LOCUS       DAZKKZ010000001        85421 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.001, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000001 DAZKKZ010000000
VERSION     DAZKKZ010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 85421)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 85421)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..85421
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.001"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            179..697
                     /locus_tag="ACG8LA_000001"
     CDS             179..697
                     /locus_tag="ACG8LA_000001"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HFQ0202345.1"
                     /translation="MPDYKKITFISSITLIIFLILILLVVLVPRIFGLTPYIIEDKEM
                     SPYYAQGNLIYVRPKNTNEILVGDIITYYENSGKKISTRRVIAVENNHEDFYTKADTK
                     TYIEPGVVKKRNIIGSPIFQIPYIGLVLSKTAFAWIQGLFFTIAFCLTGITAWNTFVE
                     LKKKRRRTQKFL"
     gene            825..1508
                     /locus_tag="ACG8LA_000002"
     CDS             825..1508
                     /locus_tag="ACG8LA_000002"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HFQ0202346.1"
                     /translation="MRNEMMHRPVVKEELLDFMRTQQKKLPGELGKLEEEAHVAEVPV
                     IPHETVVFLKFLLGQLQPERILEIGAAIGFSSSVMATTIGENAHVTTIDRFDVMIEKA
                     KKNYERLGLTDKVTLLEGQAADILPELSGPYDFIFMDSAKSKYIEFLPECLRLLRKGG
                     VLMVDDIFQGGTILLPDEEIPRGKRAIHRKLNEFLRVVMDHPDLTSTILPLGDGVILM
                     TKESETIEL"
     gene            1817..1890
                     /locus_tag="ACG8LA_000003"
     tRNA            1817..1890
                     /locus_tag="ACG8LA_000003"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1851..1853,aa:Arg,seq:tct)
     gene            2049..2408
                     /locus_tag="ACG8LA_000004"
     CDS             2049..2408
                     /locus_tag="ACG8LA_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 domain-containing protein"
                     /protein_id="HFQ0202347.1"
                     /translation="MTILSRILVTLVAIEFFYIMYIETVRTDSDTTSRVFKMSKEELS
                     RKSVQTLFKNQGVYNGLLGVGLLYGAYLSSASKEITSMLLISIFFVALYGSLTSDRWI
                     LLKQGGLALLALLSIFL"
     gene            2531..4162
                     /locus_tag="ACG8LA_000005"
     CDS             2531..4162
                     /locus_tag="ACG8LA_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015103 - inorganic anion transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SulP family inorganic anion transporter"
                     /protein_id="HFQ0202348.1"
                     /translation="MFKNYVSSLKKEFSGYDLSRFQKDLLAGITVAAVALPLALAFGV
                     SSGADAAAGLITAIIAGIVIGGLSGGFYQISGPTGAMAAILMSIAATKGMQGVLLATF
                     LAGLFLLAAGLFRLGTLTSFIPAPVITGFTSGIAIIIALGQIDNLFGVHSEGTNVIEK
                     LSSYQTIGFPINTASLIMGGLVILGMFIYPKKWAKRMPSSLLAIILATAVMLLFHLPV
                     ATVGKIPQTLISSNRLNMGDFSFSALQQVAVPAISIALLGMIESLLCGASAGRMANKP
                     LDSNQELMAQGIGNLLLPFFGGIPATAAIARTSVAIKSGAQTRLAGMIHAVVLLLSML
                     VFAPVMSQIPMPALAGVLIVTAWRMNEWETIKELFTNKYWSAVLLFILTMICTVIFDL
                     SIAIVIGVIGGCVFFVVKSAAITISLETIDWQRMGLPETEKLNNWTVVYISGPLFFMS
                     SEKLKNKLEELNHHDGVIFSMRGVPSIDLTARAVFDEFQEKAEQRGQTIIYTSLQPEV
                     EKQLSHLWEHTFTHQHQTVAHALTALHAKYTAISH"
     gene            complement(4224..4865)
                     /locus_tag="ACG8LA_000006"
     CDS             complement(4224..4865)
                     /locus_tag="ACG8LA_000006"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004844 - uracil DNA N-glycosylase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HFQ0202349.1"
                     /translation="MEYPKELIQEASLRMNGRPVEGFIAGQGPLHPKLMLVGEAPGKT
                     EIDTHVPFSGQAGKELMQALSSTGLTREEVYITSAVRSRPYRVTHRINKRTQQSETVY
                     PNRTPTRSEVFAHAPILDYELMKVQPKLIATLGNIGLQRLLGKEYTVTKNHGQLYTGP
                     VLQLTEQKDAYEWSEKNYRILPLFHPAAIFYNRSLVPVIHQDWQVLASLLQQY"
     misc_feature    5051..5127
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            5147..5455
                     /gene="rplU"
                     /locus_tag="ACG8LA_000007"
     CDS             5147..5455
                     /gene="rplU"
                     /locus_tag="ACG8LA_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HFQ0202350.1"
                     /translation="MYAIIKTGGKQVKVEVGQAIYVEKLDVEAGEKVVFDEVILVGGE
                     STKVGAPTVAGATVEGTVEKHGKQKKVVTFKYKPKKHSHRKQGHRQPYTKVVIDAINA
                     "
     gene            5482..5826
                     /locus_tag="ACG8LA_000008"
     CDS             5482..5826
                     /locus_tag="ACG8LA_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HFQ0202351.1"
                     /translation="MIKGTFKRNDAGQIVSFTLTGHADAGPYGSDIVCAGVSALAIST
                     VNGIASLAGFEPIVEMNEEEGGYLYTEVTSGMTQEQNNIAEILLENLLLGLQSIEAEN
                     SEYIQIKTINDK"
     gene            5839..6132
                     /gene="rpmA"
                     /locus_tag="ACG8LA_000009"
     CDS             5839..6132
                     /gene="rpmA"
                     /locus_tag="ACG8LA_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HFQ0202352.1"
                     /translation="MLLSMNLQLFAHKKGGGSTSNGRDSESKRLGAKRADGQTVTGGS
                     ILYRQRGTKIYPGVNVGIGGDDTLFAKVDGVVRFERKGRNKKQVSVYPVAQEA"
     gene            6566..9373
                     /locus_tag="ACG8LA_000010"
     CDS             6566..9373
                     /locus_tag="ACG8LA_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFQ0202353.1"
                     /translation="MYVKEKTAHLTKAEYDQGVTTQEIAEVLGIQRTNSSKDLNQLVR
                     EGKLIKTDGRPVRYIYQTLVTHVKPVTKHVVSYKETPVSEEKNTLQIDTKDIFAKIIG
                     ANGSMKNSVEQAKAAILYPPRGLNCLITGPTGSGKTYFAHAMYHFAKAHHVIDEETEL
                     IVFNCADYANNPELLMSHLFGYAKGAFTGADEEKMGIIDQADGGMLFLDEIHRLPPEG
                     QEMIFYFMDHGTYSRLGETTKSHEANVRIVGATTEDPGSSLLETFVRRIPINIKLPAF
                     EKRPANEKVDLVKIMIAHEANRTQRKISLTEDVAKALIGSVTYGNIGQLKSNIQLVCA
                     RGFLNHMQSPEISITIDDLTEGIRSGLIQLASNRSAMAELSKILEPKITVAPNDTIMK
                     IQSDSYELPYNLYDIIGDKAALLKSDGLDQEAINHFISTDINIHLKSFYKDHGFSFNA
                     DSKLAEFVDPKIIEVTNQIYVMVKRSLPYEFQQNFIYAMSLHISSFLKKINLGEERHT
                     NDNIREMAFDFPDEYAVAKEVRSYIETYFQVEIPESEDYYLTVLLVSLRANQASGRIG
                     VVVAAHGNSTASSMVQVVQQLLDAENVRAVDMPLDMDPKTALDRIERNVQEVDEGSGV
                     ILLVDMGSLASFNSQIQRDTGIPVRTVDMVTTSLVLETVRKVSVLGTDLDMLHESLKN
                     FRGYAEISSVESVQEAKPIHKKKAVLAICASGEGTAQRIKELIERAVNKRQETELEVL
                     ALSIVEVKEELPVIQKEYQIIATTGITDLNIQAPFIPLERFIDQNIEVILDQLLMESE
                     LEETEFISLDEESAKNTCVEFISDNFIFINGSKLIDPMWQFSTQISQTTGIGDEEYGF
                     KINLVMHTAGMIERIIRNEPLTVEENELTNTTNDPLYSQLAASVVLLEDQIKVKVPIE
                     EMYYLLRLVHNQLDKKEYTVP"
     gene            9564..10055
                     /locus_tag="ACG8LA_000011"
     CDS             9564..10055
                     /locus_tag="ACG8LA_000011"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose/fructose/sorbose PTS transporter subunit
                     IIB"
                     /protein_id="HFQ0202354.1"
                     /translation="MDIRLARIDDRLIHGQVATVWSKQTGVERIIVISDVVAQDKLRK
                     FLLKEAAPPGITANVITVQKMIQIYHSGLLSRAKVMLLFTNPQDVEAVVRCGVQLKSL
                     NIGGMSFTEGKSMITNFVSVNQQDIDSFRYLNSQEVELEIRKVPADRKILLMELLAKI
                     KKV"
     gene            10158..11147
                     /locus_tag="ACG8LA_000012"
     CDS             10158..11147
                     /locus_tag="ACG8LA_000012"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose/fructose/sorbose PTS transporter subunit
                     IIB"
                     /protein_id="HFQ0202355.1"
                     /translation="MVGIILASHGQFAEGILQSGSMIFGEQENVKAVILKPSEGPDDL
                     RAKLEEAVASFDNQDEVLFLVDLWGGTPFNQSNTLFEEHKDKWAIVSGLNLPMLIEAY
                     ASRFSMESAHEIAAHIIETAKDGVKVKPEELEPAEAPKAAVEDAQPKGALPEGTVVGD
                     GKIKYVLARVDSRLLHGQVATAWTKAVQPNRIIVVSDAVSKDDLRKRLIEQAAPPGVK
                     ANVIPISKMIEVAKDPRFGNTKALLLFENPEDVLTAVEGGVDIKELNVGSMAHSVGKV
                     VVSKVLSMGQEDVEAFEKLEQKGVKFDVRKVPNDSRDNMDDILKKAKAELAKA"
     gene            11180..11983
                     /locus_tag="ACG8LA_000013"
     CDS             11180..11983
                     /locus_tag="ACG8LA_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0034219 - carbohydrate transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HFQ0202356.1"
                     /translation="MSIISIILVVLVAFLAGMEGILDEFQFHQPLVACTLIGLVTGNL
                     EAGIVLGGTLQMIALGWANIGAAVAPDAALASVASAIILVLGGQGVKGVPSAIAIAVP
                     LAVAGLFLTMIVRTIAVPIVHLMDAAAEEGNIRKVEMWHIIAVCLQGVRIAVPAAALL
                     FIPAQTVQSFLESMPAWLTDGMAIGGGMVVAVGYALVINMMATKEVWPFFVIGFVVAA
                     ISQLTLIALGALGVALALIYLNLSKMGGSSNNGGGSNSGDPLGDILNDY"
     gene            12004..12918
                     /locus_tag="ACG8LA_000014"
     CDS             12004..12918
                     /locus_tag="ACG8LA_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HFQ0202357.1"
                     /translation="MAEEKIKLSKKDRLAVAWRSTFIQGSWNYERMQNGGWAFSMIPA
                     IKKLYKTKEERSAALKRHLEFFNTHPYIASPILGVTLALEEERANGAPVDDVAIQGVK
                     VGMMGPLAGVGDPVFWFTVRPMLGALGASLAMGGNILGPIIFFLGWNIIRWAFMWYTQ
                     EFGYKAGSKITDDLSGGLLQDVTKGASILGMFVLAALVQRWVSIKFLPVVSTVKLDKG
                     AYIEWDKLPSGGEGIKSAFEQVNNGLALSPEKVTTLQDNLDQLIPGLAALGLTLLCMW
                     LLKKKVSPIVIILGLFVVGVVGHVIGLL"
     gene            13001..13375
                     /locus_tag="ACG8LA_000015"
     CDS             13001..13375
                     /locus_tag="ACG8LA_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HFQ0202358.1"
                     /translation="MVQSINTKVDLVIDATSFTGLTDYGQIMIGNNGFEFYHARDRRK
                     YIQIPWEEVDYVLASVMLKGKWIPRYAIQTKKNGTYTFSSKEPKKVLRAIREYVDEDR
                     MVQSLSFFDVVKRGIRSMFKRK"
     gene            13514..13759
                     /locus_tag="ACG8LA_000016"
     CDS             13514..13759
                     /locus_tag="ACG8LA_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HFQ0202359.1"
                     /translation="MSWLWTLIVGAVIGAIAGAITSKGNSMGCVTNIIAGLVGSSIGQ
                     AIFGEWGPKAAGMALIPSILGAVILVAVVSFFFGKRS"
     gene            13931..14995
                     /locus_tag="ACG8LA_000017"
     CDS             13931..14995
                     /locus_tag="ACG8LA_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M24 family metallopeptidase"
                     /protein_id="HFQ0202360.1"
                     /translation="MMLRVEKLRKKMQEENLDSFLVTSPYNLRYLTNFTGTTGLAVIT
                     LEKAFFITDFRYTEQAAAQAQGFEIIKNVGPIFDEVANLVRKEELHSLAFEETTVSFL
                     EYSVLEEIIDAELVPVSQMIEELREVKDEEEIAIIEKACHIADMAYDHILKMIQPGMT
                     EIEVANQLDFYMRSLGASGVSFDTIVASGLRSAMPHGVASKKIIEQGDLITLDFGCYY
                     EGYVSDMTRTFAIGDPGEKLKEIYQIVLDAQLAVIDAAKPGMTGVQLDAVARDYISKH
                     GYGEAFGHSTGHGIGLEIHEGPNVSSRAEKQFVPGNVITDEPGIYLPGIGGVRIEDDL
                     LITEDGNRVLTRSPKELIIL"
     gene            15241..15666
                     /locus_tag="ACG8LA_000018"
     CDS             15241..15666
                     /locus_tag="ACG8LA_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HFQ0202361.1"
                     /translation="MADEKNLILNANQDLGEIVIAPEVIEVIIGIAASKVEGVYGMRG
                     TFASNVTELLGRAAHGKGVYLANEEDGLKVDLYCYLEYGVSVPKVAMEMQERVSQQVL
                     FMTDIDLSEVNIHVVAVVPEKLEQPTIEELFEDEEEENE"
     gene            15659..16108
                     /gene="nusB"
                     /locus_tag="ACG8LA_000019"
     CDS             15659..16108
                     /gene="nusB"
                     /locus_tag="ACG8LA_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HFQ0202362.1"
                     /translation="MNKELSRHEIREMALQALFPLDFNADLTKEDAIFNAIELDHRDM
                     INEDESEFVPVYLDTLVGGVCAKKDELDKVIEKHLKNNWHINRISKMDLVILRIAIFE
                     MTYVTDVPAAVALNEAIELAKTFSDDRSRKFVNGVLSNVLKELEAGA"
     gene            16205..17059
                     /locus_tag="ACG8LA_000020"
     CDS             16205..17059
                     /locus_tag="ACG8LA_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004488 - methylenetetrahydrofolate
                     dehydrogenase (NADP+) activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HFQ0202363.1"
                     /translation="MAELINGKELAEKMQAEIAEKIQKLKDNGIHPGLVVLLVGENPA
                     SQIYVRNKERVAKEIGIHSLVERYPETISEDELLAEIEKYNQDPSFHGILVQLPLPKH
                     IDEEKILLAIRPEKDVDGFHPMNLGRLLAGKPDKIPCTPYGIMKMFEAYSIDPAGKRA
                     VVIGRSNIVGKPMAQLLLMADATVTVAHSKTENLAELAQEADILVVAIGRGHFVTKEF
                     VKPGAVVIDVGMNRDANGKLIGDVKFDEVEPIAGWITPVPKGVGPMTITMLMYQTVKS
                     AEAFGAGE"
     gene            17060..18397
                     /gene="xseA"
                     /locus_tag="ACG8LA_000021"
     CDS             17060..18397
                     /gene="xseA"
                     /locus_tag="ACG8LA_000021"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA];
                     GO_function: GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA];
                     GO_process: GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HFQ0202364.1"
                     /translation="MAQEYLTVTTLTKYLKRKFDADPYLERVYLTGEISNFRLRANAH
                     QYFSLKDDHAKISAIMFKGAFQKLRFQPKEGMKVLVVGRISLYEAGGSYQIYVEHMEP
                     DGIGALYQELEERKEKLMKEGLFQGPKKMLPRFPKRIAVLTSPSGAVIRDIITTVKRR
                     YPIVQLVLFPTVVQGNQAADNVVRNIQRVEEMGNFDTMIIGRGGGSIEDLWPFNEERV
                     ARAIYQANTPVISSVGHETDTTIADLVADVRAATPTAAAELAVPVLSEELMRIQERQA
                     RLQQAFVRQIQRKQERFERARRSYVFRQPERLYEGQTIKLDQLKQRLYQATQQIYHAK
                     EKQTIALSHQLEQVAPLYRVKAARQETAYLEKRLEEKIQQYMKQQQQRFAQAVQSLDL
                     LSPLKIMGRGYSYTTLNDQVVKSVTEIHQGDLLTIHYQDGIVKGQVQEIDKGE"
     gene            18402..18626
                     /locus_tag="ACG8LA_000022"
     CDS             18402..18626
                     /locus_tag="ACG8LA_000022"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HFQ0202365.1"
                     /translation="MENPTFEESLQELEKIVMQLEQGDVPLESALDSFKRGMELSKHC
                     QDTLAKAEETLTKMMTESNEEVDFDGNEES"
     gene            18628..19518
                     /locus_tag="ACG8LA_000023"
     CDS             18628..19518
                     /locus_tag="ACG8LA_000023"
                     /EC_number="2.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004659 - prenyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HFQ0202366.1"
                     /translation="MRLTDFSAIHLPAVEKEILSFLDEHTTDRGLYDAMSYSVKAGGK
                     RIRPLLLLTAVASFDEPIDVPVYQVAAALEMVHTYSLIHDDLPAMDNDDLRRGKPTNH
                     KVFGEALAILAGDGLLTGAFQLISMAHLGNSPKLLLLQQLAVCAGSQGMVAGQAADIE
                     GESKKLSLEELAFIHERKTGHLIRYALLAGGILAKQPEEILLLLQRLAEHLGLAFQIR
                     DDLLDVIGTTKTLGKTAGKDERMEKNTYPRLLGLEKTREALEIELLSANKIIDKLEED
                     VFSFDGGLMRQMIKQFDVEK"
     gene            19527..20345
                     /locus_tag="ACG8LA_000024"
     CDS             19527..20345
                     /locus_tag="ACG8LA_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HFQ0202367.1"
                     /translation="MEKERVDVLAVKQGLFETREQAKRSVMAGLIYNEKNERFDKPGE
                     KIPVSSELRVKGKKLPYVSRGGLKLEKALKAFDLSVEGKTLLDIGASTGGFTDAALQN
                     GAKMSYALDVGYNQLAWKIRQDPRVVVMERVNFRYAKPEDFTLGIPEVAVIDVSFISL
                     KLMLPPLHAILKEEGEVIALIKPQFEAGREAVGKNGIVRDPQTHQKVLEDILSFAAQG
                     GYDVLELSYSPITGGEGNIEFLAHLRKVPESGTINSAINMAEVVSNAHEQFDHK"
     gene            20452..20901
                     /locus_tag="ACG8LA_000025"
     CDS             20452..20901
                     /locus_tag="ACG8LA_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HFQ0202368.1"
                     /translation="MRKKDRHRLITRLLSEQDIRKQEEFVEILKSKGISVTQATISRD
                     IKELKLIKVPASDGGYRYSIPAETNEDVNTKLEKLLKDAFVAVDQMEKFVILKTLPGN
                     ASAAANLIDKRYKKELFSIINDDDNVLMITRTEDQAVLLKKDFLHYL"
     gene            20919..22601
                     /gene="recN"
                     /locus_tag="ACG8LA_000026"
     CDS             20919..22601
                     /gene="recN"
                     /locus_tag="ACG8LA_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HFQ0202369.1"
                     /translation="MLQEISITNFAIIPELRLSFHEGMTALTGETGAGKSIIIDALGL
                     LAGGRGSSDYIRQGAEKCVLEGLFELPKQEGFSELMVELGIETDEDNLIVRRDMSLTG
                     KNVCRVNGHIITLANLRRIGSYLVDIQGQNEHQELLQPESHLALLDRFGDVAFQQKKK
                     SYQQEYISYRELEKRVRKVQQNEKSYVQRIDMLHFQQEEIAAADLQVGEEEKLKEERE
                     KLSNYQKIADGLAAGYGALTNNEQNSVDGVGLAVSELQGIAHLDVEYEAIYENIQSAY
                     YLLQDAIGDMSRQIDLLELDESRLEEVTQRLELIRQLKRKYGESIESILAYYDEITEE
                     LASSDFSEGQLDKMKEELEQKELLLQQQAADLHEARKKIAKELEKSILHELKSLYMEN
                     TEFEVRFLKEENRQLNHDGFDQIEFYITTNPGEPLKPLVKVASGGELSRMLLALKTIF
                     SSEQGVTSIIFDEVDTGVSGRVAQAIADKISQISKYSQVLCITHLPQVAAVADYQYYI
                     VKAVIDGRTQTSVSELKTKEREEEIARMLAGSEITKLTLEHAKELLKLAKRT"
     gene            complement(22656..22772)
                     /locus_tag="ACG8LA_000027"
     CDS             complement(22656..22772)
                     /locus_tag="ACG8LA_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HFQ0202370.1"
                     /translation="MREKKQTSTFAKVTKFVIWTMLILTIGSVVLTAVMSVM"
     gene            complement(22845..23801)
                     /locus_tag="ACG8LA_000028"
     CDS             complement(22845..23801)
                     /locus_tag="ACG8LA_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HFQ0202371.1"
                     /translation="MIKYFTLDNEKLRNTGKETDQTIWYCVERPNQEEIHQLTHQFEI
                     PSDYITSILDDAENSRTEEFNQSKLTKPALLLLQYPFAKTSPSGYFQVDTYPLSIILT
                     PKKKLITITNHEPLFLKKVFSQTFPKSDISPNLNIFFQFIWQVTLSYNSYLATLQSQC
                     DTLEAKLQVSTENKQLYQIMDIQKSLVYFREATSANLDALKELAQNKLFQENHALKNH
                     LRDVLVETEQAMTTSRIQLKLVEQMNQTFSAIVSNNLNNIMKILTSLTIILTIPTIVG
                     SIYGMNIKLPIAERDDAFIWLVLLTLFICIVTTYYLKKGKFL"
     gene            23972..24340
                     /locus_tag="ACG8LA_000029"
     CDS             23972..24340
                     /locus_tag="ACG8LA_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HFQ0202372.1"
                     /translation="MGTFTPLILFWYIYPVIVLFGCQFLVKLFSLNRRFKIKAPDLAI
                     PFLWGGMHALSRNTGTISILPFFFISVLLMGICIAVFQAYYYEEIIYPRYFKMTWRLV
                     FLLTIVLYAVLIIVNILSYL"
     gene            24510..24941
                     /gene="mraZ"
                     /locus_tag="ACG8LA_000030"
     CDS             24510..24941
                     /gene="mraZ"
                     /locus_tag="ACG8LA_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005881057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="division/cell wall cluster transcriptional
                     repressor MraZ"
                     /protein_id="HFQ0202373.1"
                     /translation="MLMGEFQHNIDAKGRLIVPSKLREELGEKFVLTRGLDGCLFGYP
                     MSEWENLEAKLNEMPLAKKDARTFVRFFYSAATECELDKQGRINIPSTLRNYAALTKG
                     CVVIGVSNRIEIWDETRWQDFSAAAEENFDEIAESMIDFGL"
     gene            24962..25921
                     /gene="rsmH"
                     /locus_tag="ACG8LA_000031"
     CDS             24962..25921
                     /gene="rsmH"
                     /locus_tag="ACG8LA_000031"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016434 - rRNA (cytosine)
                     methyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HFQ0202374.1"
                     /translation="MTETFQHYTVMLKETVDGLNIKPDGVYVDCTLGGAGHSEYLLSQ
                     LSSKGHLYAFDQDQKAIDHAKLRLASYVEQGMVTFIKANFRELEERLSEHVDKVDGIL
                     YDLGVSSPQLDEAERGFSYHQDAPLDMRMDQSAPLSAYHVINEYSYHELVKIFFRYGE
                     EKFSKQIAREIERVRKTKPIQTTGELVEIIKQVIPAPARRKGGHPAKRIFQAVRIAVN
                     DELGAEEASLEQAIRLLKVNGRISVITFHSLEDRIVKSMFKEYSTVQDLPPGLPVIPD
                     EFQPELKVITRKPILPSEEELTENNRSRSAKLRIAEKIRMKEE"
     gene            25926..26327
                     /gene="ftsL"
                     /locus_tag="ACG8LA_000032"
     CDS             25926..26327
                     /gene="ftsL"
                     /locus_tag="ACG8LA_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HFQ0202375.1"
                     /translation="MAELKKMQDYEYDLPELVDQPEQQMPDSSSNQEIILPQSPAKRL
                     KQISALEKIAVASVAIAIVALCVLTVMLRTNISGAEKEITSIQTEINDKKQEKTSLEQ
                     EKNELSRTERIKQIAEEKGLSINDDNLRKVK"
     gene            26328..28520
                     /locus_tag="ACG8LA_000033"
     CDS             26328..28520
                     /locus_tag="ACG8LA_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="HFQ0202376.1"
                     /translation="MSLKNKIRRFMEKKNLNPMNNRKKVGIILFATSIGLFFLFAVRF
                     SYIVIGGHVAGTSLAEKTKQLYQGSEVVKAKRGTIYDRNGVALAEDASSYSIKAILSK
                     TYTSGDKKLYVEEKNFDKIAEILHKNLSIDKKDALNILEDGAKKELYQVEFGSYGKNI
                     SQETKQNIEADMKKEGVAGLYFVDHQARMYPNGVFSSHFIGYAVPDKDENGLVGKLGL
                     ESAYNDILSGKDGKIIYQKDNFQNPLPGTVAEEEKAVDGQDIYTTLDSRLQSYLETLM
                     DQVNEEYQPEELTAVLMKAKTGEILAMGQRPTFNPETMEGLTGKDAIWRNFLVQDSYE
                     PGSTMKVFTTAAAIEEGEFNENETFQSGKIQVEDATINDHDFGEKGVLTMRQALSWSS
                     NVGMVILEQRLGGRWYNYLQKLGFGQSTHSGLDDEVNGALPTLNIVDRAMSAYGQAVG
                     VTNFQMMKAFTSIANNGTMIQPRYISKVVDPQTGEERTTQTEVLGQPFSKETTEKVRE
                     YMRDVVESENYGSAYGVYSVPGYNVSAKNGTAQIASDTGGYQTGDTAYLYSIVEMVPS
                     EDPDYVLYLTMKHPKTYDRMALAKIANPLMKRAMDFKETEEDSDTETKTEKVSVADYR
                     NLEADVAAADAQKSGLQPVVIGNGKKVQKQSTANGDQLISGEKLILYTGGDKLMPDVT
                     GWSKADIMKLGKILGIEVSFDGDGYCVKQELAPYEKITEDKLSFTLEE"
     gene            28546..29508
                     /gene="mraY"
                     /locus_tag="ACG8LA_000034"
     CDS             28546..29508
                     /gene="mraY"
                     /locus_tag="ACG8LA_000034"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008963 -
                     phospho-N-acetylmuramoyl-pentapeptide-transferase activity
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HFQ0202377.1"
                     /translation="MEWTQALIPIVSSCAMTIAAMPLFIGYFQMKKQGQAIREEGPKW
                     HNSKAGTPTMGGLVFLIGSILTGIWVGAWQKQLTPTLFILLFVLALYGVIGFLDDFIK
                     IFKKRNMGLNSKQKLIGQILGGIIFYLVYRSEGYPGVLNFFGLDLPLGIIYGIFALFW
                     LVGFSNAVNLTDGIDGLVAGLGSISFAAYGLIAWHQHQYDVLIICLSVLGGLLGFFVY
                     NRKPAKIFMGDVGSLALGGLLAAISIMLNQEWTLLLIGLIYVMETASVMLQVTSFKLT
                     GKRIFKMSPIHHHFEMCGWSEWKIDTVFWLISIVTSLITLWIVW"
     gene            29522..30883
                     /gene="murD"
                     /locus_tag="ACG8LA_000035"
     CDS             29522..30883
                     /gene="murD"
                     /locus_tag="ACG8LA_000035"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008764 -
                     UDP-N-acetylmuramoylalanine-D-glutamate ligase activity
                     [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HFQ0202378.1"
                     /translation="MKKISTYENKKVLVLGLAKSGVSAAKLLHELGALVTVNDGKPFD
                     ENPEAQELLSLGIKVITGSHPIELLDEEFSLMVKNPGIPYSHPLVAKAQEMGIPVITE
                     VELAYEVAECPIIGITGTNGKTTTTTMTGLLLNAGADQGIARLAGNIGYPASGVAQEA
                     KSEDKIVMELSSFQLMGITDFRPHIAVITNIYEAHIDYHGTRKEYVKAKWNLQKNMTE
                     KDYLILNWNQSELQELAQRTKARVLPFSTKEVLEDGVYADDYSIYYKKEKIMEISELG
                     VPGKHNVENALAAISVAKLYGISNEAIRETLHFFHGVPHRTQYVGEIQGRKFYNDSKA
                     TNILATKMALSGFETSKVVLLAGGLDRGNTFDELIPSLKGIKAMVVFGQTKEKLMDAG
                     KKAGIETIVTADSVEQAVPLALENSTDGDVVLLSPANASWDQYPNFETRGNRFMEAVN
                     RLK"
     gene            30909..31997
                     /gene="murG"
                     /locus_tag="ACG8LA_000036"
     CDS             30909..31997
                     /gene="murG"
                     /locus_tag="ACG8LA_000036"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050511 -
                     undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HFQ0202379.1"
                     /translation="MKILVTGGGTGGHIYPALAFVNYVKTQEPNAEFMYVGAKRGLEN
                     KIVPDTGMPFHTLEIQGFKRKISMHNIKTVRLFLKSIRQAKKILSDFQPDIVIGTGGY
                     VSGAVVYAAAKMGIPTVIHEQNSVPGVTNKFLSRYVDRIALSFKDAASFFPENKAVLV
                     GNPRAQEVADTKKSDILKTFDLDPEKKTVLIFGGSQGALKINQAVSVFLSEYIPSSYQ
                     VLYASGDRYYEEILNKINPEIQNISVQPYIKNMAEVMASSDLLVGRAGATSIAEFTAL
                     GLPAVLVPSPYVTNDHQTKNAMSLVHAGAAKMIADNELTGESLSQTVNEIMGDEELQK
                     QMCRASKEQGIPDASKRLYDLVKQIIKK"
     gene            32012..33232
                     /locus_tag="ACG8LA_000037"
     CDS             32012..33232
                     /locus_tag="ACG8LA_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsQ/DivIB"
                     /protein_id="HFQ0202380.1"
                     /translation="MSKKKEPKKLSHPSSDENNLTPWQKANRKYLAEQEMKNQEPKKE
                     DITLDTPLSDSEEEKTVQEEQQEESQSEKKIEFFEEIKQKKNGGPYNGSFLNRLPNLK
                     SQRHKVLFRRLALIITVLGIPLIFLIYYVSPYSKLQAVAVSGNKTVNSQEIISDTKLS
                     LGENVWGQYFHRSTYIDRLKKAQPRIETANIHFKGMNEFDLDVTEYKEIALIAKNNQY
                     YPVIENGTVLDEKVANPTKNLPILEEFKDSAKIKELTKQYNQLSSELQKAISEIKYTP
                     RASNKNLIQLNMNDGNQVIVNINNLANQMKYYSQVAKDMDEKGVIDMEVGIFSHPYGS
                     TQETEESGQSEETTESEENADQTNESSEEAETQKAQTPGSSSTNGSSDSNDSSETSQI
                     EDNPSTTPSSLNEN"
     gene            33388..34713
                     /gene="ftsA"
                     /locus_tag="ACG8LA_000038"
     CDS             33388..34713
                     /gene="ftsA"
                     /locus_tag="ACG8LA_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0043093 - FtsZ-dependent cytokinesis
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HFQ0202381.1"
                     /translation="MAKTGMYVGLDIGTTSVKVVVAEYIDSQMNIIGVGNAKSEGINR
                     GIIVDIDKTVQAIQRAVRQAEEKAGIQIKGVSVGLPANMLEVENCQGMIAVNGDSKEI
                     TDEDVRNVASAALVRSIPPERQIVSILPQDFTVDGFEGIKDPRGMIGVRLEMYGLLFT
                     GPKTIIHNIRKCVENAGLIVNEMVITPLALTESILSDGEKDFGTIVIDMGGGQTTTAV
                     MHDKQLKFTNLDQEGGEFVTKDISIVLNTSFNNAEALKINYGDAYPERTSPDEEFPVD
                     VIGQSEPVKVDERYLSEIISARMEQIFNKAKDALDQIEALELPGGVVLTGGAASLPGV
                     VDLAQEIFGVNVKLYVPNHMGLRNPVFTNVISIVDYSANLSEVYQLAKIAVTGETSAA
                     RQMVVEQETTNTYESYEAPEETIYDEPEPKESGENVKNKIKGFFTNIFD"
     gene            34736..35977
                     /gene="ftsZ"
                     /locus_tag="ACG8LA_000039"
     CDS             34736..35977
                     /gene="ftsZ"
                     /locus_tag="ACG8LA_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HFQ0202382.1"
                     /translation="MEFSIDNNINDGAVIKVIGVGGGGGNAVNRMIEENVKGVEFITA
                     NTDVQALKNSKAETVIQLGPKYTRGLGAGSQPEVGQKAAEESEQSLREALDGADMIFI
                     TAGMGGGTGTGAAPIVAGIAKELGALTVGVVTRPFTFEGPKRGRFAAEGIARLKENVD
                     TLLIISNNRLLEVVDKKTPMLEAFREADNVLRQGVQGISDLITAPGYVNLDFADVKTV
                     MENQGTALMGIGVASGEDRVVEATKKAISSPLLETSIDGAEQVLLNITGGLDMTLFEA
                     QDASDIVANAATGDVNIILGTSINEEMGDEIRVTVIATGIDESKKERKSSRPARQAQM
                     QSPAQKTVLDMDQAKPTSSEEENSFGDWDIRREQNVRPRVDDSNFDNIEKKEFDTFNR
                     EETKSHGDDELNTPPFFRRKK"
     gene            35994..36671
                     /locus_tag="ACG8LA_000040"
     CDS             35994..36671
                     /locus_tag="ACG8LA_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HFQ0202383.1"
                     /translation="MIADNLQKIKQEIQDSCALVHRDPKEVTLVAVTKSVESAQAEEL
                     VRAGVMNCAENRVDKLLEKKQDLFDFPEIKWHLIGNLQRRKVKLIVNEIDYFHALDSL
                     RLAEEIQKRLEKELSCFIEVNVSGEESKHGISPDELLPFVESLAACTKIKVVGLMTMA
                     PKEASDEQIHKVFGTLKELRDLVQAKGYAHAPCSELSMGMSQDFQIAIEEGATFIRVG
                     TALFKDE"
     gene            36685..37284
                     /locus_tag="ACG8LA_000041"
     CDS             36685..37284
                     /locus_tag="ACG8LA_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HFQ0202384.1"
                     /translation="MPLLNRGAIANFFGLADEEEYEYQDYPETTKKAVQPTKKNTTQN
                     QSTHSVSAANTHEKQKTATSRPVTHESIQPAEKKKVIELHQSPTKTVAKERTASRTST
                     QPKANLAGKITVMEPRAYSEAMAIAKRIIAGEATLVNFHLVEEKQARRIVDFLTGTVY
                     ALDGDIKRVGDEIFLCTPTGMEIDSSTAQSFADANLFDL"
     gene            37365..37586
                     /locus_tag="ACG8LA_000042"
     CDS             37365..37586
                     /locus_tag="ACG8LA_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HFQ0202385.1"
                     /translation="MVYALLSWFPGGYQSGLGRLLAKICEPYISLFDRLPLRIGPLDF
                     TILGAILILNLAVQGLAQIVIWITVHLVY"
     gene            37635..38417
                     /locus_tag="ACG8LA_000043"
     CDS             37635..38417
                     /locus_tag="ACG8LA_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HFQ0202386.1"
                     /translation="MDANVYQHFRADERTFIDSVGDWIEQVQGQYAPYLTEFLDPRQS
                     YILETLIRQSSDLRFMFYGGYEQAERKRCLIFPDYYEPVEEDFETALYEIHYPSKFAS
                     LSHGKILGTLVGTGIKRSYFGDIISDGDRWQVFIANEVDHFVAAQVTKIGKVAVRLEP
                     IKYTEMIMPKDSWTQERGTVSSMRLDSVISEIYNISRQRSKQLIEAGKVKVNWTENTR
                     PDFVLELLDIISVRGYGRVQIQELEGKTKKEKYRVLFGVLRK"
     gene            38438..39145
                     /locus_tag="ACG8LA_000044"
     CDS             38438..39145
                     /locus_tag="ACG8LA_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HFQ0202387.1"
                     /translation="MALTPLDIQNKTFPTKMRGYNQDEVDDFLDLVVRDYEELTQRNR
                     ELEKAVKHSEEKLEYFNELKDALNQSIIVAQDTADKVKTSASKESEVIVTSAQNKADE
                     LVANAEKRAHQLTTDAEEKARKILTDATEKARQLATETEDLKKKTRVFHQRISLMLES
                     QLEQVKSPEWDEILQPFSSYVTDSHEVIKEVLAKQLDNENDTDVNSDTGVIEAPMTAF
                     DTQAIDISIVPGENENE"
     gene            39407..42205
                     /gene="ileS"
                     /locus_tag="ACG8LA_000045"
     CDS             39407..42205
                     /gene="ileS"
                     /locus_tag="ACG8LA_000045"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004822 - isoleucine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006428 - isoleucyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HFQ0202388.1"
                     /translation="MKMKETLQLGKTKFPMRGNLPNREGEWQKEWEENRIYQKRQELN
                     EGKPSFVLHDGPPYANGNIHLGHSLNKISKDIIIRSKSMSGYRAPYVPGWDTHGLPIE
                     QVLANKGVKRKEMSMAEYLEKCREYALSQVDKQRADFKRLGVAGDWEHPYVTLDPSYE
                     AAQVRVFGKMAEKGYIYKGLKPIYWSPSSESSLAEAEIEYKDVKSPSIFVAFNVKDGK
                     DILDEDTAFVIWTTTPWTLPANQGIAVNPKFTYVLVEADGRKFVVAKDLLETVQSEIG
                     WENVTVLKEFAGQEMEYMTASHPFYERESLVILGDHVTLDAGTGLVHTAPGHGEDDYI
                     AGSKYKLSVVSPVDSKGLFTEEAPGFEGIFYDKANPMITDLLKEKGALLKLDFFTHSY
                     PHDWRTKKPVIYRATPQWFASIDKFRQNILDEVEKVEWVIPWGKTRLYNMIRDRGDWV
                     ISRQRAWGVPLPIFYAENGEAIITPETIEHVAKLFAEHGSIIWFEKEAKELLPEGFTH
                     PGSPNGEFTKEKDIMDVWFDSGSSHEAVLRQRPELSFPADMYLEGSDQYRGWFNSSIT
                     TSVAINGVAPYKSVISQGFALDGEGRKMSKSLGNIIAPEKVIKQFGADILRLWVSSVD
                     YEADVRVSMDILSQVAEVYRKIRNTMRFLLANTEDFDPKKDTVSYNDLRSVDKYMTVR
                     LNQVIKEIREEGYDKYNFMHIYRTVMNFLTVDLSSFYLDFAKDVVYIEAEDDYQRRCM
                     QTVFYQTAVALTKLLTPIIPHTAEEIWSFLKEEEEYVQLSEFPGYEEFANQEELMDTW
                     TAFMDFRDNVLKALEEARNSKLIGKSLEAKLTVYPKQQVREMLKALDADIAQLLIVSP
                     DYFEVMAADEQVPDNAMVFDDVAITVEKADGETCDRCRQVRKDVGVDEKLPHLCGRCA
                     KIVEDFYPEAVAEGFEEK"
     gene            complement(42254..43780)
                     /gene="zwf"
                     /locus_tag="ACG8LA_000046"
     CDS             complement(42254..43780)
                     /gene="zwf"
                     /locus_tag="ACG8LA_000046"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004345 - glucose-6-phosphate
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016614 - oxidoreductase activity, acting
                     on CH-OH group of donors [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HFQ0202389.1"
                     /translation="MSNEKNVLFTIFGGTGDLAQRKLYPSLFRLYRKGNLGEHFAVIG
                     TARRPWSDEHYREVVKETIRALNPSDEEATTFASHFYYQSHDVNDSTHYQTLKELSDR
                     LDGHYQLNGNRVYYLAMAPQFFGTIVSHLKSQNIMTKNGFNRLIIEKPFGSDYQSAFE
                     LNQQIREVFPEQDIFRIDHYLGKEMIQNISAIRFANNIFEAQWNNRYIDNIQITFGEN
                     LGVEDRGGYYDHSGALKDMVQNHILQVVALLAMEPPVAFSEKEIRTEKIKALKAIRIY
                     NEEEVLENFVRGQYAQGELDGVQFKGYREEDKVDAQSETETFVAGKFTIDNFRWSGVP
                     FYVRTGKRLTEKGTRINIVFKQVPVNVFKTSVDEPCDDTTLPPNVLTIYIQPTEGFSL
                     SLNGKEVGQGFETEPIKLEFRNSAEMVENSPEAYEKLLLDALNGDGTNFSHWEEVAQS
                     WHIVDVIRKAWDQTQPDFPNYKAGSMGPKAAFELLEKDGFEWIWQPDNWYRERGKLND
                     "
     gene            complement(43795..44442)
                     /locus_tag="ACG8LA_000047"
     CDS             complement(43795..44442)
                     /locus_tag="ACG8LA_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HFQ0202390.1"
                     /translation="MTPNREDYLKIILELGGDTTKVNNKQIVSSLDVSAASVSEMISK
                     LVKEELVEHSPYQGVQLTASGLQKASSLIRKHRLWEVFLVEHLDYSWNEVHDDAEVLE
                     HVTSEHLADHLENYLNHPEHCPHGGSIPKKEEVVHEERRQTLESYPVGTKVRIARVLD
                     EKELLDYLVTIDLNINEEYEIVDIAAYEGPITIQNDRKKIPVSFKAASTIFVDKI"
     gene            complement(44626..44955)
                     /locus_tag="ACG8LA_000048"
     CDS             complement(44626..44955)
                     /locus_tag="ACG8LA_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4828 domain-containing protein"
                     /protein_id="HFQ0202391.1"
                     /translation="MIYFLGSLITVLSSFIYLKKKKQAEKSEGLSKYQGTWFFSDSQQ
                     KQQLQITSDYTFLINGQSLGTSVVEIDEYRLVVRDQYGFYLIFSYPEQTLYDESADTS
                     YKLLSEK"
     gene            45132..45860
                     /gene="sfsA"
                     /locus_tag="ACG8LA_000049"
     CDS             45132..45860
                     /gene="sfsA"
                     /locus_tag="ACG8LA_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA nuclease SfsA"
                     /protein_id="HFQ0202392.1"
                     /translation="MKYQQVEIAFFIDRPNRFIAHCMKKDGEIIIAHVKNTGRGKEVL
                     IPGAEVAIVFAPGPKRKTAYDLIAVKKKGDWFNIDSQLPNRLAIDGILDGTILLPGLT
                     GPFTVYKREVTYLHSKFDIYLETVVGQKAFVEVKGMTLENKAIGAFPDAPTLRGLKHI
                     GELTYAAQDGYAAYVLFIAQFEHLHLATIHEEMQPALADMVRHAQQSGVQILAYNCQV
                     SADEVTVKQAIPFDVDIPFEDPIQ"
     gene            45876..46889
                     /locus_tag="ACG8LA_000050"
     CDS             45876..46889
                     /locus_tag="ACG8LA_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFQ0202393.1"
                     /translation="MINLGIIGTNWITHQFVQAALSTKKYELTAVYSRHLEKAQEFGS
                     HYEGDIEFATDLKTFFNITHMDTIYIASPNSLHFSQAKQAILAGKNVIVEKPAFSTPK
                     EMDEIIHLANEHNVYFFEAARNIHESGFKKIADYLPLKDEIIGANFSYMKYSSRYDQV
                     LDGEEPNIFSTHFSGGALMDLGVYLVYAAVAWFGMPKEVHYFPRKISTGVDGLGWGIL
                     RYENFDVSIQPGKIGDSYLPSEIYFDSGTLVMNGVNAIEQAQFHDRAHKEIIDLAVTA
                     AENPMADEAEDFANVMAHPKDPAWGLLYEEWIELARNVNQVIYDLRKNGGIKFDADNE
                     EDF"
     gene            46889..48166
                     /locus_tag="ACG8LA_000051"
     CDS             46889..48166
                     /locus_tag="ACG8LA_000051"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HFQ0202394.1"
                     /translation="MNEFVQVFPENWQKKYEDKGFISPSLIQRAVFQPLSNKQSIVAV
                     SPTGSGKTLAYLWPLLLNVEPGEASALVIFASSQELAIQVADVAREWGKDKELKVQSL
                     VGGANVKRQIEGLKEKPEILIGTPGRILELMKAKKIKAHQVKTMVFDEADQLFDAGNS
                     QIIDQILHQAPTEYQLAFFSATADRSLESIEKITGKTFETIDVTAEDDSRKGLRHYFL
                     RVPIRKKDDYLRRLTHIEDFHGLIFFNQLTELGVMEEKLLYRGVPVGSLASDQNKLLR
                     KAALEQFKKKMVRALLTTDVAARGLDITGLPYVVNAEVPLSEEAYLHRSGRTGRMGNE
                     GIVITLVQDNNLRDLKRLLRPSNITLEEIFLYGGKLQTEQPTKEDAAPAVNKKYAKTF
                     SGKEQNPEYNKEKIRKKVKNKSKKERNKGARRK"
     gene            48229..50931
                     /locus_tag="ACG8LA_000052"
     CDS             48229..50931
                     /locus_tag="ACG8LA_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFQ0202395.1"
                     /translation="MKERQEEILQLLTENQQGLTASDVAERLTIDRSNASRYLSELYK
                     AHHIVKTAGRPVVYSLPTEKSKSDEVHVDSSTQVTFETLVGENDSLKVSIQQAKAAIL
                     YPPRGLHTIIFGETGTGKSMFAECMYHFAIDSEMLSADAPFVSFNCADYAQNPQLLFG
                     HIFGIKKGAYTGAAQDSPGLIAKADGGILFLDEIHRLPPEGQEMLFTFIDKGIYRPLG
                     ESAQVHEASVQIIGATTESSESFLSTFNRRIPMAITLPNLASRSLDERYEIISLFIKQ
                     EANRLNQRIDIEKEAILAFMLYDAEGNIGQVKRDLKLVCAKSFLHYRTHHEKKLIIRK
                     EELSLQVQKGLLKIKEIPERLDRFMDSKSQYLTFEPGFADVVWSQDPERNMQVYNDIE
                     EKVTSLSETGVENIDLETLISKDVDAYFQTYVKELTKSSIPKDLLPDEIWRLTNQLYD
                     VAEKRLDRIYNEKARFAFALHLQSTLDRVREGHMIVHPDLNNVRKNFKREFQVAIDLS
                     TIIEEEEQVEIPFDEIGFISMFLSINLGESEPVKENKVDVLILMHGRQTASSMLEMAQ
                     ELLGTKVGKAFNMPLVMEVQTMYEEVLQYVKNYQEHLTNGLLLLTDMGSLNTFSDLIY
                     EETGIRTKAITMTSTMIVIEAIRMASVGRSLEDIYQNIQLSFESIVRDQFKAEKSETL
                     QRKKAVIVTCFTGEGVAAKLYQRIMPVINQNKVELIQMQFLERESFKKHIDALLEEYE
                     IKAIAGTVDVDYQNIPFFSAYDVFDDEKLNILKRIADDEIPTAKIVDSLAGSLSDVFS
                     IDELIRSLQKTVQQIQTDLSIIVEPGVDTGIVIHLAFMLDGLIKQESHRQFEKLSIFS
                     KIYRLEMDIVRANLMALERKYQVKIPEDDIAFLTQMFLENKIKK"
     gene            51083..51400
                     /locus_tag="ACG8LA_000053"
     CDS             51083..51400
                     /locus_tag="ACG8LA_000053"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFQ0202396.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEEKGMEADIFAVSASDA
                     DNNLESKNVDVLLLGPQVRFMKAQFEQKLAPKGIPLDVINMQDYGMMNGEKVLAQAEN
                     LMK"
     gene            51430..51750
                     /locus_tag="ACG8LA_000054"
     CDS             51430..51750
                     /locus_tag="ACG8LA_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HFQ0202397.1"
                     /translation="MEDQQNLEAIMGLIMFGGNAKSDAMEAIAAAKIGDFELADRKIA
                     DAEESLIQAHHAQTDMLTQEAQGNHMQVTLLTVHSQDHLMTSIAFTDLAKEIIELYRR
                     VYSE"
     gene            51858..53318
                     /locus_tag="ACG8LA_000055"
     CDS             51858..53318
                     /locus_tag="ACG8LA_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HFQ0202398.1"
                     /translation="MNGLSSWMEKYILPVAAKIGAQKHLVALRDAFIGILPATMAGSV
                     AVMINAIIRDLPQQFNSTYADSLAADKGIFAVLNVIIGINGFVWNGTLAIAGLIFAFS
                     WGYNLARAYGVNDLAGGIVGLATLIQGISFGPALSAALDVNVPSNVADAINSSEIGAT
                     IADGTLSVGLWGWLKLDHLNGNAYFTVMIMGAISVIIFCKLMLANITIKMPDSVPPAV
                     SKAFAAILPATIALYVIAIINYIVGRVADGQLIIDLVQKYIAEPFLGLSQGLGAVLIV
                     TVFVQVFWFFGIHGSNVLAPVLEGIWGQAQLINIDIFQKGYNGKTGTPAVLDAIEDGK
                     AYMWVRGSFDAFAWFGGSGGTIVLLIAILIFSKRADYLTVAKLSIGPGIFNINEPVMF
                     GLPIVLNAIMFIPFLIAPVVATAIGWTATYLGLVAPVSQQVTWVVPPFLLSFLATGAD
                     WRAPIVTLVCMVVTFLIWAPFVISANKMDPAAGEQQ"
     gene            53386..53607
                     /locus_tag="ACG8LA_000056"
     CDS             53386..53607
                     /locus_tag="ACG8LA_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202399.1"
                     /translation="MITIASAMQQDEIKELLEGYNEEGMTFTFKEKQGIKLFFETSAE
                     DPEVAAKKAKELIKAQPWGTVLYFQSTAV"
     gene            53638..53820
                     /locus_tag="ACG8LA_000057"
     CDS             53638..53820
                     /locus_tag="ACG8LA_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3188 domain-containing protein"
                     /protein_id="HFQ0202400.1"
                     /translation="MIKNGLFLCSIGSLIVLYSLNPHSQRYDLYSMVTGLFLTGLGIY
                     FFMKGKKREEAKEKNN"
     gene            53820..54233
                     /locus_tag="ACG8LA_000058"
     CDS             53820..54233
                     /locus_tag="ACG8LA_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HFQ0202401.1"
                     /translation="MEITKKLNIPASFFYDKVMDSVLFDVRKATGKSVTRKQLKNLEY
                     VKQFSQNNRARIKIEEVIENQSYKFRTSTTKNEFVVHYQIKPLDDSTCEVHYTEKMES
                     YGMLQKLNDMLLGTILMYFKRRRFKKMLDMIEATY"
     gene            54356..55537
                     /locus_tag="ACG8LA_000059"
     CDS             54356..55537
                     /locus_tag="ACG8LA_000059"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFQ0202402.1"
                     /translation="MTNKVRELGVSSIEEMFDLATYAFNGADTPERRERFRTLAENSW
                     NYGFFDEEDRLTSQVMATPFPVNFYGQEYLMAGIGYVASYPEARGQGGINQIMEKILE
                     DCRDRKVSLSYLAPFSYPFYRRYGYEQSFDKISYQLNSRDVPFIKKKSGKIKRMDFED
                     AKAAIRRIYEQMPENQRAGLKREDWWYTYKFKQKGNYQFALHFDDNEEATGYIVYQLA
                     TSSFIIAEWGFLDHDAFCSLVRFVSSHNGAFETFEYSCGYGGNDQNYLLENPFASVMI
                     TPYMMARIVDISLFLENYPFKKRQAAFALQIEEDHYAKWNEGIVEVTIENGKNHLSKV
                     EQTKLPIVRGSIQHITQLLLGYRKVEELVFQERIQVTKEYEETLSSILPQQQPILNDY
                     F"
     gene            complement(55608..55772)
                     /locus_tag="ACG8LA_000060"
     CDS             complement(55608..55772)
                     /locus_tag="ACG8LA_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202403.1"
                     /translation="MNDKPKEKVYAERLDSSKKNREKITKEAIQDHKKENPKTKENKK
                     FKFTKKEDLL"
     gene            55926..55999
                     /locus_tag="ACG8LA_000061"
     tRNA            55926..55999
                     /locus_tag="ACG8LA_000061"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:55960..55962,aa:Arg,seq:cct)
     gene            complement(56068..57207)
                     /locus_tag="ACG8LA_000062"
     CDS             complement(56068..57207)
                     /locus_tag="ACG8LA_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFQ0202404.1"
                     /translation="MARLVKRGNSWQYEISYKKDDGKYTKIRKSGFKTKGEAKDAANE
                     LEYNLNKGLKGDRKNLLLSDYFEDWMQLYKEGTVSPITYRKYEDTLMNIKKYMPAVLI
                     SDLDRVGYQRFLNKYAKDHVKSTVIKFNNHIRASLKDAVEEGLIPFDPTRKAVIKGKD
                     SLKPKEDKYLDYDQFKSLMKLVEENLSAQYSSPMLVLVAGATGMRFAELLGLTWEDID
                     FEDQIITINKTWNYKLNEWGKTKNETSNRKISIDKHTIDLLKKFKINQKELFENFEIK
                     NPHNFVFFNLKNGLVSSNAVSKYLRKKLKELGIEKQFTLHGLRHTHASILLYQGVNIL
                     SVSKRLGHSSLETTMSTYLHIVRELEDQDKEKINTVFDSLYKNDN"
     gene            57379..57513
                     /locus_tag="ACG8LA_000063"
     CDS             57379..57513
                     /locus_tag="ACG8LA_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202405.1"
                     /translation="MIKVIFKRITELPEFRLFVDYWYVWFFIVALLIGLDVILERKLK
                     "
     gene            complement(57506..58141)
                     /locus_tag="ACG8LA_000064"
     CDS             complement(57506..58141)
                     /locus_tag="ACG8LA_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202406.1"
                     /translation="MDNSNEKLTKKEYLELIVEGGIGAIPYIGGVVQSLYFGSKNEKR
                     FKRIEKFYKNLNESLENIRDQIPEDVFNLENKDQLIGIFEGINDEVEKSKAQNKIDMY
                     KNLYKNCLLRINNASWDNEEYYLLVLNQLTSIEIQLLACLMSRGNENFTGNISMSGYS
                     QELIDGSLNRLSDFGLLEKTISSIVLGDVGKQNMGYKISHLGIQFINSTLT"
     gene            complement(58254..58889)
                     /locus_tag="ACG8LA_000065"
     CDS             complement(58254..58889)
                     /locus_tag="ACG8LA_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3221 domain-containing protein"
                     /protein_id="HFQ0202407.1"
                     /translation="MDGIFGFTGIVLFIIGLIMLIVRFIKKTNKKTPMILLIIGIIFT
                     TVGFSLSSSNEANDNNKQESSSSDTQTTTSNSSNKSLTQFEEFLETNNHDWGAFLDSY
                     YSITPATEQNTAFTKYISGKTYTFEGTVIESMTTRIAIIADKEYDDKSWNDISATPKV
                     SYVIFAKDLNNADTFTKGDKVTFTGEISSRGSNIEKSYAQWDMINSKVSKK"
     gene            complement(58923..59384)
                     /locus_tag="ACG8LA_000066"
     CDS             complement(58923..59384)
                     /locus_tag="ACG8LA_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4429 domain-containing protein"
                     /protein_id="HFQ0202408.1"
                     /translation="MEKEILIKSPGKTLIKVTDDSISIIRKGFINLVNQGIKGEKTIP
                     FKNISAVQLKKPGMSNGYIQFTLLGGNESRGGILAATKDENTVMFTKKYWNEMENLKK
                     YIEKQQSILDNNSKETQISSADEIKKYKELLDEGIINQEEFDFKKKELLGL"
     gene            complement(59514..59945)
                     /locus_tag="ACG8LA_000067"
     CDS             complement(59514..59945)
                     /locus_tag="ACG8LA_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HFQ0202409.1"
                     /translation="MYLKLKEMLSEYNLKVVYMEMKEPGFYYPKPRIIFLNENLYGET
                     AEAFHLSHELAHFSASHFEFSVLYDTSTTFHSKFETEADKIAILILLNIYIENELTDE
                     SQFNLEKFMEYYSIQNKLRYTCYAVCQCYFKKKYSYARQYV"
     gene            complement(59963..60283)
                     /locus_tag="ACG8LA_000068"
     CDS             complement(59963..60283)
                     /locus_tag="ACG8LA_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFQ0202410.1"
                     /translation="MNTYEIIKDLAKRKKISIRQLEINFGYSNGYLAKWKNNTPNSDE
                     LSRIADYFDVSVDYLLGREERETPKHVDLSEDDTVFSFDGKEISKETMRKAIAIAKAL
                     EENE"
     gene            60582..61358
                     /locus_tag="ACG8LA_000069"
     CDS             60582..61358
                     /locus_tag="ACG8LA_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor KilAC domain-containing
                     protein"
                     /protein_id="HFQ0202411.1"
                     /translation="MNTPQIFNFEQNEVRTILVNDEPYFVGKDVASVLGYSNTKDALS
                     RHVDLEDKMGSRITTSGQSREMTIINESGLYSLILKSKLPSAKKFKRWVTSEVLPAIR
                     KHGGYLTPEKVEEALLNPDTIIQLATQLKEERTGRLIAEQKIAEYEPKISYLDSILSS
                     TDSVTISQIAADYGMSPQQMNKLLHKLGIQKKVGNQWLLCKKHMNQGYTKSHTTEIPK
                     ADGGTKIVMNTKWTQKGRLFIYELLKKEGYYPQMDLEEIG"
     gene            61373..61576
                     /locus_tag="ACG8LA_000070"
     CDS             61373..61576
                     /locus_tag="ACG8LA_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0202412.1"
                     /translation="MTDIAEITQRDREKIKEYVESSKFLTYTMLAERFGISKSYLSLI
                     LNGKKTSAEANRIIDSIITMYEL"
     gene            61592..61930
                     /locus_tag="ACG8LA_000071"
     CDS             61592..61930
                     /locus_tag="ACG8LA_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF771 domain-containing protein"
                     /protein_id="HFQ0202413.1"
                     /translation="MQYLEAKIPIPEGYVIISQVDYEELKKADDTGRWMTLPEVLERI
                     NRKYDWFTSRVLKNPRYRNIIDIEKNKNGFVYYPVEGRDTYLFLRSKTLEFLETNFSE
                     ILRRQADGKI"
     gene            61917..62096
                     /locus_tag="ACG8LA_000072"
     CDS             61917..62096
                     /locus_tag="ACG8LA_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202414.1"
                     /translation="MGKFNRALVFSAPLIIYALGLWGSRQALIGTIVYMVWIFMGLDE
                     AEAEYRAKKPTEGAD"
     gene            complement(62139..62609)
                     /locus_tag="ACG8LA_000073"
     CDS             complement(62139..62609)
                     /locus_tag="ACG8LA_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202415.1"
                     /translation="MSIISFILSTFLTGIKIKGMRPQLEVELNASYFAADMIYTKVII
                     SNYSTEPAMLVNLELSSANLNRRWSATPFKKLIAKGGSVDDNRIYSEAVPLNIPPKSA
                     ISCYLAFEVGKINFNKLLNHQTKMIFTLNRTQIHKIVDIKNTNFPIEKLVKELN"
     gene            62696..63394
                     /locus_tag="ACG8LA_000074"
     CDS             62696..63394
                     /locus_tag="ACG8LA_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage regulatory protein"
                     /protein_id="HFQ0202416.1"
                     /translation="MQELVILKNKEAVTTSLQVAESFEKKHQHVLRDIDALKKDVSNF
                     GQMFVEGNEPDSYGRNRRVFFISRDGFFLLAMGFTGKKAIYFKQKYIEAFNEMEDVIR
                     KNTVPQTIEDMMIYQLEEMKDVKKDVSMLKDTMRISGQQEFEIKQKGNMKVMGVLGGK
                     ESRAYEEISKKVFSKFWSEFKRTFSIPRYGELPRKRFDDAVSFIEMWLPETAIRMEID
                     QLNRQQRLFGDDNE"
     gene            63572..63913
                     /locus_tag="ACG8LA_000075"
     CDS             63572..63913
                     /locus_tag="ACG8LA_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202417.1"
                     /translation="MEKELSTLDQYLIDPDWGKPKIEETSGRKIRRNLLTNEELAWDQ
                     DDLGNHVTIWDHVYLIHLSKHSNKPEYIYVIEDGLIDALEEYDRDNLIDISYYGPGKK
                     YIAEMEAEFDE"
     gene            63906..64577
                     /locus_tag="ACG8LA_000076"
     CDS             63906..64577
                     /locus_tag="ACG8LA_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1071 domain-containing protein"
                     /protein_id="HFQ0202418.1"
                     /translation="MSEIKGTTNFEKLFSRKLNKILKKKGNFDYLSWAHAWEIMKKND
                     PQATVTINEYKHYRVVSGTHQDFLVEEYKPFLMDETGTYVSVSVTVKGHTETELFPVL
                     DYRNQPVVKPNAMQINNSLKRCFVKALALHGLGLYVFQGEDIPTPPRIDTKKLNMLET
                     ILEAFNEQMGKDMTKTLIEYVNEQTDKLGLLADNVETIEQLSYEQCALMERAIAAKRK
                     ELDKK"
     gene            64583..65275
                     /locus_tag="ACG8LA_000077"
     CDS             64583..65275
                     /locus_tag="ACG8LA_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative HNHc nuclease"
                     /protein_id="HFQ0202419.1"
                     /translation="MFKPLIDSYSAVLKKFKGKDISATINEEVNIDRLKTMYDGYDGD
                     RVIEIRFIDPRRFTVQQRNFIYALIGDIFIDTGMPTDFWKEFFYFRFEGVTGRKISLK
                     DESNTTVSDANVLANIILDFIFEHHIPFKEGYEILPANQEYYFYKCITKRVCCICGKT
                     GADIDHFDKALGRRKRKEVDHAEYTFAALCRIHHTEKHKIGVINFKNKYQIKGIKLNQ
                     KTIKKLNIGGEK"
     gene            65272..66021
                     /locus_tag="ACG8LA_000078"
     CDS             65272..66021
                     /locus_tag="ACG8LA_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0202420.1"
                     /translation="MTEHRSYYAIIPANVRYDKRLKPNTKLLYGEITALCNERGFCWA
                     GNEYFADLYGVNKETISRWVSDLIKFGYLNREIIYKEGTNQIINRYLRINQYPIDEKR
                     NTPIDEKVKDNNTSINNTFNNTKEYIRELPPSKKSKAKPVRHKYGEYKNVLLSDEQME
                     KLKTEFPNDYQERIERLSEYCESSGKTYKNYLATIRSWARKEKSEPKNASSGYKRTGR
                     REKLPEWAIDQEAYLKKKALERANRQSKAPF"
     gene            66033..66302
                     /locus_tag="ACG8LA_000079"
     CDS             66033..66302
                     /locus_tag="ACG8LA_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202421.1"
                     /translation="MKIDYLELINEIANYKKGEELDVLRDVYDQLEEAGIEGIKNDRS
                     SWSKLRYYFALYIDGTQLRNLAYTKLLFIDCVKGLQKHLNELEQV"
     gene            66308..66472
                     /locus_tag="ACG8LA_000080"
     CDS             66308..66472
                     /locus_tag="ACG8LA_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202422.1"
                     /translation="MDLKTFTAQIELMHQEALRQSVSYEDKWLNTFHGGRESALDQVL
                     KLLKGECRDG"
     gene            66465..66764
                     /locus_tag="ACG8LA_000081"
     CDS             66465..66764
                     /locus_tag="ACG8LA_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202423.1"
                     /translation="MDKKAAMQRIIELTYSEDWQEDKKIVAEVQKLGKSMWTEKPKRR
                     TPRKIAIWHGDRILVTGTAKQLSEITGLSKNIIWDRARSLWIDSKGRQFRYVEEK"
     gene            66764..67066
                     /locus_tag="ACG8LA_000082"
     CDS             66764..67066
                     /locus_tag="ACG8LA_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like family protein"
                     /protein_id="HFQ0202424.1"
                     /translation="MDELIAKVEQWAKDKGLDQADFSKQMLKTVEEIGEVAASLARKD
                     EHGLRDGIGDVVVTLIILAMQNDMDLYECLDFAYDEIKGRTGKMVNGVFVKSSDLK"
     gene            67106..67471
                     /locus_tag="ACG8LA_000083"
     CDS             67106..67471
                     /locus_tag="ACG8LA_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202425.1"
                     /translation="MIDAKQVQKQKDGMLMFEAYVLPFLNQFEVLECSASGEELEYVV
                     IRETKENVQKLNEFLCTINCWDMIAPGFLCPAMGEFLEYCRLEDAGTLDLAYLVYNYL
                     NINTDHLWFGTAERKWVVR"
     gene            67961..68101
                     /locus_tag="ACG8LA_000084"
     CDS             67961..68101
                     /locus_tag="ACG8LA_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202426.1"
                     /translation="MNEIAADHELSETALIDQIELARQYFVPYADTWSKHKNDIIFPE
                     EQ"
     gene            68098..68280
                     /locus_tag="ACG8LA_000085"
     CDS             68098..68280
                     /locus_tag="ACG8LA_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202427.1"
                     /translation="MRATDPVIILEEAKFIWTHEEIEQARLLFSQGVKPSKVAEIMGQ
                     KILDVGLLLLHLAEKI"
     gene            68293..68487
                     /locus_tag="ACG8LA_000086"
     CDS             68293..68487
                     /locus_tag="ACG8LA_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202428.1"
                     /translation="MMIQLAGIQTGKIYFSGESKSEANQWLLKTYTNNKKLRKKYPDL
                     LLKDDQIMPEPMILTRKEGS"
     gene            complement(68520..68732)
                     /locus_tag="ACG8LA_000087"
     CDS             complement(68520..68732)
                     /locus_tag="ACG8LA_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202429.1"
                     /translation="MNINNLVKLVEQRFKESGLEQLKKDNSPELFSNFTEDDIPTLKQ
                     LKYYSDYWTQTRENELNLEKLIIKKK"
     gene            68860..69060
                     /locus_tag="ACG8LA_000088"
     CDS             68860..69060
                     /locus_tag="ACG8LA_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202430.1"
                     /translation="MKVREQFKIVSDEGNVYKIKIVNINEYREADHKYLVDLYMNDKY
                     LGEGFCGDSLFDDERILKEETE"
     gene            69057..69329
                     /locus_tag="ACG8LA_000089"
     CDS             69057..69329
                     /locus_tag="ACG8LA_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH/PUA domain-containing protein"
                     /protein_id="HFQ0202431.1"
                     /translation="MIHELKILPEYFEAVTSGRKQFEIRKNDRDFKVGDQLILREYKK
                     YIKHELPGLTRPTFSYTGDSYKAEITYITDYMQKSGYVVLGIKGVN"
     gene            69330..69515
                     /locus_tag="ACG8LA_000090"
     CDS             69330..69515
                     /locus_tag="ACG8LA_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202432.1"
                     /translation="MKVYILAITEGTWMFPVGSGKIYKSKTAAYKAFEKYKKENGGGT
                     NAKILVADNWHEEGERN"
     gene            69493..69849
                     /locus_tag="ACG8LA_000091"
     CDS             69493..69849
                     /locus_tag="ACG8LA_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202433.1"
                     /translation="MKKVNVIDLPVHFRGTNYFYASNLIQKKMSKDERKILANFYLVL
                     KIEQNVFSERRIVWEKQNQRLRRKNDVWNKRQSRMERLRKNKKATPFEIAAQYYSTIR
                     GGVCEISLVKRLPRTR"
     gene            69809..70285
                     /locus_tag="ACG8LA_000092"
     CDS             69809..70285
                     /locus_tag="ACG8LA_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma factor-like helix-turn-helix DNA-binding
                     protein"
                     /protein_id="HFQ0202434.1"
                     /translation="MRFHWLKDYQELDEQILYLKWNLNKSKLELNRWVCGDLANVRIE
                     KNSRTSSLEENIQKIENELELLIEQKEEMLLLIDSFSGIDNQIVKMKYVDQMSLEDIA
                     ESVGYSSSYVRQRHAEIRKTLNFLDEYEHRQADRLKKENEIDFYNSEKYKEQLSLF"
     gene            complement(70431..71159)
                     /locus_tag="ACG8LA_000093"
     CDS             complement(70431..71159)
                     /locus_tag="ACG8LA_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4145 domain-containing protein"
                     /protein_id="HFQ0202435.1"
                     /translation="MRGVLMLQEVNIKYRDRQNTETIYLPNSCPHCGNIMTPYVYFGV
                     SSYSAFDNDRIFGVLVQCINDECNKFYSLQFINTFNEDEGYSENILIKDYYRPPIKID
                     LPENIEKVSPTFVDIYTQATQAKSEQLEQIAGVGYRKALEFLIKDYAISKNSEDEDKI
                     KKMLLGKTIENYLNDFPKLQRLAKAATWIGNDETHYVRRHTNKDVHDMDAFIKSAAQF
                     IAADYDADLADQFINGNNFMPTTN"
     gene            71207..71485
                     /locus_tag="ACG8LA_000094"
     CDS             71207..71485
                     /locus_tag="ACG8LA_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202436.1"
                     /translation="MNDFHEAVLSIEVESSLAKVYKKAIEAENSPYRENWNGNHAHVQ
                     VENDDYRTGMNTLVISLLSHTLPNLQETIEWYERMGAKVIRTNYKGEN"
     gene            71487..71873
                     /locus_tag="ACG8LA_000095"
     CDS             71487..71873
                     /locus_tag="ACG8LA_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rho termination factor N-terminal
                     domain-containing protein"
                     /protein_id="HFQ0202437.1"
                     /translation="MAMIKIRTSISGTEYWDSEKKRTVVVPKDQEPNFEVKEEKGILS
                     DGKSFVAVNGELIAHSSEILDSDGNTAANFDGDEATNDQSTEDTDELDNMTAKELRAY
                     AKKHGIDIPGAIRAKGDIINLIREVE"
     gene            71870..72250
                     /locus_tag="ACG8LA_000096"
     CDS             71870..72250
                     /locus_tag="ACG8LA_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease signature motif containing
                     protein"
                     /protein_id="HFQ0202438.1"
                     /translation="MKYCQFDGCTNKIAKGIYCTEHKRSSRSRKKKQQAKSVYHHENK
                     PFYRTQAWKDMRQFIYEREGGHCQRCGQFIFGKRAHVHHIVPIKDNELLKLDPNNLML
                     LCSKCHPIVENETEDKKVFPSYFN"
     gene            72362..72814
                     /locus_tag="ACG8LA_000097"
     CDS             72362..72814
                     /locus_tag="ACG8LA_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P27 family phage terminase small subunit"
                     /protein_id="HFQ0202439.1"
                     /translation="MTTKAQRKAIIDEKVSAEKARILEIMNLSDLYTITLDPLIESYL
                     DIFEIYQHKYLLWKEKGFPETQKFTNKSGATNQSKHPLAQQVETWADKKMKALDLLGL
                     TNKAKTGRLIAGGSTARKDEEITRPEVKPVDELAAHRNKWRKKAGAEK"
     gene            72811..74538
                     /locus_tag="ACG8LA_000098"
     CDS             72811..74538
                     /locus_tag="ACG8LA_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HFQ0202440.1"
                     /translation="MIEPGVNYADLFAKEVRKKPKKYPKTVRLAIDRWYQWKKRKDIW
                     FDVDRANEMMDWVESFIVHTKGEMVGKPFLLEPWEKFIYSWIYGWVKENEKGQIVRVT
                     REAYVQIPKKNGKTLIAVGSLGYAMYGEGALSVDCYACASDFAQAQYAAKPFAVTILN
                     NPILLEGTKIFRGPKGTVSSITYDYIHEDMAYSNKFIVQTKNIDNIEGSNPYFVLNDE
                     LHKQEKMEQYDNFKSAQISLPQPLMFNISTAGKGSSSVGMRVYREAKEVLKRDDNDSN
                     FVLIYEPNKNYDWTDRKVWEMCNPNWGISVDLSVLESAFKTAQRSAHSKAEFLTKHLD
                     VFVNGADNFFEQDQVEPCLVTTQELGDLSGEPCYIGLDLSRTRDLTCVSLNFPTWDED
                     GKAVLKVKQLYFIPNEDLEFREKEDNVPYSDLAEQGFVEFCDGKMIDQDQILQYIEDC
                     MNLYDIQQVNYDPAMSDKLVEKLENLGLECVEVAQYPKVLNAPFDDVERLFYEKRIQF
                     DNPLFLYCTLNVVAITNINGQKAPSKRQSKKKIDGFVAFLCGHKETMNQMTDIDSDEL
                     DDYLSSIYR"
     gene            74602..75789
                     /locus_tag="ACG8LA_000099"
     CDS             74602..75789
                     /locus_tag="ACG8LA_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HFQ0202441.1"
                     /translation="MEKRGYIEDIFGHYTRYGQRYVTDSSIMESSDVYELVQDISNQV
                     ALATPIVIGPDGNEVKDHHLLNILKSPNDYLTGFEFTKLETNTLLINGETFPLTDRDQ
                     LHLAYGVTTKINERLQEEFEMNGQKIPGQMIRHIKNIGTDSLKGAGIIDLARNTLEGV
                     LSAEKVLTDKYTKGGLLAFMLKLDAHINPNNSAQTKIVKAILDQLEGTQNESDHSVKM
                     IPLGKGYSIETLKSPVDDAAILNYLGVYKKDLGKFLGINVDTYQSLMKTDIEKAMMYL
                     HNKAIKPILKNKSEHYTALFFMPNSGYRVEWKINILDFVPYSTKTNIGYNIVRTGITS
                     PDNVAEMLGFPKQNTPETQAIYISNDLSRIGQKNATDDSLPTNDQDLKGGDGNEEEGN
                     SHD"
     gene            75761..76330
                     /locus_tag="ACG8LA_000100"
     CDS             75761..76330
                     /locus_tag="ACG8LA_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA];
                     GO_process: GO:0019082 - viral protein processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 family phage prohead protease"
                     /protein_id="HFQ0202442.1"
                     /translation="MKKKEIRTIDITNLSTRSDEETHTRTISGYAAVFNSQTLLWDDL
                     SEVIVPGAFSKAISNSDVRCLFNHDWSNVLGRTKSGTLRLEEDERGLKFEVDLPDTTV
                     ARDLVKSMERGDINQCSFGFVPTEETWDYNSEPMLRTIHEVELYEVSIVPLPAYEDTE
                     AALRSRDELEKNVEERKKLIKKINQALEA"
     gene            76343..77707
                     /locus_tag="ACG8LA_000101"
     CDS             76343..77707
                     /locus_tag="ACG8LA_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016622740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HFQ0202443.1"
                     /translation="MDKELLKKMKARREQRLTELREKVESGELREADLEAVKEEIDSV
                     IDELNGIKDELGADSGTDETDDNTDDQSNSTDSDESRSGEDNDQEEDSDSEDSSENRS
                     GMITQQQRDGLLGSIKNGLEARAKMTKKQKDQQLRKAFANFVAGNISEAEARALGIEA
                     GNGSVTVPEVIASEVITYAQEENLLRKYGTVVRTSGDVKYPILVKKADANVNKKERST
                     DIAETAIQFDEILLNPAEFDALATVTKKLLKMSGVPVEDIVVEELKKAYVRKEINYMF
                     NGDDAGNENPGALAKKAVAFKKPLDLTASGAGQKLYDALIEFKNTPVTEVMKKGRFII
                     NRAALTAIEKMKTDDGFPLLRPFTQAEGGIGYQLVGYPVDWTDAADKKGEPDTPVLYF
                     GDFSAFKIQEVIGALEIQKLVEKFSGKNQIGFQIYNLLDGQLVYSPFEPAVYRYEITK
                     PVGG"
     gene            77709..77987
                     /locus_tag="ACG8LA_000102"
     CDS             77709..77987
                     /locus_tag="ACG8LA_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="head-tail connector protein"
                     /protein_id="HFQ0202444.1"
                     /translation="MEEQTKELSLEEKFKSHIHFEEGMDDSLLSFYLNMAKDYVKTAT
                     GGQQEYLILMVAGIAYEYRVSEDELDKAMNAMTPFIVQGAIQNAEETD"
     gene            77968..78294
                     /locus_tag="ACG8LA_000103"
     CDS             77968..78294
                     /locus_tag="ACG8LA_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HFQ0202445.1"
                     /translation="MPKRQTNNLRWKAELLDIKTGTDGNDRPTTIYEFKRLIFYEELG
                     VTSQEKYLSQQAKTDVVRRIKVRWDKSITEKLSALKIDSVTYNITRIYTNPDAREMEL
                     SLAYVD"
     gene            78284..78622
                     /locus_tag="ACG8LA_000104"
     CDS             78284..78622
                     /locus_tag="ACG8LA_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202446.1"
                     /translation="MSISFDELKTALKSTKLAVFRDKARLGTMYPYIVYSNVSNSKKM
                     ASGKVYKKLPYYQVSFFTLGTEQDLVVIEQALQNAGIPYSDFTGIQGDENDDTVTNYY
                     TYVRCVENAK"
     gene            78612..78977
                     /locus_tag="ACG8LA_000105"
     CDS             78612..78977
                     /locus_tag="ACG8LA_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97-gp10 family putative phage morphogenesis
                     protein"
                     /protein_id="HFQ0202447.1"
                     /translation="MPSNKNGFSEISDYLGNLSKVDPKKLSLESLEEAANFYLKQLLP
                     NIPKSLLKKKHMRDQIKVVVENDQVKVQFEETAFYWRFAENGTTNQRAQHFASGTYEQ
                     NKEKIEEIMTRKILDLWEG"
     gene            78984..79610
                     /locus_tag="ACG8LA_000106"
     CDS             78984..79610
                     /locus_tag="ACG8LA_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HFQ0202448.1"
                     /translation="MGKQDTFYFEGLDDILIAMMATPDSVGTAPTYSEVLRLPIATKI
                     GVKGNGTALEKWASSKMFRRVSRETKHELALDHVGIPIEVMDEIKGLVAKSGVTFSKN
                     TAREFPYFAFGFIGNIENGGKKAVWYPNTQLSNVIDEEYATAEEETKIDDVTANLVSI
                     GLKYNNVMYASFDSNRDGASLELFNKFIAQPVYDEEQWKTLAKVGGAG"
     gene            79610..80074
                     /locus_tag="ACG8LA_000107"
     CDS             79610..80074
                     /locus_tag="ACG8LA_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202449.1"
                     /translation="MARLSDYGIHVEDLKNSAVVIIQGAEFPISFTMQTMEFIADVYG
                     GDYSQFESDMNAMLSKKEGQISSANLSPSDLKIMRALIYAMLRTGGLEEDPETIFKFL
                     GMSGEVLSAYSTCMEIFASQTFQVEDLKKSKKPQDFQKAQAKRKKNKKNRKR"
     gene            80269..82578
                     /locus_tag="ACG8LA_000108"
     CDS             80269..82578
                     /locus_tag="ACG8LA_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HFQ0202450.1"
                     /translation="MAGKESDVVLNFKTNGEVSYSKTIKEINKEMNLAAAEYKNQVSA
                     MDKDATQTEKLRAAKQKLEKQLGLAEQRSQMLREEYEKSVKETGEYSAESEKLYKQLL
                     NSETGENKLRTALEQTNDALKEQGDVSVDTAKKLQKIEETGEKVKGVGEKMSVGVTAP
                     IVAAGAAGLAAFGEVDEALDTIITKTGATGDQADRLSQSFKNVGSNTHLPLQTVGEAI
                     GEVNTQFGFMDKKLEDSTNYLLQYAEINDTDVSQSAISARQAIDAYGLEYDDLNSVLD
                     VTTKTSQNTGQSVDDLMQKAIDGAPQIKQLGLSFGEGVTLLGQFEQSGVDSSAALSSL
                     SKATVAYAKDGKSLSQGLEELQDKVKNAGSETEAINAAAEVFGTKGGPRMADAIRRGT
                     LNLEDLAKTAGESGGAVGDTFDATLDPIDQADQAMNNAKLAMADVGEAVQVSLLPFFE
                     KATSLLQEFSKWWGSLDQDTKNWIITIAGIAAAVGPVLIVLGSLMGSVTKIVGEVKSF
                     IGVWQGLAGLFGMSGGWFALAVIAIGALVTGLIWAYNNVKWFHDGVNSFFKGVSDVAV
                     EIFNFLSGYFGGFFDGVIANFNNFYNAGKRIFSGFLDFITGVFTGNWSKAWQGLVDIF
                     GGIFDGIVAVGKAPINAMIGLINGFIGGLNNIKIPKWVPGVGGKSFSISKLPYLAQGG
                     HLINGQAIVGEAGPELLTAKNGKTTVTPLSDEEKRKGISGRVSGGSIEQHIHIGKVDA
                     NNPSELDRMNRKFAKANKQAIRDLGGVPI"
     gene            82590..83294
                     /locus_tag="ACG8LA_000109"
     CDS             82590..83294
                     /locus_tag="ACG8LA_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HFQ0202451.1"
                     /translation="MNPDEPNFIWKNRNAVIDMNCIIEAELPDIMPNKRYETYTIQGR
                     SGELTETFDDYEPFDLEIEGITIPHSKLREVKRWLTGKSQLITHNDPDKYLEAICSMD
                     KEVPFENEWGFFYTFDVTFRCQPLKRKIGEAPKIFHSSVMDIFDHGDEIAHPYLEIES
                     NGGDITIAVGDKSLTILNTLAATIVVDTQLGKAIQEGLNLFTRGDWPVLQPEWNQVKI
                     SGKFKEVRFWNRSVYL"
     gene            83291..>85421
                     /locus_tag="ACG8LA_000110"
     CDS             83291..>85421
                     /locus_tag="ACG8LA_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail spike protein"
                     /protein_id="HFQ0202452.1"
                     /translation="MTQEFIYAYKKMPDDLSVNGASLVDWEDLPEINRVLNGQYRFYG
                     NYSRSGQYRSYLKKGNFIKAKVPDGSWQYFEIYNVKKNLTSVSVTARHIGFMANKNFI
                     VKSFTDNGNGSQIMTNLKNSLAFDQKFNYLSNVGTTHQFTARQVAPVEAIIGSNNGNQ
                     NLTGVTSAELDMDNYDLKLVKQIGSDNGFRIDFGINLEAIEEEIDEESIVNSLYLVGG
                     VPDNDYDEDKEPIEYGYLEIDGVTNENRRIAKRENGDCKTVDELIKWGKTLFDNDRIH
                     EPKATHTVSMVALEHTLEYGDMYQELASLHFGDVAHVRAKELDIEIKERMVEYTYFPT
                     LGKYKDIVLGNDLSLYTSAVNTQAQELKKKIDNRTETLVQNVLNATAWITGNSGGHVV
                     FRPEKAPSEILIMDTPNVANAKRVWRWNLNGLGYSDNGVNGPFGIAITSKGEIVADFI
                     KVGTINAEVFETSFNAYGDVLKLVKGTLQIWNENKKIMELTKKGMEFWNRKESIGTIG
                     TTDSAGNPFPNAVTPTPLEENSLVIRTNGDGKYILISPTAEKGFVLLGNGKAYYFGDL
                     DIQGKLTVRGKEVIPGQNGGPSGGGETPGGYPDELKTDAEKRAWRIYDILCNNGFTKQ
                     SACGILGNIQQETGGTFDPDTVQIGGPAYGLVQWDGSSYPLVGPATWDGKVYVQNLFN
                     AAGIKEPITSLDAQVRLLIWTFTNGQWM"
BASE COUNT        28795 a        14045 c        17947 g        24634 t
ORIGIN      
        1 gggtaaacgt tttttaaact aacgtcaatt atttataata aaaaatgaga taaagatgag
       61 gaaatagaat tagaaacata taattattaa agggaaacat ttttacagct ataatttgaa
      121 aaaatttatc gttattatat gattaagaag gattgaataa agaaagaagt tgaaaacgat
      181 acctgattac aaaaaaataa cttttataag ttctataacg ttgattatat ttttaattct
      241 tattcttctc gtcgtcttgg ttccccgaat ttttggtttg actccttata ttattgagga
      301 caaagaaatg agtccatatt atgcacaagg aaatctgata tatgtacgac cgaaaaatac
      361 aaatgagatt ttagtcggag atattattac atattatgaa aattcaggaa aaaaaatctc
      421 gacgcgtcgc gtaatagccg ttgaaaacaa ccacgaagat ttttatacaa aagctgatac
      481 aaagacttat attgagcctg gagtagtaaa aaagagaaat attatcggta gtcccatctt
      541 tcagattcca tatattggac tagtcctttc aaaaacggca tttgcatgga ttcaggggtt
      601 attctttacg attgcttttt gcctaacagg aatcacagca tggaatacct ttgtagagtt
      661 gaaaaagaag cggagacgaa cacagaaatt tttgtaagaa tgttaaaaac ataaatgtat
      721 tccagagatc caacgactct tctgaacatg aaacacgaga aaacactcat gcagcttgta
      781 gatttagtca gttgttcgta taatgtgtga agaggaggag tagtatgcgc aatgaaatga
      841 tgcatcgtcc tgtagtcaaa gaagaactat tggattttat gcgtacccag caaaaaaaat
      901 taccgggtga gctaggcaaa ctggaagaag aagctcatgt agcagaagta ccagttattc
      961 cccatgaaac agttgtattt ttgaaatttt tacttggaca gcttcagcct gaacgaatct
     1021 tggagatcgg agcagctatc ggtttttcat caagtgtcat ggccacgaca atcggagaaa
     1081 acgctcatgt tacgacaatt gatcgtttcg atgtcatgat cgagaaagct aaaaaaaact
     1141 atgaacgtct aggactgaca gataaagtga ctttgcttga aggtcaagca gcagatatct
     1201 tgccggagtt gtctggtccg tatgacttta tttttatgga tagtgcaaaa tcaaaatata
     1261 ttgaattttt acctgaatgc ttacgtttgt taagaaaagg tggcgttttg atggtagatg
     1321 acatcttcca aggaggaacg atcttgctcc cagatgaaga gattccccgt ggcaaacgag
     1381 ctatccatcg taaattaaat gaatttcttc gtgttgtgat ggatcatccc gatttgacat
     1441 cgacaatctt gccattaggt gatggtgtga tcttaatgac aaaggaatca gaaacaatcg
     1501 agttgtgata catgattatg gcagcctgta gataatcgat tgaatcgagg gctcaattcg
     1561 aacttgatgt aaaagtttct atatttgtaa gtcaattaaa ggatacagga aatctaaata
     1621 aacaggagta gcatgaagtc aatgtagctc ctgttttcaa ttgataacct tagaacagct
     1681 gaaggagaat gtctcgtttt aaaagattga tttagtagtt gggccaaaat aattcattat
     1741 ttgctaatta aataactatt tcgtattgac agaagcaatt taattatcta taattattga
     1801 tgttccgctg attcttgtca tagtagctca gctggataga gcatccgcct tctaagcgga
     1861 cggtcggggg ttcgaatccc tcctgtgacg ctaaaaaacc gttagaaact gaggtttcta
     1921 acggtttttc tttgtttttt gtgccaatat tgtttgtttt caaaggcaaa taaaataaaa
     1981 aaacatcctt atcgagtaca attataagga gcaaaaaaat aaaactcatc agaaaagagg
     2041 aagaagatat gacgatacta tctagaattt tagtgactct agttgcaatt gaattttttt
     2101 atatcatgta tatcgaaacg gtgagaactg attctgacac gacaagtagg gtttttaaaa
     2161 tgagtaaaga agagttaagc agaaaatctg ttcaaacatt gtttaagaac caaggagtgt
     2221 acaatggact attaggagtg ggactacttt atggagctta tctttcttcc gcatctaaag
     2281 aaatcacaag tatgctatta atatctattt tttttgttgc attatatggc agtttgacta
     2341 gcgatcgttg gattttactc aaacaaggtg ggctagctct gttggcattg ctttctattt
     2401 tcttataaat atagaaaaaa taagaattta tctaacagga aactttgtga aaaatattac
     2461 tttatctcat gaaatatgat attctaatga atggtatttt agaaaatttc atgaaaaagg
     2521 agttagatag gtgttcaaaa attatgtttc ctcactaaaa aaagaatttt caggttatga
     2581 tctttcaaga tttcagaaag atcttttggc tgggatcaca gtagctgctg tagcattgcc
     2641 tttagccttg gcttttgggg tatcaagcgg agctgatgcg gccgcaggtt tgattacggc
     2701 tatcattgcc ggtatcgtta ttggcggttt atcaggcggt ttttatcaaa tatcaggtcc
     2761 gacaggtgcg atggcagcta tcttgatgtc tattgcggca acaaagggaa tgcaaggtgt
     2821 attgcttgct acttttttag cgggtctatt tttacttgca gcaggacttt tccgattagg
     2881 aacactgact tcttttatcc cagcacccgt aattacgggg tttacttcag gtattgctat
     2941 cattattgca ttaggtcaga tcgataattt atttggtgtt cactcggaag gtacaaacgt
     3001 tattgaaaaa ctaagtagtt atcaaacgat aggatttccg ataaacacag cctctttgat
     3061 catgggaggg ctagtcattt tagggatgtt tatctatcca aaaaaatggg cgaaacgaat
     3121 gcctagttcg ctgctggcta tcattttggc aacagcagtt atgctattgt tccatttacc
     3181 agtagcaact gtgggtaaga ttccacaaac attgatcagt agtaatcgtt tgaatatggg
     3241 agattttagc ttttctgcct tgcaacaagt ggcagttcca gctattagca ttgctttatt
     3301 aggaatgatt gaaagcttgc tatgtggtgc ttcggctggc cgaatggcaa ataagccctt
     3361 agatagcaat caagaattaa tggcgcaagg aattggaaat ctgttgcttc ctttctttgg
     3421 cgggattcct gctactgcgg ccatcgcccg tacaagcgtg gccatcaaat ctggtgcaca
     3481 aactagatta gctggtatga tacatgcagt tgtcttactg ctctccatgc ttgtttttgc
     3541 gccagtgatg tcacagattc caatgccagc acttgcaggt gttttgattg tgacggcttg
     3601 gcgtatgaat gaatgggaaa cgatcaagga gctatttact aataaatatt ggtcagcagt
     3661 tctattgttt atccttacga tgatttgtac agttatcttt gatttaagta ttgctatcgt
     3721 gatcggggtg atcggcggct gtgtattttt tgttgtcaaa agcgctgcta tcacgatttc
     3781 attagaaacg atcgattggc aaagaatggg gctgccagaa acggaaaagc tgaataactg
     3841 gacagtagtg tatattagtg gtccactgtt ttttatgtct tcagaaaaac tcaaaaataa
     3901 attggaagaa ctaaatcatc acgatggtgt cattttctcc atgcgaggcg taccaagtat
     3961 tgatttgacg gcacgtgcag tttttgatga atttcaagaa aaagcagagc aaagaggaca
     4021 aacgattatc tatacttcct tgcagccaga agtagaaaaa caactttctc acttgtggga
     4081 acatacattc acgcatcaac atcaaacagt tgctcatgcg ttgacagctt tacatgcgaa
     4141 atatactgca attagccatt aaaacaatga aaaagaacag acaagactgt aaactgaaga
     4201 ttttatggtc ttgtctgttc tttttaatat tgctgtaaaa gtgaagctag tacttgccag
     4261 tcttgatgga taacaggtac aagggagcga ttgtagaaaa tagctgctgg atgaaaaagt
     4321 ggaagaattc gatagttttt ttctgaccat tcgtaggcat ccttttgttc tgttaattgt
     4381 aagacaggcc ctgtatagag ttgaccatga tttttggtaa ccgtatattc tttgccaagt
     4441 aaacgttgaa gaccaatgtt tccaagtgtc gcaattaatt ttggctggac cttcatcagt
     4501 tcgtaatcca atattggtgc atgcgcaaat acttcggaac gagtaggtgt ccgatttgga
     4561 taaacagttt ctgactgttg tgtccgttta ttgatccgat gagtcacgcg atacgggcgg
     4621 ctccttacag cactggtgat atacacctct tctcgtgtta agccagttga agaaagtgcc
     4681 tgcatcaatt cttttccagc ttgaccgcta aaaggaacat gcgtatcaat ctctgttttc
     4741 cctggggctt ctcccacgag catcagttta ggatgaagag gtccttgccc agcgataaat
     4801 ccttctacag gacggccgtt cattcttaaa gaagcttctt gtatcagttc ttttgggtat
     4861 tccatttatg ctcctccttt ttcttttatt ataagaataa aagaaacaca atgcgactat
     4921 tttatttggt agaactgtga ggatagaaaa gcagaagtat tgcttgaatt tttgttttac
     4981 tttttgattt taaatttagt tgactaacgg ttgctgttct ggtaagctag tactgttgta
     5041 attgtggact ccacagctac aaccgctcag aacaagtaat aagcacagca tatgctgtca
     5101 cttcggatgg cgagtctaag tatatcagaa ggaggtgctt tatagcatgt acgcaattat
     5161 taaaactggt ggtaaacaag taaaagttga agtgggacaa gcaatctatg ttgaaaaact
     5221 tgacgttgaa gcaggagaaa aagttgtttt tgacgaagtt atcttagtag gcggagaatc
     5281 tacaaaagta ggcgctccaa ctgttgcagg tgcaactgtt gaaggtactg ttgaaaaaca
     5341 cggcaaacaa aagaaagtcg ttactttcaa atacaaacct aaaaaacatt cacaccgtaa
     5401 acaaggtcat cgtcaaccat atacaaaagt ggttatcgac gcgatcaacg cttaatagcg
     5461 tttgagaaag aaggcctata tatgatcaaa ggaacattta agcgaaatga cgcaggtcag
     5521 atcgtttcat tcactttgac cgggcatgct gatgctggtc cttatggaag tgatatcgtt
     5581 tgtgcgggtg tttctgcgtt agcgatcagc actgtcaacg ggattgcctc attagccggt
     5641 tttgagccga ttgttgaaat gaatgaagaa gaaggcggtt atctttatac cgaagtcact
     5701 tcaggaatga cacaagaaca aaacaatatt gctgagattc tattagaaaa tcttttatta
     5761 ggattacaat cgatagaagc tgaaaactca gaatatatcc aaattaaaac aattaatgat
     5821 aaataggagg tgcagaccat gttgttatct atgaatctac aattatttgc ccacaaaaaa
     5881 ggtggcggtt ctacatctaa cggccgtgac tcagaatcaa aacgtctagg tgctaaacgt
     5941 gctgatggac aaacagttac aggtggatca attctttacc gtcaacgcgg tacaaaaatc
     6001 tatccaggtg taaacgtggg tatcggtgga gacgacactt tatttgcaaa agttgatggc
     6061 gtagtacgtt tcgaacgtaa aggccgtaac aaaaaacaag tgtctgttta tccagtagct
     6121 caagaagctt aattgaatct tatgattaaa gaggttgtga caagactttt gtcacagcct
     6181 tttttgttta taaaaataaa agttgtagtg gaggctacga agtttacttt gtctttttac
     6241 acttaatatt tttttgccaa tttggaatca ggatgttttg ataactatcg ttttcaattg
     6301 atggaagcta tattgtttgc tatcagtgaa ataattatat ggtaaacagt gttctttttc
     6361 ttgtttccat tataaaaatc gtatcgggat ttttcgttct tttaaattga acatttctat
     6421 ctatccgcgt gttatcaaca aaacaaaatc aggtaaatag ttgacgaaac agaaataaat
     6481 acatagtatt atgttttgaa gcctaagtac aatagtctat agaaaaggag cgataccatt
     6541 ggcaaaacgc attgaccgaa tttatatgta tgtcaaagaa aaaaccgctc atttaacaaa
     6601 ggcagaatat gatcaaggag taacaacaca ggaaattgct gaagtgttag ggattcagcg
     6661 aacaaatagc agtaaagatc tgaatcagct agtgcgcgaa ggaaaactga taaagacaga
     6721 cggacgacca gtacgttaca tatatcaaac actcgttacg cacgtaaagc cagttacaaa
     6781 acatgtagtc agttacaaag aaacgccggt ctctgaagaa aaaaatacac tccaaataga
     6841 tactaaggat atctttgcaa aaatcattgg agctaacggc agcatgaaaa attcagtgga
     6901 acaggcaaaa gctgcgattt tgtatccgcc aagaggatta aattgtttga ttacaggacc
     6961 taccggatca ggaaagactt attttgcaca cgcgatgtat cattttgcaa aagcgcatca
     7021 tgtaatagat gaggaaacgg aactgattgt tttcaattgt gctgattatg ccaataaccc
     7081 tgagcttttg atgagtcatt tatttgggta cgcaaaaggt gcttttacag gcgcagatga
     7141 agaaaaaatg gggattatcg atcaagcgga tggcggtatg ctgtttttgg atgagattca
     7201 ccggttgccg cctgaaggtc aagaaatgat cttttacttt atggatcatg gaacttacag
     7261 tcgtcttggg gaaacaacga aatcccatga agcaaatgta cggatcgtag gtgcgaccac
     7321 agaagaccca ggttcttctc tattagaaac ttttgttcgg cgtatcccaa tcaatatcaa
     7381 acttccggct tttgaaaaac gtcctgcaaa tgagaaagtc gatttagtaa aaatcatgat
     7441 tgcccacgaa gcaaaccgca cgcagcgaaa gatttctttg acagaagatg tagcaaaagc
     7501 attgatcggc agtgtgacct atggaaatat aggacaattg aagtcaaata tccagttagt
     7561 atgtgcacga ggatttctaa atcatatgca atcacccgaa atctcgatca caatcgatga
     7621 tttgacagaa gggattcgta gcggattgat tcaattagca agcaaccgca gtgcaatggc
     7681 agagctttct aaaatattgg agccaaagat aactgtagca ccaaatgata cgatcatgaa
     7741 aatccaatcg gactcctatg agttacctta taatctatat gatatcatcg gagataaagc
     7801 agctttactg aagtcggatg gtttggatca agaagcaatc aatcatttca tttctacaga
     7861 tatcaacatc catctgaagt ctttctataa agaccatggt ttttctttta atgcagacag
     7921 caaattagca gaatttgtag atccgaaaat catagaagtg accaatcaga tttatgtaat
     7981 ggtcaaaaga tctttaccat atgagtttca gcaaaacttt atttatgcta tgagcttgca
     8041 tatcagttct tttttgaaaa aaatcaactt aggagaagaa cggcatacga atgataacat
     8101 ccgtgagatg gcttttgatt ttccagatga atatgctgtt gcgaaagaag tgcgtagtta
     8161 tatcgaaacg tattttcaag tggagattcc agaaagtgaa gactattact tgaccgttct
     8221 actcgtctcg ttacgggcaa atcaagcaag cggcagaatc ggtgtagtcg ttgcagctca
     8281 cggaaacagc acagcaagca gtatggtcca agttgtccaa cagttgttag atgcagagaa
     8341 cgtacgagca gtagacatgc ctttggatat ggatccgaaa acagcattgg accgaattga
     8401 acgcaatgta caagaagtag atgaaggaag cggggtcata ctcttagtag atatggggtc
     8461 ccttgcgtcg tttaattcgc aaattcaaag agacactgga attccagtac gtactgttga
     8521 tatggtaaca acttctctag ttttggaaac tgtacgaaag gtctcagtat tagggacaga
     8581 tctagatatg ttgcatgaat cattgaaaaa ttttcgaggt tacgcagaaa tatcttctgt
     8641 agaatctgtt caggaagcaa aacctattca taagaaaaaa gctgttttgg ctatctgcgc
     8701 atctggcgaa ggtacagcac aaagaatcaa agaattgatc gaacgagcgg taaacaagcg
     8761 tcaagaaaca gaattagaag ttctagcttt gtcgattgtg gaagtgaaag aagaactgcc
     8821 agttatccaa aaagaatatc agatcatagc tactactggg attactgatt tgaatatcca
     8881 agccccattt attcctttag aacgttttat tgatcaaaat atcgaagtca ttttggatca
     8941 gttgctgatg gaatcagaat tggaggaaac tgaattcatc tccctagatg aagagtcagc
     9001 taaaaatacg tgtgttgagt ttatctctga taacttcatc tttattaatg gtagtaagtt
     9061 aatcgatcca atgtggcaat tttctacaca aatctctcag acgacgggaa tcggcgatga
     9121 agaatatgga ttcaaaatca acctagtgat gcacacagca ggaatgatcg aacgtattat
     9181 tcggaatgaa ccattgactg tggaagaaaa cgaattgaca aatacaacga atgatcctct
     9241 ttatagccaa ttggcagcct cagttgttct gttggaagat cagataaaag taaaagtgcc
     9301 gatagaagaa atgtattatc tgctacgtct agtccataat cagttagata aaaaagaata
     9361 cactgtgcca tgaatacaca aaaacgatac acttttatag tgtatcgttt ttgtgtattg
     9421 gttaagaatc ctttaaattc aattagtgta tcgtaaaaaa gttggcacgc tttttgctta
     9481 tagtagtgtg tgctaggagg tggttgttca cacagaaatg ataggggttt ctgtgaagta
     9541 gtgaggaaga aggagttttg cagatggata ttcgattggc acgtatagat gatcgtttaa
     9601 tccacgggca agtcgcaaca gtttggtcga agcaaacagg tgttgaacgt atcattgtga
     9661 tcagcgatgt agtcgctcaa gataaattga gaaagtttct actaaaagaa gctgcaccgc
     9721 cggggatcac agcaaatgta ataaccgtgc agaaaatgat tcaaatctat catagtggat
     9781 tattatcacg agcaaaagtg atgcttttat tcaccaatcc ccaagatgtt gaagcggttg
     9841 tccgctgcgg tgtacagttg aagtcgttga atatcggcgg tatgagtttt actgaaggca
     9901 aatcaatgat taccaatttt gtttcagtaa atcaacaaga tattgattcc tttcgttact
     9961 tgaacagtca agaagtggag ttagagattc gaaaagtacc tgctgacagg aaaatccttt
    10021 tgatggaact actagcgaaa atcaaaaagg tgtagcaaga atggttgttg gaaaaggtca
    10081 aataattctg ttgtaatggt tagcaattat taatattttt gaatttgtta caacaaaagt
    10141 aaataggagg tataaatatg gtagggatta tcctagcaag tcatggacaa tttgctgaag
    10201 gaatcttaca atccggttca atgatctttg gcgaacaaga aaacgtcaaa gccgtgattt
    10261 tgaaaccaag tgaaggtcca gatgacttga gagccaaatt ggaagaagcg gttgcttctt
    10321 ttgataatca agacgaagtg ttattcttag ttgatttatg gggcggaaca ccgttcaatc
    10381 aatcaaacac attattcgaa gagcacaaag ataaatgggc aatcgtcagc ggtttgaatt
    10441 taccaatgtt gattgaagcc tacgcatcac gcttttcaat ggaatctgct catgaaattg
    10501 cagcacacat cattgaaaca gcaaaagacg gtgtaaaagt aaaaccggaa gaattagaac
    10561 cggcagaagc accgaaagca gcagttgaag acgcacaacc taaaggagca cttccagaag
    10621 gaactgtggt cggagacgga aaaatcaaat atgtattagc acgtgttgac tcacgtctgt
    10681 tacatggaca agttgcgaca gcttggacaa aagcagtgca accaaaccgt attatcgttg
    10741 tttcagatgc agtatcaaag gatgatctgc gtaagagact aatcgaacaa gctgctcctc
    10801 caggtgtaaa agcaaatgtt attcctatta gcaaaatgat cgaagtagca aaagaccctc
    10861 gttttggaaa taccaaagca ttgcttttat ttgaaaatcc tgaagacgta ttgacagctg
    10921 ttgaaggtgg cgtagacatc aaagaattaa atgttgggtc aatggcgcat tcggtcggta
    10981 aagtcgttgt aagtaaagta ttgtctatgg gacaagaaga cgttgaagcg tttgagaagc
    11041 ttgaacaaaa aggtgtgaaa ttcgatgtac gtaaagtacc taatgattca cgcgataaca
    11101 tggatgatat tttgaaaaaa gcaaaagctg aattagcaaa agcgtaataa ataatattaa
    11161 aatttatagg aggcttatca tgtctattat ttcaataatt ttagtcgtat tagttgcctt
    11221 tctagctggt atggaaggta ttcttgatga atttcaattt catcaaccac tagtggcatg
    11281 tacattgatc ggtttagtta ccggtaacct cgaagctggt atcgtacttg gcggtacgct
    11341 tcagatgatc gctttaggtt gggcaaatat cggtgccgct gtagcaccag atgctgcatt
    11401 agcatcagta gcatcagcaa ttattttagt tttaggtgga caaggtgtta aaggtgttcc
    11461 ttctgcgatc gcgattgccg ttcctttggc tgttgcaggg ttgttcttaa caatgatcgt
    11521 acgtacaatc gctgttccaa tcgttcattt gatggatgcg gctgctgaag aaggaaacat
    11581 ccgtaaggtt gaaatgtggc acatcattgc tgtatgttta caaggggttc gtatcgcggt
    11641 cccagcagca gcgttgctat ttatcccagc acaaactgtg caatcattcc ttgaatcaat
    11701 gccagcatgg ttaacagatg gtatggctat cggtggggga atggtcgtag ctgtaggtta
    11761 cgctttggta atcaacatga tggctacaaa agaagtatgg ccattcttcg ttattggttt
    11821 cgttgtagct gcaatttctc aattaacatt gattgctcta ggtgctttag gtgttgcatt
    11881 agctcttatt tacttgaacc tttctaaaat gggtggttca tcaaataatg gaggcggaag
    11941 caactctggt gaccctttag gcgacatttt gaatgactat taatcttgaa ggaggaaaat
    12001 aaaatggcag aagaaaaaat caaattatca aaaaaagatc gtttagctgt tgcgtggcgc
    12061 tctaccttca ttcaaggttc atggaactac gaacgtatgc aaaacggtgg ctgggcattt
    12121 tctatgattc cagcaatcaa aaaattatac aaaacaaaag aagaacgttc tgcagcatta
    12181 aaacgtcact tggaattctt taatacacac ccatacattg cttctccaat tttaggggtt
    12241 acattggctc tggaagaaga acgtgcgaat ggcgcgcctg ttgatgatgt agcgattcaa
    12301 ggggttaaag taggtatgat gggtccttta gctggtgttg gtgacccagt gttctggttt
    12361 acagtacgtc caatgctagg tgcactaggt gcttcattag ctatgggagg aaatatcctt
    12421 ggaccaatca tcttcttctt aggttggaac attattcgtt gggcattcat gtggtataca
    12481 caagaatttg gctacaaagc tggttctaaa attactgatg acctttctgg cggattgtta
    12541 caagacgtaa caaaaggtgc ttcaatttta gggatgttcg tattagctgc ccttgtacaa
    12601 agatgggtat caatcaaatt cttaccagtt gtatcaactg taaaattaga taaaggtgct
    12661 tacatcgaat gggataaatt gccttcaggt ggtgaaggaa tcaagagtgc atttgaacaa
    12721 gttaataatg gcttagccct ttctcctgaa aaggtaacaa cattacaaga caacttagac
    12781 caattgattc ctggtttagc tgcattagga ttaacattgt tatgtatgtg gttgcttaag
    12841 aaaaaggttt ctccaatcgt tatcatcctt ggtttattcg tagtcggtgt tgttggacac
    12901 gtcatcggac ttttataatc cataaaaata tagctcgggc gttgtcccga gcttttttta
    12961 tatagtatac tgttcataaa caaatatctg gagggagaaa atggttcaat caatcaatac
    13021 aaaagtagac ttggtaattg atgctacttc gtttacgggt ctgacagatt acgggcaaat
    13081 catgataggt aataatggtt ttgagtttta ccatgcgcga gatagacgca aatatatcca
    13141 aattccatgg gaagaagtgg attatgtact agcatcagtc atgctaaagg gaaaatggat
    13201 tcctcgatat gccattcaaa cgaaaaaaaa tggtacatac acattttctt ccaaagaacc
    13261 taaaaaagtg cttcgtgcga tcagagaata tgtagatgaa gatagaatgg tacaatcatt
    13321 gagtttcttt gatgtagtga aacgtggtat tcgtagtatg tttaaacgca agtaaaaaat
    13381 aaagaaaact tctaagagga ggttttcttt atttttttac tttgcagaag aaaatatgaa
    13441 atagcaaaac caattatttg tcccctttaa atcccatatg ctaaaattga ttagcaaaga
    13501 aggaggttat attatgagtt ggttatggac attgattgtt ggagccgtga tcggagcaat
    13561 tgcaggtgcg atcaccagta aaggaaattc gatgggctgt gtaacgaata tcattgctgg
    13621 actagtcggt tcaagtattg gacaagcgat tttcggcgaa tggggaccaa aagctgcagg
    13681 tatggcactt attccatcta ttttaggcgc agtgattttg gtagcagttg tctcattttt
    13741 ctttggaaaa cgatcataag tttttacaaa atagtaaact aaaaggagtt gcagcgagac
    13801 tgtgactcct ttttggcttt atttatttaa aataaaaaga agttttccgg aaatttttat
    13861 ttaactgtcg tgtacgaaga aaagtttgct ataatggaaa aaagcgtgca aagaaagagg
    13921 gagtttcatt atgatgctac gtgtagaaaa attgcgcaaa aaaatgcaag aagaaaattt
    13981 ggattcattt ttggttacca gtccgtacaa tcttcgttac ttaacgaact ttacaggtac
    14041 gacaggatta gctgttatta ctttggaaaa agcatttttt attactgatt ttcgttatac
    14101 cgagcaggcg gcagcgcagg ctcaagggtt tgaaattatt aaaaatgtcg gacctatttt
    14161 tgatgaggta gcaaacttag tacgcaaaga agaactgcac tcattagctt ttgaggaaac
    14221 aacagtctca tttttagaat attcggtttt agaagaaatc atcgatgcgg aattagtacc
    14281 tgtttcacag atgatcgaag aactcagaga agtgaaagat gaagaagaaa tcgctattat
    14341 cgaaaaagca tgtcatattg cggatatggc atatgatcac atcctgaaaa tgatccaacc
    14401 gggcatgact gagattgaag tcgcaaatca actagacttt tatatgcgtt ctcttggcgc
    14461 ttcaggtgtt tcttttgata cgatcgttgc tagcggattg cgttcggcta tgccgcatgg
    14521 tgtagcaagc aaaaaaatca tcgaacaagg tgacttgatc acattggact ttggttgcta
    14581 ttacgaaggg tacgtttccg atatgacacg tacattcgct attggtgatc ctggggaaaa
    14641 attaaaagaa atttatcaaa tagtcttaga tgctcaatta gcagttattg atgctgcaaa
    14701 accaggaatg actggtgtcc aattagatgc agttgctaga gattatattt caaaacatgg
    14761 ttacggggaa gcatttggac attctacagg acatgggatc ggtttagaga tccacgaagg
    14821 accaaacgtt tcttctcgtg cagaaaagca atttgtacca ggaaatgtga tcactgatga
    14881 accagggatc tacttaccag gaatcggtgg agtacgtatt gaggatgact tgttgatcac
    14941 agaagatgga aatcgtgtgt tgactcgttc accaaaagaa ttgatcatct tatagtttca
    15001 tcaatagaag aagtaagcgt aaaaatcagt gttcacagac tttgttatag aaaatcactc
    15061 gatttaatga tacactatag aagaactttt aagctgtaag agataataaa gttgggtgtt
    15121 ttctccaatt catagcagtt tgcagctgat cggcggcagt tttcttacca cgtgatcact
    15181 atgccgcatc atagagaatt cggatgtatc tcgtgcttag gcaaagggag gaataaataa
    15241 atggcagatg aaaaaaattt gattttaaac gcaaaccaag atttaggaga gatcgtgatc
    15301 gctcctgaag tcatcgaagt aattatcggg attgcagctt ctaaagtaga aggcgtatac
    15361 ggaatgcgcg gaacttttgc cagcaatgtc actgaattat taggacgtgc agctcacgga
    15421 aaaggtgttt acttagcaaa cgaggaagat ggcttgaaag tagatcttta ctgttatcta
    15481 gaatatggtg tttcagttcc taaagtagca atggaaatgc aggaacgggt cagccagcaa
    15541 gtccttttca tgacggatat cgatttatct gaagtcaata tccatgtagt agctgttgtt
    15601 cctgaaaaat tagaacaacc aacaatcgaa gaactttttg aagacgaaga ggaagagaat
    15661 gaataaagaa ttatcaagac acgagattcg ggaaatggca ttgcaggctt tatttccatt
    15721 agacttcaat gcagacctaa caaaagaaga tgcgattttc aacgcaatcg aattagacca
    15781 ccgcgacatg atcaacgaag atgaatcaga gtttgttcct gtttatcttg atacgctagt
    15841 tggcggtgtc tgtgcaaaaa aagatgaatt ggataaagtg attgaaaaac atttaaaaaa
    15901 caattggcac atcaatcgga tctcaaaaat ggatttggtg atcttgcgta tcgcgatttt
    15961 tgaaatgact tatgtgacag atgtaccagc ggctgttgct ttaaatgaag caatcgagtt
    16021 ggcaaaaaca tttagtgatg accgttcacg taaattcgtc aacggtgttt tatccaatgt
    16081 attgaaagaa ttagaagctg gggcgtaagt cctagctttt ttctatgaat catcataaac
    16141 ctgttataaa tcgggaaaat tctatggtag aatgaaaaca caaaaaatat ctgggagtgg
    16201 ttagatggca gaattgatta acggaaaaga attagctgaa aaaatgcagg cagagattgc
    16261 tgaaaaaatc caaaaattga aagataatgg tatccatccc ggattagtcg ttttattggt
    16321 aggggaaaat ccagccagcc aaatctatgt aagaaataaa gaacgtgtag caaaagaaat
    16381 cggaatccat tcattggtag agcgttatcc tgagacgatt tctgaagacg aactacttgc
    16441 agaaattgaa aaatacaatc aagatcctag ttttcatggt atattggtcc aattaccatt
    16501 gccaaagcat atagatgaag aaaagatcct gttagctatc cgccctgaaa aagacgtaga
    16561 cggttttcat ccgatgaatt taggcagact ccttgcgggt aaaccggaca agattccttg
    16621 tactccatac ggcatcatga aaatgtttga agcttattct atcgatccgg cgggtaaacg
    16681 agcagtagtt atcggacgaa gcaatatcgt cggtaaaccg atggctcagc tactcttgat
    16741 ggcagatgca actgttactg ttgctcattc taaaaccgaa aatctggctg aactggcaca
    16801 agaagcagat attttagtcg tagcaatagg acgtggacat tttgtcacaa aagaattcgt
    16861 aaaaccaggt gctgtagtga tagatgtagg gatgaatcgt gatgctaacg gtaagctgat
    16921 cggtgatgtg aaatttgatg aagtggagcc tattgcaggc tggatcactc ctgtgccaaa
    16981 gggtgtaggg ccaatgacta tcacgatgct gatgtatcaa accgtaaaat ctgccgaagc
    17041 ttttggagca ggtgaataga tggcacaaga atatttaact gtcactacat taacgaagta
    17101 tttgaaaaga aaatttgatg ccgatcctta tttagaacgc gtatatttaa caggcgaaat
    17161 atcgaatttc cgtttacgtg ccaatgccca tcaatatttc agcttaaaag atgaccatgc
    17221 aaaaatatct gctattatgt tcaaaggagc attccaaaaa ttacgattcc agccaaaaga
    17281 aggaatgaaa gtccttgtcg ttgggcgtat ttcattatat gaagcgggag gttcttatca
    17341 aatctatgta gagcacatgg agcctgatgg aataggtgct ttatatcaag aattggaaga
    17401 acgaaaagaa aagctgatga aggaaggcct ttttcaaggg cctaaaaaaa tgctgccacg
    17461 tttcccaaag cgaatcgcgg tccttaccag tccaagcgga gcggttatcc gcgatatcat
    17521 cacgacggtg aaaagaagat atccaattgt ccaattggtt ttgttcccaa cagttgtaca
    17581 aggaaaccaa gcagcggaca atgttgtcag gaatatccag agagtagaag agatgggcaa
    17641 tttcgataca atgatcatcg gtcgtggggg tggttcgatt gaggatttat ggccgtttaa
    17701 tgaagagcgg gttgctcggg cgatttatca agctaatacg ccggtgattt catctgtagg
    17761 acatgaaaca gataccacga tcgctgattt agtagcagat gttcgggctg ccactccaac
    17821 agcagctgca gaattagctg ttcctgtttt gtcagaagag ttgatgcgca ttcaagaacg
    17881 gcaagctaga ttgcagcagg cgtttgtacg ccagatccag cgcaaacaag aacggttcga
    17941 gcgtgctcga cgttcctatg tatttcggca gcctgaaaga ttgtatgaag gtcagaccat
    18001 caaattagac cagttgaaac agcgattata tcaagctaca cagcaaattt atcatgcgaa
    18061 agaaaaacaa acgatcgcat taagccacca attggaacaa gtggctccgc tttatcgagt
    18121 taaagcagct cgccaagaaa ctgcttatct agaaaaacgc ttagaagaga aaatccaaca
    18181 atatatgaaa caacagcagc agcgttttgc tcaagctgtt caatctcttg atttgttgag
    18241 tccattgaaa atcatgggaa gaggctacag ctatacgacg ttaaatgatc aagtagtaaa
    18301 aagtgtcacc gagattcatc aaggggattt gctgacgatc cattatcaag atggaatcgt
    18361 taaaggacaa gtacaagaga tagacaaagg agaataaaaa tatggaaaat ccaacttttg
    18421 aagagtcact gcaagaatta gaaaaaattg tcatgcagtt agaacaagga gacgttccat
    18481 tagaatcagc tctagattcg tttaaacgag gaatggaatt aagcaaacat tgccaagata
    18541 cattagctaa agcagaagag accttgacga aaatgatgac agaatcaaat gaagaagttg
    18601 attttgacgg aaacgaggaa agctgagatg agattaactg acttttcagc tattcatcta
    18661 cctgctgtag aaaaagaaat cttgtctttt ttagatgagc atacaacgga tagaggactc
    18721 tatgatgcga tgagttattc agtgaaagca ggcgggaaaa gaatacgtcc cttattactt
    18781 ttaacggccg ttgcttcctt tgatgagcct attgatgttc ccgtctatca agtagcagct
    18841 gctttagaaa tggtgcatac gtattccttg atccacgatg atttgcctgc gatggacaat
    18901 gatgatcttc gtagaggaaa acctaccaat cataaagtat tcggcgaagc attagctata
    18961 ttggccggag atggtttgct tacaggagca ttccagctaa tcagtatggc acacttaggt
    19021 aattctccta agcttctgct gcttcagcaa ttagctgttt gtgcgggatc acaaggtatg
    19081 gttgctgggc aagctgcaga tatcgagggc gaatcgaaaa agctttcttt agaagaatta
    19141 gcatttattc atgaaagaaa gacagggcat ttgattcgtt atgccttgct ggctggtggc
    19201 atattagcga agcaacctga agaaatctta ttgctacttc aacgattagc cgaacattta
    19261 ggtttagctt ttcagataag agatgatcta ctcgatgtga ttggtacaac gaaaacatta
    19321 gggaaaacag ctggtaaaga tgaacgtatg gaaaaaaata cttacccgcg tttattaggc
    19381 ctagaaaaga cacgtgaggc gttggagatt gagctgttat ccgccaacaa gatcatagac
    19441 aaattagaag aggacgtttt ttcttttgat ggcgggctga tgcgccagat gatcaagcaa
    19501 tttgatgtgg agaaatgagg gaaagaatgg aaaaagaacg cgtagatgta ttagcggtca
    19561 aacaaggatt atttgaaaca agagaacaag ccaaacgttc agtgatggct ggtttgattt
    19621 acaacgaaaa aaacgagcgg tttgataaac cgggagaaaa aattccagtg agtagtgaat
    19681 taagagtcaa aggtaaaaaa cttccttatg tttctcgagg gggattaaaa ttagaaaaag
    19741 cactcaaagc atttgatcta tctgttgaag gaaaaacatt gttagatatt ggtgcatcca
    19801 ctggcggatt tactgatgca gctttgcaaa atggcgcaaa aatgagttat gctttagacg
    19861 ttggctacaa tcagctagct tggaaaataa gacaagatcc tagagtcgtc gtaatggaaa
    19921 gagtgaattt tcgttatgca aaacccgaag actttacctt aggaattcca gaagttgctg
    19981 ttatcgatgt ttcttttatt tcactaaaac tgatgctgcc tccattacat gctattttaa
    20041 aagaagaggg agaagtgatt gctttaatca aaccccaatt cgaagcaggc agagaagctg
    20101 tagggaaaaa cggaattgtt cgtgaccctc agacccatca aaaagtttta gaagacattt
    20161 tgtcatttgc ggcacaaggt ggatatgatg tgctggaatt aagttattct ccgatcacgg
    20221 ggggagaagg aaatatcgag ttcttggctc acttgaggaa agtacccgaa agcggaacaa
    20281 tcaattcagc tattaatatg gcagaagtgg tttcaaatgc acacgaacag tttgaccata
    20341 aataaattgt aactgtgaaa atcaagtgag aagtatgcgg attcttcttt attataccaa
    20401 ggaaataagc tatcattgat taagaagaat atgctaagga gcgaagacgt aatgagaaaa
    20461 aaagatcggc atcgtttgat tactcgattg ttgagtgagc aagatatccg aaagcaggaa
    20521 gaatttgttg aaatcctgaa aagcaaagga atatctgtta ctcaagctac gatttccaga
    20581 gatataaagg aactgaaact gatcaaggta ccggcttcag atggcggcta ccgttatagc
    20641 ataccagctg aaacaaacga agatgtaaat actaaattgg aaaaactatt aaaagacgct
    20701 ttcgtggcag ttgaccaaat ggaaaaattt gttattttga aaacattgcc gggaaatgct
    20761 tcggcagcag caaatttgat tgataaacgt tacaagaaag aattattttc gattatcaat
    20821 gatgacgata atgttttgat gattacacga actgaagacc aggcagtttt attgaagaaa
    20881 gacttcctgc attaccttta agttgaggag cgaatgtgat gctacaagaa atcagtatta
    20941 ctaactttgc gattattccg gaattgcggc tttcttttca cgaaggaatg accgcgctga
    21001 ccggagagac tggtgcgggt aaatccatta ttatcgatgc tttaggtctg ttagcaggag
    21061 gaagaggttc aagcgattat atacgtcaag gagcagaaaa atgtgtgctt gaagggttgt
    21121 ttgaactacc aaaacaagaa ggattctctg aactgatggt tgaattaggg atcgaaacag
    21181 atgaggacaa tctgattgtt cgacgggata tgtccttaac tggaaaaaat gtttgtcgag
    21241 tgaatggtca tattatcaca ttagctaatc tgagaagaat cggcagttat ttagtagata
    21301 tccaaggaca aaacgaacat caggaactgc tccagcctga atcacatctt gctttattgg
    21361 atcgttttgg agatgtagct ttccaacaga agaaaaagag ttatcagcaa gaatatatct
    21421 cttatcgtga gctggaaaaa agggtacgaa aagtgcagca aaatgaaaaa tcctatgttc
    21481 agagaataga tatgctccat ttccagcaag aagaaatagc tgctgctgat ttgcaagtcg
    21541 gagaagaaga gaaattaaaa gaagaaagag aaaaacttag caattatcaa aaaattgctg
    21601 atggattagc tgcaggttac ggagcactga cgaataatga acaaaacagt gtagatggtg
    21661 ttggcttggc cgtttcagaa ctgcaaggga tcgcccatct agatgtggag tatgaagcaa
    21721 tttatgaaaa tatccaaagt gcttactatt tgctgcaaga tgcaatcggc gatatgagtc
    21781 gtcagattga tttattggag ttagatgaga gtcgtttaga agaagttacg caacgtttag
    21841 aattaatccg acagttgaaa cgtaaatacg gcgaatccat tgagtcaata ttggcttact
    21901 atgacgaaat caccgaagag ctagcttctt ctgatttttc agaaggtcaa ttggacaaaa
    21961 tgaaagagga actagagcaa aaagagcttc tacttcagca acaagccgca gatcttcatg
    22021 aagcgcgtaa aaaaatcgca aaagaattgg aaaaatccat tctgcatgaa ttgaaaagtc
    22081 tgtatatgga aaacactgag tttgaggtac gtttcttaaa agaagaaaat agacaattga
    22141 atcatgatgg atttgaccaa atcgaatttt acattacgac caatccagga gagccactga
    22201 agcctttggt gaaagtcgct tctggtggcg aactgtctcg gatgttgctt gctttgaaaa
    22261 ctattttttc ttctgagcaa ggtgtgacaa gtattatttt tgatgaagtg gatacaggtg
    22321 tgagcggaag agttgcacag gccatcgcag ataaaatttc tcaaatatcg aaatactctc
    22381 aagttttgtg catcactcat ctgcctcaag ttgctgcagt cgccgactat caatattata
    22441 ttgtgaaagc agtgattgat ggacgtacgc aaacttctgt ttcagagttg aaaacaaaag
    22501 aaagagaaga agaaattgca cgtatgctgg ctggaagtga gattacaaaa ctcacactcg
    22561 aacatgcaaa agaactattg aaactcgcaa aaaggacctg agccacctcg cagtggttca
    22621 ggtccttttc agcagctgat agctatattt tatttttaca tgacactcat tacagcagtc
    22681 aatacaacag atccaatcgt taaaatcagc attgtccaaa tgacaaattt tgttacttta
    22741 gcaaaagtac ttgtttgttt tttttcacgc attgttttca acctcgtcat taattagttg
    22801 attcaagtgt acaatctttt ttccatttcc acaagagggc ttttttataa aaacttccct
    22861 ttttttaaat aataggtagt tacgatacaa ataaataatg ttaatagaac tagccatata
    22921 aaggcatcat ccctttcagc aataggtaac ttaatgttca ttccatagat actgccgacg
    22981 attgtcggta tagttaaaat aatcgttaaa gaagttaaaa ttttcataat attattcaga
    23041 ttattcgata cgattgctga aaaagtctga ttcatttgtt ctactagttt taattgaatg
    23101 cgagaagtag tcattgcctg ctctgtttcc accaatacat cacgtaaatg atttttcaaa
    23161 gcatgatttt cttggaaaag tttattttgc gctagttctt tcaatgcatc taaattagca
    23221 gaagtcgctt ctctgaaata aacgaggctt ttttggatat ccatgatttg ataaagttgt
    23281 ttgttttcag tggatacttg aagtttggct tccaaagtat cgcattgaga ttgaagcgta
    23341 gctaaataac tgttgtaaga gagtgtgacc tgccaaatga attgaaagaa gatattgaga
    23401 ttaggcgaaa tatcactttt tggaaaggtc tggctaaaga ctttctttaa aaacagtggt
    23461 tcatgattcg taattgtgat aagcttcttt ttgggcgtca aaataataga gagcgggtat
    23521 gtatccactt gaaaataacc gctaggactt gttttagcaa aaggatattg taacaataat
    23581 aacgctggct ttgtcaactt tgattgattg aattcttctg tacgggaatt ttctgcatcg
    23641 tccaatatgg aagtgatgta atctgacgga atttcaaatt gatgtgtcag ctgatgaatc
    23701 tcttcttgat taggacgttc tacacaatac cagatcgttt ggtcagtttc ctttccggta
    23761 ttacgcagtt tctcattatc taatgtaaaa tatttgatca tgattttcct cctgttgcct
    23821 gtttctttta ttataacgga tagggaattg gaatacatgg aatgtgtttg taagatatag
    23881 aatataactg cataaattta aataaaatga aacagttgtg taaagtatat acagtatact
    23941 tgaagcaacg ataaaaaagg agtttacgtt catgggcaca ttcacaccac ttatcttgtt
    24001 ttggtatatt tacccggtaa tcgttttgtt tggttgccaa tttcttgtaa aattattttc
    24061 gttaaatcgt cgttttaaaa taaaagcccc tgatttggcg attccttttt tgtggggcgg
    24121 tatgcatgca ttgtctagaa atacagggac aatttctatc ttaccgtttt tctttatttc
    24181 tgttttgcta atgggaattt gtattgctgt tttccaagca tattattatg aagaaattat
    24241 ttatccgcgt tatttcaaga tgacttggcg tttggttttt ctgttgacaa tcgtcttgta
    24301 cgctgtcttg atcattgtga acatactttc ttacctatga aaaaaataga aaagctgtaa
    24361 aaagtctttt aaaaggcttt ttgcagcttg atttttaaaa aaatgtttat gaataaaaaa
    24421 agttgttccc ggatttccca gaaaaggtgg tagaaagtgg gggattgtgg tagactaatt
    24481 ttagttagtg gaggaatggg gggctttcaa tgttgatggg tgaattccaa cataatattg
    24541 atgcaaaagg acgtttaatc gtgccctcaa aacttcgtga agaacttggc gaaaagtttg
    24601 ttctgacacg cggattggat ggctgtcttt tcggctatcc gatgagcgaa tgggaaaatc
    24661 tggaagctaa actgaacgaa atgccgttgg ctaaaaaaga cgcacgtact tttgtgcgat
    24721 tcttctattc ggctgccact gaatgcgaac ttgataaaca aggacgaatc aatataccca
    24781 gcacgttaag aaattatgca gctttgacaa aaggttgcgt agtcatcggt gtatctaacc
    24841 gaattgaaat ttgggatgag acacgatggc aagatttttc tgcagcagca gaagagaact
    24901 ttgacgaaat tgctgaaagt atgattgatt tcggactata agaataggaa gaggctgact
    24961 aatgactgaa acatttcaac actatacagt catgttgaaa gaaacggtag atggattgaa
    25021 catcaaaccg gatggcgttt atgtagactg tacactcggc ggtgccggac atagtgaata
    25081 tttattaagc caactaagtt ctaaagggca tctgtatgcg tttgaccaag atcaaaaagc
    25141 aatcgatcac gccaagctgc gtttagcttc ttatgtcgaa caaggtatgg tcacatttat
    25201 caaagcgaac ttcagagaat tagaagaacg cttgagtgag catgtagata aggtagacgg
    25261 cattttgtat gatctagggg tttcctctcc tcagctagat gaagcagaac gtggatttag
    25321 ttatcatcaa gatgcaccgt tggatatgcg catggatcag tcagctcctt tatccgctta
    25381 tcacgtaatt aatgaatatt cctaccatga attagtaaag attttcttcc gctatggcga
    25441 ggagaaattt tccaaacaaa ttgctcgtga aatcgaacga gtacgaaaaa caaaaccaat
    25501 ccaaacaact ggtgagcttg tcgaaatcat taaacaagtc atcccagctc ccgcaagaag
    25561 aaaaggcggg catcctgcaa aaagaatttt tcaagctgtg cggattgcag taaatgacga
    25621 actcggtgcc gaagaggcct ctttagaaca ggcaatccgg ttattgaaag tcaatggaag
    25681 aatcagcgta atcacattcc attcattgga agacagaatt gtcaaaagta tgtttaaaga
    25741 atatagtacg gtacaagatc taccaccggg acttcctgtc atacctgacg aattccaacc
    25801 agaactgaaa gtcattactc gtaaaccaat ccttccttca gaggaagagc taacagaaaa
    25861 caatcgatca cgcagtgcaa agttacgtat tgcagaaaaa ataagaatga aagaggagta
    25921 gaatgatggc agaattaaag aaaatgcaag attacgaata tgatttacct gaattggtgg
    25981 atcagccgga acaacaaatg cctgattctt cttcgaatca agaaatcatt cttccacaat
    26041 caccggcaaa acgattaaag cagatttctg ctttggaaaa aattgctgtg gcaagcgtgg
    26101 cgattgctat tgttgcttta tgtgttttaa cagttatgct gcgcacaaat atcagcggag
    26161 ctgaaaaaga aatcacgtca atacaaacag aaatcaatga taaaaagcaa gaaaaaacga
    26221 gtttagaaca agaaaaaaac gaactttctc gtactgaacg gattaaacaa atcgcagaag
    26281 aaaaaggatt gtctattaat gacgacaatt taaggaaagt gaagtaaatg agtcttaaaa
    26341 ataaaattcg gcggtttatg gaaaagaaaa atctaaatcc gatgaacaat cgcaaaaaag
    26401 taggtatcat tttatttgct acgagtattg gattgttctt tttatttgcc gtccgtttct
    26461 cgtatatcgt tattggaggt catgttgctg gtacctcatt agctgaaaaa acaaaacagt
    26521 tgtaccaagg aagtgaagta gtaaaagcaa aaagaggaac gatttatgat cgtaacggtg
    26581 tggcgctcgc agaagatgcc tcctcttatt caattaaagc gatactctca aaaacatata
    26641 cctctgggga taaaaaactg tatgttgaag aaaagaattt tgataaaata gcagaaatcc
    26701 tgcataagaa tctttctata gacaaaaaag atgcactgaa tattttagag gacggcgcaa
    26761 aaaaagagct gtatcaagtt gaatttggta gctatgggaa aaatatctcc caagaaacca
    26821 agcaaaacat cgaagcggac atgaaaaaag aaggtgtcgc tggtctttat tttgtcgacc
    26881 atcaggctcg gatgtatcca aatggcgtct tttcttctca ttttattgga tacgcagttc
    26941 cagacaaaga tgagaatggc ttagttggta aactaggttt ggagtctgct tacaatgata
    27001 tcttgagcgg taaagatggt aagattattt atcaaaaaga taattttcaa aatcctctgc
    27061 caggtacagt ggcagaagaa gaaaaagctg tcgacggaca agatatctac acgactttag
    27121 acagcagact acaaagttat ttagaaacac tgatggatca agtaaatgaa gaatatcagc
    27181 cagaagaatt gacagcagtc ctgatgaaag caaaaaccgg agaaatcttg gcaatgggac
    27241 aacgacctac tttcaatcct gaaacaatgg aaggattgac tggaaaagat gctatctggc
    27301 gtaatttctt ggtacaagat agttatgaac caggatcaac catgaaagtt ttcactactg
    27361 cagctgctat cgaagaagga gaattcaacg agaatgaaac cttccaatct ggaaaaatcc
    27421 aagtagaaga tgctacgatc aatgaccatg actttggtga aaaaggtgtg ctgaccatgc
    27481 gtcaagctct ttcatggtca agtaacgtcg ggatggtcat actggaacag cgattaggcg
    27541 gacgatggta taactattta caaaaactgg gatttggaca aagtactcat tctggattag
    27601 atgatgaagt aaacggtgct ttacctacat taaatattgt cgaccgagca atgagtgctt
    27661 atggacaagc ggtaggtgtg acgaatttcc aaatgatgaa agctttcact tctattgcga
    27721 ataacggtac aatgattcaa cctcgatata tcagcaaagt ggtggatccc caaactggag
    27781 aagagcgaac aactcaaaca gaagttctag ggcaaccttt ttcaaaagaa acaacagaaa
    27841 aagtccgtga atatatgaga gatgttgtcg aaagcgaaaa ctacggtagt gcttatggtg
    27901 tatatagtgt acctggatac aatgtatcgg caaaaaacgg aacagcccaa atcgcttctg
    27961 atacaggggg atatcaaaca ggagatacag cctacctgta ttcgattgtg gagatggttc
    28021 cttctgaaga tccagactat gtcttgtatc taacaatgaa acaccctaag acatatgatc
    28081 gaatggcatt ggctaaaatc gcaaatccat tgatgaaacg ggcaatggat tttaaagaaa
    28141 ctgaagaaga ttcagataca gaaacaaaaa cagaaaaagt atccgtagcc gattatcgta
    28201 atcttgaagc ggacgttgca gcagctgatg ctcaaaaaag tggactgcaa cctgtagtga
    28261 tcggtaatgg taaaaaagta caaaaacaat ctactgccaa cggtgatcag ttgatctctg
    28321 gagaaaaact gatcctatat actggtggtg ataagctgat gcctgacgta acaggatggt
    28381 caaaagcaga tatcatgaag ctggggaaaa tcctcggtat tgaagttagt tttgatggag
    28441 atggttattg tgtcaaacaa gaacttgctc catatgaaaa aatcactgaa gacaaactta
    28501 gttttacttt agaagaataa gaagagaaat aggagagaaa agagcatgga atggacacaa
    28561 gcattgattc ccattgtcag cagttgtgca atgacaattg ccgcaatgcc gctatttatt
    28621 ggttattttc aaatgaaaaa gcaaggtcag gcgattcgtg aggagggacc aaagtggcac
    28681 aatagcaaag ccggaactcc tacaatgggc ggcttagtgt ttctgatcgg ctctattttg
    28741 acaggaattt gggttggagc ttggcaaaaa cagctaactc ctactctttt catcttgctt
    28801 tttgtattag cgttatacgg agtaatcggc tttcttgatg attttataaa aatattcaag
    28861 aaaagaaaca tgggactgaa ctcgaagcag aaattgattg gacagattct agggggaatc
    28921 atcttttatc ttgtttaccg ttctgaaggt tatccaggtg tattgaattt cttcggacta
    28981 gatctacctt taggaatcat ttatggtatt ttcgctctct tctggcttgt tggattttca
    29041 aatgcagtaa atctgacaga tggcatcgat ggattagttg ctggcttagg aagtatctct
    29101 tttgcagctt acggtctaat tgcttggcat cagcatcagt atgatgtatt aatcatttgc
    29161 ttaagtgttt taggaggttt actgggtttc ttcgtctaca acagaaaacc tgccaagatt
    29221 tttatgggag atgtcggttc attagcgttg ggcggacttt tagcggcaat ttctataatg
    29281 ctaaaccaag aatggacatt gcttttgatt ggtttgatct atgttatgga aacagcaagt
    29341 gtgatgcttc aagttacttc ctttaagctt acaggaaaac gaatttttaa aatgtctcca
    29401 attcatcatc actttgaaat gtgcggatgg tcggagtgga agattgatac agttttttgg
    29461 ttgatcagca ttgtgacttc gttgatcaca ttatggatcg tttggtagga gatgacggga
    29521 aatgaaaaaa atatcaacat atgaaaataa gaaagtgctt gtcttaggac tcgcaaaaag
    29581 cggagtaagt gcggccaaat tattacatga attgggcgca cttgtcaccg ttaatgatgg
    29641 aaaacctttt gacgaaaatc cggaagcaca agagctgctt tctttaggga taaaagtaat
    29701 aacaggtagt catccaatcg aattgttgga tgaagaattt tcattgatgg tcaaaaatcc
    29761 agggattccc tacagtcatc ctttagtagc aaaagcccaa gaaatgggta ttccggtaat
    29821 tacggaagtt gagctagctt acgaagtagc ggaatgccca attattggga ttacaggaac
    29881 gaacggaaaa acaacgacaa caacgatgac aggactacta ctgaatgcag gagcagatca
    29941 aggaattgca cgtttagcgg gtaatattgg gtatccagca agtggtgtag cgcaagaagc
    30001 aaaatcagaa gataaaattg tgatggaatt gtctagcttc caactcatgg gaatcacaga
    30061 tttccgccct catatagcgg tgattaccaa tatctatgaa gcacatattg attatcatgg
    30121 tacaagaaaa gaatatgtca aagctaaatg gaaccttcaa aaaaacatga cagaaaaaga
    30181 ttatctgatc cttaactgga atcagtcaga actacaagaa ttagcgcaaa gaacaaaagc
    30241 acgcgtactg cctttctcga caaaagaagt gttggaagac ggtgtgtatg ctgacgatta
    30301 ctcaatatac tataaaaaag aaaaaataat ggaaatatct gaacttggcg taccaggtaa
    30361 gcataatgta gaaaatgcac tagctgctat ttctgtagca aaattgtatg gtatatcaaa
    30421 tgaagctata cgagaaacgt tgcatttttt ccatggcgta ccacatcgta cgcaatatgt
    30481 aggagaaatc caaggcagaa aattttataa tgattcaaaa gcaaccaata ttttagcgac
    30541 taaaatggct ctaagtggat ttgaaacgtc taaggtcgtg ttattggctg gcggattaga
    30601 cagaggaaat acatttgatg aattaattcc ttcattaaaa ggaatcaaag caatggtcgt
    30661 atttggccaa acaaaagaaa agttgatgga tgctggaaaa aaagcaggca tcgagacaat
    30721 agtaacagcc gattctgtag aacaagcagt tcctttagca ttagaaaaca gtacagatgg
    30781 tgatgtagtt ttattatcac cagcgaatgc cagctgggat caatacccaa attttgaaac
    30841 tagaggaaac agattcatgg aagctgtgaa ccgattaaaa tagaaaaagt agaagcgagc
    30901 gataaaaaat gaaaattttg gttacaggcg gaggaacagg gggacatatt tatccagctc
    30961 ttgcctttgt caattatgta aagactcaag aaccgaatgc tgaattcatg tatgtgggag
    31021 caaaacgagg tctagaaaac aaaatcgtcc ctgatacagg aatgcctttc cataccttgg
    31081 agattcaagg atttaaacga aaaatttcca tgcataacat caagacggtc cgattgtttc
    31141 ttaagagtat ccgtcaagca aaaaaaatcc tcagtgattt tcaaccagat atcgttatcg
    31201 gtactggagg atatgtttcc ggagcggtag tgtacgctgc agccaaaatg ggtattccaa
    31261 cagttatcca tgaacaaaac agtgtaccag gtgttaccaa taaattttta agccgatatg
    31321 tggatcggat cgctctttca tttaaagatg cggcttcctt ttttcctgaa aacaaagcag
    31381 ttcttgtagg taatcctcga gcacaagaag tagcagatac taaaaaatca gatattttga
    31441 aaacatttga tttggatcca gaaaagaaaa cagtcttgat ttttggcggt agtcaaggag
    31501 cacttaaaat caatcaagca gtatcagttt ttttaagtga atatattcct tcttcttacc
    31561 aagttttgta tgcttcagga gatagatatt atgaagagat cctaaataaa ataaatcctg
    31621 aaatacaaaa tattagtgtc cagccttata tcaaaaatat ggcagaggtc atggcttcca
    31681 gtgatctgct ggtggggcgt gctggtgcaa cttcgatcgc agaattcaca gctctggggt
    31741 taccggcagt gttggttccc agcccatatg ttacgaatga tcatcagact aaaaatgcaa
    31801 tgagtcttgt tcacgcagga gcagcaaaaa tgattgcaga taatgaacta acaggtgaat
    31861 cactaagtca gacagtcaac gaaatcatgg gtgatgaaga attgcaaaag caaatgtgcc
    31921 gagcttctaa agaacaagga atccctgatg cttcaaaacg tctttatgac ttagtaaaac
    31981 aaataatcaa aaaataaagg cggtggtctt agtgagtaag aaaaaagaac caaaaaaatt
    32041 gtctcatccg tcttctgatg aaaacaattt gactccttgg caaaaggcta accgaaaata
    32101 tctggcagaa caagagatga aaaaccaaga gccaaaaaaa gaagacataa cattagatac
    32161 acccctttca gattctgaag aagaaaaaac ggttcaagag gaacagcaag aagaaagcca
    32221 gtccgagaaa aaaatcgaat tttttgaaga gatcaagcaa aagaaaaacg gtggaccata
    32281 taacggttct tttttgaacc ggctgcccaa tttaaaaagt caacggcaca aagtactatt
    32341 tcgtcggtta gctttgatca tcactgtatt gggtataccg ctgatttttt tgatctatta
    32401 tgtttctcct tatagcaaat tacaagcagt tgcagtatca ggcaataaga cagtcaacag
    32461 ccaagaaatc atctctgata caaaattgtc attaggagaa aatgtttggg gacagtattt
    32521 tcatcgatct acttatatcg atcgccttaa aaaagcacag ccaagaatcg aaacagcaaa
    32581 tatacatttc aaagggatga atgaattcga tttggatgta acagaatata aagagattgc
    32641 tttgatcgca aaaaacaatc aatactaccc agtgattgaa aatggaacag tattagatga
    32701 aaaagtagca aatcctacaa aaaatctccc tatcttggaa gagttcaaag actctgcaaa
    32761 aatcaaagaa ttaacaaagc aatacaatca gttatcatca gaattacaaa aagcaatttc
    32821 tgaaatcaag tacacgccaa gagcaagcaa taaaaatctg atccaattga atatgaatga
    32881 cggcaatcaa gttattgtaa atatcaataa tcttgcgaac caaatgaaat attattcgca
    32941 agtagccaaa gatatggatg aaaaaggtgt gatcgacatg gaagttggta tcttctcgca
    33001 tccttacggt agcactcaag aaacggaaga atcgggccaa tcggaagaaa caactgaaag
    33061 tgaagaaaat gcggatcaaa caaacgaatc aagtgaagag gcagaaacgc aaaaagcaca
    33121 aacacctgga tcgtctagca caaacggatc atctgattca aatgattcaa gtgaaacaag
    33181 tcaaatagaa gataatccaa gtacaactcc gtcaagttta aatgaaaatt gataaaacaa
    33241 ctttaaaaag taagaatgta ctttctaaaa accagtaatt tatggtagaa ttggaagcag
    33301 tgaatatatc tattaataag tatattttaa aacggacgct agttgttcgc ttgtatatgg
    33361 aatagtaagt aggagggaat cccattcatg gcaaaaacag gaatgtatgt aggccttgat
    33421 attggaacga catctgttaa agttgtcgtg gctgaatata tcgacagcca aatgaatatt
    33481 attggagtag gaaacgcaaa atcagaaggg attaaccgag gcattatcgt tgatatcgat
    33541 aaaacggtcc aagcgataca acgagcagta cgacaagcag aagaaaaagc aggtatccag
    33601 atcaaaggcg taagtgtcgg tttgccagca aacatgcttg aagtagaaaa ttgccaggga
    33661 atgattgcag ttaacggaga ttcaaaggaa atcaccgatg aagatgtcag aaatgtggct
    33721 tcagctgccc ttgttcgttc aatacctcct gaacgtcaaa tcgtgtcaat attgccacaa
    33781 gattttactg tcgatgggtt cgagggaatc aaagatcctc gtggaatgat cggcgtaaga
    33841 ttagaaatgt acggtctgtt gtttacagga cctaaaacga tcatccataa catacgtaaa
    33901 tgcgtggaaa atgccggatt aatcgtcaac gaaatggtga ttactccttt agcgctgact
    33961 gaatcaattc tttctgacgg agaaaaagat tttggtacga tcgtcattga tatgggtggc
    34021 ggccaaacaa caacggctgt tatgcatgat aagcaattga agtttaccaa tcttgaccaa
    34081 gaaggtggcg aatttgtcac taaagatatc tctattgtat taaatacgtc atttaacaat
    34141 gcagaagcgt tgaaaataaa ctacggggat gcatacccag aacggacatc accagatgaa
    34201 gaatttccag tagatgtgat tggtcagtca gaaccagtga aagtcgatga acgctacttg
    34261 tcagaaatta tttcagctcg aatggaacag attttcaaca aagcaaaaga tgcattggac
    34321 caaatcgaag cattagagtt gccaggtggc gtcgtattga caggcggagc tgctagtctt
    34381 cctggtgttg tggacttggc acaagaaatc ttcggcgtaa atgtaaaatt gtatgttcca
    34441 aatcacatgg ggctgagaaa cccggtattt acaaatgtaa taagtatcgt ggattattca
    34501 gcaaacttga gtgaagtgta tcaattggca aaaattgctg ttacgggtga aacctcagca
    34561 gctcgtcaaa tggtagttga acaagaaaca acaaacacat atgagagcta tgaagcacct
    34621 gaagaaacaa tctacgatga gccggaacca aaagagtccg gagaaaatgt aaaaaataaa
    34681 atcaagggtt tctttacaaa tatttttgat taattcatcc tgggaggaat aagatatgga
    34741 attctcaatt gataataata tcaatgacgg cgcagtaatc aaagtcatcg gagtcggtgg
    34801 tggcggtgga aatgctgtaa accgaatgat tgaagaaaac gttaaaggtg ttgaattcat
    34861 tacagccaac acagacgtgc aagcattaaa aaattcaaaa gctgaaacag ttatccaatt
    34921 aggccccaaa tatactcgtg gtttaggtgc tggttctcag ccagaagttg gacaaaaagc
    34981 ggcagaagaa agtgaacaat ccttacgcga agctttagac ggtgcagata tgattttcat
    35041 cactgcagga atgggtggag gaaccggtac aggtgctgca ccaatcgttg caggtatcgc
    35101 gaaagaattg ggcgcattga ctgttggtgt cgtgacacgt ccattcactt ttgaaggacc
    35161 gaaacgtggc cgttttgctg cagaaggtat cgctcgtttg aaagaaaatg tggatacatt
    35221 attaattatc tcaaataacc gtttattaga agttgtagat aaaaagacac cgatgcttga
    35281 agctttccgt gaagcagata atgttttacg acaaggtgta caaggtatct ctgatttgat
    35341 cacagcgcca ggttacgtta accttgactt tgctgacgtg aaaacagtga tggaaaacca
    35401 aggtacagca ttgatgggga tcggtgtggc tagtggagaa gatcgcgtag tagaagcaac
    35461 gaaaaaagca atctcctctc cattgcttga aacatctatt gatggagctg aacaagtact
    35521 tcttaacatc acaggcggtt tggatatgac attgttcgaa gcacaagatg cttcagatat
    35581 cgtagcaaat gcagcaactg gcgatgtaaa tatcattcta ggtacatcta tcaatgaaga
    35641 aatgggcgat gaaatccgtg tgacggtcat cgcaacaggt atcgatgaat caaaaaagga
    35701 acgcaagtct agccgaccag ctagacaagc acaaatgcaa tcacctgctc aaaagactgt
    35761 attagatatg gatcaagcta aaccaacttc ttcagaagaa gaaaacagtt ttggcgattg
    35821 ggatatcaga cgtgaacaaa atgttcgtcc tagagttgat gattccaatt ttgacaatat
    35881 cgaaaaaaaa gaatttgata cattcaaccg cgaagaaaca aaatctcatg gcgatgatga
    35941 attaaatacg ccaccgtttt tccgtcgtaa aaaataaagg agaggaagag cacatgattg
    36001 ctgacaactt gcagaaaatc aagcaagaaa ttcaggattc gtgtgctctt gttcatcgtg
    36061 atccgaaaga agttacatta gtagctgtaa caaaatctgt tgaatccgct caagctgaag
    36121 aattggttag agctggcgtt atgaattgtg cagaaaaccg agtagataaa ttattagaaa
    36181 agaaacaaga tttatttgat tttcctgaaa taaagtggca tttaattggt aatttacagc
    36241 gcagaaaggt aaaattgatt gtaaatgaaa ttgattactt tcatgcgttg gacagtttaa
    36301 gattagcaga agaaatccag aagcggttag agaaagaatt atcctgtttt attgaagtaa
    36361 atgtttctgg tgaggaatca aaacatggaa tttcaccaga tgagctttta ccgtttgtgg
    36421 aatctttagc tgcctgcaca aaaatcaagg ttgttgggtt gatgactatg gcgcctaaag
    36481 aagcttctga tgagcaaatc cataaagtgt ttggtacgct gaaagaattg cgtgatcttg
    36541 ttcaagcaaa aggttatgcc catgcaccat gtagtgaatt aagtatgggg atgagtcaag
    36601 actttcaaat tgcgattgaa gaaggtgcaa catttatccg tgtaggaaca gcgctattca
    36661 aagacgaata aaggaggaac aaaaatgccg cttttaaaca gaggagcaat tgctaatttt
    36721 ttcggattag ctgatgagga agagtacgaa taccaagatt atcctgaaac aacaaaaaag
    36781 gctgtacagc caactaaaaa aaatacaaca cagaatcaat caactcattc tgtatctgct
    36841 gcgaatactc atgaaaaaca aaaaacggcg acttcacgtc ctgtaacgca tgaaagtatt
    36901 cagccggctg aaaagaaaaa agtaattgaa ctacatcaat cacctacaaa aactgtagcg
    36961 aaagaaagaa cagcttcaag aacctctaca caacctaaag caaatcttgc tggaaaaatc
    37021 actgtaatgg aaccaagagc ttattctgaa gctatggcga ttgctaaacg aatcattgct
    37081 ggagaagcaa ccttagtgaa ttttcattta gtagaagaaa aacaagcgag aagaatcgtt
    37141 gattttctaa caggaacagt ttatgcacta gatggagata tcaaacgtgt tggagatgag
    37201 atttttcttt gtacaccgac tgggatggag attgacagtt caaccgctca atcttttgca
    37261 gatgcgaatt tgtttgatct gtaagaggag gaactacgat ttatactatt gcactattac
    37321 ttcatttact tcaacgggca gcctatttct atagcattat cttgatggta tatgcattgc
    37381 tctcttggtt tccaggcggg tatcaatcag ggctaggacg attattagct aagatctgcg
    37441 aaccgtatat cagtttgttc gatcgtctgc ctttgaggat tggacccttg gatttcacaa
    37501 ttttaggggc aatcctgatc ttgaacttag ccgtacaagg tttagcacag atcgttatat
    37561 ggataactgt ccatttagtt tattgattga agcaacaaaa tctttattct cagaatagat
    37621 aggaggggaa aattttggat gcaaatgtat accagcactt tcgggcagat gaacgtacat
    37681 ttatcgattc ggtaggcgat tggattgaac aggttcaagg acaatatgca ccctatctga
    37741 ccgaatttct tgacccaaga caatcctata ttttagaaac actgattcga caaagcagtg
    37801 atttgcgttt catgttttat ggcggatatg aacaggcaga aagaaaaaga tgtttgattt
    37861 tccccgatta ttacgaacct gtagaggaag attttgaaac agcattgtat gaaatccatt
    37921 atcctagcaa atttgccagc ctaagtcatg ggaaaatcct tggaacttta gtgggaacgg
    37981 ggatcaaacg ctcttacttt ggcgatatca tctcggacgg tgatcgctgg caagtattta
    38041 ttgcaaatga ggtggatcat tttgttgctg cacaagtaac aaagattgga aaggttgctg
    38101 tacgcttgga accaatcaaa tacacagaaa tgattatgcc gaaagatagc tggacacaag
    38161 aaagaggaac agttagttcc atgcgactag acagtgtgat ctctgagatt tataatattt
    38221 ccagacagcg gtccaagcag ctgatcgaag ctggtaaagt aaaagtgaac tggacagaaa
    38281 atacaagacc tgattttgta cttgaactat tagatattat ttcagtcaga ggttatggca
    38341 gagtccagat ccaagaactt gaggggaaga cgaaaaaaga aaagtacagg gtactgttcg
    38401 gtgtattacg taaataaaat aaaaaggtgg tttactcatg gctttaactc cattagatat
    38461 ccaaaataag acattcccga caaaaatgcg gggatataat caagacgaag tagatgattt
    38521 cttagattta gttgttcgtg actatgagga attgactcaa agaaatcgag aattagaaaa
    38581 agcagtcaaa cattctgaag aaaaacttga gtacttcaat gaattaaaag atgctttgaa
    38641 ccaatcaatc atcgtagctc aagatacggc tgataaagta aaaacaagtg caagcaagga
    38701 atccgaagtg atcgttactt ctgcacaaaa caaagcagat gagttagttg cgaacgctga
    38761 aaaacgtgca catcaattaa caactgatgc agaagaaaaa gcaagaaaaa tcttgacaga
    38821 tgcaacagaa aaagcaagac agcttgcgac agaaactgaa gatcttaaga aaaaaacacg
    38881 agtattccat caacgtatca gcttgatgct tgagtctcaa ttagaacaag tgaaaagtcc
    38941 ggaatgggat gaaattttac aaccattctc cagctacgtg actgacagcc atgaagtgat
    39001 caaagaagtt ttagcaaaac agcttgacaa tgaaaatgat actgatgtaa actcagacac
    39061 aggagtcata gaagcaccta tgacggcatt tgatacacag gctattgata tctcgatcgt
    39121 gcctggtgaa aatgaaaacg agtagaacag aaaagcactt tgttattctt aaagcgagcc
    39181 gatgagagtg gaagttcggt aagacactgc atggtgaaag atcctctact tgagacctgc
    39241 ttttccgaaa ttagagtaag aagcagcggc tgacctcgtt attggtcaca gagagtttgc
    39301 actagataga tgcaactaaa tttgggtggt accacggcat gttcgtccct tgcggctgaa
    39361 catgcttttt tgtgtccgga aaacaaataa aggagtgtat ggttgaatga aaatgaaaga
    39421 aaccttgcaa ttaggaaaaa caaaattccc tatgcgtggt aatttgccaa accgagaagg
    39481 cgagtggcaa aaagaatggg aagaaaatcg aatctaccaa aaaagacaag agttgaacga
    39541 aggaaaacct agctttgttc ttcatgatgg acctccatat gccaatggta atatccattt
    39601 aggacattca ttgaataaaa tcagtaaaga cattatcatt cgttcaaaat caatgtctgg
    39661 ctatcgtgca ccatatgttc caggatggga tacacatgga ttgccgattg aacaagtatt
    39721 ggctaataaa ggcgtgaaac gtaaagaaat gtccatggca gaatacttgg aaaaatgtcg
    39781 tgaatatgca ctttcccaag tagataagca acgagcagat ttcaaacgcc taggagttgc
    39841 aggagattgg gaacatcctt atgttacatt agatccttct tatgaagctg cacaagtacg
    39901 cgtatttggt aaaatggctg aaaaaggcta tatttacaaa ggattgaaac caatttactg
    39961 gtctccgtca agtgagtctt ctttagcgga agctgaaatt gaatataaag atgtaaaatc
    40021 tccatctatt tttgtagctt tcaatgtcaa agacggcaaa gatattcttg atgaagatac
    40081 agcttttgtc atttggacga caacaccatg gacattgcca gcaaaccaag gtattgctgt
    40141 aaatccaaaa tttacgtatg tattggtgga agccgatggc cgtaagtttg tcgtagcgaa
    40201 agatttgcta gaaacagtcc aatcagaaat cggttgggaa aatgtaacag ttctaaaaga
    40261 atttgctgga caagaaatgg aatatatgac tgcaagtcat ccattctatg aacgtgaatc
    40321 acttgtgatt ttaggcgatc atgttacttt agacgctggt actggattag tccatactgc
    40381 tccaggacat ggggaagatg actatatcgc tggtagcaaa tataaactat ctgtagtgtc
    40441 acctgtagac tcaaaaggat tgtttacaga agaagcacct ggatttgaag gtatctttta
    40501 tgacaaagca aatcctatga tcactgatct attaaaagaa aaaggagctt tgctgaagct
    40561 agatttcttt actcatagtt atcctcacga ttggcggacg aaaaagcctg tgatctatcg
    40621 ggcaactcca caatggtttg catctatcga taaattccgt cagaatattt tggatgaagt
    40681 agaaaaagta gagtgggtta tcccatgggg taaaacacgt ttgtataata tgatccgtga
    40741 ccgcggcgat tgggtaattt cccgtcagcg tgcatgggga gtaccacttc cgattttcta
    40801 tgctgaaaat ggagaagcaa tcatcacacc agaaacaatc gaacatgtgg caaaattatt
    40861 tgctgaacat ggatcaatta tctggtttga aaaagaagcg aaagaacttc ttcctgaagg
    40921 atttacccac ccaggttctc ctaatggcga atttacaaaa gaaaaagata tcatggatgt
    40981 ctggtttgat tctggttctt ctcatgaagc tgttttacgt cagcgaccag aattatcatt
    41041 cccagcagat atgtatttag aaggatcaga ccaatatcgt ggctggttca actcaagtat
    41101 cacgactagt gtggctatca atggtgtagc accatacaaa tcagttattt ctcaaggatt
    41161 tgctttagat ggtgaaggcc gtaagatgag taaatcttta ggaaacatca ttgcaccaga
    41221 aaaagtgatc aaacaatttg gtgcagatat ccttcgctta tgggtatcta gtgtagatta
    41281 tgaagcagat gttcgtgttt ctatggatat cttaagtcaa gtggcagaag tatatcgtaa
    41341 aatcagaaat acgatgcgtt tcttattagc gaatacagaa gatttcgatc ctaaaaaaga
    41401 tactgtttcg tacaatgatt tacgttctgt agacaaatat atgaccgttc gattgaacca
    41461 agtaatcaaa gaaatccgag aagaagggta cgacaaatat aacttcatgc atatttaccg
    41521 tacagttatg aacttcttga cggttgatct atcgtcattc tacctggatt ttgctaaaga
    41581 tgtagtttat attgaagcag aagatgatta tcaacgtcgt tgcatgcaaa ctgttttcta
    41641 tcaaacagct gtagctttga caaaattatt gactcctatc attccgcata cagcagaaga
    41701 aatctggtca ttcctgaaag aagaagagga gtacgttcag ttaagcgagt ttcctggtta
    41761 tgaagagttt gcaaaccaag aagaattgat ggatacctgg actgctttca tggacttccg
    41821 tgataatgtc ttaaaagcat tggaagaagc aagaaacagc aaattgattg gtaaatcttt
    41881 ggaagcaaaa ctaactgttt atccaaaaca acaagttcgt gaaatgttaa aagctttgga
    41941 tgcagatatt gcacaattat tgatcgtttc accagactac tttgaagtta tggcagcaga
    42001 tgaacaagtg ccagataacg ctatggtatt tgatgatgtt gctattacag tggaaaaagc
    42061 agacggggaa acttgcgatc gctgtcgcca agttcgtaaa gatgtaggag tagatgaaaa
    42121 acttcctcat ctatgcggtc gttgtgcaaa aatcgttgaa gacttctatc ctgaagctgt
    42181 agctgaagga ttcgaagaaa agtaaaaggg aaaagggggt gtgacatgtt ctttgtcaca
    42241 cccccttttg ttatcaatcg tttaattttc cacgttcacg ataccagtta tctggttgcc
    42301 agatccattc gaatccgtct ttttcaagta gttcgaaagc tgctttaggt cccattgatc
    42361 cagctttgta gttgggaaaa tccggttgtg tttggtccca agcttttcga atgacatcca
    42421 cgatatgcca agattgagcg acttcttccc aatgagagaa gttcgttcca tcaccattca
    42481 acgcatctaa tagtaatttt tcgtaagctt ctgggctatt ttcaaccatt tctgcactat
    42541 ttctaaattc caatttgatt ggttccgttt caaatccttg ccctacttct ttcccattca
    42601 aggataaaga aaatccttca gttggctgaa tatagatcgt tagaacatta ggtggaagtg
    42661 tcgtatcgtc acatggttca tcgacagatg ttttgaatac attaacagga acttgtttga
    42721 atacgatgtt gatccgagtc cctttttcag tcaaacgttt gcctgtacgt acatagaaag
    42781 gaacacctga ccaacggaag ttatcgatag tgaatttgcc tgcgacgaat gtttcagtct
    42841 ctgattgagc atccactttg tcttcttcgc gatagccctt gaattgtaca ccatccaatt
    42901 caccttgagc atattgcccg cgaacgaagt tttctaacac ttcttcttcg ttataaatgc
    42961 ggatagcttt caatgctttg atcttttctg tacggatttc tttttcggaa aatgctactg
    43021 gcggttccat tgcaagtaat gctacaacct gtaaaatatg attttgcacc atgtctttaa
    43081 gtgcgccact atgatcgtag tagcccccgc gatcttctac accgaggttt tcgccaaaag
    43141 taatttggat attgtcgata tagcgattgt tccattgagc ctcaaaaata ttattggcaa
    43201 aacggatagc tgagatgttt tggatcattt cttttcctaa ataatgatca atcctgaaaa
    43261 tatcttgttc tgggaatact tctctgattt gctggttcaa ttcaaaagca gactggtaat
    43321 cagaaccgaa cggtttttct atgatcaaac gattgaagcc attttttgtc ataatatttt
    43381 gtgatttcaa atgagaaacg atcgttccaa aaaattgagg tgccatagcc aaataataga
    43441 cacggttacc gtttaattga tagtgtccat ctaatcggtc agacaattct tttaatgtct
    43501 gataatgcgt tgaatcattt acatcatggg attgatagta aaaatggctt gcaaaggtag
    43561 ttgcttcttc atctgaagga ttcaatgcac ggattgtttc tttgacaact tcacggtagt
    43621 gctcatcgct ccagggacgg cgagcggttc cgattacagc aaaatgctcg cctaaatttc
    43681 cttttctgta aaggcggaac aaagacgggt acaatttacg ctgggctagg tcacctgtac
    43741 cgccgaatat cgtaaacaat acattttttt cattagacat gtggatacac tcctttatat
    43801 tttatcgaca aaaatcgtgc tggccgcctt aaagctgacg gggattttct ttctatcatt
    43861 ttggatagtg atcggtcctt cataagctgc gatgtcaacg atctcatatt cttcgttgat
    43921 attcaggtca atagtgacta agtaatccaa caattctttt tcatcaagca ctcgtgcgat
    43981 acgcactttt gtaccgacag gataggactc caatgtttgt cggcgttctt catggacaac
    44041 ttcctctttt ttaggaatcg atcctccatg aggacaatgt tcaggatgat tcaaatagtt
    44101 ttctaaatga tctgcaagat gttccgaagt cacatgttcc aatacttcag catcatcatg
    44161 gacttcattc cagctatagt ctaaatgttc aactaaaaaa acttcccata agcgatgttt
    44221 gcgaatcaga ctgctagctt tttgcagtcc gcttgcagtc aattgtacac cttgataagg
    44281 ggaatgttct acaagctctt ctttcacaag tttagaaatc atttcactga cagatgcagc
    44341 tgagacatct agactagata cgatttgttt attgttgact ttcgttgtat ctccacctag
    44401 ttctaaaatg attttcaaat aatcttctcg atttggtgtc atattcgatc atcctttcat
    44461 ggtaaaaaac catcattagt aagtgtaaca aaaaaaacgt taattgacta tttttctaaa
    44521 taaaaaacaa aggattttta gacgttttta caacaaaaaa cgaaagatga tagagaagac
    44581 tcattctttc gtttataaag gatatatata tacattggga gggatctatt tttcagataa
    44641 caacttatat gaagtgtctg cagattcgtc ataaagagtt tgttcgggat aagaaaagat
    44701 aagataaaaa ccatactgat cacgtacgac taaacgatat tcatctattt ctaccacaga
    44761 tgtgccaaga gactgaccgt tgatcaaaaa cgtgtaatca gatgtaatct gtaattgttg
    44821 tttttgctgg ctatcactaa agaaccatgt accttgatac tttgagagtc cttctgactt
    44881 ttccgcttgt tttttctttt tcaagtaaat aaaacttgag agaacggtaa tgagtgaacc
    44941 aagaaaatag atcatttttt ttatcaccaa atcactcctt tatgagaaaa taatcgcata
    45001 gacatattct ttcttcttta tttcattgta ccgaataaaa gctaaaattt ctctaagact
    45061 ttcgactggt ttttttactg tttttctaca aattatgata ggatacatag taggaagaaa
    45121 ggtgacataa tttgaagtat cagcaagtgg aaatagcttt ttttattgac cgcccgaatc
    45181 ggtttatagc acattgtatg aaaaaagacg gagaaataat tattgcgcat gtcaaaaata
    45241 caggtagagg aaaagaggtc ctgataccag gcgctgaagt ggctattgta tttgctcctg
    45301 gacctaaacg gaaaaccgcc tatgatctga ttgctgtaaa aaagaagggt gactggttta
    45361 atatcgatag tcaattgcct aatcggctgg caattgatgg tattttagac ggcacgatcc
    45421 ttttaccagg attaactggt ccatttacgg tatacaagcg tgaagtaact tatcttcact
    45481 ccaaatttga tatttattta gagacggtgg tcggacaaaa agcatttgtt gaagtcaaag
    45541 gtatgacact tgaaaataaa gcgattggtg cttttcctga tgcgcccaca ctcagaggat
    45601 tgaaacatat aggagaatta acgtatgccg cacaagatgg ttatgccgct tatgtcttgt
    45661 ttattgctca gttcgaacat cttcatctgg caacgatcca tgaagaaatg caaccagcac
    45721 tagctgatat ggttcgacat gcgcagcaaa gcggagttca aatcctcgcc tataattgtc
    45781 aagtatcggc agatgaggta actgtcaagc aggccattcc atttgatgta gatatccctt
    45841 ttgaagatcc tatacaatag aaagaaggta aaataatgat caacttaggt attatcggaa
    45901 caaattggat tactcatcaa tttgtccaag cagctttaag cacaaaaaaa tatgaattga
    45961 cagcggtata ttctagacat ttggaaaaag cacaggaatt tggttctcat tatgaagggg
    46021 atatcgaatt cgcaacagat ttgaagactt ttttcaatat tactcatatg gacaccattt
    46081 atattgcttc tccgaatagt cttcacttta gtcaagctaa gcaagcaatt ttggcaggaa
    46141 aaaatgtgat agttgaaaag ccagcttttt cgacgccaaa agaaatggat gaaatcatcc
    46201 atttggcaaa tgaacacaat gtgtattttt ttgaagcagc aagaaatatc catgaatcag
    46261 gttttaaaaa gattgccgat tacttaccat taaaagacga gataatcggt gcaaatttca
    46321 gctatatgaa atattcttcg cgctatgacc aagtattaga tggagaagaa ccgaatatct
    46381 tctcgactca tttctcaggt ggtgcattga tggatttagg tgtttacctt gtatatgcag
    46441 ctgttgcttg gtttggaatg ccaaaagaag tccattattt cccaagaaag atttctactg
    46501 gtgtagatgg tcttggatgg gggatcttac gttatgagaa ttttgatgta tcgatccagc
    46561 caggtaaaat cggtgattct tatttaccgt cagagattta ttttgactca ggaacgctag
    46621 tgatgaatgg agtcaatgca attgaacaag cacaatttca tgatcgcgcg cataaagaaa
    46681 tcattgattt ggcggtaaca gctgcagaaa atccaatggc agatgaagca gaggattttg
    46741 ccaatgtcat ggctcatccg aaagatccag cttggggatt gttgtatgaa gagtggatcg
    46801 agctagctag aaatgtgaac caagtgattt atgatttaag aaaaaatggc ggcatcaaat
    46861 tcgatgcaga taatgaggaa gatttttaat gaacgaattt gtacaagtat ttcccgaaaa
    46921 ttggcagaaa aaatatgagg ataaagggtt tatctcacct tctcttattc aacgagcagt
    46981 ttttcagcca ctaagtaata aacaaagtat agtagcggtt tctcctacag gttcaggtaa
    47041 aacactggct tatctttggc ctctactact aaacgtggaa ccaggtgaag caagtgcgtt
    47101 ggtcattttt gcttcttctc aagaactagc tattcaagta gcagatgttg cacgtgaatg
    47161 gggaaaagac aaagagttga aagtccaatc tttggtgggc ggagccaacg tcaaacgtca
    47221 gattgagggt ttgaaggaaa aaccagaaat cttgattggt acaccaggaa gaatattgga
    47281 attgatgaaa gcaaaaaaaa taaaagcaca tcaagtgaaa acaatggtat ttgatgaagc
    47341 agaccagcta tttgacgctg ggaacagcca aatcattgat caaattcttc atcaagctcc
    47401 aacagagtat cagctagctt ttttttcagc gacagcagat cgttcccttg aaagcattga
    47461 aaaaatcact gggaaaacgt ttgagacaat tgacgtgaca gcagaggacg attctcgaaa
    47521 aggactgaga cattactttt tacgtgtacc gatacgaaag aaagatgact acttgagacg
    47581 tctcacgcat atagaagatt ttcatggtct gattttcttt aatcaactga ctgaattagg
    47641 cgtaatggaa gaaaaattgc tgtatagagg tgtaccggta ggaagtctgg cctctgatca
    47701 gaacaagcta ctccgaaaag cagcgctaga acaattcaaa aagaaaatgg tcagagcact
    47761 tttgaccaca gatgtggcgg ctagaggttt agatattaca ggtcttcctt atgtagtgaa
    47821 tgcagaagtt ccgttaagtg aagaagctta tttgcatcgt tcgggaagaa ctggtcgaat
    47881 gggtaatgaa ggaatagtaa ttacactcgt acaagataat aatctaagag atttaaaacg
    47941 gcttttacgt ccatcaaata taacacttga agagattttt ttatacggag gtaagctgca
    48001 aactgagcag ccaaccaaag aagatgcagc tcctgcagta aataaaaagt atgcgaaaac
    48061 tttttctgga aaggagcaga acccagaata taacaaagaa aaaataagaa aaaaagttaa
    48121 aaataaatca aaaaaagaga gaaataaagg agcaaggcgc aaataagcgc ctttttatgc
    48181 tatgattatg aaaacgggaa caaaattggt tgccagagga ggggttatgt gaaagaacgt
    48241 caagaagaga tcttgcagct attgacagaa aaccaacaag gattgacagc aagtgatgta
    48301 gctgagcgct taactatcga tcgaagcaat gcaagccgat atttaagtga actatacaag
    48361 gcccatcata ttgtaaaaac cgctggccga ccagtcgttt actctttgcc aacggaaaag
    48421 tcaaaatctg atgaagtgca tgtcgactct tctacgcaag tgacttttga aacactcgtt
    48481 ggagaaaatg attctttaaa agtcagcata cagcaggcaa aagctgcgat tctttatcca
    48541 ccgcgggggt tgcatacgat tatttttgga gaaactggta cagggaagtc gatgtttgct
    48601 gaatgtatgt atcattttgc aatcgattca gagatgcttt ctgcagatgc gccatttgtt
    48661 tctttcaatt gtgcggatta tgctcaaaat ccgcaactgc tctttggaca catctttggg
    48721 atcaaaaaag gggcttacac aggagcagct caagatagtc ccggtctaat agccaaagca
    48781 gacggcggta tattgttttt agatgagatc caccgtttac cgccggaagg gcaggaaatg
    48841 ctgtttactt tcattgataa aggtatttac cgtccgcttg gagaaagtgc acaagtacat
    48901 gaagcatctg ttcagatcat tggggcgacg actgaatctt cagaaagttt cttatctacg
    48961 ttcaatcgac ggattcctat ggcaatcacc ttgccgaatc ttgcttcacg ttcactggat
    49021 gagcgttatg aaatcatctc tctttttatc aaacaagaag cgaatcgttt gaatcaacgt
    49081 atcgatatcg aaaaagaagc gattcttgcc ttcatgcttt atgatgcgga aggaaatatc
    49141 ggtcaagtga aacgagactt gaaactagtc tgtgcaaaat cttttttaca ttaccgtact
    49201 catcatgaga aaaagctaat cattcgaaaa gaagaacttt cccttcaagt acaaaaagga
    49261 ttactgaaaa tcaaggaaat accggaacgt ctcgaccgat tcatggacag caaaagtcag
    49321 tatttgacat ttgaaccagg atttgctgat gttgtctggt cacaagatcc agaacgaaac
    49381 atgcaggtct ataacgatat tgaggaaaaa gtcacttctc tttccgaaac cggtgtggag
    49441 aacattgatc tagagaccct catttcaaaa gatgtggatg cttatttcca gacatatgtc
    49501 aaagaattga ctaaaagttc gattcccaaa gatcttttgc cagatgaaat ctggcggtta
    49561 accaatcaat tgtatgatgt ggctgaaaaa cggttagacc gtatttataa tgaaaaagct
    49621 cgttttgctt ttgctttgca tctgcaaagt acattggatc gtgtgagaga aggtcatatg
    49681 atcgtccacc cagatttgaa taacgtacgg aaaaatttta agagggaatt ccaggtagca
    49741 atcgatcttt caacgatcat tgaagaagaa gaacaagttg agattccttt tgatgaaatc
    49801 ggctttatta gtatgtttct ttctatcaat ctaggagaaa gtgagcctgt taaagaaaac
    49861 aaagtagatg ttctcatatt gatgcacggc agacagactg cttcaagcat gttggagatg
    49921 gcacaagaac tattaggaac aaaagtaggg aaagctttta atatgccact ggttatggaa
    49981 gttcaaacaa tgtatgaaga agtgttacaa tatgtcaaaa actatcaaga gcatttgacg
    50041 aatggcctac tcttgttaac agatatggga tcattaaaca ccttcagtga tttgatttat
    50101 gaagagactg gcattcggac gaaagctatc acgatgacaa gtaccatgat tgtgatagaa
    50161 gcgatacgga tggcaagtgt tggaagaagc ttagaagata tttatcaaaa tatccagctt
    50221 tcctttgaat cgatcgtacg tgatcagttc aaagcggaaa agtctgaaac tttacagcgt
    50281 aaaaaagccg taatcgtgac atgctttact ggtgaaggag tagctgccaa attatatcag
    50341 cgtattatgc cagtgattaa tcaaaataag gtagaactga tccagatgca gtttttagaa
    50401 cgtgaatcat tcaaaaaaca catcgatgcc ttattggaag aatatgagat caaagcaatt
    50461 gcgggaacag ttgatgttga ttatcaaaat atcccatttt tttcagccta tgacgttttt
    50521 gatgatgaaa aactaaatat tttaaagcgt atagctgatg atgagatccc gacagctaaa
    50581 attgtcgatt cacttgctgg atcattaagc gatgtctttt ctattgatga actgatccgt
    50641 tcattgcaaa agacagttca gcagatccag accgatttgt cgattatcgt ggaacctgga
    50701 gtagatactg gaatcgttat ccatttagcc ttcatgttag acggattgat caaacaagaa
    50761 agccatcggc aatttgagaa actgtctatt ttctcaaaaa tttatcgttt ggaaatggat
    50821 atcgttcggg caaacttgat ggcactagaa cgaaaatatc aggtaaaaat tccagaagat
    50881 gatatcgcat ttcttacaca aatgtttctt gaaaataaaa taaaaaaatg aacacactaa
    50941 tcatactgtt tacacactaa acatctgtgt gcgcactata aaaaagagct aaaaagcatg
    51001 aaaacgctat ttcagctctt ttttttattg gcatgcttct tgcgttatat aaaagtgtaa
    51061 aaaaataaaa ggagtgttaa aaatggcaaa aaaaacaatc atgttagttt gttcagcagg
    51121 gatgagtacg agtttattgg tcacaaaaat gcaaaaagca gcagaagaaa aagggatgga
    51181 agccgatatt tttgcggtct ctgcctcaga tgcagataat aatttagaat ctaagaatgt
    51241 cgatgtatta ttattaggtc ctcaagtacg tttcatgaaa gctcaatttg aacaaaaact
    51301 tgcgcctaaa ggtattccat tagatgtcat caatatgcaa gactatggca tgatgaacgg
    51361 agaaaaagtt cttgcacaag cagaaaatct aatgaaataa atcaagtatg cagttggggg
    51421 tataacaacg tggaagatca acaaaatcta gaagccatca tggggttaat catgtttggc
    51481 ggtaatgcaa agagcgatgc aatggaagcg attgcggctg ctaaaatcgg tgattttgag
    51541 ttagcggata ggaaaatcgc tgatgcagaa gaatcactta tacaagcgca tcatgcacaa
    51601 acagacatgt tgacacaaga agcacaagga aatcatatgc aagtgacatt attgactgtt
    51661 cacagtcaag atcacttaat gacatctatt gcgtttactg atttagcaaa agaaatcatc
    51721 gaactttatc gtcgcgtata cagcgaataa atacaacttc ttttttgaac ggaagaagaa
    51781 aaatttttga acggattttt tattttgtta taaggagaac tctctttata taaaaaactt
    51841 ataggaggaa gtaaaaaatg aacggactat caagttggat ggagaaatac atcctgccgg
    51901 ttgccgcaaa aatcggagcg caaaaacatt tagttgcttt gcgtgatgct tttatcggca
    51961 tactgcccgc aacaatggcg ggatcagtcg ctgtaatgat caatgcaatt attcgtgatt
    52021 taccgcaaca gtttaacagt acctatgctg acagtttagc agcagacaaa ggaatctttg
    52081 ccgtattgaa tgtcatcatc ggaatcaatg gttttgtctg gaacggtaca ctagcaatcg
    52141 ccggattgat ctttgccttt tcttgggggt ataatcttgc ccgagcttat ggagtaaatg
    52201 atctagctgg ggggatcgtt ggtttagcta ccttgattca aggtatttcc tttggtccag
    52261 cattatcagc agcattagat gtgaatgttc cttcaaatgt cgcagatgca atcaatagtt
    52321 ctgagattgg tgcaacgatt gcagatggca cactgtcagt tggattatgg ggttggctaa
    52381 aactagatca tttgaatgga aacgcttatt ttacagttat gatcatggga gctatttcag
    52441 tcattatttt ttgtaaattg atgcttgcca acattacgat caaaatgcct gattcagtac
    52501 caccagcagt atctaaagca tttgcagcca ttttaccagc gacgatcgct ttatacgtca
    52561 ttgctattat caattatatc gtaggtcgtg tagctgatgg gcaactgatc attgatttgg
    52621 tgcaaaaata tattgcagaa ccattcctag gattatctca agggttggga gcagtattga
    52681 tcgtcacagt atttgttcaa gtattctggt tctttggtat tcatggatca aatgtattgg
    52741 caccagtgct agagggaatc tggggacaag cacaactaat caatattgat attttccaaa
    52801 aaggttataa cggaaaaact ggtacaccag ccgtgttaga tgcaatcgaa gatggaaaag
    52861 cttatatgtg ggtccgcgga tcgttcgatg cttttgcatg gtttggcgga tcaggcggaa
    52921 cgatcgtctt actgatagct atcttgattt tctctaaacg tgcagattat ctaacagtag
    52981 ctaaattatc cattgggcct ggtatcttca atatcaacga accagtgatg tttggtctgc
    53041 caatcgtatt gaatgcaatc atgtttatcc cattcttgat tgctccagta gtagcaacag
    53101 caattggatg gacagctact tatcttggcc tagtcgctcc ggtatcgcag caagtcacat
    53161 gggtagtacc gccgttctta ttgtcattct tagcaacagg agcggattgg cgggcaccga
    53221 tcgtaacatt agtatgtatg gtcgtgactt tcttgatttg ggcaccattt gtcatctctg
    53281 caaacaaaat ggaccctgcc gcaggcgaac aacaataaga tgaacgtgag gagcgggacg
    53341 ctttaagttt cgttcctcat aatgaatttt cgaggaggaa ctgaaatgat tacaattgcc
    53401 agtgcaatgc aacaagatga aatcaaagaa ttgttagaag gatacaatga agaaggaatg
    53461 acttttacat ttaaagaaaa acaaggaatc aagctgttct ttgaaacaag tgcagaagat
    53521 ccggaagttg cggctaaaaa agcaaaggaa ctaatcaaag cacagccttg gggaacagtc
    53581 ctttattttc aatcaacagc tgtttagaaa atggtttaaa aagataggat ggttgagatg
    53641 ataaaaaacg gtttattttt atgtagtatt ggttctttga tcgtgttgta tagtttgaat
    53701 ccacattcgc aaaggtatga tttgtatagt atggtcacag gtctttttct aacaggatta
    53761 ggaatctatt tcttcatgaa ggggaaaaaa agagaagaag caaaggagaa aaataactaa
    53821 tggaaatcac gaaaaaatta aatattccag catcgttttt ttacgataaa gttatggact
    53881 ctgtcctttt cgatgtacgt aaagcgaccg gcaaatcagt aactagaaaa cagctgaaaa
    53941 atttggagta cgtcaaacaa ttctcgcaaa ataaccgggc tcgcataaaa atcgaagaag
    54001 tcattgaaaa ccagtcttat aagtttcgta catcgacaac gaagaatgaa ttcgtcgttc
    54061 attatcaaat caaaccattg gacgattcga cctgtgaggt tcattacaca gaaaaaatgg
    54121 agtcttatgg catgcttcaa aagttgaatg atatgctttt aggaacaatc ttgatgtatt
    54181 ttaaacggag acgtttcaaa aaaatgctag atatgatcga agcaacgtat taaatcaatg
    54241 aaacatggta ctatttagtt attgaaaaat gaagtaagct agaaggaatt tttcatagga
    54301 agatagatct ttcctgcgaa tcctcactag cttttttgta ggaaggggca gcaaaatgac
    54361 aaacaaagta agagagctag gtgtatcttc gattgaggaa atgtttgatt tagccactta
    54421 tgcatttaat ggggcagata cacctgaaag gcgagaacgt tttcgtacac ttgcggagaa
    54481 ttcttggaat tacggatttt ttgatgagga ggatcggcta acaagtcaag tcatggcgac
    54541 cccttttcca gtgaattttt acggacaaga gtacctaatg gccggcattg gctatgttgc
    54601 ttcttatcca gaagcaaggg gacaaggcgg gatcaatcag atcatggaaa agatccttga
    54661 agattgccgt gatcgtaaag taagcttatc ttatctggcg ccattctcct atcccttcta
    54721 tcggcgctat ggctatgaac aatcatttga taaaatcagt tatcaactaa acagtcgtga
    54781 tgtgccgttt atcaaaaaaa aatctggaaa aataaagcgt atggattttg aagatgcaaa
    54841 agctgcaatc agaagaattt atgaacagat gccggaaaac caacgagctg gtctgaagcg
    54901 cgaagactgg tggtatacgt ataaattcaa gcaaaaaggc aattaccagt ttgctttgca
    54961 ttttgatgat aatgaggaag caacgggata tatcgtttat cagcttgcaa cgtcttcctt
    55021 tattattgcg gagtggggat ttttggatca tgatgctttt tgcagccttg ttcgcttcgt
    55081 aagttctcac aatggtgctt ttgaaacatt tgaatattca tgcggctacg gcggtaatga
    55141 tcaaaattat ctattagaaa atccatttgc ttctgtaatg atcacacctt atatgatggc
    55201 gaggatcgta gatatttctt tgtttttgga aaattatcca tttaaaaaga gacaagctgc
    55261 atttgcccta caaatagaag aagatcatta tgcgaaatgg aatgaaggaa tcgtggaagt
    55321 aacaatcgaa aatggaaaaa atcatctctc aaaagtagaa caaacaaaac tcccaatcgt
    55381 tcgaggaagt atccaacata tcacgcagct attattaggg tatcgtaaag tggaagagtt
    55441 ggtattccaa gaaagaatac aggtgacaaa agaatatgaa gaaacgttaa gctcaatctt
    55501 gccacagcaa cagccaattc ttaatgacta tttttgataa aaaacgggtg atgacaatat
    55561 ttttgtcacc acccttttgt ttttcatttg gcatttgaag gaaaatgtta aagtaaatcc
    55621 tcttttttcg taaatttgaa ttttttgttt tcttttgttt tagggttttc ttttttgtgg
    55681 tcttggattg cttctttcgt aatcttttcc cgattttttt tagatgaatc taagcgttct
    55741 gcgtatactt tttcttttgg cttatcattc attggaaagg acctccctac attatttcat
    55801 tctacctcta gtttatcatc tgttaaggac tagtggaaac gttttgccta acttataagc
    55861 tgattttttt agcagataag cttgcaagta aaaaacaaac aagctacaat tgatttattg
    55921 aaattgttcc tgtagctcag taggatagag caatcgcctc ctaagcgata ggtcgctggt
    55981 tcaattccag tcaggaacgt ataaataacc cctgtatcct ttgcggtaca ggggtttgtt
    56041 ttgtatttgt gccaaaaatg tgccaaacta gttatcattt ttatataaac tatcgaacac
    56101 agtattgatt ttttctttat cctgatcttc aagctctcga acaatatgaa gataagtaga
    56161 cattgtagtt tctaaactgc tatgtcctaa acgtttcgat acgctaagta tatttactcc
    56221 ttgataaagt aaaatagatg catgtgtatg ccttagtcca tgcaaagtaa attgcttttc
    56281 aatccctaat tcttttaatt ttttgcgcaa atatttgctg acggcgtttg atgaaactaa
    56341 tccatttttt aagttgaaaa aaacaaaatt atgagggttt ttgatttcaa aattctcgaa
    56401 taattctttt tgattgattt taaacttttt taagagatca atcgtatgtt tatcaatgga
    56461 aattttccta tttgaagttt cgttttttgt ttttccccat tcatttaatt tataattcca
    56521 tgttttatta atagtgatga tttgatcttc gaaatcgata tcttcccatg ttaatcctag
    56581 aagttcagca aatcgcattc cagtggcacc agcaactaac acgagcatag gagaagagta
    56641 ctgcgcagaa aggttttctt ctacgagttt cattaaagat ttaaattgat cataatctaa
    56701 atatttatct tcttttggct tcaatgaatc ttttcctttg attactgctt ttctagttgg
    56761 atcaaacgga attaatcctt cttctacggc atctttcaac gacgctctaa tatggttatt
    56821 aaacttaata acggtagatt ttacatggtc tttagcatac ttatttaaaa agcgttgata
    56881 tcccactcta tctaaatcag aaatcaatac cgctggcata tatttcttta tgttcattaa
    56941 cgtatcttcg tattttctat aagtgatagg agatactgtt ccttctttat aaagttgcat
    57001 ccaatcctca aagtaatctg ataataatag atttttgcga tcccctttaa ggcctttgtt
    57061 caagttatat tctaattcgt tggcggcatc ttttgcttct ccttttgtct taaatcctga
    57121 ttttcttatc ttcgtgtatt ttccgtcatc ttttttgtat gaaatttcgt attgccaact
    57181 atttccacgt ttgactaatc ttgccataat tgaatcagct ctctttctct gatacaatag
    57241 gaactataaa gaagcccatt gtttgggttt tattattttt tgcacatcct ttttgcttgc
    57301 cggcgcaagg atgtgctatt tgtcgtttta atggtataat tggatgtgta ttagatcatc
    57361 caatcagagg tgtttattat gattaaagtg atttttaaaa gaataactga acttccagag
    57421 tttagattat ttgttgatta ttggtatgtc tggtttttta ttgttgcatt gctgataggt
    57481 ctagatgtca tattagaaag aaaacttaag taagagttga gttaataaat tgaattccta
    57541 aatgagatat tttgtagccc atattttgtt tgccgacatc acctaatact atggagctaa
    57601 tcgttttttc taacagacca aaatcagata atctatttaa gctaccatct attagctctt
    57661 gtgaatagcc agacatgctg atatttccag tgaaattttc gtttccacga ctcattaagc
    57721 atgctaacaa ttgaatctca atcgatgtta attgattcag tacaagaaga taatactcct
    57781 cgttatccca tgaagcgttg ttaattcgaa gtaaacaatt cttataaaga tttttataca
    57841 tatctatttt attttgtgcc tttgattttt ctacctcgtc atttatccct tcgaatattc
    57901 caatgagttg gtccttgttc tctaagttga aaacatcttc tggaatttga tcgcgaatgt
    57961 tttctaatga ttcgtttaaa tttttgtaga atttctcgat gcgtttgaaa cgcttctcgt
    58021 ttttagaccc aaaataaagt gactgcacaa cgccaccaat ataaggaatt gctccaatac
    58081 cgccttcaac tattaattca agatattctt ttttggttag tttttcattg ctattatcca
    58141 tagttacctc ctattttgtc atttccttta caagcattgt gactcctgat ggcactcttt
    58201 tgtataggtt ttattattgt gcacaatcta actcttagtg gggcgtggtt catttatttt
    58261 ttacttactt tactattaat catatcccat tgagcatagg atttttctat gttcgatcct
    58321 cttgaactaa tttctcctgt aaaagttact ttatcgccct ttgtaaaggt atcagcattg
    58381 tttaagtcct tcgcaaaaat tacatatgaa actttaggtg ttgcagaaat atcattccaa
    58441 cttttatcat cgtactcttt gtctgctata atggctattc tagtagtcat tgattcgata
    58501 acagttcctt caaaagtata tgttttacca ctaatatatt tagtaaaagc tgtattttgc
    58561 tcagtagctg gagtaataga ataataacta tctaagaaag caccccagtc atgattattt
    58621 gtctctaaaa attcttcaaa ttgagttagg cttttattgc tgctgttaga tgtagtagtt
    58681 tgagtatcag atgatgagct ttcctgtttg ttattgtcat ttgcctcgtt tgatgaggaa
    58741 agcgagaaac ctacggtagt aaaaataatc ccgataataa ggagaatcat aggtgttttc
    58801 ttatttgttt ttttgataaa tcttacaatt aacatgatta aacctataat aaataaaaca
    58861 ataccagtaa aaccaaatat accgtccatt aatagatcct ctttctcttt tgatattgaa
    58921 tattataaac caagcaattc ttttttctta aaatcgaatt cttcttgatt aataatccct
    58981 tcatctaaca actctttata ctttttaatt tcatctgcac ttgaaatttg tgtttctttg
    59041 gaattattat ctaatataga ttgttgcttc tctatatatt tttttaaatt ttccatttca
    59101 ttccaatatt tttttgtaaa cataacggtg ttttcatctt tcgtggccgc taatatacct
    59161 ccgcgacttt cgtttccgcc tagcaaggta aattgtatat aaccattact catacctggt
    59221 ttttttaatt gtacggctga tatattttta aaggggatag ttttttctcc tttaatacct
    59281 tgattaacta aatttataaa tccttttcta ataattgaaa tagaatcatc agttacttta
    59341 atcaaggttt ttcctggaga ttttattaaa atctcttttt ccattttttc ttcctcattt
    59401 ctgtgatatg attttttttg tagaagctca tatatgagga aagagcccgt gttgcagcac
    59461 gggctttttt aatgttttgc tgaaatcggt ttttttaata attcttgatg tattcataca
    59521 tattgccttg cgtaagaata ttttttctta aaatagcatt ggcagacagc ataacaagtg
    59581 tatctgagct tattctgaat agaataatac tccataaatt tttcgagatt aaactgagat
    59641 tcatcagtca gttcgttctc aatatagata tttaataaaa ttagaatagc tattttatct
    59701 gcttctgttt caaattttga gtgaaaagtt gtagaagtat cgtacaaaac tgaaaattca
    59761 aaatgagagg cgctgaaatg tgcaagttca tgagataaat gaaaggcttc tgcagtttca
    59821 ccgtatagat tttcattcaa aaaaatgatt ctgggttttg gatagtagaa accaggctct
    59881 ttcatctcca tataaactac tttcaaattg tattcgctca acatttcttt caatttcaaa
    59941 tacatacaaa ccatcactcc aactattcat tttcctctaa agctttagca attgcaatcg
    60001 ctttacgcat tgtctcctta gatatttctt ttccatcaaa agaaaaaaca gtatcgtctt
    60061 ctgataaatc cacatgttta ggggtttctc tttcttctct acctagaagg tagtctacag
    60121 agacatcgaa atagtcagca atccgactta attcatctga attaggagta ttatttttcc
    60181 actttgctag ataaccgtta gaatatccaa aattaatttc taactgccgt atagatatct
    60241 ttttcctctt cgccaagtct tttattattt cataggtatt catcgataaa acaacctttc
    60301 taaatgttta caaaaaaagt ttagaaaaat acgcagaaat aatttgacta attctgagta
    60361 atgagctata ctatatcttg taaacagatt taacaactaa aaagacaaca aaaaacacta
    60421 ttgatatgta aatgcagacc gccaagaaag ctttaaaatc aatgttttta tgtcttattt
    60481 aattatgctc ttagtataga gtattactca gatactgtca attgaattta gaaaaaagtt
    60541 gttaaatttg tttacgaata taaaagaaag gaatgagaaa tatgaacaca ccgcaaattt
    60601 ttaatttcga acaaaacgaa gttcggacaa ttttagtaaa tgatgaacca tattttgtag
    60661 gcaaagacgt tgcgagtgtt ttgggttatt caaacactaa agatgctttg tcgcggcatg
    60721 tagatttgga agataagatg gggtcgcgaa tcacgacctc aggtcaatca agagagatga
    60781 caatcatcaa cgaatctggt ttgtacagtt taatcttaaa atcaaaactt ccctctgcca
    60841 aaaaatttaa acgttgggta acaagtgaag tgttgccagc aattagaaaa catggaggtt
    60901 atctaactcc agaaaaagta gaagaagctt tgcttaatcc agatacaatc attcaattag
    60961 caactcaact aaaagaagaa agaactggaa gattaatcgc agaacaaaag attgcagagt
    61021 acgaacctaa aatctcctat ttagatagca tattatcttc tacagattca gtaacaatta
    61081 gtcagattgc agcagattat gggatgtctc cacaacagat gaataaatta cttcataaac
    61141 taggtattca gaaaaaagtc ggtaaccaat ggttattgtg caaaaaacac atgaaccaag
    61201 gatacacaaa atctcataca actgagatcc cgaaagccga tggtggcact aaaattgtaa
    61261 tgaataccaa atggacacag aaagggcgtc tatttatcta cgaattacta aaaaaagaag
    61321 gatattaccc tcaaatggat ttagaggaaa ttggttagaa aggagtttta gtatgactga
    61381 cattgcagaa atcactcaac gagatagaga aaaaatcaaa gaatatgtcg aaagttcaaa
    61441 gttcttaact tacaccatgc ttgctgaaag atttggaatt agcaaaagct acttatcttt
    61501 aattttaaac ggtaaaaaga cttctgcaga agcaaacaga attatagatt cgattatcac
    61561 tatgtacgaa ttgtaaaggg aggaacagct aatgcaatat ctagaagcaa aaatcccaat
    61621 tccagaaggc tatgtaatta tctcccaagt ggattatgag gagttaaaaa aagctgatga
    61681 tactggtaga tggatgacgt tgccagaagt gctagaacgg attaacagaa aatatgattg
    61741 gtttacttct agagttttaa agaacccaag atatagaaat attatcgata tcgagaaaaa
    61801 caaaaatgga tttgtctatt atccagttga aggaagagac acatatctat ttttaagaag
    61861 taaaacactt gaatttttag aaacaaattt ttcggaaatc ttaaggaggc aagcggatgg
    61921 gaaaatttaa tagagcgcta gtgttcagcg caccgctaat catctacgct ttaggacttt
    61981 ggggaagcag gcaagcgttg ataggaacga ttgtttacat ggtttggatt tttatggggc
    62041 ttgatgaagc tgaagctgag tacagagcga aaaagccaac cgagggggct gactaaaaat
    62101 gaatagaaaa gagaaactag aatgtatatt actattactc agtttaattc tttcactaat
    62161 ttctctattg ggaagtttgt atttttgata tcaacaattt tgtggatttg ggttctattt
    62221 agagtaaata tcatttttgt ttggtgatta aggagtttat taaaattaat tttccctact
    62281 tcaaatgcaa ggtaacaaga tatagcactt ttaggaggaa tatttagcgg tacagcttca
    62341 gagtatattc tattatcatc gactgatcct cctttagcaa ttaatttctt aaatggagta
    62401 gctgaccatc tgcggtttaa gttagcggat gaaagttcta aattaactaa catagctggt
    62461 tctgttgaat agttagaaat gattactttt gtataaatca tatctgcagc gaagtaagaa
    62521 gcattaagtt caacttctag ttgagggcgc attcctttta tttttatccc tgttaaaaac
    62581 gtactcaata taaaacttat tattgacatc cattgaaaaa ttgttaagtg aaaaaaattc
    62641 aaaataaaca ccaccagttt ttaactaaat tataccaaaa aggagagaag aaataatgca
    62701 agaattagta attttgaaaa ataaagaagc tgtgactacg agcttacaag tggcagaaag
    62761 cttcgagaaa aaacatcaac atgttttaag agatattgat gcactaaaaa aagatgtgtc
    62821 caattttgga cagatgtttg tagaaggtaa tgaaccagat tcatatggca gaaatcgacg
    62881 agttttcttc attagtagag atggattttt cttgctggct atggggttta caggaaagaa
    62941 agctatctac ttcaaacaaa aatacattga agcattcaac gaaatggaag atgttattcg
    63001 caagaatact gttcctcaaa caattgaaga tatgatgatc tatcaattag aagaaatgaa
    63061 agatgttaaa aaagatgttt ccatgcttaa agatactatg cgaattagcg gacaacaaga
    63121 gtttgaaatt aagcaaaaag gaaatatgaa agttatggga gttctagggg gaaaagaaag
    63181 ccgagcttat gaagaaatca gcaaaaaagt attctcaaaa ttttggtctg aatttaaacg
    63241 taccttttca atcccaagat atggcgagtt acctcgtaag agattcgatg atgctgtttc
    63301 atttattgaa atgtggttgc cagaaactgc gatccgtatg gaaattgatc aactgaacag
    63361 acaacagaga ctttttggtg atgacaatga atagagctga agcgctaaga atagggacgg
    63421 caattgctaa ttgctggtgg aaatactata aaccaatcat cctaagccaa caacatattg
    63481 acaagcaaaa agcatggcaa caaataaaaa agtgactccg ccggcaagca aagagtcaca
    63541 aagaaaacac atcataagga gattttagca tatggaaaaa gaactttcca ctctagatca
    63601 atatttgatt gatcctgatt ggggcaagcc gaaaattgag gaaacaagtg gtcgaaaaat
    63661 cagacgaaat cttttgacga atgaagaact agcttgggat caagatgatt taggcaacca
    63721 tgtaactatt tgggatcatg tttatcttat ccatctatcg aagcattcga ataaacctga
    63781 atatatttac gtcatcgaag atggcttgat tgatgcgcta gaagagtacg acagagataa
    63841 cttgattgat atctcttatt acggaccagg taagaaatac attgctgaaa tggaggcaga
    63901 atttgatgag tgaaatcaaa gggacaacga actttgaaaa actttttagt cgtaagttaa
    63961 ataaaattct caagaaaaaa ggaaattttg attatttatc ttgggctcac gcgtgggaga
    64021 ttatgaaaaa gaatgatcca caggcaacgg taactattaa tgagtacaaa cactacaggg
    64081 ttgtttctgg aactcatcaa gactttcttg ttgaggaata taaacctttt cttatggatg
    64141 aaactgggac ttatgtatct gtctcagtaa cggttaaagg acacacggaa accgaattat
    64201 ttcctgtttt agattatcga aaccaaccag ttgttaaacc aaatgcaatg caaatcaata
    64261 actcattgaa gcgatgcttt gtgaaagcat tggctctaca cggactggga ttatatgtat
    64321 ttcaagggga agatattcca acaccaccta gaatcgatac aaagaaatta aacatgctag
    64381 agacgattct agaagctttc aatgagcaga tgggtaaaga tatgaccaaa accttaatcg
    64441 aatatgttaa tgagcagaca gataaattag ggctcttagc tgataacgtt gaaactattg
    64501 aacagttaag ctatgagcaa tgtgccttga tggagcgagc aatagcagct aagagaaaag
    64561 aattagataa gaagtgatat gagtgtttaa accattaatc gattcatatt cagcggttct
    64621 gaaaaagttc aaaggaaaag acataagcgc aaccatcaat gaggaagtga acattgatcg
    64681 actaaagacg atgtatgacg gctacgatgg tgatcgagtc attgaaattc gttttattga
    64741 tcctagacgt ttcaccgtac agcaacgaaa cttcatctat gcgctgatag gcgatatttt
    64801 tatcgataca ggcatgccaa cggacttctg gaaggaattc ttctactttc gttttgaagg
    64861 tgtcacaggg cgcaaaataa gcctgaaaga cgaatcgaat acaactgtga gtgatgccaa
    64921 tgtcttagca aatatcatct tagatttcat ctttgaacat catattcctt tcaaagaagg
    64981 ctatgagatt ttacctgcga atcaagaata ttacttctac aaatgcatca caaaaagagt
    65041 ctgctgcatc tgtggcaaaa caggagctga catcgatcac tttgacaaag cgctaggaag
    65101 acgaaagcgc aaagaagttg atcatgcaga gtacacattt gcagcactct gcagaatcca
    65161 tcacacagag aagcacaaaa taggtgtgat taatttcaaa aataaatatc aaatcaaagg
    65221 gatcaaatta aaccagaaaa caatcaaaaa gttaaatatt ggaggggaaa aatgacagaa
    65281 catcgaagtt attatgcgat tataccagcc aacgtaaggt acgacaaaag acttaaacca
    65341 aatactaagt tgttatacgg agagataacg gccttgtgta atgaaagagg cttttgttgg
    65401 gcaggcaatg agtactttgc agatttatat ggtgtgaata aagagaccat atcgcgatgg
    65461 gtaagtgatt tgattaagtt tggatacttg aatcgggaaa tcatttacaa agagggtacc
    65521 aatcaaataa tcaataggta cctacgaatt aatcaatacc ctattgacga aaaacgcaat
    65581 acccctattg acgaaaaagt caaagataat aatacatcta ttaataatac atttaataat
    65641 acaaaagaat atataagaga gttaccgcct tcgaaaaaat cgaaggctaa gcccgtccgt
    65701 cataaatacg gagagtataa aaatgttctt ttgtcagatg agcagatgga gaaactcaaa
    65761 acagaattcc ctaatgatta ccaagagcga atcgaacgac tgtcagagta ttgtgaatca
    65821 tctggtaaga cttataaaaa ctatttggca actattcgaa gttgggcaag gaaagaaaaa
    65881 agtgaaccta agaacgcaag cagtggatac aagcgcacag gaagacgaga gaagcttcct
    65941 gaatgggcaa tcgaccaaga agcctatctc aagaaaaaag cgctagaacg agctaataga
    66001 caatcaaaag caccattcta agaggtggaa aaatgaagat cgattatcta gaactaatta
    66061 atgaaatagc gaattataaa aagggcgagg aattagacgt cctgagagac gtatatgatc
    66121 aactcgaaga agctggaatt gaaggaatta agaatgatcg ttcgagttgg agtaaactca
    66181 gatactattt cgcactctat atcgatggaa cgcaattaag aaatttagca tataccaaat
    66241 tactattcat tgattgtgtt aaaggcttgc aaaaacatct taatgaactt gagcaggtgt
    66301 aaacaagatg gacctaaaga catttacagc acagatcgaa ttaatgcatc aagaagcttt
    66361 aagacaaagt gtgtcgtacg aagacaagtg gctcaacaca tttcatggcg gacgtgagag
    66421 cgcacttgat caagtactca aattactgaa aggagaatgt cgggatggat aagaaagcgg
    66481 caatgcagcg aattatcgaa ttgacttatt cagaagattg gcaggaagat aaaaaaatag
    66541 ttgcagaagt ccaaaagctc ggtaaatcaa tgtggactga aaagcccaaa cggagaacgc
    66601 cgagaaagat tgcaatctgg catggtgatc gaattctagt aacgggtacc gctaaacagt
    66661 tatctgaaat tactggtctg agcaaaaata ttatttggga tagagctagg agcttatgga
    66721 ttgattcaaa aggaagacag tttaggtatg tggaggagaa ataatggacg aactaatcgc
    66781 gaaagtagag cagtgggcaa aagataaggg attggatcaa gcggatttca gcaagcaaat
    66841 gttaaaaacg gtcgaagaaa tcggggaagt tgccgcttct ctagctagaa aagatgaaca
    66901 tggtttaaga gacggaattg gcgatgtagt agtaaccttg atcatcttgg caatgcaaaa
    66961 tgatatggat ttatacgagt gcttggattt tgcttatgac gaaatcaaag gtcggactgg
    67021 aaagatggtc aatggtgttt tcgttaagtc cagtgacctg aaataattcc attaatggaa
    67081 gaaataactg aataggagga tagacatgat tgatgcaaaa caagtgcaaa aacagaaaga
    67141 tggaatgttg atgtttgaag catatgttct accatttctt aatcaatttg aagttttgga
    67201 atgctctgcc agcggagaag aattggagta tgttgtaatt cgtgaaacca aagaaaacgt
    67261 tcagaagcta aacgaatttc tttgcactat taactgttgg gatatgatag ctccaggatt
    67321 tttatgtcca gctatgggag aatttttgga atattgtcgt cttgaagatg caggcacttt
    67381 ggatttagct tatctggtat acaactacct aaacatcaac acagatcatt tgtggtttgg
    67441 cactgccgaa agaaaatggg tagtccgcta accaccaata tcaatgaaaa aaggcggttt
    67501 cctgaaagtg gaattgccgc cattgctgta aggttcttta cgcgactcaa ggtcacagaa
    67561 atataaatgc aaatctcttt tgaagtgatc caaagctctc ggaaaatgga agttttttgt
    67621 ttcaaagaat aaatgagatt tgcgtcaaga acctgagagt tatttccaaa aaagcttcca
    67681 aagaaccgaa tgagctaagg acatcatgtg taaacacata atatagctct cctttcacgg
    67741 ctaatcataa catgaaaaat attcgatgtc agtaggaaaa aaggtgaatt atgaaaagaa
    67801 tattaaatta tcccggcagt aacagattct gcaattaaac tccgaagctg atgtatcagt
    67861 atcaactgta gaatattatg agcgtggaga aagtcaagca gtcacaaatg taaaaatcga
    67921 taacgtcaac ggtcttatct gtttagatga aggcgatagt atgaatgaaa ttgctgcaga
    67981 ccatgaatta tcagaaactg ctttaattga tcaaatcgaa ttagctagac aatactttgt
    68041 tccatatgca gatacctggt ccaagcataa gaatgacatc atttttccag aggaacaatg
    68101 agagcaactg atccagtaat tatccttgag gaagccaaat ttatttggac tcacgaagag
    68161 atagagcaag cacgcttgct cttttctcaa ggagttaagc cgagcaaagt agctgaaata
    68221 atgggtcaaa agattcttga tgtcggattg cttttgctcc atctagcaga aaaaatttga
    68281 tttgaggtga aaatgatgat tcaacttgca ggcatccaaa cagggaaaat ttatttttct
    68341 ggagaaagca aaagcgaagc caaccaatgg ctattgaaaa cttacacgaa caataagaag
    68401 ctaaggaaaa aatatcctga tttgttgcta aaggatgatc agattatgcc ggaaccgatg
    68461 attttgaccc gtaaggaggg aagttgaaac taaaaaacca gccgtgtggg ctggagttgc
    68521 tatttctttt taataatgag tttttctaaa tttaattcat tctcacgagt ttgcgtccaa
    68581 taatcagaat aatattttaa ttgtttaaga gtaggaatgt cgtcttcggt aaaattagaa
    68641 aataattctg gagaattatc tttttttaat tgttctaatc ctgattcttt aaaacgttgt
    68701 tcaacgagtt ttactaaatt gttgatattc atgataaatc acctttttaa atttaatttc
    68761 gatttgatta atcgatacaa gtattatatc aaataaaaaa gctgatttag ggggtcttac
    68821 aaaaacacta aaattttttc aaaaagagga ggaacggtgg tgaaagtcag agaacaattc
    68881 aagatagtga gcgacgaagg taatgtttac aaaataaaga tcgttaatat taatgaatat
    68941 cgagaagcag atcacaaata tttggttgac ttatacatga acgataaata tttgggagaa
    69001 ggattttgtg gagattcact ttttgatgat gagcgaattt tgaaggagga aacagaatga
    69061 tccacgaact aaaaatacta ccagaatatt ttgaagcagt gacgagcgga cgcaaacaat
    69121 tcgagatccg caagaatgat cgtgacttca aagttggtga tcagttaata ctacgtgaat
    69181 ataaaaaata cattaaacat gaattacctg gactaacgag accaacattt agttacactg
    69241 gtgactcata caaagcagag atcacttata ttactgatta catgcagaag tccggatatg
    69301 tagtgttggg gattaaaggg gtgaattaaa tgaaagtata catcttagct atcacagagg
    69361 gcacatggat gttcccagtc ggttccggaa aaatctataa atcaaaaaca gctgcttata
    69421 aagcatttga aaaatacaaa aaagaaaacg gtggcggcac taacgcaaag attctagtgg
    69481 ctgataactg gcatgaagaa ggtgaacgta attgatttac ctgttcattt tcgtggtact
    69541 aactattttt atgctagtaa tcttattcaa aaaaagatga gtaaagacga acgaaaaatt
    69601 ctggccaact tttatttagt attaaaaatc gaacaaaatg tgttttcgga aaggagaatt
    69661 gtatgggaaa aacaaaatca aagattaaga agaaaaaacg acgtttggaa caaaaggcaa
    69721 tccagaatgg aacggctaag aaaaaataaa aaagctaccc ctttcgagat agcagcgcaa
    69781 tactattcta ccataagggg tggcgtttgt gagatttcat tggttaaaag attaccaaga
    69841 actagatgag cagattcttt acttaaagtg gaatcttaat aaaagtaagc ttgaattgaa
    69901 tcgatgggtc tgtggtgatt tagcaaacgt ccgcatcgaa aagaattcga gaacttcttc
    69961 tttagaagag aatatccaaa agatagaaaa tgaattggaa ttgttgatcg agcaaaaaga
    70021 agaaatgtta ttgctgatag atagcttttc tggtatcgat aatcaaattg ttaagatgaa
    70081 atatgttgat caaatgagct tagaagatat tgctgaatct gttgggtata gctcatcgta
    70141 tgtcagacag cgacatgcag aaattagaaa gacattgaac tttttagatg agtatgaaca
    70201 cagacaagct gaccgattga aaaaagaaaa cgaaattgat ttttacaata gcgagaagta
    70261 caaagaacaa ctctctttat tctaaaatta cactgttcac taaatgttcg gtcattgtag
    70321 ctatgtaaac attgttagca gcatgatatt ctattagtgt caaaaaaata tgaaagagcc
    70381 aagatatccc aaccgtttta ttaattggta tctgtggctc ttttattctt ttaattagta
    70441 gttggcataa agttatttcc atttataaat tgatcagcta aatcagcatc ataatcagcc
    70501 gcgataaatt gcgctgctga tttaataaat gcatccatat catgaacatc tttattagta
    70561 tgtctacgaa catagtgcgt ttcatcatta ccaatccaag tagcagcttt ggctaatctt
    70621 tggagtttag gaaaatcatt caaataattt tcaattgttt tacctaataa catttttttt
    70681 attttatctt catcctctga atttttagat attgcataat ctttaattag aaattctaga
    70741 gcttttctat aaccaactcc agcaatttgt tccaattgct cagatttagc ttgtgtggct
    70801 tgagtataaa tatcaacaaa tgtaggagaa actttttcaa tattttctgg taaatctatt
    70861 ttaatcggcg gacggtaata atctttaatt aaaatatttt cagaatatcc ttcatcttca
    70921 ttaaacgtat ttataaattg taaactataa aatttgttgc actcatcatt tatacactgt
    70981 actaatacgc caaagattct atcattatcg aacgcactat atgatgaaac cccaaaatac
    71041 acatacggag tcattatatt tccgcaatgc ggacaactat ttggcaaata aattgtctct
    71101 gtattttgac gatcacgata cttaatatta acttcttgaa gcattaaaac acctcgcatc
    71161 ttttttataa atcataccac aaaatatctg ataggagagt aaacaaatga atgattttca
    71221 tgaagcggta cttagtattg aagtagaatc aagtttggct aaagtttata agaaagcaat
    71281 tgaagcagag aatagtccgt acagagaaaa ttggaatggt aatcatgcac atgtgcaagt
    71341 ggagaatgat gattacagaa ctggaatgaa tacgttagtt atttctttat tgtcacacac
    71401 tctacccaat ctgcaggaaa cgattgaatg gtatgagcga atgggcgcaa aagtaatccg
    71461 tacaaattac aaaggagaga attaaaatgg caatgatcaa aattagaaca tccattagtg
    71521 gaacagagta ttgggattca gaaaagaaaa ggacagtagt tgttccgaaa gatcaagaac
    71581 caaattttga agtaaaagaa gaaaaaggaa ttttgagtga tggcaaatca tttgttgctg
    71641 tcaatggcga actcatagct catagcagtg aaattcttga tagcgatgga aacactgctg
    71701 ctaattttga tggagacgaa gctactaatg atcagtccac tgaagatacg gatgaactgg
    71761 acaatatgac tgcaaaagaa ttgcgtgcat atgctaagaa acatggtatt gatattcctg
    71821 gtgctatccg tgcaaaaggc gatatcataa atcttattcg tgaagtagaa tgaaatactg
    71881 tcagtttgac ggatgcacga acaaaatagc aaagggtatc tactgtactg aacacaagag
    71941 atcaagcaga tcacgcaaga agaagcagca agcaaagtct gtttatcatc atgagaacaa
    72001 accattctat cgaacgcaag catggaaaga tatgcgtcaa tttatttatg aaagagaagg
    72061 tggtcattgt cagcggtgtg gtcagttcat atttggaaag agagcacacg tccatcacat
    72121 tgtaccaatc aaagacaacg aactgcttaa gcttgatcca aacaatctca tgctattatg
    72181 ttcaaaatgt catccaattg ttgaaaacga aacggaagac aaaaaagttt ttccttcgta
    72241 tttcaattga agccccccta ttcattttca aaattttttc gcgtggggag atagggtagc
    72301 ggggagtcac gcgcatcgtt aggtcaaatt tttcaaaaaa caaagggggg tgtatacaaa
    72361 aatgacgact aaagcgcaac gtaaagcgat tattgatgaa aaagtaagtg ctgaaaaagc
    72421 tcgtatctta gaaataatga atttgtctga tttgtacacc atcactcttg atccattaat
    72481 cgaatcatac ttggatattt ttgaaattta ccaacacaaa tatttattgt ggaaggaaaa
    72541 aggatttccg gagacgcaaa aattcacgaa taaatcagga gctactaatc aatcaaaaca
    72601 tccattggca caacaagtag aaacttgggc agataagaag atgaaagctc tagatttatt
    72661 aggattaaca aacaaagcaa aaactggtag actaattgct ggaggatcga ccgcaagaaa
    72721 agatgaagaa attacacgcc cagaagtaaa gccagtagat gaactagcag cgcacagaaa
    72781 taaatggcgt aagaaggcag gtgctgaaaa atgattgaac ctggtgtaaa ttatgctgat
    72841 ttatttgcaa aagaagtaag aaagaaacct aagaagtatc ctaagaccgt tcgtttagca
    72901 atagatcgct ggtatcagtg gaaaaaaaga aaagatattt ggtttgatgt agatcgcgcg
    72961 aatgaaatga tggattgggt agaatcattt attgttcaca caaaaggaga aatggtggga
    73021 aaaccgtttc ttttagaacc ctgggaaaaa tttatttatt cttggattta tggttgggtt
    73081 aaagaaaatg aaaaaggcca aattgtacgc gttactcgtg aggcttatgt ccagattcca
    73141 aaaaagaatg gtaaaacatt gattgctgtc ggttcattag gatatgcaat gtacggagaa
    73201 ggggcgttat cagttgattg ctatgcttgc gcatctgatt ttgctcaagc gcaatatgct
    73261 gccaaacctt ttgcagttac aatcttaaac aatccaatcc tacttgaagg aactaaaata
    73321 tttagggggc caaagggaac tgtttctagt attacttatg actatattca tgaagatatg
    73381 gcttactcaa ataaatttat tgttcaaacc aagaatattg ataatatcga gggatccaat
    73441 ccatattttg tattgaacga tgaattgcat aaacaggaga aaatggaaca gtatgacaat
    73501 tttaagtctg ctcagatatc tttaccacag ccattgatgt ttaatatctc aactgctggg
    73561 aaaggttcgt cgtctgttgg aatgcgtgta tatcgcgaag caaaagaagt gttgaaacgt
    73621 gatgataatg attcaaactt tgttctaatc tatgagccaa ataaaaatta tgattggacg
    73681 gatagaaaag tctgggaaat gtgcaatcct aactggggaa tatcagtcga tttatctgtt
    73741 ttagaatcgg catttaaaac agcgcaacgg tcagctcatt ccaaagctga atttctaacg
    73801 aaacacttgg atgtatttgt gaacggcgcg gataatttct ttgaacagga tcaagtagag
    73861 ccatgtttag ttaccacaca agaacttggt gatttaagtg gcgaaccatg ttatatcggt
    73921 ttagatttat cacgtacacg agatttgacc tgtgtatctt taaacttccc aacatgggat
    73981 gaagatggta aagcggttct taaagtaaag caactttatt ttattccgaa tgaagattta
    74041 gagtttcgag aaaaagaaga taatgttcct tacagtgatt tggctgaaca aggtttcgtt
    74101 gaattttgcg acggaaaaat gattgatcaa gatcagattt tgcagtacat agaggactgc
    74161 atgaatttat atgatattca gcaagtgaat tatgatccag cgatgagtga caaacttgtt
    74221 gagaaattag aaaacttagg attggaatgc gttgaagttg ctcaatatcc taaagtattg
    74281 aatgctcctt ttgacgatgt cgaacggttg ttttatgaga aacgaattca atttgataat
    74341 ccattattcc tttattgcac tttgaacgtt gtagcaatta ctaacatcaa tggacaaaaa
    74401 gcgccaagta aacgtcaatc aaagaaaaag attgatgggt tcgtggcgtt tttgtgtggt
    74461 cataaggaaa cgatgaatca aatgacagat attgattcag atgagttaga tgattaccta
    74521 agttccatct atagataaat agaaaggcgg tgaaaaaaat tgaaattacg tgatcggtta
    74581 tcgaatgcag tctattcttt tatggaaaaa cgtggatata tcgaggatat ttttggacac
    74641 tacacacgtt atggtcaaag atatgtgacg gattcatcta tcatggaatc ttctgatgtt
    74701 tatgaattag ttcaagacat atctaatcag gtggcattgg ccacaccaat tgttattggt
    74761 cccgacggca acgaagtcaa agatcatcac ttactaaata ttttgaagag tcccaatgat
    74821 tatttgacag gattcgaatt taccaaattg gaaacaaata ctttattgat caatggtgag
    74881 acattcccat taacggatag ggatcagctt catttggcgt acggtgtaac aactaaaatc
    74941 aatgaacgac ttcaagaaga atttgaaatg aatggtcaaa aaatacctgg tcaaatgatt
    75001 cgacacatta agaacatcgg aactgattca ttaaaaggtg ctggaataat tgatcttgca
    75061 agaaacactc tagaaggcgt tctgagcgct gaaaaagttt tgacggacaa atatactaaa
    75121 ggcggtttac ttgcgttcat gcttaaacta gacgcccaca tcaatccaaa taatagcgcc
    75181 caaacaaaaa ttgtcaaagc tatattggat caactggaag gaacgcaaaa tgagagtgat
    75241 cattctgtta agatgattcc tttgggaaaa ggatattcca tcgagacatt aaaaagtcct
    75301 gttgatgacg cggcaatttt gaattattta ggtgtttaca aaaaagactt aggaaaattt
    75361 ctaggaatca atgttgatac gtatcaatcg ctgatgaaga cagatattga aaaagcgatg
    75421 atgtatctgc acaacaaagc aatcaaacca atattgaaaa acaagagcga acattacacc
    75481 gctctttttt ttatgcctaa ttctggctat agagtggaat ggaaaattaa tattttggat
    75541 tttgttcctt actcaacaaa aacaaatatt ggctacaaca tcgttcgtac cgggattaca
    75601 agtccagata acgtggcaga aatgcttggt tttcctaaac agaatactcc agaaacacaa
    75661 gctatctata tttcaaatga cttatctagg attggccaga aaaatgcaac agatgattcc
    75721 ttaccaacga atgatcaaga cttgaaagga ggtgatggaa atgaagaaga aggaaattcg
    75781 cacgattgac atcaccaatc tttcaacacg ttccgatgaa gaaactcata cgaggaccat
    75841 tagcggctac gctgctgtat tcaacagtca aacactttta tgggatgact taagcgaagt
    75901 gattgttcct ggtgcattct caaaggcaat tagtaattcg gatgttcgtt gtttgttcaa
    75961 tcacgattgg tccaatgtgc taggacgtac taaaagcgga acccttcgcc ttgaagaaga
    76021 tgaacgtggt ttgaaattcg aagttgattt accggacaca acggtagcaa gggacttagt
    76081 taaatctatg gaacgaggag acatcaacca atgtagtttt ggttttgtgc cgactgaaga
    76141 aacgtgggac tacaattctg aaccaatgct tcgaacaatc catgaagtgg aattatacga
    76201 ggtttctatt gtgcctttgc cagcatacga agatacagaa gctgcattaa gaagtcgtga
    76261 tgaattagaa aaaaacgtcg aagaaagaaa aaaattaatc aaaaaaatta atcaagcgct
    76321 agaagcgtag gaggaaaaat acatggataa agaattattg aaaaaaatga aggcacgtcg
    76381 tgagcaacga ttgactgaat tacgtgaaaa agttgaatca ggagaattac gcgaagcaga
    76441 tttagaagcc gtgaaagaag aaattgacag tgttattgat gaattgaacg gaattaaaga
    76501 cgaattaggc gcagattctg gaactgatga aacagacgac aatacagatg atcaatcgaa
    76561 tagtacggat tcagacgaaa gccgttctgg tgaagacaac gatcaagaag aagattcaga
    76621 cagtgaagat agttcagaaa atcgttctgg aatgattact caacagcaac gagatggatt
    76681 acttggatca attaagaacg gattggaggc acgtgcaaaa atgaccaaga aacaaaaaga
    76741 tcaacaacta cgaaaagcat ttgctaattt tgtagctgga aatatttctg aagcagaagc
    76801 tcgagcttta gggattgaag ctggcaacgg ttcagttact gtcccagaag taattgcatc
    76861 tgaagttatt acttatgctc aagaagaaaa tttacttcgt aaatacggaa cagtggtgcg
    76921 aacatcagga gatgtcaaat atccaattct tgtgaagaaa gcagatgcga atgtaaacaa
    76981 gaaagagcgt tcaactgata ttgctgaaac agctattcag tttgatgaaa ttttgcttaa
    77041 tcctgccgaa ttcgatgctt tggcaacagt aactaaaaaa ttattaaaaa tgtctggtgt
    77101 tccagttgaa gatattgttg tggaagaatt gaaaaaagct tatgtgcgta aagaaatcaa
    77161 ttatatgttc aatggtgatg acgctggaaa tgaaaatcct ggtgcattag ccaaaaaggc
    77221 tgtagcattt aaaaaacctt tagatctaac tgcttcaggt gctgggcaaa aattatatga
    77281 tgcattaatc gaatttaaaa atacaccagt gacagaagtg atgaaaaagg gacgctttat
    77341 tattaatcga gctgctttga ctgccattga aaaaatgaaa acagatgatg gatttccttt
    77401 gttgcggcca ttcacacaag cagaaggtgg aattggttac caattagttg gctatcctgt
    77461 ggattggaca gatgcagcag ataaaaaggg tgaaccagac acgccagttt tatattttgg
    77521 cgatttttct gcatttaaaa ttcaagaagt tattggtgcc ttggaaattc aaaaacttgt
    77581 tgaaaaattc tctggtaaaa atcaaattgg attccaaatt tacaacttgc tagatggtca
    77641 attggtttat tctccatttg aaccggcagt atatcgctac gaaattacaa aaccagttgg
    77701 tggttaagat ggaagagcaa actaaagaat tgtctttaga ggaaaaattc aaatcacata
    77761 ttcattttga agagggcatg gatgattctt tgctctcttt ttatttaaat atggcaaaag
    77821 attatgtcaa aacagcaact ggtggccaac aagaatatct tattttgatg gttgccggca
    77881 ttgcctatga atatagagtt tcagaggatg aactcgacaa agctatgaat gccatgacgc
    77941 catttatcgt gcaaggagcg attcaaaatg ccgaagagac agactaataa tctcagatgg
    78001 aaagccgaat tgctagacat caaaacagga acagacggaa acgatcgtcc aactacaatt
    78061 tacgaattta agcgtctaat attctatgaa gaactcggtg tgacttctca agaaaaatat
    78121 ttatcacagc aagccaagac agacgttgtc agacgaatta aagtcagatg ggataaatcc
    78181 atcacagaga aattaagtgc gctcaaaatt gattctgtaa cgtataacat tactcgcatt
    78241 tatacgaatc ccgatgcaag agaaatggag ttgagtttag cttatgtcga ttagctttga
    78301 tgaattgaaa acagcgctga aatcaacaaa gttagcagtg ttcagagaca aagccagatt
    78361 agggacgatg tatccataca ttgtgtactc aaatgtgagt aacagcaaaa aaatggcatc
    78421 cggtaaagtc tataaaaaat taccttatta ccaagtctct ttttttacac ttggaacaga
    78481 acaggattta gttgttattg aacaagcgct gcaaaatgct ggcattccat attcagattt
    78541 tacaggtata caaggtgatg agaacgacga taccgtaacc aactattaca catatgtgag
    78601 gtgtgtggaa aatgccaagt aataagaatg gtttttctga aatatcggat tatttaggaa
    78661 acctttcaaa agttgatccg aaaaaattat cgttggaatc tttagaagaa gcagctaact
    78721 tttatctaaa gcagttgctt cctaatattc ctaagtcgct cttaaaaaag aaacatatgc
    78781 gcgatcaaat aaaagtagta gttgaaaacg atcaagtgaa agttcaattt gaagagacgg
    78841 ccttttactg gcgctttgcc gaaaatggca caacaaatca acgtgcccaa cattttgcaa
    78901 gtggtacgta tgaacaaaac aaagaaaaaa ttgaagaaat tatgactaga aaaatacttg
    78961 atttatggga agggtgattt taattgggaa aacaagatac tttttatttt gaaggattgg
    79021 acgacatttt aattgcgatg atggcaacgc cagattctgt tggaactgca ccgacttata
    79081 gtgaagtttt acgattgcca attgccacaa aaatcggtgt caaagggaat ggaacagcat
    79141 tagaaaaatg ggcatccagc aaaatgtttc gtcgtgtgtc gcgagaaaca aaacatgaac
    79201 ttgcgttgga tcacgtgggt attccgatag aagtgatgga tgaaatcaaa ggattagttg
    79261 ctaaaagcgg agtaacgttt agcaaaaata ccgcacgaga atttccgtac ttcgcctttg
    79321 gatttattgg aaatattgaa aatggcggta aaaaagcagt ttggtatcct aatacacaac
    79381 tatccaatgt gattgacgaa gagtatgcca ctgcagagga agaaacaaaa attgacgatg
    79441 taactgcaaa tctggtttcc atcggactga aatacaataa tgtgatgtat gcaagttttg
    79501 attcaaatag agacggagct tctctagaat tatttaataa attcattgct caacctgtat
    79561 acgatgaaga acagtggaaa acattggcta aagttggagg tgcgggttaa tggctcggtt
    79621 atctgattat ggaattcacg ttgaagactt aaaaaattct gctgttgtaa ttattcaagg
    79681 cgcagaattc cctatttcat ttactatgca aacgatggaa tttatagcag atgtgtatgg
    79741 tggagattat tcgcaatttg aatctgatat gaacgccatg ctatctaaaa aagaaggaca
    79801 aatttcttct gctaacttat cgcctagtga tctaaaaatc atgcgtgcct tgatttatgc
    79861 catgctgcgt actggtggtt tagaggaaga tccagaaact attttcaaat ttttgggaat
    79921 gagtggagag gtgttgtctg cttatagtac ctgtatggaa atttttgcta gccagacatt
    79981 tcaggtggaa gacctaaaaa aatccaagaa gccacaagac tttcaaaaag cgcaagcaaa
    80041 aagaaagaaa aacaaaaaga atcggaagag ataggaactc cttggagttt ttatatttac
    80101 gttgctctca ctctattgaa ttggagtgag agtttctttt taaagtctac acctaacttg
    80161 tggctcaaat cttatttaca gtggttacaa caaaacaccg attttgaacc acctcaatct
    80221 gtaactatgg ataaatcgcc ttggtggtag aaaggagcgc taagataaat ggctggtaaa
    80281 gaatctgatg tcgttcttaa ttttaaaacg aatggcgaag tcagttattc gaaaacaatc
    80341 aaagaaatca acaaagaaat gaacttagcc gctgccgagt acaaaaacca agtgtctgcg
    80401 atggacaagg atgcaactca aacagaaaaa ttgcgagcgg ctaaacaaaa attagaaaaa
    80461 caattaggat tggctgaaca acgatctcaa atgctgagag aggaatatga aaaatctgtc
    80521 aaagaaaccg gtgaatattc tgctgaatca gaaaaacttt ataaacaatt actcaattct
    80581 gaaaccggag aaaataaact tcgtacagca ttagaacaga cgaacgatgc acttaaagaa
    80641 caaggtgacg tttctgttga tacagcaaaa aaactccaga aaatcgaaga aacaggtgag
    80701 aaagtaaaag gcgttggtga aaaaatgtct gttggagtaa ccgcgcctat tgtagcggca
    80761 ggagcagcag gacttgcagc atttggtgaa gttgacgagg cacttgatac catcattaca
    80821 aaaaccggag caacaggtga tcaagctgat agactttcac agtctttcaa aaacgttggt
    80881 tcaaatactc atttaccttt acaaacggtt ggggaagcta ttggtgaggt aaatacacaa
    80941 tttggattca tggataaaaa actggaagat tcaaccaatt atctcctaca gtacgctgaa
    81001 atcaatgata cagatgtttc gcaatcagca atatctgctc gacaagctat tgatgcttat
    81061 ggactagaat atgatgattt gaattctgtc cttgatgtaa caacgaaaac atcgcagaat
    81121 actggtcaat ctgtagacga cttgatgcaa aaagcaattg atggcgcacc acaaattaaa
    81181 caattagggt tgagctttgg tgaaggggtc actttacttg gacaatttga gcaatctggt
    81241 gttgattcaa gcgcagcttt aagtagttta tctaaagcaa cagtggctta tgcgaaagac
    81301 ggaaaatctt taagtcaagg actagaagaa ctacaagaca aggtaaaaaa tgcaggttct
    81361 gaaacagaag ccatcaatgc agcagcagaa gtattcggga ctaaaggcgg tcctagaatg
    81421 gccgatgcaa ttcgtagagg tactttgaac ctggaagatt tagcaaaaac tgctggagaa
    81481 agtgggggag ctgtaggaga cacattcgat gctactctcg acccaattga tcaagccgat
    81541 caagctatga acaatgcaaa attagcaatg gctgacgtag gtgaagcagt ccaagtaagc
    81601 cttttgcctt tttttgaaaa agcaacttcc ttattacagg aattctctaa atggtggggg
    81661 tctctagatc aagatacaaa gaattggatc ataacaattg ctggtatagc ggcagcagtt
    81721 ggaccagtac taatcgttct tggttcactt atgggatctg ttacaaaaat cgttggggaa
    81781 gttaaaagtt ttataggagt ttggcaagga cttgctggtt tatttggaat gtcgggaggc
    81841 tggtttgcat tagcagttat agctattggc gcattagtta ctggactaat ttgggcatat
    81901 aataacgtta aatggtttca tgatggagtg aattctttct tcaaaggtgt ttcagatgta
    81961 gctgttgaaa tatttaattt tttaagtggt tattttggtg gatttttcga tggtgttata
    82021 gcaaatttca ataattttta taatgctgga aaacgaattt tcagtggttt tctagatttt
    82081 atcactggag tatttacagg gaattggtca aaagcatggc aaggtctagt tgatattttt
    82141 ggaggtattt tcgatggtat tgttgctgta gggaaagctc ctattaatgc catgattgga
    82201 ttgatcaatg gatttattgg tggattgaat aatataaaga taccaaaatg ggttcctggt
    82261 gtaggtggaa aatcattttc tatttcaaaa ctgccttatt tagcacaagg cggtcatcta
    82321 atcaatggac aagcgattgt tggtgaagct ggacctgagt tactgactgc caagaatggt
    82381 aaaaccacag ttactccatt atcagacgaa gaaaaacgca aagggatcag tggaagagtt
    82441 tctggaggta gcattgaaca gcatatacac attggcaaag tcgatgcaaa caatccatct
    82501 gagttagatc gtatgaatcg taaatttgct aaagcaaaca aacaggctat tcgtgatttg
    82561 ggaggtgttc ctatttgagt cgacaattta tgaatccaga tgaaccaaat tttatttgga
    82621 aaaatcggaa tgcagtaatt gatatgaatt gcatcattga ggcagagctt ccagatatta
    82681 tgccgaacaa gcgatacgaa acttacacga ttcagggccg aagcggagaa ttgacggaga
    82741 cgtttgatga ctatgaacct tttgatttgg aaatagaagg gatcactatt ccacattcga
    82801 aactgagaga agtcaaacga tggctcactg gtaaaagcca attaatcaca cataatgatc
    82861 cagacaagta tctagaggct atctgcagca tggataaaga agtccctttc gaaaacgagt
    82921 ggggcttctt ttatacattc gatgttactt ttcgttgtca gccactcaaa agaaaaatcg
    82981 gtgaagcacc taaaattttt cattctagtg ttatggatat ttttgatcat ggtgacgaaa
    83041 ttgcacatcc ctatctggaa atagaatcga acggaggaga tataacgatc gctgtcggtg
    83101 ataaaagcct aacaatactt aatacgttag ctgcaacaat cgtggttgat actcagcttg
    83161 gaaaagcaat acaagaaggt ttgaatttat ttacgcgtgg tgattggcca gtattgcagc
    83221 ctgaatggaa tcaggtaaaa atatccggaa aatttaaaga agtgcggttt tggaatagga
    83281 gtgtgtatct gtgacgcaag aatttattta tgcttataaa aaaatgccag atgatttgag
    83341 cgtgaacgga gcgtcgttag ttgattggga agatttgcca gaaatcaatc gtgtgctgaa
    83401 tggccaatat cgtttttatg gtaactattc aagaagcgga cagtatcgct cttatttaaa
    83461 aaaaggaaat tttataaaag cgaaggtacc agatggatca tggcaatatt ttgaaattta
    83521 taatgtcaaa aagaatttga cctccgtttc tgtaacagct cggcatattg gttttatggc
    83581 caataagaac tttattgtca agtcgtttac ggataacggc aatgggtctc agatcatgac
    83641 caatcttaaa aacagtttgg catttgatca aaaatttaac tatctttcga atgtagggac
    83701 aacgcaccaa tttacagcaa gacaagtcgc gccagttgaa gcaatcattg gttcaaataa
    83761 cggtaatcaa aatttgactg gcgtgactag cgcggaactt gatatggata actatgattt
    83821 gaaactggta aaacagattg gatcagataa tggttttcgg attgattttg gcatcaattt
    83881 agaagcaatc gaagaagaaa ttgatgaaga atcaattgtc aatagtttgt atttggttgg
    83941 cggtgttcct gataacgatt atgatgaaga caaagaacct atcgaatatg gttatttaga
    84001 aattgatgga gtaaccaacg agaatcgacg tattgccaaa cgtgaaaacg gagattgtaa
    84061 aacagttgat gaattgatca aatggggcaa aaccttattt gacaatgatc gtatccatga
    84121 gccaaaagct actcatacag tcagtatggt ggcgttggaa cacacactcg aatacggtga
    84181 catgtatcaa gagctagcgt ctttacactt tggtgatgtc gctcatgtta gggcgaaaga
    84241 gctagatatc gagataaaag agcgtatggt cgaatacact tatttcccaa cgcttgggaa
    84301 atataaggat attgttttag gtaatgattt atcactgtac acttcggcag taaatactca
    84361 agcacaagaa ttgaaaaaga aaatcgacaa tcgaacagaa acgttagttc aaaatgtgtt
    84421 gaatgcgacg gcatggatca ctggtaattc tggtgggcat gtcgtttttc gtccagaaaa
    84481 agctccatca gagattctta tcatggatac tccaaatgtg gcgaatgcaa agcgagtgtg
    84541 gcgttggaat ttaaatggct taggttattc agacaacgga gtaaatggcc cgttcggtat
    84601 tgctatcaca tcaaaaggag aaattgttgc tgacttcatc aaagtaggaa caataaatgc
    84661 agaagtattc gaaacttcct ttaatgctta tggtgatgtg ttaaaacttg taaaaggcac
    84721 gcttcaaatt tggaatgaaa acaaaaaaat catggagcta accaaaaaag gtatggaatt
    84781 ctggaataga aaagaatcca ttggaacgat cggaacaaca gattcagcag gaaatccatt
    84841 tccaaatgct gtaacaccta cacctcttga ggaaaattct ttggtaatac gtacaaatgg
    84901 cgatggaaaa tacattttaa tttctccaac tgcagaaaaa ggatttgtgt tattaggaaa
    84961 cggaaaagca tattatttcg gtgatttaga tattcaggga aaacttactg ttagaggtaa
    85021 agaagtgata ccaggacaaa atggcggtcc atctggcgga ggagaaacac ctggtgggta
    85081 tcctgatgaa ttaaaaacag atgcagaaaa gagagcttgg agaatatacg atattttgtg
    85141 taataacgga tttacgaaac aatctgcatg tggaatattg gggaacattc aacaagaaac
    85201 aggaggaact tttgatcctg atactgttca aataggtgga ccagcatacg gattagttca
    85261 gtgggatggt tcttcatatc ctcttgttgg tccagcaaca tgggatggaa aagtttatgt
    85321 tcaaaactta tttaatgctg caggtattaa agaaccaata acgagcttag atgcacaagt
    85381 tcgattgctt atttggacat ttacaaatgg acaatggatg g
//
LOCUS       DAZKKZ010000002        84062 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.002, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000002 DAZKKZ010000000
VERSION     DAZKKZ010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 84062)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 84062)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..84062
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.002"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..355
                     /locus_tag="ACG8LA_000111"
     CDS             <1..355
                     /locus_tag="ACG8LA_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202453.1"
                     /translation="DLKIGETYQADGVELTFKNIEVTEKRNEFAQHDRVLQVTYTLKN
                     DTEKPIRPQQWSIENKDGEELYEYAMILDNPEYIESDKEETVNYYYELPIERQDYQIV
                     VRRANGYFVGLPFTL"
     gene            432..746
                     /locus_tag="ACG8LA_000112"
     CDS             432..746
                     /locus_tag="ACG8LA_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202454.1"
                     /translation="MAEENKVVPFETLVINKEEFEQLFLDFFIQYDRIYDFSSSLDLF
                     ELEAEIIENSREKNGKIIISVEKFNELFSETFEIDPDYYQPQEVFREFRNQIIRSSNI
                     EN"
     gene            994..1923
                     /locus_tag="ACG8LA_000113"
     CDS             994..1923
                     /locus_tag="ACG8LA_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202455.1"
                     /translation="MRSDSRFFVSNLQDDELIRQIDSLLETITESDKRIFLNYVELTR
                     HIIELDKLFNVFRYNLTNLLKHFTIFTNDLIESTGEKLTEDQYYYQINALTINLISSA
                     KTLTESIEVCMKNFLAEKDFKSFKNKILSKPYDEHFSYRFLLHMRNYSQHGHLPVNIH
                     QQRVYFDLDEILAMPHFDFNGQLKKELDVLRKDIYNQFRDSPRISYVYTVAKFNLVIT
                     EIYFNYLKEIKPILIKLNDEKNELLLNTKFQLINSDGSSSDMLFYEFDGENYHCFNRK
                     DNSISMYADIKREVKKILKVEEQYYKEIEKRNQ"
     gene            2092..3417
                     /locus_tag="ACG8LA_000114"
     CDS             2092..3417
                     /locus_tag="ACG8LA_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202456.1"
                     /translation="MENIEETFLKVLSPYISDSILRFQEQEKNYKFGFDIKNYNDSLH
                     VVFQYNKTGKIGIKEVHIFQIFLAKVNIEASKSKLNYTTLLDTNALFFSKKLLPYLHS
                     YEWALRKLIYLLAPAYFSDNWAEESIPNEIISSIKRKQIQAIGKFDSKNLLQWIDLYD
                     FEEYLFGENYILVTQENEENIVRYKEISQDQLLKLFQDNSHTISDSYSLWSEVFSKYM
                     DVKLEEIQTDMSLIREGRNIVSHNKEIEMALYQKLIKKLKRYTNQLEKAFQKILAGDI
                     AGEDLSDMSDDFEGYIGNYFSNIDLAGVTKLSESLSAMKVLNTDSMKKSMESIGQTLS
                     VQQEIMQNFDTEGIRRATEGINQSLQSIKILNTDSMKRSIESIGQTLSALSAQRAIMQ
                     NFDTKGIRSATEGINQSLQSMKIVNTDSMKRSMESIGKISSTNQVLKSE"
     gene            3517..4335
                     /locus_tag="ACG8LA_000115"
     CDS             3517..4335
                     /locus_tag="ACG8LA_000115"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202457.1"
                     /translation="MVQGLFGGGTSYEGQSISDIKEDVNNWKIYTENVKSQIVEKKEA
                     LIKNGFWNKIPWNFQQTINESIFCLGTFLSDFQIVESAFEENFISEREIKLLRKIGKN
                     SVQFNHSYGKYFKEEYEWREYGNPEFEIVESIYQHGRDFFVTLQDASNAAGRLEDYMS
                     NNSIYNKVNIFGNSYNTNIQQGHNNNMIVSIDDMSELLSKLDLLLENLNDSLPEEEVE
                     EAQEYIETIKDEAIKEKPKKTMLRFAVDSLKKLKWSTEFLASVATIAQLVAPLL"
     gene            complement(4774..5919)
                     /locus_tag="ACG8LA_000116"
     CDS             complement(4774..5919)
                     /locus_tag="ACG8LA_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFQ0202458.1"
                     /translation="MATFKQYETKKGKFWLYEAYLGMNKMTGKPDKVRRRGYKTKKEA
                     QLALSRLQVDYDKNGIKKANNETFKEVYDLWLETYKTTVREATFMKTEIKFRKWILPK
                     YGNLRVNEVTVKKAQQIVNSWAETTDQYKVLHSTSKRIFSYAINLGIIETNPLDNVLM
                     PKRTTTKHKEKVKVYSKEQLITLFDYLNSKPETYRNDFDKTLLRFLFYSGVRISEALA
                     LNWSDIDFQENTVTINKTLSQSKNGYKISDPKTDCSAGVLPLDERTISILKKWQINQR
                     KYMLTLGVTDPTMIFCGIYKELITHHAIYARLITICEKAMVPFLGVHVARHTHASMLL
                     DAGATMVEVQTRLRHTKISQTIDCYGHLAKETKEKTVEKLVQHLNID"
     gene            complement(5980..6627)
                     /locus_tag="ACG8LA_000117"
     CDS             complement(5980..6627)
                     /locus_tag="ACG8LA_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFQ0202459.1"
                     /translation="MNGGENVARKKYPEAVETGQRIRLARIEKGLSMEQLGGKLSPPA
                     SKGAVSNWENGYNLPNNTRLKQLSKVLDVSTTYLLNGSYTLRDMHMMPEIKRNVLEKQ
                     LKKTIEKNNSIIDSNLSNAINNIEEDNLTVSQKIYLTNAIKYLKTGSRIEFPDGSTPI
                     AYLAALLNTLLRYDSLINDSEKNTDEKKEYQEFYENDLLKEFTALVTELNKHYSK"
     gene            6821..7114
                     /locus_tag="ACG8LA_000118"
     CDS             6821..7114
                     /locus_tag="ACG8LA_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202460.1"
                     /translation="MELKIDKLTLDDPAFKIIDDRVVQQVEQTQGTLLSLLEKKYQFP
                     KYMNKAQAAKYMNVSYNTMMQKYVPNGLKLIIVDGVVRISQDECDRFMEEYQK"
     gene            7158..7469
                     /locus_tag="ACG8LA_000119"
     CDS             7158..7469
                     /locus_tag="ACG8LA_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202461.1"
                     /translation="MESTQNKAIEKVLSTILTEDTAAELANLEGKALEETFECLYEQM
                     DYQKLLPQEPTVSGVLRGLNDLVQAEFKERLSIEEYQEILYQQVELLASLLGLELEDV
                     E"
     gene            7466..8090
                     /locus_tag="ACG8LA_000120"
                     /pseudo
     CDS             7466..8090
                     /locus_tag="ACG8LA_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350005.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage repressor protein"
     gene            8231..8389
                     /locus_tag="ACG8LA_000121"
     CDS             8231..8389
                     /locus_tag="ACG8LA_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202462.1"
                     /translation="MKRNLIIGSILIGGIFGLLPLIAKIAIFAGLALYLFTAYDEYDY
                     QLRTGGHK"
     gene            8390..8752
                     /locus_tag="ACG8LA_000122"
     CDS             8390..8752
                     /locus_tag="ACG8LA_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202463.1"
                     /translation="MYKTKLLNQLDSLELEEINQGIAELENNIGKTYFGNSFNEKLTV
                     LYVLKKHAEHKIICREINELKNQILTAWLNITDMQEARVKTFNTWVKYQNQLKGAEFV
                     RDGLKYELEQLKLMEVSE"
     gene            8789..9637
                     /locus_tag="ACG8LA_000123"
     CDS             8789..9637
                     /locus_tag="ACG8LA_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DNA primase/polymerase"
                     /protein_id="HFQ0202464.1"
                     /translation="MANNYQAATELQKSGWSIYPLSPGTKIPIKGSSGWNDATNDSNQ
                     INEWWTEDATRNIGLMLEDHQMVVVDLDQHSETRNGVENYKKLASMYDPFPSTYTEIT
                     PGKGIHFFFKIPDGVIIQQETGAFADIFGRDDKGKSLSGIDIITKGVPIAPTMIISRS
                     VGRAYEPIENVSLNNIAPAPDWLVNLLLKKPQEIKTQYRPVAKTGTAKKLDMIVQGAG
                     EGSRNDHLTKLCGWLLWHGVDNQTLAELIYTANAYNEPPLKDKEVNQIIRSMIKKDLR
                     GKAHGS"
     gene            9627..11102
                     /locus_tag="ACG8LA_000124"
     CDS             9627..11102
                     /locus_tag="ACG8LA_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VapE domain-containing protein"
                     /protein_id="HFQ0202465.1"
                     /translation="MAHKHKLDSILDFPEASEREDNIIELKTWMSRLRCNKDDQIKSN
                     SVVNAELILTNDSNLAGTIAYNEFSGYIHLLKDSPWINRTAGEWEDSFEDALTAYIEE
                     NYNVVFDDNKIHKAVVNVARKNVFNPVKERIEKVKWDQQPRLETLFIDLLGVDDNLYT
                     REVTKRWIVGSVARIYKPGIKFEIVPVLDGPQGIGKSTVPALLYTDDFFTDSLDSLGE
                     KKDDYMQLQGNVIIELGELSSMNKTKIEQIKNFISAKIDKIRPPYGRNVIAWARQCVF
                     IGTSNDGQYLKDDTGNRRFYPLPCKNKPKMNPFKTKDEYFLQVLAEAKVLFDKGQRIY
                     FSPDEDKEVLEIAKDYQEDAKMENPIKEAITKYLEMEIPYKWEEAPAWARRSYYQNYP
                     DSKCNEKNLQHFYNGATMQQEFYLVDSVLTADILEAVFDKQAKDLLNGRSDAETKKIA
                     LIISSIPGWERKQLPKRNKRRGFYNKSNAYENKNRAGKYKK"
     gene            11368..11775
                     /locus_tag="ACG8LA_000125"
     CDS             11368..11775
                     /locus_tag="ACG8LA_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3206 domain-containing protein"
                     /protein_id="HFQ0202466.1"
                     /translation="MLNIISTNKAPNFQYTDEMDRFLMNTLAFSVGLVTEDYSTFDPE
                     VLKIMEEEPDWLQESVAWCQSLVVGSLVDSGNYDDTGELMDEFNCLLNLYDRARQREL
                     TSNEDNLFLNIHDKFLALLLTDDELITNLLEVE"
     gene            11778..11993
                     /locus_tag="ACG8LA_000126"
     CDS             11778..11993
                     /locus_tag="ACG8LA_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202467.1"
                     /translation="MHMESIRYFDGEKHIEYSNTQEDVDFISFEEDKITKVNFKDGTC
                     LKIVSPYIEYKSKWEQDDSDERDRFGW"
     gene            11997..12377
                     /locus_tag="ACG8LA_000127"
     CDS             11997..12377
                     /locus_tag="ACG8LA_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HFQ0202468.1"
                     /translation="MAVKKQCNHAGCKTLIDYRQKYCGKHKAKQTAIKREERKQSEGK
                     YFQFYQSRTWRKASYLYRLNHPVCEDCLEEGLIRKADVVDHKIELKDDWNRRLDETNF
                     RSLCHAHHNSKTANERQRREKSTL"
     gene            12511..12666
                     /locus_tag="ACG8LA_000128"
     CDS             12511..12666
                     /locus_tag="ACG8LA_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010780558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2292 domain-containing protein"
                     /protein_id="HFQ0202469.1"
                     /translation="MKVGDLLKNTIVITDKTGKQRTIELPHFGQVTIQMQNGKIIYID
                     KLDKEKF"
     gene            12735..13208
                     /locus_tag="ACG8LA_000129"
     CDS             12735..13208
                     /locus_tag="ACG8LA_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase small subunit P27 family"
                     /protein_id="HFQ0202470.1"
                     /translation="MGHPKILHDTKGNISSEEKAIRVDAREELFKQQPLINITPPDWM
                     AASARSEWNRIVPTLKKDYPLSEADYGSLVAYCLAFARMKTAEAEIRKSGTFITCENG
                     VKKANPAVRVQSQAMSDLKKQATSLGMTLESRSKLALNKVKNDEPEDPFKELMNS"
     gene            13205..14899
                     /locus_tag="ACG8LA_000130"
     CDS             13205..14899
                     /locus_tag="ACG8LA_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="terminase TerL endonuclease subunit"
                     /protein_id="HFQ0202471.1"
                     /translation="MNDYIEKVLSGKLIAPKKIIQACERHISDLERSKSDSFPYVFDE
                     EQATKAIKFIELLPSTDGKAIKMLGFQKFILGSLYGWRTKEGNYRRFNRAFTSMSRKN
                     GKTYIASGMAANALIMEQEPAEARQVLFVSNALKQAKLGYDMLSNSLRNVVKSSKFLR
                     PQLKIMNSKIQHLPSNSFAMALASETSTLDGFAPTTAILDEWHEAKTRKTYNVIKSGM
                     TQQKNGLLCVISTAGLDLNVPMYEEYLLLDRVLKGEEQADRYFIAIWELDDPEEIHDQ
                     EKWIKANPIFESEEIKKVMIPTIQDDVNLALKQNNLNSVLVKNFNLWRQASEDSYMIA
                     EDWQATEVEPQDITGKPVYIGVDLSKTDDLTSVSWIVPLDNGELYCDSHSFVATKYGL
                     QDKEKRDGLPYRELEKAGECSITQLESGIVDYDQVFQFIQDLIQENDLECMGICYDPY
                     NANSLISKAEKANYPMLEVRQGTITLNVPTRTFREQVYEGNVIHNKNTILTHAVNNAI
                     LKTDNNGIQINKSKNSNKIDPIAALINAYVFAMDYFTTTEGAKADNEFYTSEEFSF"
     gene            14865..15050
                     /locus_tag="ACG8LA_000131"
     CDS             14865..15050
                     /locus_tag="ACG8LA_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202472.1"
                     /translation="MNFIQVKNFLSNYIHTVLLLLGLVCVLVAITLLTNVYYGLLALG
                     IVLIGVAVMLNTEQKGG"
     gene            15054..16229
                     /locus_tag="ACG8LA_000132"
     CDS             15054..16229
                     /locus_tag="ACG8LA_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HFQ0202473.1"
                     /translation="MAFFKARQNTTGDPFLQHVVSIQSDDYTTSFTSVRALRNSDVFA
                     AVRIIASDIASSPIQLVKNNMPQADNELVKLLNEKPNSEMDGWHLKFALAVNMLLNGN
                     SFAEIKRNGEKVEEIHLLPNSSVTVTQLDNGTLSYQIGDKKRRVKSSDILHFKYFTQD
                     GLTGLPPLYALRDELKIQQAGNRTLHNFFTRGVSGSGILKVHKSDLDGSAKNAIREKF
                     EEANGSSSGDNALRTIILDETMDYKTLEINTDVLKLINSNDWNTKQIAKAFGVPIERL
                     GVENEHSSTVQSNLQYIQSTLIHYFNVFVSELDTKLETNIRFNSDQLLETDPETKVKN
                     VLDQVKGSLLTINEGRSKMGLPPMDGGDRLLASLNFTYLDTLEKYQLKEQEGVTPVE"
     gene            16222..17745
                     /locus_tag="ACG8LA_000133"
     CDS             16222..17745
                     /locus_tag="ACG8LA_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HFQ0202474.1"
                     /translation="MNNEEEKEKRLTEEAELTADSPKVEKENEKQPTDGKTISGYALK
                     FGQPSKDLGGFVEVITPEALKEVDLSNVFLLYGHDYSKPLASVKAGTLKLNVDDTGLH
                     FEAELTDTTYSNDVYENISKGVVDSMSFGFVLGLDSFDKKEDGTIERSIDKIKALNEI
                     SVVTVPAYDSSNVQVNKRSYESFMSNNQAKQTNNSLESTSKAQKESNNMEKTLIDNEK
                     TELRGYEEYIRSQGEVRDGVTTVNAAAVVPEEVIGEVFDLKRSNYNLAQYATVKTVSN
                     GQGKYPVATNQQAVLATKAELAEIGDIDAEMFTSVDYKVETRAGKIALSNEVVEDSAV
                     NIVQEVKDQLAKLVENTDNKHIMDLLKTFTKKTAATLDDLKQLYNVALDPALNKMVIL
                     NQSGYYHLDTLKDSDGRYILQPDVTAPSGKSLFGMPVVLIADTLFANPKAGTFPMIMG
                     DIAQSIFVARRNQVTTQWEKFDYYSQGLAVIVRNDYKKIDQNASVYIEFTPVVTPKV"
     gene            17801..18085
                     /locus_tag="ACG8LA_000134"
     CDS             17801..18085
                     /locus_tag="ACG8LA_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="head-tail connector protein"
                     /protein_id="HFQ0202475.1"
                     /translation="MVILDSIKKSMRIDHTIDDDFIQQLIDTAGEYIKSAIDSSATDK
                     DMDNYQQFDLAVSLLTQHWYLNRQEASSERIPVTVQALVQQMRGAYYANH"
     gene            18072..18407
                     /locus_tag="ACG8LA_000135"
     CDS             18072..18407
                     /locus_tag="ACG8LA_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HFQ0202476.1"
                     /translation="MPIIKNVNELTERVKFKKTKRVKDEDGQMVDSEETVFECWANVR
                     SQMLKDVLASVGTILEGTLTFIIRYDQDYELTNDMKVAWKNKSYKIISINEGTAFKDY
                     TTIIAKQIS"
     gene            18702..19328
                     /locus_tag="ACG8LA_000136"
     CDS             18702..19328
                     /locus_tag="ACG8LA_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202477.1"
                     /translation="MDKAEFTNFYWKYYLHLENEFINTTDFVMLDENNFKTFSIEYQK
                     LLLAIGSECEIIFKELCGFDSSSNKSITDFKAVIKSSELMCLDNGVRVMNSLTLTSLK
                     PFGDGWPEDTPDWWKIYNRVKHGRSSNYKEANLENVLYALASLYLLEEYLHKKVILEG
                     EVDFISPESNLFTLSWERKHSSMQKVTFEKVDSNYVAPLIDFKEQEEI"
     gene            20070..20906
                     /locus_tag="ACG8LA_000137"
     CDS             20070..20906
                     /locus_tag="ACG8LA_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HFQ0202478.1"
                     /translation="MIGLIYFVVIVLANTVGAISGMGGGVLIKPILDLIGAHSVAGIS
                     FYSTVAVFTMSIVSTVRQVSSGKSLNWQIVGWVSSGAVVGGVVGNIVFEVFLQLFENE
                     KHVQLIQIFLTVLTLVFAFFYTKHHQPKFHLTSWTWYLICGGVLGFLASFLGIGGGPV
                     NVSLLMLMFALPIKEATLYSLSTIFFSQLAKLVTIALTSSFMRFDLSMLFYVIPAAVI
                     GGLWGARFSRVLSPKKVTFIFQVIVLVVLLVNCYNAFVILQTLGESRLTQVKITETYC
                     SK"
     gene            20971..21405
                     /locus_tag="ACG8LA_000138"
     CDS             20971..21405
                     /locus_tag="ACG8LA_000138"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFQ0202479.1"
                     /translation="MLREMRLEDAEALREINADQLGYDIPLTVTVRQMKKLLKEPEKN
                     FFLVYEDPTSKKAAGYVQAESYESIFSDPMFNIMALAVSKYAEKRGIGKALMTGVEEE
                     AKKRGITTIRLNSAEYRVEAHQFYEHIGYHSDKMQKRFLKIL"
     gene            complement(21473..22795)
                     /locus_tag="ACG8LA_000139"
     CDS             complement(21473..22795)
                     /locus_tag="ACG8LA_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxycarboxylate transporter family protein"
                     /protein_id="HFQ0202480.1"
                     /translation="MAQKTTTATAVEEKKKEGFWSTKITGVSLPLYLIMVLVLIIAMA
                     LGKLPTNMIGPIAVLVIFGNLFHFIGTKIPIVKSYLGGGSVFAIFASAAIATFGILPE
                     YVVKSTENFVSNMGFLDFYIAALITGSILGMNRNLLMKASVRFIPVALISMVVSFFAV
                     GLVGMLIGNGFANSVLYISLPAMAGGVGAGAVPLSTIYANVLGTDASSIISRLIPATA
                     MTNVLAIIGAALVARAGQSMPKFNGNGKLMEKGDLGDGKPRTVKPSIPQLGVGLMVSL
                     TFFILGQIGNYFVPKVHAYAFMIIIVVICKIANLLPEYYEDAAIMFNNLIVKNLTAAV
                     LAGIGIALLNLNVLASALTWQFVVLCLTSVIAISVVSGFVGRLFGLYPIESTITAGLC
                     NNSMGGTGNVAVLSAANRMELIAFAQMGNRLGGAIVLIISGFLMQLLS"
     gene            complement(22949..24589)
                     /locus_tag="ACG8LA_000140"
     CDS             complement(22949..24589)
                     /locus_tag="ACG8LA_000140"
                     /EC_number="4.1.1.101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043883 - malolactic enzyme activity
                     [Evidence IEA];
                     GO_process: GO:0043464 - malolactic fermentation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="malolactic enzyme"
                     /protein_id="HFQ0202481.1"
                     /translation="MLTGLNLLNNPFLNKGTAFTKEERAKYGITGMLPSTVQTLEQQS
                     VQAYGQYLSKQTDLEKRIFLMNLFNTNRTLFYKLMGEHLVEFMPVVYDPVVADSIEQY
                     NEIFLKPQDAAFLSIDEPENIKASLKNAADGRDIRLIVVTDAEGILGMGDWGVNGVDI
                     AIGKLMVYTAAAGINPAQVLPVSIDAGTNNEELLNNPLYLGNRHARVEGETYYEFIDQ
                     FVQSATELFPELLLHWEDFGRGNAAAILEKYEDQITTFNDDIQGTGIVVLAGVLGGLN
                     ISGEQLKDQIILTFGAGTAGVGIANILLDEMIRQGVPEEEARQHFYQVDKQGLLFEDT
                     EGLTPGQIPFARKRSDFTNADELTNLEAVVKAIHPTIMIGTSTQPGAFTEEIVKEMAA
                     HTPRPIIMPLSNPTKLAEAKAKDLIEWTDGKALVGTGIPAADVEYNGVTYQIGQANNA
                     LMYPGLGLGLIASTATRVNAEIISQASRALGGIVDVTKPGAAILPPVAKITEFSQTIA
                     ETVAKSVVAQNLNREEITDIKEAVESAKWVPEYKSLED"
     gene            24919..25389
                     /locus_tag="ACG8LA_000141"
     CDS             24919..25389
                     /locus_tag="ACG8LA_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4809 family protein"
                     /protein_id="HFQ0202482.1"
                     /translation="MKEVQLIRKSELSEGGCNACGVVEATSYTLKLDSNQAIISELTV
                     GGLVDSLALAEGFTGEDIYEMFSEVRQLKKGEKCIEVHHESPNVRFKRGDNEMIFKNH
                     VSDHTELYEIVNQILSGIFELGPYEFKEENGNPKLNEEWQETIETQRNNPHLFQ"
     gene            26018..27121
                     /locus_tag="ACG8LA_000142"
     CDS             26018..27121
                     /locus_tag="ACG8LA_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HFQ0202483.1"
                     /translation="MEKTYQAGTNEGIVDFINMEDLEIAASQVIPAGGYGYISSGAGD
                     LFTYQENERAFNHRLIIPHVLRDVELPDTTTHFDEEMLTAPIIMAPVAAHGLAHVKAE
                     KASAKGVADFGTIYTASSYASCTLEEIREAGGEKAPQWFQFYMSKDNGINLDILEVAK
                     RNGAKAIVLTADATVGGNRETDRRNGFTFPLPMPIVQAYQSGVGQTMDAVYKSSKQKL
                     SPKDVEFIAAHSDLPVYVKGVQSEEDVYRSLESGAGGIWVSNHGGRQLDGGPAAFDSL
                     QYVAEAVDKRVPIVFDSGVRRGQHVFKAIASGADLVAIGRPVIYGLSLGGSTGVHQVF
                     DFFKTELEMVMQLAGTQTVEDIKKIKLRENRFI"
     gene            27405..28085
                     /locus_tag="ACG8LA_000143"
     CDS             27405..28085
                     /locus_tag="ACG8LA_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HFQ0202484.1"
                     /translation="MKKNMIGTLLLSTLLLGGLATPAFAEGQATSKGDITFTEPTNTV
                     EPLNPTDPSKPVEPADPENPATGQTGSLTLDVVPELPFGTHEIESGTKTYQVDASKND
                     TPYLQVSDRRGVGADGQAQGWNVTVSVSDFVNGSQVLQGAELDFGTSTVKSTSDNEST
                     GPTSQTVTGLSKASAATPIFTAAKDQGLGTWLSVYDPANITLKVPKAAAGTFTADLTW
                     NLVAGPVA"
     gene            28175..29209
                     /locus_tag="ACG8LA_000144"
     CDS             28175..29209
                     /locus_tag="ACG8LA_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HFQ0202485.1"
                     /translation="MNQSKRLFVSFFSILSLFFIFPSISQAKDSAGDFGIKPVFPENQ
                     IDKAIGYFDLLVAPEQNQTLEVIISNSSDEERTFEVSVNPAVTSDGGTIDYSQKNPTL
                     DETLPFDVRDVLLIAKKEINVSAHAETTIPIEVKIPAKSFKGRVLAGIHVSPKEEAET
                     ENATEGAQIKNRIAYNLAVVLQESQETIEPDLKLLSGDLDEVNAKPTVQLRFQNPQPR
                     IISNLIFTSKIFYENQLYIENTSNEFLVAPNSNFHLNLDLAGDKAKAGDYRAEIIAKS
                     GDSNEWRFTQNFTIKKEKAQKVNENSVFAVQEQSFPWLYAGLVAAVLVLWLILLFLWV
                     HKKKKKGETT"
     gene            29223..29558
                     /locus_tag="ACG8LA_000145"
     CDS             29223..29558
                     /locus_tag="ACG8LA_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202486.1"
                     /translation="MKTSILLGGIIASLLFFSWQEPVQADTKSSGTITFYDLSPVPHP
                     SGSVNGASKQQTQLPIYKESNQHGVFPETNEEKIRFLYLIIGIELWLLAWLLLWRRKE
                     KEDEHVATK"
     gene            29542..32022
                     /locus_tag="ACG8LA_000146"
                     /pseudo
     CDS             29542..32022
                     /locus_tag="ACG8LA_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326300.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            32078..33637
                     /locus_tag="ACG8LA_000147"
     CDS             32078..33637
                     /locus_tag="ACG8LA_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0202487.1"
                     /translation="MRRKLLLLKSEMLGGVDLELFSLLEKNEQRQIKLFQLLLEEKGE
                     ISVNNVLTRLSVDRATLKEDLFYLQANLENIKQLEIVIQEGNILLIRHGNIAAVDVYY
                     HCYLRYSTKYQILLYLLENGSFDRQKLVMELNISSATLSRRVKELNDSLNEFHLKIKS
                     GRLTGPESQICYFYFQLFWFGRPYLENKKEYSDLSGNTFLDLLQKEFSFTITEEGRLK
                     FEIWLSIMKKRMRCTKKSKPDYSNLPVGLFQTTQFLLDLHTFLTRYFFQYAFPWNQNE
                     TLVFYLFMISNFTLDTHNSHVQEFLISEKYKDDVVAQLNRTFKQSIEEYFSFYVFPEE
                     ISQKIALTVMQNHAHFAYFRGWMNIFGQEGLKQRLTEVEDKQFLVLCERLVRQTFAIV
                     DFTEVDEENARFELFARYASILRTLIKQLELRLQIAYDLPYERLMADIVKEIIQEQLL
                     NTIKYDLVEYEKEKQYDIILTSQLKEYPSQKSAKVFVFTSNEYNYDFPYLNQFLKECY
                     LEKLNLRMNKT"
     gene            33634..34998
                     /locus_tag="ACG8LA_000148"
     CDS             33634..34998
                     /locus_tag="ACG8LA_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD/NAD(P)-binding oxidoreductase"
                     /protein_id="HFQ0202488.1"
                     /translation="MKIVIIGASHAGITAALNLRKLQPKAEVLLIDEDHKDGLGYVSN
                     GINLYLKGKIRSLAEVAHNMRTLQESGAKLITEWRVTELDPDKHQLILASKEGKNETI
                     TYDKLIVATGSSPVTLYKQIEAENVYTYKNLVQSKQVLAALKEAKEVVIFGAGYIGLE
                     LADALRNKGYIIHLVDYMPNVLSRYFDKDMINSFQNQLQTKQINFYPNEFLIDWKKSE
                     EKVVSVQLLSQAIKADMVIFSAQTRPNTTLLKEKVALYEDETVIVNEYLQTSDPDIYA
                     IGDIVPVSFDKNKRHLFLPLVTRAVHMARAVALTLSGQPTAYDLRQKITAAVIIDYFL
                     GTVGLTEDEAPFLEQNTGSCSGEFDLFPQYDEENKTVNAKLIYHPDTLEIIGGQLISQ
                     EFLLSDLNLLADIVKHKTTIPQLAVEDFGFLSEHTSRFHYLNELAFKVLAKRANSNRV
                     DKRL"
     gene            35169..36239
                     /locus_tag="ACG8LA_000149"
     CDS             35169..36239
                     /locus_tag="ACG8LA_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFQ0202489.1"
                     /translation="MFLALNEIMHSKLRYALVAGVMFLIAYLVFFLTGLAYGLAQDNR
                     TAVDKWEADSIVLSKDANSNLGMSMITKKIAEEVEGGKVAYLAQTPGVVTSKDSTEEG
                     KINVSFFGIDKNQFIMPNLVEGKAFDNDDEAVGDISLKEEYGLAVGDTVKLSGSDKTF
                     KLTGFTDHAKFNVSPVLYTTINAYQEIRFEKEDTSENARINAIVVRGKISNLPEDLEQ
                     IKISKFINELPGYNAQVLTFGFMIGFLIVIAAIVIGIFIYVLTMQKINIFGVMKAQGI
                     TGGFIARSVVAQTFILSFVGILLGLLGTVGTSLVLPDAVPFQSNWLFFGVISLLMLVV
                     AVLGALFSVRTIVKIDPLKAIG"
     gene            36254..36922
                     /locus_tag="ACG8LA_000150"
     CDS             36254..36922
                     /locus_tag="ACG8LA_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0202490.1"
                     /translation="MKAIEFKEVEKSFQDGDQVVKALKETTMSIDKGEFVAIIGPSGS
                     GKSTFLTLAGGLQTPSSGSVFINDQEFSNQKESERVKLRFKEIGFILQASNLVPFLTV
                     KKQLLLVDKIKHEHRQKEAKELFEQLGVDKLINKYPEELSGGERQRVAIARALYNDPS
                     IILADEPTASLDSEKAREVVDILAKESKDKNKATIMVTHDTRLIDKCDRIFMMEDGVL
                     KEKE"
     gene            36942..37520
                     /locus_tag="ACG8LA_000151"
     CDS             36942..37520
                     /locus_tag="ACG8LA_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFQ0202491.1"
                     /translation="MVHRYNKDTQQKILKEATDLFMSKGYLGTSTREIAQKVGITQPN
                     LYHYFGDKEKLYTAVLENHLKDVGKALREIVQTSETGFQVTLTKMAQFLIETHLVDLF
                     LMLHDLESNLSKETRDHLFFLWKKNYREPFEEIFSANQSVLRNGISKEIAARHFFLVL
                     APYITRSKRPVEEPLNVAQLIDLYLNGVLGEA"
     gene            37923..38834
                     /locus_tag="ACG8LA_000152"
     CDS             37923..38834
                     /locus_tag="ACG8LA_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HFQ0202492.1"
                     /translation="MKKIIGAFVFAIIIIIICFQIDVFGQKKIVGQTVSSTNSTVTKT
                     KESFDDTEQETLIKIGKNDRTLYTDDSLTTPLATINGGELAEFLSETKNAYQIKTNDG
                     YTGYLALEDGTKVTKNIQTKPEELSDAVIVLDPGHGGNDTGALSNDEQTEEKDITLST
                     AIKVKKALEDAGATVYLTHTTDELVQLGDICDYSEEKKADVFISLHADSTEYANEATG
                     ITTYYYYGQEETLAQTIADSFTDLPLDSRGISTGNYQVLRENLQPSILIEMGYMNNDS
                     DLKELVTDSYQQQIAASLTQALTTYFQ"
     gene            complement(39090..40007)
                     /gene="rnhC"
                     /locus_tag="ACG8LA_000153"
     CDS             complement(39090..40007)
                     /gene="rnhC"
                     /locus_tag="ACG8LA_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA];
                     GO_process: GO:0006401 - RNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HFQ0202493.1"
                     /translation="MSNVIIKATNDQLSQMKAYYRSYLLNKQIPYTSFAAKKDGTTIT
                     AYTSGKVMFQGTNAAIEADKWGEAQDKQAKPAKTASSLPKNISQLSVLGSDEVGNGSY
                     FGPLTVCAAYVKRDQLAELRKLGVRDSKELKDSQIIQLADILKKTIPYKLLVLSPEKY
                     NEIQPKYNAVRMKVALHNQAIHLLLKKIEPEKPEAILIDQFTPEANFKKYARLEKNQL
                     QEKLYFVTKGEQYHLAVAAASIISRASFLEELHKASAEAGITLPSGAGTKSDQVAAKL
                     LEKGGMPMLEKYAKLHFANTEKALKLLKK"
     gene            40209..40646
                     /gene="zapA"
                     /locus_tag="ACG8LA_000154"
     CDS             40209..40646
                     /gene="zapA"
                     /locus_tag="ACG8LA_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HFQ0202494.1"
                     /translation="MAHEKTRYKAVIANQTYTIIGRETKHHMDIVTKLINEQLAELKQ
                     LSPQMDNEQAAILMAVNALSDQLKKQERILELEEETAELKKKMIKFTELENRVKRIEA
                     IENEAREVLKENGQADHTIKNHVEAQQILNEKRKGQIKQKSSN"
     gene            40704..41251
                     /locus_tag="ACG8LA_000155"
                     /pseudo
     CDS             40704..41251
                     /locus_tag="ACG8LA_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629130.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_process: GO:0009403 - toxin biosynthetic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
     gene            41366..43726
                     /locus_tag="ACG8LA_000156"
     CDS             41366..43726
                     /locus_tag="ACG8LA_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HFQ0202495.1"
                     /translation="MNNRILETLEFEKVKQMVRQFVVTAQGKEELAELVPVSEKQTIT
                     NWLQETEDGLKVQRLRGGIPIPKLENIRPHMKRIEIGADLNGVELAQVSRVLSTTSEL
                     NRFIDDLSDSEIEFARLYMWADQLVTIPVLSRRLKEAIDEDGRVTDDASPELKSIRQN
                     IRRSEQAVREQLDGIVRGKNAKYLSDAIITMRNDRYVIPVKQEYRGVFGGVVHDQSAS
                     GQTLFIEPKQVVDLNNRLRQYQIAERNEIQRILSELSAELVPHRQEIIHNAYVIGKMD
                     LMNAKARFGKEVKAIVPGISEDNHVVLKQARHPLIDQEKVVSNDITIGKDYQAIVITG
                     PNTGGKTITLKTLGLLQLMGQAGLPIPAGEESQIGIFEEVFADIGDEQSIEQSLSTFS
                     SHMTNTVDILSKVNEKSLVLFDELGAGTDPQEGAALAIAILDDLGKKSAYVMATTHYP
                     ELKVYGYNRANTINASMEFDVDTLSPTYRLLIGVPGRSNAFEISSRLGLDTEVIDEAK
                     QLMNDESQDLNEMITDLENRRKMAETEYLEMRHFVSEAQELHDDLKEAYSYFFEEREK
                     EMEKAKKKANEVVSEAEEKAEKIIADIRKMQQQIGQGNVKEHQLIDAKTQLANLHQEE
                     TLKKNKVLKKAKEQKTLKPGDEVLVTTYGQRGTLLRKNGNQWQVEIGILKMNVSEDEL
                     TPVAPQKEPTQRVIHAVRSESSSHVPNQLDLRGKRYEEALSEVDQYLDSAILAGYPQV
                     TIVHGKGTGALRKGITDYLKNHRSVKSFEFAPANQGGNGATIVKFK"
     gene            43813..44127
                     /gene="trxA"
                     /locus_tag="ACG8LA_000157"
     CDS             43813..44127
                     /gene="trxA"
                     /locus_tag="ACG8LA_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015035 - protein-disulfide reductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HFQ0202496.1"
                     /translation="MSQVITDKTFNEETDKGLVLIDFWATWCGPCRMQAPILDQLEQE
                     YDEEEFRIAKMDVDENPETPQQFGIMSIPTLMLKKDGQVVEKAVGVHSKEQLRQMIDQ
                     YL"
     gene            44309..46087
                     /gene="uvrC"
                     /locus_tag="ACG8LA_000158"
     CDS             44309..46087
                     /gene="uvrC"
                     /locus_tag="ACG8LA_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009380 - excinuclease repair complex
                     [Evidence IEA];
                     GO_function: GO:0009381 - excinuclease ABC activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HFQ0202497.1"
                     /translation="MNERIKNKLALLPDQPGCYLMKDKNGTIIYVGKAKILKNRVRSY
                     FTGSHNTKTERLVSEIEDFEYIVTESNIEALLLEINLIKKNDPKYNIMLKDDKTYPFL
                     KITNEKYPRLVITRKVLKDKALYFGPYPDVGAANETKKILDRLFPLRKCKPSQTKEPC
                     LYYHLGQCLCPYYFDVDPKVYTKIVDEVKKFLNGGHEKIESEIHQKMEKAAENMEFEK
                     AAEYRDQIRAIETIMTRQKMTNTDLLDRDVFGYAIDKGWMCVQVFFVRQGKLIERDVS
                     MFPFYNEAEEDFLTYLGQFYQENEHFIPKEVLIPDTIDKPSVEALLATKVLQPKRGEK
                     KKLVELANKNASVALNERFDLIARKQERTIGAVERLGNAMNIPTPIRIESFDNSNIMG
                     TNPVAAMVVFIDGKPARKEYRKYKIKTVNGPDDYASMREVIYRRYSRVIREGLPLPDL
                     ILIDGGKGQVDVAKDVLENQLGIDIPIAGMAKNDKHKTNELLFGIDLAVVPLERNSPE
                     FFLLQRIQDEVHRFAITFHRQLRSKNSFASRLDEIEGLGPKRKKMLLKEFKSLKNITA
                     ATTEELQEIGLPKNVAQNVFDKLHQE"
     gene            46232..47131
                     /locus_tag="ACG8LA_000159"
     CDS             46232..47131
                     /locus_tag="ACG8LA_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0202498.1"
                     /translation="MLEVKDLVKTFGNYTAVDHVSFQIPDGKIMGLIGQNGAGKTTTF
                     RLILDFLTQDQGEVLWNGHHLGEKDYDVIGYLPEERGLYPKVTIQDQLLYFAELRGKS
                     RKEIEPKIDFWMEKFQVKGKKTDKVKSLSKGNQQKVQLIATLIHEPKLIILDEPFSGL
                     DPVNAELLKDGILELKKHGSCVIFSSHNMDNVEKICDHLIMLRNGKMVLNGKVHEIRE
                     SFGRTKLFLESGLSQQEVEEIEGVKKVILHEDNTLEITLEDPEAGKEIFTRATQFGYI
                     PMFNQQPPTLEEIFKLKAGEIDA"
     gene            47124..48386
                     /locus_tag="ACG8LA_000160"
     CDS             47124..48386
                     /locus_tag="ACG8LA_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFQ0202499.1"
                     /translation="MRKFWIITKDVYLKNVKSISFLIMILVPFIMLGIIYVAGNFAQQ
                     NSDVNKIGVLADNEQISQQMSQVKTDDFEFKAVDSEEKAQKELSEEKIDAYLVVSTEN
                     DKINGMLYSENSLGQSTQLLIQQQLTGLQSMLRASQLGISPEEVASLSQQASLTRQKV
                     NFDSKGKMTVGEDNSTVQYVVSYVATIVLFIIILTYAQIIAQEIASEKGTRIMEVILS
                     STTAQKHFYGKLTGVLLVALTQMALYGIIFGIGYSQFKDMEMVKNILDGISLDNLIGP
                     FLWYSLLFMIFGILIFSVLAALCGSLVNKAEDTAKAILPVTYLSLGGYMLGLILGASD
                     PNNIVIRITSYIPFLSSYIMPVRLANETVGMGGALISLLVLVAVTFLLMILSANMYKS
                     NVLVYSEGGLWSSLKQSISIMRNERKKA"
     gene            complement(48480..49772)
                     /locus_tag="ACG8LA_000161"
     CDS             complement(48480..49772)
                     /locus_tag="ACG8LA_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element IS1251 family transposase"
                     /protein_id="HFQ0202500.1"
                     /translation="MSYTHLIKETLDILDLSVTFNENCLTKEKYKGQICHIYRGNLIY
                     TAQECIHCKHQIASDIVRWGTTTVRLLMNDVSECRTYLELKKQRFKCKACQRTFVADT
                     SVAKKHCFISEKVRWSVVTRLKKNTSMTEIAAQKNLSVSSVYRIMKRFYRPLNPFRTP
                     LPKVLCFDEFKSVRGVSGAMSFIMMDGQTQRLLDIVENRQLPFLKRYFSHFSREIREA
                     VEWIVIDMYAPYVSLVKKLFPKAQLIIDRFHIVQHIGRTFRNHRIKETNQLLKSKEQK
                     HYQLGKQLKRYWKLLQKDERKLDYTRRLWRPGFKAHLTETDIVDRLLKGSPALRVGYQ
                     LYQDFLYAVKERDYVSFEELLTNNIMLPEGYQTTLRTFQKFLPQIKNALQQSYSNGPL
                     ECLNNHIKVLKRNAYGFRSFYNFKLRIMIRHGNALIFN"
     gene            50056..51954
                     /locus_tag="ACG8LA_000162"
     CDS             50056..51954
                     /locus_tag="ACG8LA_000162"
                     /EC_number="3.1.3.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042132 - fructose 1,6-bisphosphate
                     1-phosphatase activity [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphatase class III"
                     /protein_id="HFQ0202501.1"
                     /translation="MDRYLDLLSEKFPTTEDVITEIINLEAILQLPKGTELFLSDIHG
                     EFPAFDHILRIGSGNLKEKIKDLFSEQMTETEISQFTIFTAYPEYVLTTDWYKKQDKS
                     QLIHRLIDLLRFTTVKYTRSKVRKGLPKEYSYIIEELLYIDDRINGKKDYVKKIIEQL
                     VLMKEEEKFLTKLAQTIQKSVIDHLHIVGDIFDRGTQAAKVMDRIMDFSSVDIQWGNH
                     DILWIGAYCGSEACLLTLLRIAARYNYLFELEKEYGLNLRPLFSFAHQTYQKNPVFTP
                     KNRKDLSEREQEELEKIHQALSILQFKSEHQLLNRRPEFKMDDRKLLEKINYEESTIV
                     LEGQLYELKGTCFQTIQPDDPKKFLEEEQKVIDSLMYSFQHSLRMQKHMTFLIEKGGM
                     YLTNNQHVLFHGCIPVDEKGQLLAFELDQSYRGKELLGFFEKQITESAKDLTANEDLA
                     TDLIWYAWSGPFSPLFGKSKMATFERYFLTEPHTHVEKSNPYYHLRDEEWFSEKILAE
                     FDAKEEGSAIINGHTPVKVKKGESPIKANGKAFVIDGGLSKAYQKTTGIAGYSLLCNS
                     YGFQIVTHYPFLPIEQQFAKKSDQTNVKKVIEQQLPRKLNRNTTKGMELQQQITQLQR
                     LLDYRKDD"
     gene            complement(52253..52972)
                     /locus_tag="ACG8LA_000163"
     CDS             complement(52253..52972)
                     /locus_tag="ACG8LA_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HFQ0202502.1"
                     /translation="MKPIIGIAGNQLIRATDTFQGNQVSYTPQGFVDAVLDAQGLPLI
                     LPVMSPDSAPQLIEKIDKLILAGGQDVSPQLYMEDPHPKLTETNIQRDQFEQALILEA
                     LKQRKPIFAVCRGLQLLNVVLEGTLYQDLSLYPKWSVKHEQQPTAPQFATHEVKIVSD
                     SLLSDLLPDSYFVNSYHHQAVKDLSPLLKAIAFSNDGLIEAVQSKDNMHKILGVQWHP
                     ELSHRVDSSEQRLFDFFVNEF"
     misc_feature    53162..53209
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF03071"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="sodium ion sensor (DUF1646 type); this
                     cis-regulatory element may regulate processes involved in
                     with the transportation of sodium ions; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF03071"
     gene            53309..53641
                     /locus_tag="ACG8LA_000164"
     CDS             53309..53641
                     /locus_tag="ACG8LA_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202503.1"
                     /translation="MKQVLEALEQIRKAEEENEKRARTLRQQLKTYAEEKEQELEIIQ
                     TNSRQQLKQLVEEKEQFEKQELEKEKMKLKAEADKVQATLKDQYQKHQSQAIGAIIER
                     VKETYGRH"
     gene            53628..55631
                     /locus_tag="ACG8LA_000165"
     CDS             53628..55631
                     /locus_tag="ACG8LA_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HFQ0202504.1"
                     /translation="MAVTKMEKVTLISDKRNQERILQAVQGIQNVEIRDLYQNRTNNQ
                     WVEKYFPDTTIIDKEAKLSALGNRLKDIQEAIQFIQHHGDSRQKKLHLKRQELSLQDL
                     EANYSEENFMNKLEEVLDLKEKWEQLTEKRDRLEEEEEWLLHWQQLDIAPSMYASKTT
                     IFEMGTVSAANFESFKEELSKLDDVYMEEIDYTPKQVYLSYVALKKSVAAIEEIAGKY
                     GFNKETYPYEQNPKEKLQETKQQLSIVHEQQKKITTALGQCSGYIQEFEWVEEVTLAV
                     AEREKVKERFIHATYLIVLQGWVDAEEKQNLMHVLNETVSEEDIYVSFETPNSEEIQQ
                     EVPTKLKNHPLIEPFELLTEMYSLPKYEEVDPTPWMTPFYLVFFGMMVADVGYGLLML
                     IGTILAQKLFVLPRGMKRFVKFFEILSVPSIIWGLIYSSFFGQALPKELFGIRLPFPI
                     LSTTDDVNTILILSVIFGLIQILVGLFVAAKENIRRKDYLSAVSDGFAWQGILIGIVI
                     ALIGVMLIKNTAFVYLGAGLSIIAALCILIVPIIQSPSKVKGAAKGAYNLYGLTGYIG
                     DLVSYTRLMALGISGGSIGAAFNMLVAFMPPAARFSVGILLIIALHALNMFLTLLSAY
                     VHGARLQYVEFFGKFYTGGGRAFDPLKTAEKYVNINHKKKNNK"
     gene            55650..56120
                     /locus_tag="ACG8LA_000166"
     CDS             55650..56120
                     /locus_tag="ACG8LA_000166"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HFQ0202505.1"
                     /translation="MMDYLISQNGGMVFAVLAMATATIFSGIGSAKGVGMTGEAAAAL
                     TTSQPEKFGQALILQLLPGTQGLYGFVIAFLIFINLGNDMSVVQGLNFLGASLPIAFT
                     GLFSGIAQGKVAAAGIQILAKKPEHATKGIIFAAMVETYAILGFVISFLLVLNA"
     gene            56141..56725
                     /locus_tag="ACG8LA_000167"
     CDS             56141..56725
                     /locus_tag="ACG8LA_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit E"
                     /protein_id="HFQ0202506.1"
                     /translation="MNAIEKIISQMNEAAEQERAALEQEERMKIDQNFEQKRTQIETE
                     HQKQKEKQIELLEKKYRQLRNRQQVEVRQENLNAKQEFLRRLFADAIAEMENWDESEQ
                     IQFIKNSLYSLPLTGKVTFIAGEKSAAYLSQTLLDEWNNELPFMMVLSDETVADQAGF
                     LINDQGVQYNFLFSSLVQDIQGTMSFEIANQLFE"
     gene            56740..57726
                     /locus_tag="ACG8LA_000168"
     CDS             56740..57726
                     /locus_tag="ACG8LA_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046961 - proton-transporting ATPase
                     activity, rotational mechanism [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HFQ0202507.1"
                     /translation="MEYHELNPLIRGRELELLSNETFERMIQTNSVEALGEILKSTIY
                     SPYIYDGYEYDFEQNLLKEQSRLFRWLKESAPEPEIVWIYTMRYTFHNLKVLTKAEMT
                     NQNLDHLYIDDGFYSLETLKDAIHTQVSNELPESIMDSIREVRDYFEESTILQGIDVI
                     YDRQFLTEQRRLADKLGYQELLTEVIAFIDLTNITTMARGILQKRTYGFMTTVLSSSG
                     SIEKEVFLNFVDKDMEDYTNFLLETDYADFLRPVIREGNLDLVKLEQLKDDYLSSLYQ
                     EAQTQAFGPLPLLAFLNAKEVESKNLRLLVIGKRSHFEPETIRKRVRQVYDA"
     gene            57716..58027
                     /locus_tag="ACG8LA_000169"
     CDS             57716..58027
                     /locus_tag="ACG8LA_000169"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HFQ0202508.1"
                     /translation="MTHKIGVVGDKDSVLPFKLFGFDVRYGTTKQTVRQAIEEMAKNE
                     YGVIYVTEQCAALSPETIERYKEQMIPAIVLIPNHQGSLGIGLEEIQKNVEKAVGQNI
                     L"
     gene            58049..59830
                     /locus_tag="ACG8LA_000170"
     CDS             58049..59830
                     /locus_tag="ACG8LA_000170"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HFQ0202509.1"
                     /translation="MQIGKIIKVSGPLVMAENMSDASIQDMCLVGDLGVIGEIIEMRG
                     DVASIQVYEETSGIGPGEPVRSTGEALSVELGPGIISQMFDGIQRPLDTFMEITQSNF
                     LGRGVQLPALDHEKKWWFEPTVEAGETVSAGDVIGIVEETKVIKHKIMVPNGIKGTIK
                     TIEKGSFTIDETVCVIETENGDKNLTMLQKWPVRRSRPIKEKLNPDAPMITGQRVIDT
                     FFPVTKGGAAAVPGPFGAGKTVVQHQIAKWADVDMVVYVGCGERGNEMTDVLNEFPEL
                     IDPNTGESLMERTVLIANTSNMPVAAREASIYTGITIAEYFRDMGYDVAIMADSTSRW
                     AEALREMSGRLEEMPGDEGYPAYLGSRLAEYYERSGRVIALGSEGREGSITAISAVSP
                     SGGDISEPVTQNTLRVVKVFWGLDSSLAQKRHFPSIDWIQSYSLYSTEVGKYMDHILQ
                     ADWASMVTEGMRILQEEQQLNEIVRLVGIDSLSDNDRLTLEVAKSIREDYLQQNAFDD
                     VDTFTSREKQFKMLKMILTFGEEGRRALSLGAYLSEIMDGTVSIRERIGRSKYIPETE
                     LEKLDQIIGEIKQTMQTIVSEGGMSND"
     gene            59823..61199
                     /locus_tag="ACG8LA_000171"
     CDS             59823..61199
                     /locus_tag="ACG8LA_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HFQ0202510.1"
                     /translation="MIKEYRTIGEVVGPLMAVEKVAGVKYEELIEVRMQNGEIRRGQV
                     LEVQEDKAMVQIFEGTSGINLRDSSVRFLGHPLELGVSEDMIGRVFDGLGRPKDNGPE
                     ILPEKHLDINGEVINPVARDYPDEFIQTGISAIDHLNTLVRGQKLPVFSGSGLPHKEL
                     AAQIARQATVLDSSDDFAVVFAAIGITFEEAEFFMEDFRQTGAIDRSVMFMNLANDPA
                     IERIATPRMALTAAEYLAYEKGMHVLVIMTDMTNYAEALREISAARREVPGRRGYPGY
                     LYTNLATLFERAGRIRGLKGSVTQIPILTMPEDDKTHPIPDLTGYITEGQIILTRELY
                     KSGIQPPIDVLPSLSRLKDKGTGPGKTREDHAATMNQLFAAYAQGKQAKELAVVLGES
                     ALSDVDKIYAKFAERFEKEYVNQGFYTNRSITETLDLGWELLSMLPRTELKRIKDDML
                     DKYLPEGK"
     gene            61206..61841
                     /locus_tag="ACG8LA_000172"
     CDS             61206..61841
                     /locus_tag="ACG8LA_000172"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HFQ0202511.1"
                     /translation="MARLNVNPTRMELTRLKKQLTTATRGHKLLKDKQDELMRQFILL
                     IRKNNQLRQEMEESMTEAMSDFVLANASITEPFIEELFVLPAENVDLSIVDKNIMSVK
                     VPVMNFEYDEQLTDTPLEYGYLNSSAELDRSIDRFTTLLPKLLELTEIEKTCQLMASE
                     IEKTRRRVNALEYMTIPQLEETIYYIRMKLEENERAEVTRLIKVKNMGTTD"
     gene            61871..63226
                     /locus_tag="ACG8LA_000173"
     CDS             61871..63226
                     /locus_tag="ACG8LA_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HFQ0202512.1"
                     /translation="MIKQSKQIKKRLPAVQLLALGFFLLILVGGGLLTLPFFSNSGHG
                     TNFIDALFTATSAVCVTGLTTLNTAEHWNSAGQFLIMLLIEIGGLGFMMVPILCFALI
                     KKKVSLSTRIILKEALNLEEVSGVMKLMLYILKLAFVIQLIGTVALSFVFVPEFGWLK
                     GIWYSLFHAISSFCNAGFDLLGDSLANHQQNVYLIMVVSALIISGGLGFIVWRDLLEY
                     HQKKKMTIHSKIALTVTGTLLLGGFVVFFFTERNGATLVEGNMFQRLANTFFMSVTPR
                     TAGYYSVDYLHMSHAGLILTMFLMYIGGTSGSTAGGLKTTTLGVLLIQMRSMLKGRTR
                     AEAFGRTIRQGAVLRALTLFFVTLTLCVVAIMILSVTETIPKTSGIEYIAFEVFSAFG
                     TVGLTMGLTPDLTAIGKLIIIALMYIGRVGVLTVVFSLMTKAQRTQSKYKYPEESVMI
                     G"
     gene            complement(63418..64812)
                     /locus_tag="ACG8LA_000174"
     CDS             complement(63418..64812)
                     /locus_tag="ACG8LA_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HFQ0202513.1"
                     /translation="MPINSYDNYPLTWRPDKQKLKRPYYRSLIQQLEQDILKNKLQKN
                     TQLPSQRELADYLDLNFTTVGKAYKYGIEKGLLYTNIGSGTFISPNVFESITISTNEV
                     TEHIIDFGLVSSFEECNKFVVPFIQSTSNNPNLVGLLNYQDPKGTNFQLTTAANWLKT
                     QGVIPSLESLSIVSGVQNGLAITLSALFSPGDRIATDRYTYANFIELAQLYHLEIVPI
                     DFDEQGMRPDILIQECRKKKIHGVFLMPSCNNPIGFQISHKRREQLAEVIEKEGLWVI
                     EDDIHSFLTTYYQHTIIPPFQNLLPNQTIYLAGMTKFICSGLRVAYLVVPVHVQSKIE
                     QAIFNINVKTSGLDVEVITQILHSNEANRILETKLSLTKRANQLFDSLFKVEKPTNRV
                     PYYRILPVDPEIDPKIIENDFLANGIRLYHSRRFTTRAQPDAFVRISLSSNNLEILAS
                     GLSIVKEKIKKYEL"
     gene            64904..65875
                     /locus_tag="ACG8LA_000175"
     CDS             64904..65875
                     /locus_tag="ACG8LA_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HFQ0202514.1"
                     /translation="MKIINFEEVVASFSFEEAIQVMKKCFFDYESGKISQNPRLVEIL
                     PDGKGKNMFAMMPAYLGENRYFGTKVITAFPDNHQYHLPSHLGEIFLFDAQNGLPKAL
                     INANAVTWIRTAAVSALATDYLANPHAETLALIGAGQQALSHLTAISTIRPITTVFVY
                     DILEERRNTFIAKAKKQYPKITFINAISVEDAVRPAEIICTLTSSKEAFLQKEWVRED
                     AHINAVGTFTPDTREISTSLMETSQIYVDDYSAALTESGDLLIAMAEGDLEESCIVGT
                     LGELVSEKKTFYKGESRPTIFDAVGLAIEDLCCAEYIYNKLEKGALK"
     gene            65872..66654
                     /locus_tag="ACG8LA_000176"
     CDS             65872..66654
                     /locus_tag="ACG8LA_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HFQ0202515.1"
                     /translation="MNLDYYVVDAFADEVFKGNPAAVYVLEEWLPEGTMQKIAIENNL
                     SETAFTVKKNQEFELRWFTPDREIDLCGHATLATAFVLFNYYKIPDETIKFSTQSGNL
                     FVTRIKDYYYMDFPSIMPKKVPILSEYEEAIGAKIKEAYLARDLFFVLEDEKTVAKLQ
                     PDFTAIKNFELGIGVIVTAESVQKDFVSRTFFPKLTINEDPVCGSAHSNLIPYWAERM
                     NKTKLSAYQMSSRGGDLECELKEDRVIIGGKAVLFSKGTSFI"
     gene            complement(66823..67194)
                     /locus_tag="ACG8LA_000177"
     CDS             complement(66823..67194)
                     /locus_tag="ACG8LA_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFQ0202516.1"
                     /translation="MKMAHTCVRVKDLEASIEFYQKAFGFEESRRRDFPENKFTLVYL
                     TLPGDDYELELTYNYDHGAYDLGDGYGHIAIAADDLEKLHEQHKAAGLEITDLKGLPG
                     TAPSYYFVIDPDGYKIEVIRG"
     gene            67328..67771
                     /locus_tag="ACG8LA_000178"
     CDS             67328..67771
                     /locus_tag="ACG8LA_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HFQ0202517.1"
                     /translation="MDKPIFGEKKQFADYQTRYAAYIVIERDQQIAVIEAPNGAFFLP
                     GGEIEGEETKEEAIVRELIEEMGIVAEISSYLGEADEYFYSNYRATYYYNPGYFFVAD
                     SWKRIGEPTEKTNKIWWVSPQEALVKLKRGSHRWAVERWIEKNKN"
     gene            complement(67814..68623)
                     /gene="yidA"
                     /locus_tag="ACG8LA_000179"
     CDS             complement(67814..68623)
                     /gene="yidA"
                     /locus_tag="ACG8LA_000179"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HFQ0202518.1"
                     /translation="MSIKLVAIDIDGTLLNEKREVTKEVKEAIAAAVAKGVSIVLCTG
                     RPLPGVQEQLNELNLFQDNDYVITYNGALVQQTKSGKIIARHGLTHEDFLEIEVMARR
                     VGSHLHSIDDKAIYTPNRDISAYTIHEASLVKMPLKYRTPEEMTPDMNIVKMMMIDEP
                     EILDAAIARLPQTFRDKYTTVKSAPYYFEVLNKEASKGAAVANLAQHLGIDQDEIMAI
                     GDNENDLSMIEYAGLGVAMGNAVSLVKEAANVITSSNDEHGVAEAIKKYVL"
     gene            complement(68642..70009)
                     /locus_tag="ACG8LA_000180"
     CDS             complement(68642..70009)
                     /locus_tag="ACG8LA_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HFQ0202519.1"
                     /translation="MTTPYKYQMLPMEKVFRDPVHNYIHVQHQVILDLINSKEVQRLR
                     RIKQLGTSSFTFHGAEHSRFTHSLGVYEISRRICDIFSRNFSKEKIGNGGWDDQERLV
                     TLCAALLHDVGHGPYSHTFEHIFHTNHEAITVEIITSPETEVYQILNRVEEGFPEKVA
                     SVIQKTYPNPQVVQMISSQIDADRMDYLLRDAYFTGTEYGTFDLTRILRVIRPYEGGI
                     AFSMSGMHAVEDYIVSRYQMYVQVYFHPVSRGMEVILEHLLHRAHELYQEDASSFELH
                     SQLLLPFLDGSFTLEEYLKLDDGVLGTYFTQWSESADPILNDLAKRFLNRKPLKSATF
                     SGNRDSKLVQELTLLVEKVGYNPVYYTAVNSSYDLPYDFYRPEQGRHRTQIEILRNDG
                     TLIELSQVSQLVAALAGQEQGDERFFFPKEMVDPSLRDHYDLFDETYQEFASHIRNGA
                     LIEIN"
     gene            complement(69993..70823)
                     /locus_tag="ACG8LA_000181"
     CDS             complement(69993..70823)
                     /locus_tag="ACG8LA_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HFQ0202520.1"
                     /translation="MNPAIRLDQHIYQKNDFSPFALTDILTEYSKEHQQIFLHFWQYD
                     CTVILGMKDVRTPFLSDGIQTLKDAGYAPVIRNSGGLGIVSDEGILNISLIFPQSDTK
                     KITIDDAYEQMLLLTKYAFPKAPIQAFEITHSYCPGTYDLSIHGKKFAGIAQRRIKNG
                     ISVMMYLSVNGNQEKRGQVMKRFYQSALKEDFGTNGYPAVDPATMATLEELLDQPLFV
                     KEVKEAFAKAFEKLYSASDLQDSTDWLKKEIQLEQWNNQIQRMEQRNNIKELHYDNPL
                     "
     gene            70986..71423
                     /locus_tag="ACG8LA_000182"
     CDS             70986..71423
                     /locus_tag="ACG8LA_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HFQ0202521.1"
                     /translation="MELSQGTPISIKLRTKVKQQGEVQDFYFDLKGQMVTIGDTLYIR
                     YKEIQEETGDEIPVTIKLVPDGHVQLIRAGEMRMRLKFGYKERLETSYRTPYGMIQIA
                     TFTKELHVSLKDRPTGGKVRIDYDLFMGPEKIGEYYLTLDFTA"
     gene            71499..72119
                     /gene="rpoE"
                     /locus_tag="ACG8LA_000183"
     CDS             71499..72119
                     /gene="rpoE"
                     /locus_tag="ACG8LA_000183"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HFQ0202522.1"
                     /translation="MEISVFEGANKSELSMIEVAHAILEQRGDVMDFSDLANQIQNYL
                     GKSDSEIRDSLAQFYTDLNIDGSFISLGDNRWGLRSWYAIDSIDEEVNHGMDEEDEDT
                     PRRRKRKKVNAFINDDEDAIDYNDDDPEDTDLTEEDDDDLFDDDDDEDEEIAAYNSDL
                     QEIGADDPTDDEEDLPGNIEEDLSIIDEDDDDEDYEEEEFSDSEKE"
     gene            72308..72814
                     /locus_tag="ACG8LA_000184"
     CDS             72308..72814
                     /locus_tag="ACG8LA_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HFQ0202523.1"
                     /translation="MIFTGYKKKRQIEKYRHLLNGLIETDYQKMFRITMNYVHDKEEA
                     LDVMQDSFHKALNYFEKEKEIEHFSAWFYRILIRTALDSWRRQKRTPVDLFEIQDIPQ
                     QLPLETSVAELHMILDKIDSPEKEILILYFFEGFRLKEIATILDMNENTVKTKMYRSL
                     NALRQILE"
     gene            72831..73730
                     /locus_tag="ACG8LA_000185"
     CDS             72831..73730
                     /locus_tag="ACG8LA_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsiV family protein"
                     /protein_id="HFQ0202524.1"
                     /translation="MYSQKENLKKLKKTYKEQAIPKGLKEEIRQRFIIEEQSFIKAKR
                     RKRRLQGFGVSLAIVMITTSSLLFNSQVRSFAEDLPILGSVIELILGERFTDRSEKID
                     IQVPKINTQNEKENKTIHGLNQKYFREGQADFEKAEKEYGNFETDHYQVLGDYQKIVD
                     DNRFLVIERQITQTAADSHVEKRYDTIDKKNSVQLSLPLLFKDDTYLSVLTKEVKRQM
                     AEQVKEDPSKYYWTEQDIQEGTIEKPTLVTPTRSFYLNKEHQLVLTFSQYEIAPGYMG
                     TPEFVIPKSVTKTILASEDYLDH"
     gene            73817..74701
                     /locus_tag="ACG8LA_000186"
     CDS             73817..74701
                     /locus_tag="ACG8LA_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HFQ0202525.1"
                     /translation="MKRNYLVISIIALSVLLFFEITSVASLITEVKGQTHSSEHSSQS
                     FKQSEQSTIKSQSTETANVKEAIQESAEKVQSQSSQSTQDSTKTSRDPAVKSVAISFD
                     DGPGATTTPQLLRILKEKNVHATFFVLGENTAQHPEIVKQTAEAGHEIGNYTYDHQNL
                     ATLSAQSMTEEVTKADTEIKKVTGKTPTFVRPPYGSVTNVGATIIQRPIIEWSVDSED
                     WKTRNPDLILQKIQATVYDGAIILFHDIYPETIRAVPQVIDYLKEQGYRITTVGDLLG
                     HPTAVENYYGRNDHRPVQ"
     gene            complement(74893..74964)
                     /locus_tag="ACG8LA_000187"
     tRNA            complement(74893..74964)
                     /locus_tag="ACG8LA_000187"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(74929..74931),aa:Arg,seq:ccg)
     gene            75024..76358
                     /gene="rpoN"
                     /locus_tag="ACG8LA_000188"
     CDS             75024..76358
                     /gene="rpoN"
                     /locus_tag="ACG8LA_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HFQ0202526.1"
                     /translation="MKFEQNFSQKQQQTQKLAMTQQLQQSIQVLQYNSEELLAFVENQ
                     AMENPLVEVVEPEWQPDYIKASSSSYEGEETNYLNQIPDTKGSLFDSLIEQVHLNYRD
                     TFLRKIVLYLVEYIDLNGFLTISLEEAGKEIGATPIQMLDALTLIQQLEPAGVGARSL
                     QECLMLQTERDDYAPELAYIVLEECFEELVERKWKEIAQRFSVDLHAVQQIFDYLQTL
                     SPSPGRIFDRSSELYIIPDVRVLVDDDKNVQVISNRKNQPNIRFQESYFKQMSQQADK
                     ETENYLKERKQEFEWLKKTILQRGDTILRVAQVIVSRQKAFFIDKERPIKPLTLKEVA
                     TEIDVHESTVSRAVNGKYLETDFGVFELKKFFTTRIPTNSTEQTEDLSADTAKKKLQE
                     LVDQEDKNKPLSDQKLVELLKKDEIAISRRTVAKYRDLLGIPSSSKRKRYDN"
     gene            76507..77598
                     /locus_tag="ACG8LA_000189"
     CDS             76507..77598
                     /locus_tag="ACG8LA_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="central glycolytic genes regulator"
                     /protein_id="HFQ0202527.1"
                     /translation="MGRFKSTLDVKCPTKEIAMLDEIKMIESVAPDIIEVLQERYKIL
                     RNIYWMQPIGRRSLSESMGITERVLRTETDLLKNLNLIDTSKSGMTLTTKGEEVYQSL
                     ENFMDQLLGTHQTEQQLAEYFGNQRCIVVSGNSEEQTKVADAFGEALSEALDRLLPEG
                     ENIIAVMGGTTMAVVAEQLSNLENKKRHNLFVPARGGIGEAITVQANSVSARMAAKAN
                     GNHRALYVPEQLSLATYNSLLNEPSIQEVLNLISEANCVIHSIGRALHMAARRKMTEK
                     ELVMLKQANAVAESFGYFFNEKGEVVYKVPRIGIELQDLEKVPIIMAIAGGKSKAKAI
                     RAYMKNAPKQTWLITDEAAANEILKGVTL"
     gene            77639..78640
                     /gene="gap"
                     /locus_tag="ACG8LA_000190"
     CDS             77639..78640
                     /gene="gap"
                     /locus_tag="ACG8LA_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HFQ0202528.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIQDVDGIEVVAINDLTDAKMLAHL
                     LKYDTTQGRFNGTVEVHEGSFNVNGKEVKVLANRNPEELPWGELGVDIVLECTGFFTS
                     KSAAEKHLTAGAKRVVISAPGGNDVPTIVYNTNHETLTGKETVISGASCTTNCLAPMA
                     KTLNDKFGVVEGLMTTIHAYTGDQMTLDGPHPKGDFRRARAAAANIVPNSTGAAKAIG
                     LVIPELNGKLDGAAQRVPVPTGSLTELVTVLEKEVTVDEINAAMKEASNESYGYNTDE
                     IVSSDIVGMTYGSLFDATQTKVMTVGDKQLVKTVAWYDNEMSYTAQLVRTLEYFANL"
     gene            78750..79940
                     /gene="pgk"
                     /locus_tag="ACG8LA_000191"
     CDS             78750..79940
                     /gene="pgk"
                     /locus_tag="ACG8LA_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005228679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004618 - phosphoglycerate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HFQ0202529.1"
                     /translation="MAKKTVKDIDLKDKKVLVRVDFNVPLKDGVITDDTRIKAALPTI
                     NYVLEQGGKAILFSHLGRVKTEEDKEGKSLAPVAKRLGELLGKEVTFVPETRGEQLEE
                     AIRNMNDGDVVVFENTRFEDIDGKKESKNDTELGKYWASLGDVFVNDAFGTAHRAHAS
                     NVGIASTGIPTVAGFLMEKEIKFIGEAVEEPKRPMIAILGGAKVSDKIGVIENLIPKA
                     DKILIGGGMTYTFYEAKGIKIGNSLVEADKVELAKELIEKAGDKLVLPIDNVCAPEFS
                     NDVETQVIEGDIPDGLMALDIGPASVKLFADTLQGAKTVVWNGPMGVFEMSNFAKGTI
                     GVCEAIANLEGATTIIGGGDSAAAAEQLGFADKFTHISTGGGASLELLEGKELPGLAA
                     INDK"
     gene            80044..80799
                     /gene="tpiA"
                     /locus_tag="ACG8LA_000192"
     CDS             80044..80799
                     /gene="tpiA"
                     /locus_tag="ACG8LA_000192"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004807 - triose-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HFQ0202530.1"
                     /translation="MRKPIIAGNWKMNKTASEAKEFAEAVKNKIPSNDKVDSVIGSPA
                     LFLQELMTSAEGTELKISAQNCYWENSGAFTGETSPAALADLGVHYVIIGHSERREYF
                     HETDEDINKKAKAIFANGMTPILCCGESLETYEAGKTAEWIEGQITAGLADLSAEQVS
                     NMVIAYEPIWAIGTGKSADAQIADEICGVVRQTVEKLYGKEVSEAVRIQYGGSVKPEN
                     IAEYMAKENVDGALVGGASLQADSFLSLLDAVK"
     gene            80915..82213
                     /gene="eno"
                     /locus_tag="ACG8LA_000193"
     CDS             80915..82213
                     /gene="eno"
                     /locus_tag="ACG8LA_000193"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000015 - phosphopyruvate hydratase
                     complex [Evidence IEA];
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004634 - phosphopyruvate hydratase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HFQ0202531.1"
                     /translation="MSIITDVYAREILDSRGNPTIEVEVYTESGAFGRGMVPSGASTG
                     EYEAVELRDGDKARYGGKGVTKAVDNVNNIIAEAIIGYDVRDQMAIDKAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEVPLYHYLGGFNTKVLPTPMMNIINGGSHADNSI
                     DFQEFMIMPVGAPTFKEALRMGAEVFHALASILKARGLATSVGDEGGFAPNLGSNEEG
                     FEVIIEAIEKAGYVPGKDVVLAMDAASSEFYDKEKGVYVLADSGEGEKTTDEMIKFYE
                     ELVSKYPIISIEDGLDENDWDGFKKLTDVLGDKVQLVGDDLFVTNTQKLSEGIEKGIA
                     NSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTISDIAVATNAGQIKT
                     GSLSRTDRIAKYNQLLRIEDQLGEVAEYKGLKSFYNLKNK"
     gene            82612..83751
                     /locus_tag="ACG8LA_000194"
     CDS             82612..83751
                     /locus_tag="ACG8LA_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgE/DapE family deacylase"
                     /protein_id="HFQ0202532.1"
                     /translation="MKKEEKIAILQEIIRIKSVNGNEGEVAAYLNKLLAKHDITGEIV
                     SYRDGRDNLIARYQKGQSGKVLGLSGHMDVVAAGDESSWTYAPFAAEIHGNRLYGRGA
                     TDMKSGLAAMVIAMIELKESGKPFNGTVKLLATVGEEVGELGGEQLTKAGYVDDLDAL
                     IIGEPTNYSLMYTHMGSINYTVTSHGKEAHSSMPDQGYNAINHLNEFITKANAEMNHL
                     AETIENPVLGKTIHNVTLISGGNQVNSIPSHAQLQGNIRSIPEYPNDKIIALLQSIVN
                     ELNQETDYHLELMIDYNKIPVKADPDSPLIHCIQQQFSQPLPLVGAAATTDAAEFTKA
                     NHSFDFVVFGPGVVTLPHQVDEYVEIDNYLDMIEKYQGIILSYLA"
     gene            83863..>84062
                     /locus_tag="ACG8LA_000195"
     CDS             83863..>84062
                     /locus_tag="ACG8LA_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HFQ0202533.1"
                     /translation="MTYTHLTPNELVMIEAYFHQETPVAIVAKQLKRGRQTIYNVYNF
                     LKCGGTALEYFEQYKENKRRCG"
BASE COUNT        28259 a        14234 c        17458 g        24111 t
ORIGIN      
        1 agatttaaaa ataggtgaaa cttatcaggc agatggggtt gaactaacat ttaaaaatat
       61 tgaagtgacc gaaaaaagaa atgaatttgc acaacatgat cgtgtattac aagtgaccta
      121 tacacttaaa aatgatacag aaaaaccaat acgtccacaa caatggtcga ttgaaaataa
      181 ggatggtgaa gagctttatg agtatgctat gatattagat aatccagagt atattgaaag
      241 tgacaaagaa gaaacagtaa attactatta tgaattaccg attgaaaggc aggactacca
      301 aatcgtagta cgtagagcga atggttattt tgttggatta ccctttactt tgtaagtctt
      361 attttgttag tggcttttaa gttaatatca tttttgtgat ttttgaaaat gaaagtgagg
      421 aaattggaag aatggctgaa gaaaataaag ttgttccgtt tgaaacatta gtgataaata
      481 aggaagagtt tgagcaactt tttcttgatt tttttattca atatgacagg atttatgatt
      541 ttagttcgtc actagattta tttgaattag aagcagaaat aatagaaaac agtcgagaga
      601 agaatggtaa aatcattatt tcagtagaaa aattcaatga attattctca gaaacatttg
      661 aaatagatcc agactattat caaccacaag aagtttttcg agagtttaga aatcagatta
      721 ttcgttcaag taatattgaa aattgagtca ataaaagaag cgttgaagaa aagttccttc
      781 tttcgacgct tctttttaaa agattttaca aatgtcttat ggagatttgc ttcaatgact
      841 acttgtagtc atttcgttta aaataattat gttacaccct tatgtgtcac agagaaatac
      901 tgatataata agaaataagg tatgtaacaa tagagtatac ttctatgtta catattgatt
      961 attttgaaaa aatcatatta ggagaatata attatgagaa gtgatagtag gttttttgtc
     1021 agtaatttac aagatgacga gctaataagg cagattgatt cattattaga aacaataaca
     1081 gaatctgata aaagaatatt tttaaattat gtagaattaa cacgtcatat tatagagttg
     1141 gataaacttt ttaatgtgtt tagatataat ttaactaatt tgctcaaaca cttcacaatt
     1201 tttactaatg atttaattga aagtacaggt gaaaaattaa cggaagacca gtattattat
     1261 cagataaatg ctttgacgat aaacttaatt agttcagcca aaactttgac tgaatccatt
     1321 gaagtttgta tgaaaaactt tttagcagaa aaagatttta aatcttttaa gaataaaatt
     1381 ctgagtaagc cttatgatga gcatttttcg tataggtttt tattacatat gagaaattat
     1441 tctcagcatg gtcatctgcc agtaaatatt catcaacaaa gagtgtactt tgatttggat
     1501 gaaattctag caatgcctca ttttgatttt aacggacaat taaaaaagga gttagatgtt
     1561 ttaaggaaag atatatataa ccaatttaga gattccccac gtatctctta tgtttataca
     1621 gtagcgaaat ttaatttagt aataaccgaa atatatttca attatttaaa agagatcaaa
     1681 cctattttaa taaagttgaa tgacgagaaa aatgaattac tactcaatac caaatttcag
     1741 ttaattaatt cagatggaag ctcaagtgat atgctttttt atgagtttga tggtgagaat
     1801 tatcactgct tcaaccgaaa ggacaacagt atatctatgt atgctgacat aaaaagagaa
     1861 gttaaaaaaa tattaaaagt agaagaacaa tactataaag aaatagaaaa aagaaaccag
     1921 taattaacac agttatcaag gtaaagaaaa agttctcttt ctgtttgcta gttgtggctt
     1981 atgtagcaaa tatcaagtta ataggaaaat taaaattgtt gaaaggaaag aagttgatga
     2041 catattagta agcaagttgt tgaatattta tattatccta aaaaaggaag aatggaaaat
     2101 atcgaagaaa cctttctgaa agtgttgtca ccatatatta gtgattctat cttaagattt
     2161 caggagcagg aaaaaaatta taaatttggc tttgacataa agaactataa tgattcgtta
     2221 cacgtagtat ttcaatataa taagactggt aagataggaa taaaagaggt acatatattt
     2281 caaattttcc tagctaaggt caatattgaa gcaagtaaat caaaattaaa ctacactacc
     2341 cttttagata caaatgcgtt gtttttttcg aaaaaactat taccgtattt gcatagttac
     2401 gaatgggcat taagaaaatt aatctattta ttagctccgg catatttttc tgataactgg
     2461 gcagaggaat caattccaaa tgaaatcatt tcgtcaataa aaagaaaaca aatacaagca
     2521 ataggaaagt ttgactcaaa gaatctttta caatggatag atttatatga ttttgaagaa
     2581 tatctctttg gagaaaatta tattttagtt acacaagaaa atgaagagaa tattgtaagg
     2641 tataaagaaa tatctcagga tcaattattg aagttatttc aagataacag tcacactata
     2701 tctgattcat attctttgtg gagtgaagta tttagtaaat atatggatgt taagctagaa
     2761 gaaattcaaa cagacatgag tttaatcaga gaaggtagga atattgtaag ccataacaaa
     2821 gaaatagaaa tggctttata ccaaaaatta ataaagaaat tgaagagata tacaaatcaa
     2881 ctagagaaag cttttcaaaa aatattggct ggagatattg ctggtgagga ccttagtgat
     2941 atgtcagatg attttgaagg atatattgga aattatttta gtaatatcga tttagcaggt
     3001 gttactaaat tgtcagagtc tctatcagca atgaaagtat taaatacaga ttccatgaaa
     3061 aagtcgatgg agtcaatagg tcaaacatta tcagtccagc aagaaattat gcagaacttt
     3121 gatactgaag gtatcagaag ggcaacagag ggaataaatc aatctctaca atcaataaaa
     3181 atattaaata cagattccat gaagaggtcg atagagtcaa taggtcaaac attatcagct
     3241 ttatcagctc agcgagcaat catgcaaaac tttgatacta aaggtatcag aagtgcaaca
     3301 gagggaataa atcaatctct acaatcaatg aaaatagtaa atacagattc catgaaacga
     3361 tcgatggaat caattggtaa aatttcatca acaaaccaag tattgaagtc agagtaaata
     3421 aaacaggaac gatggcaatc atgttaccac acgaaatgct atcatttgta gcaagtattg
     3481 gatttagagt aattattata gagaggatga gataaaatgg ttcaaggact ttttggtgga
     3541 gggacttctt atgaaggtca atcgatttcg gacattaagg aagacgtcaa taattggaag
     3601 atatatacag aaaatgtaaa atcacagatt gttgaaaaaa aagaggcttt aattaagaat
     3661 ggtttttgga acaaaatacc atggaatttt caacaaacta ttaatgaatc aatcttctgt
     3721 ttaggaacat ttcttagtga ttttcagata gttgaatcag cttttgagga aaattttatt
     3781 tctgagagag agataaaact tctaaggaaa attggtaaaa attctgtgca atttaaccat
     3841 agttacggaa aatactttaa ggaagaatac gaatggcgcg aatatggaaa tccagaattt
     3901 gaaatcgttg aatcaattta ccaacatggg agagattttt ttgtgacgtt acaagatgca
     3961 agtaatgcag caggacgact ggaggactat atgagcaaca attcaatata taataaagta
     4021 aatatatttg gaaatagtta caacactaat atacagcaag gccacaataa taatatgatt
     4081 gtttctattg atgatatgtc ggaattatta tcaaagcttg atttgctttt ggagaatttg
     4141 aatgattcct tacctgaaga agaggtagaa gaggctcagg agtatatcga aaccattaaa
     4201 gatgaagcta ttaaagaaaa gcctaaaaaa actatgctga ggtttgcggt agatagtcta
     4261 aaaaaactta aatggagtac agaattctta gcttctgttg caacaatagc tcaacttgtt
     4321 gctccactgc tataagtgga gaatgaggtg ttcttcaatt aaccgacttg ccaagttgtg
     4381 gtaatggttt gagataatga aagctttgta ttctatagag attgatgtat ctgaatgaat
     4441 gcttgttttt ttggatatag ctgattaatc agtggtgtta cattatttat aagtcgtttg
     4501 attaactagt tcttacgatt tcttatcaaa agcacgccac gcaacttgaa tacgtttttg
     4561 aatacgacta aaaaaccact taaggtgaat tagacttaat aaagtgatta gttctattca
     4621 aaaatcgttg aaataccaac tatcgtcaat tatctttaat gagcttaact tcatggcgga
     4681 agaagaagaa tagactataa agctaggaga aaccttgata tgatagggtt tctccttttt
     4741 ttatttttta ctgtatgcca tattgtatgc catctagtca atatttaagt gttgtactaa
     4801 tttttcaaca gtcttttctt tcgtttcttt tgccaagtga ccgtaacaat cgatcgtctg
     4861 actaattttt gtatgccgta atctagtttg aacttctacc atagtagctc cagcgtccaa
     4921 gagcattgaa gcatgagtgt gtcttgctac atgcacaccg agaaatggaa ccatagcttt
     4981 ttcacaaata gtaatcaatc ttgcataaat agcgtggtgt gtgattagtt ctttatagat
     5041 accacaaaaa atcatagtcg gatcagttac accaagtgtc agcatatatt tccgctgatt
     5101 aatctgccat ttttttaata tagaaattgt tctttcatct agtggaagaa ccccagcact
     5161 acaatcagtt ttaggatcac tgattttata gccatttttg gattggctta gtgttttatt
     5221 gatggtgacc gtattttctt gaaaatcaat gtctgaccaa ttcaatgcaa gggcttcact
     5281 gatcctaacc ccgctataaa agagaaagcg tagtaacgtt ttatcaaagt cgtttcgata
     5341 agtttcaggt ttgctgttta ggtaatcaaa caaggtgatc agttgttctt tactgtaaac
     5401 tttgaccttt tctttatgct tagtggtggt tcttttaggc attaatacgt tgtctagtgg
     5461 attagtctca ataatcccaa gattgatagc gtagctaaaa atacgcttag aagttgaatg
     5521 aagtaccttg tattggtcag tagtttcagc ccagctattt acaatttgtt gggctttttt
     5581 taccgtgact tcattcacac gaagatttcc atattttgga agaatccact ttctaaactt
     5641 gatttcagtt ttcatgaagg tggcttctcg gacagtggtt ttatatgttt ctagccacaa
     5701 gtcataaact tctttaaacg tttcgttgtt cgctttttta ataccgtttt tatcgtagtc
     5761 cacttgcaag cgtgacaagg caagctgggc ttcttttttt gttttgtaac ctcgtctacg
     5821 aaccttatca ggtttgccag tcattttgtt cattccaaga taggcttcat agagccaaaa
     5881 tttacctttt ttagtttcat attgcttgaa tgttgccata atagttttcc ctccatagtg
     5941 tagcaagccg tgggggcggt tggaggaggc agtttattat tattttgaat agtgtttatt
     6001 tagctcagta acaagagctg tgaactcttt tagaagatca ttttcataaa attcttgata
     6061 ctcttttttc tcatctgtat ttttttctga atcattaatt aatgagtcat atcgtaaaag
     6121 cgtatttaga agagctgcga gataagcaat tggggtactc ccgtcaggaa attcaattcg
     6181 agatcctgtt ttaagatatt ttattgcgtt tgttaaataa atcttctgtg agacagtcag
     6241 gttatcttct tcgatgttat tgatagcatt agaaagatta gaatcaatta tagagttatt
     6301 tttttcaata gtttttttca attgcttttc aagcacattt cgcttaattt cgggcatcat
     6361 atgcatatct cttaatgtat aagatccgtt taatagatag gtagtggata catctaatac
     6421 ctttgaaagt tgtttaagcc tggtgttatt gggaagatta tagccatttt cccaattact
     6481 aacggcacct ttactggccg gtggggataa tttacctcca agttgttcca ttgagagtcc
     6541 cttttcaatt ctagccagtc taattctttg tcctgtctcc actgcttcgg ggtatttttt
     6601 tctagccaca ttttcaccac cattcatata ttttctctac tatatcacga tttaaatatg
     6661 tgtgaaacat aaaagttcaa aaaagtatgt taaaattctt gcaaatgaaa aggtatgatg
     6721 gtatattgag tttataagag gtatagaaat gtattcaaga gcctcttgca tttttttaaa
     6781 atctttgtat agaaatgtat gctaacgagg ggggataaat atggaattaa aaattgacaa
     6841 actcacgctt gatgatccag cttttaaaat tattgacgat cgagttgttc aacaagtaga
     6901 gcaaactcaa ggaacgttac tttcattatt agaaaaaaag taccagtttc caaaatatat
     6961 gaacaaggca caagctgcta agtatatgaa cgtttcatac aatactatga tgcagaaata
     7021 tgttcctaac ggtttaaagt tgattatagt tgatggagtc gtaagaattt cacaagatga
     7081 atgtgatcgc tttatggaag aataccaaaa ataaacgcaa gccgtggggg caaagggatt
     7141 aataggagga aataataatg gaatcgacac aaaataaagc aatcgaaaaa gtattatcaa
     7201 caattcttac agaagacaca gcggcagaat tagcaaactt ggaaggcaaa gcgctagaag
     7261 aaacgtttga atgtttgtac gaacaaatgg actatcaaaa attgctacca caagaaccaa
     7321 cggtaagcgg agtattgcgt ggcttgaacg atttagtaca agcagagttt aaagaacgac
     7381 tttctattga agagtatcaa gaaattttgt atcagcaagt tgagttgtta gcgagcttgc
     7441 tagggcttga actggaggac gttgaatgaa aactgaaatt tggaacggac acattataag
     7501 atttgtcgat attaatgatg aatggtgggc agtggcgaaa gatgttgcgg aagcgttagg
     7561 tcttaaacag gttactagag ccattcactc tttgcctaaa gatggggtta ctactagtaa
     7621 ggtcatcgat tcattgggca gaacacaaga tgtaaacatc atcaacgaaa aaaaatattt
     7681 accgcatggc attcaaaagc cgtaaaaaag aagccgaggc atttcaagac tggattttcg
     7741 acatcatcaa agaactacgc cagtccacag gacttgaagg ctttcaagta ttccgcatgc
     7801 tagacaaaga acaccaaaaa gaagcaatga ctaaattaag ccacgctatt actgaaccaa
     7861 aaccagtaga ctacattaaa gcgaatgtga tagccaataa agctgtatca actatttatg
     7921 gtcattccaa aatggtaaaa aagaaagata tgactcctga aatgttggtt gatcgtgaac
     7981 ctattttaga tgagacagta gaattaatga ctgttaaaga aaaatatggg ttgcagtttt
     8041 cagtgagtga gaaaatttat aatcgttctg ctgaattgca gacaacttag gagcattaac
     8101 atgatcgaga acaaagaaaa agccttatcc ataacagtct tggcggacag gataaaggca
     8161 acttaattgg gataaaaccc gatattcttt gttccgatta taccatatta aaaaatcgga
     8221 gggaaccatt atgaaacgaa acttaattat aggaagcatt ttaatcggcg gaattttcgg
     8281 cttattacca ttaattgcaa aaatagctat ctttgcagga ttagcgttat atctcttcac
     8341 tgcttatgac gagtacgact atcaattaag aactggaggg cataagtaga tgtacaaaac
     8401 aaaactatta aaccaactcg atagccttga attagaggaa attaatcaag ggatcgctga
     8461 actagaaaat aatatcggga aaacctactt tggaaattca ttcaatgaaa aactaacagt
     8521 tttgtatgta ctcaaaaaac atgcagaaca caaaataatt tgtcgagaaa tcaacgagct
     8581 aaaaaatcag attttaaccg catggttaaa cattactgat atgcaagaag caagggtgaa
     8641 aacatttaat acatgggtaa agtatcagaa tcaattaaaa ggtgctgaat ttgttcggga
     8701 tgggttgaaa tacgaacttg agcagttgaa gctcatggag gtgtctgaat gatttatacc
     8761 agtattttga aaaaggagga gaggtttatt ggcaaataat tatcaagcag caacggaatt
     8821 acaaaagtcg ggatggtcaa tttatccctt atctcctgga actaaaattc caataaaagg
     8881 ctctagtggt tggaatgatg caactaacga ttctaatcaa attaatgaat ggtggacgga
     8941 agatgcaact agaaatattg ggttaatgct tgaagatcat caaatggtgg tagttgacct
     9001 agatcaacat tctgaaacac gaaacggcgt tgagaattat aaaaaacttg cttcaatgta
     9061 tgatccattt ccttctactt atacggaaat cacaccaggt aaaggaatcc atttcttctt
     9121 taaaattcct gatggtgtaa ttatccaaca agaaacaggt gcatttgctg atatcttcgg
     9181 gcgtgatgat aaaggtaaaa gtttaagcgg gattgatatt atcactaaag gagttccaat
     9241 agcgccaact atgattattt caagaagtgt tgggagagca tatgaaccta ttgaaaacgt
     9301 atctctaaat aatattgcac cagctcccga ttggctagtg aacctactgc taaaaaaacc
     9361 gcaagaaata aagactcaat accgacccgt agcaaaaaca gggacagcaa aaaaattaga
     9421 tatgattgtt caaggcgctg gcgaaggtag tagaaacgat catttaacta agttatgcgg
     9481 ttggttacta tggcacggtg tagataatca aactttagca gaattgattt atacagcaaa
     9541 tgcgtacaat gaaccaccgc taaaagataa agaagtgaat caaattattc gatcgatgat
     9601 taaaaaagat ttgaggggga aagctcatgg ctcataagca taaattagat agtattttag
     9661 actttcccga agccagcgag cgtgaagaca atatcattga attgaaaacc tggatgtcac
     9721 gattaagatg caataaagac gatcagatta aaagtaacag tgttgtgaat gcagaattga
     9781 ttttaaccaa tgatagcaat ttagctggaa caattgctta taacgaattt agcggataca
     9841 ttcacctatt aaaagattct ccttggatca atcgtaccgc tggagaatgg gaagacagtt
     9901 ttgaggatgc cttaacggca tatattgaag aaaactacaa tgtagttttt gatgacaaca
     9961 aaatacacaa agcagtagta aatgtggcta gaaagaatgt tttcaaccca gtaaaagaac
    10021 gtatcgaaaa agttaaatgg gatcaacagc ctagactgga aacactgttt attgaccttt
    10081 taggggtaga cgacaacctt tacacacgag aagtaacaaa acgttggata gtcggatcag
    10141 tcgcacgtat ctataaacca ggaataaagt ttgagatcgt tccagttttg gatggaccgc
    10201 aagggattgg taagagtacc gttccagcat tactttacac ggatgatttt ttcaccgatt
    10261 cattagattc gctaggtgaa aagaaagatg attatatgca gcttcaaggc aatgtaatta
    10321 ttgaacttgg agaattatct tcaatgaaca aaactaaaat tgaacagata aaaaacttca
    10381 tcagtgccaa gatcgataaa attagacctc cttatggtcg gaatgtcata gcttgggcaa
    10441 ggcaatgtgt atttattgga acgtcgaatg atgggcagta tttgaaagat gatacaggaa
    10501 accgccgttt ttatcctttg ccttgtaaga ataagccaaa gatgaatccg tttaaaacaa
    10561 aggatgaata ttttcttcaa gtgttagctg aagcaaaggt gctttttgat aaaggacaac
    10621 gaatctattt tagtcccgat gaagataaag aagtcttaga aattgcaaaa gactatcaag
    10681 aggatgccaa gatggagaat ccaattaaag aagcaatcac taaatatttg gaaatggaaa
    10741 tcccgtataa atgggaagaa gctccagcgt gggcgagacg ttcttattat cagaactatc
    10801 ctgacagtaa atgtaatgag aaaaatttac agcatttcta taatggagct actatgcaac
    10861 aagagtttta tttagttgat agcgtactca ccgctgatat tttggaagct gtttttgata
    10921 aacaagcaaa ggatttattg aatggtcgat cagatgcaga aactaaaaag attgccttga
    10981 ttattagcag tattcctggt tgggaacgga agcaactgcc aaaaagaaat aaacgacgag
    11041 gattttacaa taagtcaaat gcctatgaaa ataaaaatcg agctggaaag tacaaaaagt
    11101 aacgggtagt aacgggtcag taacacctag cccgttacta gtttaccctt actgccccaa
    11161 gggatacagc aatttggtaa cggggtaaca ccttatttcc ttaaaacttt tgaaatagtt
    11221 agctaatatg ctggggaata atgttactgg attttacccg ttacctgtta ccaaaacgct
    11281 agaacccttg tccccgttgg gattgagtgg taacgggtac ctgttacgta ggtgttacca
    11341 cgtgttacga atcaaggagg aaagtaaatg ctcaatatta tttcaacaaa caaagcaccg
    11401 aactttcaat atacagatga aatggatcgg tttctaatga acacgctggc atttagtgtg
    11461 ggattggtaa cagaagatta ttccacattt gatccagaag tattaaagat aatggaagaa
    11521 gaacctgatt ggctgcagga gtcagtagcg tggtgtcaat cgctagtagt gggatcattg
    11581 gtagatagtg gcaactatga tgatacaggt gagctaatgg atgaatttaa ttgtctgctt
    11641 aacctatatg atcgagcgag acaacgagag cttacatcga atgaggataa tttgttttta
    11701 aacatccatg ataagttctt ggctttgcta ctaacagatg atgaattgat aactaattta
    11761 ttggaggtag aataattatg catatggaaa gtattagata cttcgatggt gagaaacaca
    11821 ttgagtattc aaacactcaa gaagatgtag actttattag ttttgaggaa gataaaatca
    11881 ctaaagttaa ttttaaagac ggaacgtgct tgaagatagt ttcgccttat attgaataca
    11941 aatcaaaatg ggaacaagat gattctgacg aacgagatcg ctttggttgg taatctatgg
    12001 cagttaaaaa acaatgtaat catgctggat gtaaaacatt gattgattat aggcagaagt
    12061 attgtgggaa gcataaagca aagcaaacgg caattaagcg tgaagaaaga aagcaaagcg
    12121 aaggtaaata ttttcaattc tatcaaagta gaacatggcg aaaggcttca tacttgtatc
    12181 ggttaaatca tccagtatgt gaggattgcc tagaagaagg cttgataagg aaagctgatg
    12241 ttgtagatca caaaattgaa ctaaaagatg attggaatag acggttagat gaaactaatt
    12301 ttcgttcttt atgccatgca caccataatt ccaagacagc caatgaaaga caaagacgag
    12361 aaaagagtac cctttgagtt aagggggcat agtgtgaaac ttactgacaa tcgatgccta
    12421 ctcattttgg tacaaataac cgttgtgaaa aggcataagg gtaattacaa ataacgatta
    12481 cacttgtaat cacaagtgaa aaagtatata atgaaagtag gagatttatt gaaaaataca
    12541 attgttatta ctgataaaac agggaaacag cgcaccattg agttacctca ttttggtcaa
    12601 gtgaccattc aaatgcagaa cggaaaaatc atttatatag ataaattaga taaagaaaaa
    12661 ttctgatcga aaaacgaagg aatgtgagct taattgctta cgttcctttt tcttttgtct
    12721 gaaaggagga caacatggga caccctaaaa tattacacga tacaaaaggc aatatatcaa
    12781 gtgaagaaaa agcaatccgt gtggacgcta gagaagaatt gttcaagcag caaccattaa
    12841 taaatatcac gccccctgac tggatggcag cgagcgctag aagtgaatgg aatcgtatcg
    12901 taccaacatt aaaaaaagat tatccattga gtgaagcaga ttatggttca ttggtagcct
    12961 attgtttagc ctttgctcga atgaaaacag ccgaagccga gataagaaaa tcaggtacgt
    13021 ttatcacatg cgaaaacgga gtaaagaaag ccaatccagc ggttcgggtt caatcacaag
    13081 ctatgagtga tttgaaaaaa caagccacct cactaggtat gaccttagaa tcacgatcaa
    13141 aactagcttt gaacaaggtt aaaaatgatg aacccgaaga cccgttcaaa gagttgatga
    13201 attcatgaat gattacattg agaaagtcct atcaggtaag ctgattgcac ccaagaaaat
    13261 tatccaagcg tgtgagcgtc atataagcga tttggagcgt tctaagtcag atagcttccc
    13321 ttatgtgttc gatgaagaac aagccaccaa agcgattaaa ttcattgagt tgctaccatc
    13381 tacggacggt aaagcaatca agatgttagg atttcaaaaa ttcattctag gcagtcttta
    13441 tggctggcgt actaaagaag ggaattacag gcgattcaat cgagcgttta ccagtatgag
    13501 ccgtaagaat gggaaaacgt atatcgcaag tggcatggct gccaatgcgt tgattatgga
    13561 acaagaacca gcagaagcaa ggcaagtatt gtttgtaagt aacgctttga aacaagctaa
    13621 attgggctat gatatgctgt ctaattcact tagaaacgtg gtcaagtcta gtaagttttt
    13681 aagaccacaa ctgaaaatta tgaactctaa gattcagcac ttgccctcta attcgttcgc
    13741 tatggcactg gctagtgaaa ccagcacgct agatgggttt gcaccaacaa ccgcaattct
    13801 tgacgagtgg cacgaagcaa aaactcgtaa aacgtacaac gtcattaagt caggaatgac
    13861 ccaacaaaag aacggcttat tgtgtgttat tagtaccgct gggcttgatt taaacgttcc
    13921 tatgtacgag gaatacttat tgttagatcg tgtgctaaaa ggcgaagaac aagccgacag
    13981 gtactttata gcgatatggg aattggacga tcccgaagaa attcacgatc aagagaaatg
    14041 gatcaaagcc aatccgattt ttgaaagtga agaaatcaaa aaagtaatga ttccaaccat
    14101 tcaagatgat gtgaaccttg ctttgaaaca aaataacctt aattctgtat tggtgaaaaa
    14161 cttcaattta tggagacaag cgagtgagga cagctatatg attgctgaag actggcaggc
    14221 aaccgaagta gaaccacaag atattacagg caagcccgtt tatatcggag tggatttatc
    14281 taaaacagat gatttaacta gcgtttcatg gatcgtaccg ctagataacg gcgaacttta
    14341 ttgtgattca catagctttg tagccaccaa atatgggctt caagacaaag aaaagcgcga
    14401 cggtttgcct tatcgagaac tagaaaaagc tggtgagtgt tccattactc aattagaaag
    14461 tggaatcgtg gactatgacc aagtatttca gtttattcaa gatttgattc aagaaaatga
    14521 tttggaatgt atggggattt gttatgaccc gtataacgct aattcgctta tcagtaaagc
    14581 tgaaaaagcc aactacccaa tgttagaagt aagacaagga acgattactc taaacgttcc
    14641 gacccgaact tttagagaac aagtttatga aggcaacgtt attcacaata aaaatacgat
    14701 tctcacccat gcagtgaaca acgctatttt aaaaacggat aacaacggca ttcagattaa
    14761 taaatcaaag aacagtaaca aaattgatcc aatagctgca ttaatcaatg cctatgtgtt
    14821 tgcaatggat tacttcacca caacggaagg agcgaaagca gacaatgaat tttatacaag
    14881 tgaagaattt tctttctaat tacattcata ccgttctttt acttcttgga ttggtgtgtg
    14941 tgttggttgc tatcacctta ctaacaaatg tctactatgg cttgttagcg ctgggcatag
    15001 tgcttattgg ggtagcggtc atgctaaata cagaacagaa gggaggttaa aagatggcat
    15061 tttttaaagc gagacaaaat acaacgggag atcctttcct acaacatgtg gtatcaatcc
    15121 aatcggatga ttacaccacc agctttacaa gcgttcgtgc attaagaaat agtgatgtgt
    15181 ttgcagccgt tcgaattatt gctagtgata ttgcttcaag tccgattcaa ttggtcaaaa
    15241 acaatatgcc acaagctgat aatgaactgg tgaagttact aaacgagaaa cctaattcag
    15301 aaatggatgg ttggcattta aagtttgctt tggcggtcaa tatgttgcta aacggtaata
    15361 gctttgcaga gattaaacgc aacggtgaaa aggtagaaga aattcactta ttacctaact
    15421 caagtgtaac ggttactcaa ttagataatg gtacgttgtc ttatcagatt ggtgataaaa
    15481 aaagacgtgt gaagtctagc gatattttgc acttcaaata tttcacccaa gatggtttaa
    15541 caggattacc accactttat gcgttacgtg atgaactgaa aattcaacaa gctggcaacc
    15601 gcacattgca caatttcttt actcgtggtg tcagtgggtc aggtattttg aaggttcata
    15661 agtcagattt agacggatca gcaaagaacg caattcgtga aaagtttgaa gaagccaacg
    15721 gttcaagtag tggagataat gctcttagaa cgatcattct tgatgaaaca atggactaca
    15781 aaacattaga aataaacacc gatgttttga agcttatcaa ttccaatgat tggaacacaa
    15841 aacaaattgc caaggcgttt ggtgtaccga ttgagcgttt aggcgttgaa aatgaacatt
    15901 ctagcaccgt tcaaagtaat ctccagtata tccaaagtac gctgattcat tactttaatg
    15961 tgtttgtgag tgaattagat acgaaacttg aaaccaatat ccgctttaat tccgatcagt
    16021 tactagagac tgatcctgaa acaaaagtaa aaaatgtatt ggatcaggtc aaagggtcac
    16081 ttctcacgat taatgagggg cggtcgaaaa tggggctacc ccccatggat ggtggcgatc
    16141 gtttactagc aagtttgaac tttacgtatt tagatacgtt ggagaaatat caattaaaag
    16201 aacaggaagg agttacacca gttgaataat gaagaagaaa aggaaaaacg gctgacagaa
    16261 gaagctgagc taacagccga ttctcccaaa gtagagaaag aaaatgaaaa acaaccaaca
    16321 gacggcaaaa ctatttcagg ctatgcgttg aaattcgggc aaccgtcaaa agatttaggc
    16381 ggctttgtag aagtgattac acccgaagca ttaaaagagg tggatttatc aaatgtgttc
    16441 ttattatatg gacacgatta ttcaaagcca ctagctagtg tcaaagcagg tacgttgaaa
    16501 ttgaatgtcg atgatacagg attacatttt gaagcagagc taaccgacac gacctattca
    16561 aatgatgtgt atgagaatat ctcaaaaggg gttgttgatt ctatgtcctt tgggttcgtg
    16621 cttggattag attcattcga caaaaaagaa gatggcacaa ttgaacgatc aatagataaa
    16681 atcaaagcac ttaatgaaat tagtgtcgtg accgttcccg cttatgattc atcaaatgtc
    16741 caagtaaata agcgttctta cgaatcgttt atgagtaaca accaagcaaa acaaacaaac
    16801 aatagcttag aatccacttc taaagcacaa aaggagagta ataacatgga aaaaacttta
    16861 atcgataacg aaaaaacaga attgcgtggg tatgaagaat atatccgttc acaaggcgaa
    16921 gtgcgtgatg gagtcactac tgtaaatgca gcggcagttg ttcccgaaga agtaatcggt
    16981 gaagtctttg atttgaaacg ttcaaattat aacttagctc aatatgcaac agtaaaaaca
    17041 gtatcaaatg gacaaggtaa atatccagta gcaactaacc aacaagcagt gttagcaaca
    17101 aaagctgaac ttgctgaaat tggtgatatt gacgctgaaa tgtttacttc agttgattat
    17161 aaagtagaaa ctcgtgctgg taagattgcc ttatcaaatg aggttgtgga agattcagca
    17221 gtgaatattg tacaagaggt caaagatcag ttagcgaaat tggtagaaaa cactgacaat
    17281 aagcatatca tggatttatt aaaaacattc actaagaaaa cggctgctac gttggacgat
    17341 ttgaaacaac tatacaatgt ggcattagac ccagcattaa ataaaatggt aattctaaac
    17401 caaagcggat attaccacct agatacattg aaagattcag atggacgtta cattttacaa
    17461 cccgatgtga cagcacctag tggtaaatca ttattcggta tgccagtagt attgattgca
    17521 gatacattgt ttgccaatcc taaagctgga acattcccta tgattatggg ggatattgca
    17581 caatctatct ttgttgctcg tagaaatcaa gtaacgactc aatgggaaaa attcgattac
    17641 tactcacaag gacttgcagt gatcgttcgc aacgattata agaaaattga tcaaaatgct
    17701 tcagtgtata ttgagtttac gccagttgta acaccaaaag tatagaaaaa tattgggcgg
    17761 cggtttatcc cactgccttt ttttcattag gagagataaa atggtaattt tggatagcat
    17821 aaaaaaaagt atgcggatcg atcacactat tgatgatgac tttattcaac aattgattga
    17881 tacagcaggc gaatatataa aaagtgctat tgatagtagc gcaacggata aagatatgga
    17941 taattatcag caatttgatt tggcggtgtc attacttact caacattggt atttgaaccg
    18001 tcaagaagcc agcagcgaac ggataccagt aacggtacaa gcattagtac aacaaatgag
    18061 aggtgcttat tatgccaatc attaagaatg taaatgaatt gactgagaga gtcaagttta
    18121 aaaagacaaa acgggtaaaa gatgaagatg ggcagatggt ggatagtgaa gaaactgtat
    18181 ttgaatgttg ggctaatgtg cgttcacaaa tgctaaaaga cgtgcttgct agtgtaggta
    18241 ccattcttga aggaacgttg acgtttatta ttcgatacga tcaagattat gaactaacaa
    18301 acgatatgaa agtagcttgg aaaaacaaga gttataaaat tatttcaatc aatgaaggaa
    18361 cggcgtttaa agattataca acgatcatag ctaaacagat ttcttagaat gattacactt
    18421 gtaaacgttg tgggtattta gtataattaa ggtagtaaat gaagggttag ctgcctgaat
    18481 tttgcaagac ttagctagtc gaaatctatt gttggactga aaattgtagg tgtggttgca
    18541 aacatgctgg actaagaaag atgatagatg atgaacgttc aattttaata caggcatgct
    18601 aggactgatt ggatggtttt ggcaagctga ttgtgtagaa atcaaagaac acgtctgttg
    18661 tggacgtgtt ttttttgtta taattcaaaa gaggtgattt aatggacaaa gcagagttta
    18721 caaattttta ttggaagtat tatctacatt tagaaaatga gtttattaat accacagatt
    18781 ttgtgatgct cgatgagaat aatttcaaaa cattctctat tgaatatcaa aaactactac
    18841 tagcgattgg ttcggagtgt gagattattt tcaaagaact ttgcggattt gatagcagta
    18901 gcaataaaag cataactgat tttaaagctg ttattaaatc tagcgaatta atgtgtttgg
    18961 ataatggtgt tagggttatg aattctttaa cattgacttc actaaaacct tttggagatg
    19021 ggtggcctga agatacacca gattggtgga aaatatataa cagagtaaaa catggtcgtt
    19081 cttcaaatta taaggaagca aatttggaaa atgtgttgta tgctttagca agtctatatt
    19141 tattagagga atatttgcat aagaaagtaa tactagaagg tgaagtagac tttataagtc
    19201 cagagtcaaa tctatttacg ttatcttggg aaagaaaaca ttcgtcgatg caaaaagtga
    19261 cgtttgaaaa agtggattca aattatgtag ctccactcat tgattttaaa gaacaagaag
    19321 aaatttaaaa acccccacgg cttattgaag tttttgtatg ccatattgta tgccatttgg
    19381 tttaaatcgc ttgaaaaata gtgatagata actctaattc atttagtcat aaacgctgtt
    19441 ttgataacct ttatagttct ttgatatggg tttctcattc atggcggaag aagaagaata
    19501 gaacaaaaga atgaattaat aagatataaa aaaagggatt gtgacaaacg tcttgtcaca
    19561 atcccttttt ccaaataaac gatgttcaat cagctgcccc tcggcattcg ctcgaaaaac
    19621 ggcgaaatat gaagaactat tttgccattt gtttctctaa taatcaggtc aaaacgttga
    19681 cttcacagtc tcttccttaa acggtgttct cctgccaact cctcggtcac aagtcacaat
    19741 attcaacaaa catgagaagc tgttttttga aattgttcct tgtgactcgg agctgaacgg
    19801 caggctcacg acctctttct taaacggtgt tcaaaagctt gcatctgcgg taataagttc
    19861 aaccaaacga aaattatgag gagctatttt tgtttggctg ttcttattac ttgatgcagg
    19921 acagcttttt cacaacctct tttcgtttag cactaaattt ccttaaaaag tagaaaagct
    19981 ttcgaagcct cgtttgtttc ttttactgta taataaaaga aaagagtaac aatcgctaaa
    20041 agatataaac aagagaaagg aaatacaaga tgattggtct gatttatttt gtggtgatcg
    20101 ttctggcgaa cacagttggc gctatttccg ggatgggtgg aggcgtgttg atcaaaccga
    20161 ttcttgatct tatcggcgcc cattctgttg cagggatttc tttttactca acagttgcgg
    20221 tattcacgat gtccattgtt tcgactgtgc gacaagtatc aagcgggaaa tcactgaatt
    20281 ggcagattgt cggttgggta tctagtggag ctgttgttgg aggagtagtc ggcaacattg
    20341 tattcgaagt ttttttacag ttatttgaaa acgagaagca tgtgcagctg atccaaattt
    20401 ttttgacggt attgaccttg gtttttgcgt tcttctacac caagcatcat cagccaaaat
    20461 ttcatttgac gtcatggact tggtacctta tatgtggggg ggttctgggc tttttagcta
    20521 gttttttagg tattggtggt ggaccagtca atgtttcttt gttgatgctg atgtttgcat
    20581 tgccaataaa agaagcaaca ctatattctc tatctacgat tttcttttct caactggcaa
    20641 aattggtaac gattgcttta acaagtagct ttatgcgctt tgatttatct atgttgtttt
    20701 atgttatccc cgctgctgtt attggaggtt tgtggggagc aagatttagc agggttttgt
    20761 ctccaaaaaa agtgaccttt atttttcaag taattgtcct cgtggttctt ttggtcaatt
    20821 gttacaatgc ctttgtcatc ttacaaacat taggagaatc tagactaacg caagtcaaaa
    20881 tcactgaaac atattgttct aaatgaaaaa aagagtatac tatgataaaa aaattcattt
    20941 taaaaaatca gaaattggct ggtgatttgg atgttacggg aaatgcgttt agaagatgca
    21001 gaagcactac gtgaaatcaa tgcggatcaa ttagggtatg atataccatt aaccgttacg
    21061 gtgagacaaa tgaagaaact gctgaaggag ccagagaaaa attttttctt ggtttatgaa
    21121 gatcctactt ctaaaaaagc agctggctat gtacaagcgg agtcctatga atcgattttt
    21181 agcgatccaa tgttcaatat tatggcactt gctgtgtcta aatatgctga aaaaagaggc
    21241 atcggaaagg ctttgatgac tggcgtagaa gaagaagcga aaaaacgagg aataacgaca
    21301 ataaggctta attctgcaga atacagagta gaagcacacc aattttatga acacatcggt
    21361 tatcattccg ataaaatgca aaaaagattt ttgaaaatcc tgtaaatctt tatcaaaaaa
    21421 atacccgatc accaagccga tacttgatga tcaggtattt ttgttttttt gactaagaaa
    21481 gtaattgcat caagaaacca gagatgatca aaacgatggc accaccaagt cgattgccca
    21541 tttgagcaaa agcaataagt tccatccgat tagctgcaga taagacggct acatttcctg
    21601 ttccgcccat cgagttgttg cataagccag cagtaatagt tgattcaatt ggatataaac
    21661 caaacaaacg accgacaaat cctgaaacaa ctgaaatcgc gataacactt gtcagacata
    21721 agacaacaaa ttgccatgtc aaagcagaag ctaatacatt cagattcagc aacgcaatac
    21781 cgataccggc aagaacagct gctgtcaagt ttttgacaat caagttattg aacatgatag
    21841 ctgcatcttc ataatactct ggtaataggt tggcgatttt acagatgaca acgataataa
    21901 tcataaatgc gtaagcatgg actttaggaa caaaatagtt accaatttgt cctaagatga
    21961 agaaagtcaa tgataccatc aaaccaacac ctaactgtgg aatggaaggt ttcacagttc
    22021 gaggttttcc atcgccaaga tcgccttttt ccattaattt accattgccg ttgaattttg
    22081 gcattgattg tccagcacga gcaactaatg ctgcaccgat gatagctaag acatttgtca
    22141 ttgctgtcgc aggaatcagg cgggaaatga tagaagaagc atccgtacct aaaacatttg
    22201 cataaatcgt tgataaagga acggctccgg ctccaacacc accagccatc gcaggtaatg
    22261 agatgtataa aacggaattt gcaaaaccat ttccgataag catgcccacg agtcctacgg
    22321 caaaaaagga gacgaccatt gaaataagtg caacgggaat aaaacgaaca gaagctttca
    22381 tcaatagatt acggttcata ccaaggatgc taccagtaat caaggcagca atataaaagt
    22441 ccaaaaagcc catattgctg acaaagtttt ctgtggattt cactacatat tcaggtaaga
    22501 tcccaaatgt agcaatcgca gcagaagcga agatcgcaaa aacggaacca ccacccaaat
    22561 aacttttgac gatagggatt tttgtcccga taaaatgaaa taaattaccg aaaataacca
    22621 aaactgcgat tggtccaatc atattcgtcg gtaatttccc taaagccatt gcaatgatca
    22681 ggacaaggac catgatcaaa taaagtggca aacttacgcc ggtgattttt gtggaccaaa
    22741 aaccttcttt tttcttttcc tcaactgcag ttgcagttgt tgttttttgt gccattttta
    22801 cagatccttt cttattctgt atcatatgaa aaaagccaaa gaaaagcgac aaaagagcag
    22861 gagttggctg gccgctgttt tgccgcagtc gcttttttct ttttagacgt catacaaagt
    22921 ttctgtatgt tcttttacta taacgatctt aatcttctaa agatttatat tcaggaaccc
    22981 atttagcaga ttcaactgct tctttgatat ccgtgatttc ttcacgattc aagttttgtg
    23041 cgacaactga ttttgcgaca gtttcagcaa tcgtttgaga aaattcagtg atttttgcta
    23101 ctggaggcaa gatagctgct cctggttttg ttacatcaac gattccgcct aatgctcgac
    23161 tagcttgaga aatgatttca gcatttactc gtgtagctgt tgaagcaatc aaaccaagtc
    23221 ctaaacctgg gtacatcaaa gcattatttg cttgaccgat ttggtaagtt acaccattat
    23281 attcaacatc agcagcaggg atacctgttc caactaatgc ttttccgtcc gtccattcta
    23341 ttaaatcttt tgcttttgct tctgccaatt ttgttggatt agacaaaggc atgatgatcg
    23401 gacgtggtgt atgagcagcc atttctttca cgatttcttc agtgaatgct ccaggttggg
    23461 tagaagtacc aatcatgatt gtcggatgga tcgcttttac aactgcttct aagtttgtca
    23521 attcatcagc attagtgaaa tctgagcgtt tgcgagcgaa tgggatttga ccaggagtca
    23581 atccttctgt atcttcaaac aataaacctt gtttatctac ttgatagaaa tgttggcgtg
    23641 cttcttcttc aggtacacct tgacggatca tctcatctaa aaggatgttt gcgataccca
    23701 caccagcagt accagcacca aatgtcaaaa ttatttgatc tttcaattgt tcaccggata
    23761 tattcaatcc gcctaataca cctgctagga caacaattcc tgtaccttgg atatcgtcgt
    23821 tgaaagtagt gatttgatct tcgtattttt ctaagatcgc tgcagcattt cctcgtccaa
    23881 aatcttccca atgcaataac aattctggga ataattcggt agctgattga acgaattgat
    23941 cgatgaattc atagtaagtt tcgccttcta cacgagcatg acgattgcct aagtataagg
    24001 gattattcaa taattcttca ttattagtac cagcgtcgat cgatacaggc aaaacttgtg
    24061 ctggattaat accagcagca gcagtataga ccatcaattt gccgatagcg atgtcaacac
    24121 cgttcacacc ccagtcgccc atacctaaga ttccttctgc atcagtcaca acaatcaaac
    24181 gaatgtctcg tccatctgcc gcgttcttca aacttgcttt gatgttttct ggttcgtcga
    24241 ttgaaagaaa tgcagcatct tgcggtttca agaaaatttc gttgtattgt tcgattgaat
    24301 ccgcaacgac aggatcataa acgacaggca tgaattcaac taaatgttcg cccatcaatt
    24361 tataaaacaa tgtccgattc gtattgaata gattcattaa gaagatacgt ttttccaaat
    24421 ctgtttgttt gcttaagtat tgaccataag cttgaacaga ttgttgttcc agtgtttgga
    24481 cagtacttgg aagcatacca gtgattccat attttgcccg ttcttctttt gtaaaagctg
    24541 ttcctttatt tagaaaagga ttatttaata agtttaaccc tgtaagcatg aatgattcct
    24601 cctaagtttt aatacaaacg aagtatagaa gtcagatgat gatatagtca aaaagagcag
    24661 gtatgataaa ttttatttat atgtaatata gccaaaagaa atcaaaatag cagtatttgt
    24721 tctttttata tcgacaatcc ttgcttgaat actatgcgta tctcttatat gctagagaaa
    24781 gaaaagtaga agaataaggg atagatggaa tggataaata ggatttctga ggaaaaaagc
    24841 acatgatagc gttgatagga gtcacctatg tcaggtgata aaaatacata agtagaaaat
    24901 taagaggagg aagagaaaat gaaagaagtt caattgatta gaaaaagcga actatcagaa
    24961 ggcggttgca atgcatgtgg cgtagtagaa gcgacaagct atacattaaa attagattcc
    25021 aatcaagcaa taatctctga actgacagta ggcggtcttg tggacagtct ggcgcttgct
    25081 gaaggtttta ctggagaaga tatttatgag atgttttcag aagtccgtca gttaaaaaaa
    25141 ggagaaaaat gcatagaggt tcatcatgag agcccgaatg tgaggttcaa acgtggtgat
    25201 aatgagatga tcttcaagaa tcatgtgtct gatcacactg aactatatga aatcgtgaat
    25261 caaatactgt ctgggatttt tgaattagga ccttatgagt tcaaggaaga aaacggtaat
    25321 ccaaaattaa atgaagaatg gcaagaaacg attgaaacac aaagaaacaa tccacactta
    25381 tttcaatagt cttccacagt atttcgtaaa aatgttgatg aaaaagaaac accgtgaatc
    25441 agaggtcgtg aaaaacctgc cctgcatcaa gtaataagaa cagccaaaca aaaatagctc
    25501 ctcctatttt tcgtttggtt gggcttatta ccgcagatgc aagtttttga acaccgttta
    25561 aggaagagac tgtgaagtca acgttctgac ctgagtatta gagagacaaa tggcaaaata
    25621 gttcctcata ttttgccatt ttttgagcta ataccgaggg tcagctgatt gaacaccgtt
    25681 ttatcgagag gttgtgaaaa agtcgcttag tttcgagtag taagaaaaat tttgtgaaaa
    25741 tggctttcca catttttgca taaatttgac ttaataccga gaaaatggct tttgaacacc
    25801 gtttattcaa aaaaagggac tttgacacta cttttgtcaa agtcccatcg gttttttatc
    25861 tatttttatt acaatcattt cttccagagt agtgacatct ggaatggctg aaatgtaaac
    25921 agattatttg cctgtatcaa tgtcgaagag taatataaaa agtgtaaacg ctatcatatt
    25981 gttcatcatt caaattttat agagagaagg cattgagatg gaaaaaacat atcaagcagg
    26041 tacaaatgaa ggaatagtag attttatcaa tatggaagat ttagaaatcg cggcttcaca
    26101 agtgattcca gctggtggtt atggttacat cagcagtggt gctggcgact tatttactta
    26161 tcaagaaaat gaacgggcat tcaatcatcg tttgattatt cctcatgtat taagagatgt
    26221 agaattaccc gatacaacta cacattttga cgaagaaatg ctgactgcac caatcatcat
    26281 ggcaccagtt gctgctcatg gattagctca tgtgaaggcg gagaaagctt ctgcaaaagg
    26341 tgtagcagat tttgggacga tctatacagc aagttcttac gcttcttgta ctttagaaga
    26401 gataagagaa gcaggcgggg agaaagcacc gcaatggttt caattttata tgagcaaaga
    26461 taatggaatc aatttggata ttcttgaagt ggccaagcgt aatggagcaa aagcaatcgt
    26521 attgacagcg gatgcaacag ttggcggaaa ccgtgaaaca gaccgcagaa acgggtttac
    26581 cttcccgctg ccaatgccga tcgttcaggc ttatcaatca ggagtaggcc aaacgatgga
    26641 tgctgtatat aaatcttcca aacaaaaact tagtccaaaa gatgtagaat ttatcgctgc
    26701 tcattctgat ttgccagtct acgtgaaagg tgttcaatca gaagaagatg tctatcgatc
    26761 attagaatct ggtgctggtg gaatttgggt atctaaccat ggtggccgtc aattagatgg
    26821 ggggcctgct gcgtttgatt cgttgcaata tgtggcagaa gcagtagata aacgtgtacc
    26881 aatcgtgttt gacagcggtg tacgacgtgg acaacatgtt ttcaaagcaa tcgcatcagg
    26941 tgccgatctt gttgctattg gcagacccgt tatttatgga ttgtctttag gaggaagtac
    27001 aggagtccat caagtgtttg atttctttaa aacagaattg gaaatggtca tgcaattagc
    27061 tggaacacaa acagtagaag atatcaaaaa aataaaattg cgtgagaatc gttttattta
    27121 agaaataaat gacgaaaaaa ataggagtgc ggcagatgat gccgtactcc tatttttata
    27181 gttcaaggat gtcactaata gaataatttg aaacgaaaaa ataaaattga aatatttttt
    27241 catacttaat aaaaaaggaa gaatattcat gtaaacgatt ttattgtttt tttctctttt
    27301 atacaaaaag ggtcataatt tcaagtaagc ggatgaattc atgaggattt tttgcatact
    27361 gtctctacta tacttaggtc actaagaaaa aggagtgatt tattatgaaa aagaacatga
    27421 ttgggacatt attactttca acacttcttc taggcggctt ggcaacacca gcttttgctg
    27481 agggtcaagc gacttcaaaa ggagatatta cctttactga accaacaaat accgttgagc
    27541 ctcttaaccc tactgatcct tcaaaaccag tagagccagc agatccggaa aatccagcaa
    27601 ctggccagac aggttcttta acattggatg tagttcctga attgccattt ggtacacacg
    27661 agattgaaag cggaacaaaa acgtatcaag tagacgcttc aaaaaacgat acaccttatc
    27721 tccaagtatc agatcgtcga ggtgtaggtg cagatggcca agcacaaggg tggaacgtga
    27781 cagtttcggt ttcagatttt gtaaacggtt cacaagtttt gcaaggcgct gaattagatt
    27841 ttggaacatc cactgttaaa agtacgtcag ataacgaatc cactggacca actagtcaaa
    27901 ctgtaactgg gttgagtaaa gcaagtgcag cgacaccaat atttacagca gcaaaagatc
    27961 aaggtctggg aacatggctt tctgtttatg atccagcaaa tatcacactg aaagtgccga
    28021 aagcagcagc tggaacattc acggctgatt tgacttggaa cctcgtggct ggcccagtag
    28081 catagagtat gaaataaatt caacaaactg cggtgaaaat actataggtg aaggattttt
    28141 taccgcagtt gttgttgaaa ggatgtggtg gacaatgaat caaagtaaac gactgtttgt
    28201 ttcgtttttt tctattttaa gtctattttt catttttccg tcaatcagcc aagcaaagga
    28261 ttcagcagga gactttggaa tcaaaccggt atttccagag aaccaaatag ataaagcaat
    28321 cggttatttt gatttattag tggcaccgga acaaaatcag acactagaag taattatcag
    28381 caattcttca gatgaagaac gaacatttga ggtctctgtc aatccggcgg taacgagtga
    28441 tggtggaacg atcgattata gtcaaaaaaa cccaacgtta gatgagacat tgccgtttga
    28501 tgtccgtgac gttttgctca ttgcgaaaaa ggaaatcaat gtatcagcac atgcagaaac
    28561 aactatacct atagaagtga aaatcccagc aaaaagcttt aagggacgtg tattagcggg
    28621 tattcatgtt tcacctaaag aagaagctga aacagaaaat gctacagaag gagcacaaat
    28681 caaaaatcgt attgcttata atctcgcagt cgttttacaa gaaagtcaag agacgataga
    28741 accggatctg aaacttttat caggagattt ggacgaggtc aacgcaaagc caactgttca
    28801 gcttcgtttc caaaatcctc agcctaggat tatcagcaat ttgatattta cgagcaagat
    28861 cttttatgaa aatcagcttt atattgaaaa tacgtctaat gaatttttag ttgcaccaaa
    28921 ttcgaatttt cacttgaatc ttgatttagc tggtgataaa gcaaaagccg gcgattaccg
    28981 cgcagaaatc atagcaaaat caggcgacag taatgaatgg cgatttacac aaaactttac
    29041 gatcaaaaaa gaaaaagcac aaaaagtaaa tgaaaattcc gtttttgcag tacaagaaca
    29101 atctttccca tggctttatg caggattggt tgctgcagtt ctagtgttat ggttgatttt
    29161 gctgtttttg tgggtccaca agaaaaagaa aaaaggagaa acaacatgat gaggtgattt
    29221 cgttgaaaac atcgatctta ttgggaggga ttattgcaag tttgctgttc ttcagctggc
    29281 aagagccagt ccaagcagat accaaaagtt caggtacgat tacattttat gatctaagtc
    29341 cagttccgca tccaagtggt tcagtcaatg gcgcatcaaa acagcagaca cagctaccga
    29401 tttataaaga atctaatcaa catggcgtat tcccggagac gaatgaagaa aagatccgtt
    29461 ttctttattt gatcattggt atagaattat ggcttcttgc gtggttgttg ttatggagaa
    29521 gaaaggaaaa ggaggatgaa catgttgcta caaaataaat tttcattttt tcgctccttc
    29581 ttttttactt cgctttttgt tttaagtata tttatctttt caccttcggc agaagctgtt
    29641 ggagcaacgc ctcctgccat ttcttatgat ccatacacgt atgaaaatat cgtacctcca
    29701 aatggtggac gtagtgcagt caatggcggg aagcttgtcc aactaactgg ggctaaccaa
    29761 ttgcctaaat tgactgctac ttatttgaac gatggttcaa atgatccttg gaaaggtggc
    29821 acggtccgtt ttcattggga aagccatgtg aaactaacaa atgtacttga tttggtgaat
    29881 atcactgcac aaggatttgc atttgtggcg atcatcaatt tgccggaaca tgtatcaagc
    29941 agtgatgtat taaaagcaat tgactggaac aacgcctact tgtatattgc cggtgccccc
    30001 atcaaggtta ctagcggtag tttattatca gcaggaagcc ataccttgcg ttttgggatg
    30061 gggtcgtggg atacaaatac tctattggca gatattattg ctattattac gcgaggcgaa
    30121 ttcaacgtgg acgatatccc gcttcaattt gatgttacag ctaatgtcgc gaagatgaca
    30181 gaaaacggag ataaatatga tacgagtcca aacaaaattt tgaccaaggg taaattacaa
    30241 ccttctatgt ctaaaaaggc cgttttttct gttgattttt atgattcgaa taatattatc
    30301 caagatcgta tgttcaattc gattttagct ccagctgcag gtagatttta tcctaaatta
    30361 actggcggaa acttgaatcc aggagcatat gcattttctg caagtgcaga gataaatacg
    30421 tggaatagtt acatctcaac aagtgattca acaggaaaat ataatacatt tgctgatacc
    30481 acagaatacg tggatggaaa taaccagaac cttccaggct ctaccaatag tcggacattg
    30541 acgatggggc tgactgaagg acgttttgat cagttgccat ttagtcgctt tgatcgcgta
    30601 gtcaactatt ttacaggaaa aaacgttaca caaggagcaa tactgactca tactccagca
    30661 agcacaagtg gattgaatca gacagccaat atcgtgtaca gtgggaaaga tgcgcaaggc
    30721 ggattgcttt ctcctgttgc tttaaaggta ttggagcagt acaagctaga cggaacggtt
    30781 ttaccaacaa acttaacagc cgatagtcag tggggaaagc tcctttcttc tgcatcgtac
    30841 caagtcacgg ccaattggtc agcaactgaa ctaaaaaagg gttcgatcca ttacaggctt
    30901 tattcgaaag gaacctaaaa attagcgaca ggatggacag atcaactttt ccaaacgatc
    30961 caatcaaata acgggggtgt aaatacagct acttctacac tacctgcatt ggcttcaggg
    31021 caatattatt ttgattatcg cttggtggac gatgtactta ctaacatgta tccgtctttt
    31081 gcgtacaaat ggcagtctga acaagctgga atcaccactc ttcctcaaat aacagtggct
    31141 aattttccat ctgtgagtgc agatagtcag ctaaaaaacc ttagcagaca acctgagaca
    31201 ggagatcccc tgtctgctct atcaggagat acgattcaag aaaatgtgac attcacgtta
    31261 acaaaatctg gggatgcgat aaccgacaaa aaaatcacga tctcacttcc tgaaaatact
    31321 acttatatca atggttcctt aaaattaaat ggtacaacta tcgcagatac cggcattcaa
    31381 caaggagttt ctgtcccagc agatctattg agcaaaatag gagataccat tcatcttact
    31441 tacaactatc aattaaatac tgtagatact tctgtacaat ccgtcagcat actgacaaag
    31501 gcagctgtac tttccagcaa tattacatta gcagatggtg ctaagcttcc taacccagtt
    31561 gtccaaacat ctgctaaaac aattcttgtc cccaaacaag aattaacatt agttaatgta
    31621 ccagatgatt ttacatttgg taacgatctc cccaaaccgt tgaagacaag ttattatgaa
    31681 gcaaaaggcg atttttcttt tgatgtgcgg gatactcggc ttccaagcac gtctccttgg
    31741 caactgacag ggacattgac ttctttattt aagaatgatc aaggtcaaga attaagcgga
    31801 acaaaattat acttcaatca ttctggatca aaacaattga ttcagcaagg tcaaaacacg
    31861 ttgatttatg agagtgatgg aacagctaaa ggagaggttc tcgttgactt tcccgatacc
    31921 gatggtttac tcttagaggt aaatagcagt acgaatgctc aacctggcgc aacgtatcaa
    31981 ggcatggtca catgggaact gacagctggg ccaaccagct aagtgattag aatttgtatg
    32041 gatctgtgat aactgtcaca gatcctcttt ttcaaggatg agaaggaaac ttctgctgtt
    32101 aaaatcagaa atgcttggag gagtggactt ggaacttttc agtttgcttg aaaaaaatga
    32161 acaacggcaa atcaaacttt tccaactttt attagaggaa aaaggagaga tttccgttaa
    32221 taacgtactt acccgcttat cagttgatcg ggctaccttg aaagaagatc tgttttattt
    32281 acaagctaac ttggaaaata tcaaacaatt ggaaattgtt atccaagaag ggaatatttt
    32341 attaatcaga catggaaata tagcagcagt cgatgtttat tatcattgct acttgcgcta
    32401 ttctacaaaa tatcagatac ttctttatct gttggaaaat ggctcatttg atcggcagaa
    32461 acttgtcatg gaacttaata tcagttcggc tactttgtct cgcagagtga aggaattaaa
    32521 tgattcttta aatgagtttc atctgaaaat aaaaagcggg cggctgaccg gtccagaaag
    32581 tcaaatttgt tatttttatt tccaattatt ttggtttgga cgtccttatc ttgaaaacaa
    32641 aaaagaatac agtgatttat caggaaacac ttttttagat ctgctgcaaa aagagtttag
    32701 ttttactatt acagaagaag gacgattgaa atttgaaata tggctttcca ttatgaagaa
    32761 gcgaatgcgc tgtacgaaaa aatccaaacc agattatagc aatcttcctg ttggattgtt
    32821 tcaaacgaca caatttttat tggacctcca tacatttttg acccgttact tctttcaata
    32881 tgcctttcct tggaatcaaa atgaaacgtt ggttttttat cttttcatga tcagtaactt
    32941 tacattagat acacataact cgcatgtcca ggagtttttg ataagcgaaa aatacaaaga
    33001 cgacgtagta gctcaattga atcgaacgtt taaacaatcg atagaagaat atttctcttt
    33061 ttatgttttt ccagaagaga tttcgcaaaa gattgcgttg acagtgatgc aaaatcacgc
    33121 tcattttgcc tattttagag gatggatgaa tatttttggc caagaaggat taaaacagcg
    33181 gttaactgaa gtagaagata aacaattcct ggttttatgt gaaagattgg tcagacaaac
    33241 atttgctatt gttgatttta ctgaagtaga cgaggaaaat gcccgctttg aattatttgc
    33301 tcgctatgca tctattttgc ggacgctgat caagcagtta gaattacgtc tgcaaattgc
    33361 ttatgatctt ccttatgaaa ggctaatggc ggatatcgtg aaagaaatca tccaggaaca
    33421 attgctgaat acgatcaaat atgatttagt cgaatacgag aaagaaaagc agtatgatat
    33481 cattttgact agccaattga aagagtaccc gtcacagaag tccgctaaag tttttgtatt
    33541 cactagcaac gaatataatt atgatttccc ctatttgaac caatttttaa aagaatgtta
    33601 tttagaaaaa ttgaatttaa ggatgaataa aacatgaaaa tcgtgatcat tggtgcttcc
    33661 catgcaggca tcacagctgc cctaaatcta agaaaacttc aaccgaaagc agaagtttta
    33721 ctgatcgatg aagatcataa agatggacta ggctatgttt caaatggaat caacctttat
    33781 ttaaaaggaa agatacgtag tttagctgaa gttgcccata acatgcggac tcttcaagaa
    33841 agtggggcaa aactgatcac cgaatggaga gtaactgaac ttgatccaga caaacatcag
    33901 ctcatcctcg catccaaaga aggaaaaaac gagaccataa cctatgataa attaatcgta
    33961 gcaacaggtt cctctcctgt caccttgtat aaacaaattg aagctgaaaa tgtctacacc
    34021 tataaaaatc tagtgcaatc taagcaagta cttgccgctt taaaagaagc aaaagaagta
    34081 gtgatcttcg gtgctggtta tattggattg gaattagcag atgctttgag aaataaagga
    34141 tacattattc atctagttga ttatatgccg aatgttttat caagatattt cgataaggat
    34201 atgatcaaca gttttcaaaa tcagctgcaa actaagcaaa tcaattttta tccaaatgaa
    34261 ttcttgatcg attggaaaaa atcagaagag aaagtagtat ccgtacaact tctatctcaa
    34321 gcaataaagg cagatatggt cattttttct gcccaaactc gtcctaatac gacattgtta
    34381 aaagaaaaag tggctttgta tgaggatgag actgtgatag tcaatgaata tctgcagaca
    34441 agtgatccgg acatctatgc gattggagat atcgtcccag tcagttttga caaaaataaa
    34501 cggcatctct ttttaccttt agttactcga gctgtacata tggcaagagc agtagcgcta
    34561 actttgagtg gtcagccaac cgcttacgac ctcagacaaa agataacagc agcagtcatt
    34621 atagactact ttttaggaac tgtagggctg acagaagatg aagcgccatt cttggaacaa
    34681 aataccggtt cgtgttcagg agaatttgat ctatttccac aatacgatga agaaaacaaa
    34741 acagtaaatg caaagctgat ctaccatccg gatacattag aaataattgg cggacagctg
    34801 ataagccaag aattcttatt atcagatttg aacctgcttg cggatatcgt gaaacacaaa
    34861 actacgattc cacagctagc agttgaggat tttggatttc tgtctgaaca cacctctcgt
    34921 tttcactacc tcaatgagtt agcttttaaa gtactagcta agagagcaaa tagcaataga
    34981 gtagataaaa gactgtgaga aatatcacgg tcttttattg tgtggggata taataaatat
    35041 taatcaatcg agaataaaaa attcatataa tgaaatagcg gaagaatttt ttgagcataa
    35101 tattcgccaa aaatttatca agtgataaaa ttgttgtata aaatgattat ttcaggagga
    35161 ggagttaaat gtttttagca ttaaatgaaa ttatgcattc aaagttacgt tatgcgttag
    35221 ttgcaggggt gatgtttttg atcgcctacc tggtattttt tttgactggg ttagcttatg
    35281 gcttagctca agataatcga acagcagtcg acaagtggga ggcagattcg attgtgcttt
    35341 cgaaagatgc aaattcaaat ctagggatgt ccatgattac taagaagata gcagaagaag
    35401 tcgaaggtgg gaaagtggcg tatcttgccc agacacctgg agtcgtgact agtaaagaca
    35461 gtacagaaga aggaaaaatc aatgttagct tcttcggtat cgataaaaat caattcatca
    35521 tgcccaatct tgttgaagga aaagcttttg ataacgatga tgaggcagta ggcgatatta
    35581 gtttgaaaga agaatatggt ctagccgtag gagatacagt taagttatct ggtagtgaca
    35641 agacgtttaa actaactggc tttacggatc atgccaaatt caatgtctca ccagttctct
    35701 atacaaccat caatgcttac caagagatcc gcttcgaaaa agaagataca agtgaaaatg
    35761 cacggattaa cgcaatagtt gtcagaggta aaatcagtaa tttacctgaa gatttagaac
    35821 agatcaaaat ttctaaattc atcaatgaat tacctggata taatgcgcaa gtattgactt
    35881 ttggatttat gatcggattt ttgatcgtta ttgcggctat tgtgatcggg attttcattt
    35941 atgtactgac gatgcaaaag attaatatct ttggtgtaat gaaagcacaa gggatcacag
    36001 gaggatttat tgcgcgttct gtagtggcac aaacattcat tttatcattt gttggtattc
    36061 ttcttggtct attaggaaca gtgggaacat cccttgttct acctgatgcg gttccattcc
    36121 aaagcaattg gctgtttttt ggcgtcatta gcttgttgat gctggtagta gctgtgttag
    36181 gcgcactatt ttctgttcgg acaatcgtaa aaatcgatcc gttgaaggca attggataag
    36241 aaggaggaag agcatgaaag caatagaatt taaagaagta gaaaaaagtt tccaagatgg
    36301 cgaccaagta gttaaagcat tgaaagaaac aaccatgagt atcgataaag gggaatttgt
    36361 tgcaatcatc ggtccttctg gttcaggtaa aagtactttt ttgactttgg caggcggatt
    36421 gcagacgcct agcagtggct ctgtatttat caatgatcaa gaattcagta atcaaaaaga
    36481 aagtgaacgc gttaaactac gttttaaaga aattggcttt attttgcaag cttccaatct
    36541 ggttcctttt ctgacagtaa aaaagcagtt attattagta gataagatca aacatgaaca
    36601 tcgtcaaaaa gaagcaaaag aattatttga gcagcttggc gtggataagt tgatcaacaa
    36661 gtatccagaa gaactatctg gtggagaacg gcaaagggtc gcaatcgctc gtgcattgta
    36721 caatgatccg tccattattc tagcagatga accaactgct agtttggatt cagaaaaggc
    36781 acgagaagta gtcgatatct tggcaaaaga atcaaaagac aaaaataaag caacgatcat
    36841 ggttactcac gatacacggc tgattgacaa atgcgataga atatttatga tggaagatgg
    36901 tgtattgaaa gaaaaagaat aaccaaaaag caggtggaaa aatggtccat cgatacaaca
    36961 aagatacaca gcaaaaaatt ttgaaagaag cgactgactt gtttatgtcc aagggatatc
    37021 tcggcacttc aacaagagag atcgcacaaa aagttgggat cacccaaccc aatctctatc
    37081 attatttcgg tgataaagaa aaactatata cggcagtttt agaaaaccac ttaaaagatg
    37141 ttggaaaagc tttgagagaa atcgttcaaa caagcgaaac gggatttcaa gtaaccttga
    37201 caaaaatggc gcagtttttg attgagacac atctggtcga tttgtttctg atgcttcacg
    37261 atcttgaaag caatctttca aaggaaacaa gagatcatct tttctttcta tggaagaaaa
    37321 attatcgtga accttttgaa gaaatctttt cagcaaacca atctgtgcta agaaatggga
    37381 tttcaaaaga aatcgcagca aggcattttt tcttagtgtt agcaccttac atcactcggt
    37441 cgaaaagacc tgtggaagaa ccgctaaatg tggcgcaatt gatcgattta tatttgaatg
    37501 gtgtattagg agaagcgtaa agctgttata tagggagaaa aatagttagg tgaagaagca
    37561 agatatgacg aagatcgtta tatcttgttt tttttatata ggtagttttt cataaataca
    37621 aatttgttat tctctcatga ttatcagggt atatttttat ttattatgtc ggtgttccag
    37681 gaagtgtttt aatttaataa cgaagaaatt aattgtttgt agaatgaagg aaactattta
    37741 ttgggtagat gaatcaccac gaatagtcaa aaggagattt caggatatgc caaaaatgaa
    37801 aaaaatcatt ttagcagtaa tgttattttc tacggttata tcttttacag cccctttttt
    37861 gcgtacttaa gctgatttta agttttgacc cttagtctgg atctacgagg tgagagtcaa
    37921 gaatgaaaaa aataattgga gcttttgtat ttgcaatcat tatcattatt atctgttttc
    37981 aaatagatgt ttttggtcaa aaaaagatag ttggacaaac ggtcagcagt acgaacagta
    38041 cggttacaaa gacaaaggaa tcatttgatg atacagaaca agagacatta atcaaaatcg
    38101 gaaaaaatga ccgtacacta tatacagatg actcgctaac taccccactt gcaactataa
    38161 acggcggaga gctggcggag tttctttctg aaacaaaaaa tgcttatcag atcaagacaa
    38221 atgatggcta tactggatat ttagccctcg aagatggaac caaagtcaca aagaatatac
    38281 aaacaaaacc ggaagagcta tctgatgcag tgattgtatt agatcctggg catggcggaa
    38341 atgatactgg ggcattaagc aatgatgaac aaacagaaga aaaagatata acattaagta
    38401 cagccataaa agtaaaaaag gcgctagagg atgctggagc aacggtttat ttgacccata
    38461 ctacagatga attagtacag cttggagata tatgcgacta cagtgaagaa aaaaaggcag
    38521 atgtctttat cagtttacac gcagactcta cggaatatgc gaatgaagca actggaatca
    38581 cgacatatta ttactatgga caagaggaaa cattagcaca gacaattgct gactccttca
    38641 ctgatctgcc tctggattca agaggaatct ccactgggaa ctatcaagtt cttcgagaaa
    38701 atcttcaacc ttctatttta atcgagatgg gttatatgaa taatgatagt gatttaaagg
    38761 aattagtaac agacagttat cagcagcaga ttgctgcaag tttgacacaa gcattgacca
    38821 cttattttca gtaataaata agcccagcca aacaaaaata gctcctcata tttttcgttt
    38881 ggccgggctt attatcgcag atgcaagctt ttgaacaccg tttaaggaag aggttgtgag
    38941 cctgccgttt aactccgcgt cacaaggagc aatttcaaaa aacagcttct catgtttgat
    39001 gactattgtg acttgtgacc gaggagttgg catgagaaca ccgtttattc ggaacaaggg
    39061 actgtgacat gacttttgtc acagttccat tattttttta gcagcttcaa agctttttct
    39121 gtattggcaa aatgaagttt ggcatatttt tcaagcatag gcatgccgcc tttctccaat
    39181 agttttgccg ctacttggtc agatttcgtt ccagctcctg atggaagggt gattccagct
    39241 tcagctgatg ctttgtgtaa ctcttccaaa aagctggcac gactgatgat agaagcagca
    39301 gcaacagcta aatgatattg ttctccttta gtaacgaagt acagtttttc ttgtaattga
    39361 tttttttcta aacgcgcata ttttttaaaa tttgcttccg gcgtaaactg atcgatcaaa
    39421 atcgcttctg gtttttctgg ctcgattttt tttagcagca aatggatcgc ttgattgtgc
    39481 aaagcgactt tcatccgaac ggcattgtat tttggttgga tctcattgta tttttctgga
    39541 gataagacaa gcagtttata ggggatggtt ttttttaaga tgtcagcaag ctggatgatt
    39601 tggctatctt ttaactcttt tgaatctcta acaccaagtt tacgtaattc tgcaagctga
    39661 tcacgtttca cataagcagc acatactgtt agcggaccaa aatagctgcc atttccgacc
    39721 tcatcactac ctaaaacgga taattgactg atattttttg gcaaagaaga ggctgttttt
    39781 gctggcttgg cttgtttatc ctgtgcctcc ccccatttat cagcttctat tgctgcattc
    39841 gtaccttgaa acatcacttt tccggatgta taagcggtaa tggtcgtccc gtcttttttt
    39901 gcagcaaagc tagtataagg aatctgttta tttaacaaat aagagcgata gtatgctttc
    39961 atttgactaa gttggtcgtt tgttgctttg ataatgacgt tgctcataaa attctcctcg
    40021 tttttataca taaaactata ccgcaactca cgacttttcg ttttctaaga gattgcgaga
    40081 catagcattt ttttaaagtt tatcatataa tagttaagta tgtgaaaaat atttgtggag
    40141 aacggtgaaa gaaccaactt catggtacac taaataaaac tttcatcaaa taggaggaaa
    40201 tgattcgtat ggcgcacgaa aaaacacgct acaaagcagt gattgccaac caaacatata
    40261 ctattatcgg acgggaaacc aagcatcata tggatatcgt aacgaagctg atcaatgaac
    40321 agttagcaga attgaaacaa ttatcaccac aaatggataa tgaacaagca gcaatcttga
    40381 tggctgtcaa tgcgctttcg gatcaattga agaaacaaga aagaatcttg gagctggaag
    40441 aagaaacagc agaattaaag aaaaaaatga tcaaatttac agagcttgaa aatcgtgtga
    40501 aacgcattga agcaatcgag aacgaagctc gggaagtatt gaaagaaaat ggtcaagcag
    40561 atcataccat taaaaatcat gtggaagcac aacagatttt aaacgagaaa cgaaaaggac
    40621 aaattaaaca aaaatcttct aattaagatc cttttatcaa aataagaaaa atttaaaaaa
    40681 gttagaagag aaaggaacgt agcatgctga gtttgctgat tttattttta ttgctaattg
    40741 cgtttttttc tggagcacgt cgcgggtttg ctttgcaaat catattcgcg attggatatg
    40801 tattgtcatt tattgctgcc cagcattttt acaaaccatt agcaagtcat ttggaattat
    40861 acattccata cccagctgtc accccaacat caaagttagc attttttgat caggtatttg
    40921 cttttcacct agatgaagct ttttatgcag gaactgcttt tctgattatt ttgctaattg
    40981 gctggctgct tacccgattt gtgggggttt ttgtccatgg attgacgtat gtgccgatct
    41041 tgagacaggt agactggatt gcaggaggca tcctgtcact aatcatggct tacgttacta
    41101 tatttttgat tttgcagtta cttgcctttg ttccattaga tgtggtccaa aatcaattcg
    41161 gcgagcatag tttcgctcgt tttatcgttg agagaacgcc atttcttacc aacaagatgt
    41221 atgagctttg gtaacgaata ttttgaatta aggaaaatag tgctggaaaa tatttcgttt
    41281 tttgtacaga gtagtttatt taagaaggct gcgtagcgta tgtccggcac agctcttttt
    41341 tcatagtgaa agataaggtg ataaaatgaa taaccgaatc cttgaaacat tggaatttga
    41401 aaaagtcaaa cagatggtca gacaatttgt agtgactgca caaggaaaag aagaactggc
    41461 agaattggta ccagtgagtg agaaacaaac gatcacaaac tggcttcaag aaactgagga
    41521 tggattgaaa gtgcaacgtc tgcgaggcgg gatccctata cctaaacttg aaaatatccg
    41581 tccccatatg aaacggatcg agatcggagc agacttgaat ggagtggagc ttgcacaagt
    41641 ttccagagta ttgtctacga caagcgaatt gaatcgtttc attgatgatc tttctgacag
    41701 tgaaatcgaa tttgcacgtt tgtatatgtg ggcagatcag ttagtcacga tccctgtttt
    41761 gagccgccgt ttaaaggaag caatcgatga agacggacgc gtgactgatg acgcttctcc
    41821 tgagttaaag agcataagac agaacattcg gcgaagtgaa caagctgttc gtgaacagtt
    41881 agatgggatc gtccgtggga aaaatgcaaa gtatttaagt gatgcgatca tcaccatgcg
    41941 aaatgaccgc tacgttatcc cagtcaaaca agaataccgc ggtgtatttg gcggtgtagt
    42001 ccacgatcaa agtgcttcag gacagacttt atttattgaa ccaaaacaag tggtggattt
    42061 gaataatcgt ttgcgtcaat accaaatcgc tgaacgaaat gagattcaac gtattttaag
    42121 tgaactttct gctgaacttg ttccccatcg tcaagaaatc atccacaatg cttatgtgat
    42181 tggtaaaatg gatctgatga atgcaaaagc acgatttggt aaagaagtaa aagccatcgt
    42241 gccgggaatc agtgaagaca atcatgtcgt cttgaaacaa gcaagacatc cactgatcga
    42301 tcaggaaaaa gtagtttcta atgacatcac aatcggaaaa gactatcaag ccatcgtcat
    42361 tacaggacct aacacaggtg ggaaaacgat cacgttgaag actttaggtc tgttacaact
    42421 gatggggcaa gcaggattac cgattcctgc aggtgaagaa agtcaaatcg gtatttttga
    42481 ggaagtattt gcggatatag gagacgaaca gtcgattgag caaagtctat cgaccttttc
    42541 ttctcatatg acgaacactg tagatatttt atcaaaagtc aatgaaaaaa gtctggtatt
    42601 atttgacgag ctcggtgcag gaacagatcc gcaagaaggt gctgctctag caatcgcaat
    42661 cttagatgat cttggtaaaa agtctgctta tgtgatggca acaacgcatt atcctgaatt
    42721 gaaagtttat ggatacaatc gggcaaatac gattaatgcc agcatggagt tcgatgtgga
    42781 tacactaagt ccaacgtatc gtttgctgat tggcgttcct ggacgaagca atgcgtttga
    42841 aatctctagc cgattaggtc ttgatacaga agttattgat gaagcgaagc agttgatgaa
    42901 tgatgagagc caagatttaa acgaaatgat cacagattta gagaatcgcc ggaaaatggc
    42961 agagaccgaa tatctggaaa tgcgtcattt tgtttctgag gcacaagaac ttcacgatga
    43021 tttgaaagaa gcttacagct atttctttga agaacgtgaa aaagaaatgg aaaaagcaaa
    43081 gaaaaaagca aacgaagtcg tgtcagaggc ggaagaaaaa gcagaaaaaa tcattgctga
    43141 tattcgtaaa atgcaacagc agattgggca aggaaatgtg aaagagcatc agttgatcga
    43201 tgcaaagacc caattagcaa atctacatca agaagaaact ttgaagaaaa ataaagtatt
    43261 gaagaaggcg aaagaacaaa aaacgttgaa accgggagac gaagtgttgg ttacgactta
    43321 cggccaaaga gggacgcttt tacgtaaaaa cgggaatcag tggcaagtag aaatcggtat
    43381 attaaaaatg aatgtgtccg aagacgagct gacgcctgtt gctcctcaaa aagagccgac
    43441 acaacgagtt atccatgctg tacgatctga atctagtagt cacgtgccga atcaattgga
    43501 ccttcgagga aaacgatacg aagaagcgct aagtgaggta gatcaatatt tggattctgc
    43561 cattctagct ggttatcctc aagtgactat tgtccacgga aaaggaacag gcgcacttcg
    43621 caagggaatt actgattatc ttaaaaacca tcggagcgtc aaaagctttg agtttgcacc
    43681 ggcaaaccaa ggcggaaatg gtgcgacaat tgttaaattt aagtaaagct tactaaaggt
    43741 aagcagatgg ttcgctatcc aagtatagaa atgctatact aatcatagat tttaaaaatg
    43801 gaggtctttg atatgtcaca agtaattaca gataagacat ttaatgaaga aacagataaa
    43861 ggacttgtat tgattgattt ttgggcaact tggtgtggtc catgtcgtat gcaagcaccg
    43921 attttggatc agttggaaca agaatatgat gaagaagaat tcagaattgc taaaatggat
    43981 gtggatgaaa atccagaaac tcctcaacaa ttcggtatca tgagcattcc aacattaatg
    44041 ttgaaaaaag atggtcaagt agtagaaaaa gctgttggtg ttcattcaaa agaacaacta
    44101 cgtcaaatga tcgatcaata tttataaaaa cttacagcaa aaataagctg agggtgggac
    44161 tgaatccagt tccgtcctcg gtttttttgc ggttgagtta aggttattca aattaatatt
    44221 ttttgagtat aattacgttg tcaggctgga ttgttttttt gacagacatg ctataataac
    44281 tttaattgaa tatgaagggg agtaccagat gaacgaacga atcaaaaaca aattagcttt
    44341 acttcctgat cagcccggct gttacttgat gaaagataaa aatggaacga tcatttatgt
    44401 cggcaaagcc aaaatattaa aaaatcgtgt ccgctcatat tttactggca gccataatac
    44461 gaaaacggaa cggcttgtta gtgaaatcga agactttgaa tacatcgtta cagaatcgaa
    44521 tatcgaagca ttgctcttag agatcaatct gataaagaaa aatgatccta aatacaacat
    44581 tatgttaaag gatgataaaa cctatccttt ccttaagata acgaatgaaa aatatccccg
    44641 tttggtgatt actcgtaaag tactaaaaga caaagcactg tattttggac catatcccga
    44701 tgtcggtgcg gcgaatgaga caaagaagat cctcgatcga ttatttcctc tgagaaaatg
    44761 caaacctagt cagacgaagg agccttgtct ttactatcat ttgggacaat gtctgtgtcc
    44821 ttattatttc gacgtagatc cgaaagtcta tacgaaaatc gttgatgaag tgaaaaagtt
    44881 tttaaacgga ggacacgaaa aaatcgagtc agagatccat cagaaaatgg aaaaagctgc
    44941 tgaaaacatg gagtttgaaa aagctgcaga ataccgagac cagatccgtg ccattgagac
    45001 aatcatgact cgccaaaaaa tgacaaatac tgatttactg gatcgagatg tatttggtta
    45061 tgcgattgac aaaggatgga tgtgtgtcca agtgtttttc gtaagacaag gaaagctaat
    45121 tgaacgagat gtttcaatgt ttcctttcta taacgaagca gaagaagatt tcttgactta
    45181 cctcggtcag ttttatcagg aaaatgagca tttcattcct aaagaagtct tgattcctga
    45241 tacgatcgac aagcccagtg tagaagcttt gttagctacg aaagtgctgc aaccaaaacg
    45301 aggagaaaag aaaaaattag ttgaattggc gaataagaat gcctcagttg ctttgaatga
    45361 acggtttgat ctgattgcca gaaaacagga acggacgatc ggagcagttg aacgtttagg
    45421 aaacgcgatg aatatcccga ccccaatacg tatcgagtct tttgataact ctaatatcat
    45481 ggggacgaat cctgtggctg cgatggtcgt attcattgat ggaaaaccgg caagaaaaga
    45541 atatcggaaa tataaaataa aaacagtcaa cggaccggat gattatgcat caatgagaga
    45601 agtcatctat cgcagatatt cacgagtgat tcgcgaaggg ttgcctttac ctgatttgat
    45661 cttgatcgat ggaggaaaag gacaagtaga tgtggcaaaa gatgtcttag aaaatcaatt
    45721 aggaatcgat attcctattg ctggcatggc aaaaaacgat aaacataaaa caaatgagtt
    45781 gctattcggt atagatttgg ctgtagtacc gcttgagcga aattcaccag agtttttctt
    45841 actccagcga atccaagatg aagtccatcg attcgcaatc actttccatc ggcagctacg
    45901 cagtaaaaac agttttgctt cccgattaga tgaaattgaa gggttaggac caaaacgaaa
    45961 aaaaatgctg cttaaagagt tcaaatcgtt gaaaaatatc acagcagcca cgacagaaga
    46021 attacaagaa atcggactgc cgaaaaatgt cgcacaaaac gtatttgata aattacatca
    46081 ggaatgagga aagggcactt tacaaagaaa gtaaagtgtc ctatcatttt atgtacaaca
    46141 aaaagagcgt ttacgttttg ttggtaaata ataaatcgct tacgtctggt gtctaaggat
    46201 atatgtgatt tcttgaagaa ggagtgaaga aatgttagaa gtcaaggatc ttgttaaaac
    46261 ttttgggaac tacacagctg tcgatcatgt ctctttccaa atccccgatg gaaaaatcat
    46321 ggggctaatt ggccaaaacg gggctgggaa gacaacgact tttcgtttga tcttggattt
    46381 tttgacacaa gaccaaggag aagtgttatg gaatggccat catcttgggg agaaagatta
    46441 tgatgtcatc ggttatcttc cggaggaacg gggactttat ccgaaagtaa cgattcaaga
    46501 ccaactgctt tattttgcag aacttagagg gaaatcaaga aaagagattg aaccaaaaat
    46561 cgatttttgg atggaaaaat ttcaggtaaa agggaaaaag acggataaag taaaatcttt
    46621 gtctaaagga aatcagcaaa aagtccagct gatcgccacg ttaatccatg aacctaaatt
    46681 gatcattttg gatgagccat tcagcgggtt agatccggta aatgctgaat tgctaaaaga
    46741 tggaatattg gaattgaaaa aacatggttc atgtgtcatt ttttctagcc acaatatgga
    46801 taatgtagaa aaaatctgcg atcatttgat catgttgcga aacggaaaaa tggttttgaa
    46861 tggaaaagta catgagattc gtgaatcatt tggccgtacg aagttattct tggaatctgg
    46921 tttaagccaa caggaagtag aagaaatcga aggcgtgaaa aaagtgatcc ttcatgaaga
    46981 caatacgtta gagattacct tagaagatcc tgaagctggg aaagaaatct ttactcgtgc
    47041 gactcagttc ggctacattc ctatgtttaa ccagcaaccg ccaactttgg aagagatttt
    47101 caaattgaaa gcaggtgaaa tcgatgcgta agttttggat tattaccaaa gatgtctatt
    47161 taaaaaatgt taagtcgatt tctttcttga tcatgatatt agtccctttt atcatgctgg
    47221 gtatcattta tgtagcagga aactttgctc aacaaaatag tgatgtcaat aaaatcggcg
    47281 tattggctga taatgagcaa atcagtcagc aaatgagcca agtcaaaaca gatgattttg
    47341 agttcaaagc agttgattct gaagaaaaag cacaaaaaga gctttcggaa gaaaaaatcg
    47401 atgcgtattt agtagtctca actgagaatg ataagataaa tgggatgctt tatagcgaaa
    47461 attcattagg acaaagtaca caactactga tacaacaaca actgactggc ttgcaatcga
    47521 tgcttcgagc aagtcaatta ggcatttcac cagaagaagt agctagcttg agccaacaag
    47581 caagtttgac tcgacaaaaa gtcaattttg attcaaaagg aaaaatgaca gttggagaag
    47641 ataactcgac agtccaatat gtcgtaagtt atgtagcaac gattgtcttg ttcattatta
    47701 ttttgacgta tgcgcagatc attgcacaag agatcgcttc tgaaaaaggc acgcggatca
    47761 tggaagtgat cctgtccagt acgactgcac aaaagcattt ttacggaaaa ctaacaggtg
    47821 ttttacttgt tgcattaacg caaatggcat tatacggtat tatttttggt ataggataca
    47881 gtcaattcaa agatatggaa atggtcaaaa atatattaga cggtatctca ttggataact
    47941 tgattggacc attcttgtgg tattctcttc tattcatgat ctttggcatt ttgatttttt
    48001 ctgttttagc agctttatgt ggctctttgg tcaacaaagc agaagataca gcaaaagcaa
    48061 ttttgccagt gacttatcta tctctaggcg gatatatgct tggattgata ctaggagctt
    48121 cagatccaaa caatatcgtt attcggatca cttcgtatat tccattctta tcttcatata
    48181 ttatgccggt tcgcttagca aatgagacag tcggtatggg tggagcattg atttccttgt
    48241 tggtacttgt agccgtaaca ttcttattga tgatcttgtc tgcaaacatg tacaaatcga
    48301 atgtactcgt gtatagcgaa ggcggattat ggagttcatt gaaacaatcg atttcaatta
    48361 tgagaaatga acgaaaaaaa gcataaaata tagaaaaatg gctctttgtc aaatgatgtt
    48421 ggtaaagaga aatcttagaa taattggaga tcaagtggat cagttcctct tgatcttttt
    48481 tagttgaaaa tcaatgcgtt gccatgacga atcatgatgc gcaatttgaa attataaaag
    48541 ctacgaaagc catatgcatt tcgttttaac actttgatat ggttgttcag acattcaagt
    48601 gggccatttg aataactttg ttgtaaagca tttttgattt gtggcagaaa tttctggaac
    48661 gttctcaagg tcgtctgata gccttcggga agcatgatat tattggtaag tagttcttca
    48721 aacgatacgt agtctcgttc ctttacagcg taaagaaagt cttgatataa ctgatagcct
    48781 acacgcaaag cagggctccc tttcagtaag cgatccacaa tatcggtctc tgttaaatga
    48841 gctttgaagc caggtcgcca aaggcgtcga gtataatcaa gcttgcgttc atctttttga
    48901 agaagtttcc agtatctttt taattgctta cctaattgat agtgtttttg ttctttgctt
    48961 tttaatagtt ggttcgtttc tttgattcga tgattgcgaa aggtacgacc aatatgttgg
    49021 acgatgtgaa accggtcaat gatcagctgt gcttttggaa acagcttttt aacgagcgat
    49081 acataaggag cgtacatatc aatcacgatc cattcgaccg cttcacgaat ttctcgtgaa
    49141 aaatgactaa aataacgttt taaaaaaggc agttgtcggt tctcgacaat gtccaacaag
    49201 cgctgtgttt gtccatccat catgatgaaa ctcatagcac ctgaaacacc ccgaactgat
    49261 ttgaattcat caaaacaaag taccttaggt aacggtgtcc gaaaaggatt caacggacga
    49321 taaaatcgct tcataatacg gtaaacagaa gagaccgata gatttttctg agcggcgatc
    49381 tctgtcattg aggtattttt tttcagacga gtcacgacag accagcggac tttctcactg
    49441 atgaaacagt gttttttcgc aacagaagta tctgcgacaa aggtccgctg acaagctttg
    49501 catttgaagc gttgcttttt caattcgagg taggtacggc attcagaaac atcgttcatt
    49561 aacaaccgga cggttgttgt accccaacgc acaatatctg aagcaatctg gtgtttacag
    49621 tggatgcatt cttgggctgt ataaatcaag tttccacgat aaatatgaca gatttgccct
    49681 ttgtattttt cttttgtgag acaattttcg ttaaaagtaa ctgataagtc tagaatatct
    49741 aatgtttctt tgataaggtg agtgtaagac atcttgattc ctccttttgg gttggttcgc
    49801 caaattaatt ctaaaggatt tcaaggtgtc ttttctatat gttttggaaa ataaaaaaga
    49861 tgctggtgtc atccaccaac atcaaaaagt atagagctag aaaaatatag aaggaagctg
    49921 gacatttatt gttcccagct tcttttttgt atagacctat ttctattttt ttattatatt
    49981 ggatatatat attcattgaa aatagagcat aacaacttta taatgttgag tataccaatt
    50041 tttggaggcg ttttaatgga ccgctattta gatttacttt cagagaagtt ccctacaacg
    50101 gaagatgtca tcacggaaat catcaatctc gaagcaattt tgcagcttcc aaaaggaaca
    50161 gagttatttt tgagcgatat acatggcgaa tttcctgctt ttgatcatat tctgcgtatc
    50221 ggttcaggaa atcttaaaga aaagatcaaa gaccttttct ctgaacaaat gacggaaacg
    50281 gagatcagcc aattcactat ttttacggct tatccagaat atgtgttgac gactgattgg
    50341 tacaaaaaac aagataaatc ccagctgatc catcgtttga tcgatctttt acggtttacg
    50401 acagtcaaat acactcgatc aaaagttcga aaaggattgc cgaaagaata tagctatatc
    50461 attgaggaac tcttgtatat cgatgatcgt atcaacggga aaaaagacta tgtaaaaaaa
    50521 atcattgaac aacttgtctt gatgaaggaa gaagaaaaat ttttaacaaa acttgcgcag
    50581 acgatccaaa aatctgtcat cgatcatttg catatcgtgg gtgatatttt tgatcgagga
    50641 actcaagcag ccaaagtaat ggatcgaatc atggattttt cctctgtaga tatccagtgg
    50701 gggaatcatg atattttgtg gattggtgcg tattgcggct ctgaggcatg tttattgacg
    50761 cttttacgga ttgccgcacg ctacaactat ttatttgaat tagagaaaga atatggatta
    50821 aatttacgtc cattattttc ttttgcccat caaacctatc agaagaatcc agtatttacc
    50881 cctaaaaaca ggaaagatct atctgaaaga gagcaagaag aattagaaaa gatccatcaa
    50941 gcactttcta tcctccaatt caaatcagaa catcagttgt tgaatcgacg acctgaattt
    51001 aaaatggacg atcgtaaatt gttggaaaaa atcaactatg aggaatcaac gatcgtttta
    51061 gaaggtcagc tctatgagtt gaaagggact tgttttcaaa cgatccagcc agatgatcct
    51121 aaaaaattct tggaagagga acaaaaagtg atcgatagtt tgatgtattc attccagcac
    51181 tcgttaagaa tgcaaaaaca catgacgttt ttgatcgaaa aagggggaat gtatctcacg
    51241 aacaatcagc atgtactgtt ccatggctgt atacctgtag atgaaaaggg gcagctctta
    51301 gcatttgaat tagaccaatc ttatcgcgga aaagaactgc tgggattttt tgaaaaacag
    51361 ataactgaaa gcgcaaaaga tttgactgca aatgaagatt tggcgaccga tttgatttgg
    51421 tatgcgtgga gcgggccatt ttcgccttta ttcggcaaga gtaaaatggc aacttttgag
    51481 cgctattttc tcacagagcc tcatacgcac gtcgaaaaaa gcaatcccta ttatcacttg
    51541 cgagatgaag agtggttcag tgaaaaaatt ttggcagaat tcgatgcaaa agaagaaggt
    51601 tcagcaatca tcaatggaca cacgccagta aaagtaaaaa aaggagagtc accgatcaaa
    51661 gcaaacggaa aagcatttgt tattgacgga ggtctatcca aagcttatca aaaaacaacc
    51721 gggattgctg gctactcatt actatgcaat tcttacggtt tccaaatcgt gacacattat
    51781 ccgttcttgc ctattgaaca acaatttgca aaaaaatctg atcaaacgaa tgtaaaaaaa
    51841 gtgatcgagc agcagctccc acgcaaactt aatcggaata cgacaaaagg aatggaatta
    51901 cagcaacaga ttactcaact ccaaaggctg ttggattatc gaaaggacga ttgagaaaaa
    51961 tgctagccaa cattgctcaa tagactaaaa agcgactgca acaaaaggcg tgtcgcagtc
    52021 tccttcggaa ttagctcaaa aaacggtaaa atattagaag ctatttttct gtttatttct
    52081 ctaatactca ggtcagggcg ctgatttcac gacctcttcc ttaaacggtg ttctcctgcc
    52141 aactcctcgg tcacaagtca caatatccaa caaacatgag aagctgtttt ttgaaattgc
    52201 tccttgtgac tcagagttga acggcaggct cacgacctaa tcagaaaaac gattaaaatt
    52261 cattcacaaa gaaatcgaat aaacgctgtt cagatgaatc tacacgatga gaaagttccg
    52321 gatgccattg gacaccaagg attttgtgca tattatcttt actttggact gcttcaatga
    52381 gtccatcgtt ggaaaaggcg atggctttta acaaaggaga aagatctttg actgcctgat
    52441 gatgatagga attcacaaag tatgaatcag ggagaaggtc acttaataaa ctgtccgaaa
    52501 cgattttgac ttcgtgagtt gcaaactgcg gggcagtggg ctgttgttcg tgttttacgg
    52561 accattttgg atataatgaa agatcttgat aaagtgttcc ctccaacacg acattcaata
    52621 gttgaagtcc tcggcagact gcaaaaatcg gttttctttg tttcaatgct tccaagatca
    52681 atgcctgttc gaattggtct cgttgaatat ttgtttccgt cagttttgga tgagggtctt
    52741 ccatgtaaag ttgcggacta acatcctgac cgcctgcaag aatgagtttg tcgattttct
    52801 caattagttg aggcgctgaa tctggagaca tgactggcag aataagaggt aatccttgag
    52861 catctaaaac tgcatccaca aatccctgcg gtgtatagct tacttgattt ccttggaaag
    52921 tatctgtcgc tcgaatcagt tgattcccgg caatgccgat gattggtttc atttttattc
    52981 cccctaaagt agactaattg taacaaggat ttaaaaaaat ttaaactatg taagacttgc
    53041 ccctatactt atctgttctt gctgtgttac tatctgtaaa gagaattttc gtgtgaaatt
    53101 catgacgata gttgaaaata ttgcttaatt tgttataata aaaagtaagc agaaataaaa
    53161 aggttgggcg taagcttcaa ggatctagtt cttcaagggg tgagaaggac attttattga
    53221 aggggcctgc ctatactaag ttatctttag aggtacatac tttcaatgaa aaaagaaagc
    53281 atgtacctct tttttaaatc gaaaggaagt gaagcaagtg ttagaagctt tggaacaaat
    53341 ccgaaaagca gaagaagaaa atgagaagcg tgctcgaacc ctacggcagc agttgaagac
    53401 ctatgcagaa gaaaaagagc aagaattgga gataatccaa acgaacagtc ggcaacagct
    53461 gaaacagttg gtagaagaaa aagaacaatt cgaaaagcaa gaattagaaa aagaaaaaat
    53521 gaaattgaaa gcagaagcag acaaggtgca agcaactttg aaagaccaat atcaaaagca
    53581 tcagagtcaa gcaatcggtg caatcattga aagggtgaaa gaaacttatg gccgtcacta
    53641 agatggaaaa agtgaccctc atttcagata aaagaaatca ggagaggatt ttacaagcag
    53701 tacaaggaat ccaaaatgtt gaaatccggg atctgtatca aaatagaaca aacaaccagt
    53761 gggtagaaaa atattttcca gataccacga ttattgataa agaagcaaaa ttaagcgctt
    53821 taggcaatcg gctgaaagac atccaagaag ctatccaatt catacaacac cacggcgata
    53881 gccgtcaaaa gaaactccat ttgaaacgtc aagaactttc cttacaagac ttggaagcaa
    53941 attattccga agaaaatttc atgaataaat tagaagaagt ccttgattta aaagaaaagt
    54001 gggaacagct aactgaaaaa cgtgatcgtt tagaagaaga ggaagaatgg cttcttcatt
    54061 ggcaacagct ggatattgct ccaagtatgt atgcaagtaa gacgaccatt tttgagatgg
    54121 ggactgtgag tgcagcaaat tttgaaagtt tcaaggaaga actaagtaag cttgatgacg
    54181 tttatatgga agaaatagat tatacgccaa aacaagttta tctttcgtat gttgctttaa
    54241 aaaaatcagt tgctgctata gaagaaattg ctgggaaata cgggttcaat aaagaaacgt
    54301 atccttatga acaaaatcct aaagaaaaat tgcaagaaac caaacagcaa ttatccattg
    54361 ttcacgagca gcaaaaaaag ataacgacag cgttaggtca gtgcagcggc tatatccaag
    54421 aatttgaatg ggtagaagaa gtcacacttg ccgttgcaga acgggaaaaa gtaaaagaac
    54481 ggtttatcca tgccacttat ctgatcgttt tgcaaggttg ggtagatgca gaagaaaaac
    54541 agaatttgat gcatgtgtta aacgaaactg tatcagaaga agatatatac gttagtttcg
    54601 aaacaccaaa ctcagaagag attcagcagg aagtccctac taaattgaaa aaccatccgc
    54661 ttatcgaacc ttttgaattg ctgactgaaa tgtacagtct gccaaaatat gaagaagtag
    54721 atccaacgcc ttggatgaca ccattttatc ttgtcttctt cgggatgatg gtcgcagatg
    54781 ttggttacgg attgctgatg ctcattggga caatactagc tcaaaaacta tttgttttac
    54841 cccgcgggat gaaacgtttc gtaaaattct ttgagattct ctcggtacca tcgatcatct
    54901 ggggattgat ctacagttca tttttcggac aggcattacc aaaagaacta tttggtatcc
    54961 gcttgccttt cccaatccta tctacgacgg atgacgtcaa tacgattttg attttatccg
    55021 tgattttcgg tctgatacag atcttggttg gattattcgt ggcagcaaag gaaaatatca
    55081 ggaggaaaga ttacttgagt gctgtcagtg atggttttgc ctggcaaggg atcctgattg
    55141 ggatcgttat tgcattgatt ggtgtcatgt tgataaaaaa tacagcattt gtttatcttg
    55201 gcgcggggct atcgatcatt gctgctttat gtatcttaat cgtgccgatt atccaatcgc
    55261 cgtctaaagt caagggtgct gccaaaggag cgtataatct ttacggattg actggttata
    55321 tcggtgattt agtcagttat acacgtttga tggcactagg tatttcaggc ggaagtattg
    55381 gcgcggcatt caatatgcta gttgctttca tgccgccagc cgctcgattc agtgtaggga
    55441 tccttttgat catcgcttta cacgcactga atatgttttt gacactgtta agtgcctatg
    55501 tccatggtgc acgattgcag tatgtcgaat tttttggaaa attttataca ggaggcggac
    55561 gtgcctttga cccgctgaaa acggcggaaa aatacgtcaa catcaatcat aagaaaaaaa
    55621 acaataaata attggaggat ttttatacaa tgatggatta cttaattagt caaaatggtg
    55681 gaatggtatt tgcagtatta gcgatggcaa cagcgacgat tttttcaggg attggttcag
    55741 ctaaaggtgt tggaatgaca ggtgaggcag cagcagcgtt aacaacaagt caacccgaaa
    55801 aattcggaca ggctttgatt ctgcaattgc ttccaggtac gcaagggttg tatggattcg
    55861 ttatcgcctt tttgattttt atcaacttag gaaatgatat gtcagttgta caaggattga
    55921 actttctagg cgcttctctg ccgattgctt ttacaggttt gttttcaggt atcgcccaag
    55981 ggaaagttgc agcagcaggt atccaaattt tagcgaaaaa acctgaacat gctacaaaag
    56041 gaatcatttt tgctgcgatg gttgaaacat atgcgatttt aggtttcgtt atttccttcc
    56101 tattagtatt gaatgcctaa gcataaagga ggaaaagcag atgaacgcca ttgaaaaaat
    56161 catctctcag atgaatgaag cagcagagca agaaagagcg gcgttagagc aagaagagcg
    56221 aatgaagatc gatcaaaact ttgaacaaaa acgtacgcaa atcgaaacag aacatcaaaa
    56281 acaaaaagaa aaacaaatcg aattacttga aaaaaaatac cgtcagctta ggaatcgcca
    56341 acaagtagaa gtacgacaag aaaatttgaa tgcgaagcag gaatttttac gacgattgtt
    56401 tgcagatgca atagctgaaa tggagaattg ggatgaatct gaacaaatcc agtttatcaa
    56461 aaattcattg tattcattac ctttgacagg caaagtaaca ttcattgctg gagaaaaatc
    56521 agcagcttat ctttctcaga cattgctgga tgaatggaac aatgaacttc cctttatgat
    56581 ggttttaagt gatgaaactg ttgctgatca agcgggtttt ctgataaacg atcaaggagt
    56641 tcagtataat tttcttttca gcagccttgt acaagatatc caaggaacga tgagttttga
    56701 gattgccaat caattattcg aataaggagg gatcagtgta tggaatacca cgaactaaat
    56761 cccttgattc gcggaagaga gcttgaactt ttgtccaatg agacatttga acggatgatt
    56821 caaacaaatt ctgtcgaagc acttggtgaa atattgaaat ccacgattta cagtccatat
    56881 atttatgacg gatatgaata tgacttcgaa cagaatcttt taaaggagca gagccgtcta
    56941 tttcgctggt taaaggaatc agcaccggag cctgaaatcg tttggatcta tacgatgcgc
    57001 tatactttcc ataatctgaa ggttttgaca aaagccgaga tgacaaatca aaatctggac
    57061 catttgtata tcgacgatgg attttattca ttagaaacct tgaaggatgc cattcatacg
    57121 caagtttcaa atgaactccc tgaaagcatt atggacagta tacgagaagt acgtgattat
    57181 tttgaagagt ctaccattct tcagggaatt gacgtgattt atgatcgaca gtttttgaca
    57241 gagcagcgac ggcttgccga taagctagga tatcaagaat tgctgacaga agtcattgct
    57301 tttattgact tgaccaatat cacaacgatg gctcgaggaa tattgcagaa aagaacatat
    57361 gggttcatga cgacggtact ttccagctcg ggaagtatcg aaaaagaagt atttttgaac
    57421 tttgtagata aagatatgga agattacacg aattttctat tagagacaga ttatgctgat
    57481 tttctgcgcc ctgtcatccg tgagggaaat cttgatctcg taaagcttga acagttgaaa
    57541 gatgattatc taagttcatt gtatcaagaa gcacaaaccc aggctttcgg accactgcca
    57601 ctactagcct ttttgaacgc aaaagaggta gaaagcaaaa accttcgttt actggttatc
    57661 ggcaaaagaa gccatttcga accagaaaca atcagaaagc gggtgagaca agtctatgac
    57721 gcataagatc ggtgtagttg gcgacaaaga ttctgttttg ccattcaaat tgtttggctt
    57781 tgatgttcgt tatggtacaa ccaagcaaac cgttcgtcag gcaattgaag aaatggcaaa
    57841 gaatgagtat ggcgtgattt atgtcacaga gcaatgtgca gcattgagcc cagaaacgat
    57901 cgaacgttac aaggaacaaa tgatacctgc tatcgtattg attcccaatc atcaaggatc
    57961 attagggata gggctggaag aaattcaaaa aaacgtagaa aaagcagtag gtcaaaatat
    58021 cttatagtat gaaaaggaga tagaaatttt gcaaattgga aaaatcataa aagtctccgg
    58081 acctcttgta atggctgaga acatgtctga tgccagtatc caagacatgt gtctagtggg
    58141 agatctagga gttatcggag aaattatcga gatgcgtggc gatgtggcgt ctattcaagt
    58201 atatgaagag acttctggaa ttggtccagg cgaaccggtt cgctctactg gtgaagcttt
    58261 atctgttgaa ttaggaccag ggatcatttc acaaatgttt gacggaatcc aacggccatt
    58321 agataccttt atggaaatca cacaaagtaa tttcttaggg cgcggagttc aattgcccgc
    58381 attggaccat gagaaaaaat ggtggttcga accaacagta gaagccggag aaacggtgag
    58441 tgctggagat gttatcggga tcgtagaaga aacaaaagtt ataaaacata aaatcatggt
    58501 gccaaatggg ataaaaggaa cgatcaaaac aatcgaaaaa ggttcattca ctattgatga
    58561 aacagtatgt gtcattgaaa ccgaaaatgg tgacaaaaat ttgacgatgc ttcaaaaatg
    58621 gccagtaaga cgtagtcggc caatcaaaga aaaattaaac ccggatgcac ccatgatcac
    58681 tggacagcga gtgattgata cattcttccc agtgacaaaa ggaggagcag cagctgtacc
    58741 tggtcctttt ggtgcaggga aaacagtcgt tcagcatcaa attgcaaaat gggccgatgt
    58801 ggacatggtt gtctatgtgg gatgtggcga gcgtggaaat gagatgacgg atgttttaaa
    58861 tgaattccct gaattgattg accctaatac aggagaatcg ttgatggaac gtacggtatt
    58921 gattgctaat acatcaaaca tgccagtagc agctcgagaa gcttctatct atacgggaat
    58981 cacaattgcg gaatatttcc gtgacatggg ttatgacgtt gctatcatgg cagactccac
    59041 ttcacgatgg gcagaagcac ttcgtgagat gagcggacgt ttggaagaaa tgcctggtga
    59101 tgaaggttat ccagcttatc ttggttcacg gcttgcggaa tactatgaac gatctggaag
    59161 agtcattgca ttaggatcag aaggtcgcga aggaagtata accgcaatca gtgctgtatc
    59221 cccgtctgga ggggatattt cggaaccagt cacacaaaat acattgcggg tcgtaaaagt
    59281 attctggggt cttgattcca gtttagccca aaaaagacat tttccttcga tcgattggat
    59341 acaaagctat tctctttatt caacagaagt agggaagtat atggatcata tccttcaagc
    59401 tgactgggca tccatggtca ccgagggcat gcgtattttg caggaagaac agcagctgaa
    59461 tgaaatcgtg cgtttggtag ggattgattc cctttcagat aatgaccgtc tgacattaga
    59521 agtggcaaaa tccattcgtg aagattattt gcagcaaaat gcttttgatg atgtcgatac
    59581 attcacttca agagagaaac aattcaaaat gttgaagatg atcttgacct ttggtgaaga
    59641 aggacgccgt gcgttgtcgt taggtgctta tttaagtgag atcatggacg gtaccgtatc
    59701 gattcgtgaa aggatcggac gaagcaaata tatcccggaa acagaattag aaaaactaga
    59761 tcaaattatt ggtgaaatca agcaaacgat gcaaacgatc gtttcagaag gaggcatgag
    59821 caatgattaa agaatatcgt acgatcggtg aagtcgtcgg tccattgatg gcggttgaaa
    59881 aagttgctgg tgtcaaatat gaagaattaa tcgaagtccg tatgcaaaat ggcgagattc
    59941 gtcgtggaca agtattggaa gtccaagaag ataaagcaat ggtccaaata ttcgaaggaa
    60001 caagtggtat caatttacgt gactcttctg tacgattttt aggccatcct ttagaactag
    60061 gtgtatcgga agacatgatc ggtcgagtat tcgatggttt gggacgaccg aaagataacg
    60121 gaccagagat cctgcctgaa aagcatttgg atattaacgg agaagtaatc aatccagtag
    60181 ctcgggatta tccagatgag tttatccaaa caggtatctc tgcaatcgat catttgaata
    60241 cattagttcg tgggcaaaaa ttaccagtat tttctggctc tggtcttcct cataaagaat
    60301 tagctgctca gatcgcgcga caagcaacgg tactcgattc atcagatgat ttcgccgtag
    60361 tctttgctgc tattggaatc acttttgaag aagctgaatt tttcatggaa gattttcgtc
    60421 aaacgggcgc aatcgaccgt tctgtcatgt ttatgaattt agcaaacgac cctgcaatcg
    60481 aacgtatcgc tactcctcgt atggctttga ctgctgcaga atatcttgct tatgaaaagg
    60541 gaatgcatgt tttggttatc atgacagaca tgaccaacta tgcagaggca ttgcgagaga
    60601 tttctgcagc acggcgagaa gttccaggaa gaagaggata tcctgggtat ctttacacga
    60661 acttagctac tttattcgaa cgagcaggaa gaatccgcgg actaaaagga tcggttactc
    60721 aaattccgat tctaacaatg ccagaagacg ataaaactca tccaatccct gacttgactg
    60781 gttatattac agaaggacag atcatcttga ctagagagct ttacaagagt gggattcagc
    60841 caccaattga tgtactcccg tctctttcgc ggttaaaaga taagggaact ggacccggaa
    60901 agacaagaga agaccatgca gctacgatga atcagctttt tgcagcctat gcacaaggaa
    60961 aacaggcaaa agaattagcc gtagttttag gtgaatctgc tttatctgat gtagacaaga
    61021 tctatgcgaa gtttgctgag cggtttgaaa aagaatatgt caatcaagga ttctacacga
    61081 accgttcgat tactgaaaca cttgatctag ggtgggaact gctatcgatg ttgccaagaa
    61141 ccgaattaaa acgaatcaaa gacgacatgc tggacaaata tctgccagaa gggaagtgag
    61201 ttctgatggc acgattgaat gtgaatccga cccgcatgga attgactcga ttgaaaaaac
    61261 agttgacaac tgccacaaga gggcataaat tattaaaaga taagcaagat gaactgatgc
    61321 gtcaattcat cctgttgatt cgaaagaaca accagctgcg tcaagaaatg gaagagtcta
    61381 tgacagaagc aatgtctgat tttgtattgg caaatgcttc gatcacggaa cctttcatcg
    61441 aagaattatt tgttttgccg gcggaaaacg ttgatttgtc tatcgtagac aaaaatatca
    61501 tgagtgtaaa agtacctgtg atgaattttg aatatgatga acagctgaca gacacacctt
    61561 tggaatacgg gtatttgaat tccagtgccg aactggatcg gtcaatcgat cggtttacta
    61621 ccctgcttcc aaaacttttg gaactgacag aaatcgaaaa aacttgtcaa ctgatggcga
    61681 gtgaaatcga aaagacacgt cggcgagtca atgcattaga atatatgacg atccctcaat
    61741 tagaagaaac gatctattat attcgtatga agctggaaga aaacgagcgc gcagaagtaa
    61801 caaggttgat caaagtaaaa aatatgggta ccactgacta agtggtatct ttttttaaaa
    61861 gaggaaaacg atgattaaac aaagcaaaca aataaagaaa cgtttgccgg ctgttcagct
    61921 tcttgcatta ggattttttc tcctgatttt agttggcggc ggcctactta ccctaccatt
    61981 ttttagtaat agtgggcatg ggacaaattt tatcgatgcg cttttcactg caacttctgc
    62041 tgtctgtgta acgggattga caacattgaa tacagcagag cattggaaca gtgctggtca
    62101 atttttgatc atgcttttga ttgagatcgg cggtcttggt tttatgatgg ttccgattct
    62161 atgctttgca ttgataaaga agaaagtcag tctcagcaca cgtattatat taaaagaagc
    62221 gctgaatcta gaagaagtat caggtgtgat gaagctcatg ctttacatcc taaaattggc
    62281 ctttgttatc caattgattg gtacggttgc tttatctttt gtatttgtgc ctgaatttgg
    62341 ctggttgaaa ggtatctggt acagtttgtt ccatgcaatc tctagttttt gtaatgcagg
    62401 gtttgatttg ttaggagaca gtttagccaa tcaccagcaa aatgtttatt tgatcatggt
    62461 ggtatctgct ttgatcattt ctggtgggtt aggcttcatc gtatggcgtg atttactgga
    62521 atatcatcag aaaaagaaga tgacgattca ttcaaaaatc gcattaaccg ttacaggtac
    62581 ccttttatta ggcggattcg ttgtgttctt tttcacagag cgcaatgggg caacgctagt
    62641 ggaagggaat atgtttcaac gattggcaaa cacctttttt atgagtgtga cacctagaac
    62701 ggctggatat tattcagttg attacctcca tatgagccat gcaggtctga ttttaacgat
    62761 gtttttgatg tacatcggcg gaacatctgg gtcgacggcc ggcggattga aaacaactac
    62821 gttaggtgtg ttgctgatcc agatgcgttc gatgttgaaa ggacgtacga gagcggaagc
    62881 atttggccgt accatccgac aaggcgcagt gttgcgggca cttactttat tttttgttac
    62941 gttgacgttg tgtgtagtcg ccatcatgat tttatcggtg actgaaacga tacctaaaac
    63001 ttctggcatc gaatatattg cttttgaggt cttctctgcg tttggtacag taggtcttac
    63061 gatgggattg acgccagact tgactgcaat agggaaattg atcattatag cgcttatgta
    63121 cattggacga gttggtgtat tgactgtggt cttctctctg atgacaaaag cacaaagaac
    63181 acaatcaaaa tacaaatatc cagaagaaag tgtcatgatt ggataatttc atcttctgac
    63241 agaaacctag tgatttagta aaataagaaa ataaaataat ttttcttgct tcttggatac
    63301 tttaagtgca aaatgttcgt ttattttttg aggcactacc cgttgttgaa cctcgggtag
    63361 tgcctctttt ttattgaaag gaatcaataa gatttgattc ctttatttat caataggtta
    63421 taattcatat ttttttattt tttcttttac gatacttagt ccagaagcta aaatttcaag
    63481 gttattagag gatagggaaa ttcgaacgaa tgcatctggt tgcgcacgtg tagtaaagcg
    63541 tctggaatga taaagtcgga taccgttagc aagaaagtca ttctcaatta tcttagggtc
    63601 aatctcagga tcaactggaa gaattcgata gtaagggaca cgattcgttg gtttttctac
    63661 tttgaaaaga gaatcaaaaa gctgattggc tctttttgta agacttaatt tagtttctaa
    63721 gatcctattt gcttcatttg aatggaggat ttgagtgatg acttccacat ctaatccaga
    63781 agttttcaca tttatattaa aaattgcttg ttctatcttg ctttggacat gtactggaac
    63841 tacaagataa gcaactcgca atccagaaca aataaatttt gtcattccag ctaagtagat
    63901 tgtttggtta ggtaataaat tttggaaagg aggaatgatc gtatgttgat agtaagttgt
    63961 taaaaatgaa tggatatcat cttcaataac ccatagacct tctttttcaa tcacttcggc
    64021 taattgctct cgtcttttgt gagagatttg aaaccctata ggattattac aagaaggcat
    64081 aagaaagaca ccatgaatct tcttttttct acattcctga atcaatatat caggtcgcat
    64141 tccttgctcg tcaaaatcaa ttggaacgat ctctaaatga tataactgag ccaattcaat
    64201 gaaattagcg tatgtatatc ggtctgttgc tattctatca cctggagaga aaagtgcaga
    64261 aagtgtgata gccaatccat tttgaacacc ggaaacaata gatagagatt ctaaggacgg
    64321 aatgactcct tgagttttta accaatttgc tgcagtagtc aattgaaaat ttgtgccttt
    64381 gggatcttgg taattaagca aaccaacaag atttgggtta ttactagttg attgaataaa
    64441 cgggacaacg aatttattac attcttcaaa agaactaacc agaccaaaat caatgatatg
    64501 ttcggttact tcattggtag agatggtgat ggactcaaag acattgggag aaataaatgt
    64561 gccacttcca atattcgtat acagcaaacc tttctcaatt ccatatttat aagccttgcc
    64621 aacggtagta aaatttaaat ctaaataatc agctagctct ctttgggagg gtaactgagt
    64681 gtttttctgt aatttattct ttaaaatatc ttgttctaat tgttgaatca acgatcgata
    64741 ataaggacgc ttcaattttt gtttgtctgg tcgccaagtt aacgggtaat tgtcataaga
    64801 attaataggc attttctcca ctccttaaaa ttgtatacca tacaatttta ccattgattg
    64861 tattgatttt agaagttaat cttttgtgag gagggaattg tctatgaaaa ttattaattt
    64921 tgaggaagta gtagcttctt ttagttttga agaagcgatt caagtaatga aaaaatgttt
    64981 ttttgattat gaaagtggta aaatcagcca aaatcctcga ttggtggaaa ttttacctga
    65041 cggaaaaggc aaaaatatgt ttgcgatgat gcctgcttat ttgggggaga acagatattt
    65101 tggcacaaaa gtcattaccg cttttccgga taatcatcag tatcatttac cttctcattt
    65161 aggagagatt ttcttgtttg atgctcaaaa cggactaccc aaagcattga taaacgcaaa
    65221 tgcagtcacc tggattcgaa cagctgctgt atctgcgctg gcaacagatt acttagcaaa
    65281 tccgcatgca gaaacacttg ctttaattgg agctggtcaa caagcattgt cgcatttgac
    65341 tgcgatttct accattcgtc ccatcactac agtgtttgtt tacgatattt tagaagaaag
    65401 acgaaatact tttatcgcta aagctaaaaa acagtatcct aaaataacgt ttataaatgc
    65461 aatatcagta gaagatgcag tacgtccagc ggaaatcatt tgtacgttga cctctagtaa
    65521 agaggcattt cttcaaaaag agtgggtaag ggaagacgca catatcaatg ctgtgggcac
    65581 atttactcct gatacaagag agataagtac atcgttgatg gaaacttctc aaatctatgt
    65641 agatgattac tcagctgcct taacagaaag cggggacctg cttatagcca tggcagaagg
    65701 agatttagag gaatcttgta ttgttggtac attaggcgaa ttagtttctg agaaaaaaac
    65761 attttataaa ggagaatcga ggccgacgat tttcgacgca gttggtctag ctattgaaga
    65821 tctttgttgt gcagaatata tttataacaa attagagaaa ggggctttaa aatgaactta
    65881 gattattacg tagttgatgc atttgcagat gaggtgttca aaggaaatcc agcagcggtt
    65941 tatgtgctag aagaatggct gccagaaggt acgatgcaaa aaattgccat tgaaaacaat
    66001 ttatctgaaa cagcatttac agtgaagaaa aaccaagaat ttgagcttag atggtttacg
    66061 ccagatcgag aaatcgatct ttgtggtcac gcgacattag caacagcatt tgttttattt
    66121 aactattaca aaatacctga tgaaacgatt aaattttcta ctcaaagcgg taatctattt
    66181 gtgacaagaa ttaaagatta ttattacatg gattttccta gtattatgcc gaaaaaagtg
    66241 ccgatattgt ctgaatatga agaagcgatt ggggctaaga ttaaagaagc ctacttagca
    66301 cgtgatttat ttttcgtatt agaagatgaa aaaacggtgg ctaaattgca gccagatttt
    66361 acagctatca aaaattttga attaggaata ggagtcatcg tgacagcaga aagtgtgcaa
    66421 aaagactttg tttctagaac cttctttcca aaattaacaa tcaatgaaga tccagtatgt
    66481 ggatcagcac attctaatct tattccttat tgggcagaaa gaatgaataa aacaaaattg
    66541 tcagcttatc aaatgtcatc aaggggcggg gatctagaat gtgaattaaa agaagatcgt
    66601 gtgataatag gaggaaaagc agttttgttt tctaaaggta cctcgtttat ttgatttctt
    66661 tcaaatgaat taaaaataaa ttggtggaga gtggcaacct tatagctaca atggttgtta
    66721 aaaaaagacg caaacttttt caatttaatg aaaagtttgc gtctcatttt aattattggt
    66781 gtttgttttt tattcaatca agagtaaaat gccccatact aactatcctc ggatgacttc
    66841 gattttataa ccatcagggt caatgacaaa gtagtaagaa ggcgcagtgc caggtaatcc
    66901 ttttaagtca gtaatctcaa gaccggcagc tttatgttgc tcgtgtaatt tttctagatc
    66961 atcagctgct atagcgatat gaccatagcc gtctcctaga tcatacgcac catgatcata
    67021 gttgtaagtc aactctaatt catagtcatc cccaggaagt gtcaaataaa caagtgtaaa
    67081 tttgttttct ggaaaatcac ggcggcggct ttcttcaaaa ccaaatgcct tttgataaaa
    67141 ttcgattgat gcttcaagat ctttcactcg aacacatgtg tgagccattt tcatagattc
    67201 atctctcctt ttccttttac tcaatcataa caaaaagaag taaggaaata gttgatttgt
    67261 gcttgttcat gagaaatttc tcatgtaaaa tggatagaaa ataaaactgt taaggtggaa
    67321 actattcatg gataaaccaa tttttggtga aaaaaagcaa tttgctgatt atcaaacccg
    67381 ttatgcagca tatattgtca tagaaagaga tcagcagatt gcagtaatcg aggctccaaa
    67441 tggtgctttt tttcttcctg gcggggaaat tgaaggagaa gagacgaaag aagaagcgat
    67501 tgtccgtgag ctgatagaag aaatgggaat tgtggcagaa atttcttctt atctgggaga
    67561 agctgatgag tatttttact cgaattatcg tgcaacttat tattataatc caggatattt
    67621 ctttgttgct gattcttgga agcgtatagg agaaccaact gaaaagacca ataaaatttg
    67681 gtgggtgagc cctcaagaag cgcttgtgaa attgaaacgt ggtagccacc gatgggcagt
    67741 cgagagatgg atcgaaaaaa ataaaaactg aaagaaagcg agtagatcag ctttctctca
    67801 gtttttttat ttattacagt acatattttt tgattgcttc agctacaccg tgctcgtcgt
    67861 ttgatgaagt gatgacattt gctgcttctt tgacaagaga aacggcattt cccattgcta
    67921 ctcctagacc agcatattca atcatggata agtcgttctc gttatctccg atagccatga
    67981 tttcatcttg atcaatacca aggtgctgtg cgagattcgc aactgccgca cctttacttg
    68041 cttctttatt tagtacttcg aagtaatagg gcgcactttt gaccgttgtg tatttatcac
    68101 ggaaagtttg cggtaaacgc gcaattgctg catctaaaat ttctggttcg tcgatcatca
    68161 tcattttgac gatgttcatg tctggtgtca tttcttcagg tgttcgatat tttagcggca
    68221 tcttgactaa acttgcttcg tggatcgtat aagcgctgat atctcgatta ggcgtgtaga
    68281 tcgctttgtc atcgatcgaa tggagatgac tgccgacacg gcgtgccatc acttcgatct
    68341 ctaggaaatc ttcatgtgtc agtccgtgac gggcgatgat tttacctgat ttcgtttgtt
    68401 gtacgagtgc cccgttataa gtaataacgt aatcattatc ttgaaaaagg ttcaactcgt
    68461 ttaactgttc ctggacacct ggtaagggac ggccagtgca taaaacgatc gaaacacctt
    68521 ttgcaacagc agcggcaatc gcttctttta cttcttttgt tacttctctt ttctcattta
    68581 ataaagtacc atcgatgtcg atagcgacta gtttgataga cataatttcc tccaatatat
    68641 tttaatttat ttcaatcaat gcgccattac ggatatggct ggcaaattct tgataagttt
    68701 cgtcaaataa atcataatga tcacgcaagg acggatcaac catttctttt ggaaagaaaa
    68761 atcgctcatc tccttgttct tgtcccgcta atgcagcaac aagctgacta acctgtgata
    68821 attctatcaa agttccgtca tttcgcaaaa tctcgatttg tgtgcgatgt ctgccttgtt
    68881 ctgggcgata aaaatcataa ggtagatcgt agctagaatt cacagcagtg taataaacag
    68941 gattatatcc gaccttttct actaacaaag tgagttcttg gactaatttt gaatcccggt
    69001 tgccagaaaa agtagcagat ttcagtggtt tacgattcaa aaaacgttta gctaaatcat
    69061 ttaaaatagg atcagcagat tcagaccatt gagtaaagta agtgcccaag accccatcat
    69121 caagtttgag gtattcttct aaagtaaagc ttccgtcaag aaatggcaga agtaattgag
    69181 aatggagttc aaaactgctg gcatcttctt gatacaactc gtgtgcgcga tgaagcagat
    69241 gctccaaaat tacttccata ccacgggaaa caggatggaa gtacacttgc acatacattt
    69301 gatatcggct aacgatataa tcttccactg catgcatgcc actcatggaa aaagcgatcc
    69361 cgccttcata aggacgaatc acacgtaata ttcgggtaag atcaaatgtt ccatattctg
    69421 ttccagtgaa ataagcatcc cgaagcaaat agtccattcg atctgcatcg atctgactag
    69481 aaatcatttg gacaacttgt gggttggggt aagttttttg gatcacacta gctacctttt
    69541 caggaaaacc ttcttctact cggttaagaa tctgatacac ttctgtttct ggagaagtga
    69601 tgatctctac agtgatggct tcatgattcg tatggaagat atgttcaaat gtatgagagt
    69661 aaggaccatg accgacatca tgcaacagtg ccgcacataa agtcaccagc cgttcctgat
    69721 catcccagcc tccgttgcct attttttctt ttgaaaaatt tcgagaaaag atatcgcaga
    69781 ttcgtcttga aatctcataa acgcctaatg aatgagtaaa acggctatgt tctgctccgt
    69841 gaaaagtgaa agaagaagtg cctaattgtt taatgcgtcg tagacgttgg acttctttcg
    69901 aattgatcaa atctaagatt acttgatgct ggacatggat atagttatgg actggatcac
    69961 gaaaaacttt ttccataggc agcatttgat atttataagg ggttgtcata atgtagctcc
    70021 tttatgttat tacgttgttc cattctctgg atttggttgt tccattgctc cagctggatt
    70081 tcttttttta gccagtcggt agaatcctgt aaatcacttg cagaatacag cttttcaaaa
    70141 gcttttgcaa atgcttcttt gacttctttt acaaaaaggg gttggtcaag cagttcttca
    70201 agtgttgcca ttgtagcagg atccactgca ggatagccat ttgtaccaaa gtcttctttt
    70261 aaagcagatt gataaaatcg cttcatgact tgcccgcgtt tttcctgatt accgttgaca
    70321 cttaagtaca tcataacaga aatcccattt ttgatccgac gctgagcgat accggcaaat
    70381 tttttgccat ggatgcttaa atcataagtt ccaggacaat aagaatgggt gatttcgaat
    70441 gcttgtatcg gtgcctttgg aaaagcgtat ttagtcaata ggagcatttg ctcgtaagcg
    70501 tcatctatgg ttattttttt tgtgtcactt tgggggaaaa tcaaagaaat attcaaaatt
    70561 ccttcatctg atacgatccc taatccacct gaatttctga tcactggagc gtaacctgca
    70621 tctttcagtg tttggatccc gtcacttaga aaaggagttc gaacatcctt catacctaag
    70681 atgactgtgc agtcatattg ccagaaatgt aaaaagattt gctggtgttc tttagaatat
    70741 tccgttaata tatctgttaa tgcaaaaggg gaaaagtcgt ttttttgata aatgtgctga
    70801 tctagtcgaa tcgcagggtt cattcaaccg gctcctttgt ataaattcat attttctaca
    70861 atattatact ctaaaatcaa agagttgttt tggaaaaaag gttttctgta aaaatggaca
    70921 agttggttga caaaacaaaa gaaactagga acaatgtagc tatgagaagt aaaggagaat
    70981 gaataatgga attatcacaa ggaacaccga tttcaatcaa attgcgtaca aaagtaaaac
    71041 agcaagggga agtgcaagat ttttattttg atttgaaagg gcaaatggtg acaattggcg
    71101 atacgctgta catacgttat aaagagattc aggaggagac gggcgatgag attcctgtaa
    71161 cgatcaaatt agttccagat ggtcatgtac agctgatccg tgcaggagaa atgcggatgc
    71221 gtttgaaatt tggctataaa gaacggttag aaacatccta tcgaacacca tacggtatga
    71281 tccagattgc tacttttacg aaagaactgc atgttagttt gaaagaccgt cccacaggag
    71341 ggaaggttcg aatcgattat gatctgttca tgggaccgga aaaaatcggc gaatattatt
    71401 tgaccttgga ttttacagcg taaatataaa agaaaagttt gattttttgt gtctgatttt
    71461 gtatgataag gagtagactg tgaaaggacg tgtcctgatt ggaaattagt gtatttgaag
    71521 gtgcaaacaa aagcgaatta tcaatgatcg aagtagcaca cgcgatctta gaacaacgtg
    71581 gcgatgtcat ggatttttct gatttagcta accagatcca aaactatctt gggaaatcag
    71641 acagtgaaat tcgtgattca ctcgcacaat tttatactga cttgaatatt gacggcagct
    71701 ttatctcatt aggggataat cgttggggct tgcgttcatg gtatgctatc gattcgatcg
    71761 atgaagaagt aaaccatgga atggacgaag aggatgaaga tactccacgt cgccgtaaac
    71821 gcaagaaagt caacgccttt atcaatgatg atgaagacgc gatcgattac aatgacgatg
    71881 acccagaaga tacagatctg acagaagaag atgacgatga tctgtttgat gacgatgatg
    71941 atgaagatga agaaatcgct gcttataatt ctgacttgca agaaatcgga gcagatgacc
    72001 cgacagatga tgaagaagac ttgccaggaa atatcgaaga agatttaagt atcatagacg
    72061 aagacgatga tgatgaagat tatgaagagg aagaattttc tgactctgaa aaagaataaa
    72121 cattattttc ttacgagagg ttgtgacaga gacgatcagc ctatcagaat aaggaggtgt
    72181 gacacgattt ttgtcacacc ttcttttttg tatataaaaa tcccaagtaa atacataaaa
    72241 aataaaaaaa ttgaaacttt tagcgcacct tgtacgtcat attaagtgag gcagaaagga
    72301 gtggagaatg atttttactg gatataagaa aaaacggcag atcgaaaaat accgtcacct
    72361 gctgaatgga ctcatcgaaa ctgattatca aaaaatgttc cgtatcacga tgaattacgt
    72421 acatgataaa gaagaggcct tagatgtgat gcaagatagt tttcataaag ccctgaacta
    72481 ttttgaaaaa gaaaaagaga tcgagcattt tagtgcatgg ttttatcgga tattgatccg
    72541 cacggcatta gatagttggc gcagacaaaa aaggacgcct gtggacttat ttgaaattca
    72601 agatatcccc caacagttac ctttagaaac ttccgttgca gagctccata tgattttaga
    72661 taaaatagac agtccggaaa aagagattct gatcctctac ttttttgaag gatttcgttt
    72721 gaaagaaatt gcgactatct tggatatgaa tgaaaacaca gttaaaacga aaatgtaccg
    72781 ctcattgaat gctttacgtc aaatcctaga atgaaggaga gaagagtgcc atgtattccc
    72841 aaaaagaaaa tttaaaaaaa ctaaagaaaa cttataaaga acaagcaatt cccaaagggc
    72901 ttaaagagga gatccgccag cgttttatta tcgaagagca atcatttata aaagcaaagc
    72961 ggagaaagag acgtctccaa gggttcggag tatctttggc tatcgtaatg attacaacaa
    73021 gtagccttct ttttaatagt caagttcgaa gctttgcaga agatttaccc atcttaggat
    73081 cagtcattga attgatctta ggcgaacgct ttactgatcg atctgaaaaa atcgatattc
    73141 aggtaccgaa gatcaataca caaaatgaga aagaaaataa aacaattcat ggattaaatc
    73201 aaaaatactt tcgcgaagga caagcagatt ttgaaaaagc tgaaaaagaa tatggaaatt
    73261 ttgaaacgga tcattaccaa gttttgggag attatcagaa aatcgtagac gataaccggt
    73321 ttctcgtgat tgaaaggcag atcacccaaa cagcagcaga tagccatgtt gaaaaaagat
    73381 acgacacaat cgacaagaaa aacagtgtcc agctctcact tccactttta ttcaaagatg
    73441 acacctatct atctgttttg acaaaagaag tcaaacggca gatggccgaa caagtcaagg
    73501 aagatccatc taagtactat tggactgagc aagatattca agaagggacg atagaaaaac
    73561 caacacttgt tacgcctaca cgaagttttt atttgaacaa agagcatcaa ttagttttga
    73621 ctttttctca atacgaaatt gctcctggtt atatgggtac accagaattt gtcattccta
    73681 agtccgtgac aaaaacgatt ttggcatcgg aagattattt ggatcattag acgagaagta
    73741 gttgcgacta gcagtttcaa ttttcaagta agtacaagta aataataaga agagaaaaag
    73801 agaaagaaga gatatagtga aaagaaatta tttagttatc agtattattg ctttatccgt
    73861 gcttttgttt ttcgaaatta cttcggtggc ctccttgatc accgaagtaa aaggacaaac
    73921 acactcttcg gagcattcgt cacaatcttt caaacaatca gaacaatcaa ccattaaaag
    73981 ccaatcaact gaaacagcta acgtcaaaga agccattcaa gaatcagcgg aaaaggtaca
    74041 aagtcagtca tcacaatcaa cacaagacag tacaaaaacg agccgagatc cggctgtcaa
    74101 aagcgtcgca atcagctttg atgatggacc aggagcgacc acaacaccgc agcttctgcg
    74161 aatcttaaaa gaaaaaaacg tgcatgccac ttttttcgtc ttaggagaaa atacggcgca
    74221 gcatcctgaa atcgtgaagc agacagctga agcagggcac gagattggca attacacata
    74281 cgatcatcag aatctggcca ctctttctgc ccagtcgatg acggaggaag tgacgaaagc
    74341 agacactgag atcaaaaaag tcactggcaa aacccccact tttgttcgtc cgccctatgg
    74401 ttctgtcacg aatgtaggag caacgatcat ccagcgaccg atcatcgaat ggtctgttga
    74461 ttcagaagat tggaagacaa gaaatcctga tttgattttg cagaagatcc aagcaacagt
    74521 atacgatggg gcaattattt tattccatga tatctatcct gaaacgattc gtgccgttcc
    74581 tcaagtgatc gattatctga aagagcaagg gtatcgcatc acgacagttg gggatttatt
    74641 agggcatcca acggctgtcg agaactatta tggcagaaac gatcatcggc cagttcagta
    74701 agtgagacaa gtatctttaa taaataacac attttaataa gtagttgaac acataactac
    74761 cttacttgca aaggcttaac aatatctata caggtacaac aaaaaactgt ccaccaattt
    74821 tctttggcgg acagttttca cttaaaaata aagaagcaac tattcgtaaa ttatgctaaa
    74881 atagcagtag aacgcgtcct gagggaatcg aacccccgtc tcaagaaccg gaatcttacg
    74941 tgatatccac tacactaagg acgcaagcac tgggataatt gtaactaaac agataaaaaa
    75001 ttacaagggg attggacaaa aaaatgaaat ttgagcaaaa tttttcacaa aaacagcagc
    75061 agacacagaa actagccatg acgcaacagt tgcaacagtc catccaagtt ttacaatata
    75121 acagtgagga gctgttggca ttcgttgaga atcaagcaat ggaaaatcca ttggtggaag
    75181 ttgttgagcc ggaatggcag ccagattaca taaaagcttc ttcatcttct tatgaaggag
    75241 aagagacaaa ttacctaaat cagattcctg atacaaaagg gtctttattt gattcattga
    75301 tcgaacaagt ccatttgaat taccgagata cttttttgag gaaaatcgtt ctttatcttg
    75361 tagaatacat cgatttgaac ggatttttga cgattagttt agaagaagcc ggaaaagaga
    75421 ttggagctac gcctatccaa atgctcgatg cgttgactct gattcagcaa ttagaaccag
    75481 ctggagtagg tgcacgtagt ttgcaagaat gtctcatgct tcaaacagaa cgagatgatt
    75541 atgcgccgga attagcttat atcgtgttgg aagaatgttt tgaggaactg gtggagcgaa
    75601 aatggaaaga aatcgcacaa cgtttttctg ttgatctaca tgctgttcag cagatattcg
    75661 actatttaca aacgttgagt ccaagccctg gccggatttt cgaccgtagc agcgaattgt
    75721 acattattcc tgatgtccgg gtattagtgg acgacgataa aaatgtacaa gttatctcaa
    75781 accgaaaaaa tcagccaaat atacgctttc aagagagtta cttcaaacaa atgtcacaac
    75841 aagcagataa agaaactgaa aattatttaa aagaacggaa acaggaattc gaatggttga
    75901 agaaaacgat cctacaacgt ggggatacaa ttttgcgggt tgctcaagtc attgtttccc
    75961 ggcaaaaagc tttctttatc gacaaggaac gtccaatcaa gcctcttacg ttaaaggaag
    76021 ttgcaactga gatagatgtg catgaatcca cggtcagtcg tgcagtcaac gggaaatatt
    76081 tggaaacaga tttcggtgta tttgaattaa aaaaattttt cactacacga attcctacga
    76141 atagtacaga acagacagaa gacctttcag cagatacagc gaagaaaaag ctgcaggaat
    76201 tagtcgatca agaagacaaa aacaagccgt tgtcggacca gaaattggtt gaattgctga
    76261 aaaaagatga gatagcgatc tcaagacgaa cagtagcaaa atatcgtgat ttattaggaa
    76321 tcccgagttc atcaaaaaga aaacgttatg ataactaatc agtcaaaaga ctagaaaaag
    76381 tatttcactt tttctagtct ttttagttga aaaacgagag cgaaactgtt agacttacag
    76441 tcgtgaggtt gagatttccc tttattgatg tgaaattcga atagttaatt tcttttttta
    76501 tcgtatatgg gtcgttttaa gtctacattg gacgtaaagt gtccaactaa ggagatcgct
    76561 atgctggatg aaataaaaat gattgaatct gttgcaccag atattatcga agtgttgcaa
    76621 gaacgctata aaattttacg aaatatctat tggatgcagc cgattgggcg tcgaagttta
    76681 tcggaaagta tggggatcac agaacgagtc ttacgaacag aaacagacct tttgaaaaat
    76741 ctgaatttga tcgacacctc aaaaagcggt atgacgctga caactaaggg cgaagaagtt
    76801 tatcaaagcc ttgaaaactt catggatcag cttttaggta cgcatcaaac cgaacaacag
    76861 ttggcagaat attttggtaa ccaacgctgt atcgttgttt caggaaacag cgaagagcag
    76921 accaaagtgg ctgatgcatt cggcgaagcg ctgagcgaag ccttagaccg actacttcca
    76981 gaaggcgaga atatcatcgc tgtgatggga ggaactacta tggctgtggt agccgaacaa
    77041 ttgtctaatc tggaaaataa gaaacggcat aacctgtttg tccctgcaag aggcgggatt
    77101 ggtgaagcga taactgtaca ggcaaattct gtcagtgcaa gaatggctgc taaagcaaac
    77161 ggtaaccacc gcgcacttta tgttccggaa caattaagtc tggcaactta caattcttta
    77221 ctcaatgagc catctatcca agaagtctta aacttgatta gtgaagcgaa ttgtgttatt
    77281 catagtattg ggcgtgcatt acacatggca gcacgtcgta agatgactga aaaagaatta
    77341 gtcatgctga aacaagcaaa tgctgttgcg gaatcttttg gctacttttt caatgaaaaa
    77401 ggtgaagtcg tttataaggt ccctagaatc ggcatagaat tgcaagattt ggaaaaagtc
    77461 ccgatcatca tggcaatcgc gggcggaaaa tcaaaagcta aagcaattcg agcttatatg
    77521 aaaaatgcac caaaacaaac gtggctcatc actgatgaag ctgctgcaaa tgagatttta
    77581 aaaggggtaa ccctttaaaa taaatatttt tttgattttc ataaggagga aatcttaaat
    77641 gacagttaaa gtaggtatta atggttttgg acgtattgga cgtctagcat tccgtcgtat
    77701 ccaagatgta gatggaatcg aagtagtagc aatcaacgac ttgacagatg ctaaaatgtt
    77761 ggcacacttg ttaaaatacg acacaactca aggacgtttc aacggaacag ttgaagttca
    77821 tgaaggttca ttcaacgtaa acggaaaaga agttaaagta ttagctaacc gcaacccaga
    77881 agaattacca tggggcgaac taggcgtaga tatcgttcta gaatgtactg gtttcttcac
    77941 ttctaaatca gcagctgaaa aacatttaac agctggtgct aaacgcgttg ttatctctgc
    78001 tcctggcgga aacgatgttc caacaatcgt ttataacaca aaccacgaaa cattaactgg
    78061 taaagaaaca gttatctcag gtgcttcatg tactactaac tgtttagctc ctatggctaa
    78121 aacattgaac gacaaatttg gtgttgttga aggattaatg acaactatcc acgcttacac
    78181 aggtgaccaa atgactctag acggacctca tcctaaaggt gacttccgcc gtgcacgcgc
    78241 tgctgctgca aacatcgttc ctaactcaac aggtgctgct aaagctatcg gtttagtaat
    78301 tcccgaattg aacggtaaat tagacggagc tgctcaacgt gttcctgtac caacaggttc
    78361 attaacagaa ttagtaacag ttcttgaaaa agaagtaact gttgacgaaa tcaatgcagc
    78421 aatgaaagaa gcttcaaacg aatcttacgg atacaacaca gacgaaatcg tttcttcaga
    78481 tatcgttggt atgacttacg gttcattatt tgatgctaca caaactaaag taatgacagt
    78541 tggcgacaaa caattagtta aaactgttgc ttggtacgac aacgaaatgt catacactgc
    78601 acaattagta cgtactttag aatacttcgc taacttataa gatagacaaa cgtacaagtg
    78661 taaattatag acatgtacat ttaaaagcgg ggaagcaatc gcgcttcttc cgcttttttt
    78721 gataataagt ttattcagga ggaaataaaa tggctaagaa aacagtgaaa gatatcgatt
    78781 taaaagacaa aaaagttctt gtccgtgttg acttcaacgt tcctttgaaa gacggcgtga
    78841 tcactgacga cactcgtatc aaagcagcat tgccaacaat caactacgtt ctagaacaag
    78901 gcggaaaagc aatccttttc tctcaccttg gacgtgtaaa aacagaagaa gataaagaag
    78961 gaaaatcttt agctccagtt gcaaaacgtc taggcgaatt attaggtaaa gaagtaacat
    79021 tcgtacctga aactcgcgga gaacaattag aagaagcaat ccgcaacatg aatgacggcg
    79081 acgttgtcgt attcgaaaat acacgatttg aagatattga cggtaaaaaa gaaagcaaaa
    79141 atgatacaga actaggtaaa tactgggctt cattaggcga tgtatttgtt aacgatgctt
    79201 tcggtacagc tcaccgtgca catgcttcta acgtaggtat cgcttcaact ggtatcccaa
    79261 cagttgctgg attcttgatg gaaaaagaaa tcaagttcat cggtgaagca gtagaagaac
    79321 caaaacgacc aatgattgca atccttggtg gcgcaaaagt ttctgataaa atcggcgtaa
    79381 tcgaaaactt gattcctaaa gcagataaaa tcttgatcgg tggcggaatg acttacacat
    79441 tctacgaagc aaaaggaatc aagatcggta actctctagt agaagctgat aaagtggaac
    79501 tagcaaaaga attaatcgaa aaagcaggcg acaaacttgt cttgccaatc gacaatgtct
    79561 gtgcaccaga attttcaaat gatgttgaaa cacaagtaat cgaaggagac attcctgatg
    79621 gtttgatggc tttagacatc ggcccagcat cagtaaaatt atttgctgat acattacaag
    79681 gtgcaaaaac agttgtttgg aacggaccta tgggtgtatt tgaaatgagt aactttgcta
    79741 aaggtacaat cggtgtttgt gaagcaatcg ctaacttaga aggcgcaaca acaatcatcg
    79801 gtggcggaga ctcagccgca gcagcagaac aattaggatt tgctgacaaa ttcacacaca
    79861 tctcaacagg tggcggcgca agcttggaat tgcttgaagg taaagaatta ccaggactag
    79921 cagcaatcaa cgataaataa acgaccaagt ttgctcaatt ctgacgagta atcgaacaaa
    79981 aggtgaaggg agttttcatg actccctagc catttttcaa taaattaagg agtgtgttcc
    80041 tcaatgcgta aacctattat cgcaggtaac tggaaaatga acaaaactgc atcagaagca
    80101 aaagaatttg ctgaagcagt aaaaaacaaa atcccttcaa atgacaaagt tgattcagtc
    80161 atcggatctc ctgcattatt cttacaagaa ttaatgacat cagctgaagg tacagaacta
    80221 aaaatctcag cacaaaactg ctactgggaa aactcaggtg cgttcactgg tgaaacttca
    80281 ccagcagctc ttgctgatct aggtgttcat tatgtgatca tcggacattc agaacgtcgt
    80341 gaatatttcc atgaaacaga cgaagacatc aataaaaaag cgaaagctat ctttgcaaat
    80401 ggtatgacac caatcctatg ctgcggcgaa tctttagaaa cctatgaagc aggcaaaact
    80461 gctgaatgga tcgaaggaca aattacagct ggtttagctg atctttcagc tgaacaggtg
    80521 tcaaacatgg ttattgctta tgaaccaatc tgggcaatcg gtactggtaa atcagctgac
    80581 gcacaaatcg ctgacgaaat ttgtggagtt gtacgtcaaa cagttgaaaa actttatgga
    80641 aaagaagtat cagaagcagt tcgtatccaa tacggcggtt ctgtaaaacc agaaaatatt
    80701 gctgaataca tggcaaaaga aaatgttgac ggtgctttag tcggtggcgc aagcttgcaa
    80761 gcagattcat tcttgtcatt gttagacgct gtaaaataat tgttgaaaat ttgcgaaaaa
    80821 tgcaagaaat gtttgcacta atgagcaaaa ttaactaaaa tcgtatatga gggaaatccc
    80881 ttaggaaaaa acaaactcaa aggagagaca aaacatgtca attattactg atgtttacgc
    80941 tcgcgagatc ttagactcac gtggtaaccc aacaatcgaa gtagaagtat acacagaaag
    81001 cggagctttt ggccgcggaa tggttccttc aggtgcttca actggtgaat acgaagcagt
    81061 tgaattacgt gacggagaca aagctcgtta tggcggtaaa ggtgtaacta aagctgtcga
    81121 caacgtaaac aacatcattg ctgaagcaat cattggctac gatgttcgtg accaaatggc
    81181 tatcgacaaa gctatgatcg ctttagacgg aactcctaac aaaggtaaat taggtgcgaa
    81241 cgctatttta ggtgtttcta tcgctgttgc acgtgcagct gctgactacc tagaagtacc
    81301 tttataccac tacctaggcg gattcaacac aaaagtattg ccaacaccaa tgatgaacat
    81361 catcaacggc ggatcacatg ctgataactc aatcgacttc caagaattca tgatcatgcc
    81421 tgttggcgct ccaacattca aagaagctct acgtatgggt gctgaagtat tccacgcatt
    81481 agcttcaatc ttgaaagctc gcggattagc aacttctgtt ggtgacgaag gtggatttgc
    81541 tccaaacctt ggttcaaacg aagaaggttt tgaagtaatc atcgaagcaa tcgaaaaagc
    81601 tggctatgta cctggtaaag acgttgttct tgctatggat gctgcttctt cagaattcta
    81661 cgacaaagaa aaaggtgttt acgtactagc tgactcaggc gaaggcgaaa aaacaactga
    81721 cgaaatgatc aaattctacg aagaattagt ttctaaatat ccaatcatct caatcgaaga
    81781 tggattagac gaaaacgact gggacggatt caagaaatta actgacgtat taggcgacaa
    81841 agttcaatta gttggtgacg acttgttcgt aacaaacact caaaaattat ctgaaggtat
    81901 cgaaaaagga attgctaact caatccttat caaagtgaac caaatcggta cattaacaga
    81961 aactttcgaa gctatcgaaa tggctaaaga agctggctac acagcagttg tatctcaccg
    82021 ttctggtgaa acagaagatt caacaatctc tgatatcgct gttgcaacaa acgctggcca
    82081 aatcaaaact ggttctctat cacgtactga ccgtattgct aaatacaacc aattactacg
    82141 tatcgaagac caacttggtg aagttgcaga atacaaaggt ttgaaatctt tctacaactt
    82201 aaaaaacaaa taattctttt ctaatgaaga tacatgatcg actattgaaa gatagtcgag
    82261 tatgatcact tagttaagta atcgaactct ctacttgctg aaatatcagc aggtagagag
    82321 tttttttgca actagcttct gtatatgatg tttacaaaga atggtacaag aaaagatcat
    82381 ccttgaaaaa ggaaagctaa caataactag catcatataa gagcttttaa ggatagaaca
    82441 gtagaatagg aatctatggg caagtcctct cgtataaata aaataggagg gaagtagcag
    82501 catatttttc ataaagtggc tctctttctt catttttact ttggttgctc ctatttgaaa
    82561 attcgagcac actcaaatac aataaaaaga aatggcaagg gagaggatta gatgaaaaaa
    82621 gaagaaaaaa tcgcgatttt acaagagatt atccgaatta aatcagtgaa tggaaacgaa
    82681 ggtgaagtag cagcctattt gaataagctt ttggcaaagc atgacataac aggagagatt
    82741 gtttcttaca gagatggtag agataatttg attgctcgtt accaaaaggg ccaatcagga
    82801 aaagtgttag gcctatctgg acatatggat gtcgtggcgg ctggtgatga atcgtcttgg
    82861 acctatgcac cctttgcagc agaaatccat gggaaccgtt tgtacggacg tggtgctaca
    82921 gatatgaaga gtggcttggc agcaatggtg attgccatga tcgaactgaa agagtcagga
    82981 aaaccattta acggaacagt caaattatta gccactgtcg gagaagaagt gggtgaacta
    83041 ggtggggaac agctcacgaa agcaggctat gtagatgact tagatgcctt gatcatcgga
    83101 gagccaacca attacagttt gatgtatacg cacatgggat caatcaacta tacagtcacc
    83161 tcgcacggaa aagaagcgca tagctctatg ccagaccaag gttataatgc aatcaatcac
    83221 ctaaatgaat tcattacgaa agcaaatgct gaaatgaatc acctcgctga aacaatcgag
    83281 aatcctgtcc taggaaaaac aatccataat gttacattga tcagtggcgg gaatcaagtc
    83341 aacagcatcc caagccatgc gcagctccaa gggaacattc gatcgattcc agaataccca
    83401 aatgataaaa tcattgcatt gctgcaatca atcgtcaatg aattgaatca agagacagac
    83461 tatcatttgg aattgatgat cgattacaac aaaatacctg tcaaagctga tccagattct
    83521 cctttgattc attgcattca gcaacaattc agccagccat tacctttagt tggagcggca
    83581 gcaacaacgg atgcagccga atttacgaaa gctaaccatt ccttcgactt tgtcgtcttt
    83641 gggcctggtg tcgttacttt gcctcatcaa gtagatgagt atgttgaaat cgataattat
    83701 ttggatatga tcgaaaaata tcaaggaatt attttatcct acttagcgta agattttttt
    83761 aataaacgcc gtttgtataa ttaagcgaga caaataaaaa agccatttat gttacactcc
    83821 aattgtaata cccgctaaag catacaagga gagtgaacat aaatgactta tacccatctt
    83881 acaccaaacg agcttgtaat gatagaagca tattttcatc aagaaactcc ggttgctatc
    83941 gttgcgaagc agcttaaacg tggacgccaa acaatttaca atgtctataa ctttctcaaa
    84001 tgtggtggaa cagcacttga atactttgaa caatacaaag aaaataagcg acgttgtggg
    84061 ag
//
LOCUS       DAZKKZ010000003        82056 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.003, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000003 DAZKKZ010000000
VERSION     DAZKKZ010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 82056)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 82056)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..82056
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.003"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            28..909
                     /locus_tag="ACG8LA_000196"
     CDS             28..909
                     /locus_tag="ACG8LA_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HFQ0202534.1"
                     /translation="MAEIVKVTHLKKSFGRFEALKDVSFTVHSGEVVGFIGPNGSGKS
                     TTIRTLLGIIKKDGGTATIFGQDVWEDSLSIHERLSYVPGDISLWGNLTGGAIIDLFM
                     KLHGKGSAQKKDELIQRFSLDPKKKAKNYSKGNRQKVGLIAALAVDSDLYLFDEPTSG
                     LDPLMETIFQEEVEKLKEQGKSILLSSHILSEVERLADKVVIIREGTLDEEGTLDELR
                     HLTRSTITIETEAENSHLAQLNGVHDFVQKGHLAQFAADNEAFDVILAEASKLGVKKF
                     ESIPPTLEDLFMRHYEG"
     gene            922..2532
                     /locus_tag="ACG8LA_000197"
     CDS             922..2532
                     /locus_tag="ACG8LA_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFQ0202535.1"
                     /translation="MTDKFSRWSTLFSQNLSRDWKKILIWLVGVTAFSGGFVPAFEEL
                     TSGQGLAGLYETLQNPAMIAMVGPTPASNAAEYTLGAMYANEMLLFCSLFAAVISVLH
                     VVSQTRKKEELGLIELIRSFRVGRQANSLAVIAESILINLLLAISISCTMIFFQADSI
                     TAEGAWLFGLSVGSMGILGSAVALFAAQLMPSSASSNGLSLAFLGGLYLLRAITDVAD
                     SSLSMWNPLGWSYLTYPFTTNNWIPLLYLFLFSLILIISSFVLEEHRDLNTGYIPERE
                     GKPYAKRSLLSLRGLLFYLNKGMTISWLITFGLMGAAYGSIYGNMQQFLESNDLMKQM
                     FIQSGVSIEKNFTSTIMVVLICLAAILPIASINRLFTEETHGRMNQLFATKISRNQLY
                     WTNMLLAILFAILAILISSGALGLSALASMKDAKDMDLLMFLKAGFNFLPAVLVFIGI
                     SGFLFGWLPRIGKLAYIYLAYSFALNYFGGILDLPEWFSKTAVPSWVPRMPNDSFDLS
                     VFLTLSCISLALFVLGSIGYRRRDLLEG"
     gene            complement(2609..3268)
                     /locus_tag="ACG8LA_000198"
     CDS             complement(2609..3268)
                     /locus_tag="ACG8LA_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HFQ0202536.1"
                     /translation="MSHDHLCVSFVPLFNHLVQQDQEKVHALVKHHYVEKGEQILAPN
                     GEPQLVIVASGSMKVYQLSASGKEQLLRVIEPGGYEGESQLLGVPNESLFGEALEKTE
                     ICILRQKDFSELLLHYPALSLKLLAINVEKLTKVQQQTTFLMMEKVEERVAVYLLDLA
                     KATGKDHFFLPMKMKELAAFIGTTPETLSRKFKLLEENGYVKRKNREVWIIDKEQLED
                     L"
     gene            complement(3551..4216)
                     /locus_tag="ACG8LA_000199"
     CDS             complement(3551..4216)
                     /locus_tag="ACG8LA_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate 1-dehydrogenase family
                     protein"
                     /protein_id="HFQ0202537.1"
                     /translation="MELGKSDYQLFDRPIYAFKQLKESHPTDKIEQIKKEYKEHWQKW
                     KEIQLQTAALLPDMYGMSKPKIESWTNGWNLRSHFWSAYRSESRQDENACLAVLLNQK
                     QYQIYLMYQHYKSEERYGSIAAYNQLLAILKEWSKTVDIKDYYIWPQPEHELDDHLAL
                     SDYLSDTKKQEELKKAMRDRTFQMGKLFFYPQEIEHVEQITAETLQELAPLYQKLGAE
                     KFQ"
     gene            complement(4363..4968)
                     /gene="dhaL"
                     /locus_tag="ACG8LA_000200"
     CDS             complement(4363..4968)
                     /gene="dhaL"
                     /locus_tag="ACG8LA_000200"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047324 - phosphoenolpyruvate-glycerone
                     phosphotransferase activity [Evidence IEA];
                     GO_process: GO:0006071 - glycerol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaL"
                     /protein_id="HFQ0202538.1"
                     /translation="MKLTVQEIQEWLTQFAEAINQNKQYLSDLDTPIGDGDHGNNMGR
                     GVSAYEEAFQADHPETISDTFKVFSMAMISKVGGASGPLYGSAFMNMMKATKEVDSID
                     SQEKLGEVIEQGTAGIQSRGKAEADDKTMLDVWLPVTEALKAGNLTKEIIDQAKEHTK
                     VLVAKKGRASYLGERAIGHIDPGAASSAILFSTLLDVINQP"
     gene            complement(4996..6006)
                     /gene="dhaK"
                     /locus_tag="ACG8LA_000201"
     CDS             complement(4996..6006)
                     /gene="dhaK"
                     /locus_tag="ACG8LA_000201"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004371 - glycerone kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006071 - glycerol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaK"
                     /protein_id="HFQ0202539.1"
                     /translation="MPERKDGNKLKKIMNDPSNIVEEMLEGLVKSYPELVHRVESSRV
                     VAKNQKAEQVGLVSGGGSGHEPSHAGFVGEGMLSAAVLGDVFTSPTPDQIQTAIKEAD
                     SGKGVLLIVKNYTGDALNFDMAKELAAMDDIEVESVIVDDDIAVENSTYTAGKRGVAG
                     TVLVHKIVGDAARNGASLAELKELGEKVVQATKTIGLALRAATVPEVGKPGFELGEDE
                     IEYGVGIHGEPGYRREKMQPSKVLAKELVTKILDDYSNLPKEAGVLVNGMGGTPLMEQ
                     FVFMNDVLALLEERGVNVVFRKVGNFMTSLDMQGLSLTLIDLTETQWKDSLESNVQTI
                     SW"
     gene            complement(5981..6376)
                     /gene="dhaM"
                     /locus_tag="ACG8LA_000202"
     CDS             complement(5981..6376)
                     /gene="dhaM"
                     /locus_tag="ACG8LA_000202"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047324 - phosphoenolpyruvate-glycerone
                     phosphotransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase phosphoryl donor subunit
                     DhaM"
                     /protein_id="HFQ0202540.1"
                     /translation="MKKSILLISHSQKVTDGIKEMIEQMQKSEEVQIFSLGGINGEIG
                     SDPMKIVEAVNESSDAASYFVFADIGSAVLNSELAKDMLEEEQQQRYHLVDAPLVEGA
                     FAAAITAGITDDTQQILTEAQNAGKKGWE"
     gene            6530..6850
                     /locus_tag="ACG8LA_000203"
     CDS             6530..6850
                     /locus_tag="ACG8LA_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HFQ0202541.1"
                     /translation="MITTTTNSVEGKAVVAYKGIVFGEVITGIHAFKDLEAGLRNIFG
                     GRSKSYENELMGAREEALAEMAERAKALGADAIIGVKMDYEVLGSDNGMLMVTCSGTA
                     VSTR"
     gene            complement(6962..7819)
                     /locus_tag="ACG8LA_000204"
     CDS             complement(6962..7819)
                     /locus_tag="ACG8LA_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HFQ0202542.1"
                     /translation="MKKRMKPLIWPIAVSSIFLLGQTAFAETSEPAQTEPSTTISSSG
                     AENGASETEMTSNVPTDNSGETISSSEDTSINSSTSSDQIDHLQDLENKRKELEEALE
                     AAKNKLKEDQAAIDQDLADLKNKVGNDRAQLEKKLAEAKAKAEAVQTDLDGKIQQAKE
                     FNQQLNQVAQTASGKLSQTQADITAASQAIHGKISEAQTVANDFEAKKADLAASFQRI
                     KDILHSAGEKSVTSGSTTETVQQTTEPSKSTSQTLPKTNEKTASVSYSLAGAGVLVAA
                     AYGIIRKKK"
     gene            complement(7927..9231)
                     /locus_tag="ACG8LA_000205"
     CDS             complement(7927..9231)
                     /locus_tag="ACG8LA_000205"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFQ0202543.1"
                     /translation="MISITHTGNLFLDTCLSIMYFFLVSYPILGGFVWFIGVWCYVFL
                     YKHKQKEWVDVPLSVEPFITIMVPAHNEEIVIEYTIEYLMTKLNYHNYEVLVTDDGST
                     DQTPEILARLMKKYANLRVVRIEKNKGKAHAFNIGLAFAKGKLILSNDADTVPEPDAL
                     IRYVNYFIRPGARHIAAVTANMDVQNRTKLIAKSQTVEFSSIVGIIKRTQSAVFGGLY
                     AYSGANTMYRKEALIDVGGFRQDRATEDISIAWDHQLNDWLSVFAPEIIFFMEVPVTL
                     KMLYRHRKRWAKGGTEVWLTNFKKVMLHPFKHIGRTIIFIDQTLSIVWSIFFCISVVL
                     FAGLIGHYVYQGNYEQIYITFTFSFVFICFEMVAGFFQLLASLIVDDRRRKLKYLLFA
                     PLYMLLFWIVNAITIVTTFIPAVKTILGYGSGTWKSPERTKK"
     gene            complement(9228..9737)
                     /locus_tag="ACG8LA_000206"
     CDS             complement(9228..9737)
                     /locus_tag="ACG8LA_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202544.1"
                     /translation="MKKVTREEVASILVKDKYFSKGNYWLKIWQTLVALLGWMIVVLP
                     FIWVFFPLTRPERAKDFSLYAFLSEKKMLYFLIGFFVLIFFSFLITSFVLTRWNNRNL
                     YKKVNKSFEYEDEKLKKRQELLEEVYTERFGTKEERETVRFYSVSEEKNLDTTFIADL
                     YKENGVELK"
     gene            complement(9912..12047)
                     /locus_tag="ACG8LA_000207"
     CDS             complement(9912..12047)
                     /locus_tag="ACG8LA_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UvrD-helicase domain-containing protein"
                     /protein_id="HFQ0202545.1"
                     /translation="MVNTQKQLEEAYLKNVYQKLIDKKNELRESMDTAKIEGNQSLKE
                     MAGELRLNFDSYLDNLDTFSMIEMKNREIDQMNIKQKNAENQLAKIERLLKSPYFGKV
                     VVDFLDNEPKESFYIGTANFTDDADENLVYDWRSPIAELFYNNMIGPSSYTVRQNKID
                     TVIKERRQFLLERDRLVKFFDTSVAIQDDVLLEVLGQDETNEMKAITATIQSEQNTII
                     RDVKSQNILVNGVAGSGKTSAIMQRIAYLLYLYRDTMTSDDLLILSPNHRFIDYISNV
                     LPSLGERNPLNLTIIQLVSQLSAEEIEGEEAYFKRITGENVSEQTERLRSKKFIDNLK
                     QSDPLFLDHPNFIRGLTKNGKTVLSKKTIEKIYEKVPAHPKLIDRLQATKKALMSEWK
                     NHLLKQAKSPAVQNQVLSLTEDRQLELFGKLISDDSEQSIVAYARKLLQKKYRKITRQ
                     IEEMAWVDEHQLFERIYEKRYGSAYAWQPTRTVDEAVIILAIRHLLVEKVNVPAFRYL
                     LIDEVQDYTLAQLGLLIELFPKTHFTLVGDENQAIFNSSTTFADIMRCFDDYHLPIHR
                     YDLRNSYRSSGAITELFKTYAVDQEKIDIVSIRPQGKEPEYRSFRSSEELLKILAEIL
                     VSLKGEKAAVITQTEEETQTLQESIKKNSYGLENCQIIPLSLAKGLEFDHVILYPFEN
                     DGDEQRRRRQMYTAISRGMKSIVVLERAT"
     gene            complement(12130..13785)
                     /locus_tag="ACG8LA_000208"
     CDS             complement(12130..13785)
                     /locus_tag="ACG8LA_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HFQ0202546.1"
                     /translation="MKIVIVGGVAGGMSAATRLRRLMEDAEIVVFEKGPYVSFANCGL
                     PYYLSGEISERENLLVQTPESLSARFCLDVRPNHEVTAIFPENKTVEVVHEGQKHIEQ
                     YDALVLSPGAKPVVPSIPGITEADNVFSIRNVPDIDKVMHALEKQPKRAVIVGAGFIG
                     LEMAENLKRRGLEVMVIEQAPHILPTLDEEMAAFIEKELSHQGVEVITSHAVAGFEDH
                     GKRLRLDDGRTIPADLVILSIGVRPDNQLAVTAGIELGIRGGILVDERYQTNIPDIYA
                     VGDAIVVKQQITGKDALISLASPANRQGRQVADTISGISRRNQGGIGTAIIRTFGMTA
                     ASTGLSERTAKENELSFEVIHVSGKDHASYYPEATDILLKLIFHPETGEIYGAQGVGA
                     KGVDKRIDILATAIKGHLTIFDLPELELTYAPPFGSAKDPVNMLGYAAMNIAEGLSET
                     VQWHELPTELAKGKILLDVRTAEELEKGKFKEAKHIPLNELRDRLNELDSQQEYIVSC
                     HSGLRSYLAERILKQSGYHVKNLDGAFSLYQTVRPEELIYPNK"
     gene            complement(13787..14101)
                     /locus_tag="ACG8LA_000209"
     CDS             complement(13787..14101)
                     /locus_tag="ACG8LA_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HFQ0202547.1"
                     /translation="MNLLFQSIKSITVPELKEKLLENPALLDVRTPAEYRGGHIKGAK
                     NVPLQSINRYDGDKEKTVYVICQSGMRSKQAAKELKKSGYDVVNVRGGMNQWFDRTVG
                     GK"
     gene            14271..14531
                     /locus_tag="ACG8LA_000210"
     CDS             14271..14531
                     /locus_tag="ACG8LA_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HFQ0202548.1"
                     /translation="MEIDNKNILNRLKRTEGQIRGIQKMIEDEKECMDVITQLSAVRS
                     SIDRVMGMIVADNLKNCFEKPDSNPEEQAAKLEQAIKMIIKK"
     gene            14545..14859
                     /locus_tag="ACG8LA_000211"
     CDS             14545..14859
                     /locus_tag="ACG8LA_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsrE family protein"
                     /protein_id="HFQ0202549.1"
                     /translation="MKVVFHIDELEKWSETGKNVKNLIKASPETTIVVSVNGIAITGY
                     LDSANAEFLDLQGVVFHACANAMRANHISESSLPEQVIVVPAGVLDLVELQSQGYAYI
                     KP"
     gene            complement(15589..16143)
                     /locus_tag="ACG8LA_000212"
     CDS             complement(15589..16143)
                     /locus_tag="ACG8LA_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HFQ0202550.1"
                     /translation="MKLSTDWRKEIQTIPNLLSIFRIFLLPIYLYFVLRQSFYIAGAV
                     IVVSGLSDYLDGVIARRYNQVTDLGKVLDPFADKLTQLFLILSMAWYRPWLWLLFGLF
                     LIKEGFMFVAGLIGLSKNIKLSGAKWYGKVATAVIYVGMILLLLFPELPTLWVRVIFA
                     VITYGLLQSFVLYAVEYRKMFQRK"
     gene            complement(16269..18198)
                     /locus_tag="ACG8LA_000213"
                     /pseudo
     CDS             complement(16269..18198)
                     /locus_tag="ACG8LA_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336853.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
     gene            complement(18504..19220)
                     /locus_tag="ACG8LA_000214"
     CDS             complement(18504..19220)
                     /locus_tag="ACG8LA_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MIP/aquaporin family protein"
                     /protein_id="HFQ0202551.1"
                     /translation="MNSDMTQIMGEFIGTLILVLLGDGVCAAVNLNKSKAQASGWIVI
                     AFGWGLAVTMAVYISGFMGPAHLNPAVSLAMAMTGAISWNLVVPFIIAQVLGAFAGAI
                     LVWLSYLPHWNATKDESAILGTFATGPAIRNYPANVITELIGTFVLVLGLLAFGQNEF
                     APGTNVFAVGGLILAIGLSLGGPTGYAINPARDFGPRLAHAVLPIANKGTSDWAYSWV
                     PIAGPMIGAIIAVGVYSLMV"
     gene            complement(19221..21044)
                     /gene="glpO"
                     /locus_tag="ACG8LA_000215"
     CDS             complement(19221..21044)
                     /gene="glpO"
                     /locus_tag="ACG8LA_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004368 - glycerol-3-phosphate
                     dehydrogenase (quinone) activity [Evidence IEA];
                     GO_process: GO:0006072 - glycerol-3-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HFQ0202552.1"
                     /translation="MFSNKTRQDSIQKMQQEELDLLIIGGGITGAGVAVQSAASGIKT
                     GLIEMQDFAEGTSSRSTKLVHGGIRYLKTFDVEVVADTVGERAVVQSIAPHIPKPDPM
                     LLPIYEGEGATTFNMFSVKVAMDLYDKLANVTGTKYENYTLTPEEVLEREPFLKKEGL
                     KGAGVYLDFRNNDARLVIDNIKKAAEDGAYLVSKMKAVGFLYDGDQIVGVKARDLLTD
                     EVIEIKAKLVINTSGPWVDKVRNLNFTRPVSPKMRPTKGIHLVVDAKKLPVPQPTYFD
                     TGKQDGRMVFAIPRENKTYFGTTDTDYQGDFTDPKVTQEDVDYLLDVINHRYPEANIT
                     LNDIEASWAGLRPLLIGNSGSDYNGGDNGSISDKSFNKVVDTVSEYKENKVSRAEVED
                     VLNHLENSRDEKAPSTISRGSSLEREPDGLLTLSGGKITDYRKMAEGALRLIRQLLKE
                     EYGIETKEIDSKKYQISGGNFDPTKLEETVTELAKEGVAAGLEEEDATYIADFYGTNA
                     RRIFELAKEMAPYPGLSLAESARLRYGLEEEMVLAPGDYLIRRTNHLLFERDQLDEIK
                     QPVIDAIAGYFEWTEEEKAQQTKRLEALIAESDLRELKGEK"
     gene            complement(21058..22554)
                     /gene="glpK"
                     /locus_tag="ACG8LA_000216"
     CDS             complement(21058..22554)
                     /gene="glpK"
                     /locus_tag="ACG8LA_000216"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004370 - glycerol kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006072 - glycerol-3-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HFQ0202553.1"
                     /translation="MTESTYIMAIDQGTTSSRAIIFDKKGRHIGSSQKEFTQYFPQES
                     WVEHDANEIWNSVQSVIAGAFIESGIKPNQIAGIGITNQRETTVIWEKDTGRPIYHAV
                     VWQSRQSAGIADNLKNEGYQEFFHEKTGLVIDAYFSATKIRWILDHVEGAQERAEKGE
                     LMFGTIDSWLVWKLTDGQAHVTDYSNASRTMLFNIHQLDWDQEILDLLNIPRVMLPKV
                     TSNSEVYGYTQGYHFYGSEAPISGMAGDQQAALFGQMAFEPGMVKNTYGTGSFIVMNT
                     GEKPQLSKNNLLTTIGYGINGKVYYALEGSIFVAGSSIQWLRDGLQMLQKASDSEDAA
                     KRSTSEDEVYVVPAFVGLGAPYWDQAARGAMFGLTRGTTKEDIIKATLQSIAYQVRDI
                     IDTMQDDTGIKIPVLKVDGGAANNEYLMQFQTDILNVPIQRAENLETTALGAAFLAGL
                     AVGYWKDTDEIREFYEAGKLFEVQMEEERREKLYNGWKKAVKATQAFE"
     gene            complement(22690..24150)
                     /locus_tag="ACG8LA_000217"
     CDS             complement(22690..24150)
                     /locus_tag="ACG8LA_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0202554.1"
                     /translation="MKIEALLERKEQLQILILRNLVLQGGTASINGLREHVQLSKASF
                     DQYLEDIELIGRMMEKKVEVQRNEYQALLVLDEDVSLEKILLFLLQESLKFKMLVYLL
                     EHQQVSIVRLATAFNISESSVFRKIKELNQLLEEFGLQIKNGQLYGEELQIRYFYYEL
                     FQYIPEDQRPLFLQNTPEKRPFILGLDRVLETTFTASAEAQIACWLGITKKRLLNEKS
                     TYATLKEKKLLYQSDRLYQAIDPIIVMHLSRTAAELNVYETMMFYSFFVSFSIVDEEI
                     FYQYDLTRSKKLPTAVLDTYIRETMLWHYRPRRLKIKEEKAVGYQISQINNEWFFFVG
                     KIEVYERDRLLEQQQKMLGHSLTQLLAKLQETAVQQLPRKRAEDSELSYLMIQYANVL
                     LMIDFYIAKPVVIGIDLESLPIYRIAFQQYLIRELRGIGGIEIGSYEEGKEYDLVITF
                     CQRNKKQCEYYLSEFASPYDIIRLKRRIETLKKEKN"
     gene            complement(24140..25435)
                     /locus_tag="ACG8LA_000218"
     CDS             complement(24140..25435)
                     /locus_tag="ACG8LA_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HFQ0202555.1"
                     /translation="MNIVIVGGSFAGIHAAIYLRQLMPTSEIYLIEKQSKLGWIPSGF
                     NLILKGKVTSEKQLSWITKEELTDRYRIHVYTEKTVIGLKEKKVVLAGGKKLDFDRLI
                     LATGSNQKFRNISAESTLIHPVKKIQNVTALQQKIMNAKKIAIIGAGQAGIEIAEGLA
                     SRKKQIHLYESRKSILFRYLDPEMTEPLVKEMKNQGLSLFLEEQVVSLTENETAIVET
                     EKRKENYDLVLLANHSRPDNQMWEEQLTLNDDGTIWVDDYLQTSQKDVYAIGDAIQVT
                     FRPTNEKMYVSLVNNAVRTARNVSKTISGSQTKDQGTYRPVGNQWFGYFLGSVGLTEE
                     ESIFYPQKIETGYVDYKLTAINQSKVKLKFLFDSEKKILGAQLQSKKEMFHLLDQLTI
                     AVEEGWTFEQLEEHELFFQPEYRVPDMVWSKVANTAYED"
     gene            complement(25767..26444)
                     /locus_tag="ACG8LA_000219"
     CDS             complement(25767..26444)
                     /locus_tag="ACG8LA_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0019172 - glyoxalase III activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase
                     domain-containing protein"
                     /protein_id="HFQ0202556.1"
                     /translation="MKVLIVLTNVEKYEKIERPTGLWLSELTHFYDVLVKNGIDADFV
                     SPKGGYVPLEPQSVLNMDEIDWAYYEDEDFRNRALGNTLRPDDVDANDYAAVYYAGGH
                     GTMWDFPEAIDLGKVASQIYRNEGLVSAVCHGVVGLLPVTDESGKSILAGRTVTGFSN
                     EEEEANGTTNEVPFLAEDALKEKGANYQSGAAFSEVVQIDGRLLTGQNPQSAHQLGEA
                     VVEALKN"
     gene            complement(26474..27565)
                     /locus_tag="ACG8LA_000220"
     CDS             complement(26474..27565)
                     /locus_tag="ACG8LA_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-dependent flavin oxidoreductase"
                     /protein_id="HFQ0202557.1"
                     /translation="MSQFDQSITLPSGVQLKNRLMLSPMTTQLSFFNGVITEDEITYY
                     KQRSKGLGAVITGAANVQDIGKGWPGELSIAHDEMIPRLSELAKAIQGEGAKAIIQIF
                     HGGRMTSRATLSGEQPVSASAVAAKRPDAETPRAMSEEEIVETIQAFGKATRRAIESG
                     FDGIELHGANTYLIQQFFSPHSNRREDQWGGSLENRYRFIEELLTTVFSAVEQYAKKP
                     FIVGYRFSPEEYETPGIRFEDTIWLLERLRESKLDYLHVSLNMYDRIARSDKYNDKSI
                     LEVVHNTIQGKIPLVGVGGIRNREDVEQVLKYAELAAIGQQMIVDPDWAEKLLENRED
                     EFVTKPFEEAYKELYLPSPLYNFLKARYQ"
     gene            complement(27666..28100)
                     /locus_tag="ACG8LA_000221"
     CDS             complement(27666..28100)
                     /locus_tag="ACG8LA_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HFQ0202558.1"
                     /translation="MEKPIEKALDECLFFSVKKLDRMLNKLADEAFRRTGLAPTYGFI
                     LLILKEKDGIPQKDIAQMLYSAPSTIARFVEKLEYKGYVKTVSEGRLSLVYLTEQGRQ
                     FAKEVDGSWEELHQSYKAVLGNEASKELAQTMNDATDKLQKK"
     gene            complement(28684..30141)
                     /locus_tag="ACG8LA_000222"
     CDS             complement(28684..30141)
                     /locus_tag="ACG8LA_000222"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFQ0202559.1"
                     /translation="MKKFPEGFLWGGATAANQCEGAWDVDEKGLSVSDVYTFDSDLPK
                     EKWTDQWHMMTHQQVKAAQDPNSKYYYPKRHGNDFYHHFKEDIRLFAEMGFKCYRMSI
                     AWTRIFPHGDEETPNEAGLFFYDQVFDECLKYGIEPVVSLSHYEMPLYLVTEYGGWPN
                     RKLIQFYVRFAETVFKRYKNKVKYWMTFNEINCVKHHPFVSVGVIEENHPHLEQAKYQ
                     GAHHQFIASALATKACHEIIKGSQVGCMISYQLLVPYSCDPDDIQKTIEQQRTSLFFS
                     DVQARGYYPAYTQRMFEEKGVNLKIEVGDEEILAAYPVDFVSFSYYMSSAVSAHPENW
                     EGVQGNLITGGIKNPYLPSSEWGWQIDPKGLRIALNQLYDRYQKPLFIAENGLGAIDK
                     VEEDGTVQDDYRIDYLKQHIEQMKEAIKDGVDLFGYTSWGCIDIVSASTSQMSKRYGY
                     IYVDQDDEGNGTKKRLKKKSFDWYRQVIQSNGEIL"
     gene            complement(30138..32033)
                     /locus_tag="ACG8LA_000223"
     CDS             complement(30138..32033)
                     /locus_tag="ACG8LA_000223"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HFQ0202560.1"
                     /translation="MEKPFSKNYTYLVRRIATALINKGEVKMDYSQLAKDIVRFVGGE
                     ENVSNVYHCATRLRFTLKDNKKADKEKVEQLEGVITVVEAGGMFQVVVGNAVNEVYDV
                     LSKQMKLEDDASSGKRGTEKKGILNSFIDMIAAVFAPTLGVLAGSGLIKGVLALCTSL
                     NLLTTESGTYIILNAAADAFFYFLPIFLAYTAAKKFNTDRFIAMVIAAALVYPTIVSA
                     YSDSITLRFLGMPVILARYTSTVIPAILAVWVLSYIEPKIRKSLHESIRNLLTPFICI
                     IVMVPIILLVVGPIADYASQLIAAGYLAVYNFSPVLSGAVIGGFWQVLVIFGLHWGLV
                     PVMTNNLSFYGRDTLGPACMTAVAAQAGAVLGVFLKTKNKKVKSLSLSAFITALFGIT
                     EPAVYGVTLKYKRPFYIACICGAIFGGVAGAAGAGALAVATRSILSFPIYIGEGFVWL
                     VASYFLAMISSCMLTFLFGYKDEIEEESSKDIVLSTPAAGEIIDLSEVNDPTFASGSL
                     GEGFAIIPTDGKIYSSVNGEVSTVFPTKHAIGVVSEEGAEILIHIGIDTVNLNGKYFQ
                     SAVSDGKKVRKGDLLMEVDLQELIKEGYDPTTMVIVTNSSRFKNIITSHKKNNQTRKL
                     ASLGGSI"
     gene            complement(32091..33866)
                     /locus_tag="ACG8LA_000224"
     CDS             complement(32091..33866)
                     /locus_tag="ACG8LA_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HFQ0202561.1"
                     /translation="MFITKRRCKQMDLNKRQLQILVVLRNKNHWITSEELAEALGTNK
                     KTIQTEIKNMLAIYEKKIIIQSNKRSGYFLESIESETKQQIIQEVTKHKIYSSMDFRA
                     STIVTYLLFQKGYVSMQKIADIFFLSKTAVSLQIKTILRWIERNPKLELEVSSTKGLK
                     IIAEENSKRIFLSLVGTETVIQHARFPQQISTIFSNIMPTVQKTLKEVLISYNYIVSG
                     EDFIRFSRYLVLTILRREELLEKTNRYTLFIPMVETLTKKLSSELPYSFSNQEKQAIE
                     NRLLELNYLMINDEKNKEIEKNLRAFEQTIIRFLDLPVSLLFHETEFLLTHIKQMKTR
                     MDAGHNTMNHFVQKIISRYPLEIYLIRRFFPIHFQLRPNLAESAYFVLYLAEALNPFR
                     KQGEILIVSNQPISILNTLKKQIQQSMNMWIKECRIEPVYLFKNQSNKITEYDAILTT
                     EQELIFEWDDLIYLPSVLDEFESWEIYQILREKLTIVEEKKKTKLLDHYYKEENQIKI
                     HKKIDSIQQLISPSSDLVMLPLNAETLLCCLIKSQVETKITEYQLEIPLIHQQRKIKR
                     VFFVSFDYKRNDILVFFQAVSDLLG"
     gene            complement(33916..35412)
                     /locus_tag="ACG8LA_000225"
     CDS             complement(33916..35412)
                     /locus_tag="ACG8LA_000225"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFQ0202562.1"
                     /translation="MDQEIFPENFLWGGAVAANQCEGAWLEDGKLPNVTDTLIGIMNQ
                     HPSIQWNEEKKIWEIALDESLHYLSHEAIDFYHRFEEDIRLLKELGLKAFRTSISWAR
                     IFPRGDEQKPNEAGLVFYDRLINTLNRYDIEPVITLSHYETPLALVGEYGGWQNRKLI
                     DFFEFYAQTVFERYQGKVKYWMTFNEINNAFRMPYAAAGLVTFPARDKLEPIATLTKK
                     VIYQACHHMFLANARATQLLKKIDPNAKMGIMCSFSALATYAYDCDPENVFGSLQFKR
                     NSWFFSDVMCRGHYPAYIYRTWKEEDCAPVMLDGDEQCLQANTADYIAFSYYRSAVYK
                     KEAEMRVDTGGANGFDNPFLKEKSPEPWSWPIDPLGFRYVMNELTDRYELPLFIVENG
                     IGLDEAPDELNRIHDPKRCEYLKIHLQEIAEAIKDGCQIIGYLWWGPIDIVSAGTGEM
                     RKRYGFIYVDRQNDGSGSFRRLKKDSFEYYKQIIQSNGKNLEYRSFFK"
     gene            complement(35606..37228)
                     /locus_tag="ACG8LA_000226"
     CDS             complement(35606..37228)
                     /locus_tag="ACG8LA_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HFQ0202563.1"
                     /translation="MEQKWWHHSVVYQIYPRSFQDSNQDGIGDLRGIISRLDYLAYLG
                     IDAIWLSPVYESPNDDNGYDISNYQAIMAEFGTMEEMEELIEEAKKRNIRIIMDLVVN
                     HTSDEHPWFIEARKNKENPYRDYYIWRDPVNGKEPNRLRSIFSGSAWQLDEKTGQYFL
                     HLYSKRQPDLNWKNKQVRQEIYQMMNFWIDKGIGGFRMDVIDMIGKEPDKEITSNGPK
                     LHEYLQEMNQATFGDKNLMTVGETWGATTEIAKLYSNPKRNELSMVFQFEHIGLDQQE
                     GKDKWDLKPLSISELKKVLSKWQTSLGDEGWNSLFWNNHDLPRIVSRWGNDDVYRKES
                     AKMFAILLHMMKGTPYIYQGEELGMTNCPIDDIAEAKDIETINMYNERISSGFTKEEI
                     LESIKAKGRDNARTPMQWNAREHAGFTTGIPWLRVNPNYKEINAEEALADQDSVFYMY
                     KKLIDLRRKHDIIVWGDYELVEKTPEHVFAYSRIYEDQQWLVICNMSSEKQTFTIPRE
                     ALRVIVSNYPLKQLPDGKVDLRPYEAFVLEVK"
     gene            complement(37556..38869)
                     /locus_tag="ACG8LA_000227"
     CDS             complement(37556..38869)
                     /locus_tag="ACG8LA_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HFQ0202564.1"
                     /translation="MKEKILSYFEIEKLNTTVKREVLAGFTTFISMAYILFVNPTVLG
                     ASGMDEGAVFTATALASAIGCVLMGVLARYPIGTAPALGINAFFAYSVCLGMGIPWET
                     ALAGVFVASLIFILITIFKLREMIIDAIPADLKYAISGGIGLFIAFLGLSEGGIIVSN
                     ESTLVGLGSLNVGSTWLTIFGLVVTAILLVRRVPGGIFIGMAATTILGLVTGLIPMPS
                     EIVAAAPSLKPTFLVALKHVGDINSLQMWVVVLTFLLVTFFDTAGTLVGLANQAGFMK
                     DNKMPRVGKALASDSTAMLAGSLFGTSPVGAFVESSAGIAVGGRSGITAITTGIFFLL
                     GLFFSPLLSVVTSQVTAPALIMVGVLMAQSLRQIEWGNLEIAIPSFLILIGMPLTYSI
                     SDGIALGFIFYPITMLAAKRGKEVSPIMYGLFFVFVGFMWILNVK"
     gene            complement(39114..39338)
                     /locus_tag="ACG8LA_000228"
     CDS             complement(39114..39338)
                     /locus_tag="ACG8LA_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202565.1"
                     /translation="MDLMGRLEGYLKYRRAKHSEKLRAKNLKSGKKKTKGWGKMVDTG
                     FGGLNNLNPVDTKEFIKEEQKRNGKIKSHY"
     gene            complement(39358..39780)
                     /locus_tag="ACG8LA_000229"
     CDS             complement(39358..39780)
                     /locus_tag="ACG8LA_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFQ0202566.1"
                     /translation="MESVYRQERKSNRKKGQMMIQKTRVMLYVNDVEMICRFFVEKIG
                     AEISETIELPEEFKSIVLSISKELELGVFPKVFVQKFSPEVLGPPPSLVFFTDEFETI
                     YENMEEPGEITDNNGILTFNFSDPEGNYFVIGKAESSD"
     gene            complement(39922..40632)
                     /locus_tag="ACG8LA_000230"
     CDS             complement(39922..40632)
                     /locus_tag="ACG8LA_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase beta subunit-related
                     protein"
                     /protein_id="HFQ0202567.1"
                     /translation="MKKVIVDTNFWEVFPEATIEILSVNGIDNHVTKESEETYHQLLN
                     EAAKEARNYLTEETFSQNEVIAQWRQAFTTFKTKKGARSSIEALLKRANQEREFFPIN
                     PLVDIYNSISLSFGVPCGGEDIEKIAGNLHLGKAQGGESFLPLGADSDAPALPEEIIY
                     YDEQGAICRCLNWREAQRTMLTEETQAAVLVIESINAEQAARGAQAIEALKEKIDQTF
                     GVTSVRHTLTKDESEAEL"
     gene            complement(40650..41147)
                     /locus_tag="ACG8LA_000231"
     CDS             complement(40650..41147)
                     /locus_tag="ACG8LA_000231"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFQ0202568.1"
                     /translation="MTPSDVDLLQQISIETFTDTFGKDNSPEHLADYLTQAYALEKLT
                     EELKDKETDFFLVSIDQEPAGYLKLNTGTSQSEEMADHFLEIERIYVRKKFKHQGIGT
                     FLLDTAIEKAKEKQKTAIWLGVWEHNDVALAFYRKKGFIKYSEHVFYMGDDPQTDYLF
                     IKQLF"
     gene            complement(41184..41636)
                     /locus_tag="ACG8LA_000232"
     CDS             complement(41184..41636)
                     /locus_tag="ACG8LA_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HFQ0202569.1"
                     /translation="MAEILRDIGMIARALDSISNIEFKEVDLTRGQYLYLVRICENPG
                     IIQEKLAEMIKVDRTTTARAIKKLESNGMIERLEDKENKKIKKLYPTKKGAEIYPFII
                     RENNYSNAVALNGLSDEEAKQLEYLLNKVCKNVSEDWNFVKKGNKRIY"
     gene            complement(41771..42376)
                     /locus_tag="ACG8LA_000233"
     CDS             complement(41771..42376)
                     /locus_tag="ACG8LA_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HFQ0202570.1"
                     /translation="MNKKLAQYKRLLALSQAGLYYGKDVFDKERFEEIRTISLELISE
                     IGKETFEEIKALTTIGEGHPTPKVDVRAYIKKDGKVLLIEDKRTKEWSLPGGFAEIGL
                     SPEENVRKEVYEETGLTVETTQLRAVFDTNKQKDIPQLFQYYKLVFACAIHGEEAKFI
                     ENNETSNMGFFSIEELPKLSEKRTTKKQLLILENKNQIYCD"
     gene            complement(42826..43446)
                     /locus_tag="ACG8LA_000234"
     CDS             complement(42826..43446)
                     /locus_tag="ACG8LA_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFQ0202571.1"
                     /translation="MKKYFILLAGSPGTGKTYLMNKLRERFPDMYAITLDEIKEYYAE
                     SIGFNNLEERAEQERTKVYPFYYKALDLYMEAGKKVIVSEYPFSDKQKARLQELADRY
                     GYQVITIRLTADFEVLWQRRYKRDRESDRHLSYIMDHYHYGDVLEDRTKGTNHITKEA
                     FKKIIADRKYDKFQLGTLYEFDVTDYTQVDYTPLLDKLEKEINDNK"
     gene            complement(43448..44317)
                     /locus_tag="ACG8LA_000235"
     CDS             complement(43448..44317)
                     /locus_tag="ACG8LA_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HFQ0202572.1"
                     /translation="MYTTLKEVTKTAEELNFTVGAFNTHNLEMLPAMLGAAKEMGSPI
                     IIQTSVDTAKYIGMHVLVNVMTAIAEEEMVDAVLHLDHARDFDDIKEAIDSGYTSVMY
                     DGSHLPFKENILKTKAVVEYAHAHGVSVEGELGTIGGTEEGIHVAENDKVYTRPEDAV
                     KFVEATGVDALAIAIGTNHGQFKSKTEVNIPLLKEIDAVVDVPLVIHGGTGVKEEDYP
                     ELINNGIRKFNVGTELLVNWTKVAKETFSETEINKSLRHNVIPANEAVKEIVKHKIGL
                     FMNLESPINLGNK"
     gene            complement(44340..44747)
                     /locus_tag="ACG8LA_000236"
     CDS             complement(44340..44747)
                     /locus_tag="ACG8LA_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HFQ0202573.1"
                     /translation="MFGFFKKKEKEPKKVLAKEEKALSPEATEKIQSEITQLKQEIST
                     TQDKHKLAKLYEQVGLKFSELYVNDQAIQYLEKSLENKQTIGDGYKKLMSLYNQKRAD
                     AARAGDDQGIDYYMGKMDEMRQIAKQVTIKGNK"
     gene            complement(44766..46055)
                     /locus_tag="ACG8LA_000237"
     CDS             complement(44766..46055)
                     /locus_tag="ACG8LA_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HFQ0202574.1"
                     /translation="MGVINFIIENILTQASITIALIAMLGLLLQKKSAGQVISGTLKT
                     LLGFQVLSAGSSIIVGSLTYFGKIFTEGFHMQGIIPSIESINGQAMNDLGLGRDIALT
                     FLAIFVFNIILARFTKWKYIFLTGQAILWMATMTTVFGYFAGLRGIVLILVGGFIGAC
                     FAIAMPAVAQPIIRKITGSNDIALGHFCTIGYLFEAGVAKLFGEKGENKKSIEDIKLP
                     THFEFLQDTYLSVMVVMVPLYIITVLFAGEPFASELSGDQNYIMFAFLQAIQFVVGVY
                     VLLAGVRLLLGEIVPAFRGIAMKLVPDAIPALDCPVFFPYSPNAVILGFITTTIGTII
                     AMFTLPMFGLAMILPGMLTNFFAGGTAGIFGNAVGGRRGAIIGGIAHGFFITLLPALL
                     VTIFNSMGFNNATATDVDTVAAALLYAWILSPVLKAF"
     gene            complement(46082..46384)
                     /locus_tag="ACG8LA_000238"
     CDS             complement(46082..46384)
                     /locus_tag="ACG8LA_000238"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFQ0202575.1"
                     /translation="MNKLNILFVCGAGLGSSFAAQMSAEDVLNKLGVEAKLDHCDISS
                     AVSMKPDVIITAENFRSQFEKFAVDPKTAMIYLKNIVSKNEIEEKITPVLQDKGVI"
     gene            complement(46409..48502)
                     /locus_tag="ACG8LA_000239"
     CDS             complement(46409..48502)
                     /locus_tag="ACG8LA_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HFQ0202576.1"
                     /translation="MKTRTIEILHRIMTAQYPVKAKHLASEFNVSQRTIRQEVLEANI
                     WLSSKKLPEIRTIRNKGFLLKLEKEKQARLETEIKDVKDGFLNRRERIFDLVLAVAYS
                     RIPIHLNKKEEEFQISKSTLDEDMRRLRATLVSYGIEIVSYGKQGLVYKGSERSIRTM
                     IYDFINQNLGMTDFFMNQDAQLTPAQKIFLHYFPLVEIKKIQEIYSNKLLKQEDDIYK
                     KQILLFTLIWIQRIRKHEFISAINWKNTEIKDSSFSAFIDHMIEEFQLDNVPQVERNY
                     LRFTIETFNARDISNSIEWVQAQLLTIQLIQFVENETHVPFHLKEEALFENLYKHMAA
                     LIVRIKNHIQVMNPLKENIRTNYFPIYRAVTHFVPTIEEVIGGKILEDEIAFLVIHFS
                     TIASVIKRDLNYVYKSVVVCNHGMATGNLLAENLKEKFPQIEITAVLSSKEIELVDKL
                     DVNLVFSTFQLNYRNKPLLVVDPILTETNILVIEDFLKRNEELQRLEPNSHESTELFT
                     QIIDVMKESGGRVDRIIYGKLEKLFETNNLEINKREIQPMLKDILTDSNIMIKEKATT
                     WEESIELAARPLVKENIVEERYVEAMIRAVNDYGPYIVIGKHMALAHARPEDGVNKLG
                     VSVATIEQPIDFGNPEMDPVKIIFCLAAVDSYSHLNIMKELIELINNEEKLDRLIECT
                     NIEDFKQLLFSVVEK"
     gene            complement(48991..49755)
                     /locus_tag="ACG8LA_000240"
     CDS             complement(48991..49755)
                     /locus_tag="ACG8LA_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIM44-like domain-containing protein"
                     /protein_id="HFQ0202577.1"
                     /translation="MKKINYLAIILLVGLCLFALPTQGFAVAGGHGGGTSSGRSSGRG
                     SFGGRSYGGSYFGSRSYGRDSYGYYGPGTGPSSYEQTGFLALAVLSVGGVSAFSIVKN
                     KRQKKRLKAEILSRMSGTAKEKKAQFLEIQKIFMKIQSAWEEETPEKARSCYTDKLFA
                     EHQKVLQKNKADGVRNHTKKITIQEVGNYRQIHENSFAIRIDFRCCDYSVDRKDGRLI
                     SGSKTQRQYFSQIWYFDFSEKEKRWQADFIQPIMLD"
     gene            complement(49866..50735)
                     /gene="mdcB"
                     /locus_tag="ACG8LA_000241"
     CDS             complement(49866..50735)
                     /gene="mdcB"
                     /locus_tag="ACG8LA_000241"
                     /EC_number="2.4.2.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046917 - triphosphoribosyl-dephospho-CoA
                     synthase activity [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA];
                     GO_process: GO:0019361 -
                     2'-(5''-triphosphoribosyl)-3'-dephospho-CoA biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase MdcB"
                     /protein_id="HFQ0202578.1"
                     /translation="MINDERKKAVTQQLAALVEEALIAEVTLSPKPGLVDALDAGAHS
                     DMDYALFLKSAKTLTPFFEEMAQIAWHHAIDQELRERIAEIGRKAEKAMLIATNGINT
                     HKGAIWAMGLLISVIAQKISMEQPFSLSKILDDVSKLAAFPDTKYRHKKTTHGHRVKQ
                     KYGVNGAYEEAILGYPHIRLAIQAAKELDNDSYVQKQMHMLLVLMSSLDDTCVLHRSD
                     QKTLVEMQKLAHAASQSALPNRPFTALLHFCQENQISPGGSADLLSASLFMLKIEELW
                     TADTYICPMLLND"
     gene            complement(50760..51836)
                     /locus_tag="ACG8LA_000242"
     CDS             complement(50760..51836)
                     /locus_tag="ACG8LA_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HFQ0202579.1"
                     /translation="MFENKKIKINVSDFQKVSAVTAVMMQTILSFALANSHSATNTAF
                     LGTFYVIVKYTAPMFIFAIVYNMVKTSQHLSYWEFLKEKFFELVVPYLLWTTAYLWLF
                     PAVQQQTPYTDTASFLLKYVTGDGAPHLWYTVMMLQIQLFMPFFVWLGYKVFANKKYV
                     WPVLIGSTILYVAWYLFYQTQVLTGPYHDSWYLLDRFVASFMIYGVAAFVYHEKVYQY
                     LDRVRYLFLPVALVIAFFSVRSLLAHPGDLSFANAPYLNTIQSLYSLVIIFAVFIGAS
                     KMIVNDSPKLPLFKWLSVYAYRTYLANVFVFQVLLLLFKDSWLQLPSGVMILVAYLMT
                     ASCAFALSWLLHIIWVAIKKGFSK"
     gene            complement(51860..52453)
                     /locus_tag="ACG8LA_000243"
     CDS             complement(51860..52453)
                     /locus_tag="ACG8LA_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase holo-ACP synthase"
                     /protein_id="HFQ0202580.1"
                     /translation="MIQAHDIVLFDKHEIEGFTLPEWVVLTEKMFGTVRRASTDHAEI
                     LPIGLRGPARNQRWSTEISKHAVKQVIHPWDIIEQESYRQEKIMDYPVYQQFHAARNI
                     LSGCKWGIGGSLGFELSTGIPAVKETSDFDLLLYANSPIELPIQVIQSHPAFFEQFDT
                     QVVTRQGGFSLKEYLREPEKKILLKTVEGPKLTKELW"
     gene            complement(52457..54133)
                     /gene="mdcD"
                     /locus_tag="ACG8LA_000244"
     CDS             complement(52457..54133)
                     /gene="mdcD"
                     /locus_tag="ACG8LA_000244"
                     /EC_number="4.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="biotin-independent malonate decarboxylase
                     subunit beta"
                     /protein_id="HFQ0202581.1"
                     /translation="MKNSFVELNARERVNALLDNGRELIDPFDQIIAPSLPAQGIVPE
                     SDDGIVVSRGTINGKQAVVIAMEGKFQGGGIGEVSGAKIVAALEHVLEENKKGNEIFP
                     VIVLDTGGVRLQEANYGLLSISEIGNVIIALKQYVPVIGLIPGRVGSFGGMSITSALM
                     SYLIATKKARVGLNGPEVIEQEAGVREFDSSDKDLIWNTLGSRQRVESKIIDELVTDS
                     VEAIKAAVIAAMDERKDTHRSESSAFYLSLLDSLDLSKPMAIDDYNEAIANHQAKSID
                     LPEVAEGNEPAAASVGYDWFAALTGMKNPTSSISTVYYGKSSKFIEEAIVTSIVPDPK
                     NPMYRVRNGEVGLVEGFRMGQILDHVYEEDKDKKVKRPIIVVIDVPSQAYGYNEELIG
                     IHVALANSAAAYAKLRQAGHPVIGLIAGNAISGAFLAHGLQSSRLIALNNKEITVQAM
                     SKESAARVTKRSVAEIEAAAEKVPAIAYDINNYTKLGAIYHFLEDITDQAASEQNVSK
                     VIEAINEAIQDVRNTNDTMLTNRYTNETAKTFGRVETNKVRAKMDEEWDA"
     gene            complement(54123..54422)
                     /locus_tag="ACG8LA_000245"
     CDS             complement(54123..54422)
                     /locus_tag="ACG8LA_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit delta"
                     /protein_id="HFQ0202582.1"
                     /translation="MEQLAYKYPTKQPINKKIHVGVVGSGDLEILMFPTEKTESTVKI
                     CTGSDGFGEVWNNVLTRFFDRYPISADIVINDFGATPGVVYLRLTQAMEELSDEK"
     gene            complement(54524..56170)
                     /gene="mdcA"
                     /locus_tag="ACG8LA_000246"
     CDS             complement(54524..56170)
                     /gene="mdcA"
                     /locus_tag="ACG8LA_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010748322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015451 - decarboxylation-driven active
                     transmembrane transporter activity [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit alpha"
                     /protein_id="HFQ0202583.1"
                     /translation="MEKPNRNWASKREKKAQRLEKISNLLNGKYVETEKIVEVMEKLI
                     APGDKVVLEGDNQKQASFLSESLEKVDAEKVNDLHLIMSSISRPEHLNIFEKGIASKI
                     DFSYAGAQSLRVAQMIEDGTMKLGDIHTYLELYGRLFIDLIPNVVLVAADKADKDGNL
                     YTGFNTEETPTIIEAAAFKDGIVIVQVNEVVDSLPRVDIPGDWVDVVVKADKPYQLEA
                     LFTRDPQNITELQILMAMMAIKGIYAEHGVQSLNHGIGFNTAAIELLLPTYGESLGLK
                     GKIAKNWVLNPHPTMIPAIESGWVESIHSFGGEVGMEKYIAARPDVFFVGKDGTMRSN
                     RTLSQAAGQYAIDMFIGSTLQLDYEGNSSTVTKGRLSGFGGAPNMGHNPGGRRHSTPA
                     WQSLRDNDDPLGKGQKLVVQMVETYGSNKKPVFVEELDALAVQKQAGLANAPVMIYSE
                     DTTHIVTEEGIAYLYKAKTKEERQAAIAAIGGVTPLGMTSTKESLDSLRAAGIVKLPE
                     DLGIKRSEAKRSLLAAQTIDDLIEWSDGLYEPPMKFRTWS"
     gene            complement(56177..57088)
                     /locus_tag="ACG8LA_000247"
     CDS             complement(56177..57088)
                     /locus_tag="ACG8LA_000247"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004314 - [acyl-carrier-protein]
                     S-malonyltransferase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HFQ0202584.1"
                     /translation="MSTGFLFPGQGSQKLGMLADIPEMYMERLENVTGYRLVDKEENY
                     QDTVFIQLALLTKAVFYLDEMEKNGIQPDIAAGHSIGAFCAAVACRSLRFENAAELVY
                     HRAVLMKEAYPSGYAMGVVVGVTRSEAEEIVAKTFDPDHPVYLSNENCPMQHTLSGSI
                     EGLSVTLAEAKRHQAQTAKLLKVPVPSHCLLMNDTVKKFKPYMQSVHLSDARCLYIKN
                     TDGRATQDAEEIRKDLLENLAFPVQWNQMMDLAKELGMDLTIEFPPGNTLTKLIHTKF
                     GVDKGIRTINLDQHGIDDATFLYQKWR"
     gene            57208..58065
                     /locus_tag="ACG8LA_000248"
     CDS             57208..58065
                     /locus_tag="ACG8LA_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFQ0202585.1"
                     /translation="MKLLHLQYFKKVFETKNVTQAAKELFISQPALSRAIKHLENELG
                     VPLFYHSGRNIETTVYAEEFYPYAVKTLDTLEEGIKLLSSVNEKIVTSVILYLEVASV
                     SIPNLVRIFMEKHPDIQLTIMQHHLPDDITDPVLYITSEMKPGMTNIPIMKEPVYVAI
                     PKKHPLAKKEHLQLEDIQRTPILMLSKSNAFRHTLDAALEAKSIELTISSTTDDPATL
                     RSIVKQGLAVSFFPKVSWSYDKNDPFVLREIKDLPLTRTIYLSSSFTEDHPLIKMIAK
                     TMREFYLGK"
     gene            complement(58252..58614)
                     /locus_tag="ACG8LA_000249"
     CDS             complement(58252..58614)
                     /locus_tag="ACG8LA_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HFQ0202586.1"
                     /translation="MLTKKELIDHINETYNLSPEYIFKKFPDYCVFRHQKSKKWFGVL
                     MSVPEEKIYDDASDHRIINILDLKVDPELGGILRGKEGYFPAYHMNKEHWISIDLRKI
                     EKLDELADLIDGSFKSTQ"
     gene            complement(58803..58985)
                     /locus_tag="ACG8LA_000250"
     CDS             complement(58803..58985)
                     /locus_tag="ACG8LA_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202587.1"
                     /translation="MIFFISEYINQTPFYSKNTEKINGGQVSTDFSIIVYFSGAFTDD
                     KNFIMNLKNDTTKIKK"
     gene            58960..60399
                     /locus_tag="ACG8LA_000251"
     CDS             58960..60399
                     /locus_tag="ACG8LA_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0202588.1"
                     /translation="MYSLMKKIITEKDIRRHVSLVEQLLNHTKITVNELAEIIGTTER
                     TIFSDLQSIRSQLPEGWDIISDQAGISLQNQQNLLTNDLWEIFFKQSVSVELLKNLLF
                     TKKVAVPDFLADHGLSYGTLKRHVTKINQRLASYDLQIDLTKYTACILGKERAIRTFY
                     HRLLIPFTHNNYFFEDYSIHESHYFQFLRNLSQTELAVETEEIFGTCWFFINTIRIKA
                     NCRLDSSIHTNSTLSSLYDSALKKLYLTEGIYLKDTELSFASFCFLESWNYNNNYGQE
                     TARCLHHSPFLEVLETFVEELASELSLDQLKKTSLTDNLALLILKYHESPILIEALDR
                     QYHRFLETYDQQYAHLYQQKENLLNDLKKEIEINEPNYFLQLLSLLIQQTIFSIKPNL
                     FNVYFIFQGEPSWKAFLQQELKDYLGKRVCFLPIELTDLSTISFEKTDILISNFPLDS
                     LDIPIVYISSIPTKNELNRLTELTFKTFL"
     gene            complement(60406..62958)
                     /locus_tag="ACG8LA_000252"
     CDS             complement(60406..62958)
                     /locus_tag="ACG8LA_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HFQ0202589.1"
                     /translation="MNWYRLTVEDVLKNYQTSTEGLSQEERQKRLTDQGYNEIKARQQ
                     TKRWKKIAKHFTDLLMIVLIIASFLKFASSEYIEGSIILFVVIVNGLVSYWQERKAEE
                     SLNGLKQLMGQEAIVLSNGMQEKIPAKELVKGDVIVLRAGDVVPADIRLIEAHDLLVE
                     ESILTGESEASEKSHAVLTEEESIGDQKNMGFSGTLVQSGSAVGVVVETGNTTEIGKI
                     NQALQSVEQQTTPLIKKINRLNKQIFQGILCLSLFLVIFTTFRYGMDWHILLSATIAL
                     VVSMVPEGLPAVLTMILSVGVHEMAKEKAIIKGLPSVETLGSMTVICSDKTGTLTKNE
                     MTVVDVAAKEEACVLSIMKNCQELKTKEEQKTENLSGNPTEVALIRHTETANLPLKKI
                     EAKIPFSSEYKYMATMHAEEKGAVIYVKGAPEVLFAKSTLSSAEQEAWSQTAAEFARK
                     GQRVLGFAYKKVDSKQELTHETLTQLTFAGIAGLIDPPKESAVKAVKECQQAGISVKM
                     ITGDHKDTAKAIAEQIGLKHTAKVLEGIDLDLMSDEELIQQVPIVDVFARTTPEHKLR
                     IVKALQKNGEIVGMTGDGVNDAPALKRSDVGIAMGIKGSEVSKQAADMVLGDDNFHTI
                     AKAVKEGRRILDNLQKTINFFLPTALAQGLILIWALMLNRPLPLSPVQILWVNMVTTI
                     TLSYALGFESPDPEIMKRPPRDPKQGILSGYHLFRIIYVSLLIMVPAYLLAMQFEGQS
                     LQQTILLQNIVLAQAVYMINCRELSKPSLNQGLLQNKALFLSLGILALLQGMVIFLPV
                     GQQLIGTVSLTMTQQLLIGANVILLFLVVEIEKGIMNKLFRKKEKTAREYSR"
     gene            complement(63072..64403)
                     /locus_tag="ACG8LA_000253"
     CDS             complement(63072..64403)
                     /locus_tag="ACG8LA_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015171 - amino acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFQ0202590.1"
                     /translation="MEKPAMKRTLTNRNIQLIALGGAIGTGLFLGSAKAIASAGPAVI
                     LVYLICGLAIYGLMRAMGDLFLANSTFNSISDFVDYYLGKKWAFFVNWTYWLCWLGAG
                     LAELTAIGLYIHFWFVHVPALISGGSALMILMAVNLVAVKWFGELESFFSIIKILGIF
                     LFILLGIGLSVSDFHTQSIGIKENFGQIDELLPFGFAGMVVSFPMVLFSFAGIEMIGL
                     TVGETSDPQKNLKKAINCLPWRILFFYIGTILSILFVVPWHCLDLKESPLVTMLQVIH
                     CQGGAAIVNLMILVASLSSANSAVYSTSRILYQTAKEKSLPHWFCALSKKGVPLHGIL
                     ITGMLFFAGLCLHFFVADSRLFFQLLAGMTTSCFLFVWSSILCAHVQFIKEKKRNTTQ
                     RYKDLALLVFFTSIAFSLLFESTTRFIPFLLVIWFVFLNFVYKRISNRNIS"
     gene            complement(64369..65847)
                     /locus_tag="ACG8LA_000254"
     CDS             complement(64369..65847)
                     /locus_tag="ACG8LA_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFQ0202591.1"
                     /translation="MKDTGSSKQITTMTFIGMTCALVASVRNIPDVAATSWTMIFYML
                     VAVLLYAFPISLISGEFAGMFPQKGGPELWVSNALGKKWGFVVSWLLWVQMFPGMVMV
                     ASALAPLFGNIIDNVPLGLNSKFTLVVILVVYWIITFLNLKFDMAKIGGKVGVWLGLY
                     VPLTMMLLLGFAAWIKVGIVPTGTLGSFSWDKLIPDTTTASSFVYFAPIMFIFTGIEM
                     SSVYITRLENPVKTYIRGVFAALIFIFFVNILNALVVANVVPKGQMELNNIAQSISIY
                     CQILGLPHLIVNLFSLLVFIGVAVQLSAWASGPAKTVTESARKGAYPPKFNFWKTNQF
                     DVSKSVILTQSVIISIFALFYLLIPGVNQAFLMLVNSTTVIYCIVYVIMGIAVLRLRY
                     THAKLNRPFRIGKKEKKSNLGVWTVVIVLFAAIGFSVGLTMKAGTWINLIAVTAISVI
                     LFVVPLCIEKIKKPSWEQEVAMLLEKEKGELDGKTGNETDSN"
     gene            complement(66152..67987)
                     /gene="tdc"
                     /locus_tag="ACG8LA_000255"
     CDS             complement(66152..67987)
                     /gene="tdc"
                     /locus_tag="ACG8LA_000255"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004837 - tyrosine decarboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006572 - tyrosine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HFQ0202592.1"
                     /translation="MKDMDIKAVFIGDKAENGPVYKMLLNKMVDEHLGWRENYIPSDM
                     PAISEGDKLTPDYLATRDHMIEVLDEVSQRLRAGSIPWHSAGRYWGQMNAETLMPALL
                     AYNYAMLWNPNNVALESSMATSQMEAEVGQDFASLFNMTDGWGHIAADGSIANLEGLW
                     YARCIKSIPLAVKEVLPEKVKKMSEWELLNLSVEEILEMTESFTDEEMDEVKAASSRS
                     GKNIQRLGKWLVPQTKHYSWMKALDICGVGLDQMVAIPVQEDYRMDINALEKTIRELA
                     GQKIPILGVVAVVGTTEEGQVDSVDKIVQLRERLKDEGIYFYLHVDAAYGGYARSLFL
                     NEAGEFVPYASLAEFFEEHHVFHHCVTIDKEVYEGFRAISEADSVTIDPHKMGYVPYA
                     AGGIVIKHKNMRNIISYFAPYVFEKSVKAPDMLGAYILEGSKAGATAAAVWTAHRVLP
                     LNVTGYGQLIGASIEAAQRFREFLDHLTFTVKGKTIEVYPLNHPDFNMVNWVFKEQGC
                     TDLNAINELNEKMFDRSSYMDGDVYGERFITSHTTFTQEDYGDSPIRFVERMGLTKEE
                     WKKEQKITLLRAAIMTPYLNDDRIFNFYTKKIAKAMEKKLNEIIQ"
     gene            68457..69884
                     /locus_tag="ACG8LA_000256"
     CDS             68457..69884
                     /locus_tag="ACG8LA_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0202593.1"
                     /translation="MIEEYIEKNILRQLFLCGQFYVNKEVNLEKLSNLLHVCKTTLLN
                     DINNIKKEFEEQIAYTHREKDRYTLYFSEHIPRCKIMQQLSQNSLFLKTCLLYLEEDE
                     PDYLQLTECEFISVSKAYSLKKQVLAYFNDCGIEIDRYSPRFTEMERRLLLLNVSYRL
                     GGFNSWELPESFFERADRFIESVTENSGRFYDKENKEILSIGFAISFLRQQVCAVTID
                     SKFIEEIKKRPIYNYVESAWENTDFQTYYKKEEFAFILTLFNLCNYGFHSYQLIAEDF
                     QQLHQVFIDNTPEIKELVATFESHFNQELFGNQPFERALIHLMRSAWDNYQLFMPEKF
                     YLLNEEQTNLYKEVQTIFSSWSSQLPYDLRLNPNCMRAFVIELSGILRLTKEHLTIYI
                     VTNSDVHYLIYREALEAVTTFDFQVAPTIYSSISDIKKYAQQSSNRVLCERTLYTPDA
                     VQYENIIPISINTIDRAIISAVQNK"
     gene            complement(69976..70341)
                     /locus_tag="ACG8LA_000257"
     CDS             complement(69976..70341)
                     /locus_tag="ACG8LA_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HFQ0202594.1"
                     /translation="MTTELMQFLLPYFEKLVLGLDIFAICLLVWGVCLSIKDFLKYLF
                     VHTKVQSDRVSENNAIKKMLGGYILLSLEILVSAGIIESIIKPTLQDIFQLAALVVIR
                     TIISYFLNKEIGPVDVQNK"
     gene            complement(70338..70703)
                     /locus_tag="ACG8LA_000258"
     CDS             complement(70338..70703)
                     /locus_tag="ACG8LA_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HFQ0202595.1"
                     /translation="MFRSNLIEFLEWIIAILNICSIGILIVGIVLVLFKLFDWSHVKK
                     NYAERNTRNADTRKLLASYILLSLEVLVVADIIESVIKPTWTDILKLALIIIIRTVIS
                     YFLNQEIEDKEKQRRGEVG"
     gene            complement(70895..71143)
                     /locus_tag="ACG8LA_000259"
     CDS             complement(70895..71143)
                     /locus_tag="ACG8LA_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202596.1"
                     /translation="MKNASLFSLSISKDSSFLLECQMIGREEKGNFDKKEEVSDFPVN
                     KNRVGKKKRFEEVYGSIFRNLGTKKAPRQCFFEKLMTD"
     gene            71142..71270
                     /locus_tag="ACG8LA_000260"
     CDS             71142..71270
                     /locus_tag="ACG8LA_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methanol dehydrogenase"
                     /protein_id="HFQ0202597.1"
                     /translation="MSKKLIKVGIGLGLLALGAAYLGKKTGLFEDDSHLYDEFESI"
     gene            71327..73021
                     /locus_tag="ACG8LA_000261"
     CDS             71327..73021
                     /locus_tag="ACG8LA_000261"
                     /EC_number="4.2.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050151 - oleate hydratase activity
                     [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA];
                     GO_process: GO:0006631 - fatty acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oleate hydratase"
                     /protein_id="HFQ0202598.1"
                     /translation="MRKSKAIMIGAGIANMAAAVYLIQEGKWKGDQITFYSLDDHGSN
                     DGAPTDTVVDEYWNKNHPLENQKGYIARGGRMLNYRTYVDLMDLLSRIPSVTEPGMTA
                     EEDTRDFDAKHRTFDKARLMEGGKGIIDGGKLGFNNKDRILLTKLIAMPDSEEEKLDN
                     ITIEEYFKDDPHFFETNFWFMWETTFAFRTRSSAQELRRYMHQMIYEFTQIEHLVGVN
                     RTRYNQYESIMLPLIEYLKEQGCKIILNRRVTDWEFKETPMQDEITVTGLKITNTLTQ
                     EEEYVVVDEDTAVIFTNGSITDSATLGDYETPAVENMDYGAASSLWKKASERFYNLGN
                     PDKFFADRDASEWVSFTLTTKNHLLLNEITRITTQEPGNALNSFISTTPITPLGQKDV
                     NMSIVVHHQPHFTSQKPNETVIWGYFLYPRRRGEFVDKQYIKMNGKEMLEELIGQLSK
                     VDPGPVNIREKETEIFDSVINNIPVYMPYASALFNNRAKSDRPKVIPKHSTNLAFTGE
                     FVEQPYQMIFTEQSAVRSGEIAAFHFAGIPMSRLVKTPRYDKDIPTLARAAKKMFE"
     gene            73121..73417
                     /locus_tag="ACG8LA_000262"
     CDS             73121..73417
                     /locus_tag="ACG8LA_000262"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202599.1"
                     /translation="MQAFEHRLPRGCEKAALHQVIRTPKLKLLLMFLTWLDLLPQMQA
                     FEHHLPRGYEKAALHQVIRAAKLKQLLMFLTWLDLLPQMQAFEHRLPRGYEKGV"
     gene            73795..74928
                     /locus_tag="ACG8LA_000263"
     CDS             73795..74928
                     /locus_tag="ACG8LA_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HFQ0202600.1"
                     /translation="MKAVTWQGKQKMEIRNVDDPKILEPTDAIIRITATAICGSDLHL
                     YHHGEAVLEKGYVVGHEPMGIVEEVGSQVQTLKKGQRVVIPFNISCGHCHFCLNHMES
                     QCDESNPDQLYGGLFGFGKLNGNHWGGQAEYLRVPYADSTSFVVPDNDLPDEKVLFLS
                     DILPTAYWSVENAGVKKGDTVVILGSGPVGLFAQKFAVMAGAERVIAVDPVQHRLDKA
                     ANYNGVETYFLEDTAQAGTELYELAKGGADVIIDCVGMDGLEPVKEKAKNLVSLQSGT
                     ISPLQMASQAVKKFGTVQVTGVYMTPASSYPLQEFFMRDIAVKHGQAPIIHLMPKIYA
                     MIAEGLFDPTQIITHSLPLSEAAQAYEIFDKKEDKNIKVVLKP"
     gene            74959..75279
                     /locus_tag="ACG8LA_000264"
     CDS             74959..75279
                     /locus_tag="ACG8LA_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YrhK family protein"
                     /protein_id="HFQ0202601.1"
                     /translation="MPKIKRNTHEIEIGKEEDIEIRGRRFRFYFQNRYTLISLAVDLL
                     TGIFYIFGSLASLTKIPDRYGTYFYLAGAIFLTIRPILRIVRNIFIYDEKKAMKRTSK
                     KKEA"
     gene            complement(75308..75772)
                     /locus_tag="ACG8LA_000265"
     CDS             complement(75308..75772)
                     /locus_tag="ACG8LA_000265"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFQ0202602.1"
                     /translation="MVTYNWIKLREHPELVKQSANWFSSKWGVPAVVYEESIRTGIAN
                     KESIPQWYVVLDEKETIVGGAGVIENDFHNRPDLTPNLCALFVEPEKRKQGIAKRILA
                     EIRKEMHQLGYEKLYLITDHTTFYERYEWTFLTMVKEESGTTARLYQSDTIG"
     gene            complement(75903..77156)
                     /locus_tag="ACG8LA_000266"
     CDS             complement(75903..77156)
                     /locus_tag="ACG8LA_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HFQ0202603.1"
                     /translation="MDKFVAFMEKHFIPVASKIGAQRHLVAIRDSFMVSMPLMILGAL
                     AVMINNLPIPGFQELMNSIFGGESWKGFGAAAWNGTFAILSVLIAFLLAYHLANGYRK
                     DGVSAGVISLGSFFALGGALGMSSNGLFIAIIVGIISTEIFVRLSGNEKLIIKMPDGV
                     PPAVAKAFASLLPAMITISAFALVAAIFAAFGVDDIVGSFYTVVQEPFMGLANSYPSA
                     LLLAFITPFLWFFGLHGANMVDPLMQTINAPAIEANVNAIAAGHSAPFIVNKPFFDSF
                     VNLGGTGATLGLLLAIYLVGRKNKPYMVVTNLSIAPGVFNINEPTMFGLPIVLNPIMF
                     IPFILTPMVLVSVAYFATSTGLVPAATVMPPWVTPPIIGGVLATKSIAGGVLAAVNLV
                     LSILIYLPFVKVATIQERRKEALDA"
     gene            complement(77185..77502)
                     /locus_tag="ACG8LA_000267"
     CDS             complement(77185..77502)
                     /locus_tag="ACG8LA_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HFQ0202604.1"
                     /translation="MEDQKNLEAIMGLIMFGGNAKSDAMEAIAAAKKGDFTLADEKIK
                     DAEESLVQAHHSQTEMLTQEAQGNHVEVTLLTVHSQDHLMTSIAFTDLAKEIIDLYRR
                     LNA"
     gene            complement(77528..77848)
                     /locus_tag="ACG8LA_000268"
     CDS             complement(77528..77848)
                     /locus_tag="ACG8LA_000268"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFQ0202605.1"
                     /translation="MEKKTIMLVCSAGMSTSLLVTKMQKAAEAKGMEADIFAVSASDA
                     DNQLESKNVDVLLLGPQVRFMQNQFAEKLAPKGIPLDVINMADYGMMNGEKVLDQAEK
                     LINK"
     gene            complement(78312..79727)
                     /locus_tag="ACG8LA_000269"
     CDS             complement(78312..79727)
                     /locus_tag="ACG8LA_000269"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFQ0202606.1"
                     /translation="MKITIPKNFILGAASSAWQTEGWKGKKEGQDSFIDSWYKNEHFV
                     WHNGYGPAVATNFMEQYQQDVDLMKSIHLTHYRTSINWARFFTDYENCIVDEEYAQHI
                     SEMIDSLIEADVEPMICLEHYEVPAFLLEKYDGWSSRKVVDFYAKYAQIAFDRYGDRV
                     KNWFTFNEPIVPQTRCYLDAVRWPHEQNTKKWMMWNYHKVLATAKAVEIYRSGNYGGR
                     IGCILNPEMVYARSNSPEDQKAAYMYDLFYNRVFFDPMVKGYYTEEFLELCQKQSIYF
                     DPATEDLETIQHHTVDFLGINQYYPKRVRAPRYQWNEETPFHPERYYEVFDLPGKKMN
                     NSRGWEIYPKIMYDIAMYLKENYHNIPWLITENGMGREYEEQYMDEKGIVQDDYRIEF
                     IGQHLHYLIKATEEGANCEGYMLWAFTDCVSPMNAFKNRYGLVRIELNDERSRTLKKS
                     ASWYQTLIDKRELDLPDEIYK"
     gene            complement(79744..81060)
                     /locus_tag="ACG8LA_000270"
     CDS             complement(79744..81060)
                     /locus_tag="ACG8LA_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFQ0202607.1"
                     /translation="MRGSGMSFMDKLANVLGNVATRINNLRYIMVIKNAFAALIPVII
                     TGAFGTLFSAMVFDSENGLAQISFLRFLEELKPIASAISYVTLSFLTIYAVFLIGIEL
                     AKLNKVDGVFPGIIAVMSYLSVNPTVYELVNENQTVIVENVLAKQYTDTKGLFLGMLV
                     SILSIELYCWLRKQKKLQLRMPDTVPTNVSASFSALFPTILTVSGIAAAGFIIKELTG
                     MYLYDIIYNVVQRPLEGVVQGLPGILLLMFIAQVFWVIGIHGNQMVKPIREPLLLAAI
                     AVNTEAFEAGKEVPNIITMPFWDMYMSMGGSGVTIGLLIAVLLVGKREDMKQITKLSL
                     APGIFNINEPVIFGMPIMLNPILAIPFILTPLITGTIGYFATALGFAAKAVVMVPWPM
                     PPIVNAYLATAGNIGAVITQLVCIIVSILIYLPFVKVANRVENDGI"
     gene            complement(81210..81908)
                     /locus_tag="ACG8LA_000271"
     CDS             complement(81210..81908)
                     /locus_tag="ACG8LA_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FadR/GntR family transcriptional regulator"
                     /protein_id="HFQ0202608.1"
                     /translation="MEENKTLVEVTTDKILRYLKEMQLQVGDKLPNEYELSDYLEVGR
                     STVREAVRALASRNILEVRQGAGTFVSDKRGIANDPLGFSLIEDQDRMIRDLFELRYL
                     LEPKMAGLAAEYATKNQIVQMKKLTQKIETSFREGTQEHVQLDIDFHTMIAEASGNVA
                     LLHIIPIINESIALFNKNYDIQHLKIETIDIHTEIVQAIERRNALAAFDAMTVHMAIN
                     RRELQKIIGEKETN"
BASE COUNT        23802 a        17361 c        14039 g        26854 t
ORIGIN      
        1 atttttagaa aaaggagtgg ggtttttatg gcagaaatcg tcaaagtcac acatttgaaa
       61 aagagctttg gtcgtttcga agctttaaaa gatgtctctt tcaccgtaca ttcaggtgaa
      121 gtcgttggat ttatcggacc aaatggttct ggaaaatcca cgacgattcg gacactttta
      181 gggattataa aaaaagacgg cggaacggca acgatttttg ggcaagatgt atgggaagat
      241 agtttatcta tccatgaacg tctttcttat gttccaggcg atatctcttt gtggggaaat
      301 ttgactggag gagcgatcat cgatctcttc atgaagcttc atggaaaagg gagtgctcaa
      361 aaaaaagatg aactgattca acgtttctct cttgatccta agaaaaaagc aaaaaactat
      421 tcaaaaggaa atcgccaaaa agtgggcttg attgctgctt tggctgttga ttcggatctc
      481 tatttatttg atgagcctac ttctggttta gatcctttga tggaaacgat tttccaagaa
      541 gaagttgaaa aattgaaaga acagggcaaa tccatcctac tttcttctca tattctcagt
      601 gaagtcgagc gactagcgga taaagtcgtg atcatacgcg aaggaacact cgatgaagaa
      661 ggaacactcg atgaattgcg tcatttgact cgttcgacca tcactataga aacagaagca
      721 gagaatagtc acttagcaca attgaacggt gtccatgact ttgtgcaaaa aggtcacctc
      781 gctcaatttg ctgctgataa cgaagctttc gatgtgattt tagctgaagc gtccaaatta
      841 ggtgtgaaaa aatttgaatc tattccaccg actcttgagg atttattcat gagacattat
      901 gaaggatgag gaggaagcga aatgactgat aaattttcac gctggtccac ccttttttct
      961 caaaacctta gccgtgactg gaaaaagatc ctgatatggc tagtcggtgt cactgctttt
     1021 tctggtggtt ttgtccctgc gtttgaagaa ttgacttccg gacaaggatt agctggatta
     1081 tacgaaacct tgcaaaaccc ggcaatgatt gcaatggtcg gaccaactcc agcttcgaat
     1141 gctgctgagt atactttagg agcgatgtat gcaaatgaaa tgttgctttt ttgcagtttg
     1201 tttgctgctg tgatctctgt tttacacgtg gtgagccaaa cgagaaaaaa agaagaactt
     1261 ggtctgattg aacttattcg ttcctttcga gtcggacgtc aagcaaactc tttagctgtc
     1321 atcgctgaaa gtattctgat caatttgctt ttagcaatat cgatcagctg tacgatgatt
     1381 tttttccaag cggattcgat cactgcagaa ggtgcttggc tttttgggct atctgtaggt
     1441 agtatgggga ttttggggag tgccgttgca ctgtttgctg cacaactgat gccaagttca
     1501 gccagttcga atggtctgtc tttagcgttt ttaggtggac tttaccttct acgagcaata
     1561 acagatgtag ctgattcctc cctttcgatg tggaatcctt taggctggtc ttatttgacc
     1621 tatccattta caactaacaa ctggattcct ttgctttatt tgtttttgtt cagtctaatc
     1681 ttgataatca gttcatttgt tttagaggaa catcgagatt tgaacaccgg ctatatcccc
     1741 gaacgtgaag gaaaaccgta tgctaaacgt tctcttttat ccttgcgtgg tttattattc
     1801 tatctaaata aagggatgac aatcagttgg cttatcactt ttggtttgat gggggcggca
     1861 tacggctcta tctacgggaa tatgcaacag tttttagaaa gtaacgactt aatgaaacag
     1921 atgtttatcc aatctggcgt ctcaattgaa aaaaacttta caagcacgat catggtagtc
     1981 ttgatttgtc tagctgctat tttaccaatt gctagcatca atcgtttatt tacagaagaa
     2041 acccacggac gtatgaatca gctgttcgca acaaaaattt ctaggaacca actttattgg
     2101 accaatatgt tactagctat tctatttgct atattggcaa tcctgattag ttctggtgca
     2161 ctagggcttt ctgctttggc ttcgatgaag gatgcgaaag acatggatct attgatgttt
     2221 cttaaagccg ggttcaattt cctgcctgcc gttttagtgt ttatcggaat tagtggcttt
     2281 ctattcggat ggcttcctcg aatcggtaaa cttgcttata tctacttagc ttactccttt
     2341 gcactcaatt actttggcgg aattttggat ttaccagaat ggttttccaa aacagctgtc
     2401 cctagctggg ttccacggat gccaaacgat tcttttgatc tttccgtgtt ccttacgtta
     2461 tcatgtatca gccttgcact gttcgtcctt ggttctattg gttataggcg aagagactta
     2521 ctagaaggat aataaaaaag catgtacaat ttcatgctag cctccaaatc tgggtcaaaa
     2581 atccaacatt tggaggtcat ttttttattt acaagtcttc taactgctct ttatcaatga
     2641 tccagacttc tcgattcttt ctttttacat aaccattctc ctctaataat ttaaattttc
     2701 tagataaagt ttcgggggtc gtaccgataa atgcagcaag ttctttcatt ttcattggca
     2761 ggaaaaagtg atccttccct gtcgctttag ctaagtcaag cagatagaca gcgactcgtt
     2821 cttctacttt ttccatcatc aaaaaagttg tctgctgctg tacttttgtt aatttctcaa
     2881 cgttgattgc taaaagtttc agactaaggg cgggataatg cagtaagagt tccgagaaat
     2941 ctttttgtct caatatgcaa atttccgttt tttctagtgc ttcgccaaat aaagactcat
     3001 ttggaacgcc tagcaactgg ctctctccct catatccgcc cggctctatt actcgtaaaa
     3061 gctgttcctt tccgctagca gataattgat acactttcat actgccggag gccacgatca
     3121 ctaattgagg ttctccattc ggcgcaagaa tctgttctcc tttttccaca tagtgatgtt
     3181 tgacaagtgc gtgtactttt tcttgatctt gctgtactaa gtgattgaac aaaggaacaa
     3241 atgaaacaca taaatgatca tgactcataa tctctcctcc ttctaaacag ctatttctaa
     3301 taaagaaaca taacttccct tattccaact gataattttc ttttatcata gcataaacgt
     3361 caagcgaacc agataccagc aaatagagtg gatttctttt tgtcccttgc tttattttcc
     3421 ttcttttgag accttaagta attgattcct atcaattttt taaatattta ctttttgaat
     3481 aatcaaaaac aaaccttcac tcgcaagccg agagtaaggt ttgtttttcg cattgcttat
     3541 ttcgtgttgt ctattgaaat ttttccgcac ctagcttttg atatagtggt gctagttctt
     3601 gtaaggtttc agcggttatt tgctcaacgt gttcgatttc ttgcggatag aagaatagtt
     3661 tacccatttg aaaggttcgg tctctcatcg cttttttcaa ctcttcttgt ttctttgtat
     3721 cggacaaata gtcagacaaa gctaagtggt cgtcaagttc atgttctggt tgcggccata
     3781 tgtaataatc cttgatatcg actgttttgc tccactcttt cagtatcgca agcaactggt
     3841 tatacgctgc aatgctacca tatcgttctt cgcttttata atgttggtac atcaaataga
     3901 tttggtattg tttttgattc aacaaaactg ctagacaggc attctcgtct tgacgagatt
     3961 cgcttcggta cgcgctccaa aaatgactgc gtaaattcca gccattcgtc cagctttcga
     4021 ttttaggttt gctcatgccg tacatatcag gcaaaagtgc agctgtctgg agctgaatct
     4081 ctttccattt ttgccagtgt tctttatatt ctttcttgat ttgttcaatc ttatctgttg
     4141 gatggctctc tttgagctgt ttgaatgcgt agattggtcg atcaaacaac tgataatctg
     4201 attttccaag ttccattgtt tcgcctcttt ccgttatctt ttgtattcta cctgaatttt
     4261 gcgatatgga caaatagagg ttgtgaaaaa gctgttctgc atcaagtcat aagaacagcc
     4321 aaacaaaaaa ctgcgatgag catcaccgca gttttattga acttaaggtt gattgatcac
     4381 atctaaaagc gttgaaaata aaatggcact agaagcagct cctgggtcga tatgtccgat
     4441 tgcacgctct cctagatagg aagctcgtcc ttttttagct accaagactt tggtgtgttc
     4501 ttttgcctgg tcaatgattt cttttgttaa attccctgcc ttcaatgcct ctgtgactgg
     4561 cagccaaaca tctaacatcg ttttatcgtc agcttctgcc tttcctcggc tttgaatacc
     4621 cgctgttccc tgctcgatca cttcgcctaa tttttcttga gaatcaatag aatcgacctc
     4681 ttttgtcgct ttcatcatgt tcatgaatgc agatccgtat aacggaccag aagccccacc
     4741 gactttcgat atcatcgcca tagagaatac tttgaatgta tcgctgattg tttcaggatg
     4801 atcggcttga aaagcttctt cataagctga aacccctctt cccatgttat ttccatggtc
     4861 tccatcgcca atcggggtat ctagatcact gagatattgt ttgttctgat tgattgcctc
     4921 tgcaaattgc gtgagccatt cttggatttc ttgaacggtt agtttcatat tatcaccctt
     4981 ttatcttgag attttttacc atgaaatcgt ctgtacattg ctttctaaag aatctttcca
     5041 ttgtgtctcc gtcaagtcga tcagtgttag agaaagacct tgcatatcta gtgaggtcat
     5101 aaaattaccg acttttcgga aaactacatt gacgcctctt tcttccaaca gagctaaaac
     5161 atcattcatg aacacgaact gttccatcaa aggcgtcccg cccattccgt tgactagtac
     5221 acctgcttct tttggtaaat tcgagtaatc atctaaaatc ttagtaacaa gttcctttgc
     5281 cagtacttta gaaggctgca tcttttctcg acgatagcct ggctcaccgt ggataccaac
     5341 accatactcg atctcatctt ctcctagttc gaatcctggt ttccctactt ctggtacagt
     5401 tgctgctcga agcgctagac cgatcgtctt agttgcctgt acgacctttt ctcccagttc
     5461 tttcaactca gctagggaag caccgtttct tgctgcatcg cccacgattt tgtgtacaag
     5521 gacagtacct gcaactccgc gttttccagc agtatacgta ctattttcaa cggcgatatc
     5581 atcatctacg atcacacttt ctacttcaat atcgtccata gcagctaatt cctttgccat
     5641 atcgaagttc aatgcatccc ctgtataatt cttaacgatc agcaaaactc cttttccact
     5701 atcggcttcc ttaatagccg tctgaatctg atctggagtt ggagaagtaa acacatcacc
     5761 aagcaccgct gcacttaaca tcccttcccc tacaaacccg gcatgggatg gttcatgtcc
     5821 gcttcctcca ccagaaacca aaccaacttg ttccgctttc tgattcttgg ctacaacacg
     5881 ggaagattct acacgatgaa caagttctgg atagcttttt actaatcctt ccagcatttc
     5941 ttcgacaata ttgcttggat cattcatgat ttttttcaat ttattcccat cctttctttc
     6001 cggcattttg tgcttctgtt aagatttgct gagtatcatc tgttataccg gcagtgatgg
     6061 ctgctgcaaa agctccttcc actaaaggcg catccaccag atgataacgt tgctgctgct
     6121 cttcttccaa catgtctttt gccagttccg agttcaatac cgcgctaccg atatccgcaa
     6181 aaacaaaata actagctgca tcgcttgatt cattgactgc ttctacgatt ttcatcgggt
     6241 ctgatccgat ctcgccattt attccgccga gagaaaaaat ttgcacctct tcggattttt
     6301 gcatctgctc aatcatttct ttaataccat ctgttacttt ttgactatga gaaataagca
     6361 aaatactttt tttcacaaga atcttccttt cttttacata gttgctaacg attggtttcg
     6421 ctttcattaa tgaacaattc aagtatataa taaatttcta attttgggaa aatatgtgta
     6481 gtgcttcttg aagtttgtta tactttaatt aaaagagagg agtgatcgaa tgattacaac
     6541 aacaacgaac agtgtagagg gaaaagccgt agtagcttat aaagggatcg tttttggtga
     6601 ggtcattact gggatccatg catttaaaga cttggaggcg gggttgcgaa atatctttgg
     6661 cggccgctca aaaagctatg aaaacgaact aatgggtgca agagaagaag cacttgccga
     6721 aatggccgaa cgtgcaaaag cattaggagc tgatgcgatc attggcgtaa aaatggacta
     6781 tgaagtatta ggcagcgaca atggcatgct gatggtcaca tgtagtggaa cagctgtctc
     6841 cacgagataa gtaggggaca tctgttttaa taactaaaga gagatgggac atgtagtggc
     6901 actcaagaat tagatttttc agtctaactt cgaggtactc taccttccca tcctctcttt
     6961 tttatttctt tttgcggatg attccgtaag ctgctgcgac taacacaccc gcccctgcta
     7021 aggaataact gacagaagct gttttttcat ttgtttttgg caaagtctga cttgttgatt
     7081 tggatggctc tgtcgtttgc tgaactgttt ctgtcgtgct tccagaggtc actgattttt
     7141 ctcctgccga atgcaaaata tcttttattc gttggaaact agctgctaag tcagcttttt
     7201 ttgcttcaaa atcattagca actgtttgtg cttcgctgat ctttccgtgg attgcttgac
     7261 tggccgctgt gatatccgct tgagtttgac ttagctttcc agaagctgtt tgagcaacct
     7321 gatttaattg ctgattgaat tcttttgctt gttggatctt cccgtcaaga tctgtttgga
     7381 cagcttccgc ttttgctttc gcttcggcaa gctttttctc aagttgtgca cggtcatttc
     7441 ccactttatt tttaagatca gctaaatctt gatcgattgc tgcttggtct tctttcaatt
     7501 tgttttttgc agcttctaat gcttcttcga gttcttttct tttattttcc aagtcttgca
     7561 aatgatcgat ttggtcagaa gaggtagaac tatttattga tgtatcttct gaagatgaaa
     7621 tcgtttctcc tgaattatct gtcggtacat tggaagtcat ttctgtttcc gaggcaccgt
     7681 tttcagcacc agaagagctt atggttgttg aaggttctgt ttgagcaggt tcagaagttt
     7741 ccgcaaaagc tgtctgtccc aataagaaaa tactggaaac agcaattggc cagattaacg
     7801 gcttcattct ttttttcatc acttttccca tccttactac tttttaacta atttcttatt
     7861 ataagcaaaa atgtttggaa gaaccataaa cacaacaggc tgtttgtcta aaaaacggtg
     7921 catcttttat ttttttgtac gttccgggct tttccatgtc ccgcttccat aacctaaaat
     7981 cgttttgact gctggaatga aagtcgtcac gatcgttatc gcgttcacta tccagaacaa
     8041 aagcatatat agtggtgcga aaagaaggta tttcaatttt cttcgtcgat catctacaat
     8101 cagcgaagct agcaactgga aaaatcctgc gaccatttca aagcagatga acacaaaact
     8161 gaatgtaaaa gtaatataaa tctgttcgta gtttccttga tatacataat gcccgattaa
     8221 tccagcaaaa agaactacgg aaatacaaaa gaatattgac cagacaatac tcaatgtttg
     8281 atcaatgaag atgatcgttc ttccaatatg tttaaaagga tggagcatca cttttttgaa
     8341 attcgtcagc cagacttctg ttccaccttt tgcccaacgt tttctgtgtc gatatagcat
     8401 cttcaacgtc acaggtactt ccatgaaaaa gataatctca ggagcaaaaa cagataacca
     8461 gtcatttaac tgatgatccc aagcaatact gatgtcttct gtcgctcgat cttgtctgaa
     8521 tccgcccaca tcgatcaagg cttcttttcg atacatcgta tttgctccac tgtacgcata
     8581 aagaccaccg aaaacagctg actgtgttcg tttaatgatg cccacgatac ttgagaattc
     8641 aaccgtttga gattttgcaa tcaatttggt acgattttgg acatccatat ttgcagtgac
     8701 cgcagcaata tgtcttgcac cagggcgaat gaaataattc acatacctaa tcagtgcatc
     8761 tggctccggt accgtgtctg catcattgct taaaatcaat ttcccttttg caaaggcaag
     8821 tccgatatta aacgcgtggg cttttccttt atttttttcg atccgaacca cacgaagatt
     8881 agcgtatttt ttcatcagtc tagctaatat ttctggtgtt tggtccgttg aaccatcgtc
     8941 tgtcactaat acctcatagt tgtgataatt caatttcgtc atcaaatact cgattgtata
     9001 ttcgatcaca atttcttcat tatgggctgg caccatgatc gtgatgaacg gttcgacact
     9061 caagggaaca tctacccatt ctttttgctt atgtttgtat aaaaacacat aacaccagac
     9121 accaataaac catacaaatc cgcctaaaat cggataagaa acgagaaaaa aatacataat
     9181 agacaaacaa gtatctaaga ataaattacc tgtatgggtg attgagatca tttcagttcc
     9241 accccatttt ctttatacaa atctgcaatg aatgtcgtat ctagattttt ctcttcggag
     9301 acagaataaa aacggaccgt ttctctctct tcttttgttc caaaacgttc cgtatacact
     9361 tcttcaagta attcttgtct ttttttcaat ttttcatctt catattcaaa agatttattt
     9421 acttttttgt atagatttcg attgttccac ctagtcaata caaatgaggt aatcaggaaa
     9481 ctgaaaaaaa tcaatacaaa aaagccgatt aagaaataca gcattttctt ttctgataaa
     9541 aaagcgtaca aggaaaaatc cttggctctt tctggtctcg ttaatgggaa aaagacccat
     9601 ataaaaggaa gaacaacgat catccatcct aaaagagcca ctaacgtttg ccaaatcttt
     9661 aaccagtaat taccttttga aaaatactta tctttcacca aaattgatgc aacttcttct
     9721 cttgttactt ttttcatatc ctcacctcac gtttttttgt tacgacgtag gagtttacca
     9781 tacatttcat ttcttttcac ataaagtgtt cctaaatttt tcctaagaaa aagaacaaaa
     9841 catttctcat cagcaaatga aaaatatttt gttcttttta tcagttgttc tttttatttt
     9901 ttatctctta attatgttgc tctttccaat acgacaatgc ttttcattcc tctagatatc
     9961 gccgtgtaca tttgtctgcg tcttctttgc tcatctccat cgttttcaaa tggatataag
    10021 attacatgat caaattccag tccttttgct agactcaaag gaatgatttg gcagttttct
    10081 aatccatatg aatttttttt aatcgattct tgtagcgttt gggtttcctc ttctgtttgg
    10141 gtgataactg ccgctttttc tccttttaga gaaaccaaaa tctcagctag tattttcaac
    10201 aattcttcag aggatcgaaa agagcggtat tcgggttctt ttccttgcgg tcggatcgat
    10261 acgatgtcga tcttctcttg atccacagca taggttttga aaagctctgt gattgctccg
    10321 ctagaacggt aactatttct aagatcatac cgatggatcg gcagatggta gtcgtcgaaa
    10381 caacgcataa tatcagcaaa agtagtggaa gaattaaaga ttgcctgatt ctcgtcacct
    10441 actaaagtaa agtgagtttt tggaaataat tcgatcaata gacctaattg tgccagggta
    10501 taatcttgta cttcatcaat caatagatag cgaaatgctg gtacatttac cttttcaaca
    10561 agtaaatgac gaatagctaa tataatgact gcttcatcaa cagtacgtgt gggttgccaa
    10621 gcataagctg agccatatcg tttttcataa attctttcaa acaactgatg ctcatccacc
    10681 catgccattt cttcgatttg tctggttatt tttcgatatt ttttttgtaa aagtttcctt
    10741 gcataagcta caatactttg ttccgaatca tcagaaatca atttaccgaa taattccaac
    10801 tgcctatctt ctgtcaacga gagtacctga ttctgcacag caggactttt tgcttgtttc
    10861 aaaagatgat tcttccattc gctcatcagt gcctttttcg ttgcttgaag cctatcgatc
    10921 aatttaggat gagcaggaac tttctcatat attttttcga tcgttttttt agaaaggact
    10981 gtttttccat ttttagtaag tccacggata aaattcggat gatctaaaaa caaaggatct
    11041 gattgtttta gattatcgat aaactttttg ctacgcaaac gttctgtctg ctccgataca
    11101 ttttctcccg tgatacgttt gaaataagcc tcttcacctt ctatttcctc tgctgaaagc
    11161 tgtgaaacca gctgtatgat ggttagattc agtggatttc tttcacctaa tgatggtagg
    11221 acattcgaaa tatagtcgat aaaccgatga ttaggtgata gaatcagcaa gtcatcggat
    11281 gtcatcgtat ctcgatataa atagagcaga tacgcaatac gctgcatgat agcagaggtt
    11341 ttaccacttc ctgctacgcc atttaccaag atattttgac ttttcacatc ccgaatgatt
    11401 gtgttttgtt ccgattggat cgtagcagtg atagccttca tttcattggt ctcatcttgg
    11461 cctaagactt ctaataatac gtcatcttga atagctacag acgtatcaaa aaacttgacc
    11521 aaacgatctc tttccaaaag aaattgtcgt ctttctttaa taaccgtatc gattttattt
    11581 tgacgaaccg tataagaaga tggaccaatc atgttattgt aaaaaagttc ggcaattggt
    11641 gaacgccaat cataaacaag attttcatct gcatcatctg tgaaatttgc tgtaccgata
    11701 taaaaggatt cttttggctc attatccaga aagtctacaa cgacttttcc aaagtaggga
    11761 cttttcaata aacgttcgat ctttgctagc tgattttctg cgtttttctg tttgatattc
    11821 atctgatcga tttctctatt tttcatttca atcatcgaaa aagtatccag gttatctaag
    11881 taactgtcaa aattcaatcg aagctcgcca gccatttctt tcaacgactg gtttccttct
    11941 atttttgccg tatccatcga ttcccgcagt tcgttttttt tatcaattag cttttgatac
    12001 acgttcttca gatatgcttc ttctaactgt ttttgtgtgt tgaccataca cattctcctc
    12061 tttttttaaa gtggtggaac cgattagttt acctctttta agagtcgaat gcaagctttt
    12121 taacgagtat catttgttag gatatatcag ttcttcaggt cggacagttt gatataaaga
    12181 aaatgcacca tcaaggtttt ttacgtggta gccagactgc ttcaagattc tttccgctag
    12241 atagctacgt aatccgctat gacagctgac gatatattct tgttggctgt ctaattcatt
    12301 taatcggtcc cgaagttcat tcaaagggat atgtttggct tccttgaatt tgcccttttc
    12361 caattcttct gctgttcgca catctaataa aatttttcct tttgctagtt ctgtcggcaa
    12421 ttcatgccat tgtacggttt cactaagccc ttctgcaatg ttcattgctg catatcctag
    12481 catgtttact ggatctttgg ctgagccaaa tggcggtgca tacgtcaatt ctaattccgg
    12541 taaatcgaag atcgtcaaat gccctttgat tgctgttgct aaaatatcga tccgtttatc
    12601 cacacctttt gccccaacac cttgtgcacc ataaatctcg ccagtctctg gatggaagat
    12661 caacttcagt aaaatatctg ttgcttctgg ataatagctt gcatgatctt ttcctgatac
    12721 atgaatgact tcaaaagaca gttcgttttc tttggctgtt ctttcactta aaccggtgga
    12781 tgcggcagtc attccaaacg ttcgtataat tgctgttcca ataccgcctt gatttcttcg
    12841 agaaattccg gaaatcgtgt ccgcaacttg tctaccttga cgattggctg gtgaagcaag
    12901 agaaataagt gcatcttttc cagtgatttg ctgttttaca acgatagcat cccccaccgc
    12961 ataaatatca ggaatattcg tttgataacg ttcgtctact aggatacccc cgcgtatgcc
    13021 taattcgatt ccagcggtca ctgctagctg gttatcagga cgaacaccaa tggataaaat
    13081 aactaaatca gcagggatgg tacgcccatc atccagtcgc aatcgtttcc cgtggtcttc
    13141 aaatccagcg acagcatgag aagtaatcac ttctactcct tgatgagaca attctttttc
    13201 tataaaagct gccatttctt catccagtgt tggaagaata tgtggtgctt gttcgatcac
    13261 catgacttct aaacctcttc tttttaggtt ttctgccatt tccaatccga tgaatcctgc
    13321 accaacgatc acggcacgct ttggctgttt ttctaatgca tgcatcactt tatcgatatc
    13381 tggtacattt ctaatagaaa aaacattgtc ggcttctgtt atccctggaa tcgatggaac
    13441 aactggtttt gcaccaggag ataaaaccaa tgcatcgtac tgttcaatgt gtttttgacc
    13501 ctcatgtacg acttctaccg ttttgttttc gggaaagatg gctgtcactt catgatttgg
    13561 acgcacatct aaacaaaaac gagcggataa tgattctggc gtttggacaa gaagattttc
    13621 ccgttcactg atttctcccg aaagataata aggcaagccg caatttgcaa aagaaacata
    13681 cggtcctttt tcaaaaacaa cgatttctgc atcttccatt aatcggcgaa gccgtgtagc
    13741 agcagacatt ccacctgcta cacctccgac aataacgatt ttcatcttat ttccctccta
    13801 ctgttcgatc aaaccattga ttcatgccac cacgtacatt cactacatca taaccagatt
    13861 tctttaattc tttagctgct tgtttactcc tcatccctga ttgacaaatc acatagacgg
    13921 tcttttcttt gtctccatca tatctgttta tactttgtaa tggaacattt ttagctcctt
    13981 ttatatgccc gccccggtat tctgcaggtg ttctaacatc aagtaacgct ggattttcca
    14041 aaagcttttc ctttaattct gggactgtta tcgattttat tgattgaaat agcaaattca
    14101 ttttctgcac ctcatttaca tttttataaa tacctcatgg ggtatattaa acaggagctt
    14161 tattaatatg tcaaccagaa tgactcttca tttttttcac tactttttat atttgcataa
    14221 aataccgata aggggtatta tctaattata aaaatagagg agaatgtgtt atggagattg
    14281 ataataaaaa tatcctgaac cgtttgaaac gtacagaggg acaaattcgt ggtatccaaa
    14341 aaatgatcga agacgaaaaa gaatgtatgg atgtcatcac tcaattaagc gctgttcgtt
    14401 ctagtattga tcgcgtaatg ggcatgatcg ttgcagataa tctgaaaaat tgctttgaga
    14461 aacctgatag taatccagaa gaacaagcgg ctaaactaga acaagcgatc aagatgatta
    14521 ttaaaaagta aaggaatgat ttcaatgaaa gtcgttttcc atattgatga attagaaaaa
    14581 tggtcagaaa cagggaaaaa cgtaaaaaac ctgataaaag cttctccaga aacgacgatt
    14641 gtcgtatctg taaatggcat cgcgattacc ggttatctag actctgccaa tgcagaattc
    14701 ttagatttgc aaggagtcgt ttttcacgct tgcgccaatg ctatgcgtgc taatcatatt
    14761 tcagaaagtt ctttacctga acaagtaatc gttgtaccag caggtgtcct tgatttagtt
    14821 gaactgcaat cccaaggtta tgcttatatc aagccttagt cagtagaggt tgcgacagaa
    14881 gtgatcagct tcaagaaatt tcggcttatt tttcgaagaa gctacttctg gaaaaccgtg
    14941 aatcaaaggt tgtgaaaacg ctgtcctgca tcaagtaata agaacagcca aacaaaaata
    15001 gcttctcata tttttcgttt ggttgggctt attaccgcag atgcaagctt ttgaacaccg
    15061 tttaaggaag aggttgtgaa atcagcggtt tgacctaagt attagagaaa aaaacgggaa
    15121 aatagctcct catattttgc cgttttttga gctaataccg aaggtcagct gattgaacac
    15181 cgtttaagga agagattgtg aaaaagtcgc ttagtttcga gtattaagaa aaattttgtg
    15241 aaaatggatt tctacatttt tgcataaatt tggcttaata ccgagaaact ggcttttgaa
    15301 taccgtttaa ggaagaggtt gtaaaatcag cggtttgacc tgagtattag agaaacaaac
    15361 ggaaaaatag ctgctcatat tttgccgttt tttgagctaa taccgaaggt cagctgattg
    15421 aacaccgttt accaagaggt tgtgagccta ccatttaact ccgaatcaca agaaataatt
    15481 tcaaaaacaa cttctcctgt ttttggttcg gttggcttat tatcgagaag tagctactgg
    15541 gagtctattt atcaaaaaaa ggaatgcgac ataggtcaca cccctttttt attttctttg
    15601 aaacatcttt cggtactcga cagcatacaa gacaaaagat tgtaaaagac cgtaagtgat
    15661 gacggcaaaa atgactctca cccacagcgt tggtaattct gggaaaagca gcaaaaggat
    15721 catgccaaca tagatgacag cagtcgctac tttgccatac cacttcgctc cacttaattt
    15781 gatattttta gatagcccga ttaatccagc tacaaacata aagccttctt ttatcaagaa
    15841 tagaccaaac aacagccaaa gccacggtcg ataccatgcc atagacaaaa tcagaaaaag
    15901 ttgtgtcaat ttatctgcaa acggatcaag caccttccct aagtctgtta cctgattata
    15961 tctccgagca atgaccccgt ctagataatc agacaaacct gagacaacaa tgaccgctcc
    16021 tgctatataa aatgactgtc tcagcacaaa ataaagataa atcggcagca aaaaaatacg
    16081 gaatatcgat aaaagattcg gaatcgtttg tatttcttta cgccagtctg tgcttaattt
    16141 cattttatcg ccctacctcc tcagcactct tttcttttta ttttagctta cacggggaat
    16201 aaaaccaatg atttcactgt ttttattttt ctttacagac actgatatta tgagctaatt
    16261 tgagataatc acttgctgtt ttcatcgttt actcttcttt cttcctgtcg tttgcgcatt
    16321 tcttttacta gtactttatg agcttttttt gatcctcgct ctaggtcacg ctgccgttta
    16381 cgtgttttat aatcgataaa cagactgtct aaatcgtaac ctgtcgggta cagatcttct
    16441 gctgaacgca ccagacgaac acgctgacga ggcacgtgga ttattttttt gtctaaatat
    16501 acatcaatcg tatcttcacc tatatcttca taaactaacg cttctttttg gtattcattg
    16561 acaaatatcc gatcaccttt tgcaaagagc tgacgttctt ttttattctc cttcctattt
    16621 gtaactgctg tcttaggaag aaattctttt ttctgtgtcc gataggcttt ttccgccaag
    16681 taacgctctg cttgatggat caatttcatc gacatatcca ttttatgagc aatccacaaa
    16741 gcttggcttt ctcctgtttc ttccaacccg caactgatat ttaggacgaa gtgcttcccg
    16801 atcgaaagcc atagcagccg gcacaaaatc ttcatgatct ccggcgaatt tcttgatttc
    16861 tccataatgg gtcgtggcaa tgatcaatgc cccttgctca tacatagatt ccatgattgc
    16921 gatcgctagt gcagcccctt catttggctc tgttccactg ccaatctcat ctaaaagtac
    16981 caacgtattc ctttttatct ttttcaaaat agcagcgatg ttttgcatat gaccagaaaa
    17041 tgtactcaac gcattttcta aattttggtg gtcaccgaca tcgacgaaaa tctcatcaaa
    17101 gacagcaagc tctgtccctt cttttgccgg aacttgcata ccgaacatcg ccatcaaagt
    17161 caataaaccg actgtcttca acacgactgt tttgcctccg gcatttgctc cggtgataat
    17221 caagcctcga tagtctttac cgatttcaac atccaatggt accgcatgct caggtaaaaa
    17281 tggatgtctg ccttgcttga taatgatatg ttccgattta ttgattctag gtgtgcttcc
    17341 attgatttct cggctaaatt ttgcccgagc aaagatgata tctaacaccg tgatcgtttc
    17401 gatcaataaa tcgatcactt cttcgttttc tgcgatagca ccagtcaatg ccgccaggac
    17461 ttgatattct tcactgattt cttcagcttt taacaactga tagtgttcat tcaatttaga
    17521 aatcacagtt ggttcaataa aaaccgtcgt tcttttattt gattcatcga taatcgttcc
    17581 atctatttta tttttatagc tggctttgat aggaatcgta tagtattcgc ctttttgaac
    17641 aatcattgct tcttggatca tttctttgtt tttcggatga cgcaagaatt tcagtaattt
    17701 tgactggatt tctttttcga ttagttgtaa ttgtttgcgt actttacgca aattacgtga
    17761 cgcgtcgtca ctgactttat tattttttat tttctggtca atcaactctt ctacatttat
    17821 caaatcagga agatgtttgc tataagcaaa caacaagggt gtctggtatt gattcttatc
    17881 aaaaaacttt gtgatcatcc gactgcttct aagaaaatcc gcatattcga tcaaatcggt
    17941 tggctgcaga atcaaccctt ttttgacttg ttctgtcagt gcatcgatcc tcggcaaccc
    18001 cataaatgga acatgctgac tgctttctaa gatcaagcgt gcttctcttg tttcttcttg
    18061 acgatccaag acagtttgta ggtttgtcga gaccgtcata tcgctgattc gttttttgct
    18121 atagtttcca attgctcttg cttggatttc ctttttgatc cgatcaaatt gtaattgact
    18181 aatcatttcg ttgtccatat tctctccttt tcttgaagag atacctgtcc caaaataaat
    18241 aagggcctag agataaataa aaggatagaa cacagcttaa aaaagtcatg tcctatcctt
    18301 attagaatac aaagatattg ttttcctgac aggtaccgtt tcataagcac accaaataaa
    18361 ctttgtttat tggctattcg acttactgat tagataccag ctacactcac aaaacatacc
    18421 ccattcttct aggtcttatt tattttccac ttaactatag caagacacat tttggttgtc
    18481 aaactttagt atgttttata gatttacacc attaatgaat agacacctac cgcgataatt
    18541 gctccgatca ttggacctgc gattggtacc catgaatatg cccaatctga agttccttta
    18601 ttagctattg gcaataccgc atgtgctaat cgaggaccaa agtcccgagc agggttgatt
    18661 gcatatcctg ttggccctcc taatgaaaga ccgatggcta agatcaatcc acctacagcg
    18721 aatacgttcg ttccaggtgc aaattcgttt tgtccaaaag ctagcaaccc aagaactaat
    18781 acaaatgtac caattaattc tgtgatcaca tttgctggat aattccgtat agcaggacct
    18841 gttgcaaacg ttcctaaaat cgcgctttca tctttcgttg cattccaatg tggcaaataa
    18901 gaaagccaaa caagaatggc ccctgcaaaa gctcctaaaa cttgcgcaat gatgaaagga
    18961 acgacaagat tccaactaat tgcccctgtc atcgccatag ctagagagac tgcaggattc
    19021 aaatgagctg ggcccatgaa tccagaaata tagacagcca ttgttacagc gagtccccaa
    19081 ccaaatgcga tgacaatcca gccagaagcc tgtgctttac ttttgtttaa attcacagcc
    19141 gcacacacac catctccaag caaaactagg atcagtgtcc caataaactc ccccatgatt
    19201 tgagtcatat cactgttcat ttatttctcc ccctttagtt cccgcagatc tgattctgca
    19261 atcaatgctt ctaaacgttt agtctgttgc gccttctcct cttctgtcca ttcaaaatat
    19321 ccagcaattg catcgatcac aggttgcttg atctcatcaa gctgatctcg ttcaaacaac
    19381 agatgatttg tacgacgaat gagataatcg cctggggcca aaaccatttc ttcttctaaa
    19441 ccataacgta accgagctga ctcagcgaga ctcaaaccag gataaggtgc catttctttt
    19501 gctaattcaa agatacgtcg ggcattagtc ccgtaaaaat cagcgatata agtagcatct
    19561 tcttcctcta aaccggctgc tactccttct tttgctaatt ctgtcactgt ttcttctaat
    19621 ttagttggat cgaagtttcc acctgaaatc tgatattttt tagagtcgat ttctttcgtc
    19681 tctattccgt attcttcttt taataattgg cgtatcaatc gcaaagctcc ttctgccatc
    19741 ttacggtaat cggtgatttt cccaccagat aaagtcagca aaccatctgg ttctctttct
    19801 aaagaactac ctctggaaat cgtagaaggt gctttttcat cacggctgtt ttccaaatgg
    19861 ttcaacacgt cttctacttc agcacgagaa actttgtttt ccttatattc acttactgta
    19921 tcgacaactt tattgaagct cttgtctgaa atcgatccat tatctccacc attgtaatca
    19981 gaaccagaat taccaatcaa cagtggacga agtcctgccc agcttgcttc gatatcattc
    20041 aatgtgatat ttgcttctgg atagcgatga ttgatcacat ccaatagata atctacatct
    20101 tcttgtgtga ctttcggatc cgtaaaatct ccttggtaat ccgtatctgt cgtaccaaag
    20161 taagtcttgt tttctcttgg aatagcaaaa accatccgcc catcttgctt tcctgtatcg
    20221 aagtatgtgg gttgcggtac aggcagtttt ttcgcatcta caactaaatg gatcccttta
    20281 gttggacgca ttttaggaga gactggacgc gtaaaattca agtttcgtac tttatctacc
    20341 caaggaccac tcgtattgat cactaatttt gctttgattt cgatcacttc atctgtcagc
    20401 aggtcacgag ctttgacgcc aacgatttga tcgccatcat ataaaaagcc aaccgctttc
    20461 attttactta ctagataagc cccatcttcg gcagcctttt tgatattatc aatcactaaa
    20521 cgggcatcat tgttgcggaa atctagatag acacccgcgc cttttagccc ttcttttttc
    20581 aaaaacggtt ctctttccaa tacttcttct ggtgtcagcg tataattctc atatttggtt
    20641 cctgtcacat ttgccagttt gtcataaagg tccattgcta ctttgaccga gaacatattg
    20701 aaggttgttg ctccttcgcc ctcatagatt ggcaaaagca ttggatctgg ttttgggatg
    20761 tgtggggcaa tactttgtac gactgcacgt tcaccaactg tgtcagctac tacttccaca
    20821 tcaaatgtct tcagataacg aataccgcca tgaacaagtt tggtcgagcg agaggaagtc
    20881 ccttctgcaa aatcctgcat ttcgatcaat cctgttttga ttcctgatgc tgctgactgg
    20941 actgccacac cggcaccagt gattccgcca ccgatgatca acagatccaa ttcttcttgc
    21001 tgcatttttt gaatgctatc ttgtcttgtc ttgtttgaaa acatatggat ttcctcctta
    21061 ttcaaatgct tgggtagctt ttactgcttt tttccaaccg ttgtaaagtt tttctcggcg
    21121 ctcttcctcc atttgaactt caaatagctt gccagcttca taaaattcgc ggatctcgtc
    21181 tgtatctttc caataaccga cagctaatcc tgctaaaaat gctgccccta gcgccgttgt
    21241 ttccaagttt tctgctcgtt ggatcggtac attcaagata tctgtttgga attgcatcag
    21301 atattcattg tttgctgcac cgccatctac tttcaataca ggaatcttga ttccagtgtc
    21361 atcttgcatc gtatcgatga tatctctcac ttgataagca atcgactgta aagtagcttt
    21421 aatgatatct tcttttgtcg taccacgtgt caagccaaac atagcccctc gtgctgcctg
    21481 atcccaataa ggagcaccta gcccaacgaa tgcaggaaca acataaacct catcttcgct
    21541 tgtagagcgt ttcgctgcgt cttctgaatc gctagctttt tgcaacattt gaagtccatc
    21601 tctcagccat tgaatcgaag aaccagccac aaaaatactt ccttctaaag catagtaaac
    21661 ctttccattt atgccgtaac caattgtcgt caataaatta tttttggata attgcggttt
    21721 ttcaccggta ttcatgacaa taaatgaacc tgtaccataa gtattcttga ccatgcctgg
    21781 ttcgaatgcc atttgtccga ataatgcggc ttgctggtct cctgccatcc ctgaaattgg
    21841 tgcttcgctt ccataaaaat gataaccttg cgtataacca taaacttctg agttagaagt
    21901 gacttttggt aacatcactc gaggaatatt tagtaaatct aaaatctcct gatcccaatc
    21961 tagctgatgg atattgaaca acatcgtccg actggcattc gagtaatcag taacatgtgc
    22021 ttgtccatcg gtcagtttcc atactaacca agaatcgatc gttccaaaca tcaattcgcc
    22081 tttttcagct cgttcttgcg cgccttctac atgatcaaga atccagcgta tcttcgttgc
    22141 tgagaaatag gcatcgatca ctaaccctgt tttttcgtgg aaaaattctt gatagccttc
    22201 attttttaag ttatctgcaa ttccagctga ctgtctggat tgccaaacaa ctgcatgata
    22261 gattggacgt cctgtatctt tttcccatat tactgttgtt tcacgctggt tcgttatgcc
    22321 aatcccagca atctgatttg gtttgatccc tgattcgatg aacgctccgg caataactga
    22381 ctgtacagaa ttccagattt catttgcatc atgttccacc caactttctt gcgggaaata
    22441 ttgcgtgaac tctttttgag aactgccgat gtgtcttcct ttcttgtcaa agataattgc
    22501 tcgtgagcta gttgtacctt ggtcaatcgc catgatatac gttgattctg tcattgtgat
    22561 tccctccatt atatgcaaac gctttcttta actactctta tcatactact gttttaaaaa
    22621 aagaaactgt caaaatttta ttcttttttt ctttttttga cagtttttta ttatgaagct
    22681 attttttaat caattctttt cttttttcag cgtctctatt cttcttttca atcgaataat
    22741 gtcgtaaggt gacgcaaatt ctgacagata atattcacac tgttttttgt ttctctggca
    22801 aaatgtgatc accaaatcat attctttacc ttcttcataa cttccaatct caataccgcc
    22861 gattcccctc agttctctga tcagatattg ttgaaaagca atacgataaa tcggcagact
    22921 ttctaaatcg attccaatca ctactggttt tgcaatataa aaatcgatca tcaaaagaac
    22981 attggcatac tggatcatca ggtaactaag ctcactatct tcagctcttt tcctcggcaa
    23041 ttgctgcacc gctgtttcct gtaatttcgc cagtaactgt gttaaggaat gcccgagcat
    23101 tttctgctgc tgttccaaaa gccgatcacg ctcatagact tcgatctttc caacaaagaa
    23161 aaaccattca ttgttgatct gggaaatttg gtagcctact gccttttctt ctttgatttt
    23221 caaacgacga ggacgataat gccataacat cgtttcccga atgtaagtat ctaaaacagc
    23281 ggttggtaac tttttgctcc gtgtcaaatc atactgataa aatatttctt cgtctactat
    23341 cgaaaaagaa acaaaaaagc tgtaaaacat cattgtttcg tatacattca gttctgctgc
    23401 tgttcgacta agatgcatca cgatgattgg atcgattgct tgataaagcc ggtccgactg
    23461 atagagtaat ttcttttctt tcaaagttgc gtacgtactt ttttcattca atagtctttt
    23521 tttcgtaatc ccgagccagc aagcaatctg tgcttctgct gatgccgtaa acgttgtttc
    23581 taatacacgg tccaatccta gaatgaacgg tcttttttct ggtgtatttt gcaaaaaaag
    23641 cggtcgctga tcttccggga tatattggaa tagttcataa taaaaatatc gtatctgtag
    23701 ctcttctccg tataattgac cgtttttgat ttgtaatcca aattcctcta agagctggtt
    23761 caattctttg atctttcgaa aaacagaaga ctcactgata ttaaacgctg tcgctaatcg
    23821 aacgatggat acttgctgat gttctaataa atagacgagc atcttaaact tcaagctttc
    23881 ctgcaataaa aacaatagaa ttttttccaa acttacatct tcgtccaaca caagcagcgc
    23941 ctgatactca tttcgctgta cttctacttt tttttccatc attcggccaa tcaattcaat
    24001 atcttccaaa tattgatcaa acgaggcttt tgacagttgg acatgctctc tcaaaccatt
    24061 gatagaggct gttccccctt gcagaacaag gtttcgcaaa atcaggatct gtaactgctc
    24121 ttttctttct aataatgctt caatcttcat aggcagtatt cgccaccttt gaccacacca
    24181 tatctggcac acggtattct ggctggaaaa atagctcatg ttcttctaac tgttcaaacg
    24241 tccatccttc ttctactgca attgtcagtt ggtcaagaag gtggaacatc tcttttttgc
    24301 tttggagctg tgctccaaga atcttttttt cagaatcaaa tagaaatttg agtttaactt
    24361 tgctttgatt tattgctgta agcttgtagt ctacgtatcc tgtttcaatt ttttggggat
    24421 aaaaaatgct ctcttcttct gtcaaaccta cgcttcctaa gaaatagcca aaccactgat
    24481 tgccgactgg acgataggtt ccctgatcct ttgtctgtga gccactaatt gtcttgctga
    24541 catttcgtgc tgtacggaca gcgttattta ctagagaaac atacattttt tcatttgttg
    24601 gacgaaaagt tacttggatc gcatcgccaa tcgcataaac gtctttttga gacgtttgca
    24661 agtagtcatc tacccagatc gttccatcat cattcaatgt taattgttct tcccacatct
    24721 gattgtcggg acgagaatga ttagccagca aaacaagatc atagttctcc tttctttttt
    24781 ccgtctctac aatagcggtt tcattttcgg tcaaagacac aacttgttct tctaaaaaaa
    24841 gtgaaagccc ttgatttttc atttccttta ctaacggttc tgtcatttca ggatctagat
    24901 aacgaaaaag aattgacttt cggctttcgt aaagatggat ttgttttttt cttgatgcca
    24961 acccttcagc tatttcgatt cctgcttgtc ctgcaccaat aattgcaatt ttctttgcat
    25021 tcatgatctt ttgctgaaga gccgttacgt tttgtatctt tttaactggg tgaataagcg
    25081 ttgattctgc agaaatattt cgaaactttt gatttgaacc agtcgctaga atcaaacgat
    25141 caaaatccaa tttttttcct cctgctaaaa cgactttttt ttctttcaat cctattactg
    25201 tcttttctgt gtaaacatgg attcgatagc ggtcagtcag ttcttctttc gtgatccaag
    25261 aaagttgttt ttcactggta acctttcctt ttaatatcaa attgaacccg ctgggaatcc
    25321 atcctaactt cgattgcttt tcaatcaaat atatttcact tgttggcatc aattggcgaa
    25381 gataaatagc cgcatgaatc cctgcaaacg acccgccgac aattacaatg ttcatctgca
    25441 ttcctctttc ttataaggtg ttctactgct aacttctcaa tcagaaaaca cagtattcat
    25501 aactcgcttt caaccttatg atacatagcg atgcagcaga atcaaccctc tccatcatac
    25561 cgtgttctag gtctgcttct caataatgta ctagtggacc taattgaaga gtatcatttc
    25621 tgaagagatg tttcaaaaaa tgtactctta taaaagaaaa aaactcgcct tttacgtacc
    25681 tctgtccaaa taggaaacag aaaagaacga aaagacgagt tttagcgtgt gtaatgtaat
    25741 agttagaata gacacatcat ttatttttaa ttctttaatg cttcaacaac tgcttcgcct
    25801 aattgatgag cagattgagg attttgccct gtaagaagcc gcccatcaat ttgaaccact
    25861 tctgaaaaag ctgctccaga ctgatagttt gctccttttt ctttcaaagc atcttctgct
    25921 aagaatggta cttcattcgt tgtaccattt gcttcctctt cttcattact gaacccagtc
    25981 actgtacgtc cagctaaaat agattttcca gactcatctg taactggcaa caatcctaca
    26041 acaccgtgac aaacagctga gaccagccct tcatttcgat agatttgtga agcgactttc
    26101 ccaagatcta ttgcttctgg aaaatcccac attgttccgt ggccaccagc ataataaacc
    26161 gctgcataat catttgcatc cacatcatca ggacgtaagg tatttcccaa ggcccgattt
    26221 ctgaaatctt catcttcata ataggcccaa tcgatttcat ccatattcaa aacactttgc
    26281 ggttctaaag gtacatatcc gcctttagga ctgacaaaat ctgcatcgat cccatttttt
    26341 actaatacat cataaaaatg agtcagttca cttaaccaca aacctgtagg acgctcgatc
    26401 ttttcgtact tttctacatt tgttaatacg atcaatactt tcattttccc atcctctttc
    26461 tataaaaatt gcgttattga taacgtgctt tcaagaaatt atataatggg cttggcaaat
    26521 aaagctcttt atatgcttct tcaaaaggtt tcgttacaaa ttcatcctca cggttttcca
    26581 ataatttctc tgcccagtca ggatcgacga tcatttgctg tccaattgct gcaagttctg
    26641 catatttcaa tacctgctct acatcttcgc gattgcggat cccaccgaca ccaactaaag
    26701 ggatctttcc ttgaatcgtg ttatggacca cttcaagaat cgatttatcg ttgtatttat
    26761 cagaacgagc tattcgatca tacatattta atgaaacatg cagataatct agttttgact
    26821 cacgtaatcg ttcaagaagc cagatcgtgt cttcaaaacg gatacctggt gtttcatatt
    26881 cttctggtga gaaacgatac cctacgatga atggtttttt agcatattgt tcaaccgctg
    26941 agaaaaccgt tgttaataat tcttcaataa aacgataacg attttccaag ctaccgcccc
    27001 attgatcctc tcgtctattc gaatgcggag agaaaaattg ttggatcaaa tacgtatttg
    27061 ctccatgcaa ctcgattcca tcaaatcctg attcaatcgc tctacgtgtg gctttgccaa
    27121 atgcttggat tgtttcaacg atttcttctt cactcattgc tcgtggtgtt tccgcatcag
    27181 gacgttttgc tgcaactgca cttgcagata caggctgttc tccagataaa gttgctcgac
    27241 ttgtcattcg tccaccgtgg aaaatctgaa taatcgcttt tgcgccttct ccttggattg
    27301 ctttcgctag ctcacttaat cgaggaatca tttcatcatg agcgatgctg agttcacctg
    27361 gccagccttt tccgatatct tggacatttg cagcaccagt aataacagca ccaagacctt
    27421 tagaacgttg tttataataa gtgatctcat cttcggtgat cactccattg aaaaagctga
    27481 gttgtgtcgt cataggcgac agcatcaatc ggttcttcaa ttgaactcct gaaggtaaag
    27541 taattgattg atcaaattgt gacattgtca ttcctcccat aattcgctct gattaaccta
    27601 tcgagaatca tctatcatta aaccactcga ttagttgtac atgcaactaa tttgcttaaa
    27661 aaattttatt ttttttgtaa cttatctgtt gcatcattca ttgtctgggc taattcttta
    27721 cttgcttcat ttcccaaaac tgctttgtat gactgatgaa gttcttccca gctaccatcg
    27781 acttccttag caaattggcg tccttgttct gtaagataaa ctaatgacaa gcgaccttcg
    27841 ctaactgttt tgacgtatcc tttatattct aatttttcaa caaaacgagc aatcgttgat
    27901 ggggcggaat agagcatttg tgcaatatct ttttgtggta ttccatcttt ttcttttaat
    27961 atcaataaaa taaaaccata agttggtgcc agacctgtcc ttctaaacgc ttcatcagct
    28021 aatttattca acatgcgatc tagctttttc acgctaaaga aaagacattc atctaacgct
    28081 ttttcaattg gcttttccat ttcatcccct ccattggcgt acatatcata gtatgatttt
    28141 tattttttgt caaaaaacac ggaataatgt ccgcctcctc tgtctagatt tgaaaaaaag
    28201 aagtagccat cttcaaagaa tttcggcttg ttttcgacaa aactccttct ggaacaccgt
    28261 gaatcagagg ttgtgaaaaa gtcgtttagt tttgagtatg aagaaaaatt ttgtgaaaat
    28321 ggctttccac atttttgcat aaatttggct taataccgaa aaactggctt ttgaacaccg
    28381 tttatatcag aggttgtgaa aaagccgtcc tgcatcaagt aataagaaca gccaaacaaa
    28441 aatagttcct catattttgt cgttttttga gctaatgccg atggtcagct gattgtacac
    28501 cgtttattga gaggtcgtga gcctgccgtt gaactccgag tcacaaggag caatttcaaa
    28561 aaacagcttc tcatgtttta tgactatggt gacttgtgat cgaggagttg gcaggagaat
    28621 actgtttatt cgtaaagaag gggctgtgac aagacttttg tcacagtccc ttatttcctt
    28681 ttattatagg atttcgccat ttgattggat gacttgtctg taccaatcaa atgatttttt
    28741 ctttaaccgt ttctttgtgc cattcccttc gtcatcttga tcaacataga tatatccata
    28801 acgttttgac atttgtgaag tagaagcgct gacgatatca atgcagcccc acgacgtata
    28861 accaaataaa tctactccat ctttgatagc ttccttcatc tgctcaatat gctgcttcaa
    28921 atagtcaatg cggtaatcgt cttgaacggt tccatcttct tctactttgt ctatagctcc
    28981 gagtccgttt tcagctatga acagtggttt ttgataccta tcatataatt gattcaaagc
    29041 aattctcaaa cccttaggat caatctgcca gccccattca cttgatggaa gatacggatt
    29101 tttaattcct ccagttatta agtttccttg gaccccttcc caattttctg gatgagcact
    29161 gactgcacta gacatgtagt agctaaaaga aacaaaatca acagggtagg ctgctaagat
    29221 ttcttcatca cctacttcta tttttaagtt gacacctttt tcttcaaaca ttcgttgcgt
    29281 atacgctgga taatatcctc ttgcttgaac atcactaaag aacaaagaag ttctttgctg
    29341 ctcaattgtt ttttgaatat catccggatc acaagaatac ggaacaagaa gctgatagct
    29401 gatcatacaa ccgacttgtg aacctttgat aatttcatga caagcttttg tagctaaagc
    29461 acttgctata aactgatggt gtgcaccttg gtatttcgct tgttccaaat ggggatggtt
    29521 ttcttcaatt actcctacgc taacaaaagg gtgatgtttt acacagttga tctcattgaa
    29581 agtcatccaa tattttactt tatttttata gcgtttgaat actgtttcag cgaaacgaac
    29641 gtaaaactga ataagctttc gattaggcca tccaccatat tctgtaacca aatataacgg
    29701 catttcataa tgggaaagag aaacgactgg ctcaatccca tattttagac attcgtcaaa
    29761 cacttgatca taaaaaaata atcccgcttc attgggtgtt tcttcatcac catgaggaaa
    29821 aattcttgtc catgcgatag acatccgata gcatttaaaa cccatttcag caaataaacg
    29881 gatgtcttct ttaaagtgat gatagaaatc atttccgtgt cttttaggat aataatactt
    29941 gctgttggga tcctgcgccg cttttacttg ctgatgcgtc atcatatgcc attgatctgt
    30001 ccatttttct ttaggtaaat cgctgtcgaa tgtatacaca tcagacacag ataatccttt
    30061 ttcatctaca tcccatgcac cttcacattg attggccgct gtcgctccgc cccataaaaa
    30121 tccttctgga aattttttca tatcgatccc cctaaacttg ctagttttct tgtttgatta
    30181 tttttcttat gactagtaat gatatttttg aatctactac tatttgtaac aataaccatt
    30241 gtggtcggat catatccctc tttgattaat tcttgcaaat ctacttccat caataaatcg
    30301 cctttacgta ctttttttcc atcagatact gcactttgaa agtatttgcc atttaaattc
    30361 actgtatcaa taccgatatg gatcagtatc tctgctcctt cttcactgac taccccaatt
    30421 gcatgtttcg ttggaaaaac tgttgaaact tccccgttta cagaactgta gatttttccg
    30481 tccgttggaa tgatcgcaaa cccttctcct aaagatccac tagcaaatgt tggatcgttt
    30541 acttcagata aatcaattat ttcacctgct gcaggagtac ttaacactat atcctttgag
    30601 gattcttctt cgatttcatc cttgtagccg aaaagaaaag ttagcataca ggaactgatc
    30661 atcgctaaga aataactagc aactagccaa acaaatcctt caccaatata aatcgggaaa
    30721 gacaaaatac ttcttgtagc aactgccaaa gcaccggctc ctgcggcacc agctactcca
    30781 ccaaatatag ctccacatat acaagcaatg taaaatggtc gtttatattt aagagtcaca
    30841 ccataaacag caggttcagt gattccaaat aatgctgtga taaatgcaga taaagataaa
    30901 ctttttactt tcttattttt cgttttcaaa aataccccaa gtactgctcc tgcttgcgca
    30961 gctacggcag tcatacatgc tggacctagc gtatcacgac cgtagaaaga aagattgttg
    31021 gtcattactg gtacaagtcc ccaatgtaac ccaaaaatca ctaacacttg ccaaaatccg
    31081 ccgataacag caccagataa aacagggcta aagttataaa cagctaaata tccagctgca
    31141 atcagctgac ttgcataatc tgcaattgga cctacaacta ataaaataat tgggaccatc
    31201 acgatgatac aaatgaatgg tgtcaataaa tttcgaatac tttcgtgcaa gcttttgcga
    31261 atcttaggct caatataaga aagaacccat acagctaaaa ttgctggaat aaccgtactt
    31321 gtataccttg ctagaatcac gggcatccct agaaatcgca aggttatgct atcactatat
    31381 gcactgacaa tcgtaggata aacgagagct gctgcaataa ccatagcgat gaaacgatct
    31441 gtattgaact tttttgcagc agtatatgcc aaaaatatag gcaagaaata gaaaaatgca
    31501 tcagctgctg cattcaaaat gatataagtt cctgattcag tagttaataa attcaaactc
    31561 gtacataagg cgagtactcc tttgatcaaa ccacttcctg ccaagacgcc taaagtcggg
    31621 gcaaaaacag cggcgatcat gtctataaaa gagtttaaaa tgcctttttt ctcagttcct
    31681 ctctttccac tagatgcatc atcttctagt ttcatttgtt tggataatac gtcatacact
    31741 tcatttactg catttcctac tacgacttga aacattcctc cagcttcgac tacagtgatc
    31801 acaccttcta gttgctctac cttctcctta tctgccttct tattatcttt tagggtaaag
    31861 cgtaaccttg ttgcacaatg gtaaacattg ctgacatttt cttcgcctcc gacaaatcgg
    31921 acaatatctt tcgctaattg tgaatagtcc atttttactt cccccttgtt aattaatgcc
    31981 gtagcaatcc ttcttacaag ataagtatag ttcttagaaa acggtttctc cattcaatta
    32041 gtaccccttc taatagcgaa cgaaactgta caatagtgtg tatggtttac ttagccgagc
    32101 aaatcactca ctgcttgaaa gaaaacaagt atatcgtttc tcttatagtc aaaggagaca
    32161 aaaaaaacac gcttgatctt cctttgctga tgtataagtg gtatctcaag ctgatactct
    32221 gtgatttttg tttctacttg gcttttgata agacagcaca acaaagtctc ggcatttaac
    32281 ggaagcataa ctaggtcaga actaggagag attagttgct gaatggaatc tatcttttta
    32341 tggattttta tttgattttc ttctttgtag taatgatcaa gcagttttgt tttctttttt
    32401 tcttcaacta tggtcagctt ttcacgcaaa atctgataaa tctcccaaga ttcaaactca
    32461 tctagaacac taggtagata aatcaaatca tcccactcaa aaataagctc ttgctcagta
    32521 gtcaaaattg catcatattc cgttattttg tttgattgat ttttgaaaag atacactggt
    32581 tctatccggc attctttgat ccacatgttc atactttgtt gaatctgttt ttttagtgta
    32641 ttcaaaatac taattggctg gttactaaca atcagtatct ccccttgttt tcgaaaagga
    32701 ttcaacgctt cggcaagata caaaacaaaa taagcgcttt cagctaaatt gggacgtaat
    32761 tgaaaatgta ttgggaagaa acgccgaatt aaataaattt ctaaaggata acgggagatg
    32821 atcttttgta caaaatgatt catggtatta tgtccggcat ccatcctcgt tttcatttgt
    32881 ttgatatggg ttagcaaaaa ttctgtttca tggaacaata acgaaacagg aagatctaaa
    32941 aaacgaataa tcgtttgctc aaatgctctt agattcttct ctatttcttt gtttttttca
    33001 tcattaatca tcaaataatt taactctaat agtcgatttt caattgcttg tttttcttga
    33061 ttggaaaaag aatagggtag ttctgatgat aacttttttg tgagggtctc taccatcgga
    33121 ataaataatg tatacctgtt tgttttttct aaaagttctt ctcttcgaag aatggtcaaa
    33181 acgagatacc gagaaaatcg tatgaagtcc tctcctgaaa caatataatt atatgatata
    33241 agaacctctt ttaatgtctt ttggacagtc ggcatgatat tggaaaaaat tgtactgatt
    33301 tgttgaggaa accttgcgtg ttggatcacc gtttctgttc caacaagaga taagaaaatt
    33361 ctttttgaat tttcttcagc aatgattttt agtccttttg tcgacgaaac ttccagttct
    33421 aatttaggat tgcgctcgat ccaacgcaaa atcgttttta tttgtaatga tacggctgtt
    33481 tttgaaagaa agaaaatgtc tgctatcttt tgcatactga catacccttt ttgaaacaat
    33541 aagtacgtca caatagttga agctcggaaa tccatgctgg aatagatttt atgtttcgtc
    33601 acctcttgta tgatttgctg tttagtttca gattcaattg attctaaaaa ataacctgaa
    33661 cgtttatttg actggataat gattttcttc tcgtagatag caagcatatt tttgatttca
    33721 gtttggatcg ttttcttgtt ggtacctaaa gcttcagcta attcttcgct tgttatccaa
    33781 tgattcttat ttcttaatac tacaagaatt tggagttgtc gtttatttaa gtccatttgc
    33841 ttacacctcc tctttgttat aaacatacag gaaaaacctc tcaaatgaca atagtcactt
    33901 gcagaggttt aaaaatcatt tgaagaaaga tctatattca aggtttttac cattagactg
    33961 gataatttgt ttataatatt caaaactatc ttttttcaat ctcctaaagc ttccgctccc
    34021 atcattttgt ctatccacat aaataaagcc atatcgcttc ctcatttccc ctgttcctgc
    34081 cgatacgata tcgattggtc cccaccataa gtaaccaatg atttggcaac catcttttat
    34141 tgcctcagca atttcctgaa gatgtatttt tagatactca caacgttttg gatcgtggat
    34201 tcgattcaat tcatctggtg cttcatctag tccaatgcca ttttcaacta tgaataatgg
    34261 taattcataa cggtctgtca attcattcat gacataacga aaccctagag gatcaattgg
    34321 ccaactccaa ggttcgggag atttttcctt caaaaaggga ttatcgaaac catttgctcc
    34381 gccagtatct acgcgcattt ctgcttcttt tttatagaca gcgctacgat aataactaaa
    34441 tgcaatataa tctgccgtgt tagcttgcaa gcactgttcg tctccatcta acattactgg
    34501 tgcacagtct tcttccttcc atgtcctgta aatataagct ggataatgcc ctcggcacat
    34561 gacatcggag aaaaaccatg aattgcgttt aaattgcagt gaaccaaata cattctctgg
    34621 atcacagtca tatgcataag tcgctaatgc agaaaagcta cacataatac ccatcttagc
    34681 atttggatcg attttcttta ataattgagt agcacgggcg ttcgctagaa acatatgatg
    34741 acaggcttga taaatcactt tttttgttag tgtagcaatg ggttcaagtt tatctctagc
    34801 agggaatgta accaatccag cagctgcata aggcatacga aaagcattat tgatctcatt
    34861 aaaggtcatc caatatttca ctttcccttg gtagcgttca aagacggtct gcgcataaaa
    34921 ttcaaaaaag tcgattaatt ttcgattttg ccacccccca tactctccta ccaatgctaa
    34981 gggggtttca taatgactaa gagtaattac tggctcgata tcatatcgat ttaatgtatt
    35041 gattagtctg tcataaaata cgagaccagc ctcatttggc ttctgttcgt ctcctcttgg
    35101 aaatattcgt gcccatgaga tgcttgttcg aaaagctttt aaacctaact ccttcagtaa
    35161 acgaatatcc tcttcaaatc gatgataaaa atcaatcgct tcatgagaaa gataatggag
    35221 tgattcgtct aaagcaatct cccaaatctt tttttcttca ttccactgaa tactaggatg
    35281 ctggttcatg atcccgataa gcgtatctgt cacattaggt aatttgccgt cttccaacca
    35341 tgcaccttca cattgattag cagctactgc tccgccccat aaaaaatttt ctggaaatat
    35401 ttcctgatcc ataactatct ctcctcgcta tcaacaattt cttacttgaa gtatagctcg
    35461 attcatcaaa acaagatatt ctaactattt cggcagaaga gaagaaaaaa attgaatgct
    35521 actcttcatt tttaatattt atatataaca aatacataag acgatccccg aaagaaaaca
    35581 ctcgttaacc atctaagcaa acgatttatt ttacttccaa cacaaatgct tcataaggtc
    35641 gtaaatcaac tttgccgtct ggtaactgtt tcagaggata atttgacaca ataaccctta
    35701 aagcttcacg tggaatagtg aacgtctgct tttcactgga catattacaa ataacgagcc
    35761 attgctggtc ttcatatatg cgagaatagg caaagacatg ctcaggcgtc ttttccacta
    35821 attcatagtc tccccagacg atgatgtcat gttttctacg caaatcgatc aatttcttgt
    35881 acatataaaa aacagaatct tgatctgcta acgcttcttc tgcattgatt tctttataat
    35941 ttggattgac tcgaagccat ggaattccag tagtaaaccc agcatgttca cgggcgttcc
    36001 attgcatagg cgtcctagca ttgtctcttc ctttcgcctt gattgattcc aagatttcct
    36061 cttttgtaaa tccagaagaa atcctttcgt tatacatatt gattgtctca atatcttttg
    36121 cttccgcgat atcatcgatt gggcaattcg tcatgcctaa ctcttctcct tgatagatat
    36181 aaggggtgcc tttcatcata tggagcaaga tagcaaacat cttggcactt tcttttcgat
    36241 acacatcgtc atttccccaa cgagaaacaa ttcgcggaag atcgtgatta ttccaaaata
    36301 aactattcca tccttcatca cctaaagatg tttgccattt ggataatact tttttcagtt
    36361 cagagatact caagggtttc aaatcccatt tgtctttgcc ttcttgctga tctaatccta
    36421 tgtgttcgaa ttggaagacc atggataatt catttctttt aggattggaa taaagtttag
    36481 cgatttcggt agttgctccc catgtttcgc caacagtcat cagatttttg tcaccaaaag
    36541 ttgcttgatt catttcctga agatactcat gcagtttagg tccattactt gtgatttctt
    36601 tatccggttc tttgccaatc atatcgatca cgtccatacg aaagccccca atacctttat
    36661 cgatccagaa attcatcatt tgataaatct cttggcgaac ctgtttattt ttccaattca
    36721 aatcaggttg acgcttgcta tacaagtgca gaaaatattg ccccgttttt tcatccaact
    36781 gccaagcaga accactgaat attgagcgca atctattagg ctcttttcca ttgaccggat
    36841 cacgccaaat ataatagtcc cgataaggat tttctttatt tttacgggcc tcaatgaacc
    36901 acggatgttc atcagaagta tgattcacca ccagatccat gatgatacgg atatttcttt
    36961 tctttgcttc ttcaatcagt tcttccattt cttccatcgt accgaattct gccatgattg
    37021 cttgataatt actgatatca tacccattgt catcattcgg agactcgtat actggagaaa
    37081 gccaaattgc atcaatacct aaatacgcca gataatccaa cctggaaata atcccccgca
    37141 aatctccaat accatcttga tttgaatctt gaaaacttct tggatagatt tgataaacaa
    37201 ctgaatggtg ccaccatttt tgttccatga ttttcctcct ataaatggat gtttctattt
    37261 tttgcttaat catttatttt agtctctctc actaaaaatt gtaacgcttt caaatagcta
    37321 ttgcaccttg ttatcggtaa cagaataaaa caaaaaaaca gctgaggaaa ttccctcaac
    37381 tgttttttga aaggattgat ttatgcaggg aagaatgctg atttcacaac ttctttataa
    37441 acggtgttca ctcagctgtc ccttggtatt agctcaaaaa acggcaaaat ataagaaact
    37501 attttttcgt ttttttctct aatactcagg ccagaacgct gatttcacaa cctctttatt
    37561 tcacattcaa tatccacatg aatcccacaa atacaaagaa cagaccatac atgattggag
    37621 atacttcttt tcctctttta gctgctaaca tggtaattgg atagaagata aaacctaatg
    37681 caatcccatc tgaaatacta taagtcaaag gcatgccgat caagatcaag aatgaaggga
    37741 tcgcaatctc taagtttccc cattcgattt gtcgcaaaga ttgtgccatc aatactccta
    37801 ccataatcaa tgctggtgca gttacttgtg aagtaacaac tgatagtaat ggagaaaaga
    37861 acaagcctaa caagaagaaa atccctgtag taatagctgt gatacctgaa cgtcctccaa
    37921 cggcgatacc agctgatgat tctacaaatg caccaacagg agaagtacca aataaggaac
    37981 ccgcaagcat agctgttgaa tcagaagcta aagctttccc tacacgaggc atcttgttgt
    38041 ctttcatgaa acctgcttgg tttgctaatc caactaaagt tcctgctgta tcaaagaaag
    38101 tcacaagcaa gaatgtcagc actacgaccc acatttgaag agaattgatg tcccctacat
    38161 gttttaatgc aactaaaaat gttggtttca aacttggtgc tgcggcaaca atttcagaag
    38221 gcattggaat caaacctgtg accagaccta aaatcgttgt agctgccatc ccgatgaaga
    38281 tgccacctgg tacacgccga acaagcaaga tagcagttac gactaatcca aaaatcgtca
    38341 accaagtaga accaacgttg agtgatccta atcctactaa tgtagattca ttcgaaacga
    38401 tgatcccacc ttcgctcaga ccaaggaaag cgataaatag accgataccg ccagaaatcg
    38461 catatttcaa atctgctggg atcgcatcaa tgatcatttc ccgcagcttg aagattgtga
    38521 tcaaaataaa aatcaaagaa gcaacgaata cgccggctaa tgctgtttcc catggaatcc
    38581 ccattcctaa acaaacagaa taagcaaaaa aagcattgat cccaagagca ggtgccgttc
    38641 caattggata acgggctaat acccccatta aaacacagcc gatcgcactg gctaatgcag
    38701 tcgcagtaaa cactgctcct tcatccattc cagaagcacc taatacagtt ggatttacaa
    38761 ataagatata agccattgag ataaatgttg taaatcctgc cagtacctca cgttttaccg
    38821 tggtgttcaa tttttctatt tcgaagtagg aaagtatttt ttccttcatc ttccatcccc
    38881 ctaaatccga acattataaa taaagtccgt taaaatttcg atttattaat aaaacaacgt
    38941 gttttatcat atactaaaac aaaacataag taaacaaaaa attcggattt taagcaaaat
    39001 ccgaacgttc catctgatta aatcccttta tctcaaagtt catgaacatt cactttggat
    39061 tacaagaatt tctttattgt gttaataaag tttcttcatt ctagtctcaa aaatcaatag
    39121 tgtgatttga ttttaccatt tcgtttctgt tcttctttga tgaattcttt tgtatcgaca
    39181 ggattcagat tatttagtcc gccaaaacct gtatcgacca tttttcccca gccttttgtc
    39241 ttcttttttc ctgatttgag attctttgct cgaagcttct cactatgttt tgctcgccga
    39301 tacttcaaat aaccttctaa tcttcccatt agatccactg tttttcctcc tttttattca
    39361 atcagacgac tcagcttttc ctataacaaa ataattgcct tcagggtcag aaaaattgaa
    39421 agtcaagatg ccattgttat ctgtgatttc tcctggttct tccatgttct cgtagatagt
    39481 ttcaaattca tccgtaaaaa atactaaaga aggcggtggt cctaatacct ctggtgaaaa
    39541 cttctgcaca aatacttttg ggaatacgcc taattctaat tcttttgaga tgctgagtac
    39601 aatactctta aattcttctg gcaattcgat tgtttcagaa atttctgcac caattttttc
    39661 tacaaagaat cggcaaatca tctctacgtc attgacataa agcatcacac gtgttttttg
    39721 tatcatcatt tgacccttct ttctatttga ttttctttcc tgtctataaa ctgattccat
    39781 tatatcacga aagcgcaaac accttgtgtt tgatactatt caagaaaaat aaagcaatag
    39841 tttctaggat tgctttcctc cacaaacttt ttttacaaaa aaaaaacggc aatgaatgcc
    39901 gctcttctta tttcgattct tttataattc tgcttctgat tcatctttgg ttagtgtgtg
    39961 tctaacacta gttacgccaa atgtttgatc gattttttcc ttcaacgctt cgattgcctg
    40021 tgcgccacgt gccgcttgtt cagcattgat ggattcaatg accagcaccg ctgcttgtgt
    40081 ttcttccgtc agcatcgttc tttgggcttc acgccagttg agacagcgac agatcgctcc
    40141 ttgttcatca tagtagatga tttcttccgg aagtgccgga gcatcggaat ctgcacctaa
    40201 aggcaggaat gattcgccac cttgggcttt tcctaaatgc agatttcctg cgatcttttc
    40261 gatatcttct ccgccgcaag gtacgccaaa agacaaggaa atactattat agatatctac
    40321 aagcggattg attgggaaaa attcccgttc ttgatttgca cgtttcagta aagcttcaat
    40381 agaagaacgt gcaccttttt tagtcttgaa tgtggtaaat gcctgacgcc actgagcaat
    40441 gacttcgttt tggctgaatg tttcttctgt aaggtaattt cttgcttctt ttgctgcctc
    40501 attcaataat tgatgatacg tttcttcact ttcttttgtt acgtggttat cgataccatt
    40561 tacggataag atttcgatgg ttgcttcagg aaatacttcc cagaaattgg tatccactat
    40621 tacttttttc atctgttcac acctcttgat tagaataatt gcttgatgaa tagatagtct
    40681 gtttggggat catctcccat ataaaaaaca tgttcgctgt atttgataaa tcctttttta
    40741 cgataaaaag cgagcgcaac atcgttgtgt tcccaaacac cgagccaaat ggctgttttt
    40801 tgcttttctt ttgctttttc aatagctgta tctagtaaaa atgtaccgat accttgatgt
    40861 ttaaattttt ttcgtacata gattcgctcg atttctaaaa aatgatcagc catttcctca
    40921 gattgactcg ttcctgtatt tagtttcagg taacccgcag gctcttgatc gatactcact
    40981 aggaaaaaat cggtttcttt atcttttagc tcttctgtaa gtttttctag tgcataagct
    41041 tgtgtcaagt aatcagctaa atgctccggt gaattatctt ttccaaatgt atctgtaaat
    41101 gtttcgatac taatttgttg tagtaagtct acatctgaag gcgtcatttt tcgaatttcg
    41161 tatttattca cggcttcttc ctttcaatag atccttttat tgcctttttt gacaaaattc
    41221 caatcttcgc taacattctt gcatacttta tttaaaagat attccaattg ttttgcttct
    41281 tcgtcagaaa gaccatttaa tgcgactgca ttggagtagt tgttttctcg aatgatgaaa
    41341 ggatagattt ctgctccttt tttagtcgga tagagtttct tgattttttt attttcttta
    41401 tcttccaaac gttcgatcat cccattggat tctaatttct tgattgctcg ggcagtcgtt
    41461 gtacgatcta ctttgatcat ttctgctagt ttttcttgga tgattccagg attttcgcaa
    41521 atacgtacta aataaagata ctgtcctctt gttaaatcga cttctttgaa ttcgatattg
    41581 ctaatagaat ctagcgctcg ggcaatcatt ccgatgtctc gaaggatttc agccatttca
    41641 tcccaccttt attttgtttg taagactagt tcacctcttt ttgttgcaaa tgcaactatt
    41701 ttcaataaaa aaatcaagtt cttttttaat aactagtaaa gtatattctt ttcttctttt
    41761 acgaaaaagc tcaatcacaa tagatctggt ttttgttttc taaaataagt aactgtttct
    41821 tcgttgttcg cttttctgat agctttggca actcttctat actaaaaaat cccatgttgg
    41881 aagtttcatt attctcaata aacttggcct cttcaccgtg gatcgcacaa gcaaaaacaa
    41941 gtttataata ctgaaaaagc tgtggaatat ctttttgttt attcgtatca aaaactgctc
    42001 gcaactgagt agtttctact gttaatcctg tttcttcata gacttcttta cgcacatttt
    42061 cttcaggaga caatcctatt tcagcaaatc caccaggaag tgaccattct ttcgtccgtt
    42121 tatcttcgat tagtaggacc ttgccatctt ttttgatata ggcacgaaca tctacttttg
    42181 gtgttggatg tccttctcca atcgttgtga gcgcttttat ttcttcgaaa gtttcttttc
    42241 ctatttcact gatcagttcc aatgaaatcg tccggatctc ctcaaaacgc tctttatcaa
    42301 atacatcttt tccataatat agaccagctt gagaaagtgc gagtagtctt ttgtattgag
    42361 ccaacttctt gttcattctc ttcccttctt ttttagcaaa tgtatgacta tgtaatcaag
    42421 tatagaagac tggtttaatt acggcaaata aatataatga aatctgcaat aaataaaaga
    42481 atgttaaaaa actcgagaac aaaagacatt cgacttctct ggggctgtga ataaatggcg
    42541 ttcaaaagct tgcatctgcg gtaataagcc ccaccaaacg aaaaatatga cgagctattc
    42601 ttgtctggct gttcttatta attgaggcag gacagctttt tcacaacctc cccactaaac
    42661 ggtgttctcc taccaactcc tcggtcacaa gtcacaatat tcatcaaaca tgagaagctg
    42721 tttttttgaa attgctcctt gtgactcgga gctgaacgac aggctcacga cctctcggta
    42781 aacagcgttc aaaagccaat ttttcgatat taagccattt ctttgttact tattgtcatt
    42841 gatttctttt tctaatttat ccaatagtgg agtgtaatcc acttgagtat agtctgttac
    42901 atcaaattca tatagtgttc ctaactggaa tttgtcatat tttcggtcgg cgatgatctt
    42961 tttgaatgct tctttcgtaa tatgattggt ccctttcgtt cgatcttcca atacgtcacc
    43021 atagtgataa tgatccatga tatagctcaa atgacgatct gattcacgat cacgtttgta
    43081 ccgacgttgc cataacactt caaagtctgc tgttaggcga atcgtgatca cctgatatcc
    43141 gtatctatct gctaattctt ggagtcgtgc tttttgctta tcactaaaag gatactcgga
    43201 cacaatcact ttctttcctg cttccatata caaatcaagt gctttgtaat agaaaggata
    43261 aactttcgtc ctttcttgtt ccgcccgttc ttccaaattg ttaaacccga tggattctgc
    43321 atagtattcc ttgatttcat cgagcgtgat ggcatacata tctggaaatc gttcccgtag
    43381 tttattcata agatatgttt ttcctgtacc aggactacca gccagaagaa tgaaatactt
    43441 tttcatctca tttatttcct aagttaattg gactttccaa gttcataaac agtccaatct
    43501 tatgcttgac aatttctttt actgcttcat ttgctggaat cacattatgg cgaagagact
    43561 tgttgatttc tgtttcacta aaggtttctt tagctacttt cgtccagttg actaaaagct
    43621 ccgttccaac attgaatttg cggatcccgt tattgatcaa ttcaggataa tcttcttctt
    43681 tcacacctgt tcctccatgg ataactaggg ggacatcaac tactgcatcg atttctttca
    43741 gcaagggaat gtttacttct gtttttgatt tgaattgtcc atgattcgta ccgatagcaa
    43801 tagctaatgc atccacgcct gtagcttcta caaatttcac tgcgtcttcc ggtcttgtat
    43861 ataccttgtc attttcagcg acatggattc cttcttctgt accgccgatt gttccaagtt
    43921 ctccttctac ggaaacaccg tgcgcatggg catattctac tactgctttt gtcttcagga
    43981 tattttcttt gaaaggcaga tgggacccat catacatgac agaagtatat ccgctgtcga
    44041 ttgcttcttt gatatcatca aagtctcggg cgtggtctaa gtgcaagact gcatcaacca
    44101 tttcttcttc tgcaatagct gtcattacat tgactaacac atgcatgccg atatatttag
    44161 cggtatcgac acttgtttga ataatgatcg gcgaacccat ttcttttgct gcgcctagca
    44221 tagcaggaag catttctagg ttatgcgtat taaaagctcc aactgtaaaa ttcaactctt
    44281 ctgctgtttt tgttacttct ttcaatgttg tatacatctt ttattgccac cttatctttt
    44341 tatttgtttc ctttgatcgt tacttgtttt gcaatttgtc gcatctcatc cattttgccc
    44401 atgtagtaat cgatcccttg atcatcacca gcacgagcag catctgcacg cttctggtta
    44461 tagaggctca tcagtttttt atacccatct ccgatcgtct gtttattttc caaactcttt
    44521 tctaaatatt ggatggcttg atcgttcaca tacaattcag aaaatttaag tccaacttgt
    44581 tcataaagtt tcgctaattt atgcttatct tgggtagtgg aaatctcttg tttcaattgt
    44641 gtaatctctg attgaatctt ttcggtcgct tctggcgata gggctttttc ttcttttgcc
    44701 agaacttttt tcggttcttt ttcttttttc ttaaaaaatc caaacatcat tttccctact
    44761 ttcaattaaa atgctttcaa aactgggctt aagatccagg catataagag tgctgcggct
    44821 actgtatcta catcggttgc tgtagcattg ttgaatccca tcgaattaaa gatcgttact
    44881 agcaaagcgg gcaataatgt aataaagaaa ccatgagcaa taccgccaat gatcgctcct
    44941 cggcgtccgc caactgcgtt gccaaatatc cctgctgtcc ctccggcaaa gaaattggtt
    45001 agcataccag gtaaaatcat cgctaagccg aacatgggca aagtaaacat ggcaataatc
    45061 gtaccaatcg ttgtcgtaat gaaacctaaa atgacagcat ttgggctata aggaaagaaa
    45121 actggacaat ctaaggcagg gatcgcatca ggaactaatt tcatagctat ccctcgaaat
    45181 gccggcacga tttcacctaa cagtagacgt acaccagcta gcaatacata cacacccact
    45241 acgaattgga tggcttgtaa aaaggcaaac atgatatagt tttgatctcc tgataattca
    45301 gaagcgaatg gttcgcctgc aaataaaaca gtgatgatat atagcgggac catcacgacc
    45361 atgacagaca aataagtatc ttgcagaaat tcgaaatgtg tcggcaactt gatatcttcg
    45421 atcgactttt tattttcgcc tttctcacca aaaagcttag caacaccggc ttcaaataag
    45481 tacccgatcg tacaaaaatg acctaaagca atatcatttg atccagtgat tttacgaatg
    45541 atcggttgcg ctactgccgg catagcaatg gcgaaacaag ctccgataaa accaccgacc
    45601 aagatcaata cgatccctcg cagaccggca aaatagccaa agactgtcgt catcgttgcc
    45661 atccataaaa ttgcttgacc agttaaaaaa atgtacttcc attttgtgaa acgagccaaa
    45721 ataatattga atacaaaaat ggctaagaac gtcagtgcaa tatctctacc taaacccaaa
    45781 tcattcattg cttgaccatt gatagattca atagaaggga tgatcccttg catatgaaat
    45841 ccttcagtaa agattttccc gaaataagtt aaacttccaa cgatgatgct cgaaccggca
    45901 ctcaacactt gaaatcctag gagtgtcttt aacgtgccag agatgacttg tcctgctgat
    45961 ttcttctgca gtagtagacc caacatagca atcaatgcaa tggtgatcga tgcctgagtc
    46021 aaaatatttt cgatgataaa attgataacg cccatgtttt taccctcttt tctttttgta
    46081 tttagataac tcccttatct tgcagaactg gggtgatttt ttcttcaatt tcattttttg
    46141 aaacaatatt tttcaaatag atcatcgccg ttttaggatc aactgcgaac ttttcgaact
    46201 gcgaacgaaa attttctgct gtgatgatca catctggttt catggaaact gcggaagaaa
    46261 tatcacaatg gtccagtttg gcttctactc ctaatttgtt caaaacatcc tcagcagaca
    46321 tctgtgctgc aaaactactt cctaaacctg caccgcatac gaataaaatg ttcaatttgt
    46381 tcatctttgt tctcccccgt atcatttatt atttctcaac tactgaaaaa agcagttgtt
    46441 tgaaatcttc gatatttgtg cattcaatca atcgatccaa cttctcttcg ttgttgatca
    46501 attcaattag ttctttcatg atgttcagat gcgagtagga gtctactgct gccaaacaaa
    46561 aaataatctt tactggatcc atttcaggat taccgaaatc gattggttgc tcaatcgtag
    46621 ctacgctgac tcctaattta ttgaccccat cttctggtcg ggcatgggct agtgccatgt
    46681 gtttgccaat cacgatatac ggtccgtaat cattcactgc acgaatcatc gcttcgacat
    46741 agcgctcttc gacaatgttt tctttaacca atggtctagc agctagttca atcgattcct
    46801 cccaagtagt ggctttttct ttgatcatga tattgctgtc cgtcaaaata tcttttaaca
    46861 taggctggat ctcccttttg ttgatttcta aattgtttgt ttcgaataat ttttctaact
    46921 tgccatagat gattcgatct actcggccac cactttcttt catgacatct attatttgag
    46981 tgaataactc cgtcgattca tgactgttag gctctaaccg ctgtagttct tcatttcttt
    47041 tcaaaaagtc ttctataacc aagatattcg tctcagttaa aatcggatcg acaactaaaa
    47101 gcggcttatt tcgataattc aattgaaagg tgctgaaaac cagattgaca tccaatttat
    47161 ctactaattc gatttctttt gaacttaaaa ctgcagtaat ctcgatctga ggaaactttt
    47221 ctttcagatt ctctgctaac agatttccag tagccatccc atggttacag acaacgactg
    47281 atttataaac ataattcaag tctcgcttga ttacactggc gatcgtcgaa aagtggatga
    47341 caagaaaagc tatctcgtcc tccagtatct tgccaccaat tacttcttcg atcgtaggaa
    47401 caaaatgagt gactgcgcgg tagattggga aataatttgt tcggatgttt tctttcaatg
    47461 gattcatgac ttggatatga ttcttgattc ttacaatcag tgcagccatg tgcttataga
    47521 gattttcgaa taaagcttct tcctttagat ggaaaggtac gtgtgtctcg ttctctacaa
    47581 attggatcaa ttggatcgtt agtaattgag cttgtaccca ctcgattgaa ttggagatat
    47641 ctctagcatt gaacgtctca atagtgaaac gaagataatt tctttctact tgcgggacat
    47701 tgtccaattg aaattcctcg atcatgtggt caataaatgc agaaaagcta ctgtctttta
    47761 tttctgtatt tttccaatta atggcagaga taaattcatg tttcctgatt cgctggatcc
    47821 agatcaatgt aaaaagcagg atttgttttt tataaatatc atcttcttgt ttcaacaact
    47881 tattggaata gatctcctgt atttttttga tttccaccaa aggaaaataa tggagaaaga
    47941 ttttttgagc cggtgttaat tgtgcatctt gattcataaa gaagtcggtc attcccagat
    48001 tctgattgat aaaatcatag atcatcgtac ggatagatcg ttctgaacct ttataaacca
    48061 gtccttgctt tccataactg acgatctcta tcccataact gaccagtgtt gctcgtaacc
    48121 gtctcatatc ttcatctaat gtacttttag agatttgaaa ttcttcttct tttttgttta
    48181 gatggatcgg gattcggctg taagcaacgg ctaaaactag atcaaaaata cgttcgcgcc
    48241 gattcaaaaa gccgtctttc acatctttta tttcagtttc taatcgagct tgcttttcct
    48301 tttccagctt caacaaaaaa cctttgttgc gaattgtacg gatctccgga agctttttac
    48361 tgctcaacca gatattcgct tcaagaactt cctgacggat cgtccgctga ctgacattga
    48421 actcacttgc tagatgtttt gcttttactg gatattgggc tgtcatgatt ctgtgaagta
    48481 tttcaattgt tcttgttttc atagaaatga tctccttctg atttcaagta tatggttccg
    48541 cttacataat aaaaagtaga tatttctgcc acttgaagtg gaaagaaagt aagcaaagca
    48601 aacaaaaaat aagccatatg ctttttcatc tcctcaacga aaaagacata cgcctattat
    48661 tacaaaaatt ttgcccatct atacaaaaaa gaggttgtga aaaagctgtc ctgcatcaag
    48721 taataagaac aactaaacta aaatagtgct tcctattttt cgtttggttg ttcttattat
    48781 cgcagatgca agcttttaaa caccatttag tggagaggtt gtgacagaga tgttcagcct
    48841 tgagcgataa gaagcgattt tgaaaaatcg cttcccatat tttacaaaat cgtgccttat
    48901 tgccgatagg ctatctctgg cacaccgttt attcagaaaa aggagctgcg acaaggcttt
    48961 tgtcacaact ccgttcataa atatttcctg tcaatccagc ataatcggct gaataaaatc
    49021 ggcttgccat cttttttctt tctcagaaaa atcaaaatac catatctgag aaaaatactg
    49081 tcgttgtgtc ttacttcctg agatcaatcg cccatctttt cgatcgactg aataatcaca
    49141 gcatctgaaa tcaattcgga tggcaaaact attttcgtgg atctgtcgat aatttcctac
    49201 ttcctgaata gttatttttt tagtatgatt tcttacaccg tctgctttgt ttttttgcag
    49261 aactttctga tgttcggcaa acagcttgtc tgtataacag cttctggctt tttcaggagt
    49321 ttcttcttcc caagcggatt ggatcttcat gaatatcttt tggatttcca gaaactgtgc
    49381 tttcttttct ttagccgttc ctgacatgcg ggacaatatc tccgctttca gccttttctt
    49441 ttgtctttta ttcttgacga tagaaaaagc agaaacccct cctactgaca aaacagctaa
    49501 tgcaagaaat cccgtttgct cataactaga aggacctgta cctggaccat aatacccata
    49561 agaatctctg ccgtaagaac gactgccaaa ataactgccc ccatatgaac gaccaccaaa
    49621 tgaacctctg cccgaacttc gaccgctaga tgtacctcca ccatgaccac ccgcgacagc
    49681 gaatccttgg gtcggcagag caaacaaaca taggcccact aacaaaatga ttgctaaata
    49741 attgattttt ttcattgtct tcctcgttat cttttattac aaaaaactat ttttatgata
    49801 gccttgctaa aaggaagagt caataaccag atgcataaac tgttttttta gcaattttgt
    49861 cttatttagt cattgagtaa catcggacaa atgtatgtgt cggcagtcca taattcctct
    49921 atcttcagca tgaacaagct tgcagacaag agatctgcgc ttcctccagg agagatttgg
    49981 ttttcctgac aaaagtgcaa cagtgctgta aatggacgat ttggtaaagc actttgacta
    50041 gcagcatgag caagtttttg catttccact aacgttttct gatcactgcg atgcaatacg
    50101 catgtgtcat ctagcgaact catcaaaact aacaacatat gcatttgttt ctgtacatat
    50161 gaatcattat ctagctcctt agctgcttga attgcaagcc tgatatgcgg ataccctaat
    50221 atcgcttctt catatgcacc atttacgcca tatttttgct tcaccctatg accatgagtg
    50281 gtttttttat gacgatattt tgtatcagga aaagcagcaa gcttgctgac atcatcaagt
    50341 attttcgata aagaaaaagg ctgttccata ctgatttttt gtgcaatgac actgatcaat
    50401 agccccattg cccaaatcgc tcctttatgg gtattgatgc catttgtagc aatcagcatt
    50461 gccttttccg cttttcgccc aatctcagca attctttctc ttaactcctg atcaatagca
    50521 tgatgccatg ctatttgagc catttcttca aaaaaaggag ttagcgtctt agcagactta
    50581 agaaataaag catagtccat atcggaatgt gcacccgcat ccagtgcatc cactaatcca
    50641 ggttttggac ttaatgttac ttctgcgatc aatgcttcct ctaccaacgc agcgagttgc
    50701 tgagtcactg ctttttttcg ttcgtcattt atcatgacac tcactccttc ttcctactat
    50761 tacttgctga aacctttttt gatagctacc caaatgatat gaagtaacca gcttaaagca
    50821 aatgcacaac ttgccgtcat tagataagct acaagaatca tgactcctga aggtaactgc
    50881 agccaactat ctttaaacaa taataacagt acttggaaaa caaatacatt ggctaaatac
    50941 gtacgataag cataaacaga caaccatttg aacaatggca attttggcga atcgtttaca
    51001 atcattttgg aagcgcctat gaagacagca aagatgatga ctaaactgta taaactttgg
    51061 atcgtattca agtaaggtgc attcgcaaag ctcaagtctc ctggatgtgc gagcaatgaa
    51121 cggacagaaa agaacgcgat aactaaggca acaggtaaga aaagataacg tactctgtcc
    51181 aaatattgat agactttttc gtgataaaca aatgcggcta ccccataaat catgaaacta
    51241 gcaacaaacc gatctaataa gtaccagctg tcatgataag gcccagtcaa tacttgtgtt
    51301 tgatagaaca gataccatgc gacatataaa atcgttgaac caatcaatac tggccataca
    51361 tattttttat tagcaaatac tttgtaaccg agccaaacaa aaaacggcat gaacaattgg
    51421 atctgcagca tcataacggt ataccataaa tgaggcgctc catcacctgt gacatatttc
    51481 agtaaaaagc ttgcagtatc cgtatacgga gtttgttgtt ggactgctgg aaatagccaa
    51541 agataagccg tcgtccatag aagatacgga acgactagtt caaaaaactt ttctttcaaa
    51601 aattcccaat aagacaaatg ctgacttgtt tttaccatat tataaacaat tgcaaaaata
    51661 aacattggtg ctgtgtattt aacgatgacg taaaaggtac caagaaaagc tgtatttgtt
    51721 gcgctgtggc tgtttgccaa agcaaagctc aatatcgttt gcatcataac agccgttaca
    51781 gctgatactt tctggaagtc acttacgttg attttgattt ttttgttttc aaacatctct
    51841 ttctctctct ttttctttat taccaaagtt ctttggttaa tttaggtcct tcgactgttt
    51901 tcaatagaat ttttttctct ggctctctca aatactcttt tagtgaaaaa ccgccttgcc
    51961 gagtcactac ttgggtatcg aattgctcaa aaaaagcagg atgcgattga attacctgaa
    52021 ttggcaattc aatcggtgaa tttgcgtaca gcagcaaatc aaaatcactg gtttctttta
    52081 ctgccggaat cccagtcgat aattcaaatc ctaagctgcc gccgattccc catttacatc
    52141 ctgataatat gtttctagca gcatgaaatt gctgataaac aggataatcc atgattttct
    52201 cttgtctata cgattcttgt tcgatgatgt cccacggatg aatgacttgt ttgacggcat
    52261 gttttgagat ttctgttgac catctctgat tgcgggcagg tccacgtaaa ccaatcggta
    52321 gtatttctgc gtgatccgtc gacgcacgac gaactgttcc gaacatcttt tcagttagaa
    52381 cgacccattc aggcaaggtg aacccttcta tttcatgttt atcaaaaagg acaatatcat
    52441 gtgcttgaat cattttttat gcatcccatt cttcgtccat tttggcacgg actttatttg
    52501 tttcgacacg tccgaatgtt ttggctgttt cgtttgtgta tcgatttgtc agcatcgtgt
    52561 catttgtatt gcggacatct tgaatggctt cattgattgc ttcgatgact ttgctgacat
    52621 tttgttctga agcagcttgg tcggtgatat cttctaggaa atgatagatc gctcctagtt
    52681 ttgtataatt attgatatcg taagcgatag ctggaacttt ttcagcagct gcttcgattt
    52741 cagcaaccga acgttttgtc acacgtgcag cactttcttt agacatcgct tggacggtaa
    52801 tttctttatt gtttaaagca atcaagcggc ttgattgtaa tccatgtgct aaaaatgcac
    52861 ctgaaatagc atttcctgca atcaatccaa taactggatg tccagcttga cggagttttg
    52921 cataagcagc agcactatta gccaaagcca catggatacc gatcaattct tcgttatagc
    52981 cgtatgcttg gcttggtaca tcgatcacaa cgatgattgg ccgtttcact tttttgtctt
    53041 tatcttcttc gtaaacgtga tccaaaattt gtcccatgcg gaaaccttca actaaaccaa
    53101 cttcaccgtt tcgtacacgg tacatcgggt ttttaggatc aggtacgatt gatgtcacga
    53161 tggcttcttc tatgaattta cttgatttac cataatacac agtactaata gaagaagttg
    53221 gatttttcat gccagttagt gccgcaaacc aatcgtaacc aacacttgct gcagctggtt
    53281 catttccttc tgctacttct ggtaagtcaa ttgattttgc ttgatggtta gcaattgctt
    53341 cattgtaatc gtcaatggcc attggttttg aaagatctaa agaatcaagt aatgataaat
    53401 aaaatgctga gctttcactg cgatgcgtgt cttttcgttc gtccattgct gcgatgacag
    53461 cagctttgat tgcttctaca ctatcagtca ctaattcatc aatgattttt gattctaccc
    53521 gttgacgaga tcctaatgta ttccaaatca agtctttgtc actagaatca aattctcgaa
    53581 cgcctgcttc ttgttcaata acttctggtc cattcaaacc gactctcgct ttttttgttg
    53641 cgattaaata actcattaat gctgaagtaa tcgacatacc gccaaatgat cctacacgtc
    53701 ctggaatcaa accgatgact ggtacatatt gttttagagc aatgattaca tttccgattt
    53761 ctgaaataga taacagtccg tagtttgctt cttgcaaacg aacaccacct gtatctagta
    53821 caatgactgg aaagatctca tttccttttt tattttcttc taacacatgt tcaagtgcag
    53881 caacgatttt tgcaccggaa acttcaccga taccgccacc ttggaatttt ccttccatag
    53941 cgattactac tgcttgtttg ccattgatcg tgccacggct gacaacgatc ccgtcatcac
    54001 tttcagggac gattccttgt gctggtaaac ttggcgcgat gatttgatcg aatggatcaa
    54061 tcaattcacg tccattgtca agtagagcgt tcactcgttc tctggcgttt aattctacaa
    54121 aactattttt catctgaaag ttcctccatt gcttgcgtca atcgtaggta cacaactcct
    54181 ggtgtagcac cgaagtcatt gatcacgata tctgctgaaa ttggataacg atcaaaaaat
    54241 ctcgttaata cattgttcca tacttcgccg aagccatcgc ttcctgtaca aatttttaca
    54301 gtagattctg ttttttctgt tggaaacatc aagatttcca aatctcctga accgaccact
    54361 cctacatgga ttttcttatt gatcggctgt ttcgttggat atttataagc taattgttcc
    54421 atggatctct cccctttttg taaaacagag catacacgtt ctgcttattc gtctttcttc
    54481 ttccatctgg gtaaatggcg acaaaaggtt tttctcgcca attttatgac caagttctga
    54541 atttcattgg tggttcatac aggccatctg accattcgat caaatcatcg atggtttgtg
    54601 cagctaataa tgaacgtttc gcttcactac gtttgatgcc tagatcttct ggtaatttca
    54661 cgatgccggc tgcacgcaag ctatctagtg attctttcgt gctagtcatt ccaagaggtg
    54721 taacaccgcc aattgctgca attgctgctt gtcgttcttc ttttgttttt gctttgtaca
    54781 aataagcaat tccttcttct gtcacgatat gtgtagtatc ttcgctataa atcatcactg
    54841 gtgcattggc taagcctgct tgtttttgaa cagctagtgc atctaattct tcgacaaaga
    54901 ctggtttttt atttgaacca tatgtttcaa ccatttgaac aactaatttt tggcctttcc
    54961 ctaatggatc atcattgtcg cgaagtgatt gccatgctgg tgtagaatga cgacgaccgc
    55021 caggattatg tcccatgtta ggcgcaccgc caaaaccaga taaacgtcct tttgttacgg
    55081 tagaagagtt tccttcgtaa tctaattgca aggttgaacc gataaacata tcgatggcat
    55141 attgtcctgc agcttgtgat aatgttcggt tactgcgcat cgtgccgtct ttaccgacaa
    55201 aaaagacatc tgggcgagca gcaatatatt tttccatacc aacttcgcca ccaaaactat
    55261 ggatgctttc aacccaacct gattcgatgg ctggaatcat cgttggatgt gggttcaata
    55321 cccagttctt cgcgattttc ccttttaacc ctagtgattc accataagtt ggcagtaaca
    55381 attcgatagc tgctgtattg aatccaatac cgtgattcaa agattgtacg ccgtgttctg
    55441 cgtagattcc tttgattgcc atcattgcca ttagaatttg caattctgtg atgttttgag
    55501 gatctcgtgt gaataaagct tctaattgat aaggtttatc tgctttcacg acaacgtcta
    55561 cccagtcacc agggatatct acacgtggta aagaatcgac aacttcgtta acttgaacga
    55621 tcacgatacc atctttgaaa gctgcagctt cgatgattgt tggtgtttct tccgtattga
    55681 aacctgtgta caagttgccg tctttatctg ctttatctgc agctactaaa acaacatttg
    55741 gaatcaaatc gatgaataag cgtccataaa gttccaaata agtatggata tcacctaatt
    55801 tcattgtgcc gtcttcaatc atttgggcga cacgcaagct ttgtgcacca gcataagaga
    55861 aatcgatctt gcttgcgatt cctttttcaa aaatattcaa atgttctggt cgtgagatac
    55921 tagacatgat caaatgcaga tcattcactt tttctgcatc tactttttca agactttctg
    55981 aaagaaaact tgcttgtttt tgattgtcgc cttctaatac aactttgtcg ccgggagcaa
    56041 tcagtttttc cattacttct acgatttttt cagtttctac atacttgcca ttgagcaagt
    56101 tgctgatttt ttccaatcgc tgcgcttttt tttcgcgttt agaagcccag ttgcggtttg
    56161 gtttttccat aattagtcat ctccattttt gatatagaaa cgtggcgtca tcaataccat
    56221 gttggtctag attgatcgta cggatccctt tatctacacc aaattttgta tgaatcagct
    56281 ttgtcaaagt attgccgggg ggaaattcaa tcgtcagatc cattcctaat tcttttgcca
    56341 agtccatcat ttggttccac tgcacaggga aagctaggtt ttccaacaaa tctttacgaa
    56401 tctcttctgc gtcctgagtg gctcttccat ccgtattttt tatatacaaa catctagcat
    56461 cagatagatg gacagactgc atatacggct tgaatttctt gaccgtatca ttcatcaaga
    56521 gacagtgaga tggcacaggg actttcagca gcttcgctgt ttgcgcttgg tgccgtttgg
    56581 cttctgccaa cgtaacggat aaaccttcga tactcccaga taacgtatgt tgcatcggac
    56641 aattttcatt tgacagataa actggatggt caggatcaaa tgtttttgct acaatttcct
    56701 cagcttcgct tctcgtcaca cctactacta cgcccattgc ataaccgctt ggataagctt
    56761 ctttcattaa gactgcgcgg tgatagacta gttccgctgc attctcaaat ctcaaagatc
    56821 gacaagcaac agctgcacaa aaagcaccaa tcgaatgtcc tgctgcaata tcaggctgaa
    56881 taccgttttt ttccatttca tctaaataaa atactgcttt tgtcagtaat gctagctgga
    56941 taaaaaccgt atcttgatag ttttcttctt tatcaactaa ccgatacccc gtcacatttt
    57001 ctaaacgttc catgtacatt tcagggatat ccgctaacat ccctaacttc tgactgcctt
    57061 gtccaggaaa taagaaacct gtactcatga gcctcgcctc ctcagcactt actttttcca
    57121 ctgctatctt agtcaatttc tgctataata aaaaatgcca aaaaaagaaa aaaccataac
    57181 aaaaaggtat ggatgggatg gataattatg aaattgcttc atctgcagta ttttaaaaaa
    57241 gtattcgaaa caaaaaatgt tacccaagca gccaaagaat tatttatttc tcaacctgcc
    57301 ttgagccgtg cgatcaaaca tttggaaaac gaattaggtg tccctttgtt ttaccatagc
    57361 ggcagaaaca ttgagacgac cgtttatgca gaagaatttt atccatatgc agtcaagaca
    57421 ttagacacat tagaagaagg aatcaaatta ttgtcttcgg tcaatgagaa gatcgttact
    57481 tccgtcatat tgtatttaga ggtagcctct gtttctattc cgaacttggt ccgaattttt
    57541 atggaaaagc atcctgatat ccaattaacg atcatgcaac atcatttacc agatgatatt
    57601 accgatcctg tactgtacat cacttcggag atgaagcctg gcatgaccaa tattcctatc
    57661 atgaaagaac ctgtttatgt cgccattcct aagaaacatc ctcttgctaa aaaagaacat
    57721 ctgcaattag aagatatcca acgcaccccc atcttgatgc tgtcaaagag caacgccttc
    57781 cgtcatacac tggatgcagc acttgaagcg aaaagtatcg aattgacgat cagttcgacg
    57841 acagatgatc ctgcgacatt acgttctatt gtcaagcaag gattagctgt tagctttttc
    57901 ccaaaagttt cttggtctta cgataaaaat gatcctttcg tcttgcggga aatcaaagat
    57961 ttgcccttga cacgaacaat ttatttatct tctagcttca cagaagatca tcctttgatc
    58021 aaaatgattg caaaaacgat gcgggaattt tatttaggaa aataaaaaaa aaagagctgg
    58081 gacaaaattc ttgtcgcagc tcttttttcg aacaaacggt gttccagaag taatttctta
    58141 gaaaataagc cgaaatttcc caaaaatttg agaagcaatt ttcgtaaatt ccttcttatt
    58201 tcttgaagct aaacatttct gtcacaacct cttctctatt gtcctagaca ttcattgcgt
    58261 tgatttaaaa cttccatcaa tcaaatctgc tagttcatct agcttttcta ttttacgtag
    58321 atcaatagag atccaatgtt ctttattcat gtgataggct ggaaaatacc cctcttttcc
    58381 tcgcaaaatt ccgccaagtt caggatcgac cttcaaatca agaatattga tgatcctatg
    58441 gtcacttgca tcatcataga ttttttcttc tggaacagac atcaggaccc caaaccattt
    58501 tttgcttttt tgatgtctga atacgcaata atcaggaaat tttttaaaaa tatattctgg
    58561 agacaaattg tatgtttcat tgatgtgatc gattagttct tttttcgtta gcatctgctt
    58621 ccatctcttt cttattgatt cgctttattc aaagatacca cgtaagaata gaaaaatgaa
    58681 tacaagtagt tgctaatcaa atacttcgat atttttcttt tttatcaact cttaaatgtt
    58741 caatccgcct gtgttggtct tgctaccatc tactattaaa atgtttatta ttgtttgccc
    58801 acctattttt tgattttagt ggtatcattt ttcaagttca tgatgaaatt cttatcatca
    58861 gtaaatgctc cagaaaaata aacaatgatt gaaaaatcag ttgaaacttg accaccgttt
    58921 attttctccg tattcttaga atagaaggga gtctgattga tgtattcact aatgaaaaaa
    58981 atcattaccg aaaaagatat tcgacgtcat gtttctttag tagaacaatt gctgaatcat
    59041 acaaagataa ccgtaaatga attagctgaa atcataggga caaccgaacg aacgattttt
    59101 tctgaccttc aatctattcg ctctcagctg cccgaaggct gggacatcat cagcgatcaa
    59161 gcaggaatca gtttgcaaaa ccagcaaaat ttattaacaa atgacctttg ggagattttt
    59221 ttcaaacaat cagtcagtgt cgaactgctg aaaaatctgc tttttacaaa aaaagttgct
    59281 gtccctgatt ttctagccga ccatgggctt tcttatggga cattgaaaag acatgtgact
    59341 aaaatcaatc agcgtttagc aagttacgac ttgcagatcg atttgacgaa atatacagct
    59401 tgtattcttg gaaaagagcg tgcgattcgt actttttatc atcgattgct gattcctttc
    59461 actcataaca actatttttt cgaggattat tcgatccatg aatcccatta ttttcaattt
    59521 ttaagaaacc tcagtcaaac tgaactagcg gttgaaacag aagagatttt cggaacatgt
    59581 tggttcttta tcaatacgat ccgtataaaa gcgaattgcc gattagattc ttctatccat
    59641 accaacagca cactctcctc cctgtatgac tctgcattga aaaaattgta tttaacggaa
    59701 ggtatttatc ttaaagacac tgagctttct tttgcttctt tctgctttct ggaaagttgg
    59761 aattacaaca ataactatgg acaagaaacc gctcgctgcc tgcatcattc tccattttta
    59821 gaggtcctcg aaacgtttgt agaggaacta gcttcagagc tgtctcttga tcaactaaaa
    59881 aaaacatctc tgactgataa cttggctctc ctcatattaa aatatcatga atcgccgata
    59941 ttgattgaag cattggaccg tcaataccat cgttttttag aaacatatga tcagcaatat
    60001 gcacacttgt atcaacagaa agagaattta ctgaacgatc taaaaaaaga aatagaaatc
    60061 aatgaaccaa attactttct ccaactcttg tctctactga tccaacaaac gattttttct
    60121 atcaaaccga atttgttcaa tgtctatttt attttccaag gagaaccttc atggaaggcg
    60181 ttcttgcagc aggaattaaa agattactta ggaaaacgtg tctgcttctt acctatcgaa
    60241 ctaaccgatc tttccactat ttcttttgaa aaaacagata tcttgatttc caatttccct
    60301 ctagattctc tagatatccc tattgtatac atttcttcta ttccaacgaa aaatgagctc
    60361 aatcgtttga ctgaactcac tttcaaaact tttttatagt aacggctagc gactgtattc
    60421 tctagctgtt ttttcttttt tgcgaaacag tttgttcatg atcccttttt ctatttctac
    60481 aactaagaat agaagaatca catttgctcc aatcaataac tgttgtgtca tcgttaaact
    60541 tactgtaccg atcagctgct ggccgactgg tagaaaaata accatccctt gcaataaagc
    60601 aaggatacct aatgaaagaa aaagcgcttt gttttgcaaa agaccttggt tcaatgacgg
    60661 cttggacaac tctctgcaat tgatcatgta aacagcttga gctaagacga tattttgcag
    60721 aagaatggtt tgctgtaagc tttgcccttc aaactgcata gccaataaat aggcaggaac
    60781 catgatcagt agggagacat agatgatccg aaacaaatga taaccagata ggattccttg
    60841 ctttggatct cttggtgggc gcttcatgat ttctggatct ggcgactcga accctagtgc
    60901 ataagataaa gtgattgtcg ttaccatatt gacccataaa atctgtactg gggacaaagg
    60961 tagcgggcga ttcagcataa gtgcccaaat caagatcaat ccttgagcta atgcagttgg
    61021 caagaagaaa ttgatggttt tttgcaaatt atccaaaatc cgccggccct cttttacggc
    61081 ttttgcaatc gtatggaaat tatcatctcc taaaaccata tcagctgcct gtttgcttac
    61141 ttcactacct ttgattccca tagcaattcc tacatcggat cttttcaaag caggtgcatc
    61201 atttacgccg tctccggtca ttccgacgat ttctccattt ttctgcaaag ctttaacaat
    61261 tcgcagttta tgttctggtg tcgttcgagc aaagacatcg actattggca cttgctgaat
    61321 caactcttca tcagacataa gatccaaatc gatcccttct aaaactttgg cagtatgttt
    61381 taagccaatt tgttccgcaa tcgcttttgc tgtgtctttg tgatcccctg taatcatttt
    61441 cactgagatc cctgcttgtt ggcattcctt tacagctttg actgcacttt cttttggcgg
    61501 atcgatcaat ccggcgatcc ctgcaaaagt taattgggtt aaagtctcat gcgtgagttc
    61561 ctgtttcgaa tctacttttt tataagcaaa tcctaaaaca cgctgacctt ttctcgcaaa
    61621 ttctgcagct gtctgactcc atgcttcttg ttctgcagaa gaaagagttg atttagcaaa
    61681 taatacttct ggtgcacctt tgacgtaaat caccgctcct ttttcctccg catgcatcgt
    61741 tgccatatat ttgtattcag aactgaacgg aatctttgct tctatttttt tcaaaggtag
    61801 attggctgtt tctgtgtgtc gaatcagcgc aacttctgtc ggattgccac ttaaattttc
    61861 tgttttctgt tcttcttttg tttttaattc ctgacagttt ttcataatgg acaacacgca
    61921 ggcttcttct tttgcagcta catccacaac tgtcatttca ttttttgtca atgttcctgt
    61981 cttatctgaa cagatcactg tcatagaacc taatgtttct accgaaggaa gtcctttgat
    62041 gatcgccttt tcttttgcca tttcatgtac tccaacggat agaatcatgg tcaaaacagc
    62101 tggcaatcct tcgggtacca ttgacaccac caaagcaatc gtagccgaaa gaagaatatg
    62161 ccaatccata ccatatcgaa atgtcgtaaa aataactaag aataggctca aacaaagaat
    62221 gccttgaaaa atttgtttgt ttaatcggtt gattttttta atcagaggcg tcgtttgttg
    62281 ttcgaccgat tgcaatgctt gattgatttt accgatttct gtcgtgtttc ctgtttctac
    62341 aacgacaccg actgcagaac cagattgtac aagcgttcct gaaaaaccca tatttttctg
    62401 gtcgccgatc gattcttctt ctgtcaaaac ggcatgactt ttttcagatg cttctgattc
    62461 tcccgtcaaa atcgattctt ccactaataa atcatgtgct tcgattaatc ggatatctgc
    62521 tggaacgaca tctccggcac gtaagacaat gacatctcct tttaccagtt ctttcgcagg
    62581 gattttttct tgcatcccgt ttgatagtac tatcgcttct tgtcccatca gctgcttcaa
    62641 accattcaat gattcttccg cttttctttc ttgccagtaa ctaacgagtc cattgacgat
    62701 cactacgaat aaaataatac ttccttcaat atattcacta gaagcaaatt tcaaaaaaga
    62761 ggcaatgatc aacacgatca tcagcagatc agtaaaatgc tttgctattt ttttccatcg
    62821 ttttgtctgc tgccttgctt ttatttcatt atatccttga tcagtcaggc gtttctgtcg
    62881 ttcttcttgc gacaagcctt ctgttgatgt ttgatagttt ttcaatacat cttctaccgt
    62941 caatctgtac cagttcatcc tatcccctcc tgtttaattg atactgttat tatacgcagg
    63001 gaagtttttt caggcgtatc gattatttca ggggggtctg aaataattcg ttttgcaaaa
    63061 tgtatctggg cctaactgat atttctattg cttattcttt tatatacaaa atttaagaat
    63121 acaaaccaga taaccaataa aaaaggaata aagcgtgtcg tgctttcgaa taacaagctg
    63181 aaagcaattg aagtaaaaaa caccaacaaa gcaagatctt tatatctttg tgtagtgttc
    63241 cgtttctttt ctttaataaa ttgaacatgt gcacacaaga tcgaagacca cacaaataga
    63301 aaacaactcg ttgtcatgcc tgccaaaagc tgaaaaaaca atcgactatc agctacaaaa
    63361 aaatgtagac aaagaccggc aaaaaataac attcctgtaa ttaaaatacc gtgtaaaggt
    63421 acgcctttct tagaaagcgc acaaaaccaa tggggcaaac ttttttcttt tgctgtttga
    63481 tataaaatcc tgctagtact gtagactgca ctatttgctg aggacaaaga agcaaccaaa
    63541 atcattagat tgacaattgc tgctccgcct tggcaatgga tcacttgcag catagtcact
    63601 aaaggacttt cttttaaatc taaacaatgc catggaacaa caaataaaat cgacaaaatc
    63661 gttcctatat agaaaaagag aatacgccaa ggcagacagt tgattgcttt tttcaaattc
    63721 ttttgcggat cacttgtctc gccaacggtt aagccgatca tttcaattcc agcaaaactg
    63781 aataaaacca taggaaatga gactaccatt ccagcaaagc caaacggtag taattcatcg
    63841 atctgtccaa aattttcttt gattccgata gactgggtat gaaaatctga gacactcaat
    63901 cctataccca ataagataaa aaggaaaatc cccaagatct tgatgattga gaaaaaagat
    63961 tccaattcac caaaccactt gactgcaaca aggttgactg ccattaagat cattagtgcg
    64021 ctacctccgc ttatcaaagc tggtacatgt acaaaccaga aatggatata caatcctatt
    64081 gctgttaatt ccgcaagtcc agctccaagc cagcaaagcc aataagtcca attgacaaaa
    64141 aatgcccact ttttgcctaa ataatagtca acgaaatcac tgatagagtt aaatgtacta
    64201 tttgctaaaa ataaatcacc catggcccgc atcaaaccat aaatagccaa accgcatatc
    64261 aaataaacga gaataacagc tggccctgct gatgcaattg cctttgctga acctaaaaat
    64321 aatcctgttc caattgcgcc acctaatgcg attaactgga tatttcgatt agttagagtc
    64381 cgtttcattg ccggtttttc catcaagttc acctttttct ttttcaagca gcatggcgac
    64441 ttcctgttcc caagaaggtt tctttatttt ttcaatacag agtggtacta caaacaaaat
    64501 gacactgatg gctgtgactg caattagatt gatccatgtt ccagctttca tcgtcagtcc
    64561 gacagaaaat ccgattgccg caaataaaac aataacgaca gtccaaactc caagattgct
    64621 ctttttctct ttttttccaa ttctaaatgg tcgattcaac tttgcatgtg tataacgcaa
    64681 tctcaaaact gcgatcccca tgatgacata gacgatacag tagataacag tagttgaatt
    64741 tacgagcatc aaaaatgctt gattgacgcc aggaatcagc aaataaaaaa gtgcaaagat
    64801 tgagataatg acagactgag tcaaaataac ggatttggat acgtcaaatt gattcgtctt
    64861 ccaaaaattg aattttggtg gatacgcacc ttttctagca ctttctgtca ctgtctttgc
    64921 tggtcctgag gcccaagcag ataattggac tgctacacca atgaagacaa gtaaactaaa
    64981 cagattcaca ataagatgtg gcaaaccaag aatttggcaa taaatcgaaa tagattgcgc
    65041 gatattattc aattccattt gtccttttgg tacgacattt gctacaacta aagcattcaa
    65101 aatattgacg aaaaatataa aaattaacgc ggcaaatact ccgcgaatat acgttttaac
    65161 tggattttcc aatcgagtga tatacacaga ggacatttcg ataccagtaa aaataaacat
    65221 gatcggcgca aaataaacaa atgaggatgc agtcgtagta tctggtatta atttgtccca
    65281 tgaaaaactg cctaatgttc cggttggtac gatcccaact ttgatccacg cagcaaaccc
    65341 taataagagc atcatcgtca aaggcacgta caatcctaac caaacaccga cttttccgcc
    65401 gatttttgcc atatcaaatt tcaaattcaa aaaagtgatg atccaataaa cgactaaaat
    65461 gacaactaat gtaaatttgc tgttcaaacc aagcggcaca ttatcgataa tattaccaaa
    65521 caacggagcg agtgctgaag cgaccatcac catcccagga aacatttgga cccataacag
    65581 ccatgagaca acgaaccccc atttttttcc tagagcattc gatacccaaa gttctggacc
    65641 acctttttgg ggaaacattc cagcaaattc accagagatc aatgagattg gaaaagcgta
    65701 caataatact gcaaccagca tgtaaaaaat catcgtccag ctcgttgctg ctacatctgg
    65761 aatatttcgt acacttgcta caagggcgca ggtcattccg ataaaggtca tggtcgtgat
    65821 ttgctttgat gaaccagtat ctttcatctt tattccttct ttcaatagcg acatatgttt
    65881 ttgttttctt ttatttttgt tcaagaacag aaatgacaag gtttcatcga ttcagtacaa
    65941 aacccagtat caccgaaaca tccattgaac gatcttagtg aactgggttt gatacatgaa
    66001 acgaacgatc caacttatag aacgttttat aaaaaagaat atcttggcga ggaatatatg
    66061 aaaaacaggg ggaaatacaa ttgttttgat gaagcaaata attgtctgtt ctccatatgt
    66121 ctcttgttat tctttcacac aaaaatcagt tctattggat gatttcgttt agtttctttt
    66181 ccattgcttt ggcgattttt tttgtataaa aattgaaaat tcgatcatca ttcaaataag
    66241 gagtcatgat agccgcacgt agcagagtga ttttctgttc ttttttccat tcttctttcg
    66301 ttagacccat tctttcaaca aaacgaatcg gagaatcacc gtaatcttct tgtgtaaatg
    66361 tagtatgaga agtaataaac cgttcaccat aaacatcgcc atccatataa gaagaccgat
    66421 cgaacatttt ttcatttaat tcattgatag cgttcaaatc tgtacagcct tgttctttga
    66481 atacccaatt gaccatatta aaatcaggat gattcaatgg atagacttcg attgtttttc
    66541 ctttaacagt aaaagtcaga tgatcgagaa attctctgaa tctttgagct gcctcgattg
    66601 aagccccaat caattgacca tatccggtca cattcaatgg caatacacga tgtgctgtcc
    66661 agactgcggc ggcggttgct ccagcttttg atccttccaa aatataagct cctaacatat
    66721 ctggagcctt tactgatttt tcaaacacat atggcgcgaa ataagaaatg atatttctca
    66781 tatttttatg tttgattacg attcctccag cagcataagg gacatagccc atcttatgag
    66841 gatctatcgt gacagaatcc gcttctgaaa tagctctgaa cccttcatat acctctttgt
    66901 caatcgttac gcagtggtgg aaaacatgat gttcttcaaa gaattcagct aaggaagcat
    66961 acggcacaaa ttctcctgct tcgtttagaa acagtgaacg cgcatagccg ccatatgcgg
    67021 catcaacatg taaatagaaa tagatccctt catcttttaa cctttctctt aattggacga
    67081 ttttatctac actgtctact tgaccttctt ctgtcgttcc tacgacagca accacaccta
    67141 gaattgggat tttttgtcca gctaattcac gaattgtttt ttccaaagca ttaatatcca
    67201 ttcgataatc ctcttgaact gggatagcaa ccatctgatc taagccgact ccgcaaatat
    67261 ctaacgcctt catccaagaa tagtgttttg tttgagggac cagccatttc cctaatcttt
    67321 ggatattttt tccgctacgg gaagaagctg ctttgacctc atccatttct tcgtccgtaa
    67381 agctttcggt catttccaaa atttcttcaa cagataaatt caaaagttcc cactcagaca
    67441 tttttttcac tttttcaggc agcacttcct tgacagctaa aggaatcgat ttgatgcaac
    67501 gggcgtacca taatccttca agattagcaa tagaaccatc tgctgcaatg tgtccccatc
    67561 cgtctgtcat attgaataat gaagcaaaat cctgtcctac ttctgcttcc atttgcgaag
    67621 ttgccataga agattccaat gcaacattat ttgggttcca cagcatcgca tagttgtaag
    67681 ctaataaagc aggcatcaat gtttcagcat tcatttgtcc ccagtaacgg cctgctgaat
    67741 gccatgggat cgatcctgcg cgtaatcgct gactgacttc atccaagacc tctatcatat
    67801 ggtcgcgggt ggctagataa tctggagtga gcttatctcc ttcgctaatt gcaggcatat
    67861 ctgaaggaat ataattttct ctccatccaa gatgttcatc taccatcttg ttcaacaaca
    67921 ttttataaac tggtccattt tcagctttgt cgcctataaa gacggccttg atatccatat
    67981 ctttcatttt tcttccctcc atattttgtt ggtcaatgtc ttgcagatac atgtgtttat
    68041 ctgtaacacc tcttcactat agcgccaaaa atgagaattt tttttttata acatcaaatc
    68101 cacgtagatt tttacaaaca aaaataaata aagtcggatt tttctgataa ttcaacgcaa
    68161 aaaagcgaac aatttttcaa taaatcagtc ttctaaaata gataacctaa aaaaagcgaa
    68221 caaacaaata aaatgactgt ccttcattca ctaaacatat ttttattttt ttatattgtt
    68281 aaaaattcgc aatttatttt ttaatagaat tatctgtttt ccaaatttta taacataaaa
    68341 aacctttttt aacggcattt atatgctttt tcagaaatta actgatgatt tcaaaaagaa
    68401 aacatgtcat aatatttccc atattgtgca aaaaaataca aggcggaggc tctactatga
    68461 ttgaagaata tattgagaaa aatattttaa gacagctgtt tttatgtggg caattctatg
    68521 taaataaaga agtcaatcta gaaaagctct ccaatctcct gcatgtttgc aaaaccactt
    68581 tactcaatga tatcaataac ataaaaaaag aatttgaaga acagatcgct tatacacatc
    68641 gggaaaagga ccgttacact ttatattttt cagaacatat acctcgatgc aagatcatgc
    68701 agcaattgtc tcaaaattcg ttgtttttaa aaacttgtct gctttatttg gaagaagatg
    68761 aacctgatta tcttcaatta actgaatgtg aattcatctc tgtcagcaaa gcttattcat
    68821 taaaaaaaca agtattagct tattttaatg actgcgggat cgaaatcgac cgctactccc
    68881 ctcgattcac tgaaatggaa agacgtctgc tgcttcttaa tgtgtcgtat cgtttaggcg
    68941 gttttaattc ttgggagcta cctgaatcgt tttttgaacg tgccgatcgt ttcattgaat
    69001 ccgtaacgga aaatagtggc agattttatg ataaagaaaa taaagaaatc ttatcgattg
    69061 gttttgctat cagtttccta cgccagcaag tgtgtgctgt gacaatagat tcaaaattta
    69121 tcgaagaaat caaaaaacgt cctatttaca attatgtcga atcagcatgg gaaaacactg
    69181 atttccaaac ctattataaa aaagaagaat tcgcctttat tttgacacta ttcaatcttt
    69241 gtaattatgg tttccattct tatcagttga ttgcggaaga ctttcaacag ctacaccaag
    69301 tgtttattga caatactccc gaaataaaag aactagttgc tacctttgaa tctcacttca
    69361 atcaagaatt attcggaaac caaccgttcg aacgtgcgct gattcatctg atgcgttcgg
    69421 cttgggataa ctatcaatta ttcatgccag aaaaatttta tcttttaaat gaggaacaga
    69481 caaatttata taaagaagtc cagacaattt tttccagctg gtccagccag ttaccttatg
    69541 atctacggtt gaatcctaat tgcatgcggg cttttgtgat cgaattgagc ggaattctcc
    69601 gtctgacaaa agaacatctg actatctata tcgtcacaaa ttcggatgtt cattatctga
    69661 tttatcggga agccttggaa gctgtaacta ctttcgattt tcaagttgca ccaacaattt
    69721 attcaagtat atctgatata aagaagtatg cgcagcagtc ctcaaaccgg gtattatgtg
    69781 aacgtacatt atatacacca gatgcggtcc aatatgaaaa tattattcct atttcgatca
    69841 atacgatcga tcgagctatc atttcagctg tgcaaaacaa ataaggggct gtgacaaaaa
    69901 tcatgtcaca gcctcttatt tgttgaagat gcccatttct gtaacaatct cttgatacac
    69961 gtcaggctca caacctcact tattttggac atctacgggt ccgatctctt tatttaaaaa
    70021 ataagaaatg atggttcgga taactaccaa cgccgctagt tggaaaatat cctgcaaggt
    70081 aggtttgata atcgattcga tgatcccagc tgaaacaaga atttccaaac ttagaagtat
    70141 atagcctccc aacatctttt taatagcatt gttctcgctg actcggtcgc tttgcacttt
    70201 tgtatggaca aataaatatt tcaaaaaatc cttgattgat agacaaacac cccaaaccaa
    70261 taaacagata gcaaagatat caagtcccag tacaagtttt tcgaaatatg gaagaagaaa
    70321 ctgcatcaac tctgtcgtca tcctacctct cctcttcttt gtttttcttt gtcttctatt
    70381 tcctgattca agaaataaga aatgactgtt cgaatgataa taataagtgc aagcttcaaa
    70441 atatctgtcc aagtcggctt gataactgac tcgatgatat cagcaacgac tagtacttcc
    70501 aagcttaaca aaatataact tgctagcagt tttcttgtat ctgcattacg agtattacgt
    70561 tctgcatagt ttttcttgac atgagaccaa tcaaaaagtt tgaatagaac aagaacgatc
    70621 ccgacaatta agataccgat agaacaaata tttaaaatag caatgatcca ttctagaaat
    70681 tcaattaaat ttgagcgaaa catatacgct acctactttc ttttaatttg ttcctattct
    70741 tttattgtaa aagaaagtta ccttgttcgt ctatttaaaa gttgttctaa tgataacggt
    70801 tcgcttaaat ttttcttttt cactctccca tttttctccc tccatccata aatcgtggaa
    70861 gtatccaaaa caacgtagca agttaaaata aggcttagtc cgtcatcagc ttttcaaaga
    70921 agcactgtct cggtgctttt tttgtaccca aatttctaaa aatagaacca tacacctcct
    70981 caaatctttt cttcttacct accctatttt tatttacagg aaaatcagac acttcttctt
    71041 ttttgtcaaa atttcctttt tcttctcgtc ctatcatttg gcattctaat aaaaacgaac
    71101 tatccttgga tatagaaaga gaaaacaagg aggcgttttt catgagtaaa aaattaatca
    71161 aagtcggcat cggtttaggt ttgcttgccc ttggcgctgc atatctagga aaaaagacag
    71221 gactattcga agatgacagt catttatatg atgaattcga atcaatctag catcctattt
    71281 agttgaatca ctacggacat acttggaaga cattggagga atcacaatga gaaaaagtaa
    71341 agcaataatg attggtgccg gtattgccaa tatggcagcg gctgtttatt tgattcaaga
    71401 aggcaaatgg aaaggggatc agatcacctt ttattcattg gatgatcacg gttcaaatga
    71461 tggtgcaccg accgacactg tagtggatga atattggaat aaaaaccatc cattagaaaa
    71521 ccaaaaaggc tatattgctc gaggcggtcg catgcttaat taccgtacct atgtagattt
    71581 gatggatctg ttaagtcgaa taccttctgt tactgagcca gggatgactg ctgaagaaga
    71641 tacgagagat tttgatgcaa aacaccgaac ctttgacaaa gcacgtttga tggaaggtgg
    71701 caaaggaatc attgatggcg gaaaactggg attcaataat aaagaccgta ttcttctgac
    71761 taaactgatt gctatgcctg attcagaaga agaaaaacta gacaatatca ctatcgaaga
    71821 atatttcaaa gatgatccac acttttttga aacaaacttc tggtttatgt gggaaacaac
    71881 atttgctttc agaacacgta gttctgctca agaattgcgt cgctatatgc atcaaatgat
    71941 ttatgaattc actcaaatcg aacatctagt gggcgtcaat cgaacacgtt acaatcaata
    72001 cgaaagtatt atgcttcctt tgatcgagta cttgaaagaa caaggatgca aaatcatttt
    72061 gaaccgccgt gtcactgact gggaattcaa agaaacaccg atgcaagatg aaatcactgt
    72121 gactggtttg aaaattacca atacactgac tcaagaagaa gaatacgttg tggtcgatga
    72181 agatacagca gttattttca ctaatgggtc cattacagat tcagctactt taggagatta
    72241 cgaaacacca gctgtagaaa atatggatta tggtgcagct tctagtctct ggaaaaaagc
    72301 cagtgaacgt ttctacaact tgggaaatcc tgacaaattc tttgctgatc gagatgcaag
    72361 cgaatgggtc agctttaccc tgacgacgaa aaaccatttg ttgttgaatg aaatcacccg
    72421 tatcacgact caagaaccag gaaatgcctt gaattcattt atttcaacca caccgatcac
    72481 gccgttaggc caaaaagatg tcaatatgtc tatcgtcgtg catcatcaac cgcattttac
    72541 gtctcagaaa ccaaatgaaa cagttatttg gggttatttc ctttatccaa gacgacgtgg
    72601 cgaatttgtg gataaacagt atattaaaat gaatggaaaa gaaatgctag aagaactgat
    72661 tggacaactt tcaaaagtag atcctggacc agtgaatatt cgtgaaaaag aaacagaaat
    72721 tttcgacagc gtaataaata atatccctgt ctatatgcct tatgcttccg cgttgttcaa
    72781 taatcgtgcc aaaagcgatc gaccaaaagt cattcctaaa cattcgacca atctggcctt
    72841 tacaggagaa tttgtcgagc agccttatca gatgatcttt actgaacaaa gtgctgtacg
    72901 ttctggagaa atcgctgctt tccattttgc gggtattcct atgtcccgtc ttgtcaaaac
    72961 accgcgttac gacaaagata ttcctactct agctcgtgcc gcaaaaaaaa tgtttgaata
    73021 atcaagaggt tgtgaaaaag ctgccctgca tcaagtaata agaacaacca ggctaaaaca
    73081 gcttcttatg tttttgattt ggttggactt attaccgcag atgcaagctt ttgaacaccg
    73141 tttaccaaga ggttgtgaaa aagctgccct gcatcaagta ataagaacac ccaagctaaa
    73201 actgcttctt atgtttttga cttggttgga cttattaccg cagatgcaag cttttgaaca
    73261 ccatttacca agaggttatg aaaaagctgc cctgcatcaa gtaataagag cagccaagct
    73321 aaaacagctt cttatgtttt tgacttggtt agacttatta ccgcagatgc aagcttttga
    73381 acaccgttta ccaagaggtt atgaaaaagg cgtttagttt cgagtatgaa gaaaaatttt
    73441 gtgaaaatgg ttcctcacgt ttttgcataa atttgactta ataccgagaa actgatccct
    73501 tctgtcataa cctcttttta tttatgtctg tttctttttg aaaacaacta ttttttcaac
    73561 gtttactctc ttgccaatcc aacatcatct aacggataca actatttcaa tgattaccat
    73621 tacactaaaa aatcggaaac acacctctcc gaacacaaat acataagact atagaatgtt
    73681 tcatttaaga aaaaaagcgt ttcattatca aaaaggtaag atctccttta aaatgaaatt
    73741 atctgtagta ctaataatgc agacaatttt atgaatctga aaggagcatc tccaatgaaa
    73801 gcagtcactt ggcaaggaaa acagaaaatg gaaatcagaa acgtagatga tccaaaaata
    73861 ttagaaccaa cagatgcaat catccgtatc acagcaacag ccatttgcgg ctccgatctg
    73921 catctttacc atcatggtga agcagttttg gaaaaagggt atgttgtagg acacgaacca
    73981 atgggaatcg ttgaagaagt gggatctcaa gttcaaacat tgaaaaaagg gcaacgtgtg
    74041 gttatccctt ttaatattag ttgtggtcat tgtcatttct gcctgaatca catggaaagc
    74101 caatgtgatg aatcaaatcc agatcagtta tatggcgggc ttttcggatt tggcaagttg
    74161 aacggtaatc attggggtgg tcaagcggaa tatctaagag ttccttatgc agactctact
    74221 tcatttgttg taccagataa tgatcttcct gatgaaaaag ttttatttct atcagatatt
    74281 ttgcccacag cttattggag cgttgaaaac gcaggagtaa aaaaaggcga tacagttgtg
    74341 attctaggtt ctggtccagt cggtctattc gctcaaaaat tcgctgttat ggctggagca
    74401 gagcgcgtaa tcgcagtaga tccagtacag caccgtctag ataaagcggc taattacaat
    74461 ggggttgaaa cttatttctt agaagacacg gcacaagctg gaacagaatt gtatgaactg
    74521 gctaaaggtg gcgcagatgt cattatcgat tgtgtaggaa tggacggatt agagcctgtc
    74581 aaagaaaaag cgaaaaattt agtaagctta caaagcggca caatctctcc attacagatg
    74641 gcatcgcaag ctgtcaaaaa atttggaaca gtccaagtaa ctggtgttta tatgactcca
    74701 gcttcttctt acccgctgca agaatttttt atgcgggata tcgctgtcaa gcatggacag
    74761 gcaccaatta tccatctaat gccaaaaatt tacgcaatga ttgcagaagg actattcgat
    74821 cctacacaaa tcattactca ttcgctgcca ctatcagaag cagcacaagc atatgagatc
    74881 tttgacaaaa aagaagataa aaatataaaa gttgttttga aaccttgaat tcagtaaaaa
    74941 atacaggtga ttttctttat gcccaaaatc aaacgaaata cccatgagat cgaaatagga
    75001 aaagaagaag atatcgaaat acgaggacgt cgcttccgct tctatttcca aaatcgttac
    75061 acattgatct cactggctgt cgatttatta accgggattt tctatatttt tggaagcctt
    75121 gcttccttaa ctaaaatccc cgatcgatat ggcacctatt tttatttggc tggtgctatt
    75181 ttcttgacga ttcgtcctat tctcagaatc gtaaggaaca tttttattta cgacgaaaaa
    75241 aaagcaatga agagaacaag caaaaaaaaa gaggcatgag aatttttcaa atctcatgcc
    75301 tcttttttca ccctatcgta tcactttgat acagacgagc ggtcgtccca ctttcttcct
    75361 tgaccattgt caaaaatgtc cactcgtatc gttcataaaa cgtggtatga tctgtaatta
    75421 agtaaagttt ttcgtaccca agttgatgca tttcttttct gatttccgct aatatccgct
    75481 tggctatccc ctgcttacgc ttttccggtt caacaaacag ggcacaaaga tttggtgtca
    75541 gatcagggcg gttatggaag tcgttttcaa tgacgcccgc tcctccgacg atggtttctt
    75601 tttcatctaa gaccacatac cattgaggaa tactttcctt attagcgatt ccagtacgaa
    75661 tactttcctc atacacaaca gcaggaactc cccattttga tgaaaaccaa ttcgcgcttt
    75721 gttttactaa ttctgggtgt tctcttaatt tgatccagtt atatgtaacc aatgtttaaa
    75781 cctccgacta aaataaaacg tttacaaaaa ttatacaagt ctttatgaaa attagcaatg
    75841 acaacaatag tgatgtaaaa aaaaaacgga aaacaatcac ttgttctccg ttttttgatt
    75901 aatcaagcat ctaaagcttc ttttcttctt tcttggatcg tagctacctt gacgaacggt
    75961 agatagatca aaatagaaag aaccaaattg acagcggcta gtacaccacc tgcaatactt
    76021 tttgttgcca atacaccgcc aataattggt ggagttaccc atggaggcat aacggtagct
    76081 gctggcacta aacctgtaga agtcgcaaag taagcaacac taactaagac cattggtgtc
    76141 aaaataaatg gaatgaacat gatcgggttc aacacgatag gtaacccaaa catcgttggt
    76201 tcattaatat tgaagacacc tggcgcaatc gacaagtttg ttacaaccat atatggtttg
    76261 tttttacgtc ctactaaata aatagctaac agtaaaccta aagttgcacc tgttcctcct
    76321 aagttgacaa agctgtcaaa gaaaggtttg ttcacgataa acggtgcgct atgcccagct
    76381 gcgattgcat taacgtttgc ttcaatggct ggcgcattga ttgtttgcat caaaggatcg
    76441 accatattcg ctccgtgtaa accaaagaac cataagaatg gtgtgataaa tgcaagcagt
    76501 aaggcagatg gataagagtt tgcaagtccc ataaatggtt cttggaccac tgtatagaaa
    76561 gaacctacga tatcatcaac accgaatgca gcaaaaattg cagcaactaa agcaaacgca
    76621 gagatagtga tcattgctgg tagtaatgaa gcaaatgctt ttgcaactgc cggtggcaca
    76681 ccatcaggca ttttgatgat caatttttca tttccgctta aacgtacaaa gatttctgtt
    76741 gaaataatcc caacaataat agcaataaac aaaccgtttg agctcatacc taatgctccg
    76801 cctaaagcga agaaagagcc taaagaaatc acacctgcgg aaacaccgtc ttttcggtag
    76861 ccgttagcta aatgataagc aagcaagaaa gcaatcaaga cagaaagaat ggcaaatgta
    76921 ccgttccaag cagcagcccc gaatcctttc catgattcac caccaaaaat tgagttcatc
    76981 aattcttgga acccgggaat cggtaagtta ttgatcatta ctgctaatgc tcctaagatc
    77041 attaacggca tactcaccat aaatgagtcc cgaatcgcaa ctaaatgccg ttgtgcacca
    77101 atttttgatg ctacaggtat aaaatgtttc tccataaatg caacaaattt atccataaat
    77161 cttccctctt ttctttactg tagattacgc gttcaatcga cgatacagat caatgatctc
    77221 ttttgctaaa tctgtaaaag ctatagatgt catcagatga tcttgactgt ggaccgtcaa
    77281 aagcgtgact tcaacgtgat ttccttgtgc ttcttgtgtc agcatctctg tttgagagtg
    77341 atgtgcttgg actaaagatt cctctgcatc tttgattttt tcatctgcta aagtgaaatc
    77401 accttttttc gcagcagcaa tcgcttccat tgcatcgctt tttgcatttc cgccaaacat
    77461 gatcagaccc atgatggctt ctagattttt ttgatcttcc atttattgta tcctccgata
    77521 atttttatta tttgtttatt agtttttctg cttggtcgag tactttttca ccattcatca
    77581 tgccatagtc agccatattg attacatcta aaggaatgcc tttaggtgct agcttttcag
    77641 caaattgatt ttgcataaag cgtacttgcg gtcctaaaag taaaacgtct acatttttag
    77701 attctagttg attatccgca tctgaagcag atacagcaaa gatgtctgct tccattcctt
    77761 ttgcttctgc tgccttttgc atttttgtga ctaggagact tgtactcatt ccagctgaac
    77821 atacaagcat gattgttttc ttttccattt taaacacgtt cctttctata cttacacttg
    77881 tatataagca agtagcgtgc caactttaaa agcgctttaa aaagttgata tcatcacatt
    77941 taaggtctat accaagttgc atacacacta aaaaagaaag cgcacactaa acacacaaat
    78001 taatttttat tacctttttt cttttaacgt gcacaaaaaa agttgtgaca caaaacttgt
    78061 cacaactttt ttcaaataaa cggtattcaa aagcttgcat ctgcggtaat aagtccaacc
    78121 aagttaaaaa cataagatgt tgtttttact ttgctattct tattacttga tgcaggacag
    78181 ctttttcaca acctctcaat aaacggtgtt caatcagctg accctgggta ttagctcaaa
    78241 acgctggatt cacaacctct tttatttcaa ataaccagta aatacaatga acatctacaa
    78301 aaaacttcta tttatttata gatttcgtca ggcaaatcca attctctctt atcaatcaaa
    78361 gtctgatacc acgaagcaga ttttttcaat gttctgcttc gttcatcgtt caattcgatt
    78421 cgaactaatc catatcgatt cttaaatgca ttcattggtg acacacagtc agtgaatgcc
    78481 cataacatat agccttcgca atttgcgcct tcttctgttg ctttgatcaa gtaatgcaaa
    78541 tgctgtccga taaattcgat acggtaatca tcttgcacga ttcctttctc atccatatac
    78601 tgttcttcat attctcttcc cataccgttt tctgttatca gccaagggat attatgataa
    78661 ttttctttta gatacatggc tatatcatac atgattttcg gatagatttc ccatcccctg
    78721 gaattattca ttttcttccc aggtaaatca aagacttcat aatatcgttc aggatggaaa
    78781 ggtgtctctt cattccattg ataacgaggg gcgcgaacgc gtttaggata atattgattg
    78841 attccaagga aatctactgt atgatgctga atcgtttcta aatcctctgt tgcaggatcg
    78901 aaataaatcg attgtttttg acacaactcc aggaactctt ctgtgtagta tccttttacc
    78961 atcggatcaa aaaatactcg attataaaac aaatcataca tataagcagc tttttggtct
    79021 tctggagaat tggatcgagc atagaccatt tcaggattta aaatacagcc aatccttcca
    79081 ccataatttc cgctgcggta aatctctact gctttagccg ttgctaaaac tttatgataa
    79141 ttccacatca tccacttttt tgtgttttgt tcatgcggcc agcgaacagc atccaaatag
    79201 caacgcgttt ggggaacgat tggttcgttg aatgtaaacc agttttttac cctatcaccg
    79261 taacgatcaa aggcaatttg agcatactta gcataaaaat caactacttt tcttgaagac
    79321 cagccatcat atttttccaa aagaaaagct gggacttcat aatgttccaa acaaatcatc
    79381 ggttctacgt ctgcttcgat caaagagtcg atcatttcac ttatatgctg agcatattct
    79441 tcatctacta tacagttctc ataatcagta aaaaaacgag cccaattgat agaagtccga
    79501 taatgtgtca gatggatgga tttcatcaga tccacatcct gctggtattg ttccataaaa
    79561 ttagttgcta cggctgggcc atacccatta tgccaaacaa aatgttcatt tttataccag
    79621 ctatctataa acgaatcctg tccttctttt tttcctttcc aaccttccgt ttgccaagca
    79681 gaagatgcag caccaagaat aaaatttttt ggaatagtaa ttttcatgat ttcctcctgt
    79741 tttttagatc ccatcatttt ccacacgatt tgctactttt acaaatggca gatagatcaa
    79801 aatagaaaca ataatacaaa caagttgcgt aataactgca ccgatatttc ctgctgttgc
    79861 cagataagca ttgacgatcg gcggcattgg ccaagggacc attacaactg ctttcgccgc
    79921 aaatcctaaa gcggttgcaa aataaccaat cgttccagtg ataagaggcg ttaagataaa
    79981 cggaatagct aaaattggat tcagcatgat cggcatacca aaaataactg gttcattgat
    80041 gttgaagatc ccaggagcaa gggataactt ggtgatttgt ttcatatctt cccgttttcc
    80101 aactaacaat actgcaatca gtaaaccgat cgtgactcca gacccgccca tactcatata
    80161 catatcccaa aatggcatag taataatgtt cggtacttct tttccagctt caaaagcttc
    80221 cgtatttaca gcaattgccg ctaaaagcaa cggttcccgt atcggcttca ccatttgatt
    80281 tccatggata ccaatcaccc aaaagacttg cgcaataaac atcaatagca aaatacccgg
    80341 taacccttgt acgacacctt ctaatgggcg ttgtacgaca ttgtaaatga tatcataaag
    80401 gtacattcct gtaagttctt tgatgataaa tcccgcagcc gcgatacccg atacagtcag
    80461 aatcgtcggg aataaagcag aaaaactagc agaaacattc gttggcacgg tatcaggcat
    80521 tctcagctgt agtttcttct gtttcctcaa ccagcaataa agttcaatag aaaggatgga
    80581 gaccaacatt cccaaaaata accctttcgt atctgtatat tgtttagcca atacgttttc
    80641 tactataaca gtctgatttt cattcactaa ttcataaaca gttggattaa cagataaata
    80701 agacatcact gcgatgatac cagggaatac accatccact ttattcagct tggctaattc
    80761 gatccctatc agaaaaacag catagatggt caagaaactt agtgtgacat agctgatggc
    80821 agatgcgata ggctttaatt cttctaaaaa acgcaagaaa cttatctgtg ctaagccatt
    80881 ttccgagtca aagaccattg ctgaaaacaa tgtgccaaaa gcacccgtaa taattaccgg
    80941 aatcaatgca gcaaatgcgt tttttatcac catgatatac cttaaattat tgattctcgt
    81001 tgccacgttc cctaaaacat tggctaattt atccataaaa ctcattccag atcccctcat
    81061 tcctgcttct tctccttgac gtcatctctt tttgtctatt agtcagcgct tacatttcga
    81121 tgaacagaaa ctatttactc ctctttttta ccaaatataa aacaaaaatt catctgatgt
    81181 atttatcata aaatacatca gatgaactgt caattagttt ctttttctcc tattattttc
    81241 tgtaattctc tccgatttat tgccatatgg acagtcattg catcaaacgc agcaagtgca
    81301 ttccgccttt cgatggcctg aacgatctct gtatgaatat cgatcgtctc gattttcaga
    81361 tgctggatat cataattttt attaaacaaa gcaattgatt cattaatgat tgggataata
    81421 tgcagcaagg ctacgtttcc gctagcttct gcaatcatcg tatgaaaatc gatgtctaat
    81481 tgaacatgtt cttgtgtgcc ttctcgaaaa gaagtttcaa tcttttgcgt taattttttc
    81541 atttggacga tttgattctt cgttgcatat tccgctgcca aacctgccat cttaggctcc
    81601 aataaatatc tcagttcaaa taagtctcgt atcatccgat cctgatcttc aatcaaagaa
    81661 aaaccgagtg ggtcattggc aatccctcgc ttatcactga caaatgtccc cgctccttgc
    81721 cgaacttcaa ggatattcct ggaagctaga gcccgcacag cttctcgcac cgtgcttcgc
    81781 cccacctcta aataatcgga caattcatat tcattcggca gtttatctcc tacttgcaac
    81841 tgcatttcct ttaaatatct aaggatcttg tcagtagtta cttctactag ggttttattt
    81901 tcttccaaac cacatacctc cttttcatct gatgtatttt ttcgtaatta ttataacacg
    81961 tttgaatcat ctgatgattt tttgtataca aaattgatta atccgttcat agacatacaa
    82021 acgaagaaga tatttaccat aaaaaagact aggata
//
LOCUS       DAZKKZ010000004        77448 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.004, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000004 DAZKKZ010000000
VERSION     DAZKKZ010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 77448)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 77448)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..77448
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.004"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(61..303)
                     /locus_tag="ACG8LA_000272"
     CDS             complement(61..303)
                     /locus_tag="ACG8LA_000272"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202609.1"
                     /translation="MRLRRNKNYTTIILEDFTDQELLIVGKTKADFIEKGNASIVKAS
                     KVAVEKYFDSLEESAKEIFNGEKAGSYELDGSVAKF"
     gene            519..1574
                     /locus_tag="ACG8LA_000273"
     CDS             519..1574
                     /locus_tag="ACG8LA_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202610.1"
                     /translation="MKEPLLFSVDLGNKSVKEMSTHVSPLSLPSRILNKNIINSGRFS
                     NIGSSLKRSLNVSEYSLVNTTESYYFGKDIHELGKDDYVIESLGFGISRYKQETYQDI
                     LSFSLANLARLEDQSDDVLTVNLVLGLPSSDYTETIVKYVMQQATRQHSVEVDGKAYN
                     INVDTVWVLPQPIGTLYNLLLADDGSVQDESLISQKIGFVDIGGGTKLFDVVQNFEID
                     ENNREQKDTGIFTLYNRIVNMLDLPISPNAFQLEKIIREGKEKGVYLFKPSGNESFDI
                     SEVVEREIKTYTNMVVAEVLATFKNFTTLDKVVFTGGGASIIDKQLVKDKIPHTLFVE
                     DSEFSNVKGFYKFGLTQ"
     gene            1594..1947
                     /locus_tag="ACG8LA_000274"
     CDS             1594..1947
                     /locus_tag="ACG8LA_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202611.1"
                     /translation="MNKGKSERYVVIINREKVSELPLAEFLESEYETLGVKYSQTIKK
                     ALNLYRRVKNNEVTIIEAGNDRNDSKVAEVKNKPTDHNPIQQAHPSTVTSDHSAKKEK
                     PMLKGFNAPSNKDLL"
     gene            complement(2129..2416)
                     /locus_tag="ACG8LA_000275"
     CDS             complement(2129..2416)
                     /locus_tag="ACG8LA_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202612.1"
                     /translation="MKENRFKKFAEAEVEEVPEVVEAVEEPKQTPKETTSSLVAKLKS
                     DSSEKKKNYQFTLQPSQRKKLSKISEKLGIRSDSALLGEMIDNLYDEVFGE"
     gene            complement(2429..3247)
                     /locus_tag="ACG8LA_000276"
     CDS             complement(2429..3247)
                     /locus_tag="ACG8LA_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFQ0202613.1"
                     /translation="MEKKLSIITGNIEKGGTGKTTTIYNLGGYAVENLGMKVLYIDED
                     KSQNLSKRFPDAFSKAKRENTINHLYLHGSAEPLAINENMDILVAGEDLKQVEMQMRD
                     MPNNRTLLFRWIVVNYEQLKEKYDLILIDTHNDAGLLAQNAWAVSDLVVGISDPSKDG
                     FEALLKLGKDIDALAKQLIDIKTGETLMETKYATIGSRIKHNTNSSREFLELVPTLSN
                     YLGYVQEKELLNATSLEGKNIAEFAKDKNIYRKNKDFFESTFTLYNKIIDTAQE"
     gene            3473..3694
                     /gene="relB"
                     /locus_tag="ACG8LA_000277"
     CDS             3473..3694
                     /gene="relB"
                     /locus_tag="ACG8LA_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB family
                     antitoxin"
                     /protein_id="HFQ0202614.1"
                     /translation="MPVISIRVSKEEKDFLEKVAEFNGDNISEFMRSNSLQTAETLVD
                     FATYKQLMKEHEENDQSISHEDMLKELGL"
     gene            3696..3962
                     /locus_tag="ACG8LA_000278"
     CDS             3696..3962
                     /locus_tag="ACG8LA_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA];
                     GO_function: GO:0042803 - protein homodimerization
                     activity [Evidence IEA];
                     GO_process: GO:0030541 - plasmid partitioning [Evidence
                     IEA];
                     GO_process: GO:0051290 - protein heterotetramerization
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HFQ0202615.1"
                     /translation="MTYQVRYEREAQKALKKMDKFQAKVILNWIEKNLVGTDDPRKHG
                     KGLTANKSGYWRYRVGAYRIIADISEHEVTILILSIGHRSEVYK"
     gene            4129..4614
                     /locus_tag="ACG8LA_000279"
     CDS             4129..4614
                     /locus_tag="ACG8LA_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202616.1"
                     /translation="MGWYGDYSSANEVIEEKKGYAKNGLEIVGTKVTKTYGIILFKDA
                     EGTYDIDSFIFRDEMYKPIYFLNDSPAYFKKIPKKWLKFFVGDQEKMVKLQLDRIKEE
                     SNKPKLDDLLVAGKTYSIWDGSYVAVYQYKLKRSFIFRLQDGSLTRFTRLSAGDVKEV
                     T"
     gene            4823..5005
                     /locus_tag="ACG8LA_000280"
     CDS             4823..5005
                     /locus_tag="ACG8LA_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HFQ0202617.1"
                     /translation="MINLFLLVTASTLFFTGISLIISYLIYKKAENHTSKAIGLAVSS
                     FLTLLTLFVTLSFSFV"
     gene            5108..5392
                     /locus_tag="ACG8LA_000281"
     CDS             5108..5392
                     /locus_tag="ACG8LA_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202618.1"
                     /translation="MLTATLQQPTHVAIAESYTINAGIVKQLIKDREFKKFNSRQAYN
                     RQLKKAILKHKDSFIGNLESVDVKTVSTAFSVVEVTIDGRLISLFAFGIN"
     gene            5408..5644
                     /locus_tag="ACG8LA_000282"
     CDS             5408..5644
                     /locus_tag="ACG8LA_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202619.1"
                     /translation="MEGKTFAEIWTEFIEVPTRIDPITSEKVLDADFYNLKAGTSLEC
                     VWMYLEEHFKGVTLGHVLYHNGAEWDAIGNIHFS"
     gene            5666..5920
                     /locus_tag="ACG8LA_000283"
     CDS             5666..5920
                     /locus_tag="ACG8LA_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202620.1"
                     /translation="MNYTDEEQIALEYVFTNEEGEEIEKVLIISSKDLEKALAYEPYE
                     STVTVIEFLDTYTSNDTWEIMNICNANNIQFAEKTNKSFY"
     gene            6002..6187
                     /locus_tag="ACG8LA_000284"
     CDS             6002..6187
                     /locus_tag="ACG8LA_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HFQ0202621.1"
                     /translation="MPKTAREIVKILKSNGFKKTGQTGSHAKFYNSKTKRTVVVPIHN
                     GDVPLGTEANIWKQAGL"
     gene            6254..6649
                     /locus_tag="ACG8LA_000285"
     CDS             6254..6649
                     /locus_tag="ACG8LA_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HFQ0202622.1"
                     /translation="MKTKNIFYPAIFEKEGEAYNIVFPDLPEISTFGNSLEEAYLNAK
                     DALGLALYSVPDAEFPKPSAVEELTLKANQVVVIIQLNIKLFRRSLNTKTIRKNVSVP
                     EWLVLLGKEKNINFSQLLQKALEEELLEK"
     gene            6666..7016
                     /locus_tag="ACG8LA_000286"
     CDS             6666..7016
                     /locus_tag="ACG8LA_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202623.1"
                     /translation="MKATHLNYFSRTLINNLLKDTTGISVSTKHFANDLIIFEDNNLR
                     IEMFIEQATPNSIPEFCYTHTEKMKHAKSVKDVEALSESLTNALNLVKKAKLLFEFQT
                     DYHNELLAQSEILD"
     gene            7038..7412
                     /locus_tag="ACG8LA_000287"
     CDS             7038..7412
                     /locus_tag="ACG8LA_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202624.1"
                     /translation="MKQTQTETVNDTLADQLAGYYKLFEMGKAQRLIHYLWKYKILFL
                     FWESTLTFSVLFYKSDFYNQHLVLGSFLLIYTILMLNLYTYITLEEHLVISDAGIERN
                     IKRVSFKITLNKPTDKKLSEAF"
     gene            complement(7719..8117)
                     /locus_tag="ACG8LA_000288"
     CDS             complement(7719..8117)
                     /locus_tag="ACG8LA_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HFQ0202625.1"
                     /translation="MKYFFCAVFEWKGNEYAVKFPDFPDLYTHGETLEDAFEMAQEVL
                     EGYLVLLELQEKEIPSPTPVQELNARIKRSENVNLFVVKANTKVAKARNKQNYDRKSV
                     TVEHYLNVLAAEENINLSKALNDLLREKLI"
     gene            complement(8309..9076)
                     /locus_tag="ACG8LA_000289"
     CDS             complement(8309..9076)
                     /locus_tag="ACG8LA_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /protein_id="HFQ0202626.1"
                     /translation="MKKDELTKYNEEFLATIDMKMDLKSYELYQLLFSYISPTKLKKT
                     GVVDLPVKAIINYMDVDQNLETELKTIVNTLQRQAVYEISNLDKKYKTYTTVSAIDRI
                     HWDLEEHSVSFSFSEDVIPLIVSIKKKYPFFVFEDLASFQKKYSIVLYKYLAMYYKKY
                     LIAKNKGDFEKAEIYKNPLIEIVKIREITKTENEYKTISNFDRRVLRESVEEINEKSM
                     LNIDFAKVRKGRNYNFAVQFNISSEFDEKTYREKKLG"
     gene            complement(9111..9476)
                     /locus_tag="ACG8LA_000290"
     CDS             complement(9111..9476)
                     /locus_tag="ACG8LA_000290"
                     /inference="COORDINATES: protein motif:HMM:NF018169.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202627.1"
                     /translation="MSVPVPYKQEQRDPAYLKGAEDKTEKMNQSYLKAMNSKYTKLLI
                     KNFLISSADLCDLKLMSRLQNKVYPLYDRLSKDRGFESVVNHLSYVATHKEDYTIKNT
                     VKYLEKSITSYLPYVNLYD"
     gene            complement(9504..9734)
                     /locus_tag="ACG8LA_000291"
                     /pseudo
     CDS             complement(9504..9734)
                     /locus_tag="ACG8LA_000291"
                     /inference="COORDINATES: protein motif:HMM:NF044726.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="initiator RepB protein"
     gene            complement(9756..10271)
                     /locus_tag="ACG8LA_000292"
     CDS             complement(9756..10271)
                     /locus_tag="ACG8LA_000292"
                     /inference="COORDINATES: protein motif:HMM:NF013235.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HFQ0202628.1"
                     /translation="MKITEKNVNPKFETTESNLKKFDLTVTLSNQLVDSIVEMDAMPQ
                     KIYLYAIGHLDPKNPPFNNTVKVSKKALFALMSSSSSSSKHSRLKQVIEKLHQQSVIK
                     IQRTKPNGKTEYKVISPLEITEFNDFSDAVSIKFSSSIMPLLTNLENHFTQYTFDQVV
                     NLTSKYAISFF"
     gene            11315..12118
                     /locus_tag="ACG8LA_000293"
     CDS             11315..12118
                     /locus_tag="ACG8LA_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HFQ0202629.1"
                     /translation="MSQEVTEKIIDSDVDLVSEQTNAIVRYNNGLNTTALRGFKPVEM
                     DVFWAILSKMKRQGTAEVTFDFNLFRYLVKYDRREKDSFYSVLKDLSDKLGNLTYRFE
                     DSDVYEQLWLFQKFRIDKQKETVTIKANEEFEFILNSIGKNFTRFELDNFTKLRSSYT
                     KELYRHLMQYRNKEWRNGYWVVKVEDFRRALSIPSSYRMTNIDKRILEQAKEEFLAPD
                     ENGIQVFETFDYEKIYAKKGRRVDRLRFTFSEPESNLPTISMHNWLEED"
     gene            12703..13158
                     /locus_tag="ACG8LA_000294"
     CDS             12703..13158
                     /locus_tag="ACG8LA_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202630.1"
                     /translation="MNAINWHEFVNYMESLLDDLKSFSIADAVKHGLPVSTTMKLRGL
                     KIPDEIIKLRTKTIIETAKVVDNMNHELKGKKTTYEKDFERFLKSVIGKYLGKKSFSE
                     LRDEEIVPTPMVSKIRKNKAEGNYYLGTIAKIIDYLENKEQKKGTKKGR"
     gene            13277..14335
                     /locus_tag="ACG8LA_000295"
     CDS             13277..14335
                     /locus_tag="ACG8LA_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FliS"
                     /protein_id="HFQ0202631.1"
                     /translation="MEKNVNSTSTKDQYSIIGGLLGDKDKRTRHGLRIMLATFLGVLF
                     LLTGLGSYIYQLGNYNYYLVNNTTPIGSSLEFARSGAEITISDVWTDQNRDVTVVKLG
                     YSQNARKLLSTQGKNYNLYMATKEKDRPKKLEMSYGMLSTDGDAFLFLKGKLDERAYQ
                     VFIANQVSLISGDDTADDDTKVNVNEADSVTKALSQYSMNDVNNEGVISFGKKAKPVN
                     TPDNINFRINPYSDSTNVYQGSFLTKDGDIDYSKVVAVTSKNNVVSKLEDQLNASNTN
                     IKKIEATKAEYLERLQQNPDDKDSQESIRQLDSRMETEIKAINDTQKLIDQYKNADFN
                     KDSFGDMKTTFKYLTLTD"
     gene            14377..16326
                     /locus_tag="ACG8LA_000296"
     CDS             14377..16326
                     /locus_tag="ACG8LA_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFQ0202632.1"
                     /translation="MENSTEFFKNIQTEFNHALTPMKPPKHKLVGRDDELHELSLILN
                     RPETPQAILLGEAGTGKTALASEWAERQRQDGKKVQVYKLSIGQLRVGGDDVLQTRLE
                     TLIPRLKEYERILKSEDKENEFVLFIDEFHKVVSSFGSGNKIGGDSLKEPLANESLQL
                     ITATTRKEYENYIKRDDALGRRLQPLELNELKSDVVVDILRQWLNTSSVKDDPQASFK
                     LSQRIPDELLQEIVQANKLYREDLSEPAKSIAVMEDLIAKDRVDGNAYNRESLLQIFG
                     KYNIQLDSDFDMEKLQEELKSIKGQPLAVYTITMLFKRMKLGFDRFKGRKQPKATALF
                     TGSTGVGKTAMAKAVARGLYGDENKVLLVNMPDYKTKDDAMRFRRLIGTHVRHDPSAI
                     IVCDEYEKAGVETLDAFLSILDEGRISFTERGWDDREVHDTVSLSNTILFATTNAGAE
                     MFDSLNRYSSLSRVTNKENSNEYSTELKREYRKVASGIKQALIGEGLKPEVINRFGRI
                     VPFWALSEQTLLEIAYNEMLKSAELVRKHLNIDLRLPPRKERVYGQNFYADDLSMHLV
                     FDMASQEDSKSGGARNILHLVESEFEEAITEAIITYPNAKIFDVKLSEAGAFEGKGDS
                     NAEIIAKPSVAESKENKIVFSIGGA"
     gene            16329..19970
                     /locus_tag="ACG8LA_000297"
     CDS             16329..19970
                     /locus_tag="ACG8LA_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3659 domain-containing protein"
                     /protein_id="HFQ0202633.1"
                     /translation="MKFKKYLLQNLRIKRWVVRGLVIGGVLAVTLGAPFGMNDPTPDN
                     QDSKQETVINKNVAYAESKPAEQGMWTLYARILMGDKEVNDSAAKTGQMNLLGQGGIS
                     ADFPYSDISKQGNSIAGGNAGTQLASTLATYSYYGYIETVSGNAIASQASSILGSIGR
                     TIGSFIGSISLILSNIAESINELLGKFFMSMNIFSLMGWGEGGSDVSNPVSKALTSLL
                     NNLGLNNELFKAIASLSMLFFTAILGYQGMKLLSKDGVNSKGLSPVLEKWIVRIFVLF
                     IFLPVAGSLLGVYINGIQSAKKDGDIPTNVVSDYIINTRLWASTQNLAPSSDTGGDVP
                     DGKPTSEIKFVDTDYEPSKKSAMIRAINTSSYARQNNDLDSNSVGMALLKEWSSNDTF
                     NINTYAGDVNVAENDAYMGRAPAVWTGYNLGDGKEGSAIKKPTNLNGYIWSANQNVTD
                     DNRKPDGKGTAHNFDATQPWGVANNATFSTQSVALLLQSALDTSGAKFYAYNIAPSGI
                     QGSAKNMSTVKTEWRTASLVGHGAMGKFGSWLAMNAESIVLAVLYLACAWAMFNVNIV
                     KAFKREFIRIWEVVLTGSLASGAGVMAISLGVVTTSLIGLQLPIFLITFIRAFGDTAV
                     GFIPNTLVGDGVANIVRSAMILGVGYLLVFKKGEKVNNLINMLIGLPLEVAFGFDERA
                     KLLFGNRNDAVRVVDGVSKAIKKSQGAKNPYYDGGNSSVKDMVAGGLGAVGAQKMAER
                     LNNMGDSNADAKSIADKVIPETPEGMSFNGGGVGSTINNTSFKDLVRQDQLRNNSQQY
                     IDHLGRMVDENGNFVDENGEILKDSKYGKDAKGNFIDEKGRLVDEDGNLIDTNGKPLE
                     DSEDGNIGMDSEGRLIDEKGRLVDEDGNLVDENGRRLLNGDFGHDSNGRLVDEKGRLV
                     DEDGNLVDEFGNKLGKHSDGYNVNGDLVDEDGNIIETRDALVADRNRELEQQRHTPIA
                     VAIPENEEDEITLDQTHQELRNEMSGEDVSDRVHRELGDGASGESQSRELNSNFDNSA
                     IRNDTVLKDRESLTKETDKEQSDVKKKFIPTPNVNQTDKYETNIGSGMSKDNQSIREP
                     ELTNKNNRTNNSKSTSDNSGKSNQSTKKTSTAKSAVEYLSKTGKNVYTSADKALAKAP
                     KGSLAGITYEAKNEAIKIGKGTAKVAKATATGASKTGKVVKKSTMSVKDYIVKYGNQK
                     STENKSEDE"
     gene            20370..20708
                     /locus_tag="ACG8LA_000298"
     CDS             20370..20708
                     /locus_tag="ACG8LA_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202634.1"
                     /translation="MFDSIKNLVSGMTPDMKTLVQVVLYFLAFVFSLKPGFTAMKFFG
                     DAKWGDGLKYVGAIIAIFIIPVITTVMLYTMGTKTGNDLNQKANIISALIPVVGIYLV
                     SKFPKNELLG"
     gene            20794..21039
                     /locus_tag="ACG8LA_000299"
     CDS             20794..21039
                     /locus_tag="ACG8LA_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202635.1"
                     /translation="MREESKCKMVFDREKMLAHANEVLMSSLKGTELAKIMNMNVNQF
                     YDYRNGSKKIEKARLETLIKFEKAYVYMLDKQKRTID"
     gene            21059..23215
                     /locus_tag="ACG8LA_000300"
     CDS             21059..23215
                     /locus_tag="ACG8LA_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202636.1"
                     /translation="MAKFKDITESINYVAETVPVVALSLKPQLLEVYKKEEKEAKAKK
                     AKAKVWKEFDALLTKDLPKKNYMVIEDVQKLNSEGVIDEDDAILDSEKYVVLLKSSLN
                     YVADLPEKFKEKLLAGVRFMDSSGQLLVIPDDPNVFESEVEEATDFYSAVEQLEVATN
                     GLERIAETFNSSEEVEFEAVAENVPDEKEALFVDDNKPTEAENQEVSIEETQIQTETY
                     QQPKIDEKPESQSDKENYVYEAEKITSESDVPKNLDADFLEKNFEQIIADKFQPVVLD
                     EINDPVDLNEEMLSIPELKPLLFLAKESMNARISIANNKINSELNKTKEQLILKGKQM
                     LADELLRIEEATSLNGQNQFTNTLSVAKESYEAEASKIDDLVMEKSNIIRKDYDMAKQ
                     AYLDAELKKLEQRYDAEHLPEVKQQEDEYRKATEESLDQQYQEAIESIKNDALKQSQE
                     AKEVVVERIINSLKPEIEKSLTDVQEKTLEIVEKTKSENEAEFHDTKEKTTDVVVKYF
                     ANKEEVEKQVANNTKELETKLVEQQKTIEEYKDRMKEVKDLAEGYKLNSEKLAEQSEA
                     LREDLSRSRSDLAQMAEKTKSLAVATENQSSSKRDFTSKKMATIISVAAMACGTILGS
                     SYFISHNNQQAQAQTQTSISRVENSIGTNTNSASTNSSYEATPTTEFKVGKDVVISID
                     GKTTKAEVISIDGEKAVVKTPDGNQYKIQAHLSDNN"
     gene            23227..23460
                     /locus_tag="ACG8LA_000301"
     CDS             23227..23460
                     /locus_tag="ACG8LA_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005576 - extracellular region [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HFQ0202637.1"
                     /translation="MREEKIVYPVIQNNQENMTSSQHLQEAQLVYQVNELPQTNETMS
                     KSISLIGLLIVAIVITVGVYRKLNVKGSISDGR"
     gene            23450..24316
                     /locus_tag="ACG8LA_000302"
     CDS             23450..24316
                     /locus_tag="ACG8LA_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202638.1"
                     /translation="MADNSNYGFKHNLHQKPSETIVRVEWLEKHVNSTYSVTAKRLIV
                     SAIVVAVVVLGSIVYLVSDTIKLKFIFVPTLLMIIGFLILISQYMFIDPSSGSLISGS
                     IRLFKSVVNSARVSMGKKKPFRGTEILKVKQDGTIVYRDGSVALMFNLDGATSLTAFP
                     EEVMAQESKSIQYQNTRDRSLAEIKITSSQPQNTERQTRNMKIQKRNARSNKAVFDII
                     DQQERFVSEYIDGVKTTVIQYLILKSQSKMVLDEGVERLENYTSRGLYYSVTQLSAKQ
                     TKEILSDIYALK"
     gene            24331..26301
                     /locus_tag="ACG8LA_000303"
     CDS             24331..26301
                     /locus_tag="ACG8LA_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202639.1"
                     /translation="MEIMGRSQLLNFKKKRKTKKEQKTRNSKVVNNTFVSDLTSLVGY
                     QFTPSYIRTGKRWGTIVKLVNTYGMNRNYGFGWMVKAIPEVRVEGVKAYLIEADKPVS
                     QKDQQEIMHENVGGSTNSYENNLEGKNSDAEISKTVMRIMDLNTASLLDSMANKIIDW
                     KLEILLVSDSPNKISEQLIKLQRLYDEKMYGLKLMSYGGDQRDLFDRLLSEPIGNVYE
                     YTSMSSDFAGNDHAIRKGLDDANGWAIGTMSTSYASGVAFMALDDSFTSKVLVASHKN
                     ATIKGYDEKISASSLWGQLIANNAMANHKRTFHIVLNKFDYFGDPTGRTFVAKPSLNS
                     VIEKVNLAEEGLNSLELFGNQKDIGDLYRRNLDKLTQIFYLLAGRTLDSATRVLLKKE
                     LGNFYISQKLWDINYEERSKLLVNSSDTMPVLGDFISYLTNAETKAKKSGTEKEVDRI
                     IVLKDTLRTALDSFSRMFNQRTTLKEIGKSDKLQFYYNLGDLRAETNVMEAQFLNTFD
                     FITSQAKKDDIVMIHGFDKLSIETVGLIKKRLTMLEEDGIRLAFLFDTIGSGEDNEYK
                     EDIETADIFNTDGKIYQSFESDFNYTIIGKMTSGELMKYEKKVAPARKGEDDQKLSVD
                     LRQYLTTGRSNKFQIRRPVDLTNNFVIGEFIL"
     gene            26468..26695
                     /locus_tag="ACG8LA_000304"
     CDS             26468..26695
                     /locus_tag="ACG8LA_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202640.1"
                     /translation="MKPNIKILDRIFLGRDTEVILIQHEEGFEVSIGIQKLQKPHYCN
                     QLYKNFTDEEKARVFFNEVKGMREQYEVVEA"
     gene            26692..27186
                     /locus_tag="ACG8LA_000305"
     CDS             26692..27186
                     /locus_tag="ACG8LA_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202641.1"
                     /translation="MNKLPEKNRVFRLKGDLSQFKIDENGQFFVWMRHEHCWCNPFVL
                     KKENEIRTKIANGEWDYLFRWEDESFIANDMDHAFVSFLDNTWGTWYDCYLEKLGFQN
                     IDIDAIECLKEVDQKYEEEPYYLLQQKLANNSVFQVEIWENEDGTYEGLAQEIPFSDR
                     KSSI"
     gene            27361..27696
                     /locus_tag="ACG8LA_000306"
     CDS             27361..27696
                     /locus_tag="ACG8LA_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202642.1"
                     /translation="MKQYLNEWKAIEGSLVTQRIKELPDCLEKDHLFQIREMLKKEQF
                     DPDQFLVVEYPTIGVYCCNHINDGKYFIIQEYGGQLTPFYTTWEMSEEGINNFPCESI
                     EDSISHTEC"
     gene            complement(27953..29536)
                     /locus_tag="ACG8LA_000307"
     CDS             complement(27953..29536)
                     /locus_tag="ACG8LA_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202643.1"
                     /translation="MFILDDEIKKVKNPRIIPLLEEVRSSFYQGNYRSAIAVNYSALI
                     LDLIDKLSDLANIYEDNTSKKILEDIARLRKSDPNSPKWEMELLEKAYSSTELIDSYE
                     YEDLKYIKDQRNYSAHPVVTYNGNTWELRDITKETCQDVIRKSYEIIFLKNPILGKKV
                     TIEIIQYASRIHAMSVTPEEFHSALKNSYLNKLSEKAKENLCKTAFKFVFQLSYGNEE
                     ADRNRESTFRLLNALIFDNKEFYLNILKKEIAKYRFTAESREEINKSLGENQQITYTK
                     GFFLLTFIATHPELQHDFSDETIQNLQISINDFKPKQQVLTEIEYYYRLRSLAVLGNN
                     NEELQNHLNSLVDPILQQKMRVSSLPSSTLETIYNQYLYFGEKEMFIDFMIEHLTDAS
                     SFRLADKDMEVLPWIYNKLNQEQFNKLLYNLNGNNQFYKNSNFPPFISNLLDFYNQKF
                     QVNLRKHYSGLLYPNAVTMDQGFQLKDKELKKLYELAESKSDMYLDIIDNIINKSEDY
                     LRKEINSEKELLNYVHKIK"
     gene            29658..30242
                     /locus_tag="ACG8LA_000308"
     CDS             29658..30242
                     /locus_tag="ACG8LA_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202644.1"
                     /translation="MDLKQSFYIWLYPDNPMSIMADIFVVSILLYLFYLIFFHNLIGY
                     MILDWKGMFDIERKPFANNQTYTVFESGDWEENEVDVIHEIGLALSGIQDADVLVSMT
                     TDTGYNAYEVFYLMYFIWRDGQEIINGRAEKTINSNTEISFCMGEGEMIVYKDGSANI
                     KTAFGDIETSIKELREYVQNPYNFQYLAGRINLV"
     gene            30253..30498
                     /locus_tag="ACG8LA_000309"
     CDS             30253..30498
                     /locus_tag="ACG8LA_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202645.1"
                     /translation="MKKIINQPTNHLIIEGVIFVTMYFTVGNGISNTIIQKNPQYLLF
                     SLYAWIVQMVWVSILMLLFYWIVRVILLLLNKRKKDR"
     gene            30504..31226
                     /locus_tag="ACG8LA_000310"
     CDS             30504..31226
                     /locus_tag="ACG8LA_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202646.1"
                     /translation="MKSTKLKVVLLSTAALITLTACGTTNSADNNKDTKSSSTVVTKN
                     SSTSASTTISSMTENNAEKYQKYEDINKGQKPEEVYTDFINTVKNDEDYGNDPLQNKN
                     LTIVLYKPDCPDCQKAESKIMQEIKEGFSYAPTLMHDITINKPAYEYHAVAVDITDGV
                     PEWIQNIPGLADENNQYHTPTVAVVTPKKVNGTLYWDVMGMTTNTTDEMIESTTKYYM
                     DLGAYKLYQQSEPVMDDQSKVK"
     gene            31357..32100
                     /locus_tag="ACG8LA_000311"
     CDS             31357..32100
                     /locus_tag="ACG8LA_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202647.1"
                     /translation="MKEISANEAHIPQKNQVGIYKVLHGEGIYKIQLLTGYNNGANGK
                     WLKAKSIRELKTEVEKIRLGLTREEISRLSENSSFVIQKEKEKHLLHRELIIEKYYDV
                     DLPDQLRIIDEFSEKKWKSEIYPSLIQYKASGKPMYNYTGFLNYTQYKYAFRKLKGIK
                     QADIALYEMKKMDRLKLIQELVQNTWNQAIVELEKENGKILTNEYLIVNEIEELIGLF
                     SCENGEVFLKSSPIYSILDSPYQFIQVRR"
     gene            32106..32471
                     /locus_tag="ACG8LA_000312"
     CDS             32106..32471
                     /locus_tag="ACG8LA_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202648.1"
                     /translation="MSSLKDDYIQAKQEYEKIQMLKSEKVELFLTQKLAEDHIANLDA
                     KTLEEYDQQFNQTHHNIILLVDQAKRRLEKAEYELLDQGIICLDKGIRRYYSAELKKQ
                     NVDRHALKHEILELIMQRI"
     gene            32487..33017
                     /locus_tag="ACG8LA_000313"
     CDS             32487..33017
                     /locus_tag="ACG8LA_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202649.1"
                     /translation="MSQNISAVKQLIEKDLETTVQRLAERIHFANYQTISNWSSRNRN
                     PEEIPMKFFYRIGKEYGVDPIKIFEKTMIYYYHGTPNEVLEHLLEEAEEKSSILEISQ
                     NDKAIQVKCVDPTGKIIVGFDIERKSKIDFITQLTKINNLNILTLRPDHEQLFMSFKK
                     QLKEIQKRYNKVFSNA"
     gene            33179..33547
                     /locus_tag="ACG8LA_000314"
     CDS             33179..33547
                     /locus_tag="ACG8LA_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202650.1"
                     /translation="MWNNKLKTGLLLIVISCAMMVGMIIQREQSYFEVSANNVIERCH
                     YGQHFWTGEVRENIDREYVQRIVWDAYSIKDYPKSLTSRLFYSEKDNQKLSNLMMKKV
                     RKLAQNYLEEKEGNSPIDKN"
     gene            33738..33998
                     /locus_tag="ACG8LA_000315"
     CDS             33738..33998
                     /locus_tag="ACG8LA_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202651.1"
                     /translation="MAYENLQLVVAEVSGDIYLTKVKDGIMDTNYRRVATDDVLSSST
                     EWFRKNEESAVHFEGIDGNIHSLFYTKDKEKAKKILDILKGR"
     gene            34616..35416
                     /locus_tag="ACG8LA_000316"
     CDS             34616..35416
                     /locus_tag="ACG8LA_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202652.1"
                     /translation="MSKDLRELKLRKKQYNQYFSSLLNKHIEEGLDHDFGKDEYCLYC
                     ERYNEKMSEYLQLKKEIQKLEKKVHAWKYKDSRSGYVESQNKPRKKKQAYVLKMVNGE
                     ELIVLAYSEEEVRELVETPVRKKVETINEIDDSQYNSIYIETSHGGYKKLATFLRSSK
                     VGIISKKDISAVTDSFCTLSVPKAYFQYDSKRFERLEKFCRPYTVLKTKKFNKTKRVS
                     IQLPTGQISLGEKDYLIKVGKELIIKVPEHLFKENFEIRETLVWKEEK"
     gene            35453..35635
                     /locus_tag="ACG8LA_000317"
     CDS             35453..35635
                     /locus_tag="ACG8LA_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202653.1"
                     /translation="MAVNKILQVLIIDEFGGGEWFDVQSIDFEEEVVVIENIYGEVYS
                     YSLEGENVEDLRLIGE"
     gene            35825..36112
                     /locus_tag="ACG8LA_000318"
     CDS             35825..36112
                     /locus_tag="ACG8LA_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202654.1"
                     /translation="MVEVEFGSKEWFEELNSMIKFPEKFTFYYNKRDNIIQVALLETK
                     GRLENTRWSMIKPSALRFHPKDLTAVVAVKEVQDSQEYYEVVKNLKDIWCK"
     gene            36203..36442
                     /locus_tag="ACG8LA_000319"
     CDS             36203..36442
                     /locus_tag="ACG8LA_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202655.1"
                     /translation="MKEIEGIKKRNQERLELLNENRNRMFSYYESMRCLNKSRSEIIE
                     SSKYKQLMEERVSLIQEIETESIFPDHSPKVRFYN"
     gene            36570..36899
                     /locus_tag="ACG8LA_000320"
     CDS             36570..36899
                     /locus_tag="ACG8LA_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202656.1"
                     /translation="MKLEGSLQNRMMEGSTTNKEIVVGMGATELLYTDRNPYTVIEVK
                     SKNRILVQADGAINKATFPDQEWEYSRNPEGQILELVKTKNGWKVLKEDIHFYIGDRE
                     KYYDPSF"
     gene            36952..37365
                     /locus_tag="ACG8LA_000321"
     CDS             36952..37365
                     /locus_tag="ACG8LA_000321"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202657.1"
                     /translation="MFSQEEIISKSQPDKNGTIIMKKKIPCYRCSGSGQYKFMSMGKI
                     TYGTCFKCDGDGFLVVTEKSFTPEYRTKLNVLNKKRADRKIRIAREKESQKNFDRYGF
                     EKGYIYVVIEKNSYTIKDELHHQGATYDPLLGWFF"
     gene            37445..37783
                     /locus_tag="ACG8LA_000322"
     CDS             37445..37783
                     /locus_tag="ACG8LA_000322"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202658.1"
                     /translation="MKLEEYSKRQQEILSAKRREEGEFIGTIAQRLELDLKLTNTVTI
                     DTQWGNVYLHLFEDQNHNSLIWKTNKFLYYDEWDVGEIRKVKATIKAHDYYRDTKQTW
                     IKNVKIQKNE"
     gene            37798..38115
                     /locus_tag="ACG8LA_000323"
     CDS             37798..38115
                     /locus_tag="ACG8LA_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202659.1"
                     /translation="MKREEYKQRLNELLEEDETLTHGSPDEILYMIDNMVIFGGYELG
                     NRSVDHNILEFDDVSWEEILDWGILAVPETKTYISDTMVPFFEELDYKRLPKNENHIL
                     GGN"
     gene            38118..38261
                     /locus_tag="ACG8LA_000324"
     CDS             38118..38261
                     /locus_tag="ACG8LA_000324"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202660.1"
                     /translation="MLSDLLILLIYLGGTEIIAYFLLVIGEYGISSAITQRFRLPVSE
                     LKK"
     gene            complement(38465..38941)
                     /locus_tag="ACG8LA_000325"
     CDS             complement(38465..38941)
                     /locus_tag="ACG8LA_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202661.1"
                     /translation="MTDKTSDLPKLDPKISQVKSKKDGKTKNAVKETSSLLLDIPMSS
                     FDEILDANTDETSVKIASHVGMNSQNDYFYNLLNSLRKLEDKKNQVIASKAPDLTTDL
                     DAEIIQIKQDERSVKSLLKTYFDGFDKELAPYSQAILTKPIQAPHISISLQKKSDD"
     gene            39025..40398
                     /locus_tag="ACG8LA_000326"
     CDS             39025..40398
                     /locus_tag="ACG8LA_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HFQ0202662.1"
                     /translation="MKKSKRKIATLLTLMVQFTGIAMSVITINPQVLHADGIATYDAQ
                     FNCTTEGSGSGTDSDGNDTGSGAVTGDVAKNIEDIYKYMNGEYGLSGASIAGILGNWK
                     QESGIDPRTVEGYYGDGQREVDFIKQFTDGLMGIGYGQWTAGRHTALVDWSKKNNGGS
                     WWTTEAQLDFMFKGDGGFVGILKDYALNASDDVVENAVTFHKNWEISADSESAVIAVR
                     GENAKEIWKYMKSKGMDGAKDESKINKISGGSSTGDGSNNSSSSASGTVEDACATTDD
                     ANSGSGSIGKEGKINGKKGQVIANMTYEEALKKYGKAITLPKFKEPDWSTSPFQGELQ
                     GQCTELTWAYMSQLYDGNQPTLGNGGYVWESYKSAGAKVTNKPIVGYAFSALDGWLWA
                     VGSAGHTGVVIAVFDDGSFLCANFNVPPTQAPTRGVSVTLIDGVDGSDNVHFFSGVGK
                     AKFEIEK"
     gene            40423..40950
                     /locus_tag="ACG8LA_000327"
     CDS             40423..40950
                     /locus_tag="ACG8LA_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202663.1"
                     /translation="MNSKTKDAIIISLLSGMLLAMLVGILYFNKQNQDIEAEKHSVQI
                     ENELTFFKEVKPNEVDGLQRDLENDIQEMFKGSDRSKFANQSGEEFLRKLFIVTGKPP
                     VTNESSEQEKIEYYKPFTFKLTNFGIKTSSSGLYEALTDFEVQYNGKKVYDTTLTITL
                     NNDKKVTGGAFYAKS"
     gene            40937..41500
                     /locus_tag="ACG8LA_000328"
     CDS             40937..41500
                     /locus_tag="ACG8LA_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202664.1"
                     /translation="MQNHEITTAKKAIGILSIILILCCVVLFQKKNAYDNNVKELEDL
                     KSKQIEVVKNNQKVKAMQEAQYKELGNAEIKEQSRKFFNLFYNWNSWEKYTKNMKEIQ
                     KEFPQIVKSSPVDISGTMVGTGNSPISSYTADYYTTNQKGKMVELITQTRNTPTTATT
                     TIWRGVTSIGENQLFYLEDLDSYVRAE"
     gene            41918..42655
                     /locus_tag="ACG8LA_000329"
     CDS             41918..42655
                     /locus_tag="ACG8LA_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202665.1"
                     /translation="MADRKLEKLLEETWDPKEFSEFFMENFETDLAVIVKDALREQGY
                     PETANYININFTLYTENRGTWDFWANLANKELSDKSDTGIRNFFESNRDDYMYANNQN
                     KLNFRVEFDETPEEFIERQPPKENVAKVLEDRWNSDEIVSTISEQDGQYEPLVEAVRE
                     ELRLNKFPDVQNIDVSQIEINVNITNRLDYDSWADIALEKYIYSTLKEFIENRMNIMY
                     LQHPQYLNFGVEIATPLEEWKMEQGLD"
     gene            complement(42672..43088)
                     /locus_tag="ACG8LA_000330"
     CDS             complement(42672..43088)
                     /locus_tag="ACG8LA_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202666.1"
                     /translation="MNKKRKLSVLITLVSMLAILSGILSIKIFNQINTSANTKNEIVI
                     ENTSNSKEISTTKNKDKSDETTTKNYLIKTVYFDERKTAILKDEEGSELKLPITVSDK
                     FNGTFSLQTAEGSPDNLKVGQTIILGKDEELYSFVK"
     gene            43481..44728
                     /locus_tag="ACG8LA_000331"
     CDS             43481..44728
                     /locus_tag="ACG8LA_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C39 family peptidase"
                     /protein_id="HFQ0202667.1"
                     /translation="MNMKKNSLAMVLFASAVLAGLSVPVTSHADEWTANTPDQIQITT
                     GQSSYAFKKGDTIWSTVEKLKSLGYKTTVAEFAELNNVDLAKGEQRTIPIGRTFNINK
                     DTLTVKEADGEVVSQTVQKDKPDPVENTEQENKKSETTKESEPTANTSDKTETSASSV
                     DGASSSNTNNSTSEKEASQGTSESSTTEADTGTSTNNSQSTSNDANESTSTSSSDQSQ
                     TGSSDETDSSTSPSNPEQPTNVVLGVPFISQGNTMLCEGTSLLEALHYKGVATNQDLM
                     TFVKSMPLSPDNNPNNGFSGEWRHNVDGTYQGMNPAPVVSWGVANGGNVVDISGSSVQ
                     GLKDEIVNGNPVVAWVTYAFEPAQHKSMFWGDAIWNRHVVAVDGFKDGFYHVVDPVFG
                     ASWINAGSFETAYNVSQLAVSVR"
     gene            44865..45008
                     /locus_tag="ACG8LA_000332"
     CDS             44865..45008
                     /locus_tag="ACG8LA_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202668.1"
                     /translation="MLSTKKVINRCGDFNLGMGAKVITTPTYRGSFSSPNWYKEGVTR
                     DEA"
     gene            44998..47388
                     /locus_tag="ACG8LA_000333"
     CDS             44998..47388
                     /locus_tag="ACG8LA_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaA isopeptide-forming pilin-related protein"
                     /protein_id="HFQ0202669.1"
                     /translation="MKHEKTIILKSKIIYCFATLVMVLSTLIMPFSAIRAEADVTKPT
                     SAKFTETGVKTDGYIRVNMPNHPNEWMISSQFKDSHGNIGYCMDSELPSPTGSGAGSL
                     KYKGAGSDEFYRMFKGGFPSKTAKELGAGNDTEAWYATQLVSWVLAGNFKVSQIVWSH
                     PNHTAAETARVKKAFEKIYDYAKNGKDTPNTEFSITASKTADEGKYHTFTYKTASNKT
                     GNAKLTFTSAKPAGMKIYDADGKEITNNTVKLNSSFTIKVPVTTPSGTLSFKGTANVS
                     TTNPFTFDGRGVYQDAVVMITTSETKDSKSLSAKWTRAVGQVTVKKVDQDGNALKGAE
                     FTLTDNNNAKSVKTTGDDGLATFDLQQGLTYSLEETKVPEGYQGSFKKDGITVNTDGQ
                     EFSYTATNTIKKGKVKVKKVDQDGKPLANAEFTLTDDSSQTQAEKTDENGLASFDIVA
                     NKTYSLEETGVPTGYTGVFKQEGITVKDDGQTFEYTATNTLKKGLVKVHKVDQDGKPL
                     ANAEFTLTDEKGATQVEKTDENGLASFNIVANKTYSLEETGVPVGYTGAFKQEGITVK
                     DDGQTFEYTATNNLKKGVVKVHKVDQDGKPLADAEFTLTDEKGVKEVKKTDATGLATF
                     NIIANKTYNLEETKVPTGYTGAFKQEGITVKDDGQVFEYTAKNTLKKGVIKVHKVDDQ
                     GKALANAEFTLTDDKGVKVVQKTDSNGLATFNIVANKTYKIEETQNPNGYTGKWSKEG
                     ITVADDEQTFEYTVINHLVPETVRTGGIGTSAFLLVFLIAGLSMVLLYYREQHKAK"
     gene            47437..49272
                     /locus_tag="ACG8LA_000334"
     CDS             47437..49272
                     /locus_tag="ACG8LA_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaA isopeptide-forming pilin-related protein"
                     /protein_id="HFQ0202670.1"
                     /translation="MKSKKIFSNLMLFGTLLGVGLGASSISSSLGLGGQVAYAQQNYN
                     YQGTGTIHIHKVTNTNGDGNPVSDIDNKGKEIALPNGVKPLEGVEFSYVKLTKDEAKS
                     LGWTDSDTTKGQHIDDAKARLLLNKKYSEVSRMKTDSQGNIDIPIQVNTDDLTDNLYL
                     IVETGTVKGVVEEAYPMIVNVPELNGSDDQYFNYDVHVYPKNYFQLNSAELDKKDEDG
                     KALAGTVFELRKDDGSDQVVGTYKTDSTGKLTVDGLELGDYYFLETDLGTDANKTTYL
                     LDGKKFKFSVKRGETAKVVLDVTNYKRPVITKVIDKETVDTGEDVQYTLKPSIPGNIG
                     NYEKYVVKDVLGAELTYDSSEVIEGMTLDTDYSIERDGQTTNYVFTESGMDKLQKQFD
                     AGDRFFTILMNAHTNSKAKMDTPLKNDVSTIYNNGYEPEDETPVDHAYTIIGDHQFIK
                     TDGDTSKALSGAKFVVKNKIDPNKVTYLKQDPTTKAVTWIADKSKATEFVSGSDGKFQ
                     IEGLQYTYDVDFDKQGNPTITDKKINDYALEEVVAPSGYTPTRNDVPFVVSNDDASSE
                     VTDIKNLKTPETVRTGGIGTVVFLVVAGVAGTGLYVVYKREQHKA"
     gene            49347..50204
                     /locus_tag="ACG8LA_000335"
     CDS             49347..50204
                     /locus_tag="ACG8LA_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HFQ0202671.1"
                     /translation="MKKKNIKLIILKIGMLLCLGVGLYPVITQAYTYYQTQQTLNSYK
                     EKYDEASEKENEEVFKRYSEVNRKRKDTEQTSVTIPEDNNNIPSNVNLQKDKLGELVG
                     EILIPKINVDLPIYDGVNDFQLSAGAGILTGTDYPTGGIGNHSVISAHSGIPNKKYFT
                     DLELLKLGDKFFIDISGKKLAYQVDRIKTILPTEFEDLLPVAGKDYVTLMTCTPVGDN
                     SHRLLVRGVSIPYQKSIVEKEKKKEDLKVKAQMNWYHIVVVGVLLIIAVIVIIKKIVA
                     KRRGMKNEE"
     gene            50194..51273
                     /locus_tag="ACG8LA_000336"
     CDS             50194..51273
                     /locus_tag="ACG8LA_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HFQ0202672.1"
                     /translation="MKNKILLFLTLICTLVLTIYPANQLYHQFKTKENVAEIQEKIEK
                     KQTPSKEEVAKKVEQIKSNSGNQGLDNTQKTDGGSFDIGEAEGKVNPYTGDVFSKNQT
                     KDFEPSTYSGAVGYVYIPKINVLELLFLGASQEHLYRGVAQMSATSLPLSGKGHQTVI
                     AGHRGGYTSPQFLYVDQLVAGDHIYIDYLGEKAVYTVFRTDVIRNYGQNSTLTDIPDL
                     DMLTLYTCHPYPQNYDRLLVRSLRDEKAKYITPQVTVGNTAYADAIDSESVSDKTETV
                     TSSNDLFEDVDRANKELDGNNDLNIPEQGSVEMQDRTFAEKASSIFTGITNKHQKMLL
                     VIWTVIGALASLKVLILLIKEFRKA"
     gene            51612..52412
                     /locus_tag="ACG8LA_000337"
     CDS             51612..52412
                     /locus_tag="ACG8LA_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202673.1"
                     /translation="MVGISKTALDSLAKLFSSRFDSAEFVEYLSQNESGKTLIETMKK
                     DYLNENDFPTWTNIEDATWDVVCTIYSPWVTIADFVLDKIGGDTYPDAKSLATSDFKT
                     FYGYLIGLIGNGIDLKVTPKQTPEEIEKEKGEVQMAYANDREKVKLLEGKLSEEELGK
                     MVQEINEDSNYFPELKVYQNDEDFFNEMFSNSPWEAVSKTNLGEWNFQDDLVAFSNDG
                     YLRSYSESEYRAELKTYETDILMSYLNLLESGQGELRDKVEELLKEEL"
     gene            52518..53306
                     /locus_tag="ACG8LA_000338"
     CDS             52518..53306
                     /locus_tag="ACG8LA_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202674.1"
                     /translation="MSATTDMALEAVIKDNTGNVENVEDFSDIAINLSAWISAVGEEN
                     IEFEIKNMDDLKAKFPFIASKLSQFAEDKSWNELVSFSEKIYDITQEDECVSWEMNNQ
                     YKKIDAFVKSRIEGTAFEFEGIDTADNWLNKESFIKSIADDLEKQWSKEDYAEYLKTE
                     RDTEVKEKLTEVCLDEHIDPNIVKQEDYEVVIDKVPTDFEEVVKYIVEEALSQYSSDE
                     EVDEETVRTRVWQLVFDDKDYKYLSDQNSVNWSVRLLIDQNDIE"
     gene            53538..54407
                     /locus_tag="ACG8LA_000339"
     CDS             53538..54407
                     /locus_tag="ACG8LA_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HFQ0202675.1"
                     /translation="MKKKKFSRSLLGILVLVAVGLSGKGYFQNNSTQEHDFQIKSSVQ
                     VGNKADSESKEFLGIRYDPNKYPNNIVNINDGKYTLTKEDHEALSEKGSQTFWVNYAD
                     LDQLGRAGDVEALITYDAINSHSSKNVERPSFKSSVHIAGEYKDGVFDQERDTWVGKD
                     SNNEITQLEGYKGYLYNKSHSLAWSLGGDMEVHNLTLGTRAQNVGKNDQNGGMAYSET
                     IVRDAIYKNKNEKVLYKVDPIYKGNELVPRGSHVEAFSVNDNGKTVNLNVYVFNNQKG
                     ININYQNGTWVRD"
     gene            54427..54774
                     /locus_tag="ACG8LA_000340"
     CDS             54427..54774
                     /locus_tag="ACG8LA_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202676.1"
                     /translation="METISINGLDKSVANRIKKGNGYYLLKKGKYSVARELETMSIVY
                     VAKNHFDVEQAIFDPDSEIGKCVELSEKTVSTKGAMIIEREMLDEIRVIIPKDTQMCE
                     DSISDDEPKSERK"
     gene            54787..56049
                     /locus_tag="ACG8LA_000341"
     CDS             54787..56049
                     /locus_tag="ACG8LA_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202677.1"
                     /translation="MSEKSIELKEYKRSDGEKYYPVASFSKSVYLVGRALVVGAIGIY
                     ILHWVTKVVQLLVDTLVSILVSLNDVNGTDDLGLKEMFKELLNAFFPNYLSYSYNVQS
                     FFAKLHLVDISILVLEAGTVFFVGYLVTLMFRHHYGEQRPFFDDMESRRLKREALEAM
                     DVKYDPNKIIGDETNNKKRKRNKTQLESDVLSTLKNIKISVHTRRDLSVNEDIREYIV
                     KIPQPKGKKVRETVLRQIQDLGSILTRATSGRAKFGEKEDEVSGDYFIFRASVNIERE
                     RKERVSTKNKETERATSSIAVSNSQFSFPINLFADNSKNIQNQTEKARKYAETQKQSL
                     ELYLSSADVPASLTDMHVGNTSIEYLFTLSRTRKIQLSSMKEEIETYLHISGVIVRIN
                     AGRIQITLPLGENDRIPIDVPSMINSVF"
     gene            56129..57505
                     /locus_tag="ACG8LA_000342"
     CDS             56129..57505
                     /locus_tag="ACG8LA_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsK/SpoIIIE domain-containing protein"
                     /protein_id="HFQ0202678.1"
                     /translation="MAMKLLEKVKKRAEKAESILLDKEPNIKLNGKFSVNMLNTKAKD
                     PTDAIFGIKPDGTIAHFCISEMPHMLVAGTTGSGKSVLLNEILVTAMCHSTPDELKIG
                     IVDPKRVEFGRYKKLPFMLADPITDMDEAYDFFEYLVILMHERYKLMEKAGLQNITLY
                     NEYAEKNGLDRFPYVILLVDEYSQLVGTHKEVEGLIVQLGQMARAAGIHVILATQSPR
                     STVVTGIIKANFPSRVCLMVASDLESRIVLDEGGGESLSPKGDMLIKLVDGSMVRAQG
                     AYISNKEIETIFNHLRNTMPEPEYVDYRAIVAETRGEGGEDEDFGGIGKAPVRKSAKR
                     NLNTPLANPSSKEPSIEKKSAFAIKLEKNKEEKANQGAKSLEKLQQEKLEKLEKALSS
                     STSETQSSKGIDNGQSITTKNKPKNSNSNLSVNVVITTDKSEKKQVNGTTSPIMQKMI
                     KAKKQVQK"
     gene            57502..58131
                     /locus_tag="ACG8LA_000343"
     CDS             57502..58131
                     /locus_tag="ACG8LA_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202679.1"
                     /translation="MIIISSFLRWLTPYKYTDEIVEKRAKKKVKKTMLTPKEMLDRGI
                     LGVKVLEVNQPFELDNARDRLLRAEVDVAYFYHDKSKHQIAIKFNPKSAWRYQARDDL
                     KRRKLKPMLYPEGKEAFDRTHIVPIGFHGTESDNRLLVGWNSSQNRVQINKFEKKVRK
                     FNDRKIILWFANIQKQPDGTAKWEAVIFDEDGKKVMSEVWHDKAKFVWQ"
     gene            58143..58613
                     /locus_tag="ACG8LA_000344"
     CDS             58143..58613
                     /locus_tag="ACG8LA_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202680.1"
                     /translation="MLTNLKLYREGFNEKVSIGESIEYLGKKYIIIRILEIKKLYFSK
                     YNNLAVRVLVQKVGNPSDYRSDYHNYKTESSVIKRYNQSKNDERIFKVGEIIISKYGI
                     AYEIVSIKKFYYEFVDLVVEYSVRLIVPWSKEEINEALKHERKSTFKVLEGEKK"
     gene            58610..59092
                     /locus_tag="ACG8LA_000345"
     CDS             58610..59092
                     /locus_tag="ACG8LA_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002389003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202681.1"
                     /translation="MKTDLTRQAEKCLWHETNRMGVFGCFEVTIGWDGSERVDYITYS
                     VDNTVRCYEIKVTLADLKSKAKQTFIGDYNYLVVTSDLWEKMQQDDKLMRKYYYQGVY
                     VFNEKYPSIISVKKARKQKVSLGTRSTVLESMVRSMNREVKKLYKVKPFWEIAEVEKG
                     "
     gene            59089..59751
                     /locus_tag="ACG8LA_000346"
     CDS             59089..59751
                     /locus_tag="ACG8LA_000346"
                     /inference="COORDINATES: protein motif:HMM:NF019467.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HFQ0202682.1"
                     /translation="MIQTFAKMSRSAWIEKLENDLSVMRLAPKKFKREIAEKEAILSV
                     LNAVELDEPKKSVDVPENVAELLDYYRNSSDVDLLALILTFHDWYYCQNEDTQHDKHD
                     KAVDWLIENPEKFMRAWLDGYDSKKKPLESNEETYLTAEQYDYARKTGDWESGKTFNH
                     RKDQPKISFSDIAAIIEGIYYGQADEEIFSIQDLLEFLNKNKDSFVELTDYEEDTANG
                     KL"
     gene            59738..60106
                     /locus_tag="ACG8LA_000347"
     CDS             59738..60106
                     /locus_tag="ACG8LA_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5406 family protein"
                     /protein_id="HFQ0202683.1"
                     /translation="MENYDPNMRWGTHTLKVSFQRWDYKGFVTFRKAGNCKGLDVLAL
                     DEDYLYDHPLTDNPIGFGLLPEDDEGNEWFKMILTNDKGDQLFVEDTWSYLSEYIVSI
                     KIIDFVADKEKEIGEGKSNY"
     gene            60187..60633
                     /locus_tag="ACG8LA_000348"
     CDS             60187..60633
                     /locus_tag="ACG8LA_000348"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202684.1"
                     /translation="MIVSAVTIYWLGNQQNSLIVDLGELKVGLRMTRWLLLAQTVGLA
                     ILTWICVEKITSNNNQEIVESTNLRITEQAIEKQKDKEKKEIMSIYLSSGASFFHEID
                     SMKLSSQEIIDRWKNMPLGGELIVEDSDGWSAYKKDEIVAITILFE"
     gene            61342..61941
                     /locus_tag="ACG8LA_000349"
     CDS             61342..61941
                     /locus_tag="ACG8LA_000349"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HFQ0202685.1"
                     /translation="MREKNKNSSRYLVATVVFVCVLIFLFDFLQIGKSIIGNTLSAKE
                     MVALGGLYEGHLFPNIFISIVSHINLYHLISNLLFLVVLEEALNDQYEWLTLLIVLII
                     SGFLGSLVPFLLQSNIVSMGLSGGIFGWIALFAIAYIHFDSKEHLLLSVFVLLIIGIL
                     LVSTFESGEANVLSHVIGFVCGMILGFILKNVSLIKQKN"
     gene            61957..62433
                     /locus_tag="ACG8LA_000350"
     CDS             61957..62433
                     /locus_tag="ACG8LA_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202686.1"
                     /translation="MPKRKEKKIPVFLSVSEMLSLQILLRKKIETIDEEVRNKRAMYE
                     QREALRERIHYFDDIHTKIYEARTNHEDESKLGLAQQRILEWLNTNTDQEPLRVISNL
                     FEFGTKHWFNAVEKDADLQEAFDTLSKDSKSMRDLLITYLNEHEFEQTKTKKKNKE"
     gene            62450..63352
                     /locus_tag="ACG8LA_000351"
     CDS             62450..63352
                     /locus_tag="ACG8LA_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202687.1"
                     /translation="MLLTLLGYLCLILAFFGAIAIIIGQFQTNNPIMRNIGIGIVIVT
                     FIVFNATKIFGSNDKQFGISGVNNSYAPDSLGRVVIDGTFENVTSYKNVSLTVKEDGK
                     KASDDVLATIKPSQSQFEVFYTVKENSPVHKLTLVFNVDGEEYYKDVKINKTSTKKII
                     ESAKKEVATEESTTESSSTVEAELPDKIDFDPEKVKSFESVSGSMADRFNTEVFKAIK
                     TVKLDTEKQMINVTLFNSVESMDQDKKVTVARELGKRVIGLYRGTAKPDSDGADLPVH
                     VVYEDGKVFGDSTANEALTIKLAK"
     gene            63425..63616
                     /locus_tag="ACG8LA_000352"
     CDS             63425..63616
                     /locus_tag="ACG8LA_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202688.1"
                     /translation="MVVNKEKVRKYVTLKIASVKYLEKRAKEEERARGKKVTVSELLE
                     ELIENDQTIRRAFTNRSIR"
     gene            63780..64367
                     /locus_tag="ACG8LA_000353"
     CDS             63780..64367
                     /locus_tag="ACG8LA_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202689.1"
                     /translation="MENNNDIRHFSIGERVTTVSELSKDYRDKEGTIISLNKNRRGVW
                     QYVVDLGDGVTVECKDSQLIRNNGSHSIEKAILVYPKVSSKIMNDWLLGKFGEYNKKE
                     IAEVIGKSYPTVLGYLKKITSKEAKIEDVLTVRELQSLIEYRNKQITNPEYLRKEDGL
                     LKQLEQVNKIRKMQKVAPLSLDTFKKIYLKEIKKD"
     gene            64367..65266
                     /locus_tag="ACG8LA_000354"
     CDS             64367..65266
                     /locus_tag="ACG8LA_000354"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0000400 - four-way junction DNA binding
                     [Evidence IEA];
                     GO_function: GO:0008821 - crossover junction DNA
                     endonuclease activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HFQ0202690.1"
                     /translation="MWTVTLPFQPVSAPRPSARRNAADETNDVAEKRISTYYDKKYLD
                     YLKKIKSFIEDQDLLDDEFYSIVNDPMGAIMEVDFYYQIPKSYKKVYNIMKTTAPDLD
                     NLVKSAMDGIFNISAIRDSHITGLIAFKYNVANEGKTVVRIKRYSEFEWDTSEGLNGD
                     IWEATFDFKPVATPRPKSKFRGNGIITYYPKEYNDYLENIKNTLKEKDLVNDQLKKVM
                     NAPMGVIAQIDYFYQVRKDKKKLDSLMRTSQPDIDNLVKGTLDGIFNKEIGIKDSRVV
                     GLIAFKYNTFEKSKTNVRLQEMG"
     gene            65266..66180
                     /locus_tag="ACG8LA_000355"
     CDS             65266..66180
                     /locus_tag="ACG8LA_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202691.1"
                     /translation="MNNNEKILHVLDSFEIIQEELKKYRDVLEQRYDFVNQQKSNHMD
                     FILNMNDLKKKLVERKEQEKLIKAYFELGEKEVKNAMELNEERRVLDQLLEQLLVMFQ
                     KGRIDEDLIEEGLRKYPSNSGIGIVLKAIDEEEIEAFIPPEDFESAMEYIKYYSQGIT
                     AFREFDPEDVIHDLNNLKEWCESYGVDDSGLDYLISIMEIEEEMPDKPDPTDILELIH
                     EARNPIAYISRGYTVLEYYKPYISAMNHLRRVLREKREYRSVLNATNRLEKAVSELDA
                     YYREHYLQAGGMPRNTKANISRYIKKAE"
     gene            66232..66447
                     /locus_tag="ACG8LA_000356"
     CDS             66232..66447
                     /locus_tag="ACG8LA_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202692.1"
                     /translation="MKRDVFELYVLERLEDGMMAQEIIDEIDDMISRFGQLELNDGNK
                     NSVVLKQFWLNNFSYKDFIKEKANTLY"
     gene            66633..66887
                     /locus_tag="ACG8LA_000357"
     CDS             66633..66887
                     /locus_tag="ACG8LA_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202693.1"
                     /translation="MKKEELIDIFQIVERANNMGIMFFDRISLKMDLSVAHQEFNLRL
                     KALLNSDDVNFAHDVVGIQNHIDRENKRMGDEFLPRYSSL"
     gene            67066..68109
                     /locus_tag="ACG8LA_000358"
     CDS             67066..68109
                     /locus_tag="ACG8LA_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C39 family peptidase"
                     /protein_id="HFQ0202694.1"
                     /translation="MKKFLVGILFTMGLVLLSPSVSAESSISMYRMYNPNSGEHLYTR
                     SVGERDNLKRYGWHYEGVAWQAPTSGTPVYRLYNRYNGEHFYTVDAGERDKISHTGWT
                     YEGVAFYSYNGANRVPVTRLYNKYVNWHHYTLDQNEKNVISKQGWKIEGTGWYAMPNS
                     VPNPTPAPSTEKVLNVPVVWQGNTMLCEGASLLEGLHYKGVATNQSLTSFVNYMPKAN
                     DNNPYHGYSGEWRHNVNGTYQGMMADPVVKWAKNVGGNAVNITGSGTNGIKNEIRNGN
                     PVVTWITYNYATPEFKQMPWGRAVWNGHVVLVDGFRNGAYHVVDPVFGAKWINASTYE
                     RAFNVTGMAVAVR"
     gene            68282..68506
                     /locus_tag="ACG8LA_000359"
     CDS             68282..68506
                     /locus_tag="ACG8LA_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202695.1"
                     /translation="MNQRRRKRLEEISERLSELKDELEVIQEEEYKENIPKNLQGSER
                     YEKAEESVDQLEEAVDGLSDILELIEDIAS"
     gene            68509..68766
                     /locus_tag="ACG8LA_000360"
     CDS             68509..68766
                     /locus_tag="ACG8LA_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202696.1"
                     /translation="MINEDFRSENKMIDISLIEKLLFSNKYTAKELATRWQISESAIK
                     AYRQNKGSVGWRDWKGISIGKAEDIMKREGLRSYTTSEKDK"
     gene            68868..69221
                     /locus_tag="ACG8LA_000361"
     CDS             68868..69221
                     /locus_tag="ACG8LA_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202697.1"
                     /translation="MISENLSYENNKHLVKENKKVEDYKNMYIEMKKSPLCIQYKNDN
                     WKQVVEFVKPHSIRRVRRGKKKSELVNSGRAVIRVITKDYPVEYGDYILRLSYHAFVV
                     LKEEHFNEFFNLKSK"
     gene            69274..70068
                     /locus_tag="ACG8LA_000362"
     CDS             69274..70068
                     /locus_tag="ACG8LA_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202698.1"
                     /translation="MVAKKNTLKEASEKYQDMKRRGLIPKDKKGIWREFVKEVSSDRS
                     GGDFVGRYTAKGYSKRLRITVEYGTNESATELKQRYLDTRREASKKYNDFKSRGLIPK
                     KKKGIWREFFKEEDSNRNKGDFIGRYTAKGYTKNLGIKVEYGTGESSWELRNRYLNTL
                     LEKYKAELLELFDVNDFIEMAEKYGHEEGFMINDIMVIDNFTDLLALAKKARDLRETQ
                     MYLFRNKNGRNRRTESSEIEDYYDAFTHDLGAFVDEISGVMNKYRV"
     gene            70097..71215
                     /locus_tag="ACG8LA_000363"
     CDS             70097..71215
                     /locus_tag="ACG8LA_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202699.1"
                     /translation="MGNNSIYTPEMQNKIKRLVGLGWMTRGKLDSFSTIKYLLMDIYR
                     QNKQTGIHFLGYDKPEDAPFFVPSSAYRASTSGSMYNLDLFEEGAKMIEYDFNEAYSR
                     IMRNYPLPSNTYLKAKYNTDQAILRAINRPKVRPYENLRTYMFFLVNFEGTAKEGTYA
                     NPKSQSMFADYGENPKTANEPIWLSEIELTLILDYYDIKEMEVLDSHTFLTKKGLLKE
                     YFERIEPLKTDPDTLKLYKNLRTKVFGAIGQKSLREGETSTFDKYSMYNRAYSSMVAG
                     VFRDRMVRYEQKYVHSAYGLLKIRTDGLYFRSEVPEFEELYKLGVVKKKVHTISKEEV
                     EKALEFKNKGFENKGSFGKSKDEVKGVVIDDDFEFDFD"
     gene            71248..71568
                     /locus_tag="ACG8LA_000364"
     CDS             71248..71568
                     /locus_tag="ACG8LA_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202700.1"
                     /translation="MKKKIVEGNVGVIILKDSTDYAKSMALKDEKVARMDKDLVEFLM
                     DDTERLKGDQFLSLMKDKGLNTYGLFDYKKLAIEWVKEGEIFFIEEWEGTENLVLHQY
                     LLKA"
     gene            71823..72512
                     /locus_tag="ACG8LA_000365"
     CDS             71823..72512
                     /locus_tag="ACG8LA_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum ABC transporter ATP-binding protein"
                     /protein_id="HFQ0202701.1"
                     /translation="MRTHYIYLEDKIVDEIPAKSREQARKLFIEKYKEINGDSEVPKV
                     VVTVRKRQTKKRSTFHVSPDIYNLIERHRSEDNISISQYIATVIDELISGKYDYAFDF
                     EGEKDYKSVAVFQSDFEKLKNYAGRRNVNFARLLEEFYSEELGVGNEYKRETYAKLSH
                     KLSQALKEVTEVKAELDAKLEEVKKYQTERKNNMKNQVEFDEQKEFEKARKRYNKIMN
                     ELSYEHLTVHE"
     gene            72549..72716
                     /locus_tag="ACG8LA_000366"
     CDS             72549..72716
                     /locus_tag="ACG8LA_000366"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202702.1"
                     /translation="MVNEVETLLASFFENGHVNDEWRKEEPKRVNAYIARLKRFIDKY
                     KENSDKFSKDK"
     gene            72736..74364
                     /locus_tag="ACG8LA_000367"
     CDS             72736..74364
                     /locus_tag="ACG8LA_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202703.1"
                     /translation="MPEIEGIFSPKIGKKQLDFSSFPSVNRDYNLGDEVQILNIDFKE
                     LDFAVAVSNKPKALERVKKIYQENDQNIKNMIKKYRRDNSKVEDVLFNGTAKHDLNVY
                     MALGVALYCNSINQTDILVNIVRNSYQKILKISSETNPYYAMKYLGDNLLNDKKLMHN
                     TEELLSNLAAINFLFKTGSEDYFIDNVLKGAYGTAFYPLYNMKQHKAEQKDNKLEIKK
                     MKELLGIGFVKPNSKVTIASLATTNNDGKIVNGFDDSDIDILSKSYFSLYGDFADLMG
                     IDSYLVNNFEIKGSELNDIVYFVLISLYAIDQNTEYRQIDYLLVFYSLLYQFVLTRLF
                     KNAKEELILNSDYEIAKQIASIRKENKSEVIKLRKELSIASKENGRLESLVKSAKKEE
                     ELLKQEIKELKGIRKELEQLRFENKVLKQLQEQEHRQSLNGKTEEPSLSEMIAYLKHK
                     NILLVGGHVNFQNKLTELLPNIKMFDVSENNGKILKNLNTCDAIFLYTDYLNHGLYYR
                     VMSEISNKDKIFYLDNHVNMNLTIKRIYDLLSLI"
     gene            74415..74786
                     /locus_tag="ACG8LA_000368"
     CDS             74415..74786
                     /locus_tag="ACG8LA_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202704.1"
                     /translation="MRELTLSSKELEKKTALLNEIFSADCIIQSLKESSFSKLTDQEK
                     ISYMLSLDNLGTKYDESASSDKLLIELVSSLSSFGKMKRFNVILEIFAWLIPSFIWFF
                     YIFIVESELIAKVSLGLLIPI"
     gene            74871..75071
                     /locus_tag="ACG8LA_000369"
     CDS             74871..75071
                     /locus_tag="ACG8LA_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202705.1"
                     /translation="MLKRIAWDKDNKTDIELKEYKYNYFSRCIDRKLLFKKEGLEFSF
                     DEDEFEKLVMDWRKNLLDTVQF"
     gene            75205..76431
                     /locus_tag="ACG8LA_000370"
     CDS             75205..76431
                     /locus_tag="ACG8LA_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202706.1"
                     /translation="MIFYMFININEVLKLTTITMTKKIEVYVDGSQEERDSFFDFFWK
                     NSREYVKALNLVYKQLMFEELIKDAIKEMDQGYAEREESIQNRIEKLAYTDPIDQKKL
                     DKAKAELSKLRNEKNKEAREILTQAIGLKSQTRTRDVAKKLDFDFGDFVDSANMKASK
                     DFGNDFIGIVTGQRTPRIYKNRNKYGLLPFRGRDIKIHKDDKFYIYLPKGFRFKVNLG
                     SKPRKARDVASVLQHIMDGDYKLNQSNLIFDGRKLFFNLTISFEKSYNEMEFKKGNEL
                     IVNFADLCSGECLINDKSVMSFGDSQYIRNFKSKILAMKSKEQSRGVFSKGGHGRKRK
                     LDQDRWEAIKKRESNFVKTYNNQCSAKIVKTAIRNKAQIIRIIEPDKAYGEWAYYQLK
                     EQLVNKGKRYGIEVRS"
     gene            77028..77422
                     /locus_tag="ACG8LA_000371"
                     /pseudo
     CDS             77028..77422
                     /locus_tag="ACG8LA_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion protein ImpB"
BASE COUNT        28821 a        10712 c        14918 g        22997 t
ORIGIN      
        1 gattcatcgt cattcctcct gctatctttt tctattattc taccttattt gatagtagat
       61 ttaaaacttt gcaacagaac catctaactc atagctacca gctttctctc cattaaaaat
      121 ttccttagca ctttcttcta aagaatcaaa atatttttcg acagcaacct ttgaagcttt
      181 tactattgaa gcatttccct tttcgataaa atctgctttt gttttaccga caataagtaa
      241 ttcttgatca gtaaaatctt ctaaaataat agtagtgtaa ttcttatttc ttctcaatcg
      301 catcaggatc actccttaat ataatttatg cttttataat atcataataa gataaatttg
      361 caagtgttta tttacacctt tttatttaca ctttattgta attgattata cttttttgat
      421 tgcatttttt tcttataaac agttgcaact attagtaaat aggtgtaaac tattttcgta
      481 ccgaaatacc ataaacacaa acagaaagag gtcataccat gaaagaacca ttattgtttt
      541 ccgttgactt agggaataaa tcagtaaaag aaatgagtac acacgtttct ccactctcgc
      601 ttccctctcg tattttgaac aaaaatatca ttaattcagg acgtttttct aatataggtt
      661 cctcattaaa acgatcacta aacgtttctg aatatagcct agtaaacact actgaaagct
      721 attattttgg gaaggatata cacgagctag gaaaagatga ctacgtgata gaatcactag
      781 gttttgggat cagcagatac aagcaggaaa cctaccaaga tatcctatct ttctctttag
      841 ctaacctagc acgtttagaa gatcaatctg atgacgtttt aaccgttaat ctagttttag
      901 gtctgccttc atccgactat accgaaacaa tcgtcaaata cgtgatgcaa caagccacac
      961 gacaacattc agttgaagtt gacggtaaag cttataatat aaacgtagat accgtttggg
     1021 tactgccaca gccgattgga acactatata acctcctcct tgctgatgat ggtagtgtac
     1081 aagatgaatc attgatcagt cagaagatcg gttttgttga tattggtggt ggcacgaaac
     1141 tttttgatgt tgtccaaaat tttgaaattg acgaaaacaa ccgtgaacaa aaggataccg
     1201 gtatttttac tttatataat cgtatcgtaa atatgcttga ccttccgatc agtcctaatg
     1261 ctttccaact tgaaaagatt atccgagaag gcaaagaaaa aggcgtatat ctatttaaac
     1321 caagcggaaa tgaaagtttt gatatttcag aagtagttga aagagaaata aaaacataca
     1381 ccaatatggt tgttgcagaa gttttagcta cattcaaaaa cttcacaacc ttagataaag
     1441 ttgtctttac tggtggtggg gcttctatta tcgacaaaca acttgtaaaa gataaaattc
     1501 cgcatacctt gtttgttgaa gacagtgaat tttctaatgt aaaaggcttt tacaagtttg
     1561 gtttaactca ataaaacagc gaaggagatc aacatgaata agggaaaatc agagcgttat
     1621 gtagttataa tcaatagaga aaaggttagc gagttacctt tagcagagtt tcttgaatct
     1681 gaatatgaaa cactaggcgt taaatactct cagacgatca aaaaagcttt gaatctatat
     1741 cggcgtgtaa agaacaatga agttacaatt attgaagcag gcaacgatag aaacgatagc
     1801 aaagtagctg aagtaaagaa taaaccaact gatcataacc ctattcaaca agcgcatcct
     1861 tcaacggtta catccgatca ttcagcaaag aaagaaaagc caatgctaaa agggttcaat
     1921 gcaccaagta acaaagactt actttaaaaa taaaaaggcg aggttacaat acctagcctt
     1981 tttattatgt acaaatacaa acataaacat atacgtatac atgtatataa acatgtatac
     2041 gtatatatcc ataaacacgt atacgaaatt tagttaagct atacctaacc gcttattcca
     2101 ataaaaaaag tgatcagctt taaactgatc actcaccaaa aacttcatca tacaagttat
     2161 ctatcatttc accaagtaaa gctgaatctg atcgaattcc taacttttcg ctgattttag
     2221 atagtttctt tctttgtgat ggttgaagcg tgaattgata atttttcttc ttttcagaac
     2281 tatcactttt tagtttagct accaaagaac ttgttgtttc tttaggtgtt tgtttaggtt
     2341 cttcaactgc ttcaaccact tcaggaactt cttctacttc agcttcagcg aattttttaa
     2401 atctattttc tttcacttca atcactcctt attcttgtgc cgtatcaatt attttgttgt
     2461 atagcgtaaa cgtgctttca aagaaatcct tattcttacg atagatattc ttatccttag
     2521 cgaactcagc aatattctta ccttctaagc tagttgcatt aagcaattcc ttctcttgta
     2581 catatccaag ataattagat aacgttggta ccaattctag gaactcacga cttgaattag
     2641 tattatgttt gatcctgcta ccgatcgtag cgtatttagt ttccatcagt gtttcaccag
     2701 tcttaatatc aatcaactgt tttgctagtg catcaatatc tttaccaagc ttaagcaaag
     2761 cttcaaaacc atctttagat ggatcagaaa tgcctacgac aagatcagat acagcccaag
     2821 cattttgagc tagtagacct gcatcattat gagtatcaat cagaattaga tcatacttct
     2881 ctttaagctg ttcatagtta acaacgatcc atctaaacag tagggttctg ttgttaggca
     2941 tatcacgcat ttgcatctca acttgtttta aatcttcacc tgctactaaa atatccatgt
     3001 tctcatttat agctaaaggt tcagctgatc catgaagata taaatgattg attgtattct
     3061 ctcttttcgc tttactgaaa gcatcaggaa atcgttttga taggttttgc gacttatctt
     3121 catcaatata cagcaccttc atacctaaat tttcgacagc atatccacct agattgtaga
     3181 ttgttgttgt tttacctgtt ccaccttttt caatgtttcc agtaatgatt gacaacttct
     3241 tttccatgat taaacctccc ttattaatct tttgtaactc cattatacac tataaacacg
     3301 tttatgtata tatttatata cataaacgtg tttatattta tatttgcttt tatattctac
     3361 aacataaaca tatatatgta tatgtttatg tttatgtata tattcaaata tataactatt
     3421 gcatttgtca tacaatcgta gtacaatgta attgaaaagg agttgataaa ctatgccagt
     3481 aataagtatt cgtgtatcta aagaagaaaa agattttctt gaaaaagttg ctgaattcaa
     3541 cggagataac atttctgaat ttatgcgtag taattccctg caaacagcag aaacgttagt
     3601 agactttgcc acctacaagc aactaatgaa agagcatgag gaaaacgatc aaagtatttc
     3661 ccacgaagat atgctaaaag agttaggctt ataagatgac ttaccaagta agatatgaac
     3721 gtgaagctca aaaagcgcta aaaaaaatgg ataagtttca ggcaaaggtt atcctaaact
     3781 ggatcgagaa aaatcttgta ggcactgatg atccaagaaa gcatggtaaa ggtctaacag
     3841 ctaataaatc aggctactgg cgatataggg taggtgcata ccgtataata gctgatatta
     3901 gcgagcatga agtgacaatt cttatattgt ctattggtca cagaagtgaa gtttataagt
     3961 aacagacaag ctgataaggc ttgtctgttt ttttgttaac ccaacaaaat cactgtttac
     4021 gatcccactt tacctaaaaa agaacaatat cctcttgata ttatacacac cagtgtgtat
     4081 aatataagtg taaacaagct aattaacttt caaaaggagc gattttttat gggatggtat
     4141 ggtgattatt catcagcaaa tgaagtgatc gaagaaaaga aagggtacgc caaaaatggt
     4201 ttggaaatcg taggtaccaa agtaacgaag acctatggaa ttatcctttt caaagatgca
     4261 gaaggaacct acgatattga cagcttcatc tttcgagatg aaatgtacaa accaatctac
     4321 ttcttaaatg acagtcctgc ttactttaag aaaattccga aaaaatggtt gaaattcttt
     4381 gtcggtgatc aagaaaaaat ggttaagcta caactagata gaattaaaga agaaagcaat
     4441 aaaccaaaac ttgatgactt attagttgca ggtaaaactt actcaatctg ggatggatcg
     4501 tatgtcgctg tctatcagta taaactcaaa cgtagcttta tttttcgact acaagatgga
     4561 tcactcactc ggttcactcg actatcagca ggagatgtta aggaagtaac ctaaaactta
     4621 aatacataaa cataaacgtg tatacgttta tgtttatgta tatgtatatg aatataaacg
     4681 tattaggtac gaacactttt aaattctttt ctgggctttg tttttagggt agggctaaaa
     4741 aaaacatcac catctgatcc aaaacagctc agaaacgcat ttaaacgtat ctgataccaa
     4801 tattacagaa ggagtgtatc gtatgattaa cctatttctt ttagtgacag ctagtacatt
     4861 attctttact ggaatatcac tgataatttc ctatttgatc tataagaaag ccgaaaatca
     4921 cacaagcaaa gcaatcggac tagccgtttc atccttttta actttgctga ctttatttgt
     4981 tactttatcg ttttcttttg tttagaacag ctgatccatt agcacctttt tctctttaca
     5041 ttatacacac tgttgtgtat aatgtatttg taaacaagct aattaacttt taggaaggag
     5101 tgacaagatg ctaacagcta ctttacagca acctactcac gttgctattg cagaaagtta
     5161 tacaattaat gcagggatcg ttaaacagct gatcaaggat cgagaattca aaaagtttaa
     5221 cagtcggcaa gcgtataaca gacagctaaa gaaagctatt ctaaagcaca aagattcctt
     5281 catcgggaac ttggaaagtg tagatgttaa aactgtttca acggcatttt cagttgttga
     5341 agtgactatt gacggtcgct tgatttctct atttgctttt ggaattaatt gatagggagt
     5401 gtgaactttg gaaggtaaga cttttgcaga aatttggact gaatttattg aggtaccaac
     5461 tcgcattgat ccgataactt ctgaaaaggt attggatgca gacttctaca atctcaaagc
     5521 aggtactagc cttgaatgcg tttggatgta tttagaagag catttcaaag gcgtaacgct
     5581 cggtcacgtc ttataccaca atggtgccga gtgggatgca attggaaata tccatttttc
     5641 ttaatataag aaaggagaac acaatatgaa ttataccgat gaagaacaaa tcgctttgga
     5701 atacgttttc acaaatgaag aaggggagga aattgaaaaa gtcttgatca tttcatcaaa
     5761 agacttggag aaggctttgg cttatgaacc atacgaatca accgtaactg tcattgaatt
     5821 cttagatacc tatacttcta atgatacttg ggaaattatg aatatttgca acgctaataa
     5881 cattcaattt gctgaaaaaa ccaataaatc attttattag ttttgcaata aaacatcctc
     5941 tttttctatt gattccatac acaacaatgt gtataataga ttttgtaaag ggagggtagc
     6001 tatgcctaag acagcaagag aaattgtaaa aattctcaaa tctaacggct tcaaaaagac
     6061 tggacaaact ggcagtcatg caaaatttta taattccaag actaaaagaa cggtcgttgt
     6121 tccgatccac aatggtgatg taccactagg aacagaagct aatatctgga agcaagcagg
     6181 gctttaacag ccttgccttc ctatttggta ttaggcatac tatcctctct tacactagaa
     6241 aaggagcgag gaaatgaaga caaaaaatat tttttatccg gcaatcttcg agaaagaagg
     6301 agaagcttat aacatcgttt tccctgactt accggaaata tctacctttg gaaatagtct
     6361 tgaagaagca tatttaaacg ctaaggatgc tttaggatta gcgctatata gtgtaccaga
     6421 tgcagaattt cctaaaccat cagcagtgga agaattaact ttgaaagcca accaagtggt
     6481 agtaatcatc caactaaaca ttaaactttt ccgaagaagc ttaaatacaa aaacaattag
     6541 aaaaaatgtt agtgttccgg aatggttagt tcttttaggg aaggagaaaa acataaactt
     6601 ctctcaacta cttcaaaaag cactagaaga agagttgctt gaaaagtaaa aaggagaccg
     6661 aacctatgaa agctacacac ttaaactatt tctctcgaac gttaatcaat aatctattaa
     6721 aagatacaac tggcattagc gttagtacca aacactttgc caatgatcta attatttttg
     6781 aggataataa cttgcgaatt gagatgttta ttgaacaggc aacccctaac tcaatacctg
     6841 aattctgcta tacgcacact gaaaaaatga aacatgcaaa atcagttaaa gatgttgaag
     6901 cattaagtga atcactaacg aacgctttaa acctcgttaa gaaggcaaaa ttgttatttg
     6961 aatttcaaac cgactaccac aatgagttgc ttgctcaatc tgaaatttta gattaattga
     7021 aacaggagaa gagaaagatg aaacaaacac aaacagaaac cgttaacgat acgcttgctg
     7081 atcaattagc aggttattat aaattatttg agatgggtaa agcacagcgc ttgatccact
     7141 atctttggaa atacaaaatt ttgtttcttt tttgggaatc aacactaaca ttctcagttc
     7201 ttttttataa gtcagatttt tataatcaac acttagtttt agggagtttt ttgcttatct
     7261 acaccatttt gatgcttaat ttatatacct acatcacact tgaagaacac ttagtaatta
     7321 gcgatgcagg gatcgagaga aacatcaaaa gggtatcctt caagatcacg ttaaacaagc
     7381 ctaccgataa aaagctctca gaagcgttct gagagctttt gacattttct tgtataattt
     7441 tatcctaaca cattacaaag cacctaattc gagcttatat caagcaaatt tgctatttat
     7501 tactcaatac atatctaaaa attacttgat ggaaaattag atacatggta agcatgaaaa
     7561 gaaaatcaat ttgagcagat gcagtacaat acatagcaat ttaaaagctc tcagaaggct
     7621 tctgagagct tttaatatat tctttgataa tttgtctttc ttaaatccat acgtcctaaa
     7681 acaagctgtt tttgcttaat atgatcatct gagagacatc aaatcaactt ttctctcaac
     7741 aaatcattca aagctttcga cagattaata ttctcttcag ccgctaaaac atttaaatag
     7801 tgttccacag tcactgattt tcgatcataa ttttgcttgt ttcgagcttt agcaactttc
     7861 gtattagctt ttacgacaaa taaattaaca ttctcagatc gcttgattct tgcatttaac
     7921 tcttgaacag gcgtaggcga tggaatttct ttttcttgca actctaaaag caccaagtat
     7981 ccttccaata cttcttgcgc catctcaaaa gcatcttcta aagtttcacc atgtgtatat
     8041 aagtctggaa aatctgggaa tttaactgca tattcatttc ctttccattc gaatactgca
     8101 caaaaaaagt atttcatcgc attgcacctc tctaattaaa aaataatttt tgcttttttg
     8161 tttcaaaaaa aagaatcgcc taccaaaaaa attgataggc gatcacaagc taattaacct
     8221 ctaaaggaga ttaatacctt gctcccaagg cactatatat cttagcatac gtctgaagca
     8281 tcttcaaacg agtaagatat attttgcatt aacctaattt tttttctcta taagtttttt
     8341 catcaaactc actagaaata ttaaactgga cagcaaaatt gtaatttctg ccttttctaa
     8401 ctttagcaaa atcaatattc agcattgatt tttcattaat ttcctcaact gattccctta
     8461 aaacacgtct atcaaaattc gatattgttt tatactcatt ttctgttttc gtaatctcac
     8521 gaattttaac tatttcaatc aggggattct tatatatttc agctttctca aaatctcctt
     8581 tatttttggc gataagatat tttttataat acatcgccaa atatttgtat aacacgatgc
     8641 tatatttttt ttgaaaagat gctaagtctt caaaaacaaa gaacggatac ttctttttga
     8701 ttgagacaat taagggaatt acatcttctg aaaaactgaa agatacacta tgctcttcta
     8761 aatcccaatg aatccgatca atagcagata cagtagtata cgtcttatat tttttgtcta
     8821 gattcgaaat ttcataaact gcttgtcttt gcaaagtgtt aactatggtt tttagttccg
     8881 tttcaagatt ttgatcaaca tccatgtaat taataatcgc tttaacaggt aaatctacta
     8941 cgcctgtttt ctttagcttt gtgggtgaga tataactgaa cagcaattga taaagttcat
     9001 acgactttaa atccattttc atgtcaattg ttgctaagaa ctcctcattg tactttgtca
     9061 gttcatcttt tttcaaaagt ttttccttcc ttcacgcatt ttttcagttg ttaatcataa
     9121 aggttcacat aaggcaaata actcgtaatt gatttttcga gatatttaac agtatttttt
     9181 attgtgtaat cctccttatg agtagcaacg taagataggt gattgacaac tgattcaaat
     9241 cctctatctt tggataaacg atcataaagc ggataaactt tattctgaag tcggctcata
     9301 agtttaagat cgcataagtc ggcagaactg atcaaaaagt ttttgattag taatttagtg
     9361 tatttgctat tcatagcttt caagtacgat tgattcattt tctctgtttt atcttctgcg
     9421 ccttttaaat aagcagggtc tctttgttct tgcttataag gtaccggaac tgacatggta
     9481 cgtgtaagca agaactttat gtttgtataa gtatgaccct tcttgataag ctcatagtca
     9541 attttaaaat cagtgtattt attcagttgg gcaatcggtt ctttaattac acgtctttca
     9601 aagtctcgaa aagctttata ttttttctca atactaaatt tctttcgtaa atctgcaatg
     9661 gagaaaacag gattttttaa tctatcaagt gattttgtac tccatgttaa gttatctcta
     9721 tttgcttcat acagattaaa atctttagtg aataattaaa aaaaactgat cgcatacttg
     9781 cttgtcaagt taactacttg atcaaatgta tattgcgtaa aatgattttc taagttcgtt
     9841 aataaaggca taattgaact actaaattta atagatactg catcagaaaa atcattgaat
     9901 tcagtaattt ctagcggtga gatgactttg tattcagtct taccgttagg tttagttctt
     9961 tgaattttaa tgacagattg ctgatgcaat ttttcaataa cttgttttaa tcttgaatgt
    10021 tttgaagaag atgaactaga agacatcaac gcaaataaag cctttttaga tactttgacg
    10081 gtattattaa aaggcggatt tttagggtca agatgtccta tagcgtaaag ataaattttt
    10141 tgtggcatag catccatttc aacaatgcta tctacaagtt gattcgataa agtaacagtt
    10201 aaatcaaact tttttagatt gctttcggta gtttcaaatt tcgggtttac attcttttct
    10261 gttattttca tacgattgcc tcttctttct aagcttggta cgagcttaaa aacttggaac
    10321 tggtacgatt ccattgaata agtatagacc tgttttcgat acgttacaat aagaaatgta
    10381 tcgtaaattt ataacataac tcaatgtcag taaaacacat tttatttttt ccaatcaaat
    10441 ttcattgaaa atacagcaga aatcgctatt ttagaacatt ttcaaaataa aaatcctttt
    10501 caataaaata cgaaattata aaaattacca aaattaaaaa acaaatattt ttctagtttt
    10561 tagaaataaa ttcacatact ttttcttttt ttggatatat tcggaatacc acatcgcttt
    10621 ttgtccacgt ttgcatcgct ttttgtccac attcacatcg ctttttgtcc atgttcgcat
    10681 cgctttatgt ccaccctaaa atctatttaa gattgatata aagccttttt ggaggttgct
    10741 aaagttttaa agattaaaat atatattata aatataaata aaaggggaag ctgaagcttc
    10801 ctccttttcc tttttttcaa ttattcaaag ttacacaagc aaaataaact cctagatagt
    10861 gttagttttt tttaagattt tttattttta agattttgaa ataagagagg agtaatcctc
    10921 ctttattaaa tatctgttaa tatatctgtt aaatatctgt taatatatct gttaggggag
    10981 gcttaatctc ttgggagagt aagtattaaa ggggtataaa ggtaacactt ttggacagta
    11041 aaggtaacaa aagtggacag taagggtaac agttttggac agcaaaggta acaaaagtgg
    11101 acatttgagg tatcacacta ggataagacg ttaccttcgg ttttcttgat ttggaaggcg
    11161 aaaaaataga aaattagatt agtaacaaat ctttgttgac tgttaccttt agttgtgatt
    11221 taatttaggt aacaagcaga aaaaattgct tcctttaatt agtaccagat taacatgatt
    11281 aaaggagcgc aaaaagaaga ttggagagta atcaatgtct caagaagtta ccgaaaagat
    11341 tattgatagt gatgtagatt tagtatcaga acaaacaaat gcaattgtgc gttataacaa
    11401 tggtctgaat acaacagctt tgcgaggatt taagcctgtt gaaatggatg tgttttgggc
    11461 tattttatca aaaatgaaac gtcaaggaac agcagaagta acttttgatt tcaacctctt
    11521 tcgttatttg gtcaaatacg acagaagaga aaaggacagt ttttattctg tgttaaaaga
    11581 tttgagtgac aaactaggta atttaaccta ccgttttgaa gattcagacg tctatgaaca
    11641 gctgtggctt tttcaaaaat tccggataga taaacagaag gaaacagtta caattaaggc
    11701 aaatgaggaa tttgaattta tcttaaactc aattggcaaa aactttactc gttttgaact
    11761 tgataatttt acaaaactaa gaagtagcta cacaaaagaa ttgtatcgtc atctcatgca
    11821 atacagaaat aaagagtggc gaaatggtta ttgggtagtc aaagttgaag attttagaag
    11881 agcattaagt ataccttcaa gttatagaat gacaaatatt gataaaagaa tactagagca
    11941 ggcgaaagaa gaatttttag ctcctgatga aaacggaata caggtatttg aaacttttga
    12001 ttatgaaaaa atctatgcaa agaaaggaag aagagttgat cggctcagat tcacttttag
    12061 tgagccagaa tcaaacttgc caaccatttc aatgcataat tggttagaag aagattgaga
    12121 agaagcaggt tgtaatttta atacaacctg cttctttaaa aaagtatggg taacactttt
    12181 ggacaataaa tgcaagaagt ttttttgtaa gcaagtttca gtctaaataa tatttgaaag
    12241 aatggctaat ctatacaaat tttaacaact atgggtaaca cttttggaca agtcaagaaa
    12301 aaaaacaatt tttcttaatt tgttgatcga ctaaaggtaa cacttttgga caacacagaa
    12361 taaaaagtcc ggtgatatca gttttggtag gaaacatctt aatatctttg tgagattgaa
    12421 ggtaacattt ttggacaagt caactatttg ttaaaagtta atatagagta attagataag
    12481 ttttttcttt tcgtctgata aatggataat attagttatt ttattgctaa ttagtctttc
    12541 atgatgactg aaatagctaa aataaatatc tcgttggata attgctgata ctttaaggga
    12601 tatctaaatt tgctgattga tttatttatg ttattatgat attataataa cataaatgtg
    12661 ttacgcccga acctcatttt aaaaaaatga aggggtgaga caatgaatgc tattaattgg
    12721 catgaatttg ttaactatat ggagagctta ctagatgatc taaaaagttt tagtattgct
    12781 gatgcagtaa agcatgggtt accagttagt acaacgatga aattacgagg attgaaaatt
    12841 ccagatgaaa ttattaagct gagaactaaa acaattattg aaaccgcaaa agtcgttgac
    12901 aatatgaacc atgaactaaa aggcaagaaa acaacttacg agaaagattt tgaacgtttt
    12961 ttaaaatctg ttattggaaa atatctaggt aaaaaatctt tcagtgaatt gagagatgaa
    13021 gagattgtac ctactccaat ggttagcaaa atccgaaaaa acaaagccga ggggaattac
    13081 tatcttggta caatagcaaa aatcattgat tatttggaaa ataaagagca aaagaaagga
    13141 acgaagaaag gaagataatt tttgtgttaa atattaatgg ggaagaatat accgaaatga
    13201 ttcaaaatcc cgaacctaga attaccgaaa aaacgtctga ttgtttgctc ttttatgaaa
    13261 gggggcagac aaactaatgg aaaaaaacgt caattcaaca tctaccaaag atcaatacag
    13321 tattattgga gggttgcttg gtgataagga taagagaaca cgtcacggat tacgcattat
    13381 gcttgcaact tttctaggag tgcttttttt attaacaggc ttgggtagct acatttatca
    13441 attaggaaac tataattatt atctcgtgaa caatacaaca cctataggct cttcattgga
    13501 gtttgctcga tcaggagcag agatcactat ttcagatgtg tggacagatc aaaacagaga
    13561 tgtaacagta gtaaaactcg gttactcgca aaacgctaga aagttgttat ctacgcaagg
    13621 aaaaaactac aacttatata tggcaacgaa agaaaaagat cgtcctaaaa agcttgaaat
    13681 gagctatggg atgttaagta ctgatgggga tgctttctta ttcctaaaag gtaaattaga
    13741 tgaaagagct tatcaagttt ttattgcaaa ccaagtatca ctaatttctg gtgatgatac
    13801 agctgacgat gataccaaag tcaatgtgaa tgaagcagat tcagttacaa aagcactttc
    13861 tcaatattct atgaatgatg ttaataatga aggagtaatt tcttttggga aaaaagcaaa
    13921 acctgttaat actcctgata atatcaattt cagaataaat ccatattcag attcaactaa
    13981 tgtctatcaa ggaagctttc ttaccaaaga tggcgatatt gattattcaa aagttgtagc
    14041 agttacaagt aagaataatg ttgtaagtaa gttagaagat cagttaaatg cttcaaatac
    14101 taacatcaag aaaattgaag ctacaaaagc tgagtatctg gaacgtttac aacaaaatcc
    14161 tgacgataaa gattcgcaag aaagtattcg tcaactagac agtcgaatgg agaccgaaat
    14221 taaagcaatc aatgatacac aaaaattgat tgatcaatac aaaaatgctg actttaacaa
    14281 agattctttt ggagacatga agacgacatt taagtaccta actctgactg actagaagta
    14341 aattattctt attttagagg aagtgaacac aaacagatgg aaaatagtac cgagtttttt
    14401 aagaatattc aaactgaatt taatcatgct ctcacaccaa tgaaaccacc gaaacataag
    14461 ttagtgggac gtgatgacga actccatgag ttgtcactga tcttgaatag accggaaaca
    14521 ccgcaagcta tcttgttagg tgaagccgga acaggtaaaa cagcacttgc aagtgaatgg
    14581 gctgaaagac agcgacaaga tggaaagaaa gtacaagtat acaaattatc aatcggacaa
    14641 ttgcgtgttg ggggagatga tgtcctccaa acacgtttag aaacattaat tccaagattg
    14701 aaagaatatg agcgaatttt aaaatctgag gacaaagaaa atgaatttgt cctcttcatt
    14761 gacgagtttc ataaagttgt tagctctttt ggtagtggca ataaaattgg gggtgattcg
    14821 ctaaaagaac cgttagcaaa tgaatcactt caattgatta ccgctactac aagaaaagaa
    14881 tatgaaaact atatcaaaag agatgatgcc ttagggagac ggttacaacc gttagaattg
    14941 aatgaactaa aaagcgatgt tgtcgtcgat attttgagac aatggctaaa tacatcctct
    15001 gttaaagatg atcctcaggc ttcttttaaa ttatcgcaaa ggattcctga tgaattactt
    15061 caagaaatcg tacaagcaaa caagctttat cgtgaggatt tgtccgaacc ggctaaatca
    15121 attgccgtaa tggaggattt gattgcaaaa gatcgagtag acggaaatgc ttataatcga
    15181 gaaagtctat tgcaaatatt tggtaagtat aatattcagc tagattctga ttttgatatg
    15241 gaaaaacttc aagaggaatt aaagtccata aaagggcaac cgttagcagt ttatactata
    15301 acaatgttgt ttaaacgtat gaagcttgga tttgatcgtt ttaaaggtcg aaagcaacca
    15361 aaagcaactg ctctgtttac aggatcaaca ggggtcggta aaactgcaat ggctaaagcc
    15421 gtggcaagag gactttatgg cgatgaaaat aaagttctct tagttaatat gccggactac
    15481 aaaacaaaag atgatgcaat gcgttttaga cgactcatag gtactcatgt aaggcatgat
    15541 ccttctgcga ttattgtgtg tgatgaatat gagaaagctg gtgtagaaac actcgatgcc
    15601 tttttatcaa ttttagatga aggtaggata agttttactg aaagaggatg ggatgatcga
    15661 gaagttcacg acactgtttc attgtcaaat acaattttat ttgcgacaac aaatgcaggt
    15721 gcggagatgt tcgattcgtt aaacagatat agctcactat ctcgtgttac aaacaaggaa
    15781 aattctaatg aatatagcac tgaactaaaa agagaatacc gaaaagtcgc atcagggatc
    15841 aaacaagcct tgattggtga aggtctaaag cctgaagtta ttaaccgatt tggacgaata
    15901 gttccatttt gggctttatc cgaacaaact cttctggaaa ttgcttataa tgaaatgttg
    15961 aagagtgctg aattagtacg aaaacattta aatatagatt tacgtcttcc acctaggaaa
    16021 gaaagagtat atggtcaaaa tttttatgca gacgatctct ccatgcactt agtttttgac
    16081 atggcttcac aagaggattc taaatcaggg ggtgcaagga atatcttgca tttagttgaa
    16141 tctgagtttg aagaagcgat tactgaagca ataattactt atccaaacgc aaaaatattc
    16201 gatgttaagt tgagtgaagc cggagcgttt gaaggaaaag gtgattctaa tgctgaaatt
    16261 attgcaaagc cttccgttgc tgaaagtaaa gaaaacaaga ttgtattttc gattggaggg
    16321 gcgtagctat gaaattcaag aaatatttac tacaaaacct tagaataaaa cgatgggtcg
    16381 taagaggtct agttattgga ggagtattag cagttacttt aggcgctcct tttggaatga
    16441 atgatccaac tcctgacaat caagatagca aacaagaaac agttataaat aagaacgttg
    16501 catatgcgga aagtaaaccg gcagaacaag gaatgtggac actatatgct cgtatcctaa
    16561 tgggagataa agaagttaat gatagtgccg ctaaaactgg acaaatgaat ttgttaggac
    16621 aaggtggtat cagtgccgat ttcccttatt ctgacatttc taaacaaggt aattcgattg
    16681 cagggggtaa tgcaggtact caactagcat ctactttagc aacttatagt tactacggat
    16741 atattgaaac agtctcagga aatgctattg ccagtcaagc atcatccatt ctaggaagta
    16801 ttggtaggac gattggtagt tttatcggat caattagttt aatcctttct aatattgctg
    16861 aatccataaa tgaactcctt ggaaaatttt tcatgagtat gaatatattt tctcttatgg
    16921 ggtggggaga aggtggatcg gatgtatcta atccggtatc taaagcatta actagcttgc
    16981 ttaacaattt gggattaaat aatgaattat ttaaagcgat agcaagctta tctatgctct
    17041 ttttcacagc aatactaggt tatcaaggaa tgaaattatt gtcgaaagat ggtgttaact
    17101 cgaagggatt atcaccagta cttgaaaaat ggattgttcg tatttttgta ttgtttatat
    17161 tcttaccagt ggcaggatcg ctattgggag tttatatcaa cggcatccag tcagcaaaaa
    17221 aagatggaga tataccaaca aatgttgttt ctgactacat cattaacaca agactttggg
    17281 cttctactca aaatcttgct ccatcatctg atactggtgg tgatgtacct gacggaaagc
    17341 ctacatccga aatcaagttc gttgatacag attatgaacc atctaaaaaa tctgcaatga
    17401 taagagcgat caatactagc agttatgcca gacaaaataa tgatctagat tctaattcag
    17461 tcggtatggc tctattaaaa gaatggtcat cgaatgatac tttcaatatt aatacttatg
    17521 ccggtgatgt taatgtcgcc gaaaatgatg cttatatggg aagagcgcct gctgtttgga
    17581 caggctataa tttaggggat ggaaaagaag gaagtgcaat taagaaacca accaatttaa
    17641 atggatatat ttggtcagca aatcaaaatg tgacagacga caatcgcaag cctgatggaa
    17701 aaggaacagc gcataacttt gatgctactc aaccttgggg cgttgctaac aatgcaactt
    17761 ttagcacaca gtcggtagct ttattgctcc aatcggcact tgatacatcg ggagctaagt
    17821 tttatgcgta taatatcgct ccttcaggaa ttcaaggcag tgctaagaat atgtcaacag
    17881 taaaaacaga atggcgtaca gcatccttag ttggtcatgg agctatgggt aagtttggct
    17941 cgtggctagc gatgaacgct gaatcaatcg ttttagcagt tctttactta gcatgtgctt
    18001 gggcgatgtt caatgtgaat atcgtgaaag catttaaacg tgaatttatt cggatttggg
    18061 aagtagttct aacaggatca cttgcatcag gagcaggtgt gatggcaatt tcattaggtg
    18121 ttgttacaac atctctgatc ggactacaat tacctatctt tctgattact tttattcgtg
    18181 catttggtga tactgctgtg ggattcattc ctaatacatt agttggcgat ggcgtagcaa
    18241 atattgttcg atctgctatg attttaggtg taggatatct tttagtcttt aaaaaaggcg
    18301 aaaaagtaaa taatttgatt aatatgctta ttggcttacc acttgaagta gcgtttgggt
    18361 ttgatgaacg tgctaagtta ttatttggta atagaaatga tgctgtgcga gttgtggacg
    18421 gcgtttctaa agcaatcaag aaaagccaag gagctaaaaa tccctattat gatggtggca
    18481 acagctcagt aaaagatatg gttgcaggag gtcttggagc agttggagcg caaaaaatgg
    18541 ctgaacgttt gaacaatatg ggagatagca atgctgatgc taagtccatt gctgataaag
    18601 taattcctga aacaccagaa ggaatgtcat tcaacggtgg cggagttggt tccacaatca
    18661 ataatacctc tttcaaagat ttagttcgtc aagatcaact acgtaataac tcccaacaat
    18721 atattgatca tttaggacgt atggttgatg aaaacggaaa ctttgtcgat gaaaatggtg
    18781 aaatattaaa agatagtaaa tacggtaaag atgctaaagg caactttatt gacgaaaaag
    18841 ggcgtttggt cgatgaagat ggaaacctta tagatactaa tggtaaacca ttggaagata
    18901 gtgaagatgg taatattggt atggatagcg aaggacgttt aattgatgaa aaaggtcgct
    18961 tagtcgatga agatggaaat cttgttgacg aaaatggacg caggttgcta aatggtgatt
    19021 ttggtcatga tagtaacgga cgtttagttg acgaaaaagg tcgtttagtt gatgaagatg
    19081 gaaatcttgt tgatgagttt ggtaataaac ttggtaaaca cagcgatgga tataatgtga
    19141 atggagattt agtcgatgag gatgggaata tcattgagac gagagatgcg cttgtggcag
    19201 atcgaaatag agaactcgaa caacaacggc atacgccaat tgctgttgca attcctgaga
    19261 atgaagaaga cgagattact ttagatcaaa ctcatcaaga actgaggaat gaaatgagtg
    19321 gtgaggacgt gtcagacaga gtgcatcggg aattaggaga tggagcatct ggtgaaagtc
    19381 agtcaagaga gcttaacagc aactttgata atagtgctat tcggaatgac acagtactta
    19441 aagacagaga atcgctaaca aaagaaacgg ataaagaaca atcagatgtg aagaaaaagt
    19501 tcattcctac tcctaatgtt aatcaaacag ataaatatga aacaaatatt ggatcaggaa
    19561 tgtcgaaaga caatcaatca attagagaac ctgaactgac aaataaaaat aatagaacaa
    19621 ataattctaa atctacttca gataattcag ggaaatctaa tcaatcaacc aagaaaacat
    19681 caacagctaa atcagccgtt gaatatctat caaaaactgg taaaaatgtt tacacctcag
    19741 cagataaagc tttagcaaaa gctccaaaag gtagtctagc agggataacc tatgaagcta
    19801 aaaacgaagc tattaaaata ggtaaaggaa cggctaaggt tgccaaggct actgctacag
    19861 gagcatccaa aactggtaaa gtagtgaaga aatctaccat gtcagtcaag gactatattg
    19921 taaaatacgg taatcaaaaa tcaactgaaa ataagtctga agacgagtaa aaagaaggag
    19981 cattgatttg ctccttcttt ttactttgat ttctaactga agatgtcaag gaaaatttct
    20041 atttatgcaa aaaaattatt ttaaattgtc tataaatgaa ttaaatattt actgttcaaa
    20101 gttgtataat taaaaagggc ttatgctggt aaagaacaga attattatct aaacaaaaac
    20161 ttgataaacc agcattttta gccaataaaa aaagtgaaat aatttaatgg aaaatctctt
    20221 ttaatcatcg aaaatttatg ttattatgat aacataaaga tgtaaatatc gagacgtctt
    20281 tttcttagtt agatcattga caagtgaaca aataagattt gtcgatgata taattaactt
    20341 attaaaaata ttaaaaagga ggtttttata tgttcgattc tattaaaaat ttggttagcg
    20401 gaatgacgcc tgatatgaaa actttagtac aagttgtttt gtatttcttg gcattcgttt
    20461 tttcgttgaa accaggattc actgcaatga aattttttgg tgatgcaaaa tggggagatg
    20521 gattaaaata tgttggggcg attattgcaa tctttattat tcctgtaatt acaaccgtta
    20581 tgctttacac aatgggtact aaaacaggta atgatttgaa ccaaaaagct aatatcatat
    20641 cagcacttat tccagttgtt ggtatctatc tagtttcaaa atttccaaaa aatgaactgt
    20701 taggttaaaa gtgaattgaa caaatttgga taatatgccg atttgttcaa tttacttttt
    20761 accaaaaaac tacgctccaa gcgtagttta gaagtgaggg aagaaagtaa atgtaagatg
    20821 gtttttgata gagaaaaaat gttagctcac gccaacgaag tattaatgag cagtctgaaa
    20881 ggtaccgaac tggcaaagat aatgaatatg aatgttaacc agttctatga ttatcgaaat
    20941 gggagtaaaa agattgaaaa agccagactt gaaacgctta ttaaattcga aaaagcatat
    21001 gtatatatgc tagataaaca gaaaagaact attgactgaa aaaaggagtt ttacaataat
    21061 ggcaaaattc aaagatatta ccgaatctat taattatgtg gcagaaacag ttcctgtagt
    21121 tgcactctct ttgaagccac aattactcga agtgtacaaa aaagaagaaa aagaagcgaa
    21181 ggcaaaaaaa gctaaagcaa aggtatggaa agaattcgat gcgttgctga ccaaagattt
    21241 accaaagaaa aattatatgg taattgaaga tgtacaaaag ctcaacagtg agggagttat
    21301 agatgaggat gatgctattc tcgattctga gaagtatgtc gttctattga agtcaagttt
    21361 gaattatgta gctgatctac cagaaaaatt taaagagaag ctattagcag gtgtccgttt
    21421 tatggatagt agtggtcaat tattagttat tccggatgat cctaatgtgt ttgaatcaga
    21481 agttgaagaa gctacagact tctatagcgc agtagagcaa ttagaagtag ctactaatgg
    21541 attagaacga attgctgaga ccttcaactc ttctgaagaa gttgaatttg aagccgtagc
    21601 agaaaatgta ccagatgaaa aagaagctct ttttgtggat gataacaaac caaccgaagc
    21661 agaaaaccaa gaagtaagca tagaagaaac acaaatacaa acagaaacct accaacaacc
    21721 aaaaattgat gaaaaacccg aatcccaaag tgacaaagaa aattatgttt atgaagctga
    21781 aaaaatcaca tctgaaagtg atgtaccgaa aaacttagat gctgattttt tagaaaaaaa
    21841 ttttgaacag atcattgctg acaaatttca acctgtagtt ttagatgaga ttaatgaccc
    21901 tgtcgattta aacgaggaga tgctatccat acctgagttg aaaccattgc tgtttttagc
    21961 taaagagagt atgaacgctc gcatctctat tgctaataat aaaatcaaca gtgaattaaa
    22021 taagacgaag gagcaattga tcctcaaagg aaagcaaatg ttagctgatg agcttttgcg
    22081 gatagaggaa gcaacctcat taaatggtca aaatcagttt acaaatacac tatcggttgc
    22141 taaagagagc tacgaagcag aagcatctaa aattgatgat ttagtgatgg aaaaatccaa
    22201 tatcattcgt aaagattatg atatggcgaa acaggcttat ttggatgctg aactaaagaa
    22261 actagagcaa cggtatgatg ctgagcattt accagaagtt aaacaacaag aagatgaata
    22321 tagaaaagca actgaagaaa gtcttgatca acagtaccaa gaagcaattg aatctattaa
    22381 aaacgatgca ttgaaacaaa gccaagaagc aaaagaagtt gtggtggaac gaattatcaa
    22441 ttcattgaaa ccagaaattg aaaaatcatt aacagacgtg caagaaaaaa ctttagagat
    22501 tgtcgaaaaa acaaagtcag aaaatgaagc tgagttccat gatacaaaag agaaaacaac
    22561 agatgtggtt gtcaaatatt ttgcgaacaa agaagaagtt gaaaagcagg tagctaacaa
    22621 cacgaaagaa ttagaaacaa aacttgtaga gcaacaaaaa actatcgaag aatataaaga
    22681 tcgaatgaaa gaggtcaaag atttagcaga gggttataaa ttaaatagcg aaaagttggc
    22741 agaacaaagt gaagctttaa gagaagactt atctcgttcc cgaagtgatc tagctcaaat
    22801 ggcagaaaaa acgaaatcat tagcagttgc tacagaaaat caatcaagtt caaaacgtga
    22861 ttttacaagt aaaaagatgg ctactatcat ttctgtcgct gcaatggctt gcggaacgat
    22921 cttgggatcg tcctacttta ttagtcataa taatcaacaa gcacaggctc aaactcaaac
    22981 atctatttcg agagtggaaa attcgattgg gacaaatacg aactctgctt caacaaatag
    23041 tagctatgaa gcaacaccaa ctacagagtt caaagttggg aaagatgttg tcatcagtat
    23101 tgatgggaaa acaactaagg ctgaagtgat ttctattgat ggagaaaaag cagttgtgaa
    23161 aactccagac ggaaatcagt acaaaattca agctcactta tctgataata actaaggagg
    23221 gctattatgc gagaagaaaa aatagtttat ccagtaattc aaaacaatca agaaaacatg
    23281 acctcttctc agcacttaca ggaagcacag ctcgtgtatc aggtaaatga actaccacaa
    23341 acgaacgaga caatgagcaa gtcaatatct ttaattggct tgcttattgt tgcaatagtg
    23401 ataactgtag gtgtttaccg taagttgaac gtgaaaggaa gtatttctga tggcagataa
    23461 ctcaaactat ggatttaaac ataacttaca tcaaaaacct tctgaaacaa ttgtcagagt
    23521 tgaatggctt gaaaagcatg tcaatagcac ctattctgtt acagcaaaaa gattaattgt
    23581 atcagctata gttgttgcag tcgttgttct tggatcaatt gtttacttag tttctgatac
    23641 gattaaactg aaatttattt ttgttccaac gttattaatg ataattggat ttcttattct
    23701 aattagccag tatatgttta ttgatccatc tagtggttca ttgatttctg gttctattag
    23761 actgttcaaa tcagtagtta attcagcaag agtatctatg gggaaaaaga aaccatttcg
    23821 aggcacagag attttaaaag tgaaacaaga tggaacaatc gtatatcgag atgggagtgt
    23881 agcattaatg ttcaatctag atggggctac atcactaacc gcttttccag aagaagttat
    23941 ggctcaggaa tcgaaatcaa tacaatatca aaataccaga gatcgttcct tagctgaaat
    24001 caaaatcact tcatctcaac ctcagaatac ggaaagacaa actcgaaata tgaaaataca
    24061 aaaacgaaat gcaaggagta acaaagcagt ctttgacata atagatcagc aagaacgatt
    24121 tgtatcagaa tatattgatg gtgtgaaaac aacagtaatc caatatctta tcttgaaatc
    24181 tcaatctaag atggtattgg atgaaggtgt ggaacgttta gaaaactata cgagtagagg
    24241 actttattat agtgtcactc agttgtcagc taaacaaaca aaagaaatat tatctgatat
    24301 ttatgcactg aaatagaggt gagagattaa atggaaatta tgggtagatc acaactatta
    24361 aatttcaaaa aaaagagaaa aactaaaaaa gaacaaaaaa ctagaaattc aaaggtagtg
    24421 aataatacct ttgttagtga tttaacatct ttagttggtt atcaatttac accatcttac
    24481 attaggacag gtaagcggtg gggaacaatt gtgaaattag tgaatactta tggaatgaat
    24541 agaaattatg gatttggttg gatggttaaa gctattcctg aagtgagagt agaaggggta
    24601 aaagcctatc taattgaagc agataagcca gtgtcacaaa aagatcaaca agaaataatg
    24661 cacgagaatg ttgggggatc aacgaatagt tatgaaaata atttagaagg aaaaaattca
    24721 gatgctgaaa ttagcaaaac tgttatgcgg attatggatt tgaatacagc atctttacta
    24781 gacagcatgg caaataaaat tattgattgg aagctagaaa tcctattagt atccgattct
    24841 cctaataaaa tcagcgaaca gctaattaaa ctccaacggt tgtatgatga aaaaatgtat
    24901 ggattaaagc ttatgtcata tggaggagat caacgtgatc tgtttgatag acttttaagt
    24961 gaaccaatcg ggaatgtcta tgagtatacg tctatgagtt cggattttgc aggaaatgat
    25021 catgcaattc gcaaaggttt agatgatgcg aatggatggg ctatcggcac tatgtctact
    25081 agctacgcaa gtggtgtagc ttttatggca ctggatgatt cttttacaag taaagtttta
    25141 gtggcatcac acaaaaacgc tacaattaaa ggctatgatg aaaaaatctc agcatcatca
    25201 ctttgggggc aattgattgc taataatgca atggcaaatc ataaacgaac ttttcatatt
    25261 gtcttaaata aatttgatta ctttggtgat ccaactggta gaacatttgt tgccaaacct
    25321 tcgttaaaca gtgtaataga aaaggttaat ttggctgaag aaggtcttaa ctctttggag
    25381 ctttttggta atcaaaagga cattggtgat ttatatagac ggaatctcga taaactaact
    25441 cagatttttt atttgttagc aggcagaaca ttagattctg caactagagt tttattgaaa
    25501 aaagaattag gtaactttta tataagtcag aaactttggg atattaatta tgaagaacgt
    25561 tcaaaacttt tggtgaacag tagtgataca atgccagttc ttggggattt tattagctat
    25621 ttgactaatg ctgaaacaaa agccaaaaaa tctggtactg aaaaagaagt cgatcgtatt
    25681 attgtattaa aagacacatt gagaacagca ttagacagct tctctaggat gtttaatcaa
    25741 agaacgacac tgaaagaaat cggtaaaagt gacaaattac agttttacta taacttaggt
    25801 gatctaagag cagaaaccaa tgttatggaa gctcaatttt taaatacctt tgatttcatc
    25861 acatcacaag caaaaaaaga tgatattgtt atgattcacg gcttcgataa gttatctatt
    25921 gaaaccgttg ggctaattaa aaaaagatta acaatgcttg aagaagatgg aattcgtctt
    25981 gcctttctat ttgatacaat cggttcagga gaagacaatg aatacaaaga agatattgaa
    26041 acagctgata tattcaatac agatggaaaa atttaccaaa gttttgaaag tgattttaat
    26101 tacactatca ttggaaagat gaccagtgga gagttaatga agtatgaaaa aaaagttgct
    26161 cctgctagaa aaggagaaga tgatcaaaaa ctttctgttg atttgagaca gtatttgaca
    26221 acaggaagaa gtaataaatt tcagatcagg agaccagtgg atctgactaa taattttgtt
    26281 attggagagt ttattcttta agttttatct ttgattttga gtgtataagg aaaggataag
    26341 aaaaaacatg tatatttgag actaaaaaca gtcttagaga acatggtacg ttttgtgaaa
    26401 agagaactat agaaatttca taaagtgaaa ccttattgag tgaaataatt atagtggagg
    26461 ttaaataatg aaaccaaaca taaaaatttt agatcgaata tttctaggta gagacacaga
    26521 agtaatccta attcaacatg aagaaggatt tgaagttagt ataggtattc agaaacttca
    26581 aaaacctcat tattgtaatc agttgtataa aaactttact gatgaagaaa aagcgagagt
    26641 tttttttaat gaagtcaaag gtatgagaga acagtatgag gtggttgaag catgaataag
    26701 ttaccagaaa agaaccgtgt atttagattg aaaggtgatc tcagtcaatt taaaatagat
    26761 gagaatggac aattttttgt ttggatgcga catgagcatt gttggtgtaa tccttttgtg
    26821 ttaaaaaaag aaaatgaaat cagaactaaa attgcaaatg gtgagtggga ttacctcttc
    26881 agatgggaag atgaatcttt tatagcaaat gatatggatc atgcatttgt ctcatttctg
    26941 gataatacat ggggtacttg gtacgattgt tacctagaaa aattgggctt tcaaaatatt
    27001 gatattgatg ctattgaatg tcttaaagaa gtcgatcaaa agtatgaaga agaaccctat
    27061 tatctcttgc aacaaaaatt agccaataat tcagtgtttc aggtagaaat ttgggaaaat
    27121 gaagatggaa cttatgaggg gctagcgcaa gaaataccct tctcagatag gaagagttcg
    27181 atttgaaaag agtatatcag caatttttat gaagtgaaag caagcttaca atatagtaat
    27241 ggaaaattgt ggttagctgg aaggtatatt ccagctaacc aaatcttacg ttttctggga
    27301 gagtggcgtt ttaaaacaat ttcctaggaa aaatagttaa cataaaagga atgaattgtt
    27361 atgaaacaat atttaaatga atggaaagcg atagaggggt cattagtaac gcaaagaata
    27421 aaggaattac ctgattgctt agagaaggat catttgtttc aaatacgaga aatgttgaaa
    27481 aaagaacagt ttgatccaga ccaattttta gtagtcgagt atccaactat tggagtgtac
    27541 tgttgtaacc atatcaatga tggaaaatat tttattattc aggagtatgg aggacagtta
    27601 actcctttct atactacatg ggaaatgagt gaagaaggaa tcaataattt tccatgtgaa
    27661 agcatcgaag attcaatttc acacaccgaa tgttaattga ttataactat aaaaaaggat
    27721 tgaacattat gttcaatcct tttttcaatg aaatgttttc cgccatttca ttgtttggtg
    27781 cgatttctat tttattatat caaaataaag agagattcta aagaaagaag agggaaatat
    27841 ataaatcaag cgacagtata tttattatta aatgctattg tgagaatata actaattagt
    27901 ttaatttgaa agtaaatata cgctataaaa gtgcatcttg tgttataaaa aattatttta
    27961 ttttgtgaac ataatttaac aattctttct cggaattgat ttcttttctt aaatagtctt
    28021 cagacttatt aataatatta tctattatgt ctagatacat atcacttttc gattcagcta
    28081 attcatacag tttttttaat tctttatcct ttaattgaaa accctgatcc atagtcactg
    28141 catttggata tagaagccca ctataatgtt tacgtaaatt cacttggaat ttctgattat
    28201 aaaagtctaa cagattagaa ataaaaggcg gaaaattact gtttttgtaa aattgattat
    28261 ttccatttag gttgtatagt aatttgttaa attgctcctg atttaattta ttgtaaatcc
    28321 atggtaatac ttccatatcc ttatctgcta acctgaatga actagcatcg gtaagatgtt
    28381 cgatcataaa atctatgaac atctcttttt caccaaaata taaatattga ttatatattg
    28441 tttctaatgt tgaagatggt agcgaagaaa ctctcatttt ttgctggagt ataggatcaa
    28501 ctagactatt taagtgattt tgtaattctt cattgttgtt tcctagaact gcaagggaac
    28561 gtaaacggta gtaatattct atttctgtta gtacttgttg tttcggttta aaatcattta
    28621 ttgatatttg taaattttga attgtctcgt ctgaaaaatc atgttgtaat tctggatggg
    28681 tagctataaa agtaagtaaa aagaaccctt ttgtatacgt gatctgttga ttttcaccaa
    28741 gtgatttatt aatttcctct cttgattcag ctgtgaacct atactttgca atttcttttt
    28801 ttagaatatt taaatagaat tctttattat caaaaattag ggcattaagt agtctgaaag
    28861 tactttccct atttctatct gcttcctcat ttccataaga taattgaaaa acaaacttaa
    28921 aggctgtctt acataggttt tctttggctt tttcgcttag tttatttaga tagctatttt
    28981 ttagtgcaga gtgaaattct tcaggtgtaa cagacatagc atgtatgcga cttgcatatt
    29041 gtataatttc gatcgttact ttttttccta atattggatt ttttaggaat ataatttcat
    29101 aggacttccg tataacatcc tgacaagttt cttttgttat atctcttaat tcccaagtat
    29161 taccgttgta agtgactaca ggatgagctg aataatttct ttgatcctta atatatttta
    29221 aatcctcata ttcatagcta tcaattagct cagttgaact ataagctttt tctagtagtt
    29281 ccatttccca ttttggagag tttggatcac tttttcttag tctagctata tcttctaaaa
    29341 ttttcttaga agtattatcc tcgtaaatat ttgctaaatc agataattta tcaattaaat
    29401 ctaaaataag cgcactgtaa ttgacagcta ttgcagaacg ataatttccc tgataaaaac
    29461 tacttctaac ttcttctaat aatggaataa ttctaggatt tttaactttt tttatttcat
    29521 catctaatat aaacatataa atctcctttt tttatttgta tgacaagttt accataaaaa
    29581 aaaattaaaa agcgagacat atttatgttg ttgtgttatc ataataacat aaatatgtag
    29641 agtgagatga tgaaaaaatg gatttgaaac aatcgtttta catctggtta tatcctgata
    29701 atcctatgtc aataatggct gatatttttg tagttagcat cttattgtat ttattttatc
    29761 taattttctt tcacaattta atcgggtaca tgattcttga ttggaaagga atgttcgata
    29821 tagaaagaaa accatttgct aacaatcaaa cctataccgt cttcgaaagt ggagattggg
    29881 aagaaaatga agttgatgtg atccatgaaa ttggattagc tttatcagga atacaagatg
    29941 ctgatgtttt ggtatcaatg acaacggata ctggatacaa cgcttatgag gtattttatc
    30001 ttatgtattt tatatggcgt gatggtcaag aaattatcaa tggtcgtgct gaaaaaacaa
    30061 tcaattctaa tactgaaatt tctttttgta tgggtgaagg ggaaatgatt gtatataaag
    30121 atgggtcagc aaacattaaa acagcctttg gtgatattga aacaagtatt aaggaactta
    30181 gggaatatgt gcagaaccca tataattttc aatatttagc aggaagaata aatttagttt
    30241 aggagtaaaa atatgaaaaa aattataaat caaccaacaa atcacttgat aattgaaggt
    30301 gttattttcg taacaatgta ttttactgta ggaaatggca tctcaaatac aatcattcaa
    30361 aaaaatccac aatacctatt atttagtctt tatgcttgga ttgtacaaat ggtttgggtt
    30421 tccatattga tgctgttgtt ttattggata gtacgggtta ttcttttatt gttaaacaaa
    30481 agaaaaaagg ataggtgaat aaaatgaaat caactaaatt gaaggttgta ttgttatcga
    30541 cagcagcatt aataactctt acagcatgtg gtacaactaa tagtgctgat aataacaaag
    30601 acacaaagtc tagtagtacg gtggttacta aaaacagctc tacatcggca tcaacaacaa
    30661 tttcttcaat gactgaaaat aatgctgaaa agtatcaaaa atacgaagac attaataaag
    30721 gtcaaaagcc ggaagaagtt tataccgact ttattaatac agtaaaaaat gatgaagatt
    30781 atgggaatga tccattgcaa aataaaaatc tgactatcgt tctttacaaa cctgattgtc
    30841 cagattgtca aaaagcagaa tcaaaaatca tgcaagaaat aaaagaagga tttagttatg
    30901 ctccaacatt aatgcatgat attaccataa ataaaccagc ttacgagtat cacgcagttg
    30961 ctgtagatat tactgatggt gtacctgagt ggatacaaaa cattcctggt ctggctgatg
    31021 agaacaatca atatcatacg ccaacagttg cagtagtaac accaaagaaa gttaatggca
    31081 cactatactg ggatgtaatg ggaatgacaa caaatacaac tgatgaaatg attgaaagta
    31141 caactaaata ttatatggat ttgggagcat ataaattata tcaacagtca gaacctgtta
    31201 tggacgatca atccaaagtt aaatagttct ttagggcgta agccctattt ttttaaaatt
    31261 aagtgataac aaataaatga tttctgaaac aaacgttctt actcaactac tcgaaacaca
    31321 caagctaatt aactagatta taaaggagaa tgcgtaatga aagaaatcag tgcaaatgaa
    31381 gctcatattc cgcaaaagaa tcaggttggt atatataagg tgcttcatgg tgaaggaatt
    31441 tataaaatac agttacttac cggttacaat aacggtgcaa atgggaagtg gttaaaggca
    31501 aaaagtattc gtgaacttaa aactgaagta gaaaaaataa gacttgggtt aacaagggaa
    31561 gaaataagta gactgagtga aaattcttct tttgtaatcc aaaaagaaaa ggagaaacat
    31621 ctacttcatc gggaactaat aattgaaaaa tactacgatg ttgatttacc tgatcagtta
    31681 agaattattg acgaattttc agagaaaaag tggaaatctg aaatataccc aagcttaatt
    31741 caatacaagg catcaggaaa gcccatgtat aactacacag gctttttaaa ctacacacaa
    31801 tataaatatg cctttcgcaa attaaaaggc attaaacaag ctgacattgc cctgtatgag
    31861 atgaaaaaaa tggatagatt gaaattgatt caagagttag tgcaaaatac atggaatcaa
    31921 gcgattgtcg aactagaaaa agaaaatggg aaaattttaa ctaatgaata tctgatcgta
    31981 aatgaaattg aagaattaat tggtttattt tcatgtgaaa atggtgaagt cttcttgaag
    32041 tcatcaccaa tctattcaat tttggacagt ccgtatcagt ttatacaggt aaggagatga
    32101 gttacatgtc tagcttgaaa gatgactata tccaagcaaa acaagagtat gaaaaaatac
    32161 agatgttaaa atctgagaaa gtcgaattat ttttaacaca aaaattagca gaggatcata
    32221 ttgctaactt agatgctaaa actttagagg aatatgatca gcagtttaat cagacacatc
    32281 acaatatcat tttgcttgtt gatcaggcaa agagaagact tgaaaaagcg gaatatgaac
    32341 tattagatca aggaattata tgcttggata aagggattcg aagatattat agtgcagagt
    32401 taaaaaagca aaatgtagac agacatgcgt taaaacatga aatcttagaa ttgataatgc
    32461 aacgaatttg aagggataga aagtaaatgt cacaaaacat tagtgctgta aaacaattaa
    32521 tagaaaaaga tttagagacg acagttcaga ggttagccga acgaatccat tttgcaaatt
    32581 atcaaaccat ctctaattgg tcaagcagga acagaaatcc ggaagaaatt ccaatgaaat
    32641 ttttttatcg aatcggaaaa gaatatggtg ttgatccgat aaaaattttc gaaaagacca
    32701 tgatttatta ctatcatgga acacctaacg aagtgttgga acatcttttg gaagaagcag
    32761 aagaaaaatc atcaatatta gagatatcac aaaatgacaa agctattcaa gtgaaatgtg
    32821 ttgatccaac aggaaagatt attgttggat ttgatattga aagaaaatct aaaatagatt
    32881 ttattactca attaacaaag ataaataatt taaatatttt aacacttaga ccagatcatg
    32941 aacagttgtt tatgagtttt aaaaaacaat tgaaagaaat acaaaaaaga tataacaagg
    33001 tgttttctaa tgcgtgaaaa gctaaaagaa atcagagtgt tttggataat taacaaagaa
    33061 tttattatct tgtatacact tggatttatc agcatgatct tgttttggtg gttatattta
    33121 aaaaagtaat ttaaaagtgt caaggagatt tttatccaga gaaggatgtg gaatttgcat
    33181 gtggaataat aaattaaaaa caggcttgtt attaatagtt atttcctgcg ctatgatggt
    33241 tggcatgata atacaaaggg aacaatctta ttttgaagtt tctgctaaca atgtaataga
    33301 aagatgccat tatggtcaac atttttggac tggggaagtc agagaaaata tagatcgtga
    33361 gtatgttcaa agaatcgttt gggatgcata ttctatcaaa gattatccta aaagtttaac
    33421 gagtagatta ttttacagcg aaaaagataa tcaaaaactc tcgaatttga tgatgaaaaa
    33481 agtaaggaaa cttgcacaaa actatttgga agaaaaagaa ggtaatagtc caattgacaa
    33541 aaattgatga cactgcaaaa aaatatagag ttcgaattag cttttttcgg agcattgttt
    33601 tttaggtgaa ctatatttca tcactaaaat cagagataac taacttgaaa catggtcaga
    33661 tgtgttactt gaagtctctg aataatcaat gttatctagt agaattaagc aactaaaaaa
    33721 gaaagaagta agaaaatatg gcatacgaaa atttacaatt agtagtcgca gaagttagtg
    33781 gggatatata ccttacaaaa gtaaaagatg gaattatgga cacgaattat aggagagttg
    33841 ctacagatga tgtgctaagc tcatcgacag aatggtttcg aaaaaatgaa gaatctgctg
    33901 ttcactttga aggaattgat ggaaacattc atagtttgtt ctatacaaaa gacaaagaaa
    33961 aagcaaaaaa aattcttgat attttgaaag gaaggtagtt aattaaccaa tgatataaga
    34021 gaatgtgaga ccaagtaaat acttggtctc tataatttta gccactagtc aattaaatag
    34081 ctaaacaatt ttaataataa taaaatatga ctgcttcata attaagaagt gcagaatttt
    34141 tctaagaacg atatttcctt gttgaaatga gtattgctaa caatttgatc acgaacagca
    34201 tcgttacaaa tgttgtatca atatttgata gattacatat tctattaaaa aagaaaagaa
    34261 aattattgat attatacaca ttagtgtgta taataaaaga gagggagtga ttagaacttt
    34321 gagcaattca ctaattgttt aataatagaa cgattcctaa gaagttcatt gttcattggc
    34381 aaattgcttt atcagattga aagttggcga ataaggtttg tagaataaca ccttttcaag
    34441 caaagcgatt tttgaaagct atgaaatttg tttaataaaa aaattcacca gataatctga
    34501 tagagactaa cccaattact aacagttgta attggtgtta gcttacaaat taattattgt
    34561 gtttagtcaa ttacaaattg tgaaacggca ctaataattg gaaaggaaaa atgaaatgtc
    34621 taaagattta cgagagctta aattgcgaaa aaagcaatat aatcaatatt tttctagttt
    34681 gttgaataaa catattgaag aaggacttga tcatgatttt ggaaaagatg aatattgttt
    34741 atattgcgaa cgttacaatg aaaaaatgtc tgaatatcta cagctgaaaa aagagataca
    34801 gaaattagag aaaaaagtac atgcttggaa gtataaagat tccaggtctg gttatgttga
    34861 atctcaaaat aagccaagaa aaaagaagca agcgtatgtt ctaaagatgg taaatgggga
    34921 agagttaatt gtattagcgt acagtgaaga agaggttcga gaactcgttg aaacacctgt
    34981 caggaaaaag gttgaaacaa taaatgagat agacgacagc caatacaata gcatctatat
    35041 tgaaacaagt catggtggat ataagaaatt agcaactttc cttagaagtt ctaaagttgg
    35101 gataatttct aaaaaagaca taagtgctgt taccgatagt ttttgtactt tatctgttcc
    35161 taaagcttat ttccaatacg atagtaaaag atttgaacgc ttagagaaat tctgtagacc
    35221 gtatactgta ttgaaaacta aaaaatttaa taaaactaaa agagtttcga tacagttacc
    35281 gactggtcaa atctcattag gtgaaaaaga ctatctgata aaagtaggaa aagagttaat
    35341 tataaaagta ccggaacact tatttaaaga aaattttgag atacgtgaaa ccttggtatg
    35401 gaaagaagaa aaatagtttg gaagacatag aatggtataa ggggaaattg aaatggcagt
    35461 aaataaaata ttgcaggtat taatcataga cgaatttggc ggaggagaat ggtttgatgt
    35521 gcagtccata gactttgaag aagaagtcgt agttatagaa aatatttacg gcgaagtata
    35581 ctcatattcg cttgaaggtg agaatgttga ggatctacgg ttgattggtg agtagaaaaa
    35641 agcagaaata tcaaaatgga gataaaaatt aatagcatgt aaagatagtc atgcttacat
    35701 gctttatcca aaatggtatg cagacaaaaa tatagctgaa ataaacgatt atctaactag
    35761 tataaaggaa cgcaatgcaa ttaattaaca atagacgaaa aatgaaatta aaggagatag
    35821 gaaaatggta gaagttgaat ttggatcaaa agaatggttt gaagagttaa actcaatgat
    35881 taagttccca gaaaagttta ctttttacta caataaaaga gacaatatca ttcaagtagc
    35941 tttacttgaa actaagggaa gattagaaaa tactcgatgg agtatgataa aaccatcggc
    36001 acttagattt catcctaaag acttgacagc ggttgtagcg gtaaaagagg ttcaagactc
    36061 acaagaatat tatgaagtag taaaaaatct gaaggatatt tggtgtaaat aattctaaat
    36121 tgaccagtta tttggtcaaa aatagtatgt gattatttca tccaatgtgg catcataatt
    36181 ggtatggaag gggataaatt atttgaaaga aatagaaggt attaagaaaa gaaatcagga
    36241 aagattggaa ctgttaaatg aaaatagaaa tagaatgttt agttattatg aatctatgag
    36301 gtgtttaaat aaatctagaa gtgaaattat agaatcatca aagtataaac aattgatgga
    36361 agagagagtt tctctcatcc aagaaataga aacagagtct atttttccag atcattctcc
    36421 taaagtccga ttttataatt aaacattaac aaatgaaacg atgctaaata ggcatcgttt
    36481 tttatctatt tataaaatta atttatttac aaaatgtgta tcggtatgta tggtgaattt
    36541 gtagataagt tgagaaaggg tgatcttaaa tgaaattaga aggtagctta caaaatagaa
    36601 tgatggaagg cagtacaaca aacaaggaga ttgtagttgg aatgggagca accgagcttc
    36661 tatataccga cagaaatcct tatacagtaa ttgaagtaaa aagcaaaaac agaattttgg
    36721 ttcaagcgga tggagcaatc aataaagcta cttttccaga tcaagagtgg gaatatagca
    36781 gaaatcctga aggtcaaata ttggagttag ttaagacaaa aaatggatgg aaagtgctta
    36841 aagaagatat tcatttttat ataggtgata gagaaaaata ctacgatcct agtttttaaa
    36901 caacctgaag atgagcgagg ttttatcctc gctcagaaag gagtatggag gatgttcagt
    36961 caagaagaaa tcatcagcaa atcgcaaccg gataaaaatg gaactataat catgaagaaa
    37021 aaaatccctt gctatcgttg tagcggatca ggtcagtaca agtttatgtc tatggggaaa
    37081 attacctatg gcacatgttt taagtgcgat ggtgatggat ttcttgttgt aactgaaaaa
    37141 tcctttacgc cagaatatag aactaagcta aatgttttaa ataaaaaaag agctgatcga
    37201 aaaataagga tcgcaagaga gaaagaatct cagaaaaatt ttgatcgtta tggctttgaa
    37261 aagggttata tttacgtggt tatagagaaa aatagctata cgatcaaaga tgaactgcat
    37321 catcaaggag ctacttatga tcctttatta ggttggtttt tttaaggaaa aacaagaaca
    37381 atacaaaact caaaaagttt ttgtagaaga attttctgta atcaatgatg aaggaattat
    37441 tgagttgaag ctagaagaat acagcaaaag acaacaggag attttaagtg cgaagcgtag
    37501 agaagagggt gagtttattg gtacaatcgc tcaacgattg gaattggatt tgaaacttac
    37561 caataccgtc accatagata cacaatgggg caatgtttac ctgcatttat ttgaagatca
    37621 aaaccataat tcattgattt ggaagacaaa taaatttctt tattatgatg aatgggatgt
    37681 tggagaaata agaaaagtta aggcgacaat aaaagcgcat gactactaca gagataccaa
    37741 gcagacttgg attaaaaatg ttaaaattca aaaaaatgag taagaaggga taaaagtatg
    37801 aaaagagaag aatacaaaca aagattaaac gaactgcttg aagaggacga aacattaact
    37861 catggttcgc cggatgaaat tctatacatg attgataata tggtaatttt tggtggatat
    37921 gaacttggta ataggtcagt tgatcataat attttagaat ttgatgatgt atcatgggaa
    37981 gaaattcttg attggggaat tttggcagta cctgaaacta aaacctatat tagtgacact
    38041 atggttcctt tttttgagga attggattat aaaagacttc ccaaaaatga aaatcatata
    38101 ctgggaggaa actaacaatg ttaagtgact tacttatttt actgatctat ctaggtggaa
    38161 ctgaaattat tgcgtatttt ttgcttgtaa ttggtgaata tggtatttcc agtgcaatca
    38221 ctcaaaggtt tagattacca gtaagtgaac taaaaaaatg atgagattat cagcatatct
    38281 tttaatgttt ttgaatgtgg tcatgttaat ctttgtagta atcggtgtga ctttcaattt
    38341 aacggaatag agggaaatct ataatggaaa aaagagaaaa gaatgaacat attttttgag
    38401 tcaatattgt tgatggtttt tgcgatcagc gcttaccaga aatctaaaaa agagtaatga
    38461 ctgtttagtc atcactcttt ttttgtaggg aaattgaaat atgtggagct tgtattggtt
    38521 tagttaggat tgcttggcta taaggagcta gttctttatc aaaaccatca aagtaggttt
    38581 tcagtagcga tttaactgat cgctcatctt gtttgatttg gataatttca gcatccaaat
    38641 cggttgtgag gtcaggagct tttgaagcga ttacctgatt ttttttatct tccaactttc
    38701 ttaggctgtt taacaagttg taaaaataat cattttgact gttcattcca acgtgagatg
    38761 caattttaac agaagtttca tccgtattgg catcaagtat ttcatcaaaa gaactcattg
    38821 gaatatcaag tagtaacgag gatgtttcct ttacagcatt tttagttttt ccatcttttt
    38881 tgctcttaac ttgagatatt tttggatcta gtttaggtaa atcacttgtt ttatcagtca
    38941 tttattagct tttcctttct attaatttat gttattatat tatcataata acataaaaaa
    39001 gtacactttt tgggggcgta gttattgaaa aaatctaaga gaaagattgc cacgttgctt
    39061 acgttaatgg tgcagtttac agggattgca atgagtgtaa tcacaataaa tccgcaagtg
    39121 ttacatgctg atgggatagc tacttatgat gcacaattta actgtactac tgaaggtagt
    39181 gggtcaggaa cagatagcga tggaaacgat actggaagtg gcgctgtaac aggtgatgta
    39241 gccaaaaata ttgaagatat ttacaaatac atgaatggag aatatggctt atcaggtgct
    39301 agtattgcag gtattttagg taactggaaa caagaatcag gtattgatcc tcgaacagta
    39361 gaagggtatt acggcgatgg gcagagagaa gttgacttca tcaaacaatt tactgatggt
    39421 ctaatgggta ttggctatgg tcaatggaca gccgggcgac atacagcatt agttgattgg
    39481 tctaagaaaa ataatggcgg ttcttggtgg actacagaag cccaattgga ctttatgttc
    39541 aaaggtgatg ggggattcgt aggaatatta aaagattatg ctttaaatgc ttctgatgat
    39601 gtagtagaaa atgcagtaac ttttcataaa aactgggaaa tttcagctga ttccgaatca
    39661 gctgtaatag ctgtacgtgg tgaaaatgca aaagaaatct ggaagtacat gaaaagcaag
    39721 ggtatggacg gtgcaaaaga tgaaagtaag atcaataaaa tatccggagg ttcaagtacc
    39781 ggagatggat cgaataattc atcaagttca gcatcaggaa cagtagaaga tgcctgtgca
    39841 actacggatg atgctaattc tggttctgga tcaattggga aagaaggaaa aattaacggt
    39901 aaaaaaggtc aagtaatagc aaatatgact tatgaagaag cattaaaaaa atatgggaaa
    39961 gcaatcacgc taccaaaatt taaagaacca gactggtcaa catcaccttt tcaaggtgaa
    40021 ttacaaggac aatgtactga attaacatgg gcttatatga gtcaattata tgatggaaat
    40081 caaccaactt tgggaaatgg cggttacgtt tgggaaagct acaaatcggc aggagcaaag
    40141 gtgacgaaca aaccaattgt aggttatgcg tttagtgctt tagatggatg gttatgggct
    40201 gttggatcag caggacatac aggtgtagtt atagcggtgt ttgacgatgg atcatttttg
    40261 tgcgctaatt tcaatgttcc acctacccaa gcaccaacaa gaggtgtttc agtaactttg
    40321 attgatggtg tggatgggtc agataatgtg catttcttta gcggtgtagg caaagctaaa
    40381 tttgaaattg aaaaataaaa atttgaatgg agggcgacag agatgaatag taaaacgaaa
    40441 gatgcaatta tcatttcttt gctttctggt atgctattag caatgcttgt tggaattcta
    40501 tatttcaata agcagaatca agacatagaa gctgaaaagc acagtgtgca aattgaaaat
    40561 gaattgacct tctttaaaga ggttaaacca aatgaagtgg atggattgca aagagattta
    40621 gaaaatgata ttcaagagat gtttaaagga tcagaccgaa gcaaatttgc gaatcagtca
    40681 ggtgaagaat ttttgcgaaa gttatttatt gtgacaggta agccaccagt tactaacgag
    40741 agtagcgagc aagaaaaaat agaatactat aaacctttta cttttaagct aacaaacttt
    40801 ggaattaaga catctagtag tgggttgtat gaagcattga ctgatttcga agttcaatac
    40861 aacggaaaaa aagtgtatga taccacatta accatcacac taaataatga taagaaagtg
    40921 actgggggtg ctttttatgc aaaatcatga aattactact gctaaaaagg cgatcggaat
    40981 actttccata attttgatcc tttgttgtgt ggtactattt caaaagaaaa atgcttatga
    41041 taataatgtc aaagaattgg aagaccttaa aagtaaacaa atcgaagtag tcaagaataa
    41101 ccagaaagtg aaagctatgc aagaagccca atacaaagaa ttgggaaatg ctgaaatcaa
    41161 ggaacaaagt aggaaattct ttaatttatt ttacaactgg aattcatggg aaaaatatac
    41221 gaagaatatg aaggaaatac aaaaagaatt tcctcagata gtaaagtcta gtcctgttga
    41281 tatctctggc acaatggtag gtactggtaa tagtccaata tctagctata ctgctgatta
    41341 ctatacaaca aatcaaaaag gtaaaatggt tgaattgatt acacagacaa gaaatactcc
    41401 aacaacagca acaacaacaa tttggcgtgg agtaacaagc ataggagaaa atcaattgtt
    41461 ttacttggag gatttagata gctatgtaag agcagagtaa aataaaaaaa gagctaacgg
    41521 taccaacgtt agctctttgt gctgacgatg ataacaaaac ctaccgaaaa aggattgttt
    41581 catcacaaac acaaacagaa aagaattgat aaaaaacccg aacctcagaa tttttattaa
    41641 tcaattcatt ttgattataa taaattgagc tgaacattac aatacgtata tgttgtaaaa
    41701 cgtaaaaaaa gtcaaaagta aatactttct taaaaagtca aataaaacta ttaaagacaa
    41761 tatatatggt ttatttgaca taagaaaatg gtctagatga taattagaat atagaattgt
    41821 agacttaaat aaatcataaa aaaccttcta tgataagtta tagctcttaa ttttaagcag
    41881 ttttagatat aagaaagtaa agtgggggag aataataatg gcagatcgta aattagaaaa
    41941 gttattagaa gaaacgtggg atccaaaaga atttagtgaa ttttttatgg agaattttga
    42001 aactgactta gcggtgattg ttaaagatgc tcttagagag caagggtatc ctgaaactgc
    42061 aaattatata aacattaatt ttactttgta tactgaaaat agaggaactt gggatttttg
    42121 ggctaactta gcaaataagg agttaagtga taaatcagat acaggaattc gtaacttttt
    42181 tgaatcaaac agagatgatt atatgtacgc taacaatcaa aataaattga actttagagt
    42241 agagtttgat gaaacacctg aagaatttat agaaagacaa ccgcctaaag aaaatgtagc
    42301 aaaggtattg gaagatcgtt ggaattcaga tgaaatagtt tcaacaatta gcgaacaaga
    42361 cggacaatat gaaccgctag tagaagcggt tagagaagag ctaagactga ataagtttcc
    42421 tgatgttcaa aatattgatg tttctcaaat tgaaataaac gtcaatatca ccaatagact
    42481 tgattatgat agttgggcag atatagcatt agaaaaatat atttactcaa cgttaaaaga
    42541 gtttatcgaa aatagaatga atatcatgta tctacagcat ccacagtatt taaactttgg
    42601 tgttgaaata gctacacctc ttgaagaatg gaaaatggag caagggcttg actagccttt
    42661 gctccatttt tttattttac aaatgaatac agttcttcgt ctttaccaag aatgattgtt
    42721 tgcccaactt tgagattatc aggtgatcct tcagcggttt gtaaggagaa cgttccattg
    42781 aacttatcgg ataccgttat aggtagcttt aattctgatc cttcctcatc tttgagaatt
    42841 gctgttttcc gttcatcaaa ataaacagtc tttattagat aatttttagt agtggtttca
    42901 tcagatttgt ctttgttttt agtagtacta atttctttag aattagatgt attttctatg
    42961 actatttcgt ttttggtatt tgcgcttgta tttatttgat tgaaaatttt aatcgacaag
    43021 atcccactaa gaatagccaa catagaaaca agtgtaatta atactgataa tttccttttt
    43081 ttgttcattt cttcttaact tccttttttg ttttgattag ttagatattc cttatctaat
    43141 aagccttttt aggctattaa atgaagataa accccaaaaa attattgcaa taatgatagt
    43201 gcaatggtac tattattata aaataaattt tgcgaaaggg gtaggtctaa atcgcaaata
    43261 aaaagaaatt gaacctagac aaatacaact tgtataccgc aagggaagca agtctaattt
    43321 tgggtaaagg tagaaattat gttacaaaca taatcaacta ttatccaaat cgtttgccta
    43381 aaggttcgtt caagaaagtg ggtgacaaaa cctatattat aacggaagaa ggaatagaag
    43441 cattgcgatc acaaacagaa aataaaaaca aaaagaagga atgaatatga agaaaaattc
    43501 gcttgctatg gttttatttg catcagctgt acttgcgggg ttatcagtac cagtaacctc
    43561 acatgctgat gaatggactg caaacacacc ggatcaaatc caaattacaa caggacaatc
    43621 aagttatgcg ttcaaaaaag gagatactat ttggtcaact gtagagaagc ttaaaagctt
    43681 aggttacaag actactgttg ctgagtttgc cgaattgaac aatgttgatt tggcaaaagg
    43741 agaacaacgg actatcccga ttggacgaac tttcaacatc aataaagata cattaacagt
    43801 taaggaagca gatggcgaag tagttagtca aactgttcaa aaagataaac ctgatcctgt
    43861 tgaaaatacg gagcaagaga acaaaaaatc cgagactaca aaagaatcgg aaccaacagc
    43921 aaacacttct gataagacag aaacaagtgc ttcaagtgtt gatggagcaa gttcatctaa
    43981 tacaaataat tctacaagtg agaaagaagc atcacaggga acaagtgaaa gtagcactac
    44041 ggaagctgat actggaacat caacaaataa ctcacaatca acatcaaatg atgcaaatga
    44101 atcaaccagt acatcttcta gtgatcaatc acaaacaggt tcaagtgatg aaactgacag
    44161 ttctacttca ccaagtaacc ccgaacaacc aactaatgtt gtgctaggcg ttccatttat
    44221 tagtcaaggt aacacaatgc tttgcgaagg aacatctttg ctagaagcgt tacattataa
    44281 aggtgttgca acaaatcaag atttaatgac ttttgttaaa tcaatgccac tatctcctga
    44341 taataatcca aataatggtt tttctggtga atggagacac aatgtggatg gaacttatca
    44401 aggtatgaat ccggctcctg tagtttcatg gggtgttgct aatggcggaa atgttgtaga
    44461 tatttctggt tcatcggtac aaggattaaa agatgagatt gtaaatggaa atcctgtagt
    44521 agcgtgggta acttatgcct ttgaacctgc tcaacataaa tcaatgtttt ggggcgatgc
    44581 tatttggaat cgacatgtag tagccgttga tggatttaaa gacggttttt accatgttgt
    44641 cgatcctgtg tttggggcaa gttggattaa tgcaggatca tttgaaacag catataacgt
    44701 atctcaatta gcggtttcgg tacgttaata aaagagatcg tttatatact aagtagttaa
    44761 gtatagtctt tatttgtcct tgcttaacta cttagaaaac ttgttgctca tggttggtag
    44821 aactaaaagg ggtgatgcta tgagtactag agcgttgaaa cagcttgctt tcaacgaaaa
    44881 aagtgattaa taggtgtggt gattttaact taggaatggg cgcgaaggtc attaccacac
    44941 cgacatatcg tggctcattt tcttcgccta actggtataa agaaggagta acgagagatg
    45001 aagcatgaaa aaacgataat tttaaaatca aaaataattt attgttttgc gactttagta
    45061 atggtgttat ctacgcttat aatgcctttt tcagcaataa gagctgaagc agatgtcaca
    45121 aaaccgacaa gtgcaaaatt tacagaaact ggcgtaaaaa cagacggtta tattagggtt
    45181 aatatgccga atcatccaaa tgaatggatg atttcaagtc aatttaaaga ttctcatgga
    45241 aatattggat attgtatgga ttcagaattg ccatccccaa caggaagtgg agccggaagc
    45301 ttgaagtaca agggagctgg cagtgatgag ttctatcgta tgtttaaagg tggttttcca
    45361 tcaaaaacag caaaggaact gggtgcagga aatgatacag aagcatggta tgcaacacaa
    45421 ttagtttcat gggttttagc cggaaacttt aaagtttcac agattgtatg gtcacatcca
    45481 aaccataccg ccgcagaaac agctcgtgta aaaaaagcat ttgaaaaaat ttatgactat
    45541 gctaagaatg gaaaagatac gcccaacact gagttttcta tcacagcttc taagacagct
    45601 gacgaaggaa aatatcacac tttcacatat aaaacagcat caaataagac tggtaatgcg
    45661 aagctcactt ttacatcagc aaaaccagct ggtatgaaga tttatgatgc agatggtaaa
    45721 gaaattacta acaacactgt gaaattaaat tcaagtttta ctattaaagt acctgtgact
    45781 acaccaagtg gtactttgtc atttaaaggt actgctaatg ttagcacaac caatcctttt
    45841 acttttgatg gacgaggtgt gtatcaagat gccgtagtta tgatcactac ttcagaaaca
    45901 aaggactcta aatctttgag tgctaaatgg acaagagctg ttggtcaggt aacagttaag
    45961 aaagttgatc aagatggaaa tgctttaaaa ggagcggagt ttactctaac tgacaataac
    46021 aatgctaaat ctgttaagac aaccggagat gatgggttag ctacgtttga tttgcaacaa
    46081 ggcttaacat acagcttaga agaaacaaaa gttcctgaag gttatcaagg ttcatttaaa
    46141 aaggatggta ttactgttaa taccgatgga caagaattta gttacactgc tacgaacaca
    46201 attaaaaaag gtaaagtaaa agttaaaaag gttgaccaag atggaaaacc attagctaat
    46261 gctgaattta ccttgacgga tgattcatcc caaacacaag cagaaaaaac agatgaaaac
    46321 ggacttgcaa gcttcgatat tgtagcaaac aagacctaca gccttgaaga gaccggagta
    46381 ccaactggtt atacaggcgt attcaagcaa gaaggaatta ccgttaaaga tgatggacaa
    46441 acttttgaat atacagctac aaacactttg aaaaaaggtt tagtaaaagt tcataaagtc
    46501 gatcaagatg gaaaaccttt ggcaaatgca gagttcactt taaccgatga aaaaggtgca
    46561 acacaagtag aaaaaacaga tgaaaatgga cttgcaagct tcaatattgt agcaaacaag
    46621 acgtatagcc tagaagaaac tggagtacca gtaggttaca caggtgcatt taagcaagag
    46681 ggtatcaccg ttaaagacga tgggcaaact tttgaatata cagctacaaa taatttgaaa
    46741 aaaggtgtag taaaagttca taaagtcgat caagatggaa aacctttagc agatgcagaa
    46801 ttcaccttaa cggatgaaaa aggtgtaaaa gaagttaaaa agacggatgc aactggtctg
    46861 gctacgttca acattattgc gaacaaaact tacaacttag aagaaacaaa agtaccaaca
    46921 ggttacacag gcgcattcaa acaagaagga attaccgtca aagatgatgg acaagtcttt
    46981 gaatatactg ctaaaaacac tttgaaaaaa ggtgtgatca aagttcataa agtggatgat
    47041 caagggaaag cattagcaaa cgcagaattc actttgacag acgacaaagg tgtaaaagtt
    47101 gtacaaaaaa cggacagcaa tggcttggca acatttaata ttgttgccaa caaaacgtac
    47161 aaaatcgaag aaacacaaaa ccctaatggt tatacaggga aatggtctaa agaaggcatc
    47221 accgttgctg acgatgaaca aacctttgaa tatacagtaa ttaatcacct tgtacctgaa
    47281 acagtaagaa caggcggaat cggtacatca gccttccttc ttgtatttct aattgcagga
    47341 ttgagtatgg tgctactgta ttatcgagaa cagcacaaag caaaataaaa aagtgttaat
    47401 ggaaaagaag taaatatgaa aaaagaaggc tgacgtatga aatcaaaaaa aattttttca
    47461 aatttaatgc tatttggtac tttgctagga gtgggattgg gcgcaagctc aatctcttct
    47521 agccttggac taggggggca agtagcatat gcacaacaaa actataatta tcaaggaact
    47581 ggaacgattc atatccataa agtaacaaat actaatgggg atgggaaccc tgtctcagat
    47641 attgataaca aagggaaaga aatagcttta ccaaatggtg taaaacctct tgaaggcgtt
    47701 gagttctctt atgtgaaact tactaaagat gaagctaaat ccttgggatg gacggatagt
    47761 gatactacaa aaggtcaaca tattgatgat gctaaagcac gattattact aaacaaaaaa
    47821 tacagtgaag taagtagaat gaagactgat tcacaaggga atatagacat acctatacaa
    47881 gtaaatacag acgatttaac agataacttg tatttgattg ttgaaacagg aacagtcaaa
    47941 ggtgtagttg aagaagcgta tcctatgatt gttaacgtac ctgaactaaa cggatcagat
    48001 gatcaatact ttaattatga tgtacatgtc tatcctaaaa actatttcca attaaactca
    48061 gcagagcttg ataaaaaaga cgaagatgga aaggctcttg ccggaactgt ttttgaattg
    48121 cgaaaagatg atggatctga tcaggttgtt ggaacttata aaacagacag cacaggtaaa
    48181 ttaactgtag atggtttgga attaggtgac tattatttcc tagaaaccga cttgggaaca
    48241 gatgctaata aaacaaccta tttactagat ggtaaaaaat tcaaatttag cgttaaacgt
    48301 ggggagactg ctaaagtagt tcttgatgtt accaactaca aacgacctgt aattactaag
    48361 gtaattgata aagaaaccgt tgatactggc gaagatgttc aatatacatt gaaaccatca
    48421 attcctggta atattggtaa ttacgaaaaa tatgttgtca aagatgttct aggtgcagag
    48481 ttaacttatg attcatcaga agtgatcgaa ggaatgactt tagatactga ttacagtatc
    48541 gaacgtgacg gacaaacgac aaactatgtc tttactgaat caggtatgga taagcttcag
    48601 aaacaatttg atgcagggga tcgcttcttt acaattttga tgaacgctca tactaatagt
    48661 aaagctaaaa tggatacacc acttaagaat gatgtttcaa cgatctacaa caatggatat
    48721 gaacccgaag acgaaacacc agttgatcac gcttatacaa tcattggtga tcaccaattc
    48781 attaaaacag atggagatac aagcaaagca ttgagtggag caaaatttgt agtgaagaac
    48841 aaaattgatc cgaataaagt tacttaccta aaacaagatc caacaacgaa agctgttact
    48901 tggattgcag ataaatctaa agctactgaa ttcgtttccg gatcagacgg taagttccaa
    48961 attgaaggct tgcaatatac ctatgatgta gattttgata aacaaggtaa tccaacaatc
    49021 acagataaaa aaatcaatga ttatgctctt gaagaagttg ttgctccttc aggatataca
    49081 ccaactagaa atgatgttcc atttgtggta tcgaatgatg atgcttctag cgaagtaaca
    49141 gacatcaaga accttaaaac acctgaaaca gttcgtacag gtggaattgg aacagtagta
    49201 tttctagtgg ttgcaggtgt ggcaggaaca gggctatatg ttgtctacaa acgagaacaa
    49261 cacaaagctt aatgaaataa aattccctag agtgtttttg gctctagggt ttctttttaa
    49321 aaagtgtgtg aaaagtaggt atgagcatga aaaagaagaa tatcaagttg atcatcttaa
    49381 aaattgggat gttgctatgt ttaggagtag gtctatatcc tgtaattact caggcttata
    49441 cctactacca aactcaacaa acactaaact cctataagga aaaatatgat gaagcttctg
    49501 aaaaggagaa tgaagaagtc ttcaagagat attcagaagt taataggaaa cgaaaagaca
    49561 cagaacaaac ctcagtcacg attcctgaag ataataacaa tattccgtca aatgtaaatc
    49621 ttcagaagga taaattaggt gaattagtgg gtgaaattct tataccaaag attaatgtgg
    49681 atttgccaat ttatgatggt gtaaacgatt ttcaactatc agcaggagca ggaatattaa
    49741 ccggaactga ttatccaact ggtgggattg gaaaccattc tgttatatca gctcattcgg
    49801 gcattcctaa taaaaaatat tttacagatt tagagttgct caaacttggt gataaatttt
    49861 ttattgatat ttcagggaaa aagcttgctt atcaagtaga tcggataaaa acaatcctac
    49921 caaccgaatt tgaggatttg cttcctgtgg caggaaaaga ttatgtaaca cttatgacat
    49981 gtacacctgt tggagataat tctcataggt tactcgttag aggggttagc ataccttacc
    50041 aaaaaagtat tgttgagaaa gaaaagaaga aagaagattt aaaggtaaag gcgcagatga
    50101 actggtatca tatcgtagtt gtaggggttt tattaataat agctgtgata gtcattatta
    50161 aaaaaatagt agcaaagaga cgaggaatga aaaatgaaga ataaaatact actttttttg
    50221 actcttattt gcactttggt tttaacaatt tatcctgcaa atcagctcta tcatcaattc
    50281 aaaacaaaag agaatgtggc ggaaatccaa gagaaaattg agaaaaaaca aactccttca
    50341 aaagaggaag tggcaaaaaa agtcgaacaa ataaaatcga acagcggtaa ccaaggatta
    50401 gacaatactc agaaaacaga cggcggatca tttgatattg gtgaagctga aggaaaggtc
    50461 aatccttaca caggagatgt tttttcaaaa aatcaaacga aagattttga accatctacc
    50521 tattcagggg cggttggtta tgtctatatt ccaaaaataa atgtgctaga gcttttgttt
    50581 ctaggcgctt cacaggaaca tttatataga ggtgtggcac agatgagtgc tactagtcta
    50641 cctttatcag gtaaaggtca tcaaacagta atagcaggtc atcgtggcgg ttatacgtca
    50701 ccacaatttc tttatgttga tcaattagta gccggagacc acatttatat agattatctt
    50761 ggtgaaaaag cagtttatac ggttttccga acagacgtta ttagaaatta cggtcagaat
    50821 tcaacactga ctgatattcc tgatttagat atgttaacac tttatacttg tcatccatat
    50881 cctcagaact acgatcgttt attagttaga agtctaagag atgaaaaagc aaaatacatc
    50941 acgccacaag taacagttgg caataccgca tacgctgatg ccattgatag cgagtccgtt
    51001 tcagataaga cagaaactgt tacatcttct aatgatttat ttgaggatgt tgatcgtgcc
    51061 aacaaggaat tagatggaaa taatgatctt aatattccgg aacaaggtag cgtagagatg
    51121 caagacagaa catttgctga aaaggcaagt tcaatattca caggaattac caataaacat
    51181 cagaaaatgc ttttagtcat ttggactgta ataggagcat tagcaagtct aaaggttctt
    51241 attcttttaa tcaaagagtt tcgaaaagca taatgaagat tataaaaatt gatagagtac
    51301 agtaaaaagg gattgatact attattgatc tcttttttat tttgaataga gctagattca
    51361 cttttaaata aaatcaaaac tgattttaat tctaaagaaa aagtcaagaa aaaaatacaa
    51421 caaatttttt tatcagaata tttatcagaa tattattaga aaagataaac tcaaaagctt
    51481 aatttaatag ggttattggt tgtatttaga aataatgtat ggaaaagcta taaagaaata
    51541 gataagatgt agaaaatctt atttgtgaat gaaaaacaag tcatcgtaaa atattaatag
    51601 gaggtgtagt aatggtggga atatcaaaaa cagctttaga ctcattagct aaactattta
    51661 gtagcaggtt tgatagtgca gaatttgttg aatatctaag ccaaaacgaa agtggaaaaa
    51721 ctctgatcga aacaatgaaa aaagactatt tgaatgaaaa tgactttccg acatggacga
    51781 atattgaaga tgctacatgg gatgtagtgt gtacgatata ttctccttgg gtaacgattg
    51841 ctgattttgt tttagataaa attggagggg atacataccc tgatgccaaa tctcttgcta
    51901 caagtgactt taaaacgttc tatggttatc taataggtct aataggcaat ggaatagatt
    51961 tgaaagttac gccaaaacaa acacctgaag aaattgaaaa agaaaaagga gaggttcaaa
    52021 tggcttatgc aaatgacaga gaaaaagtaa aattattgga aggtaaatta tctgaagaag
    52081 aacttggaaa aatggtgcaa gaaatcaatg aagacagcaa ctattttcct gaattgaagg
    52141 tatatcaaaa tgacgaagat ttctttaatg aaatgtttag taatagtcca tgggaagcag
    52201 tgagtaaaac aaatttagga gaatggaact ttcaagatga tctagttgca tttagcaatg
    52261 atgggtattt acgatcatat tcagaaagtg agtatagagc tgaattaaaa acgtatgaaa
    52321 cggatattct gatgagctat ttaaatctat tagagagtgg tcagggagag ttaagagata
    52381 aagttgaaga actattaaaa gaagagctat agggattatt tcaacataaa cacaagcaga
    52441 aaactaccaa acaaaacgta ccatgcaaaa agtcggttaa accggctttt tgctctatta
    52501 tgagaggaga tcaaaccatg agtgcaacaa ccgatatggc tttagaagca gtaataaaag
    52561 ataatacagg aaatgtcgaa aatgtagaag actttagcga tattgcaatc aatctttcag
    52621 catggatttc agctgtagga gaagaaaata tcgaatttga gatcaagaat atggatgact
    52681 taaaagcaaa atttcctttt atcgcttcga aactaagtca atttgccgag gataaatcgt
    52741 ggaatgaatt agttagtttt tccgaaaaaa tttatgatat tacgcaagaa gatgagtgtg
    52801 tttcatggga aatgaataat caatacaaga aaattgatgc tttcgtcaaa tcacgtatag
    52861 aaggaacagc ttttgagttt gaaggtatag ataccgcaga taattggtta aataaagaat
    52921 cctttattaa aagtatagcg gatgatcttg aaaaacaatg gtctaaggaa gactatgcag
    52981 agtacctaaa aacagaaaga gatacagagg tgaaagaaaa actcactgag gtatgtttgg
    53041 atgaacatat tgatcccaat atcgtaaaac aagaagacta tgaagtggtt attgataaag
    53101 ttcctactga ttttgaggaa gttgtaaagt atatagttga agaagcatta tcgcaatact
    53161 cttcagatga ggaagtggac gaagaaactg ttcgtaccag agtttggcaa ctggtttttg
    53221 atgacaaaga ttataaatat ttgagtgatc aaaactcggt taattggagt gtacgattat
    53281 taattgatca aaatgatatt gaataaaata gagctgaaaa gctctatttt ttttgataaa
    53341 aaaactagct atttttttaa aaataatttg gttcaaaatt tattttttta acttgataat
    53401 tttttgccat ccttttttaa attggctata tatcaaggtt tatagtgggg ataaataaaa
    53461 atacatttga caaaatttac aatatagttt attatatatt tatcttatta tgataacaca
    53521 ataaaaggaa tgatggtatg aaaaagaaga agtttagtcg atcgttgtta ggaattttag
    53581 ttttagttgc ggttggtctt agtggcaagg gttactttca gaataacagc actcaggaac
    53641 atgattttca gatcaaaagt agtgttcagg taggtaataa agcagacagt gaatcaaaag
    53701 aatttttagg gatacgttat gatccaaaca aatatccaaa taatatcgta aacattaatg
    53761 atgggaaata tacactgaca aaagaagacc atgaagcatt atcagaaaaa ggcagtcaaa
    53821 ccttttgggt aaattatgca gatttagatc aacttggaag agcaggagat gttgaagcgt
    53881 tgatcaccta tgatgctata aattctcact catctaaaaa tgtggaacgt ccatctttca
    53941 aaagttctgt ccatattgca ggagaataca aggatggagt atttgatcaa gagagagata
    54001 cttgggtcgg caaagattca aacaatgaaa tcactcagct agaaggatat aaaggttatc
    54061 tctataacaa aagtcattca ttagcatggt cgctaggagg agatatggag gtacacaatt
    54121 taacacttgg aacgagagcg caaaatgttg ggaaaaatga tcagaatgga gggatggctt
    54181 actcagaaac gattgtacgt gatgcaatct ataaaaataa gaatgaaaaa gtattgtata
    54241 aagttgatcc aatttataaa gggaatgaat tggttcctcg tggttctcat gtcgaagctt
    54301 tctcagttaa cgataatgga aaaacggtaa accttaatgt ttatgtattt aacaatcaaa
    54361 aaggaatcaa catcaactat caaaatggta cttgggtaag agattagaaa ttgagaaggt
    54421 gaagaattgg aaacaataag catcaatgga ttagataaat cagttgcaaa tcgaataaaa
    54481 aaaggaaatg gctactatct tctgaagaag ggtaaatatt cagttgctag agagttagaa
    54541 acaatgagta tcgtgtatgt agctaagaat cattttgacg tagaacaggc tatttttgat
    54601 ccagattctg aaatagggaa atgtgttgaa ttatcagaga aaactgttag tacaaaaggg
    54661 gcgatgatca ttgagagaga aatgttagac gaaatcagag taatcattcc taaagatacg
    54721 cagatgtgtg aggacagcat aagtgacgat gaaccaaaat cagaaagaaa ataaggagat
    54781 attcagatga gcgaaaaatc cattgaatta aaggaatata agcgaagcga tggagaaaaa
    54841 tattatcctg tagccagttt ttctaaatca gtatatctgg ttggacgtgc attggtagtt
    54901 ggtgcaattg gcatatatat tttgcattgg gtaacaaagg ttgtacaact gcttgtagat
    54961 accttagtaa gtattcttgt ctcgttaaat gatgttaacg gaacagatga tttaggatta
    55021 aaagaaatgt ttaaagagtt actcaatgcg ttttttccca attatttaag ttattcatat
    55081 aatgtacaaa gcttttttgc aaagctacac ttggtagaca tctctatttt agtattagaa
    55141 gcaggaacgg tattctttgt tggatatttg gttactttga tgttcaggca tcactatgga
    55201 gaacaaagac cattttttga tgatatggaa agtagaaggt tgaaaagaga agctctagaa
    55261 gctatggatg tgaagtatga tccaaacaag attataggag atgaaacgaa caacaaaaaa
    55321 agaaaacgaa acaaaacgca attagaatcc gatgtgctat caacgcttaa aaatatcaaa
    55381 atttctgttc atacaagacg tgatctaagt gtcaatgaag atattcgaga atatatcgta
    55441 aaaatcccgc aaccaaaagg gaagaaagtt agagaaacag ttttacgaca aattcaagat
    55501 ttagggtcga tcctgacaag agcaacaagc ggacgagcca aatttggtga aaaagaagat
    55561 gaagtttcag gcgattattt cattttccga gcatcagtaa atattgaaag agaacgtaag
    55621 gaaagagtaa gtaccaaaaa caaagaaacg gaaagagcaa catcttcaat cgcagtttca
    55681 aattcacaat tttcttttcc aatcaatctc tttgccgata attccaaaaa tatccaaaac
    55741 caaaccgaaa aagctagaaa atatgccgaa actcaaaagc aatctttaga actttatcta
    55801 tcttctgctg acgtacctgc aagtctaaca gatatgcacg ttgggaatac atctattgaa
    55861 tatttgttta ctttatctcg taccagaaaa attcaactaa gctcaatgaa agaagaaatt
    55921 gaaacttact tgcatatatc aggtgtaatc gtgcggatca acgcagggcg tattcaaatt
    55981 actctaccat taggagaaaa tgatcgtatt ccaattgatg taccatcaat gatcaatagc
    56041 gtgttttaaa agacatcaca aatagaaaca gaaaatacaa actaccagtt cacaaacaga
    56101 aaagtaccga gaaaagtgag gaatagaaat ggctatgaaa ttattagaga aagtcaaaaa
    56161 gagagccgaa aaagctgaat ctattttgct agataaagaa cctaatataa agcttaatgg
    56221 aaaattcagt gtcaatatgt tgaacacaaa ggctaaagac ccgacagatg ctatttttgg
    56281 aattaagcct gatggcacaa ttgctcattt ttgcatcagc gaaatgccac acatgttggt
    56341 tgcaggaacg acaggatcag ggaaatcagt attactgaat gaaattcttg ttacagcaat
    56401 gtgtcactca acgcctgatg aattaaaaat aggaattgta gacccaaaaa gggttgaatt
    56461 tggaagatac aaaaaattgc cgttcatgtt ggctgatcca attacagata tggatgaagc
    56521 ttatgatttt tttgaatatc ttgtgatctt gatgcatgaa cgttacaaac tgatggaaaa
    56581 agcagggtta caaaacatca cgctatataa cgaatatgcc gaaaaaaatg gattagatag
    56641 atttccctat gtgatcttat tagttgatga atattcacag ttggttggaa cacataaaga
    56701 agtagaaggt ttgattgttc aattaggaca aatggcaagg gcagcaggta ttcatgttat
    56761 cttagcaaca caatctcctc gatcaacagt tgtcactggt attatcaaag ccaattttcc
    56821 gtcacgtgtt tgccttatgg tagcaagtga tttagaaagt aggattgtat tagatgaagg
    56881 cggtggagaa agtctaagtc caaagggaga tatgcttatt aagcttgttg atggaagtat
    56941 ggttagagcg cagggagctt acatcagtaa caaagaaatt gaaacaatct tcaatcacct
    57001 tagaaatact atgccagaac cagaatatgt tgattaccga gcaatcgtag ctgaaactcg
    57061 tggtgagggc ggtgaagacg aggattttgg tggaattggt aaagctcctg taagaaaatc
    57121 tgctaaaaga aatttgaaca cacctttagc aaatccatca tctaaagagc catcaattga
    57181 aaagaagagt gcgtttgcta ttaagcttga aaaaaataaa gaagaaaaag ctaatcaggg
    57241 agctaagtca ctagaaaaac ttcagcaaga aaaattagaa aaactagaaa aagcattatc
    57301 atcatcaact tctgaaactc aatcttcaaa gggtatagat aatggacaat caattacaac
    57361 taaaaacaag cctaaaaata gtaattcaaa tctctcggta aatgttgtta tcacaactga
    57421 taaatctgaa aaaaaacaag tgaacggaac tacttcaccc atcatgcaaa aaatgataaa
    57481 ggcaaaaaaa caggtgcaga aatgattatc attagttcct ttttgagatg gctaacacca
    57541 tataaatata cagatgaaat agttgagaag cgagcgaaga aaaaagttaa aaaaacgatg
    57601 ttaactccta aagaaatgct agatcgtgga atattgggag tgaaggtttt agaagtaaac
    57661 caaccgtttg aattggataa tgcgagagat aggttgctta gagctgaagt tgatgtcgca
    57721 tacttttatc atgataaaag caagcatcaa atagctatca aattcaatcc aaaatcggca
    57781 tggcgatacc aagcaagaga tgacctaaag cgtaggaagc tgaaaccgat gctctatcct
    57841 gaaggaaaag aggcatttga tagaacccat attgttccca ttggatttca tggtacagag
    57901 tcagataacc gcctattggt agggtggaac agctcacaaa atagagttca gatcaataaa
    57961 tttgagaaga aggtaagaaa atttaacgat cggaaaataa tactttggtt tgccaatatt
    58021 cagaagcaac cagatgggac agcaaagtgg gaagcggtca tatttgatga agatggcaaa
    58081 aaagtaatgt ctgaagtatg gcatgataaa gctaaatttg tttggcagta gaggtgaaaa
    58141 ttgtgttaac taacctaaaa ctatatagag agggatttaa cgaaaaagta agtatcggtg
    58201 aatctattga atatttagga aagaagtaca ttattattcg tattcttgaa attaaaaaac
    58261 tttattttag taaatataat aatttagcag ttagagttct cgtccaaaag gttggaaatc
    58321 caagtgacta tagaagtgat taccataact ataaaacaga atcatctgta attaagcgtt
    58381 ataatcaatc aaaaaatgat gagagaatat tcaaagtagg agaaattatt atttctaagt
    58441 atgggatagc atacgaaata gtttctatta aaaaatttta ttatgaattt gttgatttgg
    58501 ttgtagaata ttctgttcga ttgatcgttc cgtggagtaa agaagaaatt aatgaggcat
    58561 taaaacatga acgaaaaagt acattcaaag ttttagaagg tgaaaaaaag tgaaaacaga
    58621 ccttactagg caagctgaga agtgcttatg gcatgaaaca aatcgcatgg gtgtatttgg
    58681 ttgtttcgaa gtcactatcg gttgggatgg cagtgaaaga gtagattata taacttattc
    58741 agtagataac acagttcgat gttatgagat caaagttact ttagctgatt taaaaagcaa
    58801 ggcgaaacag acttttatcg gtgattataa ctatttagtt gttactagtg atttgtggga
    58861 gaaaatgcaa caagacgata aacttatgcg gaaatattac tatcaaggcg tatacgtgtt
    58921 caatgaaaaa tatcctagca taataagtgt taagaaagca aggaaacaaa aagtatcgct
    58981 aggtacaaga tcaactgtat tagaaagcat ggttcgttct atgaatcgtg aagttaagaa
    59041 actctataaa gtaaaaccat tttgggagat agcagaggtg gaaaaaggat gattcaaaca
    59101 tttgcaaaaa tgagtagaag tgcttggatt gaaaagctgg aaaatgattt gagtgttatg
    59161 cgattagctc caaagaaatt caaacgagag attgcagaaa aagaagcaat tttgtcggta
    59221 ttgaatgcgg tagaactgga cgaaccgaaa aagtcagttg atgtacctga aaatgtagca
    59281 gagttactag attattatcg taattcgtca gatgtcgatt tgttagctct gatattaaca
    59341 tttcacgatt ggtattactg tcaaaatgaa gatactcagc atgataaaca tgataaagca
    59401 gttgactggt taatagagaa tccagaaaag ttcatgcgtg cttggctaga tggctatgat
    59461 agcaagaaaa agccactgga aagtaatgag gaaacgtatt taacggcaga acaatatgac
    59521 tatgctagaa aaacaggaga ttgggaatct ggtaagactt tcaatcacag aaaagatcaa
    59581 ccaaaaatta gtttttcaga tatagccgca attatcgaag gtatctacta tggacaagcc
    59641 gatgaagaga tcttttctat acaagattta ttagaatttt tgaacaaaaa taaggatagc
    59701 tttgtagaac taactgatta tgaggaggat acagcaaatg gaaaattatg atccaaatat
    59761 gcgatggggt acacatacgc ttaaagtttc ttttcaacgt tgggattaca agggatttgt
    59821 gacttttaga aaagctggaa attgtaaagg attagatgtc ttagcgttgg atgaagacta
    59881 tctatatgac catccattga cggataatcc aatcggattt ggattgcttc ctgaagatga
    59941 tgagggcaat gaatggttca aaatgattct tacaaacgat aaaggtgatc aattatttgt
    60001 agaagatact tggtcatatt tgagtgaata tattgttagc attaaaatca ttgattttgt
    60061 agcagataaa gaaaaagaga ttggagaagg taaatctaat tactagctaa tgaatagcaa
    60121 ctttggagga taagtcaaaa gaataaaaaa agaatactgt gtgtcattgc agggatgtat
    60181 ctttgcatga tagtatctgc ggttaccatt tattggttag gaaatcagca aaacagttta
    60241 attgttgatc tgggggagtt aaaggttgga ttacgaatga ctagatggct tttattagct
    60301 caaacagttg gtttagccat attgacttgg atatgtgtgg aaaaaataac atctaataat
    60361 aatcaagaga ttgttgaatc aacaaaccta agaataactg aacaagcaat tgaaaagcaa
    60421 aaagacaaag aaaaaaagga aataatgtca atttatttat ctagtggagc atcatttttt
    60481 catgaaatag attcgatgaa actgagtagt caagaaatca ttgatagatg gaaaaacatg
    60541 cctctaggtg gtgagttaat cgttgaagat agtgatggtt ggtcagctta taagaaggac
    60601 gagattgtag ctatcacgat tttgtttgaa tagtaatata ttaccactag ataatctgaa
    60661 tatgttgatc tgctagtgac gtaccaaatg cgtttaatag aaccttggtc acaggcagaa
    60721 attgataaag cagtaaaatt gaaccgatta tcaaaattta acgtattagg aaatgccttt
    60781 taaaaatcgc aatacacaaa cagaaaaata ccaaaaaatt agcaatgaac gtaggtaaga
    60841 acatgacaat aaataataat aaccctaaca aatataatgc tcttgtccaa tgctatatcg
    60901 aaaacaaaat tacaatgcaa gaagtcgctg atgaattagg caaatcaaaa agcctagtat
    60961 cacacgactt taagcacaat gtttttccga acccgattga gctgaggaaa aaatttcaaa
    61021 agagagttta tcaagaaata gggaagtgga ttgatgaagg gaatgcaatt gaccctttaa
    61081 ttgaaaaata tcctttttta aaaagcaaaa ataaaattca aaggttaatt cgtcaaggcg
    61141 atattcaagc taaagaacct gttttgacaa ccaatgattt ggctaaaata aatcttcata
    61201 aacagattat tgaagacttt gaaaaaaatc tttcaacaac tgaaatttta aaaaaataca
    61261 atattccgag aggaaagcta acatcgactc tttttagaga atatggagaa tcggcagtta
    61321 ctaaagcaaa ggaagtagcg aatgagagaa aaaaacaaaa atagtagtcg atacttagta
    61381 gcgactgtag tttttgtttg tgtattgatt ttcctgtttg attttttaca gattggaaaa
    61441 agtataattg gaaatacatt gagtgcaaag gaaatggttg ctttaggtgg tttgtatgaa
    61501 ggacatttgt tcccgaatat attcatttct atcgtttctc atattaactt gtaccattta
    61561 atttctaatt tattgttctt agtagttctt gaagaagcac tgaatgatca gtatgagtgg
    61621 ttaacattat tgatcgtttt aatcatatca ggatttctag gaagcttagt tccttttctg
    61681 ctacaaagca acatcgtaag tatggggctt agtggaggta tttttggatg gattgcttta
    61741 tttgcgattg catacatcca ttttgatagc aaggaacatt tattactaag tgtttttgta
    61801 ttattgataa tcggcatttt attggtatct acttttgaat caggcgaggc aaatgtcttg
    61861 tcacatgtaa tcggatttgt ctgtggaatg atcttgggat ttattctaaa gaacgtttca
    61921 ttgatcaaac aaaagaatta aaagggagtg ctaaaaatgc caaaaagaaa agaaaagaaa
    61981 attccagtgt ttttgtctgt ctcagaaatg ttatcacttc aaatactgtt aagaaaaaag
    62041 attgaaacaa tagacgaaga agttagaaat aaaagggcta tgtacgaaca acgtgaagcg
    62101 ctaagagaac gaatccacta ttttgatgat atacacacta aaatctatga agcacgtaca
    62161 aatcacgaag acgaaagtaa attaggatta gctcaacaac ggatacttga atggcttaat
    62221 acgaatactg atcaagaacc gttaagagtg attagtaatc tttttgaatt tggaacgaag
    62281 cattggttta atgctgtaga gaaggatgct gacttacaag aagcgtttga tacgctaagt
    62341 aaggatagca aatccatgcg agatttattg attacttatc taaatgagca tgagtttgaa
    62401 caaacgaaaa ccaaaaagaa aaataaagaa tagaaagttg tgatgaatca tgctattaac
    62461 cctgttaggt tatttatgtt taattcttgc tttttttggg gcaatcgcta taattattgg
    62521 tcaatttcaa acaaataatc cgattatgcg taacataggc attggaattg tgattgtaac
    62581 ctttattgtg tttaatgcca ctaagatttt tggaagtaac gataaacaat ttggtatatc
    62641 gggagttaat aatagttatg ctccagattc tttgggaagg gtagtaatag atggaacatt
    62701 tgaaaatgta acgagttata aaaatgtttc gctgacagtg aaggaagatg gcaagaaagc
    62761 atcagacgac gttctcgcta ctattaagcc gtctcaatca caatttgaag tgttttatac
    62821 agttaaagag aatagccctg tacacaagct gacattggtt tttaacgttg atggagaaga
    62881 atactataaa gatgtaaaaa taaataaaac atcaacgaaa aagattatcg aatcagcgaa
    62941 aaaagaagta gctacagaag aaagtacaac tgaatcaagt tctactgtcg aagcggaact
    63001 accagataaa attgattttg atcctgaaaa agtcaaatcg tttgaatctg tttctggttc
    63061 tatggctgat cggtttaaca ctgaagtctt caaagctatc aaaactgtta aattggatac
    63121 tgaaaagcaa atgattaatg ttaccttatt caattcagtt gaatctatgg atcaggataa
    63181 aaaagttacg gttgcaagag aactaggaaa aagagtaatt ggtttgtatc gtggtactgc
    63241 taaaccagat tcagacggtg cagatttgcc agttcatgta gtttatgaag acggtaaagt
    63301 ttttggagat tctacagcaa acgaagcatt aacgattaaa ttggctaaat agccagaaag
    63361 ttataataaa caaatggtgt cacaccaata atatataggt gtgacacctt ggagatgata
    63421 gctgatggta gtaaataaag aaaaagttag aaagtatgtg actttaaaaa tagcttctgt
    63481 taaatattta gaaaagcgag ctaaagaaga agaaagagca agaggtaaga aagtaacagt
    63541 ttcagagttg ttagaagaat tgatcgagaa tgatcaaaca ataagacgtg catttactaa
    63601 taggtctatc agataacaat ataattaata aaaaagaaag agtgatttgg tcttagacta
    63661 aatcactctt tttatataaa gtttctttac actcattccg aataatgtta aaattcttta
    63721 tatgatatat agttccttgt cagaggaaga gataaccagc aatattggag ggataataag
    63781 tggaaaacaa taatgatatt agacatttta gcattgggga aagagttaca acagtaagtg
    63841 aattatcaaa ggattataga gataaagagg gaacgattat ttctcttaat aagaatcgaa
    63901 gaggcgtttg gcaatatgtt gttgatttag gtgatggcgt tacagttgag tgtaaagata
    63961 gtcaactgat cagaaataat ggcagtcatt ccattgaaaa agcaattctt gtatacccaa
    64021 aagtatcaag taagatcatg aatgactggt tgcttggaaa atttggtgag tacaataaaa
    64081 aagaaatcgc agaagtgatc ggcaaatctt atccaacagt attagggtat ctaaaaaaga
    64141 taacgagtaa agaagcaaaa attgaggatg ttttaacagt aagagagctt caatcattaa
    64201 tcgagtatcg gaataaacaa ataacaaatc ctgagtacct tagaaaagaa gatggtctat
    64261 tgaaacaatt ggaacaagta aataaaatcc ggaagatgca aaaggtagct cctttaagcc
    64321 ttgatacctt taaaaaaatc tatttgaaag agatcaaaaa agactaatgt ggactgtaac
    64381 tttaccgttc caacctgtat ctgcaccaag accaagtgca agaaggaatg ctgctgatga
    64441 aactaatgac gtagcagaga aaaggatttc aacctactat gataaaaagt atcttgatta
    64501 tttgaaaaaa ataaagagct ttatcgaaga tcaagattta ttagatgatg aattttactc
    64561 gattgtaaat gatcctatgg gcgcaattat ggaagtggac ttttactacc agataccaaa
    64621 aagctataaa aaagtctata acattatgaa gacaacagcg ccagatttag ataatttagt
    64681 aaaaagtgct atggatggta tttttaacat ctcagctata cgagatagcc atatcacagg
    64741 cttaattgct tttaaatata atgtggcgaa cgaaggaaaa acagttgtga ggatcaaacg
    64801 atattcagaa tttgagtggg atacttctga aggattgaac ggagatatat gggaagctac
    64861 atttgatttt aaaccagtag caacgccaag accaaagtct aaatttagag gaaatgggat
    64921 tatcacttac tatccaaaag agtacaacga ctatttggaa aatatcaaga atacgcttaa
    64981 agagaaagat ttggtaaatg atcaactgaa aaaggtaatg aatgctccta tgggggttat
    65041 agctcagata gattattttt accaagtgag aaaagataag aaaaagcttg attcactgat
    65101 gcgtacttca cagccggata ttgataattt agtcaaagga acattggacg gaatttttaa
    65161 caaggaaata ggcatcaaag atagcagggt tgtagggtta attgctttta aatacaatac
    65221 ttttgaaaag tcgaaaacaa acgtgagact acaggagatg ggctgatgaa taataatgaa
    65281 aaaattcttc atgtacttga tagctttgaa ataattcaag aagaactaaa aaaatatcgg
    65341 gatgttttgg aacaaagata tgattttgtc aatcagcaaa agagtaatca catggatttc
    65401 attctcaata tgaatgactt gaagaagaaa ttagttgaac gaaaagaaca agaaaagttg
    65461 atcaaagctt actttgaact cggtgaaaaa gaagttaaaa atgcaatgga actgaatgaa
    65521 gagcgcaggg ttttagatca gctgttagaa caattattgg tgatgtttca aaaaggacga
    65581 atagatgagg atttaattga agaaggattg agaaaatatc cttcaaactc aggtatcgga
    65641 atagtgctga aagcgattga tgaagaagaa attgaagctt tcataccgcc agaggatttt
    65701 gaatcggcaa tggaatatat aaaatattat agccaaggga tcactgcttt tagagagttt
    65761 gatcctgaag atgttattca tgacttgaac aacctaaaag aatggtgtga aagttatgga
    65821 gtcgatgatt ccggattgga ctacttgatc agtattatgg aaatcgaaga agagatgccg
    65881 gataagcctg atccaacaga tattttagaa ttgatccatg aagctagaaa tccaattgcc
    65941 tatatttcta gaggatatac tgtattggaa tactataagc cttatatatc agcgatgaac
    66001 catttaagac gtgtattaag ggaaaaacgt gaataccgct cagtgttgaa tgcaacgaat
    66061 agattagaaa aagctgtttc agagctagat gcttattatc gtgaacatta cctgcaagca
    66121 ggtggtatgc caagaaatac gaaagcaaat atcagtaggt atataaaaaa agctgagtag
    66181 gcggagttag cccataaaat ggcaaaaggt aacctgaaag gggcattttg aatgaaaagg
    66241 gatgtttttg aattgtacgt attagaacgt ctagaagacg gcatgatggc acaagagata
    66301 attgatgaaa ttgatgatat gatcagcaga tttggtcaat tggagttgaa tgatggaaac
    66361 aaaaattcgg tagtgctaaa acaattttgg ttgaacaatt tttcgtataa ggattttatc
    66421 aaagaaaagg caaatacatt gtactgacta aattcacgag gagcagtgat gagagcttat
    66481 tgctaagagc agttaggctc ttttttgttt gtgtaaaatt atttgtttta taatacacat
    66541 ttatacacaa aaaaatattg acagatagta cacaaatgtg gtaggatata tttgtaagca
    66601 agttagatta acaagttaaa ggaagagcag ttatgaaaaa agaagaacta atagatatat
    66661 ttcaaattgt tgaacgagca aataatatgg gaattatgtt ttttgatcgt atttctttaa
    66721 agatggattt aagcgttgcc caccaagaat ttaatctgcg attaaaagcc ttgttgaatt
    66781 ctgatgatgt taatttcgct catgatgttg taggtataca gaaccatata gatagagaaa
    66841 acaaacgtat gggtgatgaa ttcttaccaa gatattcaag tttatgattt ggcgaaagat
    66901 tcaagagtat gtgtcattat tgataggtac tcttgaattg gaaaggagga atgaatttaa
    66961 gacaacaacg attatgatct taaaacaatc gtttatgtaa ttggcaatct tacgaataat
    67021 tttcatgcaa taatgacaat aaaaaatgaa aaggggtaaa atcaaatgaa aaaattttta
    67081 gtaggaattc tattcacaat ggggctagta ttattatcac cttcagtttc agcagaaagc
    67141 tctatttcca tgtatcgtat gtataatccc aatagcggag agcatctata cactagaagc
    67201 gttggagaaa gagacaatct gaaacgttat ggatggcatt acgaaggtgt cgcatggcaa
    67261 gctccaacaa gtggtactcc tgtttatcgt ttgtataatc ggtataacgg tgaacatttt
    67321 tacacagttg atgccggaga aagagataag atttcacaca caggatggac gtacgaaggt
    67381 gttgcgttct attcctacaa cggagcaaat agagttcctg taacacgttt atataacaaa
    67441 tacgtgaatt ggcatcacta cacgttagat caaaatgaaa agaacgtaat tagtaaacaa
    67501 ggttggaaga ttgaaggtac aggctggtat gcaatgccaa acagcgtacc aaatcctaca
    67561 cctgctccaa gcactgaaaa agtgttgaac gttcctgttg tatggcaagg aaatacaatg
    67621 ttatgcgaag gagcttcttt attagaaggt ttacactaca aaggtgtagc cacaaatcaa
    67681 agcttaacca gttttgtaaa ctatatgcca aaagctaatg acaataatcc ttatcatggt
    67741 tactcaggag agtggcgtca taacgttaat ggaacgtatc aaggcatgat ggctgaccca
    67801 gtagttaaat gggcaaaaaa cgttggcggt aatgccgtca atatcactgg ttcaggaacg
    67861 aatggaatca agaatgaaat tcgcaatggt aatccggttg taacttggat tacttataac
    67921 tatgctacgc cagagttcaa acaaatgcct tggggtcgtg cagtatggaa tggacatgta
    67981 gttctcgtgg atggcttcag aaatggtgca taccatgttg ttgaccctgt atttggcgca
    68041 aaatggatca atgcaagcac gtatgagaga gcatttaatg tgactggaat ggcggttgct
    68101 gtacgttaat tgatagaatt atcaactaaa tgaaataaga gcttaattac tgaaatggta
    68161 aataggctct tattttttta gaggaaattt ttgtaatacg aatctataac aaaaaatatt
    68221 gaatgtagta cacaaaagtg gtatattaaa atcgtagaga ttatgcgaag aggtgatttt
    68281 gatgaaccaa agaagaagaa aaaggttaga agaaataagc gagcgacttt ccgagctaaa
    68341 ggatgagtta gaagtaattc aagaagaaga gtacaaagaa aatataccta aaaatctaca
    68401 gggatcagaa agatatgaaa aagcagaaga atccgttgat caacttgaag aagctgttga
    68461 tggtttatcc gacatattag aattgattga agatatagct agctagagat gattaatgaa
    68521 gatttcagga gtgagaataa aatgattgat atttcactga tagagaagtt acttttctca
    68581 aataagtaca ccgcaaaaga gctggctaca agatggcaaa tatccgaatc agctattaaa
    68641 gcctatcgtc aaaataaggg aagcgtagga tggcgtgatt ggaaagggat cagcattgga
    68701 aaagcagaag acataatgaa acgtgaagga cttcgatcct ataccacttc tgaaaaagac
    68761 aaataactta atgtttgaaa agataaaata tctgtcttaa agctatgtca aattcaaatg
    68821 gtgaatgttt gctaaatata atgcaaaaaa aggaagggaa atattaaatg ataagcgaaa
    68881 atttgtctta tgagaataat aaacatctag ttaaagaaaa taagaaagta gaagattata
    68941 agaacatgta tatagaaatg aaaaaatcac cactgtgtat tcaatataaa aatgataatt
    69001 ggaagcaagt agtcgaattt gtaaaacctc atagtatacg aagagtacga agggggaaga
    69061 aaaaaagtga acttgtaaat agcggaagag cggtaattag agttataacc aaagattatc
    69121 cagttgaata tggagattat attttaaggt taagttatca tgcttttgtt gtgttgaaag
    69181 aagagcattt caacgagttt ttcaatttaa aaagtaagta atcatatttt tttgtagacg
    69241 tgtataaagt taactaaatt gcgaggtgat gacatggtag caaaaaagaa tactctaaaa
    69301 gaagcttctg aaaaatatca agatatgaaa agacgaggat taataccgaa agacaaaaaa
    69361 ggtatatgga gagaatttgt taaggaagtc agtagtgatc gaagtggcgg tgactttgtt
    69421 ggacgatata cagcaaaagg ctatagcaaa cgattaagga tcactgttga atatggaacg
    69481 aatgaatcag ctacagagct gaagcaaagg tacttagata cacgaaggga agcttcaaaa
    69541 aaatataatg atttcaagag cagaggtctg attcctaaaa agaaaaaggg aatttggcgt
    69601 gagtttttca aggaagaaga tagcaatcgg aataagggag acttcattgg acgatacaca
    69661 gcaaaaggct acactaagaa tttagggatc aaggttgaat acggaactgg tgaaagttca
    69721 tgggaattga gaaatcgcta tttaaataca ttgttagaga aatataaagc agaattattg
    69781 gagttgttcg atgttaatga ttttatcgag atggctgaaa agtatggtca tgaagaaggt
    69841 tttatgatca atgacattat ggttattgat aattttacgg atttattagc acttgcgaaa
    69901 aaagcaaggg atttaagaga aacgcagatg tatctattca gaaataaaaa cggaagaaac
    69961 cggagaactg aatcgagtga gattgaagat tactacgatg cctttacaca cgatctggga
    70021 gcctttgtag acgagataag tggtgtaatg aacaaatata gggtctagaa taaaaaagcc
    70081 ggagatgagc agataaatgg gaaacaatag catatacaca cctgaaatgc agaataaaat
    70141 taaaagactt gtcggattag ggtggatgac aagaggaaaa ttagattctt ttagtacgat
    70201 caaatatctt ttgatggaca tttaccgtca gaacaagcaa acaggaatac attttttggg
    70261 ctatgataag ccggaagatg cacctttctt tgttccaagt tcagcctata gagccagtac
    70321 ctccggtagc atgtataact tggatttgtt tgaggaagga gcaaagatga tcgaatatga
    70381 tttcaacgaa gcctattcga ggatcatgag aaattatcct ttgccgtcaa acacttattt
    70441 gaaagcaaaa tataatacag atcaagctat tttgagagcg ataaatagac caaaagtaag
    70501 accgtatgaa aatttaagaa cgtatatgtt ctttttggtt aattttgaag gaacagccaa
    70561 agaaggaaca tatgctaatc caaaatcaca gtcgatgttt gcggattatg gcgaaaatcc
    70621 caaaacagct aatgagccta tttggttatc ggagattgag ctaacactta tccttgatta
    70681 ttatgatatt aaagagatgg aagtcctaga tagccacaca tttttgacga aaaaaggatt
    70741 actcaaagaa tattttgaaa gaatcgagcc attaaaaact gatcctgata cgttgaagct
    70801 ttataaaaat cttagaacga aagtatttgg tgctatcgga caaaaatcat taagagaagg
    70861 agaaacaagc accttcgata aatacagtat gtataatcga gcgtattcct ccatggtagc
    70921 aggcgtattt agagatcgta tggttagata tgaacagaaa tacgttcata gcgcatatgg
    70981 gctattaaaa attcgtactg atggattgta tttcagatcc gaagtaccag agtttgaaga
    71041 gctgtataaa cttggagtag ttaagaaaaa agttcataca atatccaaag aagaagtcga
    71101 aaaagcttta gaatttaaaa acaaaggatt tgaaaataag ggctcctttg ggaaatctaa
    71161 agatgaagtt aagggtgttg tgatagacga tgatttcgag tttgattttg actaaatact
    71221 ctttggaaaa gatggtagga ggtaaatatg aagaagaaaa ttgtggaagg aaatgtaggt
    71281 gttattattc taaaagattc aactgactat gctaaatcaa tggcactaaa agacgaaaaa
    71341 gttgcacgca tggataaaga tttagttgaa tttctgatgg atgatacaga aagattaaaa
    71401 ggggatcagt ttttgagttt aatgaaagac aaaggcttaa acacatatgg tttatttgat
    71461 tataagaaat tagctataga gtgggtaaaa gaaggagaaa tattttttat tgaagaatgg
    71521 gaaggtactg agaacttagt tcttcatcag tatcttttga aagcttaatc taagtaaaac
    71581 agttctgact agttatgctt gtcagaattt caaaggaagt tttccataac catcatcatt
    71641 caaaaataaa ggatttgaaa ataagggttc ctttgggaaa tctaaagatg aagttaaggg
    71701 tgttgtgata gacgatgatt tcaagtttga ttttgactag atttttttga aaggtttaag
    71761 agtaaacaag gtaagaacta agatcatgaa gattgagagt aaagaagata gaggacgaat
    71821 gtatgagaac acactatatt tatttagaag ataaaattgt agatgaaatt ccggcaaaaa
    71881 gtcgagaaca agctagaaaa ttatttattg aaaaatacaa agagatcaat ggagatagtg
    71941 aagttccaaa agtggtcgta acagttagaa aaaggcaaac aaaaaagaga agtacgtttc
    72001 atgtcagccc tgatatatat aatcttatag agcgacatag aagtgaagat aatatttcta
    72061 tctctcaata tattgctaca gttattgatg aattgatttc aggaaagtat gactatgctt
    72121 ttgattttga gggtgaaaag gattacaaaa gtgttgctgt ctttcaatct gattttgaga
    72181 agctaaaaaa ctatgctggc aggagaaatg ttaattttgc aagactacta gaagagttct
    72241 actccgaaga gttgggagta ggaaatgaat acaagagaga aacttatgcg aaattgtctc
    72301 ataagttatc ccaagcgctt aaagaagtga cagaagttaa agcggaacta gatgctaaac
    72361 ttgaagaagt gaaaaaatat caaacagaga ggaagaacaa catgaagaat caagtggaat
    72421 ttgacgaaca gaaagaattt gaaaaagcaa gaaaacgcta taacaaaatt atgaatgaac
    72481 ttagctatga acacttaaca gttcatgaat aattgagtga gggtacagaa aaatatacga
    72541 tcgcagatat ggttaatgaa gtggaaactc ttttagcttc tttctttgaa aatggtcacg
    72601 taaacgatga atggcgaaaa gaagaaccta aaagggttaa cgcttatatt gctcgattaa
    72661 aaaggtttat tgataaatat aaggagaata gtgacaaatt ttctaaagat aaataaggag
    72721 agagtgtgat tacatttgcc agaaatcgaa ggaatatttt cgccaaaaat aggtaaaaaa
    72781 cagttagatt tcagcagttt tccgagcgta aatagagatt ataatctagg tgatgaggta
    72841 cagatactaa atattgattt caaagaacta gacttcgctg ttgctgtttc caacaaaccc
    72901 aaggcattgg aacgagtgaa aaaaatatac caagagaatg atcaaaatat caaaaatatg
    72961 atcaaaaagt atagacgaga taattcaaaa gttgaagacg ttttattcaa cggtacggca
    73021 aaacatgatt tgaatgttta tatggcatta ggagtggctt tgtactgtaa ttcaattaat
    73081 cagacagata ttttggttaa tatcgtgagg aatagctatc aaaaaatatt aaaaataagt
    73141 agcgaaacaa acccttatta tgcaatgaaa tatcttgggg ataatttatt aaatgataaa
    73201 aaattgatgc acaacactga agagctgtta tctaatttgg ctgcgattaa ctttctattc
    73261 aaaacaggtt ctgaagatta ttttatagat aacgtactaa aaggtgctta cggaacagca
    73321 ttttatccgc tttacaatat gaaacagcat aaagccgaac aaaaggataa caaacttgaa
    73381 attaaaaaga tgaaagaact attaggtata ggatttgtaa aacccaattc aaaagtcact
    73441 attgcttcgt tagcaactac taacaatgat gggaaaatag taaatgggtt tgacgattca
    73501 gatatagata tattgtcaaa atcatatttt tctttgtatg gagattttgc agatttgatg
    73561 ggtattgata gttacttagt caataatttt gagatcaagg gtagcgagct gaatgatatt
    73621 gtgtatttcg ttttaatctc tctatatgca attgatcaga ataccgagta ccgacaaatt
    73681 gactatttgc tagtttttta tagtttgtta tatcagttcg ttttaactcg gttgtttaaa
    73741 aatgctaagg aagaattgat cctgaattct gattatgaaa tagcaaaaca aattgcaagt
    73801 attagaaaag aaaacaaatc tgaagtaatc aaattaagaa aagaattaag tattgcgagt
    73861 aaagaaaacg gtcggttaga atctttagtc aaatcggcaa aaaaagaaga ggaacttttg
    73921 aagcaagaga ttaaagaatt aaaaggaatc agaaaagaac ttgaacagct gaggtttgaa
    73981 aataaagtat taaagcaatt gcaggagcaa gaacatagac aatcattaaa tggtaaaact
    74041 gaagagcctt cactgtctga aatgatagct tatctaaaac ataaaaacat tcttttagtg
    74101 ggaggacatg taaattttca aaataaatta actgaactat taccaaatat taaaatgttt
    74161 gatgtaagcg aaaataatgg aaagatactt aaaaatttga atacgtgtga tgcgattttt
    74221 ctatatacag attacttgaa tcatggtcta tattatcgtg ttatgagtga aatttctaat
    74281 aaagataaga tattttattt ggataatcat gtgaatatga acttaacaat taaacgtatt
    74341 tacgatcttt tatcacttat ataaagagag aagtgataaa taggacacaa aatttggaaa
    74401 gtaggtaagt cactatgaga gaactaactt tatcttctaa ggaattagaa aagaaaactg
    74461 ctttattaaa cgaaatattt agtgctgatt gtataatcca aagtttaaaa gaaagttcat
    74521 tttcaaaact aacagatcag gaaaaaattt cttatatgct aagtttagat aatctaggaa
    74581 ctaaatatga tgaatcagca agtagcgata agcttttgat tgaattagta tcaagtctta
    74641 gtagttttgg aaaaatgaaa agatttaatg tgatattaga aatttttgct tggttaatcc
    74701 cttcatttat ttggtttttt tatattttca tagttgaatc tgagttaata gccaaggtct
    74761 ctcttggact gttaattccg atataaatag gttcagcaat ttactttaat aacttgtata
    74821 cacctattca aataaaaaag cagttattac atgaaggatt aagtggtaat atgttaaaaa
    74881 gaattgcatg ggataaagat aataaaacag atattgagct taaagaatat aaatacaatt
    74941 atttctcgag atgtatagat agaaagttac tgtttaaaaa agaaggatta gaatttagtt
    75001 ttgatgaaga tgaatttgaa aaattagtga tggactggcg taagaattta ctggatacgg
    75061 tacaattcta aaagcaattg aggtcgaaat tccgatactt gaatcatgat ctatattatc
    75121 gtgttatgag tgaaatttct aataaagata agatatttca tttggacagt catgtgaata
    75181 tgagcttaac aattaaacgt atttatgatc ttttatatgt ttataaacat taatgaggtg
    75241 ctaaaattga caacaataac tatgacaaaa aaaatagaag tatatgttga tggatcacaa
    75301 gaagaaaggg attccttttt tgattttttt tggaaaaata gtagagaata tgtaaaagcg
    75361 ttgaatctgg tatataaaca gctaatgttt gaagagttga taaaagatgc aattaaagaa
    75421 atggatcaag gttatgctga gagagaagaa agtattcaaa atcggattga aaagttagca
    75481 tatactgatc caatagatca aaaaaaactt gataaagcaa aagctgaatt atctaaattg
    75541 agaaatgaaa aaaataaaga agcgagagaa atattaacgc aagcgatagg gttgaagagt
    75601 caaacgagaa cacgagatgt agcaaaaaaa ttagactttg actttggaga ttttgttgat
    75661 tccgcaaata tgaaagctag taaagatttt ggcaatgatt ttatcggaat tgtgaccgga
    75721 caaagaacgc ctagaatata taaaaataga aacaaatatg gattattacc ttttagaggt
    75781 cgagatatta aaatccataa agatgataag ttttatattt atttacctaa aggctttagg
    75841 tttaaagtga atttaggtag caagccaaga aaagcaagag atgttgcttc agttttacaa
    75901 cacattatgg atggcgatta caaattaaat caaagtaatc ttatttttga tggaagaaaa
    75961 ttatttttta atctaacaat ttcttttgaa aaaagctata atgaaatgga attcaagaaa
    76021 ggtaatgaat tgatcgtaaa ctttgcagat ttgtgtagcg gtgaatgttt aattaatgat
    76081 aaatctgtaa tgtcttttgg tgatagccaa tatataagaa acttcaaaag taaaatttta
    76141 gcaatgaaat caaaagaaca aagccgagga gtcttttcta agggcggtca tggtcgaaaa
    76201 agaaaattag atcaagatcg atgggaagca ataaagaaaa gagaaagtaa ttttgttaaa
    76261 acttataata atcaatgttc tgcaaaaatc gttaaaactg ctattcgcaa taaagctcaa
    76321 attattcgta tcattgaacc agataaggct tatggcgaat gggcttacta tcaattgaaa
    76381 gaacaactag taaacaaagg aaaaagatat gggatagaag tcagaagtta gtaaattaaa
    76441 caatcgttga tttggcaacg aaatagtgag ggaaaatcca ctcactgaag ggtaaactcc
    76501 gtcaagttgt gtgaccagac ggaaggacga atgttgttga ggttttagaa ccatataaaa
    76561 cagcatgttt ctcaaatttt taggataagg gaaattgcta gcagtttgtt ttagaaccat
    76621 ataaaacagc atgtttctca aatgagtact ttaaattaat tgatggcgtt cctgctttag
    76681 aaccatataa aacaacatgg atttaaaaca agaagtaagt cagttctcct tttactttag
    76741 taaggaaaaa taaagtattc tcaataaaac ttaaaataag caaacctttg ttttaaaatg
    76801 attgtcaagt taaaaaaatc tgggatcata taaaatagta tagttctcaa atatgattag
    76861 aaaccctatt aaagagcaat attaagccaa cttacttaaa tcgtttaatt aagaacaata
    76921 atctctttta gtcagacttt tagtctgact tttttgtatt tccaaaattt attctttaca
    76981 aaaacgaaca tacgtttgta taattacttg tgaatggggg aataaaaatg tttgattaca
    77041 gtagagaacc ggtgaatgac tattttttaa tcgacatgaa gtctttctat gctagcgtgg
    77101 aatgtattga acgaaattta gacccaatga ctacaccgtt aattgtcatg agtagatcgg
    77161 acaacactgg ttcaggtctg actctagctt cttcacctac tgcaaagaaa aaatatcata
    77221 ttactaatgt tagtagagct actgatttac cttatccatt accaaaagaa cttcatattg
    77281 ttccaccacg aatgaactta tatataaaaa aaatatggaa gttaatcaga tttttagaaa
    77341 gtatgtcgca gatgaagatt tattgattta ttcgattgat gaatcaattt taaaagtgac
    77401 aaaatcctta aatttattta ctatataaat tgagttaaat tgtattcg
//
LOCUS       DAZKKZ010000005        74951 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.005, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000005 DAZKKZ010000000
VERSION     DAZKKZ010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 74951)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 74951)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..74951
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.005"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(323..1105)
                     /locus_tag="ACG8LA_000372"
     CDS             complement(323..1105)
                     /locus_tag="ACG8LA_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202707.1"
                     /translation="MENSSNSAEVNVSTSTSEVVKCSQETTSLPEELLGDWQINNKDA
                     GIEISDSKAVFRIGRSQVESKDYYVDVNNKMLLHVYFSFEYDSVKYIEVSIERTGYSE
                     FISKSVGILTMHTKDGQYISLGVKRVSGENNETEAVTEQTMDERIDSSKSNETEVDTG
                     KTIDERIDSFIETYTAIPPTWKLVNEDKGITINTDTEISTDAQSLSDLLANLTGISNA
                     VTEQVGKDIPLRLLENGKKDYSVVFKNGQVTDYNEVFKKVIE"
     gene            complement(1170..2006)
                     /locus_tag="ACG8LA_000373"
     CDS             complement(1170..2006)
                     /locus_tag="ACG8LA_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HFQ0202708.1"
                     /translation="MRVIKTLNNSLILCLDKQGKEVILMGKGIGFQLKKGDLVPADKI
                     QKVFKLDSLSDALKKDYIKLFEAAPDDLIICVKRIIDYANAKFDFKLNKSLFFTLVDH
                     LKHAIERSQKGIVFQNRLLIEIQKYYPKEFEIGCYAIQLINKKMNVQLPEEEAGNIAF
                     HIVNAQSEQANMEETMLSVRALKDILAMLGYLFPEKKVDKDSMLYLRFVTHLQFFIAR
                     MIKKEELPEKDDFLLASVKQRFPKEYRAALKIKEYVQEEMGASANQDELLYLTLHISR
                     VY"
     gene            complement(2024..3433)
                     /locus_tag="ACG8LA_000374"
     CDS             complement(2024..3433)
                     /locus_tag="ACG8LA_000374"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010757186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFQ0202709.1"
                     /translation="MQYKQLSAFPEKFLWGASISAYQAEGAYQEDGKQPSIIDKYQHT
                     EGVANFEVASDFYHHYKEDIQLFKELGLKAFRFSIAWTRIMDIENNKTNQKGISFYHQ
                     VIDECLNQGIEPIVTMYHFDLPYFLEEQGGWLNRATIDYFVDYVQVLLTEYGDKVNYW
                     LTINEQNTMILHPGAIGLPPSGELPSKKELFQINHHVLLAQARVIHLYHQLNLKGKIG
                     PAINLTAMYQATSSPEDAIAAHNWETLRGWSFLDVAVRGKYNYLFENYLNDRGLYPKI
                     EAEDQAILSSGKPDFIAINYYSTATIAASKNDGSDVSARAGDQQIMLGEEGVYRAAEN
                     PYVDKTPYGWVVDPTGLRLTLRKLYDRYDLPILITENGYGAPDIVEEDRRINDQDRID
                     YLAKHILAIQAALTDGVDVFGYLPWSAIDVVSTHQGFNKRYGFIYVDRTDENLKELKR
                     IKKESFFWYQKVIARNGLA"
     gene            complement(3447..5270)
                     /locus_tag="ACG8LA_000375"
     CDS             complement(3447..5270)
                     /locus_tag="ACG8LA_000375"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HFQ0202710.1"
                     /translation="MDYREVGRNVLQQVGGKENVVSLTHCATRLRFELKDKRKADTKA
                     LEKTLGVISVVDSGGQYQVVIGNEVQTAFKEIQKEVGTSIKKGPSSDNQESIISRLIS
                     VISTTFTPMIPAITGAGMVKAILAVLTLTGVLSDSSQTYIILNTIADAAFYFMPVLLA
                     YGAAIKFDVNPILAITVAGILLHPNISQLFSTGDAVSFLGIPVLAADYAGSVLPIIFT
                     VWIMSYVEPFADRISPSFIKFFTKPMLVFLIMGPLALVVIGPFGTLLNDLIAMGAEWI
                     NGKAAWLIPFLMGGLQPFLVVTGTAWAMTPIATMQLSSTGSEMINGPGMLASNIAQSG
                     ATFAVAAKTKNKELKQLAVSTGITALMGITEPSLYGVTLKLKKPLVASMIGGAIAGLY
                     AGLSGLVRYAFVSPGLAALPAFIGENPMNIVHAIITCVIAFVATFIIAYLIGFDDTSD
                     ESEQTAIAEAVIVENPVKGTVCPISEVNDAVFSKGLLGKGVAIHPEENSIYSPVEGEV
                     ITILESKHAIGLRSKEGIELLIHVGIDTVNLKGEPFEVFVKAGDQVSAGQLLINADFA
                     AIRNAGYDDTVIVVVTNSENYAGISEASGSLKEHEPLMQIS"
     gene            complement(6113..6439)
                     /locus_tag="ACG8LA_000376"
     CDS             complement(6113..6439)
                     /locus_tag="ACG8LA_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202711.1"
                     /translation="MNKVNMNKKFIIIVIVVLAIIGIIFSKMTGTSGLEKSSKPLVTQ
                     ILQEQYNLNRSCDDVTITHENGDNTYRAKAILDNGSAININIEYYPKKDRIYVEIPYA
                     EVLMLN"
     gene            complement(6485..6847)
                     /locus_tag="ACG8LA_000377"
     CDS             complement(6485..6847)
                     /locus_tag="ACG8LA_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010717431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-ribbon domain-containing protein"
                     /protein_id="HFQ0202712.1"
                     /translation="MYCRKCGKEITDESKYCQFCGALQETDETTGADAVKKSTEQTIN
                     EMKEQIVHGQETGKLYLIIGWISMVVALAFIPVVFGAVAVIMGYLYRDKDEQMGTILM
                     IAGVAGAIFGVLLGMSMY"
     gene            complement(6884..7098)
                     /locus_tag="ACG8LA_000378"
                     /pseudo
     CDS             complement(6884..7098)
                     /locus_tag="ACG8LA_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324259.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            7226..7561
                     /locus_tag="ACG8LA_000379"
     CDS             7226..7561
                     /locus_tag="ACG8LA_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFQ0202713.1"
                     /translation="MKQKQYAKVIREKRKALGWTQKELAEKIFSTQQAVARWENSVTE
                     PNLDSLTALSRALGTPVSHFLDNVVVDYEEEFLALYRSLSTEDAVRTIDYMKLLKRQE
                     NERNQLLKD"
     gene            complement(7637..9634)
                     /locus_tag="ACG8LA_000380"
     CDS             complement(7637..9634)
                     /locus_tag="ACG8LA_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202714.1"
                     /translation="METSMINIPIYVDKEKLLEKPVTKKEKTDVRDRCLDNYREVTRD
                     EFVEILNSSQSFIPSKTKNKGNDKESFVETRVIILDVDNTVKDEKGKVVDLSKDDSRY
                     LSIEKVLSINLVHNSAFAIQKSIRYSENLEKYKIVFLLKEAITDYGKMVAVYEYLKKN
                     IPGCDDNVNASNRMFFGGYKSDAVIIINEDNMLDITELPIDFTMTCSKNCQSDSGREY
                     ELVNETDFVKLIKNDDKEEMKQWFKDCLFDSSDMSFNEIYERLLTIDMNKLLKSSKNL
                     RCLFHNDHNPSASIFTSKTGHSIFYCHSSNCDISENFIGVVMLILKKDSRVETFNWLL
                     ENLDLYPTHFRKLKEESKVLFDTLESMKDKLFRTIRNYLEEMRRVYDVLLSDVNFFDD
                     SKESVTCILSGEQLAKKMSFYYGKTYDIDKCNKLLSLMTFIGLIKKLDDEDVPLKMLE
                     YLNRLKEEKALGNFNHKRSNVYRLDVFNATSVIQKLNEDILPLLEKFHFTYQYFSYEW
                     VKICFNEKEAKRVFPQNSRSELSKEKQLILDEAHEVLQGLSWQGTYLMTEKELTNTVC
                     ERLRNVGNNSVENALKENRGYFVKQGFTLERASKDIKRLYNVKASSSFLVYLAKGAGI
                     DEVIKELILSGVELVPLYQFTSVTRDDGRRVRKRKDPIVLN"
     gene            complement(9732..10007)
                     /locus_tag="ACG8LA_000381"
     CDS             complement(9732..10007)
                     /locus_tag="ACG8LA_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0202715.1"
                     /translation="MSLQIIDSIVSIQVEQQVKEIITVLKPMLEDIISGVTLEYMDYQ
                     QASEYLGVSVGTIRKYVSQYGLPVIKIDTVIRFKKSDIDSFMERYKG"
     gene            10239..10973
                     /locus_tag="ACG8LA_000382"
     CDS             10239..10973
                     /locus_tag="ACG8LA_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFQ0202716.1"
                     /translation="MIKRPPINYLERKKILGTKIKAIRKSKKLTQPAFGLMINNGQLI
                     DKKTIYEWEKGTYLPIPERLSRIADLGNMSIEELVCGNVEEYILGIILYRDSIVLDGI
                     TFPDKNLFQHLRQQFPPVHSNLDTWLDRYSKLEPEMQEFIANKTCNKVKNEKISLFNI
                     LKIEELFINAIVEEFDNNILFLTSSIEELLERMVDEWLPIQLKDMSYPEEAVREITDN
                     INKLEQTISSIGKKYTKKKMKGGDTI"
     gene            11012..12154
                     /locus_tag="ACG8LA_000383"
     CDS             11012..12154
                     /locus_tag="ACG8LA_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFQ0202717.1"
                     /translation="MAKISKYKKKNGQVAWMYKGHIATDPRTGEKINTTRRGFSSKQE
                     AQKDYDEYRHQILYGVKKKAPDMTFEDLYNEWITHQRTSVKASTIAISVRYANNQILP
                     AFGKLKLSNISVPYCQKVVDEWHSKYESYDYMRKQTAQILRYGVAMQYIDNNPMEKTL
                     LPRKKEYEKNRKFYSKEELNNLLDAFKDFGNMKQYAFFRLLAYTGMRKSEVLALQWKD
                     IDTFNKELHVNKTLAVDEFGKVIIQSPKTRASRRVISLDTETLSILNNWKLQQKEEYL
                     KLGYNTSSKEQHVFTTVKNTLYIPNTVNDWLRYILKKYNLPRITPHGFRHTHASLLLE
                     AGESVKVVQQRLGHENSKVTLDIYAHITNNAPKKTGQDFADMMAHQ"
     gene            complement(12249..13640)
                     /gene="sufB"
                     /locus_tag="ACG8LA_000384"
     CDS             complement(12249..13640)
                     /gene="sufB"
                     /locus_tag="ACG8LA_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HFQ0202718.1"
                     /translation="MGVPELEEYKFGFHDDVEPVFSTGEGLTEEVIREMSRIKGEPEW
                     MLEFRLKSLETFNKMPMQTWGPDLSDIDFDAIKYYQKPSDKPARDWEDVPEKIKDTFE
                     KIGIPEAERAYLAGASAQYESEVVYHNMKDEFEKLGIVFTDTDSALKEYPELFKEYFS
                     KLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDVPLQTYFRINAENTGQFERTLIIVD
                     EGASIHYVEGCTAPTYSSNSLHAAIVEIFTRKDAYCRYTTIQNWSDNVYNLVTKRAKA
                     YEGATVEWIDGNLGAKTTMKYPSVYLDGKGARGTMLSIAFAGANQIQDTGAKMIHNAP
                     NTSSSIVSKSISKDGGEVNYRGQVTFAKNSAGSISHIECDTIIMDEWSKSDTIPFNEI
                     HNSQVSLEHEAKVSKISEEQLYYLMSRGLTESEATEMIVMGFVEPFTKELPMEYAVEL
                     NRLISYEMEGSVG"
     gene            complement(13645..14115)
                     /gene="sufU"
                     /locus_tag="ACG8LA_000385"
     CDS             complement(13645..14115)
                     /gene="sufU"
                     /locus_tag="ACG8LA_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly sulfur transfer protein
                     SufU"
                     /protein_id="HFQ0202719.1"
                     /translation="MGLSKLDNLYRQVILDHSSHPHHRGSLTDSTSKIELNNPTCGDV
                     IELQVDVKDGIIKNIAFDGSGCSISTASASMMTDAVIGKSIEEAEHLTVDFLQLVQGK
                     EVKDPDQLGDAAMLGGVAKFPARIKCATLAWKALGKAMENDGTAAFHHYHKEEE"
     gene            complement(14102..15337)
                     /locus_tag="ACG8LA_000386"
     CDS             complement(14102..15337)
                     /locus_tag="ACG8LA_000386"
                     /EC_number="2.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0031071 - cysteine desulfurase activity
                     [Evidence IEA];
                     GO_process: GO:0006534 - cysteine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HFQ0202720.1"
                     /translation="MIDAKKLRNDFPILFQDVNDEPLVYLDNAATTQKPKQVLQALAY
                     YYEHDNANVHRGVHTLAERATHDYEQAREKVRAFIHAKETAEVLFTRGTTTSLNWVAR
                     TFGDRYIKAGDEIVLSYMEHHSNVIPWQQLAKRTGAVLKYIELTEEGFLDMEDAAKKI
                     TDKTKIVSIAHVSNVLGVFNPVQELAELVHENGGVIVVDGAQSAPHMAIDVQALDCDF
                     FAFSGHKMCGPTGIGVLYGKRKWLEEMEPVEFGGEMIDFVELYDSTWKELPWKFEAGT
                     PNIAGAIALGHAIDYLQKLGMDNIHRYEEELAAYVLPKLQAIDGLTVYGPQDPNFRTG
                     VVAFNLDGLHPHDVATALDMEGVAVRAGHHCAQPLLKYLEVSATARASFYFYNTTQDA
                     DRLVEAIMATKEFFQHGTI"
     gene            complement(15334..16620)
                     /gene="sufD"
                     /locus_tag="ACG8LA_000387"
     CDS             complement(15334..16620)
                     /gene="sufD"
                     /locus_tag="ACG8LA_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HFQ0202721.1"
                     /translation="MKEKNWLDYLDAVNDFSLSKGEPDWMRTFRQDALAKADELPLPH
                     IDRVKFHRWSLFDVKETQTISETGTIPAFDAMKDNPVLVQQGSWTIFEQLPVELAEKG
                     VIFTDLFTAMIEYPELVQEYYMKKAVNMNEDQLTALHVAFMNSGIFLYVPKNVVIDEP
                     LESLFIQDGASDEHFFKHVLIVADEHSEFSYLERFQTTKEQVAKSSGNIIVEVIAKAG
                     SKIKYSAVDQLGENITSYMNRRGHILRDASVDWAIGVMNDGHVIADFDSDLAGEGAHA
                     EVKIVAISSGRQIQGIDTRVTNKAPHTIGHILQHGVIREKGTLTFNGIGHILKGAKGA
                     DAQQESRVLMLSDKARGDANPILLIDENEVTAGHAASVGRVDPEEMYYLMSRGLHKEE
                     AERLVIRGFLGSVLTAIPVEQVRKELVEVIEGKLNG"
     gene            complement(16633..17406)
                     /gene="sufC"
                     /locus_tag="ACG8LA_000388"
     CDS             complement(16633..17406)
                     /gene="sufC"
                     /locus_tag="ACG8LA_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HFQ0202722.1"
                     /translation="MSVLEIKNLHVSIEEKEILKGVNLTMKTGEIHAIMGPNGTGKST
                     LSAAIMGNPNYEVTEGEILFDGKNVLDLEVDERARLGLFLAMQYPSEIPGITNAEFMR
                     AAINAKRDENDKISVMAFLKKLDEKMALLNMPEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFAILDEIDSGLDIDALKVVAKGVNEMRGDNFGALIITHYQRLLNYITPDVVHI
                     MMEGRVVMTGNADLAKRLEAEGYAGISKELGIDYKEEEA"
     gene            complement(17603..18451)
                     /locus_tag="ACG8LA_000389"
     CDS             complement(17603..18451)
                     /locus_tag="ACG8LA_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HFQ0202723.1"
                     /translation="MKKKIFGFAAALLLTVGLAACGNNSDSKDSANKADDTTLKVGAS
                     PTPHAEILEHVKPLLKDEGIDLEIVKFDDYVLPNQSLEEGDIDANYFQHIPYLNKEIK
                     EKGYDFVNAGAVHIEPMGLYSKKVKDVSELKDGATIITSNSESDWGRIITILQDAGLV
                     KVKDGVDLETATFDDIEENPKNLKFNHTIDPSLLASTYQNDEGDLVAINANFAYGAGL
                     NPLEDAVLLEKDNSPYVNIIATRKGDEDSDKIKKLIEVLHRKEVQEWITDKWGGSVKP
                     VKADAK"
     gene            complement(18475..19161)
                     /locus_tag="ACG8LA_000390"
     CDS             complement(18475..19161)
                     /locus_tag="ACG8LA_000390"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter permease"
                     /protein_id="HFQ0202724.1"
                     /translation="MDKSFSETYLDFKQINPETMNQAILDTLYMTLISMVLVTIIGLV
                     LGLILYSIGRKNKPYARIIYGIVSIISNIFRSTPFMILMVLIIPFTKAIVGTMLGAQA
                     AIPALVLSAAPFYARLVEIAFREVSPGVLEAADAMGASYWEIIWKVLIPESIPALISG
                     LTVTTISMIGFTAMAGAIGAGGLGGLAWQEGYQRGNLTVTFVATLIILLIVFIVQGIG
                     DFLTKKTDKR"
     gene            complement(19154..20188)
                     /locus_tag="ACG8LA_000391"
     CDS             complement(19154..20188)
                     /locus_tag="ACG8LA_000391"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HFQ0202725.1"
                     /translation="MSLIQLTNVKKTFNGKNGNIQAVNDVSLNVEKGDIYGIVGYSGA
                     GKSTLVRLLNGLELPTSGEVIVNDQDITKLKNKELRTFRKKIGMIFQHFNLLWSRTVL
                     ENIQLPLELAGVPKSKRKERAEELLRLVGLEGRGQAYPSQLSGGQKQRVGIARALAND
                     PEILLCDEATSALDPQTTEEVLDLLLAINKKLNLTIVLITHEMNVIRKICNKVAVMEL
                     GKVVEEGDVLTVFRQPKKEVTKRFVQQDIEPEADSTELLAELIKENPSGRLATLTFSE
                     RNANEPVISQAIRRYNIDVNVVYGKIKQVKEGSFGSLTVLMTGETKELDQAEVFIKEQ
                     GVGIEVIHRG"
     misc_binding    complement(20251..20507)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(20583..20921)
                     /locus_tag="ACG8LA_000392"
     CDS             complement(20583..20921)
                     /locus_tag="ACG8LA_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein H"
                     /protein_id="HFQ0202726.1"
                     /translation="MAGKHLKKKDNLWILFNGKEYCVGLTNEAQEELGDITFANLPKA
                     GQSLKKDEPLIEVEAEKAVNEFASPLTGTVSSVNDKIGEDINILNDSDEMNAWILSFK
                     DVDPKEFDEL"
     gene            complement(20923..21279)
                     /locus_tag="ACG8LA_000393"
     CDS             complement(20923..21279)
                     /locus_tag="ACG8LA_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HFQ0202727.1"
                     /translation="MYTFYWYPKCSTCKKAKAWLDQHGVSYQTVDMIKEVPKASTIET
                     WLETSQVPIRRLFNTSGMKYRELGLKDQVGEFTASKASQVLSTDGMLIKRPLILREDQ
                     LVAIGFNEKIYEGELI"
     gene            complement(21285..22472)
                     /locus_tag="ACG8LA_000394"
     CDS             complement(21285..22472)
                     /locus_tag="ACG8LA_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HFQ0202728.1"
                     /translation="MEKKLKASNDNRIDYGVILPVFLLCLIGLLSLYVALSHDPNNPA
                     VLKGVGMQVVWYLVGAAAIVVIMHLNSKWIWKLTPYLYGLGLVVMGLLLKFYDQNLAA
                     STGSKNWFRFGAFTFQPAELMKIAYILMMALIVTKHNTQVKERTMKSDFWLIGKLLIV
                     TIPVLALIMAQDDFGTMLVFLAIFGGIFLMSGISWRIIAPVVILAVVVGAGTIFLVTT
                     EGGRDLLYKVGFKSYQFARIDSWLDPFHDTSGMSYQPAQGLLAIGTGGLFGKGFNVSN
                     IYVPVRESDMIFTVIGENFGFIGGAFVIFLYFILIYRMIRVCFDTNNEFYAYIASGLI
                     MMLLFHVFENIGANIGLLPLTGIPLPFISQGGSSILGNMIGIGLILSMRYQNEAPARS
                     SRR"
     gene            complement(22663..23508)
                     /locus_tag="ACG8LA_000395"
     CDS             complement(22663..23508)
                     /locus_tag="ACG8LA_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFQ0202729.1"
                     /translation="MFKLLTTFRAVYETRNFSRAAEVLFLSQPAVSNQIKQLERELNI
                     DLFQRNGRKEMLPTKQADLLYERTLVLLEEWEETQQKLLNEQNEEEVCRIVASHTFAV
                     YLLPQLMKHLIKRFPKVHFEIEITNSHESLEQVAKHESDFGFIEKPLETSGVQRYSLM
                     EDQLVIAGDPKSKLWLVREANSGVFHYTQRYFEEMNIQDKKMIVKSNDVIVALLKEGI
                     GRSILSKRSVPENVPMTPLNFHRYFYFIQRTNLVSDQLLEIAEEILRYNESTETSHSE
                     ENLSW"
     gene            23742..24707
                     /locus_tag="ACG8LA_000396"
     CDS             23742..24707
                     /locus_tag="ACG8LA_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HFQ0202730.1"
                     /translation="MKNFLKIIPIPICGLILGLASLGNLFKDYHHVALGNLTGGISMI
                     LMIFIFVKLFILFEHTKQTLHDPIIASVSPTFTMSLMVICTYFVSYESIAPIVKFIWL
                     CAVIFQVILVFYFNYHHVIKADLSIEAIYPSWFIIYVGFGVITVTAGNFFPLIGKIFF
                     WISLICYAFLLPIIIKRVFFVRNMAHPTRPLITIVAAPGSLCLTGYLKNFAEPNFYLV
                     VALFALSQVLYFVVLSMLPRLFKLRFYPSYAAFTFPLVISATAIFTTVHYFNSLGIYS
                     SVLDFLKVAECLFASVVVFYVLAHYVRFLIKEHSKHGKFVSKKIA"
     gene            25084..26127
                     /locus_tag="ACG8LA_000397"
     CDS             25084..26127
                     /locus_tag="ACG8LA_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative sulfate exporter family transporter"
                     /protein_id="HFQ0202731.1"
                     /translation="MKSLSHPIKSVKDSAVREILPGLLLSFAIAAFSRLLAIYLPQLG
                     GATIAILLGILLGNTFFKQPVLAIGTKFAESKLLEFSVFLLGATVTAQTIAQIGVKGI
                     VFVLLQMSVTIIGAYLIGKKLQFSDTSSLMMAGGNAVCGSSAIASIAPSIHAKEEEKG
                     QIITLVNLLGTVMMLTLPFLGLQLFGGNLIEKSALLGGTLQSVGQVVAGASLLDNSVV
                     EFAMLFKILRIMMLVVVVYLFEKFMHKKQPALFETPTDTQKKRKLPLPWYVLGFVIFC
                     LVNSLFSLPVVIDQSAHFISSWFEITALAAIGLRLDFAKFMKEGTRFLSYGLAVGLLQ
                     TVMALLFIWLIKV"
     gene            complement(26189..26653)
                     /locus_tag="ACG8LA_000398"
     CDS             complement(26189..26653)
                     /locus_tag="ACG8LA_000398"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003908 -
                     methylated-DNA-[protein]-cysteine S-methyltransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HFQ0202732.1"
                     /translation="MKIHTPIGFLWLDADESGLTAVSFQPISESESANQRILTRTQEQ
                     FEEYFAGKRKEFDVPLSIKRGTPFQQNVWKALSTIPYGEIRTYKEVAVAVDSPKAVRA
                     IGQANRTNPLPIVIPCHRVIGQNGKLTGYMGNAIDGVEIKRQLLLLEGYLQN"
     gene            26899..27846
                     /locus_tag="ACG8LA_000399"
     CDS             26899..27846
                     /locus_tag="ACG8LA_000399"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFQ0202733.1"
                     /translation="MKVSIVVPCFNEEKTVPLFFDEVEKFKGAHEFEYLFIDDGSKDG
                     TLAAIKKLASAYPYVRFVSFSRNFGKEAALYAGLQASTGDLVTVMDVDLQDPPELLPE
                     MINRITTSDIDCVGTRRSTREGEPAIRSFFAKKFYQLINKISDTEMVDGARDFRLMTR
                     QMVDAVLELTEYNRFSKGLFSWVGFKTEYISYENRERVAGETSWSFWKLFNYSIDGIV
                     NFSDAPLTIASFIGALSCVGSGIAILFIILRALLFGDPTSGWPSMVSIFLFIGGIQLL
                     CLGIIGKYIGKIFLETKQRPVYIIRETEKVKPNELKPHQ"
     gene            complement(28057..30129)
                     /locus_tag="ACG8LA_000400"
     CDS             complement(28057..30129)
                     /locus_tag="ACG8LA_000400"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_function: GO:0098847 - sequence-specific single
                     stranded DNA binding [Evidence IEA];
                     GO_process: GO:0006261 - DNA-templated DNA replication
                     [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0051304 - chromosome separation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HFQ0202734.1"
                     /translation="MKQLILAEKPSVAKDLSKVLGANQKHKNYYEGPKVIVTWALGHL
                     LGLKMPEDLNKEWQSWQMDTLPMIPKKLGIKPLPKTGHQLKAIKQLAQRKDVSEAVIA
                     TDAGREGELVARWILEYVHFNKPVKRLWISSQTDKAIKTGFKQLRPAKEYDALYESAL
                     ARAKADWLVGLNVTRALTVKYADNLSAGRVQTPTLALVRDQEKKIEQFRPQTYFTITL
                     QAGKEQAKMLQKNQFALKTQEEAQKLVQLISTSKGTVTEVQEKLKTESAPLPYDLTEI
                     QREANQRYGYSAKKTLSLVQSLYETHKIVTYPRTDSKYLTNDMKSTMKERLQAVSDFA
                     PEVKQYLKNGAIVQQTKVFQDSKVTDHHALLPTENRARYEKLSNEERKIYQMIVSRFL
                     GLFAQPHKVSQTKVTVEFGKERFIFRQNRVVQAGWKGETETETETVKWEKGMRINPDF
                     AIKKELSAPPKPLSEASLLGQMEKYSLGTPATRAEIIEKLIKSELMERTPQGLQVSPK
                     GKQLLVLVNPSLVTPDLTESWEKDLEAIAAGKKQAGTFLNGIEKETKRLVNEIKSSKQ
                     EYQDFSITQKKCPECGANLREKNTRDGKIYVCTNSDCNYRRRKDPKVSNHRCPQCHRK
                     MEIIEGKNGAYFRCKYDGTTEKLLDKKEQKKKMTKHEERRLLKKYAQAEEPEESPLAA
                     ALKAAMKK"
     gene            complement(30062..30439)
                     /locus_tag="ACG8LA_000401"
     CDS             complement(30062..30439)
                     /locus_tag="ACG8LA_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HFQ0202735.1"
                     /translation="MYQVITMFGDNEPWWFFEDWEEDIEEEETFESFEEARQAYEKQW
                     NEIHQNYEYINAKSNFLSAFWNDGDERWCEECDDDLQQYKGLALLKNHQPITVESRKE
                     FYETTNSSGKTKRCERPKQGAWC"
     gene            complement(30568..31128)
                     /locus_tag="ACG8LA_000402"
     CDS             complement(30568..31128)
                     /locus_tag="ACG8LA_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFQ0202736.1"
                     /translation="MKKRNLSQEKIIDCFRELAEEMDVQQITFQHLAKRLDIKAPSLY
                     NHFKNIRDVKTALTAKLLQELNDQLRRALVGKSGQEALQIYAETYRSFAFSNQAVYEL
                     LISVPHTNEAVLLDGIHETNQIILQIFEAFQLTKEEKVHRSRELRSMIHGYLSLRFLG
                     YFTKEPTIDPEDSYFWMINNFIATLP"
     gene            31278..32570
                     /locus_tag="ACG8LA_000403"
     CDS             31278..32570
                     /locus_tag="ACG8LA_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HFQ0202737.1"
                     /translation="MAARIKEKLFRKRETWEQNLFVLWFGTFMAGIGFSLVMPFMSLY
                     IDTLGNYSTSQLNFWSGLTFSSTFLVTTLISPWWGKLADQKGRKLMLLRASLGMAIVI
                     SLMGCVTSVYQLVALRLLQGIFSGYISNATALVATGTPKEKSGQVLGTLATGSVTGTL
                     LGPLLGGISASAFGYRPTFFITGIILFFVFLLSLFFVHEKFVPVKKENMVSAKQIFKD
                     LKYPHVVIGMFVTTMIIQASNNSISPIISLYIRQLLHGHGNVTLISGIIASIPGIATL
                     IAAPRFGRLGDKIGSERILAIGLGFAILVYIPMAFVTNVWQLAALRFLIGISDACLLP
                     AVQALITKYSPHQAAGRIFSYNQSFQATGNVVGPMIGSSVSSAFGYRGVFLSTSLLVL
                     VNFLLVRHNTQEIHQQETAEEKASGVSIASGHSPSHRQ"
     gene            complement(32630..33748)
                     /locus_tag="ACG8LA_000404"
     CDS             complement(32630..33748)
                     /locus_tag="ACG8LA_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase"
                     /protein_id="HFQ0202738.1"
                     /translation="MKIANFGVEEWLNKWEKKAVYDIAQSSIEALTLDELVGLDGTSV
                     SKFFEKRKNEPLDYGWIEGSDVFKQEVASLYQTVDPENILQTNGATGANLLALYALVE
                     AGDHVVSMLPTYQQLYDIPKSLGAAVDFVHLKEEEDWQFDLEQLEALVKPETKIICLN
                     SANNPTGTLLDRKTLEKIAEIARTVDAYVLIDEVYAPLTDKGEFLSIVDVYEKGIATN
                     SLSKTYSIPGIRIGWTATGPELAEVFRKYRDYTMICGGVLSDDLAVHALKNKEKILAR
                     NKKIITENLVILKQWVANEPKVELVAPNYVSTSFIKLAIEEDDQTFCINLLEETGVLL
                     VPGSAFDLPKHARLGYCCKKETLEKGLFLLSEFLKKQA"
     gene            complement(33762..35183)
                     /gene="arcD"
                     /locus_tag="ACG8LA_000405"
     CDS             complement(33762..35183)
                     /gene="arcD"
                     /locus_tag="ACG8LA_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0043858 - arginine:ornithine antiporter
                     activity [Evidence IEA];
                     GO_process: GO:0006527 - arginine catabolic process
                     [Evidence IEA];
                     GO_process: GO:1903826 - L-arginine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine-ornithine antiporter"
                     /protein_id="HFQ0202739.1"
                     /translation="MEKKSTGISKWGLVALVVSSSIGSGVFGITSDLASSAAPGPAIL
                     SWIIVGIGILALVLSLNHLGEKRPDLDGGIFGYAEASFGKLGGFISGWGYWLSAWLGN
                     VAFATMLMSAMGEFFPIFKGGQNVPSILFASIFIWGLTLLVNNGVEGASVINTIVTIC
                     KLVPLFLFLIFVFIAFKVNIFTADFWGNVSDNLVNGTGQQGTIWLQIKGCLMVMMWVF
                     VGIEGASVLANRAKKRSEAQQASIIGLLCLLFIYILASILPYGVLSQEELATISQPAM
                     ANILKGIVGNWGAALINIGLIISIIGSWLSWTMLPAETTMLMARDGLLPKGWGKTNKK
                     NAPTYSLVVTAILTNLFLLTFLVTDYAYQFAYSLCTAAILICYLLVGIYQVQFSLKEG
                     IKKQVVIGGIAVVFELMGIILAGFSYVLLCSIAYLPGFCFYWIACRETKHQITGKEKV
                     MIGLICVAALLSIGLLAVGWIKI"
     gene            complement(35429..36550)
                     /gene="mnmA"
                     /locus_tag="ACG8LA_000406"
     CDS             complement(35429..36550)
                     /gene="mnmA"
                     /locus_tag="ACG8LA_000406"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0016783 - sulfurtransferase activity
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HFQ0202740.1"
                     /translation="MTDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVAKVAAQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMDLGADYVATGHYAQVTRDENGVVHMLRGVDNNKDQTYFLSQLS
                     QEQLSKTMFPLGGMEKSEVRAIAERAGLATAKKKDSTGICFIGEKNFKQFLSNYLPAK
                     KGNMVTLDGEVKGQHAGLMYYTIGQRQGLGIGGGGDSQEPWFVVGKDLATNTLYVGQG
                     FHHPALYATSLDASEIHFTTNEPMPKEFKCTAKFRYRQQDVPVTVRLLDDNRAEVVFD
                     EPVRAITPGQAVVFYDGMECLGGGLIDHAYQETKVLQYV"
     gene            36954..37553
                     /locus_tag="ACG8LA_000407"
     CDS             36954..37553
                     /locus_tag="ACG8LA_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HFQ0202741.1"
                     /translation="MNYFISDMHFFHERLLGKNDFAPRLFANVDEMNQQLITSWNAVI
                     KETDHVYHLGDLAMHPQYEKANAEILELVTQLQGTIHLIKGNHDSRAFFRYLEKNDPR
                     LTDGSPKFYFYDVGAIVKFDHQQYYLTHYPMLLGPNDTIRNLHGHIHHYSVPIENDVN
                     VGVDAPERELLKEKLPFGTPLSEQQIKEIYEAKRKYDRS"
     gene            complement(37691..38977)
                     /gene="efmA"
                     /locus_tag="ACG8LA_000408"
     CDS             complement(37691..38977)
                     /gene="efmA"
                     /locus_tag="ACG8LA_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter EfmA"
                     /protein_id="HFQ0202742.1"
                     /translation="MENEQSVVLTNWKRNYLFFLSGQFLSGITSMVVQYAIIWYLTRE
                     TGSATILSFATLLGMIPMVLLSPFVGPLVDRWDKKALLIVTDIIVAIFALILAVVGTI
                     SESFPIWLVFVSLFMRSVAQTFQMPTIQSIMPTIVPSSHITRTNGQLGMVQSANFIIA
                     PALGAALFSVVPVNYLILLDVLGAVFGVGLLIFVKIPKVSPEILEVPLTIFKDAKFGL
                     QQLMDNKGLWYITINGAFVMLLFMPAISLYPLMTLDYFGGSVGQAGAVEVVYAVGMLL
                     GGALISFIGTWKDRMKPIIIAYIIMGLTIGASGLVPNDSQGFLYFLILNAGAGCATPY
                     FNTLLMAMIQQSYESNVLGRVLGNFNSLMNLAGPIGLLFAGPLADRLGVEKMFLFSGI
                     GILLCGIVLFLTSAARNYDKELQKKLVKEHHEQKDE"
     gene            complement(39248..39592)
                     /locus_tag="ACG8LA_000409"
     CDS             complement(39248..39592)
                     /locus_tag="ACG8LA_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HFQ0202743.1"
                     /translation="MAFETTATVLGAPISYRLHPDAKRYTLRDNGFTETNGGNYQLIR
                     PLDATPQSKEGFKLKITVSKDIQTLKMSITTANGLKAVNIFKDPKQKMSQDKFYFLMD
                     GMISRGLFEKVE"
     gene            complement(39729..40874)
                     /locus_tag="ACG8LA_000410"
     CDS             complement(39729..40874)
                     /locus_tag="ACG8LA_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase family protein"
                     /protein_id="HFQ0202744.1"
                     /translation="MNEVKTIYLDHAATTPMHPQVIEAMTAIMQDTFGNPSSIHGFGR
                     HAHEKLETARQIIADSLQAKPHEIIFNSGGTEGDNTAILETAFSRQKEGRHLITTAIE
                     HPAVLNTMKYLETKGFDVTYLPVDEKGNLSIEEVKKALREDTILVSVMYGNNEIGNLM
                     PIKEIGELLADHPAYFHTDAVQAYGNQTIHPEELGIDLLSISAHKINGPKGVGFLYKR
                     DGVNIPALLLGGEQEEKRRAGTENLAGIWGMAKAVELLSPEEREARNNKYKGFQQLIL
                     DTLEANEIPYQVNGDLTNKLPHVLNLRLIGEANDLLLMKLDLNGVAISTGSACTAGNI
                     EPSHVLEAMYGEDTPILKESIRISFGLGNTEDDIQYFLDQLVRAVKK"
     gene            complement(41054..42028)
                     /locus_tag="ACG8LA_000411"
     CDS             complement(41054..42028)
                     /locus_tag="ACG8LA_000411"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HFQ0202745.1"
                     /translation="MSNKYQDDTLKIFSLNGNRPLAEKIAKVFGTELGKSVVKQFSDG
                     EISINIEESIRGDHVYIVQSTNAPVNDYYMELLIMIDAMKRASAKTINVVLPYYGYAR
                     QDRTAKPHEPITAKLIANLIEEAGATRVLTLDLHTVQVQGFFDIPVDNLFTMPLFAHY
                     YRQLGLTGDDIVVVSPKNSGVQRARSLSEYLNSTLAIVDHADDASTEGGYVIGDVQGK
                     TCIMVDDILNTGATLARAANVLKENGAKEVYACASHGLLSDHAKSILDNAPIKDICIT
                     DSVFTEENRHPENLTIVTCSELMGEAVKRIHENTPMSPLFRLEEKEFE"
     gene            complement(42108..42983)
                     /locus_tag="ACG8LA_000412"
     CDS             complement(42108..42983)
                     /locus_tag="ACG8LA_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide dehydrogenase"
                     /protein_id="HFQ0202746.1"
                     /translation="MKKRRRSQLNQVVDKPLYFKVDKKIKKLASTQQLQSRKSKLLFL
                     ALVFEDQSYVIIDQSGHPVEYSPAKYTYQEGLSCKKWKLINEEPIELSRWINRKEDIP
                     VLIEEKRSGKELANCWVGLPEERFLRYKKWATPSGYLCGTYAAAVLLAYYQDYRKGWM
                     LPNEIRKKNTADSLVLTKALRSQIQPLGLPTIPFQVSTGISSFLKKNGNHERARATLL
                     GSWQRATKRIREGKPVMIGILKVLGSTYGNHWVTAYAYFETETGERYYKVHDNWGDYH
                     KVIPASWSNGTVSLP"
     gene            43113..45020
                     /locus_tag="ACG8LA_000413"
     CDS             43113..45020
                     /locus_tag="ACG8LA_000413"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M13-type metalloendopeptidase"
                     /protein_id="HFQ0202747.1"
                     /translation="MNKERLKQDFYEAVNEEWQKTAKIPADKPATGGFQDLVDGIDQL
                     LMGETDDLLAHPEKVSSEKMKHFLAYYQLANDYDRRNELHAQPLQPIIEKVESLQSFD
                     ELNKQFPEWLLDTLPLPFNLDVDADMKNAQTNAFFAYPPSLFLPDKTYYASDHPNGAQ
                     LIGVFFDMAVQLLELAGKEKSQAEAITEQAVQFDKLIAPHVKSAEENADYSKMYNPQS
                     FDTFIKYTDKLDLKKLVTGLIGTTPDKVIVTDPVYFDHLNDILTEAHFPLFKSWMIIK
                     TVRSLSGYLSEEFRQVSGIYSRVLSGTDEAMPQKKAAYYLASGQFDQVVGDYYGKKYF
                     GEAAKKDVEQMVKKMIAVYKKRLEENDWLGDATKEKAVIKLNNLGIQVGYPDKIPALF
                     DQFKTVPADQGGTLLSNTLVFSKLTLKDRFSKWNKPVDRSEWEMSADTVNAYYHPFRN
                     VIVFPAAILQAPFYSLEQSSSANYGGIGAVIAHEISHAFDNNGALFDEYGNLNNWWTE
                     EDLTQFQNKAQAMIEEFDGLPFADGKVNGKLTVSENIADAGGLSCALEAAKTESDLSI
                     EEFFVNWATIWRTKAKKEYQQLLLQIDVHAPAKLRANVQPKNLDEFYETFGITEQDAM
                     YLAPEKRVRIW"
     gene            complement(45561..48839)
                     /locus_tag="ACG8LA_000414"
     CDS             complement(45561..48839)
                     /locus_tag="ACG8LA_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="right-handed parallel beta-helix
                     repeat-containing protein"
                     /protein_id="HFQ0202748.1"
                     /translation="MLKKRIKYSALMMNLLMLSTPVLISVVEVAANEQQSVNEENAHV
                     NIEGMSTMEEIPRTSEDMDTEEGNDPMMKESENEKTKKQSEEANEEWKGVVFGESTSA
                     SRYAIEPLEDGVRLSSTNNGGKFQSSGSDGMTYYYQAIPKDINFRMRATIEIESWTYT
                     NAQEGFALMVRDAVPKNHLFGQAFYSNSFAILGSRIEYVWDSDRQEVVNTSGSKYTMR
                     LGLGTRAITGISSEDPQAAPAPGSVSVETTPLETSAGFLEKETGSYNIFGNGHGNLFP
                     ATNSITKLDVEMKKTNTGLEAYYYDPETGEEMASDIMYDWEKLYASDESVIYAGFAAA
                     RNMTIKVEGIEVAYSDPATDPPGQERPTRLIDPIYTVTSSNHSGNQDHTMSFRANADG
                     LLTIKNKATGEVLKNAKNLAITANREFDYQTKLMEGTNEFTFSFTPDKNYPPEEYVEM
                     TSYETKEILHTVDYRKPKYSTVYVTPEGSDAGNGSRQNPLSLTQALRYAYAGQTIVMA
                     PGTYSFERGLTIPKGVNGTRENPIQLIAEKNPENKRPVLDFKGTGNGMTLFSHYWGLR
                     GFDITNSAAMQKGLQISGNHNLIEEIHAYRNGNTGIQISGSSNDPFEAWPAHNLVKNC
                     TSFENADPGFEDADGFAAKLTIGEGNVFDGCIAYHNADDGWDLFAKNETGSIGKVIIK
                     NSVAYRNGWVPGIEGEGNGNGFKMGGSSLTGPHELINSLSFENLAKGIDSNSGTDIIV
                     NSSTSFNNGSYNVALYTSSAGNTDYHASGILSFRTENLEMREQIRPLNQNEDQIYHSL
                     NYYWNEREKQSENTLGHTISKDWIESLNTCSKEGQQPVTRYENGSIHVHGLMQIKPGN
                     RQTEKERVDGLPLSVGAIFDGETSPSSEYPEYAIVQEPNQTKPNEQNNPIIIQEANGV
                     AENAEGNIIELKPFTVFVSTFTPNQGTPVFEDMRYFPEKIQIVETQSSAQFSNHTAIF
                     SAPSKGEYTLEVTYRSEIFDGEKWSAHTESVTQQKAITVRETADVPPGNDKPERENPG
                     NESPNGKPNGKPSHPDRTAKESEKNGTQGLPKTGEFNNPLLALAGGILLIGVVVYVMK
                     QRKK"
     gene            complement(49110..49655)
                     /locus_tag="ACG8LA_000415"
     CDS             complement(49110..49655)
                     /locus_tag="ACG8LA_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase family protein"
                     /protein_id="HFQ0202749.1"
                     /translation="MNALISIDYTYDFVAEDGKLTTGTAGQVIEKKLTAHTKKFIDQK
                     DFVVFAIDAHDPKDSFHPENRLFPPHNVIGTGGRELYGSLKSLYQDYEQEENVYWIDK
                     RHYSAFSGTDLDIRLRERQITDIYLTGVCTDICVLHTAVDAYNLGYKLHIFKDSVASF
                     DPVGHEWALRHFESTLGAEIL"
     gene            complement(49667..50359)
                     /locus_tag="ACG8LA_000416"
     CDS             complement(49667..50359)
                     /locus_tag="ACG8LA_000416"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008782 - adenosylhomocysteine
                     nucleosidase activity [Evidence IEA];
                     GO_function: GO:0008930 - methylthioadenosine nucleosidase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009164 - nucleoside catabolic process
                     [Evidence IEA];
                     GO_process: GO:0019509 - L-methionine salvage from
                     methylthioadenosine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HFQ0202750.1"
                     /translation="MKIGIIGAMEEEVKILRENLSEPLSWERAGALFISGSLGNHEVI
                     VVRSGIGKVLASITTSLLIQQYGVNMVINTGSAGGIGEGLQVGDIVISDKVAYFDADA
                     TGFGYNPGQLPGMPLYYEASTYLRSEMVKAAKATNLNAKEGLIVTGDTFVDSPDKIKE
                     ILTNFPEALACEMEGAAVGQTARQFNIPFLIVRAMSDTADHSATQSFDEFIEDAGKRS
                     AEMVIEFVKHLV"
     gene            complement(50378..50662)
                     /gene="macP"
                     /locus_tag="ACG8LA_000417"
     CDS             complement(50378..50662)
                     /gene="macP"
                     /locus_tag="ACG8LA_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall synthase accessory phosphoprotein
                     MacP"
                     /protein_id="HFQ0202751.1"
                     /translation="MAKGPLITRSELRKRQQAQASESLKKQRKAETAYQQEEKKIASF
                     YRKESKKNKPITKTRISEREKTTKWNSFLMKSLIIVILMLCVVFLAIAFI"
     gene            complement(50675..51238)
                     /locus_tag="ACG8LA_000418"
     CDS             complement(50675..51238)
                     /locus_tag="ACG8LA_000418"
                     /EC_number="3.6.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HFQ0202752.1"
                     /translation="MLNNEQFEEKTISRKEIYSGKIIDVAVDEVRLPDGGTSKRELVF
                     HPGGVGIIAFDEQDRLLLVKQFRKPLEKVILEIPAGKIDPGEGQNPEMTAARELEEET
                     GYRAKSLSHLTSMYLSPGFANEVLHIYHAQGVEKVENPLAQDEDEVLELYHLTLEEAQ
                     QAMKDQLICDAKTIYAIQYWELLTKGK"
     gene            51466..52128
                     /locus_tag="ACG8LA_000419"
     CDS             51466..52128
                     /locus_tag="ACG8LA_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-bromo-4-chloroindolyl phosphate hydrolysis
                     family protein"
                     /protein_id="HFQ0202753.1"
                     /translation="MIKRNWPWLLALVLLFLFVRNNSFSFVLGLLLIGVVLVLWGLFG
                     SRRKKGKQEEIPALTDELETHYEKSGMTANEISFFRQTMNQTKNEINQLQMNMQQTAK
                     LKAIDLRHDPVKAAKALFKELVKEPNRLHEASQFLYTHLPNLVDLTNKYNEINDHEIK
                     NKQTYEKLEESAQIIDQLSALIAQDYQKFVAEDLDDIDVEISVAKQSLKRDNKYEPEQ
                     KD"
     gene            52252..53448
                     /locus_tag="ACG8LA_000420"
     CDS             52252..53448
                     /locus_tag="ACG8LA_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HFQ0202754.1"
                     /translation="MDHKPTETKDVTPVNDTLEDLLNNPFSTPTDTLTTSQQAEIDQL
                     QEQQTAARLIDKLPAERQEQAKQLAAKIDANDAQSVISYGSAAQAKLSEFSQSMLNHV
                     QAQDIGPVGDSLTELMYRLQEANPDELRAGEGNIFQRVFGKVKQSIYEVTAKYQKIGA
                     QIDKISVKLDKEKDGLLKDNLMLEQLYQKNKDYFDALNIYIAAGELKMEELQTTIIPE
                     AMKRAEETGDQMDVQIANDYTQFLDRLDKRTHDLRLARQITIQQAPQIRLIQNTNQAL
                     AEKIQASIATAIPLWKNQVVIALTLLRQKDAVTAQRQVSETTNDLLKKNSEMLKISAI
                     ETAKENERGIVDIETLQTTQNDLIETIQETLRIQKEGKEKRRHAEVELGHMEEDLKQK
                     LLDLTQ"
     gene            complement(53549..54925)
                     /locus_tag="ACG8LA_000421"
     CDS             complement(53549..54925)
                     /locus_tag="ACG8LA_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFQ0202755.1"
                     /translation="MDLFRKKEINLNHTSEMKKELKTSDLIMLGIGAIIGTGIFVVTG
                     VAANQNAGPALSLSFVLAAIVVILSGLSFAEFASRVPVIGGPYAYLYVVFGEFAAWLT
                     GWLLIGEFLLAVSSVASGWSGYMQGFLKSLGAELPQALTGGYNPENGTYIDLIAVLVV
                     IFVTYIVSLEAKKALRLNNAMVYVKFGIIALFIIVGIFFVKPDNWQPFMPFGFSGVLD
                     GAALVFFAFLGFDAVAMAAEEVKNPQKDVPRGIIGSILIATVLYIIVTLILTGIVPYT
                     ELGVNDPVAFAMRYVGHGTVGAVIAVGAILTLLTVTISMMYSLARLLFAVSKDGLLPK
                     FMTEIDQKHRTPKKATYAAGVAAVFFAGFFPLNVLAELTNIMALAYLMLVSLGLLKLR
                     KMFGKPKAGEFKVPFVPLLPIVSILTCIVLMLRLQTVTWIVFGIVMVIGLIIYFGYGY
                     GHSKMNEK"
     gene            complement(54962..55828)
                     /locus_tag="ACG8LA_000422"
     CDS             complement(54962..55828)
                     /locus_tag="ACG8LA_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GRP family sugar transporter"
                     /protein_id="HFQ0202756.1"
                     /translation="MEILIALVPMLAWGSIGLVSGKIGGDANQQTLGMTIGAFLFSLV
                     VFFVVSPVITPWIFLIGFLSGLAWSVGQNGQFHGMKYMGVSVGLPLSTGFQLILNTIA
                     GAVFFHEWTQTKDYVYGIIALALLVSGAYLTARQDDEGKIDTDNKMLDFGKGFRALIF
                     STIGYGVYTIIVNWANLDAMSIILPQSIGMILGASFFAFRKVKVDQFVWKNMICGLLW
                     GLGNICMLLTVKSLGLAVGFSLSQMGIIISTLGGIFILGERKTKKELIYVIVGCLLVI
                     LGGILLGYMKTV"
     gene            complement(55917..56942)
                     /locus_tag="ACG8LA_000423"
     CDS             complement(55917..56942)
                     /locus_tag="ACG8LA_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFQ0202757.1"
                     /translation="MNFFKYLKDQWTLILGWLFFIALTIFVMWLAPNIKVDLSTIAYL
                     ALIEGVFLIFYLLGGYLSKRRWWGKLADIQKTSPLQNYLSGGRTEEEKLVEEYINQLI
                     REHQEVMQSAISNQQDQKDYIDSWVHEIKVPLSASKLLVRSIEFDIDDQKYTLLENEL
                     SKIDEYVEQVLYYARLDSFSRDYLIQEYGLKGIIQPVIRSQANYFIQKNIRYEIVGED
                     HTVLTDAKWIAFIFNQLLSNAIKYTPDHGNIIVSIEKEAQGVSLSVKDSGIGIPAEDL
                     KRIFDKGFTGRNGRLSKTHSTGLGLYLAKNLAEKLGIHLTAESTEGKGTTMTLFFPIL
                     NFYNEKR"
     gene            complement(56960..57634)
                     /locus_tag="ACG8LA_000424"
     CDS             complement(56960..57634)
                     /locus_tag="ACG8LA_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFQ0202758.1"
                     /translation="MAKIMVVEDEEIIRQLIMEELEKWQFETFGTTDFNQVFSDFERE
                     EPQLVLLDINLPVLDGYYWCQKIREVSKVPIIFISSRNTNMDMIMAMNMGADDFVTKH
                     FQIDVLIAKINALLRRSYNYTELSSEMMSHNGITLNVDNGSMEINGEIIDLSKNEYRL
                     LFILMKHNGKILSREKLLRALWDDERFVDDNTLTVNINRLRRKIEQAGIQGYIETKVG
                     QGYIVP"
     gene            complement(57818..58711)
                     /locus_tag="ACG8LA_000425"
     CDS             complement(57818..58711)
                     /locus_tag="ACG8LA_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HFQ0202759.1"
                     /translation="MKKKIGNRPQTQISLLLQLFMAVMFLAGAAVFTYPFLADALSNY
                     LDQRRIENYQKQLERDKEEKHEQQLAVHEKKNQTLAHTSVIPGMGQVKDPFEQAVRNV
                     QNPGKEYYEQHMIGAIYIPKINVSLPLFDETNDLLLDRGATVLQGTSFPTGGESTHSV
                     ITAHSGIAEKKLFTDLEEMEQDDRFYLEVYGRMLAYEVVEKIVVLPTKTNTLAIREKQ
                     DLVTLITCTPYTVNTHRLLVTGRRVPFTEEVSSKIEQTKKYHLYRLLILLLGILLVLT
                     LFGYWCYRKFKRQKQRKKNNR"
     gene            complement(58785..60482)
                     /locus_tag="ACG8LA_000426"
     CDS             complement(58785..60482)
                     /locus_tag="ACG8LA_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HFQ0202760.1"
                     /translation="MNKKMIVTGMSVLLLVTAGIGIFGNGKLVKAEEVAQKPSEVTIT
                     LHKKGFSSVPEERPNSGLVSTDFGEENIPGVDFDLFDVTEVYYDLIRDNPLTPEREDG
                     LNSAEAIEWIQKRHTESWFLKYRLTSIDKQTTNEAGEAVFSTVQVTEEAPSSRDKVYL
                     FLETYSPAHISRIASPMVVMMPVMMPDMVDGVWDGSTWKDTYNTDVHLYPKNEIREAD
                     KQMNVEESDLRQVTIINEAGEQETISYIDLERGKTASYTITAPIPYFIDSVLENGSAV
                     IKNYKITDTPTVGLTYYDQEIEVRAGETILTKGQDYIVEVVSNGFVVTILTEENGVAK
                     VDTLGRLADARGGDLTITYNLKVSTELEADDFHNNTAVIEIGRNDEFDYEEGVEPPEK
                     VTTGGRKFEKYDASSSELLKDARFELWNEDRSEYAIFYKGESPLAVYESGADRIEWAT
                     SGQATEFVADGNGYFEVQGLDYGTYQMKETMAPEGYVLPTGEAAFTEFIISYGSYNEE
                     IQIVGVENPGPERVPNMKRGSLPATGGNGLLAFLLIGISLMIGAYSWYRKSKMKSEV"
     gene            complement(60475..61788)
                     /locus_tag="ACG8LA_000427"
     CDS             complement(60475..61788)
                     /locus_tag="ACG8LA_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pilin N-terminal domain-containing protein"
                     /protein_id="HFQ0202761.1"
                     /translation="MKKLLCLMLQLLVLLPLAAVLLPHAMSAEESGEDVVEFVLHKRM
                     IRDIDYNDQFEYHENDGLAISEEAGETADIISQTVPLNGATFAIYDMTDYYHEKKAAE
                     NMTPKEFVQQIAETNRNNIRQLITEERLVQIGTSVTTGKDTVGGLGDGIARIKAPKKN
                     QDRDAVYLIFEESIDPEVGLDVDIDQTAIPIAAILPIYHPTESTEELQEIHIYPKNVG
                     YLRDPYFFKYGRQRGTTEKGKPLEGAVFALYQMIEGGKYYLDMAPANDLKNQWIKPAD
                     NDPLNDKNVSKFISDKEGLVTTGQRFLPSGTYYFEELKGVEGYEMDEASKRIEVIIPE
                     FWVDAKGQPQYVVVNGQEMAELESGKVPVSAYESATPRVYNETVKETTDKPKEPSGPS
                     NPGQSGKWSVFPQTNEARTLISLLGILLLLGAVLLIKKERGEKNE"
     gene            complement(61788..65729)
                     /locus_tag="ACG8LA_000428"
     CDS             complement(61788..65729)
                     /locus_tag="ACG8LA_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaA isopeptide-forming pilin-related protein"
                     /protein_id="HFQ0202762.1"
                     /translation="MEKLDEPIVPSGQALQRIQRQLFNGILERLGPTATQDPYEYIYP
                     SGEVENEQHRYPKFTTNDYTKVLGNWTQSNERYQGDKGSPYDGENLIDDSDYTNGGAN
                     WRNYDYATNNGSTAGEEDRNVPAQTVQLWGNERNFENSYLDYNGAYIKKWVEPVLPSS
                     TASDLHPEDATTLYNVYLDVIGGEKKEISPIDIVFVLDKSASMSELTAGTNSQTKNAA
                     LIEAVNEMSKDLLSDPSLDIRIGMVNFYHNSTAINNHEQISSDIFPLTNDINRLTGSE
                     NTALNRTPIGGTPLTLGLKNGYETLYKDNGGENRNPEKILIVVGDGTPTFSYAPIQSS
                     YRTSTNGAWSNWTVMEDKIAEDNDVLFRNFEEFSGNTSNAGFTHPVTYASDFNRPEDE
                     VNVHYRYGEVKEGDNKATHWVGDGSSNNNTNGSPTSQEKSSAINTVAYHHWLKNKYQE
                     NPPSIFSIGLGIDGNVSGRQRLDAIGRNVLKNIADLEEDGVTPRYYNANNKNDIVTAL
                     EDISSTFKRTIQQATLYDETGFNVSPFGAGRSADIQFYHLDPGENGMKYQEPEIWDEE
                     RHGQAPPEVVATPTTYVGRENQAYKFSPISLGEGEMVRIKYQVKLDAGAQDGNFCTVN
                     NMAYIQNLEDYENDITTGRMYFPSSSIRYEHKGRNFQVSKKGQNGEPLAGVEFALYDQ
                     NPESGEAEPIETSKTTTDGIAIFETKMPILGDETGAVSDIFWIREIAGPPRYQLVDET
                     YQFQIKKYAANEDEMLGHYELVDEYTSGSRVGGPEGKDPNSYYEGEYHKLSVVQEPNI
                     EGTEYDELYVKLEMRNEFKPIHMNINKLIEGSNMPINGAEFELYETDGNGLEIGYPVA
                     KGLSGVNEVEEEKGRLTFYSVDEDGKYVIVDGEKVIHPIGEPDSFVYKDSEETTNYAE
                     YKIIESQNPEGFKEPDENDTWILRLYDNAIGTIQLKQTGEENWQYLTYTTDEEDRLWV
                     AFTAYNTFDYREIRVRKLDHEGHTLDGAGFDIRKVGDSSFPLYRAYTGNPLEPEESKR
                     LPGIGYFYSRAVGVEKYVDLNYDQPLHLSIGEYEVSESVAPNGYRLSDQVFQFALNEE
                     GKFIIEDTVIEDETAPLPEGYEIIDGVLQVTLEDELAPIDLELLKIDSMNSRRLEGAE
                     FSIEKQNSAGEYEIIEGGLAPDPNDSSLFNASDLLEGVYRIKEVKSPDSYRKLPGYFI
                     LEISYREEPDIENDRVVPGKEAGTLKVEISYYPNEEAETPDLQQELEYELLETNRIRL
                     QLSVGNDPENPLPATGGSGRLFYILLAAFFMALAGAAYGLFVRQSKKEGAR"
     gene            complement(65838..66296)
                     /locus_tag="ACG8LA_000429"
     CDS             complement(65838..66296)
                     /locus_tag="ACG8LA_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFQ0202763.1"
                     /translation="MKGLKLKLLQLVTVSLLFGPYFQSVYHMTTLDVAAESTETKEDE
                     VFLDEDYAKIEGKYIEKEETLEWHLAFEKKESANEGRIRLAIDAAAAGIGTVKNVRGT
                     GLSSYDEDGEDLKVETIDGQEWYVGKVYSKEAETGTLIFETEKIPDVNEG"
     gene            complement(66594..67112)
                     /locus_tag="ACG8LA_000430"
     CDS             complement(66594..67112)
                     /locus_tag="ACG8LA_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HFQ0202764.1"
                     /translation="MLRLIAKIDDSIINKFAKQRKTDSRKINFLKFISNISNGGFIWL
                     LLAAVLVLIPDTREYGLAILIGSLIYFFVGLLFIKKTTRRKRPYEKNRRLVLYTSKPK
                     TSSFPSGHTALAFLSVAALFELSPVAGILAFLFACLIAYSRIFLLLHYPTDILGGAIL
                     GSVIGILCAAVI"
     gene            complement(67114..67731)
                     /locus_tag="ACG8LA_000431"
     CDS             complement(67114..67731)
                     /locus_tag="ACG8LA_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HFQ0202765.1"
                     /translation="MMNRSIGKKANDYFLEIIEWIPRLIHLQLLWFLCVLPVFTLGTA
                     SRTVLYMIYHYKKNEEKKLGSLFWKKFRENFSLYGKQDSLASVYFLLLLIDYQIFRYW
                     GGGIGYTLMYTTLFLLLLSALLFSYKILLQLEQKEASWITAFFLFFNDFKSALFYLAG
                     TLILLVAFWFAGPIYFALLGFSFLFYFQVLLFIHRTQEKVLKKEE"
     gene            complement(67728..68582)
                     /locus_tag="ACG8LA_000432"
     CDS             complement(67728..68582)
                     /locus_tag="ACG8LA_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFQ0202766.1"
                     /translation="MMDYFKKTSVNRQTKKILSYVLMTVIGIILIIPLLWMVFTSLKP
                     MEEIVRYPPTFFPEKIVWENYLDTIAAFPFWRYARNTLFITVLVVIGNVLSNSFIAYG
                     FAKLDFPGKKLMFALVLSTMMIPGFVTMIPQYVLFSKIGWVGTYLPLIVPSFFGNAFN
                     IFLMRQFYLSINNELIEAAEIDGANHLYIWSHLMLPLTKPALITIAINSFNAAWNDFL
                     GPLLYIQDQEKYTLQIGLQVFQNQATTQWNYLMAGATLVLIPTILLFFFAQRYFIEGM
                     DLTGGSKG"
     gene            complement(68579..69490)
                     /locus_tag="ACG8LA_000433"
     CDS             complement(68579..69490)
                     /locus_tag="ACG8LA_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFQ0202767.1"
                     /translation="MKRLSIRKKKEARWAYLFISPFIIGFLVFMLGPMLFSVIGSFTD
                     YNLTSKMNFIGLANFKRMFVHDDLFWKSLYNTVYFVIFNVPLTTIFSVFLATVLNQKI
                     KGISVFRTAFYLPAVLSGVAVYILWMQLLSPSAGLINTFLGWFHIPGPAWLFDPQWTK
                     PALILMKIWSSGGAMLLYLATLQNVPRSLYESAEIDGAGVWGKFKSITLPLITPIIFY
                     DVITSTIGSFQIFQEAYVMTKNGTGGPANSLLFYNLHMWNKAFVAFDMGYAMAMSMIL
                     FLIVLVLTFVNLKLAPKWVYYSGGDGK"
     gene            complement(69531..70865)
                     /locus_tag="ACG8LA_000434"
     CDS             complement(69531..70865)
                     /locus_tag="ACG8LA_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFQ0202768.1"
                     /translation="MKKLLFTGLLASSALFLLGGCGSSNASDASSSAANSSEKTSDGR
                     KNIDFWSFWGSGARKEAIEEIIEDFNQSQNEIHVNYKYQPWGDIWTKSLSAITAGNAP
                     DVIVQDINSVAQRAEAQQATNLSKYVEKDTSKDFYPQLWDTVEYEGDPYAIPFNTDTQ
                     VIFYNKKLFKEAGISEQDLPTTWDELEETARKLDKKEGKEFTRIGFYPLWNLGADVWA
                     LNADNGTSWFDKDEKVKIDTKNKVEALEWIQDWQDYYGKNTINKLEAEFGSGVSDPFI
                     SGLVAMRAQNINYYSSLMENAPDDFDFGVMQLPEKEEGSGHWSWGGGFVLEVPYGAKD
                     PEASYEFIKYLSSPEVQEKFGEKSFDIMASKTANENLVNNDNLTDKGKMIYQMADENF
                     KNTVITPVPLDAPDYTTLVNEQIDQILLGTKSPKEGLADAQKAVENLVKQNQ"
     gene            71073..71903
                     /locus_tag="ACG8LA_000435"
     CDS             71073..71903
                     /locus_tag="ACG8LA_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HFQ0202769.1"
                     /translation="MFRHQKELQFEAKPDRPNPLIAKYLQELIGGQYGEMSVAMQYLF
                     QGWSCRGEEKYKDMLMDIATEEIGHVEMLATMVARLLEGAPVEDQEAAMQKDPTIGAI
                     ISGMNPQHAIVAGLGPRPADSVGNPWSGAYIIASGNLLADFRANLNAESQGRLQVARI
                     YEMIDDRGVKDMLSVLLARDSYHQNLWECAVKELEEKEGSILVPSTFPRDKERKDIAY
                     DFYNFSEGDQSSEGSWASGKALDGEGEYQWLKEPKIEGAAPKLEPVTPKMYGTPPFKK
                     "
     gene            complement(72147..72396)
                     /locus_tag="ACG8LA_000436"
                     /pseudo
     CDS             complement(72147..72396)
                     /locus_tag="ACG8LA_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206386.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(72587..72781)
                     /locus_tag="ACG8LA_000437"
     CDS             complement(72587..72781)
                     /locus_tag="ACG8LA_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202770.1"
                     /translation="MKTTLVLFYKKHPYFTLLINILLASVIGISVEYLINKDFIGSCF
                     YTALFLGLLEAFSIYKKSKK"
     gene            complement(73286..73471)
                     /locus_tag="ACG8LA_000438"
     CDS             complement(73286..73471)
                     /locus_tag="ACG8LA_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202771.1"
                     /translation="MSKNSKGFLTILLAFIGYMLVGLLKSYSNELLNFSTFINDTLVP
                     SLFFIVFFAVGYFIIKI"
     gene            complement(74321..74662)
                     /locus_tag="ACG8LA_000439"
     CDS             complement(74321..74662)
                     /locus_tag="ACG8LA_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HFQ0202772.1"
                     /translation="MSEERIYIPKKGDIVWIDFDPSVGKEIQKRRPGLVVSRYEFNRK
                     TMFSVICPITSTIKNLPTRYSLPEELDIKGQVIITQLKSLDFKERKLKKIENLPLQDM
                     AKIDQIIQYMF"
     gene            complement(74662..74892)
                     /locus_tag="ACG8LA_000440"
     CDS             complement(74662..74892)
                     /locus_tag="ACG8LA_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HFQ0202773.1"
                     /translation="MLVTKSRLQGSSVVVTLPSDNGKKPSENQEYIVVYSDDGTITLV
                     PKIEDPFSGGEEAEYYEKDEWEDLTPEGREIL"
BASE COUNT        21758 a        15855 c        13083 g        24255 t
ORIGIN      
        1 ttatctttag aaccatttca gatacatatg aaacaattac atatgatttt ttcataaaaa
       61 aacagtactg tctagtagta taaaatatac aaatttctta aaaatttttt cactaaaatc
      121 actacctgaa acagtctaaa acacttatat atcaacgttt aatgaaacta tctccgtttc
      181 atttcagata caaataaata tagtcgggct ccaaatccga aaaaaaatac ccccagtagc
      241 ttatcctaag ctactggaga tgtataagta cggtcatata acaacggggt agggtaaata
      301 aatgaaaaag atggaagaat cattattcaa taactttttt aaatacttcg ttgtaatcag
      361 ttacctgtcc gttcttaaat accacagaat aatctttttt cccattttca agtaaccgaa
      421 gtggaatgtc tttaccaact tgctctgtca ctgcattact gatacctgtt agattagcta
      481 ataaatctga taaagattga gcatctgtag aaatctctgt atcagtattt atcgtgattc
      541 ctttatcttc atttacaagc ttccaagtag gtggtatagc tgtgtatgtt tcgatgaatg
      601 aatcaattct ttcatctatc gtcttcccag tatctacttc tgtctcatta ctcttagatg
      661 aatcgattct ttcatccatc gtctgctccg taactgcttc tgtctcatta ttctcaccgg
      721 aaactctctt cacacccaaa cttatatatt gtccatcttt agtgtgcata gttaaaattc
      781 ccacgctttt actaataaat tcactataac cagttctttc aatagagact tcaatgtatt
      841 tcacactatc atactcaaaa gaaaaataga catgtaaaag cattttgttg tttacatcta
      901 cataataatc ctttgactct acttgagacc ttcctatacg gaatacagct ttactgtctg
      961 atatctctat accagcatcc ttattattaa tctgccaatc tccaagtagc tcttctggca
     1021 agctagtagt ttcttgtgaa cactttacca cttcactggt agaggtcgaa acattcacct
     1081 ccgcactgtt agaagaattt tccaaggaat caggagcctt agcacaacca acaagtcttt
     1141 atatattgtg cagccgatat tttcttcatt cagtacaccc ttgaaatatg cagtgttaga
     1201 taaagcagtt cgtcctgatt tgctgaggca cccatctctt cttgaacgta ctccttgatt
     1261 ttcaaggccg cccgatactc tttcggaaaa cgctgcttca ctgaagccag caaaaaatca
     1321 tccttctccg gcaactcttc cttcttaatc attcgggcaa taaaaaactg taaatgcgtc
     1381 acaaatctta agtaaagcat cgaatcttta tcaacctttt tttcgggaaa cagatatcct
     1441 agcatagcca agatatcctt tagtgctctt accgagagca tggtttcttc catatttgct
     1501 tgttcacttt gggcatttac aatgtgaaac gcaatgtttc cagcctcctc ttctggcaac
     1561 tgaacattca tttttttgtt gatcaattgg atagcatagc agccgatctc aaattctttt
     1621 gggtaatact tttgaatttc aatcagcagg cgattttgaa aaacaatgcc tttttgactg
     1681 cgttcaatgg catgcttcaa gtgatcaacc aaggtaaaaa atagactttt attcagctta
     1741 aagtcaaact tggcgttggc ataatcgata attcgcttga cgcaaataat tagatcatcc
     1801 ggagcagcct caaacagttt aatgtaatcc ttttttagag catcagaaag tgaatctaat
     1861 ttaaatactt tttggatttt gtcagccgga accaaatcgc ctttctttag ttgaaatcca
     1921 atccctttcc ccatcaaaat tacttctttg ccttgcttat ctaagcaaag aattaaactg
     1981 ttgtttaacg ttttaattac tctcattaga ttcaccgttc tctctaagct aagccatttc
     2041 ttgcgattac tttttgatac caaaagaagc tttctttttt tattcgtttt aattctttaa
     2101 gattctcatc ggttcggtca acatatataa aaccataacg cttattgaag ccttgatggg
     2161 tactaacaac atcaatcgct gaccaaggta aataaccaaa aacatctaca ccatctgtta
     2221 aagctgcttg aatagccaga atatgtttgg ctagataatc aattcgatcc tggtcattaa
     2281 ttcgtctatc ttcctcaact atgtcgggtg ccccatagcc attttcagta attaaaatag
     2341 gtaaatcata gcgatcgtac aatttcctca atgttaatcg tagtccagta gggtcaacta
     2401 cccagccata tggcgtttta tctacataag gattttcagc tgcccggtag acaccttctt
     2461 ctcccaacat gatctgttga tcccccgctc tagcggaaac atctgatccg tcatttttgc
     2521 tggcagcgat ggtggcagtt gaataataat taatcgcaat aaaatcgggt ttaccggagg
     2581 ataaaattgc ctgatcctct gcctcaattt taggatataa tccacgatca ttcaaatagt
     2641 tttcaaacaa ataattgtat tttccccgaa ctgctacatc taagaaagac cagcctctca
     2701 atgtttccca attatgggct gcaattgcat cttctggact ggaggtagct tgatacatag
     2761 ccgttaaatt gattgctgga ccgatttttc ctttaagatt caactgatga tacaagtgaa
     2821 ttactctagc ttgagctaat aaaacatggt gattaatttg aaagagttct ttttttgaag
     2881 gcagctctcc acttggtggc aaaccaatcg ctccaggatg aaggatcatc gtgttttgct
     2941 cattaattgt cagccaatag ttcaccttgt caccatactc agtaagcaat acctgtacat
     3001 agtccacaaa ataatcgata gttgctcgat ttaaccaacc gccctgctcc tctagaaaat
     3061 aaggtaaatc gaaatggtac atggtgacaa tcggttcgat tccctgattc aggcattcat
     3121 caattacttg atgataaaaa gaaattccct tttgattggt tttattattt tcaatatcca
     3181 taattcgcgt ccaagcgatg gaaaagcgaa aagcttttaa gcctaattct ttaaacagct
     3241 gtatatcttc tttatagtga tggtaaaaat ccgaggcaac ttcaaaatta gctacccctt
     3301 ctgtatgctg atacttgtca ataatagacg gttgtttccc atcctcctga taggcaccct
     3361 ctgcctggta ggcactaatg gaggcacccc ataaaaactt ctctggaaat gctgaaagct
     3421 gtttgtattg cacaaaaatc ctctccttaa ctaatttgca tcaatggttc gtgttccttt
     3481 aagcttccgc ttgcttcact aattcctgcg taattttcac tgttggtcac taccacaatc
     3541 actgtatcat cgtagccagc gtttctaatg gcagcgaaat cggcgttgat taataattgt
     3601 cctgctgaca cctgatctcc tgcttttaca aatacttcaa agggttcccc ttttaaattc
     3661 acggtgtcga tccccacatg gatcaataat tcaatacctt ctttagaacg tagaccaatc
     3721 gcatgtttag attctaaaat agtaatgact tctccctcaa caggtgaata aatgctgttt
     3781 tcttctggat gaatggctac gccctttccc aatagtccct tagaaaagac agcatcgttc
     3841 acttcagaaa taggacacac ggttcctttt accggatttt caacaatgac tgcttcggct
     3901 attgccgttt gctctgattc atcagaagta tcgtcaaatc caattagata agcaatgata
     3961 aaggttgcaa caaaggcgat tacacacgta ataattgcgt gaacaatatt cattggattt
     4021 tctccaataa aggctggtaa ggctgctaag ccaggggaaa caaaggcata tctgactaaa
     4081 ccgctcaagc cagcatacaa accagcaatt gcaccaccaa tcatggaagc aactaatggt
     4141 tttttcagct tcaaggttac tccatagagt gaaggctcag taattcccat taaagcagtg
     4201 atcccagtgg acacagctag ctgcttcaac tctttgtttt tagttttcgc ggctacagca
     4261 aaggtagcac ctgattgagc aatattagaa gccagcattc ctggcccatt gatcatttca
     4321 gaacccgtac tgctcaattg catagtagcg attggcgtca ttgcccaagc tgtacccgta
     4381 accaccaaaa atggctgcaa accacccatc aaaaatggaa ttaaccaagc tgctttgccg
     4441 ttaatccatt cagcccccat tgctataaga tcgttcagca acgttccaaa cggtccaatg
     4501 acaaccaacg ctaaaggccc cataattaaa aataccagca tcggcttagt aaagaattta
     4561 ataaacgaag gcgaaattcg atccgcaaag ggctctacat aggacatgat ccaaacagta
     4621 aagataatcg gtaaaactga tcccgcataa tctgcagcta ataccggaat tcctagaaaa
     4681 gaaacggcat cgccagtaga aaaaagctgt gaaatatttg gatgaagcaa aatgccagca
     4741 acagtaatcg ccaaaattgg gttgacatca aactttatgg ctgccccata ggctaatagt
     4801 actggcataa aataaaaggc tgcatcagca atagtattca aaatgatgta agtttgacta
     4861 ctgtctgata gtacaccagt caaagtcaag acggccaaaa tggcttttac catcccggca
     4921 cctgttatag ctggaatcat cggtgtaaag gtggtagaaa tgacactaat caatcttgaa
     4981 ataatacttt cttgattgtc tgaagagggg ccctttttaa ttgaagttcc cacttccttt
     5041 tgaatttcct tgaaggctgt ttggacttca ttgccaatca ccacttggta ttgtccaccg
     5101 ctatccacca cactaattac accaagtgtt ttttctaagg ctttcgtatc ggctttcctt
     5161 ttatctttga gttcaaaacg cagtctggtg gcacaatggg ttaagctgac cacattttct
     5221 tttcccccaa cctgttgcaa tacatttctt cctacttctc tgtaatccat tattctctct
     5281 ccttaaagca gtaaaaaaga ccaagtcaaa ccacgcccca atcaacattg aagtgttagt
     5341 ttgtcttggt cttgcctgca taatcagtaa catgccaata acgttatttt gctgtaatcc
     5401 aataatagca cattatgata gcgcaatcaa cagggaattt aattttttat cttttcgttt
     5461 gaccgtatag ggtaatataa cagttagatc acatcaacta gggtatatct gcgtatactt
     5521 actgctaaaa taagtatatc taatattaac tataccagta aaaccattcc tacataacca
     5581 gcgggaaatt cccaaaatcg tgaaagcatc aaaaatgcat ataacggatc acacaacttc
     5641 aacaattctg ctcttgggaa aaattgatga atttggtgag taaaggatgg aataaacagc
     5701 attccaacaa tataggcaac aatagtgata cttgtttttt tggtaaaaat cagtaagcaa
     5761 tagccaattt caatcattcc gagatataaa ggtatcgata gaatgatttg ggctagtatt
     5821 cttaaaaatt aactagcaaa tgtttaaact gatttatttc taatctacat gtagtaagta
     5881 tttcaattcc accaattatc aataaaaata ccaaacatat ccataataat tttttctttt
     5941 tcatttcttt tatattgtta taacagtgaa taacataaaa attcccgaca atcattgtaa
     6001 tatttttttg tcacctgtat tagtatttaa tttataggaa actataaaaa ctccctagtg
     6061 aatttacacc tttgggagtt cctgtttgga cggtatgcat aatacattta aatcaattta
     6121 acattaacac ctcagcatat ggtatctcca catatatacg gtctttcttt ggatagtact
     6181 caatatttat gttgatagca cttccattgt ctaatatagc tttagcccgg tatgtgttat
     6241 ctccattttc atgagtaatc gtcacatcat cacatgatcg atttaagttg tactgttctt
     6301 gtaaaatctg tgttaccaat ggtttcgatg acttctctaa tccagatgta cctgtcattt
     6361 ttgaaaaaat gatacctata atagccaaga caacgataac tataatgata aacttcttgt
     6421 tcatatttac tttattcaac tttttatctc ctatctccaa aataatttgc tcttatccct
     6481 cttatcagta cattgacatc cctaaaagta caccaaagat tgctccagct acccctgcta
     6541 tcatcaaaat cgtacccatt tgttcatctt tatctcgata taagtagccc ataataacag
     6601 caacagcacc aaatacaaca ggaataaatg ctaacgctac taccatagaa atccaaccaa
     6661 taatcaaata cagcttccct gtctcttgtc catgtacgat ttgttccttc atttcattaa
     6721 ttgtctgctc agtacttttc tttactgcgt ctgctccagt tgtctcatct gtttcttgta
     6781 gtgctccgca aaactggcaa tacttacttt catctgttat ttctttgcca cattttctac
     6841 aatacatgtc ttctcctcct aaaaacattc aattgtttat tagttaactg tttactttat
     6901 taaatacatc agaaaacagc tcattcattg gtacacttaa tatctcagaa agcatcttca
     6961 tttgataggg tttaggaatc gttctccctg tttgccacga acttacacat tgctgtgtaa
     7021 cattcatttt tttgctaact ccgtttgaga aagtcctttt tcttttctgt atcggctgag
     7081 attacttact tttttcatga ttctcccctc ctgttttatt atatacaaca atatgatgta
     7141 tttcaactca taaaatataa aaaaacttca aataccatta caaatacaac aacttgttgt
     7201 actatactga gatgggggtg tattaatgaa acagaaacaa tatgcaaagg tcattagaga
     7261 aaagcgaaaa gctctcgggt ggacacaaaa agaattagct gaaaaaatct tctctacaca
     7321 acaggcagta gcaagatggg aaaattctgt aacagagcct aacctcgata gcttaaccgc
     7381 tctttctaga gccctaggaa cccctgtaag ccattttcta gacaatgttg tcgtagatta
     7441 tgaggaagag tttttggctc tctatcgttc tcttagcact gaagatgcag ttcgaacaat
     7501 tgactatatg aagctattaa aaaggcaaga aaatgaacgc aatcagctat tgaaagattg
     7561 aaaaataaat aacccaccga actttaacgg tgggtgtatt gagatgaaat aagattaaga
     7621 gctatggata acctgtctag tttaatacaa ttgggtcttt tctcttcctt actctccgtc
     7681 catcatctct tgttacactt gtaaattgat aaagaggaac taattcaact cctgataata
     7741 tcaattcttt tattacttca tctatccctg ctccttttgc taggtagact aaaaaactac
     7801 tacttgcttt cacattgtat agtctcttaa tatccttaga agctcgttca agagtgaatc
     7861 cttgtttaac aaagtagcct ctgttttctt ttaaagcatt ttccacgctg ttattcccaa
     7921 cattacgtag acgttcacaa acagtgttag taagttcttt ctctgtcatt agatatgttc
     7981 cttgccacga taagccctgt aaaacttcat gtgcttcatc taaaatcaat tgtttttcct
     8041 tgctaagttc tgatcgggaa ttttgaggaa atactctttt agcctctttt tcgttaaaac
     8101 atatcttaac ccattcataa gaaaaatatt gatatgtaaa atgaaatttt tccagaagtg
     8161 gaaggatatc ttcattcaat ttttgaatca cagaagttgc attaaaaacg tctaatcgat
     8221 agacattgct tctcttatga ttaaagtttc ctaacgcttt ctcttccttt aacctattta
     8281 ggtattcgag catcttcaaa ggaacatctt catcatctaa tttttttatc aatcctataa
     8341 aagtcataag tgatagtaac ttattacatt tatctatgtc ataagtttta ccatagtaaa
     8401 aactcatttt tttagctaat tgttcccccg acaaaataca agtcacactt tccttactat
     8461 catcaaaaaa attaacatca gaaagcaaga catcatagac acgtcgcatt tcctctagat
     8521 aattccttat tgtcctgaaa agtttgtctt tcattgattc aagagtgtca aaaagtactt
     8581 ttgattcctc tttcaatttt cgaaaatgtg taggatacaa gtctaggttc tctaatagcc
     8641 aattaaatgt ttctacccga ctgtctttct ttaaaattag catcacaact ccaataaaat
     8701 tttcactgat atcacaatta ctggaatgac aataaaaaat ggaatgccca gttttactgg
     8761 taaaaatact agcagaggga ttatgatcgt tgtgaaacag acatcttaag tttttacttg
     8821 acttaagtaa tttattcata tcaatggtta acaatctttc ataaatctca ttaaaagaca
     8881 tgtcggagga atcaaacagg cagtctttaa accactgttt catttcttct ttgtcgtcat
     8941 tttttatcaa cttaacaaaa tcggtttcat tgactagttc atactctctc cctgaatcac
     9001 tttgacaatt tttagaacat gtcatggtaa aatcaatcgg aagctcagta atatctaaca
     9061 tgttgtcttc attaattatt atcactgcat ctgacttata tcctccaaaa aacattctat
     9121 tcgaagcatt tacattgtca tcacacccgg ggatgttctt tttcaagtat tcgtaaacag
     9181 caaccatttt accatagtca gtaattgctt cttttaatag aaagacaatc ttgtattttt
     9241 ctagattttc agagtaccga atactttttt gtatcgcaaa cgcagaatta tgaactaaat
     9301 tgatagataa aaccttttct atgcttaagt atctactatc atctttactc aaatctacta
     9361 ccttcccctt ctcatcttta acagtgttat cgacatccag aataattact ctggtttcca
     9421 caaaactctc cttgtcattg cctttattct ttgtcttgct tggaataaat gattgtgatg
     9481 aatttagtat ctctacaaac tcatctcttg taacttctct atagttatct aaacacctat
     9541 ctcttacatc agttttttct ttttttgtaa ctggcttctc taataatttt tctttatcta
     9601 cataaattgg aatattaatc attgatgttt ccatttgtgt ttcctcctta taaaattctg
     9661 ttaaagacta aaacatacag ataataaaaa caaactcttt attactatat gttttagtct
     9721 tatttgttta ctcaaccttt ataccgttcc atgaaactat caatatcaga ttttttaaat
     9781 ctaatgaccg tatcaatttt tataacaggt aacccgtatt gagaaacata ttttctaatc
     9841 gttcctactg atacacctag atattcactt gcctgctgat agtccatata ctctagagtg
     9901 actccagaaa taatgtcttc tagcataggc tttagcactg taattatctc tttcacttgt
     9961 tgttcaactt gtatagaaac aatgctatca atgatttgta gagacatatt tccccctcct
    10021 ttcgtgattg cttgaacaaa ttttctaaga attatcttcg tattttttgc tcaaaataaa
    10081 agtattttgt tattaaccga ttaatcaaac aaaaaatgat taccagttca tcgacataca
    10141 cataatacct cgataaaaaa gaggtgtcaa tatctttgta aaatttattt acaacacccc
    10201 tttttcgagg tatactaatt ttaggaggtg tggtcaatat gataaaacgt ccaccaataa
    10261 attatttaga acgaaaaaag atactcggaa caaaaataaa agctataaga aagagtaaaa
    10321 aattaacaca accagcattt ggtcttatga ttaacaacgg tcaattaatt gacaaaaaaa
    10381 ctatctacga atgggagaag ggaacctatt taccaatacc agagcgatta tcccgaattg
    10441 ctgatttggg aaatatgagt atagaggagt tagtttgtgg caatgtagaa gaatatattt
    10501 tgggaattat tctttataga gatagcattg tactagatgg tataacattt ccagataaaa
    10561 acctgttcca gcatcttcgt caacagttcc caccagtaca ctctaattta gatacatggc
    10621 tggatagata ttccaaatta gaaccagaga tgcaagaatt tattgctaac aagacttgta
    10681 ataaagttaa aaatgaaaaa attagtcttt tcaatatctt aaaaatagaa gaattattca
    10741 tcaatgctat tgtagaagaa tttgacaata acattctttt cctcactagc agtatagaag
    10801 aactactaga aagaatggta gatgaatggc tacctattca attgaaagac atgtcttatc
    10861 ccgaagaagc tgtgagagaa attactgata atataaacaa gctagaacaa acgatttcat
    10921 caattgggaa aaaatacact aagaaaaaaa tgaagggagg tgataccatc tagtggtaag
    10981 tactccttgt aaactaagag gagatgattt catggcaaaa atatcaaagt acaaaaagaa
    11041 aaacggtcaa gtggcgtgga tgtataaagg acacattgcc accgatccac gaactggtga
    11101 aaaaataaat actacgagaa gaggttttag tagcaaacaa gaagctcaaa aagattatga
    11161 cgagtacaga catcaaatat tatacggtgt taaaaagaaa gcacctgata tgacatttga
    11221 agacctgtat aatgaatgga taactcatca gcgtaccagt gttaaagctt caacaatcgc
    11281 aatctcagta agatacgcaa ataatcaaat acttccagca tttggtaagc ttaaactatc
    11341 gaatatctct gtcccatatt gtcaaaaagt ggtagatgaa tggcacagta aatatgaaag
    11401 ttacgattat atgagaaaac agactgcaca aattttacgc tacggggttg caatgcaata
    11461 tattgacaat aatcctatgg aaaaaacact tcttccacga aaaaaagagt atgagaaaaa
    11521 tcgtaaattt tactcaaaag aggagcttaa taatttactg gatgctttta aagattttgg
    11581 taacatgaaa caatacgcct tcttcagatt attggcatac acaggtatga gaaagagtga
    11641 agtactcgct ttacagtgga aagacataga cacgtttaat aaagaactac atgtcaataa
    11701 aactcttgct gtagatgaat ttggtaaagt tataattcaa tctccgaaaa caagagcttc
    11761 tagacgagtt atctctttag atactgagac tctttctatc ctcaacaact ggaaattaca
    11821 gcaaaaagaa gagtatttaa aacttggata caatactagc tctaaagagc aacatgtttt
    11881 tacaacagtt aaaaacactc tatacattcc aaacactgtt aatgattggt taagatatat
    11941 tttgaaaaaa tataacttgc ctcgtattac acctcatggg tttagacata cacatgctag
    12001 tttattatta gaagcaggag aatctgtcaa ggtagttcaa caacgattag ggcatgaaaa
    12061 tagtaaagtg acattagaca tctatgcaca tattacaaat aatgcaccta agaaaacagg
    12121 tcaagacttt gctgatatga tggctcatca gtaaaagagc tggtcaaaat ctggtcattt
    12181 ctagtataca ggcaaaacaa aaaagctaga acccttatat atcaagggtt ctagctccta
    12241 taacaggttt acccaacact gccttccatc tcataactga tcaatcgatt gagttcgact
    12301 gcatattcca ttggaagttc tttggtgaat ggttcaacaa agcccatgac gatcatttca
    12361 gttgcttcag attcggtcag gcctcggctc atcagatagt agagttgttc ttctgagatt
    12421 tttgagactt tggcttcgtg ttctaaagag acttggctgt tgtggatctc attgaatggg
    12481 atcgtatcgg atttcgacca ttcgtccatg atgatcgtgt cacattcgat atgagagatc
    12541 gaacccgcac tgtttttggc aaaggttact tgtcctcgat agtttacttc tccgccgtct
    12601 tttgaaattg atttagagac gatagagcta gatgtatttg gtgcattgtg gatcattttt
    12661 gcacccgtat cttggatttg gtttgctcct gcaaaggcga tggagagcat ggtgcctcgt
    12721 gcaccttttc catctaagta aacacttggg tatttcatcg ttgtttttgc acctaggttt
    12781 ccgtcgatcc attcaacggt tgcgccttcg tatgcttttg ctcgtttggt tactaagttg
    12841 tacacattgt ctgaccagtt ttggatcgtt gtgtaacggc aatacgcatc ttttcttgta
    12901 aagatttcta cgatggcggc atgcaggctg ttacttgaat aagtaggtgc cgtacaacct
    12961 tcgacatagt ggatgcttgc tccttcgtca acaatgatca gcgtacgttc gaattgcccc
    13021 gtgttttccg cattgatccg gaagtacgtt tgtaatggaa catcgacttt gacgcctttt
    13081 ggcacgtaaa taaaggtccc acctgaccat acggctgaat tcagcgctgc taatttgttg
    13141 tcggttggcg gtacaagttt tgaaaagtac tctttgaata attcagggta ttctttcaaa
    13201 gcagagtcag tgtcagtaaa gacgattcct aacttttcga attcatcttt catattatgg
    13261 tacacgactt ctgattcata ttgtgcggaa gcaccggcta gataagctcg ttcagcttct
    13321 ggtataccaa tcttttcaaa tgtatctttg attttttctg gtacgtcttc ccagtcacga
    13381 gcgggtttgt cacttggttt ttggtaatat ttgatggcat cgaaatcgat gtctgaaagg
    13441 tcggggcccc atgtttgcat tggcattttg ttaaatgttt ctagagattt cagacggaat
    13501 tcaagcatcc attctggttc gcctttgatt cttgacatct cacggatcac ttcttctgtc
    13561 aagccttctc ctgtactgaa aaccggttcg acatcatcgt gaaacccgaa tttatattct
    13621 tctaattctg gtacgcccat gttctcactc ctcttccttg tggtaatgat ggaaagctgc
    13681 ggtaccatcg ttttccattg cttttcctag tgctttccag gcaagtgtcg cacatttgat
    13741 ccgagcggga aatttagcta caccaccaag catagcagca tcgcctaatt ggtcgggatc
    13801 tttgacttct tttccttgga caagctgtag aaagtctaca gttaaatgtt ctgcttcttc
    13861 tattgatttt ccgatgacgg cgtctgtcat catcgaggca cttgccgtac tgatggagca
    13921 gccactgccg tcaaaggcga tatttttgat gattccgtct tttacatcga cttgcaattc
    13981 gatcacatct ccacatgtgg ggttgttcaa ttcgatcttg cttgtcgagt cagtcaagct
    14041 tccacgatga tgcggatggg aagaatgatc caagatcact tgacggtata aattgtctaa
    14101 tttagatagt cccatgttgg aaaaactcct ttgttgccat gattgcttca actaaacggt
    14161 cggcgtcttg cgttgtgttg tagaaataaa agctcgcgcg agcagtcgct gatacttcaa
    14221 ggtacttcaa tagcggttgc gcacaatgat gacctgctct gacggctacc ccttccatgt
    14281 ctaaagctgt cgcgacatca tggggatgta acccatccaa attgaatgca acgactcctg
    14341 tccgaaaatt cgggtcttgt ggaccataaa cagtcaatcc atcaattgct tgtaattttg
    14401 gcaacacata agcggctagt tcttcttcat atcgatggat attgtccata ccgagttttt
    14461 gcaaataatc gattgcatgg cctaatgcga tagcgccggc gatatttggt gtccctgctt
    14521 cgaatttcca aggtagttct ttccatgtac tgtcgtataa ttcgacaaaa tcgatcattt
    14581 cgccaccaaa ttcaacaggt tccatttctt ctaaccattt tcgtttacca tataaaacac
    14641 caatacctgt tggtccgcac attttgtgtc cgctgaaagc aaagaaatca cagtctagtg
    14701 cttggacatc aatggccatg tgcggggcag attgagcacc atctactacg atgaccccgc
    14761 cgttttcatg gacaagttca gctaattctt gaacaggatt gaagacacct aagacattgg
    14821 atacatgagc aatggagacg attttggttt tgtccgtaat ctttttcgct gcatcctcca
    14881 tatccaggaa gccttcttct gttagttcga tatatttcaa gacagcacct gttcgttttg
    14941 ccaactgctg ccacgggata acattagaat gatgttccat gtaagagagc actatctcgt
    15001 ctcctgcttt gatatagcgg tcgccgaagg ttctggctac ccaattcaag cttgtcgtcg
    15061 taccacgagt aaacagcact tctgctgttt cttttgcatg gatgaacgcc cgtacttttt
    15121 ctcttgcttg ttcataatca tgggtcgcgc gttctgctaa cgtatggaca ccgcgatgaa
    15181 cattggcgtt atcgtgttcg taatagtacg ctaatgcctg gagtacttgt tttggctttt
    15241 gggtcgtcgc tgcattatcc agataaacta aaggttcatc attgacgtct tgaaataaga
    15301 taggaaaatc attgcgtagc tttttagcat cgatcatcca ttcaacttcc cttcgattac
    15361 ttcgactaat tctttccgaa cttgttctac agggattgct gttaagacag aaccgaggaa
    15421 tcctcgaatc actaagcgct ctgcttcttc tttatgcaat cctctactca tcagatagta
    15481 catttcttct ggatcaactc gtcctacact ggcagcatgt ccagcagtta cttcgttttc
    15541 atcgatcaaa agaataggat tcgcatcacc acgtgcttta tcagaaagca tcaagacacg
    15601 actttcttgt tgggcatctg caccttttgc ccctttcaag atgtggccga taccattaaa
    15661 ggtcaatgtt cctttttctc ggatcactcc gtgttgcaaa atatgcccga tcgtatgagg
    15721 ggctttattg gttactcgtg tatcgattcc ttggatttgt ctgcccgagc tgattgccac
    15781 gattttgact tctgcgtgtg caccttctcc tgctaaatct gagtcaaagt cagcgatcac
    15841 atgaccgtca ttcatgacac caattgccca gtcgacagaa gcatctcgta aaatgtgccc
    15901 acggcgattc atataagaag taatattttc tcctaattga tctacggctg aatatttgat
    15961 ttttgaacca gctttagcga tgacttccac gatgatatta cctgatgatt ttgctacttg
    16021 ttctttggtt gtctggaaac gttccagata agaaaattca ctatgttcat ctgccacgat
    16081 caacacatgc ttgaagaagt gctcatcgga tgcgccatct tgaatgaata aggactcgag
    16141 tggttcatcg atcacgacat ttttaggcac atacaggaaa ataccgctgt tcataaaagc
    16201 tacatggagt gcagtcaatt ggtcttcgtt catgtttact gcttttttca tataatattc
    16261 ttggactagt tctggatatt cgatcattgc agtgaacaag tcggtaaaaa tgactccttt
    16321 ttctgctaat tccacaggca gttgttcaaa aatcgtccat gaaccttgtt ggacaagcac
    16381 aggattgtct ttcattgcat caaatgccgg aatcgtgcct gtttcactga tggtttgtgt
    16441 ttctttcaca tcaaataacg accagcgatg gaatttcacc cgatcgatat gcggcaatgg
    16501 cagttcatct gctttcgcta gtgcgtcttg acggaaggtt ctcatccaat caggttcgcc
    16561 tttacttaaa gaaaaatcat ttaccgcgtc aagataatcg agccagtttt tttctttcat
    16621 tcttgctccc ccttacgctt cttcttcttt atagtcgatt cctaattctt tactgatacc
    16681 agcgtagcct tctgcttcca gacgtttagc taggtcagca ttccctgtca tgactactcg
    16741 gccttccatc atgatgtgaa cgacatcagg tgtgatatag ttcaataatc gttgatagtg
    16801 ggtgatgatc aatgcaccga aattgtctcc gcgcatttca tttactcctt tagcaacgac
    16861 tttcaaagca tcgatatcca gacctgaatc gatttcgtct aaaattgcaa atgtaggttc
    16921 taacatcaac aattgcagga tctcattccg tttcttttct ccgccagaaa aaccttcgtt
    16981 cagataacgt tcagccattt cttctggcat atttagtaaa gccatttttt catctaactt
    17041 tttcaaaaat gccataacag aaattttgtc gttttcatca cgtttcgcat tgatcgctgc
    17101 acgcatgaat tccgcattcg tgatacctgg tatctcactt ggatattgca tagctaaaaa
    17161 taagccaagt cgcgcacgtt catctacttc caagtctaaa acatttttcc cgtcaaacaa
    17221 aatttcgcct tctgttactt catagtttgg attgcccatg atagcggcag ataaggtaga
    17281 ttttcctgtg ccgttaggtc ccatgatggc atggatttct ccggttttca ttgttaggtt
    17341 tacgccttta aggatttctt tttcctcgat cgacacatgt agatttttta tttctaagac
    17401 agacatgcat tataccccca aattctcttt cgttctcact cattttagac taattgagaa
    17461 tgaagcgcaa tgaccttcct tactaaaatc aaatatcttt tatttattat taaacaattt
    17521 tgatttctaa attagaatag gtataaaaaa gatgagaaat aagccattac agacttattt
    17581 ctcatctttt ttgttccata ccttattttg catcagcctt tactggttta acagagccgc
    17641 cccatttgtc tgtgatccat tcttggactt ctttgcggtg aagcacttca atcagttttt
    17701 tgattttgtc actgtcttca tcacctttac gagtcgcaat aatattcacg taaggagagt
    17761 tgtccttttc aagcaatacg gcatcttcta atggattcaa ccctgcgccg taagcgaagt
    17821 ttgcgttgat tgcaactagg tcaccttcat cattttggta cgtagaagct aaaagtgatg
    17881 ggtcgatcgt atggttgaac ttcaagttct tagggttttc ttcaatatca tcgaatgttg
    17941 ctgtttccag atctactcca tctttgactt tgactaagcc agcatcttgt agaattgtga
    18001 tgatgcgtcc ccagtctgat tcagaatttg aagtaatgat tgttgcacca tcttttaatt
    18061 cggaaacatc tttgactttt ttagagtaca agcccattgg ttcgatgtgg acagcaccgg
    18121 cattgacaaa gtcatatcct ttttctttga tttctttgtt caaataagga atatgctgga
    18181 agtaattggc atcaatgtcg ccttcttcca aagattggtt cggtaataca tagtcatcga
    18241 atttgacgat ttcaagatcg attccttcat ctttcaataa tggtttcaca tgttccaaaa
    18301 tctctgcgtg cggtgtcggt gaagcgccga ctttcaatgt cgtgtcgtct gctttatttg
    18361 ctgaatcttt gctgtcgctg ttgttaccgc atgctgctaa tcctacagtc agcaaaagcg
    18421 ctgctgcaaa tccaaaaatt ttctttttca tatcctacat ccccctatat cctattatct
    18481 tttgtctgtt ttcttagtta agaaatcacc gattccttga acgataaata cgattagtaa
    18541 aataattaaa gtcgcaacga atgtcactgt tagattacca cgctggtagc cttcctgcca
    18601 agcaagacct ccaagtccac ctgcgccgat cgcgccggcc atcgcagtaa atccgatcat
    18661 cgagatcgtt gtaactgtta atccagaaat caatgcggga atactttcag gtatcaagac
    18721 cttccagatg atttcccagt aacttgctcc cattgcatct gctgcttcca gtacaccagg
    18781 gctgacttca cgaaaagcaa tctctactag acgggcataa aatggtgctg cggataaaac
    18841 aagagctgga atggctgctt gcgcacctag catagtgcct acgattgctt tagtaaatgg
    18901 aatgatcaaa accatcagga tcataaatgg cgttgaccgg aaaatattac tgatgatcga
    18961 tacgattcca taaatgattc gagcatacgg tttgtttttg cgtccaatag agtaaaggat
    19021 caatcccaaa actaatccga tgatcgtcac taagaccatt gagattaatg tcatatatag
    19081 tgtatcaagg atagcctgat tcatcgtttc cgggttgatt tgtttaaaat ctagatatgt
    19141 ttctgaaaag cttttatcca cgatggatca cctcaattcc tactccttgt tctttgatga
    19201 acacttctgc ttgatctaat tctttggttt caccagtcat caagacagtc aatgaaccaa
    19261 aggaaccttc tttcacttgt ttgatctttc catacacaac gttgacatcg atgttatagc
    19321 gtcgaatcgc ttgggaaatg actggctcgt tggcatttct ttcgctaaag gtcaaagttg
    19381 ccaaacggcc gcttggattt tctttgatga gttcagctaa tagttctgtc gaatcagctt
    19441 ctggttcgat gtcttgttgt acaaagcgtt tggttacttc ttttttcggt tgtctgaaga
    19501 cagtcaatac gtctccttct tctacgactt tccccaactc catcacagcg actttgttgc
    19561 agattttgcg gatcacattc atttcatgtg tgatcaagac gatggtcaaa ttcaatttct
    19621 tattgatcgc taacaataag tctaatactt cttctgttgt ttgcgggtcc aatgcgctag
    19681 tagcctcatc acaaagcagg atctcaggat catttgccaa tgctcgtgcg ataccgacgc
    19741 gttgtttctg tccgccggaa agttgtgaag gatatgcttg tccgcgtcct tctaacccga
    19801 ctaaacgcaa cagttcttct gcccgttctt tacgtttgct ctttggtacg ccagctaatt
    19861 ccagcggcag ctggatattt tcaagtacag ttcttgacca taacaggttg aaatgctgga
    19921 agatcatacc gattttcttt cggaatgtac gtaattcttt gttttttaat tttgtaatat
    19981 cttgatcgtt tacgatcact tcgccgctcg tgggaagctc aagtccattc aggagacgga
    20041 ctaatgtact ttttcctgcg ccagaatagc cgacgattcc ataaatatcc cctttttcaa
    20101 cgtttagtga aacgtcattg acggcttgga tgtttccgtt tttcccattg aatgtctttt
    20161 tgacattcgt tagttggatt aatgacatgc cattcacatc tttctcttat aatttttcaa
    20221 acaaaaaagc cttcgccctc ttgccttaag caaaaggacg aaagcttgaa cttccgtgtt
    20281 accaccttga tttaccgtta cttcgcaata acagcctctt ccagtacttg gacttagctt
    20341 ctttccgtat actgtcgcgc tgtaacgggc actcccgtag taagtttgct tacgctcgct
    20401 tactctgctc taagaccatc ttccatctca ttttcgttac ccattttcag caaacagggc
    20461 tctcttcaaa cgtccgtgac atgtactctt cttttcaaag ctttctcgtt tcatatagga
    20521 ttgcttatga ttatagcaac tggaagaatc agtgtcaact tttttcaagt gattttctga
    20581 ttttataatt cgtcaaattc ttttggatca acatctttga aacttaagat ccacgcattc
    20641 atttcatctg aatcattcaa gatattgata tcttcaccga ttttatcatt aacagaagaa
    20701 actgtacccg ttagcgggct ggcaaattca ttgaccgctt tttccgcttc aacttcgatc
    20761 agaggttcat ctttttttag cgattgtcct gcttttggca gattggcaaa cgtgatgtct
    20821 ccaagttctt cttgcgcttc atttgtcaaa ccaacacagt attcttttcc attaaataag
    20881 atccaaaggt tgtccttttt cttcaaatgc ttgcctgcca ttttatatca gttctccttc
    20941 ataaattttt tcattgaatc caattgcaac aagctggtcc tctcgtaaga tcagtggtcg
    21001 cttgatcagc ataccatctg tcgataagac ttggctcgct tttgaagccg taaactcgcc
    21061 tacttgatct ttcagtccaa gttcccgata tttcatcccg cttgtgttga acaggcgacg
    21121 gattggtact tgactcgttt ctagccaagt ctcaatcgtt gaggccttcg gtacttcttt
    21181 gatcatatca acggtttgat aactaacgcc atgctggtct aaccacgctt tggctttttt
    21241 gcatgttgaa catttcgggt accagtaaaa ggtgtacaat tttcttacct ccttgaagat
    21301 cttgcaggtg cttcattttg gtatctcatc gataatatca acccgatacc gatcatgttc
    21361 cctaaaatcg aggatcctcc ctgactaatg aaaggcaatg ggatccctgt taaaggaagt
    21421 aatccgatat ttgctccaat attctcaaag acatggaaca gcagcatcat gatcaaaccg
    21481 cttgcgatat aggcgtaaaa ttcattattc gtatcgaaac acacccgaat catacgatag
    21541 attaaaataa aatacaagaa aatgacgaat gcaccaccga taaagccgaa gttttcaccg
    21601 ataacggtaa aaatcatatc ggactcacga acaggcacat agatattgct tacgttgaat
    21661 cctttaccaa acaagccacc ggtaccaatt gccaaaagtc cttgggccgg ctgataactc
    21721 attcctgacg tatcatggaa agggtccagc catgaatcaa tacgtgcaaa ctgataagat
    21781 ttgaatccaa ctttataaag caagtctctt ccgccttcag tcgtaaccaa gaagatcgtt
    21841 cctgctccaa cgactactgc caagattact acaggtgcga tgatgcgcca agagattcca
    21901 gacatcagga aaatcccgcc aaagatcgca agaaagacaa gcatcgttcc aaagtcatct
    21961 tgggccatga tcaatgctaa aaccggtatt gtcacgatca agagcttccc aatcagccaa
    22021 aagtccgatt tcatcgtccg ttcttttact tgcgtattat gtttagttac gatcagtgcc
    22081 atcatcaaga tgtacgcaat cttcatcaac tctgctggct ggaaagtaaa cgcaccgaat
    22141 cgaaaccagt ttttagaccc tgttgaagca gctaaattct gatcatagaa tttgagcaag
    22201 agtcccatta ccactaaccc caaaccataa aggtaaggag tcagtttcca gatccatttg
    22261 gaattcaaat gcatgatgac aacgattgct gccgctccaa ctaaatacca gacaacttgc
    22321 atccctacgc ctttcaagac tgctggattg ttcggatcat ggctaagtgc tacatataat
    22381 gagagcagac caatcaaaca taacagaaag actggtaaaa tcacgccata atcaatacga
    22441 ttatcgttcg aagcttttaa ttttttttcc atgtttcatc ccttttctta aaaaccatac
    22501 tgctgattat tatagcggtc cagttagata atggaaagtc tttccataga catttgggaa
    22561 aaattaactt tccgtttgtg cagttgcttg agcaaatgca gtacaaaagc ctactgctta
    22621 tctttagtgt atcatagaac tttttttgat acatgcaatt atctaccagc tgagattctc
    22681 ctcgctgtga gaagtttctg tgctttcatt gtatcgaagg atctcttcgg caatctctag
    22741 cagctgatca gaaaccagat tggttcgttg gatgaaataa aaatatcgat ggaaattcaa
    22801 cggagtcatt ggcacatttt ctggaacaga gcgcttagac aaaatcgagc gaccgattcc
    22861 ttccttcagc aacgcaacaa ttacatcgtt acttttcacg atcatcttct tatcttggat
    22921 attcatctct tcaaaataac gctgcgtgta atgaaaaaca ccagagtttg cttctcttac
    22981 aagccacaat ttgctttttg ggtccccagc gatgactagc tggtcttcca tcaaagagta
    23041 tctttgtacg ccggaagtct ctaatggctt ttcgataaaa ccaaaatcgg attcatgttt
    23101 cgctacttgt tctaatgatt catgagaatt cgtgatttcg atctcaaaat gcactttagg
    23161 aaaccttttg atcagatgtt tcatcaactg aggcaaaaga tagacagcaa aggtgtggga
    23221 agcaacgatc cgacatactt cttcttcatt ttgttcattg agcaattttt gctgagtttc
    23281 ttcccattct tctaacaaaa ccagtgtccg ttcatataat aagtcggctt gcttagttgg
    23341 aagcatctct tttcttccgt tacgttgaaa aagatcgata ttcaattccc gctccaactg
    23401 tttgatttga ttcgagactg ctggttgaga taaaaacagt acttctgctg ctctggaaaa
    23461 atttcttgtt tcatatactg ctcgaaaagt cgttaataac ttaaacatgg caccacttcc
    23521 ataacttttt atgataatta ctataaaaac tatttgattt aaatatacaa aaaaccatct
    23581 ataatagaaa tgtacaacaa aacagttgct gatccaacta gtaacttaga tgaagacaat
    23641 cagctgtctg cttgctcgta atcatacatt cctattcatt ttacaatgta ttcgttcatc
    23701 ttggtactaa aatctattaa ataaaaagga gaatattata tatgaagaac tttttgaaaa
    23761 ttattccgat cccgatctgc gggttgatcc ttgggttagc ttcccttgga aatctgttta
    23821 aagactatca ccatgttgct ttaggcaatc taactggcgg tatctctatg attcttatga
    23881 tattcatttt tgttaaattg tttatcttat tcgaacacac gaaacaaacg ttgcatgatc
    23941 caatcatcgc ctccgtttca ccaactttta cgatgtcact catggttatt tgtacttatt
    24001 ttgtttcata tgaaagtatt gcaccaattg tcaaattcat ttggctgtgc gctgttatct
    24061 tccaagtgat ccttgtcttt tatttcaatt atcaccatgt tatcaaagct gatctttcaa
    24121 ttgaagcaat ttatccaagc tggtttatca tttacgttgg atttggggtc atcactgtaa
    24181 ctgccgggaa cttcttccca cttattggaa aaattttctt ttggatttca ttgatctgct
    24241 atgcgttctt attgccgatc atcatcaaac gtgtcttttt cgtaagaaat atggctcatc
    24301 cgacacgtcc gctgattacg atcgttgcag cacctggttc tctttgccta acaggttatc
    24361 ttaaaaactt tgctgaacct aatttttatc ttgtcgtagc attgttcgct ttatctcaag
    24421 tattgtattt cgttgtgctg tctatgcttc cacgtttgtt caagcttcgt ttttatccaa
    24481 gctatgcagc ctttacattc ccgcttgtta tctctgcaac agctatattt actactgttc
    24541 attacttcaa cagtttaggt atctatagta gcgtattgga tttcttaaaa gttgcggaat
    24601 gtctgtttgc aagtgtagtt gtcttctacg ttcttgctca ttacgtacgt ttcttaatta
    24661 aagaacatag caaacatgga aaatttgttt ctaaaaaaat cgcttaataa tcgattcaat
    24721 aggttgtgaa aaagctgttc tgcatcaagt aataagaacg gccaaacaaa aacagctgtt
    24781 catgtttttg tactggttgg gcttattacc gcagatgcaa gcttttgaac accgtttacc
    24841 aagaggtcgt aaaagaagtg gtcagcttca agaaataaga aggaatttac gaaaattgct
    24901 tctcaaattt ttgtgaaatt tcggcttatt tccgtagaag ctacttctgg aacaccgttt
    24961 attcgaaaca agaggtcgta caagactttt gtcacgacct cttgttcttt tgtcaaaata
    25021 ctggtttagt gctactatgt tcgagtatgc ttttagtatt tattgacgaa aggaaccgat
    25081 caaatgaaat cattgtcaca tccaataaaa tctgtaaagg attcagcggt ccgcgaaatc
    25141 ttacccggtt tactgctttc ttttgccatc gctgccttca gcaggcttct tgctatttat
    25201 ctgccacagt taggtggagc gactattgct attttattgg gtattttatt aggaaatact
    25261 ttttttaaac agcctgttct agcaatcggc acaaaatttg ctgaaagcaa actattagaa
    25321 ttctctgttt ttttactagg tgcaactgtc acagctcaaa cgattgctca aattggtgta
    25381 aaaggaattg tttttgtgtt actgcaaatg tcagtcacta tcatcggtgc ttacttgatt
    25441 ggtaaaaaac tgcaattcag cgatacttct tctttgatga tggctggagg aaacgctgtt
    25501 tgtggttctt ctgctattgc ttcaatcgcc ccttccatcc atgcgaaaga ggaagaaaaa
    25561 ggacagatca tcacactagt caatctactg ggtactgtga tgatgttgac tctccctttt
    25621 cttggattac agttgtttgg tggaaatctc attgaaaaaa gtgcactttt gggtggtaca
    25681 ctccaatctg ttggtcaagt agtcgctggg gcaagcttac ttgacaattc tgttgtcgaa
    25741 ttcgccatgc tatttaagat tctacgtatt atgatgctcg ttgttgttgt ctatctgttt
    25801 gaaaaattca tgcacaagaa acaaccagct ctgtttgaaa cgccaactga tacgcagaaa
    25861 aaacgaaaat taccgcttcc ttggtatgta ttagggtttg tgatcttttg tttggtcaac
    25921 agcttgtttt ctttacctgt agttattgac caatcggcac attttatcag cagctggttt
    25981 gagatcactg ctttagcggc aattggtctg cgtttagact ttgcaaaatt catgaaagaa
    26041 ggtacacgct tcttatctta tggattagct gtcgggcttc tccaaacagt gatggcttta
    26101 ctatttattt ggctgatcaa agtttagaat gaacatgaaa aaacagttgt gattctcgca
    26161 tggaacaatg tccgaatcac aactgttttt aattttgcag atatccttct aacaacaaca
    26221 attggcgttt gatttcaacc ccatctattg cgtttcccat atatcctgtc agttttccat
    26281 tttgcccgat cactcgatga caaggaataa cgattggcaa tggattggtt cgatttgcct
    26341 gcccaatcgc tcgcacagct ttcggactat caacagcaac ggctacttct ttatacgttc
    26401 ggatttctcc ataaggaatg gtcgacaaag ctttccagac attttgctga aaaggcgtac
    26461 ctctctttat agataaagga acatcaaatt cttttctttt tcccgcaaaa tattcttcaa
    26521 actgttcttg tgtgcgcgtt aaaattcgct gattcgctga ttcgctttct gaaattggct
    26581 gaaaagatac agcagtcaat ccggattcat ctgcatctaa ccataaaaag ccgataggtg
    26641 tgtgtatttt cattttgttt gctcctagtc aatagactgg aacttcctcc tttttctcta
    26701 tccaaaacta cttgccaact aataaaaatt gttcttaaaa gtttgataaa ccgaggaaac
    26761 atggtaaact aaatacgtta gtttacaaaa agaatacctg ttcttttacg taaaatcaaa
    26821 ttttaaaggt gttatttaag gtttattaaa ttttgaatgt aaaccatata taaacatacg
    26881 attgaaagga tagaaacgat gaaagtatca attgttgtcc catgttttaa tgaagaaaaa
    26941 actgttcctc ttttttttga tgaggttgaa aaattcaaag gtgcccatga gttcgaatat
    27001 ttgtttattg acgacggatc aaaagacggt acgttagcag caatcaagaa gctagcctca
    27061 gcttatcctt atgtccgctt tgtctcattt tccagaaatt ttgggaaaga agcggctctg
    27121 tacgctggat tgcaagcttc tacaggagat ttagtgaccg tgatggatgt tgatctgcaa
    27181 gatccgcccg aactgcttcc tgagatgatc aaccggatca ctacttctga tatcgattgt
    27241 gtcggcaccc ggcgttcgac tcgtgaaggc gagcctgcga tacgcagttt ctttgcgaaa
    27301 aaattctacc agttgatcaa taaaatcagc gatacagaaa tggtcgatgg cgctcgtgat
    27361 ttccgcttga tgactcgtca aatggtggat gccgtcctag aattaacaga atacaaccga
    27421 ttttcaaaag gattatttag ctgggtcgga tttaaaacag aatatatttc ttatgaaaac
    27481 cgcgaacgtg tggctggcga aacatcttgg tccttctgga aattattcaa ctactcgatt
    27541 gatggtatcg tgaacttctc ggatgcaccg ttaacgattg cttcatttat cggcgctttg
    27601 tcttgtgtcg gttctggtat tgcaattttg ttcattattt tgcgggcatt gttgtttggt
    27661 gatcctacat caggatggcc ttccatggtc tcgatcttcc tgttcattgg tggaatccaa
    27721 ttgttatgtc ttggaatcat cgggaaatat attgggaaaa tcttcttaga aacgaaacag
    27781 cgtcctgttt atatcataag agaaacagaa aaagtgaagc caaatgaatt gaagcctcac
    27841 caataatata cgtcaaatga agtaaacatt tttttaaatg aaaaaggact gtgacaaaag
    27901 tcttgtcaca gtcctttttt ccgaataaat ggtgttccag aagtagcttc ttcggaaata
    27961 agccgaaatt tcacaaaaat ttgagaagca attttcgtaa attccttctt atttcttgaa
    28021 gctgaccact tctatcacaa cctctttcat atcttattac ttcttcattg ctgcttttag
    28081 tgctgctgct aatgggcttt cttctggttc ttctgcttgt gcatattttt tcagcaagcg
    28141 tcgttcttca tgtttggtca ttttcttctt ctgctctttt ttatcaagca atttttctgt
    28201 cgttccatcg tatttacaac ggaaataagc accgttttta ccttcgatga tttccatttt
    28261 ccggtgacat tgcgggcatc gatgattaga gacttttgga tcttttcttc tgcggtagtt
    28321 gcaatctgaa ttggtgcaga catagatttt gccgtcacgt gtgtttttct cgcgcagatt
    28381 ggccccacat tctgggcatt tcttttgggt aatcgagaaa tcttgatatt cttgtttgct
    28441 tgatttgatc tcattcacca agcgttttgt ttctttttcg attccattca agaaggttcc
    28501 tgcttgtttc tttcctgcag caatagcttc aaggtctttt tcccagcttt ctgtcaaatc
    28561 tggtgttact aaagagggat ttaccaatac taataattgc ttacctttag gagatacttg
    28621 cagtccttga ggggtacgtt ccatcagttc agatttgatt agtttctcga taatctctgc
    28681 acgcgtagct ggggttccca gactgtattt ttccatttga ccaagcaagc ttgcttctga
    28741 caatggttta ggcggtgcag atagttcttt tttgatggcg aaatcgggat tgattctcat
    28801 tcctttttcc catttgactg tttccgtctc agtttcagtt tcgcctttcc atcctgcttg
    28861 gacgacacga ttttgccgaa aaatgaatcg ttctttacca aattcaaccg taacttttgt
    28921 ttggctgact ttatggggtt gagcaaacag tcctaaaaaa cgagagacaa tcatttgata
    28981 gatttttcgc tcttcattac ttaatttttc ataacgtgct ctgttttcag ttggcaaaag
    29041 tgcatggtga tcggtcactt tactgtcttg gaatactttt gtctgttgga cgatggctcc
    29101 gtttttcaaa tactgcttga cctcaggagc aaagtcgctg actgcttgca atcgttcttt
    29161 catcgtactt ttcatgtcat ttgtcagata tttgctgtct gtacgcggat aagtaacgat
    29221 cttatgggtc tcatacaaac tttgtacaag acttaatgtt ttctttgcag aatagccata
    29281 gcgttgattg gcttctcttt ggatctctgt taaatcataa ggcaatggcg cagattccgt
    29341 ttttaatttt tcttggactt ctgtgacagt tcctttgctt gtactgatca attgaacaag
    29401 tttttgtgct tcttcttgtg tttttaaagc aaattgattt ttttgaagca ttttggcttg
    29461 ttcttttcca gcttgcaacg tgatcgtgaa atacgtttgt ggacggaact gctcgatttt
    29521 cttttcttgg tctctcacta atgctagtgt cggtgtctgc acacggcctg ctgataaatt
    29581 atccgcgtac ttcacagtta aggctctggt cacattcaat cctaccagcc agtccgcttt
    29641 tgcccgggca agagcagatt catacaatgc atcatattct ttcgcaggtc ttagttgctt
    29701 gaatccagtt ttgattgctt tatctgtttg agaagagatc cataaccgct tcactggttt
    29761 attgaaatgc acatactcta agatccagcg agcaacaagt tccccttctc ttccggcatc
    29821 tgtcgcaatg actgcttctg agacatcttt tcgctgagcc agctgcttga ttgcttttaa
    29881 ttgatgtcct gttttaggaa gtggtttgat tcctagtttt ttagggatca ttggcaacgt
    29941 gtccatttgc cagctctgcc attccttatt cagatcttcc ggcattttca atcctaataa
    30001 atgaccaagg gcccaagtaa cgatcacctt gggtccttca taataatttt tgtgcttttg
    30061 attagcacca agcaccttgc ttaggtcttt cgcaacgctt ggtttttccg ctagaattag
    30121 ttgtttcata aaattccttt ctgctttcta ctgtgatggg ctgatgattt ttcaacaacg
    30181 caagtccctt gtattgctgt aaatcatcgt cacactcttc acaccagcgc tcatctccgt
    30241 cattccaaaa ggcgctgaga aagttacttt ttgcattgat atattcataa ttttgatgga
    30301 tttcgttcca ttgtttttcg tacgcttgtc gtgcttcttc gaaagactcg aatgtttctt
    30361 cttcttcaat atcttcttcc cagtcttcaa aaaaccacca aggctcattg tccccgaaca
    30421 tggtaattac ttgatacata ctcgtgctcc ttctttcagc ttttctagac tcatcttagt
    30481 cacttttcaa gaaagttgca agaattttct cttataaaag ggtcatttaa tgaacatctt
    30541 aaaattgtta caaatgaatc tgattgttta aggcaaagta gcgataaagt tattgatcat
    30601 ccaaaaatag ctgtcttctg gatcgattgt tggttctttt gtaaagtatc ctaaaaaacg
    30661 taaggaaaga taaccgtgga tcatactacg aagttccctg cttcgatgaa ctttttcttc
    30721 tttcgttaat tgaaaagcct caaatatctg caaaatgatc tgattcgttt catggattcc
    30781 atctaataaa acagcttcat tggtatgcgg tacactgatc agtaactcat acactgcttg
    30841 atttgaaaaa gcaaaggatc gataagtttc tgcatagatc tgcagtgctt cctgaccact
    30901 ttttcccaca agagcccgtc gcagctggtc attaagttcc tgcagaagtt tcgctgttag
    30961 cgctgttttg acatcacgaa tatttttgaa atggttatac agcgagggag ccttgatatc
    31021 caagcgtttg gctaaatgct gaaaggttat ttgctgaaca tccatctctt ctgctagttc
    31081 tcgaaagcag tcgatgattt tctcttgaga cagatttctt tttttcattt ccatgtttcc
    31141 tctcataaaa taaatccttc actctttcag tttaccacga aaaagaaaga gaaaaaagag
    31201 actttcattg ataaactaca tattgtagtt tataataaag agctgtagat gaaaattttc
    31261 agaaagaagg agtctaattg gctgcaagaa taaaggaaaa attatttagg aaaagagaaa
    31321 cttgggaaca aaacttgttt gtcttatggt ttggaacatt tatggctggt atcggattta
    31381 gtttagtcat gccttttatg tcactttaca tagatacgtt aggtaattat agtacgtcac
    31441 aattgaactt ttggagcgga ttgacttttt catctacttt cttggtgact acgcttatct
    31501 ctccttggtg gggaaaatta gccgaccaaa aaggaagaaa attgatgctg ttgcgtgctt
    31561 cattaggaat ggcaatcgtc atttctttga tgggttgcgt gactagtgtg tatcaattag
    31621 tcgcattgcg tctgcttcaa gggatttttt ctggttatat cagtaatgcc actgcccttg
    31681 tcgcaactgg gacgccaaaa gaaaaaagtg gtcaagttct tggaacctta gcaactggtt
    31741 ctgttacagg aacattactt ggaccgcttc ttggcgggat ctctgcttca gcgtttggct
    31801 atcgccctac ctttttcatt acagggatca tcttattttt cgtcttcttg ttgagtctgt
    31861 ttttcgtcca tgaaaaattt gtcccagtga aaaaagaaaa catggtttct gccaaacaga
    31921 ttttcaaaga cttgaaatat ccacacgtcg tcatcggtat gttcgtcaca acgatgatca
    31981 tccaagcatc caacaattcc attagtccaa tcatcagtct gtacattcgc caattgctgc
    32041 atggacatgg gaatgttacg ttgatcagcg gaatcattgc ttcgatacct gggattgcca
    32101 ctttgatagc cgctccaaga tttggtcgct taggtgacaa gattgggagt gaaagaatac
    32161 ttgcgattgg tttgggtttt gcgattctgg tttatatccc aatggcattc gtcacgaatg
    32221 tttggcaatt agctgcctta cgttttttga ttggtatctc tgatgcttgt ctgctccctg
    32281 ctgtccaagc attgatcaca aaatattcgc ctcatcaagc tgctggacgg atcttcagtt
    32341 ataaccaatc tttccaagca actggtaacg tagtagggcc tatgatcggc tccagtgttt
    32401 ccagtgcatt tggttatcgc ggcgtctttc tttcgacttc tcttcttgtt ttggtcaact
    32461 tcttgcttgt acgacacaat acacaagaga tccatcagca agaaactgca gaagaaaaag
    32521 cttcaggagt ctccatagct tcagggcact ctccttctca tagacaataa gcgtaaatga
    32581 aaaacactgc ttgaacagtt gtcacagact gtccttgcag tgtttttgtt taggcctgtt
    32641 ttttcaagaa ctcagataag aggaataatc ccttttccaa ggtttctttt ttacaacagt
    32701 aacctagtcg ggcatgcttc ggtaaatcaa aggcacttcc tggtactaat agtactcctg
    32761 tttcttctaa taaattgata caaaatgtct ggtcatcttc ttcgatggct aatttaatga
    32821 aagaagtaga gacgtaattg ggagcgacaa gttcaacttt cggttcattg gctacccatt
    32881 gttttaaaat cacaaggttc tctgtaatga tctttttgtt tcgcgccaat attttttctt
    32941 tattcttcaa tgcatgtaca gcaagatcat ctgacaggac tccgccgcaa atcatcgtgt
    33001 agtctcgata ctttcgaaaa acttctgcca actcaggtcc agtagctgtc cagccaatac
    33061 gaatacctgg aatggagtag gttttggata gggaattggt tgctatacct ttttcataga
    33121 catctacgat cgacaagaat tcacctttat ccgttaaagg cgcatatact tcatctatca
    33181 atacatatgc atctactgta cgagcaattt ctgcgatttt ttctaaagtt ttccgatcta
    33241 gcaatgtgcc tgtaggattg tttgcactat tcaaacagat gatttttgtt tcaggtttga
    33301 ctaaggcttc tagctgttct aaatcaaact gccaatcttc ttcttccttc aaatgaacaa
    33361 agtcaacagc ggcacctaaa gatttgggga tgtcatataa ttgctgataa gtaggaagca
    33421 tcgaaacaac atggtctcct gcttccacta acgcgtatag agctaaaaga ttagcaccag
    33481 tcgctccatt cgtttgtaag atgttttccg gatcgacggt ttgataaaga gaagcgactt
    33541 cttgtttgaa aacatctgat ccttcgatcc agccatagtc caatggttcg tttttgcgtt
    33601 tttcgaaaaa tttacttacg ctagtcccat ctaagccaac gagttcgtct aatgtcaatg
    33661 cttcgatcga gctttgtgca atatcatata ccgctttctt ttcccattta tttagccatt
    33721 cttctacacc gaaatttgcg attttcatgt ttctttcccc cttatatctt gatccagcct
    33781 acagcaagca acccgattga aagcagtgcg gccacacaaa tcagcccaat cattactttt
    33841 tcttttcccg taatttgatg tttggtttca cgacaagcga tccagtagaa gcaaaaacca
    33901 ggaagatagg caatactaca taaaaggaca taagaaaatc ctgctaaaat gatgcccatc
    33961 aattcaaaaa ctacagcaat cccaccgatc actacttgtt ttttgattcc ttcttttaaa
    34021 gaaaactgga cttgatagat cccgacaagt agataacaaa tcaaaattgc cgctgtacat
    34081 aaagaatagg caaattgata ggcataatca gtaactaaga aagtcaataa gaatagatta
    34141 gtcaagattg cagtaacaac taacgaataa gttggggcat tttttttatt cgtttttccc
    34201 caacctttcg gcaacagacc gtctcgagcc atcaacatcg ttgtttctgc tgggagcatc
    34261 gtccaagaca accaagaacc aatgatcgaa ataatcaagc cgatattgat cagcgctgct
    34321 ccccaatttc ccacgattcc ttttaaaata tttgccatag caggttgtga aatagttgct
    34381 aactcttctt gagataagac gccgtatggc aagatcgaag caaggatata gataaacaat
    34441 aaacaaagca gaccaatgat cgatgcttgc tgggcttctg aacgtttctt cgcgcggttg
    34501 gctaaaacac ttgcgccttc gatccctaca aagacccaca tcataaccat caaacaacct
    34561 ttaatctgca accagatcgt tccttgctgc cctgttccat tcactagatt atcagatacg
    34621 ttaccccaaa aatcagcagt gaatatattc actttaaatg cgataaatac aaatattaaa
    34681 aataggaata atggcactaa tttacagatc gtcacgattg tattgatgac gctcgctcct
    34741 tcaactccat tgtttactaa taaagtcaga ccccaaataa aaatacttgc aaataaaata
    34801 gaaggaacat tttgtccacc tttgaatatc gggaaaaatt ctcccatggc gctcatcagc
    34861 atcgttgcaa aagcaacatt tcccagccac gcagacaacc agtaacccca accactgatg
    34921 aagccaccta atttaccaaa tgaagcttcc gcgtaaccga aaataccacc atctagatct
    34981 ggacgctttt ctcctaaatg attcagcgat aataccaaag ctaaaatacc aatcccaacg
    35041 attatccatg aaaggatcgc tggccctgga gctgcagaac tagccagatc acttgtgatc
    35101 ccaaacacac cgcttccgat tgacgaactg acaaccagag caaccagtcc ccatttgcta
    35161 atacccgtcg atttcttttc catttccatc accctcactt ataaaattga acaaatcact
    35221 tgcaaaagat tcccttctat tttgcaactg ctcttgctta acaaaaagca actttattca
    35281 tattattgga tattatgaac tttttacaca agtatttcaa gtataaaatg aataaaaatt
    35341 aattttattg caaaaaaaca gctatgctat ccaaaagaaa aggtgtttct tttgttagcc
    35401 atagctgttt tgattcattt aatatcgctt aaacgtattg taaaactttt gtttcttgat
    35461 atgcgtggtc gatcaaacca ccacccagac attccattcc atcataaaat acaactgctt
    35521 gtccaggagt gattgcacgt acaggttcgt cgaatacgac ttctgcacga ttatcatcca
    35581 ataagcgaac tgtcacagga acgtcttgct gacgataacg gaatttcgct gtacacttga
    35641 attcttttgg cattggttca ttcgtcgtaa agtggatttc acttgcatcc aagcttgtgg
    35701 catacaatgc aggatgatgg aacccttgcc ccacatataa tgtgtttgtc gctagatctt
    35761 ttcctacaac aaaccagggt tcttgcgaat ctcctccgcc accgatccct agtccttgac
    35821 gttgaccaat cgtataatac atcaagccag catgttgtcc tttgacttca ccatcaagag
    35881 tgaccatatt tccttttttt gctggcagat agttgctcaa aaattgtttg aagttctttt
    35941 caccaataaa gcagattccc gttgaatctt ttttcttagc agtcgcaagg cctgcgcgtt
    36001 cagcaattgc ccgtacttct gatttttcca tgccgcctag agggaacatc gtttttgaaa
    36061 gctgttcttg tgataattgg ctaaggaagt aagtttgatc tttattattg tctactccac
    36121 gaagcatgtg gaccacgccg ttttcatcgc gagtgacttg cgcataatgt ccagtagcta
    36181 cataatcggc gccaagatcc attgcataat ccaagaatgc tttgaatttg atttctttgt
    36241 tgcacatcac gtctgggtta ggtgtacgtc ctgcgcggta ttcggctagg aaatattcaa
    36301 atacacgatc ccaatattct ttttcaaaat tcacagagta ataaggaatc ccgatttgag
    36361 cagctacttt cgctacatcc ttataatctt ccgtggccgt gcatacaccg ttttcgtccg
    36421 tgtcatccca atttttcatg aatattccga tcacgtcgta tccttgttcc tttaacaaaa
    36481 gtgctgttac agatgagtcg acaccgccgc tcatccctac gacaacgcgt gttttgctgt
    36541 tgtctgtcat gatatcacca tcatttcaat tagattctga aacatctacg agttgaaggt
    36601 cgcaactttt cagtatttta cattatacgt catatttctg aaaatttcat cccttaatta
    36661 tcaagtcgta aaaatactgt tctactggac ctattcagta cacaaacatg atagtcaacc
    36721 aaaaaatcac tcatcttttg agcattcgat ataaaaaatt ggcatactca taaaaagggc
    36781 cagcctttcg gcaataagga ataattttat aaattgtgaa aaactatttt tcaaaattgc
    36841 ttcttatcgc ttaaagctgc acgtctcatt tacaaccttt tctttttaga tgttatgagt
    36901 tgctcagata agtgattttg tttactctaa gaaaaaaggg aggcaaaaga tacatgaatt
    36961 actttatcag tgatatgcac tttttccatg aacgcttatt aggaaaaaac gactttgctc
    37021 cgcggctctt tgcaaatgtg gatgaaatga accaacagtt gatcactagc tggaatgcag
    37081 taataaaaga aaccgaccat gtttatcatc taggcgacct tgctatgcat ccgcaatatg
    37141 aaaaagcaaa tgcagaaatt ttggaactgg tcactcaact gcaaggaaca atccacttga
    37201 tcaaagggaa ccatgacagt cgcgcttttt tccgttattt agaaaaaaat gatcctaggc
    37261 ttactgacgg aagtcccaaa ttttattttt atgatgtagg tgccatcgtt aaattcgacc
    37321 atcaacaata ttacttgact cattatccga tgttgctcgg gcctaacgac actatccgca
    37381 atcttcatgg acatatccat cattacagcg tacctatcga gaacgatgtc aatgtaggcg
    37441 tagacgcacc ggaaagagaa ctcttaaagg aaaaactacc atttggcact ccgttatctg
    37501 agcaacaaat caaagaaatc tatgaagcaa agaggaagta cgataggtcg tgaaaaaact
    37561 gccctatatc aagtattaaa caaataaaga taattactca tatttttcat ttgagtaggc
    37621 ttattgccac aggaacatta ggatcagaaa tggagttgta acaagacttc tgtcacaact
    37681 ccattccata ctattcgtct ttttgctcat ggtgttcttt taccagtttt ttctgtaatt
    37741 ctttatcata atttcgggca gctgacgtta aaaataaaac gattccgcat aataaaatcc
    37801 cgattccgga aaacaagaac attttttcta cccctaaacg atcagctaat ggtcctgcaa
    37861 ataataatcc aattggacct gccaggttca tcaaagagtt gaagttccct aagacacgac
    37921 ctaaaacatt cgattcataa ctctgctgga tcattgccat cagcagtgta ttgaaatatg
    37981 gcgttgcaca acctgctcct gcattcaaga taagaaagta caagaaccct tgactatcgt
    38041 ttggaaccaa tccgcttgca ccgatcgtca ggcccataat gatgtaggct ataataatag
    38101 gtttcattcg gtctttccat gttcctataa aactgatcag tgcaccgcct aagagcattc
    38161 cgactgcgta gactacttcc actgctcccg cctgtccaac ggaaccacca aagtaatcta
    38221 gcgtcatcaa tggatacaga ctgattgctg gcatgaacaa cagcatcaca aatgcaccat
    38281 tgatcgttat gtaccataac cctttattat ccatcaattg ctgcagccca aattttgcat
    38341 ctttaaaaat agtaagcgga acttccaata tttcaggaga aacttttggg atcttcacaa
    38401 aaatcaataa gccgacacca aaaactgccc ccaatacatc taataaaata aggtaattga
    38461 caggaacgac tgaaaacaaa gccgcaccta gagctggcgc aatgatgaaa ttcgctgatt
    38521 ggaccattcc taactgtcca ttcgtccttg ttatgtgaga agatggaacg attgtcggca
    38581 taatcgactg gatcgttggc atttggaatg tttgtgcgac cgaacgcata aacaaagaca
    38641 caaaaactag ccaaatcggg aaggattctg aaatcgttcc gactactgct aaaataagcg
    38701 cgaaaatcgc tacaataata tccgtgacaa tcaaaagagc ttttttatcc cagcgatcca
    38761 ctagcggtcc tacaaatggg cttagtaaaa ccatgggaat cattcctagt aaagtagcaa
    38821 aactcaaaat tgtcgccgaa ccggtttctc ttgtcaaata ccagatgatc gcatattgga
    38881 cgaccatact agtgattcct gacaaaaact gtcccgataa aaagaacaaa taatttctct
    38941 tccaattcgt taaaacgacc gactgttcat tttccataaa catccctctt ttctttttca
    39001 ttttgtatag cgtttgcaca acaatcatta tacgggattc ttttttcaaa aaataccttt
    39061 ttccctaaat aacaatcgtt tcaatttaaa tttctttact tagaaacaat aaatcagcaa
    39121 aatattaaaa ataacaacat gtgttaaatt taaaaataaa aaagacaact aatttgcgtc
    39181 gtccttacaa agttagtcat ctaacaatag gccgtttcaa aactagttgt ctttttatat
    39241 ccacagatca ttcgactttt tcgaataacc cacggctaat catcccatcc atcagaaaat
    39301 aaaatttatc ttggctcatt ttctgttttg gatctttgaa aatattgact gctttcaatc
    39361 catttgctgt agtgatcgac attttcaatg tttgaatatc ttttgataca gtgattttta
    39421 atttgaatcc ttctttgctt tgcggcgtgg catctaatgg tcggatcaat tgataattgc
    39481 ctccgtttgt ttctgtaaat ccattatcgc gcaatgtata tctttttgca tcaggatgca
    39541 aacgatagct aattggtgcg cccagtaccg ttgctgttgt ttcaaatgcc atgattttca
    39601 cctcgataaa attagtttct ctttattata aaagtttatc ctgattttta ctaggttttt
    39661 cagttaagtt ccctaaaaaa tgaaggcgtt ctctcagaca tctgttcata taagaatgac
    39721 ttcactagtt attttttgac agcacgaact aattgatcaa ggaaatactg gatgtcgtct
    39781 tcggtatttc ccaaaccaaa gctgatacgg atggattctt ttagtatcgg tgtatcttct
    39841 ccatacattg cttctaatac gtgtgaaggc tcgatatttc ctgctgtaca agctgaacca
    39901 gtagaaatag cgaccccatt aagatcaagc ttcatcagta gcaaatcatt tgcttcgcca
    39961 attaagcgaa gattcaacac atgagggagt ttattcgtta aatcaccatt tacttgataa
    40021 gggatttcgt ttgcttctaa tgtatcaaga atcaattgct ggaatccttt atatttgttg
    40081 ttacgtgctt cacgttcttc aggtgacagc agttcaactg cttttgccat accccagatc
    40141 cctgctaaat tttctgtacc tgcacgccgc ttttcttcct gctccccgcc taaaagcaat
    40201 gcagggatat ttactccgtc tcgtttatat aagaaaccga cgccttttgg cccattgatt
    40261 ttatgagcag agatacttaa taaatcgatt cctaattctt ctggatggat cgtttggttt
    40321 ccgtacgctt gtaccgcatc tgtatggaaa taagctggat gatccgctaa aagttcaccg
    40381 atttctttga ttggcatcaa atttccgatt tcattgttcc cgtacatcac agagaccaag
    40441 atcgtatctt ctcgtaacgc ttttttgacc tcttcgatcg acagattccc tttttcatct
    40501 acaggcagat atgtaacgtc aaaccccttt gtctctaaat atttcatggt attaagaaca
    40561 gcaggatgtt cgatagctgt agtgattaga tgtctgcctt ctttttgacg cgagaacgct
    40621 gtttctaaga tagctgtatt atccccttct gttcccccac tgttaaagat gatctcgtga
    40681 ggttttgctt gcagactgtc tgcaatgatt tgtcttgctg tttccaattt ttcatgcgcg
    40741 tggcgaccaa atccatgtat gcttgaagga tttccaaacg tgtcttgcat gattgccgtc
    40801 atcgcttcaa ttacttgtgg atgcatgggg gtagttgccg catgatccag ataaatagtt
    40861 ttcacttcat tcatcccttc caaattattg ctaggcacat tctagcataa aatagcgaac
    40921 aaaccaaaga agagctcatt tttgtctaga ggacgtttca tgggcataga aaaaaggagc
    40981 tgtgacaaaa gtcttgtcgc agctccttga agctgctcac ttctgtcaca acttctttcc
    41041 ctcttttttt tgtttattcg aattcttttt cttccagacg gaataacgga ctcatcggtg
    41101 tattttcatg gatgcgtttg accgcttcac ccattaattc tgaacatgta acgattgtta
    41161 agttttctgg atgacgattt tcttctgtga aaacagaatc agtgatacaa atatctttga
    41221 ttggtgcatt gtctaaaata cttttcgcat gatcggacaa taatccatgt gacgcacagg
    41281 catatacttc ttttgcgccg ttttctttta atacatttgc tgctcgtgca agcgttgctc
    41341 ctgtgttcaa gatatcatct accatgatac atgtctttcc ttgaacatca ccgatcacat
    41401 aaccaccctc agttgaagca tcatctgcat gatctacgat ggctaatgtg ctgttcaaat
    41461 attctgaaag actacgtgca cgctgaacac cgctgttttt tggcgaaaca actacgatgt
    41521 catctcccgt cagacctaat tgacggtaat aatgagcaaa caacggcatc gtaaataaat
    41581 tatctacagg aatatcaaag aatccttgta cttgaaccgt gtgcagatct aaagtcagta
    41641 ctcgagttgc ccctgcttct tcgatcaagt tagcgatcaa tttcgcagtg atcggttcat
    41701 gaggtttcgc cgtgcggtct tgcctagcat acccatagta aggcaatacg acattgatcg
    41761 ttttcgcact tgctcgcttc attgcatcga tcatgatcag tagttccata tagtaatcat
    41821 tgacaggtgc attcgttgat tgaacgatat acacatgatc ccctcgaata ctttcttcga
    41881 tattgatgga aatctcgcca tcactaaatt gcttcacgac gcttttacct aattctgttc
    41941 cgaacacttt cgcgattttt tcagctaatg gacggttgcc attcaaacta aaaatcttca
    42001 acgtgtcatc ctgatactta ttactcatgt agtcctcccc aaaacttctc tattcttcga
    42061 tagtttaaca tatttttcca agattttctg ttaatttcag caaattctta aggaagtgaa
    42121 actgttccgt tactccaact ggcaggaatg actttatgat aatcgcccca gttgtcgtgt
    42181 actttgtaat aacgttctcc tgtttcagtt tcaaaataag cgtacgctgt cacccaatga
    42241 ttgccatatg tactgccaag tactttcaaa ataccaatca tcacaggttt gccttcacgt
    42301 atacgttttg tagctcgctg ccatgaacct agaagagttg ctcgtgcacg ctcatgattg
    42361 ccattcttct ttaaaaaact agaaatccct gtactaacct gaaaaggaat cgtaggaagt
    42421 cctagtggtt ggatctggct acgcaatgcc ttcgtcaaaa ccaacgaatc agccgtattt
    42481 ttcttgcgaa tctcatttgg aagcatccac cccttacgat agtcttgata ataggcaagg
    42541 agaactgctg ccgcgtaagt accacaaaga tagcctgagg gggtagccca tttcttatac
    42601 ctcaaaaaac gttcttctgg caatcccacc cagcaatttg cgagttcctt tcctgacctt
    42661 ttttcttcga tcaaaacggg aatatcttct tttctgttga tccatctaga taactcgatt
    42721 ggctcttcat tgatcagctt ccatttttta caagaaagac cctcttgata agtatatttt
    42781 gctggagaat attctaccgg atgtcctgat tgatcgataa tcacataact ttgatcttca
    42841 aaaaccagag ctaaaaaaag caatttactt tttcttgact gcagctgctg agtgctggct
    42901 aattttttaa tttttttatc tactttgaaa tataaaggtt tatccactac ttgattcagt
    42961 tgggatcgcc tccttttttt cattataagt gaaggattga aaaaaacaaa tcagtttgat
    43021 tgttcgaatt ttcaattttt tatgttctat ttgttaattc cttcattttg taagataatg
    43081 ggcacacgaa acaaaaaagg agcgatcgat gaatgaacaa agaacgattg aaacaagatt
    43141 tctatgaagc agtcaatgaa gaatggcaaa aaacagcaaa aatccctgca gataaaccag
    43201 ctacaggcgg tttccaagat ttagttgacg ggatcgacca acttttgatg ggagaaacag
    43261 acgatctgct tgcccatcca gaaaaagtgt cttcagaaaa aatgaaacat ttccttgcat
    43321 attatcaact ggcaaacgat tatgaccgaa gaaatgagtt gcatgctcaa ccgcttcaac
    43381 ctataatcga aaaagttgaa tcattgcagt ctttcgacga attgaataag caatttccag
    43441 aatggctgtt ggatacatta ccattgccat ttaatctgga tgtagatgca gatatgaaga
    43501 atgcgcaaac gaacgccttc tttgcttatc cgccttcttt attccttcca gataagacgt
    43561 attatgcatc agaccatccc aacggtgcac aactaatagg cgttttcttt gatatggctg
    43621 ttcagttatt agagcttgcc ggcaaagaaa aaagtcaggc agaagcaatc acggaacaag
    43681 cagtgcaatt tgataaattg attgctcctc atgtaaaaag tgcagaagaa aacgcagatt
    43741 acagcaaaat gtataatccg caatcttttg atacatttat taaatacaca gataaactgg
    43801 acttgaaaaa acttgtcacg ggtttgattg ggacaactcc agataaagtg atcgtaactg
    43861 atccagtgta cttcgatcat ttgaatgaca tcctgacaga agctcatttt ccgttattca
    43921 aaagctggat gatcattaaa acagtacgtt ctcttagtgg ttatctatca gaagaattcc
    43981 gccaagtcag cggaatctat tctcgcgtat tgtctggaac agacgaagca atgcctcaga
    44041 aaaaagcagc gtattacctt gcctctggac aattcgatca agtagttggc gattactacg
    44101 gaaaaaaata ttttggcgaa gctgctaaaa aagacgtaga acaaatggtg aaaaaaatga
    44161 tcgccgttta taaaaaacgt ctagaagaaa atgactggct tggggatgca acaaaagaaa
    44221 aagccgtcat aaaattaaat aacttaggta tccaagtagg ctaccccgat aagatcccag
    44281 cattattcga ccagttcaaa acagtacctg cagatcaggg tggtactttg ctttcaaata
    44341 ctcttgtttt cagcaaactc acattaaaag atcgtttcag caaatggaac aaaccagtgg
    44401 atcgttcaga atgggaaatg agtgctgaca cggtcaatgc ttattatcat ccatttcgga
    44461 atgtgatcgt ctttccggca gcgatccttc aagcaccatt ttacagtcta gaacaatcaa
    44521 gctctgctaa ttatggtgga atcggagctg ttatcgctca tgagatttcc catgcatttg
    44581 ataataacgg cgctttattt gacgaatatg gcaacttgaa caactggtgg acagaagaag
    44641 atcttacaca atttcaaaac aaagcacaag caatgatcga agaattcgat ggtctgcctt
    44701 ttgctgacgg aaaagtaaac ggaaaattaa ccgtttcgga aaatattgct gatgcaggcg
    44761 gtctaagctg tgcattggaa gcagcaaaaa cggaatcaga tctttctatc gaggaattct
    44821 ttgtcaattg ggcaacgatt tggcgtacaa aagcaaaaaa agaataccaa caacttttac
    44881 tgcaaatcga tgtccatgcc cctgctaaac tccgagcaaa cgtgcaacca aaaaaccttg
    44941 acgaattcta tgaaacattt ggtatcacgg aacaagacgc tatgtatcta gcgccagaaa
    45001 aaagagtgcg aatctggtaa gaggttgtgc cagaagtggt cagcttcaag aaataagaag
    45061 gaatttggga aaatcgcttc tcaaattttt gtgacatttc ggcttatttt tcgaagaagt
    45121 tacttctgga ataccatgta ttagaggttg tgaaaaagct gcttagtttc aagtagtaag
    45181 aaaaattttg tgaaaatggc tttccacatt tttgcataaa tttgacttac taccgagaaa
    45241 ctggcttttg aacaccgttt atcgagaggt tgtgaaatca gcgtcctgac ctgagtatta
    45301 gagaaaaaaa cggaaaaata gttcctcata ttttgccgtt tgttgagcta ataccgaggg
    45361 tcagctgatt gaacaccgtt tagtggagag attgtgaaaa agctgtcctg catcaagtaa
    45421 taagaacagc caatcaaaag cagcaaggag aacctcatct ataaaaagat agaaggaagt
    45481 gagacatcta ttggtctcat ttccttctat ttttactttc ctcagtcaat tgttttacat
    45541 cataaaagga gaaattccac ttattttttt cgctgtttca tgacataaac aactacaccg
    45601 attaacaaaa ttcctccagc taatgctagc aacgggttat taaattctcc cgtttttggg
    45661 agtccttgag tgccattttt ttcactttct tttgctgtcc tatccggatg agaaggtttt
    45721 ccatttggtt ttccatttgg tgattcattt cctggatttt ctctttctgg tttgtcattt
    45781 cccgggggca catcggcagt ttctcgcaca gtgatcgctt tttgctgggt aacagattct
    45841 gtatgagcag accatttttc cccatcaaat atttccgaac gataagtgac ttctagcgta
    45901 tattctcctt ttgaaggtgc tgaaaaaata gcggtatgat tagaaaattg agcacttgac
    45961 tgtgtttcaa cgatttggat cttttctggg aaataacgca tatcttcaaa gacaggcgtt
    46021 ccttgatttg gtgtgaaagt tgacacaaaa actgtaaaag gcttcagttc aatgatattt
    46081 ccttctgcat tctccgccac accatttgct tcttgtataa taatcggatt attttgttca
    46141 tttggttttg tctgatttgg ttcttgtacg attgcatact ctggatattc cgaagacggt
    46201 gaggtttctc cgtcaaaaat agcacctaca gataatggaa gaccatccac tctttccttt
    46261 tctgtttgac gattccccgg tttaatctgc atcagtccat gaacatggat acttccattt
    46321 tcatagcgcg taacaggctg ctgaccttct ttcgaacatg tatttagaga ctcgatccaa
    46381 tcttttgata tggtatgtcc aagagtattt tctgattgtt tctctcgttc attccaatag
    46441 tagttcaacg agtggtagat ttgatcttcg ttttgattca atgggcggat ctgctctctc
    46501 atctcaagat tctctgttcg gaaagataag ataccagaag catggtagtc tgtgtttcct
    46561 gctgaagagg tataaagagc cacattatat gaaccgttat taaaacttgt actgctattg
    46621 acgataatat ctgttccgct attggaatcg attcctttcg caagattttc gaaagacaaa
    46681 ctattgatca attcatgagg gcccgttaaa gaagaaccgc ccattttgaa tccattaccg
    46741 ttaccttctc cctcaattcc tggtacccag ccgtttcgat aagcaactga gtttttgatg
    46801 attacttttc cgatcgaacc tgtttcattt ttagcaaaaa ggtcccaacc gtcatctgca
    46861 ttatgatacg cgatacaacc gtcaaataca tttccttctc ctattgtcag tttggccgca
    46921 aatccatcgg catcttcaaa tcctggatcg gcattttcaa aagatgtaca gttcttgact
    46981 aagttatgcg cgggccatgc ttcgaaagga tcatttgagc taccgctgat ttggattcct
    47041 gtatttccat tccgataagc atgaatctct tcgatcaaat tatgatttcc agaaatctgt
    47101 aatccttttt gcatagctgc actatttgta atgtcaaacc ctcgtaaacc ccagtagtga
    47161 ctgaacagtg tcatcccatt tccagttcct ttaaaatcaa gtacaggacg cttgttttct
    47221 ggatttttct ctgcaatcaa ctgaatcggg ttttctcttg tcccgttaac gccttttgga
    47281 atcgtcaatc ctctttcgaa ggaataagtt ccaggcgcca tgacgattgt ctgcccagca
    47341 tatgcgtatc tcaatgcttg tgtcagagat aatggatttt gtctgcttcc gtttcctgca
    47401 tctgaccctt ctggtgttac ataaactgtc gaatatttag gtttacggta gtccactgta
    47461 tgaagaatct cttttgtttc ataactagtc atctctacgt attcttctgg cggatagttt
    47521 ttatctggcg taaaactgaa agtaaattcg ttcgttcctt ccatcagttt tgtctgataa
    47581 tcaaattccc gattcgcagt gatagccaag ttttttgcgt tcttaagcac ctctcctgtt
    47641 gctttatttt taattgtcaa taatccgtca gcatttgctc taaaggacat agtatgatct
    47701 tggtttcctg aatgattact agaggtcaca gtgtaaatcg gatcaatcaa gcgagtaggt
    47761 ctttcttgcc caggaggatc tgtcgcagga tctgagtaag caacttcgat tccttctacc
    47821 ttgatcgtca tattccttgc tgcagcaaat cctgcataaa taaccgattc atctgaagcg
    47881 tataattttt cccagtcata catgatgtca gaagccattt cttctcctgt ttcaggatcg
    47941 taataatatg cctctaaacc agtattcgtt tttttcatct ctacgtccag tttagtaatc
    48001 gagttcgtgg ccggaaacag attcccatga ccgtttccga atatattata agaacctgtt
    48061 tctttttcca agaaccctgc tgaagtctct aaaggtgttg tttccactga gacactccca
    48121 ggagctggcg cagcttgcgg atcttcagat gatattcctg tgattgcccg tgtccccaat
    48181 ccaagtcgca tcgtatattt gctgccgctc gtgttgacca cttcttgtct atccgagtcc
    48241 cagacatatt cgatccgact gcctagtatg gcaaatgaat ttgaataaaa tgcctgccca
    48301 aacaaatgat tttttggtac tgcgtctctt accattaaag caaatccttc ttgggcattc
    48361 gtataggtcc aagattctat ttcgatcgtc gcccgcatcc taaagttgat gtctttgggg
    48421 attgcttgat aataataggt cattccatct gatccgcttg actggaattt tccgccgtta
    48481 ttcgtggaag agagccgcac gccgtcttct aatggttcaa tggcatacct actagcactt
    48541 gtgctttctc cgaaaacaac ccctttccac tcttcatttg cttcttcaga ttgctttttt
    48601 gtcttttcat tttctgattc tttcatcata ggatcatttc cttcttccgt atccatatct
    48661 tcactagttc ttggtatttc ctccattgtt gacatccctt caatgttcac gtgtgcattt
    48721 tcttcgttca cagactgttg ttcgttagca gcaacttcaa cgacagaaat taaaaccggg
    48781 gtactgagca taaggagatt catcattagc gcactgtatt ttatacgttt ttttaacaag
    48841 tgtattcctc ccgtaacaaa ttagaaagcg tttacttaaa gtattaccta atttattttt
    48901 actgtcaata aaaaacaaaa ttataataag tgtattttat aaaaagaaaa aatataactt
    48961 aagttgttga taataaagag atttattaac gtaaaaagaa taagtttttt taaaataacg
    49021 tataaaaaag agcataaaac aaagtcgttt gttttatgct cttcttttat tattttgtgc
    49081 tttttatttt atcaaatcac tttgtttttt tataaaattt ctgcgcctag tgtggactca
    49141 aaatgtctca atgcccattc atgtccaacg ggatcgaaac ttgccacgga atctttgaaa
    49201 atatggagtt tgtatcctag attatacgca tcgactgctg tatgcaacac acagatatct
    49261 gtacatacgc cggtcaaata aatatctgtg atctggcgtt ctcgcaaacg gatgtctaga
    49321 tctgttccac taaaagcgga ataatgccgt ttgtctatcc aataaacatt ttcctcttgc
    49381 tcatagtctt ggtataaact ttttaaagag ccgtacaatt cccgtccacc cgttcctatc
    49441 acattatgcg gaggaaataa gcggttctcc ggatgaaagg aatcttttgg atcatgcgca
    49501 tcaatggcaa aaacgacaaa atccttttga tcaataaact tctttgtatg agcagtcagc
    49561 tttttttcaa ttacttgtcc tgctgtccca gtagtcagct ttccatcctc tgcaacaaaa
    49621 tcatatgtgt agtcaatcga gatcaatgcg ttcatcttag tcctccttat acgagatgtt
    49681 tgacaaattc gatcaccatt tctgctgatc gtttgcctgc gtcttcgata aattcgtcaa
    49741 agctttgtgt cgccgagtga tctgctgtgt cgctcattgc acgtacgatc aaaaatggga
    49801 tattgaactg acgagctgtt tgtccaacag cggctccttc catttcgcaa gctaatgctt
    49861 cagggaaatt cgttaagatt tctttgattt tatctggcga gtcgacaaat gtatcacctg
    49921 taacgatcaa tccttctttt gcgttcaaat tcgttgcttt tgctgcttta accatttcac
    49981 tgcgcaaata tgtgcttgct tcataatata gaggcattcc tggtaattgt cctgggttgt
    50041 agccaaatcc tgttgcatct gcatcaaaat aagctacttt gtctgatata acgatgtcac
    50101 ctacttgtaa gccttcaccg attccgccag ctgaacctgt attgatcacc atgttcacgc
    50161 cgtattgttg gatcaacaga cttgtggtaa tagatgctaa gacttttcct ataccggaac
    50221 gtacgacgat cacttcgtgg ttacctaatg aacctgaaat aaataaagcg cctgcgcgtt
    50281 cccatgataa tggttcgctt aggttctctc tcaaaatttt tacttcttct tccattgcgc
    50341 cgataatacc gattttcatc tttttaattc cttctttcta tataaatgcg attgctaaaa
    50401 aaaccacaca taacattagg ataacaataa taagagattt catcaaaaaa gagttccatt
    50461 tggtcgtctt ttcccgttcg ctgatccttg ttttcgtgat tggtttattc tttttgcttt
    50521 ctttacgata aaagctggca atcttttttt cttcttgctg ataagctgtt tctgcttttc
    50581 gctgtttttt taatgactcg cttgcttgtg cttgttgtcg cttgcgaagt tcgcttcgcg
    50641 taataagcgg tcctttggcc ataagccgat ccctctactt tcctttggtc aatagttccc
    50701 agtattgaat cgcataaatc gtctttgcat cacaaatcaa ctgatctttc atcgcttgtt
    50761 gcgcctcttc aagagttaga tgatacaact ccagtacttc gtcttcatct tgtgctaaag
    50821 gattctcgac cttctctacc ccttgtgcat gataaatatg aaggacttca tttgcaaaac
    50881 ctggtgaaag atacatcgaa gtaagatggc tcagcgactt cgcacgatag ccagtttctt
    50941 cttctaattc tctagctgct gtcatttcgg gattttgtcc ttctcctgga tcgatttttc
    51001 cagctggaat ctccaaaatc actttttcta aaggttttcg aaattgtttg acaagaagca
    51061 gacgatcttg ttcgtcaaaa gcaatgatcc cgacaccgcc aggatgaaat accagttctc
    51121 tcttcgaagt tcctccatct ggcaaacgaa cttcgtctac agcaacatca ataatttttc
    51181 cgctatagat ttctttgcga ctgattgttt tttcttcaaa ttgctcattg ttcagcatat
    51241 cttctcctgc tttctttgta atcataactg cttttttttc atttttcaat ttttctcaaa
    51301 aactccttat tagtttacca tagataaacc ttagattttc tctaaatata gaaaatcctt
    51361 ctttagtccg atactctttc tagtagtccg tatgctaaaa taagtatgta atcgaataac
    51421 gaaaagaatt caatactcaa cgataaatga catggagggt ttattatgat aaaacgaaat
    51481 tggccgtggc ttctagcatt ggtcttgcta tttctctttg tccgaaacaa tagtttttct
    51541 tttgttctag gacttttatt gataggtgta gttttagttt tgtggggact ctttggttcg
    51601 cgcaggaaaa agggaaaaca agaagaaatt cctgcactga ctgacgaact tgaaactcac
    51661 tatgaaaaaa gcggtatgac agcgaatgaa atttcatttt ttcgacaaac aatgaatcaa
    51721 acaaaaaatg agatcaatca attgcaaatg aatatgcagc agacagccaa acttaaagca
    51781 atcgatctcc gccatgatcc agtcaaagca gcgaaagctt tattcaaaga attggtgaaa
    51841 gaaccaaacc gactgcatga agcaagtcag tttctttata cgcatctgcc gaatctagtt
    51901 gatttgacaa ataagtataa tgagatcaat gaccatgaga tcaaaaacaa acagacctat
    51961 gaaaaactag aagaaagcgc gcagatcatc gaccagctgt cagctttaat cgcacaagat
    52021 tatcaaaaat tcgttgctga ggatctagat gatatcgacg tagagatatc tgttgcgaaa
    52081 cagagcttaa agcgtgataa taaatatgaa ccagaacaaa aggattaact cttttgttca
    52141 taaaagaaga ctcggaacat tcagatgatg tctggctgtt tcgagtactt tttctaaagt
    52201 agagacattc atgtaagaat cgagaacaga ttcaacaagg aggaattttt tatggatcat
    52261 aaaccgactg aaacaaaaga tgttacacca gttaacgata cacttgaaga tttattgaac
    52321 aacccgtttt caactccaac agatacgctg accacttcac aacaagcgga gattgatcag
    52381 ctccaagagc aacagacagc tgctcgttta attgacaaac taccggcgga acgccaagaa
    52441 caagctaaac agctagcagc aaaaatcgat gctaatgatg cacagtctgt catcagctac
    52501 ggatcggctg cccaagcaaa attaagtgaa ttctcacaat cgatgttgaa tcatgtgcaa
    52561 gcacaagata ttggtcctgt aggagattcc ttaactgaac tgatgtatcg tctccaagaa
    52621 gccaatcctg acgaactgcg tgccggagaa gggaacatct tccagcgtgt cttcgggaag
    52681 gtcaaacaat cgatctatga agtgacagca aaatatcaaa agattggtgc acaaattgac
    52741 aagatttcag tgaaattaga taaagaaaaa gacggtctgc taaaagataa tctgatgtta
    52801 gaacagcttt accagaaaaa caaagactac tttgatgcac tgaatattta tatcgctgct
    52861 ggagaattga aaatggaaga acttcaaaca acgatcattc cagaagcgat gaaaagagca
    52921 gaagaaactg gcgatcagat ggatgttcag attgccaatg attacacgca attcctagat
    52981 cgtctggata aacgtacgca tgatcttcgc ttagctagac agatcacgat ccagcaagca
    53041 ccacaaatcc gtttgatcca aaacacaaat caggccttgg ctgaaaagat ccaagcatct
    53101 atcgctacag ccattccgct gtggaaaaac caagtcgtga tcgcattgac cttgcttcgt
    53161 caaaaagatg cagtaactgc tcaacgccaa gtctctgaaa caacaaacga cttattgaag
    53221 aaaaattcag aaatgctgaa aatctcagcc atcgaaacag cgaaagaaaa tgaacgtgga
    53281 atcgtggata tcgagaccct tcaaaccact caaaatgatt tgatcgaaac aatccaagag
    53341 acattgcgta tccaaaaaga aggaaaagaa aaacgtcgtc atgcagaagt agagcttgga
    53401 cacatggaag aagatctgaa acaaaaactg ttggatttaa cccaatagat cacctttcgc
    53461 ttgttactaa aacaaacgcc caacaacagt ttattacaac tgttgatggg cgtttttctt
    53521 atctttcttc taacttctcc attggagtct atttctcatt catcttgctg tgtccatagc
    53581 catagccaaa ataaatgatc agtccaataa ccattacgat accgaacacg atccatgtca
    53641 cagtttgcag acgaagcatc aatacaatac aagtcaaaat ggagacgatt ggcaatagcg
    53701 gaacgaatgg cactttgaat tctccagctt ttggtttgcc aaacattttt ctcaacttca
    53761 gtaagcctag actaacaagc atcaaatagg cgagcgccat gatattcgtt agttccgcta
    53821 atacattcaa tgggaaaaat ccggcaaaga atacagctgc cacaccagcg gcataagtcg
    53881 cttttttcgg tgtacgatgc ttttgatcga tttctgtcat aaacttagga agtaagccat
    53941 ccttgctgac agcaaacagt aaacgagcaa gtgaatacat catcgagatc gttaccgtca
    54001 gtagcgttaa aattgcccct acagcgatca ccgcgcccac tgttccatgt cctacatacc
    54061 tcattgcaaa agccactggg tcattgactc ctagttcagt atacggaacg attcctgtca
    54121 agatcagcgt cacgatgatg taaaggacag tagcaatcag tatcgaacca atgattcctc
    54181 ttggcacatc tttttgcggg tttttgactt cctcggctgc cattgcaacg gcatcaaatc
    54241 ccaagaaagc aaaaaacaca agagctgcac catctagcac accggaaaaa ccaaaaggca
    54301 tgaatggctg ccagttatca ggtttaacga aaaatattcc tacaatgata aacaacgcga
    54361 tgataccaaa tttgacatat accatggcat tattcaaacg taatgctttc ttggcttcaa
    54421 gcgacacgat gtaagtgacg aatatcacta cgagcaccgc aatcaagtca atgtatgtac
    54481 cattttccgg attgtacccg ccagttaatg cttgtggaag ttcggcccct aaacttttca
    54541 aaaaaccttg catatagcca gaccatccgg aagcaacaga ggaaaccgct agtaaaaatt
    54601 ccccgatcaa caaccaccct gtcagccagg cagcaaattc accaaataca acatacagat
    54661 aggcatatgg cccaccaatc actggcactc gcgaagcaaa ttctgcgaaa cttagtccag
    54721 acaaaatgac aacgattgca gctaagacaa atgaaagtga cagtgctgga ccagcatttt
    54781 gattggccgc aacccctgtc accacaaata ttcccgtacc gatgatcgca ccaattccaa
    54841 gcatgatcaa atcagacgtt tttagttctt ttttcatctc actcgtatga ttgagattga
    54901 tctctttctt acgaaacaaa tccattgaag ttcctcccca ttttaggttg gaaaacagcg
    54961 attaaactgt tttcatatac cctaaaagga taccacctaa aatgactaaa aggcaaccaa
    55021 caataacata aatgagctct tttttcgttt ttctttcgcc aaggatgaaa atcccaccta
    55081 aagtagagat aatgatcccc atttgtgaaa gtgagaagcc aacagctaaa ccaagtgatt
    55141 tgactgttag aagcatgcag atgtttccta agccccataa taatccacag atcatgtttt
    55201 tccacacaaa ctgatcgact ttaactttac ggaaagcaaa gaagcttgcg cctaagatca
    55261 ttccgatact ttgaggtaag ataattgaca tcgcatccaa attcgcccag ttgacgatga
    55321 tggtatatac accataacca atcgtagaga agatcaatgc tctaaaaccc ttaccaaaat
    55381 caagcatttt attatctgta tctatttttc cttcgtcatc ttgtcgggca gtcaaatacg
    55441 caccgcttac aagaagagct aaagcaataa taccgtatac ataatctttc gtttgtgtcc
    55501 attcatggaa gaaaacggct cccgcaatcg tattcaaaat taattgaaaa ccagtagaca
    55561 atggtagccc tacagaaaca cccatgtact tcattccatg gaactgtcca ttttgtccaa
    55621 cactccaagc taagccggat aaaaatccga tcaagaaaat ccaaggggtg attacaggac
    55681 taacaacgaa aaagacaact aaagaaaaca gaaatgcacc gatcgtcatt cctagtgttt
    55741 gttgattggc atcgccacca attttaccac ttactaaacc aatactaccc catgccaaca
    55801 tagggactaa tgctattaaa atttccataa ccaatctcct tttatttcac atgataagaa
    55861 acttatcagc gaaaacgtta acaacacaag cacttttttt cgtttctaac gattttctaa
    55921 cgtttttcat tataaaaatt taagattggg aaaaataaag tcattgttgt cccttttcct
    55981 tcagttgatt cagccgtcaa atggatacct aatttttcgg ccagattttt tgctaaataa
    56041 agtcctaatc ctgttgaatg tgttttgcta agtcgaccat ttctcccagt aaatccctta
    56101 tcaaagatcc gtttcaagtc ttccgctggg ataccgatcc ctgaatcttt aactgaaagg
    56161 ctgactcctt gcgcttcctt ttctatgctc acaatgatgt ttccgtgatc cggcgtatat
    56221 ttgatggcat tactaagcaa ttggttgaag ataaaagcga tccatttagc atcggtcaaa
    56281 acagtatgat cctcaccaac gatctcgtag cgaatatttt tttggataaa ataatttgcc
    56341 tgactgcgta tcacaggctg aatgattcct tttagtccat attcttggat gaggtagtcc
    56401 cgcgagaaac tgtcgagtct tgcataatac aaaacttgtt ctacgtattc atcgattttt
    56461 gataattcat tttctagtaa tgtatacttt tgatcgtcaa tatcgaactc gatcgaacga
    56521 actagcaatt tagaagcgga aagtggcact ttgatttcat ggacccatga gtcaatataa
    56581 tctttttggt cttgttgatt actgattgct gattgcatta cttcttggtg ttcacggatc
    56641 agctgattga tatattcttc taccagtttt tcttcttctg tcctcccacc actcaaataa
    56701 ttttgcaaag gggaagtttt ttgtatgtcg gctaattttc cccaccatct tctcttgctc
    56761 aagtaaccac ccagcagata aaaaatcaga aagacgccct caatcaaagc taaataagca
    56821 attgtgctca aatcaacttt gatgtttggc gccagccaca tcacaaagat cgtcaatgca
    56881 ataaaaaaca gccatcccaa gatcaatgtc cactgatctt tcaaatattt aaaaaaattc
    56941 atcttaaccg ctcatccttt cagggaacga tatatccctg tcctactttt gtttcgatat
    57001 atccttggat acctgcctgt tcgatttttc ggcgtaaccg attgatgttg actgtcaatg
    57061 tattgtcatc tacaaatcgt tcgtcatccc acagtgctcg cagcaatttt tcccgactta
    57121 agatctttcc attgtgcttc atcaaaataa ataatagacg atattcattt ttgctcaaat
    57181 caatgatctc tccgttgatt tccatacttc cgttgtcaac attcaacgta atgccattgt
    57241 ggctcatcat ttcactagat aattctgtgt agttgtaaga acggcgaagt aatgcattga
    57301 tttttgcaat cagtacatcg atttggaaat gttttgtcac aaaatcatct gcccccatgt
    57361 tcatagccat gatcatatcc atattcgtat tcctgctgga gataaaaatg atcggtactt
    57421 tcgatacttc acgtattttt tgacaccaat aatagccatc caaaacggga agattaatat
    57481 ctagtaatac aagctgtggt tcttctcttt caaagtctga gaacacttga ttgaaatcgg
    57541 tcgttccaaa ggtttcaaat tgccatttct caagttcctc catgatcaat tgtcgaatga
    57601 tctcttcgtc ttcgactacc atgatttttg ccataaaaaa tccctccatc tttcttcttg
    57661 ctactacaat atcaaagaag cccttgtgaa acaagttggc ttacctggaa aatgtcattt
    57721 tagcaaacgt taaaaaaaac tggaaatatg cgatttaatc gcgtttgtct cttccaagca
    57781 gcttaaattt attatgttat tcttaataat tggtctatta tctgttattt ttctttcgtt
    57841 gtttttgtct tttaaatttt cgataacacc aataaccgaa aagcgttagc actagcaata
    57901 tacctagaag gagtataagt aatcgataaa gatggtattt ttttgtctgt tctatctttg
    57961 aagagacttc ttctgtaaag ggaactcgtc ttcctgtcac tagtaatcgg tgagtgttca
    58021 cggtgtaagg tgtacaagtg ataagtgtga ctagatcctg cttttctcta attgctaatg
    58081 tatttgtttt tgttggaagg acaacaattt tctcaacgac ttcataagcg agcatccgac
    58141 catacacttc aagatagaat cggtcatctt gctccatttc ttcaagatcc gtaaagagtt
    58201 ttttctcagc aataccgcta tgggcggtaa tcacggaatg tgtactctct cctccagttg
    58261 gaaaagaggt gccttgcagg actgtcgctc ctctatctaa caaaagatca ttcgtttcat
    58321 caaataaagg caagctaaca ttgattttcg gaatatagat ggctccgatc atatgttgtt
    58381 cgtaatattc ttttcctgga ttttggacat ttctaaccgc ttgctcaaaa ggatctttga
    58441 cttgtcccat tcctgggatt actgatgtat gagcaagcgt ctgatttttc ttttcatgca
    58501 ctgctaattg ttgctcatgt ttttcttctt tatcgcgttc aagctgcttt tgataattct
    58561 cgatccttct ttgatccaaa taattgctga gagcatctgc taaaaatgga tatgtaaaaa
    58621 ctgcagctcc ggcaagaaac atcactgcca taaataattg taataaaaga ctgatttggg
    58681 tttgaggtct attacctatt ttctttttca ttttcttcac cttcttattt aaaaaaactg
    58741 cagcaacctt tataaaaccg attgctgcag cttatttttg ttgcttatac ttcagacttc
    58801 attttagatt tacggtacca gctgtacgct ccaatcatca aacttattcc gattagtaag
    58861 aatgccaaga gcccgttccc accagtagca ggaagtgacc cgcgtttcat attcggtact
    58921 ctttctggcc ctggattttc tactcctacg atctgaattt cttcattata gcttccataa
    58981 gagatgataa attcagtaaa ggctgcctca cctgttggaa gtacataacc ttctggcgcc
    59041 atggtctctt tcatttgata ggttccataa tctaaccctt gaacctcaaa gtatccattt
    59101 ccatctgcga caaattctgt tgcttgtccg cttgttgccc actcaattct atctgctcct
    59161 gattcataaa cagctaaagg cgactcccct ttataaaata ttgcgtattc agaacggtct
    59221 tcattccaca attcgaatct tgcatcttta agcaattcac tgcttgatgc atcatatttt
    59281 tcaaactttc ttccacctgt tgtgactttc tctggcggct ctactccttc ttcataatca
    59341 aattcatcat ttcgtccgat ttcaataacc gctgtgttgt tatggaaatc atccgcttct
    59401 agttctgtgg aaaccttcaa attatacgtg atcgttaaat ctcctccacg tgcatctgct
    59461 aatctaccta aagtatctac tttggctact ccattttctt ctgtcaaaat cgtcacgaca
    59521 aacccgttgc ttactacttc tactatataa tcttgtcctt ttgttaaaat cgtctcgccg
    59581 gctcgcactt ctatttcctg atcataataa gttagaccaa ctgtaggcgt atctgtgatt
    59641 ttgtaatttt tgataacagc gcttccgttt tcaaggacag aatcgatgaa ataaggaata
    59701 ggtgctgtga tcgtgtaaga agccgttttt cctctttcta gatcaatata agaaatcgtt
    59761 tcttgttctc cagcttcatt aataatcgtt acttgtctaa ggtcgctttc ctctacattc
    59821 atctgtttat ctgcttctct gatttcgttt ttcggataca aatgcacatc tgtattgtat
    59881 gtgtctttcc atgtagaacc atcccacacg ccatccacca tatcaggcat catcactggc
    59941 atcataacaa ccattggaga cgcgattctg gaaatatgag ctggcgaata agtttctaag
    60001 aaaagataga ctttatctct agaagaaggt gcttcttccg tcacttggac ggtagagaat
    60061 accgcttctc cagcttcatt cgttgtttgt ttgtcaatac ttgtcagtcg atattttaaa
    60121 aaccaacttt ctgtgtgccg tttttgaatc cattcaatcg cttcggcaga attaagaccg
    60181 tcttctcgtt ccggtgttaa aggattatct cgaatcaaat cgtaatatac ttccgttacg
    60241 tcaaacaaat caaaatcgac tcctggaata ttttcttcac caaaatccgt agaaaccaat
    60301 ccgctattcg gtcgttcttc cggaacagat gagaaacctt ttttgtgtaa tgtaatcgtc
    60361 acttcacttg gtttttgtgc gacttcttcg gctttgacta gttttccgtt cccgaaaatc
    60421 cctattcccg cagtaacgag taacagtaca ctcattcccg tgacaatcat ttttttattc
    60481 atttttttct ccccgttctt tttttattaa taaaacagca cctaacaata aaagaattcc
    60541 tagtaaagaa atcaacgttc ttgcttcatt cgtttgcggg aatacggacc attttcctga
    60601 ttgacctgga ttgcttggac cactcggctc tttcggtttg tccgttgttt cttttacggt
    60661 ctcgttataa acacgtggtg ttgcggattc ataggcagag actggaactt tcccggattc
    60721 taattcagcc atctcctgtc cgttaactac tacatattgt ggttggcctt ttgcatccac
    60781 ccaaaattca gggatgatga cctcgattct cttacttgct tcatccatct cgtaaccttc
    60841 cacacctttt aattcttcaa aataataggt gccagaaggc aagaaacgtt gtcctgtcgt
    60901 aacaaggccc tctttatccg aaatgaattt gcttacattt ttgtcattca aaggatcatt
    60961 gtctgctggt ttgatccatt gatttttcaa gtcattagca ggagccatat ctaaataata
    61021 tttcccccct tctatcatct gatatagagc aaaaacagca ccttctaatg gttttccttt
    61081 ttcagttgtt cctctttgac gtccatactt gaagaagtat ggatctctta gataaccgac
    61141 atttttagga tagatatgaa tctcttgcag ttcctcggtt gattctgtcg ggtgataaat
    61201 tggcaaaata gcagcaattg ggatagctgt ctgatcgata tcaacatcca atccaacttc
    61261 tggatcaatc gattcttcga aaatcaaata aactgcatcc cgatcttggt ttttcttagg
    61321 tgctttgata cgtgcaatcc cgtctcctaa tccgccaacc gtatctttcc cagttgttac
    61381 cgaagtccct atttggacaa gcctttcttc tgtgattagc tgacggatat tgtttctgtt
    61441 cgtttcagcg atttgctgga cgaattcttt aggagtcatg ttttcagcag cttttttttc
    61501 atgataataa tcggtcatgt cgtaaatggc aaatgtcgct ccatttagtg gcaccgtctg
    61561 tgaaatgata tctgctgttt cccctgcttc ctcagagata gccaagccat cattttcatg
    61621 gtattcaaat tgatcgttat aatcgatatc tcgaatcatc cgtttatgca acacgaattc
    61681 cacgacatct tcccctgatt cttctgccga catcgcatgt ggaagaagga ctgctgcaag
    61741 cggtagtaaa acaagtaatt gaagcatcaa acacaacagc tttttcatta ccttgctccc
    61801 tcctttttag attgtctgac aaacaaacca taggctgctc ctgcaagcgc catgaagaat
    61861 gcagcaagca ggatatagaa taatcgtccg gatcctcctg tagcaggcaa cggattttca
    61921 ggatcgttcc cgacactaag ctgtaatctg attcgatttg tctccaaaag ttcatattct
    61981 aactcttgct gtagatcagg cgtctctgct tcttcgtttg gataatacga aatctcaact
    62041 tttagtgtac ccgcttcttt tcctggaact acccgatcat tttctatgtc aggttcttct
    62101 cgataactaa tttctaaaat aaagtaacct ggaagttttc tatagctgtc aggtgacttc
    62161 acttccttga tccgatagac cccttccaac aagtctgaag cattgaatag ggaagaatcg
    62221 tttggatctg gtgccaagcc tccctcgatg atttcatact ctcctgcact attttgtttc
    62281 tcaattgaaa attctgcgcc ttcaagacgt cggctattca tactgtcaat tttcaaaagt
    62341 tccaaatcga ttggcgctag ttcatcttct aaggttactt gtagtacacc atcgatgatt
    62401 tcatagcctt ccggcaaggg agcagtttcg tcttcgatga ccgtatcttc aatgataaac
    62461 ttaccttctt cattcagtgc aaactggaac acttgatcag atagccgata cccatttggt
    62521 gcgacagatt ccgagacctc atattcacca atagacagat gcagaggttg gtcgtaattt
    62581 aaatcgacat acttttctac tcctacggca cgagaataga agtatccgat cccaggcaaa
    62641 cgtttcgatt cttctggttc taacggatta ccagtgtatg ctcgatacag cgggaaggaa
    62701 gaatccccca ctttcctgat atcgaaacct gcaccatcta atgtatggcc ttcatggtct
    62761 aattttctaa ctcggatctc ccgataatca aacgtattgt aagcagtgaa tgctacccat
    62821 aaacgatcct cttcatctgt tgtatacgtg agatattgcc aattttcttc acctgtttgc
    62881 ttgagttgga tagtccctat agcattatcg taaagtcgca agatccatgt gtcattttca
    62941 tcaggttctt tgaaaccttc tgggttctgg ctctcaatga ttttgtattc tgcatagttg
    63001 gtagtttctt cactatcctt ataaacaaat gaatctggct ctccgattgg atgaataact
    63061 ttctcaccat ccacgattac atatttcccg tcttcatcta ctgaatagaa cgtgagtctc
    63121 cctttctctt cctctacttc gttcacacca gaaagccctt tcgctactgg atatccgatt
    63181 tccagtccgt taccatctgt ttcataaagt tcaaactctg cgccattgat tggcatatta
    63241 ctgccttcaa ttagtttatt gatattcatg tggattggct tgaattcatt tcgcatttcc
    63301 agtttgacat acaactcatc atactctgtg ccttctatgt taggctcttg tacaacagaa
    63361 agcttgtgat attctccttc ataataggaa ttcggatctt taccttccgg tccgccgact
    63421 ctcgaaccag atgtatattc atctacaagc tcgtagtgac ctaacatctc atcttcgttg
    63481 gctgcatatt ttttgatttg gaattgatac gtctcatcta ctaactgata acgtggtggt
    63541 ccagcgatct ctctgatcca aaatatgtcg ctgactgctc cagtttcatc tcctaaaatc
    63601 ggcatcttcg tttcaaagat cgctattccg tccgtggtag ttttacttgt ttcgattggt
    63661 tcggcttccc cactctctgg attttggtca tataatgcaa attcgactcc agccaacggc
    63721 tcgccatttt gacccttctt gctgacttgg aaattacggc ctttatgttc gtaacgaatg
    63781 gaagaagatg ggaaatacat ccgtccagta gtgatatcat tctcataatc ctccaggttc
    63841 tgaatatagg ccatattgtt cactgtgcaa aaatttccgt cttgagctcc cgcatcaagt
    63901 tttacttggt acttgatcct gaccatttcc ccttcaccta aagaaatcgg agaaaattta
    63961 taagcttggt tttcccgtcc gacatacgtt gtcggagtcg ccactacttc tggtggggct
    64021 tgtccatgac gttcttcatc ccatatttct ggctcttggt acttcatgcc gttttctcct
    64081 ggatctagat ggtaaaactg aatatctgcc gatctgccag ctccaaatgg tgagacatta
    64141 aaaccagttt catcataaag tgtggcttgc tggatcgttc tcttgaaggt agaagagata
    64201 tcctccaagg ctgtaacaat gtcattcttg ttgttcgcat tgtaatatcg cggtgttacg
    64261 ccatcttctt ctaaatcagc aatatttttc aatacatttc gtccaatagc atctagtcgt
    64321 tgtctcccgc taacgtttcc atcgattcct aaaccaatgg agaagatact tggcgggttc
    64381 tcttgatact tgtttttcag ccaatgatga taagcaactg tgttgatcgc agatgacttt
    64441 tcttgcgaag taggactgcc attcgtattg ttattagaag aaccatcacc aacccagtga
    64501 gtcgctttat tatctccttc ttttacctct ccataacgat agtgtacatt tacttcatct
    64561 tctggacggt taaagtcaga tgcataggta actggatgag taaaccctgc attagaagta
    64621 ttcccagaaa actcctcaaa atttctgaac aaaacgtcat tatcttcagc aatcttatct
    64681 tccatcacag tccagttgct ccaagctcca ttagtgctcg tacgataact tgactgaatc
    64741 ggtgcataac tgaaggtcgg tgtcccatct cccacaacga ttaggatttt ttctggattt
    64801 ctattttctc cgccattgtc tttatacaat gtttcatagc catttttaag ccctagtgta
    64861 agcggagttc ctccgattgg tgtacgattt aatgctgtat tctcacttcc cgtcaaacga
    64921 ttgatatcat ttgtcaatgg aaagatgtcc gaactgattt gctcatggtt attgatagct
    64981 gtactattat ggtaaaaatt caccataccg attcgaatat ccagactcgg gtcagagagc
    65041 agatctttac tcatttcgtt tactgcctca atcaacgcag catttttagt ttgactattg
    65101 gtcccagcgg ttaattcact catactcgct gacttatcta gaacaaaaac gatatcgatt
    65161 ggactgattt cctttttctc gcccccgatg acatctagat agacattgta aagggttgtt
    65221 gcatcttcag gatgtagatc agatgctgtg ctgcttggca gaacaggttc tacccatttt
    65281 ttgatgtacg ccccgttata atccaagtaa ctgttttcaa aattccgttc atttccccaa
    65341 agctgaacgg tttgagctgg aacgtttcta tcttcttcgc ctgcagttga tccattatta
    65401 gtagcatagt cgtaatttcg ccagttcgct cccccgtttg tataatcact atcatcgatc
    65461 aagttctctc cgtcatatgg cgagcctttg tctccttgat agcgttcatt gctttgtgtc
    65521 caatttccta acacttttgt atagtcattc gttgtaaact tcgggtagcg atgctgttcg
    65581 ttttcaactt ctccgctagg atagatatat tcataggggt cttgcgtagc tgttggccca
    65641 agacgctcca aaataccgtt gaataactgg cgttgaatgc gctggagtgc ttgaccgctg
    65701 ggtacgattg gttcgtccag cttttccatc tcattttctt cgctacgttg aatttcagcg
    65761 gaatcttctg tatcagtttc attttcttgt aattcttggt tatctattct ttcatcaacc
    65821 accacttgaa gaggtagtta cccttcgttc acatcgggga tcttttctgt ttcaaaaatc
    65881 aatgtgccgg tttctgcttc ttttgaataa acttttccga cataccattc ttgaccatcg
    65941 atcgtctcga cttttaggtc ttctccatct tcatcatagg aggatagacc tgttccacga
    66001 acgtttttta cggtaccaat cccggcggct gccgcatcga ttgctaaacg tattctacct
    66061 tcattggcac tttccttttt ttcaaaagcc agatgccatt caagggtttc ttctttttca
    66121 atatacttcc cttcaatttt tgcatagtcc tcatctaaga atacctcatc ctcctttgtt
    66181 tctgttgact cagcagctac atccagggtc gtcatatgat agactgactg gaaatatggt
    66241 ccaaatagca aactgacagt tactaactgc aaaagcttca attttaaccc tttcacatcc
    66301 ttatactcct ttcaaaaata tttgtcttct ttcacaacaa tcaacaaaac aatgcccatc
    66361 taattataat ttaatttaat tttaatttta aatcaaatga tatccttttt agttaaaaaa
    66421 caccaattat acaacattta ttattaaaat taaattataa aattttataa cgttctcatt
    66481 taacaaaact taagttatta agacaaatga ataaacaact acgctttcct cgaaacaaaa
    66541 aaataaagca caaatgcgca tttacgcact catgctttat tcgtacaatt aattcagata
    66601 acggcagcgc ataggatgcc aataacactt cctaaaatag ctcctcctaa aatgtcagta
    66661 ggataatgta aaagtaaaaa aatcctcgaa taagcgatca aacaagcaaa taaaaaggct
    66721 aatattcctg caactggact taattcgaac aacgcagcta ctgataaaaa ggctagcgct
    66781 gtatgtcctg aaggaaaaga agaagtcttc ggtttacttg tgtaaaggac aagccgacga
    66841 tttttttcat aaggtctttt ccgtcttgtc gtttttttga taaaaagcaa accaacaaaa
    66901 aaatagatca aactgccgat aagaatggct agaccatatt ctctagtatc aggtatcaag
    66961 actaaaacag cagcaaggag caaccaaata aaaccaccat tagagatatt actgataaat
    67021 ttcaaaaaat tgatttttcg actatccgtt ttccgttgct tggcgaactt gttgataata
    67081 ctatcatcga ttttagcaat caaacgcaac atgttattcc tcctttttaa gaaccttttc
    67141 ttgcgtacga tggataaaaa gcaggacttg aaaataaaac aagaaactga aacctaataa
    67201 agcaaaatag attggtcctg caaaccagaa tgcgacaaga aggatcaacg tgcctgccaa
    67261 atagaaaagc gcgcttttga aatcattaaa aaacaagaaa aatgcagtaa tccaagaagc
    67321 ttctttttgt tccagttgaa gcaagatttt gtaactaaag agaagcgcgc ttaatagaag
    67381 caaaaacaac gtagtataca tcaatgtata gccaattccc ccaccccaat agcggaaaat
    67441 ctgataatcg atcaatagaa gaagaaaata aacacttgct aaactatctt gctttccata
    67501 aagagagaag ttctcacgaa actttttcca gaatagtgaa ccgagctttt tctcttcatt
    67561 ttttttgtaa tgataaatca tatacagaac tgttcgactt gcagttccta atgtgaaaac
    67621 aggcaagacg cacaggaacc atagtagctg taaatggata agacgtggaa tccattcaat
    67681 gatttctaag aaataatcat tggctttttt accaatcgat cgattcatca tccttttgaa
    67741 cctcctgtca aatccatccc ttcaatgaaa taacgttgtg caaaaaagaa cagcaaaatc
    67801 gtcgggatca agacaagtgt tgctcctgcc atcagataat tccattgtgt cgttgcttgg
    67861 ttctgaaaaa cttgcaagcc aatctgtaac gtgtattttt cttgatcttg gatatataac
    67921 agaggaccta agaaatcatt ccaagctgcg ttgaaggaat tgatcgcaat ggtaatcaag
    67981 gcaggtttcg tcaatggaag catcaaatga ctccaaatat acaaatgatt cgctccgtcg
    68041 atttcagcag cttcgatcaa ttcattattg atcgataagt aaaattgacg catcagaaat
    68101 atattgaacg cattgccgaa gaacgatgga acgatcaggg gcaaataagt acctacccag
    68161 ccgatcttgg agaataatac atattgaggg atcatcgtta caaaccccgg gatcatcatc
    68221 gtagaaagaa ccaaagcaaa catcagcttt ttcccaggaa aatcaagctt cgcaaatcca
    68281 taagcaataa aagaatttga aaggacatta ccgatcacta ctagcacagt gatgaataat
    68341 gtatttcttg catagcgcca aaaaggaaag gcggcaatcg tatccagata gttttcccat
    68401 acgatttttt ctgggaaaaa ggtcggagga taacgaacga tttcttccat tggtttcaat
    68461 gaagtaaaca ccatccaaag caatggaatg atcaaaatga ttcctattac tgtcatgagg
    68521 acataactta gtattttttt tgtttgccga ttcacactgg tctttttgaa ataatccatc
    68581 atttgccgtc acctccagaa taatagaccc acttaggtgc aagcttcaaa ttgacaaacg
    68641 tcagaaccaa cacgatcaga aacaggatca ttgacatagc catcgcataa cccatatcaa
    68701 aagctacgaa cgccttgttc cacatatgca gattataaaa aagcaaagaa tttgcaggtc
    68761 cgcctgttcc atttttcgtc atgacataag cttcttgaaa aatttggaaa gaaccgatcg
    68821 tagaggtgat cacatcgtaa aaaataatag gagtgattaa tggcaaagta atacttttga
    68881 actttcccca aacgcctgct ccatcgattt ctgctgattc atataaagat ctaggaacat
    68941 tttgtaatgt agctaagtaa agtagcattg ctcctccaga actccatatt ttcatcaaaa
    69001 tcaacgcagg tttcgtccat tgtggatcaa acagccaagc tggtccaggg atatggaacc
    69061 agcccagaaa tgtgttgatc aatcctgcag atggagaaag cagctgcatc cataagatgt
    69121 agactgctac tcctgataag actgccggta aatagaaagc tgtacggaat acactgattc
    69181 ctttgatttt ttgattgagt actgtggcta aaaacacact gaaaatcgtc gtcagcggta
    69241 cattgaagat gacgaaataa acggtgttgt ataacgattt ccaaaataaa tcatcgtgaa
    69301 cgaacattct tttgaaattt gctagaccaa tgaaattcat cttggatgtc aaattataat
    69361 cggtgaaact accaataact gaaaaaagca taggccctag cataaatacc aagaacccga
    69421 taataaaagg cgagataaat aaataggccc atcttgcttc ttttttcttt cggatagata
    69481 aacgcttcaa attttcttgc ctcctctgta cctagacagt caaaaatgga ttattgattt
    69541 tgcttgacta agttttctac tgctttttgt gcatctgcca atccttcttt tggtgatttt
    69601 gttcctaaaa gaatctggtc aatctgttca ttcactaatg tcgtgtaatc cggagcatct
    69661 aaaggaactg gtgtgatcac cgtattttta aagttttcgt ccgccatttg atagatcatt
    69721 tttcctttat ccgttaggtt gtcattattc actaaattct cattggctgt cttgctcgcc
    69781 atgatatcaa aacttttttc gccgaatttt tcttgtactt ctggagaaga aagatatttg
    69841 atgaattcat aagaggcctc aggatctttt gctccgtatg gtacttccaa gacgaatccg
    69901 ccaccccacg accaatggcc tgaaccttct tctttttctg ggagctgcat cacgccaaaa
    69961 tcaaaatcat ccggtgcatt ttccatcaaa ctagagtaat aattgatatt ttgggcacgc
    70021 atggctacta atccggaaat aaatggatca gatacaccag acccaaattc ggcttctaat
    70081 ttattgatcg tatttttccc ataataatct tgccagtctt ggatccactc caaggcttcc
    70141 actttatttt tagtatcaat cttgactttt tcatctttgt caaaccaact agtcccgtta
    70201 tctgcgttta gcgcccatac atcagcccct aaattccata atggataaaa accgatgcgt
    70261 gtaaattctt ttccttcttt tttatctagt ttacgtgctg tttcttctaa ttcatcccaa
    70321 gttgtcggta gatcttgttc actgattcca gcttctttaa ataacttttt attataaaaa
    70381 atgacttgtg tatctgtatt gaatgggatc gcataaggat caccttcata ttctactgta
    70441 tcccaaagct gcggataaaa atccttagaa gtgtcttttt ctacatattt ggagagatta
    70501 gttgcttgct gtgcttctgc tctttgggca acggaattta tgtcctgtac aataacatcg
    70561 ggtgcatttc cagctgttat tgcagataaa gatttagtcc agatgtcacc ccatggctga
    70621 tacttataat ttacatggat ctcgttttgt gattgattga aatcctcaat gatttcttcg
    70681 atagcttctt ttcgtgcacc ggatccccaa aaggaccaga aatcaatatt ttttcttcca
    70741 tcacttgttt tttcagaaga atttgctgca cttgaactgg catcgcttgc attacttgat
    70801 ccgcatcctc ctaataaaaa caatgctgaa cttgccagca accctgtaaa caataatttt
    70861 ttcatatttt acctccaaat tttaatgtaa ccgatgccgg ttttaatata acgatatcat
    70921 tttgttctga aaataacaat ttataaggta tgattctaaa aaaattatta atgataccaa
    70981 tactttatat aattcgcgag cgctttcttt gaatttttta atctttcgta gcagaatgag
    71041 aatgtattaa aaatagatta ggaggaattt tgatgtttag acaccagaaa gaattgcagt
    71101 ttgaagcaaa accagatcgt ccgaatccat taatcgcgaa atatctgcag gagctgatcg
    71161 gcggccaata tggcgagatg agtgtagcta tgcagtacct gttccaaggc tggagctgcc
    71221 gaggagaaga aaaatataaa gatatgctga tggacattgc aacagaagaa atcggccacg
    71281 tggaaatgtt ggcgacaatg gttgctcgtt tattagaggg tgcgcctgtt gaagatcaag
    71341 aagcagcgat gcaaaaagat ccaacaatcg gtgccattat ctctggaatg aatccacagc
    71401 acgcgatcgt agctggctta ggacctcgtc ctgctgacag cgtgggcaat ccatggagcg
    71461 gtgcctatat cattgcgagt ggcaacttgt tagcagactt tagagctaat ttaaatgccg
    71521 aatcacaagg aagacttcaa gtagcacgta tttacgaaat gatcgatgat cgtggcgtaa
    71581 aagatatgct gtctgttctc cttgcaagag atagctatca tcaaaatcta tgggaatgtg
    71641 cagtgaaaga attagaagaa aaagaaggtt caatcttagt cccaagtact ttcccgcgtg
    71701 acaaagaacg aaaagacatt gcttatgact tctataactt ctcagaggga gaccaaagta
    71761 gtgaaggttc ttgggctagt ggcaaagcac tggatggcga aggcgaatat caatggttga
    71821 aagaacctaa gatcgaaggc gctgcaccaa aattagaacc agtaacacca aaaatgtatg
    71881 ggacacctcc attcaagaaa taaatatcta cccgtagaaa cacccgtttt ttgttccaca
    71941 cgctttgtga gcaaaactga ctaaagtcat taatcataac cacccttcaa aagggtggtt
    72001 ttctctagag ctataagctc aaatcaccgg ccagcgccta aagacgctgg ctttcatatt
    72061 ttatgttcaa gccatattgc ctttgccagt tttgcccacc tcttaaaagg tttatgtact
    72121 actccttagc ccttaaaagg atcgtcttac tctcgtacac tcagcttatc taacgcacta
    72181 tcatgttttt cttgttcttg aatgtacttt ttgatggtcg cttcattttg tcctactttt
    72241 gtcacatagt atccttccac ccaaaagtgt cgatacccaa atttatattt tagatttgca
    72301 caatctcttg atgatctcct gaatattggc tcgatattga ttataaatta tttttcttct
    72361 atactttggt gtgaatacaa tgtggtattt acacatctac tttgtacggg ctaaactatt
    72421 tccctttatt gctccacccg catagcaagt ggttttgtat ttcaatcgct cggcgcgctc
    72481 aattaggtct aaagacaata aatctaaaaa cccgctgctt cactgacaga aacaacgggt
    72541 tttcagaaaa aaatgaaatg aaaaagatct cttacggcaa tctattttat ttttttgatt
    72601 ttttataaat ggaaaatgct tcaagaagtc caagaaataa agccgtataa aaacaagaac
    72661 ctatgaaatc tttatttatt agatattcaa cagaaatccc gataacacta gccaacaata
    72721 tatttatcag aagtgtaaaa taaggatgct ttttatagaa tagaactagt gttgttttca
    72781 tagactctcc tttcttcata tttccaatta atcacaaatt cacggcatta ctagaaaaat
    72841 taaaggggcg cagaagtgga aaaatactct tcgactttcc ctacaaacca ggccatcttg
    72901 tgtttaataa ctataccaaa tctaaggtac ctctaaatct aaattccatt tgtggcggtg
    72961 acctccaatt tttaactctt ctatctccca tccagtatac ataaccttga tacttcgacc
    73021 acttatatat cgaacacaca aatacctatc cattgcagga gtactaccta acttagttgc
    73081 tacttgcatc taaataacag ctgaaaagat aggacttact cttagtaaag tatctgaact
    73141 attaattttt aaactatcat ttttatcctc aactacatgc acatctgttg caacttcact
    73201 ttctgtctca tccagataaa tgattaagga atcgggaatt gcaatatctt cagctgacgc
    73261 tggaatagtt gagctaaatt agtcatcata tctttattat aaaataacca acagcaaaaa
    73321 atacaatgaa aaacaaactt ggaactaatg tatcattaat aaatgttgaa aaattcagca
    73381 actcattact gtatgatttt agcagcccaa ccaacatata ccctataaaa gctaataaga
    73441 tggttaggaa tcctttagaa tttttactca ttcatagaca cttccttaaa taacttttat
    73501 tatagaaggt attgtaaata ataatattga caaaaagtga ctcaaaataa aaaaaacctt
    73561 acattatact ggaatgaact gtattgatag tgtacctaaa agctctactg acataagatc
    73621 gtgtaatcgg taaagtaatt ttattaatta tacgggatgt aatcaattag agaataaact
    73681 aatcataaaa ggtactttta cattcataat tgtcgctttg agattctact ttggttcact
    73741 atctgaccca attgcacatt ttcgatcatt acaagtattg gtgtcgttag aacaactaaa
    73801 taaaaactag cggtagattt ttcagaatct atgctaattt ctgtatggat gttccagtga
    73861 tggcaaattt ctcttttcat tgtttttctt gtcgcatgat atgccttttt gtgttattca
    73921 gttaaactat agaaattctt tcctagacag atcttgatcc caaattttac gtttttgagc
    73981 atcgatatag tttaaaatga cattactcat atctaaagag tttagatttt ttaggactaa
    74041 aactgtcagt tgttcttttt cttctttctg ttaaagtatt gtcgcgactt ttcgtatacg
    74101 ttaagatatg tcgtgaaaaa acaagttttg tgacacaaaa aaacgaatga cttgaggaaa
    74161 tcacctcaat cattcgttta aaatgctata tattctttag tttaagatac ggaaattaat
    74221 gccatcgacc acactagtag aatgaacgac atttacttgg ccttttttta atttcgttat
    74281 gtttagcata taaaaatatt atagagttta cttacaatgc ttaaaacata tactgtataa
    74341 tctgatcaat tttagccatg tcttgcaatg gtaagttttc tatttttttg agttttcgtt
    74401 ccttaaaatc aagagatttt aattgtgtaa taattacttg tccttttata tctagctctt
    74461 caggtaatga gtaacgtgtc ggtaaattct ttatagtgga agtaattgga catatgaccg
    74521 aaaacattgt tttacggtta aattcataac gagagacgac tagtcctggt cgtctttttt
    74581 gaatttcttt tcctacggag ggatcaaaat caatccatac aatatcacct tttttaggaa
    74641 tataaattct ttcttctgac actataaaat ttctctccct tcaggagtta aatcttccca
    74701 ttcgtctttc tcataatact cggcctcttc cccaccacta aatggatctt caatttttgg
    74761 aactaacgta attgttccat catcagaata cacaacgata tattcttggt tttctgaagg
    74821 tttctttccg ttatcagaag gtaaagttac cactacagaa cttccttgta atctagattt
    74881 tgtaacaagc attatcatca ctcccttaat aaaagtatac tatataacac taagtaacgc
    74941 aaaattcccc t
//
LOCUS       DAZKKZ010000006        61729 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.006, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000006 DAZKKZ010000000
VERSION     DAZKKZ010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 61729)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 61729)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..61729
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.006"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(59..187)
                     /locus_tag="ACG8LA_000441"
     CDS             complement(59..187)
                     /locus_tag="ACG8LA_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HFQ0202774.1"
                     /translation="MDQKEKMKELIKKKQGGGRSKQMETPKNDRKNMRKGPKIFNK"
     gene            complement(190..1563)
                     /gene="rlmD"
                     /locus_tag="ACG8LA_000442"
     CDS             complement(190..1563)
                     /gene="rlmD"
                     /locus_tag="ACG8LA_000442"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HFQ0202775.1"
                     /translation="MTEQQIVKKNERYTVEIVDLSYEGMGVAKIDGYPLFIENALPGE
                     EVEILVVKAGNKFGYGKVETFITQSPDRQPVENNALLRIGIAPLAHLKYEQQLVFKQK
                     QVEHVMAKIAKMPEVPVLPTVGMAEPFGYRNKAQIPVRRIDGQLATGFYKKNSHDLVP
                     IEDFYIQDPVIDQAIKVVRDILQRFQVRGYNEEKNEGQLRHIIIRRGHYSHEMMVVLV
                     TRKEKFFKSKEIAEAIHEELPEVVSVIQNINEEKTNVILGDKEKVLYGRDYIEDQLLG
                     KTYRISAKSFYQVNTQQAEYLYQTAIEFAELDKKDIVIDAYSGIGTIGLSLADRVDKV
                     YGMEVIPEAIEDAQFNALNNKIENVHYEVGKAEKVMKKWQEKGIKPSVIVVDPPRKGL
                     DHHFIESAIEMSPERIVYISCNPATFARDAKLFAEAGYAVKKVQPVDLFPQTHHIELV
                     ASFVKGE"
     gene            complement(1674..2729)
                     /locus_tag="ACG8LA_000443"
     CDS             complement(1674..2729)
                     /locus_tag="ACG8LA_000443"
                     /EC_number="2.7.1.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003951 - NAD+ kinase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HFQ0202776.1"
                     /translation="MKKARVIYNPTSGKELLKKNLADILQALEEAGFEASAYATTPEP
                     DSAKNEACRVAELGFDLVVAAGGDGTINEVVNGIAPLEHRPKMAIIPAGTTNDYARAL
                     KIPRDNIKAAAEVIKKHQTVKMDIGLSDNSYFINIAAGGYLTELTYEVPSELKSIFGY
                     LAYLAKGAEMLPRVKPIKMRLKYDEGEYIGNASMFFLGLTNSVGGFEQIAPDAKLDDG
                     KFSLIIVKTANIFEILHIAALMLNGGRHVDDPRIIYTKTSSLFVETEDDINRPVMINL
                     DGEYGGEAPMHFQNLHQHIEFFANTDQIPDEAITGTDEEELEVVSKEFVKEVERLTDE
                     DIDGDGKIADETPNQKN"
     gene            complement(2739..4169)
                     /gene="gatB"
                     /locus_tag="ACG8LA_000444"
     CDS             complement(2739..4169)
                     /gene="gatB"
                     /locus_tag="ACG8LA_000444"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016884 - carbon-nitrogen ligase activity,
                     with glutamine as amido-N-donor [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HFQ0202777.1"
                     /translation="MNFETVIGLEVHVELKTNSKIFSPAPAHFGAEPNSNTNVIDWGY
                     PGVLPVMNKAALEFGMKAALALNCEISKDTHFDRKNYFYPDNPKAYQISQFDQPIGHD
                     GWIEIEVEGKKKKIRIERVHLEEDAGKNMHGIGGYSYVDLNRQGTPLIEIVSEADMRS
                     PEEAYAYLEALRSIIQFTEVSDVKMEEGSMRCDANISLRPYGQEEFGTKAELKNLNSL
                     SFVKKGLAFEEKRQAKVLLSGGEIQQETRRFDETTNKTVLMRVKEGSSDYRYFPEPDI
                     PKFVIDDEWIQKVKASLPEMPASRRERYIREFGLPEYDAMVLTLTKEMSDFFEAVLEN
                     GADAKQASNWLMGEVSAYLNSEKLELAETKLTPENLAGMIRLIADGTISSKIAKKVFR
                     ELITNGGEAQEVVEKNGWVQLSDPNKLLPIINEILDNNQQSVDDFKNGKDRAVGFLVG
                     QIMKATKGQANPGVVNKLLKDELAKR"
     gene            complement(4166..5638)
                     /gene="gatA"
                     /locus_tag="ACG8LA_000445"
     CDS             complement(4166..5638)
                     /gene="gatA"
                     /locus_tag="ACG8LA_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030956 - glutamyl-tRNA(Gln)
                     amidotransferase complex [Evidence IEA];
                     GO_function: GO:0050567 - glutaminyl-tRNA synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HFQ0202778.1"
                     /translation="MTELHNRSLEELHHMLVSKEITVQDLTKATFERIKETEPEVEAF
                     ITLNEEKALEQAKALDEKGIDESNVLAGIPIGIKDNIVTKDILTTAASKILYNFEPIY
                     DATVMDKIYQADMIPVGKLNMDEFAMGGSTETSYFKKTKNAWDPTKVPGGSSGGSAAA
                     VAAGQIPVSLGSDTGGSIRQPAAFNGIVGMKPTYGRVSRFGLIAFASSLDQIGPMTRT
                     VKDNALALTAISGYDEKDGTSSGVSVPDFAEGLTGDIKGMKIALPKEYLGEGVAPGVK
                     EAVLKAAETFRSLGAVVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRSEN
                     VKSLDDVYVNSRSEGFGEEVKRRIMLGTFSLSAGYYDAYFKKAGQVRTLIKRDFEKVF
                     ADYDLIIGPSSPTVAFGIGENINDPITMYMSDILTIPVNLAGLPGMSVPAGLSEGLPV
                     GLQIIGNYFDEKTMYQAAYAFEQATEFHKQQPAILGGKDE"
     gene            complement(5638..5943)
                     /gene="gatC"
                     /locus_tag="ACG8LA_000446"
     CDS             complement(5638..5943)
                     /gene="gatC"
                     /locus_tag="ACG8LA_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030956 - glutamyl-tRNA(Gln)
                     amidotransferase complex [Evidence IEA];
                     GO_function: GO:0050567 - glutaminyl-tRNA synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA];
                     GO_process: GO:0006450 - regulation of translational
                     fidelity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HFQ0202779.1"
                     /translation="MAISEEQVKHVAKLAKLAFADEELASFTDQLGKIIDMVEMLEEV
                     DTEGVPFTSNVVETVNVMRQDRAQAGWNRDELLKNVPETEDGFIKVPAIIDNGEAGA"
     gene            complement(6049..8085)
                     /gene="ligA"
                     /locus_tag="ACG8LA_000447"
     CDS             complement(6049..8085)
                     /gene="ligA"
                     /locus_tag="ACG8LA_000447"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003911 - DNA ligase (NAD+) activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HFQ0202780.1"
                     /translation="MEHEMTIDEAAKRAEELRTRLNQWSREYYVEDKPTVEDYVYDKE
                     YAELVAIEEQYPDLITSDSPTQRVGGKVLEGFEKVTHDIPLYSLNDVFSKEELIAFDQ
                     RVQKAVGRVVDYCCELKIDGLSVSLRYEDGNFVRGATRGDGTVGENITENLKTVRSVP
                     IKLKEPMNIEVRGECFMPKRSFVQLNQDREAEGKDIFANPRNAAAGSLRQLDSKITAK
                     RNLDTFLYTVADFGPMQAKTQYDALEELEKIGFHTNREKRLCHSIDEVWSYIEEYHDK
                     RVDLPYEIDGIVIKVNEFSLQDQLGFTVKAPRWAAAYKFPPEEVETLIENIEWTVGRT
                     GVVTPTAIMTPVRVAGTTVSRASLHNGDYIKLKDIRLKDTVLIYKAGDIIPEVSQVVL
                     DKRPKDSEEYQLPTHCPVCGSELVHLDEEVALRCINPKCPAQMKEGLNHFVSRNAMNI
                     DGLGPRVLEQMYDKKLVADVADLYKLTEEELLTLDKIKEKSANNILTAIDNSKDNSVE
                     RLIFGLGIRHVGAKAAKILAEHFGDLETLSKSDYESIIALDTIGDIIADSVVTYFSNE
                     EVHELMNELKQAGVNFEYKGLRNAQLQEVESPFKEKTVVLTGKLTRFTREEAKETIEN
                     LGGKVTGSVSKKTDIVVAGEDAGSKLTKAQELGIEVWTEDQMADALAKSRSVEE"
     gene            complement(8102..10336)
                     /gene="pcrA"
                     /locus_tag="ACG8LA_000448"
     CDS             complement(8102..10336)
                     /gene="pcrA"
                     /locus_tag="ACG8LA_000448"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_process: GO:0006268 - DNA unwinding involved in DNA
                     replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HFQ0202781.1"
                     /translation="MSSKAELLNGMNPRQKEAVLHTDGPLLLMAGAGSGKTRVLTHRI
                     AYLIEEKEVNPWNILAITFTNKAAKEMKERVNAILASGGEDVWVSTFHSMCVRILRRD
                     VDFIGYNRNFTIIDSSEQLTLMKRILKELNIDPKKYDPRSILGTISQAKNSLQTPQDF
                     AKMQGSYYEEIAAKCYAAYQKELQYNQCMDFDDLIMNTIRLFEEHPDSLTYYQNKFHY
                     IHVDEYQDTNHAQYTLVNLLAGRFRNLCVVGDADQSIYGWRGADMQNILDFEKDYPDA
                     AVILLEQNYRSTKNILSAANQVIENNSNRKPKNLWTENKEGNKITYYRADNERDETRF
                     IVDRMQEEIRSNHRNYGDFAILYRTNAQSRVMEETLLKANIPYKMVGGHKFYDRKEIK
                     DILAYLNVLANPQDSISFERIVNSPKRGIGPGSIEKLRSFASLHEWPLLEAAQNVDLA
                     NIGGKAGQQLGAFGEMIQEVTQMIPYLTVTELTKEVLDRSGYLEDLKIQNTLEAQARI
                     ENLEEFLTVTQEFDKQFEQQNEEDADAPEEKLTVFLNDLALVSDIDNLEEDASQVTLM
                     TLHAAKGLEFPVVFLIGLEEGVFPLSRALMEESELEEERRLAYVGITRAEEALYLTNA
                     FSRTLYGRTQYNRPSRFVEEIDQELLEIEGMRPTPKKTPVFAKKTAYSYKQPETAVVP
                     SKSATGGENNSWKPGDKVKHKKWGLGTVVRVSGTSKDLELDVAFPSQGVKRLLAAFAP
                     IEKA"
     gene            10491..12050
                     /locus_tag="ACG8LA_000449"
     CDS             10491..12050
                     /locus_tag="ACG8LA_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClC family H(+)/Cl(-) exchange transporter"
                     /protein_id="HFQ0202782.1"
                     /translation="MEKKGKIKKLDKTQIYFILKGIFVGLLTGIVVSLFRLSIEKLSD
                     LVRSIYEMSREQPIYLIGLAICCILAAFFVGYLVKNEPDIKGSGIPQVEGQLRGELSM
                     NWFSVLWKKFIGGVLSVGAGLFLGREGPSIQLGASIGQGAGQLFRSPSSEEKILISSG
                     ASSGLAAAFNAPIAGLLFVLEEIHHSFSPLVWLTSFASAITANFVSLYFFGLRPVLYL
                     GDLPSLPLKYYGSLVILGVLLGILGFIYQKVLLALPKFYNRLPLPAYFHGFVPFLLIL
                     PIGYLWPSTLGGGNQIVLAFGHASLPIIMIIGLFVLRFVFSMISYGGGLPGGIFLPIL
                     TLGALIGSFYGNIMVDFGMDPIYIKDFVVIAMAGYFTAIGKAPLTAIILVTEMVGSLN
                     HLMPLGLAALVAYIVNDLLGGNPIYESLLERLLGNTQTASLKGARTTFDFPVTAESSL
                     DGLMVRDFNWPKNMLLISIRRGNQEILTHGDTIMNVGDILVILTDEANLPRIKQEIEA
                     KSSITNLKQSF"
     gene            complement(12161..14092)
                     /locus_tag="ACG8LA_000450"
     CDS             complement(12161..14092)
                     /locus_tag="ACG8LA_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022877 -
                     protein-N(PI)-phosphohistidine-fructose phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-specific PTS transporter subunit EIIC"
                     /protein_id="HFQ0202783.1"
                     /translation="MNIKDLMVKEAMIMDLQATDKKGAIDEMVQKMFDAGRISDIETY
                     KEGILAREAQTSTGLGDGIAMPHAKNSAVKEATVLFAKSQKGVDYEALDGQPTYLFFM
                     IAAPEGANDTHLQALAALSRLLIDADFVGKLKEANTPEEVQDLFQTAEEQKEAEEKAE
                     QETQAAEASAHPERKFVVAVTACPTGIAHTYMAEDALKKKAKEMGVEIKVETNGSEGI
                     KNRLTAEDIARAEGVIVAADKKVEMNRFDGKELINRPVSDGIRKPEELINLALSGTAP
                     VFHGDGKESSSEEGNADGTIGQRIYKDLMNGVSHMLPFVIGGGIAIALSFMIDQFIGV
                     PHDQLSNLGNYNQAASWFNQIGQAAFGFMLPVLAGFIASSIGDRPGLIVGFAAGALAN
                     TGGAGFLGALIGGFLAGYVIVFLRKLFKNLPKSLDGIKTILFYPVFGLLITGFLMLLV
                     NVPMKAINDALNGFLTSMSGSNAALLGALLAGMMAADLGGPINKAAYVFGTATLATTV
                     ATGGSVVMASVMAGGMVPPLAIFVATRLFKNKFSKTDQDAGLTNIVMGLSFVTEGSIP
                     FAAADPIRAIPSFIIGSALTGGLVGAFGIKLLAPHGGIFVVFLLSHPVMYLVFIAIGA
                     VVSGVIYGLLRKAPAAAEA"
     gene            complement(14110..15024)
                     /gene="pfkB"
                     /locus_tag="ACG8LA_000451"
     CDS             complement(14110..15024)
                     /gene="pfkB"
                     /locus_tag="ACG8LA_000451"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008662 - 1-phosphofructokinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HFQ0202784.1"
                     /translation="MIYTVTLNPSIDYIVRVDGLKLGDLNRMKEDFKLPGGKGINVSR
                     ILKRIDSQSTALGFLGGFTGEFISKWLEKEQIQSLFTTVKEDTRINIKLKSDTETEIN
                     GLGPSISDEEIDELKQALGTVGQGDIVVLSGSAPASLRKGFYQELIDIIREKGADFVI
                     DTTGDDLKNALVKKPLLIKPNNHELAELYNTTFQSVEEIIPYGKKLLAEGAQNVLISM
                     AGDGALLFTEQGTYKTNVLVRPLKNSVGAGDSMIAGFIGAYSRTKDPIEAFKWGVACG
                     SATAFSDDLAARELIDELLPEVEITKID"
     gene            complement(15021..15773)
                     /locus_tag="ACG8LA_000452"
     CDS             complement(15021..15773)
                     /locus_tag="ACG8LA_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HFQ0202785.1"
                     /translation="MLTEERRQKILDLLEQQKIVKSQDLVNLFNASESTIRRDLQELE
                     NSGFLERVHGGAKKEQLLNFEQNMSEKSLKNVHEKQQIAKSAAETINDEDVIYLDAGS
                     TTLEMIPFLQGKQITVVTNSVQHAANLVDLELATIILGGTIKLATNAVLGSNAIEQLK
                     NFHFNKAFMGMNGAHLEQGFTTPDPEEAAVKRLAMKNSEETFVLIDHTKFNQLSFTSV
                     APLEAATIITERCPLEFVNEFREKTTIKEAIQ"
     gene            complement(15932..16141)
                     /locus_tag="ACG8LA_000453"
     CDS             complement(15932..16141)
                     /locus_tag="ACG8LA_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202786.1"
                     /translation="MDKQLYYRIMVPASLLSVCLFFVPNFPIRSVIGFLVMFGGMGLY
                     YYLLHKERKPASVYMKKTRSENKKR"
     gene            complement(16152..17480)
                     /locus_tag="ACG8LA_000454"
     CDS             complement(16152..17480)
                     /locus_tag="ACG8LA_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202787.1"
                     /translation="MIGEDKLLMTIQLTDLNEEEKKQEISDWAILTRLLIQPTFIRSF
                     TQQADPYDLRKLQEKIMLASVRDESWLVVGNDENECSFRLEDNQLLIKNVLSISVFKE
                     KQFLIRDFIQKKMIAHGVFAYMRAYSEFIYHNTKQISQRLLFEKKDEIEHLPKMKQQN
                     GEVVVDCNQFPGYDLFYQGLCFTSCWEMYYSRYYHQIIPKPIFLDIQQVEKVKELENE
                     VICIQLYRDPFNWQKPNNQMFQSYFRDQLGFDHLAWDNGVGLLKPPFVEYIYTDHTIQ
                     SVQYQNAQMQPVPKKNASFFVTKSYDIQQGDYKERRVRGTLNAQAYFPWVDENRSRMM
                     CYKVIDPTVALDNGIEAYCYYIREYLEVEVTDEKYQEYLLSLRIYVPSESLSELPLKE
                     IKHRLSDVTFKRIKKKRRSIQFDVKKGEQHLRVQFLDYRELEQLITLQKI"
     gene            17616..17771
                     /locus_tag="ACG8LA_000455"
     CDS             17616..17771
                     /locus_tag="ACG8LA_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPJ_0845 family protein"
                     /protein_id="HFQ0202788.1"
                     /translation="MGLKFERTDNLDKLFESFAVDPEKTVAPKEEIDRFLKPQPQNEK
                     KKDKKQK"
     gene            complement(17845..18432)
                     /gene="yihA"
                     /locus_tag="ACG8LA_000456"
     CDS             complement(17845..18432)
                     /gene="yihA"
                     /locus_tag="ACG8LA_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTP-binding protein
                     YihA/YsxC"
                     /protein_id="HFQ0202789.1"
                     /translation="MKVHQAEIIISAVAPKQYPDTQLPEIALAGRSNVGKSSFINTLI
                     DRKNLARTSGKPGKTQTLNFYLIENALHFVDVPGYGYAKVSKTERAKWGKMIETYLTT
                     RDQLRAVVSLVDLRHKPSQEDIQMYQFLKYYDIPVIVVATKADKIPRGKWNKHESEIK
                     KALDFDRNDTFILFSSVTKQGKEEAWAAIEQAIES"
     gene            complement(18515..19765)
                     /gene="clpX"
                     /locus_tag="ACG8LA_000457"
     CDS             complement(18515..19765)
                     /gene="clpX"
                     /locus_tag="ACG8LA_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HFQ0202790.1"
                     /translation="MYDNPSSNETVRCSFCGKTQEEVKKIVAGPGVYICNECIDLCKE
                     IIDEEFYEEAVREFTEVPKPLEILEVLNNYVIGQDRAKRSLAVAVYNHYKRVNQQAQE
                     NTDDVELQKSNICLIGPTGSGKTFLAQTLAKTLNVPFAIADATSLTEAGYVGEDVENI
                     LLKLLQSADYNVERAEKGIIYIDEIDKIARKSENVSITRDVSGEGVQQALLKILEGTV
                     ASVPPQGGRKHPHQEFIQIDTTNILFIVGGAFDGIETIVKNRMGEKTIGFGTQNQKLS
                     EDESVMQHIIPEDLLKFGLIPEFIGRLPVMAALEKLTTDDLVRILTEPKNALVKQYQK
                     LLSLDNTELEFEPEALRAIAKKAIERNTGARGLRSIIEEIMMDVMFDIPSNENIEKVI
                     ITKEAAELSGEPTVIYKDSEKKAG"
     gene            complement(20012..21301)
                     /gene="tig"
                     /locus_tag="ACG8LA_000458"
     CDS             complement(20012..21301)
                     /gene="tig"
                     /locus_tag="ACG8LA_000458"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005854 - nascent polypeptide-associated
                     complex [Evidence IEA];
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA];
                     GO_process: GO:0051083 - 'de novo' cotranslational protein
                     folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HFQ0202791.1"
                     /translation="MTATFEKKGTNDGVLKFTIAQDEIQKGLTTAFNKVKKSLNVPGF
                     RKGKVSRQVFNRMYGEEALYEDALNAVLPEAYEAAVKEAGIDPVSQPKIDVESMEKGQ
                     DWVITAEVTVKPEVKLGQYKDLVVEKQDREVTDADVDARIKREQEAQAELVIKEDAAA
                     ENGDTVVIDFEGFVDGEAFDGGKGENYSLELGSGSFIPGFEDQLVGHKSGESLDVNVT
                     FPEDYQAEDLAGKEAVFKVTIHEVKAKEVPELDDEFAKDVDDEVSTLDELKEKYRKEL
                     VETKEKAADDAKDEAAIRMAVENAEIVELPHVMVHDEVHRSMDEFLNNMQRQGISPEM
                     YYQLTGSTEEDLHKQFEGEAEMRTRTNLVIEAIAAAENLQATEEEINAEIQELSETYN
                     MPIEQIKRVLTEDMLEHDVTMKKAIELITGTATEAKE"
     gene            complement(21455..22387)
                     /locus_tag="ACG8LA_000459"
     CDS             complement(21455..22387)
                     /locus_tag="ACG8LA_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202792.1"
                     /translation="MKPIDFPEKYENLMRVAQQALANQQYQQAKELFQRAYELKESFE
                     ANSLLVFCLYELDEKKEALKQALLHEKQYLQNEEFAEFYFDLLISTQDFLYARKLIAS
                     TDFYEAFEQRVIEKIQFAEELSGQMERQKIKALHNKSEELPSLEPARQLASIDEIEQL
                     PYHEFIQTASKLIVSPEVHILARAKLLETLRQLNECHPVFYLTIEEKLVKVIPKDLPK
                     PQQQASYQQLCVFSDRYGNEDALLSSVLNEEFTLQSAIVYPVYDTYIEDPKRWFQLTV
                     EACTGKTMYEGTEDEKQDFLKKREKILQQMIFFH"
     gene            complement(22544..23203)
                     /locus_tag="ACG8LA_000460"
     CDS             complement(22544..23203)
                     /locus_tag="ACG8LA_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HFQ0202793.1"
                     /translation="MSELSNENKEQEKDKQQQPAVGPDSNFSQKVLSSFEREPLTPEE
                     IKKKQRKWKKYTDTRNEPPKANDFPKYFYAGFFIRMFAFLVDLLCIGAITRLTLGIAK
                     NLGWLNFSDSYLSIYGFTALLIYLAYFILLTKFNHGQTIGKMIFGIRVISFDEEELSW
                     STVLVREGACRFILKFPLLMLGYLPAIFNQKKQHLGDFFTNTSVVTINLIKAFNQEVN
                     S"
     gene            complement(23206..24231)
                     /gene="sppA"
                     /locus_tag="ACG8LA_000461"
     CDS             complement(23206..24231)
                     /gene="sppA"
                     /locus_tag="ACG8LA_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HFQ0202794.1"
                     /translation="MNKRRWAAVLIAAGLFVVSLVSASLTKPQENDQIEGLNSWLYGD
                     EELASNVLEEGDSTQKIVKLSVDGTIAAGGSSGLFASEGYNHKNFMEQLKAIEEDPTV
                     KGIFLEVNSPGGGVYESAEIAKKLDTIRKEHDIPMYVSMKNMAASGGYYISAQADKIF
                     ATEETVTGSIGVIMSGLNYSGLLEKLGVEDTTVKSGALKDMGSGTRPETKEEEAVLQA
                     YIDSAYSRFVAIVSEGRNKSEEEVKKIADGRIYDGVQAKEVGLVDELGFPEDALKAMR
                     KEQQLEDAELVEYSSTPSGFASTWLGSKLAEFQGLKPSETSQILSVLENLGTAESPKA
                     MYYYGGE"
     gene            complement(24244..24534)
                     /locus_tag="ACG8LA_000462"
     CDS             complement(24244..24534)
                     /locus_tag="ACG8LA_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202795.1"
                     /translation="MDSKIEIMTLGMLKKQLSKFEASAGVSDDTKIFLDTGWDSIQEI
                     APDALEVAEAREFTVEDELTKESFSGYAREEKAERFDTSEQSETVIVIKNLY"
     gene            24944..26749
                     /gene="glmS"
                     /locus_tag="ACG8LA_000463"
     CDS             24944..26749
                     /gene="glmS"
                     /locus_tag="ACG8LA_000463"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004360 - glutamine-fructose-6-phosphate
                     transaminase (isomerizing) activity [Evidence IEA];
                     GO_process: GO:1901137 - carbohydrate derivative
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HFQ0202796.1"
                     /translation="MCGIVGMIGLKNVTPGLIDGLEKLEYRGYDSAGIFVSDGTTDYL
                     VKAQGRIQNLKNKINIDTTGNIGIGHTRWATHGQPSEENAHPHTSQSGRFVLVHNGVI
                     ENFEELKIAYLANDHFIGETDTEIIAHLIETFAKDTTTQEAFLKALRVIKGSYAFALI
                     DRTAPDVIYVAKNKSPLLIGLGDGFNVIASDAMAMLAHTKEFVEIEDEEMVTVTSEKV
                     IIQNFAGDIVERSSFEAQVDSSDIEKGTYPFYMLKEIDEQPIIMRRIAQKYVTEDNRV
                     SLDQKLVDTLSDSDRIYIVACGTSYHAGLAGKQTLEKLTQIPVEVHLASEFGYNTPLL
                     SKKPFFIFLSQSGETADSRQVLVKINRLGYPSLTITNVAGSTLSREASFTLLLHAGPE
                     IAVASTKAYTAQIAVLTLLAKAIGDKKEFETSLVFDITHELSLVANAMESVIAQKDYL
                     EELAEVYLSDTRNAFYIGRGADYNVSLEAALKLKEISYIQAEGFAAGELKHGTIALIE
                     EGTPVIGIISEEVTGAHTRGNLKEVESRGAKTLVIVSEGLEKESDQLVLPTVHPYLTT
                     LTTVVPTQLLAYYATLLRGFDVDKPRNLAKSVTVE"
     gene            complement(26821..28176)
                     /gene="glmM"
                     /locus_tag="ACG8LA_000464"
     CDS             complement(26821..28176)
                     /gene="glmM"
                     /locus_tag="ACG8LA_000464"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010739004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008966 - phosphoglucosamine mutase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HFQ0202797.1"
                     /translation="MGKYFGTDGVRGEANKELTPELAFKLGRCGGYVLSQHEEEGKRP
                     RVLVGRDTRISGQMLEEALISGLLSVGIEVFQLGVISTPGVAYLTRLQKASAGVMISA
                     SHNPAQDNGIKFFGADGFKLVDDQELEIEALLDAEVDELPRPSAEGLGTVEEFPEGLL
                     KYSQFLVQTINGDLSGLTICVDAANGATSTSVNRLFADLETDFYTMGTNPDGLNINDG
                     VGSTHPERLAEMVVEKGADAGLAFDGDGDRIIAVDELGNIVDGDKIMFICAKYLAEKN
                     RLKKDTIVTTVMSNLGFHKAVEGIGLKDVVTQVGDRYVVEEMRKNDYNFGGEQSGHMI
                     FLDFNTTGDGMLSGIQLLNIMKQTGKKLSELAAEVTIYPQKLVNIRVSDKNGAMDVPA
                     IKKVIEEAEAEMGSEGRILVRPSGTEPLLRVMAEAPTDEKVNYYVDKIAAVVKEEIGL
                     D"
     gene            complement(28200..29369)
                     /locus_tag="ACG8LA_000465"
     CDS             complement(28200..29369)
                     /locus_tag="ACG8LA_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CdaR family protein"
                     /protein_id="HFQ0202798.1"
                     /translation="MISKEKRTSILYSFIALLFSIALYFNANGQSVPNTLSGNEAYNQ
                     TVTGVPIKISYDSKRYYIHGYENAVTVKLSSANRVQLNAEANEDTRMFRVTADITKLG
                     EGTHEVPLKIQNLSSAVTAKIEPSTITVTVEKKVIKDFDVETLIPSTFTPSGYELDDT
                     SVSPKKVSITTGDKTLAEIKRVVADVDASMVTDDGINSEVPIQALNAAGEVLSIVSDP
                     VQVTVRADSIKPSKSVRLYGIQQGTPAAGVESYDFSFSKLEAEVSGSSDLLASIGDSI
                     AVPINVSGINHRTTRKIEIPVEEGLSIKPESVSVEITPVLQTSSSSSASTSSRTQENT
                     STSRSISSADSGTEPSTTTISSSSESGTSSSTTSTEETSETSESTQMSRTNSSEN"
     gene            complement(29366..30253)
                     /gene="cdaA"
                     /locus_tag="ACG8LA_000466"
     CDS             complement(29366..30253)
                     /gene="cdaA"
                     /locus_tag="ACG8LA_000466"
                     /EC_number="2.7.7.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004016 - adenylate cyclase activity
                     [Evidence IEA];
                     GO_process: GO:0006171 - cAMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diadenylate cyclase CdaA"
                     /protein_id="HFQ0202799.1"
                     /translation="MSFQIGELFNLDYWQQMFSGDLFSLNFLVNILDILVVWYLVYKL
                     IQLLRGTKAIQLLKGVAIFIVIRIVAEIIGLHTLSWLMNQVITYGVIAAIVIFQPEIR
                     RGLEHLGRSSLFKQSKSEQQEDEKMILSFDKAIQYMSKRKIGALITIERHTGLDEYIE
                     TGIALDADITGELLINIFIPNTPLHDGAVIVKEGKIAVASAYLPLSESMLIPKEFGTR
                     HRAAVGISEVSDAITIVVSEETGDVSITLDNELMAGLSQQEYLAILRRELIAEEKTKN
                     KKNVIQSFLDGMTKGGDRK"
     gene            complement(30442..34122)
                     /gene="nifJ"
                     /locus_tag="ACG8LA_000467"
     CDS             complement(30442..34122)
                     /gene="nifJ"
                     /locus_tag="ACG8LA_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0016903 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors [Evidence IEA];
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA];
                     GO_process: GO:0022900 - electron transport chain
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HFQ0202800.1"
                     /translation="MRKMKTMDGNTAAAYISYAFTEIAAIYPITPSSTMAELVDQWSA
                     AGKENVFGQPVKVVEMQSEAGAAGVVHGSLKTGALTTTYTASQGLLLMIPNMYKIAGE
                     LLPSVFHVASRAVTTNALNIFGDHGDVMAARQTGFAMLAESSVQEVMDLAPVAHLASI
                     EGEVPFLNFFDGFRTSHEIQKIEVLEYEELAPLINQEKLASFRKRGMNPNHPTVSGTN
                     QNPDIHFQQRETINPYYDKLPEIVQKYMKEINRLRGTSYDLVTYYGADDAEEVIVSMG
                     SVAQTIEQTIDYLNANGRKTGFLNIHLYRPFPVETFVQKLPHTVKTIAVLDRSKEPGA
                     GGEPLLLDVQSALYDSELRPAVIGGRYGLGSKDVTPDQISAVFDELKKDPSIRKKRFT
                     IGIVDDVTYQSLEPKESLDLTEPQTFQAKFWGFGSDGTVGANKSAIKIIGDHTDKYAQ
                     GYFYYDSKKSGGLTVSHLRFGDTPIRSAYLVEHADLVACHTPAYLHSYDLVKGLKPGG
                     IFLLNTLWSDEQLETHLPLKLKRYLAENNIRFYTINAMRLAQEVGLGRRINTAMETAF
                     FKLADIIPFDEVLPLLKEEALKSYGHKSMTIVEKNIQAIDRTTELLHQVAIPDHWRTL
                     EMPEKINKRNTGYIQEILEPVNAQEGNQLSVGTLVANGMTTGEMPLGTASMEKRGVAL
                     EVPEWISDRCTMCNECAFVCPHAAIRPFLADEEEMEEAPEGFIVREMRGADGVKYRIQ
                     VSVEDCTGCGLCVEACPAKEKALVMKPYEEQKEQAVNWAFAMTLRQKANPVKGKNTVL
                     STQFNQPLLEFSGACSGCGETPYVKLLTQMFGDRMMIANATGCSSIWGGASPASPYTT
                     NECGQGPAWSNSLLEDNAEFGYGMLLAAQTRREALASSIKEVLPKVSEELRELMEDWL
                     VHMFESEGTQQRAAKLQAAIESERSIVPELEDIYKRKDLFVKNSQWMIGGDGWAYDIG
                     FGGIDHVLASGADVNILVLDNEVYSNTGGQTSKATPASAIAKFSASGKYASKKDLGMM
                     AMTYGNVYVAQIASGANQMQTIKAFEEAEKYPGPSLIIAYTPCITHGLLGGMKESLKE
                     AKEAVSSGYWSLYRYNPAMVEKNKNPMTLDYKKPDFSAMPDFMRKQVRFSSLENANPN
                     LAKALFEKTIQDAKTRFYNYAALTGELEKIKKRLEPEESIDVPVKTRKEKTTDLEAEE
                     RRAARAERRKKMEQATKEKKEK"
     gene            34320..34841
                     /locus_tag="ACG8LA_000468"
     CDS             34320..34841
                     /locus_tag="ACG8LA_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015036 - disulfide oxidoreductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HFQ0202801.1"
                     /translation="MDISVIDATKTNTQKGILYGSSNAPKKMVEFINLSCPYCRQWFE
                     ESYELLEEAVQSGQLQRVIKLFDKEKESLQRGNVMHRYLTISDGQKAIKEIKQIFDTQ
                     DEWKHLSLQEVADFAVDKLKLTEQKDEQLSQAVINEAEQAHIRFVPTVILGKEIFDES
                     ISIEELKELIQTK"
     gene            complement(35540..36105)
                     /locus_tag="ACG8LA_000469"
                     /pseudo
     CDS             complement(35540..36105)
                     /locus_tag="ACG8LA_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294436.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(36284..36940)
                     /locus_tag="ACG8LA_000470"
     CDS             complement(36284..36940)
                     /locus_tag="ACG8LA_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202802.1"
                     /translation="MRFFTTFTIIMIAVLFIFLDIAKRNTAFLLYRVLLRAGLITFIS
                     IVGFFLFTVIVFIWRTPAPPLPEITYGEFPFRLEYELNEELHVIEDTLIVEFDGFGMN
                     EGIGRYRRWTSRLASGEDLVLLLEVSDNKQIFYFPGPANYYMGDRLNGYNHTFPSASF
                     IERERGITRRDILHDKELLEQFGPLDQNTINEEELLNQYNIRLVNWEISEPIVNNFGD
                     "
     gene            complement(37508..38443)
                     /gene="whiA"
                     /locus_tag="ACG8LA_000471"
     CDS             complement(37508..38443)
                     /gene="whiA"
                     /locus_tag="ACG8LA_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0043937 - regulation of sporulation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HFQ0202803.1"
                     /translation="MSFAADVKKELTGLEVHREHAKAELAALLRMNGSLGIVNQQFIL
                     NVQTENAAIARRIYSLLKDHYQVRSELLVRKKMKLKKNNVYIVRLKQGTKDVLMDLDI
                     MDGMMFNGHVSDEIMGNSQKMRSYLRGAFMASGSVNNPETSRYHLEIFSIYEQHNQDI
                     CDMLNYYGLHARTLERRNGYISYLKGAEKIADFLTLIGATNSMLRFEDVRIVRDMRNS
                     VNRLVNCETANLNKTIDAASKQIENIELIEAKVGLHALPEKLQEIAELRLQHPEVSLK
                     ELGEMIPSGAISKSGINHRIRKINEFAEKLREEAV"
     gene            complement(38477..39475)
                     /gene="yvcK"
                     /locus_tag="ACG8LA_000472"
     CDS             complement(38477..39475)
                     /gene="yvcK"
                     /locus_tag="ACG8LA_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine diphosphate-N-acetylglucosamine-binding
                     protein YvcK"
                     /protein_id="HFQ0202804.1"
                     /translation="MKMKTYRIRKPKIVVVGGGTGLPVILKSLRNQGADITAVVTVAD
                     DGGSSGAIRESIAMAPPGDLRNVLVALSDMPQFYEDIFQYRFKKEDQFLANHTIGNLI
                     IAAVSEMRGSTYEAIQLLAKMMHVDGHVYPSSETPLTLHAVFKDGTTAVGESKIAIDR
                     KTIDRVYVCNTNDKSEAKAARKVVSAIMDADMVVLGPGSLFTSILPNLVIPEIGEAML
                     KTTAETVYICNIMTQKGETEHFTDADHIRVLHKHLNQPFIDTVLVNTEKVPEDYMDPE
                     IYDEYLVQVAHDFNGLRNEGCRVISTDFLELKDGGVFHDGDKVVEELFRLVFGSKY"
     gene            complement(39472..40356)
                     /gene="rapZ"
                     /locus_tag="ACG8LA_000473"
     CDS             complement(39472..40356)
                     /gene="rapZ"
                     /locus_tag="ACG8LA_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HFQ0202805.1"
                     /translation="MTDNLQLVIITGMSGAGKTVAIQSFEDMGYFCIDNMPPRLIPKF
                     WELIKESGKVTKMALGVDLRSRSFFEEIQNMLIEIENTNFIDTSILFLDASDEELVAR
                     YKETRRAHPMAMDGLITEGIRKERAILDDLKAQASVIIDTTTLTPRQLREKINESFKS
                     KGDQGFRIEFVSFGFKYGLPIDSDIVMDVRFLPNPHYIPELRPLTGKDQPVYDYVMSF
                     DETQSFYHKFLDLLETVLPGYIKEGKSSLTVAIGCTGGQHRSVALTERLANALGKNYK
                     VNVTHRDKDKRKETVNRS"
     gene            complement(40491..41222)
                     /locus_tag="ACG8LA_000474"
     CDS             complement(40491..41222)
                     /locus_tag="ACG8LA_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate racemase"
                     /protein_id="HFQ0202806.1"
                     /translation="MENFFSILGGMGTMATESFVRLINHRTKATKDQEYLNYVLFNHA
                     TVPDRTAYILDRSEENPMPFLLDDIEKQNLLQPNFIVLTCNTAHYFFEELQAATDIPI
                     LHMPREAANELVRQHTTGRVAILGTEGSMKAGIYEREVKNLGFETVIPDTVLQEKINY
                     LIYHEIKESDYLNQELYYEILEEAVERLNCEKVILGCTELSLMHEFAEDNHYPVIDAQ
                     SILADRTIERALAERSKALDTASEK"
     gene            complement(41226..42491)
                     /locus_tag="ACG8LA_000475"
     CDS             complement(41226..42491)
                     /locus_tag="ACG8LA_000475"
                     /EC_number="6.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aspartate ligase"
                     /protein_id="HFQ0202807.1"
                     /translation="MMNSIENEEFIPILLGSDMNVYGMARSFNEAYGKICQAYASDQL
                     APTRYSKIVNVEVIPGFDKDPVFIETMLRLAKERYSDKSKKYLLIACGDGYAELISQH
                     KQELSEYFICPYIDYSLFERLINKVSFYEVCEEYDLPYPKTLIVREEMLVNGHLEQEL
                     PFEFPVALKPANSVEYLSVQFEGRKKAFILETREEFDLILGRIYEAGYKSEMIVQDFI
                     PGDDSNMRVLNAYVDEDHQVRMMCLGHPLLEDPTPASIGNYVVIMPDYNEKIYQTIKA
                     FLEKIEYTGFANFDMKYDPRDGEYKLFEINLRQGRSSFFVTLNGLNLARFVTEDRVFN
                     KPFVETTYGTNQSDKARLWMGVPKKIFLEYARENEDKKLAEQMIKENRYGTTVFYEKD
                     RSIKRWLLMKYMFHNYIPRFKKYFHVKEG"
     gene            complement(42754..45570)
                     /gene="uvrA"
                     /locus_tag="ACG8LA_000476"
     CDS             complement(42754..45570)
                     /gene="uvrA"
                     /locus_tag="ACG8LA_000476"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HFQ0202808.1"
                     /translation="MANDKITIHGARAHNLKNIDVTIPRDKFVVVTGLSGSGKSSLAF
                     DTLYAEGQRRYVESLSAYARQFLGQMDKPDVDSIDGLSPAISIDQKTTSKNPRSTVGT
                     VTEINDYLRLLFARVGHPICPNDHIEITSQSVDQMADQVMALPERTKIQVLAPIVVKK
                     KGQHKKIFERIQKEGYVRVRVDGEIYDLSEVPELEKNKKHDIAIVIDRIIVKEGIRSR
                     LFDSLEAALRLADGYALVDVIGEEEMLFSEHYACPYCGFTVGELEPRLFSFNAPFGAC
                     PDCDGLGVKLEVDQDLVIPDRTKTLSQGAIVPWNPISSQYYPQMLAQACESFGIDLDT
                     PFEELPEEHQDIILNGTDDLFHFHYENDFGGVRDVETTFEGVLKNIERRYHDTNSDFT
                     REQMRLYMTELTCQTCKGYRLNPQALSVQINGTNIGQTNELSIQKAVDFFSNLTLSEQ
                     EKVIAKPILKEVNDRLSFLENVGLDYLTLSRASGTLSGGEAQRIRLATQIGSNLSGVL
                     YILDEPSIGLHQRDNDRLIGSLKKMRDLGNTLVVVEHDEDTMWAADYLIDVGPGAGEQ
                     GGQIVAAGTPEEVANDENSLTGKYLSGKKSIPVPKERRKGNGKAIKITGASENNLKNI
                     SVEFPLGEFVAVTGVSGSGKSTLVNSILKKSLAQKLNKNSAKPGKFKTISGYESIEKI
                     IDIDQSPIGRTPRSNPATYTSVFDDIRGLFAQTNEAKMRGYKKGRFSFNVKGGRCEAC
                     RGDGIIKIEMHFLPDVYVPCEVCHGKRYNSETLEVHYKGKSIADILEMTVEDAVEFFK
                     HIPKIHRKLQTIVDVGLGYVTMGQPATTLSGGEAQRMKLASELHKISNGKNFYILDEP
                     TTGLHSDDIARLLHVLQRLVDAGNTVLVIEHNLDVIKTADYIIDLGPEGGEGGGTILA
                     TGTPEEIINVKESYTGHYLKKIMV"
     gene            complement(45580..47574)
                     /gene="uvrB"
                     /locus_tag="ACG8LA_000477"
     CDS             complement(45580..47574)
                     /gene="uvrB"
                     /locus_tag="ACG8LA_000477"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009380 - excinuclease repair complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HFQ0202809.1"
                     /translation="MIERDTSRHFELVSKYQPAGDQPEAINQLVDGVVGGKKAQILLG
                     ATGTGKTYTISNLIEKVNKPTLIIAHNKTLAGQLYGEFKEFFPNNAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVIASVSCIFGLGSPFEYQ
                     KQVVSIRQGAELDRNQLIRDLVSIQFERNDIDFQRGRFRVRGDVVEIFPASRDERALR
                     VEFFGDEVERIREVNALTGEVLGETEHVAIFPATHFVTNDEHMEHAVANIKAELEQRL
                     TVLRNENKLLEAQRLEQRTNYDIEMMLEMGYTSGIENYSRHMDGRKEGEPPYTLLDFF
                     PEDFLIVADESHVTMPQVRGMYNGDRARKQMLVDYGFRLPSALDNRPLRLEEFEKHVN
                     QIIYVSATPGPYEHEQTDTVIQQIIRPTGLLDPVIEVRPIMGQIDDLVGEINERVEKD
                     QRVFVTTLTKKMAEDLTDYFKELGIKVKYLHSDIKTLERTEIIRDLRLGEFDVLVGIN
                     LLREGLDVPEVSLVAILDADKEGFLRSERSLVQTIGRAARNEEGKVIMYADKVTDSMR
                     LAMDETSRRRTIQQKYNEEHGIVPKTIIKEIRDLISITKESEDDTKEAVQVSYEEMTK
                     EEKDTLLMKLEKEMKNAAKALDFETAANVRDMILELKASK"
     gene            47833..49335
                     /locus_tag="ACG8LA_000478"
     CDS             47833..49335
                     /locus_tag="ACG8LA_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HFQ0202810.1"
                     /translation="MKRKHLFHSFVFLMTGLVTLAFGHVAQADNTTTAESSTSETMQK
                     IEPKKDVYVIASDSAFAPFEFQNAKGEYEGIDVKLMENIAKLQGFNIRMDYRGFSAAL
                     QALESGQADGMIAGMTVTDERKKSYDFSDSYFDSGIQLAVKKGDTSIKSYEDLKGKTV
                     GAKVGTESAEFLSDHESEYGYSIKYFDAADQLYDGLKVGAIDAMMDDYPVIGYAIKQG
                     QELETPIKKESGGKYAFAVKKGQNPELLNMFNEGLKELKRTGEYDKIIKEYVADGSET
                     SSESSTADESTFLGLIQNNYQALLKGLWRTILLTLISFALAIVIGVIFGLFSVAPIRA
                     LRTIASIYVDIIRGIPMMVLAFFIFFGLPGIVGFTIPDFLAGVITLTLNASAYIAEIV
                     RGGINAVPVGQMEASRSLGLSYNRTMQKIILPQAIRIMIPSFVNQFVISLKDTTIISA
                     IGVVELLQTGKIIVARTTQSTYVYLIIAIMYLILITALTKLAKVLEKKVK"
     gene            49337..50074
                     /locus_tag="ACG8LA_000479"
     CDS             49337..50074
                     /locus_tag="ACG8LA_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010760672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HFQ0202811.1"
                     /translation="MAEKILVEHLVKKYGDNTVLNDINVSINEGDVVCIIGPSGSGKS
                     TFLRCLNRLEEPSDGEIIIDGAHLMDKSTDINLVRQHIGMVFQHFNLFPHLSILENII
                     LAPMDLKKESREEAEKKAIKLLQTVGLEDKKDMYPEMLSGGQKQRVAIARALAMNPDI
                     MLFDEPTSALDPEMVGDVLNVMKKLAEQGMTMVIVTHEMGFAKEVANRVMFIDDGNFL
                     EDGTPQQIFENPQNERTKDFLNKVLNI"
     gene            complement(50442..51608)
                     /gene="dnaJ"
                     /locus_tag="ACG8LA_000480"
     CDS             complement(50442..51608)
                     /gene="dnaJ"
                     /locus_tag="ACG8LA_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HFQ0202812.1"
                     /translation="MATKRDYYEVLGLSKGASEDEIKKAYRKLSKKYHPDINKEPDAE
                     EKFKEVSEAYEILSDPQKRAAYDQYGHAGTDPNYGAGGAGGGFGGFGGFSGGGFGGFE
                     DIFDSFFGGGGRSVDPNAPRQGADLQYTVDLSFEEAIFGVEKEIKYNREEICHTCGGN
                     GAKPGTQPTTCHKCHGAGTINVERQTPLGRVMSRQTCDVCHGTGKEIKEPCPTCHGSG
                     HEKKAHSVKVNVPAGVEEGQQMRLAGQGEAGENGGPFGDLYVVFRVEESDIFDREGSE
                     IYYELPLSFVQAALGDEVQVPTVHGDVKLKIPAGTQTGTNFRLRGKGAPKLRGGATGD
                     QHVKVKLITPKNLNEQQREALRAFAEAGGIKVEEQQEDGFFDKFKDAFGGKKRK"
     gene            complement(51759..53588)
                     /gene="dnaK"
                     /locus_tag="ACG8LA_000481"
     CDS             complement(51759..53588)
                     /gene="dnaK"
                     /locus_tag="ACG8LA_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016635026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HFQ0202813.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGNEAKIIANPEGNRTTPSVVSFKN
                     GEIQVGEVAKRQAVTNPNTISSIKRHIGEAGYKVDVEGKSYTPQEISAMILQYIKGFA
                     EDYLGEKVEKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTD
                     RDEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNHLGGDDFDNKIIDYMVAEFKKE
                     NSIDLSQDKMALQRLKDAAEKAKKDLSGVSSTQISLPFITAGESGPLHLEMTLTRAKF
                     DELTADLVERTKVPVRQALKDAGLSQSEIDEVILVGGSTRIPAVVEAVRKETGKEPNK
                     SVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTS
                     KSQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDID
                     KNGIVNVSAKDLGTQKEQKITIKSSSGLTDEEIERMVKDAEANAEADKARKEEVDLRN
                     DVDALLFSVDKTLKELEGKVDEEEVKKAETARDELKAAVEANNIEEMKTKRDALNEIV
                     QNLTVKLYEQAAQQQAQENPEAAQGGADDVVDADFEEVDGDDK"
     gene            complement(53639..54202)
                     /gene="grpE"
                     /locus_tag="ACG8LA_000482"
     CDS             complement(53639..54202)
                     /gene="grpE"
                     /locus_tag="ACG8LA_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HFQ0202814.1"
                     /translation="MKENQEELDKEMTDAQPEPEIDVEAAEDSGISEAEAEEFETAKL
                     KAELEEMEDKYLRARAEIANMANRGKNEREQLQKYRSQDLAKKLLPSIDNLERALATE
                     VSDDQGAGLKKGVEMVLESLRNALEEEGIEKIPAKGEAFDPNLHQAVQTVPATEDTPA
                     DTIVEVLQEGYKLHDRVLRPTMVIVAQ"
     gene            complement(54296..55339)
                     /gene="hrcA"
                     /locus_tag="ACG8LA_000483"
     CDS             complement(54296..55339)
                     /gene="hrcA"
                     /locus_tag="ACG8LA_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HFQ0202815.1"
                     /translation="MLTKRQNDILRLIIQHYTSSGVPVGSKTLMSEGVKASSATIRND
                     MKALEDEGLLLKTHSSSGRIPSALGYRYYVDHLLKPARVAEDDLLLIRQSLGREFHEI
                     NEIIKQSAEILSELTSYTTFSLGPEIKDRRLTGFRIVPLNNRQIIAIVVTDMGNVESQ
                     VFTLPEYMGSQELEKMVQIVNDRLVGDPLMTVYHKLRTEIPMILHKYFQTTEGMSQLF
                     DTVLGHVFEEKVYVSGQMNLLDYEPRQDLDQFKSMFSFMKDSDGLTQMITPMDSNIHI
                     KIGAELGNDLLQNMSMIQASYEIDGHGRGTIALLGPTSMPYSRMFGLVDVYRRELAAK
                     LADYYRSLDLSNS"
     gene            complement(55574..56740)
                     /gene="hemW"
                     /locus_tag="ACG8LA_000484"
     CDS             complement(55574..56740)
                     /gene="hemW"
                     /locus_tag="ACG8LA_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0051989 - coproporphyrinogen dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM family heme chaperone HemW"
                     /protein_id="HFQ0202816.1"
                     /translation="MIETINPAENKVSAYIHIPFCEHICYYCDFNKVFLEGQPVDEYV
                     EMLLNEMRLMLESHPTANLETLYVGGGTPTSLSAKQLDRLLSGAREILPFQNGNEFTV
                     EANPGDLTREKLQVMKNYGVNRLSMGVQTFDNRLLKKIGRKHTAEDVYQTMQFLEAEN
                     FTNVSIDLIYALPGQTLEGYRDTLEKALALDLPHYSLYSLILENKTMFMNWVRQGRLE
                     LPDQETETRMFEETIEAMEKHGRHQYEISNFGLSGHESQHNLMYWNNDHYFGFGAGAS
                     GYLGDIRYRNKGPIQHYLRPLRANERPVLEEEKLTRKNQIEEEMFLGLRKKTGITKKH
                     FYDRYQKTIESVYGDVLRELEQEGLLVNEEDRVYLTPRGTFLGNNVFERFLFEK"
     gene            complement(56756..56983)
                     /locus_tag="ACG8LA_000485"
     CDS             complement(56756..56983)
                     /locus_tag="ACG8LA_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HFQ0202817.1"
                     /translation="MKIAFHIFADFDLMPKVSFAITVYREAVKAPCSSDDNKQAFLEL
                     GFLDSKYAAYFNELVLERDFKKVENRHDFST"
     gene            complement(57303..57626)
                     /gene="relB"
                     /locus_tag="ACG8LA_000486"
     CDS             complement(57303..57626)
                     /gene="relB"
                     /locus_tag="ACG8LA_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB family
                     antitoxin"
                     /protein_id="HFQ0202818.1"
                     /translation="MRFFKRGNYRAMITVRVSDAKKEWLSYMAEFYGITLSELLKNYS
                     MEQLEDEYNRQTAEIAHKHWIRSGKTTVFMEESLMNLVGWNDLPFKIHARNSEAALIG
                     KYVYW"
     gene            complement(57969..58415)
                     /locus_tag="ACG8LA_000487"
     CDS             complement(57969..58415)
                     /locus_tag="ACG8LA_000487"
                     /inference="COORDINATES: protein motif:HMM:NF013964.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HFQ0202819.1"
                     /translation="MKIKIYNQEENQTRHIRNLSNAKLEEEARKVSNYNKKMAAKYVN
                     EEEFCFSKTKIYKRNPFVSEYVKRLAKGICQLCQEKGPFIKDGVPYLHCHHIEYLSQG
                     GKDVIENCIALCPNCHARIHELELPDDKEKLLKIVEKRENSFSKIP"
     gene            complement(58396..58992)
                     /locus_tag="ACG8LA_000488"
     CDS             complement(58396..58992)
                     /locus_tag="ACG8LA_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HFQ0202820.1"
                     /translation="MNPTLITKKELLKKLDISTGVLANLIRNGMPKEGEMFNLDKIIT
                     WRENWSKNILGELEVGRVYTNKEISEKFKCSKQGGMRRSHQTNTLVLFSDQTGSNVYK
                     DKWLNGILQYTGMGLKGDQVLDKNQNKVLANSKSNFVKIHLFETFKPKEHTYLGEVYL
                     AGQIYTVNEKDSSGNSRKVYKFPLALINQEQLIEDKDI"
     gene            complement(59476..59637)
                     /locus_tag="ACG8LA_000489"
     CDS             complement(59476..59637)
                     /locus_tag="ACG8LA_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202821.1"
                     /translation="MTEKEQVQQIVKKYNKSIADLSENASAKEFKTVMNYVADEANRK
                     QRKLVGLDK"
     gene            complement(59630..60304)
                     /locus_tag="ACG8LA_000490"
                     /pseudo
     CDS             complement(59630..60304)
                     /locus_tag="ACG8LA_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297358.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
     gene            60827..61434
                     /locus_tag="ACG8LA_000491"
                     /pseudo
     CDS             60827..61434
                     /locus_tag="ACG8LA_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313657.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0019172 - glyoxalase III activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase family
                     protein"
BASE COUNT        17125 a        13256 c        10689 g        20659 t
ORIGIN      
        1 taaaaagact aagaaacaat aacaaaagtt aacacttctt agtctttctt tagcacgtct
       61 atttattaaa gattttaggg ccttttctca tgtttttacg atcattctta ggtgtttcca
      121 tttgtttgga tcggcctcca ccttgtttct ttttgatcaa ttctttcatt ttttcttttt
      181 ggtccatttt tattctcctt taacgaatga agcgactaat tcgatatgat gggtttgcgg
      241 gaaaagatct acaggctgaa ctttcttcac ggcataacct gcttctgcaa ataacttagc
      301 atctcttgca aaagttgccg gattacatga gatatagacg attcgttctg gtgacatttc
      361 gattgctgat tcaataaaat gatgatctaa tccttttcgt ggagggtcaa ctacgatcac
      421 agatggtttg atcccttttt cttgccattt tttcataact ttttctgctt ttccgacttc
      481 ataatgaaca ttttcgattt tattatttaa agcattgaac tgtgcatctt caattgcttc
      541 tggaataact tccatcccat acaccttatc cactctgtct gctaaagaca agccaatcgt
      601 acctattcct gaataagcgt cgatcacaat gtctttttta tctaactcgg caaactcgat
      661 ggctgtttgg tacagatact ctgcttgttg agtatttact tgataaaatg actttgctga
      721 gattcgatag gtttttccta atagctgatc ttcgatatag tctctgccat ataaaacttt
      781 ttctttgtct cctaaaatca catttgtttt ttcttcattg atattttgga tgaccgaaac
      841 cacttctggc aattcttcat gaatagcttc agcaatttcc ttggatttaa agaatttttc
      901 tttacgagta actaaaacga ccatcatttc atgggaataa tgaccacgac ggataatgat
      961 gtgacgaagc tgtccttcat ttttttcttc attatatcct cgtacttgga accgttgcaa
     1021 gatatctctg actactttga ttgcttgatc gatgacagga tcttggatat aaaaatcttc
     1081 gatagggact agatcatggc tattcttttt gtaaaaaccg gtggctaact gtccatcgat
     1141 acggcgaaca gggatctgtg ctttattacg gtagccgaat ggttctgcca ttccgaccgt
     1201 tggaagtaca ggaacttctg gcatcttagc aatcttcgcc attacatgct ctacttgttt
     1261 ttgtttgaag acaagctgtt gttcatactt caaatgggct aaaggtgcga tacctatgcg
     1321 aagtaatgca ttgttttcta caggctgacg atcaggtgat tgtgtaataa atgtttcgac
     1381 ttttccatat ccaaacttat tgcctgcttt tactactagt atttctactt cttctccagg
     1441 gagtgcattt tcgataaata atggataacc atcgattttt gctaccccca ttccttcata
     1501 actcaagtcg acgatttcga ctgtatatcg ttcgtttttc tttactattt gctgttctgt
     1561 catattttgc tcctttaagc ctatttttca atcctactga actctactat aaatcagcta
     1621 attacacaac taaaaccggc actgacctta ctacgttcag caccggcttt tgattaattc
     1681 ttttgattag gtgtttcgtc tgctattttt ccgtcaccgt cgatatcttc atccgttaaa
     1741 cgttcgactt cttttacgaa ttctttgctg acaacctcta attcttcttc atctgtacct
     1801 gtgattgctt catcaggaat ctgatcggta ttggcaaaga actcaatgtg ttgatgaaga
     1861 ttttggaaat gcatcggtgc ttccccgccg tattcaccat ctaagttgat cattactggt
     1921 cgattgatat catcttctgt ttcaacgaac aaactgcttg ttttggtata gattattctt
     1981 ggatcatcga catgtcgacc gccattcagc atgagtgctg caatatgcaa gatctcaaag
     2041 atatttgctg tcttcacaat gattaaagaa aacttcccat catccaattt ggcatctggc
     2101 gcgatctgtt cgaatcctcc aacagagttc gtcagcccta ggaaaaacat cgaagcattt
     2161 ccgatatatt ccccttcatc atacttcaag cgcattttga ttggctttac tcgagggagc
     2221 atctctgctc ctttcgcaag ataagcaaga taaccaaaaa tactctttag ttctgatgga
     2281 acttcataag tcaattctgt caaatagcca cctgcagcga tattgatgaa gtaactgtta
     2341 tcagaaaggc cgatgtccat ttttacggtt tggtgttttt ttatcacttc tgctgctgct
     2401 ttaatattat ctctaggaat ttttaatgct cgagcatagt cgttcgttgt accagctggg
     2461 atgatggcca ttttaggacg gtgttcaagc ggagcgattc cattaaccac ttcgttgatt
     2521 gtgccatcgc caccagctgc cactactaga tcaaaaccta gttctgcgac tctacatgct
     2581 tcattcttgg ctgaatctgg ttctggtgta gttgcatagg cgctggcttc aaatcctgct
     2641 tcttctaatg cctgtaggat atccgccaaa ttttttttca ataattcttt tcccgaggtg
     2701 gggttataaa ttacgcgtgc ttttttcatt ttcagcctct atcgtttcgc taattcatct
     2761 ttaagtagct tattcacgac accaggattt gcttgtcctt tagttgcttt catgatttga
     2821 ccgactagga agccaaccgc acgatctttt ccatttttga aatcatcgac agattgttgg
     2881 ttgttatcca aaatttcatt aatgattggc agtagtttgt tcggatcaga taattgcacc
     2941 caaccatttt tttcaactac ttcttgggct tctccgccat ttgtgatcaa ttcacggaag
     3001 acttttttgg cgatttttga gctgatcgtt ccatcggcga tcaaacgaat cattcctgct
     3061 aagttctcag gtgtcaattt tgtctcagct aattccagtt tctcactgtt caagtaagca
     3121 gaaacttcac ccatcaacca gttagatgct tgcttggcat ctgcaccatt ttccaaaaca
     3181 gcttcaaaaa aatcagacat ttcttttgta agtgtcaata ccattgcgtc atactctgga
     3241 agtccaaact cacggatata gcgttcgcga cgagaagctg gcatctcagg caaactagct
     3301 tttacttttt gaatccattc gtcatcgatc acgaatttcg ggatatcagg ctctgggaag
     3361 taacgataat cactagaccc ttctttgaca cgcatcaaaa ctgttttatt cgttgtttcg
     3421 tcaaaacggc gtgtttcttg ttggatttct cctcctgaaa gaagaacttt tgcttgacgt
     3481 ttttcttcaa aagctaaacc ttttttcacg aaagataaag agttcaagtt tttcaattct
     3541 gctttcgtac cgaactcttc ttgtccataa gggcgaagag aaatattggc atcacagcgc
     3601 atagagcctt cttccatttt cacatcgctg acttctgtaa attggataat tgatcgcaat
     3661 gcttctagat aagcgtatgc ttcttctggt gaacgcatat cagcttcaga aacgatttcg
     3721 atcaaaggcg tgccttgtcg gttcaaatca acgtaagaat aaccgccaat accatgcatg
     3781 ttttttccag catcttcttc taaatggaca cgttcgatcc ggattttttt ctttttacct
     3841 tctacttcga tttcgatcca tccgtcatga ccgattggtt gatcaaattg ggaaatttga
     3901 tatgcttttg gattatctgg gtaaaagtaa tttttccggt caaaatgagt atctttagag
     3961 atttcacagt ttaatgccaa agctgctttc atcccgaatt ccagcgcagc tttattcatt
     4021 actggcagca cgcctggata accccagtcg atcacgtttg tattgctgtt tggttctgca
     4081 ccaaaatgag ctggcgctgg agagaaaatt tttgagttgg tttttaactc gacgtggact
     4141 tctagtccaa tgactgtttc aaaattcatt cgtctttccc tcctaaaata gctggttgtt
     4201 gtttatggaa ttctgttgct tgttcaaacg catatgccgc ttgatacatc gttttttcat
     4261 caaaataatt accgatgatc tgcaatccaa ctggtaatcc ttctgataaa cctgccggta
     4321 cagacatacc tggaagtcca gccaagttga cagggatcgt taagatgtca ctcatgtaca
     4381 ttgtgattgg atcgttaatg ttctcaccga ttccgaatgc aactgttggt gaagatggcc
     4441 cgatgatcaa gtcataatct gcaaagactt tttcaaaatc tcgtttgatc aatgtacgga
     4501 cttgtcccgc ttttttgaag taagcgtcat aataaccagc acttaaggag aatgtaccta
     4561 acatgatacg gcgttttact tcttcaccga atccttctga acgtgagttg acatatacat
     4621 catctaatga tttcacattt tctgagcgat aaccgtagcg gataccatcg aatcgttgca
     4681 agttggaact tgcttctgat gaggcaatga tataataaac agccacaccg tattttgaat
     4741 gaggcaagct gacttcttcc acaacagcac ctaatgaacg gaatgtttct gctgctttca
     4801 atacagcttc ttttacgcca ggggccacac cttcgcctaa gtattcttta ggtaaagcaa
     4861 tcttcattcc tttgatgtcg cctgtcagtc cctctgcaaa atcaggaact gaaacgcctg
     4921 aagaagtacc gtctttttcg tcataaccgc tgatagctgt caatgctaat gcattatctt
     4981 tcaccgtacg ggtcattggt ccgatttggt caagagatga agcaaaggca atcaaaccaa
     5041 aacgtgagac acggccataa gtaggtttca tccctacgat gccgttaaaa gctgctggtt
     5101 ggcggatact tcccccagta tcactaccta aagaaactgg aatttgtcca gctgcaactg
     5161 ctgctgcaga accaccagaa gagccaccag gtacttttgt tgggtcccaa gcattttttg
     5221 ttttcttgaa ataagaagtt tctgtacttc cacccatagc aaattcatcc atgtttagct
     5281 taccaacagg gatcatatct gcttgataga ttttatccat gaccgttgca tcataaattg
     5341 gttcaaaatt gtaaaggatc ttagatgcag cggttgtcaa gatatctttt gttacgatat
     5401 tatccttgat accaattgga ataccagcaa ggacgttgct ttcatcaatc cctttttcat
     5461 ctaaagcttt tgcctgttcc aatgcttttt cttcgttcaa tgtaatgaat gcttcgacct
     5521 caggctctgt ttctttgatt cgttcaaatg ttgcttttgt caaatcttgt acagtgattt
     5581 ctttcgatac aagcatatga tgcagttctt ctagagaacg attgtgtaat tctgtcatta
     5641 tgcgccagcc tccccattat cgatgattgc gggtactttg ataaagccgt cttctgtttc
     5701 cggcacattt ttcaataatt catcgcggtt ccatccagct tgcgcccgat cttgtcgcat
     5761 cacgtttact gtttcaacca cattcgacgt aaatggaaca ccttctgtat ctacttcttc
     5821 cagcatttca accatatcga tgattttacc taattggtcg gtaaaacttg caagttcttc
     5881 atctgcgaac gcaagttttg ctaatttggc aacgtgtttc acttgttctt cactaatcgc
     5941 catactaccc cttctttcta aacgagttaa aaactttgct ctctatttta acacaagagt
     6001 gccgtgtctg aaattgttta ttgaaatttg tctgaaaaaa ctcatttttc attcttctac
     6061 tgagcgactt ttagccaatg catctgccat ttgatcttct gtccaaactt cgattcctaa
     6121 ttcttgtgct ttggtcagct tgctgccagc atcttctcct gctaccacga tatccgtttt
     6181 tttcgatacg ctaccagtca ctttcccgcc aagattttcg atcgtctctt ttgcttcttc
     6241 acgagtaaat cgtgttagtt taccagtaag gactactgtt ttttctttaa aaggagactc
     6301 gacttcttgc aattgggcat ttcgaagccc tttgtattcg aaattgacgc ctgcttgttt
     6361 taattcattc atcaattcat ggacttcttc gttactgaaa taagtgacta cactgtcggc
     6421 aatgatatca ccgatcgtat caagcgcaat aatcgactca tagtcacttt tactcaatgt
     6481 ttctagatca ccgaaatgtt ctgctaaaat ttttgctgct ttcgctccga catgtcggat
     6541 tcctaacccg aaaatcaacc gctcgaccga attatctttg ctgttgtcga ttgctgtcaa
     6601 aatattattt gctgattttt cttttatttt gtccaacgtc aataactctt cttctgtcaa
     6661 tttgtaaaga tcagcaacat ctgctactag ttttttatca tacatctgtt ctagtacgcg
     6721 cggccccaac ccatcgatat tcatcgcatt tcttgaaaca aagtggttca aaccttcttt
     6781 catttgagca gggcatttag gattgatgca ccgtaaggct acttcttcat ccaaatggac
     6841 aagttcactt ccacaaactg gacaatgtgt aggcaattgg tattcttcgc tgtctttagg
     6901 tcgtttatct aacacgactt gcgaaacttc tgggatgatg tctcccgctt tataaatcag
     6961 aactgtatct ttcaagcgga tatccttcaa cttaatataa tcaccgttat gcaggctggc
     7021 acggcttact gtcgttcctg ctactcggac tggtgtcatg atagctgttg gcgttactac
     7081 ccctgttcga ccgactgtcc attcgatgtt ttcgattagc gtttcaactt cttctggcgg
     7141 aaacttgtaa gctgctgccc atctcggtgc tttgacagta aaaccaagtt gatcttgtag
     7201 cgagaattca ttcactttga tgacgattcc atcgatttca tagggcaaat ccacacgttt
     7261 gtcatgatat tcttcaatgt atgaccacac ttcatcaatc gaatgacata gacgtttttc
     7321 ccgattcgtg tggaatccaa ttttttctag ctcttctagc gcatcatact gggtttttgc
     7381 ttgcatagga ccgaaatcag ctactgtgta taaaaaagtg tccagatttc ttttcgctgt
     7441 gattttagaa tctaactgac gcaaagaacc agctgcggcg ttccgaggat tcgcaaagat
     7501 atcttttccc tctgcttctc tgtcttggtt caattggaca aatgaccgtt ttggcatgaa
     7561 acattcgcct cttacttcga tgttcattgg ttcttttaat ttgattggga ccgaccggac
     7621 agtttttagg ttttcagtga tgttttctcc tacagttcca tccccgcgag tcgcacctct
     7681 cacgaaattt ccatcttcat aacgcaaaga aacggaaagt ccatctattt ttagttcaca
     7741 gcaatagtca actacacgtc ccactgcttt ttgtacacgt tgatcaaaag ctatcagctc
     7801 ttctttgctg aaaacgtcgt tcaaactgta aagcggaata tcatgagtga ctttttcaaa
     7861 accttctaat acttttccgc ctactcgttg agtgggagaa tcagacgtga tcaaatcagg
     7921 atattgttcc tcaattgcta ctaattctgc gtattcttta tcataaacat agtcttccac
     7981 tgttggttta tcttctacgt agtattcgcg agaccattgg ttcagtcttg tacgaagttc
     8041 ttctgctcgt ttagcagctt cgtcaatcgt catttcatgt tccatcattt accctccact
     8101 actaagcttt ttcaattggc gcaaaggcag ccaaaagacg ttttactcct tgacttggga
     8161 aagccacatc tagttctaga tccttcgacg tcccgcttac tcggacgact gttcctagac
     8221 cccatttttt gtgtttgact ttatctccag gtttccagct gttattttcc cctccagtag
     8281 cacttttaga gggaacaacc gctgtctctg gctgtttata gctatatgct gtttttttag
     8341 cgaatacagg tgttttttta ggcgtaggac gcatgccttc gatttccagt aactcctgat
     8401 cgatttcttc tacaaaacga gaaggtcggt tatattgcgt ccgtccatat aatgttctgg
     8461 agaaagcatt tgttaaatac aacgcttctt ctgctcgcgt gatccccaca tatgcgagac
     8521 ggcgttcttc ttccagttcg ctttcttcca tcaatgctcg agataaagga aaaaccccct
     8581 cttctagacc aatcaggaat acaactggga attctaatcc tttggctgca tgcaaagtca
     8641 tcaatgtcac ttgggaagca tcttcttcta aattgtcaat atcggaaaca agtgccagat
     8701 catttaagaa gaccgttagt ttttcttctg gtgcatcagc gtcttcttca ttttgctgtt
     8761 cgaattgttt gtcgaattct tgtgtgaccg ttaaaaattc ctccaagttt tcgatgcgtg
     8821 cttgtgcttc taatgtattt tggattttta agtcttctag atatccgcta cgatccaaaa
     8881 cctctttcgt caattctgtc actgtcaagt atgggatcat ctgagtgact tcttggatca
     8941 tctctccaaa tgcacctaat tgctgtcctg cttttccacc gatatttgcc agatccacat
     9001 tttgcgctgc ttcaagcagt ggccattcat gaagagaagc aaaactgcgt agtttttcga
     9061 tagatcctgg tccgatgcct cgtttgggcg aattaacgat acgctcaaaa ctgattgaat
     9121 cttgaggatt tgccagcaca ttcaaatacg ctaaaatatc tttgatttct ttacgatcgt
     9181 agaacttgtg ccctccaacc attttataag gaatatttgc tttcaacaga gtttcttcca
     9241 ttacacgaga ttgtgcgttc gtccggtaca agatggcaaa gtcgccgtaa ttccgatgat
     9301 tgcttcgaat ctcttcttgc atccgatcta cgataaaacg ggtttcgtct cgttcattat
     9361 ctgcacggta gtaagtgatc ttgtttcctt ctttgttttc tgtccacaag ttttttggtt
     9421 ttcgattgct attgttttca atgacttggt ttgctgcgct aaggatgttt ttcgtggagc
     9481 gatagttttg ttctagcaaa attactgcag catctggata atctttttca aaatccaaga
     9541 tgttctgcat atctgcaccg cgccagccgt aaatactttg atctgcatct cccacgacgc
     9601 acaggttcct aaatctacct gccaataaat tgactagcgt atactgtgcg tgatttgtat
     9661 cttggtactc atctacatga atataatgga atttgttttg ataatatgtg agtgaatcag
     9721 gatgttcttc aaataatcga atcgtattca tgatcaggtc gtcaaagtcc atacattgat
     9781 tatattgaag ctctttttgg taagcagcat aacattttgc cgcaatctct tcgtaataac
     9841 tgccttgcat ttttgcaaaa tcctgagggg tctgcaggct gttttttgct tgagagattg
     9901 ttcctaatat acttcgagga tcatattttt tcggatcaat gttcagttct tttagtatcc
     9961 gtttcatcaa ggtcagctgt tcagaagaat cgatgattgt aaagttccgg ttatacccga
    10021 taaaatcaac atctcttctt aaaatacgca cacacatcga gtgaaaagtc gatacccaga
    10081 catcttcgcc tccagatgcg agaatcgcat tgacacgttc tttcatttct tttgcagcct
    10141 tattggtaaa agtaatcgct aggatgttcc aaggattgac ttctttttcc tcaatcaaat
    10201 aggcaatgcg gtgtgtcagc actctcgtct ttccacttcc tgcacctgcc attagcagta
    10261 atggtccgtc agtgtgaaga acagcttctt tctgacgggg gttcatcccg tttaataatt
    10321 cagctttgga tgacattaac aacatccttt cttttatcaa tcttgttaat tatagcattt
    10381 tcttggcttt cattaaacta gctagttcaa aatcatttgt ttctttttat ggatttttcc
    10441 ttgtcaattc gttgatttcg cgctaaatta aaagaaagcg aggcgtttga atggaaaaaa
    10501 aaggaaaaat caagaaatta gataagactc agatatattt tattctaaaa ggaatatttg
    10561 ttggactgct gacaggaatc gtcgttagcc tgtttcgatt atctatcgaa aagctaagcg
    10621 atttagttcg aagtatctat gaaatgagtc gggaacagcc gatttactta attggcctag
    10681 ctatttgctg catccttgca gcatttttcg tgggttatct ggtcaaaaat gaaccggata
    10741 tcaagggaag cgggattcca caagtagagg gacagcttcg cggggaatta tcaatgaact
    10801 ggttctctgt tttatggaaa aagttcattg gcggtgtact ttcagttggt gcgggccttt
    10861 ttctaggtag agaaggacct tctatacagc ttggcgcatc cattggacaa ggagctggac
    10921 aattgtttcg gagtccatct tcagaagaaa agattttaat ttctagcggt gcaagtagcg
    10981 gacttgcagc agcattcaat gctcctatcg caggattact ctttgtttta gaagaaatcc
    11041 atcactcctt ttctccactt gtttggctga catcatttgc ttcagcaatc actgctaact
    11101 tcgtctctct ttactttttc ggcttgagac ctgttttata tctaggtgac cttccttctt
    11161 tgccgttgaa atattatggt tccttagtga tcttaggagt acttctaggc atcttaggtt
    11221 ttatttatca gaaggtcttg ctggctttgc caaaatttta caaccgattg cctttaccag
    11281 cttattttca cgggttcgtt cctttcttgc tgattttgcc aattggttat ttatggccta
    11341 gtactctagg cggaggcaat caaatcgttt tagcttttgg acatgcttcc ttgccaatca
    11401 ttatgattat cggtttgttt gttcttcgat tcgttttttc catgatttct tacggtggtg
    11461 gtcttccagg ggggattttc cttccgatat tgacattggg ggctttaatc ggtagctttt
    11521 atggaaacat tatggttgat ttcgggatgg atccaatcta catcaaggat tttgtcgtta
    11581 ttgccatggc tggttatttc acagcgattg gaaaagcacc gctgacagca attattttag
    11641 tgacagaaat ggttggctct cttaatcatc tgatgccttt aggattggct gctcttgttg
    11701 cttatatcgt caatgacctt ctcggcggta atccaattta cgaatcatta ttggaacgtc
    11761 tacttggaaa tactcagacc gcctcactaa aaggtgcaag gacaactttt gattttccag
    11821 taacggcaga gagttcttta gacggattaa tggtacgaga cttcaattgg cctaaaaata
    11881 tgctgctaat ctctatacgc agaggaaatc aggaaatctt gactcacggt gatacgatca
    11941 tgaatgtagg agatattttg gttatcttga ctgatgaagc aaacttgcca agaatcaagc
    12001 aggaaatcga ggctaaatct tctatcacaa atttgaagca atcattttaa cgaacatgga
    12061 aaaactattt tacaacaact attcatctac actacttgat tctatatgat tctataaaaa
    12121 aagaagagac tgggaaaaac cagcctcttc ttttttattt ctatgcttct gctgctgcag
    12181 gagcttttct caataaacca taaatcacac cagatacgac tgctccgata gcaataaaca
    12241 ccaaatacat gaccgggtga ctcagtaaga atacaacgaa aatcccgcca tgaggagcca
    12301 gtaatttgat cccgaaagct ccgactaatc cgccagttaa agcagaacca ataataaaac
    12361 ttggaatggc acgaatcggg tcagctgctg caaatggaat cgatccttcc gtgacaaacg
    12421 atagtcccat cacgatgttc gtcaaaccag catcttgatc tgttttgctg aatttattct
    12481 taaacaaacg tgtagcaacg aaaattgcca atggaggtac cattcctcca gccataacag
    12541 aagccatcac gacacttccg ccagttgcaa cagtcgtagc taaagttgct gtaccaaaca
    12601 cataagcggc tttgttgatt ggaccgccta aatctgccgc catcattcca gctaataatg
    12661 caccaagtaa agcagcattc gaaccactca tacttgtcaa gaaaccgttc aatgcatcat
    12721 tgattgcttt catagggaca ttgaccagca acatcaagaa accagtaatc agtaagccaa
    12781 acactggata aaagaggatc gttttaattc catccaatga ttttggtaag ttcttgaata
    12841 atttacgtaa aaatacgatg acataaccag ctaagaatcc accaatcagt gcacctaaga
    12901 atcctgcacc gcctgtatta gctaatgcac cagcagcaaa tccaacgatc aaaccagggc
    12961 ggtcaccgat acttgaagca ataaatcctg ctaataccgg cagcatgaaa ccaaatgcag
    13021 cttgtccgat ttggttgaac cagctagcag cttgattgta attccctaga tttgataatt
    13081 gatcatgtgg cacgccaata aattggtcga tcatgaaaga aagcgcaata gcgattcctc
    13141 caccaataac gaaaggtaac atgtgtgata cgccgttcat caaatctttg taaattcttt
    13201 gtccgatagt accatccgca tttccttctt ctgaactgct ttcttttcca tcaccatgga
    13261 atactggtgc agtaccacta agggctagat tgatcagctc ttctggttta cggataccat
    13321 cactgacagg acgattgatc agttcttttc cgtcaaagcg attcatctct acttttttgt
    13381 ctgctgcaac gattacacct tctgcacggg cgatgtcttc agcagtcaat cggtttttga
    13441 ttccttctga accgttcgtt tcgactttga tctccacacc catttctttc gcttttttct
    13501 tcagagcatc ttctgccatg taagtgtgag cgatccctgt tggacaagct gtaacggcaa
    13561 caacgaattt tctttctgga tgagcagaag cttctgcagc ttgtgtttct tgttctgctt
    13621 tttcttctgc ttctttttgc tcttcagctg tttggaacaa gtcttggact tcttctggtg
    13681 tatttgcttc ttttaatttt cctacgaaat ctgcatcaat cagcaatcga gatagtgctg
    13741 ctaatgcttg caaatgtgtg tcgtttgcgc cttctggagc tgcgatcatg aaaaacagat
    13801 aagttggctg tccgtctaag gcttcataat ctactccttt ttggcttttt gcgaataaaa
    13861 ctgttgcttc tttaactgca ctgtttttcg cgtgaggcat ggcgattcca tcaccaagac
    13921 ctgtagaagt ttgtgcttcg cgggctagaa ttccttcttt atatgtttcg atatcggaaa
    13981 tccggccggc atcaaacatt ttttggacca tttcatcgat tgcgcctttt ttatcagtcg
    14041 cttgcaaatc catgatcatc gcttctttga ccattaaatc cttgatattc atgattatcc
    14101 tccttgaaac taatcaattt ttgtgatttc aacttctggc agcaactcat caatcaattc
    14161 gcgagctgcc aagtcatcag aaaaagctgt tgcgcttccg caagcaactc cccatttaaa
    14221 ggcttcgatt ggatctttcg tacggctgta agccccaata aagccggcaa tcattgaatc
    14281 ccctgcacct actgaatttt tcaatgggcg aactaataca ttcgttttat aagttccttg
    14341 ttccgtgaag agcaaagcac cgtctccagc cattgagatc agcacattct gtgccccttc
    14401 agctagcaat tttttaccat acggaatgat ttcttctaca gattggaagg ttgtattgta
    14461 aagctcagct aattcgtgat tgtttggttt gatcaacaat ggtttcttaa caagtgcatt
    14521 ttttaggtca tcacctgttg tatcaatcac gaaatctgca cctttttctc gaatgatatc
    14581 aatcagttct tgataaaatc cttttcgcag gctagccggc gcgcttcctg acaatacgac
    14641 gatatctcct tgtcctactg ttcctaatgc ttgcttcaac tcatcgattt cttcatctga
    14701 aatagatggg cccaaaccgt taatttcagt ttcagtatct gattttagtt tgatattgat
    14761 tcttgtatct tcttttacgg ttgtgaacaa agactggatt tgttcttttt caagccactt
    14821 cgaaataaat tcgccagtga accctcctaa aaaccctagt gctgtagatt gagaatcgat
    14881 ccgtttcaaa atacgggaaa cattgatccc ttttcctcca ggtaacttga agtcttcctt
    14941 cattcggttc aaatcgccta gttttaaccc atctacgcgt acgatataat caattgatgg
    15001 attaagtgtt actgtgtaaa tcattgtatt gcctccttaa ttgttgtctt ttcacggaat
    15061 tcattaacga attctaatgg acaacgctcg gttatgatcg tggctgcttc caaaggtgca
    15121 acagaggtga aggacaactg gttgaatttg gtatgatcaa tcaatacaaa tgtctcttcg
    15181 gaatttttca tggctaaacg tttaacagct gcctcttctg ggtccggagt cgtgaatcct
    15241 tgttcaagat gggcaccgtt cattcccata aatgctttat taaaatgaaa attttttagt
    15301 tgttctatcg cattagatcc taaaacagca ttagttgcca gctttatcgt tccacctaaa
    15361 ataatggtag caagctccaa atcaactaaa tttgccgcat gttgaacgga atttgtcact
    15421 actgtgatct gttttccttg cagaaaagga atcatttcta acgtagtaga gccagcgtct
    15481 aaataaatga catcttcgtc attaatggtt tcagctgccg atttggcgat ttgctgtttt
    15541 tcgtgaacgt ttttgagtga tttttcactc atattctgct caaaattcaa taattgctct
    15601 ttcttagctc cgccatgaac tctttctaga aacccactat tctccagctc ttgtaaatca
    15661 cgtcttatcg ttgattcaga agcattaaaa aggtttacaa gatcttgtga tttcacgatt
    15721 ttctgctgtt caagcaagtc taggattttt tgtctacgtt cctctgtaag cattttcacg
    15781 atcacctcaa tacaaataat agcatatttt ttttctactc gcaatataaa tcagtcaaaa
    15841 acgttcataa aaattataaa tcagtcaaaa aaaaataaaa aaccagtcaa aaagactggt
    15901 tttttatttt tttgtctatc atcaagccgt tttatcgttt tttattttcg cttcttgttt
    15961 ttttcatata aacagaagca ggttttcttt ccttatgaag aagataataa taaagtccca
    16021 tcccgccaaa catgaccaaa aaaccgatga ctgatcgaat aggaaaatta ggaacaaaaa
    16081 agagacagac ggataataat gatgccggaa ccattattcg ataatagagt tgtttatcca
    16141 ttttcttcac ctcatatttt ttgtaaagta atcaattgtt ctaattctcg gtaatctaaa
    16201 aattgcacac gcagatgctg ctcacctttc ttgacatcga attggatact tcgccgcttt
    16261 ttctttattc gtttgaaggt aacatcagag agtctatgtt tgatttcctt taacggtaat
    16321 tctgacaggg attctgaagg aacatagatt cttaaggata aaagatactc ttgatatttt
    16381 tcatctgtta cctctacttc tagatattcc ctaatataat aacaataagc ttcgattcca
    16441 ttatccaaag caacagtcgg atcgataact ttatagcaca tcatgcgcga gcgattctcg
    16501 tcaacccaag gaaaatacgc ctgagcattt agtgttccgc gaacacgcct ttctttataa
    16561 tctccttgtt gaatatcata actttttgtt acaaaaaatg aagcattctt tttaggaaca
    16621 ggttgcattt gtgcattctg atactggaca gattggatcg tatggtcagt gtaaatgtat
    16681 tcaacgaatg gcggtttcaa taaaccgaca ccattgtccc aagcaagatg atcaaaccca
    16741 agctggtccc taaaatagga ttgaaacatt tgattgtttg gcttttgcca gttaaagggg
    16801 tctcgataaa gctggataca tatgacttcg ttttctaatt ccttcacttt ttctacttgt
    16861 tggatgtcga gaaaaatcgg tttagggatg atttgatgat aatagcgact ataatacatt
    16921 tcccaacacg aagtgaaaca taaaccttgg taaaaaagat cgtatcctgg aaattggttg
    16981 caatcgacta ctacttcccc gttttgttgt ttcattttag gtaaatgttc gatttcatcc
    17041 tttttctcaa acaatagccg ttgagagatc tgttttgtat tgtgatagat aaactcgcta
    17101 taagctcgca tataggcgaa caccccatga gcaatcattt ttttctgaat gaagtctcga
    17161 atcaaaaatt gcttttcttt gaaaacagag atagacaata cattttttat caataattga
    17221 ttatcttcca agcgaaaact acattcgttc tcgtcatttc ctacaactaa ccaactttcg
    17281 tctcttaccg atgctagcat tattttttct tgaagctttc gaagatcata cggatccgct
    17341 tgttgtgtga aagagcggat aaatgttggc tggatcaaca gacgtgtcaa aatagcccaa
    17401 tcgcttattt cctgtttttt ttcttcttca tttaagtctg tgagctggat agtcatcaat
    17461 aatttatctt cgccaatcat tttctcacct ctttaaaatc tttttataat ttaattataa
    17521 ccaacgataa agaaaaacta aaactttatg tcttagaaac caatttggac gattacatga
    17581 tagactaagt aaaaagaaac aaagaggtgt ttacaatggg gttgaaattt gaacgtacag
    17641 ataatttaga taaacttttc gaatcatttg ctgtcgatcc ggaaaaaaca gttgcaccaa
    17701 aagaagagat cgatcgattt ctaaaaccac agccacaaaa tgaaaagaaa aaagacaaga
    17761 aacaaaagta agttaagctc aaaaaaagac ttaccagcca aacttttatg aaagagtttg
    17821 actggtaagt cttttttatt ctttttatga ttcaattgct tgttcgattg ctgcccacgc
    17881 ttcttctttt ccctgttttg taacggaaga aaagagaata aacgtgtcat tgcgatcaaa
    17941 atccaacgct tttttgattt cgctctcatg cttgttccat ttaccacgag ggatcttatc
    18001 tgccttagtg gcaacaacaa ttacagggat atcataatac ttcaaaaatt gatacatctg
    18061 gatatcttct tgagaaggct tatgacgcaa atctactaaa gaaacgaccg cacgtagctg
    18121 gtctctagtc gttaaatatg tctcgatcat ctttccccat tttgctcgct cagttttgga
    18181 tacttttgca tacccatatc ccggaacatc gacaaaatgt aatgcgttct cgatcaaata
    18241 aaaattcaat gtctgggtct ttcctggctt accggaagta cgggctaaat tctttcgatc
    18301 aatcaatgtg ttgataaaag aagatttccc tacatttgat cgtcctgcca gagctatttc
    18361 tggcaattgt gtatctggat attgttttgg tgccactgca cttatgataa tttcagcttg
    18421 atggactttc atggtctctc tccttaacaa ggtgatgaat aaagcaagcg gctgtcgcaa
    18481 aagccaaaat gacttttacg gcagcctctt ttcatcaacc cgcttttttc tctgaatctt
    18541 tatagattac tgttggctca ccagacaatt cagctgcttc ttttgtgata atcacttttt
    18601 cgatgttttc atttgaaggg atatcaaaca tcacatccat catgatttct tcaatgatgg
    18661 aacgaagtcc tcgagcaccg gtattgcgtt cgattgcttt tttcgcaatg gctctcaacg
    18721 cttcaggttc gaattcaagt tcggtattat ctagagaaag aagtttttga tattgtttga
    18781 ctagcgcatt tttcggctca gtcaagatcc gtaccagatc atctgttgtc aatttctcta
    18841 aagctgccat aacaggtaat cgtccgataa actcagggat caatccgaat tttagtaaat
    18901 cttcaggaat gatatgctgc atgacacttt cgtcttcaga aagtttttgg ttttgtgtac
    18961 caaatccaat cgtcttttcg cccatacgat tcttcacaat cgtttcgatg ccatcaaatg
    19021 caccacctac gatgaacaat atgttcgtcg tatcaatctg aataaattct tgatgtggat
    19081 gtttacgtcc tccctgaggt ggcacgcttg caacagttcc ttctagaatt ttcagcaagg
    19141 cttgttggac accttcgccg gaaacgtcac gagtaataga tacattttcg cttttacgcg
    19201 caattttatc gatctcatca atatagatga tccctttttc tgcacgttcc acattgtaat
    19261 cagcagattg aagcaattta agcaaaatgt tttctacatc ttcccccaca taaccagctt
    19321 ctgtcaaact tgtcgcatct gcgattgcaa aaggtacatt caatgttttt gctaatgttt
    19381 gtgctaaaaa tgttttacca gaccctgtag gtccgatcaa gcagatattg cttttttgca
    19441 gttcaacatc atctgtgttt tcttgtgctt gctgattgac acgtttatag tgattgtata
    19501 cggcaacagc taacgagcgt tttgcgcgat cttgtccaat cacgtagtta ttcaatactt
    19561 caagaatttc tagtggttta gggacttcag tgaattcgcg tacagcttct tcataaaatt
    19621 cttcatcaat gatttcttta cataggtcga tacattcatt acagatgtag acccctggac
    19681 cagctacgat ctttttcact tcttcttggg ttttcccgca aaaagaacag cgtacggtct
    19741 cattgctact tggattgtca tacatggtct tcacccctta acttgcaaaa agtatgcaag
    19801 aaactatcaa agactttaca gtcttttact atcataacat agtttagtaa aaagaaaaag
    19861 tgtttaacaa aggatcaact gacctatacc tttgcatttt ttactcttaa caaaaaataa
    19921 ggaactgtga caaaatcgtg tcacagtccc ttatttcgaa taaacaattt tctagaagta
    19981 gcttcttcag aaatgattta ttacttgatt tctattcttt cgcttctgtc gctgtacctg
    20041 tgatcaattc gattgctttt ttcattgtca catcatgttc cagcatatct tctgtcaaca
    20101 cgcgtttgat ttgttcgatt ggcatgttgt atgtttctga taattcttgg atttctgcat
    20161 tgatttcttc ttctgttgct tgaagatttt cagcagctgc aattgcttcg atcacaagat
    20221 ttgttcttgt gcgcatttct gcttcacctt cgaattgttt atgcaagtct tcttctgtag
    20281 aaccagttaa ttgatagtac atttcaggag agataccttg acgttgcatg ttgttcaaga
    20341 attcgtccat tgaacgatgt acttcatcat gaaccatcac gtgtggcaat tcaacgattt
    20401 ctgcgttttc aacagccata cggatcgctg cttcatcttt tgcatcgtcc gctgcttttt
    20461 cttttgtttc tactaattct ttgcgatatt tttctttcaa ttcgtctaat gttgatactt
    20521 cgtcatcaac atcttttgcg aattcgtcat ctaattcagg cacttctttt gcttttactt
    20581 catggattgt cactttgaag actgcttctt ttccagcaag atcttctgct tgataatctt
    20641 ctgggaaagt tacatttaca tctagacttt cacctgattt atgaccaact aattgatctt
    20701 caaaacctgg aatgaatgag cctgaaccta attcaagtga gtaattttcg ccttttccgc
    20761 catcaaacgc ttcgccatct acaaagcctt cgaagtcgat tactactgta tcgccatttt
    20821 cagctgcagc atcttctttg ataactaatt cagcttgtgc ttcttgttca cgtttgatac
    20881 gtgcatccac gtcagcatct gttacttcac ggtcttgttt ttcaacaact agatctttat
    20941 attgtcctaa ttttacttct ggtttcactg ttacttcagc agtgattacc cagtcttgac
    21001 ctttttccat gctttcaaca tcgatttttg gttgagaaac aggatcgatg ccagcttctt
    21061 tgacagcagc ttcataagct tctggtaata cagcattcaa tgcatcttca tataaagctt
    21121 cttcaccgta catacggttg aatacttgac gagaaacttt ccctttacgg aatccaggta
    21181 cgttcaagct ttttttcact ttattaaacg cagttgttaa tcctttttgg atttcgtctt
    21241 gcgcaatcgt aaattttaaa acaccatcat tcgtgccttt tttttcaaat gttgcagtca
    21301 tttaattccc tccgagttta gaaattcatt ttatacatca aaaacgtttc atgcatacct
    21361 ttaaatagta cactaaccct ttcaaattgt aaacatattg aatggataga atccttgttt
    21421 ttcataacat ttttatcttt ttcactgata aaatctaatg gaagaagatc atttgctgca
    21481 aaattttttc tctttttttt aaaaaatctt gtttttcatc ttctgtacct tcatacatcg
    21541 tttttcctgt acacgcctct acagtcagtt gaaaccagcg cttcgggtct tcgatgtatg
    21601 tatcatagac aggataaaca attgcagatt gcaacgtgaa ttcttcattt aacacggaac
    21661 taagcagcgc atcttcatta ccgtaacgat ctgaaaatac acataattgc tggtaacttg
    21721 cctgctgctg cggctttggc agatcttttg gtatgacttt gactaacttt tcttcaatcg
    21781 tcaaatagaa aacaggatgg cattcgttca attgcctaag tgtctccagt aattttgccc
    21841 ttgctaaaat atggacctct ggcgatacaa taagtttact cgctgtttgg ataaactcat
    21901 gataaggaag ctgttcgatc tcatcaatag acgcaagctg acgtgcaggt tccaacgaag
    21961 gaagttcctc cgatttattg tggagtgcct tgatcttctg cctctccatt tgtccggata
    22021 attcttctgc aaattggatt ttttcaatga cccgctgctc gaaagcttca taaaaatctg
    22081 tacttgctat caattttcta gcatataaaa aatcttgtgt actgattaac aagtcaaaat
    22141 aaaattcagc aaactcctca ttttgaagat actgtttttc atgcaagagt gcttgcttca
    22201 atgcttcttt tttctcgtcc aactcgtaaa gacaaaaaac aagcaggcta ttagcctcaa
    22261 agctttcttt caactcgtaa gctcgttgaa ataattcttt tgcctgctga tattgctggt
    22321 ttgctagtgc ttgttgtgct actcgcatta aattctcata tttttctgga aaatcaatcg
    22381 gcttcacgca gtgtcctcct cttgctcatg ttcagctcat gttcaatagt agcaaaacaa
    22441 aaaaagcatg acaattaaaa ataactgaag caccctctaa aagctagatt ttagatctga
    22501 cttttagaag gtgctttcaa ctgttactgc tttttattgc tcatcagctg ttgacttcct
    22561 ggttgaatgc tttgatcaga ttgatcgtaa caacacttgt attagtgaaa aaatcgccta
    22621 gatgttgctt tttctgatta aagattgctg gaagataccc taacatcagc aaaggaaatt
    22681 ttagaatgaa ccggcaagca ccttctctaa ctaaaacggt tgaccagcta agttcttctt
    22741 catcaaagct gatgactcga ataccaaaga tcattttccc aatcgtttga ccatgattga
    22801 atttcgtcaa taaaataaaa tacgctagat aaataagtaa ggctgtgaat ccgtagatac
    22861 tcagataaga atctgaaaaa ttaagccaac ctagattttt ggcaatacca agtgttaaac
    22921 gcgtaatagc tccgatacac aaaagatcga ccaagaaagc aaacattcgg ataaaaaaac
    22981 ctgcatagaa atacttagga aaatcatttg cttttggcgg ttcatttctt gtgtccgtat
    23041 actttttcca tttacgttgt ttctttttga tttcttcggg cgtcaaaggc tctctttcaa
    23101 aagagctcag taccttttgg gaaaagttgg agtcaggtcc tacagcaggc tgctgttgct
    23161 tatctttttc ttgttcctta ttttcatttg aaagctctga catgcttact cacctccgta
    23221 ataatacatt gcttttggtg attccgctgt ccctagattc tcaagaacgg ataagatctg
    23281 actagtctca gaaggcttca atccctggaa ttctgctagt ttacttccta accatgtact
    23341 agcaaaccca gatggcgtgg aagaatattc tactagttcc gcatcttcaa gctgttgttc
    23401 ctttcgcata gcttttaaag catcttcagg aaatcccaat tcatcgacta aacctacttc
    23461 ttttgcttgg acaccatcat aaatccttcc atcagcaatt tttttgactt cttcttcaga
    23521 tttattccgt ccctcgctga cgattgctac aaaacgacta tatgcgctgt cgatatatgc
    23581 ttgaagcacc gcttcttctt cttttgtctc tggtcgcgtt cctgaaccca tatctttcaa
    23641 cgctccgctt ttaactgttg tatcttccac acccagtttt tctagaagtc ctgaataatt
    23701 caatcctgac atgatcacac caattgagcc ggtcactgtt tcttctgttg caaagatttt
    23761 atctgcttga gcagaaatat agtagccacc gctagctgcc atgtttttca tgctgacata
    23821 cattgggata tcatgttctt tacgaatcgt atccaatttc ttagcgattt ccgcactttc
    23881 gtagacaccg ccaccaggag aatttacttc taaaaagata cctttgactg ttggatcttc
    23941 ttcaatcgcc ttcagttgtt ccataaaatt tttatgattg taaccttcag aagcaaataa
    24001 acctgaagac cctcccgcag caatcgttcc atctactgat aattttacga ttttttgcgt
    24061 actgtctccc tcttccaaca catttgaagc tagttcttca tccccatata accaactgtt
    24121 caatccctca atttgatcgt tttcctgagg cttagtcaaa ctagctgaaa ctaacgaaac
    24181 cacaaataat cctgcagcaa tcagaactgc tgcccaacgt ctcttattca ttctttctcc
    24241 tttctaatac aagtttttta tgacgatcac agtttctgac tgctcagaag tgtcgaaccg
    24301 ctctgctttt tcttcccgcg catacccgga aaacgactct tttgtcaatt catcttctac
    24361 cgtaaactca cgagcttcag caacttccaa ggcatcaggt gcgatttctt ggatgctatc
    24421 ccagccagta tctaaaaata ttttcgtatc atctgataca ccagctgatg cttcgaattt
    24481 ggacaattgt ttttttaaca ttcccagtgt catgatctca atttttgaat ccatttttac
    24541 tcctcctcta tccgattact ttctattgta ccgaactcct gaaaaagatg atagataaaa
    24601 acccattatt ttttgacata aaaagagcat ttgacaaagc atttgatata taccaattta
    24661 ttttttattc tttttttgtt gacaagaaca ttcgcaaaag gttatgattt taaatgtttc
    24721 cagataaaaa acaaaagagg aggatagtta taccttttag gatagcgcca ggtctgtgta
    24781 aacagatgac gaggagaggg tttatcgaaa gattcggcgg atggccctag ggactgcact
    24841 ctacagaaaa tccacaaaaa atatctgcaa agataaaaca aaaggatttt cctgcagctg
    24901 gaagcattca tacgaattca ttatagaaag taggatgttt tttatgtgcg gaattgttgg
    24961 aatgattgga ttaaaaaatg taacaccagg attgattgac ggtctagaaa aattagaata
    25021 ccgtggttat gattcagctg gtatctttgt ctcagatggc acaactgatt atctggtcaa
    25081 agcacaaggc agaattcaaa atttgaaaaa caaaataaat attgatacta caggaaatat
    25141 aggtattggt catacacgct gggcaactca cgggcaacct tctgaagaaa acgcccatcc
    25201 acatacttcc caaagtggac gcttcgtgct cgttcacaat ggcgtaatcg aaaactttga
    25261 agaacttaaa attgcttatt tagcaaatga ccactttatt ggtgagaccg atactgagat
    25321 tatcgctcat ctaattgaaa ctttcgcgaa ggatactaca acgcaagagg cgtttttaaa
    25381 agctttgcgg gtcatcaaag gttcttacgc tttcgctttg attgatcgga cagcacctga
    25441 tgttatttac gtcgctaaaa ataaaagtcc actattaatc ggactcggcg atggattcaa
    25501 tgtgattgcc agcgatgcaa tggctatgct tgctcatacg aaggaattcg ttgagattga
    25561 agatgaagag atggttaccg tcacatcaga aaaagttatt attcaaaatt ttgcaggtga
    25621 catcgtagaa cgttcttcat tcgaagcaca agtagattct tcagatatcg agaaaggtac
    25681 ctatcctttt tatatgctga aagaaatcga cgaacagcct attatcatgc gtcgtatcgc
    25741 tcaaaaatac gtaacagaag acaatcgtgt ctctcttgat caaaagctgg tcgatacatt
    25801 gtctgatagc gatcgaatct atatcgttgc ttgcggaact agttaccatg cggggttagc
    25861 aggtaaacag actctggaaa aattgacaca gatccctgtt gaggttcatt tagccagtga
    25921 atttggctat aacacacctc ttctttcaaa aaaaccattc tttattttct tgagtcaaag
    25981 tggcgaaaca gcagatagcc gccaagttct ggtaaaaatc aaccgtctcg gctacccttc
    26041 acttacgatt acaaatgttg ctggttctac tctttcgcgg gaagcatcct ttacactgct
    26101 attgcatgct ggacccgaaa tcgcagtagc atcaacgaaa gcttatactg cacaaatagc
    26161 tgtactaact ttattagcca aagctatcgg tgataaaaaa gaatttgaaa cttctcttgt
    26221 attcgatatc actcatgaat tgagtttagt tgctaatgcg atggaatcgg tcatcgccca
    26281 aaaagattat ttagaagagt tggcagaagt atatctcagc gatacaagaa atgcctttta
    26341 cattggacgt ggcgctgact acaacgtttc tcttgaagct gctttgaaat tgaaagaaat
    26401 cagttatatc caggcagaag gttttgccgc tggcgaattg aaacatggaa cgattgcttt
    26461 gatcgaagaa ggaacaccag tgattggaat catcagtgaa gaagtgactg gtgcgcatac
    26521 tcgaggaaac ctgaaagaag tcgaaagccg tggcgctaaa acactagtta ttgtctcaga
    26581 gggattagaa aaggaaagtg accagctggt gctaccaact gtccaccctt atctaactac
    26641 tctaaccaca gtcgtaccga ctcaattact tgcatattac gcaacgctat tacggggatt
    26701 cgacgttgac aaaccacgta atttagcgaa atcagtgaca gtagaataat aaaagaacaa
    26761 ggaccagtgt cagacatctg acactggtcc ttgttctttt attttttatg aaaatatctc
    26821 ttaatccagt ccgatttctt ctttgactac tgccgcgatt ttatcgacat agtaattaac
    26881 tttctcatca gtaggcgctt ctgccatcac tcgaagtaat ggttctgtac cggaaggacg
    26941 aactaggatt cttccttctg atcccatttc agcttctgcc tcttcaatca cttttttgat
    27001 tgccggaaca tccatcgcac cgtttttatc acttactcgg atattcacta atttttgcgg
    27061 atagattgtt acctctgctg caagctctga taatttctta cctgtctgtt tcatgatatt
    27121 cagtaactga attcctgaaa gcatcccatc tccagttgtg ttaaaatcta agaaaatcat
    27181 gtgcccagac tgctcgccgc caaagttata atcgtttttg cgcatttctt ctacaacgta
    27241 acgatcacca acttgtgtaa cgacatcttt caaaccgatt ccttccaccg ctttgtggaa
    27301 tcctaagtta ctcatgacag tcgtaacgat cgtatctttt ttcaatcgat ttttttctgc
    27361 caagtattta gcacagataa acatgatttt atcaccgtcg acaatgtttc caagttcatc
    27421 caccgcaata atacgatcgc catcgccatc gaaagctagt ccagcatctg ctcctttttc
    27481 aacgaccatc tcagctaaac gttctggatg ggtagagcct acgccatcat tgatatttaa
    27541 cccgtctgga tttgtgccca tggtataaaa atctgtttca agatcggcaa acaaacgatt
    27601 aacacttgtt gaagttgctc cgtttgctgc atcgacacaa atggtcaaac cggaaaggtc
    27661 accgttgatc gtttgtacaa ggaattgaga atatttcaat aagccttctg gaaattcttc
    27721 tacagttccc aatccttcag ctgatggacg aggcaattca tccacttcag catctaataa
    27781 tgcttcaatt tctagctctt ggtcatctac tagtttaaaa ccatctgcac cgaaaaattt
    27841 gattccatta tcttgtgctg gattatgaga agcagaaatc atgacccctg cgcttgcttt
    27901 ttgcaaacgt gtcagataag caacacctgg tgtagagatc acacctagct ggaacacttc
    27961 gatacccacc gataaaagtc ctgaaatcag cgcttcttct aacatttgac ctgagattct
    28021 tgtatcccgc cctactaaca cgcgtgggcg ttttccttct tcttcatgct ggcttaggac
    28081 ataacctccg caccgtccca gcttaaatgc aagttctggc gtaagttcct tgttggcttc
    28141 accgcgtacg ccgtctgttc caaaatattt acccatagtt gtaaaattac tcctttaact
    28201 taattttctg aggaatttgt tctgctcatt tgtgttgatt cgcttgtttc tgatgtttct
    28261 tctgtacttg tggtcgagct gcttgtccca gattccgaac tggaagaaat ggttgttgtc
    28321 gatggttccg ttcctgaatc agcagatgaa atacttctac tcgtacttgt attttcttgt
    28381 gtccgactgc tcgtcgaagc agagctactg cttgacgttt gcaacacggg tgtaatctcc
    28441 acactaactg attcgggctt gatacttaac ccctcttcta ctggtatttc aattttacga
    28501 gttgttcgat gattgatacc tgagacattg atcggtacag caatactgtc accgatcgat
    28561 gcaagcaaat cgctagagcc gcttacttct gcttccagtt ttgaaaaact gaaatcatag
    28621 ctttctaccc cggcagctgg tgttccttgc tgtatcccat aaagtcgtac cgacttgctt
    28681 ggcttgatcg aatcagctct cactgttact tgcactggat cagagacgat acttaatact
    28741 tcccctgctg cattcagcgc ctgtattggg acctcactat taatcccatc atctgtgacc
    28801 atcgaagcgt ccacatcagc tactactcgt ttgatttctg ccaatgtttt gtcacctgta
    28861 gtgatagaga cttttttagg actaacggaa gtatcatcaa gttcatatcc agatggtgtg
    28921 aacgttgaag gaatcaacgt ttccacatcg aaatctttta ttaccttttt ctcaaccgtt
    28981 actgtaatag tcgatggttc gatctttgct gtgacagcac tgctcaaatt ttgaattttt
    29041 agcggaacct catgtgttcc ttcgcccagc ttagtgatat ctgctgtgac gcggaacatc
    29101 cgtgtatctt cgtttgcctc tgcattcaac tgaactcggt ttgcactgga aagtttgaca
    29161 gtcactgcat tttcatatcc atggatatag tagcgctttg aatcataaga aatcttgatt
    29221 ggcaccccag taactgtttg attatacgct tcatttccag aaagcgtatt tggaacggac
    29281 tggccatttg cattgaagta cagcgcaata ctgaacagca atgcaataaa actgtaaaga
    29341 atgcttgtcc gtttctcttt tgagatcatt tgcgatcccc tcccttagtc ataccgtcta
    29401 ggaaagattg aatcacgttt ttcttgtttt ttgttttctc ttcagcaatc agttctctac
    29461 gcaaaattgc caaatattct tgctgggata agccagccat cagttcatta tctaatgtaa
    29521 tgctgacatc cccagtttct tcagagacaa cgatggtaat cgcgtcgctg acttcgctta
    29581 taccgacagc tgcccggtgt cgagtcccga attcttttgg aatcaacata ctttctgata
    29641 gaggaagata ggcgcttgct actgcgatct ttccttcttt tacaataact gcaccgtcat
    29701 gcagcggtgt attaggaata aagatattga tcagcagctc tccagtgata tctgcatcta
    29761 atgcaattcc tgtctcaata tactcatcta atccagtatg ccgttcgata gtaattagcg
    29821 caccgatttt tcgcttggac atatattgga tggctttgtc aaaagacaag atcatcttct
    29881 catcttcctg ctgttcgctt tttgattgtt tgaaaagcga actgcgtcca agatgttcca
    29941 gtcctctccg gatttccggc tgaaaaatca cgatagcagc tatcaccccg tacgtaatga
    30001 cttggttcat cagccaagac aaggtgtgca gaccaatgat ttccgctacg attcggataa
    30061 caataaaaat agctacacct ttcagaagct gaatcgcttt tgtgcctcgc agcagttgga
    30121 tcagtttgta tacaagatac cagacaacca gaatatcaag tatgttcacc aaaaaattca
    30181 gagagaacaa gtcaccggaa aacatttgct gccaatagtc caaattaaaa agttccccga
    30241 tttgaaatga cataaaaagc ctctcttctc ttttgagatt tcctctctag tatatcatat
    30301 gttttaattt tagaggctga tctgctcgta tttttcttga gaaaaacgca taattttcag
    30361 gaaaattgca agtatgcgtt ttatttttct ctgcaataaa tatttttaaa cttcagagaa
    30421 ttattcatta tattttttct gttatttttc ctttttttct tttgtagctt gttccatttt
    30481 tttacgtcgt tctgctctgg cagctcttct ttcttctgct tcaaggtccg tcgttttttc
    30541 ttttctagtc ttaacgggta catcgataga ttcctctggt tcaagtcgtt tcttgatttt
    30601 ttctaattct cccgtcagtg cagcatagtt gtaaaaacgt gttttagcgt cttggatagt
    30661 cttttcaaat aaagcttttg caagatttgg atttgcgttc tctagcgagg aaaagcgaac
    30721 ttgtttcctc atgaaatcag gcatagcaga gaaatcaggt tttttgtagt ccaaagtcat
    30781 tgggttcttg tttttttcga ccattgcagg gttatatcga tataatgacc aatagccaga
    30841 agaaacagct tcttttgctt ctttaagcga ttctttcatt ccaccaagca aaccatgtgt
    30901 gatacaaggc gtataggcaa tgattaaaga aggtccagga tacttttctg cttcttcaaa
    30961 agcctttatc gtctgcattt gattggcacc tgaagcaatt tgcgccacat aaacatttcc
    31021 atatgtcatc gccatcattc ctagatcttt ctttgaagca tactttccac tagccgaaaa
    31081 tttagcgatt gccgaagctg gtgttgcttt tgaggtttga ccgccagtat tggaatagac
    31141 ttcgttatcc aaaacaagaa tattcacgtc tgctccgctg gcaagtacat gatcgatccc
    31201 gccaaaacca atgtcgtaag cccatccgtc tccaccaatc atccattggc tgttttttac
    31261 gaatagatcc tttctcttgt atatatcctc cagttcaggg acaattgatc gttcgctttc
    31321 gatcgcagct tgcagttttg ctgctctttg ctgcgttcct tcgctctcaa acatgtgtac
    31381 caaccagtct tccatcaatt ctcgtagttc ttctgatact tttggcaata cttctttgat
    31441 tgaacttgcc aaagcctcgc gacgagtctg tgccgctaga agcataccat aaccaaattc
    31501 agcattatct tccaataaag aatttgacca tgcaggccct tgaccacatt cattggtcgt
    31561 ataaggagaa gcaggagaag caccgcccca aatagaagaa cagcctgtcg cattcgcgat
    31621 catcattcga tcaccgaaca tttgtgtcaa taattttaca taaggtgttt cgccacagcc
    31681 tgagcaagcg cccgagaatt caagaagcgg ttgattgaat tgtgtagaca agacagtatt
    31741 ctttcctttg actggatttg ctttttgtct taatgtcatt gcaaaagccc aattcacagc
    31801 ttgttctttc tgttcttcat aaggcttcat cactaaagct ttttcttttg cgggacaagc
    31861 ctctacacac agaccacaac ctgtacagtc ttccactgaa acttggatac ggtattttac
    31921 gccgtctgcg cctcgcattt ctctcacgat aaatccttct ggcgcttctt ccatttcctc
    31981 ttcatctgct aaaaatggac ggatggcagc atgaggacaa acaaaggcac attcattaca
    32041 catcgtacag cgatcactaa tccactcagg tacttctaaa gcgacgcccc gcttttccat
    32101 agaagccgtt cctaaaggca tttcgccagt tgtcattcca tttgctacaa gtgtaccaac
    32161 agagagttga tttccttcct gtgcattcac tggttcaagt atttcttgta tataaccagt
    32221 gttcctttta ttgatttttt caggcatctc caacgttctc caatggtctg ggatcgcgac
    32281 ttgatgaagc agttcggtcg tccgatcgat tgcttgtatg tttttttcta cgatagtcat
    32341 tgatttatgt ccatagcttt tcagggcttc ttcttttagc agcggaagca cctcatcaaa
    32401 aggaatgatg tcagctaatt taaaaaaagc cgtttccatt gccgtattga tccggcgtcc
    32461 caaaccgact tcttgggcca atctcatggc attgatcgta tagaatctaa tgttattttc
    32521 agccaagtaa cgttttaatt ttaagggcag atgcgtttct aattgttcgt cgctccaaag
    32581 agtattcaat aaaaaaatgc cacctggctt caatcctttg accaagtcat agctatgcag
    32641 gtaagctggt gtgtgacagg caacaaggtc cgcatgctcg acaagatacg ctgaacgtat
    32701 cggcgtatct ccaaaacgaa gatgagagac agtcagaccg ccagattttt tcgaatcata
    32761 ataaaaatag ccttgcgcat atttatcggt gtgatctcca ataatcttga tagctgattt
    32821 atttgctcca actgttccgt cagatccaaa tccccaaaac ttggcctgga atgtttgcgg
    32881 ttctgtcaaa tccagacttt cctttggttc caaagattga taagtcacat catccacgat
    32941 ccctatggta aaccgttttt tgcgtatgct tgggtctttt ttcaattcat caaaaactgc
    33001 tgagatttgg tcgggagtca catctttaga ccccaatccg tagcgaccac caataacagc
    33061 cgggcgaagt tcagaatcat ataacgcact ttgaacgtct aataagagag gttctccacc
    33121 tgcccctggt tctttacttc gatcaagaac agcaattgtt tttactgtat gaggcaactt
    33181 ttgcacgaat gtttccactg gaaaaggacg ataaagatgg atattcaaaa aacctgtttt
    33241 ccgtccgttt gcattcaagt aatcaatcgt ttgttcaatc gtctgtgcaa ctgatcccat
    33301 agaaacaatg acttcttccg catcgtctgc tccgtaataa gtcaccaagt cataagaagt
    33361 tcctcgtaat cggttgatct ctttcatata tttttgaacg atttcaggta atttatcata
    33421 ataggggttg atcgtttccc gttgttgaaa atggatgtct ggattctggt tcgtaccact
    33481 aacagtcgga tgattgggat tcatccctcg tttacgaaat gaagctaatt tctcctgatt
    33541 gatcagagga gctaattctt catattccaa aacttcgatt ttttgaatct cgtgactcgt
    33601 acggaatcca tcaaagaaat tcaaaaaagg tacttctcct tcaatagaag caagatgggc
    33661 aacaggtgct aaatccatca cttcttgtac actgctttca gctaacatag caaatcctgt
    33721 ttgtcttgca gccatcacgt ctccgtgatc tccgaaaata ttcaacgcat ttgtcgtcac
    33781 tgcccgacta gcaacatgga aaacacttgg cagtagttcc ccagcaatct tgtacatatt
    33841 cggtatcatc aaaagcagcc cttgagaagc ggtatatgta gttgtcagtg caccagtttt
    33901 caatgatcca tggaccacac cagctgctcc tgcttcggat tgcatttcta ctacttttac
    33961 tggttgaccg aatacatttt cttttcctgc tgctgaccat tgatctacta attcagccat
    34021 ggtcgaactg ggtgttattg gatatattgc agcaatctcg gtaaatgcat aagaaatata
    34081 tgcggctgcc gtattgccat ccattgtttt catttttcgc atgattcatc atccttgttc
    34141 atattctctc ttattatctg ttccattata acgtaaaaca ttccattttt tcttttattt
    34201 ataaaaatat ttcacatatg tctatttgaa ttggtcatct aatttttaga caaacagtct
    34261 aaatcgttgc ctttttttgt cagacatgta taaactataa gcgaaagagg tgttttaaca
    34321 tggatatatc agtgattgat gcaacgaaaa caaatacaca aaaaggaatc ctttatggtt
    34381 catcgaatgc tcctaaaaaa atggtcgaat tcatcaacct atcttgtccg tattgccgac
    34441 aatggtttga agaatcttat gagctattag aagaagcagt ccaaagcggg caattgcagc
    34501 gagtgatcaa attgttcgat aaagaaaaag aaagcttgca gcgaggaaac gtgatgcacc
    34561 ggtatctcac aatcagcgat ggtcaaaaag cgatcaaaga gatcaaacaa atattcgata
    34621 ctcaagacga gtggaaacat ctttctctcc aagaagtagc ggattttgca gtagataaac
    34681 taaagctgac agaacaaaaa gacgaacagc tgagccaagc tgtcatcaac gaagctgagc
    34741 aagcacatat tcgatttgtt ccgactgtca tcttgggtaa agaaatcttt gatgaatcta
    34801 tttcaataga ggaattaaaa gaattgatcc aaacaaaata aaaaaataag gagcgtagga
    34861 caaaagtaaa gaacactttt gtctcacgct ctaaacacct ataaacggcg gaagcagaag
    34921 caactccttc ttatttcttg gagttaaacg cttctgtccc agcctcctta ttccgaataa
    34981 atggtgtcca aaagcttgca tctgccagat tatctcattt cttatgacaa gctgagcaaa
    35041 ttatctccac caaataattt attcatattt ttgacttgcg catactaact aattcttaaa
    35101 ttttcataca aaatttctca aattccctta acgagtaata tttatgtacg gtgattcaca
    35161 ctagtatccc aatcactttt taagttatcc cgatttcaat tctacttcaa aaatagttgc
    35221 ttttatgtat gctgttagtt gattagatgg tcgtttgttg agctaggtcg tttattttaa
    35281 acaagttgtt tctttagctt atacctatct cgtctaccaa acgcaagatg gcaaacacaa
    35341 atgcatacgc atctgtattt gccactttga ttcgtataaa gctaacaact cctaactcct
    35401 ctcatttaat agttgctctc ttttttattc agatacattt ttgctgatca cagcctagta
    35461 tttcaatggt tttgaacact aaaccaaatt gttccattac aacattcact ggctgatgaa
    35521 atggattaat agatttcgat tattcaaagc gattttctat tggtggattg tgttcccaac
    35581 taacaagacg gattccaaag tcattatata actcttcaag agttaaccct ttcctgttcc
    35641 caatagatgt atctctccca cgctcgatat aaaatatgga gtttcgaatg ccaagacctg
    35701 gcaaatcttt ccttgttaca gttacactgc tactaacttc cccatataaa atccagctcc
    35761 tccaaaatga taatatattt ttcgaccatc atctaactca tgtaacaata attgttgtgc
    35821 cctcttgtca ctcgccaaat gcaaacgcca cgtgcgatac catgccatgc tacctgcatc
    35881 tgcagaaaat ccatcaaata atgcaacaat tgtatcttct atcacaatcc tttccccatc
    35941 tacttcatat tctaatctaa aatcaaactc ccctcgggta atcgcaggtc ttggtggctt
    36001 aggacccaat attattctac ttaaaaccgc attcgttccc agatgaaaca cagctataac
    36061 aacaataatg attaatattt tgtttctatt tgataaattt ctcattattc gcaaatcacc
    36121 tctacattct cacatactag ttcgtaatac tcctttaata tcaaaatatc tactgatcgt
    36181 aataatattc gctatgaatt cctactactc gtataagaaa ggccaaatca tcagctttta
    36241 cttgctgatg atttggcttg tttctattta tcgtaattgt tttctaatca ccaaaattgt
    36301 taacaatcgg ttcagatatt tcccaattca ctagccttat attatattga tttaacaatt
    36361 cttcttcatt tattgtattt tgatcaagcg gaccaaattg ttctaataat tctttgtcat
    36421 gtaaaatatc ccttctagta atgcctcttt ccctttcaat gaaagaagca ctaggaaaag
    36481 tatgattata accattcaac ctatctccca tgtaataatt agcaggtcct ggaaaataaa
    36541 atatttgctt attatcacta acttctaaca gcaacactaa atcttctccg ctggctaaac
    36601 gacttgtcca tctacgatat ctccctatgc cttcgttcat tccaaatcca tcaaattcaa
    36661 ctattaacgt gtcttctatc acatgtaatt cttcattcaa ttcatactca agtctaaaag
    36721 gaaattctcc atatgtaatc tctggcaatg gtggtgctgg agttctccaa ataaatacaa
    36781 taactgtgaa tagaaaaaat ccaacgatcg atataaatgt tatgagacct gctcgaagta
    36841 aaacccgata taataaaaat gctgtatttc gctttgctat atctagaaaa ataaaaagta
    36901 ctgcaatcat aatgatagta aaagttgtaa aaaaacgcat ttttgccctc cctttataaa
    36961 catcgattct caaattctaa accaaatctt ggtagttcaa gttcaggtat aacgtattcc
    37021 aaccatacat ctcaattact atttatgaac ttatgattat cactgaataa atcactccat
    37081 ccccttgtta aaacttctac attaattaca cctggttgtt ttcgactagc taatccaatg
    37141 aacttatcaa ccatccttat ccaccaacca cgagaatctt gaccagaagt aagaagagca
    37201 gttctcaagg atgatcgagc agttccttcc agttttttaa ttaatcaggc cagttataga
    37261 taaatacttg atcttatcta tatcaggact tctatattaa gcaaaaattt atgtacaaaa
    37321 ctaaaatctt cattcagttg tctccccgct ttttatacga ttgtattaaa aacaatagaa
    37381 gcctttccaa attatgttac tccagtaaag atggaattat agtttgacgg aagaaaagca
    37441 agtataactt ttaaaaaaaa ctgatacatt cgcatctcct gcttcatgta tcagtttttt
    37501 ctttggatta aactgcttct tcacgcagtt tttccgcaaa ttcatttatt ttgcgaattc
    37561 ggtgattaat tcccgatttt gatatcgcac ctgagggaat catttcccct aattctttca
    37621 agctgacctc tggatgttga agccgaagtt ctgcgatttc ctgaagtttt tcaggaaggg
    37681 catgtagacc gacctttgct tcgatcaatt cgatgttttc gatttgttta gaagccgcat
    37741 caatcgtctt gttcagattt gctgtctcac aattgactag acgattgacc gaatttctca
    37801 tatcccgtac gattcgaaca tcttcaaatc ggagcattga gttggttgca ccaatcaatg
    37861 ttaagaaatc agcaattttt tctgctcctt ttaaataaga aatatagcca ttgcgccgtt
    37921 caagcgttcg agcatgtaga ccgtaataat ttaacatatc gcaaatgtct tggttatgct
    37981 gttcataaat agaaaatatt tccaaatgat aacggctcgt ttccggatta ttgactgaac
    38041 ctgaggccat aaaagcacca cgtaagtaag aacgcatttt ttgcgaattt cccataatct
    38101 cgtccgaaac gtgtccattg aacatcatac catccatgat atcaagatcc atcaacacat
    38161 cttttgtgcc ttgcttcaac cggacgatat agacattgtt cttttttaat ttcatttttt
    38221 tacgaacgag tagctcactt cgtacctgat aatgatcttt caaaagagaa tagatacgtc
    38281 tggcaattgc agcattttct gtttggacgt tcaaaataaa ctgctggttc acaataccta
    38341 aagagccgtt cattcgcagc aaagcagcta attccgcttt cgcatgttct cgatgaactt
    38401 ccaaaccagt tagttctttc ttcacatctg cagcaaatga catcctattc tcctcctttc
    38461 tccaacaata aattgcttaa tattttgaac cgaaaactaa acggaacaat tcttctacta
    38521 ctttgtctcc atcgtggaag acaccaccat ctttcaattc caaaaagtcg gtggaaatca
    38581 ctcgacatcc ttcatttctc aatccgttga agtcgtgtgc gacttgtact agatactcat
    38641 catagatctc tgggtccata taatcttcag gcactttttc cgtattgacc aatactgtat
    38701 cgataaaagg ctgattcaaa tgcttgtgta aaacacgtat atgatcggca tctgtgaaat
    38761 gttccgtttc ccctttttgg gtcatgatat tacagatata gacggtttca gcagttgtct
    38821 tgagcattgc ttcgccgatt tctggtatca ctaaatttgg aaggatactg gtgaataaac
    38881 ttccgggtcc caaaacgacc atgtcggcgt ccataattgc tgaaacgact tttcgagccg
    38941 ctttggcttc acttttatca tttgtgttgc agacatacac acggtcaatg gttttacggt
    39001 cgatcgcgat tttagattct cctactgcag tcgttccgtc tttaaagaca gcatgcaagg
    39061 tcaaaggagt ttctgaagaa ggataaacat gtccatctac atgcatcatt tttgctaata
    39121 attgaatcgc ctcataagtg cttccccgca tctcggaaac tgcggcaatg atcagattac
    39181 cgatcgtatg attggctaaa aactgatctt cctttttgaa acggtattgg aaaatatctt
    39241 catagaattg tggcatatcc gataacgcca ctaagacatt tctcaagtca ccaggaggag
    39301 ccatagcgat cgattctctg attgcaccgc tgcttccccc atcatctgca acagtcacta
    39361 ctgctgtgat atctgctcct tgatttcgca aacttttcag gataactggc agaccagtgc
    39421 caccgccgac cactacgatc tttggttttc ttatccggta ggttttcatt ttcacgaccg
    39481 gttcaccgtc tctttccttt tatccttgtc ccgatgtgtc acattgactt tatagttttt
    39541 ccctaaagca tttgccaaac gttcagtcaa tgccacagaa cggtgttgac cgcctgtaca
    39601 gccgattgca actgtcaagc tgctttttcc ttctttaatg tatccaggca atacagtttc
    39661 cagaagatcc aaaaatttat ggtagaatga ttgcgtttca tcaaaggaca tcacataatc
    39721 atagactggc tgatcttttc cggtcaatgg tcttagttcc gggatataat gagggttggg
    39781 caaaaaacgc acatccatca caatatccga atcgatcggc aacccgtatt taaaaccaaa
    39841 tgatacaaat tcgatccgaa atccttggtc tccctttgat ttgaatgact cattgatttt
    39901 ttcacgtaat tgtcgtggtg tcaatgtcgt cgtatcaatg atcacggaag cttgggcttt
    39961 caagtcgtct agtatcgccc gttctttacg tatcccttca gtgatcaaac cgtccatcgc
    40021 cattggatgt gctcgtcttg tttctttgta gcgagccact agttcttcgt ctgaagcatc
    40081 taaaaataag atagaagtgt cgatgaagtt cgtattttcg atttcgatca gcatgttttg
    40141 gatttcttca aagaaggaac gagaacgtaa atccactcct aaagccattt ttgtgacttt
    40201 gcctgattct ttgattaatt cccagaattt tggaatcaat cgaggcggca tattatcgat
    40261 acaaaaatag cccatatctt caaaactttg gatagctact gttttccctg caccgctcat
    40321 acctgttatg atgactaatt gcaaattatc tgtcataatt acgaactcct ctcacattgt
    40381 gcatagtaaa attatatcat tccgggcgta tcattaccag ttttcttttt cttttacaaa
    40441 aagatttgga ccaaatatct tttaggatat ttgccccaaa tccaattttt ttacttttcc
    40501 gatgctgtat ccaatgcctt gcttctttca gctagcgctc gttcaatcgt ccgatctgct
    40561 aaaatagatt gggcatcgat cactggataa tggttatctt cagcaaattc atgcatcaat
    40621 gacaattctg tgcaacctaa gataactttt tcacagttta ggcgctctac cgcttcttct
    40681 aagatttcgt aatatagctc ttgattcaaa taatccgatt ccttgatctc atgatagatc
    40741 agataattga ttttttcttg aagaacagta tcaggaatca ctgtttcgaa tccaagattt
    40801 ttgacttcgc gttcatagat tccagctttc atacttcctt ctgttcctag aatcgctact
    40861 ctccctgtcg tatgctgacg gacaagttca tttgctgctt ctcttggcat atgaaggata
    40921 ggaatatccg ttgccgcttg taattcttca aaaaagtagt gtgcggtgtt acaagtcaac
    40981 acaatgaagt tcggctgcaa taaattttgt ttctcaatat catccagcag aaacggcatt
    41041 ggattttctt ctgatcgatc taaaatataa gctgtacgat caggaactgt tgcatgattg
    41101 aataagacat aattcaaata ttcttgatct tttgtagctt tcgttcggtg gttgatcaag
    41161 cgaacaaaac tttctgtcgc catcgtgccc attccgccta aaatactgaa aaaattctcc
    41221 atgaactagc cttctttcac atgaaaatac tttttgaatc ttggaatata gttatggaac
    41281 atatatttca tcaacaacca gcgcttgatt gaccggtctt tttcataaaa cacagtagta
    41341 ccgtaacgat tttctttgat catttgctca gctagttttt tgtcttcatt ttcccgagca
    41401 tattctaaaa agattttttt gggcacaccc atccataatc ttgctttatc tgattgattc
    41461 gttccatagg tcgtttcaac aaagggtttg ttaaacactc gatcttctgt gacgaaacga
    41521 gccagattca agccgttcaa tgtcacaaag aaactgctac gaccttgtct caaattgatt
    41581 tcaaataatt tatattctcc atctctagga tcatacttca tatcgaaatt ggcaaagcct
    41641 gtatattcga ttttttccaa aaatgcctta atggtttgat agattttttc gttataatct
    41701 ggcatgatca caacgtaatt accaatcgat gctggtgtag gatcttctaa cagtggatga
    41761 ccaagacaca tcatccgaac ttgatgatct tcatctacat acgcatttag cacacgcata
    41821 ttactatcat cacccgggat aaaatcttgt acaatcattt cacttttata accggcttcg
    41881 tatatccggc ctaaaattaa atcgaactct tctctagtct ctaaaataaa agcttttttt
    41941 cttccttcaa attggacaga aagatactcc acactgtttg caggtttcaa agcaactggg
    42001 aattcaaaag gcaattcctg ttccaaatgt ccatttacta acatttcttc tctgacgatc
    42061 aatgttttag gatacggaag atcatattct tcacaaactt cataaaagct tactttattg
    42121 atcagtcttt caaataaaga ataatcaata tatggacaga taaaatattc tgacagctct
    42181 tgtttatgtt gggagatcaa ttctgcatat ccatcaccac aagcaatcaa aagatatttt
    42241 ttactcttat cagaatatct ttcttttgcc aaacgaagca tcgtctcgat aaacacaggg
    42301 tctttatcaa atcctggaat aacttctaca ttgacaattt tactgtagcg ggtaggggct
    42361 aactgatccg aagcatatgc ttggcagatt ttgccgtatg cttcattaaa agaacgtgcc
    42421 ataccataaa cgttcatgtc gcttcctaat aatataggga taaattcttc attttcaata
    42481 ctgttcatca ttatctctca cttactcata atctcttgtt tttcttttcc aactacacaa
    42541 ggaatatcat accataaaga aaaaagcaat caaaggaaac tcctccgatt gctcaattct
    42601 tttttgaacg gattgaactt ataggaagtt tttgtctata ccaatcagtg tagaaagaac
    42661 taccatgtaa tgattctaga acactgatat taataaaaca agcaaaaatt cattttttta
    42721 tgttttttta actatctcag ctatctatcc tctttatacc attatttttt tcaaatagtg
    42781 acctgtataa ctttctttta cgttaatgat ttcttctggt gttccagtcg caaggatcgt
    42841 tcctccacct tctccacctt ctggtcctaa atcaatgata taatctgctg ttttgattac
    42901 atctagattg tgttcaatca ctaaaactgt gttaccagca tctactaatc tttgtaatac
    42961 atgcaacaag cgggcgatgt catcgctatg aagtcctgtc gttggttcat ctagtatata
    43021 gaaattcttt ccattagaga ttttgtgcaa ttcactggca agtttcatcc gttgtgcctc
    43081 accaccggac aatgtcgttg ctggttgccc catcgtcaca taacctaagc caacatcaac
    43141 aatcgtttgc agtttgcgat gaatctttgg aatgtgcttg aagaattcta cagcatcttc
    43201 tactgtcatt tccaaaatat cagcaatgct ttttcctttg taatgcactt ctaatgtttc
    43261 agagttatat cgtttgccat gacatacttc acaaggaaca tagacatcag gcaaaaagtg
    43321 catttcgatc ttaataattc catccccgcg acaagcttca caacgaccgc cttttacgtt
    43381 gaaactaaaa cgccctttct tataaccccg catttttgcc tcgttcgttt gagcaaataa
    43441 cccacggata tcatcaaata cacttgtata agtcgctgga ttacttctcg gcgtccggcc
    43501 gattgggctt tgatcgatat cgatgatctt ttcgatactt tcgtagccgg aaattgtctt
    43561 gaatttacct ggcttagcag aattcttatt taatttttgc gctaacgatt tctttaagat
    43621 actattgacc aatgtactct ttccagaacc agacacacct gtgactgcta caaattctcc
    43681 taatggaaat tcaacactaa tatttttcag attgttttct gaagcaccag tgatcttgat
    43741 tgctttccca ttacctttac ggcgttcttt tggtacaggg attgattttt tccctgaaag
    43801 atatttccct gtcaaagaat tttcatcatt agctacttct tcaggagtgc ctgcagccac
    43861 gatttgtccg ccttgttctc cggccccagg tccgacgtca atcagataat ctgctgccca
    43921 catcgtatct tcatcatgtt cgactacaac gagggtgttg ccaagatcac gcattttctt
    43981 taatgagcca atcagtcgat cgttgtcgcg ttgatgcaat ccgatcgatg gttcatctaa
    44041 aatatacaaa actccagaaa gattcgatcc aatttgtgta gccaatctga ttcgctgcgc
    44101 ttctccccca gataatgttc cggaagcgcg actcaaagtt agatagtcta gtcccacatt
    44161 ttccaagaat gaaagtctgt catttacttc ttttaaaatc ggtttggcaa ttactttctc
    44221 ttgttcagat aacgttaagt ttgagaagaa atctactgct ttttgaatag acaactcatt
    44281 tgtttgcccg atattcgttc cattgatttg aacagataga gcttggggat tcaatcgata
    44341 acctttacat gtctgacaag ttaattctgt catataaaga cgcatttgct cacgcgtgaa
    44401 atcactgttc gtatcatgat aacgacgctc gatattcttc aatacccctt cgaaagtcgt
    44461 ttctacatcg cgaacgccac caaaatcatt ttcataatgg aaatggaaaa gatcatctgt
    44521 cccattcaag atgatatcct gatgctcttc cggtaattct tcgaatggtg tatctaaatc
    44581 gataccgaaa ctttcacaag cctgcgctaa catttgagga taatactgag agctgattgg
    44641 attccatgga acgatagcac cttgactaag tgtcttcgtt ctatctggaa tcactaaatc
    44701 ttgatcgact tctaatttga cacctaaacc atcacagtct ggacaagctc caaaaggcgc
    44761 attgaatgag aacagtcttg gttctagttc gccaacagta aatccgcaat aaggacaggc
    44821 atagtgttcg ctaaacaaca tttcttcttc accgatcacg tcaaccagag catagccgtc
    44881 tgccaatcgc agagccgcct ctaaagaatc aaatagacga gaacgaatcc cttctttcac
    44941 aatgatccgg tcgatgacga tcgcgatatc atgttttttg tttttctcca gctcaggcac
    45001 ttcacttaaa tcatagatct caccatcgac tcgaacgcgg acgtatccct ctttttggat
    45061 tcgttcgaat atttttttat gttgtccttt tttctttacc acgatcggtg ccaacacttg
    45121 gatctttgtg cgctcaggca aagccattac ttgatctgcc atttgatcta ctgattgact
    45181 ggtaatctcg atatgatcgt tgggacaaat cggatgtcct acacgtgcaa acaacaagcg
    45241 taaatagtca ttgatttccg tcacagtacc tactgtcgac cgaggatttt tacttgttgt
    45301 tttctgatca atagaaatcg ccggactcaa tccgtcgatg ctatctacgt ccggcttatc
    45361 catttgtcct aaaaactgac gagcataagc agaaaggctc tctacgtatc tccgctgccc
    45421 ttcagcgtac agcgtatcaa atgctaggga actttttcca gaaccggaca aacctgtaac
    45481 gaccacgaat ttatctcgtg gaatcgttac atctatattt ttcaagttat gggcacgtgc
    45541 accgtgaatc gtaattttat cgttagccat gttgtcctcc tactttgaag cttttaattc
    45601 taaaatcata tctcgcacat tagcggctgt ttcaaaatcc aatgctttcg ccgcattttt
    45661 catttctttt tctaatttca tcaataacgt atctttttct tctttcgtca tttcttcata
    45721 cgagacttgt accgcttctt ttgtatcatc ttccgattct ttcgtaatag aaatcaaatc
    45781 tcggatttct ttaatgatcg tttttggaac gatcccatgt tcttcattgt acttctgctg
    45841 aatcgtacgg cgtcttgatg tttcatccat cgctagacgc atagaatctg ttactttgtc
    45901 tgcgtacatg attactttac cttcttcatt ccgagcagct cgtccaatcg tttggactaa
    45961 ggaacgttca ctacgtaaaa agccttcttt atccgcatcc aagatagcaa caagggaaac
    46021 ttcaggtacg tctaatcctt cacgaagcaa attgattcca actaacacat caaattcacc
    46081 taatcgaaga tctcgaatga tttctgttcg ttccagcgtt ttgatatcac tatgcaaata
    46141 tttgactttg atccctaatt ctttgaaata atctgtgagg tcttctgcca tttttttcgt
    46201 caatgtcgtt acaaacaccc gctggtcttt ttcgactcgt tcatttattt cgcctactag
    46261 atcatcgatt tgtcccatga ttggacgaac ttcgatcact gggtcaagca gccctgtcgg
    46321 acggatgatt tgttggataa cggtatctgt ttgttcatgt tcatatggtc ctggcgtcgc
    46381 agagacataa atgatctgat tgacatgttt ttcaaactct tctaaccgaa gtggccgatt
    46441 gtctaaagca gatggcaaac ggaaaccgta atctactagc atctgttttc tcgctcggtc
    46501 accattatac attcctctga cttgaggcat ggttacgtgc gattcgtccg ccacgatcaa
    46561 aaaatcttca ggaaagaaat ccaatagcgt ataaggcggt tcaccttctt tacgtccgtc
    46621 catatgccga gaataatttt caattcccga cgtgtagccc atttctaaca tcatttcaat
    46681 atcgtaattg gttcgctgtt ctaaacgttg agcttccaga agtttgtttt catttcgcaa
    46741 gacagttaaa cgctgttcta attccgcttt gatattcgct acggcatgct ccatatgttc
    46801 atcattcgtc acaaagtgag tcgccgggaa gattgccacg tgttccgttt ctcctaaaac
    46861 ttcacctgtc agtgcattga cttctcggat acgttcgacc tcatctccaa aaaactccac
    46921 acgtaaggca cgttcatctc ttgaagccgg aaaaatctcc acgacatcac cgcgcactcg
    46981 aaaacgaccg cgctgaaaat ctatatcatt tctttcgaat tggatactga ctaagtcacg
    47041 aatcaactga ttgcgatcta gttctgctcc ctgtcgaatc gaaactactt gtttttggta
    47101 ctcaaaaggc gaacctaatc caaaaataca tgaaacggat gcaatgacga tcacatcatt
    47161 tctttctaat aatgaactag tagccgaatg tcgtaatttg tcgatctcat catttacact
    47221 tgaatctttt tcgatatacg tatcgcttga aggcacataa gcttcaggct gataataatc
    47281 ataataagaa acaaaatatt caacagcatt gttagggaaa aattccttga attccccgta
    47341 cagctgacca gccaatgttt tgttatgggc aataattagt gttggtttat tcactttctc
    47401 aataagattg gaaatcgtat atgttttccc tgttccagtc gcacctaata agatttgtgc
    47461 ttttttcccg ccgactacgc catccactaa ttggttaatc gcttcaggct gatcaccagc
    47521 cggttggtat ttcgagacaa gctcaaagtg tcgggaggta tctctctcaa tcattcttcg
    47581 tcctcctttt cattcattcc ttttcatttt acgaccaata aaaagaaaag gaaagcaaag
    47641 gcattcctta ctaaaaaatt ataccacacc gaacatactt tcgccacttt tttatcttat
    47701 tatgcatgtt acgttttata acataaaatg ttagaaactc gcattttttt cattttttcg
    47761 agcttacagt cttgtctgat tcagcacttt tcgcctataa taataaaata ttggaaattt
    47821 aggaggttga ttatgaaaag aaagcattta tttcactcat ttgttttctt aatgacagga
    47881 cttgtgacac ttgcgtttgg acatgttgca caagctgaca acactacaac ggcagagtca
    47941 agcacaagcg agacaatgca aaaaatagag cccaaaaaag acgtatacgt aattgccagt
    48001 gactctgctt ttgctccatt tgaatttcaa aacgcaaagg gcgagtacga aggcatcgat
    48061 gtaaaattga tggaaaacat cgccaaactg caaggattta acatccgaat ggactaccgt
    48121 ggtttctctg ctgctttgca agctttggaa tcaggacaag cagacggaat gattgccgga
    48181 atgactgtaa cagatgaacg aaagaaaagc tatgattttt ctgattctta ctttgatagc
    48241 gggatccaat tagctgtcaa aaaaggagat acttcgatca agtcttatga agatttgaaa
    48301 ggaaaaacag tcggagcaaa agttggtacc gaaagtgctg aatttttaag cgaccatgaa
    48361 tctgaatatg gctattctat caaatatttt gatgctgctg atcaattgta cgacgggtta
    48421 aaagttggcg caatcgatgc aatgatggat gattatccgg taatcggtta tgcgatcaaa
    48481 caaggacaag aattggaaac accgatcaaa aaagaatctg gcggaaaata tgcatttgcc
    48541 gttaaaaaag gacaaaatcc tgagcttctt aatatgttca atgaaggatt gaaagaatta
    48601 aaaagaacag gcgaatacga taagattatt aaagaatatg tagcggatgg ttcagaaact
    48661 tccagtgagt cttccactgc tgatgaatca acatttcttg gacttatcca aaacaactat
    48721 caagcattgt tgaaaggact ttggagaaca attctcctaa ctttgatctc ctttgctttg
    48781 gctatagtaa tcggtgtgat ttttggatta ttcagtgtag caccaatacg cgctcttcgc
    48841 acaattgcta gtatttatgt cgatatcatc cgaggaattc caatgatggt tcttgcgttc
    48901 tttattttct ttgggttgcc tggtatcgtt ggatttacga ttcctgactt ccttgctggt
    48961 gttatcacct tgactcttaa cgcaagtgct tatatcgcag agattgttcg aggcgggatc
    49021 aacgccgttc ctgtcggaca aatggaagct tccagaagtt taggtctttc ttataatcgg
    49081 acaatgcaaa aaatcatttt gccgcaagcg atacgcatca tgatcccatc attcgtcaat
    49141 cagttcgtta tctcattaaa agacacaacg atcatttccg caatcggtgt agtcgaattg
    49201 ctgcaaactg gtaagatcat tgttgcacgt acaacacaaa gtacgtatgt ttacttgatc
    49261 attgcgatca tgtacttgat tttgatcaca gcattgacaa aattagcaaa agttttagaa
    49321 aagaaggtga agtaagatgg cagaaaaaat cttagttgag catttagtca aaaaatacgg
    49381 cgataacaca gtattaaacg acatcaatgt gtccatcaac gaaggagatg tcgtctgtat
    49441 cattggccct tcaggttcag gaaaaagtac atttttgcgt tgcttgaatc gtttagaaga
    49501 accttctgac ggtgaaatta ttattgacgg cgcccacttg atggataaaa gcacagatat
    49561 caacttggtg agacaacata tcggaatggt attccagcac tttaacctat tccctcatct
    49621 ttctattttg gaaaacatca ttttagcacc gatggacctg aagaaagaat ctagagaaga
    49681 agcagagaaa aaagcaatca aattgctgca gacagttggt ctagaagata aaaaagatat
    49741 gtatcctgaa atgctttccg gtggacaaaa gcagcgtgtg gctattgctc gtgctctagc
    49801 gatgaaccct gacatcatgc tttttgatga gcctacatct gcactcgacc ccgaaatggt
    49861 cggtgatgtc ttgaacgtca tgaaaaagtt agcagaacaa ggtatgacga tggttatcgt
    49921 tacgcacgaa atgggcttcg ctaaagaagt ggccaatcgt gtcatgttca ttgacgacgg
    49981 aaacttttta gaagacggaa cgcctcaaca aatctttgaa aatccgcaaa atgaacggac
    50041 aaaagatttc ttgaataaag tattaaatat ttaataaaaa ccaaaaatgc ccggtcgctt
    50101 catgacgacc gggcattttt agtttcttgt tttttcactt aactgtacca gccgcatcgc
    50161 ttgttctcct gcacaaacaa gcaatcgctc tacctgttcc atcgcataag aaagtaccat
    50221 cggttcattg acgatatcaa gtacatagtc gataccacct tcagaaacta tgatgattat
    50281 cttattctaa agctggcttt tttgttggta caaacatgac aactacaaaa aaaccaggcg
    50341 aacgtatgat tgttcgtctg gtttttaatt attaatgact tagcgttttt actagaaata
    50401 gaaaatttgg gcaagtctac tttatatttt tactagaaaa actacttccg ctttttcccg
    50461 ccaaaagcat ctttaaactt atcgaagaaa ccgtcttctt gctgttcttc aactttgatg
    50521 ccgccagctt cagcgaatgc acgtaatgct tctctttgtt gttcatttag atttttcggt
    50581 gtgatcagtt ttactttgac atgttggtcg cctgttgcac caccacgtaa cttcggagcg
    50641 ccttttccac gtaaacggaa gttcgtacct gtctgtgttc cagcagggat cttcaatttc
    50701 acatctccat ggacagttgg tacttggact tcatccccca aagctgcttg tacaaaactt
    50761 aaaggcaatt catagtaaat ttcagaacct tcacgatcaa agatatcact ttcttctaca
    50821 cgaaaaacca catacaaatc accaaatggt ccgccgtttt ctccagcttc tccttgacca
    50881 gctaaacgca tttgttgtcc ttcttctaca ccagctggta cattcacttt aactgaatgt
    50941 gctttcttct catgtcctga gccatgacag gttggacaag gttctttgat ttctttccct
    51001 gtgccatgac aaacatcaca agtttgacgg ctcatcactc gtccaagtgg cgtttggcgt
    51061 tctacattga tcgtacctgc accatgacat ttatgacaag tagttggttg tgtgcctggt
    51121 tttgcaccgt ttccaccaca agtatgacag atttcttccc gattatactt gatttctttt
    51181 tctacaccaa aaatcgcttc ttcaaaagac aagtcgaccg tatattgcaa atcagcacct
    51241 tgacgaggcg catttggatc gactgaccga ccgcctcctc caaagaaaga gtcgaagata
    51301 tcttcaaaac caccgaagcc gccaccagag aagccgccga atccaccaaa tccgccacca
    51361 gctccaccag caccgtaatt tggatctgtg cctgcatgcc cgtattggtc gtatgcagcg
    51421 cgtttttgcg ggtcacttaa aatctcatat gcttctgata cttctttgaa tttttcttcc
    51481 gcatcaggtt ctttattgat gtcaggatgg tattttttcg aaagcttacg ataagctttc
    51541 tttatttcat cttctgatgc tccttttgag agccctaaga cttcataata atcacgtttt
    51601 gttgccatag gctttcctcc tattggttct catcattttc acgtcgcttg ttatcatatc
    51661 atattttgtt tgaaacaaaa accgatactt caaactattt ttcaaaagaa aaagccaaag
    51721 tagcaacttt ggccttctct cgaaattcag tgaactgatt atttatcgtc gccatcgact
    51781 tcttcaaaat cagcatcaac gacatcatct gctccgcctt gagctgcttc tggattttct
    51841 tgagcttgtt gttgtgcagc ttgttcgtat agtttaacag tcaagttttg aacgatttcg
    51901 ttcaatgcat cgcgtttagt tttcatttcc tcgatgttgt ttgcttcaac agcggctttt
    51961 aattcgtcac gagctgtttc tgcttttttc acttcttctt cgtccacttt gccttctaat
    52021 tctttcaatg ttttgtccac agagaatagc aatgcgtcta catcattacg taggtcaact
    52081 tcctctttac gagctttatc tgcttcagcg tttgcttctg catctttcac catacgttcg
    52141 atttcttcgt ctgttagacc tgaagaagat ttgatcgtga ttttttgttc tttttgtgta
    52201 cctagatctt tcgcagatac atttacaatc ccgtttttat caatatcgaa tgttacttcg
    52261 atttgtggaa taccacgagg agctgctgga atatctgtca attggaatct tcctagagtt
    52321 ttgttgtcag cagccattgg gcgttcacct tgtaatacat ggatgtctac tgctggttga
    52381 ttatctgccg cagttgagaa tacttgtgat ttacttgttg gaatcgttgt attgcggtca
    52441 atcaatttag tgaacactcc acccattgtt tcgataccta atgacaatgg tgtaacgtca
    52501 agtaaaacaa catctttcac atcaccagtg atcacgccac cttggatagc agcacccata
    52561 gcaactactt catcagggtt aactgatttg tttggttctt ttcctgtttc tttacgtact
    52621 gcttctacaa ctgcagggat acgagtagat ccaccgacta aaataacttc gtcgatttct
    52681 gattgtgaca gacctgcatc ttttaacgct tgacgtactg gtacttttgt acgttctact
    52741 aagtcagctg ttaattcatc aaattttgca cgtgtcaatg tcatttccaa atgcaatggt
    52801 ccagattctc ctgctgtgat aaatggcaag ctgatttgtg tgcttgatac gccagataaa
    52861 tcttttttcg ctttttcagc agcgtctttc aagcgttgta aagccatttt gtcttgagac
    52921 aagtcaatgc tgttttcttt tttgaattct gctaccatgt agtcgatgat tttgttatca
    52981 aagtcgtccc cacctagatg gttgtcgcca gctgttgaca atacatcaaa gacaccgtct
    53041 cctagttcaa ggatagatac gtcaaaagta ccgccaccaa ggtcgaatac taagattttt
    53101 tcgtcgcgat ctgttttatc taaaccatag gcaagagcag ctgcagttgg ttcattgacg
    53161 atacgttcta cttctagacc agcgatctta ccagcatctt ttgttgcttg acgttgtgca
    53221 tcattaaagt aagctggcac agtgataact gctttttcga ctttttcacc taaatagtct
    53281 tctgcgaatc ctttgatata ttgaaggatc attgctgaga tttcttgtgg tgtatatgat
    53341 ttaccttcta catctacttt gtaacctgct tcaccgatat ggcgtttgat tgatgaaatc
    53401 gtatttgggt ttgtcacagc ttgacgtttt gcaacttccc ctacttggat ttctccattt
    53461 ttgaatgata caacagaagg tgttgtacgg tttccttctg ggttagcgat gatttttgct
    53521 tcgtttcctt ccaatactgc tactgcagag ttagtcgtac ctaagtcaat accgataatt
    53581 ttactcataa ttaacgtctc cttctttaat tgaaagtgta agttttatat ccgcacaatt
    53641 attgtgcaac aatgaccata gttggtctta acacgcgatc atgtaatttg tagccttctt
    53701 gtagtacttc tacaatcgta tcggctggtg tatcttcagt cgctggaaca gtttgtactg
    53761 cttgatgaag attaggatca aaggcttctc ctttagcagg gattttttca attccttctt
    53821 cttccagtgc gttacgcaaa ctttccaaga ccatttccac gccttttttc aaacctgccc
    53881 cttgatcatc tgacacttct gtggctaatg cacgttccag gttgtcaatt gatggaagta
    53941 attttttggc taaatcttgt gaacggtatt tttgtaattg ctcacgctca ttttttcctc
    54001 gatttgccat atttgcgatt tcagcacgag cccgcaagta tttatcttcc atttcttcta
    54061 actcagcttt taatttcgct gtttcgaatt cttccgcttc agcttctgaa atacccgaat
    54121 cttctgcagc ttcgacatcg atttccggtt ctggctgagc atctgtcatt tctttatcta
    54181 gttcttcttg attttctttc acgatacagt cttcctttca ttattcagtc agctgtttga
    54241 ttgctcttac taagaaagag agaacgatca gctgcaaata gcttcgttat tcacattacg
    54301 agtttgacaa gtcaagcgag cggtagtaat cagcaagttt agctgctagt tctcttcgat
    54361 aaacatcgac tagaccgaac atccgagaat aaggcatact agtaggccct aacaaggcta
    54421 ttgtacctct tccatgacca tctatctcgt aacttgcttg aatcatactc atattctgca
    54481 ataaatcatt gcctaattca gcaccaatct tgatatgaat attgctatcc atcggagtga
    54541 tcatttgtgt aagtccgtct gagtctttca taaaagaaaa catcgatttg aactgatcaa
    54601 gatcttgacg gggctcataa tccaagagat tcatttgtcc actgacataa accttttctt
    54661 caaaaacatg accaagaacg gtgtcaaata actgagacat cccttctgtc gtctggaaat
    54721 atttatgaag aatcatcgga atctccgtac gaagtttatg gtacaccgtc atcagaggat
    54781 ctccgactag acggtcgttt acaatctgta ccattttttc tagttcctga cttcccatat
    54841 attcgggaag agtgaacact tggctttcta cattccccat atctgttacg acgatagcaa
    54901 taatctgtcg attattcaag ggtacgatac gaaagccagt cagtcggcgg tcttttattt
    54961 caggtcccaa tgaaaaagtc gtatagcttg tcagctcaga taatatctca gcagattgct
    55021 taataatctc attgatttca tgaaattctc tgcctagaga ctgacgaatc agcagcaaat
    55081 catcttctgc tacgcgagca ggttttaaca aatgatccac gtaataacga tagcctaaag
    55141 cagatggaat ccgcccagaa gaagagtgag tcttcaacag caatccttca tcttctaatg
    55201 ctttcatatc attgcgaatc gttgctgagc tggccttgac tccctcagac attaatgttt
    55261 tggaaccaac gggcacgcca ctactcgtat agtgttggat gatcagacgt aaaatgtcgt
    55321 tttgtcgctt tgttaacatc ttcctcacct ctcattagca ctcatatatt ctaagtgcta
    55381 attcacttat aaatatagca agaagccctt ctcctgtcaa gagaaagact ccatttttta
    55441 gcactctaaa cacaagagtg ctaattctaa ataattgatg taaatccagt tatatcaata
    55501 cttcaatacc tcattgtcaa actttctaaa ctttttcttt tcaagtttcg ataaaaaaca
    55561 aatattcttc aaactatttt tcaaataaaa agcgctcaaa cacattgttc cccaaaaaag
    55621 tccctcttgg tgtcaaataa acacggtctt cttcattaac aagtaaccct tcttgctcta
    55681 attcccttag cacatcaccg tacaccgatt caattgtttt ttgatagcga tcatagaaat
    55741 gttttttagt aatccctgtt ttttttctta gtcctaagaa catttcttct tctatttgat
    55801 tttttcgtgt caatttttct tcttccaata ccgggcgttc atttgctcgt aatgggcgta
    55861 aatagtgttg gattggtcct ttgttgcggt aacgaatatc tccaagataa ccgctagcac
    55921 cagctccaaa cccaaaatag tggtcattgt tccagtacat gaggttatgt tgagattcat
    55981 gtccggagag cccaaagtta cttatttcat attggtgacg tccatgcttt tccattgctt
    56041 caatcgtctc ttcaaacatt ctggtttccg tttcctgatc aggcagttcg agtcttcctt
    56101 gtcgtaccca gttcatgaac attgttttgt tttcgaggat caatgagtac aaagaatagt
    56161 gaggcagatc caaagccaaa gctttttcca aagtatcccg atatccttct agtgtttgtc
    56221 ccggtaatgc ataaatcaaa tcgatgctta cattggtaaa attttctgct tctaaaaatt
    56281 gcattgtttg atacacatct tctgcagtat gtttacgtcc aatttttttc aataagcgat
    56341 tgtcaaatgt ctgcactccc atggataaac gattgacgcc atagtttttc atcacttgaa
    56401 gtttttcacg ggtcaaatca ccaggattcg cttctacagt aaactcatta ccattttgaa
    56461 aaggcaggat ctctctagca cctgataata gtcgatcaag ttgtttagca gataaagaag
    56521 ttggtgttcc gcctcctaca taaagtgttt ccaaattcgc tgtaggatga ctttccagca
    56581 ttaatctcat ttcattcagc agcatttcca catactcatc tactggctgc ccttctaaaa
    56641 aaactttatt aaagtcacag taatagcaga tatgctcgca aaatgggata tgaatgtacg
    56701 cagaaacctt gttttctgcg ggatttattg tttctatcat tgaaattctt tctccttacg
    56761 tcgaaaagtc gtgcctgttt tcgaccttct taaaatcgcg ttcaagcacc aactcattga
    56821 aataagccgc atatttagaa tcaaggaaac ctagctctaa aaatgcttgc ttattgtcat
    56881 cggagctaca cggtgctttt acagcctctc gataaacggt aatcgcaaag ctgaccttcg
    56941 gcattaagtc aaaatctgca aaaatatgaa aagctatttt cacagattcc tccttaagtg
    57001 ctcagaccac aacgctttgc ttacaacctc tcatatacgc atactaaacg tatttggcga
    57061 acaaatccac taaaaaatcc aagaatcgac ttcttggatg atttttttac actcatgatt
    57121 cttcctaaac aattttgtcc ttattttatt cataaaaaaa tctagtcaaa tctctcactt
    57181 caagagtttt aactagattc caattattat ttttttgtaa aaataaacag tctcttaatc
    57241 atagacattt cttcggtgcc ctacttgaat agcgataaca acgaattgat tatcttctat
    57301 ctctaccaat acacgtattt gccaatcaga gctgcttctg aatttcgggc gtgaatttta
    57361 aacggcaggt cattccagcc caccaaattc attaaggatt cttccatgaa tactgttgtt
    57421 ttcccacttc ttatccaatg tttatgggca atttcagccg tttgacgatt gtattcatct
    57481 tctagttgtt ccatcgaata gttttttaga agttcagata aagtaatccc ataaaattca
    57541 gccatataag aaagccattc ttttttggcg tcacttacac gaaccgtaat catagcccta
    57601 taattgcctc tcttaaagaa tctcatgcat ttcctgatgt gattttagaa aaatttactt
    57661 gctaaaaaac tgtgaaaatg taggagctag catccttgta gtaaatgatc gagctcttta
    57721 ttatacatta aaaaagttca gaaattttga tgaagtagcc aactactttt tcatgagtaa
    57781 agcaacacta gaaaaagaat cctccagtac ttagaattta ctggaggatg tacttttgaa
    57841 gaagcctata ggttatttaa aaaatattac tacaggaagg aacgagaatt acttcgttac
    57901 ttataataga acttagtctt atatagaagg catagctcac attagcttat ttgtcctata
    57961 aaaataaatt acggtatttt agaaaagcta ttttctcttt tttcaacgat cttcagcaat
    58021 ttttctttat cgtcaggtaa ctcaagttca tgaattctag catgacaatt gggacataac
    58081 gcgatacagt tttcaatcac atcttttcca ccttgcgaca aatattctat atgatgacaa
    58141 tgtaaataag gtacaccgtc ttttataaat ggcccttttt cttggcaaag ttgacaaata
    58201 ccttttgcaa gtcgtttaac atattcagat acgaagggat tacgtttata tatttttgtt
    58261 tttgagaagc aaaactcctc ttcgttaaca tattttgcag ccattttttt attataatta
    58321 ctaacttttc ttgcttcttc ctctaattta gcattagata aattacgaat atgtctagtt
    58381 tgattttctt cctggttata tatctttatc ttcaatcaat tgctcttgat ttattaaagc
    58441 taatggaaat ttatatactt ttctgctgtt gcccgaacta tctttttcat taacagtata
    58501 tatttgtcct gctaaatata cttctcccag atatgtgtgt tcttttggtt taaatgtttc
    58561 aaataaatga atctttacaa aattactttt tgaattggct aaaactttat tttgattctt
    58621 atccaatact tgatcccctt ttagccccat accggtatat tgtaaaatac catttaacca
    58681 cttatcttta taaacattac ttcctgtttg atcactaaac agtacaagag tattagtttg
    58741 atgagatctt ctcattccac cctgtttgga acatttaaac ttctctgaaa tttctttgtt
    58801 agtatatact ctaccaactt ctaactcacc taatatgttt ttagaccaat tttctcgcca
    58861 tgtaataatc ttatcaagat taaacatttc tccctctttt ggcatgccat ttctaattaa
    58921 attagctaat acaccagtag aaatatctaa tttttttagt aattctttct tagtaatcaa
    58981 tgttggattc ataacaatgc agctcctaat gatatcaata taattgcatt agataacttg
    59041 aaaaatcgaa aaaaactcat tttgtgtcaa gttatctgta atatataaaa atatcattat
    59101 tatacctcat ctatgtgaat ttttactatt cttaccttag catattcttt ataggtatat
    59161 cagagctaat caaactaaaa aatacccgaa gtcttcttat gtaaaaacac cggttattac
    59221 ttaaatatga cttaggtaaa acaatgagtg atccaattat aaaattttat ggcgaataat
    59281 ttagtaagcg ctacatattg aatgatttag aaattttgaa aaagtagcta gttcctttta
    59341 taccagaaaa gtaaacctaa taaaaaacac aactaatttt tagctgtgtt ttttaagtta
    59401 caataattat ctatttaata gtcttaattc attaaaataa aaaactcaac tttacaagga
    59461 tatggtttaa aaaatttatt tatccaaccc aactagtttt cgctgcttac gatttgcttc
    59521 atctgctacg taattcatta ctgttttaaa ttctttcgct gaggcgtttt ctgataaatc
    59581 agcgatactt ttattatact tcttcacgat ttgttgtact tgttctttct cagtcatgta
    59641 attcctcctc caactctttt gaagtatatt gtattggtag tactaattga atattatctg
    59701 ctgcataatg cacttcagaa atgtcgtttt gataatcctt aatcattatg tgaaggacta
    59761 cttcaggatg tctatttttg actttttcaa tattctctct ggacttaaaa aacgcattga
    59821 taaacatttc ttttggcaca tgacgtcctt cagctagttc acgttttcga gtgaaatccc
    59881 aggcaacttt gggatcttgg taaacataga aaatcgtaac gcgaaagtta tttttaaggg
    59941 ctcgaataat atttttctct gcactaagga tagcaaaagt atcctctagt atgaaagaat
    60001 agccatgttc cagtacatat tttaatgatt gttcaactaa ccaagaagaa gctttctgaa
    60061 aaacacttga gttctttcca ttgtattctg gaaattgtgc tctaaaatag tccgcatcaa
    60121 tcacaacatg gttgtcataa ttttaagcta aacctagtgc aacctctgtt ttacctgctc
    60181 ctgggcttcc agccatgaat accgcatctt tttcatcatc agggattttt cccttgatga
    60241 ttgtttcaat aaatttatct ttattgaccc tagcgtaatc taaatacttg tctttaggtt
    60301 ccaagattgc accttctttc cttcttctat attcatacta attatacgat atttatataa
    60361 aaaatataac ggtcatttta accatattaa catttagtca cagtaatagc agatatgctc
    60421 gcaaaatgag atatgaatgt acgcagaatc cttgttttct acggcattcg cttttttttc
    60481 attggactag ttatatattt ctagggttgt tttcatgtct gagtgcccga tatgatttat
    60541 ttttcgtttc tataattact ttttgccttc cagtttcttt taagattgta ctcaagcaag
    60601 tgggaattgg ttcttttgtc atccatgtat gcaaaatgtt ataatgctgg taaacaaaaa
    60661 tgattacctg tcatttttat ttagttcgta tttaattaag ttgactgtct gtatactctg
    60721 tctaaaactt aagaattgtt gttttcgctg tcgctatcca aatttaatga atgtctgtat
    60781 gttaaaactg ttgtccttgt catagatagt aaaggagagc ttgaaaatga aaactgcgat
    60841 tacgtttcta ttagaggaat atgccgattg ggaaggtgct tatattacta gcacactaaa
    60901 ccaaaaagag ggatggcaaa acaaaactgc ttctatccaa tcagaggtca cttccattgg
    60961 aggattaaaa acaaaaatcg attacttaat cgaacaaata cctgaaaaag ttgacctttt
    61021 tattatgatc ggtggcaatt catgggacat aaaaaatcat catttatatc aaataatcga
    61081 taaattgtta aaaacagacg taccagtagc tgctatttgt ggggcagttg attatttagc
    61141 tcagagcgga ttattgcaag gttacaaaca caccggaaat gcgcaatttc cttggttaga
    61201 atcggaaaat tatcagaata aagaagattt tatagaacaa caagctgtga aagatcgtaa
    61261 tttgattact gcgaatggaa cagctcctat agaattcaca gacttgattc ttcaagcagt
    61321 ccattttgaa acagaagaaa taagagaaaa aaagattcgt ctatacaaac ttggattcta
    61381 tgattactat aaaaagtacg gagatccttt ctcctaatca ttctcttcaa ttaaatactc
    61441 cttatcaata gtatgacaag taattttact gatggttatt tgtcacactt tttctgacat
    61501 ttatcaaaga agatacactc tatttatatt catagatgga atggcaacag tttttttgac
    61561 aaattttata aggtgcagaa cttctttccg tatgctattc cgattgtcct tgacaatgag
    61621 cctcctcgga tgtgacgatc ttcggcagga gctaacagtt aaagttagac tgcctcgcta
    61681 gcgttagcac atccgagctc attatcaagg attcgctgcg ccaatctct
//
LOCUS       DAZKKZ010000007        59156 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.007, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000007 DAZKKZ010000000
VERSION     DAZKKZ010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 59156)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 59156)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..59156
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.007"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            10..642
                     /locus_tag="ACG8LA_000492"
     CDS             10..642
                     /locus_tag="ACG8LA_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202822.1"
                     /translation="MEIQRRTTNFLHLGSFFATLTILFFLCYSYLKTSHAPSSALGWL
                     LLDHSDITEAEENPFFLILSSLCGLLFSVYFGAYFFHRHPGTLNEASSVLIAFKTFSF
                     LAILFYSFNHNTLFFFIMNGLVVILSIFTYFIFSLIFSQLKCPLFFRLVPVTCFIYSL
                     FSFFVLALMPLTNPSTIQVAGNLLDMLFIVSLGVFMWQRKNKQNKKHFEA"
     gene            complement(776..901)
                     /locus_tag="ACG8LA_000493"
     CDS             complement(776..901)
                     /locus_tag="ACG8LA_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family protein"
                     /protein_id="HFQ0202823.1"
                     /translation="MQKNGEKCGMTKEVVIRKVRFLNNQYYDSVKYGILWEELAD"
     gene            complement(1035..1928)
                     /locus_tag="ACG8LA_000494"
     CDS             complement(1035..1928)
                     /locus_tag="ACG8LA_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HFQ0202824.1"
                     /translation="MNYYSKNKENFYQKLTDDPLFSSLTDYLYEHREQETILRELKKE
                     FSQNKFSHFLDLLIDAGLIKREERRYHLNFPIFDPKDYLQQATSAAETIAEQLKRLSV
                     DEQKLAMGEVIWAYCFEDERKEAYFYGVRNSRETELLRTTAGNEKYRFITLSSIEHFP
                     LTLANYFFVQKNQLPVTKAFKELAELIGDVNESYFFDQIEVIVDRIRKNKYKNRRPSI
                     FHQSLLVTNTIKEEESFTLELPIVEKNNFEIELPTLDPSLTMEEIAFLKRQIFSELSK
                     KFIPHAFSYIKEYGTVLVSKT"
     gene            complement(2110..3036)
                     /locus_tag="ACG8LA_000495"
     CDS             complement(2110..3036)
                     /locus_tag="ACG8LA_000495"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004427 - inorganic diphosphate
                     phosphatase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HFQ0202825.1"
                     /translation="MSKILVFGHQNPDTDAIGAAIAFSHLQNELGKETEAVALGTPNE
                     ETQYALDHFQLSAPRVVESAKAENADVMLVDHNEFQQSISDISEVNILAVVDHHRIAN
                     FETANPLYYRAEPVGCTSTIILKLYKENQVTIPKEIAGIMLSAIISDTLLFKSPTCTP
                     EDEAAAKELAAIAEVDLNTYGLEMLKAGTNLSDKSAAVLLDLDAKSFPMGSSNVRIAQ
                     VNTVDLNEVMDRQAELEAAMEDEMKANGYDLFVLVVTNILDSDSELLVAGKGKEKVEE
                     AFQTTLTNNRALLKGVVSRKKQVVPQLTAVFS"
     gene            complement(3121..3882)
                     /gene="pflA"
                     /locus_tag="ACG8LA_000496"
     CDS             complement(3121..3882)
                     /gene="pflA"
                     /locus_tag="ACG8LA_000496"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043365 -
                     [formate-C-acetyltransferase]-activating enzyme activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate-lyase-activating protein"
                     /protein_id="HFQ0202826.1"
                     /translation="MEEKTIGYVHSIETFGSVDGPGLRFVVFMQGCRMRCQFCHNPDT
                     WNIGGGKEYTADELLDKAERFRPYWGDKGGITVSGGEPLLQIDFLIELFKKAKERKMH
                     TTLDTCGKPFTYEEPFFSRFQELMKYTDLLLFDIKHIDNEEHKKLTHWDNENILEMAQ
                     YLSKINKPVWIRHVLVPERSDYDEYLIRLDNFIQTLSNVDRVEILPYHTMGKYKWETL
                     GLKYPLEGIEPPTKERVENAKRLLHTEEYTKYLTR"
     gene            complement(4126..6357)
                     /gene="pflB"
                     /locus_tag="ACG8LA_000497"
     CDS             complement(4126..6357)
                     /gene="pflB"
                     /locus_tag="ACG8LA_000497"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008861 - formate C-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HFQ0202827.1"
                     /translation="MEQWNGFKGTKWKEGVDTRDFIQNNYTEYRGDDSFLEGPTEATE
                     KLWDELQKLNDIQFERNGVYDMDTEIVSTITSHDAGYLDKDLEKIVGLQTDKPLKQAF
                     MPFGGINMANNALKSNGYTPNDELTHIFTDWRKTHNQGVFDAYTAEMRAARKNKIITG
                     LPDAYGRGRIIGDYRRVALYGIDYLMEQKKKDHDMTGYHTMSEEVIRLREEITEQYRA
                     LAQMKEMAAKYGYDISKPAANAKEAVQWLYFGYLAAIKSQNGAAMSIGRISAFLDIYI
                     QRDLDNGVITEKEAQELIDHLVMKLRMVKFARTPEYNQLFSGFPIWATLSIAGMGLDG
                     RSLVTKNDFRLLHTLTNMGPSPEPNLTVLYSEHLPEGFRTYASRIAIESSSIQFENDN
                     QLREQWGSDDCAIACCVSGTVVGKDMQFFGARANLAKTLLYAINGGVDEVTGAQVGPE
                     YRPITSEILDFEEVKHNFMNMMDWLAELYVNTLNIIHYMHDKYSYEAAQLALMDSDLQ
                     RTFATGIAGISHAADSLSAIKYAKVKAIRNEKGIAVDFEVDGDFPKYGNDDDRADELV
                     SWILEYFMGQIKRHKTYRNSKPTTSLLTITSNVVYGKNTGNTPDGREAGKPLAPGANP
                     SYNAEQSGLLASLNSTAKMNYGCALDGISNTQTINPSGLGKEQDTRIENLRNVLDGYF
                     SKGAYHLNVNVFSNDLLRDAMENPMKYPNLTIRVSGYAVKFRDLTREQQLDVLMRTSH
                     DRM"
     gene            complement(6634..9084)
                     /gene="parC"
                     /locus_tag="ACG8LA_000498"
     CDS             complement(6634..9084)
                     /gene="parC"
                     /locus_tag="ACG8LA_000498"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HFQ0202828.1"
                     /translation="MENRQEVQELTLEEVMGDRFGRYSKYIIQERALPDIRDGLKPVQ
                     RRILFAMNKDGNTYDKGFRKSAKSVGNIMGNYHPHGDISIYEAMVRMSQDWKLREVLI
                     EMHGNNGSMDGDPPAAMRYTEARLSKLSGEMLADIEKETVDLVWNFDDTEKEPTVLPA
                     RYPNLLVNGSTGISAGYATEIPTHNLAEVIDGTIYMIDHPQASLEKLMEYIPGPDFPT
                     GGILQGKDEIKKAYETGRGKVILRSKTKIEAMKGNKQQIVITEIPYEVNKATLVKKMD
                     EIRLNKKIDGIAEVRDESDRTGLQIVVELKKDANAQGILNYLFKNTELQINYNFNMVA
                     IDHMTPHQVGLKDILRSYIEHRKQVITKRSQFDLAKAQKRQHIVEGLMKALSILDEVI
                     ATIRESKDKKDAKKNLVDVFQFTEEQAEAIVTLQLYRLTNTDITELQKESESLIAQIT
                     ELNKILSNDKELFSVMKKELREVKKNYSSARLTTIEDEIEEIKIDTQVLVAQEDVIVS
                     VTREGYVKRTSLRSYSASKPEEIGMREGDYLLYSGELSTLDHVLLITNKANVIYRPVH
                     ELPDLKWKDAGEHISQTISNLSVDESILAVFPYQKIQAEKTFVFISKNGLIKQTRMTE
                     FEPWRTYKSRPLSCMKLKAEEDELIAVYLKEDQPGLDVFLVTHQGMGLRYPLTDVPVV
                     GAKAAGVKSMNLKDGDRIINGLLVLAEGDTPIVIVTQRGAVKRMLAQEISQTSRAKRG
                     VTVMRELKKNPHRIIYMSEGRSKEITLMNQKGQQLTIDPTDFPIGDRTSNGSFAMDEK
                     KGGEVIEVIDAPEIFIES"
     gene            complement(9096..11141)
                     /gene="parE"
                     /locus_tag="ACG8LA_000499"
     CDS             complement(9096..11141)
                     /gene="parE"
                     /locus_tag="ACG8LA_000499"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HFQ0202829.1"
                     /translation="MAKKVNNEYNDSSIQVLEGLEAVRKRPGMYIGSTDSRGLHHLVY
                     EIVDNAVDEALSGYGSEIDVTIHEDNSITVADSGRGMPVGMHASGIPTVEVIFTVLHA
                     GGKFGQGGYKTSGGLHGVGASVVNALSKWLIVTIVRDGVEYQQKFKNGGKPDGTLKKI
                     GKTKKANGTTVHFLPDDTIFSTTKFSYEILAERLRESAFLLKGVKISLSDLRGEEPVK
                     EIFHYEEGIKEFVDYLNEEKDTLTPVVYFSGEKEGIEVEVAYQYNDGYSENVLSFVNN
                     VRTKDGGTHEAGMKAAMTKSYNEYARKVGLLKERDKNLEGSDFREGLAAVLSIRVPEN
                     LLQFEGQTKEKLGTPVARTVVDNVISEQMGFYLQENSEMSQMLVRKAIKAREAREAAR
                     KAREESRNGKKRKKGESLLSGKLTPAQSRNPKKNELYLVEGDSAGGSAKQGRDRKFQA
                     ILPLRGKVINTEKAKMQDILKNEEINTMIYTIGAGVGPEFSIEDCNYDKVIIMTDADT
                     DGAHIQVLLLTFFYRYMKPLIEAGKVYIALPPLYKVSKGQGKKQVIEYAWTDDELAAM
                     IKKVGKGYMLQRYKGLGEMNAEQLWETTMDPTSRTLIRVRIDDAAQAERRVTTLMGDK
                     VEPRRKWIENHVQFTLEEDGSILDKKEDTEISPSVSNDLLDEERADKNENNQLFEVE"
     gene            complement(11307..11741)
                     /locus_tag="ACG8LA_000500"
     CDS             complement(11307..11741)
                     /locus_tag="ACG8LA_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0120225 - coenzyme A binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HFQ0202830.1"
                     /translation="MSVKNPTQETIFNYLEEAKNIAVVGLSNKPERTSYMVAQVLQDN
                     GYKIIPVNPLLAGEEILGEKVYANLTEIDDPIDIVDVFRRSEFLPEIAGDFLKTDAKV
                     FWAQLGIENKEAAEMLRKAGRTDIVMDRCIKIELGKLKENQK"
     gene            11868..12506
                     /gene="plsY"
                     /locus_tag="ACG8LA_000501"
     CDS             11868..12506
                     /gene="plsY"
                     /locus_tag="ACG8LA_000501"
                     /EC_number="2.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008374 - O-acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006654 - phosphatidic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HFQ0202831.1"
                     /translation="MKLILLLILAYLLGSIPSGVWIGKLFFKKDIRQHGSGNTGTTNT
                     FRVLGKTAGIVVLLMDILKGTLATCLPMIFHLSGINPLWFGVCAILGHTFPIFAGFKG
                     GKAVATSAGMLLGFNPVFFVYSCIIFIVSLFCTSMVSLSSMISAVLITLSTIVLPYVA
                     PVILAKPNWLLTIIAFLVSSFIFYRHKDNIKRIRNHTESRIPFGLNSSKKKS"
     gene            complement(12638..13513)
                     /locus_tag="ACG8LA_000502"
     CDS             complement(12638..13513)
                     /locus_tag="ACG8LA_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HFQ0202832.1"
                     /translation="MTVIIQNDQLIAEIAEHGAELISLKSKEHGLEYIWQGDPAYWGR
                     HAPVLFPFVGRLKDDQYVYQGKTYQMGQHGFARDMDFEVIEHGQEMASFILRSTPETL
                     EKYPFDFELVISYELGGDGITVHYQVANTGEKEMFFSIGGHPAFNVPLEEGLSFEDFY
                     LAFSPLKSRLRLPLKGPFIDMDQKTLGQTNTNLALNRELFEQDALVFETRGLNAYAIR
                     SEKSSHSVTLSYKDMPYVGIWSPYPKEAPFVCIEPWCGIADTVNSSGNLMEKVGINQL
                     GAHEIFKTKYSITVK"
     gene            complement(13595..14386)
                     /gene="codY"
                     /locus_tag="ACG8LA_000503"
     CDS             complement(13595..14386)
                     /gene="codY"
                     /locus_tag="ACG8LA_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HFQ0202833.1"
                     /translation="MTDLLTKTRKINTLLQQKNTFDMQADLPYDKMAVTLGGILDSNT
                     YIIGSDGVLLGYNERHDVNNERIKTMFVEKQFPESYTDTVAQLMKTEANIPITSDITA
                     FPVESREKYPFGLTTVVPIFGAGERLGTIILSRMEQSFADDDLVLAEYGATVVGMQIL
                     YQKSRSIEADVRSATAVQMAINTLSYSELKAVQAIFEALDGDEGRLTASNIADSIGIT
                     RSVIVNALRKLESAGIIESRSLGMKGTYLKVLNSRFKDELAKHSY"
     gene            complement(14404..15804)
                     /gene="hslU"
                     /locus_tag="ACG8LA_000504"
     CDS             complement(14404..15804)
                     /gene="hslU"
                     /locus_tag="ACG8LA_000504"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002409948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009376 - HslUV protease complex
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease ATPase subunit HslU"
                     /protein_id="HFQ0202834.1"
                     /translation="MYELKQTPRQIVSELDEYIVGQHAAKKSVAVALRNRYRRLQLDE
                     KMQQDITPKNMLMIGPTGVGKTEIARRLAKIVNAPFVKVEATKFTEVGYVGRDVESMV
                     RDLVENAIQIVEKEQYSRVYTSAKKNAEKRLVKILVPGIKKEQKQSTNQFEQMMNLFN
                     ASQQNTAEPQEEVTEDIRINRRTVLEQLQKGLLDSREVTIEVEDQKKPAPMMNNGLEQ
                     MGIDLNETLGALTPKKKVERTVTVKEALELLIKEESAKLVKDADIHSEAIKLAEESGI
                     IFIDEIDKITSKSQQSGEVSREGVQRDILPIVEGSQVNTKYGIIQTDHVLFIASGAFH
                     LSKPSDLIPELQGRFPIRVELDDLTAEDFVKILTEPNNALVKQYVALIGTENVSVTFT
                     KEAIERIAQIAFDVNRDTDNIGARRLHTILEKLLEDLLFEAPDMQMGEITITEAYVDD
                     KLGSIAANEDLSRYIL"
     gene            complement(15818..16366)
                     /gene="hslV"
                     /locus_tag="ACG8LA_000505"
     CDS             complement(15818..16366)
                     /gene="hslV"
                     /locus_tag="ACG8LA_000505"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009376 - HslUV protease complex
                     [Evidence IEA];
                     GO_function: GO:0004298 - threonine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HslVU peptidase proteolytic subunit"
                     /protein_id="HFQ0202835.1"
                     /translation="MVESPFHSTTICAVEKDGKFAMAGDGQVTMGESVVMKGTAKKVR
                     RIYNGEVVVGFAGSVADAFTLEEKFEGKLNEYNGNLQRAAVELAQEWRTQQSMQKLEA
                     MLIVMNDKEMLLVSGTGEVITPDDGILAIGSGGNFALAAARAMKNYAQNDMSAKEIAE
                     NALNIAADICIFTNHNIIVEEL"
     gene            complement(16403..17308)
                     /gene="xerC"
                     /locus_tag="ACG8LA_000506"
     CDS             complement(16403..17308)
                     /gene="xerC"
                     /locus_tag="ACG8LA_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerC"
                     /protein_id="HFQ0202836.1"
                     /translation="MTEATWEQKFLRYLIVERGYSEKTKEAYEEDILHFKHFLEESGD
                     ADLLKAEYFTVRVYLSALADHRPSYSRNSISRKIASLRSFYQYLLKEEVIKENPFSYV
                     HLKKKNLRLPRFFYENEMQALFDSVAGDSPLDLRNRALLEVLYGSGIRLSECSSLSVS
                     DIDFDSEVMLIHGKGNKERYAPLGSFAQDALQEYFREGRQVLMTKYHEEHDIVFVNHH
                     GKPITPTGIEYVLNQMIKKSSLDSDIHPHMLRHTFATHLLNNGADLRTVQELLGHANL
                     STTQIYAHVTKESLQKNYRSFHPRA"
     gene            complement(17506..18882)
                     /gene="trmFO"
                     /locus_tag="ACG8LA_000507"
     CDS             complement(17506..18882)
                     /gene="trmFO"
                     /locus_tag="ACG8LA_000507"
                     /EC_number="2.1.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0047151 - tRNA
                     (uracil(54)-C5)-methyltransferase activity,
                     5,10-methylenetetrahydrofolate-dependent [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FADH(2)-oxidizing
                     methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))-
                     methyltransferase TrmFO"
                     /protein_id="HFQ0202837.1"
                     /translation="MEITKKTSKNNRKEVLSLKMVNVVGAGLAGSEAAWQIAQAGVPV
                     RLYEMRPVKSTEAHHTSNFAELVCSNSLRGNSLANAVGLLKEEMRRLNSVVITSADET
                     AVPAGGALAVDRDSFSETITRKVKEHPLVTVINEEITEIPEGITVVATGPLTSHPLAE
                     SIKAFNGSDGFYFYDAAAPIVDKATIDMDKVYLKSRYDKGEAAYLNCPMTEEEFKAFH
                     EALINAEVAELKSFEKEKYFEGCMPIEVMAQRGFKTMLFGPMKPVGLEDPKTGKRPYA
                     VIQLRQDNAAASLYNIVGFQTHLKWGEQKRVFRMIPGLENAEFVRYGVMHRNSFMNSP
                     ELLKPTYQSTKREDLFFAGQMTGVEGYVESAASGLLAGINAARLAKEMEPVEFPQETA
                     IGSMAYYITHAEGKHFQPMNANYGLFPELPERIRDKKARYEAIAQRALKANEAIKTEL
                     EKTAIPNE"
     gene            complement(18851..20929)
                     /gene="topA"
                     /locus_tag="ACG8LA_000508"
     CDS             complement(18851..20929)
                     /gene="topA"
                     /locus_tag="ACG8LA_000508"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002380330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HFQ0202838.1"
                     /translation="MAYKYLVIVESPAKAKTIEKYLGRNYKVMASVGHIRDLPKSKMG
                     IDFENNYEPHYISIRGKGDVIKSLKAAAKKAQKVYLASDPDREGEAIAWHLAYLLGLD
                     LKEKNRVVFNEITKDAVKAAFKEPRTIDVDLVDAQQARRTLDRIVGYSISPILWRKVK
                     KGLSAGRVQSVALKIIIDREKEIREFVPEEYWSIDGNFKKARKKFKANFWGIDGKKKK
                     LPDAQSVKEVTARIDGTDFEVKKVEKKERKRNPANPFTTSSLQQEAARKLNFRTRKTM
                     MVAQQLYEGITLGKQGTVGLITYMRTDSTRIADTAKAEAAAFIEDTYGKEFSRHDHRK
                     IKNAQGAQDAHEAVRPTSVLRTPDELKQYLDKDQLKLYTLIWSRFVASQMTPAILDTM
                     KVTLEQNGVIFIANGSKIKFKGFMQVYVEGRDDGKEEKENILPELEEGDVVQSVDIEP
                     KQHFTQPPARFSEATLIRALEENGVGRPSTYAPTLDTIQRRYYVKLTQKRFEPTELGE
                     IVNSLICEFFPQIVDIHFTAEMEGDLDKIEEGTEAWVKVVDRFYKPFEKELTNAEEKI
                     EKIQIKDEPAGFDCDVCGHPMVIKLGKYGKFYACSNFPDCRNTKPIVKEIGVTCPVCH
                     EGQVIERKSKKNRLFYGCSRFPECEFTSWDKPVGRNCPKCDGYLVEKKVKGGKQVVCV
                     NGDYEEDIQK"
     gene            complement(21051..21908)
                     /gene="dprA"
                     /locus_tag="ACG8LA_000509"
     CDS             complement(21051..21908)
                     /gene="dprA"
                     /locus_tag="ACG8LA_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009294 - DNA-mediated transformation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-processing protein DprA"
                     /protein_id="HFQ0202839.1"
                     /translation="MYQIEENLLKLAYTKGISSQGKWALANWMMQYPYKEIGFEDIIK
                     IGKITKHRELFRKSWQEIHANWGKIQSKQSFITCFDPKYPPQLLHLTYPPIVLFYNGD
                     LSLLSCNMLSVVGGRHTSALAKKTVYYLLKPVIEAGYVIVSGCAKGIDTYGHQAAISH
                     GGRTIAVIGTGIEQVYPAENRDLQEVIANDHLLLSEYPPQSGPKKHCFPMRNRIIAAL
                     SKGTCVFEAKKKSGSLITAQQALDLGRTVFSVPGNILTEHSTGCHHLIQDGAVCTVSG
                     EDILAEFKE"
     gene            complement(21964..22731)
                     /locus_tag="ACG8LA_000510"
     CDS             complement(21964..22731)
                     /locus_tag="ACG8LA_000510"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HFQ0202840.1"
                     /translation="MTESIQSIKERLKSIQRIDDPTLESLRNDPRKGVQQALASFERR
                     LKKEALIKEKYEEMFCFEKQGYAQGHQWIAGIDEVGRGPLAGPVVAAAVILPKNEIIL
                     GLNDSKQLSEKKRELLYQQVQEKALAIGIGIVDQQTIDDVNIYEASKLAMIQAVEKLS
                     IVPSYLLIDAMTLDLPIQQEKIIKGDARSVSIAAASIIAKVYRDQLMKEYDVLYPGYG
                     FSHNAGYGTKEHLEGLERQGITPIHRKSFAPVKKYLQ"
     gene            complement(22724..23584)
                     /gene="ylqF"
                     /locus_tag="ACG8LA_000511"
     CDS             complement(22724..23584)
                     /gene="ylqF"
                     /locus_tag="ACG8LA_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HFQ0202841.1"
                     /translation="MTIQWFPGHMAKARREVSEKMKYVDIVFELVDARLPLSSRNPML
                     DQIIQQKPRLVLLNKADLADPQQTKLWQEYFRKQGHLALAITAQESKGIKGLVPAAKE
                     ALKEKRARDAARGIKPRAIRAMVLGIPNVGKSTLMNRLVGKKIAQTGNKPGVTKGQQW
                     LRLGNELELLDTPGILWPKFEDEEIGKKLALTGAIKDQLVHLDDLAIYGLDFFARYYS
                     GRISDRYGLSIEQEEKLAPELLMDITAKRGYKEDYDRGSELVVHDIRQGKLGRYTLDR
                     CEEMEQKSDD"
     gene            23844..24242
                     /locus_tag="ACG8LA_000512"
     CDS             23844..24242
                     /locus_tag="ACG8LA_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFQ0202842.1"
                     /translation="MNSMVFVNFPVADVNRSVAFYEKLGFKKNEEFSTEEAGSMVWDD
                     TFWIMLLSHDFYKKFIKDKEIADNKKTSGALISFSVENADEVKKFAQIAKENGGTFHE
                     VDMGMPEEEMFSLEVQDLDGNTLEPVWMKM"
     gene            24479..25021
                     /locus_tag="ACG8LA_000513"
     CDS             24479..25021
                     /locus_tag="ACG8LA_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HFQ0202843.1"
                     /translation="MNTLIAKDVFRLPEMNARLLSTSALLLALDVILYKIAIGPAYFQ
                     ITFGFLSMALMGYLYGPIWAGLLEMLSNTLNFTIFGSGTFQAAFLITAFLGGFINGLF
                     LYHKKINLPSVIAAQLLIMIPVSLFINSWLMSVLFGADFKVIFLGRFIRNMIQIPIQI
                     MVVYSFIKTLEARKVFKRAV"
     gene            complement(25104..25655)
                     /gene="lepB"
                     /locus_tag="ACG8LA_000514"
     CDS             complement(25104..25655)
                     /gene="lepB"
                     /locus_tag="ACG8LA_000514"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HFQ0202844.1"
                     /translation="MTKKQRYINRFWLVFKYLLVSVFLAFMLRGFLFIPVPVEGNSME
                     NVLKQGDMVVMEKFSEIRRFDIVVFQLADGTIYIKRVIGLPGENVSYQNDQLKINGKV
                     VKEPYLTKNLKSDHANASYTTDFTLQELTGQSKLPEDNYFVLGDNRRVSKDSRSFGTI
                     NKTDILGKARFVYYPLDEIKWIQ"
     gene            complement(25807..26034)
                     /locus_tag="ACG8LA_000515"
     CDS             complement(25807..26034)
                     /locus_tag="ACG8LA_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HFQ0202845.1"
                     /translation="MNRSFFHYLMTLRGGGTHDALSVFATEAGKDIQFPKHSSSYEEI
                     SNYLELNVDYLPSMDIFDEAWEKYLENNHDI"
     gene            complement(26031..26549)
                     /gene="msrA"
                     /locus_tag="ACG8LA_000516"
     CDS             complement(26031..26549)
                     /gene="msrA"
                     /locus_tag="ACG8LA_000516"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008113 - peptide-methionine (S)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_function: GO:0033744 -
                     L-methionine:thioredoxin-disulfide S-oxidoreductase
                     activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HFQ0202846.1"
                     /translation="MERAIFAGGCFWCMIQPFDTLPGIHTVMSGYTGGHVPDPTYEQV
                     KSQTTGHTEAVEIIYDPTLISYEQLVELYWQQTDPTDAFGQFEDRGDNYRPVIFYLTE
                     EQRIIAEKSKKQLAESGRFEQPIVTKIEPAQPFYLAEEDHQEYYKKHPENFKRNHARR
                     AAFIEENWRNEG"
     gene            complement(26569..27282)
                     /locus_tag="ACG8LA_000517"
     CDS             complement(26569..27282)
                     /locus_tag="ACG8LA_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HFQ0202847.1"
                     /translation="MKTRSDVSSNKTKKTNYWKFAFLILLGVVLGSTVFLGSRIFANR
                     EPELPEIPALTERQGDPVLTINSNKEKVNQIISFFLSEYQKDSDIEYKFYLENEALLN
                     GTFEVLGFPIDFYLYFDPYVMENGNVQLKARSLSIGTLSLPIKDVMNMIKRNYKLPDW
                     IEVNTDDLTIMLRLDQFRMQNGMYIKADKIDLVNDDIRFSLYLPKDTSDASNNSNTNK
                     TSTSSTESKTKENKKSSDE"
     gene            complement(27285..28181)
                     /locus_tag="ACG8LA_000518"
     CDS             complement(27285..28181)
                     /locus_tag="ACG8LA_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HFQ0202848.1"
                     /translation="MKLTKRHLILVLFPLLIAIIIYAGLAASIPKAGPLMKPVTTVRE
                     DPNKKEKLHYIAIGDSLTEGVGDQTKQGGFVPLVANDLKDRYNLTAVETENYGVNGER
                     SDQILKRVKTKEEIRNNIKTADFITLTVGGNDLMKVIQNNLFGLTVNSFKKPLKNYQE
                     NVTELLEEFRSLNKTAPIYILGIYNPFYLNFPEITDMQTIVNNWNKGTETVTKKMPNC
                     YFIPINDLLYQGLNQEVGVTEEGTDQTTSTTENLNGIKNNVLYEEDHFHPNNLGYQLM
                     ANAVRDQLIETQNQWLEKEDDQ"
     gene            complement(28339..29181)
                     /locus_tag="ACG8LA_000519"
     CDS             complement(28339..29181)
                     /locus_tag="ACG8LA_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005504 - fatty acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HFQ0202849.1"
                     /translation="MTNVKIVTDSSCTMEKNVRDALGIRVMPLSIMIDGTVYPDDDQL
                     DGERFMEMMAKAKNLPKTSQPPIGEFISMYDELGEDGSEVISIHMTKGLSGTVEAARQ
                     ASNLTKTKVTVIDSDTTDQGLSFQVIRAAELAKEGKTVEKILEEVKKVQDNTKLYIGI
                     STLDNLVKGGRISRTTGLLSSVLNIRVVMNFAHSELIPVTKGRGKKTFDKWFNNLKNE
                     LKELPNVRQIGISHADAKELAQEFKEGLQELFPDMHIPVLHTNPVIATHTGKDAFAIM
                     YYVD"
     gene            29313..29966
                     /locus_tag="ACG8LA_000520"
     CDS             29313..29966
                     /locus_tag="ACG8LA_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HFQ0202850.1"
                     /translation="MEKTKFNRTYEILNEVFNAVTHGIGTGLSIAGLVVLLVKGAHLH
                     SSLHIVSYAIYGSMMILLFLTSTLFHSLIFTKAKKVFQVFDHSSIFLLIAGSYTPFCL
                     LSIRGWLGWTLFVLIWLFAILGIIYKALTLHKRERVSKVSTIIYIFMGWLCVVAAVPL
                     YHSLGMTGVILMVAGGLSYTIGAFFYSLNSIRYMHVVWHLFVMLGAGFMYFSVLFFT"
     gene            complement(30029..30556)
                     /locus_tag="ACG8LA_000521"
     CDS             complement(30029..30556)
                     /locus_tag="ACG8LA_000521"
                     /EC_number="1.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004146 - dihydrofolate reductase activity
                     [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HFQ0202851.1"
                     /translation="MLAAIWAQDENGLIGKEDRLPWRLPNDLKFFKQMTEANTLVMGR
                     KTFEGMGSRPLPNRQTIVLTRDSSYKAEGVHVMHSVEDVLALEKETDGIFFIAGGSAV
                     YQEFLPFCTILYRTVIHHVFDGDAYFPPVDWSDWSLINTSQGEMDEKNRYPHQFETYQ
                     RNENPVKSGTGELTI"
     gene            complement(30576..31523)
                     /locus_tag="ACG8LA_000522"
     CDS             complement(30576..31523)
                     /locus_tag="ACG8LA_000522"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004799 - thymidylate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006231 - dTMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HFQ0202852.1"
                     /translation="MEQAYLDLGRKLLEEGHRKEDRTGTGTLSLFGYQMRFDLQKGFP
                     LLTTKRVPFGLIKSELLWFLKGDTNIRYLLQNKNHIWDEWAFERYIKSPDYNGPDMTD
                     FGHRCLTDPEFNEEYKKQSKLFCEKILTDDSFAETYGDLGHIYGYQWRHWETKDGGFI
                     DQIKQVIEAIKKTPDSRRLIVSAWNPEDVPSMALPPCHTMFQFYVQEGRLSCQLYQRS
                     GDVFLGVPFNIASYALLTHLIAHETGLAVGEFVHTLGDAHLYINHIEQMKEQLSREIR
                     AFPTLVLNQEKQSVFDFEMEDIQLEGYDPHPAIKAPIAV"
     gene            complement(31535..33418)
                     /locus_tag="ACG8LA_000523"
     CDS             complement(31535..33418)
                     /locus_tag="ACG8LA_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HFQ0202853.1"
                     /translation="MKELKVTDLKKTYGEKDLFDQISFLVHEKDRIGLIGTNGTGKTS
                     LLNIIAGIDSSDGDRQTVFYPTDYRIGYLSQAAEFSDELTVLQAVFQGNSPLIQTVRA
                     YEEALIELGENGEDPDVQKRYAKAEEQMNKEDAWTTDTNAKIILQKLGISELDKKIST
                     LSGGQKKRVSLAQVLIDEPDLLLLDEPTNHLDYEAIEWLENYLKQYRGALLMVTHDRY
                     FLDRVANRIFELSFGKLYEYKGNYEAYVLEKAERDRVEVEQEEKRKRLYKQELAWMRA
                     GVQARGTKQQARINRFEDLKENLYQVNQEDDLELNLATQRLGKKVLEIKDGSYRINDQ
                     TLLEHLDLLIQSRERLGITGKNGAGKSTLLNILAGRIPLDSGTMSIGETVHLAYYTQE
                     NEEMAPDKRMIAYLQEAAEEAKTADGSQIGVAELLERFLFPRFMHGTLIGKLSGGEKR
                     RLFLLKLLIQQPNVLLLDEPTNDLDIATLTILEDYFRSFPGAVITVSHDRYFLDKVAD
                     KLLVFQGNGKQELYYGNMSSYLLKQKETQQPAEKAKPKIQSKEPAEKKKLSYMEQKEW
                     ETIEDEIAELEEKISLLQEEMNHQGDNFTRLQELQNDVSETEAQLEEKMARWEYLSEW
                     VED"
     gene            complement(33581..35659)
                     /locus_tag="ACG8LA_000524"
     CDS             complement(33581..35659)
                     /locus_tag="ACG8LA_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HFQ0202854.1"
                     /translation="MEFAELVIVFAVTITLSNIASRILPMIPAPLIQIFLGVVLGLTE
                     WGQSIDFEPELFLVMIIAPLLFREGEKADISSILKNFGTILFLAFGGVILTLVGVGAT
                     LSFLLPSVPLAACFAFGAALGPTDAVAVSSLSGRVNIPKKAMHILEGEGLLNDASGVT
                     AFQFALGALITGSFSAVNAGMSLVVSSIGGALIGFLLVWFKQKIIHLIEKASAQDVTG
                     YLLIELLLPFLAYVLAEAFDVSGIIAAVAAGILQASGFRKISVFDAELSSLSHSTWTT
                     IAFTLNALVFIFLGIELTQVFSPVWGDGLYPNGLLLAIIVLISVMLFVIRFISISLFY
                     VFKDGSKKFKKQLNEILILTFGGVKGTVSLATIFILPFSINNMMFYQRSLLLFLTAGV
                     ILVTLVIGIIVLPMLTETEEAKSTDLNALMILEEVVEVLRKEIKEIDRNTKEFLATEA
                     VIENYQERIRDLYLEDLTDDEKQEVQEIQALILSIERDGLDESYRSGKLSSNGYRFYS
                     RFLSRFEHSITSQILSFIGFWFIVVRRLMRIVLHPKMFWQRRYADRQTFISDEDIQEI
                     RETYQKNTQLIIESLDNLTDIYDETMVQFFIQQRKLEGIKMNSGNLISSWMIQQDSLF
                     TKKMLRGYYLERKIIDEYEVAEKITTFSANSYRRNINLLESYTMNKPSDNFSFRFAFR
                     AKSKKTSPIK"
     gene            complement(35672..35947)
                     /locus_tag="ACG8LA_000525"
     CDS             complement(35672..35947)
                     /locus_tag="ACG8LA_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202855.1"
                     /translation="MRESFEQQKKLLHDRYGALSMDDRRQILCKLRKRNILMYRQLER
                     LKHDLLRLESKRVQCELEGNQTQVEVVETKILKKKEQFLKMLTQNKK"
     gene            complement(36309..36764)
                     /locus_tag="ACG8LA_000526"
     CDS             complement(36309..36764)
                     /locus_tag="ACG8LA_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202856.1"
                     /translation="MSKEMTALKFYFRNGETWTINRRHIGDLWIKQITTSFGRINGSE
                     FVEIHPCAGFKIEIFHEGDAVATHDINLGGLEMGMFNRALKYEDIERMEILYRNGTPD
                     LVYFPYLDKGTEGLDNQYQSTKISEKTGNLYIVINPDQRVEDVYGEFFE"
     gene            complement(36918..38126)
                     /locus_tag="ACG8LA_000527"
     CDS             complement(36918..38126)
                     /locus_tag="ACG8LA_000527"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0001680 - tRNA 3'-terminal CCA addition
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HFQ0202857.1"
                     /translation="MKLKQLPLEYQKAIPVLKKLENAGYEAYFVGGSVRDILLNQPIH
                     DVDIATSAFPEEIKQLFPKTIDIGIEHGTVLVLENDEQYEITTFRTESTYQDYRRPDH
                     VEFVRSLAEDLKRRDFTINAFALKEDGEIIDLFDGLQDLEEQILRAVGNPHERFHEDA
                     LRMMRGLRFVSQLGFKLEEETFYAIKENHELLGKISVERINVEFIKMLLGNERAAGIH
                     AFIETECYICCPGLKEEGEALLRFAELPSVPLKEESQAWALLISQLDLKENEIRSFLK
                     SWKCSNQMIKDVQALVQGLRQRETGALEPFELYFLGKKHALQVEELMIYFDETPQMDA
                     VGESYDRLPIKSLSELAVDGKILLEETGKKPGKWVSEALQLAEKAVVEQRIKNDKKQV
                     LDFLSKEKLI"
     gene            complement(38238..38570)
                     /locus_tag="ACG8LA_000528"
     CDS             complement(38238..38570)
                     /locus_tag="ACG8LA_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HFQ0202858.1"
                     /translation="MDKKRSLYSMQQEVDEYIQQFKVGYFSPLAQMARLTEEVGELAR
                     EVNHTYGEKSKKASEPVNSVAEELGDVLFVTMIMANSLNIDLTEVFEKNMEKFNQRDH
                     NRFERKDE"
     gene            38718..39593
                     /locus_tag="ACG8LA_000529"
     CDS             38718..39593
                     /locus_tag="ACG8LA_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFQ0202859.1"
                     /translation="MVKRKTVKEVLFIIIGTSIYAFGLVYLNIANHLAEGGVSGITLI
                     LRALFGIDPAYTTLLINIPLILLGGKILGKRSLAYTVLGTLSLSFFLWIWQRVPLEIN
                     LQHDLLIVSLLAGLVAGVGSGIVYRMGGTTGGSDIIARILEQNYGITMGRSLLAFDII
                     VLLASLTYIDLKRMMYTLIVSYVFSRVIDSILDGGYSAKGLLVVSNKSEEIAPLLMTG
                     LQRGVTFLSGEGAFSGNSKKIIYMVVSSSELTEAKRIVHEIDEKAFLSIINVHEVEGQ
                     GFTYLKPQTRLLKKL"
     gene            complement(39675..40256)
                     /locus_tag="ACG8LA_000530"
     CDS             complement(39675..40256)
                     /locus_tag="ACG8LA_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ReoY family proteolytic degradation factor"
                     /protein_id="HFQ0202860.1"
                     /translation="MLIDVREKKNFLTWMVNHVSFSRREVFWILNYLANHEAILSNVH
                     FVEGANFADRGLQISDLSVEGEPMKLFLQGKEFTDTDQIFHEIRLNWKKPLYVECIFE
                     NAWQTREYLSILEDNPFSSWDSSVSEEDTELIERYFQEKEEEAKLKMLYAQIDQALED
                     GDRDAFLKLSDEVNRKILLQTQKKSNRVSEHNN"
     gene            complement(40262..41521)
                     /locus_tag="ACG8LA_000531"
     CDS             complement(40262..41521)
                     /locus_tag="ACG8LA_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HFQ0202861.1"
                     /translation="MNTNSEKMLQALSDEDLSQAQIFLEKALKEDPADILAELGEELL
                     AIGFLIEAKQIFEQLINQYPENDGLNIPLAEIAIEDNEIDLAFEYLEKVDKQSDYYPQ
                     SLLAIADLYQVIGIPEVSEAKLKEAAGLLPDEPLIQFALAELYFSVDRFKEAAVVYET
                     LLASGINEISGISMQERLGQSLSMQGEFEAAIVPLEEALKEERTDDRLFQLAFTNLQL
                     KENQQAINYLEELREVNPHYQSLYLYLGQALQEEEMIEEAQTVLEEGIKENPYQVELY
                     HLASENAFRLHDRQRAEELLLKALEVGDKQDETLLTLSNLYLDDERYEDVIQVINQME
                     ETANPYAEWNLAHAYNELEDFTVAAVHYEQAYHELSHEPDFLKEYAFFLREEGQLKRA
                     QELLTYYLTLEPGDMEALSLLDDLTER"
     gene            complement(41523..42569)
                     /locus_tag="ACG8LA_000532"
     CDS             complement(41523..42569)
                     /locus_tag="ACG8LA_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202862.1"
                     /translation="MELDYQVEDALTKVFYGETLVSQLRELSIDQPILFLTNQRYYDL
                     FADKINPLFANQANNDWYICANTQCNHLTELKNLLDFVKRYPENQSMFIIGFGNEGIM
                     DLAGFFQKHTTLDSSLWMIPVSIRSLSRALTPQRTILQLPNRVVLQTINLPERIVYDQ
                     TISERQVDGKQIDFLTFICCGMICDHRFLQNLYKNYPNKKQLTTRPFAGMIEEMIYFY
                     QLEAENLSNYGKLFEQAFYLTENGHLLSASMKKFLGMMFHFVWNLQAYPFDFQLKNFF
                     VWLDLLGYPIHWLEQISKMEYLEKVLFLAEKSKKILVLEKIGIIDGYQHPNEKELLRT
                     MTVFQQIVSEIRGN"
     gene            complement(42804..43079)
                     /locus_tag="ACG8LA_000533"
     CDS             complement(42804..43079)
                     /locus_tag="ACG8LA_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007208657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HFQ0202863.1"
                     /translation="MANKAELIEKVASATDLTKKDATAAVDAVFSTIQDALANGEKVQ
                     LIGFGNFEVRERAARKGRNPQTGEEIEIPASKVPAFKPGKALKDAVK"
     gene            complement(43322..44632)
                     /gene="der"
                     /locus_tag="ACG8LA_000534"
     CDS             complement(43322..44632)
                     /gene="der"
                     /locus_tag="ACG8LA_000534"
                     /EC_number="3.6.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HFQ0202864.1"
                     /translation="MANPTIAIVGRPNVGKSTIFNRIAGERISIVEDTPGVTRDRIYA
                     KGEWLGREFSVIDTGGIDLGDEPFMDQIKHQAEIAIEEADVIICVVSGREGVTDADEM
                     VAKILYRSNKPVILAVNKVDNPEMRNDIYEFYSLGLGDPYPVSGSHGLGIGDILDEAV
                     KYFSEETEEEDDDTIKFSLIGRPNVGKSSLINAILGEERVIVSDIEGTTRDAIDTHFV
                     SESGQKFLMIDTAGMRKRGKVYENTEKYSVMRAMRAIDRSDIVLMVLNAEEGIREQDK
                     RVAGYAHEAGRGIIIVVNKWDLVKKETNTMRDFEQEIRDEFRYLDYAPIVFVSAVTKQ
                     RLERLPEMIEQVSMNQNLRISSAVLNDIIMDAVAINPTPTDKGKRLKIFYATQVAVKP
                     PTFVVFVNEEELMHFSYERFLENQIRKAFTFEGTSIRIIPRRRK"
     gene            complement(44814..46043)
                     /gene="rpsA"
                     /locus_tag="ACG8LA_000535"
     CDS             complement(44814..46043)
                     /gene="rpsA"
                     /locus_tag="ACG8LA_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HFQ0202865.1"
                     /translation="MTEFDQNQENNQSMEDAMKSVQEVKVGDVVKGEVLVIEDKQVIV
                     GIEGAGVEGVVPAKELSTLPVEDISEVVKVGDVLDLVVISTIGKDKENGSYLLSKRRL
                     DAKKVWEDIERDFQEGKVIEAPVTNVVKGGLVVDVGVRGFVPASMVEDHFVADFSDYK
                     GKTLSFKIIEIEPSENRLILSHKAVVENEREEKKKEILSTIHEGDVLSGRVARLTDFG
                     AFVDLGGIDGLVHVSEISHSHVAKPSDVLAVNDDVNVKVLSINPEQERVSLSIKDTQP
                     GPWSEIDTKAPVGTVLDGTVKRLTSFGAFVEVFPGVEGLVHISQISHKHIATPHEVLH
                     EGDEVKVKVLEIHPEEHRIALSIKALEEKPASEEEPKNVESYELPEENTGFTMGDILG
                     DALKEEVEEKATDDSEK"
     gene            complement(46178..46858)
                     /gene="cmk"
                     /locus_tag="ACG8LA_000536"
     CDS             complement(46178..46858)
                     /gene="cmk"
                     /locus_tag="ACG8LA_000536"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004127 - (d)CMP kinase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HFQ0202866.1"
                     /translation="MTQISIAIDGPASSGKSTVAKILAKELNYIYTDTGAMYRAVTYL
                     AITNNVSFSDEEGLVSLIKKYPISFSQQEDGQHVFIASKDVTLEIRQPDVTKAVSEVS
                     AHGKVREELVAVQRKIGERGGVVMDGRDIGTAVLPNAEVKIFLVASVSERAERRFKEN
                     QEKGIPTDLETLTKEIQERDHYDSTRDVSPLKQAEDAVRIDTTGKSIPEVVAAIKAVV
                     LKKGYLLF"
     gene            complement(46907..47542)
                     /locus_tag="ACG8LA_000537"
     CDS             complement(46907..47542)
                     /locus_tag="ACG8LA_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAG1386/EF1546 family surface-associated
                     protein"
                     /protein_id="HFQ0202867.1"
                     /translation="MSRKDRHQSTENNETQEPWEQPIYDTDDEVSSRSSQRQQKKGNT
                     LFLSLFLILLVLCIAIPAGAYFWIRNGSSNNATAATSSETSTSVVESSTSTTKEESTE
                     TSTVESSTIAEESTVSQDTGVTSESSIAAETTPTSSSEATYQAGDSSSNAAETTPSSS
                     AAAGSTTTVQAGEGPKQVAERAGITTDQLFELNGLDPNNFMLYPGQELRIK"
     gene            complement(47608..49011)
                     /locus_tag="ACG8LA_000538"
     CDS             complement(47608..49011)
                     /locus_tag="ACG8LA_000538"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0043138 - 3'-5' DNA helicase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecQ"
                     /protein_id="HFQ0202868.1"
                     /translation="MLINELKKYFGFDSFRPGQEEIIQALLDGEDTLAILPTGTGKSL
                     CYQLTGYLMEGLVIIVSPLLSLMEDQVTQLQKRGEKRVAAFNSLLSQSERRYVLRHLS
                     QYKFLFLSPEMLTNPSLLEHLKKQNIALYVVDEAHCVSQWGVDFRPEYQQLGKIRKLL
                     GNPVTLALTATATDLVARDIRHVLFDRPPKEIRQSVNRQNISLFVRKTQQKEQELEHF
                     MERAQGAAIIYCATKKEVERLYHLFRERFTVGYYHGGLDAAQRRQLQQQFVKNQLQFL
                     IATNAFGMGIDKSDIRYVVHYDLPDSLENYVQEIGRAGRDQEESAAILFYQSGDERIH
                     YFFNQLSREQRQSFELYLEYATEQAPFDELQKKWMELIQQSEKPENWVERLKRQEKEK
                     EFRLQQMLRYINEENCRRKFILAYFGEKLSEKPQNCCDIDGAKAELLPKRKLFSKTEQ
                     LHWGTILLNLFKKNMEH"
     gene            complement(48998..50029)
                     /locus_tag="ACG8LA_000539"
     CDS             complement(48998..50029)
                     /locus_tag="ACG8LA_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0202869.1"
                     /translation="MIVFILSLFSSGHKLRISSLYQLLVGKRTTSVLIYGFTHELLFI
                     HNSFPELKQDKFYQILQKIAQQGWIEINENEAKLTPAGADMLSEHQIEHTGLRFDRYG
                     RTGETSWRLIKFAVQVISNLATGIQDYLPAETSPFYTFQLKKWLSESQLPREILIDTA
                     YESLVQLFSEIPEEAADFLANQLSGNERTGLLPYQLAKNNDESAVYLQQSRCIHLLLA
                     QIEKRPDSLWHALIDSLLQQNFNQSMMITKQMFMNGQTIDQIMAIRHLKRGTVTDHLI
                     EWALFFDDFPYEWILSAETIERLEPNKDSVREWRFSEWNVDGQLDYGEFRLYQIYLLR
                     KEAIQNVNK"
     gene            50060..50281
                     /locus_tag="ACG8LA_000540"
     CDS             50060..50281
                     /locus_tag="ACG8LA_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HFQ0202870.1"
                     /translation="MSLLCKLVPERCIACGLCQIEAPDIFDYDEEGIVLFAQEPEAHQ
                     QFVMPEEETYVKKAYQKCPVRAILLENKI"
     gene            complement(50446..51183)
                     /locus_tag="ACG8LA_000541"
     CDS             complement(50446..51183)
                     /locus_tag="ACG8LA_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase"
                     /protein_id="HFQ0202871.1"
                     /translation="MKIFRRILIGLVIILGLLGGAGYYYIQQNTYEPSSEAQVLVKEG
                     KNKEDYLFFEGEKKNHGKSPLLIFYPGALVEPESYSIWAQDLAKNGFSVAIVKMPLDL
                     AVMGGNKADKVKEDFPNSDYVIGGHSLGGVMASRYVNKNHSDKHLKGVFFMASYPDKK
                     GTLTESAVPVLSITATKDKVLNQEAYQEAKQYLPERTEYVSINGGNHGGFGSYGEQKG
                     DGEAEISNADQQTVIVNTLENWLKKLK"
     gene            complement(51336..52676)
                     /locus_tag="ACG8LA_000542"
     CDS             complement(51336..52676)
                     /locus_tag="ACG8LA_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HFQ0202872.1"
                     /translation="MKKFVTEQHHEQALESLSELIRIPSVLDEADSGQGHPFGKKVIE
                     ALDKVLEISEKLGFRTFKDPEGYYGYSEIGSGDELFGILCHMDVVPAGDENNWETKPF
                     DPTIKDGWLVGRGSQDDKGPSIAAMYAVKALIDAGVEFKTRIRFIFGTDEENLWRCLE
                     KYNEKEEGITQGFAPDAEFPLIYAEKGLLQAYLTGPGTNEFSVKAGGALNVVPDAAPY
                     SGEKLSEVKEALKKHEFDFEEQGEGIVVLGKSIHAKDAAQGVNAISRLAIALSEVFDF
                     GPINFLGKLVQENATGEAVVGKTEDEQSGELTMNFASLEITPEQTKIGVDMRIPVTFK
                     KDDLVAKLTKTAEKYGLTYEEFDFLDSLYVPLDSELVKNLLGTYRDITGDMTEPFVSG
                     GATFARTMNQCVAFGAMFPDTPDFMHQANERWELSSMYKAMEIYAEAVYRLCAK"
     gene            complement(52913..54436)
                     /locus_tag="ACG8LA_000543"
     CDS             complement(52913..54436)
                     /locus_tag="ACG8LA_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HFQ0202873.1"
                     /translation="MEQTKKKKFQMPSAYTVLFIIIAVIAVLTWFIPAGHYSVDDAGN
                     IVAGSYERVQQNPQGLWDIFMAPINGMLGVPAGELTKETPAAIPISFFILVVGGFLGI
                     INKTGALDAGIASVVKKFKGKEKMLIPVLMLLFALGGSTYGMAEETIPFYALLIPVMM
                     AVGFDTVVAVAIVLVGSQVGCLASTVNPFATGVASQAVGISMGEGIGLRFLMFVILLA
                     ISIVYVYRYASKIEKDPTKSLVYNQRKEDMKHFDIEAIGRQEVITKKQKHVNVLFFIT
                     FGIMIISLIPWTTLNANFTIFESLTNWLTNLPVLGTVLGKSMLPLGDWYFPEITMLFL
                     VMSIVVAITYGMKESEFVSEFLAGASDLIGVAIVVAVARGIQVVMNNGLITDTILHWG
                     EQGLSSLSSSVFIIITFIFYIPMSFLIPSTSGLAAATMGIMGPMGEFAGVGKDLVITA
                     YQSASGLVNLITPTSAIVMGAVAIARFDVSVWWKFTGKLIAILFVAICVILGVAAMF"
     gene            complement(54814..55425)
                     /locus_tag="ACG8LA_000544"
     CDS             complement(54814..55425)
                     /locus_tag="ACG8LA_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HFQ0202874.1"
                     /translation="MKNTRVQKMVAVAMFAAIALVLQYFAFPIMPAFSFLKIDFSDIS
                     VLISMFLFGPAAGVATAFLRSVLHLLTTGFSPDNLVGDTASFLSTTIFTFPIYYFFSV
                     KKQHKGRNKFLGVITGTIALTIFMSIANYFVITPLYLMFLGLNATQMLGMSLANYVLI
                     GIVPFNLIKGFIVSAVFLVLHAQLLPWLSRKQHQFEQRHTAVK"
     regulatory      complement(55548..55673)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(55755..56471)
                     /locus_tag="ACG8LA_000545"
     CDS             complement(55755..56471)
                     /locus_tag="ACG8LA_000545"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HFQ0202875.1"
                     /translation="MERLQKVIAHAGITSRRKAEEFILAGRVKVNGQVVRELGIKVGK
                     HDTVEVDEVPIYQEEYGYYLLYKPKGVISAVADDKGRKVVTDLLPMVKERIYPVGRLD
                     YDTSGILLLTNDGDFAQRLTHPKHEVDKVYVAKVKGIATKSMLAPLTKGIKIEGRKTS
                     PAKFQILSVDPKTNHSIVELTIHEGRNHQVKNMLQAVGLPVQKLKREKYGDLTLQGLR
                     PGDYRELNKKEVSSLLNHSK"
     gene            complement(56477..57046)
                     /gene="scpB"
                     /locus_tag="ACG8LA_000546"
     CDS             complement(56477..57046)
                     /gene="scpB"
                     /locus_tag="ACG8LA_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HFQ0202876.1"
                     /translation="MTKLSELEALLFIVGEEGISNEELSGLLNLSEAEVTSLVKELKE
                     SYTQNSHSALHIFETESHYVLTTKKELAPLLKRYAQGTSNTLSQAAVETLAIIAYKQP
                     ITRAEIEQIRGVQVSGAVQRLAAHKLIEEKGRVEGPGRPILYGTTGYFLDYFGLKSLE
                     ELPDTQEMEISLEEDVSPDLFFDGMNKGE"
     gene            complement(57030..57800)
                     /locus_tag="ACG8LA_000547"
     CDS             complement(57030..57800)
                     /locus_tag="ACG8LA_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HFQ0202877.1"
                     /translation="MNELTEINIKLDVFEGPLDLLLHLIQQMEIDIYDIPIATITEQY
                     MNYIHTMKTLELAVAGEYLVMAATLMAIKSKTLLPVQEFVTDDEELWEEDPREELVTQ
                     LLEYRKYKYAAERLTEKAEERSLYYTKEPMNIDGLADAEKPLKRGQVKKIDLIRAMQK
                     ILERKKFSQKVEKTITPDDTTIEERMVFIEERIKRNAHGCTFDSFFESPSKSEVVTTF
                     MALLELMKKGQIIAQQKENYESIMLYPAVGDTEHDEIK"
     gene            complement(57797..58168)
                     /locus_tag="ACG8LA_000548"
     CDS             complement(57797..58168)
                     /locus_tag="ACG8LA_000548"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFQ0202878.1"
                     /translation="MLTHYRKENRKIAMGLLSFHKKLTGKTSLLKEIDTYESEDDYEL
                     FFFTPEGSTNIQGIIGIYWATNDQLIIHDISLNPSYRGENMGFQMLDELQEKYPDVSI
                     RATEITEPYIGKWLAKKKKKE"
     gene            complement(58187..59074)
                     /gene="xerD"
                     /locus_tag="ACG8LA_000549"
     CDS             complement(58187..59074)
                     /gene="xerD"
                     /locus_tag="ACG8LA_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009009 - site-specific recombinase
                     activity [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HFQ0202879.1"
                     /translation="MKEQINDYLHYLNIERGLSANTRQSYERDLEQYLHFLQEQKIAS
                     WQDVDRFLVIRFLEKLHEEKKATATVTRMISSLRRFHQFLRQERITDHDPMQHIDTPK
                     KAQKLPSTLTLTEVEKLIEAPDTTKTLGIRDRAILEVMYATGMRVSELIGLKLGDLHL
                     SLGLVQTVGKGDKERIIPLGDYAIQWLERYLDEARPLLVKDASEMHVFVNNHGKGLSR
                     QGIWKNLKQLVREAGIYKEVTPHTLRHSFATHLLENGADLRTVQELLGHADISTTQIY
                     THITKKRMTDVYKQHFPRA"
BASE COUNT        16125 a        12521 c        10097 g        20413 t
ORIGIN      
        1 ggagatatta tggaaattca acgtagaacc actaattttt tacatttagg ctcttttttt
       61 gcaactttga cgatcttatt ttttctatgt tattcatacc ttaagacctc acatgcgcct
      121 tctagtgcat taggctggtt gcttttggat cattctgata tcacagaagc cgaagaaaat
      181 ccgttttttt tgattttgtc ttctctttgc ggcttactgt tttctgttta tttcggtgcc
      241 tatttttttc atcgacatcc tggtacgtta aacgaagctt caagcgtatt gattgcattt
      301 aaaacgtttt cttttttagc aattcttttt tattcgttta atcacaatac gcttttcttc
      361 tttatcatga atggtttagt cgtgatttta tccattttta cttattttat tttttcactc
      421 atttttagcc aattgaaatg tccgctcttc tttcgattag ttcctgtcac ctgttttatt
      481 tacagcttgt tttccttttt tgtccttgct ttaatgccac tgaccaaccc ttcgacgatc
      541 caagtcgcag gaaatctgtt ggatatgctc ttcatcgtca gtctaggtgt atttatgtgg
      601 caaagaaaaa acaaacaaaa taaaaagcat tttgaagcct gactattacg acttcataaa
      661 tgctttttta gttttaaaca cttcaatcta aaagaataac ccaagattgg ataaattatt
      721 aatgactcgc cattcgtttc ttagtgattc tggattatca aatggacttc ctaatctaat
      781 cagctagttc ttcccataaa atgccatact tgactgaatc ataatattga ttatttaaaa
      841 atctaacttt tcttatcact acttcctttg tcattccaca tttctcacca tttttttgca
      901 ttcctttgtt tccagaccat gtagtgaatc taataggtgg tagataggca aaatactcaa
      961 ataattcttt taaccataaa ggaagagaaa ggctcctcct gcaagagtca gtataatttt
     1021 tgcttactgc tctcttaggt tttactcact aaaactgttc catattcttt gatataagaa
     1081 aatgcatgcg gtataaattt cttgctcagc tcagaaaaga tttgtcgttt aagaaaggct
     1141 atttcctcca ttgtcaatga aggatccaat gttggtaatt caatctcaaa attgtttttt
     1201 tcgacaatag gtaattctaa tgtgaatgat tcttcttcct ttatagtatt cgtcacaagt
     1261 agagactgat ggaaaatact aggccggcga tttttatatt tattcttacg tatcctgtca
     1321 acgataactt ctatttgatc aaaaaagtac gattcattta cgtctccaat aagttcggct
     1381 aattctttga atgccttcgt tacaggaagc tgattcttct gtacaaaaaa gtaattagcc
     1441 aaagtaagcg ggaagtgttc tatagaggaa agtgtgataa aacggtactt ctcatttcct
     1501 gcagttgtcc tcagcaattc tgtctctcgg ctgtttctta ctccataaaa atacgcttct
     1561 ttccgttcat cttcgaaaca atacgcccaa ataacttctc ccatcgctaa tttttgttca
     1621 tcaacagaga gtctcttcaa ttgttcagct atggtttcag cagccgaagt ggcttgttgc
     1681 aagtaatctt taggatcaaa tattggaaag ttcaaatgat atcttcgttc ttccctcttg
     1741 attaatcctg catcgatcaa taaatcaaga aaatgggaaa atttattttg cgaaaattct
     1801 tttttcaatt ctcttagaat cgtttcttgt tctcgatgtt catatagata atcggtcaat
     1861 gaagaaaaaa gcggatcatc ggtcagtttt tgataaaagt tttccttatt ttttgaataa
     1921 tagttcatat atgttctctt ttctatccgt tttattttac ttaaaaggct tttacgtaaa
     1981 aaggaggaag aacaagagtc ataattgact gttattctcc tccatttctt cggcctttag
     2041 tatgttctat gtttcttttt atatcaatcg cttatccatt cattttgaat gcttcatact
     2101 accatttgat tagctaaata cagccgtcaa ttgaggtacg acttgttttt tacgtgaaac
     2161 gacaccttta agcaaagcac ggttgttggt caaagttgtt tggaaagctt cttctacttt
     2221 ttcttttcct ttaccagcaa caagtaattc tgaatcactg tctaagatgt ttgtgacaac
     2281 taatacgaac agatcgtagc catttgcttt catttcatct tccattgctg cttctagctc
     2341 tgcttgtcga tccatcactt cattaaggtc cactgtattg acttgagcga tacgaacgtt
     2401 ggaactgccc attgggaaac tttttgcatc caaatcaaga agaaccgcag ctgatttatc
     2461 acttagattt gttcctgctt tcaacatttc aagtccataa gtgtttagat cgacttcagc
     2521 gattgctgca agttcttttg cagctgcttc atcttcaggc gtacatgttg gtgatttgaa
     2581 caacaatgta tctgaaatga tagctgagag catgattcct gcgatttctt taggaattgt
     2641 tacttggttt tctttatata gttttaaaat aatcgtactt gtacatccaa ctggttctgc
     2701 acgatagtac aatggattag ctgtttcaaa gtttgcaata cgatggtggt ctactacagc
     2761 taaaatattt acttcgctga tatctgaaat actttgttgg aattcattat gatccacaag
     2821 catgacatct gcattttctg ctttagctga ctctactact cgtggtgcag atagctgaaa
     2881 gtggtctaat gcgtattgtg tttcttcatt aggtgtacct agagcaactg cttctgtttc
     2941 tttacctaat tcattttgca agtgtgaaaa cgcaatggct gccccgattg catctgtatc
     3001 tggattttgg tgaccaaaaa ctaaaatttt tgacatgtca ttcgctcctt tgtgatttct
     3061 cctatttaat aatagcaaaa aaacggaaag aagcaatact tatcttcttt ccgatgcgac
     3121 ctatcgcgtt aaatattttg tatactcttc tgtatgaagc aatcgtttag cattttcgac
     3181 acgttctttt gtaggtggtt cgatcccttc taatggatat ttcaaaccaa gtgtttccca
     3241 cttgtatttt cccatcgtat gataaggaag aatctctact ctgtctacat ttgacaaggt
     3301 ttgaataaag ttgtctagtc ggatcaaata ttcatcataa tcacttcgct caggaactag
     3361 tacatggcga atccaaaccg gtttgttgat ttttgacaaa tattgagcca tttctaaaat
     3421 attttcattg tcccaatgcg ttagtttttt atgctcttca ttatcgatgt gtttgatgtc
     3481 aaataacagt aaatctgtat acttcatcaa ttcttgaaaa cgtgaaaaga aaggttcttc
     3541 atacgtaaaa ggttttccgc atgtatccaa tgtagtatgc atcttccgct cttttgcttt
     3601 tttaaatagt tcgatcaaaa aatcgatctg caatagaggt tctccaccac taacagtaat
     3661 accaccttta tctccccagt aaggtctgaa gcgttctgct ttatctaaaa gttcatctgc
     3721 tgtgtattct ttccctccgc caatattcca agtatctgga ttgtgacaaa attggcaacg
     3781 catgcggcat ccttgcataa acacgacaaa gcgcagtcca ggtccgtcta ctgaaccgaa
     3841 agtttcgata gaatgaacat agccgattgt tttttcttcc atttaagttc acatcttttc
     3901 tttgatttca ttttaagtac aagttagctg tcgaagcgaa gctttctgaa caaaattttt
     3961 cgcaattgcc gcttcgttat gtgtaaaatt tacagggacg gaacatacaa gtcctgcccc
     4021 tgtaaatcgt ttctttcaaa taagcatact gattattcga ttttgatgcg atggctattc
     4081 aacgtccttt cgacgctaag tcgaaaaact tttttcacga actttttaca ttctgtcgtg
     4141 tgaagttctc atcaagacat ctaattgttg ttctcttgtc aagtcacgga atttaactgc
     4201 ataaccagat acccggatcg tcaagttcgg atatttcatt ggattttcca ttgcatcacg
     4261 caataaatca ttactgaata cattgacatt caaatgataa gctccttttg agaagtatcc
     4321 atctaagaca ttacgcaagt tttcgattct tgtatcttgt tcttttccaa gacctgaagg
     4381 attgattgtt tgggtatttg aaattccatc caatgcacag ccgtaattca ttttagctgt
     4441 tgagttcagg ctagctaata acccactttg ttccgcattg taacttggat ttgctcctgg
     4501 cgcaagtggt tttccagctt cacggccatc aggagtattt cctgtatttt taccgtaaac
     4561 aacatttgaa gtaatcgtca ataatgaagt tgttggtttt gagttgcggt aagttttatg
     4621 acgtttgatt tgtcccatga agtattccaa gatccatgaa actaattcat ctgcacggtc
     4681 atcatcattt ccgtatttag ggaagtcgcc atccacttca aaatcaactg ctattccttt
     4741 ttcattacgg attgctttta cttttgcata tttgatcgct gacaagctgt ctgccgcatg
     4801 agagatccca gcaatacctg tagcaaatgt gcgttgcaag tcagaatcca tcaaagccag
     4861 ctgagctgct tcataagaat atttatcatg catataatga atgatgttca acgtattgac
     4921 atatagttct gctaaccaat ccatcatatt catgaagtta tgtttcactt cttcaaagtc
     4981 tagtatttct gatgtgattg gacgatattc tggtccaact tgggcgccag tcacttcatc
     5041 gactccgcca ttgatggcat ataatagtgt tttagccaag ttagcacgag cgccaaagaa
     5101 ttgcatgtct tttccgacaa ctgttcctga tacacagcaa gcaatcgcac aatcatcaga
     5161 accccattgt tcacgaagct gattatcatt ttcgaattga atcgaagaac tttcgatagc
     5221 gattctgcta gcatatgttc tgaatccttc tggaaggtgt tcagaataca aaacagtcaa
     5281 gtttggttct ggtgaaggtc ccatatttgt taatgtatga agcagacgga aatcattctt
     5341 tgtaactaat gaacgaccat ctaatcccat acctgcaatg gataaagtag cccagatagg
     5401 gaatcctgag aataattggt tatattcagg tgtacgcgcg aatttgacca tacgtaattt
     5461 cattactaag tggtcgatca attcttgtgc ttctttttct gtgattactc cattatccaa
     5521 atcacgttgg atatagatat caaggaatgc tgagatacgt ccgattgaca tcgcagcacc
     5581 attttgtgat ttgattgctg ctaaatatcc gaagtatagc cattggacag cttcttttgc
     5641 atttgcagct ggtttagaaa tatcatagcc atatttcgca gccatttctt tcatttgcgc
     5701 taatgcacga tattgttcag tgatttcttc acgtaaacga atcacttctt cactcattgt
     5761 atgataacca gtcatatcat gatctttttt cttttgttcc atcaaatagt cgattccata
     5821 caatgccaca cgacgatagt caccgatgat acgtccgcga ccgtaagcgt ctggaagccc
     5881 tgtaatgatt ttgtttttac gagcagcacg catttcagca gtataagcgt caaatacacc
     5941 ttgattatgt gttttgcgcc agtcagtgaa aatatgtgtc aattcatcgt ttggtgtata
     6001 gccattgctt tttagcgcat tgttagccat attgattccg ccgaacggca tgaatgcttg
     6061 tttcaaaggt ttgtctgtct gtagaccgac gattttttcc aaatctttat ccaaatagcc
     6121 tgcatcgtgt gaagtaatag ttgatacgat ttctgtgtcc atatcataga caccgttacg
     6181 ctcgaattgg atatcattta acttttgcaa ttcatcccat aatttttctg ttgcttctgt
     6241 tgggccttcc aaaaagctgt catcaccgcg atattcagtg tagttatttt gaataaagtc
     6301 tctagtgtct acgccttctt tccatttggt acctttaaat ccattccatt gctccattgt
     6361 atggacctcc taaatttctg ttttatgtaa cagtttttac gtgattagta taacacagca
     6421 ccctatcttt gcaagggttt tcttgttttt tatttaacaa tttttatgtt ttatttacat
     6481 atatttaaat caacgttgac ataccaacat ttaagcattg tgaacacttt catctttttt
     6541 tgcaaacgta taaggattta ttaaaaatga atgaaaaaga gacgccacct gtattaatac
     6601 agatggcgtc tcttcattaa aatactacaa cagttacgac tcgatgaaaa tctcaggagc
     6661 atcgataact tcgatgactt ctccaccttt tttctcatcc atcgcaaatg atccattcga
     6721 tgttcgatca cctataggga aatcagttgg gtcaatcgtt aactgctgcc ctttttgatt
     6781 catcaaggtt atttcttttg atcttccttc cgacatatag ataatacggt gcggattttt
     6841 tttcagctca cgcatgaccg tcactccccg cttcgcacgt gaagtttggc tgatttcttg
     6901 agcaagcatg cgtttaacag ctcctcgctg agtaacgatt acgatcggcg tatcaccttc
     6961 tgctaacaca agcagcccgt tgataatcct atctccatct ttcaaattca tagacttcac
     7021 tccagctgcc tttgctccaa caacgggaac atctgttaaa ggatagcgca aacccattcc
     7081 ttgatgcgtt actaagaaaa catctaagcc tggctgatct tctttcagat acacagcaat
     7141 cagttcatct tcttccgcct ttagcttcat acagctgagc ggacggctct tataggtgcg
     7201 ccatggttcg aactctgtca ttcgtgtttg cttgatcaat ccattcttgc tgatgaatac
     7261 aaatgttttc tctgcttgaa ttttttgata tgggaaaaca gctaaaatcg attcgtctac
     7321 agacagattg gagattgttt gagaaatgtg ctcaccagca tctttccatt tcaaatcggg
     7381 tagttcatgg acagggcggt agatcacatt tgctttattt gtgatcagaa gaacatggtc
     7441 caatgtactc aattcacctg agtatagcaa gtagtcgcct tctcgcatcc cgatttcttc
     7501 tggtttggaa gcactataag aacgaaggct tgttcgcttc acatagcctt ctcgcgtcac
     7561 actgacaatt acgtcttctt gtgccactaa gacttgcgta tcaattttga tttcttcgat
     7621 ttcgtcttcg attgtcgtta gacgagcgga agaataattt tttttcactt ctcgcaattc
     7681 ttttttcata acagagaaaa gctctttgtc atttgaaagg attttattca actctgtgat
     7741 ttgcgcaatc aagctttcgg attccttttg aagctctgtg atatccgtgt tcgtcaaacg
     7801 gtataattgc aatgtgacaa ttgcttctgc ttgttcttct gtaaattgaa agacgtcgac
     7861 taaattcttt ttggcgtctt ttttgtcttt actttcacga atcgttgcga ttacttcatc
     7921 cagaatcgat aaagctttca tcaatccttc tacgatatgc tgtctttttt gagctttggc
     7981 taaatcgaat tgactacgtt ttgttatgac ttgctttcga tgctcgatat aacttcttaa
     8041 aatgtctttc agtccaactt gatgcggagt catatggtcg atagcgacca tattgaaatt
     8101 gtaattgatc tgtagctcag tgtttttgaa caaataattc aaaattcctt gagcattggc
     8161 gtcttttttc aattcgacga caatttgcag acctgttcta tcactttcat ctcgtacttc
     8221 agctattcca tcgattttct tattcaaacg gatctcatcc atttttttca ccaaggtcgc
     8281 tttatttact tcatatggga tttctgtgat cacgatttgc tgtttattac ccttcattgc
     8341 ctctatcttt gttttcgaac gaagaataac ttttcctcgt cctgtttcat aagctttttt
     8401 gatttcatct tttccttgca agatccctcc tgttggaaag tcaggtccag gaatatattc
     8461 catcaatttt tcaaggctcg cttgtggatg atcgatcata tagattgtgc catcgatcac
     8521 ttcagctaag ttatgagtcg ggatttctgt tgcatatcca gcagatatac ctgtcgatcc
     8581 attgacgaga aggtttgggt atcgagctgg aaggactgtt ggttcttttt ctgtatcatc
     8641 aaaattccac acgagatcga ctgtttcttt ctcgatatct gctagcatct ctccacttaa
     8701 cttggataat ctggcttcag tataacgcat cgcagcaggt ggatcaccgt ccatactccc
     8761 gttattcccg tgcatttcga tcagtacttc ccgcaacttc cagtcttggc tcatgcggac
     8821 catcgcttca taaatactga tgtcaccatg aggatgataa ttccccatga tatttccgac
     8881 agattttgct gatttacgga atcctttgtc atacgtattg ccatctttgt tcatggcaaa
     8941 taatatccgg cgttgcactg gcttcaatcc atcacggata tcaggcagtg cacgttcttg
     9001 gataatatat ttggaataac gtccgaagcg gtcacccatc acttcttcta aagttaattc
     9061 ttgtacttct tgtcgatttt ccatcaggtg acctcctatt ctacttcaaa taactgattg
     9121 ttttcatttt tatctgctcg ttcttcatct aataaatcat tagaaactga aggagagatt
     9181 tcagtatcct cttttttatc taagatactg ccatcttctt cgagcgtaaa ttgcacgtga
     9241 ttttcgatcc attttcttcg aggttctact ttgtcaccca tcagtgtggt tactcgacgt
     9301 tcagcttgcg cagcatcatc gatacggacg cggatcaacg tacgggaagt cggatccatc
     9361 gttgtttccc acaattgttc cgcattcatc tctccaagtc ctttatatcg ctgcagcata
     9421 tatcctttgc cgactttttt aatcattgct gccaattcgt catctgtcca cgcatattca
     9481 atgacttgct tctttccttg tcctttggat actttatata aaggcggtaa cgcgatatat
     9541 actttcccag cttcaatcag cggtttcata taacgataaa agaaagtaag cagtaatact
     9601 tgaatatggg cgccgtctgt atccgcatcg gtcatgatga ttactttgtc gtaattacag
     9661 tcttcgatag aaaactcagg accgactcct gcaccaatcg tatagatcat cgtattgatt
     9721 tcttcatttt tcaagatatc ttgcatttta gctttttcgg tattgatgac ttttcctcgt
     9781 aaaggtagaa ttgcttggaa ctttctgtct cttccttgtt tagcagatcc gccagcagaa
     9841 tccccttcga ctaaatacaa ttcatttttc ttagggtttc gggattgtgc gggtgtcaat
     9901 tttcctgaaa gaagagattc gcctttttta cgcttcttcc catttcggct ttcttctctg
     9961 gctttacgtg ctgcttctct cgcttctctg gctttgattg ctttacggac caacatctgg
    10021 ctcatttcgc tattttcctg caaataaaag cccatttgtt cactgatgac gttatctact
    10081 acggtacgag caactggcgt accaagtttt tcttttgttt gcccttcaaa ttgcagaaga
    10141 ttttcaggta cacggataga aagtacagca gctaaccctt ctctgaaatc actaccttcc
    10201 agattcttgt cccgttcttt cagcaaacca acttttctcg catattcatt ataagatttc
    10261 gtcatcgccg ctttcatacc agcttcatgg gttcccccat cttttgtccg aacgttattg
    10321 acaaaagata aaacattttc tgaataaccg tcattgtatt gataagcgac ctctacttcg
    10381 ataccttctt tttctcctga aaaataaaca actggtgtca atgtatcttt ttcttcattc
    10441 agataatcaa caaattcttt gattccttct tcgtaatgaa aaatttcctt gactggttct
    10501 tctccacgaa gatcagaaag agagatttta acgcctttta gaagaaaggc agattctctt
    10561 aaccgttcgg ctaaaatttc atatgaaaat ttcgttgtac tgaatattgt atcatctggt
    10621 aaaaaatgga cagtcgtccc gtttgctttt tttgtttttc ctatcttttt caaagtaccg
    10681 tcaggtttac cgccgttttt aaatttctgc tgatactcta cgccatctct aacgatcgtt
    10741 acaattagcc atttcgataa ggcatttacc acactggctc ctacaccgtg cagtccacca
    10801 gaagttttgt accctccttg accaaacttt ccgccagcat gcagcacagt aaaaatcact
    10861 tcaactgttg gtattccgga agcatgcatt cctacaggca tcccacgtcc gctatctgca
    10921 acagttatac tattgtcttc atggatggtc acatcaatct cactgccata acctgataat
    10981 gcttcgtcaa ctgcattatc gacgatttca tagactaaat gatgcaagcc tcggctgtca
    11041 gtggatccaa tgtacatccc tggtcttttt ctaactgcct ctaatccttc caatacttgg
    11101 atggacgagt cattgtattc gttgtttact ttttttgcca aggcaaacgc tccttcaata
    11161 atactttgcg gcaaaaccgc accacgatta tcatactaga aaaggtcgtg aaaaaaaaga
    11221 gggtagacga gaaatcaatt ttaattatct cctaaccgct ttttcgacat tcccctctat
    11281 cgatcatctc ttctttgtgg tcatttttat ttttggtttt ctttcaactt accaagttca
    11341 atcttaatac aacgatccat tacgatatct gtacgtcctg cttttcttag catctcagct
    11401 gcttctttgt tttcaatccc taattgtgcc cagaacactt tagcatcagt tttcaaaaaa
    11461 tcacctgcta tttcaggtaa aaattcactc cgtctaaata catctacgat atcgattgga
    11521 tcatcgattt ctgtcaaatt cgcatagact ttctcgccta gaatttcttc accagccaat
    11581 aatggattta ctggtatgat tttatatcca ttgtcttgca atacctgtgc aaccatgtaa
    11641 cttgttcgtt ctggtttatt gctcaagcct acgacggcaa tattttttgc ttcttccaaa
    11701 tagttgaaaa tcgtttcttg tgttggattt tttacagaca tttctgccac cccttgcttt
    11761 tctttttatt ccatctatta tacttgtatc tttcattttt tcaattgttc ctgttaccta
    11821 ttcatgctaa aataaaggat agttttcaac ttgaaagagg gtaaaaaatg aaattgatct
    11881 tattacttat tttagcatat cttttaggtt ctattccttc cggtgtctgg attggcaaat
    11941 tgtttttcaa aaaagatatc cgacaacacg ggagcggtaa tactggaacg accaatacat
    12001 ttcgtgtatt aggcaaaaca gccgggattg ttgtcctgct tatggatatt ttaaaaggta
    12061 cattggctac ttgtttgccg atgatcttcc acctttctgg gattaaccct ctttggtttg
    12121 gggtatgcgc cattcttggc catacatttc cgatttttgc tgggttcaaa ggaggaaaag
    12181 ctgttgcgac aagtgcagga atgcttttag gatttaatcc tgtatttttt gtttattctt
    12241 gtatcatctt tatcgttagt ttattttgta caagtatggt gagtttgagc agtatgatca
    12301 gtgcagtatt gatcacttta tctacgatcg tccttcctta tgtagctcct gtgattttgg
    12361 ctaagcccaa ttggttactg acgatcattg cctttttagt ttcttccttt atcttttatc
    12421 ggcataaaga caatatcaag cgtatcagaa accatactga aagtcgaatc ccgtttggtt
    12481 tgaatagcag caagaaaaaa tcctgatact ttttcattcc aaagagataa aacgggagtg
    12541 tgacaaatcg atgtcacact cccttattac ttacaggata gcttttttac acaccttggt
    12601 aaacggtgtt ccctgctaac ttctcggtca caacctctta cttcactgtg atggaatatt
    12661 ttgtcttgaa gatttcatgg gcacctagtt gattgatccc tactttttcc atcaagtttc
    12721 cactactgtt caccgtgtca gcgattccgc accacggttc gatacaaacg aaaggcgctt
    12781 cttttggata aggagaccag atccctacat aaggcatatc tttatagctt aaagttacgc
    12841 tatgggaaga tttttcactt cgaatggcgt acgcatttag accccttgtt tcaaaaacca
    12901 aggcatcttg ctcaaaaagt tcacgattca aagccagatt cgtatttgtc tgacctaacg
    12961 tcttttgatc catatcgatg aatgggcctt tcaatggtag gcgtaatctt gatttcaatg
    13021 gagaaaatgc cagatagaaa tcttcaaatg acaatccttc ttcaagaggt acattgaaag
    13081 caggatgtcc accgatagaa aagaacattt ctttttcacc ggtatttgcc acttgataat
    13141 gaaccgtgat gccgtctcct cctaattcat agctgatcac taattcaaaa tcaaatggat
    13201 acttttctaa tgtctccggc gtactcctta agatgaaact agccatttct tgtccatgtt
    13261 caatgacttc aaaatccata tcccgagcaa atccgtgttg ccccatttga tatgttttcc
    13321 cttgataaac atactgatca tcttttaaac gtccaacaaa agggaataaa accggtgcat
    13381 gtctgcccca atacgctgga tcaccttgcc agatatactc taaaccatgt tcttttgatt
    13441 tcagactgat caattccgca ccgtgttcag cgatttcggc gatcagctgg tcattttgaa
    13501 taataacagt cattgccatt cctccaactt cgacttactt tttaaaatgg gaaggctgga
    13561 acaaacattt ctatctgccc cagtcccctt acttctaata actgtgtttt gctaactcgt
    13621 ctttaaaacg ggaattcaat acttttaaat aagttccctt catgcctaac gaacgagatt
    13681 caatgattcc agctgattcc aattttcgta aagcattgac gatcacagaa cgagtgatgc
    13741 cgatactatc ggcaatatta gaagcagtca gacgaccttc atctccatcc aatgcttcaa
    13801 agatagcttg tacagccttc aattcgctat aagataatgt gttgattgcc atttggacag
    13861 ccgttgcact ccgtacatct gcttcgatgc ttcgagactt ctgataaagg atctgcatac
    13921 cgacaaccgt agctccatat tctgctaaga ctagatcgtc atctgcaaac gattgttcca
    13981 tacgagataa gataatcgta cccaaacgtt cgccagctcc aaagatcgga acgacagtcg
    14041 tcagaccaaa tggatatttc tctcttgact ctaccggaaa tgcagtaata tcactagtaa
    14101 ttgggatatt agcttcagtt ttcatcaact gtgccactgt atcagtataa gattcaggaa
    14161 attgtttctc aacaaacatt gttttgattc gttcattgtt cacatcgtga cgttcattat
    14221 aacctagtaa tactccgtca cttcctatga tataggtgtt gctgtcaaga ataccaccta
    14281 gtgtgacagc cattttatcg taaggcaaat ctgcttgcat gtcaaaagta ttcttttgct
    14341 gcaaaagtgt gtttatcttg cgggttttcg ttagcaagtc tgtcattgtc gtcctccgat
    14401 tttttataaa atatagcgac ttaaatcttc atttgccgca attgagccaa gtttgtcatc
    14461 cacatatgct tctgtgatcg ttatttctcc catttgcata tctggtgctt caaataatag
    14521 atcttctagt agtttttcca aaatggtatg cagtctgcgt gcgccgatat tatctgtgtc
    14581 acggttgaca tcgaaagcga tttgagcgat ccgttcaatt gcttcttttg taaacgtaac
    14641 tgacacattt tctgtaccga tcaacgcgac gtattgtttt actaaagcat tatttggttc
    14701 ggtcagaatc ttcacaaaat cttcagctgt caaatcatct aattctaccc gtatcgggaa
    14761 gcgtccttga agttctggaa ttagatcact tggtttagac aaatggaaag ctcctgaagc
    14821 aatgaatagg acgtgatctg tttggatgat cccgtatttt gtgtttactt gtgaaccttc
    14881 gacaattggc aatatgtctc tttggacgcc ttctctggat acttctccag attgctgtga
    14941 tttagaagtg atcttatcga tttcatcgat aaaaataatt ccactttctt ccgctaattt
    15001 gattgcctca ctatggatat cagcatcctt gactaatttt gctgattctt ccttgatcaa
    15061 taactctaaa gcttctttga ctgttaccgt ccgttccact tttttcttcg gtgtcaaagc
    15121 acctagagtt tcatttaggt cgatccccat ttgctccaat ccattgttca tcattggtgc
    15181 aggtttcttt tggtcttcaa cttcaatggt tacttcacga ctatccagta aacccttttg
    15241 tagttgttcc aagactgtac ggcgattgat tcgaatatct tctgtcactt cttcttgcgg
    15301 ttcagcggta ttttgctgac tagcattaaa aagattcatc atttgttcaa attgattagt
    15361 ggattgtttc tgttcttttt tgataccagg taccaagatt tttaccaaac gtttttctgc
    15421 atttttttta gcacttgtgt atacacggct gtactgctct ttttctacga tttggatcgc
    15481 attttctact aaatcccgaa ccattgattc tacatctctt ccgacataac cgacttcagt
    15541 aaattttgtt gcttcgactt tgacaaatgg tgcattgacg atttttgcca aacgtcgtgc
    15601 gatttctgtt ttaccgaccc ctgtaggtcc gatcatcagc atattttttg gtgtaatatc
    15661 ttgttgcatt ttttcatcta actgcaaacg gcgatagcgg ttacgcaaag caacggcaac
    15721 agattttttt gctgcgtgct gtcctacgat atattcatct aattcactta cgatttgtct
    15781 tggtgtttgt tttaattcat acatatctac tcacctctta cagttcttct acgataatat
    15841 tatgattagt aaagatacag atatctgcgg caatatttaa cgcattttct gcaatttctt
    15901 tcgcactcat gtcgttttga gcatagtttt tcattgctcg ggctgcagcc aacgcaaaat
    15961 tccctcctga tccgatagct aagataccat catctggtgt gataacttct cctgtacctg
    16021 aaacaagaag catttcttta tcattcatta cgatcagcat cgcttcaagt ttttgcatag
    16081 attgctgtgt ccgccattct tgagctaatt cgacagctgc gcgttgtaga ttcccgttat
    16141 attcgtttag tttgccttca aatttttctt ctaaagtaaa cgcatctgca acacttccgg
    16201 cgaaacctac aacaacttct ccattgtaga tacgtcgtac tttctttgca gtgcctttca
    16261 tgacaacaga ttcacccatt gttacttggc catctccagc catagcaaat ttcccgtctt
    16321 tttcgacggc acagatagtg gttgaatgaa atggtgattc gaccatgttt gtttcctcct
    16381 aaatttgttc ttttccttat ttttacgctc ttggatggaa agaacgatag tttttttgta
    16441 aactttcttt tgttacatgg gcatagatct gggtagtcga taaattggca tgtcctagca
    16501 attcttggac tgtccgcaaa tctgccccat tatttaataa atgagtagca aatgtatggc
    16561 gcagcatgtg aggatggata tcactatcca aactgctttt tttgatcatt tgattcaaga
    16621 catattcaat tccagtaggc gtgattggtt ttccatgatg attcacaaaa acgatatcat
    16681 gctcttcgtg atattttgtc atcaatacct ggcggccttc cctgaaatat tcttgcagag
    16741 catcttgagc aaaagaacct agaggagcat atctctcttt gttcccttta ccatggatca
    16801 acatgacctc tgaatcaaaa tcaatgtctg ataccgacaa actgctacac tcacttaaac
    16861 ggatgcctga cccgtaaagg acttccagta aagcgcggtt cctcaaatcc aaaggactat
    16921 ctcctgctac gctgtcaaaa agtgcttgca tttcattttc ataaaaaaaa cgtggcagtc
    16981 tcaaattttt ctttttgaga tgaacgtaag aaaatggatt ttcttttatc acttcttctt
    17041 tgagaagata ctgataaaac gaacgtaggc tggctatctt gcgactgata gaatttctgc
    17101 tatagctagg acgatgatca gctaatgcac tcaaatagac acgaaccgta aaatattccg
    17161 ccttcagcag atcagcgtct ccagattcct ccaaaaaatg tttgaaatgg agaatgtctt
    17221 cttcatatgc ttctttcgtt ttttctgaat atcctctttc gacaatcaaa taacgcaaaa
    17281 atttttgttc ccacgtggct tctgtcattt tctcaccttc cttttgtccc agagaataat
    17341 ttagcacagc gtttataaaa agacaaataa attgtcagaa tttaaccaat atttctaagt
    17401 ttgttcacaa ttggcgcaat tcctcacatt ttgtttgaga aattcttaag aaaaacgcaa
    17461 gaaaaagagc gagactatcc gtctcaccct cttcatggag tttccttact catttgggat
    17521 tgcagttttt tctaattctg tttttattgc ctcattagct tttaaagctc gttgtgcaat
    17581 tgcttcatat cttgcttttt tgtctcgaat gcgctctggc agttcaggaa acagaccata
    17641 gttggcattc atcggttgga aatgttttcc ttccgcatga gtaatgtagt aagccatact
    17701 tccaatagct gtttcttgtg gaaactcgac tggttccatt tcttttgcta agcgtgcggc
    17761 gttgattcca gcaagtagtc cgctcgctgc actttcaaca tagccttcta caccagtcat
    17821 ctgacctgca aagaacagat cttcgcgttt cgttgattgg taagtcggtt tcagcaattc
    17881 tggcgaattc ataaagctgt ttcggtgcat cacaccatag cgaacgaatt cagcattttc
    17941 taacccagga atcatccgga aaacacgttt ttgctcgccc catttcaagt gagtctgaaa
    18001 gcccacgatg ttgtataaag aagctgcagc attgtcttga cgcagctgga taacagcata
    18061 aggacgtttg ccagttttag gatcttccaa tccaactggt ttcataggtc cgaaaagcat
    18121 cgttttgaat cctcgctgtg ccattacttc aattggcata catccttcaa aatatttttc
    18181 tttctcaaaa gatttaagtt ctgccacttc ggcattgatt agtgcctcat ggaaagcttt
    18241 gaattcctct tctgtcatcg gacagttcaa gtaagctgct tctcctttgt catagcggga
    18301 cttcaaatat actttatcca tatcgatcgt agctttgtct acgattggtg cagctgcatc
    18361 atagaaataa aaaccatctg aaccattgaa tgctttgatg ctttctgcta atggatgaga
    18421 agtcaaaggt cctgttgcta ctacggtgat tccttccggt atttcagtaa tttcttcgtt
    18481 tatcactgtt actaatggat gctctttgac ttttcgggta attgtttcag aaaaagaatc
    18541 gcggtcaaca gctaaggcac caccagctgg cactgctgtt tcatctgccg aagtgattac
    18601 taccgaattc aatcggcgca tttcttcttt caataaccct actgcattag ccaaactgtt
    18661 tcctcttaat gaattggaac atactagttc agcaaaatta cttgtgtgat gcgcctcagt
    18721 cgatttgact ggacgcattt catataaacg gacagggact cctgcttgtg cgatctgcca
    18781 agcagcttca cttccggcaa gccctgctcc aacaacattt accattttca atgaaagaac
    18841 ctcttttcta ttatttttgg atgtcttctt cgtaatctcc atttacacag actacttgtt
    18901 taccgccttt gactttcttc tcgaccagat atccgtcaca ttttggacaa tttctgccca
    18961 ctggtttatc ccaagaagtg aattcacatt ctgggaaacg ggaacaacca tagaatagtc
    19021 tgtttttctt agattttcgt tcaatgactt gtccttcatg acatactggg caagtcacac
    19081 cgatttcttt tacgattggt ttcgtattcc gacaatcagg aaaattactg caagcataaa
    19141 acttcccata tttccctaat tttatcacca tcggatgtcc acagacatca caatcgaatc
    19201 ctgctggttc atctttgatt tgaatttttt cgattttttc ttccgcattc gtcagttctt
    19261 tttcaaacgg tttatagaaa cgatcaacca ctttgaccca cgcttccgtg ccttcttcaa
    19321 ttttatccaa atctccttcc atttctgctg tgaaatggat atcgacgatt tgagggaaga
    19381 attcacagat taatgaattg acaatttctc ctagttcagt cggctcaaat cttttttgtg
    19441 tcaattttac atagtagcgt ctttggatcg tatcaagtgt tggtgcataa gtggaaggtc
    19501 gccctacccc gttttcttct agtgcacgaa tcaacgtagc ctcactaaaa cgtgctggtg
    19561 gttgagtaaa atgttgtttt ggttcaatat caacagattg gactacatcg ccttcttcaa
    19621 gttctggaag aatattttct ttctcttctt tgccgtcatc tctaccttcc acatacactt
    19681 gcatgaatcc tttgaatttg atttttgaac cgttcgcaat gaagatgaca ccattttgtt
    19741 ctaatgtcac tttcattgta tctaaaatag ctggtgtcat ctgactagcc acaaaacgtg
    19801 accagatcaa tgtataaagt ttcaattgat ctttatctaa atattgtttg agttcatctg
    19861 gtgtacgaag cacactcgtt ggacgcacag cttcatgggc atcttgtgcg ccttgagcat
    19921 ttttgatctt tcggtgatca tgtctagaaa attcttttcc atacgtatct tcaataaatg
    19981 ctgcggcctc tgcttttgct gtatcggcaa tccgggtaga atcagtacgc atgtatgtaa
    20041 tcaagccgac tgttccttgt ttacccaaag tgattccttc atataattgc tgtgctacca
    20101 tcatggtttt tcttgttcga aagtttaact tacgggcagc ttcttgttgc aggctacttg
    20161 tagtgaaagg attcgcaggg tttcttttgc gctctttctt ttctactttt ttaacttcga
    20221 agtctgttcc atcaattcta gcagtgactt cttttacact ttgtgcatct ggtaatttct
    20281 ttttcttacc gtcgattccc cagaaatttg ctttgaattt cttgcgagct tttttaaaat
    20341 taccgtcgat gctccaatat tcttctggaa caaattctcg gatctctttt tcacggtcaa
    20401 taataatttt taaagcgaca gattggacac gtcctgcact taaccctttc ttgaccttac
    20461 gccagagaat aggactgatc gaataaccaa cgattctgtc taaggtacga cgagcttgct
    20521 gtgcatctac taaatctaca tcgatcgttc ttggttcctt aaaagctgct ttgactgcgt
    20581 cttttgtgat ttcattgaag accacccgat ttttttcttt cagatccaac ccaagtaggt
    20641 acgctaaatg ccaagcaatc gcttctcctt ctctatccgg gtcacttgcc aagtaaactt
    20701 tttgagcttt ttttgctgcg gctttcaggc ttttgatgac atcgcctttt ccgcgtatag
    20761 aaatataatg gggttcataa ttgttttcaa aatcgatacc cattttactt ttcggtaaat
    20821 ctcttatatg gccaacactg gccattactt tatagtttcg tccaagatat ttctcaattg
    20881 tcttggcttt tgcaggtgat tctacaatca ctaaatattt atacgccatt actgaatgga
    20941 ctcctttcca ttgtcgtgtt cctactatta aaagaggatt catacaaatc gtagctaatc
    21001 atatccattc agaaaacgtt tgtcaagaaa agcaaatgaa aagtatggtg ttattcttta
    21061 aattctgcca agatatcttc acccgaaacc gtgcaaactg caccgtcttg gatcaaatga
    21121 tgacatccgg tagaatgttc tgttaaaata tttcctggaa cagaaaaaac tgttcttcca
    21181 agatccaatg cttgctgtgc tgttatcaga gagccgcttt ttttcttggc ttcaaagaca
    21241 catgttcctt tagacaaagc tgcgataatc cgatttctca ttggaaaaca atgctttttc
    21301 gggccggatt gaggaggata ttcactcaaa agaagatgat catttgcaat cacctcttgc
    21361 aagtcacgat tttcagcagg atagacttgc tctatccctg ttccaatgac tgcgattgtc
    21421 cgtccaccat gagagattgc tgcttggtga ccgtatgtat ctatcccttt cgcgcagcca
    21481 ctgacgatca catatccagc ttctatcact ggttttagta aataataaac tgtttttttg
    21541 gctaaagcag aagtgtgtct tccaccaaca acgcttaaca tgttacaaga aagtaaagat
    21601 agatcaccat tataaaacag tacaattggc ggataggtca agtgaagcag ctgaggggga
    21661 tatttgggat caaagcaagt gataaacgac tgtttcgatt ggattttgcc ccagttagcg
    21721 tgaatttcct gccaactttt gcgaaacagc tcccggtgtt tggttatttt acctatctta
    21781 atgatgtctt caaatccgat ttctttataa ggatactgca tcatccagtt agcaagtgcc
    21841 cattttcctt gactactgat tccttttgta taagcaagtt tcaataaatt ttcttctatt
    21901 tgatacatca taaaaccgcc tttcgtctct ctttctaata agatacgtaa aagcggctgt
    21961 tttttattgt aaatattttt ttacaggtgc aaaactttta cgatggattg gcgtaattcc
    22021 ttgtcgttca agtccttcta agtgttcctt tgttccataa cctgcattat gcgagaaacc
    22081 atatccagga taaagcacgt catattcttt catcaattgg tctcgatata ctttagcaat
    22141 gatacttgca gcagcaatcg acacagatcg tgcatcccct ttgattattt tttcctgctg
    22201 aataggcaaa tccaaggtca tcgcatcgat caacaaatag cttggtacaa tggacaattt
    22261 ttctactgct tggatcatcg ctaatttact tgcttcataa atattcacat catcgattgt
    22321 ctgctgatca acgatcccga tcccgattgc cagggctttt tcttgaactt gttgataaag
    22381 aagttctcgc tttttctctg ataattgttt ggagtcattc agccctaata tgatctcatt
    22441 tttcggcaag ataactgcag ctgccacgac aggtccagct aatggtcctc ttcctacttc
    22501 atcaatgccg gcaatccatt ggtgaccttg tgcgtaccct tgcttttcaa agcaaaacat
    22561 ttcttcatat ttttccttaa ttaatgcttc ctttttcaat cgtcgttcaa aagaagccag
    22621 tgcttgctgc acgcctttgc gtggatcatt tcttaatgat tctagtgtag gatcatctat
    22681 tctctgtatg cttttcaatc gttctttgat actttggatg gattcagtca tcactttttt
    22741 gctccatttc ttcgcaacga tccagtgtgt atcgtccaag ttttccttga cgaatatcat
    22801 gcacgactaa ttcgctgcca cgatcatagt cttctttata cccacgtttt gctgtaatat
    22861 ccatcagtaa ttccggtgcc aatttttctt cttgctcgat tgataaacca taacgatcgc
    22921 tgattcttcc tgaataatat cgggcaaaaa agtctaatcc gtaaatcgct aaatcatcta
    22981 aatggacaag ctggtctttg atcgcgcctg tcagcgctag ttttttgccg atttcttcat
    23041 cttcaaattt gggccataaa atccctggtg tgtctaacaa ttccaactca ttacctaaac
    23101 gaagccactg ctgacctttt gttacgccag gcttatttcc tgtctgtgca attttcttgc
    23161 ctactagtcg attcatcaac gtagatttcc caacatttgg aatacctaag accattgccc
    23221 gaatagcgcg aggcttgatc ccccgagcag catctcttgc ccgtttttct ttcaatgctt
    23281 ctttagccgc aggtactaga cctttaattc ctttactttc ttgtgccgtg atagctaatg
    23341 caagatggcc ttgtttacga aaatattctt gccacagctt tgtctgttgt ggatctgcca
    23401 gatccgcttt attcaataaa acaaggcgag gtttttgctg aatgatctga tctagcattg
    23461 gattacgaga agataaaggt aatcgtgcgt ctaccaattc aaatacgatg tccacatatt
    23521 tcattttttc agaaacttct cgtcgggctt ttgccatatg tcccggaaac cattggatgg
    23581 tcattgttct ctccattcct ttcataccgg aatattcccc ggctttactt gtttttttct
    23641 ttttcaatat aaattcactt ttttattata aagaaattcc atctattagt taagtgaaag
    23701 tgaaccagtc ctcattctat cacatcttca cttttttgat gatgcaaatt tttattttgg
    23761 tttctatata tgaatctaaa tttttgacag cgtttcctaa ataagagatg atagacgaac
    23821 aaaacagaaa ggagacgaaa caaatgaata gtatggtttt tgttaatttt cctgttgctg
    23881 atgtcaatcg ttccgttgct ttttatgaaa agctgggttt taaaaaaaat gaagaatttt
    23941 ctactgaaga agctggttca atggtatggg atgacacttt ttggataatg cttctctctc
    24001 atgattttta taaaaaattt ataaaagata aagaaatagc tgataataaa aaaacaagtg
    24061 gtgctttgat ttcgtttagt gttgaaaatg cggatgaagt aaaaaaattt gctcaaattg
    24121 caaaagaaaa tggtggtact ttccacgaag tagatatggg aatgcctgaa gaagaaatgt
    24181 tttcattaga agtccaagat ctagacggaa atacattaga acccgtatgg atgaagatgt
    24241 aagcagataa ctaatctgac gttttttata acaaaaaaac aaaggcggat gatacgataa
    24301 gtattctccg cctctatttt ttttattcgt acaatctctt ttttacagtt tataaaagca
    24361 gtcttctcac ccttttttta attgttagat gccagtgtat gtaaatcacc aatgtgtcat
    24421 gacacattgg tgattttatg gtatcctttt attattaact gacaaaggag agaatatttt
    24481 gaacactttg attgcaaaag acgtttttag attgcccgaa atgaatgcaa gattgttgtc
    24541 gacctctgct cttttattag cccttgatgt catcttatac aagatagcga ttggtcctgc
    24601 ttattttcaa atcacattcg gatttttaag tatggcgctt atgggttatc tatatggacc
    24661 gatctgggct ggtttgcttg aaatgttgtc gaacacttta aatttcacga tatttggttc
    24721 aggaacgttt caagctgctt ttcttatcac ggctttcctt ggtggattta ttaatggctt
    24781 atttttatat cataaaaaga taaacctgcc ttccgtcatc gctgcccaat tattgattat
    24841 gatcccagtc agccttttta tcaattcttg gctgatgtct gttttgtttg gtgcagattt
    24901 caaagtaatt tttctaggta gattcatcag gaatatgatc caaatcccta ttcaaataat
    24961 ggttgtttat tcatttatca aaactttaga ggctagaaaa gtgtttaaac gagctgtttg
    25021 attttacgta ctaaggtagt aaactgattt tggattaaac aataaagcgt gcagtctcaa
    25081 cagactgcac gctttattgt ttctcactgg atccatttta tttcatcaag tggataatag
    25141 acaaatcttg ctttacctag aatatcagtt ttattgatcg tgccaaacga acgactatct
    25201 tttgaaactc ttcgattatc tccaagtaca aaataattat cttccggaag cttggattgt
    25261 cccgttagct cttgtagtgt aaagtccgtc gtataggatg catttgcatg atctgatttc
    25321 aggtttttag ttagataagg ttccttaact actttcccat tgatcttcaa ttgatcattt
    25381 tggtagctga cattttctcc tggaagaccg attactcgtt tgatataaat cgtgccatct
    25441 gctaattgaa aaacaacaat atcaaatcgt ctgatctccg aaaatttttc catcacaacc
    25501 atatcacctt gcttcaacac gttttccatt gaattgcctt ccactggtac cgggatgaat
    25561 aaaaatcccc gcaacatgaa cgcaaggaat acagaaacaa gtaagtattt gaatacaagc
    25621 cagaagcgat taatatagcg ttgttttttt gtcaatctct atcaatccat ccctcttttt
    25681 ttcattcttt ctttattata agaaaaatat caaaaaaatg cgactagata gctgaaataa
    25741 aaataattct ttcaattagg ctattggaca aaaaactttt ttgatcataa agtacaaaac
    25801 tatctcttat atgtcatgat tattttctaa atatttttcc catgcttcgt caaagatatc
    25861 catggacggc aaatagtcga cattcagttc cagataatta gaaatttctt cgtagctaga
    25921 gctgtgctta ggaaattgga tgtctttacc ggcttctgta gcgaaaacag ataaagcatc
    25981 atgtgtgcca ccgcctcgca gtgtcattaa ataatgaaaa aagcttcgat tcacccttcg
    26041 ttcctccaat tttcttcgat aaaggcagcc cggcgtgcat ggtttctttt aaaattttca
    26101 ggatgctttt tataatactc ttgatggtct tcttctgcta gataaaatgg ttgggctggt
    26161 tcgatttttg taacgattgg ctgttcgaaa cgtccacttt cagctaactg tttcttactt
    26221 ttttcagcaa tgatccgctg ttcttctgtc aaataaaaga tcaccgggcg ataattgtca
    26281 ccgcgatcct cgaattgtcc gaaagcgtca gttggatcag tttgctgcca gtaaagttct
    26341 actaattgtt catatgaaat caatgttgga tcatagataa tctccactgc ttctgtatgt
    26401 ccagtcgttt ggctttttac ttgttcataa gtcggatctg gtacatgccc tccagtatat
    26461 cctgacatca ctgtatggat accaggaagc gtgtcgaaag gctggatcat acaccagaag
    26521 cagcctcctg caaatattgc tcgttccatt atgattcccc ctctaatact actcatccga
    26581 tgatttttta ttttcttttg tcttgctttc agtactgctg gtgctagttt tgttggtatt
    26641 tgagttgttt gaagcatcag aggtatcttt tggcaaatat agactaaacc gaatgtcatc
    26701 atttactaag tcgattttat ctgctttaat atacatcccg ttttgcattc ggaattgatc
    26761 caacctaagc atgatagtca gatcatctgt attgacttcg atccaatctg gtaatttata
    26821 gtttctcttg atcatattca tcacatcttt gattggcaaa ctcaatgttc cgatagaaag
    26881 acttctagct tttagttgga catttccgtt ttccatcaca tacggatcaa aatataaata
    26941 gaaatcgata ggaaaaccta gtacttcgaa agtaccattg agtagtgctt cattttccaa
    27001 ataaaattta tattcaatat cactatcttt ttgatactca ctaaggaaaa agctgatgat
    27061 ttgattgact ttttctttat ttgaattgat cgttaagaca ggatctcctt gtctttccgt
    27121 aagagctggt atttctggga gttctggttc ccgattagca aaaatacggc tgcctaaaaa
    27181 tacggtcgaa ccaagtacta ccccaagaag gataaggaag gcgaatttcc agtaatttgt
    27241 tttctttgtt ttgtttgaag atacgtcaga tcttgttttc atgtttattg atcatcctcc
    27301 ttctctaacc attggttttg tgtctcgatc agctgatctc tcactgcatt tgccatcaat
    27361 tgataaccta aattatttgg atggaaatga tcttcttcat agagcacatt atttttgatg
    27421 ccatttagat tttctgtcgt gctagttgtt tgatctgttc cttcttctgt gacacctact
    27481 tcctgattca atccttgata aagcaaatca ttgattggga taaagtagca gttcggcatt
    27541 ttttttgtca ccgtttctgt tcctttgttc caattgttaa caattgtctg catgtcagtg
    27601 atctcaggaa agttcaaata aaatggattg tagatgccta aaatgtaaat aggtgcggtt
    27661 ttattgaggg atcgaaattc ttccaatagt tctgtgacat tttcctgata gtttttcagt
    27721 ggctttttaa aggaattgac cgttaacccg aataaattat tttggataac tttcatcaaa
    27781 tcattaccgc caacagtcag tgtgataaaa tcagctgttt tgatattgtt tcgaatttct
    27841 tcttttgttt ttactcgctt taagatctgg tcacttcgtt caccatttac accatagttt
    27901 tctgtttcaa ccgcggtcaa attataacgg tcttttagat catttgcgac aaggggaacg
    27961 aatcctcctt gcttggtttg atctcctact ccttcagtca gcgaatctcc gatagctatg
    28021 tagtgaagtt tttctttttt atttggatct tctctcacag tagttactgg tttcattagt
    28081 gggccagctt tcggtataga agcagctaaa cctgcataga tgatgatcgc aattaataat
    28141 gggaacaaaa cgaggatcaa atgtcgtttc gttaatttca ttttttcacc tcttgtattc
    28201 gattggttct aatgttatca aaaattttat caaaaaggta gtctttatga aaaaagaaaa
    28261 caattatttt cctaatttta taaagaaaaa gagaataagc tgcaagcctt tcaggctgag
    28321 ggcttatcct cttttcgact aatctacata atacatgatt gcaaacgcgt ctttaccagt
    28381 atgcgtagcg ataaccggat tcgtatgcag tacagggata tgcatgtccg ggaataattc
    28441 ttgcaaaccc tctttgaatt cttgcgccaa ttcttttgca tccgcatgtg aaataccgat
    28501 ttgtcgcaca tttggcaatt ctttcagttc atttttcaaa ttattaaacc atttatcgaa
    28561 cgttttcttt cctcgcccct tagttacagg gattaattca gaatgggcga aattcatcac
    28621 cacgcgtatg ttcaaaacac tagacagcaa accagttgtt cggctgattc ttccaccttt
    28681 taccaagtta tctagtgtgg atattccgat gtataatttt gtattgtctt gtactttttt
    28741 gacttcttca aggattttct ctactgtttt accttctttt gctaattcag ctgctcgaat
    28801 tacctgaaaa gataatcctt ggtcagtggt atcactgtcg ataaccgtta ctttcgtttt
    28861 tgttagatta ctggcttgtc ttgctgcttc tactgttcca ctcaagcctt ttgtcatatg
    28921 gatcgaaatc acttcactgc cgtcttctcc tagctcatca tacatcgaga tgaattctcc
    28981 aattggtggt tggcttgttt tgggcagatt ttttgctttc gccatcattt ccataaatct
    29041 ttcgccgtct agttggtcat catcgggata tactgttccg tcgatcatga tggatagcgg
    29101 catgacacga atgcctaaag catcgcgtac atttttttcc atcgtacatg aagaatctgt
    29161 tacgattttt acatttgtca ttattttctc tctctctttc tttaacaaga tgccttattc
    29221 atgttaaact acatgtaaga caatttctat ttttagtata acagacaaat aatgattttt
    29281 cattaattac acctagtaaa ggagccgttt tcatggaaaa aacgaaattt aatcgaacgt
    29341 atgaaatatt aaatgaagtg tttaatgcag tcacccatgg aattgggact ggattgagta
    29401 tcgcgggact agtggttctt ttagtaaaag gtgcccactt gcattcctcc ctccatattg
    29461 tctcttatgc tatctatgga tcgatgatga ttcttttatt tttaacgtct actttgtttc
    29521 attcattgat ttttacaaaa gcaaaaaagg tgttccaagt attcgatcat agttcgattt
    29581 ttcttttgat tgcaggaagt tatactcctt tttgtttgct gagtatccga ggatggctag
    29641 gttggacttt atttgtatta atctggttgt ttgcgattct tggcattata tataaagcgt
    29701 tgacgttgca taaacgggag agagtatcaa aagtatctac gatcatctat atttttatgg
    29761 ggtggctctg tgtcgtggct gctgttcctc tttatcactc tcttggaatg actggtgtta
    29821 ttttgatggt agcaggcggg ctttcttaca cgataggcgc attcttttat agcttgaatt
    29881 ctatccgcta tatgcatgtt gtttggcatt tgtttgttat gttaggtgca ggttttatgt
    29941 acttctctgt tttattcttt acttaataaa aaaaataaag ctatggatgg gacagctcta
    30001 aataacagct agtctatcca tagctttttt atatcgtcaa ttcgcctgtc ccgcttttta
    30061 caggattctc attacgctga tacgtttcaa attgatgcgg ataacgattt ttttcatcca
    30121 tttctccttg actagtattg atcagtgacc aatcagacca gtcaacaggt ggaaaataag
    30181 catctccatc gaatacatga tggatgactg tacggtataa tatcgtacaa aatggcagaa
    30241 attcttgata aacagctgac cctccagcga tgaaaaagat accgtctgtt tctttttcca
    30301 gagcaagcac gtcttccaca ctatgcatga catgcacgcc ttctgcttta taggaagaat
    30361 ctctcgtcaa aacaatcgtc tgacgattcg gcaacggacg gctacccatc ccttcgaatg
    30421 tttttcgtcc catcactagt gtatttgctt ctgtcatttg tttgaagaat ttcagatcat
    30481 ttggcaaacg ccaaggaaga cggtcttctt ttccaatcaa tccgttttca tcctgtgccc
    30541 aaattgcagc taacattttc tcatcctttc tgattctaaa cagcgatagg agctttgatc
    30601 gccggatgtg ggtcatatcc ttctaattgg atatcttcca tctcaaaatc aaatactgac
    30661 tgcttttcct gattcaaaac taaagtcgga aatgcgcgta tttctcggct caattgttct
    30721 ttcatttgtt cgatatgatt gatataaaga tgagcatctc ctaatgtgtg aacaaattcg
    30781 ccaaccgcta aacctgtttc atgtgcaatt aggtgagtca gcaacgcata acttgcaatg
    30841 ttgaacggaa cgcctagaaa cacatcccca ctgcgttgat acaattggca gcttagccgt
    30901 ccctcttgaa cataaaattg aaacatcgta tgacaaggag gcaaagccat gctaggaaca
    30961 tcttccggat tccatgcaga aacgatcaat cttctagaat caggagtctt tttgattgct
    31021 tcgatcactt gtttgatttg atcgataaag ccaccgtctt ttgtttccca gtgacgccat
    31081 tgatagccgt agatgtgtcc aagatcgccg tatgtttcag caaaggaatc atcggttagg
    31141 atcttctcgc aaaaaagctt gctctgcttt ttatattctt cattgaattc aggatctgtc
    31201 aaacatctat ggccaaaatc agtcatatct ggtccattat agtctggact tttgatgtag
    31261 cgttcaaatg cccattcatc ccaaatatgg tttttatttt gtaatagata gcggatattc
    31321 gtatctcctt ttaaaaacca aagcaattcg cttttgatca atccaaaagg tactcgtttc
    31381 gttgttaaca aaggaaaccc tttttgcaga tcaaaccgca tttggtatcc gaataagctt
    31441 aatgtgcctg tgcctgttct gtcttcttta cgatgccctt cttccaacaa ttttcttcct
    31501 aagtcaagat acgcttgttc catccttttt cctcctaatc ttctacccat tcactcaagt
    31561 attcccaccg tgccattttt tcttcaagtt gtgcttctgt ttcagatacg tcgttttgca
    31621 attcttgtaa tcgagtgaaa ttatctcctt gatgattcat ctcttcttgg agcaatgaga
    31681 ttttttcttc aagttctgca atctcatctt caatcgtttc ccattctttt tgttccatgt
    31741 aagataattt cttcttttca gcaggttcct tgctctgtat ttttggtttc gctttttcag
    31801 caggctgctg ggtctctttt tgcttcagta aataactgga catgtttccg taataaagtt
    31861 cttgttttcc gtttccttgg aatactaata acttatctgc taccttgtcc aagaaataac
    31921 ggtcatggga aacagtgatc acagcacctg gaaaacttct aaaataatct tccaaaatcg
    31981 tcaatgttgc tatgtccaaa tcattggtcg gttcatccaa taataaaaca ttaggttgct
    32041 gaatcagcag tttcaacaaa aataaccggc gtttttctcc gcctgaaagt ttgcctatca
    32101 gtgtcccatg cataaatctt ggaaataaaa atcgttcaag taattctgct actccgattt
    32161 gactgccatc tgctgttttt gcttcttcag cagcttcttg taagtaagca atcatccgtt
    32221 tatctggtgc catttcttca ttttcttgtg tataatacgc aagatgaacc gtttcaccga
    32281 tagacattgt accgctatcc aggggaattc tgccagctag aatattaagc aatgtcgatt
    32341 ttcccgcacc atttttacca gtaataccta gtctttcccg agattgaatc aataaatcta
    32401 aatgttctag cagtgtttgg tcatttatac ggtaactgcc atctttgatt tccagtactt
    32461 ttttccctaa acgttgtgtc gctaggttca gctctaaatc atcttcttgg tttacttggt
    32521 acaagttctc ctttagatct tcgaaacggt tgatccgtgc ttgctgcttg gtgccacgtg
    32581 cctgtacgcc agccctcatc caagctaatt cctgtttata aagccgcttg cgcttttctt
    32641 cttgttctac ttctacacga tcacgttctg ctttttctaa gacgtaagct tcataatttc
    32701 ctttatactc gtataatttt ccaaatgaaa gttcgaagat tcggtttgct actctatcta
    32761 gaaaataacg atcgtgggta accatcaata gtgcgccacg gtattgtttc aaatagtttt
    32821 ccaaccactc gatcgcttca taatctaaat ggtttgttgg ttcgtctagt aatagtaaat
    32881 cgggttcatc aatcaacact tgcgccagac taactcgttt tttctgacca cctgataaag
    32941 tactgatttt tttatctaat tcactgattc ctaatttttg caaaataatc tttgcgttgg
    33001 tatctgtagt ccaagcatct tctttattca tttgttcttc tgctttagca taacgttttt
    33061 gcacatcagg gtcttctccg ttttccccta gttcgatcaa tgcttcctca tatgctcgaa
    33121 cagtttggat caaggggctg tttccttgaa agactgcttg gagaacagtt aattcatcgg
    33181 aaaattcagc tgcttgagaa agataaccaa tacggtaatc agttggataa aacactgttt
    33241 gccgatcacc gtcgctgcta tcgataccgg caataatatt taagagactt gttttacccg
    33301 tcccgttcgt cccaatcaac ccgatacggt ctttttcgtg gaccaaaaaa gaaatctggt
    33361 caaacaaatc tttttcacca taagtttttt tgaggtcagt tacttttaat tctttcaaca
    33421 tgttccctcc ttatcttgga tattgtatca taaaaatagt gaacttcagg aaaatttttt
    33481 tggtatttgt tctttttgtg ttctcaaaaa aagaacagga ccgattcgat cctgttctga
    33541 tatgttttgt tttttataaa acttgaaaat ttttaccttt ttattttatt ggactcgttt
    33601 tttttgactt tgctcgaaac gcaaatcgga aagaaaagtt atcagatggt ttgttcatcg
    33661 tataagattc taacaaattg atattcctgc gatagctgtt cgcagaaaac gtcgtgattt
    33721 tttcagcaac ttcgtattca tcaatgattt ttctttcaag ataataacct cttagcattt
    33781 ttttcgtaaa cagactatct tgctggatca tccacgaaga aatcaaattc cccgagttca
    33841 tttttattcc ttcaagtttg cgttgctgga taaaaaattg aaccatcgtt tcatcataaa
    33901 tatcagtcaa gttatctaaa ctttcaataa tcaactgagt atttttttga tatgtctctc
    33961 tgatttcttg gatatcttca tcactaataa atgtctgacg atcagcatat cttctttgcc
    34021 aaaacatttt cggatggaga acgattcgca ttaacctacg gacaacaatg aaccaaaagc
    34081 cgataaaaga caaaatctgg cttgtgatag aatgttcgaa tcgagaaaga aaacgggagt
    34141 aaaaacgata accattagaa gaaagcttgc ccgaacgata actttcatcc aatccatccc
    34201 gttcgatcga caaaatcagt gcttgtattt cttgtacttc ttgcttttca tcatcggtta
    34261 aatcttccaa gtacagatca cgtatccgtt cttgataatt ttctatcact gcttcagtgg
    34321 ctaaaaattc ttttgtatta cgatcaattt cctttatttc ttttcgcaaa acttcaacga
    34381 cctcttctaa aatcatcaaa gcattcaaat ccgtgctttt cgcttcctct gtttccgtca
    34441 gcataggcaa gacaatgatc cctatgacca aagtcactaa gatgacaccc gccgtcagaa
    34501 acaaaagcaa agaccgctgg taaaacatca tattattgat tgaaaatggc aaaataaaaa
    34561 tcgtagccaa actgactgtt ccctttacac cgccaaatgt taagatcaag atctcgttca
    34621 actgtttttt gaacttttta ctgccatctt tgaatacata aaaaagactg atagaaatga
    34681 atctgatcac aaaaagcatg acagagatta atacgataat cgctaataaa agaccgtttg
    34741 gatataaacc gtctccccat actggcgaga acacttgcgt caattcgatt cctaaaaata
    34801 taaatactaa tgcattcagt gtaaaagcaa tagttgtcca tgtactgtgg gacaagctcg
    34861 acaattctgc atcaaacaca gagattttcc taaaaccaga agcttggaga atacctgctg
    34921 ccactgcagc aatgattcca gatacatcaa atgcctctgc caatacatag gctagaaaag
    34981 gaagcaaaag ttcgatcagc agataccctg tgacatcttg tgctgatgct ttttcgatca
    35041 aatgaattat tttttgtttg aaccagacaa gcaaaaagcc gatcaaagct cccccaatac
    35101 tagaaactac tagactcatc cccgcgttta ctgctgaaaa agatccggtg atcagcgcac
    35161 caagagcaaa ctggaaggca gtaacaccag atgcatcatt caaaagacct tctccttcca
    35221 aaatatgcat cgccttttta gggatattca ctcgtccaga aagagaactg actgctaccg
    35281 catctgtcgg acctaacgct gctccaaaag caaagcaggc agcaagtggg acacttggca
    35341 acaggaatga taacgtcgca cctaccccga caagggtcaa aatgactcct ccaaatgcca
    35401 agaacaaaat tgtcccgaaa tttttgagaa tcgaagaaat atctgctttt tctccttctc
    35461 taaataacaa tggtgcaata atcataacta agaacaattc aggttcaaaa tcgattgatt
    35521 gtccccactc tgtcagacct aataccactc caaggaaaat ttggatcagt ggagctggaa
    35581 tcattggcaa aatgcggcta gctatgttcg ataaggtgat cgttactgca aatacaataa
    35641 ctaactcagc aaattccatc gtccatcccc tttatttttt attttgtgta agcattttta
    35701 aaaattgttc ttttttcttt aaaattttgg tttcgactac ttcaacctgt gtttggttcc
    35761 cctctaattc acactgtaca cgttttgact ccaaacgaag cagatcatgt ttcagacgtt
    35821 ccaactgacg atacatcaat atatttcttt tacgcaactt acaaagtatt tgacggcggt
    35881 catccatcga aagggcgcca tagcgatcat gcaacagttt tttttgttgt tcaaaactct
    35941 ctctcatttt ccagatctcc tatacacaaa cttccatcat tatagcaaag ttctttttgg
    36001 atgaaaaata tttcattgtt tcatcgttta ttgctagtta gaaatttcca taaatttttc
    36061 aacgcctcat tctattccaa atagtatcag atatcaagta aaacttaaga aagataaaag
    36121 tttctgacaa aaggatgttt actttcccat tcctgccttt cttgttcttt tatcacaaca
    36181 aaaaaatggg gctgcgacaa aaatcttgtc acagtccctt attctgaata aacggtgtgg
    36241 aagagacagc ctatcagtag taataagaca catctctttc acagcctcat ttttgcgtaa
    36301 aaatcgattt attcgaaaaa ttccccgtat acatcttcta cacgttgatc tggattgatc
    36361 acgatataca agttacctgt tttttcgctg atttttgttg attgatattg attgtctaat
    36421 ccttctgttc ctttatctag atatgggaag tacacaagat caggtgtgcc atttcggtaa
    36481 aggatttcca ttcgctcgat atcttcgtat ttcaatgcgc gattaaacat gcccatttcc
    36541 agtccgccta ggttgatatc atgtgtcgca actgcgtccc cttcatggaa gatttcgatt
    36601 ttaaatccag cacacggatg gatttcaaca aattcactgc cattgattcg tccaaaactt
    36661 gttgtgattt gtttgatcca aagatcgccg atatgacggc ggttgatcgt ccaggtttct
    36721 ccatttctaa aataaaattt tagcgctgtc atttctttac tcattaaaaa gactccttta
    36781 tgatgtaatt tattcttgta ctacctcagt ttagcacaaa tttatgtaag tggtcacatc
    36841 ttatgttttt tcttctaatg acgtatctgc ccactttaag tagccaacaa agctgagcag
    36901 atacagtcta gtgtttttta aatcaatttt tctttcgata aaaaatccaa aacctgtttt
    36961 ttatcatttt ttattctttg ttctacgacg gctttttcag ctaattgcaa agcttcacta
    37021 acccacttac caggtttttt tccagtttct tctagcaaga ttttaccatc tactgctaat
    37081 tcgcttaatg acttgatagg taaacgatca taggattctc ctacggcatc catctgaggt
    37141 gtttcgtcaa aatagatcat caattcttct acttgcagtg catgtttttt gcctaagaag
    37201 tacaattcga atggttccaa agctccagtt tctcgttgtc gtagtccttg gacaagtgct
    37261 tgaacgtctt taatcatttg gttagaacac ttccacgatt tcaaaaagga acgaatctca
    37321 ttttctttta gatccagttg gctgatcaat aatgcccatg cttggctctc ttctttcaat
    37381 gggacggatg gtaattcagc aaaacgtaaa agtgcttcgc cttcttcttt caaaccggga
    37441 cagcaaatgt agcactctgt ttcaataaat gcatggattc ccgcggcccg ttcatttccc
    37501 aagagcatct tgatgaattc cacatttata cgttctacag atattttacc taatagctcg
    37561 tggttttctt tgatggcgta gaaggtttct tcctctaatt tgaaccctag ttgactgaca
    37621 aaacgcaacc cgcgcatcat tcgtaaggca tcttcatgga accgctcatg aggattgcct
    37681 acagctcgca agatctgttc ttctagatct tgcagaccat cgaacaaatc gatgatttct
    37741 ccatcttctt tcaaagcaaa cgcattgatc gtaaaatctc ttcttttcaa atcttctgcc
    37801 aacgaacgaa cgaattcgac atgatctggt ctacggtagt cctgataagt tgattccgtc
    37861 cgaaatgtgg tgatctcata ttgttcatca ttttctaata ccaacacagt tccatgttcg
    37921 atcccaatat ctatcgtttt tggaaaaagc tgtttgattt cttctggaaa tgcgcttgtt
    37981 gcgatatcca catcatggat tggctggttc agcaagatat cacgaacact tccacctaca
    38041 aaataagctt catatcctgc attctctaat tttttcagaa ctggaattgc cttttggtat
    38101 tccagaggta attgttttaa tttcattttt ccaacctttc ctgcgtgttt cttgtcctga
    38161 gataaagact cagttgcatg gtgactgttt gacaagtccg tttcagagtc ttcaaggcca
    38221 ggaccacttc atcttgttta ctcgtcctta cgctcaaagc gattatggtc tctttgattg
    38281 aatttttcca tgtttttttc aaaaacttca gttaagtcga tattcaatga attagccatg
    38341 atcatcgtaa cgaataaaac atcaccaagt tcttctgcta ccgagttaac tggttcagaa
    38401 gcctttttgc ttttttctcc ataagtgtgg ttgacttctc ttgccaattc acctacttct
    38461 tcagttaatc gagccatctg agctaatgga gagaaatacc ccaccttgaa ttgctggata
    38521 tattcatcca cttcctgctg catactgtat aaagaacgct ttttatccat ctttttccct
    38581 ccaaaactat cttaccaaaa ctttaacgca aatcctagat aagagcaatt gagaaaatcg
    38641 aatttccatg ctacatttag gaaggaattt ctaaatggaa attctgtgaa aatacataat
    38701 tgaaagctgg aattcatatg gtcaaacgaa aaacagtaaa agaagttctt tttatcatta
    38761 taggaacaag tatttatgca tttggtcttg tttacttgaa catcgctaat catttagcag
    38821 aagggggagt ctcagggatc accttgatct taagagcttt atttggtatt gatccagctt
    38881 atacgacttt attaatcaac atcccattga ttttactagg aggaaagatc ctcggtaaac
    38941 gttccttggc ctatactgtt ctaggtacac tttctttgtc attcttttta tggatctggc
    39001 aaagggttcc actagaaatc aatttacagc atgatctact gatcgtttct ctacttgcgg
    39061 gtttagttgc aggtgtagga agcgggatcg tctaccgcat gggtggaaca acaggcggca
    39121 gtgatattat cgctcggatt ttagaacaaa attacggcat cactatgggg cgttccctat
    39181 tggcatttga tatcatcgtc ttacttgctt cattaaccta tatcgacttg aaacgtatga
    39241 tgtatacgtt gattgtttcg tatgttttca gtcgtgtgat tgattcgatc ttagatggcg
    39301 gatattctgc aaaaggtcta cttgtcgtct ccaacaaaag cgaagagatt gcaccactac
    39361 tgatgaccgg tctgcaaaga ggtgtgactt tcctttctgg agaaggcgca ttctctggta
    39421 attcaaaaaa aatcatctat atggtcgtta gctctagtga attaactgaa gctaagagga
    39481 tcgtccacga gattgacgaa aaagctttcc tttcaatcat caatgtgcat gaagtggaag
    39541 ggcaaggctt tacttatttg aagccacaga caagattact gaaaaaacta taagaaaaaa
    39601 gacaaagata ggctatgagg aaagattcca catccagctg acctttgtct tttttagtac
    39661 tatactattt ttaactaatt gttatgttca cttacccggt tacttttctt ttgtgtctgc
    39721 aaaaggatct ttcggttaac ttcatcagat aatttcaaaa aagcatccct atctccatct
    39781 tctagtgctt gatcgatttg agcataaagc atttttagtt ttgcctcttc ttctttttct
    39841 tgaaaatatc gttcaattaa ttcagtatct tcttcactga ctgaagaatc ccaagaagaa
    39901 aatggattgt cttctaagat agatagatat tctcttgtct gccaagcatt ttcgaatata
    39961 cattccacat ataaaggctt tttccaattc aaacggattt catgaaaaat ctggtctgtg
    40021 tccgtaaatt cttttccctg caaaaacaat ttcatgggtt ccccttcaac agatagatca
    40081 ctgatctgca gtcctcgatc cgcaaaattc gccccttcaa caaagtggac attgcttaaa
    40141 atcgcttcat gattggcaag ataattcaag atccaaaaaa cttctcttcg gctaaaagat
    40201 acatgattga ccatccacgt taaaaaattc ttcttttccc gtacatcaat tagcattttt
    40261 ctcacctctc tgttaggtca tctaataatg acagtgcctc catatctcct ggttcaagtg
    40321 ttaaataata agtcaataat tcttgcgctc ttttcagctg cccttcttct cttaagaaaa
    40381 aggcatactc tttcaagaaa tctggttcat gtgatagttc atgataagcc tgttcatagt
    40441 gtacagctgc aacggtaaag tcttctaatt cattataagc atgggctagg ttccattctg
    40501 cataaggatt agcagtttct tccatctgat tgatcacttg tatcacatct tcatatcttt
    40561 catcatccaa gtaaagatta cttaaagtaa gtaatgtttc atcttgtttg tctcctactt
    40621 ctaaagcttt cagtaaaagt tcttctgctc gctgtctatc atgcagacgg aaagcatttt
    40681 ccgaggccag gtgataaagt tcgacttggt aaggattttc tttgattcct tcttctaaca
    40741 ctgtttgtgc ttcttcaatc atttcttctt cttgaagagc ttgtcctaga tatagatata
    40801 acgattgata atgcggatta acttctcgaa gttcttccag atagttgatt gcctgctgat
    40861 tttctttcaa ttgaagattc gtaaaagcta gctggaacag tcgatcatct gtcctttctt
    40921 ctttcagtgc ttcttctaaa ggtacgatag ctgcttcgaa ttctccttgc atacttaagg
    40981 attgtcctaa acgttcctgc atcgagattc ctgaaatttc atttatcccg cttgccaaca
    41041 atgtttcata aaccactgct gcctctttga aacgatcaac tgaaaaatac aattcagcta
    41101 gcgcaaactg gatcaatggt tcatcaggaa gcaacccagc tgcttctttc aattttgctt
    41161 cactcacttc agggattccg ataacttggt acaaatcagc tatcgccaat aagctttgcg
    41221 gatagtaatc actttgctta tccacttttt ccaggtattc aaaagctaag tcgatctcat
    41281 tatcttcgat tgcaatttct gctaacggga tgttcagtcc gtcattttct gggtattggt
    41341 tgatcagttg ttcaaaaatc tgttttgctt cgatcaaaaa gccaatagcc agcaattctt
    41401 cgcctagttc agctaatata tctgctgggt cttcttttaa tgctttttct aaaaagattt
    41461 gtgcttgtga caagtcttca tctgataaag cttgcaacat tttttcgcta tttgtattca
    41521 tttcaattcc ctcttatctc actgacgatt tgttgaaata ccgtcattgt tctcaataat
    41581 tctttttcgt ttggatgttg gtatccgtct attataccta ttttttctaa aacaagtatt
    41641 tttttgcttt tttctgccaa aaaaagaact ttttccaaat actccatctt tgaaatctgt
    41701 tccagccagt ggattggata gccaagcaag tccagccaca caaaaaagtt ttttagttgg
    41761 aaatcaaaag gatatgcttg gagattccac acgaaatgaa acatcattcc taaaaatttt
    41821 ttcatactag cagaaagtag atggccattt tcggtcagat aaaaagcttg ttcaaacagt
    41881 ttaccataat ttgacaggtt ttctgcctct aattgataaa aatagatcat ttcttcgatc
    41941 atcccggcaa acggccgagt cgttaattgc tttttatttg gatagttttt atacagattt
    42001 tgcaaaaaac gatgatcaca aatcattccg caacagataa aagtcaaaaa gtcaatctgc
    42061 tttccgtcca cctgccgctc gctgattgtt tgatcataaa cgatgcgttc tggcagattg
    42121 atggtttgca gcactacacg atttggtagc tgcaaaatcg tccgctgcgg tgttaatgct
    42181 cggcttagag aacggatcga tacagggatc atccatagtg atgaatcaag ggttgtatgt
    42241 ttttgaaaaa aacctgccag atccatgatc ccttcatttc caaatccgat gataaacatg
    42301 gattgatttt cgggatagcg tttgacgaaa tcaagcaggt tctttaattc tgttaaatga
    42361 ttgcattgag tgttggcaca aatataccag tcattgtttg cttgatttgc aaataacggg
    42421 ttgatcttat ctgcaaacaa atcataatag cgctgattcg ttaaaaataa gattggctga
    42481 tcaatggaaa gttctcttag ctgactgact agcgtttctc cgtaaaacac tttcgtcaac
    42541 gcatcttcta cttgataatc aagttccata cgcatccctc ctcttcttat ttttatttta
    42601 ccattagtaa gcaaattcta gaaaagataa gagcaaagct cacctcataa cttgcaaata
    42661 aataaaaatt aaataaaata catgtgtttt ctatgtatga catacggatt cggaatctct
    42721 gtctcttatt tattcctttt ctgctaggaa ataaaaagaa aagcacttgt agccctagag
    42781 ccacaagcgc tttttcaact gtcttattta acagcgtctt ttaatgcttt acctggtttg
    42841 aatgcaggta ctttgctagc tggaatttcg atttcttcac cagtttgtgg gttacgacct
    42901 ttgcgagctg cgcgttcgcg aacttcaaag ttaccaaaac cgattaattg aactttttcg
    42961 ccgttagcta aagcatcttg aatagttgaa aatacagcat ctactgctgc agttgcatct
    43021 tttttagtta aatcagtagc tgaagcaact ttttcgatta attctgcttt gtttgccatg
    43081 gatagattca cctcctccac aagagatatg atagaaatat catttagtta aaactttctg
    43141 agtggtccag aagtttaaaa agaaatattg attaacttca atattctgtt atcacgatat
    43201 catatgaacc gcttaatagc aaggttttta ccaattttca catgcttttt ttagtcatag
    43261 aaacgtaaca aacgaaactg tctttttctt ttgaaaaaaa aacgtcgata tggtaaaatg
    43321 cctattttct cctacgaggg ataattcgga tggacgtccc ttcaaaagta aatgcttttc
    43381 tgatttgatt ttctaagaaa cgttcataag aaaaatgcat caattcctct tcattgacaa
    43441 aaacgacaaa tgtaggtggt ttgacagcga cttgtgtagc ataaaaaatc ttcaggcgtt
    43501 ttcctttatc tgttggtgtt ggattgattg ctacagcatc cataatgata tcattcaaca
    43561 cagccgaaga gatacgaaga ttctggttca tacttacttg ttcgatcatt tcaggcagac
    43621 gttccaaccg ttgtttagtc actgcagaaa caaaaacgat tggagcgtaa tcaagatacc
    43681 ggaattcatc acgaatctct tgttcgaaat cacgcattgt attggtttct ttctttacaa
    43741 gatcccattt attcacgacg ataataattc cacgaccagc ttcatgggcg taacccgcta
    43801 ctcgcttgtc ttgttcccga atcccttctt cagcattcag taccatcaaa acgatatcag
    43861 aacggtcaat ggcacgcatt gcacgcatca cgctgtattt ttcagtattt tcgtatactt
    43921 ttccgcgttt acgcatacca gctgtatcta tcattaagaa tttctgacca ctttcagaaa
    43981 cgaagtgggt gtcgattgcg tctcgggtcg ttccttcaat atccgaaaca attacacgtt
    44041 cttctcctaa aatcgcattg atcaaagagg atttaccaac atttgggcga ccaatcaaac
    44101 taaacttaat cgtgtcgtcg tcctcttctt cagtctcttc agagaaatac ttcactgctt
    44161 catctaaaat atcaccaatc cctagtccat ggcttcctga aacaggataa ggatcgccta
    44221 gccctaagga ataaaattca tagatatcgt ttctcatttc tggattatct actttattga
    44281 ctgctaaaat cactggttta ttacttctgt ataaaatttt cgcaaccatc tcatctgcgt
    44341 ctgtcacgcc ttcgcgtccg ctgactacac aaatgattac atctgcttct tcaatcgcga
    44401 tttctgcttg atgcttgatc tgatccataa aaggttcatc gccaagatca attccgcctg
    44461 tgtcgatcac gctgaattct cgacctaacc attcaccttt tgcataaata cgatcacgag
    44521 ttactccagg agtatcttcg acaatcgaga tacgctcacc agcgatgcgg ttaaaaatcg
    44581 tagacttacc gacgttcggg cggccaacga ttgcaattgt tggatttgcc atattatttc
    44641 ctcctcacaa gtttccaatc tcacttagtt taacgaatgc attgccaact ttcaagcata
    44701 gattgtcaat taaacgaagt atttttattc cttattgaaa tactaatcgc ttttcaaaag
    44761 aaaaactgag acaaaagcag ctgctttcat ctcagtcaca gatacaaaat caattatttt
    44821 tcagaatcat cggttgcttt ttcttctact tcttctttca acgcatcacc taaaatgtct
    44881 cccatagtaa atccagtatt ttcttctggt aattcataag actcaacatt ttttggttct
    44941 tcttctgaag ctggtttttc ttctaaagct ttgatactca atgcaatacg atgttcttct
    45001 ggatggatct ctaatacttt cactttcact tcgtcacctt catgaagcac ttcatgtggt
    45061 gtcgcaatat gtttatgtga aatttgagag atatggacta gcccttctac tccagggaac
    45121 acttcaacaa aggcaccgaa gcttgtcaaa cgtttaactg ttccgtctaa tactgtgcca
    45181 actggagctt ttgtatcgat ttctgaccaa ggtccaggct gtgtgtcttt gattgacaag
    45241 gaaacacgtt cttgttcagg attgatagac aacactttga catttacatc atcattgaca
    45301 gccaatacat cacttggttt tgctacatga ctatgtgaaa tctctgagac atggactaga
    45361 ccgtcaattc cgcctaggtc gacaaatgcg ccaaaatcag taagacgtgc aacacgtcca
    45421 ctgagaacat ctccctcatg gatagttgaa agaatttctt ttttcttttc ttctctttcg
    45481 ttttccacta ccgctttatg cgataagatc aaacgatttt ctgatggttc gatttcgatg
    45541 attttaaagc tcaatgtttt gcctttatag tctgaaaagt ctgcaacaaa atgatcttcc
    45601 accattgatg cagggacaaa accacgtaca ccgacgtcaa cgactaaacc gcctttgaca
    45661 acatttgtaa caggtgcttc gatgaccttg ccctcttgga aatctctttc gatatcttcc
    45721 caaacttttt tagcatctaa acggcgtttt gaaagtagat agctgccgtt ttctttatct
    45781 ttgccgatcg tactgataac gactaaatct aatacatcac cgacttttac tacttcgctg
    45841 atatcttcta ccggcaaagt tgataattct tttgccggaa cgactccttc aactccagcc
    45901 ccttcgattc cgacaatcac ttgtttgtct tcaatgacta aaacttcgcc cttaacaaca
    45961 tcgccaactt ttacttcttg tacgcttttc attgcgtctt ccattgactg gttgttctct
    46021 tgattttgat caaattctgt cataacactt gtcctcctaa ccaacattct gccgtaagta
    46081 cggtactgtt tttagtttaa ttgattattc aaaaaaaata aagcgatttc gttcgttttc
    46141 cttgaaaaaa caattgtttt tcattttttt tcttaattta aaaaagaaga taaccttttt
    46201 tcaaaacaac agcttttatt gctgcaacga cttctggaat cgatttgcca gtcgtatcga
    46261 tacgaacagc atcctctgct tgcttcagcg gagagacgtc ccttgttgaa tcataatggt
    46321 ctctttcctg tatctctttc gtcagtgttt caagatcagt cggaattcct ttttcttggt
    46381 tctctttgaa acgtctttct gcacgctcac ttacgcttgc tactaaaaag attttcactt
    46441 ctgcattcgg taatacagct gtcccgatgt ctcttccgtc catgacaacg ccaccgcgtt
    46501 cccctatttt tcgttggaca gcaactaatt cttctctgac ttttccatgt gcagagactt
    46561 cagaaacagc ttttgtgaca tctggttgac ggatttctaa agtcacatct tttgatgcta
    46621 tgaatacatg ctgtccatct tcttgttgcg aaaaagagat aggatacttt ttgatcagcg
    46681 aaactagccc ttcttcatct gaaaaagata cattgttcgt aatagctaaa taagttactg
    46741 cgcgatacat ggcaccggta tctgtataaa tataattcaa ttcttttgct aatatcttgg
    46801 caacggtact tttcccagat gaagcaggcc cgtcgattgc aatactgatt tgtgtcatga
    46861 tataactcct ttttctcaga aaaaaagccg caaagcgcgg ctattattat ttaattctta
    46921 attcttgacc agggtaaagc ataaagttgt ttggatctaa gccattcaat tcaaacaatt
    46981 gatcagtggt gatccctgca cgctcagcca cttgttttgg accttcgcct gcttgaacag
    47041 tcgttgttga accggctgca gctgatgaag aaggtgttgt ttctgctgca ttgctgcttg
    47101 aatcccctgc ttgataagtt gcctcacttg aggaagtcgg tgttgtctct gctgcaatac
    47161 tgctttctga cgttacacct gtatcttgag acacagtaga ttcttccgcg attgtactag
    47221 attctactgt tgaagtctca gttgactcct cttttgttgt acttgtagaa ctttctacta
    47281 ctgatgtcga agtttcagaa gaagttgctg ctgttgcatt gttgcttgat ccatttctga
    47341 tccagaaata agcacctgct ggaatagcga tacataagac cagtaaaatc aaaaatagcg
    47401 aaagaaataa tgtatttcct ttcttttgtt gtctctgaga acttcttgat gaaacttcat
    47461 catctgtatc gtagattggt tgttcccatg gttcttgtgt ttcgttattt tctgtagatt
    47521 gatgtctatc ttttctgctc actgttttac ctcctaaact ctatcgtgtg tattatacca
    47581 taggaaaaag tgtcttgtcc taaaaaatca atgttccatg ttttttttaa ataaatttag
    47641 taaaatcgtt ccccaatgaa gttgttcagt cttagaaaaa agcttcctct ttggcagaag
    47701 ttctgctttt gctccatcaa tatcacaaca attctgcggc ttttcggaga gtttttcgcc
    47761 aaaataagct aagatgaatt ttctgcggca gttttcttca ttaatatagc gaagcatctg
    47821 ctgcaggcgg aattcttttt ctttttcctg acgtttgagc cgttccaccc aattttctgg
    47881 tttttcagac tgctggatca gctccatcca ttttttttgc agctcatcaa agggagcttg
    47941 ctctgtggca tattccaaat aaagctcaaa actttgtcgc tgttctctag aaagttgatt
    48001 aaagaaataa tggatacgtt catccccact ttgataaaaa agaattgctg cactttcttc
    48061 ctgatctctg cctgctcgac cgatttcttg tacatagttt tctagactgt ctggcaaatc
    48121 ataatggacc acataacgga tatcagattt atcgatcccc ataccaaatg cattcgtagc
    48181 aatgagaaac tgcagctgat tttttacaaa ctgctgttga agttgtcttc tttgagctgc
    48241 atcaagacca ccgtgatagt atccaactgt aaaacgttcc ctgaataaat gatacaatcg
    48301 ttcgacttct ttttttgttg cacaataaat gattgccgct ccttgtgctc tttccatgaa
    48361 gtgttcaagt tcttgttctt tttgctgcgt tttccgaaca aaaagcgaga tattttgccg
    48421 attgactgat tgtctgatct cttttggtgg tcgatcaaat agtacatgac gtatatctct
    48481 tgctactaaa tctgttgctg tcgccgttag tgccagtgtg accgggtttc ctaaaagctt
    48541 tcggattttt cctaactgtt gatattctgg acggaaatca actccccatt gagacacgca
    48601 atgagcctca tctactacat ataacgcaat attttgtttt ttcagatgct ctaaaagaga
    48661 aggattagtc aacatttcgg gactcaaaaa caaaaattta tattgcgata gatgacggag
    48721 gacgtatctt ctttcagatt gcgaaagtaa actattgaaa gcagctactc gtttctcccc
    48781 tcgtttttgt aattgcgtca cttgatcttc cattagagaa agcagcggtg acacgatgat
    48841 gaccagacct tccattaaat accccgtcaa ttgatagcaa aggctttttc ccgttcctgt
    48901 aggcaaaata gcgagagtat cttctccatc aagcaacgcc tgaataattt cttcttggcc
    48961 gggacgaaat gaatcaaatc caaaatattt ttttaattca tttattaaca ttctgtatcg
    49021 cttcctttct caatagatag atttgataca aacgaaattc tccataatct aattgtccat
    49081 ctacattcca ttcgctaaag cgccactctc gcacggaatc cttatttggt tccaaacgtt
    49141 cgattgtttc tgcagagaga atccactcgt atggaaaatc atcaaaaaac aaggcccact
    49201 caataagatg atctgttact gttcctcttt ttaaatgacg gattgccatg atctggtcaa
    49261 ttgtctgacc attcataaac atctgcttgg tgatcatcat gctttgattg aaattttgct
    49321 gtaataatga atcgatcaaa gcgtgccaaa gcgaatctgg ccgtttttcg atttgtgcta
    49381 acaaaaggtg gatacatctg ctttgttgca gataaaccgc tgactcatca ttgttttttg
    49441 ccagctgata aggaagcagc cctgttcgct catttccaga taattggtta gctaaaaaat
    49501 ctgctgcttc ttctggtatc tccgaaaaca gctgcaccaa actctcatac gcagtatcaa
    49561 tcaaaatttc acgtggcaat tggctttcac taagccattt ttttagttgg aaagtataaa
    49621 aaggacttgt ctctgctgga agatagtctt gaatacccgt tgccagatta gaaattactt
    49681 gaacagcaaa tttaatgagc cgccaactag tttcccctgt tctgccatag cggtcaaaac
    49741 gcaaaccagt atgttctatt tgatgttcgg acaacatatc agcccctgca ggcgttagct
    49801 ttgcttcatt ttcatttatt tcgatccaac cttgctgcgc aattttttgc aaaatttgat
    49861 aaaacttatc ctgcttcaat tctggaaaac tgttatggat aaacaaaagt tcgtgggtaa
    49921 atccataaat aagtactgaa gtcgttcgtt ttcccacaag gagttggtaa agagaactaa
    49981 tccgcagctt gtgtcctgat gaaaatagcg ataaaataaa aacaatcata ttattctcct
    50041 taagttagga tggttagaaa tgtcactact atgtaaactt gtacctgaac gctgtattgc
    50101 atgcggtctt tgtcaaatcg aagcgccaga tattttcgat tatgatgaag aaggaatcgt
    50161 tttatttgcc caagaaccag aggctcatca acagttcgtg atgccggaag aagaaacata
    50221 tgtaaaaaaa gcgtatcaaa aatgtccagt tcgagcgatt ttattagaaa ataaaatata
    50281 aatataaacg aaactttaaa aacgtacact aagttctcta aacttgaaaa taagccggga
    50341 tctgtttctc ttgttccgtg aaatcccgac ttattttgaa agattcattt gctatctata
    50401 gttaattgac tagttttttc acggacccta taggacccat ttatattatt tcaacttttt
    50461 cagccagttt tccaatgtat tgacgatcac agtttgctgg tctgcgttag aaatttctgc
    50521 ctctccatct cctttttgct caccatagct gccaaaacct ccatgatttc cgccattgat
    50581 tgatacatac tctgttcttt ccggtaaata ctgcttagct tcttgataag cttcctgatt
    50641 caatacttta tcttttgtcg ccgtgatcga taaaacagga acagctgatt ctgtcaatgt
    50701 tccttttttg tcgggataac ttgccatgaa gaatacccct tttaaatgtt tgtctgaatg
    50761 attcttattg acataacgac ttgccattac gccacctaat gaatggccac cgatcacata
    50821 atcggaattt ggaaaatctt ctttgacctt atccgctttg tttccgccca tcactgctag
    50881 atcaagtggc attttgacaa tagcgactga aaagccgttt tttgctaaat cttgcgccca
    50941 aatactataa ctttctggct ctacgagagc accaggataa aaaataagta atggagactt
    51001 tccatgattc tttttctctc cttcaaaaaa taagtaatct tctttgtttt ttccttcttt
    51061 taccaacact tgcgcttctg acgatggttc gtacgtattt tgctgtatat agtaataacc
    51121 ggctccaccg agtaatccta aaatgatgac taagccaatt agtattcgtc taaatatttt
    51181 cactttctcc caccttttct atctgagtga cccctttttc ttaatcaagt atgattatac
    51241 cttaaaaaaa taagagagaa atgcaaactt tccagcatca aataaaaaaa gacggaatat
    51301 ccatttgaat atccgccctt tttgtatgtt tatttttatt tagcacataa acgatacaca
    51361 gcttctgcat aaatttccat tgctttatac atactactta attcccatcg ttcattcgcc
    51421 tggtgcataa agtcaggagt atcagggaac atcgcaccga atgccacaca ctggttcatc
    51481 gtacgagcaa aagtagcgcc gcctgataca aacggttcag tcatgtctcc agtaatatcg
    51541 cgatatgtcc ccaatagatt tttcactaac tcactgtcta gtggcacgta taatgaatca
    51601 aggaagtcaa attcttcata agtcaaccca tatttttctg ctgttttagt taatttagct
    51661 actaaatcat ctttcttgaa tgtaacaggg attctcatat ctacaccgat ttttgtttgt
    51721 tctggtgtga tttccaaact tgcaaagttc atcgttagct cgccggattg ttcatcttct
    51781 gttttgccca cgacagcttc accagttgca ttttcttgaa ctaattttcc taagaaattg
    51841 attgggccaa aatcaaatac ttctgaaaga gcaattgcca gacgagaaat agcattcact
    51901 ccttgtgctg catctttcgc gtggatactt ttaccaagaa cgacgatgcc ttcaccttgt
    51961 tcttcgaaat cgaattcgtg ttttttcaat gcttctttta cttcagaaag cttttctcca
    52021 gagtaaggag ctgcatcagg aacaacattc aacgctcctc cagcttttac agaaaactcg
    52081 ttcgttcctg gtcctgtcaa gtaagcttgc aataagcctt tttctgcata aattaaagga
    52141 aattcagcat ctggcgcaaa tccttgcgta attccttctt ctttttcgtt atatttttct
    52201 aaacaacgcc ataaattttc ttcatctgta ccaaagataa aacgaatacg tgtcttgaat
    52261 tccacgccag catcaatcaa agctttgacg gcatacattg ccgcaataga aggacctttg
    52321 tcatcttggg atccgcgacc aactaaccag ccgtctttta tagttggatc gaatggtttt
    52381 gtttcccaat tattttcgtc ccctgctgga acaacgtcca tatgacacaa gataccgaat
    52441 aattcatctc cagagccaat ctctgaataa ccgtaatagc cttctggatc tttaaatgtt
    52501 ctaaatccta gcttttcact gatttccaat actttatcca aagcttcaat cactttttta
    52561 ccgaagggat gtccttgtcc tgaatctgct tcatctagta cggaaggaat tcggatcaat
    52621 tcgctcaatg attctaatgc ttgttcatga tgttgttctg tcacaaattt tttcatgata
    52681 ttatcctcct aatatgttaa aaagggtcat gtcaaattcc tccgacacaa cctcttcttc
    52741 tcaaataatg acgttttaag cctgctccat cagcaagcag aatgttctta acaaatgatg
    52801 aaagaaaaaa cactcactga atggagctat tgacttatcc acgtgcttat cgatagccgt
    52861 ttatcggttt cttcattctt atgatagacc ttgtacctgt atttgtctag gtttagaaca
    52921 ttgctgctac acctaggatc acacagatgg ctacaaataa tatcgcaatt aatttaccgg
    52981 taaatttcca ccacactgaa acatcgaaac gagcaattgc tacagcaccc attacgatag
    53041 cagatgttgg tgtaattaag tttactaaac cagatgcaga ttgataagca gtgattacta
    53101 aatccttacc gacgccggca aattcaccca taggtcccat gattcccatt gttgcagcag
    53161 ctaagccgga agttgaagga atcaagaatg acatagggat atagaaaata aatgtaataa
    53221 tgatgaatac acttgaagat aatgaactta atccttgttc gccccaatgt aagatggtgt
    53281 ctgtgattaa tccattgttc ataaccactt ggataccacg agcaacagct actacgattg
    53341 ctacaccgat caaatcagaa gcaccagcta aaaattcaga gacaaattca gactctttca
    53401 tgccataagt gattgctact acgatggaca ttactaagaa taacatagta atttctggga
    53461 agtaccagtc acctaatgga agcatgcttt tacctagaac cgtacctagt accggaaggt
    53521 ttgttaacca gtttgtcaat gattcaaaaa tcgtgaaatt cgcattcaag gttgtccaag
    53581 gaatcaaact gatgatcatg ataccaaaag taataaagaa caatacatta acatgttttt
    53641 gttttttcgt gattacttct tgacgaccga ttgcttcaat atcgaaatgc ttcatatctt
    53701 ctttacgttg gttgtatact aatgattttg ttggatcttt ttcgatcttt gatgcataac
    53761 gatacacata tacaatagaa atagctaaca aaataacgaa catcaagaat cgaagaccaa
    53821 taccttcacc catcgaaatc ccaacagctt gtgaagctac gcctgttgca aaaggattta
    53881 ccgttgaagc tagacagcct acttgagacc ctactaatac gattgctaca gctactactg
    53941 tatcaaagcc tacagccatc atgactggga tcagtaaagc atagaatgga atcgtttctt
    54001 ctgccattcc gtaagtagag ccgcctaatg caaataacag catcaatact ggaataagca
    54061 ttttttcttt tcctttgaat ttcttcacaa ctgaagcaat cccggcatct agtgcccctg
    54121 ttttgttgat aatacctaaa aatccaccaa caaccaaaat gaagaaagag attgggattg
    54181 cagcaggtgt ttctttagtt agctcccccg ctggtacacc tagcatccca ttgattggcg
    54241 ccatgaaaat atcccacagc ccttgaggat tttgttgtac tcgttcatat gatccagcga
    54301 cgatgttgcc tgcatcgtct acactatagt gcccagctgg tataaaccaa gtaagtacag
    54361 cgattactgc aataataata aataagaccg tatacgctga aggcatttga aattttttct
    54421 tttttgtttg ttccatcttc ttcttccttt cttttccgtt agagacaaca attttggctc
    54481 taatgttatt ttatcaaaaa gagtatcaga acaaaaataa taacacgcat tttgtaaaac
    54541 ttttgttcaa aaagttcgtt tttccctatt ccctcctctt ttttcaggtt tttaaagctt
    54601 tcttcttttt cattgtagcg tttccttttt tttataaaca aacattttcg tcttttaaaa
    54661 ggagaagaat ttcacatttg caaagaattg attgattttt atgcataaat caaaaaaata
    54721 ctcaaaacaa acaaataaaa cgtttacatt attgcatgtc ttgtattttt ttccaaaaaa
    54781 aaagaccaag aaatttcttg atctttttga tatttatttg actgctgtat gacgttgttc
    54841 gaactgatgt tgttttcgac ttaaccatgg aagaagttgc gcatgcagca ctaaaaagac
    54901 agcactcacg atgaatcctt tgatcaagtt gaaaggaacg atcccaatca gtacatagtt
    54961 tgctaaagac atgcccagca tctgtgttgc gttcagccct aaaaacatta agtaaagagg
    55021 cgtaataacg aaataatttg cgatactcat aaaaatagtt agagcgatgg ttcctgtaat
    55081 gacacctaaa aatttgtttc ttcctttatg ctgtttcttt acactaaaga aataataaat
    55141 cgggaatgta aagatcgttg ttgataagaa actagcagtg tctcctacca aattatccgg
    55201 agaaaaacct gtagtcagca gatgtaatac tgaacgcaag aacgctgttg caactccggc
    55261 cgctggaccg aataagaaca tgctgatcaa taccgagata tcactaaaat cgatcttcaa
    55321 aaaactaaaa gccggcatga tcggaaaagc aaaatactgt aaaactaatg cgatcgcagc
    55381 aaacatcgct actgcaacca ttttctgtac acgggtgttc ttcatttgaa atcctcctgt
    55441 taggactcct cttcagcgaa ctttttgacg tttctctcca aatgaaaaaa ctctattttc
    55501 cagggaaaat agagttagag ttatttgatc aagcgtcgtc aaataagctc tatcttcttt
    55561 atccagacta tactgtcggt atcggaattt caccgattca gctatttttt tgcaaaatag
    55621 gtcgtggact ataaccaccg gtcgggaatt tcaccctgcc cctgaagacg aaccttatat
    55681 aatttttgtt tacatattca ttatacatat ctattcaaaa aacgcaacat ctaacactta
    55741 taaaaagtaa gtgttcattt tgagtggttc agcaaactgc tgacttcttt tttgttcagt
    55801 tcacggtaat ccccaggacg taggccttgt aaagtcagat ctccgtattt ttcacgtttt
    55861 agtttttgca caggaagacc aactgcttga agcatatttt tcacttgatg attacgtcct
    55921 tcgtggatcg tcaattccac gatactgtgg tttgtcttag gatccactga taaaatttgg
    55981 aatttagctg gagatgtttt tcgtccttcg atctttattc cttttgtcaa aggtgcaagc
    56041 atcgattttg tagcgatccc ttttaccttt gcaacgtaaa ctttatccac ttcatgtttt
    56101 ggatgtgtca ggcgctgagc aaaatctcca tcatttgtca gtagcaagat ccccgaagta
    56161 tcgtaatcca gtcgacctac aggatagata cgttctttta ccatcggcaa aagatccgta
    56221 acaacttttc ttcctttgtc atctgcaaca gcagaaataa ctcctttagg tttgtacaat
    56281 aaatagtaac cgtattcttc ttgataaatt gggacttcat ccacttccac agtgtcatgt
    56341 ttcccaactt ttatccctaa ttcccttaca acttgtccgt ttacttttac acgtcctgca
    56401 aggatgaatt cttctgcttt tcgacgagaa gtgatgccag cgtgggcaat tactttctgc
    56461 aatctctcca ttacaattat tctcctttat tcattccatc aaagaataga tctggtgaca
    56521 cgtcttcttc aagtgaaatt tccatttctt gtgtatcagg cagttcttct aatgatttca
    56581 aaccaaaata atctaagaag tagccagttg ttccatataa tatcggccga cctggtcctt
    56641 ctactctacc tttttcttca atcagtttat gggcagctag acgctgtacc gctcctgaaa
    56701 cctgaactcc tcgaatctgc tcgatttcag ctcttgtgat tggctgttta taagcgatga
    56761 ttgctaaggt ttcgacggcg gcttgagata atgtgtttga tgtcccttgc gcatatcgct
    56821 taagtaaggg agccagctct tttttagtcg ttaatacata atggctttcc gtttcaaaaa
    56881 tatgcaaagc tgagtgcgag ttttgagtgt aagattcttt taattctttc actaaacttg
    56941 tgacttctgc ttcgctgaga tttaacagtc cgcttaattc ttcattactg atcccttcct
    57001 cgccaacaat aaaaagaagg gcttcaagtt cacttaattt cgtcatgttc ggtatctcct
    57061 actgctggat aaagcataat tgattcatag ttttcttttt gttgcgcaat gatctgccct
    57121 tttttcatca attctagcaa agccataaaa gtagtgacaa cttcactttt agaaggtgac
    57181 tcaaaaaaag aatcgaaagt acagccatgc gcatttcttt ttatacgctc ttcgataaat
    57241 accattcgtt cttcgatcgt tgtgtcatcg ggcgtgatcg ttttttccac tttttgagaa
    57301 aatttcttac gttctaagat tttctgcatg gcacggatca aatcgatttt tttgacttgt
    57361 cctcgcttca acggcttttc agcatccgct aacccatcga tgttcatagg ttcttttgtg
    57421 taataaagac ttcgttcctc tgctttttct gtcagtcttt cagctgcata tttatattta
    57481 cggtattcta aaagctgagt gaccaattct tctcgaggat cttcttccca taattcttca
    57541 tcgtctgtga cgaattcttg gacaggaagc aatgtcttgc ttttgattgc catcaatgta
    57601 gcagccatca ctaagtattc tcctgcaaca gctagctcga gtgttttcat tgtatggata
    57661 taattcatat attgctccgt gatcgtagcg atcggtatat catatatatc gatttccatt
    57721 tgctgaatca gatgaagcag cagatcgaga ggaccctcga atacatctaa tttaatattg
    57781 atctccgtca actcattcac tctttcttct ttttctttgc tagccatttt ccaatgtaag
    57841 gctctgtgat ttcagttgca cggatggaga catccgggta cttttcctgt aattcatcta
    57901 acatttgaaa gcccatattc tcaccgcgat aagacggatt caaagaaatg tcatggatga
    57961 tcagctgatc gttcgttgcc cagtaaatac caataatccc ttgaatgttg gttgaacctt
    58021 ctggcgtaaa gaaaaaaagt tcataatcgt cttcagattc gtacgtatca atctccttca
    58081 acaaagaagt tttacctgtc agtttcttat ggaaactcaa tagtcccata gcaattttac
    58141 ggttttcttt ccggtaatgt gttaacatct tctcaccttc ctatgactaa gcccttggaa
    58201 aatgctgctt ataaacatcc gtcattcttt tcttcgtgat atgtgtataa atctgagtcg
    58261 tagagatatc cgcgtgacct aacaattcct gtactgtccg caaatcagct ccattttcta
    58321 gcagatgtgt ggcaaagcta tgccgcagcg tatgtggtgt tacttctttg taaatcccag
    58381 cctctcgtac taactgcttc agatttttcc agattccttg ccgagaaaga cctttcccat
    58441 gattattgac aaatacatgc atttcagatg cgtcctttac aagtaatgga cgtgcttcgt
    58501 ctaagtagcg ttccagccat tggatcgcat aatcacctaa aggaatgatc cgctctttat
    58561 ctccttttcc aactgtctgt accagtccaa gagaaagatg aagatctccc aatttcaatc
    58621 caatcaattc actgacgcgc atcccagtag catacatgac ttccaagatt gcacgatctc
    58681 ttatccctaa cgtttttgtc gtatcaggtg cttcaatcag cttttctact tctgtcagag
    58741 tcaatgtact tggtaatttc tgtgctttct tcggcgtatc gatatgttgc atcggatcat
    58801 gatcagtgat acgctcttgc cgtaaaaact gatggaatct tctgagactt gagatcatcc
    58861 gagtaacagt tgctgtcgct tttttttctt catgcaactt ctccagaaaa cggatgacta
    58921 aaaagcgatc gacatcctgc catgaagcaa ttttctgctc ctgtagaaaa tgcaagtact
    58981 gttccaaatc acgttcatag ctttgtcgtg tattggcgga caatccccgt tcaatattca
    59041 agtagtggag ataatcgttg atttgctctt tcataataat ccccctcatg cctctctatc
    59101 atatcagata ccgcttcatt ctgatagtct ttttccataa tctgagcaaa gaaaaa
//
LOCUS       DAZKKZ010000008        59026 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.008, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000008 DAZKKZ010000000
VERSION     DAZKKZ010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 59026)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 59026)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..59026
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.008"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(159..1469)
                     /locus_tag="ACG8LA_000550"
     CDS             complement(159..1469)
                     /locus_tag="ACG8LA_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004650 - polygalacturonase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 28 protein"
                     /protein_id="HFQ0202880.1"
                     /translation="MRTKKGIINALNFKTNDTQQDDTIILQKAIDQGAKEHLPVFIPK
                     GIYLVGALFLKDKSHLIFEEGAVLKGRTDIEAFPEIDTRVAGVEMKWPAAILNVLSAK
                     DILIEGKGIIDGQGDHWWELYWGKDQKSGTRAEYDQKGLRWIADYAIKRPRACLLYHA
                     EHVVVRDLIFQKSGFWNLQITYSNDVLVEKVIIRNNDGPSTDGIDIDSSTNVRVYECD
                     LACGDDCIAIKSGRDGNGARVNRKSSRIEVARCKIRSGYGVTIGSEVSAGVSDVYIHD
                     IDFFQSDCGIRMKSSKERGGVIENIRVENLNMIDVQFPFSWIMDWHNEYNRKNSNDLA
                     QMPESWQAVAEEIPESKQMTKVKDIHIKNVQACLSPGYSLPSRAFDLVAFPEKPIEDV
                     CFSHCQITAKEFGRIEAVQNLCFKSCDLSIETGNTAANNTFDNR"
     gene            complement(1481..2899)
                     /locus_tag="ACG8LA_000551"
     CDS             complement(1481..2899)
                     /locus_tag="ACG8LA_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFQ0202881.1"
                     /translation="MLSQNAVTANTIKKEKKEFGISDKIGYMFGDLGNCFILGLVNSF
                     LMIYYTNVLGVSGAIVGTLFLISRILDAFADVMVGRLCDVSELTETGRFIPWIRKMKY
                     PFCLVTVILFLPFVQHLPMTVKIAYIFVSYIVYGIFLSTINIPYGAMAAAISSNPNDR
                     TSLSTFRSIGSAIGGSTTGFFIPILMYTHNKSGQQVVSGNHFFWISIGCAAIAFVAYM
                     LTCKLTTERVRVVKNEKVSASQLVKGLLANRALIILVIVDIFIVINQILAGTNMTYLF
                     NDYFHNKQAMSVALLFTYGTVVVLAPFATKLTKLFGKKEASVFALLASSCMYLLMYFL
                     HITNAWVYLILLFIATLGSGLFNLMVWAFITDVIDYHQYKTGLREDGTVYGVNSFARK
                     VGQACAGAVGGFMLALIGYQSSTTGGAIQSVLVQERIYTMANLLPAFCLFVSAIILLV
                     GYPLNRSKTVFIGEELKKINER"
     gene            complement(3139..4707)
                     /locus_tag="ACG8LA_000552"
     CDS             complement(3139..4707)
                     /locus_tag="ACG8LA_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HFQ0202882.1"
                     /translation="MQTIKVKNPILRGFNPDPNILRVKERYYIIVSSFEWLPGIRVYE
                     SKNLVNWSHTTDILTTQVSLQGNPTNGSIWAPQISYADGLFYLVYTDVKSAGRPFKDV
                     HNYLITASEITGPWSEPIYLNSNGFDPSLFHDLETGKKWLVNELWDYRLDTPNKSSGI
                     VLQEYDAEKKKLDGPIYKIFAGTELAKTEAPHLYFRNGYYYLMTAEGGTGRGHSVTVC
                     RAKNITGPYELDPGFPMLTASDKPASTLQCTGHGSLVQTPSGRWYMTYLCTRPLNGAA
                     ILGRETAIQEVYWTSDDWLRLKDSQTTPMEEIMIETNEEVQQEKDHQFMDTFEGELKK
                     NWNARRILPNADWCDTKCRPGFLRLISGESLQSTFEHHLLAIRQTDFTFDAETAFEYM
                     PNNFNQMAGLVLYLNESNYIYCYVTWNEDKGKCLRMIESENGVAQIEDWTIPLTEKKT
                     FLKVTVKKETAQFHLKDVSTEEWKKVGPQKNMCILSGGFTGNFIGIAVHDLNKKRGSY
                     ADFEFFKYDGKDHL"
     gene            complement(4711..5121)
                     /locus_tag="ACG8LA_000553"
     CDS             complement(4711..5121)
                     /locus_tag="ACG8LA_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4064 domain-containing protein"
                     /protein_id="HFQ0202883.1"
                     /translation="MKRKWELLLGMVGGSLSLIFFGGLAVTLSNMSASEFKKSYQSLA
                     VDHSTLSLENTFGLLQDMTGLFAVVLFISLAFLAVALFLTAKGKYLTTATGLYFITGF
                     ILLIGTQFIAFPFAFFYFAAGAFSLYRVRMRKGA"
     gene            complement(5118..6041)
                     /locus_tag="ACG8LA_000554"
     CDS             complement(5118..6041)
                     /locus_tag="ACG8LA_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030599 - pectinesterase activity
                     [Evidence IEA];
                     GO_process: GO:0042545 - cell wall modification [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pectinesterase family protein"
                     /protein_id="HFQ0202884.1"
                     /translation="MRMKDKLIIGKNAIDTPTDFETIQEGIDYLAGLPDSHPKVLIVK
                     EGRYDEYIESRLSNFKLVGAGTVVISGNRFAKQEYLDGSQLGTFRSATFFLEGSNVVL
                     ENLHIENTAGPGEKVGQAVALFNSGDRVSLKNCRLSGYQDTLCTGPLPDLQKDGTPFC
                     TPASANPEYCRQTYEYCWIEGTVDFIFGGADAVFHQCHIHSLASKNPGYITAASTPKN
                     QKTGYRFESCTLTAEPDTRNVYLGRPWRPYANVLFEACKIGGHVHPTGWDNWDDKKNE
                     QTVKFSERNNNYETSIKRPEWIHLEKQGVQK"
     gene            complement(6038..6916)
                     /locus_tag="ACG8LA_000555"
     CDS             complement(6038..6916)
                     /locus_tag="ACG8LA_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="HFQ0202885.1"
                     /translation="MQLNDFLGAPSSRHTPSGKRLYREKQNGFMLEYYQLYLNELETV
                     PALYAYPEKEGPFPPVLYLHSHGGDFSVGKSELIHGAPYLASPSFAEVLTGMGYAVWS
                     IDAWGFEERGGISESELFKQFLLTGKTLWGMRIYDVISLIDYLETREDTDTQRLATIG
                     LSMGGLLSWWVTALDSRVKVCIDLAAQVDIEILLLHRRLDHHGFYYYVPNLLTAYTTL
                     AIQEKIAPRPRLSLVGKNDTMCLDEGVLKLRKGLDKKYQSMGSPENFSSFSLTGGHME
                     TQEMRNIWKQFIREHL"
     gene            complement(6903..8240)
                     /locus_tag="ACG8LA_000556"
     CDS             complement(6903..8240)
                     /locus_tag="ACG8LA_000556"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HFQ0202886.1"
                     /translation="MYDILTFGASIDELNTEAIQQAIDAAASDGGGTVVVPAGEFLTG
                     ALFLKSNVELHLSAGAVLKFSDDPKDYPVVHSRWEGVHRKVYASCIYAQNVENISVTG
                     FGTLDGNGKKWWHTFRNEPDNLAYPRPKLMSFHNCHRITVKDIKLIQSPSWTINPILC
                     SNATFDNLTILNPADSPNTDGIDPESCKNVRISNCHIDVGDDCIAIKAGTEDTYERIA
                     CENITITNCTMVHGHGGVVLGSEMSGSIRNITISNCIFQETDRGIRLKSRRGRGGIVE
                     DIRVSNIVMDNVMCPFILNLYYFCGPRGKEPYVWEKKAYPIDERTPAFRRIHFSNITA
                     RNVHASAGFIYGLAEQFIQEITFDNIDVSMAQDAVPGVPAMMTGIEEMSRQGFYIGFA
                     GKVSFNQMSIENHEGPAFLLENTKEISIEKFQSNQSENMDELVVRKNFAYAVE"
     gene            complement(8243..9346)
                     /locus_tag="ACG8LA_000557"
     CDS             complement(8243..9346)
                     /locus_tag="ACG8LA_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HFQ0202887.1"
                     /translation="MENWSKKLAKSIMERTPRLYEEKWYKGKWSYDYGVVLKGFQLLW
                     ERTQEKIYFDFIKDNIDYFVQEDGTIRGYSVEEYNIDHVNTGKLFFLLYKETGEEKYK
                     KAAELLSQQLANHPRTSEGAFWHKEIYPYQIWLDGLYMGSPFYAEFIQNFSEEKDYQD
                     VLRQFEISYKHLFDPKTNLLIHAWDEKKVQPWADPKTGLSHHFWSRSIGWYLMAAADT
                     YELLHEETDCSLLKEILEKTLAALLPYQEENSGTWYQVTTETKRKGNYLEASGSSMFV
                     YAMAKGIRLGLLNKEEWLPQVKKSHQGLLDEFVLETKEGWLNLNKNCQVAGLGGADQR
                     DGSYAYYISEPIICNDQKGVGAFLQALIEVEAL"
     gene            complement(9420..10928)
                     /locus_tag="ACG8LA_000558"
     CDS             complement(9420..10928)
                     /locus_tag="ACG8LA_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HFQ0202888.1"
                     /translation="MKKATLVKLGLSFAGILALAACGSSSSNSSSETEDGKAKITWLN
                     ILHHASPPTDTIVNLIEEKTDTELTFNWIPDASKEERLTTALASDELGDIVTLQIAML
                     KNSSVRNALKSGVFWDVSEYLKDYKNLSQISEDRIEAASIDGALYGVPIQKDYARAGL
                     VIRKDWLDNLGLDVPTTMDELYEVAKQFTENDPDGNGVDDTVGFGDRAPSDIRYTSFK
                     LFTSYFGAPNGWAVDDNGKFTPEFDTEEYMKALNFSRDLFENGYLAQDFAVTQKTDQQ
                     EQFAQGRTGIYTGMVDIKNLKTMGQGIQDDMELVPVNKISDGEGGGYHVWSEGNGIGG
                     LLAFPKSQVKDEAQLKKLLQFVDDLLEEDVYKLMTGGIEGTHYELNDDGSIEFIDMDL
                     WQQEVQPLSSSRPSEVTFSFKDTDPEKEFSNQLIKENEEFAVMDPSVPLDSPTNNEVG
                     SEIEKIVIDATVQYIMGQLDEDGFKKAVEDWKAQGGDRITQEYEEAYKAAAQ"
     gene            complement(10894..11586)
                     /locus_tag="ACG8LA_000559"
     CDS             complement(10894..11586)
                     /locus_tag="ACG8LA_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HFQ0202889.1"
                     /translation="MLQSLDKINGRLNRILQLVYLNFLWGGLVIAGLGVFTFGPASYA
                     MVAVIRKWLRSKETFPLTKTYFTYFKENYRETLLMSWIYGAIGIVLLVDLSFIHNWYL
                     RIALYIAAFIYVLSALYIFPIMAHYDWKGYFFKMKMAFLFGFSHLHYSLVLILSMVGI
                     YLMIIQTMPGVLTFIGGSLFFSAVTWTANSIFCHLEWKNSYTEKTEENKNIIKTVKEK
                     IYEKSNARKIRS"
     gene            complement(11608..12582)
                     /locus_tag="ACG8LA_000560"
     CDS             complement(11608..12582)
                     /locus_tag="ACG8LA_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFQ0202890.1"
                     /translation="MESVKKQEPFQLTLSKKEEKLRRRKKIIAGIKTNKFLYVMILPG
                     VLYFLIFRYLPMGGLVIAFQDYQPFLGIMGSPWVGFKHFIRLFTEPTFFTLLRNTLIL
                     FGLNIFVFFPMPIILSLLLNEVTNKRLKNGIQTIIYIPHFMSWVIIVSITYVFLNVDG
                     GVLNEFLATMGFEKISFLTSPEWTRTVYIGQVIWKELGWSTIIYLSAITAVDTQLYEA
                     AEMDGAGRLRKTWHVTLPAIRPVIITLLILKIGQTLDLGFEHMYLLLNSLNRSVAEIF
                     DTYIYTAGLKNGQLSFSTAMGLFKGVVGLFMVILANKIAKKLGEDGVY"
     gene            12882..13754
                     /locus_tag="ACG8LA_000561"
     CDS             12882..13754
                     /locus_tag="ACG8LA_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFQ0202891.1"
                     /translation="MKKKVSIGERSFTLFNNTFLILLALICIVPFLNIIATSFASTQE
                     VVAKKFILFPTTFSLDAYRYILSTPTIFRALAVSIGVTGVGTIVSMCATSLMAYGLSR
                     KYLFGRGFVNFLVVFSMLFSGGMIPTFLVVRSLGLVNSYWAMILPVAVNAMNMIIMRN
                     FFQALPDSLEESAKMDGCTDFGVFFKIMLPLALPSIATISLFYAVTYWNTYMTAILYI
                     NDSSKWPIQILLRQIVIVSSGMQAESSAVDVIPPAQTVKMAVIVIATVPMLIVYPFVQ
                     KYFVKGALVGSVKG"
     gene            complement(14212..16410)
                     /locus_tag="ACG8LA_000562"
     CDS             complement(14212..16410)
                     /locus_tag="ACG8LA_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0202892.1"
                     /translation="MKKSTVFYKIFLPMFLLGAVLVIGFSLFIYQNTYESIESSYLTD
                     KKNLLRQVKTNVEWKIRTIEYSFSTYGSTKNFSDIFKHPLTYTDYSTYSEIRKELNFI
                     ETIVMDDNNYDLVSLAGKWGVINGSLSQLTEEEVEKYQQKYINNKNNLFWQKKNKGIE
                     MVISLPMFEKEKYALGIATIEKHTIEQVVGESGEDILSIENEVGNLFTTQTVKNKEQP
                     TVLTDVDLDYNQLKVIREKDKTYIVLKSDYNNWIYRLEVDSSAIGAMIRNLRIGLVAV
                     SLTLVGLIGLLSYLFSDRFARPISQIQERLNLKSKGFSGKELDLVAQSVSRIIGEKEA
                     LSAHLVTQKPQLETLFVLSLFRNRVERRELDQRLQQFGYSSQNDCYYTALVQIDLLED
                     SHGGERDLLLLAINNMITEIVPKENRMLPIVLNEEMQATIYRMDKDDAEASKKVMEYC
                     RLIQKRVKEYLNLTISIGISNRFETLNESKQSVDRAKEALYYRVNTGPSSIIFYQEIV
                     PAAHEKTLIRYPIEEQNRLFEAIRSGNQEVKNLVHELIDALFAQNKNPLSREVVSVRL
                     INELVQLGQLLGVDSKNFDNMKQIYVKALNNYHPKELEKLVLEQLVLPITECSQAITD
                     HEFKNLSENIMHIVYTEYDRDLSLDVIADRLHYNPNYLSNVFKKETGEKFGDFVQNHR
                     LEVAKKWLKETNLSVKEIAERLQYRNPQNFIRFFKKKESITPGEYRKKYL"
     gene            16642..17634
                     /locus_tag="ACG8LA_000563"
     CDS             16642..17634
                     /locus_tag="ACG8LA_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFQ0202893.1"
                     /translation="MVTIKDIAKAAGVSHTTVSRALNNSSLIKNETKQKIRQLAKEMN
                     YSPNYSAKGLVNQKKYLIGLFFSSLHKGTSSNFLADSIAGIHSVLDTNYSLSVESIDV
                     VDLTEINLQRYDGLIVMSQSDDDQPFIDYLKEKEFPFVVVNRHINDPAVINVTADDAA
                     GVMQAVDYGIGCGHTKIAYIGGKKNFRSTKEREKGVLKSLKKASIPVNPAYFLTGDYS
                     LESGLQNMEYLLSLSDLPTLVFCGNDDIAIGALRAVHLAGLRVPQNISLIGFDDSPVV
                     SYLNPPLTTVRKPLKEMCQEGTKLLLDLIEGRTIEQSKIELSTLLILRESINYL"
     gene            17694..19115
                     /locus_tag="ACG8LA_000564"
     CDS             17694..19115
                     /locus_tag="ACG8LA_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagaturonate reductase"
                     /protein_id="HFQ0202894.1"
                     /translation="MKKLTKELVKKNEAPVKVLQFGEGNFMRGFIDWQIQQLNNQQLF
                     KGNVAIIQPLEQGLGNMMNQQDNLYTVILQGLSNGEIVDTSEIITVVEQMINPYDEWD
                     AYLSLAENDDLAYIVSNTTEAGIQFVETDNLTDTPPQSFPGKLTAFLYRRFKLNKAGF
                     TIIPCELIDRNGERLKEIILRYAEKWDLEPAFVEWLEKENVFCCSLVDRIVPGYPRED
                     AGVFNQRHNYEDQLMVKAEPFMLWVIEGPKELENQLPFKQAGLNVIITDDMTPYRERK
                     VHLLNGPHTAMVPLALLAELETVEEVMKDPLFSAYVDQLFNLELIPMLSLPKDELAIY
                     ADQIKERFLNPFAHHKLEAISLNSVSKFSTRLLPVFKKYIEEQNQVPPLITVSLAALL
                     LMYRGDQVKPHDDEKTISEFTDAWSDNGTAIPRLLQNAALWGEDLSQIPNVTDTVQEI
                     AAKIDQKGVRSVLQEMKGTMVHA"
     gene            19108..20607
                     /locus_tag="ACG8LA_000565"
     CDS             19108..20607
                     /locus_tag="ACG8LA_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HFQ0202895.1"
                     /translation="MLETLQPTMKLNRRDSVVVALTPIPKQTQLTIDQQTITTLEDIP
                     QGHKIALGDLKAGDNVIKYGYPIGHVTTDVTAGQWLHTHNVKTNLSGELDYRYEKDVH
                     PSHYLFENRTFQGYLRKNGKVGIRNDLFLVPTVGCVNGIAELIVKQFKEKHPDLGQFD
                     HITILKHPYGCSQLGKDHQNTREILADAVNHPNAGGVLVFGLGCENNTVPEFKKILGE
                     YDEERVKFLVAQDVYDEIEQGVALLEELLTAAENDQRISVPLSKLNVGLKCGGSDGLS
                     GITANPLLGAFSDYLIAQGGSTILTEVPEMFGAEQVLMARAENEEVFDSIVDLINDFK
                     QYFLSYGEPVYENPSPGNKAGGITTLEDKSLGCTQKSGSSPVVDVLQYGEKIRKPGLS
                     LLQAPGNDLVAASALASSDCQLVLFTTGRGTPFGSYVPTVKVSTNTTLFERKGHWMDF
                     NAGVLLEQPMEVILESFVQKIIAVASGEETKNEQNDVREIAIFKNGVTL"
     gene            20646..22040
                     /gene="uxaC"
                     /locus_tag="ACG8LA_000566"
                     /pseudo
     CDS             20646..22040
                     /gene="uxaC"
                     /locus_tag="ACG8LA_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628919.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0008880 - glucuronate isomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006064 - glucuronate catabolic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
     gene            22199..22882
                     /locus_tag="ACG8LA_000567"
     CDS             22199..22882
                     /locus_tag="ACG8LA_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnogalacturonan acetylesterase"
                     /protein_id="HFQ0202896.1"
                     /translation="MPTIHIAGDSTAAEKDENKRPETGWGEKISAYFSPEIQINNQAK
                     NGRSTKSFIQEGRLARLASQFQPNDFLFVQFGHNDQKIQEERGTLPFGSYLKNLQIFF
                     ECAKKANVQMVLLTSVTRRDYLENGTLNPDILGDYPKAMRAFAEKHHIPLLDVFSRSQ
                     ELFQTFSKEETKKFYLHLIPDTCKNYPEGLKDNTHFSPEGADKVARIIVELIKESRLP
                     LANYLQKGV"
     gene            22884..23720
                     /locus_tag="ACG8LA_000568"
     CDS             22884..23720
                     /locus_tag="ACG8LA_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase family
                     protein"
                     /protein_id="HFQ0202897.1"
                     /translation="MFPLNLGIRAHDLDVRNREEIVQKVSQLHLSHIQFAPQKAFPEQ
                     LKLTDMTLGSAAYFGEYFQKNNIELSILGCYINLSSKNQEVRAQALATFKQQIALCSA
                     YQAKMIATETGSVSVGYTKENFTEEAYQIARNSIIELVAHAENFGVTVAVEAGINHPI
                     YNYQLAKRLIDEVASPNLKIILDCANLMHKENHADQEKVIRGALDNLHGYITALHLKD
                     YIMENGKIRMVPVGKGCLDFRPVLHYIKYERPLMYATLEATPEIYVPEAIEHLQFIYQ
                     DC"
     gene            23731..25485
                     /locus_tag="ACG8LA_000569"
     CDS             23731..25485
                     /locus_tag="ACG8LA_000569"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0202898.1"
                     /translation="MEERIQKSYQKYHANAFQTLLHLYQGNYWRFAMSGLFFIIKHLP
                     SWLMPIAIANVINAASSKDSSQLQAIYFNAFLMACLIGQNILTNYFHVKYHSTSIRQV
                     EAGLRATLIKKIQELSIPYQKELQSGRIQSKIIRDVEAIQTLSSQVFVSGLNIAVNLF
                     VALGITLYKSPVVFMFFLLTVPLAAFVTLFFRKRIRQSNSDFRQEMEETSAKVIEVIE
                     LAPIARAHGLEKHETTRLNKHFTQIYEKGFHLDILQSVFGSVSWASFQIFQLICLIFT
                     GILALQGRIQPGDVVMYQTYFTTIVNSVSGMITLIPTISKGMESITSIGELLIAGDVE
                     TYHGKKKIQHLDGNFRFEDVSFLYPDSLKPIIDHFSLEVKAGETIAFVGPSGSGKSTL
                     LNLLIGFIQPTSGKIFLDDQPLDELDMRSVRNYLAVVPQTTLLFSASIKENITYGLKN
                     VSKERLDEVIEAAQLSSLIDQLPDGLDTLVGEHGNKLSGGQKQRISIARALIRQPKII
                     LLDEATSALDNQSEKKIQQALNYLTETPTTFIVAHRLSTIKEADKIVVIDEGKIVEIG
                     TYEKLLAQKGYFYRLKNE"
     gene            complement(25761..26102)
                     /locus_tag="ACG8LA_000570"
     CDS             complement(25761..26102)
                     /locus_tag="ACG8LA_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HFQ0202899.1"
                     /translation="MSNIYDSANQIEREIRELPEFKALKEAYEKVQANEEAHKLFKDF
                     QAMQIELQEKQMSGQEFSDEDAMKAQEMAVKIQSEEVINDLMQKEQGFSTIINDLNRI
                     IMTPVRDLYSE"
     gene            complement(26170..28341)
                     /locus_tag="ACG8LA_000571"
     CDS             complement(26170..28341)
                     /locus_tag="ACG8LA_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HFQ0202900.1"
                     /translation="MDFQSILEKIKAALISFWRWIRPYLGQFHRWRKRIWKKYHVNKL
                     ILLIGLICVLVTSIYLFILAKQANVETLKSGLSQSTVIYDKKNEEAGTLYAQKGTYVE
                     LNAISPYIQDAVISTEDRNFYEHHGFDIKGIARAAVRMVLSGGTSGGGGSTITQQLAK
                     NAYLTLDQTFDRKAKELFLAIEIEKKYSKEEILTMYLNNAYFGNGVWGVQDASRKYFG
                     VDATNVTLSEAATLAGMLKGPGIYNPIDHPKNANDRKNTVLSVMEENGKITKEQEQAE
                     SQTDISAYLNDTYDNSDSGYRYPYYFDAVIDEAVNEYGLDEEDVMNKGYKIYTALDQD
                     YQKQLEATYQNSALFPANASDGAMVQSASVALDPNTGGVQALVGRRGDHVFRGFSFAT
                     QMRRSPGSTIKPLSVYTPALEAGYKPSSILKDEPQSYYDAHNFDGTYQGEVPMYQAVA
                     QSLNLPTVWLLHEIGLQKGYDKAEEFGLPLAKSDKYYGLALGGLEKGVSPLIMAGAYS
                     AFANDGQMYTPHLITKIVDSTGAVIVDNTNKKPKQVISKETADEMTSMLLGTFSNGTA
                     AAANPAGYTIAGKTGTTETNFDATKANDQWMIGYTPDVVISTWMGYEESSKLHYLEGT
                     SGNVVGKVFKSAAEGILPYTSKTGFSVADAYATGGQVVAADQVGNTGNSNGESGNWQD
                     NLNQYGEQAKEGLKNFGDMVKEGVQGIGEAAKDLWRKYQGE"
     gene            28552..29409
                     /locus_tag="ACG8LA_000572"
     CDS             28552..29409
                     /locus_tag="ACG8LA_000572"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HFQ0202901.1"
                     /translation="MKITITLPMNHPETTIRDLLEKEWLVPRKVRHFLRIRKNVWINQ
                     QPALFHHEVKGNDQITLLFEETDYNYQEVQLGDAKHIRVLYEDEHLIIVDKPAGMKTH
                     PNEPTENSTLLNHLAAYLDTKQQRPYVVHRLDKETSGAVLFAKNPFVLPILGRMLEQK
                     MIYRRYQAIVWGEIAKDMTITNKIGRDRHDRRKRVVDDKNGQSALTHVTVNKVLSEQT
                     QVYCVLETGRTHQIRVHLAHKGHPIVGDPLYQNRTAERLMLHALELHMIHPFTQEKIV
                     GKALPGLWE"
     gene            complement(29480..30337)
                     /locus_tag="ACG8LA_000573"
     CDS             complement(29480..30337)
                     /locus_tag="ACG8LA_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HFQ0202902.1"
                     /translation="MYGGIEAGGTKFVCAVSDGGEILEKLSIPTTTPEETLDQVFEFF
                     DRYELKGIGIGSFGPIGIDKTKDNYGYVLATPKKGWAQFDFLGTIKERYNIPAAWTTD
                     VNAAAYGELKQGAAQGKNSCIYLTVGTGIGAGVVINEEIFSGIAHPEMGHIWVKRHPD
                     DHYEGTCPYHKDCLEGLAAGPSIEARTGIKGQDLPQDHPVWAIQAYYIAQALINYTLT
                     LAPEKIILGGGVMNQDHLLQKIRQQFVELMGGYMETPQVSEYIVRWGLPNESGIIGSL
                     LLAEHEHQK"
     gene            complement(30322..33024)
                     /locus_tag="ACG8LA_000574"
     CDS             complement(30322..33024)
                     /locus_tag="ACG8LA_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HFQ0202903.1"
                     /translation="MKKKVYIISHSHWDREWYMAYEQHHMRLIELIDDLLELFEVDPS
                     FNSFHLDGQTIILDDYLQVRPEKRQAIQQAINEGKLRIGPFYILQDDFLISSESNVRN
                     MLIGMEESRKWGTPVMLGYFPDTFGNMGQTPQLMKQAGISAAAFGRGVKPIGFDNQVL
                     EAENYSSQYSEMWWKGPDQTAIFGLLFANWYSNGNEIPVEKEAALAFWKQKLADAEQY
                     ASTNHLLMMNGVDHQPVQKDISKAIHLANELFPDYEFIHSNFTDYLEAVQKDVPEDLG
                     SVEGELTSQETDGWYTLANTASARVYLKQWNTKVQRQLENITEPLATMAYEVSGNYPH
                     DQLDYAWKTLMQNHPHDSICGCSVDSVHREMIPRFEKADEVGKYLAQDSLEQLTAAID
                     TTGFPKDSFPFVIVNTAGMDKTGEAEITIELERKRFAEGIPEQLYQELENLPKRKYHV
                     ETKSGATIPAILSEETVQFGYDLPKDRFRVPYMARMIKVTLPLENMPAFSWETFALVE
                     GEAKAEEKETMIHQSGRIIENGPLHLTIEKNGTITMEDRKNKRKLNNLHIFEDIGDIG
                     NEYIFKQPFCDQPILSSNKENSEVKVLVDTPEIAKISILQEMEIPVSADERLEKEQQM
                     VVEFRYRKAERSKEKRILQIKTIMTIRKDSKKIDFETTLDNQMKDHRLRVLFPTKLHV
                     EHHEADSIFEVVKRPNHVSKSWENPTNPQHQQAFVNIHDEEYGVTVGNFGLNEYEVTE
                     DGQIAVTLLRSVGELGDWGYFPTPEAQCLGEHRFNYSIELHGPEEKFSTYLHAYAAQI
                     PFSTQQIKHHEGTLISKQQYLTIKSETFAITALKRSKFSDKVVVRGFNMSSHLEKLEI
                     TKDNGKTVILNLLEEPTKQAVVPIIQPYEIRTIGFEEENECMAE"
     gene            complement(33037..34326)
                     /locus_tag="ACG8LA_000575"
     CDS             complement(33037..34326)
                     /locus_tag="ACG8LA_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HFQ0202904.1"
                     /translation="MAYKDIPKSVQKFMEDITQKCGDIHADWAKNFTAAFANTLLTTV
                     KKQNDGTTFLLTGDIPAMWLRDSTAQVRPYLVIAKEDEELADMISGLVKKQFFYINID
                     PYANAFNEEANGAGHQTDHTKMNDWIWERKYEIDSLCYPIQLAYLLYKNTGKTDQFNQ
                     SFIEGIKKILDVFKTEQDHEHSPYTFVRDTTRKEDTLINDGRGAKTAFTGMTWSGFRP
                     SDDTCRYGYLVPSNMFAVVVLGYVEEIFQTILDDKEIVQQTQKLKKEIQEGIQNHGRT
                     VNQKGQTIYAYEVDGMGNATVMDDSNVPNLIAAPYLGYCSEQEEDYLQTRRTLLSKEN
                     PYFYEGKYAKGIGSSHTPEKYVWPIALAMEGMTTSDKSEKERILNLLVATDAGTHLMH
                     EGFDVNNPENYTREWFSWANMMFCELVMDYFDIRVEK"
     gene            34476..35522
                     /locus_tag="ACG8LA_000576"
     CDS             34476..35522
                     /locus_tag="ACG8LA_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFQ0202905.1"
                     /translation="MNQPLYQTIFNDLQTAILTGELPVDSQLPTEKELSRTYKVSRIT
                     SKRALTELEQLGLIYRVRGKGSFVKSASPEQILASPTKTRRILFLLPYVADLSVGDFS
                     KGLNPVMQDKQIDVMMTTLDFLQNKTAKELINEFDGLIYYALDTEQHLDLLFELSLKE
                     FPVVILDKKIYELPFPTVLSDNFQGGALAASYLIEQGHSKIAYLFGTQTHPQSVRQRY
                     LGYLEALDKAGLTFHTSLDDKSATLDELLSYITKYEVTAFVCENDVVAIQTMNLLRQH
                     GYHIPEDFSIIGFDDIQAAALVDPPLTTIAQDFEQLGKLAGDALVTWLETKDRPSDSK
                     FPVSFIKRQSTKEK"
     gene            35524..37677
                     /locus_tag="ACG8LA_000577"
     CDS             35524..37677
                     /locus_tag="ACG8LA_000577"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HFQ0202906.1"
                     /translation="MNIGQIDTRHATANQPNFSNGNCQPYTGVPFGMNYFAPQTTDQN
                     GSWWFHPDDRVFQGYRLTHQPSPWMGDFSHMLFTPINGKLQENTLFHAQSSYRPEESI
                     FCPTHLSICQLRYGICSTLIPSMYGGILSIDYSKNDSGLLLSFPGRHQLFVIDPYTVE
                     GKITHFAGSEDPDFSFYFILRFEYPLTIDELAVSNKNSDSIPLYFEQTKKQTIRFGTS
                     FISSEQAAYNLELEQNQSKETYLAHSQEQWQSYFDRIQLTHHDQQQLRTFYHNLYRVF
                     LFPQTFYEIDPSGQKIHYDTTSRSIKPGVLYTNNGFWDTYKTVYPLYSLIAVEKYEEM
                     LEGFLNSYRESGYLPKWLSPDERGLMPGTLIDAVIADAAVKDIRRDLMPEFLTAMEKG
                     ATVQSKHPNYGRQGTEDYLTYGYVPNHYHESVNHTLDYAYSDFCISQVAKVLEEEEMT
                     KKYQQQSLNYQNIFDYESGFMRSKDKDGKFREPFSANRWGQDYAEGSAWQSSFAVYHD
                     FSGLIGKYGGSERYKEKLIELCNQPPTFDPGGYGFEIHEMSEMAAIEFGQLAISNQPS
                     FHYPYLFSYIGQPEMAQPLLKQLMTQTFDDSPMGYPGDEDNGSMAAWYIFNSLGFYPV
                     TPGTGEYVIGMPLIDKAVLLLSNGKELTIEATPNRPQQQFIHKIKRMDKEYTKLYFTH
                     QDLLKGGTISYQLGIIPHPKKYQAKDLPFSLSNYN"
     gene            complement(38150..39601)
                     /locus_tag="ACG8LA_000578"
     CDS             complement(38150..39601)
                     /locus_tag="ACG8LA_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFQ0202907.1"
                     /translation="MSVYQVLLVDDEYMILNGLKKIIDWQSLGFQIVATAENAKEGLA
                     VLEQRQIDLVVTDVTMPEINGLEFIEAAQKERHNFEFMILSGYQEFDYLKGGMQLGAV
                     NYLMKPVNKFELVESLKKIKTRLDQQNEQKNQQEIYQELLFSQWLNEELDEISEEEII
                     GQISEKQHRIVLIQLARTHDTLINRWLQERQQIFYYQRNYGDRVLITLLLEADEVDGF
                     CCFVQENFPDQEWLISIGEETDSLDKIPETFQQAKDNLQLHQFYGDKDEHVFYAVQAE
                     TKDQTIDFSSFRRVLQNKQLEVAQKMITDFFEQFQLAAMMPEDIRYSSFLLFMEIQRE
                     LIDLEDEEYLQGIEKIHQAKTVQELQQLLLSFIKKHQRQKKYSDNVEKVIVILHQHYQ
                     EPLTLKEVSENLHLNVMYLGQLFKKETKKSFSAYLNHLRMEKAKQLLLHSNQNINEIA
                     SEIGYNNTTYFSKLFKKIVGRSPKEYRENSGES"
     gene            complement(39598..41322)
                     /locus_tag="ACG8LA_000579"
     CDS             complement(39598..41322)
                     /locus_tag="ACG8LA_000579"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFQ0202908.1"
                     /translation="MNKFRILFSKGTLLNRLLRKYAVIMIGVTMTATVIFSIHTWEQN
                     QKQAENMTSDAVQSTSRMLNDKTTLSRIIKNQLVGNSEKIENVTTYLTKPIDQYLMYV
                     YEQQNSTDELVSFPNQIKDLYANYEELSAIYIVLNQLPEYYESSRENKGGEIKKGTPK
                     LLDAFYIKLPITQGGAESGSIFIGFQKKELDMILENLTSFNGLSLYMISGTTNRLYTF
                     HDNKIAKETFERQEMIITESLKKNSQLPIDDLEKNNFVQHQELSDDYRILAVLDKKSV
                     KIETGKNLAPLIIGIIILDNILLIFLYKTFKRYSQQVSIVMQAMDQTAAGNLETRIDI
                     TNTEYELKELSIGINEMLDSINQFVEDIYKLEIKQQDAHMRALQAQINPHFLYNTLEY
                     IRMYAISEGSEELADVVYAFSALLRNNTNQEKTITLKEELDFCEKYVYLYQMRYPNRV
                     AYHFMIDPDLEKIEVPKFVIQPLVENYFKHGIDFTRFDNALSVKVLQEGKRVRIIIKD
                     NGKGMTEKRLKQIEEKLSHPKVELHGSIGLQNVNERLRASFGSSYYMSLENNETGGLT
                     VSITFKEG"
     gene            complement(41315..41929)
                     /locus_tag="ACG8LA_000580"
     CDS             complement(41315..41929)
                     /locus_tag="ACG8LA_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HFQ0202909.1"
                     /translation="MLGKVLEELFIRIWVIIKLTLYFWIYTFAGGIIFGLGAAWKTVN
                     ELFYLYGFEYKEITIKRGWNIYKRNFLRGNLLFSLFLSGTALLSYNLYLSVQIKGLIF
                     LAIDFILLFALLCLFATYQYSMILDSEYTISVPNLLKLSFISVFSSFSSFLKIIIGSG
                     IILGVTWQFKGLILFGVIGLLTVWNGTMTTHWREELDKQLESYE"
     gene            complement(42274..43731)
                     /locus_tag="ACG8LA_000581"
     CDS             complement(42274..43731)
                     /locus_tag="ACG8LA_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFQ0202910.1"
                     /translation="MKLWKKLAFTGVSALLLGTLAACGGSGSKDQAEASNSDTLQMYQ
                     IGDKPDNFDQLMEVANKRIEKEIGVKVNINYIGWGDYEKKMNVIISSGENYDIAFANN
                     YVSNAQKGAFADLTELAPKYAEKAYNDLDEAYIKGNLVNGKLYAFPVNGNVFAQQVLT
                     FNKALLDKYDLSIDGIQSYADAEKVLKEFHEKEPNTAAFAIGQGFKVQGNFDYPLGNT
                     LPFAIDLDGDDSKIINQYDNETYIGLLRTMHSWYKQGLIPSDAATSNKDYPLEGNTWL
                     MRGETQGPYDYGDTILTNAAKQELVSKAITVPLKSTAQAQMANFVVSNTSKNKEKSVE
                     LLGLLNSDPELLNGLVWGIEGEAWEKVDGSDDKIKLLDGYQPNTHMSAWNTGNNKILY
                     TQESITDDMIAKRDQSIADAETSPILGFSFNTDSVKTELSNISNVMNQYLDGLNTGTV
                     DPDETLPKLKDALDKAGYDKVLKEMQKQYDEFRQE"
     gene            complement(43772..44692)
                     /locus_tag="ACG8LA_000582"
     CDS             complement(43772..44692)
                     /locus_tag="ACG8LA_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFQ0202911.1"
                     /translation="MKKKKVERVQVRSFNKTANFFSNIMIALFAISCILPFIFVIAIS
                     FTDESILSTHGYSFWPEKFSIFGYTYLFDQMQDKIFQALFVTVLVTVLGTLINSTATS
                     LYAYAISRSNFPFRRFFTVFCLITMLFSPGMVANYLVMTNLLQLKDTIWALILPMAVS
                     PFNIIVMRTFFKRSVSDSIIESARIDGASELRIFVQIVLPLAVPGIATISLFAALGYW
                     NDWFNALLYIQDDKLVPLQYLLMKIQSNIQYLTQNSGAGSQLTGGLASVPGESARMAI
                     VVISTLPIAISYPFFQKHFVKGLTIGGVKE"
     gene            complement(44704..45651)
                     /locus_tag="ACG8LA_000583"
     CDS             complement(44704..45651)
                     /locus_tag="ACG8LA_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFQ0202912.1"
                     /translation="MKKRKGFNHFFMNLWRYKALVLMAVPGMLWMIFFFYIPVMANVV
                     AFKNFHISADGFLASLRESPWVGWENFKFLFSSDQAFLITKNTILYNVAFILLNLLIS
                     VVFAIIMSELRNKRLVKVYQTMSLLPYFLSWVIISYFVYAFLSPDKGIFNQWITGHGG
                     EAVNWYNEPKYWPFILVFIGTWKGIGYNSIIYFASVMGIDPTYYEAAMVDGASKWQQI
                     KHVTIPQLIPLMTILTILAVGNIFRADFGLFYNIPRNSGALYDVTQVLDTYIYNGLTS
                     TGDFGMTAAAGLYQSVVGFVLLMITNTIARRFDSDSALF"
     gene            complement(46130..46849)
                     /locus_tag="ACG8LA_000584"
     CDS             complement(46130..46849)
                     /locus_tag="ACG8LA_000584"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HFQ0202913.1"
                     /translation="MRLDKFLADMGLGSRKEVKGLIKKGTIEVNGQVVKSDKAQVNEF
                     EDAVTYLGEIITYQKDFYYILHKPAGVISATQDNHDQTVIDLLEDQDYREDLFPVGRL
                     DKDTEGLLILTNDGVFAHQLLSPKKHVEKEYLAEVSGIMTEEDIRLFAEGLIIDGDEQ
                     TLPAKLQIDQVDQETETSIIRLILHEGKFHQVKRMVKAVGKEVLYLKRIRMGKFWLPK
                     DLNKGQYRPMTKEELEQVREK"
     gene            complement(46898..48544)
                     /locus_tag="ACG8LA_000585"
     CDS             complement(46898..48544)
                     /locus_tag="ACG8LA_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis C-terminal
                     domain-containing protein"
                     /protein_id="HFQ0202914.1"
                     /translation="MDNQRKPALDQLTPQEKMARGSAWMTASNIISRLLGAVYIIPWY
                     AWMGENAKAANGLFNMGYNIYALFLLISTAGIPAAIAKQTARYNSLNEYGTSRRLFIR
                     ALQMMGGLGLLFALFMYIASPWLAHASGGGEELIPTMRSLSIAVLVFPCMSVIRGYLQ
                     GNQEMMPYALSQIVEQVARIFYMLLATFIIMKVMDGDYVTAVTQSTFAAFIGMLASIL
                     VLLYFLKKHQAYTSAFIHYSENKINIATKELLLDTVKEAIPFIIVGSGVTIFKLVDQF
                     TFMKIMSASTEYSNAQLLDLFSIFSANPDKLTMVVIALATSIASTGLPLITEAVTLKD
                     RVGLAKLTSGNLQLFSFFMFPATFGVMLLAYPLNTLFYTPDSLGSNVLIQASFVGLFL
                     GLYMLVSNMLQGMFENKAAINYLVIGFLVKLLLQYPAIRLFEVYGPLLATMIGFAVSC
                     TLILKRIHEVARFKPSFVWRRTLLIFILTLIMLLASWITKMIFGAFLNEDSKFQSLLL
                     ILVVAGIGALVYGYLALKIRLAERLLGPGIARLRHKLKIK"
     gene            48723..49313
                     /locus_tag="ACG8LA_000586"
     CDS             48723..49313
                     /locus_tag="ACG8LA_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFQ0202915.1"
                     /translation="MTQEIKKLPVIFLGLFFITVGLNWFLLPHDIASAGVGAIGHLVE
                     TAFSIQRSVTVWSINLMMLLLAAVLLGKSVFFKTVAGSLLFPVVLEIVPKVEMISSHF
                     FSLISGSLLFSLGVYTLYTVGASNGGITIPPIIFHKFFRLPMPQGLLLTNSLIVFLNY
                     YVFGLLETLFVLLSITVSSLFMKILIRLSPVSRKFE"
     gene            49405..50910
                     /locus_tag="ACG8LA_000587"
     CDS             49405..50910
                     /locus_tag="ACG8LA_000587"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HFQ0202916.1"
                     /translation="MSFSLEDIRHLLLKENLLKEFVSTRGWHLDVPEKAEFLQLSYDS
                     RKADASTLFFCKGMNFKEEYLDSAIEQGIQYYVSEQPYENSAVGIIVTDIRKAMALLA
                     MAFYDYPQNKLKVIGFTGTKGKTTAAYFTKAILDHTTNKKTALLSTMNTTLDGKTYFK
                     SHLTTPESLDLYRMMSEAVENGMTHLVMEVSSQAYKTQRVYGLTLDVGIFLNISPDHI
                     SPIEHPTFDDYFYCKRQLILNSKTVVLNHESDYFDLLRETADLFQIPTITYGRSEESN
                     YQVIRSDKGTHGFTLSSHEDRLAICDTAYDILLAGGFNQENAASAIIAAALTGASSQD
                     AQDGLKEARVPGRMDQLIQSNGAHVYVDYAHNYLSLKTLLKFAKNEHPDGRVIVVLGS
                     PGNKAISRRHDFGKVLSETADIAFLTADDPAFEDPKKIAEEINEAITNPDLIVHYEMD
                     RPEAIRRALAESAPQDSVVIAGKGVDPYQKINGVDEPYEGDYAIVKRLIEE"
     gene            complement(50994..52346)
                     /gene="celB"
                     /locus_tag="ACG8LA_000588"
     CDS             complement(50994..52346)
                     /gene="celB"
                     /locus_tag="ACG8LA_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HFQ0202917.1"
                     /translation="MFDFLQKYLMGPMGKIAQLKIVRAVMAAGMASIPFTIVGSMFLV
                     LNILPLPFPFLEGFFNATFFKVSDLYMIVNTMTMGILSIYFAIVFAYELTSIERDEQK
                     LNVNPLTGALLSVFAFFMCIPELIMTDGKISLIASINETETVVNGIRMGSFVERLGTS
                     GIFTAIIMSIIAVELYCMCVKRNWVIKMPDVVPPGVSRSFTALIPTFVIAFVVMIING
                     LLVALGTDIFKMIAIPFGFVTQLTNTWLGVMVIYFLIHALWIVGIHGANIITSFLTPI
                     VLANMAANAQGANYPLAGEFNNSYVTVGGSGATLGLIIFIAFLAKSDQLKVLGKASLV
                     PGLFNINEPIIFGMPIVYNPYLAVPFFLAPMASATLAYFAIRLEIVKPMLAQMPWPSP
                     VGIGAFVGSGGDWKAAVLAVICAIIAFIIWFPFIKFYDNKLLNEEREKAAELASEKLK
                     "
     gene            complement(52346..52864)
                     /locus_tag="ACG8LA_000589"
     CDS             complement(52346..52864)
                     /locus_tag="ACG8LA_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202918.1"
                     /translation="MQDTVKRKIELEKKQLSLKNMYFNRYLIVRYLTAFFFFMNMQWM
                     ILLLSAKSLGSSLPMILILAILPAVGEQVKLYRKHQTNVPWTKWYFLFQSVFNLLVIP
                     VLFTSGFTFLYPFMANNNGGQLFVFILVVSGIFASAFIQYRLKKISLNQDQQYIRIKQ
                     YEKALYLGKENN"
     gene            complement(52880..53206)
                     /locus_tag="ACG8LA_000590"
     CDS             complement(52880..53206)
                     /locus_tag="ACG8LA_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HFQ0202919.1"
                     /translation="MAEKINSETLQVTSFDIIFHSGNARTLIHEAFRSMRKEMFEEVE
                     EKLRQANEEILHAHQSQTQLLKEYASGTKIEMEIIMVHAQDHLMTTMTLLEVAQEMNY
                     LYQKNK"
     gene            complement(53219..55198)
                     /locus_tag="ACG8LA_000591"
     CDS             complement(53219..55198)
                     /locus_tag="ACG8LA_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HFQ0202920.1"
                     /translation="MKQKEKLLLRYLIDHKKEYVTSQRLASELLLSDRTIRNYLQRIK
                     ELVEKNGGKIIAKPGYGYQLHILQRLTFDLFLSRQEIVPGYAREPQGFYESEDRQKYI
                     LNQLLLEDAILFMDDLAEELYISRSSLTKDMQEIKERLIPYSLKIVSKHGQGTWIEGE
                     ERNRRHFIMDTFFGNHYGNSLKEYLGQSRFFPDISFEELVIIILDETREAKLKVSDFI
                     IQNLTLHLALGIKRLREGFEIKELGIEQEVSKRVEYQVAQRIVQRIEVIAGVSFPEEE
                     IAYLTLHLMAKSNHKENQNDQELSKELAKVLKRLSQEFHFSLVEDLQLFNGLLDHLSP
                     MMIRLSRGIRIENPLTEEIKKENPKVFDAVKRHFSNMPALKNYTINEDEWAYLALHLM
                     AALEKERAAHKLHALIICATGYGSAQLLKNRVVSEFGKNITVVSVKGYYEINETTLKG
                     IDLIISSIDLSTMFFKIPVLHVSIFLNEDDVRKIRKVVGESIPYHSSDRPIPAFSLQQ
                     KKQIYTEQLSEKFFKTYTYEPKKEEILHDLLQKLSINEEEGYIREMRKQIQQRENMGQ
                     IIFSDTVAVPHPAVPVGIETKVAVALIPSGMQWDQYQEIHFVFLVSPSYVENEGITVV
                     TKAIVRLVDQLKVQQEILAEPIFENFSSKFIKLIE"
     gene            complement(55219..55533)
                     /locus_tag="ACG8LA_000592"
     CDS             complement(55219..55533)
                     /locus_tag="ACG8LA_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HFQ0202921.1"
                     /translation="MKKALIICAAGMSSSMMASKTTDFFKQKREEVLVDAVSATEGDN
                     MIKNSDFDLFLISPQTTMFLDKFKKLGESVGKPVVSIPFQAYVPIPTGIQKLAEVIEE
                     NI"
     gene            55701..55994
                     /locus_tag="ACG8LA_000593"
     CDS             55701..55994
                     /locus_tag="ACG8LA_000593"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_process: GO:0017000 - antibiotic biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase family
                     protein"
                     /protein_id="HFQ0202922.1"
                     /translation="MSITVNILYTSTNGQARKFAEEMVERNIVKAIRAEEGNEKYDYY
                     FPLEDPESLLLIDRWKDEEAIEKHHKSEMMAQINELRKKYKLKMKVERFTDLP"
     gene            complement(56072..57184)
                     /locus_tag="ACG8LA_000594"
     CDS             complement(56072..57184)
                     /locus_tag="ACG8LA_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HFQ0202923.1"
                     /translation="MTVKNKSKKKGRQQVDFYQSLQLDPFILKQKIREAASKKEKCMY
                     ICSLFLRSLFIVLFAICFIIIITTLFESKHKPYAVVLFCMLMSIRFVDFGYKISHSII
                     GLAIVMFSLLVAPYVQLIKWSVMGMLIHFILLSSILMATASDPKMGNASLYGFSYLFI
                     VYSLPKDSLNKNFFTQTSSLLFLFFCWFSVLLYRKHREKNKDKSLFKEIFLKGMYSQE
                     KIWMLIYAFGISLLIVAGEYVPFQRLMWAGFAFSSIVSSYGLMSIGFKERAVDRIIGS
                     LIGCVLFIGISQFIPFNWVGILGGLALGVCSTYRYKTVFNSFGALAITASLFGVPGAV
                     TIRIFENILGVCLGIMYIGVTEILIRKIREKHGLNH"
     gene            57337..58185
                     /locus_tag="ACG8LA_000595"
                     /pseudo
     CDS             57337..58185
                     /locus_tag="ACG8LA_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297185.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(58538..>59026)
                     /locus_tag="ACG8LA_000596"
     CDS             complement(58538..>59026)
                     /locus_tag="ACG8LA_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaA isopeptide-forming pilin-related protein"
                     /protein_id="HFQ0202924.1"
                     /translation="ERSQTAVVELTKENRLTPGGVVLTKIDDQSGEVLQGAVFELQDA
                     NGTVLQSGLTTGADGKLAIDGLAPGAYQLVETQAPTGYELDATPVTFKIEKEQEVAIF
                     LTKENRKVADSSDIRGNNPTSSGNKHLPKTGETIISQFILSILGVLLVFISIKFRKKR
                     NI"
BASE COUNT        17693 a        12042 c        10316 g        18975 t
ORIGIN      
        1 acgacttagt tatcttatca cgtctaaaaa catgtgtcaa ctcttttttg gaattttcat
       61 aaaatgtttc aatgaagcgc gacaacgttg tttaatatat cattaaaaaa aataaaggtc
      121 aagctaaaat attatttaag cttgacctta ttataatttc aacgattgtc aaaagtattg
      181 tttgcagctg tgttgccagt ttctatagat aaatcacagc ttttgaaaca taagttttgt
      241 actgcttcga ttcgcccgaa ttcttttgca gttatttggc aatgagaaaa gcagacatct
      301 tctataggct tttcaggaaa tgctactaaa tcaaaagctc gggaaggaag tgagtaacct
      361 ggagaaaggc atgcctgtac gtttttgatg tgtatgtctt tgactttcgt catttgcttt
      421 gattcaggta tttcttcagc cactgcttgc caactttctg gcatttgagc aaggtcattg
      481 ctattttttc tattgtattc attatgccag tccattatcc aagaaaaagg aaattgtaca
      541 tcaatcatat tcagattttc taccctgata ttttcgatca ctccccctct ttcttttgaa
      601 gatttcattc gaataccaca gtctgactga aaaaaatcga tatcgtgaat atatacgtca
      661 ctaactccag cactaacttc gctaccaata gttacaccgt atcctgaacg gattttacat
      721 ctagcaacct cgattcttga tgattttcga ttgactcttg caccattgcc atctctgcca
      781 gacttaatag caatacaatc atcaccacag gccaaatcac attcatagac acgcacattt
      841 gttgaagaat caatatcaat cccatctgta cttggtccat cattgttgcg gatgattact
      901 ttttctacta atacatcgtt agaataagtg atttgcaagt tccaaaaacc tgatttctga
      961 aaaatcaaat cacgaacaac aacatgttct gcatgataca gtaaacaagc gcgtggacgt
     1021 ttaatagcat aatccgcaat ccaacgaagt cccttttgat cgtattcagc tcttgtcccg
     1081 cttttttgat cttttcccca atacagctcc caccaatggt ctccttgacc gtcgattatt
     1141 ccttttcctt ctataagaat atctttcgcc gagagaacat tcaaaatcgc tgctggccat
     1201 ttcatttcta cgccggctac tcgtgtatcg atttctggaa atgcttcgat atctgttctc
     1261 cccttgagga ctgcaccttc ttcaaagata agatgactct tatcttttaa aaaaagggct
     1321 ccgactaaat aaatgccttt tggaataaat acaggtaagt gttctttcgc accttgatcg
     1381 attgcttttt gcagtattat tgtatcatct tgttgagtgt cgtttgtttt aaagttcaaa
     1441 gcattgataa tccctttttt tgtccgcaat acgtttctcc ctatctttca ttgatttttt
     1501 tcaattcttc accaataaat acagtttttg aacgattcag tgggtaacct actagcaaaa
     1561 tgattgcgga tacaaataag cagaatgctg gtaacaagtt tgccatcgta taaatccttt
     1621 cttgtactaa aactgattgg atggctccac ctgttgtaga cgattggtaa ccaatgagtg
     1681 ccagcataaa tccgcctacc gctcctgcac atgcttgtcc tacttttctc gcaaaagaat
     1741 ttactccata tactgttcca tcttctctta agcctgtctt atattgatga taatcaatca
     1801 cgtcagtaat gaatgcccag accatcaaat tgaataaacc agatcctaaa gtagcgataa
     1861 ataaaagaat cagatatacc catgcatttg ttatatgaag gaaatacatc agcaagtaca
     1921 tacatgaaga agcaagtaac gcaaatacgc ttgcttcctt tttaccaaat aattttgtca
     1981 gctttgtagc aaatggtgct aaaactacta ctgttccgta agtaaataaa agagcaacag
     2041 acattgcttg tttattatgg aagtaatcat tgaataaata agtcatattc gtcccagcta
     2101 aaatctgatt gatcacaatg aaaatgtcaa caatgactaa aataatcagt gctcgattag
     2161 ctaacaaacc ttttaccaac tgagaagcag atactttttc gtttttgaca actcttactc
     2221 tttcagtagt caatttacaa gttaacatat atgcgacaaa tgctattgca gcacatccga
     2281 ttgaaatcca aaagaaatga ttccctgaaa cgacttgttg tccactcttg ttatgggtat
     2341 acattaaaat cggaatgaag aatcctgtag ttgatccgcc aatcgcagaa ccaatgcttc
     2401 ggaacgtgga caacgaggtg cggtcattag gatttgagct aattgctgct gccattgctc
     2461 catacgggat attgattgtt gagagaaaaa tcccataaac aatgtatgaa acaaaaatat
     2521 aagcaatctt caccgtcatt ggaagatgtt ggacgaatgg caaaaacaaa atgacagtca
     2581 ctaagcaaaa tggatacttc atttttctga tccaaggaat aaatcggcca gtttctgtta
     2641 actctgagac atcacataat cttccaacca tcacatcagc aaacgcatcc aaaattctcg
     2701 aaatcaagaa taacgtacct acgattgccc ctgaaacgcc aagaacattc gtataataaa
     2761 tcatcaagaa actattgact aaacctaaaa taaaacagtt acctagatca ccgaacatgt
     2821 agcctatctt atcggaaatc ccaaattcct ttttttcttt ttttattgta tttgctgtaa
     2881 cagcattttg tgaaagcatt tgaattcctc ctacctcttc tagtaaacgt tttcaaaatt
     2941 ataactcttt ttttcttgtt tttatattca caatgttggc tttttattgc attatcttga
     3001 cagataaaaa acaaaaaata atctaaaaac attgatgcat aagattgata acttttttta
     3061 cataacaata tatacaaaca aaaaaattca ctaactagtg aaaataagtt agtgaacctc
     3121 atttattaaa gaattaaatt acagatgatc ttttccatca tacttgaaaa actcaaaatc
     3181 agcataactt cctctttttt tatttagatc atgcactgct atcccgataa aatttccagt
     3241 aaaccctcct gagagtatac acatgttttt ttgcggacct actttcttcc attcttcagt
     3301 tgatacgtct ttcaaatgaa actgtgctgt ctctttcttt acagtgactt tcaaaaaagt
     3361 cttcttttct gtgagtggaa tcgtccaatc ttctatttgt gctactccgt tttctgattc
     3421 tatcatacgt aggcattttc ccttgtcctc attccaagta acataacaat aaatataatt
     3481 ggattcattt aagtacagta ccagtccagc catctgatta aaattattag gcatgtattc
     3541 aaatgctgtc tccgcatcaa aagtaaaatc cgtttgccga atagctaaca aatgatgttc
     3601 gaaggtagat tgaagagatt caccggaaat cagacgtaaa aaacctggtc tacattttgt
     3661 atcacaccaa tcagcatttg gcaaaatgcg tctggcattc cagttcttct ttagctctcc
     3721 ttcaaatgta tccataaact gatgatcttt ttcttgttgt acctcttcat ttgtctcaat
     3781 cattatttct tccatcggag ttgtctggct atctttaagt cttaaccaat cgtcggacgt
     3841 ccaatacact tcttgaatag cggtttctct tcccaaaata gccgcaccgt ttaatggtct
     3901 ggtacaaaga tatgtcatgt accatcttcc tgacggggtt tgtactaagc tcccatgtcc
     3961 tgtacattgc aatgtagaag caggtttgtc actagctgtc agcataggaa aaccaggatc
     4021 aagctcgtaa ggaccagtaa tattctttgc tcggcaaact gtaactgaat gtcctcttcc
     4081 tgtaccgcct tctgccgtca tcaaataata atacccgtta cgaaaataca aatgtggtgc
     4141 ctccgttttc gctaattctg tacctgcaaa tattttatag atgggaccat caagcttctt
     4201 cttctctgca tcatattctt gtaatacgat accgctggat ttattcggtg tgtccagacg
     4261 ataatcccat agttcattga caagccattt ttttcccgtt tcaagatcat ggaacaaaga
     4321 aggatcaaag ccgttactat ttaaataaat tggttcggac caaggacctg tgatctcaga
     4381 tgcagtgatc aaataattgt ggacatcttt aaacggacgg cctgcacttt tgacatctgt
     4441 gtaaacaaga taaaacaatc catcagcata actgatttgt ggcgcccata tacttccatt
     4501 tgtaggattt ccttgcaaag atacttgagt ggtcaaaata tccgttgtat gtgaccagtt
     4561 gactaaattt ttcgactcat atactcggat tcctggaagc cattcaaaag aggagacaat
     4621 aatgtaatac cgctctttca ctcttaatat attaggatct ggattgaatc ctcttaaaat
     4681 aggatttttc actttgatag tctgcatgat tcaggctcct tttctcattc ttactcgata
     4741 taaactgaat gccccagctg cgaaataaaa aaatgcaaaa ggaaacgcaa taaactgagt
     4801 gccaatcaac aatatgaatc ctgttataaa atacaaacca gtggcagttg ttaagtattt
     4861 tcctttagca gtcaaaaaca atgctactgc taaaaaagca agtgaaataa acaacacaac
     4921 ggcaaacaga ccagtcatgt cctgtaataa tccaaatgta ttttctaaag acaaagttga
     4981 atgatctaca gcaagcgact gataactttt tttaaactct gacgcagaca tattacttaa
     5041 agtaactgct aacccgccaa agaaaatcaa agatagactg ccaccgacca ttcctagcaa
     5101 tagttcccat tttcttttca tttctgaacc ccctgctttt ctaaatgtat ccattcaggt
     5161 cttttgatcg atgtttcata attgttatta cgttcagaga atttgacagt ctgttcattt
     5221 ttcttgtcat cccaattatc ccaaccagtt gggtgaacat gcccacctat cttacacgct
     5281 tcaaataaga catttgcata cggacgccac ggtcttccta aatagacgtt tctagtatca
     5341 ggttctgcag tcaaggtaca gctttcaaaa cgataccctg ttttttgatt tttcggcgta
     5401 gatgctgctg tgatgtatcc aggattttta ctggctaagc tatggatatg acactgatga
     5461 aaaacggcat ctgccccacc aaatatgaaa tccaccgttc cttcaatcca gcaatattca
     5521 taggtctgac gacaatactc aggattggca gaagccggtg tacaaaaagg agtaccatct
     5581 ttttgcaaat caggcaacgg acccgtgcat aaggtatcct gataaccaga tagtcgacag
     5641 ttttttaaag atacgcgatc tcctgaattg aataaagcaa cagcctgtcc taccttttct
     5701 cctggacctg ctgtattttc gatgtgaaga ttttctaata cgacattcga tccttctaag
     5761 aaaaaagtag cacttcggaa agtccctaac tggctaccgt caagatactc ctgttttgca
     5821 aaacgattac cggagataac tactgttcct gctcccacaa gtttaaaatt ggataatctg
     5881 ctttctatat attcatcata tcttccttct tttactatca agacctttgg atggctatcc
     5941 ggcaggcctg ccaaataatc gattccttct tggatagttt caaaatccgt cggggtatct
     6001 atagcattct ttccaattat cagtttgtct ttcatcctca taaatgctcc cttatgaatt
     6061 gtttccaaat atttctcatt tcttgtgttt ccatatgacc gcctgttaaa gaaaaagaag
     6121 aaaagttttc tggactaccc attgattgat actttttgtc cagccctttt ctcagcttca
     6181 gtacgccttc gtccaagcac atcgtatcgt tttttccaac taagctaaga cgagggcgcg
     6241 gagcgatttt ttcttggatt gctaacgttg tataagctgt caatagattt ggcacatagt
     6301 aataaaaccc atgatgatct aggcggcgat gtagcaaaag tatttcgatg tccacctgtg
     6361 ccgctagatc aatacaaact ttgacacgag aatccaatgc tgtcacccac cagcttaata
     6421 agcctcccat agaaagacca atcgttgcga gccgttgagt atctgtgtct tcccttgtct
     6481 ccaaataatc gatcaagctg atcacatcat aaatacgcat tccccataac gtttttcctg
     6541 ttaataaaaa ttgtttgaac aactcgcttt cagaaatacc tccgcgttct tcaaatcccc
     6601 aagcatcaat cgaccaaaca gcatatccca ttcctgtcag tacttctgca aaagatggag
     6661 aagctaagta aggagcacca tggatcaatt cacttttccc gactgaaaaa tctccgccgt
     6721 gagaatgcag gtaaaggacc ggcggaaacg gtccttcttt ttctggataa gcatagaggg
     6781 ctggtactgt ttccaattca tttaagtaca attgatagta ttcaagcata aaaccgtttt
     6841 gtttttctcg gtataatcgt tttccactag gggtatgtct gctagatgga gcacctaaaa
     6901 aatcattcaa ctgcataagc aaagttttta cgaacaacca gttcatccat attttctgat
     6961 tgatttgatt ggaatttctc aatactgatt tctttagtat tttctaatag aaatgctggt
     7021 ccctcgtgat tttcaatcga catctggtta aaggaaacct tacccgcaaa gccaatataa
     7081 aatccttgtc tgctcatttc ctctattcct gtcatcatag caggaacacc gggaactgca
     7141 tcttgggcca tcgagacatc gatattgtca aatgtgattt cttgtatgaa ttgttccgct
     7201 aatccataaa taaaacctgc agaagcatgg acattccttg ccgtgatatt cgaaaaatgg
     7261 atccttctga atgctggtgt ccgttcatct atcggataag cctttttttc ccatacatac
     7321 ggttctttcc ctcgcggacc acagaaataa taaagattca gtataaatgg acacatcaca
     7381 ttatccatga ctatattgga tactcgaata tcttcaacga tcccgcctcg acctcgtcta
     7441 gatttcaatc gtattcctcg atcagtttct tggaagatac aatttgaaat ggtaatatta
     7501 cgaatactac cactcatttc acttcctaat acgacaccgc catgtccatg gaccatcgtg
     7561 caatttgtga tcgtgatatt ttcgcaagcg atcctttcgt acgtatcttc agtccctgcc
     7621 ttgattgcaa tacagtcatc tcccacgtca atatggcaat tactaatacg cacatttttg
     7681 catgattctg gatcaattcc gtctgtattt ggtgaatccg ctgggttcaa gatcgtcaag
     7741 ttatcaaacg ttgcattact gcaaagaatc gggttgatcg tccaacttgg tgactggatc
     7801 aatttaatat ctttcacagt aattcgatga cagttatgga aactcatcaa tttaggacga
     7861 ggataagcga gattatctgg ttcatttcta aaagtatgcc accatttttt tccatttcca
     7921 tctaatgtac cgaaaccagt gacagagatg ttctctacat tttgagcata gatacaggaa
     7981 gcataaactt ttcgatggac tccttcccaa cgtgaatgaa caacaggata atcttttgga
     8041 tcgtcagaga atttcagaac cgctcctgcg cttaaatgaa gttcgacatt gctttttaaa
     8101 aataaagctc ctgttagaaa ttcacctgct ggaacaacta cggtcccgcc tccgtcactt
     8161 gctgcagcat caatggcttg ttgtattgct tcagtattca attcatcaat tgatgcgcca
     8221 aatgtcaaaa tatcatacat atttataatg cctccacttc aatcaatgct tgcaagaatg
     8281 caccaacgcc tttttgatca ttacaaataa ttggttcact gatgtagtaa gcatatgaac
     8341 catctcgctg atctgctccg cctaaccctg ctacttgaca gtttttattc aagttcagcc
     8401 agccttcttt tgtttccaga acaaattcat caagtaatcc ttgatgtgat ttcttcactt
     8461 gtggaagcca ttcttctttg ttcagcagtc ccaaacgtat tcctttagcc attgcgtaaa
     8521 caaacatact actgccggaa gcttccagat aatttccttt ccgttttgtt tctgttgtta
     8581 cttgatacca tgtcccgctg ttttcttctt gatatggaag taatgcagcc agtgtctttt
     8641 ctagaatttc tttcagcaaa gaacaatctg tttcttcatg aagtaattca taggtatctg
     8701 ctgcagccat caaataccag ccaatcgatc ggctccaaaa atgatgggat agacctgttt
     8761 ttggatcagc ccatggttgg accttctttt catcccatgc atgaatcagc aaatttgttt
     8821 ttggatcgaa tagatgttta taactgattt caaactgtct caaaacatct tggtaatctt
     8881 tttcttcact aaaattctgg ataaattcag cataaaaagg agaacccata tataagccat
     8941 ccaaccaaat ttgataagga taaatttctt tatgccaaaa agctccttcg gatgtgcgtg
     9001 gatggtttgc caactgctgg gaaaggagtt ctgctgcttt tttatatttt tcttcgcctg
     9061 tttctttgta caataaaaag aaaagctttc ctgtatttac atggtcgata ttgtattctt
     9121 caacgctgta gccacggatc gttccatctt cttgcacgaa atagtcgata ttgtctttta
     9181 tgaaatcaaa ataaattttt tcttgggttc gttcccaaag taattggaac cctttaagta
     9241 cgacgccata gtcataagac cattttcctt tataccactt ttcttcatat aagcgaggtg
     9301 ttctttccat gatacttttt gctaatttct ttgaccagtt ttccattatt tgctctcctt
     9361 taaaaattaa aataggattt gggacaaata ccaagaagta tttgtcccaa tcgtctatat
     9421 tactgtgccg ctgctttgta tgcttcctcg tactcttgtg tgattcgatc gcctccttgt
     9481 gctttccagt cttctacagc ttttttgaat ccatcttcgt caagctgtcc catgatgtat
     9541 tgcaccgtag catcaatgac gattttttca atttctgatc ctacttcatt gttcgtcggt
     9601 gaatccaatg gcacagaagg atccattaca gcaaattctt cattttcttt gatcaattga
     9661 ttagagaatt ctttttcagg gtctgtatct ttgaaagaga acgtcacttc actaggacga
     9721 gagcttgata acggttgcac ctcttgttgc caaagatcca tatcgataaa ttcgatagaa
     9781 ccatcatcat tcaattcata atgcgttcct tcgataccgc cagtcatcaa tttatacaca
     9841 tcttcttcta aaagatcatc aacaaattga agtaatttct tcaattgtgc ttcgtctttt
     9901 acttgagatt tgggaaatgc tagcaagccg ccaataccat ttccttctga ccaaacatga
     9961 taaccgccgc cttcaccatc tgagatcttg tttacaggca ctaattccat atcatcttga
    10021 ataccttgac ccatcgtctt cagattcttg atatccacca ttccagtgta gattccagtt
    10081 cttccttgtg caaattgttc ttgctgatca gtcttttggg taactgcaaa gtcttgtgcc
    10141 aaatagccat tctcaaatag atctcttgaa aaattcaaag ctttcatata ctcttctgta
    10201 tcaaattctg gagtgaattt gccattatcg tctacagccc agccatttgg tgctccaaaa
    10261 taagaagtga aaagtttaaa gctggtataa cgaatatcac taggcgcacg atcgccaaaa
    10321 ccaactgtgt cgtccacacc atttccatca ggatcgtttt ctgtaaattg tttagctact
    10381 tcataaagct catccatggt agttggaaca tctagtccta gattatccaa ccagtctttt
    10441 cgaatgacta agccagcacg agcgtagtct ttttgtatcg gtacgccgta caaggcaccg
    10501 tcgatactcg cagcttcgat tctatcttca gaaatttgac ttaaattttt atagtctttt
    10561 aaatattctg atacatccca gaatacgcct gattttaacg cattgcggac agaagagttt
    10621 ttcaacatcg caatttgaag tgtaacgata tctcctagtt catcagaagc caatgcagtt
    10681 gttaatcttt cttcttttga agcatcagga atccagttga atgtcagttc cgtatcggtt
    10741 ttttcttcga tcaagttcac aatcgtgtct gtaggcggtg aagcatgatg caaaatattt
    10801 aaccaagtga ttttagcttt tccatcttct gtctctgaag aactgttact tgaactgctg
    10861 ccgcatgcgg caagtgctag aattcctgca aaactaagac ctaattttac gagcgttgct
    10921 tttttcataa attttctcct tcactgtttt aataatattt ttgttttctt ctgttttttc
    10981 tgtatatgag ttcttccatt ccaaatggca aaatatagaa tttgctgtcc acgtgactgc
    11041 ggaaaagaag agactgccac cgataaaggt taaaacacct ggcattgttt ggatgatcat
    11101 cagataaatc cctaccatac ttaatatcaa cactaatgag taatgaagat gtgagaatcc
    11161 gaataaaaat gccattttca ttttgaaaaa atatcctttc caatcataat gagccatgat
    11221 tgggaaaata tagagtgctg agagcacata tatgaacgca gcaatataca aagcgatcct
    11281 aagataccaa ttgtgtatga aagaaagatc cacaagtaaa acaatcccga tggcgccata
    11341 tatccagctc atcagcaagg tttcacgata gttttcttta aaatatgtga agtacgtttt
    11401 cgtcaaagga aacgtttctt ttgagcgcag ccattttcta atcactgcaa ccatcgcata
    11461 cgatgcagga ccgaaagtaa aaactcccaa acctgcgatg actaaaccgc cccacagaaa
    11521 attcaaataa accaactgta aaatacgatt tagccttccg tttattttat ctaatgactg
    11581 cagcatatct ttccctctct ttctatctta gtaaacgccg tcttctccta gctttttggc
    11641 aatcttatta gctaaaatta ccataaacaa tcctacgacc cctttaaaca atcccattgc
    11701 tgtactgaaa cttaactgtc cattcttcaa tccagctgta taaatatagg tgtcgaaaat
    11761 ttctgcaacg cttcgattca atgaattcaa taacaagtac atatgctcga accctaagtc
    11821 taatgtctga ccgattttta gaatcagcaa ggtaatgatt actggacgaa ttgccggcaa
    11881 tgtaacatgc catgttttgc gtaagcgtcc tgctccatcc atttctgcag cttcatacaa
    11941 ctgtgtatcg actgcagtta tcgctgaaag gtagatgatc gtagaccagc ccaactcttt
    12001 ccagatcact tgtccgatat atactgtgcg tgtccattca ggggatgtta gaaaactgat
    12061 tttttcaaat cccattgttg caaggaattc attcaatacc cctccgtcaa cattcaaaaa
    12121 tacataagta atcgaaacaa tgattaccca agacatgaag tgagggatgt aaatgatcgt
    12181 ttgaatcccg tttttcaatc gtttgttcgt tacttcattt aatagtaaag acaaaatgat
    12241 tggcatcgga aaaaacacga agatatttaa tccgaacaag atcaacgtat ttcttaataa
    12301 tgtaaagaat gtcggttctg taaacaaacg aatgaaatgt ttgaaaccga cccaaggact
    12361 tcccattatt cctaaaaatg gttgataatc ttgaaaagca ataacgagtc cccccatagg
    12421 aagataccta aaaatcaaga aataaaggac tcccggcaga atcatcacat ataaaaattt
    12481 attcgttttg attcctgcaa ttattttttt tcgtcttctg agcttttctt cttttttcga
    12541 tagcgtcagt tgaaatggtt cttgtttctt tacactttcc ataagcccct ccttagtttt
    12601 gtgaatgttt gctgcttatg acttcatgat agataactat ctgaattacg tatataatca
    12661 tttttaccgt aagtaaaaac gcttacatag caatgatttt tgtgctatac aaaacgataa
    12721 agtgtatttt ttcacaaata aactacgcat agcaaacctt ctattttttt ctatctgaca
    12781 cttagcatag gaaatgatta tatacgtaat ctttcaccga tgataaattg aacatataga
    12841 aacagaaaca tttaatttat tttgaggagg agcctatcta tatgaaaaag aaagtctcta
    12901 taggagaaag aagttttaca cttttcaaca atacgtttct aattttgcta gctttgatct
    12961 gtatcgttcc ttttttaaat atcatcgcta catcttttgc ttctacacaa gaagtcgtcg
    13021 cgaaaaagtt tatccttttt cctactacct tttctttaga cgcgtatcgc tacattcttt
    13081 ctacgccgac catttttaga gcacttgctg tttcgattgg tgttacaggt gtcggaacga
    13141 tcgtcagtat gtgtgcaact tcactgatgg cctacggtct ttccagaaag tatttgtttg
    13201 gtcgaggttt cgtcaacttt cttgttgtat tttctatgtt gttcagcggg gggatgattc
    13261 caacgttctt agttgttcgt tctctagggc tggtcaattc ttactgggcc atgatcctgc
    13321 ctgtggctgt taatgcaatg aatatgatca ttatgagaaa ctttttccaa gccttgccgg
    13381 atagtttgga agaatcagca aaaatggatg gttgcacaga ttttggtgta tttttcaaaa
    13441 ttatgctgcc attagcgtta ccgtctattg ctactatctc gcttttttat gctgttactt
    13501 actggaacac ttatatgact gctattttgt atatcaacga ttcatctaaa tggccgatac
    13561 agattctttt acgccaaatc gtcattgtat caagtgggat gcaagcagaa agtagtgccg
    13621 ttgatgtgat tccaccagca caaacagtta aaatggctgt tatcgttatt gcaacagtgc
    13681 ctatgctgat tgtttatcct tttgttcaga aatattttgt caaaggagca ctcgtaggtt
    13741 ctgtcaaagg gtgattatgt actgaacgca aaatggtagt tgtgtcagaa gtggtcagct
    13801 tcaagaaata agaaggcatt tacgaaaatt gcttcttaaa tttttgtgaa atttcggctt
    13861 atttttcgaa gaatctactc ctggaacacc gtgtatcaga ggttgtgaaa gagacgttca
    13921 gccttgagcg atgataaaaa ctctcacaaa cattgcgacg agtaacccac aggagcaata
    13981 agaagcgatt ttgaaaaata gcttcccata tttcacaaaa ttatgcctta ttgtcgatag
    14041 cctgtctctt gaacgccatt tattcgtaaa aaagaactgt gacaagactt ttgtcacagt
    14101 tctttttgcg tgcttagcct tgaaatttaa ctatccataa atacaaatac tagggttatt
    14161 ctaacttctt ttattgcttg aatcagtcca caagaaaaac agcctcttga ttcacaaata
    14221 tttttttcga tattctcccg gcgtaatcga ttccttcttt ttaaagaaac gaataaaatt
    14281 ttgcggattt cgatattgca atctttctgc aatctctttt acggagaggt tagtctcttt
    14341 caaccatttt tttgctacct ctaaacgatg attttgaaca aaatcaccaa atttttctcc
    14401 tgtttccttt ttaaatacat tacttaaata gttagggtta taatgcaacc tatcagcgat
    14461 cacatctaaa gacagatcac gatcatattc tgtgtagacg atatgcataa tattctccga
    14521 caaattttta aattcatgat cagtgattgc ttgagagcat tctgtgattg gcagaactaa
    14581 ttgttctaaa acaagttttt ctagttcttt gggatgataa ttgttcagtg cttttacata
    14641 aatttgtttc atgttatcaa agttttttga atctactccc aataactgtc ctaattgaac
    14701 gagttcattg atcaagcgga ccgaaactac ttcccgactc aaaggatttt tattttgtgc
    14761 aaacaatgca tcaatcaatt catgtactaa attcttcact tcctgatttc cagaacgaat
    14821 ggcttcaaac aatcgatttt gttcttctat cggatatcta ataagtgttt tttcatgagc
    14881 agcaggaacg atttcctgat aaaaaataat tgaacttgga ccagtattta cacgataata
    14941 cagggcttct tttgcccgat caaccgattg cttgctttca ttcagcgttt cgaaccggtt
    15001 actgatgcct atactgatag ttaaattcaa gtattctttt acacgttttt gaatgagtcg
    15061 gcaatactcc atgacttttt tgcttgcttc tgcatcatct ttatccattc gataaatagt
    15121 ggcttgcatt tcttcattca aaacgatcgg cagcattcga ttttcctttg gcacaatttc
    15181 cgtgatcatg ttgttgatcg ctaaaagtag caaatcacgc tccccaccgt gactatcttc
    15241 taacagatcg atttgaacca aagctgtata atagcagtca ttttgagaac tataaccaaa
    15301 ttgctgcaac cgctgatcta gttctcgcct ttctactcga tttctaaata aactaagtac
    15361 aaatagcgtt tccagctgtg gcttttgggt aactaagtgt gcacttaacg cttctttttc
    15421 tcctatgatc cgactgactg attgagcgac caaatctagt tctttcccac tgaatccttt
    15481 tgatttaaga ttcagacgtt cctgtatttg agaaatcgga cgggcaaatc tgtccgaaaa
    15541 taagtaggaa agaagaccaa tgagtcctac cagtgttaaa gacactgcaa ctagcccgat
    15601 tctcagattg cggatcattg cgccaattgc actagagtca acttctaatc tgtaaatcca
    15661 attattataa tctgatttca gtactatata cgttttatct ttttctctta tcactttcag
    15721 ctgattgtaa tctagatcca cgtccgttaa tacagttggt tgctctttat tttttactgt
    15781 ctgagtagta aaaaggttgc caacttcgtt ttcaatagaa agtatgtctt ctccactttc
    15841 accaacaact tgttctattg tatgtttctc tatcgtagca attcccaatg catatttttc
    15901 tttttcaaac attggcaaag aaatcaccat ttcgattcct ttgtttttct tttgccaaaa
    15961 taaattattt ttgttattta tgtacttctg ttgatacttt tcaacttcct cttcggtcag
    16021 ttgactcaac gatccattga ttactcccca tttaccagcc aaactgacta aatcataatt
    16081 attatcatcc ataacaatcg tttctataaa atttagttct ttcctgattt cagaataagt
    16141 ggagtaatct gtatatgtca gcggatgctt gaatatgtcc gagaaatttt tggtcgaacc
    16201 atacgtagaa aacgaatatt caatcgttct aattttccat tcaacgttag ttttaacttg
    16261 cctgagcaaa ttctttttgt ctgttaaata actcgattcg atcgattcat aggtattctg
    16321 gtaaatgaat aaactaaatc ctatgacaag tacggctcct aataaaaaca tcggtaaaaa
    16381 tattttataa aatactgtac ttttcttcat tttcttcctc tcctcctttt aaaataaaag
    16441 gctttcattt ttctgtaaaa ttgatactca tctaattaaa tgagcattcc ccgctttcaa
    16501 gaatagcata attaaaaata aaaatccaag taatttttaa cgtgtgcaat cttttcatat
    16561 caaagatcta ttgacttatc gtagttatcg taatatgatg aatgcgttaa caaaaagtga
    16621 aaaagtaagg aaaatgatgg aatggtaacg atcaaagata tcgctaaagc agctggcgtt
    16681 tctcatacga cagtttctcg tgctttgaat aacagcagtt taataaaaaa tgaaacaaaa
    16741 caaaaaatac gacaactagc taaggaaatg aattattcgc caaactatag tgcaaaaggt
    16801 ttagtgaatc aaaaaaaata tctaatcgga ctatttttct caagtttgca taaaggaact
    16861 tcatcaaatt tcctagcaga ttccattgca ggcatccatt cagtattaga cacaaattac
    16921 agtttatctg ttgaaagtat cgatgttgtt gatttaacag aaatcaacct gcaacgctac
    16981 gatggactga tcgttatgag tcaaagtgat gatgatcagc ctttcatcga ctatctcaaa
    17041 gaaaaagaat ttcctttcgt tgttgtcaat cgtcacatca atgatccagc ggttatcaac
    17101 gtcactgccg atgatgcggc cggtgttatg caggcagtag attacggtat tggatgcgga
    17161 catacgaaga tcgcttatat tggcggaaag aaaaattttc gttcgacaaa agaacgggaa
    17221 aaaggggtat tgaaaagtct aaaaaaagcg agcatccctg tcaatccagc ctatttttta
    17281 acaggagatt acagcttaga aagcggcctc caaaacatgg aatacctatt atcactttct
    17341 gacctgccta ctctggtttt ttgcggcaac gacgacatag cgattggtgc attgagagct
    17401 gtacatttag ctggcctccg tgttccccag aacatttctc tgatcgggtt cgatgattct
    17461 ccagtcgtct cctatctcaa tccgccgctt accaccgtac gtaagccttt gaaagaaatg
    17521 tgtcaagaag gaacaaagct tttactagat ttgatcgaag gcaggacgat cgaacaatct
    17581 aaaattgagc tctccacctt gttgatcctt cgtgagtcga tcaattactt gtaaactaca
    17641 agtaatttta tataaaaatg ttaacgtgtg cataacacag aaaggaagtt tatatgaaaa
    17701 aactgacaaa agaattagtg aaaaaaaacg aagcacctgt aaaagttctt cagtttggtg
    17761 aaggcaattt tatgcgtgga tttattgatt ggcagattca gcagctgaat aaccaacaat
    17821 tgtttaaagg taatgttgca atcattcaac ctttagaaca aggtcttgga aatatgatga
    17881 accagcaaga taatttatat acggtcattt tacaaggact cagcaatggc gaaatcgttg
    17941 atacttccga gattatcacc gtagtagaac aaatgatcaa tccttatgat gaatgggatg
    18001 cttatctatc tctagcagaa aatgacgact tggcctatat cgtctccaat acaacagagg
    18061 caggaatcca attcgtggag actgataatt taacagatac tcccccacag agcttcccgg
    18121 gcaaactgac agccttttta taccgacgtt tcaaattaaa caaagctggc tttaccatca
    18181 ttccttgcga actgattgac agaaacggcg aacgtctaaa agaaatcatt ttacgctacg
    18241 cagaaaaatg ggatttagaa cctgcttttg ttgagtggtt agaaaaagaa aatgttttct
    18301 gttgtagttt agttgatcgc atcgtcccag gttatcctcg cgaagatgca ggtgttttca
    18361 atcaacggca taactatgaa gatcaattga tggtcaaagc agaaccattc atgctttggg
    18421 tgatcgaagg gcctaaagaa ttggagaatc aactaccatt caaacaggct ggcttgaatg
    18481 tcatcatcac agatgatatg actccttatc gtgaacgtaa ggtgcatttg cttaatggac
    18541 cgcatacagc gatggtccct cttgctttgt tggcggaatt ggaaactgta gaagaagtaa
    18601 tgaaagatcc tttattctcc gcatatgttg atcagttatt caatctagaa ttgattccta
    18661 tgctttcttt acctaaagat gaattagcca tttatgctga ccaaatcaaa gaacgtttct
    18721 tgaatccttt tgcccatcac aaattagaag cgatttcatt aaatagtgtt tcaaagttca
    18781 gcacccgtct gcttccagtg ttcaagaagt atatcgaaga acaaaatcag gtaccaccgt
    18841 taatcactgt ttcactagct gcgctacttc ttatgtatcg aggcgatcaa gtaaagccac
    18901 atgatgatga aaagacgata agcgaattta ctgatgcttg gtctgataat ggaacagcta
    18961 ttcctcgatt attgcaaaac gctgcgcttt ggggagaaga tttgtctcaa ataccgaatg
    19021 tgacagatac agttcaagaa atagctgcaa agatcgatca aaaaggtgtc cggtcagtat
    19081 tacaagaaat gaaaggaacg atggtccatg cttgaaaccc tgcaaccaac aatgaaatta
    19141 aatcgacgag acagtgtggt cgtcgcatta acccctattc caaaacaaac acaactgacg
    19201 attgatcagc aaacgatcac cactcttgaa gatatcccgc aaggtcataa gattgcattg
    19261 ggtgatttga aagctggaga caacgtgatc aaatatggct atccaatcgg tcatgtgacg
    19321 acagacgtaa ctgccggtca atggctgcac actcataatg taaaaaccaa tctttctggt
    19381 gaattggatt atcgatatga aaaagatgtc catccaagtc attacctttt tgagaaccga
    19441 acatttcaag gttacttgcg aaaaaatgga aaagtaggga ttcgtaatga tttgttttta
    19501 gtacctaccg ttgggtgtgt gaatggcatt gctgaactga tcgtcaaaca gttcaaggaa
    19561 aaacatccag atctgggaca gtttgaccat attacgattt taaagcatcc ttatggctgt
    19621 tcgcagcttg gaaaagatca tcaaaatact cgagaaattt tagcggacgc agtaaatcat
    19681 cccaatgccg gaggagtttt agtatttgga ttaggttgtg agaacaatac agttcctgaa
    19741 ttcaaaaaaa ttttaggtga atatgatgaa gaacgagtga aatttctagt ggctcaagat
    19801 gtttacgatg agatcgaaca aggtgtggct ctattagaag agcttttaac agcggcggaa
    19861 aatgaccagc gcatatcagt cccgctctct aagttgaatg tcggtttgaa atgcggcggt
    19921 tctgatggtc tatcgggaat aactgctaat cctttacttg gtgcattttc tgactacttg
    19981 attgctcaag gaggcagcac gatcttaaca gaagtgccag aaatgtttgg cgcagaacaa
    20041 gtattgatgg cacgagcgga aaatgaagaa gtttttgact caatcgttga cttgatcaat
    20101 gacttcaaac agtatttctt gtcttacggg gaaccagttt acgaaaaccc atctcctggt
    20161 aataaagcag gtgggatcac tacattagaa gataagtctt taggctgcac gcaaaaatca
    20221 ggaagctctc ctgtcgttga tgtgctacaa tatggcgaaa aaatcagaaa accagggctt
    20281 agtttattgc aagctcccgg gaatgatctt gtagctgcct ctgctcttgc ttcatccgat
    20341 tgccagttgg tcttgtttac cacaggaaga gggactccgt ttggctcata tgtcccaacg
    20401 gtcaaggtat ctacgaatac aactcttttt gaacgcaaag gtcattggat ggattttaat
    20461 gcaggcgtct tattagaaca accaatggaa gtaatcttag aatcgtttgt tcaaaaaatc
    20521 atcgctgtag ctagtggaga agaaacgaaa aatgaacaaa atgacgttcg agaaattgcc
    20581 atttttaaaa acggagtaac actttgattt tcataaaaca gtataaaaag aaagaaggaa
    20641 gatttatgtt tttatctgat gattttttat taaaagacga ttgggcgaaa aagctttacc
    20701 attcctacgc aaaaaacatg cccattattg attatcactg tcacttagat ccaaaagaaa
    20761 tttacgaaaa caacaatttc agcaatctga cagaagcttg gttaggaggc gatcattaca
    20821 aatggcgctt gatgcgagct tgcggcgtgc ctgaagaaaa aatcacagga aatgcttctg
    20881 attttgaaaa atttttagct tggtgtcaaa ccgtaccaaa aattatcgga aatccgcttt
    20941 acagttggtc acatcttgaa ttgaagcgtt tcttcggtat tgacttgttg ataaatgaag
    21001 aaaatgcaga gaaaatttgg acacaagcaa atgaaatttt ggcagctcct gattttcgcc
    21061 gtcgggaaat cgcaaaaaaa tcgaatgtag aagtgatttg tacaacagat gatcccgcag
    21121 acgacttgca ctatcatcag ttgcttgctc atgaagaacc agatttgaag gttctacctt
    21181 cattccgtcc agataaagca ctcaatattg aaaaagaagg atttaatgca tgagtcacac
    21241 tactggaaga agcagctgac caaacgatca ccacctatca agaactgata gaagtcttag
    21301 ggcagcggat agaatacttc catcaacatg gatgtcgtgt ttccgaccac gctttagaca
    21361 tcttacgcta taaagaagcg gatgaaacag tattagaaga gatttttcaa aaagcacgag
    21421 ctaacaaact attatcttca gatgaaatcg atgcttatcg tacagaaaca ctgatacatt
    21481 tgacccactt ctatcattct cataattgga cgatgcagct gcacatccat gcttatcgta
    21541 actgtaatac acaaatgttg gaaaaattag ggcccgatac cggctatgat ggaatgaatg
    21601 atctttcttt gactattcct ctgcaaaaat tattgaaccg tgcagaagaa acggatcagt
    21661 tgccaaagac gatcctttat tcattgaatc cgaatgacta tcctgcgatt ttagctttga
    21721 tgggctgttt ccaaaaagaa cagaatggaa aactgcagtt aggttctgga tggtggtaca
    21781 acgatactcg agctggtatg cgcgatcaat tgacacaatt tgctgatggt agtgctttgg
    21841 ggaattttgt cggcatgctg acagattcaa gaagtttcct gtcctacact agacatgaat
    21901 atttccgtcg tgttctttgt gaatttttag gcgaaatggt catgcgagga gaagcacctg
    21961 aagatgaaca acttttagga agtctagttc aagcgattag ttatacaaat gctaaaaatt
    22021 actttggctt ttttgcctaa ttgattaata gtaacagtaa cgaatcaaaa acaggatagt
    22081 gaaataacgg aatccgttta tccacgtttt agagaagaag acggaccaaa tttgctccgt
    22141 cttcttctct tgctgttctg cttcattgcc tataaacctt tatgaaagaa gagataacat
    22201 gcctactatc catattgccg gtgattctac tgcggcagaa aaagatgaaa acaagcgtcc
    22261 cgagacaggt tggggagaaa aaatctctgc ttatttttca cccgagatcc agatcaataa
    22321 ccaagcaaag aatggacgca gcaccaaatc atttatccag gaaggaaggt tagcccgtct
    22381 agcttcacag tttcagccga atgatttctt atttgtacaa tttggacata acgaccagaa
    22441 aatccaagaa gaaagaggta cgcttccctt cggtagctat ttaaaaaatc tgcagatatt
    22501 ttttgaatgc gcaaaaaaag cgaacgtcca aatggtctta ctgacatctg tgacgcgacg
    22561 agattactta gaaaacggaa cattgaatcc agatatactt ggagactatc caaaagcgat
    22621 gcgtgcattt gctgagaaac accatattcc tcttttagat gtgttctcaa gatcacaaga
    22681 attgttccag accttctcaa aagaagagac aaaaaaattc tacctgcatc ttatacctga
    22741 tacttgtaaa aattacccag aaggactaaa agacaatacc cactttagtc cagaaggcgc
    22801 tgataaagtt gcccgaataa ttgttgaatt gataaaagaa tcccgtctgc ctcttgctaa
    22861 ttatttacaa aaaggagttt gagatgtttc cattaaattt aggcatccgt gcccacgatt
    22921 tagatgttcg aaatcgtgaa gaaatcgttc aaaaagtatc acagcttcac ttgtcccata
    22981 tccaatttgc accacaaaaa gcatttcctg aacaacttaa attaactgac atgacacttg
    23041 ggagtgctgc ctattttggt gaatacttcc aaaaaaacaa tatcgaactt tccattttag
    23101 gatgctatat caacctatcc agcaaaaatc aagaagttcg tgcacaagca ttggcaactt
    23161 tcaaacagca aattgctctg tgctctgcct atcaagccaa gatgattgct acggaaaccg
    23221 gtagtgtctc tgtcggttac acaaaagaaa attttactga agaagcttat cagatcgcca
    23281 gaaattctat cattgaatta gtcgctcatg cagaaaattt tggcgtaact gttgctgttg
    23341 aagcagggat caatcatcca atctataact atcagttagc taaacgttta atcgatgaag
    23401 tagcttcacc aaatttaaaa atcattttag attgtgcgaa tttgatgcat aaagaaaatc
    23461 atgctgatca ggaaaaagtg atccgaggtg ccttggacaa tttacatggt tatattacag
    23521 cgcttcatct caaagactat atcatggaaa atggaaagat ccgcatggta cctgttggca
    23581 agggctgttt agatttccgc ccggtactgc attatatcaa atatgagcgt cctctaatgt
    23641 acgccactct tgaagctact cctgagattt atgttcctga agcaatagaa cacttgcagt
    23701 ttatttacca agattgttaa ggagaagatt atggaggaac gaatacagaa aagttatcaa
    23761 aaatatcatg caaatgcttt tcagacattg ctgcatcttt atcagggaaa ttattggcgt
    23821 tttgccatgt caggactctt ttttattatc aaacatcttc catcttggtt aatgccgatc
    23881 gctattgcca atgtaatcaa tgcagcttca tcgaaagatt cttctcagtt gcaggccatt
    23941 tatttcaacg cttttttgat ggcttgtctg attggtcaaa atatattgac gaattatttt
    24001 catgtaaaat accatagcac ttcgatccgt caagtagaag ctggactaag agcgaccctt
    24061 atcaagaaaa tccaagaact atctattcct tatcaaaaag aattgcaatc tggacgaatc
    24121 cagtcaaaga tcatccgtga tgtagaagct atccaaacgt tgtcctctca agtatttgtc
    24181 agcggattaa atatcgctgt caatttattc gtagctttag gtatcacgct ttataaaagt
    24241 cctgttgttt tcatgttttt cttattgact gttcctctcg ccgcattcgt tactctcttt
    24301 ttccgtaaaa ggatcagaca gtccaactca gacttcaggc aagaaatgga agagacttct
    24361 gcaaaagtga tcgaagtgat cgaattagca ccgattgctc gagctcatgg gttagaaaaa
    24421 cacgaaacaa ctcgcttaaa taagcatttt actcaaatct atgaaaaagg attccactta
    24481 gatatcctgc aatctgtttt cggatcagtc agctgggcta gttttcagat atttcagctg
    24541 atttgtttga ttttcactgg gatattagct ttacaagggc gcatccaacc cggcgatgtc
    24601 gtgatgtatc agacgtattt cacgacgatc gtcaattccg tttctggaat gatcacgctg
    24661 attcctacga tttcaaaagg catggaatct atcacttcta ttggcgaact gttgattgct
    24721 ggcgatgtag aaacttatca cggtaagaaa aaaatccaac atttggatgg aaattttcgt
    24781 tttgaggatg tttcttttct ttatccggac tcactcaaac cgattatcga tcatttttct
    24841 ctagaggtga aagctggaga aacaattgct tttgttgggc catctggctc tggaaaatct
    24901 acactcctta acttattgat tggatttatc cagccgactt caggaaaaat ttttctagat
    24961 gatcagcctt tggatgaact ggatatgcga agtgtgcgaa attatttagc cgttgttcct
    25021 caaaccactt tgttgttctc cgcttcgatc aaagagaaca tcacttatgg cttgaaaaac
    25081 gtatcaaaag aacgtttaga tgaagtcatc gaagctgcgc aactttcttc actgattgac
    25141 cagcttcctg atggtctgga taccttagta ggcgaacatg gcaacaagct gtctggtggc
    25201 caaaagcaac gtatctccat tgcacgagcg ttgatacgtc agccaaaaat cattttgcta
    25261 gatgaagcaa cctcagcttt agataaccag tcagagaaaa aaatccagca agccctgaat
    25321 tacctgacag aaacacccac tacttttatt gtggctcatc ggctttcaac gatcaaagag
    25381 gcagataaaa tcgttgtgat cgatgaagga aaaatcgttg aaataggtac ttacgaaaaa
    25441 ctgttagctc aaaaaggcta tttctaccgc ttgaaaaatg aatgacaaaa aataggagct
    25501 atgacaagac ttttgtcgta gctcctattt ctgaataaac ggtgttctcc tgccaactcc
    25561 tcggtcacaa gtcacaatag tcatcaaaca tgagaagctg ttttttgaaa ttgttccttg
    25621 taactcagag ttaaacggta ggctcacgac ctcttggtaa atggtgttca agagacagcc
    25681 tatcggcaat aagaagcaat tttgtcatcg ctcaaggccg aacgtctctt tcacaccctc
    25741 tgttgtttca taaaatagtt ttattcgctg taaaggtcgc gaactggtgt catgatgata
    25801 cggttcaagt cattgatgat tgtactgaag ccttgctctt tttgcatcaa gtcattgatt
    25861 acttcttctg attggatttt cacagccatt tcttgtgctt tcattgcatc ttcgtcgctg
    25921 aactcttgtc cactcatttg tttttcttgt aattcgattt gcatcgcttg gaagtctttg
    25981 aacagtttgt gtgcttcttc gtttgcttgt actttctcgt acgcttcttt caacgctttg
    26041 aattctggta attcacggat ctcacgttcg atttgattcg cgctatcgta gatgtttgac
    26101 atgttatgcc ctcttttctt ttagtagtta ctctctattg taacatgggg ttattcgttt
    26161 tcaaaggggc tactctcctt gatatttccg ccagaggtct ttagccgctt caccaattcc
    26221 ctgaacgcct tctttcacca tatcgccgaa gtttttcagc ccttcttttg cttgttcacc
    26281 atattgattc aagttatctt gccaatttcc agactctcca ttagaatttc ctgtgtttcc
    26341 aacttgatct gcagctacca cttgtcctcc tgtggcatag gcatctgcta cactaaatcc
    26401 tgtttttgaa gtatacggaa ggatgccttc tgccgctgat ttgaagactt tcccgacaac
    26461 atttccactt gtcccttcca aatagtgcag cttgctggat tcttcgtaac ccatccatgt
    26521 cgaaatcact acgtctggcg tgtaaccgat catccattgg tcatttgctt ttgtggcatc
    26581 gaaattagtt tctgtggttc ctgttttccc tgctatcgta taacctgcag gattcgcagc
    26641 agccgctgtt ccatttgaaa atgtaccaag aagcatgctg gtcatttcat cggctgtttc
    26701 ctttgatatg acctgttttg gttttttgtt tgtgttatcg acgatcaccg ctccagtcga
    26761 atcaacgatt ttcgtgataa gatgcggcgt atacatctga ccatcattgg caaatgcact
    26821 gtaagcaccc gccatgatca atggagatac tcctttttcc agtccaccaa gggctaagcc
    26881 ataatactta tcagattttg ctaaaggcag gccgaattct tctgctttat catatccttt
    26941 ttgtaaaccg atctcatgca aaagccatac agtaggcaaa ttcaaacttt gtgcaacagc
    27001 ttgatacatc ggtacttctc cttggtatgt cccgtcaaaa ttatgcgcat cgtaataact
    27061 ttgcggttcg tctttcaaga tactggaagg cttgtatcca gcttccagtg ctggtgtata
    27121 tacgcttaat ggtttgatcg ttgatcctgg tgaacgacgc atctgtgtag caaagctgaa
    27181 tcctctaaag acatgatctc ctcttcgtcc tactagtgct tgtacaccac ctgtattcgg
    27241 atctaaagct actgaagcag attggaccat ggcaccatct gaagcatttg ctgggaataa
    27301 tgcactgttt tgataagtag cttctaattg cttttgataa tcctgatcta aagctgtata
    27361 gattttatag cctttattca tgacatcttc ttcatcaaga ccatactcgt taactgcttc
    27421 atcgatcact gcatcaaaat aataaggata acgataacca gaatctgaat tatcgtatgt
    27481 gtcattaaga tacgcgctga tatctgtctg gctttctgct tgttcttgtt cttttgtgat
    27541 ttttccgttt tcttccatta cacttagtac tgtgtttttc cgatcattcg cattttttgg
    27601 gtgatcgatc ggattataaa taccaggacc tttcagcatt cctgccaaag tagcagcctc
    27661 agacagcgta acattcgttg catctactcc aaaatacttt ctggaagcgt cttggacacc
    27721 ccataccccg ttgccaaaat aggcattgtt aagatacatg gtcaagattt cttctttgct
    27781 gtacttcttt tcgatctcga ttgccaaaaa taattccttc gcttttcgat caaacgtttg
    27841 gtctaatgtc agatacgcat ttttggcaag ctgctgagtg atcgtacttc ctccgccccc
    27901 tgatgttccg ccagacaaga ccattcggac tgctgcacgg gcaatccctt tgatatcaaa
    27961 cccgtgatgc tcgtaaaaat tcctatcttc tgtcgagatt actgcatctt ggatataggg
    28021 agaaatcgcg tttaattcta catatgttcc tttttgggcg tacagtgtgc cagcttcttc
    28081 gtttttctta tcataaatga ctgtcgattg gcttaatcct gattttaacg tttcgacatt
    28141 tgcttgtttt gctaaaataa agaggtagat acttgtcact aagacacaga tcaaaccaat
    28201 cagcaaaatc aatttgttca catgatattt tttccagatg cgctttcgcc atcgatggaa
    28261 ttgtccgaga tatggtctga tccaacgcca aaaactgatc aaagcagctt ttatcttttc
    28321 taaaatgctt tgaaaatcca tttgcttctt ctcctgtcta tttgattcaa tcgtcttatt
    28381 ttaccatagt gaaagagtgt tttcttcctg cttaagttgt agttcaatat gtttttttac
    28441 gttagtgcaa gtagagtaac ataagaatga acagaaaaat gtaagttttt tcttaaatat
    28501 gttttaaaaa tggtacaatt agtctgcgat tgcactgaaa ggagtacact tgtgaaaatc
    28561 acgatcactt tacctatgaa ccatcctgaa acaacaattc gcgacttgct tgaaaaggaa
    28621 tggttagttc ctagaaaggt tcgacacttt ttgcgtatac gtaaaaacgt ttggatcaat
    28681 caacaacctg ctttgttcca tcatgaagta aagggcaatg accagatcac attgttattc
    28741 gaagaaacag attataatta tcaagaagtt caattaggag atgcgaagca catccgtgtt
    28801 ttatatgaag atgagcattt gattatagtg gataagcctg caggaatgaa gactcatcca
    28861 aatgaaccga cagaaaacag taccttactc aatcatttag ctgcttatct cgacactaaa
    28921 cagcaacgac cttacgttgt ccaccgcttg gacaaagaaa caagcggtgc cgttttattt
    28981 gcaaaaaatc catttgtctt gccgatactt ggaagaatgt tggaacaaaa aatgatctat
    29041 cggagatatc aagccatcgt atggggagaa attgccaaag atatgaccat caccaataaa
    29101 attggacgag atcgccatga tcggagaaaa agggtcgtag atgataaaaa tggtcagagc
    29161 gccttgacac atgtcactgt caacaaagta ctttctgaac aaacacaagt ctattgtgtt
    29221 ttggaaaccg gacgtacaca ccagatcaga gttcatttag ctcataaggg acatccgatc
    29281 gttggagacc ctctctacca aaatagaaca gctgaacgac tgatgctcca tgcattagaa
    29341 ctgcacatga tccatccatt tactcaagaa aaaatagtcg gtaaagcttt acctggatta
    29401 tgggaataga aataaaaaag aacagagtct tatcagcaga taatgataag actctgttct
    29461 ttttgtgtaa tttgtctgct tacttttgat gttcgtgttc tgctaacagc aaactaccga
    29521 taatcccact ttcattcggc agtccccaac gaacgatata ttcacttact tgaggtgttt
    29581 ccatataacc acccatcaat tcaacaaatt gctgacggat tttttgaagg agatgatcct
    29641 gattcattac cccaccgcct aaaataatct tttcaggtgc taacgtcaac gtatagttga
    29701 tcagtgcttg agcaatataa taagcctgaa tagcccaaac aggatgatct tgcggcagat
    29761 cttgcccttt gatccctgtg cgtgcctcaa tagacggtcc tgctgctaat ccttctaaac
    29821 aatctttatg ataaggacaa gtaccttcat aatggtcatc tggatggcgt ttcacccaaa
    29881 tatgtcccat ttcaggatgt gcgatccctg aaaaaatttc ttcattgatc acgacacctg
    29941 caccgattcc tgttcccacg gtaaggtaaa tacaactatt ttttccttgt gctgctcctt
    30001 gcttcaattc cccatatgca gcagcattga catccgttgt ccaagcagca ggaatattgt
    30061 agcgttcctt gattgtgcca agaaaatcga attgtgccca cccttttttg ggagttgcca
    30121 aaacgtatcc gtaattatct tttgttttgt cgataccaat cgggccgaat gagccaatcc
    30181 cgattccctt caattcataa cgatcaaaaa attcaaatac ctgatccaat gtttcttctg
    30241 gtgttgtggt agggatactt aatttttcta aaatttctcc accatctgaa accgcacaca
    30301 caaattttgt tccgcctgct tctattccgc catacattcg ttttcctcct cgaatccgat
    30361 tgtccgaatc tcataaggtt ggattattgg gacaaccgct tgcttcgttg gttcttcaag
    30421 cagattcaat atgacagttt ttccattgtc tttagttatt tccaattttt ctaaatgact
    30481 agacatattg aaacctctta ctactacttt atcactaaac ttgctgcgtt tcaaagctgt
    30541 aattgcaaac gtttcacttt ttatcgttaa atattgttgt tttgaaatca atgttccttc
    30601 atgatgtttg atttgttgag tggaaaaagg aatctgtgct gcgtatgcat gcaaataagt
    30661 agagaatttt tcttctggtc catgtagttc aatgctgtaa ttgaaccgat gctcacctag
    30721 acactgtgct tctggtgttg gaaaatatcc ccaatcgcct agttctccca cactgcgaag
    30781 tagcgtcact gcgatttgtc cgtcttctgt tacttcatat tcattcaaac caaagtttcc
    30841 gactgttaca ccgtactctt catcatgaat attgacaaat gcttgctgat gttgcggatt
    30901 cgtggggttt tcccaacttt tagacacatg gtttgggcgc ttcaccactt caaaaatact
    30961 atctgcttcg tgatgttcca catgtaactt tgtaggaaac aagacacgta agcgatgatc
    31021 tttcatctga ttgtcgagag tcgtttcaaa gtcgattttt ttactatctt ttctgattgt
    31081 catgattgtt tttatttgaa ggattcgttt ttctttggat cgttctgctt ttcgataacg
    31141 aaattccaca accatctgct gttctttttc taaacgctcg tctgcagaaa cagggatttc
    31201 catttcctgt agaatactta tttttgctat ttccggtgta tctactaata cttttacttc
    31261 agagttttct ttgttactgg ataggattgg ctgatcacag aaaggttgtt taaagatata
    31321 ctcatttcct atatcgccga tatcttcaaa aatatgcaga ttattcaact ttcgtttgtt
    31381 tttgcgatct tccattgtaa tggtaccatt tttttcaatc gtcaaatgta gagggccgtt
    31441 ttcgatgatt cgtccactct gatgaatcat tgtttccttt tcttctgctt tcgcttcccc
    31501 ttctacaagc gcgaatgttt cccaagaaaa tgctggcatg ttttctaatg gtaaagtcac
    31561 tttgatcatt cttgccatat atggcacacg gaaacggtct ttcggcaaat cataaccaaa
    31621 ttggacagtt tcttcagata aaatagctgg tatagtggcc ccactttttg tttctacatg
    31681 atacttacgt ttaggcaaat tttctaactc ttgatatagt tgttcaggta ttccttcagc
    31741 gaatcttttt ctttctaatt cgatggttat ttctgcttca ccagttttat ccattcctgc
    31801 agtatttaca atgacaaatg gaaagctgtc ttttgggaat ccggtcgtat cgattgctgc
    31861 ggtcagctgt tctaaggaat cttgtgcaag atactttcca acttcatctg ctttttcaaa
    31921 acgaggtatc atttcccgat ggacagaatc gactgaacaa ccgcaaatac tgtcgtgagg
    31981 atgattttgc attaatgtct tccaagcata atctaattga tcatggggat agtttccact
    32041 aacttcataa gccatcgtcg caagtggttc tgtaatattt tctagctgtc gctggacctt
    32101 ggtattccat tgttttaagt aaacccgagc agatgctgta ttggctaaag tataccagcc
    32161 atccgtttct tgacttgtca attctccttc tactgagcct aagtcttctg gcacatcttt
    32221 ttgaactgct tccagatagt cagtaaaatt agaatgaata aactcgtaat ctggaaacag
    32281 ttcatttgcg agatggattg cttttgatat atctttttgt accggttgat gatcaacacc
    32341 attcatcatc aataagtggt tcgtagaggc atattgttct gcatccgcta atttttgctt
    32401 ccaaaaggca agagctgctt ctttttctac tggaatctca ttcccgttgc tataccaatt
    32461 ggcaaatagc agaccaaaga ttgctgtttg atcaggtcct ttccaccaca tctctgagta
    32521 ttgggaagaa tagttttctg cttccaaaac ttgattatca aagccaattg gttttacacc
    32581 acggccaaac gctgctgctg aaataccagc ttgtttcatt aattgaggcg tctgtcccat
    32641 atttccaaat gtatcgggaa aatagcctaa catgacaggg gttccccatt tacggctttc
    32701 ttccatgcca atcagcatat ttctcacgtt cgattccgag ctgataagaa aatcatcttg
    32761 caagatataa aatggtccaa ttctcaattt tccttcattg attgcttgtt ggattgcctg
    32821 tcttttttct ggccttactt gaagatagtc atctaaaata atcgtttgcc catccaaatg
    32881 aaaactgttg aaggacggat caacttcaaa tagctctagt agatcgtcta tcaattcaat
    32941 cagtcgcatg tgatgctgtt cgtaagccat gtaccattca cgatcccagt ggctatgaga
    33001 aatgatatat actttctttt tcatttacga tacctcctac ttttctactc taatatcaaa
    33061 gtaatccatg actaattcgc aaaacatcat atttgcccaa gaaaaccatt ctctcgtata
    33121 attttcagga ttgttcacat cgaatccttc gtgcataagg tgtgttcctg cgtcagttgc
    33181 tacaagtaaa ttcaatatcc gctctttttc agatttgtct gacgttgtca ttccttccat
    33241 agctaatgca atcggccaaa cgtatttttc tggcgtatgg gaggatccaa ttccttttgc
    33301 gtactttcct tcatagaaat atggattttc tttactcaac aatgttcttc ttgtttgcag
    33361 ataatcttcc tcttgttcag aacaatatcc caagtaaggt gcggcgatca gattgggcac
    33421 attactgtca tccatgactg tggcgtttcc cattccatct acttcatatg cataaatcgt
    33481 ttgccctttt tgattaaccg ttcgtccgtg attctgaatc ccctcttgga tctctttctt
    33541 caatttctgt gtttgctgta caatttcttt atcatcgagt atcgtttgaa aaatttcttc
    33601 cacataacct aacacgacca ccgcaaacat attggatggt accagatatc cataacggca
    33661 agtatcatcg ctaggacgga aaccagacca tgtcattcct gtaaaagctg tttttgcacc
    33721 tcgcccgtca ttgatcagcg tatcttcttt tcttgtcgtg tctcgtacaa atgtataagg
    33781 agagtgttca tgatcttgct ctgttttgaa cacgtccaag atttttttga taccttcaat
    33841 aaaagattga ttgaattgat cagtttttcc tgtatttttg taaagaagat aggccaactg
    33901 tattgggtag cataaagaat caatttcata ttttctttcc cagatccaat cgttcatttt
    33961 tgtatgatct gtttggtggc cagcaccgtt agcttcttcg ttgaaggcat tcgcatatgg
    34021 atcgatattg atataaaaaa attgcttttt gactaacccg ctgatcatgt cagctaattc
    34081 ctcatcttct tttgcaatca ctaaataagg acgaacttgt gcagtagagt ctcttaacca
    34141 catcgctgga atgtctcccg tcaataaaaa ggtggttccg tcattttgct ttttgactgt
    34201 tgtcaacaga gtattggcaa atgctgctgt aaaattcttt gcccagtccg catggatatc
    34261 cccacatttt tgtgtgatat cttccataaa tttctgcacc gattttggta tatctttata
    34321 agccactaat aaaaccttct ttctatttga tatatcttta aagattatac ttcatacagc
    34381 caattatgtc tacgctttca aaaaatatct ttttatttac tttttcatcc attatggtat
    34441 tatttgaata tgatatatca ttaagaggtg tttatatgaa tcaaccattg taccagacaa
    34501 tatttaatga tttgcaaacg gctattttaa ctggtgaatt acctgtagac agccaactac
    34561 caactgaaaa agaactttca cgtacctata aagtaagcag aatcacttcc aaacgtgcat
    34621 tgactgaatt agagcaatta ggacttattt atcgcgttcg cgggaaaggc agtttcgtta
    34681 aatccgcttc tccggaacag attcttgctt ctcctacaaa aacacgacgg attctgtttc
    34741 ttcttccata tgtcgctgat ttgtctgttg gtgattttag caagggattg aaccctgtga
    34801 tgcaagataa acagattgat gtcatgatga cgacgcttga ctttctacaa aataaaacag
    34861 caaaagagct aatcaatgaa tttgacggat tgatttatta tgctcttgat acagaacaac
    34921 atcttgactt actttttgag ctttcattga aagaattccc tgtcgtcata ttagataaaa
    34981 aaatctatga gttacctttt cctaccgttc tttccgataa tttccaaggc ggtgcgcttg
    35041 ctgcctctta tttgatcgaa cagggacatt caaaaatcgc ttatttgttt ggtacgcaga
    35101 ctcatccaca atccgttcga cagcgttacc ttggttacct tgaagcattg gacaaagctg
    35161 gtttgacttt ccacacttca ctggatgaca aaagcgcgac attagatgaa ttgctttctt
    35221 atatcactaa gtatgaagta actgcttttg tttgtgaaaa cgatgttgtc gctatccaga
    35281 ccatgaatct cttgagacag catggttatc atatccctga agatttttca attatcggat
    35341 ttgatgatat ccaagcagca gctcttgttg acccgccact gacaaccatc gcacaagatt
    35401 ttgaacagtt aggtaagctt gcgggagatg ctttggtcac ttggttagag acaaaagatc
    35461 gaccatccga tagtaaattt ccagtttcat tcatcaaaag acaatcaaca aaggagaaat
    35521 aaaatgaata tcggtcaaat agatactaga catgcaacag cgaatcagcc aaatttctct
    35581 aatgggaact gccagcctta tactggcgtt ccttttggga tgaattattt tgcaccgcaa
    35641 actacggatc aaaacggcag ctggtggttt catcctgatg accgcgtttt tcaaggctac
    35701 cgtcttaccc atcaaccaag tccttggatg ggtgatttca gtcatatgct gtttacgccg
    35761 atcaatggaa aactacagga gaacaccctt ttccatgctc aaagttctta ccgcccagaa
    35821 gaaagtatat tttgcccgac tcatctgtcg atctgtcaat tacgttatgg catctgttct
    35881 acattgatac ctagcatgta tggcggaatc ttatctattg attacagcaa aaatgacagc
    35941 ggtttacttt tatcctttcc gggacgccat cagctctttg ttatagatcc ttacacagtg
    36001 gaaggaaaaa tcacacattt tgctggttca gaagatcctg atttttcttt ttattttata
    36061 ttgagatttg aatatccttt aacaattgat gagttagctg tttccaacaa aaatagcgac
    36121 tcgatcccgt tgtattttga acagacaaaa aaacaaacta tccgatttgg gacatctttt
    36181 atcagctcgg aacaagcagc ttataacctg gaactagaac aaaaccaaag caaagagact
    36241 taccttgctc acagtcaaga acaatggcag tcctattttg atcgtataca gctcacacac
    36301 catgatcaac aacaattgcg gacgttttat cataatttat atcgggtgtt tttatttcca
    36361 caaacatttt atgaaattga tcctagtggg caaaaaatcc actatgatac gactagtcga
    36421 tctataaaac ctggtgttct ctatacaaat aatgggtttt gggatacgta taaaacggtt
    36481 tatcctcttt attctttgat tgctgtagaa aaatacgaag aaatgctgga aggttttttg
    36541 aacagctata gagaaagtgg ctatttgcca aaatggctgt ctcctgatga acgtggactt
    36601 atgcctggga cattgatcga tgcggtcatt gcagatgctg ctgtaaaaga tatccgacga
    36661 gacttgatgc ctgaatttct aacggcaatg gaaaaaggtg ctacggttca aagcaaacat
    36721 ccaaattatg gacgccaagg aacagaagat tacttgacat atggctatgt tcctaatcac
    36781 taccacgaat cagtcaatca cacattagac tatgcttata gcgatttttg tattagccaa
    36841 gttgccaagg tactagaaga agaggaaatg acgaagaaat atcagcagca atcattgaac
    36901 tatcaaaata tctttgacta tgagtcagga tttatgcgtt caaaagataa agatggcaag
    36961 ttcagagaac cattttcagc taatcgttgg ggacaagatt atgcagaagg aagtgcttgg
    37021 caaagcagct ttgctgttta tcacgatttt tcaggactga tcggaaaata tggtggcagt
    37081 gagagatata aagaaaaact cattgagctg tgcaatcagc ccccaacgtt tgacccagga
    37141 ggatatggtt ttgagatcca cgaaatgagt gagatggccg cgatagaatt tggacaatta
    37201 gctatttcaa accagccaag ttttcactat ccttacttgt tcagttatat aggacaacct
    37261 gaaatggcac agccactgct taaacagttg atgactcaga ccttcgacga ttctccaatg
    37321 ggttaccctg gagatgagga caatggaagt atggccgctt ggtatatctt caatagtctg
    37381 ggattttatc ctgtcacgcc tggaaccggt gaatatgtta tcggtatgcc attaattgac
    37441 aaggctgttt tgcttttgtc aaatggaaag gaattgacga ttgaagcaac gcctaatcgg
    37501 ccgcagcaac aatttatcca taaaatcaaa cggatggaca aagaatatac gaaattatat
    37561 tttacccatc aagatttgct gaaaggcggc acgatctctt accaattagg gatcatccct
    37621 caccctaaga aatatcaagc aaaagatttg cctttttcct tatcaaacta taattaacaa
    37681 gaggttgtga aaaagctgtc ctgcatcaag taataagaac agccaagcaa aaatagatcc
    37741 tcatattttt cgtttggttg gtcttattac cgcagatgca agcttttgaa caccgtttat
    37801 tgagaggttg tgaaatcagc gttctgacct gagtattaga gagacaaatg gcaaaatagt
    37861 tcctcatatt ttgccatttt ttgagctaat accgagggtc agctgattga acaccgttta
    37921 gtggagaggt cgtgaaaaag ctgtttagtt tcgagtatta agaaaaattt tgtgaaaatg
    37981 gctttccaca tttttgcata aatttggctt aataccgaga aactggcttt tgaactccgt
    38041 ttatcgagag gtcatgaaaa agctgccttg cctcaagtaa taagaacagc ccaaaattag
    38101 atttctagac aattttttat aagttatttc attacattgg ctttttcttt tatgattctc
    38161 cactgttttc tcggtactct ttaggggatc tgccgacgat tttcttgaat aatttagaga
    38221 aatacgtggt gttgttgtag ccaatctcac ttgctatctc attgatgttt tgattactgt
    38281 gcaaaagcag ttgtttcgct ttttccatac gtaaatggtt caaataagct gaaaaacttt
    38341 ttttcgtttc ttttttgaac agctgtccta gatacatgac atttaaatgc aggttttctg
    38401 acacttcttt gagtgtaagt ggttcttgat aatgctggtg caggattacg attacttttt
    38461 ccacattgtc actgtacttt ttctgtctct gatgcttttt gatgaatgac agaagtagct
    38521 gctgaagttc ttgcaccgtt tttgcctgat ggattttttc gattccttgt aaatattcct
    38581 catcttccag atcaatcaat tcccgttgaa tctccataaa cagtaaaaaa ctggaatatc
    38641 gtatatcttc cggcatcatg gctgctaact gaaactgttc aaaaaaatca gtgatcattt
    38701 tttgagcgac ttccaattgt ttattttgca gcacgcgtct gaaacttgaa aaatcgatgg
    38761 tttgatcttt tgtttctgct tgtactgcgt aaaaaacatg ctcgtcttta tctccataaa
    38821 attgatgcaa ctgtagattg tctttcgctt gttggaatgt ttcagggatt ttgtccaaag
    38881 aatctgtctc ttccccgata ctgatcagcc attcctgatc aggaaagttt tcttgaacaa
    38941 aacaacagaa gccatcaact tcatctgcct ccaacaacaa cgtgatcaat acacggtctc
    39001 cgtaatttcg ttgatagtaa aagatttgtt gccgttcttg caaccatcta ttgataagag
    39061 tatcatgagt tcttgccagt tgaatcaata ctatcctatg ctgcttctca cttatttgtc
    39121 ctattatttc ttcttcactt atttcatcca attcttcatt caaccattga ctgaataaca
    39181 gttcttgata gatttcttgt tgattttttt gttcattttg ctgatctaac cgtgttttga
    39241 ttttcttgag gctttcaacc aattcgaact tattcacggg tttcatcaaa taattcacgg
    39301 cgcctaattg catacctcct ttcaaataat cgaattcttg gtatcctgat aaaatcataa
    39361 attcaaaatt atgacgttct ttttgagccg cttcaataaa ttccagtcca tttatttctg
    39421 gcattgtcac atccgttact actaaatcaa tctgtcgctg ttcaagtaca gctagtcctt
    39481 ctttggcatt ctctgctgtt gctactattt gaaagcctaa actttgccaa tcaattatct
    39541 tttttaaccc attcaaaatc atgtattcat catctaccaa taacacttga tacacgctca
    39601 tccctccttg aatgtaatag aaacggtcag tccacctgtc tcattattct caagcgacat
    39661 ataataactg ctgccgaagc tggcacgtaa acgttcattc acgttttgca gaccgataga
    39721 accgtgaagt tccactttag gatgagacag tttttcttca atctgtttta gccgtttttc
    39781 agtcatccct tttccattat ctttgatgat gatccttacc cgtttgcctt cctgcaagac
    39841 tttgacactt agcgcattat cgaatcgagt aaaatcaata ccgtgtttaa aataattttc
    39901 aactaatggc tggatcacaa atttaggtac ttcgatcttt tccaaatcag gatcgatcat
    39961 aaaatgatag gctactcgat taggataacg catttgatac aaatagacat atttttcgca
    40021 aaagtccagt tcttctttta aagtgatcgt tttctcttga ttcgtattgt ttcgaagcaa
    40081 agcggaaaac gcatacacaa catctgctaa ttcttcactt ccttcgctga ttgcatacat
    40141 tcggatatat tctaatgtat tatataaaaa gtgtggattg atctgtgctt gaagcgcccg
    40201 catatgtgcg tcttgctgtt tgatttctaa tttgtagatg tcttctacaa actgattgat
    40261 gctatccaac atttcgttga taccgattga aagttccttc agttcatatt ccgtgtttgt
    40321 tatgtcgatc cgcgtctcta aattccctgc tgctgtttga tccatggcct gcatgacgat
    40381 agatacttgc tgtgaatatc gtttgaatgt tttataaaga aagataagca gtatattgtc
    40441 taaaataatg ataccaatga tcagcggggc aagatttttt cccgtttcga tttttacact
    40501 ttttttatct agtacagcta atatacgata atcatcagac agttcttggt gttgaacaaa
    40561 attgtttttt tccagatcgt caatcggcaa ttgtgaattt ttcttcagac tctctgtgat
    40621 gatcatttct tgtctttcaa acgtttcttt agctatttta ttatcatgga atgtgtatag
    40681 tcgatttgtc gttccagaaa tcatgtataa agagagtcca ttgaatgacg ttagattttc
    40741 taaaatcata tctagttctt tcttttgaaa accaataaaa atacttcctg actcagctcc
    40801 tccttgtgtg ataggcaact tgatataaaa ggcgtctagt aattttggtg tccccttttt
    40861 tatttcccca cctttgtttt ctctagaaga ttcataatac tccggtagtt gattcaacac
    40921 gatatatatc gcacttagtt cttcataatt tgcgtagaga tctttgattt gatttgggaa
    40981 agaaactaat tcatcggtac tgttttgctg ttcgtataca tacatcagat actgatctat
    41041 gggttttgtt aagtaggtcg tcacattttc gatcttttcg gaattcccta caagctggtt
    41101 tttgatgatc ctactcaagg ttgttttatc attcagcatt ctgcttgtgc tttgaacggc
    41161 atcacttgtc atgttttctg cctgtttttg attttgttcc caagtatgga tactaaaaat
    41221 aacggtagca gtcatcgtta caccgatcat gataaccgcg tatttccgca acagacgatt
    41281 tagtaaggtt ccttttgaaa atagaatccg aaacttattc ataactttcc aactgtttat
    41341 ctaattcttc acgccaatgt gttgtcatcg taccattcca aaccgtcaaa agaccaatga
    41401 caccaaacag gatcaatcct ttgaattgcc aagtcacgcc taaaattata ccgctaccaa
    41461 taattatttt tagaaaagac gaaaagctgg aaaaaaccga aataaaactt agctttagca
    41521 gattaggaac agagatcgta tattcactat ctaaaatcat actgtattga taagtagcaa
    41581 ataggcagag caaggcaaaa agtaaaataa aatcaatagc taaaaaaatg agccctttga
    41641 tttgaacaga taaatataaa ttgtaactca ataaagcagt accagataaa aataaactaa
    41701 atagcagatt gcctcttaaa aaatttcttt tatatatatt ccagcctctt tttattgtga
    41761 tttctttata ctcgaatccg tacaaataaa atagttcatt gactgttttc catgccgcac
    41821 ctaatccaaa gatgatcccg ccggcaaatg tatatatcca gaaatacaag gttagtttta
    41881 taatgaccca gatccggata aataactctt ccaaaacctt ccctaacata tcttctcctc
    41941 caaacattaa gtttatactt tctcattata caaaaaaagg ttgggcaatc agcaccttga
    42001 cctgattatt agagaaacaa acggaaaaat agttcctcat attttgtcgt tttgtgagcg
    42061 aataccgagg gttagctgat tgaacaccgt ttaccaagag tttgtgaaat agccgcttag
    42121 tttcgagtag taagaaaaat tttgtgaata tggctttcca catttttaca tatatttagc
    42181 ttaataccga gaaactggct tttgaacacc gtttattcgg aacaagaggt tgtgacacgt
    42241 cttttgtcac aacccctttg tctttattca ttattattct tgtcggaact catcatattg
    42301 tttttgcatt tctttcaata ccttatcata gccagccttg tccaaagcgt ctttcaattt
    42361 cggtaatgtt tcatctggat caacagtccc tgtattcaat ccatctaaat attgattcat
    42421 gacattagaa atattactta attctgtttt gacactgtca gtgttgaagc tgaatcctaa
    42481 aatcggtgaa gtttctgcat cagcaatcga ttgatcacgt ttggcaatca tgtcatccgt
    42541 aatagactct tgtgtatata gaatcttgtt gtttcctgta ttccaagcag acatatgtgt
    42601 atttggctga taaccatcta gcaatttgat tttatcatct gaaccatcga ctttttccca
    42661 tgcttctccc tcgatccccc aaacaagccc attcaataat tctggatcac tgttaagcag
    42721 ccctagaagt tctactgatt tttctttatt ttttgaagta tttgatacga caaaatttgc
    42781 catttgtgct tgagctgtag attttagtgg aacagtaatt gcttttgaga caagttcttg
    42841 ttttgctgca tttgtcaaaa ttgtatcgcc ataatcatac ggtccttgtg tttctccacg
    42901 cattagccaa gtatttcctt ctagtggata atccttattg ctcgttgcag cgtcacttgg
    42961 aatgagtcct tgtttgtacc agctatgcat tgtacgtaac agtccgatat acgtttcatt
    43021 atcgtattgg ttgatgattt tcgaatcatc tccatccaga tcaatagcaa atggtaacgt
    43081 attccctaaa ggataatcaa agttcccttg gactttgaag ccttgtccaa tggcaaaagc
    43141 tgccgtgttt ggttcttttt catggaattc cttcaagact ttttctgcat cagcgtaaga
    43201 ttggattcca tcaattgaaa gatcgtattt atctagtaaa gctttgttaa aagtaagtac
    43261 ttgttgagca aagacatttc cattgactgg gaaagcatat aattttccat tgaccagatt
    43321 tcctttaata tatgcttcat ctaaatcatt ataagctttt tcagcgtact taggcgctaa
    43381 ttcagtcaaa tcagcaaagg ctcctttttg ggcattggaa acatagttgt tcgcaaaggc
    43441 gatatcataa ttttccccgg aagaaatgat gacgttcatt ttcttttcgt aatcgcccca
    43501 gccaatgtaa ttgatattga cttttacacc gatctctttt tcgattcgtt tgtttgctac
    43561 ttccatcaat tgatcgaaat tatctggttt atctccgatt tgatacatct gcaaagtgtc
    43621 cgaattgcta gcttctgcct ggtctttaga accagaacct ccgcatgctg ctaatgttcc
    43681 caacaacaac gctgaaacac ctgtaaaggc tagtttcttc cataacttca tttttcttcc
    43741 tcctaatttt atgatttata tttttgtttc tttattcttt tactccgccg attgttagac
    43801 ctttgacaaa atgcttctgg aaaaatggat agctgatcgc aataggcaac gtcgagatga
    43861 ctacgatcgc cattctggca gattctcctg gaactgaggc taatccgcct gtcaattggc
    43921 ttcctgctcc tgaattttgt gtcagatatt gaatattact ttggattttc atcaaaagat
    43981 actgtagtgg aactagctta tcatcttgga tgtatagtaa agcattgaac cagtcattcc
    44041 agtaacccaa tgcggcaaat aaactgattg tcgcaatacc tggaacagct aacggtaaaa
    44101 cgatctgaac aaatattcgc agttcgctag ctccatcgat ccgtgccgat tcaataatcg
    44161 aatcagagac cgaacgttta aagaatgtgc gcatcacaat aatattgaag ggactgacag
    44221 ccattggcaa gatcaatgcc caaatcgtat cttttaactg aagaagattt gtcataacaa
    44281 gataattggc caccatccct ggtgagaaca acatcgtaat caaacaaaaa acggtaaaaa
    44341 aacgacggaa tggaaagttt gaccgtgaaa tcgcataagc atataaagaa gtagccgtgc
    44401 tattgatcag tgtacctaaa acagtaacaa gtacagtgac gaaaagcgct tggaaaattt
    44461 tatcctgcat ctggtcgaac aagtacgtat aaccaaatat actgaacttt tctggccaaa
    44521 aactgtaccc gtgagtcgac aatatggact catcggtaaa agagatggcg ataacaaata
    44581 taaatggcaa aatacaggaa atagcaaaga gtgcaatcat tatattagag aaaaaattag
    44641 ccgtcttatt gaaagagcgg acttggactc tctccacttt cttttttttc atttttttcc
    44701 tccttagaat aatgcagaat cgctatcaaa acgtcgggcg atcgtatttg tgatcatcaa
    44761 caagacaaag ccgacaactg attggtaaag tcctgcagca gccgtcatac caaaatctcc
    44821 tgtggatgtc aggccattgt agatatacgt atccaaaact tgagtcacat catataatgc
    44881 accggaattc ctaggaatgt tataaaacag gccaaaatca gctcggaaaa tgtttcctac
    44941 ggctaaaatc gttaaaatcg tcattagtgg aataagttgt ggtatcgtca catgtttgat
    45001 ctgctgccat ttgctagctc catcaaccat agcagcttca taataagtcg gatcgattcc
    45061 cataacagat gcaaagtaaa taatgctgtt ataaccaatc cctttccatg taccaatgaa
    45121 caccaagata aacggccaat atttcggttc attataccaa ttgacagctt ctcctccatg
    45181 tccagtgatc cactgattga atattccttt gtcaggactt aaaaaagcgt aaacaaagta
    45241 actgataatg acccaagata gaaaataagg tagtaaggac atcgtttgat aaactttaac
    45301 gagtcgttta tttctcaact cgctcataat gattgcaaat acgactgaga tcagcagatt
    45361 caaaaggata aatgctacat tatataaaat tgtattttta gtgatgagaa atgcttgatc
    45421 cgaagaaaat aaaaatttga aattttccca acccacccaa ggactttccc tcaagctagc
    45481 caagaaccca tctgctgaaa tatgaaaatt tttgaatgct acgacattcg ccattacagg
    45541 tatgtaaaag aaaaaaatca tccaaagcat acccggtaca gccatcagga caagtgcttt
    45601 ataacgccat agattcataa aaaaatgatt gaaccccttt cgttttttca tctaaaaacc
    45661 cctttcgatt cattcgcaac gtaattatag cgctttcaat aatgagaata aataaacaaa
    45721 gtatagggaa aatgaaacaa agtataggag aggttgtgaa atcagcgttt tggcctgagt
    45781 attagagaaa aaaacgggaa aatagttcct catattttgc cgttttttga gctaataccg
    45841 agggtcagct gattgaacac cgtttatcag aggttgtgaa ttcagcgttt tggcctgagt
    45901 attagggaga tcgtgtcctt actatctaac tctgagtcac aaggaacaat ggggactgta
    45961 acaaaagtct tgtcacagtc ccttattccg aacaaacggt gttccagaag tagcttctac
    46021 ggaaataagc cgaaatttca caaaaaagcc atccgaaagt cagacggaca agtctgcttt
    46081 tcagatggcg ctacaactac tctgcttatt cttttagcta tccattcaat tatttttctc
    46141 tcacttgttc tagctcttct ttggtcatgg gtcgatattg ccctttattc aaatctttag
    46201 gcagccaaaa ttttcccata cggattcttt ttaaatataa gacttctttt cctactgctt
    46261 tgaccattcg cttaacttgg tgaaactttc cttcatgcaa aatcagacgg ataattgaag
    46321 tttctgtctc ttgatctact tgatcaattt ggagttttgc cggcaatgtc tgctcatcgc
    46381 catcaataat cagtccttct gcaaataaac ggatatcttc ttctgtcatt ataccgctaa
    46441 cctcagctag atattctttc tccacatgtt ttttaggtga tagtaactga tgggcaaaca
    46501 ccccgtcatt cgttaaaatc aagaggccct ctgtgtcttt atctaatcgg ccgactggaa
    46561 aaagatcttc ccgataatcc tggtcttcca ataaatcgat tacggtttga tcatgattat
    46621 cctgagtagc agaaatgact cctgcaggtt tatgcaaaat gtagtaaaaa tctttttgat
    46681 acgtaatgat ttctcctaaa taagtaaccg catcttcgaa ttcatttact tgcgctttat
    46741 cgcttttcac cacttgtcca ttgacttcga tcgttccttt tttgattaat cctttgactt
    46801 ctttgcggct gccaagtccc atatctgcta aaaacttatc taaacgcatg cgtttccccc
    46861 atttcaaaag agcatcaatc tagctcttct gattcactta ttttattttt aatttatgtc
    46921 gtaaacgcgc tattcctggt cctagtagtc tttctgccaa gcggattttc aaagctaaat
    46981 aaccatacac taaagcccct atacctgcta ctacaagaat caacaataga gactggaatt
    47041 tgctatcttc gtttaaaaaa gcaccaaaaa tcatctttgt gatccacgaa gccaaaagca
    47101 taatcaaggt aagaataaag atcagcaatg tcctgcgcca gacaaaactt ggtttaaagc
    47161 gggctacttc atggattctc tttaagatca aggtacaaga cacagcaaat ccgatcattg
    47221 tcgccaataa agggccgtat acttcaaata aacgaatggc tgggtattga agaaggagtt
    47281 tcactagaaa cccaataacc aaataattaa ttgccgcctt gttttcaaac attccttgca
    47341 gcatgttgga aactagcata tatagtccta ggaagagtcc tacaaaactt gcttggatca
    47401 gtacattact tcctagagaa tccggtgtat aaaataatgt atttagcgga taggcaagta
    47461 acataacacc aaatgtcgcc ggaaacataa aaaatgaaaa caactgtaaa tttccgcttg
    47521 tcaattttgc cagacctact cgatctttca acgtaacagc ttctgtaatc aacggtaacc
    47581 cagtagacgc gatcgatgtt gccaatgcaa taactaccat cgtcaactta tctggattgg
    47641 cactaaaaat cgaaaaaaga tccagtaact gtgcattgga atactcggtg gatgcagaca
    47701 tgatcttcat aaaagtgaac tgatcgacta atttgaagat cgttacccct gaacccacaa
    47761 taataaacgg aatcgcttct ttaacggtat ctaacaacaa ttccttcgtt gcaatattta
    47821 ttttgttttc gctgtagtga ataaacgccg atgtatacgc ttgatgtttc ttcaaaaaat
    47881 acaaaaggac aagaatactt gctagcatac cgataaatgc cgcgaaagtt gattgcgtga
    47941 ccgccgtcac atagtcacca tccatgactt tcatgatgat gaatgtagcc aatagcatat
    48001 aaaaaatacg tgccacctgt tctacaatct gcgacagcgc ataaggcatc atttcttgat
    48061 tgccttgcaa ataccctcgt atcacactca tacaaggaaa aaccaataca gcgatactca
    48121 aagaacgcat cgttggaatc agttcttctc cgccaccaga agcatgagct agccaaggag
    48181 aggcgatgta catgaacaaa gcaaacaaca ggcctaaccc gcccatcatc tgtaatgcac
    48241 ggataaataa tcgtcgtgaa gtgccatatt cattcaatga attatagcgt gcagtttgtt
    48301 ttgcaatcgc agcaggtatt cctgctgtag agatcagtag aaacaatgca tatatattgt
    48361 atcccatatt gaataatcca ttggcagcct tagcattttc gcccatccaa gcataccagg
    48421 gaatgatata gacagcgcct agcaatcttg aaatgatatt actggcggtc atccaagcag
    48481 agcctcgtgc cattttttct tgcggtgtta attgatctaa tgctggtttt ctttgattat
    48541 ccatcggtca gattccaact ttctacaaaa cattactatc attttaattg gtaaaacaga
    48601 aactggcaat cgattttata taacttttat aagaacaatt gtttttttga attcggtttc
    48661 gtttttttgg taaagtaaag aaatatacag ccttttatgg ctaacattta taggagatat
    48721 caatgacaca agaaataaaa aaactacccg ttatattttt aggtcttttc tttatcacag
    48781 ttggattgaa ttggttcttg ctccctcacg atatagcttc cgccggagtg ggcgccatcg
    48841 gacatttagt tgaaacggcc ttttctatcc aacgctcagt tactgtttgg agcatcaatc
    48901 ttatgatgct gcttctagcc gctgtcctat taggaaaatc agtatttttt aagactgtag
    48961 cgggaagtct gctttttcct gttgttttag agattgttcc aaaagtggaa atgatctcct
    49021 cacatttctt ttcactgatt tcaggaagtc ttttgttcag tcttggggtt tacacattgt
    49081 acacagtcgg ggcctcaaat ggcggtataa cgataccgcc gattattttc cacaaatttt
    49141 ttcggcttcc aatgccgcaa ggacttttac ttaccaatag tcttatcgtc tttttgaatt
    49201 attatgtttt tggattgttg gagacactat tcgttctcct atctattaca gtcagttcat
    49261 tgtttatgaa aatactcatc cgcttgtccc ctgtgtcaag aaaatttgaa taaagctgga
    49321 ttttgtcata gcggaaacaa acgatatatt aaaaagagtg tgctataata aaccaagaaa
    49381 ttgaataaag cgagggatca atcaatgagc ttctctttag aagacatccg tcatttacta
    49441 ttaaaagaaa atctattaaa agaatttgtt tcaacaagag gctggcatct tgatgtacca
    49501 gaaaaagctg aatttcttca gttaagttat gattcaagaa aagctgatgc ttctactttg
    49561 tttttctgta aaggaatgaa tttcaaagaa gaatatttgg attcagcaat cgaacagggt
    49621 attcaatatt atgtatcaga acaaccatac gaaaattcag cagtaggaat catcgtaacg
    49681 gatatccgta aagcaatggc gcttcttgct atggcttttt acgactatcc gcaaaataaa
    49741 ttgaaagtga tcggattcac tggaacaaaa ggtaaaacaa ctgctgcgta ctttacaaaa
    49801 gcaatcttgg atcacacaac aaataaaaaa acagcattgc tttctactat gaatacaacg
    49861 ttagatggca aaacatattt caaatcccat ttgacaacgc ctgagtcatt agatttatat
    49921 cgtatgatgt cagaagcagt tgaaaatggt atgactcatc tagtgatgga agtttcttca
    49981 caagcttaca aaacacaacg cgtatacggc ttgactttag atgtcggaat cttcttgaat
    50041 atctcgcctg accatatcag tccgatcgaa catccgacat ttgatgacta tttctattgc
    50101 aagcgacaat tgatcttgaa ttcaaaaaca gttgttttaa atcatgaaag tgactatttt
    50161 gatttactta gggaaacagc cgatctattc cagattccaa cgatcactta tggtcgttcg
    50221 gaagaaagca attatcaagt gatccgttca gataaaggta ctcacggttt tactttatct
    50281 tctcatgaag atcgcttagc tatctgcgat actgcttatg atattttgct ggctggagga
    50341 ttcaaccaag aaaatgcagc cagtgcgatc attgccgcag cactaacagg tgcctccagt
    50401 caagatgcac aagacggatt aaaagaagct cgtgtaccag gccgaatgga tcaattgatc
    50461 caatccaatg gagcgcatgt ctatgtggac tatgcacata attatctaag cttgaaaaca
    50521 ttgctgaaat ttgccaaaaa tgaacatcca gatggccgtg taattgttgt attaggcagc
    50581 ccaggaaaca aagcaatctc ccgtcgacat gattttggaa aagtgctatc agaaacagct
    50641 gacatcgcct ttttgacggc agatgaccca gcatttgaag atccgaaaaa aatcgcggaa
    50701 gaaatcaatg aagcaattac taatccagat ttgatcgttc attatgaaat ggatcgtcct
    50761 gaagcgattc gacgcgcttt agcagaaagc gctccgcaag attcagtcgt tattgcggga
    50821 aaaggcgtgg atccctatca aaaaatcaat ggtgtagatg aaccttatga aggggattat
    50881 gcaatcgtga agcggttgat tgaagaataa tggtatttat atactagtgg tttcccattt
    50941 ctaagaaaaa aagggactgt gattttttgt cacagttcct tttttcttag aaatcatttt
    51001 aacttttcac tagctaattc tgctgccttt tctctttctt catttaataa tttattatca
    51061 tagaatttga taaatgggaa ccagataatg aatgcgatga ttgcacaaat gactgctaac
    51121 acagcagctt tccaatcacc accactacca acaaatgctc cgatcccgac tggtgaaggc
    51181 cacggcatct gtgcaagcat cggtttgacg atttccagcc gaatggcaaa ataagcgagt
    51241 gtagcagaag ccatcggagc taagaaaaac ggaaccgcta aatagggatt gtagacgatt
    51301 ggcatcccga aaatgattgg ttcattgata ttgaataatc ctggtacaag tgaggctttt
    51361 cctaacactt tcagctgatc agatttcgcg aggaatgcaa taaagatgat caatcctaaa
    51421 gtcgcacctg atccaccaac ggttacataa gaattgttga attctcctgc caacggataa
    51481 tttgcgcctt gtgcgttagc tgccatatta gctaatacga tcggggtcaa gaaagaagtg
    51541 atgatattcg ctccatggat ccctacgatc cacaatgcat ggatcaagaa ataaatcacc
    51601 atgacaccaa gccatgtatt cgtcaactgc gtaacaaacc caaatgggat agcaatcatt
    51661 ttgaagatat ccgttcctag tgcaactaat aatccattga tgatcatcac cacaaacgca
    51721 atgacaaatg ttgggatcag agcagtgaaa gaacgagaaa ctcctggcgg aacaacatct
    51781 ggcattttta tgacccaatt tctcttgaca cacatacaat acaattcgac cgcaataatc
    51841 gacataataa tagctgtaaa gattcctgaa gttcctaaac gttcgacaaa agagcccatc
    51901 ctaataccat ttactacagt ttctgtctca ttgatagaag caatcaagct gattttacca
    51961 tcagtcatga tcaattcagg gatacacata aagaatgcaa aaacagatag taatgccccc
    52021 gtgagcggat taacatttaa tttttgttca tctcgttcaa ttgacgttaa ttcataagca
    52081 aacacaatgg caaagtaaat agataaaatc cccatcgtca ttgtattgac gatcatgtac
    52141 aagtcactaa ctttgaaaaa agttgcatta aaaaatcctt ctaaaaatgg gaacggtaat
    52201 ggcaaaatat ttaaaaccaa aaacatcgag cctacaatcg tgaaaggaat agaagccatc
    52261 cccgctgcca tgacagcccg aacgatttta agttgcgcaa ttttccccat aggtcccatc
    52321 aggtatttct gcaaaaaatc aaacattagt tattctcctt tcctaaatat aacgcttttt
    52381 catattgttt aatacggata tactgttggt cttggttgag tgaaattttc tttaaacgat
    52441 actgtataaa tgcactggca aaaataccgc ttacaacaag aatgaaaaca aataactgtc
    52501 ctccattgtt atttgccata aaaggataca agaatgtaaa tcctgaggta aacaacactg
    52561 gaatcactaa taaattaaag acactctgga acaaaaaata ccactttgtc catggaacgt
    52621 tcgtttggtg ttttcgataa agctttactt gttctcctac tgcaggcaaa atagctaaaa
    52681 tcagaatcat cggtaaacta cttcctaaac ttttagctga tagaagcaga atcatccatt
    52741 gcatgttcat gaaaaagaaa aaggcagtca ggtaacgtac gattagataa cgattgaaat
    52801 acatgttttt caaactaagt tgcttttttt ctaattcgat tttccttttt actgtatcct
    52861 gcacaatgat ccttcctttc tatttatttt tttgatacaa ataattcatt tcctgtgcaa
    52921 cttccaataa tgtcatcgtc gtcatcagat gatcttgtgc atggaccatg ataatttcca
    52981 tttctatttt tgtcccgctg gcatattctt tcagaagttg agtttgtgac tgatgcgcat
    53041 gaagaatctc ttcatttgct tgtcgcaact tctcttctac ttcttcaaac atctctttac
    53101 gcatcgagcg aaatgcttca tgtatcagtg tccgtgcatt tccgctatgg aaaatgatat
    53161 caaaagaagt cacttgtagt gtttcactgt ttattttttc agccatctgt tttcctcctt
    53221 attcgatcag tttgataaat ttactgctga aattctcaaa aataggttca gctaagattt
    53281 cctgctgtac ttttagctgg tcaactaacc taacgattgc tttagtcacg accgtaattc
    53341 cttcattttc gacataagaa ggcgaaacta aaaaaacaaa atgaatttct tgatattgat
    53401 cccactgcat cccagaagga atcaatgcaa cggctacctt tgtttcgatt ccaactggaa
    53461 cagcgggatg tgggactgcc actgtatcac tgaatatgat ttgtcccata ttttcacgtt
    53521 gctggatctg ctttcgcatt tctcttatat atccttcttc ttcatttatg ctcagctttt
    53581 gcagcaaatc atgaagaatt tcttcctttt tcggttcgta cgtataagtc ttgaaaaatt
    53641 tttcagacaa ctgttcggtg taaatctgct ttttttgctg tagagaaaat gctggtatcg
    53701 gtctatctga ggaatgatag ggtatagatt ctccaactac ctttcgtatt ttacgaacat
    53761 catcttcatt caaaaaaata ctgacatgta aaactggaat tttgaaaaac attgtcgaaa
    53821 gatcaataga agaaataatc aggtcgattc cttttaaagt tgtttcattg atctcataat
    53881 agccttttac acttaccact gtaatatttt taccgaattc actgactacg cgattcttta
    53941 atagttgggc actgccgtaa cccgttgcac agataatcaa tgcatgtagt ttatgcgcag
    54001 ctctttcttt ttccaatgcc gccatgagat gcaaagccaa ataggcccat tcatcttcat
    54061 tgatggtata gtttttcaaa gccggcatgt tgctgaaatg cctttttact gcgtcaaaga
    54121 ctttgggatt ttctttcttt atctcctcag tcaatgggtt ctcaatgcga atacctcggc
    54181 tcaatcgaat catcatcggt gacaaatgat cgagtagtcc attgaaaagc tggagatcct
    54241 ctactaatga aaaatgaaat tcctgagaca atcttttcag aactttcgct aattcctttg
    54301 atagttcctg atcattttga ttttctttgt gattcgactt agccatgaga tgtaatgtca
    54361 aataagcaat ttcttcttcg ggaaacgata cacctgcgat tacctcaata cgttgaacga
    54421 tccgctgcgc cacttgatac tctactcgct tagaaacttc ttgttcgatg cctaattcct
    54481 tgatttcaaa cccttctcgg agccgtttga tccccaaagc caagtgtaaa gtcagattct
    54541 gtatgataaa atccgaaact tttaacttag cttctcttgt ttcatcgaga atgataatga
    54601 ctagctcttc aaaactgatg tctgggaaaa aacggctttg ccctaaatat tctttcaatg
    54661 aatttccata atggtttcca aaaaaagtat ccatgataaa atgccgtcga tttctttctt
    54721 ccccttcgat ccatgtccct tgaccatgct tagaaacgat ttttagtgaa tatggaatca
    54781 atcgctcctt gatttcttgc atgtcctttg tcaaactgga acgactgata taaagctctt
    54841 ctgccaaatc atccataaaa agaatggcat cttccaaaag caattggttc aatatatact
    54901 tttgtcgatc ttcggactca taaaatcctt gcggttctct agcatatcca ggtactattt
    54961 cttgccgact caaaaacaag tcaaatgtca gtctttgtaa aatatgcagt tggtagccat
    55021 aacctggttt agcaatgatc ttacctccgt ttttttctac taactctttg atccgctgca
    55081 agtaattacg gattgtccga tcagataata acaattcaga agctaaacgt tgactggtga
    55141 catactcctt cttgtgatca atcaaatatc tcaacagcaa tttttccttc tgtttcatta
    55201 tcatccactc ctattccatc atatgttctc ttcgatcacc tctgctaact tctggatgcc
    55261 tgtagggatt gggacatacg cttggaaagg gatactaaca acaggctttc caacagattc
    55321 tcctaatttt ttgaatttat ccaaaaacat cgtcgtttgc gggctgatca gaaataaatc
    55381 aaaatcacta ttcttaatca tattatcgcc ttctgtagct gaaactgcat ctacgagtac
    55441 ctcttctctt ttttgcttaa agaaatccgt tgtctttgag gccatcatcg aggatgacat
    55501 tcctgccgca caaataatca atgctttttt cataaatcaa tcactccttt tatttttata
    55561 aaccaagcat atcttgtaag cgttttctat tcaaaatata tatttccgta gcattgcgga
    55621 aaaaatgtgt atcatatctt gaataataat ttctggcacc gtgatatact agtgatagaa
    55681 ttttttcagg aggggattta gtgagtatca cagtgaatat tttgtataca agtacaaatg
    55741 gacaagccag aaaatttgca gaagaaatgg tcgaaagaaa cattgtcaaa gcgattcgtg
    55801 cagaagaagg aaacgagaaa tatgactatt actttccact agaagatcca gaatctcttt
    55861 tactgatcga ccgttggaaa gatgaagaag caatcgaaaa gcatcacaaa tccgaaatga
    55921 tggctcaaat aaacgaactc cgtaaaaagt ataaattaaa aatgaaagtc gaacgtttca
    55981 ctgatttacc gtaaaaagat acacatggaa tgatagcaat ttatcatcca tgtgtatctt
    56041 cactttttcc ttatttttta ttcgatctca tctaatgatt caaaccgtgt ttttctctta
    56101 tttttcggat aagtatttca gtcaccccaa tatacatgat tcctaaacat accccaagga
    56161 tattctcaaa aatgcggatc gttactgctc ctggaacccc gaataaactg gcagtgattg
    56221 ccaaagcacc aaaagaatta aaaactgttt tatatctata ggtagaacaa acacctaaag
    56281 ctagaccacc taatataccg acccagttaa aaggaataaa ttggctgata ccaataaata
    56341 aaacacatcc aatcaatgag ccaatgattc ggtctactgc tcgttctttg aaaccaatcg
    56401 acatcaatcc atagctagat acaatagaag aaaatgcaaa ccctgcccac atcaatcgct
    56461 gaaaagggac atactctcct gcaacgatca aaagactaat gccaaatgca tagatgagca
    56521 tccaaatttt ttcctgcgaa tacatgcctt tcaaaaaaat ctctttaaac aagcttttgt
    56581 ctttgttctt ttctcgatgt tttctgtaaa ggagaactga aaaccaacaa aaaaacaaaa
    56641 ataataagct acttgtttgt gtaaagaaat tcttgttcaa cgaatcttta ggtaacgaat
    56701 aaacaataaa gagatatgaa aagccgtaca aagaagcatt ccccattttg ggatcactag
    56761 cggttgccat taatatgctg cttagtaaaa taaaatgaat caacatgccc ataactgacc
    56821 atttgatcag ctggacatac ggtgctacta atagtgagaa catgacgatt gctaaaccta
    56881 tgatcgaatg ggaaatctta taaccaaagt caacaaaacg aatactcatc aacatacaga
    56941 ataaaaccac agcgtatggt ttatgcttcg attcaaataa tgttgtaatt ataatgataa
    57001 aacaaatggc aaacaatacg atgaataatg atcgtaaaaa caatgaacaa atatacatgc
    57061 acttttcttt tttagaagct gcttctcgta ttttttgttt taaaataaac ggatctagtt
    57121 gtagagactg ataaaaatcc acctgttgtc gtcctttctt tttactttta ttttttacag
    57181 tcatctatga caggttgtaa atactatgga acatcatatg gcgttgtcat tttcttgtca
    57241 actatttttc ctattcatgt ttttataaaa aaacatatcg ttttcttgta tgattaaatc
    57301 accacaaaat aaacaactga gagaacgata tgctttatga atggttctat caaaaaaatt
    57361 ctgagatcaa tagacaaaaa tttgatgatt acagaggtct cttacgaaac cttacagaag
    57421 aaaaaaacat tgatcgttgc tgcagttctc ttccctgctc catgtgtctg tagaaattgt
    57481 ggttctgctg tggtagatgg aaataggaaa ttaatggtgg tgaaaaacaa gaagaaggaa
    57541 accattgtcc actttgaata atataatcat atgccaatgg ttatacgcct aaaaaagcag
    57601 cgctatacct gtaaaaactg tcgaagccat tggaacgctc aaagttattt tatccgtcca
    57661 aggcactcga tttcaaatca tgtcagacat aaaatcactt ctttactgac tgaaaaagtg
    57721 tcgttatttt ttatttcgaa aagttgttag gtatctttga caaccgttat tcgcacattg
    57781 aaagagttga gaagctattt accaaagtct tccaaaagaa ttctgtcttg agtgttgagg
    57841 gttgtgaatt tcgttctcac gtttccgttg aggataaact gagttttatt tccgcggatg
    57901 gcgagacaga aaaattaatc gagaaaattt acctacacaa aaaattcctc gattaacaaa
    57961 ctatttcctt agctgcacta atcctaaaga aatagaattc ttagttacag acatgaacgc
    58021 cacctacttt cagctcacca aacatgttct accaaatgcg aaattggtga ttgatcgatt
    58081 acttggtttt tccacgcctt tcaaggaggc gtaaccttta ttcacgagtt ggttgaagct
    58141 ttccgagaca aaagacccga cttgtttttc tccttattga caaagagcca ttaaaactag
    58201 agaaaaaatt acaactgatc gctgattatt tgtagaaaga aaatcaaagt attacccaat
    58261 aaacttgagt cattaggcaa aaaacactgc gaaactcaag aatgattttc gcagtgtttt
    58321 tgtatatttt ttattaacta gtattactac aaaggtttat ttttcacttc tcaacgcagc
    58381 acaaaattgt ctttacttat ttactggttg ggttcaacct tctctactcc gatactaata
    58441 tttgtttgta taccccttct aaaatcggta gtttccattc aattgatggg tactagttga
    58501 ttttaaaaac tatgcttatt caatttttta ttttagctca tatatttcgt ttctttctaa
    58561 attttatact gatgaaaaca agtagcacac ccaatattga caatataaac tggctaatga
    58621 tggtttctcc agtttttgga agatgcttat ttccactgct tgttggattg tttcctctta
    58681 tatctgagct atcagcaact tttctattct cttttgttaa aaagatcgcc acttcttgtt
    58741 ctttttcgat cttgaaagtt actggtgtcg catccaattc ataccccgtt ggcgcttgag
    58801 tttctaccag ctgatatgct cctggtgcta agccatctat cgccagtttt ccatctgctc
    58861 ctgtggttag acctgactgc agaacggttc cattggcatc ttgtaactca aaaacagctc
    58921 cttgcaggac ttctccgctt tggtcatcga tctttgtcaa cacgacaccg cctggtgtaa
    58981 gtcgattttc tttcgtcaat tctaccaccg ctgtctgact tctttc
//
LOCUS       DAZKKZ010000009        58727 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.009, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000009 DAZKKZ010000000
VERSION     DAZKKZ010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 58727)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 58727)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..58727
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.009"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            137..1654
                     /locus_tag="ACG8LA_000597"
     CDS             137..1654
                     /locus_tag="ACG8LA_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HFQ0202925.1"
                     /translation="MEATMLISSVKRVGKVDPRLYSSFIEHMGRAVYEGIYQPDHPSA
                     NKSGFRQDVIHLVKELNIPMIRYPGGNFVSGFRWEDSIGPIANRPRRLDLAWRTIETN
                     EVGIHEFYNWCQHVGAEINMAVNLGTRGVDAARNLVEYCNFPKGTYWSDLRRSNGQES
                     PFGIKTWCLGNEMDGPWQIGHKTAEEYGRLAEETAKAMKLVDDSIEVVLCGSSNRQMP
                     TFGDWELTVLDQAYDQIDYLSLHQYYGNQKNDLSHYLARSLDMDRFISEVTAMCDTVK
                     AKKHSKKQINLSFDEWNIWYHSAEQDEQAAPWQIAPPLLEDNYNFEDALLLGCLLITL
                     LKHADRVKIACLAQLVNVIAPIRTETNGEAWRQTIYYPFMQAAVYGQGEVLSPQIRSA
                     NYATEDFEEVPYLESIAVINDKELVIFAVNRGEEEMNLTVHLSELSLEGVIDFSEMSG
                     FDTKATNLPKSEQVKPSHSTNVKAEDGKINCLLKPLSWNVVRCRLSDEGGTKNER"
     gene            1626..2915
                     /locus_tag="ACG8LA_000598"
     CDS             1626..2915
                     /locus_tag="ACG8LA_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFQ0202926.1"
                     /translation="MKEEQKMKGKKWLIGSLLVAATGILGACGGGSSAESDSDKEVTL
                     TFWNGFTASDGEILQEIVNEFNKTNDKNIKIEMDIMTWANLNEKLPTAISSKKAPDFI
                     ALNYPDFAQYVENGAVQPLDDFWEYDGVDKSDFKETAIELGEVEGKQYFVPMQVQGMY
                     MYWNNDLFKQAGLDTEQPPTTWEELTEMAPKLTDSSKNVSGFVFNKDGTAPLYNWMLA
                     NGGKLVNDDYTKSEFASPENLKTLKAIQKMIHVDKTGPESISGAEMDNLMNAGQLAIE
                     INGPWLNNGLKANEIDYNVTTLPQGSDSDKKTAILDGVGYAIPASTDNNKKEAVYEFL
                     KYWNTTEIGKKWSIENGFPAYLDSVAKDEEVKNDPIVSELSKQMDYAEPYLPGFTQIS
                     AINNDIINPLIEKLLAGEDPETLMNDADDAINQLLQK"
     gene            3090..3986
                     /locus_tag="ACG8LA_000599"
     CDS             3090..3986
                     /locus_tag="ACG8LA_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFQ0202927.1"
                     /translation="MNGFTKYWNRPDRAAYLFLTPSFLVLLLFTVIPLLGTFAISFTD
                     LNIFFTSRNFVSFENFTRIFSDERAVNSLIHSLYFTVLETPTQIIVGLLAAVALSKNT
                     RFNRFCRSTFYIPVICSLTSIAIIFSMLLDPNVGAIPYLFSQVGLPIPQFFRDPTLAM
                     PTVAIMTVWKNFGVTMTILLTAIQGISPSLYESAQMDGATNRQQFFNITLPQIVPSLG
                     FCILTNLIGSMQVFDQVYVATAGGPQFKTETAVQYIYSRGFTAPYELGYASALSSVLF
                     IIVATIAISTNVYMSRKEKQMK"
     gene            4000..4863
                     /locus_tag="ACG8LA_000600"
     CDS             4000..4863
                     /locus_tag="ACG8LA_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFQ0202928.1"
                     /translation="MAPESSITVTVNSRKAVSGKKIIRTISMLVILLVIAFPFLWLII
                     SSFKHEKDIISFPPRIFADSYTLDNYIKVWTTIPLLDYIKNTVIFAGGTVITSVFFDS
                     LAGYAFARMRFKGKSVLFYFVLLTMMIPFQVFMIPLFIEVNLLGMLDTYAGLIIPRMT
                     TAFGIFMMRSFFITLPDSLEEAARIDGLSEFNIFLKIMLPLSKPTLLSLGIFTLMNSW
                     NDLLYPLILTSSSKMRTLPAGLALFTGQNISFYGPVMAGTVISMLPLLVVYIFAQKYF
                     VQGTAMSGMKE"
     gene            4869..5432
                     /locus_tag="ACG8LA_000601"
     CDS             4869..5432
                     /locus_tag="ACG8LA_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HFQ0202929.1"
                     /translation="MKIVETKLYGQLIVVSDYILLGILWVIVCLPVITIVPATCAVFY
                     VMAQWKGEGSGNIIYFFFQGIKQHFGKNLFLSLLTIIIYFLVNQLLEEQTIVLSISGY
                     VVLLIYSMFLLSWIYVISENKDITFLQIFEQSAWKVFFDFLRNILCCVLLLGFVLLIF
                     LFPPFIFIFAGGVWKLVSIILTIGNER"
     gene            5454..6965
                     /locus_tag="ACG8LA_000602"
     CDS             5454..6965
                     /locus_tag="ACG8LA_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046556 - alpha-L-arabinofuranosidase
                     activity [Evidence IEA];
                     GO_process: GO:0046373 - L-arabinose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-arabinofuranosidase C-terminal
                     domain-containing protein"
                     /protein_id="HFQ0202930.1"
                     /translation="MKVKIREDFTVGEISSRLFGSFVEHMGSVVYTGIYEPGHETADG
                     DGFRQDVLSYVKELELGVIRYPGGNFTSGYDWVDTVGRKEQRPKKIDLAWRGIEPNSF
                     GLHEFFKWISHVQAKPIFTVNLGTKGIDEAKNLVEYCNFPKGTFWSDLRIKNGQKKPF
                     GVKLWCLGNELDGPWQVGAKSAYEYGRLANEASKVMKLVDDSIETILVGSSTPRLPSY
                     PEWDRIALEEAYENVDYLALHNYIDKYDEEDLTKPPKNERDDTATYLAKAYRFDRQIE
                     EIVATCDYVKGYLRSEKTMYLAFDEWNVHAQPEKRHRDFEVGSPIDWCYFTMEDTLLF
                     GSLGLAILRHADRVKISCQSLLVNTIPLILTDAKGQAWRNPTYYVMQHLSKYAKGQVL
                     KQQIICPVYDCEKIKNVPYVDSVIVDNGNQLTIFLINRTNEQQKITIEHDFNLLDQGE
                     HYTLTSSDLLDKNTREEPEKIKPEINYFSIEKHDELNVGIEKYSWNVIRIKKM"
     gene            6977..7936
                     /locus_tag="ACG8LA_000603"
     CDS             6977..7936
                     /locus_tag="ACG8LA_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="family 43 glycosylhydrolase"
                     /protein_id="HFQ0202931.1"
                     /translation="MMKTLYNNPIVRQRADPWVYKHTDGYYYFTGSVPGYQVIELRRA
                     KSLNELEHAASLIVWQAHEEGPMSELIWAPEVHYINGKWYIYFAASNHKTIRDESHHH
                     RMFVLENQHIDPMNTDWIEKGQIKTKRETFSLDGTTFSSQGKLYYVWAQQDPEITGNS
                     NLYLSEMDNPWTLKGKQILLSIPEYEWEKRGFSVNEGPAVLTRNGKIFITYSGSATDE
                     NYAMGLLWADEHKNLLLKESWHKLSEPVFVSSEKNKQFGPGHNSFTVSEDGCFDTLIY
                     HARPEKNQKGDPLDNPNRHANAQCFTWNEQGFPEFGEPVPYAL"
     gene            8022..9101
                     /locus_tag="ACG8LA_000604"
     CDS             8022..9101
                     /locus_tag="ACG8LA_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFQ0202932.1"
                     /translation="MAKYQDIAEEIKQKILREEYEVNTTIPSEFKLQEIYDVSRHTIR
                     QAIAVLVNEGYLRKEKGSGTYVDDSYKKEKTPLNRTKTIGVITTYLSDYIFPSIIRGI
                     ENELRESGYSLLLASTNNDHELEKECLKKMIAYGVDGLIVEPTKSNQYNPNLALYVAL
                     REQGIPMVMINAAYEELNASYICLDDVKVGFMAAEYLIKKGHQRLLFITKIDDLQGKY
                     RMKGFISACEQYNVRFLTEDIITFTTETRETIAEKTVQRLKEEQALDGIICYNDQIAS
                     LMLDKLTENGYHIPDDLSIVGTDDSSLSHLGNKKLTTLTHPKEKLGQDAARWIVTTIE
                     KGQAQPNILYEPVLVERETVKENEK"
     gene            complement(9353..10753)
                     /locus_tag="ACG8LA_000605"
     CDS             complement(9353..10753)
                     /locus_tag="ACG8LA_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0051119 - sugar transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar porter family MFS transporter"
                     /protein_id="HFQ0202933.1"
                     /translation="MKKEKKVSSSFIYFFGAFGGILFGYDIGVMTGALPFLQHDWGLA
                     GKASLIGWITSSVMLGAILGGSLSGLLSDKLGRRKMILLSALIFMAGSVLSASAPHNG
                     SYFLIAARILLGLAVGAASALVPAYMSEMAPARLRGRLSGINQVMIASGMLLSYVADY
                     LLKGLPETMAWRVMLGLAAVPALILFFGVLALPESPRFLMQSGRLEEAKRVLNYIRTP
                     KEAEQEFEQIQLNVKQEKTTGTSWHTLFLEKYRSLVIAGIGVAVFQQFQGANAIFYYI
                     PLIVEKATGHAASDALMWPIIQGIILVAGSLLFLVIADKFNRRTLLKIGGSVMGLSFI
                     LPAVLGTVLDAHTNSLLILLFLCIYVAFYSCTWAPLTWVIVGEIFPLAVRGRASGLAS
                     SFNWIGSFLVGLLFPVMTASMSQEIVFGIFGIICFLGVLFIQEIVPETRGKSLEEIEQ
                     SASKKTYPKRISIHHS"
     gene            10971..12632
                     /locus_tag="ACG8LA_000606"
     CDS             10971..12632
                     /locus_tag="ACG8LA_000606"
                     /EC_number="2.7.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004856 - D-xylulokinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0005998 - xylulose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="xylulokinase"
                     /protein_id="HFQ0202934.1"
                     /translation="MKEVNAQSMLDVIDGRTSLGIEFGSTRIKAVLIDSSFTPIAAGS
                     YEWENKLENGIWTYSLEDIWKGLRVSYRKMAAEVFEIYGENLTTIGSIGFSAMMHGYL
                     AFDSKEQLLVPFRTWRNTITEEAERILTEKFQYNIPQRWSIAHLYQSILNKEEHVKEI
                     NFLTTLAGYVHWQLTGEKVLGVGDASGMFPIDPSTKTYHQEMKNIFGQLIEKAHVAID
                     LDHILPKVLVAGEEAGKLSESGAYLIDPTGNLRPGIPVCPPEGDAGTGMVATNSVAKG
                     TGNISAGTSAFAMIVLEKELENVHPEIDMVTTPSGELVGMVHTNNCSSDINAWVSIFE
                     EFTNSLGMEISRDKLFTVLFNKALEGDTDCGGLLSYGYFSGENITGVNEGRPLFVRTP
                     GSRFDLANFMRIHLASAFGAMRIGMDILKSENVQIDRLVGHGGIFKTPEVGQRILASA
                     MEAPVTVMDTAGEGGAWGIALLAAYMMDRHGKSLENFLAEDVFGQDQGITITPSAEEI
                     AGYQIFMRRYREGIDIEKTAIHQLQEKGVIENAGTTERRSIPSKS"
     gene            12589..13287
                     /locus_tag="ACG8LA_000607"
     CDS             12589..13287
                     /locus_tag="ACG8LA_000607"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0008742 - L-ribulose-phosphate 4-epimerase
                     activity [Evidence IEA];
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0019569 - L-arabinose catabolic process to
                     xylulose 5-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HFQ0202935.1"
                     /translation="MLEQLKEEVYQANLDLPKHGLVKYTWGNVSAFDPETRYFVIKPS
                     GVSYEEMTADDMVVVDLDNHIIEGKLNPSSDTPTHAVLYRSFPQIGGIVHTHSTWATI
                     WAQAGLDVPAMGTTHADTFYGSVPCARFLTQQEIDSGYEYETGKVIIETFKERKIDPL
                     AIPGVLLHGHGPFTWGKDAQSAVMNAVVLDEVCKMNLFTRQLNSFSEELPQRILDKHY
                     LRKHGKNAYYGQNK"
     gene            13303..14727
                     /gene="araA"
                     /locus_tag="ACG8LA_000608"
     CDS             13303..14727
                     /gene="araA"
                     /locus_tag="ACG8LA_000608"
                     /EC_number="5.3.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008733 - L-arabinose isomerase activity
                     [Evidence IEA];
                     GO_process: GO:0005996 - monosaccharide metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose isomerase"
                     /protein_id="HFQ0202936.1"
                     /translation="MLNIGEKEFWFVVGSQHLYGEEALREVKKHAQEMVDELNENGQL
                     PYPIRLQELAVTADTITKIMKEVNYREEVAGVITWMHTFSPAKMWIRGTKLLQKPLLH
                     LATQYNESIPWKTIDMDFMNLNQSAHGDREYGFINARLNKQNKIVVGYWKRPEIQKEI
                     ADWMDVAVAYNESFGIKVARFGDNMRNVGVTEGDKVEAQIQFGWTVDYFGIGDLVQVI
                     DRVSDEEVDQLFEEYKELYTFDYGDYEEKTWEEHVKVQAQQEIGIRRFLEEGGYNAFT
                     TNFEDLYGMKQLPGLAVQRLMAEGYGFAGEGDWKTAAIDRLLKIMARGKDTGFMEDYT
                     YELASGQEAILESHMMEVDPTLAATKPRIVVSPLSMGDREDPARLVFDGKAGEGVVVS
                     MADFGTHYKLLINEVEAFEPTTEAPNLPVARVLWKTKPNFHEGVHSWIQAGGGHHTVV
                     SLNLTTDQIETWAKLVELETVVIR"
     gene            15034..16193
                     /locus_tag="ACG8LA_000609"
                     /pseudo
     CDS             15034..16193
                     /locus_tag="ACG8LA_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332175.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0051287 - NAD binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
     gene            complement(16170..16310)
                     /locus_tag="ACG8LA_000610"
     CDS             complement(16170..16310)
                     /locus_tag="ACG8LA_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoglycerate dehydrogenase"
                     /protein_id="HFQ0202937.1"
                     /translation="MLAPSFLSIKECCFSYFSCTKFESKERKEELMKSKYSLSLWPFW
                     FL"
     gene            16311..18170
                     /locus_tag="ACG8LA_000611"
     CDS             16311..18170
                     /locus_tag="ACG8LA_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HFQ0202938.1"
                     /translation="MKRYISRLSTKQKKILKGTAAIISIFFLVVFSNLFLQWCQNDLS
                     VDLALKFAFSWHTEKFFLACLVLLIILIFLIALAGSVPLGSLTYVVAIGVLGFANYMK
                     MSYRQEPIYPDDLKMITEIGLLKDMTGTMLFTVILAAAGTVIGLFCWYMFRSLKKGRR
                     FQLIRLTTLLVAIGLLGYISNFNNPDNLLRKAYNKTALWIPYSQKMNYYNTGFIGGFL
                     YNLKVEPMDEPEGYSKEKIKEITEKYQKLADEKNKTVEEESPNIVFVMSESFSDPSRL
                     NGVEVSGEPLADYYEVADQTYSGNMLSQNYGGGTANIEFEALTGFSMALFNAQLTTPY
                     TMLVPKMDQLPSIVSALNAQSYQTTAIHPYNTSMYKREDVYQTLGFDQFISERTMTYT
                     DTIENNPYISDESAYKEVMTLLKEEKTPQFIHLVTMQTHMPYDGKYDNLDYPAKTSDG
                     SGTLDLENYLQDISYSSTALKQFTEELKNLSRRTLVVFWGDHLPGIYSDTIQAKNDKQ
                     TLHETQFLMFDSKGELEKQTTHDAITSPFYFAANLMEQTNQTTNGFYQLLLSLEQELP
                     AFERELYYQNGQWYKEAQFNRSQQEIYDEYQLIQYDIVAGKQYSLADGFFEHE"
     gene            18280..18714
                     /locus_tag="ACG8LA_000612"
     CDS             18280..18714
                     /locus_tag="ACG8LA_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202939.1"
                     /translation="MLPNIGYYVQSIDQIVKETEAIGEGMHPKYEVIRNAIDEGKTSE
                     LDKSTLEEIILLFEEGTKKYRAMLMKVSTLRPPAKAMGIHKNFEKAYLSYVAGCEEMI
                     QSIDLESGVDEDLFNTSEAKQDQATDQLTAAIQKMTNLLLKK"
     gene            complement(18973..19134)
                     /locus_tag="ACG8LA_000613"
     CDS             complement(18973..19134)
                     /locus_tag="ACG8LA_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202940.1"
                     /translation="MNQQDVLDRLREELNIPFFDGKIEDKEYSEEEYQKLKADLQNYF
                     EQYVQNVEN"
     gene            complement(19153..20175)
                     /locus_tag="ACG8LA_000614"
     CDS             complement(19153..20175)
                     /locus_tag="ACG8LA_000614"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052689 - carboxylic ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HFQ0202941.1"
                     /translation="MIEKIILGTYTRRESKGIYTIDLDTEKEELANLSLAVEENSPTY
                     VAKSKAGNLYTVTSVDGLGGAGAYDKDFHFLNAVTESGAPLCYVAVDEARQLLYGANY
                     HKGEVNVYHILGDGELKAADSIFHQEATGPHKNQDHAHVHYTDLTPDQRLVVCDLGTD
                     RVYTYDVSENGKLNLVTTFTAEPGTGPRHLVFHPNGQFAYLFGELDSTVRVLSYNKET
                     GAFEELQKISTLPEEFDGENGGAAIRISNDGKFLYASNRGHNSIAVFAVFEDGSHIQN
                     KQIISTEGDFPRDFALDPSNNFVVCANQNTDNLTLYRRHPETGLLELLKKDVYVPECV
                     CVYFDR"
     gene            20303..20656
                     /locus_tag="ACG8LA_000615"
     CDS             20303..20656
                     /locus_tag="ACG8LA_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HFQ0202942.1"
                     /translation="MIQAKITEIGTEAINKEEPMLILFDKTATAALRKYSVIQEVSKD
                     EPFSLKAGGTIAFDDQVYTIDYVGPMANGNLKTVAHVSLIFDACPEEGQIANGIYLHP
                     HRLPAIGLGSQIFYN"
     gene            20668..21834
                     /locus_tag="ACG8LA_000616"
     CDS             20668..21834
                     /locus_tag="ACG8LA_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HFQ0202943.1"
                     /translation="MEGKNKKNRPVSWFWRWFLNNQVVTALLVVLLILLIVFLFTKVS
                     YLFAPIWQFLAIVGLPIILAGILYYLMNPVVDYFEKRKVPRLYSIIGLFVLVVALIAW
                     GSVVIIPKIQEQTVSFISNFPQYVDTIDNKLTEILRDPLFNQFREQLETAGDKFMNSA
                     GDMIQDISKSTVQSLGSFVGAVATILVALLTMPFILFYLLKDGKQLAPYFVKFLPTRM
                     QKPTLNVLSEMNSQVSSYIRGQLTVAFAVAIMFMIGFAVIGLEYAVTLGIIAGFLNLI
                     PYLGSFLAMIPAIFLAIVAGPFMIIKVLIVFAVEQTIEGRLISPLVLGNQLAIHPVTI
                     LLVLLTSGKLFGIIGVILGIPVYAAAKVVITHVFEWYTTISSLYEENPLKKQKE"
     gene            complement(21926..22546)
                     /locus_tag="ACG8LA_000617"
     CDS             complement(21926..22546)
                     /locus_tag="ACG8LA_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HFQ0202944.1"
                     /translation="MASVLVVKGHPLTAEESRTVKALTSFLTSYKENHPDDEVTVLEL
                     YRDDIPEIDEELLSGWEALRAGAEFTSLSESQQQKIARFNELTDQFLAADKIVIANAL
                     WNLNIPTKLKAWFDTVNVAGKTFRYTENGPEGLVTGKKALHIQSNGGVYNGQDFASQY
                     VKGILNFVGIDQVDQLFIEGIDYDPDRADELMQNALDKAAALGKSF"
     gene            complement(22738..23034)
                     /locus_tag="ACG8LA_000618"
     CDS             complement(22738..23034)
                     /locus_tag="ACG8LA_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HFQ0202945.1"
                     /translation="MAQSISVQDFNKLPLDADSIVLDTRNTLDYTKNHLSHSLSIPAA
                     ILPRQLKNLDPKKLYYILSYTGRRSEALADQLTANGFRAVYIIGGMEALQSSVA"
     gene            23238..23888
                     /locus_tag="ACG8LA_000619"
     CDS             23238..23888
                     /locus_tag="ACG8LA_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HFQ0202946.1"
                     /translation="MPTQTFFHLPKEKQKRLIEAARIEFSRVPLKEASIANIVKLADI
                     PRGSFYQYFEDKEDLYFYYFETMRRDSSKDMLQLMKESDGDLFKGFESYFSKMIYEIL
                     EGENASFYRNLFMNMDYRASRKVAPHTSRQKTPHDPHKEHKQDAKELLELIDRTKLKV
                     KNDHELELLIQLVMNTVFTTIAHSYRLFSTSEDYSVEQAISEFNLKLSWLKNGVYK"
     gene            23904..25631
                     /locus_tag="ACG8LA_000620"
     CDS             23904..25631
                     /locus_tag="ACG8LA_000620"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0202947.1"
                     /translation="MLKIVKRISLTSAIAAAVFMVIQVLADLYLPTLTSNIIDKGVAQ
                     GDVDYIWHTGFVMIGFSLISILAAIANTFFATRESQKLGKQLRTDVYKKSESLTKDAF
                     DKYGTASLITRTTNDVTQIQMVTQMFLRMMINAPITLIGASILAYQKDHQLTKIFLVV
                     IPVMIILIGGIMYFAVPLFKSMQKKTDRLNLVFREGLTGVRVIRAFDKTRFEENRFDL
                     ANKDYTNTAIKVNTIVALMMPMMTLIMSGTNVAITWFGGHYIADMTLEVGNLIAFMTY
                     AMQILISFMMLSAIFIMVPRAQASADRINEVLDEKIGIHDPENPKTVSFAGKNATLAF
                     NHVNYRYHGAEKLALEDIDFQAKSGEIVAIIGGTGSGKTTLVNLIPRLYDIESGSIQI
                     NGTDISDMTQYNLRELMGFVPQKAVLFSGTIRDNMQYGKPDATDEMIWKALEIAQAKD
                     FVSEMEDGLDSHVEQGGGNFSGGQRQRLAIARALVKTADIYVFDDSFSALDFKTDANL
                     RQALKTNMKESITVLVAQRVSTVMDADMILVLDEGKLVGKGTHEELLATNETYQEIVH
                     SQLREEDLA"
     gene            25628..27520
                     /locus_tag="ACG8LA_000621"
     CDS             25628..27520
                     /locus_tag="ACG8LA_000621"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0202948.1"
                     /translation="MSKTNTRPSHGPAGGPGHGGPGRNLGVKGEKPKNFWGTVRRLFG
                     YMSKRMVAIIAVFVLAIAAVIFQIQTPKVLGKATTEIFKGVMAGAQQMQQGQQVTKFP
                     IDFDKIAQIIATVIVMYLISAVFNFLQQFIMTRVSQRTVYELRHDLEAKMNRVPISYY
                     DTHTNGDIMSRAINDMDNIASTLQQNLTQFVTSAVTLIGVIVMMLSISWQLTLVALLM
                     IPLSLIIVMIVAPKSQVFFADQQKSLGLLNNQVEETYGGHTIVKTFNHTEKDQEVFEK
                     ENQNLYAAGWKAQFISAIIMPLMNFVKNLGYVFVAVLGGVKVANGNMTLGDVQAFLQY
                     TTQFSQPITQLASLMNTIQSTVASAERVFEVLDEEEMSNEKSGLPEEKDTPYKVRFEN
                     VQFGYTPDNLLMTDFNLDVKPGEMVAIVGPTGAGKTTLINLLERFYDVSGGSIRYDGV
                     DTRDLSRDELRAQFSMVLQDTWLFTGSIYDNIKYGNDDATDEQIIEAAKAAHVDDFVR
                     KLPEGYNTVLNEDASNISQGQRQLITIARAFLANPDVLILDEATSSVDTRTEILIQKA
                     MNRLLENRTSFVVAHRLSTIRDADNIIVMNHGSIVETGNHDTLMEKDGFYADLYNSQF
                     SEEEAS"
     gene            28224..29093
                     /locus_tag="ACG8LA_000622"
     CDS             28224..29093
                     /locus_tag="ACG8LA_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFQ0202949.1"
                     /translation="MKDFQLGAATYLKSVAIRVKDRDKMIDFYKNVVGFDLKREENEL
                     AILGTEEAGSEMLLLEESPRANDHMGVIKKLNRFSLIIPSTEEMADILCRIRKMNYPI
                     KEALEDHGRMGILLVDPEENELEIYHEENKNDQREIPETMDQEALLRKSEEKFSKLST
                     GSYFEKIHLNVTNLTKERQFLNHVLGLKVHNEEEGIHVLNEGDFHVGLTEASGGAIDL
                     PTDEVIGLDFLKFMIDTESMEGLIAHLQQLSVDFFLDKKHTVLTIYDAIGIEWWFVSE
                     PKEKNKTDIRCDA"
     gene            29302..30327
                     /locus_tag="ACG8LA_000623"
     CDS             29302..30327
                     /locus_tag="ACG8LA_000623"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase domain-containing protein"
                     /protein_id="HFQ0202950.1"
                     /translation="MYPHTKQLILKKMEEGFYPGVAVAFIKENQVETFTAGFAQVVPE
                     KQLMTEDLLFDAASLTKVVATTSLVLRLLEDGKIELDQPLHKYLPEFENQTITLRHLL
                     THTSDIKTWIPNRDKLSQEELIAAYLKLEPGEQLGKEVKYTDAGTILLGLMLEEIYQE
                     TAVEIFQEQVLEPLGMMNSLFLPFPSKKIVPTEQLPSGEVLRGQTHDPKARVLAEHAG
                     NAGLFIDLKDSITFVQMYLNKGKIRNGRFLEEETIDSLLQDQTPKKNGYRSLGWDLKK
                     DVEDGHAILFHTGYTGTFFLIDIKTQEALIFLSNRVHPVDHRAEYLICRDEIVENFLK
                     EKAVLPK"
     gene            30366..31316
                     /gene="manA"
                     /locus_tag="ACG8LA_000624"
     CDS             30366..31316
                     /gene="manA"
                     /locus_tag="ACG8LA_000624"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004476 - mannose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HFQ0202951.1"
                     /translation="MQEPMFLKPVFQEKIWGGSRLRSVFGFDIPNDKIGEDWAISAHP
                     HGVSVVENGEFKGKRLDELWSEHKELFGHPSEPVFPLLIKILDAEDDLSVQVHPDDAY
                     GMKHEGELGKTECWYIIDAEPGAEIIYGHHAKTREELAEMIKDGRWDDLLKKVPVKKG
                     DFFYVPSGTIHAIGKGIMILETQQSSDTTYRVYDYDRKDAQGQTRELHIQQSIDVTTV
                     PAKTPELQIKEVRKGNSSIVTYLETEFFNVYEWDIKGITSFKKQAPYTLMTVIEGAGD
                     LVVDGKTYPLEKGTSCIIPNGVSEWAVQGELAIIASEPGK"
     gene            31410..33113
                     /locus_tag="ACG8LA_000625"
     CDS             31410..33113
                     /locus_tag="ACG8LA_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFQ0202952.1"
                     /translation="MEYKWKANNSSRVSMKQLRKAGHHLNEMIMPNLSLFIAWGILSL
                     ATKGVSGDLHTTLEEVCHWMIQLLLPILISYSGGKSVGGQKGAVAGAIASLGLIARSN
                     APQIVGAMIIGPLAGIVYEQFVSRFHVKFKAGYEMLVSNLLVGLTGSVICIIGIVFIE
                     PVLNSVHLLLASVVSWLVTMNLLPLVSLILEPLKVLFFNNAINHGVLTPLGIEFSQTV
                     GYSSLFLMEANPGPGLGILLSILCFAEKQEKVNASGALMIHAIGGIHEIYFPFVLLRP
                     YLFLAVMAGGASGTLIFQWLDTGLAAPVSPGSLLVIFANAPYPQLAGVSIGIAISTFV
                     TFICAAILLKLPNKEKENKTVKERGEILEPSIIHSVIFACDSGMGSSAMGAALLKKKL
                     AAEKIDLSVGYSSIYELNNQVNQLVIVQHELAGLAREKVPQSQIYVLDHFLETDILLS
                     RIKEAIQFPKREEKKEIADITEQKTSPANIVFLYKNNRRGSQTMGMTILSQLAKKAKK
                     QFVISKESIEKIKIQEETIYIAQRELAVTEQLEEKIPRLVLVEHWVATNEYEKLVKGE
                     I"
     gene            33115..35148
                     /locus_tag="ACG8LA_000626"
     CDS             33115..35148
                     /locus_tag="ACG8LA_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HFQ0202953.1"
                     /translation="MYLSPREKQLLAEFLSSPSPVSIQKMMNLLKVSKRTIYRELDNL
                     EVSLKSVNASLKKAARGSFVIEASEEVLEQLKENTDGKSNDLSTAKRQHAILAELLLT
                     TEPLSLAHFMESYRISNTTFYADIKQLEESIRQLPLEIIRNQGYEIEGPEKYRRLLTA
                     NVLELEINEYELFHSISFDASLNYFFRFVDPQHLSLARKVIGEELIQKKTNLSDRKLE
                     HLVLMLTLTMERVTKNHLLTNETYNSLANKELLQTAKRLFSRIASETKQLYPVNEIVF
                     FAGLLNDFTNSFDQNFFEETFDTQLAYLVKQLIQEVSEETNVHFYEDETLYKMLLTHL
                     SGVFSRAVLQEETLTNPILEKIMVQYEEVANAIRKAVERIFQEKKLSEEEIAYMVLHF
                     ANSLERSPKESNISIAGFSPSGLASTSMLELRLKRYFPFIQQIHFYRIADLKKIDLQE
                     EYDVVISTSILPGYGGKYILVSPLLLEDEVKQLKEAFSHIEKKKRQKITYNSNNEWMI
                     EDTYEETMHFMDQINQLLGRFFIQELDNPETISETIRSLFPYFPEGLVTDEEVVHRRL
                     LKRYEQAPIGIPHTNMGLFHTSSSLISKPIFCIFNLKHPLTIEGMDRQPVDLSRMLVM
                     LAPSPIQEKDGILLGKISGAIIMNDLNTEIFRSGNKEIVYQLLAKILIEEIKK"
     gene            35159..35599
                     /locus_tag="ACG8LA_000627"
     CDS             35159..35599
                     /locus_tag="ACG8LA_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFQ0202954.1"
                     /translation="MIQLPAEKILLDQSYQNWKEALTEIGQWMTQQGGIKPAYIQSMI
                     ERQEKASVYIGNFVALPHGTDKDEEVVEEGIYLVQVPDGVDFGTKEEPKIATLLFVVA
                     LKKEHQLAVLQDLAFFCSDIDQVMALSDAETIEEVQMIFEHGHI"
     gene            complement(35799..36926)
                     /locus_tag="ACG8LA_000628"
     CDS             complement(35799..36926)
                     /locus_tag="ACG8LA_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFQ0202955.1"
                     /translation="MSLLTFERNLLLKNKVNFLFPLLLVVLFAFPLFFDHKLAYTEFD
                     ELNHNYEEMQRLIETLKEDENEKEFVESLEKSNKLIEAILHAKNTGNVQQMVEATYHY
                     EKDILDRLISGQRQGIPIIEQQKRVELLRYMKEHQIQRYSIFDLPAHLSLANYYENIF
                     SGMISSFLILCITALFLSSIISYEKRKQVISLVNLLPDSMVKKHSIRFTIYYGAAMLS
                     LVMPFLIVSILVIIKNGLGDFRYPVGTIIGQEIRILPMYEYLFQSFLFLLLWVLFLST
                     ISFLLSALFEHSLVNLLGTLLCLFLAEYRLFSSIGWIESISHYLPTSYVDFQNVIIGG
                     DIFSPLASEQVTFMNGILTLGIWSIVLLFIGMGTIYIKKSY"
     gene            complement(36929..37606)
                     /locus_tag="ACG8LA_000629"
     CDS             complement(36929..37606)
                     /locus_tag="ACG8LA_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HFQ0202956.1"
                     /translation="MTLLIKNMNMKRGKKRVIRQLNLLVESGEVAALIAPNGFGKTTL
                     LNGIAQLLPTTYDQLSLHNISPTAYTDYRRSFFFLESTNQLSDYLSAVDYLTLIKYYW
                     QSKVECQTVFQRLKMTEYLTLPIGKMSLGMKQHVLLAAYLISDSSVMLFDEPLNGLDP
                     GSIDILNSLIRQWQKEGKTILLSSHAIANIQSICSKACFLKNGEIVTESSNMEEILAI
                     YRKLYEV"
     gene            37870..39636
                     /locus_tag="ACG8LA_000630"
     CDS             37870..39636
                     /locus_tag="ACG8LA_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol-specific transporter subunit IIBC"
                     /protein_id="HFQ0202957.1"
                     /translation="MERTIPKNNISLKARVQKLGSTLSSMVMPNIGALIAWGVLTALF
                     IPDGYLPNEAFATMVSPMLTYLIPLLIGYTGGKVIAGDRGSVVGAIATMGVIVGTDIP
                     MMLGAMIMGPLGGYAIKKFDQLFQKRIKSGFEMLVNNFSAGLIGFGLALLGFSAIGPV
                     VDALTQAMAKGVEIILSAHLIPLTSIFIEPAKILFLNNAINHGILTPLGTEQVAEAGK
                     SILFLLEANPGPGLGVLLAFTLFGKGAAKSSAPGAMIIHFLGGIHEIYFPYVMMKPLL
                     FLSVIGGGMSGSFIFQLMDAGLRAPASPGSIIAILAMTPFNSYLPVILGVIVAAAVSF
                     GISAVILKADAKDTNEDFEKSVQETKAAKQASKGAQGIPQGATFSGVQKIIFACDAGM
                     GSSAMGASILRKKVQEADLPQTVTNQAISQLTDDSNTLIVTQVELQERAKQKAPSARF
                     VSVENFLNSPRYDEIIQELSSKQKTSVSEIENEPAEEFLSANIKQIKEILLVHDDRSG
                     SATMGMTVLKDILDKNHLTIPLRKVNIQDLKDEPDSLIVAKESLAEKVQMAAPQSIHL
                     SVNSMVNPQKYESIAQYLKQTA"
     gene            39651..40088
                     /locus_tag="ACG8LA_000631"
     CDS             39651..40088
                     /locus_tag="ACG8LA_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFQ0202958.1"
                     /translation="MQSLPFDMIELNRSFKTKEEAIRYCGQMLVEAGCVDEEYIDAMV
                     DRDKMLSVYMGNFIAIPHGTDEAKKYVKKSGICVVQVPDGVDFGTEEEEKIATVLFGI
                     AGVGDEHLQLVQQIALYCSDMDNVVQLADALSKEEVTENLAIA"
     gene            40101..41252
                     /locus_tag="ACG8LA_000632"
     CDS             40101..41252
                     /locus_tag="ACG8LA_000632"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HFQ0202959.1"
                     /translation="MRAVHFGAGNIGRGFIGEVLAANGFEITFVDVNHTIIDALNERK
                     EYEIELADESKEKITVKNVKGINNQTNPEKVIQEIAEADLVTTAIGPNILPFIAELIA
                     KGIQEREKEGSTTSLDIIACENMIGGSAFLEKEVYKYLPETSFTDKYIGFPNAAVDRI
                     VPLQHHEDPLFVQVEPFKEWVIDDSQRKNKKIQLKGVLYVDDLEPYIERKLFSVNTGH
                     ATVAYTGALLGYQTIDEAMQDALVVAQLKSVLQETGSLLIAKWGFDAEQHHAYIEKII
                     HRFQNKNISDAITRVARTPLRKLGYQERFTRPVRELQEHNLTCPHLTATMGIIFNYYD
                     PEDEQSRQLHEMKIHENLEQLIQEVTGINDPKTIGNIKQNVNRYAKQVA"
     gene            complement(41314..42012)
                     /locus_tag="ACG8LA_000633"
     CDS             complement(41314..42012)
                     /locus_tag="ACG8LA_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HFQ0202960.1"
                     /translation="MANYELNIAHLYGNLMNTYGDNGNLLMLKYIAEKMGVSCHTEIV
                     SIHEPFDADKYDLVFFGGGQDFEQLIISKDIQKKKDSLINYIENDGVMLAICGGYQLL
                     GHYYMGANGEKIQGISALDHYTLSQENNRFIGDIVIHNEEFNETYYGFENHNGRTFLG
                     EGERPLGKVVQGQGNNGEDQSEGVIYRNVFGSYFHGPILARNENLAARLIRLALEQRY
                     GKELDLPYLEGQTA"
     gene            complement(42005..43357)
                     /locus_tag="ACG8LA_000634"
     CDS             complement(42005..43357)
                     /locus_tag="ACG8LA_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurT ligase domain-containing protein"
                     /protein_id="HFQ0202961.1"
                     /translation="MGIRSHFAIAVGKTSQWALKTFFKGGSSLPGKLALKVDPHILDS
                     LAKDYQVVVVTGTNGKTLTTALTVNILRQQFDEVLTNPTGANMVQGIVSTFLQAKPKK
                     GQKKFAVLEIDEASLSKVTEYMKPELFLFTNIFRDQMDRYGEIYTTYKMIVDGAAKSP
                     NATIISNGDSPIFNSIETVNPRKYYGFDHEEDREQMAHYNTDGVLCPNCHHILHYKMI
                     TYANLGKYYCPNCDFKRPELDYRLTDMVRMDNVSADFVIDGHEYGIEVGGMYNVYNAL
                     AATAVAEYFNVDPDKIKQGLGYDEKVFGRQEVININGKKCTLVLVKNPVGINQVIDMI
                     GLAPYPFSLVALLNANYADGIDVSWIWDGNFENFADMDIPAVISGGDRHTDMTLRLKV
                     AGIPENKLTETKELPEVIEKIKELPTEHVYILATYTAVLQLRKELAAQGFIKGGMNRG
                     "
     gene            complement(43580..44980)
                     /locus_tag="ACG8LA_000635"
     CDS             complement(43580..44980)
                     /locus_tag="ACG8LA_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015079 - potassium ion transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HFQ0202962.1"
                     /translation="MHVDLFFRRLQRRGQKFAANHFSSIQIIVFYYILMTVLSLVLFY
                     MPIFREPDSHVSFVDMLFMAISTVSVTGLSTFDINSVFNDNGIILLEILFQVGGLGIM
                     MISTAFVIFSKRRITLKQRQLIMTDMNQPRLSGIVRLIRITFAILIWFQLLFGTFFSI
                     YFYYRGYFDRWRDAVFYGFYQAISAVTNSGFDVTGDSIKPFAHDYFFLILIMFLIFVG
                     GIGFPVLMECREWLLYKRSNAKLPFRFSLFTKLAVLAFVILFVSGTVLIYLLEKDHLF
                     QDSNMSVKWINSMFYSITTRNAGLQIHDLGDFQITTLIIFSLLMFIGCSPSSVGGGIR
                     TTTVAIIGLYLYSFLKSEDNINIFGRRIDQDDVRKSVVVFMLSLGMCFFCIVFLSATE
                     EQTLISIIIEVTSAFGTTGLSLGITGDLSVVGKITIATLMFIGRIGMLYTLMLFVPKE
                     TRDLGYEYPSEKIIIG"
     gene            45141..45878
                     /locus_tag="ACG8LA_000636"
     CDS             45141..45878
                     /locus_tag="ACG8LA_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
                     /protein_id="HFQ0202963.1"
                     /translation="MINAQQIVEKMKNQKINYDTVLKKMIMQWEKEEVKPKILIHTCC
                     APCSTHTLEFMSQYAEITLFFSNSNIHPKSEYLRRLHEQKRFVDQFNEKTDHHVALIV
                     DEYRPNEFTKMVLTNHLENEKEGGARCSACFNMRLDLVAQKAQELGYDYFGSALTISP
                     KKNAALINQIGMDIQKIYGTQYLPSDFKKNKGYERSLQMCKEYDIYRQCYCGCVFAAK
                     QQGCDLKEINREAKAYLKTSTVVFEEN"
     gene            46003..46482
                     /locus_tag="ACG8LA_000637"
     CDS             46003..46482
                     /locus_tag="ACG8LA_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A-agglutinin attachment subunit precursor"
                     /protein_id="HFQ0202964.1"
                     /translation="MRKVAPILKPIAVLTISTIVATTTGIVNSSSYRAPSSSSSTVEE
                     TTPTTSVSTSEPTTTESLNETTTTSTWDDTTTSSSYDETYTTDSSSETSNTVPDGTPS
                     DSTNPSTSPDTSASSETIPSSTTVDDNTQNDDAARTAQQNQDSGNTQTYNQQAGDSQ"
     gene            46479..47246
                     /locus_tag="ACG8LA_000638"
     CDS             46479..47246
                     /locus_tag="ACG8LA_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6681 family protein"
                     /protein_id="HFQ0202965.1"
                     /translation="MTFLLDLINGVHKFLGYLDISPKYLNRGYTILSVIPTLYLLRIV
                     YGLWQNQNYLQFFLYGLAFLVLVYFTVLNVFYYFLDKNTKADVTQLFVKYLPDEAFNI
                     QTEESIDNGNSIDKVNTQEVMVSYDEDYQLKLAENMRYLIGNGEIKTNELGRMDGFLV
                     DRNTLYPYYYVKKTGEKEYVLNIGRSYSDMEKVGTIRLDSTEDTLEPVGLFIVGGDFV
                     KDGLRYHEPYRLKLIAKKAQSQEEPVVYSRSQRRRHS"
     gene            47476..48045
                     /gene="lepB"
                     /locus_tag="ACG8LA_000639"
     CDS             47476..48045
                     /gene="lepB"
                     /locus_tag="ACG8LA_000639"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HFQ0202966.1"
                     /translation="MKEFLKNWGILILVLAAILLARVYVFTPVTVNGHSMDPTLSDGQ
                     RLISSKISNYERMDIITTKEPGDEERMIVKRIIGMPGDTVKMENDQLTINGKKYDEPY
                     LDEFKKEFSEDKLQGEYAYSSGFQAQAESSSTFTSDFEYTVPKGKYLVLGDNRLISKD
                     SRMFGLVDKDMIQGKVVFRYWPLSEIKIM"
     gene            complement(48149..48751)
                     /locus_tag="ACG8LA_000640"
     CDS             complement(48149..48751)
                     /locus_tag="ACG8LA_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HFQ0202967.1"
                     /translation="MTKNIFDSIANHYDSPDRQALAKIIREELTTYLPRDSHQKVLLD
                     YGGGTGLVSLPLAERFKELIIADASETMLKMAEEKIQAADLKNVRTIHADASVEFPAV
                     QANLILLSLVLLHIPDTENILTKLYEILAPGGQLIIVDFDKNEQISHPKVHNGFSQEE
                     LNNRLEKTGFVSATSHTFHRGEKLFMNKNASLFLSISQKA"
     gene            48857..49087
                     /locus_tag="ACG8LA_000641"
     CDS             48857..49087
                     /locus_tag="ACG8LA_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202968.1"
                     /translation="MPISFVKDREEKGKCVREILLDLPEWFGLPESTEKYIEESSKLP
                     LWCEKRKEEYLGFITLSQTSEDTAEIYSIVWE"
     gene            49078..49326
                     /locus_tag="ACG8LA_000642"
     CDS             49078..49326
                     /locus_tag="ACG8LA_000642"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: protein motif:HMM:NF025054.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFQ0202969.1"
                     /translation="MGIKKDYHHQGLGTKLFKEAEGYAAKHYKYLQVKTVDEGHYSIY
                     DQTICFYESLGFSRLEVFPNLWDEWNPCLVLVKKLEQK"
     gene            49432..50016
                     /locus_tag="ACG8LA_000643"
     CDS             49432..50016
                     /locus_tag="ACG8LA_000643"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004797 - thymidine kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HFQ0202970.1"
                     /translation="MAQLFFKYGAMNSGKTIEILKVAHNYEEQNKPVVLMTSGIDTRD
                     GLGVVSSRIGLKRNAMPIFEETDVFDVIQKMESKPYCVLIDEAQFLKKKHVIAFTRIV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLYADKIEEMKTICWFCHKKAIMNLHYIDGN
                     PVYEGDQVQIGGNEAYYPVCRKHYFHPSMITEGE"
     gene            50019..51092
                     /gene="prfA"
                     /locus_tag="ACG8LA_000644"
     CDS             50019..51092
                     /gene="prfA"
                     /locus_tag="ACG8LA_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003747 - translation release factor
                     activity [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HFQ0202971.1"
                     /translation="MYDQLQAIEDRYEELGELLSDPEVISDTKRFMQLSKEEANTRET
                     VEVYRRYKEVVQGITDTEELLGEKLDDEMAELAKEELSELKKEKEVLEEKIKILLLPK
                     DPNDDKNIIMEIRGAAGGDEAALFAGDLFNMYQKYAEAQGWKTEVMEANVTGIGGYKE
                     VIMMITGDNVYSKLKYESGAHRVQRVPSTESQGRIHTSTATVVVMPEAEEVEIDIEDK
                     DIRTDIYHASGAGGQHVNKTASAVRLTHLPTGIVVAMQDERSQIKNREKAMKILRARV
                     YDKIQQEAQSEYDANRKSAVGTGDRSERIRTYNFPQNRVTDHRIGLTIQKLDQILAGK
                     LDEIVDALIMYDQTSKLEAMQNG"
     gene            51085..51924
                     /gene="prmC"
                     /locus_tag="ACG8LA_000645"
     CDS             51085..51924
                     /gene="prmC"
                     /locus_tag="ACG8LA_000645"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0018364 - peptidyl-glutamine methylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HFQ0202972.1"
                     /translation="MGKMTYREVLSRASSFLEDHGKEAYSIQFLFLERKQWKKLDWLL
                     HMNEEISEEEQRLIETDLRLLLADHPPQYLLGYADFYDHRLKVTEATLIPRPETEELV
                     EWCLDETPGVPLEVIDIGTGTGAIAISLKAARKNWHISAVDLSEEALEVAKENAQKEG
                     TKISFYHGDTLGPVMDQQFDVIISNPPYISRNEWELMDESVRSFEPKMALFAENDGLA
                     IYEKIAVEAPSVLKSNGKIFLEIGFRQGEAVKKIFQQAFPDKKVAIKKDLFGNERMIQ
                     VYG"
     gene            51917..52096
                     /locus_tag="ACG8LA_000646"
     CDS             51917..52096
                     /locus_tag="ACG8LA_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202973.1"
                     /translation="MVEVVDEKFFICFFIIKKHLFDKDVNDFLVYQQVYPLLTNRLST
                     NSGKLEDKLRQNKNV"
     gene            52118..53143
                     /locus_tag="ACG8LA_000647"
     CDS             52118..53143
                     /locus_tag="ACG8LA_000647"
                     /EC_number="2.7.7.87"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003725 - double-stranded RNA binding
                     [Evidence IEA];
                     GO_function: GO:0061710 - L-threonylcarbamoyladenylate
                     synthase [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonylcarbamoyladenylate synthase"
                     /protein_id="HFQ0202974.1"
                     /translation="METKRYDETELQEAAEALKEGELVAFPTETVYGLGANALLPNAV
                     KKVFSVKGRPQDNPLIVHVASFEQVKEYVDNFHPAAEKIVKNFWPGPLTLIFKIKKDT
                     LPSVVTGGLSTAAFRIPDNKKTLEVIELSGVPLVGPSANTSGKPSPTTADHVYHDLQG
                     KITGIIDDGATRIGVESTVLDLSDPTAMPMILRPGAVTKEQIEAVIESPVAIDQHLVK
                     ENETPKAPGMKYKHYSPDTRVLMVRDGDWSTAVQWAKNKKIRAGVIASPEIADQVRTD
                     TAAVYMYNDNSVEAAAKGLFAGLRGLDEPTLGLDLIFVQVYPETGLGNAYMNRLKKAA
                     GQNYFEK"
     gene            53318..54562
                     /gene="glyA"
                     /locus_tag="ACG8LA_000648"
     CDS             53318..54562
                     /gene="glyA"
                     /locus_tag="ACG8LA_000648"
                     /EC_number="2.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004372 - glycine hydroxymethyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0070905 - serine binding [Evidence IEA];
                     GO_process: GO:0019264 - glycine biosynthetic process from
                     serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HFQ0202975.1"
                     /translation="MVDYKTFDPDLWAAIAKEEERQEHNLELIASENFVSEAVMAAQG
                     SILTNKYAEGYPGHRYYGGCEFVDIVENLAIDRAKELFGAKFANVQPHSGSQANTAAY
                     LALVEPGDTILGMDLSAGGHLTHGSPVNFSGKTYHFVAYGVDPTTEVIDYNVVRILAR
                     KHQPKLIVAGASAYGRTIDFAKFREIADEVGAKLMVDMAHIAGLVAAGLHPNPVPYAD
                     ITTTTTHKTLRGPRGGMILTNDEALAKKINSAVFPGIQGGPLEHVIAGKAVAFKEALD
                     PAFKEYSEQIIANAKAMVKVFNQAIGTRVISGATDNHLMLIDVRELGINGKEAESILD
                     SVNITVNKNSIPFETLSPFKTSGIRIGTPAITTRGFKEEDAVKVAELVVKALQAKDDN
                     AQLDEVKTGVRELTEKFPLHKK"
     gene            54715..55662
                     /locus_tag="ACG8LA_000649"
     CDS             54715..55662
                     /locus_tag="ACG8LA_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase fold domain-containing
                     protein"
                     /protein_id="HFQ0202976.1"
                     /translation="MTDRISLEKEAVAFSDANAPHPRIYELAPEEGRVLLEEVQESPV
                     NKYSVDIEDLMVDTGEWGKLNIRLVRPEGNMDKLPVIFYIHGAGWVFGSAQTHDKLIR
                     ELAVRTNSVVVFPEYSRSPEAKYPTAIEQNYAVLQQLNKLAKSKNLDLENLIVAGDSV
                     GGNMATVMTILTKERKGLPISKQLLYYPVTNADFDTDSYHEFGENYFLTREGMMWFWD
                     QYTTNEEERAEITASPLRANINELNDLPSAMILTGEADVLRDEGEAYARKLRDAGVPV
                     TQVRFQGIIHDFVMVNAMDQTKATRAAMALSTSWIKKKE"
     gene            55796..56425
                     /gene="upp"
                     /locus_tag="ACG8LA_000650"
     CDS             55796..56425
                     /gene="upp"
                     /locus_tag="ACG8LA_000650"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013774406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004845 - uracil phosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HFQ0202977.1"
                     /translation="MGKFQVIDHPLIQHKLTIIRDKNCGTKVFREVVDEIAMLMAYEV
                     SRDMPLEDIVIETPITETTQKTLSGKKVAIIPILRAGIGMVDGILELIPAAKVGHIGL
                     YRDEETLEPHEYFVKLPEDIDARQLFVVDPMLATGGSAIMAIDALKERGASNIKFVCL
                     VAAPEGVKALQEAHPDIDIYTASLDEKLNEHGYIVPGLGDAGDRLFGTK"
     gene            complement(56564..56806)
                     /locus_tag="ACG8LA_000651"
     CDS             complement(56564..56806)
                     /locus_tag="ACG8LA_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0202978.1"
                     /translation="MKMATFGKFDTTIVPSEIGEKFKINTHVMFTIHGKSQTGTISKQ
                     LKNSAVVEIDETAENANLMTQSKGVVIVNYKELKKI"
     gene            56927..56999
                     /locus_tag="ACG8LA_000652"
     tRNA            56927..56999
                     /locus_tag="ACG8LA_000652"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:56960..56962,aa:Thr,seq:cgt)
     gene            complement(57118..57756)
                     /locus_tag="ACG8LA_000653"
     CDS             complement(57118..57756)
                     /locus_tag="ACG8LA_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family glutamic-type intramembrane
                     protease"
                     /protein_id="HFQ0202979.1"
                     /translation="MNNILGKKIELKKGILGTIVVVLGLLGLLFAPSIISIFSLTITG
                     FIAFTLVFGKKDTKKMFSKPVAPVKNIAKYFFINVVISAAVSVFLQQILKWGLTGNPI
                     NEAFSPLLFIILPIMILGEELFSVYFLAIFSSKFSIPVASFLSAIIFGFIHYSTYDNG
                     NILHTVAHILLIQGVARLLFNQAAIKSNSIITSWAVHVIFDFTAILLVVLFS"
     gene            complement(57879..58511)
                     /locus_tag="ACG8LA_000654"
     CDS             complement(57879..58511)
                     /locus_tag="ACG8LA_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HFQ0202980.1"
                     /translation="MIFPKVNEASLNKGSFFHIYENEDFELYNILSQKEVIENQIICH
                     PIIYKSIFKYAFFASNDFQRMEITDCIFENCDFSGCILTKSMLHRVKFVNCKLTGTKL
                     MESYIGNTLFENCKMDYVNLSGSNIKESTFEHSVLSSADFVDCSLTKIMFSTNDLENA
                     SFFDTDLKNIDLSSNSFEMIEVRSEHLKNCTLNQLQALGFARKFLQIKVV"
BASE COUNT        19533 a        10251 c        12079 g        16864 t
ORIGIN      
        1 taaattattt gttttaatca ttattaatat tttggttaat taaaatcgat aaaaaataag
       61 taagtttaac atttatatta ttgacaacgc tttcaacgag gtgtattatt catgtataaa
      121 ttaaaggagg tcagttatgg aagccacaat gttgattagt agtgtcaagc gtgtaggcaa
      181 agttgatccg cggttgtaca gttcatttat tgaacatatg ggacgagcag tatatgaagg
      241 gatttatcag ccagatcatc catcagctaa taaaagtgga tttcgccaag acgtcattca
      301 cttggtaaaa gaattgaaca ttcccatgat tagatatcct ggtggaaatt ttgtgtcagg
      361 atttcgttgg gaagacagta ttgggcccat agcaaataga cctagaaggt tggatttagc
      421 ttggcggaca attgaaacga atgaagttgg gattcatgaa ttttataact ggtgtcagca
      481 tgtgggggcc gaaatcaata tggctgtcaa tctgggtact cgtggagtag atgcagctcg
      541 taatttagtc gaatattgta attttcctaa aggaacttat tggagtgatt taaggcgttc
      601 gaatggtcaa gagagccctt ttggaattaa gacatggtgt ttagggaatg aaatggacgg
      661 tccttggcag attggacata aaacagcgga agaatatgga cggttagcag aggaaacggc
      721 taaggcgatg aaactcgtag atgattcaat tgaggtggtt ttatgcggaa gttcgaatcg
      781 gcaaatgcct acatttggtg attgggagtt aacagttctt gatcaagcgt acgatcaaat
      841 agattatttg tctctgcatc aatattatgg caaccaaaaa aatgatcttt ctcattatct
      901 tgcacgttcc ttagacatgg atcggttcat ttctgaagtg acagcgatgt gcgatacagt
      961 caaggcgaag aaacatagta agaagcagat caacctgtcc tttgatgaat ggaatatttg
     1021 gtatcattca gcggaacaag atgagcaagc agcgccttgg cagattgctc ctcctttact
     1081 agaagataac tataattttg aagatgcatt actattaggc tgtctattaa tcactttatt
     1141 gaaacatgca gatagagtaa agattgcttg tcttgctcaa ttggtaaatg ttattgcacc
     1201 aatcaggaca gaaacaaacg gagaagcttg gagacagacg atctattatc catttatgca
     1261 agctgctgtg tatggacaag gagaggtgtt aagcccacaa attcgttcag caaactatgc
     1321 gacggaagat tttgaagaag tgccgtattt agaaagtata gccgtaataa atgacaaaga
     1381 acttgtcata tttgcagtta accgtggaga agaagaaatg aatctaactg ttcacttgtc
     1441 tgaattatca ttagagggag tgattgattt ttctgaaatg agtggatttg atacaaaagc
     1501 aactaatctt cctaaaagtg aacaagtaaa accaagtcat tcaacaaatg taaaagctga
     1561 agatgggaaa atcaattgtt tattgaaacc gctatcttgg aatgtggtca gatgtcgttt
     1621 atcagatgaa ggaggaacaa aaaatgaaag gtaaaaaatg gttaattggc tctttgttgg
     1681 tagctgcaac aggtatttta ggagcttgcg gtggcggaag ttcagcagaa tctgattctg
     1741 ataaagaagt gactttgact ttttggaatg ggtttactgc atctgatggt gaaatattgc
     1801 aagaaatcgt taatgaattt aataaaacaa atgataaaaa catcaaaatt gaaatggata
     1861 tcatgacttg ggccaatttg aatgaaaaac ttcctacagc gatttcttct aaaaaagcac
     1921 ctgactttat tgcattaaat tatccagatt ttgcacagta tgtagaaaac ggagcggtac
     1981 aaccattaga cgatttctgg gaatatgatg gagtagataa atctgatttt aaagaaacgg
     2041 ctattgaatt aggtgaagta gaaggtaaac agtattttgt ccccatgcag gtacaaggca
     2101 tgtatatgta ttggaataat gatttgttta aacaagctgg attagatact gaacaaccac
     2161 ctactacttg ggaagaattg acagaaatgg caccaaaatt aactgatagt agtaaaaatg
     2221 tatcaggttt tgtcttcaat aaggatggaa ctgcaccgtt atataactgg atgttagcaa
     2281 atggcggtaa attagtgaac gatgattata ctaagtctga atttgcgtct cctgagaacc
     2341 ttaaaacgtt aaaagcgatc caaaaaatga tccatgtaga caagactggt ccagaatcga
     2401 tttctggcgc cgaaatggac aatttaatga atgctggtca actagccatt gaaatcaatg
     2461 ggccatggtt aaataacgga ttgaaagcaa acgagattga ttataatgtg actaccttac
     2521 cacaagggag tgattcagac aaaaaaacag ctattttaga tggcgtagga tatgccattc
     2581 cggcaagtac agataataat aaaaaagaag ctgtctatga gtttttgaaa tattggaata
     2641 caactgaaat tggtaaaaaa tggagtatcg aaaatggttt tcctgcctac ttggattcag
     2701 tagcaaaaga tgaagaagta aaaaatgatc ctattgtatc tgaattatcg aaacaaatgg
     2761 actatgcaga gccatattta ccaggtttta cccaaatctc tgcgatcaat aacgatatca
     2821 tcaatccact gattgaaaaa ttattagcag gagaagatcc tgagacactc atgaacgatg
     2881 cagatgatgc catcaatcaa ttactgcaaa aatagtacag aactttatac aggatagact
     2941 gttggcaaga tacagatatc tgaatgatcg acctagtatt tgcagatagg tgttattgca
     3001 aaaatcacag cgattgttcg gatatcttat tcagattcgt ttaaaccaag attgtatatt
     3061 ttatcaaaat gaaagatgag gtggactata tgaacggatt caccaaatat tggaatcgtc
     3121 ctgatcgtgc tgcgtatttg tttttaactc catctttttt agttttatta ttatttactg
     3181 tcataccgct tttaggaaca tttgctatta gttttacaga tttgaatatt ttctttacat
     3241 caagaaattt tgtaagtttt gaaaatttca cacgtatatt tagtgatgaa cgagcagtta
     3301 attcgttgat tcattcttta tatttcaccg tactcgaaac gccaacacaa attatcgttg
     3361 gtttattagc agcagtagca ttatctaaaa ataccagatt caatcgtttt tgtcgttcga
     3421 cattttacat tccagttatt tgttcattga cgtcaattgc gattattttt tctatgttgc
     3481 ttgatccgaa tgtaggggcg attccttact tgttttcaca agtcggcttg ccgatccctc
     3541 aattttttcg cgatccaacc cttgctatgc cgacggtagc catcatgact gtttggaaga
     3601 attttggtgt tactatgacg attctcttga ctgctattca gggaatctct ccctctttgt
     3661 atgaatctgc tcaaatggat ggtgcaacaa atcgacagca gttttttaac attacgctac
     3721 ctcagatcgt tccctcctta ggtttttgta ttttaacgaa tctgattggt tcgatgcaag
     3781 tgtttgacca agtatatgtt gcaaccgctg gtggcccaca atttaagaca gaaacagctg
     3841 ttcaatatat ttacagtcga ggatttacag caccttatga attgggctat gcatcagcac
     3901 tgtcttcggt tttgtttatc attgttgcaa ctatagctat ctccactaat gtgtacatgt
     3961 cacggaaaga aaaacaaatg aaataggagg gaaacctgta tggcaccaga aagctcgatt
     4021 acagttactg tgaatagtcg aaaagcagtt agtggtaaaa aaatcattcg aacgattagt
     4081 atgctagtta tattgttggt tattgcgttt ccttttttgt ggctgattat ttcttctttt
     4141 aaacacgaaa aagacattat ctcatttccg cctagaatat ttgcagatag ctatacccta
     4201 gataactata ttaaggtttg gacaacgatc cctttattag attacatcaa aaatacagtg
     4261 atttttgctg gagggacagt gatcacttct gtattctttg attctcttgc ggggtatgca
     4321 tttgctcgta tgcgtttcaa aggaaaatca gttttgttct atttcgtttt gctgacaatg
     4381 atgatcccat tccaagtctt catgattcct ctatttattg aagtcaattt gcttggcatg
     4441 cttgatactt atgcaggttt gatcattcct cgtatgacaa ctgcatttgg tatcttcatg
     4501 atgcgttcct tttttattac tttaccagat tctttggaag aggcagcacg cattgatgga
     4561 ttaagtgagt ttaatatttt tttgaaaatc atgttgccat tgagcaaacc tactctttta
     4621 tcattaggga ttttcacgct gatgaatagt tggaatgact tgctttatcc attgatattg
     4681 acaagtagtt caaaaatgag aactttacca gcagggttag ctttatttac agggcagaac
     4741 atttcttttt atggacctgt aatggctgga acggttattt caatgctgcc attactagtg
     4801 gtttatattt ttgcacagaa atattttgtt caaggaacag ctatgtctgg aatgaaagag
     4861 tgaggaagat gaaaatagtt gagactaaac tttatggaca gttgattgtg gtttctgatt
     4921 acatcttatt aggtattctc tgggtaatcg tgtgtttgcc tgttattact atcgtgcctg
     4981 ctacatgtgc tgttttttat gtaatggcgc aatggaaagg tgagggatca ggaaatatca
     5041 tttatttttt ctttcaagga ataaagcaac attttggtaa gaacttgttc cttagtctgt
     5101 taacgatcat tatttatttt cttgttaatc aattattaga agaacagaca atcgtacttt
     5161 caattagtgg atatgtagtt ttacttattt attccatgtt tcttttatcc tggatatatg
     5221 tgatttctga aaacaaagat atcacatttt tacaaatttt tgaacaaagt gcatggaaag
     5281 tattttttga ttttttgaga aatattcttt gttgcgtatt gttattagga tttgtactgc
     5341 tcatatttct tttccctcct tttattttta tctttgctgg tggcgtatgg aaacttgtat
     5401 ctattatctt gactatagga aatgaaaggt agggaaagct gttggacgaa gaagtgaaag
     5461 taaaaatcag agaggatttt acggtaggag agatcagttc tcggctgttt ggctcatttg
     5521 ttgagcatat gggaagtgtc gtctatacag ggatttatga accgggccat gaaacagctg
     5581 atggtgacgg gtttagacaa gatgtcctct cttatgtaaa ggaattagaa ttaggtgtca
     5641 ttcgctatcc tggaggaaac tttacatctg gttatgattg ggtggatact gtaggtagga
     5701 aagaacaacg accaaaaaaa attgatttag catggcgagg tatagaacca aattcttttg
     5761 gactccacga attttttaaa tggatcagtc atgtacaagc gaaaccgata ttcacggtga
     5821 atttaggaac aaaaggaatt gatgaagcaa aaaatttagt agaatattgt aattttccaa
     5881 aaggaacctt ctggagtgat ttaagaataa aaaatgggca aaaaaagcct tttggcgtta
     5941 aattatggtg tttagggaat gagctagacg gtccatggca agtgggggct aagagtgctt
     6001 atgaatatgg taggttagca aatgaagcct caaaagtcat gaagttagtg gatgattcaa
     6061 ttgaaacaat cttagttgga agctctacgc cacgtttacc atcgtaccct gaatgggatc
     6121 gtatcgcatt agaagaagct tatgagaatg tagattattt agctttgcat aactatattg
     6181 ataagtatga tgaagaagac ttgactaaac ctcctaaaaa tgagcgtgat gatacagcga
     6241 cataccttgc aaaagcttat cgattcgatc gtcaaattga agaaatcgtt gctacttgtg
     6301 attatgtaaa aggatatttg agaagtgaga aaacaatgta tctagcgttt gatgaatgga
     6361 atgtacatgc ccaaccggaa aaaagacata gggattttga agtcggtagt cccatcgatt
     6421 ggtgttactt tactatggaa gatacattat tatttggttc attagggctg gctattttac
     6481 gacacgcaga tcgcgtaaag attagttgtc aatcattgtt agtaaacaca atacctttaa
     6541 tactgacaga tgctaaagga caagcatgga ggaatccaac ttattatgtg atgcaacact
     6601 tatcgaaata tgctaaaggt caagtattga aacaacaaat catttgccct gtttatgatt
     6661 gtgaaaagat aaaaaatgtt ccttatgtgg acagtgtgat cgtagataac ggcaatcagc
     6721 tgactatttt cttgatcaat cgcacaaatg aacaacaaaa gataacgatt gaacatgatt
     6781 tcaatttgct agatcaagga gagcactaca cattaaccag tagcgatctg ttggacaaaa
     6841 atacacgtga agaaccagaa aaaataaaac ctgaaataaa ctatttttca atagaaaaac
     6901 atgacgaatt aaatgtaggg atagaaaaat actcttggaa tgtaattaga ataaagaaaa
     6961 tgtgaggaaa tttgttatga tgaagacact ttataataat cctatcgttc ggcaacgggc
     7021 agatccttgg gtatataaac atacagatgg ttattattat tttacaggat cggttccagg
     7081 ctaccaagtg attgaattaa gaagggcaaa gtcactgaat gaattagaac atgctgcaag
     7141 cctgattgta tggcaggctc atgaagaagg accgatgagt gaattgatct gggcacctga
     7201 agtccattat atcaatggaa aatggtatat ttactttgct gcaagcaatc ataaaactat
     7261 acgtgatgaa tctcatcatc accgcatgtt cgtacttgaa aatcagcata tagatccaat
     7321 gaatacagat tggatagaaa agggacaaat aaaaacgaaa agggaaactt tcagtttaga
     7381 cggaacaact ttctcttctc aaggaaagct atattatgtg tgggcccaac aagatcctga
     7441 aattactggg aattctaatc tttatctatc cgaaatggat aatccttgga cgttaaaggg
     7501 gaagcagatc ctcctttcta tacctgagta tgaatgggaa aaacggggtt tttcagtaaa
     7561 tgaaggtcca gcagtcctta ctcgcaatgg gaaaatattc attacgtatt ctggtagtgc
     7621 aacagatgaa aactatgcca tgggcctgct gtgggctgat gagcacaaga atcttttatt
     7681 aaaagaatca tggcataaat tatcggagcc agtattcgtt tcttctgaaa aaaataagca
     7741 atttggtcct ggtcacaact cgtttacggt ttcagaagac gggtgctttg atactttgat
     7801 ctatcatgct cgaccagaga agaaccaaaa aggggatccg ttagacaatc ctaatcggca
     7861 cgcgaacgcg caatgcttta cgtggaatga gcaaggattt ccagaatttg gtgaacctgt
     7921 tccgtatgcc ttatgagcac aagaaacctt gatttttgct tgaataaacc ttgcagactc
     7981 gttatgatat atgtacgtac aaataaaaag gggcaaggca aatggcaaaa tatcaagata
     8041 ttgcagaaga gataaaacaa aagatccttc gtgaggaata cgaagtaaat acaaccattc
     8101 cctcagaatt caagctgcaa gaaatatatg acgtcagcag acatacgatt cggcaagcaa
     8161 tcgctgtgtt ggtaaatgag ggctatctgc gtaaagaaaa agggtcgggc acatatgtag
     8221 atgacagcta taagaaagaa aaaacaccat tgaacagaac aaaaacgatc ggtgtcatca
     8281 ccacatatct ctctgattat atttttccgt cgattatccg aggaatcgaa aatgaattac
     8341 gagaatctgg gtattcattg cttttagcca gtacgaataa cgatcacgaa ttggagaaag
     8401 agtgtttgaa gaaaatgatt gcttatgggg tagatggttt gatcgttgag cctacgaaaa
     8461 gtaatcagta taacccaaac ttagcacttt atgttgcttt gagagaacaa ggcattccga
     8521 tggtgatgat caatgctgct tatgaagagt taaatgcctc ttatatttgt ttagatgatg
     8581 tgaaagtcgg ttttatggca gcagaatatt tgataaaaaa aggacatcag cgtctgttgt
     8641 tcatcacaaa aatcgacgat cttcaaggaa aatacaggat gaaaggtttt atcagcgcgt
     8701 gtgaacagta taatgtgcgt tttttgacgg aagatatcat tactttcacc acggaaacac
     8761 gagaaacaat cgctgaaaaa acagtacaac ggttgaaaga agaacaagct ttagatggca
     8821 tcatttgcta taacgatcaa atagctagtt taatgctaga taagttgaca gaaaatggct
     8881 atcatattcc agatgaccta tcgatcgtag gaacagacga ttcttcttta agccatttag
     8941 ggaataaaaa attgacaaca ttgacgcatc caaaagaaaa gttgggacaa gatgccgcac
     9001 ggtggatcgt cacaacgatt gaaaaaggac aggcacagcc aaatattctc tatgaacctg
     9061 tactagttga acgggaaaca gtgaaagaaa acgaaaaata agagacgggt ttttaccgcc
     9121 tcttattgct cctacggtta ctcgtcgcaa tgtttgtgag agcttttgtc atcgctcaag
     9181 gctgaacgtt tctttcacca cctctccact aaacggtgtt ctcctaccaa ctggtcacaa
     9241 gtcacaatat tcatcaaaca tgagaagctg ttttttgaaa ttgttccttg tgactggaaa
     9301 ctaagcggtt ccttcttatt tcttgaagct gaccacttct gtcacaacct ctttaagaat
     9361 gatggataga aatacgttta ggataagttt ttttagatgc actttgttcg atttcctcta
     9421 aagatttccc acgagtttct ggtacgatct cttgaataaa taaaacccct aaaaagcaga
     9481 tgatcccaaa aatgccgaaa acgatttctt gagacataga agcagtcatc acaggaaaaa
     9541 gcaagccaac taggaaagaa ccaatccaat taaaagaaga ggctaggcca gatgctcgcc
     9601 cgcggacagc tagtgggaat atttcgccta cgattaccca tgtcagtgga gcccatgtgc
     9661 aagaataaaa tgcgacataa atacataaaa acaagagaat caacaacgaa tttgtatgag
     9721 catccagtac agttcctaaa acagctggta ggatgaaaga aagtcccatc acgctaccgc
     9781 ctattttcaa taaagttcgc cgattgaact tgtctgcaat aaccaaaaag agcaaagaac
     9841 cagcaactaa aatgattcct tggatgatcg gccacatcaa tgcatcgctc gctgcatgcc
     9901 cagtcgcttt ttctacgatc agcggaatat agtaaaaaat agcattagct ccttgaaatt
     9961 gctggaatac tgctacacca ataccggcaa tgactaagga acgatatttt tctaaaaaca
    10021 aagtatgcca agaagttccg gttgtctttt cttgtttgac attcagctgg atttgttcga
    10081 attcctgttc agcttctttt ggtgtccgaa tatagttcaa tactcttttt gcctcttcca
    10141 agcggccaga ttgcataaga aaacgcggtg actctggtag agctaaaaca ccgaaaaata
    10201 aaatcagcgc ggggacagca gcgagcccta acatcacgcg ccaagccatc gtttcaggca
    10261 acccttttag caaataatct gcaacatagg aaaggagcat gccagaagca atcatcactt
    10321 gattgatccc tgacaatctt ccccttagtc tagcaggagc catttcagac atataagcag
    10381 gaactagggc agatgcagcg ccaacagcta aacctagaag aatccttgct gcaatcagaa
    10441 aataagaacc attgtgaggg gcagatgcag aaaggacaga accagccata aaaataagtg
    10501 cagaaagaag aatcattttt cgtcgtccaa gcttatcaga aagaagacca gataaagagc
    10561 cgccaaggat cgcacctaac atgaccgaag acgtgatcca tcctatcaaa gaagctttac
    10621 ctgccaaacc ccaatcatgc tgtaaaaaag gtaaggcgcc ggtcataaca ccaatatcat
    10681 atccaaatag aatgccgcca aatgcgccaa aaaaataaat aaacgatgag gaaacttttt
    10741 tttctttttt cataagtatt ctctccttct agaatttcga gaaggcggtt gatcagattt
    10801 tgtaagcaat ttcattttat aacttatgta cgtacaaaac aagtgttttt tattgtattc
    10861 ttgtaaataa ctgcttgaca tgtacgtaca aaagtataca ataatcattg taagcgctac
    10921 taaaaagacg gtttgatcag gtttgacgag aaggagggag ttaaatcatt atgaaggaag
    10981 taaatgcgca aagtatgtta gatgtcatag atggtcgtac atctttaggg attgagtttg
    11041 gatcaactag gatcaaagct gtattgattg attcatcttt tactcctatt gccgctggta
    11101 gttatgagtg ggaaaacaaa ctagaaaatg gtatctggac ctattcatta gaagatattt
    11161 ggaaaggact gcgcgtcagt taccgaaaaa tggcagcaga agtattcgaa atctatggcg
    11221 agaatcttac gacaatcggg tcgattgggt tcagtgcaat gatgcacggt tatctagcat
    11281 ttgatagcaa ggaacagtta ctagtaccat ttcgtacttg gcgaaataca atcactgaag
    11341 aagcagaacg aatattaacg gaaaaatttc aatacaatat tccgcagaga tggagtatcg
    11401 ctcatttgta tcaatctatt ttgaataaag aagaacatgt gaaagaaatt aattttttga
    11461 caacgcttgc aggttatgtc cattggcagc ttactggtga gaaagtacta ggcgtaggag
    11521 atgcatcagg catgtttcct atcgatcctt caacgaaaac ctaccatcaa gaaatgaaaa
    11581 atatttttgg tcagttaatc gaaaaagcgc acgtagcgat tgacttggat cacattttgc
    11641 ctaaagttct agtagcagga gaagaagctg gcaagttaag cgaatcaggg gcttatctga
    11701 tcgaccctac gggaaatttg agaccaggaa tcccggtttg tccgccagaa ggggatgcag
    11761 gaaccggtat ggtcgctacg aacagtgtag ccaaagggac agggaacatt tcggctggta
    11821 cttccgcctt cgctatgatc gtattagaaa aagaactaga aaatgtccat ccggaaatcg
    11881 acatggtcac tacaccttca ggagaactag taggcatggt tcatacgaat aactgctctt
    11941 cggatatcaa tgcttgggtc agtatttttg aagaatttac caattctttg ggtatggaga
    12001 taagcagaga taaattattc acggtattat tcaacaaagc gctagaaggc gatacggatt
    12061 gcgggggatt actttcttat ggttattttt ccggtgaaaa cattacagga gtaaatgaag
    12121 gaaggccatt atttgtacgt acaccaggta gccgttttga tttagcgaat ttcatgcgga
    12181 tccatttagc cagtgctttt ggtgcaatga gaatcggaat ggatatattg aaatctgaga
    12241 atgtccaaat tgatcgttta gtggggcatg gggggatttt taaaacacca gaagttggac
    12301 agcggattct agcatctgct atggaggcac cagttacagt gatggacaca gccggagaag
    12361 gtggagcgtg gggaatcgcg ttattagcag cctatatgat ggatcgacat gggaagtctt
    12421 tagaaaactt cttggcagaa gacgtgtttg gacaagacca aggaatcacc atcacacctt
    12481 cagcagaaga aatagcaggc tatcagatat ttatgagacg ttaccgtgag gggatcgaca
    12541 ttgaaaaaac agcgattcat caattgcaag aaaaaggagt gatagaaaat gctggaacaa
    12601 ctgaaagaag aagtatacca agcaaatctt gacttgccta aacacggact cgtcaaatat
    12661 acatggggaa atgtgagcgc ttttgatcct gaaacacgat atttcgttat caaacctagc
    12721 ggagtcagtt atgaagagat gacagcagac gacatggtcg ttgtggactt ggacaatcat
    12781 atcattgaag gtaaactcaa tccctcttcg gatacgccta ctcatgctgt tttatatcgt
    12841 tcatttcctc aaatcggagg aatcgtccat actcactcga catgggcgac gatctgggca
    12901 caagcaggat tggatgttcc tgcgatgggg acgacgcatg cagatacttt ttatggatcg
    12961 gtaccttgtg ctcgattttt gacacaacag gaaatcgaca gcgggtacga atatgaaaca
    13021 ggaaaagtta tcatagaaac attcaaagaa cgcaaaattg atcccttagc aattccaggg
    13081 gtacttttac acggacacgg tccatttact tgggggaaag atgcgcaaag tgcggtaatg
    13141 aacgcagtcg tactagatga agtatgcaag atgaatttat ttaccagaca gctcaattca
    13201 ttttcagaag agctgcctca acggatttta gataaacatt atttacgaaa acacggaaaa
    13261 aatgcgtatt acggacaaaa caaataaaag gagtggctaa ttatgttgaa tattggagaa
    13321 aaagaatttt ggtttgttgt aggatcacag catttatatg gggaagaagc actgcgagaa
    13381 gtaaagaaac atgcacaaga aatggtcgat gaactgaatg aaaatggcca attgccttat
    13441 ccaatccgcc ttcaagaatt agcagttact gctgatacga tcacaaaaat catgaaagag
    13501 gtcaattatc gagaagaagt agcaggtgtg atcacttgga tgcatacttt ctcaccagca
    13561 aaaatgtgga tccgcgggac aaagcttcta caaaaaccat tgcttcattt agctacgcaa
    13621 tataacgaaa gcattccttg gaaaacgatc gatatggatt tcatgaattt aaatcaatcc
    13681 gctcatggtg accgcgaata tgggttcatc aatgctcgat taaataaaca aaataaaatc
    13741 gtcgttggct actggaaacg acctgagatc caaaaagaga ttgctgattg gatggatgtt
    13801 gcagtagcct ataatgaaag ttttggaata aaagtggctc gttttggtga caacatgaga
    13861 aacgtgggtg tcacagaagg agacaaagtg gaagcacaga ttcaatttgg ttggactgtt
    13921 gattattttg gtatcggaga tcttgtacaa gtaatcgatc gcgtatcaga cgaagaagtc
    13981 gatcaattat ttgaagagta caaggaattg tataccttcg actatggtga ttatgaagaa
    14041 aagacatggg aggaacatgt aaaagtacaa gctcagcagg aaatcggtat tcgccgtttc
    14101 ttagaagaag gaggctataa cgcttttacg actaattttg aagacctgta tggaatgaaa
    14161 caactacctg gactagctgt acaacgtttg atggcagaag gatacggttt tgctggggaa
    14221 ggcgactgga aaactgcagc gattgatcgg ttgctgaaaa tcatggctcg agggaaagat
    14281 acaggattca tggaagatta tacttacgag ctagctagtg gccaagaagc aatcttggaa
    14341 tcccatatga tggaagtaga tccgacgctt gctgcgacga aaccaagaat cgttgtttct
    14401 cctttatcaa tgggagatag agaagatccg gcgcgtcttg tatttgatgg gaaagcagga
    14461 gaaggggtag tcgtatcgat ggcagatttc ggtacgcatt ataaactgct gatcaatgaa
    14521 gtagaagcct ttgaaccaac gactgaagca cctaatttac ctgttgcacg tgtgttatgg
    14581 aaaactaaac cgaatttcca tgaaggtgtc cattcatgga ttcaggcagg tggcggtcat
    14641 cataccgttg tctcgctaaa tctaacaaca gatcaaattg aaacgtgggc aaaattagtt
    14701 gagttggaaa cagtggttat tagataaaaa gaggttgtga aaaagccact tagttttaag
    14761 aaataagaag agattgacga aatttgcttt tcaacttttt tgaaatttag tcttattatc
    14821 aatgtcagct aacggaacac catttatcaa gatatctcac cctcaatatt ttgctctcga
    14881 aaataaggct tatggcagta acttgtcata gccttatttt tatcactcag cctactctgc
    14941 tctaactgct ctttttgctt ctaggaagtc aaatggtaaa cagttgtcta attgcagaaa
    15001 tttcgagata cttgttagta aggagggggt tttatgtatc acgttcattt gattgatgct
    15061 attccagaac aagagataga aaagttacaa ggggaatatt tcaaaataat agatgatttg
    15121 ccagccgaag gaatagttat tcgtagtacg aaagtgaaag atgaatggct tacaccagat
    15181 ttgctagcaa tttcaagagc tggtgttggg gtgaacacga tcaacgttga aaaagcttct
    15241 gaaaacggga cgatcgtcat gaatacacca ggtgtaaatg ctaatgcagt aaaagagctt
    15301 gttttgtgct gtttgctctt atcttcccgt ccgataatcg aagcaagtcg tatggtacaa
    15361 acactaacag gtcctaatat tttagaacag gcagaaaaca aaagaagtgc ttatgtggga
    15421 cgagaattgc aaggcaaaac catcggtctt cttggtcttg gagcgatagg cacaaaagta
    15481 gcgctaagtt gctatagctt agggatggat gtcttgggtt attctatccg cgatgcccag
    15541 ttggattatg ttcggcaagc agatttagaa acagttcttt ctacctcgga ttacatcgta
    15601 gtcatgctgc cgttgacaga agatacaaaa ggattgatcg atcaggcgaa tatagaaaaa
    15661 atgaaaaaag atgctgtact tatcaatgta ggaagaagtg aaattgttga taaatatgct
    15721 gttatgcaag cattggaaaa acaacatctg gctaaatact tgactgattt tccagaagaa
    15781 gagttcttag aaaatgaccg tatacttatg ttgcctcatc taggggatcg actcaggaag
    15841 ctttggcaga cagcggacgt ttggcagttg aagccttaaa agattatctt ttgttcggta
    15901 cggttagaga agcggtcaat tatccatccg cacgaatgtt tttccaagcg ccgtttcgat
    15961 tcactatatt ttatcaaaag aaaaccaata tattagcaga gatattttct ctgctgaatg
    16021 agaacgagct agcgatcgca gatatatcgc gtaaccataa gaatgagcat gtctacatat
    16081 tgattgacat agacagtact gattttgaac agctcaatca agtgaaacaa cagctagaaa
    16141 aaatttctgg agtacgaaag gtccgcttat taaagaaacc agaaaggcca taaagaaaga
    16201 gaatatttgg atttcattaa ttcttctttc cgttctttac tttcgaattt cgtacaacta
    16261 aaataagaga agcaacattc ttttattgat agaaatgaag gagcaagcat ttgaaaagat
    16321 atataagcag actttcgacc aaacagaaaa agattttaaa aggaacagca gcaatcatca
    16381 gtatcttttt tcttgttgtt tttagtaatt tatttttgca gtggtgtcaa aatgatctat
    16441 ccgtagacct tgcgttgaaa tttgcttttt cttggcatac ggaaaaattc ttcttagcct
    16501 gtctcgtctt gctgattatt cttatttttc tgattgcact agcaggatct gtccctttag
    16561 gttcccttac gtatgtcgta gccatcggtg tattaggttt tgcaaattat atgaaaatga
    16621 gttatcggca agaaccgatt tatccagacg atttgaagat gatcactgaa atcggattgc
    16681 tgaaagatat gaccggcact atgctgttta cagtgatctt agctgccgca ggaaccgtga
    16741 taggattgtt ttgctggtac atgtttcgaa gcctgaaaaa aggaaggcga ttccaattga
    16801 tccgattaac gacactgctt gtggcaattg gactgctagg gtatatcagt aatttcaaca
    16861 atcccgataa tttgttgcga aaagcatata ataaaacggc actatggata ccttacagcc
    16921 agaaaatgaa ctactataac actggtttta tcggtgggtt tttgtacaat ctgaaggtag
    16981 aaccaatgga tgaacctgaa ggatattcga aagaaaagat caaagaaatc actgaaaaat
    17041 accagaagct agccgatgaa aaaaataaaa ctgtagagga agagtcgccg aacatcgtgt
    17101 tcgtgatgag tgaaagtttc tcagatccta gtcgattaaa cggcgtagaa gtatctggtg
    17161 agccattggc agattattat gaagtagctg atcaaacata tagtggcaat atgctttctc
    17221 aaaactatgg cggtggaaca gcaaatatcg aatttgaagc attgactggt ttttctatgg
    17281 cgttatttaa tgcgcaactc accacccctt acacgatgct tgtaccaaaa atggatcagc
    17341 ttccttctat cgtttcagcg ttaaacgcac aatcatacca gacgacagcg atccatccat
    17401 acaatacttc gatgtataaa agagaggatg tttatcagac attaggattt gaccagttca
    17461 tcagcgagcg tacgatgacc tatacggata cgatagagaa taatccatat atttctgatg
    17521 agtcagctta caaagaagta atgacacttc tcaaggaaga aaaaacacct cagttcattc
    17581 atttagtcac gatgcagaca catatgccct acgatggaaa gtatgataat ctagactatc
    17641 ctgcaaaaac ttcagatgga agtgggacac ttgacttaga gaattatctg caagatattt
    17701 cctatagcag cacggcactg aagcagttca cggaagaatt gaagaatctt tctagaagga
    17761 ctttagttgt tttttggggg gatcatcttc cagggatcta ttcagatacg atccaagcaa
    17821 aaaatgacaa acaaacattg catgaaacac aatttcttat gttcgacagt aaaggagaat
    17881 tagaaaagca aacgactcac gatgcaatca ccagtccgtt ttattttgca gcgaatctaa
    17941 tggaacagac gaatcagaca acaaatggct tttatcagct gcttttatca ttagaacagg
    18001 aacttccggc gtttgaacga gaactgtact atcaaaacgg acagtggtat aaagaagcgc
    18061 aattcaatcg ctcgcaacaa gagatttacg acgaatatca attgatccaa tatgacattg
    18121 tcgcagggaa acaatatagt ttagcagatg gtttctttga gcacgaataa gaatggcgag
    18181 ctgtatagaa accattaaat tttttcaagt acttgtcatt tgaggataaa aacaagtaga
    18241 ataaataata acaacaatgg agaaagtagg aaaacgaaca tgttaccgaa tattggctat
    18301 tatgtgcagt ccatcgatca aatcgtcaag gaaacagaag caatcggaga aggaatgcat
    18361 ccgaaatatg aagtgatcag aaacgcaatt gatgaaggaa aaacaagtga actggacaaa
    18421 tcgactcttg aagagatcat cctgttattt gaagaaggaa caaaaaaata tcgggcaatg
    18481 cttatgaaag tcagtacttt gcgtccacca gcaaaagcaa tgggcattca taaaaatttt
    18541 gaaaaagctt atctttcata tgtagcaggc tgtgaagaaa tgatccaaag tatcgatctt
    18601 gaatcagggg tagatgaaga tctattcaat acatctgaag caaaacaaga ccaagcgaca
    18661 gaccaattga cagctgccat ccaaaaaatg actaatttgt tgttgaaaaa ataaaagaaa
    18721 tctttgataa caataaaaac tagagttatc taatataaat gtaatattac ctttatgata
    18781 gagtgatcaa aatcctttat gataatgaca tacctataac caacaacaac cttgtactta
    18841 ctcaaaatcg agtaaatact ccttttccgt cgagtctaac catctcggcg gttttttatt
    18901 tgtagaaaag aacatcagga tagacggaaa agtcttgtcc tgatgttctt ttcagatagt
    18961 atggaaagct gattagtttt ctacattctg tacatattgt tcaaagtagt tctgtaaatc
    19021 ggctttgagt ttctgatatt cctcttcgct atactcttta tcttcgattt tcccatcaaa
    19081 gaaaggaata tttagttctt cccgtagtct gtctaatacg tcttgctgat tcatttcatt
    19141 ctccttttct tactaacgat caaaataaac acagacacat tctggtacat agacatcttt
    19201 tttcagtaat tccagtaatc ctgtttcagg atgacggcga tataatgtca gattatcggt
    19261 gttctgattg gcacacacga caaaattatt gcttggatct agtgcgaaat cgcggggaaa
    19321 atccccttct gttgagatga tttgcttgtt ttgaatgtgg gaaccatctt caaaaactgc
    19381 gaatacagca atcgagttat gtcctcggtt agaagcataa aggaacttgc catcatttga
    19441 aatgcggata gctgcccctc cattttcacc gtcgaattct tctggcaagg tcgatatttt
    19501 ctgtaattct tcaaaagcac ctgtttcttt attataagaa agcacgcgga ctgtgctgtc
    19561 taattcacca aataaataag cgaattgtcc atttggatga aagacaagat ggcgagggcc
    19621 tgttcctggc tctgcagtga aggtagttac aagattcaat ttgccgtttt cggacacatc
    19681 ataagtatac acacgatctg taccaagatc acatacgact aatcgttggt caggagtcag
    19741 atccgtatag tggacatgcg catgatcttg gtttttatga ggacctgtcg cttcttgatg
    19801 gaatattgaa tctgctgctt tcagttcgcc atctcctaat atatggtaga catttacttc
    19861 acctttatga tagttcgccc cgtatagtaa ttgacgtgct tcatcaaccg ctacataaca
    19921 caaaggagcg ccagactctg ttaccgcatt caaaaaatga aaatccttat cgtacgcacc
    19981 ggcaccacct aatccatcca cactagtaac tgtgtaaaga ttgccagctt tactttttgc
    20041 tacataggta gggctatttt cttcaacagc taatgaaagg ttggctaatt cttctttttc
    20101 tgtatcaagg tcgatcgtat agattccttt actttcgcga cgcgtatagg ttcctaaaat
    20161 tatcttttcg atcatatgag ctgattcctc ctaattgtaa tgaaatagtt ttcgttttta
    20221 ttctatcaca taattattcc acacggctaa agaatgagaa tgtgttatac tgtttttgaa
    20281 agcaattaaa ggagagagtg caatgattca ggcaaagatt acagaaattg ggacagaagc
    20341 aataaacaag gaagaaccca tgctgatttt gttcgataaa acagcaacag ctgccttacg
    20401 aaaatattcg gtgattcaag aagtatcaaa agacgaacct ttttctttga aagcaggcgg
    20461 aacaattgct tttgatgatc aggtatatac gatcgattat gtcggtccga tggccaatgg
    20521 gaatttaaag acagtagctc acgtatcatt gatttttgat gcttgtccag aagaaggaca
    20581 aattgcaaat ggaatctatc ttcatccgca tagactgcct gctattggtt tgggaagcca
    20641 aattttttat aactaacagg aggaattatg gaaggaaaaa ataagaagaa cagaccggta
    20701 tcgtggtttt ggcgctggtt tttaaataat caagtagtca cagccttact tgttgtattg
    20761 ttaatattgc tgatcgtctt tttatttaca aaagtttcat atttgtttgc accaatctgg
    20821 caatttttag caatcgtagg tctgcctatc attttagcag gaatcttgta ttacttgatg
    20881 aatccggtag ttgattactt tgaaaagcga aaagtaccaa ggctttacag tatcattggg
    20941 ctgtttgttt tggttgttgc actaatcgca tgggggagcg tagtgatcat ccctaagatt
    21001 caggaacaaa cagtgagctt catcagtaac ttccctcaat atgtagatac gattgataat
    21061 aaattaaccg agattttgcg ggacccgctg ttcaaccaat ttcgcgaaca gttggaaaca
    21121 gcaggtgata agttcatgaa ttcggcaggc gatatgatcc aagatatatc taagagtaca
    21181 gttcagagtc ttggaagttt tgtcggcgcg gtagcgacta ttttagtggc tctgctgacg
    21241 atgccgttta tcttatttta tctattgaaa gacggtaaac aattagcacc ttattttgtc
    21301 aaatttttac cgacacgcat gcaaaaaccg acgttgaatg tgctgagtga aatgaatagt
    21361 caagtttctt cttatataag aggacaacta actgtggctt ttgctgtggc aatcatgttt
    21421 atgattggtt ttgcggtcat tggtttagag tatgctgtca cgttggggat tattgcgggt
    21481 tttttaaacc tgatccctta cttaggatca tttttagcga tgattccggc tatcttttta
    21541 gccattgtag caggtccatt catgatcatc aaagtactga tcgtttttgc agtagagcag
    21601 acaatagaag gacgcttgat ctctccatta gtactaggga atcagttagc aatccatcca
    21661 gtaacgattt tattagttct gctgacttct gggaaattgt tcggaatcat cggtgtgatc
    21721 ttggggattc ctgtttatgc agcagctaaa gtagtgatta ctcatgtttt tgaatggtac
    21781 acaacaatct cttctcttta tgaagaaaat ccgttgaaaa agcagaaaga ataacaaaaa
    21841 gagacagatg ggaaaatatc caaggcacaa atgctgcttt gaagattttt tcctctgtct
    21901 cttttgtatg catttatctc aatttttaaa atgatttacc taaagcagca gctttatcta
    21961 atgcattttg catcaactca tctgcacggt cagggtcata atcgattcct tcgatgaata
    22021 gctgatctac ttgatcgatg cctacaaagt ttaaaatacc ttttacatat tgagaggcaa
    22081 agtcttgtcc gttgtataca ccgccattag attggatgtg cagtgctttt ttacctgtca
    22141 ctaatccttc tggcccgttt tctgtatagc ggaacgtttt tccagctaca ttgacggtat
    22201 cgaaccaagc ttttaatttt gttgggatat ttagattcca taaggcgttt gcgataacga
    22261 ttttatcagc agcaaggaac tgatcagtca attcattgaa acgagcaatt ttttgttgtt
    22321 gactttctga taaggaagtg aattctgcac cagcacgtaa tgcttcccaa cctgataata
    22381 attcttcatc gatttccgga atatcatcgc gataaagttc caaaacagtc acttcatcat
    22441 ctggatgatt ttctttataa cttgttaaaa aagacgtcaa tgccttaact gtgcgcgatt
    22501 cttctgcagt taggggatga cctttgacta ctaaaacaga tgccatatgc ttaccttctc
    22561 cttttattgc tatgattgtt ataactatga ctaacaaaat cagtttactc gaaaaagaaa
    22621 aggctatcaa gtcatattga taaggttgaa gaataaataa ctaaaaaaag acagggtata
    22681 aaagaggctg tgacacgatt ttttgtcaca gcctcttttg aatctaacaa gcaatattca
    22741 agcaacactc gactgaagag cttccatccc accaatgata taaacagcac gaaaaccatt
    22801 agcagtaagt tgatcggcta atgcttctga tcgcctgcct gtatagctta gaatataata
    22861 aagtttcttt ggatctagat tttttaattg tcttggcaag atagcagcgg ggatagaaag
    22921 cgagtggctt aagtggtttt ttgtgtaatc taaggtattt cttgtatcta aaacgatgct
    22981 gtcagcatcg agaggcaatt tattgaagtc ttggacacta attgattggg ccatttatct
    23041 catcctttgt ttagtatgtg gctattttaa tgggcaactc tcattaattc aaatggaagg
    23101 attcctctta tcactttttt aatgtatcgg atgataatga aaaaaactat gcaaatgtct
    23161 tgcaaaacag gtaggaggtg ttataatgac atagcgtcat atgacaatgt gtcatcttga
    23221 aagaaaggag aatccatatg ccgacacaga catttttcca tttgcctaaa gaaaaacaaa
    23281 aaagactaat cgaggctgcg agaatcgagt tttctagagt acccttaaaa gaagcttcga
    23341 ttgctaatat cgtcaaatta gcggatatcc ctagaggcag tttctatcag tattttgaag
    23401 ataaagagga tctttatttt tattactttg agacaatgag acgtgacagc tctaaagata
    23461 tgttacaact aatgaaagaa tccgatggtg atctattcaa aggattcgaa tcctattttt
    23521 ctaaaatgat ttatgagatt ttggaaggcg agaatgcttc tttttatcgt aacttgttta
    23581 tgaacatgga ttaccgtgcc tcaagaaaag tcgctcctca tacgagtcgc caaaaaacgc
    23641 ctcacgatcc acataaagaa cacaaacaag atgcaaaaga gttgcttgaa ttgatcgatc
    23701 ggacgaagct gaaagtaaaa aatgatcatg aattggaatt actgatccaa ttagtgatga
    23761 atactgtatt tacaacaatt gcgcattcgt atcgcttatt ttcaacatct gaagattact
    23821 cagtagagca agcaatcagt gaattcaatt tgaaactttc ttggctgaaa aacggagtat
    23881 ataaatagaa agaagggaac tagatgctaa aaatcgtaaa acggatctcc ttgacttcag
    23941 caattgcagc tgcagttttc atggtgatcc aagtactggc agatttatat ttgccgacac
    24001 ttacctccaa tattattgat aaaggggtag cgcaaggaga tgtcgattat atttggcata
    24061 caggttttgt gatgatcggc ttttctttga tcagtatctt agctgctatc gcaaatacat
    24121 tttttgctac tcgtgaatca cagaaactgg gtaagcaatt gcgtacggat gtctataaaa
    24181 aatcagagag tctgacaaaa gatgcgtttg ataaatatgg aacggcctct ttgatcacaa
    24241 gaacgaccaa tgatgtgact caaatccaaa tggttacaca aatgttttta cgtatgatga
    24301 tcaatgcacc aatcacgttg attggcgcga gcatacttgc ttatcaaaaa gatcatcagt
    24361 tgacaaaaat cttcttagtt gtcatcccag taatgattat tttgatcggc ggaatcatgt
    24421 actttgctgt tccattattc aaaagtatgc aaaagaaaac tgaccgttta aacctggtat
    24481 ttcgagaagg attgacaggg gtcagagtga ttcgagcatt cgataagaca cgctttgaag
    24541 aaaatcgttt tgatttagcg aataaagatt atacaaatac ggcaatcaaa gttaatacga
    24601 tcgtcgcatt gatgatgcca atgatgacat tgatcatgag cggtacaaac gtagcaatca
    24661 cttggtttgg tggacactac atagcagata tgactttgga agtcggtaat ctgattgcat
    24721 ttatgactta tgcgatgcag atcttgatca gctttatgat gctttccgct atttttatca
    24781 tggtgcctcg tgcacaagct tcagctgacc gtattaatga agtgttggat gaaaaaatcg
    24841 gtatccatga ccctgaaaat cctaaaacag tttcttttgc tggaaaaaac gcaacattgg
    24901 ccttcaatca tgtcaattat cgatatcatg gagcagaaaa acttgcattg gaagatattg
    24961 atttccaagc caagtcgggc gagatcgtcg caatcatagg ggggactggt tcaggtaaaa
    25021 cgaccttagt caatttgatc cctcgattat atgacatcga atctggttcg atccaaataa
    25081 atggaacgga cattagtgac atgactcaat ataatttgcg agaattaatg ggctttgttc
    25141 ctcaaaaagc agttctgttc tctggaacga tccgagacaa tatgcagtat ggtaagccgg
    25201 atgcaacaga tgaaatgatt tggaaagcat tagaaatcgc acaagctaaa gattttgttt
    25261 cagagatgga agatggctta gatagccatg tggaacaagg aggaggaaac ttctctggtg
    25321 gacaaagaca gcgtctggca attgcacggg cattagtcaa aacagcagat atctatgtgt
    25381 ttgatgattc cttctcagcg ttggatttca aaacggatgc caatcttcgc caagcattga
    25441 aaacgaatat gaaagaaagt atcaccgttt tagttgctca acgagtaagt acagtaatgg
    25501 atgcagatat gatccttgtg ctagatgaag gaaaactggt tggcaaagga acacatgaag
    25561 aactattagc aacaaacgaa acttatcaag aaatcgttca ttcacaacta agagaggagg
    25621 acttagcatg agtaaaacaa acacacgtcc ctctcatgga ccagcaggcg gtccaggaca
    25681 tggtggacct ggcagaaatc tcggtgtaaa aggtgaaaag cctaaaaatt tctggggaac
    25741 ggtacgccga ttgtttggct atatgtctaa acgtatggtt gcgatcatcg ctgtatttgt
    25801 actagcaata gcagccgtga tcttccaaat ccaaacacca aaggtcttgg ggaaagcaac
    25861 cacagaaata ttcaaaggtg taatggctgg cgctcaacag atgcaacaag gccaacaagt
    25921 aacaaaattt ccgatagact ttgataaaat cgcgcagatc attgcgacag taatcgtgat
    25981 gtatttgatt tctgctgtat tcaacttttt acagcaattt attatgacac gtgtttccca
    26041 acgaacagtt tatgaattac gtcatgattt ggaagccaaa atgaatcgtg taccgatttc
    26101 ctattatgat acacatacaa atggggatat catgtctcga gcaatcaatg atatggataa
    26161 catcgcaagc acgctgcagc aaaatttgac tcaatttgta actagtgcag tcacattgat
    26221 tggggtcatc gtgatgatgc tttcaatcag ctggcaattg acgttagtcg cgttattgat
    26281 gatcccttta agcttgatca tcgtgatgat cgtagcgccg aaatcacaag tgtttttcgc
    26341 agatcagcaa aaaagtttag gtttattgaa taaccaagta gaagaaacat atggtggtca
    26401 taccattgtt aaaacattca atcatactga aaaagaccag gaagtatttg aaaaagaaaa
    26461 tcagaatctg tatgccgctg gttggaaagc tcaatttatt tcggcaatca tcatgccgtt
    26521 gatgaatttc gttaaaaatc taggctatgt gttcgtcgct gtactaggcg gagtaaaagt
    26581 tgcaaatggg aacatgacat taggggatgt tcaagcgttc ttgcaatata caacacagtt
    26641 ctctcaacca atcactcaac ttgcaagttt gatgaacact atccaatcaa cagttgcttc
    26701 agccgaacgg gtatttgaag tgttggatga agaagagatg tccaatgaaa aatctggcct
    26761 tccagaagaa aaagatacac catacaaagt tcgttttgaa aatgttcaat tcggctacac
    26821 accagataac ttgctaatga ctgattttaa cttggatgtc aaacctggtg agatggtcgc
    26881 tattgtaggt ccgactggtg cagggaagac gacactgatc aaccttcttg aacggttcta
    26941 cgatgtttct ggaggtagta ttcgttacga tggtgtagat acccgtgatc tttcacgtga
    27001 tgaattgcgc gcacagtttt caatggtact gcaagatact tggctgttta caggaagtat
    27061 ctatgacaat atcaaatatg ggaacgacga tgcaacagac gaacaaatca ttgaggctgc
    27121 taaagctgct cacgtagacg attttgttcg taaattgcca gaaggatata acactgtatt
    27181 aaacgaggat gcaagcaata tttcgcaagg gcagcgtcag ctaatcacaa ttgcgcgggc
    27241 attcttagca aatccagatg tcctgatcct tgatgaagca acatctagtg tagatacacg
    27301 aacagaaata ctgattcaaa aagcgatgaa ccgcctattg gaaaaccgga caagtttcgt
    27361 tgttgctcac cgcttgtcta caatacgcga tgcagacaac attattgtga tgaatcatgg
    27421 ttcgatcgta gaaacaggaa accacgatac attgatggaa aaagacggat tctatgcaga
    27481 tctttataac agtcagtttt ctgaagaaga agcttcatag aatagtacaa atttattatt
    27541 ttttttaggg gctgtgacaa aagtcgtgtc acagtccctt tttccgaata aacggtgttc
    27601 aatcagctgt ccttcggtat tagctcaaaa aacggcaaaa tatgagaagc tatttttccg
    27661 ttttgtatct ctaatactca ggtcaaaccg ctgattttac aacctcttcc ttaaacggtg
    27721 ttctcctgcc aactcctcgg tcacaagtca caatagtcaa caaacctgag aagctgtttt
    27781 ttgaaattgc tccttgtgac tcggagttaa acggcaggct cacaacctct tggtaaacgg
    27841 tgttcaaaag ccagtttctc ggtattaagc caaatttatg caaaaatgta gaaagccatt
    27901 ttcacaaaat ttttcttact actcgaaact aagcgacttt ttcacaacct cttccttaaa
    27961 cggtgttcaa aagcttgcat ctgcggtaat aagcccaacc aaacgaaaaa taggaggagc
    28021 tatttttgtt tggctgttct tattacttga tgcagaacag ctttttcaca acctcttttt
    28081 ataagagttt ttactcatta atttacaaaa aacaagcaaa atgcgaattt tctcacattt
    28141 tttttaacaa aatcaaagtt attgcttgaa agaagaagaa tccatcgtta aaataaagct
    28201 tgacgtagag gggagcaaga aatatgaaag attttcaatt gggggctgcc acctatttaa
    28261 aaagtgtagc cattcgggtg aaagaccgag ataaaatgat tgatttttac aagaacgttg
    28321 ttggctttga tttgaaaaga gaagaaaacg aattagccat tttaggaaca gaagaagctg
    28381 gaagtgaaat gttgctgctg gaagaaagtc ctagagcgaa tgatcacatg ggggtgatca
    28441 aaaagctgaa ccgtttttca ttgattatcc ctagcacaga agaaatggca gatatccttt
    28501 gtcgtatccg taaaatgaat tatccaatca aagaagcttt agaagatcat ggacgtatgg
    28561 ggattttgct cgtagaccca gaagagaatg aattggaaat ttaccatgaa gagaataaga
    28621 acgaccaaag agaaattcca gaaacaatgg atcaagaagc attattaaga aaatctgaag
    28681 aaaaattcag taaactatca acaggttctt attttgaaaa aatccattta aatgttacta
    28741 acttaacaaa agaacgccaa tttcttaatc atgtacttgg tttgaaggta cataatgaag
    28801 aagagggcat ccatgtattg aatgaaggag atttccatgt tggtttgaca gaagctagcg
    28861 gaggcgcaat tgatttgcct acagatgaag tgattggact tgattttctg aaattcatga
    28921 tcgatactga aagcatggaa ggactgattg ctcacttgca gcaactatca gttgatttct
    28981 tcttagacaa aaagcacaca gtactcacaa tctatgatgc tataggaatc gaatggtggt
    29041 tcgtcagtga gccaaaagaa aagaataaaa ctgacattcg atgcgacgct taactttttc
    29101 tttcttaacg attgtcgcat gtctcgtcat tttatgaacg gtcatactat cgcttattct
    29161 agagatagaa agagaaaata gtataccggg ggaaactgcg cggtttttcg cgcagttttt
    29221 ttgtgtaaaa aaggttgatt cctcatagat taagctttaa gcttggactg taagaatctg
    29281 atagaaaagc aggagaaaaa gatgtatcca cacacgaaac agcttatttt gaaaaagatg
    29341 gaagaaggat tttatccagg tgtagcagtc gccttcataa aagaaaatca agtagaaaca
    29401 tttacagccg gctttgccca agtcgttcct gaaaagcagc tgatgacaga agatctgttg
    29461 tttgatgcag cctcactgac gaaagtcgtt gcaaccactt cattagtttt acgtctatta
    29521 gaagatggaa agatagaact cgatcaaccg cttcataaat atcttcctga atttgaaaat
    29581 cagacaatca ctttgcgtca tttactgaca catacttctg atatcaaaac atggatacca
    29641 aacagagata agctatctca ggaagaattg atcgccgctt atttgaagct agaaccaggt
    29701 gagcaactag gaaaagaagt aaaatataca gatgccggta cgattcttct tgggttgatg
    29761 ctagaggaaa tttaccaaga aactgcagtg gaaatctttc aagaacaagt attggaacca
    29821 ttaggaatga tgaacagctt atttcttcct tttccttcca aaaaaatcgt tcccacagaa
    29881 caactgcctt cgggtgaggt tttgcgtgga caaactcatg atccgaaagc aagagttttg
    29941 gctgaacatg caggtaacgc gggtctcttt attgatttga aagacagcat tacttttgtc
    30001 caaatgtatt tgaacaaggg aaaaatccgt aatggtcgtt ttttagaaga agagacgatt
    30061 gattctttac tgcaagatca aacaccgaaa aaaaatggct atcgttcttt aggatgggac
    30121 ttaaaaaagg atgtagaaga cggtcatgcg attctttttc atactggtta tacaggtacg
    30181 tttttcttga ttgatataaa aacacaagaa gcgttgatat ttttgtcaaa tcgcgtacat
    30241 cctgtcgatc atcgtgcgga gtatctcata tgtcgagatg aaattgttga aaactttttg
    30301 aaagagaaag cggtattacc gaaataatgc tataatagct atgaaaaatg agaggagttt
    30361 gaattatgca ggaacctatg tttttaaaac cagtttttca agaaaaaatt tggggaggaa
    30421 gtcgtttacg ttcagtcttt ggttttgata tccctaacga taaaatcgga gaagattggg
    30481 cgatcagtgc gcatcctcat ggtgtcagtg tagtagaaaa tggcgaattc aaagggaaaa
    30541 gattagatga actatggtca gaacacaagg aattgtttgg ccatccttca gaaccagtgt
    30601 ttccattatt gatcaagatc ttagacgcag aagatgatct atctgtacaa gtacatccag
    30661 atgatgccta tgggatgaaa catgaaggtg aattaggaaa aactgaatgc tggtatatca
    30721 tcgatgctga acctggtgca gaaatcatct atggtcatca tgcaaagaca agagaagaac
    30781 tagctgagat gatcaaagat gggcgctggg atgacctttt gaagaaagta ccagttaaaa
    30841 aaggtgattt cttttatgta ccaagcggaa cgatccatgc tattggtaaa ggaatcatga
    30901 ttttagaaac acagcaaagt tctgacacga cttaccgcgt gtatgactac gacagaaaag
    30961 atgcgcaagg acaaacaaga gagctgcata tccaacaatc gatcgatgta acaactgtcc
    31021 ctgcgaaaac accagaatta caaatcaaag aagtccgaaa agggaattca tcgatcgtca
    31081 cttatttaga aactgagttt ttcaatgtat atgagtggga tattaaagga atcacatctt
    31141 tcaaaaaaca agccccttat acattgatga cggtaatcga aggagcagga gaccttgtcg
    31201 ttgacggaaa aacatatcca ttagaaaaag gaacaagctg tattattcca aatggcgttt
    31261 ctgagtgggc ggtccaaggt gaactagcaa tcattgcgtc tgaaccaggc aaatagttcc
    31321 cagatagctg aaagcagcag acggtttttc gtttgctgct ttttctacat aaaatccgtc
    31381 catcaataaa tagaagtctg gtgaaaaaga tggaatacaa atggaaagca aacaacagca
    31441 gtcgcgtgtc tatgaaacaa ctgagaaaag ctggacatca cttaaatgaa atgatcatgc
    31501 caaatctaag tctgtttatc gcttggggaa tcttgtcatt agcaacaaaa ggtgtgtctg
    31561 gcgatttgca caccacatta gaagaggtat gccattggat gatccagctg cttttaccca
    31621 tcttgatcag ttattcaggc gggaaatcgg tagggggaca aaaaggggca gtcgccggtg
    31681 caattgcttc tttagggttg atcgctcgtt ccaatgctcc acaaatcgta ggagcgatga
    31741 ttatcgggcc gcttgccggc atcgtatatg aacaatttgt ttctagattc catgtgaaat
    31801 tcaaggctgg atatgaaatg cttgtcagca acctactagt aggactgact ggtagcgtta
    31861 tttgtataat tggaatcgtt tttattgaac cagttttaaa tagtgttcac ttgttgctcg
    31921 cctccgttgt gtcttggcta gtcacaatga atctgttacc acttgtcagt ctgatcttag
    31981 aacctctaaa agtactattt ttcaataatg caatcaatca tggtgtattg acacctttag
    32041 gaatcgaatt ctcacaaaca gtcgggtact cttccttatt tttgatggag gcaaatcctg
    32101 gacctggttt agggatctta ctttctatcc tttgttttgc agaaaaacag gaaaaagtaa
    32161 atgcgagtgg agcattgatg atccatgcga ttggcgggat tcacgaaatc tattttccat
    32221 ttgtcttgct gcgaccgtat ctatttttag ctgtaatggc tggtggggca agcggcacgt
    32281 tgatatttca atggttagat acgggattag ctgcacctgt atcgcctggg tcactactcg
    32341 tgatttttgc caatgcgcct tatccacaac tagctggggt aagtataggg atagcaatca
    32401 gtacatttgt gaccttcatt tgtgcagcga tactattgaa attaccaaat aaagaaaaag
    32461 agaacaaaac ggtcaaagaa aggggagaaa tcttggaacc atctatcatt cattccgtca
    32521 tttttgcttg cgactcaggt atgggatcaa gtgctatggg agccgccctg ctgaaaaaga
    32581 aattagcagc agaaaaaatc gatctttctg tcggatacag ctctatctat gaattgaata
    32641 accaagtaaa tcagctggtt atcgtgcaac atgaactagc gggtcttgca agagaaaaag
    32701 tacctcaaag tcaaatctat gtactggatc actttttgga aacagatatc ttgctgtcac
    32761 gaataaaaga agcgatccaa tttccaaagc gggaagaaaa aaaagagata gcagatatca
    32821 cagaacaaaa aacgtcgcct gctaatattg tatttttgta taaaaacaac agacgcggct
    32881 cacaaactat gggcatgacg attttaagtc aattagcaaa aaaagcgaaa aaacagtttg
    32941 ttatctcaaa agaatcaata gaaaaaatca aaatccaaga agaaacgatt tatatcgcac
    33001 aaagagaact agctgtaact gaacagctag aagaaaagat ccctcggcta gttctagttg
    33061 aacattgggt agctacgaat gaatacgaaa aactcgtgaa gggagaaata taagatgtat
    33121 ttatcgccca gagaaaaaca attattagca gaatttctca gtagcccgtc acctgtatct
    33181 atccaaaaaa tgatgaattt attgaaggtc agtaaacgga ctatttaccg cgaattagat
    33241 aatcttgaag tctcattgaa atcggtaaat gcttctttga aaaaagcagc tagaggctca
    33301 tttgtcattg aggcatcaga agaagtatta gagcaattaa aagaaaatac agatgggaaa
    33361 agtaatgact tatccactgc taaacgacaa cacgcgattt tagccgagtt gttactgacg
    33421 acagagccgt tgagtcttgc tcatttcatg gaatcatatc gcatcagtaa taccactttt
    33481 tatgcagata tcaaacagtt ggaagaaagt attcgccaac tgcctttgga aatcattcgg
    33541 aaccagggat acgagatcga aggaccggaa aaataccgcc ggcttctgac agcgaatgta
    33601 ttagaattag aaatcaatga atatgaactt tttcatagta tttctttcga tgcatcactg
    33661 aattattttt ttcgattcgt tgatccgcaa catctatctc ttgcacgcaa agtaatcggg
    33721 gaagaattga tccaaaaaaa gaccaatcta agtgatagaa agcttgaaca tttggttttg
    33781 atgctgacat tgacgatgga gcgtgtgacg aaaaatcatt tactgacaaa tgagacatat
    33841 aatagtctgg caaacaaaga attactacag acagctaaac gattgttttc acggatcgct
    33901 tctgagacaa aacaacttta tccagtaaat gagatcgtct tttttgcagg attattaaat
    33961 gacttcacga actcatttga tcagaatttc tttgaagaga cgttcgatac acagcttgct
    34021 tatttagtaa aacaactgat tcaagaagta agtgaagaga cgaatgtcca tttttatgaa
    34081 gatgaaactt tgtacaaaat gctgttgact catttatctg gtgtgttttc aagagccgtt
    34141 ttacaagaag agacactgac caatccgatt ttagaaaaaa tcatggttca atacgaggaa
    34201 gttgcgaatg caatccgtaa agcagtagag cggatttttc aagaaaaaaa attatccgaa
    34261 gaagagatcg cttatatggt ccttcatttt gcgaattcat tggaacgaag tccgaaagaa
    34321 agcaatatca gtattgcagg attttcgcca agtggattag cttctactag catgttggaa
    34381 ctacgattga aaaggtattt tcccttcatc caacaaattc atttctatcg gattgctgat
    34441 ttaaaaaaaa tcgatttaca agaagaatat gatgttgtta tttctacatc tattttacca
    34501 ggatacggtg gaaaatatat tttagtctcc ccgctactgc tagaagatga agtcaagcag
    34561 ctaaaagaag ctttttcgca tattgagaag aaaaaaaggc aaaaaattac gtataacagc
    34621 aataacgagt ggatgataga agatacttat gaggaaacaa tgcatttcat ggatcaaatc
    34681 aatcaattac tcggtcgttt ttttatccaa gaactggata atcctgagac gatttccgaa
    34741 acgattcgca gcttatttcc ttattttcct gaaggactag taacggatga agaggtggtt
    34801 catcgccggc tgcttaagcg atatgaacaa gcacctatcg gtattcctca tacaaatatg
    34861 gggttattcc atacatccag ctcattgatt tctaaaccga tcttttgtat tttcaatttg
    34921 aaacatccgt tgaccattga agggatggat agacagccag tcgatttgtc ccgtatgtta
    34981 gttatgctgg cgccttcgcc aatccaagaa aaagacggga ttcttttagg aaagatcagt
    35041 ggagcaatca tcatgaatga cttgaacacc gagatcttcc gctcaggaaa taaagaaatc
    35101 gtttatcagt tgttagcgaa aatcctgatt gaagaaataa agaaatgaag gtgaaaagat
    35161 gatacagcta ccagcagaaa aaatattgct cgatcaatcc tatcaaaatt ggaaagaagc
    35221 gttgaccgag atcggccagt ggatgaccca acaaggggga atcaaaccgg catatatcca
    35281 atcaatgatc gaaagacaag aaaaagcgag tgtctatatc gggaatttcg tagccttgcc
    35341 acatgggact gacaaagatg aagaagtagt agaagaagga atctatttag tccaagtgcc
    35401 tgatggtgtg gactttggaa caaaagagga accaaaaatc gcgacactct tatttgtagt
    35461 ggctttaaaa aaagaacatc agttagcggt gctccaagat ttagcctttt tctgttcaga
    35521 catcgaccaa gtaatggcgc tcagtgatgc ggaaaccatt gaagaagtcc aaatgatttt
    35581 tgaacatgga catatataac caatgttcac agtaaaaaaa gctgccttgc atcaagtaat
    35641 aacttcaacc aagataaaaa taagaggagc tatttttgtt gggaggttct tattactgcg
    35701 gatgcaagct tttgaaaact atttattcta gaaaaccgtt tatttgaaat aggggacggt
    35761 gacaaggttt ttgtcaccgc ccctattatt tttgtgtttt aatagctctt ttttatatag
    35821 atagtgccca tacctatgaa taataaaacg atactccata taccaagtgt caagatacca
    35881 ttcatgaaag taacctgttc tgaagctagt ggcgagaaaa tatctcctcc tatgatcaca
    35941 ttttgaaaat caacataaga agttggcaag taatgactga ttgattctat ccatccaatc
    36001 gaagaaaaca agcgatactc tgctaagaaa agacaaagaa gtgtacctaa aagattgact
    36061 agagaatgtt caaataaagc agatagaaga aaactgattg tacttaaaaa gagcacccac
    36121 aacaacagga acagaaagct ctggaaaaga tactcataca tcggcaggat tcgtatctcc
    36181 tgaccaatga tcgttcctac aggataacgg aagtctccca aaccattttt gattattact
    36241 agtatagaga cgatcaaaaa tggcatcacg agacttagca tagctgcacc ataataaatg
    36301 gtaaaacgga tgctatgttt ctttaccata ctatccggta atagattgac tagagagatt
    36361 acctgctttc ttttttcata agagatgatg gaagaaagaa acaaggcggt tatacataaa
    36421 atcaaaaaac tagaaatcat tcctgaaaaa atattttcgt agtaatttgc taaagagaga
    36481 tgcgctggca agtcaaaaat agaatatctt tggatctgat gttctttcat ataacggagc
    36541 aactcgacac gtttttgttg ttcaatgatt ggaattcctt gtctttgacc agaaatcagt
    36601 cgatccagta tatctttttc ataatgataa gttgcttcga ccatttgctg gacattccct
    36661 gtgttttttg catgtaagat tgcttcgatc agtttgttgc ttttctctaa actttccaca
    36721 aattctttct cattctcatc ttctttcaac gtttcaatca aacgttgcat ctcttcatag
    36781 ttatgattca gttcatcgaa ttctgtataa gcaagtttat gatcaaaaaa aagtgggaat
    36841 gcaaagagca cgaccaacaa tagaggaaat aaaaagttta ctttgttttt tagtaagaga
    36901 ttgcgttcaa atgtaagtaa agacatagtt acacctcata taatttacga taaatagcta
    36961 aaatctcttc catatttgag gattctgtga cgatttctcc attttttaga aaacatgctt
    37021 tagaacaaat cgattggata ttcgcgatag cgtgggaaga aagaagaatc gtcttcccct
    37081 ctttctgcca ttgtctgatg aggctattca agatatcaat acttcctggg tctaatccgt
    37141 tcaacggttc atcgaataac atgacagatg aatcactgat caagtaagca gcaagcaaga
    37201 catgttgttt cattcctaga gacatttttc caatcggcaa agtaaggtac tcagtcatct
    37261 tcaatcgttg gaaaacagtt tggcattcta ctttgctctg ccaatagtat ttgatcaaag
    37321 tcaaataatc aacagccgat agatagtcgg ataactgatt cgttgattct agaaaaaaga
    37381 aagaccggcg ataatctgta taagcagtag gagagatgtt gtgaagggac aattgatcat
    37441 aagttgttgg cagcagttgg gcaatgccat tcagcaaagt tgttttgcca aatccgttcg
    37501 gggcaatcaa agcagctact tctcctgatt ctactaaaag attcaattgt cgaatcacac
    37561 gttttttacc acgtttcatg ttcatgtttt tgatcagtaa tgtcatagat aggcctccaa
    37621 tataaaattt aataacataa tagaatggaa aacatctaaa ttaaatgcta acaaaagtta
    37681 ttgtttgcat attataaaaa aattaaaata acagttttat ttaaaattga agttttctga
    37741 taccgaaatc tttttatttt gctgacatac tcaaaccttt ggcacaaagt ttcgtgccaa
    37801 agtacgacta tttctctttt tagtaagcgg atacaattag agtatcaaaa ggagagaggg
    37861 agagacaaaa tggaacggac gattcccaaa aacaacattt cgctaaaagc gagggtacaa
    37921 aaattaggca gtactttatc aagcatggtc atgccaaata ttggagcact gattgcctgg
    37981 ggtgtattaa cggctctatt tatcccagat ggttatttac caaatgaggc tttcgctacc
    38041 atggtaagcc caatgctaac ttatctgatt cctttattga tcggttatac tggcggaaaa
    38101 gtaattgctg gtgaccgcgg atcagttgtt ggggcaattg caacgatggg tgtgattgtc
    38161 ggaacagata ttccaatgat gctaggcgcg atgatcatgg gacctcttgg tggatatgcc
    38221 atcaagaaat ttgatcagct attccaaaaa cggatcaaat ccggttttga aatgctagtc
    38281 aataattttt cagcaggtct tatcggtttt ggattagcgt tattaggttt ttctgcgatt
    38341 ggtccagttg tcgatgcatt gactcaagca atggcaaaag gtgtagagat cattttatct
    38401 gcccatttga ttccattgac aagtattttt attgaaccag caaaaatctt atttttgaat
    38461 aatgcaatca atcatgggat tttgacacca ttgggaactg aacaagtagc agaggctgga
    38521 aaatctattc tattcttgct tgaagcaaat cctggtccag gacttggcgt attacttgct
    38581 tttactttgt ttggcaaagg agcagcaaaa tcttcagcac caggagccat gatcattcac
    38641 tttttaggcg ggatccatga aatctatttt ccttacgtta tgatgaaacc gttattattc
    38701 ttatcagtta taggcggagg aatgtcagga agtttcattt tccaattgat ggatgctgga
    38761 ctaagagcgc cagcttctcc agggtcgatc attgcgattc tagcgatgac accgttcaat
    38821 tcttaccttc ctgttatttt gggcgtgatt gttgccgcag ctgtttcgtt tggtatttct
    38881 gcagtaattt tgaaagcgga tgcgaaagat acaaatgaag acttcgaaaa atctgttcaa
    38941 gagacaaagg cagctaagca agcttccaaa ggtgcccaag gtattcctca aggagctaca
    39001 ttctctggcg tacaaaaaat catttttgct tgtgatgcag gaatgggatc aagtgcgatg
    39061 ggcgcttcga tcttgagaaa aaaagtacag gaagcagact tgcctcaaac ggtgaccaat
    39121 caagcaatca gccaactgac agatgactcg aatacattga tcgttactca ggtcgaacta
    39181 caagaaagag caaaacaaaa agcaccgagc gcgcgttttg tctcagtaga aaactttttg
    39241 aattcacctc gatatgatga aatcattcaa gaattaagca gcaagcagaa aacatcagtt
    39301 tctgaaattg agaatgagcc agcagaagag tttctttcag caaacatcaa acaaatcaaa
    39361 gagattctac ttgtccacga tgatcgttcc ggatcagcaa caatggggat gaccgtgctc
    39421 aaagatatat tagacaagaa ccatttaact atcccgttaa gaaaagtcaa tatccaagat
    39481 ttaaaagatg aacctgattc actgatcgta gccaaagaaa gtttagcgga aaaagtacag
    39541 atggctgcac ctcaatccat tcatttatca gtcaacagca tggtcaatcc gcaaaaatac
    39601 gaatcgattg cacaatattt gaaacagaca gcttaaggga ggaaaacagc atgcaaagtt
    39661 tgccattcga catgatcgag ctcaatcgat cttttaaaac caaagaagaa gcgatccgct
    39721 attgcggtca gatgcttgta gaagcagggt gcgttgatga ggaatatatc gatgccatgg
    39781 tagatagaga caaaatgtta tctgtttata tggggaattt tatcgcgatt cctcatggaa
    39841 cagatgaagc aaaaaaatat gtgaaaaaat ccggcatctg tgtcgttcaa gtaccagatg
    39901 gtgtagattt tggtaccgaa gaagaagaaa agattgcgac tgttttgttc ggtattgcag
    39961 gagtcggaga tgagcatttg caacttgtac agcaaatcgc actttattgc agtgatatgg
    40021 acaatgttgt ccagctagca gacgcgctca gcaaagaaga agtaacggaa aatctagcaa
    40081 ttgcttaagg agagagaaaa atgagagcag tacattttgg tgcaggaaat atcggtcgag
    40141 gatttattgg agaggttttg gcagctaatg gatttgagat tactttcgta gatgtgaatc
    40201 acacgatcat tgatgcttta aatgaaagaa aagaatacga aatcgaatta gcagatgaat
    40261 caaaagaaaa aatcactgta aaaaatgtca aaggaatcaa caatcaaaca aatccagaaa
    40321 aagtaatcca agaaatcgct gaagcagatt tagttactac cgccattggc ccgaatatct
    40381 taccttttat tgctgagttg attgcaaaag gtatccaaga aagagaaaag gaaggaagca
    40441 caacatcttt agatatcatt gcctgtgaaa atatgattgg cggttcagca tttctagaaa
    40501 aagaagtgta taaatatctt ccggaaacat catttactga caaatatatc ggctttccaa
    40561 atgcagcagt cgatcgaatc gtcccattac aacaccatga agatccttta ttcgtccaag
    40621 tggaaccttt caaagaatgg gtcattgacg atagccaaag aaaaaataaa aaaatccaat
    40681 taaaaggggt tttatatgta gatgatctag aaccatatat cgaacgcaaa ctatttagtg
    40741 tcaatactgg tcatgcgact gtcgcttata caggtgcctt gttaggttac cagaccattg
    40801 atgaagcaat gcaagatgcg ttagttgtgg cacaattaaa atcagttttg caggaaacag
    40861 gaagtttgct gattgccaaa tgggggtttg atgcagagca gcatcatgcg tatattgaaa
    40921 aaatcattca tcgcttccaa aacaaaaata tctctgatgc gatcacacgt gtcgctcgga
    40981 caccattacg taagttaggt tatcaagaaa gatttacacg tccagtgaga gaactacaag
    41041 aacataactt gacttgccca catttgacgg caacaatggg gattattttt aattactatg
    41101 atcctgaaga tgaacaaagc cgtcaattgc atgaaatgaa gatccatgaa aacttggaac
    41161 aattgattca agaagtcaca ggaatcaatg atccgaaaac aatcgggaat atcaagcaaa
    41221 acgtgaaccg ttatgccaag caagtcgctt aaaataggat acgaaaaagg ggaatgtgac
    41281 gaaatttttg tcacattccc ctttttcgaa taactaggct gtttgtcctt caagataggg
    41341 cagatccaat tctttaccgt aacgttgttc taaagctagg cggatcaaac gagctgccag
    41401 gttctcattt cttgcaagga taggtccatg gaaataagaa ccgaagacat ttcggtaaat
    41461 gacaccttca gattggtctt caccattatt tccttgacct tgtaccactt tccccaaagg
    41521 tcgttcacct tcacctaaga aagtccgacc attgtggttt tcaaatccat aataagtttc
    41581 attgaattct tcgttatgga taacgatatc accgataaac cggttatttt cctgacttaa
    41641 cgtgtagtga tccagtgcac tgattccttg gatcttttct ccattagctc ccatgtagta
    41701 gtgacctagc aattggtagc caccacaaat ggctaacatg acgccatcat tttcgatata
    41761 gttgatcaaa gaatctttct ttttctggat gtcttttgaa atgattaatt gctcaaagtc
    41821 ttgaccaccg ccaaagaaaa ccaagtcata tttatcagca tcaaaaggtt catgtatact
    41881 aacgatctcc gtatggcaag aaacccccat tttttctgct atatatttca acatcaaaag
    41941 gtttccgtta tcaccatatg tgttcatcaa atttccataa aggtgggcga tattgagttc
    42001 ataattagcc acggttcatt cctcctttga taaatccttg agcagctagt tctttacgaa
    42061 gctgcaatac agcagtgtaa gtagctaaaa tatagacatg ctcagttggc aattctttga
    42121 ttttttcgat tacttctggt aattcttttg tttctgtcaa tttattttct ggaatcccgg
    42181 caacttttag acgtaaagtc atatctgtat gacggtctcc tccagaaata acagctggga
    42241 tatccatatc ggcaaagttt tcaaaattac catcccaaat ccagctgaca tcgattccgt
    42301 ctgcgtaatt ggcatttaat aaagccacta aagaaaatgg ataaggagct agaccaatca
    42361 tatcgattac ttgattgata cctacaggat ttttgacaag tactaatgta cattttttcc
    42421 cattgatatt gatgacttct tgtcggccga atactttctc gtcatatcct aaaccttgtt
    42481 tgattttatc aggatcgaca ttgaagtact ctgccactgc agtagctgct aaagcattgt
    42541 agacattata cataccgcca acttcgattc cgtattcatg accatcgatc acgaaatctg
    42601 ctgacacatt gtccatccgt accatatcag ttaatcgata atccaattca ggacgtttga
    42661 agtcacaatt tggacagtaa tatttcccta agtttgcata agtgatcatt ttataatgca
    42721 agatgtgatg acaatttgga cataagacac cgtctgtatt gtaatgagcc atttgttcac
    42781 gatcttcttc atggtcaaag ccataatatt ttctaggatt gactgtttcg atagaattga
    42841 agattggtga atcaccgtta ctgataatcg ttgcatttgg tgactttgcg gcaccgtcta
    42901 caatcatttt ataggtcgta tagatttctc cataccgatc catttgatca cggaaaatat
    42961 ttgtaaataa gaacagttct ggtttcatat attctgtgac tttgctcaaa cttgcttcat
    43021 ctatttctag gacagcaaac tttttctgtc ctttttttgg ttttgcctgc aagaaagtcg
    43081 atacaattcc ctgtaccata ttcgcaccag tagggttggt tagaacttca tcgaattgct
    43141 ggcgcaaaat attgactgtt aaagcggtag tcaatgtttt accgtttgtt ccggtgacaa
    43201 cgacgacttg gtagtctttt gccaaactat ctagtatatg tggatcgact ttcagcgcta
    43261 gtttacctgg taaacttgat ccgcctttaa aaaaagtttt taatgcccat tgcgacgttt
    43321 ttccaactgc aatcgcaaaa tgactgcgta ttcccattat gtaacctcca aaaacgattt
    43381 gctgacgaat aaattcaact aatcatacca tatgttgaaa aaaaggttaa attgcttttc
    43441 ttattcttaa gaaaaggtta cggctgaaag tgcatgaaat cggacaaaat cgcatgattt
    43501 aacaaaaaaa cagcttgaaa caaaatgatt gtttcaagct gctgtgattt tattattccc
    43561 tcttacctat attcccattt taaccgataa taattttctc gcttggatat tcatagccta
    43621 gatctcgtgt ttcttttggc acgaataaca tcaatgtata tagcattccg atccgcccaa
    43681 taaacatcag tgtagcaatc gtgattttgc ccacaacaga caagtctccg gtaatcccta
    43741 aagataaacc agttgttcca aacgcagaag ttacttcgat gatgatcgag atcagcgttt
    43801 gttcttctgt agcagataaa aaaacgatac aaaagaaaca cataccaaga gaaagcataa
    43861 agacaacgac tgattttcgc acatcatctt gatcgattct ccgtccaaaa atattgatgt
    43921 tatcttcact tttgaggaag gaatatagat acaaaccgat gattgctaca gtagttgttc
    43981 gaatcccgcc gcctacagaa ctaggactgc atccgataaa catcagtaaa gaaaaaatga
    44041 tcagtgttgt gatttgaaaa tcacccaaat cgtgaatctg cagaccagca ttacgagtcg
    44101 taatcgaata aaacatcgaa ttgatccatt tgacactcat attggaatct tggaataaat
    44161 ggtccttttc caatagataa atcaagacag ttcccgaaac aaacaagata acaaaagcta
    44221 acacagctaa tttggtaaac aaggaaaaac gaaacggaag cttcgcattg gaacgtttgt
    44281 ataatagcca ttcccggcac tccatcaata caggaaaacc aattcctccg acaaaaatca
    44341 aaaacatgat caggatcaag aaaaaatagt catgtgcaaa gggcttgatg gaatccccag
    44401 tgacgtcaaa cccagagttc gtgacagccg atatcgcctg ataaaaaccg taaaaaacgg
    44461 catcacgcca acgatcaaaa tagcctctgt aataaaaata aatagaaaag aatgtcccaa
    44521 aaagtaattg aaaccagatt aaaatagcaa aagtgatccg aatcagtcgg acgataccag
    44581 acaaacgcgg ttgattcata tccgtcatga tcagctgtcg ctgtttcagt gtgatccgtc
    44641 gtttagaaaa aatgacaaaa gcagtagaaa tcatcatgat ccccaaacca ccaacttgaa
    44701 ataatatttc cagcagtata ataccgttat cattgaacac agaattgata tcaaaagtcg
    44761 atagtccagt cacactcact gtactgattg ccatgaacag catgtccaca aaagaaacat
    44821 ggctatctgg ttcgcgaaaa atcggcatat aaaatagaac gagtgataag accgtcatca
    44881 atatataata aaaaacgatg atttggatcg atgagaaatg attggcagca aacttctgtc
    44941 ctcgccgctg cagccttcga aagaataaat caacatgcac agtactatcc tcctgacaat
    45001 agtcgtttct accagtatac aaggggaatt aggaatactc aaagaaatta tcaaacagat
    45061 aacaatacag ctttcgatta aaatagaaat ggcttataat aaggaaaatc ctagaaaaaa
    45121 gaaggaggag gaataacaaa ttgattaatg ctcaacaaat cgtagaaaaa atgaaaaatc
    45181 aaaaaataaa ttatgataca gttctgaaaa aaatgatcat gcaatgggag aaagaagaag
    45241 taaagcctaa gatattaata catacatgct gtgctccttg cagtacgcac acattggaat
    45301 tcatgtctca atatgcagag atcacgttat ttttttcaaa ttcgaatatt catcctaaaa
    45361 gtgagtattt gcgaagatta catgaacaaa aacgatttgt agaccaattt aatgagaaaa
    45421 ctgaccatca tgttgcgcta atcgttgatg aataccgtcc aaatgaattc accaaaatgg
    45481 ttttaacaaa ccatcttgaa aacgaaaaag aaggtggtgc tcgctgcagt gcatgcttca
    45541 atatgcgatt agatcttgtt gcgcaaaaag cgcaagaact aggatacgat tactttggaa
    45601 gtgccctgac catctcgcca aagaaaaatg cagctttgat caatcagatc ggaatggata
    45661 tccaaaagat ttacgggaca caatacttgc caagtgattt caagaaaaac aaaggctatg
    45721 aacgctcttt gcaaatgtgc aaagagtatg atatttatcg ccaatgttat tgtggttgcg
    45781 tgttcgctgc caagcagcaa ggatgcgatc tgaaagaaat caatcgggaa gcaaaagctt
    45841 acttaaaaac atcaaccgta gtttttgagg aaaattaaag aaatctttcg gaaaaacgta
    45901 agaaaaaaat aaagaattta tggtagaaat aaggtagact gtataatttg tccgtagtaa
    45961 agtaaggaaa caagaataaa tttcaatgaa ggaagagata agatgcgaaa agtagcacct
    46021 attttgaagc caatcgctgt attaacaatc tcgacgattg tcgcgactac tacaggtatt
    46081 gtgaatagtt ccagctaccg tgcaccaagt tcaagttcta gtactgtaga agaaacaaca
    46141 ccaactactt cagtctcgac atctgaacca acaacaacgg aaagtttgaa tgaaaccact
    46201 acgacaagta catgggacga tacaacaact agttcgtcgt atgatgagac atatacaact
    46261 gacagctcaa gcgaaacaag taatacggta ccagatggca ctccatcgga ttcaaccaat
    46321 ccaagtacaa gtccggatac aagtgctagc tccgaaacga taccaagcag tacgactgta
    46381 gatgataaca cgcaaaatga tgatgcagca cgtacagcac agcaaaacca agattcagga
    46441 aatacccaaa cgtataacca gcaagcaggt gattctcaat gacattttta ctagacctta
    46501 tcaacggggt gcataaattc cttggctatt tagacatcag tcctaaatat cttaaccgtg
    46561 gatatacgat tttaagtgtg attcccacgc tttatttatt gagaattgtt tatggacttt
    46621 ggcaaaacca aaactatctt caatttttct tatatggact tgcatttcta gtgcttgttt
    46681 attttactgt tttaaatgta ttttattact ttttagataa aaacacgaaa gccgatgtca
    46741 ctcagctttt tgtgaagtat ttacctgatg aagcgttcaa catccagaca gaagaatcga
    46801 tagataatgg aaattcgatc gataaagtga atacacaaga ggtcatggtt tcttatgacg
    46861 aagattatca attgaaatta gccgagaata tgcggtattt gattggaaat ggtgagatca
    46921 aaacaaatga actcggtcgc atggatggat ttctggtcga tagaaataca ttgtatcctt
    46981 attactatgt caagaaaaca ggagagaaag agtatgttct aaatattgga cgaagctact
    47041 cggacatgga aaaagtaggg accattcgac ttgactcaac agaagacaca ttggaacctg
    47101 tcggattgtt catcgtcggc ggtgattttg tcaaagacgg gttacgctat catgagcctt
    47161 atcgtctgaa attgattgca aaaaaggcac agtcgcagga agaaccagtg gtttatagtc
    47221 gtagccaaag aagaagacat tcataatgtg atgaaacgcc gtgtatcagt ggttgcgata
    47281 aaaacgttta ttcggaataa gggggatgtg acacgtcttt tgtcacgttc cttttttata
    47341 taacgagaaa gataagacga acacatcact tattctttcc tttcatttat aaacattgta
    47401 gaataaagaa agtacaacga agtattgtga aaaaacgtaa taaataacga ggaaaataca
    47461 agtaggaggt aagctgtgaa agaatttttg aaaaattggg ggattttgat ccttgtatta
    47521 gcggctattt tattagctag agtgtacgtg tttacaccag ttactgtaaa cgggcattcg
    47581 atggacccta cattaagtga tggacaacga ttgatttcat ctaagatctc aaactatgaa
    47641 cgaatggata ttattactac aaaggaaccg ggggatgaag aacggatgat tgttaaacgg
    47701 atcatcggta tgcctggaga tacagtcaag atggaaaatg accagttgac cattaatggc
    47761 aaaaagtatg atgaacctta tctggatgag ttcaaaaaag aattttcaga agataagtta
    47821 caaggagaat atgcttatag ctcaggattc caagcacaag cagaaagttc atccaccttt
    47881 acgagtgact ttgaatatac tgtgccaaaa ggaaagtatc ttgttctagg cgataaccgc
    47941 ttgatttcaa aagacagccg aatgtttggg ttagtcgaca aagatatgat ccaaggaaaa
    48001 gttgttttcc gttattggcc tctttcagaa attaaaatca tgtgatgaaa aaataaaaag
    48061 aagctgtgac atgttttttg tcacagcttc tttttccgaa aattccttct tatttcttgg
    48121 agttgctcac tttttttgca atctcatttt aagctttttg gctgatggat aagaaaagcg
    48181 aagcgttttt gttcataaat agcttttccc cacgatggaa ggtatgacta gtagcagaga
    48241 caaagcccgt tttttccaat cgattattca attcttcttg gctaaagcca ttatggactt
    48301 tcggatgact aatttgttca ttcttgtcaa agtctacgat gatcaattga ccgccaggag
    48361 ctaaaatttc ataaagtttt gtaagaatat tctccgtatc aggaatgtgt aaaagtacaa
    48421 gtgatagaag gatgagatta gcttggacag caggaaattc gacagaagca tcagcgtgga
    48481 tcgttcggac atttttcaga tctgctgctt ggatcttttc ttctgccatt ttcagcatag
    48541 tttctgaagc atcggcaatg atcagttctt tgaatctttc cgcaagcggt aaactaacaa
    48601 gcccagttcc gcctccgtaa tccagcagga ctttttggtg gctgtcgcgc ggtagataag
    48661 tagttagttc ttcgcgaata atcttggcta atgcttgacg gtcaggggaa tcataatggt
    48721 tagcgatgga atcaaaaata ttttttgtca tcaaatagct ccttacgtaa aactttgaaa
    48781 ttttaactta ttatagcacg tgaaaagaaa gaaagcatgc tatactcaat tcaaaaaggg
    48841 agaatctaga aagaatatgc cgatatcgtt tgtaaaagat agagaggaaa aaggaaagtg
    48901 tgtccgagaa atattactag acttgcctga gtggtttggg cttcctgaat caacggaaaa
    48961 atatatcgag gaatcaagta aactaccttt atggtgtgaa aaaagaaaag aagaatattt
    49021 aggctttatc actctttcac agacaagtga agatactgcc gaaatctatt ctattgtatg
    49081 ggaataaaaa aagactatca tcaccaagga ttaggaacaa aactttttaa agaagcagaa
    49141 ggttacgcag caaaacatta caaatatttg caagtgaaga ctgtagacga ggggcactac
    49201 tctatatatg atcaaactat ttgtttctac gaatcattag gattttcaag gttggaagtt
    49261 tttccaaatt tatgggatga atggaaccca tgtttagttc ttgtcaaaaa attggaacaa
    49321 aagtgagcaa tagatttaat actaatctgt gcttgatgaa aattctcact gtaaaaaatg
    49381 ctgaaaatca agtataatac cataggaaca aactggaagg tgaaaaagag catggcacaa
    49441 ctatttttta agtatggcgc aatgaatagc ggcaagacga tcgagatcct aaaagtcgca
    49501 cataattatg aagaacaaaa taagccagtt gtcttaatga caagcggtat tgatacaaga
    49561 gatggtttag gcgttgtttc aagccgaatc ggactgaaac gtaatgcgat gccgatattt
    49621 gaagaaacag acgtatttga cgtaattcag aaaatggaaa gcaaacccta ttgtgtgctg
    49681 atcgatgaag cgcaattctt aaaaaagaaa catgtcattg cttttacgag aattgtggac
    49741 gaattggata ttccggttat ggcatttggt ttgaaaaatg attttcgaaa cgagttattt
    49801 gaaggatcaa aatatttatt gctttatgca gacaaaatcg aagaaatgaa aacaatctgt
    49861 tggttctgcc acaaaaaagc aatcatgaat ttacattata ttgatggaaa ccctgtttat
    49921 gaaggcgatc aagtgcaaat tggcggaaat gaagcttatt accccgtttg tcgaaaacat
    49981 tactttcacc catcaatgat tacagaagga gaataagcat gtacgatcaa ttacaagcaa
    50041 ttgaagaccg ttatgaagag cttggagaac ttttaagtga cccagaagtg atttctgata
    50101 caaagcgttt tatgcagctt tcaaaagaag aagcaaacac gcgcgaaaca gtcgaagttt
    50161 atcgtcgtta taaagaagta gtacaaggaa tcaccgatac agaagaactg cttggtgaaa
    50221 aactggatga tgaaatggct gaactagcaa aagaagaatt atctgaatta aaaaaagaaa
    50281 aagaagtctt agaagaaaaa atcaagatct tgcttttacc aaaagatcca aatgacgata
    50341 aaaatatcat catggaaatc cgtggagcag caggcggaga cgaagcagca ttattcgctg
    50401 gcgatctttt caatatgtac caaaagtatg ctgaagcaca aggctggaaa acagaagtga
    50461 tggaagctaa cgttaccgga atcggtggat ataaagaagt gatcatgatg atcaccggag
    50521 acaacgtata ttcgaaatta aaatatgaaa gtggtgcgca ccgcgtccag cgtgttcctt
    50581 caactgaatc gcaagggcgt atccatactt ccaccgcaac agttgtcgtg atgccagaag
    50641 ctgaagaagt agagatcgat attgaagaca aagatatccg tacagatatc tatcatgctt
    50701 caggtgctgg cggacagcac gtcaataaaa cagcatctgc tgtacgtttg actcacttac
    50761 caacagggat cgttgttgct atgcaagatg aacgttctca aatcaagaac cgtgaaaaag
    50821 caatgaaaat cttgcgtgct cgtgtgtacg ataagatcca gcaagaagca caaagcgagt
    50881 atgatgccaa tcgaaaatca gcagtcggaa ctggggatcg ttcagaacgg atccggacgt
    50941 ataatttccc gcaaaatcgt gtgactgatc atcgtatcgg attaactatc caaaaattag
    51001 atcagatttt agcagggaaa ttagatgaga tcgttgatgc attgatcatg tatgatcaaa
    51061 catcaaaact ggaagctatg caaaatgggt aaaatgacct atcgagaagt cctgtcacgg
    51121 gcttcttctt ttttagagga tcatgggaaa gaagcatata gtatccaatt tttatttttg
    51181 gaacgaaaac aatggaaaaa acttgattgg ctccttcata tgaacgaaga gatttcagaa
    51241 gaagaacagc ggttgatcga aaccgatctg cgacttctgc ttgcagatca tccacctcag
    51301 tatttgctag gatatgcaga tttttatgat catcggttaa aggtaactga agcaacactg
    51361 atccctcgac cagaaacaga ggagttagtc gaatggtgtt tagacgagac gcctggtgta
    51421 ccgttagaag tgatagatat tgggacaggg actggagcaa ttgctattag tttgaaagca
    51481 gcaagaaaaa attggcatat atctgctgtg gatctttcag aagaagcatt agaagtagcg
    51541 aaagaaaatg ctcagaaaga aggaacgaaa atcagttttt atcatggaga tacattagga
    51601 ccagtaatgg atcagcaatt tgatgtgatt atttctaatc cgccgtacat cagtcggaat
    51661 gaatgggaac tgatggatga aagtgtccgg tcattcgaac ctaaaatggc cctttttgct
    51721 gagaacgatg gattagctat ttatgaaaaa atagcagttg aagcaccaag cgtactaaaa
    51781 tcaaatggaa agattttttt agaaatcgga tttcgccaag gtgaagcagt aaaaaaaata
    51841 tttcagcaag catttccaga taaaaaagtg gcgataaaaa aggatctttt tggcaatgaa
    51901 cgaatgatcc aagtttatgg ttgaagttgt ggatgaaaaa ttttttattt gtttttttat
    51961 tataaaaaaa cacttatttg acaaggatgt aaacgacttt ttggtttatc aacaagttta
    52021 tccactattg acaaatagat tatccacaaa cagtggaaaa cttgaggata aactcagaca
    52081 aaataagaat gtatgaaaaa ggggttgtgg ataaactgtg gaaacgaaac gatatgatga
    52141 aacagaattg caagaggcag ccgaagcact gaaagaagga gaacttgttg cttttcctac
    52201 cgaaacagta tacggattgg gcgccaacgc tcttttacca aacgctgtca agaaagtgtt
    52261 ttctgtaaaa gggagaccgc aagataatcc attaatcgtc catgtcgcct cttttgaaca
    52321 agtaaaagag tatgtggaca actttcatcc ggcagcagag aagattgtga agaacttctg
    52381 gcctggacca ttaactttga tatttaagat caaaaaagac actttgccct cagttgtgac
    52441 gggaggatta tccacagctg catttcgtat accggataac aaaaaaacac tagaagtaat
    52501 cgaactttcc ggtgttccgc ttgtcggtcc aagtgcaaat acgtcgggaa aaccaagtcc
    52561 aacgactgca gatcatgtat atcatgatct acaaggaaaa attaccggga ttattgatga
    52621 tggagctacg cgaattggtg tagaatccac tgttcttgat ttaagtgatc caacagccat
    52681 gcctatgatt ttacgaccag gtgcagtaac gaaagaacaa atcgaagcag tcatcgaatc
    52741 tcctgttgct attgatcagc atcttgtaaa agaaaatgaa acaccaaaag cccctgggat
    52801 gaaatacaaa cactactcac ccgatacacg tgttctgatg gtcagagatg gcgattggtc
    52861 aactgcagtt caatgggcaa aaaataagaa gatccgtgca ggtgtcatag caagccccga
    52921 aattgcggat caagtgcgga cagatactgc agctgtttat atgtataacg acaactcagt
    52981 agaagcggcg gctaaaggat tgtttgcagg tctaagagga ttagatgaac caacacttgg
    53041 attagatttg atttttgtac aagtgtatcc agaaactgga ttggggaatg cttacatgaa
    53101 tcgcttgaaa aaagcagcag gacaaaatta ttttgaaaaa tgatcaattg gttattgtcg
    53161 cattctttta gtatgataca atgctatcaa gtaaatcttc tatcagtgaa cgaaaaacta
    53221 agcgtaacta atcgtaatag aagagatacg aatatttggc aatttgtttt tgatgggaaa
    53281 aataaaattg taggaaaata aaaaggagct gttgtttgtg gtagattaca aaacgtttga
    53341 ccctgatctt tgggctgcga tcgccaaaga agaagaaaga caagaacata atttggagct
    53401 gattgcctct gaaaactttg tctccgaagc agtgatggct gcacaaggaa gtatcttgac
    53461 aaataaatac gcagaaggtt atccagggca tcgctattat ggtgggtgtg aatttgtcga
    53521 tatcgttgaa aatttagcga ttgaccgtgc aaaagaatta ttcggagcga aatttgcgaa
    53581 cgtccagcct cactccggct ctcaagccaa cacggctgct tatctcgctt tggtagaacc
    53641 aggggacacg atcttaggaa tggatctttc cgcaggcgga catctaacac atggatcacc
    53701 agtcaacttc agtggcaaaa cctatcactt tgttgcttac ggtgttgatc cgacaacaga
    53761 agttattgat tataatgtgg tacgtatttt agctagaaaa catcaaccaa aattgatcgt
    53821 agcaggtgcc agtgcttacg gacgaacgat cgactttgcg aaattcagag aaatcgcaga
    53881 tgaagtaggc gcaaaactga tggtagatat ggcacatatc gcaggattag tagcagcagg
    53941 acttcatcct aatccagttc cttatgcaga tatcacaacg actaccactc ataaaacatt
    54001 gcgtggccct cgaggcggca tgattttgac aaacgatgaa gcattagcaa aaaaaataaa
    54061 tagtgcggta tttcctggta ttcaaggcgg ccctctagag catgtgattg cgggtaaagc
    54121 agtagcattc aaagaagcat tagatcctgc atttaaagaa tatagtgaac aaatcatcgc
    54181 caatgcaaaa gcaatggtca aagttttcaa tcaagcaatt ggaaccagag tcatttcagg
    54241 ggcgacagat aatcatctga tgttgatcga tgttcgcgag ttaggtataa atggaaaaga
    54301 agcagagagc attttggaca gtgtgaatat cactgtaaat aaaaactcga ttccttttga
    54361 aacactaagt ccattcaaaa caagcggtat tcgaatcggc acgccagcaa tcactactcg
    54421 cgggttcaaa gaagaagatg ctgtaaaagt ggctgaacta gttgtcaaag cattacaagc
    54481 aaaagatgat aacgctcaac tagacgaagt caaaacaggt gtacgcgaat taactgaaaa
    54541 atttccgttg cataaaaaat aaaaatttaa attccattag taaacagaaa agttcaatgt
    54601 tgggcttttc tgtttatttt ttgggaaaac ggattctttg acaatatcgg tgatgctctc
    54661 tagtatatga ggtgtaattt tagtcttcac actaaatctc agggaggaaa agtcatgact
    54721 gatcgtatct cgttagaaaa ggaagcagta gcattcagtg atgcaaatgc gcctcatccg
    54781 cgtatctatg aactagcacc ggaagaagga agagttttac tagaagaagt acaagaatca
    54841 cctgtgaaca aatattccgt cgatattgaa gacttgatgg tggatactgg cgaatgggga
    54901 aaactcaata ttcgtctcgt acgaccagaa gggaatatgg ataaattacc agttattttt
    54961 tatattcatg gagcaggctg ggtttttggc agtgctcaaa cccatgataa attgatcaga
    55021 gaacttgcgg ttcgtacgaa ttccgtcgtt gtctttccag aatatagtcg atcaccagaa
    55081 gcaaaatatc caacagcaat tgaacaaaat tatgctgtgt tgcaacagct gaataaatta
    55141 gccaagtcaa aaaatctgga tctcgagaat ctaatcgttg caggagattc agtaggtggt
    55201 aacatggcta cagtcatgac gatcttaaca aaagaacgaa agggcctccc aatatccaag
    55261 caattgctgt attatccagt cacaaacgct gattttgata cagattccta tcatgaattc
    55321 ggagaaaact attttttgac aagagaagga atgatgtggt tttgggacca atatacgacg
    55381 aatgaagaag agcgtgctga aatcacagct tcgcctttga gagcaaatat aaatgaacta
    55441 aatgatcttc cttcagcaat gattttaacg ggagaagcgg atgtattaag agatgaaggt
    55501 gaggcttatg cgcgcaaact tcgtgatgca ggggttcctg ttacacaagt acgcttccaa
    55561 ggaatcatcc atgattttgt catggtaaat gctatggatc agacaaaggc aacgcgtgca
    55621 gcaatggcat tatctacttc ttggatcaag aaaaaagaat aagctttgct tgtccgcagg
    55681 aaaacttctt ttcaaaaacg gattttctta ggaaaaatgg cgagtttgac tagtcaatca
    55741 cttgattttg ttttacaatt aaaaagaaac gacagaacaa aggagagctt aaaaaatggg
    55801 caaatttcaa gtgatcgatc atccattgat tcaacacaaa ctaactatta ttcgggacaa
    55861 aaactgcgga acaaaggttt ttcgtgaagt agtcgatgaa atcgctatgt tgatggcata
    55921 tgaagtatca cgggatatgc cattggaaga catcgtgatc gaaacaccga tcactgaaac
    55981 aacacaaaaa acgttgtctg gtaaaaaagt agcgattatt ccaatcttgc gcgcaggtat
    56041 tggaatggtt gacggtatct tggaattgat tccagctgct aaagtgggac atatcggtct
    56101 ttatcgagat gaagaaacat tggaaccaca tgaatatttc gtcaaacttc cagaagacat
    56161 tgatgcacgt cagttgtttg tagtagatcc aatgttggca acaggcggat cagcaatcat
    56221 ggcaatcgat gcattgaaag aacgtggcgc gtcgaacatt aaatttgttt gtttggtagc
    56281 agcacctgag ggagtaaaag ctttgcaaga agcgcatcct gatattgaca tctatacagc
    56341 ttctctagat gaaaaattga atgaacatgg ttatatcgtt cctggactag gggatgcggg
    56401 tgaccgtttg tttggtacaa aataagtaaa tacgaaaaag ggtgtgacac aacttttgtc
    56461 acatcctttt ttggtcattt ttaacgtttg atgcagaaca gctttttcac agctttcgtt
    56521 tgcatataaa aaaaccatcc caaaaatgca gagatggtca aattcaaatc ttttttagtt
    56581 ctttgtagtt aacgattact acacccttac tttgcgtcat caagttcgca ttttctgcag
    56641 tttcatcaat ctcaacaaca gcggaatttt tcaattgctt tgaaatcgtt ccagtttgcg
    56701 acttgccgtg aattgtgaac attacgtgag tattgatctt gaatttttca ccaatttccg
    56761 atggtacgat agttgtatca aattttccaa aagttgccat tttcataaaa cctgcctttc
    56821 acatcaatta taccacgttt tatgaaaaat atcatgaaat taaactaatt ttccatcgga
    56881 ctctttacaa tcagccaaat agagtatata atttcttttg gataaggcca gcttagctca
    56941 gttggtagag caacgcactc gtaacgcgta ggtcgtaggt tcgatcccta tagctggcat
    57001 taaaagagaa gacagatata tcaaggattt ttaatccatt gatacatctg tctttttgtt
    57061 taaaggaaat aaagtatgct ttcttagcaa tagagcatgt attatttcta taaaaattta
    57121 ggagaataaa acgactagca atatagctgt gaaatcaaat atcacatgaa ctgcccaact
    57181 tgtaatgatc gagttgcttt taatggcagc ttggttgaat aacaatcttg ccaccccttg
    57241 tatcaaaagg atgtgtgcta cagtgtgtaa aatatttcca ttatcataag tactgtaatg
    57301 gataaatcca aagatgattg ctgacaagaa actagcgaca ggaatgctga acttactaga
    57361 aaaaatagcg agaaaataca ctgagaacaa ttcttctcca agtatcatga taggcaaaat
    57421 aataaataat aacgggctga aagcctcatt tattggattg cctgttaaac cccatttcaa
    57481 aatttgttgc aaaaataccg agactgcggc actgattact acattgataa aaaaatattt
    57541 ggctatattt ttgacaggag cgacaggttt cgagaacatt tttttcgtat cttttttacc
    57601 aaaaacaagt gtaaatgcta taaatccagt gatagttaaa gaaaaaatgc taataatgga
    57661 tggcgcaaat agcaacccta acaaaccgag tacaacgaca atagtgccca atatcccttt
    57721 tttaagttct attttttttc ctaaaatgtt attcatgata ataactccta ctattcagtt
    57781 tttgaagata gagtcagtat acatgaagag ttaaaatagg caatgttttt ttatggatat
    57841 ttgtattgct aaaaatttat cttatatatt cattttgatt atactacttt tatttgtaaa
    57901 aattttctag caaaaccaag tgcttgcaac tgattaagcg tacaattttt tagatgttcc
    57961 gagcgtactt caatcatttc aaaggagttg ctacttaaat cgatattttt taaatcagta
    58021 tcaaaaaagc tagcattttc taaatcatta gtagaaaaca ttattttagt gagggaacag
    58081 tctacaaaat ctgcgcttga taagacagag tgctcaaagg tactttcttt tatgtttgaa
    58141 ccagataaat ttacatagtc cattttacaa ttctcgaata acgtgttccc aatataactt
    58201 tccatcaatt tagtacctgt taatttacaa ttgacaaatt tcacgcgatg caacatgctt
    58261 tttgtcaata tacagcctga aaaatcacag ttttcgaata tacagtcggt aatctccatt
    58321 ctttgaaaat cattggaagc aaaaaatgca tacttgaaaa tagatttgta aataattgga
    58381 tggcagatta tttggttttc gatgacctct ttttgtgaaa ggatattata cagttcaaaa
    58441 tcttcgtttt catagatatg aaaaaaggat cctttattca agcttgcttc attaacttta
    58501 ggaaaaatca tatttaatta cctccatttt cataaagtca tattaacaaa agctaaacca
    58561 acttacatta gcagaaaatg agataggttt tcgccttttt cgataacgat agtgtcgcta
    58621 tctcttgaaa cgttcttaga attgccctga gagacacaaa ttaggcgtaa ttctaataaa
    58681 aatcttagaa taaaaatttt tactgattta atttagaatg tttttaa
//
LOCUS       DAZKKZ010000010        55502 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.010, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000010 DAZKKZ010000000
VERSION     DAZKKZ010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 55502)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 55502)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..55502
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.010"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            558..3197
                     /locus_tag="ACG8LA_000655"
     CDS             558..3197
                     /locus_tag="ACG8LA_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HFQ0202981.1"
                     /translation="MEEYKQTIEEVKKVTEADPDTGLSSQEVDERRKKQGLNKFDEAP
                     KESMIKKFFRSLSDFTTIILLVAAVISFYTAFATEHGDLFEGLLIIAIVVINSVLAIV
                     QEGNAEKALESLQDMNKQTATVIRDGKVTTVESEQLVVGDILVLESGDAISADARLIE
                     ASQLRVEESALTGESEAVEKDAAFIAEEDESLGDQLNMVFKGCTVAAGRGKAIVTAIG
                     MATEMGKIADLLNENTMQKTPLQVRLNQLGKRISMIALAAAALVFVIGELQGEPLLEM
                     FMTSISLAVAAVPETLTVIVTLTLAYGVQKMARKHAIIRQLPAVETLGTANVICSDKT
                     GTLTQNEMRVRRVWSKEDEVTNIEDSMTNSAMEILKMAALCTDVTVEQEDDDLVIKGN
                     PTEVAIVRAVEENYHTKAELEEKYPRVNELPFDSERKMMTTVHQMGEKYISITKGAFD
                     VLAPRFSSGDVEQAAIVNDRFGKRALRVIAVGYATYDEEPQDISSEALEKDLRLIGLI
                     GMIDPPRPESKGAIKRAKKAGIKTVMITGDHVVTASAIAKELGILNDPSEALSGSELH
                     QLSDEELDARVKALSVYARVTPEDKIRIVKSWQRTGAVVAMTGDGVNDAPALKASNVG
                     CAMGITGTDVAQSAADMILTDDNFATIVDAVSQGRSVYQNIRKAINFLLSCNISEIFI
                     VLIAMLLGWGAPFTAVQLLFVNVVADGLPGFALGREPAEHGIMDQPPIPKNEGIFARG
                     LLQKIAINAGVFTIVTLFGYYLGSYVDTISPWVDASQHVGQTVAFLILAYSSILHVFN
                     VRSSQSIFKVNLATNKALVEMALLALAITTAVALLPFTQELFGLVHISLNHWFLVGIL
                     SIVPIAVNELIKFHRLPEAEEEE"
     gene            complement(3365..4063)
                     /locus_tag="ACG8LA_000656"
     CDS             complement(3365..4063)
                     /locus_tag="ACG8LA_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HFQ0202982.1"
                     /translation="MQSSAELKRQAKESLKGRWGQAVLLNLIPTLIGIATILLIMIPI
                     ILFATTIYDGSASVSEATTSGGGSSGGGGGIISSIISALFMSGISWTYLDILRGQKDQ
                     IEPFKDAFRGFKGLFIGGVISLAVLISIFTTLWGLLLVIPGIIKSYSYSQSYFIYYDI
                     VQETGQTPKVLDTITASRKLMDGYKGQLFWLDLSFIGWHILALATAGIGYLWLSPYIS
                     ATKAAFYEQLPKDI"
     gene            4281..5426
                     /gene="tgt"
                     /locus_tag="ACG8LA_000657"
     CDS             4281..5426
                     /gene="tgt"
                     /locus_tag="ACG8LA_000657"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008479 - tRNA-guanosine(34) queuine
                     transglycosylase activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HFQ0202983.1"
                     /translation="MTQPAIRYRLIKKEKHTGARLGELITPHGTFPTPMFMPVGTLAT
                     VKTMSPEELKEMGAGVILSNTYHLWLRPGEDLVEEAGGLHKFMNWDQPILTDSGGFQV
                     FSLSDMRNIEEEGVHFKNHLNGSRMFLSPEKAINIQNKLGSDIMMSFDECPPFDESYD
                     YVKKSVERTSRWAERGLKAHANPDRQGLFGIIQGAGFEDLRRQSAKDLVGMDFPGYSI
                     GGLSVGEPKSEMNRVLEFTTPLIPENKPRYLMGVGAADSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAKYAHDFRPIDEKCDCYTCKNYTRAYIRHLIKCDETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREAFFEEYGFNKENAKSF"
     gene            5523..5903
                     /gene="yajC"
                     /locus_tag="ACG8LA_000658"
     CDS             5523..5903
                     /gene="yajC"
                     /locus_tag="ACG8LA_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HFQ0202984.1"
                     /translation="MGTLPMLVMFIALLAMWFFMSRSQKKQQQERQNLLDSMKPGDSV
                     VTIGGLHGVVSEIDNDKRTVVLDCEGIFLEYDRAAIKTVKPGTVVTNDATTTVETTEE
                     PAETVEVKTETTETLEETEEKEEK"
     gene            6208..8805
                     /gene="adhE"
                     /locus_tag="ACG8LA_000659"
                     /gene_synonym="adhC"
     CDS             6208..8805
                     /gene="adhE"
                     /locus_tag="ACG8LA_000659"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004022 - alcohol dehydrogenase (NAD+)
                     activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006066 - alcohol metabolic process
                     [Evidence IEA];
                     GO_process: GO:0015976 - carbon utilization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HFQ0202985.1"
                     /translation="MAKVIEKEKTKTIDVQAMIDDLAEKANAALKEMESFDQEKVDHI
                     VHEMAMAALDQHMPLAKMAVEETGRGVYEDKAIKNMYASEYIWHNIKHDKTVGVINED
                     VQKGLIEIAEPVGVVCGVTPTTNPTSTTIFKSMIALKTRNPIVFAFHPSAQKSSAEAA
                     RVVRDAAIAAGAPENCIQWIEHPSIEATSMLMNHPGIAIVLATGGAGMVKSAYSTGKP
                     ALGVGPGNVPAYIEKTAKIKRAVNDLIVSKTFDNGMICASEQAVIVDKEIYAAVKAEF
                     QAHQVYIVKPDELQKLEDAVMNEGKYAVNPSIVGHSAMEIAKLAGISVPKGTKMLIAE
                     LEGVGPDYPLSREKLSPVLAMIKANNTDHAFDLCEGMLNLGGLGHTAVIHSENEELHV
                     KFGLRMKACRILVNTPSAEGGIGDIYNEMIPSLTLGCGSYGKNSVSRNVSAVNLINVK
                     TVAKRRNNMQWFKLPPKIFFEKNSLLYLEKMENVERVMIVCDPGMVQFGYCDTVREVL
                     ARRKNDVKIEVFSDVEPNPSTNTVYAGTKLMADFKPDTVIALGGGSAMDAAKGMWMFY
                     EHPDTSFFGAKQKFLDIRKRTYKIDKPEKTQFVCIPTTSGTGSEVTPFAVITDSETHV
                     KYPLADYALTPDVAIVDPQFVMSVPASVTADTGMDVLTHAIESYVSVMASDYTRGLSL
                     QAIKLVFDYLEKSVKTPDMESREKMHNASTMAGMAFANAFLGICHSVAHKIGGEYGIP
                     HGRTNAILLPHIIRYNAKDPQKHAMFPKYDYFRADTDYADIAKFLGLKGETTEELVEA
                     LATAVYELGKSVGINMSLKAQGVTQETLDTTVDRMAELAYEDQCTTANPKEPLISELK
                     QIIIDAYNG"
     gene            9034..10140
                     /locus_tag="ACG8LA_000660"
     CDS             9034..10140
                     /locus_tag="ACG8LA_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HFQ0202986.1"
                     /translation="MIIKEEIFVPKELVKEKIDLLVENLTTIKDDNGEFLLDFDGLKV
                     DDKSWTVWNWPQGVGLYGIYKNYQMTKNPRAYQVVNEWFEDRMEEGAPPKNVNTMAPL
                     LTMAYLYEDTKDSRYLPYLEQWAEWVMNDMPRTNEDGLQHATYGPENKNQLWDDTLMM
                     TVLPLAKIGKLLNRPEYLEEARYQFMIHIKYLMDKRTGLWYHGWTFEGNHNYAEAFWA
                     RGNCWLTIAIPEIIEILELSKEDALRKLLIETLEAQVRALKTYQSESGLWHTLLDDPS
                     SYVESSATAGFAYGILKAVHKRYLPQEYKEVAYRAIQGLLEQIDEKGEVQNVSIGTGM
                     GDSLDFYRNIGITAMPYGQSLTVLCLTELLVSYC"
     gene            10157..11185
                     /locus_tag="ACG8LA_000661"
     CDS             10157..11185
                     /locus_tag="ACG8LA_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter substrate-binding protein"
                     /protein_id="HFQ0202987.1"
                     /translation="MKKTSLLFAASSLSLGLLGLSGCGNNSSVATVADADVNEIVTLR
                     FAYASNSQPVIDAMNEFGRLVKEKTDGSVQIQYFPDGQLGGERELIELTQSGAVDFTK
                     VSASALESFSKDYSIFSVPYLFNDEEHFFKVMDNEEIMEPIYQSTKNLGFTGLTYYDS
                     GQRSFYMVDGPIHTPEDLEGKKIRVMQSETAIKMVELLGGSPVPMGSDEVYTSLQSNL
                     INGSENNEFVLYTAGHGGVAKYYSYDEHTRVPDIIIMNDAIKEQLTDEQEKAIEEAAK
                     ESTVFEIEAFAKAIEEEKALAQEEHGVQFNDVDNTPFREAVAPLHDIFKNDPTYKDLY
                     QKIQEQGA"
     gene            11191..11670
                     /locus_tag="ACG8LA_000662"
     CDS             11191..11670
                     /locus_tag="ACG8LA_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter small permease"
                     /protein_id="HFQ0202988.1"
                     /translation="MKMILNKVLEILGAVLLVGMVAVVLWQVFSRTVLGNPNTVTEEL
                     VRFGLVWFAMLSSAYVVGQKAHLAVTVLSEKLTGKKSKILEVVVQSLFLVFAAMIMVY
                     GGWNAVTLTMGQISPSLSIPMGYVYLSVPVSGVLIIIYSLINLIDTLSNKPAIQEKI"
     gene            11686..12981
                     /locus_tag="ACG8LA_000663"
     CDS             11686..12981
                     /locus_tag="ACG8LA_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0031317 - tripartite ATP-independent
                     periplasmic transporter complex [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter large permease"
                     /protein_id="HFQ0202989.1"
                     /translation="MAIEAGLVLFFVFVVLLVLGMPIAISIAFSSMMTLLLVIPFDVS
                     AFSSAQKMVGSINSFSLIAIPFFVLSGIIMNNGGIAKKLVDFAMLFVGRVPGALAHTN
                     VLGNALFGSISSSAIAASTAIGGVLIPQQVEEGYDRKFATAVNIASAPTGMVIPPSTA
                     FIMYSLVAGGASISALFMGGYLVGALWALGIMLVAFIVAKKNKYPVVEKGQMAHAGKI
                     IKEAIPSLLLIVIIIGGILTGIFTAVEASAIAVIYSLLIAMFYYKTVKLKDIPNMLFQ
                     SVAMSGTIMFLLATSSMMSFAMAFTGIPQAISSLIMGVTDNKFIILLLVNLVLLLVGM
                     FMDVAPAILIFTPIFLPIVTSVGVDPVHYGLFSIMNLCVGSITPPVGTGLYVGASVGG
                     VKAEAMLKPLLPFYGVILVVLFLITYFPQIVMWLPNMLS"
     gene            12992..13816
                     /locus_tag="ACG8LA_000664"
     CDS             12992..13816
                     /locus_tag="ACG8LA_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase family
                     protein"
                     /protein_id="HFQ0202990.1"
                     /translation="MLNITIRGHDLSEVQTIEDLAEKTKEQGIHTLQLALGLSFPETP
                     SGANEINSGMGNYVKRVLEKQEVTVGILSCYINMIHPDLTIRQELLTKFEQYLRYASS
                     FGASMVASETGCVLPEIQYTEENFTDEAFAEAVSVIRRLVKAGEKYQMMVGIEPGLNH
                     PVYSLARVEQLIQAVDSDYLGIILDPTNLITSSDYQEQVQLVEEAFERFGEKICAVHL
                     KDFRVEQEKIVPVNLGDGVIEYTKIKEIIMKNRPYLYVVLEETKDDGIRYGRSLLE"
     gene            13981..14880
                     /locus_tag="ACG8LA_000665"
     CDS             13981..14880
                     /locus_tag="ACG8LA_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0202991.1"
                     /translation="MLQKKISGEQVNTMVSDQYEIYHVKDVVSQNKTIYHHHDFYEIH
                     ATLKGEATFYLNGRQFTIKAGSVLLIHSNDLHRIVRQSSDVFERVYIFVTPSFLESRS
                     TPWSNLSACFQPMGEKRSRVLQIEQEVLKQKLSFIDHPPDKKIYGEDIKYEQALVEYL
                     IFLNQVVQKEESAQEQNAVVPNERVEQMLQYISKNLSHPLSLEEMEKQFFVSKYHITR
                     EFKKYTGFTFHQYVMKKKLIYAKHLLREYRSSSAVYSKSGFSSYPHFLKAFKREFGIT
                     PKEFLKRDTQKQLVHYEHFEDEQ"
     gene            complement(15006..15875)
                     /locus_tag="ACG8LA_000666"
     CDS             complement(15006..15875)
                     /locus_tag="ACG8LA_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HFQ0202992.1"
                     /translation="MDYWEKANHSWSEDSKRVILTPTQRSRNLFFYIQEIGYFKAPIP
                     YYTERAHLPSYLIKFTLSGKGSLTYNDNQQQLKAGDLFFIDCQEYQRYQTISEEPWEM
                     DWIHLNGQNVQSFYQEFTKDGHNTFHSTGDPSENKIHHLITELIHMQQGTNARTDFQS
                     SVAIHELLNELILQKYQLDFEEEDIPAYVYKLKQYLDEHFKETITLDQLEQQFLLNKY
                     QLSKDFSKFIGSPPIDYLISKKLSYAKDLLRYTEFTVRMISEEIGIENFAYFSRLFKA
                     KTGLSPRDFRKFS"
     gene            16028..17488
                     /gene="rhaB"
                     /locus_tag="ACG8LA_000667"
     CDS             16028..17488
                     /gene="rhaB"
                     /locus_tag="ACG8LA_000667"
                     /EC_number="2.7.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008993 - rhamnulokinase activity
                     [Evidence IEA];
                     GO_process: GO:0019301 - rhamnose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HFQ0202993.1"
                     /translation="MNPTFVAIDIGASSGRLMKSTRDAKGSLILEEVHRFKNGFRNKD
                     GHDRWKIDYLIKEILIGFEKLKQTGIDRLFAGIDTWAVDYCLIDEQGDRINDPIAYRD
                     KRTNGAVEQFSEIYSLDKLYEQTGIQIQPFNTLFQLFAEEKENLAKAHKLLLIPDYLG
                     YVFTGNMVTEKTNASTMQLLNAGTKEWEIELLEKIGVSKELFPPLTEPGTILGDLQKE
                     QFSKYDLPDVTFITVASHDTASAVLGTPGQGERWGYISSGTWSLLGIETKIANVSRNA
                     FSENYTNEWGAHNTVRFLKNIMGMWLIQEVARMQEYEYSYAELAELAAKEKPLQQVME
                     INDPRFLNPPNMIEEIQQYCFETEQPVPVSSGAIARCVYDNLALCYAQELIKVEHLTG
                     TKLEKLHIVGGGSNNRLLNQLTADYAGIIVEAGPSEATAIGNVAMQMLSTGQFSNIEQ
                     ARNVIKQSFPCETFYPDENKQNTMEWYVNKIKGVIV"
     gene            17485..18741
                     /gene="rhaA"
                     /locus_tag="ACG8LA_000668"
     CDS             17485..18741
                     /gene="rhaA"
                     /locus_tag="ACG8LA_000668"
                     /EC_number="5.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008740 - L-rhamnose isomerase activity
                     [Evidence IEA];
                     GO_function: GO:0030145 - manganese ion binding [Evidence
                     IEA];
                     GO_process: GO:0019299 - rhamnose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose isomerase"
                     /protein_id="HFQ0202994.1"
                     /translation="MNTIERNYEQAKEKYATIGVDTDAVLEKIQDIKISMHCWQGDDV
                     KGFLTPDGELTGGIMATGNFPGAARTPEELRQDLEKAYSLIPGKHKLNLHAIYLDTEE
                     SVDLNEIEPKHFEKWVEWAKKEEIGLDFNPTFFSHPMMKDGFTLAHPDKEVREYWIEH
                     GKRSRKIAEYFGKETGQTSINNFWVPDGMKDNPIDRFTPRERLMESLDEIFTEELDER
                     YVQDAVESKLFGLGAEAYTVGSHEFYMGYGLTRDKLVCLDAGHFHPTEVISNKLSSLA
                     LFSKGIMLHVSRPVRWDSDHVVLMDDELQEIAKELVRNELLEKTNIGLDFFDATINRI
                     AAWVIGTRNTQKALLKAMLEPVERLKEMELAFDFTSRMAYTEELKDFPYADVWNYFCY
                     KNQVPVGLDWLEEVQEYQKDVLELRK"
     gene            18755..19600
                     /gene="rhaD"
                     /locus_tag="ACG8LA_000669"
     CDS             18755..19600
                     /gene="rhaD"
                     /locus_tag="ACG8LA_000669"
                     /EC_number="4.1.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008994 - rhamnulose-1-phosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0019301 - rhamnose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulose-1-phosphate aldolase"
                     /protein_id="HFQ0202995.1"
                     /translation="MKKIDILQAPYVKEMIETTSNLYRLGWDERNGGNISYLLKEEEI
                     TPFLDPEKVIRRISMIFDASRLAGCYFIVTGSGRYFKNVASEPAENLGIVRVAEDGKT
                     LELLWGLENECLPTSELPSHFMSHIARLEVDPDNRIVMHCHASHLLAMSFTHELDERS
                     FSRTLWQMCTECLVVFPEGISIIPWMVPGTNEIGEATAEKMKETRLVLWPQHGIYGSG
                     KDMDEVFGLIETAEKAAEVYTYVKAQGPILQTITDENLWHLADAFGVTPKAGYLEEVH
                     TKAGV"
     gene            19602..19913
                     /gene="rhaM"
                     /locus_tag="ACG8LA_000670"
     CDS             19602..19913
                     /gene="rhaM"
                     /locus_tag="ACG8LA_000670"
                     /EC_number="5.1.3.32"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0062192 - L-rhamnose mutarotase activity
                     [Evidence IEA];
                     GO_process: GO:0019299 - rhamnose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose mutarotase"
                     /protein_id="HFQ0202996.1"
                     /translation="MVKKAFCMKVYPEKQEEYKKRHDELWPEMRTALREHGVIDYSIY
                     LDPSTSLLFGYLVIEDEKLWEKMANTSINQKWWKYMEDIMETNPDASPVSWELMPVFE
                     L"
     gene            19995..21146
                     /gene="fucO"
                     /locus_tag="ACG8LA_000671"
     CDS             19995..21146
                     /gene="fucO"
                     /locus_tag="ACG8LA_000671"
                     /EC_number="1.1.1.77"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008912 - lactaldehyde reductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lactaldehyde reductase"
                     /protein_id="HFQ0202997.1"
                     /translation="MSNRMILNETSYFGKGAIESIVPEFQQRGFGKAAVITDKGLIEH
                     GIATKVTELLDKAAIAYALYDGIVPNPTIQNVKDGVAFVKEAEADCLIAIGGGSPIDT
                     AKAIGIILTNPEFSDVISLEGVADTKNPCLPILAIPTTSGTAAEVTINYVITDEVNHR
                     KFVCVDPHDIPIVAFIDSDMMMGMPKKLAASTGMDAMTHAIEGFITKGAWEMTDMLHL
                     KAIEIIGHSLEVSVDGDQNGREKMALGQYIAGMGFSNVGLGLVHGMAHPLSAWYNIPH
                     GVACAALLPTVMKYNKEYTGEKYREIALVLGIKGAAEMSLEDVREAACGEIDRLSKAV
                     GIPETISELGVKEADIPAIAEDALRDVCTPGNPRETTVEEIIALYQSLM"
     gene            21273..22031
                     /locus_tag="ACG8LA_000672"
     CDS             21273..22031
                     /locus_tag="ACG8LA_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HFQ0202998.1"
                     /translation="MENKKPYGTVLIKASKILDYLAENQDVSLQTIAKGVGMTSSTVL
                     KILDTLLMIGYVNKNSEKNYRLGAKLIRYANKNIEQIDLVELTLPFLEQLQQKIDETI
                     HLGVLDNNEILYVNKLDPKHQTIRMSSKIGITRPLYNSAMGKAVLAEFSEEQYTDYLE
                     KHPLIPYTEYTITNALRLKKEIQTVKETHIAFDDEEIERDIFCIGASIVKNEQIIGAF
                     SVSMPKYRLTDETKEQIISALKQTKSEIEQRIQK"
     gene            22131..22775
                     /locus_tag="ACG8LA_000673"
     CDS             22131..22775
                     /locus_tag="ACG8LA_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HFQ0202999.1"
                     /translation="MKKIDILSRLKNAGVIAVVRGKSKEEALNACHAIIKGGLTGIEL
                     TFTVPQADQVIKELLSFYKDQPEIVIGAGTVLDAVTARLAILAGAEYIVSPSFDQETA
                     EMCNLYQIPYLPGCMTITEIKTALKSGVDIVKLFPGSAYGPSIISAFKAPMPQVNIMP
                     TGGVSLDNMKEWFDAGVVTVGVGGNLLAPAATGDFDKVTEVAQQYAAKMKEIKR"
     gene            22782..23789
                     /locus_tag="ACG8LA_000674"
     CDS             22782..23789
                     /locus_tag="ACG8LA_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PfkB family carbohydrate kinase"
                     /protein_id="HFQ0203000.1"
                     /translation="MGKVVTLGEIMLRLSTEQGTRIDSSERFAAHYGGGEANVAISLA
                     NYGHEAIFATKVPDNALGKAVKKHLQCYGVDTKQVLSGGSRLGTYYMETGSGERAASV
                     IYDRAGSSFAEMDHLEWSLEELFQGIDIFHVSGITPALSKKWQKMTKQVIEAAKKAGC
                     LISFDINYRGKLWTQQEASEVIHQLLPLVDICSAGKMDALYLLGIEKAPEAEEQPLIY
                     YYQKMQEKFPNIQVFYSTKRTVHSASENELKGTLWMNHEYVESQVHRITPIVDRVGGG
                     DAFAGGVLHGILSNMSPQEIIDFATAASALKHTIHGDCNQFSQEEVAQFLACGSGKII
                     R"
     gene            23805..24647
                     /gene="kduI"
                     /locus_tag="ACG8LA_000675"
     CDS             23805..24647
                     /gene="kduI"
                     /locus_tag="ACG8LA_000675"
                     /EC_number="5.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008697 -
                     4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0045490 - pectin catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-dehydro-4-deoxy-D-glucuronate isomerase"
                     /protein_id="HFQ0203001.1"
                     /translation="MQEMETRYTHSPEDIRHYSTEQLRKEFLVEKVFEPGKISLTYTH
                     NDRMIFGGVTPTEKELEITLDKELGVDYFLERRELGVINIGGPGFIEIDGQKEEMKKQ
                     DGYYIGKETRHVVFSSQDAENPAKFYISSVPAHHKYPNVKISIDQVKPMETGEGLTLN
                     ERKIYQYIHPNVCESCQLQMGYTILEPGSAWNTMPCHTHERRMEAYVYFDYANEDTRV
                     FHMMGKPDETKHLVVDNEQAIISPSWSIHSGVGTSNYSFIWAMCGENITYTDMDMVQM
                     DQLK"
     gene            24667..25470
                     /locus_tag="ACG8LA_000676"
     CDS             24667..25470
                     /locus_tag="ACG8LA_000676"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HFQ0203002.1"
                     /translation="MEFSMDMFRLDGKVALVTGAVYGIGFEIARSLATAGAKIVFNNL
                     NQESVDEGIAHYKEAGIDAKGYVCDVTDEEAVQAMVQQIKEDVGSVDILVNNAGIIKR
                     TPMIEMDAADFRQVIDVDLNAPFIVSKAVIPDMIEKGGGKIINICSMMSELGRETVSA
                     YAAAKGGLKMLTKNIASEYGQYNIQCNGIGPGYIATPQTAPLRETQENGERHPFDQFI
                     VGRTPAARWGEPIDLAGPSVFLASSASDFVNGHVLYVDGGILAYIGKQP"
     gene            complement(25719..26783)
                     /gene="fni"
                     /locus_tag="ACG8LA_000677"
     CDS             complement(25719..26783)
                     /gene="fni"
                     /locus_tag="ACG8LA_000677"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004452 - isopentenyl-diphosphate
                     delta-isomerase activity [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HFQ0203003.1"
                     /translation="MNRKDEHVSLAKAFHDKQKNEFDFVRIIHNPLPQIAVSDVDLST
                     QAVGFTLSSPFYINAMTGGSEKTKKINQDLAIVAREADLMIATGSVSAALKVPSLADT
                     YTIMRQEYPHGKIIANIGAGTSVERAKEAIRLFHADALQIHLNAPQELVMPEGDRDFT
                     NWKVLIQETQTAIDVPLIVKEVGFGMTRETLNDLAALGVHTVDISGRSGTSFTQIENA
                     RRSKRELSYLADWGQSTVSSLLEANEADTSMEILASGGIRNAYDIFKALCLGANAVGT
                     SGTVLTHLMNHGVEETIILMKQWQEELRLLYTMVGATNTAALHQQSLIFSGPVKDWCE
                     ARGIDLVKYGRRTEKSVGQK"
     gene            complement(26780..27865)
                     /locus_tag="ACG8LA_000678"
     CDS             complement(26780..27865)
                     /locus_tag="ACG8LA_000678"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004631 - phosphomevalonate kinase
                     activity [Evidence IEA];
                     GO_process: GO:0016126 - sterol biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HFQ0203004.1"
                     /translation="MIEVSAPGKLYIAGEYAVVETGHPAVIAAVDQFVTVTVESARKV
                     GSIQSAQYSGMPVRWTRRNGELVLDIRENPFHYILAAIRLTEKYAQEKNILLSFYDLK
                     VTSELDSSNGRKYGLGSSGAVTVATVKALNVFYALNLSQLEIFKIAALANLAVQDNGS
                     CGDIAASCYGGWIAFSTFDHPWLQEQETQHSISELLALDWPGLSIEPLIAPEDLRLLI
                     GWTGSPASTSDLVDQVHRSREDKMVAYQLFLKNSTECVNEMIKGFKENNVTLIQQMIR
                     KNRQLLHDLSAITGVVIETPALNKLCNLAEQYEGAAKSSGAGGGDCGIVIVDQKSGIL
                     PLMSAWEKAEITPLPLHVYSDQRKENR"
     gene            complement(27878..28855)
                     /gene="mvaD"
                     /locus_tag="ACG8LA_000679"
     CDS             complement(27878..28855)
                     /gene="mvaD"
                     /locus_tag="ACG8LA_000679"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0004163 - diphosphomevalonate
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HFQ0203005.1"
                     /translation="MFKGKARAYTNIALIKYWGKKNEELILPMNNSLSLTLDAFYTET
                     EVIFSDSYMVDEFYLDGTLQDEKATKKVSQFLDLFRKEAGLSLKASVISQNFVPTAAG
                     LASSASGLAALAGACNTALKLGLDDLSLSRFARRGSGSACRSIFGGFVEWEKGHDDLS
                     SYAKPVPSDSFEDDLAMVFVLINDQKKEVSSRNGMRRTVETSSFYQGWLDSVEGDLYQ
                     LKQAIKTKDFQLLGETMERNGLKMHGTTLAAQPPFTYWSPDSLKAMDAVRQLRKQGIP
                     CYFTMDAGPNVKVLVENSHLSEVQETFTKLFSKEQVITAHAGPGIAIIE"
     gene            complement(28848..29792)
                     /gene="mvk"
                     /locus_tag="ACG8LA_000680"
     CDS             complement(28848..29792)
                     /gene="mvk"
                     /locus_tag="ACG8LA_000680"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004496 - mevalonate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0016126 - sterol biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HFQ0203006.1"
                     /translation="MANYGQGESSGKIILMGEHAVVYGEPAIAFPFYATKVTAFLEEL
                     DAMDDQLVSSYYSGNLAEAPHALKNIKKLFIHLKKQHDIQKNLQLTIESTIPAERGMG
                     SSAAVATAVTRAFYDYLAFPLSREILLENVQLSEKIAHGNPSGIDAAATSSLQPIYFT
                     KGHPFDYFSLNIDAFLIVADTGIKGQTREAVKDVAHLFETQPHETGQMIQKLGYLTKQ
                     AKQAIIENSPETLAQTMDESQSLLEKLTISNDFLNLLIQTAKDTGALGAKLTGGGRGG
                     CMIALAQTKTKAQEISQALEDAGAAETWIQGLGVHTYV"
     gene            30108..30767
                     /locus_tag="ACG8LA_000681"
     CDS             30108..30767
                     /locus_tag="ACG8LA_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HFQ0203007.1"
                     /translation="MSVIVLAGTIGAGKSSLTEMMAEHFDSQAFYESIDDNEVLPLFY
                     ANPEQYAFLLQIYFLNKRFASIKQAMKDDNNVLDRSIYEDSLLFHLNADLGRATETEV
                     RVYDELLENMMEELPYAAHKKHPDLLVHIRVSFDTMLERIEKRGRSYEQLSFDPSLYD
                     YYKELNRRYDQWYEEYKESPKIQIDGDRYNFVEDPQAKEEVLKMIEEKLAEIRQTKVA
                     I"
     gene            30852..31757
                     /locus_tag="ACG8LA_000682"
     CDS             30852..31757
                     /locus_tag="ACG8LA_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HFQ0203008.1"
                     /translation="MREKHYFNQDRNFWINVQQNDVLAVKNLKEEYGISDEMLTYSLD
                     KNERARVEYDSFDEALLLVSNVPHQQKVDNHYETSPIAFILKEDGLFTFTTPNTEYVI
                     RLIRSLLERMPDMSVYSLLFRTLFLISDSFFPLIEEVNSERQRLNLKLREKTTNKNLL
                     QLSDLEIGLVYLVTGTKQNVVLLEQIKALAIYRKLSEKEKEELDDALIEARQAVEMTN
                     LASQILDQLSGTYNNLLNNNLNDTMKFLTVWSLILTVPTIVTGFFGMNLQLPFTHSVF
                     GWGIALIISLVLSIWMLIALWRRIR"
     gene            complement(31759..32391)
                     /locus_tag="ACG8LA_000683"
     CDS             complement(31759..32391)
                     /locus_tag="ACG8LA_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HFQ0203009.1"
                     /translation="MKKIEPIPPSLPLLTKGEFYLEDEEIFSGLLINGGDQSYLDAKN
                     MVLRESHIQKLTMQKTVLRHFECSNVIFEKCDFSNLEWIGGSFHQVVFHQCKLTGTNF
                     AESYLRDCTFTDCIASMASFSSTNLKAVSFDHCQLEDSEFYEVTWKNLFLSDNQLTGS
                     NWFRTSLKGLDFTTNFFTAIALSQDSLAGLIVNQEQALVIAQALGLQIKD"
     misc_feature    32542..32667
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            32711..33235
                     /gene="infC"
                     /locus_tag="ACG8LA_000684"
     CDS             32711..33235
                     /gene="infC"
                     /locus_tag="ACG8LA_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HFQ0203010.1"
                     /translation="MTIAKDMMVNDGIRARELRLIGSDGEQLGVKTKAEALNIAEQAN
                     LDLVLVAPGAKPPVARIMDYGKYRFEQQKKDREARKKQKVINVKEVRLSPTIDLNDFN
                     TKLRNARKFLEKGDKVKASIRFKGRAITHKEIGQKVLNRLAEETADIATVEQKAKMDG
                     RSMFLTLAPKNDSK"
     gene            33307..33507
                     /gene="rpmI"
                     /locus_tag="ACG8LA_000685"
     CDS             33307..33507
                     /gene="rpmI"
                     /locus_tag="ACG8LA_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HFQ0203011.1"
                     /translation="MPKQKTHRGSAKRFKRTGKGGLKRFRAFTSHRFHGKTKKQRRQL
                     RKASMVSSGDFKRIRQQLAKMK"
     gene            33560..33919
                     /gene="rplT"
                     /locus_tag="ACG8LA_000686"
     CDS             33560..33919
                     /gene="rplT"
                     /locus_tag="ACG8LA_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HFQ0203012.1"
                     /translation="MARVKGGTVTRKRRKRVLKLAKGYYGSKHTLFKTAKEQVMNSYN
                     YAYRDRRQKKRDFRKLWIARINAAARMNGLSYSKLMHGLKVAEIDINRKMLADLAVND
                     AAAFTALADQAKEALAK"
     gene            34171..35508
                     /locus_tag="ACG8LA_000687"
     CDS             34171..35508
                     /locus_tag="ACG8LA_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate transporter"
                     /protein_id="HFQ0203013.1"
                     /translation="MSDIIIGILLVISFFFMVWYCVKGYNLMVGFAIMATVWMGLALV
                     GNTFSPNPAMEGQGVIDVLTHIYTTGPAEYAKSILVNVFFGAFFGRVLVDSGIAATLI
                     RKVVELGGDKPRITMSLLCIVTAVIFMSMTGIGPVISIAVIVLPILMSLGISVPVALF
                     SFMGSIMAGIFANIVNFKQYQTIYAGFNPAAESYTYNDYFQIGMIGMIVSLVVVLTVA
                     NISMNKKKRYAMAANVPAEGGDAPMISWLAVLLPVLGVVLLDLPIILGFILAGIWALL
                     FTGKLRGGYKEICRQFAKLFTDGAVDVAPMVGFLMTLAMFNNSAAYASPYFSAIFGDW
                     IPQSPLVLAIVFAILTPLGFFRGPMNLVGSGSAILAVVLAVNPTMSPAFLFPLFAITT
                     IAPQHLDITQSWVAWGLGYTKVTSREYMKKSIPTGWIIGAILCLITFLLYGNA"
     gene            35556..37685
                     /locus_tag="ACG8LA_000688"
     CDS             35556..37685
                     /locus_tag="ACG8LA_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydantoinase/oxoprolinase family protein"
                     /protein_id="HFQ0203014.1"
                     /translation="MKRFVRMGIDVGGTHTKAVAIDNATHEIIGKSSVKTTHDDVRGV
                     AAGVVQSFQNCLRENNISPEDVVFVAHSTTQATNALIEGDVAKVGVIGMAKGGLEGFL
                     AKRQTRLNDIDLGNKKKIEIVNAFLPVKHLNVDRVSETISSLERERAEVLVSSMAFGV
                     DNGEPERVVYEAASVKSIPTTMASDITKLYGLTRRTRTAAINASILPKMLDTATSTED
                     SVREAGVNVSLMIMRGDGGVMEINEMKKRPVLTMLSGPAASVMGSLMYLRASNGVYFE
                     VGGTTTNIGVIKNGRPAIDYSIVGGHPTYISSLDVRVLGVAGGSMVRANQSGIIDVGP
                     RSAHIAGLDYAVFTETEKIKGPKVEFFSPKEGDPADYVKVVMEDGEEVTITNTCAANV
                     LGLVQEEHFSYGNVPSARKAIQALADYCHTTVEDIAEQIMEKSYAKIEPVILELADKY
                     HLEKDQISLVGVGGGAASLITYFSNKMGVKYSIPENAEVISSIGVALAMVRDVVERII
                     PSPSKEDIRSLKNEAMNKAIESGATPESIEVHVEIDPQTSKVTAIATGSTEVKATDLT
                     KEITTEEALELAAEDMRLNKNEVCLLENTPFFYVCGEQNRSKNAGSLRIIDQKGFIKV
                     QRGHASCMKTTAANYMTAVEQLWEDMAVYQTELIARPEFYLCLGARVSDFTATDLEQL
                     QLLMDLEVSTMEPEEEVIVVAGNIKQT"
     gene            37660..38349
                     /locus_tag="ACG8LA_000689"
     CDS             37660..38349
                     /locus_tag="ACG8LA_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0203015.1"
                     /translation="MPEISNKHKLEELLNELQQIPEEIWGFYQFRRDLFWKKIPLSKQ
                     KILIQQSIDCGIETACSIKKKYPFADVGEICEQMAVPIVSCESEQINERITFATYAED
                     EGIRLMTEPLEKLKCSGLASISKETAQALIIGHELFHHIEASVKGIYTQSEKIVLWRL
                     PFYTHQSNIRALSEIAAMSFSKEMNQSDFSPYVLEAVLLWPYNEIRSQGILEEIKKIE
                     KRCTEYDLDYK"
     gene            complement(38757..39370)
                     /locus_tag="ACG8LA_000690"
                     /pseudo
     CDS             complement(38757..39370)
                     /locus_tag="ACG8LA_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374310.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
     gene            complement(39506..39700)
                     /locus_tag="ACG8LA_000691"
     CDS             complement(39506..39700)
                     /locus_tag="ACG8LA_000691"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0203016.1"
                     /translation="MKRKKQVIPMYVVKVMHGYIDKTGCRTREKNLDNLLIFKDKKES
                     EAFAKRIGGRVKPIQEVRPD"
     gene            complement(39750..40190)
                     /locus_tag="ACG8LA_000692"
     CDS             complement(39750..40190)
                     /locus_tag="ACG8LA_000692"
                     /EC_number="3.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase"
                     /protein_id="HFQ0203017.1"
                     /translation="MEKFTGYVREPFYYETDQMGIIHHSNYIRWFEEARVALLVHLGF
                     PYKKIEESGIIIPVLEVNCSYKEMIHYGEKVSIHPTIQKYTGTRLDFSYEIVGTEDKK
                     LKTTGSSKHCFLLSDSQRLVKLSKVNPELDQLFQAYASLDDVNS"
     gene            complement(40194..41039)
                     /locus_tag="ACG8LA_000693"
     CDS             complement(40194..41039)
                     /locus_tag="ACG8LA_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016836 - hydro-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HFQ0203018.1"
                     /translation="MLINEQLVKRVITPRPKISHKGTFGRIVLIGGNEQYGGAIIMSA
                     LAAVHSGAGLTTVVTDEKNRSALHSHLPEAMIVVWTDTDQFLSVIKQADVLLIGPGLG
                     TSSKSLERFKQVLENQSKEQWLVIDGSALSLLAANHLLLPYPEQTVLTPHQMEWQRLS
                     SLPIQEQRDKENKKKQQEIGAVLVLKSHETKIYGHQHFYTNPLGSAAMATGGMGDTLA
                     GMITGFLAQFPQNDQTIAAAIYLHSFIGDQLAKEQYIVLPTQISEALPKWMNYFCKKS
                     MENEA"
     gene            41188..42606
                     /gene="pepV"
                     /locus_tag="ACG8LA_000694"
     CDS             41188..42606
                     /gene="pepV"
                     /locus_tag="ACG8LA_000694"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004151 - dihydroorotase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HFQ0203019.1"
                     /translation="MTIDWQKEVEARKEDLLEDLKNLLRVNSERDDSKVTPDAPFGPG
                     PRDALKHMLAYGERDGFKVKNVDNYAGHIDLGEGDETLGIFGHMDVVPAGDGWDTDPY
                     EPVIKDGKIFARGSSDDKGPSMAAYYAMKIIKELDLKLSKKVRFVVGSDEESGWGDMA
                     YYFEHEEEPDFGFSPDAEFPIINGEKGNVSLALRFKGDNAGDYVLKSFVSGLRENMVP
                     GTATAALQVPSADAAIAMEEAFYQFIEANPVSGTIEADNTYVKIELVGKGAHGASPQS
                     GINAGSFLALFLDNYEFLGSAKQFIHVAAAYVHEDFYGEKLGVAYEDEKMGKLTMNAG
                     LFAFEENGTEEANFINMNFRFPKGVTVDGLQSDIEQTVGQEGATVTRGARVMEPHYVP
                     MDDPLVATLLQVYEDHTGEKGYEQIIGGGTYGRLLKRGVAYGAMFPGYTDTMHQANEF
                     MSLDDLFRATAIYADAIYRLAK"
     gene            complement(42663..43610)
                     /locus_tag="ACG8LA_000695"
     CDS             complement(42663..43610)
                     /locus_tag="ACG8LA_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFQ0203020.1"
                     /translation="MEQQEKIAVLIPCYNEEATISTVIADFKRELPEADIYVYDNNST
                     DRTYELAVQGGAIVKKEPRQGKGNVIRQMFFDIDADYYLMVDGDDTYPAEAVHGLLEK
                     LRSGEADMVIGDRLSNGTYFDENKRPFHDFGNNLVRNTITRMYKTKILDVMTGYRGFN
                     RIFVKSFPIMSSGFQIETELTIHALDKKFKFVEIPIDYRDRPEGSESKLNTFSDGFKV
                     IMMIIKMFKDYKPLLFFGIWTIFFFLFGLVTGIPVIREYMLTSFITRIPSAILSTGLM
                     TLALLSLVTGLILDTVVTNAKKEYELNLYHVYHEYHSRK"
     gene            complement(43833..44183)
                     /locus_tag="ACG8LA_000696"
     CDS             complement(43833..44183)
                     /locus_tag="ACG8LA_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HFQ0203021.1"
                     /translation="MYEESELSYFKGGLAVGIGLGLLSGVASTIWYHRKKVLSADQVL
                     ENIKSSFLKEGAIEGSWISFEKEPIRKFAVRSSAYRGGLSRIEDGETVYYEFLADAHT
                     GTVLEISRKKGATD"
     gene            44383..45462
                     /gene="pepA"
                     /locus_tag="ACG8LA_000697"
     CDS             44383..45462
                     /gene="pepA"
                     /locus_tag="ACG8LA_000697"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HFQ0203022.1"
                     /translation="MEEKTFQRIKELTELQGTSGFEQDVRAYMESHMEPLVDELQLDG
                     LGGIFGLRHHEEADAPRVMVAAHMDEVGFMLTQIQENGLFKVVPLGGWNPYVVSAQRF
                     TLKTSTGKNYPCISSSVPPHLLRGTSGQKSVEVTDILFDAGFESREEAMSYGVLPGDT
                     IVPYAETIKTANGKNIISKSWDNRYGCTMVLEALEALQNETLGHTLIAGANVQEEVGL
                     RGSKASVNKFKPDLFFAVDCSAADDTVTKNGTFGHLGEGTLMRIQDPGLIMLPRLREY
                     LLDIAETNNIPYQYFVSKGGTDAGAAHTQNEGIPSTVIGVVGRYIHTHQTMFSIRDFE
                     AAREMLIQTLKGLDKSTVNTIVYGK"
     gene            45606..45926
                     /locus_tag="ACG8LA_000698"
     CDS             45606..45926
                     /locus_tag="ACG8LA_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HFQ0203023.1"
                     /translation="MIIPNSLEELAGYVETGKSVFFFTAGWCGDCRFIKPQMPEIEND
                     FSDWQFIEVDRDKYIDVAAEWNIFGIPSFVVIQDGKELGRLVNKDRKTKQEIESFLES
                     VTKG"
     gene            45948..46412
                     /locus_tag="ACG8LA_000699"
     CDS             45948..46412
                     /locus_tag="ACG8LA_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HFQ0203024.1"
                     /translation="MNQEYKNILVGIDGSEQALAAFKKAVEVARRNNGKVYVANVIDQ
                     QFYNFMGYAPIDQNLVDQQTETAKEMIEECKEYGKSVDYTNIEGIIAYGSVRESMAVK
                     LPKKYEIDLIMVGQSGLNAVERFMTGSVASYVIRHSPCDVLIVSDEEEQPSN"
     gene            46617..47222
                     /gene="ytpR"
                     /locus_tag="ACG8LA_000700"
     CDS             46617..47222
                     /gene="ytpR"
                     /locus_tag="ACG8LA_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtpR family tRNA-binding protein"
                     /protein_id="HFQ0203025.1"
                     /translation="MIFAYNKAHVGDTLMVIIADDKGTENTVERKWNVARIKDEQGQV
                     VAWNFFHISDHLTIEGNGQVSLTDEELAKLNRLIKEAGFEEQLEADHEPKIVVGYVKT
                     CVPHPDSDHLSITETEVDNGTVLQIVCGAPNIEAGQKVVVAKPGAMMPDGMMIWPGTL
                     RGVDSYGMICSARELHLPNAPAKKGILVLPEDAVVGEAFPK"
     gene            complement(47261..48550)
                     /locus_tag="ACG8LA_000701"
     CDS             complement(47261..48550)
                     /locus_tag="ACG8LA_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HFQ0203026.1"
                     /translation="MDRKNVTPKMKKSKNNSLWRKLGLGLVGGIVGGLLTAGIFYAAM
                     GTGNNSSTATSGNQNSAGETVVENVKVNVDSDITKAVDKVQDAVVSVINLQSQNQSSG
                     FGGLFGQQEESSSSDDSNLEAYSEGSGVIYKKDGNTAYVVTNNHVVDGQQGLEVLMKD
                     GTKVKAELVGTDAYSDLAVLKINSDKVETVASFGDSSALKVGEPAIAIGSPLGSEYAN
                     SVTSGIISSLNRQVTSTNESNETVNINAIQTDAAINPGNSGGPLVNIEGQVIGINSSK
                     IASTSESTSNVSVEGMGFAIPSNDVVNIINQLEKDGKVTRPALGITMVDLSAVSTQQQ
                     EQILKIPSSVTNGVIVTNVQTATPAEKAGLKQYDVITKIDDKEVSSGVELQSALYKKK
                     VGDSVKITYYEGSKEKTTTVELTIDQSALKQNQNSEN"
     gene            48978..49457
                     /gene="rlmH"
                     /locus_tag="ACG8LA_000702"
     CDS             48978..49457
                     /gene="rlmH"
                     /locus_tag="ACG8LA_000702"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HFQ0203027.1"
                     /translation="MNIKIISVGKLKEKYLIQGINEYVKRLNAYAKIELIEVPDEKAP
                     ENLSEAQMRQVKEKEGERILAKIKEQEYVYALAIEGKNPTSESFAKQIDQLGIQGKSH
                     LVFVIGGSLGLSEAVMKRSNAQISFGKMTYPHQLMRLILVEQIYRAFRINAGAPYHK"
     gene            49542..50051
                     /locus_tag="ACG8LA_000703"
     CDS             49542..50051
                     /locus_tag="ACG8LA_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1456 family protein"
                     /protein_id="HFQ0203028.1"
                     /translation="MNNNDRLLRLRYAIDLKDTDLIKAFELGGVPLTKEEAQAVLTKV
                     QDKNKDNAENNVYEKTINNQVFDAFLNGLILLARGPQKDKPIVDTPQKSKEIKYINNV
                     LLKKLKIALSMTTDDILDVFAEAEIYPSKGEIGAFLRKEGQRNFKPCGDKYMRNFLKG
                     LGIYNRRKV"
     gene            50151..50801
                     /locus_tag="ACG8LA_000704"
     CDS             50151..50801
                     /locus_tag="ACG8LA_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0203029.1"
                     /translation="MNDEYKNDEDKMLFEEIENRCRLNFELRGKMSLIQQKKYLANKS
                     EFTLGHVEKLISDWISSRSEFTKIKQPIKFDMKKLLLNKSEIGNRDQYIRAKGQEIID
                     SLGEMRSYNYLYVTHRADGMVITVGKSSSNDIFLDGDLFYQLNTNHLSGTENIILRTE
                     YGNEIFAKYDEILKNYLDWAWIIPVESGDAKKLERLLGDELINKKVPILNYYSHRQ"
     gene            51252..52190
                     /locus_tag="ACG8LA_000705"
     CDS             51252..52190
                     /locus_tag="ACG8LA_000705"
                     /EC_number="1.1.1.169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015081805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008677 - 2-dehydropantoate 2-reductase
                     activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0015940 - pantothenate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HFQ0203030.1"
                     /translation="MKIAIAGAGAMGSRFGLMLHQSGNEVLLIDGWAEHVQQIKEHGL
                     QANFNGKEVEAKLPIVLQSEVEKEDQVDLIILFTKAMQLEKMLQDIQSLIKKDTEVLC
                     LLNGIGHEDIIEKFVPMENIYIGNTMWTAGLEGPGQVKLFGSGSVELQNLGDGKEAAA
                     KKLADKLSESGLNAHFSDNIHYSIYRKACVNGTMNGLCTILDVNMAELGKTSTAHKMV
                     ATIVNEFAKVAAVEKIELDVPEVIAHCESCFDPETIGLHYPSMYQDLIKNHRLTEIDY
                     INGAISRKGKKYGVATPYCDFLTELVHAKEDSLNVK"
     gene            52203..53255
                     /locus_tag="ACG8LA_000706"
     CDS             52203..53255
                     /locus_tag="ACG8LA_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HFQ0203031.1"
                     /translation="METSQKISPKIFLNKVLAGTATGIIIGLIPNAVLGAILKYFSAY
                     PFAVTIAQLAVIFQLATPLIIGGLIALQFGFDPMRMMVVAGASFVGSGVVKFTPDLGE
                     TGVYVGAGTGDIINTMLTASIAVGLILLIGNSFGSVSIVLTPIVVGVGAGLLGFYLFP
                     FVTAITSAIGSLINNFTTLQPLLMSILIGCSFAFLIISPISTVAIGMAIQLDGVSAGA
                     AAMGVAATTFVLVVNSWKVNKSGVTIAIALGAMKMMMPNLFRKPVILIPCLVSAVITA
                     IPVALFSISGTPASAGFGVVGLVGPLASLDAGLNGFLVVLCWLVIPVFAALITQFLCE
                     KVFKLYDREEVFKFLG"
     gene            53521..54156
                     /locus_tag="ACG8LA_000707"
     CDS             53521..54156
                     /locus_tag="ACG8LA_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HFQ0203032.1"
                     /translation="MIFLQKYGFYFLLLGVISDLSTPYILGLFYPKLNQMTTVISVFG
                     DVDSPVRRAFLVWSVVSGLFFVLSLPALYHLFIGTSKTLAILAVATVGLYGIGDCIFT
                     GLFSINTNESSWNLSTWIHNIGSGLGYAGFLLFPLLLVLLYRQSGQGTLSHFYLVLTV
                     ISLLIAGLYGLARIPSISQFAFFKQLGFFQRLSFFFNYLPMICLSFFQLRK"
     gene            54347..55138
                     /gene="msrA"
                     /locus_tag="ACG8LA_000708"
     CDS             54347..55138
                     /gene="msrA"
                     /locus_tag="ACG8LA_000708"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008113 - peptide-methionine (S)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_function: GO:0033744 -
                     L-methionine:thioredoxin-disulfide S-oxidoreductase
                     activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HFQ0203033.1"
                     /translation="MLDVEQMEIDLYNIILNRNTREWERTQFEEAKEDLAKMSIKQVI
                     EKLEVNLRPLALRDNLTPDAMDFYLRITGESASAKAYDYAKHKITSPLYQERAIFAGG
                     CFWCMVEPFETKPGVISVLSGYTGGETKKPNYDQVSGGYTGHVEAVEIIFDTRQITYE
                     ELLEIYWQISDPTDAFGQFQDRGKQYRSILFVVNEKQRQLAEKSREQLIQSNRFSRPI
                     VTEIRQAKTFWPAENHHQQFYQKQPKRYKKIKHSHQLHLFFQRHR"
BASE COUNT        17619 a         9922 c        11894 g        16067 t
ORIGIN      
        1 aaaaagccga gctctcgata agctcggctt tcttgtacct cggaaggatt caaataaaca
       61 gaaatgattg taactttcca tcatacatgc aaagcacggt gttgaatttc ttcatgttaa
      121 acaaaaattt tgttttcgtt acatcttcaa catttgaaac atctcttgtt cctattcaat
      181 tttcagacgt ttacgttatt caattgttac gtatcgcatt acttcttgtt tcggatactt
      241 cgtgatccaa acatccatac gcattcacta tttataggtt tgtactctac acgcatgtct
      301 gggtgaaacc tgtacttcta acaactttgt ttgcttacac tgttctatcg agaaattctt
      361 ctgtctattt gatggtatcc tccttcctta catctatata atagcatcct ttggtagcgt
      421 ttgcaaatat aagcacttta aattttacgc tttcttaaca aataatcgat aagcccttta
      481 tttgaagtaa ataaaaaaag gatgttatag taaaataagt accttttttt gtacgaagat
      541 tttaaaggag gaataggatg gaagaataca agcagacaat agaagaagta aagaaggtaa
      601 cagaagcaga tccagatact gggttgtctt cacaagaagt ggatgaacgg cgaaaaaagc
      661 agggattgaa taaattcgat gaggcgccga aagaatcgat gatcaaaaaa ttctttcgaa
      721 gcttgtccga ttttacaacg atcatccttc ttgtagcagc ggtgatttcc ttttataccg
      781 catttgctac agaacatggg gatttatttg aaggactgct gatcatcgct atcgttgtga
      841 tcaactcggt attggcgatt gtccaagaag gaaacgcaga aaaagcactg gaatccttgc
      901 aagatatgaa taaacaaacg gcaactgtca tacgagacgg caaagtgacc actgttgagt
      961 cagagcaact ggtagtgggt gatattcttg ttttagagtc cggtgatgct atttctgccg
     1021 atgcccgttt gatcgaagca tcacaattac gtgtagaaga atcggcgttg actggagaaa
     1081 gtgaagcagt tgaaaaagat gcagcattta ttgctgaaga agatgagtca ttaggtgacc
     1141 aacttaatat ggtatttaaa ggatgtacgg ttgctgcagg tcgtgggaaa gcgatcgtca
     1201 ctgccattgg catggctaca gaaatgggta agatcgcgga tcttttgaac gaaaatacta
     1261 tgcaaaaaac acctttacag gtccgattga atcagctagg caaacgaatc agtatgatcg
     1321 ctttagcggc tgcggcttta gtatttgtga ttggtgaact gcaaggagaa ccactccttg
     1381 agatgttcat gacttcgatt tccttggctg ttgcagctgt accggaaacc ttgactgtta
     1441 ttgttacgtt gacacttgca tacggtgtgc agaagatggc gaggaaacat gcgatcatcc
     1501 gacagttgcc agcagttgaa acgctaggaa ccgctaatgt tatctgctca gacaaaacag
     1561 gaacgctgac acaaaatgaa atgcgcgtcc gccgggtatg gagcaaagaa gatgaagtaa
     1621 cgaatatcga agattcaatg acgaacagcg cgatggaaat attgaaaatg gctgcactat
     1681 gtacagatgt gacggtcgag caagaagatg acgaccttgt tatcaaaggt aatccaacag
     1741 aagtagccat cgtaagggct gttgaagaga attatcatac aaaggcagaa ttagaagaaa
     1801 aatatccacg agtaaacgag cttccttttg attctgaacg aaaaatgatg acaacagttc
     1861 accaaatggg cgaaaaatac atctcaatca ccaaaggagc attcgatgtt cttgctccgc
     1921 gctttagttc aggcgatgta gaacaagcgg cgatcgttaa tgatcgcttt ggtaaacggg
     1981 cactgagagt gattgctgtt ggttatgcta cttatgacga agaaccgcaa gatatttctt
     2041 ctgaagcact ggaaaaagac ttacgtttga ttggtctgat cggaatgatc gatccaccac
     2101 gtccagaaag taaaggagca atcaagcgag cgaaaaaggc tggcatcaaa acagtcatga
     2161 tcactggaga tcatgtggtg actgccagtg ccatagcgaa agaattaggt atcttgaatg
     2221 atccgtcaga agcactttca ggatcagaac tgcatcaatt atcagacgaa gaattagatg
     2281 cgcgtgtcaa agctctctct gtctatgctc gggtaacgcc agaagacaag atccggatcg
     2341 tcaaatcttg gcaacgtacg ggtgcagtcg tagcgatgac tggggatggt gtgaatgatg
     2401 caccagcgtt gaaagcaagt aacgttgggt gtgccatggg gatcacagga acagatgtgg
     2461 cgcaaagtgc cgcagatatg attttgacgg atgacaactt tgcgacgatc gtagacgctg
     2521 tcagtcaagg acgttcggtt tatcagaata ttcgtaaagc tatcaacttt ttgctaagct
     2581 gtaatatttc ggagatcttt attgttttga ttgcgatgct gttaggatgg ggagcaccat
     2641 ttacagctgt gcaactactg tttgtcaatg tagttgctga tggacttcca ggatttgctt
     2701 taggaagaga gccagcggaa cacggcatca tggatcagcc acccattccg aaaaatgaag
     2761 ggatctttgc tcgaggttta ttgcaaaaaa ttgccataaa tgcaggggtc ttcaccatcg
     2821 taaccttgtt tggttattat ttaggtagtt atgtcgatac tatcagccca tgggtagacg
     2881 caagtcagca tgtcggtcaa actgttgcat tcttgatctt agcttattca tcgattctgc
     2941 atgtgttcaa tgtacgcagc agccaatcga tcttcaaagt caatttagcg accaataaag
     3001 ctttggtaga aatggcgtta ctggcattag ctattacaac ggctgttgct ttgctgccat
     3061 ttacgcaaga actattcggc ctagtacaca tcagtttgaa tcactggttc ttggtaggga
     3121 ttttatctat cgtaccaatc gcggtgaatg aactgatcaa gttccatcga ttaccggaag
     3181 cagaagaaga ggaatgatta actgtttcta agttgatttt ctttttactg gaactataca
     3241 aaaaggaggt gtgacatgaa tgttgtcaca cctccttttt gctaatgggc tgaatgtttc
     3301 ttttactgcc tctcgataaa cggtgttctc ctgccacccc ctcggtcaca agtcacactc
     3361 tcttttaaat atcttttggc aattgttcat aaaatgctgc ttttgttgca gaaatgtatg
     3421 ggctgagcca tagataacca ataccagcag ttgctaatgc taagatatgc cagccgataa
     3481 atgaaagatc taaccagaaa agttgtcctt tataaccatc catcaatttt cgacttgcag
     3541 tgatcgtatc cagtacttta ggtgtttgtc ctgtttcttg gacgatatcg tagtaaataa
     3601 aatagctttg agaataagaa tagcttttaa tgattccagg aataactaat agcaaacccc
     3661 ataatgttgt aaagatcgag atcagcacag ctaagctgat cactccgccg ataaacaaac
     3721 ctttgaatcc acgaaatgca tctttgaatg gttcgatctg atctttttgt ccacgtaaaa
     3781 tatcaagata agtccaagaa ataccgctca tgaacaaagc gctaatgatg ctggaaataa
     3841 ttccgccacc gcctcctgaa ctaccgcctc ctgaagttgt cgcttctgag acgctcgctg
     3901 atccatcata tatggtggtg gcaaacaaga taataggaat cataataaga agaatagtag
     3961 caataccaat caatgtaggg attagattta gtaaaacagc ttgtccccaa cgtcctttta
     4021 gactctcttt tgcttggcgt tttaattctg cagaagattg catgattttt ccctcctttt
     4081 ctttaataac accaatatac catgtatcaa aaaatatttc tgtcataatg tttttctttt
     4141 ttttgttatt cataaaaaaa ggataaaaaa aagaatatta aataaagtag aaggaagccg
     4201 agggaacttg caaaaagcac ttgaaacgat tatgatggtg ggagttgtca agatatttta
     4261 tatagaaagt agggaaatga atgacgcaac ctgccattcg ctatcgttta atcaagaaag
     4321 aaaaacatac tggcgcgcgt ttaggggaat tgatcacgcc acacggaact ttccccacac
     4381 caatgttcat gccagtagga acattagcta cagtaaaaac aatgtcccca gaagagttga
     4441 aagaaatggg tgctggcgtt attttaagta atacatatca tttatggcta cgccctggtg
     4501 aagacttagt agaagaagct ggcggactgc ataaatttat gaactgggat caaccgattt
     4561 taacagattc aggcggcttt caagtttttt cattaagtga tatgcggaat atcgaagaag
     4621 aaggcgtgca tttcaaaaat cacttgaacg gttcgcgtat gtttttatca ccagaaaaag
     4681 caatcaacat ccaaaataaa ttgggctctg atatcatgat gagttttgac gaatgtccac
     4741 cattcgatga aagttacgac tacgtgaaaa aatcagtaga acgtacgtct cgatgggcag
     4801 aacgaggatt gaaagctcat gctaatccag accgtcaagg attatttgga atcatccaag
     4861 gagcagggtt tgaagatctt cgtcgtcaaa gcgcgaaaga tctagtcggg atggatttcc
     4921 ctggttactc aatcggcggg ttatctgtcg gggaacctaa atcagaaatg aatcgtgtat
     4981 tagaattcac tacaccgttg atccccgaaa acaaaccacg ttacttgatg ggtgtcggtg
     5041 ctgctgattc attgatcgat ggtgttatcc gtggagtaga catgtttgac tgtgtcttgc
     5101 ctactcgaat cgctcgaaat ggcacatgta tgacttctca aggccgtcta gtagtgaaaa
     5161 atgcgaaata tgcccatgat ttccgtccaa ttgatgagaa atgtgattgt tatacatgta
     5221 aaaactatac acgtgcctat atccgccatt tgatcaaatg tgatgaaaca tttgggattc
     5281 gtttgacttc ttaccacaat ttatacttct tgttgaatct aatgaaacaa gtacgtcaag
     5341 caatcatgga tgataatttg cttgaattta gagaagcctt ttttgaagaa tacgggttca
     5401 ataaagaaaa cgcaaaaagc ttctaaagga aaatctttta aaaattaagt aaaaaactag
     5461 tgttatcagc atttttctgc taaagtgttt tttgtagata cagaattagt gaggtgaaaa
     5521 aaatgggaac attaccaatg cttgtgatgt ttatcgcgct attagcaatg tggtttttta
     5581 tgtcacgttc gcaaaagaaa caacagcaag aacgtcaaaa cttgttagat agcatgaaac
     5641 caggtgattc agtcgtaacg atcggcggat tacatggagt tgtttcagaa atcgacaatg
     5701 acaaacggac agttgtttta gactgcgaag ggatcttcct tgagtacgat cgtgcagcaa
     5761 tcaaaacggt caaaccaggg actgtcgtaa caaatgatgc aacgactact gttgaaacaa
     5821 cagaagaacc agctgagaca gttgaagtaa aaactgaaac aacagaaacg ctggaagaga
     5881 cagaagagaa ggaagaaaaa taagtatcaa agcttattta aagacgaggt agggcagaaa
     5941 gatgtcctac ctcatttttt attcaaaaaa gaaagagata agagcatggg atatattgct
     6001 caatattgaa taatcgggtg tgtcatataa ataataataa ataactttat atatttttct
     6061 atacaaacac ctgtaaataa agcaatttta tatttaaaaa taactgtgaa aaaaatcaca
     6121 aaaaagtgtt tacatagaaa aataaatatt gtatgatata catgtgaatt atttaacaaa
     6181 taaccatgac ccattaggag gataatgatg gctaaagtaa tagaaaaaga aaaaacgaag
     6241 acaattgacg tacaagcaat gattgatgat ttggcagaaa aagcaaatgc agcattgaaa
     6301 gaaatggaaa gctttgatca agaaaaagta gaccatatcg tgcatgaaat ggcaatggca
     6361 gctttggatc aacatatgcc attagcgaag atggctgtag aggaaacagg ccgcggtgtt
     6421 tacgaagata aagcaatcaa aaatatgtat gcgtccgaat atatttggca taatatcaaa
     6481 catgataaaa cagttggtgt gatcaatgaa gatgtccaaa aagggttgat tgaaattgct
     6541 gaaccagtcg gtgtggtttg cggagtaact ccaacaacga atccgacttc cacaacgatt
     6601 ttcaaatcaa tgatcgcgtt gaaaacaaga aatccaatcg tttttgcttt ccatccaagt
     6661 gcccaaaaat cttctgcaga agcagcacga gtggtacgtg atgctgctat cgctgccgga
     6721 gctcctgaaa attgtatcca atggatcgaa catccttcga tcgaagcgac ttctatgcta
     6781 atgaaccatc caggtatcgc gatcgtctta gcgacaggtg gagctggaat ggtcaagtct
     6841 gcttactcta caggaaaacc agctttaggt gtaggtccag gtaacgtacc agcttatatt
     6901 gaaaaaacag caaaaattaa acgtgcagtg aacgatttga tcgtttcgaa aacatttgat
     6961 aatggaatga tttgtgcttc tgaacaagct gtgatcgtgg ataaagaaat ctatgcagca
     7021 gtaaaagcag aattccaagc acaccaagtt tatatcgtaa aaccagatga attgcaaaaa
     7081 ttagaagatg cagtgatgaa cgaaggaaaa tatgcggtca atccatcaat cgttggacat
     7141 tctgcgatgg aaatcgcaaa attggcagga atcagtgtac caaaaggaac gaaaatgctg
     7201 attgctgaat tggaaggcgt aggcccagat tatccgctat caagagaaaa actttctcca
     7261 gttcttgcca tgatcaaagc taacaacacg gaccatgcgt ttgatttgtg tgaaggtatg
     7321 ttgaatcttg gaggattagg acatacagca gttatccatt cagaaaacga agagttgcat
     7381 gtcaaattcg gtcttcgaat gaaagcttgt cgtattttag tgaatacacc atctgcagaa
     7441 ggcggcatcg gtgatatcta taacgaaatg attccgtcat tgactttggg atgcggttct
     7501 tatggtaaga actctgtttc tcgtaacgtc tctgctgtaa acttaatcaa tgtcaaaact
     7561 gtagcgaaac ggagaaataa catgcaatgg ttcaaattac cgccaaaaat cttctttgaa
     7621 aagaactctc tattgtactt agagaaaatg gaaaacgttg aacgtgtcat gatcgtttgt
     7681 gaccctggta tggtccaatt cggttactgc gatacagttc gtgaagtatt ggcacgacgt
     7741 aaaaatgatg tgaagatcga agtcttctca gatgttgaac cgaacccatc gacaaatacc
     7801 gtatacgcag gaacgaaact gatggcagac ttcaagccag atacagtaat cgctcttgga
     7861 ggcggttctg caatggacgc agctaaggga atgtggatgt tctatgaaca cccagacaca
     7921 tctttctttg gtgcaaaaca aaaattcttg gatatccgta aacggacata taagatcgac
     7981 aaaccagaaa aaacacaatt cgtatgtatc ccgacaacat cagggactgg ttctgaagta
     8041 acgccatttg cggtcatcac tgacagtgaa acacatgtga aatatccgtt agcagattat
     8101 gcattgacgc cagatgtcgc aatcgtcgat cctcaattcg tcatgtcagt tccagcatct
     8161 gtcacagcag ataccgggat ggatgtgtta acacatgcaa tcgaatccta tgtttcagtc
     8221 atggcttcag attatacacg tggattgagc ctacaagcaa tcaagttagt ctttgactat
     8281 ttagaaaaat cagtaaaaac acctgatatg gaatcacgtg aaaaaatgca caacgcttct
     8341 acaatggctg gtatggcgtt tgctaacgca ttcctaggta tttgtcactc agtcgcacat
     8401 aaaatcggcg gggaatacgg gatccctcat ggacggacaa atgcgattct tttaccgcat
     8461 attatccgct ataatgcaaa agatccacaa aaacatgcga tgttccctaa atatgactat
     8521 ttccgtgcag atacagatta cgcagatatc gcaaaattct taggtctgaa aggcgaaaca
     8581 acagaggaat tagtcgaagc tttagcaacg gctgtttatg aattaggaaa atctgtcggc
     8641 atcaacatga gtctaaaagc tcaaggagtc acacaagaaa cactagatac aaccgtagac
     8701 cgtatggctg aattagctta cgaagaccaa tgtacgacag ctaatccgaa agaaccattg
     8761 atctctgaat tgaaacagat catcattgat gcttacaacg gataagcaaa agaaagcgta
     8821 gaaaaaagat aagaaaatag atgaaaaaga acttggaaaa cgttgtttct ccaagttctt
     8881 tttttaattt ccaagtaact gaaagttact tttgttattt aacatttagg tcaattttag
     8941 acagtttttg ttcaaaaagc gatatttata gtggacggta ttactgctat attaaggata
     9001 taaaatgaaa gcgtttaaaa aggtggcgta aagatgatta ttaaagaaga gatttttgta
     9061 cctaaagaat tagtgaaaga aaaaattgac ctgctcgttg aaaacctgac aacgatcaaa
     9121 gacgataatg gtgaattttt gttggacttt gatggactga aagtagatga caaaagctgg
     9181 acagtgtgga attggccaca aggtgtcggt ctatatggta tttataaaaa ttaccagatg
     9241 acaaaaaatc ctcgcgctta tcaagtggtc aatgaatggt ttgaggatcg tatggaagaa
     9301 ggcgctccgc ccaaaaacgt caatacaatg gcaccgctat tgactatggc ttacttgtat
     9361 gaagacacga aagattcacg ctatttgcct tatttagaac aatgggcaga atgggtcatg
     9421 aatgacatgc ctcggacaaa tgaagacggg ttacagcatg ccacatatgg accggaaaat
     9481 aagaatcagt tgtgggacga tacattgatg atgacagtgc ttcctttggc aaaaatcggg
     9541 aaactgttga atcgcccaga atatttagaa gaagctcgtt accagtttat gatccatatc
     9601 aaatacttga tggataaacg aacaggattg tggtatcacg gctggacgtt tgaaggaaat
     9661 cataactatg ccgaagcatt ttgggctcgt ggaaactgct ggttgacgat tgctattcca
     9721 gagatcattg aaatcttaga attatcgaaa gaagatgcat tgcgcaaatt attgatcgaa
     9781 acacttgaag cacaagtgcg tgcattaaaa acttatcagt ctgaaagcgg tttatggcat
     9841 acgttgttgg atgatccttc ttcttacgta gaatcttctg caactgcagg atttgcttac
     9901 ggtattttga aagcggtcca taaacgttat ttaccacaag aatataaaga agtcgcttat
     9961 cgtgctatcc aaggattgct tgaacaaatc gatgaaaaag gagaagttca aaacgtttca
    10021 atcgggacag gaatggggga cagtttagat ttttatcgga atatcggaat cacagcaatg
    10081 ccttatggac agtcgttaac ggtgctttgt ttgacagaat tgctcgtctc ttattgttaa
    10141 aagaaaggaa acccatatga aaaaaacatc actgctgttt gcagcaagtt cgcttagcct
    10201 aggtctgcta ggtctaagcg gctgcggaaa taattctagt gtggcaactg tcgcagatgc
    10261 agatgtaaat gagatagtta ccttgcgctt tgcttatgca agcaacagcc agccagtaat
    10321 tgatgcaatg aatgaatttg ggcgtttagt aaaagaaaaa acagatggtt ccgtacagat
    10381 ccagtatttc ccagatggac aactgggtgg agaacgtgaa ctgatcgaat tgacacagtc
    10441 aggagcagta gatttcacaa aagtaagtgc ctcagcgttg gaaagtttct ctaaagatta
    10501 ttcgattttt tcagttcctt atctattcaa tgatgaagaa catttcttta aggtgatgga
    10561 taatgaagaa ataatggagc caatctacca atcgaccaaa aatttaggat ttaccggatt
    10621 gacctattat gattctggtc agcgcagctt ttatatggta gacggtccga tccatacgcc
    10681 ggaagatttg gagggaaaga agatccgtgt gatgcaaagc gaaaccgcta tcaaaatggt
    10741 agagctttta ggcggttcgc ccgtacctat gggaagtgat gaagtgtaca cgtctcttca
    10801 atccaatttg atcaacggat cagaaaacaa tgaatttgtc ttgtatacag ctggacatgg
    10861 tggtgtggct aaatactatt cctatgatga gcatacacgt gtgccagata tcatcatcat
    10921 gaatgatgcc atcaaagaac agctaactga tgagcaggaa aaagccattg aagaagcagc
    10981 gaaagaatca acggtttttg aaattgaagc ttttgcaaaa gcaattgaag aagaaaaagc
    11041 tttagcacaa gaagaacatg gagtccaatt caatgatgta gataatacac cgtttcgaga
    11101 ggcagttgcc ccacttcatg atatattcaa aaacgatcct acctacaaag acctttatca
    11161 aaagatccaa gagcaaggag cgtagctgtg atgaaaatga ttttaaacaa ggtattagag
    11221 atcctgggag ctgttttgct tgttgggatg gtcgctgttg ttttatggca agtattttcc
    11281 agaacggttt taggaaatcc aaatacggtc acggaagagc ttgttcgatt cggtcttgtc
    11341 tggtttgcca tgttgtcttc cgcgtatgtt gtgggacaaa aagcacattt agccgtaacg
    11401 gttttaagtg aaaaattaac tggcaaaaaa agtaaaattt tagaagttgt tgttcaaagt
    11461 ttatttctgg tatttgctgc gatgatcatg gtgtatggcg gatggaatgc tgtcacattg
    11521 acaatggggc agatctcgcc ttctttaagt attcctatgg gatatgttta tctgtcagta
    11581 cctgtatcgg gggtactcat cattatctat agcctgatca atctaatcga tacattaagc
    11641 aacaagccag caattcaaga aaaaatataa aaatggagga ataaaatggc aatagaagcc
    11701 ggattagtgt tattttttgt atttgttgtg ttgcttgtat tagggatgcc gattgctata
    11761 agtattgcat tctcatcgat gatgacttta ttgttagtta taccgtttga tgtttctgct
    11821 tttagttcag ctcaaaaaat ggtgggaagt atcaatagtt tttcgctgat cgctattccg
    11881 tttttcgttc tctcgggcat tatcatgaat aatggaggga tagctaagaa actagtggat
    11941 tttgcgatgt tgttcgtcgg gcgcgtgccg ggggctttgg ctcatacgaa tgtgttaggg
    12001 aatgctttat ttggttccat ctctagctcg gccattgccg cttctaccgc gattggcgga
    12061 gtgttgatcc ctcagcaagt ggaagaagga tatgaccgga agtttgcgac agcggtcaat
    12121 atcgcgtcag ctccgacagg tatggtcatt cctccaagta ctgcttttat catgtattca
    12181 cttgttgctg gtggtgcttc gatctctgct ttgtttatgg gaggttatct cgtaggcgct
    12241 ttgtgggcgc taggaatcat gctagtagca ttcatcgttg ctaaaaagaa taaataccct
    12301 gttgtcgaaa aaggacagat ggctcatgct ggaaaaataa taaaagaggc gattcctagc
    12361 cttctattga ttgtcatcat tatcggtggt atcttgacgg ggatatttac agcagtagaa
    12421 gcttcagcga tagctgtcat ttactccctg ttgattgcta tgttttacta taaaacggta
    12481 aaactaaaag atatacctaa tatgttgttt caatcagtag caatgtcagg gacgatcatg
    12541 ttcttattgg ctacttcttc catgatgtct ttcgccatgg cgtttaccgg tattcctcag
    12601 gcaattagtt cgttgattat gggcgtaacg gataataaat ttattattct gttattagtc
    12661 aatcttgtgt tattactggt gggtatgttt atggatgtgg cgcctgctat cttgattttt
    12721 acaccaatat ttttaccaat cgtcacaagt gtaggggttg atcctgtaca ttacgggttg
    12781 ttttcaatca tgaatctgtg tgtaggctcc atcacgccgc cagtaggtac aggactatat
    12841 gtcggtgcaa gtgtaggagg cgtaaaagca gaggcaatgc tgaaaccgct tcttcctttt
    12901 tatggggtta tcttagtcgt cttgtttttg attacttact tcccgcaaat cgtcatgtgg
    12961 ctacccaata tgctgagtta ggagaatagt tatgttgaac attacaatta gaggacatga
    13021 tctttccgaa gtccaaacga tagaagatct tgcagaaaaa acaaaagaac aagggattca
    13081 tacactgcag ctcgccttag gtctttcgtt tcctgaaaca ccttctggcg caaatgagat
    13141 caattctggg atgggaaatt atgtcaaacg agttttagaa aagcaagaag tgaccgtagg
    13201 aattttaagt tgctatatca atatgattca tccagattta acgatacgac aagagttgct
    13261 gacaaagttc gagcagtatc ttcgctatgc ttcttccttt ggtgcgtcga tggttgcttc
    13321 ggaaactgga tgtgttttgc cggaaatcca atatacggaa gaaaatttca cagatgaagc
    13381 atttgctgaa gctgtgtccg ttatccgtcg cttggtaaaa gctggagaaa aataccaaat
    13441 gatggtgggg atagaaccag gtttgaatca tccggtgtat tctttagcaa gggtagagca
    13501 gctgatccaa gcagtagatt cggactatct aggaatcatt ttagatccga ccaatttgat
    13561 cacaagtagt gattatcaag aacaagtcca attggtagaa gaagcttttg aacgttttgg
    13621 tgaaaagata tgtgcggttc atttgaaaga ttttcgtgtc gaacaggaaa aaatcgtgcc
    13681 ggtaaatttg ggagacggtg tgatcgagta cacaaaaatc aaagaaatca tcatgaagaa
    13741 tcgtccgtac ctgtatgtgg ttcttgaaga aacaaaagat gatgggattc gttatggaag
    13801 aagtcttctt gaataatgta aagaagacgt tggttaacta atatttagaa tggagggggc
    13861 ggggctagaa gatgccacgt ctcttctttt ttataagagt atataaaagc agctcttttt
    13921 gattacaaaa aacgtggtat aataaaattg tgcataagtg aacaaaagga ggtgcggcac
    13981 atgctccaaa agaaaatcag cggtgaacaa gtcaatacga tggtttctga tcagtatgaa
    14041 atctatcatg tcaaagatgt cgtcagccaa aataaaacga tctatcatca tcatgatttc
    14101 tatgagatcc atgctacatt aaagggagaa gcgacttttt atttgaacgg acgacaattt
    14161 acgatcaaag caggaagtgt gctgctcatc cattccaatg atttgcatcg tatcgtccgc
    14221 caatcttcag atgtattcga gcgtgtctat atctttgtca ccccttcttt tctagaaagt
    14281 cgttccacgc catggtctaa tctatcggct tgttttcaac caatgggaga gaagaggagt
    14341 cgtgtattgc aaatagaaca ggaagtattg aagcaaaaat tatcatttat cgaccatcct
    14401 cctgataaaa aaatttacgg tgaagacata aaatatgaac aagctctggt agaatacttg
    14461 atttttctca atcaagttgt acaaaaagaa gagagtgcgc aagaacagaa tgctgtagtt
    14521 cctaatgagc gtgtggaaca aatgttacaa tatatctcaa aaaatttatc tcatccgctt
    14581 tctttagagg aaatggaaaa gcagtttttt gtcagcaaat accatatcac acgagaattt
    14641 aaaaagtaca ctggatttac gtttcatcag tatgtaatga agaaaaagct gatctatgcc
    14701 aagcacttgt tgcgagaata ccgcagctct agtgctgtat atagtaaaag tggtttttct
    14761 tcttatccgc attttctgaa agcattcaag agagagttcg gcataacgcc taaagaattt
    14821 ttgaaacgtg atacacagaa acagttggtt cattatgaac attttgaaga tgaacaatga
    14881 gaatgatcac taaaaaataa ccgcagtagc tgctgttgtt tacatagaag cagaaactgc
    14941 ggttatttta tttttatcta tatatttcaa aatattttga aaaaatgacg tacatattat
    15001 atgaatcagc tgaatttacg aaagtctctc ggcgatagtc ctgtttttgc tttgaacagg
    15061 cggctaaagt aagcaaaatt ctcaatccct atttcttcgg aaatcattcg aaccgtaaat
    15121 tctgtatacc gaagaaggtc tttagcgtaa gaaagttttt tgctgatcaa ataatcgatt
    15181 ggtggagaac cgataaattt ggaaaaatct ttgctcagct gatatttatt caataagaat
    15241 tgttgttcta attgatcaag tgtaatcgtt tctttgaaat gttcgtctaa gtattgcttc
    15301 agtttgtaaa cgtaggcggg aatatcctct tcttcgaaat ctagctgata cttttgcaaa
    15361 atcagttcat tcagcaactc gtggatagct acagaggact ggaaatcggt acgggcattc
    15421 gtgccttgtt gcatgtggat caattctgtg atcaaatggt ggatcttgtt ttctgatgga
    15481 tcccctgttg aatggaaggt gttatggccg tcttttgtga actcctgata aaatgattgg
    15541 acgttctgac cattcaaatg gatccaatcc atttcccatg gttcttcgct gatcgtttga
    15601 taacgctgat attcttggca gtcaataaaa aataagtctc cagcttttag ctgttgctga
    15661 ttatcattat atgtaagcga acctttgcca gacaaagtaa actttatcaa gtaagaaggt
    15721 aaatgtgctc gttcagtata gtaagggatt ggtgctttga agtaaccgat ttcttggata
    15781 taaaaaaata aattcctgct tctttgtgta ggcgtcaaga tcactctttt tgagtcttcc
    15841 gaccatgagt ggttggcttt ttcccagtaa tccatgtaaa cactcccaac ttgtcaagat
    15901 aatgcaatta tataccaaaa tagtgtgaag caaaatataa gattctgtat tatgatagca
    15961 ttgttaataa atgataacgc tttattaata aagtgctaat caacaataaa gtaaaagagg
    16021 tggagaaatg aatccaacat ttgttgccat cgatatcggt gcatcaagcg gacgactaat
    16081 gaaaagtacg agggatgcaa aaggttcttt gatcttggaa gaagtacacc ggttcaaaaa
    16141 cggctttcgg aacaaagacg gtcacgatcg ctggaagatc gattatctta tcaaagagat
    16201 tttgattgga tttgaaaaat taaagcagac agggattgat cgcctttttg cggggatcga
    16261 tacatgggca gtcgattact gtctgattga tgaacaaggg gatcggataa atgatccgat
    16321 tgcttatcgg gacaagcgta ccaatggagc agtagaacag ttttctgaaa tctattctct
    16381 agataagttg tatgagcaga cagggattca gatccagcct ttcaatacct tgttccaatt
    16441 gtttgctgaa gaaaaagaaa atttggcaaa agcacataaa ttgttactga tacctgatta
    16501 tttagggtat gtctttactg gtaacatggt gacggagaaa actaatgcat ctactatgca
    16561 gctgctgaat gcagggacaa aagaatggga aatagaactt cttgaaaaaa tcggtgtctc
    16621 gaaggaatta tttccaccat tgacagagcc gggaacgata ctaggagatc tgcaaaaaga
    16681 acaattttca aaatatgatt tgccagatgt gacctttatc acagtagcaa gtcatgatac
    16741 ggcgtcagct gtattaggaa cgccaggtca aggagaacgt tggggttata tcagcagtgg
    16801 gacatggtcg cttttaggga ttgaaacaaa gatcgccaat gtttctcgca atgctttttc
    16861 tgaaaattat acgaatgaat ggggtgccca taacacggtg cgttttttga aaaacatcat
    16921 ggggatgtgg ttgatccagg aagttgcccg aatgcaagag tacgagtaca gttatgcgga
    16981 attggcagag cttgctgcaa aagaaaaacc gctgcagcaa gtgatggaaa tcaatgaccc
    17041 tcgatttttg aatcccccaa atatgataga agagattcag caatactgtt ttgaaacaga
    17101 gcagccagtc cctgtctcat cgggagctat cgctcgttgt gtgtatgata atcttgctct
    17161 ttgttacgca caagagctga tcaaagtaga acacttaact ggaacgaaat tggaaaagct
    17221 gcacatcgta gggggcggat cgaataatcg tctactgaat caattgacag cagattatgc
    17281 cggaatcatt gtagaagcag gacctagtga agccacagca atcgggaatg ttgccatgca
    17341 aatgctcagt acaggtcagt tttcgaatat agaacaagca agaaatgtaa tcaaacagtc
    17401 gtttccatgt gaaacttttt acccagatga aaataagcaa aacacgatgg aatggtacgt
    17461 gaataaaatc aaaggagtaa tcgtatgaac acgattgaaa gaaattacga acaagcaaaa
    17521 gaaaaatatg caactatcgg tgtagataca gatgctgtac tagaaaagat acaggacatc
    17581 aaaatttcta tgcattgctg gcaaggagat gatgtcaaag gtttcttgac accggatggc
    17641 gaattgaccg gtggaatcat ggcgacaggg aattttccag gagccgcacg aacacctgaa
    17701 gagcttagac aagatctgga gaaggcttat tcgttgatac cgggcaaaca caaattgaac
    17761 cttcatgcta tctatttgga tacagaagaa tctgtcgatc taaatgaaat tgagccgaaa
    17821 cattttgaaa aatgggtaga gtgggcaaaa aaagaagaaa tcggtcttga cttcaatccg
    17881 actttctttt cgcatccaat gatgaaagac ggctttacat tggctcatcc agataaagaa
    17941 gttcgtgaat actggatcga acacgggaaa agaagccgca aaatcgcgga gtactttggg
    18001 aaagaaactg ggcaaacaag tatcaataac ttttgggtac ctgatgggat gaaagataat
    18061 ccgattgatc gttttacccc acgggaacgt ttaatggaat cactcgatga aatttttaca
    18121 gaagagttag atgaacggta tgtacaagat gcagtagaaa gcaaactatt tggtttaggc
    18181 gctgaagctt atacagtcgg ttcccatgaa ttttatatgg gttacgggtt gactcgtgac
    18241 aaacttgttt gtctagatgc tggacatttt catccaacag aagtgatttc caataaatta
    18301 tcttcattag ctttattcag caaaggaatc atgttgcatg tttcccgtcc agtgcgttgg
    18361 gattcagacc atgtggtttt gatggatgat gaattgcagg aaatcgctaa agaattagtc
    18421 cgtaacgaat tgttggaaaa aacaaatatc ggtctggatt tctttgatgc aacgatcaac
    18481 cgtatcgctg cttgggtcat cggtacgaga aatacacaaa aagcactgct gaaagctatg
    18541 ctggaaccag ttgagcgatt gaaagaaatg gagctggctt ttgactttac ttcaagaatg
    18601 gcttatacgg aagaattgaa agatttcccg tatgccgatg tatggaatta tttctgttac
    18661 aaaaatcaag ttccagttgg tttggattgg ctggaagaag tccaggaata tcaaaaagac
    18721 gtgttggaat taagaaaata ggagtgtggc tatattgaaa aaaatagata ttttacaagc
    18781 gccttatgtg aaagaaatga tcgaaacgac gtcgaatctt tatcgcttgg gatgggatga
    18841 aagaaatggc gggaatattt cttatttact aaaagaagaa gagatcacac cgttcttgga
    18901 tcctgaaaaa gtgatccgcc gcatctcgat gatttttgat gccagccgtt tagcaggatg
    18961 ctattttatt gtaactggtt caggaagata ttttaaaaat gtagcgagcg aacctgccga
    19021 gaatcttgga atcgttcgag ttgctgaaga tggcaaaaca ctggaacttt tgtgggggct
    19081 ggaaaacgaa tgccttccta caagcgagtt gccaagtcat ttcatgagtc atatcgcccg
    19141 tttagaagta gacccagata atcggatcgt tatgcattgc catgctagtc atctattagc
    19201 gatgagtttt acgcatgaat tagacgaacg ttcctttagt cgtacgctat ggcaaatgtg
    19261 tacggaatgc ttagttgttt ttccagaagg aatttccatc attccgtgga tggttccggg
    19321 aacaaatgag attggggaag caacagctga aaaaatgaaa gaaactcgat tggttttatg
    19381 gccacaacat ggaatctacg ggtcaggaaa agacatggat gaagtctttg gtttgatcga
    19441 gacagcagaa aaggcagcag aagtctatac gtacgtcaaa gcgcaaggac caatcttgca
    19501 aacaatcacg gacgaaaacc tgtggcattt agcagatgcg tttggtgtca ctccaaaagc
    19561 aggttatttg gaggaagttc atacgaaagc aggtgtctga catggtgaaa aaagcttttt
    19621 gcatgaaagt ttacccagaa aaacaagaag aatacaaaaa aagacatgat gaactttggc
    19681 cagaaatgcg tacagcactt cgtgaacacg gggtcatcga ctattcgatc tatcttgatc
    19741 cgagtacaag tttgttattt ggttacttag tgatcgaaga tgaaaagtta tgggaaaaaa
    19801 tggcaaatac atctatcaat caaaaatggt ggaagtacat ggaagatatc atggagacaa
    19861 atccagatgc ctctccagtc agttgggaat tgatgccagt ctttgaactg tagcaacaag
    19921 caactgggca accggttgct tggggttctt tcgtttttat tgtgaaaaaa aatacaaatt
    19981 aggaggaata gaaaatgagt aatcgaatga ttttaaatga aacatcgtat tttggaaaag
    20041 gagcgattga gtcgatcgtc cctgaatttc agcagcgagg attcggcaaa gcagctgtca
    20101 ttactgacaa aggattgatc gagcacggta tagcaacaaa agtaacagaa cttctagata
    20161 aagcagcaat cgcttatgct ttatacgacg ggatcgtacc taatccaacg atccaaaatg
    20221 taaaagatgg agtggctttt gttaaagagg cagaggcaga ctgtttgatc gcaatcggtg
    20281 gaggttcgcc aatcgatacg gcaaaagcca ttgggattat tttgacgaat ccagagtttt
    20341 cagacgtcat tagtttagaa ggtgttgctg atacgaaaaa tccatgttta cctatattag
    20401 ctataccaac gacttctgga acagcagcag aagtaacgat caactacgtc atcacagatg
    20461 aagtaaatca ccgaaaattt gtttgtgttg atcctcatga tatcccaatc gtcgcgttca
    20521 tcgacagcga tatgatgatg ggaatgccga aaaaattggc tgcatcaaca ggtatggatg
    20581 ctatgacgca tgctattgaa gggtttatca caaaaggcgc ttgggaaatg actgatatgc
    20641 tgcatttaaa agcaatcgaa atcatcggcc attctttgga agtttctgta gatggcgatc
    20701 aaaatgggcg agaaaaaatg gcattaggac agtatattgc gggaatgggc ttctcaaatg
    20761 tcggtttagg actggtacac gggatggctc acccgttaag tgcatggtac aacattcctc
    20821 atggcgtagc gtgtgcagca cttttgccaa ctgtcatgaa atataacaaa gaatatactg
    20881 gagaaaagta ccgtgagatc gctcttgttc tagggattaa aggagcagct gaaatgtctt
    20941 tagaagatgt aagagaagcg gcttgtggtg agatcgatcg gttgagcaaa gcggttggaa
    21001 tcccagaaac catttctgaa ttaggtgtaa aagaagcaga tattccagca attgcagaag
    21061 atgctttgcg agatgtatgc acaccaggaa atccaagaga aacgacagta gaagaaatca
    21121 ttgctttata tcaaagtttg atgtaaaaac gaagcggatc ttcaacatta aattgcctgt
    21181 aaagagaaat ggtagtttat atctggatat ctcttttaaa ttgatggtat ttccgctata
    21241 atttttctta taaagaaata ggagaatatt atatggaaaa taaaaagcct tatggaactg
    21301 tattgatcaa agcctctaaa atactagact atttagcgga aaaccaagat gtctctttgc
    21361 agacgatcgc aaagggtgtg ggaatgacct cttctacagt cttgaaaata ctagatactt
    21421 tgttgatgat cggctacgta aataaaaatt cagagaaaaa ctatcgttta ggtgcaaagc
    21481 ttattcgcta cgcgaataaa aacattgaac aaatcgattt ggtagagttg actttaccgt
    21541 ttttagaaca gctgcagcaa aagatcgatg agactatcca cttaggggta ttggacaaca
    21601 atgagatctt gtacgtgaac aaactagatc caaaacatca aacgatccgc atgtcttcaa
    21661 aaatcggaat cacccgacca ttatacaatt ctgcgatggg caaagccgta ttagcagaat
    21721 tcagtgaaga gcagtacact gattatcttg aaaagcatcc gttgatccct tacacagaat
    21781 atacgatcac caatgcatta cggttgaaaa aggaaatcca aacggtaaaa gaaacccaca
    21841 tcgcatttga cgatgaagaa atcgaacgtg atattttttg tataggagcc tcaatcgtga
    21901 aaaacgaaca aatcattggt gcatttagtg taagtatgcc gaaatatcgt ttaacagatg
    21961 agacaaaaga acaaataatc agtgccctca agcaaacaaa aagcgaaatc gagcaaagaa
    22021 ttcaaaaata atgaaaaaag cgtttgcaat ttttcttttc tgccgtataa tatgggtata
    22081 gatttccaag ttataaaata aaatttctaa ataggaaata ggtggagaag atgaaaaaaa
    22141 ttgatatttt atctcgattg aaaaacgccg gagtgattgc ggtggtacgc ggaaaaagca
    22201 aagaagaagc tttgaatgct tgccacgcaa tcatcaaagg tggtctaact ggtattgagt
    22261 tgacttttac agtccctcaa gcagatcaag taatcaaaga acttttgtca ttctacaaag
    22321 accaaccaga aatagtgatt ggcgcaggca cagtattaga cgctgtcaca gctcgcttgg
    22381 ctatcttagc tggcgcagag tatattgtta gcccttcctt tgatcaagaa acggcagaga
    22441 tgtgcaatct gtatcaaatt ccttacttac caggatgtat gactattacc gagatcaaaa
    22501 cagcgctgaa aagcggggta gatatcgtca aactatttcc tggaagcgct tatggaccaa
    22561 gtatcatttc tgccttcaag gcgccgatgc ctcaagtcaa tatcatgcca actggcggtg
    22621 tgagtctgga caatatgaaa gagtggttcg atgctggtgt cgtaacagtc ggagtaggtg
    22681 ggaacctttt agcacccgca gctacaggag attttgacaa agtaacggaa gtcgcgcaac
    22741 agtatgcagc aaaaatgaaa gaaatcaaga ggtagctgct tatgggaaaa gtagtgacac
    22801 tcggagaaat catgttgcga ttgtccacag agcagggaac ccgtatcgat tcaagtgaac
    22861 gattcgctgc ccattatggc ggaggggaag caaacgtagc aatttcttta gctaattacg
    22921 gacatgaagc gatttttgct acaaaagtac ctgataacgc attgggaaaa gcagtcaaaa
    22981 agcacttgca atgttatgga gtagatacga aacaggtatt atctggtgga tcaagactag
    23041 gtacttatta tatggaaact ggtagtggcg aacgcgccgc ctcagtgatc tatgatcgtg
    23101 ccggatcaag ttttgctgaa atggatcatt tggaatggtc gctagaggag ttattccaag
    23161 gaatagatat atttcatgtt tcaggaatca ccccagcttt gtctaaaaaa tggcaaaaaa
    23221 tgacgaaaca ggtgatagaa gctgcaaaaa aagctggctg cctgatcagc ttcgatatca
    23281 actatcgtgg aaaattatgg acacagcaag aagccagcga agtaatccat cagcttttac
    23341 ctttagtaga tatctgctca gctggaaaaa tggatgctct ttatttgtta ggtatcgaga
    23401 aagcgccaga agcagaagaa caacctctaa tttattatta tcaaaaaatg caggaaaagt
    23461 tcccgaatat tcaggtgttt tattcgacca agcgtaccgt tcattcagca agtgaaaatg
    23521 aattgaaggg gacattgtgg atgaaccatg aatatgtgga atcccaagtc catagaatca
    23581 ccccaatcgt ggatcgagta ggtggcggag atgcttttgc aggtggcgtg ctccatggga
    23641 ttttatccaa tatgtctccg caagaaatca ttgattttgc tacggcagct tctgccttga
    23701 agcatacgat ccatggggac tgcaaccaat ttagtcaaga agaagtcgca caatttttag
    23761 catgcggctc tggaaaaatc attcgataga aggagtagaa gaaaatgcaa gaaatggaaa
    23821 cacgttatac acacagtcca gaagatatcc gtcattattc aacggaacaa ttgagaaaag
    23881 aatttttagt agaaaaggta tttgaaccag ggaaaatcag tttgacttat acgcacaacg
    23941 atcgaatgat ctttggtgga gtgacaccta ctgaaaaaga attagaaatc acattagaca
    24001 aagaactagg tgttgattac ttcttagagc gtcgtgaact aggtgtgatc aatatcggtg
    24061 gaccaggatt catcgagatc gatgggcaaa aagaagaaat gaaaaaacaa gacggatact
    24121 atatcggaaa agaaacacga catgttgtat tttcttctca agatgctgaa aacccagcta
    24181 aattctatat tagttctgtt ccagctcatc ataaatatcc aaatgtaaaa atcagtatcg
    24241 accaagtaaa accaatggag actggtgaag gcctgacact gaatgaacgt aaaatctacc
    24301 aatacatcca tccaaatgta tgcgaaagct gtcaattaca aatgggttat acgattttag
    24361 aaccaggaag cgcttggaat acgatgcctt gtcatacaca tgaacgtcgt atggaagctt
    24421 atgtctactt tgattatgcc aatgaagata cacgtgtgtt ccacatgatg ggcaaaccag
    24481 atgaaacaaa acatttagtt gtagacaatg aacaagccat tatttcgcca agctggtcga
    24541 tccattcagg tgtaggtaca agcaattact cattcatctg ggcaatgtgc ggagaaaata
    24601 tcacctatac agacatggat atggtgcaaa tggatcaatt aaaataagca taagggagag
    24661 aaaatgatgg aatttagtat ggatatgttt cgtttagatg gaaaagtagc attagtcacc
    24721 ggtgctgtct atggtattgg atttgagatt gcacgctctt tagctacagc aggagcaaaa
    24781 atcgtattta ataacttgaa tcaagaatca gttgatgaag gtatagcgca ttataaagaa
    24841 gcaggcatcg atgcaaaagg ttatgtctgc gatgtgaccg atgaagaagc ggttcaagcg
    24901 atggttcaac agatcaaaga agatgtaggt tcagttgata ttctagtcaa caatgcaggg
    24961 atcatcaaac ggacaccgat gatcgaaatg gatgcggcag acttccgcca agtaatcgac
    25021 gtggatttaa atgccccatt catcgtttca aaagcagtta ttccggatat gatcgaaaaa
    25081 ggcggcggta aaatcatcaa tatctgctcc atgatgagtg aattaggacg cgaaacggtc
    25141 agtgcttatg ctgcggcaaa aggcggatta aaaatgctga cgaaaaacat cgcttctgaa
    25201 tacggtcaat acaatatcca atgtaatgga attggaccag gttatattgc tacaccgcaa
    25261 actgctccat tacgcgaaac acaagaaaac ggtgaacgtc atccattcga tcaatttatc
    25321 gttggacgta cgccagcagc acgctggggc gagccaatcg atttggctgg accatctgtc
    25381 ttcttggctt ctagcgcatc tgatttcgtt aacggccatg tcttgtatgt ggacggaggc
    25441 atacttgcct atatcggaaa acaaccttaa aagagcttta gtacactgtt tagtggagag
    25501 gttgtgaaat cagcggattg aacgaatacc gaaggacagc tgattaaaca tcatttattc
    25561 gaaaaaagag gctgggacag aagcatttaa ctccaagaaa taagaaggaa ttcacgaaaa
    25621 ttgcttttca aatttttgtg aatttcagct tatttccgaa ggagttgctt ttacttccgc
    25681 cgtttgtacg tgtttagagc gtgagacaaa agtgttcttt acttttgtcc cacgctcttt
    25741 tctgtgcgtc ttccatactt cactaagtcg atccctcttg cttcgcacca atccttcact
    25801 ggtccggaaa agatcagaga ttgttggtgt agggccgcgg tattcgttgc gccgaccata
    25861 gtataaagca gacgaagctc ttcttgccat tgcttcatca gtataatagt ttcttctacg
    25921 ccgtgattca tcagatgcgt cagtacggtt cctgaagtac ccacggcatt tgcgccgaga
    25981 caaagggctt taaatatgtc ataggcattg cggatacctc cggaggctag gatttccata
    26041 gaagtgtctg cttcatttgc ttcaagcaat gaagagactg tcgattgccc ccagtcagct
    26101 aaataactca gttcccgctt ggagcgacgg gcgttttcga tctgggtgaa gcttgttccg
    26161 cttcgaccgc tgatatcaac tgtatgaact cctaaagcag ctagatcatt gagcgtttct
    26221 cttgtcatgc caaaaccgac ttcttttacg atgaggggga cgtcaatggc tgtttgagtt
    26281 tcttgaataa gtactttcca attggtaaaa tcacggtctc cctcaggcat aaccaactct
    26341 tgaggtgcat tcaaatgaat ctgtaaggca tctgcgtgaa acaatcggat agcttctttg
    26401 gctctttcga cagaagtccc tgcaccgatg ttggcaatga ttttcccgtg aggatattct
    26461 tgtcgcataa tcgtataagt atcggctaaa gaagggactt tcaaggcagc gctgactgaa
    26521 ccagtggcaa tcatcaaatc tgcttctctt gcgacgattg caagatcttg gttgattttt
    26581 tttgtttttt cgcttccgcc agtcatcgca ttgatataaa atgggctgct tagtgtaaac
    26641 ccaactgcct gtgtacttag atcgacatca gaaactgcta tttgcggcaa agggttatgg
    26701 atgatccgta cgaagtcaaa ttcgtttttt tgtttatcat gaaaggcttt agctagtgaa
    26761 acatgttcgt cttttcgatt catcggtttt cctttctttg atcgctatag acatgtaacg
    26821 gcagtggagt gatttctgct ttttcccatg cactcattaa aggaagaatg ccagatttct
    26881 ggtcaacaat tacgattccg caatcgcccc cacctgcacc agaagatttt gcggctcctt
    26941 catactgttc agctaaatta cacaatttgt tcaaagcagg cgtttcgatg acgaccccag
    27001 tgattgcaga taaatcatgc agtaattgtc ggttttttcg aatcatctgt tggatcaacg
    27061 ttacattatt ttctttaaac cctttgatca tttcgttgac acattctgta ctatttttta
    27121 agaaaagctg ataagccacc attttatctt ctctcgaacg gtgaacttga tcgaccaaat
    27181 cagaagtaga ggcagggcta cccgtccaac caatcaataa acgtaaatct tcaggagcaa
    27241 tcaatggctc aatggataga cctggccaat ccagggcaag taactcactg atagaatgct
    27301 gagtttcttg ttcttggagc caaggatggt cgaaggttga gaaagcgatc cagccaccat
    27361 aacagctagc agcgatgtcg ccgcaggaac cattatcttg aactgctaaa ttggctagtg
    27421 ctgcaatctt gaaaatctcc aactgagata aattcaacgc gtaaaaaaca ttcaaggctt
    27481 tgaccgttgc aacggtcacg gcaccgctag aacccaatcc atatttccgg ccatttgaac
    27541 tgtctaactc acttgttact ttcagatcat aaaaggataa aagaatgttt ttttcttgtg
    27601 catacttttc agtcaagcga atagcagcaa ggatataatg aaaaggattt tcccgaatat
    27661 ctaaaactaa ttctccgttg cgtcttgtcc aacgtacagg catcccacta tattgtgcag
    27721 attggatact tccgactttt cgtgcagatt ctacagtgac tgtcacgaat tgatcgactg
    27781 cagcgataac tgctggatgg cctgtttcaa caactgcata ttctccggca atatagagtt
    27841 tgcctggtgc agatacttca atcataaaaa tctcccttta ttcaataatc gcaattcctg
    27901 gaccagcatg tgcagtaatt acttgttctt tgctaaataa tttggtaaat gtttcttgta
    27961 cctcagataa atggctgttt tccactaaaa ctttgacatt agggccagca tccatcgtaa
    28021 agtagcatgg aatgccttgc tttctcaatt gtcgcaccgc atccatcgct tttaagctgt
    28081 caggagacca gtaagtgaat ggaggctggg cagctaaagt cgttccatgc atttttagtc
    28141 cgtttctttc catcgtttct ccgagaagtt ggaaatcttt tgttttgatt gcttgtttca
    28201 attgatatag atccccttca acggaatcta accagccttg ataaaaactg gatgtttcga
    28261 ctgtccgacg catcccattt ctgctggaca cttctttttt ctggtcgttg atcaaaacga
    28321 aaaccattgc taaatcgtct tcgaaagaat cggaagggac tggcttagcg taagaactta
    28381 agtcgtcatg gcctttttcc cattcgacga aaccaccgaa aatacttcgg caagctgaac
    28441 cagacccgcg tcgagcaaat cttgaaagag agagatcatc taatccaagc ttaagagcag
    28501 tattgcaagc gcctgctaaa gcagctagcc cgctggcaga ggaggctaat ccagctgcgg
    28561 taggaacgaa attctgactg attactgaag cttttagtga gaggccggct tctttacgaa
    28621 aaaggtcaag aaactgactg actttttttg ttgctttttc gtcttgcaag gtgccatcta
    28681 gataaaattc atctaccata tagctatcag aaaagatgac ttctgtctct gtataaaatg
    28741 catccaatgt taacgaaagg ctgttgttca ttggaaggat gagttcttca tttttcttac
    28801 cccaatattt gattagagca atgttggtat atgcgcgtgc tttgccttta aacataggta
    28861 tgtactccta atccttgtat ccaagtttca gcagcacccg catcttcaag tgcttgactg
    28921 atttcttggg cttttgtttt tgtttgtgct aatgcaatca tacagccacc gcgtccaccg
    28981 ccagttaatt tggcacccaa tgccccggta tcttttgctg tttggatcaa tagattaaga
    29041 aaatcattgc tgattgtcag cttttccaga agtgattgtg attcatccat tgtctgtgcc
    29101 aacgtttctg gtgaattttc aatgattgct tgttttgctt gcttcgtcaa gtatcctaat
    29161 ttttggatca tttgtccagt ttcatgaggc tgggtttcaa agaggtgagc gacatctttg
    29221 acggcttctc ttgtttgtcc tttgattcct gtatcagcga caatcaaaaa agcatcgatg
    29281 ttcaaagaaa agtagtcgaa aggatgccct tttgtaaaat aaatcggctg caagctgcta
    29341 gtagcggctg catcgattcc actaggatta ccgtgggcga ttttttccga aagctggaca
    29401 ttttctaata gtatttcacg agacaaagga aatgctaagt aatcataaaa agcacgagtg
    29461 actgctgtgg cgactgcagc gcttgatccc attccacgtt cagcaggaat cgtgctttca
    29521 atggtcagtt gcaagttttt ttggatgtca tgctgttttt ttaagtgaat gaataatttt
    29581 ttgatatttt ttaatgcatg aggagcttcg gctaaatttc ctgaatagta ggaagaaacc
    29641 agttgatcgt ccattgcatc cagctcttca aggaatgcgg tgacttttgt tgcatagaaa
    29701 ggaaaggcaa tcgctggttc tccataaaca accgcgtgct cgcccatcaa tatgatcttt
    29761 ccgcttgatt ctccttggcc atagtttgcc ataatctaac tccttctcac gtaaaagtga
    29821 tttttaagca aaaaataaag cgcccaaaac gagttgcgct gcttcacgaa tttttttgtc
    29881 cactaagggt ctcaaaaaac attcctcctt tattttacta aaaccatctc agaagtaaaa
    29941 ctaagaatac gttttctaaa gaaaaaacac ttttttctta agaatttttt gacttttttt
    30001 cttctttgac tagaaaaaaa tacaattgac actactagat attgggggta tatttaaaaa
    30061 ggttggagtt aaacacaata tttagtgatg aagtgagctg gaggtaaatg agcgtgatcg
    30121 ttttagcagg tacaattggt gccggaaaat caagtttaac agaaatgatg gctgaacact
    30181 ttgatagtca ggcattttat gaatcgattg atgataatga agtcttgccc ttattttatg
    30241 caaaccctga acagtatgct tttttgctgc aaatttattt tttgaataaa cgttttgcaa
    30301 gcatcaaaca agcaatgaaa gatgacaata atgtattgga ccgttcgatt tatgaagatt
    30361 cactgctttt ccatctaaat gcagatctag gaagagcaac agaaacagaa gttcgtgtgt
    30421 atgatgaact gctggaaaac atgatggaag aacttcccta tgctgcccat aaaaaacatc
    30481 cggatttatt agttcatatt cgtgtatctt ttgatacgat gttggagcgt atcgaaaaac
    30541 gtggtcgttc gtatgaacaa ttgtcctttg atccaagtct atacgattat tacaaagaat
    30601 tgaacagacg ttacgatcaa tggtatgaag aatacaaaga aagtccaaaa atccaaatcg
    30661 atggagaccg ctataatttt gtggaagatc ctcaagcaaa agaagaagtc ttgaaaatga
    30721 tcgaagaaaa attagcagag attcgccaaa ccaaagtagc catttgattt acagttgctc
    30781 aaataaaggg taaaccttta tttgagcgac ttttttcttt atactggaaa caaatgtcag
    30841 gaggatagag tatgcgggaa aaacactatt ttaatcaaga ccgtaatttt tggatcaatg
    30901 tacagcaaaa cgatgtgcta gctgttaaaa acttaaaaga agaatatggc attagtgacg
    30961 agatgctgac ttattctcta gataaaaatg aacgggcgcg cgtagagtac gattcttttg
    31021 atgaagcgtt actgcttgta tcaaatgttc cgcaccagca aaaagtcgat aatcattatg
    31081 aaactagtcc tatcgctttt attttaaaag aagacggttt gtttacattt accacgccga
    31141 ataccgagta cgtgattcga ctaattcgat cgcttttgga acgaatgcca gacatgagtg
    31201 tatacagttt attgtttcgt acattgtttt tgatttctga ttcctttttt cctttaatcg
    31261 aggaagtgaa tagtgaacgt cagcggctta atctgaaatt aagagaaaaa acaacgaaca
    31321 agaatctgct gcaactttca gatttagaga tcggtttggt ttacttagtt acaggaacaa
    31381 aacaaaatgt agtactttta gaacaaatca aggcattggc tatttatcgc aagttgtcag
    31441 aaaaggaaaa agaagagttg gacgatgcgc tgatcgaagc acgacaagca gttgaaatga
    31501 cgaacttagc ttcgcagatt ttagaccagc tctctggcac ttataataat ttgctgaata
    31561 acaacttgaa tgacacgatg aaatttttga cggtctggtc gctgatcttg accgttccaa
    31621 ctattgtgac aggattcttc ggaatgaatc tccagttacc ctttacccat tccgttttcg
    31681 gatggggaat cgccttgatc atcagtttgg tcttatctat ttggatgctt attgcactgt
    31741 ggcggcggat tcgttgatct agtctttgat ctgcaaacca agggcttggg cgatcacaag
    31801 tgcttgctct tggttgacga ttagtcccgc caaagaatct tgagataaag cgattgctgt
    31861 gaagaaatta gtcgtaaagt ctaatccctt cagagaagtt cgaaaccagt tcgaaccggt
    31921 caactgattg tcagacaaaa aaaggttttt ccaagtgacc tcataaaatt cgctgtcttc
    31981 taattgacaa tgatcgaagg agacagcttt caagtttgta ctactaaagg aagccatcga
    32041 agcaatacaa tcagtgaaag tacagtctcg aagataactt tcggcaaaat tcgtacctgt
    32101 taatttacat tgatgaaaca cgacttggtg gaaactgcca ccaatccact ccagattgga
    32161 aaaatcacat ttttcaaaaa tgacattact gcattcaaaa tgacgtaaaa ctgttttttg
    32221 catcgtaagt ttttggatat gactctctct taataccata tttttggcat cgagatagct
    32281 ttggtcaccc ccgttgatca gaagaccaga gaagatctcc tcatcttcta aataaaactc
    32341 tccctttgta agaagaggaa gagaaggtgg aataggttcg atttttttca tgtgggttca
    32401 cctcgttttt ctttagtata gcaaagaagc gggaatcact gctagaaagt ctgctaatct
    32461 aatcattttc agaaaaggaa gacaaactgt atgaaaaaca ttgacaaaaa gattagtttt
    32521 tgctatacta tgatggttga gaaataaaag cagaagcacc cgcttctcgc cttagttgat
    32581 aatgtcactg ggctagatag ttttcactgg ttctattagg tgaagtacgc gcgggttctg
    32641 taagagaact cgttttttta ttgccgttta ttcggtaagc ttttctttct ctcataatat
    32701 ttggaggtga atgaccatag caaaggatat gatggttaac gacggcattc gtgcacgaga
    32761 gttacgattg atcggttcag atggtgagca attaggagtt aagacaaaag cagaagcatt
    32821 gaatattgca gaacaagcaa acttggatct tgtgttagtt gcccctggtg cgaaaccacc
    32881 agttgcgcga atcatggact acggtaaata ccgtttcgaa caacaaaaga aagaccgcga
    32941 agcgcgtaaa aaacaaaaag tgatcaatgt aaaagaagtt cgcttaagtc ctacgatcga
    33001 cttgaatgac ttcaatacaa aacttcgtaa tgcacgtaag ttcttggaaa agggcgataa
    33061 agtgaaagct tctatccgtt tcaaaggccg tgccattacc cataaagaaa ttggtcaaaa
    33121 agtcttgaat cgcttagctg aagaaactgc ggatattgca acagtggaac aaaaagcgaa
    33181 aatggacgga cgcagcatgt tcttgacgct ggcaccgaaa aacgacagta agtaatttga
    33241 atgactaact ggctgttgga cagccgatag tcggataacg aaagattttg aggaggaaat
    33301 atagtcatgc caaaacaaaa aacacaccgc ggatcagcaa aacgtttcaa acgtactggt
    33361 aaaggcggat tgaaacgctt ccgcgcgttt acaagtcacc gtttccacgg caaaacaaaa
    33421 aaacaacgcc gtcaattgcg taaagcaagc atggtttcta gtggcgactt caaacgtatt
    33481 cgccaacaac tagcaaaaat gaaataagaa gtacaaataa cagaatctga agatttattt
    33541 ttattaggag gaattataca tggcacgtgt taaaggtgga acagtaactc gtaaacgtcg
    33601 taaaagagtg ctaaaattag caaaaggtta ctacggttca aaacacactt tatttaaaac
    33661 agcaaaagaa caagtaatga attcatacaa ctacgcatat cgcgatcgtc gtcaaaagaa
    33721 acgcgacttc cgtaaattgt ggattgctcg tatcaacgca gcagctcgta tgaatggctt
    33781 gagctactca aaattaatgc acggtttgaa agttgctgaa atcgacatca accgtaaaat
    33841 gttagctgac ttggctgtta acgatgcagc agcatttact gcattggctg accaagcaaa
    33901 agaagctttg gctaaataag ctaaacaatt ataaagagga aagaagataa cgaaaagtta
    33961 tgttctttcc tcttttttta tttacaatcc tccatcaaat gaaacaggac aataacgtat
    34021 aagtctaaaa tagcataatt aaggtttttt aattgaaaac tgaacattta tggtcaccct
    34081 ttaatgaaag cgctaactac ataagttaga atgagtttga ctgatatatt agtttgctta
    34141 tcagaaaaac aaaatggacg gaggaataac atgagtgata ttattattgg tattttgtta
    34201 gttatctcat tctttttcat ggtctggtac tgtgtaaaag gctacaactt gatggtcggc
    34261 tttgccatca tggctactgt atggatggga ttagcgctag tcggaaacac gttttcacca
    34321 aacccggcga tggaagggca aggagtaatt gatgtgttga cgcatatcta tacgacgggg
    34381 ccagctgagt acgccaaatc gatcttggta aatgtcttct ttggtgcctt tttcgggcgt
    34441 gttctagtag atagcggaat cgcagctacc ctgattcgaa aggtagttga acttggaggg
    34501 gacaagccaa gaatcacgat gagcttacta tgtattgtaa ccgctgttat attcatgtcg
    34561 atgacaggaa tcggaccagt gatttctatt gcagttattg tgttgccaat cttgatgtca
    34621 ttaggtattt cagtaccggt tgcactgttc tcatttatgg gctcgattat ggctggaatc
    34681 tttgctaata tcgtcaattt caaacaatat caaacgattt atgctggttt caatccagcg
    34741 gctgaaagct atacttataa tgactatttc caaattggta tgattgggat gattgtaagc
    34801 ttagttgtgg tactaacggt cgctaatata tcaatgaaca aaaagaaacg ctatgcaatg
    34861 gcagcaaacg taccagctga aggtggcgac gcaccaatga tctcatggtt agccgtatta
    34921 ttaccagttt taggggtcgt tcttttagat cttccaatca tcttaggttt tattctagca
    34981 ggtatctggg cattgctgtt tactggaaaa ttgcgcggag gttataaaga aatctgtcgt
    35041 cagtttgcga aattatttac agatggcgca gtagatgttg caccaatggt tggtttcttg
    35101 atgaccttag cgatgttcaa taattcagct gcgtatgctt ctccttattt ttcagctatt
    35161 tttggagatt ggataccgca atcaccatta gtcttggcaa tcgtatttgc tatattgaca
    35221 ccactaggat ttttccgcgg tccaatgaat ctagtcggtt caggctcagc tattttagct
    35281 gtcgtattag ctgttaatcc aacgatgtcg ccagcctttt tgttcccgtt atttgcaatc
    35341 acaacgattg ctcctcagca tttagatatt acacaatctt gggttgcttg gggattaggt
    35401 tatacaaaag taacttctcg agaatatatg aagaaatcca tcccaactgg ttggatcatc
    35461 ggagcgatct tatgcctgat cacgttctta ttgtacggga acgcctagta aacaaaacgt
    35521 cgataaaaac gattagatga atggaggaaa agaaaatgaa acgttttgtg cgaatgggaa
    35581 ttgatgttgg cggtacacat acgaaagcag tcgcaatcga taatgcgacg cacgaaatca
    35641 tcggaaaatc ttcagtgaaa acaacccacg atgatgtccg tggagtagcc gcaggtgtcg
    35701 ttcagtcttt tcaaaattgt ttgcgggaaa ataatatcag tccagaagat gttgtgtttg
    35761 ttgcacattc taccacacaa gcgactaatg cactgattga aggagacgta gcaaaagtcg
    35821 gcgtaatcgg gatggcaaaa ggtggattag aaggtttttt agcaaaacga caaactagat
    35881 tgaacgatat cgatttaggg aataagaaaa aaatagagat tgtcaatgca ttcttacctg
    35941 tcaaacactt aaatgtagac cgtgtttcag aaacgatttc ttctttagaa agagaaagag
    36001 cggaggtctt ggtttcttct atggcatttg gagtagataa tggggaacca gaacgagttg
    36061 tttatgaagc agcatcggta aaatcgatcc ctacaacgat ggcttctgac atcacaaaat
    36121 tatatggatt gacaagaaga actcggacag cagcaatcaa tgcatctatt ttaccaaaaa
    36181 tgctagatac ggcaacctct acagaagatt ccgtacgaga agcaggggtc aatgtttctt
    36241 tgatgattat gcgcggagac ggcggagtaa tggaaatcaa tgaaatgaaa aaacgacctg
    36301 ttttaaccat gctttccggt ccagcagcat cagtcatggg ctctttgatg tacttgagag
    36361 cgtctaatgg tgtttatttt gaagtaggcg gaacaacaac caatatcggg gtcattaaaa
    36421 atggacgtcc agcaatcgat tattcaattg taggtggcca cccaacatat atctcttcat
    36481 tagatgttcg ggttctaggt gtggcaggcg gttcgatggt acgggctaat cagtcaggaa
    36541 tcatcgatgt cggtccacgt tctgcacata ttgccggtct agattatgca gtatttacgg
    36601 agacagaaaa aatcaaaggt cctaaggttg aatttttctc tcctaaagaa ggagaccctg
    36661 ctgattacgt caaggtagtg atggaagacg gagaagaagt gactattaca aatacatgtg
    36721 cagccaatgt ccttggatta gtgcaagaag aacatttttc ttatggaaat gtcccatctg
    36781 cacgaaaagc catccaagca ttagctgatt attgtcatac gacggttgaa gacatcgcag
    36841 aacagatcat ggaaaaatcc tatgctaaga ttgaaccggt gattttagaa ttggcagaca
    36901 agtatcactt ggagaaagat cagatttctc ttgtaggtgt agggggcggc gctgcctcat
    36961 tgattactta ctttagtaat aaaatgggtg tgaaatattc gattcctgaa aacgccgaag
    37021 tgatttcttc tattggtgta gcacttgcaa tggtccgaga tgttgtagaa cgtatcatcc
    37081 cttcgccaag taaagaagat atacgatcgt tgaaaaatga agcgatgaat aaagcgattg
    37141 aatcaggcgc tacaccagaa tcgatcgaag tccacgtaga aatcgatcca cagacttcaa
    37201 aagtaacggc tatcgctact ggttctacgg aagtgaaagc aaccgatcta accaaggaga
    37261 tcacaacaga agaagcacta gagcttgctg cagaggatat gcgattaaat aaaaatgaag
    37321 tttgcttatt ggaaaataca cctttctttt atgtatgcgg cgaacagaat cgttcaaaaa
    37381 atgctggaag tcttcggatc atcgatcaaa aaggatttat caaggtccaa cgtggacatg
    37441 cttcatgtat gaaaacaact gcagccaatt atatgacagc tgtcgaacaa ctttgggaag
    37501 atatggcagt ttatcaaact gaattgattg cccgaccaga attttatctc tgcttaggag
    37561 caagagtctc tgattttaca gcgacggatc tggaacaact acagcttttg atggatctgg
    37621 aagtatctac tatggaaccg gaggaagaag tgatcgtcgt tgccggaaat atcaaacaaa
    37681 cataagttag aagagttact aaacgaatta caacagatcc ccgaagaaat ttggggattc
    37741 taccagtttc ggcgagattt attttggaaa aagattcctt tgtccaagca gaaaattctt
    37801 atacaacaat caatcgattg tggtatcgaa acggcatgta gcatcaaaaa aaagtaccct
    37861 tttgccgatg taggagaaat ttgtgaacaa atggctgttc caatcgtttc ctgtgaatca
    37921 gagcaaataa acgaacgaat cacttttgca acttatgcag aagatgaagg gattcgattg
    37981 atgacggagc cgttagaaaa attaaaatgt tcaggactag cttcgatctc taaagaaaca
    38041 gcgcaagctt tgattattgg acatgaacta tttcaccaca tcgaagcttc tgttaaggga
    38101 atttatacgc aaagcgaaaa aattgtgctg tggcggttgc ctttttatac acatcaatca
    38161 aacattcgtg cattgagcga gatagcagcg atgagttttt caaaagagat gaatcaaagc
    38221 gatttttcgc cttatgtatt agaggcagtc ttactttggc catataatga aattcgtagc
    38281 caagggatct tagaagaaat aaaaaaaata gaaaaaagat gtacggagta tgatttagat
    38341 tacaaataaa gagactgtga caaaagtcgt gtcacagtcc tttttttccg aataaacgat
    38401 gttctcctgt caactcctcg gtcacaagtc aaaatattca acaaacatga gaagctgttt
    38461 tttgaaattg ttccttgtga ctcggagatg aacggcaggc tcacgacctc ttggaaaacg
    38521 gtgttcaaaa gcttgcatct gcggtaataa gtccagccaa gttaaaaaca taagaagcta
    38581 tttttacttg gctgttctta ttacttgatg cagggcagct ttttcacaac ctctcaataa
    38641 acggtgtgca atcagctgac cctcggtatt agctcaaaaa aaacggcaaa atatgaggaa
    38701 ctattttgcc gtttctttct ctaatactca ggtcaaaacg ctgattccaa aacctcttat
    38761 ttgatgggtc tgtcctgaat atcttcaaaa taatcggggt aattatgaat cacgtattct
    38821 tgctcctcga taatcatatg taaatgcatc gtgcaaagaa atccgacttc atcaaagtta
    38881 tgatcaatca ttgattgaag cattgtctga tgttcatcta atactcgacc ccagtctaat
    38941 tctgaaatcg tcaaacgtaa ccatctgaaa cggttcaagt gcgtactata actttctagc
    39001 caatcccaaa tttctcgttt tccagcaatt tcataacaag ttcggtgaaa atcagtatcc
    39061 aaatcaaaaa aagctttttt attttgagcg attactgcct gatcggtttt tccaactttt
    39121 cccgcgtata acgggctaat gaagcagatc ggatatcgat ttttgaaaca taagtgccgg
    39181 actgtggaat ggtttttaca agctcttgat tgcgcagttg gatcagtgct tctcgaatcg
    39241 gtgtacgccc gatagctagt tgttcttcta acactttatc ggagatttta cttccaggtg
    39301 ctaactcgga ataaatgatt tgtttacgta tagattcata agcttgctgt tgcaaattat
    39361 tgataaccat ttaaccttcc tttctatgca gatataatct attataacat aaatcgctta
    39421 caaatcgtgt gggcataaaa acacagtctg caaaaaaagc cctgataggc atgcctatta
    39481 gagcctcgaa aagaaaaata ttgaatcaat ctggtcgtac ctcttgtatc ggtttgacac
    39541 gaccgccgat tcttttagca aaagcttcgg attctttttt gtctttgaaa atgagcagat
    39601 tgtctaagtt tttttcccga gtgcgacagc cagttttatc gatgtaaccg tgcattactt
    39661 taacgacata catggggatc acctgctttt ttcttttcat tatacgaact actcgacaca
    39721 atacaagaaa aatgcttaga cggtctttat taagaattta catcatccaa agaagcgtac
    39781 gcttggaata actgatctaa ctccggattg actttgctca gcttcactaa tcgttgcgaa
    39841 tcagaaagta aaaaacagtg tttactactg ccagtagttt ttaatttttt gtcttcagtt
    39901 cccacaattt cgtagctaaa atccaaccgt gtccccgtat acttttggat agttggatgg
    39961 atgctcactt tttctccgta atggatcatt tctttatagc tgcaatttac ttccagaacg
    40021 gggatgatga tcccagattc ttcgattttt ttatagggaa accctagatg taccaataag
    40081 gctacccgag cctcttcaaa ccagcggata taattgctgt gatgaataat ccccatttga
    40141 tctgtttcat aataaaaagg ttctcgcaca taacctgtaa atttctccat gactcatgcc
    40201 tcgttttcca ttgatttttt acaaaaataa ttcatccatt tcggaagtgc ttcgctgatt
    40261 tgtgtcggca aaacaatata ttgttctttt gccagctggt ctccaatgaa actatgaaga
    40321 taaatagctg ctgcaatcgt ttggtcattt tgaggaaact gggctaaaaa tcctgtgatc
    40381 atcccagcta aagtgtcacc catgccgccc gttgccatag cagcagaacc taaaggattg
    40441 gtgtagaagt gctggtgacc ataaattttt gtctcatgac ttttcaaaac gagcacagca
    40501 ccgatttcct gttgcttctt tttgttttct ttatcccgtt gttcttgtat cggtagagaa
    40561 ctcaaccgtt gccactccat ttgatgaggt gtaagtacag tttgttcggg atagggtagc
    40621 aaaagatgat tagcagcaag taaacttaaa gcagagccat caatcaccag ccattgttct
    40681 tttgattggt tttctagtac ttgtttgaaa cgttccaaac tcttagaaga agtacccaat
    40741 ccgggaccaa tcaagagtac atctgcttgc tttattacgg aaagaaactg gtcagtatcc
    40801 gtccaaacta caatcattgc ttctggcaga tgactgtgaa gagcactccg atttttttca
    40861 tcagttacta cagtcgtgag acccgctccg ctgtgtacgg cagctaaagc actcataatg
    40921 attgctccgc catattgttc attgccgcca atcaaaacga tacgtccaaa tgttccttta
    40981 tgtgaaattt ttggacgagg tgtgatgact cttttcacta gttgttcgtt tatcagcatc
    41041 taaaaacctc cttttactca ttatagcgta tatttttttt agagaaaaac agataagaaa
    41101 aggaattgtc agattttttg aactattttt ttctgtaatt tgtggtatca tgaacacgaa
    41161 gacttaaata agtggaggat taactttatg acaattgatt ggcaaaaaga agtagaagca
    41221 cgtaaagaag acttgcttga agacttgaaa aatcttttac gtgtcaacag cgagcgcgat
    41281 gactcaaaag taacaccaga tgcaccattt ggacctggac ctcgcgacgc attgaaacat
    41341 atgttagctt atggcgaacg tgatggattt aaagtaaaaa atgtcgataa ctatgcaggg
    41401 catattgatc ttggcgaagg agacgaaacg ctagggatat ttggacacat ggatgtcgtt
    41461 cctgcaggag atggctggga cacagatcct tatgaaccag taatcaagga tggaaagatc
    41521 tttgcacgcg gatcaagcga tgacaaaggt ccaagtatgg cagcttacta tgcgatgaag
    41581 atcattaaag aacttgactt gaaactatca aaaaaagttc gcttcgtagt cggcagcgat
    41641 gaagaaagcg gctggggcga tatggcttat tatttcgaac atgaagaaga accagatttt
    41701 ggtttctcac cagatgctga attcccaatc atcaatggtg aaaaaggaaa tgtttcttta
    41761 gctttacgct tcaaaggcga caatgcagga gattatgtct tgaaatcttt tgtttccgga
    41821 cttcgcgaaa atatggtgcc aggaacagca actgcagcac ttcaagtacc aagtgcagat
    41881 gcagctatcg cgatggaaga agcattttac caattcatcg aagcaaatcc agtaagcgga
    41941 acgattgaag cggacaatac gtatgtaaaa atcgaattag ttggtaaagg cgcacatggt
    42001 gcaagcccac aatctggtat caatgcaggt tctttcttgg cattgttctt agataactat
    42061 gaattcctag gatctgctaa acaatttatc catgtagcag ctgcttatgt ccatgaagat
    42121 ttttatggag aaaaactagg agtcgcttat gaagatgaaa aaatgggcaa attgacaatg
    42181 aatgctggac tatttgcttt tgaagaaaat ggtacagagg aagcgaactt catcaatatg
    42241 aatttccgtt ttccaaaagg tgtaacagta gacggattgc aaagtgacat cgaacaaaca
    42301 gtggggcaag aaggcgcaac agttactcga ggtgctcgcg taatggaacc acattacgta
    42361 ccaatggatg atccattggt ggctacatta ttgcaagtct atgaagacca cactggagaa
    42421 aaaggctacg aacaaatcat cggtggcgga acttacggac gtttgttgaa acgtggcgtt
    42481 gcttatggag cgatgttccc aggatatact gatacaatgc atcaagcaaa cgaatttatg
    42541 agtcttgatg acttgttcag agcaacagca atctatgcag atgccatcta tcgtttggcg
    42601 aaataattaa ttaaaaagag gatcaagaat tgcaaattat ttttgcagtc ttgatccttt
    42661 ttttactttc tactgtggta ttcatgataa acatgatata gattcaattc atattctttc
    42721 ttagcgttcg tgacgactgt atccaaaatc aaccctgtta ctaatgaaag aagtgctaaa
    42781 gtcatcaatc cagtacttaa aatcgcagaa gggatgcgtg taataaagct tgtcagcata
    42841 tattcgcgaa tcacaggaat ccccgtgacc aatccaaata aaaagaagaa gatggtccaa
    42901 atcccaaaga aaagcaaagg cttataatct ttaaacattt taataatcat catgatcact
    42961 ttgaatccgt cagagaatgt attcaatttt gattcgctgc cttcaggacg atcacgataa
    43021 tcgattggga tttcaacgaa cttgaatttt ttatctaaag catggatcgt caattccgtt
    43081 tcgatttgaa aaccagaact cataatagga aaacttttga caaagatacg attgaatcct
    43141 cgatagccgg tcatgacatc aagaattttt gttttataca ttctagtaat tgtatttcta
    43201 acaaggttat ttccaaaatc gtggaaaggt ctcttattct catcaaagta ggttccattt
    43261 gataggcgat caccaatgac catatctgct tcaccagaac gtaatttctc gagcaaacca
    43321 tgtacagctt ctgcaggata agtatcatcg ccatctacca ttaaataata gtcggcatcg
    43381 atatcaaaga acatttggcg gatcacattt ccttttcctt gacgaggttc tttttttacg
    43441 attgctccac cttgaacggc caattcgtat gttcgatcgg tcgaattatt atcatagaca
    43501 taaatatctg cttctggtaa ttctcgttta aagtctgcaa tgactgttga aattgttgct
    43561 tcctcattgt aacaaggaat cagaacagca attttttctt gttgttccat ttttcactct
    43621 ccttaactat agaaaacaaa agctaaatta aaaatacctc ataatcaaag gaaatgctag
    43681 tttttcccgc taaatatcat ttatttaaaa agaaaatact ggaatatatg tttggaaagc
    43741 tctatctaaa aaaccaccca ctacaaaaga aggacatgat acctctcttt tgaatagtgg
    43801 gtgcgtattc gttctctcac ttttttgacg tattaatctg ttgcaccttt ttttcttgaa
    43861 atttctaata cggttcctgt atgagcatct gctaaaaatt cataataaac agtttcgcca
    43921 tcttctattc gagaaagacc tccccgataa gcactcgacc gaacggcgaa tttcctaata
    43981 ggttcctttt caaaagagat ccaagaacct tcgattgcac cttcttttag aaaagatgac
    44041 ttgatatttt caagtacttg gtctgctgac aatacttttt tgcgatgata ccaaatcgtt
    44101 gaagctaccc cgctcaataa tcctagaccg attccaactg ctaacccgcc tttaaaatag
    44161 cttagttcgc tttcttcata catgtggaca tacctccttc ttctcacttg ttactccttg
    44221 tgcttatttt accacactct catattttct ttgaaataaa taaccgctac cagaaaaaat
    44281 aagctataat aaatacgatc ggtctgcaga aaaaatcata ttttatccgc agatcaatat
    44341 aagtctgaga ggagtttagt ctgaaattta gacgaatagc atatggaaga aaaaacattt
    44401 caacgaatca aagagttaac agaattacaa ggaacaagcg gttttgaaca agatgttcgc
    44461 gcttatatgg aaagtcatat ggaaccgctg gtagatgagt tacagttaga tggtttgggc
    44521 ggcatttttg gtctgcgcca tcatgaagaa gcggatgcac cccgtgtaat ggtcgcagca
    44581 catatggatg aagtcggatt catgctgaca caaatccaag aaaacgggct ttttaaagtc
    44641 gtacctctag gcggctggaa tccttacgtt gtttctgctc agcgttttac acttaaaacc
    44701 tctactggta agaattatcc atgtatttct tcttccgttc ccccacattt attgcgagga
    44761 acaagcggac aaaaatcagt agaagtaacc gatattttgt tcgatgctgg gtttgaatca
    44821 agagaagagg caatgagtta cggtgtcctt ccaggagaca caatcgttcc ttacgctgaa
    44881 acgatcaaaa cagccaacgg aaagaatatt atcagtaaat catgggacaa ccgctatggc
    44941 tgtacaatgg tattagaagc tttagaagcg ttgcaaaatg aaacattagg tcatacattg
    45001 attgcaggcg cgaatgtcca ggaagaagta ggcttgcgtg gttctaaagc ttctgtcaat
    45061 aaattcaagc cagatctgtt ctttgcagta gactgctctg cagcagatga tacagtgacg
    45121 aaaaatggca cattcggaca tttaggagaa ggtacattga tgcgtatcca agatccaggt
    45181 ttgatcatgc ttcctcgttt gcgcgagtac ttgctggata tcgctgaaac aaacaatatc
    45241 ccttatcaat actttgtttc aaaaggcggt acagatgcag gtgctgctca tacacaaaac
    45301 gaaggaatcc caagtacagt gattggcgta gtgggacgtt atatccatac gcatcaaacg
    45361 atgttcagta ttcgcgattt tgaagctgca cgagaaatgt tgattcaaac actgaaaggt
    45421 ttggataaat caacagtgaa tacgatcgta tacggaaaat aatgcgatag tgaaactata
    45481 aaatctggca aaagattgct ttttgccaga ttttttttat aaaaagagga tcaatgtttg
    45541 ttagttcgaa agaaaggtgt ataatttaat tgaaaaatac ataaacagaa agtagaggac
    45601 aaagaatgat tatcccaaat agtttagaag aattagcagg ctacgtagaa actggaaaga
    45661 gtgtattttt ctttactgcc ggctggtgcg gagactgccg ttttatcaaa ccgcaaatgc
    45721 ctgaaattga aaatgacttt tctgattggc aatttattga agtagaccgt gacaagtaca
    45781 tagatgtagc cgctgaatgg aacatttttg gtatcccaag ttttgtcgtg atccaagacg
    45841 gaaaagaatt aggtcgtcta gtgaataaag atcgtaaaac aaaacaggaa atcgaatcgt
    45901 tcctagaaag tgtaacaaaa ggctgacatc tgttaggagg ggtcaagatg aatcaagaat
    45961 ataagaatat tttagtaggt atcgacggta gtgaacaagc acttgctgct ttcaaaaaag
    46021 cggtagaagt ggctcgccgt aataatggga aagtatatgt agcaaacgta atcgatcagc
    46081 aattttataa ctttatgggc tatgcaccta ttgatcaaaa tctagtcgat cagcaaactg
    46141 aaacagccaa ggaaatgatc gaagaatgta aagaatatgg gaaatctgtt gattacacaa
    46201 atatagaagg aattattgca tatggttctg ttcgtgaatc catggcagtc aaattgccaa
    46261 aaaaatatga gatcgatcta atcatggttg ggcagtcagg tctaaatgca gtcgaacgct
    46321 ttatgacagg aagtgtagcc agctacgtga tacgtcattc accttgtgat gtcttgatcg
    46381 tttctgacga agaagaacag ccaagtaatt aagcaagtgg aacttgtacg acctttttaa
    46441 tcaattaact aaaacagtaa agggactgtg acaaaagtct tgtcacagtc ccttgttacg
    46501 aataaatggt gttccagaag aggcttcttc ggaaataaag catgaaaaaa atttcatgca
    46561 gtgaatgcaa ttttttgtta agataaatct cagcaaagga taatggagga aagaacatga
    46621 tttttgctta taacaaagca cacgtcggag acaccttgat ggttattata gccgacgata
    46681 aaggaacaga aaacactgtt gaacgcaaat ggaatgttgc tcggatcaaa gatgaacaag
    46741 gtcaagttgt tgcttggaac tttttccata tctccgatca tctaacaatc gaagggaacg
    46801 gccaagtaag cttaacagat gaggaattag cgaaattgaa tcgattgatc aaagaagcag
    46861 gattcgaaga acagcttgaa gctgatcatg aaccgaagat cgttgtcggg tacgtaaaaa
    46921 catgcgtccc acatcctgat tctgaccatt tatcgattac tgagacagaa gtagacaatg
    46981 gtacagtatt gcaaatcgtt tgcggtgcac ccaatatcga agctggacaa aaagttgtcg
    47041 ttgcaaaacc aggagctatg atgccagatg gaatgatgat ctggccagga actttgcgag
    47101 gggtagatag ctatggaatg atctgttccg ctcgtgaatt gcatttgcca aatgctccag
    47161 caaaaaaagg aatcttagta ttgcctgagg atgccgtagt cggagaagca tttccaaaat
    47221 aaagaggttg tgacaagtct ttgtcacaac ctctttttta ttaattttca ctattttgat
    47281 tttgttttaa tgccgattga tcgatcgtca attcaacagt agttgttttt tctttcgagc
    47341 cttcatagta agtgattttg acagaatctc ccactttttt cttatacaaa gcagattgaa
    47401 gttctacacc agaagaaact tctttgtcat cgatcttagt aatgacgtcg tattgtttca
    47461 atccagcttt ttcagccggt gtagctgttt ggacatttgt cacgatgaca ccgttagtta
    47521 cagatgaagg aatcttcaag atttgttctt gttgctgagt agaaacggca gataagtcga
    47581 ccattgtgat acctagagct ggacgtgtca cttttccgtc tttttccagt tgattgatga
    47641 tattcactac atcgttactt ggaatagcaa atcccattcc ttctacgctt acattagaag
    47701 tagattcaga agtacttgcg atcttacttg agttgatacc gataacttgt ccttcgatat
    47761 taactaaagg accaccagaa tttccagggt tgattgctgc atctgtttgg atcgcattga
    47821 tattgactgt ttcgttcgat tcattcgtac ttgtcacttg tcggttcaag gaagaaatga
    47881 ttcctgaagt gacagaattt gcatattcag atcctagtgg ggaaccaatc gcaatcgcag
    47941 gctcaccaac cttcagagca cttgagtcac caaaagaggc aactgtttcg actttgtctg
    48001 aattgatctt caacaccgct aaatctgaat aagcatctgt tccaactaat tcagctttta
    48061 ccttcgtacc gtctttcatc aagacttcaa gaccttgctg gccatctact acgtgattat
    48121 tcgtgactac ataagcagta ttcccgtctt ttttgtagat cacgccgctt ccttcactat
    48181 aagcttccaa attactatca tctgagctgc tactttcttc ttgctgcccg aatagtccgc
    48241 caaaaccgct tgattggttt tgactttgta agttgataac agaaacgaca gcgtcttgaa
    48301 ctttatctac cgctttggtg atatcagaat ctacattgac tttgacattt tccacaactg
    48361 tttcaccggc agaattctga ttgccgcttg tagcagtaga actattgttg ccagtgccca
    48421 tcgctgcata aaaaatgcca gctgtcagta gtcctccaac gatccctcca acaagcccca
    48481 gacctaactt acgccagagg ctattatttt tacttttttt catctttggt gtcacatttt
    48541 ttctatccat gtgttcctcc tccaattaca ttcatttatc tactgttagt atagtcttat
    48601 ttgttgactt tagtctactt tgagactgtg aactttttat gaaaaacttt aggaaaaatc
    48661 attgttttca gatgaaaata tttgattttc tttttccaca gatactgtgt aaaactacgc
    48721 ggataggatt ggaaaaataa gggataaaac atatccacag cctgtgtata aagtggataa
    48781 attcttataa aacgtatgtt tgcctaatga atgtgatgaa ataaggtaaa ataacactgt
    48841 tttctgtgga taaacctgtg gatgttgtgc ataactgttg gggaaatctt tttaacaaaa
    48901 atagccaaaa taaacatata gacgaaaaaa ttgattataa taaacaaagt gagcatgaag
    48961 accaaaggag agaaaacatg aatatcaaaa ttatctcagt aggaaaatta aaagaaaaat
    49021 acctgatcca aggtatcaat gagtatgtca aacggctgaa tgcctatgca aaaatcgaat
    49081 tgatcgaagt tcctgacgaa aaagccccgg agaatttaag cgaagcgcaa atgagacaag
    49141 taaaagaaaa agaaggggaa cggatcttag cgaaaatcaa agaacaagaa tacgtctatg
    49201 ccttagcaat tgaagggaaa aatcctacaa gtgaatcttt tgctaaacaa atcgaccaat
    49261 taggtatcca aggaaaaagc caccttgttt ttgttatcgg cggctcttta ggactcagcg
    49321 aagccgtcat gaaaagaagc aatgctcaga tctcttttgg aaaaatgacg tatccacatc
    49381 aattgatgcg tctgatcctt gtcgagcaaa tctaccgtgc cttccggatc aatgcggggg
    49441 cgccttatca taagtgatgc ggtttttatc attgatccta aaaatcttag caagacaaaa
    49501 agtacgtaag aaagtaaaga ctaaatactt cggaggaaca aatgaataac aatgataggt
    49561 tattgcgatt gcgttatgcg attgatttga aagatacgga tttgattaaa gcttttgagc
    49621 taggcggtgt accactgact aaagaagaag ctcaggcggt actgaccaaa gtacaggata
    49681 agaacaaaga taatgcagaa aataatgtgt atgaaaaaac catcaacaac caagtttttg
    49741 acgcattcct aaatggcctg attctcttgg cgcgtggtcc gcaaaaagat aagccgatag
    49801 tagacacgcc gcaaaaaagc aaggaaatca aatatatcaa caatgtgttg ctaaaaaaat
    49861 taaaaatcgc cttgtctatg accactgatg atattttaga cgtttttgct gaggcagaaa
    49921 tctatccatc aaaaggcgaa atcggggcat ttttgagaaa agaaggccaa cgaaatttta
    49981 agccttgcgg agataaatat atgcgtaatt ttctcaaggg gttaggaatt tataatcgga
    50041 gaaaagtata aagaaatttc atgagaaatc aaaacaatgg ttgttttgat gagagctagt
    50101 ttttgtatga gattaaaata ttatcttaat cgaggagctg gattggtttt atgaatgatg
    50161 aatataagaa tgatgaagat aagatgcttt ttgaagagat agagaatcga tgtaggctca
    50221 attttgagct tcggggaaag atgtctttaa tacaacaaaa aaagtattta gcgaataaat
    50281 cagagtttac tctgggacat gttgaaaaat taatctcgga ttggattagt agtagaagcg
    50341 aatttacaaa aataaaacag ccgattaaat ttgacatgaa aaaacttttg ttaaataaga
    50401 gtgagatagg taatagagat caatatatta gagctaaagg gcaagaaata attgattcat
    50461 taggtgaaat gaggtcatac aattatttgt atgtaacaca tagagctgat ggaatggtca
    50521 ttactgtggg gaaatcttct tctaatgata tttttttaga tggagatctt ttttatcaac
    50581 tcaatacaaa tcacttgtct ggcactgaaa atataatttt aaggacggaa tatggcaatg
    50641 aaatatttgc aaaatatgat gagattttaa aaaattattt ggactgggct tggataattc
    50701 cggttgagtc aggagatgct aagaaactgg agagattatt gggcgatgaa ctaattaata
    50761 aaaaagtacc aattttaaat tattattccc atagacaata aaaggctatt tttcatgata
    50821 atactagtta taactgtaaa aatggaagaa aatctgggaa agaagttttt aaataagtgt
    50881 attgttcgat tttaataaat aataagcaat accatccgtc tgtgttgcgc aacatcgtac
    50941 tacaatgaat attttttcac aaaaagaaaa tcatccatcg aatgaatgga aggttttagt
    51001 atacacgagg ttaatgcccc ctcttttata atcagaggag tgaggttttt tctatgaatg
    51061 tttctatttt cttattgcta gtctagtttc tcttacgatg aaattgggat tctattccag
    51121 tttttattga tttgctgata aaataacttg aatggtggat ataaacatga taaataagag
    51181 aagaataaca aaacaaggtt gtgaaatgat tctcaaatga atataataga aagaaaaagg
    51241 aggaagaatc aatgaaaata gcaattgcag gcgctggcgc aatgggaagt cgctttgggt
    51301 taatgcttca ccaaagtggg aacgaagtat tattaatcga tggctgggca gaacatgtcc
    51361 aacaaatcaa agagcatgga ttacaagcaa attttaatgg taaagaggta gaagcaaaac
    51421 taccaatcgt tcttcaatcc gaagtagaaa aagaagatca agttgatctg attattctat
    51481 ttaccaaagc gatgcagctg gaaaaaatgc tgcaggatat ccaatcatta atcaaaaaag
    51541 atacagaggt cttatgtcta ttaaatggta tcgggcatga agatattatt gagaaatttg
    51601 taccaatgga aaatatctat attggaaata ccatgtggac ggcaggtctt gaaggtcctg
    51661 gtcaggtcaa attatttgga agtggttcag tagaattaca aaatttaggt gatggaaaag
    51721 aagcagctgc aaaaaaatta gcagacaaat tgtctgaatc aggattaaat gctcattttt
    51781 ctgacaatat tcactattct atttatcgca aagcatgtgt gaacggaaca atgaacggac
    51841 tatgcacaat cttagacgtt aatatggctg agctaggaaa aacatcgact gctcataaaa
    51901 tggtggcgac gattgtcaat gagtttgcca aagtagcagc agtagagaag attgaactag
    51961 atgtcccaga agtcattgca cattgtgaat cttgttttga cccggaaaca attgggttac
    52021 attatccttc aatgtatcaa gacttgatta agaaccatcg attaacagaa atcgattata
    52081 tcaatggcgc aatttctaga aaagggaaga aatatggtgt tgcgacgcct tattgtgatt
    52141 tcttgactga gcttgtccat gcaaaagaag atagtttgaa cgtaaaataa aggagagatt
    52201 gaatggaaac ttcacaaaaa atatcaccga aaatttttct gaataaagtc ctcgctggta
    52261 cagcaacagg aatcattatt ggattgattc ctaatgcagt attaggtgcc attttaaaat
    52321 attttagtgc gtatcccttt gcggtaacga tcgcacagtt agcagttatt tttcaactag
    52381 caacaccttt gatcattggt ggtttgattg ccttacaatt tggatttgat ccgatgagaa
    52441 tgatggttgt agccggagct tcttttgttg gttctggtgt agtcaaattc acacctgatt
    52501 tgggtgaaac gggtgtttac gttggtgctg gtacaggcga tattattaat acgatgctga
    52561 cagcatcgat tgctgtcggg ctgattttac tgattggaaa tagttttggg tcagtgtcga
    52621 ttgtgttaac accgattgtt gtaggtgtag gtgcaggttt acttggtttt tatttattcc
    52681 cttttgtaac agcaattact tctgcaattg gatcattgat taataacttc actaccttac
    52741 aaccgctgtt aatgtctatc ttgattggtt gttcctttgc ctttttgatt atctctccta
    52801 tttcaacagt agcaatcgga atggcaatcc aactagatgg tgtttctgct ggtgcggctg
    52861 cgatgggcgt agctgcaacc acttttgttt tagtagtgaa ctcttggaag gttaataagt
    52921 caggtgtgac aattgcgatt gctttaggcg ctatgaagat gatgatgcct aatctattta
    52981 gaaaacctgt gattcttatt ccttgtttag ttagtgcagt gattacagct attcctgtcg
    53041 ctctattttc tatttcaggt acgcctgctt ctgctggttt cggcgtggtc ggacttgttg
    53101 gtccgttggc ttctttagat gcagggctaa atggctttct tgttgttctt tgttggttag
    53161 tcatccctgt ttttgcggca ctaattactc aatttttatg cgagaaagta tttaaactgt
    53221 atgatcgaga agaagtcttc aaatttttag gctagtagat tttactaaga aattttcaat
    53281 caatggatgc gtaagtgaga tgtcaacaac atctgactta cgtttttttg cctttttgag
    53341 taggagattg atgctgacaa ctgaactctt cagtgccatt cgatttttta aaatgtagaa
    53401 gaaactcacc tttatgttat tgattgttca aaaggcaact agaataaaaa tatgtgttaa
    53461 aatgagaaaa aatttgattg ttggatgtat cgaataatca ctaaaaagta ggagaagaaa
    53521 atgatttttt tgcaaaaata tggtttttat tttttattat taggtgtgat tagtgattta
    53581 tcgacaccgt atatccttgg ccttttttat cccaaactga atcaaatgac taccgtaatt
    53641 agtgtgtttg gtgacgtaga tagtccagtc agacgtgctt tcttggtctg gtcagttgta
    53701 tctggacttt tttttgttct ttcgttgcct gcgttgtatc acctatttat tggaacatca
    53761 aaaacacttg caatacttgc tgttgcaaca gttggtttat atgggatagg tgattgtatt
    53821 tttactgggt tattcagtat caatacgaat gaaagctctt ggaatctatc gacttggatc
    53881 cataatatag gttctgggct aggctatgca ggctttctac ttttcccatt gttacttgtt
    53941 ctgctttatc gtcaaagtgg tcaaggtacg cttagccatt tttatcttgt tttaacagtt
    54001 attagtttac taattgcagg tctttacgga ttagcacgga ttccgtcgat tagtcagttt
    54061 gccttcttta agcaattggg cttctttcaa cgcttaagtt ttttctttaa ctatttgccg
    54121 atgatttgtt taagtttttt tcaactacga aagtagaaaa agcagtgtga agctgattaa
    54181 gtaaaagaat ttctctatgg gtaaccattc gtgtggatgt gttcgactaa gaatagagat
    54241 gaggagagcg aaaagcaagt tagtcttaac ttgttatgcg ttgtgctaaa tttcaggtag
    54301 tcattttttg aatgaataag aagaaaactt gaaagagggt gacttcatgt tagatgtgga
    54361 gcagatggaa atagaccttt ataatattat tttaaatcga aatacaagag aatgggaaag
    54421 aacacaattt gaagaggcaa aagaagacct agcaaaaatg tcgataaagc aggtgataga
    54481 aaaactagag gtcaacttgc gtccgctagc actacgagat aatttgacac cagatgcgat
    54541 ggatttttat ttaagaatca caggggagtc agcgagtgca aaggcttatg attatgccaa
    54601 acataagata acttcaccct tataccaaga acgggcgatt tttgccggtg gctgtttctg
    54661 gtgtatggtt gagccttttg aaacaaaacc aggtgtaatc tcagtgttat ctggttatac
    54721 aggtggagag accaaaaaac caaattacga tcaagtcagt ggtggatata ctgggcatgt
    54781 tgaagctgtt gagatcatat ttgatacacg tcaaataacc tatgaagagc tgttggagat
    54841 ttattggcaa atttcagacc ctacagatgc ctttggtcaa tttcaagatc gggggaaaca
    54901 atatcgttca attctatttg ttgttaatga aaagcaaagg caattggctg aaaaatcaag
    54961 agaacaactg attcaatcta accgatttag ccgtcctatc gttacagaga ttcgccaagc
    55021 aaagactttt tggccagctg aaaatcatca tcaacaattt tatcagaagc aacctaaaag
    55081 atataaaaag atcaagcatt cgcatcagct tcatttattt tttcagcgac atagatagag
    55141 gaaggttgtg gcgcaaagcg ttcagctccg acaaaataat gagcaactga caaaaatagc
    55201 ttttcatatt tttggacagt tatgaattat ttcgaggagt tgctttgaga acaccgagga
    55261 aaaggttgtg gcgcaaagca ttcagcttca agtcgcaagg aaacaggagg tatgacaagt
    55321 cttttgtcac aactcctgtt tttttactag cctttatttc catgtgaaag agaattcgaa
    55381 ttgtagaatc ttgatttttc tatggaattt tgtagagaat catcttgata attaatagac
    55441 acctaatcga attccacatt aatgatgaac taaattccgt ataaaagcgc aaacaataac
    55501 ta
//
LOCUS       DAZKKZ010000011        53891 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.011, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000011 DAZKKZ010000000
VERSION     DAZKKZ010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 53891)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 53891)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..53891
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.011"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(203..1345)
                     /locus_tag="ACG8LA_000709"
     CDS             complement(203..1345)
                     /locus_tag="ACG8LA_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFQ0203034.1"
                     /translation="MRKIANVYKDRKRGTWFFSATLGQDRFGKRIQVTRRGFKTQGEA
                     RRGLEELKQSFSDSQGIYLQGITFHDFYREYFFPWYKLGTVEKTYMKTDHILQRALDF
                     FGEMQVVKIRPIHIQEFQQFLSKIHVVKKGIEQPLSPNYIKQIFNKLRVVFKRAIVLE
                     IIEENPVDTIGKIKTQRPQVEFWTVDEFKKVYNSVYHGDFYEEFYKRLMRFIFVTGVR
                     SEELLALQWKDFDLINGRCSVNKSIYIRTRQDYEFAETKNTSSIRIISLDRQTVEDLK
                     TWKKTQQSIGKNIELVFSFDGLPPSPRTILSRIKKLAEIAGVKPIHMHGLRHSHVAFL
                     IEHNKNIYAISKRLGHASIKTTLDKYGHLYPETNQALANEITRFDI"
     gene            complement(1350..1535)
                     /locus_tag="ACG8LA_000710"
     CDS             complement(1350..1535)
                     /locus_tag="ACG8LA_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HFQ0203035.1"
                     /translation="MKTATRKDLINLGFSQYYANKIFKECKELLVEKGYFFYRNSKIK
                     RIPISILEEVLHISWEE"
     gene            complement(1889..2134)
                     /locus_tag="ACG8LA_000711"
     CDS             complement(1889..2134)
                     /locus_tag="ACG8LA_000711"
                     /inference="COORDINATES: protein motif:HMM:NF024059.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0203036.1"
                     /translation="MVDKSKKRQYLLVPLSIILSALEGDPISIKMILKHYHSYMAKLC
                     LTNGFNEVGQFVTYVDEYMISQLEIKLIEAILKFKIN"
     gene            complement(2128..2529)
                     /locus_tag="ACG8LA_000712"
     CDS             complement(2128..2529)
                     /locus_tag="ACG8LA_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010818872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HFQ0203037.1"
                     /translation="MQQHYNDISIQHQFDAYCKKVLRNEAKSIRKRNANIKDNEEPLA
                     DSNEGRYSQTHFDEQDVYFLFGMEILISDQKLSAAIDQLSEIRRKIILLYYFAGFNDA
                     EIGKILNMSTSGIWYQRKKAVEQLKMGYDLW"
     gene            complement(2716..4524)
                     /gene="uidA"
                     /locus_tag="ACG8LA_000713"
     CDS             complement(2716..4524)
                     /gene="uidA"
                     /locus_tag="ACG8LA_000713"
                     /EC_number="3.2.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucuronidase"
                     /protein_id="HFQ0203038.1"
                     /translation="MLYPIMTETRQVIDLSGLWRFKLDTNDDLQEELALEPINEKESY
                     PISVPSSYNDLFETENIRNHVGWVWYEKEVTLPKRLLEERLVLRFGSATHEAKVFLNG
                     KFITQHKGGFTPFESEINRFVKDGNNRITVAVNNIIDDSTLPVGIMKETVQENGDIKK
                     ENLVNFDFFNYAGIHRPVKLYTTPKDYISDITINTRITDLDASVEFNIDTEWTGKILI
                     AIYDEEAQLVAEAEGKKGMIQLKNPIFWEPLDAYLYSMKISLIDDNKVIDTYTEEFGI
                     RSVQVTNGKFLINNKPFYFKGFGKHEDSYVNGRGLNEAVNIKDFNLMKWIGANSFRTS
                     HYPYSEEIMRLADREGIVVIDEVPAVGLHLNFMATLLDDNVEKHNTWKEIRTENSHKT
                     VIKELIERDKNHPSVVMWSIANEPDSDSEGAKEYFEPLVELTKELDPQKRPVTIVTYL
                     KSTPDVCKVGDIVDVLCLNRYYGWYVSGGDLAHAKYLLKKELDGWMERCPDTPIMFTE
                     YGADTVAGFHDTVPTMFTEEYQVAYYEANHEVIDTCENFVGEQVWNFADFATSQGILR
                     VQGNKKGIFTRDRKPKMIAYYLQKRWSSIPNFSYKK"
     gene            complement(4547..6313)
                     /locus_tag="ACG8LA_000714"
     CDS             complement(4547..6313)
                     /locus_tag="ACG8LA_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 3 N-terminal
                     domain-containing protein"
                     /protein_id="HFQ0203039.1"
                     /translation="MTIKVDLRKKPYNLDEDAISWIEETIDSMTLEEKIGQLFVNMGS
                     SRDKNYLSNMVNQYHIGAVRYNPGTADEVYDQNYILQTESKIPLLIAANTEAGGNGAC
                     TDGTEVGVEVKIGATNDAKYAYELGRVSGIEASAIGCNWSFAPIVDINRNWRNPIISS
                     RSFGQNPDKVLELSLAYMKGIQESGILPAAKHFPGDGIDERDQHLSFSINSLGTEEWD
                     NSFGKVYSGLIEAGLPSIMAGHIHMPAYSKHFNPDLKDEDLLPATLSKELITDLLRGK
                     LGFNGLVVTDASHMLGMTGAMKRSELLPTSIAAGCDLFLFFNDPDEDFNYMMEGYRKG
                     IITDDRLLDALKRILGLKAKLGLHKKAKEQILLPKQEALEKIGLIENKSIFKEVADQA
                     ITLVKDKQDIWPIVPEKYKRILLVDVHGVKGGFGEVVAGNRPQAIDLLKQILSAKGFE
                     VEKYISPEEELKGLSQEEKIKNIAGIYAAKRPIKNLTKKYDLIINIANVNPGTVQRIV
                     WPASKGTPDIPFYIHEIPTIFVSVQCPFHLADVPQVKTYINTYDGKQETLEILVDKLM
                     GLSEFKGVSPIDAYCGLKDTFI"
     gene            complement(6326..7120)
                     /locus_tag="ACG8LA_000715"
     CDS             complement(6326..7120)
                     /locus_tag="ACG8LA_000715"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFQ0203040.1"
                     /translation="MNNWIFCIDSDGCVMDTMTYKHNLFFGPIAAEIFDVHHREKFLQ
                     DWNNINLYSETRGINRFLGLVKTLEKNDVTSINRLKHWVSLTKELSNPSLKREIEYSQ
                     SEDLLKALKWSEEVNQQISQAKGLDKPFLSARDTIKALKKYGKIIIVSSANKEAVQEE
                     WERHELLSLVDELCCQDKGKKEDIIRSVIENGCDLDKILMIGDSPGDLEAANKNKVFF
                     YPILVNKEKESWENLRTDVLFKCLSGDYVDIEQKYIDTFWKNLTNK"
     gene            complement(7130..8506)
                     /locus_tag="ACG8LA_000716"
     CDS             complement(7130..8506)
                     /locus_tag="ACG8LA_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFQ0203041.1"
                     /translation="MERKFGIRDKIGYMFGDFGNDFTFIFASSFLMIFYTKVLGISGA
                     AVGTLFLVARFIDAVTDVTMGRIVDRSKATKQGKFKPWILRMSGPVALASFLMYQTSM
                     ISASMSVKVVYMYVTYILWGSIFYTSINIPYGSMASAITSITEERTMLSTFRNVGATL
                     ASLVIGVLTPLFIYTRDDSGAQIVRGGSTFTIVAGIFSICALICYLICYKLTTERVRI
                     DQSQYKVSLLKSLKGLVKNRALLSIIGAAIFLLLAQLLIMSMNNYVFPDYYNDAQGIV
                     LMNFINPILVLIVVSPLTLFLSKKYGKKELASVGMFFSAIVYLILFLIKASNMYVFLI
                     LSSVGYMGLGVFNTVIWANITDVIDDQEVKSDQREDGTVYAVYSFARKIGQALAGGVG
                     GWTLSIIGYDSLANVQTGDVLEKLYNASTLIPSICFLIVGLILFFLYPLSKDKVLENC
                     ELLKQKHK"
     gene            complement(8626..9273)
                     /locus_tag="ACG8LA_000717"
     CDS             complement(8626..9273)
                     /locus_tag="ACG8LA_000717"
                     /EC_number="4.1.2.14"
                     /EC_number="4.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016829 - lyase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 2-keto-4-hydroxyglutarate
                     aldolase/2-keto-3-deoxy-6-phosphogluconate aldolase"
                     /protein_id="HFQ0203042.1"
                     /translation="MKKVEILSKLEAAGVIAVVRGKNKDEAIKAINSIIAGGIKGIEL
                     TFTVPNAEEIIKEIAKKYADQKDVIIGAGTVLDAFTARIAIMAGAEYIVSPSFDRQTA
                     EICNLYQIPYLPGCMTITEIKEALTAGVDIIKLFPGSAFGPSIVKAYQAPLPHVNIMP
                     TGGVSIENLEDWFEVGVVAVGVGGNLLASVEKGDFEEVSRVASKYIDKFYEIKNY"
     gene            complement(9357..10784)
                     /gene="uxaC"
                     /locus_tag="ACG8LA_000718"
     CDS             complement(9357..10784)
                     /gene="uxaC"
                     /locus_tag="ACG8LA_000718"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008880 - glucuronate isomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006064 - glucuronate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HFQ0203043.1"
                     /translation="MFLDKNFLLENEIAKRLFHKFAKHQPIIDYHCHLDPAYLLENKQ
                     YKNLTQVWLNDKGAGDHYKWRLMRANGIEEELISGPGDDYEKFLAFVKTVEKAPGNPI
                     FEWSHLELQRYFDIDLTISEKNAPEIWRRANEKIQTDSYRPKELLEMMDVKAICTTDD
                     PTDDLWYHTELSKQDNSFKVLPTFRPDKVWSIKSSGFSNYILKLSQTAAIPIKDFNGL
                     KQALSQRVDHFHQIGCRLADHGLNTYFYEIADEKILDNLLIKALAGKTDFHLSEIAQF
                     VTGIQLHLMSEYTRYGWTMQMHLNALRNNSSILKEQIGVDVGGDSMGDQASLTQNVVA
                     LFDTAEKSGCLPKTILYSLNPTDWLPLATAMQSFQGGMIQKIQLGCAWWFNDTAEGMR
                     QQLTTMAQQSLLSNFTGMLTDSRSFLSYPRHEYFRRVLCQLLSEWVKAGRIPDDEMYL
                     SQIVENICYRNAYNYFNFFEIGSRK"
     gene            complement(10858..11937)
                     /gene="uxuA"
                     /locus_tag="ACG8LA_000719"
     CDS             complement(10858..11937)
                     /gene="uxuA"
                     /locus_tag="ACG8LA_000719"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008927 - mannonate dehydratase activity
                     [Evidence IEA];
                     GO_process: GO:0006064 - glucuronate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HFQ0203044.1"
                     /translation="MEMTFRWYGANEEKISLQEIRQIPAMKGIVGTLMDIPAGEVWPR
                     ERIKSLKDEVEANGLTLKVIESVNVHDDIKIGLPTRDQYIENYKQTIRNLAEFGIEVI
                     CYNFMPVFDWVKSDLDYRLDDGSSTLAYISKNIPTDPEEIIREVENSTNNFELPGWEP
                     HRLSQIKQLLEAYKEVDEEKLRENFAYFLKAIIPTCEEVGIKMAVHPDDPPYSIFGLP
                     RIVKNRDDLDWLCNVVDSPSNGITLCTGSIAERPDNDVYEILSEFCQRDRIPFAHVRN
                     IKYLSDNGLDFYEAPHKSEYGSLDMYKILKTMYDNGFNGYIRPDHGRMIWGETGRPGY
                     GLYDRALGAVYLNGIWEALEKGASK"
     gene            complement(11940..13571)
                     /locus_tag="ACG8LA_000720"
     CDS             complement(11940..13571)
                     /locus_tag="ACG8LA_000720"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HFQ0203045.1"
                     /translation="MVSIKNWQNSIEEFNEMQILLPCFDVKEVKQEGQQHPVWLHFGG
                     GNLYRGFHAEIAQCLADQNELETGVVVCETFDEEVVEKAYHDYNNDILEIVMSGDGEL
                     KKRLLAVTADSLYCNPKNIADYQRVVKYFEDPKLQFTTFTITEKGYSLKDSKGQFFSV
                     VKADIKSGPSNPQHTMSIVTSLLYSRFNAGELPIAMVSTDNFSQNGQRFQDSIFTIAE
                     AWQKEGYVSEKFIAYLKDKEKVTFPWSMIDRITPNPSENVKEDLLMMGLEDLDIIHTK
                     KHTNIAAFTNTEVVHYLVIEDSFPNGRPKLEKAGVIMTDRETVDKADIMKVTTSLNPL
                     HTALAVTGCLLGYQSISAEMQDDDLVGLIKGIGYLEGLPVVENPGIIDPKQFIDEVIN
                     KRLPNPYIPDTPQRIATDTSQKVAIRYGETIKKYVEKDGNAENLTFIPIAIAAWLRYL
                     LAVDDQGENFVPSPDPLLVELQDKLSVLKLGEQDPSKIHCAVQEILENKEIFGLDLYQ
                     VGVGKKTEKIFCEMLVGPQAVRKTINKYITEVGGK"
     gene            13875..14546
                     /locus_tag="ACG8LA_000721"
     CDS             13875..14546
                     /locus_tag="ACG8LA_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFQ0203046.1"
                     /translation="MTIKTSLQNQAYQSIRRQIIYADLEPGKKVSEKKLEETLSIGRT
                     PIREALIQLRQQGLVDTIPQSGNYISLIDLDSAKNARFVREHLERQIMLECCAKMNNQ
                     KKRILETIISEQEKAVSQKNARSFFHNDNLFHKACFEIAEREEVWQWLENNNTHLERF
                     RWLRVKTEGLKWEKIMEQHYQLFEALTKQDPEEANFLTSLHLHLMLNEQNIVLATHPK
                     YFKNI"
     gene            complement(14706..14897)
                     /locus_tag="ACG8LA_000722"
                     /pseudo
     CDS             complement(14706..14897)
                     /locus_tag="ACG8LA_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010818872.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
     gene            complement(15265..15606)
                     /locus_tag="ACG8LA_000723"
     CDS             complement(15265..15606)
                     /locus_tag="ACG8LA_000723"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0203047.1"
                     /translation="MSIDDCLEEQIRLFLKFLKVKVQNNYFTCYSYAHPVLNSLPFNS
                     LVQGLITNIVLLVCTPNEIFVKKIGSGISSVRLKEKEYTQKIIHIPKPEIKRFEIKDY
                     SALGLFSIGYW"
     gene            complement(15703..16155)
                     /locus_tag="ACG8LA_000724"
     CDS             complement(15703..16155)
                     /locus_tag="ACG8LA_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0203048.1"
                     /translation="MKSLEQEHMAFKQAMFKENIYLNHNYIRVSKACSPVLNMLGGGN
                     GLYHLLFVDVCWLIFLPDELVIVNEKITSKNEVFNYSLTRINYKEITKFSLEKVPFWG
                     EFCLKIKCNWKRMYFYIDGDDALTFGKTTFSSFNFQFLLKNNFYGLLK"
     gene            complement(16162..16710)
                     /locus_tag="ACG8LA_000725"
     CDS             complement(16162..16710)
                     /locus_tag="ACG8LA_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HFQ0203049.1"
                     /translation="MKRIIKIFGVLGVFLLGLSTFVSTGTSVYATEKVNTVDLEIKNK
                     LVDELTFYFDTVGFLDEHGVYHIKDFGAIRERISQDNEQGRAARVFYEHIIVPRMEKV
                     DWKRYAGCVAINSLPGGGVAWAIGTQGDFIEALKAFNFEKAADLLLKIAEKQLGKAAA
                     KELAKVNIVAGIAAAAASCALE"
     gene            complement(16755..17087)
                     /locus_tag="ACG8LA_000726"
     CDS             complement(16755..17087)
                     /locus_tag="ACG8LA_000726"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0203050.1"
                     /translation="MSEEKKEIVESLVALKDSLSKIEYVDRQEIQKLIDDTIIEIQDA
                     RCEGIKISVALSKVIEKMNRSLAFNGLKLDRQTSLIWDHLKDLYDKSKRSERTAVSIL
                     KGLWGMNS"
     gene            complement(17101..17358)
                     /locus_tag="ACG8LA_000727"
     CDS             complement(17101..17358)
                     /locus_tag="ACG8LA_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003653123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0203051.1"
                     /translation="MKKLIGYSVMCIGFVGVGLFVSTESASAAEWYNPIWYNPNIECQ
                     KGYPYGPTNLKNGKCRVNWNGVVDSVITGSMDSALHGFTGH"
     gene            complement(17553..18095)
                     /locus_tag="ACG8LA_000728"
     CDS             complement(17553..18095)
                     /locus_tag="ACG8LA_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EF0163 family protein"
                     /protein_id="HFQ0203052.1"
                     /translation="MKKGIILVFSWLCLIGLTGCHWFSSEKQKTQLRTTEETIEAVKE
                     TSGTLQSTESNSQIGSLEDETAQQMQIDEMTKNFLKDFARKWSNFTDVYKRNQAVRDY
                     MTDRCIKDNSIDVDPHVQMKTTGKLYQVTQDIENPDQYLLFGEETMNKVTQFVLLQLK
                     VDQEAQKIDAIKIYYVRSAY"
     gene            complement(18116..19207)
                     /locus_tag="ACG8LA_000729"
     CDS             complement(18116..19207)
                     /locus_tag="ACG8LA_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HFQ0203053.1"
                     /translation="MKKGCLGCLLFFILPFFLLPFFFSGELSEHGGEATGLAVAFNGE
                     YTEGLPIFSEIKGRGPITDEHAQAAVGAAVKYQLLPSVILSQLGYESAYGQSQSGRND
                     TNFFGITWFPGCPYPQGSARGIGGSEGGFYMKFPNLKACYDYYGFMVASQSNFNQCVG
                     NKDPGSCLLILGRGGYAAAGITEGSPYYRGAMSIITSYNLTEYDTFAIKHWNSLPTKK
                     TSLIAGKSKGNAKVLDRIIGRSVNNGECYGGTAWYVSQLGGPQLMGSGHMFAMLIGED
                     YNWTTYGWQVIMNPKPSDLQAGDVVNWQAGGALSPGIYGHTGIITDVSYGGQHFSSVE
                     QNAEQGRIMARYQRTYNQTKIRSLVRKVK"
     gene            complement(19215..21425)
                     /locus_tag="ACG8LA_000730"
     CDS             complement(19215..21425)
                     /locus_tag="ACG8LA_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CD3337/EF1877 family mobilome membrane protein"
                     /protein_id="HFQ0203054.1"
                     /translation="MAYIKHKEKKWCVLFFLTIGFGLLFVGGLVYAAEKQVDQSIYEI
                     GKFHIDTFSSYLSDSEFSLGKMLFGANGTDFLKMMTNMFFSLSKLIWQGLDFVIEKLY
                     EGAAMNELIHQFFTFSDTIYSKIYDPIGAGIVVLYVLYLFTLRIFRGKHYAKMVFIRF
                     LFVVIFSMVWFGYGSNVPSKGEAFTKGLNDLSVEVEGFIFSATNSLDELATKDVNGVL
                     VPTTQKEAIQKVRQLYYKAAVVDPYILLNYGTTNLEELYQAEIEPQEFLAKEASSEEL
                     SDIETKVTTAAGEDRGKKKAYRVYIQPTKAVYKAVVGSMVPLLNLSIGLPLVVIGMIR
                     FIFQMLVLCLLLVIPFSLLASFVPVFDYMLMNTLKSFLGLMFQKSFYSVIILVAFLIY
                     NIVDDLIPMNTVFGFLGNMFVKALLSILLIVKRKDLLKKLGLGAADQTINNTKNIASH
                     SLSQMKQLPGQLSTAGQNLAIKGAGLAGNVYRATNPLASAAIHGFQKFQQKRTPQESV
                     KGRQVVNPFELGGRSNQALPYSGRHVRYHGVEPEMSSTKSKTEWNSGLSNGLIPNSSM
                     NSVRPKQQVQSLAQLSKQQGNNQRKPLLNKGIAFVGQSIPLPSGKVPVPQLTAAGSLS
                     QQIRQVKNQAKNGSYPAMQQLLNQYSVPNSSVATLSGNRSVQQPGQRSSESKPSISAP
                     KSLQPAFSSLDKPTEQSEKIEKDPKTLPILDAKPGTDFTLPKGRTVQKPLSKKG"
     gene            complement(21441..23969)
                     /locus_tag="ACG8LA_000731"
     CDS             complement(21441..23969)
                     /locus_tag="ACG8LA_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFQ0203055.1"
                     /translation="MVLVKEPVKAFKKNCLLNGEDCIWAYYHVFPRTISKNTPKKTQE
                     IKEMMARLLLLLADYEDVELVMYPRTMNLRTKFDTLGKGFSPDSQAIGAYYAKETVTL
                     LEREGQVYRPSFILGIKVKEKATVESFHDVINLIWLDLAGSLARLFGLEVDDLETLFS
                     ESDPYVKEVTQLLYSFSIRPLVKKELLYLNRLQYIRGMAHKVEEQNNWEVLKDNQGTY
                     VRIPKEHKGLLQLEDELGSSYLALLPIGETPENMRNCDLFQFAQDLSFPAELRMKIHY
                     PRLKGQGGIGLKLNWLSERFKTEHKELVQNDEEPSERLLTVRGLVKHLKQRVDNGQPV
                     VDWIACFIVYGQTVEEVRQNSATVIQQLHTIIHIHRAKNDQRELFYKCLLGQPLGRQL
                     HWKHRTTVEAVGEWLFSAVSELGMESGWYIGRQDTLGDGGSRGEKTPLEELIYASNRF
                     VFLNLLAIAEGIKGALFDAPHVAVTGKTGKGKTFLVGLLFLYSSFMNVQSLFVDPKGE
                     KRKWFTKLIQDPYYQKHYPLFVEHLQKMSYVTLDATNPRNYGVLDPIVCLSRVDAKQV
                     AQDMIDELSPLGTNHLLKGAVLKGIQEVLVQKEAGQQVGLMHVVDYLEQMEQKEVREY
                     GEFLRLTVEDSILRLGFSYGENPGLDFNAKTTILEIQDLKLPNDNVRPELYTDADRKS
                     LCLMISLGRFCEMFGKRDSSKKTAIYFTEAWVFNNSNAGRSIIAAMARVGRSQMNQLV
                     LDTQFIGDLGSDKEKGNFGVVFAFDEDSEREKILNHLRLEVNEANLAEMSHMIKGQCW
                     MLDPYGRVGKLNVHSLFEEMTAALQTTEKTSHSQVEEQDTLIMQ"
     gene            complement(24021..24431)
                     /locus_tag="ACG8LA_000732"
     CDS             complement(24021..24431)
                     /locus_tag="ACG8LA_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TcpE family conjugal transfer membrane protein"
                     /protein_id="HFQ0203056.1"
                     /translation="MDWEPYDYSIVYAEPYRVQQITSNWRLPFPVALVNAATFLLVVI
                     FEYLFLRSFIGWVISFFPPAGVVFYIGLPYLCVLALAKLKPDGKKVHFYLWDWFCYMI
                     RMMNGDCVYYNWDKVSNNALEELLFVNKYVYLED"
     gene            complement(24444..24662)
                     /locus_tag="ACG8LA_000733"
     CDS             complement(24444..24662)
                     /locus_tag="ACG8LA_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TcpD family membrane protein"
                     /protein_id="HFQ0203057.1"
                     /translation="MTLKGIVDFILTQGGYFLIMVVVYLGLRNFMKSKVGNALISIAA
                     GAAVYFFLNDPTRVFDAFGKIIEKLFMD"
     gene            complement(24659..25651)
                     /locus_tag="ACG8LA_000734"
     CDS             complement(24659..25651)
                     /locus_tag="ACG8LA_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HFQ0203058.1"
                     /translation="MKKRQLRRKEKVYTEKVPKQKKIHSKKAVKWIWCLVLFLCFSGG
                     LAFFQSMKTKVQVSFLKDEIQQLQKKEVQSRSELTYTPEIESFMNRFVALYMNTFDNH
                     EQEQQRQETLKKEFYAQNFIQEPGSVSGVRKLTAASFIGLKEIETIPTASYKVTYDIR
                     SMNPESKKETSVTITQVLNLPFSISNKGCRIIAYPYFTALPKNTEKQRMITYDDTLYE
                     TVDASEAKDVEGFVEDFLDKYAKNNAKDMSYMMKEPEGLNQTAKVDQVEMKVLRYKET
                     KKPFIVKATVVFRDGDTSLLQKEQMTIVITKKTNQYYVEKLTHNWLDRKGEERK"
     gene            complement(25730..26641)
                     /locus_tag="ACG8LA_000735"
     CDS             complement(25730..26641)
                     /locus_tag="ACG8LA_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HFQ0203059.1"
                     /translation="MKKTTLAVVTTLGISLFSFQLGSSLVYADETVETPKSEIVETLP
                     GEGLPDVETELNGGTTEKPAEPEQLQSEKPEKEPVTPEPEFPESTLPTDSIEEEGVHS
                     STTTDSSIVTTPEQSGTTSSSEKNTDSSSTEQPTMSSTSEEQKEEPKQPVEKSEAIPK
                     ENKPIVPAKEVTVSVTPSGEITTNTSQGMSVPIVTSNVEELTHIPTPTTPLKVAGDQT
                     IVGVKDGIPLIQDSEGNLVKDLSIPVKKLPSGNIEIKTADGKTKVLPKTGEEIHVALS
                     VLGGVLTSIAGFVGYKRKRKGIENEGN"
     gene            complement(26660..27004)
                     /locus_tag="ACG8LA_000736"
     CDS             complement(26660..27004)
                     /locus_tag="ACG8LA_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0203060.1"
                     /translation="MWRLLFLVVCGMALFYVYRVYLYPRMERWTSWYRDPLKQRKGLK
                     RYRYELLVEFSDGRQAQYYFFANYPKYNTSELLIQLFKNNPYVGLEENGREFFYRSDN
                     ISAASMNKTRIA"
     gene            complement(27024..27302)
                     /locus_tag="ACG8LA_000737"
     CDS             complement(27024..27302)
                     /locus_tag="ACG8LA_000737"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0203061.1"
                     /translation="MSVEHFCDCYIALLRSQQLLTVERYGAEFGYVMQAERHRATRCY
                     EKEDQVIDGYEELCIRNNRYLQQRLYEQLMMDFSNLYRGYECSMIQER"
     gene            complement(27661..28161)
                     /locus_tag="ACG8LA_000738"
     CDS             complement(27661..28161)
                     /locus_tag="ACG8LA_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0203062.1"
                     /translation="MKKIMIYVGAYWSRDPTVLENPEAVHYCLRQLFYLYKERLESLI
                     RQLPYTDRRLDELLLRYPAMYKRRKNRLLPEEYPIEKHELEGRFVAYFYDDVRMRLVE
                     QRMEIENDRYYFINYCKKRKYQVTDDFYDCILQDGEVILSKIAPSFRELVPIDFLKKC
                     HLRILP"
     gene            complement(28162..28707)
                     /locus_tag="ACG8LA_000739"
     CDS             complement(28162..28707)
                     /locus_tag="ACG8LA_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0203063.1"
                     /translation="MNAYTTTEWLRLLDLKAAIEALNEKMVDLSYFRFRVPYIEQAVK
                     AGRYQEKENWQEIARLLEVRKGYEQELEELEFSRRKGRLEFIRFYRFSLPIPAILAVK
                     KGCDKMKIYENCVAALSSEKPLMEEISLVTVTWEMSRQPTEEQTYLSLEEIEIELEEI
                     GRYATCSTYCGSVISIAGAIV"
     gene            complement(28704..29960)
                     /locus_tag="ACG8LA_000740"
     CDS             complement(28704..29960)
                     /locus_tag="ACG8LA_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HFQ0203064.1"
                     /translation="MTPIELKSYRKKLSAIHNISGDKKPLSQARFAQLMGCSKDYIRK
                     MEQGKRKIPEDFEQRIKERFRLYMKSGIDLRAMIDYLRLSFFGTDYKTVIQRVLRMDL
                     TEFETRPTGLYLFDCLSVRGNIWVFWHSKRTVTENVLVQFSGQGCREYEEVMREQQTD
                     WRTWLYSIWKNQGKLEAGYTRVQCSRFDIALDELWGLETEEHFDLFELLEKQKAGLLE
                     MDFKRFQNIGGCFLDDGYFRSEGLSLYFGSRKSPLFFNFYEKRFEIANREKISELEAL
                     TKYGIYNRYELRLANEKATQAVEAFILGDSPKRLGEIGVGLINAKLIVWDRLESDARI
                     VDKRWAKLFRSMEELDFTVKPEKFSLDRSERWFLKQVAPTLKLLQEADRILGRDFVQE
                     GIDNAELNDEQQNYLEWMGTSGGKIA"
     gene            complement(30321..30632)
                     /locus_tag="ACG8LA_000741"
     CDS             complement(30321..30632)
                     /locus_tag="ACG8LA_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0203065.1"
                     /translation="MAESCYYRVATAIRMINPSLSSRTFYDWLNRIEQVTDYRFLRKE
                     RVFTGKVINQVLLTKKDIERLTRLYHYRVDLEEDLTLSIYRVFSPEKYSEITKLDHLI
                     L"
     gene            complement(30655..32130)
                     /locus_tag="ACG8LA_000742"
     CDS             complement(30655..32130)
                     /locus_tag="ACG8LA_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
                     /protein_id="HFQ0203066.1"
                     /translation="MKAHFFKYRGRRIRYFNRYLWFCYYGFFLFPFLILLGWFSWKVF
                     YPRLSTFSNWQMYLIPGISIVLYLLLVSGLILGLMHWSRLKEGYFASVYWRQLLVRML
                     IDNRFVYTKKQVSEKQTREKMRLPKVYFYQKKQELVVSFPLDGGRFHERFLKMGHLLS
                     EVFLRDLIREEREKARINYVFLSDSGRIPIDQCIAENGRIHLMKTLDWVYDQSPNMLI
                     AGAIGGGKTYLLYSLIQACLSVGTVDICDGKAADLAALGDVDVFKGHVFYKINEEMII
                     CLRNALKEMNQRYAYMKTMKDPKYEPGKNYAYYGLPPHFIFFDEWAAFYGSLDMEARN
                     RVDKLIQPLVLKGRQAGMYIILAMQRPDAEYFPSGVRDNLTFRISVGRLSPIGYLMTF
                     GEDFKNKPFYNKDQPGRGYAFPGFDVPVEFFAPFVYKDYHFIKEFEKFTEMIVYDFTV
                     KEDSQDQTMGDDNQLLQEQLERQMYLAKDPKGTSFSDAHIL"
     gene            complement(32579..33031)
                     /locus_tag="ACG8LA_000743"
     CDS             complement(32579..33031)
                     /locus_tag="ACG8LA_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0203067.1"
                     /translation="MGLKFPNNYDITEALDETCLGAVRFGALEESDRVFDNETGDYTG
                     EIRSQRAQLVFGNPDEPKIARRVKFPADVDLTGFKRRDPVKLIDPEYHVVYIPAQDGN
                     REYSDLVIYAKGLEKVEAPTNNPNMKQSQEKGLDQKQPSVDSKEKEKK"
     gene            complement(33033..33398)
                     /locus_tag="ACG8LA_000744"
     CDS             complement(33033..33398)
                     /locus_tag="ACG8LA_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0203068.1"
                     /translation="MAEKALRMKKEFLGQVFLLGSREPNPPKEINGVSGRYVQLQAEC
                     SREEQPAFFVYLTAEEDKRLRLPEKEVRISFEEAYFVFRKERVNSRETNDMGQTERRT
                     TGYQDVGVFLTGVKIGEVL"
     gene            complement(33497..37780)
                     /locus_tag="ACG8LA_000745"
     CDS             complement(33497..37780)
                     /locus_tag="ACG8LA_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010746400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VaFE repeat-containing surface-anchored protein"
                     /protein_id="HFQ0203069.1"
                     /translation="MYAKTKMNWLKALALVAFSQFCFLVGTAQAHAEETTAIQPTMEA
                     IAQVASEVTEVQPAEAGVPAGEATVEQAPVTEAPTVNSKTTLDQTIGETQHPGNSPGT
                     SQPVEETASITTPASETSTLEGEKAAEATPSVQPESSEKQAEEKKRIEETVEQPAATA
                     DKEGKNEENVEKTISSTAASQNQPTKPNKESTASIENQKKKEQNIPKTGTPTLLVTVP
                     TNRSVRVRRATNAAVLGGRKIDWGENIGVTSSPNNLNFTLNYMVRFEINGQVAFCIEP
                     GVSAAEGQVYTATALKNYLKNSNVRKKTSLISYLGYVTNKDKSDEQYIAAQFMIWEAL
                     GTKIPIKNIRVDYDRRKAEIQRLINNFGEKATFNNQTHTVKIGETLKVKNKNDFLKYV
                     KDIQKPKGVNVSIHGNEVWITVTKEAPDKAKIQLNKIKVQGAPLAYRRPGAQTIGVLH
                     PTEPNASVINLQILKQGNIRVFKEDAETGVKAQGAASLENAVYGLYQADGKKIKEITL
                     KKINGKVQAEIKDLDPGKYVLKEIKAPKGYVLSDEAIEIVVEPGKTVNATAKDQVIKG
                     TIDLVKVANKDLVDSTNPDNKPKLAGIEITLTSKTTGKVVKTVVTDNDGYATFGKNTV
                     VFDTYILSETKGKEGYKLFEPLEVTISENGQTFHYVLEDKVIEQRLKVVKVDQETGKV
                     IPLANTEFKIFDTLANRYVTMEIPNDTETTDIFKTNEKGFFLTNGTLTYGKDRYRLEE
                     IKAPVNYVLNQNPLVFSITNDTEPIKVIHFANRQARKSVKLFKYEEWNKKKTPLAGVN
                     FTLYNGKNQAIGEYTTDQNGEILVKGLVADDYYFLENAPLESFQPNTDKQAFTVAFKQ
                     NAPDDGETLVVSVRNYLIPPKLETQASNKADGEKVVDPLETIVIKDSVSYTNLFVGKE
                     YTISGVLMNKATNAPILQDGKEITSTLAFIADKVNGTKDLEFVVNASVLKGQTIVVFE
                     KLFRDGIEVAAHADINDEAQSVKVNNPTVHTTAVFEDGLTVADPTGLFTLNDTVEITE
                     ILPGKAYLVKGILMDKATGEPLLVHGNTVETSVGFIAKAENETVIVPFTFDLTGINGR
                     EIVVFESLFRNDEELANHKDINDKGQTVRVTNPSVRTTATHKPTGLKEVNPLTKVTIT
                     DAVKYHDLVVGKTYTVNGVLMDKVTEKPVLVDGKEVTSTLTFVAETTDGTVNLDFILD
                     ARALRGKEVVVFEDLFREGVLLASHADITDNDQTIKISNPTITTKATNKNGGKEILAL
                     PNQTVLEWVKVDGLAIGQIYRLIVQGYLTPDGTPFEGTHAEKVFAADKEMMEFLFEFL
                     VDGRNLAGKGLSFAEWLQAKTEDEKETFEEVAKHNVDLTNKDQTVQIVEAPKPPQPVK
                     PEQRVKPATVVPMLPKTGEQTSSILMVLGLVVLVIALGITLYKVRKAKD"
     gene            complement(37927..38166)
                     /locus_tag="ACG8LA_000746"
     CDS             complement(37927..38166)
                     /locus_tag="ACG8LA_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0203070.1"
                     /translation="MIDISLPEDLKPDPVTIGNSVMIFDSLDEAMSYGWKEIKDEGSN
                     WYGMRFGDGEVAKKAGIPIGKWTVDFHEAGSFFVL"
     gene            complement(38256..38498)
                     /locus_tag="ACG8LA_000747"
                     /pseudo
     CDS             complement(38256..38498)
                     /locus_tag="ACG8LA_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010708076.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(38611..38862)
                     /locus_tag="ACG8LA_000748"
     CDS             complement(38611..38862)
                     /locus_tag="ACG8LA_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0203071.1"
                     /translation="MRKVLVFNTRGQSFLGIEGTRVTVDGWCDCFEVGKHVELMAFTE
                     LKDKNNVEFFESDIGWDDHEEVYGKFILRKGNSYTNGEA"
     gene            complement(39858..40769)
                     /locus_tag="ACG8LA_000749"
     CDS             complement(39858..40769)
                     /locus_tag="ACG8LA_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0203072.1"
                     /translation="MVDNSSGRVLKSLRKEKKLSQKKLADLAGISQSTLVKYEKGSRK
                     IPKDVDNTLSKILNIETLIKDEEDKIEILIGKLIAYRDMNKLLNKELADNIGISEVLL
                     SYVLNRKRNPSKEMQKKIDIFLLSNEKEILKEINRDSEIFSLSKDDKIVMGKRIREVR
                     KNREETLEKFGKNFTIYTGKNVISRWEKGINIPDIEKLMNIAYLGKVTVPYLMYGEDY
                     KNILPKDERVSDFKKINSFSMGLRMRKIRKDYYLEREEFGKLFSPSISKWSIDRYENG
                     RDIPNTNRIIQYAYIGNLSLEFLIYGI"
     gene            complement(40965..42800)
                     /gene="lepA"
                     /locus_tag="ACG8LA_000750"
     CDS             complement(40965..42800)
                     /gene="lepA"
                     /locus_tag="ACG8LA_000750"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation elongation factor 4"
                     /protein_id="HFQ0203073.1"
                     /translation="MDIKKMKERQEQIRNFSIIAHIDHGKSTLADRILEMTHTVTSRE
                     MQDQLLDSMDLERERGITIKLNAVELNYTAKNGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAVLVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRQEIEDVI
                     GIDASEAVLASAKSGIGIEDILEQIVEYVPAPSGDLDAPLKALIFDSIYDSYRGVVLN
                     VRITDGMVKPGDKIKLMSNGKTFDVTEVGVFSPKAVARDFLMVGDVGYITASIKTVQD
                     TRVGDTVTLADNPAAEALPGYRKMNPMVYCGLYPIDTSRYNDLREALEKLQLNDAALQ
                     FEPETSQALGFGFRCGFLGLLHMDVVQERLEREFNLELITTAPSVIYHVNKTDGTTAT
                     VDNPADFPEPVTIQDVEEPFVKAQIMVPNDFVGAVMELSQRKRGEFITMDYLDDYRVN
                     VVYNIPLSEIVFDFFDKLKSSTKGYASLDYEMSGYQKSKLVKMDILLNGEKVDALSFI
                     VHRDFAYERGKAIVEKLKKLIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKEGKKRMKQIGSVEVPQEAFMAVLKMDEQDSVK"
     gene            42947..44167
                     /locus_tag="ACG8LA_000751"
     CDS             42947..44167
                     /locus_tag="ACG8LA_000751"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFQ0203074.1"
                     /translation="MDQKDFRENLELKPVTQEHIDQFNELLSYVFQVTEADIEESGFE
                     NKRAFIRSKKPILEVSKVFGWFHENKLISQIAIYPCEVNIHGARYKMGGVTGVGTYPE
                     YANHGLMQDLIIVALDNMRKNKQWISYLYPYSIPYYRRKGWEIMSDKLSFKIRDTQLP
                     KQIPVSGMVERLPVDHPDVFSVYDKFAQQNHGALFRSDFHWEEYWRFENEDERTAAVY
                     YDSNHEPRGVLFYWVAEEIFHVKEMFYLDQEARNGLWNFISAHFSMIYWVHGDIYKNE
                     PLAFLIEDSQIKEQIEPYFMARIVDVKEFLQRFPFVGTADAFHFIIEDPVAPWNNGVF
                     ALTWDEQGQVRVLNEPIGKSVRLDIQTLTCLMMNYRRASYLARIERLETDEETLKSLE
                     RIIPNMEAYFSDYF"
     gene            44187..44681
                     /locus_tag="ACG8LA_000752"
     CDS             44187..44681
                     /locus_tag="ACG8LA_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside 2-deoxyribosyltransferase"
                     /protein_id="HFQ0203075.1"
                     /translation="MKIYFAAPMFAKSDLLYNQQLVKEIRELSSELSIYLPQENEAIN
                     DKTAYADSRMIALADTEKVLASDLMIALLDGLTIDAGVASEIGVAYAKGIPVIGLYTD
                     TRQQGGTHPKKIAALQETAENQFHYLNLYTIGLIKLNGKVVSSEIELLSEVKRFLDGG
                     TFSD"
     gene            44659..45345
                     /locus_tag="ACG8LA_000753"
     CDS             44659..45345
                     /locus_tag="ACG8LA_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0203076.1"
                     /translation="MEGLSVIKEIKKVQIALLAFGVFVVCYNFYEFITQKYSTSQGIT
                     FIVESLLGIALIFMPQVILKVFKLKIPAAIVLFYWFFLFISVFLGTGMHLISIISFWD
                     KILHAVSPMVLTALGYGLIGYLMKDAEISKTSPWLFLLFGFAFAGLCGVFWEFWEFLC
                     DQFLGMNLQRFAASDGTLFVGRAALMDTMGDLLTNTIGAALMGLFAWSQSKKDERYFE
                     SYKLEKVKNT"
     gene            complement(45496..48105)
                     /gene="clpB"
                     /locus_tag="ACG8LA_000754"
     CDS             complement(45496..48105)
                     /gene="clpB"
                     /locus_tag="ACG8LA_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_process: GO:0009408 - response to heat [Evidence IEA];
                     GO_process: GO:0042026 - protein refolding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HFQ0203077.1"
                     /translation="MNIEKMTTTLQEAIAEAQQIAVTRKHQDIDIAHVWKIFLQSNHF
                     GRNFYTDAGLDVESFEHEIDRLLDEYPVVSGGNVQYGQNLSQNFFRLLNEADQIRESF
                     GDEFLSTEVVILALMKLKNYPLTVYLNKNGLSEKELRKNIEEMRGGERVTSQNQEEQY
                     KALEKYGVDLVQQVKSGKMDPIIGRDEEIRDVIRILSRKTKNNPVLIGEPGVGKTAIV
                     EGLAQRIVRKDVPENLKDKTIFSLDMGALIAGAKFRGEFEERLKAVLKEVKKSDGRIL
                     LFIDEIHNIVGAGKTEGSMDAGNLLKPMLARGELHLIGATTLDEYRQYMEKDKALERR
                     FQKVLVKEPTVEDTISILRGLKERFEIHHGVNIHDNALVAAATLSDRYITDRFLPDKA
                     IDLIDEASATIRVEMNSMPTELDQVTRRLMQLEIEEAALKKESDDASKKRLKNLQEEL
                     AELREEANAMKMQWETEKEEVNSVSAKRAEIDKAKHELEDAENNYDLERAAVLRHGTI
                     PQLEKELKELEAKAKDSEIKMVQESVTENEIAQVVGRLTGIPVTKLVEGEREKLIKLN
                     ETLHKRVIGQDEAVDAVSDAVIRSRAGLQDPNRPLGSFLFLGPTGVGKTELAKALAEN
                     LFDSEDHMVRIDMSEYMEKHAVSRLVGAPPGYVGYEEGGQLTEAVRRNPYTIVLLDEI
                     EKAHPDVFNILLQVLDDGRLTDSKGRVVDFKNTVLIMTSNIGSQLLLEGVTADGTIPE
                     AVAEQVNTLLRGNFKPEFLNRIDDTILFTPLSLDNVKGIVDKMVAQLAQRLEHQEILL
                     TISDEAKTWIAENAYEPAYGARPLKRFITKEVETPLAKEIVAGHVMPKSKVTITLLDG
                     QLHFKTEELEEIV"
     gene            complement(48356..49402)
                     /locus_tag="ACG8LA_000755"
     CDS             complement(48356..49402)
                     /locus_tag="ACG8LA_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbhN family protein"
                     /protein_id="HFQ0203078.1"
                     /translation="MSSKGTKTKIILNLLLLIVIFAIIYYLINQSFADIFAELLSTSV
                     VVLAAAVILGTVYQIAEGRSIKEIAEPFAPNFTTKDGFLTSSYIAFYRIVSFGTGTLI
                     SEIYFYNKKGMKLSQGAGVTALHMIMYKLAVITYALAGLVIQFSLFYSNGPSMIWFII
                     AGILLTIVIVAFLLAMSVSLNVQIFFVSLSNKLFKSERLRKWVDTCNQQIYSLRETVQ
                     TIIQDRTALLRIYLWNMLKLVFWYVLPYLILIENHPKIDFLLTISFISFAVVLSGVIP
                     TPAGIGSFEFVYLLLFRPVVGTVDAVSSLLLYRFSSFILPFLYGFVYVIAERRRVIKE
                     EIIEVKKENKENQG"
     gene            complement(49413..49685)
                     /locus_tag="ACG8LA_000756"
     CDS             complement(49413..49685)
                     /locus_tag="ACG8LA_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HFQ0203079.1"
                     /translation="MDVLLHNPLWFYLFIVNFYLFCLMGYDKHQARTSGWRVPENNLI
                     FVSLLGGGLGGLISRKVFHHKTRKKKFTIGFAAGVLVDLILIYFFH"
     gene            complement(49720..50628)
                     /locus_tag="ACG8LA_000757"
     CDS             complement(49720..50628)
                     /locus_tag="ACG8LA_000757"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HFQ0203080.1"
                     /translation="MEKLLVFYNKSSGKDEGEKLARWFQDYVKEKQPELYVELAETGP
                     SIDDAELVKKAEAIEADTLVIIGGDGTIHHIVQAFQKTLSQYHVGLLPGGTVNNLARV
                     LEIPLKKEEAADVILEGNVRKIDYGQVNDEVIISTLTIGILADTAVWISQEEKQRYGS
                     WIFIKKFFKLLLKKKKYHLDLETDEEHWKGKSQLLTVTMSNSVGGFTNFDDSATLDDG
                     KFHVTIVPSLDIFRFIFYLPRIMRGKFYTIPGITYFTAKRMKIQAQEKSVGTRTDGDT
                     TDDLPVELSVVSKGLTVYSPKKEEKA"
     gene            complement(50760..51992)
                     /gene="pepT"
                     /locus_tag="ACG8LA_000758"
     CDS             complement(50760..51992)
                     /gene="pepT"
                     /locus_tag="ACG8LA_000758"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0045148 - tripeptide aminopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HFQ0203081.1"
                     /translation="MYENLLPRFLRYVKTETRSDATSKTTPSTQTQVAFAQELKKELE
                     ELGLADVFYNEDNGFVMGTLPSNVDHEVRSIGFISHMDTADFNAVGVNPQIIENYDGE
                     STIVLDAEERYTLNTKDFPNLKNYEGHTLITTDGSTLLGADDKSGIAEIMTAMEILIN
                     NPSIPHGTIKVAFGPDEEIGVGADKFDVEQFDVDFAYTVDGGPLGELQYETFSAAQAN
                     ITIQGKNVHPGTAKDTMINALQLAIDFHNQLPADEVPEKTEGYEGFFHLMALDGNPEE
                     ASMSYIIRDHDREKFEARKAQITHIQEELNQRFDQERIKVDMYDQYYNMKEIIEKDMS
                     IVELAKQAMIELGISPVIEPVRGGTDGSKISYMGIPTPNLFAGGENMHGRFEFVSLQV
                     MEKATDVIVKIAELNTKS"
     gene            complement(52007..53128)
                     /locus_tag="ACG8LA_000759"
     CDS             complement(52007..53128)
                     /locus_tag="ACG8LA_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0051540 - metal cluster binding [Evidence
                     IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HFQ0203082.1"
                     /translation="MTISGRTFIQKFESYCPQWLAEEGDPVGLHIGTLDKPIQRVMMT
                     LDVRPEVVEEAIKKKIDLLIAKHPPIFRPVKRLVTDQPQEKMYADLLKHDIAVYAAHT
                     NMDIIWDGLNDWFCELLGIEVESYLVKTHEIHYKKLAVYVPVDHAQKMREVLAAAGAG
                     TQGDYTGTSFTSIGHGRFTPEAGAQPAIGKVGKTEQVQEAKVEVILPETIEKQVIQAM
                     RSAHPYEEPAYDLFAIDEPVEMFGLGRVGELPQEISIEAFVEQVKEAFQLDGLRIVQP
                     KNAKSSVKRIAICGGSGEKFYPQAIAQRADVYITGDIYYHTAHDMQSAGLIAIDPGHY
                     IESLCKQRFIEKFESWKQEENWDINFFVSETNTNPFQFN"
     gene            complement(53125..53826)
                     /locus_tag="ACG8LA_000760"
     CDS             complement(53125..53826)
                     /locus_tag="ACG8LA_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine(22)-N(1))-methyltransferase TrmK"
                     /protein_id="HFQ0203083.1"
                     /translation="MNHLDLSQRLAAVGDFVPESARLADIGSDHAYLPVALILRGKIE
                     YAVAGEVVQGPYESARKQVKKDGLEDRITVRLANGLDAIQPQDGITAVTIAGMGGSLI
                     RDILEAGKLNQRLSGQERLILQPNIGERTLRSWLQENQYKIQSEKILEENKKIYEIIV
                     AEKEQKPVTYNEMELMFGPFLLEEKSEIFKSKWTRELQQRKAIREQLKQAANQEARQK
                     QIEQEIQMIEEVLKP"
BASE COUNT        16179 a        11175 c         8024 g        18513 t
ORIGIN      
        1 aaaaccaccg gtggcaaacc ggtggcaaat ccatgtaaac atggtttatt ttttacactg
       61 ttttcaaaca aacccttgct atttcttcgg ttcgtcctcg tccattttcg ataccgacag
      121 ctagcttata acccaaggta tatcaacata aaaaaataaa aataggctat gacagcagcg
      181 tgacagcaaa aaagatggaa agttaaatat caaacctcgt aatttcattt gcgagtgctt
      241 gatttgtttc tggatataag tgtccatatt tgtccaaagt agttttaata gaggcatgac
      301 ctagacgctt agatattgca tagatatttt tattatgttc aattaaaaag gcaacatgcg
      361 agtgtcttaa tccatgcata tgaattggtt ttactcctgc aatttcagct agttttttta
      421 ttctgcttaa aatagttctt ggagatggcg gtaatccatc aaaagaaaaa accaattcta
      481 tatttttccc aattgattgt tgagtttttt tccatgtttt taaatcttca acggtttgtc
      541 tgtctaacga aattatccga atacttgatg tattttttgt ttcagcaaat tcataatctt
      601 gtcttgtacg gatgtaaatt gacttattta cgctacatct gccatttatt aagtcaaagt
      661 ctttccattg taacgctaag agctcctcac tccttacacc tgtaacaaaa ataaaacgca
      721 tcaaacgttt ataaaattct tcataaaaat ccccgtgata aacactatta tatactttct
      781 taaattcatc aactgtccaa aattctactt gaggacgctg agtttttatt ttacctatag
      841 tatctacagg attttcttca ataatttcaa gtacaattgc ccttttaaaa actactctca
      901 acttattgaa tatctgttta atataatttg gtgataatgg ttgctcaatg ccctttttta
      961 caacatggat tttcgataaa aactgttgaa attcctgtat atgaattggt cgaatcttta
     1021 caacctgcat ttctccaaaa aaatccaatg cacgttgtaa aatatgatct gttttcatat
     1081 atgttttttc tacagttccc aacttatacc aaggaaaaaa atactctcga taaaaatcat
     1141 gaaacgttat tccttgcaga taaattcctt gtgaatcaga aaaactttgt tttaactctt
     1201 cgagtcccct tctagcttct ccttgagttt tgaagcctct tctggtcact tgaattcttt
     1261 ttccaaagcg atcttgtcct aaagttgcag aaaaaaacca agtgcctctt tttctgtctt
     1321 tataaacatt cgcaattttc ctcattttac tattcctccc aagaaatatg gagaacttct
     1381 tctaaaattg aaataggaat tctttttatt tttgaattac gataaaaaaa gtatcctttc
     1441 tcaactaaaa gttctttaca ttccttgaag attttattag catagtactg agaaaaacct
     1501 agattaatca aatcttttcg agtagctgtt ttcattatag caccttcctt actttttttc
     1561 atttatttct atcagctgct tttgtcaaaa gcacatagga atttcacctc tccccaagtt
     1621 tacggcgagc cttacggaag tatcattatc ccaactttaa atcatcgctt tttattgact
     1681 ataaaaatta ttttagaata tttatcgctc cttctttaca gcaagaaatc atggcgcaac
     1741 taaaatatgc tccttaaagt gttaacgtac tgatagaatc tatttaattt tcaatgaaca
     1801 ataggttttc tacctaaaag aatctactaa ttccttaact attagaagat tcttttaaac
     1861 agaaaaagtg gaaaggggat ttttttaatt agttaatttt aaattttaag atcgcttcta
     1921 ttaatttaat ttctagctga cttatcatat attcatctac ataggtaacg aattgaccta
     1981 cctcgttaaa tccatttgtc aaacataact tagccatata agaatgataa tgtttgagta
     2041 tcatcttgat cgaaattgga tctccttcta gagcagataa gataatggat agtggaacta
     2101 ataggtactg ccgcttttta gatttatcta ccataggtca taccccattt tcaattgttc
     2161 aactgccttc tttcgttgat accagatacc acttgtgctc atattgagaa ttttaccgat
     2221 ttcagcatca ttaaaacctg caaaataata aagtaggata atctttcttc ttatctccga
     2281 taactgatca attgctgctg ataacttttg atctgaaatt aatatttcca ttccaaataa
     2341 gaaatagaca tcttgttcat caaaatgagt ttgggaatac ctgccttcat ttgaatctgc
     2401 caatggttcc tcattatcct ttatgttagc gtttcgtttt cgaatagact tagcttcgtt
     2461 tcgtaatact tttttacagt aggcatcaaa ttggtgttgt atagatatgt cattgtaatg
     2521 ttgttgcatg ataatatgct cctttttccc cctttccact aatacaacaa tcagaaagcc
     2581 cctttttttc gaaaaaacta gaaaaaaaac ataaaaatat ttatcattct ttaaacagaa
     2641 aatctttcta taaaaaacaa aaaaaaacga ttaggctagg ctaatcgttt tttgaacatt
     2701 cttaaaaaat ccaaattatt ttttataact gaaattgggt attgatgacc atcgtttctg
     2761 tagatagtaa gcaatcattt taggttttct atctctagta aagattcctt tcttatttcc
     2821 ttgcactctt aaaatccctt gacttgttgc aaaatctgca aaattccaca cttgttcacc
     2881 aacaaaattt tcacatgtat ctattacttc gtgatttgct tcgtaataag ccacttgata
     2941 ctcttctgta aacattgttg gtactgtatc atgaaatcca gctactgtat ctgctccata
     3001 ttctgtaaac attattggcg tatcaggaca tctttccatc catccatcta gctctttttt
     3061 caacagatat tttgcatgtg ccagatcccc tcccgaaaca taccaaccat aataacgatt
     3121 taaacataaa acatcgacaa tatctcctac cttacaaaca tctggcgttg attttagata
     3181 agtaacgatt gttacaggtc ttttctgcgg atcaagttct ttagttaatt caactaaagg
     3241 ttcaaaatat tctttagcac cttcggaatc cgaatctggt tcatttgcaa tagaccacat
     3301 tacaacactt gggtggttct tgtcgcgttc tatcaattcc ttgatcaccg ttttatgaga
     3361 attttctgtt cgtatctctt tccacgtatt atgtttttcc acattatcat ctaataaagt
     3421 ggccatgaaa tttaaatgta accctactgc aggtacttca tcaataacta caataccttc
     3481 tcgatctgct aatcgcataa tttcttctga gtaaggataa tgtgatgttc taaaagaatt
     3541 agcacctatc catttcatta aattaaaatc tttaatattt acagcctcat tcaaaccacg
     3601 tccattaaca tacgaatcct catgcttacc aaatccttta aaataaaaag gtttattatt
     3661 aatcaaaaat ttgccattgg taacctgaac actgcgaata ccaaattctt ctgtataggt
     3721 atcgatcact ttattatcat caattaaact aattttcata ctatataaat aagcgtctag
     3781 aggttcccaa aaaattggat tcttaagctg aatcattcct ttctttcctt cagcttcagc
     3841 tacaagttga gcctcttcgt catatatcgc tattaagatt tttccggtcc attctgtatc
     3901 gatattgaat tctacacttg catccaaatc agttattctt gtattaatag taatatcact
     3961 tatatagtct ttcggagttg tatataactt aacaggtcta tgaatacctg cataattgaa
     4021 gaaatcaaaa ttaactaagt tttccttttt tatatcccca ttttcctgta ctgtttcctt
     4081 cataatcccc acaggtaaag tactatcgtc aataatattg tttacagcaa ctgtaattcg
     4141 attattcccg tcttttacaa accgattaat ttcagactca aatggtgtaa acccaccttt
     4201 gtgttgagta ataaactttc cattcaaaaa aacttttgct tcatgtgttg cagatccaaa
     4261 acgaagaact aatctttctt ctaataatct tttaggaaga gtcacttctt tttcatacca
     4321 cacccatcca acatgatttc taatgttctc tgtttcaaat aaatcattat aagaagaggg
     4381 aactgaaatc ggataactct ctttttcatt tattggttct aaagcaagtt cttcctgtaa
     4441 gtcatcattt gtatctaatt taaatctcca gagaccgctt aagtcaatta cttgcctcgt
     4501 ctctgtcata atgggataca acatataaac cactcctatc taaatattaa ataaatgtat
     4561 cctttaaacc acaataagca tctattggac ttactccctt aaattcagaa agacccatta
     4621 gtttgtccac caatatttct aaagtttctt gttttccatc ataagtatta atataagtct
     4681 ttacttgagg tacatcagcc aaatgaaacg gacactgtac agatacaaaa attgttggaa
     4741 tttcatgaat gtaaaacggt atatccggag ttcctttact tgctggccag acaattcgtt
     4801 gaactgtgcc tggattaaca ttagctatat taatgatcaa gtcatatttt ttagttaaat
     4861 ttttaattgg tctcttagca gcatatattc cagctatatt tttaattttt tcttcttgcg
     4921 ataatccttt caattcttct tcaggtgaaa tgtatttttc aacttcaaat ccttttgctg
     4981 acaaaatctg tttcaataaa tcaatggctt gaggtctatt tccagcaact acttcaccaa
     5041 acccaccttt taccccatgt acatctacta gtaaaatcct tttatatttt tctggtacaa
     5101 taggccaaat atcttgttta tctttaacta atgtaattgc ttggtcagcc acctctttaa
     5161 aaattgattt attttcaatt aaaccaattt tttccagagc ttcttgctta ggtaataaaa
     5221 tttgttcttt tgcttttttg tgtaatccca atttagcttt taaccctaaa attcttttta
     5281 aggcatctaa taaccgatca tcagtgataa ttcctttacg atagccttcc atcatataat
     5341 taaagtcttc atctggatca ttaaaaaata gaaatagatc acatccagct gcaatagaag
     5401 tgggcaataa ttctgatcgt ttcattgccc cagtcattcc taacatatga ctagcatcag
     5461 taactactaa tccattaaat ccgagttttc ctctaagtaa gtcagtgatt aattcttttg
     5521 ataaagttgc aggaagtaaa tcttcatctt tcagatcagg attaaaatgt tttgaataag
     5581 ctggcatatg gatatgacct gccataattg aaggtaatcc agcttctatt aagcctgagt
     5641 atacttttcc aaaagaatta tcccattctt ccgtacctaa actattaata ctaaaagata
     5701 gatgctgatc tcgttcgtca ataccgtcac cagggaaatg tttagctgca ggcaaaattc
     5761 cactctcctg aatacctttc atataagcta aactaagttc taaaacttta tcagggtttt
     5821 gtccaaaaga tcgactagaa atgataggat ttctccaatt tctattaata tctacaatag
     5881 gagcaaaact ccagttacat ccaatagccg atgcttcaat cccagaaact ctccctaatt
     5941 cataagcata tttcgcatca tttgttgcac caatttttac ttctacacca acttcagtac
     6001 catctgtaca agctccgtta ccacctgctt ccgtattagc agcaattaat agaggaattt
     6061 tactttctgt ttgtaagata tagttttgat catatacctc atcagcagtt cctggattat
     6121 atcgtacagc tccaatatgg tactgattga ccatattact caagtaattt ttatcacgac
     6181 tagatcccat attaacaaac aattgaccta ttttttcttc caaagtcata gaatcaatcg
     6241 tctcttcaat ccaagaaata gcatcttcat ctaaattata tggttttttt cgtaaatcta
     6301 cttttatagt cattttcttt ctcctctact tattagtaag atttttccaa aaagtatcta
     6361 tatatttttg ttcaatatct acataatctc ccgataaaca tttaaataaa acatcagttc
     6421 ttaagttttc ccatgattct ttttctttat tgaccaaaat aggataaaag aaaactttat
     6481 ttttatttgc agcttctaga tcaccaggag aatcaccaat cattaatatc ttatccaaat
     6541 cacaaccatt ttcaattaca cttcgaataa tatcttcttt ttttccttta tcttgacaac
     6601 acagttcatc aactaatgat aataattcat gtctttccca ttcttcttga acagcttcct
     6661 tattagctga gcttacaata attatcttcc catatttttt cagagctttt atagtatctc
     6721 tagcacttaa aaagggttta tctaatcctt ttgcttgact aatctgttga ttgacttctt
     6781 ccgaccattt taaagctttt aataaatcct ctgactgaga atattctatt tccctcttca
     6841 aagatggatt agacaattct tttgttagag atacccagtg ctttaatcga ttaatcgatg
     6901 ttacatcatt tttttctaat gttttaacta aacctaaaaa tctgtttatt ccacgagtct
     6961 ctgaatataa attaatatta ttccaatcct gtaggaattt ttctctatga tgaacatcaa
     7021 aaatctctgc agcaattggt ccgaaaaaga gattgtgttt ataagtcatc gtatccataa
     7081 cacagccatc tgaatcaata caaaatatcc aattattcat atttctctcc tatttatgtt
     7141 tttgttttaa aagctcgcaa ttttctaaga ctttatcttt agataatgga taaaggaaaa
     7201 ataaaattaa tcctacaatc agaaaacaaa ttgatggaat taatgttgaa gcgttatata
     7261 acttttctaa aacatctccc gtttgtacat ttgctaaaga gtcatagcct ataatagaaa
     7321 gagtccaacc tccgacgcct ccagctagag cttgacctat ttttctagca aaagaatata
     7381 ccgcatatac ggtcccatct tctctttgat cagactttac ttcttgatca tcaataacat
     7441 cagtaatatt tgcccaaata acagtattaa acacacccaa acccatatag ccaaccgaac
     7501 taagaattaa gaatacatac atattactag cttttatcaa aaataagatc aaatatacta
     7561 ttgctgaaaa gaacattcct actgatgcca gttctttttt tccatatttt ttacttaaaa
     7621 acaaagttaa aggcgaaaca actattaaaa ccaaaatagg attgataaaa ttcattaaaa
     7681 ctattccctg tgcatcatta tagtaatcag gaaatacata attattcata ctcataatta
     7741 ataattgagc aaggagtaag aaaatagccg caccaattat agaaagtaat gccctatttt
     7801 taactaaccc ttttaaagat tttaacaatg aaactttgta ttgagattgg tcaattctta
     7861 ctcgttcagt agttagttta taacatatta aataacaaat aagtgcacat atcgaaaata
     7921 ttcccgcaac aattgtaaaa gttgatccac cacgaactat ttgagcgcct gaatcatctc
     7981 ttgtataaat aaataatggt gttaatacac caatgaccaa acttgctaaa gtagctccaa
     8041 catttcggaa tgtcgatagc attgttcttt cttctgtaat agaagtaata gctgatgcca
     8101 ttgatccata aggaatattt atagatgtgt aaaaaatact cccccataat atatacgtaa
     8161 catacatgta tactacctta acgctcatag aagctgaaat catagaagtt tgatacatta
     8221 aaaaacttgc taaagcgact ggaccactca ttcttaaaat ccacggttta aacttaccct
     8281 gcttagttgc tttcgatcta tcaacaatac gccccatagt tacatcagta actgcatcga
     8341 taaatcttgc tactaaaaat aatgttccaa cggcagctcc gcttatcccc aatacttttg
     8401 tataaaagat cattaaaaaa gaactagcaa aaatgaaagt aaaatcgttt ccaaaatctc
     8461 caaacatata tcctattttg tctcttatac caaattttct ttccatacaa ttctctccct
     8521 tctgttgtta agcgttttca ttctgatgaa agtacgtact atactctgaa gcgtaaagag
     8581 tcagtattta ttttttacat ttcagagtat tatttgtttt ttctcctaat aattctttat
     8641 ctcataaaac ttatctatat atttactagc tactcgactt acttcttcaa aatcaccttt
     8701 ttcaacagaa gccaataaat tcccacctac accaactgca acaactccta cttcaaacca
     8761 atcttctaag ttctctatac ttactccgcc agtaggcatt atatttacgt gtggtaatgg
     8821 agcttgatag gcttttacaa tggatggacc aaaagcagaa cctgggaata gtttaatgat
     8881 atctacgcca gcagtaagtg cctcctttat ctcagtaatt gtcatacaac ctggtaaata
     8941 aggaatttga tataaattac aaatctcagc tgtttgtcga tcaaaagatg gactaacgat
     9001 atattctgcc ccagccataa ttgcgatacg agcagtaaac gcatctaaaa ccgtaccggc
     9061 tccgattatt acatcttttt gatcagcata ttttttagca atttctttga ttatttcttc
     9121 agcattagga actgtaaaag ttagttcaat ccctttaatt ccacccgcaa taattgaatt
     9181 tattgcttta atggcctcat ccttattttt cccacgtaca accgcaatga ctccagccgc
     9241 ttctaactta cttaaaattt ctactttttt catatctatc tccttccttt atggatacat
     9301 actttgtcta gctgtactaa cttacaaaga ataaatttaa gcttttattt caagtattat
     9361 tttctacttc cgatttcaaa aaaattaaaa taattatacg cattacgata acaaatattc
     9421 tccactatct gactaagata catttcatca tctggaattc ggcctgcttt aacccactcg
     9481 cttagtaatt gacataatac tcgacgaaaa tactcatggc gaggatagct tagaaaactt
     9541 cgagaatcag tcaacatacc tgtaaaattc gacaacaaac tttgttgtgc catcgtagtc
     9601 aactgttgac gcattccttc agctgtatca ttgaaccacc aagcacatcc caattggatt
     9661 ttttgaatca tacccccttg gaagctttgc attgctgttg ctagtggaag ccaatcagtt
     9721 ggatttaatg aatataaaat tgtttttggt aagcacccac tcttttcagc ggtatcgaac
     9781 aatgctacaa cattttgtgt caaactagct tgatccccca tcgaatcacc accgacatct
     9841 actccaattt gttcctttaa tatacttgaa ttatttctta aagcatttaa atgcatttgc
     9901 atcgtccaac catatcttgt atactcagac atcaaatgta attgaatacc tgtaacaaat
     9961 tgtgcaattt ctgataaatg gaaatccgtt tttcctgcta aagcttttat taacagattg
    10021 tcgagtattt tttcatctgc tatttcataa aaataagtat tcaaaccgtg atctgctaat
    10081 cgacagccaa tttgatgaaa atgatccact cgttggctca atgcttgctt caacccatta
    10141 aagtctttga ttggtatagc cgctgtttga ctaagtttta aaatatagtt cgaaaagcct
    10201 gatgatttga tactccagac cttatctgga cggaaagtag gtaatacctt gaaagaatta
    10261 tcctgtttag aaagctcagt atgataccac aagtcatctg taggatcatc cgttgtacag
    10321 atggctttca catccatcat ctccaacaat tctttcgggc gataggaatc cgtttgaatt
    10381 ttttcgttag cacgtcgcca aatttctggt gcattcttct cagaaattgt caaatcaata
    10441 tcaaagtaac gttgtaattc caaatgagac cattcaaaaa taggattacc tggcgccttc
    10501 tccactgttt ttacaaaagc taaaaatttt tcataatcat cacctggacc actgatcaac
    10561 tcttcttcta taccattagc tcgcatcaat cgccatttat aatgatctcc agctccttta
    10621 tcatttaacc atacctgagt caaattcttg tattgcttat tttctagcaa atatgctggg
    10681 tctaaatgac aatgatagtc gataattggt tggtgttttg caaatttatg aaaaagtctt
    10741 ttagctattt cattctctaa taaaaagttc ttatctaaaa acatatttaa acactccttt
    10801 ccttccgtta gtttttagaa gagaaaattt ttcctctaaa taaactccct tatataatta
    10861 tttactcgcc cccttttcaa gcgcttccca aataccattt aaataaactg cacctagagc
    10921 tcggtcatat aatccataac caggtctacc ggtttctccc caaatcatcc gaccatgatc
    10981 tggacgaata tagccattaa atccattatc gtacattgtt tttaatatct tatacatatc
    11041 tagagaacca tattctgatt tatgcggcgc ttcgtaaaaa tcgagtccat tgtcacttaa
    11101 atatttgata ttacgaacat gtgcaaaagg aatccgatcc cgttgacaaa attcagatag
    11161 aatttcatag acatcattat ctggtcgttc tgcaatactt ccagtacata atgtaatacc
    11221 attagaagga gaatccacta cattacacaa ccaatctaaa tcgtcacgat ttttaacaat
    11281 acgaggtaat ccgaaaatgg aatatggtgg atcatctggg tgaactgcca ttttaatccc
    11341 aacttcttca catgtcggga taattgcttt gagaaaatat gcaaagttct ctcgtaattt
    11401 ctcttcatca acttctttat aggcttctaa taattgctta atttgtgata accgatgagg
    11461 ttcccaaccc ggcaattcaa aattattagt agaattttct acttctctaa taatttcctc
    11521 cggatcagta gggatatttt ttgaaatata ggctaacgta gaagacccat catctaaacg
    11581 ataatccaaa tccgatttta cccaatcaaa tactggcata aaattataac agataacctc
    11641 aatcccaaat tctgccaaat tgcgaatcgt ctgtttataa ttctcaatgt attgatctcg
    11701 tgttggtaaa ccaattttga tatcatcatg aacattaaca ctctcaataa ctttcaaggt
    11761 aagtccattg gcttcgactt catcttttaa agatttaatt cgttctctcg gccaaacctc
    11821 tccggctggt atatccatta atgttccaac aattcctttc attgctggga tctgacgaat
    11881 ttcttgtagt gagatttttt cttcatttgc cccataccat ctaaaagtca tttccatagt
    11941 tactttcctc caacttctgt tatatattta ttgattgttt tacgaactgc ttgaggacct
    12001 actagcattt cgcaaaagat tttttcagtt ttctttccta ccccaacttg atataaatct
    12061 aaaccaaaga tttctttatt ttctaaaatt tcctgtaccg cacaatgaat ctttgaagga
    12121 tcttgttcac ctaatttcaa tactgataat ttatcctgca actctaccaa taacggatca
    12181 ggacttggca caaaattttc cccttgatca tcgactgcca gtaaataacg taaccaagca
    12241 gcaatagcga taggaataaa tgttagattt tctgcatttc cgtctttttc gacatacttt
    12301 ttaattgttt caccatagcg aatcgctact ttttgagaag tatctgttgc aattcgttgt
    12361 ggtgtatctg gaatataggg attaggcaaa cgtttattaa ttacttcatc aataaattgt
    12421 tttggatcaa taatgcctgg attttcaact actggtaaac cttctaaata acctattcct
    12481 ttgattaaac caaccaaatc atcatcctgc atctctgctg aaattgattg atatcctagc
    12541 agacaacctg ttactgccaa agcagtatga agtggattca agcttgtcgt aaccttcatg
    12601 atgtctgctt tatcaaccgt ctctctatct gtcataatca caccagcctt ttccaattta
    12661 ggccggccat ttggaaaact atcttcaata actaaataat gaactacctc agtattagtg
    12721 aaagcagcaa tattggtatg tttttttgtg tgaatgatat ctaaatcctc gagccccatc
    12781 atcaatagat cttcctttac attctctgaa ggatttggcg taattcgatc aatcatactc
    12841 caaggaaaag tcactttttc tttatccttt aaataagcaa taaatttttc agaaacatat
    12901 ccttcttttt gccaagcttc tgcaatcgta aaaatactat cttgaaaacg ttgaccattc
    12961 tgtgagaaat tatcagtaga aaccatcgca atcggcaact ctccagcatt aaatctgcta
    13021 tataacaagg atgttacaat actcatcgta tgttgaggat tgctaggtcc agatttgata
    13081 tcagctttga ctaccgaaaa gaattgccct ttagaatctt ttaaactgta acctttttca
    13141 gtaatagtaa acgttgtaaa ctgtaattta ggatcttcaa aatatttaac cactctttga
    13201 tagtccgcta tattcttcgg attgcaatat aaactatcag ccgttactgc caaaagtctt
    13261 tttttgagtt caccatctcc actcataaca atttccaaaa tgtcattgtt atagtcatga
    13321 taagcttttt ccactacttc ttcatcaaat gtttcacaca caactactcc tgtttctaat
    13381 tcattttgat ctgctaagca ttgagcaatt tctgcatgaa atcctcgata aagatttcct
    13441 ccaccaaaat gaagccatac tggatgttgc tggccttctt gcttaacttc tttgacatca
    13501 aaacacggca gtagaatctg catttcattg aattcttcga tagaattttg ccaattttta
    13561 atcgaaacca taattaacct cctcaaactg atatgttagt tttgatacat tttatatttt
    13621 aaaacccatt gtaaccgttg tcaatataaa aagggaataa acttgctttt ttctaccata
    13681 tcagaatgat tgtatttttt attcagaaaa ataaaatact ccttcttttt ggactgattt
    13741 tatcgaaact tattttttct ttttttcatg tattctttta tttttataac tagtgtatta
    13801 cttcaaaatt tgatattata tggcatgaac agaattaaaa tatcagttaa aataaaagtt
    13861 aaggagcatt gtgtatgaca attaaaacta gtctccaaaa tcaagcttac caatctattc
    13921 gccgacaaat tatctatgct gacttagaac ctggaaaaaa agtatcagaa aaaaaattag
    13981 aagaaacact ttctattggt cgtacaccaa tacgtgaagc actgattcaa ctccgacaac
    14041 aaggtcttgt tgatacaatt cctcaaagcg gaaattatat ctcattaatt gatttagatt
    14101 cggccaaaaa tgctcgattt gtcagagaac atttggaacg acaaattatg ttagagtgtt
    14161 gtgccaaaat gaataaccaa aaaaaacgga ttttagaaac tataatttca gaacaagaaa
    14221 aagctgttag tcaaaaaaat gctcgtagtt tttttcataa tgataattta ttccataaag
    14281 cttgttttga aattgcagag cgagaagaag tatggcaatg gttagaaaat aacaatacac
    14341 acttagaacg atttcgatgg ctacgagtaa aaacggaagg attaaagtgg gaaaaaatta
    14401 tggaacaaca ttatcaacta tttgaggcat taacaaaaca agatccagaa gaagctaact
    14461 ttctaacatc gttgcatctt catttaatgc ttaatgagca aaatattgtt ttagctactc
    14521 atccaaaata tttcaaaaat atataacttt taactctttt taaattaaat ggttgttctg
    14581 atcagaaaaa tatcgcttgt tttcttatta tgtaatatat ttcataaact attctgcata
    14641 acaactattg tttgtacttt ttacattgga taactaatta tgactgctga taacttttga
    14701 tattaaacta gtatctccaa tacaaataaa aaatagatat cttgttcatc aaaattagtt
    14761 cgtggatact taccttcatt tacatcattc agcggtttcc cattttcttt tattctatta
    14821 tttcattttc taatagactt ggcttcattt cgcaatactt tttttcaata ggcatcaaat
    14881 tggtgttgtt tagatattta gttgtagttt tgtgacatga taagtatgct cctttttctc
    14941 ttttccacta atacaacgat caaagggtgc ttttttcaaa aaactagaaa aatcaaaata
    15001 agattcgtat tttgattcta tatatcctgt ttcaactaca tcttatattt cacaatagaa
    15061 taaatagcct tttgcatagc tgcttaactt ataagaaatt gcaatttact tcttcaaagt
    15121 gaaaacgaat atgagtaaaa taaaattatt cttcttacag ataattaaaa atagcgcgta
    15181 acaaaaatcg gcattcaatc acataattag gattgatgcc gattacttat attctacgta
    15241 tagttttagt attcttattt tttatcacca gtaaccaatt gagaacagcc ctaaagcaga
    15301 atagtctttt atctcaaaac gcttaatttc aggcttagga atatgaataa tcttttgagt
    15361 atattctttc tcttttaatc ttactgaaga aataccactg cctatctttt ttacaaatat
    15421 ttcatttggt gtacagacta ataaaacaat atttgtaatc aatccttgca ctaaagaatt
    15481 aaaaggaaga ctatttaaaa cagggtgtgc ataactataa catgtgaagt agttattttg
    15541 aactttaact tttaaaaact ttaaaaataa tcttatttgt tcttctaaac aatcatctat
    15601 actcatataa tcactccact aattaatctc cccaaaaaga cacagcatta agagatatac
    15661 caacacaaca gtgcaaataa ctctacatct tccttcgcaa ccttatttca ataaaccata
    15721 aaaattattt tttaatagaa actgaaaatt aaaactagaa aaagtagttt taccgaatgt
    15781 aagagcatca tcaccatcaa tatagaaata cattcttttc cagttacatt taatttttaa
    15841 acaaaattct ccccaaaaag gaactttttc tagtgaaaac ttggtaatct ctttgtaatt
    15901 aattcttgtt aaagaataat taaacacttc atttttactt gttatttttt cattgactat
    15961 aactagttca tctggtaaaa aaattaacca acaaacatcg acaaacagta aatgatataa
    16021 tccatttcca cctccaagca tattcaatac tggtgaacat gccttagaaa cacgaatata
    16081 gttatggttt aaatagatat tttctttaaa cattgcttgt ttaaaagcca tatgctcttg
    16141 ttctaaactt ttcataaact tttactctaa tgcacagcta gcagcagctg ctgcaattcc
    16201 tgctacaata tttaccttag ctaactcttt agctgcagct tttcctaatt gtttttctgc
    16261 aatttttaat aataaatccg cagctttttc aaaattaaaa gcttttaatg cttcaataaa
    16321 atctccctgc gtacctatag cccaagccac tcctcctcca ggaagagaat taatggctac
    16381 acatccagca tatcgtttcc aatcaacttt ctccattcta ggaacaataa tatgttcata
    16441 aaagactctt gctgctcttc cttgttcgtt atcttgactg attcgttcac gaatagcacc
    16501 aaaatccttt atatggtata caccatgttc gtctaaaaaa ccaactgtat caaaataaaa
    16561 agttaattca tctactaatt tattctttat ttctaaatca actgtattca ctttttctgt
    16621 ggcatacaca cttgttccag tactaacaaa agtacttaaa cctaataaga aaacacctaa
    16681 aacaccaaat attttaatta ttcttttcat aatttctcct ccataaaaaa taagttactt
    16741 tttaaatatc ttgtttatga attcattccc caaaggcctt ttaagattga tacagcagtc
    16801 cgttcacttc ttttagactt gtcatacaag tcttttaaat gatcccatat cagactagtt
    16861 tgtctatcta gcttcaatcc attaaacgct aatgaacggt tcattttttc tattacttta
    16921 gataaagcta cagaaatttt tataccttca caacgcgcat cttggatttc aataatagta
    16981 tcatcaatta gtttttgaat ttcttgccta tcaacatatt caatcttaga aagagaatct
    17041 tttaaagcta ctaatgattc aacgatttct tttttctctt cagacatttt cttcctcctt
    17101 ctagtgaccc gtaaagccat gtagagcaga gtccattgaa ccagtaatta cactatctac
    17161 aacgccattc caatttactc tacattttcc atttttcaga tttgtcggtc catacggata
    17221 gcctttttga cattcaatgt tcggattata ccagatagga ttataccatt cagccgcaga
    17281 agcagattca gtcgatacaa acaatcccac accaacaaat ccaatacaca tcacactata
    17341 gccaattagt tttttcatct cgtatccatc tcctaaaaaa tagaatagtt cttatagtta
    17401 ttcataagac atattttttc cgtttttgtt ttatcctttc tgtcctataa caactttttt
    17461 caagtaaaga atgacatagt ttttcttaaa aaaacagtct gtttttttct atttcttcgg
    17521 tgtataataa atatgagtgt tcatttttta ttttaatacg cactccgtac ataataaatc
    17581 ttgatcgcat caatcttttg agcttcttga tctactttca attgaagtaa tacaaattga
    17641 gtaaccttat tcattgtttc ttctccaaat aacaaatatt gatccggatt ctctatatct
    17701 tgtgtcacct ggtaaagttt cccagttgtt ttcatttgta catgcgggtc tacatcaata
    17761 ctattgtctt taatacaacg atctgtcata tagtccctca cagcttgatt gcgtttataa
    17821 acatctgtga aattactcca ttttctagca aaatctttta agaaattttt tgtcatttca
    17881 tctatttgca tttgttgcgc tgtctcgtct tctaatgaac caatttgact gttactttca
    17941 gtactttgaa gagttccact tgtttctttt actgcttcga ttgtttcttc tgtcgttctc
    18001 aattgtgttt tttgtttttc agaagaaaac caatgacaac cagtaagacc tatcaaacat
    18061 aaccaactaa atactaaaat tatccctttt ttcacgtttc tagtcactgc ctttcttatt
    18121 tcaccttacg aaccagacta cgaatttttg tttgattgta cgtgcgttga taccgagcca
    18181 taatccgtcc ttgctcggca ttctgttcca cactagagaa atgttgtccg ccatatgaaa
    18241 catctgttat aattccggtg tgaccataga ttccaggaga caatgcacca cctgcttgcc
    18301 aattcaccac atctcctgct tgtaaatcac ttggttttgg gttcatgatt acttgccaac
    18361 cataggttgt ccagttataa tcttccccta ttaacatcgc aaacatgtgt ccagaaccca
    18421 ttaactgtgg gccacctaat tgagatacat accatgccgt accaccataa cattccccat
    18481 tatttacgga tcgtccaatg atccgatcca aaaccttcgc attgccttta ctttttcctg
    18541 caataagcga agtttttttt gttggtaggc tattccaatg cttgatcgca aaagtatcat
    18601 attccgttaa gttataggac gttatgatac tcattgctcc tcgataatac ggactccctt
    18661 cggtaatacc tgctgccgca tagcctccac gacctagaat caataaacaa cttccaggat
    18721 ctttattgcc cacacattga ttaaagttgc tttggctcgc caccataaag ccataatagt
    18781 cataacaagc ttttaagttc ggaaacttca tatagaaacc accttcagaa ccaccaattc
    18841 cacgtgcaga accttgtggg tagggacaac caggaaacca ggtaatccca aaaaagttcg
    18901 tatcgtttct tccagattgt gactgtccat aagctgattc atagcctaat tgagaaagaa
    18961 tcacactcgg taataactga tactttacag ctgcaccaac tgctgcttgc gcatgttcat
    19021 ctgtgattgg accacgtcct ttaatctctg aaaaaatcgg taatccttcg gtatattccc
    19081 cattaaaagc gacagctaga cctgtagctt ctcctccatg ctcagaaagt tctcctgaaa
    19141 aaaagaatgg caatagaaaa aagggaagaa taaagaaaag aagacaacct agacaccctt
    19201 tcttcatttc ttcctcatcc tttcttcgat aatggttttt ggactgttcg tccttttggt
    19261 aaagtaaaat cagttcctgg ttttgcgtcc aaaatcggca gtgttttagg atccttttct
    19321 attttttccg attgctctgt tggcttatct aaagaagaaa atgcaggttg taacgatttt
    19381 ggtgcggaaa tcgacggttt actttcagac gaacgttgcc ccggttgttg cacagaacga
    19441 tttcctgata gagtggctac cgacgaatta ggaacagagt attggttcaa taactgctgc
    19501 attgctggat aactcccatt tttcgcctga tttttcactt ggcgaatctg ttgtgaaaga
    19561 gaaccagcag ctgttaattg tggcacgggt acttttccag aaggcaacgg aatcgattga
    19621 ccaacaaaag cgataccttt atttaacaat ggttttcttt gattattccc ttgttgctta
    19681 ctcaattgtg ccaatgattg tacctgttgt tttggtctta ctgaattcat ggacgaattt
    19741 ggaatcaaac catttgaaag accagaattc cactctgttt tcgatttggt agaagacatt
    19801 tcaggctcta ccccatgata acgaacatga cgaccactat aaggcaaggc ttgatttgaa
    19861 cgcccaccta gttcaaaggg attaaccact tgcctccctt ttaccgattc ttgtggtgta
    19921 cgtttttgtt gaaacttttg aaatccatgt atcgctgcag aagcgagtgg attcgttgct
    19981 cgatacacat tccctgctaa tcctgcacct ttgattgcca aattttgtcc agcagttgat
    20041 agttgaccag gcagttgttt catttgagac aaagaatgac ttgctatgtt tttcgtgttg
    20101 tttatagttt gatctgcagc tcctaaccct agtttcttta ataaatcttt ccgttttaca
    20161 atgagtaaaa ttgataggag tgctttgaca aacatatttc ctaaaaaacc aaaaacagta
    20221 ttcattggaa ttaaatcgtc tactatgtta tagatcaaaa atgccaccaa aataatcaca
    20281 ctgtaaaaag atttttgaaa catcaagccc aaaaaggact ttaaggtatt catgagcata
    20341 taatcaaata ctggaacaaa agaagcgagt aatgaaaaag gaatcacaag taataaacac
    20401 aacaccaaca tttgaaagat aaaacgaatc atgccaatca ctacaagtgg taatccaata
    20461 cttagattaa gcaatggcac catagaacca acgactgctt tataaacagc tttagttggt
    20521 tgaatataga cacgataagc cttctttttc cctctatctt ctcctgcagc agtggtcact
    20581 tttgtctcaa tatcagataa ttcttcactt gacgcttcct tggctagaaa ttcttgtggt
    20641 tcaatctctg cttgatacaa ttcttctaaa tttgttgtcc cataatttaa caatatatac
    20701 ggatcaacaa cagccgcttt ataataaagt tggcgcactt tttgaatggc ttccttttgt
    20761 gtcgttggca ctaaaacacc attgacatct tttgtcgcca attcatctag actatttgta
    20821 gcagaaaaaa taaagccttc tacctccacg gacaaatcat ttaacccttt ggtaaaagct
    20881 tctcctttac taggtacgtt actaccatag ccaaaccaaa ccattgaaaa aatgacaacg
    20941 aagagaaatc gaataaacac catttttgcg taatgtttcc ctctaaatat acgaagagta
    21001 aatagatata acacatacaa gacgacaatc cccgcaccaa taggatcgta tatttttgaa
    21061 taaatagtat ccgaaaaagt gaaaaactgg tgaattaact cgttcattgc agctccttca
    21121 tagagcttct caatgacaaa atcaaggcct tgccaaatca atttacttaa actaaagaac
    21181 atattcgtca tcatttttag aaaatctgtg ccatttgccc caaataacat tttgcctaat
    21241 gaaaattcac tatcagataa ataagaagaa aaggtatcaa tatgaaattt cccaatctca
    21301 tagatcgatt gatccacctg cttttctgcc gcatacacca atccaccaac aaaaagcagt
    21361 ccgaatccaa tcgttaaaaa aaacaaaacg caccatttct tttccttatg ctttatataa
    21421 gccattgttt cacctcattt ctattgcatg attaacgtat cctgttcttc tacttgagag
    21481 tgacttgttt tttccgttgt ttgtaatgca gcggtcattt cttcaaacaa actgtgtaca
    21541 ttgagttttc ctacacgtcc atagggatct aacatccaac actgtccttt aatcatgtgg
    21601 ctcatttcag ctaagttcgc ttcatttact tccaaacgta aatgattcaa aatcttttct
    21661 cgctcactgt cttcatcaaa agcaaagacg acaccaaaat tccctttttc tttatctgaa
    21721 cctaagtcac caataaattg tgtatctaac actaattgat tcatctggga acgccccaca
    21781 cgtgccattg ctgcaataat actacgtcct gcgttcgaat tattaaatac ccatgcttct
    21841 gtaaaataaa tcgctgtttt cttactacta tctcgttttc caaacatttc acaaaaacga
    21901 cctaaactaa tcatcaaaca caaagacttt cgatccgcat ctgtatatag ttctggtcgg
    21961 acattgtcat ttggtaattt caaatcttgg atctctaaaa tcgttgtttt ggcattaaag
    22021 tctaatcccg ggttttctcc ataagaaaat cctaaacgta aaatcgaatc ttctaccgtc
    22081 aagcgtaaaa actcaccata ttctcgaacc tctttttgtt ccatttgttc taaatagtcg
    22141 accacatgca tcaagccaac ttgttgtccg gcttcttttt gaactaaaac ttcttggatt
    22201 ccctttaata ccgccccttt taaaaggtga ttggtaccta acggacttaa ctcatcaatc
    22261 atatcctggg ctacttgttt cgcatctact cgggataaac aaacaattgg atctaataca
    22321 ccataattac ggggatttgt agcatctaac gtgacataac tcattttttg caaatgttct
    22381 acaaacaaag ggtaatgttt ctgataatac gggtcttgaa tgagtttcgt aaaccatttg
    22441 cgcttttctc ctttgggatc cacaaataaa ctttgtacat tcataaacga actatacaaa
    22501 aagagcaagc caactaaaaa ggtcttccct ttaccggttt ttccagttac tgctacatga
    22561 ggcgcatcaa acaacgcacc tttgattcct tccgcaatgg ctagaagatt caaaaagaca
    22621 aaacgatttg acgcataaat taattcttct aatggtgttt tttctcctcg agaaccacca
    22681 tcccctaatg tatcttgccg accaatatac cagccggatt ccatacctaa ttctgatact
    22741 gctgaaaaca accattcgcc aactgcttct acagttgttc ggtgcttcca atgtaactgc
    22801 cgtcccaatg gttgccctaa taaacattta tagaacaatt ctcgttgatc attttttgca
    22861 cggtggatat ggataatcgt atgaagttgt tgaataaccg ttgcactatt ttgacgaact
    22921 tcttcaaccg tttgaccgta tacaataaaa catgcgatcc aatcgacgac aggttgccca
    22981 ttatctactc gttgctttaa atgttttact aatcctcgaa cagttaataa gcgttcacta
    23041 ggttcttcat cattttgaac caattcctta tgctctgttt tgaaccgttc cgatagccaa
    23101 ttcagtttta aaccaatacc tccctgtcct ttcaagcgtg gatagtgaat tttcattcgc
    23161 aattctgctg ggaaagaaag atcctgagca aattgaaata gatcacaatt tctcatattt
    23221 tcaggtgttt ccccaatagg caacaatgct aaataactac tccctaactc atcttctaat
    23281 tgaagaaggc ctttatgttc cttcggtata cgtacatacg ttccttgatt gtctttcagt
    23341 acttcccaat tattttgttc ttctactttg tgagccattc ctcgaatata ttgcagacga
    23401 ttgagataca acagctcttt ttttactaag ggacgaatag aaaagctata aagtaattgt
    23461 gtcacttctt ttacataagg atcactttca gaaaacaaag tttccaaatc atctacttct
    23521 aatccaaata agcgtgctaa acttcctgct aaatctaacc agattagatt tattacatca
    23581 tgaaaactct ccaccgttgc tttttctttg actttgattc ctaaaataaa tgaaggacga
    23641 tagacttgac cttctcgttc caacaatgtc actgtttctt ttgcataata cgcaccaatt
    23701 gcttgactat cgggagaaaa tccctttcct aatgtgtcaa acttcgtccg taaattcatt
    23761 gttcgtggat acatcaccaa ctccacatct tcataatctg ctaaaagcaa cagtaaacga
    23821 gccatcattt cttttatttc ctgtgtcttt tttggtgtgt tttttgaaat tgttcgtgga
    23881 aaaacatgat agtaggccca gatacaatcc tctccattta acaaacaatt tttcttgaat
    23941 gcttttactg gttcttttac aagcaccaat gaatttcacc tcccaataaa aaaggaacaa
    24001 ccagttgatt gtcccttttt ctaatcctct aaataaacat acttattcac aaaaagtaat
    24061 tcttccaatg cattgtttga taccttgtcc cagttataat acacacaatc accattcatc
    24121 atacgaatca tataacaaaa ccaatcccat aaataaaaat gcactttttt tccatcaggt
    24181 tttagttttg ccagtgctaa cacacataaa taggggagtc ctatataaaa aacaactcct
    24241 gctggtggaa aaaaagaaat gacccaacca ataaatgaac gtaaaaataa atattcaaag
    24301 attacgacca acaaaaaagt tgctgcattg actaatgcaa ctggaaatgg aagacgccaa
    24361 ttgcttgtaa tctgttgtac gcgataaggt tccgcataaa caatcgaata atcataaggt
    24421 tcccaatcca cttcactatc ctcctaatcc ataaataatt tttcaatgat tttaccaaac
    24481 gcatcaaata cacgtgttgg atcatttaag aagaaataaa ctgcggcacc tgctgcgata
    24541 gatattaatg catttcctac ttttgatttc ataaaatttc gcaatcccag ataaacaacc
    24601 accattatta aaaaatagcc accttgcgtt aatataaaat ctacaattcc cttcagtgtc
    24661 atttccgttc ttctcctttc ctatccaacc aattatgtgt taatttttca acataatact
    24721 gatttgtttt tttcgtaatg acaatcgtca tttgttcttt ttgtaaaagt gacgtatcac
    24781 catctcgaaa gacgaccgtt gcttttacaa taaaaggttt tttcgtttct ttataacgca
    24841 atactttcat ctctacttga tcaactttag ctgtttgatt gagtccttca ggttctttca
    24901 tcatgtatga catatctttt gcattgtttt tcgcatactt atctaagaaa tcttccacaa
    24961 atccttcaac atctttcgct tccgacgcat caaccgtttc gtataatgtg tcatcataag
    25021 taatcattcg ttgtttttct gtattctttg gtagtgccgt aaaataagga taagcaataa
    25081 tacgacagcc cttgtttgaa atagaaaagg gaagattgag tacttgtgtg attgtcacac
    25141 ttgtttcttt cttactctct ggattcatcg agcgaatatc ataagttact ttataactag
    25201 cagttggaat ggtttcaatt tcttttaatc caataaacga agcagcagtt aattttcgaa
    25261 cacctgaaac acttcctggt tcttgaataa agttttgtgc ataaaactct ttttttaatg
    25321 tttcttgacg ttgttgttct tgttcatgat tatcgaatgt attcatatac aaagcaacaa
    25381 aacgattcat aaaggattca atttcaggtg tgtacgttaa ttctgaccga ctttgtactt
    25441 ctttcttttg taattgttgg atttcatctt tcaaaaacga cacttgaacc ttcgttttca
    25501 tggattgaaa aaatgccaag ccccctgaaa aacaaagaaa taaaaccaaa caccaaatcc
    25561 atttcactgc tttttttgaa tggattttct tttgcttcgg tactttctct gtataaactt
    25621 tttctttccg ccgtagttgt cgttttttca taagctactc cttctagtat gtttttacta
    25681 gtacgtacga ttgacaacga taagcttgtt tttctgaaaa atagtccatt caattaccct
    25741 cattttctat tccttttctc tttcttttat atccaacaaa tccagcaata cttgtcaaca
    25801 ctcctcctag aacagaaagt gcaacatgta tttcttcacc agtctttggt aagacttttg
    25861 tttttccatc tgctgttttg atttcaatat tgccacttgg aagtttcttt acaggaatcg
    25921 acaaatcctt taccaaattc ccttcactat cttggattaa tggaatacca tcttttacac
    25981 caacaattgt ttgatcacct gctactttta atggggtggt tggtgttgga atatgggtca
    26041 attcctctac attactagtg acaatcggta cactcattcc ttgagaagta ttcgtcgtaa
    26101 tttcaccgct tggggttacc gatactgtga cttcttttgc tggaacaata ggtttatttt
    26161 cttttggaat tgcttctgat ttttcaacag gttgtttcgg ttcttctttt tgttcttcac
    26221 tggtagacga catcgttggc tgttccgtac ttgacgaatc agtattcttt tcagaagaac
    26281 tggttgttcc tgattgttcc ggagttgtga ctatacttga atccgttgtt gttgaactat
    26341 gcacaccttc ttcttcgatc gaatcagtcg gtaaagttga ttcaggaaac tctggttctg
    26401 gtgtcactgg ctctttttca ggtttctctg actgcaattg ttcaggttct gctggttttt
    26461 ccgttgttcc tccatttagc tctgtctcaa catctggtaa tccttcccct ggcaatgttt
    26521 ctacaatttc tgacttaggt gtttctacag tttcatctgc ataaaccaat gaactcccta
    26581 attgaaacga aaataatgaa attcctagtg ttgttacgac tgctaatgtt gtttttttca
    26641 tgattattcc tccaattttt tatgcaattc gtgttttgtt catagacgcc gcactaatat
    26701 tatctgaacg ataaaagaac tcccgtccgt tttcttctaa cccaacatat ggattatttt
    26761 tgaataattg aatcaatagt tcactggtgt tgtattttgg atagtttgca aaaaaataat
    26821 actgtgcttg tcgcccatcc gaaaattcaa caagtaattc ataacgatac cgcttcaatc
    26881 cttttcgttg ttttaaagga tctctatacc aacttgtcca tcgttccatt cgtggataga
    26941 gatagacacg atacacatag aacaatgcca taccacatac caccaaaaat aataatcgcc
    27001 acataaaaat tccccctttt cttctacctt tcttgaatca tcgaacattc ataccctcta
    27061 tagagatttg aaaaatccat catcaattgt tcatataaac gttgttgcaa atagcgattg
    27121 tttcgaatac ataattcttc atagccatca atcacttgat cttctttttc atagcatctt
    27181 gtagctctat gacgctcagc ttgcatgaca taaccaaact ctgcaccata tcgttctact
    27241 gttaataact gttgactacg caataatgca atataacaat cacaaaaatg ttcaaccgac
    27301 atttgatttt tctcacgttt gtgaaatagg tattctttag aaagcacatt attcgttaaa
    27361 caatctgata aatagcgata atctggcggt cggttatttt catctgtgaa tttttcccat
    27421 aataaactga tttttattcg ttcagcggct agatagtctt gttcgcgtgg ataaaattca
    27481 tcaatcgcac aaagtttttt atcacctgaa taaacaaatc catataatgc gaaacgaact
    27541 cttccttttc aattggctct cctaaaaatt ccagtgacat accatcttct ccttcctaaa
    27601 aaaaataaaa aagcagaaac cgatttggct tctacttttc tttcctttta tagctctttt
    27661 ttacggaaga atccgcaaat gacatttttt caaaaaatca atcggcacaa gttcacgaaa
    27721 acttggagca attttggata gaatcacttc cccatcttgt aaaatacaat cataaaaatc
    27781 atcagttact tgatacttac gcttcttaca ataattgata aaatagtagc gatcattttc
    27841 tatttccatt cgttgttcta ctaagcgcat acgaacatca tcatagaaat aagccacaaa
    27901 tcgcccttca agttcatgtt tttcaatggg atactcttct ggtaacaatc tattttttcg
    27961 tcgtttatac attgctggat accttagaag aagttcatct aaacgtctgt cagtatatgg
    28021 taactgacga atcaacgatt ctaatcgttc tttatacaga tagaataatt ggcgcaagca
    28081 atagtgtacc gcctctggat tttctaatac tgttggatca cgtgaccaat acgcaccaac
    28141 ataaatcata atttttttca tttagacaat cgcaccagca atactaatga ccgatccaca
    28201 ataggtagaa caagtggcat agcgaccaat ttcctctaat tctatctcaa tctcttctaa
    28261 agaaagatat gtctgttctt ctgttggctg gcgactcatt tcccaagtga cagtcaccaa
    28321 tgaaatttct tccataagag gtttttcgct gctaagtgct gccacacagt tttcatatat
    28381 cttcatttta tcgcagcctt ttttaaccgc taaaatcgca ggtattggca atgaaaatcg
    28441 ataaaagcga atgaattcta gccttccttt ccttcggcta aattccaact cttcgagttc
    28501 ttgttcgtat cccttacgaa cttctaataa gcgtgcaatt tcttgccagt tctctttttc
    28561 ctgataacgt ccagctttta ccgcttgttc aatataagga actcgaaaac gaaaataaga
    28621 caaatcaacc atcttttcat ttaatgcttc gattgcagcc tttaaatcca acaggcgcag
    28681 ccattctgtt gtcgtatatg cattcatgca attttccctc ctgacgttcc catccattct
    28741 agatagtttt gttgctcgtc atttagttcg gcattatcaa tcccttcttg tacaaagtct
    28801 cttcctaaaa tacgatctgc ttcttgtaac aactttaatg tcggagctac ttgtttcaaa
    28861 aaccagcgtt ctgaacgatc taatgagaat ttttctggct ttactgtaaa atccaattct
    28921 tccatcgaac gaaataattt tgcccatcgt ttatcaacaa tccgtgcatc actttccagt
    28981 ctatcccaaa caataagttt tgcattaatt aaaccaacgc caatctctcc taaacgtttc
    29041 ggtgaatcac ctaaaataaa tgcttctact gcttgtgttg ctttctcatt ggctaaccgt
    29101 aactcatatc gattataaat accatatttc gttaatgctt ctaattctga aattttttct
    29161 cggttcgcaa tttcaaaacg tttctcataa aaattaaaaa agagaggact ctttcgcgat
    29221 ccaaaataca aagataatcc ttcacttcga aaatagccat catctaaaaa acaaccgcca
    29281 atattctgga atctcttaaa gtccatttct aataaacctg ctttttgttt ttctagtaat
    29341 tcaaagagat cgaaatgttc ttccgtttcc aatccccaaa gttcatctaa cgcaatatcg
    29401 aatcggctac attgcacacg tgtataacca gcttccaact ttccttgatt tttccaaatg
    29461 gaatatagcc atgttcgcca atctgtttgt tgttcacgca tgacttcctc atattcccgg
    29521 caaccttgtc ctgaaaattg cacaagtaca ttttctgtta cagttcgttt tgaatgccag
    29581 aacacccaga tattcccacg aacagaaaga cagtcaaaaa gatacaagcc cgttggacgt
    29641 gtttcaaatt ctgtcagatc cattcgtaat acacgttgaa tcactgtttt gtagtctgtc
    29701 ccaaaaaagg aaagacgcaa ataatcaatc attgctcgaa gatctattcc gcttttcata
    29761 tacaatcgaa agcgttcctt gattcgttgt tcaaaatcct ctgggatttt tcttttccct
    29821 tgttccatct ttctaatgta atcttttgag cagcccatca attgcgcaaa tcttgcttgt
    29881 gatagcggct ttttatctcc acttatatta tgaattgcac ttaacttctt tctgtagctt
    29941 tttagctcaa tcggtgtcat tttctcgctc cttttataaa ataacaaaat cgattttttt
    30001 taacccttta gaaacaccga tatatcaact agtccccctc gttttttggg aaaagtagta
    30061 caactgctga ccttagataa tcacttgata caaaagggtt tataaaactt ttttctatgt
    30121 gttatgttat ttctgccccc catattatat atcggggggc tttacacaaa gaggccgtgc
    30181 gcaagcgcac gacctctttg tgagctgcac acgctgctag cgagtgcgca ttataggccc
    30241 atgcttcgca gccttaatgc gcaccgccag gcagagtgcg gctaccagac tacgtctaga
    30301 gccctcccga tagataataa ctacaaaatt aaatgatcta attttgttat ttcactatat
    30361 ttttcaggag aaaaaacgcg ataaattgac aaagttaaat cctcttctaa atctactcga
    30421 taatgataca atcgagtcaa tcgttctata tcttttttcg ttagcaatac ttgattaata
    30481 acttttcctg taaaaacacg ttctttgcgc aaaaagcggt aatcagttac ttgttcaata
    30541 cgattcaacc aatcataaaa cgttctggaa gaaagagaag gattaatcat tcgtattgct
    30601 gtagctactc tataataaca actctctgcc atttaacttc acctccttag ttgattacaa
    30661 aatatgcgca tcagaaaaac ttgttccttt tggatctttt gctaaataca tttggcgctc
    30721 tagttgttct tgtaacaact gattatcatc tcccatcgtt tgatcttgac tatcctcttt
    30781 tactgtaaaa tcatagacaa tcatttcagt aaatttctca aattctttga taaagtgata
    30841 atctttgtaa acaaatggcg caaaaaactc tacaggtaca tcaaatcctg gaaaagcata
    30901 tccacgacca ggttgatctt tgttgtaaaa tggcttattt ttaaaatctt ctccaaaagt
    30961 cattaaataa ccaatgggag acaatcgacc aacagaaata cggaatgtta aattatcccg
    31021 aacaccactt ggaaaatatt ctgcatctgg tcgttgcatt gctaaaataa tgtacatccc
    31081 tgcttgacga ccctttaata ctaatggctg aatcaattta tcgactctat ttctcgcttc
    31141 catatccaac gaaccataaa aagctgccca ttcatcaaaa aagataaaat gcggtggtaa
    31201 cccataataa gcataatttt tccctggttc atatttagga tctttcatgg ttttcatata
    31261 ggcataccgt tgattcattt cttttaatgc atttcgtaaa caaataatca tttcttcatt
    31321 tattttgtaa aacacatgtc ctttgaatac atcgacgtca cctaatgctg ctaaatctgc
    31381 cgcttttcca tcgcaaatat ctactgtccc aacacttaaa caagcttgaa ttaaagaata
    31441 caataaatag gttttcccac caccgattgc accagcaatc aacatatttg gtgattgatc
    31501 atatacccaa tccaaagttt tcattaaatg aatacgtcca ttttctgcta tacattgatc
    31561 aataggaatc cgaccagaat ctgaaaggaa tacataattg attcgggctt tttctcgttc
    31621 ttcacgaatt aaatcacgca aaaatacttc agataacaaa tgacccattt ttaaaaatcg
    31681 ttcgtgaaaa cgcccaccat ctaaaggaaa agaaaccact aattcttgtt tcttttgata
    31741 aaaataaact tttggtaatc tcattttttc ccttgtttgt ttctcactaa cttgtttctt
    31801 tgtataaaca aaccgattgt caattaacat tcgaacaagt aactgacgcc aataaacaga
    31861 ggcaaaatat ccttctttta gtcgcgacca atgcatcaac cctaaaatta acccactaac
    31921 cagcaacaaa tacaacacaa tacttattcc aggaataaga tacatttgcc aattcgaaaa
    31981 cgtacttaaa cgtggataaa atactttcca actaaaccaa cctaacagaa tcaaaaatgg
    32041 aaacaaaaag aaaccataat agcaaaacca taaataacga ttgaaatagc gaattcgccg
    32101 accacgatac ttgaaaaaat gagctttcaa ttgtcacatt cctcctttct gtttttactt
    32161 ttcctgtgct aaaaactttt gacaaaaagc aactaataca ggaatatcac atttagtaaa
    32221 aaaacataat cgaaaaagat ttaatcgatt tttataaggg tgtgcacaca tattacatat
    32281 tcgtactata cgaatccaaa tcacttcctg atgatcttgt ttccactggt acggtaatga
    32341 aaaacgaaca agatcacgta aaaacataca ctgcccaata accgcacaaa tatatgcatt
    32401 tgtttgtaca aaaatcgttg gattgtctcc aaaatactca atcaattgtt ggatattttg
    32461 ataacaagca caatctctca aagtatttga ttggttttat ctgaattcaa aatctcccct
    32521 tccttctatc ttagataaaa agaataggaa gactccttcc tattctttca aaaaaacctt
    32581 attttttctc tttttcctta gaatcaacac ttggttgttt ttgatctaaa cctttttctt
    32641 gtgattgttt catattagga ttatttgttg gagcttctac tttctctaat cctttcgcat
    32701 aaatcactaa atctgaatat tcacgattgc catcttgtgc tggaatatat accacatgat
    32761 attctggatc aattaatttc acaggatcac gtcgtttaaa accagtcaaa tctacatctg
    32821 ctggaaattt aactcgtcgt gcaatctttg gttcatctgg atttccaaaa actaattgtg
    32881 ctcgctgtga tcgaatttct cccgtataat cgcctgtttc attatcaaat acacgatcag
    32941 actcttctaa tgcgccaaag cgtacggctc ctaaacaagt ttcatctaat gcttctgtaa
    33001 tgtcataatt atttggaaat tttaatccca tcttacaaaa cctccccaat ttttacacca
    33061 gttaaaaaga caccaacatc ttgatagcca gttgttcgac gctctgtttg tcccatatca
    33121 tttgtttcac gactattcac tcgttcttta cgaaaaacaa aataagcttc ttcaaatgaa
    33181 atacgcacct ctttttctgg taatcgtaat cttttatcct cttcagctgt gagataaaca
    33241 aaaaaagcag gctgttcttc tcgcgaacac tctgcttgta attgaacata tcgcccagac
    33301 acaccattaa tttcctttgg tggattaggt tcccgtgaac ccaataaaaa tacttgacct
    33361 aaaaactctt tcttcatacg caatgctttt tctgccataa agtttttcct cctcttaaaa
    33421 accaaaataa attctaaata tttctacatt acaatcaaac aagcggttaa aaatcctaac
    33481 cgcttgttcc tcatgactaa tctttggctt tacgtacttt ataaagtgtt atacctaaag
    33541 caatgactaa tactactaat ccaagaacca taagtatact acttgtttgt tcacctgttt
    33601 ttggcaacat tggtacaaca gtagctggtt taacccgttg ttctggtttc actggttgcg
    33661 gtggttttgg cgcttccaca atttgaaccg tttgatcttt gtttgttaga tctacattgt
    33721 gtttcgccac ttcttcaaac gtttctttct catcttccgt tttcgcttgg agccattccg
    33781 caaaactcaa gccttttcct gcaagattgc gaccgtccac taagaattca aataagaatt
    33841 ccatcatttc tttatcggcc gcaaagactt tttccgcatg agtgccttca aatggtgtgc
    33901 cgtctggtgt taagtagcct tgaacaatta agcgatagat ttgaccaatc gcaagaccgt
    33961 ctactttgac ccattcaagc acagtttgat ttggcaaggc caagatctct tttccgccat
    34021 ttttattcgt cgctttcgtc gtaatggttg gattactgat tttgatggtt tggtcattgt
    34081 cggtaatatc tgcgtgagaa gccaataata cgccttctct aaacagatct tcaaagacca
    34141 cgacttcttt gcctcgcaac gcacgtgcgt ctagaataaa gtctagattg actgtaccat
    34201 ccgttgtttc tgccacaaac gttaaggtac ttgtgacttc ttttccatct actagcactg
    34261 gtttttccgt tactttgtcc attagaacac cgttgactgt gtatgttttt ccaacgacca
    34321 aatcgtggta tttcacagcg tctgtaatgg tgactttcgt taatggatta acctctttca
    34381 agccagtggg tttatgtgta gccgttgtac gtacacttgg gttagttact cgtaccgttt
    34441 gccctttgtc gttgatgtct ttatggtttg ctagttcttc atcatttcta aaaagacttt
    34501 caaacacgac gatttcacga ccatttatac ctgtcaaatc aaaggtaaat ggtacgatca
    34561 ccgtttcatt ttctgctttg gcaataaagc caacactcgt ttctaccgta tttccatgca
    34621 caagcaaggg ttcaccggtt gctttatcca ttaagatccc tttgaccaag tatgcttttc
    34681 ctggaagaat ctcggtaatt tcaacggtat cgtttaaggt aaacaatcct gttgggtctg
    34741 cgactgtcaa tccgtcttca aagacagccg tggtatgaac ggttggatta ttcactttca
    34801 cactttgggc ttcatcgttg atatccgcat gtgctgcaac ttcaatgcca tcacggaaaa
    34861 gtttttcaaa aacaacgatc gtttgacctt tcagaacact agcattaacc acaaattcaa
    34921 ggtcttttgt gccattgact ttgtctgcaa taaaggccaa ggtacttgtg atttctttgc
    34981 catcttgtaa aattggcgca ttcgttgcct tgttcatcaa tactcctgaa atggtgtatt
    35041 cttttccgac aaacaagttg gtataagaaa cactgtcttt aatgacgatc gtttctaatg
    35101 gatcaaccac tttttcacca tcggctttat ttgacgcttg tgtttctagt tttggtggaa
    35161 tcaagtaatt acgtacagaa accactaacg tttccccatc atctggcgca ttttgtttga
    35221 atgcaaccgt gaatgcttgt ttatctgtat ttggttggaa actttctaat ggggcatttt
    35281 ccaagaagta atagtcatcg gcaactagac ctttcactaa aatttccccg ttttgatcag
    35341 tggtatattc accaattgct tgatttttac cgttatacaa ggtaaagttc acacctgcga
    35401 gcggcgtttt cttcttgttc cattcttcat acttgaataa ttttacactt ttccgtgctt
    35461 gacggttcgc aaaatggatc actttgatcg gttctgtatc attggtaatc gagaacacta
    35521 atgggttttg attcaaaacg taatttacgg gggctttgat ttcttccaaa cgatagcgat
    35581 cttttccata agtaagtgta ccgttagtta ggaaaaagcc tttttcattg gttttaaaga
    35641 tatccgttgt ttctgtatca tttggaatct ccattgtgac ataacgattg gctaaagtat
    35701 caaaaatctt gaattctgta ttagcaagtg gaatcacttt tcctgtttct tgatccactt
    35761 tcaccacttt aagacgttgt tcaattactt tatcttctaa aacataatgg aaagtttgcc
    35821 cattttcaga aattgtgact tcaagtggtt caaatagttt atacccttct tttcctttgg
    35881 tttcagaaag aatgtacgta tcaaagacaa cggtattttt accaaaagta gcataaccat
    35941 cattgtctgt cacaacggtt ttcaccactt tgccagttgt ttttgacgtc aaagtgattt
    36001 caatgccagc taattttggt ttgttatctg gattcgttga atcgactaaa tctttattag
    36061 caactttcac taaatcaatg gttcctttga tcacttgatc ttttgcggtc gcattgacag
    36121 tttttccagg ttcaacaaca atttcaattg cttcatcaga aagcacataa ccttttggcg
    36181 ctttgatttc ttttaaaaca tatttgccag gatcaagatc tttaatttct gcctgtactt
    36241 tgccgttaat ttttttcaag gtaatttctt taatcttttt cccatctgct tgatacaaac
    36301 catagaccgc attttctaaa gaagctgcac cttgtgcttt cacaccagtt tccgcatctt
    36361 ctttaaacac acgaatgttt ccttgtttta gaatttgtaa attaataaca gacgcattag
    36421 gttctgttgg atgtaacaca ccaattgttt gagctcctgg acgacgatag gctaatggcg
    36481 caccttgaac tttaatttta ttcaattgaa tttttgcttt atccggtgcc tcttttgtga
    36541 ctgtaatcca tacttcattg ccgtgaatag atacattgac accttttggt ttttgaatgt
    36601 ctttcacata tttcaaaaaa tcatttttat tctttacttt caacgtttcg ccaattttta
    36661 ccgtatgtgt ttgattatta aaagttgctt tttcaccaaa gttattaatc aaacgttgaa
    36721 tttctgcttt tcgacgatca taatcaacac ggatattttt gattgggatt tttgtgccca
    36781 aagcttccca aatcataaat tgtgccgcaa tgtattgttc atcggatttg tctttatttg
    36841 tgacatatcc taaataagag atcaagcttg tttttttccg tacatttgaa tttttcaaat
    36901 agtttttcaa agcagtagct gtataaactt gaccttctgc ggctgagaca ccaggctcaa
    36961 tacaaaacgc cacttgtcca ttaatctcaa aacgaaccat ataatttaaa gtgaagttta
    37021 gattgttcgg actagaagta acaccaatat tttcgcccca atcaattttc cgaccaccta
    37081 aaacagctgc attggttgca cggcgaacac gaaccgaacg attggttggt actgttacta
    37141 acagtgtagg tgtacctgtt tttggaatgt tctgctcttt tttcttttga ttttcaatac
    37201 tagccgtaga ttctttgttt ggtttcgttg gttgattttg actagctgcg gttgaagaga
    37261 ttgttttttc aacgttttcc tcattttttc cttctttgtc agcagtagcc gctggttgtt
    37321 ccactgtttc ttctattcgt ttcttttctt ccgcttgttt ctcagaagac tctggctgca
    37381 cagaaggcgt tgcttcggca gctttttctc cttctagagt ggacgtttct gaagcagggg
    37441 ttgtaattga ggcagtttct tcaactggtt gtgaagtacc aggactattc cctgggtgtt
    37501 gtgtttcccc aatcgtctga tcgagagtcg ttttggaatt gaccgttggc gcttctgtca
    37561 caggggcctg ttcaacagtg gcttcaccag ctgggacccc ggcttctgct ggttggactt
    37621 ctgtcacttc agaagcgact tgggcaatgg cttccatcgt aggttgtata gccgtcgttt
    37681 cttctgcatg tgcttgagca gttcccacca agaaacagaa ttgagaaaaa gccaccaatg
    37741 cgagtgcttt caaccaattc attttcgttt ttgcatacac aagaattcct ccttttcctg
    37801 agaattttat ataataaaac aaaacgccgt taccaaaagt gataacgacg tgaactgtct
    37861 cttctatttt tatctggcgc tcttatctga acacatttca tcaatgattt taccctccca
    37921 ctataattac agaacaaaaa aagaacctgc ttcgtggaaa tcaactgtcc atttcccaat
    37981 tggaatacca gcttttttgg caacttcacc atcaccaaat ctcatgccat accaattact
    38041 accttcatcc ttaatttctt tccaaccata tgacatagct tcatctaatg aatcaaaaat
    38101 catgacacta ttgccaattg ttacaggatc tggcttaaga tcttctggaa gagaaatatc
    38161 aatcatacca taatgatccg attcctcagt attattgtca ttactagcta ctggtttggt
    38221 tgttctactg gcttattttg atacaacaag tactcttatt cttcttttac ttctccgttt
    38281 tcaatttccc attcaaacca ctccgcaaag tcttgcttaa aaccatctac tcgataccta
    38341 ttttgtaaat aggcatcttc tgacgtcgta ggatctaaat aggtaggttt attctctgga
    38401 cgagcataga cacctaccca tgtttcgtaa tctccttcaa aataactatc taccaaatag
    38461 cctttttttc taagaatctc ccgaacttga tttttaatta ttgatacttg ttcaaaacca
    38521 tcactcattc tatcacctca aataactcta gattctcata aatattcccg acaatttcaa
    38581 tcctatcaat gatctctaac aaatcgctac ttatgcttcc ccattcgtat aagaatttcc
    38641 cttccgcaaa ataaattttc cataaacttc ttcatgatcg tcccaaccaa tatcactctc
    38701 gaaaaattcc acgttgttct tatcttttag ctcagtaaat gccataagtt caacatgttt
    38761 tccaacctcg aaacaatcac accacccatc aaccgttaca cgtgtgcctt caatacctaa
    38821 gaaactttgt cctcgtgtat taaacactaa aactttccgc attttttgct cattaattaa
    38881 tcacgcgcga aatctaggaa tcacaactta ttcgcttctt ctttataaat aaaaaaactc
    38941 caataatcgg aaattactat cttttcctca ttcctttttt aaatcttcat acttcttctt
    39001 atctttgtcc taacctaata acacaaattt tgaagaaaaa ctcagtaaaa cctgattctt
    39061 tttttatctt cacaacaacc aactttttct tcagatcctt ttactagaac ttgtatacaa
    39121 aaattgttga atgctgatat aatttgcggc tacttgaaaa aacgatagat gtaaaaagat
    39181 aaatagaatc attttttatt ctatatcagt ctatgattca ttgcttatca atcacccaac
    39241 ccattcgatg ccgttttttt tagagaaatt taaaaaagac cgtacgaatc tcgcattatc
    39301 cgattacttt tccagaaaag atccccaatt ctgtataaat aaccctatct tcttgttggt
    39361 ttcattttct catataagaa ttcagtcaat ctacccacta tgaccattac tacgtccaac
    39421 acaactgaca tattaaccac gtaagtattc cctcacagat ctccgaatct ccatggtatg
    39481 gattcccatc ctgacgctgc agaggacaac atatttcatg tggctctgta cccttttgat
    39541 ttggaaacac tacaaatcaa tactcatcta taacttatca agcgaacttt cgctaggctt
    39601 ctagtgatta ctaaattgtt ggataacata catagcccat tttatctagc tgttattcat
    39661 aacagttagt tcttgtatta cttcttccgc ttgtgttgcc attgagcttg tcaaaaagtt
    39721 acttagaaaa aagctgccag taaagcaact ttcaacaaac cctttttgtt tcttatcata
    39781 tcaagaaacc tccttttata aattttttct ataataaaaa acgtcgataa cttaataagt
    39841 atcgacgtaa actattttta tatcccgtaa atcaaaaatt ctaaagaaag atttcctata
    39901 taagcatatt ggataattcg attagtattg ggtatatctc taccattctc atacctatct
    39961 atggaccatt ttgaaattga aggagaaaaa agctttccaa actcctccct ttctagataa
    40021 taatctttcc taattttcct catccttaat cccatactaa aagaatttat ctttttaaaa
    40081 tcgctaactc tttcatcttt tggaagtata ttcttataat cttctccgta cataaggtaa
    40141 ggaacagtga ccttaccaag ataggcaata ttcattagtt tttcaatatc tggaatatta
    40201 ataccttttt cccatctact tataacattt ttgcctgtat agatggtaaa gtttttacca
    40261 aatttttcaa gcgtctcttc ccggttcttt cggacttctc gtattctttt tcccataaca
    40321 attttatcgt cttttgataa actaaatatc tcactatcac gattaatctc cttcaaaatt
    40381 tctttttcat tacttaatag aaaaatatcg attttttttt gcatttcttt tgacggattt
    40441 ctctttctat ttaacacata actgagtaat acttcactaa ttcctatatt atcagctaac
    40501 tctttgttaa gtaacttatt catatctctg tatgcaatta gtttaccgat gagaatctca
    40561 atcttatctt cctcatcttt tattagagtt tctatattca gaatcttgct tagagtatta
    40621 tctacgtctt tagggatttt tcttgaccct ttttcatatt taactaaagt actttgtgaa
    40681 atacctgcta aatcagctaa ctttttttga gatagttttt tctcttttct tagagattta
    40741 agaacccttc cacttgaatt atcaaccatg aaaaaagcac ctcctatgag atgctttcat
    40801 catatactga cagctaaaaa tcttcaagaa aaatattcca attttgttaa ttttagtatc
    40861 gccgtgataa ccaaatgaca gtttaaaatc ttttatacag ataatcctca gtgttgcatc
    40921 tactcaaaaa ggtttattta ataggttttt cgattgatta taagttattt cacactatct
    40981 tgctcatcca ttttcagaac ggccatgaag gcttcttgcg gaacttcgac ggagccgatt
    41041 tgtttcatcc gcttcttccc ttctttttgt ttctctaaga gtttacgttt acgagaaaca
    41101 tctccaccat aacatttagc caagacgttt ttacgcaagg ctttgatgtc tgaacgggca
    41161 acgatttttt gtccaatagc tgcttggatt ggcacctcaa attgttggcg tgggattagt
    41221 tttttcagtt tttcaacgat tgcttttcca cgttcatagg caaagtctcg gtgaacgata
    41281 aagcttaatg catcgacttt ttctccattc agcaagatgt ccatcttcac taacttgctt
    41341 ttttgataac cagacatttc ataatccaat gaggcatagc ctttcgtgct tgatttcaat
    41401 ttgtcgaaaa agtcaaagac aatttcagaa agcggaatat tatagacgac atttactcgg
    41461 taatcatcta aataatccat cgtaatgaat tctccccgtt ttcgttgaga aagttccatt
    41521 actgcaccga caaaatcatt tgggaccatg atctgtgctt tgacgaatgg ttcttctaca
    41581 tcctgaatcg ttacaggttc aggaaaatct gccgggttat ctactgtagc agtcgtacca
    41641 tccgttttat taacatggta aataacggat ggtgcagtcg tgatcaattc tagattgaat
    41701 tcccgttcca agcgttcttg gacgacatcc atatgaagaa gtccgaggaa tccacagcgg
    41761 aacccaaaac ctaatgcttg agaggtttct ggttcgaatt gtaaagcagc atcattcaat
    41821 tgcagttttt ctaaagcttc ccgcaaatcg ttgtaacgag aagtatcaat tggataaaga
    41881 ccacaataaa ccatcggatt catttttcgg taacctggta aagcttcagc ggcaggattg
    41941 tctgctaacg ttactgtatc ccctactcgt gtatcttgga cagttttgat acttgctgtg
    42001 atataaccga catcaccgac catcaaaaag tctctagcaa ctgcttttgg cgagaagacc
    42061 ccgacctctg taacatcaaa tgttttgcca ttactcatca gtttgatttt gtctccgggt
    42121 ttgaccatac cgtccgtgat ccggacattt agaacaacac cgcggtaact atcataaata
    42181 gagtcaaaga tcaaagcttt tagcggtgca tctaagtctc cacttggtgc aggaacatat
    42241 tccacgatct gctcgagaat atcttcaatc ccaatccctg atttggcact ggctaataca
    42301 gcttcactag catcgattcc gattacgtct tcgatttctt gacggacacg ttcgggatct
    42361 gctgcgggta ggtcgatttt attgatgact ggcaggatct ccaaatcatt gtctaacgct
    42421 aaataaacat tggccaatgt ttgtgcttcg attccttgtg ctgcatcgac cactaaaacg
    42481 gcaccctcac aggcagcaag gcttcgagag acttcatagg tgaagtcgac gtgccctggg
    42541 gtgtcaatca agtgaaagat atatgtttct ccatttttcg ctgtgtaatt gagttctaca
    42601 gcatttaatt taatcgtgat tccacgttca cgttccaaat ccatcgagtc taacagctga
    42661 tcttgcattt cgcgagacgt cacagtgtgc gtcatttcta aaatacgatc ggccaatgta
    42721 gatttcccat ggtcgatatg agcgatgatc gaaaaattac gaatctgctc ttggcgttct
    42781 ttcattttct ttatatccat agcgtctcct cttttcatat aatcagcact ttccattata
    42841 ccaacgaaaa gcagtaattt aaagagtttt taattagtca gctatagaag ttttttttgt
    42901 agaattttgc tatactgtta tcaagctaat aaatggagat gaaaaaatgg atcaaaaaga
    42961 ttttagagaa aatcttgaat taaaaccggt cactcaagaa catatcgatc aattcaatga
    43021 attgctttcc tatgtgttcc aagtgactga agcagacatc gaggaaagcg ggtttgagaa
    43081 taaacgagct tttatccgtt ccaaaaaacc gattttggaa gtatcgaaag tgttcggatg
    43141 gttccacgaa aataaactga tctctcaaat cgctatctat ccttgtgaag tcaatattca
    43201 cggtgcacgt tataaaatgg gtggtgtgac tggagttgga acttatccag aatatgctaa
    43261 ccatggattg atgcaagatc taattatcgt tgcattggat aatatgcgca agaataagca
    43321 atggatctct tatttgtatc cttacagtat cccctactat cggcgtaaag gatgggaaat
    43381 catgtctgat aaactttcct ttaaaatcag agatacacag ctacctaaac aaatcccagt
    43441 aagtggtatg gttgagcgat taccagttga tcatccagac gtattttccg tttatgacaa
    43501 atttgcccaa caaaaccatg gtgctttatt ccgcagtgat tttcattggg aagagtattg
    43561 gcgtttcgaa aatgaagatg agcgcacagc cgctgtctac tacgatagca accatgaacc
    43621 aagaggtgtt ctgttctact gggtagctga agaaatattt cacgtaaaag aaatgttcta
    43681 tcttgatcaa gaagctcgaa atggcttatg gaactttatt tccgcacatt tttccatgat
    43741 ctactgggta catggagata tttataaaaa tgagccttta gcatttttga ttgaagatag
    43801 tcagatcaaa gagcagatcg aaccatattt tatggctcgg atcgttgatg taaaagaatt
    43861 ccttcaacgg tttccgtttg ttggaacagc tgatgctttt catttcatca ttgaagatcc
    43921 tgtcgctcct tggaataatg gtgtcttcgc tttaacatgg gatgaacagg gacaagtccg
    43981 tgtcttaaat gaacctatag gaaaatccgt tcgactggat atccaaacat tgacttgctt
    44041 gatgatgaat tatcgccgtg cttcttattt ggcaagaatc gaacggttag aaacagatga
    44101 agaaacactg aagtcactag agcgtatcat tccaaacatg gaagcttact ttagcgatta
    44161 tttttgataa aaaggatgat gtttagatga aaatttattt tgccgcacca atgtttgcta
    44221 aaagtgattt gttatataac caacagttag ttaaagaaat cagagagctc tcttctgagc
    44281 tttcgatcta tcttcctcaa gaaaatgaag caatcaatga caaaactgct tatgcagaca
    44341 gtcgaatgat tgctcttgct gacacagaaa aagtgttggc tagtgattta atgattgctt
    44401 tactagatgg gctgacgatc gatgccgggg tagcatcgga aatcggtgtg gcttatgcga
    44461 aaggcatccc agtgatcggc ttatatactg atactcgaca gcaaggcgga acccacccga
    44521 aaaaaatcgc tgcactacaa gaaacagctg aaaatcaatt tcactacctg aacttatata
    44581 caataggttt gatcaaattg aacggaaaag tggtttcttc agaaattgag ttgctttcag
    44641 aagtaaaaag atttttagat ggagggactt tcagtgatta aagaaatcaa aaaggtgcaa
    44701 atagctttac ttgcttttgg tgtattcgtt gtctgctata atttttatga atttatcaca
    44761 caaaaatatt cgacttctca aggaatcaca tttatcgtgg aatctttatt agggattgca
    44821 ttgattttca tgccacaagt cattttgaaa gttttcaaac ttaaaatacc agcagcaatc
    44881 gttttgtttt actggttttt cttgttcatc tctgtctttt taggcacagg gatgcatttg
    44941 atcagtatca tctctttttg ggacaaaatc ttacatgcgg tgagtccaat ggtcctgaca
    45001 gctcttggct atggattgat tggttacttg atgaaagatg ctgagatatc aaaaaccagt
    45061 ccttggttgt tcctcttatt cggctttgcg tttgctggac tttgcggcgt gttttgggag
    45121 ttctgggaat tcttatgcga ccagttctta ggcatgaatc ttcaacgttt tgctgcttct
    45181 gatggcacac tgtttgtcgg acgagcagca ttgatggata cgatgggcga cttgctgaca
    45241 aatacgatag gtgctgcctt aatgggattg tttgcatggt ctcaaagtaa aaaagatgag
    45301 cgttactttg aaagttataa attagaaaaa gtgaaaaata cctaataaaa gaggttgtga
    45361 cagaagcggg cagcttcaag aaatttcggc ttatttttcg aagaaactac ttctggaaca
    45421 ctgtttattt gaaaaaagga ggtctgacac tagttgtgtc agaccccttt tttcttttat
    45481 agtctcaatg gaagattaga cgatttcttc tagctcttct gttttgaaat gaagttgtcc
    45541 atcaagtaaa gtaatcgtta cttttgattt aggcataaca tgtcctgcaa cgatttcttt
    45601 agctagtggt gtttctactt ccttagtgat aaatcgtttc aatggtcttg caccatatgc
    45661 tggttcataa gcattttcag caatccacgt tttggcttca tcactgattg tcagcaggat
    45721 ttcttgatgt tccagacgtt gtgccaattg cgccaccatt ttgtcaacga ttcctttcac
    45781 gttgtctagg ctcaatggtg taaataaaat cgtgtcgtcg attcggttca agaattctgg
    45841 tttgaagttt ccacgtaata gcgtgttgac ttgttcagcc actgcttctg gaatcgttcc
    45901 atcagcagtc acgccttcca gcagtaactg tgaaccgata ttgctggtca tgatcagaac
    45961 cgtatttttg aaatctacta ctcgcccttt tgaatcagtc aagcgtccgt catctaggac
    46021 ttgtaacaag atattgaaga catcgggatg cgctttttcg atttcatcca acaagacgat
    46081 tgtataagga tttcgtctga cagcttccgt taattgacca ccttcttcgt aacctacata
    46141 gcctggagga gctccgacta gacgagacac agcatgtttt tccatatatt cactcatatc
    46201 gatccgtacc atatgatctt ctgagtcaaa caagttctca gctaacgctt tcgctaattc
    46261 ggtttttccg acaccagttg gtcctaggaa aaggaaagaa cctagaggac gatttgggtc
    46321 ttgcaatcca gcccgtgaac gaattaccgc gtcactgacc gcatcaactg cttcatcttg
    46381 accaatcact cgtttatgaa gtgtttcatt caatttaatt agtttttctc gttcaccttc
    46441 tacaagtttc gttacgggga tacccgttaa tctgccaacg acttgagcaa tctcattttc
    46501 ggtaacggac tcttgaacca tcttaatctc gctgtctttt gctttagctt ctaattcctt
    46561 caattctttt tctaattgag gtatcgtacc atgacgcaat acagcagcgc gttctaaatc
    46621 atagttattt tctgcatctt ctaattcgtg ttttgcttta tcgatttcag cacgttttgc
    46681 tgaaacagaa ttgacttctt ctttttctgt ttcccactgc atcttcatcg catttgcttc
    46741 ttcacgaagt tcagctaatt cttcttgcaa atttttcaag cgttttttac ttgcatcatc
    46801 tgattctttt ttcagtgcag cttcttcgat ttccaactgc atcaaacgtc tagtaacttg
    46861 atctaattcc gttggcatag agttcatttc tacccgaatc gttgcactgg cttcatcgat
    46921 caaatcgatt gctttgtccg gtaagaaccg atcagtaata taacggtcag ataaagtagc
    46981 tgctgctact aatgcgttgt catggatgtt aacaccatgg tggatctcaa aacgttcttt
    47041 taatccacgc agaatactga tcgtatcttc cactgttggt tctttgacta ataccttttg
    47101 aaagcgacgt tccaacgctt tgtctttttc catatattga cggtactcat ctaaagttgt
    47161 ggcaccgatc aaatgtaatt caccgcgagc aagcattggt ttcaacagat ttccggcatc
    47221 catacttcct tctgtttttc ctgcccctac gatattgtgg atttcatcga tgaacaagag
    47281 gatacgtcca tcactttttt tgacttcttt caagactgct tttagtcttt cttcaaattc
    47341 accacggaat tttgctccag cgatcaatgc acccatatct aatgaaaaaa tcgttttatc
    47401 ttttaaattt tcaggcacat ctttgcgtac gatacgttga gcaagccctt caacgattgc
    47461 cgttttccct acaccgggtt ctcctatcag aacaggatta ttttttgttt ttcgtgaaag
    47521 aatacggatg acatcacgga tttcttcatc acgaccgatg attggatcca tttttccgct
    47581 tttgacttgc tgtactaaat caacgccgta tttttctaat gctttgtatt gttcttcttg
    47641 gttttgtgag gtcactcttt ctcctcctct catctcttcg atgtttttac gcaattcttt
    47701 ttcagataat ccgtttttat tcaaataaac agttaacgga taatttttta atttcatcaa
    47761 cgctaaaata acgacttccg ttgaaagaaa ctcgtcgccg aagctttcac gtatttggtc
    47821 tgcttcattc aataatcgaa agaaattctg gctgaggttt tgtccatatt ggacgtttcc
    47881 accagaaaca actggatact catccagtag acgatcaatt tcatgttcaa aagattcgac
    47941 atccaatccg gcatccgtat agaaatttcg accaaaatga ttagattgta aaaagatttt
    48001 ccatacatgg gcaatgtcga tatcttgatg ttttcgagtg accgcaatct gttgagcttc
    48061 agcaatcgct tcttgaagcg tcgtagtcat tttctcaata ttcatacagg tataccctcc
    48121 taattaaagg taagatcact tatttctttg atctttacaa aaactattat atcgctttgg
    48181 tcaattttgg tcaaaatata cacatagttt tttgactttt tttctcgact tatataaatc
    48241 ttaaaaaaac aaaattgatt gtatgtatat aaaaaaagag ccaaacaaac gtaaaattat
    48301 cttatccata acgtttttct ttgatttgat aaaaagggta gatcttataa aagacctacc
    48361 cttgattttc tttattctct ttttttactt ctattatttc ttctttgatc actcttcgcc
    48421 gttcagcaat cacatacaca aatccataga gaaatggcaa gataaaggaa ctgaaacgat
    48481 acagtaaaag cgaagaaact gcgtcaactg ttccaacaac tggtctgaat aataacaaat
    48541 agacaaattc aaaggaacca ataccagcag gcgtaggaat aacccctgaa agcactactg
    48601 caaagctgat aaacgaaatg gtcagtagaa aatctatttt aggatggttt tcaatcagaa
    48661 tcaaataagg aagtacatac caaaatacaa gttttaacat attccataga taaatccgca
    48721 atagcgcagt cctgtcttgg ataatggttt ggaccgtttc ccttaaagag tagatctgct
    48781 gattgcatgt atccacccat ttccgcaaac gctcactttt aaataactta ttcgataagc
    48841 tgacaaaaaa tatttgaaca ttcaagctga cggacatcgc caataaaaag gcaacaatca
    48901 cgatcgtcaa aaggatacca gcgatgataa accagatcat tgatggacca ttagaataaa
    48961 aaagagagaa ttggatgacc aagccagcta atgcataagt gatcactgcc agtttgtaca
    49021 taatcatatg gagtgctgtc acccctgctc cctgggatag cttcattcct tttttgttat
    49081 aaaaataaat ctccgagatc agcgttcctg taccaaacga aacgattcgg taaaacgcaa
    49141 tatagctaga ggtcaagaac ccatctttcg ttgtaaaatt cggcgcgaaa ggttcagcaa
    49201 tttctttgat tgagcgccct tcagcgattt ggtaaactgt ccctaatata acagccgctg
    49261 ccaaaacaac aacactggta gacagcaatt cggcaaagat atctgcaaat gattgattga
    49321 ttaaataata aataatggca aaaatcacaa tcagcaaaag cagattcaga atgattttag
    49381 ttttcgttcc tttagacgac atctcctgct ccttaatgga aaaaataaat gagaatcaaa
    49441 tcaacaagta cacctgcagc gaatcctata gtaaacttct ttttccgagt tttatgatgg
    49501 aaaacttttc gagagatcaa tcctcccaaa ccaccgccta acaggctgac aaatatcaaa
    49561 ttattctcag gaacacgcca gccgctagtt ctagcctgat gtttatcata ccccatcaga
    49621 caaaataagt aaaaattcac aatgaaaagg taaaaccaca aaggattgtg taacaataca
    49681 tccattactc ttcttccaac tttctgttaa ctactatttc taagcttttt cttctttctt
    49741 tggtgaataa actgttaatc cttttgatac aacagataat tcaactggaa gatcatctgt
    49801 cgtgtctcca tccgttcgag tgcccacaga tttttcctgc gcttggattt tcatgcgttt
    49861 ggctgtgaaa taagtaatgc cggggatcgt atagaatttg cctctcatga ttctaggcaa
    49921 ataaaaaata aatcggaaaa tatctaagga aggtacgatc gttacatgaa attttccatc
    49981 atctagggtc gctgagtcgt caaaatttgt aaaaccgccc acggagttag acatcgtgac
    50041 tgtcaacagt tgggattttc ctttccaatg ctcctcgtct gtttctaaat ccaaatgata
    50101 ttttttcttc ttcagcaata acttaaaaaa cttcttgata aagatccacg agccgtaacg
    50161 ctgtttttct tcttgactga tccaaactgc tgtatctgct aagattccga ttgtcagtgt
    50221 agagataatg acttcatcat tgacttgacc atagtctatt ttccgtacat tgccttccag
    50281 gatcacgtca gcagcttctt cttttttgag gggaatctca agaacacgtg caaggttgtt
    50341 gacagttcca cctggaagta atccgacatg gtattgagat aatgtttttt ggaacgcttg
    50401 gacgatatga tgaatcgtgc cgtctccacc tataattact aaagtatcag cttctatggc
    50461 ttctgctttc ttgactaatt ccgcatcatc aatcgatggg ccagtttcag ctagttctac
    50521 atataattct ggctgctttt cttttacata atcttgaaac cagcgtgcta atttctcacc
    50581 ctcatctttc cctgaacttt tgttataaaa aactagcagc ttttccattc tttacctcct
    50641 atttactctt caaaaaagag ggcgggacaa ccaattccat tgtcctgccc tttagcctta
    50701 gacagatgac attccatcat tgggacgaac gccttgtcat aagctgttct ttttcgattt
    50761 taactctttg tgttcaattc tgcaattttt acaatcacgt ctgttgcttt ttccattact
    50821 tgtaaagaaa caaattcgaa tcgtccgtgc atattttctc ctccggcaaa tagatttggc
    50881 gtcggaatac ccatgtaaga gatttttgaa ccatctgttc ctccacgaac tggttcgatc
    50941 actggagaga taccaagctc gatcattgct tgtttcgcta attccacgat gctcatatct
    51001 ttttcaatga tttctttcat gttgtaatat tgatcataca tatctacttt gattcgttct
    51061 tgatcaaatc gctgattcaa ctcttcttgg atatgtgtga tttgtgcttt gcgtgcttcg
    51121 aatttttcac gatcatgatc gcgaatgata taactcatag aagcttcttc aggattccca
    51181 tccaatgcca tcaaatggaa gaaaccttcg tatccttccg ttttttctgg aacttcatcg
    51241 gctggaagct gattatgaaa atcgattgct aactgtagag cattgatcat tgtatctttt
    51301 gccgtccctg gatgtacatt tttcccttgg atcgtaatat ttgcttgagc agcactaaac
    51361 gtttcatact gcaactcacc taaaggacca ccatcgactg tataagcaaa atctacatcg
    51421 aattgctcaa catcgaattt atccgctccg acaccgattt cttcatcagg accaaaagcc
    51481 actttgatgg taccgtgagg gatagaagga ttattgatca agatctccat tgcagtcatg
    51541 atttccgcaa tccctgattt gtcatctgct cccagtaatg tactgccatc tgttgtgatc
    51601 aatgtgtggc cttcataatt tttcaaattt ggaaaatctt ttgtattcaa tgtatagcgt
    51661 tcttccgcat ctagtacgat cgtagactcg ccatcatagt tttcaatgat ttgtggattg
    51721 actcctactg cattaaaatc tgctgtatcc atgtgggaaa taaatccaat ggaacgcact
    51781 tcatgatcaa cattgcttgg taatgttccc ataacgaatc cgttatcttc attatagaaa
    51841 acatcagcta agcctaactc ttctaattct tttttcaatt cttgcgcaaa agcaacttgt
    51901 gtctgagtcg atggagtcgt tttgcttgtt gcatcggagc gtgtttctgt tttgacatat
    51961 cgtaaaaaac gtggcaaaag attttcgtac atagtattct ctccttttaa ttaaattgaa
    52021 atgggtttgt atttgtttca gaaacgaaaa agttaatatc ccaattttct tcttgtttcc
    52081 aagattcaaa tttctcgata aatcgttgct tgcataacga ttcaatataa tgaccgggat
    52141 caattgcaat caacccagcg ctttgcatat catgagccgt atgataatag atatctcccg
    52201 tgatatagac atctgctctt tgggcgattg cttgcggata aaatttttca ccgcttccac
    52261 cgcaaatcgc aatgcgcttc acagaggatt ttgcattttt tggctggact attctcagtc
    52321 catctagttg gaacgcttct tttacttgtt ctacaaatgc ctctatagaa atttcttgcg
    52381 gcaattcacc tactcgtcct aacccaaaca tttcgactgg ttcatctata gcgaaaagat
    52441 cataagcagg ttcctcataa ggatgagctg accgcatggc ttgaatcact tgtttttcga
    52501 tagtttccgg caaaataacc tcaacttttg cctcttgaac ttgttctgtc ttccctactt
    52561 tcccaatcgc tggttgtgca ccagcttccg gagtaaatcg accgtgtcca atcgaggtaa
    52621 aacttgtacc ggtataatca ccttgtgtac cagcaccagc tgcagctaat acttcacgca
    52681 ttttctgtgc atgatccaca ggtacataaa cggccagttt tttataatga atctcatgag
    52741 tctttactaa ataactctcc acttcaatac cgagaagttc acaaaaccag tcattcagtc
    52801 catcccaaat aatatccatg ttcgtgtgtg ctgcatagac ggcaatatca tgtttcaaca
    52861 aatctgcata cattttttct tgtggctgat cagtaaccag ccgttttaca ggacgaaaga
    52921 ttggaggatg tttagcaatc agcaaatcga tttttttctt gattgcttct tcgaccactt
    52981 ctggacgaac gtctaatgtc atcattactc gttggattgg cttatccaat gttccgatat
    53041 gcagtccgac tgggtctcct tcttcagcta gccactgagg acaatagctt tcaaactttt
    53101 ggatgaaagt gcgtccgctg attgtcatgg ctttaaaacc tcctcaatca tttggatttc
    53161 ctgctcgatt tgtttttgac gtgcctcttg attagctgct tgtttgagct gttcacggat
    53221 agcttttctt tgttgaagct ctcttgtcca ttttgatttg aagatctcac ttttctcttc
    53281 aagcagaaat ggcccgaaca tcagctccat ttcattgtaa gtaactggtt tttgttcttt
    53341 ttcggctaca atgatttcat atattttttt attttcttca agtatttttt ctgattggat
    53401 tttatactga ttttcttgca gccaagatcg taatgtacgc tctccgatgt ttggctgaag
    53461 gatcaaacgt tcttgtccgc ttaagcgttg attcaacttg ccagcttcta ggatatctcg
    53521 gatcagtgaa cctcccatac ccgcaatcgt gacagctgta ataccatctt gtggctggat
    53581 agcatctaga ccatttgcaa ggcgtacggt gatacggtct tctaatccat cttttttgac
    53641 ttgcttacgt gctgattcat aaggaccttg aacgacttca ccagcaactg catattcgat
    53701 ttttcctctt aatatcaatg caacgggtaa gtaagcgtga tctgatccaa tgtctgctaa
    53761 acgagcggat tcagggacaa agtcacccac tgcggctaag cgctgagata aatctaaatg
    53821 gttcatagct tcactccttc tagataatta tagcattttc caaataaaat aaggagacta
    53881 ggaataaaaa a
//
LOCUS       DAZKKZ010000012        52949 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.012, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000012 DAZKKZ010000000
VERSION     DAZKKZ010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 52949)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 52949)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..52949
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.012"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(12..2183)
                     /gene="copB"
                     /locus_tag="ACG8LA_000761"
     CDS             complement(12..2183)
                     /gene="copB"
                     /locus_tag="ACG8LA_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper/silver-translocating P-type ATPase CopB"
                     /protein_id="HFQ0203084.1"
                     /translation="MNGNDMEKKHEHKKEVVNKESTESHEKQMEMKHDHSQMDHSMHM
                     GHNHGDIANSKQMDHSMHMDHEHGGMDHSMHMGNFKQKFWLSLILAIPIILFSPMMGM
                     EFPFQVTFPGSDWLVLILATILFIYGGQPFLSGAKMELKQKSPAMMTLIAMGITVAYI
                     YSVYSFIANLLNPHTHVMDFFWELATLIVIMLLGHWIEMNAVSNASNALQKLAELLPE
                     SVKRLTKDGKEETVSLKEVNEGDRLIVRSGDKMPTDGVILKGETIVDESAVTGESRGI
                     KKQANDKVIGGSINGDGTIEIEVTGTGENGYLAKVMEMVRKAQGEKSKLESLSDKVAK
                     WLFYVALIVGILAFIAWLFLTDLPNALERMVTVFIIACPHALGLAIPLVVARSTSIAA
                     KNGLLLKNRNALEQANDLDVIMLDKTGTLTEGKFTVTGVEVLDDAFNKNEILQYLGAL
                     EANANHPLAVGIMNYLKEHEIKPYQAENLKNLSGVGLEATVKKQQVKIVNEKEVERLG
                     LNVEQALLKPYQEQGNTISFLILENHLAAIVALGDVVKTEAKEFIRTLKERKITPVML
                     TGDNKNAAQAVADYLGIEEYYGGLLPDDKEAVVQKYLDQGKKVIMVGDGINDAPSLAR
                     ASIGMAIGAGTDIAIDSADVVLTNSDPKDILHFLDLAKQTRKKMIQNLWWGAGYNILA
                     IPLAAGILAPIGIILSPAVGAVLMSLSTVVVALNALTLKIK"
     gene            complement(2203..4389)
                     /locus_tag="ACG8LA_000762"
     CDS             complement(2203..4389)
                     /locus_tag="ACG8LA_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HFQ0203085.1"
                     /translation="MATAETKMDTFVITGMTCANCSARIEKELNGQPGVVNATVNLAT
                     EKASVKYEGTTTEKLIQSVENIGYGAILYDEAHKQKIAEEKQAYLKKMLFDLILSTVL
                     TLPLMLSMIAMMLGSHAAIVHFFHFPIVQLVLSAPVQFYVGARFYKGAYHAIKTKAPN
                     MDVLVAIGTSAAFALSIYNGFFRGHPQDLYFESSSMIITLILLGKYLEHTAKTKTGNA
                     IKQLMSLQTKTAQVIRNGKEETLAIEEVVVGDQLVIRPGEQIPADGRIISGSSAIDES
                     MLTGENLPVEKNPDDTLFGGTINTNGLLHMEVTQVGKQTVLAQIIQMVEDAQGSKAPI
                     QKIADRISGIFVPIVLVIAFITLIATGLITGDWQLALIHSVSVLVIACPCALGLATPT
                     AIMVGTGVGARNGILIKGGEALEAAAHLDSIVLDKTGTITEGKPKVTDLVGSKEVLSI
                     FYTLEQASEHPLGKAIVEYGKLQEAATYDMIDFTAHPGAGISGTINGVRYFAGTRKRL
                     IELNLSFDEYQEHALELEQQGKTVMFLADEKQVIGWIAVADQIKLEAKQAIKQLQNKG
                     LDVFMLTGDNKLAAETIGKQVGIDPKHIFAEVLPEDKAAYVEKLQKDGKKVGMAGDGI
                     NDAPALALADVGMAMGSGTDIAMETADVTLMNSSLASIAQTIELSRLTLRKIKQNLFW
                     AFVYNTIGIPFAALGFLNPIIAGGAMAFSSVSVLLNSLSLNRHMKK"
     gene            complement(4389..4598)
                     /gene="copZ"
                     /locus_tag="ACG8LA_000763"
     CDS             complement(4389..4598)
                     /gene="copZ"
                     /locus_tag="ACG8LA_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005507 - copper ion binding [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="copper chaperone CopZ"
                     /protein_id="HFQ0203086.1"
                     /translation="MKQQFSIEGMSCNHCAARVEETVSALDGVQKVKVNLKKANGTVK
                     FDETKVQSEKICQAINGLGYKAEVI"
     gene            complement(4611..5051)
                     /locus_tag="ACG8LA_000764"
     CDS             complement(4611..5051)
                     /locus_tag="ACG8LA_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0006825 - copper ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HFQ0203087.1"
                     /translation="MEKVKTPVKISDSEWEIMRVIWTLGQTTAQEITQILADSMDWKP
                     ATIKTLLGRLVKKEVIWTEQEGKKFIYHPAVSEMETVRSATENLFSHICAKRIGETIA
                     DLVEEATLTQEDINEILKQLEQKQPVDTIECNCIPGQCECKQHQ"
     gene            complement(5125..5664)
                     /locus_tag="ACG8LA_000765"
     CDS             complement(5125..5664)
                     /locus_tag="ACG8LA_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="topology modulation protein"
                     /protein_id="HFQ0203088.1"
                     /translation="MKIIVIGQSGSGKSTLARKIKEITDFPLLPLDLLWHTTDYSIQA
                     KKWFLQEQQSFMVSNPSWIVEGNYTSTLEERIKEADKIIWLKVPRYLAIYRVVWRSLK
                     RKINKKSRPDMPESFSEKLNREYLEFLSFIWHFEENNEPKIQQLIQVANARNKLIILK
                     TRREKQEFLTKLKIESKNN"
     gene            complement(6279..7745)
                     /locus_tag="ACG8LA_000766"
     CDS             complement(6279..7745)
                     /locus_tag="ACG8LA_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HFQ0203089.1"
                     /translation="MNNKQLRWFTVALIAFNMVWGMGNVVNNYAQQGVSVVTSWLLIL
                     AIYFIPYALIVGQLGSAFKDSKGGVSSWVENTTSNKRLAYYAAWTYWVVHIPYLAQKP
                     QAILIAGGWAVQGNGNIVNTMSVQMVAVISLIIFLAFLYLSTKGLSTLKVIGGLAGTA
                     MFVMSILFILLAVTAPFINPTMEFATPHMNQVKTYIPTFDFSYFTTVSMLVFAVGGAE
                     KISPYVNSTRNPAKEFPKGMIFLAAMVGICAVLGSVAMGMLFASDNIPKDLMANGAYS
                     AFQILGNYYGIGNSLMIIYALTNMIGQISALAFSIDAPLKILLADADPEFVPNWLRKR
                     NRKGTLVNGYLLTGILVGIIILLPIFGIKDMNELVKWLTNLNSVVMPMRYLWVFLAYM
                     MLNKAYKKFNSEYKFVKNPKIGFIFGAWCFAFTAFACILGMVPKVDYTADPKAWWFQL
                     FTNIITPIVLILLGMILPAIARRDKNKEITEPETVVQP"
     gene            complement(8056..10137)
                     /locus_tag="ACG8LA_000767"
     CDS             complement(8056..10137)
                     /locus_tag="ACG8LA_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042625 - ATPase-coupled ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HFQ0203090.1"
                     /translation="MKSYRLEGLDCANCAMKIEKGVQKINGVKEATVNFTSGKLTIDA
                     EEDHLATIEQEIKKVVKELEPDVKVTEIDKEKVSEHGNEKERNTLFRILFSLAGIALL
                     LLFDFNEPIRLIGYLLIYLLIGYDVVKKAVMNIVKGKIFDENFLMSVATIGAMLIGEY
                     PEAVAVMLFYQIGEYFQGLAVSHSRKSIRELMAIRPETAHVQTTEGLMTVNPEDVQIG
                     QFVLVKPGERVPLDGTIIEGESLVDTSALTGESVPKSVYVGETVLSGFINKNKPFLVQ
                     VEKSYENSTISKLLELVENASSKKAPAENFITKFARYYTPVVVGLAVLLAVLPPLVVS
                     GAAFSEWIYRALTFLVISCPCALVISVPLSFFGGIGGASKIGVLVKGSNYLELLAQTE
                     TVVFDKTGTLTKGDFSIQTIDTKIDPKIFMQYVASAEQFSTHPIAQSVLEGYAGPLLP
                     TANIQEFAGEGILAEVDGKQVLAGNHKLMERFEISFPSSQEIGTLLYLAIDQSYSGYL
                     VIADTLKEDAVDALVQLKKAGVKNTVMLTGDSKKIADHIGKQVGVDKIYSELLPEDKV
                     QRLEEILQRNNKKTAFVGDGINDAPVLARADVGIAMGGLGSDAAIEAADVVIMNDQPS
                     KIAEAIHLAKKTLKIVKQNIVFAIGIKILVLALGAFGFASMGDAVFADVGVTVLAVLN
                     AMRSLHVKNKR"
     gene            complement(10661..11020)
                     /locus_tag="ACG8LA_000768"
     CDS             complement(10661..11020)
                     /locus_tag="ACG8LA_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YccF domain-containing protein"
                     /protein_id="HFQ0203091.1"
                     /translation="MSCLGNVIWFIFGGLIGGLSWLAAGILWCITIIGIPIGMQCFKI
                     ASLSFAPFGKEVIYHQSGMSLIVNIIWLIVSGLPIALAHVVSGILLCITIIGIPFAKQ
                     SFKLARLALMPFGAEIV"
     gene            complement(11050..11391)
                     /locus_tag="ACG8LA_000769"
     CDS             complement(11050..11391)
                     /locus_tag="ACG8LA_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0203092.1"
                     /translation="MMEIRWAVKEDLPQINQLITDHPESFVKAKTAADLNDKNKLLLV
                     AVTKEKRIIGFAQADVQQSEERLDQRPSGKLIQHTLVTKENTEEIQKKFAEYLILEAK
                     KRRIKSFFAQF"
     gene            complement(11388..12062)
                     /locus_tag="ACG8LA_000770"
     CDS             complement(11388..12062)
                     /locus_tag="ACG8LA_000770"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HFQ0203093.1"
                     /translation="MKKRILFIGDSITDAGRDRAEATDLGKGYPLLIAGKLISQYPTM
                     EFECMNRGIGGDKIADLQVRWQEDCLALQPDYVSILIGINDTWHNTSDQAIFGTEKSA
                     QQFESVYRKLLNELQTVGICNIILMEPFVLPITDDRHGWRKDLDPKIQIVRKLAKEYG
                     ALLVPLDGIFNALGIVYGFSKYTREDGVHPTIGGHEIIAQSWIDAIAAVDFFSGDKNE
                     RKKSEK"
     gene            complement(13115..14413)
                     /gene="asnS"
                     /locus_tag="ACG8LA_000771"
     CDS             complement(13115..14413)
                     /gene="asnS"
                     /locus_tag="ACG8LA_000771"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004816 - asparagine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006421 - asparaginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HFQ0203094.1"
                     /translation="MEQIQIIDSKNHVGETVTIGAWVANKRSSGKIAFLQLRDGTAFF
                     QGVVVKSEVSEEVFQTAKNLHQETSVLVTGEIREDSRSKFGYEIGITNVEVVSESHDY
                     PITPKEHGTDFLMDHRHLWLRSSRQHAIMQIRNEIIRATYEFFNQHHFVKIDPPILTG
                     SAPEGTTDLFETNYFDQKAYLSQSGQLYMEAAAMAFGKVFSFGPTFRAEKSKTRRHLI
                     EFWMIEPEMAFTHQEESLEVQEQYVAFLVQNVLDHCEYALDVLGRDKEVLKTYTKLPF
                     PRITYDDAIELLKKNGFDDIEWGEDFGSPHETFIANSFEQPVFILNYPKAIKPFYMKP
                     HPTREDVVICADMIAPEGYGEIIGGSERATDYDFLLEQIRNHGLDEKEYSWYLDLRKY
                     GSVPHSGFGLGLERTVTWIAGIDHVREAIPFPRLLNRIYP"
     gene            complement(14453..15643)
                     /locus_tag="ACG8LA_000772"
     CDS             complement(14453..15643)
                     /locus_tag="ACG8LA_000772"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008483 - transaminase activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HFQ0203095.1"
                     /translation="MELSKRTKRLEPSVTLAAAAKAKALKAKGRDVLSLTVGEPDFAT
                     PENIQEAAIEAIRNGKASYYTPTAGIPELRQAIVDYLKKNYGLVYEPSQTVVTDGAKF
                     ALYTLFQTILDPQDEVIIPVPYWVSYGEQVKLAEGLPVFVKGEESNSWKVTVEQLEQA
                     RSEKTKAVIINSPSNPTGMIYSKNELQAIGEWAVKNDILIVADDIYGRLVYNGNEFTP
                     IATISEAIKNQTIIINGVSKTYAMTGWRIGYAVGNPVIINGMIAVASQSTSNPTAVSQ
                     YAAVEALKGEQDTVEEMRNAFEERLNTLYSLVAELPGVSLEKPQGAFYLFPNVKETLR
                     MCKYENVTQWVEDLLEETGVALVTGEGFGAPENVRMSYATDRATLEEAVRRIKQFIES
                     KSQN"
     gene            complement(15664..16191)
                     /locus_tag="ACG8LA_000773"
     CDS             complement(15664..16191)
                     /locus_tag="ACG8LA_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HFQ0203096.1"
                     /translation="MKIKERRPLKKKQTKEKTINRVLLGLIVFLLAVIVISSIFYLRS
                     SRPAVQAKKEAVEIAKKYANLEETDHFYWFTRKKTYFSLTGTNDKGKEIAVIIPKSGE
                     KVKVLDQTKGLTENEAKQTIAAAHPEIQIEKAALGMYDDQPVWEVVGKETNGKLNYYL
                     IGFESGDEVKTIKGI"
     gene            complement(16238..19027)
                     /locus_tag="ACG8LA_000774"
     CDS             complement(16238..19027)
                     /locus_tag="ACG8LA_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016818 - hydrolase activity, acting on
                     acid anhydrides, in phosphorus-containing anhydrides
                     [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helicase C-terminal domain-containing protein"
                     /protein_id="HFQ0203097.1"
                     /translation="MKPRTYAVVDIETTGTNPKEDRIIQFGCVMIESGRITSRFSIDI
                     HPGRKISKQIQHLTGITNQRVQKAPYFEDVAQTIYNLLADTIFVAHNIYFDYNFLNHE
                     LMRCGLPSLKIPGIDTVELAQIFLPTEPSFRLADLSESLGFIHENPHQADSDAEVTGQ
                     LLLLIEERMRKLPIITLEQIARLSRHTGMDTSRFIYHVIEEMKEKPEPLDPSLEIVDG
                     LALQKKEVELFTSVHYGERTYPRKKQAKEKMFGKTLMYRKEQNRLMNAVYDHFTKDES
                     KDLMIEAATGMGKTIGYLLPLSYLATPEKPAVISTVSLVLQQQIIEKDIPLLNQLLDQ
                     PIQPVIIKSYRHYIDLQRFKGTLVEPPEQKQYALYQMAVLVWLTQTKTGDLDELHLTN
                     LNHSFFADIAHRGIGFLARNQSFYEQDFVRFLQKKIRQSNFLIVNHAFLVQETQRKEP
                     LLPASPFLLIDEVHHLPEIAEKVNDKRLSINYFHKQIQQLEEPNQLFDRIQSYLPKEH
                     EALRWLSIYREELSALCEAQICMAEGLMSLVSGKQPNGQYPEEVMMTKEMLDQLPLES
                     GTAIDHLQLFYQEIQQLQSQMRLTFEIIQESWTNQMRIDLASLYSLFDQLDKQYLLMD
                     QWLEDWRDHLIHWFVPGNTAQQMIFHLHDFQAAMLPSTVWYPRYDRILYIGGTLKIGP
                     NRHYLSKRLGIEAAPLKVIASPYDYEKQARIYVPKEAPAVHQVSNQAYIDYLETALTG
                     LIEQEDRPILVLFTSHDVLQKVYQKMHLSMLEKGREILAQGFGGSREKLLKRFILSEK
                     SVLFGADSFWEGVDLPGDALQIVVVTRLPFDNPLRPMVKARNAYLESEGINPFYQESV
                     PKAALKLRQALGRLIRTETDRGVLLILDRRLVTAKYGARIIHALPKKVPIKELAMEEI
                     YQDIHEFLKKNEEGS"
     gene            19286..20587
                     /locus_tag="ACG8LA_000775"
     CDS             19286..20587
                     /locus_tag="ACG8LA_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HFQ0203098.1"
                     /translation="MPDLHHIKLLLGIKDKNIFITNVESKSIKNIKSLVVSATLSKEI
                     RRCPLCKQMNHEGMIVKNGKKKSLIQLNKCANQLTYLALAKQRYHCRGCHTYFTANTY
                     IVDRNCFIAKQVRYKILEELTEKQAMTTIAKHCGVSWSTVSRTLASLIPMTKVKRNWL
                     PRCLLMDEFRSLKNQVGPYSFSCMDGDTGKLLDILPSRKKKALVSYFMQFERRARLKV
                     KVIVTDMNVSYASLIKECFPKAKLVVDRFHIVKHLIRKFEDIRVRIMKSFDRNDPTQA
                     KYYRQLKALSRLLIKRQDKLVYDKWTKWRNFGWAYLTESEVVDRLLSISDELRIAYFY
                     YQEILQAFHDKEADTFFKLVRTMPNSVPKELHSIKKAFINYESGIRLALELPYSNAKI
                     ENLHTHIKALKRVAYGFRSFRKMKTRIFLLNNLITYESKNI"
     gene            complement(20675..20875)
                     /locus_tag="ACG8LA_000776"
     CDS             complement(20675..20875)
                     /locus_tag="ACG8LA_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HFQ0203099.1"
                     /translation="METGTVKWFNSEKGFGFITAENGNDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEEGQRGPQATNVTKA"
     gene            complement(21328..21648)
                     /locus_tag="ACG8LA_000777"
     CDS             complement(21328..21648)
                     /locus_tag="ACG8LA_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0203100.1"
                     /translation="MKKRLLWCLLSLSLSLTSQPVFAEETQRFPITGTRLYKNVYVQT
                     PDLDSAIPETEERSLQPRFGYFWYCPTCDYESCWHFLHSTAAAFAFTHTQKYDGHHPV
                     IYEV"
     gene            complement(22151..23269)
                     /locus_tag="ACG8LA_000778"
     CDS             complement(22151..23269)
                     /locus_tag="ACG8LA_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0203101.1"
                     /translation="MAKKDKELLSQLTSEGAKGPFVTIMLNTHVAHQDVEKDQIKFKN
                     FAKEAKKRFEKKYSEHDWSPFQEKIENLLGDPSFWRSATTSVAVIITADQTYIHRLSI
                     PVDDQYYVSDLPYLLAIIKNGQFNYSYYLLGLNRDSMKLYEVSNKQVKEVSLPEGAPV
                     DVVTALGSELTGGGLNFSSNGGGGARDGVTFHGVNPKDEEVEIDWVNYYQAVDTYLKD
                     SFENPEQWPIYLFALPENQTMFKKIAKNPYYCADVAISASPAQLSFRDIEEGAKKLSS
                     ELAAQESKEYNKLLDKKFIDQLVDIVPAAKEGKVSHLFIATSNLADGFGEDPETEYDR
                     RQVLNALADDVIINGGKVFILDQKDAPDEKSLTAILRY"
     gene            23502..23624
                     /locus_tag="ACG8LA_000779"
     CDS             23502..23624
                     /locus_tag="ACG8LA_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0203102.1"
                     /translation="MHLIMIFSLLSIISLFAFSASRLLDAETQPIPVKVRKNDR"
     gene            23740..25047
                     /locus_tag="ACG8LA_000780"
     CDS             23740..25047
                     /locus_tag="ACG8LA_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008800 - beta-lactamase activity
                     [Evidence IEA];
                     GO_process: GO:0030655 - beta-lactam antibiotic catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HFQ0203103.1"
                     /translation="MSIKKTRLVLLLASLILCLASFLPAVAVQAEDTFKVNAKAAFAV
                     DAQSGKILYDQDGEKTMGIASITKIIGLYIVLDQVKEGKLSWDDKVSISDYAENLSVT
                     PDLSNVPLHKENTYTVKELFDSAIIQSANASMVALAEKISGSEAKFTERMKEQLKDWG
                     IKDATIVNASGLNNSYLGENRPEGTGENDENQMSAQDVAIVARHLILDFPEILDVSST
                     TTQMFGENTQSPVEMVNWNWMLPGFVNYKEGVDGLKTGTTELAGACFVGTITKNDQRI
                     ITVVLNADGHAENPSARFNETARLMDYCYDNWSEKELGKANASIPSLKTIDVKDGKES
                     TVPVVLKSPVKVWVRNDMDTGKLTITPTLDKKQVTDNEIQAPMDKGTKIGTATITLAE
                     DKLGYLEDNNAPSTEIITDKTVEKANIFVIGWRRVAEFFGNLF"
     gene            25168..26367
                     /locus_tag="ACG8LA_000781"
     CDS             25168..26367
                     /locus_tag="ACG8LA_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HFQ0203104.1"
                     /translation="MNLTRDLIFLVLYLIGVFSIVYWRKQKKDPSLFFYSSTWTFAVI
                     LTYFVVLEIFYSTFYFLIPLVFFSIFAFSYFSEKRRLLNGLLFNVFLISFGIYLFVLL
                     YETQNIFLGGLIALITIPLLLVFLFGIYGLIVFLFWNGVTVLRRESHSLANLLTLILA
                     IFLTLFLVFDFFLLKYLPQWINALFFCIPLILIYLFIVFYNFLTVSFLYQFNRPRYNQ
                     DFIVVLGAGLINGETVSPLLAKRINKAIAFYWAQSRATLNPPILLMSGGQGADEKVPE
                     AMAMKQYAMEQGIPERDILVETNSTTTLENMRYSKEIMDQQMKGPYRAIFSSNNYHIF
                     RAGLYARQAKLKANGIGAKTAFYYLPNAFLREYIAILMMNKKRHMIICGLLFAGSAFL
                     SLITLLF"
     gene            complement(26394..27662)
                     /locus_tag="ACG8LA_000782"
     CDS             complement(26394..27662)
                     /locus_tag="ACG8LA_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="voltage-gated chloride channel family protein"
                     /protein_id="HFQ0203105.1"
                     /translation="MEKQLPSPVRILMYMLKWLVVTAILGVFMGSLSAFFLNSLTFVT
                     DIRLAHPWLFYLLPVSGALFAYLYAYHGGLSSRGNNLVIDQGNGGEEKIPLRLIPLTL
                     FGTITTHLFGGSVGREGTAVQMGGALADNIAHLFRLDKAEREILVISGISAGFSSVFG
                     TPLAGTLFGLEVLAIGKVRTEAIFPSFFAALFANFMTESYGVSHLHYQMGVIPEWSML
                     LFFKVFVAGIAFGLIGWVFSRSIVFLKARYAQWIPHPVWRNTIGGAVVVAAALILQTQ
                     RYLGLSLPILQESFNGQAHAYDFIGKLFFTVLSLGAGYQGGEVTPLFEIGATLGAVLA
                     PLLHVSVPFLAGLGFIGVFSGATNTPIACFVMGIELFGSQAAVYFFMICLISFMCSGN
                     SGIYSAQQVAVKKGILFLPIVKRIKEKNKV"
     regulatory      complement(27718..27784)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01734"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Fluoride riboswitches increase expression of
                     downstream genes that help mitigate the toxic effects of
                     very high levels of fluoride; They are found in a wide
                     variety of bacteria and archaea; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="fluoride"
                     /db_xref="RFAM:RF01734"
     gene            complement(27826..28473)
                     /locus_tag="ACG8LA_000783"
     CDS             complement(27826..28473)
                     /locus_tag="ACG8LA_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G-binding protein"
                     /protein_id="HFQ0203106.1"
                     /translation="MEQTMKPYQYFFIKREVEQLLNAYSSVNDSKTVQTVQALAAEKI
                     RDVLGYEPSEIDTFLTTVLDVKLTKTQAERALEELKQIVQPFMQPSKPQIEKLFRKVK
                     KLKQPAWNEIDLQAHTYIGWNDPGTQKKFMVYYEDGKLKGISGTLSPTINKGICAICQ
                     KTSNVSLFLSTTKAGSDGTYTKKGNYICHDSDQCNQQLTKLAPFYEFAERVKKER"
     gene            complement(28882..29385)
                     /locus_tag="ACG8LA_000784"
     CDS             complement(28882..29385)
                     /locus_tag="ACG8LA_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HFQ0203107.1"
                     /translation="MTEKWREDEEYMSYVEDLLETEAVKKLANYTQHVHSTRLEHSIS
                     VSYYSYLLAKKWGGNAKATARAGLLHDLFYYDWRTTKFDEGTHAYIHPRIAVKNAEKI
                     TDLSDLERDIILKHMWGATIAPPKYKEGYIVTFVDKYCAVKEAAQPMSASMRKRWQRY
                     FGKESSI"
     gene            complement(29508..30272)
                     /locus_tag="ACG8LA_000785"
     CDS             complement(29508..30272)
                     /locus_tag="ACG8LA_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0001510 - RNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrmH family RNA methyltransferase"
                     /protein_id="HFQ0203108.1"
                     /translation="MKEIQSAKNPRIKELKKLHKKKYREEKEEYLLEGFHLIEEAASS
                     DAEIKELFVTQRGMKEWGDWLAANKEISTFLVSDEVMDAVSDLPTPQGILAVMALTAE
                     GTPDFSGGWLLLDNVQDPGNVGTMIRTADAFDMAGVLLGKGTADIYSTKVLRSMQGSN
                     YHLPVLQKDLTEVIPLMKDKGFTVYGTELNEEAHALDKVEKSDNFAIIMGNEGQGVSQ
                     EILSLTDQNVYIPMKGNAESLNVGVAAGIVLYHFSL"
     gene            30380..30655
                     /locus_tag="ACG8LA_000786"
     CDS             30380..30655
                     /locus_tag="ACG8LA_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HFQ0203109.1"
                     /translation="MRKVKMNVQGRVQGVGFRYMTKMVADQLGVTGTVKNEDDGSVTI
                     EAIGNDDIIQKFIEEVKKSPSPSGRVQYVDVQEDPMIEERKKFDVVG"
     gene            31320..32270
                     /gene="yidC"
                     /locus_tag="ACG8LA_000787"
     CDS             31320..32270
                     /gene="yidC"
                     /locus_tag="ACG8LA_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0051205 - protein insertion into membrane
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HFQ0203110.1"
                     /translation="MNKWKNWLLGSGLVSILLFLSGCVRMDSNGNPDTSGIVYRVLVH
                     PMGQAITYLVENFNWSYGWAVIAMTVIVRIIILPLGISQSKKTMIQSEKMQALKPQVE
                     AAQQKLKAATTREEQMAAQAEMQQVYRENGLSMTGGIGCLPLLIQMPIFSALYFTARY
                     TEGIRESSFYGIDLGSPSMVLVVIAGVAYLLQGYISTIGIPEEQKKTMRTMLIVSPAM
                     IVFMSISAPAGVTLYWVVGGVFSCLQTFITNVMMKPRLKAQVAEELKQNPPKQVVTPR
                     KDVTESAKPADSKQATKQIKQPKNSTNNKGRNAGKQQKRK"
     gene            32374..33786
                     /locus_tag="ACG8LA_000788"
                     /pseudo
     CDS             32374..33786
                     /locus_tag="ACG8LA_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012008915.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182 family transposase"
     gene            complement(33772..34117)
                     /locus_tag="ACG8LA_000789"
                     /pseudo
     CDS             complement(33772..34117)
                     /locus_tag="ACG8LA_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737849.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            complement(34117..34245)
                     /locus_tag="ACG8LA_000790"
                     /pseudo
     CDS             complement(34117..34245)
                     /locus_tag="ACG8LA_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017769756.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
     gene            complement(34391..34591)
                     /locus_tag="ACG8LA_000791"
     CDS             complement(34391..34591)
                     /locus_tag="ACG8LA_000791"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0203111.1"
                     /translation="MAEMHDHLLHSICERTGLSEEEVNQKLMEISEAMNKGVDFSMNQ
                     LDDFLAQHMKDALASDAADSVE"
     gene            complement(34941..35288)
                     /locus_tag="ACG8LA_000792"
     CDS             complement(34941..35288)
                     /locus_tag="ACG8LA_000792"
                     /inference="COORDINATES: protein motif:HMM:NF019886.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma factor-like helix-turn-helix DNA-binding
                     protein"
                     /protein_id="HFQ0203112.1"
                     /translation="MDHLHDHDAENRLESNYARYLGGIEQTIEDSYTQDCMMSYTPDI
                     VEKIAPTDFKKMERKRLQEEIQKLTFNQRKVIEHYYFLNKNQQQIARDLRMSHAEITK
                     TLKRAFAVMKEVY"
     gene            complement(35482..35613)
                     /locus_tag="ACG8LA_000793"
     CDS             complement(35482..35613)
                     /locus_tag="ACG8LA_000793"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0203113.1"
                     /translation="MEDSKLPVTLIDVRRIINLGKQYMEGNQGQHQRRKAARLPLAE"
     gene            complement(35683..36060)
                     /locus_tag="ACG8LA_000794"
     CDS             complement(35683..36060)
                     /locus_tag="ACG8LA_000794"
                     /inference="COORDINATES: protein motif:HMM:NF025104.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0203114.1"
                     /translation="MFFLAFLYLYIANVKYFSKWPLLLFWIISCVLLLVKNAVFQFLL
                     KKIGSKSHTRVLVVENGNLAKEYGLAMLSDPDADANIIGYVKDRKKEDILLEEPGFAN
                     YGDGLAKLKYFGRISDVQDVIVK"
     gene            complement(36084..36407)
                     /locus_tag="ACG8LA_000795"
     CDS             complement(36084..36407)
                     /locus_tag="ACG8LA_000795"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0203115.1"
                     /translation="MIDRRDDSDRCWSIRYYYKGRINEIIKERFWNTVFDCIGDAASI
                     FVAYLLAMFICYHVLEAAPGINMLSVPYLMMAALYSILIADFLRIFRATNKTYFRKYQ
                     NGFLK"
     gene            complement(36469..36945)
                     /locus_tag="ACG8LA_000796"
     CDS             complement(36469..36945)
                     /locus_tag="ACG8LA_000796"
                     /inference="COORDINATES: protein motif:HMM:TIGR01670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KdsC family phosphatase"
                     /protein_id="HFQ0203116.1"
                     /translation="MSQIKFLVMDVDGTLTDGKIYMGECGEIMKAFNIKDGCAIHDIV
                     RAHNIEPIIITGRRSKILENRCKELGINILYQGIDNKIEKLLEITSDLSTVAYIGDDI
                     NDLSCMHPVKSAGGIVACPHDAVKKVLEISDFIAEHDGGNGAVREFVEWLVDTQNN"
     gene            complement(36962..37366)
                     /locus_tag="ACG8LA_000797"
     CDS             complement(36962..37366)
                     /locus_tag="ACG8LA_000797"
                     /inference="COORDINATES: protein motif:HMM:TIGR00022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HFQ0203117.1"
                     /translation="MSRSLYFLIKNSLLELEEGRYDLSNGIYLNVESYDIYRFEERMY
                     ESHLKYLDIQCILLGCEYIVVESISNLQIEVDYSADKDIVFYSNSIVGNCVLLEGGKL
                     LLLTPEDAHMPCIRVNESAKVKKAVFKISINY"
     gene            complement(37410..38375)
                     /locus_tag="ACG8LA_000798"
     CDS             complement(37410..38375)
                     /locus_tag="ACG8LA_000798"
                     /inference="COORDINATES: protein motif:HMM:TIGR00393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="KpsF/GutQ family sugar-phosphate isomerase"
                     /protein_id="HFQ0203118.1"
                     /translation="MDKIIEAKRVFDIEIEALKRTRDCLGKTFVRILDAIVNCEGKVI
                     ITGMGKPGHIAAKLAATFASLGTPAFRLHPAEAMHGDLGMVSEKDIVIAISYSGESDE
                     IVKILPNIKMIGATLIGITGNSKSTLATASDIVQILPEFEEACYLGLAPTSSATSVLC
                     YGDALAVVASGIYGFKDSDFGKFHPAGSLGKKLILKVSDLMSHGNEIPMVNSGTLLMD
                     AISVMSNKGLGIVSVIDQDGTLKGIITDGDLRRIIERKVDIYSVEIDDVMIANPKVFT
                     KDKLAVDALRFLKANSINILPIIDDEGMLVGTITWQQIVKAGIVA"
     gene            complement(38484..39260)
                     /gene="kdsA"
                     /locus_tag="ACG8LA_000799"
     CDS             complement(38484..39260)
                     /gene="kdsA"
                     /locus_tag="ACG8LA_000799"
                     /EC_number="2.5.1.55"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013102314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008676 - 3-deoxy-8-phosphooctulonate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-8-phosphooctulonate synthase"
                     /protein_id="HFQ0203119.1"
                     /translation="MNRLMLIAGPCVIESEENVMLIAKTIKEITEKLDIDYYFKASFD
                     KANRTSITSYRGPGIEEGLKILKKVKETYGLKICTDIHEPWQAEKAAEVCDILQIPAF
                     LCRQTDLLVAAAKTGKIINVKKAQFLAPWDMKNVINKLVEAGNSNIMLCERGTSFGYN
                     TLVVDMTSIVEMKKFGYPVVMDATHSVQKPGGKGDVTGGNRNNVEPLAKAAVATGADA
                     LFFEVHPDPDNALSDGPNMVLLDEFEGLLERVLKVYNAVR"
     gene            complement(39262..39999)
                     /gene="kdsB"
                     /locus_tag="ACG8LA_000800"
     CDS             complement(39262..39999)
                     /gene="kdsB"
                     /locus_tag="ACG8LA_000800"
                     /EC_number="2.7.7.38"
                     /inference="COORDINATES: protein motif:HMM:TIGR00466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008690 - 3-deoxy-manno-octulosonate
                     cytidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0009244 - lipopolysaccharide core region
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-manno-octulosonate cytidylyltransferase"
                     /protein_id="HFQ0203120.1"
                     /translation="MKTIAIIPSRYGSSRFPGKPLAMISSKPMIQWVYENVSKAAMLD
                     AVYVATDDKRIFDCVESFGGMALMTSDKHTCGTDRLAECAEILQLRDEDLVLNIQGDE
                     PLIKAEMIADLYSCFDNDEVYMGTLKKHIEVQEELDNPNVVKVINDVNDYAIYFSRFC
                     VPYERDGKNSLHFKHIGVYGYKTWFLKKYSTMPKTPLEVSESLEQLRVLESGFKIRVK
                     ETKYQTVGVDTPEQIQQVEDELRKEGL"
     gene            complement(39996..41423)
                     /locus_tag="ACG8LA_000801"
     CDS             complement(39996..41423)
                     /locus_tag="ACG8LA_000801"
                     /inference="COORDINATES: protein motif:HMM:NF024832.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140327 - flippase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flippase"
                     /protein_id="HFQ0203121.1"
                     /translation="MNRLIKNYAYNLCYQILVMILPIITTPYVSRVLKAEGVGEFNYS
                     YAIVSVAVIIAQLGTNMYGQREIAYVQNDKIRRSGVFWSIFVIRIISSFIVFPVYILI
                     SATLHSYTVLLISMSVYLVANLFDVSWFFQGMEDFKKTAIRSMVVKLIGLVLIFLLVK
                     NENDVVLYSVILAGTELLGNALLCCHIPKYVRRISIHDISITPHIRPILGLFLPTAAV
                     YIYTYVNKIILGIFSTDVQVGLYSQPEKIVKLLMTVITSLGAVMLPHIAVAVKENNID
                     RIRKEVLNAVSFVFCIGAPMVVGAIIIANTFIPWFLGDGYAKSVSLFQLLSPLILIIG
                     FASVVGQAVLIPMKRQRVYTFSIMTGAVINLVVNLALIPHLEAIGAAIGTIFAELTVT
                     AIQFYEVRNCIELKMASIITNVKNYLIGALIMGGVGGYVSSKLPNSVISTFITVILCI
                     LLYSILLICMKDKLLMDYLKRRKNR"
     gene            complement(41425..42738)
                     /locus_tag="ACG8LA_000802"
     CDS             complement(41425..42738)
                     /locus_tag="ACG8LA_000802"
                     /inference="COORDINATES: protein motif:HMM:TIGR04370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008755 - O antigen polymerase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polymerase"
                     /protein_id="HFQ0203122.1"
                     /translation="MIYQLLIVEFILILIMYILSNRCFISPAFIAIALFFLATCCVVY
                     NIEFWNVQYSKKTLWFITTGFLAMCIPEMYILFLDYLSKKRVDNYHQNQYKIEYVQIY
                     PSRQLNLIFALLSVVFFGVLLVEILRKGDYSTLGLYAIGAAKSDETQNSVIARFGISL
                     ITGLNLAYLYVFINNVIRCKERVLSNIKYLFPTLMYILCMFISGNRVFLVKLFAIVFL
                     IYIVMKSDVSPRGRVPVMQVVRKTLFVAVAILAVFYALRGITKVNSTAATREFSDYIT
                     YYIGSPVYMLDKYLQRYSPELNWGAKSLTSLVEMFGIEPEFKNAYIHVGGDSNFAGNE
                     FSWFQRPYSDFGWLGMLVFTFIVFWIFSWNIHIRINKEKNRRRRKYYILITAYFFYIP
                     VMSFYYCQMCFAFSITNIFSVVVACLLVREFTKRQDEIIFKIKEE"
     gene            complement(42739..43884)
                     /locus_tag="ACG8LA_000803"
     CDS             complement(42739..43884)
                     /locus_tag="ACG8LA_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009854067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 99-like
                     domain-containing protein"
                     /protein_id="HFQ0203123.1"
                     /translation="MKKARVLAFYLPQFHPVRENDIMWGKGFTEWTNVAKAKPLFKNH
                     YQPQIPADLGFYDLRISEVRKQQAEMAKKYGVEGFCYWHYWFGNGKRILELPFNEVLQ
                     SGEPDFPFCLGWANHSWSNKTWQKSKHFTKDVVFLEQTYPGDEDYILHFKSILPALKD
                     DRYIKVDGKPLFLVFAPDSIPDSAHFISLWNKLAKENGFEGIYFVARVTSVDNKFDLS
                     SMTDVAVHNRFQRFLDMGYDAINSDMQRYAELKISGYWKRGIKSIMRKTVGNFSANLY
                     PYDKIMENFYCEEEKRECVHPQLIPRLDRTPRSGKDARVYVDSTPEKFGNAIDRALSY
                     VQDKEPEHRILFLQAWNEWGEGNYMEPDLVFGCEYLEILRKKILGEE"
     gene            complement(43881..44687)
                     /locus_tag="ACG8LA_000804"
     CDS             complement(43881..44687)
                     /locus_tag="ACG8LA_000804"
                     /inference="COORDINATES: protein motif:HMM:NF014075.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-hydroxymethylpterin diphosphokinase MptE-like
                     protein"
                     /protein_id="HFQ0203124.1"
                     /translation="MVNIKIRKVIHRIPPILKLMRFVVDVQNKYFYDKFCKNTDNIQR
                     IEKLRNKFLGETCFIVGNGPSLTMEDLELIKDKDCFAANLIFKIFDKTQWRPKYYFIQ
                     DRYADTGNELDDIDLEYMFIGDYYWRVRGMHNPNAICIHSEQSVGGKNIKFSEDISKS
                     IVSHETVTYSMIQAAVYMGYKKIYLLGMDHSYALTYNADGTVSEDKTIRSHFFEDKNA
                     NEVIASIVGMNQAYIRAREFCESNNIKIYNATRGGKLNWFDRITLEEAVK"
     gene            complement(44746..44913)
                     /locus_tag="ACG8LA_000805"
                     /pseudo
     CDS             complement(44746..44913)
                     /locus_tag="ACG8LA_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016396235.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
     gene            complement(45282..45416)
                     /locus_tag="ACG8LA_000806"
     CDS             complement(45282..45416)
                     /locus_tag="ACG8LA_000806"
                     /inference="COORDINATES: protein motif:HMM:NF013621.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylyltransferase/cytidyltransferase family
                     protein"
                     /protein_id="HFQ0203125.1"
                     /translation="MKEKVIEYTTGVYDMFHIGHLNVMRNAKAQCDFLIVGVSTDEPV
                     "
     gene            complement(45757..46890)
                     /locus_tag="ACG8LA_000807"
     CDS             complement(45757..46890)
                     /locus_tag="ACG8LA_000807"
                     /inference="COORDINATES: protein motif:HMM:NF012744.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HFQ0203126.1"
                     /translation="MRQKIRVLHIAQAAGGVDCYIRMLLKYLDKEKFENILICSQDFC
                     ETDYANLVLSFKQIKLTREIDLNDLKAIVIIRKLIKKYNPDIVYAHSSKAGAITRVAK
                     IGLKNYCVYNPHGWAFNMRCSVKKKMLYTAIEKIAALFCDKIICISDAEKQSALKKRI
                     CCEDKLQVIFNGVDIEAYRNKAHGEVKRESLNIPQDAFVVGMVGRISPQKAPEIFIKM
                     ARLVKNKIPEAHFIIVGNGEQKALIEKYAAEHGFLESLHITGWVNNSISYIELFDVAC
                     LLSRWEGFGLALPEYMMVGKPIIATNIDAIPNLISNGKNGLLVPVDDETAACEAVFKI
                     FSDKAMAARLTSEATSVVLEKYNSKRVASEHAVLFEMLVKKRG"
     gene            complement(47027..47227)
                     /locus_tag="ACG8LA_000808"
     CDS             complement(47027..47227)
                     /locus_tag="ACG8LA_000808"
                     /inference="COORDINATES: protein motif:HMM:NF014453.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HFQ0203127.1"
                     /translation="MFKFYKFRFVFVDDESPQIWNIFKEDMNIVGPKSGLLRKMKQYG
                     GYERQQLYVQPDLSYYWQIALN"
     gene            complement(47823..48512)
                     /locus_tag="ACG8LA_000809"
     CDS             complement(47823..48512)
                     /locus_tag="ACG8LA_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HFQ0203128.1"
                     /translation="MESEDLLSRISKVHPNQVWLDKEKVEKRYIYLFFKRMIDIVGSI
                     IGLILASPLMFYAAYRIRKEEPGSPIFFSHTRVGKNGKTFKMYKFRSMCLDAEEKLEE
                     LLDQNEIEGAMFKMKEDPRVTQIGKIIRAKSIDELPQLWNVLKGDMSLVGPRPPLERE
                     VAEYTRYDLQRLYVKPGCSGLWQVSGRNDVSFHAMVDLDLEYITNQSLLNDFKLIIKT
                     IWIVIKPNGAY"
     gene            complement(48566..49330)
                     /locus_tag="ACG8LA_000810"
     CDS             complement(48566..49330)
                     /locus_tag="ACG8LA_000810"
                     /EC_number="3.1.3.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA];
                     GO_function: GO:0030145 - manganese ion binding [Evidence
                     IEA];
                     GO_process: GO:0045227 - capsule polysaccharide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CpsB/CapC family capsule biosynthesis tyrosine
                     phosphatase"
                     /protein_id="HFQ0203129.1"
                     /translation="MIDLHCHILPGIDDGAENLEASIVMAEKAIQQGITHILCTPHHN
                     NGKYSNEKSQVISLVASLQAELEKRQLPLTLLEGQEVRITGTLIEDIQRDEILFTDLD
                     DTYLLIEFPTLEVPLYAEQLFFELLELGKTPVIVHPERNAHFREDPNHLLPFLDMGCL
                     AQLTAPSYVGVFGKDIQKTAKTMVKHNLVQMAASDAHGVSKRTFYLKECYEQIAKDFG
                     KEKVVQMKQVAKDLINGDEISYPIYEEVKKKKFGLF"
     gene            complement(49358..50056)
                     /locus_tag="ACG8LA_000811"
     CDS             complement(49358..50056)
                     /locus_tag="ACG8LA_000811"
                     /EC_number="2.7.10.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004713 - protein tyrosine kinase activity
                     [Evidence IEA];
                     GO_function: GO:0004715 - non-membrane spanning protein
                     tyrosine kinase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CpsD/CapB family tyrosine-protein kinase"
                     /protein_id="HFQ0203130.1"
                     /translation="MARTQKQKATPTHAVSLITLTNPSSPIAEQYRTIRTNIQFASTT
                     GQQIKTIVVTSSGPGEGKSTTASNIAVVFAKSGQRVLLVDADLRKPVIYKTFQLNNAS
                     GLSTALSSSGSVADVIQRAPVENLSILPSGPKPPNPSELLSSPRMDQILAEARQLFDV
                     VIFDMPPIVAVTDAQIMSSKTDGTLLVVRENTSRKESLTKAKELLEMVQARVLGVVYN
                     GAEHSKDDGYYYGN"
     gene            complement(50069..50848)
                     /locus_tag="ACG8LA_000812"
     CDS             complement(50069..50848)
                     /locus_tag="ACG8LA_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009103 - lipopolysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Wzz/FepE/Etk N-terminal domain-containing
                     protein"
                     /protein_id="HFQ0203131.1"
                     /translation="MEETISLEEIFETLRKHLITIIISMFAGLAISGIVTFFILTPKY
                     SSQAQLIVTLPQSDTANVNDVNTNLQMINTYKDMIVSDLVLNEVQERLKTEDNVKMTP
                     EQIKDAISINQSENSQMFSIQAISTSAMTAQQIANTTSQVFQENAKDVMNVDKISIVS
                     GAVANTTPISPNNKLNLVIGLMLGMMVGVVLAFLFELLDRTVKDEKYVTDTLGFPILG
                     TVPEMSEKELKAGIRKKGLAPTRPKVTNDKTASSRRSRSRV"
     gene            complement(50864..51808)
                     /locus_tag="ACG8LA_000813"
     CDS             complement(50864..51808)
                     /locus_tag="ACG8LA_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HFQ0203132.1"
                     /translation="MARRRRKSRGKKIFLIILAVLIVLVLAIVGVGAKLYLDLSHSIE
                     KTYESVERTQGERTKPVDLNKQESFSVLLMGIDTGDLGRVDQGRSDTMMVATVSPEDK
                     QTTIVSIPRDTYVDIVGRDTKDKINHAYAFGGAAMAMDTVQKYVDIPIDHYVSINMKG
                     LKELVDAVGGIEVNNDLTFSQDGYDFPIGKITLNGVQALSYSRMRYEDPNGDYGRQGR
                     QRKIVEGVAKKVLSLNGVSNYQSILNALESNMKTDMSFDEMKKIALDYREAFDTIKQD
                     QMQGEGFMQDDISYQKVNDNELDRVKKELKEQMNLENK"
     gene            complement(51845..52621)
                     /locus_tag="ACG8LA_000814"
     CDS             complement(51845..52621)
                     /locus_tag="ACG8LA_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0203133.1"
                     /translation="MEKPFVKLLATVAVGTGAIVICLFGYHFNNQRQHHQRINYAESA
                     ITNQKDTVTSLSKEVDKLYSTKEKIFLNPEITEETVSNLSHKLSSIKLSADDYDIKES
                     ELPKEAAAIQEEKKAVLTQLEDAESKLKIQTAVNDLFTKNVSNWQQAVDDVVIKEKVT
                     SADVARVRENMSFFKDSPWKTVVMQYLGFADTQIAQVTQLDQLFDTMLKDGQVTATAT
                     YDQYLTVLSQIEQIRNEKIRAAYATKAQTVAQQMGYSNIS"
BASE COUNT        15551 a        11354 c         8819 g        17225 t
ORIGIN      
        1 ttttttcatt attatttgat tttcaatgtc aaagcattta gagctacaac taccgtactt
       61 aacgacatca agacagcacc aactgctgga cttaatatga taccaattgg cgcaagaatt
      121 ccggctgcta gcggaattgc aagaatattg taacctgccc cccaccagag gttctggatc
      181 attttctttc gcgtttgctt ggctagatca agaaaatgca aaatatcttt tggatcgctg
      241 tttgtcaata cgacatccgc agaatcgatt gcgatatctg tccctgcacc gattgccatc
      301 ccgattgaag cacgggctaa acttggcgca tcattgatcc catcacccac catgattact
      361 tttttccctt ggtcaaggta tttctggaca acagcttctt tatcatctgg taataaaccg
      421 ccataatatt cttcgatccc taaataatct gctactgctt gggcagcgtt tttattgtca
      481 ccagtaagca tgacaggagt gatttttctt tctttcaatg ttcggataaa ttcttttgct
      541 tctgttttta ctacgtcacc taaagcaacg attgcagcta gatgattttc taaaatcagg
      601 aagctgatgg tatttccttg ttcttggtaa ggtttcaata atgcttgttc tacgtttaat
      661 ccgagacgct caacttcttt ttcattaact attttcactt gttgtttttt gactgttgcc
      721 tctagcccga ctcctgaaag attttttaga ttttcagctt gataaggctt gatttcatgt
      781 tctttcaaat aattcataat gccaacagcc aatggatgat tggcattcgc ttccaaggct
      841 cctagatatt gaaggatttc atttttattg aacgcatcat caagtacttc gacacccgtt
      901 acagtaaatt ttccttctgt tagtgttcct gttttgtcca gcatgatcac atctagatca
      961 ttggcttgct ccagtgcatt gcggtttttc aaaagtaatc cgtttttagc tgctattgat
     1021 gtggagcgag caacaactaa tgggatagct aaacctagag catgaggaca ggcgatgata
     1081 aagactgtta ccatacgttc taatgcatta ggaagatctg tcaagaacaa ccaggcgatg
     1141 aatgccagga tacccacaat taatgcgaca taaaacagcc attttgccac tttgtcagat
     1201 aatgactcta gcttggattt ttctccttgt gcttttcgca ccatttccat aaccttcgct
     1261 agataaccat tttcaccagt tccagttact tcgatttcga tcgttccatc cccattgata
     1321 gaaccgccaa tcactttgtc attggcttgt tttttgattc ctcttgattc gccagtcaca
     1381 gctgattcgt caacaattgt ttcacctttc aagattacac catctgttgg cattttatca
     1441 ccagaccgga cgatcaaacg atcaccttcg tttacttctt tcaatgaaac tgtctcttct
     1501 tttccatctt tcgtcaagcg tttcactgat tctggcagta attctgctag tttttgtaaa
     1561 gcattgctgg cattcgacac agcattcatt tcaatccagt gacctagtag cataataacg
     1621 atcaaagtag ccaattccca gaagaaatcc atgacgtgtg tatgtggatt gagcagattt
     1681 gcgataaacg aatagacact ataaatatat gcaactgtaa tccccatcgc gatcagtgtc
     1741 atcatagcag gacttttttg tttcaattcc atcttagctc cacttaaaaa tggctgaccg
     1801 ccatagataa atagtatagt tgctaagatc aatacgagcc aatcagaacc aggaaacgtt
     1861 acttgaaatg gaaattccat tcccatcatt ggtgaaaaaa gaatgattgg gatagctagg
     1921 ataagcgata gccaaaattt ttgtttgaaa ttccccatgt gcatggaatg atccatgccg
     1981 ccgtgttcgt gatccatgtg catcgaatgg tccatttgtt tgctgtttgc tatatctcca
     2041 tggttatgtc ccatgtgcat ggaatgatcc atctgactat ggtcatgttt catctccatc
     2101 tgtttttcat gagattctgt actttctttg tttactactt cttttttatg ctcatgtttt
     2161 ttctccatat cgttcccatt catttttact ccatcccttc tcttactttt tcatgtgtcg
     2221 atttaagctc agggagttca acaatacact gacggaacta aacgccatcg ctcctcctgc
     2281 aatgattgga ttcaaaaagc ctagtgcggc aaaaggaata ccaatcgtat tatagacaaa
     2341 agcccagaaa agattttgtt tgatttttct caatgtcaac ctagacaact cgattgtttg
     2401 tgcaatggat gccaaactgc tattcatcag cgtcacatcg gctgtttcca tcgcaatgtc
     2461 cgttccactt cccattgcca taccgacatc agctaatgct aaggccggtg catcattgat
     2521 tccatcgcct gccataccga cttttttgcc atctttctga agtttttcta cgtaggctgc
     2581 tttatcctct ggaagtactt cagcaaagat atgctttgga tcaataccaa cttgtttacc
     2641 aatcgtttcg gctgccagtt tgttgtctcc tgtcagcata aaaacatcta atcctttatt
     2701 ctggagctgc ttgattgctt gtttggcttc tagtttgatt tgatcagcca cggcaatcca
     2761 cccgatcact tgcttttcat cagctaaaaa catgactgtt tttccctgct gttctaattc
     2821 taacgcgtgt tcttggtatt catcaaatga taggttcaat tcaattaatc gtttacgtgt
     2881 acccgcaaaa tagcgtactc cattaatcgt accgctgatc ccagcacctg ggtgggctgt
     2941 aaaatcaatc atatcgtatg ttgctgcttc ttgcagtttt ccgtattcca cgattgcttt
     3001 acctagtgga tgttcagaag cttgttctaa agtataaaaa atagatagga cttcttttga
     3061 accgactaga tctgtaactt tgggctttcc ttctgtaatc gttccagttt tatccaaaac
     3121 aatgctgtct aagtgagcag ctgcttctaa tgcttctccg cctttaatta aaattccatt
     3181 tcgtgcacca acacccgttc ctaccataat agctgttggg gtcgctaaac ctaatgcaca
     3241 tggacacgca atgactaata cagagacact atggatcaat gcgagttgcc aatcaccagt
     3301 gatcaaacct gtagctatga gcgtgataaa cgcgatgact aatacgatcg gaacaaaaat
     3361 ccctgagatc cgatctgcga ttttttggat tggggctttg ctcccttgag catcttccac
     3421 catttgaatg atttgcgcta atactgtctg cttgccgact tgtgtgactt ccatgtgtag
     3481 cagaccattc gtattgattg tcccgccaaa aagcgtgtca tccggattct tttctacagg
     3541 aagattttca ccagtaagca tactttcatc tatcgcactg cttcctgaaa taattcgacc
     3601 atctgctgga atctgctcac caggacggat gactagttga tcaccaacga ctacttcttc
     3661 aatcgctaac gtttcttctt tcccgtttct tatcacttgg gcggtttttg tttgaagaga
     3721 catcaattgt ttgattgcat tacctgtttt cgtttttgct gtatgttcca aatatttgcc
     3781 gagcaaaatc agcgtgatga tcatactgct gctttcaaaa taaagatctt gggggtgtcc
     3841 acggaaaaat ccgttgtaaa tgctcaatgc aaaggcagcc gatgttccaa ttgctaccaa
     3901 tacatccata tttggtgctt tcgtcttgat tgcatggtac gcacctttat aaaaacgagc
     3961 accgacataa aattggacag gagcagacag cactaactgg acgattggaa aatgaaaaaa
     4021 gtgaacaatc gccgcatggc ttcctaacat catagcaatc attgacaaca tcaacggcaa
     4081 agtcaaaacc gtactcaata taagatcgaa tagcattttt ttcaaatacg cttgcttttc
     4141 ttctgcaatt ttttgtttgt gggcttcatc gtacaaaatt gcaccataac cgatgttttc
     4201 tacgctttgg attaattttt cagtggtcgt cccttcatat ttgacacttg ctttttcagt
     4261 ggccaagttg actgtggcat tgaccacacc aggttgtccg ttcagctctt tttcgatcct
     4321 agcagaacaa tttgcacaag tcatacctgt aatgacgaac gtatccattt tggtttctgc
     4381 tgttgccatc aaatcacctc tgctttataa cccaatccat tgattgcttg acaaatcttt
     4441 tcggattgaa cttttgtttc atcaaacttg accgtaccgt ttgctttttt caaatttact
     4501 ttcacttttt gcacgccgtc aagtgcgctt actgtttctt ctactcttgc tgcacaatga
     4561 ttgcagctca taccttcgat tgaaaattgt tgtttcattt tttcttcctc ctattgatgt
     4621 tgtttacatt cacattgacc tgggatacag ttacattcga tcgtatctac tggttgcttt
     4681 tgttccagtt gtttcaaaat ctcattgata tcttcttgag tcaaagtggc ttcttctact
     4741 agatccgcaa tcgtctctcc aatccttttt gcacagatat gggaaaaaag attttccgtc
     4801 gcactgcgaa ctgtttccat ctccgagaca gctggatgat aaatgaattt ttttccttct
     4861 tgttctgtcc agatcacttc tttttttacc aaacgtccca gcaaagtttt gatcgttgct
     4921 ggtttccaat ccatcgaatc agctaagatc tgcgtgattt cttgggctgt cgtctgtcca
     4981 agtgtccaaa taacacgcat gatctcccac tctgaatcac tgatctttac tggcgttttg
     5041 actttttcca tttatttcac acctttcgtt tacaaatgta atcattagct tatgaataca
     5101 gattacgctt gtaaacaaaa actgtcaatt atttttgctc tctattttca atttagttaa
     5161 aaattcttgt ttctctcgtc ttgttttaag gatgatcagt ttatttcttg cattagctac
     5221 ttggatcagc tgctgtattt tcggttcatt gttttcttca aaatgccaga taaaagataa
     5281 aaattctaag tattccctgt ttagtttctc tgaaaatgat tcaggcatat ctggccgaga
     5341 ttttttgttt atctttcttt ttagagaacg ccaaactact cggtagatgg cgagataacg
     5401 cggcacttta agccaaatga tcttatctgc ttctttaatc ctttcctcta atgtagaagt
     5461 ataatttcct tcaacaatcc atgacggatt agataccata aacgattgct gttcttgcaa
     5521 aaaccacttt tttgcctgaa tactgtagtc tgttgtatgc cataaaaggt ctagcggcag
     5581 tagcggaaag tcggtgattt ctttgatctt ccttgcgagg gtcgattttc ccgacccact
     5641 ttgtccaatc acgatgatct tcattcttct ccctcacttc tctttggaat ttggttcgat
     5701 cataccactt ataacgccgc aaaaaaacaa gggactgtga caaaagtcgt gtcaaagtcc
     5761 cttgtttcga ataaatggtg ttcaatcagc tgaccttcag cattaactca aaaaacggca
     5821 aaatatgagg agctattttt tcgtttgttc ctctaatact caggtcaaat cgctgatttt
     5881 acaacctctt ccttaaacgg tgttctcctg ccaacacctc ggtcacaagg cacaatagtc
     5941 aacaaacatg agaagttgtt ttttgaaatt gctccttgtg actcggagtt aaacggcagg
     6001 ctcactacct ctttcttaaa cggtgttcaa aagcttgcat ctgcggtaat aagcccagca
     6061 aaacgaaaaa tatgaggggc tatttttgtt tggctgttct tattacttga tgcaggacag
     6121 ctttttcaca acctctgatt cacggtgttc cagaagtagc ttctgcgaaa aacaagccga
     6181 aacttcacaa aaatttgaga agcaattttc gtaaattcct tcttatttct tgaagctgac
     6241 cacttctgtc acaacctctt gtaacaagta tttctatttt aaggctgaac cactgtttct
     6301 ggttcagtga tttctttgtt tttgtctcga cgagcaattg ctggcaagat catacctaat
     6361 aagatcaaga caattggtgt gatgatattc gtgaataatt ggaaccacca tgctttagga
     6421 tcagcagtat aatctacttt tggcaccatt cctaggatac atgcaaacgc agtgaaggca
     6481 aagcaccaag caccaaagat aaaaccgatt tttggatttt taacaaattt atattcagaa
     6541 ttgaatttct tataagcttt attcaacatc atatatgcca agaacaccca taggtaacgc
     6601 attggcatga caactgagtt caagttcgtc aaccatttta ctaattcatt catatctttg
     6661 ataccaaaga tcggcaacaa aataatgatt cctactagta tacctgtcag aagataacca
     6721 ttcaccaatg tacctttacg attacgttta cgtagccagt ttggtacaaa ttctggatcc
     6781 gcatctgcta acaagatttt tagtggtgca tcaattgaaa aggctaatgc ggagatttgt
     6841 ccaatcatgt ttgtcaatgc gtaaatgatc atcaatgagt taccgatacc atagtaatta
     6901 cctaaaattt gaaaagcact gtatgcccca tttgccatca agtctttagg aatattatcg
     6961 ctagcaaaca gcatacccat tgcgactgag cctaatacag cacaaatccc taccattgct
     7021 gctaagaaga tcatcccttt aggaaattcc tttgcaggat ttcttgtaga gttgacataa
     7081 ggggatattt tttccgctcc tccaactgca aatactagca tcgaaacggt tgtgaaataa
     7141 ctgaaatcaa atgttggaat atatgttttc acttgattca tatgtggtgt ggcaaattcc
     7201 atcgttggat tgatgaacgg tgccgttaca gctaaaagaa taaataagat cgacatgacg
     7261 aacatcgctg ttccggccag tccgccaatc actttcaaag tagaaagtcc ttttgttgat
     7321 aaatataaaa aggcaagaaa tataataagt gaaataactg ctaccatttg tactgacatc
     7381 gtatttacga tatttccatt tccttggact gcccaaccgc cagcaatcag gattgcttga
     7441 ggcttttgtg ccaaataagg aatatggacg acccagtaag tccaagcggc atagtatgcc
     7501 agtcgtttat tagatgtcgt attttcgacc catgaactga cgcctccttt actatccttg
     7561 aaggctgacc ctaattgtcc aacgatcaat gcgtatggaa taaaataaat ggccaaaatc
     7621 aatagccaag aggtgacaac tgatactcct tgctgagcat agttattaac tacattcccc
     7681 atgccccaaa ccatgttaaa tgcaattaac gcaacagtaa accagcgtaa ttgtttgttg
     7741 ttcattcgtt ctctccttta tgataaaaat ttgttatcca gatgtaatca tattcaattt
     7801 ttaacaaact tacaagacag tgttatttta tgtgtgtatt cttttattta atacacatct
     7861 ttttttcata ttttttccat caaaaaaata agttattttc ttttatttca tttaccttat
     7921 tgaatttcaa gctattttga attttctgca aaattaaaaa cattagttat tttataatcc
     7981 tatctatttt ctttacattt ttcattaaga aaaggatata aaaaaaagag gacgttcatt
     8041 cgtcctcttc attgatcaac gtttattttt tacatgcaag cttcgcatgg cattcaaaac
     8101 agctaatact gtcaccccaa catctgcaaa tactgcatct cccattgatg caaaaccaaa
     8161 agcacctaag gcaagtacca aaatttttat cccaatagca aagacaatgt tctgtttgac
     8221 gattttcaat gttttctttg ctaaatggat tgcttctgca atcttcgatg gttgatcatt
     8281 catgatgact acatctgctg cttcaattgc agcatcgctt cccaatccac ccattgcgat
     8341 tcctacatct gctcttgcta gcaccggtgc atcgttgatt ccatctccga caaatgcggt
     8401 ctttttattg tttctttgta agatttcctc taaccgctgc actttatctt ctggaagcaa
     8461 ttcgctatat atcttgtcca cgcctacttg cttcccgata tgatcagcaa tttttttcga
     8521 atcgcccgtc aacatgactg tgttcttcac accagccttt tttaattgaa ccaatgcgtc
     8581 tacggcatct tctttcaagg tatctgcaat aacaagataa ccactgtaac tttgatcgat
     8641 cgctagataa agcaatgtac cgatttcttg acttgaagga aaagagattt caaatctttc
     8701 catcaatttg tgattacctg ctaatacttg tttgccatca acttcagcta agatcccttc
     8761 acctgcaaat tcttggatat tagctgttgg taaaagcgga cctgcgtagc cttctaaaac
     8821 agattgagca atcggatgtg tagaaaactg ttctgcactc gcaacatatt gcatgaatat
     8881 ctttggatcg atttttgtat cgatcgtctg gatcgaaaag tcacctttcg ttaatgtgcc
     8941 ggttttatcg aataccactg tctcagtttg tgcaagcaac tccaagtaat ttgaaccttt
     9001 tactaataca ccgattttac ttgctcctcc gataccgcca aagaaactaa ggggtacgga
     9061 gatcactaat gcacatggac atgagatcac taaaaatgtc aatgctcgat agatccattc
     9121 agaaaacgcc gctccagaaa caacaagtgg aggtaaaaca gctaataaaa cggccaatcc
     9181 tacaacgact ggtgtgtaat agcgcgcgaa tttagtaatg aaattttcag ctggtgcttt
     9241 tttactgctg gcattttcta ctaattctaa taatttgctg atagtagaat tttcataaga
     9301 tttttctact tgaactaaaa atggtttatt tttattgata aatccactta atactgtttc
     9361 accaacatat acagatttag ggactgattc tcctgtaagt gctgacgtat cgactaatga
     9421 ttctccttcg atgatcgttc catctaacgg tacacgttca ccaggcttca caagtacaaa
     9481 ctgaccgatc tgcacgtctt cagggttcac ggtcatcaat ccttccgtcg tctgcacgtg
     9541 agctgtttct ggacggatcg ccatcaattc gcgaatcgat tttcttgaat gactgactgc
     9601 caatccttgg aaatactcgc cgatttgata aaatagcatc actgctacgg cttctggata
     9661 ttcaccgatc aacatagcgc caatcgtagc aacagacata agaaaattct catcaaagat
     9721 ttttcctttg acgatattca tcactgcctt cttcactaca tcatatccta tcagcagata
     9781 aatcaataaa taccctatca agcgaattgg ttcattaaaa tcaaataata gcaataaagc
     9841 gatacctgca agggaaaata aaatccggaa cagcgtattt ctctcttttt catttccatg
     9901 ttcagatact ttttccttat ctatttctgt tactttgaca tctggttcta attccttcac
     9961 tacttttttt atttcttgtt caatcgtagc caaatgatct tcctctgcgt caatcgttag
    10021 ttttccagaa gtgaagttta ccgttgcttc cttgactcca ttgatcttct gaactccttt
    10081 ttcgattttc attgcacagt tcgcacaatc taaaccttct aatctgtaac ttttcatttt
    10141 aatgacctcc tcgcctcaac atatgaatat ctcttcataa ctaattataa atgaacggtt
    10201 attcatatgt caaggtatcc gaaagaaaaa atgaaaaaca tctgcatcgg aaaatttctt
    10261 ccatacagat gttttggctt attctttctt tttcttttcg atcattgcca ctgctcttat
    10321 ccaacccgca cttgccttct tgatcttgac aggatagcaa ctaagtttga agcctgttgc
    10381 tggcaatttg tctaaattca ttaatttttc gataggacaa tatctttttt caatccctgc
    10441 aaaatgtcct tcccagatat tcgaagctcc actacgcttt caaaaatata gaaagagttc
    10501 tttaatgaaa attatttcaa ctttccataa acagtaaccc catataaata aaagacgtaa
    10561 aagtcacatg gaagaactta tacaggagaa cgcatagagt caggtgaaat acatgtatcc
    10621 cacctgactc tatgctttat ctaaccttta ttattctctt ttatacaatt tctgcaccga
    10681 atggcatcaa cgccaatcga gcaagtttga aagattgctt ggcaaaaggt atccctatga
    10741 tcgtgataca tagaaggatg ccgctgacga catgtgcgag agcaattggt aggcctgaaa
    10801 cgatcagcca gatgatatta acaatcaatg acatgccaga ctggtgataa attacttctt
    10861 tgccaaaagg cgcaaaagaa agggaggcga tcttaaaaca ttgcataccg attgggatac
    10921 ctatgatcgt gatacaccaa agtatccccg ctgctaacca gctaagacca ccgattagtc
    10981 cgccgaatat aaaccagatg acatttccta aacaactcat tgtatttctc cttctattac
    11041 tgtttttgat taaaactggg caaaaaatga ttttattctt ctttttttag cttccagtat
    11101 caaatattct gcaaattttt tttggatttc ttccgtattt tcttttgtta ctaatgtgtg
    11161 ttggattagt tttcctgatg gtcgctgatc caatcgttct tctgactgtt gcacgtccgc
    11221 ttgcgcaaat ccgataatcc gtttttcttt tgttacagca acgagcaata gtttattctt
    11281 atcatttagg tcagctgccg tttttgcttt tacgaatgat tctggatgat cagtaatcag
    11341 ctgattgatt tgaggtagat cttcttttac tgcccaccgt atttccatca tttctcactt
    11401 ttctttcgct catttttatc tccactaaaa aaatcgactg cggcaattgc atctatccag
    11461 ctttgtgcaa tgatctcatg tccgccaatc gttgggtgga ccccatcttc tcttgtatat
    11521 ttcgaaaaac cataaacaat ccctaaagca ttgaatatac catctaaagg aaccagcaat
    11581 gcgccatatt ccttagcaag tttacgaaca atttggattt tagggtctaa gtctttacgc
    11641 cagccatgac ggtcgtcggt tataggaagt acaaacggct ccatcaagat gatgttgcag
    11701 attcccactg tttgaagttc atttagtaat tttcgataaa cggattcaaa ttgctgagca
    11761 gatttctcag ttccgaatat agcctgatcg ctagtattat gccaggtatc attgattccg
    11821 atcaaaatcg atacatagtc aggttgtaaa gctaaacaat cttcttgcca gcgtacttgc
    11881 agatctgcaa ttttgtctcc tcctatccca cggttcatgc attcaaattc catcgttgga
    11941 tattgggaga ttagttttcc ggcaatcaaa agtggataac ctttacctag atcagttgct
    12001 tctgctcggt ctcttcctgc gtctgtaatg ctatcaccga taaataatat acgttttttc
    12061 atttgtcaaa aactcctttt tgaataaaac gatgattttc ttccttatat tatcccataa
    12121 gccctatcaa gacgaaagag aaaatatatg tataaaaaat gacaccagcc tagtcccttc
    12181 aaacaattga atgaacgctc atcaagtgtc tagtttttta tgctattttt ttcttaacgt
    12241 gccggattcc ccttgattcc ttcgttgttt ggtccagaga gatcgatcac acctaagctt
    12301 ccgtcaatca gaccactgat gacgccatca gaacatatat ttataggctc atctaagact
    12361 tctagtaaat gtccctttac taatatctct tctagattgc ttgggataga ttggtcataa
    12421 ctttatctgg tccgatgatt tcaagggtga attgaactta catatggatt attgcatgct
    12481 gaaaatacgg acctactcca tcttcgaatg ttactattag tttgttttca ggtgctagat
    12541 gctgctttat ttcaacagca gaagcatcat caaatcagat ttccatttga attaccttct
    12601 ttgtaaatgt ttgattgatt gcgatttcgt tatagaacct tgtgaatcaa atagcaattt
    12661 cttttgcttt cttctcttgt ctgctggaaa cttcctttat cccgtatttt aaaaaaagaa
    12721 ctgcgagagt tcgcagttct tttttagaat aaacggtgct ctccggccaa ctcctcggtc
    12781 acaagtcaca atagtcatca aacatgaaaa actgtttttt gaaattactc cttgtgactc
    12841 ggagctgaac ggcaggcgca caacctcttc cttaaacggt gttcaaaagc cagtttctcg
    12901 gtattaagcc aaatttatgc aaaaatgtgg aaagccattt ccacaaaatt tttcttaata
    12961 ctcgaaacta aacagctttt tcacaacctc tccactaaac ggtattcaaa agcttacatc
    13021 tgcggtaata agtcccgcca attcaaaaac atgaacagct gtttttgctt ggctgttcta
    13081 attacttgat gcagaacagc tttttcatca cctcttatgg ataaattcgg ttcaacaaac
    13141 gtgggaatgg aatagcttca cgtacatggt cgataccagc aatccaagtg actgttcgtt
    13201 caagacctag accaaaacca gagtgcggaa cagaaccgta tttacgtaga tcaagatacc
    13261 atgaatattc tttttcatcc aaaccgtgat tacggatttg ttctagcaag aaatcatagt
    13321 ctgttgcccg ttcgcttccg ccaataattt caccgtaacc ttctggtgcg atcatatctg
    13381 cacagatcac cacgtcttct cttgttggat gtggtttcat gtagaatggc ttgatggctt
    13441 ttggatagtt taggataaag acaggctgtt cgaatgaatt cgcaatgaac gtttcatgag
    13501 gtgaaccaaa gtcttcgccc cattcgatgt catcaaatcc atttttcttc agtaattcga
    13561 tcgcatcatc ataagtaata cgagggaatg gcaattttgt ataagttttt aagacttctt
    13621 tgtctcgtcc tagtacatct aatgcatatt cgcaatgatc taaaacattt tgtactaaga
    13681 atgctacata ttgttcctgt acttctaaac tttcttcttg atgagtgaaa gccatttctg
    13741 gttcgatcat ccagaattcg atcaaatgac gtcgtgtttt tgatttttca gcacggaaag
    13801 tcggaccgaa tgaaaagact tttccgaaag ccatagcagc agcttccatg tataattggc
    13861 cactttgaga taaataagct ttttgatcaa agtaatttgt ttcgaataga tccgtagtgc
    13921 cttctggtgc agaaccagtc aagatcggcg gatcaatttt gacaaaatga tgttgattaa
    13981 agaattcata cgttgcacga atgatttcat ttctgatctg cataatcgca tgttgtcttg
    14041 aagaacgcag ccataaatga cgatgatcca tcaagaagtc tgttccgtgt tcttttggtg
    14101 tgatcggata atcgtggctc tcgcttacca cttccacatt tgtaattccg atttcataac
    14161 caaattttga acgactgtct tcacggattt ctccagttac taacacggat gtttcttggt
    14221 gtagattttt agctgtttgg aaaacttctt ccgacacttc gctttttaca actacacctt
    14281 ggaaaaaggc tgttccgtct cttaattgta aaaatgcgat ttttccgctt gatcgcttat
    14341 ttgcgaccca agcgccgatt gttactgttt ctcccacatg gtttttcgaa tcgatgattt
    14401 gaatttgttc cacgtatgac tctcctttta tattccttga atttctttag gattaatttt
    14461 gacttttact ctcaataaat tgcttgattc tgcgtaccgc ttcttctaac gtagcgcgat
    14521 cagtagcata actcatgcgg acattttctg gtgccccaaa gccttcgcca gtcacaagcg
    14581 ctacccctgt ttcttctaaa agatcttcta cccattgtgt gacattttca tatttacaca
    14641 tgcgtagcgt ttcttttaca ttaggaaaaa gataaaaagc tccttgtggc ttttcaagag
    14701 aaacacccgg cagttctgcc acaagcgaat ataacgtatt caggcgttct tcaaaggcgt
    14761 tccgcatttc ttccactgta tcttgctcgc ctttcaatgc ttcaacagct gcatattgac
    14821 tgactgctgt cggattactg gttgactggg aagcaacagc gatcattcca ttgatgatca
    14881 caggatttcc caccgcataa ccaatgcgcc agcctgtcat cgcatatgtt ttagacacgc
    14941 cgttgatgat gatagtctga tttttgattg cttctgaaat cgttgcaatt ggagtaaact
    15001 cattgccatt ataaactaaa cgaccataaa tatcatcagc aactatcaaa atatcatttt
    15061 ttactgccca ttcaccgatt gcctgcagtt cattcttgct ataaatcatt ccagtcggat
    15121 tcgatggaga attgatgatt acggcttttg ttttttctga acgtgcttgt tctagctgtt
    15181 caacagtaac tttccagcta ttggattctt cccctttcac aaagacagga agtccttctg
    15241 ccagttttac ttgctcaccg taactgaccc agtaaggcac aggaatgatg acttcatctt
    15301 gcgggtcaag gatcgtttgg aaaagggtat acaaagcaaa tttcgctccg tctgttacga
    15361 ctgtttgtga aggttcatag acaagtccat agtttttctt cagataatca acgattgcct
    15421 gtcgaagctc tgggattcct gctgttggtg tataatagct agctttccca ttgcggattg
    15481 cttcgattgc tgcttcttgg atgttttctg gtgtcgcaaa atccggttct cccacagtca
    15541 aactcagcac atctctgcct tttgctttta atgccttggc ctttgccgca gctgccaaag
    15601 tgacagacgg ttctaatcgt tttgttcttt ttgataactc catcccattc attcctttac
    15661 cttttaaatt cccttgattg tcttgacttc atctccagat tcaaagccaa tcaggtaata
    15721 attcagtttc ccatttgttt cttttcctac tacttcccac acaggctgat catcatacat
    15781 ccctaaagca gctttttcga tttggatttc aggatgggcc gcagcaattg tctgttttgc
    15841 ttcgttttca gtcagtccct ttgtttgatc caatactttt actttttcac cagatttagg
    15901 aatgataacg gcgatttctt ttcctttatc atttgtacct gtcagtgaaa agtatgtctt
    15961 ctttcgagta aaccaataaa aatgatcggt ttcctcaaga tttgcatatt tctttgcgat
    16021 ttctactgct tctttcttcg cctgcaccgc cggacgactg gaacgcaagt aaaaaatcga
    16081 gctgatcacg atgaccgcta ataaaaatac gatcaagcca agtaacacgc gattaatcgt
    16141 tttttccttt gtctgttttt tcttcaaggg tcgtcgctcc tttatcttca ttccttttca
    16201 ttatagcaga ttttaattat gaaaaaagac agctcctcta acttccttct tcatttttct
    16261 ttaagaattc atggatatcc tgatagattt cctccatagc tagctctttg atcggtactt
    16321 ttttcggtaa tgcatggatg atccgtgcgc catattttgc agtgactagt cttcgatcca
    16381 aaataagcaa tacgccacga tctgtctccg tccttatcaa gcgacctaat gcttggcgta
    16441 acttcaaagc tgctttaggt acggattcct ggtaaaaagg attgatcccc tctgattcta
    16501 aataagcgtt cctagctttg accatcgggc gaagcggatt atcgaagggt aaacgtgtga
    16561 ctacaacgat ctgcaaagca tctccaggca aatctacacc ttcccaaaag ctgtcagcgc
    16621 caaacaatac gcttttttct gacaaaatga agcgtttcaa aagcttctcc cggcttccac
    16681 caaacccttg agctagtatt tctcgtcctt tttctagcat agacagatgc attttctgat
    16741 agaccttctg caaaacatca tgagaagtga ataacacaag tattggccga tcttcttgtt
    16801 cgatcagacc tgtaagtgct gtctctaaat aatcgatata tgcttgattg ctgacttgat
    16861 ggacggcagg tgcctctttt ggcacataga tccttgcctg tttctcataa tcataaggag
    16921 aggcaatcac tttaagaggt gctgcttcaa tgccaagcct cttagagaga tagtgtcgat
    16981 tagggccgat cttcagcgtt cctccaatat aaagaatacg atcatatcga ggataccaaa
    17041 cagtcgacgg caacatagcc gcttgaaaat catggagatg aaaaatcatc tgctgcgctg
    17101 tgttcccagg aacgaaccaa tggatcaaat gatctcgcca gtcttccagc cattgatcca
    17161 tcagcaagta ttgcttgtct aattgatcaa ataggctata taaacttgct aaatcgatcc
    17221 gcatctggtt tgtccagctt tcttggataa tctcaaaagt cagacgcatt tgtgactgta
    17281 gctgctggat ctcctgataa aaaagctgca ggtgatcaat ggctgtccca gattccagtg
    17341 gcagctgatc caacatctct tttgtcatca tgacttcttc tggatactgt ccgttaggtt
    17401 gcttgccgct cactaaactc attaatcctt ctgccataca aatctgtgct tcgcatagcg
    17461 cagaaagttc ttctcgataa atcgataacc agcgtaaggc ttcatgttct ttcggtaaat
    17521 agctttgtat tcggtcaaac agctgatttg gttcttctaa ttgctggatt tgtttatgga
    17581 aatagttaat acttaatcgt ttgtcattta ctttttcagc gatttccggc aaatgatgta
    17641 cttcatcgat caacaaaaat ggactagctg gaagcaatgg ttcttttcgc tgtgtttctt
    17701 gtactaaaaa cgcatgattg acaatcaaaa aattactttg cctgattttc ttttgcaaga
    17761 aacgaacaaa gtcttgttcg taaaatgact gatttcttgc taaaaatcca atacctctgt
    17821 gcgcgatatc tgcaaagaat gaatggttca aatttgttaa atgtaattca tccaaatcac
    17881 cagtcttcgt ttgcgtcagc caaactaaga ccgccatttg atacaaagca tattgttttt
    17941 gttctggcgg ttccacaagt gtgcctttaa aacgctgcaa atcaatatag tggcgatagc
    18001 ttttgataat tacaggttgt atgggctgat ctagcaattg attcagcaat ggaatgtctt
    18061 tttctatgat ctgctgctgc aaaactagcg aaacggtact gatgacagcg ggtttttcag
    18121 gtgtagccaa ataactcaat ggcagcagat aaccgattgt tttacccatt cctgtagctg
    18181 cttcgatcat caaatctttt gattcatctt ttgtgaaatg gtcgtagacc gcattcatca
    18241 gtctgttctg ttcttttcga tacatcagtg ttttaccaaa cattttttct tttgcttgtt
    18301 tttttcttgg atatgtccgc tcgccataat ggacggatgt gaatagttcc acttcttttt
    18361 tctgcaaagc tagcccatcg acgatttcta atgagggatc aagtggctct ggtttttctt
    18421 tcatttcttc aatcacatga taaatgaaac gactcgtatc catacctgtg tgtctactta
    18481 atcgcgcaat ctgctctaac gtgatgattg gcaattttct catccgttct tcgatcagca
    18541 aaagaagttg acctgtcact tcggcatcac tatctgcctg atgaggattc tcatgaataa
    18601 atccaaggct ttctgacaaa tcagctaagc gaaagcttgg ttccgtcggc aagaaaattt
    18661 gtgcaagttc tactgtatcg atgcctggta tcttcaaact aggaagtccg catcgcatga
    18721 gttcatggtt caaaaaatta taatcaaaat aaatattatg cgcgacaaat atggtgtctg
    18781 ccaaaagatt gtaaatcgtt tgggcgacat cttcgaaata aggcgctttt tggacgcgtt
    18841 gattcgtgat ccctgttaaa tgctggattt gttttgaaat cttccgccct ggatgaatat
    18901 cgatcgaaaa acgtgaagtg atccgacctg attcaatcat gacgcagcca aattggatga
    18961 tccgatcttc ttttggattc gtcccagtcg tttcgatatc aacgactgca taagttcttg
    19021 gtttcaaaat atcttcctct tctcctgcct ctaatgttct tttgaaatta tactacaaag
    19081 tgcagaaaaa tactctcatc gctttttaaa gaaaatagac aaaaacgccc agacacgcaa
    19141 atgtctgggc gtttattttt ggctctataa tttctaggac tgatagaaaa tcattctatc
    19201 ggtccctttt gagcatgaaa aaacaaaaca tacagaagct ccgttagaat tgaatcacca
    19261 caacacaatc aaaggagcgt tctgtatgcc tgatcttcat catatcaaac tactacttgg
    19321 aatcaaagat aaaaacattt tcatcacaaa tgtggaatcg aagagcatta agaatatcaa
    19381 gagtcttgtt gtttctgcga cgttaagtaa agaaattcgt cgctgtcctt tgtgtaaaca
    19441 gatgaatcat gaaggcatga tcgttaagaa cggaaagaaa aaatcgctca ttcaacttaa
    19501 taaatgtgcg aaccaactga cttatcttgc tttagcgaaa caacgctacc actgtcgtgg
    19561 ctgccacacc tattttacgg cgaataccta cattgtcgat agaaactgct ttatcgctaa
    19621 acaagtgcgc tataaaattt tagaagagct aactgaaaaa caagcaatga cgacaattgc
    19681 taagcattgc ggcgtttctt ggtcgaccgt ttctcggaca ctcgcttctc tgatccccat
    19741 gacaaaagta aaaagaaatt ggttaccgcg ttgtttatta atggatgaat ttcgttcact
    19801 gaaaaatcaa gtcggtccct actccttttc ttgtatggat ggcgatactg gaaaattact
    19861 ggatattctt ccttcacgga agaaaaaggc tctcgtttct tattttatgc aatttgaacg
    19921 acgcgcacga ttgaaggtaa aggtcatcgt gacggacatg aatgtttctt atgcctctct
    19981 gataaaggaa tgttttccaa aggcaaaact cgttgtggat cgttttcaca ttgtcaaaca
    20041 tctcattcgt aaatttgagg atattcgcgt acgaatcatg aaaagctttg atcgaaacga
    20101 tccaacacaa gccaaatatt atcgacaatt aaaggcgttg tctcggcttc tgatcaaacg
    20161 acaggacaag cttgtttatg acaaatggac caaatggcgc aattttggtt gggcgtatct
    20221 caccgaaagt gaagtggtgg atcgtctgct ttcgatctct gacgaattac gaatcgccta
    20281 tttttactat caagaaattc ttcaagcgtt tcacgacaaa gaggcggaca ctttctttaa
    20341 acttgtaaga acgatgccca attccgttcc aaaagaactg cattctataa aaaaagcttt
    20401 tataaactat gaatccggca ttcgtttagc cctcgaattg ccttattcaa atgccaaaat
    20461 agaaaatctg catacccaca tcaaagcatt gaaacgagtc gcttatggct ttcgaagctt
    20521 tcggaaaatg aagaccagaa ttttcttact aaataatctg attacctatg aatcaaaaaa
    20581 catctaaagt agaaaaggaa ttctacctta gatgttctta tctcactcta tcagtcctat
    20641 ttgacaaaga gccttatttt ttagtatagg ttaattaagc tttagtaacg tttgttgctt
    20701 gaggtccgcg ttggccttct tcaacatcga aagttactgc ttggccttct tctaaagttt
    20761 tgaatccgtc gccttggata gctgagaaat gaacgaatac atcgtttccg ttttctgcag
    20821 tgatgaatcc aaatcctttt tctgagttaa accattttac tgtacctgtt tccataataa
    20881 aaatcctcct tgtgtatcaa cacatatttt gcaattactt gaatggtgta tatctggaag
    20941 atgtttattt gaaacaagct accacagatt accgaacaaa aactactcct atagtatatc
    21001 ataccgttta caaaaaagct agagtttttc gacttttttt attaaaaaaa gttttctcag
    21061 cgattacata aagtgaaaaa ccgaactttt ttttaaaata aacgacatat tgttcagttg
    21121 gtgttttttt gctctgatgt tcttttttaa actaaaaaaa ttattctttc tgactactta
    21181 tcggttctgt ttcaacggtc gaggctgggg aagattcttt agtaggtctg atgttctcat
    21241 ggtatttctg atagcctatg acagttacca gaagaacaag gcaaaccaat acgaccaacg
    21301 agattagttt ttcttttttg ctcatatcta tacctcataa ataacaggat gatgtccatc
    21361 atatttctga gtatgagtaa aagcaaaagc tgcagctgta gaatgtaaga aatgccagca
    21421 actttcataa tcacaggtcg gacagtacca aaagtaacca aatcttggct gcaaagaccg
    21481 ttcttctgtt tcaggaatcg cagaatcaag atctggtgtc tgtacataaa catttttgta
    21541 cagacgtgtg cctgtaatag gaaaccgctg tgtttcttca gcaaaaactg gctgacttgt
    21601 taaacttagg gatagagaca gcaaacacca taacagtctt tttttcataa agacctcctt
    21661 atcgataagt ttttcccaat taaaatcata tctcaagaac gcccgttatt cacattttgt
    21721 tcataaatga tgttttttgt atcataatcg tcaaaaagag gtcgtgacca cgtcacaacc
    21781 tcttttttaa acggtgttcc agaagtagct tcttcggaaa taagccgaaa tttcacaaaa
    21841 atttgagaaa taatttttgt caatctcttc ttatttcttg aagctgacca cttctgtcac
    21901 aacctcttcc ttaaacggtg ttcaaaagct tgcatctgcg gtaataagcc caccaaacaa
    21961 aaaatatgaa gagctatttt tgcttgctgt tcttattact tgatgcagaa cagctttttc
    22021 acaacctctc atacacggtg tttaatcagc tgaccttcgg tattagctca aaaaacggca
    22081 aaatatgtga aactattttt ccgtttgttt ctctaatact caggtcaaaa cactgatttc
    22141 acaacctctt ttaataacga agaatcgctg tcagactctt ttcatctggc gcatcttttt
    22201 gatccaaaat aaacactttt ccgccattaa tgatcacatc atctgctaat gcattcaaca
    22261 cttgacgccg atcatattct gtttcaggat cttcaccgaa accatcagct aagtttgacg
    22321 tagcgataaa taaatgtgac acttttcctt ctttcgcagc tggaacgata tcaactaact
    22381 gatcgatgaa tttcttatct aagagtttat tgtattcttt tgattcttga gctgcgagtt
    22441 cacttgacag cttcttcgcc ccttcttcga tatctctaaa ggatagctgc gcaggagaag
    22501 cagaaatcgc aacgtctgca caataatagg gatttttagc aatttttttg aacatcgtct
    22561 gattttctgg tagagcaaat aaataaatcg gccattgttc tggattttcg aaagaatcct
    22621 tcaagtacgt atcaactgct tggtaatagt tgacccaatc gatctctact tcttcatctt
    22681 ttggatttac gccatggaaa gttactccat ctcgggctcc gcctcctcca ttagaagaga
    22741 agttcaaacc gccacctgtc agttcagatc ccaatgcagt aacgacatca accggtgccc
    22801 cttctggtag agatacttct tttacttgtt tgttgctgac ttcatacaat ttcatggagt
    22861 cgcggttcaa tcccaataaa taataagaat agttgaactg cccatttttg ataatagcca
    22921 gtaaataagg aagatcactt acatagtatt gatcgtctac cgggatactc aaacgatgga
    22981 tataggtttg gtcagcagtt ataatgaccg ctacactcgt agttgcacta cgccaaaacg
    23041 aaggatctcc taacaaattt tcaatttttt cttggaacgg ggaccagtca tgttcggaat
    23101 attttttctc aaaacgtttc tttgcttctt tcgcaaaatt tttgaatttg atctgatctt
    23161 tttccacatc ttgatgggcg acatgcgtat tcagcatgat cgtgacgaat ggtcctttag
    23221 cgccttctga agtcaattgt gacaataatt ctttatcctt ttttgccata aacgtacccc
    23281 tcctaaaaaa atcattcctt tgtttctatc taaagtctac cacaacacta tttttccata
    23341 caataaaacg tatctaaaaa aataaaacgg tttctacggt tttaaattta gctatttttt
    23401 taagttatct tcataatttc ctcaattatt tagccccagt cttcaactat tcttcatgaa
    23461 atgctgataa actaagaaaa agaataaaag aggtggatct tatgcatttg attatgattt
    23521 tcagtttatt aagtattatc agtttatttg ctttcagcgc ttcccgctta ttagatgcgg
    23581 aaacacagcc tattcctgta aaagtacgta aaaacgaccg ctaaccttcc ataacgtgcg
    23641 ttcttatcct aaagtttttt cagaaacatt gaaactctct cccctctctg ataaaatttt
    23701 aatttgtagc gaaacaaatt aattacaagg agatcggata tgtccataaa aaaaacacgt
    23761 ctagtcctat tattggctag tctcattctt tgccttgctt cttttctacc agctgttgct
    23821 gtgcaagctg aagatacttt caaagtaaat gcaaaagcag cctttgctgt agatgcgcaa
    23881 agcggtaaga ttctttatga tcaagatgga gaaaaaacca tggggatcgc ttcaatcaca
    23941 aaaattatcg gtctttacat cgtccttgat caagtaaaag aagggaaact atcatgggat
    24001 gataaagttt caatttcaga ttatgcagaa aatttgagtg tcaccccaga tttatcaaat
    24061 gttcctttgc ataaagaaaa cacctacacc gttaaagaat tattcgactc tgcaatcatc
    24121 cagtcagcca acgcttcaat ggttgccttg gcagaaaaaa tctctggcag cgaagcaaaa
    24181 ttcactgaac gaatgaaaga acaattgaaa gattggggta tcaaagatgc aacgatcgtt
    24241 aatgcatcag gactgaataa ctcttatctt ggcgaaaacc gaccagaagg tactggagaa
    24301 aacgacgaaa atcaaatgtc tgctcaagat gtggctatcg ttgcccgtca tttgatcttg
    24361 gattttccag aaatactgga tgtatctagc actacgacac aaatgtttgg cgaaaacacg
    24421 caatcaccag tagaaatggt caactggaac tggatgctcc caggattcgt gaattataaa
    24481 gaaggcgtgg acggattaaa aactggtacg actgaacttg caggagcctg tttcgtcggt
    24541 acgatcacta aaaacgatca acgaatcatc actgtcgtat tgaatgcaga cggccatgcg
    24601 gaaaacccaa gtgcccgttt caatgaaaca gctcgcttaa tggattattg ctacgacaat
    24661 tggtcagaaa aagagcttgg aaaagccaat gcaagtatcc ctagtctaaa aaccattgat
    24721 gtaaaagacg gaaaagaatc aacagtgccc gttgtgctta aaagtcctgt aaaagtatgg
    24781 gtacggaacg atatggatac tggaaaatta acaatcacac caactcttga caaaaaacaa
    24841 gtcactgaca atgagatcca agcacctatg gataaaggaa caaaaatcgg taccgcaacg
    24901 atcaccttgg cagaagataa attaggttat ctagaagaca acaacgcgcc atccacagaa
    24961 atcatcacgg ataaaaccgt agaaaaagca aatattttcg ttattggctg gcgacgcgtc
    25021 gcagaatttt tcggtaactt gttttaattg aacaaaaaga aaaaagcatc tttccatgtg
    25081 gaagatgttt ttttgctttt tctagtttaa ataacagctt ttttcatcta ttttcgttat
    25141 actgtataag aaaaaggagt tgaatttatg aatctaacca gagatctgat ttttttggtt
    25201 ctctatctta ttggggtatt ctccatcgtt tattggcgaa aacagaaaaa ggatccttcc
    25261 ttgttctttt acagcagtac gtggacattt gcggtaatct tgacttattt tgtcgtgttg
    25321 gaaatttttt attcgacctt ttattttttg attcccttag tgtttttcag tatctttgcc
    25381 ttttcctatt tttcagaaaa gcgaaggctg ctgaatggtc ttttattcaa tgttttcctc
    25441 attagttttg gtatctactt gtttgtcttg ctatacgaaa cacaaaatat ttttcttggc
    25501 ggactgattg ccttgatcac gatcccgtta ctgcttgtct ttctattcgg catttatgga
    25561 ttgatcgttt ttcttttttg gaacggtgtc acagttttac gtagagagtc gcattcatta
    25621 gctaatcttt taacgttgat actagccatt tttcttacat tgtttcttgt ttttgacttt
    25681 ttcttgttaa aatatttacc acaatggata aatgctttgt ttttctgcat cccattgatc
    25741 ttgatctatc tatttatcgt attctacaac tttttgactg tctcattctt gtatcagttc
    25801 aaccgccctc gatacaacca agacttcatc gttgtgttag gcgccgggtt gatcaatgga
    25861 gaaacagttt ctcctcttct tgccaagcga atcaataagg cgattgcttt ttattgggca
    25921 caaagccgtg cgacattaaa tccgcctatc ctattaatgt cgggtggaca gggagcagac
    25981 gaaaaagtac cagaagcaat ggcgatgaaa caatatgcca tggaacaagg aattcctgaa
    26041 agagatattc ttgtcgaaac caattcgaca accactttgg agaatatgcg ctattcaaag
    26101 gaaatcatgg atcagcaaat gaaagggccc tatcgcgcga tcttcagttc caacaattac
    26161 cacattttca gagctggtct ctatgcacga caagcgaaac tgaaggcaaa tggcattggg
    26221 gcaaaaacag ctttctatta cttgcctaac gcgtttttaa gagaatacat cgccatcttg
    26281 atgatgaaca aaaaaagaca tatgatcatt tgcggattgc ttttcgcagg ttccgcattc
    26341 ttatcactga tcactttact tttctaaaaa accaaggtgt gacaaaacat atgtcacacc
    26401 ttgttttttt cttttattct cttgacgatt ggcaagaata gtattccttt tttgacggct
    26461 acttgctgtg cagaataaat accgctgttt cctgaacaca taaagctgat caagcagatc
    26521 ataaagaagt aaacagcagc ttgtgaacca aataattcga ttcccatcac aaaacaggca
    26581 atcggtgtat ttgtcgcacc agaaaatacc ccgataaaac ctaatccagc aagaaaagga
    26641 acagaaacat ggagcaaagg cgctagtact gcgccaagcg ttgcaccaat ctcaaatagt
    26701 ggtgtcactt ctcccccttg gtaccccgca cctaaagaca agaccgtgaa gaataatttc
    26761 ccaataaaat cataagcatg tgcctgtcca ttaaatgatt cctgcagtat cggaagactc
    26821 aacccaaggt aacgttgtgt ttgcaaaatc aacgctgcgg ctacaactac tgctccacct
    26881 atcgtatttc gccaaacagg atgaggaatc cattgcgcat accgcgcttt taaaaagacg
    26941 atcgaacggc tgaataccca accaatcaaa ccaaaagcaa tcccagcaac aaaaactttg
    27001 aagaacagca acatactcca ttcaggaatc acacccattt ggtaatgtag atgagaaaca
    27061 ccatagcttt ctgtcatgaa atttgcaaaa agcgcagcaa agaagctagg aaagattgct
    27121 tctgttcgga ctttaccgat tgccaacact tctaatccaa ataatgttcc agctaaaggt
    27181 gtgccaaata cagaactaaa acccgcactg attccactga taaccaaaat ctcccgttct
    27241 gctttatcca atcggaataa atgcgctata ttatcagcta atgctccccc catttgaact
    27301 gctgttcctt cacgaccaac agatccccca aataaatggg tagtgatggt cccaaacaag
    27361 gtcaatggaa tgagccgcaa agggatcttc tcttctcctc cattcccttg atcgatcact
    27421 aagttattcc cacgactaga aagaccgcca tgatacgcat aaagataagc aaaaagcgcg
    27481 ccgctgactg gcaatagata aaatagccaa ggatgtgcta gtcggatatc tgtcacgaac
    27541 gtcaggctat ttaagaaaaa agcagacaag ctccccatga atactccgag aatcgctgtg
    27601 accaccagcc acttcaacat gtacatcaaa atacgcactg gactcggtaa ttgtttttcc
    27661 ataaaaaatt cctcctcaaa taaaaaaacg cctactaaag aaaggggctg gccccagact
    27721 ttagtaggcg tcattagcta tcttacgtta gcatttaaag gcgaacacca tcacctattc
    27781 acttccatta aaagatagca tatttttctg taaaaaacaa taaaattatc gttctttctt
    27841 tacacgttca gcaaattcat agaaaggagc caatttcgtt aactgttgat tacattgatc
    27901 actatcatga caaatataat tccccttttt cgtatacgtg ccatcagaac cggctttcgt
    27961 tgtagaaaga aagagcgaga cattcgatgt tttctgacag atcgcacaga ttcccttatt
    28021 aatcgttggt gataaagtac cgctgatccc ttttaatttt ccatcttcgt aataaaccat
    28081 gaattttttt tgcgtccctg gatcattcca accgatgtac gtatgtgctt gcaagtcgat
    28141 ttcattccaa gcgggttgtt tgagtttttt cacttttcgg aataatttct cgatttgtgg
    28201 tttgctcggc tgcataaacg gctggacgat ttgcttcagc tcctccaatg ctcgttctgc
    28261 ttgcgttttt gtcagtttta catctaaaac tgtcgttaaa aacgtatcga tttctgatgg
    28321 ttcgtaacct aatacatcgc gaatcttttc agctgctaga gcctgaaccg tttgtaccgt
    28381 ttttgagtca ttgacagatg agtacgcatt taataactgc tctacttctc tttttataaa
    28441 aaaatattga tatggtttca ttgtttgttc catgatttta aagtcctttc ttctaaccaa
    28501 agtgcatact ttgtagaaaa aagtgatctt ctgcaaagta tgtgttacct gaagatcccg
    28561 gactctttta aataagatac gttttgcatc ttatcatcac cccctttaat gttcattctt
    28621 ctatgtacat gattcattcg ataaataaaa gtaaaccgta tcttgagcag atagtcaact
    28681 gcaaacagaa aaaggactgt gacaaaagtc gtgtcaaagt ccctttctac aaacaaacgg
    28741 tgttccagaa gtagcttctt caaaaaataa gccggaattt cacaaaaatt tgagaagcaa
    28801 ttttcgtaaa ttccttctta tttcttgaag ctgacccact tctgtcacaa cctcaatatg
    28861 gtctattatt ggttttacct gttaaatcga ggattctttt ccgaagtaac gttgccatct
    28921 cttacgcata cttgctgaca taggctgagc ggcttctttg actgcgcagt atttgtctac
    28981 gaatgttacg atatatcctt ctttgtactt aggcggtgca atcgttgcgc cccacatgtg
    29041 cttcaaaatg atatctcgct caagatccga caaatcggtg atcttttctg cattctttac
    29101 agcgattctt ggatggatat acgcatgtgt gccttcatca aatttcgtcg tacgccaatc
    29161 atagtagaac agatcatgca aaagtccagc acgcgctgtt gctttagcat tgccacccca
    29221 tttttttgcg agcagataac tatagtaaga aacactgatg gaatgctcca aacgagtgga
    29281 atgaacatgc tgtgtgtaat tcgctaattt tttcactgct tctgtttcta aaagatcttc
    29341 tacataagac atatattctt cgtcttcacg ccatttttct gtcataatta tcgatctgcc
    29401 acctttttga atttcatttt cttctgaaat tgatctaagt ataccaccag tgttcggatt
    29461 attctagtcg ccttggataa aatagccaaa gcttaatagt tccttaatca taaagaaaaa
    29521 tgataaagaa caatccctgc cgcaacccca acattcaacg attccgcatt tcctttcatc
    29581 gggatatata cgttctgatc agtcaaagac aagatttcct gacttacccc ctgaccttcg
    29641 ttccccatga ttattgcgaa gttatctgat ttttctactt tgtctaatgc gtgtgcttct
    29701 tcatttaatt ctgtgccata cactgtaaac cctttgtctt tcattaaagg aatcacttct
    29761 gtcaaatctt tttgcaacac aggcaaatga taattgcttc cctgcatgct gcgcagcacc
    29821 tttgtactat aaatatctgc cgttcctttg cctaataaaa caccagccat atcaaatgca
    29881 tctgccgtac ggatcatcgt ccctacattt ccaggatctt gtacattatc taataacagc
    29941 catcctcctg aaaaatctgg cgtgccttca gccgttaacg ccatcactgc taagattcct
    30001 tgtggtgtag gtagatccga tacagcatcc atgacctcat ccgaaactag aaaagtagaa
    30061 atctctttgt ttgcggccag ccagtctccc cattctttca tgcctcgctg tgtcacaaaa
    30121 agttctttta tttctgcatc agacgacgca gcttcttcga tcagatggaa cccttccaaa
    30181 agatattctt ccttttcttc ccgatatttc tttttatgta gtttttttaa ttctttgatt
    30241 cttggatttt ttgctgattg gatctctttc acattcctca cctccccatg attatatcat
    30301 ggaataggtg cttgagcttg tttcatccta aaaaaatcgg tatcattaat ttataaaata
    30361 ggaaagaaag gtgacgaaca tgcgcaaagt taaaatgaac gtccaaggac gcgtccaagg
    30421 cgtaggattt cgctacatga ccaagatggt cgctgatcaa ctaggcgtga ctggaacggt
    30481 aaaaaacgaa gacgacggct cagtcacaat cgaagcaatc ggcaatgacg acatcatcca
    30541 gaaatttatt gaagaagtca agaaatcacc gagcccaagt ggacgagtgc agtatgtgga
    30601 tgtccaagaa gacccgatga ttgaggaacg aaagaaattt gatgtggtgg gataaggttg
    30661 tgaaaaagct ggtctgcatc aagcattaag gacaggttgt gaaaaatagc tctccatatt
    30721 tttcaacagg ctggacttaa tgccgtagat gcaagctttt gaacaccgtc aataaggttg
    30781 tgagaaagtc gcttagtttt gagtagtaag gagaattttg tgaaaatggc tttctacatt
    30841 ttttcataaa atttgactta ataccgagaa actgactttt gaacaccgtc gataaggttg
    30901 tttttgaggc gctttgcctc gagtattaag gagaaacatt ttcaaaatag cttctcatat
    30961 tttgttaata ccgagaaact gacttttgaa caccgtcgat aaggttattc ttgaggcgct
    31021 ttgcctcaaa aattaaggac agcagtgaaa aagctgatct atcacttgca gtgagttcat
    31081 ttgactccgc tttttcgggc agaaaaaaag tttttagttt attaaagtaa gaaagaaaca
    31141 cttggaatca ttctactttt tcctagtatt tctttcttga ttttttgtct ttttttcaaa
    31201 atttttcgct acgtaaaaga acgaatattt atatgaaatt tctatgaagt tgattgaatt
    31261 ccatgcgctt ttttagtata gttaagtttg tgtaaaaatt atagaagagg aagtattcta
    31321 tgaataaatg gaaaaactgg ttattgggat ccggacttgt cagtatcctg ctctttttat
    31381 ctggctgtgt gcggatggat tcaaacggaa accctgacac ttcgggaatc gtttatcgag
    31441 tactcgtcca tcctatgggc caagcgatta catatctagt tgaaaatttc aattggtctt
    31501 atggctgggc agttattgca atgactgtga tcgtccgtat catcatcttg ccactaggta
    31561 ttagtcaatc gaaaaaaaca atgatccaat ctgaaaaaat gcaagcgtta aaaccacaag
    31621 ttgaagcagc ccaacaaaaa ttgaaagctg caacaacacg tgaagaacaa atggcagcac
    31681 aagcagaaat gcagcaagta taccgcgaaa acggattgag tatgaccggc ggaatcggct
    31741 gtctgcctct attgatccaa atgccgatct tctctgcctt gtactttacg gcacgttata
    31801 cagaaggtat tcgggaatca tctttctacg gcatcgattt aggctcacca agtatggtac
    31861 ttgttgtcat tgcaggggtc gcttatctgc ttcaaggata catctcaacg atcggtattc
    31921 ctgaagaaca gaaaaagacg atgcgtacga tgctgatcgt ctctcctgct atgatcgtct
    31981 tcatgtcgat cagtgcgcca gccggtgtta cactttactg ggtagtcggt ggtgtgttca
    32041 gctgtctgca aacattcatc acaaacgtta tgatgaaacc acgtttgaaa gcacaagtgg
    32101 cagaagagtt gaaacaaaac ccaccaaaac aagtcgtcac tccaagaaaa gatgtgacag
    32161 aatcagctaa accagctgac agcaaacaag caaccaaaca aatcaaacaa ccaaaaaaca
    32221 gtacaaacaa caaaggccgc aacgcaggaa agcagcagaa gcggaaataa aaatatatga
    32281 caaaaaactg tagacaaata aaaaaatttc tttgttctac agtttttttg ttacaatcaa
    32341 agaaaacgtt cgcttttcga ggagggatgt ataatgatgt tcaaacaatc aatggatagt
    32401 cgaatggaag aagacaaaat ttcgctagat gcacttgttc ctaaaaatca tttagtccgt
    32461 aaaattgaca agttattgtc atttgatttt atttatctca ttgttgaatc aacttattcg
    32521 accatcggtc gacctagcgt tgatcctgtc gtcttagtaa aattagtatt cattcaatat
    32581 ttatttggga ttcgttcgat gcgtcagacc attaaataag tttaaacaaa cctagcttat
    32641 cgttggtttc ttgggcttag tttaattgat aaagttcctc atttttcaac ttttggtaaa
    32701 aactatgcac ggcgtttcag agaaaccgat ttgtttgaac agatatttat cattattctg
    32761 gaacaagcag ttgttgctag atttattcat gaagaaattt tgtatatgga ttcaactcat
    32821 attaaagaga atgcgaaaaa acgtattttt acaaaagata tggcacataa agaagccatt
    32881 ttataccaaa aacgattgga agaagaaatc aatgaggcaa gaattgccga aggcaaacgc
    32941 cattttggtt caatcattcg tcaggaggtg gtcgaaagga aatttagcgt cgcagatcca
    33001 gaaattggtt attatgtaaa aacagaacga gaaaaacagt ttgcttattc ttctcatact
    33061 gtttgtgatg aaaatggttt tgtattagat gtcatgatta cgcctagaaa tctacattac
    33121 agccgaatgc tcgtgccaca aatcgaacgt gttaaatcac gttatggtgt agctgctgat
    33181 gctgcgtaca aaacaccttg gaacgccaag tatttaatcg accgaaaact acgacccact
    33241 tttccttata ctcgacccaa aggaaacaaa gaacgtttta aaaagaaaga ttttgattat
    33301 gatccctatt ataactggta cctatgcccg aatgatcaaa cacttcagtt tcgcacaact
    33361 actcgagatg gctataaaaa atatgtatct aaatctttta tttgtgaaag ttgtccatta
    33421 ttgaaaaatt atacagaaag ccagaaacac caaaaagaaa tacatcgaca tatttgtgaa
    33481 gattacttag atgaagcaga acatttacgc catacggtgt acaatcgcga aaaatataaa
    33541 aaaagaaacg attgaacgca tttttgcaga cgcaaaggaa aagcatggag tgcgctacac
    33601 caagtatcga ggcttggaaa aaatcaggtg catacgatgc ttgtttttgt cgcaatgaat
    33661 ctgaaaaaat tagccacttg gcagtgggag catatgtctt tatatctttt attatacaaa
    33721 aatagacaaa agtatcagtc tacactctta gtcaagagga aactgatgct tttatctaca
    33781 gtctgagaga gtgggacaat agtcctttct ccaaaagaaa acaagtccga ctttgatagt
    33841 taattttaaa atcggacttg ttttttcttc tttacgtctt ttcctctcca tgtatttccc
    33901 taattttctt aaatttaacg ccatgagtgc caagccaatg ttaatcttgg ctccttgttt
    33961 ccctcgtaag tggaaatccg tttccgatag atcgaacctt ctttttcctc taaaaacttt
    34021 ttttacattc tgctttgaaa taacgccatg tattattcac taaaatttgt cggtttcgct
    34081 cactttttgc tttcgtacat tgactacgaa cagggcagca ccaccataag ccgcctgcca
    34141 gttacctctc actcttaccg ggtctttcag aacacccgga tgctctaaca catcactcgg
    34201 ctaggctccg ttattgaaga agaaagcccc atatctttcc atggcatcct cggccagctt
    34261 aagaagctcc tccatctgtt cggagacctt cctcacatat atgggcaaag gccatgaaga
    34321 cctccaccag actgttcatg accttcttca gtgctgcgat catctgctct ctcttctcca
    34381 tggcttacac ctactcgaca gaatcagcgg catcagaggc aagagcatcc ttcatgtgct
    34441 gtgccaggaa gtcatccagc tggttcatag aaaaatcgac acccttgttc atggcctcgc
    34501 tgatttccat cagcttctgg ttcacctctt cctcagacag gccggtgcgc tcacagatgg
    34561 aatggagcag atgatcgtgc atctctgcca tcttctggtc catgtcgaat ttttcgtggc
    34621 agcaatctct gcgccatgcc ttcggaaata cggcttcccc ccctcatcag actgtgtgtt
    34681 tggttccagc tctttcttcc gggattcttc gctctcggaa atcggtctgt acagtgaaca
    34741 cacataaata ttcttcctat gactggtatc actcatggct tgtctccttt atttgttttg
    34801 tcgagtccta cctcaaagga ggtctggcca gcatataggt gttcatctga ctgtcccttt
    34861 caaaattagt gtcctcatct atgatttcgg gcgttttata actcctccgg acaaaatttt
    34921 tgaaaaaatt tgtcgagggc ttaatacacc tctttcataa ctgcaaacgc acgcttcaag
    34981 gtcttggtga tttctgcatg cgacatgcgc agatccctcg caatctgctg ctggttcttg
    35041 ttcaggaagt aataatgctc gatgaccttt ctctgattaa aggttagctt ctggatctct
    35101 tcttgcagac gcttacgctc catcttctta aaatcagtcg gagcaatctt ctccacaatg
    35161 tcaggagtat aggacatcat gcagtcctgt gtgtagctgt cctcgatggt ctgctctatg
    35221 cctccgaggt atcttgcata gttggattcc agacggttct ctgcatcatg gtcatgtaga
    35281 tggtccactg atagtccata tactcctcaa ccaggatgaa gctattctta tcggcgaacc
    35341 gatacaacat tccattcatg cggtcagctg tgaagatgga gtacatatca ttgcgaatat
    35401 agaggataaa gtcgttgcga tacacggtca acagagaatc gtccatctag aactgagcca
    35461 cactcacttg gcaccatatt atcactcagc taacggaagc cgggctgctt tacgcctttg
    35521 gtgctgtcct tgatttcctt ccatatactg cttgccgaga ttgatgattc ttctgacatc
    35581 gatcaaagta acaggtaatt tagaatcttc cacaaacctg attatctcct ctactacttt
    35641 cggctcaata tcttctaatg cgatcacgat tttatatacc tgctacttca caataacatc
    35701 ctgaacatca gatattcgtc caaaatactt taatttcgcc aatccatccc cataattagc
    35761 aaatcctggt tcttcaagta gaatatcctc tttctttcga tctttcacat atccaataat
    35821 atttgcatct gcgtctggat ctgataacat ggccaaacca tattctttag ccaggtttcc
    35881 attttccaca accaaaactc gagtatggga cttgctgcct atctttttca gtaaaaactg
    35941 aaatacagca ttcttgacga gcaacaaaac gcacgatatg atccaaaata aaagcaatgg
    36001 ccatttggaa aagtatttca cattagcgat atataagtat aagaaagcaa ggaagaacaa
    36061 acttccaata ccggttaacg atactatttt aaaaatccgt tttgatactt tctgaaatag
    36121 gtcttattcg ttgcacgaaa aatcctcaaa aaatctgcaa tcaaaatact atatagcgca
    36181 gccatcatca aatacggaac tgacaacata ttgatcccgg gagcagcttc taaaacgtgg
    36241 taacaaataa acatggccaa tagataggct acaaaaatag atgctgcatc tccaatacag
    36301 tcaaaaactg tgttccaaaa tcgttccttg ataatttcat tgattctccc cttataataa
    36361 tatcgaatgc tccaacatcg gtcagaatca tctcttctgt ctatcattcg ccacgtagaa
    36421 gttgttggaa aagagtgaca accgttcaag acgaacggct atattgtatt aattattctg
    36481 tgtatcaact aaccactcaa caaattcacg cactgcacca ttaccaccat catgttcagc
    36541 gataaaatct gaaatttcta gaaccttttt aactgcatcg tgcggacagg ccacaatacc
    36601 acctgcactt ttaacaggat gcatacaaga taaatcgttt atatcgtctc caatatatgc
    36661 aacagtactt agatcactag taatctcaag cagtttctct attttattgt ctattccctg
    36721 ataaagaatg ttgataccaa gttccttaca tctattttct aatattttgg aacgacgacc
    36781 agtgataata ataggctcaa tattatgggc tcttacaata tcgtgaatag cgcaaccatc
    36841 tttaatattg aacgccttca taatttcccc acactcaccc atatatatct ttccgtctgt
    36901 tagagtacca tcaacatcca taaccagaaa tttaatttgg ctcatacact ttccccccct
    36961 ttcaataatt gatagaaatc ttaaatacag ctttctttac tttagctgat tcattcactc
    37021 ttatgcaagg catatgagca tcctcaggag ttagtagcag cagcttccct ccttctaaga
    37081 gtacacaatt gccaactatt gaattactgt aaaacacaat atccttgtca gctgaataat
    37141 ctacttcaat ctgtaaatta gatatagatt ctactacaat atactcgcat cctaagagaa
    37201 tacattgaat gtctaaatat ttcaagtgag attcgtacat tctttcttca aatctatata
    37261 tatcatagga ctcaacattc agataaattc cattggaaag atcatatcga ccttcttcta
    37321 attccaacaa ggaatttttt ataagaaaat atagacttct ggaaattcaa tttccatttt
    37381 tttagactta actttttcat ttatctcctt tatgcaacaa taccagcttt tacaatttgc
    37441 tgccatgtaa tggtaccaac aagcatacct tcatcatcga ttataggaag aatgttaata
    37501 ctattagcct ttaaaaatct caatgcatcg acagctaatt tatctttagt aaatactttg
    37561 ggattagcaa tcatcacatc atcaatttct acagaataga tatctacttt tctctcaata
    37621 attcgtctta aatctccatc agtaataatg cctttgagag ttccatcctg atcaatgact
    37681 gaaactatac ccaacccttt attcgacata acagaaatag catccattaa caatgttccc
    37741 gaattgacca ttggaatctc attgccgtgg gacattagat cagacacttt aagtattaat
    37801 tttttgccca atgaacctgc gggatgaaac tttccaaaat cagaatcttt aaatccataa
    37861 ataccgctag caacaacagc taatgcatcg ccgtaacaca acacacttgt agcactagaa
    37921 gttggagcca atcccaaata gcaagcttcc tcaaactccg gtaatatctg gacaatatca
    37981 gatgcggtag caagcgtaga ttttgaattg cctgttattc caattaaagt agccccaatc
    38041 attttaatat taggaagaat tttaacaatt tcatcggatt cgccgctata gctgatagca
    38101 attacaatat ccttttctga aaccatacct aaatctccat gcatcgcttc agcaggatga
    38161 agtctgaatg ctggtgttcc taagcttgca aatgtcgctg ccagcttagc agcgatatga
    38221 cctggctttc ccataccagt gataatgact tttccttcgc aattaacaat tgcatcaaga
    38281 atacgaacga aagtcttccc aagacaatct ctcgttcttt ttaaggcctc aatttcaata
    38341 tcaaaaactc ttttggcctc tattatctta tccattttat ttacctcttc agtttttaat
    38401 agcagctgga ggtctttcac atgttgtaac acagtacaaa atgtgaaaga cttaccatac
    38461 atttctatgc aatgcaagaa aaattatcta acggcattgt atacttttag tacacgctct
    38521 aataacccct caaattcatc caagagaacc atattcggac catcagacaa ggcattgtca
    38581 ggatcaggat gtacttcaaa gaacaaagca tctgcgcctg ttgcaacagc cgccttcgca
    38641 agaggctcaa cgttatttct attacctcct gtaacatctc cttttccacc aggcttctga
    38701 acactatgcg tagcatccat aacaacaggg taaccaaact tcttcatctc aacaatagat
    38761 gtcatgtcaa caaccaatgt attatatcca aaagaagtgc cacgttcgca aagcataatg
    38821 ttactattac ctgcctccac aagtttatta ataacatttt tcatatccca cggtgcgaga
    38881 aactgtgctt tttttacgtt aattattttg cctgtttttg ctgctgccac tagtaaatca
    38941 gtctgtctac acaggaatgc aggaatctga agtatatcgc atacctctgc agccttttct
    39001 gcttgccaag gttcatggat atctgtacaa attttcaatc cataagtttc cttaactttc
    39061 ttaaggattt tcaaaccctc ttcaatacca ggacctctgt aagaggtaat actagttctg
    39121 ttagctttgt cgaaagaagc cttaaaataa taatcaatat cgagcttctc cgtaatctcc
    39181 ttaatagtct tagctattaa cattacattt tcttcggact caataacgca tggtcctgca
    39241 attaacataa gtctattcat cttatagacc ttcctttctt aattcatctt ctacctgctg
    39301 tatctgctcc ggcgtatcca cccccacggt ttgatattta gtttccttta ctcgaatctt
    39361 aaatccactc tccaaaactc gaagttgttc gagagattca gatacttcaa gaggcgtttt
    39421 gggcattgta ctgtatttct tcaaaaacca tgttttatac ccataaacac caatatgttt
    39481 aaaatgcaga gaattttttc catctctttc gtatggaaca caaaaacgtg aaaaatatat
    39541 cgcataatca ttgacgtcat tgattacttt aacaacattt ggattgtcaa gttcctcctg
    39601 aacttcaata tgttttttca aggttcccat ataaacttca tcgttatcaa agcaagaata
    39661 caaatctgct atcatctctg ccttgataag gggctcgtct ccttggatat taagaactaa
    39721 gtcttcatcc cggagttgaa ggatctctgc gcactcagca agacgatctg tgccgcaagt
    39781 atgtttatca gaagtcatca aagccattcc accaaagctt tcaacacagt caaaaattct
    39841 cttatcgtct gttgcaacat atactgcatc tagcatagct gccttagaaa cattttcata
    39901 aacccactga atcatgggtt tactagaaat catagcaagc ggcttccctg gaaacctact
    39961 tgatccatat cgagatggaa taatagctat tgtcttcatc ggttctttct ccttttaaga
    40021 taatccatta acaacttatc tttcatacat attagtaaaa tactatatag taaaatacac
    40081 aaaattactg taatgaacgt tgatattact gaatttggga gcttactact gacatatcct
    40141 ccgacgcctc ccataatcag tgcacctatc aaatagtttt ttacattcgt aataattgat
    40201 gccattttta attctataca gtttcttact tcataaaact gaattgcagt aactgtaagt
    40261 tcagcaaata ttgtacctat tgcagcgcct atagcttcca aatgtggtat taaagccaaa
    40321 ttgacaacga gattaatcac agcgcccgtc ataatagaga aggtatacac cctttgtctt
    40381 ttcatgggaa tcaaaacagc ttgaccaacc acactagcaa atccaattat caaaatcaat
    40441 ggtgatagta actgaaataa ggaaactgac ttagcgtatc cgtctccaag aaaccacggt
    40501 ataaaagtat ttgcgattat aatcgcacca actaccattg gggcgcctat gcaaaacaca
    40561 aatgatactg cattcaatac ttcttttcta attctatcaa tattgttttc tttaaccgct
    40621 actgcgatat gtggcaacat aactgcacca agagatgtaa tgactgtcat caacagcttc
    40681 actatttttt caggctgcga gtatagccca acttggacat ccgtagaaaa tattcctaat
    40741 ataatcttat taacatacgt atagatatat actgccgctg ttggaagaaa taatcctaat
    40801 attggtcgaa tatggggtgt tatcgatata tcatgaatac ttattcttct aacatatttt
    40861 ggaatatgac aacataataa tgcattcccc aacagctcag ttccagccaa tataactgag
    40921 tacaatacta catcattttc atttttcacc aataagaata tcaaaacaag accaattaac
    40981 ttaaccacca tacttctgat tgcagttttt ttgaaatctt ccatcccttg gaaaaaccaa
    41041 ctgacatcaa aaagatttgc aactaaataa acagacatac ttattagtaa aacagtgtat
    41101 gaatgaagag tagccgaaat aagaatatat acaggaaaaa cgataaacga agaaataata
    41161 cggataacaa agatgctcca aaacactcca cttcttctga tcttatcatt ctgaacataa
    41221 gcaatctcac gttgtccata catgttcgta cctaattgag caattattac cgctaccgat
    41281 acaatggcgt acgaataatt aaactcccca actccctccg ctttcaatac tctagatacg
    41341 tatggagtcg taataatagg cagtatcata accaaaattt ggtaacaaag attataggca
    41401 taatttttga tcaacctatt catattactc ctcctttatc ttaaatataa tttcatcctg
    41461 ccttttcgta aattctcgta ctaaaaggca agcaaccaca acagaaaata tatttgttat
    41521 agaaaacgcg aaacacatct ggcaatagta gaaactcatc actggtatgt aaaagaagta
    41581 tgccgtaatt agtatatagt atttccttct tcttctgttt ttttccttat taatgcgaat
    41641 atgaatattc caagaaaaaa tccaaaaaac aataaaagta aacaccagca tacctaacca
    41701 accaaaatca gagtaaggtc gttgaaacca cgaaaattca ttccccgcaa agttactatc
    41761 tccaccaaca tggatatatg cgtttttaaa ttctggttct ataccaaaca tctctaccaa
    41821 tgaggtaaga ctttttgccc cccaattcaa ttctggagaa tatctctgga gatatttatc
    41881 cagcatatat actgggcttc cgatataata agtaatatag tctgaaaact ctcttgttgc
    41941 cgcagtcgag ttaacttttg taatacctct taatgcataa aatacagcca aaatcgctac
    42001 tgcaacgaat aaagtttttc gcacaacttg cataacagga actcgtccac gaggcgatac
    42061 atctgacttc attactatgt atatcaaaaa tactatagca aaaagcttaa ctaaaaacac
    42121 acggttaccg gatataaaca tacataaaat atacattaat gttggaaaca agtattttat
    42181 atttgataaa acacgttctt tgcatctaat tacattattg ataaatacat acaaatatgc
    42241 aaggtttaat cctgtaatta aactgatgcc aaatcttgca ataactgagt tctgcgtttc
    42301 atctgactta gctgctccaa ttgcatataa tcctaaagtg ctataatcgc cttttcttaa
    42361 tatttctacc aaaagaacac caaagaacac aacagataat agtgcaaaaa ttaaatttaa
    42421 ttgtctgcta gggtaaattt gtacatattc aatcttatat tgattttgat ggtaattatc
    42481 cactcttttt tttgataaat agtctaagaa taatatatac atttctggta tacacatagc
    42541 taagaacccc gtcgtaataa accagagcgt cttcttgcta tattgcacat tccaaaattc
    42601 gatattataa accacacagc atgtcgccaa aaaaaacaat gcaatcgcga taaatgctgg
    42661 tgatataaaa catcgattag acaaaatata cattattaaa attagtataa attcaacaat
    42721 caataattga taaatcattt attcttctcc taatattttc tttcggagaa tctccaaata
    42781 ttcgcatccg aaaaccaaat ctggctccat ataatttcct tctccccact cattccaagc
    42841 ctgaagaaat agtatccgat gctctggttc cttgtcttga acatacgaaa gtgctcggtc
    42901 tattgcattt ccaaattttt ctggagtact atcaacatac actcttgcat ctttaccaga
    42961 tcgtggggtt cgatctaatc ttggaatcaa ctgaggatgt acgcactctc tcttttcttc
    43021 ttcacaataa aaattctcca ttatcttatc atatggatag agatttgctg aaaaattacc
    43081 aactgtcttt cgcattatgc tcttaatacc tcttttccag tatcctgaaa tttttaattc
    43141 ggcatatctc tgcatatcag aatttattgc gtcatatccc atatcaagga aacgctgaaa
    43201 tctattatgc actgctacat ctgtcataga tgacaaatcg aacttattat caacagatgt
    43261 tactctagcc acaaaataga taccttcaaa tccattctcc ttagcaagtt tattccatag
    43321 tgaaataaaa tgagcagaat ctggaataga atctggagca aaaaccaaga ataaaggttt
    43381 accatcaact tttatatatc tatcatcctt caatgccgga agaatagatt taaagtgaag
    43441 tatatagtct tcatcaccag gatatgtttg ttccaaaaac acaacatcct ttgtgaaatg
    43501 ctttgacttt tgccaagttt tatttgacca tgaatgatta gcccaaccga gacaaaaagg
    43561 aaagtcaggt tctccgctct gtaacacctc attaaatgga agttctagaa ttctcttacc
    43621 attgccaaac caataatgcc aatagcaaaa accctcaacc ccatatttct tagccatctc
    43681 agcctgttgt tttcttactt ccgagattct taaatcatag aaacctaaat ctgcaggaat
    43741 ctggggttga taatgattct tgaatagagg tttagcttta gcaacattag tccattcagt
    43801 aaagcctttt ccccacatta tatcgttttc acgaacagga tgaaattgtg gcaaataaaa
    43861 tgccagtacc cttgcttttt tcatttaact gcctcctcta aagtaatacg atcaaaccaa
    43921 ttcagttttc cgccacgagt tgcgttatat atttttatgt tattactttc gcaaaactct
    43981 cttgctctta tatatgcctg attcattcca acaatacttg ctattacttc atttgcattt
    44041 ttgtcttcaa aaaaatgact tctaatggtc ttatcttcag acactgttcc atcagcatta
    44101 taagtcagtg cataactatg atccatacca agaagatata tttttttata tcccatataa
    44161 acagcagctt gaatcatcga ataagtaact gtttcatgcg atacaatgga tttactgata
    44221 tcctcactaa acttaatatt tttgccacca acagattgct ctgagtgaat acatatagca
    44281 tttggattat gcattcctct aactctccaa taataatccc caatgaacat gtattctaag
    44341 tcaatatcat ctaattcgtt accagtatct gcatatctat cctggataaa ataatattta
    44401 ggtctccact gggttttatc aaaaatctta aaaataagat tagcagcaaa acaatcctta
    44461 tcctttatta attccaaatc ctccattgtg agacttggac cattacctac aataaaacag
    44521 gtctcaccta aaaatttatt tctcagtttc tcaattcttt gaatattatc tgtattcttg
    44581 cagaacttat cgtagaagta tttgttttga acatcaacca caaatctcat tagctttaga
    44641 ataggcggaa ttctatgaat cacctttcta atttttatat ttaccatatt tactccttcc
    44701 gaattacaat atcaaccaaa aattcgttat ctaattaaat gtttactatc tctggccttt
    44761 ctcactaata ttcaatggag tgtcatcttc gaagatatac ccttcagctg atgcattacc
    44821 tttatattca ccaagtacct gtggccattc aataccaatc tcaggatcat tccaagccaa
    44881 gccgccctcg tcatttgcgt gatagaaatc atcactagta cctttcacaa cgatattcct
    44941 ttctttatta aacttttatc aactacgata attcaacttt tgatcgagtc ctcatcaatg
    45001 atactcttaa ttacatgagt caactgagtg ctggaaatac catctgtatg gggaagataa
    45061 acaaattcaa caccggttcc cataaactgt tcttcatatt tttcctactg aggattgcct
    45121 ttctaatcag aacccacgaa cattttgtta aatttatatt tctcccatgc cgcatactta
    45181 tccttatcat tttgagggac aaccatatcg acatacttta ttgaatttac aatttcggct
    45241 cgttctacat acggaataac aggtgtctta tttttatctt actaaaccgg ttcatctgta
    45301 ctaacaccga caatcaaaaa atcacattgt gcttttgcat ttcgcataac attcaaatgc
    45361 ccaatatgaa acatgtcata tacacccgtg gtgtattcta taactttttc tttcataaat
    45421 atctccttta actgtgtatt tcagagtaaa ataggaatct ttctcatcaa tctgcatcac
    45481 actctacatg tccaaataac atagaccgaa aagtcaagaa agataatttt ccagtctgtg
    45541 atgaaccttc tctcttctac atacttcaca tagagttcca ttcattcttc gaaagataaa
    45601 tcatttcgac gcgtaacaat cattaccatc gaacaaaaac gttgaaccac atacaacagg
    45661 cacattcctg cggtaatttc tttaatgttt tttctcctga gtcttcactt accccgatat
    45721 agttaatgcg actcaaaaaa tttcttgctt tcatcgttaa cctctctttt taactaacat
    45781 ttcaaacaat accgcatgtt ctgaagctac ccttttggaa ttatactttt caagcactac
    45841 cgatgtagct tcggaagtta gccttgcagc cattgcttta tccgaaaaaa tcttaaaaac
    45901 tgcttcgcaa gcagccgtct catcatcaac gggcaccaac aatccatttt ttccattgct
    45961 aatcaaattg ggaattgcat caatattggt ggcaatgata ggttttccca ccatcatgta
    46021 ctcaggcaga gccaaaccaa atccttccca acggcttaat aaacatgcaa catcaaatag
    46081 ttcaatatag cttatcgaat tatttaccca gcctgtaata tgcagacttt ccaaaaaacc
    46141 atgttctgct gcatatttct cgataagtgc tttttgctct ccattaccaa caataatgaa
    46201 atgggcctct ggtattttat tttttaccaa tctagccatt ttaatgaata tttctggagc
    46261 cttctgcgga ctaattcttc caaccatacc tacaacaaac gcatcttgtg gtatattcaa
    46321 actttctctt tttacctctc catgagcttt atttctatat gcctcaatgt ctacgccatt
    46381 aaaaatgacc tgcaacttat cttcgcaaca aattctcttt ttcagtgctg attgtttctc
    46441 ggcatctgat atacagataa ttttatcgca aaacagagca gctatttttt ctatagcagt
    46501 gtatagcatt ttcttcttaa ctgagcacct catgttgaat gcccatccat gtggattgta
    46561 tacgcaatag ttcttcaaac caattttagc aacacgtgta atggctcctg ctttactcga
    46621 atgtgcatac acaatatccg gattatattt ctttatcagc tttctaataa ttacgattgc
    46681 ttttaggtca ttgagatcaa tttctctagt caatttaatt tgcttaaatg agagcacaag
    46741 atttgcataa tccgtctcgc aaaaatcttg cgagcaaatc aatatgtttt caaacttttc
    46801 cttatccaaa tactttaaaa gcatgcgaat ataacaatct acgccacctg cagcttgggc
    46861 aatgtgtaaa actcttattt tttgacgcat ttctgtcctc cattttactt atcataacaa
    46921 acagtatatc tcgaattacc agaaaaataa tcttccaatc agcaaagaaa actctcttat
    46981 actacttcac attgatctcc atccattctt taaaggaaag ttcatttcaa ttcagagcaa
    47041 tctgccaata atagctaaga tcaggctgta catacaattg ctgtctttca tagcctccat
    47101 actgcttcat ctttctcagc aatccagatt tgggacccac gatattcata tcttccttga
    47161 aaatattcca aatctgagga gattcatcat ccacgaacac gaaacgaaac ttatagaact
    47221 tgaacaattt accatttctt ccaactctat cttgtgcgaa aacaggagtc cgccggatca
    47281 tcaaacacaa taactaacgc tgtaatcagt atcacaggac acaaatagca agtgttaaaa
    47341 tggaaaatat gaatacttct ccaatatacc cggactagat aactcccttt tgttcataat
    47401 ccctcatact catcagattc accaaacttt accgtttatt tttttcaata gttcaccaaa
    47461 tgactccatc taacaaggtc aaatataaaa aattaacgca ttttcattat cttttaggca
    47521 tttattaatg gagatattta gtgtttttat aacataataa atgctcaatg agagcctatg
    47581 ttgggtacat caatattaaa gtattcagca ctaatatgtt taagatcgat attatatatt
    47641 tcataatttt gaaaattttc tttcatatag gaaacatgat actgaattgc tttagtcacc
    47701 tttctttttt tagattttct acaagtgatt caaaacttcc ataattacag ttattacttt
    47761 tgaaacgata atatgaacat gtgtaatctt ttttatcaac aatctatcaa ttctatccct
    47821 tactaatatg ccccatttgg ttttataacg atccaaattg tcttgataat tagtttaaaa
    47881 tcattcaata gactttgatt agttatatat tctaaatcta aatcaaccat tgcatgaaaa
    47941 ctaacatcat ttctaccact aacttgccac aaacctgaac atccaggttt tacatacaag
    48001 cgttgaagat catatctcgt gtactcagct acttcccttt ccaaaggtgg acgtgggcca
    48061 actagactca tatctccttt taaaacattc catagctgtg gcaattcatc aatgctttta
    48121 gcgcggataa ttttacctat ttgggtgaca cggggatctt ctttcatctt gaacattgcg
    48181 ccttctattt cattttgatc aagtaactct tccaattttt cttcagcatc taaacacatc
    48241 gaacggaatt tatacatttt gaatgttttt ccatttttac caacacgtgt atggctaaaa
    48301 aatatcggac tccctggctc ttcttttctg attcgataag ctgcatagaa catcaaagga
    48361 gaagctaaaa tcaaaccaat gatgcttcct acaatatcaa tcattctttt aaaaaataaa
    48421 tagatatatc gtttttcaac tttttcttta tccaaccaaa cttgattagg atgtacttta
    48481 ctaatacgag ataataaatc ttcactttcc atactttcag tccctttcgc tctctattca
    48541 tttccttttt atctacgaat aaaaactaaa ataaaccaaa cttcttcttt tttacctctt
    48601 catatattgg ataactgatc tcatccccgt tgatcagatc ctttgcgact tgcttcatct
    48661 gtactacttt ttccttacca aagtccttgg caatctgctc atagcactct tttaagtaaa
    48721 aggtgcgctt agagacccca tgggcatcag aagcagccat ctgcacgaga ttatgtttga
    48781 ccatcgtttt ggctgttttc tggatatctt tgccaaatac cccaacataa cttggcgcag
    48841 tgagttgcgc caaacatccc atatctagga acggaagcaa atgattcggg tcttcgcgaa
    48901 aatgcgcgtt acgttctgga tggacgatca ctggtgtctt tcctagttct aacaactcaa
    48961 aaaaaagctg ctctgcatat aacggcactt ccagtgtcgg aaattcgatc agaagatatg
    49021 tatcatctaa atctgtaaat aaaatttcat ctcgctggat gtcttcaatg agcgttccgg
    49081 taatacgtac ttcttgtcct tccaataacg tcaaaggcaa ttgtcttttc tctaattctg
    49141 cttgtaacga agcgactaga gaaatgactt gtgatttttc attgctgtat tttccattat
    49201 tgtggtgtgg cgtgcataaa atatgcgtga tgccttgctg aatcgctttt tcagccatta
    49261 cgatacttgc ctctaggttt tccgccccat catcgattcc tggtaggata tggcaatgta
    49321 gatcgatcat ttctcttgcc tcctctcttc ttatttctta atttccgtag taataaccat
    49381 cgtctttgct gtgttctgct ccgttgtata caacacctag gactcgtgct tgtaccatct
    49441 ccaacagctc ttttgcttta gtcaaggatt ctttacgtga cgtattttca cgtaccacca
    49501 ataaggtgcc atccgttttt gaagacatga tctgtgcatc tgttacggct actattggtg
    49561 gcatatcaaa aattaccacg tcaaataact gtcttgcttc tgctaggatc tgatccattc
    49621 ttggcgaact taacaattct gatggattgg gtggcttagg tccactaggc aaaatcgaca
    49681 agttctcgac tggcgctcgt tggatcacat ctgctacact tcctgatgaa ctaagtgctg
    49741 tacttaatcc actggcattg ttcagctgaa atgtcttata gatgacgggt ttacgtaaat
    49801 ctgcatcgac tagtagaact cgttgaccag atttagcaaa aacgactgca atgtttgatg
    49861 cagtggtaga ttttccttct ccaggacctg atgatgtcac gacaatcgtt ttgatttgct
    49921 gaccagttgt ggaggcaaat tggatattcg tccggatcgt acgatattgt tcggcgattg
    49981 gtgaagatgg gtttgttaac gtgatcaaac tgactgcatg agttggtgtt gctttttgtt
    50041 tctgtgttcg tgccattttt cttccctcct aaactcttga gcgacttctg cgtgatgagg
    50101 ctgttttatc gtttgtaact tttggtcgtg taggagccag tcctttttta cggataccag
    50161 ctttcaattc tttctctgac atttctggaa ctgttcctaa gattgggaac cctaatgtat
    50221 ccgtcacata tttttcatct ttcactgttc gatcgagtaa ttcaaataag aatgccagaa
    50281 ctacacctac catcattcct aacattaagc caatcactag attcaattta ttatttggcg
    50341 aaataggtgt cgtattggca actgcacctg aaacgatcga gattttatca acattcatca
    50401 cgtcttttgc attctcttgg aaaacttgtg aagttgtgtt agcgatctgt tgagcagtca
    50461 ttgcactcgt gcttattgct tgaatcgaga acatttgtga attttctgat tgattgattg
    50521 agatggcatc cttgatttgt tcaggagtca ttttcacgtt gtcttctgtt ttcaaacgtt
    50581 cttggacttc atttagcact agatcactga cgatcatatc tttatacgta ttgatcattt
    50641 gcaagttcgt attgacatca ttgacatttg cagtatctga ttgcggcagt gtcacaatca
    50701 actgtgcttg cgaactgtat tttggcgtca aaatgaaaaa cgttacaatt cctgagatag
    50761 ccaagccagc aaacatcgag atgatgattg ttatcaagtg tttgcgtaat gtttcaaaaa
    50821 tttcttccaa gctgattgtc tcttccattt tttctccact ttcctattta ttctctaaat
    50881 tcatttgttc ttttaattct tttttcacac gatcaagttc attgtcatta actttttgat
    50941 atgagatgtc atcttgcatg aagccttctc cttgcatctg atcttgcttg atcgtatcaa
    51001 atgcttcccg ataatctaaa gcaatctttt tcatttcatc aaagctcatg tctgttttca
    51061 tattcgactc tagagcattc aaaatggatt gatagttgct gacaccattt agactcaata
    51121 ctttttttgc tacgccttct acgatctttc tttggcgccc ttgtctaccg taatcaccat
    51181 ttgggtcttc ataacgcata cgagaataag ataatgcctg aaccccgttc aatgtaattt
    51241 taccgattgg aaagtcatag ccatcttgtg agaaagtgag gtcattattg acttcgatac
    51301 caccaactgc atcaacgagt tcctttagcc ctttcatatt gatagagaca tagtgatcga
    51361 ttgggatgtc tacatatttt tgtacggtat ccatcgccat ggcagctccg ccgaatgcgt
    51421 aagcgtggtt gatcttgtct tttgtgtcac gacctacgat gtcgacatac gtatctcgag
    51481 gaatgctgac gatcgttgtc tgtttgtctt caggactgac tgtggcaacc atcatcgtat
    51541 ctgatcttcc ttgatcgacc cgacctaaat ctccagtatc aatccccatc aatagaacag
    51601 agaaagattc ttgtttgttc agatcaactg gtttcgttcg ttctccttgg gttcgttcca
    51661 ctgactcgta agttttctca atagaatgtg agagatccag atataatttt gctcctactc
    51721 ctacaattgc taatactaat acgataagaa ctgctaaaat aatcagaaat atttttttcc
    51781 ctcttgattt tcttcttcgt cttgccatag tttcctccgt ttgctagctt tgctttaatt
    51841 gttactaact tatattgcta tagcccattt gctgagcaac agtttgtgct tttgttgcgt
    51901 atgctgcgcg tattttttca ttccggatct gctctatttg actgagcacc gtcaaatatt
    51961 gatcgtaagt agcggtggca gtcacttgac catccttcaa catcgtatcg aataactgat
    52021 ctagttgcgt gacttgcgcg atctgagtat cagcgaatcc tagatattgc ataacaaccg
    52081 ttttccaagg actatcttta aaaaagctca tattttcacg tacacgagcg acatctgcac
    52141 ttgtcacctt ttctttgatg acgacatcgt ctacagcttg ctgccagttt gatacatttt
    52201 tagtaaataa atcgttgaca gctgtctgga tcttcagttt tgattctgca tcctctaact
    52261 gcgttaagac tgctttcttt tcttcttgga tcgcagcagc ttctttaggt aattctgatt
    52321 ccttgatgtc ataatcatct gccgaaagtt tgatagaaga tagtttatgt gacaaatttg
    52381 aaactgtttc ttctgttatt tcaggattta ggaaaatttt ttcttttgta ctgtacagct
    52441 tatctacttc ttttgataaa gaggtcacgg tgtctttttg attggtgatg gcagattctg
    52501 cgtaattgat ccgttgatga tgttgccgct gattattgaa atggtatcca aacaagcaaa
    52561 tcacaatagc gcctgtgcct accgccacag tagccaataa cttgacgaac ggcttttcca
    52621 tagattcact cctaaatatt gatgatagat aaataaagat gtgattcatt cccatcagaa
    52681 tgagcgcttt ttattttaaa agcataatta aactaatata ttcatagaaa tatttataaa
    52741 caggttttcc ctatataatc ataccacaaa aagttttctt gactagggaa attcctaatt
    52801 taaaagtaaa taaaacagta acaagatcat gattaatcgt tttcattttt atttcctctc
    52861 ttttcatgag cattttgaaa attcgaacaa agaataaaat aacaaaaatt attaaaatag
    52921 aattaataac agctatttat atttataac
//
LOCUS       DAZKKZ010000013        51951 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.013, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000013 DAZKKZ010000000
VERSION     DAZKKZ010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 51951)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51951)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51951
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.013"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            89..1549
                     /locus_tag="ACG8LA_000815"
     CDS             89..1549
                     /locus_tag="ACG8LA_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0203134.1"
                     /translation="MLENYIERNIFRKVYLCEQLFEFQEIDIEQTAISLRVTTPTILH
                     DLESLAECLEYCIKEQVREKHKYKLVFKHGIALSELTQFLYGQSYFLKFLSYYFNGIF
                     TSTELADLEFISLSKVYTIKKIVLDFFKENDYLKNKEIIIPEFDSRNILLALVRYVNW
                     EGYENKNPYVEEACNELIDYVETHFFKRRYSEDEKSFIIRGIEIAIGRKAFPLGLKEE
                     DKKSAETKPLFQLVCQGLEEQKGILDLQEEDVYYIFSLFNSRNYTNENMELLRKDFEV
                     VYKNFVLNDLSLNELILQIISIAEIDDAENFIFKQSFLQFVRTLWADGQVFLPERIYL
                     LSEKEQLLYGKIVEILEEWKKKNQIQLRWNENFIRKFVKSLSLINSEQAGRQEIEIFV
                     VSESSVKQFFYRTQFHLYAEEGIAEINPILFRSLEELPDECLCAKKRVVLCDAASYQN
                     GLETEKTKIYPISLKGANIHLYHIAQELHLLKKHIS"
     gene            1770..3533
                     /locus_tag="ACG8LA_000816"
     CDS             1770..3533
                     /locus_tag="ACG8LA_000816"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008661 - 1-deoxy-D-xylulose-5-phosphate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0016114 - terpenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HFQ0203135.1"
                     /translation="MSTVLHVLDAINSPADVKKLSVEEMKQLAEEMRQKILQKDSDVG
                     GHVGPNLGVVELTIAFHYVFDSPKDKIVWDVSHQSYGHKLLTGRKNGFEKGHYREVSG
                     YSNQHESKHDYFTVGHTSTSISLATGLAKARDLKKESGNVVAFIGDGSLSGGLAFEGL
                     NNGGVLQSNLIVLVNDNEMSIDENHGSLYKNLAELRQTNGKSSNNLFKAMGFDYRYVD
                     NGNDLETVIRLFEEVKDIDHPIVLHVHTEKGRGYQPAIDNKMKYHWHVPFDLSTGEAK
                     QVTSGETFNMIIMDYLDKKMQTSTAPIAAVNAAIPGAFGLKTFQEKHPDHYFDVGIAE
                     QHSITFASALASQGVRPVVFQSSTFLQRAYDQLSHDLAINENPVIILVGGGTISASDR
                     THQGTFDIPYLSSIPNIKYLAPATKEDMISMLDWAFEQTAQPVAIRIPTHGVEHGTAI
                     ANDYSIPAYQTVNNGGKVAILALGGFLELGKETVKAFRKKGIEATLINPGTITENDVE
                     TLDKLKETHELVITLEDGSLSGGFGENISRYYGDSSMNVLNFGAEKEFTDSVPVGQLY
                     ERYHLTPKQIVEDSLRVLNIQ"
     gene            3617..4075
                     /locus_tag="ACG8LA_000817"
     CDS             3617..4075
                     /locus_tag="ACG8LA_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HFQ0203136.1"
                     /translation="MYQQVEEYVKKFQEKYPSYQSEKLGFFSFGDTEKMADELSELVV
                     KKIKTGTSSGYDLYKQENEPLPKVGQLDVVLNGKNEPVCIIKNINVTILPFSEVTKEH
                     AWKEGEGDRTLAYWRKVHAEFFKHAYKEALNIEFTEEKLVVYEEFEVIFF"
     gene            4184..4867
                     /locus_tag="ACG8LA_000818"
     CDS             4184..4867
                     /locus_tag="ACG8LA_000818"
                     /EC_number="5.1.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009385 - N-acylmannosamine-6-phosphate
                     2-epimerase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006051 - N-acetylmannosamine metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019262 - N-acetylneuraminate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HFQ0203137.1"
                     /translation="MDTLEQIKGGVVVSCQALENEPLHSSFIMGRMALAAKEGGAVGI
                     RANTTEDINEIKRIVDLPVIGIIKRDYDGSEVFITATEKEVEELLETQAEIIALDATS
                     RKRPTEKTTAELVQMIHEHGRLAMADISTFEEALQAQEDGFDLLSTTLAGYTEYSRKT
                     QTPDFDLLNQIIEQVDIPVIMEGHTDSPEQVEKAYELGAFSVVVGSIITRPQLITKRY
                     VEAASKANN"
     gene            5014..5628
                     /locus_tag="ACG8LA_000819"
     CDS             5014..5628
                     /locus_tag="ACG8LA_000819"
                     /EC_number="1.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016646 - oxidoreductase activity, acting
                     on the CH-NH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HFQ0203138.1"
                     /translation="MFERSPSELTERENYKLLIGSVIPRPVAVVTTKSAKDIVNIAPF
                     SYFNIVSSNRPILSLAIQRKQDAVKDTAKNILETREAVIHILDEDNVEEVNKTAANLP
                     NEESELYLTDLTLTDSVIISVPALTEAKVRFETSLYEHVEIRNKNKVTADLFLLEVQK
                     YHLNETVYDDKTGRIDPRKLNAVSRLAGNDYAAIGEIFTIARPE"
     gene            5644..5850
                     /locus_tag="ACG8LA_000820"
     CDS             5644..5850
                     /locus_tag="ACG8LA_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0203139.1"
                     /translation="MLKISYKPSTDSKEMKKEYETVNDFLQGQYLEVPPLQDHFVVTT
                     VTLDGKEIEMPDQTISGLFNYFNK"
     regulatory      6075..6241
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00380"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="The M-box (ykoK) riboswitch appears to function as
                     a genetic 'off' switch that is important for maintaining
                     magnesium homeostasis in bacteria; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="magnesium"
                     /db_xref="RFAM:RF00380"
     gene            6389..6946
                     /locus_tag="ACG8LA_000821"
                     /pseudo
     CDS             6389..6946
                     /locus_tag="ACG8LA_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303250.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_process: GO:0070726 - cell wall assembly [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
     gene            7004..9043
                     /locus_tag="ACG8LA_000822"
     CDS             7004..9043
                     /locus_tag="ACG8LA_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="HFQ0203140.1"
                     /translation="MKRSDKHGKNRTGAYIAGAVILIAAAGGGYFYYQHYQETQAVEA
                     GEKTVEQFVQALNKGDYNKAAEMTSKKAANKSALSEKEILDKYQNIYGAADVKGLQIS
                     NLKVDKKDDSTYSFSYKAKMNTSLGELKDLSYKGTLDRNDGQTTINWQPNLVFPEMEG
                     NDKVSLTTQEAARGNIIDRNGEPLATTGKLKQLGVVPSKLGDGGEKTANIKAIASSFD
                     LTEDAINQAISQSWVQPDYFVPLKIIDGATPELPAGATIQEVDGRYYPLGEAAAQLIG
                     YVGDITAEDIDKNPELSSNGKIGRSGLEMAFDKDLRGTTGGKLSITDADGVEKKVLIE
                     HEVQNGKDIKLTIDAKAQKIAFDSLGGKAASTVATTPKTGDLLALASSPSYDPNKMTN
                     GISQEDYKAYEENPEHPFISRFATGYAPGSTFKMITAAIGLDNGTIDPNEVLTINGLK
                     WQKDSSWGSFKTTRVSSDVSQVDLKTALIYSDNIYAAQETLKMGEKKFRTGLDKFIFG
                     EDLDLPISMNPAQISNEDSFNSDILLADTGYGQGELLITPIQQAAMYSVFTNNGTLVY
                     PKLIADKETKDKKNVISETAVQTIVPDLREVVQDVNGSAHSLSALGIPLAAKTGTAEI
                     KEKQDVKGQENSFLFAFNLDNQGYMMVSMLENKEDDDSATKRASELLQYLNQNYQ"
     gene            complement(9152..10303)
                     /locus_tag="ACG8LA_000823"
     CDS             complement(9152..10303)
                     /locus_tag="ACG8LA_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HFQ0203141.1"
                     /translation="MEFIGILCLILISTTIGSHISRRLGIPAVIGQLLVGVLLGQAGL
                     NWVKPDILVHDFSEIGVILLMFLAGLESDLSLLKKYFRPGMFVALLGIIFPVVFGWLT
                     GKAFQVSGNEAIFFGIILAATSVSISVEVLKELNVVNTKEGSTILGASVVDDILVVLV
                     LSFSLSFLTGEASSNASLPLVLIEQLIYFVFIFLLVKWIAPFLLSFAEKVYANSSIII
                     VSLVICLGMSYVADLVGLSSVIGAFFAGIAVSQTKVKEEVYHNVEALGYAVFIPVFFV
                     SVGLEVDFSDFSEQLLFISILTLVAILTKLLGGYFGAQIAGFSQHSSLMVGAGMISRG
                     EMALIILQIGQQSQLIEPQYYSPLVIVILLSTLISPLVLKYFTKKVYEV"
     gene            complement(10457..10987)
                     /locus_tag="ACG8LA_000824"
     CDS             complement(10457..10987)
                     /locus_tag="ACG8LA_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HdeD family acid-resistance protein"
                     /protein_id="HFQ0203142.1"
                     /translation="MFETIKQNIQKYALLRAAVYIISGIAIVLNPSAVFHFIGYLITA
                     YLVLLGLLNLFEAYRFKRKTGSWSIGLFSGLFFLILALIVYAFAPAIVSILPILLGLA
                     VIINSLFQLFFSMNTKAKSWSVYSSILLLIGGFVLLFNPFKSLMLLFQIFGFILIFMG
                     IQEIINFIRIRKMTIR"
     gene            complement(11086..11436)
                     /locus_tag="ACG8LA_000825"
     CDS             complement(11086..11436)
                     /locus_tag="ACG8LA_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HFQ0203143.1"
                     /translation="MAQNRIFTTSFASVYPMYVAKAERKDRIKEEVDEIICWLTGYSQ
                     TELEYQLQKQVTFEQFFAEAPVPNPSRSLITGVVCGVRVEDIEDNLMKEIRYLDKMID
                     ELAKGKKMEKILRS"
     gene            complement(11593..13122)
                     /gene="ahpF"
                     /locus_tag="ACG8LA_000826"
     CDS             complement(11593..13122)
                     /gene="ahpF"
                     /locus_tag="ACG8LA_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008785 - alkyl hydroperoxide reductase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0000302 - response to reactive oxygen
                     species [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HFQ0203144.1"
                     /translation="MLDKETKQNLEQYLALIESPIVFSVSLDNSENSQKLAEFTKEIA
                     EMSPKISWEKRDSMRTPSFSINPVGKESGIVFAGIPLGHEFSSFLLAMLQISGRAPKI
                     SESLSLKIKKITQTLHFDSYVSLTCHNCPDVVQALNILAVLNPNITHTMIEGGMFQKE
                     IDDKKIMAVPTVFLNGEEFSSGRMTIEQIVEKITGPLIEEELFEKEPYDVLVIGGGPA
                     ASSAAIYAARKGIRTGLVADSFGGQVVETLGIENMIGTSYTEGPKLMQQVESHVRSYP
                     IDIMMNQQAVSLNKEQHFINIGLANGISLKAKTAIIATGAHWRSINVPGEKEFKNKGI
                     AYCPHCDGPLFKGKEIAVIGGGNSGVEAAIDLAGLAKHVYVLEFLPELKADQILQDKL
                     VSLANVTVIKHAATKEISGTNQVESLSYIDRRTMEMHTLAVSGVFILVGLLPNTDWLD
                     RTIEMNPRNEIVTEKNGATNIPGVFAAGDCTDSPYKQIIVSMGSGATAALGAFDYLMR
                     T"
     gene            complement(13132..13695)
                     /gene="ahpC"
                     /locus_tag="ACG8LA_000827"
     CDS             complement(13132..13695)
                     /gene="ahpC"
                     /locus_tag="ACG8LA_000827"
                     /EC_number="1.11.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0102039 - NADH-dependent peroxiredoxin
                     activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit C"
                     /protein_id="HFQ0203145.1"
                     /translation="MSLIGKKIEEFNAHAYHQGEFLEVSEKDLMGNWSILCFYPADFT
                     FVCPTELEDLQEQYSTLKSLGVEVFSCSTDTHFTHKAWHDTSDAIGKIEYVMIGDPSH
                     QISRIFDVLDEEQGLAQRGTFIIDPDGIVQAMEINADGIGRDASALIDKIRAAQYVRT
                     HPGEVCPAKWKESGETLKPSFDLVGKI"
     gene            complement(13839..14501)
                     /locus_tag="ACG8LA_000828"
     CDS             complement(13839..14501)
                     /locus_tag="ACG8LA_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFQ0203146.1"
                     /translation="MKSSLQSQAYQAIRKQIIYADLEPGRKISEKALEEHLAIGRTPI
                     REALIQLRQQELVYTIPQSGTYVSKINLVSAENARFVREQLEEQIMIECCSKLDTQTR
                     IVLETILEEQEKAVKINDERAFFRADNLFHEACFEIAGRKEVWNWLDDHNTHLERFRW
                     LRVTIQGLPWETIMEQHYDLLKALVDKKPEEARFQTGLHLHMMLKEQETVTQRYPEYF
                     QQ"
     gene            14685..16331
                     /locus_tag="ACG8LA_000829"
     CDS             14685..16331
                     /locus_tag="ACG8LA_000829"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HFQ0203147.1"
                     /translation="MIDLNNWRNFIPELSQKEVEIPHFDRASLRENGQKNPVWIHFGG
                     GNLYRGFHAEIAQRLADLGELSTGVIVCETFDEEIIERAYQDFDDLILEVVMPSSGEF
                     VKRILAATADSLYCHPDCSEHFDKMIRHFENPSLQLVTFAITEKGYRLKDTNNKYIGP
                     IAVDIKNGPKKPSHTMSILAVLLYKRFLSGAWPIALVSTDNFSQNGSQLRTSLLTIAK
                     EWQKEGYVQNTFIQYLSNEEIVAFPWTMIDRITPNPSLSVSKMLAKEGFSNMSIFQTA
                     KGNNIAPFVNTEDIHYLIMEDHFPNGRPKFEKAGVFLTDRATVDKADTMKVTTCLNPL
                     HTSLAIMGCLLGYRSIAEEMKDPDLSLLVSEIGYNEGLPVVESPGIIDPKIFLEEVIT
                     VRFSNPNIPNMPQRIATDTSQKVAIRYGETIKKYMEIEVKDPQTLVFIPLTLAAWLRY
                     LIGIDDQGKPFIPSPDPLLTDLQHKLSDIQLGTQDTSHIHEKMAPILSNKEIFGVDLY
                     QAELGRKIEEMFIKMVAGPNAVRKTLQDYLQEHGGNLSWK"
     gene            16322..17404
                     /gene="uxuA"
                     /locus_tag="ACG8LA_000830"
     CDS             16322..17404
                     /gene="uxuA"
                     /locus_tag="ACG8LA_000830"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008927 - mannonate dehydratase activity
                     [Evidence IEA];
                     GO_process: GO:0006064 - glucuronate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HFQ0203148.1"
                     /translation="MEMTFRWYGSQEEKITLDEIRQIPAVKGIVGTLMDIPVGEVWPR
                     ERIKELKEEIESRGLTLKVIESVNVHDAIKIGLPSREQYIENYKQTIRNLAEYGIEVI
                     CYNFMPVFDWVKSDLDYRLEDGSSTLAFISDDIPDDPREIVARIEHSSNEFGLPGWEP
                     ERLAPIKSLLEAYASVDEEKLRENFAYFLQSIIPTCEEVGVKMAVHPDDPPYSIFGLA
                     RIVKNREDLDWLCRIVDSPYNGITLCTGSIAEDPENDVYGILAEFCQRDRIPFAHVRN
                     IKFLANRDFYEAPHKSEYGSLDMYRILKTMYDNGFNGYIRPDHGRMIWNETGRPGYGL
                     YDRALGAVYLNGLWEAIEKGNKSKDN"
     gene            complement(17512..19065)
                     /locus_tag="ACG8LA_000831"
                     /pseudo
     CDS             complement(17512..19065)
                     /locus_tag="ACG8LA_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738699.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            19213..20354
                     /locus_tag="ACG8LA_000832"
                     /pseudo
     CDS             19213..20354
                     /locus_tag="ACG8LA_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318369.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
     gene            complement(20480..21559)
                     /locus_tag="ACG8LA_000833"
     CDS             complement(20480..21559)
                     /locus_tag="ACG8LA_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HFQ0203149.1"
                     /translation="MNNVFIFCYLEVVDLTVYQRFLANEKIRRLTVLLFVVFVLFLVR
                     SMITTILLTFIFTYLMIHLVQIIQRFVRIPTGVLAIMIYTLIVYLIYLAFTKYIPMLI
                     HQTFDMIQSVINFYEHQPKDADPVLQYIHTYIERNDFFEQLQNGASIALGYLQDIGKM
                     AVAFAMSFILSFFFMIEKKKTIVFSRLFLKSEFSWFFQDIYYFADKFVNTFGLVLEAQ
                     FVVALLNTLLTTIALAVFGFHQLLSLAIMIFILSLIPVAGVIISCIPLSFIAYSQGGI
                     RDVVYILITILIVHLIESYVLNPKLMSSKTELPIFYTFVVLLVSERFFGVWGLIVGIP
                     IFTFFLDVLKVKKIPNHLPKETDIP"
     gene            complement(21662..22102)
                     /locus_tag="ACG8LA_000834"
     CDS             complement(21662..22102)
                     /locus_tag="ACG8LA_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HFQ0203150.1"
                     /translation="MEDLYLVNQVCFPLYAASKEIIRHYTPLLKPLNLTYTQYLVMLV
                     LWEKKKTSVKELGNDLCLDSGTLTPLLKKLAEKNYINRQRETGDERIVNVTLTAQGAA
                     LQKQAEGIPQKIKSYLPLEQEELDTLQHLTRKMLDNFHQDQKKG"
     gene            complement(22159..22569)
                     /locus_tag="ACG8LA_000835"
     CDS             complement(22159..22569)
                     /locus_tag="ACG8LA_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HFQ0203151.1"
                     /translation="MKKMYSTKMINTGGRSGEVHNPDRTFELNIAAPGKRVENATNPE
                     QLFAAGFSACFNSALELIKQQKNISGASTVSAQVSLYSESETSFVLGVEIEGSIEGLS
                     LEETQELLEAAHKVCPYSKATAGNIEVTLKAVSE"
     gene            complement(22749..23183)
                     /locus_tag="ACG8LA_000836"
     CDS             complement(22749..23183)
                     /locus_tag="ACG8LA_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFQ0203152.1"
                     /translation="MHKGTEIDFVLNDSLKALELYQTIFDEIQLIEATDYPRGNNEVI
                     FTLYGTRFHMLDENTSLGLTAPTAEHPNTIWFNIIVSDIEDTHNKALRNGCVEIQEMT
                     EMMDFGVTNSMFRDPFGYLWMLHQVHREVIFEERKQLFEKYM"
     gene            complement(23283..24131)
                     /locus_tag="ACG8LA_000837"
     CDS             complement(23283..24131)
                     /locus_tag="ACG8LA_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFQ0203153.1"
                     /translation="MKETRQFIWTYIKIIFALFILGVAINMFLGPHHIAAGGVSGLGI
                     LLEAALGFDRAIVILVLNIVMLVLALLFLGKKPFFKVLFGSLVFPLIIAIVPETMITS
                     DRLLSVIFGSAIFALGVAILYKNNSSSGGTTIPPLIFKKYFHLNTSIGLFFTDAFVVS
                     LNLFIFGIEEFLYAILSIAITSIVMTYIETGINRKKSVMVMSEHYLEDIRLRLSAEIG
                     RGLTLLEAKGGYNRKSKEVLLIVVTDHEFSRMKPLIEEIDPSAFVIVSSVAEVMGRGF
                     TYHPIE"
     gene            24520..26286
                     /locus_tag="ACG8LA_000838"
     CDS             24520..26286
                     /locus_tag="ACG8LA_000838"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008271692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 13 protein"
                     /protein_id="HFQ0203154.1"
                     /translation="MDTAAIYHRPESEYAFLYTNTRFRIRLRTRKNDIKKVYVLCGDP
                     YTITTEKWYQKQRPMKKCLSTNVHDYWEIEVTSETSRLQYAFHVVGEDNTDCFYGDQG
                     IFPYRENVITEPNFYFRIPYFHQIDRFTIPEWVKETVWYQIFPERFANGDKANDPEHT
                     LPWGSKDPDREDFFGGDLQGVMDHLDYLTDLGINGIYFCPIFKATSNHKYDTIDYYEV
                     DPAFGDKKLLKNLIDEAHKRGIRIMFDAVFNHMGVHSPQWQDVLKNGEKSIYKDWFHI
                     RFFPVDSYQMTDLPETAENIPYDTFAFTPFMPKLNTANPEVQKYLLDIATYWIKEFDI
                     DGWRLDVANEVDHHFWKKFREAVTEIKPDIYILGEIWHSSQAWLQGDEFHAVMNYAFT
                     DSIKDYFAKKKITASQMVSGMNHQQMLYRDQVNEGTFNLLDSHDTARILTLCQGNKEL
                     MKSVMAFMFLQKGSPCIYYGTEIGMTGEDDPDCRKCMIWEKEEQDLELFGFIKELVSL
                     RKQLSKIISEGSTQWLIVNDREDKLYFTRKLEGQIIYVYFNQSKEPWVVEQENEVILS
                     QNCQLLEDGKAEIRQYGFLIMC"
     gene            26388..27647
                     /locus_tag="ACG8LA_000839"
     CDS             26388..27647
                     /locus_tag="ACG8LA_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HFQ0203155.1"
                     /translation="MKKRSVKQLGLGLISLGILGGLAACGNGNSSAEGEADEGKTLTV
                     SVDSGYKDYINEIKNTFEKENDVKIKLVEKDMFDQLESLALDGPAGKGPDVMMAAYDR
                     IGALGQQGHLAEVKLGNEAAYDETDKAQVTYDGKIYGEPAVIETLVLYYNKDLVDTAP
                     STFKDLENLSKDSRFAFESEAGKNTGFLAKWTDFYYSYGLIAGYGGYVFGDDGTNPSD
                     IGLNNAGAVEGISYATDWFKNVWPKGMQDIKSAGDFASQQFMSNKTAAIIDGPWQAQT
                     YKENNINYGVAKIPTLNNGQPYQPFGGGKGWVVSNYAKNKDLSQKWLDYVTNQENQEK
                     FFEMVNEIPANQQARETAKAKNDELTTAVIEQYETAQAMPNIPEMGEVWTGAENLMFD
                     AASGSKTPKESADEAVKTISEAIEQKY"
     gene            27794..29095
                     /locus_tag="ACG8LA_000840"
     CDS             27794..29095
                     /locus_tag="ACG8LA_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFQ0203156.1"
                     /translation="MQQDKTSNINEKKITLCSLIPGMGQFVNGQAFKGIVFFAIFVLF
                     IGQMLLGGFHALVGLVTLGSIPMEDHSLFILIEGTLQFIITIIFLIFYGLNLLDAYRV
                     AKMRQEGKKINRTMKEVIHNIGDEGFPYLLTLPAYLLMIFTIIFPVLVTLFTAFTNYD
                     FNHIPPASLIDWVGAKNFFSIFFLSSYRNTFFAVFSWTVIWTLCATTLQITLGILTAV
                     VAHQKFIKFKRIFGIIFLLPWAVPAFITIMSFSNIFNDSVGAINTQVIPFINQLPFVD
                     ISAISWKTDPNWTKVAIILVQGWLGFPYIYVMVTGILQSISEDLYEAAKIDGANAWQR
                     FSNITLPAVFLVAAPTFITQYTGNFNNFSMIYLFNNGGPGSVGGGAGSTDILISWIYK
                     LTTGTSPQYSMASAITLIISVIVICVSLLVFKKTNAFNMGD"
     gene            29098..29949
                     /locus_tag="ACG8LA_000841"
     CDS             29098..29949
                     /locus_tag="ACG8LA_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HFQ0203157.1"
                     /translation="MKKFHSSARFQKRLSHFFTYFFLLILSVIIIYPLLITASTAFKS
                     GNIAAFSLDLSSDWTLGNFTRLFSETLYGTWYKNTLIISVLTMIVQVTVVTLAGYTYS
                     RYRFIGRKSSLMFFLVIQMVPTMAALTAFYVMAFLLEALDKYWFLTMIYIGGGIPMNT
                     WLMKGYFDTVPIDLDESAKLDGAGHFRIFFQIVLPLVKPMLAVQALWAFMGPFGDFML
                     AKFLLRTPENQTVAVGLQTFISDVTNQRVSLFAAGAILIALPICLLFFFLQKNFVTGL
                     TSGGTKG"
     gene            29962..30777
                     /locus_tag="ACG8LA_000842"
     CDS             29962..30777
                     /locus_tag="ACG8LA_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrose utilization protein MalA"
                     /protein_id="HFQ0203158.1"
                     /translation="MQTFPLNYFSALRTPTQVFAGRKLLSWPKFFLIFVFLVSLMVMP
                     VTLFYANQIQAIPLEQFLSVHSLIDEQGTQKFSELELSETGLQASQQTIAVTPEILVG
                     VSLSEKQQSDHGTFIDFEKEQWVIQQKDKSGIRRYTMNYSPSFQPDSVRTPEDFQRFL
                     EREFYASNRPTIILSYSLSLGLVLFVMTSLILFGASFFLWMTRKSQLSSIHTFKESAN
                     LMLNVMGIGSMAAAVVGFIHFDFILMLSVQTTITVLLLLWVFVKTRFKDKRVE"
     gene            30928..32094
                     /locus_tag="ACG8LA_000843"
     CDS             30928..32094
                     /locus_tag="ACG8LA_000843"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFQ0203159.1"
                     /translation="MLEKTLYNQLFSRSFSLPVEVNYWDGTTKQYGDTDTPPQIKINI
                     HEEIPMKEITSNASLALGEAYMDHRIEIEGSIQALINDAYQQANSFLRGKDYLKWLPK
                     KEKHTKQKNKEDIHAHYDLGNDFYKLWLDPTLTYSCAYFNTPEDTLEQAQINKVHHIL
                     DKLFIKEGETLLDIGCGWGTLMFTATKEYNVKATGITLSEEQYDLITKRIKEEHLEDK
                     CRVLLMDYRELKGETFDHITSVGMFEHVGSENLEGYFKVVKDLLKPKGTALIHGISRQ
                     QGGATNAWINKYIFPGGYVPGVTELVDNITKNDLQLIDLESLRRDYQLTLEHWTKNFH
                     QVQDQVTKEMGDSFYRMWDLYLQACAASFESSNIDVIQYLLVQPGNNDIPMHRA"
     gene            32324..32971
                     /locus_tag="ACG8LA_000844"
     CDS             32324..32971
                     /locus_tag="ACG8LA_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HFQ0203160.1"
                     /translation="MKKTVIYTSLFAALFLAACQSNTNQGTSGNTSSSSEQRSSQVSD
                     SSTKASTSSSSQTKSSSEASTQSDIKVSAARAIELFQDKYPDTAITSLELDSDWGSYF
                     YKIEGVDDQKEYEARIDAQNEKMETENPETLDRDEQNGQKKKEDGLDVDKLITIEEAA
                     KIAVDKVGSGTATDWDLDKDLGTTYWEVKVKDGNQSTSVKINSQTGEVLSTEQDD"
     gene            33055..33999
                     /locus_tag="ACG8LA_000845"
     CDS             33055..33999
                     /locus_tag="ACG8LA_000845"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004152 - dihydroorotate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HFQ0203161.1"
                     /translation="MSLETTFANHIFANPLMNASGVHCMTTQELDELAHSEAGAFITK
                     SCTINERKGNPEPRYFDVPLGSINSMGLPNLGFSYYLEYALAYEKVQENQNQPLFFSI
                     AGMSVQENLEMLEKIEKSGFNGITELNLSCPNVPGKPQLAYDFEATYETLKEVFSIFS
                     KPLGIKLPPYFDFAHFDQMADILNQFPLTYVNAINSVGNGLYIDTEQEAVVIKPKEGF
                     GGIGGEYIKPTALANVRAFYTRLKPEIQIIGTGGIRTGQDAFEHLLCGASMLQIGTEL
                     HKEGPEIFSRIIKELTQIMSEKGYTSIDEFKGKLRTIS"
     gene            34134..35585
                     /locus_tag="ACG8LA_000846"
     CDS             34134..35585
                     /locus_tag="ACG8LA_000846"
                     /EC_number="3.5.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase"
                     /protein_id="HFQ0203162.1"
                     /translation="MNDATELAKELKEKEFSFQELVTDIQKKIKKQNHELNAFVALEP
                     FESNSHELLIPQSEKGPLAGIPFPLKMLGQEKKGWLATSGSRLFETHRASHTSNYVRQ
                     AEAIGLVPFGQTNAPEFGFKNITDPVIYGPARNPWNLECTPGGSSGGAAAAVSSGIVP
                     LAGASDGGGSIRIPASFCGLIGLKPSRGTMPVGPYAWRGWQGAAIDFGLTVSMRDTEA
                     LFYGMRSIHSGAPYQVSPVEWQTHPRKKRLKIAFCVDSPIHSQISEEAVLAVKKAVDF
                     LGKEGHDLTEIPYPLDGRKLITSYYQMNGAETAAMIRSIETGIQRAVRKEELEPISWT
                     LFQYGQKLSAATYIDSLHVWDEAAIVMENLHQEYDLFLSPTTAFTAPKISEDLQSDAI
                     RAQMEHISDCSEVEGLDVVSSMFEESLKITPYTQLANLTGQPAISLPTHLTKENMPLG
                     IQFMAARGREDLLFQIGYLFEANHQFHLPNPWK"
     gene            35606..36442
                     /locus_tag="ACG8LA_000847"
     CDS             35606..36442
                     /locus_tag="ACG8LA_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HFQ0203163.1"
                     /translation="MKKKRLFALITSAFFILSACGTAAANQEDNSWSNVEKKKELVVA
                     TSGTLFPASYYNDQNELVGYDVDLAKEVAKRLNVKISFKEYNVDGQITSVSKRESDFA
                     ANDFGITKEREKKFSLSETFKYSFDSMIVRKKDDSGIHSLEDLKGKKAAGEPNTSYMR
                     LAEKHGAKLVTYDNATNDQYLSDVANGRTDVILNDYYLQKMAVSALPDIPVKILENVY
                     FNENESGFLLKEGNDALKKKIDGVLKEMKEDGTTKKISEKYFQTDVSVKPKETMAESV
                     SE"
     gene            36442..37101
                     /locus_tag="ACG8LA_000848"
     CDS             36442..37101
                     /locus_tag="ACG8LA_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HFQ0203164.1"
                     /translation="MYFPLIDFSLMWTSLPFVLQGLVYTLGIGFVSFLLGNLVGLLLT
                     VLGLLDWLPLNVFIRFYLSFFRGIPALVLLFLLYFGLPYQLSALTASVICFTITSSAF
                     IGEIYRGSLAGVSSGQWDAGLASGFSFFGVLKYIVLPQAFRISVPALSNVAMDLVKGT
                     SLAATITVPEIFQKAKIIGGRTFDYFSLYILVALIYWVICIGIEKVQQYLEKRSMHQS
                     I"
     gene            37227..37916
                     /locus_tag="ACG8LA_000849"
     CDS             37227..37916
                     /locus_tag="ACG8LA_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0203165.1"
                     /translation="MKTPLTIEIESSLYQYCIEQGGLVVEEVTMPDDQGIVDTLSCLT
                     KFDGSREWRCYELKVTKADFRSTAKLSFVGHYNYFVLPSKLYEEVKTEIPTGIGVLVY
                     RPYTVEEEMPASGTFLIAKKAAKKELAVPEEALTNRFMASLFREVRKAKQMERGVKYF
                     PTDQLYKELKRRSENQDPFSNERYYERFLEEIASQAINELQEEVIALQHDYEYLRQQQ
                     QIRRLPTEPLE"
     gene            37922..38878
                     /locus_tag="ACG8LA_000850"
     CDS             37922..38878
                     /locus_tag="ACG8LA_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sce7725 family protein"
                     /protein_id="HFQ0203166.1"
                     /translation="MYYPYLRGKQFDLLALKEALSRGLLSNKIQPVIEPVRDSATLKN
                     VIELFQKKHHPIAVIQNPQVGQFKLFDQHVHSWTVKENSSVVPAQILTPENLSEVLDS
                     PPAFLVFDGQHYPKDTEVWKQLAGVDSKFLIPDTSRFRIWLPENKIVIRDSFQTRKHV
                     ESYADKTDDFFSDDYLFFHADGYIGFSDFTIEGSRYFDKGFPSRALAIHLTYIDAYGN
                     IRVKHFVSDSNDSAKDQALKFLEAGDKMKKWIMRHHHQLLITSGMIELLALYQQQKFP
                     GLGVLKKWSLMHHLELISHLLDHPKDWLKYYSKVQELYEVIQ"
     gene            38922..39434
                     /locus_tag="ACG8LA_000851"
     CDS             38922..39434
                     /locus_tag="ACG8LA_000851"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFQ0203167.1"
                     /translation="MYIRQTRKEEVEEVVEIINAAADFIASQGSPQWQNGQKPTKETI
                     LNDIERKESYVLIVEDQIAGTAALVSSVDPVYTKIDGSWKESTGPYLSIHRVALAEST
                     RGKKLAKPFLEHLLTIAASKNIQDIRIDTYPANEPMEKTIYSAGFTYQGMIEFPFEHG
                     ERKAYQIIIN"
     gene            complement(39690..40238)
                     /locus_tag="ACG8LA_000852"
     CDS             complement(39690..40238)
                     /locus_tag="ACG8LA_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HFQ0203168.1"
                     /translation="MNYCYVFIGPSGSGKTSLAEAIFQPEQKIITYTNRSPRPGEKDQ
                     EDYYFVSDNTFNQMIKGNEFAEWDQYAQHKYGSSKAEIKKKLTVGNCYAVLTANGFWH
                     LYEYFGTVVRPIFITISKETLQSRLKKRGDSSEQISARLAVYVEDLAQLKRLKAIPSL
                     LVVSNDGAFQEAADKIKKGLLI"
     gene            complement(40327..41508)
                     /locus_tag="ACG8LA_000853"
     CDS             complement(40327..41508)
                     /locus_tag="ACG8LA_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside transporter C-terminal
                     domain-containing protein"
                     /protein_id="HFQ0203169.1"
                     /translation="MSYLLGIIGLFVTLGLAFLISSNKKAIKLKPLIVMFVLQLVLGF
                     VLLRTTFGTAVVSVLAKMFDHLLAFAGQGVDFVFAGVANKGSAPFFLSVLMPIVFISA
                     IIGILRYIKILPLFMKAVGLGLSKINGMGKLESYNGVASAILGQSEVFISIKKELPFL
                     SEKRLFTMSVSAMSTVSMSIVGSYMALIDSKYVITALVLNLFGGYILASIVNPYVLEE
                     KEDELIIEENKEQTFFQMLGEYILDGFHVAITVAAMLIGFVALIAMINAIFHGIFGIT
                     FQEILGYIFAPLAFISGIPWKEAVDAGSIMATKLVTNEFVAMTELANGNFHFTERTTA
                     IISVFLVSFANFSSIGIISGAMKGLNEEKGNLVAKHGLKILLTATLVSFLSAIVTGLL
                     V"
     gene            complement(41744..43252)
                     /locus_tag="ACG8LA_000854"
     CDS             complement(41744..43252)
                     /locus_tag="ACG8LA_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HFQ0203170.1"
                     /translation="MKKIGFDSEKYIEEQSAYILERVNHYDKLYLEFGGKLVDDKHAK
                     RVLPGFEEDAKIKLLQKLKDQAEILICVYAGDIERNKIRGDYGITYDMDILRLIDELR
                     GYGLLINSVVITRYSGQPATKVFINKLERRNIKVYKHSEIEDYPVNVEKIVSEDGFGK
                     NEYIETTKPIVVVTAPGPGSGKLATSLNQLYHESQKGHAAGYSKFETFPVWNVPLKHP
                     LNIAYEAATVDLKDVNMIDSFHFDAYNKVAVNYNRDVETFPVIKRIIEKITGKESVYQ
                     SPTDMGVNRVGFGIVDDTVVQEASKQEIIRRYFQTECDFKKGLIDEEAVNRIKLIMEE
                     VGLRPEDRNVVVPAHDYADKIQAQSPTKDPSAVIAIELPDEVIITGRTSSLMDASAAV
                     ILNAVKHLAHIADDIPLLSPLVLETIQGLKSKTLHSSLDALSINEVLIALSISAVTNP
                     IAQVAYDKLAELEGAQAHSTVMVNKNDEQTLKKLGIDITCAPVYPSENLYYQ"
     gene            43411..43602
                     /locus_tag="ACG8LA_000855"
     CDS             43411..43602
                     /locus_tag="ACG8LA_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0203171.1"
                     /translation="MKKRQKKKNAYKHYIRSIFTGYERMLEDPELEQLTFTYLNEETQ
                     LTRDEHQRIHFTTRDLPSK"
     gene            43805..44722
                     /locus_tag="ACG8LA_000856"
     CDS             43805..44722
                     /locus_tag="ACG8LA_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="coiled-coil domain-containing protein"
                     /protein_id="HFQ0203172.1"
                     /translation="MKEPDTNANYEPDELEETNADQDTGQESSSFYDIKEKASMNLSQ
                     LLEDLQAFEKAVREEDIPEIYRLYNGRLNEELKRSSNENHEIDQLLMRKIHDRFLQEF
                     PFMEQVENISPTMSYYKIGTYYHDRPTVGIDASLPEIFVLPKIDEEWEKYSQPESTDY
                     DKKINELDAKVITAQTEIERLDEQIKEINRQMTDLNDNKGFLNRKKIEEEIQELEKKK
                     QVLSNEKLGWLPYIETPETIQQQKEALKQEARADQLRAAIVEKEQRQIRRYFGSKEGF
                     GQAIHEFLMNYLGNENPNNQSNEGGSEYE"
     gene            44715..45788
                     /locus_tag="ACG8LA_000857"
     CDS             44715..45788
                     /locus_tag="ACG8LA_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0203173.1"
                     /translation="MNEHDEAEWTKNEEQTEDHEETNTSLEEQTSNPLDDTEEIPMLE
                     ETKIHEKEKVTPTNTNTAENTHAYEITENPGYLEGKEQDHQDIVSLIETAEAELADLR
                     MRKDLIESDFPQLLESYDRFILNEEPISTIGKTSLIEYFTYELLKPLNDIGLERSNSA
                     YDTWKTRHFSINYTLNGQNELVFSFVLPTIDQRYQVESMSLLNVSPETMEINVQDDRV
                     LSLIRHWSVDRVFSAGQITIFNHKLNQLLAHARTLGFTVNQTLLDNTKPLRLNLQSEF
                     ELTNEVLDDIFIVAMKNPSYDMEKINETTYQVRLDKGQSLTITTNEKDQTVLSISSGD
                     YPRSVIDFFINYEFLVPLMVRKS"
     gene            45936..46454
                     /locus_tag="ACG8LA_000858"
     CDS             45936..46454
                     /locus_tag="ACG8LA_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0203174.1"
                     /translation="MSTNKIAQLSLLSAACVAGRIAFQFIPNFQPMTAIFLFIVLYLS
                     LKDALIVMSLSIAISSFYFGVGPWVIGQWISYTVVLSLFSIVCLRKTVQRNLWLKGVC
                     FFLAGMVYGIGMTVFDTLLYRLPQPWIYYLQGVSFDLMHSIGNVVFFLVFLPVVKRFY
                     NHSGGKNEKNNL"
     gene            46435..46827
                     /locus_tag="ACG8LA_000859"
     CDS             46435..46827
                     /locus_tag="ACG8LA_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4430 domain-containing protein"
                     /protein_id="HFQ0203175.1"
                     /translation="MKKIIYSLLAMSVSILILTSCSTTYTQSASNQKEEVKTSQKATI
                     TLQENGQNFSEKEVFFKKGDDLLSILKRNFEVKEDNGFITSLEGHSQDEKNQLYWMFT
                     VDGKSATTGAKEIKLNDGQSVIFNLSKL"
     gene            46903..47838
                     /locus_tag="ACG8LA_000860"
     CDS             46903..47838
                     /locus_tag="ACG8LA_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HFQ0203176.1"
                     /translation="MENFKKSGMFSVIAALGANILVAISKFVGYAISGSAAMLNESIH
                     SIVDCSNQILLLFGDKQANKGQSELHQFGEGRAKYFFSTIVAMMLFFGGGALGVMEAF
                     EKLTHPSHEVGNPIIVIAILLFGLVIEGSSLRVAMKEIKELNTEKLSTMRFLRESRHS
                     EILIIFTEDLCAVIGLVLALAGTILTYATGIAAFDAISGLLIGFLLMGAAIFLAKEFY
                     SLIIGESVTASDLSKIKLAFERPEISRLIDIKTVHLSPTEILVAAKADIVGNKENEAY
                     SVINDIEKNMRQSLPDKKMYIYIETDKYDPNYSRK"
     gene            47971..48750
                     /locus_tag="ACG8LA_000861"
     CDS             47971..48750
                     /locus_tag="ACG8LA_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HFQ0203177.1"
                     /translation="MNKKKSAPWLQALHAVMPLCISYIPVGLACGVLLQKVGFDPLLS
                     GLLSILVFSGGAQFLVASMLTTQASFATTLLMVFFLELRYTLLGASLAGFMKKEKRTF
                     LAVFSQSLNDENYAVNYLKFSTDPSWNKRKALYVNWFSMTAWAGNNMIGNFFGSVIRV
                     DADLVHFALTAMFIFMFIMQMKSALLIFTGLFSGVLGVVFMVLFQNTFGLIAATVIAS
                     FAGFMLEKAFKKEKAKKLRDRGKDVNEPLFNFPEQEANHHD"
     gene            48743..49060
                     /locus_tag="ACG8LA_000862"
     CDS             48743..49060
                     /locus_tag="ACG8LA_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HFQ0203178.1"
                     /translation="MTKLYLLLLVACLFIVAYIPRLFPMLYFTHRKVPSWFSDWMKYV
                     PVALFAALAFKDVFITHEHLDIAWNIKIAAMILVAGVAYKTRSMALSVLTGLASVFLL
                     SML"
     gene            49304..50914
                     /locus_tag="ACG8LA_000863"
     CDS             49304..50914
                     /locus_tag="ACG8LA_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HFQ0203179.1"
                     /translation="MNKKLMQGTFWLTFANLLCKVLGVVYLIPWLSMMGNNQDGMLAT
                     TLYNVGYLPYGLFLMLGTVGFPNAIAKKVAVATKEGDNAACRLIFRSTINIMFVIGIA
                     SAALMYLFAPLLAGISPIANVNNGILAIRSLCPSLIAIPILSAMRGYFQGKNDLRPYG
                     TSLIIEQAVRVIVILAGTYYLRVLTDGTILEAVLISTVASFFGGLAAIIHMYIVGRRK
                     DFFELKDFLISSRYFERENRSASVSIIRETLPFIFVGSVITIVQMIDQVTMKPLLHFF
                     RPEIADQQLEFLFSRASVNPNKLTLILISMVGTVAISSLPILSTMKKKDRIQIEKTVG
                     DSFSIALLILLPSLTGMSLLAGPLYTLFFGYDPESVGYFQMALLASLFFSLFTILSTM
                     LQSLNHHRFAIRLTVEAIILKVIFQVIGLGLVGGYGMSLSNGLAFGIVFVRGYHFMCK
                     EYRIAPLAKISNFFLKTFRSTLIMLAVCFAVFFLLNQRLSMESKSYAMIYCVAVGSIG
                     GLVFLFSQFGKNGFRMLKNVKHHSRSKE"
     gene            51071..51919
                     /locus_tag="ACG8LA_000864"
     CDS             51071..51919
                     /locus_tag="ACG8LA_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005504 - fatty acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HFQ0203180.1"
                     /translation="MKLAVVTDSSAYLPERIKNHPDLFVIPIPLIMDGKIYNEGIDIE
                     ADEYYGLLKNSKDFPTTSQPVVGEVLGLYEELKEKGYDTILSIHLSSGISGFVNTLFA
                     MKDDISGVTVIPYDSKITSMPMGHMVEAALDLNDEGQSLDEILAHIDRIRDNTYAYLI
                     VDDLNNLVRGGRLTNGAALIGSLLKIKPILTFSEGKIVLFEKIRSSKKAFARAEEIIG
                     RRNNEIQPPVKLYVIHANNLEVAIAEKEKLQKKYPNAEIEIGHFGPVIGTHLGEKAIG
                     IAISAQ"
BASE COUNT        17394 a         9206 c        10043 g        15308 t
ORIGIN      
        1 ggcttttcta aataaaaagg aaacaaaaat acgatttaca gatatgatta aataaaatca
       61 taagaaaaac tggaggcgtg tatcaggaat gctggaaaat tacatcgagc gaaatatatt
      121 tagaaaagtg tatctgtgtg aacaattatt tgaattccaa gaaatagaca tcgaacaaac
      181 agctatttct ctaagggtga ctacaccaac gatccttcac gatctagaaa gtctagccga
      241 gtgtctagaa tattgtataa aagaacaagt aagagagaag cataagtata aactcgtatt
      301 caaacatggt attgctcttt ctgagctcac acagtttctg tacggtcaat cttatttttt
      361 aaagttttta agttattatt ttaatggtat attcacgagt acagaactgg ctgatcttga
      421 atttatttct ttgagcaaag tatatacaat caaaaaaatc gtattggatt tttttaaaga
      481 aaatgattat ttgaaaaata aagaaatcat tatcccagaa tttgactcgc ggaacatctt
      541 gctagcttta gtacgttatg tcaattggga aggctatgaa aataaaaatc cgtatgtaga
      601 agaagcttgt aacgagttga ttgattatgt agagactcat ttttttaaaa gaagatattc
      661 ggaagatgaa aagtccttta tcatacgagg aatagagatc gcaatcggaa gaaaggcatt
      721 tccccttgga ctgaaagaag aagataagaa aagcgcagaa acgaagccgt tatttcaatt
      781 agtctgtcaa ggattggaag agcaaaaagg aattctagac ttacaagaag aagatgtcta
      841 ttatattttt tctttgttca acagtagaaa ttataccaat gagaacatgg agctgttaag
      901 aaaagatttc gaagttgttt ataaaaattt tgttctcaat gacctatcac tgaatgaatt
      961 gattttacag attattagta tcgctgaaat cgacgatgca gaaaatttta ttttcaagca
     1021 atccttttta caatttgtcc gtacgttgtg ggcagatgga caagtatttt taccggaaag
     1081 gatctatctt ctatcagaaa aagaacaact tctgtacgga aaaattgtag aaatattgga
     1141 agagtggaaa aagaaaaatc aaatccaact aagatggaat gaaaatttca ttcgaaaatt
     1201 cgtcaaaagt ctttctttga tcaacagtga acaagcgggg agacaggaaa tagaaatttt
     1261 tgttgtttca gaaagttcag tcaaacaatt tttttatcga acccaatttc atttgtatgc
     1321 ggaagaaggc atcgctgaaa taaatcctat tttatttcgt tcattagaag aattgcctga
     1381 tgaatgtcta tgtgcgaaaa aaagagtggt tttgtgcgat gctgctagct atcaaaatgg
     1441 attagaaact gaaaagacaa agatctatcc aatctcatta aaaggtgcaa acatccattt
     1501 gtatcatatt gctcaggaac ttcacctatt aaaaaaacat atttcttgat gagaccttaa
     1561 ttaggagacc ttctacaaag ctttttaatt gtctgtagaa ggtttttatt tgagtcctga
     1621 ttcgtgcgaa gatctactta tataacaagc tttctctgaa atttttttaa aatgctattg
     1681 acttagagtc aactctaagt agtagaatag ataaagtgta acaaatctat tttcattaaa
     1741 agaagatagt acggaggaga gaatgtatta tgagtacagt attacatgta ttggatgcaa
     1801 tcaatagccc cgcagatgtc aaaaaattat ctgttgagga aatgaaacag ttggcagaag
     1861 agatgcgcca aaaaatcttg caaaaggaca gcgatgtagg tgggcacgtt ggtccgaatc
     1921 taggtgtagt agaattaacg attgcgtttc attatgtatt tgattcacca aaggataaaa
     1981 tcgtttggga tgtttcccat cagtcttatg gtcataagct tttaactggt cgaaaaaatg
     2041 gttttgaaaa aggacattac cgtgaagtga gcggatattc caaccaacat gaaagtaaac
     2101 atgactattt tacagtgggg cacacatcta catctatcag cttagcaaca ggtttagcta
     2161 aagcgagaga tctgaagaaa gaatcaggaa atgtggtagc atttatcggt gacggctccc
     2221 taagtggtgg cttagctttt gaaggattga acaatggtgg tgttttacaa tccaatctaa
     2281 tcgtattagt aaacgataat gagatgtcta ttgatgagaa tcatggcagt ttatataaaa
     2341 acttagctga gcttcgtcaa accaacggta aaagcagcaa taacctattt aaagcaatgg
     2401 gatttgatta tcgttacgtg gataatggaa acgatctgga aacggtgatc cgtttatttg
     2461 aagaagtaaa agatattgat catccgattg tacttcacgt ccatacggaa aaaggtcgcg
     2521 gttatcagcc ggcaatcgat aataaaatga aatatcattg gcatgtacca tttgatctgt
     2581 ccaccgggga ggcaaagcaa gtaacttctg gagaaacatt taatatgatc atcatggatt
     2641 atttggataa gaaaatgcaa acaagtacag ctcctattgc cgcagtcaat gcagcgatac
     2701 caggcgcctt tggactgaaa acattccaag aaaaacatcc agatcattat tttgacgtgg
     2761 ggatcgctga acagcactct atcactttcg cttctgcttt ggcttctcag ggagtacgtc
     2821 cagtcgtctt ccaatcaagt actttcttgc aacgggcata tgatcaatta tcacatgatt
     2881 tagcgatcaa cgagaatcca gtgattattt tagtcggtgg cggaacgatc tcagctagtg
     2941 accgaacaca ccaaggaaca tttgacattc cttacttatc aagtatcccg aacatcaaat
     3001 atcttgctcc agcaacaaaa gaggatatga tctctatgct agattgggcg ttcgaacaaa
     3061 cagcgcagcc tgtagcaatc cgaattccta cacatggtgt agaacatggt acagctatcg
     3121 caaatgatta tagtattcca gcctatcaaa cagtaaataa tggaggaaaa gtagcaattt
     3181 tagctttagg cggttttctt gaattaggaa aagaaacagt aaaagctttt agaaaaaaag
     3241 gaatcgaagc aacgttgatc aatccaggaa cgatcacaga aaatgacgta gaaacattag
     3301 ataaattaaa agaaacacac gaattagtca tcacattaga agatggtagt ttgtcaggag
     3361 gatttggcga aaatatcagt cgttattatg gtgattcttc aatgaacgta ttaaattttg
     3421 gtgcagagaa agaattcacg gatagcgttc ctgtagggca gctttatgaa cgttatcatt
     3481 taacaccaaa acaaatcgtt gaagatagtc tgcgtgtctt gaatattcaa taattcatta
     3541 tgctcaccat ccagataatt gtttatacta gtatctggat ggttttttca ttataaaaag
     3601 caaaggggtg gatgttatgt atcagcaagt agaagaatat gtcaaaaagt tccaagaaaa
     3661 atatcctagt tatcaatcag aaaaattagg tttcttttca tttggggata cagaaaaaat
     3721 ggcagacgag ttgagcgaac tagttgtaaa aaagataaag actggtacat caagtggtta
     3781 cgatctgtat aaacaagaga atgagccttt accaaaagtt ggtcaattag acgtggtcct
     3841 gaatggaaaa aatgaaccag tttgtatcat caaaaatata aatgtgacca tcttgccttt
     3901 tagtgaagtc acgaaagagc atgcttggaa agaaggagaa ggggatcgga cattagctta
     3961 ttggcggaaa gtccatgctg agttttttaa acatgcttat aaagaagcgt tgaacataga
     4021 atttacagaa gagaagctgg tcgtatacga agaatttgaa gtaattttct tttagtaaga
     4081 aaggtctgct gaaagaaata gctcattatt gtctcctgaa tagaaaaggg ttacattttt
     4141 atatgaagct gtatttttat ataacattac tggaggagat attgtggata cactggaaca
     4201 aatcaaaggc ggagtcgtcg tttcttgtca agctttggaa aacgagccgc tacacagttc
     4261 ttttattatg gggagaatgg ctttggctgc aaaagaaggc ggagcagttg gtattcgagc
     4321 aaatacgaca gaagatatca atgaaatcaa gcgaatcgtt gatttaccgg taatagggat
     4381 tatcaaaaga gattacgatg ggtcagaagt gtttattact gcgacagaaa aagaagtgga
     4441 agaacttttg gagacgcaag cagaaatcat tgcactggat gcaacttctc gtaaacgtcc
     4501 gacagaaaaa acaactgctg aacttgtcca aatgattcac gaacacggtc ggttagctat
     4561 ggcagatatt tcgacttttg aggaagcgct tcaagcgcaa gaagatggtt ttgatctttt
     4621 gtctacgact ttagcaggct atacagaata ttcacgaaag acgcagacac ctgattttga
     4681 tttattgaat caaatcatag aacaagtcga tatcccagta attatggaag gacatactga
     4741 ctctcctgaa caagtagaga aagcatatga attaggtgct ttttcagtcg tagttggatc
     4801 tattatcacc cgtccgcaat tgatcactaa aagatatgtc gaagccgcaa gtaaagcaaa
     4861 taactaaaaa acacgcacgg cacagattct tgacaaaaaa gaaaaattga tagatagttt
     4921 aaagcagatt ctaagaagat gaaaaaagca ttacttttca ttttgtcttc aagatctgct
     4981 ttttaacgaa ttttatagaa agaaggcgaa accatgtttg aacggagtcc ttcagaattg
     5041 acagaacgtg aaaattacaa gttgctgatt ggttcagtca tccctagacc agtagcagta
     5101 gtaacgacta aatcagcaaa agatatagtg aatatcgcac ccttcagtta cttcaatatc
     5161 gtcagttcga atcgacccat cttatccttg gcgatccaga gaaaacaaga tgcagtaaaa
     5221 gacacagcaa agaatattct tgagacaaga gaagctgtta tccatatcct tgatgaggac
     5281 aacgtagaag aagtaaataa aacagcagcc aatctgccta atgaggaaag cgaactgtac
     5341 ctgactgact tgactttaac tgattcagta atcatttcag taccagcatt gacagaagca
     5401 aaagttcgtt ttgaaacatc cttatatgaa catgtcgaga tacggaataa aaataaagta
     5461 acagctgatt tatttttgct agaagtacag aaatatcatt taaatgaaac agtctatgat
     5521 gataagacag gaaggatcga tccaagaaaa ttgaatgctg taagccgttt ggcaggaaat
     5581 gattatgcag caataggaga aattttcacg attgcacgtc ccgaataaaa aggagcacta
     5641 gttatgttaa aaataagcta taaaccatcg acagattcaa aagaaatgaa aaaagaatat
     5701 gaaacagtga atgattttct gcaagggcag tacttagaag ttccgccatt gcaagaccat
     5761 tttgtcgtta ctactgttac tttagatggt aaggaaatag aaatgccaga tcaaacgatt
     5821 agcggattgt ttaattactt taacaaataa atatttattc cgaaaagtga aaaaacatat
     5881 aaaaaaacac ataaaactaa aaaattatca aagaatcctg gtgcaactga aagaatttgc
     5941 aacgggattc tttcaactta tttgttattt ttttctaaaa aatattaaag attgttaaat
     6001 ttcactattt catttcaaat tccattgcct aatcattagg aaaagtctat catgaactcg
     6061 taaatagaat atagtaataa ccttgttagg tgaggctcct atacaaacat aggctgttgc
     6121 ccagaaacgt cgaaagtcgc caatgggtaa aacagaaact gttggattaa ggctttttcc
     6181 aatagctaag aatgttttct ttacgttgta tagtgctaaa actcggacga tgagatgatg
     6241 ctaggtcaga attcttgttc gaaaaggttt ctgacctttt ctttatattt ttgtgactga
     6301 cttatttgat gagacaaact cgctcctcac ctgacaagtg gattgctgtg tgaggaggag
     6361 atgcggtgaa aaaagatcga ttggtggagg tcgctcggat tcacttctgg ttgcacaata
     6421 caaccagaaa acacaacaag caaaactgat ctctatcatg agagattcat atgtcgatat
     6481 tccaggttac ggaatgaata agataaatgc agcttactct tatgggggag ttgatttatt
     6541 aaatcaaaca ttaaaggaaa atttcaaatt tgaagctccc tattatgcaa gtatcacatt
     6601 tcaagatttt atcgattgcg ttaatgaact gtttcctggt ggagtcaaga tcgatgcaga
     6661 aaaatctcta gatttagatg gcgtatatat aaacaaagga gagcaagtga tggatggtaa
     6721 tactttactc cagtatgctc gatttcggga agacaaagaa ggagacttcg ggaggatcag
     6781 aaggcagcag caagtgatca aagctatctc tcagcagctg aaagacgtaa cttcaatatt
     6841 caagctaccc aaagcggttg ggaaattact tggtagtatc caaacgaacc ttccagaaag
     6901 tgtgcttctg gattgtggta tggatttcct caaagacata tgttagaata aacaggtata
     6961 aatagtgaaa taaaggaatg acaagcaaga gaaggaggaa aaaatgaaaa gaagtgacaa
     7021 gcacggcaaa aatcgaacag gcgcttatat tgccggcgca gtgatcttaa tagcagctgc
     7081 gggtggcggt tatttttact accagcacta tcaagaaacc caagcagtag aagctggaga
     7141 aaagacagtt gagcaatttg tccaagcttt gaacaaggga gattataaca aagctgcaga
     7201 aatgacatca aaaaaggcgg caaataaaag tgcattatct gaaaaagaga tcttagataa
     7261 ataccagaat atatacggtg ctgctgatgt caaaggactt cagatatcga atctaaaagt
     7321 agataaaaaa gacgattcta cttacagttt ttcatataaa gcaaagatga atacctcatt
     7381 aggtgaattg aaagatcttt cttataaagg aacattagac agaaatgatg gtcaaaccac
     7441 gatcaactgg caacccaact tggtttttcc agaaatggaa ggaaatgaca aagtaagcct
     7501 gaccacacaa gaagcagcaa gagggaatat tatagatcga aatggtgaac cattagcaac
     7561 aacaggcaaa ctaaaacaat taggagtcgt tccaagtaaa cttggagatg gaggcgaaaa
     7621 aacagccaat atcaaagcga ttgcttcctc cttcgactta acagaagatg ctatcaatca
     7681 ggcgatttca caaagctggg tacaacccga ttactttgtc ccattgaaaa tcattgatgg
     7741 agcaacgcca gaacttccag ctggagctac cattcaagaa gtagacggca gatattatcc
     7801 tttgggtgaa gcagctgctc agctgattgg ttacgtggga gatatcacag cagaagatat
     7861 tgataagaat ccagaattaa gcagtaatgg aaaaatcggt cgctcaggtt tggagatggc
     7921 ttttgataag gatcttcgtg ggacaacagg tgggaaatta agcattacag atgcagacgg
     7981 tgtagagaaa aaagttctga tcgaacatga agttcaaaat ggcaaagata tcaaattgac
     8041 aatcgatgcg aaggcacaaa aaatagcttt tgacagtcta ggaggaaaag ctgcatcaac
     8101 tgttgcgaca acgccaaaaa ccggtgatct tcttgcgctt gctagctctc caagctatga
     8161 tccaaacaaa atgacaaacg ggatctcaca agaagattac aaagcttatg aagaaaatcc
     8221 tgaacatcca ttcatcagcc gatttgcgac aggttatgct cctggatcta cgtttaaaat
     8281 gattacagca gcaatcggtc tcgacaacgg cactatcgat ccaaatgaag tgttgacgat
     8341 caacgggctt aaatggcaaa aagacagttc ttggggatct tttaaaacaa cgcgtgtcag
     8401 tagtgatgta tcacaagtag acttaaaaac tgctttgatc tattccgata atatatatgc
     8461 ggcacaagaa acgttgaaaa tgggtgagaa aaaatttcgt acaggcttag ataaattcat
     8521 ttttggtgaa gaccttgatt tgccaattag tatgaatcca gcacaaattt ctaatgaaga
     8581 tagctttaac tcagatatct tgctagctga tactggatat ggacagggcg aacttctaat
     8641 tactcctatc cagcaagcag caatgtattc tgtttttacc aacaatggca cacttgtcta
     8701 tcctaaattg attgcagata aagagacaaa agataagaag aatgtcatca gcgaaacagc
     8761 agtacaaacg atcgtgccag atctgagaga agttgtgcaa gatgtaaatg gttcagcaca
     8821 ttctctttct gctttaggga ttccgttggc agcgaaaact ggtacagcgg aaatcaaaga
     8881 aaaacaggat gtaaaggggc aagagaacag tttcttgttt gctttcaatc ttgataacca
     8941 aggttatatg atggtcagca tgttggaaaa taaagaagat gatgattcag caaccaaacg
     9001 agcatcggaa ctattgcaat acctcaacca aaattatcaa taaaaaattg ctttttaagt
     9061 acagtaaaag gactgtggcg ttatcgtcac agtccttttt tcaaataaac ggttttcacg
     9121 atgtctcttt cacaacttct ttttgattta ctcacacttc ataaactttt tttgtaaaat
     9181 atttgagaac aagtggagaa ataagtgtac ttaataaaat cacgataact aaaggtgaat
     9241 agtactgtgg ttcgatcaat tgactttgct gtccaatttg taaaatgatc aaagccattt
     9301 ctccacgcga aatcatacca gcaccgacca tcaatgaact atgttgagaa aaaccggcaa
     9361 tctgagcacc aaaataacct ccaagcaatt tggtcaaaat cgctacaagc gtcaatatag
     9421 aaataaagag tagttgttca ctaaagtcag aaaaatcaac ttctaatcct acactgacaa
     9481 aaaatactgg tataaatact gcatatccta aagcctctac attgtggtat acttcttctt
     9541 taacctttgt ctgactgaca gctatcccag caaaaaaagc accaatgaca gagctaagcc
     9601 caacaagatc cgctacgtaa gacattccta aacaaataac tagcgatacg atgataatag
     9661 aagaatttgc gtacactttt tctgcaaatg aaagtaggaa aggcgcaatc catttgacta
     9721 ataagaaaat aaaaacaaaa taaattagct gttcaatcaa aacaagcggt aaagaagcat
     9781 tgctagaagc ttcccccgtt agaaaagata ggctgaaact tagaactaaa acgactaaaa
     9841 tgtcatctac cacagaagca cccaaaattg ttgatccttc ttttgtattc actacgttta
     9901 gttcttttaa tacttctact gaaatactga cagaagttgc cgcaagaata atcccaaaga
     9961 aaatcgcttc atttcccgaa acttggaatg ctttgcctgt caaccagcca aaaacaaccg
    10021 ggaagatgat cccaagcaaa gcaacgaaca taccaggtcg gaaatatttt ttcaaaagag
    10081 ataaatcact ttccagacca gctaaaaaca ttaataagat cacaccaatc tccgaaaagt
    10141 catggactag aatatcaggt ttgacccaat tcaatccagc ttggcctagc aaaacaccaa
    10201 caagtaattg tccaatcact gctgggatac ctaatctccg cgagatatgt gagccaatcg
    10261 ttgttgaaat caatatcagg cataaaatac caataaattc cattctcatc attcctttgt
    10321 ataaaatata gcccgaactt agcataacat acattattga aaaaatagga aaatatactc
    10381 acaaaaaaac caacaatcca aaagattttt ttggattgtt ggtttttata cggtctattt
    10441 taataactaa aaatgattaa cgtatagtca tttttcttat tctgatgaaa ttgataatct
    10501 cctggatgcc catgaaaatc aaaataaagc cgaatatttg gaatagaagc atcaaacttt
    10561 tgaatggatt gaacaataag acgaatccgc caatcaacaa cagaatacta ctataaacac
    10621 tccaactttt agcttttgta ttcatgctga agaacaactg gaacaagctg ttgatgataa
    10681 cagctaatcc aagaagaatc ggcaggatag aaacgattgc aggtgcaaaa gcatagacga
    10741 tcagagctaa gatcaggaaa aaaagaccac tgaacagacc gatactccaa gaacctgttt
    10801 tccttttaaa acggtaagcc tcaaaaagat tcaacaaccc aagcaaaaca agataggcgg
    10861 tgatcagata accgataaaa tgaaaaacag cagaagggtt tagcacaatc gcaatcccag
    10921 aaataatata aacagcagct cttaataagg cgtatttttg aatattttgt ttaatcgtct
    10981 caaacatata agaaaacctc ctttgactta ttttaacgtg aactagtcat tttaccaaat
    11041 taaatgttac aaaatgagcg aaggagaaga atatctctgg aaaaatcaac ttctgaggat
    11101 cttttccatt tttttgcctt ttgctagctc atcgatcatt ttatctaaat aacgaatttc
    11161 tttcatcaag ttatcctcga tgtcttctac tcgtacacca caaacaacac ctgtaatcaa
    11221 ggaacgtgaa ggattgggga caggggcttc cgcaaaaaat tgttcgaaag tcacttgttt
    11281 ttgtagttga tattctagtt ctgtttggga ataacccgtc agccaacaaa tgatttcatc
    11341 tacttcctct tttatacgat cttttctctc cgcttttgct acatacatag gataaacgct
    11401 tgcaaaactt gtcgtaaaaa tacgattttg cgccataatc agtcaccttt ctttttttca
    11461 aattatttac tacttatagt atataagaaa aagagaagaa aaagcgatta ttcaaaaaaa
    11521 caaaaaggat tgtgacaaaa ttcttgtcac catccttttt tccgctctct gactttttac
    11581 aatcttcata gctcaagtgc gcatcagata atcgaatgct cctaaagctg cagtagctcc
    11641 tgaacccatt gaaacaatga tttgtttgta tggactatct gtacaatcac cagctgcgaa
    11701 aacgccgggg atattcgttg cgccattttt ctcggtcact atttcatttc ttggattcat
    11761 ttcgatcgtt ctatctagcc aatccgtatt agggagtaag ccgactagaa tgaatactcc
    11821 tgaaacagct agtgtatgca tctccatcgt acggcgatcg atataggaga gagattctac
    11881 ctgattcgta ccgctgattt ctttcgtcgc tgcatgtttg ataacagtga cattcgcaag
    11941 agagactagt ttatcctgta agatttgatc tgcttttaat tctggtaaga attctagaac
    12001 atatacatgt tttgctaacc cagccaaatc gattgctgct tcaacaccag aattaccacc
    12061 accgataaca gcaatctctt ttcctttaaa taaagggccg tcacagtgtg ggcaataagc
    12121 aattccttta tttttaaact ctttttcgcc tggtacattg atagaacgcc agtgcgcacc
    12181 tgtcgcgatg atggcggttt ttgctttaag tgatataccg ttagctaagc caatattaat
    12241 aaaatgttgc tctttattta aggaaacggc ctgttgattc atcataatgt cgatagggta
    12301 actacgcaca tgactttcta cttgctgcat caattttgga ccttctgtgt aagaggtacc
    12361 aatcatattt tcaatcccta gtgtttcaac gacttgtccg ccgaaagaat cagcgacaag
    12421 tcctgtacgg attcctttac gtgctgcata gatagctgca ctactagctg ctggtccacc
    12481 gccaatcact aatacatcat aaggttcttt ttcaaacaac tcttcttcaa tcaaagggcc
    12541 agtgattttt tcaacaattt gttcgatcgt catgcgtccg ctactaaatt cttctccatt
    12601 taaaaacaca gttggcactg ccatgatttt tttatcatcg atttcttttt ggaacatccc
    12661 accttcaatc atcgtatgag taatatttgg atttaataca gctaatatat tcaatgcctg
    12721 tacaacgtcg gggcaattat gacaagtcaa gctaacataa ctgtcaaaat gcaatgtttg
    12781 tgttattttt ttgattttaa gactcaaaga ttcactgatt ttcggtgccc gtccactaat
    12841 ttgtaacata gccagtaaaa aagaggaaaa ttcatgaccg agggggatac cagcaaaaac
    12901 gattccactt tctttgccaa ctggattgat agaaaaacta ggtgtgcgca tcgaatctct
    12961 tttttcccaa gagattttag gagacatttc tgctatttcc ttcgtaaatt cagctagttt
    13021 ttgactattt tcactattat ccaaactaac agaaaaaaca ataggagatt caatcagtgc
    13081 taaatattgt tcgagatttt gtttagtttc tttgtctaac atatccacca cctaaatctt
    13141 tccaacaaga tcaaaacttg gtttcaatgt ttcgccactt tctttccatt ttgccggaca
    13201 aacttcacct gggtgggtac gtacatattg agcagcgcga atcttatcaa tcagtgcact
    13261 agcgtcacga ccgattccat ctgcattgat ttccatagct tgaacgattc cgtctggatc
    13321 aataataaat gttcctcgct gagctaatcc ttgctcttca tccaaaacat caaaaatacg
    13381 agaaatctga tgagacggat caccgatcat cacgtattcg attttaccga tagcatctga
    13441 tgtatcatgc catgctttgt gagtaaagtg ggtatcggta gagcaagaaa agacttcaac
    13501 acctaaagat ttcaatgtac tgtattgttc ttgtaagtct tctaattcag taggacaaac
    13561 aaaagtaaaa tcagctggat agaagcaaag aatactccag ttccccataa gatctttttc
    13621 actgacttct aaaaattctc cttgatgata agcatgtgca ttaaattctt cgattttttt
    13681 cccaatcaat gacatagtaa aacctccaat aataattatt tatttataat tattgtaatt
    13741 tagttggagt tgcaaagtca atggatattt tgttatttaa taaagattac tcaaaaacga
    13801 aggttaatta taaaaataga agaggtcgca agaaaatgct actgctggaa atactcggga
    13861 taacgttgag taacagtttc ctgttctttc agcatcatgt gtaagtgcaa tcccgtttga
    13921 aatcgagctt cttctggttt tttatcaact aaagccttga gtaaatcata atgttgttcc
    13981 atgatcgttt cccatggaag cccctgaatg gtcactcgta accagcggaa acgttctaaa
    14041 tgggtattat ggtcatctaa ccagttccaa acttcttttc ttcctgcaat ttcgaaacaa
    14101 gcttcatgaa ataaattatc tgcacggaaa aaagcgcgtt cgtcatttat tttgactgct
    14161 ttttcttgtt cttctaaaat cgtttctagc actattcgtg tttgtgtgtc caatttggaa
    14221 caacattcaa tcatgatttg ctcttccaac tgttctcgga caaagcgagc attttctgca
    14281 gaaacaagat taattttgga aacatacgta ccactttgag gtatcgtata cacgagttct
    14341 tgctgacgta gttgaatcaa tgcttcgcga atgggagtcc ggccgatagc aagatgttcc
    14401 tccagtgcct tttcagatat tttccttcca ggttctaagt cagcatagat aatttgttta
    14461 cgaatcgctt gataagcttg tgattgcaag ctgcttttca tctttattcc tccaaaatca
    14521 tttctatgaa cgtagtataa cagaagaggt ctgaaaaaca atctggtatg tcacattaac
    14581 tagtaaattt gtataaatag taaaattttg gttgacatag cgatttttat tgcataaaat
    14641 tcacttgaat acaaaaacta atatgttagt ttaggagggg aaaaatgatt gatttaaaca
    14701 actggaggaa ctttatccct gaattatctc aaaaagaagt agaaatacct cattttgacc
    14761 gtgcatcatt aagagaaaat ggacaaaaaa atcctgtctg gatccatttc ggtggcggaa
    14821 atctttatcg aggatttcat gcagaaatcg ctcaacgttt agcggatcta ggcgaattgt
    14881 ccactggtgt cattgtttgt gaaacattcg atgaagaaat aattgaaagg gcttaccaag
    14941 attttgatga tttgattctt gaagtggtca tgccaagcag tggagagttc gtcaaacgta
    15001 tattagctgc gacagctgac agtctgtatt gtcatccaga ttgttctgaa cactttgata
    15061 agatgattcg acactttgaa aatcctagtt tacaattagt tacttttgct attactgaaa
    15121 aaggttatcg attgaaagat acaaataata aatatatagg accgattgca gtcgatataa
    15181 aaaatggtcc aaagaagcca tcacatacaa tgagtattct tgctgtgcta ctttataaac
    15241 gttttttatc tggagcttgg ccgattgcac ttgtctctac agataatttt tcacaaaacg
    15301 gtagtcaatt acgtacttct ttgctaacga tcgcaaaaga atggcaaaag gaaggttatg
    15361 tacaaaatac atttatccaa tacttatcga atgaagaaat tgttgcgttt ccatggacga
    15421 tgattgatcg tatcaccccg aatccttcct tgtcagttag caaaatgttg gcaaaagagg
    15481 gcttttcaaa tatgtcgatt ttccaaaccg caaaaggaaa taatattgct ccatttgtca
    15541 atacagagga catccattat ttaatcatgg aagatcattt tcccaatgga cgtccgaaat
    15601 tcgaaaaagc tggggtattc ttgactgatc gtgcaacggt agataaagca gatacgatga
    15661 aggtgacgac ttgccttaat cctttgcata cgtctttagc tattatgggt tgtttactgg
    15721 ggtataggag catagctgag gagatgaaag atccagattt atcgctgcta gtttctgaaa
    15781 tcgggtacaa tgaaggcctc ccagttgtgg agtctccagg tatcattgat ccaaagatct
    15841 ttctggaaga agtaattact gtgcgctttt ctaatccaaa tattcctaat atgcctcagc
    15901 gaatcgccac ggatacctct caaaaggtgg cgattcgtta tggtgagacg attaaaaaat
    15961 atatggaaat agaagttaaa gacccgcaga cacttgtatt cataccattg actctcgctg
    16021 cttggcttcg ataccttatt ggcattgatg atcaaggaaa accattcatc ccgagtccag
    16081 acccactatt gacagacctt cagcataagc tttccgatat tcaactgggt acgcaagata
    16141 catcacatat tcatgagaaa atggctccta ttttgtcaaa taaagaaatt tttggtgtag
    16201 atctttacca agcagagctt ggcagaaaaa tagaagaaat gttcatcaag atggtagcag
    16261 gaccaaatgc cgtacgaaaa acattacagg attacttaca agaacatgga ggaaatttat
    16321 catggaaatg acttttagat ggtacggatc acaggaagaa aagattacct tagatgaaat
    16381 cagacagatt cctgcggtca aagggattgt aggcacattg atggatatac cagtaggaga
    16441 ggtatggcct agggagagga tcaaagaact aaaagaagaa attgagtctc gtgggttaac
    16501 actaaaagta attgaaagcg tcaatgtgca tgatgccatt aaaattggat taccttcccg
    16561 tgagcagtat atcgaaaact ataagcagac aatccgaaac ttggcagaat atggaataga
    16621 agtcatctgc tataatttta tgcctgtatt tgactgggtg aaatctgacc ttgactaccg
    16681 cttagaagac ggctcatcca cgttagcttt tatatctgat gatattccag atgatccaag
    16741 agaaatcgtc gcgcgcatcg aacattccag caatgaattt ggattgccgg gatgggaacc
    16801 tgagcgctta gctcctatca aatccttgct tgaagcctat gcatcagtag acgaagaaaa
    16861 acttcgagaa aattttgcct attttctcca atcaatcatc ccaacatgtg aagaggtagg
    16921 ggtcaaaatg gctgtacatc cagatgatcc gccatactcg atttttggat tagctcgaat
    16981 cgtaaagaat cgagaagatt tagattggtt gtgtcgcata gtagacagcc cttataacgg
    17041 aatcactctt tgtacaggga gtattgcaga agatccagaa aatgatgtat atgggatttt
    17101 agcagaattt tgccaaagag atcgaatccc atttgcacat gttcgaaata ttaaattttt
    17161 agctaatcga gatttctatg aggcaccaca taaatccgaa tacggttcat tagacatgta
    17221 ccgcatacta aaaacaatgt atgacaacgg atttaacgga tacatccgtc ctgatcatgg
    17281 aagaatgatc tggaatgaga caggaagacc aggatacggc ttatatgatc gagcattagg
    17341 tgctgtttat ctaaatggat tatgggaagc aatcgaaaaa ggaaacaaaa gtaaagataa
    17401 ttagtgaaaa aaactgtaat tttattatgt aaataagaag gatgttcaaa ttcttgatac
    17461 ataaatccgg aggttgttaa taagcattcg gatttatgta tcttatttgg tctaggaagt
    17521 aacttgattt tcttttttcg attgatccat gagtgcttct tcttttaatt caaagatata
    17581 ttctgagatc ctcataatca cttttttcca gtcttctggt gtgatgattc cttttaaaat
    17641 atagattttt ttgatatgag aaggcaattg tttcaaaggg cagtcgctga taacgatgtt
    17701 gcagttctcc ataaaatcat tttgtatttt gatcgattca tttgaaaaaa tttgttctat
    17761 cttaacgatc agatctttac tgatataaaa atcacgcgta tagttcacac caatcacaat
    17821 tcgcggctgt tttttgtagc gatcatacaa atgtactagg tcttcaacca tccattgcac
    17881 attttccttt tctaaaataa ctggtaacaa gtgttgattt tgttctctga aatccatata
    17941 aaattgttca atggcggttt ggacttcttt caatacgcta tgttcttgat aaagcatgaa
    18001 agtaggaagg ggcgtatttg gttgattgaa gttaagaaat ccattataaa gtttatttcg
    18061 tgcgaatgcc aatgagtaaa gaatcttttc tttttcaggt ataaacaaat caaatacagt
    18121 acaaagggac tccaccattt ctcttgaata aagaacatga ggaacgtttg ctttttttaa
    18181 aagtttgtat tgctccaagc ttgtttcttc cgattcgatt ttcgtgatag aaagtcgagc
    18241 taaaatattc actaagatgc gttgttcgcg acaaattggc agattaggtc gcaaaatatc
    18301 tacagagaga tcaataaaaa agtcaatata ttcatactct gtgaattctt tttgtacgtc
    18361 tttcacagaa gttgcaggaa aattctcttt acatattttt aatagaaaat ataatttatc
    18421 tatcataccg ctatttagtc ggtcaagtac ttctttttta aaaaaagtat tcatcataaa
    18481 agccactact tgcggatctt catcataaaa ttctgtagca gtacttgaaa agatgttcca
    18541 ataaatatct aatgctgcat attgaatttg tacctctttt ccagaaaaag actttctgcc
    18601 attattagaa aaggagatag acaaaccgta ctatgctaaa aatgcattaa tctttttcat
    18661 tttcgtatac aaataagagg cactatagtt tgtttgctga ctgaaactga taatcgaatt
    18721 tgtctgacag ctgaacaaag aagtcaagat ctgataactg actgattcgt tgcagtatct
    18781 tccaaataga cgataatagc agtaagccgg atcaattcct tcaaaattca actttaaaaa
    18841 aggtttttgc ttatcaatat gcagttctgt tagattgaga cgctcaaagt cttgttctaa
    18901 ttctttgatg tatagtaaaa aatttgattc agacatatgg aaatgatctg ctaaatattg
    18961 tgtagtaata aagaaacgat gttcagatag gaaaagaaaa atatctaatt ttgtattgct
    19021 ttttttcttc aagataaacg ttttaatcgc ttcttgagtt tgcatgaaag aggctccttt
    19081 ttacttaaat tgttaaaact tgaaaatatt actgtttttt tcataaattt agacaaaaaa
    19141 acagtaaaca tataggtaga atctctacta tcttatttct tgcatacaaa aaaatcaagg
    19201 agtgagagag ttatgagata ttcaaccatc ttaatatcaa catttgcagc cttaagctta
    19261 tcgcttacta taaatcagac agtccacaca gaggagacag aaacagccaa atggacagaa
    19321 accaagtggg ccaacgtcaa tcgaattacc tttcaggatg aattttcatc cttcaattca
    19381 ggagtcgcaa aattaagaaa aggacaaaca gcgaccatca aagcaaaaat tgactattcg
    19441 ggagacttag cacctatact acaatcagct gttacatttg agaatgttga tcccactttg
    19501 tcgattggct atgacgagaa cactttgact atccaacaca agcaagcgat atttaccttc
    19561 accgttacat taaatcagga cttgttaaaa ccagcgcttt ttactgtcaa ggtatcagat
    19621 ggactaccga acgatcatca tttaacgccg tatagtcagc ggcagacaat tgagcaagat
    19681 tcagccatcg actcaggagg agatcttgtt gaagaaccaa cagataaacc agaaaatgaa
    19741 aataagccag aagtaccgcc tacagaaaat ccagacggag aacagaaacc ggaaatagaa
    19801 cctggagaag aacccgatac agaaactcaa ccagagccag acaataaatc aaaacctgaa
    19861 ataacccctg gagaaaaacc agatgtaact ccagaaccag atacggattc tggaaaccaa
    19921 acagtaccgg aaacaaatcc agacacagat aatgaaactg aaaatccaga aaaaccagag
    19981 gtagatccag aagaaaaacc agatgtgact ccagaaccag atacggacgc aagagaccaa
    20041 ggaataccag aaaaaataaa caaaaaaaca attcaagagg atggaaaaaa agagagtaaa
    20101 aaatcaaatc tagcaattct aaaaataaat gaagagcagc tgaataaaaa atcacgaata
    20161 tttgatagcg cccaatcagc tgaaacctta aaaagtagca aggatacaac ctttgctgtc
    20221 ctgaaacgaa aaataaacag ctaccaaaat ccggagagtc acaaaacaaa gttatactgt
    20281 ggagcggaat cattctatta agtatagcaa caatgctttc tgcaaaaaga tttaaacaaa
    20341 acagatctct ctaacatttg aataatgtct gtgaacgcat ttttcaaata aaaagaaata
    20401 tccagaaaat gaccccaaaa taccagattg aaatctgata tttggggtcg ttcatacttt
    20461 atctttcttc atatttattt taagggatat ctgtttcttt tggaagatgg ttcgggatct
    20521 ttttcacttt caatacatct aaaaagaagg taaagatcgg aatgccgaca atcaagcccc
    20581 aaacgccaaa gaaccgttcg ctaacaagta agaccacaaa tgtataaaaa atcggcagtt
    20641 ctgttttgct ggacatcaac ttcggattca gcacataaga ctcaattaga tggacaatca
    20701 aaatcgtaat caggatataa acaacatctc ggatgcctcc ttgggaataa gctatgaaag
    20761 atagaggaat acaagaaatg ataacacctg ctactgggat cagacttaaa atgaaaatca
    20821 tgatcgctaa actcagcagc tgatgaaagc caaatacagc caaggcgatt gtagtgagca
    20881 acgtatttaa aagagcgaca acaaattgag cttctaatac caaaccaaat gtattgacaa
    20941 acttatcggc aaaatagtaa atatcttgaa agaaccaaga aaattcactt tttaaaaaca
    21001 atcttgagaa tacaattgtt tttttctttt caatcataaa aaagaaactt aagatgaatg
    21061 acatagcaaa cgccactgcc atttttccta tatcctgtaa atagccaagc gcaatcgaag
    21121 cgccattttg aagctgttca aaaaaatcgt ttcgctcaat ataagtatgg atatattgta
    21181 aaacaggatc tgcatctttt ggctgatgct cgtaaaaatt aataacggac tggatcatgt
    21241 caaatgtttg atgaataagc atcgggatat actttgtgaa tgccagatag ataaggtaaa
    21301 cgatcagtgt ataaatcatg atagctaaaa cacctgtagg gattcggaca aatcgctgaa
    21361 tgatttgaac aagatgaatc atcaaataag taaagataaa tgtgagcaaa atggttgtaa
    21421 tcatacttct aactaagaaa agaacaaaaa cgacaaataa taaaacagtg agacggcgta
    21481 ttttttcatt cgccaaaaaa cgctgataaa cggtcaaatc gacaacctcc aaataacaaa
    21541 aaataaacac gttattcatt atatgatgga atatgaaaat aagaaagagc aaaaagaaaa
    21601 accgctaaat gacgttatct tatgagttgg ttttcctcat aaaatcgttc atctagcagt
    21661 ttcagccctt tttctggtct tgatgaaaat tatctagcat ttttcgggtc agatgttgca
    21721 gtgtatccaa ttcttcctgt tcaagtggaa gataagactt gatcttttgt ggaatacctt
    21781 ctgcttgttt ttgcaacgca gcaccttgag cagtcagcgt aacatttacg attctttcat
    21841 cacccgtttc acgctgacga ttaatataat ttttttctgc taactttttt agtaagggag
    21901 tcagcgtacc agaatccaga cacaaatcat ttcctagctc tttcactgaa gtctttttct
    21961 tttcccataa aactaacatc acaagatact gggtataggt aagattcagc ggcttgagga
    22021 ggggagtgta gtgtctaatg atttctttag aggcggcata taaaggaaaa catacttgat
    22081 taactaaata tagatcttcc atttttccac ctccgctgtt ttactatagt gtatcatagc
    22141 ggatttacac aaaaaagtct attcactaac tgctttcaga gtaacttcta tatttccagc
    22201 tgtagctttt gaatacggac acactttatg cgctgcctct aataattctt gcgtttcttc
    22261 cagagaaaga ccttcgatag atccttcaat ctctacacct aagacaaagc tcgtttcact
    22321 ttctgaataa agggaaactt gtgcactgac agtagaagcc ccagagatat ttttttgctg
    22381 tttgatcaat tctaatgcac tgttaaaaca tgcactgaaa ccagctgcaa acaattgttc
    22441 agggttggtt gcattttcga cgcgtttacc aggagctgca atattcaatt cgaatgtacg
    22501 atcgggatta tgcacttctc cagagcgtcc gcctgtgttg atcattttcg tagaatacat
    22561 ttttttcata aaattaccac ctttaattat attttataca attgaatttt acacaatata
    22621 attgtggaaa gcaaagaaat ggattggcat aagataaata agagaaagca catgaaacag
    22681 acgcgctttc tcgaatagca aacatataca aaaaatatca gagacaaaaa ataatctcat
    22741 cataaacatt acatatattt ctcaaaaagt tgttttcttt cttcaaaaat tacttcacga
    22801 tggacctgat gaagcatcca taaataacca aaaggatctc tgaacattga gttagtcaca
    22861 ccaaagtcca tcatttctgt catttcttga atctctacac agccatttcg taatgcttta
    22921 ttatgtgtgt cctcgatatc agagacgatg atattgaacc agatcgtatt tggatgttca
    22981 gcagtaggag cagtcaaacc aagagacgtg ttttcatcca gcatatggaa tctcgtacca
    23041 tacaaggtaa aaatgacttc attattgcct ctagggtaat ctgttgcctc aatcagttgt
    23101 atttcatcaa agattgtttg atacagttct agtgctttca aactatcatt taatacaaaa
    23161 tcgatttccg ttcctttatg cataaagatc tcctctcctt ttcagtcgaa cagttactag
    23221 attcttttat tataccagct aaagaaaacg cattcaaaaa aatagcggat ttacttacca
    23281 actcattcga ttggatgata agtaaatccg cgtcccatta cttctgctac gctgctgaca
    23341 atgacaaagg cacttggatc gatttcttct atcaatggtt tcattcggga aaattcatga
    23401 tcagtcacaa cgatcaataa aacctctttt gactttcgat tatacccgcc ttttgcctct
    23461 agcagggtaa ggccacgtcc aatctcagca cttaagcgaa ggcggatgtc ttccaaataa
    23521 tgttcactca tgaccataac agatttcttt cgattgatac ctgtttcgat ataagtcatg
    23581 acaattgaag tgattgcaat agataaaata gcataaagaa actcttctat tccaaaaata
    23641 aacagattaa gagaaacaac gaatgcgtct gtaaaaaata agccaatcga agtattcaag
    23701 tggaaatatt ttttaaaaat gaggggaggg atcgtcgtac cgccgctaga agagttgttt
    23761 ttatataaaa tcgcaactcc taaagcaaaa atcgcacttc caaaaatgac agacaacaac
    23821 cgatctgaag taatcattgt ttctggaact attgcaatga ttaaaggaaa aaccaagctt
    23881 ccgaaaagta ctttaaaaaa gggtttttta cctaaaaata gaagagctag taccaacata
    23941 acgatattca acactaaaat aactatagct cggtcaaagc ctaaagcagc ttccagtaat
    24001 attcctagac cgctgacacc tccagcagca atatgatgag gccctaaaaa catattgata
    24061 gcgactccta atatgaagag ggcaaaaata atcttaatgt atgtccatat aaattgtctc
    24121 gtttctttca tttattcact tccttaattc attaataata ctcttatctt attataactt
    24181 acttttcacc ttaagttaac tttaattaat aaaaaaatta ggctagtcta aattattatg
    24241 tttcattctt ctagaatata cttctacgcc aaaaactgtt aaaaaacttt tactttagaa
    24301 aattggagaa attgatcgct taagataaat tcaggacact aaatagtaca ggaagtagac
    24361 taaaactttt aaaagtttta agtctatcta tttggcaagt ttaaaaaata aaaattcggt
    24421 atcaaaaaac tgttaccgat aacatttttg aaagcgttgt cttttgcttc tctatcactt
    24481 atagtgatga cgtcatatta aaacacaagg aggaaatcaa tggatacagc tgcaatttat
    24541 catcgaccgg aaagtgaata tgcatttcta tatacgaata caagatttcg tattcggctt
    24601 cgtactagga aaaatgatat caaaaaagta tatgtgctat gtggagatcc atataccata
    24661 acaactgaaa aatggtatca aaaacaacga ccaatgaaaa aatgtctaag taccaatgtt
    24721 catgattatt gggaaattga agtgacgagc gaaacaagtc gcttacagta tgcgttccat
    24781 gttgttgggg aagataacac ggactgtttt tacggtgatc aaggaatttt tccttatcga
    24841 gaaaatgtga ttactgaacc aaatttttat tttcgaatac cttattttca tcaaatcgat
    24901 cgattcacta ttccagaatg ggtaaaagaa acagtatggt atcaaatttt tcccgaaaga
    24961 tttgcaaacg gggacaaagc aaatgacccc gaacacactt taccttgggg aagtaaagat
    25021 ccagaccgag aagacttttt cgggggagat ttgcaaggtg tgatggatca tttggattac
    25081 ttgacggacc ttggcatcaa tggcatctat ttttgtccca tatttaaagc cacatccaat
    25141 cataaatacg atacgattga ttattatgag gtggatcccg cttttggcga taaaaaactt
    25201 ttaaaaaact tgattgatga agcacataaa agagggatac gtatcatgtt cgatgctgta
    25261 ttcaatcata tgggtgtcca ttcaccacag tggcaagacg ttctcaaaaa cggagaaaaa
    25321 tcgatctata aagactggtt ccacatccgt tttttcccag tagattctta tcagatgact
    25381 gacttaccag aaactgctga aaatatccca tatgatactt ttgcttttac tccattcatg
    25441 ccgaaactaa atacagcaaa tccagaagtg caaaaatatt tgctggatat cgcaacttat
    25501 tggataaaag aattcgatat tgatggatgg cgtcttgatg ttgctaatga agtcgatcat
    25561 catttttgga aaaaattcag agaagcagtt acagaaatca aaccagacat ctatatcctt
    25621 ggagagattt ggcattcctc tcaagcttgg ctgcaagggg atgaattcca tgcagtgatg
    25681 aattatgcat ttacagattc gattaaagat tattttgcaa aaaagaaaat cacagcttca
    25741 caaatggtca gtggaatgaa tcatcagcaa atgctttaca gagatcaggt gaacgaagga
    25801 acattcaact tattagattc tcatgatact gccaggatct tgaccctttg ccaaggtaac
    25861 aaagaattga tgaagtctgt gatggccttt atgtttcttc aaaaagggtc tccttgtatc
    25921 tattacggga cagaaatagg gatgactggt gaagatgacc cggattgccg caaatgtatg
    25981 atatgggaga aggaggaaca agatctagag ctattcggtt ttataaaaga acttgtttct
    26041 ctaaggaaac agttgtctaa gattatttct gaaggttcta ctcagtggct aatagtaaat
    26101 gatcgtgaag ataagctcta tttcacacgg aaactagagg gacagatcat ctatgtttac
    26161 tttaatcagt caaaagaacc ttgggtagta gaacaggaaa atgaggtgat tcttagtcaa
    26221 aattgtcagt tgttagaaga cgggaaagca gagatacgac aatacggatt tttgatcatg
    26281 tgttgaaaac tgttaccggt aacaacaaga aagcgtttgc aaatgaagat ttgtgcccat
    26341 tataataagg gtgtaacagc acgttgaata caaaggagga aatgaagatg aaaaaaagaa
    26401 gtgtgaaaca gttgggttta gggttaatct ctttaggaat cttaggcgga ttagcggctt
    26461 gtggcaatgg taactcttca gcagaagggg aagccgatga aggaaaaacg ttaacagttt
    26521 ccgttgattc tggatataaa gattatataa acgaaataaa aaacactttc gaaaaagaaa
    26581 acgatgtgaa aatcaagcta gtagaaaagg acatgttcga tcagttggaa tcattagcgt
    26641 tagatgggcc tgctggaaag ggacctgacg ttatgatggc agcatatgac cggatcggtg
    26701 cgttaggaca gcaaggacat ctggcggaag taaaactggg aaatgaagca gcttacgatg
    26761 aaacagacaa agcccaagtg acttatgatg gaaaaatcta cggagaacct gcagtaatcg
    26821 agacccttgt tttgtactat aacaaagatt tagtcgatac agcaccatca acgtttaaag
    26881 atttggagaa tctatccaaa gacagtcgtt ttgcttttga gtcagaagca ggaaaaaata
    26941 caggattttt agctaaatgg actgactttt attattccta tggtttaatt gcaggttacg
    27001 gtggctatgt atttggtgat gatggcacaa atccttcaga tatcggtttg aataatgcag
    27061 gtgctgtaga aggaatctct tatgcaacag attggttcaa aaatgtttgg ccaaagggaa
    27121 tgcaagacat aaaaagtgca ggagacttcg ccagccagca attcatgtcc aataaaactg
    27181 cagcaatcat tgacggtcca tggcaagcgc aaacatacaa agaaaacaat atcaattatg
    27241 gtgtagccaa aattcctact ctaaataatg gacagcctta tcaaccgttt ggcggaggaa
    27301 aaggatgggt agtcagcaat tatgctaaaa acaaagacct ctctcaaaaa tggcttgatt
    27361 atgtaacgaa tcaggaaaat caagaaaaat tctttgaaat ggtaaatgaa atccctgcaa
    27421 accaacaagc tagggaaaca gcaaaggcta aaaacgatga attaacaaca gctgtgattg
    27481 aacaatatga aacagctcaa gcgatgccaa acatcccaga aatgggcgaa gtttggacag
    27541 gtgcagaaaa cttgatgttc gatgcagcat caggttcaaa aacaccaaaa gaatccgcag
    27601 atgaagcagt aaaaacaatc agtgaagcca tagaacaaaa atactgatta aaatgataac
    27661 cgtccatttt tataaaaaat ggaacaggtg cttcagataa aagtggcaag agcgagatgg
    27721 aaaattatct tgctcttgtt gccattatct taaaagcagt ttgcggttta gcaagtttag
    27781 agggggcatt cagatgcagc aagataaaac aagcaatatc aacgaaaaaa aaatcacgct
    27841 ttgttcactt attccaggga tggggcagtt tgtaaatggc caagctttta aaggtatcgt
    27901 ttttttcgcc atattcgtcc tattcattgg tcagatgctt ctgggcggat ttcatgcatt
    27961 ggtaggattg gttactttgg gaagtatacc aatggaagat cattcattat ttattttgat
    28021 tgaaggcact ttgcaattca tcattacaat cattttcttg attttttacg gtttgaatct
    28081 tttagacgct tatcgagtag cgaagatgcg tcaagagggc aaaaaaatca atcggacgat
    28141 gaaggaagtc atacataata taggtgatga aggttttcct tatctattga cacttcccgc
    28201 ttatcttctc atgattttta cgatcatttt cccagtccta gttacattgt tcactgcatt
    28261 tactaattat gacttcaatc atattccacc agccagttta attgattggg taggggctaa
    28321 aaactttttt agtatcttct ttttaagctc atatcgtaat actttttttg cagtcttttc
    28381 gtggaccgtg atttggactt tatgtgcaac aactttgcaa atcacccttg gtattctcac
    28441 agcggttgtt gctcaccaga aatttattaa attcaaacgt attttcggta tcattttctt
    28501 attaccatgg gcggtcccag cttttattac tatcatgagt ttttcgaata tattcaacga
    28561 tagcgtaggt gccatcaata ctcaagtgat tcctttcata aaccagcttc cttttgtaga
    28621 tatcagtgca atctcttgga aaacggaccc gaactggacg aaagtagcaa ttatcttagt
    28681 gcagggctgg ttaggatttc cctatatcta tgtgatggtt acaggaatct tacaatcgat
    28741 ttcagaagac ttatatgaag cagcaaaaat cgacggagca aatgcatggc agcgcttttc
    28801 aaacatcacg cttcctgctg tcttcctagt ggcagcgcca acatttatta cacagtatac
    28861 ggggaatttc aataatttct ccatgatcta tctgtttaac aatggcggtc ccggaagcgt
    28921 aggcggagga gctggttcta ctgatattct tatttcctgg atctataaac ttacgactgg
    28981 aacttctccg cagtattcta tggcttcagc aatcacgttg attatctccg tcatcgttat
    29041 ctgtgtgtca ttgctggtat ttaaaaagac aaatgcgttc aatatggggg attaacaatg
    29101 aaaaaatttc attcgagtgc tcgattccaa aaacgacttt ctcacttttt tacttacttt
    29161 tttcttttaa tactgtcagt cattatcatc tatccgcttt tgatcacagc aagtactgcc
    29221 ttcaagtcag gaaatattgc agcttttagt ttagatcttt caagtgactg gactttagga
    29281 aactttactc ggctattcag tgaaacactt tacgggactt ggtataaaaa tacattgatc
    29341 atttctgtcc taacaatgat cgtacaagtg actgtagtaa ctttggcggg ctatacttat
    29401 agtcgctatc gttttatcgg ccgcaaatca agtttgatgt tctttttagt gattcagatg
    29461 gtaccgacta tggcagcatt gactgccttt tatgtcatgg ctttcttatt agaagcgctc
    29521 gataagtact ggttcttgac aatgatctat ataggcggtg gaattccaat gaatacttgg
    29581 ctgatgaaag gatactttga cactgtacca atagatttag atgaatctgc taaacttgat
    29641 ggggcagggc atttcaggat ttttttccag attgtattac cgcttgtcaa accgatgctc
    29701 gccgttcaag cattatgggc ttttatggga ccttttgggg atttcatgtt agctaagttc
    29761 ctgcttcgaa cacctgaaaa tcagactgtt gctgtcggct tacaaacatt tatttctgat
    29821 gtgacaaacc aaagagtctc tctttttgct gctggggcaa ttttgattgc actaccgatt
    29881 tgtctattat tcttcttttt acaaaagaac tttgttaccg gcctgacatc tggcggaaca
    29941 aaaggatagg agcagagtat catgcaaaca tttccgttaa actatttttc cgcattacgt
    30001 acgccaactc aagtgtttgc gggacgcaaa ctattatcat ggcctaaatt tttcttgata
    30061 tttgtatttt tagtttcctt gatggtcatg cctgtgactc ttttttatgc caatcagatc
    30121 caagcgattc cattagaaca atttctatcc gttcattcgc tgatcgatga acaaggaacc
    30181 caaaaatttt ctgaacttga attatctgaa actgggttac aagcatcgca acaaacgata
    30241 gctgtgaccc ctgaaatttt ggtaggtgtg tctttatctg agaaacaaca atccgatcat
    30301 ggaactttta ttgattttga gaaggaacaa tgggtgatcc aacaaaagga taaatctggt
    30361 atacgccgct atacgatgaa ttatagccca tctttccaac cagattctgt acgtacgccc
    30421 gaagatttcc aacgattttt agaaagagaa ttttatgcca gtaatcgtcc aacaatcatt
    30481 ttatcttata gtttaagtct tggtcttgtc ctatttgtca tgacgagtct cattttattc
    30541 ggggcttcct ttttcttgtg gatgacaaga aaaagccaac tttcatccat tcatacattc
    30601 aaagagagtg caaatttgat gctgaatgtt atgggaatag gttccatggc agcagcagtt
    30661 gtagggttta tccactttga ctttatcttg atgctaagtg tccaaacaac gataactgtc
    30721 ttgctgcttt tatgggtttt tgtcaaaaca agattcaaag ataagcgtgt cgaatgacaa
    30781 gtttaagcga tttatgcgac aatgaatgtg aaaaaaatga aaaataaagt agtttttgaa
    30841 aaatttctga aaaaattaaa cttcttagtt gattcttttc ttttttagta ttaacgtaat
    30901 agggtagttt ttttaaggag gaaaatcatg ttagagaaaa ctttatacaa tcaattattt
    30961 tcacgttctt tctcgctccc tgtcgaagta aattattggg acggtacaac gaaacaatac
    31021 ggagatacgg acactcctcc ccaaatcaaa atcaatatcc atgaagaaat cccaatgaaa
    31081 gagattacaa gtaacgcttc tttggcacta ggagaagcct atatggatca tcgaatcgag
    31141 atcgagggaa gtatccaagc attgatcaac gatgcttatc agcaagcaaa cagcttttta
    31201 cgaggaaaag attatctaaa atggctgcca aagaaagaaa aacatacgaa acaaaaaaac
    31261 aaagaagata tccatgcgca ttatgactta ggtaacgact tttataaact ttggctagat
    31321 ccaactttga cttattcttg tgcttatttc aatacacctg aagatacgtt ggaacaagca
    31381 caaatcaata aagtccatca tatcttagac aaactcttta tcaaagaagg cgaaacgttg
    31441 cttgatatcg gttgtggctg gggaacattg atgttcactg ctaccaaaga gtataatgtc
    31501 aaggcaactg ggatcacact aagtgaagaa caatacgatt tgattaccaa aagaataaaa
    31561 gaagaacatt tagaagataa atgccgtgta ttattaatgg attaccgcga actaaaaggc
    31621 gaaacgtttg atcatatcac aagtgtaggt atgttcgaac atgtaggttc tgaaaatctt
    31681 gaaggttatt tcaaagtggt aaaagattta ttgaaaccaa aaggaacagc tttgatccat
    31741 ggaatcagcc gacaacaagg cggtgcgaca aatgcttgga tcaataaata tattttccct
    31801 ggcggttatg tccctggtgt tactgaatta gttgataata ttacaaaaaa cgatttgcaa
    31861 ctgattgatt tggaaagctt acgtcgtgac taccaattga cattagaaca ttggacaaag
    31921 aattttcatc aagtccaaga tcaagtcacg aaagaaatgg gtgattcctt ctatcgaatg
    31981 tgggatctat atttacaagc ttgtgcagct tcatttgaat caagtaatat cgatgtgatt
    32041 caatatttgc ttgttcaacc tggaaacaat gacatcccaa tgcatcgtgc ataattgagg
    32101 caaaagtact gtttaaagac tatttaaaaa gaagctaagt tttatgatgc tccagaagtg
    32161 aacttttttg tctaacttct aggattgtct ctaaagctta gtttcttttt ctttatattt
    32221 tcataataaa agtttggttc tttaattttt aaacatgaca gaaaattttt tcttcgttat
    32281 acttgtaata gaatactatt ttataacaaa ggggatcgaa tcaatgaaaa aaactgttat
    32341 ttatactagt ttatttgcag ctttgttttt agctgcttgt caatcaaata ccaatcaagg
    32401 cacatctggg aatacgtctt ccagtagcga acagcgctct tcacaggtat cggactcctc
    32461 aacaaaagca agcacatctt cgtctagcca gacaaaaagt tctagtgaag caagtactca
    32521 gtcagatatc aaagtgtctg cagctcgtgc gatcgaattg ttccaagata aatacccaga
    32581 tactgcaatt actagtttgg aattagatag tgattgggga tcttacttct acaagataga
    32641 aggtgtcgat gatcaaaaag aatacgaagc aagaattgat gctcaaaatg aaaaaatgga
    32701 gacagagaat ccagaaactc tagatcgaga tgaacaaaat ggtcaaaaga aaaaagaaga
    32761 tggtctggat gttgataaat tgatcacgat tgaggaagca gcaaaaatcg ccgtcgacaa
    32821 agtaggaagc ggtacggcaa cagattggga tttggataaa gatttaggta ctacttattg
    32881 ggaagtcaaa gtaaaagacg gcaatcaaag tacatcagtc aagatcaata gccaaacagg
    32941 cgaagtactg tcaactgaac aagatgatta agaatttctt cggaaaacaa gagttgattt
    33001 ttcttttagt catgatacac tagacaaaat aacttgtttg aaggagcgat ttacttgagt
    33061 ttagaaacga cctttgccaa tcatatcttt gccaatcctt tgatgaatgc atctggtgtc
    33121 cactgcatga ctacccagga attagatgaa ctggctcatt cagaagcagg agcatttatc
    33181 actaagagct gtacgatcaa tgaacgaaaa ggaaatcccg aaccacgcta ttttgatgtt
    33241 cctttaggga gtatcaattc tatgggactt ccaaacttag gtttttctta ttatctagag
    33301 tatgctcttg cgtatgaaaa agtgcaggaa aaccaaaatc aaccgttatt tttttccatt
    33361 gccgggatga gtgtccagga aaacttggaa atgcttgaga aaatagaaaa aagtgggttt
    33421 aatgggatca ctgaattaaa tttatcttgt cccaatgtgc ctggaaaacc acaactagct
    33481 tacgattttg aggccactta tgaaacactg aaagaagtat tcagcatctt ttctaagccg
    33541 ctaggaatca aattgcctcc ttattttgat tttgctcatt ttgatcagat ggctgatatc
    33601 ttgaatcagt ttccattgac ctatgtcaat gctatcaaca gtgtgggcaa tggtttgtat
    33661 atcgatacag aacaagaagc agtagtcatc aaaccaaaag aagggttcgg cggcattggc
    33721 ggagagtata tcaagccgac tgctttggcg aatgttcgcg ctttttatac acgtttgaaa
    33781 ccagaaatcc aaatcattgg tacaggtggg attcggacag gacaagatgc atttgaacat
    33841 ctgctatgtg gcgcaagcat gttacagatt ggtaccgagc ttcataaaga agggccggaa
    33901 attttttcta gaatcataaa agaattaacg cagattatgt cagaaaaagg atatacgtca
    33961 attgacgaat ttaaaggcaa attacgcacc atttcatagc aaagagacga aggtcatgat
    34021 tgatcttcgt ctttttttat aaaaaacact cgtctgttca ttcctgtgca agcgtactca
    34081 ttgtatgtta gacgaacttg tgggaaaata acagaggcaa aaaggaggat aatatgaatg
    34141 atgcaacaga attagcaaaa gagcttaaag aaaaagaatt tagttttcaa gaactagtta
    34201 cggatataca gaaaaaaata aagaagcaaa atcatgaatt gaatgcgttt gtcgcgcttg
    34261 aaccattcga gagtaattcc cacgagctat tgattcccca gtcagaaaaa gggccattgg
    34321 ctggtatccc atttccttta aaaatgctcg gtcaagaaaa aaagggatgg ctagctactt
    34381 caggatctcg tttatttgaa acacaccgag cttctcatac atctaattat gtgcggcaag
    34441 cagaagcgat aggtctagtt ccttttggac aaaccaatgc gccagagttt ggtttcaaaa
    34501 atattacaga cccagtcatc tatggcccag caagaaaccc ttggaacctt gaatgtacac
    34561 cgggcggatc aagtggagga gctgctgctg cagtttcatc aggaatcgtt cctttagctg
    34621 gtgctagtga tggcggtggt tctattagaa tacccgcttc gttttgcgga ttgattgggc
    34681 tgaaaccttc gcgagggacg atgccagttg gtccatatgc ttggagagga tggcaaggag
    34741 ctgctattga tttcggcttg acagtttcta tgagagacac ggaggcttta ttttatggga
    34801 tgagaagtat ccattccggt gcgccatatc aagtatcgcc agttgagtgg caaacacatc
    34861 caagaaaaaa acggttgaag atagcttttt gtgttgattc accgatccac tcacagatta
    34921 gtgaagaggc agtacttgct gtaaaaaaag ctgtagattt ccttggaaaa gaagggcatg
    34981 atttgacaga gattccttac ccactagatg gtcgtaaact gatcacgtct tattatcaga
    35041 tgaatggcgc agaaacagca gcaatgatcc gctcgattga aacaggcatc cagcgagctg
    35101 tcagaaaaga agaacttgaa cccatttctt ggactttgtt ccaatatggt cagaagctct
    35161 ctgccgctac ttacatcgat tctctgcatg tatgggatga agcagcaatt gtcatggaaa
    35221 acctacatca agaatacgat ctattccttt caccaacgac tgcatttacc gcccctaaaa
    35281 tcagcgaaga tttgcaaagt gatgcgataa gagcacagat ggaacacatc agtgattgtt
    35341 ctgaagtaga aggtttagac gttgtttctt ccatgtttga ggagagcttg aagatcacac
    35401 cttatacaca gttggctaat ctgactggac aaccagcaat cagcttgcct actcatttga
    35461 caaaagaaaa catgcctcta ggaatccaat ttatggctgc cagaggaaga gaagatttgc
    35521 tatttcaaat cggctatcta tttgaagcaa atcatcagtt ccatttacca aatccatgga
    35581 aatagcagaa acaaggagaa gaagaatgaa gaaaaaaaga ttgtttgctc taataactag
    35641 tgcctttttt attttaagcg cttgcggtac agctgccgct aatcaggaag ataacagctg
    35701 gagtaatgta gaaaaaaaga aagaattagt agtagcgact tctggcacac tgtttcccgc
    35761 atcttattat aatgatcaaa atgaattagt tggttatgat gtagatttgg caaaagaggt
    35821 ggctaaacgg ttaaatgtca aaatctcctt taaagaatac aacgtggatg gacaaatcac
    35881 ttctgtttca aaaagagaat cagattttgc tgcgaacgat tttggtatca caaaagaaag
    35941 agaaaaaaaa ttctcccttt cagagacttt caaatattca tttgacagta tgatcgtacg
    36001 aaaaaaagat gattcaggaa tccactcact tgaagatctt aaagggaaaa aagcagctgg
    36061 cgaacccaat actagctata tgcgtttagc ggaaaaacac ggagctaaat tagtcacata
    36121 tgacaatgcc acgaatgatc agtatttaag cgatgtagca aatggtcgaa cagatgttat
    36181 tctaaatgat tattatctgc agaaaatggc cgtatctgct ttaccagata tccctgtaaa
    36241 aatactggag aacgtttatt tcaatgaaaa cgaaagtggt tttttattga aagaaggaaa
    36301 tgatgctctg aaaaagaaaa tcgatggcgt attaaaagag atgaaagaag atgggacgac
    36361 aaagaaaata tctgaaaaat attttcaaac tgatgtttca gtcaaaccga aagaaacgat
    36421 ggctgagtcg gtgagtgagt gatgtacttt cctctaattg atttttccct catgtggact
    36481 tcacttcctt tcgtactgca aggcttggta tacacattag ggattggctt cgtgtcgttt
    36541 cttttaggaa atctggtagg gttgcttttg acagttttag gtcttttgga ttggctgcct
    36601 ctgaatgtat ttattcgttt ttatttatcg ttctttagag gcattcccgc actagtcctg
    36661 ctgtttctgt tatattttgg gttaccttat caattaagtg ccttaacggc ttcagtcatc
    36721 tgctttacga ttaccagcag tgcatttatt ggtgaaatct atcgaggatc actagcaggc
    36781 gtttcttcag gtcagtggga cgctggttta gcttctggtt tttctttctt tggggtattg
    36841 aaatatatcg ttttgccgca agcttttcga atctcagtac cggcactcag taacgtagct
    36901 atggatctag tgaaaggtac ttcgttagca gcaacaatca cagtgccaga aatatttcaa
    36961 aaagcaaaga tcataggcgg tcggacattc gattattttt ctctctatat tttagttgca
    37021 ctgatttatt gggtcatttg tatcgggatc gaaaaagtgc aacagtattt agaaaaacgt
    37081 tctatgcatc agtcaatctg aaaaatagaa atggtgctag cgtggctggc accatttcta
    37141 ttttttgttt cttgtatatt ctgcctagta ttttaaaacc atttcatgta aaatgtaaat
    37201 cgaaaatatg ttcggaggta gaaaacatga agaccccgct aaccatcgaa atagaatcct
    37261 cgttatacca atattgcatc gagcaaggcg gcttggttgt agaagaagtc acgatgcctg
    37321 atgaccaagg aattgtagat acgcttagct gcttgacaaa atttgatgga agccgagaat
    37381 ggcgatgcta tgagctgaaa gtgacaaaag cagattttcg ctctacagcc aaactgtcat
    37441 ttgttggaca ttataattat tttgttttac caagtaaact atatgaagaa gtaaaaactg
    37501 aaatccctac aggaataggt gttttagtgt atcgtccgta cacggttgaa gaggagatgc
    37561 ctgcctctgg tacatttctg attgcgaaaa aagcagcaaa gaaagagctt gctgtaccgg
    37621 aagaagcttt gacaaaccgc ttcatggctt ctttattcag ggaagtaaga aaagcaaagc
    37681 aaatggagcg aggcgtaaaa tattttccaa cagatcaatt gtacaaagaa ttgaaaagac
    37741 gttcagaaaa tcaagatcca ttttctaacg aacgatatta tgaacggttt ttagaggaaa
    37801 tagctagtca ggcaatcaat gagttgcaag aagaagttat cgcgcttcag catgattatg
    37861 aatatttgag gcaacaacag cagatccgtc ggttgcctac agagccattg gagtgaaaaa
    37921 tatgtactat ccttatttaa gaggaaaaca atttgaccta ttagcattaa aagaagcact
    37981 gtcgcgagga ttgctctcca ataaaatcca accagtgatc gaaccagtac gtgattccgc
    38041 tacgcttaaa aatgtgatcg aattatttca aaaaaagcac catccaatcg ctgtgatcca
    38101 aaatccccaa gtaggacaat tcaaattatt cgatcagcat gtgcacagtt ggacagtcaa
    38161 agaaaatagc tctgtcgtcc ctgcacagat cttaacgcca gaaaatctca gtgaagtact
    38221 ggattcacct ccagcgtttc ttgttttcga tggacagcac tacccaaaag atacagaggt
    38281 gtggaaacag ttggcaggag ttgattcgaa atttttgata ccagatacta gtcgctttcg
    38341 catctggctg cccgaaaaca aaattgtgat ccgtgactct tttcaaacga gaaagcatgt
    38401 tgaaagttat gcagataaaa cagatgactt ttttagtgat gactatcttt ttttccacgc
    38461 agacggatat attggatttt ctgatttcac gatcgaaggt agccgttatt tcgataaagg
    38521 gttccctagc cgagcgcttg ctatccatct aacgtatatt gatgcttacg gcaatatacg
    38581 cgtgaaacat tttgtctctg acagtaacga ctctgctaaa gaccaagcat tgaagtttct
    38641 tgaagcagga gataaaatga aaaaatggat catgcgtcac catcatcaac tcttgattac
    38701 ttcaggaatg attgaattat tggctcttta ccagcaacaa aaattccctg gactgggagt
    38761 gttgaaaaag tggtcactta tgcatcattt ggaacttatt agtcacctgc tagatcatcc
    38821 aaaagattgg cttaaatatt attcaaaagt tcaggaacta tatgaagtga tccaatgatt
    38881 agataatgta aatgaaaaag gaatagaaaa gaggaaactg gatgtatatt cggcaaacaa
    38941 ggaaagaaga agtagaagaa gtggtagaaa tcattaatgc cgcagcggat ttcattgctt
    39001 cgcaaggctc tcctcaatgg caaaacgggc agaaaccaac aaaagaaacg attttgaacg
    39061 atattgaaag aaaagaaagc tatgtattaa tagtggaaga tcaaattgct ggaacagctg
    39121 cattagtctc aagcgtggat cccgtttaca caaaaataga tggtagttgg aaagaatcaa
    39181 ctggtcctta tttatcgatt catcgtgtcg ctttagcaga aagtactcga ggaaaaaaac
    39241 tagcaaaacc gttcttagaa catttgttga cgattgcagc cagcaaaaat atccaagata
    39301 tccgtatcga tacttatcca gctaatgaac cgatggaaaa gaccatctat tctgctggat
    39361 tcacttatca agggatgatt gaatttcctt ttgaacacgg cgaaagaaaa gcatatcaaa
    39421 taatcatcaa ttgactataa aatcatctga gcaaagataa agacattaac actactgaaa
    39481 aaaacaatca tatgatagcc aagaggttgt aacagaagtg gccagcttca aaaaacaaga
    39541 aagaatttcc gaaaatgctt ctcaaatttt tgtggaattt tagcgtattt tacgaaatag
    39601 ctgctttctg aaactccctt catcgagagg tcgtgacata gcttttgtca cgacctctcg
    39661 gcttatccta cgagtattat tcgatacatt tatatcaata atcctttttt tattttatct
    39721 gcagcttctt ggaacgctcc atcgtttgac acgactaaaa gtgaggggat agctttcaaa
    39781 cgtttcaact gtgctaaatc ttctacataa accgccagtc tggctgaaat ctgttcagat
    39841 gaatctccac gttttttcag gcgcgattgc aatgtttctt tagagatcgt aataaagata
    39901 ggacggacta ccgtcccgaa atactcatat aaatgccaaa aaccatttgc tgtcaaaacg
    39961 gcgtaacaat ttcctactgt cagtttcttt ttaatttctg ctttactgga accatattta
    40021 tgttgagcat attggtccca ctctgcaaac tcatttccct tgatcatctg attgaatgta
    40081 ttgtcagaaa caaaataata atcctcttga tctttttccc caggtcttgg tgatcgattc
    40141 gtgtaagtaa tgatcttttg ttccggctga aaaatagctt ctgcgagtga agtttttcca
    40201 gaaccagaag gaccgataaa tacatagcaa taattcattg tcatttctcc tttgatgatt
    40261 gaacaagtga aaaagctttg gaaaatattt ccaaagcttt taaaagtaac tttgcttttt
    40321 tgtatattat accagcaagc cagtcacaat agcacttaaa aagctgacta aagtcgctgt
    40381 tagcaaaatt ttcaatccgt gttttgcgac aagatttcct ttttcttcat ttaatccctt
    40441 catcgcacca gaaatgatcc cgatagaaga gaagttggca aatgaaacga ggaagacaga
    40501 tataattgct gttgtacgct cagtaaaatg gaaattacca tttgctaatt ctgtcatagc
    40561 aacaaattca tttgtaacca gtttagtcgc catgatacta ccggcatcca ctgcttcttt
    40621 ccatgggatt ccgctgatga aggcaagagg ggcaaagatg taacctagga tctcttggaa
    40681 agtgatgccg aatatcccgt ggaagatagc attgatcatg gcaatcaaag caacaaaacc
    40741 gataagcata gcagcaaccg tgatcgccac atggaaacca tcaagaatgt attctcccaa
    40801 catttggaaa aatgtctgtt ctttgttttc ttcaatgatc agctcatctt ctttttcttc
    40861 taatacatag ggatttacaa ttgaagccag aatataaccg ccaaataagt tcaaaacaag
    40921 ggcagtgatc acatatttag aatcgatcag tgccatataa gatccgacga tcgacataga
    40981 aactgtagac atagccgata cactcatggt gaacaaacgt ttctcagata ggaagggtaa
    41041 ttcctttttt atggaaataa aaacttccga ttgtcctaaa atagcagaag ctactccatt
    41101 ataagattcc aatttgccca tcccgttgat tttacttaat cctagaccaa cagctttcat
    41161 aaataatgga agaatcttga tatagcgtag aataccgata atagcagaaa taaatacaat
    41221 tggcatcaat acggaaagaa agaaaggtgc acttccttta tttgctacac cggcaaaaac
    41281 aaagtcaaca ccttgcccag caaaagcaag aagatgatca aacatttttg ccaatacaga
    41341 aacaaccgct gtaccaaaag ttgtacgtaa taatacgaaa ccaagaacaa gctgtaaaac
    41401 gaacatcaca attagtggtt tcaatttgat tgcttttttg ttactgctga tcaaaaaagc
    41461 aagccctaat gtgacaaata aaccaataat acctaataaa taactcaaat aatcactcct
    41521 attccaaatt ccgttttatt ttacctgttt tgcaaataaa atactaatct ttagtgaaat
    41581 tttcattact tttttagagt gaaacgcatt cattttccat tagaaaataa agcgaacaaa
    41641 ataaaaggtt taaaaagtgt aacgtcttag taaagtctat aaaaaaacga aactatcgat
    41701 taagctaata gtttcgtttt caacatttat aagtaaactt tttctattgg taatatagat
    41761 tttcggaagg gtagacaggt gcgcaggtaa tatcgattcc tagttttttc aatgtttgtt
    41821 catcattttt attgaccatc acagtagagt gggcttgtgc tccctcaagt tcagctagtt
    41881 tatcataagc aacttgagcg attggattcg ttactgcact gattgataaa gcgatcaaga
    41941 cttcattgat gcttagtgca tccaaagagg aatgaagtgt ctttgatttc aatccttgta
    42001 ttgtttcaag aactaatggt gacaataaag gaatgtcatc tgcgatatgg gctaaatgtt
    42061 ttactgcatt taagataact gccgctgacg catccatcaa tgaacttgta cgcccggtaa
    42121 tgatgacttc atctggtaat tcgattgcaa tcacagcaga aggatctttt gtaggacttt
    42181 gcgcttgaat cttatctgca tagtcatggg cagggactac cacgtttcgg tcttcaggac
    42241 gtaaaccgac ttcttccata atcagtttga ttcgattaac tgcttcttcg tcgatcaatc
    42301 cttttttgaa gtcgcattct gtttggaaat aacgacggat gatttcttgt ttagaggctt
    42361 cttggacaac ggtatcatcc acgatcccaa atcctacacg attcacaccc atgtcagtag
    42421 gagattgata aacagattct ttaccagtaa ttttttcaat aatacgtttg attacaggaa
    42481 atgtctcaac atcccgatta tagttcacag ctactttatt gtaggcatca aagtggaagg
    42541 aatcgatcat attgacatct tttagatcga ctgtggctgc ttcataagca atgttcagcg
    42601 gatgtttcaa cggaacattc catactggga aagtttcgaa cttggagtaa ccagctgcat
    42661 gtcctttttg gctttcatga tacagttggt tcaaggaagt agcgagcttt ccacttcctg
    42721 ggccaggagc tgtcactaca acgattggtt tagttgtttc aatatactca ttttttccaa
    42781 aaccatcttc tgagacgatt ttttctacgt tgactggata gtcttcgatt tctgagtgtt
    42841 tatagacctt gatgtttcgt ctttctagtt tattgataaa gactttcgtg gcaggctgtc
    42901 cactatagcg agtgataacg acactgttga ttaataagcc ataaccacgt aattcatcga
    42961 ttaaccgcaa gatatccata tcataagtaa tcccataatc accacggatc ttattacgtt
    43021 caatatctcc agcatagacg caaatcagta tttcagcttg atctttcaat ttttgcagca
    43081 atttgatttt cgcatcttct tcaaatcctg gaagtacacg tttcgcatgc ttgtcgtcaa
    43141 ctagcttccc accaaattct aaatataatt tgtcatagtg gttcactcgt tccaaaatat
    43201 acgctgactg ctcttcaata tatttttctg aatcaaaacc aatttttttc actaggttcc
    43261 ctccttaagt actaaagcat tttttcattt ttttgaggat tcgtcaactg gaagagcgaa
    43321 attcctcaaa aaaacaaaga aaatggttta aaccaacttg tctagatagt tattcattgg
    43381 tatgatagtt tttgataagg aaggtgctac atgaaaaaaa gacagaaaaa gaaaaacgca
    43441 tataaacact atatccgttc gatttttacc ggttatgaaa gaatgcttga agatcccgaa
    43501 ttggaacaat tgacgtttac ttatctaaac gaagaaacgc agctaactcg tgatgagcat
    43561 cagcgcattc atttcacaac aagagatctg cctagtaaat aaaaaataag ataaaggtca
    43621 tcggattcga ttctgtccta tcagatggaa agactagttg atcgaaaaaa aggctgtacc
    43681 aaattttggt gcagcctgtt ttatggagca ttgcccgctc ttttttataa caatttttta
    43741 cagaaaatgg tactattgaa gtattaataa gtgaaaaaca gatgagtaag aggaggcaag
    43801 tagtatgaaa gagccagata caaatgcaaa ttatgagcca gacgaactag aggagacgaa
    43861 tgcggatcag gatacaggac aagaatcgtc ttctttttac gatatcaaag aaaaagcaag
    43921 catgaatctt tcccaattat tagaagactt acaggctttt gaaaaagctg tccgcgaaga
    43981 agatatccct gagatctacc gtttatacaa tggccgattg aatgaagaat taaaaagaag
    44041 ctcaaatgaa aatcacgaga tcgatcaatt gctgatgcgt aagatccatg atcgtttttt
    44101 acaggaattt ccttttatgg aacaagtaga aaacatctcg ccaacgatga gctattacaa
    44161 aatcggcact tattaccatg atcggcccac ggtcggtatt gatgcaagtc tgccagaaat
    44221 ttttgttttg cctaagatcg atgaagagtg ggagaaatat tcccaaccgg agtcaacgga
    44281 ctatgacaaa aaaatcaatg agctagacgc aaaggtgatc actgctcaga cagaaattga
    44341 acgtttagat gaacaaataa aagaaatcaa tcgacaaatg actgatttga acgacaataa
    44401 aggattcttg aatcgtaaaa aaatcgagga agaaattcaa gaattagaga agaagaagca
    44461 agtactatct aatgaaaaat taggctggct tccttatatt gagacgcctg aaacaatcca
    44521 gcagcaaaaa gaagcattga agcaagaagc aagagcagac cagcttcgtg cagccatcgt
    44581 agaaaaagaa caaaggcaaa tcagacgcta tttcggtagc aaagagggat tcggtcaagc
    44641 aatccatgaa ttcttgatga attatcttgg caatgagaat cctaataatc aatctaatga
    44701 aggaggttcc gagtatgaat gaacacgatg aagcagaatg gacaaaaaat gaagaacaaa
    44761 cagaagatca tgaagaaacg aacacttcat tggaagaaca aacaagtaat cctctggatg
    44821 acacagaaga aatccctatg ctagaggaaa caaaaataca cgaaaaagaa aaagtaactc
    44881 cgacgaatac gaatactgca gaaaacaccc atgcttacga aataactgaa aatcccgggt
    44941 atttagaagg aaaagagcaa gatcatcaag atatcgtcag tttgattgaa acagcggaag
    45001 cagaattagc ggatttacgt atgagaaaag atttgatcga atcagatttt ccacaattat
    45061 tagaatcata tgatcgtttt atattgaatg aagaaccaat ctccacgatc ggaaagacaa
    45121 gcctgatcga atacttcacg tatgaattac tgaaaccgtt gaatgatatt ggtctggaac
    45181 ggtcaaattc agcttatgac acatggaaaa caagacattt ttcgatcaat tatacgttga
    45241 atggacaaaa cgaattagtc ttttcctttg tattaccgac catcgatcaa cgataccaag
    45301 tggaatcgat gagtctccta aacgtatcac cagagacaat ggaaatcaat gtccaagatg
    45361 accgggtgct ttctttgatc cgacactggt cagtggatcg agtattctct gcagggcaga
    45421 tcacgatatt caatcacaaa ttgaatcaat tattagccca tgcaagaaca cttggtttta
    45481 ccgttaatca gacattacta gacaatacga agccacttcg tttgaatctt cagagcgaat
    45541 ttgaattgac gaatgaagta ttggatgata tttttatcgt ggcaatgaaa aatccatcct
    45601 acgatatgga aaagatcaac gaaactactt atcaagtacg attagataaa ggacagtctt
    45661 taacgataac aacaaacgaa aaagatcaaa cagtcttgtc gatctcatct ggagactacc
    45721 cacgatctgt cattgatttc tttatcaatt acgaattctt ggtcccatta atggtgagaa
    45781 agtcctgatt ggataagttg gattaccaga tgtcattcag ataattctgt tccaaaggac
    45841 ttgcggcagt tatccagaat aattgtcaca agtcttttct gtatgtacta aatggacgtg
    45901 aataacttgc tgatgaagga gggatttcat taggaatgtc cacaaataaa atagcacagc
    45961 ttagcttatt gtctgctgct tgtgtagcag gtaggatcgc ttttcaattt attccgaatt
    46021 tccagccaat gactgctatt tttttattta tagtacttta cttaagctta aaagatgcgt
    46081 taattgtcat gagtctttct attgcgatca gcagttttta ttttggtgtt ggaccatggg
    46141 tcatcggcca atggatcagc tatactgttg ttctgagttt gttttcaatc gtctgcttga
    46201 gaaaaacagt gcaaaggaat ctatggttaa agggagtctg tttttttctg gcgggcatgg
    46261 tttacggaat aggtatgacc gtttttgata cgctgttata tcgtttgcct caaccttgga
    46321 tctattacct tcaaggggtg tcgtttgatt tgatgcacag tataggcaat gttgtgttct
    46381 ttcttgtttt tctgccagtc gtcaaacgtt tttacaatca ttcaggagga aaaaatgaaa
    46441 aaaataattt atagtttgct tgcaatgagt gtcagtatac tcattttgac aagttgcagt
    46501 acaacctata cacaatcggc ttccaaccaa aaggaggaag taaaaacatc gcaaaaagca
    46561 acaatcacgt tacaagaaaa tggtcaaaac ttttcggaaa aagaagtgtt cttcaaaaaa
    46621 ggcgatgatt tactgagtat tttgaaacga aattttgaag tcaaagaaga taacggcttc
    46681 atcacttcgc ttgaagggca ctcacaggat gagaaaaatc aactctattg gatgtttact
    46741 gtggacggga aaagtgctac tactggtgcc aaagagatca aattgaatga tggacaatcg
    46801 gtcattttca atttgtctaa actataagtt tcataaaaaa ctgttaaagg gcgaatattg
    46861 ccataattca gtgagttcag ttgatgaaag aaggaaaata acatggaaaa ttttaaaaaa
    46921 agcggaatgt tttccgtaat tgctgctcta ggggctaata ttctagttgc tatcagcaaa
    46981 tttgtcggct atgcaatcag tggcagtgcc gccatgctaa acgaaagcat ccacagtatc
    47041 gttgattgca gcaatcagat tttgctgtta ttcggtgata aacaagccaa taaaggacag
    47101 agcgagttgc atcaatttgg tgaaggacga gcaaaatact ttttcagtac aatcgtcgca
    47161 atgatgcttt tcttcggcgg tggggcactt ggggtgatgg aagcttttga aaagttgacg
    47221 catccatccc atgaagtggg taatccgatc attgttatag caatactgtt atttggtttg
    47281 gtaatcgaag gaagttcgtt acgcgtggca atgaaagaaa tcaaagaatt gaatactgaa
    47341 aaactttcca cgatgcgctt tttgcgcgaa agtcgacaca gtgaaatact gattattttt
    47401 acggaagact tgtgtgctgt aatcggtttg gtcttggctt tagcaggaac aatattgact
    47461 tatgcaaccg ggattgctgc atttgatgcg atcagcggat tgctgatcgg tttcttgctg
    47521 atgggagccg ccattttcct agcaaaagaa ttttatagtc tgatcatcgg tgaaagcgtg
    47581 acagcaagcg atttatcaaa aatcaagtta gcttttgaac gtcctgagat cagtcggctg
    47641 atcgatataa aaacagttca tttaagtcca acggagattt tagttgcagc aaaagcagat
    47701 atcgttggta acaaagagaa tgaagcttac tcggtcatca atgatattga aaaaaatatg
    47761 cgtcagtctc ttcctgacaa gaagatgtat atatacattg aaacagataa atatgaccca
    47821 aattattctc gtaaataaaa cgtttattca tgaattgaag caaaaatgag aaaaatataa
    47881 tcttgttttt aaataaaacg gctacaattt agcgaattta tgttacaatg agtccgctgt
    47941 ttatttgttg taattaaagg agatatttta atgaacaaaa agaaaagtgc gccatggctt
    48001 caagctttgc atgcagtgat gccactttgt ataagctata taccagtagg attagcttgc
    48061 ggagtattgt tgcaaaaagt tggatttgat cctctcttat caggactgtt atcgattctg
    48121 gtcttttccg gtggcgcgca gtttttagtt gcatctatgc ttacgacgca agcatcattt
    48181 gcaacgacat tattgatggt tttcttttta gaattacgct atacattatt aggagcaagt
    48241 cttgccggtt ttatgaaaaa agaaaagcgg acgtttttgg ctgtcttttc tcaatcactg
    48301 aatgatgaaa actatgcggt gaactactta aagttttcaa ctgacccttc ctggaataaa
    48361 agaaaggctt tatatgtcaa ttggttctca atgactgcat gggccggtaa caatatgatc
    48421 ggtaattttt tcggctcggt gattcgagta gatgctgacc ttgtccattt tgctttgacg
    48481 gccatgttca ttttcatgtt tatcatgcag atgaaaagcg cactactgat ctttacaggt
    48541 ttattctcag gcgtattagg ggtcgtattc atggtattat tccaaaatac tttcggattg
    48601 attgcagcaa cagtcattgc ttcatttgcc ggatttatgc tggagaaggc attcaaaaaa
    48661 gaaaaagcta agaaactaag agaccgcggt aaagatgtca atgagccgct cttcaacttc
    48721 ccggaacagg aggccaatca ccatgactaa actatatttg ctacttttag ttgcttgtct
    48781 gttcatcgtg gcatatatcc cgcgcttgtt cccgatgctt tattttactc atcgaaaagt
    48841 gccatcctgg ttcagtgact ggatgaaata tgtaccggtg gcattatttg cggcgttagc
    48901 ttttaaagat gttttcatta ctcatgaaca tctggatatt gcttggaata tcaaaatagc
    48961 tgcaatgatt ctagtagcag gcgtggctta caaaacacgt tcgatggcgt tgtcagtttt
    49021 gacaggactt gcgtctgtct ttttgctgtc tatgctttaa actgttttat tttattaaaa
    49081 acagagattg cgacataagt tgttcaaact gatctatccg aactgcattt gcaacagtca
    49141 attctggatg caagtttatt cgtagggata aaaaagatta gtgttggctt atgatgcaag
    49201 ctctttttta ttttaggaat tagagaggga tttgtccttc tatgattttt tgctataata
    49261 gggaagatgt ttattttatg aaagaatagt tgagggaatt taaatgaata aaaaattgat
    49321 gcaaggaaca ttttggctaa cctttgctaa tcttctatgt aaagttttag gggtagtcta
    49381 tttgattccc tggctaagta tgatggggaa caatcaagat ggtatgcttg ctacgacatt
    49441 gtataatgtt ggctatcttc cttatggatt gttcctgatg cttggtacag tcggatttcc
    49501 aaatgcgatt gcaaaaaaag tagctgtagc cacaaaagaa ggagataacg ctgcttgtcg
    49561 gctgattttt agaagtacga tcaatatcat gtttgtcatc ggtatcgcct ctgctgcact
    49621 gatgtattta tttgctcctt tactagccgg aatcagtccg attgctaacg ttaataatgg
    49681 gatactagct atcagaagtt tatgcccatc tttgattgct atcccaattc ttagtgcaat
    49741 gagaggatat ttccaaggaa aaaatgatct gcggccttat ggaacttctt tgattatcga
    49801 acaggctgtg cgagtgatcg ttatcttggc tggtacttat tacttgcgcg tattgactga
    49861 cggaaccata ttagaagctg tattgatcag tacagtcgct tctttcttcg gtgggttagc
    49921 tgcgattatc catatgtata tcgtcggacg cagaaaagac ttcttcgaac ttaaagattt
    49981 tttgatttcc agccgttatt tcgaaagaga aaaccgatct gcctctgtct ctatcattcg
    50041 ggaaacacta ccgtttattt ttgtcggctc agtcattact atcgttcaaa tgatcgacca
    50101 agtaacgatg aaaccactgc ttcacttttt ccgtccagag atcgcagatc agcaactgga
    50161 attcttattc agccgtgctt ctgtcaatcc aaataaattg acattgatcc tgatctccat
    50221 ggtaggaaca gtagctataa gcagcttgcc aatattaagc acgatgaaga aaaaagatcg
    50281 gatacaaatc gaaaaaacag taggagatag tttttcgatt gcgttattga ttcttcttcc
    50341 ttcattgact ggaatgtctt tattagctgg accactatac acattgtttt ttggctatga
    50401 tcctgaaagt gtcggatatt tccaaatggc tttgctagct tctttgtttt tctctttatt
    50461 cacgatccta tctacgatgc ttcaatcttt gaatcaccat cgttttgcga tccgattaac
    50521 tgtagaagca attatcctga aagtcatctt ccaagtaatc ggattaggat tagttggcgg
    50581 atacgggatg agcttatcaa atggcttagc attcggtatt gtctttgttc gcggctatca
    50641 ctttatgtgc aaagaatacc gaatagcacc tttagcaaag atcagcaatt ttttcttaaa
    50701 aactttccgc tccaccctga ttatgcttgc agtatgtttt gccgttttct ttttgctgaa
    50761 tcagcgattg tcaatggaat caaaaagcta tgcaatgatt tattgtgtgg ctgtaggaag
    50821 tattggcggc ttagtatttt tattttctca attcggaaaa aatgggtttc gaatgttgaa
    50881 aaatgttaaa catcatagca gaagcaaaga ataggttaac taatcgtttt ttgctgtcac
    50941 ttgaaaaacg gcaactcgta tgattacgct tgtcgttttt ctattttcca attttagttt
    51001 catatctaat cttacttatg atatagttat aaggtctgga aaaattcttt gaaacgagga
    51061 aattaaacac atgaaacttg cagtagttac agatagttcg gcatatctgc cggaacgtat
    51121 caagaaccat cccgacttat tcgttattcc aatccctttg attatggatg ggaaaattta
    51181 taacgaagga atcgatatcg aagcggatga atattatgga cttttaaaaa acagtaaaga
    51241 ttttcctact acttcacaac ctgtcgtagg ggaagttttg ggtttatatg aggaattgaa
    51301 agagaaaggg tatgacacga ttttaagtat ccatctttct tcagggattt ctggctttgt
    51361 caacacatta tttgcgatga aagatgacat cagcggagta acggtcattc cttatgactc
    51421 taagatcact agtatgccga tgggacacat ggtagaagct gccttagact taaatgatga
    51481 aggtcagtcc cttgatgaaa tacttgcaca tatcgatcga atccgagata atacctatgc
    51541 ttatctgatt gtagatgatt tgaacaattt agtacgagga ggacgtttga caaatggtgc
    51601 agcgctgatt ggcagcttat taaaaatcaa accgatcctg acattttctg aagggaaaat
    51661 tgttttattc gaaaaaatcc gttcaagtaa aaaagcattt gctcgagctg aagaaattat
    51721 tggtagaaga aataacgaaa tacaaccgcc agtcaaactt tacgtgatac atgcaaataa
    51781 tttagaagta gcgattgcgg agaaagagaa attgcagaaa aaatatccaa atgcagaaat
    51841 cgaaattggt catttcggac cagtcattgg tacacattta ggtgaaaaag ccatcggcat
    51901 tgccatttca gcgcaataat tccttttatt caaaaaacat accaaaaata t
//
LOCUS       DAZKKZ010000014        51519 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.014, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000014 DAZKKZ010000000
VERSION     DAZKKZ010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 51519)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51519)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51519
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.014"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            207..1208
                     /locus_tag="ACG8LA_000865"
     CDS             207..1208
                     /locus_tag="ACG8LA_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HFQ0203181.1"
                     /translation="MTSTVFIILLGFVCRKKGIFSESVGKILSKVVLTVALPALAFRA
                     FMQDINTELLMQGINVLIWGLVIYIILILVSKPFFLSYKGDKQTTLRVLTIFGSTTFF
                     GTPIVSAIYGPVGVMYSSIFNIGYRIFLYSYGYIKMSGLKMEAKNIKAMFVNPIIIAT
                     FAGLFIWLFQGYLPQVSVTGAEGEISQVAFLRIDQTAPWLFQPMDYLAGLSSPLAWLA
                     IGATLGEVSFKKAASEKTSWYYSLVKVVFVPALNIVILAVLTATNILPVNFEALATIV
                     IMMATPAATVAAAYAISFDREALLASNASLLSTIFAVVLTPVWIVVLQMIHGIGLFS"
     gene            1227..2246
                     /locus_tag="ACG8LA_000866"
     CDS             1227..2246
                     /locus_tag="ACG8LA_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyacid dehydrogenase"
                     /protein_id="HFQ0203182.1"
                     /translation="MRIACYGVRPNEIDFFEKLNIYHYDLSLYEELLTHDNIVSAKDH
                     DAVLLRGNCIADETNLAKMQEYGIRYVFTRTVGVNHIDLQAAADFGMTVARVPSYSPN
                     AIAELSLTFAMMLLRNTAYTTIRTSFKDFRVDEQMFSREIRNCTVGIIGTGRIGLTEA
                     VLFKGLGAKVIGYDIHQTEAAKKVLTFHSLEELLAKSDIVSIHVPHIPGENDQMINEG
                     FLAQMKKGSILINTARGELQDNEAILRALKSNHLAGFATDVFANETEVFFRSFKPWET
                     IPDPAIQQLVEMYPRVLVTPHVGSNTDEALSNMISTSFENFREIIETGKTKNEVSLPK
                     ARQLR"
     gene            complement(2348..3064)
                     /locus_tag="ACG8LA_000867"
     CDS             complement(2348..3064)
                     /locus_tag="ACG8LA_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFQ0203183.1"
                     /translation="MMTNVLIIEDDPMVAELNRTFVESIPNMNVIESFRNVEEGKKYF
                     RQKNADLLLLDVYMPGESGIHFLSWLRQQGNDIPVILITAADDIETIKNVIRYGALDY
                     LIKPFTLQRFQLAIEKYLAFSQTIQTTEKADQKLIDQVFNHTTPIHEIPSFIDLPKGL
                     SKLTLKKISAFILKEDTIFSTKELAQKSSLSRISVKKYLNFLVEQDILNERIKYLEIG
                     RPLTCYELTKNGRKKLTDYC"
     gene            complement(3033..3818)
                     /locus_tag="ACG8LA_000868"
     CDS             complement(3033..3818)
                     /locus_tag="ACG8LA_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFQ0203184.1"
                     /translation="MYLNGIETISSVTPLFSNDRFLGAVATLRNRSEVMKLMEELGGT
                     KQYINSMRAQTHEFMNKLHVISGLIDLKKYEEVTHFIQQLNQNYKKEIGQVSSLIKVP
                     AIAGFLLGKINEAKEQSVEMLLESDSFIPKMEMDDSIHSLLQVLGNLLDNAKEAVLQK
                     HERNGQVRIHLNYDTEAEVFIVTVCDDGVGISEEISEKIFTLGFSTKGINRGFGLNLI
                     HSIVKRHGGFLEFSKQTNGGTIVYLELPKKEDQNDDKCPDNRR"
     gene            complement(3809..4558)
                     /locus_tag="ACG8LA_000869"
     CDS             complement(3809..4558)
                     /locus_tag="ACG8LA_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HFQ0203185.1"
                     /translation="MNRSSVSDKISSIAKIVANDKLIQKKLQTGDPTHAIQGITNEIM
                     IASNLDFIVVMDPEGIRYSHADPSYIGLPFSSHEDVKKVIGGQEFFSEKEGMLGFGFR
                     YFVPIYYDQEIIGAVCVGLTNNTIDNQVKDGQKMIVFSLIIGLSVGIIGAVFLAQKMK
                     KVLLGLEPQEIAEQLSEKTIIENEVDEGILAISSDKTILLINTPAKNIFYQTEQLLDF
                     EVGKKSVIIYMTFCLKRRLSIKRPFGLNPCI"
     gene            4856..5380
                     /locus_tag="ACG8LA_000870"
     CDS             4856..5380
                     /locus_tag="ACG8LA_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NfeD family protein"
                     /protein_id="HFQ0203186.1"
                     /translation="MIGGIALETIYWYTLLICAGLAVLLIIFGDVFDFDGPLDPMLII
                     PWLTFTSLFGFLGERLTDQSSLFLFIASGGISIVLVFLLNFYILMPMKHAESTMSSSE
                     KTLEGQVAVVITPIPVRGMGEIQLKSVTGSISRPACFYSPQEQTAERGTKVLIIEIKE
                     RICYVMPYESMIKA"
     gene            5396..6895
                     /locus_tag="ACG8LA_000871"
     CDS             5396..6895
                     /locus_tag="ACG8LA_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flotillin family protein"
                     /protein_id="HFQ0203187.1"
                     /translation="MEIPVVFIAIAIAALILLMLLIVFVAKYQTAKPDEALIISGSYL
                     GSKNVHIDESNNKIKIVRGGGAFVLPVFQRSNRISLLSSKLDVSTPEVYTEQGVPVMC
                     DGTSIIKIGSSVEEIATAAEQFLGKTREELENEAREVLEGHLRSILGSMTVEEIYQNR
                     DKFSQSVQEVASVDLAKMGLIIVSFTIKEVRDKNGYLDSLGKPRIAQVKRDADIAEAE
                     ALKETRIKKAQAEKESQAAELQRQTEIAESLKEKELKLATYKQEQDVAKAKADQAYNL
                     ESARAQQQVIEQEMQIKIVERQKQIELEEKEITRREKQYDSEVKKKADADRYAKEQEA
                     QAQKVKEVTEAEAERFRVEALAEAEANKTRLAGQAEAEAALAKGKAEAEAKQKIANAF
                     KEYGEAAVLSMVIDMLPQLMREAAQPLGNIEKISVVDTGSSSGETSGANRVTNYATNL
                     LSSTQETLKATTGLDLKEIVENLSTRGTTSQVNMYEAPKEAEQNSMKEE"
     gene            complement(6983..7585)
                     /locus_tag="ACG8LA_000872"
     CDS             complement(6983..7585)
                     /locus_tag="ACG8LA_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HFQ0203188.1"
                     /translation="MQFGRFRLGMRTIKSALAVFLCILFFHLTQRGIPMIAALSAVFS
                     LRQDLTTTVSFGKSRIIGNTLGGTLAIIYFFVKSYFHNDFLVELILLPILVIIVIVVS
                     DGINNNSGIISAIATLLLIALSIPQGESALYAIQRVLDTFIGTFIAIGINFFLRPPET
                     EKKEELSEDLVELQKKERLLRTNLQEIEAKIQKQKKNSED"
     gene            7689..8645
                     /locus_tag="ACG8LA_000873"
     CDS             7689..8645
                     /locus_tag="ACG8LA_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HFQ0203189.1"
                     /translation="MRIGMRTVKTVISVFFSMVTAGSLSLLYWPAAGIIALLSVGNTK
                     RSTLRTGMNRIAAFILATATALFSFFAVGYTIFGFSLFLFLFIPLASRFKLTEGIVVN
                     SVLVTHYLVEENMSWQLIGNEAGLMAIGLVFALLANVYMPDRTKQLKENQIQIEKEFR
                     NILRQMAEFLLSENKEDVQIKCEHLLTFIRESQEDAREHQENYWLRQPLYYETYFSMR
                     RAQANVIKDMLENLERIQQPAYYGKHIYGLLIYTAETFSESNDGRQILTRIEEVYVLY
                     RQMPLPTSRPEFEDRAELFQFLQSFKSFIEIKAEFSQQKIQK"
     gene            complement(8950..9906)
                     /locus_tag="ACG8LA_000874"
     CDS             complement(8950..9906)
                     /locus_tag="ACG8LA_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFQ0203190.1"
                     /translation="MKKYQWGIVGLGTIAHEFAESFNQETSELTAVASRTSEKAENFA
                     HRYNIPKAYGSYQEMLDDAEIDIVYIAVPNRQHIDHILAALEAGKHVLCEKAITMNKK
                     ELADAMRLAEEKNLILAEAMTIFNMPLYQQLRSIMDTGKLGALKMIQAPFGSYKEPDP
                     KNRFFNPELAGGALLDIGTYAVSFARFFLSSQPEVVASTMVPFETGVDEQSVTILRNK
                     ENELAAVSLTFQAKMPKVGIVAFENGYVTIADYPRADRAEILFTDGTKEFIESGNTSE
                     AMNYEIKNMVHMIEGDLPNRSLFLTKDVIEILDQMQVLWKNM"
     gene            10080..10640
                     /locus_tag="ACG8LA_000875"
     CDS             10080..10640
                     /locus_tag="ACG8LA_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0203191.1"
                     /translation="MHQVYIDLIMSVLLEQFETEKNFLDEYLLISPEQWQKWKDGEKN
                     LPSEAMQKVKNLFTDYEWMLTQKILRQTIIFPEKRNVAVAEYKQIKTRIAQKWLSSKA
                     AKVELIPLKNNQQAGRYLDLKVSIQYDEWGYDDILNFRLPADVQKQIEGEKIELLDWV
                     NENLEETYVHEANGEREEQRKDFSSE"
     gene            10633..11457
                     /locus_tag="ACG8LA_000876"
     CDS             10633..11457
                     /locus_tag="ACG8LA_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase family
                     protein"
                     /protein_id="HFQ0203192.1"
                     /translation="MNKFLGFGAVVIMIAAMGYVIFSDDDSHVQAGNQAVERTSTKTT
                     ASKEKNSQTTSSKVKDKETKDRTSKQLPDVKTDDWKLVLVGPDHKLEKEIDESTQLAS
                     LSNGYLIDKRIAPEYEAFAKAAEAAGFPLVMVSAYRSVSSQQQVFEQNVQDVMSRQGV
                     SEEEATKITKETITEPGYSEHHTGLAVDVVDQNWYNSYPSTVLDASYGDQPGAKWIAD
                     NAAQYGFIVRYPKGHEDITKITYEPWHLRYVGKENAEYITKHQLTLEEYLNELNEK"
     gene            11467..12084
                     /locus_tag="ACG8LA_000877"
     CDS             11467..12084
                     /locus_tag="ACG8LA_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HFQ0203193.1"
                     /translation="MAKKKWKKQKRKNIRWPAVVAGVAVILLAFVFSLKNLSSPFTDN
                     QQENEAQSHQQFIERLVPHAQELQDGYGVLPSIILGQAILESNWGKSTLASKYNNLFG
                     IKAYGDQKKVSLETKEFVNEEWITIQGDFKVYDSWEQSMDDHTQLFVQGVDWNPALYE
                     KVITATNYQEAAQALQDAGYATDPGYAQKIIQVIETYQLNQYDRR"
     gene            12102..12785
                     /locus_tag="ACG8LA_000878"
     CDS             12102..12785
                     /locus_tag="ACG8LA_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HFQ0203194.1"
                     /translation="MAEQFTPEIMTELRKDIVRVPEIILEASGIKIFGKLIRSIIFTT
                     DIAIIRNTNANAVIAVYPFTPHPAITKSIIEAADIPVFSGVGGGLTQGARSSYMSMFA
                     EAQGSLGVVLNGPTPLETVKEVCRVVDIPVISTVTSKYTEIDEKLAAGISIINISAGK
                     ETAEAVRHFRKKYPELPIIATGGPTEESIAETIQAGANAITYTPPSSGELFSRKMEKY
                     RETEKKNHE"
     gene            13468..14751
                     /locus_tag="ACG8LA_000879"
     CDS             13468..14751
                     /locus_tag="ACG8LA_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFQ0203195.1"
                     /translation="MKKRMRIILALSVMLFFLTACGQEDDKKITLNMAWWGSQVRHDA
                     TVKVIELYEEKNPHVTIDYEFYDYEGYYTKLGTLAASDDIWDIFQLNNQFPQYINQIE
                     PLDEYVEQGIIDISNADESYLATTTYDGQLVGLSNGVNSFAIAYNKNIFEQLNIPEPA
                     SNWTWDEFEQISYQITEELGIYAISRFEDFIAGCIIQIPQVEKGLNFYNREDLSNSLG
                     FENPDYLTDFFQLRKNLVDKGAHPEPGGGAASTTDLSFQAVRDREAAMVFLSSNQLTE
                     ILSGAPEDMEIQLINPPRRKADGESGIPLRSSQMLSMAKSSAHKEEAAKFIDFFQNSE
                     EANEILKGERGVPIMSNIREQLARADDATLQATFDYLEMISDMDNGEVNVFDSALNPE
                     IQDQYNLLVEKVIYEEVTAEEAAESLYEFASNILG"
     gene            14767..15654
                     /locus_tag="ACG8LA_000880"
     CDS             14767..15654
                     /locus_tag="ACG8LA_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFQ0203196.1"
                     /translation="MKKEKLKRFLDQDNVVGYVFASPFILGFLLITVIPMILSLYYSF
                     TDYRLGNPVSWIGLDNYIKMLSDARFLNSIRVTFLYVFASVPVKLIFGLLIAYLLTRN
                     IKGTTFFRSLYYVPSLIGGSISIALVWRELFSKNGLVNIFLERLGAPALSWFSDQKLV
                     MIPLVLMSAWQFGSAMIIFAAGIKEIPGSYYEAAEIDGANKWQTFYKITLPLLSPIIL
                     YNLVMQTIAAFMTFTQAFIITQGGPNDATNFYALYVYNQAFSFNSMGYASAISWIMLL
                     IMGAVTFLIFKSSKKWVVV"
     gene            15671..16507
                     /locus_tag="ACG8LA_000881"
     CDS             15671..16507
                     /locus_tag="ACG8LA_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFQ0203197.1"
                     /translation="MNNTVTKWFQYGFILLLGLVMIYPVLWMIAGSFKTDQEIMSGSL
                     NLIPETFQWENYAKGWAGFAGISFFTFFRNSFVISAVSTIGTVLSSTCIAYALSRIDF
                     KGKRFWFVVMLVTMMIPAQVILIPQFIIYNRLNLVGTYVPLILPHFFGQAFFIYQIMQ
                     FMVSIPKELDESAIIDGCSKYSVFTKIIFPLLKPSIITTIIIQFYWKWDDFMGPLIYL
                     NKPRSYTVSIAIKLFADAGSSTTYASMFAMSTLSLLPVFLIFLFFNKYLVQGISTSGL
                     KG"
     gene            16510..17133
                     /locus_tag="ACG8LA_000882"
     CDS             16510..17133
                     /locus_tag="ACG8LA_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0203198.1"
                     /translation="MKKPIEEMFLYKLNYYVCRIFLTSLISNALFALVLGCLFTLGLV
                     LSARVVYLIYFLMMYPSYYLSVHYLAEKKVCWRKGKIKRMCFIITLFQLFVIIFAVDW
                     YLLVGKIGAWYLIPFLLCLLLFVSHSFFSTLIDICKEDKADSLVYLIKRNIWLLSKNV
                     KGFLWYLCLLYGLFWCIQHDFLLTALLYPGLPFVTVFCLKEKENDFK"
     gene            17130..18422
                     /locus_tag="ACG8LA_000883"
     CDS             17130..18422
                     /locus_tag="ACG8LA_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFQ0203199.1"
                     /translation="MKKKYVQVGLGGRARFFYEAIASTYHQTCELVGFCDVSQTRMDY
                     ANRILVNKYGQKKVKTCMPSQFEQLLDDVRPAEVIITSVDRTHHDYIIRAMKKGYDVI
                     CEKPLTIDEEKAQEIITVQKQTGRSLRVTFNYRYAPYHTKIKELIESDVIGDVFSIHF
                     EWLLNTQHGADYFRRWHRNKHNSGGLLVHKSTHHFDLVNFWLNSRPQKVFAFGGLNFY
                     GMHNAEKRGVEIFYSRCYGSELAKADPFAIDLSANEELREMYLEAEKDSGYIRDRSVF
                     SDDISIEDTLGVTVKYETGAILTYSLNAYMPWEGFNVSFNGSKGRIEMKVIEKSYINA
                     GGDKKDEGAAVLQSIHVYPMFGEPYEVIVEQEAGGHGGGDPRLLDDLFGEEKEEDPWN
                     RAATHVDGILSILTGIAANHSIASGKAVVIDELVSLKE"
     regulatory      18781..18878
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            18994..19575
                     /locus_tag="ACG8LA_000884"
     CDS             18994..19575
                     /locus_tag="ACG8LA_000884"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016763 - pentosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0043101 - purine-containing compound
                     salvage [Evidence IEA];
                     GO_process: GO:0046110 - xanthine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HFQ0203200.1"
                     /translation="MKELVERIQKDGRILGEGVLKVDSFVTHQVDPVLMEQMGKRFAE
                     VFKEQGITKVVTIEASGIAPALFAARELDVPMIFARKAKSLTMDEELLTASVYSFTKQ
                     VTSTISISRKFLSSEDKVLIIDDFLANGQAAKGLIELCQQAGAQVEGIGIVIEKSFQD
                     GRQLLEEMGLRVVSLARIASLTNGQVEFLEEDA"
     gene            19578..20885
                     /locus_tag="ACG8LA_000885"
     CDS             19578..20885
                     /locus_tag="ACG8LA_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleobase:cation symporter-2 family protein"
                     /protein_id="HFQ0203201.1"
                     /translation="MEKETQNGKAAVLGLQHLLAMYAGAVAVPLLIGTGLGFNQEQMT
                     YLISIDIFMCGLATLLQLTVNRFFGIGLPVVLGCAIQAVAPLILIGTNEGVGAIYGSI
                     IASGIFVVLVSGVFSKIKKLFPPIVTGTVITVIGLTLIPVAIEKMGGGNATAADFGDK
                     TNLLLAFVTILLIVGVQMLAKGFIRSIAVLIGLVGGSILAAFMGMIDLSAIGDAPLFH
                     VPQPFYFGKPTFDVWSILLMIIISMVSMVESTGVYFALGDITGKNVGEEELKKGYRAE
                     GLAVILGGIFNTFPYTGFSQNVGLVQLSGIKTRKPIYFSAFFLIVLGLFPKIGALAQI
                     IPEPVLGGGMLVMFGMVAVQGIRMLLEVDFSNDKNLLIVAVSVGFGLGFNVTPTLFSQ
                     MPQTLQMFTGNGIVMSSITAIILNLIFNGLKKDEEILEEAFKK"
     gene            21301..21789
                     /gene="purE"
                     /locus_tag="ACG8LA_000886"
     CDS             21301..21789
                     /gene="purE"
                     /locus_tag="ACG8LA_000886"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009320 - phosphoribosylaminoimidazole
                     carboxylase complex [Evidence IEA];
                     GO_function: GO:0004638 - phosphoribosylaminoimidazole
                     carboxylase activity [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HFQ0203202.1"
                     /translation="MTAKISVIMGSTSDWETMKEACQILDEFGVSYEKKVVSAHRTPD
                     LMFEYAQNARKKGIKIIIAGAGGAAHLPGMVASKTTLPVIGVPVQSRTLNGLDSLLSI
                     VQMPGGVPVATTAIGKAGAINAGLLAIQMLSMYDLELEAKLAERRSMLAKTVIESSDQ
                     LG"
     gene            21782..22906
                     /gene="purK"
                     /locus_tag="ACG8LA_000887"
     CDS             21782..22906
                     /gene="purK"
                     /locus_tag="ACG8LA_000887"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004638 - phosphoribosylaminoimidazole
                     carboxylase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HFQ0203203.1"
                     /translation="MVKPLLPGSTIGIVGGGQLGRMMAISAKEMGFKVGVLDPVSDCP
                     AAQVADWHIESVYDDTFALKELARRTDVITYEFENVSVEALNAILPMSFIPQGTDLLA
                     ITQDRLLEKSFLETNNIVIAPYATIVSPTDIQDAIDGIGYPCVLKTTRGGYDGKGQYV
                     LKSRADLAPAMDLLREGTCVLEAWIPFEKEISIMVAGNGQGDFTTFPVVENIHHNNIL
                     HETIAPAAIDQDVIEEAERIARVIAEAVSLSGVLGVEMFLTKTGGLYVNELAPRPHNS
                     GHYSIEACSMSQFDAHIRGICGWPLGEKVRLISNAVMVNVLGEQLLESYRLIENKPDW
                     QFHFYGKKQAKKGRKMGHITILTEDIQQTLEEIKQTNIWD"
     gene            22919..24214
                     /gene="purB"
                     /locus_tag="ACG8LA_000888"
     CDS             22919..24214
                     /gene="purB"
                     /locus_tag="ACG8LA_000888"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004018 - N6-(1,2-dicarboxyethyl)AMP
                     AMP-lyase (fumarate-forming) activity [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HFQ0203204.1"
                     /translation="MLERYTRPEMGNIWTEENKYRAWLEVEILADEAWAELGEIPQED
                     VKKIREHASFDIDRILEIEKLTRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLIKQANDILREDLKRFTEIIGEKAKEHKYTVMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAKGVEAGKISGAVGTFANIPPFIEEYVCKQLGIRPQEISTQVLPRDL
                     HAEYFSAMALIATSIERFATEIRGLQKSETREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MAGLARVVRGHMVTAYENVTLWHERDISHSSAERIILPDTTILLNYMLNRFGNIVKNL
                     TVFPENMKRNMSATFGLIYSQRVMLKLIDKGMTREEAYDLVQPKTAYAWDNQVQFRPL
                     LEEDPTITSVLSKEEIDDAFDYHHHLKNVDVIFKRVGLE"
     gene            complement(24336..25724)
                     /gene="ltrA"
                     /locus_tag="ACG8LA_000889"
     CDS             complement(24336..25724)
                     /gene="ltrA"
                     /locus_tag="ACG8LA_000889"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003964 - RNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0000373 - Group II intron splicing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HFQ0203205.1"
                     /translation="MRRPQKTRKLGYHQRASVEHEGYDEVRSTSCGEQRKQDGVENLF
                     GRILDRNNLNQAYLQVVRNKGAAGADGMTVDQLLPYLKEHREELLSNLRQGNYKPQPV
                     LRVEIPKPNGGVRKLGIPTVIDRMLQQAINQVLQPLFEPEFSDNSYGFRPNRSAHDAV
                     KKAKSYYEQGYRYVVDIDMKAYFDTVNHDKLMYFIERKVKDKQVLKLIRQYLMSGVME
                     NGLITTTEEGTPQGGNLSPLLSNIYLNEFDQVLENLGHKFVRYADDCNIYVRSKRAGQ
                     RVMKKSIQFLEEQLKLTVNREKSAVGSPLKRKFLGFCILPTKKGIKIRPHAKAKQRVK
                     SKLKQLTKRNRGRSIQLILKEIKQLMTGWINYYGIGEMKEFMRELNGWLKRRIRQYIW
                     KQWKNPRTKRKNLIRLGIDKAKAYEWSNTRKGIWSVSKSHILHRSLTDKELARQGYED
                     ISLKYQFVHSTY"
     gene            complement(26293..26670)
                     /locus_tag="ACG8LA_000890"
     CDS             complement(26293..26670)
                     /locus_tag="ACG8LA_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0203206.1"
                     /translation="MEDAIKQGQLFLSELTAEERSCLYNDLLSIKDVYLCNKDTSFYT
                     FRKIRRATKRCAECRKRTFLYQTEHKGELSISQIHEQKRFKNHYRIQILFNGQEMEYA
                     FLENLLQHLHNQHFSYNSQAIYA"
     gene            26926..27654
                     /gene="purC"
                     /locus_tag="ACG8LA_000891"
     CDS             26926..27654
                     /gene="purC"
                     /locus_tag="ACG8LA_000891"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004639 -
                     phosphoribosylaminoimidazolesuccinocarboxamide synthase
                     activity [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HFQ0203207.1"
                     /translation="MEKKELLYEGKAKKIYLTSDENLIWIEYLDQATALNGARKDQIS
                     GKGELNNQITSAIFRYLTQRGIKNHFIEQLSKTEQLAKKVQIIPLEVVIRNIAAGSFS
                     KRLGVPEGKEFIKPIIEFYYKDDQLDDPFINEEHIYFLQLAKPEEISELKAQALAINE
                     ILTELFAKVGLVLVDFKLEFGRSNGQILLADEVTPDTCRLWDERTNEHMDKDVYRRDL
                     GDLIPVYQEVYNRLSELTEEKERV"
     gene            27654..27908
                     /gene="purS"
                     /locus_tag="ACG8LA_000892"
     CDS             27654..27908
                     /gene="purS"
                     /locus_tag="ACG8LA_000892"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurS"
                     /protein_id="HFQ0203208.1"
                     /translation="MYFVKVYVTYKDSVLDPQGEAVKKAVHRMGYETIEDIRIGKYFE
                     IQLADAEEPIDTVIETICDKLLANVNMETYRYEIKKMEEV"
     gene            27910..28581
                     /gene="purQ"
                     /locus_tag="ACG8LA_000893"
     CDS             27910..28581
                     /gene="purQ"
                     /locus_tag="ACG8LA_000893"
                     /EC_number="3.5.1.2"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004642 -
                     phosphoribosylformylglycinamidine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurQ"
                     /protein_id="HFQ0203209.1"
                     /translation="MKFAVIVFPGSNCDADMLWAVREIMGADAEFVRHDESSLEGFDG
                     VLLPGGFSYGDYLRCGAIARFSTIMEEVIRFAEEGKPVFGTCNGFQILTEAGLLPGVL
                     RRNESLHFICKTVPLKVNPKTAFTSEYEADEIIYLPVAHGEGNYFCDEETLQELKKNN
                     QIAFTYNDNINGSVENIAGITNKAGNVLGMMPHPERAVEDLLGSEDGKRFFASILKNF
                     GKVTV"
     gene            28582..30804
                     /gene="purL"
                     /locus_tag="ACG8LA_000894"
     CDS             28582..30804
                     /gene="purL"
                     /locus_tag="ACG8LA_000894"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004642 -
                     phosphoribosylformylglycinamidine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurL"
                     /protein_id="HFQ0203210.1"
                     /translation="MKTLKEPTAEEIKKKRIYAEWGLTDEEYRMIEEDILGRMPNYTE
                     TGLFSVMWSEHCSYKNSKPVLRKFPTSGPHVLQGPGEGAGIVDIGDGLAVVFKAESHN
                     HPSAVEPYEGAATGVGGIIRDIFSMGARPIALLDSLRFGELDNPRTKYLLEEVVAGIG
                     GYGNCIGIPTVGGEIAFDPCYEGNPLVNAMCVGLIEHKHIQKGQAAGVGNSIMYVGAK
                     TGRDGIHGATFASEEFNQEEEQQRSAVQVGDPFMEKLLLEACLELILHHSDSLIGIQD
                     MGAAGLVSSSAEMASKAGSGLILTLDEVPQRETGMTPYEMMLSESQERMLICVKSGEE
                     EKIQELFQKYDLDAVTIGKVTDDGQYRLYHQGEEVANLPVDALAEDAPVYHKEMKEPA
                     RIVEFQQLAPYQPVIEEPGQVLLDLLQQPTIASKRSIYETYDSQVQTNTVVRPGSDAA
                     VMRVRGTNKALAMTTDCNARYLYLDPKIGGQIAVAEAARNIIASGGKPLAITDCLNYG
                     SPDKPEVFWELSTSADGIAAACETLGTPVISGNVSLYNETDGQAIYPTPMIGMVGLIE
                     DHKHITTQEFKKSGDLIYILGKTFADFDGSELQKMQLGRIEGVIRNFDLSIEKRNQEL
                     VLTAIQNGLIESAHDCSEGGLAIALAESAFKHQLGISVQFELSSAQLFAETQSRFVLT
                     VAPENKTRFEEMMGDAAVLAGKVTDEAIIEISATDGQIKIETAVARKCWEDAIVCLMK
                     "
     gene            30789..32228
                     /gene="purF"
                     /locus_tag="ACG8LA_000895"
     CDS             30789..32228
                     /gene="purF"
                     /locus_tag="ACG8LA_000895"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004044 - amidophosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009113 - purine nucleobase biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HFQ0203211.1"
                     /translation="MSYEVKSLNEECGIFGVWGHPDAASVAYFGLHSLQHRGQEGAGI
                     VSNDRGKLKGHRDLGLLSEVFKDQRKLQQLTGEAAIGHVRYATAGNGSVDNIQPFLFK
                     FHDQSIGLAHNGNLINARSLRKELEENGAIFHSNSDTEILMHLIRRSEETDFLNKLKS
                     ALNEVKGGFAYLLMTETAMIAALDPNGFRPLAIGQMKNGAYVIASETCALEVIGARFI
                     RDVQPGEIVIINDEGIQIDCFTKDTQLSICSMEYIYFARPDSNIAGINVHTARKNMGR
                     NLAKESPVKADMVVGVPNSSLSAASGYAEASGIPYEIGLVKNQYIARTFIQPTPELRE
                     QGVRMKLSAVRGVVEGKKVIMVDDSIVRGTTSRRIVHLLKEAGAKEVHVRIASPPLKY
                     PCFYGIDIQTRKELIAANHTIDEIKECIGADSLGFLSEEGLIESIGLEKDAPYSGLCM
                     AYFNGDYPTPLYDYEEKYQESLKEKVSFF"
     gene            32251..33303
                     /gene="purM"
                     /locus_tag="ACG8LA_000896"
     CDS             32251..33303
                     /gene="purM"
                     /locus_tag="ACG8LA_000896"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004641 -
                     phosphoribosylformylglycinamidine cyclo-ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HFQ0203212.1"
                     /translation="MNSMANAYAKAGVDVEAGYEVVERIKKHVKKTERLGMMGAIGGF
                     GGCFDLSVFQLKEPVLVSGTDGVGTKLAVAIEADKHDTIGIDCVAMCVNDILAQGAEP
                     LYFLDYLATGKNDPLRLENVVKGVADGCVQGNMALIGGETAEMPGMYSGNDYDLAGFA
                     VGIAEKSQLLTGETINPGDVLLGIASSGIHSNGYSLVRKIFFEQQQFSLSSKLPELKK
                     TLGEELLEPTKIYVSSLLPLIKEKKIKGAAHITGGGFVENIPRMLPESMAAQIKLGSW
                     PILPIFGCLQKYGEIPEMEMYEIFNMGIGMVLAVQESKVKEIVHEIEQAGEKVYEIGK
                     VIAKEKHRVVFIGEER"
     gene            33300..33878
                     /gene="purN"
                     /locus_tag="ACG8LA_000897"
     CDS             33300..33878
                     /gene="purN"
                     /locus_tag="ACG8LA_000897"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004644 - phosphoribosylglycinamide
                     formyltransferase activity [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HFQ0203213.1"
                     /translation="MRIAVFASGNGSNFQALADYLSKKGLESSIDWLFCDQPEAYVLK
                     RATALSVPADCFSPKEFDSKKEYEEAILHKLKEKKIDLIVLAGYMRIIGPVLLKNYDK
                     RIINIHPSLLPAFPGLHGIRDAFEAGVKETGVTIHYIDQGVDTGPIIRQEKVRIEQED
                     TFDSLEEKIHRVEHRIYPEVISEIIENGGYLK"
     gene            33875..35410
                     /gene="purH"
                     /locus_tag="ACG8LA_000898"
     CDS             33875..35410
                     /gene="purH"
                     /locus_tag="ACG8LA_000898"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0003937 - IMP cyclohydrolase activity
                     [Evidence IEA];
                     GO_function: GO:0004643 -
                     phosphoribosylaminoimidazolecarboxamide formyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HFQ0203214.1"
                     /translation="MTRALISVSDKTGIVAFAQGLIEQGVEIISTGGTKHALDKAGIK
                     TLSIEEVTGFPEMMDGRVKTLHPKIHGGLLGRRDLPSHMEAMETENIQPIDFVCVNLY
                     PFKETIMKPDVEIAEAIENIDIGGPSMLRSAAKNHEFVTSVVDPSDYEEVLSELRQYG
                     HTSLSFRQKLAAKVFRHTAAYDALIAQYLTDWVEEKEPEKLTLTYERKQTLRYGENSH
                     QAAAFYQSALLEKYSIAAAKQLHGKELSYNNIRDADAALRIMKEYDEPTVVALKHMNP
                     CGIGTASTILEAWEAAYEADPVSIFGGIIVLNREVDLPTAEQMHKLFLEIIIAPSYTQ
                     EALELLQKKKNIRLLTVDFAQEENQNREETVSVLGGLLVQDQDLAIENEEEWKVVTKR
                     KPTPAEAKALAFAWRAVKHVKSNAIVLANERQTVGIGAGQMNRVGSVKIAIEQAQEKM
                     EGAVLASDAYFPMDDSVEYAAKHGIKAIIQPGGSIKDQDSIDMANKYDLAMVFTDVRH
                     FRH"
     gene            35426..36700
                     /gene="purD"
                     /locus_tag="ACG8LA_000899"
     CDS             35426..36700
                     /gene="purD"
                     /locus_tag="ACG8LA_000899"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004637 - phosphoribosylamine-glycine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0009113 - purine nucleobase biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HFQ0203215.1"
                     /translation="MNILVIGAGGREHAISKKLLASPKVDTVYCAPGNPGMTKDGINC
                     VAISERDHSALIHFVKKEAIDWSIVGPEVPLLNGIVDDFMAEGLKIFGPTKAAALIEG
                     SKSFAKQLMDTYQIPTAKSRSFECYEKAAAYIKENGAPIVVKADGLAAGKGVVVATTV
                     KEALDAAEQMLNQHRFGDSSKKIVVEEFLAGEEFSLLAFVRNTKVYPMVISQDHKRAF
                     DNDKGPNTGGMGAYSPVPQISKKMIEKAVEEVLKPAALGMKELGRSFTGVLYAGLIAT
                     KEGPKVIEFNARFGDPETQVVLSRLKSDFAQVIDDLLENRTVELKWQQEGYNVGVVVA
                     AAGYPEEYETGMVLPDFLEEELSVYYAGVSSNNGKLVGAGGRLYLVEAYGETIKEAQK
                     KIYTALMDKTTDGTFYRTDIGEKAANSELIVK"
     gene            36822..37736
                     /locus_tag="ACG8LA_000900"
     CDS             36822..37736
                     /locus_tag="ACG8LA_000900"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HFQ0203216.1"
                     /translation="MKKIQLGTSDQKAAAVILGCMRINNAEDPVKVIETAYENGIDFF
                     DHADIYGNGECEEIFADALAKTSIKREDLFIQTKCGIVPGVMFDFSKKHIIESVEKSL
                     TRLKMDYVDALLLHRPDTLVEPEEVAEAFDELERSGKVRYFGVSNQKPMQIELLKKYV
                     RQPLVANQLQFGLKHTGMIDQGIHVNMTDEASIDHDGSVLDYSRLHDMTIQAWSPYQY
                     GFFEGVFIGNEKFPELNQTLEELAAKYQTTPTGLASAWILRHPANMQVIAGTMNVGRI
                     KEIAQASEINMSREDWYELYRAAGNILP"
     gene            complement(37869..39434)
                     /locus_tag="ACG8LA_000901"
     CDS             complement(37869..39434)
                     /locus_tag="ACG8LA_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0203217.1"
                     /translation="MYKVFIIEDEYLIRNNLREQITVLGSYYPITYVGEAGDGEMALS
                     SIIDLQPDIILTDIQMPFMDGLTFSKEARKLLPWTRLIFISGFDDFDYMKGAIQVQAD
                     DYLLKPIKSSELKQAIEKAVTALDLQQKETHTSSDLVFELKKNHFLNGLFKGSLTISE
                     TLKLAESFNRSLAGKKMTVLLAANQVSTDFEDYAHLSDYLKFLFRENQQVIFSAVSSR
                     FIKFLIVDSLEENVIETSYQVAQTLVHELEKGQKNNFSVAIGPVAERISELPASFEIT
                     QMILETASSLKEQIISYEDLIQEAKLPVDSVFYFDLSLDLSSLSKNEVSKYIEHLTKP
                     QGTPTRTRLYRLFVLTKLLQHVCLKEKKIPQEMVHCTSTSQRLAISADDSLYRSTVYM
                     FISFLTALPSQPSRNKYQPILNHALDFIKENFTDPDMSLTWVAQQVALSPSHFSTIFS
                     QSFNQTFIDYLTEQRIELAKKLLQQSDYRISDIAFEIGYNDPNYFSYLFKKKQGISPK
                     EYRTQLFLKNKNN"
     gene            complement(39427..40878)
                     /locus_tag="ACG8LA_000902"
     CDS             complement(39427..40878)
                     /locus_tag="ACG8LA_000902"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFQ0203218.1"
                     /translation="MTKNLSIKQIFAQANKAMLLFAVIPLLLSILLYSQQLLIYQQTI
                     ANIQKADAIALKVDQKVLESMWDLISGQVTVDEFNEENILEELRNDIREIKNNTNTLK
                     EISTLDVSLRTIDTLEDYQNELINNILAKDFMDTNEEIINQVDSVTQLLSDILQDFVR
                     VEIDLASKKNTTLVRSLILLTIVELGVLSTIFFYAKKNRRFLERKVQEPINQLIEMSE
                     QLSSGNLGFRLTLPETLELQTLTASMNKMAEDLNQSLRENALKQYHLAQSEVRVLQAQ
                     ITPHFIYNSLDAIISLIEQDCFEEALTMTHALSGFFRTSLSKGQDWIPLEKEISHIND
                     YLVILKIRYGHMLDYKIDIPETLFPVSILKMILQPLIENAVYHGTKYVRHKGFIRITT
                     CKIDEMIQFKVIDNGIGIPAEKLAEIRKELAKGIDSDFSIGYGLYNVNKRLLLYYGND
                     QKPITIDSKYREGTTVTLMIPLSPKTIGGNKHV"
     gene            complement(40892..41908)
                     /locus_tag="ACG8LA_000903"
     CDS             complement(40892..41908)
                     /locus_tag="ACG8LA_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFQ0203219.1"
                     /translation="MKRVLFFLALVVIAYQMMGCTPNTKEAPDPLVVGFSQSGTESSW
                     RKKHTESIITALEKEDYQVLYRNGYMNQERQIQDIRTFIAYKVDMIIFTPLQESGWDS
                     VLKEAKRAGIPVILVDRHIQTNDPELFVTHIGPSFKAEGNRAGLFVSNHFTNSKKQEI
                     RILELAGSENSTPTKLRSEGFLESINRKPTLKKDGTIDHKPPMTIVHRIVGDFIRMKG
                     KDQMKRYLETNDLSEIDVLYSHSDEMTHGALAAIKETSIKPGEDLIIVTIDGQEDMIE
                     KLRSGIVNCVVECKPDVGWYVANTVTRYFGNIQTGKTLPKDIFISETVFSQQNIANIP
                     TRNY"
     gene            42128..43216
                     /gene="chvE"
                     /locus_tag="ACG8LA_000904"
     CDS             42128..43216
                     /gene="chvE"
                     /locus_tag="ACG8LA_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multiple monosaccharide ABC transporter
                     substrate-binding protein"
                     /protein_id="HFQ0203220.1"
                     /translation="MKNKFRKIVGTIAILTASILLSACGNSGSADDSTGYVGIAMPTK
                     SAERWIADGNNMVSELEKLGYKTDLQYGEDKVENQVAQIENMITKGVDTLVIASIDGS
                     ALTDVLAKAKEADIKVIAYDRLLMNSENVDYYATFDNFGVGVSQAAYIEEHLGLKEGK
                     GPFTIELFGGSPDDNNALINYNGVMSVLQPYMDNGQLVVPSGQTSFSQIATLRWDGST
                     AQARMDNLLSANYTDQTLDAVLSPYDPISLGIISSLKGVGYGSESKPLPVITGQDATV
                     AGVKSIIAGEQTQTIFKDTRILAKNTIEMIKAISDGEEVPVNDTETYDNGVKTVPTYL
                     ANTVSVDKDNYQAELIDTDYYKESDLKN"
     gene            43270..44796
                     /gene="mmsA"
                     /locus_tag="ACG8LA_000905"
     CDS             43270..44796
                     /gene="mmsA"
                     /locus_tag="ACG8LA_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multiple monosaccharide ABC transporter
                     ATP-binding protein"
                     /protein_id="HFQ0203221.1"
                     /translation="MADCILKMADITKKFSGIRALDCVNLMIERGEIHALCGENGAGK
                     STLMNVLSGLYPYGSYDGEIFYDGKLCQFKDLKDSEEKGIVIIHQELALSPYLSIKEN
                     IFLGNEQAERGVIDWELTEKKTYELLNKVGLSIDPNLLVSQIGVGQQQLVEIAKALSK
                     SVRLLILDEPTAALNEEESANLLRLIRELKEQGVTSIIISHKLNEIVDIADRITILRD
                     GQTIETLENEMISEEHIIRGMVGRDLVDRYPERKPDIGEVYFKVEDWTVYHPLDHERI
                     INDHINLHLKKGEIVGIAGLMGAGRTEFAMSLFGHSYGSKISGRILKEGAEISVKTVP
                     SAIANGLAYVSEDRKSLGLNLLMDIRENVTLSSLDKISQKGVLDKEKEVTEAENFRKK
                     MRIKTNSIHQIVSSLSGGNQQKVVLSKWLMTQPDILFLDEPTRGIDVGAKYEIYTIIE
                     EMAANGKAVCLISSELPEILGMCDRIYTMNEGRITGEVSREDADQEVLMKLMTKEEVG
                     "
     gene            44798..46003
                     /gene="mmsB"
                     /locus_tag="ACG8LA_000906"
     CDS             44798..46003
                     /gene="mmsB"
                     /locus_tag="ACG8LA_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multiple monosaccharide ABC transporter
                     permease"
                     /protein_id="HFQ0203222.1"
                     /translation="MEQAKNLTDKKEKKLNLKSRAADLFGRYSMVIILAGLLIAFQLM
                     TDGIFWRPLNITNLVLQNSHILVLAAGMLLVVLLGHVDLSVGSVMAFVGAIAGMMMVN
                     RQMNPWMTVIACLAVGGLIGAWQGFWVAYAGIPAFIVTLAGLLMFRGLTQVVLGGQSL
                     APFPAVFQKMSTGYLPDLSEGSSLHFLTLILGMIITIVLVVGQWRTRNRRKNHLFEVE
                     SPTAFLVKAVFTAVVVLGITYIFASYQGYPIILIILGLIVAAYGFLTNKTVAGRQIYA
                     TGGNRKAAELSGIKTKRITFWVFVNMGVMAALAGLVLAARLNAATPQAGTSMELDAMA
                     AVYFGGASTSGGIGTIMGAIVGGLVMGVLNNGMSILGVGVDWQQAIKGLILLLAVVLD
                     LYNKKKRTT"
     gene            46260..47237
                     /gene="guaC"
                     /locus_tag="ACG8LA_000907"
     CDS             46260..47237
                     /gene="guaC"
                     /locus_tag="ACG8LA_000907"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902560 - GMP reductase complex [Evidence
                     IEA];
                     GO_function: GO:0003920 - GMP reductase activity [Evidence
                     IEA];
                     GO_process: GO:0006163 - purine nucleotide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HFQ0203223.1"
                     /translation="MKVFDYEDIQLIPNKCIVNSRSECDTTVTLGKHTFKMPVVPANM
                     QTIIDETIAEFLAENGYFYIMHRFDEAARIPFIKKMKKRGLITSISVGVKKEEYSFIE
                     KLAEESLNPDYITIDIAHGHANSVIDMIQHIKKYLPETFVIAGNVGTPEAVRELENAG
                     ADATKVGIGPGKVCITKIKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIAKS
                     VRFGATMVMIGSLFAGHEESPGETKVENGIVYKEYFGSASEFQKGEKRNVEGKKIWIQ
                     HKGSLKDTLVEMQQDLQSSISYAGGRDLEAIRKVDYVIVKNSIFNGDTI"
     gene            47501..48925
                     /locus_tag="ACG8LA_000908"
     CDS             47501..48925
                     /locus_tag="ACG8LA_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HFQ0203224.1"
                     /translation="MWEKVEKKQGPIYRQIMEQIMREIENGRINPGSQLESERKLGQL
                     FGVNRSTVVHALEELRELGVLTSKRGSGWFVNQTEWGKFAVPRIDWRQMISPRYEQTD
                     WYEQKIREAKQIQKTSFLDLYASEMPDELLPNFEFPSYSLEEILAEEKEMDLLGYTPL
                     RNKIKRYLESKFELAFSPNQLLVTGGGQQAIFLILQTILSAGEGIAVESPSFFYRLPL
                     FKASGTRLFGIPMDEEGIDLEKLKESIHKNKLKAVLINPNFQNPTGKVMSQKRREKLV
                     ELCRQYRLPIIEDDVFTDLSFLNQEEVLPIRTIDPDNVLYVGSLSRVLGKTTKIGWVI
                     GPETFISQLAQAQEMMEFSMNILTQITVANVFNEAIDLKMQDVRKKLKEKSRLISAWG
                     DSQSFFKLHSILGGYYAWITWDGKKLDPELAEKVVDMGLGIAPSLLFGQDINGIRINY
                     SRLDENQIPLFYSKMKILEKWLTE"
     gene            complement(48967..49224)
                     /locus_tag="ACG8LA_000909"
     CDS             complement(48967..49224)
                     /locus_tag="ACG8LA_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0203225.1"
                     /translation="MPIRILTALVNKITIRKAFYISSAFFLFSNQTYNHLFLFKNVGV
                     IQFCCKHLFYLHIVNGRTNNGFFLVSLYRILFPKKKKQLEI"
     gene            49386..50495
                     /gene="pdhA"
                     /locus_tag="ACG8LA_000910"
     CDS             49386..50495
                     /gene="pdhA"
                     /locus_tag="ACG8LA_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045254 - pyruvate dehydrogenase complex
                     [Evidence IEA];
                     GO_function: GO:0004739 - pyruvate dehydrogenase
                     (acetyl-transferring) activity [Evidence IEA];
                     GO_process: GO:0006086 - acetyl-CoA biosynthetic process
                     from pyruvate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase (acetyl-transferring) E1
                     component subunit alpha"
                     /protein_id="HFQ0203226.1"
                     /translation="MANKKAPIDFQALLDEVNADFPVYQALDQDGNVVNKDLVPDLSD
                     DELVELMTHMVWSRVLDQRSTALNRQGRLGFFAPTAGQEASQLASAYAFDKEDVLLPG
                     YRDVPQLVKHGLPLSQAFLWSRGHAAGNSYPEELKALPPQIIIGAQYVQAAGVALGLK
                     KRNKKNVVFTYTGDGGSSQGDFYEAINFAGAYHANAVFYIQNNGYAISTPREKQTAAK
                     TLAQKAVAAGIPGIQVDGMDPLAVYTVSKMAREWAISGNGPVLIETLTYRYGPHTLSG
                     DDPTRYRTKDTDDDWQKKDPLIRFRKYLTEKGLWSEEKEEQVIEATKEEIKAAIAEAD
                     KVPKQKVSDFLKNMFEVSPQSIKEQIAIYEAKESK"
     gene            50498..51475
                     /locus_tag="ACG8LA_000911"
     CDS             50498..51475
                     /locus_tag="ACG8LA_000911"
                     /EC_number="1.2.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HFQ0203227.1"
                     /translation="MAQKTMIQAITDALALELENDENVVVFGEDVGKNGGVFRATEGL
                     QEKFGEDRVFDTPLAESGIAGLSFGLALEGFRPVPEIQFFGFIFEAMDEVVAQMARTR
                     YRMSGTRNLPITIRSPFGGGVHTPELHSDNLEGLIAQSPGIRVVIPSNPYDAKGLLIS
                     SIRSNDPVVFLEHMKLYRSFREEVPDEAYEVPLDKAAVTREGTDVSIITYGAMVREAI
                     KAADNLAKENISVEIIDLRTVAPLDVETIIQSVEKTGRVVVVQEAQRQAGVAAQVVSE
                     ISERAILSLEAPIGRVSAPDTVFPFGQAENVWLPNAKDIEDKVKEIAEF"
BASE COUNT        16256 a         8998 c        11273 g        14992 t
ORIGIN      
        1 aatcacttta cataagtttc aaaagtttct ttaatttcct attgttcaat aagtaacaat
       61 gtaaagataa aattaaaaat gttaatacgt attagcaaaa taaaagcttt ttttattgtg
      121 aataaatgaa cataattagg aggagaaaga tgaacttatt tgacattttt cgatcgactt
      181 tgacagatat gtcgattgtc agtgcaatca cttcaacagt ttttattata ttattagggt
      241 ttgtttgtag aaaaaagggg attttttctg aatctgttgg aaaaattcta tcgaaagtcg
      301 tcttaacagt ggctttgcca gcactggcat ttcgagcttt catgcaagat atcaatacag
      361 aattactgat gcaaggaatc aatgtcttga tttggggatt agttatttat attattctta
      421 ttctagtttc aaaacctttt ttcttaagct ataaagggga taagcaaaca acgttgcgtg
      481 tcctgacgat ctttggttct acgacctttt tcggaacgcc tatcgtcagt gcgatttatg
      541 gtcctgtcgg cgtgatgtat tcctcaattt tcaatattgg ctaccgaatc tttttgtatt
      601 cttatggata cataaaaatg agtggcttga agatggaagc taaaaatatc aaagcgatgt
      661 tcgtcaatcc aatcattatc gctacttttg ccggcctttt catttggctg ttccaagggt
      721 atctgccaca agtgtcagtt acaggtgcag aaggagagat aagccaagta gcgtttttgc
      781 gaattgacca gactgcaccg tggctatttc agccgatgga ttatttagct ggtttaagtt
      841 caccattggc gtggctagca atcggcgcaa cattaggtga agtaagcttc aaaaaagctg
      901 catctgaaaa aacttcatgg tattacagtc tagtcaaagt ggtatttgta cctgcattga
      961 atatcgtgat tctagcagtt ttgacggcaa cgaatattct accagtcaat tttgaagcac
     1021 tggcaacaat cgttatcatg atggctacac cagctgcaac agtggcagca gcctatgcta
     1081 tcagttttga tagggaggca cttttagcct ccaatgcatc cttactgtca actatttttg
     1141 ctgtggtact gacacctgta tggatcgttg tattacaaat gattcatggc ataggtttat
     1201 tttcataaga aatggaggaa gaaagtatga gaatcgcatg ttacggtgtt cgtccgaacg
     1261 agatagattt ttttgaaaaa ttgaatattt accattatga tctcagtctt tatgaagaac
     1321 tgttgacaca tgacaatatc gtgtcagcaa aggaccatga tgctgtattg ttgaggggaa
     1381 attgtatagc agatgagacc aatcttgcaa aaatgcagga atatgggatt cgttatgttt
     1441 ttacacggac tgtgggagtc aatcatatcg atctacaagc ggcagctgat tttggtatga
     1501 cagtagcccg tgtaccatcg tattcgccaa atgcgatagc agagttatct ttgacttttg
     1561 ccatgatgct tttgagaaat actgcgtata cgacgatccg aacatctttc aaagattttc
     1621 gagtggatga gcaaatgttt agtcgtgaaa tcagaaattg cacagtaggg atcataggaa
     1681 caggcaggat agggttgacg gaagctgttt tgtttaaggg actaggagcc aaagtgatcg
     1741 gctacgatat tcatcagaca gaagctgcta aaaaagtatt gacgttccac tcgcttgaag
     1801 agttattagc caaaagcgat attgtcagta ttcatgtacc tcatatccca ggtgaaaacg
     1861 atcaaatgat caatgaagga tttttagctc aaatgaaaaa aggtagcatc ttgattaata
     1921 cagcccgtgg agagcttcaa gataatgaag ctattttaag agctttgaaa agcaatcatt
     1981 tagctggttt tgcaaccgat gtttttgcaa atgaaacaga ggtttttttc cgatccttca
     2041 agccatggga gacgattcca gaccctgcta tccagcaatt agtagaaatg taccctagag
     2101 ttcttgtaac cccgcatgta ggttcaaata cagatgaggc attatcaaat atgatttcga
     2161 caagtttcga gaactttcgt gaaataatag aaactggaaa aacgaaaaat gaggtatctc
     2221 ttcctaaagc ccgtcaatta agataagaaa acatggatat tcgtcaataa aatgtttaaa
     2281 aatagtccaa gtaaacagtt gttacttctg tatacttgga ctattttgta tgggataatt
     2341 cgatgactca acagtaatct gtgagctttt tccgcccatt ctttgtcaat tcataacagg
     2401 ttagcggccg gccgatttcc aaatatttga ttctttcgtt caatatatct tgttctacta
     2461 aaaaattcaa atatttcttg acggatatac gtgacagtga gcttttttga gccagttctt
     2521 ttgttgaaaa aatagtatct tcttttagaa taaatgcact tatttttttt aaagtcagtt
     2581 ttgacagacc tttaggcaaa tcgatgaatg atggtatttc gtgaatggga gtggtgtggt
     2641 tgaatacttg atcgatcaat ttctgatcgg ctttttcagt cgtttggatt gtctgagaga
     2701 aagcaagata cttttcgatc gccagctgaa aacgttgcaa agtgaacggt ttgatcaaat
     2761 aatctaaggc accgtagcgg atcacattct ttatggtttc gatatcatct gcagcagtga
     2821 tcaaaatcac tgggatatca tttccttgct gtctaagcca agataaaaaa tggataccac
     2881 tttcgccagg catgtataca tcaagcagca gcagatctgc gtttttttgt ctgaaatatt
     2941 tttttccttc ttctacattt ctgaaacttt cgattacgtt catattaggg atgctttcca
     3001 caaaagtacg attcaattct gcaaccattg gatcatcttc gattatcagg acatttgtca
     3061 tcattttgat cttccttttt tggtaattct agatagacga ttgtaccgcc atttgtttgt
     3121 ttggaaaatt ctaaaaatcc accgtggcgt ttgacgattg aatggatgag attcaatcca
     3181 aacccacgat tgattccctt cgtcgaaaaa cctagcgtaa atattttttc tgagatttct
     3241 tctgatatcc cgacaccgtc atcgcagacg gtcacgatga atacttcagc ttctgtgtca
     3301 tagtttaaat gaatccggac ctgtccgttt ctttcatgtt tttgtagcac ggcttctttt
     3361 gcattatcaa gtaagttccc taacacttgc aaaagtgaat ggatggagtc atccatctcc
     3421 attttaggga taaaagaatc gctttctaac agcatttcaa cagattgttc tttggcttcg
     3481 tttattttgc ctaataaaaa accggcaatt gcaggtactt tgatcagact tgagacttgg
     3541 ccaatctctt ttttataatt ttgatttagc tgctggataa aatgggtgac ttcttcatac
     3601 ttcttcaaat caatcaaacc agaaatgaca tgaagtttat tcatgaattc atgggtttga
     3661 gctctcatgg agtttatata ttgtttcgtc cccccaagct cctccattaa tttcattact
     3721 tctgatcgat ttcgtaaagt tgcgactgct cctaaaaaac ggtcattgct aaaaagaggt
     3781 gtaacgctag aaatagtttc tatcccattt aaatacatgg attgagtccg aacggtcgtt
     3841 tgatgctcaa tcgtctcttt aaacaaaacg tcatatagat tatcactgat ttttttccta
     3901 cttcgaaatc caatagctgc tctgtttggt agaaaatgtt ttttgcaggt gtattgatca
     3961 agaggatagt tttatcagaa gagatggcta agattccttc atctacttca ttttcgataa
     4021 tcgttttttc acttaactgt tctgctattt cttgtggttc aagtccaagc agtacttttt
     4081 tcattttttg ggcaagaaaa acggcgccta tgatgcctac gctaagtcca ataatcaatg
     4141 aaaaaacaat cattttttgt ccatctttga cttgattgtc aatcgtgttg tttgttaagc
     4201 caacacaaac tgcaccaata atctcttgat cataataaat agggacgaaa tagcggaagc
     4261 cgaaccctaa cattccttct ttttcagaga aaaattcttg tcctccaatc acttttttca
     4321 catcttcatg acttgagaaa ggaagaccga tgtaacttgg gtctgcgtga gaatatcgaa
     4381 tgccttcagg gtccatgaca acgataaaat ctaaattcga tgcaatcatg atttcatttg
     4441 ttattccttg aatcgcatgt gtcgggtcac cagtctgcag ctttttttgg atgagtttat
     4501 cattggcaac gattttagca atgctagaga ttttatctga cacactagat cggttcatcg
     4561 aaagaataaa attcctgatc aatatggcag aaacaatcaa agaaacgaat gtggagaaac
     4621 aaacgacaag gatgatcgtg ttctggagct ttaatggttt tttcttaaaa aaaggaaaca
     4681 taggctacct cgaaagaatt tattgtgaaa attttaacat gaaaacaaaa atttaacaaa
     4741 ttgtcaacga taaacacaac cttcctataa aaaacaccac tgagtcggta aaagaagcta
     4801 tacagaattt tcaaacattg gtatgataga cgtagaaatg gaaggaggcg tgtatatgat
     4861 agggggaatc gcacttgaga cgatttattg gtatacattg ctgatttgtg caggattggc
     4921 agtcctattg attatttttg gagatgtatt cgattttgat ggcccgcttg atccgatgct
     4981 tattatccct tggttaactt tcacaagctt atttggtttt ctaggtgagc gtttaacaga
     5041 tcaatcatct ttatttttat ttattgctag tggaggcata tcgatagtgt tggtattttt
     5101 gcttaatttc tatatattga tgccgatgaa acatgccgaa tcaacgatgt cgtcttctga
     5161 aaaaactctg gaaggacaag tagctgttgt gatcacaccg atccctgtac gaggtatggg
     5221 agaaattcag ttgaaaagtg ttaccggttc cattagtcgt ccagcttgtt tttacagccc
     5281 ccaagaacag acagctgagc ggggaacgaa agtattgatc attgagatca aggaaagaat
     5341 ctgttatgtc atgccttatg aaagcatgat aaaagcttaa aggagcgtgt gttaaatgga
     5401 aataccagtt gtttttatcg cgatcgcaat cgcagctttg attttactga tgttgctgat
     5461 cgtctttgta gcgaagtacc agacagcaaa accggatgaa gcgttgatca tcagtggaag
     5521 ttatttagga agcaaaaatg tgcacattga tgaaagcaat aacaaaatca aaattgtgcg
     5581 tggaggtggc gcattcgtct tgccagtttt tcaacgttcg aatcggatca gtctattatc
     5641 gagtaaattg gacgtctcca cccctgaagt gtatacggaa caaggcgtac cggtgatgtg
     5701 tgatggtact tcgatcatca aaatcggttc atctgtagaa gagattgcta cagcagcaga
     5761 acagttttta ggcaagacaa gagaagaact ggaaaatgaa gcaagagaag tattagaagg
     5821 acacttgcgc tcgattcttg gttctatgac tgtagaagaa atctatcaaa atcgcgataa
     5881 gttcagtcaa agcgtacaag aagtcgcttc tgtagacctt gcaaaaatgg ggttgatcat
     5941 cgtttctttc actatcaaag aggtcagaga caaaaacggt tatcttgact ctttagggaa
     6001 accaagaatc gcccaagtca aaagagatgc agatatagca gaagcggaag ctctaaaaga
     6061 aacgcgtatc aaaaaagctc aagcagaaaa agaatcacaa gcagctgaat tacagcgaca
     6121 aacagagatc gcagaatcat taaaagaaaa agaactgaaa ttagcaacct acaaacaaga
     6181 acaagatgtt gctaaagcaa aagcagacca agcctacaat ttagaaagtg cccgagcaca
     6241 acaacaagta atcgaacagg aaatgcagat taaaatcgta gaacgtcaaa aacaaatcga
     6301 actggaagaa aaagaaatca cacgtcgtga aaagcaatat gattcggaag tgaagaaaaa
     6361 agcagatgcc gatcggtacg ctaaagaaca agaagcacaa gctcaaaaag tcaaagaagt
     6421 gactgaagcc gaagcagaac gattccgtgt ggaagcactg gcagaagcgg aagccaataa
     6481 gacacgttta gctggacaag cagaagccga agcagcacta gcaaaaggaa aagcagaagc
     6541 cgaagcaaaa caaaagatcg ccaatgcctt caaggaatat ggcgaagcag ctgtcttgag
     6601 tatggttatc gatatgctac cgcaattgat gcgcgaagca gcacagccgc taggaaatat
     6661 cgaaaaaatc tctgttgtcg atacaggaag cagttcagga gaaaccagtg gagcgaaccg
     6721 agtgacaaat tatgccacaa atttgctttc ttctactcaa gaaacactaa aagcgacaac
     6781 aggacttgac ttgaaggaaa tcgtagagaa tttgtcgaca cgtgggacta ctagccaagt
     6841 aaatatgtat gaagcgccaa aagaggcaga acaaaactcg atgaaggaag aataaagtag
     6901 tacacttcac cgttcaatca aaaatggagg aagacttttt aaagttcttc tctccatttt
     6961 tttattttat tgcaaaagaa aattagtcct cgctattttt cttttgtttt tggatcttag
     7021 cttctatctc ttgtaaattt gttcttagca atcgttcttt cttttggagt tcgaccaaat
     7081 cttctgatag ttcttccttc ttttctgttt caggaggacg aagaaagaaa ttgataccga
     7141 ttgcaatgaa tgtccctata aaagtatcta gtacacgttg gatagcatac aaagcggatt
     7201 cgccttgagg gatgctcaac gcaatcagca acaacgtagc tattgcggaa atgataccgg
     7261 aattattgtt aataccatct gacacgacga tcacaataat aactagaata ggaagcaaga
     7321 tcaattctac caaaaaatca ttgtgaaaat agcttttgac aaaaaaataa atgatagcta
     7381 atgtaccacc taatgtattg ccgatgatcc tagactttcc aaaagaaacg gttgtagtca
     7441 agtcctgacg caaagaaaaa acagcagata atgcagcaat catcgggatt cctcgttgag
     7501 tcaaatgaaa aaacaagata cataaaaaaa cagctaaggc acttttgatc gtacgcatac
     7561 ctagtcgaaa acggccaaat tgcatagaga ttctcctttt tggtcttttt actatcatac
     7621 ctaaactttt gtctgatagc tagtttttca ttattcaagt ataattaaaa taaaaaaggg
     7681 ggaagtaaat gcgtatagga atgcgaacag tcaaaacagt gatcagtgtc ttcttttcga
     7741 tggtcacagc gggtagctta tcgctgttgt attggccagc tgcagggatc attgcattat
     7801 taagtgtagg aaataccaag cgctctacat tgcgtacggg catgaatcga atcgcagcct
     7861 ttatattagc tacggcaaca gcactgttca gtttttttgc tgttgggtat actatttttg
     7921 gcttcagtct ttttttattc ctgttcatcc cgcttgcctc tcgcttcaaa ttaaccgaag
     7981 ggatagtagt aaattcggtt ttggtcactc attatttagt ggaggaaaac atgtcttggc
     8041 agctgatcgg caatgaagcg ggattaatgg cgattggatt agtatttgct ttgcttgcaa
     8101 atgtttacat gccagatcgt acgaagcagc tgaaggaaaa ccaaatacag atcgaaaaag
     8161 aatttcgaaa tattttgaga caaatggcag aatttctttt atcagaaaat aaagaagatg
     8221 tgcagatcaa atgcgaacat ttactgacat tcattcgcga aagccaagaa gatgccagag
     8281 aacatcaaga aaactactgg ctcagacagc cgctatacta cgaaacttac ttctctatga
     8341 gaagagcaca ggccaatgtg attaaagaca tgctggaaaa tctagagaga atccagcaac
     8401 cagcttatta tggaaaacat atctatggtt tattgattta tactgcagaa acattttcag
     8461 agtcaaatga tggcagacaa attttaacac gtattgaaga agtttatgta ttgtatcggc
     8521 aaatgcctct gccgactagt cgccctgaat tcgaggatcg agcagaattg ttccagtttt
     8581 tgcagtcttt taaaagtttt attgaaatca aggcagaatt ctcccaacaa aaaatccaaa
     8641 aatagaggtt gtgaattcag ctaatattca ggtcaaaaag ctgatttcac aacctcttct
     8701 ttaaacggtg ttctcctgtc aactcctcgg tcacaagtca caatattcaa caaacatgag
     8761 aagctgtttt ttgaaattgc tccttgtgac tcggagctga acggtaggct cacaacctct
     8821 ttcttaaacg gtgttcaaaa gctttcctct gcggtaataa gtccagccaa acgaaaaata
     8881 ggaggagcta tttttgtttg gctgttctta ttacttgatg cagaacagct ttttcacaac
     8941 cttttaaaat tacatatttt tccatagaac ttgcatttga tccaagattt cgatgacatc
     9001 ttttgtcaag aagagagagc gattgggcaa gtcaccttca atcatgtgta ccatattctt
     9061 tatttcgtaa ttcattgctt cagatgtatt cccgctttcg atgaattcct ttgtaccatc
     9121 tgtaaataag atctccgcac gatcagcacg cgggtaatca gcaatcgtca cataaccgtt
     9181 ctcaaaggca acgataccga cttttggcat ttttgcctga aaagtcaagc tgacagcagc
     9241 aagttcattt tctttgttac gcaagatagt gacggattgt tcgtccacgc ctgtttcaaa
     9301 aggaaccatt gtagaggcaa ctacttcagg ttgagagctc aaaaagaaac gagcgaaaga
     9361 tacagcatac gtaccgatat ccaacagagc tcctccagct aattctggat tgaagaaccg
     9421 gtttttaggg tctggttctt tgtaactgcc gaaaggtgct tggatcattt ttaaagcccc
     9481 cagttttcct gtatccatta ttgagcgtaa ctgctgataa agtggcatgt tgaagattgt
     9541 catcgcttct gctaagatca aattcttttc ttctgctaag cgcatagcgt cagccagttc
     9601 ttttttattc atcgtgatgg ctttttcaca tagaacgtgt ttgcctgctt ccaatgctgc
     9661 caagatatgg tcgatatgct gtctatttgg tacagcaatg tacacgatgt cgatttcagc
     9721 atcgtctaac atttcttgat agcttccgta agcttttgga atattgtaac ggtgagcgaa
     9781 gttttccgct ttttctgaag ttctggaagc aactgctgtt agttcgctcg tctcttgatt
     9841 gaagctttcg gcaaactcat gtgcgatggt accaagacca acgattcccc attgatattt
     9901 tttcatctga aaacgctcct tcatagttgg attgagtttc ttgtctgtct attattataa
     9961 caaaaatcac gaagaataaa gaggagagga cttgaaacat taaaaaaaat gaaagcagcg
    10021 atttaagagg tgctttttga tcaaaactta agtagaatag ttaaaaggag gggataaacg
    10081 tgcatcaagt atatattgat cttattatga gtgtattatt agaacagttt gaaactgaaa
    10141 aaaatttttt agatgaatac ttgctgatca gtccagaaca atggcaaaaa tggaaagatg
    10201 gcgagaaaaa tctgccatct gaagcgatgc agaaagtaaa aaatcttttc actgattatg
    10261 aatggatgct aacgcaaaag attttgcgtc aaacgattat ttttcccgaa aaacgaaacg
    10321 ttgccgttgc agagtacaag caaatcaaaa cacgcatcgc gcaaaaatgg cttagcagca
    10381 aagcagcaaa agtcgagctg atccctttga aaaataatca gcaggctggt agataccttg
    10441 acttgaaagt aagtattcaa tatgatgaat ggggctatga tgatattttg aattttcgtc
    10501 tgccagcaga tgttcaaaaa cagatcgaag gagaaaaaat cgaacttctc gattgggtga
    10561 atgaaaatct ggaagaaact tacgttcatg aggcgaatgg ggaacgtgaa gaacaacgaa
    10621 aggatttttc aagtgaataa atttttagga tttggagcag ttgtgattat gatcgcagca
    10681 atgggctatg ttatttttag cgatgatgat tcgcatgttc aagccggcaa tcaagcagtc
    10741 gaacgaacaa gcaccaaaac aactgctagt aaagaaaaga acagtcaaac aaccagcagc
    10801 aaggtaaagg acaaagaaac aaaagatcgt acgtccaaac aattgccaga tgttaaaaca
    10861 gacgattgga agctagtttt ggttggtcca gatcacaaat tagaaaaaga aattgatgag
    10921 tctactcaat tggcatcatt aagtaacgga tacttgatcg acaaacgcat tgctccagaa
    10981 tatgaagcat ttgccaaggc tgctgaagca gctggatttc cattagtgat ggtctcagct
    11041 taccggtctg tatcatccca acaacaagtt ttcgaacaaa atgtccaaga tgtgatgagt
    11101 cgtcaaggtg tatcagaaga ggaggcgaca aagattacta aagaaacgat tacggagcca
    11161 ggatacagcg aacaccacac aggtctggca gtcgatgtcg tcgatcaaaa ctggtacaac
    11221 agttatcctt ctactgtatt ggatgcaagt tacggagatc agcctggagc taaatggatc
    11281 gcagataatg ctgcgcagta tggatttatc gttcgttatc caaaaggaca cgaagatata
    11341 actaagatca catatgaacc ttggcactta cgttatgtcg gtaaagaaaa cgctgagtat
    11401 atcaccaaac accaattgac gctagaagaa tatctgaatg aattaaatga aaagtaggaa
    11461 ttgatcatgg cgaaaaaaaa gtggaaaaag caaaagcgca agaatatccg ttggccagca
    11521 gtggttgccg gtgtagcagt gatactctta gcctttgttt tttccttgaa gaatctgtct
    11581 tctcctttta ctgataatca gcaagaaaat gaagcgcaat cccatcagca atttattgaa
    11641 cggcttgttc cgcatgccca agaactacaa gatggttatg gagtgcttcc tagtatcatt
    11701 ttaggacaag ctatattaga atcaaattgg ggaaaaagta ccttggctag caaatacaat
    11761 aatcttttcg ggatcaaggc ttatggggat cagaagaaag taagcctgga aacaaaggaa
    11821 tttgttaacg aagaatggat aactatccaa ggagacttca aagtgtatga ttcatgggaa
    11881 cagtccatgg atgaccatac acaactgttc gtccaaggag tagattggaa tcctgcgctg
    11941 tatgaaaaag tgattacggc caccaactat caggaagccg cacaagcatt gcaagatgca
    12001 ggttatgcga cagaccccgg ttatgcgcaa aaaatcatcc aggtcatcga gacgtatcaa
    12061 ttgaatcagt atgaccggag atagcaaagg agaagtggct gatggcagaa caatttacgc
    12121 cagaaatcat gacggaattg agaaaagata tcgtaagagt accggaaatc attttagaag
    12181 caagcgggat caagatattt ggaaaattga tccgttcgat catctttact acggatattg
    12241 cgatcatacg taatacaaat gcgaatgcag taattgctgt gtatcctttt acacctcatc
    12301 cagcgattac taaaagcatt attgaggcag ctgacattcc agttttctcc ggtgtaggtg
    12361 gtggtttgac acaaggtgct cgttcttcct acatgagcat gttcgcagaa gcgcaaggtt
    12421 cgttaggggt cgttttgaac ggtcctacgc ctttagagac agtaaaagaa gtttgtcgag
    12481 tagttgatat tccagttatc agtacggtaa cgtcgaaata tacagaaata gatgaaaagt
    12541 tagcagctgg tatttcgatt atcaatatca gtgcaggtaa agaaactgca gaagcagtac
    12601 gccattttcg taaaaaatat cctgaacttc ctatcattgc gacaggtggt ccaacggaag
    12661 aaagtattgc tgagaccatt caagcaggag caaatgccat cacatatacg ccaccaagta
    12721 gcggagagct ttttagtcgt aaaatggaaa aatatcggga aactgagaaa aagaatcatg
    12781 aataacaggt gagaatcaaa agacgaggaa gagcagatag tggctcttcc tcgtcttttg
    12841 tactccagta ctatttgttc agaattcaaa aaaaagagaa atttttttgt ttttttacct
    12901 gtaatgtaca taagaagagt taaaaccttt tgttattatt agcattctaa caaaaaaatg
    12961 tcttgattta ttgaagcgct ttctatagaa tgaaaaacga ataaaaacta aaaaaggcac
    13021 ccgacaattt agtagcagct aaattgtcgg ggcttgaaaa gtcagcggga actgaccaat
    13081 caagttgcca tagtcaatgc ttgtgcatcg acgtgtatat tgtacctaat ttcatacaga
    13141 attactagtt atttttctgt tttttaggga agagcgcaca cgaagaagca tgcttattta
    13201 gctatgtcaa ggatattggg cagttgtctg atatcctttt ttctttgcgt aattatcctc
    13261 ccatcattga agcaagaagt gtttttagcg atgaaagaag aatcagcact atctaatttt
    13321 tcttgaaagt attgagttgt tcatcctagg cagaacgata aggcaagtct tggtttttat
    13381 tccccttgaa aaagatcgtt taataaatat gttctgtata aaaatacagt atattgaaaa
    13441 ataacaatgg aagtagaggt gcagagaatg aagaaaagaa tgagaatcat cttagcttta
    13501 agtgttatgt tattcttctt gacggcttgt gggcaagaag atgacaaaaa aatcacgctg
    13561 aacatggctt ggtggggttc gcaagtccga cacgatgcaa cagtaaaagt aatcgagctt
    13621 tatgaagaaa aaaatcccca tgtgacgatc gattatgaat tttatgatta tgaaggatat
    13681 tacacaaaat taggtacact agcagcatca gatgatatct gggacatttt ccaactgaac
    13741 aatcaatttc ctcaatacat caatcagatt gaaccattag atgaatatgt ggagcaaggg
    13801 ataattgata tttctaatgc agatgaatcc tatttagcaa cgacgactta cgacgggcaa
    13861 ttagttggac tgtctaacgg ggtgaattcg tttgcgattg cttacaataa aaatatattt
    13921 gaacaattaa atatccctga accagcttca aattggacat gggatgaatt tgaacaaatc
    13981 agctatcaaa tcactgaaga attaggaatc tatgctattt caagattcga agattttata
    14041 gctggctgta ttattcaaat accacaagtt gagaaaggat tgaattttta taatcgggaa
    14101 gatctatcta acagcttggg atttgaaaat ccagactatc taacagattt tttccagctg
    14161 cgtaaaaatc tggtagacaa aggggcccat ccagaaccag gtggtggagc tgcaagtacg
    14221 acggatctgt cttttcaggc ggttagggat agagaagcgg caatggtgtt tctatcaagt
    14281 aaccagttga cagaaatatt gtcaggggct cctgaagata tggagattca gttgattaat
    14341 ccacctcgca gaaaagcaga tggagaatct ggtatccctt tacgttcttc gcaaatgctg
    14401 agtatggcaa aaagctcagc ccataaagaa gaagctgcta agtttattga tttctttcaa
    14461 aacagtgaag aagccaatga aattttaaaa ggagaacgtg gtgtaccaat catgtcgaat
    14521 attcgagaac agctcgctcg tgcagatgat gcaactttgc aagcgacatt tgattattta
    14581 gaaatgattt ccgatatgga caacggcgaa gtgaatgtct ttgatagtgc tttgaatccg
    14641 gaaattcaag accaatacaa tcttttagtt gaaaaagtca tttatgaaga agtaacagca
    14701 gaagaagcag cagagagtct ttatgagttt gcgtcaaaca ttctaggata gcagcaggag
    14761 gaaggcatga aaaaagaaaa actaaaacgg ttcttggatc aagacaatgt ggtcggttac
    14821 gtatttgctt ctccattcat cctaggattt ctattgataa cagtgatacc gatgatcttg
    14881 tcactttatt attcgttcac cgattatcgt ttgggaaatc cagtctcatg gatcggcttg
    14941 gataattata taaagatgct gagtgatgcc cgttttttga actccatccg agtcactttt
    15001 ctctatgtat ttgcatctgt acctgtgaaa ctgatctttg gtctattgat tgcttatctt
    15061 ttaacgagga atatcaaagg aacgactttc tttcgttctt tgtattatgt gcctagtttg
    15121 atcggtggca gtatttctat cgctctagtt tggcgggagt tgttttctaa aaacgggtta
    15181 gtgaatattt tcctggaacg attaggcgca cctgcgcttt cctggtttag cgatcaaaaa
    15241 ctggtcatga tccctcttgt tttgatgtct gcttggcaat tcggttcggc aatgatcatc
    15301 tttgctgcag gtatcaaaga gatcccaggc tcgtattatg aagcggcaga gatcgatgga
    15361 gcgaacaaat ggcagacgtt ttacaagatc acgttacctc ttctttcgcc gatcattttg
    15421 tataacttgg ttatgcagac aatcgcggcg tttatgactt ttacgcaggc atttatcatt
    15481 acccaaggtg gtccgaatga tgccacgaac ttttatgctc tttatgtgta taaccaagct
    15541 ttttctttta attctatggg gtatgctagt gctatttcgt ggatcatgct gttgattatg
    15601 ggagctgtca cctttctgat tttcaaatca tcaaaaaaat gggtcgttgt gtgaatgaga
    15661 ggaggaagaa atgaataata cagtaacgaa atggtttcaa tacggtttta ttttgctatt
    15721 aggtctagtc atgatttatc cggtcttatg gatgatcgca ggttctttta aaacggatca
    15781 agagattatg agtggttcgc tgaatttgat tccagagact tttcaatggg aaaattacgc
    15841 aaaaggatgg gcggggtttg ctggaatttc attttttact ttctttagga attcgtttgt
    15901 catctctgca gtttcgacga tagggacagt tctgagctcg acttgtattg cttacgcatt
    15961 atcgagaatc gatttcaaag gaaaaagatt ctggttcgtc gtcatgttag taacgatgat
    16021 gattcctgca caagtgattt tgattccgca gtttattatt tacaatcggc tgaatttggt
    16081 tgggacgtat gtgccgctga ttttaccaca tttttttgga caagcatttt tcatttacca
    16141 gatcatgcaa ttcatggtca gcatccccaa agagttagat gaatcagcga ttattgacgg
    16201 atgcagcaag tatagtgtct ttaccaaaat tatttttcct ttgctgaaac cttcgatcat
    16261 cacgacgatc atcatccagt tttattggaa atgggacgac ttcatgggac cattgattta
    16321 tttaaacaag ccgagatctt acacggtatc gattgccatc aaattatttg cagacgctgg
    16381 atctagtacg acttacgcga gtatgtttgc gatgtctacg ttgtcgctgc taccggtttt
    16441 tctgattttc ttattcttca ataaatatct tgtccagggg atcagtacaa gcggtctgaa
    16501 gggctgaata tgaaaaagcc aatagaagag atgtttcttt acaagctcaa ctactatgtc
    16561 tgtcggattt ttttaaccag tcttatcagt aatgctcttt tcgctttagt tctaggatgt
    16621 ttgttcactt taggattagt gctgtctgct cgtgttgtct atctgattta ttttttgatg
    16681 atgtatcctt cttattatct atctgtccat tacttggcag aaaaaaaggt atgttggagg
    16741 aaaggaaaaa tcaaacggat gtgtttcatc attacgttgt ttcagctgtt tgtcattatt
    16801 tttgcagttg attggtattt attagtggga aagattggag cttggtatct gattcctttt
    16861 ctattgtgtc tgttgctttt tgtatcccat agttttttta gtacgctaat tgatatctgc
    16921 aaagaagata aagcagatag tcttgtttat ttgatcaaaa ggaatatctg gctgttgtca
    16981 aaaaacgtca aggggtttct gtggtattta tgccttttgt atggactgtt ctggtgtata
    17041 cagcatgatt ttttactcac tgcattactg tatccagggc tgccatttgt cacagtattt
    17101 tgcttaaaag aaaaggagaa tgactttaaa tgaagaaaaa atatgtacaa gtcggacttg
    17161 gtgggagagc gcgttttttt tatgaggcaa ttgcctctac gtatcatcaa acttgtgaac
    17221 tagtcggttt ttgtgatgta tctcaaacaa ggatggatta tgcaaatcgg atacttgtga
    17281 acaagtatgg acagaaaaaa gtaaagacat gtatgccatc acaatttgag caactactgg
    17341 atgacgtacg gccggctgaa gtcattatta cgtcagtaga tcgaacgcat catgattata
    17401 tcattcgtgc aatgaaaaaa ggatatgatg ttatttgcga aaaacctctg actatcgatg
    17461 aggaaaaagc tcaagaaata ataacggtcc aaaaacagac gggaagaagc ctgcgagtca
    17521 cttttaatta tcgttatgca ccgtatcaca cgaagataaa ggaactgata gaaagtgatg
    17581 tgattggtga tgtgttttct atccacttcg aatggctgtt aaatacgcaa cacggggcag
    17641 attatttcag aagatggcat cgaaataagc acaatagcgg cgggcttctt gttcataaat
    17701 ctacccatca ttttgatcta gtgaattttt ggttgaacag ccgtccccaa aaggtatttg
    17761 cattcggtgg attaaacttt tatgggatgc ataatgcgga gaaacgcgga gtagaaatat
    17821 tttacagtcg atgctatgga agcgaactag ctaaagctga tccatttgct atagacctgt
    17881 cagccaatga ggaattgcga gaaatgtatt tagaagcaga aaaagacagt ggatatattc
    17941 gtgaccgcag tgtattttcc gatgatatct ctattgaaga tacactaggc gtaacggtca
    18001 aatatgaaac tggtgcgatt ttgacgtatt cgctaaacgc gtatatgccg tgggaaggat
    18061 tcaatgtttc tttcaatggc agcaaaggac ggatcgaaat gaaagtgatc gaaaagtctt
    18121 acatcaatgc aggtggagat aaaaaggatg aaggagcagc cgttcttcag tccatccatg
    18181 tctatccgat gttcggtgag ccatatgagg taatcgtcga acaagaagcg ggcggacatg
    18241 gcggaggaga tccgcgttta ttagatgatc tatttggtga agaaaaagaa gaagatccgt
    18301 ggaatcgggc agcaactcac gtagatggta ttttgtcgat tttgacagga atcgcagcaa
    18361 atcattctat tgcttcagga aaagcagtag tgattgacga gcttgtcagc ttaaaagaat
    18421 aagaatagat ttacggaaat tacttcccgt agtttataaa atcttgcctt attgccgata
    18481 ggctgtcttt tgaacactat ttattcggaa aaaggggcta tgacatgctt tttgtcatgc
    18541 cttcttttta tgtgggctgc ttttttagat aggagaaaat aaaaataact atttaaaccc
    18601 gaacaaaaag gaataatgca ttaaaaatca ttagatttta caaaaaaata agtaaaccac
    18661 gttgtcagtt tcagaaagta gtgttagact gttttcaata tttgaaacaa cattttttat
    18721 tcaaatatgg caaactgcct tcacgtgcaa aacagttgca agaaaatgaa tttacactat
    18781 tattagtttt acatacctac ttatatatcg tcataatatg gatgacagtt tctagccagt
    18841 accgtaaatg ctggactata agtaaaagat tggctatttc acccttcttt tcttatgata
    18901 aagtggaggg tgtttttctt taacagaaac atagtaggtt tttgcacaaa agcggttatt
    18961 tcggtattaa taaatgataa aggagcaaat aaagtgaaag aattagttga acgtattcaa
    19021 aaagacggac gtatattagg cgagggcgta ttaaaagtcg acagcttcgt cactcaccaa
    19081 gtagaccctg tattgatgga acaaatggga aaacggtttg cagaagtatt taaagaacaa
    19141 ggaatcacga aagttgtgac cattgaagct tctgggatcg caccagcttt atttgctgca
    19201 agagaattag atgttccaat gatcttcgct agaaaagcaa aaagtttgac gatggatgaa
    19261 gaattattga cagcttctgt ttattctttt acgaaacaag tgacaagtac gatttctatt
    19321 tctcgtaaat ttttatcttc agaagacaaa gtattgatta tcgacgattt cttggcaaac
    19381 ggacaagcgg caaaaggatt gatcgaatta tgccagcaag ctggagcgca agtagaagga
    19441 atcgggatcg tcatcgaaaa gtctttccaa gatggacgtc agttacttga agaaatggga
    19501 ttgagagtcg tttctcttgc gcgtattgct tccttgacga atggacaagt tgagtttctt
    19561 gaggaggacg cataatcgtg gaaaaagaaa cacaaaatgg aaaagctgcg gttttagggc
    19621 tgcagcatct gctagcgatg tatgcaggag cagtagcggt gcctcttttg atcggtacag
    19681 gactaggctt taatcaagaa cagatgactt atttgatttc aattgatatc tttatgtgtg
    19741 gattagcgac attattgcaa ttgacagtta accgattttt cggaattggc ttgcctgtcg
    19801 ttttaggatg tgcgatccaa gcagtagctc cactgatctt gatcggaacc aatgaaggag
    19861 taggagctat ctacggatct attatcgctt ctgggatctt tgttgtgtta gtttctggtg
    19921 tcttttctaa aattaaaaaa ctattccctc ctatagtaac aggaacggtt atcaccgtta
    19981 ttggtttgac tttgattcct gtagcaatcg agaaaatggg tggaggtaat gcaacagcag
    20041 ctgattttgg tgacaaaaca aatctgctac ttgcatttgt gacgattctc ctaattgtag
    20101 gcgtgcaaat gctggcaaaa gggttcattc gttcaatcgc ggtattgatt ggtttagtcg
    20161 gaggaagcat cttagctgct ttcatgggaa tgattgatct gagcgcgatt ggagatgcgc
    20221 cgttgttcca tgttccacaa cccttttatt ttggtaaacc aactttcgac gtatggtcga
    20281 ttttactaat gatcatcatt tccatggtca gcatggtaga atcaacaggt gtatattttg
    20341 cacttggtga cattactggg aaaaatgttg gagaagaaga attgaaaaag ggatatcgtg
    20401 cagaaggact tgccgttatc ttaggcggta ttttcaatac attcccttat actggctttt
    20461 ctcaaaatgt cggattggtt caactttcgg gaatcaaaac aagaaaaccc atctatttct
    20521 ctgcattctt cttgattgtt ttaggattat tccctaaaat cggtgcgtta gcacaaatca
    20581 tccctgagcc ggtacttggt ggaggaatgt tagtcatgtt cgggatggtg gcagtccaag
    20641 gaatccgtat gctgttggaa gttgatttca gcaatgataa aaatctattg attgttgctg
    20701 tttctgttgg atttgggctg ggtttcaatg ttacgccgac attattcagt caaatgccgc
    20761 aaacattgca aatgttcact ggaaatggca tcgtaatgag tagcattacg gctatcatat
    20821 tgaatttgat ctttaatgga ttgaaaaaag atgaagaaat attggaagaa gccttcaaga
    20881 agtaatagag caaaagaaag gttgtgaaat cagcgttttg acctgattgt tagagaaaca
    20941 aacggaaaaa tagttcctcg tattttgccg tttgtttgag ctaataccga gggtcagctg
    21001 attgaacacc gttgaaggaa gaggtcgtga gcctgccgtt catctccgag tcacaaggaa
    21061 caatttcaaa aaaaagcttc tcatgtttgt tgaatattgt tccttgtgac cgaggagttg
    21121 gcaggagaac accgtttatc cataaaaagg aatgtgacct aacttttgtc acattccttt
    21181 tttttatctt taataaacac gaacaataaa atgtttttct ttgttaacat tcgaaatttc
    21241 tttgacatca aaaaaagtga ttgttaaaat atgaatgtag aaaaactggg aggaaaaaca
    21301 atgacagcaa aaatctctgt gattatgggg agtacttcag attgggaaac aatgaaagaa
    21361 gcatgtcaaa tattggatga attcggtgtg tcttatgaaa aaaaggtcgt ttctgctcat
    21421 cgaaccccag atttgatgtt tgaatatgca caaaacgctc gaaaaaaagg aatcaaaatc
    21481 attattgcag gagcaggggg agccgcgcat ctgccgggta tggtcgcatc aaaaacaact
    21541 ttgccggtta tcggtgtacc ggtccaatca cgaacattaa atggtttgga ttcgcttctt
    21601 tcgattgtcc aaatgcctgg aggagtacct gtagctacta cagcaatcgg aaaagcggga
    21661 gcaattaatg ctggactact tgcgatacag atgctttcca tgtatgattt agaattggag
    21721 gctaaattgg ctgaaagacg ttcaatgttg gctaaaactg ttatagaaag tagtgatcaa
    21781 cttggttaaa cctttgttgc ctggttcaac gatcgggatc gtcggtggcg gtcaattagg
    21841 tcgtatgatg gcgattagtg caaaagaaat gggctttaaa gtaggtgtgc tggatcctgt
    21901 gagcgattgt ccagccgcac aagttgcaga ttggcacatt gaaagtgtct atgatgacac
    21961 ctttgcgctg aaagagcttg ccagaagaac agatgtcatt acctatgaat tcgaaaacgt
    22021 cagtgtagag gcgttaaatg cgattttacc catgtcattt attcctcaag ggacagactt
    22081 gcttgcgatt acgcaagacc gcctgttaga aaaatctttt ttggaaacga ataacatcgt
    22141 gattgctcct tatgcaacga tcgtcagtcc gacggatatc caagatgcga ttgacgggat
    22201 cggctatcct tgtgttttga aaaccactcg aggcggctat gatggcaagg ggcagtatgt
    22261 tttgaaaagt cgggcggatc tagctcctgc catggacctt ttaagagaag gaacctgtgt
    22321 tttagaagca tggatcccgt ttgaaaaaga gatttcgatc atggtggcag gaaatggtca
    22381 aggagatttc acgacttttc cggtcgtgga aaacatccac cacaacaata ttcttcatga
    22441 aacgattgct ccagccgcga ttgatcagga tgtgatcgag gaggctgagc gtattgcccg
    22501 tgtgattgca gaagcagtga gcctttcagg tgttttaggg gtagaaatgt ttttaacaaa
    22561 aacaggcggg ctatatgtga atgaattagc tcctcgtcct cacaattctg gacattattc
    22621 tattgaagct tgttctatga gtcagttcga tgcccatatt cgaggtattt gtggttggcc
    22681 attaggagaa aaagtacgtt tgataagcaa tgcagtaatg gtcaatgttt tgggagaaca
    22741 actgctggaa agctatcgct tgattgagaa taagccagac tggcaattcc atttctatgg
    22801 aaaaaaacaa gcaaaaaaag gtcgcaagat gggacatatc actatcttga cagaagacat
    22861 ccagcaaacg ctggaagaaa tcaaacaaac gaatatttgg gattagagga gaaaaaacat
    22921 gttagaacgt tatacacgcc ctgaaatggg gaatatctgg acggaagaga acaaataccg
    22981 tgcgtggctc gaagtcgaga ttttagcaga tgaagcttgg gcagaacttg gtgaaatccc
    23041 gcaagaagat gtgaaaaaaa ttcgtgagca tgcatcattt gatatcgatc ggatcttgga
    23101 aatcgaaaaa ttaacacgcc atgatgtcgt tgcgtttaca cgagcggttt ctgaaacatt
    23161 gggagaagaa agaaaatggg tccattatgg tctaacaagt acggatgtcg tagatactgc
    23221 ttatggctat ctcatcaagc aagcaaatga tattttacgg gaagacttga aacgttttac
    23281 ggaaatcatt ggcgaaaaag caaaagaaca caaatataca gtgatgatgg gtcggacaca
    23341 cggtgtccat gctgaaccaa ctacttttgg attgaaactt gccacatggt attcagaaat
    23401 gaaacggaac atcgaacgat ttgaacatgc ggcaaaagga gtagaagcag gaaaaatctc
    23461 aggagcagtg ggaacgttcg caaatatccc gccatttatt gaagagtatg tatgtaaaca
    23521 attggggatc cgtccacaag aaatctctac tcaagttctc cctcgggatc tacatgctga
    23581 atatttctca gcgatggcgc ttattgctac aagtattgaa cgttttgcaa cagagatacg
    23641 cggattgcaa aaatccgaaa cacgtgaagt agaagaattt tttgcgaaag gtcaaaaagg
    23701 ttcttctgct atgccgcaca aaaggaatcc gatcggttca gaaaatatgg ctggtctagc
    23761 cagagtggtg cgcggacaca tggtcactgc ctatgaaaat gtcacattat ggcatgaaag
    23821 agatatttct cattcttcag cagaacgaat catcttgcct gataccacga ttttattgaa
    23881 ttacatgtta aatcgttttg gcaatatcgt taaaaatcta acggtctttc ctgaaaacat
    23941 gaagcggaat atgtctgcaa catttggttt gatttatagc cagcgcgtta tgctgaaatt
    24001 gatcgataag ggaatgacaa gagaagaagc ttatgatctt gttcagccaa aaactgcgta
    24061 cgcttgggac aaccaagtgc agttccgccc gctgttagaa gaagatccaa ccatcacatc
    24121 ggtattatct aaagaagaaa tagacgatgc ctttgattat catcatcatt tgaaaaacgt
    24181 tgacgtgata ttcaaacgag taggtttgga ataaagaaga gtgagttgca aaattcaatt
    24241 aaaatagaat agcaaaaata atcgagtaga ggggaaagcc aactgacctt ccgcccctct
    24301 cacaccaccg tacgtacgga cccgtatacg gcggttcaat aagttgagtg tacgaactgg
    24361 tacttcaagg agatgtcctc atatccttgg cgggccagtt ctttgtctgt taatgatcga
    24421 tgaagaatat gacttttgga gactgaccaa ataccttttc ttgtatttga ccattcatac
    24481 gctttcgctt tatcgatccc taaacgaatc agattttttc ttttggttct tggattcttc
    24541 cattgtttcc aaatatattg tctgattctt cgcttcaacc aaccgtttaa ctccctcatg
    24601 aattctttca tctcaccaat tccatagtag ttgatccaac cagtcattag ttgcttgatt
    24661 tcttttaaaa taagttggat acttcttcca cggtttcttt tagtgagttg tttgagcttg
    24721 cttttcacac gctgttttgc ttttgcgtga gggcgaattt taataccttt ctttgttggc
    24781 agaatgcaga atccaagaaa ctttcgtttc aatggacttc ctaccgcact cttttctcga
    24841 tttaccgtca actttagttg ttcttcgaga aattgaatgg atttcttcat cacacgctgt
    24901 cctgctcgtt tgcttctaac atagatattg cagtcatcgg cgtatcgaac aaatttatgt
    24961 cctagatttt ctagcacttg atcaaattcg ttcaggtaga tgttacttaa caggggagag
    25021 agattgcctc cttggggcgt tccttcttca gttgttgtga tgagtccatt ttccattaca
    25081 ccactcatta agtattgacg gatcagtttt aggacttgtt tgtcctttac tttccgctca
    25141 atgaaataca tcagcttatc gtgatttacg gtgtcaaagt aggctttcat atcaatgtcc
    25201 accacatatc ggtaaccttg ttcataataa gattttgctt tcttcactgc gtcatgtgcg
    25261 ctgcgatttg ggcgaaaccc ataactatta tctgagaatt ctggttcaaa tagcggttgt
    25321 aacacttgat tgattgcctg ttgaagcata cgatcaataa ccgtgggaat tcctagtttt
    25381 cttacaccgc cgtttggttt cggtatttct actcgcaaaa caggctgagg tttatagttc
    25441 ccttggcgta aattggatag taattcctcg cggtgctctt tcaagtaagg aagcagttga
    25501 tcgacggtca tcccatctgc accagccgcc cctttatttc tgactacttg aagatacgct
    25561 tgattgagat tattccgatc tagaattctc ccaaacagat tttctacacc atcttgtttc
    25621 ctctgttcac cgcaagaagt gctgcgcact tcatcatacc cttcgtgttc cacactagct
    25681 ctttgatgat agccaagttt tcttgttttc tgcggtcgtc gcatcttctc acacctccta
    25741 aattattcaa gattcttatt gttcagtcct tcgtaacggt cagtgtcgtt actactatga
    25801 cctcggctga cttctcatga ttcaccatca tgtcgccatg atcgttgtgc tggtttgttt
    25861 tcattcaacg cccacaacac cctcatgaga tctcccccgg taagagtgaa aactttcctc
    25921 ccatgtaact gctagattta ctgtataggt ttcgggcagt attggacttt gtcttgtgat
    25981 gaagacttat ccgacctaat tcagccttgt atctagtttc tgttcgtcag ttcaggagtt
    26041 tgcgtccgac ttccttcagc cacaacctca cgattgccgc cttgtctttc gctaacagtt
    26101 cctactgcca agcctgtagt ggactttcac caccaagttt tcacccatgc agggcgcaca
    26161 ccaaaaaaga agcagatccg ttagcggttc tgcttctttt agtttattat attttcttat
    26221 caataatagg aacctgattt taaaagcggc tacctcttta ccgtgcctct ttacatacaa
    26281 aaaatagagg aattaagcgt aaatggcttg gctattataa ctaaaatgct ggttatggag
    26341 atgttgcagc aagttttcga gaaaagcgta ttccatctct tgtccattga ataagatctg
    26401 gatacgataa tgatttttga aacgcttctg ttcatgaatc tgactgattg aaagttcgcc
    26461 tttgtgttct gtctgataaa gaaaagtcct tttacggcat tcagcacagc gcttggttgc
    26521 tcggcggatt tttcggaatg tataaaaact agtatcttta ttgcataaat aaacgtcttt
    26581 gatcgacagc aaatcattat atagacagga acgttcttca gctgttaatt ctgataaaaa
    26641 aagctgacct tgttttattg catcttccat cggcaagtgc ctcctcgaac ccattatcca
    26701 aatttttagt taattctaat ataccatcat taagtataaa tgtaaacgct tgttgatggt
    26761 ataagatttt cgtttctgat aaaacacgaa cattaaaaga atctaatgcc ttaaatgtac
    26821 atatttttgt tgatttataa aaagatgatt gctaaaattt aaagtgaaaa aacgaacaaa
    26881 aaacgatgta tttgctttta atgtaaataa aaaggagaga cgtacatgga gaagaaagaa
    26941 cttttgtatg aaggaaaagc caaaaaaata tatcttactt ctgatgagaa cttgatttgg
    27001 atagaatatt tagatcaagc aactgcgttg aatggcgcga ggaaagacca gataagtgga
    27061 aaaggagaat tgaataatca aatcacaagt gcaattttcc gttatctgac tcaaagagga
    27121 ataaaaaatc attttattga acaattgtct aaaaccgaac aattagcaaa aaaagtacaa
    27181 attatccctc tggaagtggt tatccgaaat attgcagcag gaagtttctc aaaacgtcta
    27241 ggtgttcccg aaggtaaaga attcatcaaa ccaatcattg aattctacta taaggatgac
    27301 cagttggatg atccatttat caatgaagag catatctatt tcttacaact tgcaaagccg
    27361 gaagaaatca gtgagctgaa agcccaagcg ttggctatta atgaaatttt gaccgaatta
    27421 tttgctaagg tcggtttggt tttagtagat ttcaagctag aatttggccg gtcgaatgga
    27481 caaattttgc ttgcggatga agtaacaccg gatacttgcc gattatggga tgaacgtacg
    27541 aatgaacata tggacaaaga cgtttaccgc agagatctag gtgatttgat cccagtctat
    27601 caagaagtat ataaccgtct atcggaacta actgaagaaa aggagcgagt atgatgtatt
    27661 tcgtaaaagt atatgtaacc tataaagatt cagtgttaga tcctcaaggg gaggcagtaa
    27721 aaaaagcagt ccatcgtatg ggatatgaaa caatcgaaga tatccgaata ggaaaatact
    27781 ttgagataca acttgctgat gcagaagaac caatcgatac agtgattgaa acgatttgtg
    27841 acaagctgct tgcaaatgta aatatggaaa cataccgata tgaaatcaaa aaaatggagg
    27901 aagtataaca tgaaatttgc ggtcatcgtt tttccaggtt caaattgtga cgcagatatg
    27961 ttatgggcag ttcgcgagat catgggcgct gatgccgaat ttgtacggca tgatgagtcc
    28021 tctttagaag gatttgatgg ggttttactg ccgggaggat tctcctatgg tgactatttg
    28081 agatgcggtg cgattgctcg gttttctaca atcatggaag aagtgattcg ttttgctgaa
    28141 gaagggaaac cagtattcgg tacatgcaat ggattccaga tattgacaga agcaggactt
    28201 ttgccaggtg tactgagacg aaatgagtct ttgcatttta tttgcaaaac tgtaccattg
    28261 aaagtcaacc ccaagacggc ctttacttca gagtatgaag ccgacgaaat aatctatctt
    28321 ccagttgctc atggggaagg aaattatttc tgtgacgaag aaacacttca agaactaaaa
    28381 aaaaataatc agattgcctt tacttataat gacaacatca acggcagcgt ggaaaacatt
    28441 gcagggatta cgaacaaagc agggaatgtg ttaggaatga tgcctcatcc agaacgtgca
    28501 gtagaagact tgctaggatc agaagatggg aaacggttct ttgcttccat tttaaaaaac
    28561 ttcggaaagg tgaccgtata gatgaaaaca ttgaaagaac cgacagctga agagatcaag
    28621 aaaaaaagaa tctatgccga atggggattg actgatgaag aatatcgaat gatcgaagaa
    28681 gatatcttag gaagaatgcc taattatacg gaaactggac tgttttctgt tatgtggagc
    28741 gaacattgtt cctataaaaa ttctaaaccg gttctacgca aatttcctac tagtggacct
    28801 catgtgttgc aaggccctgg agaaggcgca ggcatcgtcg acatcggtga tggactagca
    28861 gttgtcttca aagcagaaag tcacaatcat ccttcagccg tggagcctta tgaaggagct
    28921 gcgacaggag ttggcggaat catcagagat attttcagca tgggggctcg tccaattgcg
    28981 ttgctagatt cattgaggtt cggcgaatta gataatccaa gaacgaaata tttactagaa
    29041 gaagtagttg caggtatcgg cggatacggc aattgtatcg gcataccgac tgtaggcggc
    29101 gaaattgcat ttgatccttg ttatgaagga aacccattag tcaatgcaat gtgcgtaggt
    29161 ttgattgaac acaaacatat ccagaaaggg caagccgctg gcgtcggtaa ttcgatcatg
    29221 tatgtaggtg caaaaacagg tcgcgacggt atccacggag caacttttgc ctcagaagaa
    29281 tttaatcaag aagaagaaca gcaacgttct gctgtacaag taggcgatcc ttttatggaa
    29341 aagctgctgc ttgaagcgtg tttggaatta atcttgcatc attcggattc tctaataggt
    29401 atacaggata tgggagcagc aggacttgtt tcatctagtg cggaaatggc ttcaaaagct
    29461 ggctcaggac ttatattgac attagatgaa gtcccacaaa gagaaactgg gatgacacct
    29521 tatgaaatga tgttatcgga atcacaagaa cggatgttga tttgtgttaa atcaggagag
    29581 gaagaaaaaa tccaagaact atttcagaag tatgatctag atgcagtcac tatcggtaaa
    29641 gtaacagacg acgggcaata tcggctatat catcaaggag aagaagtagc aaatctgcca
    29701 gtcgatgcat tagctgaaga tgcaccagtt tatcataaag aaatgaaaga accagctcga
    29761 atcgtagaat ttcagcagtt agctccttat cagccagtta tcgaagaacc tggacaagta
    29821 ttgcttgatc tgctgcagca accgacgatt gcttcaaaac gttcaatcta cgaaacttat
    29881 gattcacaag tacaaaccaa tacagttgtc cgtccaggaa gcgatgctgc tgtgatgagg
    29941 gttagaggga cgaataaagc gttagctatg accacagact gcaacgcgcg ctatctgtat
    30001 ttggatccaa aaatcggagg acaaatagca gtggcagaag ctgctagaaa tattattgct
    30061 agcggtggta agcccttggc gatcaccgac tgcctgaact atggttctcc tgataaacca
    30121 gaagtttttt gggaattatc gacttcagct gacggaattg ctgctgcgtg tgaaacgtta
    30181 ggaactcctg ttatttcagg aaatgtctct ttatataatg aaacggatgg tcaagcaatc
    30241 tatccaacac caatgattgg tatggtcgga ttgattgagg atcataaaca tatcactact
    30301 caggaattca aaaaatcagg ggatctaatc tatatattag gtaagacgtt tgcagatttt
    30361 gatggcagtg aattacaaaa gatgcagctt ggaagaatcg aaggtgtgat ccgaaacttt
    30421 gatctatcca ttgaaaagag aaaccaagag ttagtattga cagccatcca aaacggattg
    30481 attgaaagtg ctcatgactg ttcagaaggt ggcttggcaa ttgcactggc agaatcagct
    30541 ttcaaacatc agctagggat atctgtacag tttgaattgt cctctgctca attatttgca
    30601 gaaactcaat caagatttgt gttgacagtc gcaccggaaa ataagacacg attcgaagaa
    30661 atgatgggag atgctgctgt tttagcaggt aaggtgacgg atgaagcgat aatcgaaatt
    30721 tcagcaactg acggtcagat caaaatagaa actgcagtag caagaaagtg ctgggaggat
    30781 gcaatcgtat gtcttatgaa gtgaagagtt taaatgaaga atgcgggatc ttcggtgttt
    30841 ggggtcatcc agacgccgct agtgtggcat acttcgggct ccatagtctt cagcatcgag
    30901 gacaagaagg tgcaggtatc gtgtccaatg atcgaggaaa gcttaagggg catcgagatt
    30961 tggggctgct ttctgaggta ttcaaagatc aaagaaaatt gcagcagtta acaggagaag
    31021 ctgcaatcgg acatgtacgt tatgcaacag caggcaatgg aagtgtggac aatattcagc
    31081 cttttctatt caaatttcat gatcagtcga tcggcttagc gcataatggt aacttgatca
    31141 atgctcgttc ccttagaaaa gagttagagg aaaatggggc gatcttccat tctaactccg
    31201 atacggagat attgatgcat ttgatccgac gaagtgaaga aacagatttt ttaaataaat
    31261 taaaaagtgc tttgaatgaa gtcaaaggtg gctttgccta tttattaatg acagaaacgg
    31321 caatgattgc cgctttggac ccaaatggtt ttcgtccatt agcaatcgga caaatgaaaa
    31381 acggagcata cgtgattgcc tcggaaactt gtgcattaga agttattggg gcacgtttta
    31441 taagagatgt ccagcctggt gagatagtga tcatcaatga cgaaggaatc cagattgatt
    31501 gctttacgaa ggacacgcag ctttctattt gttcgatgga atatatctat tttgccagac
    31561 cagattcaaa catcgcaggg atcaatgtgc atactgcacg gaaaaatatg ggacggaatt
    31621 tagcgaaaga atcgccagta aaagcagata tggtcgttgg cgtacctaat tcttctttgt
    31681 cagccgcaag cggttatgcg gaagctagtg gaatccctta tgaaatcgga ttagtaaaaa
    31741 atcaatacat tgcccgaaca tttatccagc caacgcctga gctaagagag caaggtgttc
    31801 gaatgaaatt atctgctgta cgaggagtag tggaaggtaa aaaggtgatt atggtcgatg
    31861 attcaattgt tcggggtacg acaagcagac ggatcgtcca tcttttgaaa gaagcagggg
    31921 caaaagaagt ccatgtgagg attgcttctc ctcctttgaa atatccatgt ttttacggga
    31981 ttgatattca aacgcgtaaa gaactcattg cggcaaatca cacgattgat gaaatcaaag
    32041 aatgtatcgg tgcagattct ttaggttttt taagtgaaga gggtctgatc gaatcgatcg
    32101 gtctggaaaa agatgctccg tattcaggat tgtgtatggc ttatttcaac ggagattatc
    32161 cgacgccgtt atatgactat gaagaaaaat atcaggaatc actaaaagaa aaagtatcgt
    32221 tcttttaaaa gcagaccaag aagggagtat atgaattcaa tggcaaatgc atacgcaaaa
    32281 gctggcgtag atgtcgaagc tggatatgaa gtagtagaac ggatcaagaa gcatgtcaaa
    32341 aaaacggaac gtttaggtat gatgggcgct ataggaggat tcggcggttg ttttgattta
    32401 tcggtctttc aattaaaaga gccagtcctt gtctcgggga ccgatggcgt ggggacgaaa
    32461 ttagcagtgg caatcgaagc agacaaacac gatacaatcg ggatcgactg cgtagcgatg
    32521 tgtgtcaatg atatcttagc acaaggcgca gagccgttat atttcttaga ctacttagca
    32581 acggggaaaa atgatccgtt acgtttggaa aatgtagtaa aaggtgtagc agatggatgt
    32641 gttcaaggaa atatggcgct gattggcgga gaaacagctg aaatgcctgg tatgtactca
    32701 ggtaatgatt atgatctagc cggatttgct gtagggatag ctgaaaaatc tcaattattg
    32761 acaggagaaa cgatcaaccc aggagatgtg ttgcttggaa tagcatctag cgggattcat
    32821 tcaaatgggt actctcttgt tcgcaaaatt ttctttgagc agcagcagtt ttctttatca
    32881 tcaaaactgc cagaattgaa aaaaacactt ggcgaagaat tgcttgagcc aacgaaaatc
    32941 tatgtttctt ccttgcttcc gctgatcaaa gaaaagaaaa taaaaggagc tgcacatatc
    33001 actggtggag ggtttgtaga aaatatcccg cgaatgttac cagaatctat ggctgcacaa
    33061 atcaaacttg gctcatggcc gattcttcca atattcggct gtttacaaaa atatggtgaa
    33121 attcctgaga tggagatgta tgaaatcttc aatatgggca tcggtatggt cctggcagtc
    33181 caagaatcga aagtaaaaga aatagtacac gaaattgagc aagctggcga aaaagtttat
    33241 gaaatcggga aagtgatcgc caaagaaaaa catcgtgtgg tgtttatagg agaagaacga
    33301 tgagaatcgc tgtttttgct tctggaaacg gaagcaactt tcaagcgcta gccgattatc
    33361 tatcgaaaaa aggattggaa tcttcgattg actggttgtt ttgtgatcag cctgaagcat
    33421 atgttttgaa acgtgcaact gcgttgagtg taccggcaga ttgtttttca cctaaagaat
    33481 ttgattcaaa aaaagagtat gaagaagcaa ttttgcataa attgaaagaa aaaaagatcg
    33541 atttgatcgt attagctgga tatatgcgaa tcattggacc ggtattgctg aaaaattatg
    33601 ataaaagaat catcaatatc catccgtctc ttttacctgc cttccctggt ttgcatggca
    33661 tacgtgatgc ctttgaagct ggagtaaaag aaacgggtgt cacaattcat tatatcgacc
    33721 aaggtgtaga tactggacca atcatccggc aggaaaaagt gagaattgaa caggaggaca
    33781 cgttcgattc tttagaagaa aaaatccata gagtagagca tcgaatctat ccagaagtga
    33841 ttagtgaaat tattgaaaat ggaggctatc tgaaatgaca agagcattga tcagtgtatc
    33901 agataaaact gggattgtag cattcgccca aggtttgatt gaacaaggag tagaaatcat
    33961 ttcaacagga ggaacaaagc atgcgttgga taaagctggg atcaaaacgc tttcgatcga
    34021 agaagtgaca gggtttcctg aaatgatgga tggccgtgtc aaaacacttc atcctaaaat
    34081 ccatggtggt cttttaggaa gacgcgatct ccctagccat atggaggcaa tggaaacgga
    34141 aaatatccaa ccaatcgact ttgtttgtgt caatttatat cctttcaaag aaacgattat
    34201 gaaaccagat gtcgaaatag cagaagctat tgaaaacatt gatatcggtg gtcctagtat
    34261 gctccgtagt gcagcaaaaa accatgaatt tgtcacctct gttgttgatc catctgacta
    34321 tgaagaagta ctttcagaat tacgtcagta tgggcatact tcactttctt tcagacaaaa
    34381 actagcggca aaagtctttc gtcatactgc ggcatatgat gcactgatcg ctcaatactt
    34441 aacggattgg gtggaagaaa aagaaccgga aaaattgaca cttacgtatg aacgaaaaca
    34501 aacgcttcgt tacggtgaaa atagccatca agccgctgcc ttttatcagt ccgctcttct
    34561 ggaaaaatat tcgatcgcag cagcaaaaca actccatggg aaagaacttt cttataataa
    34621 tatccgagat gcagatgctg cgctacggat catgaaggaa tatgacgagc caacggtagt
    34681 cgccttgaaa cacatgaatc cttgtggtat tgggacagca tctacgattt tagaagcgtg
    34741 ggaagcagcg tatgaagcag atcctgtttc aatctttggt gggatcatcg ttttgaatcg
    34801 agaagtagat ctgccaacag cagaacagat gcataagctg tttctagaaa tcatcattgc
    34861 cccttcttat acacaagaag ctttggaatt actgcaaaaa aagaaaaaca tccgattact
    34921 gacagtagac tttgcgcagg aagaaaatca aaatcgagaa gaaacggtct cagtcttagg
    34981 tggacttctt gtacaagatc aagatctggc aatagaaaat gaagaagagt ggaaagtcgt
    35041 gacaaaacgt aagccgactc cagcagaagc aaaagcatta gcgtttgctt ggagagctgt
    35101 caaacatgtg aaatctaatg cgatcgtact ggcaaacgaa cgtcagacag taggaatcgg
    35161 agccgggcag atgaatcgag tcggttcagt aaaaattgcg attgaacaag cgcaagagaa
    35221 aatggaaggt gcagttttag ctagcgatgc ttattttcca atggatgatt cggttgaata
    35281 tgcagccaaa catggtataa aagcaatcat tcagccagga ggaagcatca aagaccaaga
    35341 ttctattgat atggcgaata aatacgatct agcaatggtc tttactgatg ttcggcattt
    35401 tagacattag agaggagtcg gataaatgaa cattttggtg atcggtgcag gtggtcgtga
    35461 acatgcaata agtaaaaaac ttttagccag tccgaaggtg gatacggtgt attgtgcgcc
    35521 aggaaatccg gggatgacaa aagatggtat caattgtgtc gctatcagtg agcgagatca
    35581 ttcagcgtta atccattttg ttaagaaaga ggctattgat tggagtatcg ttggtcctga
    35641 agttcctttg ttaaatggga tcgtcgatga ttttatggcg gaaggattga aaatcttcgg
    35701 tccgacaaaa gcagcagctc tgatcgaagg ttcgaaaagt tttgctaaac aattaatgga
    35761 tacttatcaa atcccgacag ctaaatccag aagttttgaa tgttacgaaa aagcagcagc
    35821 gtatatcaaa gaaaatggtg cgccaatcgt agtgaaagcg gacggcttag cagctgggaa
    35881 aggtgtagtc gtggctacca cagtgaagga agcgctggat gcggcagaac aaatgttgaa
    35941 ccagcatcga tttggggata gtagcaaaaa aatcgtcgta gaagagtttt tggcaggaga
    36001 agaattctcc cttttggcgt ttgtccgtaa taccaaggtg tatccgatgg tcatttcgca
    36061 agatcataag cgggcatttg ataacgataa agggccaaat acaggcggaa tgggtgctta
    36121 ttcaccagta ccgcaaattt caaaaaagat gattgaaaaa gctgtggaag aagttttaaa
    36181 accagcggct ttgggaatga aagaactagg acgctctttc acgggtgttt tatatgcggg
    36241 tttgattgct acgaaggaag gaccaaaagt gatcgaattc aatgcgcgtt tcggtgatcc
    36301 tgaaacgcaa gtcgttcttt ctcggttgaa gagtgacttt gcgcaagtaa tcgatgattt
    36361 attagagaat cgtacagtag agttaaagtg gcagcaagaa ggatacaatg taggcgttgt
    36421 ggttgcagct gccggttacc ccgaagaata tgagacagga atggttctac cagattttct
    36481 ggaagaagag ctttctgttt actatgctgg agtttcctca aataacggca aactagttgg
    36541 agcaggagga cgtctttatt tagtagaagc atacggtgag acgatcaaag aagcacagaa
    36601 aaaaatttac accgcgttaa tggataaaac gacagatgga acattttatc gtacagatat
    36661 tggagaaaaa gctgccaata gcgaactgat cgtgaagtaa atcagctgct tccatttata
    36721 aaaaatacaa caaacataat cggaagcgcc gattttagtg aagccttttc ataaagagtg
    36781 tggtacactt ttgttgtgta tataaataag gaggagttca gatgaaaaaa attcaattag
    36841 gtacttctga tcagaaagca gctgcagtga tcttaggctg tatgcgtatc aacaatgcgg
    36901 aagatccagt aaaagtgatt gagacagctt atgaaaacgg cattgatttt tttgaccatg
    36961 cagatattta tggaaacggt gaatgtgaag aaatctttgc agatgctcta gcaaaaacat
    37021 caatcaaacg agaagatctt tttattcaaa caaaatgtgg aatcgttcca ggtgtgatgt
    37081 ttgatttttc taaaaaacat atcattgaat ctgtagaaaa aagtttgacc cgtctgaaaa
    37141 tggattatgt ggatgcttta cttcttcatc gtccagatac attggtagaa ccagaggaag
    37201 tagctgaagc gtttgatgaa ttggaacggt caggaaaagt tcgttatttt ggcgtcagca
    37261 atcaaaaacc aatgcaaatc gaattgctga aaaaatatgt tcgtcaacca ttagtagcta
    37321 atcagctgca atttggcttg aaacatactg gaatgatcga tcaagggatt catgtcaata
    37381 tgacagatga agcaagtatc gatcatgacg gtagtgtact tgattattcc cgattgcatg
    37441 atatgacgat ccaagcatgg tcaccatacc agtatggatt ttttgaaggt gtatttatcg
    37501 ggaacgaaaa attccctgaa ttaaaccaaa cattagaaga actagcagct aaatatcaaa
    37561 cgacaccaac tggcttggct tctgcttgga ttttacgcca tccagccaat atgcaagtga
    37621 tcgccggtac gatgaacgta gggcgaatca aggaaatcgc tcaagcttca gaaattaata
    37681 tgtctcggga agattggtac gaattgtacc gtgctgctgg aaacatttta ccttaaagat
    37741 tgtcataagc aggtcaaaag ggctataaat taaaaagaca gaataacttg aaagctgttt
    37801 tcagcttcga gatattctgt ctttttttat tgcaaatgga aagagtatca ttgtacggat
    37861 ttcgtttatt agttattttt gtttttaagg aaaagctgtg tccgatattc ttttggagaa
    37921 atcccttgtt ttttcttaaa taaataactg aaatagttag ggtcattata accaatttca
    37981 aaagcaatat ctgaaatacg atagtctgat tgctgcaata atttttttgc taattcgatt
    38041 ctttgttctg tcagataatc gatgaatgtt tggttaaacg attgagaaaa aatcgtactg
    38101 aaatgagagg gacttaatgc aacttgttga gcgacccaag ttaaggacat atctggatcg
    38161 gtaaaatttt ctttgataaa atccaatgca tggttcaaaa ttggctgata tttgttcctt
    38221 gaaggctgtg agggcagagc agttaagaaa gaaatgaaca tataaactgt cgaacggtaa
    38281 agcgagtcgt cggcgctgat tgctaagcgt tgactggtgg atgtgcaatg aaccatttct
    38341 tgcgggattt tcttttcttt caggcagaca tgctggagta gcttagtcaa gacaaataaa
    38401 cgatataatc gtgttcgagt tggtgtgcct tgtggtttcg tcaagtgttc gatgtactta
    38461 gatacttcgt ttttcgataa tgaagacaaa tcaagtgaga ggtcaaagta aaagacagaa
    38521 tcaactggaa gtttcgcttc ttgaatcaaa tcctcatagc tgataatttg ttctttaagg
    38581 gaactggcgg tttcaagtat catctgcgtg atctcaaaag atgcaggtaa ttcgctgatt
    38641 ctttctgcga caggaccaat ggcgacagaa aaattatttt tttgtccctt ttctaattca
    38701 tggaccaacg tttgggctac ctgataactg gtctcgatca cattttcttc aagagaatca
    38761 actattaaaa atttgatgaa tcgagaggaa acagcagaga agatcacttg ttgattctcc
    38821 ctaaataaaa acttcaaata atcactgaga tgagcgtaat cttcaaagtc tgtactgact
    38881 tggtttgctg ctaataatac ggtcattttt ttccctgcta aagagcgatt gaaagattca
    38941 gcaagtttca atgtttcact gatcgtaagt gagcctttga acaaaccgtt caagaaatga
    39001 ttttttttca attcgaaaac aagatcagaa gaagtgtgcg tttctttttg ctgcaaatct
    39061 aaagcagtta ctgctttttc tattgcttgt ttcaattcgc tacttttaat cggtttaagc
    39121 agataatcat ctgcctgtac ctggattgct cctttcatat aatcgaaatc gtcgaatcca
    39181 ctaataaata tgagacgagt ccaaggaagt agtttccttg cttcttttga aaaagtcaac
    39241 ccgtccatga aaggcatttg gatatcagtc agaatgatgt cgggctgtaa gtcgataatt
    39301 gaagacagtg ccatctcacc atctccagct tcgccgacat aagtgattgg ataataagaa
    39361 ccaaggacag ttatttgttc ccgcaagtta ttgcgaatga ggtattcgtc ttcgatgata
    39421 aaaactttat acatgtttgt ttcctccaat tgttttggga gatagaggga tcatcagtgt
    39481 gacagttgtt ccttctcggt atttgctgtc aatcgtgata ggtttttgat catttccgta
    39541 ataaagaagg agacgcttgt ttacgttgta aagtccgtag ccgatactga aatctgaatc
    39601 gatccctttg gctaactctt tacgtatttc tgccagtttt tctgcaggga tgccaatccc
    39661 gttgtctata actttgaatt ggatcatctc atcaattttg catgtggtaa tacgaataaa
    39721 tcctttgtga cggacgtact tcgttccatg gtatacagca ttttcaatca atggctgcaa
    39781 gatcattttt aaaatagaaa caggaaaaag tgtttctggt atatcgatct tatagtcaag
    39841 catatggccg tatcttattt ttaagatgac tagataatca ttgatatggc taatttcttt
    39901 ttcaagagga atccagtctt gtcctttgct taaagacgta cgaaaaaagc cggaaagtgc
    39961 atgggtcata gtcagagctt cttcaaagca gtcttgttcg atcaaagaaa taatggcatc
    40021 caaactgtta taaataaaat ggggagtaat ctgagcttgc aatacacgaa cttcactttg
    40081 tgctaaatgg tattgtttca aagcgttctc ccgtaaagac tggtttagat cttccgccat
    40141 tttattcatg ctagcggtaa gtgtttgtaa ttccagtgtt tccggcaggg ttaaacgaaa
    40201 gccaaggttc cctgaagaaa gttgttctga catctcgatc agctgattga tcggttcttg
    40261 gacctttctc tctaaaaagc gacgattctt tttcgcatag aaaaaaatgg tactaagaac
    40321 tccaagttcc actattgtta atagaatgag cgagcggaca agtgtcgtat tttttttgct
    40381 tgctaagtcg atctccacac gaacaaaatc ttgtaagata tctgacagca gttgagtgac
    40441 agaatctacc tgattgatga tctcttcatt ggtatccata aaatcttttg ccaagatatt
    40501 attgatcagc tcgttttgat aatcttccag tgtatcgatc gtacgtagcg atacatctaa
    40561 cgtactaatt tctttaagtg tatttgtatt atttttgatc tctcgaatat cattcctaag
    40621 ttcttctagg atattttcct cattgaactc atctacggtt acttggccag aaatcaagtc
    40681 ccacatactt tccaaaactt tttgatcaac cttcaaagca attgcatctg ctttttggat
    40741 atttgcgatc gtctgttgat aaatcaaaag ctgttgcgaa tataacagta tgctcagtag
    40801 caaagggata acagcaaata gaagcatggc tttgtttgct tgggcaaaaa tctgttttat
    40861 gcttaaattt tttgtcatga tacttctcca gtcaataatt tctggttggg atgttagcta
    40921 tattctgctg ggaaaagaca gtctcggaaa taaaaatatc tttaggtaat gtttttcctg
    40981 tttgaatatt tccaaaataa cgagtaacgg tattggctac ataccagccg acatcaggtt
    41041 tacactcgac tacacaattg acgattcctg agcgtagctt ctcgatcata tcttcttgtc
    41101 catcaatagt tacaatgatc aaatcttctc caggtttgat tgatgtttct tttatcgcag
    41161 ctaaagcacc gtgagtcatt tcatcactat ggctgtataa tacatcgatt tcggataaat
    41221 catttgtttc taaatatcgt ttcatctggt cttttccttt catccgaata aaatcaccga
    41281 caattcggtg aacaatagtc atcggaggtt tatggtcgat ggttccatct ttttttaggg
    41341 ttggtttacg attgattgat tccaaaaatc cttcggagcg tagcttggtc ggtgtggagt
    41401 tctctgaacc agcaagttct aggattctga tttcctgttt ctttgaattt gtgaagtgat
    41461 tgctgacaaa taaacccgcc cgatttcctt ctgctttgaa actggggcca atgtgggtga
    41521 cgaaaagctc gggatcattc gtttgaatat gtctgtcgac aagtatgaca gggatccctg
    41581 ctcgctttgc ttcttttaat acagagtccc acccggattc ttgcaaagga gtaaaaatga
    41641 tcatatccac tttataggca atgaacgtcc gtatatcttg gatttgccgt tcctgattca
    41701 tgtagccatt tcggtagaga acttggtaat cttctttttc aagcgcagtg ataattgatt
    41761 cagtatgctt tttccgccag ctactctccg ttcctgattg cgaaaaacca acgactagtg
    41821 ggtcaggtgc ttcctttgta ttaggtgtac accccatcat ttggtaagcg attacaacaa
    41881 gggctaaaaa aaataaaaca cgtttcactt taaatcactc catctggatt tgttagtact
    41941 atcttatcag ataaaaggga aaatcaaagt caaaaggaat caatcgaaaa aaatccaaga
    42001 aacttaaaaa aatccaagac aaaaaaagta cacctaaaaa atttaaagta aatcccataa
    42061 aaaaatcaat gttaacgctt tctttattag ctatactcgg tgtatcaatt gaaatggggg
    42121 ataaaaaatg aaaaacaaat ttagaaagat tgttgggact atcgctattt tgaccgcaag
    42181 cattctatta agtgcgtgtg gcaattcagg atctgcagat gatagtacgg ggtatgtagg
    42241 aatcgctatg ccgaccaaat cagcagaaag atggatcgct gatgggaaca acatggtctc
    42301 ggaattagaa aaactgggtt ataaaacaga tcttcaatat ggagaagata aagtagaaaa
    42361 tcaagtagca caaatagaaa atatgattac aaaaggggta gatacacttg tgattgcttc
    42421 tatcgatggt tcggctttaa ctgatgtgtt agctaaagca aaagaagcag atatcaaggt
    42481 gatcgcctat gatcgtttac tgatgaattc agaaaatgtc gattattacg cgacttttga
    42541 taattttgga gtaggtgtat cgcaagcagc ttatattgaa gagcacttag gattgaaaga
    42601 aggaaaagga ccattcacga ttgaattatt tggtggctcg cctgacgaca acaacgcact
    42661 aatcaattac aacggagtga tgtctgtttt acaaccatat atggacaacg gtcagttggt
    42721 cgtgccatct ggacagacga gtttcagtca aatcgctacg cttcgctggg atggttctac
    42781 ggcgcaagca aggatggata atctgttaag cgcaaattat actgaccaaa cattggatgc
    42841 tgttttgtcg ccatatgatc caataagttt aggaatcatt tcgtcattaa aaggcgtggg
    42901 gtatgggagt gaaagtaaac ctttacctgt gattactgga caagatgcga cagttgctgg
    42961 cgttaaatcg atcattgccg gggaacaaac acaaacgatc tttaaagaca cacgtatctt
    43021 agcaaaaaat acgattgaaa tgatcaaagc aatcagtgat ggagaagagg ttccggtcaa
    43081 tgatactgaa acttatgata atggggtgaa aactgtccct acgtatttag caaatacagt
    43141 atctgtcgat aaagataatt atcaagcaga gctgatcgac accgattatt ataaagaatc
    43201 cgatctgaaa aattaagagg aaccaaacaa ggaactaaag agatctaagt cagagagagg
    43261 ataagaatta tggcggattg tattttaaaa atggcagata tcaccaaaaa attttctgga
    43321 atccgagcgt tagattgcgt gaatctgatg attgaacgtg gggaaatcca tgcattgtgc
    43381 ggagaaaacg gagcgggaaa atcaacattg atgaatgtct tgagcggctt gtatccatat
    43441 ggctcctatg acggggaaat cttttatgat ggaaagctgt gtcaatttaa agatttgaaa
    43501 gatagtgaag aaaaaggcat cgtcatcatt catcaagaat tagcactaag tccttatctt
    43561 tcaataaaag agaatatttt tctcggaaat gaacaagcag aaagaggcgt gattgattgg
    43621 gaactgacag aaaagaaaac atatgaactg ctgaataaag tcggtttgtc tatcgacccg
    43681 aatcttctag tatcccagat tggcgtaggg caacagcaac tagttgaaat agctaaagca
    43741 ttatcaaaat ccgtccgtct gttgattttg gatgagccta ccgctgcatt gaatgaagaa
    43801 gaaagcgcga atttgctgag attgatccga gagttgaaag agcaaggtgt aacctccatc
    43861 attatttcac ataagctgaa tgaaatcgtg gatatcgcag atcgaatcac cattttacgg
    43921 gatggacaga cgattgagac actagaaaat gaaatgatca gcgaagagca tattattcgc
    43981 ggaatggtgg gcagagattt agttgatcgt tatcctgaaa gaaaaccgga tattggagaa
    44041 gtttatttta aagtagaaga ctggacggtc tatcaccctc ttgatcacga gcgaatcata
    44101 aacgaccaca tcaacttgca tttgaaaaaa ggagagattg taggaatagc tggactgatg
    44161 ggagcgggca gaactgaatt cgctatgagt ctatttggac attcttatgg aagcaagata
    44221 tccggacgta tattaaagga aggggcagag atatcagtta agaccgttcc ttcagccatt
    44281 gcaaacggac tcgcttatgt ctcggaggac cgaaaatctt taggactgaa tctgctgatg
    44341 gatattcggg aaaacgtgac gctgagcagt ttggataaaa taagtcaaaa aggagtatta
    44401 gataaagaaa aagaagtaac tgaggcagaa aatttccgga aaaagatgcg tataaaaaca
    44461 aactccatcc atcaaattgt cagtagtctt agtggtggga atcaacaaaa agtcgtttta
    44521 tccaagtggc tgatgacaca acccgatatt ctttttttgg atgagccaac ccgtgggata
    44581 gatgttgggg caaaatatga gatctacacg attatcgaag aaatggcagc aaatggcaaa
    44641 gctgtctgtc ttatctcttc tgaacttcct gaaatattag ggatgtgtga tcgaatctat
    44701 acgatgaacg aaggacgtat tacaggagaa gtctcgcgag aagatgcaga tcaggaagtc
    44761 ttgatgaaat taatgacgaa agaagaggtg ggttaagttg gaacaggcaa aaaatcttac
    44821 ggataaaaaa gagaaaaaac taaatttgaa aagtagagca gctgatcttt ttggtcgcta
    44881 cagcatggtg atcattttag cgggactact tattgcgttt caattgatga cggatggtat
    44941 tttctggcgt ccattgaata taactaacct tgttctgcaa aatagccata tattagtact
    45001 agctgcaggg atgttattag ttgtgctctt aggtcatgtg gatttgtcgg tagggtcagt
    45061 gatggcgttt gttggtgcaa ttgcgggcat gatgatggtc aatcgccaaa tgaacccgtg
    45121 gatgacagtt atcgcatgtc ttgcagtagg cgggctgatc ggcgcatggc aaggtttttg
    45181 ggtagcttat gcagggatac cggcgtttat cgtgacttta gcaggattgc tgatgtttcg
    45241 tggactgaca caagttgttc taggaggcca atctctagca ccttttccag ctgttttcca
    45301 aaaaatgtct acgggttatt taccagactt aagcgaagga agcagccttc acttcttgac
    45361 attgatttta ggaatgatca tcacgatcgt gttagttgtt ggtcaatggc gaacaagaaa
    45421 tcgtcggaaa aatcatttat ttgaagtgga atctccaaca gctttcttgg taaaggcggt
    45481 atttacagca gtcgttgtac taggaataac ttatatcttt gcctcttatc aagggtatcc
    45541 gattattttg atcattcttg gtttgatcgt tgcagcatat gggtttttga caaataaaac
    45601 agtagcaggt cgacagattt atgcgacggg cggaaatcga aaagcggctg aactatcagg
    45661 gatcaaaaca aagcgaatca cgttctgggt attcgtcaac atgggagtca tggcagcttt
    45721 agctggatta gttttagctg ctcgattgaa tgcggcaaca cctcaagcag gtacatcgat
    45781 ggaactggat gcaatggcgg cagtatattt tggtggtgct tcgacttccg gcggcattgg
    45841 aacaatcatg ggtgcgattg tcggtggctt ggtcatgggt gtattgaaca atggcatgtc
    45901 gattttaggc gtcggggtag actggcagca ggcaatcaaa ggattgatct tgcttttagc
    45961 cgttgtgcta gacttgtata ataagaaaaa acgaacaacg taggagaacg ccggttattc
    46021 agaaaaaaga ctgtgacaag acatttgtca cagtcttttt ttcgctaaaa gcgaacattc
    46081 attgtttcgt ttgtatagac taaaaataat atatgttttt ttaccattcg tataaattct
    46141 ctttttgctc ttgatttttt tgcttaattg agttaaatta catagggcgc taaaaaaagc
    46201 cttgattaaa ttaataatgt tcgtgttttg ctggatgtga acatcaggag gataatgtaa
    46261 tgaaagtatt tgattacgaa gatattcaat taattcctaa taaatgtatc gtaaatagcc
    46321 gttctgaatg tgatacaacg gtcacattag gtaaacatac attcaaaatg ccagtagtgc
    46381 ctgccaacat gcagacgatt attgatgaaa caatcgcaga attcttagcg gaaaatggtt
    46441 atttctatat catgcatcgg tttgatgaag cagctcgaat tccgtttatc aaaaaaatga
    46501 aaaagcgtgg attgattacc tcgatcagtg ttggcgtcaa gaaagaggaa tattccttta
    46561 tagagaagtt ggcagaagaa tcgctaaatc ctgattatat cactatcgac atcgcgcatg
    46621 gacatgctaa ctcagttatt gatatgattc agcatattaa aaaatatttg cctgaaactt
    46681 ttgtgattgc cggtaatgtt ggtacaccgg aagccgtccg tgaattggaa aatgcgggcg
    46741 cagatgcaac aaaagtcggg attggtccag gaaaagtatg tattacaaaa atcaagacag
    46801 gctttgggac tggaggctgg caactggcag ctcttagatg gtgtgcgaaa gcagctcgca
    46861 agccgatcat cgctgacggt gggatcagaa cacatggcga tattgcaaaa tctgtccgtt
    46921 ttggtgcgac aatggtcatg attggttcat tgtttgccgg tcacgaggaa tctcctggcg
    46981 aaacaaaagt cgaaaatgga atcgtgtata aagaatactt tggttctgct tcagaattcc
    47041 aaaaaggcga aaaacgaaat gttgaaggaa agaaaatctg gatccaacac aaaggatctt
    47101 tgaaagatac actagtggaa atgcaacaag accttcaatc atctatttct tatgctggag
    47161 gaagagatct ggaagccatt cgaaaagttg actatgtcat cgtgaaaaat tcgattttta
    47221 atggagacac aatctaaaaa ataaataaaa tattaggatg ttgtgaaaaa gttgtcctgc
    47281 attaagtaat aagaacagcc aaacaaaaat agttctttat atgttttgtt tggctggaat
    47341 tattatcgca gatacaagct tttgaacatc attattcaga ataagggact gtgataagat
    47401 ttttgtcaca gtcccttatg ttttgcaaaa aaagtttttc ttttttctcg taaattcggt
    47461 aaaatcaaaa gaaaaaatag acaatagaaa agagaagctt atgtgggaaa aagtagagaa
    47521 aaaacaagga ccgatttatc gtcaaattat ggaacagatt atgagagaaa tcgaaaacgg
    47581 aaggatcaat cctggaagtc aacttgaatc agaacgaaaa ctagggcaac tttttggtgt
    47641 gaatcgttcc accgttgtcc atgcattgga agagcttagg gagcttgggg tactaacgag
    47701 caaacgtggc agcggatggt ttgttaatca gactgaatgg gggaaattcg ctgttccaag
    47761 aatcgattgg cggcaaatga tctctcctcg ttatgagcag acggactggt atgagcaaaa
    47821 aataagagaa gcaaagcaga tccaaaaaac atcgtttctt gatttatacg ctagcgagat
    47881 gccagatgag cttttgccga attttgagtt tccttcttat tctcttgaag aaatcttagc
    47941 ggaagaaaaa gaaatggatc ttttaggcta tactccgtta cgtaacaaaa tcaaacggta
    48001 tttggaaagt aaatttgaat tggcattttc ccccaaccag cttcttgtga ctggtggcgg
    48061 tcagcaagca atctttttga ttttacaaac gattctttca gctggagagg ggatagctgt
    48121 agagtcacct tctttttttt accgattacc tcttttcaaa gcttcaggaa cgcgtttatt
    48181 tgggataccg atggatgaag aagggatcga cttagaaaaa ctgaaagaat cgatccataa
    48241 aaataaattg aaagcagtgc ttatcaaccc gaattttcaa aaccctacag gaaaagtgat
    48301 gagtcaaaaa cgacgagaaa agctagtaga attgtgtcga cagtatcggc ttccaattat
    48361 tgaagacgat gtatttacgg atctttcatt tctaaaccaa gaagaagtcc ttcctatacg
    48421 aacgattgat ccggataatg tgttatacgt cggttcgtta tctagggttt taggaaaaac
    48481 aacgaaaatc ggttgggtga taggacctga gacttttatc tcgcaactag ctcaagcgca
    48541 agaaatgatg gagttttcga tgaatatcct tacacaaatc acagtggcta atgtatttaa
    48601 tgaagcaatt gatttgaaaa tgcaagatgt aagaaaaaag ttgaaagaaa aaagccgact
    48661 gataagcgct tggggagatt cacaatcgtt tttcaagctt cattcaattt taggtggtta
    48721 ctatgcctgg attacttggg atgggaaaaa actagacccc gaactagcag aaaaagtagt
    48781 agatatgggt cttggaattg caccaagtct actttttggg caagatataa atggaatcag
    48841 aatcaattac agtaggctgg atgaaaacca aataccgttg ttttattcaa agatgaaaat
    48901 tctagaaaag tggttaacag aataatttca caaagtaaat agattaaaga atataacagc
    48961 ttggatttaa atttcaagct gtttcttttt tttcggaaaa agaatacgat ataaagaaac
    49021 taagaaaaaa ccattatttg tacgtccgtt cacgatgtgt aaataaaata aatgtttgca
    49081 acaaaactgt ataacaccaa cgtttttaaa tagaaacaga tggttgtaag tttgattaga
    49141 aaatagaaaa aatgcagatg aaatataaaa cgctttcctt attgtgattt tattcactaa
    49201 tgctgttaat atgcggattg gcataatttc ctttcatcgt gaaaatttgt gcttttagct
    49261 tgtatttctc ataaatccat gataatttat taatgaagac ggttaaatag tgatacagtt
    49321 ttattcactg tttcaatcgc agaatgaaga gattttctta tagatgagag aggaatgtgt
    49381 gacaaatggc aaacaaaaaa gcaccgatcg acttccaagc actgctagat gaagtcaatg
    49441 cagatttccc agtatatcaa gcacttgatc aagatggaaa cgtagttaac aaagatttag
    49501 tacctgattt atccgatgat gaactcgttg aattaatgac tcatatggta tggtctcgtg
    49561 tattagacca acgttcaaca gcgctgaacc gccaaggacg cctaggcttt tttgcaccaa
    49621 ctgctggaca agaggcaagt cagctggcta gtgcttacgc atttgataaa gaagatgttc
    49681 ttcttccagg ttatcgggat gtacctcaac tagtaaaaca tggtttacct ttatctcaag
    49741 cttttttatg gtctcgagga catgctgcag gtaattctta tccggaagaa ttgaaagctc
    49801 taccaccaca aattatcatc ggtgcacaat atgtacaagc agccggtgtt gcattaggtt
    49861 tgaagaaacg aaacaagaaa aatgtcgtct tcacttatac tggtgatggc ggttcatcac
    49921 aaggtgattt ttacgaagca atcaatttcg ctggcgctta ccatgcaaat gccgtatttt
    49981 atatccaaaa caacgggtat gcgatctcta cacctcgtga aaaacaaact gcagcaaaaa
    50041 cacttgcaca aaaagctgtc gcagctggga ttcctggtat tcaagtcgat ggaatggatc
    50101 cgcttgcagt atatactgta tctaaaatgg cacgggaatg ggcgatcagt ggaaatggac
    50161 cagtcctaat cgaaacactg acttatcgtt atggaccaca tacactatct ggtgacgatc
    50221 caacccgcta ccgtacaaaa gacacagatg acgattggca gaaaaaagat ccattgatcc
    50281 gcttccgtaa atatttgacg gaaaaaggac tttggtctga agaaaaagaa gaacaagtca
    50341 tcgaagcaac taaagaagaa atcaaagcag ctattgctga agccgacaaa gtaccaaaac
    50401 aaaaggtttc agatttcttg aaaaacatgt tcgaagtatc tccacaatca atcaaagaac
    50461 aaattgcaat ttatgaagcg aaggagtcga aataatcatg gcacaaaaaa caatgatcca
    50521 agcaatcaca gatgccttag cacttgaact agaaaatgac gagaatgtcg ttgtttttgg
    50581 tgaagatgtt gggaaaaacg gaggagtttt ccgggcaact gaaggattgc aggaaaagtt
    50641 cggagaagac cgagtattcg atactccttt agctgaatct ggaatcgcag gattgagttt
    50701 cggtcttgcg ttagaaggat ttcgtccagt tcctgaaatc caattctttg gttttatttt
    50761 cgaagcaatg gacgaagtag tagctcaaat ggctcgtaca agatatcgaa tgagcggcac
    50821 tagaaatcta cccatcacaa ttcgttcgcc atttggtggc ggtgttcata caccagaatt
    50881 gcattcggat aatttagaag gtttgatcgc tcagtctcct ggtattcgag tagtgattcc
    50941 ttccaaccct tatgatgcaa aaggactatt gatttcttct attagaagta acgatccggt
    51001 tgttttccta gaacacatga aactatatcg ctcattccga gaagaagtgc cggatgaagc
    51061 ttacgaagtt cctttggata aagcagcagt tactcgtgag ggaacagatg tatctattat
    51121 cacatacgga gcaatggtgc gtgaagcaat caaagcagca gacaatcttg caaaagaaaa
    51181 tatatctgtt gaaatcattg atcttcgtac agttgcgcca ttagatgtag aaacgatcat
    51241 tcaatccgtg gaaaaaactg gtcgcgtagt tgttgtccaa gaagcacaac gacaagcggg
    51301 cgttgccgcg caagtagttt ctgagatctc agaacgcgct atcctttcat tagaagcccc
    51361 aatcggacga gtttctgcac ctgatacagt cttcccattt ggacaagcag aaaatgtctg
    51421 gttgccaaat gcaaaagata tcgaagacaa agtaaaagaa atcgcggaat tttaagaaaa
    51481 gaagggacga aacaaagtca tggcttatca atttaaatt
//
LOCUS       DAZKKZ010000015        50859 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.015, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000015 DAZKKZ010000000
VERSION     DAZKKZ010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 50859)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 50859)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..50859
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.015"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            123..494
                     /locus_tag="ACG8LA_000912"
     CDS             123..494
                     /locus_tag="ACG8LA_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cro/Cl family transcriptional regulator"
                     /protein_id="HFQ0203228.1"
                     /translation="MRDYVTDKTQEVINQSQSLNELSDKAKEEAVAIISSGISDYIDM
                     SGEINYGDKDKIVRMIKAFIKTFDVKADLKFNDTYLVGKLINILGTEKDTETFISSLS
                     MLFTDKHFSTQLGGEELVEIF"
     gene            complement(768..1460)
                     /locus_tag="ACG8LA_000913"
     CDS             complement(768..1460)
                     /locus_tag="ACG8LA_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFQ0203229.1"
                     /translation="MKGIIFDFNGTMFLDSHLHEAAWLHMIHDHTKDGLSDEDILKNI
                     HGRTNTEILKHFISEHLTASEIAVLSEEKESYYRMLCLQNENELQLTKGLEATLDQLT
                     DQQIPLTIATATVKENVAFYFDIFDLARWFDWDKIVYDDGSFPGKPQPDIFLKAADKL
                     SLAPADCLVIEDAYSGLLAAKRAGIGTIIAIDPFGKNKTVFEQAQLNKDGTIKDFTGF
                     WTEHLSATSVNS"
     gene            complement(1463..2248)
                     /locus_tag="ACG8LA_000914"
     CDS             complement(1463..2248)
                     /locus_tag="ACG8LA_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HFQ0203230.1"
                     /translation="MLKKERLLTIVEMVNKKGILTVNEIINQLDVSDMTVRRDLDELE
                     KSGKLLRVHGGAQSLSYTLDQELSHTEKATLQIQEKKEIAATAASLIHEGETIFLGPG
                     TTIELLATHLLNKKIRIITNNYPVFDILAQADGPEILLIGGDFRKNTGAFVGPITNDN
                     LRRLKFTKAFISSNGVHNEAISTYSTEEGEAQQIALNNSRKKYLLVDNKKFNRDDFYV
                     FYNLHDFDLLITDRQISREVQEHYAQYVDLQIADSTENTTIGA"
     gene            2485..3885
                     /gene="lacG"
                     /locus_tag="ACG8LA_000915"
     CDS             2485..3885
                     /gene="lacG"
                     /locus_tag="ACG8LA_000915"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033920 - 6-phospho-beta-galactosidase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HFQ0203231.1"
                     /translation="MLKLPEDFIFGGATAAYQVEGATKEGGKGAVAWDDFLEEQGRFS
                     PDPASDFYHQYAKDIELCERFGVNGLRLSIAWSRIFPDGAGKPNPEGIAFYHRVFEEC
                     KKRNVTPFVTLHHFDTPKRLFDHGDFLNRETIEAFVSYAIFCFHEFKEVKVWSTFNEI
                     YPVATNQYLLGVFPPGIKYDFTKIVACLHNMMVAHARVVNYFKENELPGEIGVVHSLE
                     TKYAATDAPEDKHAAFLDDALSIRFLLDATYLGYYSTETLTALDEICEANQASYHFPE
                     EDFVELKKASTRNDYLGINHYQCHFVKAYDGENAIHHNGTGEKGTSVYKVKGIGERIY
                     KEGIPRTDWDWLIYPEGLYDLLLRIKSDYPHYNKIYITENGMGYKDQFEDGIIMDQPR
                     IDYLRVYLESLSKAITAGVNVKGYFLWSLMDLFSWTNGYNKRYGLFYVDFETQKRYPK
                     ESAYWYKLVSETKTII"
     gene            3910..4227
                     /locus_tag="ACG8LA_000916"
     CDS             3910..4227
                     /locus_tag="ACG8LA_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010749967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HFQ0203232.1"
                     /translation="MNKEELQMLGFEIVAYSGDARSTLLKLLKEVRQGNFEHVDSALK
                     EADENLTLAHNSQTKILAEEASGKEMEMGFIFIHGQDHLMTTLLLRDLIQDFIVLYRQ
                     NQG"
     gene            4240..5913
                     /locus_tag="ACG8LA_000917"
     CDS             4240..5913
                     /locus_tag="ACG8LA_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose transporter subunit IIBC"
                     /protein_id="HFQ0203233.1"
                     /translation="MDGIIKQIEKGKPFFEKISRNSYLGAVRDGFLTAMPAILFSSIF
                     ILIAAVPEIFGYQWPESVSTWLWKVYNYSMGVVGLLVSATTARCLADSMNRRLPKNKV
                     INTTSVMLASVVSFLLLSVSPIEGGFSTEYMGTKGLLASFVAAFLTVNLYKFCVLKDI
                     TIKMPKEVPGTISQTFRDIFPFSFSVFAAVLIDLGIRQIFQISFAEAIITVLQPLFTA
                     ADGYLGIAIIWGAMALFWFVGVHGPSIVEPAIAAIIYANVETNLQLFNSGEQASKVLT
                     VGLGNFVGTMGGTGATLVVPFIFLLFAKSKQLKAVGKASFIPVSFAVNEPLLFAAPMI
                     LNPYFFIPFLLTPVVNVCLFKFFVDVLGMNSFMYVLPWATPAPIGLVLGTGMGILAFV
                     LAAVLIVVDFLIYLPFCKAYDAVLVEKEAQKAEVIATEEGASADVREEVPVAASQVIS
                     DANKEINVLVLCAGAGTSAMLANALKKGASESKAPISAMAGAYGSHYEMLQDFDMVVL
                     APQVNSYYDDIKEDTDRLGIKLVATKGAEYIGLTRDPEKAVQFILNQFQ"
     gene            5927..7558
                     /locus_tag="ACG8LA_000918"
     CDS             5927..7558
                     /locus_tag="ACG8LA_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arabinogalactan endo-beta-1,4-galactanase"
                     /protein_id="HFQ0203234.1"
                     /translation="MKMGIWLRKAVLFAAVLGALGAVSKTVEASASEFIRGADISILS
                     DMEKSGAKYYEDDISKDALEILKNNGVNYVRLRLWQDPYNSNGESYGAGTNDLETTID
                     LAKRAKNLGLKVLLDFHYSDFWVDPGKQNLPKAWQGLTFEEMNTALYDYTKNVLSEMK
                     QLDVYPDMVQIGNELNSGMLWPYGKSWGEGGGEFDRLAAFLKSGIQAVRDTQPKTTPV
                     MLHLADGGDTGAFTWWFDEITSRGVSFDLIGVSYYPYWHGSMNELQTNMNAISQRYGK
                     EVIVVETAYGHTTANADTMPNAFGEAEAAAGGYEPTPTGQAEYLLDLADRIQAVPNNR
                     GAGFFYWEPLWYNGNVSWATQAGMNYLSVQSTMGNEWDNQAMFDFAGNALPSLRAFKQ
                     AGAQINLVKNASFESDGPTTSPSNWQTWFQQGTAKGTIKTEAGTFFGDYKLTFWQDQA
                     YEASAYQNVSGISKGTYTLSAYVMSGGEFDTNQLYIKNYGGAELNTAVVKTSEWTKIT
                     IKDIPITTGVCEIGVYSKASGNAWTNVDFVSLVKQ"
     gene            complement(8049..9614)
                     /gene="guaA"
                     /locus_tag="ACG8LA_000919"
     CDS             complement(8049..9614)
                     /gene="guaA"
                     /locus_tag="ACG8LA_000919"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003922 - GMP synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016462 - pyrophosphatase activity
                     [Evidence IEA];
                     GO_process: GO:0006177 - GMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HFQ0203235.1"
                     /translation="MTNVADMTNVEKIIVLDYGSQYNQLITRRIRDLGVFSELLSHRI
                     TAEEVKAMNPKGIILSGGPNSVYDENAFGIDPEIFNLGIPVLGICYGMQLITYKLGGS
                     VEPAKNREYGKALLEVTSDQAVLFKETPKQQTVWMSHGDLVTKVPEGFETVGTSKDCP
                     IASIQDTTRNFYGIQFHAEVRHSEYGIELLRHFAFDVCHCEGNWTMDNFIDMQVEKIR
                     EQVGDKKVLLGLSGGVDSSVVGVLLQKAIGDQLTSIFVDHGLLRKGEAEQVMESLGGK
                     FGLNIIKVNARDRFLDKLKGVSDPEQKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQG
                     TLYTDVIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRELGTQLGMPDS
                     IVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILREEIAAAGLDRDIWQYFTVLPGI
                     RSVGVMGDGRTYDYTVGIRAVTSIDGMTADFARIPWEVLQKISVRIVNEVAHVNRIVY
                     DITSKPPATVEWE"
     gene            complement(9673..10596)
                     /gene="coaA"
                     /locus_tag="ACG8LA_000920"
     CDS             complement(9673..10596)
                     /gene="coaA"
                     /locus_tag="ACG8LA_000920"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004594 - pantothenate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HFQ0203236.1"
                     /translation="MNDPMNYYRVAREEWREFYRNGQAPLTQDELDNIKSLNDRISMQ
                     DVRDIYVPLAHLIYLYMKEFESLFLSKGLFLHKYVEVPPFIIGIAGSVAVGKSTTARL
                     LQTILSRTFKRRNVQLITTDGFLYPNRILKERGIMDRKGFPESYDMEMLIDFLNRVKS
                     GQEEIKVPVYSHDVYDIIPDKYELIQQPDILIVEGINTLQLPANQQIYVSDFFDFSVY
                     VDADPVLIEKWYLDRFGALLDTAFQNPENYYYRFAIGDREEAFKMAKDVWKNVNLKNL
                     QEYILPTRGRADIILHKTENHIIDSIFMRKY"
     gene            10792..11397
                     /locus_tag="ACG8LA_000921"
     CDS             10792..11397
                     /locus_tag="ACG8LA_000921"
                     /EC_number="2.1.1.172"
                     /EC_number="2.1.1.174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0052916 - 23S rRNA
                     (guanine(1835)-N(2))-methyltransferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFQ0203237.1"
                     /translation="MTNHYYSERPDTAHDFEQWAFELKGRTFQFVTDSGVFSRETVDY
                     GSRVLIDAFDWEELPDEGKILDVGCGYGPIGLALAFATQRFVEMVDINERAVSLAQGN
                     AKRNQIEHVDIHQSNIYEAVHEETYAAIVSNPPIRAGKKVVHEILTGAYPRLKKGGTL
                     TIVIQKKQGAPSAQKKMEETFGNAEIVTKDKGYYIIKSVKE"
     gene            11705..12721
                     /locus_tag="ACG8LA_000922"
     CDS             11705..12721
                     /locus_tag="ACG8LA_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFQ0203238.1"
                     /translation="MKLTIRDIAEMAGVSVTTVSQILNNKGSRFSDKTRKKVLSIVNE
                     HHYKPDYFASNVINRHSKTIGMIVPDVTDFFFSKLIEGVESYLNPLGYVIMLCNSRHS
                     QENEIKYLQELSHRSVDGILLATPNILPEKYALDSGFYQKMPIILIDRGLNRRDNGRL
                     IVKEYEGAYQAVSLFIENGHTKIGMLKETTGYYQLEERFNGYRHALKDHGLPFNGKFV
                     EHGELTVQGGYTASKKLLKHKDITAIFCGNDAMAIGCYQAIDELGKKIPEDISVIGFD
                     GLKLSEYMIPQLTTVQQPSFDIGFYAARFLIDTIEFPQRKVPNKVFETKLIIRESVKV
                     LTKG"
     gene            12862..14163
                     /locus_tag="ACG8LA_000923"
     CDS             12862..14163
                     /locus_tag="ACG8LA_000923"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016154 - pyrimidine-nucleoside
                     phosphorylase activity [Evidence IEA];
                     GO_process: GO:0006213 - pyrimidine nucleoside metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HFQ0203239.1"
                     /translation="MRMVDLIEKKRDGNELSKEEIEYIVTNYTNGKIPDYQVSALLMA
                     IFYQDMTNEEITNLTLAIANSGDVIDLSSLEGIKVDKHSTGGVGDTTTLILAPLVASV
                     GVTVAKMSGRGLGYTGGTLDKLEAIPGFQIELSDEEFVRIVNESKVAVIGQSGNLAPA
                     DKKLYALRDVTATVDSLPLIASSIMSKKIAAGADAIVLDVTTGDGAFMKNIEDARRLA
                     KTMTSIGKLANRETVAVISDMSEPLGEAIGNSLEVVEAIETLQGNGPEDLVEMCYALG
                     SQMVVLAGKAKTTDEARTLLQEALESGKALAKFKEMIQNQGGDPAIVEHPERILTARY
                     TMELPAKQSGVVSKIVANELGIAAMMLGAGRKTKEEDIDHAVGLKLHKKIGDTVTKGE
                     SLLTIYSNDEEITSVIELLYKNIEIGESAMKPTLIHDIITE"
     gene            14209..14871
                     /gene="deoC"
                     /locus_tag="ACG8LA_000924"
     CDS             14209..14871
                     /gene="deoC"
                     /locus_tag="ACG8LA_000924"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004139 - deoxyribose-phosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0009264 - deoxyribonucleotide catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HFQ0203240.1"
                     /translation="MELNRMIDHTILKADASKEAVMQIIEEAKKYHFYSVCINPAWVA
                     LAKEQLQGEPVAVCTVIGFPLGANTPETKAFETTDAINNGADEVDMVINIGALKSKDD
                     QQVQKDIEAVVEAAKDRALVKVIIETSLLDREEIIRACEIAKAAGADFVKTSTGFSTG
                     GAKVEDVRLMRETVGPEMGVKASGGIHNEEEAMAMIEAGATRIGTSAGVAIVSGSTGE
                     GY"
     gene            14892..15290
                     /locus_tag="ACG8LA_000925"
     CDS             14892..15290
                     /locus_tag="ACG8LA_000925"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004126 - cytidine deaminase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0009972 - cytidine deamination [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HFQ0203241.1"
                     /translation="MAELKQEWINTAIEALDKAYVPYSHFPVGACLVTESGKIYQGIN
                     IENASFGLTNCAERTAFFKAVSEGEKTFTHLVVAGHTPDPISPCGACRQVMAEFCSPD
                     MPVTLVGDNGVTKATTVRALLPYAFTEKDL"
     gene            15356..16438
                     /locus_tag="ACG8LA_000926"
     CDS             15356..16438
                     /locus_tag="ACG8LA_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HFQ0203242.1"
                     /translation="MKKAKLFGLGAVALAAGLFLGACGNNGSTDSSGGKSSSDTTTAA
                     LITDTGGVDDRSFNQSAWEGLEKWGKDQGLSRGNDGFQYFQSSNESDYIPNIDQALNA
                     GFKTIFGIGYKLKPAIQEQATNNTGTNFVIIDDVIDGLDNVVSATFKDNEASYLAGVA
                     AAYTTETNVVGFIGGVKGEVIDRFDAGFKAGVDAGAKELGKEIKVLNQYAGDFSAPDK
                     GRSIAQGMYAQNADIIFHASGGTGNGVFQEAKSLNESGDKKVWVIGVDRDQSDEGEYT
                     LNGEKKNFTLTSTLKAVGTVVEDLAQKSADGKFPGGEHTVYGLKEDGVGLTEGQLSDE
                     AKKAVDEAKEKIISGDVKVPETPEEN"
     gene            16650..18212
                     /locus_tag="ACG8LA_000927"
     CDS             16650..18212
                     /locus_tag="ACG8LA_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0203243.1"
                     /translation="MVQENIVIEMQNITKEFGTFKANDNINLQVKAGEIHALLGENGA
                     GKSTLMNVLSGLLEPTSGKILMRGKEVKITSPTKANQLGIGMVHQHFMLVDAFTVTEN
                     IVLGSEPSRAGMLDHKKARKEIQKVSEQYGLSVNPDAYVRDISVGMEQRVEILKTLYR
                     GADVLIFDEPTAVLTPQEIDELIVIMKELVKEGKSIILITHKLDEIKAVADRCTVIRR
                     GKGIGTVNVKDVTSQQLADMMVGRTVSFKTMKKEAKPQEVVLSIENLVVKENRGLEAV
                     KNLNLEVRAGEVLGIAGIDGNGQSELIQALTGLRKAESGHIKLKGEDITNKKPRKITE
                     HGVGHVPEDRHKYGLVLDMTLSENIALQTYHQKPYSKNGMLNYSVMNEHARELIEEYD
                     VRTTNELVPAKALSGGNQQKAIIAREVDRDPDLLIVANPTRGLDVGAIEFIHKRLIEQ
                     RDKYKAVLLISFELEEILNVSDRIAVIHEGEIVGIVDPKETSENELGLLMAGYTLEEA
                     RKELEKGAGAHE"
     gene            18205..19338
                     /locus_tag="ACG8LA_000928"
     CDS             18205..19338
                     /locus_tag="ACG8LA_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFQ0203244.1"
                     /translation="MNDRSEKFRNLLVPVLSVVLGLILGAILMAAFGFQPIQGYSSML
                     DAALGSQRGIGETLRQATPLIFTALGFSVANSAGFFNIGLSGQALCGWIVSVWVALAF
                     PDLPKVVLLPLCVILGALAGAMAAAVPGLLRAFFGTSEVIVTIMMNYILLYVSTFALH
                     EVMPESYRSSLDSSNMISQNASLRLPWLTQAFGGSRVNSGLFLAIIALIFVWLLMKKT
                     TLGFEIRSVGLNPFASEYAGMSSKRTIVLSMVISGALAGLGGVVEGLGTYQNFFVQTT
                     SLSIGFDGMAVSLLGSGSAIGILLSAILFSILKIGGLGMQTGAGVPFEIVNVSIALII
                     FFVGINFLIRFVMAKVFQGKKQEEIVATIESKPTNQNHEGGEL"
     gene            19338..20294
                     /locus_tag="ACG8LA_000929"
     CDS             19338..20294
                     /locus_tag="ACG8LA_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFQ0203245.1"
                     /translation="MSTIELIALILTSTLVYSTPLILTSLGGTFSERSGIVNVGLEGI
                     MVMGAFSSIVFNLTMSPSLGSMTPWIAILVGGVVGILFSLIHAVATVSLRADHIISGT
                     VINLMAPALGVFLIKAWYGKGQTDNITQNLGYFSFPGLADIPVIGPIFFKNTFLPAYC
                     AILIAVLAWVIIFKTKFGLRLRSVGENPQAADTLGINVYAMRYSGVLISGLLGGMGGA
                     VFAQSISGNFSAGTIVGQGFISMAAMIFGKWNPLGAMGASLFFGFAQSLSIIGAQLPV
                     ISSIPPVLLQIAPYLLTIIVLVVFLGKASGPKANGKNYIKSK"
     gene            20393..21559
                     /gene="deoB"
                     /locus_tag="ACG8LA_000930"
     CDS             20393..21559
                     /gene="deoB"
                     /locus_tag="ACG8LA_000930"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008973 - phosphopentomutase activity
                     [Evidence IEA];
                     GO_process: GO:0009117 - nucleotide metabolic process
                     [Evidence IEA];
                     GO_process: GO:0043094 - cellular metabolic compound
                     salvage [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HFQ0203246.1"
                     /translation="MFKRVHLIVMDSVGIGEAPDADKFGDVGSDTLGHIAKEAGLNVP
                     HLEQLGLGTIRPLEGVESVKDHQGYATKLEEVSVGKDTMTGHWEIMGLNIKTPFRVFP
                     NGFPDDLIKQIEEFSGRKVVCNKPYSGTAVIDDYGEHQMKTGDLIVYTSADPVLQIAA
                     HEEIIPLEELYRICQFVRDITKDDPYMIGRIIARPYVGEPGDFTRTSNRHDYALNPFG
                     HTVLDSLKEAGKDVIAVGKINDIFNGQGITESVRTKSNMDGVDQLLKVMKNDFSGISF
                     TNLVDFDALYGHRRDVVGYAHAIEEFDLRIPELLEAMEEDDLLMITADHGNDPTFTGT
                     DHTREYVPLLVYSKKMKEQGALPQGYYSDISATIAENFSVSSTENGESFLKLLK"
     gene            21583..22401
                     /locus_tag="ACG8LA_000931"
     CDS             21583..22401
                     /locus_tag="ACG8LA_000931"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HFQ0203247.1"
                     /translation="MTKLSEMLQETTQFILDKGVKEIDFGLILGSGLGELADEIEDAV
                     MISYDEIPFFPVSTVVGHAGKLVYGSLAGKKVLAMQGRFHYYEGHSMQTVTYPVRVMA
                     GLGAHSVIVTNACGGVNESFVPGDLMLITDHINFTGENPLIGPNEDAMGPRFPDMSQA
                     YTPDYQATAKAAAEKLGLDLKEGVYMGYSGPTYETPAEIRMSRTIGADAVGMSTVPEV
                     IVAAHSGLKVLGISCITNLAAGMQANLSHEEVVETTQRVKQSFKALVKETLTLL"
     gene            22418..23125
                     /gene="deoD"
                     /locus_tag="ACG8LA_000932"
     CDS             22418..23125
                     /gene="deoD"
                     /locus_tag="ACG8LA_000932"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HFQ0203248.1"
                     /translation="MSVHIEAKEGEIADKILLPGDPLRAKYIAETFLEDPVCYNQVRG
                     MLGFTGKYKGERISVQGTGMGMPSATIYAHELIQSYGVKKLIRVGTCGALSKDVHVRD
                     LVLAQGAATSSSMIEKNFQAFHFPPISDFNLLLKAYEIAKEKGYTVHVGNVLSEDSFY
                     KDDLTETFQLAELGVLGVEMEAAALYYLGAKYHVQTLSLMTVSDHLITGEETTAAERQ
                     STFNEMIEVGLETAIAE"
     gene            complement(23423..24109)
                     /gene="gpmA"
                     /locus_tag="ACG8LA_000933"
     CDS             complement(23423..24109)
                     /gene="gpmA"
                     /locus_tag="ACG8LA_000933"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004619 - phosphoglycerate mutase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HFQ0203249.1"
                     /translation="MPKLVFSRHGLSEWNALNQFTGWADVNLAPEGIEEAKEGGRKIK
                     EAGIEFDVAYTSVLTRAIKTCNLILEYSDQLWVPQIKSWRLNERHYGKLQGLNKKETA
                     EKYGDEQVHIWRRSYDTLPPLMEETDEGSAANDRRYAMLDKRDIPGGENLKVTLERAL
                     PFWQDEIAPALLDNKTVLVAAHGNSLRALAKHIEGISDEDIMDLEIPTGQPLVYELND
                     DLTVAKKYYL"
     gene            complement(24281..24862)
                     /locus_tag="ACG8LA_000934"
     CDS             complement(24281..24862)
                     /locus_tag="ACG8LA_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFQ0203250.1"
                     /translation="MKIIGYARTTINDVDLTTQVDQLSDFGCQEIFHETYEVEQNDST
                     AVHLESVIADMQQGDALVICQLHRLGKSTRQLTELTQLFKDRGLHLISLDEGIDTREM
                     GKIYFQLMENLANMECALIKERTLVGLDEARKKGKIGGRPKIDAKTIKKIRRLYYEKK
                     ETIQFISSKCGVSVGTCYKYINLPEKEIEQLCI"
     gene            complement(24995..25678)
                     /gene="rpiA"
                     /locus_tag="ACG8LA_000935"
     CDS             complement(24995..25678)
                     /gene="rpiA"
                     /locus_tag="ACG8LA_000935"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004751 - ribose-5-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0009052 - pentose-phosphate shunt,
                     non-oxidative branch [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HFQ0203251.1"
                     /translation="MNLKQLAGIEAAKFVKDGMIVGLGTGSTAYYMVEEIGRRMREEG
                     LRITGVTTSNATKEQAEKLGIPLKSIDEVPVVDLTIDGADEISADFQGIKGGGAALLF
                     EKIVATYSKETIWIVDSSKLVDKLGKFPLPVEVIPYGSQQLLHIFEEKRFQPVLRTDE
                     NGEVLTTDGGHYIIDLHLEVIEQPESLATYLDELVGVVEHGLFLNMVSKVVVGSEKGV
                     EILDAIRRK"
     gene            25997..26410
                     /gene="rpsL"
                     /locus_tag="ACG8LA_000936"
     CDS             25997..26410
                     /gene="rpsL"
                     /locus_tag="ACG8LA_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HFQ0203252.1"
                     /translation="MPTINQLVRKPRKSKVEKSNSPALNKGYNSFKKTQTNVNSPQKR
                     GVATRVGTMTPKKPNSALRKYARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQSRSKYGTKKPKA"
     gene            26494..26964
                     /gene="rpsG"
                     /locus_tag="ACG8LA_000937"
     CDS             26494..26964
                     /gene="rpsG"
                     /locus_tag="ACG8LA_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HFQ0203253.1"
                     /translation="MPRKGPVAKRDVLPDPIYNSKLVTRLINRVMVDGKRGIAANIIY
                     NAFDLIKESTGNDPLEVFEQAMKNVQPVLEVKARRVGGSNYQVPVEVRPERRVTLGLR
                     WVVNYARLRGEHTMEERLAKEIMDAANNTGASVKKREDTHKMADANRAFAHYRW"
     gene            27058..29145
                     /gene="fusA"
                     /locus_tag="ACG8LA_000938"
     CDS             27058..29145
                     /gene="fusA"
                     /locus_tag="ACG8LA_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HFQ0203254.1"
                     /translation="MTREFSLQNTRNIGIMAHIDAGKTTATERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWKGHRINIIDTPGHVDFTVEVERSLRVLDGA
                     VTVLDAQSGVEPQTETVWRQATTYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGAEDDFTGIIDLVTMKAEMYTNDLGTEIEETEIPEEYRELAEEWREKLVEAV
                     AETDEELTLKYLEGEEITEAELKEGIRRATVNVEFYPVLCGSAFKNKGVQLLLDAVLD
                     YLPSPLDIPAIKGIDPKTDEEVERPADDSAPFSALAFKVMTDPFVGRLTFFRVYSGVL
                     QSGSYVQNATKGKRERVGRILQMHANSRSEISEVYAGDIAAAVGLKDTTTGDTLCDEK
                     SLVILESMEFPEPVIQVAIEPKSKADQDKMGVALQKLSEEDPTFRAETNVETGETIIA
                     GMGELHLDIIVDRMRREFKVEANVGAPQVSYRETFRAGTQAEGKFVRQSGGKGQYGHV
                     WIEFTPNEEGAGFEFENAIVGGVVPREYIPAVETGLKDAMENGVLAGYPLVDIKAKLY
                     DGSYHDVDSNETAFRVAASMALRAAAKKANPVILEPIMAVEVVIPEDYLGDVMGHVTA
                     RRGRVEGMEARAGGQQVVRAMVPLAEMFGYATTLRSATQGRGTFTMTFDHYEDVPKSV
                     QEEIIKKNGGKAE"
     gene            29317..30504
                     /gene="tuf"
                     /locus_tag="ACG8LA_000939"
     CDS             29317..30504
                     /gene="tuf"
                     /locus_tag="ACG8LA_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HFQ0203255.1"
                     /translation="MAKEKFDRSKPHVNIGTIGHVDHGKTTLTAAITTVLSKKNGGQA
                     MAYDQIDGAPEERERGITISTAHVEYETDTRHYAHVDCPGHADYVKNMITGAAQMDGA
                     ILVVSAADGPMPQTREHILLSRQVGVPYIVVFLNKVDMVDDEELLELVEMEVRDLLTE
                     YEFPGDDVPVVAGSALKALEGDASYEEKILELMAAVDEYIPTPERDNDKPFMMPVEDV
                     FSITGRGTVATGRVERGQVRVGDEVEVVGIAEETSKTTVTGVEMFRKLLDYAEAGDNI
                     GALLRGVAREDIQRGQVLAKPGTITPHTKFSAEVYVLTKEEGGRHTPFFTNYRPQFYF
                     RTTDVTGVVELPEGTEMVMPGDNVTMEVELIHPIAIENGTKFSIREGGRTVGAGVVTE
                     IKA"
     gene            30911..31219
                     /gene="rpsJ"
                     /locus_tag="ACG8LA_000940"
     CDS             30911..31219
                     /gene="rpsJ"
                     /locus_tag="ACG8LA_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HFQ0203256.1"
                     /translation="MAKQKIRIRLKAYEHRILDQSADKIVETAKRTGASVSGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTPKTVDALMKLDLPSGVNIEIKL
                     "
     gene            31250..31879
                     /gene="rplC"
                     /locus_tag="ACG8LA_000941"
     CDS             31250..31879
                     /gene="rplC"
                     /locus_tag="ACG8LA_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HFQ0203257.1"
                     /translation="MTKGILGKKVGMTQIFTESGELIPVTVVEATPNVVLQVKTMETD
                     GYEAIQVGYQDMREVLSNKPAKGHVAKANTAPKRFIREFKNVELGEYEVGKEITVDVF
                     QAGDIIDVTGTTKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKNKRL
                     AGRMGGNRVTIQNLEVVRVDAERNVILIKGNVPGAKKSLITIKSAVKAK"
     gene            31907..32530
                     /gene="rplD"
                     /locus_tag="ACG8LA_000942"
     CDS             31907..32530
                     /gene="rplD"
                     /locus_tag="ACG8LA_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HFQ0203258.1"
                     /translation="MPNVALFKQDGSQNGEITLNEEIFGIEPNESVVYDAIVMQRASL
                     RQGTHAVKNRSAVRGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYSYKLP
                     KKVRRLAMKSVLSEKVAENNLVAIEGLNFDAPKTKEFKQVLANLSIDSKVLVVLEKGN
                     DFAALSARNLPNVSVVTSDNVSVLDVVSNTKVLATQTALTQIEEVLA"
     gene            32530..32820
                     /gene="rplW"
                     /locus_tag="ACG8LA_000943"
     CDS             32530..32820
                     /gene="rplW"
                     /locus_tag="ACG8LA_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HFQ0203259.1"
                     /translation="MNLLDVIKRPVITEKSMLAMDDKKYTFEVDTRANKTLVKQAVEA
                     AFDVKVKNVNIVNVRAKFKRMGKYAGYTKKRRKAIVTLTEDSKEIQLFEAAE"
     gene            32859..33692
                     /gene="rplB"
                     /locus_tag="ACG8LA_000944"
     CDS             32859..33692
                     /gene="rplB"
                     /locus_tag="ACG8LA_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010756442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HFQ0203260.1"
                     /translation="MAIKKYKPTSNGRRNMTGSDFAEITTSTPEKSLLQPLKNHAGRN
                     NNGRITVRHQGGGHKRQYRVIDFKRNKDNVVATVQTIEYDPNRSANIALVHYEDGVKA
                     YILAPKGLEVGMKLVSGPEADIKVGNALPLENIPVGTVIHNIEMKPGKGGQLIRSAGT
                     SAQVLGKEGKYVLIRLNSGEVRMILAACRATIGSVGNEQHELINIGKAGRSRWMRKRP
                     TVRGSVMNPNDHPHGGGEGKAPIGRKAPVSPWGQPALGYKTRNKKAKSDKLIVRRRKN
                     K"
     gene            33735..34013
                     /gene="rpsS"
                     /locus_tag="ACG8LA_000945"
     CDS             33735..34013
                     /gene="rpsS"
                     /locus_tag="ACG8LA_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HFQ0203261.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQAGVEKKKVIKTWSRRSTVFPSF
                     VGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYRGHAADDKKTKR"
     gene            34036..34383
                     /gene="rplV"
                     /locus_tag="ACG8LA_000946"
     CDS             34036..34383
                     /gene="rplV"
                     /locus_tag="ACG8LA_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003701308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HFQ0203262.1"
                     /translation="MAEQITSAKATAKTVRTSPRKARLVIDLIRGKSVADAISILKFT
                     PNKSAGIIEKVLMSAVANAENNFDLDVENLVVSEAFVNEGPTMKRFRPRAKGSASPIN
                     KRTSHITVVVSEK"
     gene            34397..35053
                     /gene="rpsC"
                     /locus_tag="ACG8LA_000947"
     CDS             34397..35053
                     /gene="rpsC"
                     /locus_tag="ACG8LA_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HFQ0203263.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYAEFLHEDLRIRKFIST
                     KLADAAVSTVEIERATGRVNISIHTAKPGMVIGKGGSEVESLRKELNKLTGKRIHINI
                     VEIKKPDLDAKLVGEGIARQLENRVAFRRAQKQAIQRSMRAGAQGIKTQVSGRLNGAD
                     IARSEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEILPTKKNTEKGGK
                     "
     gene            35056..35490
                     /gene="rplP"
                     /locus_tag="ACG8LA_000948"
     CDS             35056..35490
                     /gene="rplP"
                     /locus_tag="ACG8LA_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011375443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HFQ0203264.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQAVDSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKI
                     MFEIAGVPEEVAREALRLASHKLPMKTKIVKREEMGGESNEG"
     gene            35480..35668
                     /gene="rpmC"
                     /locus_tag="ACG8LA_000949"
     CDS             35480..35668
                     /gene="rpmC"
                     /locus_tag="ACG8LA_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HFQ0203265.1"
                     /translation="MKVKEIRELTTAEMLDQEKQLKEELFNLRFQLATGQLENTARIK
                     EVRKSIARIKTVLREQAK"
     gene            35693..35959
                     /gene="rpsQ"
                     /locus_tag="ACG8LA_000950"
     CDS             35693..35959
                     /gene="rpsQ"
                     /locus_tag="ACG8LA_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HFQ0203266.1"
                     /translation="MTEGRNQRKVYQGRVVSDKMDKTITVAVETKKNHPIYGKRMNYS
                     KKYKVHDENNTAKVGDIVRIMETRPLSATKRFRLLEVVEEAVII"
     gene            36017..36385
                     /gene="rplN"
                     /locus_tag="ACG8LA_000951"
     CDS             36017..36385
                     /gene="rplN"
                     /locus_tag="ACG8LA_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HFQ0203267.1"
                     /translation="MIQAESRLKVADNSGAREILTIKVLGGSGRKTANIGDVIVATVK
                     QATPGGVVKKGDVVKAVIVRTKSGARRTDGSYIKFDENAAVIIRDDKSPRGTRIFGPV
                     ARELRENNFMKIVSLAPEVL"
     gene            36422..36730
                     /gene="rplX"
                     /locus_tag="ACG8LA_000952"
     CDS             36422..36730
                     /gene="rplX"
                     /locus_tag="ACG8LA_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HFQ0203268.1"
                     /translation="MFVKKGDKVKVITGKDKNKEGVVLAAFPKKDKVIVEGVNVVKKH
                     QKPSQAAPQGGIVEMEAPIHVSNVMVVDSTGVAGRVGYKEVDGKKVRVSKKTGEVLDK
                     "
     gene            36758..37297
                     /gene="rplE"
                     /locus_tag="ACG8LA_000953"
     CDS             36758..37297
                     /gene="rplE"
                     /locus_tag="ACG8LA_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016185989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HFQ0203269.1"
                     /translation="MNRLKEKYLKEVTPSLMEKFNYSSVMQTPKVEKIVINMGVGDAV
                     SNAKNLDKAVEELTLITGQKPMITKAKKSIAGFRLREGMPIGAKVTLRGERMYEFLDK
                     LVSVSLPRVRDFHGVSKKAFDGRGNYTLGIKEQLIFPEVDYDLVDKVRGMDIVIVTTA
                     NSDEESRELLTQLGMPFQK"
     gene            37316..37501
                     /locus_tag="ACG8LA_000954"
     CDS             37316..37501
                     /locus_tag="ACG8LA_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011245027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HFQ0203270.1"
                     /translation="MAKKSMIAKNKRPAKFSTQAYTRCERCGRPHSVYRKFHLCRICF
                     RELAYKGQIPGVKKASW"
     gene            37537..37935
                     /gene="rpsH"
                     /locus_tag="ACG8LA_000955"
     CDS             37537..37935
                     /gene="rpsH"
                     /locus_tag="ACG8LA_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010742763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HFQ0203271.1"
                     /translation="MVMTDPIADFLTRIRNANMVKHESLEVPASKIKRDIAEILKREG
                     FVRDVEYIEDDKQGVIRVFLKFGKNGERVITNLKRISKPGLRAYVKADEVPKVLNGLG
                     IAIISTSEGVVTDKEAREKNIGGEVIAYVW"
     gene            37967..38503
                     /gene="rplF"
                     /locus_tag="ACG8LA_000956"
     CDS             37967..38503
                     /gene="rplF"
                     /locus_tag="ACG8LA_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HFQ0203272.1"
                     /translation="MSRIGNKVVVIPEGVTVTQDGNNVTVKGPKGELTRTFSADIKMN
                     IEGNEVTFTRPNDSKEMKTIHGTTRANFNNMVVGVSEGFQKALELIGVGYRAQLQGSK
                     LVLNVGYSHPVEITPPAGVTVEVPANTQVIVKGANKEEVGELAANIRGTRPPEPYKGK
                     GIRYVGEYVRRKEGKTGK"
     gene            38664..39020
                     /gene="rplR"
                     /locus_tag="ACG8LA_000957"
     CDS             38664..39020
                     /gene="rplR"
                     /locus_tag="ACG8LA_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014125626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HFQ0203273.1"
                     /translation="MITKPDKNKTRQKRHRRVRNNISGTAERPRLNVFRSNKNIYAQI
                     IDDVAGVTLASASTLDKEISGGTKTEAAQAVGKLVAERAAEKGIKVVVFDRGGYLYHG
                     RVQALAEAARENGLEF"
     gene            39041..39541
                     /gene="rpsE"
                     /locus_tag="ACG8LA_000958"
     CDS             39041..39541
                     /gene="rpsE"
                     /locus_tag="ACG8LA_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HFQ0203274.1"
                     /translation="MVYIDPKHLELEDRVVAINRVTKVVKGGRRLRFAALVVVGDKNG
                     HVGFGTGKAQEVPEAIRKAIEDAKKNLVEVPMVGSTIPHEVIGAFSGGRILMKPAVEG
                     SGVAAGGPVRAVLELAGVADITSKSLGSNTPINVVRATVEGLKQLKRAEEVAELRGKS
                     VEELIG"
     gene            39556..39735
                     /gene="rpmD"
                     /locus_tag="ACG8LA_000959"
     CDS             39556..39735
                     /gene="rpmD"
                     /locus_tag="ACG8LA_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HFQ0203275.1"
                     /translation="MAELKVTLKRSIIGRPQNQRDTVKALGLTKINSSVVKPSNEAIK
                     GMINTVSHLVDVEEI"
     gene            39779..40219
                     /gene="rplO"
                     /locus_tag="ACG8LA_000960"
     CDS             39779..40219
                     /gene="rplO"
                     /locus_tag="ACG8LA_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HFQ0203276.1"
                     /translation="MKLHELKPAEGSRQVRNRVGRGTSSGNGKTAGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNVNRKDYAVINLDVLNRFEDGAEVTPVALVEAGIV
                     KNEKAGIKVLANGELNKKLTVKAAKFSKAAQEAIEAAGGSIEVI"
     gene            40219..41514
                     /gene="secY"
                     /locus_tag="ACG8LA_000961"
     CDS             40219..41514
                     /gene="secY"
                     /locus_tag="ACG8LA_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HFQ0203277.1"
                     /translation="MFRLLKDAFKVKDIRSKILFTVFVLFVFRLGAHITVPGVNAASL
                     QNLSSLPFFNMLNLVSGSAMQNFSIFSMGVSPYITASIVIQLLQMDIVPRFVEWSKQG
                     EVGRKKLNQATRYLTLVLAFIQSVGITAGFNQYAQLGFVNNPNVATYVTIGLILTAGT
                     MFVTWLGEQITEKGIGNGVSMIIFAGIISRLPESIREIYEDYFINIDPSDIWKSAIFV
                     AILLVAVLLIVTFVTFFQQAERKIPIQYTKRVAGAPTSSYLPLKVNAAGVIPVIFASS
                     FIATPNAVLQALSGRFGSENWYKVMMEIFNYNTAPGATIYTILIVAFTFFYAFVQVNP
                     EKLAENLQKQGSYIPSVRPGKGTEEYVSRLLMRLSTVGAVFLGLVALLPIIAQMVWDL
                     PQSIGLGGTSLLIVIGVALETAKQLEGLMLKRKYVGFIE"
     gene            41576..42223
                     /locus_tag="ACG8LA_000962"
     CDS             41576..42223
                     /locus_tag="ACG8LA_000962"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016776 - phosphotransferase activity,
                     phosphate group as acceptor [Evidence IEA];
                     GO_function: GO:0019205 - nucleobase-containing compound
                     kinase activity [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HFQ0203278.1"
                     /translation="MNLILMGLPGAGKGTQAEKIIDAYGIPHISTGDMFRAAMQNETA
                     LGLEAKSYMDKGALVPDEVTNGIVKERLAEPDTEKGFLLDGFPRTLDQAKALDAMLKD
                     LNKKIDAVIDIHVGEEILVERLAGRFICSNCGATYHKIFNPTKVEDTCDRCGGHEFYQ
                     REDDKPETVKNRLAINIKNSEPILAYYKEQGLLNTIDGAREIDAVFADVQKIIEK"
     gene            42414..42632
                     /gene="infA"
                     /locus_tag="ACG8LA_000963"
     CDS             42414..42632
                     /gene="infA"
                     /locus_tag="ACG8LA_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HFQ0203279.1"
                     /translation="MAKEDMIEVEGTVVETLPNAMFKVELENGHQVLATVSGKIRMHY
                     IRILPGDKVTVELSPYDLNRGRITYRFK"
     gene            42665..42781
                     /gene="rpmJ"
                     /locus_tag="ACG8LA_000964"
     CDS             42665..42781
                     /gene="rpmJ"
                     /locus_tag="ACG8LA_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HFQ0203280.1"
                     /translation="MKVRPSVKPMCEHCKVIRRKGRVMVICPANPKHKQRQG"
     gene            42799..43164
                     /gene="rpsM"
                     /locus_tag="ACG8LA_000965"
     CDS             42799..43164
                     /gene="rpsM"
                     /locus_tag="ACG8LA_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HFQ0203281.1"
                     /translation="MARIAGVDIPRDKRVVVSLTYIYGIGNTTAKKILADAGVSEDVR
                     VRELTNEQTDAIRAEVDKLKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGPARAIAGKKK"
     gene            43192..43581
                     /gene="rpsK"
                     /locus_tag="ACG8LA_000966"
     CDS             43192..43581
                     /gene="rpsK"
                     /locus_tag="ACG8LA_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HFQ0203282.1"
                     /translation="MAAKKVNRKRRVKKNIEAGIAHIHSTFNNTIIMITDTHGNALAW
                     SSAGSLGFKGSKKSTPFAAQMAAETATKAAMEHGLKTVEVTVKGPGSGREAAIRSLQA
                     TGLEVTAIRDVTPVPHNGARPPKRRRV"
     gene            43661..44599
                     /locus_tag="ACG8LA_000967"
     CDS             43661..44599
                     /locus_tag="ACG8LA_000967"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010774253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HFQ0203283.1"
                     /translation="MIEFEKPRIAKIDEEKDYGKFIVEPLERGYGTTLGNSLRRILLS
                     SLPGAAITNIQIDGVLHEFSTIKGVREDVTQIILNIKGLALKMYGQEEKTLEIDITGP
                     ATVTAGDIIVDSDVEILNKDMYICSVSEGATFHARLTVKPGRGYVQADENKKEDMPIG
                     VLPVDSIYTPVRRVNYQVENTRVGHREDFDKLTMEIWTDGSIEPLEAMSLSAKIMTEH
                     LDIFVNLTDEAKNAEIMVEKEETQKEKMLEMTIEELDLSVRSYNCLKRAGINTVQELT
                     NKSEPEMIKVRNLGRKSLEEVKAKLHDLGLGLRKED"
     gene            44627..45007
                     /gene="rplQ"
                     /locus_tag="ACG8LA_000968"
     CDS             44627..45007
                     /gene="rplQ"
                     /locus_tag="ACG8LA_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HFQ0203284.1"
                     /translation="MSYRKLGRTSSQRKAMLRDLTTDLLINERIVTTEARAKEVRSTA
                     EKMITLGKRGDLHARRQAAAFVRNEVASVREENEDIVIESALQKLFNDIAPRYAERQG
                     GYTRILKTEPRRGDGAPMVVLELV"
     gene            45279..46118
                     /locus_tag="ACG8LA_000969"
     CDS             45279..46118
                     /locus_tag="ACG8LA_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HFQ0203285.1"
                     /translation="MEPIIELEKINYKYQPDDLRPALKDVSFTIDKGEWIAIIGHNGS
                     GKSTLAKTINGLLLPESGIVKVGNQILDEENIWTIRQMVGMVFQNPDNQFVGSTVEDD
                     VAFGLENQGIPREEMLVRVKDALEKVRMAEFASREPARLSGGQKQRVAIAGVVALRPD
                     IIILDEATSMLDPEGREEVISTIKKIKEESQLTVISITHDIDEAANANRILVMRQGEL
                     VREGTPKEIFSAGPELIDLGLDLPFPEKLKSALKERGVDVPSEYMTEERMVDWLWTSV
                     LNK"
     gene            46094..46963
                     /locus_tag="ACG8LA_000970"
     CDS             46094..46963
                     /locus_tag="ACG8LA_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HFQ0203286.1"
                     /translation="MDIRFEQVDFTYQPNTPFEQRALFDINMTIKENSYTALVGHTGS
                     GKSTLLQHLNALVKPTSGTVHIGERDIQPDTDNKNLKPIRKKVGIVFQFPEAQLFEET
                     VAKDIAFGPKNFGVSEEEALVLAKETLEQVGLDESYLERSPFELSGGQMRRVAIAGVL
                     AMRPEVLVLDEPTAGLDPQGRKEMMEMFWRLHKEQQITIVLVTHLMDDVANFADYVYV
                     LEKGRIVNSGEPQEVFQNIEWLKEKQLGVPTATEFAEELMAKGMNFATLPLTAEELAD
                     AIVHYAGGNAHDE"
     gene            46953..47750
                     /locus_tag="ACG8LA_000971"
     CDS             46953..47750
                     /locus_tag="ACG8LA_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HFQ0203287.1"
                     /translation="MMNKLIFGRYMPGDSLIHRLDPRAKLLASFYFIGIIFLANNWET
                     YLLLAFFTLLSVFLSKVDLKFFIRGIRPLIWLILFTVALQVLFTSGGETYWSWGVFHI
                     TEFGVMNGLFIFCRFVLIIFMSTLLTLTTPPLELSDAIEYLLRPLKAVRFPVHEISLM
                     LSIALRFVPTLMDETEKIMNAQRARGVDFGEGNLVQKMKAVIPLLIPLFVSSFNRAED
                     LATAMEARGYKGGEGRTKYRVLHWHNRDTMVIIAFVLLTVLLIFLRG"
     gene            47953..48699
                     /gene="truA"
                     /locus_tag="ACG8LA_000972"
     CDS             47953..48699
                     /gene="truA"
                     /locus_tag="ACG8LA_000972"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HFQ0203288.1"
                     /translation="MVRYKAIIAYDGTNFNGFQKQPNGRTVQEEVEKTLQKMANGKEI
                     TVFGSGRTDAGVHAIGQVIHFDYPEERPLERMRFALDTQSPEDIAVRQVEIVSEDFHA
                     RYLVKEKTYQFRVDIGKPRSPFRRHYASYFPYPLDLEKIQRALPDLLGTHDFTSFCAS
                     GSSIEDKVRTIYEAKMEVNETKDELLFTFRGNGFLYKMIRILVGTLLKIGNGRLPEDS
                     IPDIIAKKDRNAAGPTAHPEGLYLYEVKYE"
     gene            49363..49557
                     /locus_tag="ACG8LA_000973"
                     /pseudo
     CDS             49363..49557
                     /locus_tag="ACG8LA_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312603.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(49745..50521)
                     /locus_tag="ACG8LA_000974"
     CDS             complement(49745..50521)
                     /locus_tag="ACG8LA_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HFQ0203289.1"
                     /translation="MNIHHIRNATAILDYGGKKFLIDPMLAEKGTLPPFISKGPFPSP
                     RKDQMNPLVDLPMPVEDIINGIDAVIVTHLHLDHWDDIAKEVLPKEIKLFVQDENDAN
                     EIRLYGFKNVEVLREDTVFESIQLVKTKGKHGRGEILNYVGNVCGIVFKHSTEKTLYF
                     TGDTVWYEAVKQTIDQYNPEIIVANAGDNHFLVGESLIMGKDDLYELHKAIPDSTIIA
                     VHMEAVNHWGLSREELKSFNKEKGISEKVLVPEDGDNIFI"
     gene            50644..>50859
                     /locus_tag="ACG8LA_000975"
     CDS             50644..>50859
                     /locus_tag="ACG8LA_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HFQ0203290.1"
                     /translation="MLDQTDINIIEELSKNSRITMKELGEKVHLTGPAVSARVTKLEE
                     SGVIENYTVKLNMEKLGFSIHAFLIIIT"
BASE COUNT        16125 a         9261 c        11046 g        14427 t
ORIGIN      
        1 gttggttttt aatagattta ataagtactg ataatgaaat ttctcctggt tgggaaaacg
       61 aagttggtta ccctgtagaa gaattttttc aagattactt tgcggagtat gccgatagga
      121 taatgagaga ttacgtaaca gataaaactc aagaagtcat caatcaatcc cagtcattaa
      181 atgaattatc tgataaggcg aaagaagaag cagttgccat tatttcttca gggattagtg
      241 actatattga tatgagtggt gaaatcaatt atggcgataa agacaaaatt gtacgcatga
      301 taaaagcttt tatcaaaact tttgatgtga aggcagatct taagtttaat gatacttacc
      361 tagtaggaaa attaattaat atccttggga cagagaaaga tacggaaacg tttatttcct
      421 ctttgtctat gttgtttaca gataagcatt tttcaactca gcttggtgga gaggaactag
      481 tggaaatctt ttaaccatta cgcccagcat taataaaagt atatcaaaaa agtactcctg
      541 atgattttta agattggttt gagaaataat gtgaaaacac tatttttaat gttaattata
      601 gatagagatg aacgcgtcat atggttaaaa gaatgaaaaa gtcaaagata cactgctata
      661 tttcactaag gatatagcag tgtatctttc atgtcgtttc actggcagtt ttttataaaa
      721 ggaggtgtgc atttcagttg cttttctttg gtagttagtt gaatcgttta agaattaacg
      781 gatgtggcag acaggtgctc tgtccaaaaa ccagtaaaat ctttgatggt tccatcttta
      841 tttagctgtg cctgttcaaa tactgttttg tttttaccga atggatcaat tgcaataatt
      901 gttccgatcc ccgcacgttt ggcagcaagt aatcctgagt aagcatcttc gataacaaga
      961 caatcagccg gagctaagct cagtttgtct gccgctttaa gaaaaatatc cggttgcggt
     1021 ttcccaggga aagagccgtc gtcatagaca atcttgtccc agtcaaacca gcgggctaaa
     1081 tcgaaaatat caaaataaaa agcaacattc tctttgacag tagccgtggc aatcgttaat
     1141 ggaatctgtt ggtcagtcag ctggtcaaga gtcgcttcaa gcccttttgt caactgaagc
     1201 tcgttttcat tttgcaagca aagcatacga taatagcttt ctttttcttc tgacaatacg
     1261 gcgatctcag aggcggtcaa atgctctgaa atgaaatgtt tcaaaatctc cgtattcgtc
     1321 cgaccatgaa tattttttaa aatatcctcg tctgataaac catcttttgt atgatcatgt
     1381 atcatatgca gccaagcagc ttcatgcaga tgagagtcca aaaacattgt tccgttgaaa
     1441 tcaaatataa tccctttcat agttacgctc ctatagtggt attttcggtt gaatcagcaa
     1501 tttgcagatc gacatattgt gcatagtgct cttgaacctc ccgcgagatc tggcgatccg
     1561 taatgagcag atcgaaatca tgcaaattat aaaacacata aaaatcatct cgattgaatt
     1621 ttttattatc aacgagtaga tatttcttac gggaattatt tagagcgatc tgctgtgctt
     1681 ctccttcttc ggtactgtaa gtagagatcg cttcgttgtg aacgccattt gaactgataa
     1741 atgcttttgt aaactttagt cttcttaaat tgtcgttggt gatcggtccg acaaatgcgc
     1801 cggtattttt ccggaaatca ccgccaatca gtagaatttc tggtccatct gcttgagcaa
     1861 gaatatcaaa aactggataa ttatttgtaa tgatccgaat tttcttgttc agtaaatgcg
     1921 tcgccaatag ttcgattgtt gtacctggtc ctaagaaaat cgtttctccc tcgtgaatca
     1981 aggaggctgc tgtggcagca atttcttttt tttcttgaat ctgcagagtg gctttttcag
     2041 tgtgagaaag ttcttgatct aaagtgtagg aaagactttg agcccctcca tggacacgca
     2101 gcagcttgcc cgatttttct aattcatcta aatctctgcg aacggtcata tcagaaacat
     2161 ctaattgatt gatgatttca ttaacggtaa ggattccttt tttattgacc atttctacga
     2221 tagtaagcaa tctttctttt ttcaacattg tcttcacctc taatttaagg ataatctatc
     2281 atataaacgg acaacagtca atctaattcg aacaaaagta aacatttagg gtggttttta
     2341 tgtttgttac aatagatttt attgctgttt tctggttttt atgattattt gtgtttgttt
     2401 ttgttgacaa atgttttgga tgcgtttaca atgcaatcag ttagaaagag cgaaaactga
     2461 ttatagattt gaggagagat gtacatgctt aaattaccag aagattttat ttttggcgga
     2521 gccacagcag cctatcaggt tgaaggagcc actaaggaag gtggcaaagg cgctgttgct
     2581 tgggatgact ttttagagga acaagggcga ttcagtcccg atccggcaag tgatttttat
     2641 catcaatatg caaaggacat tgaattgtgt gaacgttttg gtgtaaatgg tctaagatta
     2701 tccattgctt ggagccgcat ttttcctgat ggagctggga aaccaaatcc agaaggaatc
     2761 gctttttatc atcgtgtgtt cgaagaatgt aagaaaagaa acgtaacgcc gtttgtgacg
     2821 ttgcatcatt ttgatacccc taaacgtttg tttgaccatg gagatttttt gaatcgagaa
     2881 acaatagaag catttgtttc ctatgccatt ttttgttttc atgaattcaa agaagtcaag
     2941 gtgtggagta cctttaatga aatctatcca gttgcaacca atcaatattt gttaggtgtt
     3001 ttcccaccag gaatcaaata tgattttaca aagatcgtcg cctgtcttca taatatgatg
     3061 gttgctcatg cccgtgtagt gaactatttc aaagaaaacg aacttccggg tgaaattggt
     3121 gtagttcact cattagagac gaaatatgcg gcaacagacg cgccggaaga taagcatgct
     3181 gcctttttag acgatgcatt gtcgatccgt ttcttattag atgctaccta tttaggctat
     3241 tattcaactg aaaccttgac tgctcttgat gagatatgtg aagcaaatca ggccagctat
     3301 cattttcctg aagaagattt cgttgaattg aaaaaagcat ccacgcgtaa tgactactta
     3361 gggatcaatc actaccaatg ccattttgtc aaagcttacg atggagaaaa tgcaatccat
     3421 cataacggta cgggtgaaaa agggacctct gtttataaag tgaagggaat cggagaacgt
     3481 atttataaag aaggaattcc tcgaactgat tgggactggc tgatttatcc agaaggtcta
     3541 tatgacttgt tgctgcgaat taaaagcgat tacccacatt acaacaaaat ctatatcact
     3601 gagaacggga tggggtataa agatcagttt gaagatggca ttattatgga tcagccgaga
     3661 atcgactatt tgagagtcta tttggaatcc ttaagcaagg cgataacagc cggggtaaat
     3721 gtgaaggggt attttttgtg gtcgcttatg gatcttttct catggacaaa tgggtataac
     3781 aaaaggtatg gcttgtttta tgttgatttt gaaacccaga agcgttaccc aaaagaatca
     3841 gcttactggt acaagttggt cagtgaaacc aaaacgatta tttaataagt gataatggag
     3901 gaagaaaaga tgaataaaga ggaattacaa atgcttggtt ttgagatcgt tgcatattca
     3961 ggcgacgctc gcagtacatt attgaaatta ttgaaagaag taagacaagg aaactttgaa
     4021 catgttgatt cggcgttgaa agaagccgac gaaaatttaa cccttgcaca taattcgcaa
     4081 acaaaaattt tagcggaaga agcatctggg aaagagatgg agatgggatt catttttatc
     4141 catgggcagg atcatttaat gaccacttta ttgctgagag atctgattca agactttatt
     4201 gtactgtaca gacagaatca aggataggag aagaacgcta tggatggaat cattaaacaa
     4261 atcgaaaaag ggaaaccatt ttttgaaaaa atctcacgta atagttattt aggagccgtt
     4321 cgtgacggat ttttaacagc gatgccagct attttatttt caagcatttt cattttgatt
     4381 gctgcggttc ctgagatttt tggttaccaa tggcctgaat ctgtctccac atggctatgg
     4441 aaagtctata attattcgat gggtgttgta gggttactcg tttcagcaac cactgctcgc
     4501 tgcttggctg attcgatgaa tcgtcgctta ccgaaaaaca aagtaatcaa caccacctct
     4561 gtgatgctgg cctctgtggt aagtttcctg ttgttaagcg tctctccgat tgaaggtgga
     4621 ttttcaacgg aatatatggg gacaaaggga ctactggctt cctttgtcgc tgcattttta
     4681 acagttaatt tatataagtt ttgtgtgctg aaagatatta ccattaaaat gcctaaagaa
     4741 gttcctggaa cgatttcgca aaccttccga gatatttttc ctttctcttt ttcagtattt
     4801 gcggccgttt taattgattt aggcattcga caaatcttcc aaatctcatt tgcagaagca
     4861 atcattacgg tgctgcagcc gctatttaca gcagctgacg ggtacttagg aatcgctatt
     4921 atctggggag cgatggcgct gttttggttt gtcggtgttc atggaccgtc gatcgtggag
     4981 ccggcaattg cggcaattat ctatgccaat gtggaaacca atctgcaatt gttcaattcc
     5041 ggtgaacaag cttctaaagt actgacggtg ggtttaggga attttgtagg aactatggga
     5101 ggaactgggg caacattggt tgttcctttt atcttcctac tctttgctaa gtctaagcag
     5161 ttgaaggcag ttgggaaagc ttcctttatt ccagtaagtt tcgctgtcaa cgaaccattg
     5221 ctatttgcgg cacccatgat tttgaaccct tattttttta ttccattttt gttaacacct
     5281 gttgtaaacg tttgcctgtt caagtttttt gtcgatgtat tgggcatgaa cagctttatg
     5341 tacgttttgc cttgggcaac tccagcaccg atcggtttgg ttctaggaac gggcatgggt
     5401 atcttagctt ttgttctagc agcggttcta atcgtcgttg acttcctgat ctatctacca
     5461 ttttgcaaag catacgatgc tgtcttagta gagaaagaag cacaaaaagc agaggtgatc
     5521 gcaaccgagg aaggtgcttc tgccgatgta cgtgaggaag tacctgtggc agcgagtcaa
     5581 gttatcagcg atgcaaataa agaaatcaat gtgttggtac tttgtgctgg cgcagggaca
     5641 agtgcgatgt tagctaatgc tttaaaaaaa ggtgcatctg aatcgaaagc accgatcagt
     5701 gcaatggcgg gtgcttatgg ttctcattac gaaatgctgc aggattttga tatggtggtc
     5761 ttagcaccgc aagtcaattc ttactatgat gatatcaaag aagacaccga tcgcttagga
     5821 atcaagctgg ttgcgacaaa aggagcagaa tatatcggat taacgagaga tcctgaaaaa
     5881 gctgttcagt ttattctgaa ccaatttcaa taaaggagga gccataatga aaatgggaat
     5941 ttggttgcgt aaagctgttt tatttgcagc tgtgttaggg gctttggggg ctgtttcaaa
     6001 aactgttgaa gcatctgcca gcgaatttat tcgcggagca gatatttcga tcctgtcaga
     6061 tatggaaaaa tctggtgcaa aatattatga agacgatatt tcaaaagatg ccttagagat
     6121 tttaaaaaat aatggtgtca actatgttcg actgcgtttg tggcaggatc cttataatag
     6181 taatggagaa agttatggag cagggacaaa tgatctggaa acgacgattg accttgcaaa
     6241 acgagcaaaa aatctgggac ttaaggtgct gctggatttt cactacagtg atttttgggt
     6301 tgatcctggg aaacagaatc ttcctaaagc atggcaaggt ctgacctttg aagaaatgaa
     6361 tacggcattg tacgactata caaagaacgt tctgtcggaa atgaagcagc tggacgttta
     6421 tcctgatatg gttcagatcg gcaatgaact gaatagcgga atgctctggc cttatggcaa
     6481 gtcttgggga gaaggcgggg gagaatttga tcgattggct gcttttttga agtctggtat
     6541 ccaagctgtt cgagacactc aacctaaaac aactccagta atgctccact tagctgatgg
     6601 tggcgataca ggagcattta cttggtggtt tgatgaaatc acgagtcgag gtgtgtcatt
     6661 tgatttaatt ggagtgtcgt attatccgta ttggcacggt tcaatgaatg aacttcaaac
     6721 caatatgaat gcgatcagcc aacggtatgg taaagaagtg atcgtagttg aaacagctta
     6781 tgggcataca acagcgaatg ccgatactat gccaaatgct tttggtgaag ccgaagcagc
     6841 tgcgggggga tatgaaccaa caccgacagg acaagcagag tatttgctgg atcttgccga
     6901 tcggattcag gcagtaccga ataatcgcgg ggcgggcttc ttctattggg aacctctttg
     6961 gtacaacgga aatgtgagtt gggcaacaca agcaggtatg aattatctca gtgttcaatc
     7021 cactatggga aacgaatggg acaaccaagc gatgtttgat tttgctggaa acgccttgcc
     7081 aagcttgcgt gcgtttaaac aagcaggggc gcaaataaat ctagttaaaa atgcaagttt
     7141 cgaaagcgat ggaccaacga ccagtccttc caattggcaa acctggtttc aacaaggaac
     7201 cgctaagggt acgatcaaaa cggaagcggg cacttttttt ggggactaca aactaacttt
     7261 ttggcaggat caagcatacg aggcatcagc ttatcaaaat gttagtggca taagcaaagg
     7321 aacttacaca ttgagtgcct atgtaatgtc tgggggagag tttgatacta atcagttata
     7381 tatcaaaaat tatggtggag cggaactaaa tactgcggtt gttaaaacaa gtgaatggac
     7441 aaaaattaca atcaaagaca ttccaattac aacaggtgtt tgtgaaattg gggtttatag
     7501 caaggcttca ggaaatgctt ggacgaacgt tgattttgtt tcattggtga aacaatagac
     7561 tgcggatcgt ttcgattcaa gatcggaggt tcccttcagc cacatcgtta gcgtagaagg
     7621 caggaatcga acctgcacct cgcctttgcc aaaaataacc agaaacgatt tccagtcatt
     7681 tttaccaaaa cgagtaaagc accagacttc atctacactt tgtattatgc taaagagagt
     7741 tcaacgattt cgtaagaagc aatgaaaaaa ttgcaaaaag ttgtgcagat aacataaagt
     7801 ttgtttaaga aagggtaacc ttagaattcc gtcgtgaata tgatttgagc acttagatgg
     7861 atagaaaaaa gttctcggaa aacagttcgt ttttcgagaa cttcttttta tgataagaat
     7921 gaaacaaatt aacttatatt atagtctctt ttggtaggga accatcttat ttttaatgaa
     7981 aatcaagcat tttagctatt gaagaatgtt gatttatagg gattccccct ccatattatg
     8041 ttggctcttt attcccactc cactgttgct ggtggtttag aagtgatgtc atacacgata
     8101 cggttgacgt gggctacttc gtttacgata cgtacagaga ttttttgcaa gacttcccat
     8161 gggatacggg caaagtcagc ggtcattccg tcgattgaag ttacagcacg gataccgact
     8221 gtgtagtcgt aagtacgtcc gtcacccata acaccgacag agcggatccc tggaagaaca
     8281 gtgaaatatt gccagatatc acggtcaagt ccagcagctg cgatttcttc acgcaagata
     8341 gcatcagatt cgcgtacgat ttctagcttg tcttcagtga tttcgccaag aacacgaata
     8401 ccaagaccag gaccagggaa tggctgacgc caaacgattg aatcaggcat gcctaactga
     8461 gtccctaatt cacggacttc gtctttgaat aatgtgttta atggttcgat caattcaaat
     8521 tgcatatctt ctggcagtcc acctacatta tggtgagatt tgatcgtctg tgctgtttct
     8581 gtaccagatt cgataacgtc agtatacaac gttccttgtg ctaggaaaga gacgccttct
     8641 tcaccagcaa gttttgttgc ttcgtcatca aaaacatata cgaattcatt cccaatgatt
     8701 ttacgttttt gttctgggtc agatacacct ttcaacttgt ctaagaagcg atctcttgca
     8761 ttgactttga tgatgttcaa gccgaatttt ccgcctagac tttccattac ttgttccgct
     8821 tcgcctttgc gtagcagacc gtggtcaaca aagatagatg tcaattggtc accgatcgct
     8881 ttttgtaaaa gaaccccaac gacactagaa tcaacgccac ctgaaagacc aagcaagact
     8941 tttttgtcac caacttgttc acggattttt tctacttgca tatcgataaa gttatccatt
     9001 gtccagttac cttcacagtg acaaacatca aaggcaaagt ggcgcagcaa ttcgattccg
     9061 tattcggaat gacgtacttc tgcatggaat tggataccat aaaaattacg tgttgtgtct
     9121 tggatagaag caatcggaca atctttgctt gttccgactg tttcaaagcc ttcaggaact
     9181 ttagttacca agtcaccatg gctcatccat actgtttgtt gttttggtgt ttctttaaac
     9241 aagacagctt gatcgcttgt tacttctaac aaggctttcc catattcgcg gtttttagca
     9301 ggctctacgg aaccgccaag tttgtacgtg atcaattgca taccatagca aatccctaat
     9361 acaggaatac ctaaattgaa gatctcagga tcgatcccaa atgcattctc atcatataca
     9421 ctgtttggtc cgccagaaag aatgattccc tttggattca tcgcttttac ttcttctgca
     9481 gtaatgcggt ggctcaataa ttcggaaaag actccaagat cacgaatacg tcttgtgatc
     9541 aattggttat actgactacc gtagtctaat acgataatct tttcaacgtt cgtcatatcg
     9601 gcaacgtttg tcaaatttat tacccctatc cctttaaatt ttatctcaaa atagtcaaac
     9661 tattttaaaa tgctaatatt ttcgcatgaa aatcgaatcg atgatatgat tttcagtttt
     9721 atggagaatt atatcggctc ttcctcgtgt aggcaagata tattcctgta aatttttcaa
     9781 attcacattt ttccatacat cttttgccat tttaaaggct tcttcacgat ctccgatagc
     9841 aaaacgataa taataattct ctggattttg gaaagccgta tccagtaacg caccaaaacg
     9901 atccaaatac catttttcga tcagcacggg atcggcatcg acatagacag aaaaatcaaa
     9961 aaagtcgctg acgtagattt gctgattcgc aggtaattga agcgtattga tcccctcaac
    10021 gatcaagata tcaggctgct ggatcaattc gtacttgtct ggaatgatat catacacatc
    10081 atgtgagtaa acaggtactt ttatctcttc ctgaccagat tttacacggt tcaagaaatc
    10141 gatcagcatc tccatatcat aactttcagg aaatccttta cggtccatga ttccacgctc
    10201 ttttaatata cgatttggat aaagaaatcc gtcagtcgtg atcagctgaa cgtttcttcg
    10261 tttgaaggta cgagacaaaa tcgtctgcag cagtctggct gttgtacttt ttccaacggc
    10321 tacacttccg gcgatcccga taataaaagg cggtacttct acgtatttat gaagaaataa
    10381 acctttactc aagaacaaag attcaaattc tttcatataa agataaatca gatgagcaag
    10441 aggtacatag atatctcgaa catcctgcat ggaaatgcgg tcattcaaac ttttgatatt
    10501 atctagttca tcttgtgtca aaggtgcttg cccattacga taaaattctc gccattcttc
    10561 tcttgccaca cggtagtagt tcattggatc attcatatta gcctcctgcg ttctcccatc
    10621 aatggaacta ttttaacaca aaataaacgc aaaccccacc acttaagaga gattgccgat
    10681 ctttttgtat aatctttata atagaaagaa acggagtctt attcttgact tgcgcacgga
    10741 tacataaaag gatagactgt tgtcatgaaa gaaatgagaa ggatggaaga catgacaaat
    10801 cattactatt ctgaacgccc agatacggcg cacgattttg aacaatgggc ttttgagtta
    10861 aaaggcagaa cctttcaatt tgtaacagat tctggtgtat tttcacgtga aacagtggat
    10921 tatggttcac gtgtcctgat tgatgctttc gattgggaag agttacctga tgaaggaaag
    10981 atcttagatg tgggatgcgg gtatggaccg attgggttag ctttggcatt tgcgacacag
    11041 cggtttgttg aaatggtcga cattaatgaa cgagcggtaa gtctagcgca aggaaacgca
    11101 aagcgtaacc aaatcgaaca tgttgatatc catcaatcga atatctatga agcagttcat
    11161 gaagaaacct atgcagctat cgtaagcaat ccgccgatcc gtgctggaaa aaaagttgta
    11221 catgaaattt tgacaggcgc atatcctcgg ttgaagaagg gcggtacact gacaattgtg
    11281 atccagaaga aacaaggagc gccgagtgcg caaaagaaaa tggaagaaac atttggtaat
    11341 gcagaaatcg tcacaaaaga taaaggatat tatatcatca aaagtgtgaa agaataacta
    11401 gctgaaaaat agtggagcga cgaaagagtg gaactgggcg tgcatgtacg ggtacgtatc
    11461 agttcttttt ttgttgagaa gtttttaaaa acaaagaact attttttctt caaaaagaaa
    11521 tagtaggaac agagtcgttg ttttttacga taaaataaat aagatacaga acttgtatag
    11581 aaggctgcca agtcggtaga taaaggaggt ttttatcaaa aaacatactt tccttttttc
    11641 tctattcttt tcttgggggt tttggtacac tgatagggaa tttagataga agggagccaa
    11701 taggatgaag ctgaccatca gagatatcgc agaaatggca ggcgtatcag taacaactgt
    11761 ctcacagatt ttgaataaca aaggaagcag atttagtgat aagacaagaa aaaaagtgtt
    11821 gtcgatcgtg aatgaacatc attataagcc cgattatttc gcttcaaatg tgatcaatcg
    11881 acattcaaag accatcggaa tgatcgtccc tgatgtcact gatttcttct tctccaaact
    11941 gatcgaaggt gtagagagct atttgaatcc tttgggctat gtgatcatgt tatgcaattc
    12001 tcgtcatagc caagaaaatg agatcaagta tttacaagag ctttcccacc gctcagtgga
    12061 cggaatcttg ctggccacac caaatatttt acctgagaaa tatgcattag acagcggttt
    12121 ttatcaaaaa atgccaatca ttttaatcga tcgcggattg aatcgtcggg ataacggacg
    12181 gcttatcgta aaggaatatg agggcgccta tcaagctgtt tcgctgttta ttgaaaatgg
    12241 ccatacgaag atcggcatgc tgaaggaaac cactggatac tatcaattag aagaacgttt
    12301 caacggatat cgtcatgcgc tgaaagatca tggcctgcct tttaatggga aatttgttga
    12361 acatggagag ttgactgtcc aaggtggata tactgcatca aaaaaattac tcaaacataa
    12421 agatatcacg gctatttttt gcgggaatga tgccatggcg atcggatgct atcaggcgat
    12481 cgatgaattg ggcaaaaaaa tcccagaaga tatctcagtc ataggattcg atggattaaa
    12541 gctgtcagaa tacatgattc cgcaattgac gacagtgcag cagccaagtt ttgatattgg
    12601 attttatgct gcacgtttcc tgatcgatac gatcgaattt cctcaaagaa aagttccgaa
    12661 caaagtgttc gaaacaaaat taattattcg tgagagcgta aaagtattga caaagggcta
    12721 actcggcggt atattgctta tgtaagcatt tacaaaggct agttagtgct ttttttattt
    12781 ttagtaaacc agtttactaa agtggtttac ctttcctaaa aataatgtat aataccgaat
    12841 gaagacaagg aggatcaggc aatgcgaatg gtggatctga ttgaaaaaaa gagggatgga
    12901 aacgagctgt cgaaagagga aatcgagtac atcgtcacga actatacgaa tggaaagatt
    12961 ccagattatc aagtcagtgc attattgatg gcaatttttt atcaagacat gacaaatgaa
    13021 gaaatcacga acttaacatt ggcgattgct aattctggtg atgtcatcga tttgagttct
    13081 cttgaaggaa taaaggtaga taagcattcg acaggtggcg ttggtgacac gaccacattg
    13141 attttagccc ccctagtagc tagtgtcgga gtgacagtgg ctaaaatgtc tggacgcggt
    13201 ctaggttaca caggtggtac actagacaag ctagaagcaa ttcccggatt tcagatcgag
    13261 ctttcggatg aagaatttgt acgcattgtt aatgaaagta aagtagcggt aattggtcaa
    13321 tcaggaaact tggcaccggc ggacaaaaaa ttgtatgcct tgcgtgacgt cacagcgacc
    13381 gttgattctc ttccgctgat tgccagttcg attatgagta aaaaaatcgc ggcaggagca
    13441 gatgcaatcg ttttggatgt gaccactgga gacggtgctt tcatgaagaa catcgaagat
    13501 gcaagacgtc tggcaaagac catgacgagc attgggaaac tggctaaccg agaaacagtg
    13561 gcggttatct cagatatgtc agaacctctt ggcgaagcta tcggaaatag tctagaagtt
    13621 gtcgaggcaa tcgaaacatt acaaggaaat ggtccagaag atctagtaga aatgtgctac
    13681 gccttaggaa gccaaatggt tgttcttgct ggcaaagcta agacaaccga tgaagcaaga
    13741 acgttgcttc aagaagctct ggaatcaggt aaagcgttag caaaattcaa agaaatgatc
    13801 caaaatcaag ggggagaccc agcgatcgtg gaacatccag aacgaatttt gactgcacgc
    13861 tacacaatgg agcttcctgc taaacaaagc ggagttgtgt caaaaatcgt ggcaaatgaa
    13921 ttaggaattg ctgcaatgat gctaggtgct gggcgtaaaa ccaaagaaga agatattgat
    13981 cacgctgttg gattgaaact gcataaaaaa attggtgaca ctgtgacaaa aggtgagtca
    14041 ctattgacga tctatagtaa cgacgaagaa atcacttctg tcattgaatt attatataaa
    14101 aatattgaaa ttggtgaatc ggcaatgaag ccaacgttga ttcatgacat catcacagaa
    14161 taaaggaaaa aagcggactt taccgtttta aagaaaaggg gaaaagaaat ggaactaaac
    14221 cgaatgatcg accatactat tttgaaagca gacgcatcta aagaagctgt gatgcaaatt
    14281 atcgaagaag caaaaaaata ccatttttat tctgtctgca tcaatccagc atgggttgcg
    14341 ctagcgaaag aacaattaca aggtgagcca gtagccgtat gtacagtaat cgggtttcct
    14401 ctaggagcaa acacacccga gacaaaagca tttgaaacaa cagatgccat caataacggt
    14461 gcagatgaag tcgatatggt catcaatatc ggtgctttga aatcaaagga tgatcaacaa
    14521 gtccaaaaag atatcgaagc agttgttgaa gcagcaaaag atcgtgcgct tgtcaaagtt
    14581 attattgaaa catcgttatt agatagagaa gaaatcatcc gagcttgcga aatagcaaaa
    14641 gctgcaggcg ctgattttgt caaaacatca actggtttct caacaggcgg agcaaaggta
    14701 gaggatgtcc gtttgatgcg tgaaactgta ggaccagaaa tgggtgtcaa agcttccggc
    14761 ggtatccata acgaagaaga agcaatggca atgatcgaag ctggtgctac aagaatcgga
    14821 acaagcgcag gagtagcaat cgtatctggt tcaactggtg aaggctatta attttttcaa
    14881 aggagaagct catggcagaa ctcaaacaag aatggatcaa cacagctatt gaagcgttag
    14941 ataaagccta tgttccttat tcccattttc cggtaggcgc ttgtctcgta acggaatcag
    15001 gcaagattta tcaaggcatc aacattgaga atgcatcatt tggattaacg aattgtgccg
    15061 agcgcacagc ttttttcaaa gcagtatctg aaggagaaaa aacatttacg catctagtcg
    15121 tagcggggca cacccccgat cctatctctc cttgtggtgc atgtcgacaa gtaatggcag
    15181 aattctgttc ccctgatatg ccggttacgc tagtaggaga caatggtgtg acgaaggcaa
    15241 cgaccgttcg tgcactgctg ccttatgcat ttactgaaaa agatctataa ctcatgttca
    15301 ttcagtcagc tgactgttga aaaataaaac aattatttta ggaggcttta cagaaatgaa
    15361 aaaagcaaaa ttatttggtt taggtgctgt cgcactagca gcagggttat ttttaggtgc
    15421 atgcggcaac aacggctcta ctgattcatc cggtggcaaa agctcatcag acacaacaac
    15481 tgcagcattg atcacagaca caggtggtgt agacgaccgt tcattcaacc agtcagcttg
    15541 ggaaggacta gaaaaatggg ggaaagatca aggactttca cgaggaaatg atggcttcca
    15601 atatttccaa tcttcaaatg aatcagatta catcccaaat attgaccaag cattgaatgc
    15661 tggattcaaa acgatttttg gtattggtta taaactaaaa ccagcgatcc aagaacaagc
    15721 aacaaacaat acaggtacga actttgttat tatcgatgat gtcatcgatg gattagataa
    15781 cgttgtatct gcaactttca aagacaacga agcttcttat cttgcaggtg ttgcagcagc
    15841 ttatacgact gaaacaaacg tagtcggctt tatcggcggt gtaaaaggtg aagtaatcga
    15901 tcgttttgat gctggattca aagccggtgt tgatgcaggt gcgaaagaat taggaaaaga
    15961 aatcaaagta ttgaatcaat atgctggtga cttctctgct ccagataaag gacgttcaat
    16021 tgctcaaggt atgtatgcac aaaacgcaga tatcatcttc catgcttcag gcggtacagg
    16081 taacggtgta ttccaagaag caaaatcatt gaacgaatca ggcgacaaaa aagtttgggt
    16141 tatcggtgtt gaccgcgacc aatcagacga aggcgaatac acattaaacg gcgaaaagaa
    16201 aaacttcaca ttgacatcta cactgaaagc agttggaaca gtagtagaag atttggcaca
    16261 aaaatcagcg gacggtaaat tccctggcgg cgaacacact gtttatggat tgaaagaaga
    16321 cggtgttggt ctaacagaag gacaactttc tgacgaagcg aaaaaagcag ttgatgaagc
    16381 aaaagaaaaa atcatttcag gtgacgtaaa agttccagaa actcctgaag aaaactaaaa
    16441 ccatttctat agccttgtta gacacatgtt tgacaaggct atggtttgat tagaacaaga
    16501 attgttcatt tatccaagct gccttgtgac agtttggata agggaacaac tccctgaagt
    16561 aatgtttgtt tcaaaagaag aacgctcact aagcgtgaat cttagtcaat cgttgcccta
    16621 gatagaaatc gttaggatgt gaaaaaaagg tggttcaaga aaatattgtc atagaaatgc
    16681 agaatattac caaagaattt ggaacattca aggcaaatga caacatcaat ttacaagtaa
    16741 aggcaggaga aattcatgcg ttgcttggag aaaacggtgc tggcaaatct acattgatga
    16801 acgtgctttc cggattatta gagccgacat cagggaaaat tttgatgcgt gggaaagaag
    16861 taaagatcac aagtccgacc aaagccaacc aattagggat tgggatggtc catcagcact
    16921 ttatgcttgt tgatgccttt actgtaacag aaaacatcgt gttgggaagc gagcctagtc
    16981 gcgcagggat gcttgaccat aaaaaagcac gaaaagagat ccaaaaagtt tctgaacagt
    17041 atggattgtc agtcaaccca gatgcttacg ttcgtgatat ttcagttgga atggaacaac
    17101 gggtagaaat tttaaaaaca ctttaccgag gagcagatgt actgattttt gatgagccga
    17161 cagctgtatt gacccctcaa gaaattgatg aattaatcgt gatcatgaag gaattagtca
    17221 aagaaggcaa gtcgatcatt ttgattacgc ataagttaga tgaaatcaaa gcagtagctg
    17281 accgctgtac agttatccgc cgtggaaaag gaatcggtac agtcaacgtt aaagacgtaa
    17341 cctcacaaca attagccgat atgatggttg gaagaacggt ttcattcaaa acgatgaaaa
    17401 aagaagcgaa gcctcaagaa gtcgttttgt ctattgaaaa tctagtggtg aaagaaaatc
    17461 gtggattaga agccgtgaaa aacttgaact tagaggttcg tgctggcgaa gtacttggta
    17521 tcgctggaat cgatggaaac gggcagtcgg agttgatcca agctttgact ggtttgcgaa
    17581 aggcagaaag cggacatatc aagctaaaag gggaagacat cactaataaa aaaccccgaa
    17641 aaatcactga acatggtgta ggacacgtgc cagaagaccg tcataaatac gggttagtcc
    17701 tagatatgac attatctgaa aatatcgcac tacaaaccta tcatcaaaaa ccttacagta
    17761 aaaacggcat gctgaattat tcagtaatga atgaacatgc cagagaattg atcgaagaat
    17821 atgatgttcg aacaacgaat gaacttgttc ccgcaaaagc tttatcaggc ggaaatcagc
    17881 aaaaagcaat tatcgctcgt gaagtcgacc gagatcctga tctgttgatt gttgcaaatc
    17941 caactcgtgg actggatgta ggtgcgatcg aatttattca taaacgtctg atcgaacaaa
    18001 gggacaaata caaagcagtg ttactgatca gtttcgaatt agaagaaatt ttaaatgttt
    18061 cggatcgtat tgctgttatc catgaaggag aaattgtcgg tatcgttgat ccgaaagaaa
    18121 catctgaaaa tgaattaggt ctattgatgg cgggctatac cttagaagaa gcacgaaaag
    18181 agttagaaaa gggggctggc gcacatgaat gatcgcagcg aaaaattccg taatttatta
    18241 gtgcctgtac tttcagttgt tttaggattg atcttaggcg cgatattgat ggctgctttt
    18301 ggttttcagc ccatccaagg ttattcttct atgctagatg cagcccttgg ttcgcaaaga
    18361 gggataggtg aaacgttaag gcaagcaacg ccgttgattt ttacagcatt aggtttttct
    18421 gtagctaact cagctgggtt tttcaatatt gggctttctg gacaagcact ttgcgggtgg
    18481 atcgtcagtg tctgggtggc acttgcgttt ccagatctgc caaaagttgt tttgcttccg
    18541 ttatgcgtga tcttaggtgc cttagctggt gcgatggcag cggctgttcc aggtttactt
    18601 cgagcatttt ttggaacaag tgaagtgatc gtaacaatca tgatgaacta tatcttatta
    18661 tacgtaagca catttgcttt acatgaagtg atgcctgaaa gctatcgctc aagtttggac
    18721 tcttccaata tgatcagtca aaatgcctca ctgcggttac catggttaac acaagctttt
    18781 ggcggctctc gcgtaaactc aggattattt ttagcaatca tcgcgcttat tttcgtttgg
    18841 ctgctgatga agaaaacgac tttaggattt gaaatccgtt ctgttggatt gaatcctttt
    18901 gcttctgagt atgcaggaat gagtagtaaa cgtacgatcg ttttgtcgat ggtcatttct
    18961 ggcgctttgg cagggcttgg cggtgtggtt gaaggattag gaacgtatca aaacttcttt
    19021 gttcaaacga cttcgctatc tattggattt gacggaatgg ctgtttcctt gcttggttct
    19081 ggatcagcaa tcggtattct tttatcagcg atcttgttca gtattttgaa gatcggtgga
    19141 cttggcatgc agacaggagc aggtgttccg tttgagatcg tcaatgtatc gattgctttg
    19201 attatcttct ttgtcgggat caacttcctg attcgtttcg tcatggctaa agtcttccaa
    19261 gggaaaaaac aagaagagat cgttgcgaca atagaatcga aaccaacgaa tcaaaaccat
    19321 gaagggggcg aactataatg tcgactatcg aattaattgc cttgatcctt acttctacac
    19381 tggtttattc aacaccgcta attctaacgt cactaggcgg aactttttct gaacgaagcg
    19441 ggatcgtaaa cgtagggcta gagggaatca tggtcatggg tgcttttagt tccatcgttt
    19501 tcaacttgac gatgagtcca tcacttggtt ctatgacacc atggatcgct attttagtgg
    19561 gtggcgtcgt aggtatccta ttttctctga ttcacgcagt agcaacagtc agtttgcgtg
    19621 ctgaccatat tatcagcggg acagtaatta atctgatggc acctgcttta ggtgttttct
    19681 tgatcaaagc atggtatggt aaaggtcaaa ctgataacat cacgcagaat ctggggtatt
    19741 tttctttccc aggattagca gatattccgg tcattggacc aattttcttt aaaaatacat
    19801 tcttacctgc ttattgtgct attttgattg ctgtcctagc ttgggtgatc atcttcaaga
    19861 cgaaattcgg cttgcgcctc cgttcagttg gtgaaaatcc tcaagctgcc gacacattag
    19921 gtatcaatgt atatgctatg cgttattcag gcgtactgat ttctggcttg ttaggcggta
    19981 tgggcggtgc tgtttttgct cagtcgattt ccggtaactt ttcagctggt acgatcgttg
    20041 gacaagggtt catctccatg gctgctatga tctttggtaa gtggaatcct ttaggggcaa
    20101 tgggtgcctc attgttcttt ggttttgctc aaagcttgag tatcattggc gcacaattac
    20161 cagttatttc ttcgattccg ccagtattgc tgcaaattgc tccatatttg ctgacaatca
    20221 ttgtgctggt tgttttctta gggaaagctt ctggtccaaa agcaaacggg aagaactata
    20281 tcaaatcaaa ataatctttt agcgaataaa aagggtgggt tacgggaagt gtttttcgtc
    20341 tcgccctttt tgttttaaag gcaataaaaa taaaaagaaa gaaggaataa tcatgtttaa
    20401 acgcgtacat ctgatcgtca tggattcagt aggaattgga gaagcaccag atgccgataa
    20461 gttcggtgat gttggttctg atacattagg acacattgcg aaagaagcag gattgaacgt
    20521 tccacattta gagcagcttg gtttaggaac gatccgtcct cttgaaggtg tggaatcagt
    20581 gaaagatcat caaggctatg cgacgaaatt agaagaagtt tctgtaggga aagatacgat
    20641 gacaggccac tgggaaatca tgggattgaa tatcaaaact ccatttcgtg tgtttcctaa
    20701 tggattccct gatgatctga tcaaacaaat cgaagaattt tctggccgta aagtcgtatg
    20761 taacaaacct tatagcggaa cagctgttat tgacgattac ggtgaacacc aaatgaaaac
    20821 aggcgattta attgtatata cttctgccga tcctgtcctt cagatcgcgg cacatgaaga
    20881 aatcattcct ttagaagaat tatatcggat ttgccaattc gttcgtgata taacaaaaga
    20941 tgatccgtat atgattggcc gaatcattgc acgtccgtac gtgggtgaac caggagactt
    21001 cacacgaaca agcaatcgcc atgattatgc gttgaatcca ttcggacaca cagtccttga
    21061 ttctttgaaa gaagcaggaa aggacgtgat tgctgttgga aagatcaacg atattttcaa
    21121 cggacaagga atcactgaat ctgtccgcac gaaaagcaat atggatggcg ttgaccagct
    21181 gctgaaagtt atgaaaaacg atttttcagg aatcagcttt accaatttag tagattttga
    21241 tgcattatac ggtcatcgtc gggatgtagt cggctatgcg catgcgattg aagaatttga
    21301 cttacgaatt ccagaattgc ttgaagcgat ggaagaagac gacttgctaa tgattacagc
    21361 cgatcacgga aacgatccga cgtttactgg taccgatcat acgcgagaat atgtaccgtt
    21421 attggtttac agtaaaaaaa tgaaagaaca aggggcattg cctcaaggat attattcaga
    21481 tatttcagca acgattgctg agaactttag tgtttcttcg actgaaaatg gcgaaagctt
    21541 cttgaaatta ttaaaataat ctttttaaat aggagaaagc aaatgaccaa gttaagcgag
    21601 atgttacaag aaacgaccca gtttatcctt gataaaggag taaaagaaat tgattttggt
    21661 ttgattctag gttcaggatt aggtgaatta gcagatgaaa tcgaagatgc tgtaatgatt
    21721 tcttatgatg agatcccgtt ctttcctgtt tcgacagtag ttgggcatgc aggaaagcta
    21781 gtttatgggt ctctggcagg caagaaagtg ttagccatgc aagggagatt ccactactat
    21841 gaaggtcatt ccatgcaaac agtgacctat ccagtacgtg tgatggccgg actaggggcc
    21901 cattcagtca ttgtgactaa tgcatgtggt ggtgtcaacg aatcatttgt accaggagat
    21961 ttgatgctga ttaccgatca tatcaatttt actggtgaaa atcctttgat cggtccgaat
    22021 gaagatgcaa tgggccctag atttccagat atgagtcaag cttatacgcc tgactatcaa
    22081 gcaacagcaa aagcagcagc agaaaaacta ggtttggatc ttaaagaagg cgtatatatg
    22141 ggctattctg gaccaactta tgaaacgcct gcggagatcc gaatgtctcg gacaatagga
    22201 gccgatgcag tagggatgtc gactgttcca gaagtcatcg tagcagctca cagcggatta
    22261 aaagtgttag gaatctcttg tattaccaac ttagcagcag gtatgcaagc gaatctgagc
    22321 catgaagaag ttgtagaaac aactcagaga gtcaaacaat cttttaaagc attggttaaa
    22381 gaaacattga cattattgta ataggaggaa caataaaatg agtgtgcata ttgaagcgaa
    22441 agaaggcgag atcgccgata agattttact tccgggagat cctttgcgag ctaaatatat
    22501 tgcggagact tttttggaag atccagtttg ttacaatcag gtacgcggta tgttaggctt
    22561 taccggcaaa tataaaggag aacgtatttc tgttcaagga acaggaatgg gaatgccatc
    22621 agccaccatc tatgcccatg aattgatcca gtcgtatggt gtaaagaaat tgattcgagt
    22681 aggtacatgc ggtgcattgt caaaagacgt ccatgttcgt gatttagtac tagcacaagg
    22741 tgcagcgacc agttcttcga tgatcgaaaa aaatttccaa gcctttcatt ttcctccaat
    22801 cagtgatttc aatctattac tgaaagcata tgagatagct aaagaaaagg gctatacggt
    22861 tcatgtagga aatgttcttt cggaagattc tttctacaaa gatgatttga cagagacgtt
    22921 ccaattagct gaacttggcg ttttaggagt ggaaatggaa gcagcggctc tttattactt
    22981 aggcgcgaaa taccatgtgc agacattaag tttgatgacc gttagcgacc atttgatcac
    23041 cggtgaagaa acaacagctg cagaacgtca atctacgttc aatgaaatga tcgaagtagg
    23101 attggaaaca gcgatagcag aataagaagg aaatgaaaaa gctgccctgc attaagtaat
    23161 aagaacatcc aagcaaaaat agctcctcat gtttttgact tggctggact tattattgca
    23221 aatgtaagct tttgaacacc gtttaccaag aggttgtgaa tctgccgttt aactctgagt
    23281 cacaaggaac aatttcaaaa aacagctttt catgtttgat gaatattgtg acttgtgacc
    23341 gagaagttgg caggagaaaa ccgtttatac gaaaaaaggg actgtgacaa atcgtgtcac
    23401 agtccctttt ttatagtgtt ttttataggt agtatttttt agcaactgtt aagtcatcat
    23461 ttaattcata aacaagtggt tgacctgttg gaatttcaag atccatgatg tcttcgtcag
    23521 agataccttc gatatgttta gctagggcgc gtaatgagtt accatgtgca gctactaaaa
    23581 cagttttgtt gtctagtaat gctggagcaa tttcatcttg ccagaatggc aaagcgcgtt
    23641 ctaatgtcac tttcaagttt tctccaccag gaatatcgcg tttgtctaac attgcgtaac
    23701 gacggtcatt tgctgcagaa ccttcgtcag tttcttccat taatggagga agagtatcgt
    23761 aagaacgacg ccagatgtgc acttgttcgt cgccgtattt ttcagctgtt tcttttttgt
    23821 tcaaaccttg taatttacca tagtgacgtt cgtttaagcg ccatgatttg atttgtggta
    23881 cccaaagttg atctgaatat tctaagatca agttacatgt tttgattgca cgagttaaaa
    23941 cagaagtgta agcaacatca aattcgattc cagcttcttt gattttgcgt ccgccttctt
    24001 ttgcttcttc gattccttct ggtgctagat ttacatcagc ccaaccagta aattggttca
    24061 atgcattcca ttcactaaga ccgtgacgag aaaaaactaa ttttggcatg tttagctctc
    24121 cttttaagat aggtttatat ttctgaaatt ttcagttctg ttttattgta caattttttg
    24181 gaagagattt ccatcgaaaa attagataag attctatgag aaaacaagta gagaatataa
    24241 aaaaacgaac agtgcccacg caactgttcg tttttaggta ttagatgcat aattgctcga
    24301 tttctttttc aggtaaattg atatatttat aacatgttcc aactgaaaca ccgcattttg
    24361 aagaaataaa ttggatcgtt tctttttttt cataatagag acgtcggatt tttttgatcg
    24421 tttttgcatc gatttttggt cttccgccga tttttccttt tttacgagct tcatctaatc
    24481 caactaatgt acgttctttg atcaatgcgc actccatgtt tgctaggttt tccattaatt
    24541 ggaaatagat ttttcccatt tcgcgcgtat cgattccttc atcaagacta atcaagtgca
    24601 gcccgcgatc tttgaataat tgcgtgagtt ctgttaattg ccgcgtagat ttgcctaatc
    24661 gatgaagttg gcaaatgact agtgcatcgc cttgttgcat gtcagcgatc actgactcca
    24721 aatgaacagc agtagaatca ttttgttcca cttcatatgt ctcatggaaa atttcttgac
    24781 aaccaaagtc agataattga tcaacctgag ttgttaaatc aacgtcattt atggttgtgc
    24841 gtgcataacc aataattttc atggtgattc ctttctagca gtgattttct aactggatat
    24901 aacagtaaaa atgtagcata aagtacgtca aaaagatagt tttttcgcaa attttccgct
    24961 gtcttttttt attggatgat caagcagttt ttctttattt acgacggatt gcgtcaagaa
    25021 tctcaacgcc tttttctgag ccgacaacta ctttagaaac catgtttagg aaaagcccat
    25081 gttctactac cccaacaagt tcatctaaat aggtagctaa gctttctggc tgttcgatga
    25141 cttctagatg cagatcaatg atgtaatgac caccatctgt ggttaagact tctccgtttt
    25201 cgtctgtacg caagacgggt tggaatcttt tttcttcaaa aatatgaagt agctgttggg
    25261 agccataagg gatcacttca actgggagtg ggaacttccc aagtttatcg actaatttag
    25321 aagaatcaac gatccaaatc gtttcttttg agtacgtagc gactattttc tcgaaaagca
    25381 aagcagcgcc gccgcctttg atcccttgaa aatcagcact gatttcatca gcaccgtcta
    25441 ttgtcaaatc gactacgggg acttcatcaa tactctttaa cggtattcct aatttttccg
    25501 cttgttcttt tgtcgcattt gaagtagtaa ctcctgtgat acgtaaacct tcttcacgca
    25561 tacggcgacc aatctcttct accatataat aggcggttga accggtcccg agacctacga
    25621 tcatcccgtc ctttacgaat ttcgcggctt caatgccagc taattgtttt aaattcatct
    25681 ttgcgtccac ctttttttag tttgagcatc gtgctttcct cactatttta gcgtgattta
    25741 cggtaaaaag ataccattct tttttattcc aataaagctt tttcaaaaaa aattgcatct
    25801 cttgttgaca tgttttttca ttcgtgatat tctaacaaag gtgctttatc tacaggtttc
    25861 tgtgaagaaa cgtgctgact gtttatcaaa gcatatttga taaggatgca gacattgcat
    25921 ttatttttta tcacaaaaaa agaaccacct ggatgtgtgg aactagacgc aaatcgtggg
    25981 aaggaggaaa caaggaatgc ctacaattaa ccaattagta cgtaaacctc gtaaatcaaa
    26041 ggtggaaaaa tctaattcac ctgctttgaa caaaggatat aacagcttta agaaaactca
    26101 aactaacgta aactcacctc aaaaacgtgg ggtagcaact cgtgtgggta caatgacacc
    26161 taaaaaaccg aactcagctt tacgtaaata tgcacgtgtt cgtttgtcaa acttaattga
    26221 agttactgct tatatcccag ggattggtca taacttacaa gaacacagtg ttgtattatt
    26281 acgcggtggt cgtgtaaaag acttaccagg ggtacgttac catatcgttc gcggtgcttt
    26341 agatactgct ggtgttaacg accgtaaaca aagccgttct aaatacggaa ctaaaaaacc
    26401 taaagcttaa ttttaattat taaacaaatg aaacttgctt ctactatata gaagtaatta
    26461 ctatgaacaa tatttcggaa ggaggagtta cggatgccac gtaaaggtcc tgttgcaaaa
    26521 cgtgatgttt taccagatcc tatttataac tcaaaattag taactcgctt gatcaaccgt
    26581 gtaatggttg acggaaaacg cgggattgca gctaacatta tctataatgc ctttgacttg
    26641 atcaaagaat ctacaggtaa cgatccatta gaagtgtttg aacaagcaat gaaaaacgtt
    26701 caacctgttc ttgaagttaa agcacgtcgt gttgggggtt caaactacca agtaccagtt
    26761 gaagttcgcc ctgaacgccg cgttactcta ggtcttcgtt gggtagtaaa ctacgctcgc
    26821 ttgcgcggtg aacacacaat ggaagaacgc ttagcaaaag aaatcatgga tgctgcaaac
    26881 aacacaggtg cttctgttaa aaaacgtgaa gacactcata aaatggctga tgccaaccgt
    26941 gcgtttgctc actatcgctg gtaagattct ctctgtttgg tcggctttta taagtcgacc
    27001 tcagatagtg tccttatttt tagcaactag atagtaaaga gaggagaaac aaggagaatg
    27061 accagagaat tttctttaca aaacactcgt aatatcggta tcatggccca catcgatgct
    27121 ggtaaaacga ctgctactga acgtatcttg tactatactg gtaaaatcca taaaattggt
    27181 gaaactcatg aaggagcttc acaaatggac tggatggaac aagaacaaga acgtggtatt
    27241 acgatcactt ctgctgctac tacagcacaa tggaagggtc accgaatcaa catcatcgac
    27301 acaccaggac acgtagactt cacagttgaa gttgaacgtt cattgcgtgt acttgatggt
    27361 gctgtaactg ttcttgatgc acaatcaggt gttgaacctc aaactgaaac agtttggcgt
    27421 caagcaacaa cttatggtgt acctcgtatc gtatttgcaa acaaaatgga caagatcggt
    27481 gctgacttct tatattcagt atcaacttta catgaccgtt tgcaagcaaa cgctcaccca
    27541 atccaattac caattggtgc ggaagacgac ttcacaggaa ttatcgacct tgtaacaatg
    27601 aaggctgaaa tgtatacaaa cgatcttgga acagagatcg aagaaacaga aattcctgaa
    27661 gaataccgcg aattagctga agaatggcgc gaaaaattgg ttgaagctgt agctgaaact
    27721 gatgaagaac ttactttgaa atacttagaa ggtgaagaaa tcactgaagc tgagttaaaa
    27781 gaaggtatcc gccgcgcaac agttaacgta gaattctacc cagtactatg tggttcagca
    27841 tttaagaaca aaggggttca attactattg gacgctgttc ttgattactt gccatcaccg
    27901 ttagatatcc cagctatcaa agggattgac cctaaaactg atgaagaagt agaacgtcct
    27961 gcagacgaca gcgctccttt ctcagcttta gcatttaaag ttatgactga cccattcgta
    28021 ggtcgtttaa ctttcttccg tgtgtactct ggtgttttac aatcaggttc atacgtacaa
    28081 aacgcaacaa aaggcaaacg tgaacgtgtt ggtcgtatcc tacagatgca tgccaactct
    28141 cgttcagaaa tctctgaagt ttacgctgga gatatcgctg ctgctgttgg tttgaaagac
    28201 acaactactg gggacacact atgtgatgaa aagagtctag ttattcttga atccatggaa
    28261 ttcccagaac cagttatcca agtcgctatt gaacctaaat caaaagctga ccaagataaa
    28321 atgggtgtgg ctttacaaaa actatctgaa gaagatccta ctttccgtgc tgaaacaaac
    28381 gtggaaacag gcgaaacaat catcgctggt atgggtgaac ttcacttaga tatcatcgtt
    28441 gaccgtatgc gtcgtgaatt caaagttgaa gctaacgtag gtgcgcctca agtatcttac
    28501 cgtgaaactt tccgtgctgg cactcaagcc gaaggtaagt ttgtacgtca gtctggtggt
    28561 aaaggtcaat acggtcacgt atggattgaa tttacaccaa atgaagaagg tgctggtttc
    28621 gaatttgaaa atgcgatcgt cggtggggtt gttcctcgtg aatacattcc agctgttgaa
    28681 actggtttga aagatgctat ggaaaatggt gtcttagctg gctatccatt agtagatatc
    28741 aaagctaaac tttacgatgg ttcataccat gatgtcgatt caaatgaaac tgccttccgt
    28801 gttgctgctt ctatggcatt acgtgcagca gctaagaaag ctaatccagt aatccttgaa
    28861 ccaatcatgg ctgtagaagt tgttatccct gaagattatt taggtgatgt tatgggtcac
    28921 gtaactgctc gtcgtggacg tgttgaaggt atggaagctc gcgctggcgg ccaacaagtt
    28981 gttcgtgcga tggttccact tgctgaaatg tttggttatg ctacaactct tcgttctgct
    29041 actcaaggtc gtggtacatt tacaatgaca tttgaccact acgaagatgt accaaaatca
    29101 gtacaagaag aaatcattaa gaaaaacggc ggaaaagctg aataatttct taaaaccgga
    29161 tagtcctgca aagagattat ccaaagagac tatattttta atatagtttc gtgtaaaata
    29221 attatcgatg atatgggcat gtggtgtacc ttgtgtacat catataccta tcagacaaat
    29281 aaaaaatata ttgtattttt aggaggacat tttaaaatgg caaaagaaaa atttgaccgt
    29341 tctaaaccac acgttaacat tggtactatc ggacacgttg accatggtaa aactacatta
    29401 acagctgcaa tcacaactgt actatctaag aaaaacggcg gccaagctat ggcttacgat
    29461 caaatcgatg gtgctccaga agaacgcgaa cgcggaatca caatctcaac agctcacgtt
    29521 gagtatgaaa cagatacacg ccactacgct cacgttgact gcccaggaca cgcggattac
    29581 gttaaaaaca tgatcactgg tgctgctcaa atggacggag ctatcttggt agtttctgct
    29641 gctgacggcc caatgcctca aactcgtgaa cacatcctat tgtctcgtca agttggtgtt
    29701 ccttacatcg ttgtattctt gaacaaagta gacatggttg atgacgaaga attactagaa
    29761 ttagttgaaa tggaagttcg tgacctatta acagaatacg aattccctgg tgacgatgtt
    29821 cctgtagttg ctggatcagc tttgaaagct ctagaaggcg acgcttcata cgaagaaaaa
    29881 attcttgaat taatggctgc agttgacgaa tacatcccaa ctccagaacg tgacaacgac
    29941 aaaccattca tgatgccagt tgaagacgtg ttctcaatta ctggacgtgg tactgttgct
    30001 acaggtcgtg ttgaacgtgg acaagttcgc gttggtgacg aagttgaagt tgttggtatt
    30061 gctgaagaaa cttcaaaaac aacagttact ggtgttgaaa tgttccgtaa attgttagac
    30121 tacgctgaag ctggagacaa cattggtgct ttactacgtg gtgttgcacg tgaagacatc
    30181 caacgtggac aagttttagc taaaccaggt acaatcacac ctcatacaaa attctctgca
    30241 gaagtatacg tgttgacaaa agaagaaggt ggacgtcata ctccattctt cactaactac
    30301 cgtccacaat tctacttccg tacaactgac gtaacaggtg ttgttgaatt accagaagga
    30361 actgaaatgg ttatgcctgg cgacaacgta acaatggaag ttgaattaat ccacccaatc
    30421 gctatcgaaa acggtactaa attctcaatc cgtgaaggcg gacgtacagt tggtgccggt
    30481 gtcgttacag aaatcaaagc ttaattcact taagttttaa agtaaagcaa catttattcg
    30541 gacgtaatcg ctcggaacga aggtcttagg atctttgttc cgagcttttt tatttattgc
    30601 aggatcagga aaaaagacag gagtattata aatagaagaa acacgaaata aaagagtcag
    30661 tattttctaa atgaaacttt atgaaaacaa aatgtttttt acaagaaaaa gccttgcttt
    30721 gtgagtttat atatattata atgacaaagg tgcgtttact ttagtgaatt gcacagacgt
    30781 aatcagaatg atttcgtcgg ctaagaaacg agaggttgcg acacgcccgg acgctttgcc
    30841 acgaacgagc gtgacggaaa ttttcgtgga gctatgtcta cttttcaaaa taggcgaagg
    30901 agggaacaag atggcaaaac aaaaaattcg tatccgttta aaagcgtatg aacaccgtat
    30961 tttagatcaa tcagcggata aaatcgtgga aactgcaaaa agaactggag ctagcgtgtc
    31021 tggtccaatt ccattaccaa ctgaacgcag tctttacaca atcatccgtg cgactcataa
    31081 atacaaagat tcacgcgaac aattcgaaat gcgtacacac aaacgtctta tcgacattgt
    31141 gaacccaaca ccaaaaactg ttgatgcttt gatgaagcta gacttaccat ctggtgtaaa
    31201 catcgaaatc aaattataaa actaaaacaa aaataatgga ggtgtactca tgaccaaagg
    31261 aatcttaggg aaaaaagtgg gaatgacaca aatcttcact gaatctggtg aattaattcc
    31321 agtaactgtt gtagaagcta ctccaaacgt agtactacaa gtgaaaacaa tggaaacgga
    31381 tggctacgaa gctattcaag ttggttacca agatatgcgt gaagttttat caaacaaacc
    31441 tgcgaaaggt catgttgcaa aagcaaacac ggctcctaag cgcttcattc gtgaattcaa
    31501 aaatgttgag ctaggagaat atgaagtagg aaaagaaatt acagtagatg ttttccaagc
    31561 aggagacatt attgatgtaa caggtactac gaaaggtaaa ggattccaag gggttatcaa
    31621 acgccacgga caaagccgcg gaccaatggc tcacggttct cgttaccatc gtcgtcctgg
    31681 gtcaatgggt ccagttgcac ctaaccgtgt atttaaaaac aaacgtcttg ctggccgtat
    31741 gggtggcaac cgcgtaacta tccaaaactt ggaagttgta cgtgtcgatg cagaaagaaa
    31801 tgttatcttg atcaaaggta atgttcctgg agctaaaaaa tctttaatta ctatcaaatc
    31861 agctgtgaaa gctaaataat tgtaggaaga aaggaggaac taaggaatgc cgaatgtagc
    31921 attattcaaa caagatggaa gccaaaacgg tgaaatcaca cttaacgaag aaatcttcgg
    31981 aattgaacct aatgaaagtg ttgtttacga tgcaatcgta atgcaacgtg cgtcattaag
    32041 acaaggaaca cacgcggtta aaaaccgtag cgctgttcgc ggcggcggac gtaaaccatg
    32101 gcgtcaaaaa ggaacaggtc gtgcacgtca aggatctatc cgctcaccac aatggcgtgg
    32161 aggtggcgta gtctttggac caacaccacg ttcttacagc tacaaacttc ctaaaaaagt
    32221 tcgtcgttta gcaatgaaat ctgtattgtc agaaaaagtt gctgaaaaca acttggtagc
    32281 aatcgaaggc ttgaacttcg acgcaccaaa aacaaaagaa ttcaaacaag ttcttgctaa
    32341 cttatctatc gactctaaag tattggttgt tctagaaaaa ggtaacgact ttgctgcttt
    32401 atcagcacgt aacttaccaa acgtttctgt agtaacttct gataatgtga gtgtgctaga
    32461 cgttgtatca aatacaaaag tgttagcaac acaaactgct cttactcaaa ttgaggaggt
    32521 gcttgcataa tgaacttact agacgtaatc aaacgcccag tgatcactga aaaatcaatg
    32581 cttgccatgg atgacaagaa atacactttt gaagtggaca ctcgcgcaaa caaaacttta
    32641 gtaaaacaag cggtagaagc tgcttttgac gttaaagtca aaaacgtgaa catcgtgaac
    32701 gtacgtgcga aattcaaacg tatgggcaaa tatgcaggat atacaaaaaa acgtcgcaaa
    32761 gcgatcgtta cattgactga agattcaaaa gaaatccaat tattcgaagc tgctgaataa
    32821 gcactaatag ataactcatt aaattaggag ggaaaaacgt ggcgattaaa aagtacaaac
    32881 ctacctcaaa tggtcgtcgt aacatgacag gttctgattt tgctgaaatc acaacatcaa
    32941 cacctgaaaa atcattgtta caaccattga aaaaccatgc tggacgtaac aacaacggcc
    33001 gcatcactgt acgtcatcaa ggtggcggac acaaacgcca atatcgcgtg atcgacttca
    33061 aacgtaacaa agataacgtt gttgcaactg ttcaaacgat cgaatatgat ccaaaccgtt
    33121 cagctaacat cgcgttagta cactatgaag atggagtgaa agcttacatc ttagcaccta
    33181 aaggactaga agtgggtatg aaacttgttt caggtccaga agcagatatc aaagtcggaa
    33241 atgctcttcc attagaaaac attccagttg gtactgttat ccacaacatt gaaatgaaac
    33301 ctggtaaagg tggacaattg atccgttctg ctggtacaag tgctcaagta cttggtaaag
    33361 aaggcaaata cgtattgatc cgcttgaact ctggtgaagt tcgtatgatc ttagctgcat
    33421 gccgtgctac aatcggttct gtaggtaacg aacaacacga attaatcaac atcggtaaag
    33481 ctggacgctc tcgttggatg cgtaaacgcc caactgtacg tggtagcgta atgaacccta
    33541 atgatcaccc acacggtggt ggtgaaggta aagctcctat cggacgtaaa gcaccagttt
    33601 ctccttgggg tcaaccagct cttggttaca aaactcgtaa caaaaaagct aaatcagaca
    33661 aacttattgt tcgtcgtcgc aaaaataaat aattactttg accatgtgtc gcacattttg
    33721 agaggaggtt caccatgggt cgtagtttaa agaaaggacc ttttgtcgat gagcatttaa
    33781 tgaaaaaagt tgaagctcaa gcaggggttg aaaagaaaaa agttatcaaa acttggtcac
    33841 gccgttcaac agttttccca agttttgttg gatataccat cgcagtttat gatggacgta
    33901 aacatgtacc agtttacatc caagaagaca tggtaggaca caaattaggt gaatttgcac
    33961 ctacaagaac ttatcgtgga catgctgctg acgataagaa aacgaaacgc taatttgagg
    34021 ggaggataaa tccaaatggc agaacaaatc acatcagcta aagcaactgc aaaaacagtt
    34081 cgcacttcac ctcgaaaagc ccgtttagta attgacctta tcagaggtaa aagtgtcgca
    34141 gatgcaattt caatcttgaa attcacacca aacaaatctg ctggaatcat tgaaaaagta
    34201 ttgatgtcag cagttgcgaa tgcagaaaat aactttgact tagatgttga aaacttggta
    34261 gtaagcgaag cttttgttaa cgaaggacct acaatgaaac gtttccgtcc tcgtgcaaaa
    34321 ggatcagctt ctccaatcaa caaacgtaca agtcatatca cggtagtcgt atcagaaaaa
    34381 taaggaggga taatcagtgg gtcaaaaagt acatccaatt ggaatgcgtg taggcatcat
    34441 ccgcgactgg gatgctaaat ggtatgctga aaaagagtat gctgagttct tacacgaaga
    34501 tttaagaatc cgtaaattta tttcaactaa acttgctgat gctgctgtat caacagttga
    34561 aatcgaacgc gcaacaggtc gcgtaaacat ttcaattcac acagctaaac caggtatggt
    34621 tattggtaaa ggcggttctg aagtcgaaag cctaagaaaa gaattaaaca aattaactgg
    34681 taaaagaatc catatcaata tcgtggaaat caaaaaacca gatctagatg caaaattagt
    34741 aggtgaagga atcgcacgtc aattagaaaa ccgtgttgct ttccgtcgcg ctcaaaaaca
    34801 agccatccaa cgctcaatgc gtgctggcgc tcaagggatc aaaactcaag tatctggtcg
    34861 tctaaacgga gcagatatcg ctcgttcaga aggatactca gaaggaactg ttcctcttca
    34921 tactttacgt gcggacattg attacgcatg ggaagaagca gatacaacat acggaaaact
    34981 aggagttaaa gtgtggatct atcgtggaga aattcttcca actaaaaaaa acactgagaa
    35041 aggagggaaa taatcatgtt agtacctaaa cgtgtaaaac accgtcgtga attccgcgga
    35101 aaaatgcgcg gggaagctaa aggcggaaaa gaagtagcat tcggtgaata cggtttgcaa
    35161 gctgttgatt cacattggat cacaaaccgc caaatcgaag ctgctcgtat cgcaatgact
    35221 cgttacatga aacgtggtgg gaaagtatgg attaaaattt tccctcacaa atcttatact
    35281 gccaaagcaa ttggggtacg tatgggttct ggtaaagggg cacctgaagg atgggttgca
    35341 ccagtaaaac gtggtaaaat catgtttgaa atcgcaggcg ttcctgaaga agtagctcgt
    35401 gaagcgttac gtctagcttc tcacaaatta ccaatgaaaa ctaagatcgt aaaacgtgag
    35461 gaaatgggtg gtgaatcgaa tgaaggttaa agaaatcaga gaattaacca ctgccgaaat
    35521 gcttgatcaa gaaaaacaat taaaagaaga attgtttaat cttagattcc aattagcaac
    35581 aggtcaatta gaaaacactg cacgtattaa agaagtacgt aaatcgattg cacgcatcaa
    35641 aactgtgttg cgtgaacaag ctaagtaatt atggaaggag gccattaagc gtatgactga
    35701 aggaagaaat caacgcaaag tttatcaagg tcgcgtggtt tcagacaaaa tggataaaac
    35761 aattaccgtt gctgtcgaaa caaagaaaaa ccaccctatc tatggcaaac gcatgaacta
    35821 ttctaagaaa tacaaagtgc atgatgaaaa caacacagca aaagttggcg acatcgtgag
    35881 aattatggaa actcgtccat tatcagctac aaaacgtttc cgtttgttgg aagtagtcga
    35941 agaagcagtt attatctaat aacacgagat tttcctatat agattgaatg caaaatctga
    36001 aaggaggata cacaacgtga tccaagcaga aagtcgttta aaagtcgctg ataactcagg
    36061 cgcacgtgaa attttgacga tcaaagtcct tggtggatct ggtcgtaaaa ctgctaacat
    36121 cggtgatgtg atcgttgcta cggttaaaca agcaacgcca ggtggggttg tcaaaaaagg
    36181 tgacgtcgtt aaagccgtta tcgttcgaac aaaatcagga gctcgtcgta cagacggttc
    36241 atatattaaa tttgatgaaa atgctgcagt gattattcgt gatgataaaa gccctcgtgg
    36301 aacacgtatc tttgggccag ttgcacgtga actacgtgaa aacaacttca tgaagatcgt
    36361 ttcactagca ccagaagttt tataatcttg agacacttat caaaggaggt gcgaaacagt
    36421 tatgtttgtt aaaaaaggcg ataaagttaa agttatcact ggaaaagaca aaaacaaaga
    36481 aggcgttgta ctagcagcgt tcccgaaaaa agataaagtt attgtcgaag gtgtaaatgt
    36541 cgttaaaaaa caccaaaaac cttctcaagc tgctcctcaa ggtggaattg ttgagatgga
    36601 agcgccaatt catgtttcta acgtgatggt ggttgactct actggtgtag ctggccgagt
    36661 tggctacaaa gaagtagacg gcaaaaaagt ccgtgtttct aaaaaaaccg gtgaagtttt
    36721 agataaataa aagtttaagg aaggagggtc ttactgaatg aaccgcctaa aagaaaaata
    36781 tcttaaagaa gtaactccat cattgatgga aaaatttaac tatagctctg ttatgcaaac
    36841 acctaaagtt gaaaaaatcg tcatcaacat gggtgttggt gatgcggtat caaacgctaa
    36901 aaacttagat aaagcagttg aagaattaac tttgatcact ggtcaaaaac caatgattac
    36961 aaaagctaaa aaatcaatcg ctggattccg tttacgtgaa ggaatgccaa ttggtgcaaa
    37021 agttacattg cgcggagaaa gaatgtacga attcttagac aaattggttt ctgtttcact
    37081 accacgtgta cgtgacttcc atggtgtaag taaaaaagcc tttgacggtc gtggaaacta
    37141 tactttaggt attaaagaac aattgatctt cccagaagta gattatgatt tagtagataa
    37201 agtacgtggt atggacatcg ttattgtaac aacagcaaac tctgatgaag aatctcgtga
    37261 gttgttgaca caattaggca tgccattcca aaaataatta aaggaggcga actacgtggc
    37321 taaaaaatca atgattgcta aaaacaaacg tcctgcaaaa ttttcaacac aagcttatac
    37381 tcgttgcgaa cgttgcggac gtccacattc agtttatcgt aagttccatc tttgccgtat
    37441 ttgcttccgc gaacttgcct ataaaggtca aattcccggc gtgaagaaag ctagctggta
    37501 aaaagtaaat tcgcataaga aggaggtaaa agatcaatgg tcatgacaga tccaattgca
    37561 gattttctaa ctcgtatccg taacgcaaac atggttaaac atgagtcttt agaagtacct
    37621 gcatcaaaaa ttaaacgtga catcgctgaa atcttgaaac gtgaaggttt cgttcgtgat
    37681 gttgaataca tcgaagatga caaacaaggc gtgatccgtg ttttcctaaa atttggtaaa
    37741 aacggcgaac gtgttatcac aaacttaaaa cgtatctcta aaccaggttt gcgtgcttat
    37801 gtcaaagctg acgaagtacc aaaagtattg aacggtttag gtatcgcaat catttcgact
    37861 tctgaaggtg ttgtcactga taaagaagct cgtgaaaaaa atatcggcgg cgaagttatc
    37921 gcttacgtat ggtaatcaag tagaatctac aaggaggtgt ctttaagtga gccgtatcgg
    37981 aaataaagtc gttgttatcc ctgaaggagt aacagttact caagacggaa acaacgttac
    38041 agttaaagga ccaaaaggtg aattgactcg tactttttca gcagatatca aaatgaatat
    38101 cgaaggaaac gaagtaactt tcactcgtcc aaacgacagt aaagaaatga aaacaattca
    38161 tggaacaact cgtgcgaact tcaacaacat ggttgtaggt gtcagcgaag gtttccaaaa
    38221 agcgttagaa ctaatcgggg ttgggtaccg tgcacaatta caaggatcaa aacttgtatt
    38281 gaacgttggt tactcacatc cagtagaaat cacaccacca gctggagtaa ctgttgaagt
    38341 accagctaac acacaagtaa ttgttaaagg tgcgaacaaa gaagaagttg gcgaattagc
    38401 tgcaaacatt cgtggaactc gtcctccaga accttataaa ggtaaaggta ttcgttatgt
    38461 tggcgaatat gtacgccgta aagaaggtaa aactggtaaa taatcgttta gaaaaattgc
    38521 atagaagcca gcagcaggaa aaaggcattt ggctgaagtt taccttcaaa aaaatacatt
    38581 tttacttgtg ccgcagcttc tatttttcga aacgtattta ctgcttgaaa tagtagtaca
    38641 ataaaaataa agaggtgaca attgtgatta caaaaccaga taagaacaaa acacgtcaaa
    38701 agagacatcg tcgtgtacgt aacaatatct ctggtactgc tgagcgccca cgcttgaacg
    38761 tttttcgttc taacaaaaac atctacgctc aaattattga tgacgtagcg ggtgtaacgc
    38821 tagcaagtgc ctctaccttg gataaagaaa tttcaggtgg aacaaaaaca gaagcagcac
    38881 aagctgtcgg taaactagtt gctgaacgtg cagctgaaaa aggcattaaa gtagtagtct
    38941 ttgaccgtgg tggatacctt taccatggcc gtgtgcaagc tttagctgaa gctgctcgcg
    39001 aaaatggact agaattttag aagaaggagg aataccattc atggtttata tcgatccaaa
    39061 acatttggaa ttagaagacc gcgttgttgc aattaaccgt gtaacaaaag ttgttaaagg
    39121 tggacgtcgt ctacgttttg ctgctttagt tgttgtcggt gacaaaaacg gacacgtagg
    39181 gtttggtaca ggtaaagctc aagaagttcc tgaagcaatc cgtaaagcaa ttgaagatgc
    39241 gaagaaaaac ttagttgaag tacctatggt tggttcaaca atcccacacg aagtaatcgg
    39301 tgcttttagt ggtggtagaa tcctaatgaa acctgctgta gaaggttctg gggttgctgc
    39361 tggtggacca gttcgtgccg tattagaatt agctggggta gcagatatca cttctaaatc
    39421 tttaggctca aatacaccaa tcaacgttgt tcgcgcaaca gttgaaggtt tgaaacaatt
    39481 gaaacgtgca gaagaagttg cagaacttcg cggcaaatca gttgaagaat taatcggata
    39541 aggaggacaa caataatggc tgaattaaaa gttactttaa aacgcagtat tatcggacgt
    39601 cctcaaaacc aacgcgatac agttaaagcg ttaggtctta caaagattaa cagttcagtg
    39661 gttaagcctt ctaatgaagc aattaaaggc atgatcaata ctgtttctca cctagtggac
    39721 gttgaagaaa tttaatttag aaaaatcata actagaacat taaggaggtg ccaaacctat
    39781 gaaacttcat gaattaaaac ctgctgaagg ttcacgccaa gtacgtaacc gtgttggtcg
    39841 tggtacttca tctggtaacg gaaaaactgc cggacgcgga caaaaaggac aaaaagctcg
    39901 ttcaggcggc ggtgtgcgtt taggatttga agggggacaa acaccattgt tccgtcgttt
    39961 accaaaacga ggattcacaa acgtgaaccg taaagactat gcagtcatta atcttgatgt
    40021 attgaaccgc tttgaagacg gagctgaagt aactcctgtt gctttagttg aagctggaat
    40081 cgtgaaaaac gaaaaagctg gaatcaaagt attagctaat ggggaactaa acaagaaatt
    40141 aactgtgaaa gcagcaaaat tctctaaagc agctcaagaa gcaattgaag cggctggtgg
    40201 atcaatcgag gtgatctaat gtttagacta ttaaaagatg cttttaaagt aaaagacatt
    40261 agatcgaaaa tcctatttac tgtatttgtg ttgtttgtat ttcgcctagg tgcacatatt
    40321 actgtaccag gcgtaaatgc tgcttcattg caaaaccttt cttctttgcc atttttcaac
    40381 atgttgaact tggtaagtgg tagtgcgatg caaaactttt ccattttctc aatgggggtt
    40441 tcaccataca ttactgcttc tatcgtcatt cagcttcttc aaatggacat cgtgcctcga
    40501 tttgttgaat ggtcgaaaca aggggaagtt ggtcgtaaaa aactgaatca agcgactcga
    40561 tatctgacat tagtattggc atttatccaa tctgtcggta tcactgctgg attcaatcaa
    40621 tacgctcaat taggtttcgt gaataatcct aacgtagcaa cttacgtaac gatcggtttg
    40681 attctaacag ccggtacgat gtttgttact tggctaggag aacagatcac agaaaaaggt
    40741 atcggaaatg gcgtatcaat gatcattttt gcaggtatca tttctagatt gcctgaaagt
    40801 atcagagaaa tttatgaaga ttactttata aatattgatc cttcagacat atggaaatct
    40861 gctatttttg tggccatttt actagtagcg gtcttgttga tcgtgacatt cgtaacattt
    40921 ttccaacaag ctgaacgcaa gatcccgatc caatatacga aacgcgtagc tggcgcgcct
    40981 acaagcagct atctgccgtt gaaagtaaat gcagctggag ttattccagt tatctttgct
    41041 agttcgttta ttgctacgcc aaatgctgtt ttacaagcat tgagcggtag attcggttct
    41101 gaaaactggt acaaagtgat gatggagatc tttaactata atacagcacc tggtgctacg
    41161 atttatacga ttctgatcgt tgccttcact ttcttctacg cctttgttca agtaaaccct
    41221 gagaaattag cggaaaactt gcaaaagcaa ggaagttata taccaagcgt acgccctggt
    41281 aaggggactg aagagtatgt ctcaagatta ctgatgcgtt taagtacagt tggtgcagtc
    41341 ttccttggtt tagtggcatt gcttccaatc attgctcaaa tggtttggga tcttccacaa
    41401 tcaatcggat taggcggtac aagcttactg atcgttatcg gtgtagcttt agaaactgcg
    41461 aaacagttag aaggcttaat gctgaaacgt aaatatgttg gattcattga gtaagaaagc
    41521 gtgttgaggt ttcccctcaa cacacgttct cacacattta ttaggaggga aaacaatgaa
    41581 cctcatttta atggggctgc caggcgcagg taaaggaaca caagctgaaa aaatcattga
    41641 tgcttatggt attccgcaca tctcaacagg agatatgttc cgcgcagcga tgcaaaacga
    41701 aacagctctt ggcctggaag caaagtctta tatggataaa ggtgcattag ttcctgatga
    41761 agtaacaaat ggaatcgtga aagagcgact agctgaacca gatacagaga aaggcttctt
    41821 attagatggc tttccacgta cgctagatca agcaaaagct ctggacgcaa tgctaaaaga
    41881 tttgaataaa aaaattgatg ctgtcatcga tatccatgtt ggtgaagaaa tcttggtcga
    41941 acgtctagcc ggccgattta tctgcagcaa ttgtggagca acttaccata aaattttcaa
    42001 ccctacaaaa gttgaagaca catgtgatcg ttgcggtggg catgaattct atcaaagaga
    42061 agatgataaa cctgagacgg ttaaaaatcg tctggctatc aacatcaaaa atagtgaacc
    42121 aatcttggct tattataaag aacaaggttt gctaaacact attgatggtg ctcgtgaaat
    42181 cgatgctgta tttgcagatg tacaaaaaat cattgaaaaa tagcacgatt gcccgtagcc
    42241 gacttgcatt atgcagttac tcttgtcaag ttcaataaat tatgatagaa tatgtcagtc
    42301 cgacttctag agaatcctct agatgatcca ttttgagaat tttgaggtgg gaactgcagt
    42361 ttccgccatt ttatcgtgtg aaaatgcgaa acaagtacaa ggaggtactg tgcgtggcaa
    42421 aagaagatat gattgaagtc gaaggtacag tcgtcgaaac tttgccgaat gcaatgttta
    42481 aagttgaact agaaaacgga caccaagttc ttgctactgt ttcaggtaaa attcgtatgc
    42541 attacatccg tatcttacct ggtgacaaag taacggttga attgtctcca tacgatctta
    42601 accgtggccg tattacttat cgctttaaat aattgtactc cgtaaaacta caggaggtat
    42661 tatcatgaaa gtaagaccat cagtaaaacc aatgtgcgaa cattgtaaag taattcgtcg
    42721 taaaggacgc gttatggtga tttgcccagc aaatccaaaa cataaacaac gtcaaggata
    42781 attggaggtg ctataaatat ggctcgtatt gcaggagtag atattcctcg tgataaacgt
    42841 gtagtagttt cacttactta tatctatggt attggtaaca ctactgctaa aaagatctta
    42901 gctgatgctg gtgtatctga agatgttcgc gttcgtgaat taacgaatga acaaacagat
    42961 gctatccgtg cagaagtaga taaattaaaa gttgaagggg atcttcgtcg tgaagtgaac
    43021 ttgaacatca aacgtttgat ggaaatcggt tcttaccgtg gaatccgtca tcgccgtgga
    43081 ttgcctgttc gtggacaaaa cacgaaaaac aatgcacgta ctcgtaaagg cccagctcgc
    43141 gctatcgctg gcaagaaaaa ataattctta agtgaaggag gttaaaactt catggcagca
    43201 aaaaaagtga atcgtaaacg ccgtgtgaag aagaatatag aagcaggtat tgcacatatc
    43261 cattctacat tcaataacac tatcatcatg atcactgata ctcacggaaa tgcattagcg
    43321 tggtcatcag ctggttcatt aggtttcaaa ggaagcaaaa aatcaactcc ttttgccgct
    43381 caaatggcag cagaaactgc tacaaaagca gcaatggaac acggattaaa gactgttgaa
    43441 gtaacagtta aaggacctgg ttctggacgt gaagcagcaa ttcgttcatt acaagctaca
    43501 ggtttagaag tgactgcaat tcgtgacgtg actccagttc ctcataatgg tgcccgccct
    43561 ccaaaacgcc gtcgtgttta atgagtgccg ctcattttga gttttatcag taacgtcatt
    43621 gaacaagaca cttttcgttt tgaaaggggt aaagataaga atgattgagt tcgaaaaacc
    43681 aagaatcgca aaaattgatg aagaaaaaga ttatggcaag ttcatcgttg aacctcttga
    43741 aagagggtat gggactactt tagggaattc cctacgtcgt attttattat cttctttgcc
    43801 aggtgctgcc atcactaata ttcaaatcga tggtgtactg catgaattct ctaccatcaa
    43861 aggtgttaga gaagacgtca ctcaaatcat cttgaacatt aaaggcttag cgctgaaaat
    43921 gtatggccaa gaagaaaaaa cccttgaaat cgatattacc ggacctgcta cagtaactgc
    43981 tggcgatatt atcgttgata gtgatgtaga aattcttaac aaagatatgt acatctgtag
    44041 tgtctctgaa ggagctacgt tccatgctcg cttaacagtg aaacctggac gtggttatgt
    44101 tcaagcagat gaaaataaaa aagaagatat gccaattggc gttcttccag tcgattcaat
    44161 ctacacacct gttcgtcgtg tgaactatca agttgagaac acacgtgttg gacaccgtga
    44221 agattttgat aaattgacga tggagatttg gacagatggt tcaattgaac cgttggaagc
    44281 aatgagtttg tctgcgaaaa tcatgactga acatttggat atttttgtga acttaactga
    44341 tgaagcaaaa aatgctgaaa tcatggtcga aaaagaagaa acacaaaaag aaaaaatgtt
    44401 ggaaatgacg atcgaagagt tagacttgtc tgttcgctct tacaattgtt tgaaacgtgc
    44461 aggaatcaat actgtacaag aacttacaaa taaatctgag cctgaaatga tcaaagtccg
    44521 taacttagga cgtaaatcat tagaagaagt taaagcaaaa ttgcacgact taggtttagg
    44581 tttacgtaaa gaagattaaa accttttacg aaggagggaa accaacgtga gttatcgtaa
    44641 actaggacgc acatctagcc aacgtaaagc gatgttgcgt gatttaacaa ctgatttatt
    44701 aatcaacgaa cgtattgtga ctactgaagc tcgtgcgaaa gaagttcgct caactgcaga
    44761 aaaaatgatc actttaggta aacgcggaga tttgcatgca cgtcgtcaag ctgcggcttt
    44821 cgtacgtaat gaagttgcca gcgtgcgtga agaaaatgag gacatcgtca ttgaatcagc
    44881 tttacaaaaa ctgttcaacg atattgcacc tcgttacgca gaacgtcaag gcggatacac
    44941 acgcattttg aagacagaac caagacgcgg tgatggtgca ccaatggttg tcttagaact
    45001 tgtctaaaat cacactaata acatcacttt atagatgatt cttttagagt gttatgatgt
    45061 tggaagatat ttttccgagt ctagctcagc gctgctcctc aagcgaatat cgcttgggga
    45121 gtaagcactc atcataaagt gtttttttat accttcaatt acctgtcatg acagatatgt
    45181 ttgaaggcat aaaaaaacat tttaagcgag aaataattga aaattttgtc tttttttgat
    45241 agtgttagta ggaactttag gatgaagaag gagtaatcat ggagccaatt attgaattag
    45301 aaaagataaa ttataaatac cagccagatg atcttcgccc cgcattgaaa gatgtctcct
    45361 ttacaattga taaaggtgag tggatcgcta ttattggaca caatggttca ggaaaatcga
    45421 cacttgccaa aacgatcaat ggattgcttc tgccagaatc agggatcgtg aaagtgggaa
    45481 atcaaatatt ggatgaagaa aatatttgga cgatccgaca gatggttgga atggtttttc
    45541 aaaatccaga caatcagttt gttggttcga cagtagaaga tgacgttgct tttggtcttg
    45601 aaaatcaagg gattcccaga gaagaaatgc tagtgcgtgt gaaagatgca cttgagaaag
    45661 ttagaatggc tgagtttgct tcacgcgagc ctgctcgttt atcaggaggg caaaaacaac
    45721 gtgttgccat tgccggcgtg gttgccttac gacctgatat cattatttta gatgaagcaa
    45781 ccagtatgct agatccagaa ggtcgtgaag aagtgatctc tacgatcaag aagatcaaag
    45841 aagaaagtca attgaccgtt atatctatca ctcatgatat tgatgaagca gctaatgcca
    45901 atcggatact agtgatgaga caaggcgaac ttgtccgtga aggtacacca aaagaaattt
    45961 tttctgctgg tcctgaactg atcgacttag gtctagatct accatttcct gaaaaactga
    46021 agagcgcact gaaagaacgt ggggttgatg tgcccagtga atatatgaca gaagaaagga
    46081 tggtggattg gttatggaca tccgttttga acaagtagac ttcacttatc agccgaatac
    46141 accatttgaa caaagagcct tatttgacat caatatgacg atcaaagaaa acagttatac
    46201 tgcattagta gggcataccg gaagcgggaa atcaacctta cttcagcatt tgaatgcgct
    46261 tgttaagcca acaagcggta cagtccatat tggagaacga gatattcagc cggatacgga
    46321 taataagaat ttaaagccca tccgaaaaaa agttggcatc gtctttcagt ttccagaagc
    46381 acagctattc gaagaaacgg tagcaaaaga cattgctttc ggtcctaaaa actttggtgt
    46441 cagcgaagaa gaagcactag tcctagcaaa agaaacatta gaacaagttg ggctggatga
    46501 aagctatttg gaacgttcgc catttgaact ttcaggaggg caaatgcgta gagtagcaat
    46561 cgctggtgtg cttgccatga ggccggaagt acttgtattg gatgaaccaa cggcaggact
    46621 tgatccccag ggtagaaaag aaatgatgga gatgttttgg cgtcttcata aggaacagca
    46681 gatcactatt gtattagtta cgcatttaat ggatgatgta gccaattttg cagattatgt
    46741 ctatgtgttg gaaaagggac gaatcgttaa tagcggggag ccgcaagagg tctttcaaaa
    46801 cattgaatgg ctaaaagaaa aacaactagg cgtacctact gccaccgagt ttgcagaaga
    46861 attaatggct aaagggatga actttgctac cttgcctttg acagctgaag aattagcaga
    46921 cgctatcgtc cattatgctg gaggaaatgc ccatgatgaa taaattgata tttggtcgtt
    46981 atatgcctgg agattccttg atccatcgat tggatccccg agctaaatta ttagccagtt
    47041 tttattttat cggaatcatt tttttagcaa ataattggga aacgtacctt ttgttggcat
    47101 ttttcacatt actttctgtc ttcttgtcaa aagtagattt gaaatttttt atccgaggca
    47161 ttcgcccatt gatctggcta atcctcttca ctgtagcttt gcaggtcttg tttacaagtg
    47221 gcggagaaac ttattggagt tggggtgttt tccatatcac tgaatttggt gtgatgaacg
    47281 gcctctttat tttctgtcga ttcgtgttga tcatttttat gtcgactcta ctcacgctta
    47341 ctacaccgcc tttggaatta tcggatgcga ttgagtactt gcttcgtcca ttgaaagccg
    47401 tacggttccc agtccacgaa atttcattga tgctgtcgat tgctcttcgt tttgtgccta
    47461 cattgatgga cgaaacagaa aagatcatga acgctcagcg cgctcgcggt gttgattttg
    47521 gtgaaggaaa cctagttcag aaaatgaaag cagtcattcc tttgctgatt cctttatttg
    47581 tcagcagctt caaccgtgcg gaagatcttg cgactgctat ggaagcaaga ggctacaaag
    47641 gtggggaagg aagaacgaaa tatcgtgtat tgcattggca taatagagac acgatggtta
    47701 tcattgcttt tgtattatta actgtgctac tgatcttttt gagaggataa acgttcagtg
    47761 ggccgctatc tattcttttc ttgctgatct gtttgcaaga aaggatgcga gcagtgtatg
    47821 acaagaaata ttagggtctg tggcagacta aggtcacagg cctctttctt ttatctgaaa
    47881 agaaagaacg aaaaaatttt ataaaaaaat cattattcca gataaccttt taggaacaaa
    47941 ggagagaaaa acatggtacg ttacaaagca atcattgcat acgacggaac aaattttaat
    48001 ggattccaaa aacagccaaa tgggcgtact gttcaagaag aagtagaaaa aacattacaa
    48061 aaaatggcaa atggaaaaga aatcacggtc tttggttcgg gaaggacaga tgccggagta
    48121 catgcgattg ggcaagtaat ccattttgat tatccagagg agcgtccgtt agaacgaatg
    48181 cgtttcgcgc tagataccca gtcaccagag gatattgctg taagacaagt agaaattgtt
    48241 tcagaagact tccacgcaag atatttggtc aaagaaaaga cgtatcaatt tcgagtggat
    48301 atagggaaac cacgcagtcc ttttcgacgc cattatgcaa gttattttcc ttaccctctt
    48361 gatttggaaa aaattcagcg ggcgcttcct gatttattag ggactcacga tttcacctct
    48421 ttttgtgcat caggaagctc gatagaggat aaagtacgta cgatctacga ggctaagatg
    48481 gaggtaaatg aaacaaaaga cgaattgttg tttacattta ggggaaatgg cttcttgtat
    48541 aagatgatac ggatcttagt aggaacgctt ttgaaaattg gcaatggccg attgcctgaa
    48601 gatagtatcc cagatattat tgcgaaaaaa gatcgtaatg cagcaggacc tacagcacat
    48661 cctgaaggac tttatttgta tgaagtgaaa tatgaataag aggttgtgac agaagtggtc
    48721 agcttcaaga aataagaagg aatttacgaa aattacttct caaaattttg caaaatttcg
    48781 gcttattttc gaaggagcta cttctggaac accgtgaatc agaggttgtg aaaaagctgc
    48841 cctgcatcaa gtaataagaa caaccaaaca aaaatagctc gtcatatttt tcgtttggtt
    48901 gggcttatta ccgcagatgc aagcttttga acaccgttta aggaagaggt tgtgaaatca
    48961 gcgttttgac ctgagtatta gagaaacaaa cggaaaaata gttcctcata ttttgccgtt
    49021 tgttgagcta ataccgaagg tcagctgatt gaacaccgtt taagaaagag gtcgtgagcc
    49081 tgtcatttaa ctctgagtca caagtaacaa tttcaaaaaa cagcttctca tctttgatga
    49141 atatcgtgac ttgtggacga ggcgttgata agtgaatcat ctttttgtta cctatttttt
    49201 ctgtaaccaa aaaacgatgg aacgttgttt tgattgccct taatgaggac agtcggaaca
    49261 ggtttgtcat ttttatattt aaatggcaca aatttttcta attatttgtc atttagcgct
    49321 gaaaattttt gctatttatc taaaaaagtg ataactactt aagatgaagc agaatattta
    49381 cgccatacgg catacaaccg cgaaaaatat aaaaaaaaga aaacgattga acgcgttttt
    49441 gcagtcgcaa aggaaaagca tggaatgcgc tacatcaagt atcgagactt ggaaaacaat
    49501 caggtgtata cgctgattgt ttttgctgca atgaatctga aaaagttgtc cacttggcag
    49561 ttggaacata tgtcttcata tcttttatta tacaaaaata gcaaaagcac cagtctacac
    49621 tcttagtaaa gaggaaactg atccttttgt ctacattctt aaagtactta aactaagtac
    49681 tttattttac tctttaggat tgatacagta gcatctatcc ctttattaat aatcttttat
    49741 ttttttaaat aaagatgttg tctccatctt caggcactaa aactttttcg gaaattcctt
    49801 tttctttatt gaaagacttt aattcttctc ttgacagtcc ccaatggttt acagcttcca
    49861 tatgaacggc aataattgtg gaatctggta ttgctttatg caattcatat aaatcgtctt
    49921 tccccataat aagagattct ccaactaaaa aatgattatc tccagcattt gctactatga
    49981 tttctggatt atactgatca atagtttgtt taacagcttc ataccaaact gtatctcctg
    50041 taaagtatag tgtcttctca gtcgaatgtt tgaaaacaat accgcaaaca ttacctacat
    50101 aattcaagat ttctcctctg ccatgtttgc cttttgtttt aaccaattgt atagattcaa
    50161 aaactgtgtc ttctcgtagt acctccacat ttttaaaacc atatagtcga atttcattcg
    50221 catcattttc atcttgcaca aataatttta tttctttagg taggacctct ttcgctatat
    50281 cgtcccaatg atctagatgt aaatgtgtta caataacagc atcaataccg ttgataatat
    50341 cttcgactgg cattggcaaa tcaactagag gattcatttg atcttttctt ggtgatggaa
    50401 aaggaccttt cgaaataaat ggtggaagtg ttcctttttc cgctaacatt ggatcaatta
    50461 aaaatttttt acctccatag tctaagatag ctgttgcatt acgaatgtga tgtatattca
    50521 taaacgttgt ctcctttttg ttgatatgaa atatttttag tataattcaa ttccatacaa
    50581 taaataaacc gaacaaaaaa agtcttttac tatttttact taatttatga aaggttgttt
    50641 accatgttag accaaacaga tataaatatc attgaggaac tatcaaaaaa tagtcgaatc
    50701 acaatgaaag aacttggaga aaaagtacat ttgactggac ccgctgtctc ggcgagagtg
    50761 acaaaactag aggaaagtgg agttattgaa aattatacag taaaattaaa tatggaaaag
    50821 ctagggtttt cgattcacgc ttttttaatt ataattacg
//
LOCUS       DAZKKZ010000016        46239 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.016, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000016 DAZKKZ010000000
VERSION     DAZKKZ010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 46239)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46239)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46239
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.016"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(50..2125)
                     /gene="glyS"
                     /locus_tag="ACG8LA_000976"
     CDS             complement(50..2125)
                     /gene="glyS"
                     /locus_tag="ACG8LA_000976"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004820 - glycine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006426 - glycyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HFQ0203291.1"
                     /translation="MAKDLLLEIGLEEMPAHVVTPSMKQLEEKTAKFLDENQLTYDTI
                     ETFSTPRRLAIKVTNIPERQADSEEEVKGPAKKIALDADGNWTKAAEGFVRGQGLTTD
                     AITFRELKGVEYVYVTKYTHGKESKEVLTGLADVIKSLTFPVTMHWAEYDFEYIRPIH
                     WIVALLDDEVIPFEILDVKTGRASRGHRFLGEDVTFAHAKEYEEKLNEQFVIASPQKR
                     QEMIVTQANELAEKNHWVIDLDEDLLEEVNNLVEYPTVFSGDFEEKYLSVPEEVLVTS
                     MKEHQRYFEVRNDQGMLLPHFISARNGDRVKLENVVRGNQKVLTARLEDAEFFYNEDK
                     KASIDQYVEKLKTVTFHEKIGSIYEKMQRVQVIARIIGEQVGLSEEELMDLQRAAEIY
                     KFDLVTNMVGEFPELQGIMGEKYALLKGEKPAVATAIREHYMPISSEGELPQSTVGSV
                     LAIADKLDSIFSFFAVGMIPSGSNDPYALRRQAYGVVRIIESKKWAFPLSVLQETISD
                     VISKDTDRFGIGLSEGQQQVIDFIKGRLRQLLTTKNIRHDVIDAVLNAEQKDLTKVFA
                     AAQLFKQHLADEDFKPSMEALTRVVNLAKKAQLEKQSEVDPELFENDAEKELHKAVEA
                     MKASFADQTIHENYDQLVALRPLIENYFDQTMVMADEPAVRKNRLTQLSQIAAMALSL
                     ASLDQIITK"
     gene            complement(2127..3044)
                     /gene="glyQ"
                     /locus_tag="ACG8LA_000977"
     CDS             complement(2127..3044)
                     /gene="glyQ"
                     /locus_tag="ACG8LA_000977"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004820 - glycine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006426 - glycyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HFQ0203292.1"
                     /translation="MSKKLTVQDMILTLQKFWSSNGCMLMQAYDTEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPENIQELYLESLRL
                     LGIDPLEHDIRFVEDNWENPSMGCAGVGWEVWLDGMEITQFTYFQQVGGLPCKPVTSE
                     ITYGLERLASYIQEVESVYDLEWADGVKYGEIFKQPEYEHSKYSFEVSDQDLLLSNFD
                     RFEKEAKRCIDENLVHPAYDYILKCSHTFNLLDARGAVSVTERAGYLSRIRNMARAVA
                     KIFVAEREKLGFPLLNKNTANPENVKEAE"
     gene            complement(3430..4242)
                     /gene="recO"
                     /locus_tag="ACG8LA_000978"
     CDS             complement(3430..4242)
                     /gene="recO"
                     /locus_tag="ACG8LA_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HFQ0203293.1"
                     /translation="MSQLAESKGLILSSRNYKEKDKLVKIFTESSGKMMFYIKGIHRQ
                     NQPLAPALLPFTEAVYIGNFRSEGLSFLSSVKDVHAFRHIQEDIFLSGYGTYLLNLVD
                     AAIEDHQYDPHLFQFTQQALQRMDQGDDAEIITNIFEVQILQRFGIAPIWTHCVVCGE
                     TKGKFDYSSKYGGVICERHWSMDDHRYHADPRAVYFVRMFSAISYDKISGIHLKEETK
                     QAIRELIDQLYDEYVGIHLKSKKFIDQMKSWAHVLKTSEKDMSEKDLPKKEE"
     gene            complement(4385..5284)
                     /gene="era"
                     /locus_tag="ACG8LA_000979"
     CDS             complement(4385..5284)
                     /gene="era"
                     /locus_tag="ACG8LA_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HFQ0203294.1"
                     /translation="MPEHKSGFVAIVGRPNVGKSTLLNRIVGQKIAIMSDKAQTTRNK
                     IQGVYTTPEAQLIFIDTPGIHKPKHRLGDFMVEAAYSALKEVDAVLFMISADQKRGRG
                     DDFIIERLKNVHSPVYLIINKIDKIHPDELLGIIEDYSTQMPFAQVIPISATEGNNVE
                     RLMDVLVSEMPEGPQYFPDDQVTDHPEYFIVSELIREKVLFLTRDEVPHSVAVVVDSM
                     KRNENDKIHIQATIIVERDSQKGIIIGKGGKMLKQVGTKARKDIENLLGDKVFLELWV
                     KVQKDWRDKKVYLQDFGYRKDEY"
     gene            complement(5299..5694)
                     /locus_tag="ACG8LA_000980"
     CDS             complement(5299..5694)
                     /locus_tag="ACG8LA_000980"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016301 - kinase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HFQ0203295.1"
                     /translation="MDLKDKNVEKNKHFLMSVEFAVQGVKTVFEEERNMRKHVAFGIL
                     ALFMGVIFQLDRIEWLWLLLAVFLVWIVEIINTVFENVVDMFTDFHFHPIGKKIKDMA
                     AGAVLVTACFSVIVGLILFVPKIYHLLFN"
     gene            complement(5678..6154)
                     /gene="ybeY"
                     /locus_tag="ACG8LA_000981"
     CDS             complement(5678..6154)
                     /gene="ybeY"
                     /locus_tag="ACG8LA_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HFQ0203296.1"
                     /translation="MDITFMDETNQVSEEKMKEIDDLLQFAASYLELPEETEMSVTFM
                     DNAAIQVINRDYRGKDAPTDVISFALEEEGEDEIPVIFEDGENPLPRVLGDIMISTER
                     AAEQAEAYGHSYDRELGFLAVHGFLHINGYDHMTPEDEKEMFGLQKEILDAYGLKR"
     gene            complement(6171..8363)
                     /locus_tag="ACG8LA_000982"
     CDS             complement(6171..8363)
                     /locus_tag="ACG8LA_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDIG domain-containing metalloprotein"
                     /protein_id="HFQ0203297.1"
                     /translation="MLNKTLQKLQEKLGKAALPFLLFLFFIIVCGVTFSSVKQKANDF
                     REGQVAEESIRANKTIENTEETEQRRKLAAEAVTPEYTYQKDLADDQNNRIKQLFELI
                     DKTNDTINKSYNDKVDKAKEDENIPKPTTEERIATLKKNFENVNAENVAFYQKLPNNF
                     YSTIFEMTETEIHTVRDESLKLIDEQMSKQVRESELEAFKQEAEDQIQYLNVTTEQQQ
                     MIRYLVDQGIVVNDVLNEKKTEELKQSAREAVQPVMIFQGEIIVREGNQIDASAMKKL
                     ELLGLTNQTTSIFPLIAMVLAVLLQIGVLIYNSLQFQNAGERTKYVLFYVTAMSVSVV
                     LMKFFQLFQTEQAAYIPLFYPAAFAPLVLSFFLNRRAGIMAGIFQAVSALFIFYDSIG
                     TNFLTVILMSYVFSGLMATIVRRKRISEQGLSAAMWVIIFPVMMDVILIIYQGMSFGD
                     ATTWLTLVCGFTGALFSFLLTIGLHPYIELMVNDDSVIVLNELSNPNHPLLKQLLEEA
                     PGTYHHSMMVANLSANAVAEIGGRSLLTRVACYYHDIGKIKHASFFVENLPSGAENPH
                     NFLLPEDSKHIIFGHVTDGAKILEDYNMPQMVIDICRQHHGTTLMRYFYVKAKERNPE
                     VTEEQFRYPGPKPQSREAGIVNIADSCEAAVRAMDHPTSEKIESFVHNLIEERISDGQ
                     LDDSGLTLKEIRKVEKSLISGLSSTFHSRIKYPKMKSEVEKIKEEQEE"
     gene            complement(8387..9358)
                     /locus_tag="ACG8LA_000983"
     CDS             complement(8387..9358)
                     /locus_tag="ACG8LA_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HFQ0203298.1"
                     /translation="MTEESSSLEIRLTAADDVSMLLGAHDKHIKLIEETTETTIHTRG
                     EIIQIIGEQSQISLAASVIRTLQELIKRGIHVSTPDVVTALKMGQKGTLDYFVEMYEE
                     EIVKDRNGKPIRVKNSGQKKYVESVAKHDIVFGVGPAGTGKTFLAVVLAIAALKKGEV
                     QKIILTRPAVEAGENLGFLPGDLKEKVDPYLRPVYDALYQIFGLDHTNRLMERGVIEI
                     APLAYMRGRTLDDAFVILDEAQNTTVAQMKMFLTRLGYQSKMIVNGDTSQIDLPRGTT
                     SGLVHAERTLKQIKKIDFVNFEASDVVRHPVVAEIIKAYEKADLHQE"
     gene            10064..11443
                     /gene="brnQ"
                     /locus_tag="ACG8LA_000984"
     CDS             10064..11443
                     /gene="brnQ"
                     /locus_tag="ACG8LA_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015658 - branched-chain amino acid
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015803 - branched-chain amino acid
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HFQ0203299.1"
                     /translation="MEETKTYSWKQLLMVSSLIFGMFFGSGNLIFPVHLGQMAGANWV
                     SAGVGFAISGALFPLLAILAVVVTKSDGLYDLAKPVGKWYAALFLILVHLTIGPFFGT
                     PRTAATAFEMAAKPFLPEKYNSLGMFLFSALFFLLAYFLTVHPTRLVKYVGKYLNSLF
                     LALLAIIFVVSLFHPMGNLNQSAADTYQTNALTNGVLEGYNTVDAVALLALSVTFVHA
                     VRDLGFKDKKVTELTAKAGSLSVALEVMIYFGLVLLGAMSLNKMSLSENGGTALSQIT
                     NFYLGNFGASFLGVMVTLGVFTTAMGLVVSFAQDFHKLFPKVSYMTWLRLTTFVSFVV
                     ANAGLDNIIQWSLPVLMLLYPLSLALILLSLTAKFFQKTPFVYQVTMLFAAVPAVLDM
                     LANSPALVSQQRVVASMLEFYHHHVPFAALGLGWMVPTLLGYAGSLLFYYAYRLSGYK
                     QEANELPEE"
     gene            complement(11599..12045)
                     /locus_tag="ACG8LA_000985"
     CDS             complement(11599..12045)
                     /locus_tag="ACG8LA_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GatB/YqeY domain-containing protein"
                     /protein_id="HFQ0203300.1"
                     /translation="MSLLSRLNDDMKTAMKAKDKESLQVIRMIKSSIQNEQIKEGHDL
                     TEEEELTVLSREMKQRRDSLHEFEEAGRDDLAEKVKSEIVIVEKYMPEQLSDEEIRQL
                     VQEAITQTGASSMKEFGKVMGAIMPKVKGKADGNQVNAIVKELLQS"
     gene            complement(12072..12248)
                     /gene="rpsU"
                     /locus_tag="ACG8LA_000986"
     CDS             complement(12072..12248)
                     /gene="rpsU"
                     /locus_tag="ACG8LA_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HFQ0203301.1"
                     /translation="MSKTVVRKNESLDDALRRFKRSVSKAGTLQESRKREFYEKPSVR
                     RKKKSEAARKRKKF"
     gene            complement(12410..12838)
                     /locus_tag="ACG8LA_000987"
     CDS             complement(12410..12838)
                     /locus_tag="ACG8LA_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fur family transcriptional regulator"
                     /protein_id="HFQ0203302.1"
                     /translation="MKKQTLIEQSLETLKNNGFKYTKKREALLTYLVKRNRYVSAKEV
                     FDYMNQEFKGVSYDTIYRNLHDFAEIDLLEETDLNGEMKFRFHCCQGEIGHHHHFICT
                     VCGTTKEIHMCPMNYFEEQLGGCTIEGHRFEIFGRCENCQ"
     gene            12930..13790
                     /locus_tag="ACG8LA_000988"
     CDS             12930..13790
                     /locus_tag="ACG8LA_000988"
                     /EC_number="2.7.11.33"
                     /EC_number="2.7.4.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004674 - protein serine/threonine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016776 - phosphotransferase activity,
                     phosphate group as acceptor [Evidence IEA];
                     GO_process: GO:0006468 - protein phosphorylation [Evidence
                     IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate, water dikinase regulatory protein"
                     /protein_id="HFQ0203303.1"
                     /translation="MSSDSTEIVTFFVISDSAGETATKLAQATMAQYPTVEFNLFRRT
                     FVTDEKTLMQALQDALKEKALVLHTLINQELIEMTRSFCEEHQLFSFDVMTPPISEIE
                     RLTGIKPIRQPGALHLLNENYFKRIKAMEFAVKYDDGKDPRGFLEADVVLLGVSRTSK
                     TPLSLFLANKNLKVANLPLIPQAHIPKQLWEIDPKKIVGLTNNPDILNNIRKERMRSY
                     GLNPDTAYSDIEKIRAELDFANDLYEKLGCVVINVASLSIEETASLILNALDLEDHSY
                     YGTETTEETD"
     gene            complement(13884..14234)
                     /locus_tag="ACG8LA_000989"
     CDS             complement(13884..14234)
                     /locus_tag="ACG8LA_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="HFQ0203304.1"
                     /translation="MEKVVNFRSQSFFKLEVNGLPDTQKTKVEKVSQLFKMLSDPTRL
                     KILLYLKDGEQNVTAITQAVEMEQSAVSHQLRLLRENHVVKSHREGKAILYSLDDSHV
                     LDILNQTLKHVEHQ"
     gene            complement(14250..15977)
                     /locus_tag="ACG8LA_000990"
     CDS             complement(14250..15977)
                     /locus_tag="ACG8LA_000990"
                     /EC_number="5.4.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016868 - intramolecular
                     phosphotransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HFQ0203305.1"
                     /translation="MSWEQVYEQWVHEENLEENLKKQLIDLGEDPEKLEDAFYAPLEF
                     GTAGMRGILGPGINRMNIYTVRQATEGLARFMDTQGEETKRRGVAIAYDSRHQSPEFA
                     MEAAKTLAHHNIPSYVFESLRPTPELSFAVRHLKTFAGIMVTASHNPAAYNGYKVYGE
                     DGGQMPPADADALTKYVREVSNPLKVEVLSDDEAEHSGLITIIGEEVDAAYLEEIKAV
                     TIDHELVETMGKDLKLVYTPLHGTGKMLGERALKQAGFEQFVLVPEQAVADPDFTTVK
                     SPNPEEHSAFEYAMRLGEKEGADLLIATDPDADRLGAAVRLPNGSYEVLTGNQIGALF
                     AQYILEAHQSRGTLPENAAVLKSIVSSELPTAIAEHYGATMFNVLTGFKFIAEKIQQF
                     EEDHSHTFMFGFEESYGYLVKPFVRDKDAIQALLLLAEVAAYYKKQGKTLYDGLQTIF
                     ETYGYYAEKTISVTMSGQEGSAKISALMEKFREEAPTEFAGAKVIQTEDFKELTRTDR
                     EGNVEKLTTPPSDVLKYTLEENGWIAIRPSGTEPKIKFYIGVKGNSSEDAAEKVAAYE
                     AIIKKMTEE"
     gene            complement(16191..17117)
                     /gene="trxB"
                     /locus_tag="ACG8LA_000991"
     CDS             complement(16191..17117)
                     /gene="trxB"
                     /locus_tag="ACG8LA_000991"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004791 - thioredoxin-disulfide reductase
                     (NADPH) activity [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA];
                     GO_process: GO:0019430 - removal of superoxide radicals
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HFQ0203306.1"
                     /translation="MYDVIVIGAGPAGMTAALYASRSNLSVLMIEQGAPGGQMNNTAE
                     IENYPGFDSIMGPDLAYKMYEGVSRFGTENAYGIVQDIKDHGSHKEVICEDKTYEGKT
                     VIIATGCIHRKLGVPGEEEFAGRGVSYCAVCDGAFFRNKRLVVIGGGDSAVEEAIYLT
                     QFASEVVIVHRRDELRAQKIIQDRAFANEKISFMWDTVVDEIVGNEMVVTGVKARNVK
                     TGNEFDLAADGVFIYVGLDPLTAPFREAGLTNEAGWIPTDNEMKTNIPGVFAIGDVRE
                     KDLRQITTAVGDGGIAGQQVYKYLESLEETTA"
     gene            complement(17262..18695)
                     /locus_tag="ACG8LA_000992"
     CDS             complement(17262..18695)
                     /locus_tag="ACG8LA_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HFQ0203307.1"
                     /translation="MGFRKDFLWGGATAANQCEGGYDEGGRGLANVDVVPIGEDRFPV
                     ITGKKKMFEFDKDHFYPAKIAIDMYHHYKEDIALFAEMGFKTYRMSIAWSRIFPMGDE
                     NEPNESGLKFYEDVFKECQKYGIEPLVTITHFDCPMHLIKEYGAWRSRELVGFYENLC
                     RVIFNRYKGLVKYWLTFNEINMILHAPFMGAGLYFEEGENEEQIKYQAAHHELVASAI
                     ATKIAHEVDPENKVGCMLAAGAYYPYTCNPEDVWASRKSDRENYFFIDVQSRGEYPAY
                     ALKEMERNGIQIKMEPGDAALLKEHTVDFISFSYYSSRVSTTDNELLEQTAGNIFASV
                     KNPYLEASEWGWQIDPLGLRITMNDIYDRYQKPLFIVENGLGAVDTPDENGYVEDDYR
                     IDYLAAHIQAMKDTVELDGVDLLGYTTWGCIDLVSAGTGEMKKRYGFIYVDRDNEGNG
                     TLARSKKKSFNWYKKVIDSNGENLSND"
     gene            complement(18695..20098)
                     /locus_tag="ACG8LA_000993"
     CDS             complement(18695..20098)
                     /locus_tag="ACG8LA_000993"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008706 - 6-phospho-beta-glucosidase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HFQ0203308.1"
                     /translation="MAKGIKIATIGGGSSYTPELMEGFIKRYEELPIREIWLVDVEEG
                     KEKLEIVSQMSQRMWDASPYEVKIYATLDREEALKDADFVTTQFRVGQLDARIKDERI
                     PSYYGMIGQETNGAGGIFKAFRTVPVVLAIVEDMKRLCPNAWLINFANPSGMVTEAVI
                     RYGKWDKVIGLCNVPVMATMTEPAMLGKKKEELIYKFAGLNHFHWHKVADNKGNDRTA
                     DLIDRLYDEDNGLPKNIFDIPFFKEQLKQMNMIPCGYHRYYYREEEMLEHALEEYQTI
                     GTRAQQVKETEAELFELYKDPELDHKPEQLQKRGGAYYSDAACETIASIYGNKETQIV
                     VSTKNDGAVPDLPADCVVEVTAYVGAQGARNVAFGSLPAAERGWLQVMKNMELLTIEA
                     AVTGDYGTALQAFTINPLIRSGKTAKRIMDELFIAHQQYLPQFKETISRLKAEGIEVQ
                     DELARELSSNTHVMEEV"
     gene            20328..21230
                     /locus_tag="ACG8LA_000994"
     CDS             20328..21230
                     /locus_tag="ACG8LA_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HFQ0203309.1"
                     /translation="MLLREKIKEISFSPSENEVIQFLLSDSPALGEMTIQEIAERCYV
                     HPSTLIRVAKKMGFDGWVSFRNAFLAETAYLEGNFQDVDANLPFSTTDGIMTIANKMA
                     SLEQMTIQDTLSLIHHDQLQKAKQLMLQAKKIVIFASNSNTLISQDFMLKMKRIKMDV
                     TIVTTFGESFYEAYNCTSDMCGILISYTGENNVILRTAEILKQNHVPILALTSIGDST
                     LSSMSTAALRLTTRERLYSKIGNFTINTSICYLLDVLYSCVFAENYQQNLVHLISVGQ
                     KFDKRPISSAIMKEPFNFENKEVD"
     gene            complement(21271..23157)
                     /locus_tag="ACG8LA_000995"
     CDS             complement(21271..23157)
                     /locus_tag="ACG8LA_000995"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HFQ0203310.1"
                     /translation="MGKYQELARKIVENVGGKENINGLTHCITRLRFKLKNEEKANDE
                     ILKNMDGIVTVMRAGGQYQVVIGNHVPVVFEEVIKAGNLTFDEAVSTEKMRPFDMLID
                     GISGCFQPFLAILAAGGMIRGLTAFLVFLGAFDRGSGTFVMFDNIGDSVFQFMPVIIG
                     LTAARKFKVNEFVGMLLGAALMNPSLSLEALSGAAEAPLTTIFSGTIFEAPIYQTVFG
                     IPWIARNYASSVIPIIFIVLLASQIQKPIKKLVPEMIANFFVPFFTVLITMPLGFLLV
                     GPVFTFATDILMAGFETLLALSPVIYGAIVGFFWQILVMFGLHWAIVPMGLMQFSVNG
                     WQNIMTPVAVVSFGQTAALTALYFKLRNPKDKAIAIPAIVSGIVGITEPAIYGFTLPR
                     KKIFIFTCVGGALGGAYSGLMNLTSWNQGGLGIFTIPNYIRPDGDLTDVINVLIGIAI
                     AMVVSFALTFFFWKEEAGETDDRQKRSGKEIVKTPIQGQIAPLKAAKDAAFAQGTLGR
                     GILIYPEKGEVRAPFDGTVMTLFPTKHAIGMVSETGLELLIHVGLDTVQLEGKYFESL
                     VQQGERVKQGDLLLRFDKKKIEKEGYSLETPVIVTNYMDYLDILENQGETVGPDDALI
                     TALT"
     gene            complement(23254..24105)
                     /gene="licT"
                     /locus_tag="ACG8LA_000996"
     CDS             complement(23254..24105)
                     /gene="licT"
                     /locus_tag="ACG8LA_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator LicT"
                     /protein_id="HFQ0203311.1"
                     /translation="MLIEKVLNNNVVITRDERNQEMIVMGKGLAFKKKVGDPIFDSCI
                     DKKFQLTNDGLSQQFQELAQAIPLEYLEISCEIIEYTKEALQVQLNDSVYIALTDHLY
                     TAIERHKMGIFVPNVLLYDIKQLFPKEYAIGKKTVKKISDKYHIKLSEDEAGFIALHL
                     VNAQGIQSQQNNTYLFTITIQDILNIVRYYYKITFDEDSVHFFRFVTHLRFFLTRVLD
                     GEKSEVGEVSEELFQVIQKKYKDTFGCVEKIADFLAETFNYQMSTDEKMYLTIHTARL
                     VHENRCK"
     gene            complement(24428..26212)
                     /locus_tag="ACG8LA_000997"
     CDS             complement(24428..26212)
                     /locus_tag="ACG8LA_000997"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0203312.1"
                     /translation="MDENYQSEWTKSIPLKEQKKIIKRLMKFAKPFRRTFIVAILFAF
                     ALSVINVLLPRIIQTFMDDHLAKQSATTQVILFFAGVYLFGVIVKSIIWFFQWYLYSM
                     ASLKTYQYVRVRLFEKLHTLGMRYFDQTPAGSTVSRVTNDTETLFEFWYVFLMVLTGI
                     FAVVSSFVAMFQINGEIALWTLVFLPILGIVIWYYQKFSSRIYRNMREKLSQLNTKLN
                     ESISGMRIIQQFRQEARLAKEFEQVNNEYLDTRYAMIKTNSILLSPIINFLYALAIAL
                     ALTLFGIDALHSPVEVGLIYAFTTYVQGFFNPMSQMMDFLSTFTDGMVAGSRILKIMD
                     TEEYAPQQNPGADQAITSGKIEFRNVSFSYDGEHNVLNNISFVANPGETVALVGHTGS
                     GKSSIINVLMRFYEFYEGQILIDDHDIREYPMEELRKKMGLVLQDAFLFYGDIAGNIR
                     MMNPAITDEQIRHAAEFVQANKFIDELPKGYHSKVIEHGASYSSGQRQLITFARTIVT
                     DPKILVLDEATANIDTETEGLIQEGLAKMRQGRTTIAIAHRLSTIRDAELILVLDKGH
                     IVERGNHETLLAQNGLYADMYKLQSSGV"
     gene            complement(26212..27963)
                     /locus_tag="ACG8LA_000998"
     CDS             complement(26212..27963)
                     /locus_tag="ACG8LA_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter transmembrane domain-containing
                     protein"
                     /protein_id="HFQ0203313.1"
                     /translation="MSIFRKLGWFFRQEKKHYLIGIFSLFAVALVQLVPPKVIGIIID
                     EIADKNLSIKIISWWILLLILAAFLQYLFRYIWRTNIWGSAARLEKELRQQLFKHFTE
                     MDNLFYQKYRTGDLMAHATNDLNAIQNVAGAGILTFADSVITGGTTIIAMILFIDWRL
                     TLIALIPLPLLAVTSRVLGSKLHDAFRDSQEAFSSINDKTQESITGIKVIKTFGQEKE
                     DLADFEEKIEDAIIKNKRVNFLDSLFDPFITLIIGLSYVATIILGGKYVLEGTISIGQ
                     MVSFISYIGMLVWPMFAIGRLFNVLERGNASYDRVNELLHEKTHIVEQLGAVQTPAKG
                     ELNVAISSFNYPKEESPALEQIKFAIQEGETLGIVGKTGAGKTTIIKLLMREYDDYQG
                     KIQFGGRSIKEYSLNALLGSIGYVPQDHFLFSMTIRDNIRFSNPKLSEEEVEHAASLA
                     FINNEIKELPKGYDTLVGERGVSLSGGQKQRISIARALIKNPELLILDDALSAVDAKT
                     EEAILHNLKEIRKEKTTIIAAHRLSSVMHAKEIIVVDQGKIIERGTHHELLALGGWYE
                     RMWEKQQLEAKIEGGEA"
     gene            complement(28105..28329)
                     /locus_tag="ACG8LA_000999"
     CDS             complement(28105..28329)
                     /locus_tag="ACG8LA_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HFQ0203314.1"
                     /translation="MVSTGIVVLIAIIALLIGAVGGFFLARKYMKDYLEKNPPVNEDM
                     LRSMMMSMGQKPSEKKIRQMMQQMKNQGKK"
     gene            28580..30166
                     /locus_tag="ACG8LA_001000"
     CDS             28580..30166
                     /locus_tag="ACG8LA_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Nramp family divalent metal transporter"
                     /protein_id="HFQ0203315.1"
                     /translation="MNNQSNKQFHKHRLIEHTNGLSLAEVNGTVDVPKGKSFFKTLLA
                     YSGPGALVAVGYMDPGNWSTSITGGQNFQYLLMSVILMSSLIAMLLQYMAAKLGIVTQ
                     MDLAQAIRARTSKTLGVILWILTELAIMATDIAEVIGAAIALYLLFDIPLVIAVFITV
                     LDVFVLLLLTKVGFRKIEALVVCLIFVILFVFVYQVGLSNPDWHSLFAGFIPNSHTFS
                     DSPVIGGETPLTGALGIIGATVMPHNLYLHSAVSQTRKIDHQDEEDVAQAVRFSTWDS
                     NIQLSMAFLVNALLLIMGVAVFKTGSVQDPSFFGLYEALSDPSAMSNGILIAVAKSGI
                     LSTLFAVALLASGQNSTITGTLTGQVIMEGFIHMRIPIWLRRLVTRLLSVIPVLICVL
                     FTSTKGTIEEHTALNNLMNESQVFLAFALPFSMIPLLMMTNSQAEMGSRFKNSFVVKL
                     LGWFSVISLTYLNLRGLPGQIESFFGEQATSAQLALADQIAYVIIVLVLLLLAWTIGD
                     LYKGNKKYEQRLQETIEEIE"
     gene            complement(30475..32250)
                     /locus_tag="ACG8LA_001001"
     CDS             complement(30475..32250)
                     /locus_tag="ACG8LA_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosyltransferase"
                     /protein_id="HFQ0203316.1"
                     /translation="MLNILNPLIDQLKKKHTYFILGIAVLFTIIRLYLYSKAIYGTDM
                     SATYDDQLLIHYAQNILDGKWLGEYTTTTLSKGISYSLFLVLAHKLHLSYAVLFGMFS
                     ILASILVALAFKPIVKNKYLLLSIYFYFLFSPISFTHEYSTRTYRNALVIPTVEIIIA
                     CLLAIYYRKYNSSKKLLPWFLGLAVSFPFFWFIREDSIWLLPFTVVALGISFVQILLG
                     QDFSFKEAKKLKERPFLLSKQEWLKLSLFLLPLVGFSIVYQWIEYKNETTYGIAAIND
                     RSSGEFGRLMKQLIRIDDETNLNKENSEIWVSHAALNKALDASPTFHTVSTRIDELYT
                     THAWTQGGKVKELPGDIIFWALRDVVSESGYYQNNAKETNDFWKKVNQELEEAYQKGT
                     IKKKKEFYLMGSGDGKTMNDLPIVFDFLKSGYAYAWRYKDFHQGGNYSFGTQEQVEQA
                     QELLNLPLMDNWIDSSDPRTPDFQLTKTAKVANVMIKIYQVLAIPVLIASIAGILLMI
                     LGTVFAKADRAYYSSSLIVVIGLILTQLVFLFGVSWFCSYAPEKKDYFLSVYTGAGVP
                     LTQFIAVTSMLVFSKLNLKKALSSK"
     gene            complement(32461..33363)
                     /locus_tag="ACG8LA_001002"
     CDS             complement(32461..33363)
                     /locus_tag="ACG8LA_001002"
                     /EC_number="3.1.21.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HFQ0203317.1"
                     /translation="MLLGSHVSMSGKKMLLGAAEEAASYGSSTFMIYTGAPQNTRRKA
                     IEEMNIDAGKAFMAENGLTNIVVHAPYIINLGNTIKPEMFPFAVQFLREEIVRAEALG
                     ATQITLHPGAHVGAGAEAGIARIIEGLNEVLTKEQTAQIALETMAGKGTEIGRTFEEL
                     AQIIDGVKLNEKLSVTFDTCHTNDAGYNIKEDFSGVMEEFDKVIGLDRLKVLHINDSK
                     NPQGSHKDRHANIGFGTIGFDTLNKIVHDPMFDNISKILETPYVGKDKKKAYAPYGKE
                     ISMFKAQAFDPEVFPELLAEEVTL"
     gene            33642..35987
                     /locus_tag="ACG8LA_001003"
     CDS             33642..35987
                     /locus_tag="ACG8LA_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase domain-containing protein"
                     /protein_id="HFQ0203318.1"
                     /translation="MPRKNTRKKQNRRKKEKWFVPKIIFRVFQSLTVFITVLLLLFAA
                     LGIGIGAGYFAYLVEDTQLPTKKELQTELGNITETSKIVYADNTEISKIQTDLMRTTI
                     SSDKISPLLKTAIISTEDEYFDKHQGYVPKAVLRALVSEATGIGSSGGSTLTQQLVKQ
                     QILTDETTFKRKANEIVLSAQVEKHFSKDEIITTYLNVSPFGRNNKGQNIAGVQEAAR
                     GIFGVDAKDVTLPQAAYIAGLPQSPITYSPYTNTGALKEDLSAGLARKDFVLFSMYRE
                     GQITKEQYEEAKAYDLTKDFLPQQIAEQTDREFLYYTVMNEATRIIAQQLAEKDNADM
                     SDSSVSEAYYQKAQQTIQNKGYTIHSTIDKDIYAALQTGVENYGYMLDDGAGSQVETG
                     NVLMDNRTGRIYGFVGGRNYSQNQNNHAFDTERQAGSSIKPVLVYGPAIDMGLVGSES
                     RVSDYATTWQEGKNAGEKIVNATNEGSNTFQTVRESLEWSNNIPAYHLYQDVLNSGGS
                     KQYAYEHYLAKMNYPANDNWGVESAPLGTVDVTTLQQTNGFQALANGGVYEEGYIIDS
                     ITDNAGNVIYKHESNSVRIYSEATASIMNDMMRSVINEKITTPFKDVISSLNGNLGNA
                     DWVGKTGSTNEYRDSWLIVSTPSITISSWAGHDDNTGMDSQARIRSANYLANLINQAY
                     QANPEIFGTDEKFDLSSDVMKKKVSGFTGQTAGKVTVNKKSIQTPGKTVESLWAKNGP
                     KKSAFKFGVGGTDENYTDYWNTASAYARANPETKESDDKDD"
     gene            complement(36150..36416)
                     /locus_tag="ACG8LA_001004"
     CDS             complement(36150..36416)
                     /locus_tag="ACG8LA_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0203319.1"
                     /translation="MNEFLMQLLKELEKNLHRSNVRSVGMGISQQTWAEKRLTDQNHQ
                     MTAEEATQEFSNRHAHLKESVKGQFAEKLTELFQRQEKKLKQFR"
     gene            complement(36409..36732)
                     /locus_tag="ACG8LA_001005"
     CDS             complement(36409..36732)
                     /locus_tag="ACG8LA_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0203320.1"
                     /translation="MKLEELERDYRSERRQLEAQEDELIHFKNQGLRLMEQEEQRLHH
                     VLKNLALDNEPLFQARRSYSNYQEHYQQALQVERRKLYQQQDELERSYRQKIRQITME
                     KSSYE"
     gene            complement(36744..38000)
                     /locus_tag="ACG8LA_001006"
     CDS             complement(36744..38000)
                     /locus_tag="ACG8LA_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipase"
                     /protein_id="HFQ0203321.1"
                     /translation="MTITDKQYKGISNKVYWLDPKHPQYSKSYKEGAIKNFGETKFQI
                     LKIKNSFDGMQAMAVAPIKNGKVDISQVVIAFAGTNLSDWKDLETDARSVMNLYGNRP
                     GASFSEKATTNKILSVSGLKTAGQINSAIAFANEVKKEYGEAAISTTGHSLGGFLALY
                     VAAEKQWKNVGFNGPDPYDLLSPEAKKWVEENPGMLTNYRNHADFIGNFGGNGTGAEV
                     RISMETAYLNLLASHSLTSWKFDENGKLIIPENENNVKARKQQKENQATQLFSYQLQE
                     LNNIRKKLRLSGGRLTVNEQIYLDDTQARLVVEKLSVKMKSAMEEVIRINQRGIFELE
                     KKWQEGLRQARVVAPSLTEQEIIEALASVGATKENLVDSAKEVYLLRINKARRMGEAF
                     DTLAKEIQDKINEIVARDRELAQQFN"
     gene            complement(37997..38392)
                     /locus_tag="ACG8LA_001007"
     CDS             complement(37997..38392)
                     /locus_tag="ACG8LA_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0203322.1"
                     /translation="MPKKRRKTIVIILTILTIGIGGKFYMDKREAQKQQDLLAVEKQS
                     VKVLKNTFADIKEVKIEQFEKNDMTGIYEALITMTNTEGKAVYFDYSFTKESNEIDGY
                     GVENEEVQKEGITVDEIIVIYTDGSEEKV"
     gene            complement(38746..39747)
                     /gene="ccpA"
                     /locus_tag="ACG8LA_001008"
     CDS             complement(38746..39747)
                     /gene="ccpA"
                     /locus_tag="ACG8LA_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0001228 - DNA-binding transcription
                     activator activity, RNA polymerase II-specific [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HFQ0203323.1"
                     /translation="MEKQTITIYDVAREANVSMATVSRVVNGNPNVKPATRKKVLEVI
                     DRLDYRPNAVARGLASKKTTTVGVIIPDVSNMFFASLARGIDDVATMYKYNIILANSD
                     GNDQKEVNVLNNLLAKQVDGVIFMGHHITDEIRGEFSRSKTPVVLAGSIDPDEQVGSV
                     NIDYVSATKDAVNKLAKSGNKKIAFVSGALIDPINGQNRLKGYKEALSENNLPYSEGL
                     IFEAQYNFKDGLSLVDRIHNSGATAVYVSDDELAIGILDGLLDRGVKVPEEFEIITSN
                     NSLLTEVARPRLTSITQPLYDLGAVSMRLLTKMMNKEEVEEKTIILPYGIEEKGSTK"
     gene            39957..41060
                     /locus_tag="ACG8LA_001009"
     CDS             39957..41060
                     /locus_tag="ACG8LA_001009"
                     /EC_number="3.4.11.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004177 - aminopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HFQ0203324.1"
                     /translation="MNNVKINELRQWMAQHQLELAYISDPGHIAYFSGYESDPHERVL
                     ALFIPLEQDPFLFTPALEVEDAQNSSWAYDVRGYLDSENPWEIIGKELRARYGQPGNV
                     GIEKNALTVDRFDAISDILTGTDSYTDLTSIIQRLQLIKTVEEKDKLIEAGKWADVAF
                     EIGFKTVKEGVTEQAIIAEIEYQLKKQGVSQMSFDTLVLAGANAASPHGTPGSTKVSP
                     NELVLFDLGVIWNGYCSDATRTVAYQKPTEFQEKIYNITLEAQLAAQEAVRPGVTAGE
                     LDQIARNVINSYGYGEYFNHRLGHGIGTTVHEFPSLVEGNDLVIEEGMCFSLEPGIYI
                     PEKVGVRIEDCVYVTSDGCVPFTTTPKELLVLE"
     gene            complement(41123..41737)
                     /locus_tag="ACG8LA_001010"
     CDS             complement(41123..41737)
                     /locus_tag="ACG8LA_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HFQ0203325.1"
                     /translation="MAKKGGFLLGAVVGGTAAAIAALLLAPKSGKELRDELAAQADDL
                     MDMASDYTDMAKEKSSELTGIAKEKAQDLSQQAGDLAGNVKQKVSESAEEAGSESDDI
                     LLNLKEQSADLSNRFKKTAEDLKKPADELGSIAKDTSEDIMIDVKDAADKAGETVNEG
                     MSEAKPVADDTKEMLKMAKEDAKEDAKEAKKEMKDTMTDSTTNH"
     gene            complement(41730..42179)
                     /locus_tag="ACG8LA_001011"
     CDS             complement(41730..42179)
                     /locus_tag="ACG8LA_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003126235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HFQ0203326.1"
                     /translation="MSGGEIAGLIAAIAFAILVVFIVRVLLQVSKTLEKVDQTVAEAN
                     TTIEIVTQDVDLLSRQVEGLLVKSNELLLDINGKVATIDPLFTAVADLSESVSELNHS
                     SKNIVTKVGGIGKTTAKATVAGKVGGTAMKFLKTKNILKRQEENKNG"
     gene            complement(42304..43242)
                     /gene="galU"
                     /locus_tag="ACG8LA_001012"
     CDS             complement(42304..43242)
                     /gene="galU"
                     /locus_tag="ACG8LA_001012"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003983 - UTP:glucose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0006011 - UDP-glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HFQ0203327.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LKSGIEDILIVTGKAKRPIEDHFDSNIELETNLSEKGKTELLKLVEETTDVNLHFIRQ
                     SHPKGLGHAVLQARAFIGNEPFVVMLGDDIMEDEVPLTQQLIDDYERTHASTIAVMQV
                     PHDETSKYGIINPGEVLEDGLYNVKNFVEKPDPSKAPSDLAIIGRYLLTPEIFDVLSE
                     QQPGAGNEIQLTDAIDTLNKTQRVFARKFTGKRYDVGDKFGFMKTSIEYGLTHPEVGA
                     PLREYIMSLGKTLEAEGSKINHNPKGITEIKEEKKK"
     gene            complement(43257..44282)
                     /locus_tag="ACG8LA_001013"
     CDS             complement(43257..44282)
                     /locus_tag="ACG8LA_001013"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009331 - glycerol-3-phosphate
                     dehydrogenase (FAD) complex [Evidence IEA];
                     GO_function: GO:0047952 - glycerol-3-phosphate
                     dehydrogenase [NAD(P)+] activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0046168 - glycerol-3-phosphate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HFQ0203328.1"
                     /translation="MNYRVAVLGPGSWGTALAQVLAENGHDVRIWGHRASQVEEINTQ
                     HTNQRYLPDHHLPDSIRAFTDMEDAVKDADAVLFVIPTKAIRSVAKELVAKLNTKPVI
                     IHASKGLEQGTHKRISEILLEEIPTEKRKAVAVLSGPSHAEEVAKHDITTITAASTNV
                     KAAKYVQELFMNHYFRIYTNPDVIGVEMGAALKNIIAIGAGAIHGLGFGDNAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLVVTCTSVHSRNWRAGNLLGQGQPLEEVLA
                     NMGMVVEGVNTTQAAMELAQMMEIEMPITQTIYEVLYEQKEIKTAAKEIMLRDGKKEN
                     EFSLTIF"
     gene            complement(44326..45156)
                     /gene="lgt"
                     /locus_tag="ACG8LA_001014"
     CDS             complement(44326..45156)
                     /gene="lgt"
                     /locus_tag="ACG8LA_001014"
                     /EC_number="2.5.1.145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008961 -
                     phosphatidylglycerol-prolipoprotein diacylglyceryl
                     transferase activity [Evidence IEA];
                     GO_process: GO:0009249 - protein lipoylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HFQ0203329.1"
                     /translation="MLAQINRVAFELVGIPIYWYALIIVSGIIIAMWLSSREAVRVGL
                     KADDVTDFMLWGLPISIIGARLYYVLFDLPQYIADPIQIFNIRSGGLAIYGGLIAGAI
                     TLYFFTKYHFISLWTFLDIAAPSVLLAQAIGRWGNFMNHEAYGPDTTRSFLESLHLPQ
                     FIIDNMYIEGIYRQPTFLYESLWSLIGFILLLVLRKKPHLLKKGEVLLCYLMWYSFGR
                     FFIEGLRTDSLYFLGVIRISQLLSAVLFVGTLILFIWRRKKGSLPDYDRSLGKNQQII
                     "
     gene            complement(45171..46109)
                     /gene="hprK"
                     /locus_tag="ACG8LA_001015"
     CDS             complement(45171..46109)
                     /gene="hprK"
                     /locus_tag="ACG8LA_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006109 - regulation of carbohydrate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HPr(Ser) kinase/phosphatase"
                     /protein_id="HFQ0203330.1"
                     /translation="MSEVVKVSQLVKKLSLEIVTGDEKSLDRVIVTGDISRPGLELTG
                     YFNYYSHNRLQLFGSKEISFAERMIPEERLIIMRRLCSEDMPAFIISRGLPAPEEMIQ
                     AANENGIAVLRSPISTSRLLGELSSYLDGRLAPRTSVHGVLVDVYGLGVLIQGDSGIG
                     KSETALELIKRGHRLIADDRVDVYQQDELTVIGEPPKILEHLIEIRGIGIIDVMNLFG
                     ASAVRGSMQVQLAVYLEAWAKDKKYDRLGSEDTTVEIAEVGIPQIKIPVKTGRNVAII
                     IEVAAMNFRARTMGFDATKTFEERLSRLIEENSGND"
BASE COUNT        12915 a         9896 c         8324 g        15104 t
ORIGIN      
        1 cagagacaca gcacgtttcg tgcatgctct ctgtttttca aacaaaagac tattttgtga
       61 tgatttgatc caagcttgct aatgacaaag ccatggcagc tatttgacta agttgtgtta
      121 gtcggttctt acgtactgct ggttcatcag ccatgaccat cgtttgatca aaataatttt
      181 cgatcagtgg acgaagagcg acaagctggt cgtagttttc gtggatcgtt tggtcagcaa
      241 aacttgcttt cattgcttct actgctttgt gtaattcttt ctctgcgtcg ttttcgaaca
      301 gctcaggatc tacttctgat tgtttttcaa gctgcgcttt tttcgctaag ttcacgacac
      361 gtgtcaaagc ttccattgaa ggtttgaagt cttcatctgc aagatgttgt ttgaacaatt
      421 gtgctgctgc aaatactttt gtcagatctt tttgttccgc attcaaaaca gcatcgatga
      481 catcatgacg aatattcttc gttgtcaata attggcgcag acggcctttg ataaagtcga
      541 tcacttgttg ttgcccttct gataaaccaa tgccgaaacg atccgtatct ttactgataa
      601 catcgctaat cgtttcttgc agaacagaca aaggaaaggc ccattttttc gattcgatga
      661 tccgaacgac accgtatgct tggcgacgta aggcataagg atcgtttgaa ccgcttggga
      721 tcatcccaac agcaaagaaa gaaaagatgc tatctaattt atctgcaatc gctaaaacag
      781 aacctactgt agactgaggt agctctcctt cactggatat aggcatgtaa tgctcacgaa
      841 tcgctgtcgc tacagcaggt ttctcgcctt tcagcagagc atatttttcg cccatgatcc
      901 cttgcagttc aggaaattcc cctaccatgt tggttactag atcaaattta tagatttcag
      961 cagctcgttg cagatccatc aattcttcct cagatagtcc tacttgttcg ccaatgatac
     1021 gggcaatgac ttgtacccgt tgcattttct catagatact accgattttt tcatggaaag
     1081 taacagtttt tagtttttca acgtattggt cgattgaagc tttcttgtct tcattataaa
     1141 agaattccgc atcttctaaa cgagccgtca atactttttg attgcctcga accacatttt
     1201 ccaattttac ccgatcacca ttacgagcag aaataaaatg aggaagcagc ataccttgat
     1261 cattccgtac ctcgaaataa cgttgatgtt ctttcataga agtgactagt acttcttcag
     1321 gaacagaaag atatttttct tcgaagtcgc cagaaaagac agttggatat tcgactaaat
     1381 tgttgacttc ttctagtaaa tcttcgtcta gatcaataac ccaatgattt ttttcggcta
     1441 attcattggc ttgtgtaacg atcatttctt gtcttttttg cggagacgca atgacgaatt
     1501 gttcattcaa tttttcttca tattcttttg catgcgcaaa tgtcacatct tcgcctaaga
     1561 aacgatgacc tcgagaggct ctgcctgttt tgacatccaa gatttcgaat gggattactt
     1621 cgtcatctaa caatgccacg atccagtgaa tagggcggat atattcaaaa tcgtattctg
     1681 cccaatgcat cgttacaggg aaagtcaggc ttttaatgac atctgctaaa cctgtcaata
     1741 cttctttgga ttccttacca tgagtgtatt tcgttacata gacatattcc acacctttta
     1801 attctctaaa agtgatagcg tctgtcgtca gaccttgtcc gcggacaaat ccttccgctg
     1861 ctttcgtcca gtttccatct gcgtccaaag caattttttt ggctggtcct ttgacttctt
     1921 cttcactgtc cgcttgtcgt tctggaatgt ttgttacttt gattgctaaa cggcgcggtg
     1981 tggaaaatgt ttcgatcgta tcataagtca attggttttc atctaaaaat tttgctgttt
     2041 tttcttctaa ttgtttcatg cttggtgtga caacatgagc aggcatttct tccagcccga
     2101 tttcaagtaa taagtctttt gccatcttat tcagcctcct tcacgttttc tggatttgct
     2161 gtgtttttat tcaacaaagg gaatcctaat ttttcgcgtt ctgccacaaa gattttggct
     2221 acagcacgag ccatgttgcg gatgcgagaa agataaccgg cacgctctgt tacggatact
     2281 gcaccgcggg cgtctaataa gttgaatgta tggctacatt tcaagatata atcatacgcc
     2341 ggatgaacaa gattttcatc gatacagcgt ttagcttctt tttcaaaacg atcaaagttg
     2401 cttagtagca agtcttggtc gcttacttca aaagaatatt tagaatgttc atattctggt
     2461 tgtttgaaga tctcgccata tttcacgcca tcagcccatt ctaaatcata gacactttca
     2521 acttcttgga tataagaagc aagacgttct aatccataag tgatctcaga agttactggt
     2581 ttacaaggca gtccaccaac ttgttggaag tacgtgaatt gtgtgatttc cattccgtca
     2641 agccatactt cccaacccac accggcacag cccatggatg ggttctccca gttgtcttca
     2701 acaaaacgga tgtcgtgttc tagtggatcg attcctaaaa ggcgcaagct ttctaaataa
     2761 agctcttgga tattctcagg tgaaggtttc atcacgactt ggaattgatg atgctgatac
     2821 aaacggtttg ggttttcgcc ataacgtcca tcagctggtc ggcgagatgg ctctacgtaa
     2881 gcagcattcc atggttctgg tccgattgcc cgtaaaaagg tatatgggct catcgtacct
     2941 gctccttttt ctgtgtcata cgcttgcatc agcatgcagc cgtttgatga ccaaaatttt
     3001 tgtaatgtta aaatcatatc ttggacggtc aattttttac tcatctgttt tgcccctttc
     3061 aattttaaag cgttgctgtc aaataagaat acaggaaaga aaacgacaaa aaatccctat
     3121 gtctgattac agacataggg acgaataatt cgcggttcca ccctacttcc gaataaagat
     3181 tcggcagctt catttatcgt actcgcaagt gcctcttcaa aaatcgtttg ggtccggctc
     3241 ccactctccc gaactcgcta aaccacgtgt tttttactga tcttggtcaa tgtacgtatt
     3301 cattttgcag ttttcttgtt tctataatag atcctctcag tgaacgatct atttgatcta
     3361 cggttaataa tagacggaac tccctgtgtt tgtcaaatgg ttttgatttt ttgttgtatg
     3421 tttcatttac tattcttctt ttttaggtag atctttttca gacatgtctt tctctgacgt
     3481 ctttaatacg tgtgcccaag acttcatttg atcaatgaac tttttgcttt tcaaatggat
     3541 accgacatat tcatcataca gctggtcgat gagttcacgg attgcttgtt tggtttcttc
     3601 tttcagatgg attccactga ttttatcata agaaatagct gaaaacatcc gaacgaaata
     3661 aacagctcga ggatctgcat gataacggtg atcatccatc gaccagtgtc tttcgcatat
     3721 cacaccacca tatttggaag aatagtcaaa ttttcctttt gtttccccac atacgacgca
     3781 gtgtgtccag attggtgcaa ttccgaagcg ttgcagtatt tggacttcaa aaatattcgt
     3841 gatgatttct gcatcatctc cttggtccat ccgttgcagt gcttgttgcg taaactggaa
     3901 caaatgcggg tcgtactgat gatcttcgat tgccgcatct actagattca ataaatatgt
     3961 gccatagccg ctcaaaaaga tgtcttcttg gatgtgtcga aacgcgtgga catctttgac
     4021 actgcttaaa aatgacaaac cttcacttcg aaaattcccg atataaactg cttcagtaaa
     4081 agggagcaaa gccggagcta agggctgatt ttgccgatgg atccctttga tataaaacat
     4141 cattttgcca gaagattccg taaagatttt gactaattta tctttttctt tgtaattacg
     4201 gctagataaa atcaagcctt ttgattctgc aagctggctc atattctccc tcctaaaaaa
     4261 taaatctgga aaagcagatt ctgccgatcc agatcattta tgttgcgatc ttccgcagct
     4321 tttctcaaca cgcggatttt tatccagttt atttctatac ctaacttaca agaagctcag
     4381 aatatcaata ttcgtctttt cggtagccga agtcttgcag atagactttt ttgtctcgcc
     4441 agtctttttg aactttgacc caaagttcta gaaagacttt gtctcctaaa agattttcga
     4501 tatcttttct cgctttcgtt cctacttgct tcagcatttt tccgcctttg ccgataatga
     4561 tccctttttg gctatctctt tcgacaataa tcgtagcctg gatatggatt ttatcattct
     4621 cgtttcgctt catcgaatca acaacgactg cgacagaatg aggcacttcg tctcgtgtta
     4681 aaaacaagac tttctcacgg atcaattcag aaacgatgaa gtattcagga tgatcagtca
     4741 cttgatcatc tggaaaatat tgtgggccct ctggcatttc actgactaat acatccatca
     4801 aacgttcgac gttgtttcct tctgtagcag aaattggaat cacttgtgca aacggcatct
     4861 gcgttgaata atcttcgatg attcccaaca actcgtctgg atggatttta tcgattttat
     4921 tgataatcag ataaacagga gaatgcacgt tttttagacg ttcaataata aaatcgtctc
     4981 cccgaccgcg tttttgatca gcgctgatca taaataagac cgcgtccact tctttcaacg
     5041 cactgtaagc tgcttctacc ataaaatctc ctaaacgatg ctttggttta tggattcctg
     5101 gtgtgtcaat aaaaatcaac tgagcttctg gtgtagtata tactccttgg attttatttc
     5161 tagttgtctg cgccttatca ctcatgatgg caattttttg acccacgatt cgattcaata
     5221 atgtggattt tcctacattc gggcggccga cgattgcgac aaaccctgat ttatgttctg
     5281 gcatatacgt tctccttttt aattaaacaa caaatgatat attttaggga caaataaaat
     5341 caacccaacg atgacggaaa aacaagcggt cactaaaact gctccagctg ccatatcttt
     5401 gatttttttc ccaatcggat gaaaatgaaa atccgtaaac atgtccacga cattttcaaa
     5461 aacagtattg atgatctcta ctatccatac gagaaaaaca gctaaaagca gccataacca
     5521 ttctatccga tcaagctgga aaatcacgcc cataaacaaa gcgaggattc cgaacgcaac
     5581 atgtttcctc atgttgcgtt cttcctcaaa aacggttttg actccttgga cggcaaattc
     5641 cacggacatc aggaaatgtt tgtttttctc tacgttttta tcttttaagt ccataggcat
     5701 ctaagatctc tttctgtaaa ccaaacattt ctttctcatc ctctggtgtc atatggtcat
     5761 acccgttgat atgcaagaat ccatgaaccg ctaaaaagcc aagttcccga tcatacgaat
     5821 ggccgtaagc ttctgcttgc tctgcagcac gttcagtaga gatcatgatg tctcccagta
     5881 cacgaggcaa tggattctct ccatcttcaa aaatcactgg gatttcgtct tcgccctctt
     5941 cttccaaggc aaaactgatg acgtctgtcg gtgcatcttt tccacggtaa tcacgattga
     6001 ttacttggat cgctgcattg tccatgaaag taacagacat ttctgtttct tctggcaact
     6061 ctaaatatga tgctgcaaat tgcagcaagt cgtcgatttc tttcattttc tcttctgaga
     6121 cttggtttgt ttcatccatg aaagtaatat ccattataca tcgcttcttt ctattcttct
     6181 tgttcttctt ttatcttctc aacttccgat ttcattttag gatatttgat ccgagaatgg
     6241 aaggtactgc ttaaaccgct gatcaatgat ttttctactt tacggatttc ttttaacgtc
     6301 aatccactgt cgtccaattg tccatcggaa atacgctctt caataagatt atggacaaaa
     6361 ctttcgattt tttcgctcgt tggatggtcc attgctcgta ctgccgcttc acaactgtca
     6421 gctatattga cgattcctgc ttcacggctt tgaggttttg gtccaggata acggaattgc
     6481 tcttccgtga cttccgggtt gcgttccttt gccttaacgt agaaataacg catcagcgtg
     6541 gttccatgat gctgtctgca aatatcgatc accatttgcg gcatattata atcttccaat
     6601 attttggcac catctgtcac atgtccaaag ataatatgtt tactgtcttc tggcaataag
     6661 aaattgtgcg gattttccgc tcctgaaggc aagttctcaa cgaaaaagct ggcgtgtttg
     6721 atcttgccga tatcatgata atagcaagct actcgagtta gtaaagaacg tccaccgatt
     6781 tctgctacag cattagcact tagattggct accatcatgc tatggtgata cgtgcctggt
     6841 gcttcttcca gcaactgttt caataaagga tgattaggat tgctgagttc atttaatacg
     6901 atcacactat catcattgac catcaattca atataggggt gcagacctat cgtcagcaag
     6961 aatgagaaca gtgcacctgt gaatccgcat actagcgtta accaagtcgt tgcatcccca
     7021 aagctcattc cttggtagat aatcaaaatg acatccatca tcacaggaaa aataatgacc
     7081 cacatagcag cggataaccc ttgttctgag atccgtttgc gtctgacgat cgttgccatg
     7141 agaccagaaa atacatagga catcaaaata actgtcagaa agttcgtgcc aatcgaatca
     7201 taaaaaatga aaagtgcgga tactgcttga aaaataccag ccatgatccc tgctcttcga
     7261 ttcaagaaaa agcttaaaac aagtggagca aaagccgcgg ggtaaaacag cggaatataa
     7321 gcagcttgtt ctgtttggaa gagttggaaa aatttcatta gtacgacgct tactgacatt
     7381 gccgtcacgt agaaaagtac gtattttgtt ctttctcctg cattttggaa ttgaagtgaa
     7441 ttataaatca gtacaccgat ttgaagcaaa acagctaaaa ccatggcaat gagtgggaaa
     7501 atagaagtcg tttgattcgt caatcctagt aattccaatt ttttcatcgc tgaagcatca
     7561 atttgatttc cttcgcgaac aataatttct ccttggaaga tcatcactgg ttgtacagct
     7621 tctcgtgcag attgttttaa ttcttctgtc tttttctcat tcaatacatc attaactaca
     7681 atgccttgat ccactaagta gcgaatcatt tgttgctgct ctgttgtgac attcaaatat
     7741 tgaatctgat cttctgcttc ttgtttaaaa gcttccaatt cgctttcacg aacttgttta
     7801 ctcatctgtt cgtcaatgag cttcaaactt tcatccctaa ccgtgtgaat ttccgtttca
     7861 gtcatttcaa atatcgtcga ataaaaattg ttcggcagtt tttggtaaaa cgcaacgttt
     7921 tctgcattca cgttttcaaa atttttcttc agtgtagcaa tccgctcttc tgtagtaggt
     7981 ttcgggatat tttcatcttc cttcgcctta tctaccttgt cattataaga tttgttgatg
     8041 gtatcattcg tcttatcgat caattcgaat aattgcttga tccgattgtt ctggtcatct
     8101 gccagatctt tttgataagt atattctgga gtcactgctt ctgctgccag ttttcttctt
     8161 tgttcggttt cttccgtgtt ctcaatcgtt ttattcgcac ggatactctc ttctgctact
     8221 tggccttctc tgaaatcatt ggccttttgt ttgacactac taaatgtaac gccgcagaca
     8281 atgataaaaa acaagaacag aaggaaaggc aatgctgcct ttccgagttt ttcttgtagt
     8341 ttctgcagtg ttttattcaa catgtgctta tcctcctaag caaagcttat tcttgatgaa
     8401 gatccgcctt ttcataagct ttgatgattt cggcaactac agggtgccga acaacgtcac
     8461 ttgcttcaaa attaacaaaa tcgatttttt tgatttgctt taatgttcgt tctgcatgaa
     8521 caagaccact tgtcgtccca cgaggcaagt ctatctgact tgtatcccca ttgacaatca
     8581 tttttgattg ataaccgaga cgggtcaaga acattttcat ctgagcgact gtcgtgtttt
     8641 gtgcttcgtc caagataacg aatgcatcat ccaatgtccg cccccgcatg taagctaaag
     8701 gtgcgatttc gatcacgcct cgttccatca atcggttcgt atgatccaat ccaaaaattt
     8761 ggtataaagc atcataaaca ggccgcagat aaggatccac tttttctttc agatccccgg
     8821 gtagaaagcc taggttttcc cctgcctcca cagcgggccg cgtcaaaatg attttttgca
     8881 cttcgccttt ttttagggca gcaattgcta atactacggc aagaaacgtt ttccctgttc
     8941 cggctggccc tacaccaaat acgatgtcat gtttggctac cgattcaacg tatttctttt
     9001 gaccgctgtt ttttacccgt ataggttttc cattacggtc tttgacgatc tcttcctcat
     9061 acatctcaac aaaataatct aatgtacctt tttgccccat cttcaatgcc gtcacaacat
     9121 ctggcgtact tacgtggatt cctcgtttga tcaattcctg taatgtccga atgactgagg
     9181 cagccaagga aatctgggat tgctcaccaa tgatctgaat gatttctcca cgtgtatgga
     9241 tggttgtttc cgttgtttcc tcgatcagtt ttatatgctt gtcgtgtgca cctaaaagca
     9301 tgctgacatc atcagcagct gtcaatctaa tctctaaaga actagactct tccgtcaaaa
     9361 atagacatcc cctttttttc gattcattct ttcctatttt accatactca gaagaaacta
     9421 tatagcaaat aagaaaaggt tgtaaaagag tcgtttaacc atacgtacca agaaacgtta
     9481 aaaaatagcc gtttccattc gctaaaggtc tcgttttgat aaaaagaagc tgagaatgta
     9541 agttatatga aagtggagaa caaaatattc cgtttcattc agcaggtatt ctctaggtat
     9601 ttttcttgtt tcaaaaaaag aaaacaaaat agttaaaata ttcttgcatt tcaaaaaaaa
     9661 caggtgtatt attacgtcaa caaataaaca tacagcaaag cgtcgaggaa aacagtaggc
     9721 tattcaacga tttattccca gtgagtcatg taagtgagaa atgacaataa atcgaataga
     9781 cgaacatcat ttccgagtca atgtcgaaaa cgtagatcat tgtggctgcc tccattatca
     9841 ggctagcgga taactttatc aaaaagcgtc cgtgaatgaa gaagcttttt taagcgaaaa
     9901 aaggtggtac cgttctagaa tctagagccc ttttcccaag tggaaaaggg ctttttttat
     9961 attttaaggt ggtggttttc atggaatctg atattagtgg cattactaat tgctgcaacg
    10021 tttatatcgt caatcaaaat gataattatt ggaggaaaaa tttatggaag aaacaaaaac
    10081 ttattcatgg aaacaactat tgatggtcag ttcacttatc ttcgggatgt tcttcgggtc
    10141 aggtaatcta atctttcctg tccacttagg tcaaatggct ggcgcaaact gggtcagtgc
    10201 tggcgtagga tttgccatct cgggcgctct tttcccatta ctagctatct tagctgtagt
    10261 agtgacaaaa agtgatggtc tgtatgactt agctaaacct gtcggaaaat ggtatgctgc
    10321 cttgttctta atccttgttc atttgacgat cggaccattt ttcggtacac cacggacagc
    10381 tgctactgct tttgaaatgg ctgctaaacc atttttgcct gaaaaatata attcattagg
    10441 tatgttttta ttctctgctc ttttcttttt acttgcttat ttccttactg tccatcccac
    10501 acggttggtc aaatacgtcg gaaagtatct aaactccttg tttcttgcat tgttagcaat
    10561 catttttgtc gtttctttat tccacccaat gggaaatcta aatcaatctg ctgcagatac
    10621 ttaccaaaca aacgctttaa caaatggtgt cctagaaggt tataacacgg ttgatgcagt
    10681 agccttgctt gccttaagtg tcacttttgt ccatgcagtc cgtgaccttg gtttcaaaga
    10741 taaaaaagtc acagaattaa cagcaaaagc tggtagcctg agcgttgcgc tagaagtcat
    10801 gatctatttt ggtcttgttc ttctcggtgc gatgagtttg aataagatgt ctttatcaga
    10861 aaatggcgga actgcacttt ctcagatcac taatttttat ttaggtaact tcggcgctag
    10921 cttcttagga gtgatggtca cattaggtgt cttcactacc gctatgggac tcgttgtttc
    10981 ttttgcgcaa gatttccata aactgttccc taaagtcagt tatatgacat ggctgcggtt
    11041 aacgactttc gtctcttttg tcgttgcaaa tgctggttta gacaatatca tccaatggtc
    11101 tttaccagta ttgatgcttt tgtatccatt gtcgcttgcg ttgatcttgc tttccttaac
    11161 agcaaaattt ttccaaaaga caccatttgt ctatcaagta acgatgttgt ttgctgctgt
    11221 tcctgccgta ttggatatgc tggcaaattc gcctgcttta gtgagtcaac aaagagttgt
    11281 agcaagcatg ctcgaatttt atcatcatca cgttcctttt gctgcattag gacttggctg
    11341 gatggtccca acgttacttg gttacgctgg cagcctactg ttttattacg cctatcgcct
    11401 atcagggtat aaacaagaag caaatgaact accagaagaa taaccaaatc aaacacaatt
    11461 taacataaga aatattaaac aggaaaaaac cagctagatg aaagaatcct attctttcgt
    11521 ctagctattt ttttgttctc ttttttacgc gcacaaaaaa actgcggaca atgattgtcc
    11581 gcagtttaaa tgataaaatt aagattgtaa tagttctttc acaatggcat ttacttggtt
    11641 tccatctgct tttcctttga ctttaggcat gatcgcaccc atgactttgc caaattcttt
    11701 cattgatgaa gcaccagttt gtgtgattgc ttcttgaaca agttgtcgaa tttcttcgtc
    11761 ggaaagttgt tccggcatgt atttttcgac tatcacaatt tcacttttta ctttttcagc
    11821 taaatcgtca cgtcctgctt cttcaaactc atgcaaagaa tcacgtcgct gtttcatttc
    11881 gcgagacaac accgttaatt cttcttcttc tgtcaagtcg tgaccttctt taatctgctc
    11941 gttttgtata gatgacttga tcattcggat gacttgtaaa gattccttat ctttcgcttt
    12001 catcgctgtt ttcatgtcat cgtttaatct acttagtagt gacacactac caactccaat
    12061 tcatcacaga actagaattt tttgcgtttt ctagctgctt cagatttttt cttgcgtctt
    12121 acacttggtt tttcgtagaa ttcacgttta cgagattctt gtaaagtacc cgcttttgac
    12181 acggaacgtt tgaagcgacg aagagcatcg tcaagtgatt cgtttttgcg aacgactgtt
    12241 tttgacatgt taattccctc cctccgagct taaaaagtaa ccgtaattgt tattgaaata
    12301 tatctcaaaa aacaagactg tcctgtaaat attatatcta atgctgtttt gaccgtcaag
    12361 gaaatcttgc ttttttttaa aattatcaaa tgttatttta tttaaatcct tattgacaat
    12421 tttcacatct tccgaaaatc tcgaatctat gcccttcgat cgtacatcca ccgagctgtt
    12481 cttcgaaata attcattgga cacatatgga tttctttcgt tgttccgcac accgtacaga
    12541 taaagtgatg gtgatggccg atttcccctt gacagcaatg aaaacgaaac ttcatctctc
    12601 catttaaatc ggtttcttcc agtaaatcga tttctgcaaa atcatggaga tttcgataaa
    12661 tcgtatcgta acttactcct ttgaattcct gattcatata gtcaaaaact tctttagcgg
    12721 atacgtagcg attgcgcttc actaaataag ttaacaatgc ttctcttttt ttagtatatt
    12781 taaaaccgtt atttttcaat gtttctagtg attgttcaat caatgtctgt tttttcatga
    12841 cttattcctc caaatcaaaa tgattacgaa gtacacattc tagagtatgg tataataaac
    12901 ataaaaaaaa tgcaagtgag gttttatcca tgtcttccga ttctacagaa atcgttactt
    12961 tttttgtcat ctctgactct gctggagaaa ctgcgacaaa attagcgcaa gccactatgg
    13021 cccaatatcc taccgttgag ttcaatttat tccgcagaac atttgtgaca gatgagaaaa
    13081 cattgatgca ggcactgcaa gatgcactaa aagaaaaagc ccttgtcctg cacacattga
    13141 tcaatcaaga attgatcgag atgacgcgtt ctttttgtga agaacatcaa ttatttagtt
    13201 ttgatgtgat gactccgccg atatcagaaa tcgagcgctt aactggtatc aagcccattc
    13261 ggcaacctgg cgcccttcat ttattgaatg agaactattt caaacggatc aaagcaatgg
    13321 aatttgctgt aaaatacgat gacgggaaag atcctcgtgg gtttctagaa gcagatgtcg
    13381 ttttgctagg cgtatccaga acttccaaaa cgcctttgag cttgttttta gctaacaaaa
    13441 atttaaaggt tgccaatcta cctttgatcc cacaagcaca tattcccaaa cagctttggg
    13501 agatcgatcc taaaaaaatc gtgggactga cgaataaccc agatatttta aacaatatcc
    13561 gtaaagaacg gatgcgctct tacggattaa atcctgatac tgcttattcc gatatcgaaa
    13621 aaatacgagc tgaactcgat tttgcgaatg atctttatga aaaattgggc tgcgtagtaa
    13681 tcaatgtcgc ttctttatct atcgaagaaa cagcttcact tattttgaat gctttagacc
    13741 tagaagatca tagttattat ggaactgaaa ccaccgaaga aacagactaa cagtttttct
    13801 tgtctttttc ttaaaaaaac tggactgtgt cagcgaagaa gattcgttga tacagtccag
    13861 tttgtctcta tttgcaccta tcgttattga tgttccacat gtttgagcgt ctggttcaaa
    13921 atatccagta cgtgagaatc atcaagacta tacaaaatcg cttttccctc acgatgggac
    13981 ttgacgacat ggttttctct taataaacgc agttgatgcg atacagcaga ttgttccatt
    14041 tctactgctt gggtgattgc tgtcacattt tgttccccgt ctttcagata cagcagaatt
    14101 ttgagacgag tggggtcact caacattttg aatagttggc tgactttctc tacttttgtt
    14161 ttttgcgtgt ctggcaatcc attcacctcc aacttgaaaa aagactgact tctaaagttt
    14221 accacttttt ccatcagtct caagtttttt tattcttctg tcattttttt gataatcgct
    14281 tcataagcgg ctactttttc agctgcgtct tctgaagagt ttccttttac accgatataa
    14341 aatttgattt tcggctcagt tcctgaagga cggatagcga tccagccatt ttcttccagc
    14401 gtatacttca atacgtcaga tggcggtgtc gttagttttt ctacgtttcc ttcacggtct
    14461 gttctcgtca actctttgaa gtcttctgtt tggatgactt ttgctccggc aaattctgtc
    14521 ggtgcttctt cacggaattt ttccatcaaa gcagagattt ttgcagaacc ttcttgtccg
    14581 ctcattgtca cagaaatcgt tttttctgcg tagtagccat atgtttcaaa aatcgtttgc
    14641 aagccgtcat acaacgtttt gccttgtttt ttatagtaag ctgctacttc tgctaataag
    14701 agcaatgctt gaatcgcgtc tttgtcgcga acgaaaggtt taactaaata accgtaactt
    14761 tcttcgaatc cgaacataaa agtatgggaa tgatcttctt caaattgttg aattttttca
    14821 gcgatgaatt tgaatcctgt caatacattg aacatggtag ccccatagtg ttccgcaatt
    14881 gctgtaggca attcgctaga aacgattgat ttcaataccg ctgcattttc aggtaaagtg
    14941 cctcgcgatt ggtgtgcttc caaaatatat tgagcaaaca gggctccgat ttggttccct
    15001 gtcaatactt cataggagcc atttggcaaa cgaacggctg cgcctaaacg gtctgcatca
    15061 ggatctgttg caatcagtaa gtcagcgcct tctttctcgc caagtcgcat cgcatactcg
    15121 aaagcagagt gttcttctgg attcggtgat ttgactgtag tgaaatccgg gtctgcgaca
    15181 gcttgttctg gaactagtac gaattgttcg aatccagctt gtttcaacgc acgttcgccc
    15241 aacatttttc ctgttccgtg aagtggtgtg tacacaagtt tcaaatcttt acccattgtt
    15301 tccaccaatt catgatcaat cgttactgct ttgatttctt ctagataagc ggcatccact
    15361 tcttctccga tgatcgtgat caatccgcta tgttcagctt cgtcgtcaga taatacttca
    15421 acttttaacg gattgctgac ttcacggaca tatttcgtca atgcatctgc gtctgcagga
    15481 ggcatttgtc ccccatcttc tccgtagact ttatatccgt tgtaagctgc tggattgtgg
    15541 gatgcagtta ccatgattcc cgcaaacgtc ttcaaatgac ggactgcaaa agaaagctct
    15601 ggtgttggac gtaaactttc gaatacataa gaagggatat tgtgatgtgc taatgttttg
    15661 gctgcttcca tggcaaattc tggtgattga tggcgtgagt cataagcgat agcgacacct
    15721 cggcgttttg tttcttcacc ttgtgtatcc atgaaacgtg caagtccttc tgttgcttgt
    15781 cttaccgtat agatgttcat tcgattgatc ccaggtccta agattccccg catgcctgca
    15841 gtaccgaatt ccaacggtgc ataaaaagca tcttcaagtt tttcaggatc ttcacccaga
    15901 tcaattaatt gtttttttaa gttttcttct aaattttctt catgtaccca ttgttcatac
    15961 acttgttccc aagacatgaa aataacacct ctttctgaaa tatggttctt aataagtata
    16021 gcattcactt attagatatg aaagtacgag gtctaaaaaa cgcttaaatc aagaaaggat
    16081 tcttttatca agcacggttg caagtattcg cataaatcgg attcagtaga tttcacgcga
    16141 aaaaaaagag taaaagaaca attgaaaccg ttcttccact ctttttaaac ttatgcagtt
    16201 gtttcttcta aagattccaa gtatttatac acttgttgtc cagcgatccc accatcacca
    16261 acagcagtag tgatttgtcg caaatctttt tcacgaacat ctccgatggc aaaaacgcct
    16321 ggtatattcg tcttcatttc gttgtctgtt ggaatccagc cagcttcgtt cgtcaaccct
    16381 gcttctctaa atggtgcagt taatggatcc agtccaacat agatgaatac tccgtctgct
    16441 gccaaatcaa actcattgcc ggttttgaca ttacgtgctt tcacacctgt cactaccatt
    16501 tcattcccaa cgatttcgtc aacgactgta tcccacataa aggaaatttt ttcattcgca
    16561 aatgcacggt cttggatgat cttttgtgca cgtaattcat ctctacggtg gacgatgact
    16621 acttcagaag caaattgtgt caaatagatg gcttcttcta ctgctgagtc tcctcctccg
    16681 atcactacta gacgtttgtt acggaaaaac gcaccatcac aaactgcaca gtaagaaacg
    16741 ccacgtccag caaattcttc ctcgccaggt acgcctaatt tacggtggat acagcctgtt
    16801 gcgataatga ctgtttttcc ttcgtaagtt ttatcttcac aaataacttc tttgtggctg
    16861 ccgtgatcct tgatatcttg cacgattcca taagcatttt ctgtcccaaa tcttgaaaca
    16921 ccttcataca tcttataagc tagatcagga cccatgattg aatcgaaacc aggatagttt
    16981 tcgatttctg ccgtattgtt catttggccg ccaggggcgc cttgttcgat catcaatacg
    17041 gataagtttg aacgtgaagc atataaagca gcagtcatcc cagcaggacc tgcgccaata
    17101 acgattacat catacatatg tagattctcc tttacttaat caagtaagca tactttacag
    17161 ccaatgcgaa aaaaagtcta ttgttctgct tgcgtttctc gaatagcttt attatactcg
    17221 aaaaatccgc tgaaaaacaa tagactttta caaatcattg atcaatcatt cgaaagattt
    17281 tctccatttg aatcaattac ttttttatac cagttgaatg atttcttctt cgaacgggct
    17341 aatgtgccat ttccttcgtt gtcacgatcg acataaatga atccgtacct tttcttcatc
    17401 tcacctgtac cagctgatac taaatcaata catccccaag tcgtatagcc taatagatcg
    17461 actccatcta attctactgt atctttcatt gcctggatat gtgctgccag atagtcgatt
    17521 cgatagtcat cttccacata accattctca tcgggcgtat cgactgcacc taagccgttt
    17581 tctacaataa atagtggttt ttgataacga tcataaatat cattcatcgt tattctcaag
    17641 cctaatggat caatttgcca accccattca cttgcttcca gatatggatt tttgacagaa
    17701 gcaaagatat ttcctgcagt ctgttccaag agttcgttgt cagtagtcga aactcgagaa
    17761 gaataataag aaaaggagat aaaatcaaca gtatgttctt tcagcaatgc ggcatcccca
    17821 ggttccattt tgatctgaat gccatttcgt tccatttctt tcaatgcata agcgggatat
    17881 tctcctcgtg actggacatc aatgaagaaa taattttctc gatctgattt tctagaagcc
    17941 caaacatctt caggattgca agtgtatgga taatatgctc ctgctgccag catacagcct
    18001 actttgttct ccggatctac ttcatgagca atcttcgttg cgatggcact tgcaaccaac
    18061 tcatgatgtg ccgcttgata tttgatttgt tcttcatttt ctccttcttc aaaatacagc
    18121 cctgcgccca tgaatggtgc atgaaggatc atattgatct cattgaatgt caaccaatat
    18181 ttgacaagtc ctttatagcg attgaagatg actcggcaca gattttcata aaaaccaacg
    18241 agttctctag aacgccacgc accatattct ttgatcaaat gcatcggaca atcaaaatgt
    18301 gtaatcgtca caagcggctc gatcccgtac ttttgacatt ctttaaagac atcctcataa
    18361 aatttcaaac cagattcatt tggctcattt tcatcgccca ttggaaaaat acgactccaa
    18421 gcaatggaca tccgataagt cttgaacccc atttctgcaa acaaagcaat atcttcctta
    18481 taatgatgat acatatcgat cgcaattttt gctggataaa aatgatcttt atcaaattca
    18541 aacattttct tttttccagt aatgacagga aaacggtctt ctccgattgg cacaacatct
    18601 acgttcgcta acccacgtcc gccttcatca taaccaccct cgcattgatt ggctgctgta
    18661 gcaccgcccc ataaaaaatc ttttctgaat cccatcatac ttcctccatt acatgtgtat
    18721 tgcttgacaa ttctcttgcc agttcatctt ggacttcgat tccttctgct tttaaccggc
    18781 tgattgtttc cttgaattgc ggtaaatact gctgatgtgc aataaacaac tcatccatga
    18841 tccgttttgc tgtctttcct gatcgtataa gcggattgat cgtaaacgct tgtaaagctg
    18901 ttccataatc accagtcacg gctgcttcga tcgtcagcaa ttccatattc ttcattactt
    18961 gcaaccagcc tctttcagca gcaggaaggg aaccaaacgc tacatttcgt gcgccttgtg
    19021 cgccaacata ggcagtgact tctactacac aatctgccgg cagatcagga acagctccat
    19081 cattctttgt agacaccacg atctgtgttt ctttatttcc atagatcgaa gcaatcgttt
    19141 cacaggcagc atctgaataa taagcaccac ctcgtttttg caattgttca ggtttatgat
    19201 ccaattctgg atctttgtat aattcaaaca gctctgcttc tgtttctttc acttgttgcg
    19261 ctcttgtacc aatcgtttga tattcttcta aagcatgttc caacatttct tcttcacggt
    19321 agtaatagcg gtggtagcca caagggatca tgttcatttg ttttaattgt tctttgaaaa
    19381 acgggatgtc aaagatattt ttcggcaatc cattgtcttc atcgtataaa cgatcaatca
    19441 aatctgctgt gcggtcattt cctttattat ctgctacttt gtgccaatgg aagtgattta
    19501 gaccggcaaa cttgtagatc agctcttctt ttttcttgcc aagcattgct ggttctgtca
    19561 tcgtcgccat tactggcaca ttgcataatc cgatcacttt atcccatttg ccatatctga
    19621 taactgcttc tgtcaccatc ccgcttgggt tcgcgaaatt gatcagccaa gcatttggac
    19681 ataaacgctt catgtcttca acgattgcca aaaccactgg aacggtacga aaagctttga
    19741 atatcccgcc agcaccattt gtttcttgcc caatcatccc ataataacta gggatccgct
    19801 cgtctttgat tcgtgcatct aattgaccga cacgaaactg agtcgtaaca aaatccgcat
    19861 ctttcaatgc ttcttcccga tccaaagttg catagatctt gacttcatac ggagaagcat
    19921 cccacatacg ctgagacatc tgactgacga tctcaagctt ttcttttcct tcttctacat
    19981 ctacgagcca gatttctcgt atcggtaatt cctcatatct tttgataaat ccttccatca
    20041 actcgggggt gtaactgctg cctccaccaa tcgtagcgat tttgattcct tttgccatgt
    20101 tctcactcct ttgcttttta cacttttatt atcttttttg taaacaaaac aaacaataga
    20161 aattcgtttc tttccagtaa catttacaaa agttagtgtt ttctactgga tttttgtaaa
    20221 tatcttgtca aaaaatgact ttattaagct atataacata aatccgttta caaatcattt
    20281 tcaaaaaagt tataatttac gtaaaaaaac tagaagaagg tatctacatg ttattacgtg
    20341 aaaaaatcaa agaaatctcc ttttctcctt cagaaaatga agtgattcag tttctcttaa
    20401 gcgattctcc agcacttggc gaaatgacca tccaagagat tgctgagcga tgttatgtcc
    20461 acccgtccac actcatccgt gtagcaaaaa aaatgggttt tgatggctgg gtcagttttc
    20521 gtaatgcttt tttagctgaa acagcctatc ttgaagggaa ttttcaagac gtagatgcga
    20581 atcttccttt ttccaccaca gacggtatta tgacgatcgc aaataaaatg gcttctttag
    20641 aacagatgac gattcaagat acactttctc tcattcatca tgaccaactg caaaaagcca
    20701 aacaactaat gcttcaagca aaaaaaatcg tgattttcgc cagtaactcg aatactttga
    20761 tttctcaaga tttcatgctg aaaatgaagc gcatcaaaat ggatgtcacg attgtcacca
    20821 cttttggtga atcgttctat gaagcgtaca attgcacgag tgatatgtgc gggattctga
    20881 tttcttatac gggtgaaaac aatgtgatcc ttcgtaccgc agaaatattg aaacaaaatc
    20941 atgttccaat tttagcgttg accagtatcg gtgattcaac gctatcctca atgagtacag
    21001 ccgctttgcg acttacgaca cgcgaacgac tgtattcaaa aattggtaat tttacgatca
    21061 atacatcgat ttgttatctt ctagacgtgt tatatagttg tgtttttgca gaaaattatc
    21121 aacagaattt agtccatcta atttctgtag gacaaaaatt tgataaacgc cctatcagct
    21181 cagccatcat gaaagagcct ttcaattttg aaaataaaga agtggactaa aaagaatagt
    21241 taagtctatt ccattctttc acctaaccgt tcaggtcagt gcggtgataa gtgcatcgtc
    21301 tggcccgacc gtctcccctt gattttccaa aatatccaaa taatccatgt aattggtgac
    21361 gattacaggt gtttctaaac tgtatccttc cttttcgatt ttctttttgt cgaagcggag
    21421 caacagatcg ccttgtttca ctctttctcc ttgctgcacc aagctttcaa aatatttccc
    21481 ttccaactga acagtatcca atccgacatg aatcagcaat tccagacctg tttcagaaac
    21541 cattccgatt gcatgtttcg tggggaacag ggtcatgact gttccgtcaa aaggggcacg
    21601 tacttctcct ttttcagggt agatcaagat tcctcgacct agtgttcctt gtgcaaaagc
    21661 tgcatccttt gctgctttca gtggagcgat ttgtccttgt atcggtgttt ttacaatttc
    21721 tttacctgat cttttctgtc tgtcatctgt ttcacctgct tcctccttcc aaaagaaaaa
    21781 agtcagcgca aaggatacca ccatcgcaat ggcgatccca atcaatacat taatcacatc
    21841 tgttaaatca ccatctggtc taatatagtt gggaattgta aagatgccta gtccaccttg
    21901 attccaagaa gttaaattca ttaacccact atacgcgccc cctaacgcac caccgacaca
    21961 agtaaaaata aatatttttt tacgtggtaa tgtaaaccca taaatagctg gctctgtaat
    22021 ccccacaata ccagaaacaa tggctggtat tgcaattgct ttgtcttttg gatttctaag
    22081 cttaaagtag agtgcggtaa gtgctgcagt ttgtccaaaa gacactactg caacaggtgt
    22141 cataatattt tgccaaccat tcacagaaaa ttgcatcaat cccattggta cgattgccca
    22201 atggagacca aacatcacca gaatttgcca gaagaagcct acgattgctc cataaataac
    22261 tggcgaaagt gctaaaagtg tttcaaatcc agccattaaa atatcagttg cgaatgtgaa
    22321 tactggtcca acgagtaaaa aacctaaagg cattgtaata agaacggtga agaatggaac
    22381 gaagaaattc gcgatcatct caggtactaa ctttttaatt ggtttctgaa tttggctagc
    22441 taacaacaca ataaagataa tgggaatgac agaagaagcg tagttacgcg caatccaggg
    22501 aatgccgaat actgtttgat aaataggtgc ttcaaaaata gtgccagaaa atatggtcgt
    22561 tagtggtgct tctgctgcac cactcaaagc ttccagcgac aagctaggat tcattaatgc
    22621 tgcgccaagc aacatcccta cgaattcatt tactttaaat ttacgggcag ctgttaaacc
    22681 gataataaca ggcataaatt ggaatacaga atcaccgata ttatcaaaca taacaaatgt
    22741 gccagaaccg cggtcaaacg cgcctaagaa gacaaggaat gctgtcagtc cacgaatcat
    22801 cccgccagca gctaagatag caaggaatgg ttggaaacag cccgatattc catcaataag
    22861 catatcaaac ggtctcattt tttctgttga aacagcctca tcaaaagtaa ggtttcctgc
    22921 ttttataacc tcttcaaaca cgactggcac atgattcccg atgacaactt gatactgccc
    22981 tcccgctcgc attaccgtta caataccgtc catatttttc aagatctcat catttgcttt
    23041 ttcttcgttt tttaatttga aacgaagcct tgtgatacaa tgtgtcaaac cattgatatt
    23101 ttccttccca ccgacatttt ctacgatttt tctcgctaat tcttggtatt ttcccatttc
    23161 tattccctcc aatatattag tggaaggttt agccaactga atgtcactac ccttatttca
    23221 tacgttcttg ttaatttatc ctcctttttt tatttattta caacgattct catgcactaa
    23281 acgcgcagta tggatcgtta aatacatttt ttcgtccgtg gacatctggt agttgaacgt
    23341 ctcggctaaa aagtctgcta ttttctcaac gcaaccaaac gtatccttat attttttttg
    23401 aataacctga aacaattcct cagaaacttc tcccacttct gatttttctc catctaggac
    23461 gcgtgtcaga aaaaaacgta agtgtgtgac gaatcgaaaa aaatggactg aatcttcatc
    23521 aaatgtaatc ttatagtaat agcggacgat atttagaata tcctgtattg ttatagtaaa
    23581 caggtaggta ttgttttgtt ggctttgaat gccttgtgca ttgactaaat gcaatgcgat
    23641 aaatccggct tcatcttctg ataacttgat gtggtattta tccgagattt tcttcactgt
    23701 ttttttcccg atggcatact ctttaggaaa tagttgtttg atatcataca gcaatacatt
    23761 tggtacaaat attcccattt tgtgacgttc gatagccgta tacaaatgat ccgtcaatgc
    23821 aatatacaca gaatcattca actggacttg tagagcctct tttgtatatt caatgatttc
    23881 acaagaaatt tctaagtact caagaggaat cgcttgtgcc aattcttgga actgttgtga
    23941 aagcccgtca tttgtcaact gaaatttttt gtcgatgcat gagtcaaaaa tcgggtcacc
    24001 cactttcttt ttgaatgcca aaccttttcc catcacgatc atttcctgat ttctttcatc
    24061 cctggttatt acgacgttgt tattcagtac tttctcaatc agcatgtttt gctcctttcc
    24121 atgatatata gggctgtatt caaaacaaaa agaaaaaccc aaaaagccgt ccatggaacc
    24181 atgggagact catcaggttt agcttgcatc aggcaatcac tatccaagtt gtatcgtttt
    24241 ctttatatta tcgaaagcaa acgctttctt agtggctatt aggcactttt gactagctgt
    24301 cgtcgtcttt tttaaatcgg gtgactacgc cactaacgct cacagatgaa gaatctggga
    24361 agctctgttt tattttcact ctagcgctta ggacaaaatg ctactatgct actgtcacaa
    24421 cctcttttta cacaccactg ctttgcagtt tgtacatatc tgcatacaaa ccattttgcg
    24481 ctagaagtgt ttcatgattc ccacgctcta ctatatgacc tttgtctaaa actaaaatca
    24541 attctgcatc ccgaatcgtg gacagccgat gggcaatcgc aatcgttgtc cgtccttgtc
    24601 gcatttttgc caatccttct tggatcaatc cttcggtttc agtatcgata tttgctgttg
    24661 cttcatccaa tactagtatt ttaggatctg tcacgattgt tcgcgcaaaa gtgatcagct
    24721 gtcgttgtcc actagaatag ctggcaccgt gttcgatcac ttttgagtga tatccttttg
    24781 gtaattcatc gatgaacttg tttgcttgaa caaactcagc tgcatggcga atctgttcgt
    24841 ctgtgatagc tggattcatc atccggatat ttcctgcaat atctccataa aacaagaagg
    24901 catcttgcaa gaccaatccc attttcttac gtaactcttc cattggatat tctcgaatgt
    24961 catgatcatc aatcaagatt tggccttcat aaaattcgta aaaccgcatc aatacgttga
    25021 tgatcgagct ttttccgctt ccggtgtgcc ccactaatgc aacggtctca cccggattag
    25081 cgacaaaaga gatattgttc aatacattgt gctctccatc ataagaaaag cttacattgc
    25141 gaaactcgat cttacctgaa gtaatcgctt gatctgctcc aggattttgt tgcggtgcat
    25201 attcttctgt atccatgatt ttcaaaatac gactaccggc aaccatccca tctgtaaagg
    25261 tgctcaaaaa gtccatcatt tgagacattg gattaaaaaa tccctggaca taggtcgtaa
    25321 atgcatagat cagtccaact tctacgggag aatgcaacgc atcgatccca aacaaagtca
    25381 acgccaacgc aatcgccaat gcatagagaa aattgatgat cggacttaac agaatcgaat
    25441 tcgttttgat catcgcatag cgcgtgtcta aatactcgtt gttcacttgt tcaaattctt
    25501 tagctaaacg agcttcttgg cgaaactgct ggataatacg catgccggaa atcgattcat
    25561 tcaatttcgt gttcagctga cttaattttt cccgcatatt tcggtaaata cgagaactga
    25621 atttctggta ataccagatg acgattccta aaatcggcaa gaacaccaaa gtccacaagg
    25681 caatttctcc attgatttga aacatggcaa cgaaagaaga aacgactgca aagatcccag
    25741 tcaataccat caaaaagaca taccaaaatt caaatagcgt ttctgtgtca ttcgtcactc
    25801 gagaaacggt cgatcctgcc ggtgtctggt caaaataacg catacctagt gtatgcagct
    25861 tttcaaataa tcttacccga acatactgat aggtcttcaa tgaagccatg gaatacaaat
    25921 accattggaa aaaccaaatg atacttttga ctatgactcc aaacaagtac acaccagcaa
    25981 aaaacaaaat aacttgtgtc gtagctgact gtttagccag atgatcatcc ataaaagttt
    26041 ggatgatcct tggcaatagg acattgatca cagacagggc aaacgcaaat aagatagcaa
    26101 cgatgaacgt tcttctaaaa ggtttggcga acttcatcag tcgtttgatg atcttcttct
    26161 gttctttaag tggaatcgat tttgtccatt ccgattgata attttcatcc atcaggcctc
    26221 gcctccttct atcttcgctt ctaattgctg tttttcccac attcgttcat accagccacc
    26281 taatgcaagc agctcgtggt gggttcctcg ttcaatgatt ttcccttgat cgacaacaat
    26341 gatttctttt gcatgcatca cgctgcttaa acggtgagct gcaatgatgg ttgttttctc
    26401 ttttcttatt tcttttaaat tatgcaagat agcttcttct gttttggcat ctactgcaga
    26461 aagtgcatca tctaagatca gcaattcagg atttttgatc aatgctcgag caatcgaaat
    26521 cctttgtttc tgtccgccag ataaagagac tccacgttct ccaactaagg tatcataacc
    26581 ttttggcaat tccttgattt cattgttgat aaatgctaaa gaagccgcat gctctacttc
    26641 ttcttctgaa agttttggat tagaaaaacg gatattatct cgaatggtca tcgaaaacag
    26701 gaagtgatcc tgaggcacat aaccgattga tcctaataaa gcattcaatg aatattcttt
    26761 gatcgaacgt ccgccaaatt ggattttccc ttgataatca tcgtattcac gcatcagtaa
    26821 tttgatgatt gtcgtttttc ccgcaccagt tttcccaaca atacctaatg tttctccttc
    26881 ttggatcgca aatttgattt gttctaatgc tggtgattct tctttcggat agttaaaaga
    26941 ggaaatagct acattcagct cgccttttgc cggggtctgc actgcaccca gttgttccac
    27001 gatatgcgtc ttttcatgca aaagttcatt aacgcgatca taagaagcat ttcctctttc
    27061 caatacgttg aacaatcggc caatcgcaaa catcggccaa acaagcatac cgatataact
    27121 aataaatgag accatctgcc caatcgagat cgtgccttcc aagacatact ttccacctaa
    27181 aataattgtt gcaacataag acagaccgat aatcaaggta atgaatggat caaataagga
    27241 gtctaaaaaa ttgactcgtt tgtttttaat aattgcatct tcaatctttt cttcaaaatc
    27301 cgcgagatct tctttttctt gtccaaatgt tttaatgact ttgatcccag tgatactttc
    27361 ttgtgtctta tcattgatac tagaaaaagc ttcttgcgaa tcacgaaaag catcgtggag
    27421 ttttgacccc agcactcgtg aagtaacggc tagcaaaggc agaggaatca gcgcaatcag
    27481 tgttaagcgc caatcaataa acaaaatcat cgcaatgatc gttgttccgc ccgtaatcac
    27541 tgaatctgca aaggtcaaga ttccagctcc tgctacattc tggattgcat tcaaatcatt
    27601 cgttgcatga gccatcaaat ctccagtccg atatttttgg taaaagagat tgtccatttc
    27661 tgtaaaatgt ttgaatagct gctgccgaag ttctttctcc aaccgagctg cacttcccca
    27721 aatattcgtc cgccagatat aacgaaaaag atattgtaag aaagctgcaa ggatcaatag
    27781 taagatccac caagaaatga tctttattga taaattctta tcggcgatct catcaatgat
    27841 gatcccaatc acttttggag gaactaactg taccaaggcc actgcgaata gggagaaaat
    27901 cccaattaaa taatgtttct tttcctgacg aaaaaaccaa cctaattttc taaaaatcga
    27961 cattttactc ctcctttgtc tttatcaaga gcataggatt gtctgtcctt gtcttttttg
    28021 ctgaatagtc tgaatagtct aacaaattac gaaataaaaa acggactgaa aaaatcagcc
    28081 cgcaaaaagt ctttgggtca gaacctattt tttcccttgg ttcttcattt gctgcatcat
    28141 ctggcgaatt ttcttctcag atggtttttg ccccattgac atcatcattg atcgcaacat
    28201 gtcctcatta acgggaggat ttttttctaa atagtctttc atatatttac gcgctaggaa
    28261 aaagccacct actgcgccga ttagcaaagc aataatagca ataagtacga caatacctgt
    28321 tgataccata taaatctctc ctttctattt ccgaattgct ctcaatgatt tattttacta
    28381 aagtttattg aaaaaagaaa ggcgtattct ttagtttcat gcaaaaaata gtggtttttt
    28441 tagagaagaa caaaatttct ttcattaacc agcaagacac gccacgaaaa aaaattaggc
    28501 ataccgaatc tttttcttta attttttctt tctgaggtgt agaatgtaat cgtagataaa
    28561 taggaaaggt ggttttttct tgaataatca atccaacaaa caatttcata agcatcgact
    28621 tattgaacat acaaatggtt tatctttagc tgaagtaaat ggaacagtgg atgtaccaaa
    28681 gggaaaaagt ttttttaaaa cacttcttgc ttactctgga ccaggtgcat tagtagcagt
    28741 tggttatatg gatccaggta actggtccac ttcgatcact ggtggacaaa atttccaata
    28801 tttattgatg tcagttattt tgatgtctag tctaattgct atgcttttac agtatatggc
    28861 agcaaaatta ggaatcgtga cccaaatgga tttggcccaa gcaatccgag cacggacaag
    28921 taagacattg ggtgtcattt tatggatctt gactgaatta gccattatgg caacagacat
    28981 cgcagaagtc attggtgcag caatcgccct ctacttactt tttgatattc cattggtaat
    29041 tgccgtattt atcactgtgt tagatgtttt cgtcctttta ttgctgacaa aagtcgggtt
    29101 tcgtaaaatc gaagctttgg ttgtctgctt gattttcgtc attttattcg ttttcgtcta
    29161 tcaagttggc ttgtctaacc ctgattggca cagtttattt gctggcttta tccctaacag
    29221 tcatacattc tcagactcac ctgtcatagg tggtgaaact ccgctgactg gagcgttagg
    29281 gattattggt gcaacagtca tgccgcataa cttatatctt cattcagcag tttctcaaac
    29341 tcggaagatc gatcaccaag acgaagaaga tgtagcacaa gcggtacgct tttctacttg
    29401 ggactctaat atccagttgt caatggcttt tttagtcaat gcactgctat tgatcatggg
    29461 tgtcgctgta ttcaaaaccg gttctgtcca agatccttcc ttttttggtc tgtatgaagc
    29521 tttatctgat ccatcagcta tgagcaatgg tatcttgatt gctgtagcaa aatctggtat
    29581 cttgtctact ttatttgctg tagcacttct tgcttctggc cagaactcta ctattactgg
    29641 tacgttgacc ggtcaagtca tcatggaagg attcatccat atgcgtatcc cgatttggct
    29701 aagaagacta gtcacacgat tgctttctgt gattcctgta ttgatttgtg ttttgtttac
    29761 aagtacaaaa ggaacgatcg aagaacatac cgctttgaat aacttgatga atgaatccca
    29821 agtttttctg gcttttgcat tgccattctc gatgattcct ttactgatga tgaccaatag
    29881 ccaagcggag atggggagcc gattcaaaaa ttcatttgtt gtaaaacttc ttggctggtt
    29941 ctctgtgatt agtctgactt acttgaactt acgaggatta ccaggtcaaa tcgaaagttt
    30001 cttcggcgag caagccacct cagctcaact agcattggct gatcaaatcg cctatgtaat
    30061 cattgttctt gtccttctcc tgttggcatg gacgattggt gatttatata aaggaaacaa
    30121 aaaatatgaa cagcgtttgc aagaaacgat agaagaaatc gaatagaaac tgattctttt
    30181 acacaaagga ggttgtgaca gaagtgggca gcttcaagaa ataagaagga atttaagaaa
    30241 attgcttttc aaatttttgt gaaatttcgg cttatttccg aagaagttac ttctggaaca
    30301 ccgtgtatca gaggttgtga aaaagctgcc ctgcatcaag taataagaac agccaaacaa
    30361 aaatagttcc tcatatttta cgtttggttg agcttattac cgcagatgca agcttttgag
    30421 caccgtttat tcggaaaaag gaactgcgac aagacttttg tcacagttcc ctttttattt
    30481 ggaagataaa gcttttttca gattcaattt actaaaaact agcatgcttg ttactgcgat
    30541 gaattgcgtt aatggcacgc ctgcgccagt gtagacactt aaaaaataat cctttttttc
    30601 tggcgcataa gaacaaaacc acgagacacc gaaaagaaaa accaattgtg tcagtattaa
    30661 tccgatgact acaatcaaag aggaactata ataggcacga tcagcttttg caaatacggt
    30721 tcctagtatc ataagtaata tccctgctat tgaagcaatc agcacgggaa tggccagaac
    30781 ttggtaaatt tttatcatga cattcgcgac ttttgctgtt tttgtcaact ggaaatcagg
    30841 tgttctcgga tcactgctat cgatccaatt atccattagt ggaagattca ataattcttg
    30901 tgcctgttcg acttgttctt gcgtcccaaa actataattc cccccttgat ggaaatcttt
    30961 gtatcgccat gcataagcat atcctgattt cagaaaatca aatacgattg gcagatcatt
    31021 catcgtcttt ccatcccctg atcccatcag atagaattct tttttctttt tgatagttcc
    31081 cttttgatag gcttcttcta attcttgatt gacttttttc caaaaatcat tggtttcttt
    31141 tgcattgttt tggtaataac cagattcgct taccacatct cgcaatgccc aaaaaatgat
    31201 atctcctggt aattctttta cttttccgcc ttgggtccac gcatgagtcg tatacaattc
    31261 gtcaatacga gtagaaacag tatgaaatgt aggagatgcg tctaaagctt tatttaatgc
    31321 agcatgcgag acccatatct cactgttttc tttatttaag tttgtttcgt catctattcg
    31381 gatcagctgt ttcatcaaac gtccaaattc gccactcgaa cggtcattga tggctgcaat
    31441 accatatgtt gtctcgtttt tatattcgat ccactgatag acgatggaga aaccgactag
    31501 agggagtaaa aacaatgaaa gtttcagcca ttcttgtttc gaaaggagaa atggtcgttc
    31561 ttttaacttc tttgcttctt tgaaagaaaa gtcttgtcct agcaagatct gaacgaaact
    31621 gatgcctaac gcgactacag taaaaggaag aagccagatg gaatcttcgc gaatgaacca
    31681 aaagaaagga aaagaaacag ctagccctaa aaaccacggc agcaattttt tgctggaatt
    31741 atatttgcgg taataaatag ctagtaaaca agcgataatg atctcaacag tcgggatcac
    31801 gagagcatta cgatatgttc gagtggaata ttcatgtgta aaactaatcg gagaaaacaa
    31861 aaaataaaaa tagatactta aaagaagata cttgttcttc acgattggtt taaacgctag
    31921 tgcaaccaat atactggcaa gaatactgaa catgccgaat aaaactgcat aagaaagatg
    31981 cagtttatgt gcaagtacta aaaacaagct gtaggaaatc ccttttgaaa gtgtcgtagt
    32041 cgtgtactcc cctagccatt taccatccaa aatattttga gcatagtgaa tcagcagctg
    32101 atcatcatag gtcgccgaca tatctgttcc atagattgct ttactatata aatacaaccg
    32161 aataattgta aataatacgg ctatgccaag aataaagtat gtatgtttct tttttagttg
    32221 gtcgatcaag gggtttaaaa tgttcagcat cttttcgtcc tttcaatcac gttttgctac
    32281 ttgtttgtga aacttttcgt tttttacttt tctatcagta taccctgttt gtctgaattt
    32341 aaaaagaggg ggcaaaagga gcatggcgaa aacgaatgca aaaagcactc ctttgtttct
    32401 taaacaaaaa aggacaaggc agactgccca atcctttttt gttgctgtca ggtagaaaac
    32461 ttaaagtgtg acttcttctg ctaataactc agggaacact tcgggatcga atgcttgcgc
    32521 tttgaacatg gaaatttctt ttccatatgg tgcgtaagct ttctttttat ctttaccgac
    32581 atatggggtt tctaatattt tcgaaatgtt gtcaaacatt ggatcatgga cgattttgtt
    32641 caatgtgtca aatccaattg ttccaaaacc gatattggca tgccgatctt tatgagaacc
    32701 ttgaggattt ttagaatcat tgatatgcag tactttaagc cgatctaatc cgatgacctt
    32761 atcaaactct tccattacac ctgaaaaatc ttcttttata ttatatccgg catcattcgt
    32821 atgacatgta tcaaaagtaa cggataattt ttcattcaat tttactccat cgatgatttg
    32881 cgctaattcc tcaaatgttc gaccgatttc cgtacctttc cctgccatcg tctccaaagc
    32941 gatctgtgcc gtctgttctt ttgtcaaaac ttcattcaac ccctcaataa ttctagcaat
    33001 cccagcttct gcccctgctc ctacatgagc gcctgggtga agggtgattt gagtagcacc
    33061 taaagcttcc gcacggacaa tctcttctct cagaaattgt acagcaaatg gaaacatttc
    33121 tggtttgatc gtatttccca aattaatgat ataaggcgca tgaacgacga tatttgttag
    33181 tccgttttct gccataaatg cttttccggc atcaatattc atctcttcga tagcttttct
    33241 tctagtattt tgaggagcgc ctgtatagat cataaaggtc gaagatccgt aactggctgc
    33301 ttcttctgcc gcgcctaaca gcattttctt tccgctcatg ctgacgtgtg agcctaataa
    33361 catggatgga ttcctccttg aaaggcaatt gtttcgaaca attcctgtat attgataaga
    33421 tgatgtacaa agaaaatagt ttgtttttct ttgccctgtt ctccatagta actgaaactt
    33481 tccctaaaga aaagcttaag aactctttca taaaaaagat catttcctca cgttttatct
    33541 cattcgaaaa agaaattcct gtcaaaaaca gccttgtctg tttttttgtc ctattatttg
    33601 ctataattag cgaaataaaa ccattagttg aggtgaccct tttgccacgc aaaaatactc
    33661 gaaaaaaaca gaatagaaga aaaaaagaaa aatggtttgt tcctaagatt atttttagag
    33721 tgtttcaatc attgactgtt tttattactg ttcttctttt gttgttcgca gctctaggta
    33781 tcggaatagg tgctggctac tttgcctatc ttgtcgaaga cacacaattg ccgactaaaa
    33841 aagaactgca gacagaacta ggaaacatta cggaaacgtc aaagattgtt tatgcagata
    33901 atacagagat atcaaaaatc cagacagatc tgatgcggac gactatttca tctgataaga
    33961 tttcgccttt attgaaaacc gcgattatca gtacagaaga tgaatacttc gataaacacc
    34021 aaggttatgt ccctaaagct gttttacgag cactagtttc agaagcgact ggcatcggct
    34081 cgtctggagg atccactttg acacagcaat tagtcaaaca acagatccta accgatgaaa
    34141 caacattcaa acgtaaagca aacgagatcg ttctttctgc acaagtagaa aaacactttt
    34201 caaaagatga gatcattact acgtatttga atgtctcacc atttggtcgg aataataagg
    34261 ggcaaaatat tgctggagtc caggaagctg ctagaggaat ctttggtgta gatgcaaagg
    34321 atgtgactct gccgcaagct gcttatatcg ctggtttgcc tcaaagccct atcacgtata
    34381 gtccatacac gaatacaggc gcgctaaaag aagatctttc tgccggtctt gccagaaaag
    34441 attttgtttt attcagtatg taccgtgaag gacaaattac gaaagaacaa tacgaagaag
    34501 cgaaagccta tgatcttaca aaagactttc tcccacaaca aatcgcggaa cagactgaca
    34561 gagaattctt gtattatacc gtgatgaacg aagcaacaag gattattgca caacaattgg
    34621 cagaaaaaga taatgctgat atgtcagatt catcggtcag tgaagcttat tatcaaaaag
    34681 cacagcaaac gatccaaaac aaaggatata cgatccattc gacgattgat aaagatatct
    34741 atgctgcatt gcaaaccggc gtagaaaatt atggctacat gttagatgat ggtgctggta
    34801 gccaagtgga gactggaaat gtattgatgg ataacagaac cggacgtatc tatggcttcg
    34861 tgggtggtcg gaattacagc cagaatcaaa ataaccacgc ctttgataca gaacgtcaag
    34921 ctggttcatc catcaaaccg gttcttgttt acggtcctgc aatcgatatg ggacttgtcg
    34981 gatcagaatc ccgtgtatca gattatgcaa cgacttggca agaaggaaaa aatgctggtg
    35041 agaaaatcgt caatgcgacc aatgaagggt cgaacacctt ccaaaccgtc cgtgagtcac
    35101 tggaatggtc caacaatatc ccagcttatc acttatatca agatgtgttg aattccggtg
    35161 gatcgaaaca atacgcttac gagcactact tggcgaagat gaactaccca gcaaatgata
    35221 attggggcgt tgaatcggct cctttaggga cagtagatgt aacgacgctt caacagacaa
    35281 atggattcca ggccttagca aatggtggag tctacgaaga aggctatatc attgattcca
    35341 tcacagataa tgcaggtaat gtgatttata aacatgaaag taattctgtc cgtatttatt
    35401 ccgaagcaac ggcatcgatc atgaatgaca tgatgcgtag tgtgatcaat gaaaaaatca
    35461 ctacaccatt caaagatgtc atctcaagct taaacggaaa tctaggaaat gcagattggg
    35521 tcggaaaaac tggttctacc aatgaatacc gagattcatg gctgatcgtc tcaactccat
    35581 ctatcactat cagtagttgg gcaggacacg atgacaatac tggaatggac agccaagcaa
    35641 gaatacgttc ggctaattat cttgccaatc taatcaatca agcttaccaa gcaaaccctg
    35701 agattttcgg cactgatgag aaatttgact tatcatccga tgtgatgaag aaaaaagtat
    35761 ctgggttcac aggacaaaca gctggaaaag ttactgtcaa taaaaaatct atccaaacgc
    35821 caggaaaaac agtggaatca ctttgggcaa aaaatggtcc gaagaaaagc gcctttaaat
    35881 tcggcgttgg cggtactgat gaaaactata cagattactg gaacaccgct tcagcttatg
    35941 ctagagcgaa tccagagacc aaagaatcag acgataaaga tgattgatct aatagattaa
    36001 tcagaattaa agggagctgc gacaaaaatc ttgtcacagc tccctttttc cgaataaatg
    36061 gtgttcaaaa gcttacatct acgatattaa gacaaattta tgtaaaaatg tgaaaaacca
    36121 ttttcacaaa atttttctat ataactttac taacgaaact gttttaattt cttttcttgt
    36181 ctttggaata attcggttag tttttctgca aattgccctt ttactgattc ttttaagtgt
    36241 gcatgtcggt tagaaaattc ttgagtagct tcttctgcag tcatttggtg gttttgatct
    36301 gtcaatcgtt tttctgccca agtttgctga gatatcccca taccaactga acgtacattt
    36361 gatcgatgta gatttttctc taattctttt agtaattgca ttaaaaattc attcataaga
    36421 tgatttctcc atagttattt gtctgatttt ttgacgatag gaacgttcta gttcgtcttg
    36481 ctgctgatag agttttcgtc gttctacttg tagggcttgt tgataatgct cctgataatt
    36541 cgaataactt cgtcttgctt gaaacagagg ctcattatct aaagctaagt tctttaatac
    36601 atgatgcagt cgctgctcct cttgctccat caatcgtaat ccttgattct taaagtggat
    36661 caattcatct tcttgagctt ctaattgtct tcgttcactt cgataatctc tttccaattc
    36721 ttctagtttc atctacttct cctttaattg aattgctgtg ctaattctcg atctcgtgcc
    36781 acgatttcat tgattttgtc ttggatctcc ttcgccaatg tatcaaaggc ctcccccata
    36841 cgtcttgcct tattgattcg tagcagatag acttctttcg cagaatcgac taagttctct
    36901 tttgtggcgc ccacactagc taatgcttct atgatttcct gttcagtcaa cgaaggggcg
    36961 acaacacgtg cttgccgcaa gccttcttgc cattttttct ctagctcaaa aattcctctt
    37021 tggttgatgc ggataacttc ttccatagcg cttttcattt ttaccgataa cttttccacc
    37081 actaacctag cttgtgtgtc atctaagtaa atttgttcat taactgtcag ccggccgcca
    37141 cttaatcgta gttttttacg tatgttgttc agttcttgca actgatagga aaacaactgg
    37201 gtcgcttggt tttctttctg ttgttttcga gctttaacat tgttttcatt ttcaggaata
    37261 atcagctttc cattttcatc aaacttccaa gaggttaaac tgtgggaagc aagcagattc
    37321 aagtatgctg tttccatact gatccgaact tcagcacctg tgccattacc accaaaatta
    37381 ccgataaaat cggcgtgatt tcggtaattg gtgagcatac cgggattttc ttccacccat
    37441 ttttttgctt ctggtgataa gagatcatac gggtccggcc cgttgaagcc gacatttttc
    37501 cattgtttct ctgctgctac atataatgct aagaatccac ctaatgaatg gccggtagta
    37561 gaaatagcag cttctccata ttcctttttt acttcattag caaatgcaat cgctgaattg
    37621 atttgccccg ctgttttcaa tccactaacg gataaaatct tgtttgttgt tgctttttca
    37681 gaaaaacttg ctcctggtct attcccatag agattcataa cacttcttgc atccgtttcc
    37741 aaatctttcc aatcgcttaa gttcgttcct gcaaaagcaa tcactacttg agaaatatcc
    37801 actttaccgt tcttgattgg cgctacagcc atcgcctgca tgccgtcgaa ggagtttttg
    37861 atttttagga tttggaattt tgtttctcca aagtttttaa tggcgccttc tttgtaactt
    37921 ttactatatt gaggatgttt tggatctagc caatatactt tattacttat tcctttatac
    37981 tgcttatcag taattgtcat actttttcct cactcccatc tgtatagata actataatct
    38041 catcaaccgt aatcccttct ttttgtactt cttcattttc aacaccatag ccatctatct
    38101 cattgctttc ttttgtaaag ctataatcaa aataaacggc ttttccttct gtattggtca
    38161 tcgttatcaa tgcttcatag attcctgtca tgtcgttttt ctcaaattgt tcgattttca
    38221 cttctttgat atccgcaaag gtatttttca gaactttgac ggactgtttt tctactgcga
    38281 gtaaatcttg ctgtttttgc gcttctcttt tgtccatgta aaattttcct ccgattccta
    38341 tagtaagaat ggtcaaaatg atgactatgg tctttcgtct tttcttaggc aaatagaagt
    38401 ctcctttcgg gttatgtatg atggattgtt tctcctttaa gataagtacg caatcgagcc
    38461 tggatttttt tggatttttt agagttactt ttctactttt ctactttctt ttttatcacg
    38521 ttttcatttt aaagtaattt tgatagtagt gaacaaaatg tagcatctac gcacagattg
    38581 tgtcgtatac gatggacgta aggtttgttt ccgccattct ctcttttttt taaagtcaca
    38641 aaaaaagggg ttatgacaaa attttgtcat aacccctttt ctcgtataaa ggttgttcca
    38701 gaagttgacc actttgggaa caacctttaa atgattgatc ttttattatt tagttgatcc
    38761 tttttcttcg attccataag gcaagataat cgttttttct tcgacttctt ctttattcat
    38821 cattttcgtc aataggcgca tggataccgc tcctaaatcg tataatggtt gtgtgatact
    38881 tgtcaaacga ggacgagcta cttctgtcag taaagaattg ttgcttgtga tgatttcgaa
    38941 ttcttctggt acttttacgc cgcggtctaa taaaccatcc aagataccaa tggctaattc
    39001 atcgtctgaa acatagacag ctgttgcacc gctattatgg atccggtcaa ctagagacag
    39061 accatcttta aagttgtatt gtgcctcaaa aatcaatcct tcgctatatg gtagattgtt
    39121 ttcgcttaat gcttctttat agccttttag acggttttga ccattgatag gatcaatcag
    39181 cgcaccgctg acaaaagcga tttttttatt gccgcttttt gctaatttat ttactgcatc
    39241 ttttgttgct gatacataat caatgtttac gctacctact tgttcatctg gatcaatgga
    39301 accagctagt acaacaggcg tttttgaacg tgaaaattct ccacggattt cgtctgtgat
    39361 atggtgaccc ataaagatca cgccgtccac ttgcttagcc aataaattat tcaatacatt
    39421 gacttctttt tgatcgttgc catctgagtt tgctaagatg atattgtatt tgtacattgt
    39481 tgccacatcg tcgataccac gtgctaaaga ggcaaagaac atattgctga catcaggaat
    39541 gattacccca actgttgttg ttttcttact tgccaagcca cgtgcgactg catttggacg
    39601 ataatccaag cgatcgataa cttccaagac tttttttctt gttgctggtt tgacgtttgg
    39661 attgccattt acgacacgtg aaacagtagc catcgaaaca tttgcctctc tcgctacatc
    39721 atagatagtg attgtttgct tttccatttg tgttctccta ttcatatttt atatgttttc
    39781 tgaaaatacg tcttacattt ctaaaatagg atatcaaata atctcaacaa ttgcaaccgt
    39841 tttatctctg ttttcatgaa aatttttact tttttcagtt ttaagaacgt tggtctttta
    39901 atcaatcagt ggtacaatta ttgaatacaa aattaattta gaaagtaggt tgccaaatga
    39961 ataacgtaaa aatcaatgaa ctacgtcaat ggatggcaca acaccaatta gaattggctt
    40021 atatcagcga ccctggccac atcgcttact tttccggata tgaaagtgat cctcacgagc
    40081 gtgtactagc tctttttatc cctctggaac aagatccttt ccttttcact cctgctctgg
    40141 aagttgaaga tgctcaaaac agcagctggg cgtacgatgt acgtggctac ttagacagcg
    40201 aaaatccttg ggagatcatc ggaaaagagc ttcgcgcacg ctatgggcaa cctggtaatg
    40261 taggtattga aaagaatgct ctgactgtcg atcgcttcga tgctatctct gatatcttga
    40321 caggtacaga ttcttacacc gatctaactt ctattatcca gcgtctgcaa ctgatcaaaa
    40381 cggtagaaga aaaagacaaa ctgatcgaag ctggtaaatg ggccgatgtt gcctttgaaa
    40441 ttggcttcaa aacagtaaaa gaaggcgtaa ctgaacaagc aattatcgca gaaatcgaat
    40501 accaattaaa aaaacaaggt gtttcacaaa tgtctttcga cacattagtc cttgcaggag
    40561 caaatgctgc aagccctcat ggtacaccag gaagcacgaa ggtttcacca aatgaactag
    40621 tgttattcga tcttggcgtt atttggaatg gctattgcag tgatgctact cgtacagttg
    40681 cttatcaaaa accaactgaa ttccaagaaa aaatctataa catcactctt gaagcacagc
    40741 ttgccgcaca agaggcagtt cgcccaggtg tgacagcagg tgaacttgat caaatcgcac
    40801 gaaacgtgat caacagctat ggctacggcg aatatttcaa tcaccgttta ggtcacggaa
    40861 tcggaacaac cgtccacgaa ttcccttctc ttgtagaagg aaacgactta gtgattgaag
    40921 aagggatgtg cttctctctt gaaccaggaa tctatattcc tgaaaaagta ggggtacgta
    40981 tcgaagattg tgtgtatgtg acaagtgatg gttgtgtgcc attcacgact acaccaaaag
    41041 aattacttgt tttagagtaa tgaaaataaa aaaggtgaga gctggtccgc tctcaccttt
    41101 tttattctag aaatgagtaa tcttagtgat tggtagtcga atctgtcatt gtatctttca
    41161 tttctttttt agcttctttt gcatcttctt ttgcatcttc ttttgccatt ttcaacattt
    41221 cttttgtgtc atctgcaact ggttttgctt ctgacattcc ttcattgacc gtctctcctg
    41281 ctttatctgc agcatctttt acatcgatca tgatatcttc tgaagtatct ttagcaatac
    41341 tacctaattc gtctgctggc tttttcagat cttctgctgt ttttttgaaa cgattagata
    41401 aatcagctga ttgttctttg aggtttaaca agatatcatc tgattcgctt cctgcttcct
    41461 ctgctgattc acttaccttc tgcttaacat tgcctgctag atcccctgct tgttgagaaa
    41521 gatcttgcgc tttttctttt gcaatacctg ttaactcaga tgatttttct tttgccatat
    41581 ctgtgtaatc tgaagccatg tccatcaaat catctgcttg agcagccaat tcatcccgaa
    41641 gttctttacc agatttgggt gctaacaata atgcggcgat tgctgcggct gtacctccaa
    41701 ctactgcacc taataaaaat ccaccttttt tagccattct tattttcctc ctgtcgtttc
    41761 agtatgtttt ttgtttttaa aaatttcatc gctgttccac cgacttttcc ggcaacagtc
    41821 gctttagctg tcgtttttcc gattccgccg actttcgtca cgatgttttt actagaatga
    41881 ttaagttccg atacactttc acttaaatca gcaactgctg tgaacaatgg atcgatcgtt
    41941 gcgacttttc cattgatatc caagagcagc tcattacttt tgactagcaa gccttctact
    42001 tgtctagata aaagatctac gtcttgtgtg acgatctcaa ttgtcgtatt tgcttctgcg
    42061 acagtctggt ctactttttc taaagttttg gaaacttgca acaatacgcg aacgatgaaa
    42121 acgacaagta tcgcaaaggc gattgctgcg atcaatcctg caatttctcc tcctgacatg
    42181 atcaaactcc cttcttgtct ctcttttcta taaggatagc attttcgtgt tttttaaaca
    42241 aataaaaacg agcttcaact actttttatt caattagcag ctgaagctcg ttagaaaaaa
    42301 agattatttt ttcttttctt ctttgatttc tgttattcct tttggattat gattgatctt
    42361 gcttccttct gcttctaatg ttttacctaa agacatgatg tattcacgca aaggtgcccc
    42421 tacttctgga tgtgtcagac catattcaat acttgttttc ataaaaccaa atttgtcacc
    42481 aacgtcataa cgtttacctg tgaatttacg ggcaaatacg cgttgtgttt tattcaacgt
    42541 atcgattgcg tcagttagtt ggatctcatt tccagcgcct ggttgttgtt ctgataatac
    42601 atcaaagatt tctggagtca ataagtaacg cccaataata gctaaatcac ttggtgcttt
    42661 gcttggatct ggtttttcaa caaagttttt gacattgtat aacccatctt ccagtacttc
    42721 ccctgggttg atgattccgt attttgaagt ttcatcgtga ggaacttgca taacggcaat
    42781 cgtagaagcg tgtgtacgct catagtcatc gatcaattgc tgtgtcaatg gtacttcgtc
    42841 ttccatgata tcatcgccta gcataacgac aaacggttca tttccaataa aggctcttgc
    42901 ttgaagaacg gcgtgtccta acccctttgg atgagattga cggatgaaat gcaaattgac
    42961 atctgtcgtt tcttctacta atttcaataa ttcggttttt cctttttcac ttaggtttgt
    43021 ttctaattcg atatttgaat caaagtgatc ttcgattggt cgtttagctt ttcctgtaac
    43081 gatcaagatg tcttcgattc ctgatttcaa cgcttcttca acgatgaatt ggatcgttgg
    43141 tttgtccacg attggcaaca tttcctttgc catcgccttt gttgctggta aaaatcttgt
    43201 tcctaatcct gctgctggaa taactgcttt ttttactttc atatacattc gctccttcaa
    43261 aaaattgtta atgagaattc attttctttt ttcccatcac gtaacatgat ttcttttgcg
    43321 gctgttttga tttctttttg ttcatacagc acttcataga ttgtttgagt gatgggcatt
    43381 tcgatttcca tcatttgggc tagttccatc gctgcttgag tagtattcac accttcaaca
    43441 accattccca tattggctag cacctcttct agaggctgac cttgtcctaa caagttgcct
    43501 gcgcgccagt ttctggaatg aacacttgtg caagtaacga ctagatcacc tactccgctt
    43561 aagccaataa aggtcagcgg gttggcaccc attgctacac ctaaacggct gatctcagct
    43621 aatccgcgcg tcatgattgc cgcttttgca ttatcgccaa accctaagcc gtgaatagca
    43681 ccagctccaa tggcaataat atttttcaaa gctgctccca tctctacacc aatcacatca
    43741 gggttggtat agattcgaaa ataatggttc atgaacagct cttgtacata ttttgctgct
    43801 tttacatttg tgcttgccgc tgtgatcgtc gtaatgtcat gctttgctac ttcttccgca
    43861 tggcttggcc cagaaagaac agcaacagct tttctttttt ctgtcgggat ttcctctaac
    43921 aagatttcag agattctttt atgcgttccc tgttctaatc ccttacttgc gtggatgatc
    43981 actggcttcg tattcaattt ggcaactagt tcttttgcaa cagaacgtat cgctttcgtc
    44041 gggataacga atagtaccgc atctgcatct tttactgcat cttccatatc ggtgaatgct
    44101 cggatggaat cgggtagatg atgatctggt aaataacgtt gattggtgtg ttgggtgttg
    44161 atttcttcta cttgtgaagc acgatgtccc caaatccgaa cgtcatgtcc gttttcagcg
    44221 aggacttgtg ctaaagcagt cccccaagag cctggtccta aaaccgctac tctataattc
    44281 attttaccac tcctgaaatt tttttcattt ttaacgctct gaaaatcaaa taatttgttg
    44341 attttttcct aatgagcggt cataatccgg taaacttcct ttttttctac gccaaataaa
    44401 cagaatcaat gtgccgacaa ataaaacagc agacaataat tgagaaatgc ggatcacacc
    44461 taaaaagtaa aggctgtctg tgcgtaaccc ttcgataaag aaacgtccga aactatacca
    44521 cattagataa cataaaagga cttctccttt tttcaaaaga tgtggtttct tccgcaaaac
    44581 caaaagcaga ataaatccaa tcaaactcca aagtgattca taaagaaagg ttggttgtcg
    44641 atagattcct tcgatataca tgttatcaat gatgaattgc ggtaaatgca gactttctaa
    44701 gaaacttcgt gtcgtgtctg gaccatacgc ttcgtggttc atgaaatttc cccatcgtcc
    44761 gattgcctgc gccaataata cgcttggtgc agcgatatct aaaaaggtcc acaaagaaat
    44821 aaaatgatat ttggtaaaaa agtacagtgt gattgcacct gcaatcaatc ccccgtaaat
    44881 cgctaatcct cctgaacgga tattgaatat ctggattgga tcagctatat attggggaag
    44941 atcgaataaa acataataca agcgggcacc aataatggaa atcggcaatc cccacaacat
    45001 aaaatctgtc acgtcatctg cttttaatcc tacccgaaca gcttctctgc tgctgagcca
    45061 catggcaata atgattcctg atacgataat caatgcatac cagtagatag gaattcctac
    45121 aagctcaaaa gcaactcgat tgatttgtgc taacatattg tcactccttg ctagtcattg
    45181 cctgagtttt cttcaatcaa gcgacttaat ctttcttcaa atgttttcgt tgcgtcaaag
    45241 cccattgtac gtgcgcggaa attcattgcg gctacttcaa tgatgattgc aacgtttcgt
    45301 cctgttttga cagggatttt tatttgtgga atgcccactt ccgcgatttc aacggtcgtg
    45361 tcttcagagc ccagacggtc gtatttctta tctttcgccc atgcttctag ataaacagct
    45421 aactggactt gcatagagcc tcgtaccgca ctcgcaccga aaagattcat tacatctatg
    45481 ataccgatcc ctcgaatctc aatcagatgt tccaggattt taggaggttc tccgattacc
    45541 gtcagttcat cttgctgata gacatctact cgatcgtctg cgatcaatcg atgtccgcgc
    45601 ttaatcagtt ccaacgccgt ttcacttttc cctatcccac tgtccccttg aattagtaca
    45661 cctaatccgt agacatcgac taacacaccg tggacacttg ttcgaggggc taagcgtcca
    45721 tctaaataac tagataattc acctagcagc cgggacgttg agataggcga acgcagcaca
    45781 gctatcccat tttcattggc tgcttggatc atttcttccg gagccggcaa tcctcttgaa
    45841 ataataaatg cgggcatatc ttcactacat aatcttctca taatgatcaa acgctcttct
    45901 gggatcatcc gttccgcaaa actgatttct ttactgccaa atagctgtaa acgattatgg
    45961 gaataataat taaaataacc ggtcaactct agtcctgggc gtgagatgtc cccagtcacg
    46021 atgacgcggt ctaaactttt ctcgtcgcct gtgacgattt ccaaagataa tttttttact
    46081 aattggctaa cttttacaac ttctgacatt catgctacct catttctatt agagtgttct
    46141 ctatcatttt atcattgtct agccaaaagt actaccaatt aaaaaaaacg tttttattta
    46201 attaccaatg taatagaaaa cgcattcttt attctaaac
//
LOCUS       DAZKKZ010000017        44934 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.017, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000017 DAZKKZ010000000
VERSION     DAZKKZ010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 44934)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44934)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44934
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.017"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..1008)
                     /locus_tag="ACG8LA_001016"
     CDS             complement(<1..1008)
                     /locus_tag="ACG8LA_001016"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFQ0203331.1"
                     /translation="MKKKSIILAATSALAVLTLAACSGDTNKDIATMKGGTITVSDFY
                     DEAKLESSNQSLVQRMIIYKVFNNKYGDKVTDKQVDAEYDKQAKSLGDTFESQLEAAG
                     YTKDTYKEYIRNNLAFEAGLKAHVDITDDDLKTAWKSFHPEVEAQIIKLSSEDEAKDV
                     KKSADDGDDFSKLAKDKSTDTETKEDGGKVKFDSTTTTIPAEVKEAAFKLKDGEISDV
                     ITTTNPTSYATEYYVVKMVKNQNKGNDMDKYKDQLKDIATETKLSDNAFTTKVIGEEL
                     KDANVKIKDDAFENVLSAFTTTSSSTKDSSETTASTKSSDTKSTDSTKESSTEETTDS
                     SK"
     gene            complement(1188..1532)
                     /locus_tag="ACG8LA_001017"
     CDS             complement(1188..1532)
                     /locus_tag="ACG8LA_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HFQ0203332.1"
                     /translation="MIKNFFKGLLFGAAAGTVGGLLLAPRSGNETRKKLIEELEEATT
                     LTNDLNNSLNHFKSALIETKETAESVIPAFQEAIKKDIEDFKFQAEPRITQINEQVEK
                     LKADLPEYPEQI"
     gene            complement(1525..1959)
                     /locus_tag="ACG8LA_001018"
     CDS             complement(1525..1959)
                     /locus_tag="ACG8LA_001018"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HFQ0203333.1"
                     /translation="MENCIFCKIINQEIPSYKIYEDDKVYAFLDISQATKGHTLVVPK
                     RHVADIFEYDPELAGEVFSRVPKIAQALEKAFPEMKGLNILNNNRELAYQSVFHSHIH
                     LVPRYSKEDDFSIHFVNHQDSYGSEELKAIQETIVKQVSCDD"
     gene            2097..2834
                     /locus_tag="ACG8LA_001019"
     CDS             2097..2834
                     /locus_tag="ACG8LA_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0203334.1"
                     /translation="MSLIIDHVTGGYGHLPVLKDISFDVQPGEIVGLIGLNGAGKSTT
                     IKHIIGLLEASKGTIEINHLSLKKNTEEYRKQIGYIPETPSLYEELTLREHIEVTAMA
                     YDIPMDIAMKRAEKLLETFRLSNRLDWFPANFSKGMKQKVMILCAFLIEPSLYIIDEP
                     FLGLDPLAINALLELMVEMKKEGAGILMSTHILATAEKYCDRFVVLHNGEIRADGSLE
                     MLRKEFQLPDSSLDEIYIALTKEQAHE"
     gene            2827..4038
                     /locus_tag="ACG8LA_001020"
     CDS             2827..4038
                     /locus_tag="ACG8LA_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFQ0203335.1"
                     /translation="MSSFFQKRLARHQKKMMKYMRYVLNDHFVLVCLFLIGGVGLYYS
                     NWLKTLQPPFAIGGLIISVFWMLCLFVGKMATFAEAADIVFLLPKEKEMQTYLERAFR
                     YSCIFPLIFLILACGLAMPLVVVSTEQSFSMFFVYLIILWSLKFSHLQIKRAELFRLD
                     QQVIRYWKLGWFFSSLIFLFLSFYWLIWAGIAGALVQASLYYWFLWKQQEKGLDWEKM
                     VHVEEHRLHQIYQFINLFTDVPEITAKIKRRRYLDPILTHIKRESKNTYLYLFARRLA
                     RGSDFSGLYFRLVIIGGLLIAGVVDFYFSLIIGFLFLYLIGFQLLPLANQFRYMVLVQ
                     LYPIHKNQKKQAIQYLLTWVLIIASVIFGLIAAVVLDGQQRWVPLAAYLIVTMLFVKL
                     YVPTRLKKMSD"
     gene            4242..5024
                     /locus_tag="ACG8LA_001021"
     CDS             4242..5024
                     /locus_tag="ACG8LA_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HFQ0203336.1"
                     /translation="MMEFQLDQEWRLRPIKGDTGKTYIGMRDEDKVFIKRNTTPMLAA
                     LSREGITPKLVWTKRTGNGDTLTAQEWLEGRLLTPNEIGQRNDVIDVLYHLHHSNSLK
                     TMLTRIGGRVMTPEKMLQKYEKELPEELQKNQFLQIVHRFLREQIPSIDKENLSVVHG
                     DVNHRNWLVCKNYLYLVDWDSIMFADPAVDIATILGNYVPLSSWNQWLISYGIRPTDE
                     MLEKFHWYAAMNLLQEITRYCKREDHRRMNEEILQLKRIFSG"
     gene            5094..5756
                     /gene="trmB"
                     /locus_tag="ACG8LA_001022"
     CDS             5094..5756
                     /gene="trmB"
                     /locus_tag="ACG8LA_001022"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008176 - tRNA
                     (guanine(46)-N7)-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HFQ0203337.1"
                     /translation="MRVRNRPGAAEMLAAHPNFVISDPTLWKGKWNELFENDHPIHIE
                     IGMGKGQFITGMAKAHPEINYIGVEMQVSVVSIALDKLIEQPLPNLKLLHVDGSALTE
                     YFADSEVDQIYLNFSDPWPKKRHEKRRLTYKTFLAVDEQILRPNGEIHFKTDNQGLFE
                     YSLASFSQYGMILKQVWLDLHQSQFEGNIMTEYEEKFSSKGQRIYRVEAQFQDKTKKK
                     SL"
     gene            complement(5854..7608)
                     /gene="ade"
                     /locus_tag="ACG8LA_001023"
     CDS             complement(5854..7608)
                     /gene="ade"
                     /locus_tag="ACG8LA_001023"
                     /EC_number="3.5.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000034 - adenine deaminase activity
                     [Evidence IEA];
                     GO_process: GO:0006146 - adenine catabolic process
                     [Evidence IEA];
                     GO_process: GO:0006168 - adenine salvage [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HFQ0203338.1"
                     /translation="METTLRKYIEVASKKKPADLVIKHAKIVNVFTKEIMEKDVAICE
                     GMIVGIGEYEGKSVHNANGQYLVPGFIDGHVHIESSLLSPSEFSKVSLLHGVTTVVTD
                     PHEIGNIAGSTGLEFMIEDARQTLMNIFFMLPSCVPVTPFETNGANLNAKKLAPFLQK
                     PEVLGLAEVMNYQAVANNETDILEKIQLMHQHKKKIDGHAAGIGMEELNVYPAAGIRT
                     DHEATTAKEAKERLDLGMYLMVREGTVAKDLASLLPAITPENSRRCFFVTDDKLINDL
                     VKEGSIDHIVRQAIALGIDPLQAIQMATLNAAECFDLKTLGAIAPGYQADFFLTDDLT
                     KLPIHEVFYKGTLVVQSGQLQDHLFADHSNSYTCCLPKLNAQPLNPHSLELLLSSSQA
                     HVIEIIPNSLVTKDLVEKVDRQGERFIPSIEKDQLKIAVIERHHQTGNIGLGIVKGFQ
                     LKQGAIATTIAHDSHNLVVVGTNDEDMLYAANLLIQKGGGMTVVNNQQEIACVSLPIG
                     GIMTQEPFSIVYEQLNELITKAHQLGAAKTFDPFLTLSFLTLSVIPELKITDKGLFSF
                     SRFQLIPPCGKTDEINTF"
     gene            7740..8669
                     /gene="comGA"
                     /locus_tag="ACG8LA_001024"
     CDS             7740..8669
                     /gene="comGA"
                     /locus_tag="ACG8LA_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus ATPase ComGA"
                     /protein_id="HFQ0203339.1"
                     /translation="MEIKRLSDQMISESFAKHAQDVYILPASEVFYIYFRYGKKRTFW
                     KKVSSADGQQLISRFKYLGQMDIGEKRKAQLGAFTYSLEKQEVRLRLSSVGDYLQRES
                     LVIRLLYGTFETPHRCFSSRDFATILQKTVRRGLYLFSGPVGSGKTSLMYRLALEEKL
                     QVITIEDPVEIEEPFFLQLQINPKIAQTYDTLLRLALRHRPDLLIIGEIRDESTAHAA
                     VRAALTGHRVFATVHARNLEGTLVRIHELTKKKEELSECLAGVIYQELLEDANHHPSV
                     LWSYQFMEEESVKKSWEESYEEAQENIWQSELF"
     gene            8626..9675
                     /gene="comGB"
                     /locus_tag="ACG8LA_001025"
     CDS             8626..9675
                     /gene="comGB"
                     /locus_tag="ACG8LA_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus assembly protein ComGB"
                     /protein_id="HFQ0203340.1"
                     /translation="MKKLRKIFGSQNYSKGLTRSQQNQFAQTMGELLLSGFSLQESLY
                     LLLTIRSFPPVILANIQHQLKEGQAFSEVLSQIGYGAEQLVQIELAERHGNLPTTLLE
                     IAKQFRLVEGFRNDLKKLLAYPMLLLTFLLGILFSMRLFVLPQLIGSGMVMQEHWGIQ
                     LIQVFHWYVLLFILAVTLLALLVRYRLMKLSPVDQSEWISRQLLIGPIYSLYQSAYLS
                     LEIGKLFHEGFELRQIIVCLKETKQESLIQHLASKLIQGLEAGMSLAEQFQNYRFLSE
                     EFSKIVLQGEAKGSLGKELIFYSEWTRKQLFKRLHHWMHFIQPIIFLGVAALILLVYA
                     AVLLPVYGSIEEVLP"
     gene            9672..9950
                     /gene="comGC"
                     /locus_tag="ACG8LA_001026"
     CDS             9672..9950
                     /gene="comGC"
                     /locus_tag="ACG8LA_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0030420 - establishment of competence for
                     transformation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus major pilin ComGC"
                     /protein_id="HFQ0203341.1"
                     /translation="MKKRKISYYSGFTLIEMLIVLLIISVLVLLFVPNLSRYRNHVDQ
                     ESREAIIQLVDTQKELYALQNNGRVPTVEELLNEGYIKREHAEIYQRP"
     gene            9925..10395
                     /gene="comGD"
                     /locus_tag="ACG8LA_001027"
     CDS             9925..10395
                     /gene="comGD"
                     /locus_tag="ACG8LA_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGD"
                     /protein_id="HFQ0203342.1"
                     /translation="MQKSISGLEGKVLASGYTLFESLLLILLLTTILSFPVLAFSAWK
                     NELAVYQFFGQFEKRIYSTQKIAIVNQIQTGFYWNSEENQIIFHVPNPDKINWEVLDI
                     PDEITLKRHASITFAARTGNESSLKAYQFYWEEKERTITYQFQIGSGRYTKRIE"
     gene            10367..10714
                     /locus_tag="ACG8LA_001028"
     CDS             10367..10714
                     /locus_tag="ACG8LA_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0203343.1"
                     /translation="MVAIQKELNKTGFVLLESLTALMIASVCVYLVSFGQLFLLQAEK
                     KSGEELLFIRMIYEDIKTQRMYHKRPERREEMIPYDIQIVDNNGVIEKVFVNMEKEAI
                     SIEKTSNSSIYAD"
     gene            10677..11102
                     /gene="comGF"
                     /locus_tag="ACG8LA_001029"
     CDS             10677..11102
                     /gene="comGF"
                     /locus_tag="ACG8LA_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGF"
                     /protein_id="HFQ0203344.1"
                     /translation="MKKQVIPAFTLIECLIGLMILSSLLLTFNLLIQQTIQVSEFLQR
                     KDQKEWLIFLAQLEEELKSSHNVSVKNQQLHYTIEDKQYIIERYQAMIRKRRTSGGHQ
                     PMLTSITELQLLEKEHTISFYVHFENGEDGYAIWTKNDQ"
     gene            11074..11433
                     /gene="comGG"
                     /locus_tag="ACG8LA_001030"
     CDS             11074..11433
                     /gene="comGG"
                     /locus_tag="ACG8LA_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGG"
                     /protein_id="HFQ0203345.1"
                     /translation="MPYGQKTISRKCYKGSILFSVLLLFLLCTFLLMAALESYRLSMD
                     LNIRIKNYYIAKIMKQMALSEQSTLAESSEGVFYYTTGSVTYQWVQQSLFLEVEVSPF
                     IFRFTEEVKNDTDTSTE"
     gene            11605..12612
                     /locus_tag="ACG8LA_001031"
     CDS             11605..12612
                     /locus_tag="ACG8LA_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFQ0203346.1"
                     /translation="MLPEKMEQGFNQNLEAIQLLQNALGTSFLEAYVENAENLIDDYQ
                     VRVVDGVPTKETTQRITALYEELKKLSFEPEEWRRLSQLLLLKGSQTEHLQANHQLTP
                     DSIGFLFVFLIEQLYTNKKAPVKILDIAAGMGNLLLTVLLNLSNAGYQTEGIGVDIDD
                     TLLAVAASTSDLTQANVQYFHQDGLQELLIDPVDFAISDLPIGYYPNDEKAKEFLTST
                     EEGHSYAHHLLLEQSMKYVKPDGFGLFLMPSGFLETDQSEEIKKWFKEEGYLQGMIQL
                     PDELFRNKQSQKSILILQKKGPQAQQVKEVLLVKLASLKEPEKVTEFFNEFKNWKSSA
                     L"
     gene            12637..13821
                     /locus_tag="ACG8LA_001032"
     CDS             12637..13821
                     /locus_tag="ACG8LA_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate/propionate family kinase"
                     /protein_id="HFQ0203347.1"
                     /translation="MSKTIAINAGSSSLKWQLYQMPEETVVAKGIVERIGLQDSIFTI
                     KYGDNQKFEQIMDIENHEVAVKMLLDQLIELQILSSYDEITGVGHRVVHGGETYGDSV
                     VIDEKVMDRIAELAEFAPLHNPANLMGIKAFKKILPDILSVAVFDTSFHSTMPKQNYL
                     YSLPVSYYEDFKVRKYGFHGTSHRYVSERAAKLLNKPIEELKIITCHLGNGVSITAVD
                     GGKSMDTSMGFTPLAGVTMGTRSGDIDPAVLPYLMEKLEIDIDEMINVLNKKSGLLGL
                     TGLSSDMRDLEKNYEKEHIRLAYDIFVDRIRKYIGGYVTTMNGVDAIVFTAGIGENDG
                     HVRSEIIKGMSWFGCEIDPALNELRGEEVDISTKESKVRVLVIPTDEELMIARDVERL
                     RG"
     gene            complement(14258..15841)
                     /gene="abc-f"
                     /locus_tag="ACG8LA_001033"
     CDS             complement(14258..15841)
                     /gene="abc-f"
                     /locus_tag="ACG8LA_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protection-like ABC-F family protein"
                     /protein_id="HFQ0203348.1"
                     /translation="MIIQAISIKKTIGGNPLFEDLSCQIEAGEKIVLVGINGTGKSTF
                     LQILTGREGVDSGVISRKKGLKIGTVEQELTVSEATVNHYLLHSAAEIQDLKQQMSRY
                     EALMTEPDTNLEKCLARYGELQHRFEELGGYVLEDRIAAILQGLGIPHRQEARLTELS
                     GGERVKVALAKILAADADLLLLDEPTNHLDLNSIRWLENYLQNTKKSVLVVSHDRQFL
                     DQVTTKTWELEEGALIEYPGNYSRFRVLKEARLAELTKNYELQQKEVQRLKVMIRRFR
                     QWAHEGDNESFFKKAKELERRLAKLTLVKPPPPPKNRLQSLSNGGKSGKEVFIIQNLH
                     QQYADQVLFKDSSFAVYRGDHLAIIGDNGAGKSTLLKLLLGEEKPYGGTIKLGSSLQI
                     GYLPQQLQFADPDSRLLAYAITLTGNEEVARRQLAKSGFYQSDVGKRIKDLSGGEKIR
                     LALLKLFLEKINVLILDEPTNHLDSYAREEIEEMLQDYQGTLLAVSHDRYFLQQHFQE
                     ALVIDQEQISRQPLGQLID"
     gene            complement(15946..16074)
                     /locus_tag="ACG8LA_001034"
     CDS             complement(15946..16074)
                     /locus_tag="ACG8LA_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0203349.1"
                     /translation="MMRMTKITSNENYQRYHIAFSHAIGFTVAVDGTSLSKTVEFT"
     gene            complement(16419..16562)
                     /locus_tag="ACG8LA_001035"
     CDS             complement(16419..16562)
                     /locus_tag="ACG8LA_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="portal protein"
                     /protein_id="HFQ0203350.1"
                     /translation="MEVSDESDTKKYEVSMADTDFIAKLKFYFGFGYREKASATFGKS
                     FKN"
     gene            complement(16785..17264)
                     /locus_tag="ACG8LA_001036"
     CDS             complement(16785..17264)
                     /locus_tag="ACG8LA_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HFQ0203351.1"
                     /translation="MLQQYKKIMVAVDGSDEAELAFKKAVNVAIRNNGELLLAHVIDT
                     RSFQTVSSFDGMLAEQATEMAKQTLADYESNAKKAGLNNVTSVVEYGSPKQIIAREIP
                     EDNQVDLIMLGATGLNAVERLFIGSVSEYVIRNAACDVLVVRTDLENQLPAKDHTKA"
     gene            complement(17337..17621)
                     /locus_tag="ACG8LA_001037"
     CDS             complement(17337..17621)
                     /locus_tag="ACG8LA_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0203352.1"
                     /translation="MIRILMIIATLVLLFVSYYLFNKQDIFFVLINKNDKNQGFLQFY
                     GAAYAVLGVMGILTAFFNQRFIALVFLLIVIIVSATFSIRFAKKIAEPKQ"
     gene            complement(17699..17893)
                     /gene="ssrS"
                     /locus_tag="ACG8LA_001038"
     ncRNA           complement(17699..17893)
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="ACG8LA_001038"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            complement(17965..19251)
                     /locus_tag="ACG8LA_001039"
     CDS             complement(17965..19251)
                     /locus_tag="ACG8LA_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HFQ0203353.1"
                     /translation="MQQPLAYRMRPRTIDEVVGQQHLVGEGKIIRRMVDARMLSSMIL
                     YGPPGTGKTSIASAIAGSTNYAFRMLNAATDSKKDLQVVAEEAKMSGTVILLLDEVHR
                     LDKTKQDFLLPHLESGRIILIGATTENPYITINPAIRSRTQIFEVKPLTEQDIQLAVE
                     HALRDKERGLGQQAIQLDEDALLHLSRATNGDLRSALNGLELATLSTPSDKEGRIHLT
                     LSIIEECVQRKALTHDKNGDAHYDVISAFQKSIRGSDVDAALHYLARLVEAGDLASIC
                     RRLMVIGYEDIGLGNPAAAARTVNAVLAAEKLGLPEARIPLADVVVDLCLSPKSNSAY
                     MALDAALADIREGKAGDVPDHLRDSHYKGAKSLNRGVGYQYPHHFDQAWVNQQYLPDK
                     LKNAQYYQPKDTGKYEQALGQQYYRIKEWKKHPPKN"
     gene            19389..20060
                     /locus_tag="ACG8LA_001040"
     CDS             19389..20060
                     /locus_tag="ACG8LA_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="HFQ0203354.1"
                     /translation="MTDKQKIDEFFWNKTTPEVARDLLGMYLEHDTPEGRLAGYIVDA
                     EAYLGPEDEAAHSYGLRRTPRVRAMYEKPGTIYLYTMHTHRILNIITQPEGIPQGVMI
                     RAIEPAAMIDQMSKNRGGKTGPDISNGPGKLVEALAIPQELYGQSIADSSLRLVFEKK
                     KTPKKINALPRIGIPNKGVWTEKPLRFVVSGNPYISLQRKNQIEKDWGWRKENEKEGS
                     INIFR"
     gene            20026..20514
                     /locus_tag="ACG8LA_001041"
     CDS             20026..20514
                     /locus_tag="ACG8LA_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HFQ0203355.1"
                     /translation="MKKKDLLTYLDEIIEKQVTDYDVALDWDTKNHTIEIVVRLFAEN
                     KAQFEIDDAEGIVSQEPIIEFEDGVLLFNPQKSVFDERNYLAVIPYEGKKGLAKSVAD
                     SLVEYLNEVLAQGQSDLLDFLDEDDDEAVFELHWDNQQLAELVEVKQQNEADTYLPYP
                     SY"
     gene            20527..21474
                     /gene="prmA"
                     /locus_tag="ACG8LA_001042"
     CDS             20527..21474
                     /gene="prmA"
                     /locus_tag="ACG8LA_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HFQ0203356.1"
                     /translation="MKWNEVKVETESEAVEAVANILMEAGASGVAIEDSLDVEHFQSD
                     QYGEILDKNDFTSLKEGALVMAYFPETTFLPEILPFIKDRITQLPEFGLAIGKNKVTV
                     SEVEESNWATAWKKYYHPVRITRMLTVAPSWENYQTEDPLEKIITLDPGMAFGTGTHP
                     TTSLTLTALETVLRGGETLLDVGTGSGVLSIAAKYLGAKDVYAFDLDEVAVRSAKENM
                     DMNEIAKDVHVSANDLLTGIEIESDVIVANILADIILLMIPDAWRLLKQTGTLIVSGI
                     IEEKKQMVLDAMLEQGFIVDQIFQQKDWYAIILKKPEVE"
     gene            21475..22239
                     /locus_tag="ACG8LA_001043"
     CDS             21475..22239
                     /locus_tag="ACG8LA_001043"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HFQ0203357.1"
                     /translation="MQRYFLKESYESKDYFVLEGENYHHIVRVMRMEPEDEVFLAFND
                     QIAIVAEITEITEEAVYLKEIKKEENQKELPSSITIASGYPKGEKLDWIVQKSTELGA
                     QAFLGFPASASVVKWDAKKRMKRQQRLEKIAQEAAEQSHRQIVPSVELLETKQDLFER
                     LDDYDVVLVAYEESAKQGEKSNAAKILSETKPDSRILAVFGPEGGLSRDEVDYFVEHK
                     GILCGLGPRILRTETAPLYLLSAASYQWELMNPSFS"
     gene            22472..24685
                     /locus_tag="ACG8LA_001044"
     CDS             22472..24685
                     /locus_tag="ACG8LA_001044"
                     /EC_number="2.7.6.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016616266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0015970 - guanosine tetraphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HFQ0203358.1"
                     /translation="MTKEEILTGPGVIKLVSQYMGPEHVAFVEKACEYATAAHDGQFR
                     KSGEPYIIHPIQVAGILADLKMDPHTVATGFLHDVVEDTEITLEDLREEFGDDVAMLV
                     DGVTKLGKIKYKSHEEQLAENHRKMLLAMAQDLRVIMVKLADRLHNMRTLKHLREDKQ
                     RRIAQETLEIYAPLAHRLGISRIKWELEDTALRYLNPKQYYRIVHLMQTKREEREKYV
                     SGTVEDIRIATEELGIFAEIYGRPKHIYSIYRKMKDQKKQFNEIYDLLAIRVIVDSIK
                     DCYAVLGAIHTKWKPMPGRFKDYIAMPKANMYQSLHTTVIGPAGNPVEIQIRTQEMHE
                     IAEFGVAAHWAYKEGKNEKVEPDGMTKQLSWFHEILELQDESYDASEFMEGVKGDIFS
                     DKVYVFTPKGDVTELPKGSGPLDFAYSIHTDIGNKTTGAKVNGKMVQLDYKLKNGDII
                     EIMTSPNSFGPSRDWLKLVATSKARNKIKRFFKAQDREENVIKGHESVVKCITDLGFT
                     PKDILTKNKLQEALDRFNYQTEDDLYAAVGYGEVSPLTMANRLTEKERKEQKIEQQKQ
                     EAEEIMNQPKKEPDKMKVRHEGGVVIQGVENLLIRISRCCNPIPGDDIVGYITKGRGI
                     SIHRRDCPNVQPDKPNVAERLIEVEWEDTSNTRKEYDADLEIYGYNRSGLLNDVLQTV
                     NALTKNLNSVEARTNKDKMATIHLTVGIQNLSHLKSIVDKIKAVPDVYSVRRTNG"
     gene            24696..25142
                     /gene="dtd"
                     /locus_tag="ACG8LA_001045"
     CDS             24696..25142
                     /gene="dtd"
                     /locus_tag="ACG8LA_001045"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004045 - aminoacyl-tRNA hydrolase
                     activity [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacyl-tRNA deacylase"
                     /protein_id="HFQ0203359.1"
                     /translation="MRAVVQRVSKAAVSVDQQEIGKIGYGLLVLLGIHETDTQKDVDY
                     LVKKIAQMRIFEDEQGKMNISVEDVGGQILSISQFTLFADTKKGNRPSFVEAARPETA
                     IPLYESFNEGIRSRGITVATGQFGADMSVSLVNDGPVTIIIDSKNK"
     gene            25313..26572
                     /locus_tag="ACG8LA_001046"
     CDS             25313..26572
                     /locus_tag="ACG8LA_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004497 - monooxygenase activity [Evidence
                     IEA];
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA];
                     GO_function: GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome P450"
                     /protein_id="HFQ0203360.1"
                     /translation="MKEVPVVDIKITDLKKLYQKGYNMLEELRHEADAPVVKAKIFNK
                     EAITIYGSSAAKVFYDPRNFKRKGAMPKLVLKTLFGQGGVQTLDGAAHHHRKNIFMDL
                     MTPERMEDYHRILDKNLTQALEAQHGQFELFDLSKMVFFTSICEWAGINLSAISKDEV
                     EKLAEYQISMISGTFTSPIDHIKGVENRKKSEKWAQGLIEEARQNPVAGKENVALYAF
                     ANATDLDGQLLPLEVAAVELLNIIRPTVALTVWAALMGHALFSRPDLYQQLKNDFSTL
                     QDPFIQEMRRYYPFFPMLPAISLKEVEVDGYRIPEGSWVILDLYGTDHDERTVEAPDS
                     FMIKRYVGKAKDISYKEEYEMIAQGGGNFRQMHRCAGEWITLHSLRVFSDQLVNKFEF
                     SVPEQDWTIPFNQFPTYPNSRALLYKN"
     gene            complement(26661..27608)
                     /locus_tag="ACG8LA_001047"
     CDS             complement(26661..27608)
                     /locus_tag="ACG8LA_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HFQ0203361.1"
                     /translation="MAEIRIGHSQVYAEQLGLGANAVGGHNLFDGLEDETGKQVVRTA
                     LNSGINLIDTAYAYGNGRSEELIGEVLKEKEYDRSRVVIATKAAHVPNKGRTFDNSPE
                     FLKQSVEDALKRLQTDYIDIFYIHFPDESTPKNESVATLHELKEAGKIRAVGVSNFTL
                     EQLKEANADGYVDVVEDKYSLIHRQAEKELFPYLEKNKISFVPYFPLASGLLTGKYEL
                     GEEKQFGEGDPRKRNPDFQGERFREILTAVDVLRPIAKRYQATPAQLVLAWYMKNPRV
                     SVVIPGAKRPEQVSDNVQALDLHLSNEDYQTIDEAFRGF"
     gene            28002..29294
                     /gene="hisS"
                     /locus_tag="ACG8LA_001048"
     CDS             28002..29294
                     /gene="hisS"
                     /locus_tag="ACG8LA_001048"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004821 - histidine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006427 - histidyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HFQ0203362.1"
                     /translation="MSFQRPKGTNDILPGESEKWQFVEETARLLFRDYQYNEMRTPIF
                     EHYEVISRSVGDTTDIVSKEMYDFYDKGERHVTLRPEGTAPIVRSFVEHKLFGPEYAK
                     PFKTFYMGPMFRYERPQKGRLRQFHQIGVEAFGSENPATDVESMVMALDFFKQLGITQ
                     IRLVINSLGDKETRQAYRQALIDYLLPFESELSEDSKRRLHENPLRVLDSKDKRDQKF
                     VAEAPSILDYLSEPAQKHFDTVVSMLDALAVPYEIDSNMVRGLDYYTHTIFEIMSDAP
                     KMGAQATICAGGRYDNLVEELGGPSTPGFGFAMGIERLLLTMEAEEVVIPAFNELDAY
                     VVALGDETNIEALKVVQAIRNFGFSADRDFMNRKAKAQFKTADKANAKLVLVIGEDEL
                     ASQTINVKAMASRKEKSFPLEEIYEHFDEVYDEMTLFE"
     gene            29309..31078
                     /gene="aspS"
                     /locus_tag="ACG8LA_001049"
     CDS             29309..31078
                     /gene="aspS"
                     /locus_tag="ACG8LA_001049"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA];
                     GO_process: GO:0006418 - tRNA aminoacylation for protein
                     translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HFQ0203363.1"
                     /translation="MAQRTIYCGLVSEQQLEQTVTLKGWVQKRRDLGGVIFIDLRDRE
                     GIVQIVFNPEINKEAWEIADKCRSEYVIEVTGEVRRRGENAVNPKMATGEFEVIASEI
                     VILNQAKTPPFQIEDDQAISDEIRLKYRYLDLRRPKMTKNIKLRNATTKAIRHYLDDN
                     DFLDIETPYLGKSTPEGARDYLVPSRVHAGHFYALPQSPQLFKQLLMNAGFDRYYQIV
                     RCFRDEDLRGDRQPEFTQVDIETTFLTAEEIQTYTEGLIAKVMKEVRGIEVTLPFPRM
                     TYDEAMARYGSDKPDTRFDMELIDLSDTVKEVEFKVFQMALENGGVVKALNAKGAADR
                     YSRKDMDQLGQYVGQFGAKGLAWLKVEEDGLKGPIAKFMGEATEAIIKATDAKPGDLL
                     MFGADKSEIVAAALGAIRTRLGKELGLIDESKFNFLWVTDWPQFEFSEEEGRYVSAHH
                     PFTMPKEEDIPLLAEDPAKVYAEAYDIVLNGYELGGGSIRIHTRELQEKVLETLGFTK
                     EQMEEQFGFLLTALDYGFPPHGGIALGLDRFAMLLAGEDNIREVIAFPKNGKAADVMS
                     DAPSMVSPLQLFELNIDVTNIEE"
     gene            31187..32062
                     /locus_tag="ACG8LA_001050"
     CDS             31187..32062
                     /locus_tag="ACG8LA_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFQ0203364.1"
                     /translation="MKKTFENWAYHDYTTKLSVSIVYALIASVALNFFYQPGHIYSSG
                     ITGLAQILTTLSKSLIGFEVPVSTTLYLLNIPLFVLAWLKIGKKFTIFTFITVTLTSL
                     CIHILPETVLSTDPIICALFGGAVMGLGIGLALRNGLSSGGLDIVSITIRKKTGKSIG
                     SISIYFNALIVFVAGILFGWQYMFYSTLSIFVSGKVTDVVYTKQKKMQVMIVTKHPEK
                     VVNEIQNCMRRGITIINEAEGAYKHDKQTVLMTIVTRYELPLLREAMKASDPQAFVSI
                     AENVQILGRFYEDGI"
     gene            32328..34211
                     /locus_tag="ACG8LA_001051"
     CDS             32328..34211
                     /locus_tag="ACG8LA_001051"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HFQ0203365.1"
                     /translation="MEKQKRLKNSRYITGFDGLRSLAVVGVIFYHLLPTSMKGGYLGV
                     PIFFVVSGYLITDLLRQEWEQNGKINIWQFYVRRMKRLYPALVFMLVTASAYITLFQR
                     GLLNNLRGVVVSSLLYVNNWWQINNGLSYFDRFANESPFTHIWSLAVEGQNYLVWPIL
                     FVLLMVFVRKRKWIFYTVLGTSFLSAILMMILYTPGGDPTRVYYGTDTRLFSIWLGSA
                     LAFVWPSTRLKKNIPKQAKNILNIAGGISLLALILCFFFLDDHYNFIYYGGMLLVSLL
                     CVVLVAVTAHPGASLNRWLTNPVFTWIGKRSYGIYLYQFPVMIFYEAKVTDIADHVLL
                     HTLVEITLILIISELSYRYVERPLARFDYGRTFQVMKGWFSKPIISKSKPWVVPGTLL
                     VAIALVGFVTAPKNAVTADQKQLQAKIAESKKLAEETRNNSENTTSSVDQAILDKYEL
                     SKAQGNKAQKLELTAFGDSVMLDAATDLQELYPKVVVDGDVGRQLYASVPYIEKLKEQ
                     DLLKDTVLIGLGTNGSFSEAQFDSVMDAIGDRKVYWVNVRVPTKRWQNDVNAMLEQMT
                     KKYDNMTLIDWYSYSNDHSDWFYDDQVHPNPEGMTHYIHLVSEALLGGSSSTNSSETN
                     VTE"
     gene            complement(34286..34570)
                     /locus_tag="ACG8LA_001052"
     CDS             complement(34286..34570)
                     /locus_tag="ACG8LA_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HFQ0203366.1"
                     /translation="MANEHYFYVLFCKDQTFYGGYTTDLSRRLEEHNNGTGAKYTRLQ
                     KRRPVKMIHAEVFSSRSEATKAEAAFKKLTRKQKERYLQTHSTVLLPESI"
     gene            complement(34560..35294)
                     /locus_tag="ACG8LA_001053"
     CDS             complement(34560..35294)
                     /locus_tag="ACG8LA_001053"
                     /EC_number="2.1.1.223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008170 - N-methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016430 - tRNA
                     (adenine-N6)-methyltransferase activity [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HFQ0203367.1"
                     /translation="MLHEDERIDQLYAEDIKIIQSSKVFSFSLDAVLLAHFSRVPKKG
                     KIVDLCAGNGAVGLFLSKRTQAAIDAIELQPRLADMARRSIALNHLNEQMTVHTIDLK
                     DSLSVVRHNSCDLVVCNPPYFKGLPTNKTNPNKHLAIARHEIHTTLEEVIDISSKLLK
                     TNGRFTMVHRPDRFLEIIQVMEDYRIAPKRIQFVYPKPGKEANILLVEGIKEGKLDGF
                     KVAPPLITYNMDGEYTAEIREMLYGK"
     gene            35423..36046
                     /locus_tag="ACG8LA_001054"
     CDS             35423..36046
                     /locus_tag="ACG8LA_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysophospholipid acyltransferase family protein"
                     /protein_id="HFQ0203368.1"
                     /translation="MFYRFMRGVVRVLLALVNGNARYENKEVLPQDENYILVAPHRTW
                     WDPLYLAVAAAPKEFSFMAKEELFKNPVLRFILTRSNAFPVKRENPGPSVIKTPVKIL
                     KSTNLSLIMFPSGTRHATELKGGMALISRMSKAKIVPAVYQGPLTLGDLFKRQRVTVR
                     FGEPIDLSDIKKTDKEGMAEIERRTQAAFDKLDKEVNPDFKYEVKKK"
     gene            36238..37359
                     /locus_tag="ACG8LA_001055"
     CDS             36238..37359
                     /locus_tag="ACG8LA_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HFQ0203369.1"
                     /translation="MRFLHTADWHIGKKLQGYDLIEDQRHVLSSILDIAKEEKVEAIV
                     IAGDLYDRSVPAVDAVELYNELMVDWNLKEKIPIFAISGNHDSSTRLSAGTPWFSYSN
                     YFLRTQLAEAFEPVEFKNVQFFFLPYFEPIAARLYFEDDNIRTIKQAVAKVIDKMQEL
                     FDSEKKQVLISHFFVMGSVKSDSETKIEVGGLDSIPGELLTPFDYVALGHLHNQAALR
                     QDNARYSGSPLKFSLSEINQKKGVWIVDLTTGLELNFREIEPLHDIEEITASFKELLD
                     PAFYQSVNRENYIYIYLTDRTIIPNMMNQLRQIYPRILGIERANGRAEQTKRKRKVLE
                     MKDPQKLAEAFFSEMTEEQLTANQEKWLGETLQEIMEME"
     gene            37366..40494
                     /locus_tag="ACG8LA_001056"
     CDS             37366..40494
                     /locus_tag="ACG8LA_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006302 - double-strand break repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFQ0203370.1"
                     /translation="MKPKKLQLKNFGPFINETVDFSRLTEAPLFLISGKTGAGKTTIF
                     DGITFALFGETSGRLRSGKEMRSLFATPDEETSVTFSFEHQQMSYEIERKPEQVLAKR
                     KGNGTKKQAAKVTLTIFDGKGKEIKQITKRTEADQLIRELMNLDAKQFSQIVLLPQGE
                     FRNFLVSSSSDKETVLRHLFGTQFFQQFNERLKEKAKQQQQKLDHLEQELHLLQKRFV
                     LVKEEEPAAGFEAVLAQWTNHQAILEKQITEEKEALTELQEKQKQLENSYYRFESLKK
                     SYEEKTILINKQKELAAQKDEIEEKKRWIGYYEFTQRLVEPIQRLQEIKVEKIELSQK
                     SSEQTKKLAMTTQNYEEWQKNEANRVRRQTKIKEAAQKLQNKQMMVPIVESLRSKKQD
                     AEQLTISLDKEELNAEKLYQNLAIYQERTRILQENLLDQEKLQEDRLAFGQLKYLDEK
                     QQEIEKQKAKDTGSLAQIREELKKATEEITKNSQLLKEQTEQAEQLKSQWAKQQIARL
                     QLFLRPGEPCLVCGSTEHPIQQLKHEQPNKEDILKVEQQLAEAESAVERTQQIIAKSE
                     AHENNLQQQLSDLEQKIMATNIQLAEQEEHLQQALKKAFPEITEQKTKTTLVVIEQSL
                     DRRKSKMANARIELEEIRQQAEKLEQQLAVYKQQQTEKNNQLQQLQGEIKSLEQQLQD
                     TDSNCLEEEIRRLEKQLEEDSNQLAVEQKAGVQLLQDLHTLRTQLDLQHEQIEKIDEK
                     IEKEQERIAKKLESQSYFSTIEEICAFAQQQAQYKENQRTVTSYHEEQLVTADRLRQL
                     ENIQLTETFPDTEEISQQLEEIRRMIEIKQEKIYGLQEQKISNQKIYDECLSIYHTSQ
                     TKLDELTQLQQLSQTFNGENPKKTSLERYVLQVYLQEVLQVANDHLQRLTKNRYQFEL
                     ADTIGSYRGKTGLEINIYDDQAGMSRSAHTLSGGESFIAALSLALALADVIQTQAGGV
                     AIDALFIDEGFGSLDEEALEMAMEALETIESEGRMIGIISHVRELKERVLQQIRIDTE
                     GSGQSKIRYQLG"
     gene            40513..43707
                     /locus_tag="ACG8LA_001057"
     CDS             40513..43707
                     /locus_tag="ACG8LA_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SNF2 helicase associated domain-containing
                     protein"
                     /protein_id="HFQ0203371.1"
                     /translation="MKWSIPEKVIARGRQYLQEGRVLSVVPDQEENVWHAEVLGSELY
                     MVDLDGTAKEIDYCQCPYWEEHKYCKHTVAVELYLRSKNLSRIMKKDQPMLEPVKATS
                     EGEIIAKGFSRLKTQNNPQAVQPLIIEYQVETIETNQYHPELSILALYLRIGSLASPK
                     KTYIVKNIYDFLQAYTEKETYTVNKQYQFRLDKRAFQKEDQKILTHLAGSAQTHQLLG
                     TNGLQVKGKLDKRYLLLPVEQARFLLEQMNQTTRLHLQINEQNDQGIQFSDQNKPLSF
                     KVEKFGEDYLLQALNDFDFFFMHYQWGVIQGTFYSLTKYQQTVYQTWKQLIRRLEKPE
                     VVFKKKELPSLFKEIIPLLSEIGDVAIAPAVEEEVADIPVEFIFFFRKAKGKIQARVD
                     FVYGEVIYSTDPKHEVSTEQAFQVLRDTVEEKRVLDLFRMYRYQKNETGYERPLPSGE
                     ELYAFFRTELSVFRQFGEVRLGRKLRELYLDAHKHQPKIEVTETGSWLDIRFDVTGIE
                     EQEIDHVLQSLLRNDAFYTLENGQVLSFDSEEFQQTSQVLQQLRESIRTEEGTIHVPK
                     NQGLIIQNQLEKSNATFSESFQTMVQDLIHPERYQAQLPKGLNATMRDYQKQGFRWLK
                     MLGHYQFGGILADEMGLGKTLQTIAFLLSEKEERKSFSALIVAPASLIYNWQAEVRKF
                     APSLSIQVINGNKKEREELLAKDTDIRVTSYASLRQDLANYQSQKIDYLILDEAQMVK
                     NSSTKTAQALRELAVPQRFALSGTPIENNLEELWSLFATIMPGFFPTKTKFRELAAEE
                     IAQMIRPFILRRDKQTVLKDLPEKTEMNLYSALTEEQKTVYLAYLRQMREEITSMDSE
                     AFKKNRIGILAGLTRLRQICCDPRLFIEDYQGGSGKLEQVKDLLVAAKENKRRVLLFS
                     QFTGMLTILQEELAELGISTFYLRGSTKPQDRLSMVDAFNAGEKDVFLISLKAGGTGL
                     NLTGADTVILYDLWWNPAIEEQAAGRAHRIGQKNVVEVWRMISEGTIEERMDSLQQEK
                     RELFQKVIQGNEEQLTKLTEEDIRMILSVGEIEE"
     gene            complement(43853..44560)
                     /locus_tag="ACG8LA_001058"
     CDS             complement(43853..44560)
                     /locus_tag="ACG8LA_001058"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFQ0203372.1"
                     /translation="MIKSVVFDVDDTMYDQQQPFRNAVKRVVPLVSDADMHPLYIRFR
                     HHSDENFPKVMAGDWTLEYMRAHRISQSLKDLDYPHITEEDGLLFQKIYEEELDNICL
                     HEEVKKTLDFLKEKNVPLGIITNGPTDHQTKKLKQLQLNNWIPSRNMLISQATGFQKP
                     EKEIFQLAEKEFHMLPEETLYVGDNYDNDVLGAKSANWQALWFNHRERKIEQTPICDI
                     EISSFDQLLETMKTIFV"
BASE COUNT        14422 a         7973 c         9414 g        13125 t
ORIGIN      
        1 ttttgatgaa tcagttgttt cttcagttga agattctttt gttgaatcag ttgattttgt
       61 gtcagaactc tttgttgaag ctgtagtttc acttgagtct ttcgtacttg atgaagttgt
      121 tgtgaatgca ctcaacacat tttcaaaggc atcatctttg atttttacat ttgcatcttt
      181 taattcttca ccgattactt tagttgtgaa tgcattgtca cttagtttag tttcagtagc
      241 gatatctttt agttgatctt tgtatttatc catgtcattg cctttatttt ggtttttcac
      301 cattttgaca acgtagtatt ctgtcgcata agaagtagga tttgttgtag taataacatc
      361 ggagatctca ccgtctttca atttgaaagc tgcttctttt acttctgcag gaatagttgt
      421 tgtcgttgag tcgaatttaa ctttaccgcc atcttctttt gtctctgtat cagttgattt
      481 gtctttggct aatttagaga aatcatctcc atcatccgct gattttttca catcttttgc
      541 ttcatcttca cttgataatt tgatgatttg tgcttctact tctggatgga aagatttcca
      601 agcagttttc aaatcgtcat ctgtaatatc tacgtgagct ttcaagccag cttcaaaagc
      661 taaattgtta cgaatatatt ctttataagt atctttcgta tatccagcag cttctaattg
      721 tgattcaaaa gtatcaccta atgatttcgc ttgtttgtcg tattctgcat ccacttgctt
      781 atcggttact ttatcgccat atttgttatt gaatacttta taaatgatca tccgttgtac
      841 taaggattgg ttcgatgatt caagttttgc ttcatcatag aaatcagata cagtgatcgt
      901 tccgcctttc atcgttgcga tatctttatt agtatcgcct gaacaagctg ctagagttaa
      961 aacagccaac gcactagtag ctgccaaaat aattgatttt tttttcatta aaatttgcac
     1021 tcctgtaatt agttattatt tttatatatt aactatacca tatcccattt cctttaaaaa
     1081 cgttgtcgtg gtagtttcaa acaaaattca aaatttcatc acattcctag gaaatacgca
     1141 aacttttctc acttatatag ttaaatctgt tgagaaaata atcattatta tatttgttca
     1201 ggatactctg gcagatcagc ttttagtttt tctacttgtt cattgatttg tgtgatacgt
     1261 ggttcggctt ggaatttaaa atcttcgata tcttttttga ttgcttcttg gaaagcagga
     1321 atcacagatt cagctgtttc ttttgtttcg atcaatgcgc ttttaaaatg attcaggctg
     1381 ttatttaaat catttgtcag agttgttgct tcttccaatt cttcgatcag tttctttctt
     1441 gtttcattcc cgctcctggg cgccaataac agacctccga cagtgccagc agcagctcca
     1501 aataacagtc ctttgaaaaa gtttttaatc atcgcaggac acctgcttta cgattgtttc
     1561 ttgaatagct tttagttctt ccgatccata actatcttga tgattgacaa agtgaataga
     1621 aaaatcatcc tctttgctgt agcgagggac taaatggata tgtgaatgaa aaacagattg
     1681 ataggctagt tcacggttgt tattcaagat attaagacct ttcatttctg gaaaagcttt
     1741 ttccaatgct tgagcaatct taggcacacg cgaaaaaacc tctcctgcaa gttcgggatc
     1801 atattcaaaa atatctgcta catgacgttt aggcacaact aatgtgtgtc ctttcgttgc
     1861 ttgagagatg tctaaaaaag catagacctt gtcgtcttca tatattttat agcttgggat
     1921 ttcttgattg atgattttgc aaaaaataca gttttccata taaaacatcc tttctataaa
     1981 gaataaatac ttcagcttaa ctttaccata agttaaagct attgtaagga aaaaaacaaa
     2041 ataccgtcat tttcttcgtg gtataataaa taaaaataaa tggcggagga aaaagaatga
     2101 gtttaattat cgatcatgtc acaggggggt acggacatct ccctgtgtta aaagatatca
     2161 gtttcgatgt acagcctgga gagatagtag ggttgattgg actgaacgga gcagggaaaa
     2221 gtacgaccat caagcacatt atcggtctgc tggaagcttc aaaaggaacg atagaaatca
     2281 atcatctatc cttaaagaaa aatacggaag aatatcgcaa acaaattggg tatattccag
     2341 agactccttc tttatatgaa gaattgacat tgagagaaca tatcgaagtc actgcgatgg
     2401 cctacgatat acctatggat atagcaatga aaagagcaga aaagttgttg gagacttttc
     2461 ggttatctaa tcgtcttgac tggttcccag ctaatttttc aaagggaatg aaacagaaag
     2521 tgatgatctt atgcgccttt ttgatcgagc cttctttata tatcatcgac gaaccatttt
     2581 taggcttgga tccactagct atcaatgcat tgcttgaatt gatggtagaa atgaaaaaag
     2641 aaggagccgg tattttgatg tctacgcata ttttagctac tgcagaaaaa tattgtgatc
     2701 gttttgtggt cttacataac ggagagatac gagcagacgg ttctcttgag atgttgagaa
     2761 aagaatttca gctgccggat tcttctttgg acgaaatcta tattgcttta acaaaggagc
     2821 aggcacatga gtagtttttt tcaaaaacgt ttagcaagac atcaaaagaa aatgatgaaa
     2881 tatatgcgtt atgtattgaa cgatcatttt gttttagttt gtcttttctt gattggcggt
     2941 gtgggattat attattctaa ttggttgaaa accctgcagc caccgtttgc aattggaggg
     3001 ctcataatct ctgtattttg gatgctctgt ttattcgtgg gtaagatggc tacttttgca
     3061 gaggcagcag atattgtttt tttacttcct aaagaaaaag aaatgcaaac ctatttggaa
     3121 cgagcttttc gctattcttg catttttccg ttgatctttt tgatattggc atgcggattg
     3181 gccatgccat tagtggtggt tagtacggag caatcctttt cgatgttttt cgtctatctg
     3241 atcatattat ggagtttgaa attcagtcat ctgcaaatca agagagcaga attgtttcga
     3301 ctagatcaac aagttattcg ttattggaaa ttaggctggt ttttttcttc tctgatcttt
     3361 ttgtttctat cattttattg gctaatatgg gcaggaatag caggtgcatt agtacaggca
     3421 agtctatatt actggttttt gtggaagcaa caagaaaaag gattggattg ggagaaaatg
     3481 gtgcatgtag aagaacatag gttgcatcag atctatcaat ttatcaattt attcacagat
     3541 gttcctgaaa ttacggcaaa gatcaaaaga agacgctatt tggatcctat attgactcat
     3601 attaaaagag aatcaaaaaa cacttatctt tacttgtttg caagaagatt ggcaagaggt
     3661 tctgatttta gtggtcttta tttccgatta gtaattatag gtgggttatt gattgccgga
     3721 gtagtcgact tttattttag tctgattatc ggtttcttat ttttatattt gatcggtttc
     3781 caactgttac ctttagcgaa ccagttccgc tatatggttc tcgttcagct ttatccaatc
     3841 cataagaatc agaagaagca ggcgattcag tatctactca catgggtatt aattatcgcg
     3901 tcggttattt ttggtttgat tgctgcagtc gtattagatg ggcagcagcg atgggttccg
     3961 ctagcggctt atttgattgt tactatgctc tttgttaaac tatatgtacc aactcgtttg
     4021 aagaagatgt cagactgaaa acaaagctgt gtagggtaaa aatgagaatg aaaaatagag
     4081 cgttgacagt aagaatgctg ttcgttctat tttttttgag aaaagctggt tttttgaatg
     4141 gcaattaaat gaaaaagaac gtatatgtgc ttgacgtgta gtgttcaggc gactagaata
     4201 ataagtactg caaaacaaag agtaagagga cgggagaatg catgatggag tttcagttag
     4261 accaagagtg gcggttacgt cccatcaaag gcgacacagg aaaaacatac ataggcatgc
     4321 gtgatgagga caaagtcttt attaaacgaa acacgactcc gatgttggct gctctttcaa
     4381 gggaaggaat tacaccaaaa cttgtttgga caaaacgaac ggggaatggc gatactttga
     4441 cagcacaaga gtggctggaa ggtcgcttgc tgactcctaa tgagattggt caaagaaacg
     4501 acgtgattga tgttttgtac catttacatc attcaaattc tcttaaaacc atgctgaccc
     4561 gtatcggtgg tcgtgtcatg acgccggaga agatgctgca aaaatatgaa aaagaattac
     4621 cggaagaact ccagaaaaat caatttctgc aaattgtcca tcgttttctt cgtgagcaga
     4681 tcccgtcaat agataaggaa aacttatcag tagtacacgg agatgtaaac catcgtaatt
     4741 ggttagtatg taaaaattat ttatatctag tcgattggga ttcaatcatg tttgcagacc
     4801 ctgcggtgga tattgcaacg attttaggaa attatgtgcc actgtctagc tggaatcagt
     4861 ggctgatcag ttatggcata cgcccgactg acgaaatgct tgaaaaattt cattggtatg
     4921 cggccatgaa tttgctccaa gaaatcacca gatattgcaa acgtgaagat catcgacgga
     4981 tgaacgaaga aattttacaa ttaaaacgaa ttttcagtgg ctgaggtttg gcccaaactc
     5041 tgcggagatt tggccagacc tttttaatta gaggaaagga atggagataa ataatgcgtg
     5101 tccgaaatcg tccgggagca gcggaaatgt tagcggctca cccgaatttt gtaattagtg
     5161 atccaacatt gtggaaggga aaatggaatg aattgtttga aaacgatcat ccaatccaca
     5221 ttgagattgg tatggggaaa ggccagttca tcactggaat ggcaaaagcc catcctgaaa
     5281 tcaattatat tggagtagaa atgcaggtca gtgttgtttc gattgcacta gacaagttga
     5341 tcgaacaacc gcttcctaac ctgaaacttc tacatgtgga tggatcagcg ttgacagagt
     5401 atttcgctga cagcgaagta gatcaaatct atctgaattt ttccgatcca tggccaaaaa
     5461 aacgtcatga aaaacggcga ttgacatata agacttttct tgctgtagat gaacagattc
     5521 ttcgtccaaa tggagaaatc catttcaaaa cagataatca aggattgttt gagtattctc
     5581 tggcaagttt ttctcaatat ggcatgatcc tcaaacaggt atggttagat ttacatcaaa
     5641 gtcaatttga aggcaatatt atgacggagt atgaagaaaa attttcttca aaaggtcaac
     5701 gtatttatcg agtagaagct caatttcaag ataagaccaa aaagaaaagt ctgtgaaact
     5761 aactttctgc tttcataaaa acattaatat ccataaataa atcccagaaa atgaacatta
     5821 cagatgtaat gtattttctg ggatttattt gatttaaaat gtatttattt catcggtttt
     5881 tccacaaggt ggaatcaatt ggaagcgaga aaatgaaaat aatcctttgt cggtgatctt
     5941 caattcgggt atgacagata atgttaagaa agaaagtgtc aaaaaaggat caaaggtttt
     6001 agctgctcct agttgatgtg ctttagttat taattcattc aactgttcat agacgatcga
     6061 aaaaggttcc tgtgtcatga ttccgcctat aggaagagaa acacaagcta tttcctgctg
     6121 attgttgaca acggtcatcc cgccaccttt ttgaatcaaa agattagcag catacagcat
     6181 atcctcgtcg tttgtcccaa cgacaactag attatgcgag tcatgggcaa tcgttgtcgc
     6241 tatcgctcct tgtttcagct gaaatccttt cactatgcct aatccaatgt ttcccgtttg
     6301 atggtgacgc tcgatcaccg caatctttaa ttggtctttt tcgattgaag gaatgaatcg
     6361 ttcgccttgt cggtccactt tttctaccaa atctttagtc actagactat tcgggataat
     6421 ttcgatcaca tgggcttgtg aagaagaaag aagcagctct aacgaatgtg gatttaatgg
     6481 ttgagcgttt agttttggca gacaacacgt atatgaattt gaatgatcag caaataaatg
     6541 gtcttggagt tgcccagatt gaacaactaa tgttccctta tagaaaactt catgaattgg
     6601 cagcttggta agatcgtctg ttaagaagaa atcagcttga tacccagggg caatcgcacc
     6661 tagtgttttc aaatcaaaac attctgctgc attcaatgtt gccatctgaa tggcttgtaa
     6721 tggatcgatt ccaagtgcaa tagcttgacg gacgatatga tcgattgatc cttcttttac
     6781 taaatcattg atcagtttat catcggtgac aaagaagcat cttcttgaat tttcaggtgt
     6841 gatcgccggt agtagcgatg ccagatcttt tgcaacggtc ccttctcgaa ccattaaata
     6901 cataccaaga tccaaacgtt ctttagcttc ttttgcagtt gtagcttcat gatccgtccg
     6961 aatacctgct gcaggataaa catttaactc ttccatgccg ataccagctg catgcccgtc
     7021 aatttttttc ttatgctggt gcatcaattg gatcttttct aggatgtctg tttcattatt
     7081 tgctactgct tgatagttca tgacttcagc taagcctaaa acttcgggtt tttgtaaaaa
     7141 aggggctaat ttttttgcat ttaaatttgc accattggtc tcaaaagggg ttacaggtac
     7201 acaagaaggt agcataaaaa agatattcat gagtgtttgt cttgcatctt ctatcataaa
     7261 ctcaagacct gtactcccag caatgtttcc tatttcatgg ggatctgtca ctacagtagt
     7321 aactccatga agcaaggata cttttgaaaa ttcgcttggt gataaaagtg agctttcgat
     7381 atgcacatgg ccatcgatga atcctggcac tagatattgc ccattagcat tatgtacgct
     7441 ttttccttcg tattcaccga ttcctacgat cattccttcg cagattgcta catctttttc
     7501 catgatttct ttcgtaaaga cgttgacgat cttagcatgc ttgatcacta ggtcagcagg
     7561 ctttttttta cttgctactt cgatatattt ccttaatgtt gtttccaatg gagtgcctcc
     7621 caagataaat ttttataagt ataacataaa ttcggttttt gccaatattt ttttgtaaat
     7681 tcattttatt tgaaacaaaa agatcaaaaa gacgtatgtt ttttgtggag gggagaataa
     7741 tggaaataaa acgattatcg gatcaaatga taagtgaaag ttttgccaaa catgcccaag
     7801 acgtatatat attgccagct tcagaagtat tttacatcta ttttcgctat ggaaaaaaac
     7861 gaacattctg gaagaaagtc tcttcggcag atggacagca actgatctca agatttaagt
     7921 atttgggaca gatggatatc ggagaaaaaa gaaaagctca gttaggtgca tttacttatt
     7981 ctttagaaaa acaggaagtt cgtctgcggt tgtcttctgt aggagattac cttcaacgag
     8041 agagtttagt gattcggcta ttatacggta cttttgaaac accccatcgt tgctttagtt
     8101 ctcgagattt tgcaactatt ttacagaaaa ccgtcagacg tggattatac cttttcagcg
     8161 gaccagtcgg atcaggcaag acttctctaa tgtatcggtt ggctttggaa gaaaaattgc
     8221 aagtgattac tatcgaagat cctgtagaga tagaagaacc gttttttctg cagctacaga
     8281 tcaatccgaa aatagcacag acttatgata cacttttgag actcgcatta cggcatcgtc
     8341 cagacttgct aatcattggc gagataagag atgaatcaac tgcacatgct gcggtaagag
     8401 cagcactaac agggcaccgg gtttttgcaa ccgtacatgc acgcaatctt gaaggtacat
     8461 tggtcagaat ccatgaactg acaaagaaaa aagaagagct atctgaatgt ttagctggtg
     8521 tcatttatca agaacttttg gaagatgcca atcaccatcc ttctgtttta tggagttatc
     8581 aatttatgga ggaagaatca gtaaaaaaat catgggagga aagttatgaa gaagctcagg
     8641 aaaatatttg gcagtcagaa ctattctaaa ggattaacaa gaagccagca aaaccagttt
     8701 gcacaaacca tgggagaact gcttttatct ggttttagtc tgcaagaatc cctttattta
     8761 ttactcacga tccgttcgtt tccacctgtt attttggcaa atatccaaca tcagctaaag
     8821 gaagggcaag cgtttagtga ggtactttcg caaataggat atggagcaga gcaactggta
     8881 cagatcgagt tagctgaacg tcatgggaat ctgccgacaa ctttgttgga aattgccaaa
     8941 cagtttcggc ttgttgaagg atttcgcaat gatttgaaaa agctgcttgc atatccgatg
     9001 ctattgctca cctttttgct aggtatcttg tttagtatgc ggttgttcgt tttgcctcag
     9061 cttattggtt caggaatggt catgcaagag cattggggta ttcagctgat acaagtcttt
     9121 cattggtatg ttctactatt catcctagcg gttactctat tggctttact agtaaggtat
     9181 cgtctgatga agttgtctcc tgttgatcag agtgaatgga taagcagaca attattgatt
     9241 ggaccgatat attccttgta tcaatcggct tatttgtcac tagagattgg aaagcttttt
     9301 catgaaggtt tcgaattaag gcaaatcata gtctgcttaa aggaaacgaa acaagaaagt
     9361 ctgattcagc atcttgcctc taagttgatt caaggattgg aggcaggtat gtcattggct
     9421 gagcagttcc agaattatcg ttttctatca gaagaattca gtaaaattgt tttacaggga
     9481 gaggcaaagg gaagtttagg taaagaactg attttttaca gcgaatggac aagaaaacag
     9541 cttttcaaac gtcttcatca ctggatgcat tttattcagc caatcatttt tttgggcgta
     9601 gcggctttga ttttattagt ttatgccgct gttttattac ctgtttacgg aagcatagag
     9661 gaggttttgc catgaaaaag agaaaaatat cttattatag cggttttaca ttgatcgaaa
     9721 tgctaatcgt cttactgatc atcagtgtat tagtgttgtt gttcgtccct aatttgtcgc
     9781 gttataggaa tcatgtagac caagaaagtc gtgaagcgat catccagttg gtagacacac
     9841 aaaaagagct ctatgcgctt caaaataatg gaagagttcc tactgtggag gaattgttga
     9901 atgaaggcta tatcaaacga gaacatgcag aaatctatca gcggccttga aggtaaggtt
     9961 ttagcatcag gatatacgtt gtttgaatca ctcttactga ttttattact tacaacgatc
    10021 ctttcttttc cagttctcgc attttctgca tggaagaatg aattggcagt ctatcaattt
    10081 ttcggccaat ttgaaaaacg aatctattct acgcaaaaaa tcgctattgt gaatcagatc
    10141 caaacaggct tttattggaa tagtgaagag aatcaaatca tttttcatgt tccgaatcca
    10201 gataaaataa attgggaagt attagatatt cctgatgaga ttaccttgaa acgccatgct
    10261 tctattactt ttgctgctag aaccgggaat gaaagttcac taaaagctta tcaattttat
    10321 tgggaagaaa aagagcggac gattacgtat caattccaga tagggagtgg tcgctataca
    10381 aaaagaattg aataaaacag gatttgtttt gttggagtcc cttacagcgc ttatgatcgc
    10441 ttctgtctgt gtctacttag tgagctttgg ccagctgttt ttgcttcagg cagaaaagaa
    10501 aagtggggag gaactgctat ttattcgaat gatttatgaa gatatcaaga cgcagcggat
    10561 gtatcacaaa agaccagagc gaagggaaga aatgatccca tacgatatcc aaattgtcga
    10621 taataatgga gtaatcgaaa aagtgtttgt caatatggag aaagaagcga tcagtattga
    10681 aaaaacaagt aattccagca tttacgctga ttgaatgtct aattggactg atgatattga
    10741 gcagtctatt gctcacattc aatcttttga ttcagcaaac catccaagta agtgaatttt
    10801 tgcagcgtaa agatcaaaaa gagtggctaa tatttttagc acaattagaa gaagaactca
    10861 agagcagtca caatgtctct gtgaaaaatc agcaactgca ctacacgatc gaggataaac
    10921 agtatatcat cgaaagatat caggcaatga tacgtaaaag aagaacttcc ggcggacatc
    10981 aacctatgtt aacaagtatc actgagcttc aattattgga aaaagaacac acaatttctt
    11041 tttatgtaca ctttgaaaat ggagaagatg gatatgccat atggacaaaa aacgatcagt
    11101 agaaaatgtt ataagggctc tattttattt tctgtcttgc ttttatttct tttatgtacg
    11161 tttttattga tggcagcatt agaaagctac cgtttgtcaa tggatcttaa tatacgaatc
    11221 aaaaattatt atatagcaaa aataatgaag cagatggctt tatcggaaca gtctacgctt
    11281 gccgaaagtt cggaaggagt tttttactac acaactggat ctgtaacata tcagtgggta
    11341 caacagtccc tattcttaga ggtggaagtc tcaccgttta tctttcggtt cacagaagaa
    11401 gtaaaaaatg atacagatac tagtacagaa tgatggaatg ttcgtgaaaa cgccctcttt
    11461 tctgttataa cactgttttt aataaaaaaa tgtttgccgt ttcacaaata aaaaacagtg
    11521 aaaacgattg aaattttgtc aattgttcga tagaattaaa caggtgaaaa aattgttata
    11581 atatatctag aaatgaggtg caccatgtta ccagaaaaaa tggaacaagg gtttaatcaa
    11641 aacctggaag ctattcagct tttacagaat gcattgggaa cttccttttt agaagcctat
    11701 gtcgaaaatg cagaaaattt aatagatgat tatcaagtac gtgtggtgga tggagtgccg
    11761 acaaaagaga caacgcaacg gatcacagct ctttatgaag agttgaagaa actttctttc
    11821 gagccagaag aatggcgcag actgtctcaa ttacttttat tgaagggcag ccagacagaa
    11881 catttgcagg cgaaccatca actcactcct gatagtatcg gttttttatt tgtttttctt
    11941 attgaacaac tatacacaaa taaaaaagca ccggttaaga ttctggatat tgcggcagga
    12001 atgggcaact tgttattaac agttctttta aacctatcga atgcggggta ccaaacagaa
    12061 ggaattggtg tggatattga tgatacattg ttggctgtcg cagcttctac aagtgatttg
    12121 acacaagcaa atgttcaata ctttcatcaa gacgggttgc aggaattatt aatagatcct
    12181 gtcgattttg caatcagcga tttgccaatc ggttattatc cgaatgacga aaaagcaaaa
    12241 gagtttttaa caagtaccga agaaggccat agttatgcac atcatttatt gctagagcaa
    12301 tcaatgaaat atgtgaagcc ggatggtttt ggtttgtttt tgatgccgag tggattttta
    12361 gaaacggatc aaagtgaaga aatcaaaaaa tggtttaaag aagaaggtta tcttcaagga
    12421 atgattcaat tgccagatga attgttccgt aataaacaat cgcaaaaaag tattttgatc
    12481 ttacagaaaa aaggaccaca agcacaacaa gtaaaagaag tcttgcttgt gaaacttgct
    12541 tcattaaaag aaccagagaa ggtgacggaa tttttcaacg agtttaaaaa ctggaaatca
    12601 tctgctctgt aatcattcaa cgagaaggag agtcatatgt ctaaaacaat tgcaatcaat
    12661 gctgggagtt caagtttgaa atggcaatta tatcaaatgc cagaagaaac cgtagttgcg
    12721 aaagggatcg tcgaacgtat cggtttacaa gattctattt ttaccatcaa gtacggcgat
    12781 aatcaaaaat tcgaacaaat catggatatc gaaaaccacg aagtagcagt aaaaatgctg
    12841 ttagatcagt tgattgaact gcaaatttta agctcttatg atgaaatcac cggagtaggg
    12901 caccgtgttg ttcacggagg agaaacttat ggggattcag tagtgatcga tgagaaagta
    12961 atggaccgca ttgctgaatt agcagaattt gctcctttgc ataatcctgc aaacttaatg
    13021 gggatcaaag cgtttaaaaa gattttacct gacattttga gtgtggctgt attcgataca
    13081 tctttccact caacaatgcc aaagcaaaat tatttatata gcttaccggt gtcttattat
    13141 gaagatttca aagtaagaaa atatggcttc catggcacaa gtcatcgtta tgtgtcggaa
    13201 cgtgcggcaa aattattgaa caaaccgatc gaagaactaa aaatcatcac ttgccactta
    13261 ggaaatggtg tatcgatcac agcagtcgat ggaggtaaat ccatggatac ttctatggga
    13321 ttcacaccat tagctggggt gacaatgggt acacgttcag gtgatatcga tccagctgtt
    13381 ctcccatatt taatggaaaa attagagatt gatattgatg aaatgatcaa tgttttgaac
    13441 aagaaatctg gtctgctagg cctaacagga ttgtctagtg atatgcgtga tcttgaaaag
    13501 aactatgaaa aagaacatat tcgtttagct tatgacattt tcgtggaccg catccgaaaa
    13561 tacatcggcg gttatgtgac aacgatgaat ggtgttgatg caattgtctt tactgctggt
    13621 atcggcgaga atgacggaca tgtacgtagt gaaatcatca aaggtatgtc ttggtttggt
    13681 tgtgaaatcg atccagcgtt gaatgaattg cgtggtgaag aagtagatat ctctacaaaa
    13741 gaatcaaaag taagagtatt agtgatccca acagatgagg aactaatgat tgcccgtgat
    13801 gtggagcgtc tgcgcggcta agccaaagca ttcgttagga taaaagatga aacgcatgca
    13861 agagggaatt cttgcatgtg ttttttttgc ggagaagacc gcaaaatggt aatttaactt
    13921 caatttccct tcttttttac aggatcttct tagggaattt tgcttggaaa agtggtcaaa
    13981 agggaaaaga ctggcatttt atttattgat tttcaggaaa atcccaatat tttattttca
    14041 ttcatcttta taagggacat tacatatgta aaaagaaaaa acatttttag atcagcctcg
    14101 tgggctgtcg actttattct tcgctttatg tttagctaga aaaccgatcc gaaacattca
    14161 ttgatcgaat aataaaaact tgattttcca cctgtacttt gcctgaatcg tgaaagcaca
    14221 ggtatgaaaa tcaagttttt tgttgcgaaa aaacgtccta gtcaatcagt tggccgagcg
    14281 gctggcggct gatctgctcc tgatcaataa cgagtgcttc ttggaagtgt tgctgcaaaa
    14341 agtagcggtc atggctgact gctaggagcg ttccttgata gtcttgcagc atttcttcaa
    14401 tttcttctcg agcatagctg tcgaggtgat tggttggttc atccaaaatc aggacgttga
    14461 ttttttctaa aaagagtttc agcaacgcca aacggatttt ttcaccaccg gataaatctt
    14521 tgatccgttt acccacatcg ctttgataaa agccactttt ggctaattgc cgtcgagcga
    14581 cttcttcgtt tccagtcaat gtgatggcgt aagccagcaa acggctatcg ggatcggcaa
    14641 actgcagctg ctgcggcaaa taaccgattt gcaagctact acctaatttg atggtgccac
    14701 cgtaaggctt ttcctcaccg agtaataatt tgagtaaggt tgattttcct gcaccattgt
    14761 cgccgatgat ggctaaatga tctccacgat agactgcaaa actgctgtct ttgaatagta
    14821 cttgatcagc gtactgctgg tgcaagtttt gaatgatgaa aacttctttg ccagattttc
    14881 caccattaga caagctttgc agccgatttt tcgggggagg tggcggtttg acgagtgtca
    14941 gtttcgccag gcggcgttcc agttctttgg cttttttgaa gaaggactca ttgtctcctt
    15001 catgtgccca ctgacgaaaa cgacgaatca tgactttcaa ccgctggact tctttttgct
    15061 gcagttcgta attttttgtc agctcagcca agcgagcttc tttcaagact cgaaaacggc
    15121 tgtagtttcc gggatactca atcaatgcac cttcttccag ttcccatgtt tttgtggtga
    15181 cttgatcgag aaattgccga tcatgagaaa cgaccagaac cgattttttt gtattctgta
    15241 aatagttttc caaccagcga atactgttaa gatctaaatg attggtcggt tcatcgagta
    15301 aaagtaaatc ggcatcggct gctaaaattt tggctaaagc gactttaact cgttcgcctc
    15361 cgctaagttc tgttaaccgt gcttcctgac ggtgtggaat ccctaagcct tgcaagatcg
    15421 ctgcaatccg gtcttctaat acgtaaccgc ctagttcttc aaagcgatgc tgcagctcac
    15481 cgtaacgggc cagacacttc tctaagtttg tatctggttc tgtcatcaat gcttcgtagc
    15541 gactcatttg ctgtttgagg tcctgtatct cagcggcaga atggagcaag tagtggttga
    15601 cggtcgcttc ggaaactgta agttcttgtt cgaccgtccc gatctttaag ccttttttgc
    15661 gactgataac accgctgtcg acaccttctc tgccggtcaa gatttgtaaa aaggttgatt
    15721 tgccagttcc gttgataccg actaagacaa ttttttcacc agcttcaatt tgacaggata
    15781 aatcctcaaa taatggattc ccgccgattg tttttttaat agaaattgct tgtatgatca
    15841 tgatctctct ccttgagacc actcaaaaag gccatggtta tccatggcct gtgttattta
    15901 aactcagatt atcatgagaa aaataccttg agatggccat tgattttacg tgaattcaac
    15961 tgttttggac aaacttgtcc cgtcaacagc aactgtaaaa ccaattgcat ggctaaatgc
    16021 gatatggtat cgttggtaat tttcattact tgttatttta gtcatgcgca tcatagtatt
    16081 ttccctcctt cgtgtagttg tcttttccag tgtacctgaa agtgtcagaa agttcaacta
    16141 gcgctgacat ttacttaata tttatcgatg tgtaattctg tcagagagct ttttttatct
    16201 gactgagggt aatgtctcgt ggaccacatc attgtattct gagctaaacc agcgttcagg
    16261 cgaaatcata tggtgtttga taaaaaactt tgtctacatg acttcctttt gccatttgct
    16321 taataccgtt gcattaaaca gctcttctct ttggaaatct caccaacatc gcgttcagga
    16381 gtatcgttgt ggttgcaatg gcaagcggta gcctttcatc aattcttgaa tgatttaccg
    16441 aatgtagcac ttgccttctc gcggtacccg aacccgaaat aaaattttag tttggcgata
    16501 aaatcggtat ccgccatcga tacttcatat tttttcgtat cagattcatc ggaaacttcc
    16561 acattgacga accaataagc tttggcatgc ttaggtcgtt ttaaaccaca ccagggcgac
    16621 taatcgccct ggtgttcact tttttttatt ttacttgaac tcattgactg ttttcccttt
    16681 attttaaaca ttataaagac cgatgagtgc ttgccgcgtc ttttgttttt atcacggttt
    16741 tttgtgcaaa aaaacctgcc gatagttggc aggtcgtcta cgtgttaagc tttggtgtgg
    16801 tctttagctg gcaattggtt ttctaaatca gttcggacaa caagcacatc gcaagctgcg
    16861 tttctaataa catattcaga aacagaacca ataaataaac gttctacagc attcaatcct
    16921 gtggctccta acataatcaa atctacttga ttatcttctg ggatttctct ggcaataatt
    16981 tgttttggtg agccatattc tacgacagag gttacattat tcaagccagc tttcttcgca
    17041 ttgctttcat aatctgccaa tgtttgcttt gccatttcag tagcttgttc tgcaagcatt
    17101 ccatcaaagg atgaaacggt ttggaaagaa cgtgtgtcaa tgacatgtgc taatagaagt
    17161 tctccgttat ttcggatagc tacattgacc gcctttttaa aagctaattc agcttcatca
    17221 gaaccatcta cggcaaccat gatttttttg tattgttgta acataagcat tcactcctca
    17281 agtcaatcgt attgtactct tttattgtag aacactttag ggaaaaagag aattatttac
    17341 tgctttggtt cagcaatttt ttttgcaaat cggatactga aggtggcaga aacaataatt
    17401 acgatcagta aaaagaccaa ggcaataaag cgttgattga aaaaagctgt taaaataccc
    17461 attacgccta aaacagcata tgcagctccg taaaattgta ggaatccttg atttttatca
    17521 tttttgttga tcaatacaaa aaagatatcc tgtttattaa ataaataata gctaacgaat
    17581 aataatacta aagtggcgat aatcattaaa atcctaatca tgaacaaatc ctccaaaata
    17641 agcaacaaat agaaaaagca atttgccaag agcaaattgc tttattcttt aaaagatggt
    17701 aatctccgtt aatgccgttg tttgtcctgt agtattgatc ccgcgaattc aagcaggtgg
    17761 gtcccatggt cgtagcttcg aactaccaaa tgataaggca tgttaccagc agtgacacaa
    17821 gacgggtccc aagatatcaa taaaaatgtt cggtcaacac acaaagagga caattcgaac
    17881 atcacagatt tcccacctct atagtagcat atgaatttaa aaagagcaat gagagagctc
    17941 gcagaaacag aaccgttttc ttgtctagtt ttttggagga tgctttttcc actcttttat
    18001 acggtaatac tgttgaccca gagcctgttc atatttccct gtatcttttg gctgataata
    18061 ctgagcattc ttcagtttat ctggtaaata ttgctgattg acccaagcct gatcaaaatg
    18121 atgaggatac tgataaccca cgccacggtt gagtgatttc gcacctttgt aatggctatc
    18181 tctcaaatga tcaggaacat ctccagcttt gccctctcga atatcagcaa gtgctgcatc
    18241 taatgccatg taggcagaat tggattttgg cgacaagcaa agatcgacga cgacgtctgc
    18301 tagtgggata cgtgcctcag gcaatcccaa tttttcagca gctaatacag cgttcactgt
    18361 acgagccgca gcagcaggat tacctaaacc tatatcttca taaccgataa ccatcagacg
    18421 ccggcaaata cttgccagat cacctgcctc aactaaacgg gcgagataat gaagtgcagc
    18481 atccacatca cttccacgaa tcgatttttg aaaagccgaa ataacgtcat aatgagcatc
    18541 tccatttttg tcatgggtaa gagcttttct ttggacacat tcttcaatga tcgacagtgt
    18601 aagatgaatc cttccttctt tatctgaagg agtcgatagt gtagccagtt ccagcccatt
    18661 caatgcactc cgcaaatcgc cgttcgttgc acgcgaaagg tgaagaagag catcttcgtc
    18721 taactggatt gcttgttgtc caaggccgcg ttctttatcc cttaaagcat gttcgactgc
    18781 caactggatg tcttgttctg ttaatggttt gacttcaaag atctgtgtac ggctgcggat
    18841 cgctggattg atggtaatat aaggattctc agtagtcgct ccgatcaaga tgattcggcc
    18901 actttctaaa tgaggaagca gaaaatcctg ttttgtttta tctaatcggt gtacttcatc
    18961 caataagagg atcactgtac cactcatttt tgcttcttcc gctacaactt gtagatcctt
    19021 ttttgaatct gtagcggcgt ttagcatgcg aaatgcataa ttagtagagc cggcgatcgc
    19081 acttgcgata ctcgtttttc cagtaccagg aggtccatat agaatcatgg aagagagcat
    19141 gcgagcatcg accatgcggc gtatgatttt tccttccccg actagatgct gctgaccaac
    19201 gacttcatcg atcgttcgag gtctcatgcg ataagccaat ggctgttgca taggattttc
    19261 ctccttcttg tttttacgtc ccttaattat atcatattta gcaagatgcc tagaaagaac
    19321 agccttctgt tgttttgttt tcatagctta tccaactaat attgtgtatg ataaagtagg
    19381 tgagaaaaat gacggataaa caaaagatag atgaattttt ttggaataaa acgacgccag
    19441 aagtggcacg ggatttattg gggatgtatt tggagcatga cacaccagaa ggaagattag
    19501 ctggatatat tgtagacgcg gaagcatacc taggtccaga agacgaggcc gcccatagct
    19561 atggtttaag aagaacaccg cgtgtgcggg caatgtatga aaaaccaggt acgatctacc
    19621 tttacacgat gcatactcat cggattttga acatcattac tcagccagaa gggattcctc
    19681 aaggagtaat gatacgtgca atcgaacccg ccgcaatgat tgatcaaatg agtaaaaatc
    19741 gtggcggaaa aactggtcca gatatcagca acggtccggg aaaattagtg gaagcattag
    19801 caattcctca agaactttat ggtcagtcta tagcagatag ttcgttacgc ttagtttttg
    19861 agaaaaaaaa gacaccaaaa aagatcaatg ctttgcctag aatcggtatc ccaaacaaag
    19921 gtgtatggac agaaaagccg ttgcgttttg ttgtgtcggg aaatccttat atctctttac
    19981 aaagaaaaaa ccaaatcgag aaagattggg gttggaggaa agaaaatgaa aaagaaggat
    20041 ctattaacat atttagatga aataattgaa aaacaagtga cagactatga tgtagcttta
    20101 gattgggata caaaaaatca tacgatcgag atcgttgttc gcttgtttgc agaaaataaa
    20161 gcacaatttg agattgatga tgcagaaggg atcgtttcgc aagaaccaat tatcgaattt
    20221 gaagacggcg tacttctttt taatcctcag aaatctgttt ttgatgaacg caattatcta
    20281 gcagtaatcc cttatgaagg aaaaaaaggg ttggcaaaat cagtagctga ttctttagtg
    20341 gaatatctaa atgaagtatt agctcaaggg caaagcgatt tgcttgattt tttggatgaa
    20401 gacgatgacg aagctgtatt cgagcttcac tgggataatc agcaactagc agaattagta
    20461 gaagtaaaac agcaaaatga agcagatact tatttaccgt acccaagtta ttaaggagtg
    20521 acagatatga aatggaatga agtaaaagta gaaactgaaa gtgaagcagt cgaagcagtt
    20581 gctaatattt tgatggaggc aggggcgagt ggtgtcgcga ttgaagattc tttagatgtt
    20641 gaacattttc agtcggatca atatggtgag attttagata aaaatgattt tacatcgctg
    20701 aaagaaggcg cactagtcat ggcttatttt ccggaaacga ctttcttacc ggaaatcttg
    20761 ccttttatca aagatcgtat cacacaatta cctgagtttg gtctagctat tggaaaaaat
    20821 aaagtaacag ttagtgaagt agaggaaagc aactgggcaa cagcctggaa gaaatactat
    20881 catccggtgc gtattacgcg aatgctgacg gttgcgccaa gctgggaaaa ctaccagaca
    20941 gaagatcctc tagaaaaaat tatcacacta gatcctggta tggcatttgg cacaggcact
    21001 catcccacga cttccttgac attgacagca ctagaaacag tcttgcgtgg tggtgaaaca
    21061 ttgctagatg tgggaactgg gtcgggcgtg ctaagtattg cagcaaaata tcttggtgca
    21121 aaagatgtct atgcctttga tttagacgaa gtagccgttc gttcggcgaa agaaaatatg
    21181 gatatgaatg aaatagccaa agatgtccat gtatcagcta acgatctttt gacaggaatc
    21241 gagattgaaa gtgatgtaat cgttgcgaac attttagcag atatcatctt attgatgatc
    21301 ccagatgctt ggcgtttact gaagcaaaca ggcacgctga tcgtttcagg aatcattgaa
    21361 gagaagaagc aaatggttct ggatgccatg ttagaacaag ggtttatcgt ggatcaaatt
    21421 ttccagcaaa aagactggta tgcaattatt ttgaaaaaac cagaggtgga atagatgcag
    21481 cggtattttt taaaagaatc atatgaatca aaagactatt ttgttttaga aggggaaaac
    21541 tatcaccaca ttgtacgggt tatgaggatg gaacccgagg atgaagtttt tttggcattc
    21601 aatgatcaaa tagccattgt tgcagaaatc acggagatta ctgaagaggc tgtttatctg
    21661 aaagaaatta aaaaagaaga aaatcaaaag gaactgccaa gttcgattac catagcgagt
    21721 ggctatccta aaggggaaaa gctggattgg atcgttcaga aatccactga attaggagcg
    21781 caagcttttc ttggtttccc ggcatcagcc tctgtcgtta aatgggatgc aaaaaaacgt
    21841 atgaaacgac aacaacggct tgaaaagatt gctcaagagg cagcggaaca atcccatcgg
    21901 cagatcgtgc catcagtaga gttattggaa acgaaacaag atttatttga gcggctagat
    21961 gattatgacg tggtcttggt tgcttatgag gaatcagcaa agcaaggcga aaaatcaaat
    22021 gcagccaaaa ttcttagtga aacaaaacca gatagtcgaa tcttagctgt ctttggacca
    22081 gaaggtggat tatcccgcga tgaagtcgat tattttgtag aacacaaagg gatactttgt
    22141 ggattaggac caagaatcct tcgtacagaa acagcacctc tttatttatt aagtgctgct
    22201 agctatcaat gggaattaat gaatccttct ttcagctaac gttcttcatt aataaaagag
    22261 tatcgacaga aagaattgaa aaaatagtca acaatttgta taatagaaac aattatttat
    22321 acaatggata cgaaaaatcg tttgaaaaag cttttaaaaa gcgaacattt ccgtaaaaaa
    22381 acgtataact gcacggattt tgggacaatt atcaaacaga tatttgtccc gattcccgtt
    22441 ttaccgaaaa aagaaagggg gatcgattcc tgtgacaaaa gaagaaattt taacgggacc
    22501 cggtgtcata aagctcgtta gtcaatacat gggtcccgaa catgtagcat ttgttgagaa
    22561 agcatgcgaa tacgcgactg ctgcacatga cggacagttt agaaaatcag gcgaacccta
    22621 cattattcat cctatccaag tcgcaggtat attagcagat ttaaaaatgg atccccatac
    22681 agtggctaca ggcttcttac atgatgttgt tgaagataca gaaatcactt tagaagatct
    22741 gagagaagaa tttggcgatg acgttgctat gttagtggac ggcgtaacca aattagggaa
    22801 aataaaatat aaatcccacg aagagcagct agcagaaaac caccgaaaga tgctgctagc
    22861 aatggctcaa gatttacgag ttatcatggt caaattagct gatagactac ataacatgcg
    22921 tacgttgaag cacctgcgag aagataagca aagaaggatc gctcaggaaa ctttagaaat
    22981 ctatgcgcct cttgcacatc gtctagggat cagccggatc aaatgggaat tagaagatac
    23041 agcacttcgt tatctaaatc caaaacagta ttaccgtatc gtccacttga tgcagacgaa
    23101 gagagaagaa cgtgaaaaat acgtaagtgg tactgttgaa gatattcgaa tagcgacaga
    23161 agagctgggg atttttgcag aaatctatgg acggccaaaa cacatttatt caatctatcg
    23221 taaaatgaaa gatcagaaaa agcagttcaa cgaaatttat gacttgctag ctattcgagt
    23281 gatcgtagat tcaatcaagg attgttatgc tgtattagga gcaatccaca caaaatggaa
    23341 accaatgccc ggcagattta aggattatat tgccatgcca aaagctaata tgtaccaatc
    23401 tttgcatact accgtgatcg gtccggcagg aaatccggta gaaattcaaa tccgaacaca
    23461 ggaaatgcat gaaatcgctg aattcggggt tgctgcacac tgggcctata aagaaggaaa
    23521 aaatgaaaaa gtagaaccag atggtatgac gaaacaatta agctggttcc atgagatact
    23581 cgaacttcaa gacgaaagct atgatgcttc tgaatttatg gaaggcgtaa aaggagatat
    23641 ctttagtgat aaagtctacg tcttcacacc aaaaggagac gttactgagt taccaaaagg
    23701 atccggacca ttggactttg catacagtat ccatacagat atcggtaaca aaaccactgg
    23761 tgcaaaagta aatggcaaaa tggtgcagct tgattacaaa ttgaaaaacg gagatatcat
    23821 tgagatcatg acttctccaa attcatttgg cccaagtcgc gactggttga aattagttgc
    23881 tactagcaaa gcaagaaata agatcaaacg tttcttcaaa gcccaagatc gagaagaaaa
    23941 tgtgatcaaa ggccacgaat ccgtggtcaa atgtattaca gatctaggat ttacgcctaa
    24001 agatattttg acgaagaaca aactgcaaga agcactcgat cgttttaatt atcaaacaga
    24061 agatgatctc tatgcagctg tagggtatgg agaagttagc cccttgacga tggccaatcg
    24121 tctgactgaa aaagaacgta aagaacaaaa aatcgagcag caaaagcaag aagcagaaga
    24181 aatcatgaat cagccgaaaa aagaacctga caaaatgaaa gtacgtcatg aaggtggcgt
    24241 tgtcattcaa ggggtagaaa acttactaat tcgtatcagt cgctgctgta atccgattcc
    24301 tggtgatgat atcgttggtt atatcactaa aggcagaggg atatccattc atcgtcgaga
    24361 ttgtccgaat gttcagcctg acaaaccaaa tgtagcagaa cgtttgattg aagtcgaatg
    24421 ggaagataca tcgaatacac gaaaagagta tgatgcagat ttggaaattt acggctataa
    24481 tcgttcaggc ttattgaatg atgtacttca aacagtcaat gcgctaacga aaaatctcaa
    24541 cagcgttgaa gcacggacga ataaagataa aatggcgacg atccatttga cggttggtat
    24601 ccagaattta tcccacctaa agagtatcgt ggataaaatc aaagcagtac ctgatgtcta
    24661 cagtgtacgc cggacgaatg gataggagga cagatatgag agcagttgtt caacgggtaa
    24721 gtaaagctgc tgtgtcagtc gatcagcaag aaattggaaa aattggctac ggcctacttg
    24781 ttttattagg cattcatgaa accgatacgc aaaaagatgt ggactatctg gtaaaaaaaa
    24841 ttgcacaaat gcgtattttt gaagatgaac aaggaaaaat gaatattagt gtagaagatg
    24901 tgggaggaca aattttaagt atctctcaat tcacactgtt tgcggatacg aaaaaaggaa
    24961 atcgaccaag ctttgtggaa gccgcacgac cagaaacagc tattccttta tacgaatcat
    25021 tcaatgaagg aatcagaagt cgcggcatca cagtcgctac cggacaattc ggagcagata
    25081 tgtcggtttc tctcgtcaat gatggacctg taacgatcat tattgattct aaaaacaaat
    25141 aaagtaatct ggttttcact agtaaaaact atgaaacacg tcgcttaagt tagactgata
    25201 aactctaact taagtggctt ttttgtctgc aaaaagcgct tcttttgtca gcagtcggaa
    25261 aaaaagttaa gcttaaatta tacaagttat tttttatagg aggttgctga agatgaaaga
    25321 agtaccagta gtagatatca aaatcacaga tttaaaaaaa ttgtatcaaa aaggatacaa
    25381 catgttggag gagttacgcc atgaagcgga cgctcccgtc gtcaaagcaa agattttcaa
    25441 taaagaagct atcacgatct acggatcatc agcagcaaaa gtattttatg atccaaggaa
    25501 tttcaaacga aaaggtgcta tgccaaaatt agtattgaag acactttttg gtcaaggtgg
    25561 agtacagact ttggatggag ctgctcatca ccatcggaaa aatattttta tggatctaat
    25621 gacaccggaa agaatggaag attatcatcg tatcttagat aagaatctga cacaagcact
    25681 tgaagcacag catggtcaat ttgaactatt tgatttaagt aagatggttt tctttacatc
    25741 tatttgcgag tgggcaggta tcaatttatc agcgatttct aaagatgagg tcgaaaaatt
    25801 agcagaatat caaatctcta tgatcagcgg aacgtttact tctccgattg atcacataaa
    25861 aggtgtcgaa aatcgcaaaa aatcagaaaa atgggcgcaa ggcttgattg aagaagctcg
    25921 acaaaatcct gtggctggaa aagaaaatgt ggcattatat gcttttgcca atgccacaga
    25981 tttagatggt cagcttttac ctctggaagt ggcagctgtt gaattattga acatcatccg
    26041 tccaacggtt gctctaactg tgtgggcggc attgatggga catgcacttt tcagtagacc
    26101 agatttgtat cagcaattaa aaaatgactt ttcgacgtta caagatccgt ttattcaaga
    26161 aatgagacgc tattatcctt tcttcccaat gctacctgcg atttcgctga aagaagtaga
    26221 agtagatggt tatcgtatac cagaaggcag ttgggttatt ttagatttat atggaacaga
    26281 ccatgatgaa cgaacagttg aagcgccaga ttcctttatg atcaaacggt atgtagggaa
    26341 agcaaaagat atttcctata aagaagaata tgagatgatt gcacaaggcg ggggaaattt
    26401 tcgacaaatg catcgctgtg caggagaatg gatcactctt catagtctac gtgtgttttc
    26461 cgatcagcta gtaaataagt ttgagttctc tgtacctgaa caagattgga cgattccatt
    26521 caatcagttt ccgacttatc cgaatagccg agcgctactt tacaagaatt agattagcat
    26581 aaacttatcg aaaaaaagga agatcaaaca gtgctgatct tccttttttc atattactat
    26641 aaattgataa ggtcaattga tcaaaatcca cgaaatgctt catcaatggt ttgataatct
    26701 tcattggata aatgcaaatc taaagcttgg acattgtcag atacttgctc tggacgctta
    26761 gctccaggta taactacaga cactcgtgga ttcttcatgt accaagctaa aacaagttgc
    26821 gcaggagtgg cttggtatct tttagcaatg gggcgaagta catcgacagc ggttaaaatt
    26881 tctctgaaac gttctccttg gaaatctgga tttctttttc gaggatctcc ttcaccaaat
    26941 tgtttttcct caccaagttc atattttcct gtcagcaaac cggaagcaag aggaaaatag
    27001 ggaacaaaac tgattttgtt tttttcaaga taagggaata attctttttc agcctgccga
    27061 tggatcaaac tgtatttatc ttctactaca tcgacatatc catctgcatt cgcttctttc
    27121 aattgttcta acgtgaagtt tgacacaccg actgctcgga tttttcctgc ttcttttaat
    27181 tcgtgcaatg tagcaactga ttcatttttt ggtgtgcttt catccggaaa gtggatataa
    27241 aaaatgtcga tgtaatcagt ttgcagacgt tttagtgcat cttccaccga ttgtttgaga
    27301 aactcaggag aattatcaaa tgttcgccct ttatttggta catgagcagc ttttgtagcg
    27361 atgacgacac gtgagcgatc atattctttt tccttcagta cctcgccaat cagttcttcg
    27421 gaacggccgt ttccgtaagc ataagcggta tcgatcaaat tgatcccgct attcaaagct
    27481 gtacgaacta cttgttttcc tgtctcatct tccaaaccgt caaaaagatt atgtcctcca
    27541 acggcatttg ctcctaatcc aagctgttct gcgtagactt gtgaatgtcc gattcttatt
    27601 tctgccatag ctgattcctc ctttttgtct agtctaaaac aaaataccaa aaagctgaac
    27661 taaaacgttt ttgtgagggg aaatagtcag atatctcttg actttgagac tggtttttag
    27721 taggttataa gtaatatcga atgtcaatga aagagcgagt aagtttttga aactttacaa
    27781 gagaggatca tcgaggctga aaatgatcta aagtttcatt agcctaaaga cactctggag
    27841 atggacgagt gaaaagccgt cccgcgtacg agcgttattc gtaagaggaa agagaaatct
    27901 ttcaaaatta ggtggtaccg tgtatgaatt tcattcaccc ttgttcatga tgaacaaggg
    27961 tgattttttt atttacatag ctaagaaagg gagagaaaac tatgagtttc caaagaccaa
    28021 aaggaacaaa tgatattttg ccaggcgaat cagaaaaatg gcagtttgtc gaagaaacag
    28081 cacgtttatt attcagagat tatcagtata atgaaatgcg tacaccgatt tttgaacact
    28141 atgaagtgat atcccgaagt gtaggggata caacggatat cgtttcaaaa gagatgtatg
    28201 atttttatga caaaggggaa cgccatgtga cgcttcgacc agaaggtaca gcaccaatcg
    28261 ttcgttcttt tgttgagcat aaattgttcg gcccagagta tgcgaaaccg ttcaaaactt
    28321 tttatatggg accaatgttt cgctacgaac gccctcaaaa aggacggtta cgtcaattcc
    28381 atcaaatcgg agtagaagca tttggatcag aaaaccctgc aactgatgtg gagagcatgg
    28441 tgatggcact tgatttcttc aaacagttgg ggatcacgca aatccggcta gtcatcaatt
    28501 cattaggtga taaagaaacg cgtcaagcct atcgtcaagc attgatcgac tatcttttac
    28561 cttttgaatc agagctgagt gaagactcta aacgccgcct tcatgaaaat ccattacgcg
    28621 tattggacag taaagacaaa cgagatcaaa aatttgtggc agaagctcca tctatcttag
    28681 attatctaag cgagcctgct caaaaacatt ttgataccgt tgtttccatg ctggatgcat
    28741 tggctgttcc ttatgaaatc gacagtaata tggttcgcgg actagattat tacacacata
    28801 cgatttttga aatcatgagt gacgcaccaa aaatgggggc acaagcaacg atttgcgcag
    28861 gcggacgtta tgacaatcta gtggaagaac taggtggtcc ttcaacacct ggcttcggat
    28921 ttgcaatggg tatcgagcga ttactcttga ctatggaggc agaggaagta gttatccctg
    28981 catttaatga gttggatgct tacgtggtcg cactcggaga cgaaacaaat atcgaagcat
    29041 tgaaagtggt ccaagcgatt cgaaactttg gtttttcagc tgaccgcgac ttcatgaacc
    29101 gtaaagcaaa agcgcaattt aagacagcag ataaagcgaa tgccaaatta gtattggtga
    29161 tcggtgaaga tgagcttgct agtcaaacga ttaatgtcaa agcaatggca agccgaaaag
    29221 aaaaaagttt tccattagaa gagatatatg aacattttga tgaagtctat gatgaaatga
    29281 ctttattcga gtaggaggaa aaaaataaat ggcacaaaga acgatctatt gcggattagt
    29341 ttccgaacaa caattagaac aaacagttac attaaaagga tgggtacaaa aaagacgaga
    29401 ccttggggga gtaatcttta tcgacctacg tgatcgtgaa ggaatcgttc aaatcgtctt
    29461 taatcctgaa atcaacaaag aagcatggga aatcgcggat aaatgtcgca gtgaatacgt
    29521 gatcgaagtg actggggaag ttagaagacg cggagaaaat gcagtaaatc ctaaaatggc
    29581 cactggtgaa ttcgaagtga ttgcaagtga aatcgtgatt ttgaatcaag caaaaacccc
    29641 gccatttcaa attgaagatg atcaagcaat cagtgacgaa atacgtttga aatatcgtta
    29701 tttggatctg cgtcgtccaa aaatgactaa aaacatcaaa ttaagaaatg cgacaacaaa
    29761 agcgattcgt cattatttag atgataatga ctttctcgat atcgaaacac cttacctagg
    29821 gaaatctaca ccagaaggcg caagagacta cctagttcct tcacgtgtcc atgctggaca
    29881 tttctatgcg ttgccgcaat ctcctcaatt gtttaaacaa ttgctgatga atgctggatt
    29941 cgaccgttat tatcaaatcg ttcgttgttt ccgcgatgaa gatttacgtg gagaccgtca
    30001 gcctgaattt acgcaagtag atattgaaac aacgttctta acagcagaag aaatccaaac
    30061 ttacacagag ggattgattg cgaaggtaat gaaagaagtt cgcggtatcg aagtcacatt
    30121 gccatttcct cgtatgacct atgatgaagc aatggctcgc tacggcagcg acaaaccgga
    30181 tacacgtttt gatatggaat tgatcgatct aagcgataca gtcaaagaag tagaattcaa
    30241 agtcttccaa atggctcttg aaaacggcgg tgtcgtgaaa gcattgaatg ctaaaggcgc
    30301 tgcagatcgc tactcacgaa aagacatgga tcagttaggt caatatgtag gacaattcgg
    30361 agctaagggg cttgcatggc tgaaagtaga agaagacgga ttgaaaggtc caattgctaa
    30421 attcatggga gaagcaacag aagcaatcat taaagcaaca gatgcaaaac caggtgactt
    30481 gctgatgttt ggcgcagata aaagtgaaat cgtcgctgct gcattaggtg ctatccggac
    30541 acgtttagga aaagaattag gactaattga tgaatcgaaa ttcaatttct tatgggtaac
    30601 tgattggcca caatttgaat tttcagaaga agaaggtcga tatgtctctg ctcaccatcc
    30661 attcacgatg ccaaaagaag aagatatccc gttattggct gaagaccctg caaaagtcta
    30721 tgcagaagct tatgatatcg tcttgaacgg ttatgaacta ggcggaggtt ctatccgtat
    30781 tcatactcgt gagcttcaag aaaaagtact agaaactcta ggctttacaa aagaacaaat
    30841 ggaagaacaa tttggtttct tgttaacagc tttagattac ggattccctc cacatggcgg
    30901 tattgcatta ggattggacc gttttgcaat gttattagcc ggagaagata atattcgtga
    30961 agtcattgcc tttcctaaaa acggaaaagc agcagatgtg atgagtgatg caccaagtat
    31021 ggtttcgcct ttacaattgt tcgaattgaa tattgatgta acgaatatag aagaatagcc
    31081 gataaaaagg taaaaaggat ttgtcgaata cgcttctttt gacaaccttg atttaattga
    31141 aaaacacttt ataatgaagc cataacatat aaagcggggc ttttccatga aaaaaacatt
    31201 cgaaaattgg gcttatcatg attacacgac caagctttcg gtatctatcg tttatgcgtt
    31261 gatcgcatca gtcgcattga atttctttta tcagccagga catatttatt caagtggtat
    31321 tactggtcta gctcagattt tgacgacttt gtcaaaatca ctgataggat tcgaagtacc
    31381 ggtatcaaca actttgtatt tactgaatat acctttgttt gtattggcgt ggttaaaaat
    31441 cgggaagaag tttacaattt tcacttttat cacagtcact ttgacctccc tttgtatcca
    31501 tattttaccg gaaacagtcc tatctaccga tccaatcatc tgtgcgttgt ttgggggggc
    31561 tgtgatggga ctaggtattg ggctagcgtt gagaaacggc ctatcatcgg gcggtctaga
    31621 tatcgtgagt atcacgattc gtaaaaaaac aggaaagtcg attggttcta tttcgatcta
    31681 cttcaatgca ttgatcgttt ttgttgccgg aattctattt ggctggcaat atatgtttta
    31741 cagtacgttg tctattttcg tcagtggaaa agtaactgat gtcgtttata ctaaacaaaa
    31801 gaagatgcag gtaatgatcg taacgaaaca tccagaaaaa gtagtaaatg aaatccaaaa
    31861 ctgtatgcgt agagggatca cgatcatcaa tgaagcagaa ggtgcttata agcatgataa
    31921 gcagacagta ttgatgacga tcgttacacg atacgaactg cctctactta gagaagcaat
    31981 gaaagcttct gatccacaag cttttgtaag tattgcagaa aacgtccaga tacttggtcg
    32041 tttctatgag gatggcattt agatcgagtt tgacaaaaat tcatgaaata ctgctgtaga
    32101 cagacgttcg tttgtctgca gtttttttct accatagtag aatcagcaaa gaaaaactgc
    32161 ttttttattt gaaattttct taaagttgaa aaaaagcatg tttatttttt taaatttatg
    32221 ggatgataga aaaaaatagt agagaaagga cacgattcta cttgctattt tcacttaata
    32281 cccgtatatt acgaatgaaa aaagtttatg aaaagttgga atattgaatg gaaaaacaaa
    32341 aaaggttaaa aaacagccgc tacatcactg ggtttgatgg gctccgttca ttagctgtgg
    32401 tgggtgttat cttctatcac cttctgccaa ctagtatgaa aggcggctat ttgggcgttc
    32461 cgattttttt cgtcgtatct ggttatttga tcacggatct gctgcggcag gaatgggaac
    32521 aaaatggaaa aatcaatatt tggcaatttt atgtcagaag aatgaagaga ctctatccgg
    32581 cacttgtttt tatgcttgtg acagcttcgg cttatatcac tttgtttcag cgagggctgt
    32641 taaacaatct tcgaggagtt gtggtcagca gcttactgta tgtcaacaac tggtggcaaa
    32701 tcaataacgg tttatcttat ttcgatcgat ttgctaatga gtcaccgttt acgcatatct
    32761 ggtctttagc agtagaaggt caaaactatt tggtttggcc gatcttgttt gtattgttga
    32821 tggtatttgt tcgtaaaaga aaatggatct tttatactgt gttaggtaca tccttcctct
    32881 ccgccatctt gatgatgatc ttgtatacac caggaggcga tccaacccgt gtttattacg
    32941 gtaccgacac tcgtctgttt tctatatggt tgggaagtgc gcttgcgttt gtttggccaa
    33001 gtacgcgttt aaagaaaaac atcccgaaac aagcgaaaaa tattctgaat atcgctggag
    33061 gaatctcgct tttggcactg attctttgct tcttcttttt agatgatcat tacaatttca
    33121 tctattacgg aggaatgctc ctagtgagtc tgttatgcgt agtgctagtt gcagtgacag
    33181 cacaccccgg agcaagtttg aatcgatggc tgacaaatcc agtatttact tggattggca
    33241 aacgaagcta tggcatttat ctgtatcagt ttccagttat gattttttat gaagcaaagg
    33301 tgactgatat tgccgatcat gttttgttgc atactttagt ggaaatcaca ttgattctaa
    33361 tcatcagtga actttcttat cgatatgtgg agcgtccgct agcacgtttt gattatggtc
    33421 gtacattcca agtgatgaaa ggatggttca gcaaaccgat catcagtaag agcaaaccat
    33481 gggttgttcc aggcacatta cttgtagcaa ttgcactcgt tggtttcgtt acggcaccga
    33541 aaaacgctgt aacagccgat caaaaacaac tgcaggcaaa aatcgctgaa agtaaaaaat
    33601 tagcagaaga aaccagaaac aattcagaaa acaccactag ttcggttgac caagcgatcc
    33661 ttgataagta cgagttgtcc aaggcacaag ggaataaggc acaaaaatta gaactaacgg
    33721 catttggtga ttcagttatg ttggatgctg caacggatct acaagaactt tatccaaaag
    33781 tagtggtaga tggagatgtc ggacgacaat tatatgccag tgtaccgtac attgaaaaat
    33841 taaaggaaca agatttgttg aaagacactg ttctgatcgg actaggaacg aatggctcat
    33901 tctcggaagc tcagtttgat agtgtgatgg atgcaatcgg tgatcgaaaa gtatactggg
    33961 tcaatgtccg agtaccgacg aagcgctggc aaaatgacgt gaatgcgatg cttgaacaga
    34021 tgacgaaaaa atacgacaat atgacgctga ttgattggta cagctacagt aatgaccata
    34081 gtgactggtt ttatgatgat caagtccatc caaatcctga agggatgaca cattacattc
    34141 acttagtcag cgaagccttg ctaggaggaa gttcaagtac gaacagcagt gagacaaacg
    34201 tgacagaatg atagctacaa aaaacttcag gcaaaaacat ttgtttttgc ctgaagtttt
    34261 tttatattta ccgtgttttt aacattcata tagattcagg aagcaaaacg gttgagtgtg
    34321 tctgtaaata acgttctttt tgttttcggg tgagtttttt gaatgcagct tctgcttttg
    34381 ttgcttcgct tcttgaagaa aatacttctg catggatcat cttaacaggt cttctttttt
    34441 gaagacgagt atatttagca ccagtaccat tgttatgttc ctctaatcgt ctagaaagat
    34501 cggttgtata tccaccataa aatgtctgat ctttacagaa taatacgtaa aaataatgtt
    34561 catttgccat agagcatctc acgaatctct gcagtgtatt ctccatccat attgtaagtg
    34621 atcaatggtg gagcgacttt gaatccgtct aatttgcctt ctttgattcc ttcaactaac
    34681 aaaatatttg cctcttttcc aggttttggg taaacaaatt ggatcctttt aggtgcaatt
    34741 cgatagtctt ccatgacctg aatgatttct aagaaccgat caggacgatg gaccatagta
    34801 aagcgtccat ttgtttttag tagcttactt gaaatatcga tcacttcttc taacgtcgta
    34861 tgaatctcat gacgggcgat tgccaggtgt ttattagggt tcgttttatt tgttggcagc
    34921 cctttgaaat aaggtggatt acagacgact aagtcacaag aattatgtcg aacgacagat
    34981 aagctgtctt tcagatcgat ggtgtggaca gtcatttgtt catttaaatg gttaagcgcg
    35041 atactacgtc ttgccatgtc tgctagacga ggttgaagtt cgatagcgtc gatagccgcc
    35101 tgggttcgtt tacttaaaaa aagtccaact gcgccatttc ctgcacaaag gtcaacaatc
    35161 ttcccttttt taggtacacg ggaaaagtga gcaagcagca cagcatctaa agaaaaagaa
    35221 aacactttgg aactttggat aatcttgata tcttctgcgt ataattggtc gattcgttcg
    35281 tcttcgtgaa gcatggattc cctccaaaat gaaaaaaata gtcgtctgta ttatactatt
    35341 tttattaaaa agaaccaagg tggcttgtca aacctctatt ttttatgcat actatgacca
    35401 taagaaggga aaggaagaga ctatgtttta tcgatttatg cgcggggtag ttcgagtact
    35461 attagcctta gttaatggaa atgcccgcta tgagaataaa gaagttttac cgcaagatga
    35521 gaattacata ctagttgctc cccatcgtac ttggtgggac ccattatatc tggcggtagc
    35581 tgcagcaccc aaggaattca gctttatggc aaaagaagaa ctgttcaaaa atccagttct
    35641 gcgatttata ttaactcgat ccaatgcttt tccagttaaa agagaaaatc caggaccaag
    35701 cgtcattaaa acacctgtaa agattttgaa atcgacaaat ttgagtttga tcatgtttcc
    35761 cagtgggaca agacatgcta cagaacttaa aggcggaatg gcattgattt ccagaatgtc
    35821 taaagcgaaa atcgtgccag ctgtatatca aggtccgttg acacttgggg atctgttcaa
    35881 gcgtcagaga gtgacagtgc gtttcggcga accaatcgac ttatcagata tcaagaaaac
    35941 ggataaagaa ggtatggcgg agatcgaacg acgaacacaa gcagcttttg acaaattgga
    36001 caaagaagtg aaccctgatt tcaaatatga agtcaaaaaa aaataaaatg ataagtttat
    36061 gcgtgggcgg tcttttgaat ctactgtcct gttcagttca gactttttca atgaaaacga
    36121 gggagagacg tcaagtctgc cctctttttg cgttccaata tgtaaaatag aagacaggtg
    36181 tcatgtaatg gatcaaagtg ttataataat tagaaggaca ttttttgagg tgattgaatg
    36241 cgttttttac atacagccga ttggcatatc ggaaaaaaac tacaaggtta tgacttgatt
    36301 gaagaccagc gtcatgtact atcttctata ctagatatcg cgaaagaaga aaaagtagag
    36361 gcaatcgtga ttgccggaga cttatatgat aggagtgtcc cagctgttga tgccgtagaa
    36421 ttatacaatg aattgatggt cgattggaat ttaaaggaaa agatcccgat ttttgctata
    36481 tcaggaaatc acgatagcag tacgagactt tcagcgggta cgccatggtt cagttattcg
    36541 aactattttt tgcgaacaca gctagcagaa gcatttgaac cagtcgagtt taaaaacgta
    36601 caatttttct ttcttcctta ctttgaacca attgcagcga gattatattt tgaagatgac
    36661 aatatccgaa cgatcaagca agcggtagcc aaggtgatag ataaaatgca ggagctattt
    36721 gattcagaaa aaaaacaagt attgattagc catttttttg taatgggaag tgtaaaatct
    36781 gattcggaaa cgaaaatcga agtaggcggg ttggattcga tccctggtga actacttaca
    36841 ccgtttgatt atgtagcact aggacatttg cataatcaag ctgctttgag acaggataat
    36901 gctcgctata gcggttcccc attgaaattc tctttatctg agatcaacca aaaaaaaggc
    36961 gtatggatcg ttgacctgac aacaggcctg gagttgaatt ttagggagat cgaacccctg
    37021 catgatattg aagaaataac agcgagtttc aaagaattgc tggatcctgc cttttatcag
    37081 tccgtcaatc gggagaatta catctatatc tatctcactg atagaacgat catcccgaat
    37141 atgatgaacc agcttcggca aatatatcct cgtattttgg ggattgaacg ggcaaacggt
    37201 cgagcagaac aaacaaagcg caaacgaaaa gtactagaaa tgaaagatcc tcaaaaatta
    37261 gcagaagcat tttttagtga aatgacggaa gagcagctaa ctgcaaacca agaaaaatgg
    37321 ctcggagaaa cgttgcaaga aatcatggaa atggaatgat caagaatgaa accgaaaaaa
    37381 ttacaactta aaaattttgg tccttttatc aatgagaccg tagatttttc acgtttgaca
    37441 gaagcaccgc tttttttgat cagcgggaag acaggagctg gcaaaacgac gatttttgat
    37501 gggatcacct tcgcactttt tggtgaaact tccggaagac ttcgctctgg aaaagagatg
    37561 cgttctttgt ttgctacacc agacgaagaa acaagcgtga ctttttcttt tgaacatcag
    37621 cagatgagct atgaaatcga acgaaaacca gaacaagttt tagcaaaacg aaaaggaaac
    37681 ggaacaaaaa aacaggcagc caaagtaacg ttgaccattt ttgatgggaa aggaaaagaa
    37741 ataaaacaaa tcacaaaacg tacagaagca gatcagttga tcagagaact gatgaatctc
    37801 gatgcgaaac agttttctca aatcgtttta ctaccccaag gagaattccg taattttttg
    37861 gtttcatcaa gcagtgataa agagactgtt ttacgtcatt tattcggtac tcaatttttc
    37921 caacagttca atgagcgatt aaaagaaaaa gcaaaacaac agcaacaaaa attggatcat
    37981 ttagagcaag agctgcatct tctgcaaaaa aggtttgttt tagtcaaaga agaggaacca
    38041 gcagcagggt ttgaagccgt tttagcccaa tggacaaacc atcaggcaat actcgaaaaa
    38101 caaatcacgg aagaaaaaga agctctaacg gaacttcagg aaaaacaaaa gcaactagaa
    38161 aattcctact atcgttttga aagcttgaaa aaaagttatg aagaaaaaac gatattaata
    38221 aacaagcaaa aggaattagc tgctcaaaaa gacgaaatag aggaaaagaa acgatggatt
    38281 gggtattatg aatttacgca acgattagtc gaaccaatcc agcgcctaca agaaataaaa
    38341 gttgaaaaaa tagaactgtc acaaaaaagt agtgagcaaa caaagaaact agcgatgact
    38401 acgcagaatt atgaagagtg gcaaaaaaat gaagcaaacc gcgtacgccg acaaacaaaa
    38461 atcaaagaag ctgctcaaaa actgcaaaac aaacagatga tggtgccaat tgtcgaatcc
    38521 ttacgtagta aaaaacaaga cgcagaacaa ttaacaattt cattggataa agaagaattg
    38581 aatgccgaga agctgtatca aaatctcgct atctatcagg aaagaactcg aattcttcaa
    38641 gaaaatttac tggatcagga aaaactgcaa gaagatcgtc ttgcttttgg acagttaaaa
    38701 tatctagatg aaaagcagca agaaatagaa aaacaaaaag caaaagacac tgggtcgctc
    38761 gcacagataa gagaagaact caaaaaagca actgaagaaa taacaaaaaa tagtcagcta
    38821 ttgaaagaac agacagaaca agcagaacag ctgaaaagcc aatgggcaaa gcagcaaatt
    38881 gctcgtcttc agcttttttt gcgtccaggg gagccatgtc ttgtttgtgg atcaacggaa
    38941 caccccatac aacaattaaa acacgaacag ccaaataagg aagatatctt aaaagtagaa
    39001 caacaactgg cagaagctga gtctgctgta gaaagaactc agcaaatcat tgccaaaagt
    39061 gaagcacatg aaaataatct tcaacaacaa ttatcagatt tagaacaaaa aatcatggca
    39121 acgaatatac aattggctga acaagaagaa cacttgcaac aggctttgaa aaaggcattt
    39181 cctgagataa cagaacaaaa aacaaaaaca actcttgtag taatcgaaca atctttagat
    39241 agacgaaaaa gcaagatggc caatgcaaga atagagctgg aagaaataag acaacaagca
    39301 gaaaagctcg aacaacaatt agctgtctac aaacagcagc agacagaaaa aaataatcag
    39361 ctccagcaac tgcaaggaga aatcaaaagt ttagaacaac aattgcaaga tacggatagt
    39421 aactgtttag aagaggagat acgacgactt gaaaaacagt tagaagaaga ctcgaatcaa
    39481 ctagctgttg agcagaaagc aggagtgcaa ttgttgcaag atcttcatac gcttcggaca
    39541 cagcttgatc ttcaacatga acaaatagaa aaaatagatg aaaaaataga aaaggaacaa
    39601 gaaagaatag ctaaaaagtt agaaagccag tcgtattttt caacaattga agaaatctgt
    39661 gcatttgcac aacagcaagc acaatataaa gaaaaccaac gtacagttac ttcttatcat
    39721 gaagagcaat tagtgacagc tgaccggctg cgtcaattag aaaatatcca gctaactgag
    39781 acattcccag atacagaaga gatcagccaa cagttagaag aaataagacg tatgatcgaa
    39841 ataaagcaag aaaagatata cggtttacaa gaacaaaaaa ttagtaatca aaaaatctac
    39901 gatgaatgtc tttcgattta tcacacaagc cagacgaaat tagatgagct tacgcaatta
    39961 cagcagcttt cgcaaacatt caacggagaa aatcctaaga agactagttt ggaacggtat
    40021 gtgcttcagg tttatcttca agaagtgtta caagtagcaa atgatcatct ccaacgttta
    40081 acgaaaaatc gttatcaatt tgagctagcg gataccattg gcagttatcg agggaaaacc
    40141 ggattagaaa tcaatatcta tgatgatcag gcaggtatgt ctcgaagtgc gcataccctg
    40201 tctggcggtg agagttttat tgcagcactt tctttagcat tagctcttgc cgatgtgatc
    40261 cagacacaag ctggtggtgt agcaatcgat gcattgttta ttgatgaagg atttgggtca
    40321 ttagatgaag aagctttgga aatggcaatg gaagctttag aaacgatcga aagtgaagga
    40381 agaatgatcg gcatcattag tcatgtaaga gaattgaaag aacgagtatt acaacaaata
    40441 agaattgata cagaaggtag cggacaaagc aaaatacgct atcaacttgg ataaaaaggg
    40501 agattggtaa ctatgaaatg gagtattcca gaaaaagtca ttgcacgtgg acgtcaatac
    40561 ttgcaagaag gccgagtgtt atcggttgtc cctgaccaag aagaaaacgt gtggcatgca
    40621 gaagtcttgg gcagtgaatt gtatatggtt gatttggatg gtacagcaaa agagatagat
    40681 tactgccaat gtccctattg ggaggaacat aaatattgta agcatacagt tgctgtggaa
    40741 ctttatttac ggtcgaaaaa tctatctcgt atcatgaaaa aagaccagcc aatgctagaa
    40801 ccggtaaaag caacaagtga gggagaaatc attgcaaaag gtttttctcg tctaaaaaca
    40861 caaaacaatc ctcaagcggt gcaacctttg attattgaat accaagtaga aacgattgag
    40921 actaatcagt atcacccaga gctttctatt ttggcacttt acttgcgtat cggttcattg
    40981 gcatcaccga aaaaaacata tatcgtaaaa aacatctatg attttttaca agcttacaca
    41041 gaaaaagaaa cttacactgt taataaacag taccagtttc gtctagataa acgggcgttt
    41101 caaaaagaag atcaaaaaat actcacgcat cttgcaggaa gtgctcagac gcatcaatta
    41161 ttaggtacga acggcttaca agtcaaagga aaactagata aaagatatct gcttctccca
    41221 gtagaacaag cccgcttcct gttagagcag atgaatcaga ctacacgttt gcatctgcag
    41281 ataaatgaac aaaacgatca aggaatacaa ttttccgatc aaaacaaacc tttatcattc
    41341 aaagtggaaa aatttggaga agattatttg ctgcaagcat tgaatgattt tgattttttc
    41401 tttatgcatt atcagtgggg agttatccaa gggacatttt attctctgac gaaatatcaa
    41461 caaacggttt atcaaacttg gaaacaattg attcgccgat tggagaaacc agaagtagtg
    41521 ttcaagaaaa aagaattacc gtctttgttt aaagagatta tccctctgct gtcagagatc
    41581 ggcgacgtag ctattgcccc tgcagtagaa gaggaagtag cagatatccc cgtcgaattt
    41641 attttctttt tccgaaaagc aaaaggaaaa atccaagctc gagtcgattt cgtctatggc
    41701 gaagtcatct attcgactga cccgaagcat gaggtctcga cagaacaggc ttttcaggtg
    41761 ttacgtgaca cagtagaaga gaaacgagta cttgatctat tcagaatgta tcgctaccag
    41821 aaaaatgaaa ctggttatga acgtccattg ccaagcgggg aagaactata tgcctttttc
    41881 cgcacagaac tatctgtctt ccgtcagttt ggtgaagtca gacttggaag aaaattgcga
    41941 gagttgtatt tagatgcgca taaacatcaa ccgaaaatcg aagtaaccga gaccggttca
    42001 tggctcgata ttcgattcga tgtgacaggg atagaggagc aagaaatcga tcatgtcctg
    42061 caaagcttgc tgagaaatga tgctttttat acattagaaa atggtcaggt tctttctttt
    42121 gattcagaag aatttcaaca aacaagccaa gtgttgcaac aattacggga atcgatacgt
    42181 acagaagaag gaacgatcca tgtacctaaa aatcaaggat tgatcattca aaatcaattg
    42241 gaaaaaagca atgctacttt tagtgaatcg ttccaaacga tggtacaaga tctcattcat
    42301 ccagaaagat accaggcaca gcttcccaaa ggattgaatg caacgatgag agattatcaa
    42361 aagcaaggtt ttcgatggtt gaagatgtta ggtcattatc agtttggcgg tattttagcc
    42421 gatgaaatgg gacttgggaa aacactacag acaattgcct ttttactttc ggaaaaagaa
    42481 gaacggaaaa gcttctctgc tttgatcgta gcgcctgcga gcttaattta caactggcag
    42541 gcagaggtga gaaaattcgc cccttcttta agtatccaag taatcaatgg gaataaaaaa
    42601 gaacgtgaag aattactggc taaagacaca gatatccgag tgacttctta tgccagctta
    42661 agacaggatc tagctaatta tcagtcgcaa aaaattgatt atttgattct tgatgaggca
    42721 caaatggtca aaaatagcag tacgaaaact gcacaagcat tgagagaatt agctgtacct
    42781 cagcggtttg cactgagtgg gacaccaatc gagaataatt tagaagaatt gtggtcattg
    42841 tttgcaacga ttatgccagg atttttcccg actaaaacaa aattcaggga acttgccgca
    42901 gaagaaattg cgcaaatgat tcgaccgttt attttacggc gagataaaca aactgtgttg
    42961 aaagacttgc cggaaaaaac agagatgaat ctatattctg cacttacaga agaacaaaaa
    43021 actgtttatt tagcttactt gcgtcaaatg cgtgaagaaa tcacatcaat ggattctgaa
    43081 gcattcaaga aaaaccggat cgggatactt gctggtctga caagactgcg acaaatttgc
    43141 tgcgatcctc gtctgtttat tgaagattac caaggcggtt ccggcaagct cgaacaagta
    43201 aaagatctac tggtagctgc caaagagaac aaacgaagag ttttgctgtt ttctcaattt
    43261 acagggatgc tgactatctt gcaagaagag ttagccgagc tagggatctc gacattttat
    43321 ttaagaggca gtacgaaacc acaagatcgg ttaagtatgg tagacgcatt taatgctggc
    43381 gaaaaagatg tttttctgat ttccttaaag gctgggggaa ctggattgaa tctcacggga
    43441 gcagatacgg tcatcttgta tgacctttgg tggaatcctg ccattgaaga acaagctgct
    43501 ggacgtgcac atcggatcgg acaaaaaaat gtggtagaag tgtggcgtat gatctctgaa
    43561 ggaacgattg aggaacgcat ggattcactc cagcaagaaa aacgcgaact gttccaaaaa
    43621 gtgatccaag gtaatgaaga acagttgacg aaactgactg aagaagacat ccgcatgatt
    43681 ttaagtgtag gagaaatcga ggagtaagag actcgaaaaa gcgttcagta atgggtaaga
    43741 aagcctttct aaagaagcga ttgtttattt gatttaaaaa atagcaagga ggctgggatt
    43801 ccattttatc ccagcttcct tgctatcatt tttttatttc tatttttaaa ggttatacaa
    43861 agattgtctt cattgtctct aacagctgat caaaagaaga aatctcgata tcgcaaattg
    43921 gagtctgttc aattttgcgt tctcgatggt tgaaccaaag cgcttgccag ttagcacttt
    43981 ttgcacctag aacatcattg tcgtaattat cgccaacgta taaggtctct tctggaagca
    44041 tatgaaattc tttctcagct agctgaaaaa tctctttttc tggtttttgg aaacctgttg
    44101 cttgagaaat gagcatattg cgggaaggaa tccaattgtt caattgaagt tgcttcagtt
    44161 tttttgtctg atggtcagtc ggcccatttg tgataattcc taatgggaca ttcttttcct
    44221 tcaagaaatc gagggttttt ttgacctcct catgcaagca gatattatca agttcttcct
    44281 cgtaaatttt ttgaaataag aggccatctt cttccgtaat atgagggtag tctaaatctt
    44341 ttagtgattg gctgatccga tgtgctcgca tatattctag tgtccaatct cctgccatta
    44401 cttttgggaa gttttcatca ctatgatggc ggaaccggat atatagtgga tgcatatctg
    44461 catctgaaac aagcggaacg actcttttga ccgcgtttcg aaatggctgc tgctgatcat
    44521 acatcgtatc atcaacatca aacacaactg atttaatcaa aattttacac gcctttcggt
    44581 tttcattgat tttttcacaa atccttgact attgtaacag aaaaaattgt ctaaaaaagc
    44641 tgataaataa aggtttttct tactatattt ctatttcctt gacagaataa ggtttttata
    44701 tttcagtttt tttcactaaa aatcgtgaaa cacgtcaata agtttgatga acaaattaat
    44761 cattatggta gaagtcgatt gatttatttt aatgcaatct ctgtggaatt ttcgaaagat
    44821 ttattttttt aatacagtct caatataact attcaaacat aaaataacgt tatttgattt
    44881 atttgtttat agtaaatttt atttagtaat cattgcttta aaatactacg ctta
//
LOCUS       DAZKKZ010000018        44912 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.018, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000018 DAZKKZ010000000
VERSION     DAZKKZ010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 44912)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44912)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44912
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.018"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..1827
                     /locus_tag="ACG8LA_001059"
     CDS             <1..1827
                     /locus_tag="ACG8LA_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0203373.1"
                     /translation="IYNKKESFYLRIKWSIIIILSLLFLTGIAYFFYFIFSPADSNQM
                     KEIKDSWVFYTKDDPDFKFDSKYTRTIPTVDKDETFIMETTLEKPLDEANLLIKGNHQ
                     WITVYLGEKILYQRKDYQEESNPGLSLAVIDLPANYIGKKLTLTVSSPYQNYAGLPPK
                     VYLGTTGPLISFIYSQSVPQVLTMIIAVFIAIGTFFYTIYLMYKQKRLEYSLILLSCF
                     ALALGFEAVSEDILSGILFEPFVHSFLSHLFIILTSAFIICYYWSRMFYYKKWYGIFC
                     TFQLLIFIGVLLYATFTPAELPELMPIANIASVISTLVTSLACIGEAYKNNRFYVACT
                     PWIVLVAIIHCLIYIQTALGIYQTTINWSTILYIIILIVIISYNLIDHILNTDKDRRQ
                     VDFLKIKNDLLEQHYEQLRQHIQEVNTLRLEFVQEMENLQDLMHTDQTKAKNYVEKIL
                     EEAKNFEMLCSFCNHQVTNLILARYQKLAAKRNIQITFQADLPEELPINDDDLAQLLI
                     HALEHSFRETHAIENPLYRKIYLSIHEQEEHFVICCEHSAHYDTNLFSRGITEELDDQ
                     ERFDLMMMKDVADRYTGTLTQEKDTFIDRITVQLSRNYPNPV"
     gene            complement(1872..2876)
                     /locus_tag="ACG8LA_001060"
     CDS             complement(1872..2876)
                     /locus_tag="ACG8LA_001060"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0017118 - lipoyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009249 - protein lipoylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HFQ0203374.1"
                     /translation="MIFVPNENHDPRINLAIEQYLLQEMPLDEPILLFYINEPSIIIG
                     RNQNTLEEINRDYVEENGIHVVRRLSGGGAVYHDFGNLNFSFIMPDDGDSFRDFAKVT
                     QPIIQALHELGVAGAELKGRNDLVIDGMKFSGNAMYATNGRMFAHGTIMFDSDINEVV
                     NALKVKKDKIESKGIKSIRSRVTNIKPFLPEEKQKMTTEEFRQEILLKIFGVESVEEV
                     KTYELTDEDWKKINRISEEYYRNWDWNYGKSPDFNFSRQKRFSIGSIEVHLNVSEGMI
                     KEAKIFGDFFGLGDISDVEKKLVGQKYDKASLSKIVSQIDVKKYFGAIEPEELLTLLY
                     "
     gene            complement(2887..3627)
                     /locus_tag="ACG8LA_001061"
     CDS             complement(2887..3627)
                     /locus_tag="ACG8LA_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HFQ0203375.1"
                     /translation="MKLTVLGCLGAYPYKNQGTTGYLLQSDGFNLLIDAGSATLIKLQ
                     EHLDPLDLDAVILSHYHHDHIADLGVLQYYWQLHPKRNPETLLSIYGHTKDSIHFEEL
                     TLENVSKGHPYFEAEELKIGPFLITFMETIHPVVCYAMRIVEETTGKVFVFTGDSGYL
                     ESFADFAKDADLFLADTYLFEGNEHHHAHFTSKEAGELAKSANVKKLVLTHLPQFGDL
                     EQLKNEAQKAAGKGIDIELAAVDKVFNI"
     gene            complement(3697..4500)
                     /locus_tag="ACG8LA_001062"
     CDS             complement(3697..4500)
                     /locus_tag="ACG8LA_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HFQ0203376.1"
                     /translation="MNNRIPISEYRKKARVSLENQWGINTWLVFLSIIFTSVIQNFFD
                     GFSPFPEESMQQHLLSFLVDNLLLFAFNYALFYIALVVVRGGRPKSNLLFSVFQRKYF
                     GSILGINLINSVINWLLNSLIFLPMFLISGVSTYMQLLFSSNAVPTGVMPEDFLDISF
                     VLSMIGMIFVSALIMSIVGGLFQFAAWTKFDYPDLSVIQCLKYGWFLLKDRIGTYILL
                     QLSFIGWYLLGAIALFIGLLWVIVYVNVSVAEFYEQARIEKGGPDAYFT"
     gene            complement(4500..5582)
                     /locus_tag="ACG8LA_001063"
     CDS             complement(4500..5582)
                     /locus_tag="ACG8LA_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HFQ0203377.1"
                     /translation="MDTKEEQLLIDLTSAKGVPGNEEEVREVFREYAKPFADDIFYDG
                     LGSVIAKHGAGGGPKVFISGHMDEVGFMVTKITEKGFLEFQTLGGWWGQVMLAQQVEI
                     KTREGKIVHGVIGSKPPHVLTPQVRNKPYEIKDMFIDIGASSQEEAKEWGIRPGDMVT
                     PYIEYKRMNGSKYLLAKAWDNRIGTAVSLRVLENLSKEAHPNVLFAGSDVQEEVGLRG
                     ARTSTHLVNPDIAFALDTGTAGDTPGMTPKEADSILGKGPQILIFDASMIPHKKLLNF
                     VIDVAEEMDIPFQYTVISGGGTDAGQMHLTRDGVPSVAITVPVRYLHSHTSVIHEDDY
                     LNTVKLVTELVKRLDSETVEKIRSYE"
     gene            complement(5723..6991)
                     /gene="dltD"
                     /locus_tag="ACG8LA_001064"
     CDS             complement(5723..6991)
                     /gene="dltD"
                     /locus_tag="ACG8LA_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0070394 - lipoteichoic acid metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HFQ0203378.1"
                     /translation="MKKKLFAIFGPVVLAVGLLFVFFTSSYQVDISNPETIRRASSSM
                     SVNVLKGDAIKNYALSEKQYIPFFGSSELSRISPFHPSVLAEKYQRNYRPFLLGAPGT
                     QSLSQYMMMRSAGDAMKNKKVVFIISPQWFVKNGVKTDYFNTYYSELQTYDWLFSMKK
                     VTPADRYLARRLLTFSKVKENDTLTAILQTIKKGKLPLPESLNQLRSQWNMLKREDEV
                     FSNIGLKDRQQKIDHESKRLPKQYQETELSILANQIGERETTNNPFGLKNDFYTHRIR
                     AHEPELKQSQKNWDYRFSPEFSDFQLVLDQLAKNHNEVLFIIPPVNEKWSDYTGLSQE
                     MLQGFAKKIKFQLNSQGFNRIADFVNQAGTNYFMEDTIHLGWKGWLAADQQIRPFLEE
                     NHITASKYHLDDAFFSKSWQHQIPDKLQLK"
     gene            complement(6994..7227)
                     /gene="dltC"
                     /locus_tag="ACG8LA_001065"
     CDS             complement(6994..7227)
                     /gene="dltC"
                     /locus_tag="ACG8LA_001065"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0036370 - D-alanyl carrier activity
                     [Evidence IEA];
                     GO_process: GO:0019350 - teichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HFQ0203379.1"
                     /translation="MEEQILSILEEITGTDEVRKNRDIDLFDEGLLDSLASVQLLVEL
                     DGELDIQVPVSEFEREDWCTPNKIIQQATALKG"
     gene            complement(7272..8477)
                     /gene="dltB"
                     /locus_tag="ACG8LA_001066"
     CDS             complement(7272..8477)
                     /gene="dltB"
                     /locus_tag="ACG8LA_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0070395 - lipoteichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HFQ0203380.1"
                     /translation="MMLPHMIPYAEPFYFFLLAIALVPIVLSLLIWEKRLPVYQSAVT
                     LFFLFVSFGGNYWQQGAALIGYVLWQTILVWGYFVYRQRKNQTGWFFAAVILAIIPLF
                     LTKVTPFFEHGKASLLGFLGISYLTFKSVQMIMEIRDGMIKTYKPFRYIQFLLFFPTI
                     SSGPIDRYRRFEKDQLHPPVRDKYVDLLGKGVQNIFVGFLYKFIIGYYFGQVLLPVVG
                     RIALQHGGISWALVGYMYVYSMYLFFDFAGYSLFAVGTSYMMGYQTPINFNKPFLSWN
                     IKEFWNRWHMTLSFWFRDYVYMRLMFFMMKKKFFKSKIVMSNIGYFALFLLMGIWHGL
                     TWYYIVYGLYHACLICLTDAWIRFKKKHKEQLPSNKFTHGLAVFLTFQAVCFSFLIFS
                     GFLDKLFFS"
     gene            complement(8474..9988)
                     /gene="dltA"
                     /locus_tag="ACG8LA_001067"
     CDS             complement(8474..9988)
                     /gene="dltA"
                     /locus_tag="ACG8LA_001067"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0047473 - D-alanine [D-alanyl carrier
                     protein] ligase activity [Evidence IEA];
                     GO_process: GO:0019350 - teichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HFQ0203381.1"
                     /translation="MEIKTIIEAIDDWGINEPDRVAYQADETHTFGELKQASDALAYY
                     LEKKVEGDGPIVVFGNLEFEMIVSFLGVVKSGHAYLPIEEHTPKERILSIFRVAKPSM
                     VISIGDWIEDIPSVPVITKKEFQEIKKIPVGFYPRNSVKGTENFYIIFTSGTTGEPKG
                     VQISHDNLVSFVQWTMEDFGIKPGMHFLAQAPFSFDLSVFSIYPALVSGGMLKPLNKA
                     VVQDFRQLFATLPALKLNVWVSTPSFMDICLMEPTFNGENVPELDMFLFCGEELTKKT
                     AESLLDRFPNARIYNTYGPTEATVAISSIQIDQHVLDSYDRLPIGYVKKDTKVSIVQE
                     GKPVSKGETGEIIIAGPSVSKGYLNNPEKTAAAFFCQNDLASYHTGDAGRLDEYGLLF
                     YEGRMDQQVKLHGYRIELGDIEHYLLQDNRIKQAVVVPKYQGTKVQQLVAFVVLENKT
                     KQPDFQLTKSIKEQLLEVVMDYMIPQKFHYVDLLPQTVNGKIDRKKLTAEVNPE"
     gene            complement(9999..10148)
                     /locus_tag="ACG8LA_001068"
     CDS             complement(9999..10148)
                     /locus_tag="ACG8LA_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HFQ0203382.1"
                     /translation="MNKWRSNPKLNYWGKFIIRTIFYSAVLLFLIYLYHYKNIQGGTF
                     IYNEF"
     gene            complement(10429..12471)
                     /locus_tag="ACG8LA_001069"
     CDS             complement(10429..12471)
                     /locus_tag="ACG8LA_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFQ0203383.1"
                     /translation="MLYKLAVKSFFRQSRGYLVYFFSLTLSVMIYYSFSAMTYDQSLV
                     RRASQDTSIDGGLSFGGFIITVVLLFFVFSANRFFLNRRQKEIGIYQLFGMNKLQISG
                     IYVLEIMIIGLFACISGILLGIIFSKLFSMILVRMMDMDLTSPFFISIPSVVDTLFAF
                     FIILLAVSVYSIWKIWRYPMIRSFGEKEQADSSTMRFRTRHRLLAVIGLLLLTSGYFG
                     ASHFREITSWMISYHYLDTLVFFFPFLIFFVCVVGTYLFFCYTFRLFLIILSKWKIYY
                     YGINFLIMGNTQVHLLKSWRTNSLITVILGISLMTIGGTASISTILSYQEKVSSPMDY
                     QFDVETEKKIKPILAEEGQKITKEITLHYKVIGSIYSQNLEEPMFQTANLITETQYQA
                     FRKVNPDLPNISLKSPGHTVLLDQMQTLFRNISLYGSSIGLPDNQELKIQQMLPSVLG
                     DETMVYLSPVLIVDDTVFEKAKGVDYQVVNVDVSGGNNEKIDERLSNDLSIKWLNAVY
                     YSYDIVNGSLQGEISTKKLPDDQMKEAQFSQESSRLNFSSSYSKLRAVNRRIGINIFV
                     TLFVGMIVIIATGSILTVRQLAEAEEEKENYHLLTKLGIPQRRIRRMIFEQNALTFFP
                     PMILGITHAVFAINVFTQYIKTADYWLAYLVSGLLILIYLLLYVITSQLYCRIIEE"
     gene            complement(12461..13228)
                     /locus_tag="ACG8LA_001070"
     CDS             complement(12461..13228)
                     /locus_tag="ACG8LA_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0203384.1"
                     /translation="MEKMIEVKHLSKSYGSKLSPVKALDNISFTVEEGEFVGIMGPSG
                     AGKTTLMNILSTINLPTMGSVSIQGKEITKMKNSELSDFRRKKLGFIFQEFNLIDTLN
                     AKDNILLPLAVERMTKEEMEKRVRHVAQLLNIEELLKRYPDELSVGQRQRIAAARALV
                     VQPQVIFADEPTGSLDSKSATELLNYLKTMNQKEKATILLVTHDPYTASYCDRILFIK
                     DGVIFSEVVRRGTRREFFEKVIDMQATIGGGGKMNAV"
     gene            13554..15743
                     /gene="nrdD"
                     /locus_tag="ACG8LA_001071"
     CDS             13554..15743
                     /gene="nrdD"
                     /locus_tag="ACG8LA_001071"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008998 - ribonucleoside-triphosphate
                     reductase (thioredoxin) activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HFQ0203385.1"
                     /translation="MKVNYEEKTVVTQQPETSQMKVIKRDGRHVDFDEQKINEALIKA
                     EKKIHGSLSPLTYEKIQMIADLVVQEIKSRFAENVKIYEIQNIVEHILLEKNEYELAE
                     EYINYRTKRDFARSKATDINFSIEKLINKDQTVVNENANKDSNVFNTQRDLTAGIVGK
                     SIGLKMLPPHIANAHQKGDIHYHDLDYHPYTPMTNCCLIDFKGMLNNGFKIGNAEVES
                     PKSIQTATAQISQIIANVASSQYGGCSADRTDELLAPFAELNYKKHLKDAEEWIDSPE
                     RQKEYAKAKTKKDIFDAMQSLEYEINTLFTSNGQTPFTSLGFGLGENWFEREIQKAIL
                     QIRINGLGSEKRTAIFPKLIFTLKKGVNLNPEDPNYDIKQLALECATKRMYPDILNYD
                     KIVELTGSFKVPMGCRSFLQGWKDENGQEVNVGRMNLGVVTLNLPRIAIESKGDQNKF
                     WQLLSDRLEIMKDALLYRVERCKEAIPANAPILYMYGAFGKRLSRTDSVNELFKNRRA
                     TVSLGYIGLYEVASAFFGGEWETNPEAKAFTLDIVKELKANADAWGDEYGYHFSVYST
                     PSESLTDRFCRLDTEKFGIIENITDKEYYTNSFHYDVRKNPTPFEKLEFEKDYPKYCS
                     GGFIHYCEYPMLQQNPKALEAVWDFAYDKIGYLGTNTPIDHCYQCGFEGDFKPTERGF
                     ECPECGNHDPKTCDVVKRTCGYLGNPQARPMVHGRHKEISSRVKHMK"
     gene            16058..16660
                     /gene="nrdG"
                     /locus_tag="ACG8LA_001072"
     CDS             16058..16660
                     /gene="nrdG"
                     /locus_tag="ACG8LA_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043365 -
                     [formate-C-acetyltransferase]-activating enzyme activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HFQ0203386.1"
                     /translation="MRNPKPKEWLAKDYSQNYIADYKPFNFVDGEGVRNSLYVSGCLF
                     ACEGCFNKAAQNFRYGKPFTPELEEQIIADLRNDYVQGLTLLGGEPFLNTDVCLQVVR
                     RIRKEFGTTKDIWSWTGYTFDELLQDSEDKLELLSQIDILVDGRFELSKRDLKLQFRG
                     SSNQRIIDVQKSLESNQVVIWEKCTDATETYEQIKKQDLI"
     gene            complement(16714..17835)
                     /gene="dinB"
                     /locus_tag="ACG8LA_001073"
     CDS             complement(16714..17835)
                     /gene="dinB"
                     /locus_tag="ACG8LA_001073"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HFQ0203387.1"
                     /translation="MMELQFPLHNDTSRKIIHIDMDAFFASVEERDHPEFRGHPLVIA
                     RHPSDTGGRGVVTTANYEARKFGIHSAMSAQKAYELCPQAIFKPGDYHKYSDISKQVR
                     EVFYRYTDIVEPVSIDEAYLDVTENKINCKSAIKIARMIQADIWESVQLTCSAGVSYN
                     KFLAKLASDYQKPRGITVVAPQDAVPFLKALPIEKFHGVGKKTVPRMHELGIYTGKDL
                     YECTEMMLIRNFGKMGYSLYRKVRGIHDSPVNVTRERKSVGKEHTYGQPLQTEEAVLT
                     QLRQLAEKVEEALRRVQKHGKTVVLKVRYTDYSTVTKRVTLPEYIYKKEALFYQASLI
                     WEEILGVEKGIRLLGITLTNLDPMTYENIVLPLWENQEI"
     gene            complement(17944..18816)
                     /gene="rsmI"
                     /locus_tag="ACG8LA_001074"
     CDS             complement(17944..18816)
                     /gene="rsmI"
                     /locus_tag="ACG8LA_001074"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0000451 - rRNA 2'-O-methylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HFQ0203388.1"
                     /translation="MYNQKSFKGNPVYGDLYLVPTPIGNLEDMSYRSVRMLQESDLIA
                     SEDTRNTQKLLNHFEIHTPQKSLHEHNYKERVPQLIALLKEGKTIAQVSDAGMPSISD
                     PGHELVLACIKEGISVISIPGPTAGMTALIASGLVPQPFLFYGFLPRKKKEQKETLKK
                     LKEQTVTLIFYESPYRITATLTNFLEIFGNRQVVLCRELTKVHEEYLRGSTEELLAYI
                     EEHPVKGECCLLVEGNLFEMPVTEVDEELGTLKEQVEAKIASGEKPNAAIKAVALKNG
                     LKKQEVYRQYHELD"
     gene            complement(18885..19232)
                     /locus_tag="ACG8LA_001075"
     CDS             complement(18885..19232)
                     /locus_tag="ACG8LA_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HFQ0203389.1"
                     /translation="MDKRSLYDGLNQLESELRNTLTELVEMKHALHEIVEKNTTLEME
                     NQRLREHLRELNQVAQAPAENVKQELSKSRMNLEKIYEEGFHVCYDLYGSRRDNDEPC
                     AFCLEVIYRESGR"
     gene            complement(19225..20049)
                     /locus_tag="ACG8LA_001076"
     CDS             complement(19225..20049)
                     /locus_tag="ACG8LA_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage 0 sporulation family protein"
                     /protein_id="HFQ0203390.1"
                     /translation="MVEVVGVRYRDAGHIYYFAPGDSEYVYSDKVLVESQQSLHIATV
                     VLPKKEIDPNDLPEAIRPILHKASQAELEKDKKNKKDAYDALKIAKEKVQLRELEMKM
                     VKAEYTFDRNKLIFSFTADGRIDFRELVKDLAAVFRTRIELRQIGVRDEAKIIGGIGP
                     CGRPLCCSSFLGDFVPVSIKMAKDQSLSLNPTKISGLCGRLMCCLQYESEEYETAKKE
                     LPDFGKVIATPDGKGKVVGLNLLSRIVSIRLTGRENPVEYEWDELKEFIQVGEMNG"
     gene            complement(20085..21023)
                     /gene="holB"
                     /locus_tag="ACG8LA_001077"
     CDS             complement(20085..21023)
                     /gene="holB"
                     /locus_tag="ACG8LA_001077"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HFQ0203391.1"
                     /translation="MNQEINLAQMQPIVYQQLQRSFEHGRIAHAYLFEGEKGTGKHEV
                     GIWLAQHLFCTQMKDNLPCGKCNNCQRIEKKEHPDVLVIEPEGQTIKVDQIRRLQTEF
                     SRSGYESRKKVFLIKEAEKMNSSAANSLLKFLEEPPGDFLAVLETDAVGRILPTIQSR
                     CQVLHFQELSKEALIHRLQEEQIPLEKAKLLAFLTNSLGKAVEISQDEWFNDAKDLIY
                     QWFVYLQKQDTQAFIYVQKKLVKSFKEKTQQFTGLSVLMFYYQEAQRQAVANGEYGKV
                     KQINQIIERILIAEQKLRSNVSFQAVAEQFVLHTIF"
     gene            complement(21037..21366)
                     /locus_tag="ACG8LA_001078"
     CDS             complement(21037..21366)
                     /locus_tag="ACG8LA_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-di-AMP receptor"
                     /protein_id="HFQ0203392.1"
                     /translation="MKIILAIIQDKDSNRLSNELIDANIRATKLSSTGGFLKAGNSTF
                     IVGIEDDRVEEALEIIKKTCESRKQFVSTPVTLDISMDGGVPYPVEVEVGGATVFVLP
                     VEGFHQF"
     gene            complement(21381..22025)
                     /gene="tmk"
                     /locus_tag="ACG8LA_001079"
     CDS             complement(21381..22025)
                     /gene="tmk"
                     /locus_tag="ACG8LA_001079"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004798 - thymidylate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006233 - dTDP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HFQ0203393.1"
                     /translation="MNGLFITIEGPDGAGKTSILNELYPLLKEVAKTEIIQTREPGGI
                     PIAEEIRAVILDPKNDRMDERTEALLYAAARRQHLVEKVLPALAKGKIVLCDRFVDSS
                     LAYQGAGRRIGVTEIARLNEFATEGTTPDFTLYLDVDSDTGLRRIKKNRQNQIDRLDS
                     EGLEFHQRVRHAYLKLAEENPERIHKVDARKSFEEVLQTSYHTIIEQYPQFFEN"
     gene            complement(22089..22685)
                     /gene="recR"
                     /locus_tag="ACG8LA_001080"
     CDS             complement(22089..22685)
                     /gene="recR"
                     /locus_tag="ACG8LA_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombination mediator RecR"
                     /protein_id="HFQ0203394.1"
                     /translation="MQYPEPIAKLIDSYMKLPGIGQKTATRLAFYTIDMKDEVVNEFA
                     KSLLSVKRDLHFCSICGNITEEDPCEICRNPSRDRSVILVVEEPKDVMAMEKMREYHG
                     LYHVLHGVLSPMEGTGPEDINISSLLQRLHDADVKEVIIATNATTEGEATAMYLSRLI
                     KPAGIKVTRLAHGLSVGSDIEYADEVTLLKAVEGRREL"
     gene            complement(22710..23024)
                     /locus_tag="ACG8LA_001081"
     CDS             complement(22710..23024)
                     /locus_tag="ACG8LA_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HFQ0203395.1"
                     /translation="MMRGMGNMQGMMKQVQKMQKEMAEAQELLNKTEFTGKATNELVK
                     AVFTGDRRMKDIQINEEVVDPDDIEMLQDLVVMAVNDAIAQIDVETEKKLGKYAKGLP
                     GF"
     gene            complement(23044..24789)
                     /gene="dnaX"
                     /locus_tag="ACG8LA_001082"
     CDS             complement(23044..24789)
                     /gene="dnaX"
                     /locus_tag="ACG8LA_001082"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009360 - DNA polymerase III complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HFQ0203396.1"
                     /translation="MAYQALYRVWRSQRFEDIVGQKAVTQTLKNAIVSHKTSHAYLFT
                     GPRGTGKTSAAKIFAKAINCPNSKDGEPCNECEMCRSITAGTQEDVIEIDAASNNGVE
                     EIRFIRDRANYAPTKAAYKVYIIDEVHMLSTGAFNALLKTLEEPKESVIFILATTEPH
                     KIPATIISRTQRFDFKRINTADIVEHLEFILKESTISYEPAALNVIARSAEGGMRDAL
                     SILDQAISFSEGTITLDDAMQVTGSLTDEMMDSYLSACVKKEVPEALETLNQILAAGK
                     ESRRFLEDMLQYCRDLLMYQQAPNLVEEQSSTIRSTFTELAQTVSADQLFSMIKILSD
                     TQNEIRFTNSAAIYLEVATVKLAQLPSASVPSADVAFADDQIVKQLQQEIKELRNEIK
                     ELRSNTGIENTKVQPVQQTNHKKQTSTYRVPTERVYKVLREATRQHLNQVKEVWEDLL
                     MSLSVTQRAMLKASEPVAAGPTGLVIAFDYEIVCQRAANDEELQLSVHNNLSRMIKDY
                     APDPVYITRESWPELRRNYLTQAQEEGTENSFASEDSEGEIELLPQEQEVPEETLVVK
                     AEELFGSEAVTVVDD"
     gene            25004..26251
                     /locus_tag="ACG8LA_001083"
     CDS             25004..26251
                     /locus_tag="ACG8LA_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HFQ0203397.1"
                     /translation="MGLIKAATSMVGGGLADQWLEVIEPDNMSDTTVMTKGVKVRKDD
                     KRGSNRKGTEDVLTDGTVVHVYPNMMMLLVDGGKIIDYTAEEGYYTIKNDAAPSMFNG
                     TLKEAIAETFDRFKFGGVTPQKQQVFYINLQEIKGIKFGTSAPLNYFDNFYNAELFLR
                     AHGTYSIHVVDPILFYTNAIPKNKTQVEINDINEQYLAEFLTALQSAINQMSADGQRI
                     SYVPSKSLELSKYMDTALDDSWRELRGMEIVSVAVASISYTDDSVKLINMRNEGAMLG
                     DPSVREGYVQGSIARGMEAAGKNEAGAMTGFMGVGMGMNANGSYLSQAAQNNQEQIKQ
                     QAEKQNQQTAQGNADTWTCPVCGTENSGKFCSNCGAAKPVENVQPKLQMRCSECNEIV
                     DLSNGIPKFCPNCGKPFKGIPVN"
     gene            26276..27460
                     /locus_tag="ACG8LA_001084"
     CDS             26276..27460
                     /locus_tag="ACG8LA_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HFQ0203398.1"
                     /translation="MDVLTHKCPNCGGPLTFDPKDQKFHCEYCLNIYTEEEVSQYEQK
                     QKEARMAGEESKEEPSPTEDFTFTAQEQLADMNEAERKAVDEAGGFSDTADESADNTA
                     AIDLFLCPNCGAEIVTDATTAATYCYYCHNPVVLSGRLSGEFLPNKVLPFAVEKEEAI
                     NRFLAWTKKKWFVPKAFFNKDQIDKLTGVYFPYWATDAEVDGAMQANGTVIRIWRIGD
                     IEYTETKQFAVSRAGKLSFKELVKNALSKNTQQKMVEGVQPFPLDKAIDFKSQYLAGF
                     QAEKRDIEYEAIKSQIQSELKDYSEKLLKDTANGYTTLTGVRTSASITNEVNNYVLLP
                     VWLVTYRSNDSSKKVYYYAMNGQTGKVSGVLPISQKKLGLTALGIFAGLAILFLIGGY
                     LI"
     gene            27457..28254
                     /locus_tag="ACG8LA_001085"
     CDS             27457..28254
                     /locus_tag="ACG8LA_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TPM domain-containing protein"
                     /protein_id="HFQ0203399.1"
                     /translation="MMKKFFLFFLLLVSVGWPVATHADTATVNDEAGLFTTDQIQSLE
                     QQAEKLNEKIKGRVLIVTTTSNSEEPRDFADNYLRDAVGNDQNGSVLLLDMGQREIYI
                     STSGNMIDYLTDSRIDSILDDVYDQMTNAAYYNAAKAYLSKSATYVEDGVPGGHYRVD
                     EETGKITRYKVLTTVEIIIAVVLALILSLVFYFVTVSRYQLKSGIYKYPFREKSSIKL
                     TEKTDRLTNSFVTTRRIPKSPPPGSGGGGSTTHSSGGGTFGGGGRSF"
     gene            complement(28696..29352)
                     /locus_tag="ACG8LA_001086"
     CDS             complement(28696..29352)
                     /locus_tag="ACG8LA_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HFQ0203400.1"
                     /translation="MDSRVLKEYLDKNDFPIIRKGYHKYLTFEGMEDSHTYILKEGTV
                     KASVISNDGREFNLRYIKDLEIVSLLKDEYSQFIDSPYNIRVESEYAEFYRINRVRFW
                     QNINQDPKLQHYVKEYYRYRLLYSMKKMQQMLLNGKLGAVCTQLYELYDLFGVRTEEG
                     MLIDFSITNEEIAKFCGISTASSVNRILKQLKKDGIITVKDHHIVILNMDLLEDNIIF
                     "
     gene            29545..29823
                     /locus_tag="ACG8LA_001087"
     CDS             29545..29823
                     /locus_tag="ACG8LA_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0203401.1"
                     /translation="MNYWMNTIINRLETAYQTRFDMKASLVFLNDAYQNSIELIKAVD
                     ENPTNECEEFLNLFMSTRDLFIRQLVDRYPSNYHDVEVQIQKLKAYSA"
     gene            29842..31050
                     /locus_tag="ACG8LA_001088"
     CDS             29842..31050
                     /locus_tag="ACG8LA_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFQ0203402.1"
                     /translation="MEKKLFNKYFIGITLINFIVYLIYYLLMVIMAVIAQDTLHASLS
                     QAGFASGIYIIGTLLARLFMGKQLELFGRKFTLRGGAIFYLLSTLAYLYTPTIGALYL
                     VRFLNGFGYGTVSTATNAIVTAYIPASKKGEGINYYGLSTSLAAAVGPFLGMILLNMT
                     DFRFIIWFSIVLVFFVTIACLVFPVKNIPLSEEQKISLRSWNINSFIEKKALFITGIA
                     FLMGLSYSSVLSFLSSYTKVIHLVAAGSFFFVVYALVITFTRPLTGRIFDVKGEQYVM
                     YPSYLFLTAGLFLLSVTTNSVTLLISGALVGLGYGTFMSNGQAVCLKIVREHRISIAL
                     STYFIGLDLGLGVGPYLMGMLKSLTSFRGLYVIAGVIPLICTALYLVNGRKHSHEAEG
                     ELIESLKNEI"
     gene            complement(31198..31563)
                     /locus_tag="ACG8LA_001089"
     CDS             complement(31198..31563)
                     /locus_tag="ACG8LA_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2512 family protein"
                     /protein_id="HFQ0203403.1"
                     /translation="MKHVKALVVKAIMIWAILWVVLTGLYGVSFMDSTIVGVIIVVMI
                     YVLGDLLILRKVGNIAATIADAGSAAVILWLYLYFMNDTVDIWMKVLIPALLIGVAEW
                     FFHKWLLSQGIVPDERKME"
     gene            complement(31710..32483)
                     /locus_tag="ACG8LA_001090"
     CDS             complement(31710..32483)
                     /locus_tag="ACG8LA_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HFQ0203404.1"
                     /translation="MLNEVENRQQEIVNYLKNNQFARVTDLIELVNYSEATIKRDLVF
                     LEKSGLIRRVRGGAMLIDNRKIDVPYLMKITKLEEETEKRKIADTASSLIRDDMVLFL
                     DSSTTSLHLVRNLARFDGLQIITNGIVTAAMLSEYTTAKVSVLGGAIVPKRATINGSK
                     AYNDALSYYADLAIMSCRGLDFSQGVTETHEGEAMVKKAFRKQSDRLAVLVTQQKIAH
                     KFMHQAIAFHEIDYLVTSKELTKEQYAKVKEHHIECLYG"
     gene            complement(32657..33517)
                     /locus_tag="ACG8LA_001091"
     CDS             complement(32657..33517)
                     /locus_tag="ACG8LA_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HFQ0203405.1"
                     /translation="MLYTMKELLKVAKENQFAVPAFNICSYDMMKAIIEEAERLEAPV
                     ILEIHPDEIAYLSDEFVAAVRAYAYTSKLPIVIHLDHGGTIEDVLRAIRNGYSSVMID
                     ASLKSFDDNVQITKKVVALAHAVNVSVEAELGTIGNNGSAEGGAETIIYTDPDQAKIF
                     VKETGIDTLAVAIGTAHGLYPKNRTPKLNIDLLKELNQQIDLPFVLHGGSGNPDAEVS
                     EAVKYGVAKVNLSSDLKSVFFNALREILSENPSMYEPNAIYPAANKKVQEVVKHKMEI
                     LNTVGKASLY"
     gene            complement(33517..34935)
                     /locus_tag="ACG8LA_001092"
     CDS             complement(33517..34935)
                     /locus_tag="ACG8LA_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HFQ0203406.1"
                     /translation="MKIVGVTACPTGIAHTYMSAEKLEVTARNLNHQAKFETQGVKTE
                     NQLSEQEIKEADAIILAVDKEIELDRFAGKKVKRVSTSRAIKEPQVVIDEALRDIGVF
                     VVSNEKEPAANEKKPTIYNHFMNGVNYMLPFVIAGGIIIALSFAFGITAADPNSADYN
                     VLAAAFSRIGGDTAFAMMVPALGAGIATSIAGKAGFAPGIVAGLLASTGGSGFLGGMI
                     GGVLAGYICDFLANKISVKKEFSAIYQLIVVPFLSILIIGLLMVFVIEQPITWVLDAL
                     TNWLNSLGNTSGLLFGLLIGIMMAADMGGPINKSTSTFSIGLMSAGVNAPIAACMAAG
                     MTPPLGIALATLLFKHKFTKEERTSGQSCWILGASYITEGAIPFAVSDPIRVIPSLMT
                     GSAVAAGISMAVGVTSMAPHGGIWVMLIPNVMNNLPMYVLAIASGTVTTAFMLGLLKK
                     TVKEKKQDKWTKNENLTNEVEA"
     gene            complement(34992..35441)
                     /locus_tag="ACG8LA_001093"
     CDS             complement(34992..35441)
                     /locus_tag="ACG8LA_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFQ0203407.1"
                     /translation="MRFDQLIAEELIVFDPSIDSKGSLFERIGDVLKKTNKVRNVQKV
                     VKALFKREEEISTGIEDGFGIPHAKSKYVTKPALCFFHTAKLTDYSGIDEMPIEYIFA
                     IVVPEKSADMHLEILSTLSRRLMNADFRKGIKEATTPADIIRQISQE"
     gene            complement(35886..36149)
                     /locus_tag="ACG8LA_001094"
     CDS             complement(35886..36149)
                     /locus_tag="ACG8LA_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HFQ0203408.1"
                     /translation="MKENIHPDYHPVVFMDSTTGFKFLSGSTKTSQETVEWEDGNTYP
                     VIRVEVTSDSHPFYTGRQKFTQADGRVDRFNKKYGLKDANAAE"
     gene            complement(36248..37543)
                     /gene="rho"
                     /locus_tag="ACG8LA_001095"
     CDS             complement(36248..37543)
                     /gene="rho"
                     /locus_tag="ACG8LA_001095"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008186 - ATP-dependent activity, acting
                     on RNA [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HFQ0203409.1"
                     /translation="MSDYLTMAELENKTLKEVYSYAKEFKIPYYSKMNKKELSLAVIR
                     AQAEKQGFYYMEGILDIVGQDGYGFLRPINYGPSAEDIYISASQIRRFSLRNGDKVAG
                     KARPPKESERYYGLMHVESVNGKDPEEAKERPHFPALTPLYPQRQLQLETTPQRLSTR
                     MIDIFSPIGFGQRGLIVAPPKAGKTSVLKEIANGITENYPEVELIVLLIDERPEEVTD
                     LERSVKGDVVSSTFDLQPQNHTRVSELVLERAMRLVEDKRDVVILMDSITRLARAYNL
                     VVPPSGRTLSGGIDPAALYKPKKFFGAARNIEEGGSLTILATALVDTGSRMDDVIYEE
                     FKGTGNLELQLSRELSERRIFPAIDIKKSGTRKEELLMPSEELEEIWKLRKNMTGDSL
                     EYTEQLIRFLRKTKNNQQFFKEFQDVSFGKKNPTRNLKR"
     gene            complement(37540..38811)
                     /locus_tag="ACG8LA_001096"
     CDS             complement(37540..38811)
                     /locus_tag="ACG8LA_001096"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008760 - UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0019277 - UDP-N-acetylgalactosamine
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HFQ0203410.1"
                     /translation="MKKIVIKGNRPLAGEVTISGAKNSAVALIPAAILADSPVILEGV
                     PDIQDVHSLIEILEIMGATVHFSNNILEIDPREVVSIPMPHGKINSLRASYYFMGTLL
                     GKFGEAVVGLPGGCYLGPRPIDLHVKGFEALGAEVTNEHGAMYLRTENKGLRGNRIFM
                     DVVSVGATINVMLAAVKAKGQTVIENAAREPEIIDVATLLNNMGAKVRGAGTDVIRIE
                     GVETLHGCRHFMIPDRIEAGTYLALAAAVGNGIKVKNVIFEHLESFIAKLQEIGVHMK
                     ISEDEIEVYPSKELKPANIMTYPYPGFATDLQQPLTALLLMTTGTSEIIDTIYAKRVN
                     HVPELARMGADITVEGNMIIVNGPNKLHGTEVVASDLRAGACLVIAGLLAEGTTTIYN
                     VDYILRGYDHIIEKLTALGASIEMIEEVGAE"
     gene            complement(38977..39846)
                     /locus_tag="ACG8LA_001097"
     CDS             complement(38977..39846)
                     /locus_tag="ACG8LA_001097"
                     /EC_number="4.1.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010753191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004332 - fructose-bisphosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase"
                     /protein_id="HFQ0203411.1"
                     /translation="MPVVSGAEFLKAARKGGYAVGGFNTNNLEWTQAILEAAEAKQAP
                     VLIQTSMGAAKYMGGYKICKDLITDLVEAMNITVPVAIHLDHGDYEAALECIELGYTS
                     VMFDGSHLPFEENLKLAKDVVEKAHAKGISVECEVGSIGGEEDGIIGNGELADIEECK
                     QMVATGIDYLACGIGNIHGQYPENWKGLAFDHLQAIADAVGPDMPLVLHGGSGIPQDQ
                     IEKAISMGISKVNVNTEFQLSFAAATRKYIEAGKDKEGKGFDPRKLLAPGKAAIVEDA
                     KSHIDWFGSANKA"
     gene            39949..40161
                     /locus_tag="ACG8LA_001098"
     CDS             39949..40161
                     /locus_tag="ACG8LA_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0203412.1"
                     /translation="MKMKIFKKFFAKNKISNSALIEKSLLLSIFFPTNNNKSEKEKSD
                     KKIAYPLLLLLFSFYQVQKLFCFVIC"
     gene            complement(40138..41748)
                     /locus_tag="ACG8LA_001099"
     CDS             complement(40138..41748)
                     /locus_tag="ACG8LA_001099"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003883 - CTP synthase activity [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0006241 - CTP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HFQ0203413.1"
                     /translation="MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYI
                     NVDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRKE
                     RKGEYLGATVQVIPHITNEIKEKIMRAAKMTDSDVIITEVGGTVGDIESLPFLEALRQ
                     MKADVGTDNVMYIHTTLIPYLKAAGEMKTKPTQHSVKELRGLGIQPNILVVRTEQPVS
                     QSVKNKLAQFCDVEPEAVIESPDVDTLYSIPLVLQAQGMDQIVCDHLKLDTPEADMTE
                     WKELEERVLNLKKKVRIALVGKYVELPDAYISVVEALKHSGFAYNSDIEIDWIKAQEL
                     TRENVEERLKDADGILVPGGFGDRGVEGKIEAIRYARENDVPFLGICLGMQMACVEFA
                     RNVVGLEDASSAETNPDTANNIIDLMADQENIENLGGTLRLGLYPCKIKKGTKTAEAY
                     DGADVVQERHRHRYEFNNKYRQLFEEQGLVFSGVSPDNRLVEIVELPEKKFFVGCQFH
                     PELISRPNRPQKLIKAFVGASLADHETK"
     gene            complement(41970..42215)
                     /locus_tag="ACG8LA_001100"
     CDS             complement(41970..42215)
                     /locus_tag="ACG8LA_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0203414.1"
                     /translation="MKEKDCFYDKLYKLLLQVGKSSSLLGGILSIIMFVLFFYLLFHL
                     KFFSNDFLICLGLTLAMFISSLLCGLNFFCTHKGLKK"
     gene            complement(42941..44281)
                     /gene="glnA"
                     /locus_tag="ACG8LA_001101"
     CDS             complement(42941..44281)
                     /gene="glnA"
                     /locus_tag="ACG8LA_001101"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004356 - glutamine synthetase activity
                     [Evidence IEA];
                     GO_process: GO:0006542 - glutamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HFQ0203415.1"
                     /translation="MVKKQITGEEIKRIIEEENVRFLRLMFTDILGTIKNVEVPVSQI
                     DKVLENKMMFDGSSIEGFVRIEESDMYLYPDLSTWMIFPWESAHGKVARLICDIYNPD
                     GTPFAGDPRGNLKRALKDMRDLGFTSFNLGPEPEFFLFKLDEDGGITTTLNDKGGYFD
                     FAPTDLGENCRRDIVLELESLGFEVEASHHEVAPGQHEIDFKYADVVDACDNIQTFKL
                     VVKTIARKHGLHATFMPKPLFGINGSGMHCNMSLFNDEGNVFYDKDGELELSETAYHF
                     LGGLLKHARAYTAVCNPTVNSYKRLVPGYEAPVYVAWSGRNRSPLVRVPESRGLSTRL
                     ELRSVDPSANPYLAMAVLLQAGLDGIRNQITPPAAVDRNIYVMDEEEREAAHIQDLPS
                     TIHNAIKELRKDNVMIDALGQHIFSNFVEAKRLEWAAFRQTVSEWEREQYLELY"
     gene            complement(44309..44701)
                     /locus_tag="ACG8LA_001102"
     CDS             complement(44309..44701)
                     /locus_tag="ACG8LA_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HFQ0203416.1"
                     /translation="MGEKELRRSMSVFPIGTVMKLTDLSARQIRYYEEQDLVHPERSE
                     GNRRMYSLNDIDMLLEIKDYLSEGLNMAGIKRVYEMAQAKKQEAKNKKPLTDHDVRQI
                     FRDEILAQGGLSKTGHYQSQGLQRQFFD"
BASE COUNT        13297 a         9346 c         7831 g        14438 t
ORIGIN      
        1 atatataata aaaaagaatc tttttattta cgtataaagt ggagcataat cattatatta
       61 tcattgttat ttttaacagg aattgcttat ttcttttatt ttattttttc tcctgcggac
      121 agcaatcaaa tgaaagaaat aaaagattcg tgggttttct atacaaaaga tgatcctgat
      181 tttaagtttg acagcaagta cactcgtacg attcctaccg tggataaaga cgaaacattc
      241 attatggaaa cgacacttga aaaaccgttg gacgaagcaa atttactaat caaaggaaac
      301 catcaatgga ttactgtata tctaggcgaa aagattttat accaacggaa agattatcag
      361 gaagaaagca atcccggact ctcattggct gtgatagatt taccagcaaa ttatatcgga
      421 aaaaaattga cccttacagt ctcatctcct tatcagaact atgctggact gccaccgaaa
      481 gtttatctag gaacaactgg accattgatt agttttattt attcacaatc agtgccgcaa
      541 gtattgacga tgataatcgc tgtttttatc gctataggga cctttttcta tacgatctac
      601 ttgatgtata aacaaaaacg tcttgaatac tcacttattc tcttaagttg ctttgctttg
      661 gcattaggat ttgaagctgt atcagaagat attttaagtg gtattctttt tgaaccattc
      721 gttcattctt ttttatctca tttatttatt atcttaacgt cagctttcat catctgctac
      781 tattggagcc gaatgtttta ctataaaaaa tggtacggaa ttttttgtac gttccaactt
      841 ttgattttta tcggcgttct gctttatgca acttttactc ctgcagaact tcctgaatta
      901 atgccgattg ctaatattgc tagtgttata agcactttag tcacttcact tgcatgcatt
      961 ggcgaagcat ataagaataa ccgtttttat gtagcttgta caccttggat cgtcttggta
     1021 gccattatcc attgcttgat ttacatccaa acggcattag gtatctatca aacaacgatc
     1081 aattggtcta cgattttata tattatcatt ctaatcgtta ttatcagcta caatctaatc
     1141 gatcacatct taaataccga caaagatcgg agacaagtag atttcttaaa aatcaaaaat
     1201 gatttgttgg agcaacatta tgagcagctt cgacagcata tccaagaagt aaatacactt
     1261 cgcctggaat ttgtccaaga gatggagaat ctgcaagatt taatgcatac ggaccaaaca
     1321 aaagctaaaa actatgtgga aaagatatta gaagaagcaa aaaatttcga aatgctgtgt
     1381 tctttttgca accaccaggt gacaaatctt atcttagcgc gttaccagaa gttagctgcc
     1441 aaacggaata ttcagataac cttccaagca gatcttcccg aagaacttcc tatcaacgat
     1501 gacgatctgg ctcaactttt gatccacgct ttagagcatt cctttagaga aactcatgcc
     1561 atcgaaaatc cactgtatcg aaaaatttat ttgtcgatac acgaacaaga ggaacatttc
     1621 gtcatttgtt gcgaacatag tgcacattac gatacaaacc tatttagtcg aggcatcaca
     1681 gaagaattag atgatcagga acgttttgac ttaatgatga tgaaagacgt agcggatcgt
     1741 tacacaggaa cactaacgca ggaaaaagat actttcattg atcggatcac tgttcaactc
     1801 tctcgaaatt acccgaatcc tgtataaaaa atagcggaat ccatatatgt ggattccgct
     1861 attttttatt ttcaataaag taaggtaagc aattcttctg gttctatcgc accaaaatat
     1921 ttcttcacat caatttggct gactattttt gatagagatg ctttatcata tttctgtcca
     1981 accaattttt tttccacgtc agagatatct cctagtccga agaaatcgcc aaagattttt
     2041 gcttctttga tcattccttc tgagacattc aaatggactt caatcgaacc gatagaaaaa
     2101 cgtttttggc gagagaaatt gaaatctgga gacttcccgt aattccaatc ccaatttcga
     2161 taatattcct cagagattcg attgattttt ttccaatctt catcagtcaa ttcgtacgtt
     2221 tttacttctt ctactgactc tacgccgaaa attttcaaca agatttcttg acgaaattct
     2281 tctgttgtca ttttttgctt ttcttctgga agaaatggtt tgatattcgt tacacgagaa
     2341 cggatcgatt tgattccttt tgattcgatt ttgtcttttt ttacttttaa tgcattgact
     2401 acttcattga tatcagagtc gaacataatt gttccatgag caaacatccg accgttggta
     2461 gcatacatcg cgttgccaga aaatttcatg ccatcaatga ctagatcatt tcggcctttc
     2521 aattccgccc cagcaacacc caattcatga agtgcttgga tgattggctg tgttactttc
     2581 gcaaagtcac ggaatgaatc cccatcatca ggcatgataa aactaaagtt caggtttcca
     2641 aaatcatggt agacagctcc gcctccactt aagcgacgga caacatgaat gccattttct
     2701 tccacataat ctcgattgat ttcttcaagc gtattttggt ttctgccgat gatgattgaa
     2761 ggttcattga tataaaagag caaaataggt tcatctaaag gcatttcttg cagcaaatat
     2821 tgttcaattg ctaaattgat tcttgggtcg tggttttcat ttggtacaaa aatcatgttc
     2881 ttcctcctaa atgttaaaca ctttgtcaac tgcagcaagt tctatatcaa tccctttgcc
     2941 tgctgccttt tgcgcttcat ttttcaattg ttctaaatca ccaaactgag gtaggtgtgt
     3001 aagtacaagt ttctttacgt tagctgattt cgcaagttct ccagcttctt ttgaagtgaa
     3061 atgggcatga tgatgttcat ttccttcaaa aagataggta tctgctagaa acaaatcagc
     3121 atctttcgca aaatcagcga aactttccaa ataacctgaa tcacctgtaa atacgaatac
     3181 tttccccgtt gtttcttcta cgatacgcat ggcgtaacat actactggat ggattgtttc
     3241 cataaaagta atcagaaaag gaccaatttt taattcttca gcttcaaaat aaggatgtcc
     3301 ttttgagaca ttttccaacg tcaattcttc aaagtgaatg gaatcttttg tgtgtccata
     3361 aattgaaagc aatgtctccg gatttctctt aggatgaagt tgccagtaat actgtaatac
     3421 accaaggtca gcaatatgat catgatgata atggctaagg atcacagcat ctagatcaag
     3481 tggatcaagg tgttcttgta atttgatcag cgtagcacta cctgcatcga tcaacaaatt
     3541 gaacccgtca gattgaagca aataacctgt tgtcccttga tttttataag gatacgctcc
     3601 taagcatcct aaaacagtta atttcatcgt acattccccc tcaaagattt atcctaccac
     3661 aaaagttatt tttttgatga ataaactgct tacatgctaa gtaaaatagg cgtctggacc
     3721 tcctttttca atccgtgctt gttcataaaa ttctgcaact gacacattca cataaacaat
     3781 gacccacaaa agaccgatga acaaagcgat tgctcctagc aaataccagc cgataaaaga
     3841 cagctgcaac aaaatatacg taccaattct atctttcaat aaaaaccagc catatttcaa
     3901 acattgaata accgacaaat caggatagtc gaactttgtc catgcagcaa attggaataa
     3961 accgccaaca atactcatga tgagtgctga aacaaaaatc atccctatca tcgataaaac
     4021 aaagctgata tcaagaaaat cttctggcat gacacccgta ggtaccgcat ttgaactgaa
     4081 aagcagctgc atataagtac tcactccgct gattaaaaac atgggcagaa agattaaact
     4141 gttgagtagc cagttgatga ctgaattgat caaattgatg ccaagtatcg aaccaaaata
     4201 ctttctttgg aaaactgaaa ataaaaggtt actttttggt ctgccacccc gtacaactac
     4261 tagcgcaatg taaaacaatg catagttgaa tgcgaataaa agtaaattat cgactagaaa
     4321 actcaataag tgctgctgca tgctttcttc cggaaaagga ctgaaaccgt caaaaaagtt
     4381 ctggatgacg ctcgtaaata ttatagataa gaaaacaagc caagtattga ttccccattg
     4441 attttccaaa gaaactcgtg cttttttccg atattcagaa ataggtattc tattattcat
     4501 tattcataac tccgaatttt ttcaactgtt tcactatcaa gccgtttcac taattctgtg
     4561 actagtttca ctgtattcaa ataatcatct tcatgaatca ctgatgtatg ggaatgcaga
     4621 taacgaacag gaacggtaat ggctacagac ggaacaccat ctcttgtcaa atgcatttgt
     4681 cctgcatcag ttcctccgcc agaaatcact gtatattgga atggaatatc catttcctct
     4741 gctacatcaa taacaaaatt caataatttt ttatgcggga tcatagatgc atcaaaaatc
     4801 aaaatctgtg ggccttttcc taaaatcgaa tctgcttctt ttggtgtcat tcctggagtg
     4861 tctcctgctg taccagtatc taaagcaaaa gcaatatcgg gatttacaag gtgtgtactt
     4921 gttcgagcac ctcgcaagcc tacttcttct tgcacatcgc ttcctgcgaa taaaacattt
     4981 gggtgtgctt ctttagatag attctctaat actcgcagag aaacagctgt cccgatacga
     5041 ttatcccatg cttttgccag taaatattta ctgccattca ttcgtttgta ttcaatatat
     5101 ggagtgacca tatctccagg acgtatgccc cactctttgg cttcttcttg gcttgatgcg
     5161 ccaatatcaa tgaacatatc ctttatttca taaggtttat ttcttacttg aggtgttaaa
     5221 acatgtggtg gtttggaacc aatcacaccg tggacgattt tcccttcacg tgttttgatt
     5281 tcaacttgct gagcaagcat gacttgcccc caccaacctc caagagtttg gaattccaag
     5341 aatccttttt cggttatttt tgttaccata aaaccaactt cgtccatatg tccagaaata
     5401 aagaccttgg ggcctccgcc agcaccatgt ttggcaatca cactgcctaa accgtcataa
     5461 aaaatatcat cagcgaatgg tttggcatat tctctgaata cttctcttac ctcttcttca
     5521 tttccaggta ctccttttgc agaagttaaa tcaataagta gctgttcttc ttttgtatcc
     5581 aaatgttttc ccccatttct atattcatat tgtgattata ccattgctta tgatttttgt
     5641 tcaggcaaac ttggtatttt tatcttttat tcagaatatt caaaaataaa gaaaacaagc
     5701 gagcaacact cgcctgtttt ctttatttta attgtagttt atctggtatt tgatgttgcc
     5761 aagatttgct aaaaaaagca tcgtcaagat gatacttact agcagtaata tgattttctt
     5821 ctaaaaacgg tctgatctgt tgatctgcag ccaaccagcc tttccagcct agatggatcg
     5881 tgtcttccat aaaatagttg gtacccgctt gattgacaaa atcagctatt cgattgaatc
     5941 cttggctatt taattgaaat ttgatctttt tggcaaatcc ttgtaacatt tcttgagata
     6001 gtccggtata atcgctccat ttctcgttaa ccggtgggat gatgaacaat acttcgttat
     6061 ggttttttgc taattgatcc aagaccagct gaaaatcaga aaattctggc gaaaaacgat
     6121 aatcccaatt tttttgtgac tgtttgagct ctggctcgtg ggctcggata cgatgcgtat
     6181 aaaaatcgtt tttcaacccg aatggattat tcgtcgtttc tcgttctcca atttgatttg
     6241 ctaaaatgga taattctgtt tcttggtatt gttttggtaa tcgttttgac tcatgatcga
     6301 ttttttgctg tcgatctttc aacccaatat tgctgaatac ttcatcctct ctcttcagca
     6361 tgttccattg gctgcgcagc tgattcaaag attcaggtaa aggtagcttc ccttttttga
     6421 tcgtttgcag aatcgccgtc aacgtatcat tctcttttac ttttgagaaa gttaataatc
     6481 ttctagctaa atagcgatca gcaggcgtta ctttcttcat tgaaaacaac cagtcgtatg
     6541 tttgaagttc agaataatac gtattaaagt aatcagtttt tacaccattt ttaacgaacc
     6601 actgaggaga aataataaag acgactttct tgtttttcat agcatctcct gcagaacgca
     6661 tcatcatata ttggcttaac gattgtgtcc cgggtgctcc cagcaaaaat ggacgatagt
     6721 ttcgctggta tttttctgcc agaacagacg gatgaaatgg actgattctg cttaattcac
     6781 ttgagccaaa aaaaggaata tattgttttt cagataatgc ataatttttt atcgcatctc
     6841 ctttcaacac gttcactgac atggaagaag aggcacgtct aatcgtttct ggattagaga
     6901 tatctacttg ataggaggag gtaaaaaaca caaacagtaa gccaacagct aaaacaaccg
     6961 ggccgaaaat agcaaaaagt ttctttttca tactcaaccc ttcaatgcag ttgcttgttg
     7021 aatgatttta ttcggtgtgc accaatcctc tcgctcgaat tcagatacag ggacttggat
     7081 atccagctct ccgtctagct cgactaataa ttgaacagat gctaaagaat caagcaaccc
     7141 ttcatcaaat agatcaatat cacgattttt tcttacttca tctgttcctg ttatttcttc
     7201 taagattgat aaaatttgtt cttccatttt ccttttctcc tttgttatat aaattaatat
     7261 gtcactattc gttagctaaa aaaaagttta tctaaaaatc ctgaaaaaat caggaagcta
     7321 aaacatactg cttgaaatgt caaaaatacg gctaagccat gcgtaaattt gttagaaggc
     7381 aactgctctt tatgcttctt cttaaatcgg atccatgcat ctgtcagaca gatcagacaa
     7441 gcatgataca gtccatatac gatgtagtac cacgtcaatc catgccatat acccattaga
     7501 agaaacaaag caaaataacc gatatttgac attacgatct tgcttttaaa aaattttttc
     7561 ttcatcatga agaacatcaa tcgcatatat acataatcac ggaaccaaaa ggacagcgtc
     7621 atatgccaac gattccagaa ttctttgata ttccatgata aaaaaggttt attgaaattg
     7681 attggtgtct gatatcccat catgtagctt gtaccgactg caaataagct atagccagca
     7741 aaatcaaaaa acaaatacat actgtacacg tacatataac ctactaatgc ccatgaaata
     7801 ccaccatgct gtaaggcaat gcgtcccact acaggaagca gtacttgacc aaaataataa
     7861 ccgataatga atttatataa aaaaccgaca aaaatatttt ggacgccttt tcccaaaaga
     7921 tcaacatatt tatcacgaac aggcggatgg agctgatctt tttcaaatct cctatagcga
     7981 tcgattggtc cagaagagat tgttggaaag aacagcagaa actggatata acgaaatggc
     8041 ttatatgttt tgatcatgcc atctcttatt tccatgatca tttgtacaga tttaaaggtt
     8101 aaataagaga ttcctaaaaa accaagtaac gatgcttttc catgttcaaa aaaaggagtc
     8161 actttcgtta aaaacagtgg aattatcgct aaaataacgg cggcaaaaaa ccatcctgtc
     8221 tgatttttcc tttgccgata aacaaaatag ccccatacaa gtatcgtctg ccacaaaaca
     8281 tacccaatca gcgccgctcc ctgttgccaa taattacctc caaagctgac aaataaaaag
     8341 aaaagtgtca ctgctgattg ataaactggt aatctttttt cccatatcaa taaagataga
     8401 acgatcggta caagcgcaat ggctaaaaga aaaaaataaa acggctctgc ataagggatc
     8461 atatgaggta acatcattca ggattcacct cagctgttaa tttttttcga tcgatttttc
     8521 cattaactgt ctgaggcagc agatcgacat aatggaactt ctgaggaatc atataatcca
     8581 ttacaacttc tagtaattgt tctttgatag atttagtcaa ctgaaaatcc ggctgtttcg
     8641 ttttgttttc taatacgaca aaagcaacca gctgctgtac ttttgttcct tggtattttg
     8701 gtacgacgac agcttgtttg attcggttgt cttggagcag ataatgttcg atatccccga
     8761 gttcaatccg gtatccatgt aatttgacct gctgatccat acgtccttca taaaataaaa
     8821 gcccatattc atctagtcta cctgcatccc ctgtatggta acttgctaag tcattttgac
     8881 aaaagaacgc agcagctgtc ttttcgggat tgttcaggta accttttgat acgcttggtc
     8941 ctgcaataat gatttcaccc gtttctcctt ttgaaacagg tttaccttct tggacaatag
     9001 aaactttcgt gtcttttttt acgtagccaa tcggtagtcg gtcataacta tctagtacat
     9061 gctggtcaat ctgaatactt gaaatagcta cagttgcttc tgttggaccg taagtattat
     9121 atatccgtgc atttgggaat cgatcaagta gactttctgc agtttttttc gtcaattctt
     9181 ctccgcaaaa taaaaacatg tccaattccg gcacattttc tccattgaat gtaggttcca
     9241 tcaagcaaat atccataaat gatggagtag aaacccacac attcaacttc aaggctggca
     9301 atgtcgcgaa taattgacga aagtcttgaa caactgcttt atttaacggc ttcagcattc
     9361 cgccagaaac taatgcagga taaatagaaa ataccgataa atcaaaagaa aatggcgctt
     9421 gggctaagaa atgcatacca ggcttgatcc caaagtcttc catcgtccat tgaacaaagc
     9481 tgactagatt atcatgactg atttgtacgc cttttggttc tccagtagta ccagaagtaa
     9541 aaataatata aaaattttct gtacctttta cgctatttct gggataaaat cctactggta
     9601 tcttcttgat ttcttgaaat tctttttttg ttatgacagg aaccgaagga atatcttcta
     9661 tccagtcccc gatactgatg accatagatg gtttagccac ccgaaagatc gataggatac
     9721 gctccttggg tgtatgctct tcaatcggca aataggcatg gccagatttg acaaccccta
     9781 gaaatgagac aatcatttca aactccaaat tgccaaaaac gacaattggt ccatcgcctt
     9841 ctaccttttt ttctaaataa taagcaagtg cgtctgatgc ttgtttcaat tcaccaaaag
     9901 tatgcgtctc atccgcctga taagcaactc gatcaggttc atttattccc caatcatcga
     9961 ttgcttcaat aatcgttttg atttccatac tcttcctcct aaaattcgtt atagataaaa
    10021 gttcctcctt gaatattttt atagtgatac agataaatca ggaacagcag tactgcacta
    10081 taaaaaattg ttcgaatgat gaattttccc caataattca attttggatt agaacgccat
    10141 ttgttcattg gattccctcc tcatataacc tcacacaaag tgtaactaat tttgacaaaa
    10201 agaaacatgt gtctagctta cagaaaccgt ttttttacta acagttttgt cacatagctt
    10261 ttataaaaat agcacatcaa atcactgctt ttttctttat aatttctcgt acttttaaaa
    10321 aatataaaaa ataaagaggt tgtgacaaaa atcgtgtcac aacctcttat tccaaataaa
    10381 tggtattcaa aatttagttc tatttattat cttgtcttat tccgtatatc attcctcgat
    10441 aatccgacaa tataactgac tcgtaatgac ataaagcaaa agatagataa ggatcaataa
    10501 gccactcaca agataagcca accagtaatc ggcagttttt atatactgag tgaagacatt
    10561 gattgcaaat actgcgtgag tgatccctaa tatcatgggt ggaaagaagg taagtgcgtt
    10621 ttgctcgaag atcatccgtc tgatccttct ttgtggaatc cccagcttag tcaataggtg
    10681 ataattttct ttttcttcct ctgcttctgc taattgccgg actgtcaaaa tactaccagt
    10741 agcaataatc acgatcatcc cgacaaatag tgtgacaaaa atattgatac cgattcgccg
    10801 attaactgca cgcaatttcg aatagctgga agagaaattc aaacgagagc tttcttggct
    10861 aaattgtgct tccttcattt ggtcatccgg aagtttcttt gtgctaattt ctccttgtag
    10921 acttccattt acgatatcat aagaataata aacagcattg agccacttta tcgacaggtc
    10981 attgctcagt cgttcatcta ttttttcatt atttccacct gatacatcta cattgactac
    11041 ttgataatcc acaccttttg ctttttcaaa aacggtatca tctacaatca gtacaggact
    11101 tagatatacc attgtttcgt cacctaatac acttggaagc atttgttgaa tcttcaattc
    11161 ttgattatct ggcagtccaa tactagatcc atataatgaa atattccgaa aaagagtttg
    11221 catttgatca agcaaaacag tatgaccagg tgatttcaaa gaaatgttcg gcaaatctgg
    11281 attaactttt ctgaaggctt gatattgtgt ttccgtgatc agattagcag tttgaaacat
    11341 aggttcttcg agattttgac tatagatact cccaatgact ttataatgca aggtgatttc
    11401 tttagttatc ttctgccctt cctctgctag aatcggcttg atttttttct ctgtctcaac
    11461 atcaaactga tagtccatcg gggaggaaac tttctcctgg taggataaaa tagtagagat
    11521 actagccgtg ccgccaattg tcattaaaga aattccgaga atgactgtaa tcagagaatt
    11581 tgtacgccaa cttttgagca aatgaacttg cgtgttaccc attatcaaaa aattgatacc
    11641 atagtaataa atcttccatt tactcaatat gatcaaaaat aaccgaaatg tataacagaa
    11701 aaacaaataa gtaccgacca cacaaacgaa aaaaattaaa aaaggaaaaa agaaaactaa
    11761 tgtatcaaga taatgataac tgatcatcca tgaagtgatt tccctaaaat gactagctcc
    11821 aaaatatccg ctcgttaaaa gtagtaaccc gatgactgcg agtaatcggt gccttgtcct
    11881 gaagcgcatt gttgaactat ctgcttgttc tttttctcca aaacttcgaa tcattggata
    11941 gcgccatatt ttccatattg aatatacaga tactgctaaa aggatgatga aaaaagcaaa
    12001 taaagtatct actactgatg gaatggagat aaaaaatgga ctagtaagat ccatatccat
    12061 cattcgaacc aaaatcattg aaaagagttt ggaaaaaata ataccgagta atatcccaga
    12121 aatacaggcg aacaatccaa ttatcatgat ttctaacaca tatatacctg atatctgcag
    12181 tttattcata ccaaaaagct gatagatgcc tatttccttt tgccttctat tcaagaaaaa
    12241 tcggttggca ctgaatacga aaaaaagcaa aacaacagta atgataaatc caccaaaact
    12301 caatccacca tctatcgaag tatcttgact tgctcttctg actaaagatt gatcgtaggt
    12361 cattgcgctg aaggaataat agatcattac ggataaagtc aaactgaaaa aataaacaag
    12421 atagcctcgt gactgccgaa aaaaactttt aacggctagt ttatacagca ttcatttttc
    12481 ctcctccgcc aatcgtcgcc tgcatgtcta ttactttctc aaagaactct cttcttgtcc
    12541 ctcttctgac aacttcagaa aaaatcacac catctttaat aaataaaatt ctatcgcagt
    12601 agcttgctgt atatggatca tgggtgacta acagtatcgt tgctttttct ttttgattca
    12661 tggtcttcaa gtagttcaac aattctgtag ccgacttcga gtccaaagag ccagttggtt
    12721 catctgcaaa aatcacttgt ggctgaacaa caagtgctct agcagctgca attcgttgtc
    12781 tctgtccgac agaaagttca tcgggatacc gtttgagcag ttcttctata ttcaacaatt
    12841 gagctacatg tcttactctc ttttccattt cctctttagt catccgttca actgctaggg
    12901 gcaataggat attgtctttt gcatttaggg tatcgatcaa attgaactct tgaaaaatga
    12961 atcctagttt ttttcgacga aagtcactga gctcactgtt tttcattttt gtgatttctt
    13021 ttccttggat cgagacactg cccatcgtag gcaaattgat cgtggacaag atattcatca
    13081 gcgttgtctt tcctgcacca cttgggccca taatcccaac aaactcgcct tcttctactg
    13141 tgaatgagat attatctaag gctttgacgg gagaaagttt gctgccgtag cttttactta
    13201 gatgtttcac ttcgatcatc ttttccaatt cttctcctcc tctttcattt ttcatttcta
    13261 tttatttgca tagtagcata tctacgaata atttgctctt atgtttttgt cacttttact
    13321 tggactgaat aaaaaatttt attcaattat tttattcagc aaaattaaat atgcaaaaaa
    13381 caaatccacc agctacaagt tttcaccttt tttcacaata aaatatacac tacatatagt
    13441 atagaaatcc aattatacag cacattgaat actatatata gccgatattt agttgctcct
    13501 tccccgattt tgttttatga tagacaagaa caatttagca ggagttgaag ataatgaaag
    13561 taaattatga agaaaaaact gtcgttactc agcagccaga gacatcccag atgaaagtca
    13621 tcaaacgcga tggccgccat gttgatttcg atgaacaaaa gatcaatgaa gcactgatca
    13681 aagcagaaaa gaaaattcac ggctcattat caccacttac ttatgaaaaa attcaaatga
    13741 ttgcagactt ggttgtccaa gaaatcaaaa gccggtttgc tgaaaatgtc aaaatctatg
    13801 agattcaaaa catcgtggaa catatattac tagaaaaaaa cgaatatgaa ttagcagaag
    13861 agtacatcaa ttatcgtacc aaacgagatt ttgctcgcag taaagcaaca gatatcaact
    13921 tttcgattga aaagctaatc aacaaggacc aaactgtcgt gaacgaaaac gcaaataaag
    13981 acagtaatgt tttcaataca cagcgagatc tgacagccgg gatcgttgga aaatcaatcg
    14041 gactgaaaat gttgccacca catatagcaa atgcgcatca aaaaggcgat atccattacc
    14101 atgatttgga ttatcatcct tatacaccga tgacgaattg ctgcttgatt gatttcaaag
    14161 gcatgctgaa caatgggttc aaaatcggca atgccgaagt cgaatcgcca aaatctatcc
    14221 agaccgccac agcacaaatc tcacagatta ttgccaatgt agcgtcaagt caatatggtg
    14281 gctgttctgc cgaccgaaca gatgaattgc ttgctccttt tgcagaattg aactataaaa
    14341 aacatctaaa agacgcggaa gaatggatcg attcgccaga acgccaaaaa gaatatgcaa
    14401 aagcaaaaac caaaaaagat atcttcgatg ctatgcaaag tttggaatat gaaatcaata
    14461 ccttatttac ttcaaatgga caaactcctt tcacttcatt aggatttgga ctaggagaaa
    14521 actggtttga aagagaaatt caaaaagcaa ttttacagat tcgaatcaat ggattaggga
    14581 gtgaaaagcg gacagctatc ttccctaaac tgatcttcac tttgaaaaaa ggtgtgaact
    14641 taaaccctga agatcctaat tacgacatca aacaactagc attggaatgt gcaacgaaaa
    14701 gaatgtatcc tgatattctg aattacgata aaatcgttga attaactgga agtttcaaag
    14761 tacctatggg ctgtcgttca ttcttgcaag ggtggaaaga cgaaaatggt caagaagtaa
    14821 atgtcggacg aatgaattta ggtgttgtta cattgaattt gccaagaatc gcgatcgaat
    14881 caaaaggaga tcagaataaa ttctggcagt tactgtctga ccgcttagaa atcatgaaag
    14941 atgcgcttct ctatcgtgta gaacgttgta aagaagccat tccagcaaat gcgccaattt
    15001 tatatatgta tggtgctttc gggaaacgtc tttcacgtac cgattctgtc aatgaattat
    15061 tcaaaaaccg tcgagctact gtatcgttag gctacattgg attgtatgaa gttgcttcag
    15121 ctttcttcgg tggcgaatgg gaaacaaacc cagaagcaaa agctttcaca cttgatatcg
    15181 tcaaagaatt aaaagctaat gcagatgcat ggggggatga atatggttat catttcagtg
    15241 tctattcaac tccaagtgaa agtctaactg accgtttctg ccgtttggat acagaaaaat
    15301 tcggcatcat cgaaaatatc acagataaag aatattatac aaacagtttc cactatgatg
    15361 tgcgtaaaaa cccaacgcca tttgaaaaat tggaatttga gaaggattat ccaaaatatt
    15421 gttcaggtgg attcatccac tactgtgaat accctatgct ccaacaaaat ccgaaagctt
    15481 tagaagctgt atgggatttt gcatatgaca aaatcgggta tcttggtacg aatacgccaa
    15541 tcgatcattg ctatcaatgt ggtttcgaag gtgatttcaa accgacagaa cgagggttcg
    15601 aatgtccaga atgtggaaat catgatccaa aaacatgtga tgtagtcaaa cgtacttgtg
    15661 gctatttagg aaatccgcaa gctcgtccga tggtacatgg ccgccataaa gaaatttcct
    15721 cacgtgtgaa acacatgaaa tgaggttgtg aaaaagctgt cctgcatcaa gtaataagaa
    15781 tagctaaaca aaaatagttc ctcatatttt tcgtttagtt gggcttatta ctgcagatgc
    15841 aagcttttga acaccgttta ttcagaataa gaggctatga caagtctttt ttcaccaccc
    15901 tctttcgatg gctttgtatc tttgaacgcc ctctatcaaa ataagaacaa gctttcttga
    15961 acaatggatt taggtcagtt tgttcttatt tatgtggtcg agtagatttt atcttcaata
    16021 gctatatctt tgaaccttaa atgaaagaag tttttttatg agaaatccaa aaccaaaaga
    16081 atggttagca aaagactaca gccaaaacta tattgctgac tacaaaccgt ttaattttgt
    16141 cgatggtgaa ggtgtccgca acagtcttta cgttagtggc tgcttatttg cctgcgaagg
    16201 ctgcttcaac aaagctgcac aaaattttcg atatggcaaa ccattcacac ctgaattaga
    16261 agaacaaatc atcgctgact tgcgcaacga ttacgtgcaa ggattaactt tacttggtgg
    16321 cgaacctttt ttgaatacag atgtttgtct gcaagtcgta cgacgtatcc gaaaagagtt
    16381 cggtacgaca aaagatatct ggtcatggac aggctatacc tttgatgaat tgctacaaga
    16441 ttcagaagat aaattagaac tcctttcgca aatcgatatc cttgttgacg gacgctttga
    16501 attaagcaaa cgtgacctaa aactacaatt tcgcggaagt agcaaccagc ggatcattga
    16561 cgtccaaaaa tctttagaat ccaatcaagt tgtgatttgg gaaaaatgta cggatgcaac
    16621 agaaacctat gaacaaatca aaaagcaaga cttgatataa aaacagcttt gggagagaaa
    16681 acggatttcc ggtttcaact ctcaaagctg tttttatatt tcttgatttt cccataatgg
    16741 aaggacgatg ttttcataag tcatcgggtc cagattcgtc aaagtaatcc ctaacaatcg
    16801 gattcctttt tctactccca agatttcctc ccatataagg cttgcttgat aaaagagtgc
    16861 ttctttttta tagatatatt ctggcaatgt cactcttttg gtcacagtag aatagtccgt
    16921 gtacctgacc ttcaaaacta ctgttttccc atgtttttgg actcttctca gtgcttcttc
    16981 tactttttca gctagttggc gcaactgagt cagcactgct tcttccgttt gcaacggctg
    17041 cccataagta tgctcttttc ccacagattt tcgctctctt gtaacgttta ctggagaatc
    17101 atggattcct ctgactttac gataaagaga atagcccatt tttccaaaat ttcgaatcaa
    17161 catcatttct gtgcattcat ataggtcttt tcctgtataa atccctagct catgcattct
    17221 aggtacagtt ttcttcccta ccccatgaaa tttttcaatt ggcaaagctt ttaaaaatgg
    17281 cacagcgtct tgaggggcaa ctaccgtgat tcctctaggt ttttgatagt ctgatgctaa
    17341 tttggccaaa aacttattgt aacttactcc cgcagaacat gttagctgga cactctccca
    17401 aatatctgct tggatcattc gggcgatttt gatggctgac ttgcaattga ttttattttc
    17461 ggtcacatca agatacgctt catcgatact aactggttcc acaatatctg tataacgata
    17521 gaatacttcc cgtacttgtt tggaaatatc gctgtattta tgatagtcgc caggcttaaa
    17581 gatggcttgc ggacaaagct catacgcttt ttgtgcactc attgctgaat gaattccgaa
    17641 ttttcttgct tcataatttg ctgtagtcac tactccacgc ccaccagtgt cactggggtg
    17701 tctggcaatt actaatggat gtccgcgaaa ctcaggatga tctcgttctt caaccgaagc
    17761 gaaaaaagca tccatatcaa tatgaatgat ttttcttgat gtatcattat gtaaaggaaa
    17821 ttgcagctcc atcatcctca cctcttattc atcatacaag aacattcgtt cgcgttcaag
    17881 agatttgaaa agttagtagc tgatttcctc attagtcttt cattatagac aacttatact
    17941 atctcagtct aattcatggt actgacggta gacttcttgt tttttcagcc catttttcag
    18001 cgctactgct ttgatagcag catttggttt ttcgcctgaa gcgatctttg cttctacttg
    18061 ttcctttaac gttcccaact cttcatcaac ttccgtcact ggcatttcga acaaattccc
    18121 ttctacaagc agacaacatt caccctttac tggatgttct tcgatataag cgagtagctc
    18181 ttccgtactt cctctaaggt attcttcatg gacctttgtc aattcccgac acaaaacgac
    18241 ttggcgattt ccaaaaattt ctaagaaatt cgtcaatgta gcagtgatcc gataaggtga
    18301 ctcataaaaa atcagcgtaa ctgtctgttc ttttagcttt ttcaatgttt ctttctgttc
    18361 ttttttctta cgtggaagga agccataaaa taaaaatggt tgaggcacta gccctgaagc
    18421 aatcaaagcc gtcatcccag ctgtaggtcc tgggatagag atcacagaaa tcccttcttt
    18481 tatgcaggct aaaactagct catgtccagg atcgctgatg gaaggcattc ctgcgtcact
    18541 gacttgagca atcgtttttc cttcttttaa caaagcaatc aattgaggga cacgttcttt
    18601 ataattatgt tcatgtaaac ttttttgggg tgtatggatt tcaaaatgat tcaataactt
    18661 ttgtgtatta cgcgtatcct cacttgcgat aagatcggat tcttgcagca tacgaacact
    18721 tctgtagctc atatcttcta aatttccaat tggcgtcggt acaagatata aatccccata
    18781 taccggattt cccttgaaac ttttttgatt atacatctgt cacaatctcc ttaataaaaa
    18841 gactggagca gtatttctcc gctccagtct cctcttgtta ttggtcatcg accgctttcg
    18901 cgatagatca cttctagaca aaacgcacaa ggctcgtcat tgtcccttct tgatccatat
    18961 aaatcgtagc agacatggaa tccttcttca taaatttttt caagattcat acgagactta
    19021 gaaagttcct gcttcacatt ttcagctgga gcttgtgcaa cttggttcaa ttcccgcagg
    19081 tgttcccgca gacgttgatt ttccatctcc aaagttgtat ttttttctac gatctcatgc
    19141 aaagcatgct tcatttcaac aagttctgtt aatgtatttc tcaactctga ttctaattga
    19201 ttcaatccgt cgtataatga tctcttatcc attcatctca cctacttgga taaattcttt
    19261 caattcatcc cattcatatt cgacaggatt ttcccgtcca gtcagccgaa tactaacgat
    19321 acggctaagc agattcaacc ctacgacttt ccctttacca tcaggtgtag caattacttt
    19381 tccaaagtca gggagttctt ttttcgctgt ctcgtattct tcgctctcat attgcagaca
    19441 gcacatcaag cgtccgcata aaccggaaat ttttgttgga ttcaaagata aactttgatc
    19501 ttttgccatt ttgattgata caggcacgaa atcgcctaaa aaagaagaac agcataatgg
    19561 acgcccacat ggaccaattc cgcctattat ctttgcttca tcgcggacac caatttgtcg
    19621 aagctcaata cgagtacgaa atacagcggc cagatctttt accaattctc taaagtcaat
    19681 tcgcccgtcc gctgtgaaag aaaaaatcaa tttatttcga tcaaatgtgt attcggcttt
    19741 gaccattttc atttccaact cacgcaactg cactttttct tttgcgattt tcaatgcatc
    19801 ataagcatct tttttgtttt ttttgtcttt ttctaattca gcttgtgacg ctttatgcaa
    19861 gatcggacgg atagcttcag gaaggtcatt gggatcaatc tcttttttag gaaggacaac
    19921 agtagcaata tgtaaggatt gctgagattc gactaatacc ttgtcactat aaacatattc
    19981 agagtctcct ggtgcaaaat aatagatatg acctgcatct ctatatcgga cacctactac
    20041 ttctaccatt tccatcctcc ttgatcatca tcctttgcgg caagctaaaa aatcgtatgc
    20101 aaaacgaact gttccgcaac agcctgaaaa ctgacattgc tgcgtagttt ctgctctgcg
    20161 atcaatatcc gttcaattat ctggtttatc tgtttcactt tgccatattc gccgtttgct
    20221 actgcttgac gctgtgcttc ctgataataa aacatcaaga cagataatcc tgtaaactgt
    20281 tgtgtttttt ctttaaatga ttttaccaat tttttttgga catagataaa ggcttgagta
    20341 tcttgctttt gcaagtaaac gaaccattga taaatcaagt ccttagcatc attaaaccat
    20401 tcatcttgag agatttcaac tgcttttcct aaactgtttg ttaagaaagc caaaagtttt
    20461 gctttttcca atggaatctg ctcttcttgc aatcgatgga tcagtgcttc tttcgaaagt
    20521 tcttgaaaat gcagaacttg acaacgagat tgaatagtag ggagaattct tcctactgca
    20581 tctgtttcta acaccgctaa aaaatctcca gggggctctt ccaagaattt caacaaactg
    20641 tttgccgcac tgctattcat tttttcagct tctttgatca aaaaaacttt ttttcttgat
    20701 tcgtaaccgc tgcgactgaa ttccgtctgc aaacgtctga tctgatcgac tttgatggtt
    20761 tgtccttccg gttcaataac caaaacatct ggatgttctt tcttttcgat ccgctgacaa
    20821 ttgttgcatt ttccacaagg cagattgtct ttcatttggg tacagaacag gtgctgtgca
    20881 agccatatac ctacttcatg ttttcctgtt cctttctccc cttcaaaaag ataagcatga
    20941 gcgatacgcc catgctcaaa actccgttga agctgctgat acacgatcgg ttgcatttga
    21001 gccaagttta tttcttgatt catagctcag ctcctcctaa aattgatgga atccttcaac
    21061 aggtaagacg aagactgtgg caccgcctac ttctacttct actggataag ggacgccccc
    21121 atccatcgaa atatccagtg taacaggtgt agatacaaat tgctttcttg attcacacgt
    21181 ttttttgatg atttccaatg cttcttctac acggtcatct tcaataccca cgataaacgt
    21241 actgtttcca gccttaagga agccgcctgt cgatgatagt tttgtggcac ggatatttgc
    21301 atcaatcaat tcatttgata aacggttgct gtctttgtct tggataatcg ctaaaataat
    21361 tttcataaac gttcaccttc ctagttttca aaaaattgcg gatactgttc aataattgta
    21421 tgataacttg tttgcagcac ttcttcaaag ctttttcttg catcaacttt gtggattctt
    21481 tccggattct cttctgccag ctttaagtaa gcatgacgta cacgctggtg gaattccaaa
    21541 ccttccgaat ctaaacggtc gatttgattt tgtctgtttt tcttgattct tcttaatccg
    21601 gtgtctgaat ctacgtcaag ataaagggta aaatccggcg tagtaccttc tgtagcaaac
    21661 tcattcaacc gagcaatctc ggtaacgccg atgcgtcggc ctgcaccttg ataagcaaga
    21721 gaactgtcga caaatctatc gcataaaacg attttccctt ttgccagagc aggcagaacc
    21781 ttttcgacta gatgttgtct tcttgctgct gcataaagca gtgcttccgt acgttcatcc
    21841 atccgatcat tttttggatc aaggatcact gctcggatct cttcagcaat cggaatgcct
    21901 cctggttctc ttgtttgaat gatttctgtt tttgctactt ctttcaaaag agggtaaagt
    21961 tcattcaaga tgctggtttt tcctgcacca tcaggcccct cgattgtaat aaatagtccg
    22021 ttcacattgt tgcccccatc tcttgtgctg cttttatatt gtatctgaaa aaacacttaa
    22081 ttagaaattt ataactcacg tcttccttcg acagctttca ataaagtaac ttcatctgca
    22141 tactcgatat cagagcctac agacagacca tgtgctagac gagtcacttt gatacctgcg
    22201 ggtttgatca gacgtgagag atacatagct gttgcttctc cctctgttgt tgcatttgtt
    22261 gcgataatca cttcttttac atctgcatca tgcagccgct gcaacagaga agaaatattg
    22321 atgtcttctg gacctgtccc ttccatcggt gataacacac catggagaac atgataaagt
    22381 ccgtgatatt ctcgcatttt ttccattgcc attacatctt tcggctcttc gaccactagg
    22441 ataacgcttc gatcacgtga aggatttcta catatttcgc agggatcttc ttctgtgatg
    22501 tttccgcaga tactacaaaa atgcaaatcg cgttttacac ttaacaaaga tttagcaaat
    22561 tcatttacta cttcatcttt catatcgatc gtataaaagg cgagtcttgt cgctgttttc
    22621 tgaccgattc ctggaagttt catgtagctg tcgatcagtt tcgcaattgg ttctggatat
    22681 tgcatattca ttactccttc agtttaaaac taaaatcctg gcaaaccttt tgcgtatttc
    22741 cctaattttt tctcagtttc cacatcaatt tgtgcgatcg catcattgac tgccattacg
    22801 acaagatcct gaagcatctc gatatcatca ggatcaacga cttcttcatt gatttggata
    22861 tctttcatgc gacgatcgcc tgtaaaaacc gctttgacca attcattggt ggctttacct
    22921 gtaaactctg ttttatttag cagctcttgt gcttctgcca tttctttttg cattttttgt
    22981 acttgtttca tcatgccttg catattgccc attccacgca tcataattat ctactccttt
    23041 ttattaatca tctaccactg taacagcttc ggagccaaac agttcctctg cttttactac
    23101 aagtgtttct tctggtactt cttgttcttg aggaagcaac tcgatttctc cttctgagtc
    23161 ttcagaagca aaagagtttt ctgttccctc ttcttgtgcc tgcgtcaaat aatttcttcg
    23221 aagttctggc cagctttctc ttgtaatata aacaggatca ggcgcataat ctttgatcat
    23281 tcggcttaag ttgttgtgta ccgaaagctg caattcttcg tcatttgctg ctctttgaca
    23341 aacaatctca taatcaaacg caatcactag tcctgtaggt ccagctgcaa ctggttcgct
    23401 tgctttaagc attgctcgct gagtgacaga tagactcatc agcaagtctt cccatacttc
    23461 ttttacttgg ttcagatgct gtcttgtcgc ttcccgcaga actttatata ctcgttccgt
    23521 cggtacacga taggtacttg tctgtttttt atgatttgtt tgctgtaccg gctgtacttt
    23581 tgtattctca attcctgtat tactgcgtag ttccttgatt tcgtttctta gttccttaat
    23641 ctcttgttgt agctgtttta ctatctgatc atctgcaaat gctacatctg ctgaaggaac
    23701 agaagcagac ggtagctgtg caagtttgac tgtagcgact tccaaataaa tagcggcact
    23761 attggtaaaa cgaatttcat tttgagtatc gctcaaaatc tttatcattg aaaacagctg
    23821 atccgctgaa acagtttgtg ccaattctgt aaatgtactt ctgatcgtac tcgattgttc
    23881 ctcaactagg ttaggtgctt gctgatacat cagcaagtca cggcagtatt gtaacatatc
    23941 ctctagaaag cgacgtgatt ctttgccggc tgcgagaatt tggttcaatg tttccaatgc
    24001 ttctggtact tcttttttca cgcaagcact caagtaactg tccatcattt cgtcagttaa
    24061 gctacctgtc acttgcatgg catcatctaa agtaattgtt ccttcactaa acgagattgc
    24121 ctgatcaaga atactcaatg catcccgcat cccgccttct gcagaacggg caatcacatt
    24181 caatgcagct ggttcatagc tgatagtcga ttctttcaag ataaattcaa gatgttcgac
    24241 aatatctgcc gtattgatcc gtttaaaatc aaatcgctga gtccgtgaaa tgatcgtagc
    24301 tggtattttg tgaggttcgg tcgttgctaa gatgaatatg acactttctt ttggctcttc
    24361 caatgttttc aacaaggcat tgaaagctcc tgttgaaagc atatgtacct catcaataat
    24421 gtacactttg tacgctgcct ttgtaggcgc ataatttgcc cgatcacgga taaatcggat
    24481 ttcttcgact ccgttattgc tggcagcatc gatttcgatc acatcttctt gcgtaccagc
    24541 agtaattgat cgacacattt cgcattcgtt gcatggctca ccgtctttac tgttcggaca
    24601 gttgattgct tttgcgaaaa tctttgctgc actcgtcttt ccggttcctc tgggtcctgt
    24661 aaacaagtag gcatgtgagg ttttgtggga aacaatagca ttttttagtg tctgtgtcac
    24721 agctttttgt ccaacgatgt cttcgaaacg ctgcgaacgc cagactcgat aaagtgcttg
    24781 atatgccata aggatccccc ttttttaaaa aattcactat ctcttattat acgtgatatt
    24841 aggtaaaaaa actactatcc ttctcggctt tttcaggtat ttaaacaata cgcaattttc
    24901 catttcaatt ccgtctctag tccgagaagt ttcacatctt cctatggtat aataaataaa
    24961 caataattgt ttggcactag ctgaatcaga ggaggaattt tttatgggtc ttatcaaagc
    25021 agcaacaagt atggttggcg gcggtctggc agatcaatgg ctagaagtca tcgaaccaga
    25081 caatatgagt gatacaacgg tcatgacaaa aggtgtcaaa gtccgcaaag atgacaaacg
    25141 tggctccaat cgtaaaggaa cagaagatgt tttaacagac ggaacagtcg tccatgtcta
    25201 tccaaacatg atgatgcttt tggtcgatgg tggaaaaatc atcgattata ccgctgagga
    25261 aggttattac accattaaaa atgacgcagc tccttccatg ttcaatggaa cactgaaaga
    25321 agcaattgct gaaacttttg accgattcaa atttggcggc gtcacaccgc agaaacaaca
    25381 agttttttat atcaatctcc aagaaataaa gggaatcaaa ttcggtacaa gcgcgccgtt
    25441 gaactacttt gacaatttct ataacgcaga attattctta cgggcacatg gcacttattc
    25501 tattcatgtc gttgacccga ttttatttta tacaaacgca atccctaaaa acaaaacaca
    25561 agtggaaatc aatgatatca atgagcagta tttagctgaa ttcctaacag cgctacaatc
    25621 agcaatcaat cagatgtctg cagatggtca acggatttct tatgtaccat ctaagagttt
    25681 ggaattaagc aaatacatgg atactgcatt ggatgattct tggcgtgaat tacgtgggat
    25741 ggagattgtt tctgtggctg tagccagcat ttcttacacc gatgattctg tgaaactgat
    25801 caatatgcgt aacgaagggg cgatgctagg tgatcctagc gtacgtgaag gctacgtgca
    25861 aggttccatt gcacgtggta tggaagcagc cggaaaaaat gaagcaggag caatgaccgg
    25921 ctttatgggt gtaggtatgg gaatgaatgc aaatggttct tatctttctc aagcagctca
    25981 aaataaccaa gaacaaatca aacaacaagc agaaaaacaa aatcaacaaa ctgcacaagg
    26041 aaatgcggat acttggacat gtccagtttg cgggacagaa aattccggaa aattctgttc
    26101 caactgcgga gctgccaaac ctgtagaaaa cgttcagcct aagctacaaa tgcgatgcag
    26161 tgaatgcaat gagatcgtgg atctttccaa cggcatccct aaattctgtc caaactgtgg
    26221 taaaccgttt aaaggaatcc ccgttaatta atttatttag aaaggtgtgc agctgatgga
    26281 tgttcttaca cataaatgtc ctaattgcgg cggtccgttg acttttgatc ccaaagacca
    26341 aaaatttcat tgcgaatact gcctgaatat ctatacagaa gaagaagtca gccaatatga
    26401 gcaaaagcaa aaagaagcgc gtatggctgg cgaagaaagc aaagaagaac cttcacctac
    26461 cgaagatttt acttttacag cccaagaaca gcttgccgat atgaatgaag ccgagcgcaa
    26521 agcggttgac gaggcaggcg gtttttcaga tacagcggac gaatctgcag ataataccgc
    26581 agcgatagat ctttttcttt gtcccaactg tggtgcagag atcgtgactg atgcgacaac
    26641 tgctgcgact tattgttact actgccataa tcccgtcgta ctatcgggac gtttaagcgg
    26701 agaattcttg ccaaataaag tacttccttt tgctgtcgag aaagaagaag caatcaacag
    26761 atttctcgct tggaccaaga aaaaatggtt tgttcccaaa gcttttttca ataaggatca
    26821 aatcgataag ttgacaggtg tgtatttccc ttattgggct acagatgctg aagtagatgg
    26881 tgccatgcag gcgaatggta cagttatccg catatggcgg ataggtgaca tcgaatacac
    26941 agaaacgaag caatttgctg tttcaagagc aggcaagctt tcttttaaag aactagtaaa
    27001 aaatgcctta tcaaaaaata cgcaacaaaa gatggtcgaa ggcgtgcaac ctttcccgtt
    27061 agataaagca attgatttta aaagccagta tttagccggg ttccaagcag aaaaaagaga
    27121 tatcgaatat gaggcaatca aatcacagat tcaatctgaa ttaaaagact attcagagaa
    27181 gctgttaaaa gataccgcaa atggatatac aacattgacc ggtgtgcgaa cttctgcttc
    27241 aatcacaaac gaagtaaata attacgtatt actgccggta tggcttgtta cttatcgaag
    27301 caatgactca agtaaaaaag tctactacta cgcaatgaat ggacaaacag gaaaggtcag
    27361 cggtgtcctg ccgatcagcc agaaaaaatt gggactgacc gctcttggga ttttcgctgg
    27421 gctagcgatc ctctttctga tcggaggtta cttgatatga tgaaaaaatt ttttttattc
    27481 tttcttttgc tagtaagtgt tggctggccg gtggctactc atgcagatac agctacggta
    27541 aatgatgagg ctgggttatt cacaacagat caaatccaat ctttggaaca acaggcagaa
    27601 aagctgaatg aaaaaatcaa aggacgagtc ttgatcgtaa cgactacatc taattcagaa
    27661 gaaccaagag actttgctga taattactta agagacgcag tcggaaatga tcaaaatggc
    27721 tcagtattgc tattagatat gggacagcgt gaaatctaca tttcgacttc tggtaatatg
    27781 atcgattatt tgactgatag cagaatcgat tcgatcttag atgatgttta tgatcagatg
    27841 acaaatgctg cctattacaa tgctgcaaaa gcttacctgt ctaaatcagc aacatatgtg
    27901 gaagacggag ttccaggagg acattatcgt gtagacgaag aaactggcaa aattacacgc
    27961 tataaggttt tgacgacagt agaaatcatc attgctgttg ttttggctct tatccttagt
    28021 cttgtctttt attttgtgac tgtttcgcgt tatcaattga aatcaggcat ctacaaatat
    28081 ccattccgag aaaaatccag tatcaaatta actgaaaaaa ccgatcgtct gacaaattct
    28141 tttgtcacga caagaagaat ccccaaaagc ccacctcctg gaagcggcgg tggcggaagt
    28201 actacccatt ctagcggtgg cgggactttt ggcggtggcg gcagaagttt ctaaaaattg
    28261 ctaaatgaat gttcgcaaaa aaagggctgt gacaaaaatc gtgtcacagc cccttttgtt
    28321 gcaaataaac ggcgttcaaa agcttacatc tacggtgata agtccagcca agttaaaaac
    28381 ataagagact gtttttactt ggctcttctt attacttgat gcagaacagc tttttcacaa
    28441 cctcttggta aacggtgttc tcctaccaac tcctcggtca caagtcacaa tattcatcaa
    28501 acatgaaaag ctgttttttg aaattgttcc ttgtgactca gagttaaacg gcaggctcac
    28561 aacctcttgg taaacggtgt tcaatcagct gaccctcggt attagctcaa aaaacggcaa
    28621 aatatgagga actatttttc cgtttgtttc tctaatactc aggtcaaaac gctgatttca
    28681 caacctcttt gttcatcaaa agataatatt gtcttctaac aagtccatat tcaaaataac
    28741 gatatgatgg tctttaacgg tgataatacc atcttttttc agttgtttta aaattctgtt
    28801 tacactgcta gcagttgaga tgccacaaaa tttggcgatt tcttcattcg tgatcgaaaa
    28861 atcgatcagc atcccttctt ctgtccgcac accgaataaa tcatataatt cgtaaagttg
    28921 cgtacaaaca gctcccagct ttccgtttaa tagcatttgc tgcatttttt tcatcgaata
    28981 aagcagacga tagcggtaat actcttttac atagtgttgt agctttgggt cttggttgat
    29041 attttgccaa aagcgcacac gattgattcg ataaaactct gcatattctg attcaactcg
    29101 aatattatac ggcgaatcga tgaattgtga atattcgtct tttaaaagag agacgatttc
    29161 aagatctttg atatagcgaa ggttaaattc tctcccatca tttgaaataa cacttgcttt
    29221 taccgttccc tctttcaaga tatacgtatg ggaatcttcc atcccttcga atgtcaaata
    29281 tttatgatat cctttgcgta taatcggaaa atcattttta tccaaatatt cctttaagac
    29341 tctactatcc aatgatgctc ccccatccaa actttcatct aaaaagatca tacagtactt
    29401 taaaactttt taaagtccaa aggtatttta ctaatgatat taacatttgt taagtacctt
    29461 tttccatcac ttatgcgatt tttttccttt tttttattcg ttatactgca gaagtaaaat
    29521 tttttaagaa tagagggaaa aaacatgaat tactggatga acacaatcat taatcgatta
    29581 gaaacagcat atcaaacaag atttgatatg aaagcttctt tagtcttttt aaatgatgcg
    29641 tatcaaaact cgatcgaatt gatcaaagca gtggatgaga atccaacaaa cgaatgcgaa
    29701 gaatttttaa atctgtttat gtctacaaga gatttattta ttcgccaact tgttgatcgc
    29761 tatccatcca attatcacga tgtagaagtt caaatacaaa aattaaaagc atattcagct
    29821 taaggggaat gtataacata catggaaaag aaattattta ataaatattt tattggaatc
    29881 acattgatca attttattgt ctacctgatt tattatctgt tgatggtcat catggcagtc
    29941 attgcgcaag acaccttaca cgccagcttg agccaagcag gttttgcttc tgggatctat
    30001 atcatcggaa cattgctggc acgcttattc atggggaaac agttagaact atttggtcgg
    30061 aagtttacct taagaggcgg cgcgatcttc tatctccttt caacattagc atatctttat
    30121 acgccaacta tcggggcatt gtatttagtt cgattcttga atggattcgg ctacggtaca
    30181 gtttctacag ctacaaatgc tatcgttact gcatatatcc ctgcatctaa aaaaggggaa
    30241 ggcatcaatt attatggatt aagtactagt ttagctgccg ctgttgggcc atttttagga
    30301 atgattttgc tgaatatgac tgattttcgt ttcattatct ggttttcaat tgtactggtc
    30361 ttctttgtta cgattgcctg ccttgtcttt cctgtaaaaa atattccatt atctgaagaa
    30421 caaaaaatat ctcttcgctc atggaatatc aatagtttta ttgaaaagaa agcacttttc
    30481 attacaggaa ttgccttttt gatgggtctt tcttattcaa gtgttttatc atttttatct
    30541 tcttatacaa aagtaatcca cttagttgct gctgggtcat ttttcttcgt cgtatatgct
    30601 ttggtcatca catttacacg tccattgact ggaaggattt tcgatgtcaa aggagaacaa
    30661 tacgtgatgt atcctagcta tttattctta acagcaggat tatttttact gagtgtaacg
    30721 acgaatagtg tgacattgct tatctctgga gcattagtcg gcctaggtta tggtacgttt
    30781 atgtcaaatg gacaggctgt ttgtttaaaa atcgtccgcg aacatcgaat cagtattgct
    30841 ttatctacct actttattgg tttagaccta ggcttaggcg ttggtcctta tttgatgggg
    30901 atgctaaaat ctcttacttc atttagagga ttgtatgtga ttgccggagt cattccattg
    30961 atatgtacag cactctatct tgttaatggc cgaaaacata gtcatgaagc agagggcgaa
    31021 ttgattgaat cattgaaaaa tgaaatttga tcttgatgaa tagataaaaa aaaccgttca
    31081 gatctgaaaa taatctgagc ggttttttga gtaaaaatag tttatgatta ttcttaatta
    31141 aacatctatt tatttttaaa gctttcattt atcgataaga atagtttaac tgttgattta
    31201 ttccattttc cgttcatctg gtacgatgcc ttgacttagc aaccacttgt ggaagaacca
    31261 ttctgccaca ccgatcaata gagcaggaat caatactttc atccaaatat cgactgtatc
    31321 attcataaaa tatagataga gccacaagat aactgcagct gaaccagcat ctgcgatcgt
    31381 cgctgcgatg ttccctactt tacgtaagat caacagatcc cctagcacat agatcatgac
    31441 tacaataatt accccaacaa tcgttgaatc cataaagcta acaccgtata aacctgtcag
    31501 cacgacccac agaatcgccc agatcatgat tgccttcact accaacgcct tcacatgttt
    31561 cattttctgc actcctttct cctggataaa aaagtaagat tatctaacaa gataaccttt
    31621 tcattattat accatcggct gagagaagcg agcaaagata aggtcctatc taaaaatgag
    31681 gaagccactt agaacattca cgtaataatt tatccgtaca gacattcgat atggtgttcc
    31741 tttactttcg catactgttc ttttgtcagt tctttacttg tcaccagata atcgatttca
    31801 tgaaaagcaa tggcttgatg catgaattta tgtgcaattt tttgctgtgt aactaaaacg
    31861 gcaagccggt ctgattgttt tctaaaagct tttttgacca ttgcctctcc ttcatgagtt
    31921 tctgttactc cttggctgaa atctagcccg cgacaactca ttatcgctaa atccgcataa
    31981 tatgacaatg catcgttata ggcttttgaa ccgttgattg ttgctcgttt cggaacaatt
    32041 gcccctccca atacagatac ttttgccgtt gtatattcac tcaacatagc agctgtgacg
    32101 atgccattcg taatgatctg caaaccatca aatcttgcta ggtttctgac taagtgtaaa
    32161 gaggttgtac tggaatccaa gaataagacc atatcatctc gaatcaaaga agaagctgta
    32221 tctgcaatct tacgtttttc tgtttcttct tctaatttgg tgatcttcat caggtaaggc
    32281 acgtcaattt ttcgattgtc aataagcatg gcgccaccgc gaactctacg gatcaatcca
    32341 cttttttcca gaaaaacaag gtcacgttta atcgtggctt cgctataatt tactaactcg
    32401 atcaaatcgg tgactcttgc aaattggttg ttttttagat aattcacaat ctcctgctgt
    32461 ctattctcca cttcattcaa cataaaatca ccccatttac tttatatagt aacaggaaaa
    32521 aagaggttgt gacagaagtg attggcttcg agaaataaga agaaattttt cgaaaaaact
    32581 acttctgaac atcgtgtgtg gttaagaggg tatgacaaga ctattgtcat accctcttga
    32641 ccacacattt ttatttttag tataaactag ccttgcctac tgtgttcaaa atttccattt
    32701 tatgtttgac cacttcttgt acctttttat tagctgctgg ataaattgca ttcggctcgt
    32761 acatcgatgg attttcactc aatatttctc tcaaagcatt gaaaaagacg cttttaagat
    32821 ctgagctcaa attcactttg gcaactccgt attttactgc ttcgctgact tctgcgtccg
    32881 gattacctga accgccatgt aaaacaaatg gaagatcgat ttgttggttc aattctttca
    32941 gtaagtcgat atttaatttt ggagttctgt ttttcggata caagccatgc gctgttccaa
    33001 ttgctacagc aagtgtatcg attcctgttt ctttcacaaa aatcttcgct tgatcaggat
    33061 ctgtataaat gattgtttca gcacctcctt cagcagaacc attattccca atcgttccaa
    33121 gctcagcctc cactgagaca tttaccgcat gagctaacgc aaccactttt ttcgtaatct
    33181 gtacattgtc gtcgaatgat ttcaaagacg catcgatcat cacggaagaa tagccgtttc
    33241 gaatcgcccg taagacatct tctatcgtac cgccatgatc caagtggata acgatcggca
    33301 gtttacttgt ataagcatag gctcttactg ccgcaacaaa ctcatcactt aaataggcga
    33361 tttcatcagg atgaatttct aagattactg gtgcttctaa tctctctgct tcttcgatga
    33421 ttgctttcat catatcatag ctgcaaatat tgaaggctgg tactgcaaat tgattctctt
    33481 tagccacttt caataactct ttcattgtat ataacattac gcttccacct catttgttag
    33541 attttcattt ttcgtccact tgtcttgttt tttctctttc actgtttttt tcaatagtcc
    33601 aagcataaag gctgtagtga ctgtacctga tgcaattgcc aagacataca taggtaaatt
    33661 gttcataaca tttggaatta gcatcaccca aatccctcca tgaggtgcca ttgaagtaac
    33721 tcctactgcc atggaaatcc ctgcagcgac tgctgaacct gtcatcaaac taggtatcac
    33781 gcggatcggg tcagataccg caaacggtat agcaccttct gtaatatacg aagcgcctaa
    33841 aatccagcat gattgacctg aagtccgttc ttctttggta aatttatgtt tgaataataa
    33901 agtggctaaa gcaataccta ggggaggtgt cattcctgca gccatacaag cagcaatcgg
    33961 tgcatttact ccagctgaca tcaaaccgat cgagaaagtc gaagtcgatt tattgatcgg
    34021 cccacccata tcagctgcca tcatgatccc gataagtaat ccgaacaata gcccggatgt
    34081 atttcccaag ctattcagcc aatttgtcaa agcatccaac acccatgtga tcggttgttc
    34141 aatcacaaat accatcaaaa gcccaataat taagatcgat aaaaagggga cgacaatcag
    34201 ctgataaata gcagaaaatt ctttttttac gctaatttta tttgccagaa aatcacagat
    34261 ataccctgct agcacgccac caatcattcc gccaagaaaa cctgaaccac ctgtagaggc
    34321 cagtaatccg gcaacaattc ctggggcaaa acctgctttt ccagcaatcg atgtagcaat
    34381 ccccgcgcct aacgcaggaa ccatcatggc aaacgctgta tctcctccga tccttgaaaa
    34441 tgcagctgct aacacattat agtctgctga gttgggatca gccgctgtaa tcccaaaggc
    34501 aaaactcagt gcgatgatga ttccgcctgc gatcacaaat ggaagcatgt aattcacacc
    34561 attcatgaaa tgattataga ttgtcggctt tttctcattt gcagctggtt ctttttcatt
    34621 agacacaacg aatacgccaa tatctctcaa tgcttcgtct attactactt gcggttcttt
    34681 gattgctcgg cttgtagaga cacgctttac ttttttcccg gcaaatcggt ccaattcgat
    34741 ttctttatct actgcaagaa tgattgcatc tgcctctttg atttcttgtt cagataactg
    34801 attttctgtt tttacacctt gtgtttcgaa ttttgcttga tggtttagat ttcttgctgt
    34861 tacttctaat ttttctgccg acatataagt atgagcaatt ccagtcgggc aagcagttac
    34921 accaacgatt ttcatgatta ttttcctcct ttttcttcac tatcgatact cggacaaaga
    34981 ctctactatt ttcattcttg actaatctgt ctgatgatat ctgctggcgt agtggcttct
    35041 tttattccct ttctaaaatc tgcattcatc aatcgtctgg agagtgtgct gagaatctct
    35101 agatgcatat ctgctgattt ttcaggaact acgatggcaa aaatatattc aattggcatt
    35161 tcatctatcc cgctatagtc cgttaatttg gctgtatgaa aaaaacacag tgctggtttt
    35221 gtcacatatt tgctttttgc atggggaatc ccaaatccat cttctattcc tgtggagatc
    35281 tcctcctctc gtttgaatag tgccttaacg actttttgaa catttcttac cttatttgtt
    35341 tttttcaaca catcccctat tcgctcaaat aatgatcctt ttgaatctat cgatggatcg
    35401 aaaacaatca gttcttctgc gatcaattga tcaaacctca taaaaaacct ctcccccaca
    35461 aaaaatgtta acgttttctt ggaactgagg tcagtatagc atcgctagct gtaccgttca
    35521 atattatgaa tgaacagagg aaaaagaccc atcatccgcg tgtataagtc attaaaatga
    35581 acgatctagc tcacaaacaa tcgcaagtct ataacaaaac aaaaagcctt ccttgaaagg
    35641 aaagcttagc ttctaatttt aggtaaatgg ttttttactt cgaaataacc cctcttcatt
    35701 tcgttaatat aaggtgtttt tatcaagtgg ataattaaaa ctatatacta gtttttcatt
    35761 gttttgtgca ttatgatcct acgacttttt cagcatcaaa cgaagtttta aattggcaaa
    35821 aaacataaaa aaacagacta tccctatcag atagtctgct aaacgttgag ttatcagcgt
    35881 ttttattatt ccgcagcgtt tgcgtctttg agaccgtatt ttttgttgaa acggtccaca
    35941 cgtccgtctg cttgtgtgaa tttttgacgt ccagtgtaga atggatgtga gtcagaagtt
    36001 acttcgacac ggatgactgg gtatgtatta ccgtcttccc attcaactgt ttcttgtgaa
    36061 gtttttgttg aacctgacaa gaatttgaaa ccagttgttg aatccatgaa tactactggg
    36121 tggtaatctg gatggatgtt ttctttcatg attttttcgc tcctttgccc tgctccattt
    36181 gctgaaccag agttgatttg tcgatttaca acattaacat cttaacatgt ttcagtcaag
    36241 gttgcaatta tcttttcaga tttctggtcg gatttttttt accaaaggag acatcttgaa
    36301 attctttgaa aaattgctga ttgttttttg ttttacgcaa aaagcggatc agttgttccg
    36361 tatattctaa tgaatctcca gtcatatttt ttcgaagttt ccaaatttct tctaattctt
    36421 cacttggcat caataattct tcttttcggg tacctgattt tttgatatcg atggctggga
    36481 agatccgacg ttcagataat tcacgtgaaa gttgtaattc tagatttcca gttcctttga
    36541 attcttcata gatcacgtca tccatacggc ttcctgtatc gactaaagcg gtcgctaaaa
    36601 tcgtcaaact gccaccttct tcgatgtttc ttgctgcccc gaaaaatttc ttaggtttat
    36661 acaatgcggc tgggtcaatc ccgccactca atgtacgtcc gcttggtgga acgactaagt
    36721 tataggcccg agcaagtcta gtaatactat ccatcaagat aacgacatct cgtttatctt
    36781 cgactaaacg cattgcgcgt tccaatacta attcagaaac tcgagtatgg ttttgcggct
    36841 gcagatcaaa tgtagaagat accacgtcgc ctttcacgct tcgttctaga tccgttactt
    36901 cttccggtcg ttcatcaatc agtagaacga ttaattctac ttccggatag ttttcggtga
    36961 taccatttgc gatttctttt aatacagaag ttttccctgc ttttggcggt gcgacgatca
    37021 atccacgctg accaaaaccg attggagaaa agatatcgat cattcgggta gatagtcttt
    37081 gcggtgttgt ttccagttga agctgtcttt gcggataaag aggtgttaag gctggaaaat
    37141 gcggacgttc ttttgcttct tccggatctt ttccattaac gctttccacg tgcatcaaac
    37201 cataataacg ttccgattct ttaggtggac gggcttttcc tgccactttg tccccatttc
    37261 tcaaactgaa tcgtctgatt tgtgaggcag aaatatagat atcttctgca cttggtccat
    37321 aattgattgg ccgtaaaaaa ccgtaaccat cttgaccaac gatatccaat attccttcca
    37381 tataataaaa tccttgtttc tctgcttgtg cacgaatcac agctagagat aattcctttt
    37441 tattcatctt actgtaataa ggaattttaa attctttggc ataactataa acttctttta
    37501 acgttttgtt ctctagttct gccattgtca aataatcgct cattcagctc ccacttcctc
    37561 tatcatttca attgatgccc ctaaggctgt tagtttctcg ataatatgat cataaccgcg
    37621 taagatataa tctacattgt aaatcgtcgt tgtcccttct gccaatagtc cagcaatcac
    37681 taaacaagca cctgcccgaa gatcagaagc cacgacttct gtgccgtgaa gtttatttgg
    37741 accattcacg atgatcatat ttccttccac ggtaatatca gcgcccattc gtgctagttc
    37801 cggcacatgg ttcacacgtt tcgcatagat cgtatcgatg atttctgaag tgcctgtagt
    37861 catcaatagt aacgcagtaa gtggctgctg cagatctgtg gcaaatcctg gataaggata
    37921 ggtcatgatg tttgcgggtt ttaattcttt cgaggggtaa acttcgattt catcttcgct
    37981 gattttcata tggacaccaa tttcctgcaa ttttgctata aagctttcca aatgttcaaa
    38041 gatcacattt ttcactttga taccatttcc tactgcagct gctaatgcta gataggttcc
    38101 tgcttcgatg cggtcaggaa tcatgaaatg ccgacagcca tgtaatgttt cgactccttc
    38161 gatacggatc acatctgtac ccgctcctcg aacttttgcc cccatattat tcagtaaagt
    38221 tgccacatct atgatttccg gttctcgtgc agcgttttca attactgtct gtccttttgc
    38281 ttttacagca gctaacatca cattgatcgt tgctccgact gaaaccacgt ccatgaaaat
    38341 ccgattgcca cgcaatcctt tattttctgt ccgtaaatac atggcaccat gttcatttgt
    38401 cacttcagca cctagagctt caaatccttt gacgtgtagg tcaatcggtc tagggcctaa
    38461 ataacagcca cctggcaggc ctactaccgc ttcgccaaat ttaccaagca gtgttcccat
    38521 aaaataataa gaagcacgca aactattgat ttttccgtgc ggcatcggaa tcgatacgac
    38581 ttctcgagga tcgatttcta gtatgttgtt ggaaaaatgg acagttgcgc ccatgatctc
    38641 taaaatttca attaatgaat gaacatcttg tatgtccggc acaccttcca agatcactgg
    38701 ggaatcagct aagattgcag ctggaatcaa tgcgactgca ctattttttg caccgctgat
    38761 cgttacttca ccagctaaag gtcggtttcc tttgattacg atttttttca tctgtttcca
    38821 ccttgtttat taatcttttt tcatggatat gcttgtattt tatcatagat aaaaaaaaag
    38881 aaacaagcat ggtctgccgt tttaagtaaa aaagaatgga gagcgacttc aaaagtcgtt
    38941 ctccattcct atatatcgta tctgttatgt ggatgcttac gctttgttag ctgaaccgaa
    39001 ccagtcgata tgagatttag catcttcaac gattgctgct ttacctggag ctaataattt
    39061 acgagggtcg aatcctttac cttctttatc tttaccagct tcgatatatt tacgagtagc
    39121 tgcagcaaat gataattgga attcagtgtt aacatttact tttgagatac ccattgagat
    39181 agctttttcg atttgatctt gaggaatacc tgatccgcca tgtaatacta aaggcatgtc
    39241 tggacctaca gcatcagcaa ttgcttgtaa gtggtcaaaa gctaatcctt tccagttttc
    39301 tggatattga ccatggatgt taccgatacc gcaagctaag tagtcgatac ctgtagcaac
    39361 catttgtttg cattcttcaa tatcagctaa ttcgccgtta ccgatgattc cgtcttcttc
    39421 tccgccgatt gaaccaactt cacattcaac tgagatacct tttgcatgtg ctttttcaac
    39481 aacgtcttta gctaatttca agttttcttc aaatggtaga tgtgaaccat cgaacattac
    39541 tgaagtatag cctaattcga tacattccaa agcagcttcg taatcaccat ggtctaagtg
    39601 gatagcaact ggaacagtga tgttcattgc ttcaactaaa tcagtgatta aatctttaca
    39661 gattttgtaa ccacccatgt atttagctgc acccattgat gtttggataa gtactggtgc
    39721 ttgttttgct tcagccgctt caaggattgc ttgagtccat tccaagttgt ttgtgttgaa
    39781 tccgccgaca gcgtaaccgc ctttacgagc agcttttaaa aattcagctc ctgatactac
    39841 tggcataata aaattcctcc taagttttgt aaaactaaat ttgttaagac aattcttaac
    39901 caacgaccct attttaccaa acatttcggt agttttctac taaaatcaat gaaaatgaaa
    39961 attttcaaga agttttttgc aaaaaataaa atatccaata gcgctttaat cgaaaaaagt
    40021 cttttgcttt ctatcttttt tcctacaaat aataacaaat cagaaaaaga gaaaagtgac
    40081 aagaaaattg cttatcccct tctcttgcta cttttctctt tctatcaagt tcaaaaatta
    40141 ttttgtttcg tgatctgcta atgatgctcc gacaaatgct ttgattaatt tttgcgggcg
    40201 atttggacga gaaatcaatt ctgggtggaa ttggcatccc acaaagaatt ttttctctgg
    40261 cagctctacg atttctacta aacggttatc tggtgagaca cctgaaaaga ctagcccttg
    40321 ttcttcaaac aattgacgat atttgttatt gaactcatag cggtgacggt gacgttcttg
    40381 cacaacatcg gctccatcat atgcttcagc cgtcttcgtt ccttttttga ttttacatgg
    40441 gtataatcca aggcgtaaag ttccacccaa attctcgatg ttttcctgat cagccattaa
    40501 atcaataata ttgtttgctg tatctggatt cgtttcagct gatgacgcat cttctaatcc
    40561 aacgacgtta cgtgcaaatt cgacacaagc catctgcata ccaagacaaa tacctaaaaa
    40621 cggaacgtca ttttcgcgag cataacgaat cgcttcgatt ttcccttcta ctccgcgatc
    40681 accaaatcca ccaggaacca agattccatc tgcgtctttc aaacgttctt ctacattttc
    40741 tctcgttaat tcttgtgctt tgatccaatc gatctcgatg tctgaattat aggcgaaacc
    40801 agaatgtttc aatgcttcaa ctactgagat atatgcatct ggtaactcga catatttacc
    40861 gacaagcgca atccgtactt ttttcttcaa gttcaagaca cgttcttcta attctttcca
    40921 ttctgtcatg tctgcttctg gtgtatctag ttttaaatgg tcgcaaacaa tttgatccat
    40981 tccttgtgct tgtaaaacta atgggatgga gtaaagtgta tctacatctg gcgactcgat
    41041 aactgcttct ggttcgacat cacaaaattg tgccaatttg tttttcacgc tttgagaaac
    41101 aggttgctct gtacgtacca ccaaaatatt cggttggata cctaaaccac gtagctcttt
    41161 tacactgtgc tgcgttggtt tagttttcat ttctccagca gctttcaagt aaggaatcaa
    41221 tgttgtatgg atatacataa cattatctgt accgacatct gctttcattt gacgaagtgc
    41281 ttcaaggaat ggcaaagatt ctatatcccc tactgttccc cctacttctg taatgatcac
    41341 atctgaatca gtcattttag ctgctcgcat gattttttct ttgatctcat ttgtaatatg
    41401 aggaataact tgaacagttg ctcccaagta ttcgccctta cgttctttac gcaaaacttc
    41461 agaatagatt tttcctgtcg tcacgttgga gtatttgttc aaattgatgt caataaaacg
    41521 ttcgtagtgg cccagatcca aatctgtttc agcaccatca tctgttacga atacttctcc
    41581 gtgctgatat gggctcatcg tccccggatc cacgttgatg tatggatcaa atttttggat
    41641 agttactttt aagccgcggt ttttcaataa gcgtcctaaa gaagctgcaa caatcccttt
    41701 tccgattgat gaaacgacac cgccggtcac aaaaatatat tttgtcataa gttcaaaaac
    41761 tcctttttaa tttatgtgca ggaaaagtct cagacaataa acaaagctcc ctattcttca
    41821 ataagaatag ggagccgaaa tttctgtaaa cttctgaccc tctaaaaggg tgcccaaggt
    41881 gtataataca agctgactaa gggaaagtca agtactcaaa tgaatactat ccgcttacaa
    41941 ttttttcttt ttcgatatcc tttgagaaat tatttcttaa gtcctttatg agtgcaaaaa
    42001 aaatttaacc cacataataa gcttgatata aacatagcta acgttaaacc taagcaaatc
    42061 agaaaatcgt tactgaaaaa ttttaagtga aataatagat aaaaaaataa aacaaacatt
    42121 atgatagata atatcccacc taacaaagaa ctactttttc ctacttgcag caacagttta
    42181 tatagcttat cgtagaaaca atctttttct ttcaccctta tttacctcct ttacgtaaaa
    42241 aacgtagtcc acagttctcg gatttttggc atatcttttc tattaaataa tatcaaaaac
    42301 aaaacaattc cactaatttt ttcaaagatg accttttttt caacaaaagt gccttgtagg
    42361 gattcattga aggtaacgaa tcacataagt aaaaaataag gagatgcgac aaaagtcgtg
    42421 cctccttatt tctaaataaa cggtgttctc ctgccaactc ctcggtcaca agtcacaata
    42481 tccatcaaac atgagaagct gtttttgaaa ttatttcttg tgattcggag ttaaatggta
    42541 ggctcacaac ctctggataa acggtattca aaagccagtt tctcggtatt aagccaaatt
    42601 tatgcaaaaa tgtagaaagc cattttcaca aaatttttct taatactcga aactaaacgt
    42661 ctttttcaaa acctcttggt aaacggtgtt caaaagcttg catctgcggt aataagttca
    42721 gccaattcaa aaacaagaaa agctgttttt gcttggctat tcttattact tgttgcaggg
    42781 cagctttttc acaacctctc cactaaacgg tgttcaatca gctgaccctc ggtattagct
    42841 caaaaaacgg caaaatatga ggaactattt ttccgttagt ttctctaata ctcaggtcaa
    42901 aacgctgatt tcacagcctc taattcacgg tattcctgtt ttaataaagt tctagatatt
    42961 gttctctttc ccactcggaa acagtttgtc tgaatgccgc ccattcgaga cgttttgctt
    43021 caacaaaatt tgagaagata tgttgtccta atgcgtcaat cattacatta tccttacgca
    43081 attctttgat agcattatgg atagttgaag gtaagtcctg gatatgtgca gcttctcttt
    43141 cttcctcatc cattacataa atgttacggt caacagctgc tggcggtgtg atctgattac
    43201 ggataccgtc tagtcctgct tgcaacaata ctgccattgc caagtatggg tttgcagatg
    43261 gatcaactga ccgcaattcc aaacgtgtgg ataaaccgcg agattctggt acacgtacta
    43321 atggcgaacg attacggcca ctccatgcga cataaacagg cgcttcataa cctggaacga
    43381 gacgtttata agaattgact gttggattgc aaacggctgt gtaggcacga gcatgtttca
    43441 gcaaaccacc taagaaatga taagctgttt cacttagttc caattcaccg tctttatcat
    43501 agaaaacatt tccttcatca ttgaacaaag acatattgca atgcatacca gaaccattga
    43561 tcccaaataa cggtttcggc atgaaagtcg cgtgaagtcc atgcttgcgt gcaatcgttt
    43621 tgacaacgag cttgaaggtt tggatattat cacaagcatc taccacatct gcatatttaa
    43681 agtcaatttc atgctgtcct ggcgctactt catgatgtga agcttccact tcaaagccta
    43741 gactttctaa ttccaacacg atgtcacggc ggcaattttc acctaaatct gttggtgcaa
    43801 aatcaaaata accaccttta tcattcaagg tcgttgtgat cccaccgtct tcgtctaatt
    43861 taaataagaa gaattctggt tcaggtccta aattgaaaga ggtaaaacca aggtcgcgca
    43921 tatctttcaa tgctcgtttc aaattcccgc gaggatcgcc ggcaaatggt gtcccatccg
    43981 gattatagat atcacaaatt aaacgagcaa cttttccatg agcactttcc cacgggaaga
    44041 tcatccaagt ggagagatct ggatacaaat acatatcgct ttcttcaatt cgaacaaatc
    44101 cttcaatcga agaaccgtca aacatcattt tattttctaa tactttgtcg atctggctca
    44161 ctggaacttc tacatttttg atcgtaccta agatgtctgt gaacatcaat cgtaaaaatc
    44221 gtacgttttc ttcctcaatg attcgtttga tttcttcacc tgttatctgt ttctttacca
    44281 tggtatccct cttccttttt taatttattc agtcaaagaa ttgtctttgc aatccttgcg
    44341 actgataatg acctgttttg cttaacccac cttgcgccaa aatctcatca cgaaaaattt
    44401 gtcgaacgtc atgatctgtc aacggcttct tgttttttgc ttcttgtttt ttcgcctgtg
    44461 ccatttcgta tacacgtttg atcccagcca tattcaatcc ctctgaaaga tagtctttaa
    44521 tctcaagcaa catatcaata tcattcagcg aatacatacg tcggtttcct tcgcttcgtt
    44581 ccggatgaac taaatcttgt tcttcataat agcgaatttg ccgagcagac aaatcagtca
    44641 gcttcataac tgtaccaatt ggaaatacgg acatagatcg gcgcaattcc ttttctccca
    44701 tcagacgtcc cctttcgttt tataagttgg ctaaagtgta ccaattaaaa aaaatattgt
    44761 caactgcata tgttaggttt tctaacatga gatctctatt ttttataaaa taacaaaaaa
    44821 ataagaacac aaaaaaggta tctagttgat tttcgtacca gatacctttt attttttatt
    44881 atactgtact atcctttatt agtgttttta tt
//
LOCUS       DAZKKZ010000019        41128 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.019, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000019 DAZKKZ010000000
VERSION     DAZKKZ010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 41128)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41128)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41128
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.019"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..1778)
                     /locus_tag="ACG8LA_001103"
     CDS             complement(<1..1778)
                     /locus_tag="ACG8LA_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pLS20_p028 family conjugation system
                     transmembrane protein"
                     /protein_id="HFQ0203417.1"
                     /translation="MKIIEKKIANKKINWLVVNFLVLIAMIIFTSNIAHASIFNWFDD
                     TKSQTEFLNNSLYRPYLKKYNGDFLSQFGIWLGWAVVKGMFTVTDSIQNMIPDVLDLF
                     NFIESTGLNNVYQSAVNTIVIGLMILSLMFVGYKMITGKGTVDLKSVGMNVVMSIALI
                     LLMPTMISSGIQFAKTFYKDSTTITNSDDGVAWSLIKQGVTDLAYINKTDQYSSIDKT
                     EDRNNLTRKNFQQTDLTQVLTDKVIDKLEKENPIADNLRYELVENSNNEFVATKFSDN
                     FLSTFSDSLKSGYYRYQANLWGISIGLTALAIAYVFSAFVIITAILELAFKRVLGVLV
                     FATDIETGQRSKVVLSDILQCYLTVGFQGFGLSMFAMFINFLNSGQGISTNIFIKTIA
                     YICAVFVLIKGSGTVMRYFGVDIGLKEGYGQLASAFGMGAMLFRKGSNGFNRAKGSGE
                     GEDRKPEKNFGETLSKKAGKTGRALGYAHERGLSGLASDGATMASERATKPFKSMRDI
                     ANDTKNKFKEGLDDGTVSAINKNSKPMLAKNKEDETGKYADSVPTRLSDRKDGAKVEN
                     ADRIMSSSERMREAMKNNAESNNNPA"
     gene            complement(1765..1983)
                     /locus_tag="ACG8LA_001104"
     CDS             complement(1765..1983)
                     /locus_tag="ACG8LA_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0203418.1"
                     /translation="MIKNRLIDQVWCLDQNTDSLELIETICFNTIVLDLRAENDNCVT
                     HVIINQKMAQKLSESLRKWAKGGNDENN"
     gene            complement(2059..3111)
                     /locus_tag="ACG8LA_001105"
     CDS             complement(2059..3111)
                     /locus_tag="ACG8LA_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HFQ0203419.1"
                     /translation="MNEKEVESLVEKQGYSNSDIYAELYYQYPIFLNVNEKYKKMKLS
                     SKLVYMLLKDRNRLSLKNNLYDENQKIFLIFEIKNLVEISGMSKNTILSALDELQKVK
                     LLVKRKNGFNKSKMQMFPNFYYLLKPVLCKDDVYKINKITHQENRQKNLIVQNLNYGT
                     NQYSVDSSKFELCDTSMKTRDKNNFADSSKNELELYKSYKDSKDIKESHNDDLLESLS
                     TKNNKLDEELIETFIEENLLKQIWGESIVNCLKLASNSDYRQFDNWYKKFKYAIRSAE
                     KEQKIQLKIIYEICNNKYFVDHVREQLSMTLRDLIRRAKTDHRIKQKDDYIFASLKNK
                     ALELIELQISEGIDKQ"
     gene            complement(3264..3590)
                     /locus_tag="ACG8LA_001106"
     CDS             complement(3264..3590)
                     /locus_tag="ACG8LA_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0203420.1"
                     /translation="MASWLIEEIENERRKIMDAGITVMLDKQQTNQLKNYVFEMTKEA
                     IDQARIDTGLERPFLKGKEMAKYLNVSYTTFLKFKRMGLPVILLEKMELFSKEECKKW
                     ILSHQI"
     gene            complement(3602..3802)
                     /locus_tag="ACG8LA_001107"
     CDS             complement(3602..3802)
                     /locus_tag="ACG8LA_001107"
                     /inference="COORDINATES: protein motif:HMM:NF013540.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0203421.1"
                     /translation="MITLNDQFIRSLRRHRADLILTKNDAAKLIGINRKTYVKIENGS
                     KESIRASTYQKLVNWLLNDLKI"
     gene            3925..4527
                     /locus_tag="ACG8LA_001108"
     CDS             3925..4527
                     /locus_tag="ACG8LA_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFQ0203422.1"
                     /translation="MEFTIGGVTLNRIKFYIDSSKKTIKQISTETGINYTTLTNYYRG
                     ERNPRNTETWNILADYFHVPVSYLMGLDETNSIEQPNLDRIKTARLEKKDKIVKNIAS
                     LDSDYFTELSNLYFSMTSLLEVKLQEDDSDFLFLKSILEDSFEYTILFAKQKKFINKA
                     LNLNIDERKELESELFGNLTQVQVNNLKREITARLISKLQ"
     gene            4582..5748
                     /locus_tag="ACG8LA_001109"
     CDS             4582..5748
                     /locus_tag="ACG8LA_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFQ0203423.1"
                     /translation="MSIQKYTTKSGARYSVRLYVRKDENGKQEYYVKKGFKTEKEAKL
                     HEARKKVEIEDTGYHKPSNDLFITVYEEWLPSYRNRVQETTYQRTKDLFRLHILPKFG
                     NKSISKITPVHCQNAVNEWALKFKNIKQLKSYSSQIFEYAIFAELLHRNPMANTNLPK
                     REKKENENYFSLEELKAFWDILNKEEPLKHILIFQLLITTGIRKGELAALHWSDIYFE
                     EQLMYVRKSYATIRNEEKNARRKTVRIQKNTKNISSERILPIDAQTIEMLKIWKKEQA
                     RELLQFGINTNTKNQLIFTYVNADGDINQPLHADYSNNILKRLEKKYKFKHVTIHGFR
                     HTHATLLLEGGASIKETQDRLGHKNAETTLNTYSHVTEKAQRNALEKFIAYTGL"
     gene            6165..9392
                     /gene="fss3"
                     /locus_tag="ACG8LA_001110"
     CDS             6165..9392
                     /gene="fss3"
                     /locus_tag="ACG8LA_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibrinogen-binding MSCRAMM adhesin Fss3"
                     /protein_id="HFQ0203424.1"
                     /translation="MYKKQKKKLCVLTILSLAVQSIVGAIAPTIAFADEITHPQTVTV
                     ELDLAHQYAVEGTFSDGRPMSEVTVPHYAVYNGVKQDIFCVEPGVPIYNEFTPGYEKN
                     PLPDMSDKAKLVSVLWKKVGTDADTHIVAQKMIWQEVNGYTLHSIKRSDGSAVNIAAI
                     EAKINQAIADYQKKPSFHNSTAKTVLGQSTTVTDTNNLNLSEFDEVVENTANIDYRVN
                     GNQLIISPNANSKESGVLTLKKSAGTGTPVAYKKAGQQTLMAGAIDKPNTYTVKIDVE
                     MEGSLKIKKVDKESGDIIPGTVFHLDFGKTLPAKDVTTDKEGIATLDEIPHGTKVTIT
                     EKSVPAPYTIDTTPMTATIKAGETISVTSKNTREKGQIILDKTGIETGSDLWNDNYSL
                     AGNTFAIRKDSPTGEIVQEMTTDEKGHAETPKEIANALELGTYYVTETKASHGFVNTF
                     KPVKVELNYVNQTVALVTSNVKGQNQEITGETTLTKEDKDTGHETQGKAEFKRAEYTL
                     FTVKDGKAVKWTENFKPELLKGTKASDETVTLTLDEKNQVAVKHLAINEYYWQETKAP
                     EGYTLDETKYPVSIKKVDDSEKNAVITRDVAAKEQVIRFGFDFFKFAGSTTGTAETGF
                     NDLTFKVSPLEGTNEITGAEDEATTAYNEQLGFDGYGKFENLPYGDYLLEEVEAPEGF
                     QKITPLEIRSTFKENKEDYTKSDYIFTITEKGQKQPIKTVTVPYGNLTNENFSVSLNR
                     LMLYDLPEEEDSLTSLATWKEGDKELTTLDSTELVDKLSYNLHEIKEDWYIVAQAIDV
                     DATKAAQEKDKKAKPVAIAETTATLANKEKTGTWEILHKLTVEQVLDKTIVLFNYVYE
                     SKEAYEAGDEPVAKDASLNNQAQTVNCMVERHVSIQTKAHLEEGSQTFTHGDVVDMFD
                     DVSITHDVLDGSKEAFETILYALFPDGTSKEIWKSGKIDYEVNDKEFTKTVLAEKVDT
                     SKYPEGTSFTFKEINYDKDGNINGKHNEDLKEKSQTLTPKKVPTTPSTPEQSEMPTVP
                     SGSQESSPTVKAFPQTGEKTSNVLLFIGFSLIFATAGYYFWNRRN"
     gene            9504..9818
                     /locus_tag="ACG8LA_001111"
     CDS             9504..9818
                     /locus_tag="ACG8LA_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HFQ0203425.1"
                     /translation="MELKFVVPDMVETFGKLTYGGEGEVLSEGYGRNTTIVGRSYHLF
                     SNKQRADDIEVVVAAEAGEKDFDQDQPLKAVNPHLIAKGYEIENRGFTDYVLYVDDLV
                     KA"
     gene            9831..10205
                     /locus_tag="ACG8LA_001112"
     CDS             9831..10205
                     /locus_tag="ACG8LA_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HFQ0203426.1"
                     /translation="MRLTEGIVVDSGLTFGKLRFSALRREVRKQNEDGTVSNEVKERT
                     YNLKSSAQGRMIQVSIPANVPLREFAYDAEVELVNPIVDTVANYVFREGTTVNWFIKA
                     DDLVLKRQLNQGKPTNQNEGKK"
     gene            10215..10559
                     /locus_tag="ACG8LA_001113"
     CDS             10215..10559
                     /locus_tag="ACG8LA_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein J"
                     /protein_id="HFQ0203427.1"
                     /translation="MEINVEHILDCLDQFGKGELTEEQLTNALTYDEKMFLIMHQGLL
                     EVGNDAKEDFDVLDWLGEEESFFMVVEVNESLCRQAESVLEEIDVEMPDAIERFLKQL
                     VETKQLPVVVND"
     gene            10628..11644
                     /locus_tag="ACG8LA_001114"
     CDS             10628..11644
                     /locus_tag="ACG8LA_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsK/SpoIIIE domain-containing protein"
                     /protein_id="HFQ0203428.1"
                     /translation="MYKGHRIRAGDQHLIYHFVLGWLIFLFIGWMSVFYLQELRQFDI
                     SKVSFSTSEIGWSMKDVICLLGSLALSGSMMLLYIHFFQDHWRSLWHRQKLARMILEN
                     HWYEVKQTQGEGFFKDLNSSWTKESISYFPKIYYRMKDGLLSIRVQISLGKYQDQLLK
                     LENKLESGLYCELVEKELKDSYVEYTLLYDMIANRIGIEEIVAENGALRLMKNQVWAY
                     DSLPHMLIAGGTGGGKTYFLLTIIQALLKSDAELFILDPKNADLADLGTIMPHVYSQK
                     EEISECVEDFYERMIARSRSMKEMPNYKTGENYAYLGLPPNFLIFDEYVAYMGANRFP
                     TSIE"
     gene            12238..14112
                     /gene="ltrA"
                     /locus_tag="ACG8LA_001115"
     CDS             12238..14112
                     /gene="ltrA"
                     /locus_tag="ACG8LA_001115"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003964 - RNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0000373 - Group II intron splicing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HFQ0203429.1"
                     /translation="MNVETDEVQGSGKNVGKSVMEVPRLNTKIRYWEYYDLQETFDQL
                     FTQSRNGKKFYQLYELIISENNILLAYRTIKANKGSSTPGTDSFTIDNYKEMNQAEFI
                     HLILSHLENYKPKSIKRVMIPKPNGEKRPLGIPCMIDRMIQQMFKQILEPICEAKFYE
                     HSYGFRPLRSAKHALGRIMYLINISKMHYAVDIDIKGFFDNVNHRLLIKQLWNIGICD
                     KQVLAILSKSLKSPIQGEGIPSKGTIQGGIISPLLSNVVLNDLDHWVSKQWHTFETKY
                     PYTKGYNKFRALRDTNLKQGYIVRYADDFKIMTNDYPTALKWFHAVKLYLKDRLKLDI
                     SNEKSKIVNLRKCKSEFLGFAICVKQKGKKWVCNSRISNKKKDQIKEEIKQRIKDIQK
                     SPTAQNALLFNALVLGVHNYFRYATHINLDLNRMNYVLSFTTYNRLSNCSTRCYPNKA
                     SPTYKKFYSTTMKTYKVAGVYLYPLCDVSTKTIYGFNTEDTPFTPFGRQRLEHKSLQS
                     LVFQELRKLMESKIPNRTVEYLDSRISRYSMKSGKCEITKQFLPAKAVHCHHYLPKSL
                     GGDDKFDNLRIIHKDIHLLIHTTNKMIIDHYVHELKLVPEQIAKINLYRKMCNLQNIQ
                     "
     gene            14214..14594
                     /locus_tag="ACG8LA_001116"
                     /pseudo
     CDS             14214..14594
                     /locus_tag="ACG8LA_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613852.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
     gene            14639..15781
                     /gene="dcm"
                     /locus_tag="ACG8LA_001117"
     CDS             14639..15781
                     /gene="dcm"
                     /locus_tag="ACG8LA_001117"
                     /EC_number="2.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003886 - DNA
                     (cytosine-5-)-methyltransferase activity [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
                     /protein_id="HFQ0203430.1"
                     /translation="MTFLDLFAGIGGFRLGMEQAGHQCIGFCEIDEFARRSYKAIHDT
                     RKEVEMHDITSVSDEFVRSLGPVDILCGGFPCQAFSIAGKRQGFSDTRGTLFFEIARF
                     ATLLQPKFLFLENVRGLLNHEGGATFETILRTLDGLGYDVEWQVLNSKAYVPQSRERI
                     FLIGHSRDACTEQVFPIIGSSSTSDQNIRNLVNINPSNRGMGGQVYGSDSVAPTLTGD
                     EGIKIALPVKDGISVAGMLSGNFEQGNRIYEVTGTAPTLSTKQGGTKIMIRKNETEYQ
                     EVKPGDSVNLAFPNSTSRRGRLGKQSVHTLLTGDQQAVVTDQYQIRKLTPRECWRLQG
                     FPDWAFDRASQVNSDSQLYKQAGNSVTVPVIFDIARRLKGVKAYDL"
     gene            15771..16060
                     /locus_tag="ACG8LA_001118"
                     /pseudo
     CDS             15771..16060
                     /locus_tag="ACG8LA_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297354.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            16316..17500
                     /gene="mobT"
                     /locus_tag="ACG8LA_001119"
     CDS             16316..17500
                     /gene="mobT"
                     /locus_tag="ACG8LA_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MobT family relaxase"
                     /protein_id="HFQ0203431.1"
                     /translation="MAQRNLDYRLLKERRNEYGVSQNKLATACGLSRPYLNQIENGGV
                     IASTKTMRKIFDQLESFNPDLPLTLLFDYVRIRFPTTDVRKIIQEILHLKFEYMLHED
                     YAFYSYQEQYVMGDIVVMLSHEEDKGVLLELKGRGCRQFETFLLAQKRSWYDFFEDCL
                     KAGGVMKRLDLAINDRVGLLDIPDLTKKCQKEECISLFRTFKSYRSGELLKADEKDGM
                     GNTLYIGSLKSEVYFCLYEKDYEQYIKLGIPLDQTETKNRFEIRLKNDRAYYAIQDLL
                     KGRSIESTTFSIINRYLRFADKVDGKRRTNWPLNEQWGRFIGRNRKEIQLTSEPKPYT
                     IERTLNWLGRQVAPTWKMAKELDRLNQTTYIQDMVQNARLSDRHKKILEQQSMAIENL
                     IV"
     gene            17497..17610
                     /locus_tag="ACG8LA_001120"
     CDS             17497..17610
                     /locus_tag="ACG8LA_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HFQ0203432.1"
                     /translation="MKRGILMEIVKDMLLVLGGSMLGVTVMCLMNASAAAD"
     gene            18380..20290
                     /gene="ltrA"
                     /locus_tag="ACG8LA_001121"
     CDS             18380..20290
                     /gene="ltrA"
                     /locus_tag="ACG8LA_001121"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003964 - RNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0000373 - Group II intron splicing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HFQ0203433.1"
                     /translation="MPKNKNETLCVEDLRHAEYYEMQNTFDDLYAKSKNGDIFTHLMD
                     IILSRENILLAYRNIKANAGSKTAGTDGTIIKDIGKLPAETVVKKVRYIVAGSPHGYR
                     PKPVRRKEIPKPNGKTRPLGIPCMWDRLIQQCIKQVLEPICEAKFSENSYGFRPNRSV
                     ENAIKATYNRLQISQLHYVIEFDIKGFFDNVNHSKLIKQIWAMGIRDKHLIFILKRIL
                     KAPIKMTNGTITYPEKGTPQGGIISPLLANIVLNELDHWVESQWQENPVTKNYVVHIN
                     KSGSPCKSNAYKEMKKTKLKEMYMVRYADDFRVFCRYKESAEKAKIAITQWIEQRLKL
                     EVSQEKTRIVNVRKRYSDFLGFKIKMIPRRKKLVVKSHISDKQFKNQKDKLVSQAKKI
                     ASPSKGKTELEETRLYNSMVLGMQNYYQIATNVNLDCMKLNRAVMAIFTNRLGTNKRG
                     RLRKTGRQLTTKEATRYGKSKMLRYVAGEGEPIFPVGYIQHRKPMAKVYLANCYTLEG
                     RKFIHTNLSVDKLLMYQLMKLSLENRTIEYADNRISLFSAQHGKCAITLEEFQQANEI
                     HCHHIVPTGAGGNDDYKNLILVKEAVHRLIHAKTEETIQKYIALLKLNKVQLIRLNKY
                     RVLAGNQELNLI"
     gene            20394..20618
                     /locus_tag="ACG8LA_001122"
     CDS             20394..20618
                     /locus_tag="ACG8LA_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002570387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0203434.1"
                     /translation="MSGTYLSIYQWFLTNAQSLVLLAIVVIGLFLGFKREFSKLIGFL
                     VIALIAVGLVFNASGVKDVLLNLFNRIVGA"
     gene            20631..21134
                     /locus_tag="ACG8LA_001123"
     CDS             20631..21134
                     /locus_tag="ACG8LA_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HFQ0203435.1"
                     /translation="MEQMRVYIANLGKYNEGELVGAWFTPPVDFDEVKEQIGLNDEYE
                     EYAIHDYELPFEIDEYTPIEEINRLCNLAEELEGTPIGEAASEIQHAFFNSFEEMVEH
                     VDDIVYYPDCDDMSDVAHYLIVEAGDFGEVPEQLKPYIDFDACGRDLEIGGNYLVTSR
                     GVFEYPE"
     gene            21261..22298
                     /locus_tag="ACG8LA_001124"
     CDS             21261..22298
                     /locus_tag="ACG8LA_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic GMP-AMP synthase DncV-like
                     nucleotidyltransferase"
                     /protein_id="HFQ0203436.1"
                     /translation="MANIQTSFIDFHNSIRLDVEDNTLLKDYKDQVIDGLKDYLPDDV
                     KFETFLQGSYSVYTGIKSCDEKIDFDIDIAVAFEIDHTVYEDPREPKLWVKEALVEIF
                     PNAQVNLKVPCVTATFTGKKTKKNVHVDVAVYAKEDENYFLAKAKEFSAPENRCWEEA
                     DPKVLKEKINSHVADSDDRKQFRRCIRYLKRWKDNNFNQEYKPTGIGLTINVMDTFLV
                     NKSTDFLTRKVQYNDMECMKQIVSSLKDSFVYEYSETDGWHYRLHAYLPVKPNSDTYS
                     KMTVNQMSDFKNKLSKLYDDLIFAIDTEDEYEATKRLNNQFGEDFLIISEEEVTEKNL
                     RNAFVTDYPSA"
     gene            22313..24010
                     /locus_tag="ACG8LA_001125"
     CDS             22313..24010
                     /locus_tag="ACG8LA_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="E2/UBC family protein"
                     /protein_id="HFQ0203437.1"
                     /translation="MDYTDILKEKLTDVVRLFDGNYYGDFSFATIGKLRLKIEIPKHF
                     PLVLPRIYIHNFDHLGLYLPHVEKDGLVCFSSDINYLVDEENSELVLLQCVNKTIKTI
                     EEGLKGLNKNDFRKEFVAFWDKQENQISLFYLCEPALFIKSVDTIMYGKSLVALDKEN
                     ELQLNAASRLFNGEKEDTHELDAYYVPIRNKNNIMPPKNNKAWSKKDILQIVKKNVTG
                     ANKRFFLKLEKRKNRHNVLLILDIPIEEKSNNVIIGFLFTKQSGSIKDYKGTPRTVLV
                     QRHDELYLVNRTSGENYGLGANIAIVGVGSVGSKIAENLGPLGVRKMTLIDNDCFQAE
                     NLYRNSLGADSLKNARSQNNFFKVDLMQEELEKKIPYLCVEVESMNVLDLISMQPGFF
                     KEYDYVFVCIGDTMASLALNNYFSKSSQKVFYSWLEPYGIGGHTLFINYSLNQKGCFN
                     CLYTDSNSKNRCSNRASLVKEGQIFERTLASCRSKFIPYNAIASTECAINAIKLFHKV
                     NQNNMTNSTLFSWIGDGSTFENLGYQYSDRNTFLNGVNKFEERFFSKYCKVCGELDD"
     gene            24003..24464
                     /locus_tag="ACG8LA_001126"
     CDS             24003..24464
                     /locus_tag="ACG8LA_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mov34/MPN/PAD-1 family protein"
                     /protein_id="HFQ0203438.1"
                     /translation="MIKFSCDRIVIEVRDEVLKIFEQYRQGKDDLPEAGGVLHGKRLK
                     NGSIIITDITTPQIGDIQKRLLFKKNREIHQQLSNEKWIESNKFSIALGEWHTHPEAV
                     PTPSNVDKKSWRLNVSKQHDDRVYVFIIVGFSDLRMWLLSKKSDIRQAIKL"
     gene            24477..25337
                     /locus_tag="ACG8LA_001127"
     CDS             24477..25337
                     /locus_tag="ACG8LA_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0203439.1"
                     /translation="MKSQKNIWWWGFLVGKVMIPALLLISLPMITFFFTNKKMSKEAV
                     IFFFGDQKATFIETLVTSLQLNLNYIFSIIIVISLLNFFKKRNSGKVFNSNGNVYYNY
                     FYFVFWVAATLLGYDKIQIAGIPIHMQYKLVLSGIFSEVLPDIYDDHYDSDGTCKVSI
                     EKENFDDIDGYDSVNLLIIDTYDIKMSELSMENQTYPTIIVRGNSIDGVRKVNRSLIL
                     EIKKTMDEIQKSDFKKVFVASTSNPKNSINIINSSFRFFGRSRRFKLYVLQKDYASNG
                     KYSKKYRIFI"
     gene            25375..25764
                     /locus_tag="ACG8LA_001128"
     CDS             25375..25764
                     /locus_tag="ACG8LA_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HFQ0203440.1"
                     /translation="MKKIKSYTSIWAVEKVIYAINDFQLPFPVTFNQMAWFVLSLMFV
                     IVFAHVPPLSMIEGAFLKYLGIPIAVTWFMSQKTFDGKKPLGFLRSFISYHLRFKVTF
                     AGKKVKEQKKRWDEPITLVRSVNYVPD"
     gene            25751..28198
                     /locus_tag="ACG8LA_001129"
     CDS             25751..28198
                     /locus_tag="ACG8LA_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFQ0203441.1"
                     /translation="MYPIKYIENNLVFNQEGECFAYYELVPYNYSFLSPEQKYQVHDN
                     FRQLIAQNREGKIHALQIATESSIRATQERSKKEITGRLKEVAKQRIDLQTDALVSMI
                     GDSQIDYRFFIGFKLISTDEEVNLKNLRKSFFSGLQEFVYGVNHHLMGDFVSLSNEEI
                     RRYTKLEKLMESKLARRFKVKRVTPSDLTYLIEHIYGEKGTPFEEYEFQLPKKKLKSE
                     TLVKRYDLLRPTRCLIEEKPRYLRMEHENHESYVAYLTINTIVGEMEFPSSELFYYQQ
                     QQFTFPIDTSMNVEIVTNKKALATVRNKKKELKDLDNHAYQSDNETNSNVLDALDSVD
                     ELETTLDQSKESMYKLSYVVRVSAKSVDELKRRCDEVLDFYDDTNVKLVRPFGDMMGL
                     HKEFLPSSKRYMNDYIQYVTSDFLAGLGFGATQMLGELEGIYFGYNVDTGRNVYLKPA
                     LASQGVKGSVTNALASAFLGSLGGGKSFSNNLLVYYAVLFGGQAVIVDPKGERGGWKE
                     TLPEIADEINILNLTSKPENQGLLDPYVIMKKKKDSESLAIDILTFLTGISSRDGEKF
                     PVLRKAIRTVTQSDQRGLLQVIVELRKEDSPVAENIADHIESFTDYDFAHLLFSDGSI
                     TQSISLDKQLNIIQVADLVLPDAETTFEEYTTMELLSVSMLIVISTFALDFIHSNREI
                     FKIVDLDEAWSFLQVAQGKTLSNKLVRAGRAMNAGVYFVTQNSDDLLDERLKNNIGLK
                     FAFRSTDIHEIKKTLEFFGLDKEDESNQKCMRDLENGQCLMQDLYGRVGVVQVHPVFE
                     ELFHAFDTRPPVQERME"
     gene            28203..30311
                     /locus_tag="ACG8LA_001130"
     CDS             28203..30311
                     /locus_tag="ACG8LA_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CD3337/EF1877 family mobilome membrane protein"
                     /protein_id="HFQ0203442.1"
                     /translation="MKKKLFRIFGIVLISLVTLIILLSLVGTVAEATGLVDDTVGAGN
                     LYSQYSLGNYQLDFFVDSSWDWLPWNWGDGLGKSVMYGLYAITNFIWTVSLYLSNATG
                     YVVQEAYKLDFISDTAESIGKNIQTLAGITENGLQTSGFYFGFLLLMILALGVYVAYT
                     GLLKRETTKAVRAVINFVMIFLLSGSFIAYAPTYITKINDFSSDVSEAALSLGTEIVV
                     PNSESQGKDSVDLIRDSLFSIQVQQPWLLLQFDDSNIEEVGEDRVNKILSVSPDENKG
                     KDREEAVKAEIEDNDNANLSITKTMNRLGTVVFLVLFNIGISFFVFLLTGIMLFSQIL
                     FIIFAMFLPISFLLSMLPTYESLGKKAIIRLFNTIMMRAGVTLVITTAFSISTMFFNI
                     SATYPFFMVAFLQIVTFAGIYFKLGDIMNMFNLQSNDSQSMGRRVMRKPQMLMNRTLR
                     QLNRNVGRTLAFGGGAAVGNKLAKEQSKSKFKPSGSSLRKNSRLPNDHEIPSDLNKEK
                     PIPNNKKQSRMNLAGRKVGKVLDTQALVKDKTKQVKDGVRNTPTNLKYNFHKGIEKTK
                     KAPEEFKRGLVQEKANRGELREKQQQRRDEKIAEKRKVLNEIGNPHGKRRENVPIKAK
                     VQSQKDRAPKRIVRANSNPEIKRKFASQEIISKGINQSSSKKNSFQQVKRRSTLSKRT
                     NRKVQKSLNPHPKPRSGEKK"
     gene            30308..31312
                     /locus_tag="ACG8LA_001131"
     CDS             30308..31312
                     /locus_tag="ACG8LA_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HFQ0203443.1"
                     /translation="MNVKKLSAISLTFLTISFMGILMCVGLLFGEDSEGSSSSGAPPG
                     GSSVSEEVLKHRAMVEKYAKESDITEYVPILLAIIQVESGGTMEDVMQSSESAGLPPN
                     SLSTEASIKQGCLYFASLVKRSKELGCDQDSIIQAYNFGGGYLDYVAKNGKKHSFALA
                     ESFSKEKSCGQKIDYPNPIANKENGGWRYNYGNMFYCLLVKQYLTTTQFDDKTVQGIF
                     DEAFKYEGTAYVFGGSRPETGFDCSGLTQWCYAKVGLKLPRVAQDQYDAMTHIDLKDA
                     KPGDLVFFHSTYDAGTYVTHVGIYAGENRMFHAGDPVGWTNLTESYWQQHLIGAGRYK
                     "
     gene            31331..32242
                     /locus_tag="ACG8LA_001132"
     CDS             31331..32242
                     /locus_tag="ACG8LA_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HFQ0203444.1"
                     /translation="MKIKIERNQKEKSLKKKKERVVSVGKHRKMVLALWLLLSCSLTF
                     GVYKNFTAIDQHTTHEKVVIKEKVVNTSGIENFTKDFSKEYFSWKNNKEAIEKRMNNL
                     EQYLTEEGFALSQDMVRADIPTNSEVQSVKVLDVEKSSEEFVVSFLVEQKITEGKKAQ
                     SISSAYRVTIFEDENRNYIVTSLPTMIAKPDRAKYKTKQVENDSKIDAKTTEEIAEFL
                     ETFFKLYPSASEKELEYYVENDAMRPINIDLKFSKLEDPVYLQNGKKILVSTKIKYLD
                     NVSKTTSYFQYKLILQKNGNWKIIDVK"
     gene            32429..32716
                     /locus_tag="ACG8LA_001133"
                     /pseudo
     CDS             32429..32716
                     /locus_tag="ACG8LA_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(32904..33119)
                     /locus_tag="ACG8LA_001134"
     CDS             complement(32904..33119)
                     /locus_tag="ACG8LA_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0203445.1"
                     /translation="MNAGIADMNLIKKTLNDFTSNSISKGTGINLSTIKKLKSGERSV
                     EKLNLLDAIKITEFAMKNGKAEIEIWR"
     gene            complement(33378..33587)
                     /locus_tag="ACG8LA_001135"
                     /pseudo
     CDS             complement(33378..33587)
                     /locus_tag="ACG8LA_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
     gene            complement(33890..35329)
                     /locus_tag="ACG8LA_001136"
                     /pseudo
     CDS             complement(33890..35329)
                     /locus_tag="ACG8LA_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297342.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
     gene            complement(35877..36548)
                     /locus_tag="ACG8LA_001137"
     CDS             complement(35877..36548)
                     /locus_tag="ACG8LA_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AP2 domain-containing protein"
                     /protein_id="HFQ0203446.1"
                     /translation="MKERYGHLTVVEEITHNGYKKYRYLCDCGNETIVYRSNLLSGRT
                     KSCGCGNYKNRHKYKNLTNKTFGKLVAIKPTKLRSEGTVVWECQCLCGRKKLVSAKRL
                     LKGDVKSCGCLKSKKHHIENKKFGLLTAKYPLDNNCSWKTKWVCQCECGSMCEISYSN
                     LFFGHTQSCGCLKRQETRTCVEGTVIECLTSKLPKNNTSGVKGVYRSKEKWIAYITLK
                     KRGTI"
     gene            complement(36897..38348)
                     /locus_tag="ACG8LA_001138"
     CDS             complement(36897..38348)
                     /locus_tag="ACG8LA_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HFQ0203447.1"
                     /translation="MKKSLKLASAVILMSQLFIATPFHVLASENSTYKIAKERTETTE
                     MSNSDVTAESSELLTTLSSESSTTSNAESSTTSSSESSTTSNAESSTTSSSESSTTSN
                     AESSTTSSSESSTISSAESSTTSSSTSEITSSKVTRPNHIESSKKEAPKTEGQTKNFS
                     TPQQIESTESFQSQPILSGNEEIHFDKNESVENFIMKIGESARKIGQKYDLYASVMIA
                     QAILESASGQSQLAQAPNYNLFGIKGTYNGNFVIMVTNEDLGNGTLYTTQSKFRVYEN
                     YEESFEDYAKLLTKGISGNKDFYAGALKANSKTYREATKFLTGRYATDTQYYLKLNEL
                     IKTYDLTNYDKEVKGPQMSKTGYQVPIHNYSITSLFGNRGNEFHRGLDMAATQGEPIH
                     AVKAGKVVKAEFHYSWGNYVVIQHEDGSTALYAHQQQYLVKTGDNVLQGQIIGYVGST
                     GNSTGPHLHLEICKDSSLSQSMLVDPKTLLFGD"
     gene            complement(38460..39803)
                     /locus_tag="ACG8LA_001139"
     CDS             complement(38460..39803)
                     /locus_tag="ACG8LA_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HFQ0203448.1"
                     /translation="MKKIVIIGSNHSGLAAARFLNLCDSNYEVILIDKKSEISYLECG
                     TSLFIKREVSNLEDLFYQNRRELNSKIKKLFLETAVDKIDIQNKKIICVKKDGTRFSQ
                     EYDKLILATGSKQIMLDVPGNNLANIFSIKNFPNAKEIFKALDDNTIKKVGIIGAGYI
                     GVEIAEAIRKRGKEVYLFDVADRVLSTYYDRSFSDKVEEILSKNGIHLCLSESPKKYL
                     GRKKIEKIVTTSGTQYSMDMVVQAIGFLSNSPIGKKELLRDVSGAYLTNEYQQTNIKD
                     IYAIGDCATTFFTSINRSSVDFSISNALRTAYIATQHIDNQDFTPSGSQFTNGFSIFN
                     YNFYAAGLNLKTARLLSESIDYIEIEDFIRPVFLRKNSRVKLRISFEKNTKRIVGVQL
                     CSQEDLSGLLSMFSLAIEEQITLDKLKMLDYLFHPSFSQPYNFILKAVTGLNIET"
     gene            complement(39937..>41128)
                     /locus_tag="ACG8LA_001140"
     CDS             complement(39937..>41128)
                     /locus_tag="ACG8LA_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="Rib/alpha-like domain-containing protein"
                     /protein_id="HFQ0203449.1"
                     /translation="SDADKYNPEGQKVTTELNKEPDASEGIKNKEDLPKDTKYTWKEK
                     VDVSAAGNKKGTVVVTYPDGSSDEVEVDVTVTDNRSDADKYEPTVEGEKVEVGGTVDL
                     TDNVTNLPTLPEGTTVTDVTPDGTIDTNTPGNYEGVIEVTYPDGTKDTVKVPVEVTDN
                     RSDADKYNPEGQKVTTDLNKEPDASEGIKNKEDLPKGTTYTWKEKVDVSTAGNKKGIV
                     VVTYPDGSKEEVEVTISVEDKKAPNKPQVDPITEGDQIVTGKTEPNAEVTVTLPNGSQ
                     YHGTADKNGNFTVKVPKLEAGTKVIVTATDESGNTSEPTNVVVSSNEKDSEKAVSKDN
                     KTDNQGSKQNKNRGKSSPQKQSSKAYPKTGEIDSNIFTISGGLILLGTLGLLGYKNRK
                     KENE"
BASE COUNT        13577 a         7019 c         7820 g        12712 t
ORIGIN      
        1 cttgcaggat tattattcga ttcagcatta tttttcattg cttcacgcat acgttcagaa
       61 ctagacataa ttctatcggc attttcaact ttagcaccat cttttctatc tgaaagacgt
      121 gttggcacgg aatcagcata ttttccagtt tcatcttctt tatttttagc taacataggt
      181 ttgctatttt tattaatagc ggacactgta ccatcatcta aaccttcttt aaacttattc
      241 ttggtatcat tagctatatc acgcatactc ttaaatggtt ttgttgctct ttcactagcc
      301 attgtagctc catctgaagc taaaccggat aatccacgtt catgggcata tcccaaagct
      361 cttccagttt tgccagcttt ttttgataga gtttcgccga aattcttttc tggttttcga
      421 tcttctcctt ctccgcttcc tttagcacga ttaaatccat ttgatccttt tctaaacagc
      481 attgcgccca ttccaaaagc agaagcaagt tgcccatagc cttctttgag tccaatatca
      541 acaccaaagt atctcatgac tgttccactg cctttgatta aaacaaaaac ggcacagata
      601 taagcaattg tttttataaa aatatttgtt gagatacctt gtcctgagtt cagaaaattg
      661 ataaacatag caaacattga taacccaaat ccttgaaacc caacagttaa gtaacattgt
      721 agaatatctg atagaacaac ttttgaacgc tgtcctgtct caatatctgt tgcaaaaaca
      781 agaacaccta acacacgttt aaatgcaagt tctagtattg ctgtaatgat cacaaacgcg
      841 ctgaacacat aggcgattgc taacgctgtc aacccaattg aaatccccca tagatttgct
      901 tggtatcggt aatagcctga tttcaagcta tcagaaaatg ttgataagaa gttgtcagaa
      961 aactttgtag caacaaattc attattagaa ttttcaacta attcataacg aagattgtcc
     1021 gcaattggat tttctttttc caatttatca atcactttat ccgttaacac ttgtgtgaga
     1081 tccgtctgtt gaaaattttt tcgtgttaaa ttatttcgat cctccgtttt atcaatgctt
     1141 gagtactgat ctgttttatt aatatatgct aaatctgtta ctccttgttt tatcaatgac
     1201 caagcgactc cgtcatctga atttgtaatc gtagtagagt ccttataaaa tgttttagca
     1261 aattgaatac cactagaaat catggttggc attaaaagta ttaatgctat agacatcact
     1321 acgttcattc caaccgattt taaatccact gttccttttc cagtaatcat tttgtaacca
     1381 acaaacatca atgaaaggat cattaatcca atgacaattg tatttacggc tgattgataa
     1441 acattattta gccctgtact ttcaatgaaa ttgaacaaat ccagcacatc tggaatcata
     1501 ttttgaatcg aatctgtcac agtaaacatg ccttttacca cagcccatcc gagccaaatc
     1561 ccgaactgac taaggaaatc tccattgtac ttttttaggt aaggtctata aagagaatta
     1621 ttcaaaaact ctgtttgact ttttgtgtca tcaaaccaat tgaaaatact cgcatgagca
     1681 atattacttg taaaaataat catagctatc agaacaagaa aattaacaac caaccaattt
     1741 atttttttat tggcaatctt tttttcaatt attttcatcg ttacctccct tagcccattt
     1801 tctgaggctc tcagagagct tctgagccat tttttgatta attatgacat gagttacaca
     1861 attatcattt tcagctctta aatcgagaac tatagtgttg aagcaaatag tctcgattaa
     1921 ttcgagacta tctgtatttt gatctagaca ccaaacttga tctattaaac gatttttaat
     1981 caaaataacc cctcctatat tcaaagttct caaatgaagt ggagataccc ctccatttca
     2041 tttgactcaa ttctattctt attgcttatc tattccttcg ctgatttgca attcaattag
     2101 ttctaacgct ttatttttta gagaagcaaa gatataatcg tctttttgtt tgatacgatg
     2161 atctgttttt gctcttcgta tcaagtcacg taaagtcatt gatagctgtt ctctaacatg
     2221 atctacaaaa tacttgttat tacaaatttc atagataatt ttcagttgaa ttttttgttc
     2281 tttttcagca gatctaatcg catatttgaa ttttttgtac cagttgtcga attgacgata
     2341 atcactattg ctagccagtt ttaagcaatt cacaatactt tctccccata tttgtttaag
     2401 aagattttct tcaataaatg tttcgatcaa ttcttcatct aatttattat ttttagttga
     2461 aagtgattca agaagatcat cattatgtga ttctttaata tctttactat ctttataaga
     2521 cttatataat tctagttcat tttttgaact atcagcaaaa ttgtttttgt ctcttgtttt
     2581 cattgatgtg tcgcatagtt caaattttga actatcaaca gaatattgat ttgttccata
     2641 gttcaaattt tgaactatca agtttttttg tctattttct tgatgggtta tcttattaat
     2701 tttataaaca tcatctttgc acagaacagg ctttaacaaa taataaaaat ttgggaacat
     2761 ttgcatttta cttttattga agccattttt tcttttcaca agaagtttaa ctttttgaag
     2821 ttcatctagt gctgataaga ttgtattttt tgacattccc gaaatttcta cgagattttt
     2881 gatttcaaat atcaaaaaaa ttttttgatt ctcatcatac aagttatttt tcaatgaaag
     2941 tctatttcta tcttttagta acatataaac taacttagaa cttagtttca ttttcttata
     3001 tttttcattt acgtttaaaa aaataggata ttgatagtat aattctgcat atatatcaga
     3061 attagaatag ccttgctttt caactaagct ttcaacttct ttttcattca ttgtcacacc
     3121 tgcttctgat tttatttgct ataatagatt caaataaagt tttctcagaa ctttattatt
     3181 gagtgttccc ccgatctgca aactgacggg aacactcttt ttaatttttt ctacttcatc
     3241 aaatttaaaa aacgaggtgt tttttaaatt tgatgactca atatccattt tttgcattct
     3301 tcttttgaaa acaactccat tttttctaat aaaataactg gcaatcccat tcttttaaat
     3361 ttcaaaaaag ttgtatatga tacattcaaa tatttagcca tctcttttcc ttttagaaat
     3421 ggtctttcta atccggtatc aattcttgct tgatcaatag cctcttttgt catttcaaaa
     3481 acataatttt tcaattgatt cgtttgttgt ttatctaaca ttactgtaat tcctgcatcc
     3541 attatttttc tcctctcatt ttctatttct tcaatcagcc aactcgccaa gttgtattta
     3601 tttagatttt caaatcatta agtaaccaat ttaccaactt ttgataagta gatgctctaa
     3661 tactttcttt gctcccattt tcgattttga catatgtttt ccgatttata cctatcaatt
     3721 ttgctgcatc gtttttagta agtataagat cggctctatg tcttcttaag cttctaatga
     3781 attgatcatt aagagttatc attcagcgcc tcctttcaaa ttattcactt tgtggttttt
     3841 atcttaataa gcacatttta aaccacaaaa cgagtaatat caattaaaat attactcaat
     3901 ttgtggtttt catgctataa tagtttggaa tttactatag ggggcgttac tttgaataga
     3961 ataaaatttt atattgattc cagtaaaaag accattaaac aaattagtac agaaactggt
     4021 attaactata caactcttac gaactattac cgtggtgagc gaaatcctag aaatactgaa
     4081 acatggaata tccttgctga ttatttccat gttcctgtaa gttatttgat gggattagac
     4141 gaaacaaatt ccatagaaca acctaatctt gatagaataa aaactgctcg tttagaaaaa
     4201 aaggacaaaa tagtcaagaa tattgccagt cttgactcag attattttac tgaattatct
     4261 aatctatact tttccatgac ttctttactt gaagtcaaac ttcaagaaga tgactccgac
     4321 tttctttttt taaaaagtat tctagaggac tcctttgaat acacgattct atttgccaaa
     4381 caaaagaagt ttattaataa agctttaaac ttaaatatcg atgaaagaaa agagttagaa
     4441 tctgagttat ttggcaactt aacccaagta caggttaaca atctaaaaag agagataaca
     4501 gctcgattaa tatcaaaact tcaataaaac taattattca atcagccaac tcgccaagtt
     4561 atcagattgg agagattagt tatgtcaata caaaagtaca caacaaaaag cggtgcacga
     4621 tatagtgtcc gcttgtatgt tcgtaaagat gaaaatggaa agcaagaata ctatgtaaaa
     4681 aaagggttta aaactgaaaa agaagccaag ttacacgaag caagaaaaaa ggtcgagatt
     4741 gaagataccg gctatcataa gccttctaat gacttgttta taacagtgta tgaagaatgg
     4801 ttgccttctt ataggaatcg tgtacaagaa acgacatatc aacgtacaaa agaccttttc
     4861 cgcttgcata tactaccaaa attcgggaat aagtccattt ctaagattac tcctgttcac
     4921 tgtcagaatg cagtcaatga atgggcttta aaattcaaga atatcaaaca gcttaagtct
     4981 tacagctctc aaatatttga gtatgccatt tttgcagagc tattacaccg aaatcctatg
     5041 gcaaatacaa atctaccaaa gcgggaaaag aaagaaaatg aaaattactt ttcattagaa
     5101 gaactaaaag ctttttggga tattctcaat aaagaagagc ctttaaaaca tattttaatc
     5161 ttccagcttt tgattactac tggtatacgt aaaggagagc tagctgctct tcattggtct
     5221 gacatttatt ttgaagaaca gctaatgtat gttagaaaga gctatgcaac tattcgaaat
     5281 gaagagaaga atgcaagaag aaaaactgtc aggattcaaa aaaatacaaa aaatatatct
     5341 tccgaacgaa tattaccaat tgatgcacaa actattgaaa tgttaaaaat ctggaaaaaa
     5401 gaacaagctc gagagctttt gcagtttggc ataaatacaa atacaaaaaa tcaacttatc
     5461 tttacctatg taaatgcaga cggtgacatt aatcaacctt tgcatgcgga ctattcaaat
     5521 aatatattga aacgtttaga gaagaaatat aaatttaagc acgttactat tcatggattc
     5581 cggcacactc acgctactct tctactagaa ggtggagcaa gtatcaaaga aacacaagat
     5641 cgattgggtc ataaaaatgc tgaaactacc cttaacactt attctcatgt tactgaaaaa
     5701 gctcaacgaa atgcgttaga aaaattcatt gcttacactg gtttataata ttgtcattac
     5761 ctttctcatt accagaacga aaaaaagaca ccttctcgca atgagaaagt gtctgaaatc
     5821 gttggtataa caacgattaa cgttttgaaa actgtgaagc tttacgtgct ttcttaagac
     5881 ctggtttttt cttcgtatca ttgaataagt ttgaaaagcc ttgatttata aaggtttttc
     5941 cgtaaatata ttttgttata tttgattaaa tttgaaatgt ttgtgttcta aaatgtgttc
     6001 taatttaaag gcagtatatt tcgtatttta tattaaattt ttaggctcat tcattctcaa
     6061 atccattcta tttagtcaat aaatatttta aaaagacttt ataaacaaag atgttcaagc
     6121 gagcatctta tttttttgtg cctaatttga aaggagaaca tttcatgtat aaaaaacaaa
     6181 aaaagaaatt atgtgtatta actattttga gtttggctgt tcaatcaatt gtaggagcaa
     6241 ttgctcctac gattgctttt gctgatgaaa ttacccatcc acaaacggta accgtagaac
     6301 tagatttagc acatcaatat gctgttgaag gaacttttag tgatggtcgt ccaatgtcag
     6361 aagtcactgt tccgcattat gcagtgtaca acggcgttaa acaagatatt ttctgtgttg
     6421 aaccaggagt cccgatttac aatgagttca ctcctggata tgagaagaac ccgttaccag
     6481 atatgtccga taaagccaaa ttagtttccg ttttatggaa aaaagtaggt acagatgcag
     6541 atactcatat tgtggcacag aagatgatct ggcaagaagt taatgggtat acccttcact
     6601 caataaaacg atcagatggt agtgccgtaa atatcgcagc cattgaggca aaaatcaatc
     6661 aagccattgc cgattatcag aagaaaccaa gcttccataa tagtacggct aaaacagtat
     6721 tagggcaatc gactactgtg acggatacga ataatctgaa tttgtcagag ttcgatgagg
     6781 ttgtggaaaa taccgcaaac attgattatc gtgtgaatgg caatcagttg ataatcagcc
     6841 caaatgccaa ttcaaaagaa agtggtgtgt tgacgcttaa gaaatctgct ggtaccggaa
     6901 cacctgtcgc ctataaaaag gctggccaac agactttaat ggccggggcg atcgataagc
     6961 cgaacactta tacggtcaaa attgatgtgg aaatggaggg ttctttgaag attaaaaaag
     7021 ttgataaaga atcgggtgat attataccag gaacggtttt ccatttagac tttggaaaaa
     7081 ctttacccgc aaaagacgtg accaccgata aagaaggcat tgcgacctta gatgagattc
     7141 ctcatggtac aaaggtaacc attactgaaa aatcggtgcc ggcgccttat acgattgata
     7201 ccacacccat gactgccaca attaaagcag gtgaaaccat ttcagtgact tcaaaaaata
     7261 cgcgagaaaa aggtcaaatt attctggata aaaccggaat tgaaacaggg agtgatcttt
     7321 ggaacgataa ttactcttta gcgggcaata cgtttgccat tcgcaaggat agcccaactg
     7381 gtgaaatcgt ccaagaaatg accacggatg aaaaaggtca tgcagaaaca ccaaaagaga
     7441 ttgccaatgc gttggaattg ggaacctact atgtgactga aaccaaggct agtcatggct
     7501 ttgtgaatac tttcaaacca gtaaaagtcg aattgaatta tgtcaatcaa acagtggctc
     7561 ttgttaccag taacgtaaaa gggcaaaacc aagaaattac tggtgaaacc actttgacaa
     7621 aagaagacaa agataccggt catgaaactc aagggaaagc tgagtttaaa agagctgaat
     7681 acaccttgtt tactgttaag gatggaaaag cggtcaaatg gaccgagaac tttaaaccag
     7741 aattgttgaa gggaacgaaa gcttctgatg aaaccgtaac tttgacttta gatgaaaaga
     7801 atcaagttgc cgttaaacac ttagcgatta atgagtatta ctggcaagaa accaaagcgc
     7861 ctgaaggata taccttggat gaaacaaagt atcctgtatc catcaaaaag gtggatgata
     7921 gcgaaaaaaa tgctgtgatt actcgagatg ttgcggcaaa agaacaagtg attcgctttg
     7981 gctttgattt ctttaaattt gctggatcaa ctactggcac tgccgaaact ggcttcaatg
     8041 atctaacctt taaagtgtcg ccattggaag gaaccaatga aatcaccggt gccgaagatg
     8101 aagcgaccac agcttataac gagcaattag ggtttgatgg ttatggcaag tttgaaaatc
     8161 ttccttatgg ggattattta cttgaagaag tagaagcccc agaaggtttt caaaagatta
     8221 cgccattaga aatccgttct acttttaaag aaaataaaga ggattatacc aagagtgatt
     8281 atatctttac tattaccgaa aaagggcaaa agcaaccgat taaaacggta acggtccctt
     8341 atgggaatct aaccaatgag aatttctcag tcagtttgaa ccgtttgatg ctttatgatt
     8401 tgcctgagga agaagatagc ttaacttctc ttgcgacttg gaaagaagga gataaagaat
     8461 tgactactct tgattctacc gagctagtcg ataaattgag ctataatcta catgaaatca
     8521 aagaagactg gtatatcgta gctcaagcca tcgatgtaga tgctacaaaa gctgcccaag
     8581 aaaaagataa aaaagccaaa ccggtggcga ttgcggaaac aaccgcaact ttagcgaata
     8641 aagagaaaac aggaacttgg gagattctgc ataaattaac tgtcgaacaa gttttagaca
     8701 agaccattgt cttattcaac tatgtgtatg aaagcaaaga agcctatgaa gctggtgatg
     8761 agccggtagc gaaggatgct agcttgaaca atcaagcgca aactgttaat tgtatggtgg
     8821 aacgtcatgt ttccatccaa accaaagcgc acttagaaga aggttctcag acctttactc
     8881 atggtgacgt ggtagatatg tttgatgatg tatccattac ccatgatgta ctagatggct
     8941 caaaagaagc ttttgaaaca attctgtacg ctttatttcc agatggtaca agtaaagaaa
     9001 tttggaaatc tggcaagatt gattacgaag tgaatgacaa agaatttacc aaaaccgtac
     9061 ttgcggaaaa agtggataca agtaaatatc cagaaggtac aagttttacc ttcaaagaaa
     9121 ttaactatga caaagatggg aatatcaatg gaaaacacaa tgaagatttg aaagaaaaat
     9181 ctcaaacttt aacgcccaaa aaagttccga caacaccaag tacaccagaa caatctgaaa
     9241 tgccaactgt tccaagtggc tctcaagaat ctagtcctac agtgaaggca ttccctcaaa
     9301 ccggggagaa aacttccaat gtgctactgt tcattggctt tagcttgatc tttgcgacgg
     9361 ctggctatta tttttggaat cgtcggaact aaggtgataa gatgaaacat gtaaatagta
     9421 gaaaacaata cgcgcgaccg cctcctaaaa aagtggtcgc gctatttttg tattcaaaac
     9481 taacaatgaa aagaggaaaa aatatggaat tgaaatttgt tgtaccagat atggtcgaga
     9541 cgttcggaaa actaacatac ggtggtgaag gtgaagttct atcggaaggg tatggtcgaa
     9601 atactacaat tgttggtcga agttaccatc tgttttcaaa taaacaacgg gccgatgata
     9661 ttgaagtggt ggtagctgcg gaagccggcg aaaaggattt tgaccaagat caaccactaa
     9721 aagctgtaaa tccccactta attgccaaag gctatgaaat tgagaatcgt gggtttaccg
     9781 attacgtgtt gtatgttgat gatttagtga aagcatagga ggaaaagaag atgagattaa
     9841 cagaaggtat tgtcgtagat tcaggattaa cctttggcaa gttgcgtttt tccgcattac
     9901 gtcgagaagt acgcaagcaa aatgaggacg gaacggttag taacgaggta aaagaacgga
     9961 cctataattt gaaatcctcc gcgcaaggtc gaatgatcca agtcagtatt ccagcaaatg
    10021 tacccttacg cgagtttgct tatgatgcag aggtagagct ggtcaatcca atcgtggata
    10081 cggtcgccaa ttatgttttt cgggaaggaa ccaccgttaa ttggtttatc aaggcagatg
    10141 atttagtctt gaaacgacaa ctgaatcaag gaaaacctac gaaccaaaat gaaggaaaga
    10201 aataggtgaa gaatatggaa attaatgttg aacatatttt agattgtctc gatcaatttg
    10261 gcaaaggtga gctaacggag gaacaactca ctaacgcatt aacctatgat gaaaaaatgt
    10321 ttctgattat gcatcaaggg ttactggaag taggtaacga tgccaaagaa gactttgatg
    10381 tactggattg gttaggggaa gaagagtctt tctttatggt tgtcgaggta aatgaaagtt
    10441 tatgtcggca ggcagaatct gttttggaag aaatcgatgt ggagatgccg gatgccatcg
    10501 aaagattttt aaaacaatta gtggaaacga aacaacttcc cgtagtagta aatgactagc
    10561 ataacttttt gaaattgccc aatgaaatcc tattgggctt tttcgactgg aggtggaaac
    10621 catcaaaatg tacaaaggac atcgcatacg cgcaggagat caacacttga tttatcactt
    10681 tgttcttggc tggctaatct ttttgttcat tggttggatg agcgtctttt atttacaaga
    10741 acttagacaa tttgatattt ctaaggtatc attttccact agtgaaattg gctggtctat
    10801 gaaggatgta atctgcttgc taggaagtct cgctctttca ggaagcatga tgttacttta
    10861 tatacacttt tttcaggatc attggcgaag tctttggcat cgacaaaagt tagctcggat
    10921 gattctagaa aaccattggt atgaagtaaa gcagactcaa ggtgaaggtt ttttcaaaga
    10981 tttgaatagt agttggacca aagagagtat cagttacttc cccaaaattt attatcgaat
    11041 gaaagatggc ttactttcta ttcgcgttca aatttcactg ggaaaatatc aggatcagct
    11101 attgaagttg gaaaataagt tagaaagcgg actgtattgt gagttagtag aaaaagaact
    11161 caaagactcc tatgtggaat acaccttgtt atacgatatg attgccaatc gaattgggat
    11221 agaagaaata gtggcagaaa atggggcgtt gcgattgatg aaaaatcaag tatgggcgta
    11281 tgattccttg ccgcatatgt taattgctgg cggcacaggt ggtgggaaga cctatttctt
    11341 actcaccatt attcaagcac tattgaagtc agatgcagaa ttgtttatcc tcgatcccaa
    11401 aaatgcggac ctcgccgatt taggtacgat aatgcctcac gtatactccc aaaaagaaga
    11461 aatttctgaa tgtgtggaag atttttacga acgcatgata gctcgtagta ggtcaatgaa
    11521 agaaatgccc aactacaaaa caggagagaa ttatgcgtat ctcggacttc cgcccaactt
    11581 tttaatcttt gatgaatacg tggcttatat gggtgcgaat cgttttccta caagcatcga
    11641 atagatgtga aatggaagcc tattgagatt atcaatagtg acaactaatg ttttgagaga
    11701 tggaatgaaa gccttcaagt tgagctgaaa catccccgct aatactccta catgctctaa
    11761 tcaatgaagt agattggttt tggtatgaag ctaggtgaag tcgtctgaaa tctgcctaag
    11821 tgcttgagca taaggctgac tatagggcgg gcggctgaaa aagataacta tggtaagaat
    11881 gtctgaaaat gactgacgaa tctgcgaatg tacgggtcta aaaggctgat cttattgaaa
    11941 gataggaaca tacggacgta tggtgagata ccgacaagta aggttccatg atatgaaaat
    12001 cgggatagct aacgaagaag ctataatttc acaggctcat agtagatacc taaggttata
    12061 catgatagct aaaaacattg gaacgatgta agcagaaaac tatcaattaa atgactactt
    12121 ctagataggt gcatataagt aataacgaaa ttgctttgtt tctgtgaaag taagggcaca
    12181 gtaccgatga agcgtctaac aaatgtggag ggatagccct aagtctattt aataacaatg
    12241 aatgttgaaa cagatgaagt tcaaggatct ggtaagaacg tgggaaaatc cgttatggag
    12301 gtgccacgct tgaacacaaa aatacgttac tgggaatatt atgatctaca agaaacattc
    12361 gatcagctat ttactcaaag tagaaacggg aaaaagtttt atcaattata tgagttaatc
    12421 atttctgaaa ataatattct tttagcatac cgtactatca aggcaaacaa ggggtcttcg
    12481 acaccaggaa cggattcctt cacaattgat aactataagg aaatgaacca agcagagttt
    12541 atccatctta ttctcagtca tttagaaaat tacaaaccaa aatccataaa gcgagtaatg
    12601 atacctaaac ccaatggtga gaaacgccca ttaggaattc catgcatgat tgatcgaatg
    12661 atccaacaga tgttcaagca gatactggag ccaatatgtg aagctaagtt ttatgaacat
    12721 agctacggtt tcagaccatt gagaagtgca aagcatgctc taggtcgcat tatgtatctc
    12781 ataaacatca gtaaaatgca ctatgcagta gacattgata tcaaaggttt ctttgataat
    12841 gtaaaccacc gtttactgat aaaacaatta tggaatatag gaatttgtga caaacaagtc
    12901 ttagctattc tttcaaaatc tctgaaatca cccattcaag gagaaggtat cccgagcaaa
    12961 ggaacgatcc aaggaggtat catttctcca ctattatcta atgttgttct aaacgactta
    13021 gaccattggg tctcaaagca gtggcatacc tttgaaacaa agtatcccta tactaaaggt
    13081 tacaataaat ttcgtgctct aagagataca aatctaaagc aaggctatat tgtcaggtac
    13141 gcagatgact ttaaaatcat gactaatgat tatccgacag cattaaaatg gttccacgct
    13201 gtcaagcttt acctaaaaga cagacttaaa ttagatattt ccaatgagaa gtctaaaatc
    13261 gtcaatttgc gtaaatgtaa gtcggaattt ttaggattcg ctatttgcgt gaaacaaaaa
    13321 gggaaaaaat gggtttgtaa ttcacgtatt tctaacaaaa aaaaggatca gattaaagaa
    13381 gagattaaac aaagaatcaa agatattcaa aagagtccta cagcacaaaa tgctctcctg
    13441 tttaatgctc tcgtgctcgg tgttcataat tatttcaggt atgccactca tattaattta
    13501 gatttgaata ggatgaacta cgttctttca ttcactactt acaaccgatt atcaaattgt
    13561 agtacaagat gttaccccaa caaagcttcc ccaacttaca aaaagtttta ctcaacaacg
    13621 atgaaaacgt ataaagtagc tggagtctat ttgtaccctc tttgcgacgt atctacaaaa
    13681 acaatttacg gatttaatac ggaggataca ccgtttactc cgtttggtcg tcaaagattg
    13741 gagcacaaaa gcctacagtc tcttgtgttc caagaattaa gaaaattgat ggaatcgaaa
    13801 ataccgaata gaacggttga gtatttagat agtagaatat ctcgttactc aatgaaatca
    13861 ggcaagtgtg agattacaaa acaatttttg ccagcaaaag ccgttcactg tcatcactat
    13921 ttgccaaaaa gtcttggtgg agacgacaaa ttcgataact tgagaattat tcataaggat
    13981 atccatcttc tgatccatac aacaaataaa atgataatcg atcactacgt gcatgaactg
    14041 aaactggtgc cagagcaaat agcaaaaatc aacctttatc gaaagatgtg taatctgcaa
    14101 aacattcaat agaaaataaa tagatggaac gccgtatgag gtgaaagtct cacgtacggt
    14161 gtggagcggg ggaaaagatg gagattatat caaattctta cctatcgcta tagatgttaa
    14221 cgacaaaaga aagtgcggtg attttgaata agcttaaaca aatcgtgatg ttaggccgtc
    14281 aatctggttt ctttctgatt ctagcttgtc aaaggccgga tgcgaaatat ctaggagatg
    14341 ggattcgcga tcagtttaac ttccgtgtgg ctttgggtcg tatgagtgag cttgggtatt
    14401 ccatgatgtt tggagaagtc gataaaaatt tttttatgaa acgcatcaaa ggacgaggtt
    14461 atgtagatac agggggcagt gtgattagtg agttttatac gccacttgta ccaaaagggt
    14521 atgatttctt aagggaaatt agcaacattg ttggattaac cgttcatacg gaaagagaaa
    14581 ataatagtgt gtagcctagg aatatcaata atcctgggct tttttattga ggtgatttat
    14641 gacattttta gatttattcg ccgggattgg tggctttcgc ttaggtatgg aacaagccgg
    14701 tcaccagtgt atcggttttt gtgaaattga tgaatttgct cggaggagtt ataaagcaat
    14761 ccatgataca aggaaggagg tggaaatgca tgacatcaca agtgtatcag acgaatttgt
    14821 tcgatccctc ggaccagtgg acatcctttg cggcggcttt ccgtgccaag ctttttcaat
    14881 tgcgggaaag cggcaaggat tttccgatac tcgaggtact ttattctttg aaatcgctcg
    14941 gttcgccact cttctccaac ctaagtttct attccttgag aacgtccggg gattgctcaa
    15001 tcacgaagga ggggctacgt tcgagacgat cctccgaacg ttggatggat tggggtatga
    15061 tgtggaatgg caagtgctta actcaaaggc ctacgttccc caaagccgtg agcggatctt
    15121 ccttatcgga cattctcgag atgcatgtac cgaacaagta tttcctatca ttggatcgtc
    15181 ttcaacatct gatcaaaaca tcagaaactt ggtaaatatc aatccttcca atcgaggaat
    15241 gggtggccaa gtctatggtt cagatagcgt agcaccaacc ttgaccggtg atgaaggaat
    15301 taaaattgcc ttaccggtaa aggatgggat ttctgtagcg ggtatgttgt cgggaaattt
    15361 tgaacaaggc aataggattt atgaggtaac cggaacagcc cccactttgt caacgaaaca
    15421 agggggaacg aagattatga ttcggaaaaa tgaaacagaa tatcaagagg tgaagccagg
    15481 ggacagtgtg aacctggctt ttcctaattc cacaagtcgc cgaggtcgtc tgggaaaaca
    15541 aagtgtgcat accttactaa caggagacca acaagcggta gtcacggatc agtaccagat
    15601 tcgaaagtta acacctaggg agtgctggcg gcttcagggc tttccagatt gggcttttga
    15661 tcgagcttct caagtcaatt cagatagtca gttgtataaa caggccggaa actcagtaac
    15721 agttccggtc atttttgata ttgctagaag attaaagggg gtaaaagcat atgatttatg
    15781 acgagttgat tggagaaatc tactggatga ttggcaagat tcaggcagat ccgaaattgg
    15841 aagaagaact gtaccggctc aattttgata ttcgcaaaaa cggggtgaaa gtccaggtga
    15901 ttcgtatgta gtggatgagg aaacggatgc tcgaatggag ctcaatcaag tcatcggtga
    15961 attggaacga attgcggacc ttgccaaaga acctgatatc cgccaatact tgtttgagat
    16021 aaaagcagag ttggaaattg agggtatcac cgcggagtaa tagggaaata acccactgat
    16081 aggcactgac cgcgggggat ttgcgaagca gaaatcctcc gtggtgctgt gcctgttcat
    16141 ggacggcggc agccggccat gatgtctcac cccccgtatc taacaggggg gtacaaaaac
    16201 acaaaaaaca agcaagtaac cataaaaaat gcttgttgta tcaaggatat taagtaattt
    16261 gtataggtgt taactcattt ggaaaagtta acaccttgaa tttggaggtg aaaacttggc
    16321 gcaacgaaat ttagattatc ggttattaaa agaacgacgc aacgaatatg gcgtttcaca
    16381 aaataaatta gctactgctt gcggacttag ccgcccatac ctaaatcaga tagaaaacgg
    16441 tggcgtaatc gcctctacaa agaccatgag aaaaattttt gatcaactgg aaagtttcaa
    16501 tcccgattta cctttaacgt tactatttga ctatgtaagg attcgctttc ccacaacgga
    16561 tgtgcggaaa attattcaag aaattctcca tttgaaattc gagtatatgc ttcatgaaga
    16621 ttacgccttt tactcctatc aagaacaata tgtcatgggc gatattgtag tgatgttatc
    16681 tcatgaagaa gataaaggtg tccttttgga attaaaaggt cgtggttgcc ggcagtttga
    16741 aactttttta ctcgcccaaa agcgtagctg gtacgacttt tttgaagatt gtctaaaagc
    16801 cggtggcgtg atgaaacgct tggatttagc aatcaatgat cgagtggggc tactggatat
    16861 tcctgattta acgaaaaaat gtcagaagga agaatgtatc tccttgtttc gtaccttcaa
    16921 aagttaccgt tccggggaac tgttgaaagc tgatgaaaag gatggtatgg gcaatacctt
    16981 atatattggc agcctcaaaa gcgaggttta tttttgtttg tacgaaaaag attatgaaca
    17041 atatatcaag ttagggattc cattggacca gaccgaaacg aaaaatcgtt ttgagattcg
    17101 gttgaaaaat gaccgtgctt attatgcgat tcaagatttg ttaaaaggtc gtagcattga
    17161 aagtaccacg ttttccatta tcaatcggta tttgcgattt gcggataaag tagatggaaa
    17221 acggcgaacc aattggccct tgaatgaaca atggggtcgt tttattggac ggaatcggaa
    17281 agagattcaa ttaacttctg aaccgaaacc gtataccatt gaacgaacat taaattggct
    17341 aggtagacaa gtcgccccta cgtggaaaat ggctaaggag ttggatcgat tgaatcaaac
    17401 aacgtatatc caggatatgg tacagaatgc gcgactctcg gaccggcata aaaagatttt
    17461 ggagcaacaa agtatggcaa tcgaaaactt gattgtatga aaagaggaat tttgatggaa
    17521 attgtaaaag atatgttatt ggtacttggt ggcagtatgc ttggtgttac cgtgatgtgc
    17581 ttgatgaatg caagtgcagc agcggattga gcaatggaaa agaaaggaaa gtgacaaaat
    17641 gaatttcgga caaaatttat gtgcgactcg ttccttagtg aaaagctaag gcactaataa
    17701 aagaacgaaa aagtttggtt attaggagaa ctgataatct gacaggtgga atgatgaagt
    17761 aacgctctga aacgcctgcc ctgagcctcc gacaagcatt gtatgaggaa actcagaatg
    17821 tttgaagctc ggtaaagacg gctgaaagat accgtaatag ttgatgaaca tatatcttct
    17881 atcgaaaact atccagaggt gggtagcgta tccaacaggt cgggggtcta taaaatatct
    17941 atggttagaa tgttctataa ggaactgacg aaacagcgaa tgtacgggtc taaatttgaa
    18001 ctttgtagaa atgcaaaggt acgagaaatc gtagctggtg tggcaaagta agaatatagg
    18061 ttatgaaatg ccatataacg ttacaggcgg tatcaagcca gcaggcttat agctagtgac
    18121 ctaaggatat atatgtatag ataagattat cggaacgagg aaaggtattg ggttctcatc
    18181 aagagaataa actgacgaag aacaataagc agttgaacta atgctgaaaa gcagagggcg
    18241 aacctaagaa attcttgtaa tgagaatgga ggaatgccct caagtcgtgt atatattaga
    18301 aaagtattat gttgtttcaa taaggattac gagtaagata aaaaagctca ctcaatttca
    18361 agtaaaggag tgaagcctta tgcctaaaaa taaaaatgaa acattgtgtg tagaagattt
    18421 aagacacgct gaatattacg aaatgcaaaa cacctttgat gatttatatg ccaaaagtaa
    18481 gaatggagat attttcactc atcttatgga tattatccta tcgagagaaa atatattact
    18541 ggcatatcga aatatcaaag caaatgcagg cagtaaaaca gcaggaacag acggtacaat
    18601 aattaaagat attggcaaat tgccagcaga aacagttgtc aaaaaagtaa gatacattgt
    18661 tgcaggcagt ccacatgggt atcgacctaa gccagtgagg cgaaaagaaa taccaaaacc
    18721 aaatggtaaa accagacctc taggtattcc ttgtatgtgg gacaggctta tacaacaatg
    18781 tataaaacaa gtattagaac caatctgcga agctaaattt agtgaaaaca gctatggttt
    18841 tagacctaat aggtcagttg aaaatgcaat aaaagcaacc tataaccgcc tacaaatcag
    18901 ccagctacat tatgtgattg aatttgatat taagggtttc tttgacaacg tgaaccattc
    18961 caagctgata aaacagatat gggctatggg aatacgggac aagcacttga tattcatttt
    19021 aaaaaggata ttaaaagctc caatcaaaat gactaacggt acaataacat atccagagaa
    19081 aggaactccg caagggggaa taatatcccc actactagca aacattgttc ttaatgagtt
    19141 agaccattgg gtagaaagcc aatggcagga aaatcctgtt acaaaaaact atgtggttca
    19201 tatcaataaa agcggtagcc catgtaaaag caacgcttac aaagaaatga agaaaacaaa
    19261 gttaaaggaa atgtatatgg ttcgttatgc agatgatttt agagttttct gccgctacaa
    19321 ggaaagtgct gaaaaagcca aaatagcaat cactcaatgg attgaacaac gattaaaatt
    19381 ggaagtatca caagaaaaaa caagaattgt aaatgttaga aaaagatact ccgactttct
    19441 tggtttcaag attaaaatga taccgagaag aaagaagtta gttgttaaat cacatataag
    19501 tgataaacaa ttcaaaaacc aaaaagacaa gctggtatca caggcaaaga aaattgcttc
    19561 tccctcaaaa gggaaaacgg aattagaaga aacaagactt tataattcaa tggtattagg
    19621 tatgcaaaat tattatcaga ttgcaacgaa tgtaaatctg gattgtatga aactgaatag
    19681 agctgtaatg gctatcttca ctaacagatt aggtacaaac aaaaggggca gattgagaaa
    19741 aacaggcaga caacttacga caaaggaggc aacaagatat ggtaaatcta aaatgcttcg
    19801 gtatgttgct ggcgagggcg aacctatttt ccctgttgga tatatccaac acagaaaacc
    19861 aatggcaaag gtgtatttag cgaattgcta cactctagag ggaagaaaat ttatccacac
    19921 caatctaagt gttgataaat tactgatgta ccagttaatg aaattatctt tggaaaatcg
    19981 cacaatagaa tacgcagaca atcgaatttc gctattttct gctcaacatg gaaaatgtgc
    20041 tataactctg gaagaatttc aacaagctaa tgaaatacat tgtcatcata ttgtaccaac
    20101 tggagctggt ggaaatgacg attataaaaa tcttattttg gtaaaagagg cggtacaccg
    20161 tctaatacac gctaaaacag aagaaacaat acaaaaatat atagctctat tgaagctaaa
    20221 taaagtccag ctcataagac taaataaata tagagtatta gctggcaatc aagaattaaa
    20281 cttgatatag gtctactaca taaatacttt tcaatataaa cacgatggaa cgcggagtgc
    20341 ggtgaaagtc gcacgctccg tgtgaatggg gggaaaagtt tgagatattt ataatatcag
    20401 gaacttacct atccatatat caatggtttt taaccaatgc tcaatcttta gtcttactag
    20461 cgattgtggt cattggtttg tttttaggat ttaaacggga gttttccaaa ctgattggct
    20521 tcttggtgat tgctttgatt gcggtaggtc tggtctttaa tgcttctggt gtgaaggatg
    20581 tcctactcaa tttgtttaac cgaattgtcg gtgcctgagg gggaatcaca atggaacaga
    20641 tgcgtgttta tattgcgaac cttggaaaat acaatgaagg tgagttggtg ggggcatggt
    20701 ttaccccacc tgtcgatttt gatgaagtga aagaacagat tggattaaat gacgaatatg
    20761 aagagtacgc gattcatgat tatgaactgc cttttgagat tgatgagtat acgccaattg
    20821 aagagattaa tcggttgtgt aacttagcgg aggaactaga aggaacgcca attggtgaag
    20881 ctgcttctga gattcaacac gctttcttca attctttcga ggaaatggta gagcatgtgg
    20941 atgatattgt ctattatcca gattgcgatg atatgagtga tgtggcgcat tacttgattg
    21001 tagaagctgg tgattttggc gaagttccag aacaattgaa gccgtatatt gattttgatg
    21061 cttgcggtcg agatttggag attggaggaa attatttggt tactagtcgt ggagtttttg
    21121 agtatccaga atgaatcaaa cactatatat agtgtttgat tagtatatgt aagcaaaaaa
    21181 acacaatata tagagtgcaa actgaagggt aatgtgatat aatatttgcc gaagaaatat
    21241 ttttgaaatg aggtaatatt atggcaaata ttcaaacaag ttttattgat ttccataatt
    21301 caattagatt ggacgtagaa gacaatacgc tacttaagga ctataaagac caagtaattg
    21361 atggattaaa agattactta cctgatgatg tgaagtttga aactttttta cagggaagct
    21421 attctgttta taccggaata aaaagctgtg atgaaaaaat tgattttgac atcgatattg
    21481 cagttgcttt cgaaattgat catactgttt atgaagatcc aagggagcct aaactgtggg
    21541 taaaagaggc gctagttgaa atttttccta atgctcaagt taatttaaaa gtaccttgtg
    21601 taactgctac atttactgga aaaaagacaa aaaaaaatgt gcacgttgat gttgcggttt
    21661 atgctaaaga agatgaaaat tatttcttag caaaagcaaa agaattcagt gctcccgaaa
    21721 accgatgctg ggaggaagcg gatcccaaag tattaaaaga gaaaattaat agtcatgtag
    21781 cagattcaga tgatcgaaaa caatttcgaa gatgtattcg ctatttaaaa agatggaaag
    21841 ataacaattt taaccaagaa tataaaccaa caggaattgg acttacaatt aatgtgatgg
    21901 atacgttcct agttaataag tccactgatt ttttaactag aaaagttcag tataatgata
    21961 tggaatgtat gaagcagatt gtttcttcgc tgaaagattc atttgtgtat gagtacagtg
    22021 aaacagatgg ttggcattat cgtctacatg catatcttcc agtgaagcct aacagtgaca
    22081 cctattcaaa aatgacagtg aatcagatga gtgattttaa aaacaaactt tctaaattat
    22141 atgatgattt gattttcgct atcgatactg aagatgagta tgaagctaca aaacgattaa
    22201 ataatcaatt tggggaggat tttttaatta tttcagaaga agaagttaca gaaaaaaact
    22261 taagaaatgc atttgttaca gactatccga gtgcttaggt tggtgttaaa gattggatta
    22321 tactgatatt ttaaaagaaa agctaacaga tgttgtgcgt ttattcgatg gtaattacta
    22381 tggggatttt tcatttgcta caattggaaa gttgcgttta aaaattgaaa taccaaaaca
    22441 ttttccattg gtacttccta ggatttacat tcataatttt gatcatttag gactttacct
    22501 accacatgta gaaaaagatg ggttggtatg tttttcttca gatataaatt atttagtaga
    22561 tgaagaaaat tcagaattgg ttttattgca gtgtgttaat aaaactataa aaacaattga
    22621 ggaaggtttg aaagggttaa ataaaaatga ttttcgaaaa gagtttgttg ctttttggga
    22681 caaacaagag aatcaaattt cgttattcta cctttgtgaa ccagcgttgt ttatcaagtc
    22741 agttgataca ataatgtacg gtaagtcttt ggttgctttg gataaagaga acgaattaca
    22801 attaaatgca gcgagtagat tgtttaatgg agagaaagaa gatactcatg aattagatgc
    22861 atactatgtt ccaattagaa acaagaataa tattatgccc ccgaagaata ataaagcatg
    22921 gtcaaagaag gatattttac aaatagtaaa aaaaaatgta acaggtgcaa ataaaagatt
    22981 ttttttaaaa cttgaaaaaa gaaagaatag acataatgtt ttacttattc tagatatccc
    23041 aattgaagaa aagtcaaata atgtcataat tggatttctt tttacaaaac aatctggatc
    23101 tataaaagat tataagggta cgcctaggac tgtattagtt cagcgtcatg atgaattata
    23161 tttggtgaat agaacgagcg gagaaaacta tggattgggt gctaatatag ctattgttgg
    23221 ggtagggtca gttggcagta aaattgctga aaatcttggt ccattaggtg tgagaaagat
    23281 gacactcata gacaatgatt gttttcaagc tgaaaatttg tatcgaaatt cacttggtgc
    23341 agatagttta aaaaatgccc gatctcagaa taattttttt aaagttgatt taatgcagga
    23401 ggagctcgaa aaaaaaatcc catacctttg tgttgaagtg gagtcaatga acgttttaga
    23461 cttaattagt atgcaacctg gttttttcaa ggaatatgac tatgtttttg tttgcatagg
    23521 agatacaatg gcaagcctgg ctttaaataa ttatttttcc aaaagtagtc aaaaagtttt
    23581 ctattcttgg ctggagccat atggcattgg gggacacact ctatttataa attattctct
    23641 aaatcaaaaa ggttgtttca attgtcttta tacagattca aactctaaaa ataggtgttc
    23701 aaatagagct tctctggtaa aagaaggaca aatttttgaa aggactttag cgagttgccg
    23761 ctcaaaattt ataccatata atgctattgc ctcgacggaa tgtgcaatta atgcaataaa
    23821 acttttccat aaagtcaatc aaaataatat gaccaatagt actctttttt catggatagg
    23881 agatgggagt acttttgaga atttaggata tcaatatagc gacagaaata cttttcttaa
    23941 tggagtcaat aagtttgaag aaagattctt ttctaaatat tgcaaagtat gtggggagtt
    24001 agatgattaa attttcgtgt gaccgtattg tcattgaagt aagggatgaa gttcttaaga
    24061 tatttgaaca atatcggcag ggaaaggatg acttgcctga agctggagga gttcttcatg
    24121 gaaaaagact taagaatggg agcataataa ttaccgatat aacaacacct caaataggag
    24181 atatacaaaa aagattactc tttaaaaaaa accgagaaat tcatcaacag ctttctaatg
    24241 agaaatggat agaatcaaat aagttttcta ttgcattggg agaatggcat actcatcctg
    24301 aagctgtacc aactccatca aatgttgata agaaaagctg gagactgaac gtgagcaagc
    24361 aacatgatga tagagtttat gtttttatta tcgttggatt ttctgatttg agaatgtggt
    24421 tactgtcaaa aaaatcagat attaggcagg ctataaaact ataaaggagt gattaggtga
    24481 aatcacaaaa gaatatttgg tggtgggggt ttttagtagg aaaggtaatg ataccagccc
    24541 ttctcttaat ttctctaccg atgattactt ttttctttac caataaaaaa atgagtaaag
    24601 aagccgtgat ttttttcttt ggagaccaaa aagctacctt tattgaaacg ttagtaacat
    24661 ctcttcagct taatttgaat tacatttttt caattattat tgttatatcg ttattgaatt
    24721 tttttaaaaa aagaaattca ggaaaggtgt ttaactctaa tggaaatgtg tactacaact
    24781 atttttattt tgtattttgg gtagcagcaa ctttacttgg ttatgataaa attcagattg
    24841 caggaattcc tatacacatg caatataagt tggttttgag tggaattttt tctgaggtgt
    24901 tgccagatat atacgatgat cattacgaca gtgatggaac atgtaaagta agcattgaaa
    24961 aagaaaattt cgatgacatc gatggatatg actctgtgaa cttactgatt attgatactt
    25021 acgatataaa aatgagtgaa ttatctatgg aaaatcaaac atatcctacg ataattgtta
    25081 gagggaattc aatagatgga gttcgtaaag ttaatagatc tttaatcttg gaaataaaaa
    25141 aaacaatgga tgaaattcaa aaaagtgact ttaaaaaagt atttgttgct tcaacatcta
    25201 atccaaaaaa tagtatcaat attattaatt catcgtttag atttttcggt cgatcacgta
    25261 ggtttaaact ttatgttctt caaaaggatt atgcaagcaa tggaaagtat agtaagaaat
    25321 atagaatttt tatttaagaa ggaatttttc cttcttttta ttttggagga aactatgaaa
    25381 aaaataaaaa gctacaccag tatttgggca gttgaaaaag tcatttatgc gattaatgac
    25441 tttcagctgc cttttcctgt gacctttaac cagatggctt ggtttgtttt atccttgatg
    25501 tttgtcattg tatttgccca tgtgcctccg ctatccatga tagagggggc ttttttaaaa
    25561 tacttgggca ttccgatagc ggtcacttgg ttcatgtcgc aaaagacctt tgacggtaag
    25621 aaaccattgg gatttttacg atcctttatc agctatcact tacggtttaa ggtcactttt
    25681 gcaggaaaga aagttaaaga acagaagaaa cgatgggacg aaccaatcac cttggtaagg
    25741 agtgtgaatt atgtacccga ttaagtatat tgaaaataat cttgtcttta accaagaagg
    25801 cgagtgtttt gcttactatg aattagtgcc ttacaattac tcctttttgt cacctgaaca
    25861 gaagtatcaa gtacatgata actttcgcca attaattgcg caaaatcgtg aaggtaagat
    25921 ccatgcctta caaattgcca cagaaagtag tattcgtgcc acacaagaac gttcgaaaaa
    25981 ggaaattacc ggtagactca aagaagtagc aaagcaacga attgatttac agacagatgc
    26041 attagtatcc atgattggcg atagtcagat tgattatcgc ttctttattg gctttaaact
    26101 gatttcgaca gatgaagagg tcaatctaaa gaatctcagg aaatctttct tttctggact
    26161 tcaagaattt gtctatggag tgaatcatca tttgatgggt gattttgttt ccttatccaa
    26221 tgaagaaatt cgtcgctata ccaagcttga aaaactaatg gaaagtaaat tggctcgaag
    26281 atttaaagtc aaacgagtaa cgccgagtga cttgacgtat ttaattgaac atatctatgg
    26341 tgaaaaaggc acaccgtttg aagaatatga attccagcta ccaaagaaaa agctgaaatc
    26401 agaaacgctg gtgaaacgtt acgacttatt acgtcccact cgttgtttga ttgaagaaaa
    26461 gcctcggtac ttacggatgg aacatgaaaa tcatgagtct tatgtagcgt acttaacaat
    26521 taataccatt gtaggggaaa tggagtttcc ttcctcggaa cttttctatt accagcaaca
    26581 acaatttacg tttccgattg atacttcaat gaatgtggaa attgtgacga ataaaaaggc
    26641 cctagctacc gttcgtaata agaaaaagga attaaaagat ttagacaacc atgcctatca
    26701 atctgataat gaaacgaact ccaatgtatt agatgctttg gattccgtgg atgaattgga
    26761 aaccaccttg gatcagtcga aagaatccat gtataaacta agctatgtgg ttcgagtgag
    26821 tgctaaatca gtggatgaat taaaacgccg ctgtgatgaa gtgctcgatt tttatgacga
    26881 taccaatgta aaactagtcc ggccctttgg cgatatgatg ggtctacaca aagaattctt
    26941 accctcaagt aagcgataca tgaatgacta tattcaatat gttacgtctg actttttggc
    27001 gggacttggt tttggggcta ctcaaatgct aggagaatta gaaggcattt actttggcta
    27061 taacgtagat acggggcgca atgtttacct gaaaccggca ttggcatcac aaggggtcaa
    27121 aggctcagta accaatgctt tggcatctgc tttccttggt tcgttaggtg gggggaaatc
    27181 ttttagcaac aatctcttag tctattatgc cgtccttttt ggtgggcaag ctgtgattgt
    27241 cgatccaaaa ggagaaagag gcggttggaa agaaacgttg ccagaaattg cggatgaaat
    27301 taatattctt aacttgacca gtaagccaga aaatcaaggc ttacttgatc cctatgtgat
    27361 tatgaagaaa aagaaagact cagaaagttt ggcgattgat atcctgacct ttttaacagg
    27421 gatttccagt cgggatgggg agaagttccc tgtgttacgc aaagccattc gaacggttac
    27481 ccaaagtgat cagcgaggat tattacaagt aatcgttgaa ttgcgtaaag aggactcacc
    27541 agtcgcggaa aatatcgcgg atcacatcga gtcctttacc gattatgatt ttgcccattt
    27601 gcttttctca gatggttcga ttacccagtc gattagttta gataagcagt taaatatcat
    27661 tcaagtagcg gatttggttt taccagatgc agaaaccact tttgaagaat ataccaccat
    27721 ggaattgctg agtgtttcca tgctaattgt tatttccact tttgccttgg actttatcca
    27781 tagcaaccga gaaattttca agattgtgga cctggatgag gcttggagtt ttcttcaagt
    27841 agctcaagga aaaacgttat cgaataaatt agtgcgtgct ggtcgggcca tgaatgccgg
    27901 tgtttacttc gtcacgcaaa acagtgatga cttgttggat gaacgtttga agaataatat
    27961 tgggctaaag tttgcatttc gcagtaccga tattcatgaa atcaagaaaa ccttggaatt
    28021 ctttggatta gataaagaag atgaaagtaa tcaaaaatgc atgcgagatt tggaaaatgg
    28081 gcaatgcttg atgcaggatt tgtatggtcg agtaggtgtg gtccaagttc atccagtctt
    28141 tgaagaactt ttccatgctt ttgatacccg tccgccagtt caagagagaa tggagtgagg
    28201 agatgaaaaa gaaacttttt cgtatctttg gaattgtttt aatcagtttg gtcactctga
    28261 taatactttt gagcttagtt ggaacggtag ctgaggcaac aggtctggtt gatgatacag
    28321 ttggagccgg aaatctttat tcccaatatt cacttggtaa ctatcagttg gatttctttg
    28381 tggatagttc gtgggattgg ctgccttgga attggggtga tggcctaggg aagagcgtaa
    28441 tgtatggact ttatgccatt actaatttta tttggacagt tagtctctac ttatcaaatg
    28501 ccacgggcta cgtggttcaa gaagcctata agctggattt catttcagat acggctgaaa
    28561 gtattgggaa gaatatccaa accttagccg gcattaccga aaatggactc cagacctcgg
    28621 gcttttactt tgggtttcta ttattgatga ttttagctct aggagtttat gtggcgtata
    28681 caggattatt aaaacgagaa actaccaaag cagtccgggc tgtcattaat tttgtgatga
    28741 tttttctact ttcgggttcg ttcattgcgt atgcgcccac ctatatcaca aaaatcaatg
    28801 attttagctc agatgtcagc gaagcggctc ttagccttgg aaccgagatt gtcgtgccga
    28861 attcagaaag ccaaggaaag gacagtgtgg atttaatccg agatagcttg ttttccattc
    28921 aagtccaaca accgtggtta ctcttgcaat ttgatgattc caatatagaa gaagttggcg
    28981 aagatcgtgt taacaaaatc ctgtctgtaa gtccagatga aaataaaggc aaggatcggg
    29041 aagaagcggt caaagcggag attgaagata atgacaatgc gaatctcagt attaccaaga
    29101 ccatgaaccg cttagggacc gtggtctttt tggtgttgtt caatattggc atatccttct
    29161 ttgtctttct cctaacaggg attatgttgt tctcgcaaat tctctttatt atctttgcga
    29221 tgtttttgcc gattagtttc ttattgtcca tgttgccgac ttatgagagt ttgggcaaga
    29281 aggcgattat tcgcttgttc aatacgatta tgatgcgagc aggagttact ttggtgatta
    29341 cgactgcatt tagcatctcc acgatgtttt tcaatatttc ggcaacctat ccatttttca
    29401 tggttgcttt tctgcaaatt gtgacctttg ccggtatcta tttcaaattg ggcgacatta
    29461 tgaatatgtt caatctccag agtaatgata gccaatcaat gggaagacgg gtcatgcgaa
    29521 aaccgcaaat gttaatgaat cgaacattgc ggcaactcaa tcgaaatgtg ggacggactt
    29581 tggcttttgg tggtggtgca gcagttggaa ataagttggc aaaggaacaa tcaaaatcca
    29641 aatttaagcc atccggttct tctctacgaa agaattcacg attaccgaac gatcacgaga
    29701 taccatctga cttgaataag gaaaagccaa ttccaaataa taagaaacaa tcccgaatga
    29761 atttggccgg gagaaaagtc ggcaaggttc tggataccca agctttggtg aaagataaga
    29821 ccaaacaagt aaaggatgga gtacggaata cgccaaccaa cttgaaatac aacttccata
    29881 aaggaattga aaaaacgaaa aaagcaccgg aagagtttaa gcgaggactg gtccaagaaa
    29941 aagcaaatcg aggagagttg cgagaaaaac aacaacaacg tagagacgaa aaaatagctg
    30001 aaaagcgcaa agtattgaac gaaataggga atcctcatgg gaaaagaagg gaaaatgttc
    30061 cgataaaagc aaaggtccaa tctcaaaagg atagagcacc aaagcggatt gtgagagcaa
    30121 attcgaatcc cgaaatcaaa cgaaaattcg ctagccaaga aatcatttca aaaggaataa
    30181 accaatcctc aagtaagaaa aattcttttc aacaagtgaa acggcggtct actctgtcca
    30241 aacgaaccaa tcgaaaagta caaaaaagtt tgaaccctca tcccaaacca aggtcaggtg
    30301 agaaaaaatg aacgtaaaga aattaagtgc catttcgtta actttcctaa caatctcttt
    30361 tatgggtatc ttgatgtgtg tgggcttatt gtttggtgaa gacagtgaag gaagtagtag
    30421 ttcaggtgct cctcctgggg ggagtagtgt ctcagaagag gttttgaaac accgtgcaat
    30481 ggtggaaaaa tatgccaaag aatcggatat aacagagtat gttccgattc ttttagcgat
    30541 tattcaagtg gaatctggtg gcacaatgga agatgtgatg caaagttctg agtcagccgg
    30601 tttaccaccg aattcattaa gtaccgaggc atccatcaaa caaggatgtc tctattttgc
    30661 gtctttggtt aagcgttcca aagaattagg ttgtgatcaa gatagtatca ttcaggccta
    30721 taactttggc ggtggttatt tggactatgt ggcaaaaaac gggaagaagc atagttttgc
    30781 tttagctgaa tctttttcaa aggaaaaatc ttgcggtcaa aaaatcgatt accctaatcc
    30841 catcgcgaat aaggaaaatg gtggatggcg ctataactat ggcaatatgt tttattgctt
    30901 attggtgaag caatacctaa ctacaacaca gtttgacgat aaaacagtcc aagggatttt
    30961 tgacgaggcg tttaagtatg aaggaacggc ttatgtattt ggtgggtcaa gacccgaaac
    31021 aggatttgat tgtagtggct tgactcaatg gtgttatgcc aaagttggtc tgaaacttcc
    31081 tcgggtggct caagatcagt atgatgccat gacccatatt gacctaaaag atgccaaacc
    31141 aggggatttg gttttctttc attcgactta tgatgccggt acttatgtga cccatgtcgg
    31201 tatttatgca ggggagaatc gcatgtttca tgcaggagat ccagtaggct ggacgaatct
    31261 aacagaaagc tattggcagc agcatcttat cggtgctgga cggtacaaat aagagaaaag
    31321 aggaaaaaga atgaagataa aaattgaacg gaatcaaaag gaaaagagcc taaaaaagaa
    31381 aaaagaacga gtcgtatccg tgggtaagca tcgaaaaatg gtgcttgccc tttggctttt
    31441 attatcttgt agtcttactt ttggcgttta taaaaatttc accgccattg atcaacatac
    31501 aactcatgaa aaagtggtta ttaaagagaa agtagtgaat acttctggta ttgaaaactt
    31561 tacgaaggat ttttcgaaag aatatttttc gtggaaaaat aacaaagaag caattgaaaa
    31621 gagaatgaac aacctcgaac agtaccttac agaagaaggt ttcgctttaa gtcaagatat
    31681 ggttcgagca gatattccca ctaattccga agttcagtca gtaaaagtct tagatgttga
    31741 aaagagctcg gaggaatttg tcgtttcatt tttagtggag caaaagatta cagagggaaa
    31801 aaaggcacaa tcgatttctt ctgcataccg agtgacgatc tttgaagatg aaaacaggaa
    31861 ttatatagta acgagtttgc caactatgat tgcaaaacct gatagggcaa aatacaagac
    31921 aaaacaagta gaaaatgatt cgaaaattga tgccaaaact acagaagaaa tcgctgagtt
    31981 tttggaaacg ttctttaaat tatatccatc agcttctgaa aaagaattgg agtattatgt
    32041 tgaaaatgat gcgatgcgac caatcaatat tgacttaaag ttttcgaagt tagaggatcc
    32101 agtttaccta caaaacggaa aaaaaattct agtgagtaca aagataaaat accttgataa
    32161 tgtatcaaaa accactagct actttcagta caaattaata ttacaaaaaa atggaaactg
    32221 gaaaatcatt gatgttaaat aataatgact caatctaaat ttatgagaag ttataagtag
    32281 tttaacttat ttcaggcaga agtcgcccat cctctatagg tgggtgatga atgccgttcg
    32341 gtaactcgaa aaccgacaat taagacatag tgccttttta ttttaatcca tgtcataatc
    32401 agtctatata agaaatggtt gatataccat ggaattagat acaaataatc attcattatt
    32461 tcttctttgt taccacctta ttttagtagt gaaacattgt aaacatctca ttgatgatgt
    32521 aatgttagct tatgcaaaaa actatctttg aaagaatatc agaatcacat cacattacct
    32581 tagttgagtg aaatcgtgat aaagactact ttcatattat gctcaaagca caacctaaaa
    32641 ccgaattaac aaaattcagc aatgcctaag ctcatgtctg ataaaatgag actttctaag
    32701 ggtcaaaaat ttcctttgaa tacgatcatt agcttagata aaagtaaaaa ccttagaact
    32761 acggggatag cttggttaat aagagatatc gctgttaata aagacataag cttgcaagta
    32821 tgctctattc ccaagaatct cccacttcaa gcactaagga tcgttaaatt cagctaagtg
    32881 gcaagtagtt cactagacga taattatctc catatttcaa tctcagcttt tccatttttc
    32941 atagcaaatt ccgttatttt tatagcatct aaaagattca gcttttccac tgatctttca
    33001 ccacttttca gcttttttat tgtgcttaaa ttgataccag taccttttga tattgaattg
    33061 gaagtaaaat cattaagggt tttttttatt aaattcatat ccgcaattcc agcgttcata
    33121 agaatgaaga ttctcctctc atagactact ttgaaaatgg tactacagtg gctgtttata
    33181 tatttcagta ggttactgta gtggtcattt tattataatt agaaaaggaa cctaaatcaa
    33241 aaatgctaaa gaaaattttc atagtattaa acctatcatg actaaagcca cggaattctt
    33301 gataaaagag tatacttgca agcctatgtc tttactaaca gcgatatctc ttattaacca
    33361 atctatcccc gttgttccta aggttcttga tgttttctaa ggcaatgctt gtatacatag
    33421 cccttgatca aaatattgat actaacgttg acgtttcgat catgatgtgt acggcaaata
    33481 ggacaagtcc attctcgaat tgtgaatgac ttcttaccat ctgtgtgtcc acattctgaa
    33541 ccaatttgac tagacggaaa tcatttatct atcttgatga tttttttgac agaagtatcg
    33601 aaaatcttta cataatctgg gtgttgcatt cttatgcaga tgagagcgtt agctccgtat
    33661 tcataaccag ttgcctctaa aacgtagtcc atcggtggat acctagcttg cggttgccag
    33721 tggctttcgc agtcttcttg taatcaaatc gagcatctaa ttgagtacta gtattttgaa
    33781 gataatactt gagtttttcg gttttcagaa gttcacttca tcttccatca tccatggaaa
    33841 tcccactcac ccatacgcag gcctccaaaa attcttcaac aatggttttt cagacatttt
    33901 tctgaatacc tccttgtttt ttgatacgcc agatagtcag gaaaaaggca acaaaacaca
    33961 aaacaaagct gcctaaaaag gtaatcttca ttccatataa aaagacatcc ggccgatctg
    34021 cgatatagtt agttactcgt tggcccatct tagcagacat cgcttgatat aagaccgtcg
    34081 tagaaagcga aatcccgatg accatcccca aatttcgggc aaaggaattc atggagcctg
    34141 ccagtcccaa attttcgata gtgacagaac tcataaccat cgtattattt ggggactgga
    34201 acaaggcatt gccggcaccc atgatggcag tagcgacaat gtacagccac aaaggagagt
    34261 ccactgacaa aaacatatac atgacttggg ttaccgacaa taaacccaag cctactaata
    34321 caaaaatctc cgggccaacc cggtcggtca ggtatccgct taaaggcgcc ccgacgacca
    34381 tcatcaaggg aaagaccatc atcaacagtc cggcatagct aggactcaac ccgcgagcat
    34441 tttgcagata aaaaggaatc actacattaa caaagaagtt ggaagaaaaa atcaacaagg
    34501 ctgtaatcaa gctcatggta aaaatcttgt tcttaaaaat accgaaagaa atcaatggag
    34561 aggctgcttt cttttcaact tttaaaaagc tgacaaaggc aatcactgaa attacgaaca
    34621 gtacaagggg gactggatgg aaaaagccac tttcttgccc caaaaagatt gttccaaaaa
    34681 ggctgataat cgtagccgca atggcagcaa agccccctcc atcgattgta tggccgctca
    34741 tggtgatatc ttttggtaag aatttttcag caatcaacat cgttacgatt cccaccggta
    34801 cattgatcca aaaaatgtac gcccaagaaa attgggacaa aatcaagccg ccaagacctg
    34861 gtccagcaat cgagcctaat gaaacaagcg caccgattgc tcccaatgcc cgaccacgtt
    34921 catgtatggg aaagacttcc gtgatgattc cggcatttgt agccatagtc atactagcac
    34981 caatggcttg taccacccgt gcgaacaatt aaatacctag cgaatgattg aacccacaca
    35041 acagcgagcc caagacaaag atcagcgtac caatccgaaa tactttgatt ttcccacagc
    35101 tatcgccaat tttaccaaac agcaacaaac aagaacagac aatcatcaga taaacggaca
    35161 ctacccattc cgcttgattc attggtatgc ccatatcatc tgagatggta ggtagtgcaa
    35221 tattgacaat actgccatcc aatgtggaca tgaaggtaaa catagatata gcaatcaaaa
    35281 tccaccagcg atttttttgg acttttgcat cttcttgata actatgcata ataggatttc
    35341 ctttctaatg atcgtgtagc taagaacaat ataacctatg tctactgccc aacaacttct
    35401 cgcgactcta gccataggaa gcttgagtaa tttcgatttg ttattctcat gtaaccatgt
    35461 aagtttgaga tgctttattt gaacttactc tatagtaact agtgataatt cgctttactt
    35521 tcttctagca atttctaaaa gtcgacttca ttgttcttca gattaatagt gtgagctatc
    35581 tcgtgagacg taagaaaatt tccattctac tttttcccaa ttttttcata tttatggtgt
    35641 tgcacctatt tgttttccaa tttgcttttc aaatacattg ctatgatatt caattccata
    35701 ggattatact aaatgtcaat agtatgaata atatattata gatgtttata tatcactgtt
    35761 aattattatc cacaataatt aatgattacc tcgatatttg tcaatcaaag gttgaaacaa
    35821 tttattttca gcatcttttc taacttgagc tgcactctta atagaatcat acgatcctaa
    35881 atagtacctc ttttttttaa agttatatac gcaatccatt tctctttaga acgataaact
    35941 cccttaacac cacttgtatt atttttcggt aattttgacg ttagacactc tattactgtc
    36001 ccttcaacac atgtccttgt ttcttgcctt tttaaacatc cacaactttg agtatgtcca
    36061 aaaaataagt tactataact tatctcacac atactgccac actcacattg acaaacccat
    36121 tttgttttcc atgaacagtt attgtccaaa ggatactttg cagtaagtaa tccgaatttt
    36181 ttattttcaa tgtgatgctt ttttgatttc aaacatccac agctttttac atcacctttt
    36241 agaagtcgct ttgccgatac taactttttt ctcccacaca gacattgaca ttcccaaaca
    36301 acagttcctt cacttcgcag tttagttggc ttgattgcaa ctaacttacc aaaagtttta
    36361 tttgtcaaat ttttatattt atgcctattt ttataatttc cacatccaca acttttggtt
    36421 ctacctgata gtaagtttga tcgatataca atcgtttcat tcccacagtc acataggtaa
    36481 cgatattttt tatatccatt atgagtaatc tcctcaacaa cagtaaggtg accatatctt
    36541 tccttcactg cacctaccct cccaagaaag aagtaccata taatttcaat taacttttaa
    36601 taaatcagaa aaaaatattt tcaatttttc ttagtctgat tttatgacta atttataata
    36661 caagactgaa cgatacgtac acgaaatcct caagatagat aaattgtttt catctagtaa
    36721 aacctgctca aaatatgagc ataaagacgg caataataca ctcgatattc gataatggac
    36781 ttgttttatt tgtcaaactc atcgtaatcg agatatcaat tccagtctca atatcctgat
    36841 caaaggtcta agaatccaac cattttcttg ttactttgtc agattgatta ccttttttag
    36901 tctccgaata ataaggtttt cggatcaact aacatgctct gagaaagact actatctttg
    36961 caaatttcca aatgaaggtg tgggccagta ctattcccag tacttcctac atagccaatt
    37021 atttgtcctt gcaaaacatt atctccagtt tttactaggt attgttgctg gtgagcatat
    37081 aacgcggttg atccatcttc gtgttgtatc accacgtaat ttccccaaga gtagtgaaac
    37141 tctgctttaa caaccttacc agctttaact gcatgaatcg gctcaccctg tgtagctgcc
    37201 atatcaagtc ctcggtgaaa ttcatttcca cgatttccaa acaaactggt tattgaataa
    37261 ttatgaatag gcacttggta tccagtctta ctcatttgtg gacctttaac ttctttatca
    37321 tagttggtta aatcataggt tttaattaat tcatttagct tcaaatagta ttgtgtatct
    37381 gttgcatacc gtcctgtaag gaatttagtt gcttctcgat atgttttact attagctttt
    37441 aatgctcctg cataaaaatc tttatttcca ctaattccct tagttaataa tttggcataa
    37501 tcttcaaaac tttcctcata gttttcatac actctaaatt ttgattgggt cgtataaagc
    37561 gttccattac ccaaatcttc gtttgttacc ataatgacaa agtttccatt ataagttcct
    37621 tttatcccaa ataaattgta attcggtgcc tgagctaact ggctttgacc actggcagat
    37681 tctaagatcg cttgtgcaat cataacagaa gcatataaat catatttctg accaattttt
    37741 ctcgcagact caccaatttt cataataaaa ttttctacag attcattttt gtcaaaatga
    37801 atttcttcat taccagatag tattggttgt gattggaaag attctgttga ttctatttgc
    37861 tgtggtgtcg aaaaattttt tgtttgtcct tccgtttttg gcgcttcctt ttttgaagac
    37921 tctatatggt ttggtcttgt cactttcgaa gaagttattt cacttgtact acttgaagtt
    37981 gttgaagatt cggcacttga aatcgtacta ctttcacttg acgaagttgt tgaagactcg
    38041 gcatttgaag tcgtactact ttcacttgac gaagttgttg aagactcggc atttgaagtc
    38101 gtactacttt cacttgatga agttgttgaa gactcagcat ttgaagtcgt actactttca
    38161 cttgataaag ttgtcaaaag ttcactactc tctgctgtta catcggaatt actcatttca
    38221 gtcgtctcgg ttctttcttt tgcaattttg tatgttgaat tttcgcttgc caacacatgg
    38281 aaaggtgttg ctataaagag ttgggacatt aatataactg ctgatgcaag ttttaaagat
    38341 tttttcattt gatttacctc tcttttttct ctttaatagt gttttctatt aaaaattatg
    38401 ataaatattt tcaatgaatt gagtaataca gtatatttct tgatttcatt tagtaacgat
    38461 tatgtttcaa tgtttaatcc tgttactgcc tttaaaataa aattataggg ttggctaaaa
    38521 ctaggatgaa ataaataatc taacattttc aatttgtcta atgtaatttg ttcttctata
    38581 gcaagagaaa acattgataa tagtccagat aaatcttctt gactacaaag ttgtacacct
    38641 actattctct ttgtattttt ttcaaagcta attcttaatt ttacacgact attttttctc
    38701 aaaaaaacag gtctaatgaa atcttctatt tctatataat ctatagactc acttaataat
    38761 cgtgctgttt ttaaattcaa acctgctgcg taaaaattgt aattaaatat agaaaagcca
    38821 tttgtaaatt gggaaccaga aggtgtaaaa tcttgattgt caatatgttg agttgcaata
    38881 taagctgttc ttagagcatt agaaatagaa aaatcaacac tacttctatt aatggacgta
    38941 aaaaaagttg tagcacaatc cccaatagca tatatatctt ttatatttgt ttgctggtat
    39001 tcattagtta gatatgctcc actaacatct ctcaagagtt cctttttgcc aattggacta
    39061 ttagatagaa atcctatagc ttgtacgacc atatccatag agtattgggt accacttgta
    39121 gtgactattt tttcaatctt ttttcttcct aaatattttt taggactttc tgatagacaa
    39181 agatgtattc cattttttga tagtatttct tcaactttat ctgaaaaact acggtcgtaa
    39241 taagtcgaca acactctatc tgcaacatcg aaaagatata cttctttccc tctttttctt
    39301 atggcttcag caatttcaac tccaatatat cctgctccaa taattcctac ttttttaata
    39361 gtattatcat ctaaagcttt aaaaatctct ttagcatttg gaaaattctt tatcgaaaaa
    39421 atattagcta aattattccc cggtacatct aacataattt gctttgaacc tgtagctagt
    39481 ataagtttgt catattcttg ggaaaatctt gtgccatctt tttttacaca aataatcttt
    39541 ttattttgaa tatcaatttt gtcaactgct gtctccaaaa acaacttttt tatcttagaa
    39601 tttagttctc ttctattttg ataaaaaaga tcttctaaat tgctaacttc tctttttatg
    39661 aacaacgatg tcccacattc taagtaacta atttctgatt ttttatctat cagaataact
    39721 tcataatttg aatcacataa gtttagaaat cgagctgcag ctagccccga atggtttgat
    39781 ccaataatta ctattttttt cacttaatca cattcttttc ccttctatga aaagtatctt
    39841 catttttaac taacaaccta tctcccaaaa taaaaaacaa aaagaggaag aaaaagattc
    39901 ttcctctttt cagagaagat ttaagaaatt gattttctat tcattctctt tttttcgatt
    39961 tttataccct aataacccta aagttcctaa caggattaaa ccaccactaa tagtaaagat
    40021 attactatca atctctcccg tcttaggata agcttttgag gactgctttt gaggactgct
    40081 tttgcctcta tttttgtttt gcttgctacc ttgattgtca gtcttattat ctttactaac
    40141 ggctttttca ctgtcttttt cgtttgaaga aacaactaca ttagtaggtt cactagtatt
    40201 accagattca tcagttgcag ttactatcac ttttgttcct gcctctaatt taggaacttt
    40261 aactgtaaaa ttaccatttt tatcagctgt cccatggtat tgactcccgt ttggtaatgt
    40321 aactgtcacc tctgcatttg gttcagtttt accagtaaca atttggtcac cctctgtaat
    40381 aggatcaact tgaggtttat tcggtgcttt tttatcttct acagaaatag taacctctac
    40441 ttcttcttta gatccatctg gatatgttac tactacaatc ccttttttgt ttccagctgt
    40501 actaacatct actttctctt tccaagtata agtagttcct tttggtagat cttctttgtt
    40561 cttaattccc tcagatgcgt ctggctcttt atttaagtct gtagtcactt tttgtccttc
    40621 aggattgtat ttatcggcat cggaacgatt gtctgtcact tctactggaa ctttcactgt
    40681 atctttcgta ccatctggat acgttacttc gataacccct tcgtaattac ctggtgtgtt
    40741 ggtatcaatc gtaccatcag gagtgacatc tgttactgtt gttccttctg gtaatgttgg
    40801 caagttagta acattatctg ttagatctac tgtgcctcca acttctactt tttcgccttc
    40861 tactgttggc tcatatttat cggcgtcaga acgattgtct gtcactgtaa catctacttc
    40921 aacttcatca gatgatccat ctggatatgt cactacaaca gtcccttttt tatttccagc
    40981 tgcgctaaca tctacttttt ctttccaagt atacttagta tcttttggta aatcttcttt
    41041 gttcttaatt ccctcagatg cgtctggttc cttattcaat tctgtagtca ctttttgacc
    41101 ttcaggatta tatttgtcag cgtcagat
//
LOCUS       DAZKKZ010000020        38819 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.020, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000020 DAZKKZ010000000
VERSION     DAZKKZ010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 38819)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38819)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38819
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.020"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            34..657
                     /locus_tag="ACG8LA_001141"
     CDS             34..657
                     /locus_tag="ACG8LA_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0203450.1"
                     /translation="MFVIWEVVKSRVQEMNEHFSVSFAENPSKYFRRLVFLLILSLLL
                     TVAMFLLPEKIREEQVNSLVYSSIPTSKLKPFDYSKADQKIKQSRAISVMFSKPNGKT
                     YQDMLDVFNDPELMEELNRPIFYYPIVYDVHELEQKYNIRTDEVTFIFFDGGKEANRI
                     TAGKGGITDFDKELIPELNRLPLANIKQLEEELDRTGVTSQNSEIAN"
     gene            1107..2156
                     /gene="trpX"
                     /locus_tag="ACG8LA_001142"
     CDS             1107..2156
                     /gene="trpX"
                     /locus_tag="ACG8LA_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan ABC transporter substrate-binding
                     protein"
                     /protein_id="HFQ0203451.1"
                     /translation="MKNKRLITVVVIILVYLAGAFIYGKASGEKESTSTNQTKKTTVV
                     GVLQYVSHPALDEIYRGIKDGLKEEGLKEGENLEIKFQNGQADQSKLATMSQQLVQSD
                     PDALIGIATPAAQSLANTTSSIPVVLGAVTDPVGAGLVASLEKPGGNVTGVSDQPPVT
                     SQIKLASDLLPNAKKVGILYASSEDNSKYQVAQAEEAAKKEGLESVKYAVPSTNEIAQ
                     TVQVMSRQVDFIYVPLDNTIANAMQTVVKEANKANIPVIPSVDTMVEQGGLATIGINQ
                     YQLGLQSGKMAAELASGKEKPETTPVYTFDQGDTVINQSQADRLGIIVPQSMKEKAKI
                     ITDDSQQETSKEDDK"
     gene            2153..3034
                     /locus_tag="ACG8LA_001143"
     CDS             2153..3034
                     /locus_tag="ACG8LA_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFQ0203452.1"
                     /translation="MIVSAISQGMLWAILGLGIFMTYRILDFPDMTTEGSFPLGAAVC
                     VTAITHGVAPIVATLLGVGAGMIAGLVTGLLYTKGKIPVILAGILVMSGLNSVILFVM
                     RTPNLSLLNHPILQDSFHRFGLPDYFDTVLLGFISLGILIAVLLFFFNTDLGQGYIAT
                     GDNETMARSLGIKTDRMKILGLTLSNGVIALSGALIAQNDGYADVNKGIGVIVIGLAS
                     IIIGEVIFQELTLAERLIAIVVGSIIYQLLILVVIKLGFDTTYLKLFSAIILAICLMI
                     PQLKKALNLKTGFEKEA"
     gene            3037..3807
                     /locus_tag="ACG8LA_001144"
     CDS             3037..3807
                     /locus_tag="ACG8LA_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0203453.1"
                     /translation="MTDILTIKNGRKVVNNGMNEEKVLLDEINLTIREGDFITVLGGN
                     GAGKSTLFNTIAGTLQLSQGSISFKDQLITKDSEEKRARFLSRVFQDPKMGTAPRMTV
                     AENLLLAQKRGQKRKFRLRNLKNQKEDFFRLCQEVGNGLEQHLDTPAGELSGGQRQAL
                     SLLMATITAPELLLLDEHTAALDPKTAKALMRLTNQRINEQKLTCLMITHRMEDALKY
                     GNRLIVLQKGKIVQDISEKEKQHLTMGDLLQFFEEVVD"
     gene            4086..4940
                     /gene="aroE"
                     /locus_tag="ACG8LA_001145"
     CDS             4086..4940
                     /gene="aroE"
                     /locus_tag="ACG8LA_001145"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004764 - shikimate 3-dehydrogenase
                     (NADP+) activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0019632 - shikimate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HFQ0203454.1"
                     /translation="MISGQTKLAGLFADPASHSLSPLMHNTAFEANNIDAVYLAFQVN
                     PMNLKQAVESIRTFDMLGVNLSMPNKTAVIPYLDEVSQEAQLIGAVNTIVHEKGRLIG
                     YNTDGAGFMQSVQEAGISIKKKKMTLLGAGGAAKAVTVQAALDGAEEIVVYKRNNQTF
                     AQVKETFEQLSYRTSCKIKVRDFADTHQLRKDLKESCLLVNATDIGMGKKINQSPLLD
                     ISMMHENLAVFDLIYAPRETRLLKEAKKVGAKGYNGLGMLIYQGAIAFELWTKEKMPI
                     HVIEKLFD"
     gene            5118..6281
                     /locus_tag="ACG8LA_001146"
     CDS             5118..6281
                     /locus_tag="ACG8LA_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0070726 - cell wall assembly [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HFQ0203455.1"
                     /translation="MSRMDRYKDIHKKAKPLKRDTGSIFARRERKRTRMENEEDATRI
                     YEREQHSFEHLNQYEQQIYRDAPRAEEQQKNKKFFNRQKKNKPLKPRRKRSWKKIILS
                     ILLVLILYSGISFFIGKYVAEHDTSLEAATSETFHGQKATNGAHNILILGSDTRGEDA
                     GRADTIMVLQLDGPSHKPKLISFMRDSFVTIPGVGQNKINSAYAYGGADLVRQTLVEN
                     FGIDCQYYAKVDFKSFEKVIDALFMNGVKIDAEKDLNLDGVDIKKGVQKMDGHVLLQY
                     ARFRMDEQGDFGRVRRQQQVMNAIFSQLKNPLNLIRAPYAAGKALGYTSTDVTAWFLT
                     KNLFSIARGAGGIDRISVPVDGSWNYGQSDYAGSILEIDNQMNQSAITDFLNK"
     gene            6398..6808
                     /locus_tag="ACG8LA_001147"
     CDS             6398..6808
                     /locus_tag="ACG8LA_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFQ0203456.1"
                     /translation="MDIYLNFKNESREAIAFYEKVFQTEASGITTYGEMPGIEQMNLP
                     EEAKNLITNARLNIYDTLVMFADTPEGIGPELVVGNNVSLVIQTRNEEETKRLFESLA
                     EGGKIEMPLDAVPWAQLYGMVTDRFGINWQINQE"
     gene            6982..9210
                     /gene="topB"
                     /locus_tag="ACG8LA_001148"
     CDS             6982..9210
                     /gene="topB"
                     /locus_tag="ACG8LA_001148"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HFQ0203457.1"
                     /translation="MKTVILAEKPSQAKAYAETFQQQKRHEGYYEISDPLFAGEVTIT
                     YGFGHLVDMVAPGAYEERWAKWSLENLPIFPETFRYEVPMDKRAQFSIVKRELQSADT
                     IIIATDGDREGEAIAWSIIRQANAFSKEKNYLRLWINSLEKEAIYEGFKNLQPGKNYF
                     PKYKEAQARQNADWLIGMNGSPLYSLLLQRKGIDGSFSLGRVQTPTLYMIYQLQEEIK
                     HFKKETYFEGEGLITTNKGQFSGKIVPKKAFKTQEELTKEIEKLGAHLGKQNGRILEV
                     TKKEKRLHSPRLFSLSSLQTKMNQLMKASAKATLDAAQGLYESKFLSYPRTDSFYITE
                     NEHQYLVKHLQNYKKFLGIEEVQTTEIKAKKRYVDAKKVQEHHAIIPTKTIPTPARFA
                     KLSKLQQAIYLQVLRTTVAMFAADYIYEETTVMTGVQQLKLKSIGKIPLQQGWQEILR
                     IKSKKKEAQTLPPIVENEEAEVELKSMEKETQPPKPYTEGTLITAMKTAGKTLDNDEA
                     QEILKEVEGIGTEATRANIIENLKQKHYIEVNKNEITVTPKGITLCKAVANEPLLTSA
                     EMTARWEGYLRKIGKQEGTPSVFLENIKKFILHLLAEVPNQIDKVDFSDEISGTRQIK
                     AMEKKNDQLGRCPKCKKGIVMLYPKIATCLNPECDFKLWPTVAKKKLTKTNLRDLLSK
                     GKTSKVVKGFTGKKGKFDAVLVLKEDMTIGFSFPWIENSGTKAVDGNKETSRKNNENE
                     VE"
     gene            9381..9665
                     /locus_tag="ACG8LA_001149"
     CDS             9381..9665
                     /locus_tag="ACG8LA_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0203458.1"
                     /translation="MGAITIVAVYQAFLKYPDYGTKLLSLTHNQTAYSPTLILSTLTA
                     GAKSATYFFHKTTSMLKRKKQRKQLLVVVAAMIIIYFLPVITQVFHQYFG"
     gene            9825..10061
                     /locus_tag="ACG8LA_001150"
     CDS             9825..10061
                     /locus_tag="ACG8LA_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HFQ0203459.1"
                     /translation="MKKMKKYKIRKSGNSDVTTIPPEVKEFMGVQTGDAISYVFQSDG
                     SVRMIKAQEEPDIDSLVDSIMNQYEDALKDLVDL"
     gene            10058..10456
                     /locus_tag="ACG8LA_001151"
     CDS             10058..10456
                     /locus_tag="ACG8LA_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HFQ0203460.1"
                     /translation="MRYLSTKEIIKINAKVILRHSPGEMIGVKDANALDMAVKQPSQA
                     VFNQELYPEIYEKAAILAINLAKKHPFHNGNKRTALVAMLLFLQLNNCPVAFSRQEAV
                     DFIIMITTSSLDFDSLKSKITSYLRQTAIK"
     gene            complement(11123..12067)
                     /locus_tag="ACG8LA_001152"
     CDS             complement(11123..12067)
                     /locus_tag="ACG8LA_001152"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004459 - L-lactate dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HFQ0203461.1"
                     /translation="MKKTSRKVVIVGTGFVGTSIAYAMINQGISNELVLIDVNQEKAE
                     GEALDLLDGMAWGDENVAVWSGGYEECKDADIVVITAGINQKPGQSRLDLVKTNASIM
                     RQIVKEIMGSGFDGIIVVASNPVDILTYIAWNESGLPTSRVIGTGTTLDTTRFRKEIA
                     LKLKVDPRSVHGYILGEHGDSEVAAWSHTTVGGKPVFEIVEKDHRIAQDELDVIADKV
                     RNAAYEIIDRKKATYYGIGMSTARIVKAILNNEQAVLPVSAYLTGEYDEKDIFTGVPS
                     IVDENGVREVVELSINEEEKAMFSKSTSALREVLNTVL"
     gene            complement(12363..13307)
                     /locus_tag="ACG8LA_001153"
     CDS             complement(12363..13307)
                     /locus_tag="ACG8LA_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HFQ0203462.1"
                     /translation="MRNEESIETLQREQGMNINDLNLAYHLQTPPKIHRGDLFQQGNI
                     HISKHRRYAEVPEHTHDFVEINYMYSGTCLQIINGERIEMEESDVVIIDKEATQRIEY
                     TGQEDILINILLKEETLSTEILNHLASTNNLLSSFLINASKEKGEHTQFIHFRGGKTS
                     RLTHLIENMLLIYFDTYSHKIRSLNLYTSLLLIELTHLLEQQSFSSADGCAENEMLRV
                     LDYIDKHFTSCTLKETAAHFGYNPVYLSNKLKMYFDASFQELVLKKKFDFALELIQET
                     SFSLEEIANRIGYKQTTSLFKLFKKYSTCTPNEWRNKH"
     gene            13528..14742
                     /locus_tag="ACG8LA_001154"
     CDS             13528..14742
                     /locus_tag="ACG8LA_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFQ0203463.1"
                     /translation="MLMNKKMMKFSLLSVSLILTSAGAVTSAIPSMSATYATRSLSAV
                     ELLTTAPSFMVTIFVLISSFIARKIGQKQTVIIGLVIASICGILPLFSQSYSIVLASR
                     AGLGIGFGLINSLAVSMIAAFYHGDERASMIGFQSAFQGFGAALMTFVAGQLVQFGWQ
                     YTFLVYAISLPILVLFVLFVPTPETTELQSHGTAPTRQVIKTNPKMISYGIFLLLVIV
                     VYNAVSIKLATVLTTYSLGNETNAANILTIMQLASMAAGVCFGWLQTKAHRYMLTLSL
                     LLMGIGFVLIATVINLYVIGFGAILTGISFSLFIPYLFNQVSIQAPKYAESFNTSILL
                     VGANLGTFIAPYGLLFLSFASLGSKTLAVFVNGSILLLISALISLLVVHRTNRKTVIR
                     VDEEIKEQLTTK"
     gene            14764..16779
                     /locus_tag="ACG8LA_001155"
     CDS             14764..16779
                     /locus_tag="ACG8LA_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 78 glycoside hydrolase catalytic domain"
                     /protein_id="HFQ0203464.1"
                     /translation="MTNEKHKDRWLWYPGDFEIRHGLLQNFQREERGFDWPAYWYMDD
                     CHRNVKFKRYYFLDQPSMFKVTIQGVGYVEINGQKHPCGKWLTCPAGKAKIRIFVGHT
                     SGLPAMFIEGDEVKSDIGWTASNFIEEYPAGWSPLYVDIAKDPNQIYYQKECVHPVTE
                     TEIGGGILFDFGRAVNGCVELISLDDHIESITLCYGESDVEAMDIDYCYYKQIGMTRK
                     MKARKRAFRYLFIPEVSTGMVQLQVFHEFLSLSKQAAFSSDSSLLNQIWSVSEEAFKL
                     CSDLFFIDGIKRDRWIWSGDAYQSFMINQYLFFDEEINKRTILALRGQNEIKQHMNTI
                     VDYSILWLIGIENHYMMTKDYEFLRIVYPKMQSLMRYLMEQTNELGFIYGRAKDWIFI
                     DWSEMDKEGTLAAEQVLLLKAYHSMITCGDILAETYGENENYHTHLYQEKYQLLKQNL
                     FDYFWDEELGAFIDCYESGRRNVTRHANIFAVLFDFANKDQQQSILKNVLLNDTITQI
                     TTPYFKFYEQDALCKLGQTNIVYQTILDYWGGMLSHDAVTFWEEYDPTQTGNEKYSMY
                     GDPYGKSLCHAWGASPIYLLGRYFIGLYPTKPGYEEFMIQPNLDSFETLNCTLPIKDG
                     KISLEKTKDKIVITSDRTGGTVKMNGKSYPLLAKQPLVLTSYSKINA"
     gene            complement(16862..18235)
                     /locus_tag="ACG8LA_001156"
     CDS             complement(16862..18235)
                     /locus_tag="ACG8LA_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HFQ0203465.1"
                     /translation="MDKLLNLFVSIVSQPSILVSLIALLGLVLQKKKFSEVIQGTIKT
                     FVGFLVLIGGAGLISNSLTPFASMFQTALHTQGVVPSNEAVVAIALQQYGTPTALIML
                     VGMIVNILLARFTRYKFIFLTGQAMLYVSCLTAVILVSAGFTANLWMILLGGVFEGTL
                     LTITPALCQPFMKNITGNNQVALGHTGNIGYASSGWIGKFFGNKDRSTEDIKIPKSFS
                     FLRDSTVSIMLLMSIVYVALALLAGPGFVERELSNGDNAVIFALIQAGTFTAGFVIVL
                     QGVRMVLAEIVPAFQGIAKKLVPDSKPALDVPIVFPYAPNAVLIGFFVSFFVGTLSMF
                     AMIGLQTTVIIPGVVGHFFCGAASGVFGNSTGGRRGAVLGSAFNSLLISWLPLFILPV
                     LGDLKIASSTFADTDYLVPGLVLGKLGEYGQIALTVGIIAFFLLVVLSSFLFAGKRTN
                     IVSKEQN"
     gene            complement(18261..18545)
                     /locus_tag="ACG8LA_001157"
     CDS             complement(18261..18545)
                     /locus_tag="ACG8LA_001157"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFQ0203466.1"
                     /translation="MKIFAVCQSGLGTSFMVEMNIKQALADLGADVDEFEVSHTDVGS
                     VSSDMADYFFIEHSLKDTLTSIPDEKLVPLQSIIDSEEVKEKVTKILSKE"
     gene            complement(18547..20562)
                     /locus_tag="ACG8LA_001158"
     CDS             complement(18547..20562)
                     /locus_tag="ACG8LA_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HFQ0203467.1"
                     /translation="MNYKISYLLKTPREISLEKAAEIIEVNTSEAIKQLTPFAEYVDD
                     TRIRIKKFRAIDWAEKFLDITRFEAVYTEQERRDLLYLMVYSTATSVSVFHFQDFLQV
                     SKGTVLSDIKKIRNELEVEDCQLSYTRKTGFRLLGSEAILRREAKNRTARLMQSLAGR
                     FGLTYLTATLSIDYYAKVRDLLDKTISLSDLRFAPNRMDELAYYLSLTTIRIGKTSME
                     LVKDAELLASLAVTDISRQVLTGLGYSEHQNSEIIFFSLCLASIVEGDVQEPALDFLL
                     ECSSEVIHRMEFLMAVEFASFRELLMNVFYHLVPAYFRISYSFYLPNVMIDQIKHQYA
                     SIYEMTRKALLPLERRIGKSIPEEEIGFFTILFGGEIRKADAEERNRKIRAVIVCPSG
                     ISSSLILKSELQQLFPMIFFTETNSADRLHEVDETSYDIIFSTVPLTLTDKKKSLYVL
                     HPIMTDLEKNQLINQVQRDWLIPGFSMPSAQELLSALLPYIELKEGVDEEKLYQVLNR
                     KMNKLLEKKEDQRPMLSELLTEEMIQLSDQPKNWQEAITFAAQPLLSENKIEESYIKA
                     MIERVEQYGAFIHIGDHIALPHARPEDGVNEVGMSLLKLQQPVDLLDNPAHPISLFIC
                     LAAIDNEAHLRALANLTKLLSNKQNLQDLLHASTKEEILAIIRKGDE"
     gene            complement(20741..21046)
                     /locus_tag="ACG8LA_001159"
     CDS             complement(20741..21046)
                     /locus_tag="ACG8LA_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA processing protein"
                     /protein_id="HFQ0203468.1"
                     /translation="MTNYDGEKHKRLRGSMAPKTEEEVALAGTNSGETEDKEESLAGT
                     NSGETENKETALSGSNSVEEETKPNEPNHFEKDIEKAVEDVKEKFEELTSKNKHDHH"
     gene            complement(21135..22166)
                     /locus_tag="ACG8LA_001160"
     CDS             complement(21135..22166)
                     /locus_tag="ACG8LA_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFQ0203469.1"
                     /translation="MLTIAYLGNGKSTNRYHLPFSRKLTNKINIKKIFSPSEPVWKTF
                     EDIEYTDQLSDLWDDPEIQLVVITTPSQFHYEYGKMALEHGKNVLVEKPFAETSKEAE
                     ELFALAKEKGLFIQCYQNRRFDSDFLTVQKVIESGKLGDILEVEMHYDYFRPEVPENT
                     HEFSTANSYLYGHACHTVDQVLSYFGEPDDISYDVRQLLGKGRMNDYFDLDFFYGNMK
                     ISIKSSYFRIKERPSFVVYGKKGMFVKQTKDRQEEHLKMFYMPDHEDFGIDLPEHYGV
                     LTYIDEQGSYHEEKVISEVGDYSRVYEGIYETLVNGAEKVIKDEETILQMKILEEGIK
                     SIQESEGKI"
     gene            22373..23248
                     /locus_tag="ACG8LA_001161"
     CDS             22373..23248
                     /locus_tag="ACG8LA_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HFQ0203470.1"
                     /translation="MLIEEKLTKQELFTTTEKRIVDYIRRNIEAAVYMTIEELAKATY
                     TSHSAIIRLCKKMGFSGFKEFRFELGREVHQLIAQFNQTIDPNFPFSSEDSTQQIAKK
                     MADLSIQSIKKAQLQIEHEDLDQIGKVLNKAQRIFLFAKGDSQITARKFQNKMVKLNK
                     FLIMAEEYSDSSWNAANLTSEDCAIFISYSGRIHHYERIMTYLKHVEAPTLLITGNQH
                     SEMAKQADMCLVISQEEYDFAKVATFSSQIAFDYVLNTLFSVIYSQNFEENIRNLKNK
                     QELMQKGLLKEYRKT"
     gene            complement(23400..24242)
                     /locus_tag="ACG8LA_001162"
     CDS             complement(23400..24242)
                     /locus_tag="ACG8LA_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HFQ0203471.1"
                     /translation="MKPKKRKLLDLLMLFLLLSGIGILAYPFVSDALNNYLDQQIISH
                     YQQQAVKENEEVMAKIQENMTKKNQQLAKEGGNPGADPFTKKKEPAKKDRTYFEKHTI
                     GILTIPEINVHLPIFDETNTVLLEKGASLLEGTSYPTGGENTHAVISSHRGLPQAKLF
                     TDLPKLTLGDSFYIEINGRTLAYQVDQIKTVEPTDTKDLRIEKGQDFVTLLTCTPYMV
                     NSHRLLVRGHRVPYHAKEVQKEVQKVSENKRFFLYGLLAACILIFLLLIYLFRQSFKI
                     RNRS"
     gene            complement(24334..26211)
                     /locus_tag="ACG8LA_001163"
     CDS             complement(24334..26211)
                     /locus_tag="ACG8LA_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HFQ0203472.1"
                     /translation="MKNHKKINVMLGVLFLILPLLTNSFGAKKVFAEETAAQVILHKK
                     KMTDLPDPLIQNSGKEMSEFDQYQGLADISFSVYNVTQEFYAQRDKGASVDAAKQAVQ
                     SLTPGTPVASGTTDADGNVTLSLPKKQNGKDAVYTIKEEPKDGVSAAANMVLAFPVYE
                     MIKQADGSYKYGTEELDTIHLYPKNTVCNDGTLKVTKIGTAENEALNGAEFIISKEEG
                     TPSVKKYIQSVTDGLYTWTTDQTKAKHFITGHSYDIGNNDFAEASIEKGQLIVNHLEV
                     GKYNLEEVKAPDNAEMIEKQTITPFEILANSQTPVEKTIKNDTSKVDKTTPQLNGKDV
                     AIGEKIQYEISVNIPLGIADKEGTQNKYTTFKLIDTHDAALTFDNDSSGTYAYALYDG
                     NKEIDPVNYSVTEQTDGFTVSVDPNYIPSLTPGGTLKFVYYMHLNEKADPTKGFSNQA
                     NVDNGHTNDQTPPSVDVVTGGKRFVKVDGDVTSDQTLAGAEFVVRDQDSDTAKYLSID
                     PSTKAVSWVSAKESATVFTTTSNGLIDVTGLKYGTYYLEETKAPEKYVPLTNRVAFTI
                     DEQSYVTAGQLISPEKIPNKHKGTLPSTGGKGIYVYIGAGVVLLLIAGLYFARRKHSQ
                     I"
     gene            complement(26208..27629)
                     /locus_tag="ACG8LA_001164"
     CDS             complement(26208..27629)
                     /locus_tag="ACG8LA_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HFQ0203473.1"
                     /translation="MKKLGWLSMCLFLLLFKPAFTQVATETETEMVQITLHKLLFPNG
                     QLPKNHPNDGQEKALLQTYRGLNGVTFQVYDVTDSFYHLREKGKTVEEAQAEIAKNGA
                     SSGMFTAEATTTTLNNEDGIASFSLAAKDQEKRDKAYLFIESKVPEVVKEKAENMVVV
                     LPVHGQNNQKLSTIHLYPKNEENDYPDPPFEKVLEEPRNDFTIGEKITYSLHTTIPVN
                     ILDYQKFELSDSADEALTFLPNSLTISSNGEKLTEGFVIHKKPHGFDVLFSIPSLEKY
                     AGKKLTISYQMQLSSTAQANKEINNNGTLDFGFGVSTKKVSVYTGSKQFVKIETNKPD
                     KRLAGAVFLIKNKAGNYLQQTANGYKWTKNESDALHLISDKNGAFSISGLKTGSYRLK
                     EIEAPSGYILSETEIPFTISTFLSEDKEADSILKVVNKKENSRPFLPKTNETKNTLLG
                     VVGMVFASFAIWLFIKKRTGVKK"
     gene            complement(27632..31021)
                     /locus_tag="ACG8LA_001165"
     CDS             complement(27632..31021)
                     /locus_tag="ACG8LA_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaA isopeptide-forming pilin-related protein"
                     /protein_id="HFQ0203474.1"
                     /translation="MTTTGKKLKVIFMLIILSLSNFVPLSAIADTTDDPTVLETISAE
                     VISDQSGKKALNIKLNANNTSAEKIEKEIGLVENYLSDVERKEGDGYAYQVNSGKITL
                     EISSNTKQTIDLSFPIDPALYHSQANKLIVDNKEYDIIDETENKKDTDVSVPKPDEIE
                     EESSKENENSVSPFTLPTLSLPAVSVPSNQTIPTEYTTDDQGTYPKASWQPTGNTNVL
                     DHQGNKNGTNQWDGINSWNGDPNDRTHSYIEYGGTGNQADYAIRKYAKETSTPGLFDV
                     YLNARGNVQKDITPLDLVLVVDWSGSMNDNNRIGEVKIGVDRFVDTLADSGITDKINM
                     GYVGYSSEGYSYSNGAVQMGSFDSVKNQVKSITPSRTNGGTFTQKALRDAGSMLSVPN
                     GHKKVIVLLTDGVPTFSYKVQRVHAQSSSNYYGTQFSNTQDRPGNTSLISRIYDAPDQ
                     NNLSRRIDSTFIATIGEAMALKERGIEIHGLGIQLQSDPAAGLSKAEVESRMRQMVSS
                     DEKGDLYYESADHATDISEYLAKKAVQISATVSNGQINDPIAEPFIYQPGTLSVKSVG
                     TSPTTVTPSISIEGNTIKSNQIYLGKDQEIQIHYQVRIQTENEDFHPNFWYQMNGRTT
                     FQPNIDTNELAEFGIPSAKAPGVSLHIKKLWEEFDNNLADRPDQVTFEIQREHTTNAA
                     AWKNGYIRIIKPAKDTTNTWERADIDKLSANSGESYQEILSLPQYNNQGQAFSYQTIK
                     ELPVPGYDSQQIDAMTWKNTKQFTPLNLKITKNSSTGEKDLIGAVFKLTGDSIDTLLT
                     DHGDGTYSLPENVKLQKEMTYTLTETKAPEGHGLSKKTTWEIKIASDGTVTIDGKTVT
                     TSDDTIQLTIENPFVEVPVAVRKYAMQGTDKEINLKGAAFSLQKKEANGTYQPIDSQT
                     TNEKGLASFDSLTPGKYRVVETAGPAGYDTSPGNYEFQIDKYGKIIYTGKNTEMTNNV
                     WTLTHQNRLKAFDLTVHKKEDNGQTLKGAKFRLQGPEMDLESPKDGQETDTFLFENLK
                     PGTYTLTETFTPEGYQGLKEPVTIVIHEDGSIQVDGQDHESVLSPGAKNNQISLDITN
                     QAKVPLPETGGIGRLGIYLVGMIGCAFSIWYLFLKKERGGS"
     gene            31278..32669
                     /locus_tag="ACG8LA_001166"
     CDS             31278..32669
                     /locus_tag="ACG8LA_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0203475.1"
                     /translation="MEKIIRILSISDKWMTKKELAKRIGSSESTFVRYIEEIKIRWGT
                     DVTIQSSQKLGYRLEHLNVPAYLNVLMEMSQSSTNSRLLNEIIVNPGKTIEYYCEKIS
                     ISRSSFTRKLKQCNQILESYLLKVIVDQGFQLTSLKSELQLRIFVTFFFLSYYGRRTL
                     PFPIEKKKIKEIMVKNNCQMNLFQEESPYEQSFFIMYFVVHLMRESQGTPFEWKAGDS
                     YVQLINIDKKDFLILKNLLGKLKYSSYIKVVNYFVNTIFSEFSEKEKNEISEQIRKNM
                     SYCSFSSADCKEKNEEYVVQLLTQIYFFSRIFPYDTTHLTIRATYFAQQMQHRQIRLY
                     AGFRAELQFYSTLLNQNLIYYLSSYIFWMLIGNPEIHHYTSDKKILIISDLSLRHSQY
                     IEEYISDILAVHKIHSETTAITEDQLSKYNLLEYDLIVTNQPILNAHVPHILIDDSVS
                     FANEEELIRLFEL"
     gene            complement(32742..33389)
                     /locus_tag="ACG8LA_001167"
     CDS             complement(32742..33389)
                     /locus_tag="ACG8LA_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFQ0203476.1"
                     /translation="MTMKGYPRIIRDKGEMWMPKETFFNLSNAKKQRIDDLLLEIFCS
                     QHISQVKVSEIVDKMGMSRGAFYKYFQDLEDAYLYTIKSSSHIVHQDILKFISENKQH
                     FFLGIEKYLEWCCDLDHESIYWQRLYLLTQRNDQQTTKRRELSADSPMNEKWLELLRI
                     NHFSIQSSEEAVSFLYFSMTLVMNTLTDLIANNWTKEELLKDFRYKSRWIAEGIQ"
     gene            complement(33397..34083)
                     /locus_tag="ACG8LA_001168"
     CDS             complement(33397..34083)
                     /locus_tag="ACG8LA_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002366355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0203477.1"
                     /translation="MKKILTMKKVTKTFGSGHTKVSALKAIDFYVKEGEFVSIIGPSG
                     SGKSTFLTISGGLQTPTSGEIVINGHSLTELPEKKRADLRFKEIGFILQSSNLIPFLT
                     VKEQFELVDQVTSKKEDSTKIDSLLQSLDIQSLKNSYPKDLSGGERQRVAIARALYNE
                     PSLILADEPTASLDTDHAYEVVKLLVKEAHEKQKATIMVTHDVRMIQWSDRVYRMEDG
                     YLTEEEKKKE"
     gene            complement(34089..35162)
                     /locus_tag="ACG8LA_001169"
     CDS             complement(34089..35162)
                     /locus_tag="ACG8LA_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFQ0203478.1"
                     /translation="MFLAIKEIRYSKLRYGLIVGIMFLIAYVVFMLSGLANGLSEEFK
                     KAIDDWDAQEIVLSEDANQVFAASQLTRGDLKYIEGGEKAPIGLYSGAIKGKNKENVT
                     VFGTTKEAFLLPKLTKGHEFKTKNEIIISQNLADSGYKIGDTIKIGSYDDPLTIVGIF
                     PETYYTVSPVIYASLDTWTALKYGQQPFASEEEQPINGIVIKDSAKISKEKASKGLQL
                     LTIGTFIESIPGYSAQNMTLNAMIYFLFLVVAAVVGIFMYVMTLQKTAIFGVMKAQGI
                     KNFFIAKSLVAQSFIVGVVGVLLALLFAYLTSLILPSAMPFAVFWSQWLLYSGILIIV
                     AMLGGLFSIRTITKVDPITAIGG"
     gene            35384..36058
                     /locus_tag="ACG8LA_001170"
     CDS             35384..36058
                     /locus_tag="ACG8LA_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFQ0203479.1"
                     /translation="MIKLLVVEDDKVLSNNIKEILAAIGEITQVYDGSEGLFELESGV
                     YDLAILDLMMPEMNGYEVLAKIRKEKIQTPVLILTAKDSLEDKIEGFERGADDYLTKP
                     FYREELIMRVKALLKRSLGLFDENVLKYKDISCDLKSNEVLYKEQVLPIQGKEFELLV
                     YFLQNKGIILTKEQIFDRIWGFDSDTTITVIEVYMSNLRKHLRSTGLDKEIKTLRNVG
                     YILQRV"
     gene            36063..37403
                     /locus_tag="ACG8LA_001171"
     CDS             36063..37403
                     /locus_tag="ACG8LA_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="HFQ0203480.1"
                     /translation="MNGDITRKQRSRFFATNVAAFAFIFFLLGFITLQILNQSAYRET
                     DLSLEKINFDSRTVQLEIQRYQQGDPFLNPTQTEQNRTNMEQPLMEPSNDRFNTQVIL
                     WSKNGEILNKAAIGGRFNQIKELKMDTKNLNTIQNIELNEDSGSSALSFRSITKKAET
                     NQDGVAYIQILENTNQIKNSLATFRTIMILCMIVFWILSIGISYYLSSLSMRPIILSW
                     RRQKEFVENASHELRTPLTIIQNSLEHLFTKPNHTIIEESESIAQALSETRRLTGLTS
                     DLLTIARNDSDQQLLSKQMINTQEYIEQLVKPFQEMAIIDGKEFILHNDATLEVPIDE
                     KKIHQVLVILLDNALKYTNPEDKIILDSSVNHKEWLIHVKNTGPSISEEDQARIFDRF
                     YREDQSRAKETGGYGLGLAIAKQVIEQHHGQISVSNYLPQGVDFKVQLPLKPKK"
     gene            complement(37552..38538)
                     /locus_tag="ACG8LA_001172"
     CDS             complement(37552..38538)
                     /locus_tag="ACG8LA_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2382 domain-containing protein"
                     /protein_id="HFQ0203481.1"
                     /translation="MEEKNLTVIGSYSTREEALSVIERLRNEGYERDDIVIYTTDEAA
                     SRLGFDGLSGIDVETDENRMDGEEDRSLWEKIKDTFSFDTYDSETATPENDPLYQYRG
                     DISDGKFVITVKGYRQPETTEDTMDTQDTVSPASTMGTGLETGTGTDPMDVGGTTGFQ
                     NTTDPLNMTPGTDPMDVPGETDTMGTSKTEDIDRKPNLDDDTIQLKEEKLDVNTHDVT
                     TGEVDIHKHVVNDTETVEVPVKREEIVIERKPVTDQSSQGTDEKLEDDTITIPIKEEQ
                     VDVSKHTVIREEVGIHKEEHEDVEKVTEDVSREELDIDTSGDVHIEDRNKKS"
BASE COUNT        11968 a         7065 c         7333 g        12453 t
ORIGIN      
        1 taataaaaaa taggagaaaa agtagaaaag aaggtgtttg ttatttggga agtagttaaa
       61 tcgagagtac aagaaatgaa tgaacatttc tcagtgtcat tcgcagaaaa tccaagtaag
      121 tattttcgac gtcttgtttt tctgctcatc ttatcattgc tgttaacagt tgcaatgttt
      181 ttattgccgg aaaaaatccg agaagagcaa gtaaatagtc tcgtttattc gtccatacca
      241 accagcaaat tgaaaccttt tgattacagc aaagctgatc agaaaatcaa acaaagccgg
      301 gcgatatcgg tgatgttcag caaaccgaac gggaaaacct atcaggacat gcttgatgtt
      361 tttaatgatc ctgagcttat ggaagaattg aatcgaccga tcttttatta tccgatcgtt
      421 tatgatgtac atgaactgga acaaaaatat aacatacgaa cggatgaagt gacatttatt
      481 ttctttgatg gaggaaaaga agcaaatcgg ataactgcgg gtaagggagg aataactgat
      541 tttgataagg agttgatccc tgaactgaat cgacttccgt tagccaatat caaacaatta
      601 gaagaagaat tggatagaac gggagtaact tcccaaaatt ccgagattgc taattgagac
      661 attggcgcga tgaaacggtg ggtctatata gcgctatttt taattatcag aacaagtgat
      721 gtttgatctt caaaataaca aataaaaaat taaaaaatat agttgacgaa attcaaaaat
      781 tcgattagac ttaaatcaat tcttaaggaa agggtgacct gtaatgaact tatcaaaacg
      841 tatttcagca gaaaacaaaa aaaattggcg cagctggcgt agataagttg tattaatggt
      901 gagactttcc catagataca actttttaga gtgcatttct aaagcttgta tctatgctag
      961 acatgaacat tgactgccgc atagattaga atctatgcgg ttttttgtgt aaagacaatg
     1021 accgctttgg ccattgtctt tttttgtaga ctggatactt gcctgattat aataaataaa
     1081 aagattgact ttgcaggagg aaaaaaatga aaaacaaacg attaataaca gttgtagtaa
     1141 ttattttagt ttatttagca ggtgcattta tttatggaaa agcctcaggc gaaaaagaaa
     1201 gtacttcgac gaaccagaca aaaaaaacaa cagttgttgg ggtattgcaa tacgtgagcc
     1261 atccggcatt agatgagatt tatcgaggaa tcaaagatgg tctgaaagaa gaaggattaa
     1321 aagaaggaga aaatcttgag atcaaatttc aaaatggaca agccgatcag agcaagctag
     1381 ccacaatgag tcaacagcta gtacaatctg atccagatgc cttgattgga atcgcaacac
     1441 ctgccgctca atcattagca aacacgactt catcgatccc agttgtgtta ggtgctgtaa
     1501 cggatcctgt gggggctgga ttagtcgctt ctttagagaa acctggtggt aatgtaacag
     1561 gtgtttctga tcagccgcct gttacttcac aaatcaagct tgcttctgat ttgttgccaa
     1621 atgcaaaaaa agtcggaatc ttgtatgctt cttcagagga taattcaaaa taccaagtag
     1681 cacaagcaga agaagctgca aaaaaagaag ggttagaatc agtaaaatat gcggtgcctt
     1741 ccactaatga gattgcacaa acggttcaag tgatgagccg acaagtcgat tttatctatg
     1801 ttccattaga taataccatt gccaatgcga tgcaaacagt ggtaaaagaa gcaaacaaag
     1861 caaatatccc cgtcattcca tctgtggata caatggtgga acaaggtgga ctagcaacaa
     1921 tcgggatcaa tcaatatcaa ttagggcttc aaagcggtaa gatggcggca gaacttgcga
     1981 gtggaaaaga aaaaccggaa acgacgcctg tttatacatt tgatcaaggg gatacagtga
     2041 tcaatcaatc tcaagctgat cgcttaggaa tcattgttcc ccaatcgatg aaggaaaaag
     2101 ccaaaatcat tacagatgac tcgcagcaag aaacatctaa ggaggatgac aaatgatcgt
     2161 atcagctatt tcacaaggca tgctttgggc aatattagga ttagggattt tcatgactta
     2221 tcggatctta gactttcctg atatgacgac agaagggtcc ttcccattag gtgctgctgt
     2281 ctgtgtgaca gctattactc atggggtagc gccgattgta gctacattat taggcgtagg
     2341 tgctggcatg atagcaggac tcgttacggg gttactttat acaaaaggaa agataccggt
     2401 tattttagca gggattttag tgatgtcagg attgaactca gttattttgt ttgtgatgcg
     2461 aacaccaaat ctttctttat tgaatcatcc gattctacaa gacagcttcc atcgctttgg
     2521 gttacctgat tactttgaca cagtccttct tggcttcatc tctttgggca tcttgattgc
     2581 tgtactgcta ttcttcttca atacagattt gggtcaaggc tatattgcga caggagacaa
     2641 cgaaacgatg gctcggtcgt tagggataaa aaccgatcgt atgaaaattt taggtttaac
     2701 tttgtcgaac ggtgtcattg cattatccgg tgcgctgatt gcccagaacg acggatatgc
     2761 agatgtaaat aaagggattg gcgtaatcgt catcggtctt gcttccatca tcatcggtga
     2821 agtgatcttc caagaattga cgctagcaga aagattgatt gctattgttg tcggcagtat
     2881 catttatcag ctattgattt tagtagtaat caaactaggg tttgacacga cttatctgaa
     2941 gttgttctcc gctatcatct tagctatttg tctgatgatc ccgcaattga agaaagcact
     3001 gaacttaaaa acgggttttg agaaggaggc atagtaatga ctgatatatt gacaatcaaa
     3061 aatggcagaa aagtcgtaaa caatggaatg aatgaagaga aagtactatt ggatgaaatt
     3121 aaccttacaa tcagagaagg ggacttcatc actgtccttg gcgggaatgg tgctggaaaa
     3181 agcacactgt tcaatacgat cgctggtacg cttcaactca gtcaaggatc gatctctttt
     3241 aaagatcagc tgatcacaaa agattcagaa gaaaaaagag cacgattcct ttctcgagtt
     3301 ttccaagacc ccaagatggg aacggctcct cggatgacag tagcagaaaa tttgctactt
     3361 gcacaaaaaa gaggtcaaaa acggaaattc cgtttacgta acttgaaaaa tcaaaaagaa
     3421 gattttttca gactatgtca agaagtcggt aatggcctag agcaacactt ggatactcca
     3481 gcgggtgaat tatctggtgg tcaacgccaa gcattaagct tgctgatggc gacgatcaca
     3541 gctcctgagt tactattatt agatgaacat actgcagctt tagatcctaa aacagctaaa
     3601 gcattaatgc gattaacaaa tcagcggatc aatgaacaaa aattgacttg tctcatgatc
     3661 acgcatcgaa tggaagacgc cttgaaatac ggaaatcgtc tgatcgtact ccaaaaaggg
     3721 aaaatcgttc aagatatttc tgaaaaagaa aagcaacatt tgacaatggg cgaccttttg
     3781 cagttctttg aagaagtagt ggattgattt cgacagaaaa attcctttca gtagaaggac
     3841 ttgaaaactc attgacatct tcctttgatt catcctatac ttaaaacaat aaacaattaa
     3901 acatatttgg gtgttttgta ggatcacgta gtcaatgatt ttaacaatta aatagaatat
     3961 tctttgctct gacaagtaaa cgatgagaaa agaatttgct actttgccac ctagacgttt
     4021 cgtacttttt cgtatcaaac gctaagtggc tttttttatt gaagtaagaa caaaggagga
     4081 ataagatgat ttctggacaa accaaattag ctgggctctt tgctgatccg gcttctcaca
     4141 gtttatcccc attgatgcac aatactgctt ttgaagcaaa caacatcgat gcggtgtatt
     4201 tagctttcca agtaaatcca atgaatttga agcaagcagt cgaaagtatt cgaacttttg
     4261 atatgttagg tgtaaatctt tcgatgccga ataaaacagc ggttattcct tatctggatg
     4321 aggtaagcca ggaagcgcaa ttgatcggag cagtgaatac gatcgtgcac gaaaagggtc
     4381 gtttgattgg ctataatacc gatggtgcgg gcttcatgca atccgtgcaa gaagctggga
     4441 tttcgatcaa aaagaaaaaa atgactctac tgggagctgg aggtgcagca aaggcagtca
     4501 ctgttcaagc tgcgttagac ggcgctgagg aaatcgtagt ttataaacga aacaaccaaa
     4561 cattcgctca agtaaaagaa acattcgaac aactcagcta tcgaacttct tgtaagataa
     4621 aagttcgtga ctttgccgat acgcatcaat taagaaaaga cttgaaagaa agctgtcttc
     4681 tagtcaatgc aacagatatc gggatgggaa agaaaatcaa tcagtcaccg ctcttagata
     4741 taagcatgat gcatgagaat ctagcggttt ttgatttgat ttatgcacct agagaaacac
     4801 gtttattaaa agaagcaaaa aaagtaggag caaaaggata caatggactt ggcatgttga
     4861 tctaccaagg agcaatcgcg tttgaattat ggacaaagga aaagatgccg atccatgtga
     4921 ttgaaaagct gtttgattaa aaaaggataa tagataaaga tcttttattc tcgcataaac
     4981 ggtctcaaga aaagtaatcc tttatgtatc gaagcattta tttcgttatt ttttattaaa
     5041 ttatcaaaaa atgataggct tttgtcgatt ggttatcgta tcctttattt atcagtaaga
     5101 aacgaggagg aaccacaatg agtcggatgg atcgctataa ggacatccat aagaaggcga
     5161 aacctctgaa gcgggatacg gggagtattt ttgctagaag agaacgaaaa cgaacgcgta
     5221 tggaaaatga ggaagatgct acccgtattt atgaaagaga gcagcattca tttgaacatt
     5281 tgaaccaata cgagcaacag atatacagag atgcaccaag agcagaagaa caacaaaaaa
     5341 ataaaaaatt tttcaatcgg caaaagaaga acaaaccgtt aaaacctcga agaaagcgat
     5401 cgtggaaaaa aatcattcta tcgattttgc ttgttttgat cctttattca ggtatctcat
     5461 tttttattgg taaatatgta gctgaacatg acacaagctt agaggcagcg acttcagaaa
     5521 cctttcatgg gcaaaaagcg acgaatggtg cgcataatat tttgatcctt ggaagtgata
     5581 cacgcggaga agatgccggg cgagccgata cgatcatggt cttacagttg gatggtcctt
     5641 cccataagcc gaaactgatt tcttttatgc gtgacagctt cgttacgatc ccaggggtag
     5701 gacaaaataa gatcaattca gcttatgcat acggaggagc cgatctagtg cgtcaaactt
     5761 tagtagaaaa ttttggaatc gattgtcaat actatgcgaa agtcgatttc aaatcgtttg
     5821 aaaaagtgat cgatgcctta ttcatgaacg gagtgaagat cgatgcagaa aaagatctga
     5881 atctggatgg tgtagatatt aaaaaagggg tccagaagat ggatggacat gttcttttgc
     5941 agtacgcacg tttccgaatg gatgaacaag gagactttgg ccgtgtcaga cgccaacagc
     6001 aagtaatgaa cgctattttc agccaattga agaatccatt gaatctgatc cgtgcacctt
     6061 atgcagctgg taaagcttta ggatatacat ccacagatgt cactgcttgg ttcttgacga
     6121 aaaacctctt ttcgattgca cgaggagctg gtggcattga tcgaataagt gtgccagtag
     6181 acggttcgtg gaattatggg caaagtgatt atgctggcag tattcttgaa attgataatc
     6241 aaatgaatca atctgctatt acagattttt tgaataaatg atcataaaaa agatcaagaa
     6301 gaagctgcgc aaggcttttg tcatgaatca atcaaacgat tcactcgtaa aaaacgcttt
     6361 cttatggtag atttaaccaa gagaggagct gtttacattg gatatctatc tgaacttcaa
     6421 aaatgagtcg cgtgaagcca tcgcttttta tgaaaaagtt tttcagactg aagcatcagg
     6481 tatcaccaca tacggtgaaa tgcctggaat agaacaaatg aacttgccag aagaagcaaa
     6541 aaatctaatc acgaatgcac ggctgaacat ttatgataca ttagttatgt ttgcagatac
     6601 gccagaagga attggtcctg aattagttgt gggaaataat gtttctttag tcatccagac
     6661 aagaaatgaa gaagaaacga agcgcctatt tgaaagctta gctgagggtg gtaagattga
     6721 gatgccactg gatgctgttc cgtgggctca gttgtatggg atggtaactg atcgatttgg
     6781 catcaactgg cagattaacc aagagtgaca gctaaagatg aatattttct ggaaacatca
     6841 agcagcaaac ggatcatcgt ttgtttgctt gatgtttttg tgtctatttc gactatacgg
     6901 tatctttttt ttattgccag atgcgaaaat atgttccata atagagaagt ccgcaaaaaa
     6961 ttaagtaacg gaggtcagaa gatgaagacg gtgatactag ctgaaaaacc ttcacaagca
     7021 aaagcctatg ccgaaacctt ccaacagcaa aagcggcatg aagggtatta tgaaatcagc
     7081 gatccattgt ttgctggtga agtaaccatc acttatggtt ttggacattt ggtagatatg
     7141 gttgctccag gagcttatga agagcgttgg gcaaaatggt ctttagaaaa tttgcctatt
     7201 ttcccagaaa ccttccgtta cgaagttcca atggacaaac gtgcacaatt ttcgatcgta
     7261 aaacgagaat tgcagtcagc cgataccatc attattgcaa cagatggtga tcgagaaggt
     7321 gaagccatcg cgtggtcgat tattcgacaa gcaaacgcat tttctaagga aaagaactat
     7381 ttacgtttat ggatcaattc tcttgaaaaa gaagcaatct atgaaggttt taagaatctc
     7441 caacctggaa agaactattt tccaaaatat aaagaagcgc aagcaaggca gaacgctgat
     7501 tggctgattg gaatgaatgg aagtccatta tatagcttgc tacttcaacg aaaagggatt
     7561 gatggcagtt tttctcttgg tcgtgtacaa acaccgacac tctatatgat ttatcagctg
     7621 caagaagaaa tcaaacactt caaaaaagaa acgtactttg aaggagaagg tttaattacg
     7681 acaaacaaag ggcagttttc tggaaaaatc gtaccaaaaa aagcatttaa aacccaagaa
     7741 gagttaacga aggaaataga aaaacttgga gcgcatttag gtaagcaaaa cggacggatt
     7801 cttgaagtta cgaaaaagga aaagaggttg catagtccac gtttattttc gctatctagt
     7861 ttgcagacaa agatgaatca gctaatgaaa gcaagtgcca aagctacact tgatgctgct
     7921 caaggattgt acgaaagcaa gtttctaagc tatccaagaa cggattcctt ttacattaca
     7981 gaaaatgagc atcagtatct ggttaaacat ctgcaaaatt ataaaaaatt tttaggaata
     8041 gaagaagtac agacaactga gatcaaagca aagaaacgat atgtcgatgc gaaaaaagtt
     8101 caagaacatc atgcaattat tccgacaaag acgattccga ctcctgcacg ctttgcgaag
     8161 ctttccaaat tacagcaagc aatctatttg caagttttgc gcactactgt ggctatgttt
     8221 gctgcagatt atatctacga agagacgacc gtaatgacgg gcgtacagca attaaagcta
     8281 aaaagcatcg gaaagatccc attacagcaa ggttggcagg aaatcttacg catcaagtca
     8341 aaaaagaaag aagctcagac tcttcctcct atcgtagaaa atgaagaagc agaagtagaa
     8401 ctgaaaagta tggagaaaga aacacaacct ccaaaaccct ataccgaagg aacgttgatc
     8461 acagcaatga aaactgcggg aaaaacgctg gataatgatg aagcgcaaga aattctcaaa
     8521 gaagtagaag gaatagggac agaagctaca cgagccaata tcattgaaaa tcttaagcag
     8581 aagcattaca tcgaagtcaa taaaaacgaa ataactgtta cgccaaaagg aatcactctt
     8641 tgtaaggcag tagccaatga accattactg acgagcgcag aaatgactgc gcgctgggaa
     8701 gggtacttga gaaaaattgg taaacaagag gggacaccat ctgttttttt agagaatatc
     8761 aaaaaattca tcctacattt attggcagaa gttcctaatc aaatcgacaa ggtagacttt
     8821 tcagatgaga ttagcgggac acgtcagata aaagcgatgg agaagaaaaa cgatcaatta
     8881 ggaagatgtc caaaatgtaa aaagggaata gtcatgcttt atcctaaaat cgctacatgc
     8941 ttgaatccgg aatgcgactt caaattgtgg ccaacagtag ctaaaaagaa gctgactaaa
     9001 acgaatctca gagatttgct ttcaaaagga aagacaagta aagttgtcaa aggttttact
     9061 ggtaaaaaag ggaaattcga tgcagtttta gtattaaaag aagatatgac aatcggtttt
     9121 tcttttccat ggatcgaaaa cagtggaaca aaagcagttg atggaaacaa agaaacatca
     9181 agaaaaaata atgaaaacga agtagagtaa atgaaaacaa tgaaatagcg gaatatttat
     9241 tccgaaaagt gagaatataa ataccaataa aactaaaaaa tatcagtgaa tcaagcaaaa
     9301 acgttggggt aggctgattt tatatagata gcaaggagtt tttttatttg aaaaaagtgc
     9361 attcattttt aaattatctt atgggagcaa tcacgattgt ggctgtgtac caagcatttc
     9421 taaagtatcc tgattacggg acgaagttgt tgtcattgac gcacaatcaa acagcatatt
     9481 caccaacgtt gattttatcg actttgactg caggagctaa aagcgctact tatttttttc
     9541 ataaaacgac aagcatgcta aagcgaaaga aacagcgaaa acaattgttg gtggtggtag
     9601 cggctatgat cattatttat tttctaccag ttattacaca agtatttcat caatattttg
     9661 gttaagaata cgagagtttg tgacaaaagt catgtcacaa acttttttct ttgtcatttt
     9721 ttcgtaagaa aaagcaaaat aaaagtatat acattgatta aaagtatata cttggatata
     9781 atgtacttac tatagaatga gaatggtata gagggtggcg aaatatgaaa aaaatgaaaa
     9841 agtataaaat tagaaaatct ggcaatagcg atgtaacaac tatcccacca gaagtaaaag
     9901 aattcatggg tgtgcagaca ggtgacgcaa tcagttatgt ttttcaatct gatggttctg
     9961 tacgaatgat caaagcacaa gaagaacctg atattgattc attagttgat tcgatcatga
    10021 atcaatatga agacgcgtta aaagatttgg ttgatttatg aggtatcttt cgactaaaga
    10081 aattatcaaa atcaacgcga aagttatttt acgtcactcg ccaggcgaaa tgatcggtgt
    10141 aaaagatgca aatgcattag atatggccgt caaacagcct tcacaagcag tattcaatca
    10201 agaactctat cctgaaatct atgaaaaagc ggcgatttta gcaattaatt tagctaaaaa
    10261 acatcctttt cataatggca ataaacgaac tgctcttgtt gccatgttgt tgtttcttca
    10321 attgaataat tgtccagttg ctttttctcg tcaagaagct gttgatttta tcataatgat
    10381 taccactagt tcattggatt tcgattcact aaagtccaag ataaccagtt atttacgaca
    10441 aaccgcaata aaatgaacga attaaaaact ttatttctca attagatcag catgtcatta
    10501 aggaatatgc tgattttttt atgtttaatc atacaaaata gttttttcat aaaaatatgg
    10561 aaaatatgga ttaattttga aataattgat ttaaaaggaa tacaaaagag tgaatagtag
    10621 gaaatagtgg tttagaacta gtgggctgat tttttatata ttttagttta cataatatat
    10681 attatacaaa gtagatttaa aaaatgataa acctctctcg aacggttttt tatcaaaaat
    10741 cgtcattttt ccatcaaaat ctgcttatgc aaaattataa aaaaattttg cagtttttct
    10801 tacttttttt gtcgtttaat tgaatgataa aaaccagttt ctttattcag ttaatcaaat
    10861 atgaacgaat tagatatgaa tcattgtatt tgccgttgcg gaaggatttt ttaattaacc
    10921 acagataaac attgataacg attcgcttat tgtaatcaac agattaaatt tcatatgttc
    10981 atatgtacgg atacattttc ggaccgatta attttaacca ttctatttat ttgcttacct
    11041 attagatatc aataaaaaac tgcttaacag ctatttcagc tgttaagcag ttttaggatt
    11101 tttagttcat attcattgtt tcttataata cagtgttcaa tacttctctt aaagcacttg
    11161 ttgatttgct gaacattgct ttttcttctt cgttgattga taattcaaca acttcacgaa
    11221 caccattttc gtcaacgatt gatggcacac ctgtaaagat atctttttcg tcgtattcac
    11281 cagttaaata agcagataca ggcaatacag cttgttcgtt attcaagata gcttttacga
    11341 tacgtgcagt actcatacca ataccatagt aagttgcttt tttacgatca atgatctcat
    11401 aagcagcatt acggacttta tcagcaatca catctaattc atcttgggca atacgatggt
    11461 ctttttctac aatttcaaac actggtttac caccgacagt tgtatgtgac catgcagcaa
    11521 cttctgaatc accatgttca cctaagatat agccgtggac gctgcgtggg tcaactttta
    11581 atttcaatgc gatttcttta cggaaacgag ttgtatccaa tgttgttcca gtaccgataa
    11641 cacgtgatgt tggcagacca gattcgttcc aagcgatata tgtcaaaata tctactgggt
    11701 ttgaagcaac aacgataata ccgtcgaatc ctgatcccat gatttctttt acgatttggc
    11761 gcatgattga cgcatttgtt ttaactaaat ctaaacgaga ttgaccaggt ttttggttga
    11821 taccagctgt gataacaacg atatcagcat ctttacattc ttcatagcca cctgaccata
    11881 cagccacatt ttcatcgccc caagccatac catctaaaag gtccaatgct tccccttctg
    11941 ctttttcttg attcacatcg atcaatacta attcattaga gattccttgg ttgatcattg
    12001 cataagcgat acttgttcca acaaaacctg taccgacgat tactacttta cgacttgttt
    12061 ttttcatgaa taaacagctc cttttcataa ctatttgtta ctttcatgaa aagtatagtc
    12121 ttgtttattc attttatcaa catgttaatt ataatagttg ttattataat ttttgatgga
    12181 aacgaattcc tgaatacgca taacagataa atgacaaatg tttacaccta tatcccctga
    12241 taatacaacc aaaagtttag aactgaaaat aaatccaaaa aaattcgctg caacgatata
    12301 ataagacagc aatcgcacct aaaacaattt tccttcatat gctttagtga aagattttct
    12361 tcttaatgtt tatttctcca ttcattggga gtacatgttg aatacttctt gaataatttg
    12421 aataaagaag tcgtttgttt atatccgata cgattagcga tttcttccaa cgaaaaactc
    12481 gtttcttgaa tcagttccaa cgcaaagtcg aattttttct ttagaaccag ttcttgaaag
    12541 gaagcatcaa aatacatttt caatttatta ctaagataga ccggattgta gccaaaatga
    12601 gctgctgttt cttttaacgt acaagaagta aaatgcttat cgatataatc taatactcta
    12661 agcatctcat tttctgcgca tccatctgct gatgaaaagc tttgttgttc taataaatga
    12721 gtcaattcga tcagtaatag tgatgtatag agatttaacg aacggatctt atgactgtat
    12781 gtatcaaaat aaatcaacag catattttca atcaaatgcg tcaaacgact tgtttttccg
    12841 ccgcgaaaat gaatgaattg tgtatgttcc cctttttctt ttgatgcatt tatcaaaaaa
    12901 gaagaaagta gattatttgt gcttgccaaa tgattcaata tctctgtaga taaggtttct
    12961 tcttttaata agatgttgat taaaatatcc tcttgccctg tgtattcgat tctttgagta
    13021 gcttctttat caatgatcac cacgtcactt tcttccatct ctatcctttc tccattaata
    13081 atttgtaaac atgtaccgct atacatataa ttgatttcaa caaaatcatg tgtatgctcg
    13141 ggaacttccg catatcgacg gtgtttactg atatgaatat ttccctgttg aaatagatcc
    13201 cctcggtgga tttttggcgg tgtctgaaga tggtaagcta agtttaaatc attgatattc
    13261 attccttgtt cacgctgcag agtttcgatt gattcttcgt tacgcaaaaa aaatgtctaa
    13321 ttcagctagt tccaattgac tccctccttt ttgtaagcgg tttctttcgc ttattagttc
    13381 acgctgtact gctattatat gcaaagctat ttttggtttc ataaagactt tctatggttg
    13441 ggacatgaac ttcctgtgat tccgctattg agagaataac cacttcatac tatatttttg
    13501 ataagcgctt acaaaaatga aaggaacatg cttatgaata aaaagatgat gaaattttct
    13561 ctgctgtcag tctctcttat tttgacttct gctggtgcag tcacgtctgc aattcccagt
    13621 atgtcagcta cttatgccac gcgttcttta tctgctgttg aattattaac gactgctccc
    13681 tcttttatgg tcactatttt tgttttgatt agtagtttta ttgctaggaa aatcggacaa
    13741 aaacaaactg tgatcatcgg attagtgatt gcatcgattt gtggtatcct ccccctcttc
    13801 tcacaaagtt acagtattgt cttagcttca agagctggac taggtattgg ctttggattg
    13861 atcaattctt tggcagtcag catgattgct gccttttatc acggagatga acgagcctct
    13921 atgattggtt ttcaaagtgc atttcaagga tttggtgcag ctttaatgac atttgttgca
    13981 ggacagctag tacagttcgg ttggcaatat acctttttag tctacgccat cagcttacct
    14041 attcttgtct tgtttgtttt gtttgttcct acacctgaaa caactgaact tcaatcgcat
    14101 ggcacagccc caacaagaca agtaatcaaa acgaatccta aaatgattag ttatggtatt
    14161 tttctcttgc tggtcatcgt ggtatataat gctgtatcga ttaaattagc cacagtcctg
    14221 acgacttatt ctctaggaaa cgaaactaat gcagcgaata tcttaacaat catgcaattg
    14281 gcaagtatgg ctgccggagt ttgttttggc tggcttcaga caaaagcaca tcgctatatg
    14341 cttacacttt ctttactact gatgggaatc ggctttgtat tgattgccac tgtgataaac
    14401 ctgtatgtga ttgggtttgg tgcgatccta acaggaattt ctttttcgtt attcattcct
    14461 tacttattca accaagtaag tatccaagcg cccaagtacg cggagagttt caatacttca
    14521 atcttattgg ttggcgctaa tttaggtact ttcattgcac catatggttt gctctttctc
    14581 tcttttgctt ctcttgggag taaaacactt gctgttttcg tcaatggcag tatcttgctg
    14641 ttgattagcg cgcttattag ccttctagta gtacacagga cgaatagaaa gacagtgata
    14701 agagtagatg aagaaataaa agaacaattg acaacaaaat aaatttgatg gaggtcgtgt
    14761 aaaatgacaa atgaaaaaca taaagataga tggctttggt atcctggaga ctttgagatc
    14821 cgccatggac tgctacaaaa tttccaacgg gaagaacgag gttttgactg gccagcgtac
    14881 tggtacatgg atgattgcca tcggaacgtc aagtttaaga gatattactt tcttgatcaa
    14941 ccttccatgt ttaaagtgac gatccaagga gttgggtatg tagaaattaa tggacaaaaa
    15001 catccatgtg gaaaatggct gacttgtcca gctggtaaag caaaaattcg tatctttgta
    15061 ggacatacat cagggctacc agcgatgttt atcgagggag acgaagtaaa atcagatatt
    15121 ggctggacag caagtaattt tattgaagaa tatccagctg gctggagtcc gctttatgtc
    15181 gatatcgcaa aagatccaaa tcaaatctat tatcaaaaag aatgcgtcca tccagtcact
    15241 gaaacggaga ttggcggagg aatcttattc gattttgggc gagcagtgaa tggctgtgta
    15301 gaactaatat ctctggatga ccatatcgaa tctatcactc tatgttatgg agagtccgat
    15361 gtagaagcta tggatatcga ttattgctac tataagcaaa taggaatgac aagaaaaatg
    15421 aaagctcgta aacgcgcttt tcgctatttg tttataccag aggtttctac tggaatggtt
    15481 caacttcaag tttttcatga atttttatct ctttcgaaac aagctgcttt ttcaagcgat
    15541 tcttctttac tgaatcagat ctggtcagta tcagaagaag ccttcaagtt atgtagtgat
    15601 ttgtttttta tcgacggtat caaacgagat cgctggattt ggtctggaga tgcgtatcaa
    15661 tcattcatga tcaatcaata tctttttttt gacgaggaaa tcaataaacg aacgatatta
    15721 gcattaagag gacaaaatga aatcaagcag catatgaata ctatcgttga ctattcgatc
    15781 ttgtggttga ttggtatcga aaaccactat atgatgacga aagactatga atttttacgc
    15841 atcgtctacc ctaagatgca atcattaatg agatacttga tggagcaaac gaatgaatta
    15901 gggtttattt atgggagagc aaaagattgg atatttattg attggtctga aatggataaa
    15961 gaaggaacgc ttgctgcaga acaagtctta ttactgaaag cctatcattc catgatcact
    16021 tgcggagata tcttagctga aacatatgga gagaacgaaa attatcatac tcatctctat
    16081 caagaaaaat atcaactatt gaaacaaaac ctatttgact acttttggga tgaagaactt
    16141 ggcgctttta tcgattgcta tgaatctggg agaagaaatg tgacgcgtca tgcgaatatt
    16201 ttcgctgttt tattcgattt tgctaacaaa gaccaacagc aatcgatctt aaagaatgtc
    16261 ttattgaatg acactatcac acagattact actccatatt tcaaattcta tgaacaagat
    16321 gctttatgca aactcggaca gacgaatatc gtctaccaaa cgattcttga ttattgggga
    16381 gggatgttat ctcatgatgc ggtaactttc tgggaagaat acgaccctac tcaaacagga
    16441 aatgaaaagt acagtatgta tggagatcct tatggaaaaa gcttatgcca tgcatgggga
    16501 gcaagcccaa tctatctttt aggacgctat tttatcggtt tgtatccaac aaagccaggt
    16561 tatgaagaat ttatgataca acctaatcta gattcatttg aaacactgaa ttgtacgcta
    16621 cctatcaaag atggaaagat ttcgcttgaa aaaacaaaag ataagatcgt gattacttct
    16681 gatagaacag gcggaacagt gaaaatgaat ggtaaaagtt atcctcttct agcaaaacag
    16741 ccacttgtct taacaagcta ttcaaaaata aatgcataaa acaaaaaact gcttgcgaca
    16801 tatcagaaga ctttaaatct tcttctgata ttgtccaagc aatttttatt ttgaagtttg
    16861 cttaattctg ttctttagaa acaatgtttg ttctttttcc ggcaaaaaga aagctagata
    16921 atacgacaag taaaaagaaa gcgatgattc caactgtcaa ggctatttga ccgtattctc
    16981 ctagtttccc aagtacaagt cctggtacta gataatcagt atcggcaaat gtagaagaag
    17041 cgattttaag atctcctaat actggaagga taaataatgg cagccaacta atcaataagc
    17101 tattgaaagc agaacctaat accgcccctc ttctaccgcc agtcgagttg ccgaagacac
    17161 cagaagcagc tccgcagaag aaatgtccta ctaccccagg aatgataact gtagtttgca
    17221 agcctatcat agcaaacatg gatagtgttc ctacaaagaa gctaacaaaa aagccaatta
    17281 atacagcatt aggtgcatat ggaaaaacga taggaacatc taatgctggt ttagaatcgg
    17341 gtacgagttt tttagcaatc ccttggaatg ctggaacgat ttctgccaac accattcgaa
    17401 ccccttgaag gacgataaca aacccagctg tgaatgttcc agcttggatc agtgcaaaga
    17461 ttacagcgtt gtctccattg cttagttctc tttcaacaaa tccaggacca gctaacaaag
    17521 caagtgcgac atatacgatc gacatcaaga gcatgatcga tacagtagaa tctcgcaaaa
    17581 agctgaaact tttaggaatc tttatgtcct ctgtagaacg gtctttgttt ccaaaaaact
    17641 ttccgatcca tccactagaa gcataaccga tatttccggt atgccctaac gcaacttgat
    17701 tgtttccagt gatgttcttc ataaacggtt gacaaagagc aggcgtaata gttaatagtg
    17761 ttccttcgaa gaccccgcct aataagatca tccacaaatt tgcagtaaac cccgcgctta
    17821 ctaaaatgac tgctgttaga caagaaacat aaagcattgc ttgacctgta agaaaaatga
    17881 atttatatct tgtgaatcta gcaagtaaaa tattcacgat catccctact agcatgatca
    17941 aagcagtagg tgtaccgtat tgttgcaaag caatcgccac tactgcttca ttgctaggaa
    18001 ctactccttg agtatgcaga gctgtttgga acatcgaagc aaaaggggtt agtgaattac
    18061 tgattaaacc agcaccgccg atcagtacta ggaatccgac aaatgttttg atagttcctt
    18121 ggatcacttc tgaaaatttc ttcttctgaa gaacgagacc aagcagtgca atcaaagaaa
    18181 cgaggatgga gggctgactg acgattgaca caaacaaatt caacaattta tccattgata
    18241 gttcctccct tgaatcattt ttattctttt gacaagatct tcgttacttt ttcttttact
    18301 tcttcgctgt caatgatcga ttgcaaaggt acgagctttt catcaggtat agaagttagc
    18361 gtatctttca aagaatgctc aatgaagaaa taatcagcca tatcgctaga tacacttcca
    18421 acatccgtat gacttacttc aaactcgtcc acatctgctc caagatctgc aagtgcttgt
    18481 ttgatgttca tctctaccat aaaacttgtt cctaatccac tttgacatac tgcaaaaatt
    18541 ttcatatcat tcgtctcctt ttcttatgat cgctaatatt tcttcttttg ttgatgcgtg
    18601 taataaatct tgaagatttt gtttattaga aagtagcttt gttaaatttg ccaaagcccg
    18661 aagatgtgcc tcattatcga tagcagctaa acagatgaac aaactaatgg gatgggctgg
    18721 attatcaagc agatccacag gttgttgaag tttcagcaaa gacatcccta cttcgtttac
    18781 gccatcttct ggacgagcat gaggtaatgc gatgtgatcg ccaatatgga taaacgcacc
    18841 atactgctcc acgcgctcga tcatagcttt gatataactt tcttctattt tattttctga
    18901 taatagcggc tgtgcggcaa atgtgattgc ttcttgccag ttttttggtt gatccgataa
    18961 ttggatcatt tcttctgtta ataattcaga tagcatagga cgttgatcct ccttcttttc
    19021 taaaagtttg ttcattttac gatttaatac ttgatagagc ttttcttcgt ctacgccttc
    19081 ttttaattcg atataaggca gtagcgccga caacaattct tgggcagaag gcattgaaaa
    19141 tcctggtatc agccaatctc tttgtacttg attgatcagc tgattttttt ccaagtcagt
    19201 catgattgga tgcagaacat agagagactt tttcttatca gtaagtgtga gaggtacagt
    19261 agaaaaaata atatcgtaag aagtttcgtc aacctcgtgt aagcggtcag ctgaattagt
    19321 ctctgtaaaa aagatcatcg ggaataattg ctgaagttca ctttttaaga tcaatgaaga
    19381 gctaatgcca cttggacaga cgatcacggc tcttattttt ctatttcttt cttctgcgtc
    19441 cgcttttctg atctctccgc caaatagtat agtgaaaaaa ccaatctctt cttcagggat
    19501 gctcttccct attcgtcttt ctaacggaag taatgctttt cttgtcattt cgtagatgga
    19561 agcatattga tgcttaattt gatcgatcat cacattaggt aaataaaaag aataggaaat
    19621 acgaaaatag gcagggacca agtgataaaa gacattcatc aataattcac gaaacgaagc
    19681 aaattctacg gccatcagga attccatgcg atggatgact tctgaagaac attccagcaa
    19741 aaaatcaagt gcaggctcct ggacatctcc ttcaacgatc gatgctaagc aaagagagaa
    19801 aaatataatc tccgaatttt gatgttcgga atagccaagg ccagtcaata cttgtcgact
    19861 aatgtcagtg actgcaagag aagccaacag ttcagcatct tttaccagtt ccatggatgt
    19921 ttttccaatt cgaatggttg tcaaactcaa ataataagct aattcatcca ttcgatttgg
    19981 tgcgaatcga agatctgata gtgaaatcgt tttatctagc aaatctctaa ctttggcgta
    20041 ataatcaatg gaaagggttg cggttaaata cgtgagccca aatcttccag caagtgactg
    20101 catcaaacga gcagtgcgat tttttgcttc tcttcttaat attgcttctg accctagcag
    20161 cctaaaacca gttttcctag tatacgacag ctgacaatct tccacttcta attcatttct
    20221 tatctttttg atatctgaca ggactgtccc tttagaaacc tgaagaaaat cttgaaaatg
    20281 aaaaacagaa acagacgttg cagtcgaata aaccatcaaa taaagaagat ctcttcgctc
    20341 ttgttcggta tacacagctt caaatcgagt aatatccaaa aatttttctg cccagtcgat
    20401 tgctcggaat ttctttatac ggatacgggt atcatccaca tattcggcaa aaggagttaa
    20461 ttgtttgatc gcctcgcttg tatttacttc gatgatctct gctgcttttt ctagactgat
    20521 ttctcttggt gttttcagga gataactaat tttgtagttc acagcgctgt tcacctccta
    20581 cttatattct agtatggtag cgcttttaaa tcgaggggtg tttggtacaa cttacagttg
    20641 gatttttttt acgactgtac cgaacgattt ctatcgaatg gatacagaaa aaaagcaggt
    20701 gaccaaatgt ctcctgcttt tatgaattga tttcgtccga tcaatgatga tcatgtttat
    20761 tttttgaggt cagttcttca aatttttctt tgacatcttc aaccgctttt tcgatatctt
    20821 tttcaaagtg attgggctca ttaggctttg tttcctcttc tacagaattt gaaccagata
    20881 aagctgtttc tttattttct gtttcaccag agtttgtgcc agctaatgat tcttctttgt
    20941 cttctgtttc accagaatta gttcctgcta aagccacttc ttcttctgtt ttaggggcca
    21001 ttgaacctct taatcgtttg tgtttttcac cgtcataatt tgtcatgttg gttcctccta
    21061 gtagttctat actttttcat cgtacaataa gacagtttat gcgtcaaaaa acaaacccga
    21121 ttcttacaaa tatgtcatat ttttccttct gattcttgaa tgcttttgat tccttcttcc
    21181 aaaattttca tttgtaagat tgtttcttca tctttgatga ctttttctgc gccattaact
    21241 aatgtctcgt aaatcccttc gtagacacgg ctgtaatcac caacctcgga aattactttt
    21301 tcttcatgat aactcccttg ttcatctata taggtcaata caccataatg ttcgggcaaa
    21361 tcgataccaa agtcttcatg atcaggcatg taaaacattt tcagatgttc ttcttgtcga
    21421 tcttttgttt gtttcacgaa catccctttt tttccgtaaa cgacgaaact tggacgttct
    21481 ttgatgcgga aataactgga ttttatcgaa attttcatat ttccatagaa aaaatccaga
    21541 tcgaagtaat cattcattcg tcctttccct aaaagttgac gtacatcata gctgatatca
    21601 tctggttcgc cgaaataaga aagaacttga tctactgtat gacaagcatg tccatataaa
    21661 tagctgttcg cagtagaaaa ttcatgcgta ttttctggta cttccggtct gaaataatca
    21721 taatgcattt ctacttctaa aatatcccct aattttccgc tttcgattac tttttggact
    21781 gtcaagaagt cagaatcgaa ccgtctgttt tggtaacatt ggataaatag acctttttct
    21841 tttgctaatg caaataactc ttctgcttcc tttgacgttt ctgcaaaagg tttctctact
    21901 agtacattct taccatgttc gagtgccatt tttccatatt cataatgaaa ttgactaggt
    21961 gtagtgatga caactaattg gatctcagga tcatcccaaa gatcagacag ctgatcagta
    22021 tattcgatgt cttcgaatgt tttccacact ggttcagatg gggaaaaaat ttttttgata
    22081 ttgattttgt tcgtaagttt tcttgaaaaa ggcaaatgat agcgatttgt actctttcca
    22141 ttgccaagat aagcgattgt aagcatgagt ggtgcctcct tttattgatg ttttcagtat
    22201 atcctagaaa agcgcagaaa gtatttataa tagctattct ggtaaaaaag ttcagaaaaa
    22261 cacttgttat cattcggttt ggtgaaatta atgttcaaag taaggataaa aatcaaaaag
    22321 atagtagcgg aaccaagtgt ttatcagtaa gatagaattt ggaggtcaga tcatgcttat
    22381 tgaagaaaaa ctaacaaaac aagagttgtt taccacgaca gagaaacgga ttgtcgatta
    22441 catccgtagg aatatcgaag ctgcagtcta catgacgatt gaagaattag caaaagctac
    22501 gtatacttcc cattcagcta tcattcgttt atgcaaaaaa atgggattca gcggatttaa
    22561 agaattccgt ttcgagctgg ggcgggaagt tcatcaattg attgctcagt tcaatcaaac
    22621 gattgatcct aattttcctt tttcaagtga agatagcact cagcaaattg caaagaaaat
    22681 ggcggattta tcgatccagt caataaaaaa agcacaattg cagattgaac atgaagattt
    22741 agatcaaatc ggtaaagtat tgaacaaggc acagcgaatc tttctttttg caaaaggtga
    22801 ttctcaaatc acggcaagga aattccagaa taaaatggtc aagttgaata agtttttgat
    22861 catggctgaa gaatacagtg attcttcttg gaatgcagcc aatttgacta gcgaggattg
    22921 cgccattttt attagctaca gcggtcgcat ccatcattat gaacgaataa tgacctattt
    22981 gaagcatgta gaggccccta ccttgctgat taccggaaat cagcattcag aaatggccaa
    23041 acaggctgat atgtgtcttg ttatatcgca ggaggaatat gattttgcta aagtagcgac
    23101 tttctcctct caaattgcct tcgattacgt attaaatacg ttattctcag tgatatattc
    23161 tcaaaatttt gaagagaata tccgcaactt gaaaaacaaa caagaattga tgcaaaaagg
    23221 ccttcttaaa gaatatcgga aaacttaaga aaagatcctc atttagtaat aagaaagata
    23281 gtgtttgata ggctctcttt gatatcatca taaaaacagg ctgaagtttt ctttttcaaa
    23341 cctcagcctg tttgtttacg gaacgattcg aatagatata ttatagaaat gaggaatagc
    23401 taacttctgt ttcttatttt gaacgattga cgaaaaagat atataagaag gaggaaaatc
    23461 agtatacatg cagctaacaa tccatacagg aaaaatcgtt tgttctcgga tactttctgt
    23521 acttcttttt gaacttcttt tgcatgataa ggaacccggt gccctctgac aagtaagcga
    23581 tgactgttga ccatataagg tgtacaagtt aggagtgtca cgaaatcctg ccctttttcg
    23641 attctcagat cttttgtatc agtcggttct accgtcttga tctgatcgac ttgataagcg
    23701 agtgtccgtc cattgatttc gatatagaaa gaatcaccta aagtcagttt cggtaagtct
    23761 gtgaacaact ttgcttgagg cagtcctcga tggctggaaa taacggcatg tgtattttct
    23821 ccccccgtag gataagacgt tccttccaat aatgaggcac ctttttctag cagcacagta
    23881 ttcgtttcat caaaaattgg caaatggaca ttgatctcag ggatcgtcaa aataccgatc
    23941 gtatgtttct caaaataggt tctatccttt ttcgcaggtt cttttttctt agtaaaggga
    24001 tctgcacctg gatttccacc ttcttttgct aattgctggt ttttctttgt catgttttct
    24061 tggattttag ccatgacttc ttcattttct ttgaccgctt gttgctgata atgagagatg
    24121 atctgctgat ccagataatt attcagcgcg tcgctaacaa atggataagc tagtatccct
    24181 attcctgaga gaagcaagaa aagcatcagc agatctagaa gtttcctttt ctttggtttc
    24241 atttgtgttc tccttgtgat gactgtttga taataaaaga aaaaggagca tttgcgtaat
    24301 ccgctgctcc tttttccaat tcttgcaaaa agactaaatc tgactgtgct tgcgtctagc
    24361 aaagtacagt ccagcaatca gtagaaggac tactcctgca ccgatataca catagattcc
    24421 cttaccgcct gttgaaggaa gtgtaccttt gtgtttattt ggtatttttt caggagaaat
    24481 caactgtcct gctgttacat aagattgttc atcgatagta aatgctacac ggtttgttaa
    24541 tggaacatat ttttctggcg ctttcgtttc ttccagatag tacgtgccat attttagacc
    24601 tgtcacatcg attaaaccgt tacttgtggt tgtaaaaacc gttgctgatt ctttcgccga
    24661 tacccagctg acggcttttg tggatgggtc gatcgataaa tatttcgctg tgtcactatc
    24721 ttgatcacga acgacgaatt ctgctccagc aagtgtttgg tctgatgtaa cgtcaccatc
    24781 tactttaaca aatcgtttgc ccccagtaac gacatcgact gacggtggtg tttgatcatt
    24841 tgtatgcccg ttatcgacat ttgcttggtt agaaaatcct ttggttggat ctgctttttc
    24901 gttcaaatgc atatagtaaa cgaatttcaa tgtaccgcca ggagttaatg aaggaatata
    24961 attcggatca actgaaaccg tgaatccgtc tgtttgctca gtgacagaat aatttactgg
    25021 gtcgatttct ttatttccat catataaggc ataagcatac gttcctgaag aatcattatc
    25081 aaatgttaaa gcagcgtcat gagtatcgat aagtttgaat gttgtgtact tgttttgcgt
    25141 tccttcttta tcagcgatac ctaatgggat attgacagaa atctcatatt gaattttttc
    25201 accgattgcg acatcttttc cattcaattg aggtgttgtt ttatcaactt tagacgtatc
    25261 atttttgatg gtcttttcta ctggtgtttg gctatttgcc aggatctcaa aaggcgtgat
    25321 tgtttgcttt tcaatcattt ccgcattatc aggagctttt acttcttcta aattatattt
    25381 tccaacttct aaatgattaa cgatcaactg gcctttttca atagatgcct cggcaaagtc
    25441 attgttgccg atgtcataag aatgaccagt aatgaaatgt ttggctttgg tttgatcagt
    25501 tgtccaagtg tacaatccat ctgtgacact ttggatgtat tttttgacgc ttggtgttcc
    25561 ttcttcttta gaaataataa attctgctcc atttagtgct tcgttttcgg cagtaccgat
    25621 ttttgtaact ttcaacgttc catcattaca gactgtattt ttagggtaga gatggatagt
    25681 atctagttct tctgtcccgt atttataaga gccatctgct tgtttgatca tctcatatac
    25741 agggaaagct aaaaccatgt ttgcggcagc tgacactccg tcttttggtt cttctttgat
    25801 cgtgtagact gcatctttcc cattttgttt tttaggtaaa gataaagtga catttccatc
    25861 agcatctgtc gttcctgaag caactggtgt accaggagtc aaagactgga ctgcttgttt
    25921 tgctgcatcc acggacgctc ctttatctcg ttgcgcataa aattcttgag tgacgttata
    25981 aactgaaaat gaaatatcgg ctaatccttg gtattgatcg aattcgctca tttctttccc
    26041 gctgttttgg attaaaggat cgggtaaatc agtcattttc tttttatgaa ggatgacttg
    26101 agctgctgtc tcctctgcaa acactttttt tgcgccgaag ctgtttgtga gtaatggtaa
    26161 aataaggaaa aggactccta acataacgtt tattttttta tgatttttca ttttttcact
    26221 cctgttcttt ttttgataaa caaccagatt gcaaagcttg cgaataccat accaacaacg
    26281 cctaaaagtg tatttttcgt ttcgtttgtt tttggaagaa atggacggct attttctttt
    26341 ttattgacta ctttcaatat actgtccgcc tctttatcct cagaaagaaa agttgaaatg
    26401 gtaaacggaa tttctgtttc acttaaaata taaccagaag gtgcttcgat ctcttttaat
    26461 cgataacttc ctgttttcaa cccggaaatt gaaaaagcgc catttttatc ggaaatcagg
    26521 tgaagcgcat ctgattcgtt ctttgtccac ttgtatccgt tggctgtttg ctggaggtaa
    26581 tttcctgctt tgtttttaat aaggaatact gcgccagcta atcgtttatc tggtttattt
    26641 gtctcgattt tgacaaattg cttactccct gtatatacag agactttctt tgtactgaca
    26701 ccaaaaccaa aatccagtgt tccgttgttg ttgatttcct tgttcgcctg tgctgtactg
    26761 cttagctgca tctgataaga aatggtcagt ttttttccag catatttttc caacgaaggg
    26821 atcgaaaata aaacatcaaa tccgtgaggt ttcttgtgta tgacaaagcc ttctgtcagc
    26881 ttttctccat tcgatgaaat cgttaaacta ttaggtaaaa acgttaatgc ttcatccgca
    26941 ctatctgaca attcgaactt ttgatagtca aggatattta caggaattgt cgtatgcaag
    27001 gaataagtga ttttttcacc aatcgtaaaa tcatttctag gctcttctaa taccttctca
    27061 aaaggtggat cagggtagtc gttttcttca tttttaggat acaaatggat agttgaaagt
    27121 ttttgattgt tttgtccatg tacaggaaga acaactacca tattctctgc cttttctttg
    27181 acgacttctg gtactttgga ttcaatgaaa agatacgctt tatctctttt ttcttgatct
    27241 ttagcggcca gagaaaaaga agcgatacca tcttcgttgt taagagttgt agttgttgct
    27301 tctgcggtaa acataccgga agacgcaccg ttttttgcga tctctgcttg tgcttcttct
    27361 accgttttgc ccttttcccg tagatggtaa aaagaatctg tgacatcata aacttggaat
    27421 gtgacaccat ttaatcctcg atacgtttgt aataaagctt tttcttgtcc gtcatttgga
    27481 tgatttttcg gcagttgccc gtttgggaaa agcaatttgt gtaaagtaat ctgaaccatt
    27541 tctgtttctg tttctgttgc tacctgagta aaagctggtt taaatagtaa caagaagaga
    27601 cacatactaa gccaaccaag ttttttcata tttagctgcc ccctctttct tttttcaaaa
    27661 aaagatacca aatagaaaac gcacaaccaa tcatccctac tagatagatt cctaaacggc
    27721 caattcctcc cgtttcaggt aatggtactt ttgcctgatt cgtgatgtct aaagaaatct
    27781 ggttgttttt ggctcctggt gacagaacag attcatgatc ttgtccatcc acttgaattg
    27841 acccatcttc gtgtataact atagtaactg gctcttttag accttggtat ccttctggtg
    27901 taaaagtttc ggtcagcgta taagttccag gttttaaatt ttcgaataga aaggtatctg
    27961 tttcttgtcc atcttttggc gattctaagt ccatttctgg tccctgcagt ctgaattttg
    28021 ctccttttaa tgtctgtccg ttgtcttctt ttttgtgtac cgttagatca aacgctttta
    28081 gtcgattttg atgagtgagc gtccatacat tatttgtcat ctcggtattt tttcccgtgt
    28141 aaatgatttt tccatattta tcgatttgga attcataatt tcccggcgaa gtatcatatc
    28201 cggcaggacc agctgtttca acgactcgat atttaccagg tgtgagtgaa tcaaaactgg
    28261 caagaccttt ttcattcgtt gtttggctgt caattggctg ataagtacca tttgcttctt
    28321 ttttctgtag ggaaaatgct gctcctttaa gatttatctc tttgtccgtc ccttgcatcg
    28381 catacttacg tactgctaca ggaacttcaa caaaaggatt ttcaatagtc aactggatcg
    28441 tatcatcgga agtagtgact gtttttccat caatggttac cgtaccatca gaagcgatct
    28501 tgatttccca agtagtcttt ttgcttaatc catgcccttc tggagctttt gtttctgtca
    28561 gcgtataggt catttctttt tgcaatttga cattttctgg aagagaatag gttccgtcgc
    28621 catgatctgt tagtaaagta tcaatagaat ctcctgttaa tttgaaaaca gcgccaataa
    28681 gatccttttc acctgtagag gaatttttcg ttattttcaa gtttaacggt gtgaattgtt
    28741 tagtattttt ccatgtcatt gcatctattt gttgagaatc gtatcctggt acaggtaatt
    28801 ctttgattgt ttggtaactg aatgcttgac cttgattatt gtattgaggt agtgataata
    28861 tctcttgata actttctccg ctatttgcag ataatttgtc aatgtctgca cgttcccacg
    28921 tatttgttgt atctttagct ggtttaatga ttcgaatata tccgtttttc caagctgcag
    28981 catttgtcgt atgttcccgt tgaatctcaa aagtaacttg atctggacga tcagctagat
    29041 tgttgtcaaa ttcttcccat aactttttga tgtgaagact gactccggga gctttagcag
    29101 atggtatacc gaattcagct aattcattgg tatcaatgtt tggctggaaa gttgtcctgc
    29161 cgttcatttg ataccagaaa tttggatgga agtcctcatt ttctgtttgg attctcactt
    29221 ggtaatggat ttggatttct tggtcttttc ctaaatagat ctgattgctc ttgatggtat
    29281 ttccttctat ggaaatagat ggagtgaccg ttgtaggact tgtccccaca ctcttgactg
    29341 aaagtgtacc aggctgataa atgaatggtt ctgcgattgg atcatttatt tgtccattgc
    29401 ttacagttgc tgagatctgt acagcttttt tggctaggta ttcagagata tctgttgcat
    29461 gatcagctga ttcatagtaa agatcgcctt tttcatctga tgaaaccatt tgtcgcatac
    29521 gagactctac ttctgctttt gagagaccag ctgccggatc gctttgaagt tggatgccaa
    29581 gaccatgtat ttcgattcct cgttctttga gtgccatcgc ttctccgatg gttgcgataa
    29641 acgtactgtc gattcttctg gatagattgt tttggtcagg tgcatcatag attcttgaga
    29701 ttagagaagt atttcccggc cgatcttgcg tattagaaaa ctgagttccg taataattgc
    29761 tgcttgattg tgcgtgtacc cgctgtactt tataggaaaa tgttggtaca ccatccgtca
    29821 gcaaaacgat cactttttta tgtccatttg gaacggatag catgcttcct gcatctctta
    29881 gtgctttttg tgtaaaagta ccaccatttg tccgtgaagg tgtaatggat tttacttgat
    29941 ttttcactga atcaaatgaa cccatctgta ctgcaccgtt actgtagcta tatccttcgc
    30001 ttgagtagcc gacatatccc atattgattt tgtctgtgat accgctatct gctaaagtat
    30061 cgacaaaacg atcgacacca atctttactt caccgatccg attattgtcg ttcatacttc
    30121 ctgaccagtc tacgaccaat acgagatcaa gaggcgtgat atctttttgt acatttccac
    30181 gagcattcaa ataaacatca aacaatccgg gtgtacttgt ttcctttgca tactttcgta
    30241 tcgcatagtc tgcttgatta ccggttcctc catattcgat atacgaatgg gtccgatcat
    30301 taggatctcc attccaagaa tttataccat cccattgatt tgttccgttt ttattgcctt
    30361 gatgatcaag aacatttgta tttcctgtag gttgccaact ggctttagga taagtgccct
    30421 gatcatctgt tgtatattct gtaggaatcg tttgattaga tggcacactc acagctggca
    30481 aggataatgt aggcaatgta aatgggctga cagaattttc gttttctttt gatgattctt
    30541 cttctatttc gtctggcttt ggtactgaca catctgtatc tttcttattt tctgtctcat
    30601 caataatgtc atattcttta ttatcgacga tcagcttgtt tgcctggctg tggtaaagtg
    30661 ctggatcgat tggaaaactc agatcgatag tttgtttagt gtttgatgag atttccaacg
    30721 taattttccc gctatttacc tgataagcat agccatctcc ttcttttctt tccacatcac
    30781 ttaagtaatt ttcgactaga ccaatttctt tttctatctt ttcagcactg gtgttattcg
    30841 catttagctt gatgttcagt gctttttttc cagactgatc cgaaatgact tcagctgaaa
    30901 ttgtttctaa aactgttgga tcatctgtag tgtctgctat tgcagataat ggcacaaagt
    30961 ttgataaact caatattatc agcatgaaaa taactttcag tttcttccct gtggtcgtca
    31021 tttttcccct cctttttctt tttttctgtt ttgacgtgaa tagtgaaaat tattaaaata
    31081 aacaggcgtt acataatttt atttatttta atatgataat tattatacga agggcgctaa
    31141 agggaatcac accaattttc ataccaattg gtttcattta tgaagttgat tccttcgatt
    31201 aatgagcgtt tcattgaaag aaaagggttg agggagaaaa acatatgatc aggttgttgg
    31261 aatgaaacta tagaaagatg gaaaaaatca ttcgaattct gtccatttct gacaagtgga
    31321 tgactaaaaa agaacttgcc aaacgaattg gtagttcaga atctacattt gtaaggtata
    31381 tcgaagagat caaaatccgc tggggaacgg atgtaacgat tcaatcttca caaaaattgg
    31441 ggtatcgtct tgaacatttg aatgtaccag cttatttaaa tgttctgatg gaaatgtcgc
    31501 aaagttctac aaacagtcgt ttattaaatg agattattgt caatccgggt aaaacgattg
    31561 agtattattg tgaaaaaatt tccatcagcc ggtcttcttt tacacgtaag ttgaaacaat
    31621 gcaatcaaat tttagaaagc tatttattaa aagtgatcgt tgaccaaggt tttcagttaa
    31681 ctagccttaa aagtgagctc cagttgcgta tctttgttac ctttttcttt ttaagttact
    31741 acggaagacg cacgttgcca tttccaatcg aaaaaaagaa gatcaaagaa attatggtca
    31801 agaataattg tcagatgaat ttgtttcagg aagaaagccc atatgagcaa tctttcttta
    31861 ttatgtattt tgttgtgcat ctcatgagag aatcccaagg aactccattt gaatggaaag
    31921 ctggagactc ttatgtacag ttgataaata tcgataaaaa agacttctta atcttgaaaa
    31981 atctcttagg aaaattgaag tacagcagct atataaaagt agtgaactat tttgtcaata
    32041 cgattttttc agaattttcg gagaaagaaa aaaatgaaat cagtgagcag atacgaaaaa
    32101 atatgtccta ctgttcgttt tcatccgctg attgcaaaga aaaaaacgaa gaatatgttg
    32161 ttcaattatt aacgcaaatt tattttttct cccgtatttt cccatacgat acgactcatt
    32221 tgacgatccg tgcaacttac tttgcacagc agatgcaaca ccgccagata cgtctatatg
    32281 ctggatttcg tgcagaactt caattttatt ccactctact gaatcagaat ctgatttatt
    32341 atttatctag ctatatcttt tggatgctta tcggtaatcc tgaaattcac cattatactt
    32401 ctgataaaaa aatactgatt atcagcgact taagtcttcg acatagtcaa tatattgaag
    32461 aatatatcag tgatattctt gctgtgcata aaattcactc tgagacaact gctattactg
    32521 aagatcagct gtcgaaatac aatcttctcg agtatgatct gatcgttacg aatcaaccca
    32581 ttttgaatgc ccatgttcct catatattga ttgatgatag tgtgtcattc gcaaatgaag
    32641 aagaactcat ccgcttattc gagttatgaa taatcaaaaa acagctatgt ataaaccacc
    32701 ctgataaaaa tttcaggaca aatacacata gctgtttctt tttattgtat tccttcagca
    32761 atccaacgag atttatagcg aaagtctttt aacaactctt cttttgtcca attatttgca
    32821 atgagatccg tcaaagtgtt cattacgagg gtcatggaaa agtataggaa actaactgct
    32881 tcttccgacg attgaatgga gaaatgattg attcttaata attccagcca tttttcgttc
    32941 attggagaat cagccgatag ttctctacgt ttggttgtct gctgatcatt tcgctgggtt
    33001 aacaagtata acctttgcca atagatactt tcgtgatcta agtcgcagca ccactctaaa
    33061 tatttttcga tccccaaaaa gaaatgttgt ttgttttcgc taatgaattt taagatatct
    33121 tgatggacta tgtgagaact gcttttgatc gtatacaaat aagcatcttc caaatcttga
    33181 aaatatttat aaaaagcacc gcgcgacatc cccatcttgt caacgatttc tgagactttg
    33241 acttggctga tgtgctgtga gcaaaatatc tccagtaata ggtcatcgat tctctgtttc
    33301 tttgcgttcg ataaattgaa aaaagtttct tttggcatcc acatctctcc tttatctctg
    33361 attatacgtg gatagccctt cattgtcatg aaggattcat tccttctttt tctcttcttc
    33421 tgtcaagtac ccatcttcca ttcgataaac gcgatcactc cattgaatca tacggacatc
    33481 atgagtaacc ataatagtcg ctttttgttt ctcatgagct tctttaacta gtaatttgac
    33541 gacttcatat gcatgatctg tatccaaact agctgttggt tcgtctgcta agatcaagct
    33601 tggctcatta tataaagcgc gagcaattgc cactctctgt ctttctccac cagaaaggtc
    33661 tttaggataa ctatttttaa gtgactggat atctaaagat tgcagcaagg aatcgatttt
    33721 tgttgaatct tctttttttg aagtaacttg gtcaactagt tcaaattgtt cctttaccgt
    33781 taaaaaagga atcaaattag agctttggag aataaatcct atttctttaa agcgtaaatc
    33841 tgctcgtttt ttttctggaa gctcagttag tgagtgaccg ttgatcacta tttctccgga
    33901 agtcggtgtt tgcaatcctc ctgaaatggt aaggaaagta cttttacctg aaccagaagg
    33961 accaatgatg ctgacgaatt ctccttcctt tacataaaaa tcaattgctt tcaaagctga
    34021 gacctttgta tgaccagaac caaatgtttt ggtaactttt ttcatcgtta atattttttt
    34081 catttttatt aacctcctat tgctgtaatt gggtctactt tggttatcgt acgtatcgaa
    34141 aacaatccgc ctagcattgc gacaatgatc aaaatcccac tatatagcaa ccattgtgac
    34201 caaaaaacag caaaaggcat cgcgcttggt aaaatcagac tagtcaaata agcaaacaaa
    34261 agagcaagca gaacgcctac caccccaaca ataaaggact gtgctactaa agatttagcg
    34321 atgaagaaat ttttgatccc ttgtgctttc attactccaa aaatagcagt cttctgaagt
    34381 gtcatcacgt acatgaaaat accgaccacg gcagcaacca ctaagaacaa aaagtatatc
    34441 atcgcattta aggtcatatt ttgggcagaa tagccaggaa tactttcaat gaatgtccca
    34501 atagttaata actgtagacc cttcgatgct ttttctttcg aaattttagc tgaatccttt
    34561 attacgatcc cattgatcgg ctgttcttct tcagaagcaa acggctgttg tccatacttc
    34621 aaagcagtcc acgtatctag ggacgcatag atgacgggag aaactgtgta ataagtttca
    34681 ggaaagatac cgacaatcgt caaaggatcg tcgtaactgc caattttgat cgtatctcca
    34741 attttatagc ctgaatcagc cagattttga gagatgatga tttcattctt tgttttaaat
    34801 tcatgccctt tcgtgagttt tggtaataaa aatgcttctt tcgttgtgcc gaaaactgta
    34861 acattttctt tgttttttcc tttgattgct ccgctgtaca atccgattgg tgctttctct
    34921 cctccttcaa tgtatttcag atctcctctt gttaattgtg aagctgcaaa tacttgattt
    34981 gcatcctccg acaaaacaat ctcttgtgcg tcccaatcat cgattgcttt tttaaactct
    35041 tctgaaagtc cattcgctag tcctgacaac atgaatacga catacgcaat caagaacata
    35101 ataccgacga tcaagccata tcgtaattta gaatagcgaa tttctttgat agctagaaac
    35161 atttgttttt cctccctatg atagattgat agtgacaaaa tgtcacttgt tgaatagtgt
    35221 aactctaaag tgacaatttg tcacttgtgt tgtttttttc ttatcaataa attgtctaag
    35281 acatctttcg ataaaacctt aacatgagtc ataaaaaatt tatttaagcc ttatttatgc
    35341 tttccatgat aaactaaagt gaccaaatca atgaggtggg aaaatgatta aactattagt
    35401 agtagaagac gataaagtat tatccaataa tataaaagaa atactcgctg caatcggcga
    35461 gataacacaa gtttatgatg gtagtgaagg actgttcgag ttggaaagtg gagtttatga
    35521 tcttgcaatc ttggatttga tgatgccgga aatgaatgga tatgaagtgt tagcaaaaat
    35581 acggaaagaa aaaatacaga ctccagtatt gattttgact gcaaaagata gtttggaaga
    35641 taagattgaa ggatttgaac gaggtgcaga tgattatcta acaaaacctt tctatcgaga
    35701 agaactgatc atgcgcgtga aagcattatt gaaacgctcg ctaggtctct ttgatgaaaa
    35761 tgttctgaag tataaggata tcagttgtga tttaaaaagc aatgaagtct tgtataaaga
    35821 acaagttttg cccatacaag gaaaagagtt tgaattgctc gtttattttt tacaaaataa
    35881 gggaatcatt ttgacaaaag agcagatatt tgaccggatc tggggatttg attctgatac
    35941 gacgattaca gttattgaag tttatatgag caacttacga aaacatctgc gaagtactgg
    36001 attggataaa gaaatcaaaa ccttacgtaa tgtcggttat atactgcaaa gggtgtgatg
    36061 caatgaatgg agatattaca cgaaagcaac gtagtcgctt ttttgcgaca aatgtagcag
    36121 catttgcttt tatctttttt cttttgggat tcattacttt acagatatta aaccaatctg
    36181 catacagaga aacagatctg tcattagaga aaataaattt tgattctcga acagtacaat
    36241 tagagataca aagatatcag caaggcgatc cctttttaaa cccgactcaa acggaacaaa
    36301 acagaacaaa catggaacag ccattaatgg aaccatcaaa tgaccgtttt aacactcaag
    36361 tgatcttgtg gtctaaaaat ggtgagatat tgaataaagc agctattggt gggcgtttca
    36421 accaaatcaa agaattaaaa atggatacga aaaatctgaa taccatccaa aatattgaat
    36481 taaatgaaga cagtggctca tctgccctct ctttccgttc gattacgaaa aaagcggaga
    36541 cgaatcaaga tggcgttgcc tacatccaaa ttttagaaaa tacaaatcaa atcaagaatt
    36601 cattagcgac ttttcgcacg attatgattt tgtgtatgat tgttttttgg attctctcta
    36661 ttggtatcag ttattacttg tctagtctaa gcatgcgccc tattattctt tcttggagaa
    36721 gacaaaaaga atttgttgag aatgcttctc atgaattgcg cacaccgtta acgattattc
    36781 aaaatagttt ggaacatctt tttaccaagc ctaatcatac tattattgaa gaatccgaaa
    36841 gcatcgctca agcattgtca gagacgaggc gcctcactgg attgacttcg gatttgctga
    36901 caatcgctcg gaatgattct gatcagcagc tgctttcaaa gcaaatgatc aatacacaag
    36961 aatatatcga acaacttgtt aaaccatttc aagagatggc catcatagat ggaaaagagt
    37021 ttattctcca taacgatgca acattagaag taccaattga tgaaaaaaaa atccatcaag
    37081 ttttggttat tttgctggat aatgcattaa aatatacgaa tccagaagat aagatcattt
    37141 tggattcatc tgttaaccat aaagaatggc tgattcacgt aaagaatact ggcccttcta
    37201 tcagtgaaga agatcaagca aggatttttg atcgatttta tcgggaagat caatctcggg
    37261 cgaaagagac tggcggatac gggcttggct tggcaattgc aaaacaggta atcgaacagc
    37321 atcatggaca gatttctgta tccaattatc ttccacaagg agtcgatttt aaagtccaat
    37381 tgccgttgaa gcctaaaaaa taatgcttat ccctaaaaaa gggctgtgac aaaaatcttg
    37441 tcacagccct tttttgttgc gaataaacgg tgttccagaa gtagcttctt cggaaataag
    37501 ccgaaatttc tttaagctga ccacttctgt cacaacctct ttagcttacg cttacgattt
    37561 tttattgcgg tcttcaatgt gtacatcacc gcttgtgtca atatccaatt cttctcggct
    37621 aacatcttct gtcacttttt caacatcttc atgttcttct ttatgaatcc caacttcttc
    37681 acgaataact gtatgtttgc ttacatctac ttgctcttct ttgattggga tagtaatcgt
    37741 gtcatcttcc aatttttcgt ctgttccctg tgaagattga tctgttactg gtttgcgttc
    37801 gatgacgatt tcttcacgtt tgaccggtac ttctaccgtt tcagtatcgt tgaccacatg
    37861 tttgtggatg tcgacttctc cagttgtcac atcatgtgta tttacatcta atttttcttc
    37921 ttttagttga attgtatcat catctagatt tggtttgcga tcgatgtctt cagtcttgct
    37981 tgtacccatt gtatcagtct cgccaggtac gtccatcgga tcagttcctg gtgtcatatt
    38041 caatggatcc gttgtatttt gaaagcctgt cgtgccacct acgtccattg gatctgttcc
    38101 agtgccagtt tctaatccag tccccattgt gcttgctggg ctaacagtat cttgtgtatc
    38161 cattgtatct tctgttgttt ctggctgacg atagcctttt actgtgatga caaattttcc
    38221 atcagaaata tctcctctat attgatataa aggatcattt tctggtgtag ccgtctcaga
    38281 atcataggta tcaaaagaaa aagtatcttt tattttttcc cataaagaac ggtcttcttc
    38341 accatccatc cgattttcat ctgtttcaac atctatacca gacaatccgt caaatcctag
    38401 tctagatgct gcttcatcag tagtataaat aacgatatca tctcgttcat acccttcgtt
    38461 acgcaaccgt tcaattactg ataatgcttc ttccctcgta ctatagcttc cgatgaccgt
    38521 taaatttttc tcttccatgt aaattcctcc tagcaaatag atttatgatt ggtatattgt
    38581 tacttataaa tttattctat aggagacgat tgttttctac aaatatttag attggaattt
    38641 gattaaaaca atttaattga aatttgaaaa catttatgtt aatgaaagtc atattctaat
    38701 aaaatgtcat ttgtttctat atgaattttt atgaaaaatt tcatataatt tccactcgtt
    38761 gtgatggttt aatttatcca atccatcaat aagcaaacaa cttatataaa aaaggatta
//
LOCUS       DAZKKZ010000021        38804 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.021, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000021 DAZKKZ010000000
VERSION     DAZKKZ010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 38804)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38804)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38804
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.021"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            211..1017
                     /gene="proB"
                     /locus_tag="ACG8LA_001173"
     CDS             211..1017
                     /gene="proB"
                     /locus_tag="ACG8LA_001173"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004349 - glutamate 5-kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HFQ0203482.1"
                     /translation="MRKEIKNAKRIIVKVGTSTLIYPNGNINLAAIDQLAFVLSDLRN
                     RGKEVILVSSGAVGVGMHKLHLSERPTLIPEQQAAAAVGQAELMNIYNQRFSVYNQQT
                     AQILVTRDVVDYPESRKNVRNTLEQLLIMDTIPIVNENDTVAVDELDHLTKFGDNDQL
                     SAIMAKLVAADLLIVLSDIDGFYSDNPTTNPEAQMYRYIDKIDEKILAQAGGAGSTFG
                     TGGMQSKLKAASRIFEANSAMILANGKNPAIIFDILAGKEVGTLFKEDLK"
     gene            1014..2261
                     /locus_tag="ACG8LA_001174"
     CDS             1014..2261
                     /locus_tag="ACG8LA_001174"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004350 - glutamate-5-semialdehyde
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HFQ0203483.1"
                     /translation="MTDLMQLGQQAKDSAQQLALMPTNRKNELLVQMAQTIKKNQQAI
                     IEANHKDLEKAVENNISETMQDRLQLTPERINAMATEIEKIASLDDPIGKVDEMWTNT
                     DGLRIGKKRVPLGVTGIIYESRPNVTTDAASLAFKSGNAVILRGGKEAFFSNQLLVQL
                     LQQVLVSAGESPYAIQFVDDTSHETAGQLMRLTEYLDVLIPRGGAKLIQRVKEQATVP
                     IIETGTGNNHVYIDKEAQLSMAVNIIVNAKASRPSVCNAAETLLIHSEIAPFFLPAIE
                     KELVEHGVSLRADARALEYLETAALAEDTDWDTEYLDYILAVKVVDSLDEAIAHINRH
                     NTKHSETIVTDSYAASQRFLNEVDAAAVYVNASTRFTDGSVFGFGAEIGISTQKLHAR
                     GPMGLNELTSTKYIIYGDGQIRE"
     gene            2337..2681
                     /locus_tag="ACG8LA_001175"
     CDS             2337..2681
                     /locus_tag="ACG8LA_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0203484.1"
                     /translation="MFEILMIFFIYLISLNIAAFLGVGILSLFFQFKKRSIGSQREKW
                     SQYFDKIGQKGLVTRLHISYMVALCLLATINYYSFFDHSIAYTITLLIAGIFHLSYKY
                     QLNKNHLNRTFR"
     gene            complement(2798..3124)
                     /locus_tag="ACG8LA_001176"
     CDS             complement(2798..3124)
                     /locus_tag="ACG8LA_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0203485.1"
                     /translation="MLEEYFQEVGLTLVELPIEFSDDRLIYRGYIKELPIINAEGETR
                     KAMQQKIAGMYQVYREQLLAESAEEEKEKTMNLSMDELLRYYDGETFDGFSLLNEEET
                     DLPGSW"
     gene            complement(3497..4699)
                     /locus_tag="ACG8LA_001177"
     CDS             complement(3497..4699)
                     /locus_tag="ACG8LA_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFQ0203486.1"
                     /translation="MEILENQIDIQEQTNEETKGKSSALVVAATCMIAFMGVGLVDPI
                     LKTIAAQLNATPAETTLLFTSYMLVTGVVMLFTGFLSSRIGLKKTLMTGLFIIVVFAG
                     LGGLSGNIGMLIGLRAGWGVGNALFVSTALATIVSILVGNTEKAIMMYEAALGCGMAV
                     GPLVGGVLGSGSWRYPFFGVAFLMFCGFIALAVLLPETEKPKRKVGLWEGVKALSNHK
                     LRSVGLIALLYNFGFFTLLAYAPFLLIGYSELEVGFVFFGWGVLLAIASIFVAPALER
                     KFTTYRTILAAFVLFIICLLLLGAGTSMPVLVPISIVLAGFFQGIINTLLTTIAMEIP
                     GLQRNVASSSYSFVRFFGGALAPFIAGVIGEHIGESYAFYFAGAIVLISVCCIIYHRN
                     YFATNEEE"
     gene            4816..5331
                     /locus_tag="ACG8LA_001178"
     CDS             4816..5331
                     /locus_tag="ACG8LA_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HFQ0203487.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            complement(5530..5976)
                     /locus_tag="ACG8LA_001179"
     CDS             complement(5530..5976)
                     /locus_tag="ACG8LA_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HFQ0203488.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(6023..7501)
                     /gene="msr(C)"
                     /locus_tag="ACG8LA_001180"
     CDS             complement(6023..7501)
                     /gene="msr(C)"
                     /locus_tag="ACG8LA_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HFQ0203489.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRPDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            complement(7855..8484)
                     /locus_tag="ACG8LA_001181"
     CDS             complement(7855..8484)
                     /locus_tag="ACG8LA_001181"
                     /EC_number="1.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0016657 - obsolete oxidoreductase
                     activity, acting on NAD(P)H, nitrogenous group as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HFQ0203490.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMQPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGVEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITTFE"
     gene            complement(8468..8932)
                     /locus_tag="ACG8LA_001182"
     CDS             complement(8468..8932)
                     /locus_tag="ACG8LA_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HFQ0203491.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIEH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            complement(9419..10687)
                     /locus_tag="ACG8LA_001183"
     CDS             complement(9419..10687)
                     /locus_tag="ACG8LA_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HFQ0203492.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            complement(10918..11655)
                     /locus_tag="ACG8LA_001184"
     CDS             complement(10918..11655)
                     /locus_tag="ACG8LA_001184"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HFQ0203493.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            complement(11722..12291)
                     /locus_tag="ACG8LA_001185"
     CDS             complement(11722..12291)
                     /locus_tag="ACG8LA_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DapH/DapD/GlmU-related protein"
                     /protein_id="HFQ0203494.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLLVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            12419..13291
                     /locus_tag="ACG8LA_001186"
     CDS             12419..13291
                     /locus_tag="ACG8LA_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFQ0203495.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKIFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            13633..14505
                     /locus_tag="ACG8LA_001187"
     CDS             13633..14505
                     /locus_tag="ACG8LA_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HFQ0203496.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            14502..16460
                     /gene="nagE"
                     /locus_tag="ACG8LA_001188"
     CDS             14502..16460
                     /gene="nagE"
                     /locus_tag="ACG8LA_001188"
                     /EC_number="2.7.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015572 - N-acetylglucosamine
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-specific PTS transporter
                     subunit IIBC"
                     /protein_id="HFQ0203497.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAAARPAQTNTVVKTETFAGETIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVEEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(16711..17562)
                     /locus_tag="ACG8LA_001189"
     CDS             complement(16711..17562)
                     /locus_tag="ACG8LA_001189"
                     /EC_number="1.6.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016655 - oxidoreductase activity, acting
                     on NAD(P)H, quinone or similar compound as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HFQ0203498.1"
                     /translation="MHYLVTGATGGFGGYALEFLKKMVPQNEIYVLVRSEEKGEALKE
                     AGFNIRIGDYDDLDSMKEALKGIDRLLFVSGVPGNRQAEHKNVVKAAQAAGVSYIAYT
                     SFADADHSISVLAPDHQFTEKMIKDSGISHTFLRNNWYVENELPIIGQALKTGQFVYA
                     AGNGKTGWALKREYAEAAAKVLVESDSPEILELSGNLTDYEELAKALERATGKELEII
                     EASDAAFVENLKEAGFPQEAADMFLAIQHDIKKDQLAISSDDLEKVLGKPLTSLEAAL
                     KEILDQE"
     gene            17685..18152
                     /locus_tag="ACG8LA_001190"
     CDS             17685..18152
                     /locus_tag="ACG8LA_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HFQ0203499.1"
                     /translation="MKYSLQFSDAIHVLAYIEMFQDTRSLSSEMIASSIETNAANVRK
                     IMSQLKKSGLIFTKTGKPQPSLAKSPDQISLLDVYRSIEGNTQLIQVDPKTNPNCVVG
                     ANIQEALEESYARLQKKAEEEMAKITLDSLIHKIAVLEKEKRPENTGLVERFL"
     gene            complement(18415..18897)
                     /locus_tag="ACG8LA_001191"
     CDS             complement(18415..18897)
                     /locus_tag="ACG8LA_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HFQ0203500.1"
                     /translation="MAKYRIEEKPDFTVTGIGVELKSSNTDFVGLAAEKQAFEQKVIG
                     NGTIDALKQAAENHYFFTVNEPYNGKMMYYVGVQTSQDVPNTTRIIPFPKGTYLVVSA
                     LAESPEELRNDLTNTAFGHVLREVEDYAYVGGPNAVVEMGVTNGKYMGEIWIPVVNKP
                     "
     gene            complement(18997..19860)
                     /locus_tag="ACG8LA_001192"
     CDS             complement(18997..19860)
                     /locus_tag="ACG8LA_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HFQ0203501.1"
                     /translation="MLKDLNQLIDYIEEHLTEGLSYKIIAENTGISEYQLKRIFTFIA
                     GMSLMDYIKNRRLALANRDLLDGSRVTETAFRYGYETVEGFSRAFRDWSGYLPSEISR
                     YGIQKSFPRLTFFIDVRGGKSMEFRIEKKEQFYVAGVAKKVPVKFEGVNQEIQKLAQT
                     ITETQREEMHKLGDLYPNQVINVSYGFDGDRLEEKGSLMHMIGFATTKENPYADLEML
                     AIEEHTWAIFPNKGPFPQTLQDTWGKIYAEWLPSSDYGLVEAPEISFTKWGEDFSNVY
                     SEIWIAVKAKK"
     gene            complement(20357..21544)
                     /locus_tag="ACG8LA_001193"
     CDS             complement(20357..21544)
                     /locus_tag="ACG8LA_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS16 family transposase"
                     /protein_id="HFQ0203502.1"
                     /translation="MTQVHFTFESEEIQAIINESGANDTAKTLMTIMFNQLMEEQRNQ
                     YIQANAYERSEERQSQRNGYYDRSFTTRIGTLELHVPRTRDGKFSPTIFERYQRSEKA
                     LIAAMIEMVISGVSTRKVTKTVELLTDGATVSKSFVSNLMKQLDPFVFEWRNRSLEGS
                     EYPFFMCDALYMKVRENHRIVSKGVYIGIGIDSDGRRTILGFDVQDGESEDNWDTVFQ
                     SFVQRGLFGVKLVISDAHKGLVKAVRKNFLGASWQRCQAHFLRNIFDKLPKKVSSDVK
                     DELKSIFKASELELTRERKEHFLEKYGCDSKLSAACDILENGFEDAIQILSFPENIRR
                     RIRTTNVLERLNEEIRRRERVIRIFPNINSITRIIGTLLMEKDTEWLASPRKYLEFNS
                     NNI"
     gene            21932..22780
                     /locus_tag="ACG8LA_001194"
     CDS             21932..22780
                     /locus_tag="ACG8LA_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SWIM zinc finger family protein"
                     /protein_id="HFQ0203503.1"
                     /translation="MNNWLEYFPENVLERGYSYHLHGFVRHLNYTSKYLSATVSGTED
                     YKVVITWDEKTNMTCDCLYAIEGKKCKHMAAVLFAYEERPIKKSNYSLSELSSLVSSA
                     SSSLVRELLTEILIEHPHFIERFKVKMPFHAINYSDKLTTIIHKYDHIIKKNKNRKTA
                     KFIMEMRKFIQEAVESLIQQNAYLPAFELINEVIATLETFYWEPEDERTLLLIEDCYY
                     LWKELLAEAPHAEKRQMFSWFVCQVDHTDASYSKRYSIKILKEDFREKEFSNQKKKID
                     KKLKKR"
     gene            complement(22951..23292)
                     /locus_tag="ACG8LA_001195"
     CDS             complement(22951..23292)
                     /locus_tag="ACG8LA_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FGGY-family carbohydrate kinase"
                     /protein_id="HFQ0203504.1"
                     /translation="MVGLKRKELAGRRFTRIVSVGGGAKNLAWLQIQADIFDATVYCL
                     SVEEGPALGATMIAALGLGWFDTPESCCQNFIQYTDAVEPLLQNVEKYHKIYQQCRKI
                     YPATKEICHDL"
     gene            23378..24085
                     /locus_tag="ACG8LA_001196"
     CDS             23378..24085
                     /locus_tag="ACG8LA_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HFQ0203505.1"
                     /translation="MDEKLDIKTAIKDTLPTVFGYIGIGLAFGIVGKAAGFHPLVVTL
                     MSLLVYAGSAQFITVSMLASHSPLLSIVFSTFLVNSRMILMSMTIAPYFKKNRLLQNL
                     LIGTLLTDESFALGMNKLNYTGQKLNFRWMNTANWISYLTWVGSSLVGALLGNFITDP
                     KKFGLDFAIVAMFIGLLYLQVISDRNTSKRLQLILIGLTLILVYVGLIFIPSNLVIVV
                     VTLIGCGLGVWIKHAFF"
     gene            24072..24395
                     /locus_tag="ACG8LA_001197"
     CDS             24072..24395
                     /locus_tag="ACG8LA_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HFQ0203506.1"
                     /translation="MPSFEFTLLTILGCTLATWLSRVLPFVLLKKFDLPQPLLEYLSF
                     VPIVIMSALWFSSLFTQNIGHLPQINLENALASVPTLLAAILSKSLLVIVLAGILSLS
                     LIRLL"
     gene            complement(24484..25521)
                     /locus_tag="ACG8LA_001198"
     CDS             complement(24484..25521)
                     /locus_tag="ACG8LA_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase family
                     protein"
                     /protein_id="HFQ0203507.1"
                     /translation="MSEKELMKVVGFYEGLPIDDPKSFIDEKEQIPVPSSRDLLVKVN
                     AVSVNPVDTKLRQDNGIRNALRILGFDGVGKVVAVGDEVQKFSVGDRVFYAGTTTRAG
                     SNQEYQLVDERIVALAPKNLSDEEAAALPLTSLTAYELLFEKFGLTPEENANRGKKIL
                     VINGSGGVGSILNQLAHWAGLEVYATASPKNFEWLKKTGVDYPIDYHHDLSKSFRELG
                     IDQVEYVAVLFDITRYFDQIKHLVRPFGHVGTIVGIKEPLDIGVWKNQSISFDWEYMF
                     AKTDYNYEIETQGEALAHIAALANEGIIRSTLSKVYSDGMNAKNLKQATKDVETGHML
                     GKVVVSGPFNG"
     gene            complement(25968..26951)
                     /locus_tag="ACG8LA_001199"
     CDS             complement(25968..26951)
                     /locus_tag="ACG8LA_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase"
                     /protein_id="HFQ0203508.1"
                     /translation="MTTNFWKELPKPFFVLAPMEDVTDVVFRHVVKHAAAPDVFFTEF
                     TNSDSFCHPDGKDSVRGRLTFTEDEQPMVAHIWGDKPEFFREMSIAMAEMGFQGIDIN
                     MGCPVPNVAERGKGSGLILRPEVAAQLIEAAKAGGLPVSVKTRIGYTEMSEMEEWISH
                     LLHQDIANLSVHLRTRKEMSKVDAHWEVIPKIIALRDQIAPQTLITINGDIPDRQTGE
                     ELAEKYGVDGIMIGRGIFKNPYAFEKDPREHTEKELIGLLRLQLDLQDHYSEIIPRSI
                     TGLHRFFKIYIKGFPGANDLRVQLMNTKSTDEVREILETFEKEHPTLFSEQ"
     gene            complement(27367..28137)
                     /locus_tag="ACG8LA_001200"
     CDS             complement(27367..28137)
                     /locus_tag="ACG8LA_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFQ0203509.1"
                     /translation="MFNLYFTALKSLAIKETNRYLRIWVQTLVPPVITTSLYFVIFGK
                     MIGGRIGDMGGFSYMEFIVPGLIMMSAITSSYANVSSSFFSQKFQKNIEEILVAPVPT
                     HVIIWGFVIGGVGRSILVGSLVTIISLFFVPLHVYSWFMVIITLLMTAILFSLAGLLN
                     GIFAQSYDDVSIVPTFVLQPLTYLGGVFYAISMLPPFWQAVSKVNPIVYMISGFRYGF
                     LGTIDVPVATSMIVLVLFIVVLYAVTWYLINKGRGLRS"
     gene            complement(28130..29065)
                     /locus_tag="ACG8LA_001201"
     CDS             complement(28130..29065)
                     /locus_tag="ACG8LA_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0203510.1"
                     /translation="MANALEINNLKKIYGSGVEALRGIDLSVKEGDFYALLGPNGAGK
                     STTIGIITSLVNKTSGKVNVFGYDLDKDLVRAKQQIGLVPQEFNFNPFETVQQIVVNQ
                     AGYYGVSRKEAMKRSEKYLKQSNLWEKRNVRARMLSGGMKRRLMIARALMHEPRLLIL
                     DEPTAGVDIELRREMWEFLRELNENGTTIILTTHYLEEAEMLCRNIGIIQSGELIENT
                     SMKELLSKLQFETFIFDLAPYDTKPVIEGYACTFEDEQTIAVEVERNQGVNGIFDQLT
                     RQGIKVLSMRNKSNRLEELFLKITEENNHTEEKNV"
     gene            complement(29659..31308)
                     /locus_tag="ACG8LA_001202"
     CDS             complement(29659..31308)
                     /locus_tag="ACG8LA_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HFQ0203511.1"
                     /translation="MGQREFIVLIIIAVVILLVVLDIFSRLKVKETVRSNWGKIPYQP
                     RFDKEESLKDAWLTEKKFRSWDSEIDDLTWYDLDMFEVFEGINSTYSSVGSEALYQRL
                     RSFDFGEDYQLEKLIAFYQENPQLRERIQYQFARLGKKDHNFAKQYLADGKSKKIGRV
                     GLFIFLGLLPLVGVGLLLLGQVLGIYLAIGGLVFNTVYYLVKKQTLETELNSMSYLVS
                     TISAANQLAKMTTPLQKELKQQTKPLRDIPKLGFSFRMKSGSEAELIFEYVNIMFMLP
                     FISYHFVLTKLEKHSTEAIKLWELLGELEVAAAVLNYRTYMPITCRPEFTEGGVTAKD
                     IYHPLLKEAVVNPVNWQKNTLVTGSNASGKSTYVKSIAISCILAQTIQTAIAEQFTLQ
                     PGHVLTSMAIEDDLFEGDSYFVSEIKSIKRLLDQVASKERCYCFVDEILKGTNTIERI
                     ASSASVVRWLAEYPSLAFVATHDIELTEILKNYCENVHFEEQVTEGKGISFDFKLKEG
                     PSRTRNAIALLKVLNYPKSIVEQAQKESLLFDEQRQWYPFD"
     gene            complement(31503..32399)
                     /locus_tag="ACG8LA_001203"
     CDS             complement(31503..32399)
                     /locus_tag="ACG8LA_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFQ0203512.1"
                     /translation="MIKWLLLLVVIFMGSFIFFLQREIKRLTKKIATLSERQEYGGRL
                     SVEFREKNLMDLVDALNTWVDENEQKGQAFQEMEENIRLSIVGLSHDLRTPLTAINGY
                     VQLLEQVEDTEKREKYLTIIKQSVARLLSMTDQFYDLARIETKQKEMDLHTLSFSKEV
                     EEVFFSFYEQFSEKNIEVAFAEHSINTTVLADPLMLLRVLQNIIQNLLRYADGQAKVT
                     FSKEDSFIRLTVANPIKPGAQTSVEKVFQRFYTENTSRTNTESSGIGLYLSKKLVEGM
                     GGEMTARLDGGIFSISVKLRRV"
     gene            complement(32392..33072)
                     /locus_tag="ACG8LA_001204"
     CDS             complement(32392..33072)
                     /locus_tag="ACG8LA_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFQ0203513.1"
                     /translation="MFLLETILIIEDDEAVHSLLEEVLEQRYKLLDAYSGTEGKLLLS
                     TYPVDLILLDLMLPGLSGEALLAEIRQTSNVPIIVLSAKSDQRDKVSLLAAGADDYVT
                     KPFDIEELLLRIGIQLRHQTSVQVKDLSQRIYYKEILLDKESRDVNVNGVAVHLTGRE
                     FDLLKLFLEHPKKVFSRANLYETVWQEPYFDSEKTVNMHISNLRGKLAKAHAVYIHTV
                     WGVGFRFD"
     gene            complement(33073..33855)
                     /locus_tag="ACG8LA_001205"
     CDS             complement(33073..33855)
                     /locus_tag="ACG8LA_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HFQ0203514.1"
                     /translation="MFNLLTAEKIKVWKSRKMWVSLGLMVVLPLFYSWNEWYMHTKYG
                     NELNQATDTVINGATGILMVEKMAAWILLAFAAFACFYIGEEFQNGTIRNTLSLGRNR
                     MTYYVSKLLVTLLITTLGVVLITGLAMIAYTLAFGFGEVEGIKNYGNYVLKVFPVLLL
                     LILATLSVPVALTFITRSTSVSLLLSFLYIMGTAFVPGVFAKIKGLEFLTEWFTETWL
                     MYTDFAQQATYSQAPKMILVSLVTIVVSSALGMFIFQKSDIK"
     gene            complement(33848..34765)
                     /locus_tag="ACG8LA_001206"
     CDS             complement(33848..34765)
                     /locus_tag="ACG8LA_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HFQ0203515.1"
                     /translation="MDFGNETVLKATGITKKYGAAKALDKVSIEIKRGMIYGLIGENG
                     AGKSTFMRTIMGLISIDEGSIELFGTTDLQAARRRMGQSIETPALYPELTARDNLRIQ
                     AANGGVSDREIEDLLKMMRLENTGKKKAKNFSLGMRQRLAIANALITNPEFLILDEPT
                     NGMDPAGMAEMREIIQRLVKERGITVLLSSHLLDELSQIATHYGILHEGHLIKELSKE
                     ELAQESRQFIKIDTSATEQAVTVLDSLGYRDYFVQSSRVIQLFEGIDQVAAINQALVE
                     AKVPVDGIHLVGQKLEDYFLQLTGGNPHV"
     gene            complement(34768..35052)
                     /locus_tag="ACG8LA_001207"
     CDS             complement(34768..35052)
                     /locus_tag="ACG8LA_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0203516.1"
                     /translation="MFSFAFYMVWLQREVPTHIQGRLMSTITTITMVASPLGLALFGA
                     LFDWQTTQPRLRDSLIFLEIQLENLHFLYTFLAAFFIPVNYTSLINKKEG"
     gene            complement(35753..36373)
                     /locus_tag="ACG8LA_001208"
     CDS             complement(35753..36373)
                     /locus_tag="ACG8LA_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0203517.1"
                     /translation="MNINRVIKLIGAKNINKVRSEFIFPEDFFNWFFYQFSECKRLLG
                     ENYYLKGIGGFMGNVADEQNIIKGISEQTSELTVTKAFISNGESLKNVTARIRKENEV
                     DIVFGIDHECNSVIYVTQSANLILFENGCKDDFMVVYLYDILIPKLRSLYMSSESIFV
                     SEQKGSFSKKIGIEVIESIMCHNHITLEELEILIGQKNNNTKIQVS"
     gene            complement(36454..36864)
                     /locus_tag="ACG8LA_001209"
     CDS             complement(36454..36864)
                     /locus_tag="ACG8LA_001209"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0203518.1"
                     /translation="MVTLFYRRDFLFSIYTKYFTLSSNIKTSTKLICKLFKLDKISNI
                     DDVKSKILTRKVSEPVKLTAQDKKNGIVLYGDDAKYNYNWDTSSEAEVLSIPTTDTSG
                     EKVTFKINFITAISKLEYGKQKKRDNNDQYLPKK"
     gene            36894..38072
                     /locus_tag="ACG8LA_001210"
                     /pseudo
     CDS             36894..38072
                     /locus_tag="ACG8LA_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324322.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISEfm2 family transposase"
     gene            38249..38535
                     /locus_tag="ACG8LA_001211"
                     /pseudo
     CDS             38249..38535
                     /locus_tag="ACG8LA_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368756.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT        11696 a         8050 c         6835 g        12223 t
ORIGIN      
        1 aactactcct attctaacat atccgaggct gtaaaagact ttctttacaa attcttcaag
       61 aaattctgct atcttaaagt aaaccattaa ttcgttcttt ttccaaacga ctacaagttg
      121 tacaaaaaaa ctatttttta catgacttta ctcgtcaaaa caagtagaat agaacgaaat
      181 taatgagtgg atatttgatt gaggtgtcac atgcgtaaag aaattaaaaa tgcaaaacga
      241 attattgtca aagtaggaac aagtacattg atttatccca atggaaatat caatcttgcg
      301 gcaatcgatc agttagcttt tgtcctttct gatcttagaa atcggggaaa ggaagtgatc
      361 ttagtctcat caggagctgt aggcgttggt atgcataaat tacatttgtc agaacgtccg
      421 actttgattc ctgaacagca agctgcggcg gctgttggtc aagccgaact gatgaatatc
      481 tataatcaaa gattcagtgt atataatcaa cagacggcac agatcctcgt gacaagagac
      541 gtggtagatt atcctgaaag tcgtaaaaat gtgaggaata cattggaaca gcttttgatt
      601 atggacacga tccctatcgt gaacgaaaac gatactgtag cagtggatga attagatcat
      661 ctgacaaaat ttggcgataa tgatcagctg tcagccatca tggcaaaact tgtcgcggca
      721 gaccttttga tcgtcctttc tgatatcgac gggttttatt cagataatcc gactacaaat
      781 cccgaggctc agatgtatcg ctatatcgat aaaatcgatg aaaagattct ggcacaagca
      841 ggtggtgctg gtagcacatt tggaacaggc ggtatgcaga gtaaattaaa agccgcttct
      901 aggatatttg aagcaaacag cgcaatgatt ttagcaaatg gaaaaaatcc ggcaattatt
      961 tttgatattc ttgcaggaaa agaagtaggt actttattta aggaggactt gaaatgactg
     1021 acttgatgca attaggacaa caggcaaaag atagcgcgca acaactagca cttatgccta
     1081 caaaccgcaa aaatgagcta cttgttcaaa tggcacaaac catcaaaaag aatcaacaag
     1141 cgatcattga agcaaatcat aaagacttag aaaaagcagt cgaaaacaat atcagtgaaa
     1201 cgatgcaaga ccgcttgcag ctgacacctg agcgaatcaa tgccatggct acagagatcg
     1261 aaaaaattgc ttcgttagac gatcctattg gaaaagtaga tgagatgtgg acgaacaccg
     1321 acggattgag aatcggcaaa aagcgcgtgc cactaggcgt gaccggcatc atttacgaat
     1381 ctcgtccaaa tgtcacgaca gatgcagcta gtctagcatt caaatcaggg aatgccgtta
     1441 tccttcgcgg tggcaaagaa gcattcttct cgaatcaatt attagtccaa ttattgcagc
     1501 aagtactggt cagtgctggc gaatctcctt atgccatcca gtttgtcgat gatacttctc
     1561 atgaaactgc aggacagttg atgcgattga cagaatactt agatgtgctg attcctcgag
     1621 gcggagcaaa attaatccaa cgagtcaaag aacaggcaac ggtacctatc attgaaacag
     1681 gtacaggaaa taatcacgta tatatcgata aagaagcaca gttatctatg gcagtgaaca
     1741 tcatcgtcaa tgcaaaagct tcccgtccat ctgtctgtaa cgcggcagaa acattgctga
     1801 tccattctga gatcgcacct tttttcttgc cagctattga aaaagaactg gtagaacacg
     1861 gggtctcttt acgtgcggat gctcgtgcgt tagaatatct agagacggct gctttagcag
     1921 aagacacaga ttgggatact gaatatctag attatatcct tgctgtcaaa gtggtcgatt
     1981 ctttggatga agcaattgca catatcaatc ggcataatac taaacattca gaaacgatcg
     2041 tgacagatag ttatgcggct agtcaacgtt tcttaaatga agtggacgcg gcggctgtct
     2101 atgtcaatgc ctccactcgt tttacagacg gatcggtatt tggttttggt gcagagattg
     2161 gtatctctac tcaaaagttg catgcccgtg gtccaatggg gttaaatgaa ttaacttcca
     2221 caaaatatat catttatggc gatggacaaa tccgcgaata atgtttcgtg tgaaacatta
     2281 ttcccgcctt ttgccttttt tctgtaaagg ttctatccaa ctagaaaggt gtcaatatgt
     2341 ttgaaatttt aatgattttt tttatttacc ttatttctct gaatatcgct gcttttctgg
     2401 gagtcggtat tttatccctt ttctttcaat tcaaaaaacg aagcataggg agtcaacggg
     2461 aaaaatggtc gcagtatttt gacaaaatcg ggcaaaaagg gctggttaca cgcttgcaca
     2521 ttagttacat ggttgcatta tgcttattag cgacaatcaa ttactattct tttttcgatc
     2581 attcaatcgc ttatacgatt acgctactga ttgctgggat ttttcactta tcttataaat
     2641 atcagctgaa taaaaaccac ttgaatcgga ctttccgcta aaaaatatcc gtacgataag
     2701 tagagtgcct tgaagatcgg caaaaaactg ccggactttt tagaggctgt gacaaagatt
     2761 ttgtcacagc ctctttttcc atataaacgg cgttcgccta ccagctgcct ggtaaatctg
     2821 tttcctcttc gttaagaagc gaaaatccgt caaatgtttc gccatcataa taacgaagca
     2881 gctcatccat ggacaagttc atcgtttttt ctttttcttc ttccgctgat tcagccagta
     2941 gctgttcccg atacacctga tacataccag ctattttttg ctgcatcgct tttctagttt
     3001 caccttccgc attgattatt ggcaattctt tgatatagcc acgataaatc aaccgatcat
     3061 ctgaaaattc aatgggtaat tcaacgagtg tcaacccgac ttcctgaaaa tattcttcca
     3121 gcatctatta tccccccatt ctttttctta aatgaatttt agcttaccta ctgaaaattt
     3181 tccagtttca ttattttgag aaaaaaaggg aatgtgacaa aaatcgtgtc acatcccctt
     3241 tttccgaata aatggtgttc ttctgccaac tcctcaatca taagtcacaa tattcaacaa
     3301 acatgagaaa ctgttttttg aaattgttcc ttgtgattca gagttaaacg acagtctcac
     3361 aacctcttgg taaacggcgt tcaaaagctt gcatctgcgg taataagccc aaccaaacga
     3421 aaaatatgag aagctatttt tgtttggctg ttcttatgac ttgatgcagg acagcttttt
     3481 cacaacctct gatttcttat tcttcttcat ttgtagcaaa ataattacgg tgataaatga
     3541 tacaacatac actgataaga acaatggcac ctgcaaaata aaacgcatag ctttcaccaa
     3601 tatgttcacc aatcacacct gcaataaatg gtgctaaagc tccaccgaaa aagcggacaa
     3661 aactatagct ggacgaagca acgtttcgtt gcagacctgg tatttccata gcaatcgtcg
     3721 tcaacagtgt attgataatt ccttggaaaa atcctgctaa cacaatgctg atcggtacaa
     3781 ggactggcat agaagttcca gctcctaata acagcaaaca aataatgaat aagacaaatg
     3841 ctgctaaaat tgtccgataa gtcgtaaact tccgctcaag agccggtgca acgaaaatcg
     3901 aagcaatagc cagaagcaca ccccagccaa aaaatacaaa accgacttct aattcagaat
     3961 agccaatcaa taaaaatggc gcatacgcaa gtaaagtaaa gaatccgaaa ttatataaca
     4021 atgcgattag tccaactgaa cgaagtttat gattgcttaa cgctttgaca ccttcccaaa
     4081 ggcctacttt tctctttggt ttctcagttt caggtaaaag taccgctagg gctataaaac
     4141 cgcaaaacat caaaaatgct accccaaaaa atggataacg ccatgaacca ctgcccaaga
     4201 ccccaccgac tagagggcca acagccattc cgcagccaag tgctgcttca tacatcatga
     4261 ttgctttttc tgtgttacca actaaaatac tgacgatcgt tgctaaagca gtagagacaa
     4321 ataaagcatt cccgacaccc cagccggcac gtaacccaat cagcattccg atattcccag
     4381 ataatccgcc aagaccagcg aatacaacga tgataaacaa tcctgtcatc aatgtttttt
     4441 tcaaaccgat ccgactagat aagaaacctg taaatagcat caccacacca gtgactaaca
     4501 tgtaactagt aaataacagg gtcgtttcag ctggcgtagc gtttaactgt gcagcaatcg
     4561 tttttaagat tgggtctact agacccactc ccataaaagc gatcatacag gtagctgcta
     4621 caactagcgc tgaacttttc ccctttgttt cttcatttgt ttgttcttgt atatctattt
     4681 gattctccaa tatttccatc cctttctctc tattagcatc atacatgatt tattttacat
     4741 gtaaatatgc acatgtaaaa cgtggaaact ttactgtgat ataataaaga aaataagacg
     4801 agaggtagga tttttatgaa tactttagcc tatatattat tatgcgtgct tttatccaaa
     4861 ccacgttctg ggtatgaatt gaagcagctg atcacaattt tttgggaagc ccatcacagt
     4921 cagatctata caacgcttgc caagttagac cagcagggtt atgtgaccgt tttggacaaa
     4981 gacgagcact ctcaaaaaaa gatctaccac ttgactgatg aaggacgtgc tcttgtagag
     5041 gaatggatca aagaggaaac tcccgctcct acgcaaaaag atgaatttct agcaaaaatc
     5101 tatgcttttt cgacgctcga taaaacaaca gctactggac tgctattcac tagagaacaa
     5161 cagctgaaca aaatcatgca aaaaaatcaa aaaaaattga atgacctctc gctagacaag
     5221 aaacaagaat ttggacgtta tgttgtgatc cagcgcagaa ttatgctttg tcagcaggaa
     5281 ctccaatggt gtcagcaagt aagagaacaa atgcagcagt tttttgagta agggataaac
     5341 agaacctttc tagaaatatc tattgaagag caaattatct tcaataaaag agcaatacag
     5401 ttggaaaaga aaaagcgatc cgaacgacag gccaaaacct atcgttcgga tcactatttt
     5461 tctagaactg cattcaagag actatgacaa aaagcatgcc aaggcctttt ttcaaataac
     5521 agtgttccat cattcattac tttgaattgc ttttagcaca cttcttgaaa gcgggccaac
     5581 gatgatcaac tgcaacggta aagcggcaat cacattcatt ttccaagcat tcatataagc
     5641 agagaataat tgatcaggta ttccttgttc catgatcaca ccgaataaag acatacatgt
     5701 caccattcct aaaaccatca agcatgaaat agttaagatc atttggacct tgctttctgg
     5761 atttactggt agtttaaagg caattttttt cgccagcaca ccgatgatga agacatccaa
     5821 aatgaaagcc accacgaatc caggcactag accaatcaac aaacttgata aatgaagatc
     5881 ttgatgcagc cataaattat acgcgctcat ccccaagacc atcaaaaaac acatcattgt
     5941 tgtaaaaatt attccttctt ttttatttgt aggcaatctg taccactcct ttaaatttgt
     6001 cacgaaaatc atcgtagcac atttaaaaat ttctcgtaag tacttttttt attttctgcc
     6061 cttttatttc ataaacttca tcagccgtac gctcgacaaa gtaagaatca tgagaagtaa
     6121 acaaaatcgt tcccggatat atttgcatta gcttctctaa agcttcgatc gttgccatat
     6181 caataaaatt agtcggttca tctaacagca acacattact tggcttagta aaaagcaaag
     6241 caatcgtcag acgggtcgct tctcccccac ttaatgtaca taacggtttc gtcaaagttt
     6301 cctgagcaaa ccctaagtga ttcagcaaac tacggacaag cgattctgaa aactctgttt
     6361 gtctcatgac aaaacgaatg atggattctt cagatgtcat ttgataaccc ttttgctgat
     6421 atacttgaaa gcttactttc ggagagagaa ggattccttc tccttgtttg cggatatgtt
     6481 ctaataaggt tgtcttacct gaaccatttt caccgacaat cgcgattttt ttacctaaag
     6541 aaaactgaaa atcaccattt accagtaatg ttctcccact tctttccaat tggacatttt
     6601 gtcccatgat gggatagcgg ctgtggagtt caagagattt tggtactgga aaacggattt
     6661 gtttcatctg ctgcggcttg gttgtttctc ctattttttg gagtcttctc tctaatgttt
     6721 tcgcattctt ttggatggct ttttgtacac tgtctttttg tttagaggaa gacaaccgat
     6781 ccggtctgat ttgttgcttt ttctttttac tggacacttt ttccaacttt tccgcttgtt
     6841 ttttcttttc ttggatcgat ttttccaatc gttttttctc tttcatgatc gactctgctt
     6901 ctcgtagctg agtctttttc tccaattcct tttgagtgag ataggcacta taattccccg
     6961 aaaactctcg gatttctccg tcttttactt cccagatttt cgatgctagc tcatctagaa
     7021 aatagcgatc atgactaaca aaaaccagcg taccataata ataacgaagc tcttcaatca
     7081 gtcgatcaat actttttcta tctagatggg ttgttggctc gtctagaagc atcccttgtt
     7141 cataagaaga aagaagacgt atcaactcga tctttcgttc ttcccctccg ctccatttcc
     7201 gctctgaagt ttcttccagt cttaactgga aatgactggc taattccaaa tttaggtcct
     7261 ttgcttcagc gagataggtt aattgaggca ggtagttgaa ggtgatctct gtttggattt
     7321 tcccatgatc gggaaaaagt tcaccggcta ttagtttgag caaagtcgat ttaccgacac
     7381 cattttctcc tatgatccct atacgatctt gctgatagac acgaagagaa tcaatagata
     7441 gttctagctg gttgccaaag ctgacttgta gatttgttat atttactgct aaattttcca
     7501 tatgttttac actcctattt catgtaaaac aacaattatc gatactaaaa aagagcagaa
     7561 aaatctgttt gcaaaaaaac tgcatcacat cttttcctac tctgaacgaa ataactatga
     7621 ctaaatcacc aaatctgtca tagctttcac ctattctact gtcgttcgaa aaaatggaca
     7681 tactccatcc atgaaattgt tgtttataca tgtcttttga atttatttag ttgttattca
     7741 aaagttcgaa acgtaatttc atcgatgcag tcatttttcc gacctccttt tttattaggt
     7801 taccacacac gattcaaaaa aagcaatagc tactgaatag taactgaaaa ccttttattc
     7861 gaacgtagtg atcttttctg gtgctaaacg aacagactcg taaccttctt ctaccgcttt
     7921 tcctattgat aaaataataa ctggaacata acggtcttta tccaaaccaa atgcctctgc
     7981 caactgatct gcttcgactc caccaattgg atttgtttca tagccatgat cacgcgcaac
     8041 taacatgaat tgcatagccg ctaagctaga atcgactttg actacatcgt tcatttcttc
     8101 tcttgaaaaa ctcttgtaat aaggaatgat cgcagctaat tgttgatctc tgacttcttt
     8161 tggcatcttc cctgattcgt aagcttggtt atagatttct tcgccatatt cgtaacattg
     8221 catatcgcca aaaatcatga ccattgcaga agaagtatca ttttgtctcg tattgaaacg
     8281 gatcaaagga cgcaagattt cttttgcttc ctcgctttca gcgaccacaa agcgccatgg
     8341 ttgcatattg acagaagaag gtgcagtcgt cgcttctttg atcatttcca gcatttcttc
     8401 gtgtgggatt ttgtatgttt catcatatac gcgaacggat cttctaccag tcataattgt
     8461 tgaaaaatca tttttttgtt ccattattat taacctcttt cgtttctgtt gttatattgc
     8521 aaagttgggt attcaattta tctaaaagtg ttagaaattg tttcatttct acatcgctga
     8581 aagccgggga tagcacggaa cctgtatctt tatggtccat ttcacaatgc tcgattttct
     8641 tctgggcttt ttctgttagc gctacataca cttcccggtt gttctgagga tttctctgac
     8701 gcgaaacata gccatttgct tccaatacct tcagatgacg agtaactgct ccttgatcaa
     8761 tctgcaactt ttcttgcaaa ctgctttgta gcaatggatt ttcttctttc agtctcatca
     8821 tgatctcgta tctagtaaga cttataccga tattttcttc aaagatctgg acgatttttt
     8881 gatcggctaa tttgatttga tataaaaggt gactaatctc ttctaaagac ataatttcct
     8941 cctttctaat aattgactcg tcaacgattg acttgtcaat aatagaataa aaaaagaaaa
     9001 aagtcaaaga atcagctgtg taataaaaaa aacgctctca atagaaaagt atagagaaaa
     9061 gaaatttttt gtagaatgaa cggaaaaaat gataaagaaa gcacaacgct aaaaccaaga
     9121 ttattgattc ttatcaaact atagaagata gctcttctgc agtagaaaat tttacaccgc
     9181 caaaaatttc cgaaatcgcc ttttgcaaga atcccgtcga atattagaaa ttggatcagt
     9241 atgcttaaac agtaataaaa aagttatgac aagatgttgt cacaaccttt tttgagtaaa
     9301 cggtgttcaa aaacttgcat ctgcggtaat aagttcaacc aaacaaaaaa catgaaaatc
     9361 tgtttttgtt tggctgttct tactacttga tgcagggcag ctttttcact acctcttttt
     9421 aataaccata aaatcctatt ccttcatatc tccagcccat cggtgttagc caatctcttt
     9481 ccttagcact caaggtatag tgatgggtac cagttttttc atttggatta aatagtcgat
     9541 aaattggctt ggaaccacca gaataaaaac ttagaccttc ataacgccaa ccgatttttg
     9601 ttaaagagtt gatctcagat tgtgccattg tgtaatgatg gtctccactg taaggattgt
     9661 ataaacggta gacaggttgt ccgctgtttg gtgcttgcca agcaatccct tcatattccc
     9721 agcctacagt tggcagataa tttttttctc cggcattcaa tgtatataaa tgttctcctg
     9781 tatgacggtt atacagacga tacatcggag aagttgaagt tggtgctgta tcatactgtg
     9841 tcagattata ggtttcgatt acattgttca atgtagaacc ataattaggc gcagtggcat
     9901 aacgacctgt tagccaagcc gtagcatctt tgtaagagtt cgtattgctt ttccatgcac
     9961 cggaatagta gtaaacgcct ggctgaaaag aagtcgtctt caataccgtt acgttatctt
    10021 gcaatgattc tttgtacgaa ggatattttc taaaagcggc attcaccgta atccattgcc
    10081 cattcacata ttccgaagta ggcatcgtaa cagattggcc attatagctt cctttaatcc
    10141 caaatagatt gtaattaggg gcagaagcca aagtactgtt cccccagcca ctttcaacga
    10201 tggcttgagc aatcatgact gatgcatata agtcattggc acttgccaaa ctttgtgcag
    10261 ttgaggcaat actatcaatg aacgcttgtt gagaattagc agatgagcga gcataaaaag
    10321 catagccagt atagttttcg aattcagaca aatctgcttg atgggtatgt gtcaatgttt
    10381 gcccatctgt caattggttc gtgatttctt ctgcattctc tggattgttc tgagcttctg
    10441 ctgatgtact gtcttcggtt tgtgtttgtt ctgttgtttc agttgttggt tcttcggttg
    10501 aaattgtatt ttctgagaca gtagctgact gcaaagtact ctctgtatcg ttttcaattc
    10561 ctgtttctga agaactcgat gtctgagttg cgacagtttc tgtcgattct tcagctagca
    10621 ctgttgtgtt ggcaactgct agatttccta aaagaataac gctaaataat aaattctttg
    10681 ctttcatctt ttttctcctt tgaattatga aacttttcct aaataacagt gtaactaaaa
    10741 aagtaaaagc aagtcaatgt ccatatttaa ataacatttg tttctttttg ataaatttgc
    10801 tttttctaca taaaaagacg taaatgaaga atattcttct ccattcacgc cttaaattga
    10861 tggtcgtttg aataactatt taacaagtaa ttctctttgg atattatccg ttatggatta
    10921 tacttcctgt gtcgtcggac ggataatcat gttactgaca gacatccggt ctggcgtttc
    10981 tatcgcaaat gctacagcag aagctatatc ttcggaggtc aatccccatt ctttttgcgc
    11041 ttcatgaagt tcaagagcag cctttttgtc gctgatggtt tgatataatt cagtttgaac
    11101 agctcctgga gagatgatcg tagatttgat gttattttgc cgttgctctt gacgtaatcc
    11161 ttccatgatt gcacggacag caaattttgt tccgcaataa acggcggaat caggataaac
    11221 aacatgtccc gccacagaat cagttgaaat gatatgccca gatttttgtt tttccatgat
    11281 tggaagtacg gcggaaattc catttaacac acccatgatg ttgatatcaa gcatattttg
    11341 ccattcatca cggtgacctt caactaatgg agcggttggc atgattcctg cattattgta
    11401 caatacatcg attcgaccga acttttccat cgctaaatcg ataactgctt ggacttgtgc
    11461 aaaatctctt acatctgctg tttgaatata tagctcagct tctggtaaag attcttttat
    11521 tgcttttagg cgatcttctc ggcgtgcagc tataactagt ttagcccctt tttctgctaa
    11581 tagcttcgtt gttgcttcac cgattccgct tgaagcgccc atgatgacaa tcactttttc
    11641 tgataaatca ttcattctat tctcctcctg ttttgaaaaa tctcttgctt atactcacta
    11701 tctcttattt catcttactg ttcaaataat ccgttcgaca ggtttgacga ttttggcagg
    11761 gattcctgca acgatggtat tgtctgggac atctttcgta acagttgcat tcgctgcaac
    11821 aatggcattc tcgccaatcg ttacgcctgg cagaatagtt gctcctgctc cgatccaagc
    11881 atttttcttg atgtggattg gctttactaa caagcctctt cgttcttttg gatcggttag
    11941 atggttcacc gtgatgaggt tgacacgagg accaatcaat actgaatctt ctaaacagat
    12001 gccacctaag tcaacgaaca tcacttgacg attgataaag acatttttcc ctatactaat
    12061 atgtttgccg aaatctgtat aaaaaggcag cagaacagtc accgtatcat ctactttgtc
    12121 actaatgata ttttctagcc gtttgcggat atctgctggt tcatggtacc cagtattcag
    12181 cgctgctaaa ggctcttcgt tttcagcttg gatctgatgg atcacttcaa agagcggatc
    12241 cgttactcga atctctttat tgacgatttg tttttcgatg aggcttgtca ttttgctccc
    12301 tccttttatc cttactttat aacggacggc ttatcatgtc taatacttat aaaacatact
    12361 taactattcc ttttaactat acttagtggt atgctttttt aaaaacagga gggaaaaaat
    12421 ggatattcgt atactgacgt attttttagc agtagctaga gaaaaaaata tcagccgagc
    12481 agcaaaatct ctgcatatca cgcaacctac tctctcaaaa caactgaaag atttagaaga
    12541 agaacttggt gtgacacttt tcactcgggg ctcccgagag atacagttga cggattctgg
    12601 tcgatatctt tattcaaaag gaaaagaaat cttgtcgttg gtagaaaaaa cggcgaacaa
    12661 tttaacaaat gacgcaatca tctctggaga aatctacatt ggcggaggcg aaactaaagc
    12721 aatctctttc atttctgata gccttcattc gttgatcaag gcgcatcctg atatccagtt
    12781 tcatttatat agcgggaatg cagatgatat catagacaaa ctggatagcg gattacttga
    12841 ttttggactc gtaatcgaac cgacaaacaa acaaaaatac cagtcatttc gactgccagc
    12901 ccaagatcgt tggggacttt tgatacatcg aaatcatcct ttagcaaagc aaaccgtcat
    12961 ccatccgcag gaactgaaaa ctgttccttt gatcatttcc cggcaaacgt cagtggacag
    13021 tcaactagct gaatggctag gtttcagcat agatcagtta tcgatcgtcg gaacatataa
    13081 cttattgtac aatgcttctt tgatggtcga taacgggact tttggtgcat tagctctaga
    13141 tgggatcatc aatacttatg ggacggaaaa aatattcatc ccactcgatc cgccattaca
    13201 agcttcactg aatctcattt ggaaaaaaga ccagcctctt tctcctgctg ctcgtaaatt
    13261 tttagatgtc ctaacggaga aatacagtta agtagagttt ttttccttcg ctttcagctt
    13321 tttaacaacg aataagataa gcaaaagatc caacgattaa ataacataag tttcttaatt
    13381 tatttcttcc ttttatttct gataattcca gtaaattact ataattataa aaaaagaatt
    13441 gacaaaacat aactgtctat ataaaattga ttacgttaac aataattcgt ttcatgtgac
    13501 tagatcatac taggcatgaa aaatctctga ggaacatggt ttccctagga ggtttttcgt
    13561 gtctattttt gtttggccgc aatcaactgg tctagcaaac gtgaaaacca aatcttcaaa
    13621 aagggtgcgc gcatgaaaat caaaaagatc tttaatcaaa atgcagtatt ggtagatgac
    13681 ggtggacagg aaaaagtagc tattggaaaa gggattggat ttgacagaaa aagaaatgat
    13741 ttgatttttg atcgtgatgt cgaacggata tttgtcatgg aaccagaagg tcaaatcaag
    13801 ttgcaaaatt tacttaatca gattgatgaa cgctttttat ttgcagcaga aacgatcatt
    13861 gatcatgcgg aaactgtttt gatggaaaag ttgaatgaac atgtattgat cgctttgacc
    13921 gaccacattg ctttttctgc ggagaacatt aataacggta tcgtcatccg caacaaactt
    13981 ttaagagaaa tcgaagtgct ttacagtgat gaattcagta ttgctcaatg ggcagtagag
    14041 tatctgacaa aagagcttgg gattccatat acttatgacg aagcaggata tatcgcaatc
    14101 catattcaca gcggacgaag cggtcggaac aataaccatc gcagtatccg tgaagtgacg
    14161 attgtatctg acatcatcca tttagtggaa tcagaattgg aaacagatat ccattcagaa
    14221 ccattttcac tgaattattc aagactggtg aatcatttac gactgcttct acaacgaacc
    14281 catgcgcaac aatatgctgt tttagacacg gaaatcgtag aaatggtcaa acgaaaatac
    14341 ccagaaagct ataagatttc taaaaaaatc cgtgtgttgc tgaccaaaga ataccagctc
    14401 gcgatcacga aagaagaact gggttacttg gccatccata tcgagcgttt aagaagcgca
    14461 atcgtacaaa caaatgttaa caatcatgag gaggaaaaaa attgaaagca tatctacaac
    14521 gaatgggacg ttcccttcaa cttccagttg cggtcttacc tgctgctgct ttactagtag
    14581 ggatcggaaa ctggtgggca tcttatagta acgacattgt cgctcatttt ttacaagctg
    14641 gcggtaacgc agttttaggt caattacctt tgctgtttgc cgttgggtta gcactaggga
    14701 tgtcagtgga caaatcaggt gctgctgcct tggcaggttt ggtcgcattt gaagttccag
    14761 taaatgtttt aaaaactgat tcagtagcta ctttattgaa tatcaaacca gaatcagttg
    14821 atccatcttt tgctcagatc agtaacgtat ttattggtat tattgccgga ttgattgcgg
    14881 cagctcttta taatcgtttc cacgaagcaa aattaccgat ggctttatct ttctttagcg
    14941 gcaagcgtct agtgccaatc ttggctgcct ttgtcatgtt gctgatcagt gcagtgctac
    15001 tgctcgtatg gcctccggtt tactctgctt tagtttcttt tgctaaattc attttgagtt
    15061 taggctgggg tggtgcaggt ctttatggct tcttcaaccg tttactgatc cctacaggat
    15121 tgcatcaagc aatgaactcc gtgttctggt ttgacgtagc aggaatcaat gatattggta
    15181 aatttttggc ttctgaagga acaaaaggcg taacaggaat gtatcaagct ggatttttcc
    15241 caatcatgat gttcgggctt ccagcaggag catatgctat ttacagaaat gcacgtccag
    15301 aaaacaaagc aaaaacagct tccttgatgc tagcagcagc ttttgcttca ttctttactg
    15361 gtgtgacaga accacttgaa ttttcattta tgttcgttgc ttggccatta tatgtcttgc
    15421 atgcaatttt cactgggatt tctttagcag tgagtgcatt cttccattgg acagcaggat
    15481 ttgcctttag tgccggattt gtcgattact tcctatcttt gaaaaatccg attgcgaatc
    15541 agccattgat gttgatcgtc caaggattag taacagcagt gatttactac tttggcttta
    15601 actttgctat caaaaaattc catctgatga ctcctggccg cgaggaagca gatctttcag
    15661 atgacgatac tgcaacgact aattcagaca ataaatatgc ggcacaagca agcaaaatct
    15721 acgctgcatt aggcggagcc gacaatgtaa cttcgatcga taactgtact acacgccttc
    15781 gtttgcaagt caaagataca ggcctgatcg atcaaaataa aatcaaagcc actggcgtac
    15841 ctggtatgaa gatcatcgac ggaaaaaatg cgcaagtcat cgtaggtaca gaagtacaat
    15901 tcgttgcaga tgagatggca aaactacatg gtggtgctgc agcacgacct gcacaaacaa
    15961 acaccgtggt taaaacagaa acatttgccg gtgaaacgat cgaacaagat atttacgcta
    16021 tcgcaaatgg gaaactgatt ccaatcactg aagtttcaga tgatgtattc gcggaaaaaa
    16081 tgatgggtga cggctatgct gtattaccag aaaatggaga aatcttctct ccaatcgctg
    16141 gtacgatcac aaacattttc ccaacgaaac atgctgtcgg aatccaaaca gatgctggta
    16201 tcgaagtctt gcttcatatg ggcatcaaca ctgttgactt aaaaggcgaa ccattcactt
    16261 tatatgtaga agaaggtcaa aaagtcgcaa gaggtcaatt gattgcttta gttgatcttg
    16321 ccgctattca atctgcaggc aaaaacacgg atatggtcgt tgtattcaca aatggcgaca
    16381 aagtccaaag cttagaaatc gaacccgcac gtgatgtaaa agcaaatgat aaaatcggct
    16441 ctgtttccaa caaagcctga gccatcgtct tccccagact tttttatcga taaacaaaca
    16501 ggagctgaga caaaaatctt gtctcagctc ctttttccga ataaaaacgg cgttctcctg
    16561 ccaactccgc ggtaataagt ccagctaaac gaaacatatg aagagctatt ttttatttga
    16621 ctcttcttat tacttgatgc agaacagctt tttcacaaaa tttttcttca tactcaaaac
    16681 taatcggctt tttcacaacc tctttataca ttattcctga tccaatattt cttttaatgc
    16741 tgcttcaaga gaagttaatg gttttcccaa tactttttct aaatcatcag aggaaatagc
    16801 taactgatcc tttttaatat catgttggat cgctaaaaac atgtcagctg cttcttgagg
    16861 gaatccggct tcttttagat tttcgacaaa cgctgcatca cttgcttcaa taatttctaa
    16921 ctctttacct gtcgcacgct ctaatgcctt ggctaattct tcatagtcag ttagattgcc
    16981 ggataattct aagatttctg gagagtcact ttctactagt acttttgctg cagcttctgc
    17041 atattcacgt ttcaatgccc aacctgtttt tccatttcct gcagcataaa cgaattgacc
    17101 agtttttaaa gcctgcccaa tgataggtaa ttcattctct acataccaat tattccgtaa
    17161 aaatgtatgg gaaatacctg aatccttaat cattttttca gtgaattggt gatctggcgc
    17221 taatacactg atcgagtgat cggcatctgc aaaacttgta taagcgatat aagatacccc
    17281 agctgcttgt gctgccttca ctacattctt atgttcggct tgacgatttc ctggaacgcc
    17341 agagacaaaa agcaatcgat ctattccttt caacgcttct ttcattgagt ctaaatcatc
    17401 ataatcacca atacgtatat taaatccagc ttctttcagt gcttctcctt tttcttcact
    17461 acgtactagt acatagattt cattttgtgg aaccatcttt tttaagaatt ccagcgcata
    17521 accaccaaaa cctccagttg ctcctgttac taaataatgc atatttgcca ctccctattc
    17581 tttttatttg ttaagattta cagctgtaca tttataaatt acacctttat cataaagagt
    17641 gtggtaagat aagtcaagca aaaaaaatga aaggatgaca actgatgaag tattctctgc
    17701 aatttagtga tgcaatccat gtacttgcct atattgaaat gtttcaagat acccgatcac
    17761 tttctagtga gatgattgcc agtagtatcg aaacaaatgc agcaaatgta cgtaaaatca
    17821 tgagtcagct caaaaaatcc ggtttgatct ttacaaaaac cggaaaaccg cagccttccc
    17881 ttgccaaaag tccagatcag atttctttac tagatgtcta tcgcagcatc gaaggtaata
    17941 cacagcttat ccaagtcgat ccaaaaacaa atccaaattg cgtcgttggt gcgaatatcc
    18001 aagaagcttt agaagaaagc tacgctcggc tgcagaaaaa ggcagaagaa gaaatggcta
    18061 agatcacact tgatagtctg atacataaaa tagccgtttt ggaaaaagaa aaaagaccag
    18121 aaaacacagg cctcgtagag agatttttat aattctctct actgtgcctg catttttctg
    18181 atcggaatcg tctacataaa ttcttttatt ctccggggga caaaagcctt gtcatgcccc
    18241 tttttcctct ctaatgctca ggtcaaagcg ctgaagtcat gacgtcttga taaacggtgt
    18301 tcaagtagct gaccctcggc attagttctg aaaaatgcaa aatatggaaa gctatttccc
    18361 atttttcctc tctaatgctc aggtcaaagc gctactttca cgacctctat attatcatgg
    18421 tttattgact accggtatcc agatttctcc catatatttc ccgttggtaa ctcccatttc
    18481 gactacagca tttggacccc caacataggc gtaatcttct acttctctta aaacatgccc
    18541 aaaggccgta ttcgtcaaat catttcttaa ttcttcaggc gattctgcta aagcgcttac
    18601 aacaagatac gttccttttg ggaatgggat gattcgcgta gtgtttggaa catcctgact
    18661 cgtttgaaca ccgacatagt acatcatttt cccgttatag ggttcgttga ctgtaaagaa
    18721 ataatgattt tcagcagctt gtttcaatgc atctattgtt ccattaccga taactttttg
    18781 ctcaaatgct tgtttctctg cagccaaacc gacaaaatcc gtattgctac tcttcaattc
    18841 cacaccaata cccgtcaccg taaaatctgg tttttcttcg atcctatact ttgccatttc
    18901 tcccaccctt tctattatat taagttcatc ttacataaaa ttaaagggaa atgacacgat
    18961 tacgctcttt tttctaggga tatttttatt ttttaactat ttttttgctt tcactgcaat
    19021 ccaaatctca ctgtaaacat tactgaaatc ctctccccat tttgtaaaag agatctcggg
    19081 agcttcgact aacccataat ctgaagaagg aagccattct gcatagattt tcccccaagt
    19141 atcttgtaaa gtttggggaa atggcccttt attaggaaaa atggcccaag tgtgttcttc
    19201 tatagcaagc atttctaaat cagcgtacgg attttctttt gtcgtagcaa agccaatcat
    19261 gtgcatcaaa ctgccctttt cttccaagcg gtctccatca aatccataag aaacgttgat
    19321 tacttgattt ggatataaat ctcctaactt atgcatctct tccctttgag tctccgtgat
    19381 cgtctgcgct aacttttgta tttcttgatt gactccttca aatttgacag gaactttttt
    19441 cgccacacct gccacataaa actgttcttt cttttcgata cgaaattcca tcgattttcc
    19501 tcctctgaca tcaataaaaa atgtcaagcg tggaaaagat ttttgtatgc cgtatctgct
    19561 gatttctgaa ggcagatatc ctgaccaatc acgaaaagct cttgaaaaac cttcgactgt
    19621 ttcatatcca tatctaaacg ccgtttctgt cactcttgat ccatctagaa gatcgcgatt
    19681 agccaaagcc aatctacggt ttttgatata gtccattagc gacatccctg caataaacgt
    19741 aaagatgcgt tttaattgat attcagagat tcctgtattt tcggctatta ttttatagga
    19801 aagtccttct gtcaaatgtt cttcgatgta atcgatcaat tggttcagat ctttaagcat
    19861 atttatcttc ctccttgatt gcctttttat catattatca aagaaagtca attacttgat
    19921 gaatcaggaa ccaatttagt cagatgtaga aaatgttgta tggatctaaa gaaaattctc
    19981 aagcagcgtt tcgtaacgga taattggtat tatctgccta tctatgtttt acctttagaa
    20041 aaataaattt tggggaagac agattctaag taaacaaagc ggtaaaaata tcttttattc
    20101 ccttagttaa tccgcttact acctactgta caaagcaaat tgttgttcaa actgctgatc
    20161 agaacgctgc ttggattttt ctttgcagtc aagtccacaa tcttgtgtaa aagttcaacc
    20221 tcatcaaaag cacaatgttt tgcgttgtga acctaactgc catgcctttc tttctgagga
    20281 gagaggtcag gagcagtagc gcagcgactc ttgatgtctc tcctcagaaa gaagagactc
    20341 gcacaggttc atggtgctaa atgttattcg aattaaattc taaatatttt cgtggagaag
    20401 ccagccactc agtgtctttt tccatcaaaa gtgttccaat tatccgagtg atggaattga
    20461 tatttggaaa aatccgaatc actcgttctc tccggcgaat ctcttcgttc aaccgttcca
    20521 acacattggt tgtacgaatc cttcggcgga tattttcagg aaaagacaaa atttgaatag
    20581 catcttcaaa gccgttttct aaaatgtcgc aagcagcact taattttgaa tcacaaccat
    20641 atttttccaa gaagtgctct tttctttcac gtgtcaattc aagttcagag gctttaaaga
    20701 tactcttcaa ctcgtctttt acatcagaag aaactttctt tggcagctta tcaaaaatat
    20761 ttctcaaaaa gtgggcttgg catctttgcc agctcgcacc taaaaagttc ttgcgaacag
    20821 ccttaactaa ccctttgtgt gcatcagaaa tgaccagttt tacaccgaac aaacctcgtt
    20881 gaacgaacga ttgaaaaacg gtatcccaat tatcttccga ttcgccgtct tgaacatcaa
    20941 aaccaagaat cgtacgtcgt ccatcagaat caatgccgat accaatatat acaccttttg
    21001 agacaatacg atgattttcc cttactttca tatacagggc atcacacatg aaaaatggat
    21061 attccgagcc ttctaggctc cggtttctcc actcaaaaac aaatggatcc aactgtttca
    21121 tcagatttga aacgaatgat ttagaaacag tcgcaccatc cgttagcagt tcaactgttt
    21181 tagttacttt gcgagtggag acaccagaaa tgaccatttc aatcatggca gcgatcaaag
    21241 ctttttcgct tcgctgatat ctttcaaaga tagtaggact aaacttaccg tctctggttc
    21301 gtggaacatg aagttctaac gtaccaattc gagttgtaaa cgaacgatcg tagtaaccat
    21361 ttctttgtga ttgccgttct tctgaacgtt cataggcatt tgcctgaata tattgatttc
    21421 gttgttcttc catcagctga ttaaacatga tagtcataag tgtttttgcg gtatcattcg
    21481 caccgctttc gtttataatt gcttgaattt cttcgctttc aaaagtaaaa tgtacttgag
    21541 tcattgatat cagtcctatt cgagtatgtt ttctgcaaaa aacattgtac tcctaactga
    21601 gatcaatggc ttttttgatg cttcactttt acacaattat atggacgtaa tcttctttgc
    21661 gatacatcat acctctttta tcaattggaa caattattta tttctaacaa aatcacttca
    21721 tttttgtcag ataaataaaa aacaaaaaaa gttccatctt taaaacacgc tattctttta
    21781 ctttttctca cattctctaa gaaaagaaaa ggagaatgaa tttttgacaa ttcgagcaaa
    21841 agtgattatc aaatatgtaa aatcagctac ttttttctta aacgtttctt tatactaaat
    21901 ataaataagt gtttcatgaa aggagaacta gatgaataat tggcttgagt attttcctga
    21961 aaacgttttg gaacgcggtt acagctatca tctgcacggt tttgtccgtc atttgaacta
    22021 tacaagcaag tacttgtccg caacagtttc tggcacggaa gattataagg tagtgatcac
    22081 ttgggatgaa aagaccaaca tgacttgtga ttgtctatat gccatagaag gaaaaaaatg
    22141 caaacacatg gctgctgtct tattcgctta cgaagaacgt ccaataaaaa aatccaacta
    22201 ctcactttcc gaactctcgt cccttgtttc ctccgctagt tcctctcttg tacgggagct
    22261 tttaacagag attcttatag aacatccgca ctttatcgaa cgcttcaaag ttaagatgcc
    22321 atttcatgca ataaattatt cagataaatt aacaactatc atccataaat acgatcatat
    22381 tatcaagaaa aacaaaaaca ggaaaacagc gaagttcatc atggagatgc gaaagttcat
    22441 ccaagaagca gttgaatcgc ttattcagca aaatgcctat cttcccgcat tcgaattgat
    22501 caatgaagtg attgctactc tcgaaacatt ctattgggag cctgaggatg aacgaaccct
    22561 tcttctgata gaggactgtt attatttatg gaaagaatta ttagcagaag cacctcatgc
    22621 agaaaaaagg caaatgttct cttggttcgt ctgccaagtc gatcatactg acgcctctta
    22681 ttcaaaacgc tactctataa aaatcctgaa agaagacttt cgggaaaaag aattttctaa
    22741 ccaaaagaaa aaaatagata aaaaactaaa gaaacggtaa agaaagacga tttcaatgaa
    22801 aaatagcaag taaacgataa caaccatcct aaatccacaa gaaatacagc agaccttgct
    22861 ttaaaaacac gaatcatgca aaggatgaag taaagaagac ttaacgcgta cccaatatta
    22921 gtcatttgac tattaggtac gcgttttgtt ttataagtca tgacaaattt ccttcgttgc
    22981 tggatagatt ttccggcatt gttgatagat tttatgatac ttttctacat tttgtaagag
    23041 aggttccact gcatctgtat attggataaa attctgacaa caactttcag gtgtgtcgaa
    23101 ccaccctaac cctagtgcag caatcattgt tgcgcctaat gcaggtcctt cctccacact
    23161 taaacaatag accgttgcat cgaaaatatc agcttggatt tgtagccatg caagattttt
    23221 cgcgcctcct cccaccgaaa caatacgtgt aaatctgcga cccgctagtt ctttacgttt
    23281 caatcccacc attgacaaat gctcattaaa aatttagaat attcacaagt ttaacgacaa
    23341 ttatgaaaat ttatgtcgtg ctaaaggagt tttgttattg gatgaaaagt tagatataaa
    23401 aactgcgatc aaagacacgt tacctaccgt tttcggttat atcggtattg gacttgcatt
    23461 tggtatcgtt gggaaagctg ccggatttca tccactagtc gtcacgttga tgtccctgct
    23521 ggtctatgct ggttctgccc aatttatcac agtcagcatg cttgctagtc acagcccatt
    23581 gctttccatc gttttctcga cctttctagt caattcccga atgattctga tgagtatgac
    23641 gattgctcct tatttcaaga aaaatcggct gcttcaaaat ctgctgattg gcacattgct
    23701 gacagatgaa agtttcgcac tgggaatgaa taaattgaac tatactggac aaaagttaaa
    23761 ctttcgttgg atgaatacag ctaattggat ttcttatttg acgtgggtgg gttcttctct
    23821 tgttggcgca cttttaggga attttattac tgatccgaaa aagtttggtt tggatttcgc
    23881 catcgtcgct atgtttatcg ggttacttta tcttcaagtc atttctgata gaaacacctc
    23941 taaacgatta cagttgatcc tgattggtct cactttgatt ctggtatatg tcggactgat
    24001 ttttatccca agcaacttag tgattgtagt tgtaacactg attgggtgcg gattgggggt
    24061 gtggatcaaa catgccttct tttgagttta cattgctgac tattttaggt tgtactttag
    24121 caacttggct ttctagggtc ctaccatttg tcttactgaa aaaattcgat ttaccgcaac
    24181 cgttgcttga gtatttaagt tttgtcccga tcgtcattat gtctgcttta tggttcagca
    24241 gtctatttac ccaaaatatc ggacatctgc cgcagatcaa tctcgaaaat gctttggctt
    24301 cagttcctac acttttagct gctattcttt caaaaagctt attggtgatc gtcttggcag
    24361 gaattctttc cctttcgttg attcgcttat tataaataaa aaaacaagag cttatggcaa
    24421 attactgtca tgcgctcttg tttttatcaa agtcaaataa gaaaaaaatc ggcgtattct
    24481 tgcttatccg ttgaacggac cactaacaac gacttttcct aacatatgtc ctgtttctac
    24541 gtctttggtt gcttgtttca agttcttcgc attcatccca tctgaataga ccttgctcaa
    24601 tgtactgcgg ataatccctt catttgctaa agcagcaatg tgcgctaaag cttctccttg
    24661 cgtttcgatt tcatagttat agtctgtttt agcgaacata tactcccagt cgaagctgat
    24721 agattggttt ttccaaacac ctatatctaa cggctctttg atccctacga tcgttcccac
    24781 atgtccaaat ggtcggacaa ggtgcttgat ttgatcaaag tagcgggtaa tatcgaataa
    24841 tacagcgaca tactctactt gatcgattcc taattcacga aaacttttac ttaagtcgtg
    24901 atgataatcg attggatagt ctacacctgt ttttttcagc cattcaaaat tcttcggact
    24961 tgcagtcgcg tagacttcta ggccagccca atgcgctagt tgattcaaaa tcgaaccgac
    25021 gcccccggat ccgttgatca ctaagatttt tttcccgcga ttggcatttt cttctggagt
    25081 tagaccaaat ttttcaaata acaattcata agcggtcaat gaggtcaacg gcaaggctgc
    25141 agcttcttca tctgaaagat tttttggtgc aagagcgaca atacgttcgt caactagttg
    25201 gtattcttga ttgcttcctg ctcttgttgt tgtacctgcg taaaaaacgc gatcgccgac
    25261 agaaaatttt tgcacttcgt cacctacagc aacaactttc ccgactccat caaaacctaa
    25321 gatacgtaaa gcatttctta tcccgttatc ttggcgaagt ttcgtatcga caggattaac
    25381 agatactgcg ttgactttta ccagaagatc ccgtgaactg ggtacaggta tctgttcttt
    25441 ttcatcaata aagctttttg gatcatcgat cggcaaccct tcataaaaac cgactacctt
    25501 cattaattcc ttttctgaca tacgaattcc tccttagctt catcaagttg gagcatccat
    25561 acagtgttca tttcaatata tatagtatgc tatttgttcc acctttttta ttcatcataa
    25621 ttattctctt acttaaagta aactatttgc acttttttgg ttaaaaaaga ggttgcgaca
    25681 agacttttgt cacaacctct tataaacggt gttctcctac caactcttcg gtcacaagtc
    25741 aaaatattca tcaaacatga gaagctgttt tttgaaattg ctccttgtga ctcagagtta
    25801 aacggcaggc tcacaacctc tgatataaac ggtgttcaat caactgaccc tcggtattag
    25861 ctcaaaaaac gacaaaatat gaagagctat ttttgtttgg ctgttcttat tacttgatac
    25921 aggacagctt tttcacgacc tctaattcac ggtgttcaag caagaaatca ttgttcactg
    25981 aaaagcgttg gatgttcttt ttcaaaggtc tctaagatct ctcgtacttc atcagtagat
    26041 ttcgtattca tcaactgaac tcgcaagtca tttgctcctg gaaatccttt gatatagatt
    26101 ttaaagaaac gatgtagtcc tgtgatggaa cgcgggatga tttctgaata atgatcttgc
    26161 agatctagtt gcagacgaag tagtccgatc agttcttttt ctgtatgttc cctcgggtct
    26221 ttttcaaatg cataaggatt cttgaaaatc cctcggccaa tcatgatgcc atcaacgcca
    26281 tatttctcgg ccaattcttc tcctgtctgg cgatcgggga tatctccatt gatcgtgatt
    26341 agtgtttgtg gagcgatttg gtcacgtaaa gcaatgattt taggaatgac ttcccaatgt
    26401 gcatctactt tactcatctc tttacgcgta cgcaaatgga cagaaagatt ggctatatct
    26461 tgatgaagta ggtgactgat ccattcttcc atctcagaca tttccgtata gccgatacgc
    26521 gtcttgacgc tgacaggcaa accgccagct ttagctgctt caatcaattg tgccgctact
    26581 tctggacgaa ggatcaagcc actgcctttt ccacgttctg ctacattagg gactgggcag
    26641 cccatgttga tatcgattcc ttggaagccc atttctgcca tagcaatgct catttctcta
    26701 aaaaattctg gcttgtctcc ccaaatatgg gcaaccatcg gctgttcatc ttctgtaaat
    26761 gttaatcttc ctcgtacact gtcttttcca tctggatgac agaaactgtc tgagtttgta
    26821 aactcagtaa agaagacatc cggtgctgct gcatgcttta cgacatggcg aaatacaaca
    26881 tctgttacat cttccattgg tgctaaaaca aaaaaaggct ttggcagctc tttccaaaaa
    26941 ttagtagtca tttatttgtt actctccatt ctatcaagca gtgaagtcgc aatctttctc
    27001 aaaaacattg tcattatact aggaaacaaa aaaagaagca aagtgaacag cttaaaagat
    27061 gtttctgatt gagcaaaaaa aagactgtga caaaaatctt atcacagtcc attttccgga
    27121 ataaatggtg ttcaaaagct tgcatctgcg gtaataagtc caaccaaacg aaaaatagga
    27181 ggagctattt ttgtttggct gttcttatta cttgatgcag aacagctttt tcacaacctc
    27241 tccactaaac ggtgttcaat cagctgaccc tcggtattcg ctcaaaaaac aacaaaatat
    27301 gaggaactat tttcccgttt gtttctctaa tactcaggtc aaaacgctga tttcacaacc
    27361 tcttttctaa cttctcaatc ctcttccttt attgatcaaa taccaagtaa cggcgtacaa
    27421 aacaacgatg aataacacaa gtacgatcat cgatgttgct actggcacat cgatcgttcc
    27481 aaggaatccg taacggaaac cggagatcat ataaacgatc ggattgactt ttgaaacagc
    27541 ttgccaaaag ggcggtaaca tagagatggc atagaaaacg ccacctagat aagttaacgg
    27601 ctgcaagaca aatgtaggca cgatcgatac atcatcataa gactgagcaa aaatcccgtt
    27661 gagcagtcct gctaatgaaa acaagattgc cgtcatcaat aatgtaatga tgaccatgaa
    27721 ccatgaatac acatgaagtg gtacaaagaa caaggaaatg atcgttacga gagagccgac
    27781 gagaatactg cgacccacac caccaatcac aaagccccaa ataatcacat gcgtaggaac
    27841 aggtgctacc aagatttctt cgatattttt ctgaaatttt tgagagaaga aggacgaaga
    27901 aacattggca tacgaactag tgatagcaga catcataatc aaaccaggaa cgatgaattc
    27961 catatatgaa aaaccaccca tgtcaccgat ccgcccaccg atcatttttc cgaaaataac
    28021 aaaatacaag gatgtcgtga tcactggcgg aaccagtgtt tggacccata tacgcaaata
    28081 gcggttcgtt tccttgatag ctaaactttt taatgcagta aaataaagat taaacatttt
    28141 tctcctccgt atgattattt tcttctgtga ttttcaagaa cagttcttct aaacgattcg
    28201 acttattcct catagaaaga actttgattc cttgtcttgt aagctgatcg aagattccgt
    28261 tcaccccttg atttcgttca acttcgacag cgattgtctg ctcatcttca aatgtacaag
    28321 catatccttc aatcacaggt ttggtatcat atggcgctaa atcaaagata aatgtttcaa
    28381 attgcagttt tgacagaagc tctttcatac ttgtattctc gatcagttca cccgattgga
    28441 tgattccgat gttgcgacaa agcatttcag cttcttctag ataatgcgtc gtcaaaatga
    28501 tcgttgtacc attttcgttc aattctcgta gaaactccca catctcgcgt ctcaactcga
    28561 tgtcaactcc tgctgttggt tcatccaaga tcagcaaacg tggttcatgc atcaatgccc
    28621 tagcaatcat cagtcttcgc ttcattcccc cggaaagcat acgtgcacgg acatttctct
    28681 tttcccaaag attggactgc ttcaaatatt tttcgctgcg tttcatcgct tctttgcgag
    28741 agacaccgta gtagcctgct tgattcacga cgatttgctg gaccgtttca aaagggttaa
    28801 aattgaactc ttgtggaacc aatccaatct gttgctttgc tcgaactaga tccttgtcca
    28861 gatcataacc gaagacattc acttttccag atgttttatt gactaaagaa gtaataatcc
    28921 cgatcgttgt agacttccca gctccatttg gccctaatag cgcatagaaa tctccttctt
    28981 tcaccgaaag atcgattccc cgcaatgctt cgaccccact tccatagatc tttttcaaat
    29041 tatttatttc aagcgcattt gccatttatt tcctatctcc ttatagacat gattcttaat
    29101 tgtatcatgg aatacagcag atgaaaaaac aacttggctt ccacacaaaa acacacctgc
    29161 taacaaagag gagatgtgtt ttctagttca tgatcatctt cgatagaata actatctaaa
    29221 caactctgga acttttaaaa tcataaaagt accgacagca actactacga tgacatatag
    29281 aagatcctta taactgaggt tcttgtcttt tttattcatg ttaagctttc ctccgtcctt
    29341 ttatcgaaag cttttttctt ttattttaac cgaaataaat aaaatggaaa tagttatttt
    29401 caatttctgt tttcgctgtt tgttttacgg agaactttgc catggaacgt gcgtctcgtc
    29461 gctgatgcta agttttttcg ataaaagctg ctagaaggaa gacagcgtgg tttattttgt
    29521 atcgtctttt gctaaatctt ccaagatcat ctggacagca gactcgttcc cattgaattc
    29581 tgccactttt ttggcatcaa tgtacttctt ttgataatcg tctttttgga cccacgcatc
    29641 atgcttcgtt tgataaagtt aatcaaacgg ataccactga cgctgttcat cgaacaacaa
    29701 actttctttt tgggcctgtt caactatgga tttaggataa ttcaaaactt tcagcaaggc
    29761 aatcgcattt cgggtccttg aaggtccttc ttttaatttg aaatcaaaac tgattccttt
    29821 tccttctgtt acttgttctt caaagtggac attctcacaa taattcttta aaatctctgt
    29881 caattcgata tcatgtgtgg cgacaaatgc taaagatgga tactccgcaa gccaccgaac
    29941 gactgaagcg gaagaagcaa tccgttcgat cgtatttgtt ccttttaaaa tctcatctac
    30001 gaagcagtag cagcgttctt tggaagccac ttggtccagc aaacgtttga tcgatttgat
    30061 ttctgaaaca aaataactgt cgccttcaaa taaatcatct tcgattgcca tggaagtcaa
    30121 cacatgtcca ggttgcaggg taaactgttc tgcaatcgct gtttggatcg tctgtgctag
    30181 aatacagctg atggctatac ttttgacata cgtagatttt cctgatgcat tggaacccgt
    30241 gactaatgta ttcttctgcc agttgactgg attaactacc gcttctttta acaatggatg
    30301 atagatatct ttcgctgtca caccgccctc agtaaactct ggtcggcaag tgatcggcat
    30361 ataggtgcga taattcaaaa cggctgctgc aacttccaat tctcccagca attcccacag
    30421 cttgatggct tcagttgaat gcttttctaa tttagtgaga acgaaatgat aggagataaa
    30481 tggcagcatg aacatgatgt tgacatattc aaaaatcaat tctgcttcac tcccgctctt
    30541 cattcgaaat gaaaaaccta atttagggat gtctcttaat ggtttagttt gctgtttcag
    30601 ctctttttga agtggtgtcg tcatttttgc taactgattg gcggctgaaa tcgttgaaac
    30661 caaataactc atgctattca gctctgtttc tagtgtttgt ttcttcacta gataatagac
    30721 cgtattgaat actaagccac cgattgctag atagattcct agtacttgcc ctaaaagaag
    30781 caaacctaca cccaccagcg gaagcaagcc aagaaaaata aataaaccta cgcgtccaat
    30841 ctttttactt tttccatccg ctagatattg ttttgcaaaa ttatgatctt tttttcctaa
    30901 acgagcgaat tgatattgga ttctttctct cagttgagga ttttcctgat aaaaagcaat
    30961 tagtttttct aactgataat cttctccaaa atcaaagcta cgtaaacgct gatacaacgc
    31021 ttctgaacct acactagaat aggtactgtt gatcccttca aatacttcga acatatccaa
    31081 gtcataccaa gtaagatcgt cgatttcact atcccatgaa cggaattttt tctccgtgag
    31141 ccacgcatcc ttcaaacttt cttctttatc aaatctcggt tgataaggaa tttttcccca
    31201 attactacga actgtttcct ttactttcaa acgtgaaaaa atgtctaaaa caactaataa
    31261 aataacaact gcaataataa ttaaaacgat aaattctctt tggcccatat ccctctccgt
    31321 tccttgattt gttagtttta gtatagcact gttgcgctat ttgaaaaggg ggtacaaaaa
    31381 taactgtctt cgttacctaa ttcgtatcaa tcacaccaaa ataaaaacac cttccaaaaa
    31441 agaagatgtc tttaaaacga gatacaattt tttgtcattc acttcaggta aattagagcc
    31501 aattaaaccc tccgcaactt gacggagatg gagaagatgc ccccgtctaa tctagcggtc
    31561 atctctcctc ccattccttc caccaatttt tttgacaggt aaagcccgat tccgctagat
    31621 tccgtatttg tgcggctggt attttcggta taaaaacgct ggaagacttt ttcaacagag
    31681 gtttgcgctc ctggtttgat aggattggcc actgttaatc gaatgaatga atcctctttt
    31741 gaaaatgtca cctttgcttg tccatctgca taacgcaata aattctgtat gatattttgc
    31801 agcactcgca gcaacatgag cggatctgct aatacagttg tatttatcga gtgttcagcg
    31861 aacgctacct cgatattttt ctcagaaaat tgttcataaa aagagaaaaa tacttcttcc
    31921 acctctttag aaaaagaaag cgtatggaga tccatttctt tttgcttcgt ctctattcga
    31981 gcaagatcat aaaactgatc cgtcatactg agtaatcttg caacagattg tttgatgatc
    32041 gttaaatact tctcccgttt ctccgtatcc tctacctgtt ccagtaattg tacataaccg
    32101 ttaatagcag tcaaaggagt tctgagatca tgagaaaggc cgacgatcga tagtctgatg
    32161 ttttcttcca tttcttgaaa tgcttgtcct ttttgttcat tttcatccac ccatgtattc
    32221 agtgcatcta ctaggtccat tagattcttt tctcgaaatt cgactgaaag acgaccacca
    32281 tattcttgtc gttcagaaag agtggcgatt ttcttagtta atctcttgat ttccctttgc
    32341 aggaagaaaa taaaacttcc cataaagata acaacgagaa gcaacagcca cttaatcaaa
    32401 tctaaacccc actccccaca ccgtatgaat atacacagca tgtgcctttg ctagtttccc
    32461 tcgaagattg gaaatatgca tattcactgt tttctcacta tcaaaatatg gttcttgcca
    32521 aactgtttca taaagatttg ctcgcgaaaa tacttttttc ggatgttcta aaaaaagctt
    32581 cagcagatcg aattctcttc ctgtcaaatg gacagccaca ccattcacat ttacatccct
    32641 cgactctttg tccagtaaga tttccttgta atagatgcgt tgcgacagat cttttacttg
    32701 gacagaagtc tgatgacgaa gttggatgcc gattcgtaac aacagttctt cgatatcaaa
    32761 tggtttcgtc acatagtcat ccgctcctgc tgccaacaag gaaactttat ctctttgatc
    32821 gctttttgct gaaagaacga tgatcggaac attcgatgtc tgtcggattt ctgctaacaa
    32881 tgcttcacct gaaagccctg gaagcatgag atctagaagg atcaaatcga caggatatgt
    32941 gcttaacaat aattttcctt ccgtacctga ataagcatca agaagtttgt atctctgttc
    33001 aagaacctcc tccagtaaag aatgaacagc ttcatcgtct tcgataatca aaatagtttc
    33061 cagcaggaac acctacttaa tgtcagattt ttggaaaata aacattccta gagctgatga
    33121 taccacgatt gttactagac tgaccagaat cattttcggt gcttgcgaat aagttgcttg
    33181 ttgcgcaaag tccgtataca tgagccacgt ttccgtaaac cactccgtta gaaattccaa
    33241 gcctttgatt tttgcgaaaa caccgggaac gaaggccgtt cccatgatat aaagaaaaga
    33301 aagaagcaaa ctgacactgg tacttctagt gatgaatgtc aaagccactg gaacagataa
    33361 tgtcgctaat atcagcagaa gcaatacagg aaatactttt agaacataat ttccatagtt
    33421 tttgattccc tcaacttcac caaatccgaa agcaagtgtg taagcaatca tggctagccc
    33481 cgtaatcaaa accacgccaa gtgttgtgat caaaagcgta acgagaagtt tcgacacata
    33541 ataagtcatt cgattccgtc ctaaagataa cgtattgcga atcgtaccgt tttgaaattc
    33601 ttccccaata taaaagcacg caaatgctgc gaaagccaga agaatccatg cagccatttt
    33661 ttccaccatt aaaatccctg ttgcaccgtt gatgactgta tccgttgctt ggtttaattc
    33721 attgccgtat tttgtatgca tataccattc gttccaagaa taaaaaagcg gaagtacgac
    33781 catcagtcct agtgagaccc acattttacg gctcttccat acttttattt tttcagcagt
    33841 taatagatta aacatgtgga ttgcctccag ttaattgtaa gaaataatct tccagttttt
    33901 gcccaactag gtggatacca tccacaggaa cttttgcctc taccaatgct tgattgatgg
    33961 ctgctacttg gtcaattcct tcaaaaagct ggataacacg gctagattgg acaaaataat
    34021 ccctataacc aagagagtcg agaaccgtta ctgcttgttc cgtcgccgaa gtgtcaattt
    34081 ttataaattg acgagattct tgtgccaatt cttctttcga taattctttg atcaagtgtc
    34141 cttcatgcaa aataccgtag tgagtggcga tctgtgacaa ttcatctagc aagtggctag
    34201 aaagcaagac ggtgatgccc cgttctttta ccaaacgttg gatgatttct cgcatttctg
    34261 ccatccctgc tggatccatc ccattcgtcg gttcatccaa aatcaaaaat tctggattcg
    34321 tgatcagtgc atttgcaata gctaaacgct ggcgcatacc taaagagaaa ttctttgctt
    34381 tctttttccc tgtattttcc aatcgcatca ttttcagcag gtcttcgatt tctctatccg
    34441 acacaccgcc gttcgctgct tggatacgta ggttatctct tgcagttaat tctggataaa
    34501 gagcaggggt ttcaatcgat tgacccatac gtcgtcttgc tgcctgcaaa tccgtcgttc
    34561 caaataattc gatcgaacct tcatcaatcg agatcaaacc cataatagtt ctcataaagg
    34621 tagacttacc cgctccattc tccccaatca aaccatagat cattccacgt ttgatttcga
    34681 tcgatacttt atctaatgct ttggcagcac cgtatttttt ggttatacca gttgctttca
    34741 agaccgtttc atttccaaaa tccatactta tccttctttc ttattgataa gtgaagtata
    34801 gttgacgggt ataaagaaag cagccagaaa tgtataaaga aagtgtaaat tttccaattg
    34861 aatttcaaga aaaatcagac tgtctcgcag acgtggttga gttgtctgcc aatcaaagag
    34921 cgcaccaaac agtgctaatc caagtggact ggccaccatg gtaatcgttg ttatcgttga
    34981 catcagacgt ccttgtatat gcgttggaac ttctcgctga agccagacca tataaaaagc
    35041 aaaagaaaac attaatcctt aaaaacggac ttatgaaaaa taatacatgc cgtttgggat
    35101 ttacaattag ctaccaaata agaggttatg acaaaagact tttcacaatc ccttcttccg
    35161 aataaacggt gttctcctgc caactcctcg gtcacaagtc acaatattta tcaaacatga
    35221 gaagcaattt ttgtaaattc cttcttattt cttgaagctg accacttctg tcacaacctc
    35281 agaagcggat aaataatatt gtttgatgat actttatctt tttcccgttt gtttatagat
    35341 cgaatgatat tatagaccaa gaatcctacc tattaacata gctaaaaaca caaaaaaggc
    35401 actttccaaa ttgtggaaag tgccagaaaa gttaggatta aggtaactgc gctcagcatt
    35461 gcttcgccca gtacgattct cgtaactcgt gaactcgaac gataatcgca attaacgttt
    35521 tgagaactgt gaagctttac gggctttctt aagacctggt taaacaaaac tctattttat
    35581 tgcattttac aggaatgtat ttcatgcgaa attaataagt ctttgtttat agagttttac
    35641 tagggtataa aaagttgtat gttatcatta cctcaaaaca ttacctcagc ttggcgagtt
    35701 ggttgattga agaataaatc atttatctag atatctcaat aaaaaatgat ttctaagaaa
    35761 cttgtatttt cgtgttatta tttttttgcc ctatcaaaat ttctaattct tctagcgtaa
    35821 tatgattatg acacataatc gattcaatta cttcaatacc tatttttttc gagaaagatc
    35881 ccttttgttc actcacaaaa atactttcag aagacatata taaggaacga agttttggaa
    35941 ttagtatatc gtacaaatag accaccataa aatcgtcctt gcaaccattc tcaaaaagaa
    36001 ttaaatttgc tgattgtgtt acatatatca ctgaattaca ttcatggtca attccaaaaa
    36061 caatgtctac ttcattttct tttctaattc gcgcagttac atttttcaaa ctttcaccat
    36121 tacttataaa tgctttagtt actgtaagct ctgatgtttg ttcagatatt ccttttataa
    36181 tattttgttc atcagccaca ttccccataa atccgccgat tccttttaag taataattct
    36241 cacctaagag tcgcttgcat tcactgaatt gataaaaaaa ccagttaaaa aaatcttctg
    36301 gaaaaataaa ttctgatcga actttattta tatttttagc tcctattaat tttataactc
    36361 gattaatgtt cacttgctgc gatgaacata taactgaata aattgagttg tttaattcaa
    36421 aaaaacaact ttaacatatg catcattaat tcgttatttt ttaggtagat attgatcatt
    36481 gttatctctc tttttttgct tcccatactc caacttagaa attgccgtta taaaatttat
    36541 tttaaaggtg actttttccc ctgaagtatc ggtagtagga atacttaata cctcagcttc
    36601 tgaggaggta tcccaattat agttatactt tgcatcatca ccataaagaa caattccatt
    36661 ttttttatct tgtgccgtta gctttactgg ttcgcttact tttcttgtta atatcttgga
    36721 ctttacatca tcgatattgc ttattttatc aagcttaaat aatttacaaa ttaatttcgt
    36781 actagttttt atatttgacg agagtgtaaa atattttgtg taaatagaaa aaaggaagtc
    36841 ccttctgtag aatagagtta ccacaacaca ttcacagaaa agaggacttc catatgaacg
    36901 attttactac agaaattcta aagactctag cgaacaaagg cgatttgaat gaattattcc
    36961 gtgtccattt ggaaaaagct gtcaatacgc ttctcaaaac ggagttaacg gctttcctcg
    37021 attacgaaaa gtacgatcgc attggtttta acacggggaa ttctcgtaac ggctcctatg
    37081 accgtacggt caagaccgag tacggggaac ttcatctcca gattccgcgc gaccgcaacg
    37141 gcgagttcaa gcaacagact gttcctgctt atagacggac gaatgatatc ttagaggaga
    37201 ccgtcattca cctcttccga aaaggtatta ccatgtcgga aatcgcagac ttgattgaga
    37261 aaatgtatgg gcatcactac acgccccaaa ccatgtccaa catgactaaa gtgctgactg
    37321 aagaagtaaa tgcatttaaa gttagaactc taaatgataa gtatgtcgct attttcatgg
    37381 atgctactta tattccttta aaacggcaaa ccgtctccaa agaagcaatc tatattgcca
    37441 ttggtatacg agaagacggc actaaagaag tactaagtta tgcgattgct ccgactgaat
    37501 cgacctacgt ttggaatgag ttgttacagg acatttactc cagaggggtt catgatgtct
    37561 tactgtttat taccgatggc ttaaaaggca tgaaagatac gattcaccag atttatccta
    37621 aagctaaata ccaacattgc tgtgttcacg tttcccgtaa tattgctcat aaagtacgtg
    37681 tcaaagatcg aaaagaaatc tgtgatgatt ttaaggctgt ttatcaagct agctcaaagg
    37741 aagaggcaaa taccttttta gggagtatga ttgagaagta gcaaaaaact tatcctaaag
    37801 tgacgcagtc actgataaaa aatcaagatt tattgacttt ttatgagttt ccgcctggta
    37861 tccgccgaag catttactca actaatttaa tcgaatcttt caagaaacaa atcaagaaat
    37921 acagccgcag aaaagagcag tttcaaaatg aagaatcact agagcgtttc ctagtatcca
    37981 tctttgatac atacaatcaa aaattcttaa atagaagcca taaaggcttc caacaagtga
    38041 cggatacatt agcttcaatg tttactgagt aacccattat tttgcagaag gacgagttat
    38101 ttacacaaaa ttattgacgc tccctccaaa ttacttcatc aaaacattga tataattttt
    38161 attatatcag tatttattct tgatacataa atgagaaaat aaatacttta aatctattga
    38221 ctacaagtag tcattaagtc ttcataagat gtacaatatg acattaaaaa aataaaagct
    38281 tacgaccatc cgttaaatct gacactaaat aatggactgc tttcttttgt attagcaggt
    38341 tacgttgact atgaatattc accagattat ttggagaaac ctcttcaaca cgagaacaat
    38401 gatattaatt ttagatttgt ctacgagtca aaaagtaaaa catggttagt tgatcaatta
    38461 agcacgataa acacaagctt ccatgaatta cctaaacctg aaaatgaagt tgagatggtc
    38521 attaaaatct tctaaaaaag aagcgttgaa ggggaaatat tcctttcaac gctctttttt
    38581 atatgcttag aaacataaat aaattgtata ctttcttttt agcccctatt acttttcacg
    38641 aaaaatatct ttttttcgac gctagcgttt ctctacttct aatactgtac acagtttttg
    38701 tattattgaa aaattactca ttatttagca ttaatccaca tcgttttatc aatcgacctt
    38761 catactaaac tactttaaag tcatcttcct tctcgttttt catt
//
LOCUS       DAZKKZ010000022        38179 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.022, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000022 DAZKKZ010000000
VERSION     DAZKKZ010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 38179)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38179)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38179
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.022"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(21..170)
                     /locus_tag="ACG8LA_001212"
     CDS             complement(21..170)
                     /locus_tag="ACG8LA_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0203519.1"
                     /translation="MKKKVIPYCPKPRNAFERGLFKYFEGKKGQDHKEENQKKKSKKR
                     SEYIF"
     gene            1138..1464
                     /locus_tag="ACG8LA_001213"
     CDS             1138..1464
                     /locus_tag="ACG8LA_001213"
                     /inference="COORDINATES: protein motif:HMM:NF013698.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFQ0203520.1"
                     /translation="MFKIFRKNCCGLDVHKTWIYACIGITDANGRTVYKQARFSSFTK
                     GLNELAEWLAKYNCKDVCLESSGKFWIPVFNILEKTCFVTLAHPKYTKPQKGNKTDRK
                     DAKMDL"
     gene            1472..2380
                     /locus_tag="ACG8LA_001214"
     CDS             1472..2380
                     /locus_tag="ACG8LA_001214"
                     /inference="COORDINATES: protein motif:HMM:NF033542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HFQ0203521.1"
                     /translation="MCDMIKPSFIPGLEIRQLRDLMRYRTKLTNMKTSEKNRALNCLT
                     VSNLKLDDVFSDVFGKSSTSIIQYLLEHPGESFDVRPFIHARCKTPVEEIQAAVEGAI
                     SVPQAIKLRQCLNHINEIEKHREEINLEIQALAEPFSPVLELLRTIPGLDTQPITAIA
                     ILSEIGPDMSVFPTSKHFISWAGCCPRNDRSARRTKSTRISRAGQSLKPLLVQIANAL
                     LRSKEHPEFKNRYRRIKANRGHKKAIIAICKMLLTAIWNVLSKVEPYSAKGYLEPKPA
                     KEEKVLTQSQALDLLRKRGYTIIDSA"
     gene            3006..3260
                     /locus_tag="ACG8LA_001215"
     CDS             3006..3260
                     /locus_tag="ACG8LA_001215"
                     /inference="COORDINATES: protein motif:HMM:NF013224.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC ligand binding domain-containing
                     protein"
                     /protein_id="HFQ0203522.1"
                     /translation="MIKSNQKSGFYTFIKAISSVLECDCIIGPYSMLIKMGFPSTESL
                     DSFINDLSKFGRTNTQIVFSTLVSLMVYQFWNVYHALLLK"
     gene            3802..3960
                     /locus_tag="ACG8LA_001216"
     CDS             3802..3960
                     /locus_tag="ACG8LA_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0203523.1"
                     /translation="MNKKQACEFLGIDNNTLDKWIRVYNFPVIKIDGVVRFDVEDIKD
                     FMNTFKKN"
     gene            4032..5258
                     /locus_tag="ACG8LA_001217"
     CDS             4032..5258
                     /locus_tag="ACG8LA_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFQ0203524.1"
                     /translation="MPTKLSNGKYKTNLRYPKKFREITGIASEKYQKVFPTRQLAIKA
                     EREMKKKIETVLREENANSLELKGKIKFKDFYESKWLPRYELGQTTRSNRAPSNVTIS
                     NTKDIFRLHILPMFGEYAMNYLNSNTEIISDELTKKSKEYANIKIIKGYVRSMFDIAE
                     ILCYIEFNRTTKIIQCITAPKKMALEEKRIREGNQALSSEELTDWIEAVNNDLNNHLL
                     TLHDYTLFMLTLYLGDRKSETYALQWKYIDFNKNTVRLKYALDKYQRKTHTKGWKDTV
                     IQAPEVVMTLLREWKSAQAEQLLKLKIIQTPDQYLFTYSKPSGEVNCPVHADYLNYRI
                     NAIKKRHPELAQLSPHKLRHTYATIAREGGANMNQISNALTHSDISTTKIYVNTPDVV
                     DKSVFEAFQKGLNKCD"
     gene            complement(5347..5739)
                     /gene="rpsI"
                     /locus_tag="ACG8LA_001218"
     CDS             complement(5347..5739)
                     /gene="rpsI"
                     /locus_tag="ACG8LA_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HFQ0203525.1"
                     /translation="MAQVQYIGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     REVINQPFAVTETKGAYDVFVNVNGGGYAGQSGAIRHGIARALLEVDPDFRLALKRAG
                     LLTRDARMVERKKPGLKKARKASQFSKR"
     gene            complement(5755..6183)
                     /gene="rplM"
                     /locus_tag="ACG8LA_001219"
     CDS             complement(5755..6183)
                     /gene="rplM"
                     /locus_tag="ACG8LA_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HFQ0203526.1"
                     /translation="MAKPGEVERKWYVVDATDVPLGRLSTVVASVLRGKNKPTFTPHL
                     DTGDFVIVINADKVKLTGKKATDKIYYRHSNYPGGLKSITAGELRAKNSRRLIETSVK
                     GMLPKNTLGRKQFTKLNVYGGAEHPHAAQQPEVLDITNLI"
     gene            complement(6717..7184)
                     /locus_tag="ACG8LA_001220"
     CDS             complement(6717..7184)
                     /locus_tag="ACG8LA_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HFQ0203527.1"
                     /translation="MKFQQTKEVLNQLVADLSQMSVVVHQTHWYMRGPGFLTLHPMMD
                     EFMDDLNAQLDEVSERLITLDGSPYSTLREFADNTKIPDEIGRWDRTIPERLETLVAG
                     YRYLADLYQKGIEVSGEEGDDPTQDIFIEFKTATEKRIWMIQAHLGKAPEIDA"
     gene            complement(7304..8842)
                     /locus_tag="ACG8LA_001221"
     CDS             complement(7304..8842)
                     /locus_tag="ACG8LA_001221"
                     /EC_number="2.7.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046316 - gluconokinase activity [Evidence
                     IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA];
                     GO_process: GO:0046177 - D-gluconate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gluconokinase"
                     /protein_id="HFQ0203528.1"
                     /translation="MNVSIGLDIGTTQTKAVAFTDEAQEAASAYFRYPLIQETQGMAE
                     QDQELIFQGVCTVIKEVIKQLPSDTIIQFVSFSSAMHGLILLDEEKTPLSRMITWADN
                     RAADEAEKLKYTVLGKEFYRQTGTPIHPMTPLNKIKWLQNSQPELFKKTAYFVGIKDY
                     IFYRLFGELISDYGTASGTGYFDIHEFQWAEEVLDYLNIRIEQLPQVFPSTYQVTGLP
                     SKTAAELGLPNDISFVLGGADGPLSNLGLGAFGDTIAALTVGTSGALRFITTQPQFHP
                     EMETFCYVLDQKHWVVGGATSNGAGIFDWAGHTFLQEVVQSAKEKGENPYDALLSAIA
                     FVPAGANGLIFHPYLLGERAPLWDADAFGSFIGLQRQHTEKEMMKAILEGICLNLYRI
                     LKGVCQENQLTEIRATGGFAQSPIFRQMMADVLGYPLVFPTVTEASALGAVILGWRSI
                     GKIQSISEAQELIELKEQVGVQETDHKKYQKIYPLFVSTQKHLAQTYQQFAQLREELA
                     DSEK"
     gene            8922..9608
                     /locus_tag="ACG8LA_001222"
     CDS             8922..9608
                     /locus_tag="ACG8LA_001222"
                     /EC_number="3.4.23.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="A24 family peptidase"
                     /protein_id="HFQ0203529.1"
                     /translation="MLLYFIIGCCIGSFLCLTAQRIPLGHSIIYPRSHCVKCCRSLSW
                     YELIPILSIIVQRFRCRYCRCRLPFYYLLAEALCGGLFAWFFTFSSARNFSTFIWMLS
                     ALLFSLMDLFYFMVHSHTLFCSWAILWIFWLQAGVFQWQSVLLTFIVGGVCLRYGQSY
                     LGAGDTLLMLSWSGGLSLEELLQILFLASLFGISVFSVYFICHKKKLEKLPFIPFLSS
                     ALLIVLHLRY"
     gene            complement(9809..10336)
                     /gene="msrA"
                     /locus_tag="ACG8LA_001223"
     CDS             complement(9809..10336)
                     /gene="msrA"
                     /locus_tag="ACG8LA_001223"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008113 - peptide-methionine (S)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_function: GO:0033744 -
                     L-methionine:thioredoxin-disulfide S-oxidoreductase
                     activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HFQ0203530.1"
                     /translation="MTKKAVFAGGCFWCMVKPFEEQPGIISVTSGYTGGHVPNPTYEQ
                     VTTGTTGHTEAVEIEYDPEVISYDQLVEIYWQQTDPTDALGQFADRGDSYRPVIYYND
                     EEERNIAERSKQALQDSGRFDKPIVTKIEPRSEFYPAEDYHQDYYKKNKLHYNLYREG
                     SGRAGFLRRHWGVKK"
     gene            complement(10420..11097)
                     /gene="pgmB"
                     /locus_tag="ACG8LA_001224"
     CDS             complement(10420..11097)
                     /gene="pgmB"
                     /locus_tag="ACG8LA_001224"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008801 - beta-phosphoglucomutase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HFQ0203531.1"
                     /translation="MKIKAALFDLDGVLVDTARYHYEAWLVLANQLSIPFTEKENEQL
                     KGISRTESLERLLSFGKMEQKFSEKEKSAFAEQKNNLYLQAIQKMDETSVLPGAIAVL
                     EYLKKTNIKIGLGSASKNARLILEKTNLTSYFDVLIDGTQVSKAKPDPEVFLKGAQQL
                     NVPPNACLVIEDSEAGCQAALAGNMHVLGIGENINLPSAEYVIPDLTVFDQVRSFWHL
                     SEAVSRI"
     gene            complement(11094..12222)
                     /locus_tag="ACG8LA_001225"
                     /pseudo
     CDS             complement(11094..12222)
                     /locus_tag="ACG8LA_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302353.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
     gene            complement(12222..14405)
                     /locus_tag="ACG8LA_001226"
     CDS             complement(12222..14405)
                     /locus_tag="ACG8LA_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 65 protein"
                     /protein_id="HFQ0203532.1"
                     /translation="MKVEEKQFDLEYINKYASQMTIGNGFFGIRGSQEEDYRNQVRGM
                     FAAGVYNRPLGAESAELVNLPDVIRWEIKIDGEHFSLETMKVLAYERALDLEMGELKR
                     YALIETAQGKKVEVITCRVADQNNLHQAALKVVIKPLTEDCQVDVKTGIDGQQTNFGT
                     QQLVEKELRVFGDDLISASYQTTESKIDIGIAAKFNKAGVFQAKNRRITASFSEKIRK
                     NTSFTLEKIIVLSTSLQQTDPFKKSIAQAQKSVSYTEILEQSMSYWTDFWHQHRITIQ
                     GDSSFDQLAMDFAAYHLQIMTPRNDPSVSVGAKGLTGEGYKGHVFWDTEIFILPFFLY
                     QFPEVAKNLLLYRYDRLEGARQKARDYHYQGALFPWESAHTGQEETPKFAALNIKTGT
                     RQEVASAAAEHHISADLAYAVQEYVQATEDQSFLETKGKTLIHETAAFWLSRAVKVDD
                     HLEIHRVIGPDEYTEYIDNNAYTNYLAHYNVALAVKYQAGDPLFLKECQNFLDKLYLP
                     VPNKEQLIPQDDTYLSKPVIDLTTYKERPGSQSILLDYARSEVNELQVSKQADLVMLL
                     YLLPEYFSQPIVSKNLHYYENKTIHDSSLSKAIHAIEACRIQEMEWAYHLFQEACLID
                     LGPDPHSSDDGIHAASLGALWLAVIFGFSGITVTNGTLSISPRLPSAWEKISFPFIWK
                     NHRLLFVLTKKQIVIKKETKETLPIFVNGDQYQLEKELILERRGK"
     gene            complement(14402..15427)
                     /locus_tag="ACG8LA_001227"
     CDS             complement(14402..15427)
                     /locus_tag="ACG8LA_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFQ0203533.1"
                     /translation="MKKVAIIGAGQVAEKVHAAYYQKRSDVLELAAVVDPVSQRAEDF
                     CRRTGFSHAYTSVTQMLNEISPDIVSVCTANRFHFEHVLAALEANASVMCEKPPAMTA
                     DQARKMAETADKNGQILAYGFQHRFSDEATMIKNHLDVLGDIYYVEANALRRSGVPGW
                     GTFIDKELQGGGPLIDYGIHMLDTAMYITGFPKVKSVRAYSFQKIGTKKNSGKFGKWD
                     PSKFTVEDAIFGTLELENGKIIQLNTSFALNIREDKLNVAFCGDQAGANLYPGELFED
                     VDGKLVSLQKTTPVNDPHELSMAHFVNRALGDQTQMIADGWQGYVIQNLVENLYRSAE
                     TGEVITL"
     gene            complement(15472..16299)
                     /locus_tag="ACG8LA_001228"
     CDS             complement(15472..16299)
                     /locus_tag="ACG8LA_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase family
                     protein"
                     /protein_id="HFQ0203534.1"
                     /translation="MKFGTQDQAFFPRDILEKFRFIKDCGFEEYEIDGKLLIENIDTV
                     KQAIKETGIPVVTACNGYDGWIGDFIEERRLNGVRQIAEILRALSEVGGKGIVIPAAW
                     GMFTYRLPPMVSPRSKEGDYKAVSESLRYLDKVAEETGTVIYLEPLNRYQDHMINLLA
                     DARHYIDSNQLKHVQIIADFYHMNIEEDDISKALTTQKEYVGHIHLADNHRYQPGSGA
                     IDFTRHFQTLLQNEYEGYMVYECRLRGENEVKIYQESLQYLKNCLETARHLNDLEKE"
     gene            complement(16296..17363)
                     /locus_tag="ACG8LA_001229"
     CDS             complement(16296..17363)
                     /locus_tag="ACG8LA_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase"
                     /protein_id="HFQ0203535.1"
                     /translation="MKKLVALEPRIAGFKDYEDREIEKNEVRIRVIFATPKPGTEIVD
                     FRGLSPFIDEEFSEEWRLFLPREEGSQRGVVFGEFQLGNMIVGTIEETGSLVTEYQKG
                     ELVCTYGPIRETLITNGVDNYKLRKLDRLDQWKNAVCYDPAQFALGGIREAHVRAGDA
                     VAIFGLGAIGQIAIQLAKKAGATTIVGIDPIAQRRELAEKYGADYTLDPMKADVGFRL
                     KELTDKRGVDSVIETSGSAAALQASLRGIGYGGIISYVAFAKPFPAGFNLGREAHFNN
                     AKIVFARASSEPNPDYPRWNRKRIEDTCWELLMNGYLDCEEIIDPVVPFAESAEAYMR
                     YVDQHPEESIKMGVQVRGGEQ"
     gene            complement(17389..18225)
                     /locus_tag="ACG8LA_001230"
     CDS             complement(17389..18225)
                     /locus_tag="ACG8LA_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFQ0203536.1"
                     /translation="MKNKKSRKILFYATILLLLAVNLFPFLIMLMTSFKDSQEAIATT
                     QTIFPKEWTFEHYQDIFNAEIFPFIMYFKNSLVISLIASVTAVVIGISGAYALSKLRF
                     KARSKINASFYTVYMFSGILIVVPLFKIISGLGLYDTNTALIITMVVQTLPTAIFMLK
                     SYFDTIPTDIEEAAMIDGLSRIQIIIRIIIPLAISGIISVFVYCFMVSWNDYLFASIF
                     LSTSEKFTLPIGLNTLFSTPDYIWGRMMAASLVTALPVIIMYALSERFIKGDLVEGGV
                     KG"
     gene            complement(18222..19091)
                     /locus_tag="ACG8LA_001231"
     CDS             complement(18222..19091)
                     /locus_tag="ACG8LA_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFQ0203537.1"
                     /translation="MNRPRKHSDLKLAMGLLAPSMLLLAVLVLIPMLSNIQISFFDMP
                     LNPNSDAVFIGLSNYLEILSDSEFYRSLGLTVAYTFLVVAGSTALGLAVAILLNRKFR
                     FRKTVRSLILLSYVTPSISLIFAWKYMFNNSYGIVNDLLVDRLQLFNEAPLWFDQPVA
                     SFFMVVLFAIWRYYPYAFISFLAILQTVDKTLYEAAEMDGANAWQKFKIVTLPAIKPV
                     LATVIVLRSIWMFYMFTDVYLLTNKVNILGVYLYQTAFAFNDLGKAAAISILLFIIIA
                     AVVLLSRKKVDLK"
     gene            complement(19161..20444)
                     /locus_tag="ACG8LA_001232"
     CDS             complement(19161..20444)
                     /locus_tag="ACG8LA_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFQ0203538.1"
                     /translation="MKKIIVTTCLLATGFLLTACGESQSSNESQQTTIQFMHSSVEQE
                     RLSVINELVADFEKENPDIKIKQVPVEESAFNTKIVTLARSGKLPEVMEVSQDFAKVM
                     DKDELIDQTAVQNVIEEAGEDNYYDGAKNLVRSEDGKSYIAAPISGWVQGIWYDKEKL
                     SEAGFSEPENWDDILKIAQHFTDKENKQYGIAMPTAEGTMSEQAFSQFALSNGANVLD
                     DEGEVTIDTEKMREALSFYQNLSQYTMPGSNDVTEIKDAFMNGTAPMAIYSTYILPSV
                     YEAGNSENIGFAIPTQKDQAVYGTVSGLTISSGLDEKQKEAAEAFTAFLSQPKNMEKW
                     VLMSPGGAQPVNKQVVELDGYKENEVIKSFGELPSEIASAFDEVQVFGLVGEKNFTKM
                     GDITSSGVIGKAVNQVTVGNEDVDQALADAQKNTK"
     gene            complement(20458..22143)
                     /locus_tag="ACG8LA_001233"
     CDS             complement(20458..22143)
                     /locus_tag="ACG8LA_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase family glycosyl hydrolase"
                     /protein_id="HFQ0203539.1"
                     /translation="MYTKLLQAIYRDSDLSEKTASMIEQKVSVYQQKKGQAGKLHWDE
                     EDIFLITYGDQFFEEQQPTLRTFKKFYQKYLADTFRVVHFLPFFPYTSDDGFSVVNYQ
                     AINDRLGTWEDIEEMRSETRLMFDFVCNHMSAESTWFQEYLNLNDTYKDFFIDLPLDT
                     DTSSVTRPRTSPLLTTFIDKNGKEKHVWTTFSEDQVDLNFKNPEVLLKMIDILLFYLE
                     KGASFIRLDAVGFLWKELGTSCIHLPETHKIIQLFRAIADEAAPGTVLITETNVPHKD
                     NISYFGNGENEAQMVYQFSLPPLTLQAIRSGNTSKLKEWLKTIDFASKKTTFFNFLAS
                     HDGIGLNPVRGILPEKTILELVEQLKKEGARVNYKKNPDGTTSPYEINATYLDALSSP
                     TDTTEWRSKRFLAAHSFLVTLPGVPAIYIQSVLGSRNDYKGVEKTGENRKINRQKFLL
                     ADIEKELQTDPLRTAVYGELTQMLSIRKKEKAFHPNSLIYLLDSADSFISFIREAKEE
                     KVLVIHNFSNQSAGYLLPKGDYLDLFSGQIIHCSQERKLIFQPYEYMWLKIIK"
     gene            22418..23443
                     /locus_tag="ACG8LA_001234"
     CDS             22418..23443
                     /locus_tag="ACG8LA_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFQ0203540.1"
                     /translation="MKPTIYDIAKKANVSKSTVSRVLNNQPNISDKAKASVLQAIKEL
                     NYEPSKIARGLSGNGFDAILALSHRTSHTTYGNPFFSDVIQSISAVSEQNNFDLILQT
                     AKTPEEELEKCAKKIQEKMIRGIIILSSTMDETLLFELDQYNIPIVVIGKVGNDYTNI
                     YSVDTDNFQDSYDLVETLIKNGHRHIGCLHAPTEVYVSNDRLNGYRQCLFDHHLDIRN
                     EWIIDGGFRLEDSMAAMNDLMKLRERPTAIFSTDALKSLSIYKVAEQSGKQIPDDLSI
                     AGFSDPLLSSLFSPQLTRIDIPTNQLGIKATELLFQLIHHQYPEEKRIILSTEITLTD
                     SIQQQEM"
     gene            complement(24038..27691)
                     /gene="rpoC"
                     /locus_tag="ACG8LA_001235"
     CDS             complement(24038..27691)
                     /gene="rpoC"
                     /locus_tag="ACG8LA_001235"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HFQ0203541.1"
                     /translation="MIDVNKFESMQIGLASPEKIRSWSYGEVKKPETINYRTLKPERE
                     GLFCERIFGPTKDWECACGKYKRIRYKGIVCDRCGVEVTRSKVRRERMGHIELAAPVS
                     HIWYFKGIPSRMGLVLDMSPRALEEIIYFASYVVIEPGNTNLEKKQLLTEREYREKRE
                     QYGQEFQAAMGAEAIKQLLDNVDLDAEAAELKEELKSAQGQKRTRAIRRLDILEAFRA
                     SGNQPSWMVMDVIPVIPPDLRPMVQLEGGRFATSDLNDLYRRVINRNNRLKRLLDLNA
                     PGIIVQNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSHMLKGKQGRFRQNLLGK
                     RVDYSGRSVIVVGPFLKMYQCGLPKEMAIELFKPFVMRELVQRELASNIKNAKRKIER
                     QEDEVWDVLEDVIKEHPVLLNRAPTLHRLGIQAFEPVLVQGRAIRLHPLVCEAYNADF
                     DGDQMAVHVPLNEEAQAEARMLMLAAQNILNPKDGKPVVTPSQDMVLGNYYLTMEEEG
                     REGEGMVFRDQNEAVIAWRNGYVHLHSRIGVNPNSLGEKPFTEWQKERTMITTVGKII
                     FNEIMPPEFPYLNEPTDFNLTVQTPDKYFVEAGTDIPAHIKEQELVLPFKKKNLGNII
                     AEVFKRFKVKETSKMLDRMKDLGYKHSTHAGITVGIADISVLNEKQEIIENAHKQVET
                     ITKQFRRGLITDDERYERVIAVWNAAKDSIQQKLMEGLEAKNPIFMMSDSGARGNISN
                     FTQLAGMRGLMAAPNGRIMELPIISNFREGLSVLEMFISTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREEDCGTDRGLEIQAIREGNEIIESLEDRLVGRYTRKEVRHPE
                     TNELIIAGNQLISEDIAKQIVDAGVETVTIRSVFTCNTKHGVCKHCYGRNLATGSDVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVAGDDITQGLPRVQEIFEARNPKGQAVIT
                     EVTGDVIDISEDPATRTKEVTIKGKTDTRTYTVPYTARMKVAEGDMIHRGAPLTEGSI
                     DPKQLLQVRDVLSVENYLLREVQRVYRMQGVEIGDKHIEVMVRQMLRKVRVMDPGDTD
                     ILPGTLLDIADFKDQNYNTLVSGGVPATSRPVLLGITKASLETNSFLSAASFQETTRV
                     LTDAAIRGKKDPLLGLKENVIIGKIIPAGTGMQRYRDMEPKEVGVASENVYSISDIEA
                     QMAAEDAMNNQTK"
     gene            complement(27770..31387)
                     /gene="rpoB"
                     /locus_tag="ACG8LA_001236"
     CDS             complement(27770..31387)
                     /gene="rpoB"
                     /locus_tag="ACG8LA_001236"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HFQ0203542.1"
                     /translation="MAGHVVKYGKHRERRSFARISEVLELPNLIEIQTDSYQWFLDEG
                     LREMFEDILPIDDFNGNLSLEFVDYELKEPKYTVAEARAHDANYSAPLHVTLRLTNRE
                     TGEIKAQEVFFGDFPLMTEQGTFIINGAERVIVSQLVRSPGVYFHGKVDKNGKEGFGS
                     TVIPNRGAWLEMETDAKDISYVRIDRTRKIPLTVLVRALGFGSDDTIFEIFGDSETLR
                     NTVEKDLHKNASDSRTEEGLKDVYERLRPGEPKTADSSRNLLNARFFDPKRYDLANVG
                     RYKVNKKLDLKTRLLNLTLAETLVDPETGEIIVEKGTVLTHQVMETLAPFIDNGLNSV
                     TYYPSEDGVVTDPMTVQVIKVFSPRDPEREVNVIGNGYPEAAVKTVRPADIIASMSYF
                     LNLMEGIGNVDDIDHLGNRRIRSVGELLQNQFRIGLARMERVVRERMSIQDTETLTPQ
                     QLINIRPVVASIKEFFGSSQLSQFMDQTNPLGELTHKRRLFALGPGGLTRDRAGYEVR
                     DVHYSHYGRMCPIETPEGPNIGLINSLSSYAKVNKFGFIETPYRRVDRETGRVTDQID
                     YLTADIEDHYIVAQANSPLNEDGTFAQDVVMARAQSENLEVSIDKVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPWVGTGMEYKSAHDSGAALLCKH
                     DGVVEYVDASEIRVRRDNGALDKYDVTKFRRSNSGTSYNQRPIVHLGEKVEKGDTLAD
                     GPSMEQGEMALGQNVLVGFMTWEGYNYEDAIIMSRRLVKDDVYTSIHIEEYESEARDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVQDGDLLVGKVTPKGVTELSAEERL
                     LHAIFGEKAREVRDTSLRVPHGGGGIVHDVKIFTREAGDELSPGVNMLVRVYIVQKRK
                     IHEGDKMAGRHGNKGVVSRIMPEEDMPFLPDGTPIDIMLNPLGVPSRMNIGQVLELHL
                     GMAARQLGIHVATPVFDGASDEDVWETVREAGMASDAKTVLYDGRTGEPFDGRVSVGV
                     MYMIKLAHMVDDKLHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTL
                     QEILTYKSDDVVGRVKTYEAIVKGEPIPKPGVPESFRVLVKELQSLGLDMRVLDIEET
                     EIELRDMDDEDDDLITVDALTKFAEQQTAKELEKKAAEQVEDEKDDVIQNFETAEDNL
                     D"
     gene            32115..33083
                     /locus_tag="ACG8LA_001237"
     CDS             32115..33083
                     /locus_tag="ACG8LA_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFQ0203543.1"
                     /translation="MKKNIIIGLGAALLLALGGCAQKDNSAEASDGQKTIGVLQLVQH
                     NSLDAAYKGFKEGLAEEGYKEGDNLTIDYQNAQNNQDNLKSMSEKLVKEDPDLLLGIA
                     TPAAQSLLNETTTIPMTVTAVTDLEQAHLVTSNEKPGGNVTGTTDMVPIEKQIGLLLN
                     IVPDAKTIGIMYNNGEANSKIQADLAEKELKKAGVKVKVLTANSTNDVQQVTKSLAKD
                     VDGIYIPTDNTFASAASVVGEVAKETKTPVVAGAVDQVKDGGLATVGIDYESLGKQTG
                     IMAAKILDGKNPSELPVETANDLELYVNKDMAKALGINPDSIKEAE"
     gene            33101..34006
                     /locus_tag="ACG8LA_001238"
     CDS             33101..34006
                     /locus_tag="ACG8LA_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFQ0203544.1"
                     /translation="MTNLLSLFLSSASQGVLWALLAIGVYVTFRILDIADLTAEGSFP
                     LGAGIAAVSITNGYHPLTACLLGFLGSAAAGLVSGLLHTKLKIPALLAGIITMTGLYS
                     VTSRVMGAPNISLLGQPTIFHWVESFGITKDNAVLIVGLLFALIVVCLLVLFLRTETG
                     LAIRATGDNLAMSEANGINTDNMKIIGYMISNGCIALSGSLLAQNNGFADLNSGIGTI
                     VIGLASIIIAEVLLRNQPLFLRLLTVVLGAVIYRFILALVFELNVEPSDSKLASAFVL
                     VICLSFPQIQQKFHLPQKKKGGSVK"
     gene            34003..34809
                     /locus_tag="ACG8LA_001239"
     CDS             34003..34809
                     /locus_tag="ACG8LA_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0203545.1"
                     /translation="MNDVLTLENLHHTFEKGTINENHVLKGINLSLDPGDFVTIIGGN
                     GAGKSTLLNSIAGTFSVDQGQILLNGKNITKKSVVERSKSISRVFQDPKLGTAVRLTV
                     EENLALAMKRGKKRGFFRGVKPQDRTFFKDQLVRLNLGLENRLSSEIGLLSGGQRQAI
                     TLLMATLQRPELILLDEHTAALDPATSKTVMELTEKLITEQNLTAFMVTHDMEDAIRY
                     GSRLIMLHQGRIVVDIQQEEKQQLTVPQLLALFKQNSGTALKDDQVLLSS"
     gene            34966..35934
                     /locus_tag="ACG8LA_001240"
     CDS             34966..35934
                     /locus_tag="ACG8LA_001240"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004077 - biotin-[acetyl-CoA-carboxylase]
                     ligase activity [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="biotin--[acetyl-CoA-carboxylase] ligase"
                     /protein_id="HFQ0203546.1"
                     /translation="MTTKDKVLQLLKKTPDFLSGEKLAQQLEVSRTSIWKAIKELEKA
                     GYRFEHGPTGYRYLPSDVLDAKEIQQELRSFIPDLKVQTMMTSESTMKDAKLAAAQGD
                     SVSKLFVADTQEQARGRFGRPFFAEPGRGIYMSLLLHPDKRFDELPQYTIIAASACVK
                     AIESVTGRSASIKWVNDIYMDGKKVCGILSEAVSDMESGRISHIIIGIGLNFSVPQNH
                     FPADLQEKAISVFPDGQASVTRNQLISKIWQELFTYLSHPEKALDFYKEKSFVLGKTV
                     SFNQKGTTYVGLAKEIGDHGELIVQTNEQKMSLSSGEISLTSIRTQ"
     gene            complement(36251..36775)
                     /locus_tag="ACG8LA_001241"
     CDS             complement(36251..36775)
                     /locus_tag="ACG8LA_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF664 domain-containing protein"
                     /protein_id="HFQ0203547.1"
                     /translation="MDYLDMLCESVDRAYDRFERLFEGVSIEEANRFPVEDRAPQIKS
                     MTWLAWHTARELDFQIADLAGTSPIWHSQDWESRFPMTIADNEQDWKHSLEQAKQIQA
                     NQIEDLLGYLRGAADFAISYLRRLEPSELDEVIDENWTPPVTRGMRLVSIIDDAAMHS
                     GQVIYARRLLGLRD"
     gene            37062..>38179
                     /gene="scm"
                     /locus_tag="ACG8LA_001242"
     CDS             37062..>38179
                     /gene="scm"
                     /locus_tag="ACG8LA_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HFQ0203548.1"
                     /translation="MKKRASLLVLVALLFNIFSYGVAVSAETYIPKDPGNIYNDLTGN
                     YGLLGIASQFHVFAKNKTTVNAHTDGNIATHELDAKNNFGTELHEGLLNQEINYIQKT
                     DSFANSSGIPTGSTRMNKFVVGSNVDVALQDGHPTVNGSRLDHLTPDDFYKDRAGHEY
                     IDFEQEFAKLNVAANDLATITPAKTYTAADFPDMNNRTIDLTDLSDTGFLLVNIDAEV
                     LTMNTPLQIINPNDQVVVFNVINSSSALNVQSPIKYNDRSNHETEDFSDANISWNFGN
                     EMTDLTISAPFQGTILAPNATIRITQNQDGTIIGTNVILDAATNRWDPNEIFISDNGT
                     DTTDTSDSTDTSTTSDSSDSSTSSDSTDTTSTTSDSTDT"
BASE COUNT        11002 a         8056 c         7100 g        12021 t
ORIGIN      
        1 acgttccagt tttattcttt ctaaaaaata tactcacttc ttttcttaga cttctttttt
       61 tgattctcct ctttatggtc ttgtcctttt ttgccttcaa aatatttaaa taaacccctt
      121 tcaaaagcat ttctaggttt tggacaataa ggaatgactt ttttcttcat ataaatacct
      181 catttaacta tttgatatca tcacattatc aaaaaaaata ggttttttat taaaactatc
      241 ttgacctttc gggagatttc actgtgattt atttttattc ccatactttt ttcgttggtc
      301 actttcgtat acctaatcta agcgatcatc ggcgacggtg cttttacaac gaatggcagg
      361 acaaaacaag gggcggaaaa acttttttgc ctatttcata aaaaactttt tcctacagca
      421 atcccttgtt ttgtcctacc acacgttgtg aacccaaagc acgccgacga acgcttagct
      481 atacgaaaat gacctccaaa aacaaaaaag tgaggtgaat agaaacaaaa agaaattgaa
      541 atctcccaaa atgtcgtccg cctcggagac aacttgctgc tgaaaatggt tggttaattc
      601 atttaagtat taaataagat aaatcatcaa attaatcgga aaaatagcat gattggcctt
      661 atcaaaaata aactgtaaaa acttatattt ctatgagtgg tggaacaatg ctaataccaa
      721 attaatttat cgattaccca cctgcacaaa ccaaagatag cattattagg aaacgaatca
      781 atcagcgaat ccagcattat aatgaggata ctaaaaataa agttttcata attataaatc
      841 cgccttccta cgaaaggcac caatgaggtg atgaaaacct tagagcgctt tctttctttt
      901 tttattccgt gttacccttt ccttgcaggt ccctggtaca ctacagaacc cgaggaggtg
      961 agtggcgggg ctgtatagcg gcaaccccgc ataattatat ggtgtcggtc atccgttaag
     1021 gcatcaatga atggcgcaaa cccgtagccc gtaaacttat ctcttccgaa gttgactcga
     1081 tttcgccgga tgaccagtcc ctaccaaacc tgtactattt ttttacagga ggttgctatg
     1141 ttcaaaatct ttcgtaaaaa ttgttgtggc ttggatgtcc acaaaacgtg gatctatgcg
     1201 tgtatcggaa tcacagatgc gaatggtcgt acagtgtata agcaagctcg cttctcttcc
     1261 tttacaaaag gtctcaatga attagctgaa tggcttgcta aatacaactg taaggatgtg
     1321 tgtttggaat cttccggtaa attttggatt cctgttttta atattcttga aaaaacttgt
     1381 tttgtcacac tggctcatcc gaagtacacc aaaccccaga aaggaaataa aacagatcgc
     1441 aaagatgcaa aaatggattt gtgatctctt tatgtgcgac atgatcaaac ccagttttat
     1501 tcctggtctt gaaatccgcc agcttcgtga tctaatgcgt tatcggacga aactgaccaa
     1561 catgaaaaca agtgaaaaga atcgtgcttt aaactgctta accgtttcta atctgaaact
     1621 agatgatgtt tttagtgatg tgttcggaaa atcatccact tctatcatcc aatacttgtt
     1681 agaacatccc ggtgaatcat ttgatgttcg accatttatc catgcccgtt gtaaaactcc
     1741 cgttgaagaa atccaagcgg cagttgaggg ggcgatttct gtacctcaag cgattaagct
     1801 tcgccaatgc ctcaaccata ttaacgagat tgagaagcat cgagaagaga tcaatctaga
     1861 gattcaagct cttgcagaac ccttctcccc tgttttggaa ctacttcgta ccataccggg
     1921 cttagacact cagccaataa cagcgattgc gattctttca gaaataggac cggatatgtc
     1981 cgtgtttcca acttcgaaac actttatttc ttgggctgga tgctgtccaa gaaacgatcg
     2041 cagtgcccga cgaacaaaat caacacgtat ctctcgtgca gggcagtcgt tgaaaccgct
     2101 acttgtacag attgccaatg ctcttctcag atccaaagaa catccagaat ttaaaaatcg
     2161 ctatcgtaga atcaaagcga atcgtggaca caagaaagct atcattgcta tttgtaagat
     2221 gctcctgacc gctatctgga atgtcttatc aaaggtggaa ccctattctg ctaaaggata
     2281 tctggagcca aaacctgcga aagaagagaa agttctgacg caatcccaag ctctggacct
     2341 tttaagaaaa cgcggatata ccattataga tagtgcttaa accaaagtta cgttgattct
     2401 tcctaaatag actcgttgtc ttccatttca aaaattttga aaacggtagg cttatttagt
     2461 gtaccgttct tcaggtatct tcaaatagat ttattttcaa acttatttcc tttcttcttt
     2521 tactctccta tagcttagca tttaagtggg cactcgtgtc accttgctag atagctatga
     2581 atgccgtaat aagcctccta gtatataggc agactgccaa ttataactga ttcaatccac
     2641 attatgataa aatccacctt ttcgtttcat atgtgttgaa atatcacata tgtcaaaagt
     2701 gcacgagtct tttcattcag tgctttgtaa atactcaaaa ttattccttt tcactttaaa
     2761 aaaaagataa ttagtacaaa atcagaaatg aggaaagtat taggatggac tagaaaggag
     2821 ttgttgaatt tgttgcaaca gattggtcat ttatcaatta aaaattaggt gaagttttat
     2881 tcatcactgc agctgctgtt tcccagagaa taaaacgtct agaagaaact ggtcagttac
     2941 tgtattatca agcagcaatt gactacgaac aagcttgatt actaaccaaa gcgtttatcc
     3001 acctgttgat taaatcaaat caaaaatcag gtttttatac gttcataaaa gcaatctcca
     3061 gtgtactcga atgtgactgt atcataggtc cttattcgat gttaatcaaa atggggtttc
     3121 cttctaccga atcattggac agttttatca atgatttatc aaagtttgga cgaaccaaca
     3181 cccaaatcgt tttctcgact cttgtttcct taatggttta tcagttctgg aatgtttatc
     3241 atgcgctttt attaaaatag aaaagagctt ttttcatgcg acaaagcagt gatcatttat
     3301 tggcacatgc aatctttgtg gatccatttt ttgaaaatac gatatttagt tttgacccaa
     3361 aaatctttaa atacgtattt gataatttat cttaacaacc agataatttt attcagcacc
     3421 gtattatcta tattgaattc tcggaatcaa gataaatttt tttccgtttt tgtttctttt
     3481 ttaatcttct tcttgttatt aatagtgatt aggatgatat tcctatattg atctttgata
     3541 attagatata atttttgaat aacgttccct gctattcgag ctagaaatac aagtacgcca
     3601 tgacctagtt agcgacaact acttagagat ttcttttgtt ctgggacaac aaaatgccat
     3661 gacaatagca gtaaataatg atacttccgt aaggctcgcc gtaaactggg gagaggtgaa
     3721 attcctatgt gcttacccaa agcggttcaa aaattttaaa ctattatttt aggagatgat
     3781 tttataaaat cgaaagccta cttgaataaa aaacaagcct gtgaatttct aggaattgat
     3841 aataatactt tagataagtg gattcgtgta tataattttc cagtaataaa aattgatggc
     3901 gtagttcgct ttgacgtaga ggatatcaaa gatttcatga atacattcaa aaaaaattga
     3961 aattttcttc tcgtcacata tactataaat agcgaaatgt actgccttac tttttaaagg
     4021 agtgaggaag tttgcctaca aagctttcaa atgggaaata taaaactaat ctgaggtatc
     4081 caaaaaaatt cagagaaatc actggaattg catcagagaa gtatcaaaaa gtatttccaa
     4141 ctaggcaatt agctattaag gccgaaaggg aaatgaaaaa gaagattgaa acagttttaa
     4201 gagaggagaa tgcaaactca ctagaattga aaggaaaaat aaaatttaaa gatttttatg
     4261 aatcaaaatg gcttcctaga tatgaactag gtcaaactac taggtcaaac agggctccaa
     4321 gtaatgtaac aattagtaat actaaggata tattccgatt gcacatcctt ccaatgtttg
     4381 gtgaatatgc aatgaattat ctgaattcaa atactgagat aatatcagat gaattaacaa
     4441 agaaatcgaa agaatacgca aatataaaaa ttatcaaagg ctatgttcgc tctatgtttg
     4501 atattgccga aatactatgt tatatcgaat tcaaccgaac taccaaaatt attcaatgta
     4561 ttaccgcgcc taagaaaatg gctttagaag aaaaaaggat aagggaaggg aatcaagcat
     4621 tatcatcaga agagctgact gattggatag aagcagtaaa caatgactta aataatcact
     4681 tgcttacact tcacgattac acacttttca tgcttacctt atatctaggt gatagaaaaa
     4741 gtgagactta tgctctgcaa tggaaatata ttgattttaa taaaaatacg gttcgtctca
     4801 aatatgcttt agataaatat caaagaaaga cacatacaaa aggttggaaa gacaccgtta
     4861 ttcaggcacc agaagttgtg atgacattat taagagaatg gaaatcagct caggctgaac
     4921 aattgttgaa actaaaaatt atacaaacac ctgaccagta cctctttacc tattccaaac
     4981 cttctggaga agtaaattgt cctgttcacg ctgactactt aaactatcga atcaatgcaa
     5041 taaaaaaaag gcatcctgaa ttggctcaat tatctccaca caaacttcgt catacctatg
     5101 caactatagc tagggaaggt ggagcaaata tgaatcaaat ctctaatgct ttaacgcact
     5161 cggatatttc tactacaaaa atatacgtga acacacctga cgtagttgat aaatctgttt
     5221 ttgaagcatt tcaaaaagga ttgaataagt gtgattaaca tgtgttctca aatgtgttct
     5281 tattataaaa aaagacactt tccaaataat tgaaaagtgt cctgaaatat tgatataaaa
     5341 agaatattaa cgttttgaga attgtgaagc tttacgagct tttttaagac ctggtttttt
     5401 acgttcgacc atacgtgcgt cacgagtaag taagccagca cgtttaagag ctaaacggaa
     5461 gtcaggatca acttctagca atgcacgagc gataccatga cggatagctc ctgattgtcc
     5521 agcgtatcct ccgccgttta cgttaacaaa tacgtcatat gcgccttttg tttcagtaac
     5581 agcgaaaggt tgattgatta cttcacgcaa gtcagcatgt ggaatgtatt cttcaacatc
     5641 ttttttattt acagtaattt tgccagttcc tggtactaga cgtacgcgag caactgcgtt
     5701 tttacgacgg cctgtgccga tatattgaac ttgtgccaat gaaattccct cctattagat
     5761 taagtttgtg atgtctaaaa cttctggttg ttgtgctgca tgtggatgtt ctgctccacc
     5821 gtatacgttc aattttgtaa attgtttgcg gcctaaagtg tttttaggaa gcataccttt
     5881 tacagaagtt tcgatcaaac gacgagaatt tttagcacgc aattcgccag cagtgattga
     5941 tttcaatcct cctgggtagt tgctgtgacg gtaataaatt ttgtcagtcg cttttttacc
     6001 tgttaatttc actttgtctg cattgatgac gatgacgaaa tcgccagtat ccaaatgagg
     6061 tgtgaaagtt ggtttatttt taccacgtag tacagatgca acaactgttg aaagacgtcc
     6121 caatggaaca tcagttgcgt ctactacata ccatttacgt tctacttcgc ctggtttggc
     6181 catatatgtt gtacgcacgt tattttcctc caatttaagt tctgatgttt gacatacact
     6241 tcgagtttcc ggggctcttt gtggggcaaa caataccatt taacatatta cccgctaatc
     6301 tagtcaatgt caacgttttt ctgcttgatt gaaaaattta tatgaaactt tacttctttt
     6361 ctttctttta tataaaaggg tcgtttcctg tcaaaatgaa aaacaaaaag aggctgtgac
     6421 aaaagtcttg tcacaacccc ttattttgaa taaacggtgt tctcctgcca actcctcggt
     6481 cacaagtcac aatatccata aaacataaga agctgttttt taaaattgtt tcttgtgact
     6541 cggagctgaa cggcaggctt acaacctctt ggtaaacggt gttcaatcag ctgaccctcg
     6601 gtattagctc aaaaaacggc aaaatatgag gaactatttt gacgtttgtt tctctaatac
     6661 tcaggtcaaa acgctgattt cacaacctct ttttcggtca agttcaacaa cagtttttac
     6721 gcgtcgatct ctggcgcttt gcccaaatga gcttggatca tccagatacg tttttctgtg
     6781 gctgttttga attcgataaa gatatcttgt gttggatcgt cgccttcttc tccagaaact
     6841 tcgattcctt tttggtaaag atctgctaga taacgatagc ctgcaacaag tgtttccaaa
     6901 cgttctggaa tagtacgatc ccagcggcca atttcatcag ggatttttgt gttatctgca
     6961 aattcacgca atgtagaata aggtgaaccg tctaatgtga tcaagcgttc ggatacttca
     7021 tctaactgag cgttcaaatc atccatgaac tcatccatca ttgggtgcaa tgtaaggaaa
     7081 cctggtcctc tcatgtacca atgtgtttgg tgaacaacaa cagacatttg gcttagatct
     7141 gcaactaatt gatttaatac ttctttggtt tgttggaatt tcatctttct tgcctcctaa
     7201 cattttctta cacttaaaat aatagtagac tttcaatgaa aagtacaaca aaatcattta
     7261 cctgagaacg attttcagtt cgctttttta tccgtaaagc caatcatttt tcagaatcag
     7321 ctaattcttc tcgcagttga gcaaattgct gataagtctg tgctaaatgc ttttgtgtcg
     7381 aaacaaataa tggatagatt ttctgatatt ttttatgatc agtttcttgt actccaactt
     7441 gctctttcaa ttctatcaat tcctgtgctt cactgatact ttggatcttt ccgatgcttc
     7501 tccagcctaa aatcacagct cctaatgcgg atgcttctgt gacagtaggg aaaacaagcg
     7561 ggtaacccag tacatcagcc atcatctgac gaaaaatcgg agattgagca aacccgcctg
     7621 tagcacggat ctctgtgagc tgattttcct ggcaaactcc ttttaaaatc cgataaaggt
     7681 tgagacagat cccttctaga atcgccttca tcatttcttt ttctgtatgt tgccgctgta
     7741 aaccgataaa actgccaaac gcatctgcgt cccaaagcgg tgctcgctca ccaagtaaat
     7801 agggatgaaa aatcagacca ttggcacccg ctggcacaaa agcgatagcc gaaagcagtg
     7861 catcatatgg attttctcct ttttctttag cagattgaac gacttcctgt aaaaatgtat
     7921 gccctgccca atcaaagatg ccagcaccat tgctagtcgc tcctcccact acccaatgtt
     7981 tctgatccag aacataacaa aacgtctcca tttctggatg gaactgaggc tgagtagtaa
     8041 taaaacgaag tgctccgctc gttcctacgg tcaaagcggc gatcgtatca ccaaaagcac
     8101 ctaaccctag attagaaagc ggcccgtctg cccctcccaa aacaaatgat atatcatttg
     8161 gcaaacctag ttctgctgct gtttttgatg gtagacctgt tacttgatag gtggaaggaa
     8221 agacttgcgg caattgctct attcgaatgt tcaagtagtc aagcacttct tctgcccatt
     8281 ggaattcatg gatatcaaaa tatccagttc ctgaagctgt tccgtagtcg ctgatcagtt
     8341 cgccaaacaa tctataaaag atatagtctt tgataccgac aaaataagca gtttttttga
     8401 ataattcagg ttggctgttt tgcagccact tgattttgtt caatggtgtc attggatgaa
     8461 tcggcgtccc agtctgccga taaaattctt tgccaagcac ggtatatttc agtttttctg
     8521 cttcgtccgc tgctcggtta tctgcccaag tgatcattcg agataacggt gttttctctt
     8581 catccaacaa tatcaggcca tgcatcgcag aggagaagga gacaaattga atgattgtgt
     8641 ctgaaggcaa ctgtttaatt acttctttta taacggtgca gacaccttga aagatcaatt
     8701 cctgatcttg ttctgccatc ccttgtgttt cttggatcaa agggtagcga aaataagcgg
     8761 atgctgcttc ttgggcttca tctgtgaaag caactgcttt ggtttgtgtg gttccgatat
     8821 ctaatccgat tgaaacgttc attttttcac ctcaaatttt atgtatgtac aaaaatttag
     8881 tttaagcttg cgtatcttgg ttttgaaaag ggggagatgg cgtgttactt tattttatca
     8941 ttggttgctg tatcggatca tttttatgtt taaccgccca gcggattccg ttaggtcact
     9001 ctattattta tcctagatct cattgtgtca aatgctgtcg ttcgctttct tggtatgaat
     9061 tgattccgat tctctcgatc atcgtccaac gatttcgctg ccgctattgc aggtgtcggt
     9121 tgcccttcta ctatttgttg gcagaagcct tatgtggtgg tctttttgcc tggttcttta
     9181 ctttttcttc cgcaagaaat ttttcgacgt tcatatggat gctttcggct ttgctatttt
     9241 cgttgatgga tttattttac ttcatggtcc attctcacac gctattctgt tcttgggcaa
     9301 ttttatggat tttttggttg caggccggcg tcttccaatg gcaaagtgtg ctgttaacgt
     9361 ttatcgtagg cggtgtgtgc cttcgctatg gtcaatccta tctcggagct ggcgatactc
     9421 tgttgatgct ttcttggagt ggtggcttgt ctctagaaga gttgcttcag atcttgtttc
     9481 ttgctagtct gtttggaata tccgtttttt ctgtttactt tatctgtcat aaaaaaaagt
     9541 tggaaaagct gcctttcatt ccttttttga gcagtgcgtt gctgattgtc cttcatctta
     9601 ggtattgaaa aaaggttgtg acaaacgact tgtcacaacc tctgatatat agtgttctct
     9661 taccaaatcc ttgtgacttg gagctaggcg acaggttcac aacctctcca ctaaatggtg
     9721 ttcaatcagc tgaccctcag tattagctca aaatgctggt tttacaacct ctgatatacg
     9781 gtgttccata agtagctttt tcggcttctt atttcttgac gccccaatgt cgacgaagga
     9841 aacctgcacg tccagaacct tctcgataaa gattgtaatg gagcttgttt ttcttgtaat
     9901 aatcctgatg gtaatcttct gcaggataaa attcgcttct tggttcgatt tttgtcacga
     9961 ttggcttatc gaatcgcccg ctgtcttgca atgcttgttt tgaacgctct gcaatatttc
    10021 gttcttcttc atcattatag tagatcactg gacgataaga atcaccgcga tcagcgaact
    10081 gtcctaatgc gtcagtcgga tcggtttgct gccaatagat ttccaccaac tgatcataag
    10141 aaataacttc tggatcatat tcgatctcta ctgcttctgt atgccctgtt gtgcctgttg
    10201 ttacttgttc ataagttgga tttggtacat gcccgccagt ataaccggat gtcacagaaa
    10261 tgatccctgg ctgctcttca aatggtttga ccatacacca aaagcatccg cctgcgaaaa
    10321 ctgctttttt tgtcatataa aatccccctt ttttctcatc ataccttgat ttccaaaagg
    10381 aggataacgt tttgcttgtg acagaaaaaa cggaaactat tatatacgtg atacggcttc
    10441 tgataaatgc caaaacgaac gtacttgatc aaaaacggtt aaatcaggaa tcacatattc
    10501 agcagaagga agatttatgt tttcacctat tcccaataca tgcatgttac cagccaaagc
    10561 tgcttgacaa ccagcttctg aatcttcaat gaccaagcat gcatttggcg gtacattcaa
    10621 ttgctgtgct cctttgagaa aaacttctgg atcaggtttt gcttttgata cttgcgtgcc
    10681 gtcaataagg acatcaaaat aacttgtcaa attcgttttt tctaaaatga ggcgtgcatt
    10741 tttgcttgct gatcccaatc cgatcttgat gtttgttttt ttcaagtact caagaacagc
    10801 tattgcacca ggcaaaacgg atgtttcatc cattttttga atcgcttgaa gatatagatt
    10861 gtttttttgc tcagcaaagg ctgatttctc tttttctgag aatttctgtt ccatttttcc
    10921 aaatgacagc aatcgctcta gtgactcggt tctggatatt cctttcagtt gctcgttttc
    10981 tttctcagtg aatggaatgg acagctggtt agctaaaacc agccacgctt cgtaatgata
    11041 acgagctgtg tctacaagaa cgccatctaa atcgaatagt gctgctttga ttttcatcga
    11101 ttacctcctt gaaaatgaac gacttgaagt aaagatgcga tgtttttagc tgtgcgatga
    11161 agattatcag tggcttgctg taaagcttct tgtaaaggca cagctgcagg aaggatcgga
    11221 aaaacggccg aaatgccaac atctgctgct ttttcgcttc ctttaccaac acttccgcaa
    11281 atagctatca caggaacgcc ctctggtact cttctagcaa tcccaactgg cgcttttcct
    11341 tttagacttt gtccatctag acgtccttcg cctacgatta cgaggtctgc ttgctgtacc
    11401 cgtatcgaac tccagtaaat ccaatacgta gtcgatgcca gagactattt tccctgaagc
    11461 aaatgctaac agtcctgcac ccattccacc accagcacta ctgcccgatg cctcgattac
    11521 ttgaggggca aatctcatat aaaaatcatg catggcttgg tcagccactg ctaattcatt
    11581 ttctttcaag cctttttgtg gtccgaaaac aaaagaagcg ccttcttttc cgcataaaag
    11641 attagtaaca tcagtaatga cagtgatttt ggctttaatc agctcaatag gcacgttcgt
    11701 tttatcaact gtagcaattt tacctagatt ttctcccagt gcttctactt tttgattatc
    11761 ttgatcgtaa aaagcataac ctagaccttc tgccatgccg atgccgccat cgttggtact
    11821 acttccgcca acgccgatga tgatgtgtcg aacaccttgt tgcaacaatt gtcgtatcag
    11881 ttctcctact cctcgcgtgg ataacctaag tggctgttgt tggtttagtg ggacatcttt
    11941 caatccgacg atttctgcca tttcaaaaat cgcagtttga ccgtctgaag cgtactggat
    12001 ttctttgttt ttgccaaatg cattagtaac gactgctgtt tgccgcttca accttaaact
    12061 gtctgctaat gatgaaaccg ttccttctcc tccatcgcct ataggtagca gatcatattc
    12121 agcctgaaca aaaacttctt gaaaacctga ttgaatggct tgtgctgcct ctaaggctgt
    12181 cagactttct ttgaaagaat ctggcgcaat cagaatacgc attattttcc cctccgttcc
    12241 aagatcagtt ctttttccag ctggtattgg tctccattga caaaaatagg taatgtttct
    12301 ttcgtctctt tttttattac tatttgtttt tttgtcaaaa caaatagcaa cctgtgattt
    12361 ttccaaataa aaggaaaaga aattttttcc catgctgaag gaagtcttgg agaaatagaa
    12421 agagttccat tcgttactgt aatacctgaa aaaccaaata taactgctag ccatagtgct
    12481 cctaatgaag cagcatgaat tccgtcatct gatgaatgcg gatctggtcc taaatcaatc
    12541 aggcacgctt cttggaataa atgatacgcc cattccattt cttggatacg gcaagcctct
    12601 atggcgtgaa tcgctttact caacgatgag tcgtggattg ttttgttttc atagtaatgc
    12661 aaattcttag aaacgattgg ttgagaaaaa tactcaggta ataagtataa cagcatgaca
    12721 agatctgctt gcttgctgac ttggagttca tttacttcgc tacgggcata atcaagtaaa
    12781 atagactggc tgccaggacg ttctttgtaa gtggtcaaat caataactgg cttactgaga
    12841 tacgtgtcat cttgcggaat cagctgttct ttgttaggca ctggcaaata taacttatct
    12901 aaaaaatttt gacattcttt caaaaaaagc ggatcgccag cttgatattt aacagctaag
    12961 gccacattat aatgcgccag atagttcgta tatgcattat tgtcgatata ttctgtgtat
    13021 tcatctggac caatgactct gtgtatctct aaatgatcat cgacttttac agctctgctc
    13081 agccaaaaag ctgctgtttc atgaatgagc gtttttccct ttgtttctaa aaacgattga
    13141 tcctctgttg cttggacata ctcttgaacg gcataagcaa ggtctgcact gatatgatgt
    13201 tctgcggcag ctgaagcaac ttcttgtctt gttccggttt tgatattcaa tgcagcaaat
    13261 ttgggtgtct cttcctgacc agtgtgtgcg ctttcccatg ggaaaagtgc accttgatag
    13321 tgataatctc ttgctttttg ccgtgcgcct tctaatcgat cataacggta cagcagcaaa
    13381 ttctttgcta cttcaggaaa ctgatataaa aagaaaggca ggataaaaat ttccgtatcc
    13441 cagaaaacat gccctttata accttcgcca gttagtccct tcgcccctac actaacactt
    13501 ggatcattgc ggggagtcat aatctgtaaa tggtaagcag cgaagtccat cgctaactga
    13561 tcgaaagaag aatcgccttg gatcgttatc cgatgctgat gccaaaaatc tgtccaataa
    13621 gacatcgact gctctaaaat ttctgtataa ctaacgcttt tctgggcttg ggcaatactt
    13681 ttcttaaacg ggtctgtttg ctgaagagag gtagagagca cgatgatctt ctccagcgta
    13741 aaggacgtat tttttctgat cttttctgaa aaggaagcgg tgatccggcg attttttgct
    13801 tggaatacac ctgctttatt gaatttagct gcaatcccaa tatcaatttt actttctgtt
    13861 gtctggtagg atgcactgat caaatcgtca ccaaatactc gcagttcttt ttcaaccaac
    13921 tgctgtgtac caaaattggt ttgctgtcca tcgatacccg ttttcacatc tacttggcag
    13981 tcttcggtca acggcttgat gaccactttc agggctgcct gatggagatt attttgatca
    14041 gcaacacgac aagtaatgac ttccactttt tttccttgag cagtttcaat gagcgcatag
    14101 cgtttaagct ctcccatttc taaatctagt gcccgctcgt atgcaagaac tttcatcgtc
    14161 tcaagagaaa aatgttcacc gtcgattttt atttcccatc tgatgacatc tgggagattc
    14221 actaactcgg ctgattctgc tcctaaaggt cggttatata caccagctgc aaacattccc
    14281 cttacttgat tccgatagtc ttcctcctgg cttcctctga taccaaaaaa tccatttcca
    14341 atggtcatct gactcgcata cttattgata tactctaaat caaactgttt ttcttctact
    14401 ttcataaggt aataacttct cctgtttctg ccgaacgata taaattttcc accagattct
    14461 ggatgacata tccttgccag ccatctgcaa tcatctgagt ctggtcaccg agcgcccgat
    14521 tcacaaaatg agccatactt agttcatgtg ggtcattaac tggcgtggtc ttttgtaagg
    14581 aaaccagctt tccatctaca tcttcgaata gttcgcctgg atacagatta gcacctgcct
    14641 gatcgccaca aaaagccaca ttcagtttgt cttctctgat attcaaagca aacgaagtat
    14701 tcagttggat gatcttgccg ttttctaatt ccagtgtgcc aaaaattgca tcttctactg
    14761 tgaatttgct tggatcccat ttcccgaatt tccctgaatt ttttttcgta ccaatttttt
    14821 ggaagctgta cgcccgaacg ctttttactt taggaaatcc agtaatatac atcgctgtat
    14881 caagcatgtg aatgccataa tcgatcaaag gcccgcctcc ttgaagttct ttgtcgataa
    14941 acgttcccca gcctggaaca ccagaccgac gaagcgcatt cgcttctacg taataaatat
    15001 ccccgagaac atcaagatga ttcttgatca ttgttgcttc gtcagaaaaa cgatgctgga
    15061 atccataagc caaaatctgc ccgtttttat cggctgtctc tgccatcttt cttgcttgat
    15121 cagctgtcat agctggtggt ttctcgcaca tcactgaagc attagcttcg agggcagcca
    15181 atacatgttc gaagtgaaag cgattggctg tacagacact cacgatatcg ggagaaatct
    15241 cattcagcat ttgtgtaact gatgtatacg catgagaaaa tcctgtacgt cggcaaaagt
    15301 cttctgctcg ctggctgact ggatcaacca cagcggccaa ttctaagaca tctgatcttt
    15361 tttgataata agcagcatgt actttttctg ctacttgtcc agcgcctatg attgctactt
    15421 tcttcattta tttctctctc ctttgcttat ttacttattg ttattctttc tctattcttt
    15481 ctctaaatca tttaaatgac gcgctgtttc cagacagttt ttcaagtatt gcaatgattc
    15541 ctgataaatt ttcacttcat tttctcctcg caaacgacat tcatatacca tataaccttc
    15601 atactcattt tgaagtagcg tttgaaaatg gcgagtaaaa tcaattgcgc cagatcctgg
    15661 ttggtagcga tgattatctg ctaaatggat atgacccaca tactcttttt gcgtagtcaa
    15721 tgcttttgaa atatcatctt cttcaatatt catatgataa aaatcagcga tgatctgcac
    15781 atgtttcaat tgattagagt caatgtaatg acgcgcatcc gctaacaaat tgatcatatg
    15841 gtcttggtat cggttcaaag gctccaaata aataaccgta cctgtttctt cggctacttt
    15901 atctaaataa cgaagtgatt cgctgactgc tttatagtct ccttctttgc ttcggggtga
    15961 aaccatcggc ggtaatcgat aagtgaacat tccccaagct gctgggataa cgattccttt
    16021 gcctccaacc tcgcttagtg cacgcaaaat ctcagcaatt tgacgtacac cattaagacg
    16081 ccgttcttcg ataaagtcac cgatccaccc atcgtagccg ttacaagctg tcactactgg
    16141 gatccctgtt tctttgattg cctgtttgac tgtgtcgata ttttctatta acaacttacc
    16201 gtcgatttcg tattcttcaa atccacagtc tttgataaat ctaaattttt ctaaaatgtc
    16261 tcttgggaaa aatgcttgat cttgcgtacc gaatttcatt gttctcctcc tcggacttga
    16321 acgcccattt tgatactttc ttctgggtgc tggtctacat aacgcatgta agcttctgcg
    16381 ctttctgcaa atggcacaac tggatcaatg atttcttcac aatccaagta accgttcatc
    16441 aataattccc aacatgtgtc ctcgattcgt ttacggttcc atcttgggta atctgggttt
    16501 ggttcactag atgctcgagc aaagacgatt tttgcattat tgaaatgtgc ttcgcgacca
    16561 agattaaacc cagctggaaa aggtttagca aaggcaacat aagaaatgat cccgccatag
    16621 ccgatccctc ttaaagaagc ttgtaatgcg gcagcactgc cactcgtttc aataactgaa
    16681 tctactccac gtttatctgt caattccttt agacgaaaac cgacatctgc tttcatagga
    16741 tctagcgtgt aatcggcacc gtatttttct gctaattctc tacgctgcgc tatgggatcg
    16801 atcccaacga tggtagtagc acctgctttt ttagctaatt gaatcgcaat ttgcccgata
    16861 gcgcctaaac cgaagattgc tacagcatca cctgctcgaa catgtgcttc ccggatacca
    16921 cctaaagcga attgagcagg atcgtaacat actgcatttt tccattgatc caaccgatca
    16981 agtttacgta gtttataatt atcaacaccg tttgtaatca gcgtttcacg aatgggtcca
    17041 taagtgcaga ctaactctcc tttttgatac tctgtcacca aactgcccgt ttcttcgatc
    17101 gtaccgacaa tcatatttcc taattgaaat tcgccaaata ccacaccgcg ttggcttcct
    17161 tcttctcttg gcaagaatag gcgccattct tctgaaaatt cttcatcgat aaatggactt
    17221 aatcctctaa agtcgacaat ttctgttcct ggttttggag tagcgaaaat tactcggata
    17281 cgtacttcgt tcttttcgat ctcacggtct tcgtaatctt tgaatccggc tattcttggt
    17341 tctaatgcaa ctaatttttt catcttttct ttcctctttc ttttcttttt atccttttac
    17401 gccgccttcg actaaatcac ctttaataaa tcgttcagat aacgcataca taatgatgac
    17461 tggtaaagcg gtcaccaatg aagcggccat cattcgtccc caaatgtagt ctggtgtact
    17521 gaataatgtg ttcaaaccga ttggtaaagt aaatttttcg gaggtcgaca ggaaaatcga
    17581 agcaaataaa taatcattcc acgaaaccat aaagcaataa acgaagacag aaatgattcc
    17641 agaaatagcc aatggtataa tgatccgaat aatgatctgg atccggctaa gaccatcgat
    17701 cattgctgct tcttcaatat cagtcggaat cgtgtcaaaa taacttttta gcatgaatat
    17761 cgcagtagga agtgtttgaa cgaccatcgt gataatcagt gctgtattgg tatcatacaa
    17821 acctagaccg gaaatgattt taaataatgg aacaacgatc aaaataccgg aaaacatata
    17881 aacggtgtaa aagctagcat tgattttcga gcgagctttg aagcgtagtt ttgacaaagc
    17941 gtatgccccg ctgatcccaa tcactactgc agttacggag gctatcaagg agatcactaa
    18001 actatttttg aaatacatga tgaatggaaa aatctcagca ttgaaaatat cctgataatg
    18061 ttcaaaagtc cattctttcg gaaaaatagt ttgtgtcgtt gcaattgctt cttgtgaatc
    18121 cttgaatgat gtcatcagca tgatcaaaaa tggaaacaaa ttgacagcta atagcaacaa
    18181 aatcgtcgcg taaaataaga ttttcctgct ctttttattt ttcatttcaa gtccaccttc
    18241 tttcgtgaga gcaagacgac cgctgcaata atgatgaaca atagaatcga tatagctgct
    18301 gcttttccaa gatcattgaa cgcaaaggct gtctgataca aataaacgcc taagatattg
    18361 actttattcg tcagtagata gacatctgta aacatataga acatccagat agatcgtaaa
    18421 acaatcacag ttgctagtac tggtttgatt gccggcagtg tcacgatctt gaacttctgc
    18481 caagcatttg caccgtccat ttcagctgct tcataaagcg ttttgtcgac tgtttgcaaa
    18541 atagccaaaa atgaaataaa cgcatacgga tagtatctcc agatagcaaa caaaacgacc
    18601 ataaagaagc tagcaactgg ctggtcgaac cacagcggtg cttcgttgaa aagctgcaac
    18661 ctatctacta acagatcatt gacgattcca taactattat tgaacatata tttccaagca
    18721 aaaatcaaag aaatagatgg cgtaacataa cttaataaaa tcagtgaacg caccgttttc
    18781 ctaaatctga acttgcggtt aagcaaaata gctacggcta atcctaaagc tgtactgcct
    18841 gctacaacta agaatgtgta agcaactgtt aaacctaaag aacgataaaa ttcactatca
    18901 cttaaaattt caagataatt gcttaatccg ataaaaacgg cgtctgagtt aggattcagc
    18961 ggcatatcga aaaaactgat ctgaatattg gaaagcattg gaatcagcac taaaacagct
    19021 aataaaagca tgcttggtgc taaaagtccc atggctaatt ttaagtcaga atgtttcctt
    19081 ggacgattca ttgaaacctc cccctgataa tctgccaata gctatctact tttttcgaac
    19141 accattggca gaacttcttg ttatttcgta tttttttgtg cgtcagctaa agcttgatcg
    19201 acatcttcgt ttccgacagt tacttggttc actgcttttc cgatcacacc tgagcttgtg
    19261 atatctccca ttttcgtgaa attcttttcc ccgactagtc caaagacttg tacttcatca
    19321 aaagcactag caatctcaga tggcagctcg ccaaaagact tgatgacttc attttctttg
    19381 taaccatcca gttcgactac ttgtttattc actggttgag caccaccagg agacatcaag
    19441 acccactttt ccatgttttt cggttgagat aagaaagctg tgaatgcttc agcagcctct
    19501 ttttgtttct cgtctagacc agaagaaatc gtcaatccag atactgtgcc atagacagct
    19561 tgatcttttt gtgttgggat agcaaaaccg atattttctg agttccccgc ttcataaaca
    19621 gaaggcaaaa tgtaagttga atagattgcc attggtgctg ttccattcat gaaagcatct
    19681 ttgatttctg tcacatcatt agagcctggc atcgtgtatt gggataagtt ttgataaaac
    19741 gacaatgctt ctctcatctt ttccgtatcg atcgttacct cgccttcatc atccaaaaca
    19801 tttgctccat ttgacaaagc aaattgagag aacgcttgct cactcattgt tccttcagca
    19861 gtaggcatag caattccata ttgtttattc tctttatctg tgaaatgttg agcaattttt
    19921 aaaatatcat cccaattttc tggttctgaa aaaccagctt ctgataattt ttctttgtca
    19981 taccaaatac cttgaaccca gccgctaatt ggtgcagcaa tatagctttt tccatcttct
    20041 gaacgaacaa ggtttttggc tccgtcataa taattatctt ctccagcttc ctcgataacg
    20101 ttttggactg ccgtctgatc aatcagttca tctttatcca tcactttagc aaaatcctga
    20161 ctgacttcca ttacttctgg taatttaccg gaacgagcta acgtaacgat ttttgtattg
    20221 aacgctgatt cttctaccgg cacttgcttg attttgatgt ctggattttc tttttcaaaa
    20281 tcagcaacca gttcattgat cacacttaat cgttcctgtt cgacagaaga gtgcatgaat
    20341 tgaatcgttg tctgttgtga ttcgttagag ctttgacttt caccacaagc agtaagaaga
    20401 aatccagtag ctagcagaca ggtagtaaca ataatttttt tcattttttt ccacctctta
    20461 ttttattatt ttcagccaca tatattcata cggctggaat atcaactttc gttcttgact
    20521 gcaatggata atttgtccag aaaacaggtc taggtaatct ccttttggta aaagataacc
    20581 tgctgattga ttggaaaaat tatggataac taagactttc tcttccttcg cttcgcgaat
    20641 aaaactgata aaagaatctg ctgagtccag taagtaaatc aaactattcg gatggaaggc
    20701 tttttctttt tttcgaatag atagcatctg ggtcaattca ccatatactg ctgttcttaa
    20761 tggatctgtc tgcaactctt tctcaatatc tgctaacaaa aatttttgcc gattgatttt
    20821 tcgattctct cctgtttttt ctacgccttt gtaatcattt cgacttccca gcacactttg
    20881 aatataaatt gccggcacgc ctggtaacgt taccaaaaat gaatgagcag ctaaaaagcg
    20941 tttgcttctc cattccgtcg tatctgttgg agaacttaac gcatctagat acgtagcgtt
    21001 tatctcatat ggactggtcg ttccatctgg gtttttcttg tagtttactc gggcaccctc
    21061 tttcttcagc tgttccacta attcaaggat cgttttttcc ggcagaatac ctcgtaccgg
    21121 attcaatccg ataccgtcat gggaggctaa aaaattaaaa aaagttgttt ttttcgatgc
    21181 gaaatcgatg gtttttaacc attctttcaa cttacttgta ttacccgaac gaatcgcttg
    21241 aagggtcaaa ggtggtagcg aaaactgata gaccatctgt gcttcattct cgccattccc
    21301 aaaataactg atattatctt tgtgtggcac atttgtctca gtgatcaata ccgttcctgg
    21361 agctgcttca tcagcgattg cacggaataa ttggatgatt ttatgcgttt ctggcaggtg
    21421 tatacaagaa gttcctagtt ctttccataa aaatcccaca gcgtccaagc gaataaatga
    21481 agcgcctttt tctaagtaaa acaaaagaat atcgatcatt ttcaataaaa cttctggatt
    21541 tttaaaattc aagtctactt gatcttcgct aaaagtcgtc catacgtgtt tttctttccc
    21601 gtttttgtca atgaacgttg taagtaacgg gctggtcctt ggtctagtca cgctgcttgt
    21661 atctgtatcc agtggcaaat caataaaaaa atctttgtac gtatcattca agtttaaata
    21721 ttcctgaaac caagtacttt cggcagacat atgattgcag acaaagtcga acattaaccg
    21781 tgtttcgctt ctcatttctt ctatatcttc ccatgtgccc aaacggtcgt tgattgcctg
    21841 ataatttaca acggagaaac catcatcaga tgtatatggg aaaaatggca agaaatgtac
    21901 aactctaaat gtatctgcca aatacttttg ataaaatttc ttaaatgtac gcaaagttgg
    21961 ttgctgctct tcaaaaaatt gatccccata agtaatcaag aaaatatctt cttcgtccca
    22021 atgcagtttg cctgcctggc ctttcttctg ctgataaaca ctgacttttt gttcaatcat
    22081 agaggcggtt ttctcagaca aatctgagtc gcgataaatc gcttgtaaaa gttttgtata
    22141 catcggattc ccctttcttt tttgggagcg ttcccaacga tttgatcata ttatggaaaa
    22201 cgcttactgt caatagcatt tttttaaata attttgatat acacaaaaat acaaataaga
    22261 aagcttatgt atcaataatt aatagcttct taaaaaaata tggtctctca tgatcatgca
    22321 agctattcct aaattttcaa aatcatagac aaaaaagaat gtctattgta ctatggaatt
    22381 attctaaaac gctcccaaaa aggaggtgca tataaaattg aaacctacta tttatgacat
    22441 tgcgaaaaaa gctaatgtct caaaatcaac tgtctccaga gtattaaata accagccaaa
    22501 tatctctgat aaagcaaaag caagtgtact tcaagcaatc aaagaattga attatgaacc
    22561 gagcaaaatt gcaagaggac tgtcaggaaa tggttttgac gcgattctag cattatctca
    22621 tcgtacttct catacgacct atggcaatcc ttttttttca gatgttattc aatccatttc
    22681 tgccgtttct gaacaaaata acttcgactt gattctacaa acggcaaaaa caccagaaga
    22741 agagctagaa aaatgcgcga aaaagatcca agaaaaaatg atccgaggaa ttattatttt
    22801 aagctctacg atggatgaaa cacttctttt tgaattggat caatacaata ttcctattgt
    22861 ggtaatcgga aaagtcggaa acgactacac gaacatctac tcagtggaca cggataattt
    22921 ccaggatagt tacgatttgg tggaaacact gatcaagaat ggacaccgtc atatcggctg
    22981 tctccatgct ccgacagaag tttatgtatc caatgatcgt ctcaatggtt accgtcaatg
    23041 cttatttgat caccacctag atatccgtaa tgaatggatt atagacggcg gctttcgctt
    23101 agaagatagc atggcagcaa tgaatgattt aatgaagcta cgagaaagac caactgcgat
    23161 tttttctacc gatgcattaa aatcattgag tatttacaaa gtggcagaac aatctggaaa
    23221 gcagatacct gatgatcttt cgatcgcagg attcagtgat cccttattgt cctccctatt
    23281 ttcgccacag ttgactcgga tagacattcc gacaaatcag ttaggaatca aagccacaga
    23341 acttttattc caactaatcc accaccaata ccctgaagaa aaaagaatca ttctttcaac
    23401 cgagattact ctcacagatt cgatccaaca acaagaaatg tagaacagaa ttataaaaga
    23461 acagaaacac tgaggataag tcagttactc tgttcttttt tcaatcactc atccctcgtt
    23521 accccctccc ggtattttag cgaatttttc ttattttcca tctgttttag atagctgtgg
    23581 ataactataa tgtttgtgtt aaactatttt ttccacaggg aagaaaaaac tatttttaac
    23641 cacgttgtgt ataagttttt atagttcgtt tttttaaaca catttaccct tatttcaatc
    23701 catgttattt ggggatactt atctctaaaa cataaataga ataacagaca tgtctactgg
    23761 ttttgtttta ttcgaggaat tattcaataa tagctagcaa aatattaaaa ataaccgctc
    23821 tatcttccca tcaatttatt ttgcattcaa aaaatgatct atctttactt ttgttgattg
    23881 acttctcttg gaagatgatc gttccgatac cttaattgga tacgaaccga tgttgttaag
    23941 atcctttccc acttttcttc tagttagaca aattatttta gacaaaccaa aaaagaggtt
    24001 gtgacaataa tttgtcacaa cctctttttt aaaatatcta ttttgtttga ttgttcattg
    24061 cgtcttctgc agccatttgc gcttcaatat ctgaaatact gtagacattt tcgcttgcta
    24121 caccgacttc ttttggttcc atgtcacgat aacgttgcat accagtacca gctgggatga
    24181 tcttacctat aataacattt tctttcaaac caagaagagg atctttctta ccgcggatcg
    24241 cagcatccgt caagacacga gttgtttctt ggaatgatgc agcagataag aaactatttg
    24301 tttctaatga tgcttttgtg atacctagta agacaggtcg agaagttgca ggaacgcctc
    24361 ctgagactag cgtattgtag ttttgatctt taaagtctgc gatgtctaat aatgtacctg
    24421 gtaagatatc tgtatcacct ggatccatta cacgaacttt acgcagcatt tgacgaacca
    24481 ttacttcgat atgcttgtcg ccgatttcta ccccttgcat acggtaaaca cgttgtactt
    24541 cacgaagcaa gtagttttca acagataata catcgcgaac ttgcaacaat tgttttggat
    24601 cgattgatcc ttctgtcaat ggtgcaccac ggtggatcat atcgccttct gctactttca
    24661 tacgtgctgt ataaggaaca gtatacgtac gtgtatctgt ttttcctttg attgttactt
    24721 ctttggtacg tgttgcagga tcttctgaga tatcgatgac atcccctgtt acttctgtga
    24781 tcactgcttg ccctttcgga ttacgtgctt caaagatttc ttggacacga ggaagacctt
    24841 gagtgatatc gtctccggca accccacctg tatggaatgt acgcatcgtc aactgagtac
    24901 caggttcacc gattgattga gcggcgatcg taccaactgc ttctccgact tcaacgtcag
    24961 agccagttgc aaggttgcgt ccgtaacaat gtttgcagac accatgtttt gtattacatg
    25021 tgaagacaga acggattgtc actgtttcga cacctgcatc aacgatttgt tttgcgatgt
    25081 cttcggaaat caattggttt cctgcaatga tcaattcatt tgtttcagga tgacgtactt
    25141 ctttacgggt gtaacgtccc actaaacgat cttctaatga ttcgatgatt tcatttccct
    25201 cgcggatggc ttggatttca agacctcggt cagtaccgca atcttcttca cggatgatta
    25261 catcttgggc cacgtcaacc agacgacgag tcaagtaacc tgaatcggca gtcttcaagg
    25321 ctgtatcggt catcccttta cgagccccgt gagttgagat aaacatttcc aagacggata
    25381 gtccttcacg gaagttcgaa atgattggca attccatgat tcgaccatta ggagcggcca
    25441 tcaaaccacg cattccggca agctgtgtaa agttggaaat gttaccacga gctccagaat
    25501 cagacatcat gaagattgga tttttcgctt ccaaaccttc catcagtttt tgttggatgc
    25561 tgtcttttgc agcattccaa acagcaatga cacgttcata acgttcgtca tctgtgatca
    25621 gaccacgacg gaattgtttt gtaatagttt caacttgttt atgggcattt tcaatgattt
    25681 cttgtttttc attcagtaca ctgatgtcag cgatccctac tgtgataccg gcatgtgtcg
    25741 aatgtttgta ccctaagtct ttcatacggt caagcatctt agaagtttct tttactttga
    25801 atcgtttgaa gacttctgcg atgatgtttc ctaagttttt cttcttgaac ggtaatacta
    25861 attcttgctc tttgatatgt gcaggaatat cagtaccagc ttcaacaaag tatttgtccg
    25921 gtgtttggac ggtcaagttg aagtctgttg gttcattcag ataagggaat tcaggaggca
    25981 tgatctcgtt gaagatgatc ttaccaactg ttgtgatcat cgtacgttct ttttgccatt
    26041 cagtaaatgg tttttcacct aatgagttag ggttcacacc gatacgtgaa tgtaaatgaa
    26101 catatccgtt gcgccatgcg ataacggctt cgttttgatc tctgaagacc attccttcgc
    26161 cttcgcgtcc ttcttcttcc attgtcaagt agtagttacc tagaaccata tcttgagaag
    26221 gagtaacaac tggtttacca tctttagggt tcaagatgtt ttgagcagct aacatcaaca
    26281 tacgtgcttc tgcttgtgct tcttcattca atggaacgtg gacagccatt tggtctccat
    26341 cgaaatcggc attataagct tcacatacaa gtggatgcaa acggattgcg cgtccttgta
    26401 ctaaaactgg ttcgaatgct tggataccaa gtcggtgaag cgtaggtgcc cggttcagca
    26461 atactgggtg ttccttgatt acgtcttcta aaacatccca tacttcgtct tcttgacgtt
    26521 cgattttacg tttcgcattt ttgatgtttg aagctagttc gcgttgaaca agctcacgca
    26581 tcacgaatgg tttgaataat tcaatggcca tttcttttgg aagtccacat tggtacatct
    26641 tcaagaaagg tccaacaacg ataacggaac gacctgagta gtcgacacgt ttacctagca
    26701 agttttgacg gaaacgacct tgtttccctt tcaacatatg agaaagagat ttcaatgggc
    26761 ggttacctgg tccagtaact ggacgtccgc gacgaccgtt atcgatcaat gcatctactg
    26821 cttcttgcag catacgtttt tcattttgaa cgatgattcc aggtgcattc aagtctaaca
    26881 aacgtttcaa acggttatta cggttgatta cacgacggta aagatcattc aagtcacttg
    26941 ttgcaaaacg tccaccttct aattgaacca ttgggcgtaa atctggtgga ataacaggga
    27001 taacgtccat aaccatccag cttggttgat ttcctgaagc gcggaatgct tctaaaatat
    27061 ccaaacggcg gattgcacgt gtacgttttt gtccttgtgc agatttcaat tcttctttca
    27121 attcggctgc ttctgcatct agatcaacat tatcaagtaa ttgtttaatc gcttctgcac
    27181 ccatagcagc ttggaattct tgtccatatt gttcacgttt ttcgcgatat tcgcgttctg
    27241 tcaacaattg ttttttctct aaattcgtat ttcctggttc gatgactaca tatgaagcaa
    27301 aataaatgat ttcttccaaa gcgcgtgggc tcatgtctaa tacaagaccc atacgtgaag
    27361 gaatcccttt aaagtaccag atatgtgaaa caggagctgc taattcaata tgtcccatgc
    27421 gttcacggcg aactttcgaa cgagtaactt ccactccgca tcgatcacaa acgattcctt
    27481 tataacggat acgtttgtat tttccgcagg cacattccca gtcttttgta ggaccaaaaa
    27541 tccgctcaca gaacaaccct tcgcgttcag gttttaaggt acgatagtta atcgtctcag
    27601 gtttttttac ttcaccgtaa gaccagcttc tgattttttc gggagaagcc aaacctattt
    27661 gcatactttc gaatttattt acatcgatca aaaggggttc cctccatttc atttaatggc
    27721 aaaccgcaag acggctgatc ttcgaccgcc ttgcagctca tagaccggat tagtctaaat
    27781 tatcttctgc ggtttcaaag ttttggatga catcgtcttt ttcatcttcc acttgttcag
    27841 cagctttctt ttctaattct ttggcagttt gctgttcggc aaattttgtc aaagcatcaa
    27901 cagtgatcaa atcgtcgtct tcatcgtcca tgtcgcgaag ttcgatctct gtttcttcga
    27961 tatccaagac acgcatgtcc agacctagtg attgcaattc tttcaccaat acgcggaatg
    28021 attccggtac acctggtttt ggaattggtt cacccttgac gattgcttcg tatgttttca
    28081 cacgtccgac tacgtcatct gatttgtatg tcaagatttc ttgtaaagta taagccgcac
    28141 cgtaagcttc cagtgcccat acttccattt caccaaaacg ttgtccacca aattgagctt
    28201 tacctcccaa tggttgttgt gtaaccaatg agtaaggtcc gattgaacgt gcatgcaatt
    28261 tgtcatcgac catgtgagca agtttgatca tgtacatcac accgacagac acacgtccat
    28321 caaatggttc acctgtacgt ccgtcgtaca gaacagtttt cgcatcgctg gccataccgg
    28381 cttcacgaac tgtttcccat acgtcttcat cacttgcacc atcaaatact ggcgttgcta
    28441 cgtggatacc taactgacgt gcagccatac ccaagtgtaa ttccaatact tgcccgatgt
    28501 tcatacgtga aggcacccct aaaggattca gcatgatatc gattggtgtt ccatcaggta
    28561 ggaatggcat atcttcttcc ggcataatac gggatacaac ccctttattt ccgtgacgac
    28621 cggccatttt atccccttca tggattttac gtttttgaac gatataaaca cgaactaaca
    28681 tgtttacgcc tggtgacaat tcatctccag cttcacgagt aaagattttc acatcgtgaa
    28741 cgataccgcc gccgccatgt ggtacacgta atgatgtatc gcggacttca cgagcttttt
    28801 cgccaaagat cgcatgcaat agacgttctt ctgcagataa ttctgttacc ccttttggcg
    28861 tgactttccc tacaagcaaa tcgccatctt ggacttctgc accaatacgg atgataccca
    28921 tttcgtctaa atcttttaat gcgtcttccc cgacattagg gatttcgcgt gtgatttctt
    28981 caggtcctaa ttttgtatcg cgggcttctg attcatattc ttcaatatgg atagaagtgt
    29041 atacgtcatc ttttaccaaa cgacggctca tgatgatcgc atcttcatag ttgtaccctt
    29101 cccaagtcat gaaaccaact aaaacgtttt ggcctagagc catttcgcct tgttccatag
    29161 atggtccgtc tgccagagta tccccttttt cgactttctc acccaaatga acgattggac
    29221 gttggttgta gcttgttccg gagtttgaac gacggaattt tgttacatcg tatttatcta
    29281 atgcaccgtt gtcgcggcgt acgcggattt cagaagcatc aacgtattca acgacaccat
    29341 catgtttaca taacaaagca gctcctgagt catgcgctga tttgtattcc ataccagtac
    29401 caacccatgg tgcttgagga ttgatcaacg gcactgcttg acgctgcatg ttggcaccca
    29461 tcaaggcacg gttggagtca tcgttttcca agaaaggaat acatgctgtc gcaacggcaa
    29521 ctacttgttt aggtgatacg tccatgtagt ctactttatc aatagatact tctaagtttt
    29581 cactttgagc acgagccata acaacgtctt gagcaaatgt tccatcttca ttcaatgggc
    29641 tgtttgcttg ggctacgatg taatggtctt cgatatcagc tgtcaagtag tcgatttggt
    29701 cagtaacacg acctgtttca cggtctacac gacgataagg tgtttcgata aatccgaatt
    29761 tatttacttt cgcataactg gacaaactat tgatcaaccc gatgtttggg ccttcaggag
    29821 tttcgatcgg acacatacgg ccatagtggg agtagtgaac gtcacgaact tcataaccgg
    29881 cgcggtcacg agtcaatccg ccaggtccta aggcgaaaag acgacgtttg tgtgtcaatt
    29941 cgccaagagg gtttgtttga tccatgaact gtgacaactg agaagaacca aagaattctt
    30001 tgatacttgc cacaactgga cggatattga tcaattgttg aggtgtcaat gtttcagtat
    30061 cttggatcga cattctttca cgaaccacac gttccatacg tgctagcccg atacggaatt
    30121 ggttttgtaa aagttcaccg actgaacgga tacgacgatt tcctaagtgg tcgatatcat
    30181 cgacattgcc gataccttcc atcaagttca agaaatagct cattgaagca atgatgtcgg
    30241 ctggacgaac cgtttttaca gctgcttctg gatagccgtt tccgatcacg tttacttcac
    30301 gttcagggtc tcttggtgaa aatactttga tgacttggac agtcattgga tctgtgacca
    30361 caccgtcttc tgatggatag taagtcactg aatttaggcc attatcaatg aaaggagcta
    30421 gtgtttccat gacttggtga gtcagaactg ttcctttttc aacgatgatc tcgcctgttt
    30481 ctggatcaac taatgtttca gctaatgtca gattcaatag acgtgttttc aaatctaatt
    30541 ttttgtttac tttgtaacga ccaacgtttg ctaagtcgta acgttttgga tcgaagaaac
    30601 gagcattcag caagttacgt gagctgtctg ctgtttttgg ttcgcctgga cgcaaacgtt
    30661 cgtaaacgtc tttcaaacct tcttctgttc ttgagtcgct tgcgttttta tgcaagtctt
    30721 tttcgactgt attgcgtaat gtttcgctgt cgccgaagat ttcaaagatc gtatcatcgg
    30781 aaccaaatcc taacgcacga actaatacgg ttaaaggaat cttacgtgta cggtcgatac
    30841 gtacataaga gatgtctttt gcatcagttt ccatttctag ccaagctcca cggttaggga
    30901 taacagtaga accgaatcct tcttttccgt ttttgtcgac ttttccatgg aaatagacac
    30961 ctggtgaacg gactaactga gaaacgatta ctcgctctgc cccgttgatg atgaatgttc
    31021 cttgttctgt cattaatggg aaatcaccga agaatacttc ttgtgctttg atttcgccag
    31081 tctcgcggtt tgtcaaacgc aatgttacat gtaatggtgc agagtagttt gcatcatgcg
    31141 cacgagcttc tgctactgta tactttggtt ctttcaattc ataatctaca aattccaaag
    31201 atagattgcc attgaagtca tcgattggca aaatgtcttc aaacatttct ctaagtccct
    31261 catctaagaa ccattggtaa gagtctgttt gaatttcgat caaatttggt aattccaaca
    31321 cttcactgat tcttgcgaaa cttctacgtt cgcgatgttt tccgtatttt actacgtgtc
    31381 cagccaagct cttcacccct ctaaaatgtc attcaaaaag actacccgat caattgttac
    31441 aataatattt caaatattat ttttaggtaa caacagacat tttttgcggc ttttaggcaa
    31501 aaaaaaacca aaaatagaac attctcttga aaccttactt cgtgagcttc tacttttgtt
    31561 tccttatatt aaagccgaaa cggacaatat ttcgtttctg ccttttcttc atcagatagt
    31621 ttttgcaact tcatatacta cacttatttt ctataaaagt caacacttcc tggcgtttct
    31681 tctgcttttt cgcaacattt tcttaatgtt ttcaatttta tgttttcaat tatctgacaa
    31741 ttcttaattg acagaccttt ttatctcggt tatactttag aaaattcatt ttgtggagga
    31801 acttctatgc gaaccaacat caaccaaatc gcaccaacac aactgaataa cttttacttt
    31861 agctacttta gataggtttg tattcatcat gatggataca aacgttaaac gacagtttgt
    31921 atctatgatg gctaaagaac tttgtattgc agcaaaaagc cacgtagaca aaatgctaag
    31981 tggctgagca gtgaaaatac aaagtaaaag tatcaagcat tctacttttt caatttattt
    32041 tccgactttt caatccattt ggacattttg tctgaatgga ttttttgttt cccaaaatta
    32101 aggaggaaaa agaaatgaaa aaaaatataa tcatcggatt aggcgctgcc ctgctactag
    32161 ctttaggagg ttgcgcacaa aaagacaatt ccgcagaggc atcagatgga caaaaaacaa
    32221 ttggcgtatt gcaacttgta caacataact cgttagatgc tgcctataaa ggattcaaag
    32281 aaggattagc agaagaaggg tataaagaag gcgataatct aacaatcgat tatcaaaatg
    32341 cccaaaacaa tcaagacaac ctgaaaagta tgagtgagaa actcgtcaaa gaagatcctg
    32401 atttgctact tggaatcgcc actccagcag cacaatcttt attaaatgaa acaaccacta
    32461 tcccgatgac tgtcacagcg gtcacagact tggaacaagc ccatttagtc acatccaatg
    32521 aaaaacctgg cggcaatgtg actggcacga cagatatggt gccaatcgaa aaacaaatcg
    32581 gcttactgtt aaatatcgtg ccagacgcca aaacaatcgg catcatgtat aacaacggtg
    32641 aagcaaactc taagatccaa gctgatttgg cagaaaaaga attgaaaaaa gcgggcgtca
    32701 aagtcaaagt actgacagca aattccacaa atgatgtcca acaagtgacg aaaagtctag
    32761 ctaaagatgt agatggaatc tatattccta ctgataacac gttcgcaagt gcggcaagtg
    32821 ttgtcggtga agtcgcaaaa gaaacaaaaa cacctgtcgt tgctggcgca gttgatcaag
    32881 tcaaagacgg cggtctagca acagtaggaa tcgactacga aagcttgggc aaacaaacag
    32941 ggatcatggc agcaaaaatc ttagacggca agaatccaag tgaacttcct gtcgaaacag
    33001 cgaatgattt ggaactgtat gtcaataaag acatggccaa agcattaggc atcaatccag
    33061 acagcatcaa agaagctgaa taaaacacag gaggattctc atgacaaatt tgctctctct
    33121 tttcttatca tctgcatcgc aaggggtctt atgggcccta cttgcgattg gtgtatacgt
    33181 cactttccgt atcttggaca ttgccgactt gactgctgaa ggaagctttc ctttaggtgc
    33241 agggatcgcg gcagtaagta ttacaaatgg ctatcatcca ttgacagctt gtcttctagg
    33301 ctttttaggg agtgcggcag cagggcttgt ttccggactg cttcacacaa aattgaaaat
    33361 tcccgccctt cttgcaggga tcatcaccat gactggttta tattctgtca catcccgtgt
    33421 gatgggtgcg ccgaacatct ctttattggg tcagccaacg atctttcatt gggtcgagtc
    33481 attcggcata acaaaagaca acgctgtact gatcgtcggt ctgctttttg ctttgatcgt
    33541 tgtatgttta cttgttttgt tcttacgtac agaaacagga cttgctattc gtgcaactgg
    33601 cgataatctg gcaatgagcg aagcaaacgg gatcaacaca gataatatga agatcatcgg
    33661 ttatatgatt tctaatggat gcattgctct ttctggctcc ttgcttgcgc aaaacaacgg
    33721 ctttgctgat ttaaattctg gtattggaac gatcgtaatt ggacttgctt ctattatcat
    33781 cgcagaagtt ttgttacgta accagccact atttctccgt ctcttgactg tcgttttagg
    33841 tgcggtcatt tatcgtttta ttttagcgtt agtcttcgaa ctgaatgttg aaccaagtga
    33901 ttcgaaactt gcttctgctt tcgtgctagt gatctgtctt tctttcccgc agatccagca
    33961 aaaattccat ttacctcaaa aaaagaaagg cggtagtgtc aaatgaatga cgtcttaaca
    34021 ttggaaaatc tccatcatac ctttgaaaaa ggaacgatca acgaaaatca tgtcctgaaa
    34081 ggcattaatc tttccttaga tcccggcgac ttcgtgacga tcatcggtgg aaatggggct
    34141 ggtaaatcta ctttgctgaa cagcatcgcc ggtacatttt ctgtcgatca gggtcaaatt
    34201 ttattgaatg gaaaaaatat cacgaaaaaa tctgttgtcg aacgttcgaa atccatcagt
    34261 cgcgtattcc aagatcctaa actagggaca gccgttcgtt taacggtaga agaaaatctt
    34321 gctcttgcta tgaaacgagg aaaaaaacgc ggcttcttcc gtggtgtcaa accacaagac
    34381 cgaacatttt tcaaagacca gctggttcgg ctaaatttgg ggttggaaaa tcgtttatcc
    34441 tcagaaatcg gtttgctgtc tggaggacaa cgtcaagcta ttacgttatt gatggccaca
    34501 ttacagcgtc cagaactgat cttattagat gaacacactg cagcgcttga ccctgctact
    34561 tccaaaacgg tgatggaatt gacagaaaag ctgatcactg agcagaatct cactgctttt
    34621 atggtcactc atgacatgga agacgcgatc cgctatggga gtcgactgat catgctgcat
    34681 caaggaagga tcgtcgtaga tatccagcaa gaggaaaaac agcagctcac agtgccccaa
    34741 ttattagcgt tgttcaaaca aaacagcggc acggcattaa aagacgatca agtactttta
    34801 tcttcataat cagaaagagg atgggacaaa aaatgaacgc ccaccctctt cttttttctc
    34861 tttccttctt tcgtttttgc tttatgtatc aaccgttgtt tcttcgaaaa ctattttgtt
    34921 ctctccttct tcctgataga atggatggga aaggagcttg atgccatgac aacgaaagac
    34981 aaggtacttc aattattgaa aaagacacca gattttcttt ccggagaaaa gttggcacag
    35041 caactggaag tttcccggac aagtatttgg aaagccatca aagaattgga aaaggcaggc
    35101 tatcgttttg agcacgggcc tacagggtat cgttacctgc cctctgacgt actagatgca
    35161 aaagaaatcc agcaagagct acggtcgttt attcctgatt tgaaagtaca aacgatgatg
    35221 acttctgaat ctacgatgaa agatgccaaa ctggcagcag ctcaaggaga ttctgtttcg
    35281 aagttatttg ttgctgatac acaagaacaa gctcgtggac gttttggacg gccttttttc
    35341 gctgaacctg gacgaggaat ctacatgagt ctcttgctcc atccagacaa acggtttgat
    35401 gaattgcctc aatatacgat catcgcagcc agtgcctgtg tgaaagccat tgaatctgta
    35461 accggtcgtt ctgcttcgat caaatgggtc aatgatatct acatggatgg aaaaaaagtc
    35521 tgtgggattt tatctgaagc agtcagtgat atggaaagcg gcaggatcag tcatatcatc
    35581 attgggatcg ggcttaattt ttctgttcct caaaatcatt ttccagctga tctccaagaa
    35641 aaagccatct ctgtctttcc cgacggacaa gctagtgtca caaggaatca gctaatcagc
    35701 aaaatctggc aagaattgtt cacttatctt tctcacccag aaaaagcgtt ggacttctat
    35761 aaagaaaaat cattcgtatt gggaaaaacc gtgtcgttca atcaaaaagg aacgacttat
    35821 gtcggtcttg caaaagaaat cggtgatcat ggcgaactga tcgtccaaac aaatgaacag
    35881 aagatgagtt tgtcttctgg cgaaatcagt ctcacatcta tccgtacgca ataattatca
    35941 gatttcacaa aaggacacct gatctcatac agtgtccttt tttctgaatt ctcttcaaaa
    36001 gactctcctt attctatcag ctgacagttt ctctatcctc tagaaaaagg tattctaaaa
    36061 atatctataa agcatggtac actttcttta aatgaatcaa tgcaaaaaac aagagagtca
    36121 tcagtttaca cgatcaaaag agatagcagg ccgcttcctt tttcaatctt atagatagac
    36181 catgggtaac gataaaaaca aaaaagaact tgcgacttat tttgccgtaa gttctttttt
    36241 agctagtgcc ttaatctctt aatcccaaca aacgtctcgc atagatcacc tgaccagagt
    36301 gcatagcagc atcatcaata atagaaacga gacgcattcc tcgtgtgact ggtggtgtcc
    36361 agttctcgtc aattacttca tctagctcgg aaggttccag ccttcttaag taagaaatag
    36421 caaaatcagc agctcctcgc aagtatccta gcagatcttc tatttgatta gcttggatct
    36481 gctttgcttg ttccagacta tgcttccaat cttgttcgtt atctgctatc gtcatcggaa
    36541 accggctttc ccagtcttga ctatgccaaa ttggagaagt tcctgctaaa tcagcaatct
    36601 ggaaatctaa ttctcgagcg gtatgccaag ccagccaagt cattgatttg atctgcgggg
    36661 ctctatcttc cactggaaaa cgattggcct cctcaataga gacgccttca aacaaacgtt
    36721 caaaccgatc gtatgcccga tccacactct cgcatagcat atctaaataa tccatttatt
    36781 ttcctccttt ttatttatcc tacttacttt ttcctaattc taggatacct acttatatgt
    36841 tactacacac ccttattttt tacactttaa cagtcaccat catcaatagt ttggagattg
    36901 aaagaaaaag atagtgtcga actatcaatt gaacaagaag caacaatatg aacgtttcat
    36961 taatattctt taaataaaca atgatttttc aaacgaacag tttaagacta ggagaaaaag
    37021 agtataatag gaaaatgttt gaaaggaaag gaaggggaaa aatgaaaaaa agggcaagtt
    37081 tactagtcct agttgctttg ttgttcaata tcttttcgta tggtgtggcc gtttcagcgg
    37141 aaacatacat tcctaaagac cctgggaata tttataatga tctaactggt aactatggct
    37201 tgttaggaat tgctagtcaa ttccacgtat ttgctaaaaa taagacaact gtgaatgcac
    37261 atacagacgg aaatatagca acacatgaac ttgatgcaaa aaataatttt ggtacagagc
    37321 ttcatgaagg tttattgaac caagaaataa attatataca aaaaactgat tctttcgcta
    37381 attcttcagg catacctaca ggtagcacaa gaatgaataa atttgtcgtt ggcagtaacg
    37441 tggatgtagc acttcaagat ggtcatccta cagtcaatgg atccaggctt gatcacttaa
    37501 ctccagatga tttttataaa gatcgtgctg ggcatgaata tattgatttc gagcaggaat
    37561 ttgctaaatt gaatgtagca gcaaatgatc ttgcaacgat cactccagct aaaacatata
    37621 ctgctgcaga ttttccagac atgaacaatc ggacaatcga tttaactgat ttatcagata
    37681 ccgggttttt attggtaaat atcgatgcag aagtgttaac gatgaatacg ccacttcaaa
    37741 tcattaatcc aaatgatcaa gtagttgtat ttaatgtcat caacagttct tctgcattga
    37801 acgtacagtc accaatcaaa tacaatgatc gttcaaatca tgaaacagaa gatttttcgg
    37861 atgcgaatat ctcttggaat tttggaaatg agatgactga tttgacaatc agtgctcctt
    37921 ttcaaggaac aatccttgcg cctaatgcta ctatccgcat tactcaaaac caagacggaa
    37981 cgattatagg aacaaatgtg attttagatg cagctaccaa tcgttgggat cctaacgaaa
    38041 tatttatcag cgacaatggt acagatacga cagacacaag cgacagtaca gatacatcta
    38101 ccacaagtga tagctcagat tcatcaactt caagcgacag tacagatact acctctacca
    38161 caagtgatag cacggatac
//
LOCUS       DAZKKZ010000023        36949 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.023, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000023 DAZKKZ010000000
VERSION     DAZKKZ010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 36949)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36949)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36949
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.023"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            45..1412
                     /gene="nhaC"
                     /locus_tag="ACG8LA_001243"
     CDS             45..1412
                     /gene="nhaC"
                     /locus_tag="ACG8LA_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA];
                     GO_function: GO:0015385 - sodium:proton antiporter
                     activity [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HFQ0203549.1"
                     /translation="MNKNISLKESIAVLIVLLALLGVLIIGFQLSPHIPILAAFMCLL
                     FYGRFKKFTWDEIHDGIIKGITPGIIPILIFLLIGVLVASWILSGTIPTIMVYGFKLV
                     SVRFFLPTAFLVCAIVGVTVGSSFTTISTIGIAFLGIGHLLGFNDAMTTGAVVSGAFL
                     GNNCSPLSDTTNLAAGIGGVNLFEHIAGMRYTDFPAFVLSLIFYTILGHNSHSADLAS
                     INEMIQNMKASFWISPWTLIPLVILFGGAIKKIPAIPTLLAGSTAALVLSFIHEKSLT
                     VGKAADILMNGYVANTPDPKLDELLSRGGIMSMLGSASLILLALALGGLLIKYLIVDT
                     IVQELKEKMDRPSRLVGFTALSCIGINLIVGEQYLSIILPGETFKRSFDDVGLSKTYL
                     TRTLADSGATVNSLVPWGVSGTFIMGTMKVSALHYLPFAFFSILAPVFTILGGFLLNR
                     RRVKN"
     gene            complement(1693..2712)
                     /locus_tag="ACG8LA_001244"
     CDS             complement(1693..2712)
                     /locus_tag="ACG8LA_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFQ0203550.1"
                     /translation="MAITVKDVAKKAGVATSTVSRVINDHPSISETTKKKVRKIMDEL
                     GYVPNMTARNLGKRISSAIGVILPPLDSKERIGNPFYLEIMEAINEEARNYDMTTAIA
                     TAKNFELLLENVQRMHLQKQVDGFILVYSDSQDTVIDYLYQNHIPFTLIGQPYHHENE
                     IVYVDNDNQLLGKQATEFLIQNGHKNILFVTNTTHESLYFERYFGYQKAMMMAGLPAL
                     SSVVLEHPEDYLSFEKTLKENEATALVVIDDIFALRTMQLAQMYGYVIPETLSVISFN
                     NSIFSTLTHPYLTSIDIDISELGRVAMQKLRELIHEELSSGVRLVIPHRLIKRETVVP
                     LENPY"
     gene            complement(2734..3741)
                     /locus_tag="ACG8LA_001245"
     CDS             complement(2734..3741)
                     /locus_tag="ACG8LA_001245"
                     /EC_number="5.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase family protein"
                     /protein_id="HFQ0203551.1"
                     /translation="MDNPEISVVPVPETEIKKITLKNDYLEVVLLNYGARLHQIFAPD
                     KEGKSENVLLSYDRFEDVLTDKSFFGATVGPVAGRIRDASWGEHRLEKNCGSHHIHGG
                     TKGWSFQFWEVEVFKTPSSIGVVFYLKDEFSTYPGPITATITYRLTKNELEMTTSASS
                     LVETICNPTNHAYFNLSGNGTRDIYEHQLTVFLDGVLELDQEKLPTGNWTKKEKLPID
                     FRKSPTLQEILACYPDGLDDVFLLHHPRLSKTSLQLFEKHSGRQMTIATSNKSMVLFS
                     TTGFEADFSVNGKQMHSNYGLAIEPQEIPDIVHFPKFGSINLHPGQERISQTIYRFSA
                     Q"
     gene            complement(3734..4399)
                     /gene="pgmB"
                     /locus_tag="ACG8LA_001246"
     CDS             complement(3734..4399)
                     /gene="pgmB"
                     /locus_tag="ACG8LA_001246"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008801 - beta-phosphoglucomutase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HFQ0203552.1"
                     /translation="MFKGVLFDLDGVITDTAEFHYRAWRKLGQEIGITIDHTFNEQLK
                     GVSREDSLSLLLAYGGKEHSFSKEEFAELAKRKNDYYLEMIQTIEPKDVFPGVVPLLD
                     SLKEEKIKIALASASKNGPFLLEKMGLTPYFDAIADPAEATNGKPAPDIFLLAAKAVG
                     LKAEECIGIEDAQAGIQAILSSGAQPIGVGRAEDLGEEIPLVPDTTFLTIDYLKEKWH
                     DHG"
     gene            complement(4392..6686)
                     /locus_tag="ACG8LA_001247"
     CDS             complement(4392..6686)
                     /locus_tag="ACG8LA_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HFQ0203553.1"
                     /translation="MKQIKRLFAIDPWKISTTQLDKKNLRLQESLTSIGNGYMGMRGN
                     FEETYSGDHHQGTYLAGVWYPDKTRVGWWKNGYPEYFGKVINALNFIAIDISINDQLI
                     DLASLEPEDFYWELDMKNGVLSRTFTITTSTNKVRISFERFLSIVKKESAYIYLTIEM
                     LEGSGTVKLVSKLDGNVQNEDSNYDEHFWNEIDRGTIEEIGYLTTKTIPNNFGIEQFT
                     VTAAMRHFVNGKSVIPDYHEDTLALHGCLSAELSQGETWSVEKEIIVLTSRDIPEAQQ
                     AEKAVSELTNQTNNYIQAKEEQTAAWAERWKLADVVIEGDEEAQQGIRFNLFQLFSTY
                     YGEDERLNIGPKGFTGEKYGGATYWDTEAYAVPLYLALAKPEVTKNLLKYRHNQLPQA
                     IHNAQQQGLKGALYPMVTFTGVECHNEWEITFEEIHRNGAIAYAIYNYTNYTGDTEYL
                     KNEGLEVLAEIARFWADRVHFSKRANKYMIHGVTGPNEYENNINNNWYTNTIAAWVLR
                     YTRENYLTYQKEAAITISEEELAKWKDIAENMYFPVDEELGIFVQHDTFLDKDLMPVS
                     DIPTSDLPLNQHWSWDKILRSCFIKQADVLQGIYFFNDTFTKEEKQKNFDFYEPMTVH
                     ESSLSPSIHSILAAELGMESKAVEMYQRTARLDLDNYNNDTEDGLHITSMTGSWLSIV
                     QGFAQMKTAHDQLRFAPFLPKTWKAYSFHINYRGRLLFISVTDEQVTFELLEGSPLEI
                     YVYEQSYSLADRLEITLRKEEANV"
     gene            6946..9111
                     /locus_tag="ACG8LA_001248"
     CDS             6946..9111
                     /locus_tag="ACG8LA_001248"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015144 - carbohydrate transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIBC"
                     /protein_id="HFQ0203554.1"
                     /translation="MKKIFSFEFWQKFGKALMVVVAVMPAAGLMISIGKSIPLINPDW
                     TPLVTTGGVIENIGWAIIGNLHILFALAIGGSWAKERAGGAFAAGISFILINRITGAI
                     FGVTSDMLANEDAFTHTLFGTKIMVKGFFTSVLEAPALNMGVFVGIIAGFVGAMAYNK
                     YYNYRKLPDALSFFNGKRFVPFVVILWSTIVALILAVVWPNVQAGINNFGLWIAESQE
                     SAPILAPFLFGTLERLLLPFGLHHMLTIPINYTQLGGSYEILSGAQAGTQVFGQDPLW
                     LAWATDLVNLKGAGDMSQYEFVLHNWTPARFKVGQMIGSSGILMGMAFAMYRNVDPDK
                     KARYKSMYFSAALAVFLTGVTEPLEFMFMFAAVPLYVIYSVIQGAAFAMADILPLRVH
                     SFGNIELLTRTPLAIKAGLGGDLINFVLCVIAFGVVTYFLANFLIKKFNFATPGRNGN
                     YDNDSEETVVSNSGTGTADQQVVQIIHLLGGKENIKDVDACMTRLRVSVNDREKVGTE
                     EAWKRAGAMGLIVKDNGVQAVYGPKADVLKSDIEDLLQSGAEIPEPEMVSTGNGQAGS
                     KQYLGIEQELVSAASGEVIPLSEVKDPVFSQKMMGDGFAVIPTSREVVAPIAGKVTSI
                     FPSKHAIGLETKDGIEVLIHMGIDTVQMNQPAFEIAVKEGQEVGTGTKLAEMDLDVIQ
                     NEEKDPTIMIVFTNDKVEEVVIKQLGTVTAGKVIGSIKM"
     gene            9415..10248
                     /locus_tag="ACG8LA_001249"
     CDS             9415..10248
                     /locus_tag="ACG8LA_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HFQ0203555.1"
                     /translation="MKFMTLNTHSWLEPEPEKKLQELADKILLEDYEVIALQEINQLL
                     ESEEVEPAKLMKFCPVKNQVPIRKDNFAYRLVQLLKEHGKEYFWSWEMSHIGYDKYEE
                     GNALLTKKTLESQVLTVSQFQKKEDYQTRKILIGKTKIDDQDIFVSSCHFSWWTDKKS
                     GFYFEWKNLENYFLETRVPLFFLGDFNNPVDSQGYYTVRESCLLLQDSYVVANEKGKA
                     ATVEKKIDGWEQNTEKLRIDFIFVPEGMQVKKYQRIFDGIDSPIISDHYGVEIELDVN
                     E"
     gene            complement(10350..12050)
                     /locus_tag="ACG8LA_001250"
     CDS             complement(10350..12050)
                     /locus_tag="ACG8LA_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0203556.1"
                     /translation="MMNLSKVCKGVRQLKKYGPFLAIFFIALAFLMPHLFTHKLILGA
                     DAPFHYNRFYDAAQQIKYGDFHYFPSLYGFQQSGRIVNAVYGPFFAYLQGLIVLLAGS
                     WFHYQILSNFILYLISGFSMLILLRYVNVRNWVSVPVAVLFMSTYSIQYWSINQGFTS
                     WGTCFYPLCMIPIADFVLHKKFPVIKVAVSVGLMTQIHLLSSIMLALMYIPFYLYYFF
                     NQTEKGKALLQLIKSVLLYFVLTANIWAGLAIVYSGNKILPPFVNREMSQKAIDLDGS
                     YWLHYPKAFPILILSGFLLFIFFQQKNTLFQKIVLYTSLVFFFLSTSLIPWTTLIEKN
                     VPFISLIQFPFRFFVPFTLLLLLYLALSLNQWSEQKWFRLLSIFGILIFSAQTIQNLY
                     QHLEKWENETFVSRHTYLFDTPEEARKTFFSKDMSTSLFVFQKTTPDYLPIYKETKDN
                     KYDRYNEEILENETTFIKTHPGGLLTIKWKNTGDKTVHIPVIVYDRTVLQQNGKTLTD
                     YEVTDIGTPIVKQQKGINELTLHYQTPIYFYFILSLTLIGWFTLLCLFIYHRYKLLRA
                     "
     gene            12557..13717
                     /locus_tag="ACG8LA_001251"
     CDS             12557..13717
                     /locus_tag="ACG8LA_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HFQ0203557.1"
                     /translation="MKQSKQKQSRRLLFRLFLLICIVVGLLIALYPFYVDSLNSFIDQ
                     KRIEQVQKRTAAEIEVQRKKMEEKNQRLTDQGFNPGTDPFNEKNRNESTTSSQLEEWL
                     IGSINIPKIQLNISLYDRLNGRILENGAGVLQGTSFPLGGNSTHSVISAHSGLPNRRL
                     FTELDRLENGDTFILTVLGEKLAYQVKNIQVVLPDDTSVLTISEGEDLVTLLTCTPYM
                     INTHRLLVTGHRIPYNESVKKEEGKGNQERTMRQWFILAGTIIAVVILLVFIGRLIYQ
                     YRLSKKVLDFSFIISDSSGKPVNGSSFILKHKKKTLTRNGVPFSVQSDHHGKVKLDQL
                     PGGTYRIVSADDPKVAVSFGIRKVKQEKIYFFEGRKLVKELQKNGFYFKINE"
     gene            13733..14176
                     /locus_tag="ACG8LA_001252"
     CDS             13733..14176
                     /locus_tag="ACG8LA_001252"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFQ0203558.1"
                     /translation="MIRTTTKLSAKELESVLSIWLHANLDSHEFIPSTYWENQVESVR
                     KALPDAVIYLAEIDQEIIGFAGVIDQFIAGIFVKREYRQQRIGTQLMKKIKETNKTLT
                     LTVYQKNQSAIHFYLSQGFTIQTQQKDEAVNEEELVMKWNQNADF"
     gene            complement(14659..15189)
                     /locus_tag="ACG8LA_001253"
     CDS             complement(14659..15189)
                     /locus_tag="ACG8LA_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenolic acid decarboxylase"
                     /protein_id="HFQ0203559.1"
                     /translation="MKEFKELEDFIGTHFIYTYDNGWEYEWYAKNDHTVDYRIHGGMV
                     KGRWVKDQEADIVKLTDGVFKITWTEPTGTDVALDFMPNEKKLHGMIFFPKWVEEHPE
                     ITVTFQNEHIAEMEAAREKYETYPKLLVPEFATITYMGDAGIDNEDVISEEPYDGMPD
                     DIRSGKYFDENYKRVK"
     gene            15294..15845
                     /locus_tag="ACG8LA_001254"
     CDS             15294..15845
                     /locus_tag="ACG8LA_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HFQ0203560.1"
                     /translation="MARKNTLRYILLGLLSKKKMTGYELNQSFKNEIGEFWQAKHSQI
                     YPELAKMEEQGIIQHQVEITGEKLEKKVYELTEEGKEQLAEWIHTPTNELPVNRDEFV
                     LKLYFVKDVNDPALVEIIQQQRDLHEEKRLHLLERKKTIFPTEKEKHENYGHYLILAH
                     AINRETEYANWLTDVLEESNRKK"
     gene            complement(15998..16471)
                     /locus_tag="ACG8LA_001255"
     CDS             complement(15998..16471)
                     /locus_tag="ACG8LA_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HFQ0203561.1"
                     /translation="MVGASLKRLLENDQLVVGISELSDIVGVSPRQLRYWEQKGFIRS
                     IEADANCPRKYRLPTVIKVELIKKYLDDGFTLSKAAEKAEIRQKKMHHVRKVFSKAIK
                     DIELIDERYTILQIGNFKEENAKMYIIHDNETDELTYKLLPVDEKADYEQLLKEL"
     gene            16609..18081
                     /locus_tag="ACG8LA_001256"
     CDS             16609..18081
                     /locus_tag="ACG8LA_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008269079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MDR family MFS transporter"
                     /protein_id="HFQ0203562.1"
                     /translation="MSNNQPVDIYGKPYNRTLLVVVLLIGTFCTVLNQTLLTTAFPTL
                     MKAFDISASDVQWLTTGFLLVNGIMIPITAWLINKFSSRNLYLSAMTIFLIGTITCFT
                     APNFSTLLIGRLIQACGVGVSMPLLQNIMLSIFPPEKRGSAMGMSGIVIGLAPALGPT
                     LSGYIIDNYHWRDLFGMVLPIVVLVLVLAFFLMKSVIPLSNPSIDILSAILSTIGFGS
                     LLYGFSSVGDDGWGSLKVIGFLVVGVIFIALFSWRQLHLEHPFLELRVFKSSTFTIAA
                     VLAGVTNMAMVGAEMVVPLYIQNIRGESAFHSGLMLLPGALIMGAMMPVTGAIFDKYG
                     AKRLAITGMFILTAATAPFAFLTKTTPVLYIVILYAIRMFGISMVMMPVTTSGMNALP
                     NNLISHGTAVNNTFRQIASSIGTAILISVLTNVTKANIPSKSVLDNTPLAYKDQAINA
                     TLSGYHAAFIVAIIFGILGFIIAFLLKKKEPVLMKAGDNA"
     gene            18078..18788
                     /locus_tag="ACG8LA_001257"
     CDS             18078..18788
                     /locus_tag="ACG8LA_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4811 domain-containing protein"
                     /protein_id="HFQ0203563.1"
                     /translation="MIIGVLIVSLLAFALTNVFAKKTWQTFLSLIFGLIFVASLSLIV
                     ANLSNHFGMEKVTETKTEKIVSSADSQGADMLLYKALGNGKEKVYLYRTNEKQEKPKA
                     TGTDNETNKVEKTDGDAEKVTKTTYWEYKNDMYKFWFNIADNNHEYDSRVNTFKIPET
                     WVELSTDQAAKLAELVKKQQSTMESEAKAYVQDGMVKAMTENPKMSKAEQEQRTKALA
                     AEFQQQAFAKLVKEAKGE"
     gene            19140..19424
                     /locus_tag="ACG8LA_001258"
     CDS             19140..19424
                     /locus_tag="ACG8LA_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1905 domain-containing protein"
                     /protein_id="HFQ0203564.1"
                     /translation="MREIYSFESKIYASEVGKGGAYIIFPYDIRKEFGAGRVKVQATF
                     DNVPYEGSIVNMGVKNPDGSVCYILGLRKDIRKNIGKEIGDIVAVTVKQK"
     gene            complement(19741..20124)
                     /locus_tag="ACG8LA_001259"
     CDS             complement(19741..20124)
                     /locus_tag="ACG8LA_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid decarboxylase"
                     /protein_id="HFQ0203565.1"
                     /translation="MEKETIVEVTKLGFTIQAAVKVIGKDLLITLTGGDTPHIGTVTT
                     FSRDTEMQTVRFPSHDGRFHKDDVLAEKIAVIIKTAVPGSCTITSGIHVDHISNAQIN
                     ASFPMSEELGYKILDWLEKIDFHIK"
     gene            complement(20126..20710)
                     /locus_tag="ACG8LA_001260"
     CDS             complement(20126..20710)
                     /locus_tag="ACG8LA_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiX family flavin prenyltransferase"
                     /protein_id="HFQ0203566.1"
                     /translation="MEQLAQRKKKIVIGVSGASGTIYAINLVKKLKEYPMIETHGIIS
                     PWAKQNLKLESDLSLTEFESLFDYHYSNKDLGAAVASGSFLTDGMIIVPASMKTVAGI
                     SVGLGDNLIARAADVTMKEQRKLVIVPRETPLNAIHLENLTKLARLGVQIIPPIPAFY
                     NQPQTIQDLVNHHTMKLLDQFEIVNEHSKRWQGD"
     gene            complement(20757..22232)
                     /locus_tag="ACG8LA_001261"
     CDS             complement(20757..22232)
                     /locus_tag="ACG8LA_001261"
                     /EC_number="4.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UbiD family decarboxylase"
                     /protein_id="HFQ0203567.1"
                     /translation="MTDQPYDLRKVIEELKTLPGQYHETDIEIDPEAELSGVYRYIGA
                     GGTVKRPTQEGPAMTFNNIKGFPGTRVNIGTMASRKRVGEILHHDYRTLGRFLKDAVE
                     NPIKPVKVDKADAPAQEVVHLATDADFDIRNILPAPTNTPEDAGPYITMGVVLGSDPE
                     KTMSDVTIHRMVLEDKDTIGMYIMPGGRHIGHFQKQFEALNKPMPITINIGLDPAIAI
                     GTTFEPPTTPLGYNELWCAGALRNEPIQIVDGIAVDEVGIARAEFIIEAEIMPNETMQ
                     EDINTNSGKAMPEFPGYTGDANPAVQVVKVKAVTHRKDNPIMQTTIGPSEEHVSMAGI
                     PTEASILALVDKAIPGKVVNVYNPPAGGGKLMTIMQIRKENEADEGIQRQAAILALSA
                     FKELKTVILVDEDVDIFDMNDVVWTFNTRFQGDKDIIVIPGMRNHPLDPSELPEYNPG
                     SIRFRGISAKTIFDGTVPFDMKEHFVRAKFQEVEDWEKYLK"
     gene            22413..22724
                     /locus_tag="ACG8LA_001262"
     CDS             22413..22724
                     /locus_tag="ACG8LA_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0203568.1"
                     /translation="MKKMEESFPKAVKVENIANILKVTFENGEVKYVKSHWTEEITDA
                     LQFGKKGRGKRKNLLALSRNMWIGTEVTIEADGTVFINGKDRYTPEELWYKGKKSIPE
                     L"
     gene            complement(22839..25175)
                     /locus_tag="ACG8LA_001263"
     CDS             complement(22839..25175)
                     /locus_tag="ACG8LA_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein/permease"
                     /protein_id="HFQ0203569.1"
                     /translation="MLQLKDIKKYYKVGETTTKALDGVSVAFRQKEFVAILGPSGSGK
                     TTMLNVIGGLDNYDSGDMVINGKSTKDFKDSDWDAYRNNSIGFIFQSYNLIGHLGIIE
                     NVELGMTLSGVSKDEKRKRAEDALHRVGLTNHMHKKPNQLSGGQMQRVAIARALANDP
                     DILLCDEPTGALDTETSIQIMELIQELSKEKLVIMVTHNPELAHQYADRIIEFSDGKI
                     LTDSHPHIERPKDDQFNLRRTKMSFWTALKLSFNNIRTKKGRTFLTSFASSIGIIGIA
                     IVLSLSSGFQKQIDNTQAETMAKFPITISKVTTNQTRDDAGLGASKADYPDSKTITAK
                     VSEEDKAQHTNKIDQTYVDYVTDIDPNLSNNIGFTRTTGINLLRDVNGKVQPVSFSNQ
                     NPDTESLSLSSTMSAMTGVGVSSFPTQLDTSKENFLKDNYSLLAGSYPASATDVVLIV
                     DGNNNTNINALKNLGFDVKEDEKLDFDDIVGTTFKLVNNNTYYTKLPTGNFIPNTDYD
                     AMYQNASDELKISGILRVKSSSTMNLLSPGIAYSDQLTTQIVNENKESEIVKAQRDSG
                     VNVLTTEKVDENAKQTLLSYLGGDSLPSSIMIYPNNFEDKEKILDYLDDYNKGKSDED
                     KIIYTDLAGTMTELTGGLMDAITYVLIAFAGISLVTSMIMISIITYTSVIERTKEIGV
                     LKALGARKKDITRVFDAETCILGISSGILGVFIAWLATFPINSILYNMTDLKNVAQLN
                     PVHAIILVIVSTILTMLGGHLPARMAAKKDAAIALRAE"
     gene            25317..25985
                     /locus_tag="ACG8LA_001264"
     CDS             25317..25985
                     /locus_tag="ACG8LA_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFQ0203570.1"
                     /translation="MNRILVVEDDPQLQLLYRSVLERAGFSVITALNGEDALKKLEAT
                     RIELIITDIMMPKMDGYDLLDSLRSTRFDTPVLMITAKADFEDKKRGFKLGADDYMTK
                     PIDVNEMILRVEALLRRSKINYSSSLIIGQTKLELDAYTVLQDQHSLILPQKEFLLLY
                     KLLSYPNKIFTRQQLMDDIWGLDTNTEERTIDVHIKRLRTRFEKTEDFQIITVRGLGY
                     KAVI"
     gene            25988..27031
                     /locus_tag="ACG8LA_001265"
     CDS             25988..27031
                     /locus_tag="ACG8LA_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFQ0203571.1"
                     /translation="MKKKLFSQLWIYFASIVFISILVTLLCFLGFIFLLSRHSISPAE
                     SAGKPTLYPLFVFAGFSMVVGTGISIFVGRRILHPISALGTNMSLVATGDFSIRMDEQ
                     QKVAEVQQLYKDFNVMVQELNSIETLRNDFVSSVSHEFKTPLATIQGYVQLLQAPNLS
                     DEERQIFLYRIIESITQLSQLTENILKLNKLENQRIQLEKKEYRLDEQIREVIVFFQP
                     KWEKEQLELDIELAAVNYTGNEEFLYQVWLNIMDNAIKYNQINGQIHIKLFETATEIV
                     LEVTDSGVGMNEETRDRMFEKFYQGDTSRQISGNGLGLSLVKKILELHDGRIDYSSIE
                     GVGTTAMIRLSKQ"
     gene            complement(27268..28149)
                     /locus_tag="ACG8LA_001266"
     CDS             complement(27268..28149)
                     /locus_tag="ACG8LA_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFQ0203572.1"
                     /translation="MDIHKFEVFLDLAETMNFTKTADRQFTTQGNISKQILSLETELD
                     VKLFERAHRKIELTEAGSLLLPYVKNVVEQYHAMQEVLETYTKDNNLSLNILTIPTMI
                     NYKGFSKITEFLKRHPEFTVQLKEVESVELTYNDANEHSDTIHFARSFQAPPSSIEWL
                     PTETDDFVAVLPKNHPLASKKKLDLSELKKENFLLLGPTTNLYQPVLDLCREAGFEPK
                     ISYKGARIDLIINMIANDMGIAIVMEKTVKNLLKENTVILPISPTTESYLAFTRKVGE
                     HSLASDTFWEYLNQEEN"
     gene            28308..29036
                     /locus_tag="ACG8LA_001267"
     CDS             28308..29036
                     /locus_tag="ACG8LA_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF554 domain-containing protein"
                     /protein_id="HFQ0203573.1"
                     /translation="MPTGVLINVGSVLFGGLIGGLVGNKLSEHFKAQLTMVFGVCSMG
                     MGIYSIAPMKNMPAVIFALVIGTAIGLIVHLGNGINKGAALMQVPISKIFPSEKLGMT
                     HDEFISTLVTVIVLFCASGTGIYGSLDSGMTGDSTILISKSVLDFFTAAIFACNLGYV
                     VSVIAIPQFIIFYILFLLAKFIYPLTTPDMILDFKACGGFLMVATGFRMINVKMFPVA
                     DMIPAMIVIMPLSWMWTNWIMPLL"
     gene            29192..29509
                     /locus_tag="ACG8LA_001268"
     CDS             29192..29509
                     /locus_tag="ACG8LA_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HFQ0203574.1"
                     /translation="MHIQIPTVLLDGTVLAALSKEDMYGYALTKIVQESLSVSESTLY
                     PVLRRLKKEGYLETYDEPFEGRNRRYYSLTPMGSRHLEEIIDEWIVFRDSLDRLLEES
                     TNE"
     gene            29502..30110
                     /locus_tag="ACG8LA_001269"
     CDS             29502..30110
                     /locus_tag="ACG8LA_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HFQ0203575.1"
                     /translation="MNEYLNEVVDHLQEIPEDDRFDLIQYYEEYFLDSGKTLDQIIDE
                     YGTPKQFALKLKISYFSEEEQAENELVKNPKRQIRLIWLIIIGLFASPVLIPLALGFI
                     LVIGGLLVALLALIFSIYVLCISILGVGLFMIISGISVFGQSILSGLFFIGVGLFATG
                     SAVFISPLLLKGTKGLFYVMMNFVKWMGRRFITKRDLHSAGV"
     gene            30165..30956
                     /locus_tag="ACG8LA_001270"
     CDS             30165..30956
                     /locus_tag="ACG8LA_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat-containing
                     protein"
                     /protein_id="HFQ0203576.1"
                     /translation="MLTGGLLAGATYTLGAQKSLTWDNGPRLIDMVTETKKIKDANKI
                     VIHAENQTVSVIRGLDFEIKTTYDKTEKPEIKEKNGVLTVNAVKKSTGAIISLEDTSA
                     QITIVVPADHELSELTIEGNNSAIDINEVSIKKVNTKTHDGWVSFNEFTGGTITAKDE
                     LGSLRLDEANVDNLIVTGENSNFHLEDSLISKEGKVILNGGNLSLHEMENSGYTIQTS
                     GESYIEKDYQPITNTLLEQGQKKLKITAKDTSINITTDQEDNETD"
     gene            31094..31582
                     /locus_tag="ACG8LA_001271"
     CDS             31094..31582
                     /locus_tag="ACG8LA_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5348 domain-containing protein"
                     /protein_id="HFQ0203577.1"
                     /translation="MKVEEGQREKLKTEMERLHTYITQLSQTFYDPDKEKVMVNYPNN
                     SEGRQLEQVYHEVFKHLLTVKKELDYYSLPIIDTGILKYDGKKERFIFKSVREDLPLS
                     AGMDLEVLVEDYFTEEKHWVRTKLDYLPQAAGGTQASGWYITEDKELELEGVMARIRK
                     KN"
     gene            31633..32505
                     /locus_tag="ACG8LA_001272"
     CDS             31633..32505
                     /locus_tag="ACG8LA_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HFQ0203578.1"
                     /translation="MREKRAFYINGYAGIVGLVVLALVGLFFFYLGMWQAKVWALFLS
                     IFLWLITLLLLSSATVVSPNQAKVILFFGQYLGTIRENGFFLTIPLAQKMTVSLKVRN
                     FNSSVLKVNDLDGNPIEISAVVVFKVVDTAKALFDVAYYQDFVEIQSETAIRHIASQY
                     PYDTFNENDLTLRGNTTAVSDELQKELQERLAVAGVEVIETRLNHLAYATEIASAMLQ
                     RQQAKAILSARQTIVEGAVTITQMALEQIEDGQEINFTDDRKVQLINNLLVSIITDKG
                     TQPVINTGDMKDRK"
     gene            32681..33043
                     /locus_tag="ACG8LA_001273"
     CDS             32681..33043
                     /locus_tag="ACG8LA_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HFQ0203579.1"
                     /translation="MKKLLIGLLVFIVVVLAGVKIADYVVMGGEEYYVQITTDGTKTV
                     SKSDSGQETVNYRYILPGYTKEGKEKELDFKGQLTRPLRKGAYLKITWNKNKGVTSYE
                     EVEKKDVPKTALEKLIKG"
     gene            33052..33804
                     /locus_tag="ACG8LA_001274"
     CDS             33052..33804
                     /locus_tag="ACG8LA_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0203580.1"
                     /translation="MNKIVEVQNVTKVYGKNNEKKTQALSGISFDVEKGEFIGIMGAS
                     GSGKSTLLNILSTLDKPTDGHIRINQKDVTTLKGNQLADFRANEIGFIFQDFNLLESL
                     TAQENIAVPLSLQGVRPKEIKQRVQKIAERLSISHILESYPSEISGGQKQRVAAARAL
                     ITQPTILLGDEPTGALDSKSARDLLDTMDELNTKDHVSILLVTHDPFSASYCQRILFI
                     KDGGIHQEVKRGDQSRDSFYREILSILGNLEQ"
     gene            33818..35620
                     /locus_tag="ACG8LA_001275"
     CDS             33818..35620
                     /locus_tag="ACG8LA_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFQ0203581.1"
                     /translation="MLWKLSLTGIKSRLRDYLVLFSGLVMASAIFYMFESMASNEAFL
                     KSNTIVAATVIIFRFGSVLLGIITFVYILYANSFLMTMRQKDYAMFMMLGAKGRKIAQ
                     MIFSETFLVGIAATLVGSAVGVGLTSIVHRLLVDQLDLNISHFTPFSIHGLLITVLFF
                     AVLFLLAAVVNAFSIVKKPILALIRADQTPTRIKQHKFLFFLEVVLGIAFLGCGYYMM
                     KHVGTYQVFGIGVALVTIVLGTYFIFHSVIIFFLSLLKKSEQISLKKLNNFTLSQLNF
                     RIREYTQMLSMVAMLFALALGALTVGLGFKNEIADLTENNSGYDLVMNNPRAEDQQKI
                     KELSPTLSASYTQKEDAGTIYYNASEFAAQPLIMIKHEDGTPPKITKEKVPAKKMNEL
                     TVQEELRSYELPEQQEKEIKVVSQSEFDQLNLPQSTLQLVQVKDFQANLKPIETLVAQ
                     NKMNNPSLQKVEYSNQKYEMYEVYNGLFSGFEFMGFFLGLAFLTMLASCLMFKILSGS
                     KSDIARYEMLEKIGTRRGLLKQSIRREVGVLFLAPGILGVVHVLFGLQMFGLFMQNPY
                     KDIWVPFTIFFVLYFIYYVLTTWLYTGIVLKKRL"
     gene            35897..36937
                     /locus_tag="ACG8LA_001276"
     CDS             35897..36937
                     /locus_tag="ACG8LA_001276"
                     /EC_number="5.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase family protein"
                     /protein_id="HFQ0203582.1"
                     /translation="MEINEQNFGENYHLITITNQNGTSLSVSDLGARVVHFQTIIDNE
                     KRELILGFDEAKEYLEKDPYIGASIGRMAGRITNGTFKLDDETFEVKTDPDTGHCLHG
                     GAPSFEAKQWHYTVINGENEASVIFYQTSPDMENGFPGTLDVEVRYTLTNDDTWRVTV
                     QGISDRKTVFNPTNHVYFNLTGDPAQSIDEHILWLNSRLFATLNKDTTPTGEVVSVSG
                     TAFDFQRPKKLGEVFASDFRQSMIVGGIDHPFLLKKQSGLLNAAELTSPDEKVSIQVK
                     TDASGIVIFTANFGEDGPEMRGNKLVNHGGITFETQELPGAERLESFGDVTLEPNQVR
                     EFVTEYKINIKK"
BASE COUNT        11456 a         6547 c         7633 g        11313 t
ORIGIN      
        1 ttttttcatg gcagggcctt ttcatttgaa ataggagatc gacgatgaat aaaaatattt
       61 ctttaaaaga aagtatcgct gtattgatcg tgttgttggc actcctagga gtactgatca
      121 tcggattcca gctctcgcca catatcccga tccttgcagc tttcatgtgt ttgttgtttt
      181 atggcagatt taaaaagttc acatgggatg agatccatga cgggatcatc aaaggaatca
      241 ctccagggat cattccaatc ctgatttttc ttttgattgg tgtcttagtt gcttcatgga
      301 ttttatctgg aaccatccct acgattatgg tttatggatt taaacttgtt tctgtgcgtt
      361 tctttttacc gacagcattt cttgtttgtg caattgtcgg agtgactgtc ggcagttcat
      421 ttacaacgat ttcgacgatt ggaattgctt ttttggggat cggtcattta cttggattca
      481 atgatgcaat gactacaggc gcagtcgttt ccggtgcctt tttagggaat aactgctcgc
      541 ctttatcaga tacgaccaac ttggcagcgg gtattggagg agttaatcta ttcgaacata
      601 tcgctggtat gcgttatacg gatttcccag cattcgtcct ttcgttgatt ttttatacga
      661 tattaggaca taacagtcat tcagccgatc tagctagtat caatgaaatg atccaaaaca
      721 tgaaagcgag cttttggatc tctccttgga cattgattcc actagttatt ttatttgggg
      781 gggcaatcaa aaaaattccg gctatcccta cattactagc gggatcgaca gctgctctcg
      841 ttctttcttt tatccatgag aaaagtttga cggtcggaaa agcagcagac atcttgatga
      901 atggttatgt cgcaaataca cctgatccaa agctagatga actgctttct cgaggcggga
      961 tcatgagtat gttaggttct gctagtttga ttttacttgc attggcatta ggtgggttac
     1021 tgatcaaata tctgatcgtt gataccatcg ttcaagaatt aaaagaaaag atggaccgac
     1081 cttctcgttt agtcgggttt actgccttga gctgtatcgg aatcaatctg atcgttggag
     1141 aacagtatct gtccatcatt cttccaggag aaacattcaa gcgttctttt gatgacgttg
     1201 gcttatcaaa aacctatttg acacgaacac tagcggattc aggtgcgacc gtcaattctc
     1261 tcgtaccgtg gggagtcagc ggcacattca ttatgggaac gatgaaagtt agcgcgttgc
     1321 attacttgcc attcgccttt ttctcgattc ttgcacctgt ctttacaata ttaggcggtt
     1381 ttttattgaa tcgtcgacgt gtaaaaaatt gaaggaagga aaaaagaggc tgggacagaa
     1441 gcgtttaact ccaagaaata agaagaaact caagaaaatt gctttttaaa tttttgtgaa
     1501 tttcagctta tttccgaagg agttgcttct gcttccgccg tttatacgtg tttagagcgt
     1561 gagacaaaag tgttctttac ttttgtccca cgctcttttt tacagataaa caatgtgtta
     1621 gaagtagtat cttcttttac ataaaaagct gaccatagga taaatggtca gcgtatttag
     1681 tgagtcagct atttagtatg ggttttctaa aggaacgact gtctctcttt tgatcaagcg
     1741 atgagggatg accaaacgta cgccactgct caattcttca tggatcaatt cgcgcagctt
     1801 ttgcatagcg acacgtccta attcggagat atcgatatcg atacttgtaa ggtaagggtg
     1861 tgttaatgtt gagaagatcg agttgttgaa gctaatgacg gagagtgtct ctggaatgac
     1921 atagccatac atttgcgcca actgcatcgt gcgaagggcg aagatatcgt caatgaccac
     1981 caatgctgtg gcttcgtttt ctttcaacgt tttctcaaag gacagataat cctccggatg
     2041 ctctagtact acactggata acgcaggaag accagccatc atcattgctt tttgataacc
     2101 gaaatatcgt tcgaaataca aactttcatg agtcgtgttt gtcacaaaca ggatattctt
     2161 atgtccattc tggatcaaaa attctgttgc ttgtttacct agaagctggt tatcattatc
     2221 tacataaacg atttcgttct catgatgata aggctgtccg atcaaagtga aagggatgtg
     2281 gttttggtat aaataatcaa tgacagtatc ttgactatct gaatacacta gaataaaacc
     2341 atctacttgt ttttgtaaat gcatacgctg gacgttctct aacagcaatt caaaattttt
     2401 agcagtagcg attgctgtag tcatatcata attccgcgct tcttcgttga ttgcttccat
     2461 gatctcaaga taaaatgggt taccgatccg ctcttttgaa tcaagagggg gtaagattac
     2521 gccgatggca ctggaaatgc gttttcctag attgcgggca gtcatgttag gaacataacc
     2581 tagttcatcc ataatttttc ggactttctt ctttgttgtc tcggaaatac taggatgatc
     2641 gttgatgaca cgagagacgg tcgaggtggc aacaccggct tttttcgcca catcttttac
     2701 ggtaatagcc atgataaaaa cacctttctc ttgttattgt gcagagaacc gataaatcgt
     2761 ctgactgatc cgttcttgac caggatggag gttgatcgat ccaaatttgg ggaaatgaac
     2821 gatatcaggg atttcttgcg gttcgattgc taatccgtag tttgaatgca tctgttttcc
     2881 attgacagag aaatcagctt cgaatccagt cgtagaaaat aataccatac ttttattaga
     2941 agttgctata gtcatttggc gaccagaatg cttctcgaat aattgtaagg aagttttgga
     3001 aagcctagga tgatgcaaaa gaaatacatc atctagtcca tctggataac atgcaaggat
     3061 ctcttgcagt gttggggatt ttctaaagtc gattggcagt ttttcttttt ttgtccaatt
     3121 tccagtaggc agtttttctt gatctaattc aagcacacca tctaaaaaga ccgttaactg
     3181 atgttcatag atgtctcttg ttccatttcc tgaaaggttg aagtaggcat ggttggtcgg
     3241 attgcagatg gtttcaacaa ggctactagc agaggttgtc atctctaatt cgttttttgt
     3301 taaacggtaa gtgatcgtag cagtgattgg tcctggatag gtagaaaatt catcttttaa
     3361 gtaaaagacc acacctattg atgatggagt tttgaaaact tctacttccc aaaattggaa
     3421 agaccagcct ttcgtgccac cgtggatatg gtgtgatccg cagtttttct ccaatctatg
     3481 ctcaccccaa gaagcatccc ggatccttcc ggctacaggt ccgacagttg ctccaaaaaa
     3541 gcttttgtct gttagaacat cttcgaaacg atcgtaagac aataaaacat tttctgattt
     3601 tccttctttg tctggtgcga agatttggtg caggcgggca ccgtaattga gaagaacgac
     3661 ttctaagtag tcgttcttca atgtgatttt ctttatttca gtctctggaa ctggtacgac
     3721 ggagatctct ggattatcca tggtcatgcc acttttcttt caagtaatcg atcgtaagaa
     3781 aagtcgtatc agggacaagc gggatctcct ctccaaggtc ttcagcacgt cccacgccaa
     3841 ttggttgagc gccacttgag aggatggctt ggataccggc ttgcgcgtct tcgatcccga
     3901 tacattcttc tgcttttagt ccgacagctt ttgctgcaag gaggaagata tctggcgcag
     3961 gttttccgtt tgttgcttct gccgggtcgg caatagcatc aaagtaaggt gtaagaccca
     4021 ttttttcaag taggaatggc ccgtttttac ttgcagaagc aagagcaatc ttgatttttt
     4081 cttcttttaa agaatccagt aaaggcacga ccccggggaa gacatctttt ggttcgatcg
     4141 tctggatcat ctctaaataa taatcgtttt ttcttttcgc taattctgca aattcttcct
     4201 ttgaaaaaga gtgttctttt ccgccataag ctaaaagcaa agagagtgag tcttctcggc
     4261 tgacgccttt tagctgttcg ttgaatgtgt ggtcgatcgt aatgccgatt tcctgaccaa
     4321 gctttcgcca agcacgataa tggaattcag cagtatcggt aatgacaccg tctaaatcaa
     4381 acaatacccc tttaaacatt tgcttcctcc tttcttagcg ttatttctag acgatccgct
     4441 aaagaataag actgttcata gacgtaaatt tctagaggag aaccttctaa taactcgaaa
     4501 gtaacttgtt catctgtgac tgagatgaac aataaacgtc cgcgataatt gatatggaaa
     4561 gaataagctt tccaagtttt tggcagaaat ggtgcgaatc tcaactgatc atgggcagtt
     4621 ttcatttgag caaatccttg gacaatcgac aaccagctac cagtcatgga agtgatgtgc
     4681 aagccgtctt ctgtgtcgtt attgtaatta tccaaatcca agcgagctgt tcgctggtac
     4741 atttctacag ctttgctttc cattcctaat tctgctgcta aaatcgaatg gatacttggc
     4801 gaaagggaag actcatggac agtcattggt tcatagaaat caaagttttt ttgcttttct
     4861 tcttttgtaa aagtatcatt gaagaaataa atcccctgta gtacatctgc ctgcttgatg
     4921 aagcaagatc taaggatttt gtcccaagac caatgctgat tcagaggaag atcgcttgtg
     4981 ggaatatcgg atacaggcat gagatcttta tctaagaatg tgtcatgctg gacaaagatt
     5041 cctaattctt cgtcaactgg gaagtacatg ttctctgcga tatctttcca tttggctagt
     5101 tcttcttcgc tgatagtgat agcagcttct ttttgataag ttaaataatt ttctcgcgtg
     5161 taacgcaaga cccaagctgc gatcgtattt gtataccaat tgttattgat attgttctca
     5221 tattcgtttg ggccggtcac accgtggatc atgtatttat ttgctcgttt tgaaaaatgg
     5281 acacggtctg cccagaagcg tgcgatttct gctaaaactt ccagtccttc atttttcaaa
     5341 tattccgtat cgccggtgta attcgtataa ttgtagattg cataggcaat cgcgccattt
     5401 cggtgaatct cctcgaatgt gatttcccac tcgttatggc attcgacacc agtgaaggtg
     5461 accataggat aaagcgcgcc ttttaatcct tgttgctgag cgttgtggat tgcttgcggc
     5521 agttgattat gccgatattt cagcagattc ttagttactt caggtttggc taaagcaaga
     5581 taaagaggga cagcatacgc ttctgtatcc cagtaagtgg ctccgccgta tttttctcct
     5641 gtgaatcctt tggggccgat attcaatcgt tcatcttcgc cgtagtaagt agagaatagt
     5701 tggaacaaat tgaatcgaat accttgttgt gcttcttcgt ctccttcgat gaccacatcg
     5761 gcaagcttcc atcgttctgc ccaagccgct gtttgctctt cttttgcttg gatataattg
     5821 tttgtctggt tcgttaattc tgagacagct ttttctgctt gctgcgcttc tggaatatct
     5881 ctactagtaa gaacgataat ttctttttcc actgaccatg tctcaccttg agataattct
     5941 gcagacaagc aaccatgtaa tgctaaagta tcttcgtgat agtcagggat gactgatttt
     6001 ccattaacga aatggcgcat tgctgcagta acagtaaatt gttcaatccc aaagttgttt
     6061 ggaatagttt tagtcgtcaa atagccgatt tcttctatag ttccacgatc aatctcattc
     6121 caaaaatgtt catcatagtt gctgtcttcg ttttgaacat ttccatccaa ttttgatacg
     6181 agtttgactg ttccgctacc ttcaagcatt tctatagtta aatagatata agctgattct
     6241 tttttgacaa tgctcagaaa acgttcgaag gaaatgcgta ctttattagt agaagtagtg
     6301 attgtgaatg tacgagataa tacaccattt ttcatatcta attcccagta aaagtcttct
     6361 ggttccaaag aagccaagtc gatcagctga tcgttgatcg aaatatctat cgcgataaag
     6421 ttcaaggcgt tgatcacttt tccaaagtat tctggataac catttttcca ccagccgaca
     6481 cgtgtcttat cgggatacca gacacccgcc aaataagtac cttgatggtg gtcccctgag
     6541 taagtttctt caaagttccc gcgcatcccc atataaccgt ttccaatact tgttaaagat
     6601 tcttgcagtc gaagattttt tttatctaat tgtgtcgtgc tgattttcca tggatcaata
     6661 gcaaatagtc gtttgatctg tttcattttt ctcctcctaa tgagctgttt tatacgttca
     6721 taataaacgc aaccgattgc acaagtcaat agacaaaaga aaatatttca tagaaaaaag
     6781 cttaaaaaaa taaattttta ggagaaaatt atagaaggga acacacgtat tataggtttt
     6841 atagaatggt atagacagaa aaataaaaaa taaagcattt acaaaaaaga aaacgcacgc
     6901 tataatacgt ttaacgaaac cgattgcgta aaggagctaa acggaatgaa aaagatattt
     6961 agttttgagt tttggcaaaa atttggaaag gctttaatgg ttgtggtagc agttatgccg
     7021 gcagctgggt tgatgatcag tatagggaaa tcaattccct tgatcaatcc tgattggacg
     7081 ccgcttgtca caacgggcgg agtaattgaa aatattggtt gggcaattat tggtaatctt
     7141 catattttat ttgctttagc aataggagga agttgggcaa aagaaagagc aggcggagca
     7201 tttgcagctg ggatctcatt tattttaatc aatcggatca ctggggctat ctttggtgtc
     7261 acaagtgaca tgcttgcgaa tgaagatgca tttacccaca ctctgttcgg tacgaagatc
     7321 atggttaaag gattttttac aagtgtattg gaagcaccag ctttgaatat gggagtattc
     7381 gtagggatca tcgctggatt tgtcggggca atggcttata ataagtacta taattataga
     7441 aaattgccgg atgctttgtc atttttcaat ggaaagcgct ttgttccgtt tgttgttatc
     7501 ttatggtcaa caatcgtggc attgattctt gctgtggtgt ggccaaacgt acaggctgga
     7561 atcaataatt ttggtttatg gattgcagaa tcacaagaaa gcgcaccgat tctagcaccg
     7621 tttttatttg gaacattaga acgtttacta ttgccatttg gattgcatca tatgctgacg
     7681 attcctatca actatacaca gcttggcgga tcgtatgaga ttttatcagg cgcacaggcg
     7741 gggacacaag tatttgggca agatccgtta tggttggctt gggccactga tttagtgaat
     7801 cttaaaggtg caggggatat gtcgcaatat gagtttgtgt tgcataactg gacgccggct
     7861 cgtttcaaag taggacaaat gattggttct tcaggtatct tgatgggaat ggcttttgcg
     7921 atgtatcgta atgtcgatcc tgataagaaa gcaagatata aatcaatgta tttttcagca
     7981 gcgttggctg tctttctaac aggtgtaaca gaaccattgg agttcatgtt tatgtttgct
     8041 gctgtgccat tatatgtcat ttattcagtg atccaagggg ctgcatttgc gatggcagat
     8101 atcttgccat tgcgggtcca ttcatttggg aatatcgaat tgctgactcg gacaccgtta
     8161 gctatcaaag cgggtctagg tggagatctt atcaacttcg tgttgtgtgt gatcgctttt
     8221 ggtgttgtta cgtatttctt agcaaatttc ttgatcaaaa aattcaactt tgctacaccg
     8281 ggacgtaacg gaaattacga caatgacagt gaagaaaccg ttgtatctaa cagcggaaca
     8341 ggaacagcag atcagcaagt ggtccagatc attcatttgc tgggaggaaa agaaaatatc
     8401 aaagatgtcg atgcttgtat gactcggtta cgcgtaagtg taaatgatcg agaaaaagta
     8461 gggactgaag aagcctggaa acgagcaggg gcgatgggat tgatcgtcaa agacaatgga
     8521 gtccaagcag tttatggacc aaaagcagat gtcttgaaat cagatatcga agatctgctg
     8581 caatcaggag cagagattcc agagccagaa atggtttcta caggaaatgg acaagcaggt
     8641 agtaagcaat acttaggtat agaacaagaa ctagtttccg cagcttctgg agaagtgatt
     8701 cctttatctg aagtaaaaga tccggtattc tcacaaaaaa tgatgggtga cggctttgct
     8761 gttattccaa catcaagaga agttgttgcg ccgatcgctg gaaaagtgac aagtattttc
     8821 cctagcaaac atgcaattgg gctggaaacg aaagatggta tcgaagtttt gatccatatg
     8881 ggaatcgata cagtccaaat gaatcagcca gcttttgaga ttgctgtcaa agaaggccaa
     8941 gaagtaggaa caggaacgaa attagctgag atggatcttg atgtgatcca aaacgaagaa
     9001 aaagatccaa cgatcatgat cgtatttaca aacgataaag tagaagaagt agtgatcaag
     9061 caattaggta cagtgacagc tggtaaagtg atcggctcca ttaaaatgta aggagaggtt
     9121 gtgaaaaagc tgtcctgcat caagtcataa gaacagccaa acaaaaatag ctcctcctat
     9181 ttttcgtttg gttgggctta ttaccgagaa gcagcagttt gaatactgtt tagtggagag
     9241 gtcgtgaaaa agctgccctg caccaagtga taaaaacagc caaacaaaaa atagctcctg
     9301 gtccattgag cttattactg aggagttagc aggagaacac tatttgctgg agaggttgtg
     9361 acaaaaattt tgtcacaacc cttttgtttc gaaatgaaga caaggagaaa accaatgaaa
     9421 ttcatgacac tcaacacgca tagctggctt gagccagaac cagagaaaaa attgcaagaa
     9481 ttagcagata agatcctgtt agaagattat gaagtgattg ctttacaaga aatcaaccaa
     9541 ttactggaat ctgaagaagt agaacctgcg aagctaatga agttctgtcc ggtaaagaat
     9601 caagtaccta tccgtaaaga taattttgcc taccgtttag ttcagctttt aaaggaacac
     9661 ggaaaagagt atttttggag ttgggaaatg agccacatcg gttatgataa atatgaagaa
     9721 ggaaatgcac tgcttacgaa aaaaacattg gaaagtcagg tccttaccgt ctcccaattt
     9781 caaaagaaag aagattatca gacacgcaag atcttgattg ggaaaacaaa gatagatgat
     9841 caggacattt ttgtctcgag ctgccacttt tcttggtgga cagataaaaa aagtggcttt
     9901 tattttgagt ggaaaaactt ggaaaactac tttttggaaa ctcgcgtacc actttttttc
     9961 ctaggtgatt tcaataatcc agtagactct caaggttatt atactgtaag agaaagttgc
    10021 cttcttcttc aagattcgta tgttgtcgcg aatgaaaaag gaaaagcagc tactgtggaa
    10081 aagaaaatag atggttggga acaaaataca gaaaaattgc gtatagattt tattttcgtc
    10141 cctgaaggaa tgcaggttaa aaaatatcaa cggatttttg atgggatcga tagtccaatc
    10201 atcagtgatc actacggggt ggaaatcgaa ttagatgtga acgaataaaa aatataacat
    10261 ataacataaa aaaactgatt aaaataaaac tctccaaacg attataccgt ttggagagtt
    10321 ttttgatcgg atgtatttat cccttttgcc taagcacgta aaagcttgta tctatgataa
    10381 ataaataaac atagcaaggt aaaccagcca atcaaagtaa gagaaagaat gaaatagaaa
    10441 tagattggcg tttgataatg aagcgtgagc tcgttgattc ctttttgctg cttcacgatt
    10501 ggggtcccga tatctgttac ttcataatca gtcaatgttt ttccattttg ctgtagcaca
    10561 gtccgatcgt agacgataac agggatatga acagttttgt ccccagtgtt tttccacttg
    10621 attgtcaaaa gaccgcctgg atgtgttttt ataaaagttg tttcgttttc tagtatttct
    10681 tcgttatacc ggtcgtattt attgtctttt gtctccttat agattggcag atagtcaggt
    10741 gtggtttttt ggaaaacgaa caagctggta gacatatctt tgctgaagaa tgttttcctt
    10801 gcttcttccg gcgtatcgaa tagataagta tgtcgactga caaatgtttc attttcccac
    10861 ttttccagat gctggtataa gttctggatc gtctgtgctg aaaaaataag aatgccaaat
    10921 atacttaaaa gacggaacca cttttgttca gaccactggt tcagtgaaag ggcaaggtaa
    10981 agtagaagca atagcgtaaa tggcacgaaa aatcgaaatg gaaactggat caaactaata
    11041 aaaggcacat ttttttcgat caatgtcgtc catggaatca agctagtaga aagaaaaaag
    11101 aaaacaagac ttgtgtacaa cacgattttt tggaataagg tgttcttttg ttgaaagaaa
    11161 ataaaaagca aaaaacctga taatatcaat ataggaaagg ccttagggta atggagccaa
    11221 taactgccat ccagatctat cgccttttga ctcatttctc tgttaacaaa gggaggaaga
    11281 atcttattcc cactgtaaac aatagctaat cctgcccaaa tatttgctgt cagaacaaaa
    11341 taaagcaaga ccgacttaat cagttgaagc agtgcttttc ctttttcagt ctggttaaaa
    11401 aagtaataaa gataaaaagg gatatacatc aaagctaaca tgatcgaaga cagtaaatgg
    11461 atctgtgtca taagtcccac tgagacagcg actttgataa cagggaactt tttatgaagg
    11521 acgaaatcag caatagggat catacataaa ggataaaaac aagtccccca gctagtgaat
    11581 ccttggttga tagaccagta ttgaatagaa tacgtactca tgaataaaac ggctactggt
    11641 acacttaccc aatttcgaac attgacatat ctcagtaaaa tcagcataga aaatcctgaa
    11701 ataagataaa gaatgaaatt tgaaagaatc tgataatgaa accagctacc tgcaagcaac
    11761 acgatcaatc cttgtaaata agcgaaaaat gggccgtaaa cggcattcac gatcctgcca
    11821 ctttgctgga atccataaag ggaaggaaaa taatggaaat ccccatattt aatttgttgc
    11881 gcggcatcat agaaccgatt gtaatggaat ggggcatcag cacccaaaat tagtttatgt
    11941 gtgaataaat gaggcatgag aaatgccaaa gcaatgaaaa aaattgctaa aaatgggcca
    12001 tattttttca attgtcgaac tcctttgcaa actttagata aattcatcat atatcctatg
    12061 cgagaggtag gcaagaaatt agaaaattca tgaaaatatt tatgaatttt acaagaaaaa
    12121 cataagtgaa agttctaagg agagaggatg cgacataagt tttgttgcat ctccttgttt
    12181 tgaaacagaa tttttcttaa tactcgaaac aaagtagctt tttcatgacc tctcggtaaa
    12241 cggtgttcaa tcagctgctt ctcggtaata agctcactag cctagaaaat atgagaagct
    12301 attttctgac tagcgctctt attactcaaa gcataacgca gttttcacaa cctcttcctt
    12361 aaacggtgtt caaaagcttg catctgcggt aataagccca acccaacaaa aaatatgagt
    12421 agctattttt ttgggctgta cttattactt gatgcaggac agctttttca caacctcatc
    12481 ggctttcatt ttctattttt ttcctgaacc catataataa aagaaagaac aaaaaaactt
    12541 gcaagggagg acacatgtga agcagagtaa gcaaaaacag tctcgtcgac ttttgtttcg
    12601 tttgttttta ttaatatgta tcgtcgtagg gttactgatc gctttatatc cattttatgt
    12661 ggattcttta aatagtttta ttgatcaaaa acgtatcgaa caagtacaaa aacggaccgc
    12721 agctgaaatt gaagtgcagc gaaagaaaat ggaggagaaa aaccaacgat taactgacca
    12781 aggattcaat cctggtactg atcctttcaa tgaaaagaac agaaatgaaa gtacaacatc
    12841 cagccaatta gaggaatggc tgatcggaag tatcaatata cctaagatcc aattaaatat
    12901 ttcactttat gatcggctca atggtaggat ccttgaaaat ggagcaggcg tcttgcaagg
    12961 aacctctttc ccgcttggtg gaaattcgac gcattcagtg atctctgctc acagcggttt
    13021 acctaatcga cggttattta ccgaattaga tcgtttagaa aacggagaca cgtttatttt
    13081 gactgttttg ggggagaaat tggcttatca agttaaaaat atacaagtgg tactgccaga
    13141 tgacacgtct gttctaacga tttcagaagg agaagactta gttaccttgc ttacatgtac
    13201 gccgtatatg atcaacacgc atcgtttgct agtgacagga catcggattc cttataacga
    13261 atcggtaaaa aaagaagaag gaaaaggaaa tcaggaaaga accatgcggc aatggtttat
    13321 tcttgcagga acgataatag ctgtagtcat actgttagtg tttatcggac gactaatcta
    13381 tcagtataga ttaagtaaaa aagtgcttga tttttcattt attattagtg attcgtcagg
    13441 gaaaccggta aatggtagtt cattcatttt gaaacataag aaaaaaacac ttactagaaa
    13501 tggtgtgccg ttttcagtac aaagcgacca tcatgggaaa gtcaagctgg atcaattgcc
    13561 tggtggaact tatcgaatcg tttcagctga tgatcctaaa gttgctgttt cttttggtat
    13621 tagaaaagta aaacaagaga agatatactt ttttgagggg cgaaaacttg taaaagagct
    13681 tcaaaaaaat ggtttttatt ttaaaatcaa tgaataagta aggagagaaa aaatgatccg
    13741 cacaacaaca aaattgtctg ccaaagaact ggaatctgtt ctatcgattt ggctgcatgc
    13801 taacttggat tctcatgaat tcattccatc aacttattgg gagaatcaag tagaatctgt
    13861 taggaaagct ttaccagatg cagtgattta cttagcagaa atagatcaag aaattattgg
    13921 ttttgctggg gtgattgatc agtttatcgc aggaatcttt gtgaaaaggg aataccggca
    13981 acaaagaatc ggtacgcaac taatgaaaaa aataaaagaa accaataaaa cactgacttt
    14041 gacagtctat caaaaaaatc aatcagctat tcatttctat ctttcacaag gttttacaat
    14101 tcaaacacag caaaaagatg aagcagtaaa tgaggaggaa cttgtgatga aatggaatca
    14161 aaacgctgat ttttgatgaa cagaataacg aaataatgct cccagcctaa ttttttgctg
    14221 ggagcattat ttcattttga agtcactaat ttaactgtgt gaatatgcag ttgttacaat
    14281 ctttgataaa cggtgttcaa tcagctgacc ctcggtatta gctcaaaaaa cggcaaaata
    14341 tgaggaacta tttttccatt tgtttctcta atactcaggt caaaacgctg atttcacaac
    14401 ctcttgataa acggtgttca aacggctgct tctcggtaat aagcccacta gcctagaaaa
    14461 tatgaaaagc tattttctaa ctagcgttct tattactcaa agcataacgc tgatttcaca
    14521 acctcttgat aaacggtgtt caatcagctg accctcggta ttagctcaaa aaacggcaaa
    14581 acatgaggaa ctatttttcc gtttctttct ctaatactca ggtcagaacg ctgatttcac
    14641 aacctctctt tcacaacctt attttactcg tttataattt tcatcgaagt attttccgct
    14701 acggatatca tctggcattc catcgtatgg ttcttcgcta ataacatctt cattgtctat
    14761 acctgcatca cccatataag tgatcgtagc aaattcagga acaagtaatt ttggataagt
    14821 ttcatatttt tcacgagctg cttccatttc tgcgatatgt tcgttttgga aagtaacagt
    14881 gatttctgga tgttcttcaa cccatttagg gaaaaagatc attccgtgaa gtttcttttc
    14941 atttggcata aagtccaatg ccacgtctgt ccctgttggc tctgtccaag tgattttgaa
    15001 tacgccgtcc gtcaatttaa cgatatcagc ttcttggtct tttacccaac ggcctttgac
    15061 cattccgcca tggatacggt aatcaacagt atggtcattt ttggcatacc attcatattc
    15121 ccaaccattg tcatacgtat agataaagtg agttccaata aaatcttcca attctttaaa
    15181 ttctttcatg tttaagcatc tccttataaa ttaaaacatg taataaacta catgttttcg
    15241 attactcatt tatgatagaa tggatttaaa gatttgtcaa ggagggaaaa ctgatggcaa
    15301 gaaaaaatac acttcgatat attttgttag ggttattaag taagaagaag atgacaggat
    15361 atgaattgaa tcaatcgttc aaaaatgaaa taggagaatt ttggcaagca aaacatagtc
    15421 agatttatcc tgaacttgca aaaatggaag agcaaggaat cattcagcat caagtagaga
    15481 tcacaggtga aaaattggaa aagaaagttt atgaattaac agaagaaggg aaggaacaat
    15541 tggcagagtg gattcataca cccaccaatg aactaccggt taatcgagac gaatttgttc
    15601 tgaaattgta tttcgtcaaa gacgtgaatg atccggcatt agtagaaatt attcagcagc
    15661 agcgtgacct tcatgaagaa aaacgacttc atctattaga gcgaaaaaaa acgatctttc
    15721 ctactgaaaa agaaaaacat gaaaattacg gacactacct gattttagcg catgcgatca
    15781 atcgggaaac agaatatgca aattggctaa cagatgtatt agaagaaagt aaccgaaaaa
    15841 aataaaaaaa tatccgaaca gtgatggaga attcctttct atatgaaaga aacgcagatc
    15901 accgttcgga tattcttatg ttcaaacagg ccttttttca agtatttatg tagcatctac
    15961 ttattaaaaa gcttggtact taggagatta gtggcgttta gagttctttt aacaactgtt
    16021 cgtagtcagc tttttcatcg acaggaagga gcttgtaagt taattcgtct gtctcgttgt
    16081 catgaatgat gtacatctta gcattctctt ctttgaagtt accgatttgt aaaatcgtat
    16141 agcgttcgtc gatcaattcg atatctttga ttgcttttga aaaaacttta cggacatggt
    16201 gcattttctt ttggcggatt tctgcctttt ctgcagcttt tgacaaagta aatccgtcat
    16261 ctaaatattt tttgatcagt tctactttta tgactgtagg taaacgatat tttctaggac
    16321 aattcgcatc agcttcgatc gaacgaatga atcccttttg ttcccaatac cttaattgac
    16381 gtggagacac acctacgata tcacttaatt cactgatgcc aacaaccaat tgatcatttt
    16441 ccaacaaacg tttaagggaa gccccaacca tttttgtcac tccttttgtc ctcttgcttc
    16501 ccttaattat atccgtatta acttatgtgt caagtaggtt gacaaatagc gaatttagga
    16561 ctaaagtatt ctagtagttt cagaaaaaat tcagaaagaa ggagaaatat gagtaacaac
    16621 caacccgtag atatttacgg aaaaccatat aatcggacac ttttagttgt tgtcttatta
    16681 attggtacat tttgtaccgt tttgaatcag accttattga cgacagcttt tcctacattg
    16741 atgaaagctt tcgatatttc agcgtctgat gtgcaatggt taacgactgg tttcttgcta
    16801 gtcaacggga tcatgatccc aataacagca tggctgatca ataaattcag ttcaagaaat
    16861 ttatatcttt ctgccatgac gatctttttg atcggaacga ttacttgctt tacagcacct
    16921 aattttagta cattactaat cggtcgtttg atccaagctt gcggtgtggg agtatcgatg
    16981 ccattattgc aaaatatcat gctatctatt ttcccgccag aaaaaagagg atcagcaatg
    17041 gggatgtcag ggatcgttat tggacttgct cctgctttag gccctacatt atctggttat
    17101 atcattgata actaccattg gcgtgacttg tttggtatgg tactgccaat cgttgttctt
    17161 gtcttggttt tagcattctt cctaatgaaa agtgttattc cattgtcaaa tcctagcatt
    17221 gatattttat ccgctatttt atcaacgatt ggattcggta gtttacttta cggattttct
    17281 agtgtaggag atgacggctg gggaagcttg aaagtaattg gtttcttagt tgttggtgtg
    17341 attttcatcg ccttgttctc atggcgtcaa ttacatttgg aacatccatt cttggaactt
    17401 cgtgtattca aatcatctac attcacgatt gcagctgttt tagctggtgt aacaaatatg
    17461 gcgatggtag gggcagaaat ggtcgtacca ttgtatattc aaaatattcg tggagaatca
    17521 gcattccatt ctggcttgat gttgttgccg ggtgcattga tcatgggggc tatgatgcct
    17581 gtgacgggtg cgattttcga taaatacggc gcgaaacgtt tagccatcac agggatgttc
    17641 attttgacag cggcaactgc accatttgct ttcttgacaa aaacgactcc agttttatat
    17701 atcgtgatcc tttatgcgat ccgtatgttt gggatctcca tggtcatgat gccggtaacg
    17761 acttctggta tgaatgcatt gccaaataac ttgatcagtc atgggacagc ggtaaataat
    17821 acattccgtc aaatcgcaag ctcgattggt acagctattt tgatcagtgt gttgacgaat
    17881 gtgacaaaag caaatatccc aagcaaatct gtattggata atacgccatt agcttataaa
    17941 gatcaggcaa tcaatgccac actgtcaggt taccatgccg cgtttatcgt agcgatcatc
    18001 tttgggattc ttggctttat tattgccttt ttattgaaga aaaaagaacc tgttctaatg
    18061 aaagcggggg ataatgcatg attattggag ttttgattgt cagcttgctt gcttttgctt
    18121 taacgaacgt gttcgctaaa aaaacatggc aaaccttttt atctttgatt ttcggactaa
    18181 tcttcgtcgc ttcactaagt ttgatcgtcg ctaatttgtc caatcacttt ggaatggaaa
    18241 aagtaacgga aacaaaaaca gaaaaaattg tttccagtgc tgattcccaa ggagcagata
    18301 tgcttttgta taaagcttta gggaatggaa aagaaaaagt gtatctttac cgaacaaatg
    18361 aaaaacaaga aaaaccaaaa gcaactggta cggataacga aacaaataaa gtagaaaaga
    18421 cagacggcga tgctgaaaaa gtgacgaaaa ctacttattg ggaatacaaa aacgacatgt
    18481 ataaattctg gttcaatatt gctgataaca atcacgaata tgacagccga gtgaatacat
    18541 tcaaaatccc agagacatgg gtagaattaa gtacggacca agcagccaag ttagctgaat
    18601 tagtgaagaa acagcaaagt acgatggaaa gtgaagcaaa agcttatgtt caagacggta
    18661 tggtaaaagc aatgactgaa aatccaaaaa tgagcaaagc agagcaagaa caacgtacga
    18721 aagccttagc tgctgaattc caacaacaag cattcgcaaa attagtgaaa gaagcaaaag
    18781 gcgaataata ttttgaacac catgtaggag gttgtgaaaa agctgctctg catcaagcag
    18841 taagaacaat cagataaaaa tagcactcca tatttttcat ctgattgggc ttagtgccgt
    18901 agatgcaagc ttttgaacac cgtttaagga agaggttgtg agcctgccgt ttaactctga
    18961 gtcacaagga gcaatttcaa aaaacagctt ctcatgtttg ttgactattg tgacttgtga
    19021 ccgaggagtt ggcaggagaa caccgtttat tcgaaaaaag gaactgcgac aagacttttg
    19081 tcacagttcc ttcttttttt tgctatgcta tactagatgt aaaaaatagg agaaataaaa
    19141 tgagggaaat ttattctttt gaatcaaaaa tctatgcttc cgaagtcggc aagggcgggg
    19201 catatattat ttttccgtat gatataagaa aagaattcgg tgctggaaga gttaaagtcc
    19261 aagcaacttt tgacaatgtg ccgtatgaag gcagtatcgt gaatatgggc gtgaaaaatc
    19321 cagatggttc agtctgctac atccttggac tacgaaaaga tattcgtaaa aacatcggaa
    19381 aagaaatcgg tgatattgta gcagttacag tgaagcaaaa ataaaagagg ttgtgacaaa
    19441 agacgtgtca caacctcttg ataaacggtg ttcaaaagcc agtttctcgg tagtaagtca
    19501 aatttatgca aaaatgtgga aacccatgtt tacaaaattt ttcttactac tcgaaacgaa
    19561 gcggctttat cacaacctct tgataaacgg cgttcaatca gctgtccctc ggtattagct
    19621 caaaaacggc aaaatatgag aagctatttt tccatttttt tctctcatac tcaggtcata
    19681 acgctgattt cacaacctct tctttcataa tggtttttca ccatctttat aataaactgg
    19741 ttatttgata tggaaatcta ttttttccaa ccaatctaaa atcttgtaac ctaactcttc
    19801 tgacatcgga aaagaggcgt tgatttgtgc attggagata tggtcaacat ggataccgga
    19861 agtgatcgta caacttcccg gaacggcagt tttgatgatc acagctattt tttcggctaa
    19921 gacatcgtct ttatggaacc gaccatcgtg gctagggaaa cgtacagttt gcatctctgt
    19981 atcacgagaa aatgtagtga ctgttccgat atgtggtgta tctccgcctg ttaaagtgat
    20041 caataagtct ttaccgatta ctttaacagc agcttggatc gtgaaaccta gtttggttac
    20101 ttcaactatc gtttcttttt ccatattaat caccctgcca acgttttgaa tgctcattta
    20161 caatttcaaa ttgatccaaa agtttcattg tatggtgatt aacaagatct tggatcgttt
    20221 gaggctgatt ataaaaagca ggaattggtg gtatgatttg cacacctagt cgtgctaatt
    20281 tagtcaagtt ttccaagtga atggcattta atggcgtttc acgaggaaca atgactaact
    20341 ttcgttgctc cttcattgtt acatcagcag cacgtgcaat caggttgtcg cctaaaccaa
    20401 cagagatacc tgcgactgtt ttcatacttg ccggtacgat gatcattcca tcggtcaaaa
    20461 atgatccgct ggcgacagca gcacctaaat ctttgtttga ataatggtaa tcaaacaggc
    20521 tttcgaattc agttagtgat aagtcggatt ccagctttaa gttctgtttt gcccatggac
    20581 tgatgattcc gtgtgtttct atcatcggat attcttttag tttcttcact aggttgatgg
    20641 cataaatggt gcctgaagcg ccacttacac caatcacgat ttttttcttc cgttgtgcca
    20701 attgttccat tttccgcact cctttttatg atgtcaaaac agttgcagat cattcattat
    20761 ttcaaatatt tttcccaatc ttctacttct tggaattttg cacgtacaaa atgttctttc
    20821 atatcgaaag gaactgtacc gtcaaagata gtttttgcac ttatcccacg gaaacgaata
    20881 gagccaggat tatattctgg taattctgat gggtccaatg gatggttcct cattcctggg
    20941 atcacgatga tatctttatc tccttggaaa cgagtgttga aagtccaaac tacatcgttc
    21001 atgtcgaaaa tatcaacatc ttcatcgact aaaatgactg tcttcaattc tttgaaggct
    21061 gataaagcaa gaatagctgc ttgacgctga ataccttcat ccgcttcgtt ttctttacgg
    21121 atttgcatga tggtcatcaa tttaccacca cctgcaggag gattgtagac atttactact
    21181 tttcctggaa tagctttatc gaccaaggca agaatacttg cttctgtagg aataccggcc
    21241 atagatacgt gttcttcact gggaccaatc gttgtttgca tgattggatt gtcttttcgg
    21301 tgagtaactg ctttgacttt cactacttgt acagctggat tagcatcccc agtatagcca
    21361 ggaaattctg gcattgcttt tcctgagttc gtgttgatat cttcttgcat tgtttcattt
    21421 ggcatgattt ctgcttcaat gatgaattca gcacgagcaa tacccacttc atcgactgct
    21481 ataccatcaa cgatttgaat aggttcgtta cgcaaagctc ctgcacacca tagttcattg
    21541 tagccaagtg gagtggtagg tggttcgaaa gtcgtgccaa tggcaattgc tggatctaaa
    21601 ccaatattga tagtgatagg cattggttta ttcaaggctt cgaattgttt ttggaagtga
    21661 ccaatgtggc gtccgccagg catgatgtac ataccgatcg tatctttatc ttctagaacc
    21721 atacgatgga tcgttacatc gctcattgtt ttttctggat ctgatcctaa gactacaccc
    21781 attgtgatgt atggaccagc atcttcagga gtatttgtag gtgcaggcaa aatgttgcga
    21841 atatcgaagt ctgcatcggt agctagatga acgacttctt gtgctggagc gtctgctttg
    21901 tctactttca caggtttgat tggattttct acagcgtctt tcaagaaacg accaagtgtt
    21961 cgataatcat ggtgcaaaat ttcacctaca cgtttacgac tagccattgt tccgatgttc
    22021 acacgtgtgc cggggaaacc tttgatattg ttgaaagtca tagctggtcc ttcttgagtc
    22081 ggacgtttta ctgtaccgcc agcaccgata taacggtaaa caccagataa ttctgcttca
    22141 ggatcgattt caatatctgt ttcgtgatat tgacctggaa gtgtttttag ttcttcgatg
    22201 acttttctta aatcatacgg ttgatctgtc atgagagatt cctccttagt tgtctttacc
    22261 tatctatagt aaaaggtgaa aaagaggaaa acaattcaac ttgttcggta aagtattcta
    22321 caatggaatg gatgcgtttt tttgataata gaataaacta tgatatactt atcactaaaa
    22381 gaaagcgcat acttagtgtt ggaggaagga aagtgaaaaa aatggaggag tcatttccta
    22441 aagcagtaaa agtggaaaat atagcgaata ttttgaaagt tacatttgaa aacggagaag
    22501 taaaatacgt gaaatctcat tggacagaag agataaccga tgccttgcaa tttggaaaaa
    22561 aaggaagagg aaaaagaaaa aatcttctcg cactttctcg taatatgtgg attgggactg
    22621 aagtaacgat tgaagcagat ggaacagtat tcataaatgg aaaagacagg tatacgccag
    22681 aagagttgtg gtacaaagga aagaaaagta taccagaatt ataaaaaata attaaaaaaa
    22741 acagcgcgaa acaaggaaca tattacttcc tcgtttcttg ctgttttcta ctatttcagc
    22801 gctcttatga ctcaaatcta aatgtggttg tcacaacctt attctgcacg caaagcgata
    22861 gcggcgtctt ttttcgctgc cattcgtgca ggaagatgac cgccaagcat cgtcaatata
    22921 gtagagacga tcactagaat aatcgcatgg acaggattta gttgagcaac attttttaga
    22981 tccgtcatgt tgtataagat gctattgata gggaacgtag ctagccatgc aataaacaca
    23041 cctaatatcc cagaagaaat acctaaaata cacgtttctg cgtcaaatac gcgagtgatg
    23101 tcttttttac gtgcacctaa agcttttagt acaccgattt cttttgtccg ttcaatcaca
    23161 gatgtataag taatgatact gatcatgatc atacttgtta ctaaagagat ccctgcaaaa
    23221 gcaataagga cataagtgat agcatccatc aatccgccag tcagttcagt catcgttcca
    23281 gctaaatcag tataaatgat tttatcttca tctgatttgc ctttattgta atcatctaga
    23341 taatccaaga tcttttcttt gtcttcaaaa ttgttcggat aaatcatgat acttgaaggc
    23401 aagctgtctc cacctaaata actaagcaat gtttgtttgg cattttcgtc aactttttca
    23461 gtagttaaga catttacacc actgtctctt tgagctttga cgatttctga ttctttgttt
    23521 tcgttgacga tttgagtcgt taattgatcg ctataagcga ttcctggaga taagagattc
    23581 attgtagaag aagatttcac gcgtaggatc cccgagatct tcaattcatc agaagcattc
    23641 tgatacatcg catcataatc tgtattaggg ataaaattcc cagttggaag ttttgtatag
    23701 taagtattgt tgtttactaa tttgaatgtt gtaccaacga tatcatcaaa atcaagtttt
    23761 tcgtcttctt tcacatcaaa tccaagattc ttcaatgcgt tgatattagt attattattg
    23821 ccgtctacga tcagcacgac atctgttgct gaggctggat aacttccggc aagtaaagaa
    23881 taattgtctt ttaaaaagtt ttctttgcta gtgtcaagct gtgtagggaa acttgacact
    23941 cccacacctg tcattgctga catcgtacta gataaagaaa gagattccgt atcaggattt
    24001 tgattcgaga agctgacagg ctgtactttg ccatttacat cacgtaaaag attgattcct
    24061 gtagtacggg taaatccgat attattactt aagttaggat cgatgtctgt tacgtaatcg
    24121 acgtatgttt gatcaatctt attcgtgtgc tgtgctttat cttcttcgct gacttttgca
    24181 gtaatcgttt tgctgtctgg ataatccgct ttgcttgcac ccaatccggc atcgtcacga
    24241 gtctggttag tcgttacctt agaaatagta atcggaaatt tcgccatcgt ttcagcttgc
    24301 gtgttatcga tttgtttttg gaatccagaa gaaagggaca gaacgatcgc gattccgatg
    24361 atcccaatac tggaagcaaa ggaggtcaag aaagtacgtc ctttttttgt tcggatattg
    24421 ttgaaggaaa gctttaacgc tgtccaaaaa ctcatctttg ttctgcgtaa gttaaattga
    24481 tcatcttttg gtcgttcgat gtgaggatgg gaatctgtta agatcttacc atcagaaaat
    24541 tcaatgattc gatctgcgta ttgatgggcc agttcaggat tatgtgtgac catgatcact
    24601 aatttttctt tcgataactc ttggatcaat tccatgatct ggatacttgt ttctgtatct
    24661 aacgctccgg ttggttcatc gcacaaaagg atatctgggt cattggctag tgctcgagcg
    24721 atggccactc gctgcatttg tccaccagat aactgatttg gctttttatg catatgattt
    24781 gtcaagccga ctcggtgcaa tgcatcttct gcccgttttc gtttttcgtc tttagaaaca
    24841 ccacttaatg tcatcccaag ttcaacgttt tcaataatgc ctagatgacc aatcaagttg
    24901 taactttgaa aaatgaaacc gatagagttg tttcggtagg catcccagtc actgtcctta
    24961 aagtctttag tagactttcc gttgattacc atatcaccgg aatcataatt atctagtcca
    25021 ccaatcacat tcagcatagt cgttttacca gaaccactag gacctaaaat cgctacgaat
    25081 tctttttgtc tgaaagcgac agacacacca tccaatgctt tggtggtggt ttcgccgact
    25141 ttataatatt tttttatatc ttttaattga agcataatca cccttctccc gtattgaaat
    25201 attcggtata ctaataagta tatcagaaca atgatcgtag tatacgaaat aaatgttaac
    25261 tgaagatgaa ctacaagaaa aaatctagaa atttttcaaa aaacagaggg agatcaatga
    25321 atcgtatttt agtagtagaa gatgatccgc aattacagtt gctttaccgt tctgtgttgg
    25381 aacgagcggg cttttcagtc atcaccgcat tgaatggaga ggatgcgctg aaaaaactag
    25441 aagcgacacg tatagaatta atcattacag atatcatgat gccgaaaatg gatggctatg
    25501 acttgctaga ctcattacgt agcaccagat ttgacacacc tgttctaatg attacggcaa
    25561 aggccgattt tgaggataag aaacgcgggt tcaaattagg agcagatgat tatatgacaa
    25621 aacccatcga tgtcaatgag atgatcctac gtgtggaagc attgcttcga cgttcaaaga
    25681 tcaattacag cagtagcttg ataatcggac aaacaaaatt agagctagat gcttatacag
    25741 tgttacaaga tcagcattcg ttgattctgc ctcaaaaaga atttctgctt ctgtataaat
    25801 tactgtctta tcccaacaag atcttcactc gccaacagtt gatggatgat atttggggat
    25861 tagatacgaa tacagaagaa cgaacgatcg atgtacatat caaacgttta aggacccgtt
    25921 ttgaaaagac ggaagatttt caaatcatca cagtacgggg actaggctat aaggcggtta
    25981 tttaaagatg aaaaaaaagc tattttcaca attatggatc tattttgcta gtattgtctt
    26041 catttcgatc ttagtgacac tgctgtgttt tctcggtttt attttcttat tgtctcgaca
    26101 ttctatctcg cctgctgaat cggctggaaa accaacgtta tacccgttat tcgtctttgc
    26161 ggggttcagt atggtcgtgg gtacaggaat atcgattttt gttgggcggc gtatcctgca
    26221 tccaatcagt gcgctaggga caaatatgag tctggtagca acgggagatt tttcgattcg
    26281 aatggatgaa cagcagaaag tagcagaagt acagcaactg tataaagatt tcaacgttat
    26341 ggtccaagaa ctcaatagta tcgagacact gaggaatgac tttgtgtcca gtgtatccca
    26401 tgaattcaaa acaccactag caacaatcca aggatatgtt caattgttac aagccccaaa
    26461 tctctctgac gaagaacgcc aaatattttt atatcggatt atcgaaagta tcacgcagct
    26521 ttcacaatta acagagaaca tcttaaaatt gaacaaactg gaaaaccagc gtatccaact
    26581 ggaaaagaaa gagtatcgat tagatgaaca aatcagagaa gtaatcgttt tttttcagcc
    26641 taaatgggag aaagaacagc tagaattgga tatcgaactt gctgcagtaa attacacagg
    26701 caatgaagag tttttgtacc aagtgtggct gaatatcatg gataacgcca taaagtacaa
    26761 tcaaatcaat ggacagattc atatcaaact atttgagaca gccacagaga ttgtactgga
    26821 agtgaccgat tcaggtgtag gaatgaatga agagaccaga gatcgaatgt ttgaaaaatt
    26881 ttatcaagga gatacaagtc gtcaaatttc tgggaatggg ctaggacttt cactggttaa
    26941 aaaaattcta gaactgcatg atggacgtat tgattatagc agtatcgaag gagtaggaac
    27001 gacagcaatg atacggttaa gtaaacaata ggaaaaagaa taaaacccct aaaaattcta
    27061 ttgaaggttt ttaggggttt ttagtcgttt ttttgtgatt agggaaatgt tcttacggtt
    27121 cttttggcat aaaaatcgct gctttcttat tgaactacga gaaatgttag aggtgtcatt
    27181 gaaacaagga catgatgcaa gaaagagagc gaaagtcatg cgtcgctctc tttttttggg
    27241 tggatagatg gacagaaaat gtagggctta gttttcttct tgatttaaat actcccaaaa
    27301 tgtatctgaa gccaaagaat gctcaccgac tttacgagta aatgcaagat aactctctgt
    27361 tgttggagaa atagggagaa tcacagtatt ttcttttaat agattcttga ctgttttttc
    27421 cataacaata gcaatcccca tgtcatttgc aatcatattg atgatcaagt cgattcttgc
    27481 tcctttataa gagatttttg gttcaaatcc agcttcgcga cacagatcta gtacaggttg
    27541 atacaagttc gtagtggggc caaggagcaa aaagttctcc tttttcagtt cgcttagatc
    27601 caatttcttt ttactagcta aaggatgatt tttaggtaga actgctacaa aatcgtctgt
    27661 ttcagtaggc aaccactcaa tcgaacttgg tggggcctgg aaacttctag caaagtggat
    27721 cgtgtcacta tgttcattgg cgtcattgta agttaattcg acactttcca cttctttcaa
    27781 ctggactgta aattcaggat ggcgtttcaa aaactcggtg attttggaaa aacctttata
    27841 attgatcatt gtcggtatcg ttaagatatt taatgaaaga ttgttgtctt tcgtataggt
    27901 ttcaagcact tcttgcatag catggtattg ttctacgaca ttttttacat atgggagcaa
    27961 taagcttcca gcttcggtca attcgatttt tctatgggcg cgttcgaata atttgacgtc
    28021 taattctgtt tctaacgaaa gaatctgttt agaaatattt ccttgggtgg tgaattgtcg
    28081 atcagcagtt ttggtgaaat tcattgtttc ggctaaatca agaaaaactt cgaatttatg
    28141 gatatccatc atattcctcc tacttattcc aataaagaat actttaacac aaaaaatgaa
    28201 ttggtgtaat cttctctgtc tgttacaatc tttcttgcag cgaaagcaat aattacagaa
    28261 atttttctga tttttttcgc ttcgtagaaa aagagaggag ttttttgatg ccaactggag
    28321 ttttgatcaa tgtaggttcc gttttgtttg gcggactaat tggcggatta gtaggaaata
    28381 aattaagtga acattttaaa gcacagctga cgatggtttt tggtgtgtgt tcgatgggga
    28441 tgggaatcta ttccattgcg ccgatgaaaa atatgccggc tgttattttt gctttagtga
    28501 taggaacagc gattggtttg attgttcatt taggtaatgg gataaataag ggggctgcgc
    28561 tgatgcaagt acctatttct aaaatcttcc ctagtgaaaa gcttggtatg acccacgatg
    28621 aatttatcag cacattagtg acggtcattg ttctattttg tgcaagtggt acggggatct
    28681 atggaagttt agattctggg atgacaggag acagtacgat tttgatttct aaatctgtcc
    28741 ttgatttttt cacagcagct atttttgcgt gtaatttagg gtatgtcgtt tctgtgatag
    28801 caattcccca attcattatt ttttatattt tgttcttatt ggcaaaattt atttatccat
    28861 tgactacacc agacatgatc ttagatttta aagcttgcgg cggattcttg atggtcgcta
    28921 ccggttttag aatgatcaac gtgaaaatgt tcccagtagc tgacatgata cctgcaatga
    28981 tcgttatcat gccactgagc tggatgtgga caaattggat tatgccactg ttataataaa
    29041 aatcaaagag aagccatttt ttgctgacta aaaaggatca aatcttttag tcagtttttt
    29101 tgtatttgac aaactgattt tgaaactata ttatatgttg tataatatag attgaaataa
    29161 aatattacac ttgagaatag aaggtgacgt aatgcacatc cagattccaa ctgttcttct
    29221 tgatggtact gtgctagcag cattaagcaa ggaagatatg tatgggtatg ccttaacaaa
    29281 aatcgtacaa gaaagtctct ctgtcagtga atctacacta tatccggttt tgagaagatt
    29341 gaaaaaagaa ggatatcttg agacctatga tgaacctttt gaaggcagaa accgtcgata
    29401 ttactcgttg acaccaatgg gaagtcgtca tttagaagaa attattgatg aatggattgt
    29461 ttttcgagat tctttagacc ggttattgga ggagagcaca aatgaatgaa tatttgaatg
    29521 aagttgtgga tcatcttcaa gaaattcctg aagacgatcg ttttgatttg atccagtatt
    29581 atgaggaata ttttttagat tctggaaaaa cattagatca gatcattgat gaatatggta
    29641 caccaaagca gtttgcctta aaattaaaaa tcagttactt ttcagaagaa gaacaagcag
    29701 aaaacgagtt agtgaaaaat ccaaaaagac aaattcgcct gatttggtta atcattatcg
    29761 gtttatttgc ttctcctgtc ctcattccac tagcactggg gtttatattg gttattgggg
    29821 gactattggt tgctttacta gcgctcattt ttagtatcta tgttttatgt atcagtatct
    29881 taggtgttgg cctattcatg atcatctcag gaatcagtgt gtttggacaa tcgattctga
    29941 gtggattatt ctttatcggt gtcggtctgt tcgccacagg aagcgcagta tttatttcgc
    30001 cactgttgct gaaaggaaca aaagggcttt tttatgtcat gatgaacttt gttaaatgga
    30061 tgggacgacg ttttattaca aaaagagatc tgcattcagc gggcgtttga aggaggacac
    30121 ataaattgag attgaaacat tttttgatta ccggtattgg tctgatgctt actggtggcc
    30181 tcctagcagg tgcaacttat acattaggcg ctcaaaagag tctgacttgg gataatggtc
    30241 ctcggttgat cgatatggtt actgagacaa aaaaaatcaa ggatgcaaac aaaatcgtca
    30301 tccatgcaga aaatcaaaca gtttcggtca tacgcggatt ggattttgag ataaaaacga
    30361 cttatgataa gacagaaaag ccagaaataa aggagaaaaa tggcgtgttg actgtgaatg
    30421 cagtcaaaaa atcaacaggt gcaatcatta gtttagaaga cacaagtgca caaatcacta
    30481 ttgttgtccc tgcagatcat gaattatctg aattgacaat cgaagggaat aatagtgcaa
    30541 ttgatatcaa cgaagtatca atcaaaaaag tgaatactaa gacacatgat ggctgggtat
    30601 cgttcaatga atttacagga ggaacaataa ctgcgaaaga tgaattaggc tcacttcgat
    30661 tagatgaggc caatgtggat aacttgatcg tcacaggtga aaacagcaac ttccatctag
    30721 aagacagttt gatcagcaaa gaaggaaaag tcatcctaaa cggtggcaat ttatctttgc
    30781 atgagatgga aaacagtggc tatactatcc aaacgtctgg tgaatcttat attgaaaaag
    30841 actaccagcc aataacaaat actttgttag aacaaggaca gaaaaagcta aagatcactg
    30901 ctaaagacac atcgatcaat attacgacgg atcaagagga caatgaaaca gattgatcct
    30961 gtactcaact ggatatttta agaaaaaaca gcaaagatcc ttccaatctt tgctgttttt
    31021 catcgcttaa cgcacataac tatagtaaaa taagaaagaa aatatctaaa aagaaaacag
    31081 ggtgaaagag tatatgaagg tagaagaagg tcaaagagaa aagttaaaaa cagaaatgga
    31141 aagattacat acttatatca ctcaactaag ccaaaccttc tatgatccag acaaagaaaa
    31201 agtgatggtt aattacccga acaattcaga aggtcgccaa ttagagcaag tgtaccatga
    31261 agttttcaaa catttattga cggtgaagaa agagctggat tattattctt taccgattat
    31321 cgatacagga atattgaagt atgatgggaa gaaggaacga tttatcttta aatctgttcg
    31381 ggaagatttg cctctttcag cagggatgga tctagaggtc ttggtagaag actattttac
    31441 agaagaaaag cactgggttc gaacaaaatt ggattattta ccgcaggcag ccggagggac
    31501 acaggcaagc ggttggtaca tcactgaaga caaagagtta gaactagaag gtgtaatggc
    31561 gcgtattcga aaaaaaaatt aaaaaagtaa cattagatat ttattgaagg ataaaggagc
    31621 gcaggaagta gcatgagaga aaaaagagca ttttatatca atggttatgc agggattgtc
    31681 ggattggtcg tattagcttt agttggattg tttttcttct atttaggtat gtggcaagcg
    31741 aaagtttggg cacttttttt aagtattttt ctttggttga tcacgttatt gttgttaagt
    31801 tcggcaactg tagtcagtcc taatcaagca aaagtaattt tgttttttgg acaatattta
    31861 ggtacgattc gagaaaatgg ctttttcctt acgatacctt tggcacaaaa aatgactgtt
    31921 tcgttgaaag ttcggaattt caatagttct gttttaaaag tcaatgattt ggatggaaac
    31981 cccatcgaaa tctcagcagt agtagtcttt aaagtcgttg atacagcaaa ggcattattc
    32041 gatgtagcgt attatcaaga ttttgtagaa atccaaagtg agacagccat tcggcatatc
    32101 gctagccaat acccgtatga tacattcaat gagaatgatt tgacgcttcg aggaaacacg
    32161 acggcagtgt ctgacgagtt gcaaaaagag ctgcaagagc gtttagcagt agcaggtgtc
    32221 gaagtaatcg aaacacgctt gaaccattta gcctatgcaa cagaaatcgc tagtgccatg
    32281 ctccaacgtc aacaagcaaa agccattttg tctgctcgac aaaccattgt tgaaggagct
    32341 gtcacaatca ctcaaatggc cttagagcaa atcgaagatg gacaagaaat caatttcacc
    32401 gatgatcgga aagtccaatt gatcaataat ttacttgtct caatcattac agacaaagga
    32461 acgcaacctg ttatcaatac aggcgacatg aaagaccgta agtgacatac tttttgtaag
    32521 ataggaagaa ggagtttagg acggattatt gtcttgaact ctttttttag ttgttttaaa
    32581 gaaaatgaca aaattgaaag aagaatgata gttgattcga aggcagaatt gttcgctttt
    32641 ttctataatc agtatataaa gtaagagaga aggggaaaaa gtgaaaaaac ttctgatcgg
    32701 tctacttgtt ttcatcgttg tggtacttgc aggggtgaaa atcgcagatt acgtagttat
    32761 gggtggagaa gaatactatg tacaaattac gacagatggt acaaaaacag tttcaaaatc
    32821 agactctgga caagaaacag tcaactatag atatatcctg cctggctata cgaaagaggg
    32881 taaggaaaaa gaactggact tcaagggaca attgactcga ccgcttcgta aaggagcata
    32941 tttaaaaatc acctggaaca aaaataaagg tgtcacttcg tatgaagaag tcgaaaaaaa
    33001 agacgtgccg aaaacagcac tggaaaaact aattaaaggg tagggaaaga aatgaacaaa
    33061 atagtcgaag tacagaatgt aacaaaagta tacggaaaaa acaatgagaa aaagacgcaa
    33121 gcattaagcg gcatcagctt cgatgtagaa aaaggcgaat ttattgggat catgggcgct
    33181 tctggttctg gtaagtcgac acttttgaat attttatcca cattagataa accaacagat
    33241 gggcatatcc gaatcaatca aaaagatgtg accacattaa aaggaaatca actagcagat
    33301 tttcgtgcga atgagattgg ctttattttc caagatttca atttattaga aagcttgaca
    33361 gcacaagaaa atatcgctgt tcctctttct ttacaaggcg tcagaccaaa agaaatcaag
    33421 caacgtgtcc aaaaaattgc agaacgttta tccatctctc atattttgga aagctatcct
    33481 tctgagattt ccggtggaca aaaacaacgg gtcgccgccg cacgtgcatt gatcacacaa
    33541 ccaacgattc tattagggga tgagcctaca ggtgcgctgg attccaaaag tgcccgggat
    33601 cttttagata cgatggacga attgaataca aaagatcatg tatcgattct tcttgtgacg
    33661 catgatccgt tttctgcaag ttattgccaa cgtattttat tcatcaagga tggcggtatc
    33721 catcaagaag tgaaacgtgg agatcaaagc cgtgattcct tctatcgaga aatactatct
    33781 attcttggaa acttggaaca gtagggggag attgactatg ctttggaaat tatcacttac
    33841 tgggatcaag agccgtttaa gagactactt ggtgttattc tcaggattag ttatggcatc
    33901 tgctattttt tacatgtttg aatcaatggc aagcaacgaa gcttttttga aaagtaatac
    33961 gatcgttgcg gctacagtta tcattttccg attcggttct gttttactag ggatcatcac
    34021 attcgtttat attttatatg caaattcctt tttgatgacg atgcggcaaa aagactatgc
    34081 aatgtttatg atgctgggag caaaaggcag aaaaatcgca cagatgattt tttctgaaac
    34141 attcttagta gggatcgcag ctactttagt gggttcagct gtcggtgtag gattgacaag
    34201 tatcgtccac cgattattag tggatcagtt agatctcaat atttcgcatt ttacaccttt
    34261 tagtattcac gggttgttga tcactgtttt gttttttgct gttttgtttt tattagctgc
    34321 tgttgtcaat gctttttcga ttgtcaaaaa accgatttta gcattgattc gtgcggatca
    34381 gacaccaaca agaatcaagc agcataaatt cttgtttttc cttgaagtag tactgggaat
    34441 tgcttttcta ggctgcggtt actatatgat gaaacacgtg gggacctatc aagtctttgg
    34501 tataggggta gccttagtta cgatcgtatt aggaacttat ttcattttcc attctgtgat
    34561 cattttcttt ttatcattac taaagaaatc agaacagatt tcattgaaaa aattgaacaa
    34621 tttcacattg tcacagttaa actttcgtat tcgtgaatat acacaaatgc tctcaatggt
    34681 cgctatgctg tttgccttgg cactgggcgc tttgacggta ggattaggtt ttaaaaatga
    34741 aattgcagac ttgacagaaa acaattctgg atatgatcta gtgatgaata atcctcgggc
    34801 agaagatcag caaaaaatca aagaactttc accaacactt tctgcttctt atactcaaaa
    34861 agaagatgcg ggaacgattt actataatgc aagtgaattt gcggctcaac cattgatcat
    34921 gataaaacat gaagatggaa caccgccgaa gatcacgaaa gaaaaagttc ctgctaaaaa
    34981 aatgaatgaa ctgactgtac aagaggaact tcgaagctat gaattgccgg aacagcaaga
    35041 aaaagaaatc aaggtagtca gtcaatcaga atttgatcaa ctgaacttgc cacaatccac
    35101 tttacagcta gttcaggtaa aagacttcca agcaaacctg aaaccaatcg aaacacttgt
    35161 tgctcaaaat aaaatgaaca atccatcttt gcaaaaagta gagtacagca accagaaata
    35221 tgaaatgtat gaagtgtata atggtctatt ctctggtttt gaatttatgg gattcttcct
    35281 aggtttagct ttcttgacca tgcttgctag ctgtttgatg ttcaagatct tgtcaggaag
    35341 caagagtgac attgctcgtt atgaaatgct tgaaaagata ggaacacgac gcgggttgct
    35401 taaacaatcg atccgtagag aagtaggcgt gttattctta gcaccaggaa tcttaggtgt
    35461 agtccatgtc ttattcggat tacaaatgtt tggtctattc atgcaaaatc catacaaaga
    35521 tatttgggtt ccgtttacga tattcttcgt attgtatttc atctactatg tactgacgac
    35581 atggttatat actggaatcg tattgaaaaa gagattgtga aaaagctgtc ctgcatcaag
    35641 taataagaac agccaagcaa aaatagctcc tcatattttt cgtttggttg ggcttattac
    35701 cgcagatgca agcttttgaa caccgtttgt tcggaaaaag aggttgtgac aatatttttg
    35761 tcacaacctt tttttcacgg tcttttatta gaatatagta aattttttct cgttactcac
    35821 ggaataagct gttaagaaaa cggtttccat gtatactgga atcagtgcaa atgaaagaaa
    35881 agagggtgca aggaacatgg aaatcaatga acaaaatttt ggcgaaaact atcacttgat
    35941 tacgatcacg aatcaaaatg ggacatcttt gtctgtcagt gatcttgggg cacgggttgt
    36001 tcattttcaa acaataatcg ataatgaaaa acgagagttg atcttaggtt ttgatgaagc
    36061 aaaagaatat ctagaaaaag acccttatat cggtgcttca atcggacgta tggctggacg
    36121 gattacgaat ggcacattca aattagatga tgaaacgttc gaagtaaaaa cagacccgga
    36181 cactggtcat tgtttacatg gtggtgcacc tagctttgaa gccaagcagt ggcattatac
    36241 agtcatcaat ggtgaaaacg aagcatcggt cattttctat cagactagcc cagatatgga
    36301 aaacggattt cctggaactt tagatgtaga agtacggtat acgctgacga acgatgatac
    36361 atggcgagtg acggtccaag ggatcagtga ccgcaaaaca gtattcaatc ctacaaatca
    36421 tgtctatttc aatttaaccg gtgatccagc acagtcaatc gacgaacata tactttggtt
    36481 gaatagccga ttatttgcta cgctcaataa agatacaacg cctacaggag aagtagtttc
    36541 agtaagtggc acagcatttg acttccaacg tcctaaaaaa ttaggtgagg tctttgccag
    36601 tgattttcgc caatcaatga tagtgggcgg catcgatcat ccatttttgt tgaaaaaaca
    36661 atctggttta ctaaatgctg cggaattgac aagcccagat gaaaaagtat cgatccaagt
    36721 aaaaacagat gcttcaggaa tcgtgatttt tacagcaaat tttggagaag atggaccgga
    36781 aatgcgcggg aataaattag taaatcatgg cggtatcaca tttgagactc aagaactgcc
    36841 aggagcggag cgacttgaaa gttttggaga tgtcactctg gaacctaacc aagtacgcga
    36901 gtttgtaacg gaatacaaaa taaatataaa gaaatagaat aaattaaaa
//
LOCUS       DAZKKZ010000024        36847 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.024, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000024 DAZKKZ010000000
VERSION     DAZKKZ010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 36847)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36847)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36847
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.024"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     regulatory      118..197
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01767"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="SMK box riboswitch (SAM-III) riboswitch; SAM
                     riboswitches modulate the expression of downstream genes
                     in response to levels of S-adenosylmethionine; SMK box
                     riboswitch shares no known similarity to SAM-I and SAM-II;
                     Derived by automated computational analysis using gene
                     prediction method: cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF01767"
     gene            195..1388
                     /gene="metK"
                     /locus_tag="ACG8LA_001277"
     CDS             195..1388
                     /gene="metK"
                     /locus_tag="ACG8LA_001277"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004478 - methionine adenosyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006556 - S-adenosylmethionine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HFQ0203583.1"
                     /translation="MVERHLFTSESVSEGHPDKIADQISDAILDAILKQDPTARVACE
                     TSVTTGLVLVFGEISTTAYVDIQKVVRETIKEIGYTRAKFGFDGDTAAVLVAIDEQSP
                     DIAQGVDEALEIRDEDKKDVLDEIGAGDQGLMFGFAVDETPELMPLPIALSHRLVRRL
                     ADLRKSNELTYLRPDAKSQVTVEYDDQGQPERVDTIVISTQHDDAVDNETIRHDVIEK
                     VVKEVIPAELLDDQTKYYINPTGRFVIGGPQGDAGLTGRKIIVDTYGGYARHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLARKAEVQLAYAIGVAQPVSISINTFGTGTVP
                     EEELIAAVRENFDLRPAGIIEMLDLRRPIYKQTAAYGHFGRTDVDLPWEHTDKVDALK
                     ASLAK"
     gene            1518..2990
                     /locus_tag="ACG8LA_001278"
     CDS             1518..2990
                     /locus_tag="ACG8LA_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MDR family MFS transporter"
                     /protein_id="HFQ0203584.1"
                     /translation="MKKETNVTLVTVSIFIATFMTAIEGTIVTTAMPTIVGSLHGMEI
                     MNWVFSIYLLTNAMLTPIYGKLADKVGRKPIFIFGTLLFIIGSLFCGLSQSMIGLIAA
                     RAIQGMGAGAMMPVALTIIGDLYSIEKRAKVLGLNSSAWGIASVFGPLAGGFIVETIS
                     WHWIFFINVPIGILLIILIWLYLNEPKIIHESKPMDIFGSFSLMAMLVSLLLGFQLLG
                     DEGMSPLVSALLLGSIVMLGIFVFAEKRAKDPVIMMHLFKNPLFVVVNLAAALASGFL
                     MGIDVYIPMWMQGVLGLNAAIGGLVLAPLSLVWMVGSFLASKWMTQMKTHWVLRIGLL
                     IAAIGGAWLYLMPFRSNYLWFFAISTVIGIGLGVTMTTSTVSAQNSVSRDQLGVATSF
                     NTLVRTIGQTVMVSIFGLLINGVTKRELAAANLTNDADIMNKLVNPQTAKYIDADILL
                     PLRKILYDGLHSVYLVGLLLVIIALVLTLFVHEKSGKIKQ"
     gene            3073..3861
                     /locus_tag="ACG8LA_001279"
     CDS             3073..3861
                     /locus_tag="ACG8LA_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFQ0203585.1"
                     /translation="MAFIQANIYSNVLEMEVNLNVILPQTTKKVIGTSSEQETTDIPV
                     LYLLHGMGGNHSVWERRTSIERYVANYGLAVIMPSTDLGWYTDTVYDMKYWTFIAEEL
                     PEICHELFPQLTRKREKTYAAGLSMGGYGALKLGLAKSENFAAVISLSGAVSVGNRMD
                     DLLMVRKASFWEGIFGPLDQIEGSKNDPQYLLKELVKSGKPVPRFYMACGESDFLYQA
                     NQEMVSAMQEQGLAVTFEQGPGDHNWIFWDQWIQRALAWLMEEK"
     gene            complement(3928..4596)
                     /locus_tag="ACG8LA_001280"
     CDS             complement(3928..4596)
                     /locus_tag="ACG8LA_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HFQ0203586.1"
                     /translation="MEIKLSQAIIIQAAFDILAETQALSQLSMRNIANRIHVQAPALY
                     WYFKNKQQLLQKMAETMEEELALPDPTLPWNEQLLQYMENYYDLYTRFPCGAELEINT
                     VPAFPSRLEHLEQMIQLLVREGFSVTQSHQAIASLHNLLIGQLMDQQHEQQLRQKIMD
                     GNEFLKETVLFMRNYVVENQLEGFKESMQSHAELNEKALFLTSAQTYIEGLCQQNKRR
                     ENEQ"
     gene            4711..6423
                     /locus_tag="ACG8LA_001281"
     CDS             4711..6423
                     /locus_tag="ACG8LA_001281"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0203587.1"
                     /translation="MKLILRHAKKYKVSVFISLLSVAVMVAAALWQPKLLQQVLEAII
                     TEDNDEMKTIGIYLISLALLGLAAGVTNTIFSAKVAQGVSADIREEAFRKIQTFSFGN
                     IEQFSAGNLVVRLTNDITQIQNLVMISLQSLFRIPFLFIGAFILAMITMPQLWWIIVA
                     LIVTVFLITALSFTRMGKHFMIIQKLIDRVNSIAKENLLGIRVVKSFVQEENQLKSFS
                     KVSEDLTKHNIIVGTLFSVMIPSFMLAANLAVVGAIFFVSDLVKDDPTLIGGIASFMN
                     YLMQIMMAIIIGGMMMMMTSRAAVSLKRIAEILDAEPDLTYLDVPEQELTGSVTFDHV
                     SFRYPGEDTDTLKDISFSIKPGEMVGIVGATGAGKSTLAQLIPRLFDPTEGKVEVGGV
                     DLRQVNEKSLRQTVSFVLQKAILFSGTIAQNLRQGKKNATEKEMEHASSIAQAKEFIE
                     KLSDRYEAPIEERSSNFSGGQKQRLSITRGVIGNPKILILDDSTSALDARSEKLVREA
                     LDRDLKGTTTIVIAQKIASVVKADRILVLDEGRLVGEGTHEELVAGNRVYQEIFETQK
                     GTEE"
     gene            6426..8198
                     /locus_tag="ACG8LA_001282"
     CDS             6426..8198
                     /locus_tag="ACG8LA_001282"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0203588.1"
                     /translation="MTDLIKASKFFYHYLKRYKLSFFFIFITVIIATYLQVKAPQYIG
                     EAFQELANYVGGLMQGVDDKSKFVSVIWKLLLFYVLASAANFIYSILFTQVVGKSTNR
                     MRIGLFNKLEKLTIRFFDSHQDGEILSRFTSDLDNIQNSLNQALLQVITNAVLLVGIL
                     IMMFRQNVELAWATIASTPVAVLIAVLIIRKARKYVDLQQDEVGKLNGYMDEKISGQR
                     VIITNGLQEETIEGFLEHNQSVREATFKGQAYSGLLFPMMQGMSLVNTAIVIFFGGWL
                     ALNGDLERSVALGLVVTFVQYSQQYYQPLMQISSGYSMIQLAITGARRLNEIFDEKDE
                     VKPENGKAFDGVEKGLALQHVDFGYSPEKLVLKDVSINVDKGEMVALVGPTGSGKTTI
                     MNLLNRFYDVNDGSVVIDGIDIRDYDLDALRRHVGIVLQESVLFSGTIKDNITFGKPD
                     ASDEEVINAAKQANIHDFIMTLEKGYDTEISEENNLFSTGQKQLISIARTIITNPSLL
                     ILDEATSNVDTVTEARIQKAMDEAIKGRTSFVIAHRLKTILNADRIVVLRDGEVIEEG
                     SHHELLAENGFYAELYHNQFVFES"
     gene            complement(8280..9401)
                     /locus_tag="ACG8LA_001283"
     CDS             complement(8280..9401)
                     /locus_tag="ACG8LA_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFQ0203589.1"
                     /translation="MWLEKINDKKFKYTERYTDPLTEKKRKVSVTLSSNSRQAWNQAN
                     LLLNEKIAEKIKRNEELPLTFGELKTKWDEKYKPTVKESSYRTTQVYLSLISKYIKDD
                     VLVKNVNSNLIQDMLDYYYFEKNLSYNYVIHLKTFTGMIFKFANRRYGLKYNPVNGVS
                     LARKPKTNEEIKKEKDGYLSKEEVQMIASKQKSSHQQSRYSLITKFLFLTGLRYGELI
                     SLTESDYDGNKITVSGTYDYELKIKTTTKNTGSYRTIELSSNAKEIIDQLIEENKLIK
                     NNKDKYIFISKNGNPISIQAYNQSLRAVSKELNLDKKVSSHMLRHSHISLLTELGIPL
                     KAIMDRVGHEDSKTTLKIYTHTTKNMQNQLVEKLGKIEI"
     gene            complement(9473..10753)
                     /locus_tag="ACG8LA_001284"
     CDS             complement(9473..10753)
                     /locus_tag="ACG8LA_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4041 domain-containing protein"
                     /protein_id="HFQ0203590.1"
                     /translation="MLLLIGLILLIIGNTKLSKANTIKKEAYELEQKNDEKLNKLHDR
                     ERFILSKEETLSDLNKQITMLKNDIILLKKEKEDLNDEINQKYDETLKNVYSSLIVSN
                     IEETSSSEIKNKLSLLKLKEKEYIIDDAVSVPLILNKREKNNLKKKMLIPFDSEVKGL
                     LNKLTISNIDSTREKIIKIFDKINNLFKNDNAELRKGLLEFKLQELELHYSYLVKITE
                     EKEQQKAIKEQMIEEEKVRREIDREKKRIDKEQRQFNSEISKLIAYMQKANADVEKEL
                     YANKIQELEEKLKELEVIRENVLQRELNTRAGYVYVISNIGSFGEDIYKIGMTRRLEP
                     MDRIKELSSASVPFEFDVHAMIFSEDAPSLETKLHNHFRKQEVNKINQRKEFFKVSLD
                     EIEKVVLENYNGTVTFTKLAKAEQYRRSLELSKD"
     gene            complement(10844..11296)
                     /locus_tag="ACG8LA_001285"
     CDS             complement(10844..11296)
                     /locus_tag="ACG8LA_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HFQ0203591.1"
                     /translation="MHLNKYWILEEIEKLFVEFGSDAINPYKIIKYSDIDLIETDLGN
                     KTLGQTIHNKRCYVILINQNLSPSMKRFVLWHEIAHVRLHKGICTAAFRANNLSCMIY
                     GIEAEANMFAIEMLTRTIDEQDLSDMSQFQIIEYLGLPHNLEHLVLQH"
     gene            complement(11309..11719)
                     /locus_tag="ACG8LA_001286"
     CDS             complement(11309..11719)
                     /locus_tag="ACG8LA_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFQ0203592.1"
                     /translation="MLLDRIKILLKERSMTLAELERKLNFGNGSMSRWNKSTPSGDKI
                     QKVADYFNVSTDYLLGRTDKRHYYDLTEKDKQDIALQAEKLLEGLNSDAETNYYGEPL
                     DDEDKEKLYDAIQLALALTKVKAKKKFTPKKYRQ"
     gene            11994..12206
                     /locus_tag="ACG8LA_001287"
     CDS             11994..12206
                     /locus_tag="ACG8LA_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multiprotein-bridging factor 1 family protein"
                     /protein_id="HFQ0203593.1"
                     /translation="MTLKQQVLIALVKKGWSQRELARRMGISITYLRDIFIEKRKPKE
                     RLKQIEELLDIKLEVDSNDQPSEQEA"
     gene            12209..12421
                     /locus_tag="ACG8LA_001288"
     CDS             12209..12421
                     /locus_tag="ACG8LA_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0203594.1"
                     /translation="MVQRLSKAEFKEKYKYSESTYQRRMKEFKKSRFSEGYNAVTSKE
                     ITIDVDLYEQFRTWRSKNRFRVRAVC"
     gene            12561..12716
                     /locus_tag="ACG8LA_001289"
     CDS             12561..12716
                     /locus_tag="ACG8LA_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0203595.1"
                     /translation="MKEESKIGILNENNYTRLIIETEEGKKVAEVTLTDATPADGYRI
                     RLTPKYD"
     gene            complement(12713..12937)
                     /locus_tag="ACG8LA_001290"
     CDS             complement(12713..12937)
                     /locus_tag="ACG8LA_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HFQ0203596.1"
                     /translation="MGKNQHVVPNSNGGWNVKGAGNSKATAHTNTKSEAVKIAREISK
                     NQGSELFIHGRDGKIQSRDSHGNDPHPPKG"
     gene            13015..13203
                     /locus_tag="ACG8LA_001291"
     CDS             13015..13203
                     /locus_tag="ACG8LA_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0203597.1"
                     /translation="MAYTLQQEHQILGLIKQRRKQLQDDRAALRKADELSDRQAELIA
                     SELEDLRMLEIKNREIRL"
     gene            13200..13373
                     /locus_tag="ACG8LA_001292"
     CDS             13200..13373
                     /locus_tag="ACG8LA_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0203598.1"
                     /translation="MKKTDTLFIGFILGLLVIVAHQSIIGGSLFAALMVLINLLDSKE
                     RSNYGTRRSAKNR"
     gene            13342..13470
                     /locus_tag="ACG8LA_001293"
     CDS             13342..13470
                     /locus_tag="ACG8LA_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0203599.1"
                     /translation="MAREEALKIGKVIADNRWGNSRPIILSKQHIEKQKAWQQIKK"
     gene            13529..13864
                     /locus_tag="ACG8LA_001294"
     CDS             13529..13864
                     /locus_tag="ACG8LA_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0203600.1"
                     /translation="MNKKIENLIEELKRECQKQGVSIICTAQKEGELKSLVYGETTEI
                     LLCLAMQEEHLDENLPLSAHIMRRIAVDAYEQAKNEEENQPSNHTFVINNKEDLADVM
                     TRILKGEFQ"
     gene            14097..15038
                     /locus_tag="ACG8LA_001295"
     CDS             14097..15038
                     /locus_tag="ACG8LA_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lambda-exonuclease family protein"
                     /protein_id="HFQ0203601.1"
                     /translation="MSKSTLEMSHQEWLEDRKKGIGGSDVGTILGLNKWKSPYQLWLE
                     KTGQVVLEESGSEPAYWGNVLEEVVAKEFQERTGKKVRRRNQVFEHPLHPFLRANIDR
                     EVVGENAILECKTANQFLGKEWEGEEVPLSYLCQVQHYMNVLNKDYCYIAVLIGGQKF
                     IWKRIERDQELIDTITEQLVEFWETNVLGGIEPIIDGSQATADFLKEKYADVEDVQTT
                     LPIHFDELVEQKNELKRTKKEIESAIRQVDNEIISELGKREASIGITQKNIISWKFVR
                     TRRMNSKKLAEKYPDVANDEEIYNVTESRRLTEREIK"
     gene            15040..15930
                     /locus_tag="ACG8LA_001296"
     CDS             15040..15930
                     /locus_tag="ACG8LA_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecT"
                     /protein_id="HFQ0203602.1"
                     /translation="MATNESLKNQLAAKPQKQVAPGQLGLKALMNTPTMRKKFEEVLH
                     DNANAFMSNVMTLVSNDSYLADSEPMSIMSGALTAATLNLGLDKNLGYAYLVPFNSKN
                     KQTGKWEKKAQFMLGYKGYIQLAQRSGKYKALNVIEVYEGELKSWNRLTEEFEFDPNG
                     RTSDEVIGYVGYFELLNGFKKTVYWTKQEIEAHRIANNKDRDKTKLSGVWASDYNAMA
                     RKTVLRNLLSKWGILSIEMQEATTSDERVQRVQEDGSIIAETEVEEDIPERKEAEVIS
                     EENEDVQTGLFDASNPPLNK"
     gene            15973..16773
                     /locus_tag="ACG8LA_001297"
     CDS             15973..16773
                     /locus_tag="ACG8LA_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HFQ0203603.1"
                     /translation="MNTGYVKLHRKVMNSFVWTNPYMYKLWNLCLMKASHENRKILFN
                     GKEIQVNSGEFVTGRDAITSEMNEGVKREHQVNSGSVWRWLKQFEKNGMLNIKSTTKY
                     SVISIKNWSLYQSSEQQMNIKRTTSEQQVHTNKNEKNYKNEKNNKTSSSQPRKKRVYD
                     TDSVYYILAEELFKQICQNQEIKKPNLQSWADDIRKMIEIDKRTENQVRGMIEWSQHN
                     VFWASNILSAKKLREKYDTMAAQANRDYKTKQTKTLEYEKFSTDELPI"
     gene            16788..17639
                     /locus_tag="ACG8LA_001298"
     CDS             16788..17639
                     /locus_tag="ACG8LA_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFQ0203604.1"
                     /translation="METVGEIMEKLIQKVLVQRGECPECGQPLYGWRTKNPDGSERCK
                     PTCMQCGYKALRVQEDLQTERIYNESLKARAINFFKGGSVVPNQALFDCTLQNYQIVD
                     QETRQAVEVTKRFVNSVLLGNPSHLVLTGKQGTGKSHLAMAAAWEVLKRSNYDKKILF
                     IGLQEMLDQIKFSYNNPELRKTIEGSLIADIKTADLVIIDDIGSELGKDASDSRAFGI
                     NTLNSFLDARQNLATIITTNLLGEELKKAYGTRTISRMFVNSDGFTMVFSQTADKRIK
                     PVKGAIA"
     gene            17840..18301
                     /locus_tag="ACG8LA_001299"
     CDS             17840..18301
                     /locus_tag="ACG8LA_001299"
                     /EC_number="2.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFQ0203605.1"
                     /translation="MPKILDACCGSRLFWFDKNNSDVTFMDCRQQYEELSTGHVINVD
                     PDVVADFRDMPFEDDVFDMVVFDPPHLRHVGENSWLAKKYGKLDELWPEDIRQGFAEC
                     MRVLRPSGTLIFKWNEEQIPLSDVLEAIGEQPLFGNKRSKTHWLVFMKKFS"
     gene            18327..18779
                     /locus_tag="ACG8LA_001300"
     CDS             18327..18779
                     /locus_tag="ACG8LA_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010756066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0203606.1"
                     /translation="MKIVLNKCFGGFGLSHEAKMEIFKRKNIEVFPYINNFSYDSDDE
                     YTRYTGQKLGSMDFIYYFKKDPKIDKVTGIYSEIDRLYGIADDSSFSSDSNRGDKDLV
                     AVVEKLGSEASGPYASLKVVDIPDGAEWEISDYDGVETAHYGFQTGSI"
     gene            18885..19079
                     /locus_tag="ACG8LA_001301"
     CDS             18885..19079
                     /locus_tag="ACG8LA_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0203607.1"
                     /translation="MDASEVVNKINSLKEVFGDVEVVINAQGYDNEFFKQITDISIQQ
                     GMEDEDGNFIDEVAILVTCE"
     gene            19110..19403
                     /locus_tag="ACG8LA_001302"
     CDS             19110..19403
                     /locus_tag="ACG8LA_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0203608.1"
                     /translation="MKLKDGFYSSGHGIGGLMLDMPTKNPKTRKKPKFKVGDMVRCEA
                     EGFIYPFRGYVEHVYNHSAIIRIENTMECDKWLAKSKENLAVVRLVDMEVIKS"
     gene            19334..19873
                     /locus_tag="ACG8LA_001303"
     CDS             19334..19873
                     /locus_tag="ACG8LA_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ArpU family phage packaging/lysis
                     transcriptional regulator"
                     /protein_id="HFQ0203609.1"
                     /translation="MVSEKQREFSSGEIGGHGSYKILILLFYNYPTTMSVIPQLEGEE
                     AIVNILENIDIKQTRKNARRLLKRYRNLERLVGPVKIDFSVMTVTKNLKFTIDSQNEE
                     IIEAISTRDSVIEALTRLSRIHFQVLYYSYCFPNKMSMYQIGEKLGYSDRTIERMKAV
                     ALVEFAEAYKSGELISRTK"
     gene            19948..20415
                     /locus_tag="ACG8LA_001304"
     CDS             19948..20415
                     /locus_tag="ACG8LA_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArpU family transcriptional regulator"
                     /protein_id="HFQ0203610.1"
                     /translation="MVLFDVKKYETPSAKDVDMERTKHNVAVFLSAYLSARCRVGQHR
                     EPKVTASYSLVPPSTADHIFEAERMLIDKEEAQEEFEYLHKLFVRGYSAIQHPHKPDV
                     TERRKKIFYDRYINGLPIYVTAQRNNTSEESVKVESNRIIIQFASSLELVAFK"
     gene            21162..21392
                     /locus_tag="ACG8LA_001305"
     CDS             21162..21392
                     /locus_tag="ACG8LA_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0203611.1"
                     /translation="MRNYWYVSLTNEYPRTIDDCSVRVVRSVQIKGKYSIVEMGREAE
                     PCEIDACKLVYCGHGFYDEPNIQNNINKNLRD"
     gene            21551..22384
                     /gene="terS"
                     /locus_tag="ACG8LA_001306"
     CDS             21551..22384
                     /gene="terS"
                     /locus_tag="ACG8LA_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase small subunit"
                     /protein_id="HFQ0203612.1"
                     /translation="MARQRDPRRDEAKRIWLESNGEKQLKEIASELNVSDSQVRKWKS
                     QDKWSAELISNVTNGKSNVTNQGGAPIGNQNAKGNKGNSRASPPVGNKNALKTGEYET
                     IFFDTLTDNEKDIYSSLNDDPSFALSEEIRLLKIRQLRMMKRIQQAEAGLNDEEVERL
                     QQLRKIKTPIEKNGKKLEIKREVMQDVQISRKKHRKIDDILSIEDSLTRISNQLAKAI
                     KQMNELYMNEYRTDLIKAQTDKIQAETNEIGGNNSGEEIEEWKQAVLNAANKRAVKEN
                     E"
     gene            22377..23792
                     /locus_tag="ACG8LA_001307"
     CDS             22377..23792
                     /locus_tag="ACG8LA_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HFQ0203613.1"
                     /translation="MNNEFIPFADIGSAIDYYYDKPVAFCQDILHLNPDEWQENVLND
                     LAEFSKVSVRSGQGVGKTALEAGAILWFLTCRPYAKVIATAPTMKQLYDVLWAEVAKW
                     LNDSLIKNLLKWTKTKIYMVGDSERWFATARTATKPESMQGFHEDHMLIVVDEASGVS
                     DPIMEAILGTLSGFDNKLLMCGNPNNIEGVFYDSHNSDRDKYRVHKVSSYDSKRTNKD
                     NIEMILKKYGKESDVARVRIFGEFPKGALDSFISLETVELATEKQISDSLVNKTKVAH
                     IGVDVARYGDDSTILFPRIATRALEYEKYSKRSTMETTGYVINMAKNLMSQYPSIDKV
                     MIKVDDTGVGGGVTDRLEELIEDKHYPFEVFGVNNGSTSEDDFYDNLGTQLWGNIKEM
                     LEENMTANLNGEQPVIELPSDSSLIKELSTRKFKMTSRSRIRLESKDDMKKRNIGSPD
                     IADALALAFYEPPSHYQFIQF"
     gene            23804..25333
                     /locus_tag="ACG8LA_001308"
     CDS             23804..25333
                     /locus_tag="ACG8LA_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HFQ0203614.1"
                     /translation="MISTVLSLERYKKLRVKYATQIEDGMFDPNGFIEDMKPFFADRE
                     RKYLAYTSEKNEIDNRPKPNTDIVKVNNKLHAGMYSIVVDQAVNHFTGIPIKWDYDVS
                     EQKRTLIQRLKDKFLKNDIELPTVPEAFNKLTSNLDSMRFAMLDSETATFQGACGVAF
                     RLLEPVEEDDGWKLRASNIEPWRAERYGNAGIYIKEKYDSYQKKFFQEMKVMTRNKIL
                     TYACYGDLNFVTSGTFKKIDETDNPLGTITLAEFKNNTNRYCDFEVAEEIGDAIDRAL
                     SDQQNEIEQFKLAYMLVTGTTMSKGTAKEMMNQLGIINLKAPTAKAEYVTKNLAKDFN
                     EYHMDLLKKQFYTICKAIDFNDEVFKSNSSGEARKWQIISLEAKTNTKEQYFREGLKE
                     CAETIAAFLKFHDKVEIEPEKIIFTFSRSLPTDLSYLAEALPKLAPYVSKRTIQSQIP
                     FVTDVDYENEMMELESGSAYPDSEYNFGGGGNSDDRNEVLDQTSRTGGSSKAQTRKSD
                     T"
     gene            25251..26303
                     /locus_tag="ACG8LA_001309"
     CDS             25251..26303
                     /locus_tag="ACG8LA_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HFQ0203615.1"
                     /translation="MTIETKYWTKRRELEDQARLKQENQTLKKLTSVFPEALKEIQAK
                     LLSQADLHNITYPEMMEFYSTSNQKKYREYVEKNYKSLKMYDAKYKEFIDEFFPPFDY
                     AKVNRLLQIRSDVFKILAEYAMDADVNQYFSDRLEEILQRTYSSNANVFVQLLNVDIP
                     NYLPENEIKHYLNYPWSGKTFSRRLWGNISSLEQKLSNAIVKSVASGEGVIHALNTMR
                     LDSEICDMFKLEESKYNKAIENLVRTEYAKFAQDGIEKSYLETGIEEYNVLTAKDERV
                     CRICGGKASKNPYKLKDAVIGENRAPFHSRCRCTDVPNLPKLGKDIDEEYDRLFGDLL
                     DEFAHDSFGINLKRRK"
     gene            26305..26622
                     /locus_tag="ACG8LA_001310"
     CDS             26305..26622
                     /locus_tag="ACG8LA_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0203616.1"
                     /translation="MKDFFEAVLTINVNADIAEAYKTAIESENHPNGLRDHWNGNYAY
                     VVIGDQTVNYQDNTPVDKNTVNLTIQLLSHSLPNLKETVDWYEKMGCIVVRTDYKEGK
                     SSN"
     gene            26749..27372
                     /locus_tag="ACG8LA_001311"
     CDS             26749..27372
                     /locus_tag="ACG8LA_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HFQ0203617.1"
                     /translation="MSMKHKSLMPMNLQYFAEGDDQKFSFDDFKSFVESNEEAQKFIQ
                     SQSQSVADKQLEAWKQNNLDKIKQDTIKEYEESKKNKSPEQIQLEKLQAEFEAEKALR
                     VTSDNKAFVAEQIAGLELDGELKESISQFMLNNLVSSDTDFTKNAVEGFTSVLNAINE
                     KHADALKELQMKSAFGGTQQSNNQVQQNNETLTNPEEQLGQILQQFN"
     gene            27387..28277
                     /locus_tag="ACG8LA_001312"
     CDS             27387..28277
                     /locus_tag="ACG8LA_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5309 family protein"
                     /protein_id="HFQ0203618.1"
                     /translation="MKKTSLNNLEYLDISPAINAMQVPNTPFLSYLLGAGKTEPANST
                     EIKWREYDINNDDSSEKLEGGEYPDAESGRTWFNNYTEIFRKSTSVSGTLDAINVNGV
                     GNELTNQVALRGMEMKIDLNRKLITGVKADENGSKGRRMNGILNLINSANKAETATAG
                     AVTRKDIDTLFKLMYEKGYMGEKLCLISPDMQELMTDELDGKSTKIVQFGERVTFGLQ
                     IGNIVSNYGTGIALLEPSLPKGTIAAIDTNYVKLRPLREWRAEELAKTTDSRRIGLVG
                     EYSLEYNASNSGAILNLKSE"
     gene            28300..28515
                     /locus_tag="ACG8LA_001313"
     CDS             28300..28515
                     /locus_tag="ACG8LA_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0203619.1"
                     /translation="MIGGITVVKKDETKKDEVVKYRVGKTKNFVGFVHPKTRRFITAD
                     SNNEFIISIDDKEAIAILEDAIDVNEI"
     gene            28527..28868
                     /locus_tag="ACG8LA_001314"
     CDS             28527..28868
                     /locus_tag="ACG8LA_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0203620.1"
                     /translation="MDESLKTEIIESTKEDFPDLSEERITNLLEIILLEIESYNTCKN
                     DISWEKLKSVISEVLYKIIKNESEKTVSSVRRGDTTISYASTTNDVSELLLGYGDLIR
                     RVIGCGGLEFF"
     gene            28868..29239
                     /locus_tag="ACG8LA_001315"
     CDS             28868..29239
                     /locus_tag="ACG8LA_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0203621.1"
                     /translation="MNEADILETTYEDSCIIERLTDIEDSNTNITIQDYKKVYDNPIS
                     CALSQGQIDGLAVIEDGEMVNVSTDTYKLFVHPKIKLKKGDRITITQKASGLIFSLFA
                     TKPFYYPSHCEVNLIGSEKNG"
     gene            29232..29627
                     /locus_tag="ACG8LA_001316"
     CDS             29232..29627
                     /locus_tag="ACG8LA_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HFQ0203622.1"
                     /translation="MGNLKYESNAEKIIENFKNMTVIAQKEGISFVNDSMNKVVSLAK
                     PLTPVKSGNLRRGYRVVKARKLSSGRIVGEVINNEHYFKYVEEGHRTKNGGFVKGKFM
                     LTRATNLANMSYIPRRFKQMAIKIVKKGK"
     gene            29629..30006
                     /locus_tag="ACG8LA_001317"
     CDS             29629..30006
                     /locus_tag="ACG8LA_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6838 family protein"
                     /protein_id="HFQ0203623.1"
                     /translation="MKDEIIAAISSKLKEIYPDGTIYLDSVMQSTKDFYFVLSVMESG
                     TENVGIDIQNVSFLIDIALIDNNPNRNLINELVSRCGTFFNTITIDEQILFPKAYLPD
                     EADGVQHIRFTLEFPQYIEWSER"
     gene            30007..30615
                     /locus_tag="ACG8LA_001318"
     CDS             30007..30615
                     /locus_tag="ACG8LA_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="major tail protein"
                     /protein_id="HFQ0203624.1"
                     /translation="MGEKRSKTGIISVEKPTWFPLEDETGNFPVYGTALPMGTAVSIK
                     PTANYETTQDYGDSVVQDQFTAFGGAEVELEANGYTHKVLSTITGGKIVKGGALRSGE
                     DIAQDGAFAYRRKKSNGKYRYTVFYKGQFALDSDETSTIEGSKVSFTHPTWKGSFVDV
                     PGLGYMYSVDEDDEGVDKAMIGNWFTKVAIPIEEAELSGGTE"
     gene            30615..30956
                     /locus_tag="ACG8LA_001319"
     CDS             30615..30956
                     /locus_tag="ACG8LA_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0203625.1"
                     /translation="MSKYQTTIKLTKKDEEGKYEQVQFKSAEFLPGTVVEDAAGVMEE
                     MQTATDKQSVKKALSRAYSFIADTLFEGQFTGEDYCKGIDAREIASLTGKLLKSVTAG
                     FDETYTETKKK"
     gene            31198..33987
                     /locus_tag="ACG8LA_001320"
     CDS             31198..33987
                     /locus_tag="ACG8LA_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HFQ0203626.1"
                     /translation="MILDESGFTAGMNNAVKKLNSFDETIERKSRNSGSSLGSIWKIF
                     AGSFLASGVTRIVGAGFDLIKGSISGAVDRVDTMNNALRNFQNMGFSNSEIMKNIGKN
                     GLLSQGIQGLPTALNDAISHVQLLASSTGDLTRSTQIFKALNDGILGFGGSTDQVNEA
                     VIQLSQSFSNGKVDAQTWNSMINAQLGPTLSAIAKKMGITMGDLKEGLSQGKISVEEF
                     QNQLIEMDTKGGGGLKSLSQIAKDSTKGIKTSIQNAKTAVTRGVGEVIEGLNKALVDS
                     DLGGFKGIIDKVGSSMESFLKVIAANIPTAVSFLSNLFNEIQKFGSALKFMMPFLVPA
                     ATAFGAFMFQLKGIPAIIKSFNNFKNAIIGVGNSLKIMGAIAAANPFVLIIGAVVGAI
                     AVFGYFMATNEELRNKVISIWNDVKDSVIGVLKNIKDWGIDTWNSAKEMASNAVEGVK
                     DAWSGTKEWFSNTWKGIKDGATGLFDKTVETSRNAVDSVKNAWSNMKKWFSDTWQSIK
                     DSAREKWNGIKGSIMSVAGPLITGIKNAFLHVTFYLETLWNNLVEIGKNVFEILKNVI
                     LAPVLFITSMISGGWEETKNNMIAVWNNIKESAINIWESIKNIFVSYFTNIYFAALNI
                     WTGFKLTLINIWNEVVNQAKSIWLNIKYFFINLWIDIKYFAIQKWIELKFSIIQTWID
                     LKYNAITTWNNIKQFFKDTWKNIKDTAYNTWISIKNTMINTWNNIKDSFWNIVTGIVN
                     SAENAWTNLKNGVSNAINRVKEIFNSLREVNLFEIGKNIIDGLINGVKEKWNALKDTI
                     KGIAGNIKNWIKGALDIHSPSRWMRDMVGKNIVQGIIVGIDKEQSKLDQTMTNLVKTP
                     SVQPVVNGISHLPITQTKQNISASETKEIHLHLNVYGDLPDSMVRKITTKIKTELTRQ
                     MKRDAGAVGGTLYAT"
     gene            33977..34717
                     /locus_tag="ACG8LA_001321"
     CDS             33977..34717
                     /locus_tag="ACG8LA_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HFQ0203627.1"
                     /translation="MQLKRGQFFINQHYSSEFNVYIQNRPASVSASRVIELREREGND
                     SIIIDKGYYKNVTRKIECYYKAPSIDMVQEWEDRITEWLDMSSYSDFILYYDEQYIYQ
                     AVVIEGPEFKGTRKTGNIVPFEFTVSIRPFKENYNGRFTIRQTETFEIYNPEKYSSKP
                     LIKLSGSGDASFYINKDKYDLKSLDRELFIDSKLEEAYRKLDGNLEHQDQVTLFLDFP
                     FLYPGKNEIKWTKNIHSFEIMPRWWRKV"
     gene            34714..>36847
                     /locus_tag="ACG8LA_001322"
     CDS             34714..>36847
                     /locus_tag="ACG8LA_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail spike protein"
                     /protein_id="HFQ0203628.1"
                     /translation="MKPRIYSPTETDFSTNGLGILKDCTRCGIYEVANGKYELELDYP
                     LGTRFDEYFENDYQIKAKPNDQEEYHIFFIDDKDIDTFLNTVTIYAQSRTNRLGRRVV
                     TLVEVDSKTGQEAISIIETKMDKKSDIRLYSDITAVSSTIFEARNVLNCIAGEQGSLL
                     QYWGGEIKREPFKLSLLKRRGRNNVGTIRYGKDMSGLKVKLDWTGIKTRIIPYADPQS
                     EVGTTNRIYGSPVDSAYINNYPDVYTEHVQFTEEQGVKDIKSLNKIAKNYFKTINPGC
                     DKPKVSITVEFDKLTDSEEAKEFAKIRNYGLFDTFKIYHKKYNIYLESKVSGLQYDSL
                     SEKTLKLEAGDIQVAFYQQQAVTIQDKLKDYATNNYMSDFNDYVSSMITGQGSAGGYV
                     VLWPKEKPSNIFIMDNPDLEKAREVLRMNKNGIAFSKKGWRGPFNSAWTLDSIFNANF
                     IQTGLIKADIFQNSFNKTGDVLKLVNGLLQIWNNKKKIMELTKKGMEFWNSKGSIGTI
                     GTTDSVGNPFPGASTPTPIEDNSLVIRTNGDGKYILISPKVGKGLVLLGNGKAIYFGD
                     LDVQGKLTVKGKEIIPGQGGGPSGGGESTGGYPSELKTDAEKRAWRIYDILCNNGFTK
                     QSACGILGNIQQETGGTFDPDTVQIGGPAYGLVQWDGSSYPLVGPATWDGKVYVQNLF
                     NAAGIKEPITSLDAQVRLLIWTFTNGQWM"
BASE COUNT        12679 a         5487 c         7437 g        11244 t
ORIGIN      
        1 ctttatggat gattgtgcta agcttttttg gacagttcta atgtaaaata tttttatatt
       61 ttttaagcaa aaaaatgaaa aaatacgagc agaaaactgt tttatctgct atacttggtt
      121 cgttgcaagt tcccgaaagg atccgcagga cggagatgcc ttgtaaccga atttaactag
      181 ggggaatcat tataatggta gaaagacact tatttacatc agaatctgtt tctgaaggac
      241 atccagataa aattgctgac caaatcagtg atgcaatctt ggatgcaatt ttaaaacaag
      301 atccaacagc acgagtagcg tgtgaaacgt ctgtaacaac tggtcttgtt ttagtatttg
      361 gagaaatatc tacgacggca tatgtagata ttcaaaaagt cgtacgggaa acaataaaag
      421 aaattggtta tacacgtgca aaattcggat ttgatggaga tacagcagct gtattggttg
      481 cgattgatga acaatctcct gatattgctc aaggagttga tgaagcactt gagatccggg
      541 atgaagataa aaaagacgta ttagatgaga ttggtgctgg tgaccaaggt ttaatgtttg
      601 ggtttgctgt agatgaaaca ccagaattga tgcctttacc aatcgctttg agtcatcgtc
      661 tggtacgacg cttggcagat ttgcgtaaat caaatgaatt aacgtattta cgtccagatg
      721 caaaatctca agtaacggtt gaatatgatg atcaaggaca accggaacgc gtagatacaa
      781 tcgttatttc aacacagcat gatgatgcag tagataatga aacaattcgt catgatgtca
      841 tcgaaaaagt agtgaaggaa gttattccag ctgaattatt agatgatcaa acgaaatatt
      901 atatcaatcc gactggccga tttgtcattg gtggtcctca aggggatgcc ggattaacag
      961 gaagaaaaat cattgttgat acgtatggcg gttatgctcg tcatggtggc ggtgcttttt
     1021 ctggtaaaga tgcgacaaaa gttgaccgtt ctgccagcta tgctgcacgt tatattgcta
     1081 aaaacattgt tgcagcaggg cttgctcgca aagcagaagt acagctagct tatgcgattg
     1141 gtgttgctca acctgtttcg atctcaatca atactttcgg tactggaacg gttccggaag
     1201 aagaactgat tgctgcagtg agagaaaact tcgatcttcg gccagcagga atcatcgaga
     1261 tgcttgattt gcgtcgtccg atttacaaac aaacagctgc ttacggtcat tttggtcgta
     1321 cagatgtaga tttgccttgg gaacatacgg acaaagtaga tgcgttgaaa gcaagtttag
     1381 caaaataagt tatattcagc tggaacgatc gccaagtggt ggttgttcca gcttttttta
     1441 tggcagttaa cctcttgaaa aagatagtaa ttatttatct atttttagat cctgtcataa
     1501 tgaaagggag gaataagatg aaaaaagaaa caaatgttac tttggtcaca gtgagtattt
     1561 tcattgcaac gttcatgacg gctattgaag gtacaatcgt aacaaccgct atgccaacga
     1621 ttgtcggttc attacatgga atggaaatca tgaactgggt attttcgatt tatttgctga
     1681 caaacgctat gcttactccg atttacggaa aacttgcgga taaagtggga cggaaaccaa
     1741 tctttatttt tgggacatta ttgtttatta tcggttcgtt attttgcggt ttatctcaaa
     1801 gcatgattgg gttgattgct gctcgtgcga ttcaagggat gggtgctggg gcaatgatgc
     1861 cagtagcttt gacgatcatc ggcgatcttt attctattga aaagcgagca aaagttttag
     1921 gtttgaatag ttcagcctgg gggattgcca gtgtttttgg accgcttgcg ggaggattca
     1981 tcgttgaaac gatcagctgg cactggatct tttttatcaa tgtgccgatc ggaattctat
     2041 taattatttt gatttggcta tatttaaatg aaccaaaaat catacatgag tctaaaccaa
     2101 tggatatttt tggtagtttt agtttgatgg ccatgcttgt ctcattgctg ttagggttcc
     2161 aattattagg agacgaagga atgagtccgc ttgtttctgc tttgctgcta ggtagtatcg
     2221 taatgttagg tatttttgtt tttgccgaaa aaagagctaa agatcctgtc atcatgatgc
     2281 atttattcaa aaatccacta tttgttgtgg tcaacttggc tgcagcattg gctagtggtt
     2341 ttttgatggg aatcgatgtt tatatcccta tgtggatgca aggtgtatta gggctgaatg
     2401 cagcaattgg tgggctggta ttagcaccat tatcactagt ctggatggtc ggttctttcc
     2461 ttgcaagcaa gtggatgact caaatgaaaa ctcattgggt cttgagaatt ggactactaa
     2521 tcgcagctat tgggggcgct tggttgtatc ttatgccttt cagaagtaac tatttatggt
     2581 tttttgctat atcaacggtc atcggtatag gcttaggtgt gaccatgact acctcgactg
     2641 tcagtgcaca aaatagtgta tctcgtgacc agcttggtgt agcaacttct tttaatacgt
     2701 tagttcgaac aattggtcaa acagtcatgg tttctatttt tggtttattg ataaatgggg
     2761 taactaaacg agaacttgca gcagcaaatt taacaaatga tgcagatatc atgaataaac
     2821 tggtgaatcc acaaacggct aaatatattg atgcggatat tttgttacca ttaagaaaaa
     2881 ttctttatga tgggttacat tccgtttatc tagttggctt gttactcgtg atcattgctt
     2941 tggtcttaac gcttttcgtt catgaaaaaa gtggtaaaat aaaacagtag tttcggttaa
     3001 gatatgtacg tagccgaatc attcaaattt aaagttattc aaaaataact tcttactaag
     3061 gaaggcgaaa atatggcatt tattcaagca aatatttatt cgaatgtgtt agaaatggaa
     3121 gtcaatctaa atgtgatact accgcaaaca acaaaaaagg tgattggcac cagttcagag
     3181 caagagacaa cggatatacc tgttttatat ttacttcatg gaatgggtgg caatcatagt
     3241 gtatgggaaa gacgtacgtc gattgaacgt tatgtagcaa actacggatt agctgtcatc
     3301 atgccatcta ctgatcttgg ctggtacaca gatacagttt atgacatgaa gtattggaca
     3361 ttcattgcag aagagctacc tgagatttgt catgaattat tcccgcaatt aacaagaaaa
     3421 agagaaaaaa catatgccgc tggattatcg atgggcggat atggcgcgtt aaaactaggc
     3481 cttgcaaaat cagaaaattt cgcagcagta atctctcttt caggcgctgt ttctgtagga
     3541 aatcgaatgg atgatctttt gatggttcgt aaagcatctt tttgggaagg gatctttgga
     3601 ccattggatc aaatcgaagg ttcaaaaaat gatccgcaat acttattgaa agaactagta
     3661 aaaagcggaa aaccagttcc aagattttat atggcttgtg gggaatctga ttttctttat
     3721 caggcaaatc aggaaatggt atctgctatg caggaacaag gcttggcggt cacctttgaa
     3781 caaggacctg gcgatcataa ctggatcttc tgggaccaat ggattcaacg tgcattggcg
     3841 tggctaatgg aagaaaaata aaaaaagagt cttaaaaaga tagctcctat agagatcaca
     3901 aacatagtga tctctatagg agctttttta ctgctcgttt tctcttcttt tattttgttg
     3961 gcataagcct tcaatatagg tttgtgcact cgttagaaag agtgcttttt cattcaattc
     4021 tgcatgggac tgcatacttt ctttaaatcc ctctaattga ttttcaacta cataattacg
     4081 cataaataga actgtttctt tcaaaaattc atttccgtcc ataatttttt gtcgaagctg
     4141 ctgttcatgc tgctgatcca ttaactgtcc aatcaataaa ttgtggagag aggcaatggc
     4201 ctgatgactt tgggtgactg aaaatccttc acgaacaagt aattggatca tttgctccaa
     4261 atgttctaat cgactcggaa aagcgggcac agtattgatt tctaattctg ccccacaagg
     4321 gaaacgtgta taaaggtcat agtaattttc catatactgc agcaactgtt cattccaagg
     4381 caaagttgga tctggaagcg ctaattcttc ttccattgtt tcagccattt tttgcaagag
     4441 ctgttgtttg tttttgaaat accaatataa agcaggtgct tgaacatgaa ttctgtttgc
     4501 gatgtttcgc atggaaagct gcgaaagagc ttgtgtttca gccaggatat caaaggcggc
     4561 ctgaatgatg attgcttgag aaagctttat ttccatttta tcaacctcgt gtattgcatt
     4621 atctttttaa acatggtaaa ttgttagtcg gtctaatttt acagtgttaa attagtcctg
     4681 tcaatttaaa caaaggggtg taatcaacga atgaaattaa tcttacgaca tgcgaaaaaa
     4741 tataaagtat ctgtttttat ttccttgctg tccgtagcag tcatggttgc agcagcatta
     4801 tggcaaccta agttactaca gcaagtattg gaagctatta ttacagaaga taatgatgaa
     4861 atgaaaacaa ttggtattta cctgatcagt ctggctttgc taggattagc cgcaggtgta
     4921 acgaacacga ttttctctgc aaaagtagct caaggcgtaa gtgcagatat ccgagaagaa
     4981 gcatttcgaa agatccagac attttcattt ggaaatatcg aacagttctc tgctggaaat
     5041 cttgttgttc gtctaacaaa tgatatcacg caaatccaaa atttagtgat gatttctttg
     5101 caatcacttt ttcgaattcc attcttattt attggtgcct tcattttagc tatgatcacg
     5161 atgccgcaat tatggtggat catcgtagcg cttatcgtta cggtatttct gattacggca
     5221 ctttcattta caaggatggg caagcacttc atgatcattc aaaaactgat tgatcgtgtg
     5281 aatagcattg caaaagaaaa cttactaggg attcgtgtag tgaaatcttt tgtacaagaa
     5341 gaaaaccaat tgaagtcatt cagcaaagta agtgaggact taacaaaaca caacatcata
     5401 gtcggtacat tattttctgt gatgatcccg tccttcatgc tggctgccaa tttggctgtg
     5461 gttggggcga tcttttttgt gagcgatctt gttaaagatg atcctacgtt aattggtgga
     5521 attgcttcat tcatgaacta cttgatgcag attatgatgg caatcattat tggcggaatg
     5581 atgatgatga tgacttcaag agcagccgta tcgctgaagc ggattgcgga aattttagat
     5641 gctgaaccag atcttactta tttagacgtt ccagaacaag agttgacggg ttctgtcact
     5701 tttgaccatg tttcttttcg ttatcctggt gaggatacag atacgcttaa agatatcagc
     5761 ttttctatca aacctggaga aatggttggt atcgtcgggg cgactggtgc cgggaagtca
     5821 acactagcac aattgatccc tcgtctattt gatccgacag aaggcaaagt tgaagtaggt
     5881 ggtgtagatc ttcgtcaagt aaatgaaaag agtttaagac aaacggtttc ctttgttttg
     5941 caaaaagcaa ttttattctc aggaacgatt gctcaaaact tgcgccaagg gaaaaagaat
     6001 gcaacagaaa aagagatgga acatgcttct tctattgctc aagcaaaaga attcatcgaa
     6061 aagttatctg atcgttacga agcaccaata gaagaacgta gcagtaactt ttctggtggt
     6121 caaaagcaac gtttatccat tactcgtggc gttatcggta atccaaagat cttgatccta
     6181 gatgacagta cgagtgcact ggatgctcgc tctgaaaagc tggtccgaga agcactcgat
     6241 cgagatttga agggaacaac gacgattgtc atcgcacaaa aaattgcttc tgttgtcaaa
     6301 gcagaccgca tcttagtatt ggatgaaggc agattagtcg gcgaaggaac ccatgaggaa
     6361 ttggtagctg gaaaccgtgt ctatcaggaa atctttgaaa ctcaaaaagg aacggaggag
     6421 taagtatgac tgatctaata aaagcaagta aatttttcta tcactatttg aagcggtaca
     6481 aactctcctt tttctttatc tttatcacag tgatcattgc tacctatcta caagtaaagg
     6541 cacctcaata catcggggaa gcttttcaag aattagctaa ttacgtagga ggcttgatgc
     6601 aaggcgtaga cgataaaagc aaatttgttt ctgtaatatg gaaactcttg ctgttttatg
     6661 tactagctag tgcagccaac tttatctata gtattttgtt cacacaagta gtagggaagt
     6721 caacgaaccg aatgcgtatc ggtctattca acaaattgga aaaattgacg atccgtttct
     6781 ttgattctca tcaagacggt gaaattttaa gtcgttttac cagtgactta gataatattc
     6841 aaaatagttt gaaccaagct ttgcttcaag tcatcacgaa tgctgtttta cttgtcggga
     6901 tcttgatcat gatgttccgc caaaatgtag agttagcttg ggctacaatt gcttccactc
     6961 cagtagccgt tttgatagct gtcttgatta tccgcaaagc acggaaatat gtggatcttc
     7021 agcaagatga agtggggaaa ctaaatggtt atatggatga aaaaatcagc ggacaacgtg
     7081 tcatcatcac aaatggctta caagaagaaa cgattgaagg attcttagag cataatcaaa
     7141 gtgttcgcga agcaaccttc aaaggacaag cttattctgg tctactattt ccgatgatgc
     7201 aaggaatgtc actggtcaat acagcgatag ttatcttttt cggcggctgg ttagcattaa
     7261 atggtgattt ggaacgttcg gtggcattag gcttagttgt gacattcgtc cagtattcac
     7321 aacaatatta ccaaccactg atgcagattt catctggata cagcatgatc caattagcga
     7381 ttacaggggc aagacgattg aatgaaatat ttgatgaaaa agatgaagtc aaaccagaaa
     7441 acggtaaagc atttgatggt gttgaaaaag gtcttgcgtt gcagcacgta gattttggtt
     7501 attctccaga aaaactagtc ttgaaagatg tctcgatcaa tgtggacaaa ggagaaatgg
     7561 ttgctcttgt tggtccaaca ggatcgggga aaacgacgat catgaatctg ctaaaccgtt
     7621 tttacgatgt caatgatggt tcagtagtca tcgatggaat agatatccga gattatgatc
     7681 ttgatgcatt acgtagacat gtaggaatcg ttttgcaaga atctgtattg ttctccggaa
     7741 cgatcaaaga caatatcaca ttcggcaaac cggacgcttc agatgaagaa gtcatcaatg
     7801 cagcaaaaca agcgaatatt catgacttca tcatgacgtt agaaaaaggt tatgatacag
     7861 agatatccga agaaaataac ttattcagta caggtcaaaa gcagttgatc agtattgctc
     7921 gaacgatcat cacaaatcca tctttattga ttttggatga agcaacaagt aatgtagaca
     7981 cggtaacaga agcaaggatc caaaaagcaa tggatgaagc aatcaaagga agaaccagct
     8041 ttgtgattgc tcaccggctg aaaacaatct tgaatgcaga tagaatcgtt gtcttgcgtg
     8101 atggggaagt cattgaagaa ggcagtcatc atgagttatt agcagaaaat ggattttatg
     8161 cggaacttta tcataatcaa tttgtatttg aaagttaaat taaaagaacc tcgttataac
     8221 ggggttcttt ttatatattt tatgttgttt gtttttataa ggggcagaaa aggggcaatt
     8281 taaatttcta tttttcctag tttttctact agttgatttt gcatattttt agttgtatga
     8341 gtataaatct ttaatgttgt ttttgaatct tcatgtccta cacgatccat aatggctttt
     8401 aatgggattc ctaattctgt aagtagagaa atgtgggaat gccttaacat gtgagaagaa
     8461 acttttttat ctaggtttaa ttctttggat actgctctta aagattgatt atatgcttga
     8521 atagatatcg ggttaccatt tttagagatg aaaatgtatt tatctttatt attcttaatt
     8581 aatttgtttt cttcaattaa ttgatctatg atttctttag cattacttga taattcaatg
     8641 gttctataag aacctgtatt tttagttgtt gttttaattt ttaactcgta atcataagta
     8701 ccagaaaccg taattttatt accatcataa tcagattcag tcaaagatat caattcacca
     8761 taacgtagtc cagttaaaaa caaaaattta gtaattaaag aataacgtga ctgttgatgt
     8821 gaactttttt gtttactagc aatcatttga acttcttctt ttgataaata accatctttt
     8881 tcttttttta tttcttcgtt tgtcttaggt tttcttgcta aagaaacccc atttacggga
     8941 ttatatttta atccatatcg acggttggcg aatttaaaaa tcattcctgt aaaagttttt
     9001 aaatgtatta cataattata tgataaattt ttttcaaaat agtagtaatc tagcatatct
     9061 tgtataagat tactattaac gttttttaca agtacatcat cttttatata ttttgaaatt
     9121 aatgatagat aaacctgagt tgttcgatag gaactttctt ttacagttgg cttgtatttt
     9181 tcatcccatt tagtttttaa ttctccaaaa gttagtggta attcttcatt tcgttttatt
     9241 ttttctgcga ttttttcatt caaaagtaag ttagcttgat tccaagcttg gcgtgaattg
     9301 ctagataaag taacggacac ttttctcttt ttttcagtta agggatccgt ataacgttcg
     9361 gtgtacttaa attttttgtc atttattttt tctaaccaca ttatttctat tcctttcgaa
     9421 tatacgttcc tattaattgt taaaagaaaa agcccgaagg ctttttatat atttaatctt
     9481 ttgacaattc taaagatcgt ctatattgtt cagctttagc taattttgta aatgttactg
     9541 ttccattata attttctaaa acaactttct ctatttcgtc tagtgaaact ttgaaaaatt
     9601 cttttctttg attaatttta ttaacttctt gttttctaaa atgattatgc aatttagttt
     9661 ccaaagacgg agcgtcctct gaaaaaatca tcgcatgaac gtcaaattca aatggaaccg
     9721 atgcactact caattctttt attctatcca taggttctaa tcttctagtc ataccaattt
     9781 tatatatgtc ttcaccaaaa gacccaatat tactaattac atacacataa ccggctctag
     9841 tatttaattc tctttgtaat acattttcac gtataacttc taattctttt aatttttctt
     9901 ccagttcttg aattttattt gcatataatt ctttttccac atctgcatta gctttttgca
     9961 tatatgcgat taatttggaa atttcagaat tgaattgacg ttgttcttta tcaatacgtt
    10021 tcttttcacg atcaatttct ctacgaactt tttcctcttc tatcatctgt tcttttattg
    10081 ctttttgttg ttctttttct tcggtaattt tcactaaata agagtaatga agttctagtt
    10141 cttgaagttt aaactctaaa agacccttcc ttaattcagc attgtcattc ttgaataaat
    10201 tattaatttt atcaaatatt tttatgattt tttccctagt cgagtctata ttagaaatag
    10261 ttagtttatt gagtaatcct ttcacttctg aatcaaatgg aatgagcatt tttttcttta
    10321 aattattttt ctctcgttta tttaaaataa gagggacaga aacagcatcg tcaataatat
    10381 attccttttc ttttaatttt aacaaagaaa gcttattttt tatttcagaa gatgaagttt
    10441 cttctatatt tgaaacgata agtgaagaat agacattttt taatgtttca tcatactttt
    10501 gatttatttc atcatttaaa tcttctttct ctttttttaa taaaataata tcatttttta
    10561 acatagtaat ttgtttattt aaatctgata gtgtttcttc cttacttaat ataaatcttt
    10621 ctctatcatg taatttattt agtttttcat catttttttg ttctaattca taagcttctt
    10681 tttttattgt gttagctttc gacagtttag tgtttcctat aattaataaa ataagtccaa
    10741 tcaataataa cattcaaaac tcctcatttc tttgatataa ttattgtaga gtttactcag
    10801 aaatgaggaa agagtccatg tgaaagcatg ggctttttta tttttaatgt tgtaatacta
    10861 aatgttcaag attatgagga agccctaaat attcaataat ttggaactga ctcatatcag
    10921 ataaatcttg ttcatctatt gttctagtta acatttcaat tgcaaacata ttagcttcag
    10981 cttctatacc ataaatcata caactaaggt tgtttgctct aaaagctgct gtgcaaatac
    11041 ctttatggag tctaacgtgg gctatttcat gccataatac aaatcttttc atagaaggtg
    11101 ataggttttg attaattaat atcacataac atcttttatt gtgtatcgtt tgtcctaatg
    11161 ttttattccc taaatcagtt tcaattaaat ctatatcaga atatttgatt attttatatg
    11221 gattaatcgc atcagatcca aactctacaa ataatttttc tatttcttct aatatccagt
    11281 atttgtttaa atgcatacca aagcccacct attgacgata ttttttagga gtgaattttt
    11341 tctttgcttt aactttggtt aaggcaagtg caagttgaat ggcatcgtat aatttttcct
    11401 tatcttcatc gtctaaaggt tcaccataat aatttgtttc agcatctgaa ttcaagcctt
    11461 caagtaattt ttcagcttgt aaagcaatat cttgtttatc tttttctgtt aaatcataat
    11521 aatggcgttt atcagtacgt cctaaaagat aatcagttga tacattaaag taatctgcaa
    11581 ctttttgtat tttatctcca gatggagtac ttttattcca tctagacatg cttccatttc
    11641 cgaaatttaa ctttctttca agttctgcca acgtcattga acgttctttt aataagattt
    11701 ttatacggtc taatagcata ggatatgcat tcctttcaaa ataccgacaa aaaaagtatt
    11761 tttctgcaaa ttatctattt acaaatagag aatttgcagt tatactagtt ttgtaagcaa
    11821 gatatttacg gcatacaaag actaaaagca ataaactaat agtctcccca gacatcagta
    11881 agctcgcttt ttgtgcgctg tattttgtat gcttacataa tagcatattt gcagtttttg
    11941 tcaaacttat tagacaaaaa tattagaaaa tattcgataa gggggtatga agcatgactt
    12001 taaaacagca agtattaatt gctttagtaa agaaaggttg gagtcaaaga gagttagctc
    12061 gacgaatggg tatatcaatt acttatttac gagatatctt catcgaaaaa agaaaaccta
    12121 aggaacgttt aaaacaaatc gaagaacttt tggatatcaa gttagaagta gattctaatg
    12181 atcagccatc agaacaggag gcgtaaaaat ggtacaacgt ttgagcaaag cggagtttaa
    12241 agagaaatat aagtattctg aaagtactta tcaaagaaga atgaaggaat ttaaaaaatc
    12301 acgttttagt gaggggtata acgcagttac ttccaaagaa ataacaattg atgtcgattt
    12361 atatgaacag tttagaacat ggcgttctaa aaatcgattt agagttagag ctgtttgtta
    12421 atagctaaaa aatctaaatt caccacttct gaaaagagga gttgctgctc tcctttcaag
    12481 tttgccaaag tccacgtttt ttcattttgg caactcctct tcttggaggt ggtgacggcg
    12541 agagacgaag gagggatgac atgaaggaag aatcaaaaat agggattttg aatgagaaca
    12601 attacacaag attaattatt gaaacagaag aagggaaaaa agtagcagaa gttacattga
    12661 ccgatgcaac tcctgctgac ggttatcgta ttcgattaac tcctaaatat gattaacctt
    12721 ttggtgggtg tggatcgttt ccgtgactat cacggctttg aatttttcca tctctgccat
    12781 gaataaatag ctcagatcct tgatttttag aaatctctct agcgattttt actgcttctg
    12841 attttgtatt agtatgtgca gtcgctttag aatttccagc acctttgaca ttccaaccac
    12901 cattggaatt aggtacaaca tgttgatttt ttcccatagt tttcacctcc atttctatag
    12961 aaatatttta tcaaatagaa atggagaaat tcaataaacg aaaggagaag tgatatggca
    13021 tataccttgc aacaagaaca tcaaattctc ggtttgatta aacaacgcag gaaacaatta
    13081 caagatgacc gtgcagcgct tagaaaagcc gatgagctat cagataggca agctgaacta
    13141 attgcttctg aacttgagga tttgagaatg ctagaaataa aaaataggga gattagatta
    13201 tgaagaagac agacacactt tttataggat tcattttggg gttattagtg attgtagcgc
    13261 accaaagtat tatcggggga agcttgttcg cagcattgat ggttttaatc aatctgcttg
    13321 attcaaaaga aaggagcaac tatggcacga gaagaagcgc taaaaatcgg taaagtgatt
    13381 gctgataatc ggtggggaaa tagccgccct attattttaa gcaagcaaca tatcgaaaag
    13441 caaaaagcat ggcaacaaat aaaaaagtga ctctgccagc cagcaaagag tcacatacaa
    13501 atttataaaa ctaggagaat tatatcacat gaataagaaa attgaaaatc ttatcgaaga
    13561 attgaaacgt gaatgccaaa agcaaggtgt ttctattatt tgtacagccc aaaaagaagg
    13621 ggaacttaaa agtctcgttt atggtgagac aacagaaatt ttactttgtc ttgctatgca
    13681 agaagaacat ttagatgaaa atctcccatt gtcagcacat attatgcgta gaattgctgt
    13741 ggatgcttac gaacaagcga aaaatgaaga agaaaatcaa ccttcaaatc atacttttgt
    13801 tattaataac aaggaagatt tagctgatgt gatgactcgt attctcaagg gggaatttca
    13861 atgatgaatg aaaaaacaat tgatctactc attattttat ttttcacgtt agtgattgta
    13921 gcgaaaagtt atgtaatctt tggcttgtta ttcgcaatta ccatgcttgt gctttgcgtg
    13981 ttagcaagca gaaaagaggt taaacatgaa cgagttagca aatcttgaca actatttaac
    14041 tgatcctgat tatgctaaac caccatatga agcaccaatt gatgaggagg atgaagatga
    14101 gtaaatctac cttagaaatg agccatcaag aatggcttga agaccgtaag aaaggcatcg
    14161 gaggttcgga tgttggaaca attttaggat tgaataaatg gaaatctcct tatcaactat
    14221 ggctagaaaa aacaggacaa gtagtacttg aagaatcagg aagtgagccc gcttattggg
    14281 gtaatgtttt agaagaagtg gttgctaaag agtttcagga acgtacaggc aaaaaagtac
    14341 gcagaagaaa ccaagtattt gaacatccat tacatccatt tttaagagca aatattgatc
    14401 gggaagtagt gggagaaaat gccattctgg aatgcaaaac agccaatcaa tttctcggta
    14461 aagaatggga aggcgaagag gtaccgctta gctatctctg tcaagttcaa cattacatga
    14521 acgttctaaa caaagactat tgttacatcg ctgtcttaat cggtggtcaa aaatttatct
    14581 ggaagcggat tgaacgagat caagagctga tcgatacaat cactgaacaa ttagtagagt
    14641 tttgggaaac aaacgttctt ggaggtatcg agccaattat tgatggtagt caagcgacag
    14701 ctgatttctt gaaagagaag tatgcagatg ttgaagacgt tcaaacgacg ttaccaattc
    14761 atttcgatga actagttgaa cagaaaaacg aactcaaacg gactaagaaa gaaattgaat
    14821 cagctatccg tcaagtagac aacgagatta tcagcgagct aggtaaacgt gaagccagta
    14881 tcggtatcac tcaaaaaaac atcatcagtt ggaaatttgt ccgtacgaga cgtatgaact
    14941 cgaagaaact agcagagaaa tatccagatg tcgcaaatga tgaagagatt tataacgtta
    15001 ctgaatcaag aaggctaacc gaaagggaga tcaaataata tggcaacaaa tgaatcgtta
    15061 aaaaatcaat tggcagcaaa gccacagaaa caagttgcac caggtcaatt aggacttaaa
    15121 gctttgatga atacaccaac aatgagaaag aagttcgaag aggtgcttca tgacaatgct
    15181 aatgctttta tgtcgaatgt tatgactctt gtatctaatg acagttatct tgcagatagt
    15241 gaaccgatgt ctatcatgag tggtgcgtta actgctgcaa cattaaatct tgggctagat
    15301 aagaatttag gttatgcata tttagttcca ttcaatagta aaaacaagca aacaggaaaa
    15361 tgggaaaaga aagctcaatt catgcttggc tataaaggat atatccaatt agcccaacga
    15421 tcaggtaaat acaaagcatt aaatgtgatc gaagtttacg aaggagaact aaaaagctgg
    15481 aaccgactga cagaagagtt tgagtttgat ccaaatggta gaacgtctga tgaagtcatt
    15541 ggatatgttg gctatttcga gttactgaat ggattcaaaa aaactgtcta ttggaccaaa
    15601 caagaaatcg aagctcatcg gattgctaac aataaagatc gcgataagac aaagttaagt
    15661 ggtgtgtggg catctgatta caatgcaatg gcacgaaaaa ctgttttgag aaatcttctt
    15721 tctaaatggg gaatcttgtc catcgaaatg caagaagcca ccacatcgga tgagagagtc
    15781 caaagggttc aagaagacgg cagcattatt gctgaaacag aagttgaaga agatattcct
    15841 gaaagaaaag aagcagaggt tatatctgaa gaaaatgaag atgtacaaac tggattattt
    15901 gatgcatcta atccgccgtt aaacaaataa tgagggagct ttctcccttg cttttctaga
    15961 ggagaaatac gaatgaacac aggatatgtc aaattacatc gaaaagtgat gaattcattc
    16021 gtttggacca atccttatat gtataaatta tggaacttgt gtttgatgaa agcgagtcat
    16081 gagaatcgca agatactttt taatggaaaa gagatacaag tgaacagcgg agaattcgtc
    16141 acagggcgcg atgctatcac atctgagatg aacgaaggcg tgaaacgtga acatcaagtg
    16201 aacagcggtt ctgtatggag atggctaaaa caatttgaaa aaaacggaat gttgaacatc
    16261 aaatcaacta cgaaatacag cgttatatca ataaaaaact ggtctttgta ccaaagcagt
    16321 gaacaacaaa tgaacatcaa acgcacaaca agtgaacaac aagtgcacac aaacaagaat
    16381 gaaaagaatt ataagaatga aaagaataat aaaacatcat cgtcgcaacc acgcaaaaag
    16441 cgtgtttacg acaccgactc agtttactac attctcgcgg aggagttatt caaacagatt
    16501 tgtcagaatc aggaaatcaa aaagccgaat ctgcaaagtt gggcagatga cattcggaaa
    16561 atgatcgaga tcgacaagcg gaccgaaaac caggtacggg gaatgattga atggagtcag
    16621 cacaatgtgt tttgggcatc gaatatttta tctgctaaaa aattgcgaga aaaatacgac
    16681 acaatggcag cgcaagcaaa tcgtgattat aaaacaaaac aaactaaaac gcttgaatac
    16741 gagaaattta gcacagatga gttgcctatt tgagaggagg cgtaggcatg gaaactgttg
    16801 gggaaatcat ggaaaagctg atacagaaag tgcttgtcca acgtggcgaa tgtcctgaat
    16861 gcggacagcc tttgtatgga tggcgtacga agaaccctga tggctcagaa cgttgtaagc
    16921 caacctgtat gcaatgtggg tataaagcat tgcgagttca ggaagactta caaacagaac
    16981 gaatttacaa cgagagcctg aaagcaagag caatcaattt tttcaaaggt ggttctgttg
    17041 tgcctaatca agcgttgttt gattgcacat tgcagaatta tcaaattgtc gatcaagaaa
    17101 caagacaagc ggttgaagta accaaacgct ttgttaattc agtcttgtta ggaaatccaa
    17161 gtcaccttgt tttaactgga aaacaaggaa caggtaaaag tcacctagcg atggcagcgg
    17221 cttgggaagt cttgaagcga tcaaactacg ataaaaaaat cttatttatc gggttacagg
    17281 aaatgctgga tcaaatcaaa ttttcgtaca acaatcctga actcagaaaa acgattgagg
    17341 gatcgttgat tgcagatatc aaaacagcgg atttagtcat cattgatgat atcggttcag
    17401 aactaggaaa agatgcatca gatagtcgag cgtttggcat aaacacgcta aattcgttct
    17461 tggatgcacg acagaaccta gcaacgatta tcacaacgaa cttgcttggt gaagaactga
    17521 aaaaagctta cggtacgaga acaatatcaa gaatgtttgt caactctgat ggatttacga
    17581 tggtattttc tcaaacagca gacaagcgca taaaaccagt caaaggagcg atcgcatgaa
    17641 tttgactaaa caagaaaaaa gaatctgtcg tcagataatg ttgcaaatta taggtgatcg
    17701 tgacatggac gaattatctc aacaagagag tcgaatggtt cggaagataa gtaagctaat
    17761 tatttatcgg gatacagaaa gatttctcac tgttttaggt aacgtctacg agaatccaga
    17821 gttattggag gtagagtaat tgccaaaaat attagatgca tgttgcggta gtagattgtt
    17881 ctggtttgat aagaacaatt ctgacgtaac atttatggat tgtcgtcagc agtatgaaga
    17941 attatcaaca ggtcatgtga tcaatgttga tccagatgtg gtcgcagact ttcgcgatat
    18001 gccttttgaa gatgatgtgt tcgatatggt tgtatttgac ccgccacact taagacatgt
    18061 cggcgaaaac tcatggcttg ccaaaaaata tggaaaatta gacgaacttt ggccagaaga
    18121 catcaggcaa ggttttgcag agtgtatgcg agttttacga ccttcaggaa cattaatttt
    18181 taagtggaac gaggaacaga taccactttc tgatgtgtta gaggctattg gagaacagcc
    18241 attgtttggt aataaacgaa gcaaaacaca ttggcttgtg tttatgaaaa aattcagcta
    18301 acggaggaaa caaaggagga aaagtaatga agattgtatt aaataaatgt tttggtggct
    18361 ttgggttgag ccatgaagca aaaatggaaa tttttaaaag aaaaaatatt gaagtattcc
    18421 catacatcaa taactttagc tatgactcag atgatgaata cacgagatac acaggccaaa
    18481 agctaggttc gatggatttt atctactatt tcaaaaaaga cccgaaaatc gacaaagtta
    18541 caggaattta tagcgaaatt gaccgactgt acggaattgc tgatgattcc agtttttcaa
    18601 gtgattcaaa cagaggtgat aaggacctcg ttgctgttgt cgaaaaacta ggaagtgagg
    18661 ccagtggacc atatgcaagt cttaaagtcg ttgatatacc cgatggggct gagtgggaaa
    18721 taagtgatta tgacggcgtt gaaactgcac attatggttt tcaaacaggt agtatttagt
    18781 ccactaatga caactaaaga ggaggcagaa ggatgagtga agatgaatac tttgaacagt
    18841 agtctattaa cgacagagat ttttaactgg aaaggggtgt agtcatggac gcatcggaag
    18901 tagtaaataa aattaatagt ctcaaagagg ttttcggaga cgtcgaagta gtgataaacg
    18961 cacaaggcta tgacaacgaa ttttttaagc agattaccga cattagcatt cagcaaggaa
    19021 tggaagacga agacggaaac tttatcgatg aagtagccat tttagtgact tgcgagtaag
    19081 taattgacag ctaaagagga ggaagcggaa tgaaactaaa agacggattt tactccagcg
    19141 gccacggcat cggcggttta atgctagata tgccgacaaa gaatcctaaa acacgtaaga
    19201 aaccaaaatt caaagtcggt gacatggttc gctgcgaagc agaaggattc atctatccat
    19261 ttcgtggata tgtagaacac gtctataatc actcagcaat cattcgcatt gaaaacacga
    19321 tggaatgtga taagtggtta gcgaaaagca aagagaattt agcagtggtg agattggtgg
    19381 acatggaagt tataaaatct taattttgct tttttacaac tatcctacaa caatgagcgt
    19441 tattccacaa ctggaaggag aagaggcaat tgtgaacatt ttagagaata tagatattaa
    19501 gcaaacaagg aaaaatgcta gacgattact aaaaagatac agaaatttag aacgtttggt
    19561 cggaccagtg aaaatagact tttccgtgat gactgttacc aaaaatttga aattcacaat
    19621 tgacagtcaa aacgaagaaa tcattgaagc gataagtact cgagattcgg ttatcgaagc
    19681 attaacacgg ctaagtagaa tccatttcca ggtactttat tatagttatt gttttcctaa
    19741 taagatgtca atgtatcaaa taggagaaaa attaggatat tccgatagaa ctatcgagag
    19801 aatgaaggca gtagctttgg ttgaatttgc tgaggcgtat aaatcaggag aactcatttc
    19861 acgtacaaaa taaaaaaagt cggattcctc cgactatgaa taatatttcc gacataagta
    19921 ttatatcata attgggggaa tcagaggatg gtacttttcg atgtaaagaa atatgagaca
    19981 ccaagcgcga aagatgttga tatggaacgc acaaaacata atgtcgctgt gtttctttca
    20041 gcatatctat cagctagatg tagagtaggg caacatcgag aaccaaaagt gacagcatct
    20101 tattccttgg ttccaccttc tacagctgat catatatttg aagcagaaag aatgctgatc
    20161 gataaagaag aagcacagga agaatttgag tatctgcata aattgtttgt tcgaggctat
    20221 tcagcgatac agcatccgca taagcctgat gtgactgaaa ggcgcaagaa gatattctat
    20281 gatcgttata tcaatggtct gcccatttat gtaactgctc aaaggaataa tactagcgaa
    20341 gaatcggtta aagtagaatc aaacagaatt atcatccaat ttgcttcatc gttagaactg
    20401 gttgctttca agtagccagt ttttacactt tttataccct tttattacca atttggtttc
    20461 cattttatac cttttttata ccaatcactt acctattcaa cgttgtatta tgatagtgtc
    20521 gaaaaattag gaaacaggat cgacaaaata aaatgtaagg gaggaaatct ccctcatcgt
    20581 ttaattaagc ttcgataggc agcaacggaa atattaagaa taaggatgtg aatttcaact
    20641 ccttctaaat tgttcttatt atctatcatc cgttgctgtc tattgttttt ttaattattc
    20701 acacgataac taaaggtaag tgaagagaaa tgattccatt aataatttca atttttgcgc
    20761 tttgtcttaa tgtatatatg attggattta aaaatgggca aaataaaaaa tagtagcagc
    20821 caagaataat tttatagtgt cactgtggcg gaaagggtag acgctaagca tgtgtgctag
    20881 gtcaatgctt cggcaaccat gcaaggttcg attccttgcc agtgactttg gcaaccgagg
    20941 catcggcggt ttaaaaatat aggggtgcgc aatttcgtac gcgttttgtg catcgtgtag
    21001 gttgctatta cataactggt taggttagat tgagatttgg gattcggtac aaatgaatcg
    21061 tcaaatgtct caagcacagg atcggaaacg tccctgcctg tgcattacat attagatcac
    21121 tctttgagtg gtctttttct ttacataaag gaggctacat aatgagaaac tactggtatg
    21181 tatcgctaac taatgaatat cctcgaacca ttgatgattg ttcagtgcgt gttgtgcgtt
    21241 ctgtacaaat caaagggaag tactctattg tcgaaatggg gagagaagca gaaccatgtg
    21301 agattgatgc gtgcaagctc gtttattgcg gtcatggttt ctatgatgaa ccaaacattc
    21361 aaaataatat taacaagaat ttgagggatt agaatgcaag aaatggctta aaaatctcca
    21421 atcaggacaa atcaagttag acaaagtttc cgatttaaag atattgattg aagctgattt
    21481 aatgctaaaa gatattgaaa attagaaaac aaaactcaac ctaaacagaa tgtgaggtgg
    21541 tgtgtattga atggcaagac aacgtgatcc aagacgtgat gaagccaaaa gaatttggtt
    21601 agaatccaac ggagaaaagc agttaaagga aattgcatct gaattaaatg tttcagattc
    21661 tcaggttaga aaatggaaat cgcaagacaa atggagcgct gaattgatta gtaacgttac
    21721 caatggcaaa agtaacgtta ctaatcaagg tggcgctcct attggtaatc aaaatgctaa
    21781 aggtaacaaa ggaaatagcc gagcttctcc gccagtgggt aataaaaacg ctttgaaaac
    21841 aggtgagtat gaaacaatat tttttgacac gttaaccgat aatgagaagg acatctattc
    21901 tagtttgaat gatgatcctt cttttgcttt gtccgaagaa atacgacttc ttaaaataag
    21961 acaacttcga atgatgaaaa gaatccaaca agctgaagct ggactaaatg atgaagaagt
    22021 cgaacgattg cagcagctaa gaaagattaa aactccgatt gaaaaaaatg gtaaaaagct
    22081 agaaatcaag cgtgaggtta tgcaagatgt gcagattagc agaaaaaaac atcgcaaaat
    22141 tgatgatatt ctttcaattg aagattcatt gactcggatt agcaaccagt tagctaaagc
    22201 catcaagcaa atgaatgaac tttatatgaa tgaatacaga actgatttaa ttaaagctca
    22261 gactgataag atccaagctg agacaaatga aattggcgga aataattcag gtgaagaaat
    22321 agaagaatgg aaacaggcag ttttaaatgc cgcaaacaaa cgggcggtga aagaaaatga
    22381 ataatgaatt tattcctttt gctgatattg gttctgccat tgattattac tatgataaac
    22441 cagtagcttt ttgccaagat attttgcatt tgaatcctga tgaatggcaa gaaaatgttt
    22501 taaatgattt agctgaattt tcaaaggttt ctgttcgttc tggtcaagga gttggaaaaa
    22561 cagcattaga agcaggagca atactttggt tcttaacgtg tcgaccctac gctaaagtaa
    22621 tagcaacagc tccgacaatg aagcaacttt acgatgtact ttgggcagag gtagctaaat
    22681 ggttaaatga tagcttgatc aaaaacttac tgaagtggac aaagaccaaa atttatatgg
    22741 ttggtgattc agagcgttgg tttgctacgg ctagaacagc gactaaacca gaaagtatgc
    22801 aaggttttca cgaggaccat atgttgattg tggtagatga agcttctggt gtgtctgatc
    22861 caattatgga agctattctt ggtacgctat caggttttga taataagctg ttgatgtgtg
    22921 gaaaccccaa taatattgaa ggtgtctttt atgattccca taattcagac cgtgataaat
    22981 acagagttca taaagtatca agctatgata gtaaacgtac aaacaaagac aatatagaaa
    23041 tgattcttaa aaaatatgga aaagaaagtg atgttgctcg tgtccgtatt tttggagaat
    23101 ttccgaaagg tgcgttggat tcatttatca gtcttgaaac agttgaattg gctacagaaa
    23161 aacaaattag tgattcttta gtcaataaaa caaaggttgc tcatattggt gtcgacgtag
    23221 ctcgatatgg tgatgattct acgattctct ttcctagaat tgctaccagg gcattggagt
    23281 atgagaagta ttcaaaacgt agcaccatgg aaacaacagg atatgtcatc aacatggcca
    23341 agaatctaat gagtcaatat ccgagtattg ataaagtgat gattaaagtc gatgacactg
    23401 gtgtcggagg tggtgtaacc gaccgcctag aagaacttat agaagacaaa cattatcctt
    23461 ttgaggtgtt tggagtgaat aacggttcaa catcagaaga cgatttttac gataatttag
    23521 gtactcaact atggggaaac atcaaggaaa tgttagaaga aaatatgaca gcaaatctta
    23581 acggagaaca gcctgttatt gaattgcctt ctgatagttc gttaatcaaa gaattaagta
    23641 ctcgcaaatt caaaatgaca agtagaagtc gtatacgttt agaaagtaaa gatgatatga
    23701 aaaagcgaaa tattggtagt cccgatattg ctgacgcact ggctttagcg ttttatgagc
    23761 caccaagtca ctatcaattt attcaatttt aggaggtgag cttttgatta gtacagtatt
    23821 atctttagag agatataaga agctacgtgt taaatatgca acacaaattg aagatggaat
    23881 gtttgatccg aatggtttta tagaagatat gaaaccattt tttgctgatc gcgaaagaaa
    23941 atatctagct tatactagcg aaaagaatga aatagataat agaccaaagc ctaacactga
    24001 tattgtaaaa gttaataata aacttcatgc tggtatgtat tcaattgtcg tagaccaagc
    24061 agtcaatcat tttactggta tacctatcaa atgggattac gatgtatcgg aacaaaaaag
    24121 aacactcatt caaagattaa aagataaatt cttaaaaaat gatatagaac ttccgacagt
    24181 tccagaagct tttaacaaat taacaagcaa tcttgattcc atgagattcg caatgcttga
    24241 ttctgaaact gcaacttttc aaggagcttg tggagtagct ttccgattgc tagagcctgt
    24301 ggaagaagat gatggttgga agttaagagc aagtaatatt gaaccttgga gagcagaaag
    24361 atatggaaat gccggaatct atatcaaaga aaagtatgac tcttaccaga aaaaattttt
    24421 tcaagaaatg aaagttatga caagaaataa aattctgaca tatgcttgct atggtgattt
    24481 gaattttgtt acaagcggaa cgttcaaaaa aattgatgag accgataacc ctttggggac
    24541 gattaccttg gcagaattta aaaataatac gaatcgttat tgtgattttg aagtagctga
    24601 ggaaattgga gatgcaattg atcgtgcttt gtctgatcaa caaaacgaaa tcgaacaatt
    24661 taagcttgcg tacatgcttg ttactggcac aacaatgagc aaaggcactg ctaaagaaat
    24721 gatgaatcag ctagggatta tcaacttaaa agcccctact gcaaaagctg aatatgtcac
    24781 aaaaaattta gcaaaagatt tcaatgaata tcatatggat ctattgaaaa aacagtttta
    24841 caccatttgt aaagcaatcg attttaacga tgaggtgttt aaatcaaaca gttctggaga
    24901 agctcgcaag tggcaaatca ttagcctaga agcgaaaaca aatactaaag agcaatattt
    24961 tagagaagga ttgaaagaat gcgcagaaac aattgctgct tttcttaagt ttcatgacaa
    25021 agtagaaatt gagcctgaaa aaattatttt tactttctct agatctttgc caactgattt
    25081 aagttattta gctgaagctt tacctaaact tgcaccatac gtatccaaac gaactattca
    25141 gagccaaatt ccatttgtaa cagatgttga ttatgaaaat gaaatgatgg aattggaaag
    25201 tggaagtgct tatccagata gtgaatacaa ttttggcgga ggtggcaata gtgacgatag
    25261 aaacgaagta ttggaccaaa cgtcgagaac tggaggatca agcaaggctc aaacaagaaa
    25321 atcagacact taaaaaatta actagtgtat ttcctgaagc actgaaagag atacaagcaa
    25381 aactattatc acaagctgac ttacacaata tcacttatcc agaaatgatg gagttttaca
    25441 gtacaagtaa tcagaaaaaa tatcgtgaat atgtggaaaa aaattataag tcattaaaaa
    25501 tgtatgatgc aaaatacaaa gagtttatcg atgaattttt tccaccattt gactatgcaa
    25561 aagtcaatcg cttattacaa atacgatcag atgtatttaa aattcttgca gaatatgcga
    25621 tggatgcaga tgtgaatcaa tatttttctg atcgcttaga ggaaattctt caaagaacat
    25681 attcttctaa tgctaatgtt tttgttcaac ttttaaacgt tgatatacca aattatttac
    25741 cagaaaatga aattaaacat tatttgaact atccatggtc aggaaagaca ttttcaagaa
    25801 gactttgggg aaatatttca tcgcttgaac agaaactctc taatgctatt gtaaaaagtg
    25861 ttgctagtgg agaaggcgtt atacacgcat taaacaccat gagattagac tcagaaattt
    25921 gtgacatgtt taagttagaa gaatcaaagt ataacaaagc gatagaaaat ctcgttcgaa
    25981 cggagtatgc aaaatttgca caagatggta ttgaaaaatc atatttagaa acaggtattg
    26041 aggaatacaa cgtattgact gcaaaagatg agagagtttg ccggatttgt ggaggaaagg
    26101 caagtaagaa tccctataaa ctgaaagatg ctgtcatagg tgaaaatcga gcacctttcc
    26161 atagtcgttg tagatgtacg gatgttccta atttaccaaa attaggaaag gatattgatg
    26221 aagaatatga ccgtttattt ggcgatttat tagatgagtt tgcacatgat tcttttggaa
    26281 ttaatttgaa acggaggaag tagaatgaaa gatttttttg aagcagtact aacaattaat
    26341 gtaaatgctg atattgcaga agcctacaaa acagctattg agtctgagaa ccatcctaat
    26401 ggcttgagag accattggaa tggcaattat gcctacgtgg ttattggcga tcaaactgtt
    26461 aattatcaag ataatactcc agttgataag aataccgtta atttaacgat tcaattatta
    26521 tctcattcat taccaaattt aaaagaaaca gttgattggt atgaaaagat gggatgtatt
    26581 gttgttagaa ctgactacaa agaaggaaag tctagtaatt aggctttttt attttgtccg
    26641 aaatgacgtt aaactagcgc aatactgggc ttggttgaat ggtggggcgc aactattaaa
    26701 actcaaagca atgcggggcg tgaaaacgaa tcgtggggcg aaaggagaat gagcatgaaa
    26761 cacaaatcat taatgccaat gaatttgcaa tactttgccg aaggtgacga tcaaaagttt
    26821 tcttttgatg acttcaaatc ttttgtggaa tccaatgaag aagctcaaaa atttattcag
    26881 tcacaatctc aaagtgttgc cgacaaacaa ttggaagctt ggaaacaaaa taacttagat
    26941 aaaattaaac aggataccat caaggaatat gaggaatcta agaaaaacaa gtcacctgag
    27001 caaattcaac tggaaaaact acaagctgaa tttgaagcag aaaaagcgtt gcgtgtgaca
    27061 agtgataata aagcatttgt tgcagaacaa attgctggat tagaactaga tggagagtta
    27121 aaagagtcta tttctcaatt tatgctaaat aatcttgtta gttcggatac agatttcact
    27181 aagaatgctg ttgaaggttt tacaagtgtt ttgaatgcaa ttaatgagaa acatgcagat
    27241 gcattaaaag aactacaaat gaagtctgca tttggtggaa ctcaacaatc gaataaccag
    27301 gttcagcaga acaatgaaac attaacaaat ccagaagaac aattaggaca aattcttcaa
    27361 caatttaact aggagagtga aaaattatga aaaaaacatc tttaaataat ttagagtatt
    27421 tggatatttc accagcgatt aatgctatgc aagtaccaaa tacacctttt ttaagctatt
    27481 tacttggtgc tggaaaaaca gagccagcaa actcgacaga aattaaatgg cgtgaatatg
    27541 atatcaacaa cgatgattct tctgaaaaac ttgagggcgg agaatatcca gatgctgaat
    27601 caggtcgaac ttggtttaac aactatactg aaatttttag aaaatcaacc tctgtatctg
    27661 gtacattaga tgctattaat gtgaatggag tcggaaatga attaactaat caagtagcac
    27721 tacgtggtat ggaaatgaaa attgatttga accgaaaatt gattactggt gtaaaagctg
    27781 atgaaaatgg ttctaaaggt cgtcgaatga atgggatttt gaacttgatc aattcagcaa
    27841 ataaggcaga aacagccact gcgggtgcag taacaagaaa agatatcgat actttattta
    27901 aattgatgta tgaaaaaggt tatatgggag aaaaactatg cttgatttct ccagatatgc
    27961 aggagttaat gactgatgag ttagatggaa aatcaacaaa aattgttcag ttcggggaaa
    28021 gagtaacttt tggattgcaa attggaaata tcgtgtctaa ttacggtaca ggtattgctc
    28081 tactagaacc atcattgcca aaaggaacaa ttgccgcaat cgatactaat tatgtgaaac
    28141 tacgtccatt acgtgaatgg agagcagaag aacttgcaaa aacaacggat tctagacgta
    28201 tcggtcttgt aggtgaatac tctcttgaat acaatgcttc aaactctggg gcaattttaa
    28261 atttaaagtc tgaataaaag ggagttagta ctcccttttt tgataggagg aattacagtg
    28321 gtaaaaaaag atgaaactaa aaaagatgaa gtcgtgaaat atagagtagg taaaactaaa
    28381 aattttgttg ggtttgttca tcctaaaact cgtagattta tcacagcaga ttcaaataac
    28441 gaatttatca tttctataga tgataaagaa gcaattgcaa ttttggaaga tgcaattgat
    28501 gttaatgaaa tttaggaagt gatctgatgg atgaatcgct aaaaacggaa atcattgagt
    28561 ctacaaaaga agattttcca gatttgagtg aagaacgcat aactaattta ttagaaataa
    28621 ttttgctaga aattgaatca tacaacactt gtaaaaatga tatttcatgg gaaaagttaa
    28681 aaagcgtgat tagtgaagtg ttgtataaaa taataaaaaa tgaatcagaa aaaacagtat
    28741 cttcagttag acgtggcgat acaacgatta gttatgcttc aacaacaaat gatgttagtg
    28801 agttacttct aggctatggt gatttgatac gaagagttat tggttgtgga ggattggagt
    28861 ttttttaatg aatgaagcag atattttaga aactacttat gaagatagtt gtattattga
    28921 aagactgacg gacattgaag attctaatac aaatattact attcaagatt acaaaaaagt
    28981 atatgataat cctatttctt gcgctctttc acaaggtcaa atcgatggac tagcagtcat
    29041 agaagatgga gagatggtaa atgtttcaac tgacacatat aaattatttg ttcatcctaa
    29101 gattaaacta aaaaaaggag atcgaataac aataactcaa aaggccagtg gcttaatttt
    29161 ttctctattt gctactaagc ctttttacta tcctagtcat tgtgaagtga atttgatagg
    29221 aagtgagaaa aatgggtaat ctcaaatatg aatcaaatgc agaaaagatc attgagaatt
    29281 ttaaaaatat gactgtaatt gctcaaaaag aaggaatatc cttcgttaac gattcaatga
    29341 ataaagtcgt tagtttagct aaaccattaa ctcctgtaaa atcaggtaat ttaaggcgag
    29401 gatatcgtgt agtaaaagct agaaaactat caagcggtcg aattgttgga gaagttataa
    29461 acaatgaaca ttattttaaa tatgtagaag aaggtcatag gactaaaaat ggtggctttg
    29521 tcaaagggaa attcatgtta actcgtgcaa cgaatcttgc aaatatgtct tatattcctc
    29581 gaagatttaa acaaatggca ataaaaatcg ttaagaaagg aaagtaacat gaaagatgaa
    29641 atcattgctg caatcagtag caaattaaaa gaaatctatc ctgatgggac aatatatctt
    29701 gattcagtta tgcagtcaac taaagatttt tatttcgttt tatcagtaat ggaatctgga
    29761 actgaaaatg taggaattga tattcaaaat gtttctttct taattgatat tgcattgatt
    29821 gataataacc ctaatagaaa tttaattaat gaattagtct cacgttgtgg gacttttttt
    29881 aatacgatta caatcgatga gcaaatatta tttccaaaag cctatttacc tgatgaagca
    29941 gatggtgttc aacatattcg ttttacatta gaatttccac aatatattga atggagtgaa
    30001 agataaatgg gagaaaaaag aagtaaaacc ggaattattt ctgtcgaaaa acctacttgg
    30061 tttcctttgg aagatgagac agggaatttt ccggtatatg gtactgcgtt gccaatggga
    30121 acagcagtaa gtatcaaacc aacagctaat tatgaaacaa cacaagatta tggggattca
    30181 gtggttcaag atcaatttac agcttttggt ggtgcagaag ttgaactgga agcaaatgga
    30241 tatactcata aagttttatc tacaattact ggagggaaaa ttgttaaagg tggtgccttg
    30301 cgttctggag aagatattgc gcaagatggt gcgtttgcat atagacgtaa aaaatcgaat
    30361 gggaaatacc gttatacggt cttttataaa ggacagtttg ctctagattc agatgaaaca
    30421 tcaacgattg aaggaagtaa agtaagtttt actcatccaa cttggaaggg ttcatttgta
    30481 gatgtaccag gacttggata tatgtattca gttgatgaag atgatgaagg cgtggataaa
    30541 gcaatgatcg gaaattggtt tacaaaagta gcaattccaa ttgaagaagc agaactttca
    30601 ggaggtacag aataatgtca aaatatcaaa caacgattaa attaacgaaa aaagacgaag
    30661 aaggtaaata tgagcaagta caatttaaat ctgctgaatt tttaccagga acagttgtag
    30721 aagatgctgc aggagttatg gaagaaatgc aaacagcgac tgataagcaa tcagttaaaa
    30781 aagctttaag tcgtgcttat tcatttattg cagatacttt atttgaggga caatttactg
    30841 gtgaagatta ttgcaaagga attgatgctc gtgagattgc ctcattgaca ggaaaattat
    30901 tgaagtctgt tactgcaggt tttgatgaaa cttatacaga gacgaaaaaa aagtaagtga
    30961 ggcgctcaag tcaccttcat ttaagtattc gattacttac cgagaattag atataaagac
    31021 gcaattactc gaagcaggtt ggacgttacc agaaattgaa cgtactgact tggatgagtt
    31081 aatgcgtctt tttgctttta gagatgcggt aaaagagcat gaagatgttg agtactatga
    31141 taatttcact caattttagg aggtgatact ttgaataacg atgacctaat tctgaagatg
    31201 atactagatg aatctggttt tactgccggt atgaataatg ctgtcaaaaa gttgaactct
    31261 tttgatgaaa caatcgaaag aaaaagtaga aatagtggca gttcattagg tagtatttgg
    31321 aaaatatttg ctggaagttt tctagctagc ggagtaacta gaatcgtagg agctggcttt
    31381 gatctaatca agggttccat aagtggagcg gttgatcgag tagatacgat gaataacgct
    31441 ctacgaaatt tccaaaatat gggatttagt aattcagaaa ttatgaagaa tatcggaaag
    31501 aatgggcttt tatctcaagg tattcaagga cttcctactg ctttgaatga tgcgataagt
    31561 catgttcaac ttcttgcttc ttctacaggt gatttaactc gttcaactca aatatttaaa
    31621 gctttaaatg atggaattct tggtttcggt ggttcaactg atcaagttaa tgaagctgtt
    31681 attcaattat ctcaaagttt ctcaaacgga aaagtagacg cacaaacttg gaactcaatg
    31741 atcaacgctc aacttggacc tactctttct gctattgcta aaaagatggg aattacaatg
    31801 ggagatctga aagaaggttt atctcaaggt aagatttctg ttgaagaatt ccaaaatcaa
    31861 ttaatagaaa tggataccaa aggtggcgga ggacttaaat cattaagtca aatcgctaaa
    31921 gattctacta agggaattaa aacctctata caaaatgcaa aaacagctgt tacacgtggt
    31981 gttggtgagg taatagaagg attaaataaa gcattagtag attcagattt aggtggattt
    32041 aagggaatta ttgataaagt gggcagttca atggaatcgt tcttaaaagt aattgctgca
    32101 aatattccta cagcagtatc atttttaagt aatttattta acgaaattca aaaatttggt
    32161 tctgctttga aattcatgat gccctttctt gttcctgcag ctaccgcttt tggagcgttc
    32221 atgtttcaac ttaaaggtat accagcaata ataaaaagct tcaataattt taagaatgcc
    32281 ataattggcg ttggaaattc attaaagatt atgggggcaa tagctgctgc taatccattt
    32341 gttttaatta ttggtgcagt cgttggtgca atagctgttt tcggttactt tatggcaacc
    32401 aatgaagagc ttagaaacaa ggttatatct atttggaatg atgtgaaaga ttccgtaatt
    32461 ggtgtattaa aaaatataaa ggactgggga attgatactt ggaattctgc taaagaaatg
    32521 gcatcaaatg cagttgaggg tgtcaaagat gcttggtcag gaacaaagga atggttttct
    32581 aacacctgga aaggtattaa ggatggggcc acaggtttat ttgataaaac agtagagact
    32641 tcaagaaatg cagtcgatag tgtaaaaaat gcatggtcta atatgaagaa atggttttct
    32701 gatacttggc aaagtataaa agattcagcc agagaaaaat ggaatggaat caaaggttct
    32761 attatgtcag ttgctggtcc attgattaca ggtataaaga atgcattttt acatgttact
    32821 ttttatctag agaccttatg gaataattta gttgagattg gtaaaaacgt ctttgagatt
    32881 ttaaaaaatg ttatacttgc gccggttttg tttattacct ccatgatttc tggtggatgg
    32941 gaagaaacaa aaaataatat gattgctgtt tggaataata ttaaagaaag tgccataaat
    33001 atttgggaat ctataaagaa tatatttgta agttatttta caaatattta ttttgctgca
    33061 ctcaatattt ggacagggtt caagcttaca ttgataaata tttggaatga agtggtaaat
    33121 caagctaaat cgatttggtt aaacataaag tattttttta ttaatctttg gattgatata
    33181 aaatattttg caattcagaa atggattgaa ttgaagtttt ctattattca aacttggatc
    33241 gatttaaaat ataatgccat tactacttgg aataatatta aacagttttt caaagatact
    33301 tggaaaaata ttaaagatac ggcatacaat acgtggattt ctataaaaaa taccatgatt
    33361 aatacatgga ataacattaa ggactctttc tggaatattg ttactggaat tgttaattct
    33421 gctgaaaatg catggacaaa tctaaaaaat ggtgtttcaa atgctattaa tcgggtaaaa
    33481 gaaatcttta attcgttaag ggaagtcaat ttatttgaaa ttggcaagaa catcattgat
    33541 ggacttataa atggtgtaaa agaaaagtgg aatgctttga aagatactat caaaggtatt
    33601 gcaggtaata tcaaaaattg gattaaagga gctttagata ttcattctcc atcaagatgg
    33661 atgcgtgata tggttggtaa aaatattgtt caaggtatta tcgttggtat tgataaagag
    33721 caaagtaagt tagatcaaac catgacaaat ttagtaaaaa caccgtctgt tcaacctgta
    33781 gtaaatggaa taagtcacct accaattaca caaacaaagc aaaatatatc tgctagtgaa
    33841 acaaaagaaa ttcatttaca tttaaatgtt tatggagatt tacctgattc aatggttcgg
    33901 aagattacca caaaaattaa aacagaattg acaagacaaa tgaaacgaga tgctggtgca
    33961 gtaggaggaa cattatatgc aacttaagag aggacaattt tttattaatc aacattattc
    34021 ttctgaattt aatgtgtata ttcaaaacag gcctgcttct gtttcagcta gtcgagtaat
    34081 tgaattgaga gagcgagaag gaaatgattc tatcattatt gataaaggct attacaaaaa
    34141 tgtgactaga aagattgagt gttactataa agcaccttca attgatatgg tgcaggagtg
    34201 ggaagatcga atcactgaat ggttagatat gtcgtcttat agtgatttta ttctttacta
    34261 tgatgaacaa tatatttatc aagctgtagt aatagaagga cctgaattta aaggaacaag
    34321 aaaaacagga aatattgtcc cttttgaatt tacagtgagt attcgaccat ttaaggaaaa
    34381 ttacaatggt agatttacta ttcgacaaac agaaactttt gaaatttata acccagagaa
    34441 gtattcttca aaaccgctta ttaaattgag tggttctgga gatgcttctt tttatattaa
    34501 taaggataaa tatgatttga aatcgttgga cagagaatta tttatagatt ctaaattaga
    34561 agaggcttat cgaaaattag atggtaattt agaacatcag gatcaggtca ccttattttt
    34621 agattttcca tttttatatc ctggaaaaaa tgaaattaaa tggacgaaaa atattcattc
    34681 atttgaaata atgcctaggt ggtggagaaa agtatgaaac caagaatata tagtcctact
    34741 gaaacagatt tctcaacgaa tggcttagga attttaaagg attgtacaag atgtggaata
    34801 tatgaagtag ctaatggaaa atatgaatta gagttggatt atcctttagg aactagattt
    34861 gatgaatatt ttgaaaatga ctatcaaata aaagcaaagc caaacgatca agaagagtat
    34921 catatctttt ttattgatga taaagatata gatacttttt taaatacagt aactatttat
    34981 gctcagagtc gtacaaatcg acttggaaga cgggtagtca ctcttgtgga agtggactct
    35041 aaaactggtc aagaagcgat atcaattatt gaaactaaaa tggataaaaa atctgacata
    35101 cgactttatt ctgatattac ggctgtttct agcacaatct ttgaagcgag aaatgtttta
    35161 aattgtattg ctggtgaaca aggatcattg cttcaatatt ggggcggaga aattaaacgt
    35221 gaaccattta agctttcttt gttaaagcga agaggtcgca ataatgttgg aacgattcgg
    35281 tatggaaaag atatgtctgg tttgaaggtc aaattagatt ggacaggtat aaaaacaaga
    35341 attattccat atgctgatcc tcaaagtgaa gtaggtacga ctaatcgaat ttatggttcg
    35401 ccagtagata gtgcctatat taataactat cctgatgtct atacagaaca tgttcagttt
    35461 acagaagaac aaggagtaaa agacattaag agcttaaata aaatagctaa aaattacttt
    35521 aaaacgatca atcctggctg tgataagcct aaagtttcta ttacggttga atttgataag
    35581 ttgactgata gtgaagaagc gaaagaattt gcgaagatta gaaattatgg tctgtttgat
    35641 acatttaaaa tatatcataa aaaatataat atttatcttg aatcaaaggt tagtggacta
    35701 caatacgatt ctttatctga aaaaactttg aaattagaag caggagacat tcaagttgct
    35761 ttttatcagc aacaagctgt aactattcag gataaattaa aagattatgc aacgaataat
    35821 tatatgagtg attttaatga ttatgtttct tcaatgatta caggtcaagg cagtgcagga
    35881 ggatatgtag ttttatggcc aaaagaaaaa ccttccaaca tctttattat ggataatcca
    35941 gatttagaaa aggcaagaga agtactaaga atgaataaaa atgggattgc tttttctaag
    36001 aaaggatggc gggggccttt taattcagct tggacattag atagtatatt taatgccaat
    36061 tttatacaaa ctggattaat caaagcagat atctttcaaa attcttttaa caagactgga
    36121 gatgtattga aattagttaa tggactactc caaatttgga acaacaaaaa gaaaataatg
    36181 gagttaacta aaaaaggaat ggaattttgg aattctaagg gttcaattgg aacgattgga
    36241 acaactgatt ctgttggtaa tccttttcct ggggcttcta ctccaacccc tattgaagat
    36301 aattctttag ttattcgtac aaatggagac ggcaaatata ttttgatttc tcctaaagta
    36361 ggaaaaggat tagttttatt aggaaatggt aaagcaattt attttggaga cttagatgta
    36421 caaggaaaac ttacagttaa aggaaaagaa ataattcctg gacaaggtgg tggtccatcg
    36481 ggaggtggag aatctactgg tgggtatcct agtgaattaa aaacagatgc agaaaagaga
    36541 gcttggagaa tttacgatat tttgtgtaat aacggattta cgaaacaatc tgcatgtgga
    36601 atattgggga acattcaaca agaaacagga ggaacttttg atcctgatac tgttcaaata
    36661 ggtggaccag catacggatt agttcagtgg gatggttctt catatcctct tgttggtcca
    36721 gcaacatggg atggaaaagt ttatgttcaa aacttattta atgctgcagg tattaaagaa
    36781 ccaataacga gcttagatgc acaagttcga ttgcttattt ggacatttac aaatggacaa
    36841 tggatgg
//
LOCUS       DAZKKZ010000025        36569 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.025, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000025 DAZKKZ010000000
VERSION     DAZKKZ010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 36569)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36569)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36569
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.025"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(26..1522)
                     /gene="lysS"
                     /locus_tag="ACG8LA_001323"
     CDS             complement(26..1522)
                     /gene="lysS"
                     /locus_tag="ACG8LA_001323"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004824 - lysine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006430 - lysyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HFQ0203629.1"
                     /translation="MTQEQQHQVEDLNDQMLVRRQKMEQLREDGIDPFGKRFERTHNS
                     EELHELFDPRTKEELAEMGLTASVAGRMMTRRGKGKTGFAHLQDREGQIQIYVRKDQV
                     GDEAYEVFKHADLGDFFGVTGQIMKTDTGEVSIKASEITILSKALRPLPDKYHGLTNI
                     EQRYRQRYLDLISNRESFDRFMKRSQIISEIRRYLDGNGYIEVETPVLHNEAGGAAAR
                     PFITHHNALDIDLYLRIALELHLKRLIVGGMEKVYEIGRVFRNEGIDTTHNPEFTMLE
                     AYTAYTDFNDVMNLTEGIIRNAAEKVLGTAKITYDGQAVDLESDFKRIHMVDAIKEQT
                     GVDFWQEMTLEEALALAEKHNVEVTEAMGVGHVINEFFETFVEETLTQPTFVYGHPVE
                     VSPLAKKNPEDPRFTDRFELFIVGREFANAFTELNDPIDQRERFEAQEKERELGNDEA
                     HGVDEDFLEALEYGMPPTGGLGIGIDRLVMLLTDAQSIRDVLLFPTMR"
     gene            complement(1633..2637)
                     /gene="dusB"
                     /locus_tag="ACG8LA_001324"
     CDS             complement(1633..2637)
                     /gene="dusB"
                     /locus_tag="ACG8LA_001324"
                     /EC_number="1.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0017150 - tRNA dihydrouridine synthase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HFQ0203630.1"
                     /translation="MEHTWKIGNVEIPNRVVVAPMAGITNSAFRVTVKEFGAGLVVCE
                     MISDQGIHFRNKKTLEMLHIEETEHPLSLQIFGGNKDSLVEAAQFVEENTAADIIDIN
                     MGCPVNKVIKAEAGAKWLLDPEKVYEMVQAVSSAVNIPVTIKMRIGWDEEHVFAVENA
                     LAAQSAGASAIAMHGRTRVQMYEGKADWEVLKEVKKHLTIPFMGNGDVKTPEDAKWML
                     DYVGADGVMIGRAALGNPWMIHRTQHYLETGELIPEPTPAEKIATAKLHLQRLADLKG
                     EKVDCREFRTHAAYYLKGIPRAAKVKVAINQTEKQQEINDLLDQFVEKAEKVLLKQTL
                     "
     gene            complement(2638..3525)
                     /gene="hslO"
                     /locus_tag="ACG8LA_001325"
     CDS             complement(2638..3525)
                     /gene="hslO"
                     /locus_tag="ACG8LA_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HFQ0203631.1"
                     /translation="MKDYLVKALAHDGFVRAYAVQATNTVAEAQRRHDTWHTSSAALG
                     RTLVGSLLLGATLKGEDKLTVRIQGDGPATGIVVDANGKGDVKGYIKNPHLSLPLNSE
                     GKIDVRGAVGTQGMFTVTKDLGLKEPFSGQTPIVSGEIAEDFTYYLAISEQIPSAVGL
                     SVLVNTDDSIKTAGGFMIQIMPGADEETISKIEEQLKTTPRISTLLDEGQTPEEILKG
                     LLGTEELNILEKMPVQFKCDCSKEKFAEAIIALGAEEIQAMIDEDHGAEAVCSFCNNK
                     YKYSEEELDGLKKEALGGI"
     gene            complement(3742..5853)
                     /gene="ftsH"
                     /locus_tag="ACG8LA_001326"
     CDS             complement(3742..5853)
                     /gene="ftsH"
                     /locus_tag="ACG8LA_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HFQ0203632.1"
                     /translation="MNKKNNGMMKNALYYVLVILAMVMVVYFIFGNNGQRSSDIEYSK
                     FTEQLQAGKIKEFEVQPANGVYKITGEYKEQQTVANSGGLAILGSTDTTTTHFTTIIL
                     PNDTTLSQVTELAKENKVATTVKEESSSGIWVSLLLSFLPIVIIIFFFYMMMGQQGGG
                     GGGGGRVMNFGKSKAKEADKKANRVRFSDVAGAEEEKQELVEVVEFLKDPRRFVELGA
                     RIPAGVLLEGPPGTGKTLLAKAVAGEAGVPFYSISGSDFVEMFVGVGASRVRDLFETA
                     KKNAPAIIFIDEIDAVGRQRGAGMGGGHDEREQTLNQLLVEMDGFDGNEGVIVIAATN
                     RSDVLDPALLRPGRFDRQILVGRPDVKGREAILRVHARNKPMADDVDLKVVAQQTPGF
                     AGADLENVLNEAALVAARRNKKKIDASDIDEAEDRVIAGPAKKDRVISKKEREMVAYH
                     EAGHTIVGLVLSRARVVHKVTIIPRGRAGGYMIALPKEDQFLMTKEDMFEQIVGLLGG
                     RTAEEIIFNVQSTGASNDFEQATALARSMVTEYGMSDRLGPVQYEGNHQVFVGRDYGQ
                     TKAYSEQVAFEIDQEVRKILMEAHDKAREIIEAHRAQHKLIAEKLLEFETLDAKAIKS
                     LFEHGVMPEGTESNDYPSEKEAKTFEEAKRALEEKDAEKQAEEKRDFEEAKHELNEEN
                     KAEHDSDSQQSEDNHSDDQYK"
     gene            complement(5943..6488)
                     /gene="hpt"
                     /locus_tag="ACG8LA_001327"
     CDS             complement(5943..6488)
                     /gene="hpt"
                     /locus_tag="ACG8LA_001327"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006166 - purine ribonucleoside salvage
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HFQ0203633.1"
                     /translation="MLEKDIERILISQEEIQVRCKELGKELTEIYQNTNPLVVGVLKG
                     AVPFMADIVRSIDTYLELDFMDVSSYGNATVSSGEVKIVKDLDTNVEGRDLLIVEDII
                     DSGRTLAYLVDLFKYRKAKSVKIVTLLDKPEGRVVNIEADYVGFNVPNEFVVGYGLDY
                     AEAYRNLPYIGVLKPSVYQSN"
     gene            complement(6488..7933)
                     /gene="tilS"
                     /locus_tag="ACG8LA_001328"
     CDS             complement(6488..7933)
                     /gene="tilS"
                     /locus_tag="ACG8LA_001328"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016879 - ligase activity, forming
                     carbon-nitrogen bonds [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HFQ0203634.1"
                     /translation="MNVEKGGKKAPLLQQSFIRHGNEQGFWQQGSRILAAVSGGVDSM
                     VLLHLLLQVQRQIGFSLGIVHINHQLREESAEEAAYLRSYCEEKNLPLYVSIWEDPAK
                     SAIETEARNFRYQEFTRVMEEGQYDTLMTAHHGDDQIETVLMKIVRGGQLNTFSGIKE
                     VQPFATGRLIRPLLSFSKEDLYTYAAESQLVYFEDQTNQLLDIQRNRLRHLVVPQLKQ
                     ENTQALRHFQQFSQQIQWADQVIQKYMGQLIEKEVEQWEEQFRFSAEMIEEMTDAERY
                     YFFYSFFDKAFSKTGIILKEQQMESILDQWQQKKSQWQLSIGNNWILKREYHFVVLSK
                     KEKQATSQTEDQRLLLIPEQGIYLNETEWIGLVKPENAGDIKATDSWSLFSHDIWIPA
                     DVQLYVEKRKAGDRIKLTENLTKKVSRYFIDQKVPNSQRQHAWIITDAKRNIYSLIPF
                     AFSYLSIREETDKIHYILLYKYQKEAIGRRT"
     gene            complement(8053..8523)
                     /locus_tag="ACG8LA_001329"
     CDS             complement(8053..8523)
                     /locus_tag="ACG8LA_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S1 domain-containing RNA-binding protein"
                     /protein_id="HFQ0203635.1"
                     /translation="MSIEVGAKLQGKVSGITNFGAFIDLGAGKTGLVHISEVSNGYVK
                     DIHDVLSVGDEVTVKVISVNDDGKIGLSIRKAQEQPAESGEESRPKKYQQKDPRDNRN
                     RPAQKKSFSRSQPSAQKEDFDSLMSSFLKDSDDRLSSLKRNTEGKRGGRGGRRS"
     gene            complement(8569..8994)
                     /locus_tag="ACG8LA_001330"
     CDS             complement(8569..8994)
                     /locus_tag="ACG8LA_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HFQ0203636.1"
                     /translation="MTKKSNKIAALDTEYAKKKYAEFQQQQRQLIFRRRRLAAIFVGA
                     LVIFAIIGVQIFHDMQRMHQLNELRVEANTEMKEVNADVDQLHQDVSLLKDDEYVAKL
                     ARSKFFYSKDGEKVYPILESNTDSSTNETDQSTSSTTAK"
     gene            complement(9061..9330)
                     /locus_tag="ACG8LA_001331"
     CDS             complement(9061..9330)
                     /locus_tag="ACG8LA_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HFQ0203637.1"
                     /translation="MRLDKFLKISRIIKRRSVAKEVADKGRIQINGKLAKSSSDVKVG
                     DILKVQFGNKTLEVKITELHESTKKEDAQKMYEIISENRTETLEK"
     gene            complement(9341..10936)
                     /locus_tag="ACG8LA_001332"
     CDS             complement(9341..10936)
                     /locus_tag="ACG8LA_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HFQ0203638.1"
                     /translation="MDHKEMRRVMQGAFVLTIASFIAKVLSALYRIPLQNLVGDEGFY
                     VYQQVYPIYGIAMTLALSGLPQFISKYVAERKNPFERKQALQNLYPLVFWTGVFLWLF
                     VFAFSSWIAWMMGDIQLKPLIQVVSFTFLLMPGLSFYRGNFQGRFLMEPTAVSQVVEQ
                     FVRVFVIVCSAFAFRKLGWTVYQTGTAAMSGAVFGGLCAYGILHYYEQKIHGGALSFR
                     RFPLFKQPSKPLIRRFLVEGGLVSIYSGLLIFFQLIDSFFVKNALEVYGLSEYGAKIA
                     KGVYDRGQPLVQLGLVIATALSATFLPALTRHLTNRIYRQFLQTAKIYLRLTTALALA
                     ASLGLALLLPYINYALFKDYAGNAALVLFVFSIAFTAVIQAYQSIAQSKNSFRPSLKG
                     AGWGLLVKGLTTSFLTGLLGTAGASLSTLLGLGVTLWYFVRIETKELNAFWKERHFGR
                     KLMFSLLCMTVVLLLYYGVLNIVFGPVTHRSTAFFVSVIGVGIGASVFIYAVIRLRLF
                     TVREWLMLPFGKKILRLNKKIKK"
     gene            complement(10951..14472)
                     /gene="mfd"
                     /locus_tag="ACG8LA_001333"
     CDS             complement(10951..14472)
                     /gene="mfd"
                     /locus_tag="ACG8LA_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HFQ0203639.1"
                     /translation="MDIIQLVGKDPQVKEWVSNLEEKMPRQLITGLAGSAKTLLFARA
                     FKKTNKNMIILMPNLYYANQLAEDLQHVIPQDQIHLFPVDEVLSAEMAFSSPEARGER
                     VATLNALQEKKAGIYLLPVASLHKRLPNKKTWLQAQLNWHIGDEIDVENLPRQLTLMG
                     YVREEMVAKPGEFSIRGSIIDIYPLTTTYPVRVELFDVEIDSMRYFEAETQRSIEKTE
                     EIWVSPTSEQVYGPEDLEHGIEQMQKMLEKRLAATTEEADREFLQDYFGQLTSSWQAG
                     VPTEEAKFYSDLLYQESVTILDYFPSNSLLVVDDYQRIMETNREIEREAAEWQTQKIS
                     ELRVFSEQTFSADIQKIVQKEKFTTTFFSLFQKGMGNLRFQAIHNFQYRTMQQFFGQM
                     PLLKTEMDRWRKQKQTVVIFIPTKDRIRKAEQMLRDEDILVVETEKNALIRGQVQLVE
                     GALQAGFELPQEKIVAITEKEIFQKTTKKQTRRQTVTNAERLKSYNELKAGDYVVHAN
                     HGIGKYIGMETLEVDGVHQDYMTILYQNDDKLFIPVTQLNLIQKYVASEAKAPRINKL
                     GGSEWTKTKRKVSSKIEDIADDLIKLYAARESEKGYAFGPDDAYQKEFENAFPYSETD
                     DQLRSAAEIKRDMEKEKPMDRLLVGDVGYGKTEVALRAAFKAIKESKQVAFLVPTTIL
                     AQQHYETMLERFEGFPVNIGLLSRFRTRKQQKETIEQLRTGQVDIVVGTHRILSKDIE
                     FSDLGLLIIDEEQRFGVKHKERLKQLRAQVDVLTLTATPIPRTLHMSMLGVRDLSVIE
                     TPPANRYPIQTYVMEKNPGAIREAIHREMGRGGQVFYLYNRVETIEQKVEEIQELVPE
                     ARIGYAHGQMTEAQLENTLFEFIEGQYDVLVTTTIIETGVDIPNANTLFVENADYMGL
                     STLYQLRGRVGRSSRVAYAYFMYEQQKILNEVSEKRLQAIKDFTELGSGFKIAMRDLS
                     IRGAGNLLGAQQHGFIDAVGFDMYSQMLSEAVSRKQGKNSQVEKTTVEIDLGVDAYLP
                     ETYVADQRQKIEIYKRIRELDSQEMLDELEDDLLDRFGEYPEEVAHLLTIGQIKMDGD
                     RALLETIRKQEAHIVFTLSKVGTKRYSVEQLFEALTATKLKASLGVEKEQMVIRLTIP
                     NQMEEAVWLQEIQKFVKALREQKYLSA"
     gene            complement(14489..15049)
                     /gene="pth"
                     /locus_tag="ACG8LA_001334"
     CDS             complement(14489..15049)
                     /gene="pth"
                     /locus_tag="ACG8LA_001334"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004045 - aminoacyl-tRNA hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HFQ0203640.1"
                     /translation="MKMIVGLGNPGTKYQYTKHNIGFMVVDKIAREHQATFKKNPFEA
                     EVAEFFHNGEKILLVKPQTFMNESGRAVGPLMTYFGIYPEELVVIYDDLDLAVGKIRL
                     RQKGSAGGHNGIKSIISHLNTNVFDRIKVGIGRPEGKKTVVQHVLSPFSKENQPLIEE
                     SMCQSVKAVEYLIEGHSFVDAMNRFN"
     gene            15402..16376
                     /locus_tag="ACG8LA_001335"
     CDS             15402..16376
                     /locus_tag="ACG8LA_001335"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004459 - L-lactate dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HFQ0203641.1"
                     /translation="MTAAAEKKDHQKVILVGDGAVGSSYAFALVTQNIAQEVGIVDIN
                     TAKTEGDAIDLSHALAFTSPKKIYSATYADAHDADLVVITAGAPQKPGETRLDLVNKN
                     LKINRDVVTQIVESGFNGIFLVAANPVDILTYSTWKFSGFPKERVIGSGTSLDSARFR
                     QALAELVDVDARNVHAYILGEHGDSEFPVWSHANVAGLQIYEWVKNNPEIDEEAMVNL
                     FFGVRDAAYTIIEKKGATFYGIAVALARITRAILDDENAVLPLSVFMNGEYGLNDIYI
                     GAPAVINRQGIQKVIEIPLSDSEQDRMAASAKQLKEILDEAFAKLDAE"
     gene            16546..17946
                     /locus_tag="ACG8LA_001336"
     CDS             16546..17946
                     /locus_tag="ACG8LA_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase family protein"
                     /protein_id="HFQ0203642.1"
                     /translation="MTRSSHRKKSKHVALLSVLGVLLVLISFYTYRSTYYTKHFLPNT
                     EINGINVSNLTVEKANEKLKEAYSDKKLAIKEDGKVWQEVPKSELGYKDDFTSELSPI
                     LNEQNGWTWGMTYVSAAEKQEIDPVSQNHQKLDTTVQTLTTKLTDLNKDRTPTTDATI
                     EKAGDSFVIKPEVNGNTIDVDAAVKQLKSAVNSGKDTIELTEFKEKPKVTSEDSSLKE
                     QLASMNAIANVKATYSINGETFQIPSSDIMSWLTYNDGKVDLDTEQVRQYVTDLGTKY
                     NTSTNDTKFKSTKRGEVTVPVGTYSWTIQTDSETEALKKAILAGQDFTRSPIVQGGTT
                     ADHPLIEDTYIEVDLENQHMWYYKDGKVALETDIVSGKPTTPTPAGVFYVWNKEEDAT
                     LKGTNDDGTPYESPVNYWMPIDWTGVGIHDSDWQPEYGGDLWKTRGSHGCINTPPSVM
                     KELFGMVEKGTPVLVF"
     gene            complement(18024..18746)
                     /locus_tag="ACG8LA_001337"
     CDS             complement(18024..18746)
                     /locus_tag="ACG8LA_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFQ0203643.1"
                     /translation="MSGHSKWHNIQGRKNAQDAKRGKVFQKLSREIYMAAKAGGPDPS
                     MNPALRLVVDKAKAANMPNDNVERAIKKATSAVDETNYDEITYEGYGPGGVGILVHAL
                     TDNRNRTATNVRVAFTRNGGSLGETGSVSYLFDRKGYIAIERDGLTVDEETMFEDVLE
                     AGAEDLQTSPEVFEIYTAPEDFAAVRDELEKEFTLAQAELTMIPQTTIDLNEEQKEQL
                     ERLVDKLEDDDDVSEVFTAAEM"
     gene            complement(18825..19331)
                     /locus_tag="ACG8LA_001338"
     CDS             complement(18825..19331)
                     /locus_tag="ACG8LA_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HFQ0203644.1"
                     /translation="MNSSKKQMKNGNIYLVIALIVVIILFYSSSQTYGQQSQVSRLES
                     WLPNQPFKDTLAGIRFNYGGSMVSIDHLGYAKFLEFFLRKGAHFGTYFILGGSLFLGV
                     FPKLKIWWLTAILAWLSATGYAGLDEFHQMMTGGRTPMFQDVMLDSIGALTAVILCVL
                     FAAFKKRL"
     gene            19454..21253
                     /locus_tag="ACG8LA_001339"
     CDS             19454..21253
                     /locus_tag="ACG8LA_001339"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M3 family oligoendopeptidase"
                     /protein_id="HFQ0203645.1"
                     /translation="MSYSLNWNLDSIFSGGSHSDALNQRMKQLEDQMNEYYHRVTKWS
                     PSSDNAEQLNAILQLQETITNGFTQCSSYITALLSANVNDSDAKVLSGKLYAMLPRLQ
                     SAETVLSKKFAEISDNDWNQMLSQSSFETIAFRLNEIRRDGSQLLSEAEENIINTLSL
                     DGLNAWSSHYDTIVASISIPFEQDGQVVELSAGQAFNKMMGDPDPKVRETLFAAWEEA
                     WKEKAPLFTDTLNHLDGFRLSDYELHGVTDFLQKPLEYNRLKKETLSVMWDTIQKNKQ
                     PLVNYLTRKANLFGKEKMEWQDQDAPIILGDLKEKTFSFDEAAAFIIENFNKFSPKMA
                     KFAQSAFEKSWIEAEDRPGKRPGGYCTELPETKESRIFMTYSNSVNEVATLAHELGHA
                     FHSSTMWDLPSLNREYAMNVAETASTFAELIVADATLKVAKTKEEKINLLDTKLQNAL
                     AMFMNIHSRFIFENRFYEARQEGLVSEDKITEMMVEAQKEGYQGALATYHPYFWAAKL
                     HFFIDDVPFYNFPYTFGYLFSLGIYAYANQKGANFEEEYIHLLRDTASMTTEDLAKKH
                     LNVDLTQPDFWQAGIDMVTEDIQTFMELTEEFI"
     gene            complement(21321..22895)
                     /locus_tag="ACG8LA_001340"
     CDS             complement(21321..22895)
                     /locus_tag="ACG8LA_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NlpC/P60 family protein"
                     /protein_id="HFQ0203646.1"
                     /translation="MKKSLISAVMVCSMTLTAVASPIAAAADDFDSQIQQQDQKIADL
                     KNQQADAQSQIDALESQVSEINTQAQDLLAKQDTLRQESAQLVKDIADLQERIEKRED
                     TIQKQAREAQVSNTSSNYIDAVLNADSLADAIGRVQAMTTMVKANNDLMEQQKQDKKA
                     VEDKKAENDAKLKELAENQAALESQKGDLLSKQADLNVLKTSLAAEQATAEDKKADLN
                     RQKAEAEAEQARIREQQRLAEQARQQAAQEKAEKEAREQAEAEAQATQASSTAQSSAT
                     EESSATQSSMTEESSSATQSSATEESTTPESSTEESTAPESSATEESTTAPESSATEE
                     STTVPESSATEESTTVPESSTTEESTTPAPTTPSTDQSVDTGNGTGSSTPAPTPTPTP
                     EQPKPVTPAPAPSGSVNGAAIVAEAYKYIGTPYVWGGKDPSGFDCSGFTRYVYMQVTG
                     RDIGGWTVPQESAGTKISVSQAKAGDLLFWGSQGGTYHVAIALGGGQYIHAPQPGESV
                     KVGSVQWFAPDFAVSM"
     gene            complement(23150..23659)
                     /gene="mreD"
                     /locus_tag="ACG8LA_001341"
     CDS             complement(23150..23659)
                     /gene="mreD"
                     /locus_tag="ACG8LA_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HFQ0203647.1"
                     /translation="MLKKETMKYYLPIVLFFLMLIDGHLTRMLGEWSKGTYMSNAHFL
                     ILALLCCSMAFEKRYLLITTIVLGAIYDAYYIGVIGIYAVALPLIVWLMYVMKDVIHV
                     NIFTEFFSMIIFVTGYELFTMVVQLIFKLAVVNNTYFITRFLGPTLLLNMIIFVLFIF
                     PFKKLFSDE"
     gene            complement(23663..24517)
                     /gene="mreC"
                     /locus_tag="ACG8LA_001342"
     CDS             complement(23663..24517)
                     /gene="mreC"
                     /locus_tag="ACG8LA_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HFQ0203648.1"
                     /translation="MKKFNPNKNIIITLVIVIIVVTILSVTAAQRANEGKPNFFQSIV
                     NDSVAMVDKTISAPVRWVRNGVDSVHNLFSTYAENERLKEKIDSYDDVSQQNKNYERE
                     IEALKKELELNQTLTSYEKVTANVITRSPDSWQDMLIVDKGSKDGIEANMAVMSQKGL
                     IGRVIEVNTASSKIELLSSSNESSNHFPVRVSSANGEAFGLLKNYDEKLHALVVTQLT
                     GDTDIKEGDVVQTSGLGGNSPANLPIGTVIKTKPDSYGLDREVYVKPYAEMYDVSVVT
                     IVQRLAED"
     gene            complement(24672..25310)
                     /locus_tag="ACG8LA_001343"
     CDS             complement(24672..25310)
                     /locus_tag="ACG8LA_001343"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004788 - thiamine diphosphokinase
                     activity [Evidence IEA];
                     GO_process: GO:0006772 - thiamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HFQ0203649.1"
                     /translation="MKILLAAGGNPQNWPQSLLSKYDAYVGIDRGALYLLQAGYPVDL
                     AVGDFDSLSNEEQKEVFAKAKEYTRSPAEKDDTDTQLGILKTFERYPQAEVTLIGATG
                     GRLDHLLANLWLGMEPRFKPFAHQLIIRDCQNYLSYYLPGEHIVRQIPDMKYLAYCCL
                     TPVSNLTLKGSKYVLENKEVEYPTSYASNEFLSDTAEFSFSDGMIAVIQSKD"
     gene            complement(25311..25961)
                     /gene="rpe"
                     /locus_tag="ACG8LA_001344"
     CDS             complement(25311..25961)
                     /gene="rpe"
                     /locus_tag="ACG8LA_001344"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004750 - D-ribulose-phosphate 3-epimerase
                     activity [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HFQ0203650.1"
                     /translation="MKIAPSILSADFANLQRDIELVEKGGADYIHVDVMDGQFVPNIT
                     LGPNIVQAIRPVTKLPLDVHLMIVDPENYIPAFAKAGADIITVHVEATPHIHRALQMT
                     KSLGVKAGVVINPGTPVSMIKHVLPLADQVLVMTVNPGFGGQSFIEETVEKITELADL
                     RRENNWTYAIEVDGGIVPETAKICKDAGADVFVAGSYIYGAENPVGQIERLKEALD"
     gene            complement(25974..26873)
                     /gene="rsgA"
                     /locus_tag="ACG8LA_001345"
     CDS             complement(25974..26873)
                     /gene="rsgA"
                     /locus_tag="ACG8LA_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HFQ0203651.1"
                     /translation="MALIKGQIRKAISGFYYVYANGETYQTRGRGNFRNRKITPLVGD
                     QVIFESENQTDGYLLEILPRKNQLVRPPVTNVDLGIIVTSIVEPAFSYNLLDRFLVTL
                     EYESIEPIIFLTKTDLSDDPEKIEEIKQTYTKIGYPVIVPNHTGDTTELIRYFPERLS
                     VFMGQSGAGKSTLLNQISPELNLATGEISDALGRGRHTTRHVELIPIYGGLVADTPGF
                     SSIDFLTIEAGELPRQFPEFVEASVHCKFRECMHAKEPGCEVKHRVETGGIAQTRYDN
                     YLQFLQEIEKRKPMYAKKEGKRK"
     gene            complement(27038..29107)
                     /gene="pknB"
                     /locus_tag="ACG8LA_001346"
     CDS             complement(27038..29107)
                     /gene="pknB"
                     /locus_tag="ACG8LA_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004672 - protein kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HFQ0203652.1"
                     /translation="MIELGKKLNGRYQITGNIGSGGMANVFLAHDLILDRDVAVKVLR
                     FDFQNDQTAIRRFQREALAATELVHPNIVSVYDVGEEDNMQYLVMEYVKGMDLKRYIQ
                     THYPVPYETAVNIMQQILSAISLAHNHQIIHRDLKPQNVLIDNEGVVKITDFGIAIAL
                     SETSITQTNTMLGSVHYLSPEQARGSMATKQSDIYALGIILYEMLTGSVPFDGESAVT
                     IALKHFQDDLPSIKALDPNVPQALENVILRATAKEPADRYKSAEEMSDDLSTVLSPAR
                     ANEEKWQPHVMDNETKVITPLTEDAPMPDSFKSMPLPKDKPENETLPEEEEVLPDPKK
                     KGQKKWWLILLAILAVLGIGTAVFFASGGRGEVVVPDVSDLSEASARETLAKAKLEVA
                     TKTEEIADDKIEEGNVVKTDPAAGTTVKQKREVTLYISSGTKKIKLDDYSGKSYEDAE
                     ASLKELGFSADLIQKEEEFSSEVESGMIISQSPSEDTEVDPKTDTITFTVSKGPETVT
                     LSSHVGENYETVRNWLVTQGFNINNISATYDYSDTVPSGSIISQDPASGEVVAEETYI
                     NFVVSQGTEPKLNDISGYTKSEAQSYLASVGAEYIGHETSEYSNTVDKDKVIRTVPGA
                     GTTITKGMVVNVIYSKGPDPASSSSEKDSSDSSSSSSSSSSTSNSSKEESSSSTSSSA
                     STSESSK"
     gene            complement(29104..29844)
                     /locus_tag="ACG8LA_001347"
     CDS             complement(29104..29844)
                     /locus_tag="ACG8LA_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004722 - protein serine/threonine
                     phosphatase activity [Evidence IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HFQ0203653.1"
                     /translation="MQIEYQSDVGRRRNTNQDYASVFTSRSGLKLAVLADGMGGHRAG
                     DIASQMAVTNLGEAWEKQEAVDDEKIAQWFIQSIQEENMLIYQRGQEQPEYNGMGTTI
                     VAAALSDDWFTIANVGDSRAYLIREDKIMQLTEDHSLVNELVKSGEISEEMAVNHPRK
                     NILTRSVGMPGTVEVDVSTHLWQLKDRLLLCSDGLTNMLSEEEIGTIINQEGPLSHKV
                     TELIDRANEAGGADNITVLLIEYKEDSV"
     gene            complement(29857..31215)
                     /gene="rsmB"
                     /locus_tag="ACG8LA_001348"
     CDS             complement(29857..31215)
                     /gene="rsmB"
                     /locus_tag="ACG8LA_001348"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0001510 - RNA methylation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HFQ0203654.1"
                     /translation="MKKIPKKMKKSVRYMALLTLERVNKGGAYSNLLLNEMIKQSELN
                     QKDVGLFTELIYGTISHQRLLEFYVAPLIAKAKKVDDWVKTLLYLSVYQLEFLDKVPA
                     HAILNEAVEIAKVKGNPGTGKFVNGVLRNYQRQGAPDLQGIADPIERLSVKISLPLWM
                     TKRLVDQIGYEETEKLGLSLYQPSHASARVDTRRLSRDQAITVLQEEEITAEKSQVSP
                     YGIVAKKGHLASSSLFHDGVMTIQDESSMLVAPSMQIEPEHHVLDACAAPGGKTTHIA
                     SFLDPSCGGEVVALDVHEHKVKLIEDNAARLGVSSAVYAQKMDAREVSKQFEAEQFDR
                     ILVDAPCSGLGLLRRKPDIRYKKQPDELANLPKIQLEILESCAPTLKSSGILTYSTCT
                     ILKEENQDVVSAFLERHPDFERIDVLTNPMLQSSIEEKMLTLYPHQFYTDGFFICCLR
                     KK"
     gene            complement(31215..32153)
                     /gene="fmt"
                     /locus_tag="ACG8LA_001349"
     CDS             complement(31215..32153)
                     /gene="fmt"
                     /locus_tag="ACG8LA_001349"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004479 - methionyl-tRNA formyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0071951 - conversion of methionyl-tRNA to
                     N-formyl-methionyl-tRNA [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HFQ0203655.1"
                     /translation="MTKLVFMGTPAFSVPILEGLIESGYEIQAVVTQPDRPVGRKRVI
                     TPTPVKEAALKHGIRVLQPEKISGSPEMEEIIELVPDVIVTAAFGQFLPEKLLQVPKL
                     GAINVHASLLPKYRGGAPVHYAIMNGEKETGVTIMEMIKKMDAGGIYAQESIPITKQD
                     DVGTMFEKLSLLGRKLLLETLPNILDGQKPVPQDESEATFSPNITREQEAIDWHKTAE
                     EIDNQVRGMRPWPIAFTTYEGIRWKLLSVEVLAETTDKAPGTIIRKDKKNLWIACGKQ
                     TVLAINELQPAGKGKQAVHDFLNGSGQQVQIGQQVK"
     gene            complement(32146..32637)
                     /gene="def"
                     /locus_tag="ACG8LA_001350"
     CDS             complement(32146..32637)
                     /gene="def"
                     /locus_tag="ACG8LA_001350"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042586 - peptide deformylase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HFQ0203656.1"
                     /translation="MRYPILIHPNDKLKRTAQPIDVITDETIALLDNLYETMIANDGI
                     GIAAPQVGQNKRIAVIEVDEGEKFELINPEIIEAKGESLDVEGCLSIPHVYGTVKRAD
                     EVTVRYYDRDGEEIEVTAFGYLARAFQHEIDHLDGILFIEKMIQQIPEEELEEYMEEH
                     LDD"
     gene            complement(32652..35060)
                     /gene="priA"
                     /locus_tag="ACG8LA_001351"
     CDS             complement(32652..35060)
                     /gene="priA"
                     /locus_tag="ACG8LA_001351"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0032508 - DNA duplex unwinding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HFQ0203657.1"
                     /translation="MTLTAEVIVDVPTMQTDQPFTYLVPSEMETALQVGMRVEVPFGN
                     GNRHVQGFVMAIQKSEESANPSLKAVIRLLDLAPVVNEELLSLADYMKKITYAFKITC
                     LQTMLPSVMKAEYDKLIYPLADTPEVQVLFDQREVISWKEAEEEGSLSQLIRWRQEQL
                     VDIKYEVHTRNKVKTIRLVRSLLTEKQIEEEWAKLRQNAKKQKELLLCLSELSQEEPI
                     AYFKNKGISTAVLNQGKEKGWLEFIESERYRDPYKDRVFDQTTALELNAEQKNAVEQI
                     ITAGQQQKDQVFLLEGITGSGKTEVYLQAIADVLSENKTAIMLVPEIALTPQMVERFK
                     GRFGESVAVLHSGLSQGEKYDEWRKIEREEAQVVVGARSAIFAPLKNIGLIIIDEEHE
                     SSYKQDETPRYHARDLAIWRSKYHHCPIVLGSATPSLESRARAQKGVYQLLQLNHRAK
                     AAAQLPAIEIVDMREEFQNHRTSTFSANLQEKIQNRLDKKEQTVLLLNRRGYSSFVMC
                     RDCGFVLPCPNCDISLTLHMDTRSMRCHYCGHEEPIPNRCPNCGGNKIRYYGTGTQKV
                     EEELRELYPQARILRMDVDTTRRKGAHEQILQKFGAKEADILLGTQMIAKGLDFPEVT
                     LVGVLNADTSLNLPDFRSSEHTFQLLTQVSGRAGRAEKAGEVVIQTFNPQHYAIELAK
                     KQNYEQFYQQEMHVRHRGGYPPYYFTVKITASHPEEQVAAKKIFQIANQLKEVLSPQS
                     LLLGPTPSMILRVKNRYYYQLIIKYKHEPNLPHVLDEILNGSQKEQRQGLFVAIDNEP
                     LNFI"
     gene            complement(35313..35618)
                     /gene="rpoZ"
                     /locus_tag="ACG8LA_001352"
     CDS             complement(35313..35618)
                     /gene="rpoZ"
                     /locus_tag="ACG8LA_001352"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HFQ0203658.1"
                     /translation="MMLKPSIDSLLDRVNSKYSLVILASKRAHELDASAQPTLDSFDS
                     VKSVGQALEEIDAGNVVNDPHPELKRERLKMEEEERQAQKEREQHELESRIREEQKM"
     gene            complement(35623..36237)
                     /gene="gmk"
                     /locus_tag="ACG8LA_001353"
     CDS             complement(35623..36237)
                     /gene="gmk"
                     /locus_tag="ACG8LA_001353"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010766465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004385 - guanylate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006163 - purine nucleotide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HFQ0203659.1"
                     /translation="MSERGLLIVLSGPSGVGKGTVRKAIFESEDNDFQYSISMTTRKM
                     REGEVEGVDYFFRSKEEFESMIEAGEMLEYAEYVGNYYGTPLSYINKTLDEGKDVFLE
                     IEVQGAKQVKEKVPDGVFIFLTPPDLAELKSRIVGRGTDADEVIEERMKVAKEEIEMM
                     ALYDYAVVNDEVPLAVERIKNIIASEHFRVDRVIGKYIKMLKEM"
BASE COUNT         9886 a         7988 c         6705 g        11990 t
ORIGIN      
        1 aattccttag acagctttta ttcgattatc tcattgttgg gaatagcaaa acatcccgaa
       61 ttgattgtgc atcagttagc aacattacta atctgtcgat cccgatgcct agaccaccag
      121 ttggcggcat accgtattct aaggcttcca agaagtcttc gtctacaccg tgagcttcgt
      181 catttcctag ttcacgttct ttttcttgcg cttcgaatct ttctctttga tcaattggat
      241 cgttcagttc tgtaaaggca ttagcaaatt cgcgccccac tatgaatagt tcgaatcgat
      301 ctgtgaatcg aggatcttct ggatttttct tcgctaaagg cgaaacttcg actggatgtc
      361 cgtatacaaa cgtcggttgt gtcaatgttt cttcaacaaa tgtttcaaag aattcattga
      421 taacatgtcc gacacccata gcttcggtta cttctacatt gtgtttttcg gctaaagcta
      481 atgcttcttc caatgtcatt tcttgccaga agtctacacc agtttgttct ttgattgcat
      541 ctaccatatg gatgcgttta aagtcacttt ctaagtcgac agcttgtcca tcatatgtga
      601 tttttgctgt tcctagtact ttttcagctg cgttacggat aataccttct gtcagattca
      661 ttacatcatt gaaatcagta tatgctgtgt atgcttctaa catcgtaaat tctggattat
      721 gtgtagtatc aattccttca ttacggaaaa cgcggccgat ttcataaact ttttccattc
      781 cgccaacaat tagtcgtttt aaatgaagtt ctagcgcaat acgcaaatat aaatcaatgt
      841 ccagtgcatt atgatgcgtg ataaatgggc gtgcggcagc tccacctgcc tcattgtgca
      901 atactggtgt ttctacttca atatagccat tgccatctaa atagcgacgg atttcgctga
      961 taatttggct tcgtttcata aatcggtcaa agctttcgcg attactgatt aaatccaagt
     1021 agcgttgtct gtagcgttgt tcaatattcg ttaagccatg gtatttatct ggcagtggac
     1081 gaagtgcttt tgacaaaatc gtgatttctg aagctttgat agaaacttcg cctgtgtctg
     1141 ttttcatgat ttgtccagtt acaccaaaga aatctccaag gtctgcatgt ttgaatactt
     1201 cataggcctc atcacctact tggtcttttc ttacataaat ttgaatttgg ccttcacgat
     1261 cttgtagatg cgcaaatcca gttttccctt ttcctcggcg agtcatcata cgaccagcta
     1321 cactagcggt caatcccatt tctgctagtt cttcttttgt tcttggatca aatagttcat
     1381 gcaattcttc tgagttgtgc gtgcgttcaa atcgttttcc aaatggatcg attccatctt
     1441 cacgcaattg ttccattttt tgacgacgta caagcatttg atcatttaaa tcttctactt
     1501 gatgttgttg ttcctgtgtc acaaaagttc ctccattctc atgttaatct ctttcctata
     1561 atgccaatga aacacaaaaa aagcaagccg aacttggaat ttcggcttga aaattcacga
     1621 aaaacttaga aatcacaacg tttgtttcaa tagtactttt tccgcttttt ctacaaattg
     1681 atccagcagg tcattgattt cttgctgttt ttctgtctga ttgattgcta ctttcacttt
     1741 cgctgctcga ggaatccctt ttaaataata agccgcatgt gttctgaatt ctctacaatc
     1801 tactttttct cctttgagat ctgctaagcg ttgtaaatga agtttagctg tagcaatttt
     1861 ttcggctggt gttggttcag gaatcagttc tcctgtttcg agataatgct gtgtgcggtg
     1921 aatcatccat ggattgccca gcgctgcacg accaatcatc acaccgtctg caccgacata
     1981 gtcaagcatc cattttgcat cttctggcgt tttgacatcc ccgttcccca taaatgggat
     2041 cgtcaaatgt tttttcactt ctttcaatac ttcccagtcc gcttttcctt catacatctg
     2101 aacccgtgta cgtccatgca tagcgatggc acttgctcca gctgattgtg ctgctaatgc
     2161 attttctaca gcaaagacgt gctcttcatc ccaaccaata cgcatcttga ttgttactgg
     2221 gatatttact gctgaagaaa cagcttggac catttcgtat actttctcag gatctaaaag
     2281 ccattttgct cctgcttctg ctttgattac tttatttact ggacagccca tattgatatc
     2341 tattatatcg gcagctgtgt tttcttcgac aaattgagca gcttcaacta gactatcttt
     2401 atttccgcca aatatctgta aacttaatgg atgttctgtt tcttcaatgt ggagcatctc
     2461 taaagttttt ttgtttctga aatgaatacc ttggtcactg atcatttcac atacgactaa
     2521 gcccgcacca aattctttga cagtgactcg aaatgctgaa tttgttattc cagccatcgg
     2581 tgcaacaacg acacgattag ggatttccac attgccaatt ttccatgtgt gttccactta
     2641 aatccctcct aaggcttctt tcttcaatcc atctaattct tcttcgctat acttgtattt
     2701 gttattacag aaagaacaaa ccgcttctgc accgtgatct tcgtctatca ttgcttggat
     2761 ttcttctgca cctaacgcga taattgcttc tgcaaatttt tcttttgaac agtcacattt
     2821 gaattgaaca ggcatttttt ccaaaatgtt caattcttct gtaccaagca atcctttcaa
     2881 tatttcttct ggtgtctgtc cttcatctaa gagggtagag attcttggtg tcgtttttaa
     2941 ttgttcttcg atcttgctga ttgtttcttc atcggcacct ggcatgattt ggatcatgaa
     3001 tcctcccgcc gtcttgatgc tgtcgtcagt attgaccaat acactcagtc caacagctga
     3061 agggatttgt tctgagatag caagatagta agtaaaatct tcagcgattt ctccagaaac
     3121 aatcggcgtt tgcccagaaa aaggttcttt taatcctaag tcttttgtga cagtaaacat
     3181 tccttgtgtt ccaactgctc cccgcacatc gattttacct tcactattta gaggaagact
     3241 gagatgcgga tttttgatgt aacctttcac atctcccttt ccatttgcat ctactacaat
     3301 tcctgttgct ggaccatcgc cttggattcg aacagttagt ttgtcttctc ctttgagcgt
     3361 cgcaccaagt agcagactac cgaccaatgt ccgtcccaaa gcagctgagg aggtgtgcca
     3421 agtatcatga cgtctttgtg cctccgctac ggtatttgtt gcttgaacgg cgtatgctcg
     3481 gacgaatccg tcgtgagcaa gtgccttaac caaataatct ttcatttgtt atgtactcct
     3541 ttttccgttt ttaaactcat agtgaatcat actagcaact actgcttttt tcaactttgg
     3601 aatgcttctt ttaaaaataa ttcagaatca tctagaaaac aggacatcac cctatttaca
     3661 acttaaataa agaaatctcc cgaaaaccgg tttttgttcc ggttttcggg agtcatatca
     3721 gatcaattga cctatatttt tttatttgta ttgatcgtct gaatgattat cttctgattg
     3781 ttgagaatct gaatcatgtt ctgctttatt ttcctcattc agttcatgtt ttgcttcttc
     3841 aaaatcacgt ttttcttccg cttgtttttc agcgtctttt tcttccaaag cacgttttgc
     3901 ttcttcaaaa gttttcgctt ctttttcgct tggataatca tttgactcag taccttcagg
     3961 catcacaccg tgttcaaaca atgacttgat tgctttggca tccaatgttt cgaattccaa
     4021 aagtttttca gcaatcagtt tatgctgtgc acgatgagct tcgatgattt ctcgagcttt
     4081 atcatgagct tccatcaaga tttttcgtac ttcttgatca atctcgaaag cgacttgttc
     4141 cgagtaagct tttgtttgac catagtcgcg gccaacaaac acttgatggt ttccttcata
     4201 ttgaacagga cctaaacgat cactcattcc atattctgtt accatgcttc gtgctagagc
     4261 tgtcgcttgc tcaaagtcat tggaagcacc agttgattgg acattgaaga tgatttcttc
     4321 agctgtacgt ccaccaagta agcctacgat ttgttcaaac atatcttctt tcgtcatcaa
     4381 gaactgatct tcttttggta aagcgatcat atatccgccg gcgcgtccgc gagggatgat
     4441 cgttactttg tggacgaccc gagcgcgact caatactaat ccgacaatcg tatgaccagc
     4501 ttcgtgataa gcaaccattt cgcgttcttt tttgctgatt acgcgatctt ttttagctgg
     4561 acctgcaatc acgcgatctt ccgcttcatc gatatcagaa gcatcgattt tctttttatt
     4621 tcttctagca gctactaacg ctgcttcatt caagacattt tctaaatctg ctccggcaaa
     4681 acctggtgtc tgttgagcca caactttcaa gtcaacgtca tctgccatcg gtttattccg
     4741 tgcatggact cgcaagattg cttcacgacc ttttacatct ggacgtccaa ctaaaatctg
     4801 gcggtcaaaa cggcctggac gtagtaacgc tgggtctagt acatcagaac ggttggttgc
     4861 agcaatgacg attactcctt catttccgtc gaagccatcc atttctacaa gcaattggtt
     4921 caatgtttgt tcgcgttcat catgtccgcc gcccataccg gcaccacgtt gacgacctac
     4981 cgcatcaatt tcatcaatga aaatgatagc tggtgcgttt ttcttcgctg tttcaaacaa
     5041 atcacgaaca cgacttgctc caacaccgac aaacatttct acgaaatcag aacccgagat
     5101 cgagtaaaac ggtactccag cttctccggc aacagctttt gctaataagg ttttacctgt
     5161 tcctggaggt ccttctaaaa gtacacctgc cgggatacgg gcacctaatt caacaaatcg
     5221 gcgaggatct ttcagaaatt caacaacttc aactagttct tgtttttctt cttccgcacc
     5281 cgctacatca gaaaaacgta cgcgattagc ttttttgtct gcttctttgg cttttgattt
     5341 accaaagttc atgacacggc cgccaccgcc accgccgccg ccttgttgtc ccatcatcat
     5401 gtaaaagaaa aagatgatga ttacgattgg caagaagcta agcaataggg aaacccatat
     5461 accgctgctt gattcttctt ttactgttgt agcaactttg ttttcttttg ccagttctgt
     5521 tacttggctc aatgttgtat catttggcaa aatgattgtt gtgaaatggg tagtagtcgt
     5581 atctgttgaa cctaagatag ctaacccacc gctgttagcg acggtctgct gttctttgta
     5641 ttcaccagtg atcttatata caccatttgc aggctgcact tcaaattctt tgatcttgcc
     5701 tgcttgtagt tgttctgtga attttgagta ctcgatatct gacgatcgct ggccgttatt
     5761 accaaaaatg aaataaacga ccattaccat cgctaagatt acgaggacat aatacaaggc
     5821 atttttcatc atgccgttgt tctttttgtt catagttgcc ctccctaagc gtcaatttaa
     5881 tttaacagtt ttttatcaat cctgaccatt ctattgtacc ataatttaat tgagatacag
     5941 cattaatttg attgataaac actaggtttc aatacaccga tgtacggaag gttacgatat
     6001 gcttctgcat aatccaagcc ataaccgacc acaaattcat ttggtacgtt gaagccaaca
     6061 taatctgctt cgatatttac tactcttcct tcaggtttgt caagtagtgt aacaattttg
     6121 actgattttg ctttgcggta tttgaaaaga tccactaaat aagcaagtgt tcttccgctg
     6181 tcaatgatat cttcaacgat caacagatcg cgaccttcta cattcgtatc taagtctttg
     6241 acgattttta cttcccctga cgagactgtt gcattcccgt agcttgaaac atccatgaaa
     6301 tccaattcca aatacgtatc gatagaacga acgatatctg ccatgaatgg taccgctcct
     6361 tttaagacac ctactactag gggattggtg ttttggtaaa tttctgttaa ctctttgcct
     6421 agttctttgc aacgaacttg tatctcttct tgtgagatca aaattctctc aatatccttt
     6481 tccaacatca ggttctcctt ccaattgctt ctttttgata tttgtaaaga agtatgtagt
     6541 gtattttatc agtttcttca cgaatactca aatatgaaaa ggcaaaaggt atcaagctat
     6601 atatatttct tttggcatct gtaatgatcc aagcatgctg cctttgtgaa ttaggtactt
     6661 tctgatcgat aaaatatcta gatacttttt ttgtgagatt ctctgttaat ttaatgcggt
     6721 ctcctgcttt tcttttttcg acatacagtt gcacatcagc aggaatccaa atgtcatgag
     6781 aaaatagaga ccatgaatct gttgctttga tgtcccctgc attttcaggt ttgaccagac
     6841 caatccattc tgtttcattc aaatatattc cttgttctgg aatcagcaac aagcgctggt
     6901 cttctgtctg gctagttgct tgtttttctt ttttagagag tacaacaaaa tgatactctc
     6961 ttttcagtat ccaattattg ccaatactga gttgccattg gctttttttc tgttgccact
     7021 ggtctaaaat cgactccatt tgttgttctt tcaaaataat tcctgttttt gagaatgctt
     7081 tgtcgaaaaa ggagtaaaaa aaatagtatc gttcagcatc tgtcatttct tcaatcattt
     7141 ctgcagaaaa tcgaaattgt tcctcccact gttcgacttc cttttcgatc aactgtccca
     7201 tatatttttg aatgacttgg tctgcccatt ggatctgttg cgaaaattgc tggaaatgtc
     7261 tcaacgcctg tgtattttct tgtttcaatt gaggaactac caaatgacga agccgatttc
     7321 tctggatatc taacaattgg tttgtctgat cctcaaagta aacaagctgc gattccgctg
     7381 cataagtata taggtcttct ttgctaaaac tcagcaacgg acgaatcagt ctgcccgtag
     7441 caaatggttg tacttctttg attccagaaa aagtatttaa ctgtccccca cgaacgattt
     7501 tcattaacac cgtctcgatt tgatcatctc cgtgatgagc agtcatcaac gtgtcatatt
     7561 gtccttcttc catcacgcga gtgaattctt gataacgaaa gttacgagct tctgtttcta
     7621 tggcggattt ggctggatct tcccaaatac ttacatataa agggagattc ttctcttcac
     7681 aatatgagcg aagataggca gcttcttctg ctgattcttc tcttaattgg tgattgatgt
     7741 ggacgatacc taaagaaaaa ccgatttggc gttgcacttg taaaagtaaa tggagcaaaa
     7801 ccatcgaatc aacaccacct gataccgctg ctaaaattct cgatccttgt tgccagaatc
     7861 cttgttcatt cccgtgccga ataaatgact gctgtaatag cggtgctttt ttcccgcctt
     7921 tttcaacgtt catcctttcc acaccctttc ttcctaaaaa aaagagagcg ggaaaacgtc
     7981 taaaacgaca attaacctgc cctctgttga tactatgacc caaatagtcg cactatcatt
     8041 atttgcggct ttttagctgc gacgtccgcc acggccaccg cgctttcctt ctgtgtttcg
     8101 cttcaatgaa gataagcggt catcgctatc tttcaaaaat gaactcatca atgaatcgaa
     8161 gtcttctttt tgagctgaag gttgactgcg agaaaaagat tttttctgtg ctggacgatt
     8221 tcggttgtca cggggatctt tttgttgata ttttttagga cggctttctt ctccagattc
     8281 agcaggttgt tcctgcgctt tccggataga tagtccgatt tttccatcat catttactga
     8341 aataacttta actgttactt catctcctac acttaaaaca tcatggatgt cttttacata
     8401 gccatttgac acttcgctaa tatgaactag acccgttttt ccagcaccta gatcaataaa
     8461 cgcaccaaaa tttgtgattc ctgatacttt tccttgcagt tttgctccta cctcgattga
     8521 cataaaaaaa atgttcctcc taattatttc ccttttttat attcctgctt attttgcagt
     8581 tgtagaacta gttgattgat ctgtttcatt tgtcgagctg tctgtatttg attctaatat
     8641 aggataaact ttttcaccgt cttttgagta aaagaatttg cttctggcaa gtttagctac
     8701 atactcatca tctttcagca atgaaacatc ttggtgcagc tgatcaacgt ctgcgttgac
     8761 ttctttcatt tcagtatttg cttcgactct caattcgttc aattgatgca tcctttgcat
     8821 gtcatggaaa atctgcacac ctattatcgc gaaaatgacc aaagcaccaa caaaaattgc
     8881 agccagtctg cgtcttcgaa aaatcagttg acgttgttgt tgctgaaatt cagcatactt
     8941 tttctttgca tattccgtat ctagcgcagc gattttattg ctttttttcg tcacttggat
     9001 tcgctccaat ctttttgatt gtctttttca ttataccaat atcgtgaaag cttgtctaat
     9061 ctatttctct agtgtttctg tgcgattttc agaaataatt tcgtacattt tttgtgcatc
     9121 ttcttttttg gttgattcat gtaattccgt aattttcact tccaacgttt tgttgccaaa
     9181 ctggactttc aaaatatcgc ctactttgac atcactggaa gatttcgcca atttaccgtt
     9241 gatttgaatt cttcctttat cagctacttc ttttgctact gatcgtcttt tgatgattcg
     9301 ggaaattttt aaaaatttat ctaatcgcat atcttattcc tcacttttta atttttttat
     9361 ttaatcgcag gattttctta ccaaaaggca acattagcca ttctcgtact gtaaacagac
     9421 gaagacgaat cactgcataa atgaacacag aagccccgat cccaactcct atcacgctga
     9481 caaaaaaagc agtggaacga tgagttacag gaccaaatac tatattcaat acaccataat
     9541 acagcagcag tactactgtc atacaaagaa ggctgaacat caacttccgt ccaaaatgcc
     9601 gttctttcca aaaagcattt agctcttttg tttcaattcg aacaaaatac caaagcgtca
     9661 cacctaatcc taaaagggta gacaggcttg cacctgctgt tcctaataaa ccggtcagaa
     9721 aagaagtagt caatcctttt accaatagtc cccatcctgc gccttttaaa gaagggcgaa
     9781 acgagttctt gctttgagca atactttgat aagcttggat gactgcagtg aaagcaatgg
     9841 aaaaaacaaa taatacaagc gctgcatttc ccgcataatc tttaaacaac gcataattga
     9901 tataagggag cagcaaggct aatcccaaag acgcagctaa tgctaaagcg gtcgtcaatc
     9961 taagatagat tttggctgtc tgtaaaaact gacgatagat ccggttggtc aaatgacgag
    10021 tcaacgcagg caggaatgtc gcacttaatg cagtggcaat cactaaacct aattgtacta
    10081 aaggctgacc tcgatcatag accccttttg ctatcttcgc accgtattct gacagtccgt
    10141 aaacttccaa agcatttttt acaaagaaag agtcgatcag ctggaaaaag ataagcaatc
    10201 cactataaat cgaaaccagt ccgccttcta ccagaaaacg ccggatcaag ggctttgacg
    10261 gctgtttgaa caatggaaac cgtcggaagc ttaacgctcc tccatgaatc ttttgttcat
    10321 agtagtgaag gatcccatat gcgcataaac cgccaaaaac agctccactc attgctgccg
    10381 tccctgtttg gtacaccgtc catccaagct ttctaaaagc aaacgcacta cagacaatca
    10441 caaaaacacg aacgaactgc tcaactactt gagaaacagc agttggttcc atcaagaatc
    10501 ttccttggaa attccctcga taaaaagata gaccaggcat cagcaaaaag gtaaaggaaa
    10561 ctacttggat cagcggtttc aattgtatgt ctcccatcat ccaagcaatc cagctgctaa
    10621 atgcaaagac aaacaaccac aaaaagacac ctgtccaaaa tactaaggga taaagatttt
    10681 gcaaagcttg ctttcgctcg aaaggattct ttctttctgc aacgtacttt gatatgaact
    10741 gcggaagacc ggataaagct aaagtcattg ctatcccata aattggataa acttgctgat
    10801 aaacataaaa accttcgtcg ccgactaagt tttggagggg aattcggtaa agggcactta
    10861 atacttttgc tatgaaagaa gcaatcgtca atacaaatgc tccttgcatg acgcgccgca
    10921 tttctttatg atccaaatca ttgctccttc ctacgctgac agatattttt gctcacgcaa
    10981 cgctttgaca aacttttgga tttcctgaag ccatactgct tcttccattt ggttggggat
    11041 cgtcaagcgt atcaccatct gttctttttc aacgcctaga ctggctttta gttttgtcgc
    11101 tgtcagtgct tcgaataact gttccacact atagcgtttt gttccaactt tacttagagt
    11161 aaagactata tgcgcctcct gtttccttat cgtttctagg agcgctcgat cgccatccat
    11221 tttgatctgc ccaattgtca agagatgtgc tacttcttct ggatattctc caaaacggtc
    11281 gagcagatca tcttctagtt catctagcat ttcttgcgaa tcaagttcac gaattcgttt
    11341 atagatctcg attttctgcc gttgatctgc cacgtatgtt tcaggtagat acgcatcgac
    11401 accgaggtcg atctcaacag tggtcttctc cacttgacta ttctttcctt gtttacgaga
    11461 aacagcttcg cttagcattt gagaatacat atcgaaaccg actgcatcaa taaatccatg
    11521 ctgctgagca cctaagagat tacctgcacc gcgaatggaa agatcccgca tcgcaatctt
    11581 gaatccagat cccagttctg taaaatcttt gattgcctga agacgttttt cactgacttc
    11641 gttaaggatc ttctgctgct catacataaa gtaagcatat gcgacacggc tgcttcttcc
    11701 tacccgccct cgcaattggt ataacgtgga taatcccata taatcagcgt tctcaacgaa
    11761 caacgtattt gcgttcggga tatctactcc tgtttcaatg atggttgtag tgacaagaac
    11821 atcatattga ccttcaataa attcaaaaag cgtattttct aattgcgcct ctgtcatttg
    11881 cccatgagca taaccgatcc gtgcttccgg aacgagttct tggatttctt ctactttttg
    11941 ttcgatcgtt tctacccgat tatataaata gaatacttgt ccacctcgtc ccatttctcg
    12001 atggattgct tcgcgaatag ccccaggatt tttttccata acatacgttt ggatcggata
    12061 acgattcgca ggcggtgttt cgattactga aagatcccgc acgcctaaca tcgacatatg
    12121 caaagttctc ggaatcggtg ttgcagtcag agtcaaaaca tccacttgtg cacgtaactg
    12181 tttcaatcgt tccttatgtt ttacaccaaa acgttgttct tcgtcaatga tcagtagacc
    12241 caaatcgcta aattcaatat cttttgacaa aattcggtgg gttcctacaa caatatcaac
    12301 ttgacctgta cgcagttgtt cgatggtttc tttttgttgc tttcttgttc tgaaacgact
    12361 taatagcccg atatttacgg ggaaaccttc aaatctttcc agcatcgttt catagtgctg
    12421 ctgtgccaag atcgttgttg gaactaaaaa ggctacttgt ttgctttcct ttatcgcttt
    12481 aaaggccgct cgaagcgcta cttctgtttt cccataacca acatcaccta cgagtagtcg
    12541 atccattggt ttttcttttt ccatatcccg tttgatctcc gctgcacttc tcaactggtc
    12601 atcagtttca gagtagggga aggcattttc gaattctttt tggtaggcgt catcaggtcc
    12661 aaaagcatat cctttttctg actctcttgc ggcatataat ttgattagat cgtcagcgat
    12721 atcctcgatt tttgaagaga cttttcgctt ggttttcgtc cattcacttc cgcctagctt
    12781 attgatgcga ggcgctttgg cttcagaggc gacatatttt tggatcagat tcagttgagt
    12841 aacaggaata aacagtttgt cgtcgttttg atacaaaata gtcatatagt cttggtgaac
    12901 gccatctact tctagcgttt ccatcccaat gtatttcccg ataccatgat tggcatggac
    12961 aacgtaatct cctgctttta actcattata gcttttcaat cgctctgcgt ttgttactgt
    13021 ttgacgtctc gtttgttttt tcgtcgtttt ttggaaaatt tctttttctg tgatagctac
    13081 tattttttct tgaggaagtt caaaaccagc ctgcaaagct ccttcaacta attgtacctg
    13141 tcctctgatc aatgcatttt tttctgtttc tactactaat atgtcttcat ctcgaagcat
    13201 ttgttctgct ttgcgtattc tgtcctttgt cggaataaag atcacaacag tctgtttttg
    13261 cttgcgccaa cggtccattt ctgttttcag caatggcatt tgtccgaaga actgttgcat
    13321 cgtccgatat tgaaaattat ggattgcttg gaaacgaaga tttcccatcc ctttttggaa
    13381 gagtgagaaa aaggttgtgg tgaacttttc cttctgcacg attttttgta tatctgctga
    13441 aaatgtctgc tcagaaaaca cccgcaattc gctgattttt tgagtctgcc attctgccgc
    13501 ttccctttcg atttcccgat ttgtttccat gattcgctga taatcatcaa cgactagtaa
    13561 actatttgaa gggaaataat ccaagatcgt cacagattct tggtaaagaa gatctgagta
    13621 gaattttgct tcttctgtcg ggacacctgc ttgccagctt gaagtcagct gaccgaagta
    13681 atcttgcaaa aactcgcggt ctgcttcttc tgtggtcgca gcaagccgtt tttctagcat
    13741 tttttgcatt tgctctattc catgttctag atcctctggt ccgtagactt gttcactcgt
    13801 tggggaaacc cagatttctt ccgttttttc gattgagcgt tgtgtttctg cttcaaaata
    13861 ccgcatagaa tctatctcta catcaaatag ttctacacga acaggatagg ttgtcgttaa
    13921 cgggtaaata tcgataatgc ttcctcgaat actgaattct cccggttttg cgaccatctc
    13981 ttctcgtaca tagcccatca aagtcaattg gcgaggaaga ttttccacgt ctatctcatc
    14041 accaatatgc caattcaatt gcgcctgtag ccaagttttc ttattcggca gtcgtttgtg
    14101 caaagatgcg actggcaaca aatagatacc tgcttttttt tcttgaagtg cgttaagcgt
    14161 tgcaactctc tcgcctcgcg cttctggaga agaaaaggcc atttcagcag aaagcacttc
    14221 atccactgga aataaatgga tctgatcttg cggaatcaca tgttgcagat cttctgctaa
    14281 ctgattcgca taatacaaat ttggcatcag aataatcatg tttttatttg ttttcttaaa
    14341 cgctcgagca aatagaagtg ttttcgctga gcccgctaat cctgtgatta gttgtctagg
    14401 cattttttct tctaaattgc tgacccattc ttttacttgc ggatcttttc cgactaattg
    14461 aataatatcc attccttttc ctccttcctc aattgaatcg attcatcgca tccacgaacg
    14521 aatgcccttc tatgagatat tcgactgctt taacagattg acacatgctt tcttctatca
    14581 aaggctgatt ttctttgctg aaaggactaa gcacatgctg gactactgtt tttttccctt
    14641 ctggcctgcc gattcccacc ttgattcgat caaagacatt cgtattcaaa tgggaaataa
    14701 tacttttgat accgttatgc ccgccggcac ttcccttttg acggagccgg atttttccca
    14761 ctgccagatc caaatcatcg tagattacga ctaattcctc tggataaatc ccaaaataag
    14821 tcattagtgg gccgactgca cgaccagatt cattcatgaa tgtttgtggt ttgactaaaa
    14881 ggatcttttc tccattatga aaaaattcgg caacttctgc ttcgaacgga ttttttttga
    14941 aagtagcttg atgctcgcgt gcaattttat ccacgaccat aaagccgata ttgtgttttg
    15001 tatattggta tttggtacct gggtttccta acccgacgat cattttcatt tttgttttcc
    15061 acctaattct aaaaagcagc acaaaaggct ggactgctaa ttagcggtcc agtccatcga
    15121 gcttttttct tttttatact tgtcaatgca tagtataaca caaaacaagg cgtttcggct
    15181 aaaagagaat cgttaataaa tgataaagaa attaaaaatt tcttcaaagt ttaatgaaat
    15241 aattgatata taaaaatagt gaaataacgc acatgtaagc ttttacatat aatacaacct
    15301 tgttatctgt tatattttat agccaaatag cgtgacatgg ggcttgagaa atgttagcat
    15361 aagcatggga aaaaacaaat caatggaagg attgatacta aatgactgca gctgcagaaa
    15421 aaaaagatca tcaaaaagtt attcttgttg gagacggcgc cgtaggttct agctatgcct
    15481 ttgctctagt tactcaaaat atcgctcaag aagtaggtat tgtggatatt aatactgcta
    15541 aaactgaagg agacgcaatt gacttgtctc acgctttggc atttacttca cctaaaaaaa
    15601 tctattctgc tacttacgca gacgcacatg atgctgactt agttgttatt acagctggcg
    15661 caccacaaaa accaggtgaa actcgtttag acttagtaaa caaaaaccta aaaatcaacc
    15721 gcgatgttgt cacacaaatc gttgaatcag gatttaacgg tatcttttta gttgccgcta
    15781 acccagtaga tattttgact tactcaactt ggaaattctc aggtttccct aaagaacgcg
    15841 taatcggttc aggtacctct cttgactcag ctcgtttccg tcaagcactt gcggaattag
    15901 ttgacgttga tgcacgtaac gtccatgctt acatcttagg tgaacacgga gattcagaat
    15961 tcccagtttg gtcacatgca aatgttgccg gcttgcaaat ctatgaatgg gtaaaaaaca
    16021 acccagaaat cgatgaagaa gctatggtta acctattctt tggcgtacgt gacgctgctt
    16081 acacaattat cgagaaaaaa ggcgctactt tctatggtat cgcagtagca ttagcacgta
    16141 tcactcgtgc catcttagat gatgaaaatg ctgttcttcc tttatcagta ttcatgaatg
    16201 gcgaatatgg attgaacgac atctacattg gtgcacctgc tgttatcaac cgtcaaggta
    16261 tccaaaaagt aatcgaaatt cctttaagtg acagcgagca agaccgtatg gctgcttctg
    16321 ctaagcaatt aaaagaaatt ctagatgaag cttttgctaa actagacgct gaataatctt
    16381 tgaacatgac ggaaaacatc tattcggtgt tttccgtttt tttattttat cacccttatg
    16441 gtttctaaat tttttcataa agtagagata accttcgtct tttcctctaa attatgctat
    16501 catgagaccg ttccacccta aacttttact taaggagttg tcgatatgac aagatcttcg
    16561 catcgaaaaa aatcgaaaca tgttgctttg ctttcagttc ttggtgttct cttagtgctg
    16621 atcagctttt atacctatcg cagtacatac tacacaaagc attttttgcc gaatacagaa
    16681 ataaatggaa taaatgtcag caatctaaca gtcgaaaaag caaatgaaaa attaaaagaa
    16741 gcttattctg ataaaaaact ggctattaaa gaagatggaa aagtctggca ggaagtacca
    16801 aaatccgagc tcggctacaa agatgatttc acttcggagc tttctccgat cctaaatgaa
    16861 caaaacggat ggacttgggg aatgacttat gtctcagcgg cagaaaaaca agaaatagat
    16921 cctgtcagtc aaaaccacca aaaactagac actaccgttc agacattgac aactaagctg
    16981 actgatttga acaaagaccg gacacctact actgatgcaa cgatcgaaaa agcaggtgac
    17041 tctttcgtta tcaagcctga agtcaatgga aatacgatcg acgtcgatgc tgcggtcaaa
    17101 caattaaaaa gtgcggtaaa ctctggtaaa gatacaattg aattgactga attcaaagaa
    17161 aaaccaaaag taacatctga agacagctca ctgaaagaac aactcgcatc catgaatgct
    17221 atcgcaaatg taaaagctac ttacagtata aacggtgaga ctttccagat cccatcaagt
    17281 gatattatga gttggctgac ctacaatgat ggaaaagtcg atttagatac agaacaagta
    17341 cgtcaatatg taacagattt aggcacaaag tataacacaa gtacgaatga cacaaaattt
    17401 aaaagtacaa aaagaggaga agttacggtc ccagttggca cttacagttg gacgatccaa
    17461 acagacagtg agacagaagc attgaaaaaa gcgattctgg caggccaaga ttttactcgt
    17521 tcacccattg tgcaaggtgg cacaaccgct gatcatccat tgatcgaaga tacgtatatc
    17581 gaagttgatc tggagaacca gcatatgtgg tattacaaag acggaaaagt ggcccttgaa
    17641 acagatatcg tttccggaaa gccaactaca cctacacctg ctggagtctt ctatgtttgg
    17701 aataaagaag aagatgcaac tttaaaagga acaaatgacg atggaacacc ttacgagagt
    17761 ccggtaaact actggatgcc gattgactgg acaggtgttg gtatccacga ttcagactgg
    17821 caacctgaat acggtggaga cttatggaaa acccgcggtt cacacggctg catcaacacc
    17881 ccaccaagtg taatgaagga attattcggg atggtcgaaa aaggaacgcc tgtattggtc
    17941 ttctaacaaa aataatatat aaaaagaaag cacccgtacg attggtacag gtgctttctt
    18001 tttattatct aacaatgtgc tacttacatt tcagcagcag taaagacttc tgaaacatca
    18061 tcatcgtctt ctagcttatc tactagacgt tccaattgct ctttttgttc ctcatttaaa
    18121 tcaatcgtcg tttgtggaat catcgtcaat tctgcttgcg ccaaagtgaa ctctttttcc
    18181 aactcatctc gtacagcagc aaaatcttct ggtgcagtat aaatctcgaa tacttcagga
    18241 gaagtttgca gatcttctgc ccccgcctct aatacatcct caaacatcgt ctcttcatca
    18301 acagtcaacc catcgcgttc aatagcgata tatcctttgc ggtcaaacaa gtaactgact
    18361 gaacccgttt ctcccagtga tccaccgttt cgagtaaaag ctactcggac atttgtcgct
    18421 gtccgattac ggttatctgt caatgcatgg actaagattc ctactccacc cggaccatat
    18481 ccttcatacg tgatttcatc gtaattcgtt tcatctacgg cactcgtagc ctttttaatc
    18541 gcccgttcca cattgtcgtt aggcatattt gcagcttttg ctttgtccac aacaagccgc
    18601 aaagctggat tcatagatgg atcaggaccg cctgctttag ctgccatata aatttcacga
    18661 gaaagtttct gaaagacttt ccctcgtttt gcatcttggg cattttttct tccttggata
    18721 ttatgccatt tactatgtcc tgacatgatt tttcctccct tgttcttttg agaatacact
    18781 tctattctag tactatttca caaaaaaaca aagccacagc caatctataa acgcttcttg
    18841 aatgccgcaa aaagcacaca taatatcaca gcagtcagag caccgatcga atccaacatg
    18901 acatcttgga acataggtgt tcgtccaccg gtcatcatct gatggaattc gtccaaacct
    18961 gcgtaccctg ttgctgaaag ccaagcaagg atcgctgtca gccaccaaat ttttagcttg
    19021 gggaaaacac ctaaaaacaa gctgcctccc aaaataaaat aggtaccgaa atgtgcgccc
    19081 ttccttaaaa agaactctaa aaatttggcg tagcccagat ggtcgatact caccatactt
    19141 ccaccataat taaaacgtat acccgctaat gtgtctttaa atggctgatt aggcagccag
    19201 ctttctaatc gcgaaacttg tgattgctgt ccgtaagttt gagaagaact gtaaaataag
    19261 attataacga ctatcagtgc gattactaaa taaatatttc cgtttttcat ttgttttttt
    19321 gaagaattca taagtcacct ctgtatttta tcttagactt tttttgaaga aacaacaatc
    19381 attttcatag agacttcttc cataaaaaag tgctatactt aattttgtat tacaatatga
    19441 agggagtttt ttcatgagtt attcattaaa ttggaatcta gattctattt tttccggagg
    19501 cagtcattct gatgctttga accaacggat gaagcaattg gaagaccaaa tgaacgagta
    19561 ttatcaccgc gtaacaaaat ggtcacctag ttctgacaat gcagagcagt taaacgctat
    19621 tcttcaattg caagaaacga ttacgaatgg ttttacccaa tgcagcagct atattactgc
    19681 attgctttct gccaatgtca atgattcaga tgcaaaggtc ttatcaggca agctttacgc
    19741 aatgctgcct cgtctgcaat cagccgaaac tgtattgtca aagaaatttg cagaaatatc
    19801 tgacaatgat tggaatcaga tgctttctca atcttcgttt gaaacaattg cttttcgttt
    19861 aaacgagatt cgtcgtgatg gctcacaatt attatcagaa gctgaagaaa acattataaa
    19921 tacgctttct ttagatggtc taaatgcttg gagcagtcat tatgatacga ttgtagccag
    19981 catttcgatt cccttcgaac aagatggaca agtagtcgaa ttatctgctg gacaagcctt
    20041 caataagatg atgggcgatc cagatccaaa agtcagagaa acacttttcg cagcatggga
    20101 agaagcctgg aaagaaaagg cacccctctt cacggatact ttgaatcatt tagatggttt
    20161 tagactttct gactatgaac ttcatggtgt cacagatttt ctacaaaaac cattagagta
    20221 caatcggttg aagaaagaaa cattgtctgt catgtgggat acaatccaga aaaacaaaca
    20281 accccttgtt aattacttga ctagaaaagc taatcttttc ggtaaagaaa aaatggaatg
    20341 gcaagatcaa gatgcaccta ttattttagg cgatttgaaa gaaaaaacct ttagttttga
    20401 cgaagcagca gcatttatta tcgaaaactt taacaaattc agtccaaaaa tggctaaatt
    20461 tgcccaatct gcttttgaaa agagctggat cgaagcagaa gatcgtcctg ggaaacgtcc
    20521 tggtggttat tgtactgagt taccagaaac aaaagaatca aggatcttta tgacctacag
    20581 taattctgtt aatgaggttg cgacacttgc tcatgaacta ggacatgctt tccatagcag
    20641 cacgatgtgg gatttacctt ctttaaatcg cgaatatgcc atgaatgtcg cagaaacagc
    20701 aagtacattc gcagaactga tcgtagccga tgctacatta aaagtcgcaa aaacaaaaga
    20761 agaaaaaatc aatttgctag atacaaaact gcaaaatgct ttagctatgt tcatgaatat
    20821 ccattcccga ttcatttttg aaaatcgatt ctatgaagca cggcaagaag gattagtctc
    20881 agaagataag atcacagaga tgatggttga ggcgcaaaaa gaaggctatc aaggagcttt
    20941 agctacttac catccatatt tctgggctgc aaaattgcat ttctttattg atgacgtacc
    21001 gttttataac ttcccataca catttggcta cctctttagt ttgggcatct atgcttacgc
    21061 caaccaaaag ggagcaaatt ttgaagaaga atatatccat ttactacgcg atactgcctc
    21121 aatgacgacg gaagatcttg cgaagaaaca tttgaatgtc gatcttaccc aaccagattt
    21181 ttggcaagca ggtatcgaca tggtgactga agatatccaa acgttcatgg aattgacaga
    21241 agaatttatc tgatttctat tttatcacaa taaaaaaaga gttagtccag aatgggctaa
    21301 ctctttttga ttaatcattc ttacatgctg acagcaaagt caggggcaaa ccattgaact
    21361 gaaccaactt ttacgctttc gcctggttga ggagcatgga tatattgtcc tccgcctaaa
    21421 gcaatcgcta cgtggtaagt tccgccttgt gacccccaga ataacaagtc tccagctttt
    21481 gcttgagaaa ctgaaatttt tgttccagct gattcttgag gaactgtcca accaccgatg
    21541 tcacgaccag ttacttgcat gtaaacatag cgtgtgaacc ctgagcagtc aaagccactt
    21601 ggatctttac cgccccaaac atatggagta ccaatatatt tgtaagcttc tgctacgatt
    21661 gctgcaccat tcacacttcc agaaggagct ggagcaggtg ttacaggttt tggttgttca
    21721 ggtgttggtg ttggcgttgg agccggagta ctacttcctg tgccgtttcc tgtatcaaca
    21781 ctttgatctg ttgatggtgt tgtaggcgca ggtgttgttg attcttctgt tgttgaagat
    21841 tcaggcactg ttgttgattc ttctgttgct gaagattcag gcactgttgt tgattcttct
    21901 gttgctgaag attcaggcgc tgttgttgat tcttctgttg ctgaagattc aggcgctgtt
    21961 gattcttctg ttgaagattc aggtgttgtt gattcttctg ttgctgaaga ttgtgtagct
    22021 gatgatgatt cttcagtcat tgaagattgt gtagctgatg attcttctgt tgctgagctt
    22081 tgtgcagtag atgaagcttg agtagcttgt gcttcagcct ctgcttgttc gcgtgcttct
    22141 ttttcagctt tttcttgtgc agcttgttga cgagcttgtt ctgctagacg ttgttgttca
    22201 cgaatacgag cttgctctgc ttcagcttct gctttttgac ggttcaagtc agctttcttg
    22261 tcttcagcag ttgcttgttc agcagctaat gaagttttca gtacgttcaa atcagcttgt
    22321 ttagataaaa gatcgccttt ttgagattcc aaagcagctt ggttttcagc taattctttt
    22381 agtttagcat cgttttcagc ttttttgtct tctacagctt ttttatcttg tttttgttgt
    22441 tccatcaagt cgttgtttgc ttttaccatc gttgtcattg cttgaacgcg tccaatagca
    22501 tctgctaatg aatcagcatt caatacagca tcgatgtagt ttgagcttgt gttgcttact
    22561 tgtgcttcgc gtgcttgttt ttggattgta tcttcacgtt tttcaatacg ttcttgtaaa
    22621 tctgcaatgt cttttactaa ttgtgcagat tcttgacgca atgtatcttg ttttgctaat
    22681 aggtcttgtg cttgtgtgtt gatttcagaa acttggcttt ctaaggcatc gatttgtgat
    22741 tgtgcatctg cttgttgatt tttcaagtct gcaatctttt gatcttgctg ttgtatctga
    22801 gaatcaaaat cgtccgccgc ggcagcgatc ggtgatgcta cggcagtcaa ggtcattgaa
    22861 cataccatta ctgctgatat taaactcttt ttcactcttc attcctccga ctggcttaat
    22921 ttaataaata tctaaatata tttaagtctt tcttaacgat ataaaaattg taccatagca
    22981 gtgtgtcaac gatataatag ttatgttaca aaaatgtttc aaaacaactt ttaaaaatga
    23041 caaaactgtt cgtttcagaa aatgatcatg aaaaagccgc gttaagtcta gcatttctta
    23101 agataacaac gattcttttt cgctttcgac ctaaaaataa aaaaagaaat tattcatcac
    23161 tgaataattt cttaaaggga aaaatgaata atacaaatat aatcatgttc aacagcagtg
    23221 taggtcctaa aaaccttgta ataaaatacg tgttatttac tactgctaat ttaaaaatca
    23281 actggaccac catcgtaaac aattcataac ccgtgacaaa gatgatcata ctgaaaaatt
    23341 cagtaaagat gttgacatgg ataacgtctt tcattacata catcaaccat acaattaaag
    23401 ggagagctac tgcatagata ccgataacgc caatatagta agcgtcatag atagccccga
    23461 gaacaatcgt ggtaatcagt aaataacgtt tttcaaacgc catactgcaa cataataatg
    23521 ccaatatcag aaagtgggca tttgacatat aggtgccttt cgaccactcc cctagcattc
    23581 ttgttaaatg accatctatc aacatcaaaa agaacaaaac gattggcaga tagtacttca
    23641 ttgtttcttt cttcaacatg gactaatcct ccgctagccg ttggacaatc gtcacaactg
    23701 acacgtcata catttctgca taaggtttca cataaacttc ccgatccagc ccataactat
    23761 ctggtttcgt tttaataacc gtaccgatcg gcaagttagc tggagaattc cctccaagac
    23821 cggatgtctg gacaacatcc ccttctttga tatccgtatc accagttaat tgggtcacca
    23881 ctaaggcatg gagcttttca tcatagtttt taagcaaacc aaacgcttcg ccattagccg
    23941 aagatacccg tactggaaaa tgattggagc tttcattaga ggatgacagt aattcgattt
    24001 tagacgaagc cgtattgacc tcgatcactc ggccaatcaa tcctttttgc gacatgactg
    24061 ccatatttgc ttcgataccg tctttagaac ccttgtctac gatcagcatg tcctgccaac
    24121 tgtcaggcga acgagtaatg acatttgccg ttactttttc gtaactagtc agcgtctgat
    24181 tcaactcaag ttcttttttc aacgcttcga tttctctctc gtaattcttg ttttgctgtg
    24241 aaacgtcatc atagctatcg attttttctt ttagccgctc attttcggca taagttgaaa
    24301 aaagattatg gacagaatct actccatttc gtacccaccg tactggggca gagattgttt
    24361 tatcaaccat tgcaacactg tcattaacga tggattggaa gaaattgggc tttccttcat
    24421 tcgctcgctg cgcagcggtc acacttagta tcgtcaccac gatgataaca ataaccaagg
    24481 taataataat atttttatta ggattgaact tcttcacaaa gacacctcga attaattaga
    24541 ctcttgtgtt caattttatc actaaatgcc gtgaaacaaa aggtaagttg ctcctcttaa
    24601 gctttttttt agcaaataat agattctgtc atttttagcc tgaaagacaa atttttttat
    24661 ttgtttatgg atcaatcttt gctttgaata actgcaatca taccatctga aaaagaaaat
    24721 tctgcggtat ctgaaagaaa ttcgttactt gcataagatg tcggatattc tacttcttta
    24781 ttttccaata catacttgct gccttttaat gtaagattcg agacgggagt caagcagcaa
    24841 taagctaaat acttcatatc tggtatctgt cttactatat gctctccagg caaataataa
    24901 gacaaataat tttgacaatc tctgataata agctgatggg caaagggttt gaagcgaggt
    24961 tccataccta accagagatt ggctaaaaga tgatccaatc ttccgcccgt agctccaatc
    25021 aaagtgactt ccgcttgcgg gtaacgttca aatgttttta agatacctaa ctgtgtatct
    25081 gtatcgtctt tttctgcagg ggaacgggta tactctttgg cttttgcaaa tacttccttc
    25141 tgctcttcgt tcgacaatga atcaaaatcg cccactgcca gatctactgg gtagcctgct
    25201 tgaagcaggt acagcgcacc acggtctatc ccgacatagg catcgtattt ggacagcaga
    25261 gactgcggcc agttttgcgg attacctcca gcagctaata aaattttcat ttagtctaat
    25321 gcctctttta atcgttcgat ttgtccgact ggattttcgg ctccatagat atatgatcct
    25381 gcaacgaaga catccgcccc tgcatcttta cagatttttg ctgtttctgg aacgattccg
    25441 ccatctactt cgattgcata agtccaattg ttctctctac gtagatcagc gagttccgta
    25501 attttttcta ctgtttcttc aataaagctt tgtccgccga acccaggatt gacagtcatg
    25561 actagtactt gatcagccaa aggcaaaaca tgtttgatca tggagactgg tgttcctgga
    25621 ttgataacta ctccagcttt aactcctaag ctttttgtca tttgaagtgc ccgatgaata
    25681 tgaggagttg cttcgacgtg gacagtaatg atatctgctc cagcttttgc aaatgctgga
    25741 atgtagtttt ctggatcaac gatcatcaga tggacgtcta acggtaattt agtaacagga
    25801 cggattgcct gaacaatatt tggccctaat gtgatatttg ggacaaattg gccatccatt
    25861 acatctacgt ggatgtaatc tgcgcctcct ttttccacta actcaatgtc tctttgtaaa
    25921 ttggcaaaat ctgcactcaa aatggatggt gctatcttca ttcttgtttc ctcctatttt
    25981 cgtttacctt ctttttttgc atacattggt tttctttttt cgatttcttg taagaattgc
    26041 aaataattgt cgtaacgtgt ctgtgcgata ccacctgttt ctactctatg ttttacttcg
    26101 cagccaggtt ctttagcatg catgcactct ctaaatttgc aatggacaga agcttctaca
    26161 aattcaggaa attgtctcgg cagttctcct gcttcaattg tcaaaaagtc aatcgagcta
    26221 aatcctggtg tatctgctac taacccgcca tagataggaa tcagttccac atgacgtgtt
    26281 gtatgccgtc ctcttccaag tgcatcagaa atctctcctg ttgctaaatt cagttccggt
    26341 gatatttgat tcagtagcgt cgattttcct gctccagact gacccataaa gaccgatagc
    26401 cgttctggga agtaacggat cagttctgtc gtatcacccg tatgattggg tacaatcacc
    26461 ggatagccta ttttagtata ggtttgcttg atctcttcga ttttttctgg gtcgtctgac
    26521 aagtcggtct ttgtcaaaaa aataatcggt tcgatcgact cgtattccaa ggtaactaga
    26581 aagcggtcaa gtagattata agaaaatgca ggctctacga tacttgtgac aatgattcca
    26641 agatcaacat ttgtgactgg tgggcgaact aattgatttt ttctcggcaa gatttccaga
    26701 agatagccgt ctgtttgatt ttcactctca aagatcacct gatctccgac aagcggcgtg
    26761 attttccgat tccggaaatt tcctcttcct cttgtttgat aggtctctcc gtttgcgtat
    26821 acatagtaaa aaccgctgat tgcttttctg atttgtcctt tgataagtgc cacctccgtt
    26881 tttgtttatt ttaccatacg aagaggaaag taggtgttat tccatgcaaa cttctcaaag
    26941 tatatggctt gaaaattgat caaaagagat agaaacacaa aaaagagaat gcaacaaatc
    27001 aatgtcgcat tcccttctga tatattttat tcagcactta ttttgaactt tctgaggtgc
    27061 tagctgatga acttgtggag ctggaagatt cttcttttga agagttgctt gtgctactgg
    27121 agctacttga gctgctagaa ctgtctgaag agtctttttc agaactagaa gacgctggat
    27181 ctggtccttt agagtaaatt acgttcacaa ccattccttt ggtaattgtc gttcctgccc
    27241 ctggtactgt acgaatcact ttatctttat ccaccgtgtt tgaatattcg gaagtctcat
    27301 gcccgatata ttctgcaccg acactagcta aataactttg tgcttcgctt tttgtatagc
    27361 cggagatatc attcaattta ggctctgttc cttggcttac gacaaaattg atgtaagttt
    27421 cttctgctac aacttcaccc gaggctggat cctgactgat gatcgaacct gatggtacag
    27481 tgtcgctata gtcataagta gcactaatat tattgatatt gaatccttgt gtaacaagcc
    27541 aattacgaac agtttcgtag ttttctccta catgactact caaagtcact gtttctggtc
    27601 ctttgctgac tgtgaaagta atcgtgtctg ttttaggatc gacttctgta tcttctgatg
    27661 gagattgcga aatgatcatt ccgctttcta cctctgaact gaattcctct tctttttgaa
    27721 tcaagtcagc agaaaaccct aattctttca aacttgcttc ggcatcttca taacttttac
    27781 cactgtaatc atctaatttg atttttttcg tgccgctact aatatacaga gtgacttcgc
    27841 gtttttgctt gactgtcgtt cccgctgccg ggtctgtctt cactacatta ccttcttcga
    27901 ttttgtcatc tgcaatttct tctgtttttg ttgctacttc taatttcgct tttgcgagtg
    27961 tttctctagc agaagcttca gaaagatcag aaacatcagg aacaacaact tctcctcgcc
    28021 cgccagaagc aaagaataca gctgttccga ttcctaaaac agcaagaata gctaatagga
    28081 tcagccacca ttttttctgt cctttctttt taggatcagg cagaacttct tcctcctctg
    28141 gcaaggtttc gttttctggc ttgtcttttg gcagaggcat agatttgaat gaatcaggca
    28201 ttggtgcatc ttccgtaagg ggtgtgataa cttttgtttc attatccatc acatgaggct
    28261 gccatttttc ttcgtttgca cgagctggtg ataatactgt agaaagatca tcagacattt
    28321 cctcggctga cttataacgg tctgcaggtt ctttagccgt tgcccgtaaa atcacgtttt
    28381 ccagtgcttg tggcacattt ggatcaagtg cttttataga tggaagatca tcttgaaaat
    28441 gttttaaagc aattgttaca gcagattcac catcaaacgg tacgctaccc gtcaacatct
    28501 cataaaggat gatccctaaa gcataaatat ctgactgctt cgttgccata cttcctctgg
    28561 cctgctcagg ggacagataa tgaacagatc ccagcatcgt attcgtctgc gtgatcgatg
    28621 tttcagataa agcgatagca atcccgaaat ccgtgatttt tacaacacct tcattatcga
    28681 tcagtacgtt ttggggtttc aaatctcggt ggatgatttg atggttatga gctaaagaaa
    28741 tagcagaaag gatctgctgc ataatattta ctgctgtttc ataaggaaca ggataatgtg
    28801 tttggatata tcgtttcaag tccattcctt tgacgtattc catcaccaga tactgcatgt
    28861 tgtcttcttc accaacatcg taaacactaa caatgtttgg atgaacgagt tctgttgctg
    28921 ctaaagcttc tctctgaaat cgtcgaatcg cagtctggtc attttgaaag tcaaatcgta
    28981 agactttaac tgctacatca cgatccaaga ttaaatcgtg cgccaaaaat acatttgcca
    29041 taccaccgct accgatattt ccagtgattt gataacggcc atttaatttt ttgcccaact
    29101 cgatcataca ctgtcctcct tatattcgat aagaagaacg gtgatattat ccgctccgcc
    29161 tgcttcattg gcacgatcaa tcagctcagt tactttatga gacaatgggc cttcttgatt
    29221 gatgatcgtt cctatttctt cttcagacag catgttcgtc aagccatctg aacataacag
    29281 cagtcgatct tttagttgcc aaagatgagt agaaacatct acttcgactg ttccaggcat
    29341 gccgacagaa cgtgttaaaa tatttttcct tggatggttc actgccattt cttcgctgat
    29401 ttctcctgat ttgactagtt cattgactaa agaatgatcc tccgtcaatt gcatgatttt
    29461 atcttcacga atcaaataag ctctgctatc cccaacattg gcaatcgtga accagtcatc
    29521 tgacagagcg gccgctacga ttgttgttcc cataccgtta tattccggct gttcttgtcc
    29581 acgctgataa atcagcatat tttcttcttg aatcgattga atgaaccatt gggcgatttt
    29641 ttcatcgtca acagcttctt gtttttccca agcttcgcct agattcgtta ccgccatctg
    29701 actggcaatg tctccggcac gatgaccacc catcccgtct gctaatacag caagcttgag
    29761 acctgaacgg ctggtaaata cactggcata gtcttgattt gtgttacgtc gtcttcctac
    29821 atctgattga tattcaatct gcattttttc acctcattac tttttgcgca aacaacaaat
    29881 gaaaaatcca tctgtgtaaa actgatgcgg atacaaagtc aacattttct cttcgattga
    29941 tgattgtagc ataggattgg tcaaaacatc aatcctctca aaatcagggt gtctttccaa
    30001 gaaagcagaa acaacgtctt ggttttcttc ttttaagatc gtacaagtgc tataagtcag
    30061 aataccggaa gactttaaag ttggtgcgca gctttctaaa atttccaatt ggatttttgg
    30121 taaattcgct aattcatccg gctgtttttt ataacgaata tctggttttc gccgaagcag
    30181 cccaagacct gaacaaggcg cgtctactaa aatccgatca aactgctctg cttcgaactg
    30241 tttactgact tctctagcat ccatcttttg agcgtagaca gcagaagaga cacctagacg
    30301 tgctgcatta tcttcaatga gtttgacttt gtgttcgtgt acatctaaag cgaccacttc
    30361 tccaccgcat gacggatcta aaaaagaagc aatatgcgtc gtcttacctc cgggtgctgc
    30421 acaggcatct aagacatgat gttcaggctc gatttgcata gacggcgcta caagcatcga
    30481 actttcatct tggatcgtca tgacgccatc gtggaacaat gagctagaag ctaaatgccc
    30541 ttttttcgct actataccgt atggactgac ttggcttttt tcagctgtga tctcttcttc
    30601 ttgcaaaaca gtgatggcct gatctctgga aagtcggcgt gtatctactc gggcactagc
    30661 atggctaggc tgatatagcg ataaaccgag cttttcagtt tcttcgtatc cgatttgatc
    30721 caccagtcgt ttcgtcatcc atagaggcag gctgattttg acagaaagtc tttcgatagg
    30781 atcagcaatg ccttgcagat ctggtgctcc ttgacgctga taattcctca agacaccatt
    30841 tacaaatttc cctgtcccag gatttccttt tacttttgcg atttcgaccg cctcgtttaa
    30901 aatagcatgt gcagggactt tatctaaaaa ttctaattgg tatacagaaa gataaagaag
    30961 cgtcttgacc cagtcatcca ctttttttgc tttagcgatc aatggtgcaa cgtaaaattc
    31021 caatagtcgc tgatggctaa tcgtaccata gatcaattct gtaaataaac ccacatcttt
    31081 ttgatttagc tcgctttgtt tgatcatctc attcaacaaa agattcgagt aggcgccacc
    31141 cttgttcact cgctctaatg tcagtaatgc catatatcgt actgattttt tcattttttt
    31201 agggattttt ttcattattt cacctgctga ccaatctgaa cttgctgacc gcttccgtta
    31261 aggaaatcat gtacggcctg ttttccttta ccagctggct gtaattcatt gatggctaag
    31321 acggtctgtt taccgcaagc aatccataga ttttttttgt ctttccggat gatcgtacca
    31381 ggtgctttgt ctgtagtttc tgccaatact tcaaccgata ataatttcca gcgtatgccc
    31441 tcataggtcg tgaatgcaat tggccaagga cgcattccgc gtacttggtt gtcaatttct
    31501 tctgcagttt tatgccaatc gattgcttct tgttcccgtg tgatgtttgg cgaaaaagtt
    31561 gcttctgact cgtcttgagg tactggtttt tgtccatcca aaatattggg caatgtttct
    31621 agcaatagct ttcttcctaa aaggctaagc ttttcaaaca tcgtccctac atcatcttgt
    31681 ttagtgattg gtatgctttc ttgcgcatag attccgcctg catccatttt tttgatcatt
    31741 tccatgatcg ttacaccagt ttctttctcc ccattcatga tggcataatg aacaggcgca
    31801 cctccccgat atttaggaag taaagaagca tggacattga ttgcccctaa ttttggtact
    31861 tgcaataact tttcaggcaa gaattggcca aatgccgcag tgacgatcac atcaggcacc
    31921 aattcaatga tttcttccat ttctggcgaa ccggagattt tctctggctg cagcacacgg
    31981 ataccgtgct tcagagccgc ttcttttacc ggtgtcggcg taattactcg tttccgccca
    32041 actggacggt cgggctgtgt taccactgcc tggatctcgt aacctgattc tatcagccct
    32101 tcaagaatcg gcacagaaaa agcaggtgtg cccataaata ctagcttagt catcaagatg
    32161 ttcctccata tattcttcaa gttcttcttc cgggatctgc tgtatcattt tctcaatgaa
    32221 caagataccg tctaagtgat cgatttcatg ctggaaggca cgggctaaat agccaaaagc
    32281 cgtcacttct atctcttctc cgtctcgatc ataataacgc acggtcactt catctgctcg
    32341 cttgaccgtt ccatagacat gcggaatact gagacaacct tctacgtcaa ggctttcacc
    32401 ttttgcttcg atgatttctg ggttaatcag ttcaaatttc tcgccttcat ctacttcgat
    32461 cacagcaatt ctcttgtttt gtcctacttg aggagcagcg atccctattc cgtcattcgc
    32521 aatcattgtc tcatataaat tgtctaataa agcgattgtc tcgtccgtga ttacatcgat
    32581 tggctgagca gttcttttta atttatcatt agggtggatc aatataggat agcgcataat
    32641 ttggcccttt cttaaataaa gtttaatggt tcgttgtcaa ttgccacaaa aagaccttgt
    32701 cgctgttctt tctggcttcc attcaaaatt tcatccaaaa catgaggaag attcggttca
    32761 tgtttatatt tgatgattag ttgataataa tatcggtttt tcactctcaa aatcatgctg
    32821 ggcgttggcc ctaatagcaa gctttgaggg cttaacactt cttttagctg attggcaatc
    32881 tgaaagattt tctttgccgc tacttgttct tcaggatggc tggcggttat tttcacagta
    32941 aagtaataag gaggatagcc tccacgatgc cgtacatgca tttcctgctg ataaaactgc
    33001 tcataatttt gttttttagc taattctatg gcgtaatgtt gaggattgaa tgtttggatc
    33061 acgacttcgc ctgctttttc cgctcgccct gctcgtcctg aaacttgggt aagcaattgg
    33121 aatgtatgct cactagaacg aaaatccggt aaattcaggg aggtatcagc attcaacacc
    33181 ccaactaatg tcacttctgg aaagtccaaa cctttagcaa tcatttgtgt ccctaataat
    33241 atatctgctt cttttgcacc gaatttttgt aaaatctgtt cgtgtgcccc ttttcttcga
    33301 gtggtatcta catccatacg caaaatccta gcttgcggat aaagttctcg gagttcctct
    33361 tctacttttt gagtacctgt tccatagtag cggattttat tgccgccaca attaggacag
    33421 cgattgggaa taggttcttc atgtccgcaa taatggcagc gcattgaacg tgtatccata
    33481 tgcagtgtaa gagagatatc gcaattagga catggaagaa caaatccaca gtccctacac
    33541 atcacaaaag acgaatatcc tcgacgattg agcagtagga cagtttgttc ttttttgtct
    33601 aatcgatttt gtattttttc ctgcaaatta gcagaaaaag tagaggtccg atgattctga
    33661 aactcttcac gcatatctac gatctcaata gctggaagct gtgcagctgc tttggctcgg
    33721 tggtttaact gcaataactg ataaacgcct ttttgagctc gtgctcttga ttctaaagag
    33781 ggcgtcgcgc ttcctagaac tattgggcaa tgatgatatt tactgcgcca aattgctaga
    33841 tctctcgcat gataacgcgg tgtctcatct tgtttgtaac ttgattcatg ttcttcatcg
    33901 ataatgatca gcccgatatt tttcagcggg gcaaaaatag cagatcgtgc gcctactact
    33961 acttgcgctt cttcccgctc aatcttgcgc cattcatcat atttttcacc ttgggaaagt
    34021 ccgctatgta agaccgcaac tgattctccg aagcgtcctt tgaatcgctc gaccatttgc
    34081 ggagtcaatg cgatttcagg cactaacata atagccgttt tattttctga caaaacatca
    34141 gcgattgcct gaagatatac ttctgttttc ccgctgccag tgattccctc cagcaaaaag
    34201 acctgatctt tttgctgctg acctgctgtg atgatttgtt cgacagcatt tttttgttct
    34261 gcattcagtt ccaatgccgt cgtttggtca aatactcggt ctttataagg gtcgcgataa
    34321 cgttctgatt ctataaactc cagccagccc ttttcttttc cttgattcaa gacagcagta
    34381 ctgattcctt tatttttgaa ataagcaatt ggttcttctt ggctcagttc agataaacac
    34441 aaaagaagtt ctttttgttt cttggcattt tgccgtaatt ttgcccattc ttcttcgatt
    34501 tgcttttcag ttaacaaaga acggaccaaa cgaatcgttt ttactttatt tcgtgtatgg
    34561 acttcatatt tgatatctac taattgctct tggcgccagc gaatcaattg agaaaggctg
    34621 ccttcttctt ctgcttcctt ccaggaaatc acttctcgct gatcaaacaa tacctgaact
    34681 tctggtgtgt ctgccaaagg atagatcaat ttatcatatt ctgctttcat cacactcgga
    34741 agcatcgttt gtagacaagt gattttgaat gcgtaagtaa tttttttcat ataatcagct
    34801 aatgaaagta attcttcatt gaccaccgga gcaaggtcta gcaaacgaat aactgccttc
    34861 aaagatggat tagctgattc ttctgatttt tggatagcca taacaaatcc ttggacatga
    34921 cgattgccat taccaaaagg gacttctact cgcatcccga cttgcaaagc tgtttccatt
    34981 tcagagggaa ccaaataagt gaatggctga tcggtctgca tagtaggtac gtccacaatg
    35041 acttcagctg ttaatgtcat ggttcgtttc ctcctttttt tgtcttttct tatcaagcga
    35101 caaaaagttc cttgcctatt ttactagaga tcgatggatt tgtcttatct tctgccaaat
    35161 cctaacaaaa aattaacagc agataagaaa aaaaagaact gtgtcaaaaa gttcagacac
    35221 agccttttct accagacaat aagtggcgaa tgtttgaaaa ggaaacagct gggtttgctt
    35281 ttctttttag atgttcgctc tatttttctt tattacattt tttgctcttc acggatacgt
    35341 gattccaatt cgtgttgttc acgctctttt tgtgcttgac gttcctcttc ttccatcttc
    35401 aaacgttcac gttttaattc aggatgtgga tcattgacta catttcctgc atcgatttct
    35461 tctaaagctt gaccgacgct ttttactgaa tcaaaagaat ctagagtagg ctgtgcactt
    35521 gcatccaatt catgcgcgcg tttacttgct aaaatcacta gagaatattt tgaatttaca
    35581 cgatctaata gtgagtcaat tgaaggtttt aacatcataa gactacatct cctttaacat
    35641 tttaatatat ttaccgatta cgcgatctac tcgaaaatgt tcactggcaa taatgttttt
    35701 gattcgttca actgctagcg gcacttcatc atttacaaca gcatagtcgt aaagagccat
    35761 catttcgatt tcttcttttg caactttcat tcgttcttcg attacttcat ctgcatctgt
    35821 tcctcggcct acgatccgtg attttaattc cgctaaatct ggcggagtca aaaagatgaa
    35881 tacaccatcg ggcacttttt ctttgacttg ttttgctcct tggacttcaa tctccaagaa
    35941 aacatctttt ccttcatcca atgtcttgtt gatatatgac aaaggagttc cataataatt
    36001 cccgacatat tctgcgtatt ccagcatctc tccagcttcg atcattgatt caaactcttc
    36061 tttgcttcgg aagaaataat caacgccttc gacctcccct tcacgcattt tacgggtagt
    36121 cattgagatc gaatactgaa aatcattatc ctcactctca aaaattgctt ttcgtactgt
    36181 gccttttcct acaccggatg gaccagacaa cacgattaat aatccacgct ctgacatgac
    36241 gacgtccttt caactagtct ttttgtactt atcgtttatt ttgcactttt tttctgcaac
    36301 tttcaaggtt atctttaatt atagctagaa attggtaaaa aagctaccct gtaccaagag
    36361 gtcgtaaaaa agctgtcctg catcaagtaa taagaacagc caaacataaa cagcttctca
    36421 tgtttttcgt ttggttgggg ttattatcgc agatgcaagc ttttgaacgc cgtgtataag
    36481 aggtcgtgaa gaagccgatt agtttcgagt atgaagaaaa attttgtgaa aatagtttct
    36541 cacatttttg cataaatttg gcttaatac
//
LOCUS       DAZKKZ010000026        36499 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.026, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000026 DAZKKZ010000000
VERSION     DAZKKZ010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 36499)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36499)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36499
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.026"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            303..623
                     /locus_tag="ACG8LA_001354"
     CDS             303..623
                     /locus_tag="ACG8LA_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HFQ0203660.1"
                     /translation="MAWMELIIAGILEVFWSTMMKWSDGFSKINYSFYTVIGMIASFY
                     FLSKAIKSLPMSLSYPIWTGIGAVGSVIIGVVLFHDKLNLSTWFFVGMLLISIIGIKI
                     TSGH"
     gene            777..1682
                     /locus_tag="ACG8LA_001355"
     CDS             777..1682
                     /locus_tag="ACG8LA_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0203661.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSDGTICIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIDTIVNQLKMEKYIHKKAKSYSLGMKQKLGIALALLNHPSIVILDEPMNGLD
                     PQATRDVRKIITDLATQGTSFLISSHLLSELEKMVDELILINQGKIIKQCTMAELNQT
                     AQDFIVISTTNDLAARTILTEAGYTLEDPDKIKLLKENEELLGTVIQLLSAQNIHVTD
                     VQHLTNDLESSLLEILDSVKGEEEK"
     gene            1679..2452
                     /locus_tag="ACG8LA_001356"
     CDS             1679..2452
                     /locus_tag="ACG8LA_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HFQ0203662.1"
                     /translation="MTLLVKQELFKLIKKKSTAVLSVLLVVLLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMEAQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSVYLYLLAIIVTVLMKLILFPSISFTEKVSTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIVLFLALGYLVFKRKNV"
     gene            complement(2633..4057)
                     /locus_tag="ACG8LA_001357"
     CDS             complement(2633..4057)
                     /locus_tag="ACG8LA_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="basic amino acid/polyamine antiporter"
                     /protein_id="HFQ0203663.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNLASIVMSTVFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFIDNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGLLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            4268..4714
                     /gene="nrdI"
                     /locus_tag="ACG8LA_001358"
     CDS             4268..4714
                     /gene="nrdI"
                     /locus_tag="ACG8LA_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HFQ0203664.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEHEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQTFGFPFLADYELRGTPSDVTRIYQILAENNK"
     gene            complement(4779..6761)
                     /locus_tag="ACG8LA_001359"
     CDS             complement(4779..6761)
                     /locus_tag="ACG8LA_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose PTS transporter subunit IIA"
                     /protein_id="HFQ0203665.1"
                     /translation="MAKNELTLEELAKQIYKGAGGMGNVESIVHCMTRVRMKIINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQQMVDLAGVKLGEKLSSVSTATAN
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAATWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALAAGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKVVPQTSA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVVSSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAAGK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(6775..7671)
                     /gene="murQ"
                     /locus_tag="ACG8LA_001360"
     CDS             complement(6775..7671)
                     /gene="murQ"
                     /locus_tag="ACG8LA_001360"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016835 - carbon-oxygen lyase activity
                     [Evidence IEA];
                     GO_process: GO:0009254 - peptidoglycan turnover [Evidence
                     IEA];
                     GO_process: GO:0046348 - amino sugar catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HFQ0203666.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            complement(7674..8735)
                     /locus_tag="ACG8LA_001361"
     CDS             complement(7674..8735)
                     /locus_tag="ACG8LA_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MupG family TIM beta-alpha barrel fold protein"
                     /protein_id="HFQ0203667.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            complement(8946..9473)
                     /locus_tag="ACG8LA_001362"
     CDS             complement(8946..9473)
                     /locus_tag="ACG8LA_001362"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HFQ0203668.1"
                     /translation="MLYVTRHGETTWNAQGLVCGRADVPLTEKGQMQAQKLAEKVVDL
                     PVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYDGLPSKDENFQKAR
                     LAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIRVINAYFHPMPNEG
                     FFTFMVDNTELVSYE"
     gene            complement(9540..11042)
                     /gene="eat(A)"
                     /locus_tag="ACG8LA_001363"
     CDS             complement(9540..11042)
                     /gene="eat(A)"
                     /locus_tag="ACG8LA_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection-like protein
                     Eat(A)"
                     /protein_id="HFQ0203669.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            complement(11300..12421)
                     /locus_tag="ACG8LA_001364"
     CDS             complement(11300..12421)
                     /locus_tag="ACG8LA_001364"
                     /EC_number="2.7.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008887 - glycerate kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HFQ0203670.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            12547..13488
                     /locus_tag="ACG8LA_001365"
     CDS             12547..13488
                     /locus_tag="ACG8LA_001365"
                     /EC_number="1.1.1.169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008677 - 2-dehydropantoate 2-reductase
                     activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0015940 - pantothenate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HFQ0203671.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            complement(13638..14534)
                     /locus_tag="ACG8LA_001366"
     CDS             complement(13638..14534)
                     /locus_tag="ACG8LA_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HFQ0203672.1"
                     /translation="MNKNDVLLVAKNKSLYFLPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFDMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMNFSSSEPKTDLFFGATNNGRKERAESYKQEFIKR
                     DVTTNYFILPHRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYHFYRPENIFLLRERDLDELPEFLHTPFKPILSELLEFYDAENWAKR
                     FITNDSTIYEQYEYDLSSVENK"
     gene            14803..16143
                     /locus_tag="ACG8LA_001367"
     CDS             14803..16143
                     /locus_tag="ACG8LA_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015171 - amino acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFQ0203673.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAFLIGGLILYIVMKGLGKIVLSGGDTHHGLSGLIRPYLGAHSADFTDWVYWSMWIIN
                     IIAEAVAAASFLQLWFPHIPAWVFVFMLAVLTTIINLYSVRLFAETEYWLAFAKISVI
                     ILLIIFATYLVGQQMLGTGVFPTLQQLTDHGGFTPHGMKGIISSLLVVIYSYGGSELI
                     AITVSEADDPKRAIPKAIKGVMGRIISFYIIPLFLLLILFPWNTLAGTNVSPFVMVFE
                     KMNIPFAADIVNFVIVLALFSSINSGVYASSRILFFRLKDRKGSSRKLAVLNKHQVPQ
                     RAVLFCTSVLYLGVALSYFVGDKLFGYLAGSLSYTVLLIWIIISAASFVLALRKGTLW
                     DKGISFFALAVLGLIFLGILFTNSIGVTVLTGLLYLFIYFSYQKKNDAFVLTNE"
     gene            16361..16804
                     /locus_tag="ACG8LA_001368"
     CDS             16361..16804
                     /locus_tag="ACG8LA_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF305 domain-containing protein"
                     /protein_id="HFQ0203674.1"
                     /translation="MKKYWKFLLMIGVSTVVMFGMMYLNVYALDHIFFSRTRVFMALM
                     MGAVMAVIMLLFMWKMYENKKINVMILAASLLVFAGSLFMVRSQTTVNDTAWMKAMIP
                     HHSIAILASKRADLKDPEVKKLAEEIIQAQEEEIDKMKKMIKEME"
     gene            complement(17308..18726)
                     /gene="nhaC"
                     /locus_tag="ACG8LA_001369"
     CDS             complement(17308..18726)
                     /gene="nhaC"
                     /locus_tag="ACG8LA_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA];
                     GO_function: GO:0015385 - sodium:proton antiporter
                     activity [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HFQ0203675.1"
                     /translation="MGKKGTPSFLEATLVLMVIVLGIAIGVVGLKVSPNITILAAIGM
                     VMLYAVIKRYPTDWLHEGIINGIKPGIIPIFIFILVGSLIAVWIQAGIIPTLMVIGFK
                     LISVQWFVPSVFVVCAIVGSAVGSAFTVMSTIGIAFFGIGTTLGLNPALVVGAIVSGA
                     VFGDKMSPLSESTNLAAAIVDADLFKHIKHMMWSTVPAFVVSFFLFMILGHTSKAASL
                     SSIREVTDVLEANFTISIWSLIPLFLMLLCAWKKVPAILTILLNIAVAVGMIFIQNPQ
                     TSLTKLAGVIESGFVSNTGNQQIDSLLSRGGIESMMPTVSLIILTLSLGGLLIEFGLI
                     STVMERVSRKMTNTPNLIFTTLMTSIGVNIFIGEQFLSVILPGNAFKETYEKAGFDPT
                     VLGRTLEDGGTVINYLVPWGIAGSFVASTFGIPTLTYLPFVFFSLLSPVFSMVSAFTG
                     WGISKKFVKPQEAVSKTAQLEQ"
     gene            complement(19129..20352)
                     /locus_tag="ACG8LA_001370"
     CDS             complement(19129..20352)
                     /locus_tag="ACG8LA_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HFQ0203676.1"
                     /translation="MTTTISTNQLKDLIQYRLPEYQALALDIHEHPEVSNYEFYSSAA
                     LIKQLEKERFWVEKEVAGHRTAFDARYISNKPGPTIAFLAEFDALPGIGHACGHNLFG
                     TYSVLAASIVKQFIDETGGEIRVYGTPGEEGGENGSAKGSFVREGFFEDVDVALCVHP
                     AFRYGKTTESLANDPVDIKFYGVASHAAAAPEKGVNALEALIQVFNGINALRLQLPKD
                     VNIHGIITDGGVAANVIPDYAAGRFYLRAGNRQTLDKVYEKVENIVRGAAISTGTTFE
                     FGLFQNAVDDVIVTPSFDDLFFQHAKEAGVPDEEIETEQRTSLGSSDVGNVSQVIPTI
                     QPTVAISETYIAGHTEEFKAAAKSDKGLASIAIAAELLANTALDLLKEPKLLERIKQE
                     HQEIVARKKQEGATF"
     gene            complement(20383..21222)
                     /locus_tag="ACG8LA_001371"
     CDS             complement(20383..21222)
                     /locus_tag="ACG8LA_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HFQ0203677.1"
                     /translation="MKKIIRFVVITFVAIIWLAGCSQGKADTTDKKETIVKLGIIGED
                     TDVWDNVKDRLKKENINLEYVKFTDYNQPNVALADGSIDLNSFQHQFFLDNYNKEHGT
                     DLVSIGNTVNAPLGIYSNTLKDVADIKDGAKVAIPNDVTNGGRALLLLQTAGLIKVDK
                     AKGQAPTVSDITENRKNLDISELDASQTARALSDVDISVINSGVAVDAGFNPASDAIF
                     LEPVDDHARPYVNIIVARKEDENNKTYQKIVDAYQTEDTVKVIEKTSKGSSVPAWETF
                     GRK"
     gene            complement(21239..21919)
                     /locus_tag="ACG8LA_001372"
     CDS             complement(21239..21919)
                     /locus_tag="ACG8LA_001372"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter permease"
                     /protein_id="HFQ0203678.1"
                     /translation="MTDFFKTYLPNVYLIPDEFVEATKQTLYMSFWTAFIGGMIGIIL
                     GVTLVVTRPNGLLANRLLFEILDKLINIIRSIPFIILLSLLALTTRFLVGTTIGAKAA
                     LVPLIFGVVPFFARQIENALLEVDPGVIEAAEAMGTSPIGIILRVYLLEGLPGIIRVS
                     ALTIINVIGLTTMAGAVGAGGLGNLAISRGYNRFQTDVTIVATLLILILVFLSQFISN
                     QLIKKITH"
     gene            complement(21921..22994)
                     /locus_tag="ACG8LA_001373"
     CDS             complement(21921..22994)
                     /locus_tag="ACG8LA_001373"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HFQ0203679.1"
                     /translation="MIELRDVSVCFKQKEKEIQAVDSVDLTIEKGDVYGIVGYSGAGK
                     STLVRVMNLLQKPTAGEVIVNQTNLSQLSPKELRKERKAIGMIFQHFNLMESRTIFDN
                     VDFSLKYSGKSKQERRQKVNELLELVGLEEKASAYPKQLSGGQKQRVAIARALANEPK
                     VLLCDEATSALDPKTTLQILALLKKLNRQLGLTIVLITHEMQVVKEICNKVAVMEDGR
                     IVEKGSSIQIFSNPEEELTKDFIRTATHLDQALETIIAHSAFADQIANKWLVELSYIG
                     NQTNEPLIAHLYSKYQVTANILYGNVELLQETPLGSLIVTLAGETKQRKKALDYLIKS
                     GVKINILQKNDLDSRIKVIEGGR"
     misc_binding    complement(23050..23288)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     misc_binding    complement(23331..23564)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(23641..24312)
                     /locus_tag="ACG8LA_001374"
     CDS             complement(23641..24312)
                     /locus_tag="ACG8LA_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFQ0203680.1"
                     /translation="MKGAIFDLDGLLVDTEKTYRDGWLWGFQQFDIHIPKEIVDAWGG
                     KNWKQSFDILVKAAGSPEKVQEVRAKREEYFYQQLTSGAIHLKPYAKEILADLKERHM
                     KLGIATTTVTKRATDILDHFKLADYLDTFTFGDEVSENKPSPIPYLTALERTGLEASS
                     AFAVEDSLVGATAASRAGLGVVLIPDSSFVRNYTVEEKEKLKLLAEGKDLRTVIEMLN
                     KKTEK"
     gene            complement(24399..27047)
                     /gene="mgtA"
                     /locus_tag="ACG8LA_001375"
     CDS             complement(24399..27047)
                     /gene="mgtA"
                     /locus_tag="ACG8LA_001375"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015444 - P-type magnesium transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015693 - magnesium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HFQ0203681.1"
                     /translation="MEKKKDTQKIYAAFAGKTKQELFELFHASANGLTEEQIERSREN
                     YGENAISYGKKTPFIVEILKAYITPFTLVLIALGIISFITEYVLAAPGDKDLFGVAII
                     FTMVIVSGTMTLIQSVRSNQAAEKLKSLVKVTAAVKRNGKYTEIPMEEIVCGDLVRLS
                     AGDMIPADMRLLSAKDLFISQAALTGESYPVEKHAKVCEDDQQSETSYENLVFMGSNV
                     ISGSAEGIIVSVGNETLFGHVAETLSEKPIQSSFELGIHKTSMLLIKFMSLMAPAVIV
                     INGLTKGDWLEAFLFGLSVAVGLTPEMLPMIVTTNLVKGASVMAKKGTVIKNLNAIQN
                     FGAIDVLCTDKTGTLTQDKIILEYHMDCEGNEDDRVLRHAYLNSYYQTGLKNLLDVAI
                     IDEATETLDTDKINYQKVDEIPFDFERRRMSVVVADPAGKTQMITKGAIEEMLNISKF
                     IDLGGTVTPLTKERKEAVLAKVQSLNEDGLRVIGVAQKTNPSVVGEFSVKDESDMVLI
                     GYLAFLDPPKETTKQALKALKEHGVAVKVLTGDNELVTRSVCRQVGLEINELVTGEKI
                     SEMSDHELAQVAEDHEVFVKLNPQQKARLTTALRKNGHTVGFLGDGINDAPAMKVADI
                     GISVDTAVDIAKESADVILLEKDLTILERGLLSGRETFGNIMKYIKATASSNFGNMFS
                     VLIASTFLPFLPMLPLQLLFLNLIYDVSCISLPWDRMDKEYLDEPKKWNASSIGEFMV
                     YFGPTSSIFDITTYLLMYFVICPAVVGGSFHTLDSSQRVIFIALFHAGWFVESLWTQT
                     LVLHALRTPKVPFIQSNATFAMFVITTLGIIVGSVLPFTSFGAELGLMPLPGNYWLWL
                     FATVIAYLALVTAVKKIYIRRFQELL"
     regulatory      complement(27389..27563)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00380"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="The M-box (ykoK) riboswitch appears to function as
                     a genetic 'off' switch that is important for maintaining
                     magnesium homeostasis in bacteria; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="magnesium"
                     /db_xref="RFAM:RF00380"
     gene            27736..28173
                     /gene="ndk"
                     /locus_tag="ACG8LA_001376"
     CDS             27736..28173
                     /gene="ndk"
                     /locus_tag="ACG8LA_001376"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004550 - nucleoside diphosphate kinase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HFQ0203682.1"
                     /translation="MERTLVIIKPDGVRRHLVGSIIQRFEAKGLAIAEMKFETMTPEL
                     AKEHYQHLTERSFFDELIDYMTSGPVVYLVLVGEEVIDIVRKMVGATKAADAVPGTIR
                     GDYALPGTENIIHASDSRDAAVKEIARFFPPFDINKPSEKAAK"
     gene            complement(28195..29061)
                     /locus_tag="ACG8LA_001377"
     CDS             complement(28195..29061)
                     /locus_tag="ACG8LA_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HFQ0203683.1"
                     /translation="MYDGELIKKLRVNKKLTQSQLAEGICFKTSLVGIETNSVKKMSF
                     VTLRSFLERMNMTLAEYEWMRNQLDEPIKLKKKRRMLDRVQEDSFDPYKEISNNRRHF
                     KKTEDLYYLVLNLHMVEKTEVSETEFEFLRYECRIIEEYLMQIPDYGQFELSILADFP
                     WIFSDRFIENNYLKIKKRMRRLAQLNNHEQYLFTFLMNLTSFYIENGRLKKARSVNED
                     MKRSLAHKERSTVIYETLMADYYQRLISAALGEEKTKDYQEFFTVLEYMLGKNQRRSL
                     EKKLLAIAEPSN"
     gene            complement(29221..31314)
                     /locus_tag="ACG8LA_001378"
     CDS             complement(29221..31314)
                     /locus_tag="ACG8LA_001378"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008484 - sulfuric ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HFQ0203684.1"
                     /translation="MTQLKKLCQNRLAIVLTAVFFFWLKTIIAYYADFSLGVEGTIQY
                     FILWINPIATTLLFFGLSLYIKKPKPALAILLIIDILNTLLLYLNIIFYREFTDFITV
                     KSVLGFSKVSQGLSGSSFSLMKPHDVIYWLDIAVFIGLLVWLKVKKIPIKSNPVGKPM
                     AIAVTCLSGLIFSGNLALSEANRPQLLQRTFDRSYIVKYLGIDAYTIYDGIKTGMTSS
                     VRAHASSNGIDEVLDYTKKHYAEPNPETFGIAKGKNVIVLHLESFQQFLINMKVDGQE
                     VTPFLNSIFQNQATISFDNFFHEVGQGKTSDAENMLETGTFGLPQGSLFTELGSDNVF
                     QAAPAILGQKQGYTSAVFHGNVASFWNRDHVYKNLGYDNFFDRSYFDESDETLGYGIL
                     DKDLFRESAQYLEHLQQPFYTKFLSVTNHTPYYTDDKNFDFPSLNTGNSTVDNYVRTA
                     HYLDQSLEQFFTYLKKSGIYQNSIFVIYGDHFGISNTDNKDLASALGKDPDTWDEFDN
                     AQMQRVPLMIHMPGYTKGTVNHEYGGEIDVLPTLLHLLGIDDKDYLHFGTDLLSSQHD
                     QVVAFRNGNFVTPKYTVLGGKAYNNQTGEIIDTKAAGIDEEISKDQEKVKTALSLSDK
                     LNQENLLRFYVPNGFETIDPKKYDYKNEAERNEAIEKQKGEHSTSVFSKNGNKTTTNL
                     YPVTRTDVEQQKNNQ"
     gene            complement(32063..32686)
                     /locus_tag="ACG8LA_001379"
     CDS             complement(32063..32686)
                     /locus_tag="ACG8LA_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0203685.1"
                     /translation="MRKKRPFLLFWLFGFFLLLILSAAFSGKMTADLAQKETEKIVAS
                     KESVDNFKKEFSTYWWAEYKITANYEKGELDIYLPKGKEENQFINIDDVLSAISLRQY
                     QFKDKHLTVLLLTHDGDKVARLKNGKVITAYSEKVDKKVVADRLAEWKKTNEQVKKTT
                     VSSQKNESTGTSPSDSGSGQTITGSEENQASIITNESSQGQYQSYGQ"
     gene            complement(32845..34242)
                     /locus_tag="ACG8LA_001380"
     CDS             complement(32845..34242)
                     /locus_tag="ACG8LA_001380"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFQ0203686.1"
                     /translation="MKKYQFPANFWWGSAASGPQTEGRISGDGKGENIFDYWYKKEPQ
                     KFFDQVGPEKTSQVYTKYQEDVQLMKQTGHNSFRTSIQWSRLIPDESGTINEEAVRFY
                     HRYFDELIENGIEPFVNLYHFDMPMYLQEKGGWLNRETVEAYEKYAKSCFELFGSKVK
                     KWFTHNEPIVPVEAGYLYRWHYPEESDMKKAIQVGYHEALASALAIKSYHEMEQGGVI
                     GIILNLTPSYPRDESNPEDVKAAQIADAFFNRSFLDPAVKGEFPSELIEIVKELDLMP
                     VIHAEDLTVIKENTVDLLGINYYQPRRVKAKETPIDTKNGPMPEDYFDNYEMPGRKMN
                     PYRGWEIYEQGIYDILINVRDHYGNIDCFISENGMGVENEARFIKEDGMIHDDYRIEF
                     VQSHLKYVHQAIQEGANCLGYHMWTCMDNWSWTNAYKNRYGFISVDLAQDGKRTIKKS
                     GHWFKDVSDKNGFEA"
     gene            complement(34274..35245)
                     /locus_tag="ACG8LA_001381"
     CDS             complement(34274..35245)
                     /locus_tag="ACG8LA_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFQ0203687.1"
                     /translation="MASIRDVAKMAGVSVGTVSRYLNGQQLKEKNMKKIAEAISALDY
                     KENIIAKGLKNNRSFSIGLLINGISSRFGSEVVSGIERVAEENGYSLLLSGFADQPEK
                     IEQKIEYLMKHVIDGLIVFLSEEEWSGFEMLTKMSIPVIALNCPEGPAGIDTILVNDR
                     ESVAKVIAHHGEQGHKKIGFIAATQTDYVARERLAGAKEAVQNDPSIQLEVFTGDYSR
                     KSGYYGAKALLEKGATAIFVSNYNMSIGAIECFNQEGVRIGKDIAFSHYDYLDKNDLS
                     ILPKITITPPTDKIGERAAEQLLKRIKKEEEENEKVIVMENIIHGIN"
     gene            35619..36044
                     /locus_tag="ACG8LA_001382"
     CDS             35619..36044
                     /locus_tag="ACG8LA_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0203688.1"
                     /translation="MKKLIVLFILSAGLLTLTGCDLFGGSDQSSDETTDSSVLKAEKA
                     DTTNSVYTLKVRKDMDLSAGQLTFTDKKMEWTRTYQTQGTDSSESSEEKTVLTDIKIT
                     TKDDEYIISGKENKKETTVIFTKIGNYRLKDEDGNIYSL"
BASE COUNT        10565 a         7604 c         6396 g        11934 t
ORIGIN      
        1 gataatatat agaaataagg tctagttact gtttttttta aatgattaat aaataacaac
       61 ttctttctat gaaattgcaa agcattcatc ttcttttccg ctaacgatat atccgtcagt
      121 gcttggtaca ctttactaaa aagtatgaga ttgccgatat ctggataggt gtgctatact
      181 acagaaaaag atatacaatc tgccaccggg taggataaag aggatgatca ttccattagg
      241 tctttgaagg gatgattttc ctctttttgt gtattttttt atagttaagg aggaatgtaa
      301 gtatggcatg gatggaatta atcatagcag gaattttgga agtattctgg tcaacgatga
      361 tgaaatggag tgatggtttt tctaaaatca attattcttt ttacacagtg attggcatga
      421 ttgctagttt ttactttttg tcaaaggcaa tcaaaagttt gccgatgagt ctctcttatc
      481 ctatctggac agggattggc gcagttggtt cggtcataat tggtgtggtc ttgtttcatg
      541 ataagctgaa tctttccact tggttctttg tggggatgct actcatcagt atcattggca
      601 tcaagattac tagcggccac tagacacttg gaataagtac tgatcagaaa aaataagcct
      661 ttttatttaa tattcaattt ttttatgaaa aaataagaaa taagtccaat gacctagcga
      721 cttctccact catcaggtgt atgcttgtac tatctataga aaaggagtga atatttttga
      781 aaagtctttc ggtccaagaa ttatccaaga actttggtca caaacaagcc ctcagcgatg
      841 tcagttttag cttatcccct ggcaaaatcg ttggattagt aggtcctaat ggcgctggaa
      901 aaacaacgat catgaaagct attttaggac tgatccatta ctcagatgga acaatctgta
      961 ttggtgaaaa tgagatttct ccctctagtc ataaagggtt ggaacaagta ggagcattga
     1021 tcgaataccc gggtatctat ccattcttaa caggctatga tcatctgaag ttattctctg
     1081 aaaccaacga tgtatctgct atcgacacta tcgtgaatca gctcaagatg gaaaagtaca
     1141 ttcacaaaaa agcgaaatcc tactcgttgg gaatgaaaca aaaattggga attgctcttg
     1201 ccttactgaa ccatccgtct atcgttattt tagatgagcc gatgaacggt ttggatccac
     1261 aagcaacaag agatgtgcga aaaatcatta ccgacttggc tactcagggc acctctttct
     1321 tgatctccag tcacttactc agcgagcttg aaaaaatggt cgatgagctg atcctgatca
     1381 atcaaggaaa gatcatcaaa caatgtacaa tggctgaatt gaaccaaaca gcgcaagatt
     1441 tcatcgttat ctctacaaca aatgatctag ctgctcgaac gatcttgaca gaagctggat
     1501 atactttgga agatcctgat aaaatcaagc ttttaaaaga aaacgaagaa ttattaggaa
     1561 ccgtgatcca gctattgtct gcacaaaata tccatgtgac agacgtccag catctgacga
     1621 atgatttgga atcttctcta ttggaaattc tggattcagt aaagggggaa gaagaaaaat
     1681 gacattgctt gtaaaacaag aattatttaa attgatcaag aaaaagtcaa ctgctgtttt
     1741 atctgttcta ttagttgttt tgctcatagg aacagcactt ctagccaaaa aatacacgac
     1801 gatcattgat ccagttgaaa tgactgctca gctttttagt gccacatctt ggattgtctt
     1861 tatcatgatt gcagctgcaa gcacgatcat ttcgatggaa gcacaatatg gtacattgaa
     1921 aaatctcctt tatcgaaagt attctcgagg agaaatatta gtaagcaaat ggatcacatt
     1981 agttatttat tctgtttatt tatacctttt agctattatt gtcactgtgt tgatgaaact
     2041 gattcttttc ccttcgattt ccttcacgga gaaggtttct actggtcaaa cactgatcca
     2101 aagcttgttc acttatactt tgggtagtta tatcggttta tggctgattt taagtttagt
     2161 gttgatgatt gcttgcttta tcaatagttc cggcgcatcc atctcagcag gaatcgtctt
     2221 ttattttgct tcgtcaatca tatctggtat ccttattgca ctcatccaaa aatgggagtg
     2281 gatcaaatgg aatccgatca gtatgttgaa tctgcaaaac caaattggaa acgaagagat
     2341 catgaagcaa ttgactcatc tttctactaa tcaaatgcta ttcggtaatt tagcttacat
     2401 cgttttgttc ttagcattag gatatctcgt atttaagcga aaaaatgtat gatgactcat
     2461 caaaaaagag gctgtgaaag agacgttcag ccttattgcc gattggctgt ctcttaaaca
     2521 ccgtttattc tgaaaaagga gctgtgacaa catttgtgtc acagctcctt tcctagtatg
     2581 tttttgaata aacgacaggc tcacaacctc tctttatact tcttttatac ttctatacgt
     2641 gaagcatccc agtggcaaat aaaaccattg caatcactcc gaccatcgtc acacctataa
     2701 gtaaaatctt atctaagtgg atatgttgta caggctcgtt ttgctcctta cgtgctttga
     2761 ggtaaaaata aatgcctggc aagaaaagaa caagaacaag cattacttca ttaaaggcta
     2821 cgactagcat agcccatact tgaaaggcac ttgctaaaag ccctactaaa aattggaccc
     2881 attctttccg ctgataagaa agtttcattt ggtacaatcc taagaaaagc cacgtgaaga
     2941 aaatagctgc tgtaccaagt gtgtaagcaa agttataagc actgtcagtg aataataatg
     3001 aaagtaaaaa gacattcgta cataacgtcg tcaatacgat agcataagtt ggtgccccat
     3061 ttttgttgag ttttccccat gctttaggca aaagtccgtc ttcagccatg tttcccattg
     3121 tttcaatcgg taagatcgtc catgagagcc aaacaccaac taaagaaatg atcaaaccgc
     3181 cgttgatcac gactgctccc catttaccaa ccatcatttc aaacacatag cccatagcag
     3241 gctgcgcctt gatcgtttgc agctgattca tcgtcattgt cccatatgga agcatggaaa
     3301 ccaagacgta aataataatc aagccgaata tccctagaat cgttgctttc ccaacatctg
     3361 attgtttttt tgctcgtgaa cctacgacag aggctccttc aataccaaca aatacccaaa
     3421 gcatcaccat gatgcaactc aatacttgac tggaaaacgg gatcggctgt ccattcgcat
     3481 tcaatataat gtcgctagaa aagttatcaa tgaattgttg gatcgaaaac gtgctgatag
     3541 ctactacaat aaataaaaat aatggcacta atttacagaa tgtgacgata gcattgacga
     3601 aactagcatt ttcgactccc cgattcacta gccatgcata tccccataaa aagactgtac
     3661 tcatcacgat cgatgccaga ttttgcccac cttcaaatac tgggaagaaa tatcctaatg
     3721 cgctcatcaa caatgttgca aaagctacgt tgcctaacca gcatgtgagc cagtaacccc
     3781 aaccgctgat aaaaccagcg aaacggccaa aaccttcttc tgcgtaacta aagatcccgc
     3841 cttttaaatc tggacgtttt ttattgatat tattgatcga caaggagagc atcaacattg
     3901 ctgttcctac gagtacccaa ctgaaaatag ctgggccgcc agccgatccg gagatgtccg
     3961 tcataatacc aaatacgcca cctccaatcg ctgaaccaat tactaaggca gcaagtggaa
     4021 ttaaaccaat tccttttttc tgttgctctg tatccatgta agcatcctcc aaaataaaac
     4081 cgcttttatc aaaaagtata acaaaccttt tttattttta cttaattaat aaaaacttta
     4141 atagaaatat aattctaccg gcttttttct cattatacaa gcaaagcgcc tagtcccttt
     4201 ccaaattaca ccaccaaaaa acttaaaaaa gatgctatac taaaaggaaa gaattggagg
     4261 atgatccatg aacattttat atatatcgat ttcaggaaat acgcgtgcct ttgccaaaca
     4321 tctagcagaa tatgctgaaa aaatgcatgc agaagatcct gtcaatcctg aagttacttt
     4381 aaaagaaatc catgaaaata gtgattttac gaaagaaaca gaaccatttt ttactttcgt
     4441 tcctacttat ttagacggcg gaaatggttt agataacggt gatacagaaa tcttgaccga
     4501 aacgatgcgt gaatatctgg aacatgaaga caatcataaa ctttgtcttg gtgtagtcgg
     4561 tagcggaaat aaaaacttca ataatcagta ttgtctaaca gccaaacaat atgcacaaac
     4621 atttggcttt cctttcttgg cagattatga attacgggga acaccatctg atgtgacacg
     4681 aatttatcag attttagcag aaaacaataa ataataaaaa agaagaagct gaaaaataga
     4741 tttcagtttc ttctttcgtt tctattgttt ctatcatatt aagctttgac atccatcaca
     4801 ggtgcttttg cttttgcttt acctgttttt tccaagacaa agttttttac acgatccata
     4861 ttggttacca agacgatcat ggatgtttct ttgcctgctg ctttgatcgc ttctaagtca
     4921 gcttctgcta caagcgtatc aggtgtcact tgctgccctt ctgttacttt cacatcaaat
     4981 ggcgtaccgc ctaagtcaac tgtgttgatt cccatatgaa gcaagatttc taaaccattt
     5041 ggcgttgtga tcccaatagc gtgtttcgtt gggaagacag agctgactac cccagtaact
     5101 ggagaataga tatgtccgtt ttctggttct acaaagtagc cttcacccat catcttttgt
     5161 gcaaaaactg gatcacttgc tttatctaaa gaaacaactg ttccgtcagc aactgatgag
     5221 aggatagtca cactttcagc tgaagtttga ggtactactt tttcaggcac ttcatttact
     5281 gtggctgttt cagtcgctaa ttcttctttt tctaaacggt ctttaggaat accgaagaag
     5341 aatgtagcaa cgaagccacc agcataagct gccaataatc caaggatgta gcctaaccat
     5401 ttaccgtcag agatcaatgg gatcaaagcg gctcctgaag gtccaatagc gatagccccg
     5461 acatttccga tcattccgat cactgccccg ccgatacctc caccgataca agcagtaata
     5521 aatgggcgtc ctagaggtaa tgttactccg taaatcaatg gttcgccgat tcctaggatc
     5581 ccgactggta aagctccttt gatcatttct gttaattctt tatctttttt gcagcgaatc
     5641 cataatgcca atgctgcacc cacttgtcct gcaccagcca tcgcaagaat tggaagcaat
     5701 agcgtacgac cagtttcatc aatcatttgc acatggattg gagtcaaaat ttgatgcagt
     5761 ccgaacataa ccatcggcaa gaataatgtg cctagaacga agccggcaaa tgctccacca
     5821 acgccaagta cccagttgat cccaccgacc atgccatcag aaatgaaacc tgctaaaggc
     5881 atgatgaaga aaatttcaat cagaccgatg gcaatcaatg aaagagttgg tgtaacgatg
     5941 atatctaccg catcaggtac tactttatgc agttttttct caacgattga caatagccaa
     6001 acagcgaaga tgacacctag gatcccacct tgtccagctg caagagcttc accagtaaat
     6061 aagtttttca gtggtgcttc cggattcatc cctgtcagca tcacaacggc cccgataact
     6121 ccaccaagag ttggtgttgc accaaaaact tgtgcagcat tgatacctgt atagataact
     6181 aggtagctaa acatcccgtt tttcaagatg ttcatcacat cgatatattg ttgccatgtt
     6241 gctgcatcaa gtgttccggc tgtgactaag tttgctaaaa ctgcggcaat ccctgccacg
     6301 atcccagtac cgacaaatgc aggaatcatt ggcacaaaga tattagaaat gtcttttaat
     6361 accgatttga ttttagatgg tttttgtttc gatttttgtg ccgctttcat ttcttgtgcc
     6421 cgttcgttta cacggtcttt tccagatgct gatgaatttg ctgtagctgt acttacagaa
     6481 gaaagttttt ctcctaattt cacgcctgcc aaatcaacca tttgctgtgc tactttgttc
     6541 actttcccag gtccgatgat gacttgaagc tgttcatctt ctactacacc aagcactcct
     6601 ggaatcgctt ttaattcaga gacatttaca agatcatcat tgatgatctt catacgcaca
     6661 cgagtcatgc agtggacaat gctttctaca ttgcccatgc cgcctgcccc tttataaatt
     6721 tgttttgcca gttcttccaa agtcagttcg ttttttgcca tggtcttttc cccctcataa
     6781 ggtccctttt acaaatccgt ttgcttcagc taattttgct tgagcttcct ctttatcact
     6841 atttgtcaaa atcatgacga tagccagctt aacattttga tctgcttctt caaagtactt
     6901 ttcagctgtt tcgtaatcag cttctgtcgc ttgcatgatg attcgttttg agcgttcgat
     6961 tagtttttca tttgttggtt tgacatcgac catcaagtta ttgaatactt tacctatacc
     7021 aatcatactg atagtagaaa tcatattcaa gataagtttt tgtgctgttc ctgacttcaa
     7081 tcgagtagag cctgtcaaaa attctggacc tgcatcgact tcgattggga aatccgcgtg
     7141 tttactgatt tcggcttgtt tattgcaaga aatcgttcct gtgacagcac cgatcgattt
     7201 tgcgtaatct aatccaccga tcacatatgg tgtacgaccg ctagctgcga taccaataac
     7261 tatatcattt tttgtcaaat tcagcttgat tagatcttct tgccctagct cataagaatc
     7321 ttcggcccct tcgacagcta cagtcattgc ttcttctcca ccagcaatta gacctatgac
     7381 catttccggt tctacaccga atgtcggtac gcattcagca gcatctaaca cacctagtct
     7441 tccacttgtt ccggctccca tataaatcag acgtccacct tttttaaagg actcaatcgt
     7501 gttagcaatc actggttcga tacttgtcag ttctttttca accgcagcgg ccactttctg
     7561 atcttctttg ttcattagtt gaacggcttg agaaatactc atctcatcta atccaaaagt
     7621 ttcttggttt ctgcgttccg ttgttaggtt ctctaaattg attttgctca tttttatctt
     7681 ccttcttttc ttataaattg atagttcata ccagctttga tttggttgat caatggtagc
     7741 tcttctttga taactttagc tactacattc actttttcat ccgctggcaa atcatatttg
     7801 gttaattgga tctcacccat atagcgcaaa tacttttcgt tatctaaagt aatagaccct
     7861 ttcatacgcg tagctgtatt tcttgctggg ataggcggaa tctctcgaaa acgtgcatct
     7921 acgcttcgta tgacatctct tgcatcgtct tgccgattcg tatgcttccc taatatatat
     7981 tcgtaaaatt cttcatctac aggttccgta tggagcaaga ctgtctgttc tttttggaaa
     8041 gaagcaaatt gctcctgaac gttttctgac agacctgcat ctccgatgta aacaatatcc
     8101 gtgttacttg ctaatagatc tagagcgcct gcaagaggat ggatccctcg atgttcttcc
     8161 aaagttggca atccttgata tagtgggcct ctcaactctg tatctcctgg tacaaaacct
     8221 tggacaagga gaccttgaat tttgagccat tgattttttt tctgatacca ttctttgtcc
     8281 agccctgttt cgggacgtgg ataataatta tgccaagctt caatctgtga gaaatcagct
     8341 tctgcttctt tcaattcatc gatatcttta ggcgtgatcg tgctagcatt caaactgatt
     8401 ttcaattgat gtgaccagtc ggcaatctgc tgattggaaa tatgataatc cattcttaaa
     8461 cctgttacac caattgcttt caaaggcgtt agatcttcta atgaaaaacc cgctcgttcc
     8521 aatgcctctc ctgaaatatc gaccatcaat tctagtttat tctttttcgc ttcgcttcct
     8581 agttcgatca atcgcttttg atatgccgaa acatcatctt ctggtatatg catggaagtg
     8641 aaaataccga caaagccatt ggatgccatt tggcggatat actgtttctt ctcttctgac
     8701 aaagaatcgt tcataaatat tgaaaagcca aacatattat ccctcttttt ctgtatccgt
     8761 cttcatttct atgactagag tatatatcta aagaaacaaa atttcaatac ttttattaaa
     8821 ataattaaat ttcatttcta aaggttgagt ttatattatc aaaagaattg tcataaccta
     8881 aaaaaggcac tgctaagcaa aagcagtgcc ttgaaatatt ttatttaaat aacacaaaaa
     8941 cataattact cataagaaac caattctgta ttatctacca tgaatgtaaa gaacccctca
     9001 ttaggcatcg gatgaaaata agcattgatc actcttatca aggcattatg gcaaactaac
     9061 agatagacat tttcttcgtc ttcgatgcat tctttcaata aaggaacgat ccgtgcatac
     9121 acatctaaga ctgactcccc atttgggaat cgtacagcga acgctaaacg tgctttttga
     9181 aagttctcat ctttgcttgg cagtccatca taatccccaa aatccatttc taccaatcgt
     9241 tcatcaacgg tcagcggcaa gctgagacga tcagcaactg cttgtgctgt atctcttgct
     9301 cgttgaagag gggaatggat gattttcgtg attggaacag gcaaatctac taccttttct
     9361 gctagtttct gtgcctgcat ctgtcctttt tcagtcagcg gcacatctgc ccgtccgcaa
     9421 actaatcctt gtgcgttcca agttgtttct ccgtgtctcg ttacataaag catgtgattc
     9481 tctccttcgt tggcaaagtt ccccttaacc ataccttgtt gttcttgaga ttacaagggt
     9541 tagattctct caagagaaat aatctcagta gatactttat ccaggaaggt ttgatcatgt
     9601 tccactagta acatggcagg tttcacgttc aagatcagtt gttctaattg ttcttgattg
     9661 aagacatcca aataattcaa tggttcatcc catgtatata gttcagctgg ctgtgataaa
     9721 gatttagcca attccacttt tttccgttgg cccatactca tctgctcgat cttgttatga
     9781 aaaacatctc tttccatccc aagctttcgg aggttgttca aaaatgcttg gtagtctact
     9841 tggtttttct ctgcaaattc cgccaacgtt cctcgattgt cttcataatt ttggcttgca
     9901 taactaatgc tcagatgttt tggctggtat ttttctccta taaccttgcc gttgaatgcc
     9961 cccagaagat aatggataat ggatgacttt cctgcaccgt taggacctga aatcgccacc
    10021 cgctgatgag gctcgattgt aaaatgaatt ggctcgaata acagattttc ataccctaat
    10081 tgaagatctt ctacgcttaa aagtcgctta tggtgagacg cttggctatt catcgtcaaa
    10141 gaatcgatat attcgatatc ttttaatagt ttttctttct cgctgatctg ggtctccatc
    10201 cgattcacga ttgctttgga tcgtttcatc gtccgtgcag catcagcacc cactgctcct
    10261 ttattcactc gtctagattc agtatcgatg aatccgactt gtttctttgt tttatctcct
    10321 tctcgggaac gagaccattc ggctttttca gctgctgttt tctttagcct actgacttct
    10381 tttttcaatt tttcattttg agccatttca aattcatcac gaagtttttt ctgttcttca
    10441 tagatagaga aattcccttg ataaagttcc agttgacttt tttcgattgc taaaacatgg
    10501 tccactactt catcgataaa tccccggtca tggctgacca cgatgaagcc ttgttttttc
    10561 tttttcaaat aagccgctac ttgttttcta ccagagatat ccaaatgatt cgttggttca
    10621 tcgattaacg ggaaatgagt gtcatccaca aataaaagtg ccagtaggac ttttgtcttc
    10681 tctccccccg atagtgtgct gaattctctc cataagattt caggatctgt ttgcatcaat
    10741 tggagctctc tttcgatttc ccatatctca aaatccgtaa tatcatttaa cacgtaatag
    10801 gttaaacgtt ctttatcttt tgtctgttgc gggaaatagg caaattcttg ctgatggatt
    10861 acttgccctt gataaggtag tttgttttgt agaatattca gtaaagttgt ctttcctcga
    10921 ccgtttcgtc cgataagtcc tagtttccat tgtgtgtcaa aatttagatt tgcttgttca
    10981 aataataatg tgccttggct gtcgtagccg aatgtcagat tttttatttc gattttagac
    11041 attttccatc acctcgtaaa aaaagaccag tcctattttc agaactggct aaagaggatg
    11101 caagggttgg atacacacaa aaagacccat acatcgaaaa aaccaagcca atcccgaaaa
    11161 tctgcacact gcttccttgt ctccacaagg tacagtctga atgcagcttt catcaatcga
    11221 cttaattttt caatgcacgg atccctcact ttgtcctata tttgaaatta cgatagcata
    11281 aagaaaatga ttttgtcaac tacttcggga ggatggtgaa aaatctgcta agtgtctgtc
    11341 ctaagatttt tgttttttct aatgtttgcc tgtgttccat tgcttcttct aaacctattg
    11401 gacccaaatg aatacttaag acaattggga gaaaatcaga aagtccttct agctcttggt
    11461 ctctacttcc gcaaatagcg attattggtt ttcgatattt ttttgcaagc actgctacac
    11521 cgtatggaac ttttccgtgg atcgtttgct gatcgatccg cccttctcct gtaatgatga
    11581 catctgcttg ttcgatcttt ttttccaatc cagtgatttg gctgactaaa tcgaaaccag
    11641 aaaccatctt cgctcccaac aaaaaaaggg ctccaccaat accgcctgct gctccacttc
    11701 ctggaatatc atctaaatcc acctcccaga aatcttttat ttgctgagca atctttcctg
    11761 cttgtttatc taagaaagct agcgtcgtat ctattcctcc tttttgtctt ccaaattgcc
    11821 aagcagctcc ttgttgacct gtatatggat tggtaacatc tgcagcgata atcaatttta
    11881 ctttagaaac aagaacgttt cttcgatcaa aatgaagttt tttagtagat aataaaggat
    11941 ttccttctgt gtacccttct aaagaagcac ccaaggattg gagtaatcct agaccaccat
    12001 cgctacaccc gcttcctcct aaagtgacaa taatttgttc tacttcttga agcagtgcat
    12061 ctttaataag ttctcctaag gcataactgg aagcaagtcg gatagtttga tccgttggtt
    12121 tatcaagtag atctaacccc aatgcttgtg cagattcgat gactgcggtg ttttttcctt
    12181 gccaagttgt caataaatag ctgatttttc gctgacggaa taagagatcc atcccatcaa
    12241 tggtacgcca tgttcccctg agcgcgtaat agattgcttc tgcagtattt tctccgccat
    12301 ctgcaatcgg cacattgatt tttcttcctt tacgatcttc ccagccattt agaactgcct
    12361 gatttagttc aaatgaagaa gcacttcctt taaatgaatc aattgccgcc aaaatatcca
    12421 tctgtatccc tcactttctt cttaagtaag acactttttt tcattttttt caaacaaaac
    12481 aatgctattt tcttccattt ttctatatac taaaagggaa ctcattgaat aaaggagaga
    12541 aaaaacatga aaatcgcaat agctggggcc ggagcaatgg gcagccgaat cggattgatg
    12601 ctacatcaaa gcggaaatga ggtcctcttg atcgatcgtt ggcctgctca cattgaagcc
    12661 attcgtacaa atgggttgat tgctgacttt aacggtaaag aagtggtcgc aaaactgcca
    12721 atctattcac cagaagaaat catcgaaagc aacgaacacg tggacttgat cgtagcatta
    12781 acaaaagcca atcaattaga tgatatgttt tgttcgatcc aatccattat tactgacaat
    12841 acttatgttt tgtgtttact aaatggatta ggtcatgaag atgtactgga aaaatatgtg
    12901 ccaaagaaaa atatcttatt tgggatcacg atgtggacag ctggtctagc tggtcccgga
    12961 aaagtcacat tgttaggtga tggagaaatc gaactagaga acttggaacc agaaggcgaa
    13021 gcatttacaa aaaaagttgt agaagtcttt caagaagcaa atttaaatcc gatctatagc
    13081 cataacgttc gttattccat ttggcgaaaa gcttgtgtaa atggaacatt gaatggttta
    13141 tgcacgattt tggattgtaa tattgctgaa ctaggcgcgc aaaaagcggc agagagcatg
    13201 gttcgaacaa tcgtatctga atttgcttct atcgcagcaa aagaaggaat catactagat
    13261 caagaagaag tgtaccaaca tattgcttct acttatgatc ctgacaacat cgggttgcat
    13321 tacccatcta tgtaccaaga cctgatcaaa aaccatcgtt tgactgaaat cgactacatc
    13381 aatggtgcca tttggcgaaa aggacaaaaa tatgatattg ctacaccata ttgtgccttt
    13441 ttgacccaat tagtccatgc aaaagaagga atccttggcg cagaataaaa ggctctctga
    13501 tgagaatcag ctgaatcagc agctggttct ctttttttaa gcccaataaa agatcaaaaa
    13561 gaaaacacaa ctctcatgat gccataagaa ttgtgcttgt ttgtttcagt acataatctc
    13621 ttcaaaatgt aggtttttta tttgttttca acagaggaga ggtcatattc gtattgctca
    13681 taaatagtgg aatcgttagt gataaatcgt tttgcccaat tttctgcatc ataaaattcc
    13741 aatagctctg ataggattgg cttaaatggt gtatgcagaa attccggtaa ttcatctaaa
    13801 tcacgttctc gaagcaaaaa aatattttca ggacgataaa aatgataatg agcaatcgct
    13861 tgattatccg tcactagttt cttttgaaaa tacatggatt caaatgtccg caaagtcact
    13921 ccttgctgac cctcccgcaa cagttccaga atcccgcgcg attcccctgt ttttttcagg
    13981 tactcttcat aagtaagata tccaggttgt tcattccctc gatgtggaag aatgaaatag
    14041 ttggtcgtaa catctctttt tataaattcc tgcttatagc tttctgctcg ttcttttctc
    14101 ccattattcg ttgcaccaaa aaatagatcc gtctttggtt cgctagaaga aaaattcata
    14161 tgtttcgaat aaaatgaact attatgtttc agcccaagtt cttttgcttc caaaaaatca
    14221 aaatgataaa tctcatcgat tgccggttca tcttgtgcct gcttcagcat cgcctcgtgt
    14281 tctgctttga agtgattcca aaaaaataac acaatttttg cattggtaaa tgggcgcacg
    14341 cgtcgagcca tctccatatc aaatccataa tctaaaaaaa cgatcagctg ataatttgcc
    14401 aactgttgtc tagctgattt aatgaattcc gactgtagta aatcttttcc ggaccaaaca
    14461 tctaaagagc ggatggaagg caaaaaataa agtgatttat tttttgcaac tagcagtacg
    14521 tcatttttgt tcatcttttc cgcctcactt tctctgtcac tttttcctat gatagcctgt
    14581 ttaaatagta aaaagccagt aaaacgtttc ctatatttgt atgaaaattt aacatttgta
    14641 tgaaaatatg atgaaataaa tcattcttct attaaaattc gcctaaaagt tttctgaata
    14701 gttgtaattg tctgaaaatt tgttatcatt agtcattgtt aaatattgct atttattctt
    14761 aatataaatt ttgattgtga atttaaaaga aagaggtcat ttatggaaga taaaaaattg
    14821 aaaaaacaac ttagctccag acatatcacc atgttagctt taggtggagc aatcggtgca
    14881 ggtctattta aaggaagtgg cgaagcgatt gggatcgccg gcccttctgt attgattgct
    14941 tttttgattg gtgggctgat tttatatatc gtgatgaaag gtctgggaaa aatcgtttta
    15001 agcggtggcg acacgcatca cggattatct ggtttgatac gcccttatct aggtgctcat
    15061 tctgctgatt ttactgattg ggtctactgg tctatgtgga ttatcaatat catcgctgaa
    15121 gctgttgcag ctgcttcctt tttgcagttg tggttcccgc acattccagc ctgggtattt
    15181 gtttttatgt tggctgtttt aactacgatc atcaatcttt attcggtacg gttattcgca
    15241 gaaacagaat attggctggc ttttgctaaa atcagtgtca ttatcttact gatcattttt
    15301 gctacttatc ttgtcggtca gcaaatgttg ggcacaggcg ttttccctac ccttcagcaa
    15361 ttgactgacc atggtgggtt tactcctcat ggtatgaagg gaatcatcag ttctttgctt
    15421 gtagttatct attcttacgg cggttctgaa ctgattgcta tcacggtaag cgaagcagat
    15481 gatcctaaac gtgcgattcc taaagcaatc aaaggtgtca tgggaagaat catttccttt
    15541 tacatcattc ctttgttttt gcttttgatt ctttttcctt ggaatacttt agcaggcacg
    15601 aatgtcagtc cttttgtgat ggtatttgaa aaaatgaata tcccatttgc agcggatatc
    15661 gtcaattttg tgattgtcct tgctttgttc tcatctatca attcgggtgt gtatgcatct
    15721 tcaagaattt tgttcttccg tttgaaggat cgaaaaggtt cctctagaaa actagctgtt
    15781 ttaaacaagc atcaagtacc gcaacgtgct gttttatttt gtaccagtgt tctttatctt
    15841 ggtgtagctc tttcttattt tgtcggtgac aaattatttg gctatctggc aggttccctt
    15901 tcgtatacag tattattgat ctggatcatt atcagtgcgg catcctttgt actggcacta
    15961 agaaaaggaa cattatggga taaaggaatc agcttttttg cattagctgt cttaggattg
    16021 attttccttg gtatcctgtt cacgaactcc attggggtaa ctgtattgac tggcctgctt
    16081 tacctgttca tttatttcag ttatcaaaaa aagaatgatg cgttcgtatt gacgaatgaa
    16141 tgaaatcgat agaaaatttt attttattta tgtggaatag atggagctat tgaagaaagg
    16201 agttgtgaca aaagtcttgt tgcaactcct ttttccgaat aaacagtctc atgacctctt
    16261 ggtaaacggt gttcaaaaac cctctgtgca aaataattga ttgttctcca tgctcatgac
    16321 atgatagaag aaaggaatga aaaaaaggag tttgttttaa atgaaaaagt attggaagtt
    16381 tttgttgatg atcggtgttt caacggtagt tatgtttggt atgatgtact tgaatgtcta
    16441 tgcgctcgat catatcttct tcagtcgtac acgagtattc atggcgttga tgatgggtgc
    16501 agtcatggca gtcatcatgc tgttgttcat gtggaaaatg tatgaaaaca aaaagataaa
    16561 tgttatgatc ttagccgcta gtcttcttgt ttttgccggt tccttgttta tggtacgaag
    16621 ccaaactact gtcaacgaca cagcttggat gaaggccatg attcctcatc attctatcgc
    16681 tatcctggca agtaaacgag ctgatttaaa agatcctgaa gtaaaaaaat tagcggaaga
    16741 aatcattcag gcacaagaag aagagatcga caaaatgaaa aaaatgatca aagaaatgga
    16801 atgaccatta tccgtccaaa taaaaaaaga ggatgttcca gaagttatca gcttcaagaa
    16861 ataagaagaa gctacttctg gaacgccgtg aataaggggt tgtgaaaaag ctgccctgca
    16921 tcaagtaata agaacagcca aacaaaaata gcttctccta tttttcgttt ggttaggctt
    16981 attaccgcag atgcaagctt ttgaacaccg tttattaaga ggttgtaaaa tcagcgttct
    17041 gacctgagta ttagagagac aaatggaaaa atagttcctc atattttgcc attttttgag
    17101 ctaataccga gggtcagctg attgaacacc gtttatcgag aggttgtgaa aaagtcgctt
    17161 agtttcgcgt attaagaaaa attttgtgaa atggctttcc acatttttgt ataaatttgg
    17221 cttaataccg agaaactggc ttttgaatac cgtttattcg taaaagggat tgtgacaaaa
    17281 gtcttgtcac aatccctttt tatgttttta ttgttctaat tgcgctgtct tgcttactgc
    17341 ttcttgcggt ttcacaaatt tttttgagat tccccaacct gtgaaggcac tgaccatcga
    17401 aaacacagga gaaagcaaac tgaaaaatac gaatggcaag taagtgagtg taggaatacc
    17461 aaatgtactt gctacgaaac ttccggcaat tccccaaggc actaagtagt tgattactgt
    17521 tccaccatct tctagcgttc tacctaatac agttggatca aatcctgctt tttcataagt
    17581 ttctttaaat gcattaccag gcagaataac agataggaat tgttcaccaa taaaaatatt
    17641 tactccgata cttgtcatca atgttgtaaa aatcaaattt ggtgtgttcg tcatctttct
    17701 tgatactcgt tccatcacgg ttgagatcaa gccaaattcg atcaacaatc cacctaatga
    17761 caaagttaga ataatcaatg acacagtagg catcatactt tcgattcctc cgcggctaag
    17821 cagtgaatcg atttgttggt ttccagtatt tgaaacaaac cctgattcga tgaccccagc
    17881 caacttcgtt aaggaagttt gtgggttttg aataaaaatc attcctactg ctacagcgat
    17941 attcaacaaa atcgttaaaa ttgccggcac ctttttccat gcacacagta acattaaaaa
    18001 taaaggaatc agtgaccaga ttgaaatagt aaagtttgct tctagaacat cagtcacttc
    18061 acgaatagat gaaagacttg cggctttact tgtgtgtcct aaaatcatga ataaaaagaa
    18121 agaaacaaca aatgccggga cagttgacca catcatatgc ttgatgtgtt tgaacaaatc
    18181 ggcatcaaca atagctgctg ctagatttgt tgattcggat aatggagaca tcttatctcc
    18241 aaaaacggca cctgaaacaa tagctccaac aaccagcgct ggatttaagc ctagtgttgt
    18301 cccaataccg aaaaatgcaa tcccaatcgt tgacataaca gtaaaggcac tccctacagc
    18361 gctacctacg attgcacaca caacaaatac agaagggaca aaccactgga cactgatcaa
    18421 tttgaaccca atgaccatta gagttggaat gatccctgct tgtatccata cagcaatcaa
    18481 tgaaccgact aaaataaaaa taaagattgg gatgattcct ggtttgatgc cattgatgat
    18541 tccttcgtgc agccaatctg tcgggtatct ttttatcact gcatacaaca tgaccattcc
    18601 gatcgctgct aagatcgtga tattaggtga gacctttaat ccgacaacgc caatcgcaat
    18661 gcctaaaaca ataaccatta atacaagtgt tgcttctaaa aaacttggtg ttcctttttt
    18721 tcccatgata atctctcctt ttttagttgt tcttatgttc taaaaaagtt aagatatcgg
    18781 attactccgc cgcaattcat ccgcgattcc tcctttataa aaataaaaag acctgtttta
    18841 aactaaggac gaatgactcc gcggtaccac cttaattaaa aacagatctg tttttcactt
    18901 tcaaactttt attcaaatgt atggactttc catgtaattc gtcaattagg cttgatcggt
    18961 tcacagcgac caccgacttt ctgaacaaaa cacctaaccg ctactgcgtg aaaagttgac
    19021 ttgtacgaag tttaccttcc ataagatcat ttgtcaatga aaaagaaaat attttttcat
    19081 ttttctgaaa attattttta taactttcac acacaagatt attttttact agaaagtagc
    19141 gccctcttgt ttttttcttg ctactatttc ttgatgttct tgcttgattc tttctaatag
    19201 ctttggctct ttcaacagat caagagctgt attggcgagt agttctgctg caatcgcaat
    19261 agaagcaagg cctttgtcac ttttagcagc agctttgaat tcttctgtgt gtccggcaat
    19321 atatgtctca gagattgcta ccgtaggctg gattgttggt atgacttggc tgacatttcc
    19381 tacatcagaa gaaccgagac ttgttctttg ttccgtttct atttcttcat ctggaacacc
    19441 tgcttctttt gcatgctgga agaataagtc atcaaaagaa ggagtaacga tgacatcatc
    19501 aactgcattt tggaacaatc caaactcaaa agtcgtgccc gtacttatcg cagcacctcg
    19561 tacgatattt tccacttttt catatacttt atctaatgtt tgccgatttc ctgcacgtaa
    19621 atagaaacgt ccagcagcgt aatctggaat gacgttggca gctactcctc cgtctgtaat
    19681 gatcccatgg atattgacat cttttggcaa ttgcaagcgt agagcgttga ttccattaaa
    19741 cacttggatc aatgcttcca aagcatttac tcctttttca ggtgctgctg ctgcatggga
    19801 agcgacaccg taaaatttga tgtcgactgg atcattcgct aaagattctg tcgttttccc
    19861 ataacgaaaa gctggatgga cgcataacgc tacatcgaca tcctcaaaaa aaccttctcg
    19921 aacaaagctg cctttagctg atccgttctc gcccccttct tcccctgggg tgccatatac
    19981 acggatttct ccaccagttt catcaatgaa ttgcttcact atgctggcgg ctaatacgga
    20041 gtaagtacca aacaaattat gcccgcatgc atgaccaata cctggtaaag catcgaattc
    20101 tgccaaaaag gcaattgtgg gaccgggttt attggaaata taacgtgcat caaaggctgt
    20161 tcggtgtcca gctacttctt tttctaccca aaacctttct ttttctaatt gtttaatcaa
    20221 cgctgctgag gaataaaact catagttact tacttcagga tgttcgtgga tatctagagc
    20281 aagtgcttga tattctggta aacgatattg gattagatcc ttcaattggt ttgttgagat
    20341 tgttgttgtc ataaaaaatt cctcctatgc tagtcatttt tcttattttc tcccgaatgt
    20401 ttcccatgca ggcacgcttg atccttttga tgttttctcg attactttga ctgtgtcttc
    20461 tgtttgataa gcgtctacta ttttttgata cgttttattg ttttcatctt cttttcttgc
    20521 aacgatgata ttcacataag gacgtgcatg gtcatccact ggttctaaga agatggcatc
    20581 agaagcagga ttaaatccag catctacagc tacaccgcta ttgatcactg aaatgtctac
    20641 atctgacaaa gcacgtgctg tttgggaagc atctaattca gaaatgtcta gattttttct
    20701 attctcggta atatcagaaa cagtgggcgc ttgtcctttt gccttatcca ctttgatcaa
    20761 tccagcagtt tgcaataaca gaagagctct gccgccattt gtaacatcat tagggattgc
    20821 tacttttgct ccgtctttga tatcagctac atccttcaaa gtgttagaat aaattcccag
    20881 cggtgcattg acagtatttc cgatcgatac taaatcagtt ccgtgttctt tattgtaatt
    20941 gtctaaaaag aattgatgtt ggaaagaatt caaatcaatc gatccatctg ctaaagccac
    21001 atttggttga ttgtaatctg taaatttcac gtattccaaa ttaatgttct cctttttcaa
    21061 acggtctttc acgttgtccc atacatctgt atcttctcca ataatcccta gttttacgat
    21121 agtttctttt ttgtcagttg tatctgcttt tccttggcta caccctgcca accaaataat
    21181 tgctacaaat gtaatgacta caaaacgaat aatttttttc attttttctc ctccactttc
    21241 aatgtgtaat ttttttaatc agttgattac tgataaattg acttaaaaaa actaagatta
    21301 gaatcaataa tgtagccaca atcgttacat ctgtttggaa tcgattatac cctctcgata
    21361 tagcaagatt ccctaatccg cctgcaccta ctgctccagc catggtagtc agtccgatca
    21421 cgttgatgat agtcaacgcc gagacccgaa tgataccagg caaaccttct aacaaataca
    21481 cacgtaaaat gataccgatt ggactggttc ccatcgcttc tgccgcttcg atcaccccag
    21541 gatcaacttc tagcagtgcg ttctcgattt gacgagcaaa aaacggaaca actccaaaaa
    21601 tcaatggcac taaagctgct ttcgcaccaa tcgtcgttcc aactaagaaa cgagtagtca
    21661 atgctaaaag agaaagcaag ataatgaaag ggatggaacg aatgatattg atcagcttat
    21721 caagtatttc aaatagcaga cggttagcta gtaatccatt agggcgtgtc actactaacg
    21781 tcacacctaa gatgattcca atcatcccgc caatgaatgc tgtccaaaaa gacatatata
    21841 gtgtttgctt cgtcgcttcg acaaattcat ccggaatcaa ataaacattg ggcaaatatg
    21901 ttttaaagaa atcagtcatt ttatcttcct ccttcgatca ctttgatacg actatctaaa
    21961 tcgttttttt gtaaaatatt tatttttaca ccagatttga tcaaataatc caatgctttt
    22021 ttccgctgtt tggtttctcc agctaaagta acgatcaaac tccctaacgg cgtttcttgt
    22081 aataactcta cattgccata taaaatattc gctgttactt gatatttgct gtacagatga
    22141 gcgattagag gttcgttcgt ctgatttcca atataactta attccaccag ccatttattg
    22201 gcgatctgat cggcaaaagc agaatgggca atgatcgttt ctaatgcttg gtcaagatga
    22261 gtagctgttc gaataaaatc tttggtcaat tcttcttcag gattgctgaa gatctggatg
    22321 ctgctacctt tttcaacgat tcttccatct tccataaccg ctaccttgtt gcagatttct
    22381 ttgacaactt gcatctcatg agtgatcagg acgattgtta aacctaactg gcgattcaat
    22441 ttttttaaca atgcaaggat ctgaagggtc gttttcggat caagtgcact ggttgcttca
    22501 tcacataata ataccttagg ttcattcgcc aaagctcgtg cgattgctac tcgttgtttt
    22561 tgtccccccg acagttgttt aggataagca gatgcttttt cttccaaacc gacaagttcc
    22621 agtagttcat tcactttttg acgacgttcc tgtttcgatt ttccagaata ctttaaagaa
    22681 aaatcaacgt tgtcaaaaat agttcggctt tccattagat tgaaatgctg aaagatcata
    22741 ccgatggcct ttctttcttt tcgcaattct ttgggagaga gctgactcag attcgtctga
    22801 ttgacaatga cttctcctgc tgttggtttc tgcagcaaat tcatcacacg aactaacgta
    22861 cttttccctg cacctgagta accgacgatt ccataaacat cgcctttttc aatcgttaaa
    22921 tctacagaat ctactgcctg tatctctttt tctttttgtt tgaaacatac agaaacatct
    22981 cgcaattcaa tcattaaaat tcctccttat ctaaaaaaag cgtcctcaag aaaatgaaaa
    23041 tgtcattttc ttgaggacgc ttttttgcgt gttaccacct catgttcaag ctgtgttcac
    23101 acacaactcc tcttcaagta cgatcatact ctagcaagat atcggtcgca gccgtcatcg
    23161 ccttacatct atgctcggga tgaattgctc gatggccatt ttccaatagt cgttccttgc
    23221 ttcttctcag ctaccgaagc tctctgtcaa aggttcttct atcgtactta ccatttcaat
    23281 gcaaataata ttcaaaaaaa aagtcctttt actaacataa actatgtcag taaaaggacg
    23341 acgtatcgcg gtaccacctt ttttcggaag tttccttccc tcaagcccaa catctcaaaa
    23401 agagagattg gcgttcgttt taacggtcga acagttccga atttgcctac ttatcgacaa
    23461 attattctcc aaggccattt tcagcttttc ttacttgact cttctcacca gccagagcct
    23521 ctctgcaaag tttccaaact tactttcctt ttcaacgaaa tcgatatttt gttgttggga
    23581 ttaatctaca tgaggaaaac tgaaaagtca agtacgaaat tcaaattatt ttttctatat
    23641 ttatttttct gtttttttat ttaacatttc aataacagtt cgaagatctt ttccttccgc
    23701 aagaagtttc aatttttcct tttcttcgac ggtataattt cggacaaaac tggaatcagg
    23761 tatcaaaaca acgcctaatc ctgctcgtga agcagctgtt gctcctacta aagaatcttc
    23821 cactgcaaag gctgaactag cttctaatcc tgttcgttcc aaagctgtca gataaggaat
    23881 cggtgaaggc ttgttctccg acacttcgtc tccgaatgta aacgtgtcca agtaatcagc
    23941 taatttaaag tgatccaaga tatctgttgc tcttttcgta acagtggtcg tagcaatgcc
    24001 tagtttcata tgacgttctt ttaagtctgc caatatttct tttgcatatg gttttaagtg
    24061 gatggctccg cttgtcagct gttgataaaa atattcttca cgcttcgctc ggacttcctg
    24121 tactttttca gggctacctg ctgctttcac taaaatatca aaactttgtt tccagttttt
    24181 tccgccccaa gcgtcaacga tttcttttgg gatatggata tcaaattgct gaaatcccca
    24241 aagccagcca tcacgatacg ttttttctgt gtcaactaac aaaccatcta aatcaaatat
    24301 tgcacctttc atctatacat taatcctttc caaaacaata cacatagttt agcacgactg
    24361 gtccaaaaag aacagaagca aagaaccagc cttctcgttt ataagagttc ttggaatcga
    24421 cggatataga ttttcttcac agctgtcaca agcgccagat aagcgatgac tgtagcaaat
    24481 aaccataacc agtaattgcc aggaagtggc atcaagccta attcagcacc aaaacttgta
    24541 aaaggaagga cagaaccgac aataattcct aatgtagtga taacaaacat ggcaaatgtt
    24601 gcgttgcttt ggataaatgg tactttcggt gtacgcagtg catggagcac taaggtttgt
    24661 gtccatagtg attcgacaaa ccatcctgca tggaataatg cgatgaaaat cactcgctgt
    24721 gaactatcca atgtatggaa acttccgccc actacagcag gacaaataac aaaatacatc
    24781 aacaagtaag tagtaatatc aaatatcgaa cttgttggac caaagtaaac catgaattcc
    24841 ccaatactag atgcattcca tttttttggc tcgtccaaat attctttatc catccgatcc
    24901 catggcaagg aaatgcagga aacatcatag atcagattca aaaacaaaag ttgtaaaggc
    24961 agcattggta aaaatggcag gaacgtactt gcaatcagca cggaaaacat attgccaaaa
    25021 ttagaacttg ctgtagcctt gatatatttc atgatattcc caaaagtttc tcgtccagaa
    25081 agaaggcctc tttccaaaat cgtcaaatct ttttctaaaa ggatcacgtc tgcagattct
    25141 ttcgcaatat ccacagctgt atctacagaa ataccgatat cagccacttt cattgcagga
    25201 gcgtcattga taccatctcc taaaaatccg acagtatgac catttttacg taaagctgtc
    25261 gtcaaacgtg ctttttgctg aggattcaat tttacgaata cttcatggtc ttcagctact
    25321 tgtgctaatt catgatcact catttccgag attttctcac cggtaaccaa ttcattgatc
    25381 tctagaccta cttgacggca cactgaacgt gtaactaatt cgttgtcccc agtcagaact
    25441 tttacagcta caccatgttc tttcagagct ttcaacgctt gtttcgttgt ttcttttggt
    25501 ggatcaagga aagcaagata accaatcaaa accatgtctg actcatcttt gactgaaaat
    25561 tctccaacga cgcttggatt ggtcttttgt gcgacaccaa tcactcgtaa gccatcttca
    25621 ttaagtgact gtacttttgc aagtacggct tcttttcgtt cttttgttaa tggtgtaaca
    25681 gtaccgccaa gatcaataaa tttagaaatg ttcagcattt cttcaatcgc accttttgtg
    25741 atcatttgtg ttttaccagc tggatcagca accacaacac tcatacgacg acgttcaaaa
    25801 tcaaaaggaa tttcatccac tttttgataa ttgatcttat ctgtatctaa agtttctgtt
    25861 gcttcatcaa tgatagccac atctaacaaa tttttcagcc ctgtttgata gtagctattt
    25921 agatacgcat ggcgcaaaac acgatcatct tcatttcctt cacaatccat atgatattca
    25981 agaatgattt tatcttgtgt caatgtcccc gttttatccg tacataacac atcgattgca
    26041 ccaaagttct ggatggcatt caaatttttg atcactgttc cttttttggc catcacactt
    26101 gctcctttga ccaaattcgt cgtaacgatc attggaagca tttcaggtgt tagaccaact
    26161 gctacagata gtccaaaaag aaaagcttct agccaatccc cttttgtaag cccattgatg
    26221 acgataactg ctggagccat caatgacata aatttgatca gtagcatgga tgttttatgg
    26281 atgcctaatt caaagcttga ttgaattggt ttttcagata gcgtttctgc tacatgacca
    26341 aatagtgttt catttccaac agaaacaatg attccttccg cacttccact gatgacatta
    26401 cttcccataa agacaagatt ttcgtaactt gtttcgcttt gctgatcgtc ttcacatact
    26461 ttcgcatgct tttctactgg atagctttcc cctgtcaatg ctgcttggga aatgaataaa
    26521 tcctttgcgg acaataaacg catatccgct ggtatcatat cccctgctga aagccgaaca
    26581 agatctccac agacgatttc ttccatagga atctctgtgt actttccatt acgttttaca
    26641 gctgccgtta ctttcacaag tgatttcagt ttttcagccg cttgattgga acgtacggac
    26701 tgaatcaacg tcattgtccc gctgacgata accatagtga agataatggc tacaccgaaa
    26761 agatctttat ctccaggagc tgctaataca tattccgtga tgaatgaaat aattcctaat
    26821 gcgatcaaca ctaatgtaaa tggcgtgatg tatgctttca atatttctac aatgaatggt
    26881 gtttttttgc catatgaaat cgcattttca ccgtaatttt ctcttgaacg ttcgatttgt
    26941 tcttctgtca atccatttgc tgatgcatgg aatagttcaa ataattcttg tttcgttttt
    27001 ccagcaaaag ctgcatagat tttttgtgta tctttctttt tttccatctc aatctctcct
    27061 ttgtgtccaa aagacagctg ttctcgctgc ttttggtctt tagctattca tcggatcgat
    27121 agagaaaaaa ctgaaagggg ctgagaacag atagataata gccctggcct ttcctctaga
    27181 tccttgtttt tcgaatgact gtcatccatt tgttctcatc tcctttacta agtaatttta
    27241 attcatgact tccaatcatt tttcgaatag ttatttttcc aattagacca cctccttttt
    27301 atttttcacc gatggggatt tgcggcaaca aaaaaacctc tcgccaaata ctcagcgaaa
    27361 ggtttgaaaa agcatattaa aaaaagcttc tcagatctca tcgttgagtt ttgacactgt
    27421 acaacgtaaa aagcagatac ctgcttttag ctaccttatg aaaagcctta tctcgacaat
    27481 tcctgttcta cccattggcg tctctcgacg tttttgggca gtagcctatg tttgtatagg
    27541 agcctcacct aacaaatctt attcggtttt ccttcgttaa tataacaact aaaaaagagg
    27601 atgtcaaatc aattttccat gtttttcata ctttttttaa aatacacacg ttatattcct
    27661 gtctcacgcg gttttatttg tctcattttc cacctcccgc tataatagaa atatagtagg
    27721 aaacgaggtg ctgttatgga aagaacactt gttattatca agccagacgg cgtgagacgc
    27781 catttagtcg gaagcatcat ccaacgtttt gaagcaaagg gactggccat tgctgaaatg
    27841 aagtttgaaa ctatgactcc tgaattagca aaagaacatt atcagcactt gactgagcgc
    27901 agtttttttg atgaactgat cgattacatg acttccggtc ctgtcgttta tcttgtgctg
    27961 gtcggcgagg aagtgatcga tatcgtccgt aagatggttg gagcaacaaa agctgccgat
    28021 gctgttccag gtacgatccg aggagactac gcgctgccgg ggactgaaaa catcattcac
    28081 gcttctgatt cccgtgatgc tgcggtaaaa gagatcgccc gctttttccc gccattcgat
    28141 ataaacaaac cgtctgaaaa agcggcgaag tgatacaaat tctaaactgc tggtctagtt
    28201 gctgggttca gcaatggcca gcagtttttt ctctaaggac ctccgttgat tctttcctaa
    28261 catatattcg agcactgtga agaattcttg gtagtctttc gtcttttctt cccctaaagc
    28321 agcagaaatc aatctttgat aataatctgc catcaatgtt tcatagatca ctgtacttct
    28381 ttctttatgt gctaagctcc gtttcatatc ttcattcaca ctacgtgcct ttttcaaccg
    28441 accattttct atataaaacg aagtcaggtt cattaaaaaa gtaaagagat actgctcatg
    28501 attgttcaac tgtgctaatc gtcgcattct ttttttgatt ttcaaataat tgttctcaat
    28561 gaaccgatca ctgaatatcc aaggaaaatc agctagaata gatagttcaa attgaccata
    28621 gtctggtatc tgcatcaagt attcttcaat gattcggcat tcataacgta aaaattcaaa
    28681 ttctgtctca gatacttctg ttttttcgac catgtgaaga ttcaaaacca aataatacag
    28741 atcttctgtt ttcttaaaat gcctacggtt attgctgatc tctttataag gatcaaagct
    28801 gtcttcttgt acccgatcta gcattcgtct ttttttcttt aactttattg gttcatccag
    28861 ctggtttcgc atccattcat attctgcaag tgtcatgttc attcgctcta aaaatgatct
    28921 caatgttaca aatgacattt ttttcactga atttgtctca atcccgacta gagaagtctt
    28981 aaaacagatt ccttccgcta attgggactg tgtcaacttc ttgttgactc gaagtttctt
    29041 gatcaattca ccatcataca taatagttct cctttttaat ttaaattttt ccacattcaa
    29101 taaatagata cgttaaaaag gaaaaataca cgaaaaaaat aaaaaaatgt ttttttcata
    29161 aaaaatacca accttcaagc attagaatgt tgtctaacta ctgaaggttg gtttgattgt
    29221 ttattgatta tttttttgct gttcaacgtc tgttcttgtt actggatata agttggttgt
    29281 tgttttatta ccattttttg aaaagacact tgtcgaatgt tcgccttttt gcttttcgat
    29341 tgcttcatta cgttccgctt catttttata gtcatatttt ttcggatcaa tcgtctcaaa
    29401 tccgtttggc acataaaacc gcaagagatt ttcctgattc agcttatctg aaagacttaa
    29461 cgcagtcttg actttttcct gatctttgga gatttcctca tcgattcctg ctgctttcgt
    29521 atcgatgatt tctcctgtct gattattgta agcttttcct cctaggacgg tgtatttggg
    29581 tgtcacaaag ttcccatttc gaaaagcaac tacttgatca tgctgagaag ataataagtc
    29641 tgtaccaaaa tgaagataat ctttatcatc gattcccaat agatgtagta atgtcggcaa
    29701 aacatcgatt tctccaccgt attcatgatt gactgtccct ttagtataac caggcatatg
    29761 gatcatcaat ggcactcgtt gcatctgtgc gttgtcaaat tcatcccatg tatctggatc
    29821 tttaccaaga gcgcttgcta aatctttatt atctgtattc gagatcccaa aatgatcccc
    29881 gtaaatcaca aagattgaat tttggtaaat accagatttt ttcaaatacg taaaaaattg
    29941 ttccaatgat tgatccagat aatgtgccgt tcgaacataa ttatctactg tgctattgcc
    30001 agtattcaaa gatggaaagt cgaaattctt gtcatccgta taataaggcg tgtggttggt
    30061 tacggaaaga aatttcgtgt aaaacggctg ttgtagatgc tcaagatatt gggcagattc
    30121 tctgaataaa tctttatcta atatcccata acctaacgtt tcgtcggatt catcaaaata
    30181 agatcgatca aagaaattgt cataacctaa gtttttatat acatgatctc tattccaaaa
    30241 actagctaca ttcccatgga aaacagcgct tgtatagcct tgcttttgtc caaggatcgc
    30301 tggtgcggct tgaaagacat tgtctgaccc aagttctgtg aataatgagc cttgaggtaa
    30361 accaaatgtg ccagtttcca acatattttc agcatcactt gtctttccct gtcctacttc
    30421 atgaaagaaa ttgtcaaagc tgatcgttgc ttgattctgg aaaatactat ttaaaaacgg
    30481 tgtgacttct tgtccgtcta ccttcatatt aatcaaaaac tgctggaaac tttctaaatg
    30541 gagaacgatc acatttttcc ctttagcgat cccaaatgtt tcgggatttg gctctgcata
    30601 atgtttcttt gtataatcta aaacttcatc aatcccatta ctgcttgcat gcgcgcgaac
    30661 actgctagtc attcctgttt tgattccgtc ataaatagta tacgcatcga ttcctagata
    30721 tttgacaata tatgaacggt caaatgttcg ctgcagcaat tgtggacggt tggcttcgct
    30781 cagcgctaga tttcctgaaa aaataagccc tgaaagacag gtaacagcga tagccatcgg
    30841 tttgccgaca gggttgcttt tgataggtat tttcttgacc ttcaaccaaa ccagtagccc
    30901 aatgaacaca gcgatatcca gccagtagat gacatcatgg ggcttcatca aagaaaagga
    30961 gcttcctgac aatccttgcg acactttcga aaagcctaat acagatttga ctgtaatgaa
    31021 atctgtgaat tcccgataaa aaataatatt caagtacaac aaaagcgtat ttaaaatatc
    31081 aatgatcaaa agaatagcta acgctggctt tggcttttta atatacaaag aaaggccaaa
    31141 aaacaataag gtagtcgcaa ttgggttgat ccacaagata aagtactgga tcgtaccttc
    31201 cacacctaat gaaaaatctg catagtaggc aatgatcgtc ttcagccaga aaaagaaaac
    31261 agctgtcaaa acgattgcta aacgattttg gcacaatttt ttaagttgtg tcacgtatat
    31321 cacttctctc tattcacatt ttttcttatt ttgctcctga aaaatgaaaa tttcctaaaa
    31381 aagttgttat cttaagattt ttttattctt tctaaagatt attccgtcca cttttcacag
    31441 cataaaaccg ctgcgatgta agcgattaaa ctaatgaaga gataaaagtc ttgtggtgac
    31501 cgcttcactc cacggtattc aaaagccagt ttctcggtat tcgtacaaaa aaagaggctg
    31561 tgacaaaatt cttgtcgcag ctccttattt cttgatgcag gacagctttt tcacaacttc
    31621 ttccttaaac ggtgttctcc tgccaactcc tcggccacaa gtcacaatat ttataaaaca
    31681 tgagaagctg ttttttgaaa ttgttccttg tggctcagag ttaaacggca ggctcaagac
    31741 ctcttgatac acggtgttca atcagctgac cctcggtatt agattatgtc aggacgctaa
    31801 ttttacaacc tcttggtaaa cggtgttcaa aagcttgcat ctgcggtaat aagcccaacc
    31861 aaacgaaaaa tataaggagc tattttttga aattgctcct tgtggctcag agttaaacgg
    31921 caggctcaag acctcttgat acacggtgtt caatcagctg accttcggta ttagctcaaa
    31981 aaacggcaaa atatgaggaa ctattttgcc gtttgtttct ctaatactca ggtcaaaacg
    32041 ctgatttcac aacctctgtt tttcattgtc cataggattg atattgtcct tgtgatgact
    32101 cattcgtaat aattgaggct tgattttctt cacttcccgt tatcgtttgt ccactgccag
    32161 aatctgaagg acttgttcct gtcgactcgt ttttttgaga agagacagtt gttttcttga
    32221 cttgttcatt tgtctttttc cattccgcta aacgatcggc gaccactttt ttgtctactt
    32281 tttcagaata agcggtgatc acttttccat ttttcaaacg ggctactttg tcgccatcat
    32341 gagtcaaaag caaaacggtc aaatgcttgt ctttaaattg atattgtctg agagaaatcg
    32401 cactaagtac gtcatcgata ttaataaatt gattttcttc ttttcctttt ggcaaataaa
    32461 tgtccaattc gcctttttcg taattggcag ttattttata ctccgcccac caataagttg
    32521 agaattcttt tttgaaatta tctactgatt ctttgcttgc tacgattttt tctgtttctt
    32581 tctgagcaag atctgctgtc atttttcctg aaaatgctgc ggataaaata agcagtaaga
    32641 aaaaaccgaa taaccaaaag agaagaaacg gtcttttttt cctcatgctt tcctccactc
    32701 ctatttaatt ttgactattc tattatatac aaaaaatgaa atagaaagac aaaaaagttg
    32761 aaaaagatcg taaataattg aacttctttt tcacaaaatg gtaagaatgg agaatttcac
    32821 gcatttgctc tcaactattc tttcttaagc ctcaaatccg tttttatctg atacgtcttt
    32881 gaaccaatga cccgattttt tgattgttct ttttccatct tgtgctaagt ctactgaaat
    32941 aaagccatat cgattcttat atgcattggt ccacgaccag ttatccatac atgtccacat
    33001 atgatagcct aaacaattgg caccttcttg aatggcttga tggacatatt tcagatgaga
    33061 ttggacaaat tcgatccgat aatcatcgtg gatcatgcca tcttctttga taaatcgtgc
    33121 ttcgttttct acacccatac cgttttcaga aataaagcag tcgatatttc cataatgatc
    33181 tcgtacattg atcaaaatat catagattcc ttgttcatag atctcccatc cgcgataagg
    33241 attcatttta cgaccaggca tttcataatt gtcgaaataa tcctcaggca ttggaccgtt
    33301 tttagtatcg attggtgttt cttttgcttt tacccggcgt ggctggtaat aattgatacc
    33361 taaaagatct actgtatttt ctttgataac cgtcaaatcc tctgcatgga tcacaggcat
    33421 gagatcaagt tcttttacta tctcaatcaa ttcacttgga aactcgcctt ttacagctgg
    33481 atcaaggaat gaacgattga agaacgcatc tgctatttgc gctgctttaa catcttcagg
    33541 gtttgattcg tctcttggat agcttggtgt cagattcaag atgataccaa taacaccacc
    33601 ttgctccatt tcatggtaag atttgatggc taacgctgaa gccaacgctt catgatagcc
    33661 aacttggatc gcttttttca tatctgactc ttctggataa tgccatcgat ataaataacc
    33721 tgcttcgact ggaacgattg gttcattatg agtaaaccat ttttttactt tcgaaccaaa
    33781 caattcaaaa caacttttgg catatttttc ataggcttca accgtttctc ggttcaacca
    33841 tccgcctttt tcttgcagat acatcggcat atcgaaatga tacagattca caaagggttc
    33901 gataccgttt tcaatcaact catcaaaata acgatgatag aaacgaacgg cttcttcgtt
    33961 gattgttcca gattcatcag gtatcaaacg gctccattgg atagatgttc gaaatgaatt
    34021 atgcccagtc tgtttcatca actgtacatc ctcttgatac ttcgtataaa cttgcgaggt
    34081 tttttcaggt cctacttgat caaagaactt ttgcggttct tttttgtacc aataatcaaa
    34141 aatgttctct ccttttccat cgcctgaaat ccttccttct gtttgtgggc cacttgctgc
    34201 agaaccccac caaaaatttg ctggaaattg atattttttc atcaaagcac ctctttttct
    34261 tttttagttc gttttagttg attccatgta tgatattttc catcacaatc actttttcat
    34321 tttcttcctc ttcttttttg attcgtttta acagctgttc tgctgctcgt tccccgattt
    34381 tatctgttgg tggcgtgatc gtgattttcg gaaggatact cagatcgttt ttatctaaat
    34441 aatcatagtg actgaacgca atatccttcc cgattctgac accttcttga ttgaaacatt
    34501 cgatggcacc aatcgacata ttgtaattgc tgacaaaaat agcagttgcc cctttttcta
    34561 ataatgcttt tgccccgtaa tagccgcttt ttctagaata gtctcctgta aagacctcta
    34621 attggatcga tggatcattt tggaccgctt ctttggctcc tgctaaacgt tctcttgcta
    34681 cgtagtctgt ttgagtggca gcaataaatc cgattttttt atgtccttgt tcaccatgat
    34741 gagcgatcac ttttgctaca ctttctcgat cattcactaa tattgtatca atacctgctg
    34801 gtccttctgg acaattcaat gcgataactg gaatactcat ttttgtgagc atttcaaatc
    34861 cagaccactc ttcttcggat aagaagacaa tcagcccatc gatcacatgc ttcatcaggt
    34921 attcaatttt ttgttcaatt ttttctggct gatcggcaaa cccgcttaat aataagctat
    34981 acccattttc ttcagctact ctttcgatcc ctgagacaac ttccgaccca aaacggctgg
    35041 aaatcccgtt tatcaaaagt ccaatagaga agcttcgatt attcttcaac cctttagcaa
    35101 tgatgttttc tttatagtcc aacgctgaaa tcgcttctgc tatttttttc atgttctttt
    35161 ccttcagttg ctgaccattc aagtaacggg aaactgttcc cactgaaaca ccagccatct
    35221 tagccacatc acggatcgat gccatacatt ctcactcctg ccagttacat ttgatttctc
    35281 tttcttgttg ttcgattatg atgaccgcat tctttgcata gtgttgcttg tcatcaatat
    35341 ccatataact aaagtcttca gtagagcaac ttcctctcac tattaattat acttaaacaa
    35401 gtatttgaac cggttcattt ttaatatagc atttttttaa aagattgcaa cactttttta
    35461 aaacgctttc tgaaagtggc ggattttttg cctttttaaa attttattct aaaatttact
    35521 ctatttgtgg gtgttttgtg cgtttttctc ttccatccgt ttgaagtttt acattccaat
    35581 ggtataattt ctttatccta tcaaatgggg gaagtatttt gaagaaatta atcgtactat
    35641 ttattttgtc tgcgggactt ttgacattga ctggctgtga tttgtttggc ggctctgacc
    35701 aatcctcgga cgaaacaacc gattcttctg tcttaaaagc ggaaaaagca gataccacca
    35761 acagtgtata tacgctaaaa gtacgtaaag atatggattt atccgcggga cagttgacat
    35821 ttacagataa aaaaatggaa tggacacgca cgtatcagac acaaggaact gattcttctg
    35881 aatcatctga agaaaaaaca gtgctgacag atatcaagat cactaccaaa gatgacgaat
    35941 atattatttc aggaaaagaa aataaaaaag aaacaacagt catatttaca aaaatcggta
    36001 attaccgttt gaaggatgag gatggcaaca tctacagtct atagtgccgt ctgttggatc
    36061 ttcttttgtt tctccccttc ttttctgcta tagtaaagaa gcaagatgat tgtaaaggag
    36121 acgaaatgga tgatcgatag tcctgattat tgtacatgta ataacaacaa aaatatccat
    36181 acagaattta atgaccaagg aagcttgagc atatgcgaca actgtcacaa actagtcaaa
    36241 gattcattta aaacatttga atcttatcct gttcaaaatt atgtaaaaag tagaagaaga
    36301 taaacaaatc caagcaaaac tcactatggc tgatttttat gaacttcaaa ctcagcttct
    36361 tcctttgatc aagcttcatc agtaaaacaa acagtggatc atttcagttt acaaatcaaa
    36421 gagtaaagat ttatttattt caaatatttg aatataaaat aaccaaacga tagaaaggct
    36481 tattctacat cacgtagta
//
LOCUS       DAZKKZ010000027        36112 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.027, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000027 DAZKKZ010000000
VERSION     DAZKKZ010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 36112)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36112)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36112
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.027"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..1382
                     /locus_tag="ACG8LA_001383"
     CDS             <1..1382
                     /locus_tag="ACG8LA_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="2-oxo acid dehydrogenase subunit E2"
                     /protein_id="HFQ0203689.1"
                     /translation="GVAAESQTPAKPAAEPTVDTESAGSSSEGVFQFKLPDIGEGIAE
                     GEIVKWFVKPGDTINEDDTLLEVQNDKSVEEIPSPVTGTVKNVIVPEGTVANVGDVLV
                     EIDAPGHNSAPSTSAPSAEAPKEKVETSGSASVVEAADPNKRVLAMPSVRQFAREKDV
                     DISQVTATGKGGRVTKEDIENFLAGGPSSAPAKSEAPEAAAPKEAAPAAESKPAAPAK
                     PFKSNLGDLEERVAMTPTRKAIAKAMVNSKHTAPHVTLHDEVEVSKLWDNRKRFKEVA
                     AANGTKLTFLPYVVKALTATVKKYPVLNASIDDANQEIVYKHYYNIGIATDTDHGLYV
                     PNVKDADRKGMFAIADEINEKAKLAHDGKLSAEDMRNGTITISNIGSVGGGWFTPVIN
                     YPEVAILGVGTIAQQPIVNAEGEIVVGRVMKLSLSFDHRIVDGATAQQAMNNIKRLLA
                     DPELLMMEG"
     gene            1390..2796
                     /gene="lpdA"
                     /locus_tag="ACG8LA_001384"
     CDS             1390..2796
                     /gene="lpdA"
                     /locus_tag="ACG8LA_001384"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004148 - dihydrolipoyl dehydrogenase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HFQ0203690.1"
                     /translation="MVVGDFAVELDTVVIGAGPGGYVAAIRAAEMGQKVAIIEREYIG
                     GVCLNVGCIPSKALIAAGHHYQESLDSEMFGVTSENVKLDFAKTQEWKENKVVHTLTS
                     GVGFLLKKHKVETIEGEAFFVDDHTLRVIHPDSAQTYSFNNAIIATGSRPIEIPGFKF
                     GGRVLDSTGGLALKEVPKKFVIIGGGVIGAELGGAYANLGAEVTILEGSPQILPTYEK
                     DLVKLVEDDFKKKGVTVVTNAMAKEAVDNGDSVTVKYAVDGKEESVTADYVMVTVGRR
                     PNTDDMGLEQAGVEVGERGLITVDKQGRTNVPNIYAIGDIVPGAALAHKASYEAKIAA
                     EAISGKKVAVDYKAMPAVAFTDPELASVGMTIKEAKDAGIEAKAYKFPFSGNGRALSL
                     GKTEGFIRLVTTIEDNVLIGAQIGGVGASDMVSELALAIESGMNAEDIALTIHPHPSL
                     GEIVMDASELALGLPIHI"
     gene            2958..3233
                     /locus_tag="ACG8LA_001385"
     CDS             2958..3233
                     /locus_tag="ACG8LA_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HFQ0203691.1"
                     /translation="MQEYQYPLDLDWTTDEMVIVMKMWEDLERANEKGINNEAFLKTY
                     QQFKTVVKSIGEEKRLGREFEKASGYSLYRTVQQAKKNPNKTLRMNG"
     gene            3239..4006
                     /locus_tag="ACG8LA_001386"
     CDS             3239..4006
                     /locus_tag="ACG8LA_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HFQ0203692.1"
                     /translation="MEQMIDHIKSWLEEAGEKIKSSQQTLTISQKSNRTDLVTNVDRN
                     IQNFLIEKIHSFDPEAKILAEEEGCNQLSDLDGRVFIIDPIDGTLNFVIEGENFCIML
                     AVYESGVGKLGFIYDVMRNELFWGGKGIGVYKNDEPLPRPANKSLSEGLLGVNSYLFG
                     HNKYGIREIAESSMGTRMYGCAGLELVAILKGNHIAYISNLSPWDYAAGNVLLEEFGM
                     VTSGLFGTPLTFEKREYYLAGTSCAYAEIADLLKKEG"
     gene            4174..6003
                     /gene="typA"
                     /locus_tag="ACG8LA_001387"
     CDS             4174..6003
                     /gene="typA"
                     /locus_tag="ACG8LA_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0006950 - response to stress [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HFQ0203693.1"
                     /translation="MNYRNDIRNVAIIAHVDHGKTTLVDELLKQSDTLDAHTQLQERA
                     MDSNALEKERGITILAKNTAVDYKGIRVNIMDTPGHADFGGEVERIMKMVDGVVLVVD
                     AYEGTMPQTRFVLKKALEQHITPIVVVNKIDKPSARPEHVVDEVLELFIELGADDDQL
                     DFPVIYASALNGTSSLSDDPADQEPTMAPIFDTIIEKIPAPVDNSDEPLQFQVSLLDY
                     NDYVGRIGIGRVFRGTIKVGDQVALIKLDGTVKKFRVTKLFGFFGLKRLEIQEAKAGD
                     LIAVSGMEDIFVGETVTPVDHQDALPILHIDEPTLQMTFLVNNSPFAGREGKFVTARK
                     IEERLMAELQTDVSLRVEPTNSPDAWTVSGRGELHLSILIENMRREGYELQVSRPEVI
                     EKEIDGVKCEPFERVQIDTPEEYMGSVIESLSLRKGEMQDMVHTGNGQIRLTFLTPAR
                     GLIGYSTEFLSMTRGYGIMNHTFDQYLPMLPGQIGGRHQGALVSIDTGKATTYSIMSI
                     EERGTVFVEPGTEVYEGMIIGENSRDNDLTVNITKAKQMTNVRSATKDQTSVIKKPKQ
                     LTLEESLEFLNDDEYCEVTPESIRLRKQILEKNAREKASKKKK"
     gene            6264..8036
                     /gene="recQ"
                     /locus_tag="ACG8LA_001388"
     CDS             6264..8036
                     /gene="recQ"
                     /locus_tag="ACG8LA_001388"
                     /EC_number="5.6.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0009432 - SOS response [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase RecQ"
                     /protein_id="HFQ0203694.1"
                     /translation="MNDLLKQYFGYDEFRPGQKEIIQKVIDQENVLGIMPTGSGKSIC
                     YQLPALLLDGLTVVVSPLISLMKDQVDAANQLGIPATFINSSLDGYETARRFQEIDRQ
                     QYRLLYIAPERFIMPDFIQAMKRWNVRMIAIDEAHCISQWGHDFRPSYLQMANQLDQL
                     PNRPVIVALTATATVQVAADIKRLLKIPENNHIQTGFERENLRFQVIKDQKKEQYLIE
                     YLKINKNQSGIIYAATRKEVDRLYHLLKKFDFSVGRYHGGLNENERTEMQEAFLYDRL
                     QLIVATNAFGMGINKSNVRFVIHYQIPGSLEAYYQEAGRAGRDGLSSEAILLFSPQDI
                     QVQKFFIQQSQREEGQKQKEYEKLKAMTEYVYIESCLQQYILNYFGETSSPCNRCGNC
                     LDDREIVEVTTEAQMVLSCLKRMGENYGKQMLMKVLAGSKEQKLQALGFGHLSTYGLM
                     KNQSQKETMQLIEYLISNGYLLTINGEYPVLKVTERGIQVLKGQESVYRKEPKKVQQL
                     SDEETDTLFEVLRELRTDLASEAGVPPYVVFSDSTLKEMSRIRPSSRLEMLQIKGVGQ
                     SKLDKYGEAFLSRIKNADSNVLDK"
     gene            8150..8452
                     /locus_tag="ACG8LA_001389"
     CDS             8150..8452
                     /locus_tag="ACG8LA_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlaN family protein"
                     /protein_id="HFQ0203695.1"
                     /translation="MDSLSKKLAIQVLNDEAERIKRLIRNQNNSLCISQCKAFEEVVD
                     TQMYGFSRQVGFAVRIGVIGKNEGQLMLSELERELNQLYSEVYQEIYDKKEVGKEE"
     gene            8455..9618
                     /locus_tag="ACG8LA_001390"
     CDS             8455..9618
                     /locus_tag="ACG8LA_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HFQ0203696.1"
                     /translation="MPKKVKKRHLLDYSILIPYLILCVLGLIMVYSSTSYLLLENGQN
                     PSASVINQSIFWVLSLIAIALLYKMKTDVLKNQRLIMAAIAVLTILLLIVVFFGKEIN
                     GAKGWLQIAGFSIQPAEYLKIISIWYLSLTLSKRQNSVQKDFLGTVKRPLAMVIGLTA
                     LVAILPDFGNAAVIFLIILVLLLASGVNYVYTLIVGVGGFCLSTFTIWLINITNGKIL
                     PGRLQYIYNRFAIYQNPFSDELNKGHQLVNGYYAMFNGGLFGRGLGNSIQKKGFLQEA
                     QTDFIYAIVVEELGVIMGILILALLFFMIVRIVLVGIRSKDPFNSLLCIGIGAMFLIQ
                     VFVNLGGITGVIPLTGITFPFLSQGGSSLLMLSICVGFVLNISADEKRKSLGL"
     gene            9644..13072
                     /locus_tag="ACG8LA_001391"
     CDS             9644..13072
                     /locus_tag="ACG8LA_001391"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004736 - pyruvate carboxylase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0009374 - biotin binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006090 - pyruvate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase"
                     /protein_id="HFQ0203697.1"
                     /translation="MKKVLVANRGEIAVRVFRACTELGIKTVGIYAEEDEYSVHRFKA
                     DEAYLVGQGKKPIDAYLDIEGIISIAKECGADAIHPGYGLLSENLNFAQRCEEEGIIF
                     VGPKLHHLDIFGDKIKAKAAAIEAGIASIPGTDGPIASIDDALEFAKQYGYPIMIKAA
                     LGGGGRGMRVAHDEKSAREGYERAKSEAKAAFGSDEVYVEKYIANPKHIEVQILGDTH
                     GNVIHLFERDCSVQRRHQKVVEVAPCVSMNEQQRQKICQAAVQLMKYVGYVNAGTVEF
                     LVEGDDFYFIEVNPRVQVEHTITEMITDIDIVTTQLLIAQGLDLHKEIGLPQQEGIKL
                     NGSAIQCRITTEDPLNNFLPDTGKIDTYRSPGGFGVRLDVGNAYAGYVVTPYFDSLLV
                     KVCTHGATFETAIQKMERCLKEFRIRGVKTNIPFMLNVITHPEFQSGNAKTTFIDSTA
                     TLFEFPRLRDRGNKTMKYIGEITVNGFPGIESGEKPFYEEPRMPKDLITRTDYVTAKN
                     VLDAKGADALVEWIKGQENLLLTDTTFRDAHQSLLATRVRTKDFKQIARLTGEGLPEL
                     FSSEMWGGATFDVAYRFLNEDPWQRLRKIRSLMPNTLLQMLFRGSNAVGYSNYPDNVL
                     VEFVKEAAAQGIDVFRIFDSLNWTPQMEKSIQAVRDTGKIAEAAICYTGDINDPSRAK
                     YNVQYYKDMAKELEQLGAHIIAIKDMAGLLKPQAAYRLISELKETTDLPIHLHTHDTS
                     GNGIITYSAASKAGVDIVDVAMSAMSGNTSQPSMSSLYYALVNGPRLPEITIENAQKL
                     NHYWEDVRMYYKPFENGLNAPETEVYMHEMPGGQYSNLQQQAKAVGLGHRWDEIKQMY
                     HTVNLMFGDIVKVTPSSKVVGDMALFMVQNDLTEEDIYEKGETLSFPESVVTFFQGEL
                     GQPVGGFPKKLQKIILKGRPALNERPGLLAESVDFNEVKKELAEKIGYEPKQDEVLSY
                     LMYPQVFLDYQKAYNQFGDVTLLDTPTFFQGIRLGETINVQIERGKTLIIRLDEIGEP
                     DIEGNRVLFFNLNGQRREITIKDNSIISTVQTRLKAEPTNREQIGATMSGSVLDVLVK
                     KGDNVKKGDTLMITEAMKMETAIEARFDGEVAHVYVSSGDTISSGDLLIEVTEK"
     gene            13093..14217
                     /locus_tag="ACG8LA_001392"
     CDS             13093..14217
                     /locus_tag="ACG8LA_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CAP-associated domain-containing protein"
                     /protein_id="HFQ0203698.1"
                     /translation="MKRLGLFWLILLLVIVAFYMEPVLFPPKLEVKENSDQQISNQMT
                     TWKYQELKATGFSTYIGKPIDQLEKDFGQAYDRLTSGFGFETRYYENKASHLTFEANI
                     QDSRVTTVKVLQTGPADIAPFYLGMTMQDLTKITTIYTNFTFEYHDTEVGIELMEEDM
                     NYRPLIAFDNDTFAILFFDQTTNGLFSVVYLDKDSLLKLLPYQVFGEGLPHYQADKSA
                     DWESINRVKERKSTTLLNMLRREDELPIYNQTLAFQNHSQLLLHDFLTRPEEILSEER
                     MADWQKSLGSAQTTVKFSLTNDELEKLISKQKLENTSGLFIHPAIDATFSFLYWYSDP
                     YNHDRFMDPGTDSVGIAFSKENMLVLLQEENGESSDSSDR"
     gene            14198..14644
                     /locus_tag="ACG8LA_001393"
     CDS             14198..14644
                     /locus_tag="ACG8LA_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HFQ0203699.1"
                     /translation="MIAVIVNEELFQLEDQCLQVAEMIKKSKTMASYLEHKQSMEESA
                     KVCQLKEAFLSKKEAFENVAAYGEYAPDYREKKRAVRKAKRQLDMDEHVAAFRYSETQ
                     LQSLLDQIVQVLAEEVSNEIKVDAGSPFFETKKHFGCGGNCHAIRQ"
     gene            14628..14966
                     /locus_tag="ACG8LA_001394"
     CDS             14628..14966
                     /locus_tag="ACG8LA_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HFQ0203700.1"
                     /translation="MQLDNSEFEITKRRGLIVWVYSLKQLKNLKKFGLLHYVSRRMKY
                     VVLYLNEETLEETEERIRKLHFVRNVERSYRPDIEMNFAEKIGNKTVLKDEGFEIEEL
                     NTEIRLAEHL"
     gene            15085..15645
                     /gene="rsmD"
                     /locus_tag="ACG8LA_001395"
     CDS             15085..15645
                     /gene="rsmD"
                     /locus_tag="ACG8LA_001395"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052913 - 16S rRNA
                     (guanine(966)-N(2))-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0031167 - rRNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HFQ0203701.1"
                     /translation="MRIISGNYGGRRLKSLAGANTRPTTDKVKESIFNMIGPYFDGET
                     VLDLFAGSGGLAIEAVSRGCSHAVCVDKNYQALKIIKENIEITKEPEKFTTIKLDADK
                     AIERLAAEKQQFDYLFLDPPYAKQKIIDQIHKMEELGLFSKTAVIVCETDKTVELPET
                     VAGFHQIRKQIYGITAVTIYRKEGNQ"
     gene            15642..16133
                     /gene="coaD"
                     /locus_tag="ACG8LA_001396"
     CDS             15642..16133
                     /gene="coaD"
                     /locus_tag="ACG8LA_001396"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004595 - pantetheine-phosphate
                     adenylyltransferase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HFQ0203702.1"
                     /translation="MKRALFPGSFDPFTKGHLDTVERAAKLFDEVVIGVFINTSKKSL
                     FPPEERMTLITKAVSHLPNVKVMHQENQLTVETAKEIGADALIRGIRSIKDFEYEREI
                     AQMNHHLYDELETVFLLAKPEYSHVSSSILKEVLHFGGDVSSYLPPVINEALAGKRES
                     NES"
     gene            16123..17166
                     /locus_tag="ACG8LA_001397"
     CDS             16123..17166
                     /locus_tag="ACG8LA_001397"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SepM family pheromone-processing serine
                     protease"
                     /protein_id="HFQ0203703.1"
                     /translation="MKAKQWLKTVLIIIFGMLIIGFVVVPLPYYVESPGATIDLKELI
                     TVNDKEDKGSGSFSLTSVGIRQATGFLALKAKMTPFEELISEEELTGGATNEEYNQMQ
                     QYYMDSSQNAAIEQALKLADKPYKMEFKGVYVMSVEKTSNFFGKLSVGDTVTKVDGKS
                     FQSTEAFMDYVKSQKVGQTIEISYLHNGEEKTASGDLIELPTDKKAGIGITLTDHTEI
                     ESDTDVRINSGSIGGPSAGLMFTLEIYEQVTGKNLRHGKQIAGTGTINSEGEVGRIGG
                     IDKKVASADKAGVEIFFAPDDTISDDVKKEYPEIKTNYEEAKAAAKKLNSSMKIVPVK
                     TVQEALDYLEKMK"
     gene            17325..18053
                     /locus_tag="ACG8LA_001398"
     CDS             17325..18053
                     /locus_tag="ACG8LA_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016925838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HFQ0203704.1"
                     /translation="MKGVMNDFYWSFFEKRTMIEKISKKILASPKLIIWMSMIVLIFC
                     IASGFLLSNLLFYRETEETAAKEILSSFSSSGEDPSAEGNDVEEDARPKVMYTDIKGS
                     VKEPGIYSFSSEERVYDVLKRAGGLLEEADSDRINFSAKIEDQQVLYIPAVGEELPEH
                     LDQLASSEGKQPTADSEPPKININTATPSELQQIPGIGSVKAQEIIRFREENGSFQKV
                     EDLQEISGIGEKTVEKLKNFVTIK"
     gene            18169..18414
                     /locus_tag="ACG8LA_001399"
     CDS             18169..18414
                     /locus_tag="ACG8LA_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HFQ0203705.1"
                     /translation="MIVRKETLKKPMLNVYLQNKISGIHIMNTAVSGNNSQALRERFA
                     KDVLSYTADKVFILIGTNDLAEHKQLSKETYQKICSG"
     gene            18411..18629
                     /locus_tag="ACG8LA_001400"
     CDS             18411..18629
                     /locus_tag="ACG8LA_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HFQ0203706.1"
                     /translation="MIVQLKKDYSSDHAFFITPPAVDETKQKYRNNKLIKEYISVLTE
                     VAKRHDCEVSIFIRNFLNKWIRRIFIMG"
     gene            18765..19304
                     /locus_tag="ACG8LA_001401"
     CDS             18765..19304
                     /locus_tag="ACG8LA_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComE operon protein 2"
                     /protein_id="HFQ0203707.1"
                     /translation="MLEKSSKACDTNKEKVTDKSHNERIPWDQYFMAQAVLLSLRSTC
                     TRLEVGATLVREKRIIAGGYNGAVSGDVHCIDEGCYVVDGHCLRTIHAEMNALLQCAK
                     LGIPTEGSEIYVTHFPCLACTKALLQAGVKGINYLHDYRNDPYAQALIEQLGVSVHQV
                     ALDSQHFSKLQNELTGKHV"
     gene            19297..21570
                     /locus_tag="ACG8LA_001402"
     CDS             19297..21570
                     /locus_tag="ACG8LA_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0009290 - DNA import into cell involved in
                     transformation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HFQ0203708.1"
                     /translation="MSSVLERHVRNRLIFPAITSMIICLLYYTDNWGYRLLLAGIFLW
                     FSLKEGRFIAYLCILCSITVSISYRLQEYSFLEEKTTSAQITVFTDTIRANGNFLTME
                     GRLSENKQKLQLSYQVNTEAELKTWLNFRGKGIELTAEGEFISPAKKRNLYNFDQEAY
                     FRNHRISGRFQIQKIEQITMQNHWRNWLQRKRGSFISFVQSEFPQKTSVYINSLLWGY
                     KDAGFREPEEIFRESGLLHLFSLSGLHIQFYLGWLYYLFRRIGWPLHVSIIPLSLLTI
                     CYVSIAGSSISVLRASLLFLLRLLVKLLNKHYSTMDLFAVVFWLLLLFDPRFLFHAGG
                     QLSFFMSFLFILISFDGDWLKKTASHVLFTMITMPLIVWHFYEWPILGSLFTLLIAPV
                     FKFLFLPGVLFLTLFNRWLPETLLLLIEEGLILFERIIDFSSGSSLIIGRLPLVLSGM
                     YIFGLLICMDRLKEQPVKHLFYVGLFSFIFLTLPFLRFSSTIAFIDVGQGDSIFLQSP
                     FRKETILIDTGGQLHFEREKWAQGMIRPPAERNIVPYLKGQGISVIDKLILTHDDTDH
                     VGELPTLSQHFTIKKIYIGWGAGRNEPLQRHLSEAQKNGTEIIEIKHGDRISGYYDLY
                     VLTPFEKGEGRNEDSIGLWMEYNNRRFLFLGDLNQAMEKQLLLIYPNLKADVVKLGHH
                     GSRTSSNTDFLSHIEAKHGIISCGVNNRYGHPHSEVLETLEENQIKTWRTDQQGMITY
                     RWHPVFHPHGLVETMID"
     gene            21608..22654
                     /gene="holA"
                     /locus_tag="ACG8LA_001403"
     CDS             21608..22654
                     /gene="holA"
                     /locus_tag="ACG8LA_001403"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HFQ0203709.1"
                     /translation="MVSNLSIQAELQKIRKEKLASCYLILGTEKFLQDQVRTEIVKKI
                     QLEGEDDLNFLSFDMENASLDEVVAEAETLPFFGDQRLVFVENPYFLTGEKVNNGIEQ
                     NTDLLTAYLKEPLESTVLVFFAPYEKLDERKKVTKQLKKTAIIINVQQLNEKEVRQYL
                     MNTLENSSIKMERSAIDLFLRLTDLDLSKMMRELQKLVLYGQNQQQITVREVEELVPK
                     TLEHNIFDMTQYILKGKTEQALRLYEDLVMQGEETIKINAILLSQLRLFLQTKFLVKI
                     GYQQANIAETLKIHPYRVKLAMQEVKKFDEHLLVQLFDQLVEMDYQIKTGQIEKELSF
                     QLFVLRTGQLLRNR"
     gene            complement(22743..22997)
                     /gene="rpsT"
                     /locus_tag="ACG8LA_001404"
     CDS             complement(22743..22997)
                     /gene="rpsT"
                     /locus_tag="ACG8LA_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HFQ0203710.1"
                     /translation="MPNIESAIKRVRTSENANVKNSSQTSAMRTAIKKFEDAVASGAD
                     NVDALYKEAVKAIDMAESKGLIHKNKANRDKSRLSKKIAK"
     gene            complement(23397..23666)
                     /locus_tag="ACG8LA_001405"
     CDS             complement(23397..23666)
                     /locus_tag="ACG8LA_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0203711.1"
                     /translation="METFEGLLIDTYVLQEQPMMLTGINLQLEDRVINGLLKDRYLAK
                     YILRLPLNKYVLEVSGKWNRRNQLVIKKMLIKNIDEYIKIIGTPE"
     gene            complement(23928..24056)
                     /locus_tag="ACG8LA_001406"
     CDS             complement(23928..24056)
                     /locus_tag="ACG8LA_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0203712.1"
                     /translation="MFEKLKYFIGTIGWFLLAVLLILGLAYLLFPDLIQNVFDTAF"
     gene            complement(24136..24591)
                     /locus_tag="ACG8LA_001407"
     CDS             complement(24136..24591)
                     /locus_tag="ACG8LA_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF441 domain-containing protein"
                     /protein_id="HFQ0203713.1"
                     /translation="MESWLFLGIILLVAILAKNQSLMIAAAFVLIMKLIPASRSFFPW
                     LQGKGINIGVTIITAAILIPIATGEIGLRDLLEAFKSPIGWVAVFCGGLVAVLSSKGV
                     GLIASDPQITVALVFGTILGVVFLRGIAAGPVIASGITYCILQVFALGK"
     gene            complement(24729..26657)
                     /locus_tag="ACG8LA_001408"
     CDS             complement(24729..26657)
                     /locus_tag="ACG8LA_001408"
                     /EC_number="7.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015662 - P-type ion transporter activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0019829 - ATPase-coupled monoatomic cation
                     transmembrane transporter activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HFQ0203714.1"
                     /translation="MTNQKKAFAATIGCLLFMIFGFIFDRFSLTITPLFYISAIIIGG
                     YKQTSEGLKELWNDRTLNVDLLMALAAIGACLIGNYFEGAMLTFIFCLSGALEEYTTN
                     KSQKEITALMNLQPQKAQLLKENGQMQEVDVSQLKVDNLVFVAKGAAVPIDGFLESTQ
                     ATIDESALSGESVPVEKYLGDEMYAGTLNQGNPITIRVTKTSSETVFAKIIQLVEEAQ
                     NTPTQTASFIERIENNYVKLILLAVPLMILLPHFFLGWSWDESFYRGMVLLVVASPCA
                     LVASATPASLAALSNSAKNGILIKGGIHLEKLSELKAIAFDKTGTLTKGKPVVTDSFF
                     FDEKDLAQQLLVAMEQKTTHPLAHAILQYFDCTIPEEIQYLPIEEITGFGLQTTYLGA
                     QWKVGKHAYDPETMIISKEIAEMIERLENQGKTVIYLSKDQQLIAVLGLLDIPKANTQ
                     QVISYFKSQNIHTSMITGDHSGTAKAIAEQVGIEHYYASCTPEEKTQLVKKENELYQV
                     NAMVGDGVNDAPALAAASLGVAMGQGTDAAMDIADIVLMKSDLNKFVYSHRLSLKMRR
                     IIKQNIIFSILVILLLIASNFLQFLNLPLGVVGHEGSTILVILNGLRLLRPLPDLSDS
                     SKKCKSCPLYKARLSSVK"
     gene            complement(26854..27687)
                     /locus_tag="ACG8LA_001409"
     CDS             complement(26854..27687)
                     /locus_tag="ACG8LA_001409"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0050380 - undecaprenyl-diphosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0016311 - dephosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HFQ0203715.1"
                     /translation="MFFANIIKAVILGIIEGITEWLPISSTGHLILADEFIKLDASSQ
                     FMSMFNVVIQLGAILAVVVLYFHKLNPFSPSKSTVEKKDTWTLWFKVIVACIPAIIIG
                     LPLDDWLEANFHKFLPVAIVLIVYGIAFIIVEKRNKNKTPRWTSLNDFTYQAALLVGL
                     FQVLALVPGTSRSGATILGSILIGASRFVATEFSFFLGIPVMFGASGLKIVKYLAEGN
                     SFKMEETVVLLVGTFVSFVVSVLAIKFLLSYLKKNDFTAFGWYRIILGIILIGYWFIA
                     M"
     gene            complement(27879..28583)
                     /locus_tag="ACG8LA_001410"
     CDS             complement(27879..28583)
                     /locus_tag="ACG8LA_001410"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HFQ0203716.1"
                     /translation="MTETTLYIVRHGKTMFNTIERVQGWCDTPLTKQGQEGIHYLGRG
                     LKNVDFSFAYSSDSGRAIETARIILGEHSKGKEIPYFIEKRIREWCFGSLEGGYDMEM
                     WGVIPRVLNFKTYDEMFTTEVSFEQIANAVYNLDTAGWAETYETLRDRVWTGFEDIAH
                     HCEKNGGGNVLVVSHGLTIAFLLNLIDPKQPVRAGLLNGSVTKVTYANGRFSIHGIND
                     TSYIDNGKTHSRDSFL"
     gene            complement(28606..29232)
                     /locus_tag="ACG8LA_001411"
     CDS             complement(28606..29232)
                     /locus_tag="ACG8LA_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HFQ0203717.1"
                     /translation="MHIERLKTGMIEENCYLVYNEEALLIIDPGEDAERIKQEIKKTN
                     QQPVAILLTHTHYDHIGAVEPLRAYYQIPVYVSPLEQKWLGDPILNLSGLGRHDDIAD
                     VIVSPAEYEFEMKTYTLGNMSFRVVPTPGHSIGSVSFIFDDFVVSGDALFRGSIGRTD
                     LYTGNLEQLLHSIRTQLFVLPDEFAVYPGHGDATTIEQEKRTNPFFNR"
     gene            29558..31933
                     /locus_tag="ACG8LA_001412"
     CDS             29558..31933
                     /locus_tag="ACG8LA_001412"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase"
                     /protein_id="HFQ0203718.1"
                     /translation="MIKQSKISVRHLVEFILRRGSIDNRKKSNHTALEGARIHRKLQK
                     DAGENYEKEVFLKTTVQLDEYYLIVEGRADGIFKRDGIYYIDEIKTSEPRFEDLEPEQ
                     VELFFHQARVYAYIYSQEHDLQEINLQLTYFQTAEEVITRKVEHQTREQLETFFKKLT
                     EDYKEWLVFQENWRTVRNASLMALKFPHDEYRKGQRELAVAAYKTIRTKQKLFVEAPT
                     GTGKTISTLFPALKAVGEEEGEKIFYLTAKTITRQVAEDAMTALKDTGAEVKSVTLTA
                     KDKICFLDETTCNPDQCPYANGYYNRINEGLWDLLNHENQITREVIETYARKHTLCPF
                     ELSLDVSIWCDVIIGDYNYLFDPTVYLRRFFEDEKNEDYLFLIDEAHNLVNRSREMYS
                     AELSYEKTKRSKEAIPKEFKKLHRRFNKLLKEFDSIREIAKEDHWDYHHQKAPAESLV
                     KAGYQLSEKIKEWLAEFPEHPSQEQLLPYYFDLLHFLKVSEFYDDHYETTVEKTYRDL
                     IVKEFCIDPSLFLEQSLDKGKSSILFSASFSPLSYYQETLGGQKSLAYKLPSPFPEGN
                     QQVFIANYLETTYRKREHSLAKLVETIHAFADGKVGNYFVFFPSYQYLDLAVEAFRQQ
                     YPDSNVLIQETDMNEEERERFLTKFQTNPAETLIGFCVLGGIFSEGIDLRGDRLIGSM
                     IVGVGLPQMNHEQELIKSYYDEKEHLGFAYAYQLPGMNKVLQAGGRVIRGMADQGIVV
                     LADQRFSSFSYRRLFPQHWQTAREVRSVGELEEGIQRFWLSKEAVNQKNEE"
     gene            complement(31957..32448)
                     /locus_tag="ACG8LA_001413"
     CDS             complement(31957..32448)
                     /locus_tag="ACG8LA_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YajQ family cyclic di-GMP-binding protein"
                     /protein_id="HFQ0203719.1"
                     /translation="MAKDASFDIVSEVNTEEVKNAIQQTTKELSNRFDFKDSTVEIKL
                     ENSNLVVLSDDDFKIEQIKDVLFGKLIKRNVPIKNIHFSESEHALGGKARQTADLVNG
                     IDRENAKKITTAIKNEKLKVKAQIQEDQIRVTGKNRDDLQAVIALLRKLDLPIELQFT
                     NYR"
     gene            32635..33555
                     /locus_tag="ACG8LA_001414"
     CDS             32635..33555
                     /locus_tag="ACG8LA_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFQ0203720.1"
                     /translation="MTAYHKNERLKKIVVILITGLTAAVALNYFLIPANVFSAGMNGI
                     AQIISSLLYEWFHIKIDTGTFIFLLNIPVFVLGFLKVGKRATILSFVNVVCVSVMTML
                     LPVGQITDNILMNALVGGVLLGLGVGLSLKMGFTTGGMDIISLVLSQTTGKTVGNYML
                     ILNGIIVVIAGFFFNWESALYTIISIYAMTQVIDAIHTSHQKVTAMIVTVKPEEVTEE
                     LAKRMVRGMTLLPSVGGYSKKQGNMIMMVITRYEMYDLDQIVHEIDDDAFINILPTHS
                     VFGRFANENEQKMYRTTGVLPEIKNRSQKK"
     gene            33709..34053
                     /locus_tag="ACG8LA_001415"
     CDS             33709..34053
                     /locus_tag="ACG8LA_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HFQ0203721.1"
                     /translation="MSEANQERSGQEIELIKERILAALEMVIDPELGIDIVNLGLIYD
                     IEFNPENGETVIKMTLTTMGCPLADILTESIHDALKEVPEVTKAEVKLVWYPAWTTDK
                     MSRYARIALGIR"
     gene            complement(34243..34743)
                     /locus_tag="ACG8LA_001416"
     CDS             complement(34243..34743)
                     /locus_tag="ACG8LA_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFQ0203722.1"
                     /translation="MKLIKLWEADLKKAYQLQTSFGPNESGFINNAYGYTFAEFLDYV
                     KKCEKTSLGIDLPESYVPATVFILESDEHEYVGIFNLRHKLNETLRNGAGHIGYGISP
                     NYRKKGYATQGLALVLQEAKKIGIDEALLSVNKKNLGSLKAQQKNGAAIYREDEKEYY
                     TKIKLM"
     gene            35271..35354
                     /locus_tag="ACG8LA_001417"
     tRNA            35271..35354
                     /locus_tag="ACG8LA_001417"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35305..35307,aa:Leu,seq:cag)
     gene            complement(35678..>36112)
                     /locus_tag="ACG8LA_001418"
     CDS             complement(35678..>36112)
                     /locus_tag="ACG8LA_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M23"
                     /protein_id="HFQ0203723.1"
                     /translation="YSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEPVQAEQPVVQET
                     VQTETQAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTATNGRYIGRYQL
                     DSSYLNGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
BASE COUNT        11948 a         6307 c         7460 g        10397 t
ORIGIN      
        1 gtggtgtagc cgcagaatcc caaactccag ctaaaccggc tgctgaaccc actgttgata
       61 cagaatcagc tggatcgtca agcgaaggag tcttccaatt taagttaccg gatatcggtg
      121 aaggaatcgc agaaggtgaa atcgtcaaat ggttcgtcaa accaggagat acgatcaatg
      181 aagatgatac attactagaa gttcaaaatg acaaatcagt agaagaaatt ccgtcacctg
      241 tcacagggac agttaaaaac gtgattgttc cagaaggcac tgtagcaaat gttggggatg
      301 tattagtaga aatcgatgct cctggacaca atagtgcacc gtcaactagt gcgccatcag
      361 ctgaagcacc aaaagaaaaa gtggaaacat caggttcagc aagtgtcgtt gaagctgccg
      421 atccaaataa acgtgtattg gctatgccat ctgttcgtca atttgcccgt gaaaaagatg
      481 tagatatctc acaagtaact gcaactggaa aaggtggcag agtaacaaaa gaggacatcg
      541 aaaacttctt ggcaggtggt ccaagcagtg cgccagcgaa atcagaagcg ccagaagcgg
      601 cagcaccgaa agaagcagct cctgcagcag aaagcaaacc agctgcacca gcaaaaccat
      661 tcaagtccaa cttaggagac ttggaagaac gtgtagcaat gacgccaaca cgtaaagcta
      721 tcgctaaagc aatggtcaac agtaagcata cagctccaca cgtgacattg catgatgaag
      781 tagaagtgtc taaactatgg gataatcgga aacgatttaa agaagttgct gctgcaaatg
      841 gtacgaaact tactttcttg ccatatgtcg tgaaagcttt aacagcgact gttaagaaat
      901 acccagtatt gaatgcatct atcgacgatg caaaccaaga aatcgtttat aaacattact
      961 acaatatcgg tattgcaact gatacggatc acggactata tgtaccaaat gtgaaagatg
     1021 cagaccgcaa aggaatgttt gctattgcag acgaaatcaa tgagaaagca aaattagctc
     1081 atgacggcaa actatctgca gaagatatgc gcaatggaac aattacgatc agcaatatcg
     1141 gatctgtagg tggcggttgg tttacaccag tcatcaacta tccagaagta gctattttag
     1201 gtgtaggaac gattgcacaa caaccaatcg taaatgctga aggcgaaatc gttgtcggtc
     1261 gtgtgatgaa actgtcatta agtttcgatc accgtatcgt agatggagca actgcgcaac
     1321 aagcaatgaa taatatcaaa cgtcttttag ctgatccaga gctattaatg atggaaggat
     1381 gataaacaaa tggtagttgg agattttgct gtagaattag atacagttgt aattggtgcg
     1441 ggacctggtg gctatgtagc tgccatccgc gctgctgaaa tgggacaaaa agtagcaatc
     1501 attgaaagag agtatattgg cggtgtttgt ttgaatgtcg gctgtattcc ttcaaaagca
     1561 ctgatagctg caggacacca ttatcaagag tcactagatt ctgaaatgtt tggagtaact
     1621 agtgaaaacg tcaaactaga ttttgcaaaa acacaagaat ggaaagaaaa caaagttgtc
     1681 catacgttga cttctggtgt tggtttccta ttaaaaaaac ataaggttga aacaatcgaa
     1741 ggagaagcgt tcttcgtaga tgatcacaca ctacgcgtca ttcatccaga ttcagctcaa
     1801 acttattcgt tcaataacgc aatcatcgca acaggttccc gtccaatcga gattccagga
     1861 tttaaattcg gaggacgtgt gttagattct actggcggat tagcattgaa agaagtacct
     1921 aagaaatttg tgatcatcgg tggcggtgtg attggtgccg aattgggcgg agcgtacgca
     1981 aacttaggag cagaagtaac gattcttgaa ggctcaccac aaattttacc aacttacgaa
     2041 aaagatctag taaaattagt agaagatgat ttcaagaaaa aaggcgtaac agtcgtaacg
     2101 aatgcaatgg cgaaagaagc agtcgataac ggtgacagcg tgacagtgaa atatgcagtg
     2161 gacgggaaag aagaatccgt tactgctgat tatgtgatgg tcactgtagg tcgtcgtccg
     2221 aatacagatg atatgggctt agaacaagcg ggtgtcgaag taggagaacg aggattgatc
     2281 acggtggata aacaaggacg tacgaacgta cctaacatct atgccatcgg tgatatcgtt
     2341 ccaggggcgg cattagcaca caaagccagt tatgaagcaa aaatcgctgc tgaagcaatc
     2401 tctggcaaaa aagtagctgt agattataaa gcaatgccgg cagtagcctt cactgatcct
     2461 gaattggctt ctgtaggtat gacgatcaaa gaagcaaaag atgctggtat cgaagcaaaa
     2521 gcatataaat tcccattttc agggaacggt cgggcattat cgcttggtaa aacagaagga
     2581 ttcatccgtc tagttacgac gatcgaagat aacgtgctta ttggcgcgca aatcggtgga
     2641 gtcggcgcaa gtgatatggt ctctgaatta gctttagcaa tcgaatcagg aatgaatgct
     2701 gaagatatcg ccttgacgat tcatcctcat ccatctcttg gcgaaatcgt catggatgct
     2761 tcggaattag cattaggttt accaatccat atttgatttg aataatacag gcgaaacgca
     2821 actgaaaaat cagttgcgtt ttgtttttta gaattatcaa taatattatt atgtaaactt
     2881 aaaaatatga caacttcttg gtttattacc acttcctatg ctacactgaa gaggaatatg
     2941 aaataggaga gttgaagatg caagaatatc agtatccact tgatttagat tggacaacag
     3001 acgaaatggt cattgtaatg aagatgtggg aagatctgga acgtgcgaat gaaaaaggga
     3061 taaacaatga agcttttttg aagacttatc agcagtttaa aactgttgtc aaatccattg
     3121 gtgaggaaaa acgattggga cgggaatttg aaaaagcttc cggttattct ttatatcgta
     3181 cagtgcagca agcaaaaaaa aatccaaaca aaactttgag aatgaacggg tgagataaat
     3241 ggaacagatg attgatcata tcaagtcctg gcttgaagaa gctggtgaga aaatcaaatc
     3301 ttctcaacaa acattaacaa tctcgcaaaa atcaaatcga acggatctag taacaaatgt
     3361 cgatcgaaac atccagaatt ttctaatcga aaaaatccat tcctttgatc cagaggcgaa
     3421 aatattggca gaagaagaag ggtgtaatca attatcggat ctcgatggaa gagtctttat
     3481 catcgatcct attgatggca ccttgaattt tgtgattgaa ggggaaaatt tttgtattat
     3541 gctcgctgtt tatgaatccg gcgttggaaa gcttggtttc atttatgacg tgatgagaaa
     3601 tgaacttttt tggggtggaa aaggaatagg cgtgtataaa aatgatgagc cattgcctag
     3661 accagcaaat aaatccttat cggaaggctt acttggtgtg aatagttatc ttttcggtca
     3721 taataaatat ggaatccgag aaattgcgga aagcagcatg gggacacgta tgtacggatg
     3781 cgctggtctt gaactagtgg caatcttgaa aggaaaccac attgcttata tttcaaacct
     3841 tagcccttgg gattatgcag cgggaaatgt cttattggaa gagtttggta tggtaacaag
     3901 cggtcttttt ggtactcctt tgacatttga aaaaagggaa tactatttag cagggacttc
     3961 ttgtgcatat gcagaaatcg cagacctttt gaaaaaagaa ggctgaaaaa aaggtagaaa
     4021 tcattcacaa aaatgataaa aacgagcaaa agattaattt tctcgaaaaa atgaaaacat
     4081 tttactatat ttcatgaaaa aagtctgcta taattagcag tcgagtaaaa tttgccctgt
     4141 cataaagaac caataaaaaa ggagttagtt acattgaatt atagaaacga tatccgtaac
     4201 gtcgcaatta ttgcccacgt tgaccacgga aaaacaacat tagttgatga actattaaaa
     4261 caatcagata cattagacgc acatacgcaa ttgcaagaac gtgcgatgga ctcaaatgcg
     4321 ctagaaaaag aacgtggtat cacgatttta gccaaaaaca cagctgtaga ctataaaggt
     4381 attcgcgtaa acatcatgga tactccagga cacgcggact tcggtggcga agtagaacgg
     4441 atcatgaaaa tggttgacgg cgttgtgttg gtcgtagatg cgtatgaagg aacaatgcct
     4501 caaacacgtt ttgtattgaa aaaagcactg gaacaacata tcacaccaat cgttgtcgta
     4561 aacaagattg acaaaccttc tgctcgtcct gagcatgtcg tagatgaagt tcttgaacta
     4621 ttcatcgaat taggagcaga tgatgatcag ttagactttc ctgtgattta tgcatctgca
     4681 ctaaatggta cgtcaagctt gtcagatgat ccagcagatc aagaaccaac catggcacct
     4741 atttttgata caattattga aaaaatccct gctcctgtcg ataacagcga cgaaccatta
     4801 caattccaag tttcattact tgactacaac gattatgtag gtcgtatcgg aatcggacgt
     4861 gtatttagag gaacaatcaa agtaggagac caagtagcat taattaaatt agacggaaca
     4921 gttaagaaat tccgtgtaac gaaattattt ggtttctttg gactaaaacg tctagagatt
     4981 caagaagcaa aagctggaga cttgattgct gtctcaggta tggaagatat ctttgtcggt
     5041 gaaacagtta ctcctgtgga tcatcaagat gcgttaccta tccttcacat tgacgaacca
     5101 acattgcaaa tgactttctt agttaataat tcaccatttg ccggtcgaga aggtaaattc
     5161 gtaaccgctc gtaagattga agaacgtttg atggcagaac ttcaaacaga tgtatcctta
     5221 cgagttgaac caacaaactc tccagatgca tggacagttt ctggtcgtgg agaattgcat
     5281 ttgtctatct tgattgaaaa catgcgccgt gagggatacg aattgcaagt atctcgtcca
     5341 gaagttattg aaaaagaaat cgacggtgta aaatgcgaac cgtttgaacg cgtgcaaatc
     5401 gatacaccag aagaatatat gggtagtgtt atcgagtcct tgagcttacg taaaggtgaa
     5461 atgcaagata tggtccatac aggaaacgga caaatccgtt tgacattctt aacacctgcc
     5521 cgcggtttga ttggttattc aactgaattc ctttcaatga cacgtggtta cggaatcatg
     5581 aaccatactt ttgaccaata tctgccaatg cttcctggtc aaattggcgg acgtcaccaa
     5641 ggggcgcttg tttcgatcga tacaggaaaa gcaacgactt attctatcat gagtatcgaa
     5701 gaacgcggta cagtcttcgt agaaccaggt acagaagtat atgaaggaat gattatcggg
     5761 gaaaacagcc gtgataatga tttgactgtc aacatcacga aagcaaaaca aatgacaaac
     5821 gtacggtctg ctactaaaga ccaaacatct gtcatcaaaa aaccaaaaca attgacgttg
     5881 gaagaatctt tggaattctt gaatgatgat gaatattgcg aagtaacacc agaaagcatt
     5941 cgcttgagaa aacaaatttt agagaaaaat gctcgtgaaa aagcatctaa aaagaaaaaa
     6001 taatctgtaa aaggatgaag agagaaacca gcttgttata aaaaatagct ggtttctttt
     6061 tttgtccaac tcttttctgt ggagaagtca tctttgtcaa tggacataaa ttcagaaaat
     6121 acgccgaaag acgtttaaaa gacttttaaa aaacttattt ctagagagtt tttgtttcat
     6181 aataagataa tgtttcacga aaggagatca acttgtcctt cgaagaaaat cgaagtaaaa
     6241 tggcaagaga aaggagcggg aagatgaacg acttattaaa acaatacttt ggctatgatg
     6301 agtttagacc tggtcaaaaa gaaattatcc agaaagtcat tgatcaggaa aatgtattag
     6361 gaatcatgcc taccggaagt gggaaatcaa tctgttacca gcttccagct ttactattag
     6421 atgggcttac tgtggttgtg tcccctttaa tctctttgat gaaggatcag gtggacgcgg
     6481 cgaatcaatt aggtataccc gccactttta tcaatagctc gttagatggt tacgaaacag
     6541 ctagacgctt ccaagaaatc gatagacagc agtaccgttt actttatatc gctcctgaac
     6601 gttttatcat gccggatttt atccaagcaa tgaagcgatg gaacgtccgt atgatcgcta
     6661 ttgacgaggc acattgtatc tctcagtggg ggcatgattt ccgcccaagt tatttacaga
     6721 tggcgaacca gctagatcaa ctgccaaatc gtcctgtaat tgttgctttg acagctacag
     6781 cgactgtgca agtagctgct gacataaaaa gacttttaaa aattccagaa aacaaccata
     6841 ttcagactgg ttttgaacga gaaaatctac gatttcaagt aattaaagat caaaaaaaag
     6901 aacaatatct aatcgaatat ttaaagatca acaaaaatca atctggtatc atttatgcag
     6961 caacgagaaa agaagtagac cgtctctatc atttgcttaa aaaattcgat ttttccgtgg
     7021 gtagatatca tggtggtcta aatgagaatg agcgaacaga aatgcaagaa gcctttttat
     7081 acgatcgctt gcagctgatt gtagcgacaa atgcatttgg tatgggtata aataaaagca
     7141 atgtccgttt tgttatccat tatcaaattc ctggctctct agaagcatac tatcaggaag
     7201 ctggtcgggc gggaagagat ggtctttcca gtgaagccat cctgcttttc tctcctcaag
     7261 atatccaagt ccaaaagttt tttatccagc agtcccaaag agaagaaggg caaaagcaaa
     7321 aagaatatga aaaattaaaa gcgatgacag aatacgtgta tattgagtcc tgtcttcagc
     7381 aatacatcct aaactatttt ggcgagacaa gcagtccgtg caaccgttgt ggtaactgtt
     7441 tagatgacag agaaatagta gaagtaacga cagaagcaca gatggttctt tcttgcttaa
     7501 aacgtatggg tgagaactat ggtaaacaaa tgctgatgaa agtcttagca ggatcgaaag
     7561 aacaaaagct gcaagcttta ggttttggac atttatctac ctatggactg atgaaaaacc
     7621 aatcgcaaaa agaaacgatg cagttaattg aatatttgat atcgaatggc tatcttctga
     7681 ccatcaatgg tgagtatcct gttttgaaag taacagaaag agggatacaa gtattgaaag
     7741 gacaagaatc tgtttatcga aaggaaccca agaaagtcca gcagctatcg gatgaagaaa
     7801 ccgatacact atttgaagtg ctgcgggaac tgcgaacgga tctagcatca gaagcaggcg
     7861 ttcccccgta tgtcgtattt tcagattcca cattgaaaga aatgagccga atacgtccat
     7921 caagcagatt ggagatgctt cagataaaag gagttggcca aagcaagctt gataaatatg
     7981 gcgaagcctt tttatctcgg ataaaaaatg cggactctaa cgttctggat aagtagaaag
     8041 aacgaatacg taaaaatgaa taaaaacaac tggttaaatc tgtttttttt gctccttatg
     8101 aaaatcaaat atgttataat taaggaatta gaatgggagg taagcacaga tggattcttt
     8161 gtcgaaaaaa cttgcgatcc aagtattaaa tgatgaagca gaacggatca aacgattaat
     8221 ccgaaatcaa aacaacagtc tctgtatctc acaatgcaaa gccttcgaag aagtggtaga
     8281 tacacagatg tacggctttt cccggcaagt cggttttgct gtccgtatag gagtaatcgg
     8341 aaagaacgag ggccagctga tgttaagtga gctagaacga gaattgaatc agttatatag
     8401 tgaggtttac caagaaattt atgataaaaa agaagttggc aaggaggaat agacttgcct
     8461 aagaaagtga aaaaaaggca tctattagac tatagcatct tgattcccta tttaatttta
     8521 tgtgtattgg gattgatcat ggtatatagt tctacgtcgt atctattatt agaaaacgga
     8581 caaaatccgt ccgcatcagt cattaaccag agtatttttt gggtgcttag cttgattgct
     8641 atcgcactac tttataaaat gaaaacagat gttttgaaaa accagcgttt gatcatggca
     8701 gccatcgcag ttttgacgat tttgctgctg attgttgtgt tttttggtaa ggagatcaat
     8761 ggggcgaaag gttggctgca aattgcagga ttctcgatcc aacctgccga atacctaaaa
     8821 atcatttcta tctggtacct gtctctgact ttatctaaaa gacaaaacag tgtacaaaaa
     8881 gattttcttg ggactgtgaa acgtccactt gcaatggtta tcggacttac tgcattagtc
     8941 gctattcttc ccgattttgg taatgcggca gttatctttt tgattatttt ggttctgctt
     9001 ttagccagcg gagtcaatta tgtgtatact ttgattgtag gagtaggagg cttttgtcta
     9061 agtactttta cgatctggct gatcaatatc acaaacggaa agatcttacc cggacgttta
     9121 cagtatatct ataatcgatt tgctatttac caaaatcctt tctcagacga attaaataaa
     9181 gggcatcaac tagtcaacgg ctactatgcc atgttcaacg gaggactatt tggcagggga
     9241 ttaggtaaca gtatccagaa aaaaggattt ttacaagaag cacaaaccga ttttatttat
     9301 gcaatcgtag tggaagaact gggagtgatt atggggattt tgatattagc gttgctattc
     9361 tttatgattg tgcgcattgt ccttgtaggt atccgttcaa aagatccgtt caattcgctt
     9421 ttgtgcattg ggatcggcgc aatgtttttg atccaagtat ttgtcaatct tggaggaatt
     9481 actggcgtta ttcctttgac agggatcacg ttcccatttt taagtcaagg aggctccagt
     9541 ttgctgatgc tttcgatttg tgtcggcttt gtcctcaaca tcagtgcgga tgaaaaacgc
     9601 aagagcttag gtttataata aaaaaagatg taggagtggt tcgatgaaaa aagttttagt
     9661 tgctaacagg ggtgaaatcg ctgtacgtgt atttcgtgct tgtacagaat taggaattaa
     9721 aactgttgga atctatgcag aagaagatga atattccgta caccgtttca aagcggatga
     9781 agcatattta gtaggacaag gaaaaaaacc gattgatgcg tatctagata ttgaagggat
     9841 catttctatc gcgaaagaat gcggagctga cgctattcat ccgggttacg gtcttttgtc
     9901 ggaaaacttg aattttgcgc aacggtgcga agaagaaggc atcatttttg ttggacccaa
     9961 actgcatcat ttagatattt ttggagataa aatcaaagca aaagctgcag ctatcgaagc
    10021 ggggattgct tcgattccag gcacagatgg accaatcgct tctatagacg atgccttgga
    10081 gtttgcgaaa caatacggtt atccgattat gatcaaggca gctctaggcg gcggcggacg
    10141 cggcatgcgt gtagctcacg atgaaaagag tgcaagagag ggctacgaac gtgcgaaaag
    10201 cgaagcaaaa gcagcctttg gtagtgatga agtgtatgtt gaaaaataca tcgctaatcc
    10261 taagcatatc gaagtacaga ttctcgggga tacgcatgga aacgtcatcc atctttttga
    10321 aagagattgt tctgttcagc gccgtcacca aaaagtagta gaagtagcgc cttgtgtctc
    10381 tatgaatgaa cagcaacgtc aaaaaatctg ccaggcagct gtccaattga tgaaatatgt
    10441 cgggtatgtc aacgcaggta cagtagaatt tcttgttgaa ggagatgatt tttactttat
    10501 cgaagtcaac cctcgcgtcc aagtggaaca tacgatcaca gaaatgatta cagatattga
    10561 tatcgtaaca acgcaactgt tgattgctca aggtttggat ctgcataaag aaatcggatt
    10621 gcctcagcaa gaaggaatta aattaaatgg ttcagccatt caatgccgaa tcactacaga
    10681 agacccgttg aataactttt taccagacac agggaaaatc gatacgtatc gttcacctgg
    10741 tggttttggc gtacgtctgg atgtcggaaa tgcttacgcg ggctatgtag tgacaccgta
    10801 ttttgattca ttgctagtaa aagtatgtac gcatggtgct acctttgaaa cagccattca
    10861 gaaaatggaa cgttgcttga aagaatttag aatccgtgga gtgaaaacaa acattccatt
    10921 tatgctcaat gtcatcacac atcctgaatt ccaatcagga aatgcaaaaa caaccttcat
    10981 tgatagtaca gcaacattat ttgaatttcc tcgactacga gaccgcggaa acaaaacgat
    11041 gaaatatatc ggtgaaatta ctgtgaatgg ttttccaggt atcgaaagtg gcgaaaaacc
    11101 attttatgaa gaaccacgta tgcctaaaga tctaatcaca agaactgatt acgtaacggc
    11161 taagaatgta ttagatgcga agggtgccga tgctttggtc gaatggatca aaggacagga
    11221 aaatttgttg ttgacggata cgacatttag agacgcccat caaagtctgc tagcaactcg
    11281 tgttcggaca aaggatttca agcagattgc acgtttgact ggagaaggtc ttcctgaact
    11341 cttttcaagt gagatgtggg ggggagcaac atttgatgtg gcttaccgct ttttgaatga
    11401 agatccttgg caacggttga gaaaaattcg ttctttaatg cctaatacgt tgctgcaaat
    11461 gcttttcaga ggttcaaatg ccgttgggta ttctaattat cctgacaatg tattggtgga
    11521 atttgtcaaa gaagcagcag cgcaaggaat cgatgtattt cgaatctttg atagtttgaa
    11581 ctggactcca caaatggaaa aaagtatcca agctgtacgg gatactggta aaatcgcaga
    11641 ggcagctatt tgctatactg gcgatatcaa cgatccaagt cgggcaaaat acaatgttca
    11701 gtattataaa gacatggcaa aggaactaga acaactgggt gcgcatatca ttgcaatcaa
    11761 agatatggct gggctgctta aaccgcaggc agcttatcgt ttgattagtg aattgaaaga
    11821 aacgacagat ctgccaatcc atctgcatac tcatgatacc agcgggaatg gaatcatcac
    11881 ttattctgct gcttcaaaag caggagtaga catcgttgac gtggcaatga gtgcaatgag
    11941 tgggaatact agtcagccta gcatgagcag cttgtattat gcactggtca atggtccacg
    12001 gctgccagaa atcacgattg aaaatgcaca gaaattaaac cattattggg aagatgtgcg
    12061 catgtattac aaaccgtttg aaaacggctt gaatgctcct gaaacagaag tatatatgca
    12121 tgaaatgcca ggaggacagt attcgaatct acagcaacag gcaaaagctg tcggattagg
    12181 tcatcgctgg gatgaaatca aacaaatgta tcatactgtc aacttgatgt ttggcgatat
    12241 cgttaaagta actccatcat ctaaagtagt tggagatatg gcactattta tggtccaaaa
    12301 tgatcttaca gaagaagata tttatgaaaa aggcgaaaca ctaagtttcc ctgaatctgt
    12361 tgtgactttc ttccaaggag aactagggca acccgttggc ggatttccta aaaaattgca
    12421 aaagattatt cttaaaggca gacctgcatt gaatgaacgt ccaggtcttt tggctgaatc
    12481 agtcgacttc aacgaagtaa aaaaagaatt ggcagaaaaa attggctatg aaccaaaaca
    12541 agacgaagta ttaagctatt tgatgtatcc gcaagtcttt ttggactatc aaaaagcata
    12601 taatcaattt ggcgatgtta cattactgga cacaccaaca tttttccaag gtatacgttt
    12661 gggtgaaaca atcaatgtac aaatcgaacg cggaaaaacg cttatcattc gtttagatga
    12721 aatcggagaa cccgatatcg aagggaatcg cgtactgttc ttcaatttga atggacaaag
    12781 acgtgaaatc actatcaaag ataattcgat catcagtacg gtccaaaccc gattgaaagc
    12841 tgaaccgaca aaccgagaac aaattggagc aacgatgtct ggttctgttt tggatgtatt
    12901 agtgaaaaaa ggcgataacg ttaaaaaagg tgatacgttg atgattactg aagcgatgaa
    12961 aatggaaacg gccatcgaag cacgttttga cggagaagtc gcacatgtat atgtgtcttc
    13021 aggagacact atttcgtctg gtgacctttt gattgaagtg actgagaaat aataagcgaa
    13081 aggtggggaa acatgaaaag actgggtttg ttttggctga ttctgctatt agttattgtg
    13141 gcattctaca tggaaccagt cttgtttccg ccaaaacttg aagtgaagga aaactctgat
    13201 caacaaatat caaaccaaat gacaacgtgg aaataccagg agcttaaagc aactggtttt
    13261 tctacttata tcggaaaacc gatcgatcag ctggaaaagg attttggcca agcctatgat
    13321 cgattaacta gcggatttgg ttttgaaaca agatattatg aaaataaagc tagtcatctc
    13381 acatttgaag cgaacatcca agacagcaga gtcacaactg ttaaagtact gcaaacaggg
    13441 cctgctgata tcgcgccgtt ttatttaggg atgacgatgc aagatcttac gaaaatcact
    13501 actatctata ctaatttcac ttttgagtac catgatacag aagttggaat cgaactaatg
    13561 gaagaggata tgaattatcg tccgctaatt gcttttgata acgacacttt tgctatttta
    13621 ttttttgatc aaacaacaaa cggcctattt tcagttgtgt atttagataa agatagtctt
    13681 ttgaaactat tgccatatca agtgtttggt gaaggccttc cacattatca agcagataaa
    13741 tcggctgatt gggaatcaat caatcgcgtt aaagaacgaa aaagtacgac tttattaaat
    13801 atgcttagaa gagaagacga acttcccata tacaatcaaa cacttgcctt tcaaaaccac
    13861 agtcagctgc tactacatga ttttttgaca aggcctgagg aaatattgtc agaggaacgt
    13921 atggctgatt ggcaaaaatc gctaggcagt gctcaaacga cagtgaaatt ctcactgacg
    13981 aatgatgaat tggagaagtt aatcagtaaa caaaaattag aaaatactag tgggctattt
    14041 attcatccgg cgattgacgc tactttttcg tttttatatt ggtacagcga tccttacaac
    14101 catgaccgtt tcatggaccc gggaacggat tctgtaggca ttgctttttc taaagaaaat
    14161 atgttagtct tattgcaaga agaaaacgga gaaagtagtg atagcagtga tcgttaacga
    14221 agagctgttt caactggagg atcaatgcct ccaagtcgct gaaatgataa aaaagagtaa
    14281 aacgatggct tcttatcttg aacataaaca gtcaatggaa gaatctgcaa aagtttgcca
    14341 gttgaaagaa gcgttcttgt ctaagaaaga agcatttgaa aatgtagcgg catatggtga
    14401 gtatgcacct gattatcgtg aaaaaaaacg agctgttcga aaagcaaaaa gacagcttga
    14461 tatggatgag catgttgcag ctttccgata tagtgaaaca cagctgcaaa gtctgttgga
    14521 tcaaattgtc caagtacttg ccgaagaagt ttctaatgaa atcaaagtag atgcaggtag
    14581 cccgtttttt gaaacgaaaa aacactttgg atgcggaggt aattgtcatg caattagaca
    14641 atagtgaatt tgaaataaca aaacgacgcg ggctgatcgt atgggtctac agcttaaaac
    14701 aattaaagaa tctgaaaaag ttcggcttgt tgcattatgt ctcaagaaga atgaaatatg
    14761 tcgtgcttta cttaaatgaa gagacattgg aagaaacaga agaacgaatc cgtaaattac
    14821 attttgttcg aaacgtagaa cgttcttacc gaccggatat cgaaatgaat tttgccgaaa
    14881 aaataggaaa caaaacagta ttaaaagacg aaggtttcga aattgaagag ctaaatacag
    14941 aaatccgatt agctgaacat ctttaaaaat ctcttatgag cagtttttaa ataaaaaata
    15001 acttggataa cgatcgattt ttgatcattg tccaagtatt tttttggtat actagtacca
    15061 gtaccatttc taaggagtga gtagatgcgg ataatatcag gaaattatgg cgggcgccgt
    15121 ttaaaaagtt tagcaggggc gaacaccaga ccaactacag ataaagtaaa agaatccata
    15181 ttcaatatga ttggaccata ttttgatgga gagacagtat tggatctgtt tgcaggaagc
    15241 ggtggtttag ctatcgaagc agtatctaga ggctgcagtc atgcggtatg cgtagacaaa
    15301 aattaccaag cgctaaaaat catcaaagaa aacatcgaaa ttacgaaaga accagagaaa
    15361 tttaccacaa taaaacttga tgcggacaaa gcaatcgaac ggctagcagc ggagaaacaa
    15421 caattcgact acttgtttct tgatccgcca tatgcaaaac aaaaaataat cgatcaaatc
    15481 cataaaatgg aagaactggg acttttttct aaaaccgcag ttatcgtatg cgaaacggat
    15541 aaaacagtcg aattgccaga aactgtggct ggattccatc aaataagaaa acagatttat
    15601 ggcataacgg ccgtaactat ctatagaaaa gagggaaatc aatgaaacgt gcattattcc
    15661 caggaagttt tgatcctttt acaaaaggtc acttagatac ggtggaacgt gcggctaaat
    15721 tattcgatga ggtagtaatt ggtgttttta tcaatacttc aaagaaaagt ttgtttcccc
    15781 cagaagaaag aatgacattg atcacaaaag ctgtttctca tcttcctaat gtaaaagtca
    15841 tgcatcaaga aaatcaattg acggtagaaa cagcaaaaga gattggtgca gatgcgttga
    15901 tcagaggcat acgaagtatc aaagactttg aatatgaacg agagattgct cagatgaatc
    15961 atcatctata tgatgaattg gaaactgtct tcttattagc aaaaccagaa tatagtcacg
    16021 tgagttccag tattttaaaa gaagtactgc actttggcgg agatgtgagc agctacttac
    16081 cgccagtgat caacgaagct ttagctggaa agcgtgaatc aaatgaaagc taaacaatgg
    16141 ttgaaaacag tactgattat catatttgga atgttgatca ttggatttgt agtagttccc
    16201 ttgccgtatt atgtagaatc accgggagcc acgatcgatc tgaaagaact aattacggtc
    16261 aatgataagg aagataaagg ttctgggtct ttctctctta cctctgttgg tatcaggcaa
    16321 gctacaggtt tcttagcttt aaaagctaaa atgacccctt ttgaagaatt gatcagtgaa
    16381 gaagaattga ctggtggggc gacaaatgaa gaatataatc aaatgcaaca gtattatatg
    16441 gattcttccc aaaatgcagc aatcgaacaa gcgttaaaac ttgcagacaa gccttataaa
    16501 atggaattca aaggcgtata tgtcatgagt gtagagaaaa catcgaattt ctttggcaag
    16561 ctttcagttg gagatacagt aacaaaagta gacgggaaaa gctttcaaag tacagaagca
    16621 tttatggatt atgtaaaaag ccaaaaagtt ggacaaacaa tcgaaatcag ttatttgcat
    16681 aatggtgaag aaaaaacagc ttctggtgat ctgatcgagt taccaacaga taaaaaggca
    16741 ggaataggta tcacgcttac tgaccatacc gagatcgaat cagatacaga tgttcgtatt
    16801 aattctggct ctatcggtgg gccatcagcg ggattgatgt tcactttaga aatctatgaa
    16861 caagtcactg gtaaaaactt gcgacatggt aagcaaattg caggaactgg aacgatcaac
    16921 agtgaaggag aagttggccg aatcggagga atcgataaaa aagtggcaag tgcggataaa
    16981 gctggcgtag agattttctt tgcaccagat gatacgattt cagacgatgt taagaaagaa
    17041 tatcctgaaa taaaaaccaa ctacgaagaa gcaaaagctg ccgctaaaaa attgaattcc
    17101 tcaatgaaaa tcgtaccagt aaaaacagta caagaagcgc ttgactatct agagaaaatg
    17161 aaatgaaact aaataattaa agaggggttg tgacacgagt tctgtcacaa cccctctttt
    17221 tcgtcaaaaa tcttcacgat aaaaataaaa acaaaagaaa aaattgacgt aattagatgt
    17281 tgaagggacg attttgccag agctcactgt ttcttcaatt ttaaatgaaa ggagtaatga
    17341 atgattttta ctggtcattc tttgaaaaaa gaacaatgat agaaaaaatc agcaagaaaa
    17401 tactagcttc acccaaattg atcatttgga tgtctatgat agttcttatc ttttgtatcg
    17461 caagtggttt tttattatca aatttgctat tttatagaga aacagaagag actgctgcaa
    17521 aagaaatact ttcttcgttt agttccagtg gagaagatcc atcagctgaa ggaaacgatg
    17581 tagaagagga tgctcgtcca aaggtcatgt acaccgatat caaaggaagt gtgaaggagc
    17641 ctggtatcta ttccttttct tcagaagaac gggtctatga tgtactaaag cgtgcaggtg
    17701 gattattaga agaagcggat agcgatcgaa tcaacttttc tgcgaagata gaagatcagc
    17761 aagtcctata tatccctgct gtaggtgaag agctgccaga acatcttgat cagttggcat
    17821 cctcggaagg aaaacagcct acagcagatt ccgagcctcc caaaataaat atcaatacag
    17881 ccactccatc agaacttcag cagattcctg ggatcggatc agtcaaagcg caagaaatca
    17941 ttcgatttag agaagaaaac ggatccttcc agaaagtgga agacctgcag gagatttctg
    18001 gtatcggtga aaagacagtt gaaaaactaa aaaacttcgt tacaattaaa tagaatgatt
    18061 caaaatcgac tggcacgagc aataaatgga cgctaatgga tactaagaat aatccaattc
    18121 taagagcttg gcaggacgag gaggtagtat ttttggatag gaaatagctt gattgttcgc
    18181 aaagaaacat taaaaaaacc aatgctgaat gtctatctcc aaaataaaat atctgggatt
    18241 catattatga atacggctgt cagcggcaat aacagtcaag ctctacgaga acgctttgcc
    18301 aaagatgtac ttagctatac agcagataaa gtatttattc tcattgggac gaatgatcta
    18361 gcagagcata aacaactttc taaagaaacg taccaaaaaa tctgcagtgg atgatagttc
    18421 agctgaaaaa agactatagt tctgatcatg ctttctttat cacgccacca gcagtcgatg
    18481 agacaaaaca aaaatatcgg aataacaagt tgatcaaaga atatatctct gttctcacag
    18541 aagtagcaaa acgccatgat tgtgaagtat cgatttttat acggaatttc ttgaacaaat
    18601 ggattcgaag aatttttata atgggctaat ggatgacgga cttcatttcg gcagtgaagg
    18661 gtaggatctt ttgtcagaca ggatgattcg ttatatttaa agaatatttt gtttaagcaa
    18721 tgagtacttt ttaatcaact tgaaaaaacg gaggaatata aaacatgtta gaaaaatctt
    18781 caaaagcatg cgatacgaat aaagaaaaag ttactgataa gtcacataat gaacgcattc
    18841 cttgggacca gtactttatg gctcaggcag tactgttatc tttacgtagt acgtgtacac
    18901 gtttagaagt aggagcgaca ctcgttcgag aaaaaaggat cattgctggc ggctataatg
    18961 gagcagtcag tggagatgtc cactgcatag atgaagggtg ttacgtcgtg gatggacact
    19021 gcttgcgaac gatccatgca gagatgaatg cactcctaca gtgtgcaaaa cttggtatcc
    19081 cgacggaagg ttcagaaatc tatgtcacac attttccatg tttggcctgt acaaaggctt
    19141 tgttgcaagc tggtgtgaaa gggatcaatt atctccatga ctatcgaaat gatccttatg
    19201 cccaagcgtt gatcgaacaa ttaggtgtat ctgtacacca agttgcttta gactcacagc
    19261 atttttcaaa acttcaaaat gaattaacag gaaaacatgt ctagcgtttt agaaaggcat
    19321 gttcgaaatc ggttgatttt tccggcaatt acgtcgatga ttatctgttt gttgtattac
    19381 actgacaatt ggggttatcg tttgcttctt gccggaattt ttttatggtt ttcgctaaaa
    19441 gaaggacgtt ttatcgcgta cttgtgtatt ttgtgtagca taacggtatc catttcttat
    19501 aggctacaag agtattcatt tttagaggaa aaaacaacat ctgcgcaaat tactgtattt
    19561 acagatacga ttcgtgcaaa tggtaatttt ttgacaatgg aaggaaggtt atcagagaat
    19621 aaacaaaagc tccagctttc ttatcaagta aacacagaag cagaattgaa aacatggctt
    19681 aacttccgag gaaagggaat agaattgact gctgaaggcg agttcatctc tccagcaaaa
    19741 aagcggaatc tttataattt tgaccaagaa gcttacttca ggaaccatag aatttctgga
    19801 cggttccaaa ttcaaaagat tgaacagatc accatgcaaa atcactggcg aaactggctt
    19861 cagagaaaaa gaggatcttt tatctccttt gtccaatctg aatttccgca aaaaacaagt
    19921 gtatatatta attctttatt atggggctat aaagatgcag gattcagaga accagaagaa
    19981 atttttaggg agagtggttt gctgcatctg ttcagtctat cgggtctaca catccaattt
    20041 tatttagggt ggctgtatta tttgtttcga cgtatcggat ggccactaca cgtcagtatt
    20101 attccgttga gtctactaac tatctgttat gtttctattg caggaagttc tatttctgtt
    20161 ttgcgtgcta gtttgctgtt tttattgcga ttgctagtca aattgctgaa taagcattat
    20221 tccaccatgg acttatttgc agttgtcttt tggcttcttt tactatttga tcctcgattt
    20281 ctttttcatg cgggtggaca gcttagtttt ttcatgagtt ttttgtttat cctgatttct
    20341 tttgatggag attggttgaa aaaaacggcc tctcacgtcc tgtttactat gatcacgatg
    20401 ccgttgattg tatggcattt ttatgagtgg cctattttag gtagtctttt tacattactg
    20461 attgcaccgg tattcaagtt tctttttctt cctggtgtgt tatttctcac actcttcaat
    20521 cgctggctgc cggaaacttt acttttgctg atagaagagg gattaatctt atttgagcga
    20581 ataatcgatt tttcttcagg gtcgtctctc attataggac gtttgcccct tgtgctatct
    20641 gggatgtata ttttcggatt actgatttgt atggataggt tgaaagaaca acctgtgaaa
    20701 cacttgtttt atgttggtct tttttctttt atttttttga ctttgccatt tttacgcttt
    20761 tcttcaacga tcgcttttat cgatgtcggt caaggagaca gtatcttttt gcaaagtcct
    20821 tttcgaaaag aaacgatttt gatcgatact ggaggtcagt tacactttga aagagaaaag
    20881 tgggcgcaag gtatgatacg tcctcctgct gaaagaaata tcgttccata tctaaaaggt
    20941 caggggataa gtgtaatcga taaactcatc ttgacacacg acgatacgga tcatgtggga
    21001 gaattaccca cgttatctca gcattttact atcaaaaaaa tttatatcgg ttggggcgct
    21061 ggacgaaatg agccattaca aaggcattta tctgaagctc aaaaaaatgg tactgagatc
    21121 attgaaatca aacatgggga caggatcagc ggttattatg atctttatgt attgactcct
    21181 tttgaaaagg gagagggaag aaatgaagat tcgattggtc tatggatgga atataacaat
    21241 aggcgctttt tatttttagg agatttgaat caagcaatgg aaaaacaatt gcttttgatt
    21301 tatcctaatc tgaaagccga tgtagtcaaa ttaggtcatc acggtagccg tacgtcaagt
    21361 aacacagatt ttctttccca tattgaagca aaacatggga ttatatcctg cggcgtaaat
    21421 aatcgttatg gtcacccgca cagcgaagta ttggagacac tagaagaaaa tcagataaaa
    21481 acatggcgaa cggatcaaca aggaatgatc acctatcgct ggcatccagt ttttcatcct
    21541 catgggctag tggaaacaat gatagactag taattctcat ctgctcatgg taggataatt
    21601 tttgaaagtg gtgagtaatt tgagtataca agcagagtta caaaaaatac gtaaagaaaa
    21661 acttgcatct tgttacttga ttttaggaac agaaaagttt ctccaagatc aagttcggac
    21721 agaaattgtc aaaaaaatcc aattagaggg cgaagatgac ttaaattttt taagttttga
    21781 catggaaaat gcaagtttag atgaggtagt agctgaagca gagacgttgc cgtttttcgg
    21841 agatcaacgg ttagtattcg tagagaatcc ttatttttta acaggtgaaa aagtaaacaa
    21901 tggaatcgaa caaaatactg atttattgac ggcttatttg aaagaaccat tagaatcgac
    21961 tgtattagta ttctttgcgc catatgaaaa gttggatgaa cggaaaaaag taacgaaaca
    22021 attgaaaaaa acagcaatta tcatcaatgt ccaacagttg aatgaaaaag aagtacgtca
    22081 atatctgatg aataccttag agaattcctc aatcaaaatg gaacgaagtg caattgattt
    22141 attcttgagg ttgaccgact tagatttatc caaaatgatg agagagttac agaaattggt
    22201 cctttatgga caaaatcaac agcaaatcac ggtaagagaa gtagaagaat tagttcctaa
    22261 aacgttagaa cataatattt ttgacatgac ccaatatatt ttaaaaggga agacggaaca
    22321 agctttgcgt ttatacgaag atttagttat gcaaggggaa gaaacaatca aaattaatgc
    22381 gattttgctt tctcaattac gtttattttt acagacaaaa tttcttgtaa agattggtta
    22441 tcagcaggca aatattgctg aaacattgaa aatccatcca tatcgtgtaa aacttgccat
    22501 gcaggaagta aaaaaattcg atgaacattt gctggtacag ttgtttgatc aattagttga
    22561 gatggattat caaatcaaaa cgggacaaat cgaaaaagaa ttaagttttc aactattcgt
    22621 tttgcgcaca gggcagttgt taagaaatcg ataagaagaa agacgagggc aaagcatgcg
    22681 ggaaggtcgt ttgtttttgt cctttttttg acaaataaaa aaatcggccg aagccgattc
    22741 ttttatttag cgattttttt gcttaaacga gatttgtcgc ggttagcttt gtttttgtgg
    22801 attagacctt ttgattcagc catatcaata gctttaacag cttctttata taacgcatct
    22861 acgttgtcag cacctgaagc tacagcatct tcaaattttt tgattgcagt acgcatagcg
    22921 cttgtttgag atgaattttt cacattagcg ttttcgcttg tacgaacacg tttgattgca
    22981 gattcaatgt ttggcattag tttcacctcc gataacttaa gttcttacgc gtgttaccgc
    23041 ataattcaac attcattatt atacctaaag gcagcgtgct ttgcaatatg aacatgacaa
    23101 gtttttttcc ttaacagtct tttattagga ttttttttca gtaaaaacgg atagtacaag
    23161 ctgaaaaaaa tcaaaaagac gctattgtgg gaggcaatag cgtcaaacca aactagattt
    23221 ttatttatct atttaaacaa agtttgaatg ggaatgtttg gtactaagtt attatataac
    23281 aaagagaacc gtttgcaaag ttttttttga aaagggatac gattccctgt tgttctttgt
    23341 ttttctatta agaaactgca gttattttat aaccagtatc ctttgatcag taaaggctat
    23401 tctggtgtac cgattatttt aatgtattca tcgatatttt ttatcaacat tttttttatg
    23461 accaactggt tccgacggtt ccatttgcca cttacttcca gcacatattt atttaggggc
    23521 aaacgtaaga tatattttgc caaatagcga tctttaagca ggccattgat cacacggtcc
    23581 tcaagctgca agttgatccc agtcagcatc attggctgtt cttgtaaaac gtacgtatca
    23641 attaaaagac cttcaaaagt ttccacaagc gtcttccttt cttttcaaag taacctgaaa
    23701 acaggcacta attcttccat tttgatattc gttgaagtgg atgcgatcat tctttctttt
    23761 gtccactgta atctagtata acaaaaaaga gcagaagagc caaaaagaaa aaagagcatc
    23821 gaattctata ggaagtctca ttggcacggc ctaaattatt acaaaacatt gattaaaaaa
    23881 agcccctgca tcgcaggagc atcccctata tcgttttaat aggtcaatca aaaagcagta
    23941 tcaaacacat tttgtatcaa atcaggaaat aatagataag ctaagcccag aatcaaaagt
    24001 accgctagaa gaaaccagcc gattgttcct atgaaatact ttaatttttc gaacattgta
    24061 tcacctcgtt gtcagtatat cacggatcag taaattgggg gtgttaagaa tctcctaaaa
    24121 tagacaaaat ttgttctatt ttcctaaagc aaatacttgt aagatacagt aagtgatacc
    24181 agaagcaatg accggtccgg cggcgattcc tcttaagaag acaacaccta aaatcgtgcc
    24241 gaaaacaagt gcaacagtga tttgtggatc agaagcaatc aatcctacac ccttggaaga
    24301 taagacagcc actagcccac cgcaaaaaac agctacccag ccaatagggg atttaaaggc
    24361 ttctaataga tcacgtagac cgatttctcc tgttgcgata gggattagaa tagccgctgt
    24421 gatgatcgtc accccaatat tgattccttt gccttgaagc caagggaaaa aggaacggga
    24481 ggctggtatg agcttcataa tcaaaacaaa agctgccgct atcatcagac tttgattttt
    24541 agctaaaatt gctacaagta aaataattcc taaaaaaagc caactttcca tgaaatatat
    24601 tcctcacttt cttcgaaaca atcataacat gtttttagaa agttacaaaa gtaggaattc
    24661 atccttcaag acctattcat aagctgtttt tttcataaaa taaacaaaat cataaaaaaa
    24721 cactttgctt atttgacaga agacagccgc gctttgtata gtggacaaga cttacatttt
    24781 tttgaagaat cagaaagatc aggtaaaggt cttagtaaac gcaagccatt cagaataacc
    24841 aatattgtgc ttccttcgtg tcctacaact ccaagaggta gatttaaaaa ttgcaggaag
    24901 ttagaagcaa tcaacaagag aataacaaga atcgaaaaaa taatattttg tttgatgatc
    24961 cgccgcattt ttaaagatag ccgatgactg tagacaaatt tatttaagtc gcttttcatt
    25021 aagacgatgt ctgcgatatc catagcggca tctgtccctt gccccatagc gacacctaaa
    25081 gaagcggctg ctaaagcagg cgcatcattg actccatcac caaccatcgc atttacttgg
    25141 taaagttcat tctctttttt gactagttgt gttttttctt ccggagtaca gcttgcatag
    25201 taatgttcaa tccctacttg ttcagcaatg gcctttgctg tgccagaatg gtcgccggtt
    25261 atcatacttg tatggatgtt ttgggattta aagtaggaaa ttacttgttg ggtatttgct
    25321 tttggaatat ctagcagacc taaaacagca attaactgct gatctttaga aagataaatc
    25381 acggttttgc cttgattttc caaacgttcg atcatttccg caatctcttt gctgattatc
    25441 atcgtctcag gatcatatgc gtgcttgcca actttccatt gcgcacctaa ataggtagtt
    25501 tgtaatccaa aaccagtaat ttcttctatt ggtaagtatt ggatttcttc aggtattgtg
    25561 caatcgaaat attgcaaaat cgcatgagca agtggatgcg tcgttttttg ttccatagca
    25621 acaagaagtt gttgtgccaa atccttttca tcaaagaaaa agctgtcagt tacaactggt
    25681 tttcctttag tgagcgttcc tgttttatca aaggcaatcg cttttaattc agaaagcttt
    25741 tctaaatgga taccgccttt gattaaaatc ccattttttg cagaatttga aagagcagct
    25801 agagaagctg gtgtagcaga tgcgacaagc gcacaaggag aagccacaac taataatacc
    25861 attcctcgat aaaagctttc atcccaactc caacctagga aaaagtgggg gagaaggatc
    25921 attagaggaa cagcaagcaa aatcaatttt acataattat tttcgattcg ttcgataaat
    25981 gaagctgttt gagttggcgt attctgcgct tcttctacta attggataat cttagcaaag
    26041 acagtttcgg aactcgtttt tgttactcga atcgtgatgg gatttccttg attcagcgtt
    26101 cctgcataca tctcatcgcc taaatatttt tctacaggca cagattcacc gcttaatgca
    26161 gactcatcga tcgttgcctg tgtgctttct aaaaagccat ctatcggaac agctgctcct
    26221 ttagcgacaa ataccaagtt atccaccttt agttgagaaa catctacttc ttgcatttgt
    26281 ccattttctt ttaataattg ggctttttgt ggttgaagat tcatcaaagc agtaatttct
    26341 ttttgacttt tattagttgt gtattcctct aatgcaccgc ttaaacaaaa gatgaatgtc
    26401 aacattgctc cttcaaagta attaccgatc aaacaggcac caatagcagc taaagccatc
    26461 aataaatcca cattcagtgt ccgatcattc cacaattctt tcaagccttc cgatgtttgt
    26521 ttatatccac cgatgataat ggcactgata taaaaaagtg gggtgatggt aagagagaat
    26581 cggtcgaaga taaaaccgaa gatcataaat aaaaggcagc cgattgttgc tgcaaaagct
    26641 tttttctgat tagtcatcgt tattagacct ccttgtcaaa acaaggatag cataataaaa
    26701 atgtaattga taataataac agctaaatga gaacgataat ggttatcatt tggtgattaa
    26761 gcttgatgtt gtttttatta tttataatga ttattattaa agaaaataaa aaaccagaac
    26821 atttctcaaa taagagaagt gttctggttt tttctacatt gcaataaacc aataaccaat
    26881 caaaatgata ccaaggataa tacgatacca gccaaaagcg gtaaagtcgt ttttcttcaa
    26941 atagcttagt aagaatttga tagctaagac ggaaaccaca aaagatacga atgttcctac
    27001 aagaagaaca acagtttctt ccattttgaa tgaattccct tcagctaaat atttgacgat
    27061 cttcaagccg cttgcgccaa acatgacagg aatccctaag aaaaatgaaa actctgtagc
    27121 gacaaaacgc gaagcaccaa tcaagataga tcctaggatc gttgcgccag aacgggatgt
    27181 tccgggaaca agtgccaaga cttggaataa cccaacaaga agagctgctt ggtacgtaaa
    27241 gtcattcaga gaagtccaac gaggtgtttt gtttttgttg cgtttttcga caataataaa
    27301 ggcaataccg taaacgatca aaacaatggc aactggtaag aacttgtgga aatttgcttc
    27361 taaccaatca tccaaaggca aaccaatgat gatggctggt atgcaagcaa cgatcacttt
    27421 aaaccaaagt gtccacgtat cttttttttc taccgttgat ttacttggag aaaatgggtt
    27481 taacttgtga aaataaagaa cgacgacagc caagatcgcc cctaattgga taacgacatt
    27541 gaacatcgac ataaattgtg aactggcatc cagtttgatg aattcatctg ctaggatcaa
    27601 atgaccagta ctactgatgg gcagccattc cgttattcct tcaataatac cgagaatcac
    27661 tgctttgata atatttgcaa aaaacataaa ttccttcctt cccaattaag atacatctta
    27721 tagtataccg ttattttttg agaaacccaa tctgtttttt aatattaaga aaaacttgag
    27781 aaataaagca gataagtaca cgaagagaaa aaagaagaca aagccctcgt tcagactttg
    27841 ccttttatga ttctctggta aaaattaaaa tatccccatt atagaaacga gtcgcgacta
    27901 tgtgttttcc cgttatcgat ataagacgta tcattgatgc cgtggataga aaatcgaccg
    27961 tttgcataag tgacctttgt tacgctgcca tttaaaagcc cagcacgaac aggctgttta
    28021 ggatcgatca gattaagcaa aaaggcgatc gtcaaaccat gagatacgac taaaacattt
    28081 ccaccaccat ttttttcgca gtgatgggcg atatcttcaa atcctgtcca tacacggtct
    28141 cgcaatgttt cataagtttc cgcccaccca gcggtatcta agttgtatac agcattagca
    28201 atttgttcaa aagaaacttc tgtggtaaac atttcatcat atgttttaaa attcaataca
    28261 cgagggatca caccccacat ttccatgtca tatccacctt caagagaccc gaaacaccat
    28321 tctctaatcc ttttttcaat aaaataagga atttcttttc ccttagaatg ttctcctaga
    28381 ataatacggg cagtttcgat tgcacgacca ctgtcactag aataagcaaa tgaaaagtcg
    28441 acatttttta acccgcgacc taaataatga atgccttctt gtccttgctt tgtgaggggt
    28501 gtatcacacc agccttgtac tcgttcaatt gtattgaaca tcgtttttcc gtgtcgtacg
    28561 atataaagtg tagtttctgt cattttattc tcctcctaag tcgttttaac gattgaaaaa
    28621 aggatttgtc cttttttcct gttcaatcgt cgttgcatcg ccatgtcctg gatagactgc
    28681 aaattcatca ggtaatacaa acagctgggt ccgaatacta tgaagtaatt gttctaaatt
    28741 ccctgtatac agatcggttc taccgatact tcctctaaac agggcgtcgc cagaaacgac
    28801 aaaatcatca aaaataaagc tgacgcttcc tatagaatgc cctggggtag ggacgacgcg
    28861 aaaagacatg tttcctaaag tataagtttt catttcaaat tcatattctg caggcgagac
    28921 aataacatca gcaatatcat catgtctacc gagtccagaa agattcaaaa tcggatcacc
    28981 tagccatttt tgctctagtg ggctgacata aactgggatt tgataatacg cgcgtaaagg
    29041 ttccactgca ccgatatgat cgtagtgagt atgggtaagc aaaatcgcta ccggctgttg
    29101 gtttgttttt ttgatttctt gtttgattcg ttccgcatct tctccagggt caatgatcaa
    29161 aagtgcttct tcgttgtaga ccaaataaca gttttcttca atcattcctg tttttaatct
    29221 ttcgatatgc atgtgcattc ctccttgata gccaaaactt ctttcatcca ttagtataac
    29281 gcattcattg ctaggaaaca aaaacaggta cttatttctc tttacttatc tgaattatca
    29341 gactatatga aaagtatttg gatattctaa agagaaggaa agtaagtttt catagcattt
    29401 taatatgtcc ttgttacatt agattcatcc aaaaatccaa attctatatc ctatatccct
    29461 gcctaatcag cagggtgttt ttttatgttt ggaaagagag ctctttttgc taaactaggt
    29521 tttttcaggt aatcttagag agaaagaggt ggtggaaatg atcaaacagt caaaaatatc
    29581 tgtgcggcac ttagtagaat ttattttgcg acgtggaagt atcgacaatc gtaaaaaaag
    29641 taaccatact gcattagaag gagcgagaat ccaccgcaag ctccaaaaag atgcgggaga
    29701 aaactatgaa aaagaagtct ttttaaaaac aacagttcaa ttagatgaat attacctgat
    29761 cgttgaaggc cgtgcagacg gtattttcaa aagagacggt atttattata tagatgaaat
    29821 caaaacctcc gaaccacgat ttgaagattt agaaccagaa caagtggaac ttttctttca
    29881 tcaagcaagg gtgtatgcct atatctatag tcaagaacat gatttacaag aaataaatct
    29941 gcaattgact tacttccaga cggcagaaga agtgatcacg agaaaggttg aacatcagac
    30001 aagagagcag ttagaaactt tttttaaaaa gctgactgaa gattataaag aatggcttgt
    30061 ttttcaagaa aactggcgca ctgtacgcaa tgcctctttg atggctttga aattccccca
    30121 tgatgagtat aggaaaggtc agcgtgaact agcggtagct gcttataaaa cgatccgtac
    30181 gaaacagaaa ttgtttgtag aagcacctac cggaacagga aaaacaatct ctacgttatt
    30241 ccccgctttg aaagctgtag gggaagaaga gggagaaaag atcttttatc taacggctaa
    30301 aacaataact agacaagtag ctgaagatgc tatgacagca ttaaaagata caggagctga
    30361 agtaaaaagt gtcactttga cggcgaaaga caagatctgc tttttagatg agacgacctg
    30421 taatccagat cagtgcccat atgccaatgg ttattacaat cggattaatg aaggtttatg
    30481 ggatcttttg aatcatgaga atcagatcac tcgtgaagtc atcgaaactt atgcaagaaa
    30541 gcatacactt tgtcctttcg aactatcatt agatgtcagt atctggtgtg acgtaatcat
    30601 tggggattac aattatttat ttgatccaac tgtttattta agacgttttt ttgaagatga
    30661 aaaaaacgag gactatctgt ttttgattga cgaagcacat aatttggtga atcgttcccg
    30721 agagatgtat tcggcagaac tatcttatga aaaaacgaaa cgaagtaagg aagctatacc
    30781 aaaggaattc aaaaaacttc atcgccgttt caacaaacta ttaaaagaat ttgattcgat
    30841 ccgagaaata gcaaaagaag atcattggga ttatcatcat caaaaagcac cggctgaatc
    30901 tttagtaaag gcaggttatc aattaagcga aaaaattaaa gaatggctgg cagaatttcc
    30961 tgagcaccca tcacaagaac aattgcttcc ttattatttt gatttgcttc attttttgaa
    31021 ggtcagtgaa ttttatgatg atcactacga aacaacagtc gaaaaaacgt atcgcgatct
    31081 gatagtaaaa gagttttgta ttgatccaag cttgtttctt gagcagtcgt tggataaagg
    31141 aaaaagcagt attctttttt ctgctagttt ttcaccactc tcttattatc aggaaacact
    31201 ggggggacaa aaaagtctgg cttacaaact gccgagtcct ttcccagaag gaaaccagca
    31261 agttttcatc gcaaattacc tagagacgac ttatcgaaaa agggaacaca gtctggcaaa
    31321 attagtagag acgattcatg cttttgctga tggaaaggtc gggaattatt tcgttttctt
    31381 tccttcttat caatatttag atcttgcggt ggaagcattc agacagcaat atcccgacag
    31441 caatgtgcta atccaagaaa cggacatgaa tgaggaagaa cgcgaacgat ttttaacaaa
    31501 atttcaaaca aatcccgctg aaacattgat tggattttgc gtacttggcg ggattttttc
    31561 agaaggaatc gatttgagag gggaccgatt gatcggcagt atgatcgtag gtgtaggttt
    31621 gccgcagatg aatcatgagc aggaactgat caaatcatat tatgatgaga aggaacacct
    31681 tggatttgct tacgcttatc agcttcctgg aatgaacaaa gtcttgcaag ctggtggtcg
    31741 agtgattcgt ggcatggcgg atcaaggaat cgttgtattg gcagatcaac gattttctag
    31801 tttttcttat cgacgtttat tcccacaaca ttggcaaaca gcaagagaag tacgaagtgt
    31861 tggggaattg gaagaaggaa tacagcgttt ttggttatca aaagaagcag taaatcaaaa
    31921 aaacgaggaa tgacagacgt cagcctcgtt ttttgattaa cgatagttag tgaattgcaa
    31981 ctcgattggt aagtcaagtt tacgtaataa agcaatcaca gcttgtagat catcacggtt
    32041 cttacctgtc actctaatct gatcttcttg gatttgtgct tttactttca gtttttcatt
    32101 tttgatagct gtagtgattt tcttcgcgtt ttcacgatcg attccgttga ccaaatcggc
    32161 agtttgtcga gctttgccac ctagagcgtg ttctgattcg gaaaaatgga tatttttgat
    32221 tggcacattt cttttgatca gcttaccaaa taatacatct ttgatctgtt cgattttgaa
    32281 atcatcatcg ctcaatacaa ctagattgct gttctctaat ttgatttcta ctgtagaatc
    32341 cttgaagtca aagcgattgg acaattcttt tgttgtttgc tgaatcgcat tttttacttc
    32401 ttctgtattg acttctgata caatgtcgaa gctagcatct tttgccatag gaaccctcct
    32461 gatatacata taaatattta ccatacatct atcttatcat aggattaggg cagattctta
    32521 cctgtttgct aaaattcttc tcatttgagt tcgaagtatt ttattttaat agataaactg
    32581 ttattcttac atttggaata ccaaagtagg ggagaggtgc ttgtgagtaa aattatgact
    32641 gcgtatcata aaaatgaaag attaaagaaa atagtggtta ttttgataac cggattgacc
    32701 gctgcggtcg ctttaaatta ttttttgatt ccagccaatg tcttttctgc agggatgaat
    32761 gggatcgctc aaatcatttc ctcgctttta tatgaatggt ttcatatcaa gatagacaca
    32821 ggaacattta tttttctttt gaatatccct gtgtttgtat tagggtttct caaagtagga
    32881 aaacgagcaa cgatccttag ttttgtgaat gttgtatgtg tatcggtgat gacgatgctg
    32941 cttccagtcg gacagatcac tgataatatt ttgatgaatg ccctagtagg cggtgtttta
    33001 ttaggtcttg gcgtaggatt atctttaaaa atgggcttta caactggtgg gatggatatc
    33061 atctctcttg tactttcaca aacaactgga aaaacagtcg gaaactacat gctgattcta
    33121 aatggtatca ttgtagtcat cgcaggcttc ttctttaact gggaaagtgc cttgtatacg
    33181 attatttcca tttatgcaat gactcaagta attgatgcca tccacacgag tcatcaaaaa
    33241 gtaacagcaa tgatcgttac cgtcaagcca gaagaggtaa cagaagaact agcaaaacgg
    33301 atggtacgtg gaatgacatt actgccgtct gtcggtggct attcaaaaaa acaagggaac
    33361 atgatcatga tggtcatcac ccgctacgaa atgtatgatc ttgatcagat cgttcatgaa
    33421 atcgacgacg atgcatttat caatatttta ccaactcatt cagtatttgg ccggtttgca
    33481 aatgaaaacg aacaaaaaat gtatcgaaca actggcgtat tgccagaaat aaaaaatcgt
    33541 tcacaaaaaa aatgaggaat caggtttatt ttagaataaa tttaatctat tacatctaat
    33601 aagaacattt ttataaattt aaacgagaat cttacttcta aattctcatt tacaagcagc
    33661 taaaaaaaga gtatgataaa taaaaatcgt gttaaggagt gtcgtacgat gagcgaagca
    33721 aaccaagaac ggtctggaca agaaatagaa ctaatcaaag aacgtattct tgctgccttg
    33781 gaaatggtga ttgatcctga attaggaatc gacatcgtca atttaggctt gatttatgat
    33841 atagaattca atcctgaaaa tggagaaaca gtcattaaga tgactctaac aactatgggc
    33901 tgtccattag cagatatttt aacagaatct atccatgacg cattaaaaga agtgccagaa
    33961 gtaacgaaag cagaagtcaa actagtctgg tatccagcat ggacgacaga taagatgagc
    34021 cgttatgcac ggattgcgtt ggggatacga tagaaatctt ggctgactag ctatgagaag
    34081 caaataggaa aaacaaaaaa gccttttatc ctttctagaa gaaaagagat aaaaggtttc
    34141 tttgtttata aaattttgtc tgctatatta taagttaatt aaataaatgt gttctattga
    34201 taaaggacat tcaaatccct ttccttttgg aatccttctt ttttacatca gtttgatttt
    34261 cgtatagtat tctttctcat cttcacgata aatcgcagcc ccattttttt gttgtgcttt
    34321 aagactgcca agattttttt tatttacaga caaaagtgcc tcatcaatgc cgattttttt
    34381 tgcctcttgt agtactaatg ctaatccttg tgtggcatat ccttttttac gataattagg
    34441 ggagatgccg taaccaatat ggccagcgcc gtttcttaat gtttcgttca gtttatggcg
    34501 caaattaaaa attcctacat actcatgttc atcactttct aaaataaaga cggttgcggg
    34561 aacgtaactc tcaggaagat cgattcctaa agacgttttt tcgcattttt ttacataatc
    34621 taaaaattca gcaaatgtat agccataagc attgttgata aatccactct catttggtcc
    34681 aaagctagtt tgtagctgat aagctttctt taaatctgct tcccatagtt tgatcagttt
    34741 catcgtattc acctctttaa gtaaccttat tcatttgttt tctactatag cactattgtt
    34801 gtaaatagcc atgcctattt ttatttattg tgtcatatcg tattaagaat catcgaacaa
    34861 tacaaatatg aattacaata aaaaaattat ttgaagttcg ttcattcgtt acttatgatc
    34921 tctagaagaa agaaaacgtg aattacttca gcgtctagaa ttccagaagg atagtaatca
    34981 acagaagaaa taatcaatat ccaaatgaaa gaagatagct gaatcgagaa aaagaggaaa
    35041 aaagaaatga agaaaaaaat aaaatagtta ctaatcccag agtcgttcgt ttaacattga
    35101 aatcgatcat atggataaaa cagatttttt caccaaccct caatagatga tggagttgct
    35161 cggatgaatt atttgtgtag atggcataag ggagggcgta cagaaatgaa aaagaacaaa
    35221 aatatgttct tgacaaaaaa cacatgtaat cctaaactaa aagatgtgat gcggctatgg
    35281 cggaattggc agacgcgcta gcttcaggcg ctagtgaggg tgacctcgtg gaagttcgag
    35341 tcttcttagc cgcataattt gtttttttat aaagagaagg tacacctgga gcgatgagaa
    35401 agaaaataac atattatcta aaagaatata ggaaaaattt taaacaacgg aaccagattc
    35461 aaataaatca aaaaaaattt gtgtgaaggt gggacagttt aaaacctaat agattgattc
    35521 aaatagtaga tttatagatt ctgatacaag aaatactggc aaacgatagt taaggaataa
    35581 agactaaact taaactcaaa aagaggtcat gcgaaagaat aaatcgcatg acctcttact
    35641 atattttgaa tgtgtttaaa cgttcaaata atgaatctta gtaccaaccg tttgcttccc
    35701 agaatgcttt cgccgcttcc caagaaccat aacgtgaagt aacatattgt tctgctactc
    35761 tttcttggtt tgcagcagag tagtcaccat ttaagtaaga agaatctaat tggtaacggc
    35821 cgatgtaacg tccgttcgtt gctgtgtaag aaccgcttga ttctttttgt gcgatccatt
    35881 cttttgcaga gcttgtactt gctggagtag cagcagtttc tgttacagca ggagcaggtt
    35941 gtgtttcagc aacaggcgct gcttgtgttt ccgtttgaac cgtttcttgt acaacaggtt
    36001 gttcagcttg aacaggttca gcttggactg gtgcttcttg aacggctgct tgaggttcag
    36061 cagctgcttg tgcagagcct tctgttggga ttgttaattg ttgtcctgag ta
//
LOCUS       DAZKKZ010000028        34688 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.028, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000028 DAZKKZ010000000
VERSION     DAZKKZ010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 34688)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34688)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34688
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.028"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            591..1280
                     /locus_tag="ACG8LA_001419"
     CDS             591..1280
                     /locus_tag="ACG8LA_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFQ0203724.1"
                     /translation="MKILIADDDKEIVELLSIYVHNEGYEAVKAYDGKEALSKIRTIP
                     DIELLILDIMMPEMDGMQVVKELRKESQIPIIMLTAKTTDMDKIKGLVAGADDYVTKP
                     FNPLEVMARVKSLLRRTKMQIAPDQPDVLEVNALIINKDSHEVKTIDGKEIQLTALEF
                     GILYLLASHPNRVFSADEIFERVWKQESIVSAKTVMVHVSHLRDKIEEATGGEKVIQT
                     VWGVGYKIDAR"
     gene            1267..2475
                     /locus_tag="ACG8LA_001420"
     CDS             1267..2475
                     /locus_tag="ACG8LA_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="HFQ0203725.1"
                     /translation="MTQDSKRATEKRRRINLTSKEISELLAEGIITIILLLLLNVSIL
                     VVISSVINSSPSLTNAIWDSKNIFAERLNTDLFWNGRNFIIPFFFLLDIGVLYWRLIR
                     RYRQMQLRHIISELHYIANGNYDHRIPFELSGDLSRVVTSINGLVDSTVAAIEDERKI
                     EKSKDELITNVSHDIRTPLTSIIGYLGLIEDGQYHSEEDLLKYTHTAYIKAKQMKSLV
                     DDLFEYTKVRQPAVPVNFSAFDMIQLIEQLAADFELEASKKNIQILVQSKVDSLIMDG
                     DTEKLVRVFNNLLTNALKYGKGATKIVIEVERIGSEVVATVKNNGAMIPQQAIDNLFD
                     RFYRVEESRSQATGGTGLGLAIAQSIVALHGGYIYAKSDKQWTSFIMHLPIKKNEKLP
                     IDTQEVIDES"
     gene            2769..4040
                     /gene="serS"
                     /locus_tag="ACG8LA_001421"
     CDS             2769..4040
                     /gene="serS"
                     /locus_tag="ACG8LA_001421"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004828 - serine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006434 - seryl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HFQ0203726.1"
                     /translation="MLDVKMMRQNIEEVQEKLMTRGVKKETLAEFMELDENRRKLLVK
                     SEELKKYRNDVSAEIAQLKRAKEDASAKIAEMKEVGGNIKALDTEIAEVDEKLKQIAT
                     TLPNLPHDSVPVGTDEEDNVEIRRWSEPRTFAFEPKPHWEIAENLDILDFERGAKVAG
                     SRFVYYKGLGARLERAVYNFMLDQHIYEHGYTEMITPYIVNSKAMFGTGQFPKFKEDV
                     FQLENTDLTLIPTAEVPLTNYYNDEILDGADLPIYFTALSPAFRSEAGSAGRDTRGLI
                     RLHQFNKVEMVKFSDVEHSYEELEKMTADAEDILKKLHLPYRVMALSTGDMGFSAAKT
                     YDLEVWIPAQDTYREISSCSNCEDFQARRAMIRYRDNDGKIHYTHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTVPEALVPYMGNLKVIK"
     gene            complement(4589..6073)
                     /gene="guaB"
                     /locus_tag="ACG8LA_001422"
     CDS             complement(4589..6073)
                     /gene="guaB"
                     /locus_tag="ACG8LA_001422"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003938 - IMP dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HFQ0203727.1"
                     /translation="MSNWETKFTKKGFTFDDVLLIPAESHVLPNEVDMSVQLAKNIKL
                     NIPIISASMDTVTDSKMAIAMARQGGLGVIHKNMTISQQADEVRKVKRSESGVIIDPF
                     FLTPQHLVADAEELMSKYRISGVPIVETLENRKLVGIITNRDMRFVTDYHMPIADVMT
                     KDNLVTAPVGTSLKDAEKILQKHKIEKLPIVDNEGRLSGLITIKDIEKVIEFPNAAKD
                     EHGRLLVAAAVGVTSDTFERANALLEAGADAIIIDTAHGHSAGVIRKIQEIRSTFADA
                     TLIAGNVATAEATKALYDAGVDVVKVGIGPGSICTTRVVAGVGVPQLTAIYDAASVAR
                     QYGKAIIADGGIKYSGDIVKALAAGGHAVMLGSMLAGTDESPGEFEIFQGRRFKTYRG
                     MGSLGAMEKGSKDRYFQGSVNEANKLVPEGIEGRVAYKGSVADIIFQMIGGLRSGMGY
                     VGAANLQQLRDEAQFIQMSGSGLKESHPHDVQITKEAPNYSVES"
     gene            complement(6578..7273)
                     /locus_tag="ACG8LA_001423"
     CDS             complement(6578..7273)
                     /locus_tag="ACG8LA_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HFQ0203728.1"
                     /translation="MEPEQLRAIVKENNSLETKLTKRNQQYIFDLKKSLEAANLSEEE
                     KVKALHDILPTLVAEQKGGRTARQLFGTVSERTEAIINKPAEVKNSSTPLLMWLDNTL
                     LLLGLLSIMIAITGLFSRGTTPAYGFSTLVLGSAIGGWVFYMMYKYIYQYEYPGADRS
                     KKPGMGKTLLILGGTTLLWVVLFSATTLLPPVINPVLDPVVVIIIGATALAIRYYLKK
                     KYGIIGSLSVPRR"
     gene            complement(7363..8463)
                     /gene="ychF"
                     /locus_tag="ACG8LA_001424"
     CDS             complement(7363..8463)
                     /gene="ychF"
                     /locus_tag="ACG8LA_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HFQ0203729.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDWRLQRLTELVHPKKTVPTTFEFTDIAGIVKGASKGEGLGNQFLSHIRQVDAICH
                     VVRCFDDDNITHVEGRVDPLEDIDTINLELVLADLESINKRYTRVAKVAKTKDKDAVA
                     ELAVLDKIKPVLEEGKSARTIEFTEEEQKIVKSLFLLTTKPILYVANVSEDDVADADA
                     NHYVQEVRNFAAEENAEVIVVSARAEEEIAELDEEDKAEFLEALGIEESGLDQLIRAA
                     YDLLGLATYFTAGEQEVRAWTFKKGIKAPQAAGIIHSDFERGFIRAETVSFEDLDHYG
                     NMHAAKEAGRVRLEGKDYVVQDGDVMLFRFNV"
     gene            complement(8472..8663)
                     /locus_tag="ACG8LA_001425"
     CDS             complement(8472..8663)
                     /locus_tag="ACG8LA_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 domain-containing protein"
                     /protein_id="HFQ0203730.1"
                     /translation="MYDLHDIVEMKKPHACQTNRWEVIRMGADIKIRCMNCGHIVMMT
                     RRDFEKKLKKVIEKNAEKE"
     gene            complement(8684..9574)
                     /locus_tag="ACG8LA_001426"
     CDS             complement(8684..9574)
                     /locus_tag="ACG8LA_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HFQ0203731.1"
                     /translation="MKKSKGLGRGIDALFQDLENLETVDVKDDTVVQLPLNELRPNPY
                     QPRKTFEEVSLQELANSIEQSGVFQPIIVRRSAVKGYEIIAGERRFRASKLAEKETIP
                     AIVRDFDEEAMMQVAVLENLQREDLNPLEEAEAYEMLMKNLKLTQAEVASRLGKSRPY
                     IANYLRLLSLPDLVKEMVQDQRLSMGQARTLLGLKNKTLILKLANRAVTENLTVRQLE
                     QLVSELNQNDGKEKKKIPRLAKEKPYYIRESEDRLMDKFGTSVAIQEKNGKGKIEIEY
                     LSQKDLTRILDILNIQFDEE"
     gene            complement(9561..10328)
                     /locus_tag="ACG8LA_001427"
     CDS             complement(9561..10328)
                     /locus_tag="ACG8LA_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HFQ0203732.1"
                     /translation="MAQIISVANQKGGVGKTTTTVNLGACLASLGKKVLLVDMDAQGN
                     ATSGVGIRKPDVTRDIYDVLVNELPIDEATLITEHENLSIVPATLQLAGAEIELTSMM
                     ARESRLKGSLAEVSSQYDYILIDCPPSLGHLTINSFTASDSILIPVQCEYYALEGLSQ
                     LLNTVRLVQKHFNPELEIEGVLLTMYDARTNLGNEVVEEVRKYFREKVYETIIPRNIR
                     LSEAPSHGKPIIDYDPRSRGAEVYQALAKEVVSREEK"
     gene            complement(10340..11053)
                     /gene="rsmG"
                     /locus_tag="ACG8LA_001428"
     CDS             complement(10340..11053)
                     /gene="rsmG"
                     /locus_tag="ACG8LA_001428"
                     /EC_number="2.1.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005575 - cellular_component [Evidence
                     IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0031167 - rRNA methylation [Evidence IEA];
                     GO_process: GO:0046118 - 7-methylguanosine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HFQ0203733.1"
                     /translation="MIPEEFRQSLAEKGIELTDHQMNQFAIYYRTLVEWNEKMNLTAI
                     TDEKDVYLKHFYDSLTLAFEVDFTQPLSLCDVGSGAGFPSIPLKIAFPELQITIVDSL
                     NKRITFLSELTRLLGIDASLYHDRAETFGQNPHFRASFDLVTARAVARLNVLAELCLP
                     LAKQEGYFYALKAAKSEEELTEAKQAIALLGGKFLKEEAVTLPNVSDQRHIIVIQKKK
                     PTPKKYPRKPGLPNKQPIK"
     gene            complement(11285..13186)
                     /gene="mnmG"
                     /locus_tag="ACG8LA_001429"
     CDS             complement(11285..13186)
                     /gene="mnmG"
                     /locus_tag="ACG8LA_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002098 - tRNA wobble uridine modification
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HFQ0203734.1"
                     /translation="MEHYEADAYDVIVVGAGHAGSEAALAAARMGSKTLLLTINLDMV
                     AFMPCNPSVGGPAKGVVVREIDALGGEMGKNIDKTYIQMRMLNTGKGPAVRALRAQAD
                     KHAYSTEMKHTIEKEPNLTLRQGIVEELIVEDGVCHGVVTSTGASYRAKAVVITAGTA
                     LRGEIIIGELKYSSGPNNSQPSIGLANHLKELGFAIERFKTGTPPRVKSSTIDYSVTE
                     EQPGDKEPNHFSFSTPDSAYKLDQESCWLTYTGETTHQIIRDNLHRAPMFTGIVEGVG
                     ARYCPSIEDKIVRFADKPRHQLFLEPEGLNTEEVYVQGLSTSLPEDVQVNMLHSIAGL
                     EKVEMMRTGYAIEYDVVEPHQLRPTLETKVVENLYTAGQTNGTSGYEEAAGQGLIAGI
                     NAALKVQGKEPLVIKRSDGYIGVMIDDLVTKGTNEPYRLLTSRAEYRLLLRHDNADLR
                     LTEMGHRVGLVKEDQYKNYLKKKEAVEQEIKRLMNVRIKPTEEVQDFLATINAAPLKD
                     GVLASDFLRRPEITYAELLRFIPENEELTRKEIEQVEIQIKYEGYIKKAMEKVEKLKR
                     MEAKKIPENIDYAAINGLATEAKQKLQKIQPETIAQASRISGVNPADLSILMVYIEQG
                     KIAKVSEPA"
     gene            complement(13203..14600)
                     /gene="mnmE"
                     /locus_tag="ACG8LA_001430"
     CDS             complement(13203..14600)
                     /gene="mnmE"
                     /locus_tag="ACG8LA_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HFQ0203735.1"
                     /translation="MAEITLEFDTIAAISTPPGEGAISIVRLSGDQAVQLADKVYQSG
                     NKRLSEVPSHTIHYGHIVDPKSNQLVDEVMVSVMRAPKTFTREDVVEINCHGGIVVVN
                     QILQLLLREGARLAEPGEFTKRAFLNGRVDLSQAEAVMDLIRAKTDKAMGLALNQLDG
                     NLSALIRSLRQEILETLAQVEVNIDYPEYDDVEELTTKLLLEKAQMIQQRIQALLATS
                     KQGKVLREGLSTAIIGRPNVGKSSLLNHLLREEKAIVTDIAGTTRDVIEEYVNVRGVP
                     LKLIDTAGIRETEDVVERIGVERSRKALAEADLILLVLNQSEPLTAEDEQLLEATSGL
                     KRIILLNKTDLPAQLEQEKLKKLIENEPVFSISVAKNDGLDRLESAISDLFFSGETGE
                     RDATYVSNTRHIALLEKASLSLEEVIAGIDSGMPVDLVQIDMTRCWDYLGEVVGDSVQ
                     DELITQLFSQFCLGK"
     gene            14899..15282
                     /locus_tag="ACG8LA_001431"
     CDS             14899..15282
                     /locus_tag="ACG8LA_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0203736.1"
                     /translation="MVALSKLYTFERRKYVSPFRSAALEEESDPRINDVVLSTGNINQ
                     KYIVRDIVFVVECLEADLFDPSFPKDDLFLTTKRKLKTKVLEYGANAVINCHFEYQQK
                     KRDGKYFLELFAYGTVIQFIQTTIG"
     gene            complement(15450..16208)
                     /gene="jag"
                     /locus_tag="ACG8LA_001432"
     CDS             complement(15450..16208)
                     /gene="jag"
                     /locus_tag="ACG8LA_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding cell elongation regulator Jag/EloR"
                     /protein_id="HFQ0203737.1"
                     /translation="MPIYEAATIDEAVQLGLADLGLAKDQVEIEILEEGKKGFLGMGR
                     KNARLSIQPSISEKVSETVEQTVEEILEEEPTAEIEVVNETILEEKTEEVSELGDEAA
                     LTELAVYLTEISKQLDAPALVKMERESNNMVVFHLETQKQGILIGKHGKTLNALQYLA
                     QVFIHRLARNKLSVVVNVGNYREKRQEIIQRLADRTAEKVKRTGQPVFLEPMPAFERK
                     QIHAALSKDEHVKTHSEGEEPYRYLVVEPAKKYY"
     gene            complement(16226..17044)
                     /locus_tag="ACG8LA_001433"
     CDS             complement(16226..17044)
                     /locus_tag="ACG8LA_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0032977 - membrane insertase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YidC/Oxa1 family membrane protein insertase"
                     /protein_id="HFQ0203738.1"
                     /translation="MKKYKRLLLMAGIVSLVIVLSGCGTGEVSAQSTGIWDRYIVYYF
                     AEAIKALSFGNAGIGIILFTLIIRVILLPLMHFQTKSMRKTQELQPKLKALQQQYSSR
                     DPETQSKLREEQQRLYAENGVNPYAGCLPLLVQMPILMALWQSISRVPELKQGHFLWL
                     NLGNADPTFILPILAAIFTFASTYLSSMSQIESNASMKIMNFVMPVMILVMGVNLASG
                     LSLYWVVSNAFQVVQTLLINNPFKIRKEREEEARRIRERERALKKAMNPKKKRK"
     gene            complement(17041..17397)
                     /gene="rnpA"
                     /locus_tag="ACG8LA_001434"
     CDS             complement(17041..17397)
                     /gene="rnpA"
                     /locus_tag="ACG8LA_001434"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0004526 - ribonuclease P activity
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HFQ0203739.1"
                     /translation="MRKAYRVKKEREFQAVFHTGDSFANRKFVVYRLEKPGQPHFRVG
                     LSVGKKVGNAVNRNEVKRKIRAAVYSIKEEIDPELDFIVIARPSVKGLTYDEVRSNLV
                     HVLKLAKIIDREEKSK"
     gene            complement(17515..17649)
                     /gene="rpmH"
                     /locus_tag="ACG8LA_001435"
     CDS             complement(17515..17649)
                     /gene="rpmH"
                     /locus_tag="ACG8LA_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003397591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HFQ0203740.1"
                     /translation="MKRTYQPNKRKRQKVHGFRKRMSTKNGRRVLASRRRKGRKVLSA
                     "
     gene            18173..19507
                     /gene="dnaA"
                     /locus_tag="ACG8LA_001436"
     CDS             18173..19507
                     /gene="dnaA"
                     /locus_tag="ACG8LA_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003688 - DNA replication origin binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA];
                     GO_process: GO:0006275 - regulation of DNA replication
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HFQ0203741.1"
                     /translation="MVSLDALWNELKATYQKDLSPASYNTWIETANPRTLDQNQLVVE
                     VPSKIHKEYWEKNLATKIVEVGYMLSGNEIIPRFITGEEAEQEEVIEEKNPKVVAPSP
                     LKKAMLNPKYTFDTFVIGKGNQMAHAAALVVAEDPGSIYNPLFFYGGVGLGKTHLMHA
                     IGHQMLQSQPNAKVKYVSSETFANDFINSIQNKTAEEFRQEYRNVDLLLVDDIQFFAE
                     KEATQEEFFHTFNALYNEGKQIVLTSDRLPNEIPKLQERLVSRFAWGLSVDITPPDLE
                     TRTAILRKKAAAERLEIPDDTLSYIAGQIDSNIRELEGALVRVQAFAAMNSEDISTSL
                     AADALKTLKSGKGHPQLSILQIQEEVAKYYHIQLKDIKGKKRVKSIVVPRQIAMYLAR
                     ELTDNSLPKIGAEFGGKDHTTVIHAHEKIQQLMDSSVSMQNEVSEIKNFLLN"
     gene            19705..20835
                     /gene="dnaN"
                     /locus_tag="ACG8LA_001437"
     CDS             19705..20835
                     /gene="dnaN"
                     /locus_tag="ACG8LA_001437"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009360 - DNA polymerase III complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HFQ0203742.1"
                     /translation="MKVTLNRASFMQELQTVQRAISSKTTIPILTGVKITLTQEGLTL
                     TGSNADISIETFLSVENEKANMQIESTGSIVLQARFFSEIIRRLPEETFTLEVLENKQ
                     VAITSGKANFIVNGLDADNYPHLPVVESHNQMKLPVHVLTKLINETVFAVSQHESRPI
                     LTGVHFILSDNSLLAVATDSHRLSQRVIPVEQAADHFDIVIPGKSLIELSRSLTNEEE
                     IVEISIMENQVLFKTETMYFYSRLLEGNYPDTNRLIPSSFNTEVEFSVPSFLAAIERA
                     SLLSHEGRNNIVRLSIRPDAVVLYGNSPEIGKVEESLSYTASSGDPLDISFNPDYMKA
                     ALRAFGDMSIKVKFISAIRPFTLEPTEDGVQFIQLITPVRTN"
     gene            21064..21306
                     /gene="yaaA"
                     /locus_tag="ACG8LA_001438"
     CDS             21064..21306
                     /gene="yaaA"
                     /locus_tag="ACG8LA_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HFQ0203743.1"
                     /translation="MKQQVILNTEFMTLGQMLKEVTVIGSGGQAKWYLAENTVLVDGE
                     PENRRGRKLYPGMMVEVPEVGTFFMVKKGNDDNEAE"
     gene            21293..22417
                     /gene="recF"
                     /locus_tag="ACG8LA_001439"
     CDS             21293..22417
                     /gene="recF"
                     /locus_tag="ACG8LA_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HFQ0203744.1"
                     /translation="MRLNKLYLKNYRNYEELNIEFSKNLVIFLGENAQGKTNLLESIY
                     VLAMTRSHRTSSEQELIGWTDDQAMIQGEITKGSSTLPLEILLSKKGRKTKINHIEQK
                     KLSTYVGQMNVILFAPEDLSLVKGSPQIRRKFLDMELGQINPIYLYDLVQYQAILKQR
                     NQYLKQLNEKKQTDLLYLDILSEQLAAFGSKVLKARAQFVKRLEFWANSLHQQITHQK
                     EQLEIEYLTAVDSLETHTQEQIQEQFLALLNQNKKKDLFRGTTTVGPHRDDLSFFINQ
                     KNVQTYGSQGQQRTTALSVKLAEIDLIKEETGEYPILLLDDVMSELDDSRQLHLLETI
                     EGKVQTFLTTTTLDHVKNKMTVEPEIFYVQQGKLKGEETE"
     gene            22414..24360
                     /gene="gyrB"
                     /locus_tag="ACG8LA_001440"
     CDS             22414..24360
                     /gene="gyrB"
                     /locus_tag="ACG8LA_001440"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003129249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HFQ0203745.1"
                     /translation="MTEERSLVERAKEYDASQIQVLEGLEAVRKRPGMYIGSTSSEGL
                     HHLVWEIVDNSIDEVLAGFATKIHVIIEKDNSITVIDDGRGIPVDIQAKTGRPAVETV
                     FTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVKVYKEGNVYYQEYRRGAVVD
                     DLKIIEQTDRHGTTVHFTPDPEIFTETTEFDFSKLATRIRELAFLNRGMRISIEDKRE
                     EEPVINEYHYDGGIKSYVEYLNANKTVIFPEPVYLEGEQQDIAVEVSMQYTDGYHSNI
                     MSFANNIHTYEGGTHESGFKTALTRVINDYARKQKLMKENDDNLTGEDVREGLTAVIS
                     IKHPDPQFEGQTKTKLGNSEVRTVTDRLFSEHFMKFLLENPSVGRQIVEKGLLASRAR
                     LAAKRAREVTRRKGALEISNLPGKLADCSSNDPEKCELFIVEGDSAGGSAKQGRNREF
                     QAILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGEDFDVSKARYHKLVIMTDA
                     DVDGAHIRTLLLTLFYRYMRPIVEAGYVYIAQPPLYGVKQGKNITYVQPGKNAEEELK
                     QVVASLPASPKPSVQRYKGLGEMDDHQLWETTMDPSNRMMARVSVDDAIAADQIFEML
                     MGDRVEPRRAFIEENAHYVKNLDI"
     gene            24380..26851
                     /gene="gyrA"
                     /locus_tag="ACG8LA_001441"
     CDS             24380..26851
                     /gene="gyrA"
                     /locus_tag="ACG8LA_001441"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006259 - DNA metabolic process [Evidence
                     IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HFQ0203746.1"
                     /translation="MSEEIRENIHDVNLTSEMKDSFIDYAMSVIVARALPDVRDGLKP
                     VHRRILYGMNELGVTPDKAHKKSARIVGDVMGKYHPHGDYAIYESMVRMAQPFSYRYM
                     LVDGHGNFGSVDGDGAAAMRYTEARMSKIATEMLRDINKNTVDFQSNYDDTEKEPVVL
                     PARFPNLLVNGTTGIAVGMATNIPPHNLSEVVAAIDLLMDNPDVTTNELMEVLPGPDF
                     PTGGLVMGKSGIRRAYETGKGSITVRAKVEITEMPNGKERIIVTELPYMVNKAKLIER
                     ISELHRDKRIEGITDLRDESSREGMRIVIDIRRDASASVILNNLYKLTSLQNSFGFNM
                     LAIEKGVPKVLSLKQILENYIEHQREVITRRTVFEKEKAEARAHILEGLRIALDHIDE
                     IIAIIRGSKSDDEAKATMIERFDLSDRQSQAILDMRLRRLTGLEREKIENEYQELLKL
                     IEDLTDILARPERVTEIIKNELADLNQRFGDKRRTELLVGEVLSLEDEDLIEEEEIVI
                     TLTNNGYIKRLANNEFRAQRRGGRGVQGMGIHNDDFVKNLVSCSTHDTLLFFTNNGKV
                     YRAKGYEIPEYGRTAKGIPIINLLGIDSSESIQAIIAVTGEAEEGHYLFFTTRQGTVK
                     RTSVTAFANIRSNGLIAIGLKEDDELVNVLLTDGQSNIIIGTHNGYSVTFKEEAVRDM
                     GRTASGVRGIRLREEDYVVGAALMKEDQEVLVITEKGYGKRTKVSEYPVKGRGGKGIK
                     TANITEKNGPLAGLTTVSGDEDIMLITDKGVIIRFNVSTVSQTGRSTLGVRLMKMEAD
                     TKVVTMAAVEPEAAEQTVEEQGSEE"
     gene            27087..27386
                     /gene="rpsF"
                     /locus_tag="ACG8LA_001442"
     CDS             27087..27386
                     /gene="rpsF"
                     /locus_tag="ACG8LA_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005226363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HFQ0203747.1"
                     /translation="MENTKYEIMYIIRPNIDEEAKTALIERFDAILKDNGAEVIESKD
                     WEKRRFAYEMNGYREGIYHIVKVSSPSSANAVNEFDRLAKINDDIIRHMIVKEEA"
     gene            27436..27948
                     /gene="ssb"
                     /locus_tag="ACG8LA_001443"
     CDS             27436..27948
                     /gene="ssb"
                     /locus_tag="ACG8LA_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HFQ0203748.1"
                     /translation="MINNVVLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQSGNR
                     EADFINCVIWRKSAETLANYARKGTLLGVTGRIQTRSYDNQQGQRVYVTEVVADNFQL
                     LESRSASENRQQSGGFQSSGQSAGGFGGNNNSNQTSQSSNGMPDFDRDTSDPFGSSST
                     IDISDDDLPF"
     gene            27974..28210
                     /gene="rpsR"
                     /locus_tag="ACG8LA_001444"
     CDS             27974..28210
                     /gene="rpsR"
                     /locus_tag="ACG8LA_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HFQ0203749.1"
                     /translation="MAQQRRGGRKRRKVDYIAANHIEYIDYKDIELLKRFISERGKIL
                     PRRVTGTGAKNQRKITVAIKRARIMGLLPFVSED"
     gene            28353..30326
                     /locus_tag="ACG8LA_001445"
     CDS             28353..30326
                     /locus_tag="ACG8LA_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HFQ0203750.1"
                     /translation="MENKNNHLSPKPLFLILFILIEVLVVLILPFRFVSASVILLMNL
                     WGVRYWLKMKRWLILNKREKIQQASTVAETNLAYVSEVMPVGVIAYQPSSQKIEWLNP
                     LALKIKDQSGLTEEELLDTFFTAKEKKKNQVYLADKTFQFDMDTVKGVVYFNDITQNQ
                     LLKLHQTNSQPVIGILSIDNYADAIDKLDDKEISYLNSFVTTLVSDWMNEYHVFFKRI
                     NAERFFFVAQMIDLKKMMDKKFDLLDRFRAEAEKQSSPITLSMGIAYGSRTLDEIGGE
                     AQNNLDVALVRGGDQVVVKEVKEGAKPVYYGGKSAKNVKRTRVRSRAMSTALRRIFDE
                     TGDVFIMGHKFPDMDALGSAFGVSCLARFNQKKAYIVINENEIIPDVERCLEEIHKHP
                     ELEMQLISPERAIELKKEEDLLVMVDYHKPSLSISQGLYEQFDKIVIIDHHRRGEEFP
                     SKPLLTYIESSASSASELVSELIQYQSSKTNRLDRFEATLLLAGMVVDTNSFNVRTTA
                     RTFDVASYLRSCGADASLVQYLLSSDLATYLEISNLIAGSDYVTSDIVVAAGTDEKEY
                     NSVIAAKTADTLLSMININAAFVITKRTDGLIGISARSTGTINVQIIMESLGGGGHFT
                     NAATQLENTTVEETKQKLFAAIKENMNQIYDKE"
     gene            30332..30784
                     /gene="rplI"
                     /locus_tag="ACG8LA_001446"
     CDS             30332..30784
                     /gene="rplI"
                     /locus_tag="ACG8LA_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HFQ0203751.1"
                     /translation="MKVIFLQDVKGKGKKGDIKEVPAGYAQNYLIKNNLAKEATKSSI
                     SQLAGQKKAQEKHEAEILEEAKKLKEFLEKEDTVVELKAKAGEDSRLFGSIPSKQIAE
                     GLNKQYKIKLDKRKIELENPIRSLGYTNVPVKLHHEVTATIKVHVVQE"
     gene            31058..32425
                     /gene="dnaB"
                     /locus_tag="ACG8LA_001447"
     CDS             31058..32425
                     /gene="dnaB"
                     /locus_tag="ACG8LA_001447"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HFQ0203752.1"
                     /translation="MNEVWQDRIPPQNIEAEQAVLGSVFLDAETIIDAMEYIEPKDFY
                     RRGHQIIFETMIELNDRNEAIDVVTVKDRLEQANLLEDAGGLSYLSDLALAVPTAANI
                     VYYAKIVEEKSLLRTLIQTATGIVTKGFEQGEEVQTILDDAERSILEVSEKRNRSGFL
                     SIAEVLNSTIENIDRLAQNNEEITGLPTGYQGLDKMTAGFQPEELIILAARPAVGKTA
                     FALNIAQNVGTKTDRSVAIFSLEMGAESLVNRMLCAEGSIEASHLRTGQLSEEEWSNL
                     IVAMGSLSRANIFIDDTPGIKISEIRAKCRKLAQEKGNLGLILIDYLQLIEGNGKENR
                     QQEVSDISRQLKKLAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYEREGGDDDDGNEPKNDNVIEVIIEKNRSGARGTVELLFIKEYNKFSSLS
                     PREEF"
     gene            33205..34497
                     /locus_tag="ACG8LA_001448"
     CDS             33205..34497
                     /locus_tag="ACG8LA_001448"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004019 - adenylosuccinate synthase
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HFQ0203753.1"
                     /translation="MSSVVVVGTQWGDEGKGKITDFLSENAEVIARYQGGDNAGHTIK
                     FNGVTYKLHLIPSGIFYKDKISVIGNGVVVNPKSLVKELAYLHEKGVETSNLRISDRA
                     HVILPYHIKLDQLQEDAKGENKIGTTIKGIGPAYMDKAARVGIRIADLLDKEIFEERL
                     RLNLDDKNRQFVKMFDSEPLDFDDIFEEYYEYGQQIKQYVTDTSVILNDALDAGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKINKVVGVCKAYTSRVGDGP
                     FPTELFDETGEQIREVGREYGTTTGRPRRVGWFDSVVMRHSKRVSGITNLSLNSIDVL
                     SGLETVKICTAYELDGELIYHYPASLKELNRCKPIYEELPGWSEDITGCKTLAELPEN
                     ARNYVRRISELVGVRISTFSVGPDRTQTNILESVWAQI"
BASE COUNT        10563 a         6737 c         6861 g        10527 t
ORIGIN      
        1 ggagtgtttc ccgattcgtt tttggctgcc gtagcaactt ttatatcata tcagagagac
       61 aagtaattgt caactctttt ttaaaagttt tttcgatttc gtttttcgaa atcttccagc
      121 aactcattta tcataactta tcgtttgtta tttgtcaaga acttttttga agtttttttc
      181 gatagaatca agcttcgcaa gtggttcttt tttaacgact cagttatctt atcatgtcat
      241 ttccaacatg tcaacaactt attttttatt atttaataag ttattggtgt tcttttgaac
      301 aaataataat atatcaacat cacatgtgaa agtcaataag aaaatgctta tttatcaaca
      361 tttctagctt acatgatcat tggttagttc tggtcctttt tcgttcgtct ttataactcc
      421 gagagacgta aaatcctttt gttttcagtt taatgttcat gttcttgtct tattcacacc
      481 aactagatgt ctcaccttct aaaattttcc ttaacaaagt gctgctttta tctatttctg
      541 cttttttttg ctagaataat agtaacaata tgactctgga ggatttattt atgaaaattt
      601 tgattgctga cgatgataaa gaaatcgttg aattattaag tatctatgtt cacaatgagg
      661 ggtatgaagc agtaaaggct tatgatggga aagaagcatt atctaaaatc agaacaatcc
      721 ctgatattga attacttatt ttagatatca tgatgcctga gatggatggg atgcaagtag
      781 tgaaagagct acgaaaagaa tcccaaatac caatcattat gctgacagca aaaactactg
      841 atatggataa gatcaaagga ctggtcgctg gtgcagatga ttatgtgacc aagccattta
      901 atccgttaga agtaatggct agagtaaagt ctttattacg gcgtacaaaa atgcagattg
      961 ccccagatca gcctgatgta ttagaagtaa atgcattaat catcaataaa gactctcatg
     1021 aagttaaaac aatcgatggg aaagaaatcc agttaacagc tttggaattc ggtatcctct
     1081 acttgcttgc tagtcatcct aatcgagtat ttagcgcgga tgaaattttt gagcgtgttt
     1141 ggaaacaaga aagtattgtc tctgctaaaa ctgtcatggt tcacgttagt catttaagag
     1201 ataagattga agaagcaact ggtggtgaaa aagtcattca aaccgtttgg ggagtgggct
     1261 ataaaattga cgcaagatag taaacgagca actgaaaaac gccgtcggat caatttgact
     1321 tcaaaagaaa tcagcgaatt gttagcggaa ggaatcatca cgattatcct tttgcttcta
     1381 ttaaatgttt ctattctggt tgttatcagt tcggtgatca acagttcacc ttctttgacg
     1441 aatgcgattt gggattcaaa gaatattttt gcagaacgat tgaacactga tttgttctgg
     1501 aacggccgga attttattat tccctttttc tttctattag atattggtgt tttgtattgg
     1561 cgcttgattc gaagatatcg ccaaatgcaa ttgcggcata tcatcagcga acttcactac
     1621 atcgcaaacg gaaattatga tcatcgtatc ccttttgaac tgagtggtga cttaagccga
     1681 gtggtaacaa gtatcaatgg attggtggat agtaccgtag cagcgattga agacgaacgt
     1741 aaaatcgaaa aatcaaaaga tgaattgatc acgaatgtca gtcatgatat ccgtacccca
     1801 ctcacgtcca tcattggata cctaggactg atagaagatg gccagtatca ctcagaagaa
     1861 gatcttttaa agtatacgca tactgcttat atcaaagcaa agcagatgaa atctttagtg
     1921 gacgacttat ttgaatacac taaggtacgc cagcctgctg tcccggtgaa tttttctgcc
     1981 tttgacatga tccagttgat cgaacagtta gcagctgatt ttgagttgga agcttctaaa
     2041 aaaaatatcc aaatacttgt tcaatcaaaa gtagactccc ttatcatgga tggcgatacc
     2101 gaaaaacttg tacgtgtctt caataatctt ttgacgaatg cgttgaaata cggaaaagga
     2161 gcaacgaaga tcgtaatcga agtagaacgt atcggttcag aagttgttgc aacagtcaaa
     2221 aataacggag caatgatccc acaacaggca atcgataatc tattcgaccg tttttatcgt
     2281 gtagaagaat ctcgttcaca agcaactgga ggaactggac ttggtttagc aatcgctcaa
     2341 agcattgtgg ctttgcacgg cggatacatt tatgcaaaat cagataagca atggacttct
     2401 ttcatcatgc accttccaat caagaaaaat gaaaaattac ctattgatac acaggaagtt
     2461 attgacgaaa gctgaaatat tcgctattct tattacaatt attagaataa atgaaaaaca
     2521 cagaacccag tacactttat tctttttcag agagctgatg gcaggtgtaa atcagcaaag
     2581 gataatttgg aagttccagt tcgtttacgt gccctttcga aataagaaag gtcggttcaa
     2641 cagccgttat gtgttcaaca agtgcagctg acgctgaact tgggtggtac cgcgaatttc
     2701 agactgattc gtcccaagaa taatgggatg gatcagtctt tttttatttt caaaaaggag
     2761 gaaatcatat gttagatgta aaaatgatgc gacaaaatat tgaagaagta caagaaaaat
     2821 tgatgactcg gggcgtaaaa aaagaaacat tagctgaatt catggaacta gatgaaaatc
     2881 gtcgtaagct actagtcaaa agtgaagaat taaaaaaata tcgaaatgat gtttctgctg
     2941 agatcgccca attgaagcgt gcaaaagaag atgcttctgc taaaatcgct gaaatgaaag
     3001 aagtcggtgg caacatcaaa gcattggata ctgaaattgc tgaagtggat gaaaaattga
     3061 aacaaattgc aactactttg ccaaaccttc cccatgattc tgtgccagtt ggaacagatg
     3121 aagaggacaa tgtagaaatc cgtcgttgga gcgaaccacg tacatttgct tttgaaccaa
     3181 aaccacactg ggaaattgca gaaaatcttg atattttaga ttttgaacgt ggcgcaaaag
     3241 tagccggtag ccgttttgtc tattacaaag gattaggtgc tcgattagaa cgtgctgtct
     3301 acaacttcat gcttgatcag catatttacg aacacggcta tactgaaatg atcactcctt
     3361 atatcgtcaa cagtaaagcg atgtttggta cgggacaatt tccaaaattc aaagaagatg
     3421 ttttccaatt ggagaatact gatctaacat taatcccaac agctgaagta ccattaacta
     3481 actattataa tgatgaaatt ttagatggtg cagatttacc tatttatttc actgcactaa
     3541 gccctgcttt tcgttctgaa gccggaagtg ctggtcggga tacacgagga ctgattcgtc
     3601 ttcaccaatt caataaagta gaaatggtca aattttcgga tgtagagcat tcttacgaag
     3661 aattggaaaa aatgacagct gatgcagaag atatcttgaa aaaattgcat ttgccttatc
     3721 gtgtgatggc cttatcaact ggagacatgg gcttttctgc agctaaaact tatgacttag
     3781 aagtatggat acctgcacaa gatacttatc gtgaaatcag ttcttgttct aactgtgaag
     3841 atttccaagc acgccgcgca atgatccgtt atcgcgataa tgatggaaaa atccactata
     3901 ctcatactct gaatggttca ggacttgcag ttggccgtac agtagctgcc attttggaaa
     3961 actaccaaaa tgaagatggt tctgtcacag ttccagaagc gctcgttcct tatatgggga
     4021 atctgaaagt tattaaataa agaggctgtg aaaaagccgc ttagtttcga gtattaagaa
     4081 aaattttgtg aaaatggctt tccacatttt tgcataaatt ggacttaata ccgagaaact
     4141 ggcttttgaa caccatttat cgagaggttg tgaaatcagc gaattaacct gagtattaga
     4201 gaaaaaaatg gaaaaatagt ccctcatatt ttaccgtttg ttgaactaat accgagggtc
     4261 agctgattga acaccgttta gtggagaggt cgtaagccta ccccccagct cctagttaca
     4321 aggacaaatt caaaaaacag ctcttcatat tttatgaatg ttgtacttgt gattcggagg
     4381 tggcaaggga acactgttta ttcaaaaaga ggctgggaca gaagcgttta actccaagaa
     4441 ataagaagaa attcacgaaa attgcttttc aaatttttgt gaatttcttc ttatttccga
     4501 aggagttgct tctacttccg ccgtttatac gtgtttagag cgtgagacaa aagtgttctt
     4561 tacttttgtc ccacgctctt taatgttttt aagattcaac tgaatagttt ggtgcttctt
     4621 ttgtgatttg tacatcatga gggtgtgatt cttttaatcc actgccgctc atttggataa
     4681 attgcgcttc atcacgtaat tgctgtagat tggctgcccc aacataaccc attcctgaac
     4741 gcaaaccgcc gatcatttgg aaaataatat ctgcaacact tcctttataa gcaacccgac
     4801 cttcgattcc ttctggtact aatttatttg cttcattgac actaccttgg aagtaacggt
     4861 cttttgaacc tttttccatc gcgcctaatg agcccatacc tcggtatgtt ttgaatcgac
     4921 gtccttggaa gatttcgaat tcacctggtg attcatctgt ccctgccaac atacttccta
     4981 gcatcactgc atgtccgccg gcagctaatg ctttgacgat gtcaccagaa tatttgatcc
     5041 ctccgtctgc aataatcgct ttgccatatt gacgagcaac tgatgctgca tcataaatag
     5101 ctgtgagctg aggtacacct acaccggcta ccacacgtgt cgtacaaatc gatcctggtc
     5161 cgataccaac ttttacgaca tctacacctg catcatataa agcttttgtc gcttcagccg
     5221 tcgcaacgtt tcctgcaatc aatgttgcat ctgcaaaagt tgaacggatt tcttgaattt
     5281 ttcggatcac acctgcacta tgtccatgag ctgtatcgat gatgattgca tctgcccctg
     5341 cttctaataa agcattcgca cgctcaaatg tatcgcttgt tacaccaacg gctgctgcta
     5401 caagcaatcg accatgttca tcttttgctg catttggaaa ttcgatcact ttctcgatgt
     5461 ctttgatcgt gatcaatccg cttaaacgac cttcgttatc tacgattggt aatttttcga
     5521 ttttatgttt ttgcaaaatc ttttctgcat cttttagaga ggtacctact ggggcagtca
     5581 ctaagttgtc ttttgtcatc acatcagcaa tcggcatgtg ataatctgtt acaaaacgca
     5641 tgtcgcggtt tgtaattatc cctaccaatt ttctgttttc aagtgtttca acgattggca
     5701 caccactgat acgatatttg ctcatcaatt cttctgcgtc tgctacaaga tgctgcggcg
     5761 ttaagaagaa cggatcaatg attacgccac tttcagaacg tttgactttt cttacttcat
     5821 ccgcttgctg gctgatcgtc atgtttttat ggatcacacc tagtccgcct tgtcttgcca
     5881 tagcaatggc catcttgctg tcggtaacag tatccatact tgcactgatg attggaatat
     5941 tcaacttaat atttttagct aattgtacgc tcatatccac ttcgtttggt aacacgtgac
     6001 tttctgctgg tatcaataag acatcatcaa aagtaaatcc ttttttcgtg aactttgttt
     6061 cccagttgga catttttagt accactcctc taatttagtt tatctattaa aataattgat
     6121 tttttcattt aagtcaatga tctacttgga atcaagttag ctttctcata gaataccaat
     6181 ataaagcgtt tacatctgtg tgtattaaaa gagattgtaa aaaagctgtc ctgcatcaag
     6241 taataagaac agccaatcaa aaacagcttc tcatgttttt gaattggttg ggtttattac
     6301 cgcagatgca aacttttgaa caccgtttag tggagaggct gtgaaaaagc tgcttagttt
     6361 cgagtagtaa gaaaaatttt gtgaaaatgg ctttccacat ttttgcataa attggactta
     6421 ataccgagaa actggctttt gaacaccgtt tatcgtaaaa agggactgtg acaagacttt
     6481 tgtcacagtc ccttactatt atttaactat ggataaacaa aatgaggttc tttactaccc
     6541 ctagatatct agcaaaatag ctgatctttt tgctagttta tcttcttggg acggataaac
     6601 ttccaataat cccgtatttt ttcttcaagt agtaacggat tgctaaagca gttgccccga
     6661 taatgataac tactactgga tctaatactg gattgataac tggtggcaat agtgttgtcg
     6721 cagaaaacag tacgacccaa agaagtgtcg ttccacctag gataagcaat gtcttaccca
     6781 ttcctggttt cttgcttcga tctgctccgg gatattcata ttgatagatg tatttgtaca
     6841 tcatataaaa gacccagcca ccgattgcag aacctagaac gagtgtagaa aagccataag
     6901 ctggcgttgt tccacgtgaa aacaatccgg taatcgcaat catgatactt aatagaccaa
     6961 gcaacagcaa cgtattatct aaccacatca ataaaggggt ggatgaattt tttacttctg
     7021 ctggcttatt gatgattgct tccgttcttt cagagactgt cccaaacaat tgacgggctg
     7081 ttcttccgcc tttttgttct gcaactaaag taggcagaat gtcatgaagg gcttttactt
     7141 tttcttcttc agacaaattc gctgcttcta aagatttttt caaatcaaaa atgtactgtt
     7201 gatttctttt ggttaatttt gtttctaaac tattgttttc ttttacgatt gctcgtaatt
     7261 gttctggttc cattatctaa tagtcctcct tagccgttcc ttttctcaac ggtcgtcaca
     7321 aaagacattc taccatattc tacagctagt ttgatagccc ttttacacat taaagcggaa
     7381 taacattacg tcgccgtctt gtacgacata atcttttcct tctaatcgaa cacgtccagc
     7441 ttcttttgct gcatgcatgt ttccgtaatg atccaagtct tcaaaagaga cagtttctgc
     7501 acggataaat ccgcgttcga aatctgaatg gatgattcct gctgcttgtg gtgctttgat
     7561 tccttttttg aatgtccaag cacgtacttc ttgttcccca gcagtaaagt aagtagctaa
     7621 gcctaacaaa tcataagcag cacggatcaa ctgatccaaa cctgattctt cgattcctaa
     7681 agcttctaaa aattccgctt tgtcttcttc atctaattct gcgatttctt cttctgcacg
     7741 agcactgacc acgatcactt ctgcattttc ttctgcagca aagttgcgca cttcttgtac
     7801 ataatgattc gcgtctgcat ctgctacgtc atcttctgag acattggcta cataaagaat
     7861 tggttttgtc gtcaataaaa atagtgattt aacgattttt tgttcttctt cagtaaattc
     7921 gatcgttcgg gcagattttc cttcttccag tacaggtttg attttatcca gtacagctag
     7981 ttctgccact gcatctttat ctttggtttt agcaactttt gctacacgag tatagcgttt
     8041 gttgatagat tctaagtctg ctaacactag ttccaagttg atcgtatcaa tatcttctag
     8101 tggatcaaca cgtccttcta cgtgagtaat attatcatca tcaaaacagc gaacaacgtg
     8161 acaaatagcg tctacttggc ggatatggct taagaattga tttcccaaac cttctccttt
     8221 acttgcgcct tttacgattc cagcaatatc tgtaaattca aaagtcgtcg gaacagtttt
     8281 tttcggatgt acaagttctg ttaagcgttg caaacgccag tcaggtactt ctaccatccc
     8341 tacgttgggg tcgatcgtcg caaagggata gtttgctgct tctgctcctg cttttgtgat
     8401 cgcattaaac aaagttgatt ttcctacgtt gggcaaccca acaattccag cagtcaatgc
     8461 cataaattta ttcactcttt ctctgcattt ttttcaatta ctttttttaa tttcttttca
     8521 aaatctcgac gggtcatcat gacgatatgt ccgcaattca tacatctgat tttgatatct
     8581 gcgcccattc gaatgacttc ccagcgattc gtctggcaag cgtgaggttt tttcatttca
     8641 acgatatcgt gcaagtcgta cataaaaata gcctcctttt tgtttattct tcatcaaatt
     8701 gaatattcaa gatatcaaga attcgagtca aatctttttg agaaagatat tcaatctcga
     8761 tcttaccttt cccatttttt tcttggatag ctacacttgt accaaattta tccatcaaac
     8821 gatcttcgct ttctcggata taatatggtt tttcctttgc tagccttggg atttttttct
     8881 tttcttttcc atcattttga tttaactcag aaacaagctg ttccagttgg cggacagtta
     8941 aattttcagt tactgcacga ttggctaatt tcaagatcaa tgttttattt tttaaaccta
     9001 acagcgtacg ggcttgtccc atagataaac gctgatcttg taccatttcc ttgacaagat
     9061 ccggtaaaga aagcaagcgc aaataattgg cgatataagg tctgctcttt cctaaacgac
     9121 tagctacttc tgcttgtgtt agtttcaggt ttttcatcag catctcatat gcttctgctt
     9181 cttctaacgg attcagatct tctcgctgca agttttccag cactgctact tgcatcatcg
     9241 cttcttcgtc aaagtctcta acgatagcag ggatcgtttc tttttcagct agtttggacg
     9301 ctcgaaaacg tcgctcccct gcaataatct catatccttt tactgcggaa cggcgtacga
     9361 tgatgggttg aaagacacct gattgttcaa tagaattagc tagttcctgc aaagatactt
     9421 cttcaaatgt tttacggggc tgatacggat ttggtcgcag ctcattcaat ggtagctgga
     9481 caacggtatc atcttttaca tccaccgtct ctaagttttc taaatcttga aacagtgcat
     9541 cgattcctcg gcctaatcct ttacttttct tcacgactta ccacttcctt tgccaatgct
     9601 tggtagactt cagctcctcg agaacgtgga tcgtagtcga tgatcggttt tccatgacta
     9661 ggtgcttctg ataaacgaat atttcttgga atgatcgttt cgtaaacttt ttcgcggaag
     9721 tatttacgta cttcttctac gacttcattt cccagatttg ttcgtgcatc atacattgtc
     9781 agtaagactc cctcgatctc taattctgga ttaaagtgtt tttggactaa acgaaccgta
     9841 ttcagtaatt ggcttaatcc ttccaatgcg taatactcac actgaacagg tatcaaaatc
     9901 gaatcacttg ctgtaaatga attgattgtc agatggccaa gagaaggcgg gcaatcgatc
     9961 aaaatataat catactgact gcttacttct gctaaagatc cttttaatct tgattctctt
    10021 gccatcattg acgtcaattc gatctctgct cctgctaatt ggagagtcgc aggcacaata
    10081 ctcaaatttt cgtgttcagt gatcaaagtt gcctcatcaa ttggcaattc attgactaga
    10141 acatcataga tgtctcttgt cacatcaggt tttctgatcc cgacaccact ggtagcattt
    10201 ccttgtgcat ccatatccac tagcaatact tttttgccaa ggctagcaag acaagcacct
    10261 agattcaccg tcgtcgttgt tttgccgacg ccaccttttt ggttcgcaac agatattatt
    10321 tgtgccatct cttctcctcc tatttgattg gctgcttatt aggcagtccg ggctttcttg
    10381 ggtatttctt tggggttggt ttcttttttt gaataacgat gatatgccgt tgatcagaga
    10441 cattcggcaa ggtaaccgcc tcttctttga ggaatttacc acctaataaa gcaatcgctt
    10501 gttttgcttc tgtcaattcc tcttcacttt ttgctgcttt caatgcataa aaatagcctt
    10561 cttgtttagc caagggcaaa cacaattccg ctaacacatt caaacgagca accgcacgag
    10621 cagtgacaag gtcaaatgat gcacgaaagt gaggattttg cccaaatgtt tctgcccggt
    10681 catgatataa ggaagcatcg attcctaata atcgggttaa ctcagataag aaggttattc
    10741 gtttattcag agaatcaacg atcgttatct gcagttctgg aaaggcaatt tttaaaggta
    10801 tgctaggaaa ccctgccccc gaaccaacat cgcataaaga taaaggttgc gtaaagtcta
    10861 cttcaaatgc taatgtaagt gaatcgtaaa aatgcttcag atatacgtct ttttcatccg
    10921 taatagctgt aaggttcatc ttttcgttcc attcgactaa tgtccgataa taaatagcga
    10981 attgattcat ttgatgatcg gtaagctcta tccctttttc tgccaaggat tggcgaaatt
    11041 cttctggtat cataaatatt cctttcattg tgaaacagca attgtttcac agattctctc
    11101 cctactttaa cgcaaaatct ctagacatgc aatccttcca tatggattct taaaaatttg
    11161 aaaagtaaga aaagccgata gactttttct ttctagtatg actcataaaa tatacacaga
    11221 agagagaact agctttgagc aatttctgca aaaactagtt ctctcttcta tttattatta
    11281 cgtattacgc tggttcactg actttcgcaa tcttcccttg ttcgatatag accattagga
    11341 tacttaggtc tgcagggttt acgccactga ttcggctagc ttgggcaatt gtttctggtt
    11401 ggattttctg caatttttgt tttgcttctg ttgctaatcc gttgattgct gcgtagtcga
    11461 tgttttctgg aatctttttc gcttccatgc gttttaattt ttctactttt tccatggctt
    11521 ttttgatgta gccttcatat ttgatttgga tttctacttg ttcgatttct tttcgtgtca
    11581 attcttcatt ttctggaata aaccgtagaa gttctgcata agtaatctca ggacgtctta
    11641 aaaagtcgct tgctagtaca ccatctttta atggtgccgc attaatcgtt gctaaaaagt
    11701 cttggacttc ttctgttggt ttgattcgta cattcatcaa acgtttgatt tcttgttcaa
    11761 ctgcttcttt tttcttcaaa taattcttgt attgatcttc ttttactaag cctacacggt
    11821 gacccatttc tgttaatcgc aaatctgcat tatcatgacg taaaagcaga cggtattcag
    11881 cacgtgaagt cagcaaacga taaggttcgt tcgttccttt tgttaccaaa tcatcgatca
    11941 tgacaccgat gtaaccgtca cttcgtttga tcactaaagg ttcttttccc tgaactttca
    12001 aagctgcatt gataccggca atcagccctt gtccagccgc ttcttcataa ccgcttgtac
    12061 catttgtttg tccagctgta taaagatttt caacgacttt agtttctaat gtcggacgga
    12121 gctggtgtgg ctctactacg tcatattcga tagcatatcc tgtacgcatc atttctactt
    12181 tttctaatcc agcaatagaa tgaagcatgt tgacttgaac atcctctggt aaagaagtag
    12241 ataaaccttg aacatagact tcttccgtat ttaagccttc tggttccaaa aataattgat
    12301 gacgtggttt gtctgcaaaa cgcacgatct tatcttcgat ggatggacaa tagcgagcgc
    12361 ctaccccttc aacgatccct gtaaacattg gggcacgatg taagttgtct cgaataattt
    12421 ggtgagtcgt ctcacctgta taggtcagcc agcaagattc ctgatctagt ttataggcac
    12481 tatctggtgt gctgaagcta aaatgattcg gctctttgtc accaggctgc tcttctgtaa
    12541 cagaatagtc gatcgtactt gattttactc gaggcggtgt tcctgttttg aaccgttcga
    12601 tagcaaagcc aagttctttt agatgattcg ctagtccaat agaaggttga gagttattcg
    12661 gacctgatga atatttcaat tcaccgataa tgatttctcc gcgaagtgct gttccggctg
    12721 taataacaac tgctttggcc cggtagctcg ctcctgtgga cgtcactact ccatgacaaa
    12781 caccatcttc gacgatcagt tcttcgacga ttccttgtct tagcgtcaaa tttggttctt
    12841 tttcgatcgt atgtttcatt tctgttgaat aagcatgttt gtctgcttgt gctcgcaatg
    12901 ctcggacagc tgggcctttt cctgtgttca acatacgcat ttggatatag gttttatcga
    12961 tattcttacc catttctccg cctaacgcat cgatttctcg aacgacaacg cctttagctg
    13021 gtccgcctac agaaggatta catggcatga atgctaccat gtccaaattt attgtcagta
    13081 ataatgtttt tgatcccata cgtgcagcag caagtgcagc ttctgaaccg gcgtgtcctg
    13141 cgccaacaac gatcacgtca tacgcatctg cttcataatg ttccaatcgt ttgttcctcc
    13201 ttttattttc ctaaacaaaa ttgactgaat aattgagtga ttagctcatc ttgtacactg
    13261 tcgccgacaa cttctcctag atagtcccag caacgcgtca tatctatttg aacgagatcc
    13321 acaggcattc ctgaatcaat acctgcaatg acttcttcaa gtgagaggga agctttttct
    13381 aacaacgcga tatggcgggt attagaaaca taagtagcgt ctctttctcc tgtttctccg
    13441 ctgaagaata aatcagaaat agctgattcc aaacgatcta gtccgtcgtt tttagctacg
    13501 gaaattgaaa aaactggttc attttcgatc aatttcttca atttttcttg ttccagctgt
    13561 gctggcaaat ctgttttatt tagaagaatg atccgtttca atccacttgt cgcttccaat
    13621 aattgttcat cttctgctgt cagtggttcg ctttggttta gaacaagtaa gatcaagtct
    13681 gcttctgcta atgcttttcg gcttctttcg accccgatcc gttccaccac atcttctgtt
    13741 tcccgaattc cagctgtatc gattagcttg agcggtaccc cccgaacatt gacatactct
    13801 tcgattacat ctcgagtcgt tcctgcaata tccgtaacga ttgctttttc ttctcttaac
    13861 aaatggttta acaaacttga tttgccgaca tttggccggc cgatgattgc cgtacttaac
    13921 ccttcccgca gaaccttccc ttgcttggat gtagcaagta gcgcttggat tctttgttgg
    13981 atcatctgcg ctttttcaag caataacttc gtagtcaatt cttcgacatc atcatattct
    14041 ggataatcaa tatttacttc tacttgtgct aatgtctcta aaatctcttg tctcaatgag
    14101 cggatcaaag cagacagatt gccgtctaac tgattaagag ctagtcccat tgctttgtct
    14161 gtttttgccc gaatcaaatc catcacagct tctgcctgtg aaaggtcaac acgaccattc
    14221 aagaatgctc gttttgtgaa ttcgcctggc tcagctaatc ttgcaccttc tcttaacaat
    14281 agctgcaaaa tttgattgac tacaacgatc ccaccgtgac aattgatttc tactacatct
    14341 tcccgcgtaa atgtctttgg tgctctcatc acggagacca tgacttcatc gacaagctga
    14401 ttgctcttgg gatcaacgat atgtccataa tggatcgtat gacttggtac ttctgataat
    14461 cgtttgtttc cagattgata aactttatct gctagttgca cagcttgatc gccacttaaa
    14521 cgaacgatac tgattgcacc ttctccaggt ggggtagaaa ttgccgcaat cgtatcaaat
    14581 tctaaagtaa tttcagccat tttttcactt cctttttcat tttgcgcaca aaaaaagtgc
    14641 ccactccacc ctttatgcac aataaacggt gaacttcgca ctttgactgc ttgttcttga
    14701 ttaaattctg gtcatagatt atcacacttg ctataaggaa tcaagtgttt aaaacaatta
    14761 gatgaagttg agcctgttct gcttccatta ccttatattt aattgtcctt ggatgtctct
    14821 ttgcgttctt tggtttattc gaagagaaga tactgtataa acaaggcttt atctttctta
    14881 aaaaaaacgg tacactaaat ggtagcgcta tctaaactat acacttttga aaggagaaaa
    14941 tatgtgagcc cgttcagatc tgctgcattg gaagaagaaa gtgaccctcg gatcaacgat
    15001 gtcgttttat ctacagggaa tatcaaccag aaatatatcg tccgcgatat cgtttttgtt
    15061 gtggaatgct tagaagctga tttgtttgac ccatcttttc ccaaagatga ccttttctta
    15121 acaacgaaga ggaaattaaa gacgaaggta cttgaatatg gtgcgaatgc agtaatcaac
    15181 tgtcattttg agtatcagca aaaaaaacgc gacggaaagt attttctgga actttttgct
    15241 tatggaacag tgatccaatt tatccaaaca acgattggtt aaatgaaaca gacaaaaaaa
    15301 gcggatcaaa actgaagaca gtttcgatcc gcttttttct atcaaagtta gtgactactt
    15361 catcgtatac tctgataaga atgatttcta gtaaaatata cttggtttga aaaactttgt
    15421 caacgtgatt tattcaaaaa gtaatggaat caataatatt ttttagcagg ttctactact
    15481 aaataacgat aaggttcctc accttccgaa tgtgttttta catgttcatc tttgcttaat
    15541 gcagcatgga tttgtttacg ttcaaatgca ggcattggtt ctaagaaaac aggctgccct
    15601 gtccgtttta ctttttcagc cgtgcgatca gctaaacgct gaatgatctc ttggcgcttt
    15661 tcacggtaat tgcctacatt gactactaca gacagcttat ttcttgctaa acgatggatg
    15721 aagacttgtg ccagatattg caatgcattc agtgtttttc catgtttccc aatcagtatg
    15781 ccttgctttt gtgtttctaa atggaaaaca accatattat ttgattctct ttccattttg
    15841 acaagagctg gagcatcaag ctgttttgaa atttcagtaa gataaactgc caattccgtt
    15901 aaagctgctt catcacctag ctcacttact tcttctgttt tttcttcaag aatcgtttcg
    15961 ttgactacct cgatctcagc tgttggttct tcttccaaaa tttcttctac agtctgttct
    16021 actgtttcag aaactttttc gctgatactt ggctggatcg aaagccgtgc attctttcga
    16081 cccattccta ggaaaccttt ttttccttct tccagtattt cgatttcgac ttggtctttg
    16141 gccaaaccca aatcagccag acctagttgg acagcttcgt ctattgttgc agcttcataa
    16201 atcggcatta gcattacctc ccctattatt tccgtttttt cttaggattc attgctttct
    16261 taagagcacg ttctctttcg cggattctcc gtgcttcttc ttcacgctct tttcgaattt
    16321 tgaaagggtt gttgatcagc agcgtttgta caacttggaa ggcattggaa actacccagt
    16381 ataatgaaag accgctggct aaattgacac ccatcactaa aatcattaca ggcatcacga
    16441 aattcatgat cttcattgat gcattcgatt caatttgact catgctagat aaatacgtac
    16501 ttgcaaaagt aaagattgct gctaaaatcg gcaaaataaa tgttggatcc gcgttcccta
    16561 agttcaacca taagaaatgc ccttgtttca actctggtac acgtgaaata gattgccata
    16621 acgccatcaa gattggcatt tgtactaata aaggaagaca accagcatat ggattgacgc
    16681 cattttctgc atataaacgc tgctgctctt ctcttaactt actttgtgtt tccggatctc
    16741 ttgaactata ttgttgctgc agtgctttta atttcggttg taattcttgc gttttacgca
    16801 tgctctttgt ttggaaatgc atcaacggca ataggatcac gcggatgatc agtgtaaata
    16861 aaatgatccc tatccctgca ttaccaaatg acaacgcctt gatcgcctca gcaaagtaat
    16921 aaacaatata acgatcccaa attcctgtac tctgtgcgct gacttcccca gttccgcaac
    16981 cggataagac gatgaccaaa ctaacgatac cggccatcaa aagtaaacgt ttgtatttct
    17041 tcacttactc ttttcctctc tgtcgattat ttttgcaagt tttaagacgt ggactaaatt
    17101 ggagcgaacc tcatcataag tcaacccctt cacacttggt ctagcaatca caataaaatc
    17161 caactccgga tcaatttctt cttttataga ataaactgct gctcggattt ttcgtttgac
    17221 ttcattgcgg tttaccgcgt tgccgacctt ttttcctaca gataaaccaa ctcgaaaatg
    17281 aggctgtccc ggtttttcca aacggtaaac gacgaatttg cggttagcaa aagaatctcc
    17341 cgtatggaac acggcttgaa actctcgttc tttttttact cgatacgctt ttctcattag
    17401 ttttctttcc ttttctatct ctcacttacg ctcataatca taccataatt acgattgtcc
    17461 tttcatcatt tccctaaaaa agagtataaa aaaaaccact gaaaccccag tggcctaagc
    17521 tgaaagaact tttcttcctt tgcgacgacg gctagctaac acacgacgtc catttttagt
    17581 actcatacgt ttacggaatc cgtgaacttt ttgacgttta cgtttatttg gttggtatgt
    17641 tcttttcata tattccacct ccaaaatgtt cttatctatt ttataaacac agacatactt
    17701 tgatagtata acgacaaagt agtgattttg tcaatataaa atagaagatc gattgttaaa
    17761 acttatccac aagattattt ttttctatgg gagtcctatg tggaaaaagt tatgcacagg
    17821 gattatccac agataataaa tggctggttt tacacagaaa acacacgtgt aaaaaaagta
    17881 atccacaatc aggtgatttc ctgtgtattc cgtctcctaa ctattggtat atctatattt
    17941 tttatccaca gatgcaagag gaaatctatt gatttttacg agttttccac ctgtgcatta
    18001 gtggtgtgga aaactttttt ttgacaactg tgtttttctc ttttttcttt ttgtcgattg
    18061 tgtggataat tgtaattaaa aaattttttt cttcggtttc tgtggaaaac tattgaaaaa
    18121 aatgctaaat tagtactagt tattcacttt ttaatgaagg aggaggcctt atatggtatc
    18181 cctcgatgct ttatggaatg aattaaaagc aacataccaa aaggatttat cgcctgctag
    18241 ctataataca tggatcgaaa cagcgaaccc tcgaaccctt gatcaaaacc agctcgttgt
    18301 tgaggttcct agcaagattc ataaagaata ttgggaaaaa aacctggcga caaaaatcgt
    18361 tgaagtcggt tatatgttat caggaaatga gattatccct cgctttatta ctggcgaaga
    18421 agcagagcaa gaagaagtta tagaagaaaa aaatccaaaa gttgtggcac ctagtccgct
    18481 aaaaaaagcc atgctgaacc ctaaatatac ctttgatacg tttgtcattg gtaaaggaaa
    18541 ccagatggct catgcagcag cgctcgttgt agcagaagat ccaggttcta tttataaccc
    18601 gctcttcttt tatggaggcg tgggacttgg taagactcac ttgatgcatg caattggtca
    18661 tcaaatgctg caaagtcagc ctaatgccaa agtaaaatat gtaagcagtg aaacttttgc
    18721 taatgatttc atcaattcga tccaaaacaa aacagcagaa gagttccgtc aagaatatcg
    18781 aaatgttgat ttactgctag tggatgacat tcaatttttt gcagaaaaag aagctacgca
    18841 agaagagttt ttccatactt tcaatgcctt gtacaatgaa gggaaacaaa tcgtactaac
    18901 cagtgatcgg ttgccaaacg agattccgaa actgcaagaa cgcctcgttt ctcgctttgc
    18961 atgggggctg tctgttgata ttacaccgcc ggatcttgaa acaagaacag cgattttacg
    19021 taaaaaagcg gcggctgaac gtctagagat cccagatgac acactaagct acatcgcagg
    19081 acaaattgat tctaacattc gtgaattaga aggtgcgctt gttcgagtgc aagcttttgc
    19141 tgcgatgaat agtgaagata tttcgactag tctagctgca gacgcactga aaacgttaaa
    19201 atcaggaaaa ggacatcctc aattgtcaat cctgcagatc caagaagaag tggcaaagta
    19261 ttatcacatc caattgaaag atatcaaagg aaagaaacgc gtcaaatcta ttgttgttcc
    19321 tagacaaatc gctatgtatt tggcacgtga gctcacagat aattctttac cgaaaatcgg
    19381 agctgaattc ggtggcaagg atcatacaac ggttatccat gctcatgaaa aaatccagca
    19441 gctgatggat tctagtgtca gtatgcaaaa tgaagtatca gaaatcaaaa actttttact
    19501 aaattaattt gtcgattcta tcaactgaaa atagcatgtg gataaaagaa aaaaacgttc
    19561 aaaagttatg cacacttttt ccacagctgt tttttcgttt ctctcttacg ttttttgagt
    19621 tttccacaga atcaacatgc cctattactt ttattattct ttttaactaa taataaataa
    19681 acaaacattc aaaggagata catcatgaaa gttactttaa accgagctag ctttatgcag
    19741 gaattgcaaa ctgttcaacg agctatttca agcaaaacca cgatccctat tttgacaggt
    19801 gtaaaaatca cactgacaca agaaggtttg actttgacgg ggagcaacgc tgatatatca
    19861 attgaaactt ttttgtctgt tgaaaacgaa aaagcaaata tgcaaatcga atctactggt
    19921 tccattgttt tacaagcacg tttctttagc gaaatcattc ggagacttcc tgaagaaaca
    19981 tttactttag aagttttaga aaataaacaa gtagcgatta cttctggaaa agcgaatttt
    20041 atcgtaaatg gattagatgc agataactat cctcatcttc ctgttgtcga aagccataac
    20101 cagatgaaat tacctgtaca cgtattgact aaactaatca acgaaacagt ttttgctgtc
    20161 tcacaacatg agagtcgtcc aatcttgaca ggtgtgcatt tcattttatc tgataattct
    20221 ttattggctg tagctactga ttctcaccgt ctaagtcaac gcgtgattcc agtagaacaa
    20281 gcggctgatc attttgatat tgttattcct ggaaaaagtt tgatcgaatt atctcgctca
    20341 ttaacaaatg aagaagaaat cgtcgaaatc agcattatgg aaaaccaagt gttgttcaaa
    20401 acagaaacga tgtatttcta ttcccgtttg ctagaaggaa actatcctga taccaatcgt
    20461 ttgattcctt caagttttaa tacagaggtt gaattttctg ttcctagctt tttagcggcg
    20521 atcgaacggg cttctttact ttctcatgaa ggccgtaaca acatcgttcg tttatctatt
    20581 cgtccagatg cggttgtttt atacggaaat tcgccagaaa tcgggaaagt agaagaaagc
    20641 ttgagttata cagcaagcag tggcgatcca ttagatattt ctttcaatcc ggattatatg
    20701 aaagcagcgt tgcgtgcatt tggagatatg agcatcaaag tgaaatttat ctctgctatt
    20761 cgtccattta cattggaacc aacggaagat ggcgttcaat ttattcagct gattactcct
    20821 gtacgtacaa attaacaatg attttcattg ttcttgaaaa tttaattgaa aagaaataga
    20881 aaaaataaaa ttttaaacag aaggccctaa aatctctttt aaggctttct gtttattttt
    20941 gtttaaatca ccttttttag attaaatcgt cttatatgga aaaatatatg gataaatttg
    21001 ttttattgcg aaaaaaaagg tataatagag tatactttta ataatgaaaa tgagggatgg
    21061 gcattgaaac aacaagtcat tctaaatacg gaattcatga cgttgggcca aatgttgaaa
    21121 gaagtcacag ttatcggtag tggcggacaa gcaaaatggt atttggcaga aaacactgtg
    21181 ttagtcgatg gcgaaccaga aaatcgtcgt ggacgcaaac tttatcccgg catgatggtt
    21241 gaagttccag aagtaggaac tttttttatg gtaaaaaaag gaaacgacga taatgaggct
    21301 gaataagctg tatttaaaaa attatcgaaa ttacgaagag ctgaacatcg aattttccaa
    21361 gaacctcgtc atctttttag gagaaaatgc gcaaggaaaa acgaatcttt tggaaagtat
    21421 ctacgtatta gctatgacgc gaagtcatcg gacaagtagt gagcaggaat tgattggctg
    21481 gactgacgat caggcgatga ttcaaggaga gatcacaaaa ggttcatcca ctcttccatt
    21541 agaaatctta ttatctaaaa aaggccgaaa aaccaagatc aaccatatcg aacaaaaaaa
    21601 gttaagtact tacgtgggac aaatgaatgt cattttattt gcaccagaag atctttcttt
    21661 agtaaaaggc agcccgcaga tcaggcggaa gtttttagat atggaattag gccagatcaa
    21721 tccaatctat ctttatgatc ttgtccaata ccaagcaatt ttgaaacaaa gaaaccagta
    21781 tttaaagcaa ttgaatgaaa aaaaacaaac tgatttgctt tatttggata ttttgtccga
    21841 acaactagca gcgtttggca gcaaagtatt gaaagcaaga gcacagttcg tcaagcgatt
    21901 ggagttttgg gctaattctt tgcatcagca aatcacccat caaaaagagc agctggaaat
    21961 cgagtatctc accgcagtcg attctttaga aacacatacg caagagcaaa tccaagaaca
    22021 atttctcgca cttttgaacc aaaataaaaa gaaagacctt tttcggggaa caacgacagt
    22081 tggtcctcat cgtgacgatc tttccttttt tattaatcag aaaaatgtgc agacttatgg
    22141 atcgcaagga cagcaaagaa caactgcact aagtgtcaaa ttagcagaaa tcgatttgat
    22201 taaagaagag acgggggaat atccaatcct tttgttagat gatgtgatga gcgagctgga
    22261 tgatagtcgt caactccatc tgctagaaac aatcgaagga aaagttcaaa cgttcttaac
    22321 aacaacgaca cttgaccatg taaaaaataa aatgactgtt gaacctgaga ttttttatgt
    22381 tcaacaaggg aaactaaaag gagaagaaac tgaatgacag aagaaagaag tttagtagaa
    22441 cgcgctaaag agtatgatgc cagtcagatt caagtacttg aaggacttga agccgttcgt
    22501 aaacgacctg gcatgtatat cggttcgact agttctgagg gtctgcatca ccttgtttgg
    22561 gaaattgtcg ataattcgat cgatgaagta ttagcaggtt ttgcaacgaa aatccatgtg
    22621 attattgaaa aagacaacag tatcaccgtt attgacgacg gtcgggggat acctgtagat
    22681 atccaggcaa aaactggacg tcctgcagtt gaaacggtct ttactgtttt acatgctgga
    22741 ggaaaattcg gcggtggtgg gtacaaagtt tctggtggac ttcacggagt aggatcttct
    22801 gttgttaacg cgctttctac acagcttgat gtcaaagtat acaaagaagg aaatgtgtac
    22861 tatcaagaat atcgtcgtgg agctgtagtg gacgacttaa agattatcga acaaacggat
    22921 cgccatggaa caacggttca ctttacgcca gaccctgaaa tttttacaga gacaactgag
    22981 tttgattttt caaaattggc tacccggatc cgtgaacttg ctttcttgaa ccgcgggatg
    23041 cgtatatcga ttgaagacaa acgagaagaa gaaccagtca tcaatgaata ccattatgac
    23101 ggcgggatta aaagttatgt cgaatacttg aatgcaaaca aaaccgtgat ttttccagaa
    23161 cctgtatatt tggaaggtga acagcaagat atcgcagttg aagtctctat gcaatataca
    23221 gacggctacc attccaatat catgagtttt gccaacaata tccatacgta tgaaggcgga
    23281 acacatgaat caggattcaa gactgcttta actcgtgtga taaatgatta tgcccgaaaa
    23341 caaaagctga tgaaagaaaa tgacgacaac ttgaccggtg aagacgtgcg agaaggattg
    23401 acagctgtta tttctatcaa gcatcctgac cctcaattcg aaggacaaac aaaaacaaaa
    23461 ttgggcaatt ccgaagtacg gacagtcact gatcggttat ttagcgaaca tttcatgaaa
    23521 ttcttgctgg aaaacccaag tgtgggccgt caaattgttg aaaaaggatt actagcttcc
    23581 agagctcgtc tagcagcgaa acgtgcgcgt gaagtaacga gacgtaaagg tgctttagag
    23641 attagtaatc tgccaggaaa attagcggac tgctctagca acgatcctga aaaatgcgaa
    23701 ttgttcatcg tcgaaggaga ttcggccggc ggatcagcta agcaaggtcg taatcgagag
    23761 tttcaagcca tcttgcctat tcgtgggaaa atcttgaatg ttgaaaaagc aagcatggac
    23821 aagatcttgg caaatgaaga gatccggtct ttatttactg ctatgggtac agggtttgga
    23881 gaagattttg atgtatcgaa agctcgctac cacaaattag ttatcatgac tgatgccgat
    23941 gtcgacggcg cgcatatccg tacattgctg ctgactcttt tttatcgtta catgcgtcct
    24001 attgttgaag ctggatacgt ctatattgct cagccacctt tatacggggt aaaacaaggg
    24061 aagaatatta cgtatgtaca accaggaaaa aatgcagaag aagagttgaa acaagtcgtt
    24121 gcttcacttc ctgcctcacc aaaaccaagc gttcagcgtt ataaaggact tggagaaatg
    24181 gatgatcatc aactatggga aacaactatg gacccaagca atcggatgat ggcccgcgtc
    24241 agtgtggacg atgctattgc agcagatcag atatttgaaa tgttgatggg ggatcgagta
    24301 gaaccccgtc gtgcattcat cgaggaaaat gcacactatg tgaagaactt agatatttaa
    24361 tcatgaagga ggaaaaagaa tgagtgaaga aatcagagaa aacatccatg atgtcaatct
    24421 aaccagcgaa atgaaagact ccttcatcga ttatgcgatg agtgttattg tcgcacgtgc
    24481 acttcctgat gtcagagatg gtctgaaacc cgttcatcgc cgtattttat acggcatgaa
    24541 cgaattaggt gtaacaccgg ataaagccca taaaaaatct gccagaatcg tcggagatgt
    24601 catgggtaaa taccatcctc atggagacta tgcgatctat gagtcaatgg tacggatggc
    24661 acagccattc agctaccgtt atatgctagt ggatggtcat ggaaactttg gttctgttga
    24721 cggtgacggt gccgccgcta tgcgttatac cgaagcacgg atgagcaaaa tcgctacaga
    24781 aatgctgcgt gatatcaata agaacactgt tgatttccaa agcaactatg atgatacaga
    24841 aaaagaacca gttgtactac ctgctcgctt cccgaatctt ttagtgaacg gaacaacggg
    24901 gatcgccgta ggtatggcca cgaatatccc acctcataac ttgtctgagg tagtagcggc
    24961 tatcgatttg ctgatggata atcctgatgt gacgaccaat gaattgatgg aagtattacc
    25021 tggaccagat tttccaacag gtggtttggt tatgggaaaa tcaggaatcc gaagagcgta
    25081 tgaaacaggt aagggttcta ttaccgtacg tgcaaaagtt gagattactg agatgccaaa
    25141 tggtaaagaa cggatcatcg tgacagaatt gccttatatg gtcaataaag caaaattgat
    25201 cgaacggatt tctgaactgc acagagacaa gcgtatcgaa gggatcacag atttgcggga
    25261 cgaatcttcc cgtgaaggta tgcggatcgt cattgacatc cgtcgtgacg ccagcgcatc
    25321 tgttatcttg aataacttat ataaattgac atccttgcaa aattcatttg gattcaatat
    25381 gttggcgatc gaaaaaggtg tgccgaaagt tttgagcttg aaacaaattc ttgaaaacta
    25441 tatcgaacat cagcgcgaag tcatcacaag acggacagtc tttgaaaaag aaaaagcaga
    25501 agcaagggca cacattttag aaggtttgcg tattgctttg gatcatatcg atgaaatcat
    25561 tgcgattatc cgcgggtcta aatcagatga cgaagcaaaa gcgacgatga tcgaacggtt
    25621 cgatttatcc gatcgccagt ctcaagctat tttagatatg cgtttacgcc gattgaccgg
    25681 tttggaacgg gaaaaaatcg aaaatgaata ccaagaactc ttaaaactga ttgaagattt
    25741 aactgacatt ctggcaagac cagaacgtgt tacagaaatc atcaagaatg aattagcaga
    25801 cttgaatcaa cgatttggtg ataaacgacg cacagaatta ctagtcggtg aggtcttaag
    25861 tctggaagat gaagatttaa tcgaagaaga agaaatcgtt attacattga caaacaatgg
    25921 ttacatcaaa cgtttggcaa ataatgaatt cagagctcaa cgaaggggtg gacgtggtgt
    25981 ccaaggaatg ggtatccaca atgacgactt cgtcaaaaat ctggtttctt gttctaccca
    26041 tgatacattg ttattcttta cgaataacgg aaaagtgtat cgggcaaaag gatacgaaat
    26101 tccagaatac gggcgcacag ccaaaggaat accaattatc aatttactag gtatcgattc
    26161 gagtgaaagc atccaggcaa tcattgcggt gacgggagaa gcagaagaag gccactatct
    26221 cttctttacg acgcgtcaag gtacagtaaa acgtacttct gtcactgctt ttgctaacat
    26281 ccgaagtaat ggtctgatcg caattggttt gaaagaagac gatgagctcg tcaatgtgct
    26341 actgacagat ggtcaatcta atatcattat tggaacacat aacggctact ctgtcacttt
    26401 caaagaagaa gcagtccgcg atatgggacg tacagcttcc ggggttagag gaatacgcct
    26461 gcgtgaggaa gattatgtcg ttggggcagc cttaatgaag gaagatcaag aagtattagt
    26521 gatcacagaa aaaggttacg gaaaacggac aaaagtatcg gaatatccag tgaaaggccg
    26581 cggaggtaaa gggatcaaaa cggcgaacat cactgaaaaa aatggtccac tagctggatt
    26641 gaccactgtt tctggagatg aagacatcat gctgattaca gataaaggtg tcattatccg
    26701 tttcaacgta tcgactgttt ctcaaactgg acgttcaaca ttaggcgtac gtttgatgaa
    26761 gatggaagct gatacgaaag ttgtcacgat ggcagcagtc gaaccagaag ctgcagaaca
    26821 aacagttgaa gaacaaggat cagaagaata gccatcaaga ctaattgtgt aagctagcaa
    26881 gaatgaccga ttaaaaaatc tggttattcc tgctggcttt tttgattagt tgaatttctc
    26941 ttaaaatatt cgaaactgtt cattctgtat tgcttttgac caaaatagag tgtataatca
    27001 gagcttgtga gtagtctaat taattagata actctccttg ctcttaggaa cctaagagcc
    27061 gaaagtccac agggaggtga atatcaatgg aaaacacgaa atatgaaatc atgtacatta
    27121 ttcgtccaaa cattgatgaa gaagcaaaaa ctgctttaat cgaacgtttc gatgcaatct
    27181 tgaaagataa cggagcagaa gttatcgaat caaaagattg ggaaaaacgc cgtttcgctt
    27241 atgaaatgaa cggttaccgt gaaggtatct atcacatcgt taaagtatct tctccatcat
    27301 cagcaaatgc tgtcaatgaa tttgaccgtc ttgctaaaat caacgacgat atcattcgtc
    27361 acatgattgt taaagaagaa gcttaattgt tgtttcatgt gaaacaatag aaaacgatga
    27421 gaggagatga ctattttgat taataatgtt gtattagttg gacgtctgac gaaagatcca
    27481 gatttgcgtt acacagcaag tggtacggca gtcgcaacat ttactttggc tgtgaatcgt
    27541 aattttacaa accaaagcgg caatcgcgag gctgatttta tcaactgtgt gatttggcgc
    27601 aaatcagcag aaactttagc aaactatgct cgtaaaggaa cacttttagg tgttactgga
    27661 cgtatccaaa ctcgttctta tgataatcag caaggacaac gtgtatacgt gacagaagta
    27721 gtagctgaca acttccaatt gctggaaagt cgttctgcat ctgaaaatcg ccaacaaagc
    27781 ggcggattcc aaagttctgg tcaatcagct ggcggatttg gcggaaacaa taactctaat
    27841 caaacatctc aatcatccaa cggtatgcct gatttcgacc gtgatacttc tgacccattc
    27901 ggctcaagtt caacgatcga catttcagac gatgatttac cattctaaac gaatttgata
    27961 ggagggaaat agaatggcac aacaaagaag aggcggacgt aaacgtcgta aagtagacta
    28021 cattgctgct aaccatattg aatatatcga ttataaagat atcgaattac taaaaagatt
    28081 tatttcagaa cgcggtaaaa tcttgccacg tcgtgtaact ggtacaggcg ctaaaaacca
    28141 acgtaaaatt actgttgcaa tcaaacgcgc tcgtatcatg ggcttgctac ctttcgttag
    28201 cgaagactaa taaatcctag gaattgaatg actgatcctt ttgatcagct attcaattcc
    28261 tttttttctg taaaaataac ctctattcgt ttagtcgctc gaatgacgaa agttatggta
    28321 aaatcaaatt agtcatatat gggaggaaaa ttatggaaaa taaaaacaat catttatccc
    28381 cgaaacctct cttccttatc ctgtttatat taatcgaagt attggtagtc ttaattttac
    28441 catttcgttt tgttagcgct tcggtcattc tattgatgaa tttatggggt gttcgctatt
    28501 ggttgaaaat gaaacgttgg cttattttaa ataaacgtga aaaaatccag caggcttcga
    28561 ctgtagctga aaccaatcta gcttatgtct cagaagtcat gcctgtagga gtgattgctt
    28621 atcagccatc aagccaaaaa atcgaatggc tcaatccatt agcattgaaa atcaaagatc
    28681 aaagtggatt aacagaggaa gaattgctag atactttttt tactgcaaaa gaaaaaaaga
    28741 aaaaccaagt ctatctagca gataaaacat ttcagtttga tatggataca gtaaagggtg
    28801 ttgtttattt taatgatatt acccaaaacc agttgttaaa actccatcag acgaacagtc
    28861 agccggtgat tggtatttta tctattgata actatgcaga tgccattgat aaattggatg
    28921 acaaagagat ttcttatttg aactctttcg tcactacact agtttctgac tggatgaatg
    28981 aataccatgt ctttttcaaa agaatcaacg cagaacggtt tttcttcgta gcacagatga
    29041 tcgatctgaa aaagatgatg gataaaaaat ttgatttgct ggatcgcttt cgagcagaag
    29101 ctgaaaaaca gagctcgcct atcaccctta gtatggggat tgcttatggc tcaagaaccc
    29161 tcgatgaaat cggtggagaa gctcagaata atttagatgt tgctttagtc cgtggaggcg
    29221 accaagttgt cgtgaaagag gtaaaagaag gagcaaaacc tgtttattat ggggggaaat
    29281 ctgctaagaa tgtcaaacgc acgcgtgttc gttctcgagc gatgagtacc gctttgcgtc
    29341 ggatttttga tgaaacaggc gatgtgttta tcatggggca caagtttccg gatatggatg
    29401 ctttaggctc tgcttttggt gtcagttgtc tggcacgctt caaccagaaa aaagcttaca
    29461 tcgttatcaa cgagaacgag atcattccag atgtagaacg gtgtcttgaa gaaatccata
    29521 agcatcctga attagaaatg caactaatct ctccagaacg tgccatagag ctgaaaaaag
    29581 aagaggacct cctcgtgatg gtggattacc ataaaccttc tctatcgatc tctcagggcc
    29641 tatatgagca atttgataag attgtgatca ttgatcacca tcgtcgtggg gaagagtttc
    29701 caagtaaacc tctgctgact tatatcgaat cttcagcttc ttcagcttca gagctagttt
    29761 ctgagctgat ccaataccaa agcagcaaaa caaatcgctt agatcgtttt gaggccacat
    29821 tattgcttgc agggatggtt gtagatacaa atagtttcaa tgtccgtaca actgcacgaa
    29881 cttttgacgt tgccagctat ttaaggtctt gtggagcaga cgcatcctta gtacaatatt
    29941 tattgagctc ggatttagcg acatacttgg agatcagcaa tttgattgct ggaagcgact
    30001 atgtgacttc tgatattgtt gtggcggcag ggacagacga aaaagagtat aatagtgtta
    30061 tagcagcaaa aacagcagat acattgcttt cgatgatcaa tatcaatgca gctttcgtca
    30121 ttacaaagcg gacagacggc ttgattggga tcagtgccag aagtaccggc acgatcaacg
    30181 tccaaatcat catggaatcc ttaggtggcg gaggacactt cacaaacgca gctactcaac
    30241 tggaaaatac gacagttgag gaaacaaaac agaagctatt tgctgcaatc aaagaaaata
    30301 tgaatcaaat atatgataag gagtaatcca aatgaaagta atttttttac aagatgtaaa
    30361 aggaaaaggt aaaaaagggg acatcaaaga agttccagca ggttatgcac aaaattatct
    30421 aatcaaaaat aacttggcaa aagaagcaac gaaaagcagt atcagtcagt tagcaggaca
    30481 aaagaaagca caagaaaaac acgaagctga aatcttggaa gaagctaaaa agttaaaaga
    30541 attcttggaa aaagaagata ctgtagtcga attgaaggcg aaagcagggg aagacagccg
    30601 tttgtttggt tcgatccctt caaaacaaat tgctgaaggg ttaaacaaac aatacaaaat
    30661 caaattagat aaacgaaaaa tcgaattaga aaatccgatc cgttcactag gctacacaaa
    30721 cgtacctgtt aagcttcatc atgaggtgac ggctacgatc aaagttcatg tcgtacaaga
    30781 ataacaaatc ttgatagcga tgttcagctg gtaagtataa ccagaaggaa aaaagacaaa
    30841 ccgaaattta tctgagaaaa cagctgcagc aatgaaagca aaagctgcaa atcgatttca
    30901 gattgatttc ggtttctttt ttgggaacag caaaatagca taaagaaaac gagtataata
    30961 aaagagaact atttttttat tacactttcg gtacgaatga tgacttttct ctcattttct
    31021 tgtaaaatga agcaattgaa gacaaggagc gatacgtatg aatgaagtgt ggcaggatcg
    31081 aatcccaccg caaaatattg aagctgaaca agcggtttta ggctctgttt ttcttgacgc
    31141 agaaacgatc attgatgcca tggagtacat agagccaaaa gacttttatc gtcgtggcca
    31201 tcaaattatt tttgagacaa tgatcgagtt aaatgatcgt aatgaagcga ttgacgtggt
    31261 tactgtcaaa gaccggctgg aacaagccaa tttgttagaa gatgccggtg gtttaagtta
    31321 tctctcagac ttggcattag cagttccgac agcagcaaat atcgtctact atgcgaaaat
    31381 cgttgaagaa aaatcattgc tgcgtacatt gatccagaca gcaacaggaa tcgttacgaa
    31441 aggattcgag caaggagaag aagttcaaac aattttagat gatgccgaac gcagtatctt
    31501 ggaggtttcg gaaaaaagaa atcgaagcgg ctttttatct attgctgaag tactgaactc
    31561 cacgattgaa aatatcgatc gactagctca aaacaatgaa gaaatcacag gtctaccaac
    31621 tggctatcaa ggtctggata aaatgacagc aggtttccag cccgaagaac taatcattct
    31681 tgctgcacgt ccagcggtag gtaaaacagc gtttgcattg aatattgctc aaaatgtagg
    31741 aacaaaaaca gatcgttctg ttgcgatatt tagtttggaa atgggggcag aatctcttgt
    31801 aaatcggatg ctttgtgcag aaggttcgat tgaggccagc catttacgta caggtcagct
    31861 ttcggaagaa gaatggtcga atctgatcgt tgcgatgggg agtctttctc gagcaaatat
    31921 ttttatcgat gatacaccag ggatcaaaat ctctgaaatc cgtgcgaaat gtcggaaact
    31981 agcgcaagaa aaaggcaatc taggcttgat attgatcgat tatttgcagt tgattgaagg
    32041 taacggtaaa gagaaccgtc aacaagaagt atcagatatc tctcgccaac tgaaaaaact
    32101 ggcgaaagag ctgaaagtac ctgtcattgc tctttcacag ttatctcgtg gagtagaaca
    32161 gcgacaagac aaacgaccag tgctaagtga tattcgtgaa tccggatcaa ttgaacaaga
    32221 tgcggacatc gtagccttct tgtatcgaga tgattattat gaaagagaag gcggagatga
    32281 cgatgatgga aacgagccaa aaaatgacaa cgtcatcgaa gtcatcatcg agaagaaccg
    32341 aagcggtgca cgaggaacag ttgaactact gtttatcaaa gaatacaata agttttcgtc
    32401 gctttcgcca agagaagaat tttaaagaag aggttgtgag ccttgagcaa tcccgagagc
    32461 tctcgtaaga agatgcaagg agtaaccgca ggaacgacta gagtacttaa tttaaacaga
    32521 tctccaaagg gattgtgaca aaagtcttgt cacagtccct ttttccgaat aaacggtgtt
    32581 caatcagctg acccttggta ttagctcagc aaacgtcaaa atatgaggaa ctattttgac
    32641 gtttgtttct ctaatactca ggtcaaaacg ctgatcttac gacctctttt ccttaaacgg
    32701 tgttctcctg ccaactcctc ggtcacaagt cacaatatca tcaaacatga gaagcagttt
    32761 tttgaaattg ctccttgtga ctcagagtta aacggcaggc tcacaacctc tttcttaaac
    32821 ggtgttcaaa agcttgcatc tgcggtaata cgcccaatca aacgaaaaat atgagaagct
    32881 atttttgttt ggctgttctt attacttgat gcaggacagc tttttcacaa cctctgattc
    32941 acggtgttcc aaaagtagct tcttcgaaaa ataagtcgaa atttcacaaa aatttgagaa
    33001 gcaattttcg tacattcctt cttatttctt gaagctgacc acttctgtta caacctcttt
    33061 tttaataacc attctaaaaa gataaagttc gttttttaag cgtttttata aaataaaaat
    33121 aaaaatcatt cgattttatt tgaaatatgt atctattatt gatacaatgg ttcaggatta
    33181 aataatatag aacgaggtgt tcacatgtca tctgtagtag tagtaggtac gcaatggggc
    33241 gatgaaggga aaggaaaaat cacagacttt ctcagtgaaa atgctgaagt gattgcacgg
    33301 taccaaggtg gcgacaatgc agggcacaca attaagttta acggtgtgac ttataaactg
    33361 catttgattc cttctgggat tttttataaa gacaagatca gtgtgatcgg aaacggcgtt
    33421 gtagtcaatc ctaaatcatt ggttaaagaa ttagcttatt tacatgaaaa aggtgtagaa
    33481 acaagtaatt tgcgtatttc tgaccgcgcg cacgtaatct tgccttatca tatcaaattg
    33541 gaccaattac aagaagatgc taagggcgaa aataagattg gtacaacgat taaaggaatc
    33601 ggacctgcct atatggataa agcagctcgt gtaggtatcc gtattgcaga cttattagat
    33661 aaagaaattt ttgaagaacg tcttcgtttg aatctagatg acaaaaaccg tcaatttgta
    33721 aaaatgtttg attcagaacc acttgatttt gacgatattt ttgaagaata ttatgaatac
    33781 ggacaacaaa tcaaacaata cgtcacagat acttccgtta tcttgaatga tgctttggat
    33841 gcaggcaaac gcgtgttgtt tgaaggcgca caaggtgtaa tgctggatat cgaccaggga
    33901 acttatcctt ttgttacttc ttctaaccca gtagccggtg gggtaacaat cggaagcggt
    33961 gtagggcctt caaaaatcaa taaagttgtc ggcgtctgca aagcctatac gtcacgtgtc
    34021 ggtgatggac catttccaac tgaattattt gatgaaacag gagaacaaat ccgcgaagta
    34081 ggacgagaat acggtacgac aactggtcgt ccgcgtcgtg taggctggtt tgattctgta
    34141 gttatgcgcc attctaaacg agtttcaggt attaccaacc tatctttaaa ctcgatcgat
    34201 gtattaagtg gattggaaac agtaaaaatt tgtacggctt atgaattaga tggcgaacta
    34261 atctaccact atccagcaag cttgaaagag ttgaaccgct gcaaaccaat ctatgaagaa
    34321 ttgccaggct ggtcagaaga cattacagga tgcaaaacac ttgcagaact gccagaaaac
    34381 gcacgtaact atgtacgtcg tatctcagag cttgttggtg tacgtatctc aacattttct
    34441 gtcggacctg atagaacaca aacaaacatc ttagaaagcg tctgggcgca aatctaagga
    34501 taaaaacgac gactgaatca ggacgttctt accagagcga gtcgaagtgt ttatctatac
    34561 gataataata acttgaagag gtagtgaaag agacgtttag ccttattgcc gataggctgt
    34621 ctcttgaaca ctgtttattc agaataaggg actgtgacaa aaaccgtgtc acagtccctt
    34681 tttccgaa
//
LOCUS       DAZKKZ010000029        34139 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.029, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000029 DAZKKZ010000000
VERSION     DAZKKZ010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 34139)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34139)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34139
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.029"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(99..1229)
                     /locus_tag="ACG8LA_001449"
     CDS             complement(99..1229)
                     /locus_tag="ACG8LA_001449"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003871 -
                     5-methyltetrahydropteroyltriglutamate-homocysteine
                     S-methyltransferase activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HFQ0203754.1"
                     /translation="MSKNRPFTVDHVGSFLRPQSIKEARKKVQEGLLSKEELRAIEDQ
                     EIKKLVEDQKAVGIKGITDGEFRRGFWHLDFLEELNGIEGYVPETGYNQTFHGKAAPA
                     YNIRVVDKLSFNPNHPFLKDFAFLKEVVETDDTFVAKATIPSPTMILRQEILSNDGSS
                     KIKEIYPDLSDFYEDLSSTYKAAIHAFYEKGCRYLQFDDTNWAFLADQTKREALLQKG
                     IDPKEMAHICTEIINNALEDKPEDLTITTHICRGNHASSWLFSGGYEPIAEELFSTNY
                     DGFFLEYDSDRAGDFTPLRHWSNKESKVVLGLVTSKFPDLEDTEKIKERIKEAQQFVP
                     LENLSISPQCGFASTEEGNHLTEEEQWKKIQLLQQVAKEVWL"
     misc_binding    complement(1289..1516)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(1878..3080)
                     /locus_tag="ACG8LA_001450"
     CDS             complement(1878..3080)
                     /locus_tag="ACG8LA_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFQ0203755.1"
                     /translation="MPKIKNIYQDKKTKKWFFRAYLGIDENGRKVQKTKRGYASQKDA
                     KIAYDKYMETHDFNKTIPNQLCSTNQMTFEEFYKDRFVKWYERQVKSQTYENAQFIFE
                     KRMQFFYHFRVRDITSHDIEDWLFELSQTESRNSRKKVNGETLSKSYINRIRGHLKIV
                     LDRAVKEGVIAKNPVEDVSSLPSENKKVEFWEHSEFQKVMNELKDDKIQTHHRKIVYE
                     MLFYTGIRIGELEALSWSNVDFEKNTITIEKTLIYNTKDDWYFSTPKTKCAYRTIGLG
                     KKLSLKLRQWYDLQKRIGNFEYVAQLDGTFTPPYSFANWLKEAAKKAGVKPIKLHALR
                     HSHVAFLIEQNIQPLSIQERLGHANIQITLGTYGHLYAKSDQQVVSAIDNVQEGAILS
                     KNDNLLPV"
     gene            complement(3140..3343)
                     /locus_tag="ACG8LA_001451"
     CDS             complement(3140..3343)
                     /locus_tag="ACG8LA_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HFQ0203756.1"
                     /translation="METKCDFMVNRAILIEMGFKPSQAARMIKESKAYLARIEGIDFY
                     NNRQVGVVPSRVIEHLFHIQVAE"
     gene            complement(3485..4552)
                     /locus_tag="ACG8LA_001452"
     CDS             complement(3485..4552)
                     /locus_tag="ACG8LA_001452"
                     /inference="COORDINATES: protein motif:HMM:NF014537.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HFQ0203757.1"
                     /translation="MLDSLQEEVVPVNRVLIDYLTIHFFSNQHLKLIEEIIEMPIERF
                     EELDYAPKGYIGQYVWNQVITIRYSIDDAVKGTVMEFSGQGCKHLARWLKTRKTNWQQ
                     FFRKVLDYQGNFTRIDFTLDDFVGSLSIPELKHKVILGHVWTTFQVSESHGGTDIINN
                     ESNGETLYLGSKKSQCRFCFYQKDHEQRKRRGIPLEEAKVKNRFELRYRKEKAQSLAK
                     IISKTHDLTKLFFELLNGAICFYDRDPNDLGAKVDAKWAAFISNYGAITISLDTIPQS
                     FEKTMSWLIHGVSPSLVFIAQVDQTFHSSLLPLIIEQGEMNPRQIKLLQNMKADPEYY
                     QEEVEYYERKLQSISNEKTSY"
     gene            complement(4610..4717)
                     /locus_tag="ACG8LA_001453"
     CDS             complement(4610..4717)
                     /locus_tag="ACG8LA_001453"
                     /inference="COORDINATES: protein motif:HMM:NF013540.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0203758.1"
                     /translation="MNQVNQHDLGEAIRVSREERGWTQRYLAEKVGISR"
     gene            4880..5692
                     /locus_tag="ACG8LA_001454"
     CDS             4880..5692
                     /locus_tag="ACG8LA_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0203759.1"
                     /translation="MEIDKQAVGNRIRQIRQELKLSMEKFGKLIGDLPRSTVNNWERG
                     INLPKTETLHQIAEIGHVTNEYLLYGDQENQYILEMLQKKAGKLDPKIEGLIVDEIKH
                     ADLVSEKEMDRMIEFFITNLIPPTEQDQFTFQCIDEKKQLYLGSTNFGKEAQLYLQHD
                     NQNHILHMMPFTFSNFSVDRILVYLANQKSYSYFGKHLPKELGEKAILLYSINQLTSD
                     VRIAPLVYSEETASYQYTEDNQYLLEQQYLYLPFVMEVEKERLLNAAYPSSK"
     gene            complement(6066..6257)
                     /locus_tag="ACG8LA_001455"
     CDS             complement(6066..6257)
                     /locus_tag="ACG8LA_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0203760.1"
                     /translation="MKQKFFIAIIATKKFHRGKRFGQKWKFPPKVTAPQLKSIKELEF
                     ENALVICMTCTDEVFRKHF"
     gene            complement(6502..6732)
                     /locus_tag="ACG8LA_001456"
     CDS             complement(6502..6732)
                     /locus_tag="ACG8LA_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0203761.1"
                     /translation="MNFFGDRFFQPYKINRNSIIESCDYKKIARKKKKVSIHFKYFIP
                     ISIAKKVEILYLPLTLASLANVVSILIDNKLR"
     gene            complement(6716..6913)
                     /locus_tag="ACG8LA_001457"
     CDS             complement(6716..6913)
                     /locus_tag="ACG8LA_001457"
                     /inference="COORDINATES: protein motif:HMM:NF016526.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0009372 - quorum sensing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HFQ0203762.1"
                     /translation="MLLRFLFSFCCALYTLRIFTGGVHLNSNILCYFMSVVIVIVAYQ
                     CMFIFRNVDFIILGLMFEFFW"
     gene            complement(7059..7937)
                     /locus_tag="ACG8LA_001458"
     CDS             complement(7059..7937)
                     /locus_tag="ACG8LA_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HFQ0203763.1"
                     /translation="MIYGAIEAGGTKFVCAVGTEELTILERVSFPTTTPVETMKQVID
                     FFKPFKEQLAGIGVGCFGPIDIQCKSTSFGHITSTPKLAWQNFNFVGTLKQYFNIPIE
                     WTTDVNAACYGEYVAGSGKGLAGVAYFTVGTGIGGGALFNGTFVEGFSHPEMGHMLIK
                     RHPKDNFSGNCPFHQDCLEGMAAGPAIEKRLGVKGQNLLADDSFWQIEAFYLAQCAYN
                     TTLMFSPDRIIFGGGVMKQEHMKKKVQDKFVELINGYVEIPPIDSYIITPELGDNAGI
                     IGGLALARKAVRNKQP"
     gene            complement(7976..9094)
                     /locus_tag="ACG8LA_001459"
     CDS             complement(7976..9094)
                     /locus_tag="ACG8LA_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 172 protein"
                     /protein_id="HFQ0203764.1"
                     /translation="MSILKNITQFKKIQSRAITPENPTGEKGKAAMLPSELGPSRKGR
                     GAIPLTSGEETVIADITGTGIIRHMWMTIRDRTEFGSFVLRDLILRIYWDGSDSPAVE
                     SPLGDFFCNGFGERCEVNSLPIVVNPTGGFNSYFEMPFQTSAKITIENLHPKDMSSFF
                     YTINYALVDELEENSLYFHANWHRERITKLQEDYKLIDRLKGQGYYVGTYLALTCLER
                     YWWGEGEFKFYIDGDSEYPTVTSTGSEDYFGGAWAFHEYDEFGRPHAKNYSTAFLGYP
                     YQSNRDATRDRFETGKLNAVHAFGDDAMPRHGLYRWHLQDPICFTEDLSVTLQQIGND
                     DVRLFERQDDVASVAYWYSTEASGNTKRHFTDRERLPR"
     gene            complement(9091..11190)
                     /locus_tag="ACG8LA_001460"
     CDS             complement(9091..11190)
                     /locus_tag="ACG8LA_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase"
                     /protein_id="HFQ0203765.1"
                     /translation="MTINEVIYSPKHPFFNAELNDGNVTTSNEYSYYRNIPDVKGLTF
                     DVSNQKTLANLDVCGTIQTLTFYRENLLTEEKPGVWVNKQLSQTNSLSLKVEVNGIVY
                     HLSESDHRIEVDVIQDCLPRYIHHYSTFKVIVVSFAPILANKRLSMLVQQVYIVNETH
                     ESLQVSVKDVPSYQEKYSDQQNVLISQKGNKDTIAQQEVASFAIAFVDPNAFEEVMTF
                     QESDIEKWLKETLNYFAQLFGQLSMPNDRVVHLYRRALYQSFSSFGMNRQGQVVGSNW
                     GSYPATNRIWNKDMYYASLPFTMFEPELCQKTVLWFDQYGVKFPGSKFTGGINHSLSN
                     SLSSALLASLYFEHTGDTKFFERCPQVLLNASRIIEDILAQRRSGEPMLFPSVWLSDA
                     FALGKYHTGSNLCLWKACIGLAEIFEALEQLSLSKRYKNIACKLKESICKQMTIDGPF
                     GEQFLEGIGDEEKTTYSVKHYQKPILEQGLIFLSDVIVDGKINLLMHDGEESDTTLMP
                     FYQFLDNKDHLYQNTMAFSASSFNPTYSEEIKGITWGLESGATFPGFITVLMSELHNP
                     QAFVTRLEELICLADLDGSWWWWPYRLEAQQGEVVRDFGCGKCGWASGLFVSLMISQY
                     FGLKFKKGVLQIDPVDNLTFSWKNLKFGQAFISIECTQSELSISNLSEKPLKISDTKK
                     ILHVEKGKTIHIQRRKR"
     gene            complement(11241..12062)
                     /locus_tag="ACG8LA_001461"
     CDS             complement(11241..12062)
                     /locus_tag="ACG8LA_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HFQ0203766.1"
                     /translation="MKLADGISKDEKKLVRKMFWRSMTMYASVNPVTMGGGGFAYSMM
                     PFINHFYKSEEDRAAALERHTQYFSTTIPCASFVMGIAASMEKENSEKAGFDVESINA
                     IKTSLMGPLAGIGDSLFWGVWRVVTAGLAINLANAGNILAPIIFLVMFNIPNYLMRYY
                     GGVLGYSLGSKYIEKLYANGLIEILTKAASILGLIMVGAMTISMVKFNTVLSFSMKGE
                     ELMNVQEILDSIFKGIVPLLVTLSCFKLLDKKVGVIKIIFGMVVLGILLSLLGIA"
     gene            complement(12059..12868)
                     /locus_tag="ACG8LA_001462"
     CDS             complement(12059..12868)
                     /locus_tag="ACG8LA_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0034219 - carbohydrate transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HFQ0203767.1"
                     /translation="MYDAFVVALAVFIGVAGHEMFGMSMLSRPIVVAPLAGALMGDLQ
                     TGLIVGASLEAIFMGVVNIGISSTAEPSLAAGLATAFAIKMGGNVDAIIPIVFPLAVL
                     GLQLMNMIFSFVCGPMAAKFFKFAKSGDQKGIINLHFFMWFVHYALYALIPFFAVLFG
                     ADVVKSVLDNIPEVIMNGLTVAGNLLPAVGMAMLLRMLWSKNIAVWFFFGAVVMAYLE
                     LPLIAIAAVGTIIAIVIAQRDLQLKNISVHAVQSDAAVNATLDQEEEDFFQ"
     gene            complement(12889..13383)
                     /locus_tag="ACG8LA_001463"
     CDS             complement(12889..13383)
                     /locus_tag="ACG8LA_001463"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFQ0203768.1"
                     /translation="MIKAVRIDERLIHGQVAMTWTKSLNLTGLVVASDEAATNDIQKM
                     TLKMAAPSNVKVIIKTVDDAIHLLKDPRAKDMRLMVLVPNVKDAVKVAKAFPTEIELM
                     NVGNAGKMTPPSEDKKTLSKEVMLTTSEIQDLKELVELYPDTVFQPTPAMEKRSAISI
                     LSDF"
     gene            complement(13395..13895)
                     /locus_tag="ACG8LA_001464"
     CDS             complement(13395..13895)
                     /locus_tag="ACG8LA_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFQ0203769.1"
                     /translation="MIKPMFLKVGTGIAYIKVNRKKGINHMKKILIATHGHLASGFLS
                     SIQLLTGKVQEITVINAYVDECDFEQELNVFVNQVNEQDQIFVFTDLFGGSVNQKITK
                     TFLEKEIAVTILSGFNLPILLEIVLATKELTKEDIQELVNKCQQELKMTILDEVHVVN
                     EEEDFF"
     gene            complement(13960..16656)
                     /locus_tag="ACG8LA_001465"
     CDS             complement(13960..16656)
                     /locus_tag="ACG8LA_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFQ0203770.1"
                     /translation="MEYKYRIDILQPIVYYAFRHIKLEEKMKKSAKDRVFDELIRLTG
                     NMSSVTAEKISKNLGISRQNASHYLTRLVEDKKVEKLPGKPVLWKPLDEYAVVDNTEQ
                     INEAFHSVVGHDGSLREVIQKCIAAVKYPPNGLSVLINGATGVGKSFLATKIFEYAIH
                     EQIIEKDAPFAILNCADYADNPELLSATLFGYKKGAFTGAEKDTDGLLATANNGYLFL
                     DEVHRLSKENQEKLFLFIDTGNYRPVGENVNWHSAKVRFIFATTEKGENYLLDTFDRR
                     IQISVMLPTFEDRPIRERLELIQLFFQNEADVLQKDIIVSREALSLMLSHPFSGNIGK
                     LKNIIKISCADVYSRTQEEPLTIGKNEILIQLNMLESEVESLPIASLLIKKNQKIKTD
                     RIKPFDYDSILEKITQLINEGNFNENFSSIKNEVQHLVHHIDKDSFLSMSRKLMIQMF
                     RKVWVSVLGKTYGLTTSGPVAEIISRSYVISPSYKTDLTGINRTLAANLPRTTYLCNQ
                     FLEHLPPLSEKDENFLRLLIVVTLSDYVDESIELKGLLLAHGDSTASSIQAVVNQLCG
                     NYVFEALDMPVESNVSEIVESTRNFVKRQVNTDSLVLIVDMGSLNQIYTQIKNDLKGE
                     LLLLNNLTTSIALDIGLKMTMNAPFKQIAEDAADKYSINVQYFEGFSQSSNIIISCMS
                     GLGISDKLKDVFRHHLSDESIEVFTKDYRELRELIDQNDETYFDKTKLVITTSDLPRS
                     FSIPNINVYDILDGDGAANLEHILSPEMKPAEFNRLIQELVKFFSLEGIADRLNFLNP
                     TIVMSEVETVISKYENYYHFTLNGRVKLNLYMHTALMMERLFLARTEKSEEPNYDLKP
                     DEDEFYYVSRSIFQSMEMKYNFKVNAYELSLLYELLGPYIQK"
     gene            complement(17084..18178)
                     /locus_tag="ACG8LA_001466"
     CDS             complement(17084..18178)
                     /locus_tag="ACG8LA_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFQ0203771.1"
                     /translation="MKKLQSLFLGILIIIAVLLLGVRQLEKTSGMSGAKVLTIYNWGD
                     YIDPSLITKFEKEYGYKVNYETFDSNEAMFTKIQQGGTNYDIAIPSEYMIQKMIKEKL
                     VLPLDHSKIKGLNNIDPRFLDLDFDPDNQYSIPYFWGTLGIVYNDKFFDANQIKHWDD
                     LWKPELKDSLMLIDGAREVMGLSLNSLGYSLNSLGYSLNSKNMAQLTEAANKLNHLTP
                     NVKAIVADEIKMYMINEEASVAVTFSGEAADMMWENEHLHYVIPPEGSNLWFDNIVMP
                     KTVKNKEGAYDFINFMLEPENAAQNAEYIGYSTPNEEAKALLPKDISSDEQFYPSDDT
                     ISHLEVYKDLGSKYLGIYNDLFLEFKMYRR"
     gene            complement(18175..19002)
                     /locus_tag="ACG8LA_001467"
     CDS             complement(18175..19002)
                     /locus_tag="ACG8LA_001467"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFQ0203772.1"
                     /translation="MKKFKWSYLYLGIVFLFLYAPIFYLIFYSFNEGGTMNSFTGFTW
                     ENYEAVFEDTRLIIIVLNTFMLAFLSALIATIIGTFGAMGIYYTKKRRARTALLSMNN
                     ILLVSPDVIIGASFLIFFTLLGFGLGFQSVLLSHIAFSIPIVVLMVLPKLQEMNDSMV
                     DAARDLGANNFQVVKNIILPYLSPGIIAGYFMAFTYSLDDFAVTFFVTGNGFTTLSVE
                     IYSRARQGISLEINALSALVFLFSMILVIGYYFISKENRPKRLKKNRRVREGVARLR"
     gene            complement(19003..19809)
                     /locus_tag="ACG8LA_001468"
     CDS             complement(19003..19809)
                     /locus_tag="ACG8LA_001468"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFQ0203773.1"
                     /translation="MKTMRRIYSVPYILWLGLFVIAPVLMIIYQSFFDMNGQFTLNNY
                     LSYFTSGTSLSMTINSVWYAFLITFFTLIISYPTAYFLTKLKHKQLWLMLIILPTWVN
                     LLLKAYAFIGIFSVHGSVNHFFDFIGIGPKQILFTDFSFLFVATYIEIPFMIMPIFNA
                     LEEMNPSLISASRDLGANSFETFRRVIFPLSLNGVKSGVQAVFIPSLSLFMLTRLIGG
                     NRVITLGTAIEQHFLVTQNWGMGSTIGVILIIAMFIVMLLTGEKKKGGRS"
     gene            complement(19821..20906)
                     /locus_tag="ACG8LA_001469"
     CDS             complement(19821..20906)
                     /locus_tag="ACG8LA_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016185868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0203774.1"
                     /translation="MGKPIISFDQVVKRYDDETVLKKVSFEIEQGKFYTLLGPSGCGK
                     TTILRIIAGFTEATEGDIYFEGKRLNDLPANKRQVNTVFQDYALFPHMNVFDNVAFGL
                     KIKKMSKSDIEKKVKDALRMVQLPGYEKREISEMSGGQRQRVAIARAIVNEPKVLLLD
                     EPLSALDLKLRTDMQYELRDLQQRLGITFIFVTHDQEEALAMSDEIFVMNKGKIVQSG
                     TPVDIYDEPINHFVADFVGESNIVDGVMIEDNLVEFVGKQFECVDGGMRLNEPVEVVL
                     RPEDLTITTPDKGKLVVTVDTQLFRGVHYEIICYDEQQNEWMVHSTKKAKEGSKVGLA
                     FEPEDIHVMRFNESEEEFDARLDSYEE"
     gene            complement(20923..21465)
                     /locus_tag="ACG8LA_001470"
     CDS             complement(20923..21465)
                     /locus_tag="ACG8LA_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HFQ0203775.1"
                     /translation="MEIGEKLRNLRIQKNLTQEELGERTDLSKGYISQLERDLSSPSM
                     ETFFSILEVLGVTPEEFFHQEAANLQVVYSKEDHTVYFDEENGYELEWLVADSNEKEM
                     EPVLLTFEGAGEYKTFEPSLSETFIFVLEGELELSLGETVYVAKAGQSIYYQATKQHQ
                     LRNHLKKRTKVLIVATQSYL"
     gene            21723..22712
                     /locus_tag="ACG8LA_001471"
     CDS             21723..22712
                     /locus_tag="ACG8LA_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HFQ0203776.1"
                     /translation="MNAFRSFQVIKEPVFHTAISDLPFTELAENEVLVKIAYSDVNYK
                     DALAMSESGQVIRTYPMTPGIDLSGTVVQSNNPRFSKEDLVLATGFGLGVTHPGGYSQ
                     YQKVPGDWLVPLPKNMTLRQAMILGTAGFTAMLCVNALIRQGMTSDKKVVVTGASGGV
                     GSTAIALLHKLGFQSIITFSRKEESVTWLKSLGALQVVRPDEFLPETTKALGKQQIDY
                     VIDTVGGEQLSSLLPLISYNGAVALCGNAGGIKLNATVLPFILRNIQLIGIDSVNVPI
                     DQRLSLWQQMADLQIADELVVQEITLDQLPETASKLLAGTHQGRTLVNVGDHK"
     gene            22709..23446
                     /locus_tag="ACG8LA_001472"
     CDS             22709..23446
                     /locus_tag="ACG8LA_001472"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014386989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HFQ0203777.1"
                     /translation="MKILITAGGTTEKIDQVRAITNHSTGRLGQALADYLAANPDTTI
                     DYVTTKQALKPKRHSNITIYTIESALDLFLQLEELTKKEHYDAIIHSMAVSDFTPAFS
                     FSEEQLAKNLPTSSTQEELDNWFAENEQTDTTVSKISSNTEHLVLVLKKTPKIISYLR
                     EWQPKAKIIGFKLLVDVPKESLLAVAKNSLINNKTDFIFANDLTEIHGETHHGYLLSK
                     DGTVEEAQSKSEIAALITEKIRLEESK"
     gene            23443..23994
                     /gene="coaC"
                     /locus_tag="ACG8LA_001473"
     CDS             23443..23994
                     /gene="coaC"
                     /locus_tag="ACG8LA_001473"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004633 - phosphopantothenoylcysteine
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HFQ0203778.1"
                     /translation="MKKILLGVTGSISAYKSADLTSQFVKLGAQVDVIMSKSSTHFIT
                     PLTLQSLSKRAVHTDVMQESNPQVINHIELAKQADLFLIAPATANIIGKLANGIADDL
                     LSTVAMALPVGTPKLIAPAMNTNMYQNPITQRNLETLRSVGYQEIEPRESLLACGDFG
                     KGALADIQTIIEQVMLTLNERNA"
     gene            24010..24642
                     /locus_tag="ACG8LA_001474"
     CDS             24010..24642
                     /locus_tag="ACG8LA_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HFQ0203779.1"
                     /translation="MKNTKNFTLTAMFLAILILLAVTPLGFIPIGPINATTMHIPVII
                     ASIVLGPRLGAFLGGTFGLISMIRSTVIQTPLSFVFSPFIPVIGTEHGSWKALLIAFI
                     PRILIGVVPYFVYKGLRKLMKQKADSVSLFLAGLSGSLTNTILVMNMIYFLFQQDYAK
                     VIGTNLNAVYSAILAVIFTSGIPEGIVAGLATAAVCNVLLRYFKHPSLTN"
     gene            24727..25374
                     /locus_tag="ACG8LA_001475"
     CDS             24727..25374
                     /locus_tag="ACG8LA_001475"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-binding oxidoreductase"
                     /protein_id="HFQ0203780.1"
                     /translation="MKIFVVGANGQIGRHLIKDLAPSSHEIFAGVRDVASQTLVKKEN
                     VSYVSFDLTWSVEKMTEAFKGIDVLIFAAGSQGKNLLQVDLDGAIKTVIAAENAHVSR
                     YLMVSAVYADEPAKWPESMTDYYITKHYADEWLKRTNLDFVILQPVTLTNDEEVTSIQ
                     LTKPNEKASKTITRSTVAAVLAALVEETDISRTTLVLSEGSKELNTAFQEWAKEE"
     gene            25379..26362
                     /locus_tag="ACG8LA_001476"
     CDS             25379..26362
                     /locus_tag="ACG8LA_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-quinone oxidoreductase"
                     /protein_id="HFQ0203781.1"
                     /translation="MRAISIKHPGSVDVLEQIEVPVPKPKQGELLIKVHTAAVNRTDI
                     MKRESVSLKPPYPILGVEVAGEVVENKSDISTFTPGTKVYGLVNLGGYAEYAVMPADR
                     AILLPDTLDYVSAAGISEVFLTAYQTLYWLGKLQEGETVLIHAGASGVGTAAIQLARQ
                     LSHAKIIVTAGSEEKLAFCKELGADELINYKKQDFQEEVRKITEGRGVDVILDFIGAS
                     YWEKNLASIAVDGRWVLIGMLGGTIVPEIDLGVLIGKRVQLLGTLLTPRSDQYKAELA
                     QTFMQKAGPFLENGKIRPIIDRTFQFSAVKQAHEYMEANKNIGKIILKITE"
     gene            complement(26765..28279)
                     /locus_tag="ACG8LA_001477"
     CDS             complement(26765..28279)
                     /locus_tag="ACG8LA_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavocytochrome c"
                     /protein_id="HFQ0203782.1"
                     /translation="MKKLVAGLLTAVALLAMSACGADQKNTAQTSSSTKESAEVSSGA
                     SEQVYTDPKEMKESYDVVIIGAGGAGMAAAIEAKDAGLNPVILEKMPVAGGNTSKSSS
                     GMNASETKFQKEEGIKDSNDAFYEETLKGGGGTNDKEMLRYFVDHSADAVDWLDQNGI
                     KLDNLTITGGMSEKRTHRPSDGSAIGGYLVEGLLNNVHEREIPIFVNADVTDIKKNGE
                     TVNEVTVHVQGEEPKEVTGKAIVVTTGGFGASKEFIEKYRPDLADYITTNQEGSTGDG
                     ITMIEKLGGQTVDMDKIQIHPTVQQDEGVLIGEVVRGEGAILVDQEGKRFVNEMDTRD
                     KVSAAITALPEKSAYLIFDQGVRDRATAIEFYDQKGYVTTGKTMEELAEKIDLPKETL
                     AKTVDGWNTDVAEKKDAQFNRATAMEHDLSSPNYYAIKIAPGIHYTMGGVKINTNTEV
                     LDKENQPIRGLYAAGEVTGGLHGNNRIGGNSVAEIIIFGRQAGIQAARFASENE"
     gene            28417..29223
                     /locus_tag="ACG8LA_001478"
     CDS             28417..29223
                     /locus_tag="ACG8LA_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0203783.1"
                     /translation="MNHLKTFFTNSTKTAGRITNGIYILLRIIVVIMLVDQVWNQHWG
                     NTMLLLLTLILFEIPYFLEKILKIQIPNMLEIILLSFIFSSTVLGELSDFYGYFSMWD
                     TFLHAFSGFLAGGVGFSLVYLLNKNTKTMNLTPLLLAVVSFCFSMTVGVMWEFVEFSA
                     DKLLQFDMQKDTIIQQINSVELSKDGNTVYHVPDITRTIIESQNADGKTDKTIIQNGY
                     LDVGIMDTMKDLFVNFIGAVVFSVFGYLYSRNDYQKFTFIKNFIPKKIKR"
     gene            complement(29398..29967)
                     /locus_tag="ACG8LA_001479"
     CDS             complement(29398..29967)
                     /locus_tag="ACG8LA_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFQ0203784.1"
                     /translation="MLDKTLPYAEIWMTRPLQQNVPITPLAEGFEFRFYQKEDESAWA
                     EIETSVGEFQTTDEALEYFQQNFAPYPEELERRMFFVETKKGEKVATCTAWRKKSREQ
                     VYPVFHWLAVKPDYQGKGLAKALTARVLQEFPTLHTDGPIYLHTQTWSHQAIALYKKM
                     GFTFIAENLDGTPNPDYEKVMQVLSKLDK"
     gene            complement(30050..32110)
                     /locus_tag="ACG8LA_001480"
     CDS             complement(30050..32110)
                     /locus_tag="ACG8LA_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HFQ0203785.1"
                     /translation="MCSKRRSKQLNKHACRLDKERSCSEKHYVKFMMRTMLISLSVGV
                     YMHVPVQATTQTIKVVRTSVSETTDSPITITHTFTDANGKQLLPALTSYNKVSYPPTI
                     NHYWLIPNKTLWTSETGSSVPLSIFSDMTDPTKGDQLKQITDILNHALTDIKDGGSAQ
                     VSYVYEKDYSQFERKKIDVLAGTKVSISDLVERLKNADGTQGDMSKVISNNGNIVDTT
                     NTGTSTISLSYFDPIALKTMTASAVIHVRADQTAIKGKDLHLRTGESYAPKDLVEYVT
                     KSDGTSGNKEEIKMNGTVDTTTPGEYPVVLTYIDSKTSNVAETTAVVYVEASAASSTV
                     ITHFIDSQTNKELQAETHMSSVNRIPDLRLPAEFSDRVPNIDLSTYEQNGKVTSISDW
                     MQANGLDRKSHWSEILEVLHSELMNNRKQSGGEITFTYVYIPDNRSLEGHDLIVHPNE
                     KINKEELIQSATNSLGKPVPLKDVSVTINEVPLEDGYLTKQTGDFTIMYSYHDPYSLQ
                     ELHAQSLLHVLPLNKQIDQKEQKRQEESLSEKKQQMAHAVSPTGKVKQTRSLELARIS
                     RKISESNKTIRQEAHLAPQVSGLENEILEPKIKQQSEKEFVAKQSEDQKESDDQKETK
                     KKRLSTIDSTDEHLQPQVPLPSPGTPAPGGGIPSSALGDFMRGMAGTWVYANRNEFDA
                     DDWF"
     gene            complement(32387..33865)
                     /locus_tag="ACG8LA_001481"
     CDS             complement(32387..33865)
                     /locus_tag="ACG8LA_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0203786.1"
                     /translation="MKLDYLIEEEDREKLLLARYLEFEKKNYVVLPKLYETLGLSKFK
                     TRNYIIELNKEFTEFKTKPEIQISEEAEIHVERLNLTDIKNLRRIYFQRSKIARLLTE
                     IVDSKVTIEKFAENHFLSISRAYVKRRELVSFLEQHQIKLKKNILVGEEINIRNVLFG
                     VYFGVFNGFSMPFRESVMNEAKSIVQYFEYLFNLKLSATKRIKFNLLTTISLLRAYGN
                     QPIGKRFFSDEYFKSSEGMKIIKDLSHISFLHIPKEQIIDEISYIMLFLITEEEFELD
                     GAFGLAEAHFHDIHMISQKMSVELIDQLPFSIEISEEERLYIRKELRMGMMHVNRKNW
                     IFDFEMTSFTSKKQLQFFFETYPIFSTAIQKVIQENKRYFLGKDERFMIRLFYDYLFL
                     LVGICPVSYFEAPIHVCIDFSQGSAYTDYIISQVKGFKNYNIVIESRITSRTNIYLSD
                     CLLEKFNKEQIIWKNPPTPDDWEYFGNTIIREKNRHLTEKIS"
BASE COUNT        10265 a         7086 c         5749 g        11039 t
ORIGIN      
        1 aaataaataa tataaaaggt aaataaaaaa gagtggattt ctccactcca tgaaaagccg
       61 actttttggg acgctttttt ttgccaagcc tcacattttt atagccaaac ttcttttgcg
      121 acttgctgca ataattggat tttcttccat tgttcttctt ctgttaaatg gtttccttct
      181 tctgttgaag caaacccaca ttgaggactg atacttagat tttccaatgg tacaaattgt
      241 tgtgcttctt ttattcgttc ttttattttc tccgtatctt ccaaatctgg aaacttagaa
      301 gtaactaatc ctaaaacaac tttactttct ttgttactcc aatgtcttaa aggagtaaaa
      361 tctcctgctc ggtcagaatc gtattccaaa aagaaaccat cataatttgt tgaaaacaac
      421 tcttctgcaa tgggttcata tccaccggaa aacagccaag aagaagcgtg attcccgcgg
      481 cagatatgtg ttgtgatcgt caaatcttct ggtttgtctt ccagtgcgtt attgataatc
      541 tctgtacaaa tatgggccat ttctttcgga tcaattcctt tttgaagaag tgcttctctt
      601 ttagtttgat cagctagaaa cgcccaattt gtatcatcga attgcaggta acggcaacct
      661 ttttcataaa aagcatgaat cgctgctttg taagtagagg acaagtcctc ataaaaatca
      721 gatagatcag gataaatctc cttgattttt gaagaaccat cattagatag gatctcttgt
      781 cgtaaaatca tcgtgggact agggatcgtt gcttttgcaa caaaagtatc atctgtttcc
      841 actacttctt tcagaaaagc aaaatctttt aaaaatgggt gatttggatt gaaagataat
      901 ttatctacta cccgaatatt ataagctggt gctgcttttc cgtggaatgt ttgattatat
      961 ccagtttctg gaacatagcc ttcgatacca tttagttctt ctaaaaaatc aagatgccaa
     1021 aatccacgcc gaaattcacc atctgtaatt cctttgatgc cgactgcttt ttggtcttcc
     1081 actaattttt ttatttcctg gtcttcgatt gcacgaagtt cttcttttga aagtaagcct
     1141 tcttgaactt tttttcttgc ttctttgatc gattgcgggc gtaagaaact tccgacatga
     1201 tctactgtaa atggtctatt tttgctcatt tcactcactc ttttctttgt tttttgtaaa
     1261 aaaaaatcct tttactagca aatactagta aaaggacgat tatactcgtg gtaccacctt
     1321 ttttcagaaa aaacattctt tctctcagcc tgacaataaa atcagtggtc ttggtaacga
     1381 aagactgttc gtttttgcct acctttcgac aaaaaatcct ctaaggccat tttcgacagt
     1441 caacttctag ctttttacac caaccaaagc ctctcttgaa ccattttctg tctactttcc
     1501 ttctcatcgg atactattag aataaaatta gaatagcatg tttgaaagaa aagtcaatag
     1561 ggaataagaa caaacaaaaa ctaatttgtt attcttagta atttgtttgt ggaatacaat
     1621 aaagcttttc taatatgata attgttcagt cgtcctttca tcttagatca cttccttaaa
     1681 atgatcatac ccgtttcaac cacataaaaa aggacttaat tttgaaaaat ttcccatcaa
     1741 aactaagtcc tttttattat agttatgcaa atttgcttat tttctcgcta tttccgatac
     1801 atcttgaaca ggagcaattc gactgaaaac actggtgcaa aagcatttat ttgtcttatg
     1861 gtagaaccgt ggaaaactca gactggtaat aaattgtcat tttttgaaag aatagcgccc
     1921 tcttgaacat tatcaatcgc acttaccact tgttgatctg actttgcata taagtgaccg
     1981 taagttccta aagtgatttg aatattcgca tggcccaatc gttcttgaat agatagcggt
     2041 tgaatattct gctcaattag aaatgcaaca tgagaatgtc gtagcgcgtg aagcttaatc
     2101 ggtttgacac ccgctttttt agcagcttct tttaaccagt tcgcaaaaga ataaggtggc
     2161 gtaaatgttc cgtccaactg agcaacatat tcaaaatttc caatacgttt ttgcaagtca
     2221 taccactgtc tgagttttaa ggaaagcttc ttccccaacc caatcgttcg ataagcacat
     2281 ttagttttgg gagtcgaaaa gtaccaatca tcttttgtat tataaatcaa tgtcttctca
     2341 atcgttatcg tgtttttctc aaaatctaca ttcgaccaag acaaagcttc aagttctcca
     2401 atccgaatgc cagtataaaa gagcatttca tacacaatct tccgatggtg ggtttgaatc
     2461 ttatcatcct tcaattcatt catcactttt tgaaactcac tgtgttccca aaactcaact
     2521 ttcttattct cagaaggaag cgaagaaaca tcttcaacgg gatttttagc aatcaccccc
     2581 tctttaacag cccgatccaa tacaattttt aggtgccctc gaatccgatt gatataagat
     2641 tttgataacg tttcgccatt aacttttttc cgtgaattac gtgactctgt ctggcttagt
     2701 tcaaataacc aatcctcaat atcgtgactt gtaatatctc gaacacgaaa atgatagaaa
     2761 aactgcatac gcttttcgaa aatgaattgc gcattctcat atgtttgact tttgacctgt
     2821 ctctcgtacc attttacaaa cctatccttg taaaactctt cgaaagtcat ttgattggta
     2881 gaacacagtt gattaggaat tgtcttgtta aaatcatgtg tttccatgta cttgtcataa
     2941 gcaattttgg catctttttg tgaagcataa cctcgtttag tcttctgaac ctttcttcca
     3001 ttttcatcta tacctagata cgctcggaag aaccattttt ttgtcttttt atcttggtaa
     3061 atatttttaa tttttggcat cgttccattc ctccctgtac ttgagaaaag ctactttaat
     3121 agtaccgcgc ttgtactgtt tattccgcaa cttgaatgtg aaaaagatgt tcaattactc
     3181 gggatggcac cacaccaact tggcgattat tataaaaatc aataccttca atccttgcaa
     3241 gatatgcctt gctctcttta atcattcgtg cagcttgact aggtttaaag cccatctcta
     3301 tcaaaattgc acgatttacc atgaaatcac attttgtttc cattctctca cctcctgatt
     3361 ctttactcct tttaaaataa tcctctttat aatctattgt ttctcattcg atggttgtgt
     3421 tatactcgtc ttgtcgaggc ggagtacgtt gcacaacttg ttgtgtaagc agtactttgc
     3481 ttttttagta gcttgttttc tcatttgata tactttgtaa ttttcgttca taatactcaa
     3541 cctcctcctg ataatactcc gggtctgcct tcatattttg gagaagtttg atctgtcttg
     3601 gattcatttc tccttgttca ataatcaaag gcaacaagga agaatgaaac gtttgatcga
     3661 cctgtgcaat aaaaactaat gatggtgaaa caccatgaat taaccaactc atagttttct
     3721 caaaactttg aggaattgta tctaaagaaa tggtgattgc gccataattg ctaataaagg
     3781 ctgcccattt ggcatcaact tttgcaccta gatcatttgg atcacggtca taaaaacaaa
     3841 ttgctccatt aagtaactca aagaacagtt tggttaaatc atgggttttt gaaataatct
     3901 ttgccaagct ttgcgctttc tcttttcgat accgtagttc aaagcgattc tttacttttg
     3961 cctcttctaa aggaattcct cgtcgcttcc gttgttcatg gtccttctga taaaagcaaa
     4021 aacgacactg actcttcttt gagcctaaat acaaggtctc accatttgat tcattgttta
     4081 tgatatccgt accgccatga gattcactca cttgaaaagt ggtccacaca tggcctagta
     4141 ttaccttatg cttaagttct ggaatgctga gactccccac aaaatcatct aaagtaaaat
     4201 caatccgtgt aaagttcccc tgataatcta ataccttacg aaaaaactgt tgccaatttg
     4261 tttttcgtgt ttttagccat cttgctaagt gtttacagcc ttgacctgaa aactccatca
     4321 cagttccttt aaccgcatcg tcaatggaat accgaatcgt gattacttga ttccacacgt
     4381 attggccaat atagcccttt ggcgcataat ccagttcctc aaaacgttca atgggcattt
     4441 caataatctc ttcaattagc tttaaatgtt gattcgagaa aaagtgaatg gttagataat
     4501 caatcaaaac acggttaact ggaacgacct cttcttgcaa actatccaac acaagattca
     4561 atttttcttc acttaattgt ctcgttcctt tttctacttt cgataataac tatctcgaaa
     4621 tccccacttt ttctgctaaa tatcgttgtg tccaccccct ttcttctcga gaaactcgaa
     4681 tggcttcacc gagatcatgt tgattaactt ggttcatcga caaacctcct tctgctattt
     4741 acttgtcaaa gaacctattg aacttatttt aagtacattt ttattgtacg cctgtattta
     4801 ttttaagtca atatgttttg acttttttta agtacacacg tatactaaat ttaagaactt
     4861 atcctgagga ggagttttca tggagataga caagcaagca gtcggcaatc gaattcggca
     4921 gattcgccaa gaattaaagt tgagtatgga gaaatttggc aaactaattg gtgatttacc
     4981 gcgaagtaca gtcaataact gggaacgtgg gatcaacctt ccaaaaaccg aaacccttca
     5041 ccaaatcgca gagataggtc atgtcaccaa tgaatatctt ttgtatggtg atcaagagaa
     5101 tcaatacatt ttagaaatgc tccaaaaaaa ggcaggtaag cttgatccta agattgaagg
     5161 tctcatagta gacgaaatca aacacgctga ccttgttagt gaaaaagaaa tggatcgaat
     5221 gattgaattt tttattacaa atctcattcc accaactgaa caagaccagt ttactttcca
     5281 atgtatcgat gaaaaaaagc agctttatct tggttcaact aattttggta aggaagccca
     5341 gctctatttg caacatgata atcaaaatca tattctgcac atgatgccct ttaccttctc
     5401 caactttagt gtggatcgca tactcgtcta tttagcaaat caaaaatcct attcctattt
     5461 tgggaaacat ttacccaagg aactaggtga gaaagccatc cttctatact caattaatca
     5521 attgaccagc gatgtgcgaa ttgccccgtt ggtctattca gaagaaaccg cttcttatca
     5581 gtacacagag gacaatcaat atctactaga acagcaatat ctttatctac cattcgtgat
     5641 ggaagtcgag aaagaacgcc tgttaaatgc agcgtatcca tcatcaaaat gaggtgacaa
     5701 aattgataag cacgtgacaa agaaaatact gctaggacac tccccaatgg gtagttgtca
     5761 cagtttcctg ttctttgtta gccccctgtt agaaccgggg gctttattcc tgcagtccgg
     5821 ctacgccttc ctgcaataga caaaactcca gatcgggtaa ttcgcttgtg gcgaaacccg
     5881 acctggagtt tgtctctgta ttttgaaccc taaaaattaa tcaaacagac tgatattctc
     5941 ataatcagcg cgaaataagc cattaagtac agttttccta cctatttttg ataacccgct
     6001 ggttagttaa tattcctttt ccgagagaga taaatgattg gttaaatcta tatacatctc
     6061 aacctttaaa aatgttttcg aaatacttca tcagtacatg tcatacaaat taccagtgca
     6121 ttctcaaatt ctagttcttt aattgatttc agttgaggag cagttacttt tggcggaaat
     6181 ttccattttt gtccaaacct cttcccccga tgaaatttct ttgttgcaat tattgcaatg
     6241 aaaaattttt gtttcaaaaa tatacataat tacttcctcc aataaaaact atctacctct
     6301 caaattattt ttctctaata agaaaaacag aaaaggtaat aagatacaac agtgatgatt
     6361 cctaataaag aaaagactac aataatattt ttctaactta tcgccttcaa agaaatagtt
     6421 tcttattttt cactaaaata aaaaatttat tgcaaaaaaa atagaagtga caaaattatc
     6481 aatcatttca aggtaatata actacctgag tttattatcg attaaaatgc taactacatt
     6541 tgcaagagaa gcgagagtta aaggtaaata tagaatttct acttttttag caatagaaat
     6601 aggaataaaa tatttaaaat gtatagaaac tttctttttt tttcttgcta tctttttata
     6661 atcacaactc tctataatag aattacgatt tattttatac ggctgaaaaa atctatcacc
     6721 aaaaaaattc aaacattaag ccaaggatta tgaagtcaac atttcgaaaa atgaacatac
     6781 attggtaagc aactataact attaccacag acataaagta acacaatata ttactattta
     6841 agtgtacgcc accagtgaat atcctcaagg tatacagcgc acaacaaaaa gaaaaaagga
     6901 aacgcagaag catttccttt cagtgattta atgaaaacaa cacgatttga cttagagcct
     6961 ttttatttga attcattttc gctttatcca acttcatttg atcatttgat tactcggtta
     7021 aatacttttg acatgagtat caatgaaaca ttcattaatt atggttgctt atttcttacc
     7081 gcttttctgg ccaatgctaa tccgccgatt attccggcat tatcacctaa ttcgggcgta
     7141 ataatgtagc tatcaattgg tggtatttca acatatccat ttataagctc aacaaattta
     7201 tcctgaactt ttttcttcat gtgttcttgt ttcattacac caccgccaaa aataattcta
     7261 tctggcgaaa acatcagtgt tgtattgtat gcacattggg caaggtaaaa ggcttcaatc
     7321 tgccaaaacg aatcgtcagc caataaattc tggcctttta cacccaaccg tttttcaatc
     7381 gctggtcctg ctgccatccc ctctaaacaa tcttggtgga agggacagtt tcctgaaaaa
     7441 ttgtcctttg gatgtcgctt gatcaacata tgccccattt ccggatgact gaacccttcc
     7501 acgaaagtcc cattgaacaa ggcaccacct ccgatacctg ttcccacagt gaagtatgca
     7561 acacctgcta accctttgcc agaaccagca acatattcac catagcaagc cgcattgaca
     7621 tctgttgtcc attcaatcgg aatattgaaa tattgcttta gcgttcctac aaaattgaaa
     7681 ttttgccaag caagttttgg tgttgatgtg atatgaccga aactcgttga tttgcattga
     7741 atatcaattg gaccaaagca gccgaccccg atgcctgcca attgttcctt aaaaggttta
     7801 aaaaaatcaa tgacctgctt cattgtttca actggagttg ttgtgggaaa actgactctt
     7861 tccaaaatcg ttaattcctc agtaccgact gcacagacaa atttagtccc tccagcttca
     7921 attgccccat atatcatcat aggttcctcc cttcgaatat gtgaaaaaca cttcattaac
     7981 gcggcaagcg ttctcgatca gtgaaatgac gtttagtatt tcctgaagct tctgttgaat
     8041 accagtaagc gacactagca acatcgtctt gccgctcaaa taagcgaaca tcatcgttgc
     8101 cgatttgttg taaagtgacc gataaatctt cggtaaaaca gatggggtct tgaagatgcc
     8161 aacgataaag accatgtcgt ggcattgcgt cgtcaccaaa ggcatgaacg gcattcaatt
     8221 ttcccgtttc aaaacgatct cttgtggcat ctctatttga ttggtaagga taccctaaaa
     8281 aggctgttga atagtttttc gcatgtggac gtccgaactc atcgtactca tgaaaggccc
     8341 acgccccgcc aaaataatct tctgaacctg ttgaggttac ggtcggatac tcactatccc
     8401 catcaatgta gaatttaaac tcgccttcgc cccaccaata acgttctagg caggtaagcg
     8461 caaggtaagt acccacgtaa tagccttgac cctttaatcg atcaattaac ttataatcct
     8521 cctgtaattt ggtaatgcgt tcccgatgcc aatttgcgtg aaaatatagg ctattttctt
     8581 ccaattcgtc caccaaagcg taatttatcg tataaaaaaa tgaggacata tccttcggat
     8641 gtaaattctc gatcgtaatt ttagcggatg tttggaaagg catttcgaaa taggaattaa
     8701 agccccctgt aggattaacc actatcggca acgagttcac ctcgcaacgc tctccaaacc
     8761 cattacaaaa gaaatcccct aaaggacttt caacagcagg gctatccgac ccatcccaat
     8821 aaattcttaa gattaaatca cgtaaaacaa aactgccaaa ttctgttcga tcacgaatcg
     8881 tcatccacat atgacgaatt attcccgttc cagtaatatc cgcaatcaca gtttcttcac
     8941 cagaagtcag cggaattgcg ccacgacctt tgcggcttgg tcctagctcg cttggcaaca
     9001 tcgcagcttt acctttctcg cctgttggat tttcgggagt gattgctcga ctctggattt
     9061 ttttaaattg ggtaatattt tttagtatac tcatcttttt ctcctttgaa tgtgaatcgt
     9121 ttttcccttt tctacgtgaa gaattttttt cgtatcactt attttcaatg gcttttctga
     9181 caaatttgaa atactcaact cggattgcgt acattcaatc gaaatgaagg cttgaccgaa
     9241 cttcaaattc ttccaagaaa acgttaaatt atcaacagga tcaatttgca atactccttt
     9301 tttgaatttc aatccgaaat attgactgat cattaggctg acaaaaagac ccgatgccca
     9361 gccgcatttg ccgcagccaa agtctcgcac gacttctcct tgttgagcct ctaagcgata
     9421 cggccaccac caccacgaac cgtctaaatc tgccaaacaa attagttctt ctaatcgggt
     9481 tacgaaagct tgagggttgt gcagctcgct cattaaaaca gtgataaagc caggaaaagt
     9541 ggcgccggat tctaatcccc aagtgatgcc tttgatttcc tcgctatagg ttggattgaa
     9601 agaactagca gaaaaggcca tggtgttctg atataaatga tctttattat ctaaaaattg
     9661 ataaaaaggc atcaacgtag tgtctgattc ttctccatca tgcatcaata aattaatttt
     9721 tccatccaca atcacatcac ttaaaaagat taacccttgc tcaagaatcg gtttttgata
     9781 gtgcttcact gaataggttg ttttctcctc atcaccgatt ccctccaaaa attgctcacc
     9841 aaaaggacca tcgatagtca tttgtttaca aattgattcc tttagtttac aggcaatgtt
     9901 tttgtatcgc ttgctaagac tcagttgttc tagggcttca aaaatttctg caagtccaat
     9961 acaggccttc caaagacaaa gattgctgcc ggtatgatac tttccaagtg caaaggcgtc
    10021 tgataaccaa acagatggaa aaagcattgg ttcccctgac cgacgttgag ctaatatgtc
    10081 ctcaataatt cttgaagcat tcagtagaac ctgcggacac cgctcaaaga attttgtatc
    10141 cccagtatgt tcaaaataaa gactagccag taacgcactg gataacgaat tactcagaga
    10201 atgattgata cctcctgtaa attttgaacc aggaaactta acgccatatt gatcaaacca
    10261 tagaaccgtt ttttgacata actccggttc aaacatggtg aatggcaatg atgcgtaata
    10321 catatcctta ttccaaattc gattagtagc aggatagctg ccccaattgc tgccgacgac
    10381 ctgtccctgt cgattcatac cgaaactaga aaagctttga taaagtgcac gacgatagag
    10441 atggacaact ctatcgtttg gcattgacag ctgcccaaat agctgagcaa aatagttcaa
    10501 tgtttccttc agccattttt cgatatcaga ttcctgaaaa gtcattactt cttcaaaagc
    10561 atttgggtcc acaaaagcaa tggcgaagct tgccacttcc tgttgtgcga tcgtgtcctt
    10621 atttcctttt tgagaaatca acacattttg ctgatccgaa tacttctctt gatacgaagg
    10681 cacatctttc actgaaactt gaaggctttc gtgtgtttca ttcacaatgt aaacctgttg
    10741 aacaagcata cttaaacgct tattagccag tatgggagca aaggatacta caatgacctt
    10801 aaacgtcgaa taatgatgaa tatatctagg caaacagtct tgaatcacat cgacttcaat
    10861 acgatgatcc gattctgaca aatggtagac aatcccgttt acttcaacct ttaaggataa
    10921 cgaattggtt tgagagagct gtttattgac ccaaacacct ggtttttcct cagttagtaa
    10981 attttctcga taaaaggtca acgtttgaat cgtcccgcaa acatcaaggt ttgctaatgt
    11041 cttttgatta cttacatcga aggtcaatcc ctttacatca ggaatattcc gatagtagct
    11101 gtattcgttt gaagtagtca catttccgtc gtttaactca gcattaaaaa atgggtgttt
    11161 gggtgaataa attacttcat taatagtcat cttttccctc cttgctaaaa aaactgcagc
    11221 ctagtagctg cagcttccta ctatgcgatt ccaagtaatg acaataaaat tcccaagacg
    11281 accattccaa aaataatttt gatgacgccg acttttttat ctagtaattt gaaacagctc
    11341 aatgttacca ataacggtac aattccttta aaaatactat cgaggatttc ttggacattc
    11401 attagttctt cgcccttcat tgaaaagctc aaaacggtat tgaatttgac catactgatc
    11461 gtcattgcac ctaccatgat cagacccaag atactagcag cttttgtcag aatttcaatt
    11521 aacccgttcg catacagctt ttcaatatat ttagagccta atgaatagcc taaaacgccg
    11581 ccatagtatc gcatcaagta attaggtata ttgaacataa ctaaaaagat aattggtgcc
    11641 aaaatatttc cggcattggc taagttgatc gctagtcccg cggtaacgac acgccaaact
    11701 ccccagaaca atgaatcgcc aattccagcc aatggtccca tcaaactcgt tttgatcgcg
    11761 ttgatacttt ccacgtcaaa accagctttt tcagaatttt ccttctccat cgatgccgca
    11821 atccccatga caaaggacgc gcaaggaatg gtcgtcgaaa aatactgtgt atgacgttcc
    11881 agcgccgcag ctcgatcttc ttcacttttg tagaaatgat taatgaaggg catcatagaa
    11941 taggcgaaac caccgccgcc catcgtcacc ggattcaccg aagcatacat agtcatcgag
    12001 cgccaaaaca tcttccgaac caattttttc tcatctttag aaattccatc agctaatttc
    12061 attgaaagaa atcctcctct tcttggtcaa gcgttgcatt tacagcagca tcgctttgaa
    12121 ctgcatgaac agatatattt tttagttgta gatctctttg ggctataaca attgcaataa
    12181 tcgttccaac tgcggcaatt gcaatcaatg gtaactcgag atacgccata acaacggccc
    12241 caaagaaaaa ccacacagca atatttttac tccaaagcat ccgtaacagc atcgccatcc
    12301 caactgccgg cagcagattt ccagcgactg ttaatccgtt catgatgacc tctggaatat
    12361 tatccaagac gcttttgaca acatctgctc caaataaaac ggcaaagaat ggaataagag
    12421 cataaagcgc atagtggaca aaccacataa agaagtgcag attgatgatt cctttttgat
    12481 caccagattt tgcaaatttg aaaaatttag cagccatcgg tccacataca aaagaaaaaa
    12541 tcatattcat taactgtaat cctaatactg ctagtggaaa gacaatggga ataatcgcat
    12601 ccacgtttcc tcccattttg attgcgaacg ctgtagccag cccagcagcc aaagaaggct
    12661 ccgccgtact agagattccg atattgacga cacccataaa gatggcttct agtgacgccc
    12721 cgacaatcaa ccccgtctgc aaatccccca tcaacgctcc tgctaacgga gcaacaacaa
    12781 tcggacgact cagcatggac atcccgaaca tttcatgtcc agcaactcca ataaaaacgg
    12841 ccaaagcgac tacaaatgca tcatacataa tttttctcct tcctttttct aaaaatcact
    12901 caaaatagag atagctgaac gtttttccat cgccggtgta ggctgaaaaa cggtatctgg
    12961 ataaagttca actaattctt ttaagtcttg aatttctgac gtcgttaaca tcacttcctt
    13021 tgataaggtt ttcttatctt ccgatggcgg tgtcattttc ccagcattcc ccacgttcat
    13081 taattcgatt tccgttggga aagctttcgc aacttttacc gcatctttga cattagggac
    13141 taaaaccatc aagcgcatgt ccttcgcccg cggatctttt aacaaatgaa tcgcgtcatc
    13201 aactgtttta ataatgactt tgacattcga tggtgcagcc atcttcaatg tcatcttttg
    13261 aatatcgttg gtagccgcct catcgcttgc tactactaac ccggttaaat ttagactctt
    13321 tgtccaagtc atcgctactt gtccatgaat taatcgttca tcaattcgca ctgctttaat
    13381 catttttctt cctcctaaaa aaaatcttcc tcttcattta ctacatgtac ctcatcaaga
    13441 atggtcatct ttaattcctg ttggcattta tttaccagtt cctgaatatc ctcctttgtt
    13501 aattccttgg ttgccaatac tatttcgagc agaattggca gattaaagcc agacaaaata
    13561 gttacagcaa tctctttctc caaaaaggtt ttggtaatct tctgattgac acttccgcca
    13621 aataaatcgg taaaaacaaa aatctgatcc tgctcgttca cctggtttac aaatacattc
    13681 aactcctgtt caaaatcaca ctcatccaca taagcattaa tcaccgtaat ctcttgaacc
    13741 ttccccgtca gtaattgaat actgctaaga aagcctgaag ctaagtgacc gtgagtcgct
    13801 attagaattt tcttcatatg gttaattcct ttctttctgt tcacttttat ataagcaatt
    13861 cctgtgccaa cttttaaaaa cattggttta atcacgttaa ttcacattaa aaaaagtgtc
    13921 taacctaaaa aaaacagatt agacactttt ttagacactt tatttttgaa tatacggtcc
    13981 taataattca tagagcagcg aaagctcata agcattgact ttaaaattat atttcatctc
    14041 cattgattga aaaatacttc tagaaacata ataaaattca tcttcatctg gtttcaaatc
    14101 ataattcggt tcttcagatt tttctgtccg agccaagaat aaacgttcca tcatcaatgc
    14161 cgtatgcata tagagattta gttttacacg gccatttaaa gtgaaatgat agtaattttc
    14221 atatttagaa atgactgttt ccacttcact catcacgatc gttgggttca gaaagttcaa
    14281 acggtccgca attccttcca acgaaaagaa ttttactagc tcctgaatca agcggttaaa
    14341 ttctgccggc ttcatttcag gactcaaaat atgctccaaa ttggctgctc catcaccgtc
    14401 taagatgtca taaacattaa tattaggaat tgaaaaggaa cgtggaagat ccgaagtcgt
    14461 gatgaccaat tttgtcttgt caaaataagt ttcatcattt tggtcgatta attcacgtag
    14521 ttctctgtag tccttcgtga aaacttcgat ggattcatcc gataaatgat gacgaaaaac
    14581 atctttcaat ttgtccgaaa tccccaaacc cgacatacag gaaatgataa tgttgctact
    14641 ttgagaaaag ccttcaaagt attgaacatt gattgaatac ttgtctgctg catcctccgc
    14701 aatctgttta aatggcgcat tcatcgtcat cttcaagcca atatcaagtg caatggaagt
    14761 cgtcaaatta ttcagaagaa gtaactcccc ttttaaatcg ttcttgatct gtgtgtaaat
    14821 ttgatttaaa gagcccatat ctacgatcag cactagacta tctgtattca cttgccgttt
    14881 cacgaaattc cttgtcgatt cgacaatctc tgacacatta ctctctactg gcatatccaa
    14941 cgcttcaaaa acataattgc cgcataattg attcactact gcttgaatgc tgctagccgt
    15001 actatctccg tgagcaagca acaggccctt cagctcgatg gattcatcta cataatcaga
    15061 taaagtcacg acaataagca gtcttagaaa gttctcgtcc ttttctgaga gcggtggtaa
    15121 atgctccaag aactgattac ataagtaagt cgtccgaggt agatttgcag ctaatgtacg
    15181 atttatcccg gttaagtctg tcttatagct tggggaaatg acataggatc tgctaataat
    15241 ttctgcaaca ggtccactcg tcgtcaatcc gtacgttttt cctaaaacgg atacccagac
    15301 ctttctaaac atctgaatca tcaattttct actcattgat aaaaaagaat ccttatcaat
    15361 gtgatgcacc aaatgctgta cttcattctt tatcgaagaa aaattttcat tgaaattacc
    15421 ttcatttatc agctgagtaa ttttttccaa aatcgaatca taatcaaacg gtttgattcg
    15481 atccgttttt atcttttgat ttttctttat caataaacta gcaatcggca agctttctac
    15541 ttcggattcc agcatattta actgaatcaa gatctcattt ttcccaatcg ttaatggttc
    15601 ttcttgtgtt cgactataca catccgcaca actgatttta atgatattct tcagcttacc
    15661 aatattccca ctaaagggat gagataacat taaagacaag gcttctcttg aaacaataat
    15721 atctttttgt aaaacatccg cttcattttg aaaaaataat tgaatcagct ctaatcgttc
    15781 tcgaatgggg cgatcttcaa aagttggcaa cataacacta atttgaatac gccgatcaaa
    15841 ggtgtctaat aaataatttt cacctttttc cgtcgtggcg aaaataaaac gaaccttagc
    15901 agaatgccaa tttacatttt caccgactgg acgatagttt ccagtatcaa taaatagaaa
    15961 gagcttttct tgattttctt tcgataggcg atggacctca tcgagaaaaa gatagccgtt
    16021 gttggccgtt gccaataaac catcggtatc cttttcagcc cccgtaaagg cccccttctt
    16081 gtatccaaac agtgttgccg aaagcagttc gggattgtcc gcataatcgg cacagtttaa
    16141 gatagcaaat ggtgcatctt tttcaataat ttgctcatgg atagcgtatt caaaaatttt
    16201 tgtggctaaa aaactttttc caacacccgt ggctccattt attaatacac tgagtccgtt
    16261 aggcggatat ttgacagcgg ctatacattt ttgaatgacc tctctcagac ttccgtcatg
    16321 accaactaca gaatgaaagg cttcgtttat ttgctccgta ttatctacaa ccgcatattc
    16381 atctaaaggc ttccacaaaa caggctttcc cggtaatttc tcgacctttt tatcttccac
    16441 taatctcgtc aaataatggc tggcattctg acgagagata cctagattct tcgaaatttt
    16501 ctcggcagtg acagaagaca tattccctgt tagtcgtatc agctcatcaa aaactcgatc
    16561 tttagcgctc tttttcattt tttcctccag tttaatgtgt ctaaaagcat aataaactat
    16621 cggctgcaat atgtctattc tatatttgta ttccaatttt tactttgaaa cacaaatagt
    16681 cgaatatttg cctcagatat ctgacaaaat aatttatcta ccaatttagt ttttatctaa
    16741 tatgattttt atgttttttc atagctacaa atattgaact ggattcatat attagtttta
    16801 ttaatagatt acagaagggt taagtatatt tgcatagttt ccaattactt tatccttctg
    16861 taactttttc aatcttagat ttactagccc gtctcgggcc ctattttaca atggttttgt
    16921 ccacttttct ctggtagaaa aacgtggtag aaaaaataaa ataacacaaa aaaagcggcg
    16981 tttcatccgc ttttggtaga agattggaaa actcagatag aaaaaggacg atttttagct
    17041 ctttagaacg ttgataagtc cccattctta ctgagttttg ccattatctc ctatacatct
    17101 tgaattctaa gaataggtca ttatagatgc ctaggtattt cgatcctaga tctttgtaga
    17161 cttcaagatg ggagatcgtg tcatcagatg gatagaattg ttcgtccgac gaaatgtctt
    17221 ttggcaataa cgcttttgct tcttcatttg gtgtagaata accaatatac tctgcatttt
    17281 gtgccgcatt ttccggttct agcataaagt tgatgaaatc ataggcacct tctttatttt
    17341 tcacggtttt tggcataacg atattatcaa accaaagatt ggatccttct ggtgggatca
    17401 cataatgtaa atgttcattt tcccacatca tatcggcagc ttcgccagaa aatgtcactg
    17461 ccacggaggc ttcttcattg atcatataca ttttgatctc atctgccacg attgctttga
    17521 catttggtgt taaatgattc aatttatttg ctgcttctgt cagctgtgcc atattcttac
    17581 tattcaaaga atagcctaaa ctattcaaag aatagcctaa actattcaaa gaaagcccca
    17641 taacttctcg tgcaccgtca atcagcatca aactgtcttt taattccggc ttccacaaat
    17701 catcccaatg cttaatttga tttgcatcaa agaatttatc gttatatacg atccctaaag
    17761 ttccccaaaa atatggaatc gaatactgat tatctggatc aaaatccaag tctaaaaatc
    17821 gtggatcaat attatttaat cctttgatct tcgaatgatc taatggaagt actagttttt
    17881 ctttgatcat tttttggatc atatattcac ttggtatagc gatgtcgtag tttgtcccac
    17941 cttgctggat ttttgtgaac atcgcttcat tagaatcaaa tgtttcataa ttcactttgt
    18001 atccatattc tttttcaaat ttcgtgatca aactaggatc gatataatct ccccagttat
    18061 agatggtaag tacctttgct ccactcatgc cacttgtttt ttcaagttga cgaacaccaa
    18121 gcagcagcac cgcaataatg atgagaatac ctaaaaacag agattgtaat tttttcatcg
    18181 cagccgtgcc accccctcgc gtactcttct gtttttcttc agccgttttg gacggttttc
    18241 tttactaata aagtagtatc caatgaccaa tatcatggag aacaagaaaa ctaacgcact
    18301 tagcgcattg atttctaaac tgattccttg tcttgcacga gaatagatct ctactgagag
    18361 cgtcgtaaag ccatttcctg tgacgaaaaa tgtaaccgca aaatcatcaa gagaataggt
    18421 aaatgccata aaatatccag ctatgattcc tggagaaaga taaggcaaaa tgatattttt
    18481 gactacttgg aaattattag caccaaggtc tctagccgca tcgaccattg aatcgttcat
    18541 ttcctgcaat tttggcaaga ccatcaagac gacgattgga atgctgaaag caatatggga
    18601 aagcaataca ctctgaaaac ctaatccgaa tcctagtagt gtaaagaaaa tcaagaaact
    18661 agcaccgata ataacatcag gagagactaa taagatgtta ttcatgctca acaacgctgt
    18721 ccgtgcacgt cgttttttcg tgtaatagat tcccatagcc ccaaatgtcc cgatgatcgt
    18781 ggcgatcaat gcagataaga aagccagcat gaacgtattc aatacgataa tgatcaaacg
    18841 tgtatcttca aaaacagctt cataattttc ccaagtaaat cctgtaaagc tgttcatcgt
    18901 tcctccttca ttgaaggaat aaaaaatcag atagaagatc ggtgcatata agaataaaaa
    18961 gacgatccct aaataaagat acgaccattt aaattttttc atttatgagc gacctccttt
    19021 tttcttctcg cctgtcagga gcatcacgat gaacatagca atgattaaaa tcacaccgat
    19081 tgtagaaccc atcccccagt tttgtgtaac caagaaatgc tgttcgatag ccgttcctaa
    19141 agtgatcacc cgatttccgc caatcagacg agtcagcatg aataaagaaa gagaaggaat
    19201 aaatactgct tggacaccac ttttcacacc atttaatgat aacggaaaaa tcactcgtcg
    19261 gaaggtctca aagctattcg cgcctaaatc tctactagca ctgatcaaag aaggattcat
    19321 ctcttccaat gcattgaaaa ttggcataat cataaatgga atctcgatat acgttgccac
    19381 gaacagaaaa ctgaagtctg tgaataatat ctgtttcggc ccgatcccga taaaatcaaa
    19441 gaaatgattc acgctgccgt gcacactgaa aatcccaata aatgcgtaag ctttaagcag
    19501 cagattcacc catgtaggca aaataatcag catcagccat aattgcttgt gcttcagttt
    19561 tgttaaaaaa taagcagtcg ggtaactgat gatcagcgtg aaaaacgtga tcaaaaatgc
    19621 ataccataca gaattgatcg tcatagaaag cgatgtcccc gacgtaaaat aagatagata
    19681 attattcagc gtgaattgcc cattcatatc aaaaaaagat tgataaatga tcattaatac
    19741 aggcgcgatc acgaataaac cgagccacaa aatataaggg acggaataga tcctgcgcat
    19801 tgttttcatt cttgtccccc ctattcttcg tagctgtcaa gacgtgcatc gaattcttct
    19861 tcagactcgt tgaaacgcat gacatggata tcttctggct caaaggccaa tcctactttg
    19921 cttccttctt tagctttttt cgttgaatgg accatccatt cattttgctg ttcatcataa
    19981 cagatgattt cataatggac accacgaaac agctgagtat cgaccgttac gactagtttt
    20041 cctttatctg gtgtcgtgat cgtcaaatcc tctgggcgta aaacaacttc aactggttca
    20101 tttagacgca tcccgccatc gacacattca aattgcttac caacaaactc aactagatta
    20161 tcttcgatca ttacaccgtc cacgatattg ctctccccaa caaaatcagc aacgaaatga
    20221 ttgattggct catcataaat atctacgggt gtaccacttt ggacgatttt ccctttattc
    20281 atgacaaaaa tctcatcact cattgccaac gcttcttctt ggtcatgagt aacaaaaata
    20341 aacgtgattc ctaatcgttg ttgcagatcc cgcagttcat actgcatatc tgtacgtagt
    20401 ttcaaatcaa gcgccgataa cggttcatct aatagcaata ctttcggttc atttacaatt
    20461 gctcgtgcaa tcgctacacg ctgtctttga ccaccagaca tttcactaat ctcccgtttt
    20521 tcgtatccag gaagctggac catacgcaaa gcatctttta ccttcttttc gatatctgat
    20581 ttggacattt tcttgatctt caatccaaaa gcaacgttat caaaaacatt catatgagga
    20641 aaaagtgcat aatcttggaa gactgtattt acttgtcgct tattagctgg caaatcattc
    20701 aaccgtttcc cttcaaaata gatgtcccct tctgtagctt cggtgaatcc agctataata
    20761 cgtaggatcg ttgttttacc acagccggaa ggaccaagca gtgtataaaa ttttccttgt
    20821 tcgatctcaa aacttacttt ttttaatact gtttcatcat catagcgttt cactacttga
    20881 tcaaatgaaa tgattggttt ccccacgttt ttacccccta tattacaaat atgattgcgt
    20941 tgcaacaatc aatacttttg ttcgtttttt gagatgattc cttaattgat gttgttttgt
    21001 cgcttgataa tagatcgact gtcctgcttt tgccacatag accgtctctc ctaagcttaa
    21061 ctctaattcc ccttctaata caaaaataaa cgtttcagat aatgaaggtt caaacgtctt
    21121 atattctcct gcaccttcaa aagtcagcaa gacaggctcc atttcttttt cattcgaatc
    21181 agccacgagc cattccaatt catacccgtt ttcttcatcg aaataaaccg tatgatcttc
    21241 ttttgaataa accacttgca gattcgctgc ttcttgatga aaaaattctt ctggagtcac
    21301 acctaagact tcaagaatag aaaagaatgt ttccattgat ggtgaactta aatctcgttc
    21361 caactgggaa atataccctt ttgacaaatc tgtgcgttcg cctagttctt cttgtgtcaa
    21421 attcttttgg atgcgcaaat ttcttaactt ctcaccaatt tccataattt cctccgaatc
    21481 gaagttttct aatagtaaac ttcctgttta ctaccactcg tattagtata cgaaatttat
    21541 tgaaaaaggc aaccctttgt aaaatttttt ttgctgaata tttctttatc ttttggaata
    21601 aattctagtt gtttgattct ttatttttca cctaattttt gtctaaattt acggaagaac
    21661 aagaataaaa gagtaggctt tatggtatga taaaagaaaa ttttaaaagg agtgtctcac
    21721 gaatgaacgc ttttcgatct tttcaggtaa taaaggaacc tgttttccat acagcaatca
    21781 gtgatctgcc atttactgag ttggctgaaa atgaagtctt ggtaaaaatt gcctattctg
    21841 atgtcaatta taaagatgca ttggcaatga gcgagtctgg tcaggtgata cgaacatatc
    21901 cgatgactcc agggattgat ttatccggaa ctgtcgtcca aagtaacaat ccacgttttt
    21961 caaaagaaga tcttgtactt gctactggtt ttgggcttgg cgtcacccat ccaggcggtt
    22021 atagccaata tcaaaaagta ccaggagact ggttagttcc tctaccaaaa aatatgacgc
    22081 tgcgtcaagc gatgatcctt ggtacagcag ggtttactgc tatgttgtgt gtgaacgctt
    22141 taatccgtca aggtatgacc tccgataaaa aagttgtcgt tactggtgct tctggcggtg
    22201 taggcagtac agcgatagcc ctgttacata aactaggatt ccagtcaatc attacctttt
    22261 ccagaaaaga agagtctgtc acatggctaa aaagtctagg tgctttgcaa gtcgtacgac
    22321 ctgatgaatt tctgccagag acaacaaaag ctttaggaaa acagcaaatc gactatgtca
    22381 tcgacacagt aggtggcgag cagctaagca gtcttcttcc attgatctct tataacggtg
    22441 cagtagcttt atgtggcaat gctgggggaa tcaaactaaa cgcgactgtc ttgcctttta
    22501 ttctgcgaaa catccagttg attggaattg attctgtcaa tgtaccaata gatcaacgtc
    22561 tttctttatg gcaacagatg gcggatttgc agattgcaga tgaactggtc gtccaagaga
    22621 ttactctgga tcaattgcct gaaacagcat ctaaactact tgctggaaca caccaaggaa
    22681 gaacactagt aaatgtaggt gaccataaat gaagattcta atcacagctg gaggaacgac
    22741 tgaaaaaatc gatcaagtac gtgctattac aaatcattcg acaggacgat tagggcaagc
    22801 attagctgat tatttagctg ccaatccgga taccacaatc gattacgtga ctacgaaaca
    22861 agcactgaaa ccgaaaagac actccaatat aacgatttat acgatcgaat ctgcactgga
    22921 cttattttta caattagaag aactaacgaa aaaagaacac tacgatgcga ttatccacag
    22981 tatggcagtc agtgatttta ctcctgcttt tagtttttca gaagaacagc tggcaaaaaa
    23041 cctacccact tcttcaacgc aagaagaact ggacaattgg tttgcggaaa atgaacagac
    23101 agataccact gtttcaaaga tctcttctaa caccgagcat cttgtgctcg ttttgaagaa
    23161 aacaccaaaa atcatttctt atctacgtga atggcagcca aaagcaaaaa tcattggttt
    23221 caaactatta gtagatgtac caaaggaatc tcttctggca gtcgcaaaaa atagtctgat
    23281 aaataacaaa actgatttta ttttcgcaaa tgatttgacg gaaatccatg gcgagacaca
    23341 ccacggctat ctcttatcta aagatggaac agtggaagaa gctcaaagta aatctgagat
    23401 tgctgcattg attactgaga aaattagact ggaggaatca aaatgaaaaa gatcttacta
    23461 ggcgttactg gaagtatttc tgcttacaaa agcgctgatc ttacaagtca attcgtcaaa
    23521 ttaggtgccc aggtagatgt gattatgtct aaaagcagca cacattttat cacgccatta
    23581 accttgcaat ctctgtcgaa gcgcgcagtc catacagacg tcatgcaaga atcaaatccg
    23641 caggtaatca atcatatcga actagcaaaa caagctgact tgtttctcat cgcgcctgct
    23701 acagcaaaca ttatcggcaa gctagcaaac ggcattgcag acgatcttct ttcaacagtc
    23761 gcaatggcgc ttccagtggg aacaccaaaa ttgattgccc ctgccatgaa cacgaatatg
    23821 tatcaaaacc cgatcactca gcgtaatctg gaaacattga gatctgtcgg ctatcaggaa
    23881 attgaaccaa gagaatctct tttagcttgt ggagattttg gaaaaggtgc cttagctgat
    23941 attcagacga tcatcgaaca ggtcatgctg actcttaatg aaagaaatgc ttagaaaaaa
    24001 ggagtactta tgaaaaatac aaaaaacttt acattaactg cgatgttttt agctattttg
    24061 attttattag ctgttacgcc tttaggtttt atccctatcg gtccaatcaa tgcaacaacc
    24121 atgcatattc ctgtaatcat tgcttcgatc gttttaggac caagactagg tgcttttctt
    24181 ggcggtacat ttggactgat cagcatgatc cgtagcacag ttatccaaac acctttgtct
    24241 tttgtctttt ctccgtttat cccagtcatc ggaacagaac atggaagctg gaaagccttg
    24301 ctgatcgcgt ttattcctcg catcttgatt ggggtggttc cttatttcgt ttataaaggt
    24361 ctgcgcaaac taatgaaaca aaaagcagat tccgtttctt tattcttagc tggactttcc
    24421 ggttcattga ccaatacgat tttagtgatg aatatgatct actttttatt ccagcaagat
    24481 tatgccaaag tcatcggaac aaatttaaat gctgtttatt cagctattct agcggttatt
    24541 tttacaagtg gtatacctga aggaatcgtc gcaggtcttg cgactgcagc agtatgcaat
    24601 gtcttgttaa gatacttcaa gcacccttct cttactaact gatagtcatc gtagccgatc
    24661 tctgattttt ttctcttttg gtgttactat tgaatggaaa gatttgacgt cgaaaggatg
    24721 atccaaatga aaatttttgt tgtaggtgca aacggacaaa ttggccgaca cctgataaaa
    24781 gatttagctc caagttccca tgaaattttt gcaggggtga gagatgttgc ttcccaaaca
    24841 ttagtaaaaa aagagaatgt ttcgtatgtc tcttttgatt taacttggtc cgtggaaaaa
    24901 atgaccgaag cattcaaagg catcgatgta ttgatttttg ctgccggctc tcaaggaaag
    24961 aatcttctgc aagtagactt ggatggcgca atcaaaacag tgatcgcagc tgaaaatgcg
    25021 catgtctctc gctatctgat ggtcagtgct gtttatgcag atgaaccagc aaaatggcct
    25081 gagtccatga cagattatta tattactaaa cattatgcag atgaatggct gaaacgaact
    25141 aacttagatt ttgtcattct tcaaccagtc acattgacta acgatgaaga agttacttcc
    25201 attcaattaa ctaagcctaa tgagaaggca tcaaaaacga tcactcgctc tacagttgct
    25261 gctgtacttg ccgctctagt ggaagaaacg gatatttctc gtacgactct agtactttct
    25321 gaaggtagca aagagttgaa tacagcattc caagaatggg caaaggagga atagatccat
    25381 gcgtgccatt tcaatcaagc atcctggttc tgtagatgta ttagaacaaa ttgaagtgcc
    25441 tgttcctaaa ccaaaacaag gcgaattact gatcaaagtc catacagcag ctgtcaatcg
    25501 aacagatatt atgaaaagag aatcagtctc tttgaaacct ccctacccta ttttgggagt
    25561 cgaagtagct ggagaggtag ttgagaataa aagtgatatc tccactttta ctcctgggac
    25621 aaaagtatac ggattagtca atctaggtgg ttatgccgaa tatgctgtga tgcctgccga
    25681 tcgtgcaatc cttctccctg atacgctaga ctatgtttct gctgctggaa tctcagaagt
    25741 ttttttgact gcttatcaaa cactttactg gcttggaaaa ttacaagaag gcgaaactgt
    25801 cttgatccat gcaggagcaa gtggtgtggg aacagcagcg atccaattag ctagacagct
    25861 ttctcacgcg aaaatcatcg ttactgcagg atcagaagaa aaactcgcct tttgtaaaga
    25921 acttggtgca gatgaattga tcaactataa aaaacaagac tttcaagaag aggtacgaaa
    25981 aatcactgaa ggtcggggag tcgatgttat tttggatttc atcggcgctt cttactggga
    26041 aaagaattta gcttctatag ccgttgatgg acgttgggtc ttgattggta tgctaggtgg
    26101 gaccatcgtg cctgagatag accttggtgt attgattggg aaacgtgtcc aactgcttgg
    26161 tacattattg acacctagaa gtgatcagta taaagcagag ctcgcacaaa cttttatgca
    26221 aaaagctggg ccttttctag aaaatggcaa gattcggcca atcattgacc gtacattcca
    26281 attcagcgca gtcaaacaag cgcatgaata tatggaagca aacaaaaaca tcggaaaaat
    26341 cattttgaag ataactgaat aaaatcatgc tgatcaaaaa agaggctggg acagaagcgt
    26401 ttaactccaa gaaataagaa gaaattcacg aaaattgctt ttcaaatttt tgtgaatttc
    26461 agcttatttc cgaaggaatt tcttctgctt ccgccgttta tacgtgttta gagcgtgaga
    26521 caaaagtgtt ctttactttt gtcccacgct ctttttccga ataaacggtg ttcaaaagct
    26581 tgcatctgcg gtaataagtc caaccaagtt aaaaacataa gaagctgttt ttacttggct
    26641 gttcttatta cttgatgcag ggcagctttt tcacaacctc ttcactaaac agtgttcaat
    26701 cagctgaccc tcggtattag ctcaaaacgc tgatttcaca acctcttttt atttacgttc
    26761 tatttcattc attttccgaa gcaaatcgag ctgcttgtat gcccgcttgt cgcccaaaaa
    26821 taatgatctc cgcaactgaa tttccaccga tccggttgtt tccatgtaag ccacctgtga
    26881 cttcaccagc agcatataac cccctaattg gctggttttc tttatctaat acttcagtgt
    26941 tcgtattgat tttcacaccg cccatcgtgt aatggattcc tggtgcgatt ttgatcgcat
    27001 aataattcgg agacgataag tcatgttcca tggctgtggc acggttgaat tgagcatctt
    27061 ttttctccgc aacatccgta ttccatccat caactgtttt tgctagtgtt tcttttggta
    27121 aatcgatttt ttctgctaat tcttccattg tctttccagt tgtgacatat cctttttggt
    27181 cataaaattc aatagctgtg gcacgatcac gcacgccttg gtcaaaaatc aaataagctg
    27241 atttttcagg caatgctgta attgctgcag atactttatc ccttgtatcc atttcattga
    27301 caaatctttt cccctcttga tcgaccaaga ttgctccttc tccgcgaaca acctcaccaa
    27361 tcaagacccc ctcatcctgc tgcacagttg gatgaatttg tattttatcc atatcaacgg
    27421 tttgtccacc taatttttca atcatggtga taccatctcc agttgatcct tcttgatttg
    27481 tcgtaatata atcagctaaa tcgggacgat atttttcaat aaattctttg ctggcaccaa
    27541 aaccgcctgt ggtaactacg attgcttttc cggtgacctc ttttggttct tctccttgaa
    27601 catgtacagt cacttcattg accgtttccc catttttctt aatgtctgtc acatctgcgt
    27661 tgacaaaaat agggatttcc cgctcatgga cgttattcaa taacccctcc actaagtatc
    27721 caccaatagc cgagccatca gacggacgat gtgtcctctt ttcactcatc cctccagtga
    27781 tcgttaagtt gtccagtttg ataccgtttt gatctagcca atcgaccgca tcagcagagt
    27841 gatcgacaaa gtatcgaagc atttctttat cattcgttcc tccaccacct tttagcgttt
    27901 cttcatagaa ggcatcattc gagtctttga ttccttcttc tttttgaaat tttgtttctg
    27961 aagcattcat accgcttgat gatttagatg tgtttcctcc ggcaacaggc atcttttcca
    28021 aaattactgg attcaaccca gcatcttttg cttcgatagc tgctgccatc cctgcaccac
    28081 cagctccaat aatcacgaca tcataagatt ctttcatttc ttttggatct gtatatactt
    28141 gttcagaagc gcctgatgat acttcggcag attccttcgt actagaactt gtctgcgctg
    28201 tatttttctg atctgcgccg catgcgctca tagcaagaag tgcaacggct gttaataaac
    28261 cagcaactaa ttttttcatt tgtatccccc ttttctcctt atactatatt aagtgatttt
    28321 tttcacaata tcaactctgt ttttctttaa gtcatatagc tttggtaaac acacgcttct
    28381 tagtataatt aaggatatac atgaaggagt tattttatga atcatttgaa aacctttttt
    28441 acgaacagta caaaaactgc aggtagaatc acaaacggaa tctatatttt attacgtatc
    28501 atcgtcgtta ttatgctagt ggatcaggtc tggaaccaac actggggaaa tacaatgctt
    28561 ttattactga cattaatttt atttgaaatc ccttattttc tggaaaagat attaaagata
    28621 cagattccaa atatgctaga aatcattttg ttatctttta tttttagttc aacagtttta
    28681 ggagagttaa gtgattttta tggctatttt tcaatgtggg atacttttct acatgcattc
    28741 agcggatttt tagctggggg tgtcggcttt tcccttgttt atttgctcaa taaaaataca
    28801 aaaaccatga acttgactcc tttattacta gcagttgttt ccttctgttt ttcgatgaca
    28861 gttggtgtta tgtgggagtt tgtggaattt tcagcagata aattactgca attcgatatg
    28921 caaaaagata cgatcatcca gcaaatcaat agtgtggagt taagtaaaga cggaaacact
    28981 gtctatcatg ttccagatat cactcggaca atcattgaaa gtcaaaatgc agatggtaaa
    29041 acagataaaa caatcatcca aaatggttac ttagacgtgg gaatcatgga tactatgaag
    29101 gatttatttg ttaattttat tggagcagtt gttttcagtg tatttggtta cctctatagt
    29161 cgaaacgatt accaaaaatt tacgttcatc aagaatttta ttcctaaaaa aatcaaacga
    29221 taaaacatgc taaaaaacaa gagaaggggc agtgacaata cttttgtcac tgccccttct
    29281 tttttgaatg tatggcatgc cattagttat ccgatagtat taactcaaaa aagtaagata
    29341 tgaggaatga ctatttcgtt ttttatccca atactgagga cttatttcac catttcgtta
    29401 tttatctaat ttacttaaaa cctgcataac tttttcataa tctggattag gtgtgccgtc
    29461 tagattttca gcaataaaag taaaacccat ttttttataa agagcaatcg cctgatggct
    29521 ccatgtctgt gtgtgaagat agattggtcc gtccgtatgg agggtaggaa attcttgcaa
    29581 gactctggca gtcaatgctt ttgcgagccc ttttccttgg taatctggtt tcactgctaa
    29641 ccaatgaaaa accggataca cttgctctct tgattttttt cgccaagcgg tacaggttgc
    29701 tactttttct cctttttttg tctctacaaa aaacatcctt ctttcaagtt cttcaggata
    29761 aggagcaaag ttttgttgaa aatactcaag tgcttcatct gtcgtttgaa attccccaac
    29821 ggaagtctca atctccgccc aagcagattc atcttctttt tgataaaatc gaaattcaaa
    29881 accttccgct aaaggcgtga ttggaacatt ttgttgaagt ggtcttgtca tccagatttc
    29941 tgcgtaaggt aacgttttat ctaacatttt tctatccctc ctcgtctcca ttatgccaaa
    30001 taacatatga ctcagctact tatttgacta taacagatag agatataaat cagaaccagt
    30061 catctgcgtc aaattcattt cgattagcgt atacccatgt tcctgccata cctcgcatga
    30121 aatctcctaa agcagaagaa ggaatacctc caccaggtgc gggtgttccc ggactaggaa
    30181 gtggtacttg cggctgcaga tgctcatcgg tggaatcaat agttgacaag cgttttttct
    30241 tcgtttcctt ctggtcatct gattccttct gatcttccga ctgtttagca acaaattctt
    30301 tttctgattg ttgttttatt ttaggctcta aaatttcatt ttccaatcca gaaacttgtg
    30361 gggccaaatg agcttcttgc cttatcgttt tattagattc tgagattttt ctagatattc
    30421 ttgctaactc taggcttctt gtttgtttta ctttccctgt tggagaaact gcatgagcca
    30481 tttgttgttt tttttctgac aagctttctt cttgtctttt ttgttctttt tgatctatct
    30541 gtttgtttaa tggtaaaaca tgtaatagtg actgagcatg gagttcttgg agtgaatacg
    30601 ggtcatgata actatacata atcgtaaaat cacctgtttg tttggtcaaa taaccatcct
    30661 ccaatggtac ttcattgatt gtaaccgata catcctttaa cggtacgggt ttacctaagg
    30721 aatttgttgc tgattggatc aactcttctt tgtttatttt ttcgtttgga tgaacaataa
    30781 gatcatgacc ttctaatgaa cgattgtctg gtatataaac ataagtaaag gtaatttccc
    30841 ctcctgattg cttcctatta ttcatcagtt ctgagtgaag tacttcaagg atctccgacc
    30901 agtgactttt tctgtctaat ccgtttgctt gcatccaatc agaaatagaa gtgactttcc
    30961 cattttgttc ataagtcgat aaatctatat ttggcactcg atcagaaaat tcagcaggta
    31021 ggcgcaaatc aggaatacga tttacactac tcatatgtgt ttctgcttga agttctttat
    31081 ttgtttgact atctataaaa tgagtgatga cagtcgatga agcagcagat gcttctacat
    31141 aaactacagc tgttgtttct gccacatttg atgttttcga gtctatataa gttaatacaa
    31201 cgggatattc tcccggagtt gtagtatcta ctgtcccgtt cattttgatt tcttctttat
    31261 ttcctgaagt tccatcgctt tttgttacat attcaacaag atctttaggg gcgtaactct
    31321 ctcctgttct taagtgaaga tcttttcctt tgatagctgt ttgatcagca cgaacatgga
    31381 tcacagcaga tgcagtcatt gtttttaaag caattggatc aaaataggac aaggaaatag
    31441 tagatgttcc tgtattagtc gtatccacga tattcccatt gtttgaaatt actttggaca
    31501 tatctccttg tgttccatct gcgttcttca gcctttctac cagatcagat atcgaaactt
    31561 ttgtccctgc cagaacatcg attttctttc tttcaaactg tgaataatct ttttcatata
    31621 cataagaaac ttgtgcgctt ccaccgtcct ttatatctgt caaagcatga ttcaaaatat
    31681 cagtgatctg ttttaactga tcaccttttg taggatcagt catatcggaa aagatagaaa
    31741 gcggcacact gcttccggtt tccgatgtcc ataatgtttt gttaggaatt aaccagtagt
    31801 ggtttatcgt tggaggataa ctgactttat tataggaagt caatgcagga agtagctgtt
    31861 ttccatttgc atcagtgaaa gtatgagtaa tagtgatagg ggaatcagtg gtctcagaaa
    31921 cagaggtacg tacgaccttg atggtttgtg tcgttgcctg aacgggtaca tgcatataga
    31981 cacctacaga taaactgatc agcatcgtgc gcatcataaa cttaacgtag tgtttttcag
    32041 aacacgaccg ttccttatct aaacgacaag cgtgtttatt tagttgtttt gaacgtcttt
    32101 ttgaacacat ttattcttag tcctccctac tcttgtctaa acatgaagta gtaattttca
    32161 taagatgatt tcattatata aataaaatca aaagaagatg gactattagg agagtatttt
    32221 ttttgatttt ttattgtttc aagaaaatcg gaataataac ttatgtactt tttaattttg
    32281 ttaagtaata tatctagtta tatctagtta tatctagtta ccttttcttt gaaaaaaaca
    32341 taaatcagct aataaatatg tgagacaaag ctgccatcca taaatactag ctgatttttt
    32401 cagttaaatg tctatttttt tctctgatga tggtatttcc aaaatattcc cagtcatctg
    32461 gagtcggtgg atttttccaa attatctgtt ctttattaaa tttttcaagt aaacaatcag
    32521 ataaataaat attcgtacga gaagtgattc gactctcaat cacaatattg taatttttaa
    32581 atcctttcac ttgagaaata atgtaatcgg tataagcaga tccttgcgaa aaatcaatac
    32641 agacatgaat cggtgcttca aaatatgata ccggacaaat accgaccaat aaaaagagat
    32701 aatcataaaa taagcgaatc atgaaacgtt catcttttcc caagaaatag cgtttattct
    32761 cttgtatgac cttttggatt gctgtactga atattggata cgtctcgaag aaaaactgta
    32821 gctgcttttt agacgtaaag ctagtcatct caaagtcgaa tatccaattt tttcgattga
    32881 catgcatcat acccatacga agttcttttc gtatatatag tctttcttct tcagagattt
    32941 caatcgaaaa tggtaattga tcaatcaatt ccactgacat tttttgacta atcatgtgga
    33001 tatcatgaaa atgagcttcc gcaagtccaa atgcgccatc taattcaaat tcttcttccg
    33061 tgatcaaaaa caacatgata taagaaatct catcaatgat ctgctcttta gggatatgaa
    33121 gaaaagaaat atgtgataaa tccttgatga tcttcattcc ttctgagctc ttaaagtatt
    33181 catctgaaaa gaaacgtttt ccgattggtt gattcccata ggccctcaac aaactaatag
    33241 tggttagcaa attgaatttg attcgttttg ttgcagacag ttttaaattg aacagatatt
    33301 caaaatattg cacgatactc tttgcttcat tcatgacgct ttctctaaat ggcatagaaa
    33361 aaccattaaa gaccccgaaa tataccccaa ataatacgtt ccgtatgttt atttcttccc
    33421 caactaatat gtttttcttt aactttattt gatgctgttc aagaaaagag actaattctc
    33481 ttctttttac ataggctctt gatatgctta aaaaatgatt ctctgcaaat ttttcgatcg
    33541 ttacttttga atccacgatc tccgttaaca gtcgagcaat ttttgatcgt tgaaagtaga
    33601 ttcttcttaa atttttgata tccgtcaaat tcagacgttc gacatggatc tctgcttctt
    33661 ctgaaatttg gatctctggc tttgttttga attcagtaaa ttctttattt aattctatga
    33721 tataatttct tgttttaaat ttagacaaac ctaatgtttc atataactta ggcagcacta
    33781 cataattctt tttctcaaat tctaaatatc tagctagcag cagtttttct ctatcttcct
    33841 cttctataag gtaatccaac ttcatatcct acacctcaaa aaatgcctca taccaattac
    33901 ttgatatgca gatgaaagtt catcttttca cctatactga ttttatgatg gattatgctt
    33961 gttttttcat cagttattct cattttttat cttttttttg agaatattgc aaaaaatgga
    34021 aaaatttatg aggaaatatt ctatattttt tgttttattg tgttaaaatg tacaagattt
    34081 gcgccatttg cgtaaacaac cacaaaaaag agcaggacgg ccaccgtcct gctctttta
//
LOCUS       DAZKKZ010000030        34092 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.030, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000030 DAZKKZ010000000
VERSION     DAZKKZ010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 34092)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34092)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34092
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.030"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(114..2054)
                     /gene="thrS"
                     /locus_tag="ACG8LA_001482"
     CDS             complement(114..2054)
                     /gene="thrS"
                     /locus_tag="ACG8LA_001482"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004829 - threonine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006435 - threonyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HFQ0203787.1"
                     /translation="MIKITFPDGAVKEFESGTTTLAIAESISKSLAKKALAGKVNGKL
                     VDLTRPIEEDASIEIITPDHEDALGLVRHSAAHLMAQAMRRLYPNIHFGVGPAIDSGF
                     YYDTDNGQNQVTAEDLPAIEAEMMKIVKENLPIERRVLSKQEALEIFASDPYKVELIS
                     ELPEEEVITAYQQGEFIDLCRGPHVPSTGRIQVFKLLSVAGAYWRGNSNNQMMQRVYG
                     TAFFDKKALKEYIRLREEAKERDHRKLGKELDLFMVSPEVGSGLPFWLPKGATIRRTI
                     ERYIVDKEVSLGYQHVYTPIMGDVELYKTSGHWDHYQEDMFPPMDMGDGEMLVLRPMN
                     CPHHMMVYKNTIHSYRELPIRIAELGMMHRYEKSGALSGLQRVREMTLNDGHTFVRPD
                     QIKDEFKRTLELMVAVYADFNITDYRFRLSYRDPNNTDKYFDDDAMWEKAQAMLKAAM
                     DELELDYFEAEGEAAFYGPKLDVQVKTALGTEETLSTIQLDFLLPERFDLTYVGEDGE
                     NTHRPVVIHRGIVSTMERFVAYLTEVYKGAFPTWLAPIQATIIPVSVDAHGDYAYEIK
                     ERLQMKGLRVEVDDRNEKMGYKIRASQTQKIPYQLVVGDKELEDATVNVRRYGSKETA
                     VEDLNIFIDAMEAEVKNYSREN"
     gene            complement(2391..2570)
                     /locus_tag="ACG8LA_001483"
     CDS             complement(2391..2570)
                     /locus_tag="ACG8LA_001483"
                     /EC_number="5.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016862 - intramolecular oxidoreductase
                     activity, interconverting keto- and enol-groups [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxymuconate tautomerase"
                     /protein_id="HFQ0203788.1"
                     /translation="MPFVHVELVEGRSPEQLENMMKDITEAVHKNTQAPKEHIHVIIN
                     EMKKGTYGVNGEWKK"
     gene            complement(2617..4440)
                     /locus_tag="ACG8LA_001484"
     CDS             complement(2617..4440)
                     /locus_tag="ACG8LA_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HFQ0203789.1"
                     /translation="MTHFKKFLLTLLIGGIALLSEFVFHQPALAFAIVAFTGGILAFL
                     MFLEMIKTLRSGRYGVDVLAITAILATLAVKEYWASLMILIMLTGGDSLEDYANKRAG
                     KELQSLLDNTPRIAHRFKEGKLQDIVIDEINIDDQLLVKPGELVPADGRVTKGESSVD
                     ESSLTGESRPETKKPGDQIMSGSLNGDGSIQMIAEKRAADSQYQMIIKLVEESKEKPA
                     RFVRLADRYAVPFTLIAYLIGGISWWFSKDPLRFAEVLVVASPCPLILAAPIALVAGM
                     SRSSKNGIVVKTGTTIEKLARTKTIAFDKTGTLTKGILEVEAIQPVNGIKKEELLLYA
                     ASAEQESSHILARSLVNNVKNSQLYPVSQLKEVTGQGIQAVVNNHEVKIGRASFVSAE
                     EIETSNTAIYVTIDRSFAGTILFSDQIRPEAAKTIKELRKLDVKNLMMITGDGSAIAQ
                     TIAEKVQLDSVHARSLPQDKLTILESIPKDQRPVAMVGDGVNDAPALAAADIGIAMGA
                     HGSTAASESADAVILKDDLLRVAKAVVISRDTMRIAKQSVLIGIFICIFLMLIASTGL
                     IPALFGAVLQEVVDTVSILSALRAKKDPAIFPDSVPKTNIV"
     gene            4718..6997
                     /gene="helD"
                     /locus_tag="ACG8LA_001485"
     CDS             4718..6997
                     /gene="helD"
                     /locus_tag="ACG8LA_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase recycling motor HelD"
                     /protein_id="HFQ0203790.1"
                     /translation="MNEKQLEQTHVDETIELIQIEQNMLDTKQQELTQEMNHSTKDTA
                     NHKIRAGSNEAFYESAVEYRQHEQELLLKYHTLEAQQKRLQTLSVMKDSPYFARIDFK
                     EDRETETLYLGIASLRDLAEETIVIDWRAPIANLYYEGEIGPAFYETETDRIDVDLQL
                     KRQFKIQEGRILSMVDTSEVINDDFLLEILDESSSNHMKNIVSTIQKAQNAIIRDTTS
                     KVMLIEGIAGSGKTSALLQRIAFLLYHNRKWLEAENVLLFSPNHLFSDYISTVLPSLG
                     ESGVPTQTFKNYLVQLLPEFSLLDEQQQESGFLLGEKDPIQVMKSGLTLVDQIDRYIQ
                     GITNYGPLFRDMKINGRTILSKESIRQWYKETNEQLPLHHRLSLLQTKLLKKLGGLQK
                     DETRQQWVKDLAEEQLQELYATDPNLEYTEQKERSLRKKLANQIVRKRFRRIHRGIMN
                     YQFVNITKQYLHFLQTVPLSLLTRHKISETRWQEHLTTVRTHLRQRELRQEDAVLFFL
                     LMRRTYPVTVTHKARYIFIDEMQDFAPSQVALLQALFPKANLTFCGDLNQNVFGNETI
                     VGSLEDLFVDREVTRFQLTTSYRSTKEITDFANHFIVKEHQVETTARKGDLPLLIQGT
                     TDDIKLNWLADTIRTTQGKARYWRTAIIAKTQEECEALYAQLPDELKQQVQLILNESD
                     FMKRSIILLPAFLAKGLEFDRVFLWDVDAEHFSSQQDKLILYTMCTRAMHELTLFTSN
                     NESPLLNNMDISSYEKKVL"
     gene            complement(7090..7737)
                     /locus_tag="ACG8LA_001486"
     CDS             complement(7090..7737)
                     /locus_tag="ACG8LA_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0203791.1"
                     /translation="MEAKITLEPFERILSGYRKVEELAVNVTDCSKLAQKYARFGVEG
                     YRLGNYVGTGYLNRYLECMVDRAPMLIYRQNYLIPLLFRRSDSAFRLFEEEYRMEAFF
                     LLLEWSLKHRPEKILIERNEKIDTKKNKVIDSAYLAFRVSEILDCGGYPISNFQSIDQ
                     FIEWNRIYRLIDNGGIGRHSKVFDPEYPENMEELKMIISLVKLKYPETDLDLYIE"
     gene            complement(7916..8635)
                     /locus_tag="ACG8LA_001487"
     CDS             complement(7916..8635)
                     /locus_tag="ACG8LA_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFQ0203792.1"
                     /translation="MGRKWANIVAKKTAKDANNSRIYAKFGIEIYAAAKSGDPDPHAN
                     QKLRFVIDRAKTYNVPKHIIDRAIEKAKGAGDETYSELRYEGFGPSGSMVIVDTLTNN
                     VNRTAADVRAAFGKNGGNMGVSGAVSYMFDNTAIFAFAGEDADEILEYLMEKDIDVRD
                     VMEEEGQIIVYGEVADFHSIQEALKEKGITDFSIAEIQMIPQNEVTLSPEDQETFEKM
                     IDALEDLEDVQHVFHNVALED"
     gene            complement(8766..9917)
                     /locus_tag="ACG8LA_001488"
     CDS             complement(8766..9917)
                     /locus_tag="ACG8LA_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HFQ0203793.1"
                     /translation="MKSCGIIVEYNPFHNGHRYHVEMARKITGAEVVIAVMSGNFLQR
                     GEPAIIDKWHRANEALQNGVDLVVELPVEWAVQSADYFAKGAVKILQTLDCDSLCFGT
                     EEETSFDYSSFGRFVQENQDRIEEAFQELSDQTYSYPQKMTEVFRSLYPDITLDFSSP
                     NHILGLSYAKENAKYVHPMELHPIRRKSAGYHEKIITDQRIASATAIRHALEEGKRIA
                     GLVPPQTEEDLSTCSLQTWESYWPYLRYRLLSSTLLELTDIYQMTEGIESRMKTAAAT
                     ADSFEDFVSKVKTKRYTWTRIQRLSCYVLLNIKKQEIPVQQNKNYLRLLGFTDAGRRF
                     LKEKKEISIYSRIGKKEAQEAELLVRSDQIYQLGGNIPEQNFGQIPIRV"
     gene            complement(10134..10874)
                     /locus_tag="ACG8LA_001489"
     CDS             complement(10134..10874)
                     /locus_tag="ACG8LA_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFQ0203794.1"
                     /translation="MAYETFAFIYDEVMDETLYQQWLAFSKRHLQEDTKNILELACGT
                     GALAVAFAKDGYKVTGLDLSEEMLMIASQRAYEEDASIQFVEGNMLDLSEIGQYQAIT
                     CFSDSLCYMKNRQEVQQVFDEVYQALEENGRFLFDVHSTYQVDEVFPEYSYHYQGDNF
                     AFLWDSYPGSEKHSIEHFLTFFVEEQEGSGRFIREDELHQERTYPLESYLRMLENSGF
                     SKVEAFSDFTDEAASEKSKRWFFVAYKD"
     gene            complement(10878..11201)
                     /gene="rsfS"
                     /locus_tag="ACG8LA_001490"
     CDS             complement(10878..11201)
                     /gene="rsfS"
                     /locus_tag="ACG8LA_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0017148 - negative regulation of
                     translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HFQ0203795.1"
                     /translation="MEAADSKRAEDIIALDVRNVSLLADYFMICSANSERQINAITEE
                     IIDKEEENKYEVKRIEGKEGGKWVLIDLGDVIVHVFHAPERNFYNLEKLWSDAPLVDL
                     SEWLD"
     gene            complement(11258..11851)
                     /gene="yqeK"
                     /locus_tag="ACG8LA_001491"
     CDS             complement(11258..11851)
                     /gene="yqeK"
                     /locus_tag="ACG8LA_001491"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HFQ0203796.1"
                     /translation="MNMDYSNEYTAYSRENLMQKIQMRMSEQRFKHVLGVEETAVALA
                     KKYGASPEKASIAALTHDYAKERPDEEFKMVIVRDGFDPELLNYNNAIWHGLVGASFV
                     ERELGITDAEILHAIRVHTTGAAKMSLLDKIIYVADYIEPGRDFPGVQDARAIAWADL
                     DEAVAFETKHTLAHLLAQEQQIYPKTIETYNYWVAKK"
     gene            complement(11835..12485)
                     /locus_tag="ACG8LA_001492"
     CDS             complement(11835..12485)
                     /locus_tag="ACG8LA_001492"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HFQ0203797.1"
                     /translation="MMNTQAKTFVRSQLFPEEMPQFLEKKKQVGILGGTFNPVHLAHL
                     VMAEQAGRNLGLDRVFLMPSYQPPHVDEKQTIDAKHRLNMLELAVEDNPFLQIETIEL
                     ARGGKSYTYDTMKELTQNNPDTDYYFIIGGDMVEYLPKWYKIDELTSMVNFVGIRRPG
                     YTTDTPYPVIWVDVPEIDISSTKIRQKIKEGCSIRYLVPDKVIDYIQNEGLYEYGL"
     gene            complement(12495..12806)
                     /gene="yhbY"
                     /locus_tag="ACG8LA_001493"
     CDS             complement(12495..12806)
                     /gene="yhbY"
                     /locus_tag="ACG8LA_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HFQ0203798.1"
                     /translation="MSLRGKQKRFLRSKAHHLQPIFQIGKGGINSAMIVQIEEALEKR
                     ELIKVSLLQNTDEIAEEAAQVLEKEIDCEIVQIIGRVIVLYKPSTKEKYQRLSKEVKA
                     I"
     gene            complement(12822..13931)
                     /gene="yqeH"
                     /locus_tag="ACG8LA_001494"
     CDS             complement(12822..13931)
                     /gene="yqeH"
                     /locus_tag="ACG8LA_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HFQ0203799.1"
                     /translation="MTEELQCIGCGAVIQTNKPGELGYTPQTALEKGLASGEVYCQRC
                     FRLRHYNETQDVSLTDDDFLRLLNELGQKDALIVNVVDIFDFNGSLIPGLHRFVGDNP
                     VLLVGNKVDILPKSLKKTKLTQWMKERAYEAGIRPVDVLLTSAKKSHEMTELLEKIEE
                     YRDGRDVYIVGVTNVGKSTLINQIIKNTAGVQDVITTSQFPGTTLDKIEIPLDDGHFL
                     IDTPGIIHRHQMAHYLGKKDLRIIAPLKEIKPKVYQLNEGQTLFLGGLARFDFISGNR
                     ASFIAYVSNDVNIHRTKLEKADEFYQKHVGGLLQPPRPDEVEAFPELVRFEFSVKEKT
                     DIVFAGLGWITVTAPVVIAGWAPKGVDVLKRKALI"
     gene            complement(13928..14455)
                     /locus_tag="ACG8LA_001495"
     CDS             complement(13928..14455)
                     /locus_tag="ACG8LA_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008962 - phosphatidylglycerophosphatase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HFQ0203800.1"
                     /translation="MFSNYKPTWMVEAIYQITPAQLKNLGIKAVLTDLDNTLIAWNNP
                     DGTEELLTWILEMKNAGIPVVVVSNNNSKRVARAIEKFDLLYVARAMKPLARGINIAK
                     KQLDLADDEIVMVGDQIMTDIRGANRAGIRSILVKPIIATDSWKTQFNRFWEKRIMAY
                     LLAKHPDMGWRGGIE"
     gene            complement(14635..15420)
                     /locus_tag="ACG8LA_001496"
     CDS             complement(14635..15420)
                     /locus_tag="ACG8LA_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HFQ0203801.1"
                     /translation="MDKTAHDVVQLARAKERWTSLDFFEEIFDSFEECHGDRLFADDE
                     AIVGGIARLDGKPVTVIGIQKGRDLQENIRRNFGSPHPEGYRKALRLMKQAEKFNRPV
                     ITLINTAGAYCGVGAEERGEGEAIARNLLEMSDLKVPIIAIIIGEGGSGGALALGLAD
                     EVWMLEETIYAVLSPEGFASILWKDGSRAAEAAELMKITAPELRELGIVDRVIPETFN
                     GEQLPRYKVAHIMKKALIERLTELVRLDQHKLLEKRYKRFRQY"
     gene            complement(15413..16282)
                     /gene="accD"
                     /locus_tag="ACG8LA_001497"
     CDS             complement(15413..16282)
                     /gene="accD"
                     /locus_tag="ACG8LA_001497"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase, carboxyltransferase
                     subunit beta"
                     /protein_id="HFQ0203802.1"
                     /translation="MALFKKKKYIRINPNRESKPANSPSVPDNMWAKCPNCKHILYTK
                     DIGEEKVCPHCGYAFRIGAWQRLALIIDEKSFEEWDTDLVTKDPLAFPEYTEKIKKMQ
                     DKTGLHEAVLTGKATIQGIPFIIGVMDPNFIMGSMGTIVGEKITRLFERATKESLPVV
                     LFTASGGARMQEGIFSLMQMAKISAAVKRHSNEGLFYLTVLTDPTTGGVTASFAMEGD
                     IILAEPQSLIGFAGRRVIEQTIKQELPEDFQKAEFLLSHGFVDQIVPRMELKQKIHTL
                     LELHTQKGWIDRG"
     gene            complement(16283..17662)
                     /locus_tag="ACG8LA_001498"
     CDS             complement(16283..17662)
                     /locus_tag="ACG8LA_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HFQ0203803.1"
                     /translation="MFSKVLIANRGEIAVRIIRACRELGIQTVAIYSEADAEALHTQL
                     ADEAICIGPAKAVDSYLNVQEVLSAAIVTKAEAIHPGFGFLSENSRFASMCEECNITF
                     IGPKSATIDAMGNKINARQLMQEANVPVIPGSTGVLSTVEEALEIADRIGYPVMLKAA
                     AGGGGKGIRKVQSKEELPQHFSSAQQEAAAAFGNDDMYLEKIIYPARHIEVQILGDRF
                     GHVIHLGERDCSLQRNNQKVLEESPSVVISQTKREALGDAAVRAAKAVNYENAGTIEF
                     LMDEEGDFYFMEMNTRIQVEHPVTEMVTGIDLVKKQVEIAAGEPLNVCQEEVVFQGHA
                     IECRINAENPAFHFAPSPGKIQNLLLPAGGMGLRVDSAVYPGYTIPPYYDSMIAKIIV
                     HGNTRFEALMKMQRALSEFITEGIITNAEFQMDLISHPAVIAGDYSTAFLQEEFLPNW
                     TPETEIGGA"
     gene            complement(17670..18089)
                     /gene="fabZ"
                     /locus_tag="ACG8LA_001499"
     CDS             complement(17670..18089)
                     /gene="fabZ"
                     /locus_tag="ACG8LA_001499"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HFQ0203804.1"
                     /translation="MNIQEIKEIIPHRYPMLLIDRVEEMVEGERIVAKKNVTINEPFF
                     QGHFPEEPVMPGVLIVEAMAQAGAVALLSLEQFKGKTAYFGGLDKAKFRKKVTPGDTL
                     YLEVEILKVKASAGIGKGIAKVDGKKVAEAELTFMIG"
     gene            complement(18114..18590)
                     /gene="accB"
                     /locus_tag="ACG8LA_001500"
     CDS             complement(18114..18590)
                     /gene="accB"
                     /locus_tag="ACG8LA_001500"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HFQ0203805.1"
                     /translation="MDINEIRELVSQFDQSSLTEFDLREGQFELYMNKNKTSRGMNMV
                     QTNETLPVSEPVNVIPEQATTAPEIMKEKESAVFDGIEVVSPIVGIVYLQPAPDKPAF
                     KKVGDQVAKGEVICIIEAMKLMNEITSEADGVITEILVENESVVEYGQPLFRIQQK"
     gene            complement(18593..19828)
                     /gene="fabF"
                     /locus_tag="ACG8LA_001501"
     CDS             complement(18593..19828)
                     /gene="fabF"
                     /locus_tag="ACG8LA_001501"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HFQ0203806.1"
                     /translation="MNRVVITGYGVTSPIGNDADSFLNSLKEGTNGIAPITKFDASET
                     GITLAGEVKDFPYDKYFIKKDSKRMDMFSIYGIYAALEAMEMSGLDKEKMNQDRFGVI
                     IGSGIGGLPTIENQVIRLHEKGAKRVSPMFVPMAIANMAAGNIALRVGAKGICTAIVT
                     ACASGTNSIGEAFRNIKHGYSDVILAGGTEATICEMGIAGFAALTALSESTDPNRGSI
                     PFDENRNGFVMGEGAGVLVLESLEHAQARGAKIYGEIVGYGANCDAYHMTAPTPDGSG
                     ASKAMKLAMEEAGVQPEQVGYINAHGTSTPANDQAEAKAIQIALGENFRDTYVSSTKS
                     MTGHLLGAAGGIEALATLLALEHQFIPPTINVEKQDPEIDLTVVKNESKPASFTYAMS
                     NSLGFGGHNAVLCMKRWEE"
     gene            complement(19847..20584)
                     /gene="fabG"
                     /locus_tag="ACG8LA_001502"
     CDS             complement(19847..20584)
                     /gene="fabG"
                     /locus_tag="ACG8LA_001502"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004316 - 3-oxoacyl-[acyl-carrier-protein]
                     reductase (NADPH) activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HFQ0203807.1"
                     /translation="MDVKGKNVFITGSTRGIGKAMALAFAKAGANIILNGRGEIPKEK
                     IEEIEAFGVKCVGVSGDISDYEKAGQMIKEAEEKLGSIHVLVNNAGITNDKLVMRMDA
                     EDFKKCLDINLIGTFNMTQHVLKKMMKQREGAIINLSSVSGLIGNIGQANYAASKAGV
                     VGLTKSVAREAATRGITCNAIAPGFITTDMTEVLADKVKEQAEKQIPMQRFGQVEDIA
                     QTAVFLAQNPYITGQVINVDGGLVMHG"
     gene            complement(20596..21513)
                     /gene="fabD"
                     /locus_tag="ACG8LA_001503"
     CDS             complement(20596..21513)
                     /gene="fabD"
                     /locus_tag="ACG8LA_001503"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004314 - [acyl-carrier-protein]
                     S-malonyltransferase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HFQ0203808.1"
                     /translation="MKTAFLFSGQGAQYQGMGKDLYEEAVVKQTFDEASEILGYDMAE
                     LCFTENERLDQTQYTQPAILTVSIAYYRLLKEHGIIPDAALGLSLGEYSALVASNALS
                     FTEAVALVAKRGAYMTEAAPAGSGKMVAVMNAPIETIEESCHEASKYGIVSPANYNTP
                     QQIVIGGEEKAVDEAVLLLKEKGFKRMIPLNVSGPFHTAILEPAAKKLAKDLSQIQFS
                     EPSFPIISNTTTEIMKKETIAGLLEQQVMQPVRFYESIHKLKTIGIEQVIEVGPGKVL
                     SGFMKKIDKTIPVLRVENKQTFDETIAIL"
     gene            complement(21620..21844)
                     /locus_tag="ACG8LA_001504"
     CDS             complement(21620..21844)
                     /locus_tag="ACG8LA_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000035 - acyl binding [Evidence IEA];
                     GO_function: GO:0000036 - acyl carrier activity [Evidence
                     IEA];
                     GO_process: GO:0009245 - lipid A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HFQ0203809.1"
                     /translation="MVFEKIQEIIAEELGKETEEIKLTTDIQEDLEADSLDLFQIINE
                     IEDEFDVKIETEDGIKTVQDLVTYVEKQTA"
     gene            complement(21897..22859)
                     /locus_tag="ACG8LA_001505"
     CDS             complement(21897..22859)
                     /locus_tag="ACG8LA_001505"
                     /EC_number="2.3.1.180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0033818 -
                     beta-ketoacyl-acyl-carrier-protein synthase III activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase III"
                     /protein_id="HFQ0203810.1"
                     /translation="MEQFGMITATASVLPEKIITNNDLSKMMDTSDEWISSRTGIRER
                     RCVTNQETSDLCILVAEKLIKQKNLNPKDLDFILVATMSPDYTTPSVAAQVQGKLGAT
                     HAIAFDISAACSGFVYALSMAEKMIRCGSTKGLVIGGETLSKLIDWSDRTTAVLFGDG
                     AGGILLEANPQKKLLKEKLAADGTRSSSLTAGYQQNKNPFYSEDSEGSYYLQMTGRDI
                     FDFAVRDVANNIQEVMKDKPVDYLLLHQANLRIIEKIARKVKMPQEKFLTNMDKYGNT
                     SAASIPILLDEAVSSGKITLGKQQKVIFTGYGGGLTWGSILMEL"
     gene            complement(22869..23309)
                     /locus_tag="ACG8LA_001506"
     CDS             complement(22869..23309)
                     /locus_tag="ACG8LA_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005471259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HFQ0203811.1"
                     /translation="MEPDLKTVNDYLVSVFNDILTIEESELKKSQFKDLSITEMHTIE
                     AIGMYKKKTTSEVAKELSITVGTLTTAINKLVKKGYVERIRSEDDRRVVKLGLTKKGK
                     LLFRVHQHFHREMVKNILDGMATEEQHALLDALKNLHDFLQDYK"
     gene            23615..24580
                     /locus_tag="ACG8LA_001507"
     CDS             23615..24580
                     /locus_tag="ACG8LA_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HFQ0203812.1"
                     /translation="MLKEKMKTLPMLPGVYLMKDRDGKVIYVGKAKRLKNRVSSYFHQ
                     NKQHSKKVLRMIHHITDFDFVVVDTELDALLLECQLIQHYRPFYNRQMNYFSNYNYVH
                     ITNKGFVLTDTPTARTYGPFRLYKKMPSILRIMEETYQMPWLSEISLLALRVQLPDLQ
                     EMTFEQKKKELQGLFQGRNKKLLTYLKKRQQHFIYQLNFEKAGMLQKDIELVTYFIRR
                     IQEQKQFLRTPSLTFSMPLAADESQKKHYLVCYGQLAETMITSGDVSPDFYYEKKEAH
                     LSLKRQLSKEEIDPVQILISYRKKLEKEQFEIELLNKKEAEKQLN"
     gene            complement(24637..24867)
                     /locus_tag="ACG8LA_001508"
     CDS             complement(24637..24867)
                     /locus_tag="ACG8LA_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HFQ0203813.1"
                     /translation="MTHSQLVAIIKRLEAMVESADNELQVRRFEKEGVEKCTVTYDKA
                     TDTFELTETDTHQQYEFDNIDIVAMEIYDLIQ"
     gene            complement(24953..25840)
                     /locus_tag="ACG8LA_001509"
     CDS             complement(24953..25840)
                     /locus_tag="ACG8LA_001509"
                     /EC_number="1.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HFQ0203814.1"
                     /translation="MKLGFIGTGVMGSAVARHLLEAGHEVAVYNRTKAKADPLVTEGA
                     IWADTPKAVAEQSNILFTMVGYPKDVEEIYYGQSGIFSADISGHILVDLTTSTPSLAE
                     KIAKTAKEKGADALDAPVSGGDLGAKNGTLTIMVGGEEAVYDQVLPLFKEFGTTFTLH
                     GSAGKGQHTKMANQIMIAGTMTGMTEMLVYAQKNGLDLKKVIETLSGGSAANWSLSNY
                     SPRILKEDYTPGFFVKHFIKDLKIALEEAEKMDLVLPATTQALKLYEELADKGFENDG
                     TQALIKLWWPEGKIPEKKS"
     gene            complement(25929..27152)
                     /locus_tag="ACG8LA_001510"
     CDS             complement(25929..27152)
                     /locus_tag="ACG8LA_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010706866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HFQ0203815.1"
                     /translation="MKIGFFTDTYFPQVSGVATSIKTLKQELERHGHEVYIFTTTDPN
                     ADKLEKDVIRMPSVPFISFKDRRVVVRGMWYAYLVAKELELDLIHTHTEFGAGILGKM
                     VAKKLKIPLIHTYHTMYEDYLHYIGKGKVIRQSHVKYLSRLFANHTTGVVCPSERVID
                     TLRSYGVIAPLRVIPTGIDIEKFKRSDITQQDISKLRESLGLQENHLMILSLSRISYE
                     KNIQALINGFPQVISAYPNARLVIVGKGPYVEELEELISELQLEEFVQFTGEVDNNDV
                     ALYYKAADYFVSASTSETQGLTYTEAMAAGTPCVVEGNAYLNRLFDHPSLGKTFETDE
                     DFAPALIDYISSEVPKDPKVLEAKLYDISSTHFGEAMIEFYQDMVVYHEEEMRRKEEE
                     DSIERIKIKLNSFKR"
     gene            complement(27169..28215)
                     /locus_tag="ACG8LA_001511"
     CDS             complement(27169..28215)
                     /locus_tag="ACG8LA_001511"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HFQ0203816.1"
                     /translation="MKVLLYFESEKMLAKSGIGRALDHQKRALTEVGISYTLDEKEDY
                     DILHINTYGINSHNMVNKARREGKKVVYHAHSTEEDFRNSFIRSNQLSPIVKKYLVGL
                     YQKADYLITPTPYSKQLLESYGIRVPIQAISNGIDLEKYHPDPMKEQKFREYFKLSPD
                     QKVIICVGLFFERKGIIDFVEIAKKMPEYTFIWFGHVPMYSIPRNIRKIVKEDHPENV
                     LFPGYIRGEIIEGAYSGADLFFFPSYEETEGIVVLEALASKQNVLVRDIPVYNGWLED
                     SKNCYMGKTNEEFIRLIQQITNQELPSTTQAGYQTAKERSINKIGEELKNVYESVLNE
                     KVSSKLKKVNQVKD"
     gene            complement(28379..30106)
                     /gene="ptsP"
                     /locus_tag="ACG8LA_001512"
     CDS             complement(28379..30106)
                     /gene="ptsP"
                     /locus_tag="ACG8LA_001512"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008965 - phosphoenolpyruvate-protein
                     phosphotransferase activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HFQ0203817.1"
                     /translation="MVEMLKGIAASDGVAVAKAYLLVQPDLTFSKATVEDTAAEEARL
                     DAALAKSTEELQQIREKAAQSLGEAEAQVFDAHLMVLSDPEMVGQIKQNIKDNSVNAE
                     SALKEVTDMYIGMFEAMEDNAYMQERAADIRDVAKRILAHLLGVTLPNPSMINEEVVV
                     VAHDLTPSDTAQLDRNFVKAFVTDIGGRTSHSAIMARSLEIPAIVGTKEITAKVKEGD
                     ILAVNGIEGDVIIDPTDEQKAEFEKAGADYAAQKAEWEKLKNAETVTADGKHFELAAN
                     IGTPKDLVGVHNNGGEAVGLYRTEFLYMDSPDFPTEDDQYEAYKAVLEGMEGKPVVVR
                     TMDIGGDKELPYLQLPHEMNPFLGYRALRISLSEQGDEMFRTQMRALLRASVHGNLRI
                     MFPMVATLKEFRAAKAIFEEEKQKLISEGKEVSDTIQVGIMIEIPAAAVLADKFAKEV
                     DFFSVGTNDLIQYTMAADRMNERVSYLYQPYNPSILRLIKNVIDAAHAEGKWAGMCGE
                     MAGDQTAVPLLVGMGLDEFSMSATSILKTRSLMKRLDTAKMAELADRALKECDMMEEV
                     VELVHEYVK"
     gene            complement(30106..30372)
                     /locus_tag="ACG8LA_001513"
     CDS             complement(30106..30372)
                     /locus_tag="ACG8LA_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010773230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HFQ0203818.1"
                     /translation="MEKKEFHVVAETGIHARPATLLVQTASKFNSDVNLEYKGKSVNL
                     KSIMGVMSLGVGQGSDVTITAEGADEADAMAAIVETMKKEGLSE"
     gene            30851..33085
                     /locus_tag="ACG8LA_001514"
     CDS             30851..33085
                     /locus_tag="ACG8LA_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFQ0203819.1"
                     /translation="MLCQNCGKNEATIHLYATVNGQRTQLDYCQSCYQKIKNQQNGGL
                     TNMAQNDPFGFGSLDDLFRSMSRQMQQQGNYEQTPPTQFGGNNNFNGGQPPQGNTEGL
                     LGEYGINITEQARQGDIDPVIGRDDEIKRVIEILNRRTKNNPVLIGEPGVGKTAVVEG
                     LAQKIVDGDVPQKLMDKEVIRLDVVSLVQGTGIRGQFEERMQKLIEEIRQAENVILFI
                     DEVHEIVGAGSAGDGNMDAGNILKPALARGELQMVGATTLNEYRIIEKDAALERRMQP
                     VRVDEPTVEETISILKGLQKRYEDYHHVKYTDEAIEAAATLSNRYVQDRFLPDKAIDL
                     LDETGSKKNLTIQIVDPKTIEKKLQEAEEQKVLASREEDFEKAAYYRDQINKLQKMKE
                     RQLTEEETPVITEKDMEKIVEQRTGIPVGELKEKEQTQLKNLADDLKAHVIGQDNAVD
                     RVAKAIRRNRVGLNKQNRPIGSFLFVGPTGVGKTELAKQLAYELFGSQDSMIRFDMSE
                     YMEKHSVSKLIGSPPGYVGYEEAGQLTEKVRRNPYSLVLLDEVEKAHPDVLHMFLQIL
                     DDGRLTDAQGRTVSFKDTIIIMTSNAGTGKVEANVGFGAAREGVTRSVLNQLNNYFTP
                     EFLNRFDGIIEFSALSKENLMTIVTLMLDDVNQMLAAQQLHIEVPTNVKEKLVDLGYD
                     PSMGARPLRRTIQEQIEDGIAEFYLDHPSIHELKAKLDKDGKIIVTSKPERLAKESAE
                     ETAE"
     gene            33233..33553
                     /locus_tag="ACG8LA_001515"
     CDS             33233..33553
                     /locus_tag="ACG8LA_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HFQ0203820.1"
                     /translation="MKLVNVTNSHSRLVLNQLENTDAHLVKVYTAGNTTIVYTEAPEH
                     NEILLINDKRKIQPKEIEDAKNYFLDKIKDAVYHEDEIKVIELAGLVEISIPKHELGA
                     TLAV"
     gene            complement(33758..33982)
                     /locus_tag="ACG8LA_001516"
     CDS             complement(33758..33982)
                     /locus_tag="ACG8LA_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein"
                     /protein_id="HFQ0203821.1"
                     /translation="METEWQRRERKKQKKEEMLRLCRLLDVKDWDKNEQIAQKVRSII
                     HKEEKVKNKDTRRTENEKRKVQKKREKSKS"
BASE COUNT         9599 a         7375 c         5939 g        11179 t
ORIGIN      
        1 cttatcccat caatcccaca gattctattg agcatctgtg tctttgagga atacctgtta
       61 tctattgttc ggattgcttt ctatctacta cttttttaca ggaaatttac ctattagttt
      121 tctctgctgt aatttttgac ttctgcttcc atagcatcaa taaagatatt caaatcttct
      181 acagctgttt ctttacttcc ataacgacgt acgttcactg ttgcatcttc caattccttg
      241 tctccaacaa ctaattggta agggatcttt tgtgtttgag aggcacgtat cttatagccc
      301 attttttcat tacgatcatc aacttctaca cgcaacccct tcatttgcaa acgttctttg
      361 atttcataag cataatcgcc atgtgcatca acagaaacag ggatgattgt tgcttgtata
      421 ggtgccaacc atgttggaaa agcgcctttg tatacttctg ttaaataagc gacaaaacgt
      481 tccattgtag aaacaattcc gcggtggata actactggac gatgcgtatt ttccccgtct
      541 tctccaacat atgtcaaatc aaagcgctct ggcaataaga agtctaattg tatagttgat
      601 aatgtttctt ctgtaccaag agctgttttg acttgaacat ctagttttgg tccgtaaaag
      661 gctgcctcgc cttctgcttc aaagtaatct agttctaatt catccatagc ggctttcagc
      721 attgcttggg ctttttccca cattgcgtca tcatcaaaat atttatctgt attgtttgga
      781 tcgcgatagc tcaagcggaa acgataatct gtaatattga agtcagcata tactgccacc
      841 atcaattcaa gcgtacgttt aaattcatct ttgatttgat caggacgaac aaatgtatga
      901 ccatcattca acgtcatttc tcgtacacgt tgtaaacctg acaaagcacc tgatttttca
      961 tagcgatgca tcattcctaa ttcagcgata cgaattggta attcacgata agaatggatc
     1021 gtgtttttgt agaccatcat gtgatgaggg cagttcattg ggcgaagaac aagcatttcg
     1081 ccatctccca tatccattgg cgggaacatg tcttcttgat aatgatccca gtgtccagat
     1141 gttttgtaca actcaacatc tcccattatt ggtgtatata catgttggta acctagacta
     1201 acttctttgt ctacgatata acgttcgatc gtgcgtcgga ttgttgcccc ttttggaagc
     1261 cagaatggca aaccagaacc tacttctggg gaaaccatga acaagtcaag ttcttttcct
     1321 agtttacgat ggtctctttc ttttgcttct tcacggagac ggatatattc tttcaaagct
     1381 ttcttgtcaa aaaaggctgt cccgtataca cgttgcatca tttgattgtt tgagtttcca
     1441 cgccaataag cacctgccac tgataataat ttaaatactt gtatacggcc agtggatgga
     1501 acatgtggtc cacgacacaa atcgatgaat tcgccttgtt gataagcagt aatcacttct
     1561 tcttctggca attcactaat cagttctact ttgtacggat cacttgcaaa aatttctaat
     1621 gcttcctgtt ttgaaagaac acggcgttcg atcggcagat tttctttgac gattttcatc
     1681 atttctgctt cgattgccgg caaatcttct gcagttactt ggttttgtcc attatctgta
     1741 tcgtagtaaa accctgaatc gatagctggt ccaacgccaa agtggatatt tggatagagg
     1801 cgacgcatgg cttgggccat caaatgagct gctgaatgac ggactaagcc aagtgcatct
     1861 tcatggtctg gtgtgatgat ctcaatactt gcatcttcct cgattggacg agtcaaatca
     1921 acgagttttc cgttcacttt accagctaaa gctttttttg ctaagctttt tgaaatgctt
     1981 tcagcaattg ccaatgttgt tgttccagac tcaaattctt tgactgcacc atctggaaaa
     2041 gtaattttta tcataatagt ttcctccttg aaatgttttg attgatcaga tcatcaagct
     2101 gaaaaacaaa aaaatcctag catctcttga aaagagatac taggacgaaa agttcgtggt
     2161 tccacctaat gttcaaacgc aaatgcgttc ctcaagcgtt gtaacggtcc gaccgccctt
     2221 gcttcaacaa gggtttcgaa agtggtcatc ctttggtttt ctcctggaaa agtttcagcc
     2281 tagcttttcc tctcttatcg aagactctca aattcagttg gctttctcat caatcaatta
     2341 tgtgtttatt taaccactaa taaatagaaa aatcaagtgg gaaactaaac ttattttttc
     2401 cattccccat ttacaccgta tgttcctttt ttcatctcat tgatgatgac atggatgtgt
     2461 tcttttggtg cctgcgtgtt tttatgaaca gcttccgtga tatctttcat catattttct
     2521 aattgttccg gactgcgacc ttctactaat tcgacatgta cgaatggcat aatgctctct
     2581 cctctttctg atcgttcttt tttcaactcg attctatcat actatgtttg tcttgggtac
     2641 tgaatcagga aaaatggctg gatctttttt tgctctcaag gcactcaaaa tagagaccgt
     2701 atccacgact tcttgcaaaa cagctccgaa taatgcgggg attagtcccg tacttgcaat
     2761 taacatcaaa aaaatacaaa taaagatgcc aatcagtaca gactgtttcg ctattctcat
     2821 cgtatctctt gaaatcacta ctgcttttgc tacacgcaag agatcatctt tcaagatgac
     2881 cgcatctgca ctttcactag cagctgtaga accatgagcc cccattgcaa taccgatatc
     2941 tgcagcagca agtgctggtg cgtcattcac gccgtctcct accatcgcaa caggtctttg
     3001 atctttaggg atactttcta aaatggtcag tttatcttga ggcaagctac gggcatgtac
     3061 agaatctaat tggacttttt ctgcaatcgt ttgagcaatg gcagatccat ccccggtgat
     3121 catcatcaaa tttttcacat caagttttct tagctccttg attgtctttg ctgcttctgg
     3181 gcgaatctga tccgaaaata ggatcgttcc tgcaaaagat cgatcaattg ttacatagat
     3241 tgctgtattg gacgtttcta tttcttcagc tgaaacaaaa gaggcacgtc caatctttac
     3301 ttcatgatta ttgactactg cttggattcc ttgaccggtc acttctttca gttgactaac
     3361 aggatacagt tggctgtttt tcacgttgtt cactaacgaa cgagctaaga tatggctaga
     3421 ttcctgttct gcactagctg catacagaag tagctcttct ttttttattc cattgactgg
     3481 ctgaatcgcc tctacttcca atatcccttt ggtaagcgtt cctgttttat caaaagcaat
     3541 cgtttttgta cgtgcgagct tttcaatcgt tgttccagtt tttacaacga tcccgttttt
     3601 acttgaacgg ctcattcctg caactaaagc aatgggcgca gctagaatca gtggacaagg
     3661 tgatgccact accagtacct cagcaaatcg taaagggtct tttgagaacc accaagaaat
     3721 accaccgatc aaataagcaa tcaacgtgaa agggactgca taacgatcag ctaaacggac
     3781 aaatcgggca ggcttttctt ttgattcttc gactagttta ataatcattt gatactggct
     3841 gtctgcggca cgtttttcag cgatcatttg gatcgatccg tctccattta aagaccctga
     3901 cataatctga tctccaggtt tcttggtttc cgggcgggac tcacctgtca aagaagattc
     3961 atcgaccgaa gattctcctt tggtcactcg accatctgcg ggtacaagtt cgccaggctt
     4021 gactagtaac tggtcatcaa tatttatttc atcgattact atatcctgca attttccttc
     4081 tttgaatcga tgggcaattc ttggggtgtt atctaacaaa gactgcagtt ctttacccgc
     4141 tcgtttattc gcgtaatcct ctagactatc tccgcccgta agcatgatca atatcatcaa
     4201 actagcccag tattctttga cggctaatgt tgcaaggatt gcggtaatcg ctaatacatc
     4261 tacgccatat cttcctgaac gtaacgtctt gatcatttcc aaaaacatca agaaggcgag
     4321 aatccctcca gtaaatgcga caatcgcaaa tgcaagggcc ggctggtgaa aaacaaattc
     4381 acttaataaa gctatcccac caataagcaa agtaagtaaa aattttttga aatgtgtcat
     4441 tgttttttct cctcttttat gtgacttaga gaggttagta ataaatttcc agctgcctct
     4501 ttcatcttaa gcatagtcct tgactagcac tttttaaaac aataggcctt aattgaaaac
     4561 aactatcact atcagcgttt ccaaaattca tcagttctac aaacaaaaat attcagcaag
     4621 gattactttt tcgattcatc agttaaaaag tacctttttt cgaaaaacta tgctatactt
     4681 ttaattcgtt atttacggcg gaaggagcaa acatgcgatg aatgagaaac aactagaaca
     4741 aacgcacgtg gatgaaacga tcgaactaat ccagatcgaa caaaatatgc tggatacaaa
     4801 acaacaagaa ttgactcagg aaatgaatca ttcgacaaaa gacacagcta atcacaagat
     4861 tcgagctggt tccaatgaag ctttttatga atctgctgtt gaatatcgcc aacatgagca
     4921 ggaattgctt ttgaaatacc atactcttga agcacagcaa aaacgcctgc aaacgttgtc
     4981 tgtcatgaaa gatagtcctt attttgcccg tatcgacttt aaagaagacc gtgaaacaga
     5041 aacattatat ctaggtatcg cttctttaag agatctggca gaagaaacaa tcgttattga
     5101 ctggcgcgca ccaattgcca atctttatta tgaaggtgag attggtcccg cattttatga
     5161 aactgaaaca gatagaatag atgtcgatct gcagttgaaa cgacaattta aaatccaaga
     5221 aggacgtatt ttatctatgg tagatacgtc ggaagtaatc aatgatgact ttttgctaga
     5281 gatattggat gaatcatcaa gcaaccatat gaaaaacatc gtctctacga tacaaaaagc
     5341 acaaaatgca atcattcggg acacaacaag taaagtaatg ctgattgaag gaatcgccgg
     5401 aagtggaaag acatccgctt tgcttcaacg tattgctttt ctgttgtatc ataatcgcaa
     5461 gtggctcgag gctgaaaacg ttcttctatt ttcacccaac catttgtttt ctgattacat
     5521 ctcgactgta ttgccttcat taggtgaaag cggcgtgcct acacagacat tcaaaaatta
     5581 tttggtgcag ctgctgccag agttttcttt actagatgaa cagcaacaag aaagtggttt
     5641 tttgctaggg gaaaaagatc cgatacaagt gatgaaaagc ggattgacct tagtcgatca
     5701 gattgatcgc tatatccaag gcatcacaaa ctacggtccc ttgttccgtg atatgaaaat
     5761 aaatggccgt acgatcctat caaaggaatc gattcgccaa tggtataaag aaacaaatga
     5821 acaattacct ttacatcata gactttctct attacaaacg aagctcctga aaaaattagg
     5881 cggtctgcaa aaagacgaaa cacgtcagca atgggtcaaa gatctggcgg aagaacagct
     5941 ccaagaacta tacgcaacag atccaaatct tgaatataca gaacaaaagg agcgttcatt
     6001 acgtaaaaaa ctggccaacc aaatcgtacg taaaagattc cgtcgaatcc atcgagggat
     6061 catgaattat caatttgtca atataacgaa acaatatctc cactttctac aaactgtgcc
     6121 actttctctt ctaacacgac ataaaatcag cgagaccagg tggcaggaac atttgacaac
     6181 tgttcgtaca cacttgcgtc aaagagaatt gcgtcaagag gatgctgtac tattcttttt
     6241 actgatgcgc cgaacatatc cagtgacggt tacacacaaa gctcgctata tctttattga
     6301 tgaaatgcag gatttcgcac catcacaagt ggcattgctg caagccttgt tcccaaaagc
     6361 aaatttgact ttctgtggag atctaaatca aaatgtcttt ggaaatgaaa cgatcgttgg
     6421 atcattggaa gaccttttcg tggaccgtga agtcactcgt ttccaattaa cgacaagcta
     6481 tcgctccaca aaagaaatca ctgattttgc taatcatttt attgtgaaag aacatcaagt
     6541 agaaacaaca gcaagaaaag gagaccttcc tttgctcatc caaggaacaa cagatgatat
     6601 caaattgaat tggttagcag ataccattcg aacgactcag ggaaaagccc ggtattggcg
     6661 tacagcaatc atagctaaaa cacaagaaga atgcgaagct ctttatgctc aactgccaga
     6721 cgagttgaaa caacaagtcc agctgatttt aaatgagagt gactttatga agcgttccat
     6781 tattttactt ccagcctttt tagcaaaagg tctggagttt gaccgagttt tcttgtggga
     6841 tgtagatgca gaacattttt cttctcagca agacaaattg atcctttaca ccatgtgtac
     6901 acgtgcgatg catgaattga ccctttttac ctccaataat gaaagtcctt tgttaaacaa
     6961 tatggatatt tcatcttatg agaaaaaagt actgtaagta aaaagacaac tgctatcatt
     7021 aatgttagca gttgtctttt tatttacaat aataattgca gaaaaagtaa ttcaatcatt
     7081 taaggtcatt tattctatat ataaatccaa atctgtttca ggatatttta atttgacaag
     7141 cgaaataatc attttcagtt cttccatgtt ttctggatat tctgggtcaa ataccttgct
     7201 atgacggcca atcccgccat tgtcgatcaa tcggtaaatt cgattccatt caatgaattg
     7261 gtcaattgat tggaaattgc tgattggata gccgccacaa tccaaaatct ctgatacacg
     7321 aaatgctagg tatgcactat cgatcacttt attttttttc gtgtctatct tctcatttct
     7381 ttcgataaga attttttcag gacgatgttt caagctccac tctaatagta gaaagaaagc
     7441 ctccatccga tactcttctt caaataaccg aaaggctgaa tcagaacgac gaaaaagcag
     7501 cggaatcaga taattttgtc tataaatcag cattggtgcg cggtccacca tacactctaa
     7561 ataacggttc agataccctg taccgacata gtttcctaat cgatagcctt caacgccgaa
     7621 tcttgcgtat ttttgcgcta attttgaaca atcagttacg ttcacagcta actcttctac
     7681 tttgcggtaa ccgcttaaga tacgttcaaa aggttctaaa gtgatttttg cttccatatt
     7741 cttccccgtc catcttccac atacttcata tcatttcaca tgatacttat gctctcatca
     7801 taccacaggt tgaattagaa aagaaaataa atcacacaaa aaagcaagac aatctgttag
     7861 tgagattgtc ttgcttttcg aaaaagactg aatacttttc gttaaaactg gttgcttagt
     7921 cttctaatgc cacattatgg aacacatgct gtacatcttc tagatcttcc agtgcatcaa
     7981 tcattttttc aaatgtttct tgatcttctg gagatagtgt tacctcgttt tgagggatca
     8041 tttggatctc agcgattgaa aaatcagtga ttcctttttc ttttaatgct tcttgtatac
     8101 tatggaaatc cgctacttca ccgtaaacga tgatttgtcc ttcttcttcc attacatcgc
     8161 gaacatcgat gtctttttcc attaggtatt caaggatctc gtcagcgtct tctcctgcaa
     8221 aagcaaagat tgctgtattg tcaaacatgt aagaaaccgc tccggaaaca cccatgttcc
     8281 cgccattttt cccaaatgct gcccgtacgt ctgctgctgt tcgattcaca ttgttcgtca
     8341 atgtatcaac aatcaccatt gagccgcttg gtccaaatcc ttcatagcgc aattcagagt
     8401 atgtttcatc tcctgcacct tttgcttttt cgattgctcg gtcaataata tgttttggta
     8461 cattataagt tttagcgcga tcaatgacga aacgtagttt ttggtttgca tgcggatcag
     8521 gatcacctga ttttgctgcc gcgtagattt caatcccaaa ttttgcataa atccggctat
     8581 tattagcatc tttagcagtt ttctttgcta cgatatttgc ccatttacgt cccatatttt
     8641 cacttcgctt tctgatttga tagtttcata acgcaaaaac gtcctgttcc attatacttg
     8701 tgaatcacga ttctgtgaag ctttttttct ttcttccttc attcttctca tttttagtca
     8761 attatctata ctcggattgg gatttgcccg aaattctgtt ccggaatatt gcctcccaat
     8821 tgatagattt gatcacttct aactaacagt tccgcttctt gtgcctcttt ttttccgatt
     8881 cgggaataaa tagaaatctc ttttttttct tttaagaatc ttcttccagc atcggtaaat
     8941 ccaagtagtc gaagataatt tttattttgt tggacaggaa tctcttgctt tttgatattc
     9001 agcaagacat aacaagataa tcgttggatc cgtgtccatg tatatctttt tgtttttacc
     9061 tttgacacaa aatcctcaaa actatcagca gttgcagctg ctgttttcat gcgcgattct
     9121 attccttcgg tcatctgata gatatctgtc agttccagca aagtagaaga taacaaccga
     9181 taacgcaaat acggccaata agattcccaa gtctgcagcg aacaagttga aagatcttct
     9241 tctgtctgag gcggcacaag tccagctatt ctttttcctt cttctaacgc atggcgaatg
     9301 gctgttgcac tggctatcct ctgatctgtg atgatttttt catgatagcc tgcactttta
     9361 cgtcggatcg gatgtaattc catagggtgg acatacttgg cattttcctt tgcataactt
     9421 aatcccaaga tatgatttgg cgaagaaaaa tcaagcgtaa tatcgggata cagactgcga
     9481 aaaacctcag tcattttttg cggataacta tacgtttgat cagacagttc ttgaaatgcc
     9541 tcttctatcc tatcttgatt ctcttggaca aagcgtccga aactgctgta atcaaacgaa
     9601 gtctcttctt ctgttccaaa acacaaactg tcacagtcca gtgtttgcaa gatttttact
     9661 gcacctttag caaaatagtc agctgactga accgcccatt cgacgggaag ctccactact
     9721 aaatccacac cattttgtaa agcttcattc gcgcgatgcc atttatcgat gatagccggt
     9781 tcgcctcttt gcaaaaaatt cccgctcatt acagcaatga cgacctctgc tcctgttatt
     9841 tttcgtgcca tttccacatg atagcgatgt ccattgtgaa aaggattgta ctctacgata
     9901 atcccgcagc ttttcatgcg catcctcctt catagttatc gataaaaaag aaatagagac
     9961 aagtaaaaaa aggcaaaaat cggaaaaaat acccgaacta tataaactat tctcgcaaac
    10021 acaatacttc tgcgacgaaa agctgcactg caagagcaat gcctatatcg ttcggatata
    10081 taatttatgt tgaagattta ttcttttctt gttaactcga gcaggcaaaa ccgctagtct
    10141 ttgtatgcta caaagaacca gcgctttgat ttctctgatg ctgcttcgtc tgtaaaatca
    10201 gaaaatgctt cgactttcga aaagccgctg ttttccagca ttcttaaata actttccaat
    10261 ggataggtac gctcttgatg tagttcatct tcacgaataa atcgaccaga cccttcttgt
    10321 tcttcaacga aaaaggtaag aaaatgttcg atgctgtgtt tctcgcttcc tggataacta
    10381 tcccacaaaa aagcaaaatt atccccttga taatgatagc tatattctgg aaaaacctca
    10441 tctacttgat aggtggagtg tacgtcaaat aaaaatcggc cattttcttc taacgcttga
    10501 tagacttcat caaacacttg ctgtacctct tgtctatttt tcatatagca cagcgaatca
    10561 gaaaaacagg taattgcctg atattgtccg atttctgata aatcgagcat attgccttcc
    10621 acaaattgga tcgatgcgtc ttcttcatat gctcgctggc tggcaatcat caacatctct
    10681 tctgaaaggt ctaaccctgt cactttatat ccatcttttg caaaggcaac cgctaatgct
    10741 ccagtaccgc atgccagttc caaaatattt tttgtgtctt cttgtaaatg acgtttcgaa
    10801 aaagctaacc attgctgata aagtgtttcg tccatcactt catcgtaaat gaaagcaaat
    10861 gtttcataag ccatatgtta atccaaccat tcactaagat cgactagcgg agcatctgac
    10921 catagttttt ccagattata gaaatttcgt tctggcgcat ggaaaacatg tacgatcaca
    10981 tctccaagat cgatcaatac ccattttccg ccttcttttc cttcaatacg ttttacttca
    11041 tatttgtttt cttcttcttt atcaatgatt tcttctgtaa ttgcgttgat ttgacgttcg
    11101 ctatttgctg aacagatcat gaaataatct gccaacaagg aaacatttcg aacgtctaaa
    11161 gcgataatgt cttctgcccg ttttgaatct gctgcttcaa tcgcaatttt taattgttct
    11221 ttactatcta tgatgatttc ctcctaatat gagcagctta tttttttgct acccagtaat
    11281 tatatgtttc gattgttttt ggataaatct gttgttcttg cgcaagcaaa tgggccaatg
    11341 tatgttttgt ttcaaatgct acagcttcgt ctagatcagc ccatgcaatg gctcgtgcat
    11401 cttgtacccc aggaaaatct cgacctggtt caatatagtc tgctacataa atgattttgt
    11461 caaggagact catcttagca gccccagtcg tatgcacccg gattgcatga agaatctctg
    11521 catcggtgat tcctaattcc cgctctacaa acgaagcgcc aacaagacca tgccagattg
    11581 cattattata attcaataac tccggatcaa aaccgtctct tacgattacc attttgaact
    11641 cctcatctgg tcgttctttt gcataatcat gtgtcaatgc agcaatacta gctttttcag
    11701 gagaagcacc gtattttttg gcaagagcca cggctgtttc ttctactcca agcacatgct
    11761 tgaagcgttg ttcgctcatt ctcatctgta ttttttgcat caggttttct ctagaataag
    11821 cagtatattc attactatag tccatattca tacaaccctt cattttgaat ataatcaatt
    11881 actttatctg gaacaaggta gcggatagaa cagccttctt tgatcttttg acgtattttc
    11941 gtggaactga tgtcgatctc aggtacatct acccaaatta caggatatgg agtatccgtt
    12001 gtgtatcctg gtcgacgtat acccacaaag ttgaccatag aagtcagctc atcgatttta
    12061 taccattttg gcaaatattc taccatatcc ccaccgataa taaagtaata atctgtatcc
    12121 ggattgtttt gcgtcaattc cttcatagta tcataggtgt aacttttccc accacgagct
    12181 aattcaatcg tttcaatctg caaaaaagga ttgtcttcca ccgctaattc caacatgttg
    12241 agtcgatgtt ttgcatcaat cgtctgtttc tcatcaacat gaggtggctg ataagaaggc
    12301 atcaaaaata cgcggtcaag acctaaattc cggccagctt gttcagccat cactaaatgt
    12361 gcaaggtgaa cgggattgaa tgttccgccc aagatcccta cttgcttttt cttctctaag
    12421 aattgaggca tttcttcagg aaataattgt gaacgaacaa atgtcttagc ttgcgtattc
    12481 atcatggtca ctccttatat tgcttttact tcttttgata gcctttgata cttttctttt
    12541 gtggaaggtt tgtataatac aataacacgt ccaatgattt ggacgatttc gcaatctatt
    12601 tctttttcta atacttgagc tgcttcttct gcaatctcat ctgtattttg aagtaacgat
    12661 actttgatca gttctctttt ttctaaagct tcttcaattt gaacgatcat tgctgaattg
    12721 atcccacctt ttccgatttg aaaaatcggc tgaagatgat gcgctttgct acgtaaaaaa
    12781 cgcttttgtt ttcctcttaa actcataatt ttccttcttc cttaaatcaa tgctttgcgt
    12841 ttcaatacat ctacaccctt tggcgcccag cccgcaatta ctactggcgc tgttacagtg
    12901 atccagccta gaccggcaaa aacgatgtct gttttttctt tcacagaaaa ctcaaaacga
    12961 acaagctccg gaaatgcctc gacttcatca ggacgaggag gctgtaataa tccacctaca
    13021 tgtttttgat aaaattcgtc tgctttttcc agtttcgttc gatgaatatt tacatcattt
    13081 gacacataag caataaatga agcacgattg ccgctgataa aatcaaatct tgcaagtccg
    13141 cccaagaaaa gtgtttgccc ttcattcagc tgataaactt taggtttgat ttcttttaac
    13201 ggtgcaatga tccgcaaatc ttttttacct aagtagtgcg ccatttgatg gcgatggata
    13261 attcccggtg tatcaatcaa aaaatgcccg tcatctaaag gaatctcgat tttatccaag
    13321 gtcgttcctg gaaactgcga agttgtgatt acatcttgta ctcccgctgt atttttgatg
    13381 atttgattga taagcgtcga ttttccgaca tttgttactc cgacgatata gacatcccgt
    13441 ccatcgcggt attcttcgat tttttctaat agttccgtca tctcatgaga tttcttagca
    13501 ctagttaata atacatctac tggacgaatt cctgcttcgt aagcacgttc cttcatccat
    13561 tgtgttaatt tagttttttt caatgattta ggtaatatat ccactttgtt cccaactaaa
    13621 agtactggat tgtcaccgac aaaacggtgt agtcctggga ttagtgaacc attgaagtca
    13681 aaaatatcca ccacattgac gatcaatgca tctttttgcc ctaattcatt cagtaagcgc
    13741 aaaaagtcgt catccgtcaa tgagacatct tgggtctcat tataatggcg taatctgaaa
    13801 caacgctgac aatagacttc cccggaagct aaaccttttt ccaaagccgt ttgcggcgtg
    13861 tatcctaatt caccgggttt gtttgtttgt ataacggcac cacagccgat acattgtaat
    13921 tcttctgtca ttcgattcca cctcgccagc ccatatcagg gtgttttgct aatagatagg
    13981 ccataattct tttttcccaa aaacgattaa attgtgtctt ccaactatct gttgcgataa
    14041 tgggttttac aaggatgcta cgtatccctg cacgattggc tccacgtata tcagtcataa
    14101 tctgatcgcc taccattact atctcatcat ctgctaaatc caattgtttc tttgctatgt
    14161 tgatccctct tgctaaaggt ttcattgctc gtgcaacata caaaagatca aatttttcaa
    14221 tcgctcgcgc gacacgtttt gaattattgt ttgaaacaac aacaacaggg attcctgcat
    14281 ttttcatttc taaaatccaa gtaagcaact cttctgttcc atctggatta ttccatgcaa
    14341 tcaacgtatt gtctaaatcg gtcaatactg ctttgatgcc tagattcttt aattgggcag
    14401 gtgtaatctg atagatggct tctaccatcc atgttggttt gtaatttgaa aacatgctgt
    14461 ctcctcatct gcaaaaaatg aaggagcaca taaagtactc ctcaaccccg tattatactg
    14521 catatcagca aaaaaaacta cctctatact cgttcgtctt tcagaaaaag catttcttta
    14581 caaaatgacc aaaaataaag attgatcaca gaaaaattta gaaacaaaaa acaactaata
    14641 ttggcggaac ctcttgtatc gtttttccag taatttatgc tgatctaatc gaacaagttc
    14701 cgtcaatctt tcaatcaacg cttttttcat aatgtgtgcg actttatatc gtggcaactg
    14761 ctcgccgttg aacgtttcag gaataactcg atcaacgatt cctaactcgc gtagttctgg
    14821 cgcagtaatt ttcatcaact cagctgcttc tgcggcgcga ctaccgtctt tccacaaaat
    14881 cgacgcaaat ccttctggag aaagcacagc ataaatcgtt tcttccagca tccagacttc
    14941 atccgctaaa cctagagcaa gggcaccgcc acttccacct tcaccaatga tgatggcgat
    15001 gatcggtacc tttaaatcag acatttcgag cagatttctg gcaatagcct ctccttcgcc
    15061 gcgctcttct gctcctacac cgcaatatgc acctgctgta ttgatcaagg taatcaccgg
    15121 tctattgaac ttttccgctt gtttcatcag tcgtaaagct tttcgatagc cttcaggatg
    15181 gggagaacca aaatttctgc ggatattttc ctgcagatcc cgtccttttt gaataccgat
    15241 cactgttacc ggtttgccat ctaatcgagc gattccacca acaatcgctt cgtcatctgc
    15301 aaataaacga tcaccatggc attcctcgaa agaatcgaag atctcttcaa aaaaatccaa
    15361 gcttgtccat cgttctttag ctcttgctaa ctgaacgaca tcatgtgctg tcttatccac
    15421 gatctatcca tcctttctgt gtatgcaatt caagaagcgt atggattttc tgtttcaatt
    15481 ccatgcgggg aacaatctga tcgacaaaac catgagataa taagaattca gccttttgga
    15541 aatcttctgg aagttcctgc ttgatcgtct gttcgatgac gcgtcttcca gcaaaaccga
    15601 tcaagctttg gggttctgct agaataatat cgccttccat tgcaaaactg gcagttactc
    15661 ctccggtcgt cgggtccgtt aaaacagtta gataaaaaag accttcattg ctatgccgtt
    15721 tgacagcagc agagattttt gccatctgca ttagagaaaa gattccttct tgcatccgtg
    15781 cgccacctga agctgtgaac aagacgactg gaagactttc ctttgttgct cgttcgaata
    15841 atctggtgat cttttctccg acaatcgttc ccatacttcc catgataaaa ttaggatcca
    15901 tcactccaat aatgaaggga atcccctgaa tggttgcttt accagtgagg actgcttcat
    15961 gaagtcctgt tttatcttgc atttttttaa ttttttccgt atattcggga aatgctagcg
    16021 gatctttggt tacaagatcc gtatcccatt cttcaaaact tttttcatca ataatcaaag
    16081 ctagacgctg ccatgcaccg attcgaaaag cgtatccgca atgagggcat actttttctt
    16141 caccgatgtc tttcgtataa aggatatgtt tgcaatttgg acactttgcc cacatgttat
    16201 caggaacaga tggcgagtta gcaggtttgc tctctctatt aggattgatc cgaatatatt
    16261 tctttttctt aaacagagcc atctatgcgc ctcctatctc cgtttctggt gtccaattcg
    16321 gtaaaaattc ttcttgtaaa aatgctgtgc tgtaatcacc tgctatgact gcaggatgac
    16381 taatcaaatc catctgaaat tctgcgttcg tgatgattcc ttctgtgata aattcactta
    16441 aggctcgctg catcttcatt aatgcttcaa aacgcgtatt tccatggacg attatttttg
    16501 caatcattga atcataatat ggcgggatcg tatatcccgg gtaaactgca ctgtctactc
    16561 gcagtcccat cccacctgct ggaagcagta agttttggat cttccctgga gaaggagcaa
    16621 aatggaaagc aggattttct gcattaatcc ggcattcgat tgcgtgtcct tggaatacta
    16681 cttcttcttg acacacattc aaaggctcac cggctgctat ctccacctgt ttttttacta
    16741 aatcgattcc tgtgaccatt tctgttactg gatgttccac ttggattcga gtattcattt
    16801 ccatgaaata aaaatcgcct tcttcatcca tcagaaactc gatcgttccg gcattttcat
    16861 aattgactgc tttagctgct cgaacagcag cgtctcctag tgcttctctt tttgtttgtg
    16921 agatcactac agaaggagat tcttccagta ctttttgatt gttgcgttgt aaagaacaat
    16981 ctcgctcgcc taaatgaatg acatgaccaa atcgatcacc taagatctga acttctatat
    17041 ggcgagcagg ataaatgatt ttttccaaat acatatcatc atttccaaat gccgctgctg
    17101 cttcttgctg agctgaagaa aaatgctgtg ggagctcttc ttttgattga actttccgaa
    17161 tgcctttccc gccaccacct gcagctgctt tcagcatcac tggataacca attctgtctg
    17221 ctatttccaa tgcttcttct actgtagata atacaccagt acttcctgga atgactggga
    17281 catttgcttc ttgcatcaat tgacgcgcat tgatcttatt tcccattgca tcgatcgttg
    17341 cacttttagg accaataaat gtgatattgc actcttcaca catggaggca aatcggctat
    17401 tttcagataa aaaaccaaat cctggatgaa ttgcttcggc ttttgtcacg attgcagcgc
    17461 tcagtacttc ctgaacattc agatatgaat caacggcttt tgccgggcca atgcagattg
    17521 cttcatctgc taactgtgta tgaagtgctt cggcatctgc ttctgaatat atcgctacgg
    17581 tttggatccc tagttcgcgg catgcacgaa tgatacgtac agcgatttca ccgcggttag
    17641 ctatcaatac tttagaaaac atatttcacc tatccaatca taaaggttaa ttccgcttcg
    17701 gctacttttt taccgtctac tttagcgatt cctttgccta ttccggctga agctttcact
    17761 ttcaatatct caacttcaag gtataaggta tctcccggtg taactttctt acggaatttt
    17821 gctttgtcca atccgccgaa ataagccgtc tttcccttga attgttcaag agaaagtaat
    17881 gcaactgctc ctgcttgagc cattgcttca acaatcaata cccctggcat aacaggttct
    17941 tctggaaaat gtccttgaaa aaagggctca ttgatcgtta catttttctt agcaacgatc
    18001 cgttctcctt caaccatttc ttccactcga tcaatcaaaa gcattggata acgatgtgga
    18061 atgatttctt ttatttcttg tatgttcatt gttttccctc tttcctgctt tgcttatttt
    18121 tgctgaatcc taaagagtgg ctgtccatat tcgacaactg actcgttttc tacaaggatt
    18181 tctgtgatca ctccgtcggc ctcactagtt atctcattca tcagtttcat cgcttcaata
    18241 atgcagataa cttctccttt ggcaacttga tcacctactt ttttgaaagc tggtttgtcg
    18301 ggcgctggtt gcagataaac gattcccacg attggcgaaa caacctcgat tccatcaaat
    18361 actgccgatt ctttttcttt cattatttct ggagcagttg ttgcttgttc aggtatgaca
    18421 ttgactggct ccgaaactgg caacgtttcg tttgtttgaa ccatattcat gcctcgactt
    18481 gttttatttt tattcatata caattcaaat tgaccttcac gcaaatcgaa ttccgttagc
    18541 gaggattgat caaattgact gactaattct ctgatttcat tgatatccaa aattattcct
    18601 cccagcgttt catgcacaga accgcattat gtccgccaaa ccctaatgaa ttactcattg
    18661 cataagtaaa acttgcaggt ttgctttcgt ttttgacaac tgtcaagtca atctcaggat
    18721 cttgtttttc tacattgatc gtaggtggga taaattgatg ttctaatgcc agcaaagttg
    18781 ccaaggcttc gatcccgccg gctgctccca ataaatgtcc agtcatcgat ttcgtgctgc
    18841 tgacgtaagt atctctgaaa ttttcaccta atgcgatttg gattgctttt gcttctgcct
    18901 ggtcattggc tggtgtactt gttccgtgag cattgatata tccgacttgt tccggctgta
    18961 caccagcttc ttccatcgca agcttcattg ctttagatgc accagaacca tctggagtag
    19021 gagctgtcat atggtaagcg tcacagtttg caccgtatcc aacgatttct ccatagattt
    19081 tggcaccgcg agcttgtgca tgttctaaag attcaagaac tagaacgcct gctccttcac
    19141 ccatcacaaa accattccga ttttcgtcaa acggaatcga accacgatta ggatcagttg
    19201 attctgagag tgctgttaaa gctgcaaatc cagcaatccc catctcacaa atcgttgctt
    19261 ctgttcctcc agcaagaatg acatcagaat agccatgttt gatgttacgg aatgcttccc
    19321 caattgaatt cgttccgcta gcacaagctg ttacgatagc tgtacaaata ccttttgcac
    19381 ctacacgcaa agcaatattt ccagctgcca tgttggcaat cgccattggt acgaacattg
    19441 gagaaactcg ttttgcacct ttttcatgta gacgaataac ttggttttcg attgttggaa
    19501 gaccaccgat cccagatccg atgatgacgc caaaccggtc ttgattcatt ttttctttat
    19561 ctaaaccgct catctccatt gcttctaaag cagcgtagat tccatagatc gaaaacatat
    19621 ccattcgttt gctatctttt ttaataaaat atttatcgta agggaaatct ttgacttcac
    19681 ccgctaaggt aatccctgtt tctgaagcat caaatttagt gatcggtgcg atgccattcg
    19741 tcccctcttt taagctattc aaaaagctgt ctgcgtcatt tccaataggt gaagtgactc
    19801 catagccagt aattaccact cgattcattt gtttgctctc cttttcttat ccgtgcatga
    19861 ccaatccgcc atcgacattg atgacttgtc cggtgatata tggattttgt gctaagaaaa
    19921 ctgctgtttg tgcaatatct tctacttgtc cgaaacgctg catcggaatt tgcttttccg
    19981 cttgttcctt gactttgtct gctaaaactt ccgtcatatc agttgtgatg aatcctggcg
    20041 caatggcatt acatgtaatg cctctagttg cagcttctcg tgccacagat tttgttaatc
    20101 ctactacgcc agctttacta gctgcataat ttgcttgacc aatatttcca atcaacccag
    20161 atacactaga gagattaatg atggcccctt ctcgctgctt catcattttt ttcaatacgt
    20221 gctgcgtcat attgaaggtt ccaatcaaat tgatatccag acattttttg aaatcttctg
    20281 catccattcg catcacaagt ttgtcatttg tgattccggc attgtttact aacacatgga
    20341 tcgatccaag cttttcttct gcttctttga tcatttgtcc cgctttctca taatcagaga
    20401 tgtcaccgga aactcctacg cattttacac cgaatgcttc gatttcttct atcttttctt
    20461 ttggaatctc tccgcgacca ttcaaaatga tatttgctcc agcttttgca aaagctaagg
    20521 ccatcgcttt gccgattcct cttgtactac ctgtgataaa tacatttttt ccttttacat
    20581 ccataacgtt cctccttata gtattgctat tgtttcatca aatgtctgct tattctcaac
    20641 acgcagaact ggtattgttt tatcgatttt tttcataaat ccgcttaata cttttccggg
    20701 gccgacttcg atgacttgtt cgatgccgat tgtttttaac ttatggatac tctcatagaa
    20761 acgaacaggt tgcatgactt gctgttcaag tagtcccgcg attgtttctt tcttcattat
    20821 ttccgttgtt gtgttgctta tgataggaaa agaaggttca gagaattgaa tctgacttag
    20881 gtccttcgcc agtttttttg ctgccggttc taaaatagct gtatgaaaag gcccgctgac
    20941 atttagaggg atcattcttt tgaacccttt ttcttttaat agtaaaacag cttcgtctac
    21001 tgctttttct tcgccaccaa tcacgatctg ctgaggtgta ttataatttg caggagatac
    21061 gatgccgtac ttgctagctt catgacagct ttcctcgatc gtttcaatcg gcgcattcat
    21121 cactgcaacc attttcccgc ttccagctgg ggcagcttct gtcatataag cgcctctttt
    21181 tgctactaac gcaactgctt cagtgaagga tagcgcatta ctagctacta atgccgaata
    21241 ttctcctaaa ctcagtccta aagctgcatc tgggatgatt ccatgctcct tcaataagcg
    21301 ataatacgcg atgctgactg ttagaatagc tggctgtgta tattgcgtct gatccaaacg
    21361 ttcattttct gtaaagcaaa gttcagccat atcgtagccg agaatctcac ttgcttcatc
    21421 aaatgtctgc tttacaacgg cttcttcata taaatctttt cccatacctt gatattgtgc
    21481 accttggcca ctaaataaga atgctgtttt catgtttttc tccaatatat ccagaatata
    21541 tgtttgattc ttcctattca aaaaggccga gacattccta tttcaggaaa tgtcccagcc
    21601 cccaacctaa ttttaatgat tatgcagttt gtttttctac gtaagtcact aaatcttgaa
    21661 ccgttttgat tccgtcttct gtttcgattt tcacgtcaaa ttcatcttca atttcattga
    21721 tgatttggaa taaatccaag ctgtcagctt ctaagtcttc ttggatgtca gtagtcaatt
    21781 tgatttcttc agtttctttt cctaattctt ctgcgatgat ttcttgaatt ttttcgaata
    21841 ccataataat atattcctcc gatattgttt gctttttatt tttataattt aacagtctac
    21901 aactccatga gaatacttcc ccatgttaaa cctccgccat agcctgtaaa tattactttc
    21961 tgctgttttc ctaaggtgat ctttccacta gaaactgctt catccaataa gatagggatg
    22021 cttgcagcag atgtattccc atatttatcc atattggtca ggaacttttc ttgcggcatc
    22081 tttacttttc gggcaatttt ctcaataatt ctgaggtttg cctgatgcaa aagcagataa
    22141 tcaactggtt tgtctttcat gacttcttgg atattgtttg caacgtctcg tacggcaaaa
    22201 tcaaaaatat ctctgccagt catttgcaaa taatacgaac cttctgaatc ttctgaatag
    22261 aacggatttt tattttgctg gtagccagcg gtcaatgagc tacttctggt accgtcagct
    22321 gctaattttt ctttcagcaa ttttttctgt ggattcgctt ctaagagaat cccacctgct
    22381 ccatcgccaa acaacacagc agtcgtacga tcagaccaat cgattagctt agatagtgtt
    22441 tcaccaccaa tcaccagtcc cttagttgag ccgcagcgga tcattttttc agccatgctt
    22501 aacgcataaa caaatcctga gcacgcagca ctgatatcaa aagcgatagc atgagttgct
    22561 cccaatttcc cttgtacttg tgctgctaca gatggtgtcg tgtaatcggg cgacattgtt
    22621 gctactaaaa taaaatccaa atctttaggg tttagatttt tctgttttat caatttttcc
    22681 gccactaaaa tgcataaatc agaagtctcc tgatttgtta cacatcttcg ttcacgaata
    22741 cccgtccttg acgaaatcca ttcatcagag gtatccatca tcttggaaag atcattatta
    22801 gtaataatct tttcaggaag gacgctggct gttgcagtaa tcattccaaa ttgttccatt
    22861 aaatatcctc acttatagtc ttgcaagaag tcgtgcaagt ttttcagtgc atccagcaag
    22921 gcatgctgtt cctccgtagc cattccgtct aagatgttct tgaccatttc acgatgaaaa
    22981 tgctgatgga cccgaaatag taactttcct tttttcgtta gtcccaactt tacaacgcgg
    23041 cggtcatctt cactgcggat acgttcgaca tagccttttt ttactaactt gttaatagca
    23101 gtggtcaagg tcccaacagt aattgatagt tctttggcta cttctgaagt tgtttttttc
    23161 ttgtacatcc cgattgcctc gatcgtgtgc atctctgtga ttgacagatc tttgaattga
    23221 gattttttca gctcagactc ttcgattgtc aaaatatcat tgaagacact aacaagataa
    23281 tcatttactg tttttaaatc tggttccatg ttccaccgtc cactaattag tttgattatc
    23341 aaatcttttg atgttcaaac tatatcttaa cttttttcaa aatgcaacct taaaagatca
    23401 tttttttact atatgagctt tttttaagat tttactcatt taaaacaact gataaatcag
    23461 catttataat ttcttttatt agaaaaatca tctatctcac atattttgat tatcaaagta
    23521 ttttctgtga acagaactat agaattccct aaaacttgtc cattatttca aaatttgtta
    23581 tagtcttttt attcaaagcg taaaaggaga tcctatgtta aaagaaaaaa tgaaaactct
    23641 ccccatgctg ccgggtgtct atcttatgaa agaccgagat ggtaaggtca tctatgttgg
    23701 taaagcaaaa cggctcaaaa atagagtaag cagctatttt catcagaata aacagcattc
    23761 aaaaaaagta ttacgtatga ttcatcatat aacagatttt gatttcgtcg tagtagacac
    23821 ggaattagat gctttattgc tcgagtgtca attgatccaa cattaccgtc ctttttataa
    23881 ccgacaaatg aattatttca gtaattataa ttatgtacat attaccaata agggatttgt
    23941 attaacagat actcctacgg ctcgaacata cgggcctttt cgtctctata aaaaaatgcc
    24001 gtctattttg cgtataatgg aagaaactta tcaaatgcct tggttgtctg aaattagttt
    24061 gttagctttg cgagtccagc ttcctgacct acaggaaatg acttttgaac agaaaaaaaa
    24121 ggaactccaa gggctgtttc aaggccgaaa taaaaagcta ctgacttact tgaaaaaaag
    24181 acaacaacat ttcatctatc agttgaattt cgaaaaagcc ggtatgcttc aaaaagatat
    24241 cgaattagtt acttatttta ttagacggat ccaggaacaa aagcagtttt taagaacacc
    24301 atcgctcacc ttcagcatgc cattagcagc agatgagagt cagaaaaagc actacctcgt
    24361 ttgttatggt caacttgcag aaacaatgat tacctctggt gacgtttctc ctgacttcta
    24421 ttatgaaaag aaagaagctc atttatcttt gaaacgtcaa ttgtcaaaag aagaaatcga
    24481 tcctgtacaa atcttgatca gttaccgcaa aaaattagaa aaagaacagt ttgaaattga
    24541 actgttaaac aaaaaagaag ctgaaaagca actaaattag ttgcttctcg gcttctttta
    24601 ggcatcttca acttcaaatg tcaattatcc taaaatttat tggattaagt catagatttc
    24661 catcgctacg atatcgatat tatcaaattc gtattgctga tgagtatctg tttcagttaa
    24721 ttcaaatgta tcggtcgctt tatcataagt tactgtacac ttctctacgc cttctttttc
    24781 aaaacggcga acttgcagtt cattatctgc tgactcgacc atagcctcca gtcgttttat
    24841 gattgcgact aattgtgaat gtgtcatcgg aggtcctcct tttcttattt ctgttatatt
    24901 gtatcaaaag catagcctac ttgcattgat tttctctaaa aaaactcgtt ttttatgatt
    24961 ttttttctgg tatttttcct tcaggccacc aaagtttgat caaagcttgg gttccgtcat
    25021 tctcaaaacc tttatctgcc aactcttcat atagtttcaa tgcttgggta gttgctggca
    25081 atacaagatc cattttttct gcttcttcta atgcaatctt taaatctttg ataaaatgtt
    25141 tgacaaaaaa accaggtgtg taatcttctt ttaaaatacg aggagaataa ttgcttaaag
    25201 accagttagc tgcacttcca cctgaaagcg tctcaatcac tttctttaaa tcaagtccgt
    25261 ttttttgtgc atagacaagc atttccgtca ttcctgtcat cgtacctgca atcatgatct
    25321 gattagccat ttttgtatgc tgacctttcc cagcagaacc atgcaatgta aatgtcgtac
    25381 caaattcttt gaataaaggc agtacttgat cataaacggc ttcttctcca ccgaccatga
    25441 tcgtcagtgt accattcttt gctcctaagt caccaccgga taccggtgca tctaacgcat
    25501 ctgcgccttt ttcttttgct gtttttgcaa ttttttctgc caggcttggt gtacttgtag
    25561 tcaaatcaac taaaatatgt cctgagatat ctgcagaaaa aatccccgac tgtccatagt
    25621 agatttcttc tacatctttg gggtaaccta ccattgtaaa gagaatatta ctttgttctg
    25681 ctaccgcttt tggtgtatct gcccagatag ctccttctgt tactaaagga tcagcttttg
    25741 cttttgtccg attatagaca gctacttcgt gtcctgcttc tagtagatgg cgtgcgacag
    25801 cacttcccat gacgcctgtt ccgataaaac caagtttcat tttttcgacc tcctaaaaat
    25861 caaaaatcct tgcttctatg ctagtatacg ctagaaacaa ggattttttc ataaaaaatg
    25921 tttgaatttt atcttttaaa tgaatttaat tttattttga ttcgttcaat cgagtcttct
    25981 tcttcttttc ttcgcatctc ttcttcatga taaacaacca tgtcttgata aaattcgatc
    26041 atagcttcgc cgaaatgtgt agatgaaata tcataaagtt tagcttctaa aacttttgga
    26101 tctttaggaa cttcactgga aatataatca ataagtgctg gtgcaaagtc ttcgtcggtt
    26161 tcaaaagttt tccctaatga aggatgatcg aacaatcggt tcaaataagc atttccttcc
    26221 acgacacaag gtgttccggc tgccatcgct tctgtataag taagcccttg tgtttctgaa
    26281 gtagaagcac tgacaaaata atctgccgct ttataataaa gtgctacatc attgttgtcc
    26341 acttctcctg tgaactgcac aaattcttct aactgcagtt ctgagatcaa ttcctctaac
    26401 tcttctacat aaggtccttt tcctacgata actaatctgg cgttaggata agcggagatg
    26461 acctgaggaa acccattaat caaggcttgg atatttttct cataagaaat cctgcttaaa
    26521 gaaagaatca tcaaatggtt ttcctgaaga cctagtgact cccttaattt gctgatatcc
    26581 tgctgagtga tatcagaacg tttgaatttt tcaatgtcga taccagtagg aatcacgcga
    26641 agcggtgcta ttacaccata gctgcgtaat gtatcaataa cacgttcact tggacaaact
    26701 acacctgtcg tatgatttgc aaataatcta gacaagtatt ttacatggga ttgcctgatc
    26761 acttttcctt taccgatata atgaaggtag tcttcataca tcgtatggta agtatggatc
    26821 agaggtattt tcaacttctt agctaccatc ttcccaagta tccctgctcc gaattctgta
    26881 tgggtatgaa taagatctag ttctagttct ttggcaacca aataagcata ccacatgcct
    26941 ctaacaacaa ctcttcgatc cttgaaagaa ataaatggta cacttggcat tcgaatcaca
    27001 tctttttcca acttatccgc attaggatcg gtcgttgtaa aaatatagac ttcatgccca
    27061 tgtctttcta attcttgttt taatgttttg atcgatgtag caactccgct gacttgcgga
    27121 aagtaggtat cggtaaaaaa gccgattttc atgtttttcg cctccaaact agtccttgac
    27181 ctgatttact ttttttaatt tgctagagac tttttcattc agtacacttt cgtatacatt
    27241 tttaagttct tcaccgattt tattgatact tcgctctttt gctgtttgat aaccggcttg
    27301 tgtcgtactc ggtagttctt gattggtaat ctgttggatc agtcggataa attcttcgtt
    27361 tgtcttcccc atatagcagt tcttgctatc ttctaaccag ccattataca ctggaatatc
    27421 tcgaacaagt acgttttgtt tgcttgctaa agcttctaaa acaacgatcc cttctgtctc
    27481 ttcataagaa gggaaaaaga atagatctgc acctgaatac gcaccttcta tgatctctcc
    27541 acgaatgtaa ccaggaaaca ggacattttc aggatgatct tcttttacaa ttttccggat
    27601 gttccgagga atcgagtaca tgggaacatg accaaaccaa ataaatgtgt attcgggcat
    27661 cttcttagca atttctacga aatcaatgat tcctttacgt tcgaaaaaca aaccgacaca
    27721 aatgattact ttttgatccg gagacagttt gaaatattct ctgaactttt gttctttcat
    27781 tggatcaggg tgatatttct ctaagtcgat cccattggaa atagcttgaa tcggcacacg
    27841 gataccatag ctttccaaca actgttttga ataaggtgtt ggcgtgatca gatagtccgc
    27901 tttttggtac aatcctacca gatatttttt tacgatagga gaaagctggt tcgatctgat
    27961 aaaggaattt cggaaatctt cctctgtaga atgcgcatga tagacaactt tttttccttc
    28021 tcttctggct ttattgacca tattatgact attgattccg tatgtattga tgtgcaggat
    28081 gtcataatct tctttttcat ctagtgtata agagataccg acttccgtca gagcacgttt
    28141 ttgatgatca agcgcacgcc cgattccaga ttttgcaagc atcttttcac tttcaaaata
    28201 taataatacc ttcaccttac gtcccccttc acttatatag tataacatag cctacaaact
    28261 gtcactcaaa cttaagccct atttttgtct attcttactg acaaaaacgt tttcttaaaa
    28321 aagaacaaaa aaactggcgt agctctttta caagccacac cagcttttga tacgttgttt
    28381 attttacata ttcatgaaca agttcaacga cttcttccat catatcgcat tctttcaatg
    28441 cacgatcagc aagttcagcc attttcgctg tgtccaagcg tttcattaaa ctacgcgttt
    28501 taagaataga tgtcgcactc attgagaact catctagacc catacctact agcaatggaa
    28561 cagctgtttg atctccagcc atttctccac acatacctgc ccattttcct tcagcgtgtg
    28621 ctgcatcaat tacatttttg atcaaacgta aaattgatgg gttatatggt tggtacaagt
    28681 aagaaacgcg ttcgttcata cggtctgctg ccattgtgta ttgaatcaaa tcgttcgtac
    28741 ctacagagaa gaaatctact tcttttgcaa acttgtctgc taagactgct gctgctggaa
    28801 tctcgatcat gatgccgact tggatcgtat cagatacttc cttgccttca cttatcaatt
    28861 tttgtttttc ttcttcaaag atcgcttttg ctgcgcggaa ttctttgagt gtagctacca
    28921 tagggaacat gatacgtaaa ttaccatgaa cagatgcacg aagcaatgca cgcatttgtg
    28981 tacggaacat ttcgtcgcct tgttcagata aactgatacg caatgcacga tatcctaaga
    29041 atggattcat ttcatgaggt aattgcagat atggtagttc tttatctcca ccgatgtcca
    29101 ttgtacgaac aactacaggt tttccttcca taccttctaa tacagctttg taagcttcat
    29161 attggtcatc ttctgttggg aagtctggag aatccatata caggaattca gtacggtaca
    29221 gaccaactgc ttctccacca ttattatgga caccaactag atcttttggt gttccgatgt
    29281 ttgcagctaa ttcaaaatgc ttgccgtcag ctgtgacagt ttctgcattt tttaattttt
    29341 cccattctgc tttttgtgct gcgtaatctg cacctgcttt ttcaaattca gctttttgtt
    29401 catctgtagg atcgatgatt acatcgcctt cgatcccgtt gacagccaaa atatcgcctt
    29461 ctttgacttt agcagtaatt tcttttgtcc caacgattgc tggaatttct aaagaacgtg
    29521 ccatgatagc agaatgtgaa gtacgtccac caatgtctgt tacaaacgct tttacaaaat
    29581 tgcgatctaa ttgtgctgta tcacttggag tcaagtcatg tgcaacaacg accacttctt
    29641 cgttgatcat tgatggattt ggtaaagtaa cgcctaataa gtgcgctaaa atacgtttag
    29701 caacgtcacg aatatctgca gcacgctctt gcatataagc attatcttcc attgcttcga
    29761 acataccgat atacatatcc gttacttctt ttagcgctga ttcagcattt acgctgttgt
    29821 ctttaatatt ttgcttgatt tgacctacca tttctggatc tgaaagaacc atcaaatggg
    29881 catcaaatac ttgcgcttct gcttcaccta agctttgcgc tgctttttca cgaatttgct
    29941 gcaattcttc agtagattta gctaatgcag catccaaacg agcttcttca gccgcagtat
    30001 cttctactgt tgccttactg aatgttaaat ccggttgaac tagcaggtaa gcttttgcaa
    30061 cggctacacc gtcactagcg gcaatccctt ttagcatttc aaccattatt cagataagcc
    30121 ttctttcttc attgtttcaa cgattgctgc cattgcatca gcttcgtcag caccttctgc
    30181 agtaatagta acatcagaac cttgacctac acctaaagac ataacgccca tgattgattt
    30241 caagtttact gatttacctt tatactctaa gtttacatca gagttaaatt tgcttgctgt
    30301 ttgtactaat agtgtagctg gacgagcgtg gatcccagtt tctgctacta cgtgaaattc
    30361 tttcttttcc atattaatcg gtctccttta agtgagtgtt gtttttatgt gagggttttc
    30421 ttttttagta attcagagaa tcctaacaaa tgccaccctt tcatctgtaa agattaacat
    30481 tttttttcgt tagatacaac agttttcatt caatttcaga taaaagtatt caaattattc
    30541 cggattcttt ttcatccttt tcttcacatt ttataacaaa cgtgtttatt tcctttttct
    30601 tgtcgctttc tcttctcctg acgtttatca ttctttcctt tgaccctctt tgttttcata
    30661 tgaaacgaat tacttgcttc cctttttatt tttagtataa taagagtcaa aggtcaggaa
    30721 tggtcaatag agatttcacc ttttctacct cataaatctc ttaaaaaact aggggttatt
    30781 cttttacctc atgaaaaacg agatgtaaaa tatggatgta cccatttttg tgaaaggacg
    30841 tgaatgattc atgctttgtc aaaactgcgg caagaatgag gcaacgattc acttgtatgc
    30901 cactgtcaat ggtcagcgga cacaactcga ttactgtcag agctgttatc aaaaaatcaa
    30961 aaatcaacaa aatggaggtc tgactaatat ggcccaaaat gatccatttg gatttggcag
    31021 tttggacgat cttttccgtt ccatgtctcg ccaaatgcaa cagcaaggaa attatgagca
    31081 aacaccacca acacaatttg gcggaaacaa caacttcaat ggtggtcagc cacctcaagg
    31141 caatacagaa ggtttattgg gagaatacgg aatcaatatc acagaacaag cacgacaagg
    31201 tgatatcgat cctgtgatcg gacgcgatga cgaaatcaaa cgagtcattg aaattttaaa
    31261 tcgccgaacc aagaacaatc ctgtcttgat tggagaacca ggtgttggta aaacagcagt
    31321 tgttgaaggt ttagcacaaa aaatcgtaga tggtgatgta ccgcaaaaat taatggacaa
    31381 agaagtcatt cgtttagatg tcgtatcttt agtccaaggt actggtatac gaggacaatt
    31441 tgaagaacgt atgcaaaaat tgattgaaga gatccgtcaa gcagaaaatg tgatcctatt
    31501 catagatgaa gttcacgaaa tcgtcggtgc tggttctgct ggtgatggaa atatggatgc
    31561 tggtaatatt ttaaaaccag ctttagctcg aggagaattg caaatggttg gtgctactac
    31621 cttaaatgag taccgcatca tcgaaaaaga cgctgcttta gaacgtcgta tgcaacctgt
    31681 acgggtagat gaaccaactg tcgaagaaac gatcagtatt ttgaaaggtt tgcaaaaacg
    31741 ttatgaagac tatcatcatg taaaatatac tgatgaggcc atcgaagcag ccgcaacttt
    31801 atccaatcgt tacgtccaag atcgcttctt gccggataaa gccatcgatt tgctagatga
    31861 aacaggttct aagaaaaact tgacgatcca aatcgttgat cctaaaacaa tcgagaaaaa
    31921 actgcaagaa gcagaagaac aaaaagtttt agcttctcga gaagaagatt tcgaaaaagc
    31981 agcttattat cgcgatcaga tcaataaact tcaaaaaatg aaagaacgtc agctcactga
    32041 agaggaaaca cctgtgatta ccgaaaaaga tatggaaaaa atcgttgaac aacggacagg
    32101 tattccagtg ggtgaattaa aagaaaaaga acagacacaa ctgaaaaact tagcagatga
    32161 cttgaaagct catgtcatcg gacaagataa cgctgtagat cgagtagcga aagcgattcg
    32221 ccgaaaccgt gttggattaa acaaacagaa tcgtccaatc ggctccttct tatttgttgg
    32281 accaactggt gtaggtaaaa cagagcttgc gaaacaactt gcctacgaac tattcggttc
    32341 acaagattca atgattcgtt tcgatatgtc tgaatatatg gaaaaacata gtgtctctaa
    32401 attgattggt tctcctccag gttatgtcgg atacgaagaa gctggtcaat taacagaaaa
    32461 agtacggaga aatccttaca gtcttgtctt gttagatgaa gtagaaaaag ctcatccaga
    32521 tgttttgcat atgttcttgc aaatcttaga tgatggtcga ttgacagatg cacaaggaag
    32581 aacggtcagc tttaaagata cgatcatcat tatgacaagt aatgccggaa ctggtaaagt
    32641 agaagcaaac gttggttttg gtgcggcacg cgaaggtgtt actcgttctg tattgaacca
    32701 attaaacaac tactttacac cagaatttct gaaccgtttt gacgggatca tcgaattcag
    32761 tgcattatca aaagaaaact tgatgacaat cgtcacacta atgctagacg atgtcaacca
    32821 aatgctggca gcacagcaac ttcacatcga agttcctacg aatgtcaaag aaaaattagt
    32881 tgacttaggc tatgatccat ctatgggtgc tcgtcctctt cgacgcacga tccaagaaca
    32941 aatcgaagat ggtatcgctg aattttatct tgatcaccct tctatccatg agttgaaagc
    33001 aaaactggat aaagatggaa aaatcatcgt tacttctaaa ccagaacgtt tggctaaaga
    33061 atcagccgaa gaaacggctg aataaatcca gttttatagc gtgagacggt atttctttga
    33121 gaaatgccgt ctcattcttt tttcagaaaa gtcaaaatac tgttcatttt ataaaaaaga
    33181 aattataata agagaaacaa gcaattaaaa atacataaaa gaggtgagcg ccatgaaatt
    33241 ggtaaatgta acaaacagcc attcccgtct tgtattaaac cagcttgaaa acactgatgc
    33301 ccatctagtc aaggtctaca cagccggaaa taccactatt gtctacactg aagcccctga
    33361 acataatgaa attctgctga tcaatgacaa acgtaaaatc cagccgaaag aaatcgaaga
    33421 tgctaaaaat tatttcttag ataaaatcaa agacgccgtt taccacgagg atgaaatcaa
    33481 agtaatcgaa ttggcaggcc ttgttgaaat ctcgattcca aaacatgaat taggcgctac
    33541 attagccgtg taaacaaatt ttgaacataa taattaaaga gcgtgggaca aaagtaaaga
    33601 acacttttgt ctcacgctct aaacacgtat aaacggcgaa agcagaagca actccttcgg
    33661 aaataagctg aaattcacga aaattgcttt tcaaattttt gtgaattcca gcttatttct
    33721 tggagttaaa cgcttctgtc tcagcctctt tttctttcta gctttttgat ttttctcttt
    33781 tcttttgtac ttttctcttt tcattttcag ttctacgcgt gtctttattt ttaacttttt
    33841 cctctttatg gatgattgat cgtacttttt gtgcaatttg ctcgtttttg tcccagtctt
    33901 ttacatctaa taatcgacat aatcgtaaca tctcttcttt tttctgtttt tttctttcac
    33961 gtctttgcca ttctgtttcc atgtgtcaca ctctcctttc tttaatcata tgtacgcaaa
    34021 ataattttta tatttttttg attagacatt tctatgattt taatatagta aaaagagccg
    34081 tcacggaaaa tc
//
LOCUS       DAZKKZ010000031        33043 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.031, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000031 DAZKKZ010000000
VERSION     DAZKKZ010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 33043)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33043)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33043
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.031"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(101..1003)
                     /locus_tag="ACG8LA_001517"
     CDS             complement(101..1003)
                     /locus_tag="ACG8LA_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFQ0203822.1"
                     /translation="MNIQQMKYVVAVANNGSFREAAKKMFVSQPSLSAGIKELETELG
                     ITLFTRTNRGAYLTEEGQDFLNRAEKILVQLDTLETHYLTSEKRDNFSIAAQHYDFLG
                     PLTAQLLEEFKDEIKQFRIMETTTARVIEEVKEQHSEIGIIYMNEHNQAGIRRYLQQG
                     ELSGRSIGKFKTHIFLRQGHPLAEHAEITKEELLSYPQVRFTQDGNNFPYFYEDLIEI
                     PDQETVIYTSDRGTLMNIVLETDAYASGSGIVIGGIREHLRLIPLAEGELNEFYIIYS
                     AKRPLSEIAQRFIKELTRLLDQQS"
     gene            complement(1000..1692)
                     /locus_tag="ACG8LA_001518"
     CDS             complement(1000..1692)
                     /locus_tag="ACG8LA_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase family protein"
                     /protein_id="HFQ0203823.1"
                     /translation="MDVEWGYSGDKGPENWASLCDWFARGAEFPLQSPIHLTKGEETK
                     IEGDTLSFHYQKQRFTDKEFKNTIHLVPFDQLSYVEFKKERYYLTDIHFHLPSEHIIN
                     GKQEDIEFHFVHMNSKKENLVVGVMYQLMVQEGWLYNQENGESWNLEKHEHWVNPDVF
                     FPEQKSHFHYIGSLTTPPTSGPIQWFVMDHVGKLNQEFLLPFDGQYARPNNRPIQPLN
                     GREIYYFEEFEQ"
     gene            complement(1735..2376)
                     /locus_tag="ACG8LA_001519"
     CDS             complement(1735..2376)
                     /locus_tag="ACG8LA_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfbR-like 5'-deoxynucleotidase"
                     /protein_id="HFQ0203824.1"
                     /translation="MGLNEFILGLNNLETITRAPGFFKYTEHTVAAHSYRVASIAQVL
                     GDIEEANGQPIDWKLLYEKSLNHDYTERFIGDIKTPVKYASKELRGMLQTVEEKMTDE
                     FINQEIPAEFQEVYRRRLFEGKDETVEGELLAISDKVDLLYESFDEIIKNNPEKVYKE
                     MFIEAVTTIKSFEHRPSVQYFFKEIFPELLNQEFYGKEAFLETVSTIVKKEEK"
     gene            complement(2414..2728)
                     /locus_tag="ACG8LA_001520"
     CDS             complement(2414..2728)
                     /locus_tag="ACG8LA_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0203825.1"
                     /translation="MADLSALDEDREIRFVSPESSIGIAKIQKLIARSIFSSGMKRNF
                     YRDQFLIFLKFIFLRLVSRKKRIISSLFSIIYRFSLFFGKGAVSKMVKSGNVANISYL
                     MI"
     gene            complement(2716..3345)
                     /gene="pyrE"
                     /locus_tag="ACG8LA_001521"
     CDS             complement(2716..3345)
                     /gene="pyrE"
                     /locus_tag="ACG8LA_001521"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004588 - orotate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009220 - pyrimidine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HFQ0203826.1"
                     /translation="MNVEQSIAKDLLEIEAVFLNPSNPFTWASGIKSPIYCDNRITMS
                     YPKVRKEIAKGLASKIKEAYPEVQVIAGTATAGIPHAAWVAEILDLPMVYIRSKAKDH
                     GKGNQIEGRIFEGQKMVVIEDLISTGGSVLEAAEAAKREGADILGVAAIFTYELPKGK
                     ANFEKAEIPLMTLTNYSVLIEAALEDRYIDEQELTLLKEWKKDPENWQI"
     gene            complement(3352..4068)
                     /gene="pyrF"
                     /locus_tag="ACG8LA_001522"
     CDS             complement(3352..4068)
                     /gene="pyrF"
                     /locus_tag="ACG8LA_001522"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004590 - orotidine-5'-phosphate
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0044205 - 'de novo' UMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HFQ0203827.1"
                     /translation="MNQLDQRPIIALDFSTRQEVEDFLRFFPKEEKLFVKIGMELFYQ
                     EGPEIVRYLKEAGHNVFLDLKLHDIPNTVEKAMRGLAKLGVDLTCVHAAGGIRMMEAA
                     MRGLEEGTPEGGKRPLLLAITQLTSTSEEEMHADQLIEVSLEKSVIHYASCAKKAGLD
                     GVVSSAWEVEAIKEMAGDEFVCLTPGIRPEGTVAGDQTRVVTPSQAKKIGSTFIVIGR
                     PITQSTNPYKAYQTIQTEWS"
     gene            complement(4065..4997)
                     /locus_tag="ACG8LA_001523"
     CDS             complement(4065..4997)
                     /locus_tag="ACG8LA_001523"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004152 - dihydroorotate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HFQ0203828.1"
                     /translation="MNENPLAVKLPGLELKNPIMPASGCFGFGKEYGKYYDLNQLGSI
                     MVKATTPNARFGNPTPRVAETPSGMLNAIGLQNPGLDVVMHKLLPELEEYNELPIIAN
                     VAGACEEDYVEVCSKIGEAPNVKAIELNISCPNVKHGGIAFGTDSDVAFQLTQAVKKV
                     SSVPVYVKLSPNVTDIVPIAQAIEAGGADGFTMINTLLGMRIDLKTRKPILANQTGGL
                     SGPAIKPVAIRLIHQVASISSLPIIGMGGVQTVDDVLEMFMAGASAVAIGTANFTDPY
                     ICPKLIKELPVRMSELGIESLERLIKEVREERER"
     gene            complement(4994..5770)
                     /locus_tag="ACG8LA_001524"
     CDS             complement(4994..5770)
                     /locus_tag="ACG8LA_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HFQ0203829.1"
                     /translation="MKQEMMEIVQQKQLAPKIFEMTLKGDLVKEMQQPGQFLHILVPR
                     ADLLLRRPISLNHIDHETNTCRIIYRVEGEGTRVFSTLSAGDHLDVMGPLGNGFDLSN
                     LHTGDEVFIIGGGIGVPPLYELSKQLVEKGIKPTHFLGFATHEVVYYEKEFNRLGETR
                     IATDDGTYGMHGNVGNLLLGTKTEPTAVFACGSNGLLKTVEQLFSSHQNVQLSLESRM
                     ACGIGACYACVCHTPEDETGTKSVKVCDEGPIFKIGEVII"
     gene            complement(5824..9009)
                     /gene="carB"
                     /locus_tag="ACG8LA_001525"
     CDS             complement(5824..9009)
                     /gene="carB"
                     /locus_tag="ACG8LA_001525"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HFQ0203830.1"
                     /translation="MPKRTDIKKIMVIGSGPIIIGQAAEFDYAGTQACLALKEEGYEV
                     VLVNSNPATIMTDKEVADQVYIEPITLEFVSRILRKERPDALLPTLGGQTGLNMAMEL
                     AASGILEELNIELLGTKLSAIDQAEDRDLFKQLMKELNQPIPESEIVNTVEEAVDFAN
                     KIGYPVIVRPAFTLGGTGGGMCENEEELRIVSENGLSLSPATQCLIERSIAGFKEIEY
                     EVMRDSADNAIVVCNMENFDPVGIHTGDSIVFAPSQTLSDHEYQMLRDASLSIIRALK
                     IEGGCNVQLALDPHSFNYYVIEVNPRVSRSSALASKATGYPIAKLAAKIALGLTLDEM
                     KNPVTGTTFAEFEPALDYVVAKIPRWPFDKFENGERLLGTQMKATGEVMAIGRNIEES
                     LLKAVRSLEIGTHHIELPELADITDDDLIQKVVRAQDDRLFYVAEAIRRGYTIEELAD
                     LTKIDLFFLDKLLHIVEIEQQLKQQPLDDKILKTAKQNGFTDKKVAELWEINEEAVRQ
                     MRKENDLIPVYKMVDTCAAEFESKTPYFYSSYEYENESSRSEKPSILVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQQAGYEAIIMNSNPETVSTDFSISDKLYFEPLTFEDVMNVIEL
                     EQPIGVIVQFGGQTAINLAEPLTAAGVKILGTTIEDLDRAENRDLFEQALKELDIPQP
                     LGDTATSKEEAVVIASRIGYPVLVRPSYVLGGRAMEIVENQRDLEDYMEHAVKASPEH
                     PVLVDRYLLGGECEVDAICDGETVLIPGIMEHIERAGVHSGDSMAVYPPQTLSESIKK
                     TIEDYTIRLALGLNCVGMMNIQFVIHENEVYVIEVNPRASRTVPFLSKVTGIPMAQIA
                     TKAILGEKLKTLGYENGLYPETKEVHVKAPVFSFTKLQKVDTYLGPEMKSTGEVMGSD
                     RQLDKALYKAFEASGLHLPEYGAVLFTIADETKEEALELAKRFTEIGYSLIGTKHTAA
                     YFEKNGLVVETVAKISEEAAEKNVVDLIRDGKTQVVVNTIDKDRGNASKDGFIIRREA
                     VEHGIPLFTSLDTADAIVRVMESRAFSTNPI"
     gene            complement(9014..10090)
                     /locus_tag="ACG8LA_001526"
     CDS             complement(9014..10090)
                     /locus_tag="ACG8LA_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004088 - carbamoyl-phosphate synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006541 - glutamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl phosphate synthase small subunit"
                     /protein_id="HFQ0203831.1"
                     /translation="MERLLILEDGTVFEGKAFGADASVFGEIVFTTSMTGYQETITDQ
                     SFNGQIITFTYPMVGNYGVNRDDYESISPTCKGVVVKEHARVASNWRNQMTLDSFLKQ
                     KGIPGISGIDTRALTRKIREVGTMKASIVDAGDSFEHAFDQLKATVLATNQVQQVSTN
                     KPYPSPGTGRKVIVIDFGLKHSILRELSKRNCNLTVLPYNTDAETILALSPDGVMLTN
                     GPGDPKDVPEAIEMIKKIQGKVPIFGICLGHQLFALANGADTYKMKFGHRGLNHPVRE
                     VATGRIDFTSQNHGYAVDEATIDPEKLIVTHVEVNDGTVEGVKHRDYPAFSVQFHPDA
                     APGPHDALHLFDEFMEMMDAGKEQ"
     gene            complement(10095..11375)
                     /locus_tag="ACG8LA_001527"
     CDS             complement(10095..11375)
                     /locus_tag="ACG8LA_001527"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004151 - dihydroorotase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HFQ0203832.1"
                     /translation="MKTLIKNGQINTRKNMTTPAEIWIEDGRIKAIGTGFSEAEFDEV
                     FDAKGQLITPGLVDVHVHLREPGFTYKETIEAGTRSAARGGFTTVCAMPNLNPVPDTA
                     EKLRQVYDIIRKDAVVKVLQYAPITENLRSEKLVDQEALIEEGAFAFTNDGVGVQTAG
                     TMYLAMKEAAKNNKALVAHTEDESLLFGGVMHAGKKAEELGLPGILSVTESSQIARDL
                     LLAEATGVHYHVCHVSTKESVRVIRDAKKAGIHVTAEVSPHHLILIDEDIPEDFGFWK
                     MNPPLRGREDREALIEGLLDGTIDCIATDHAPHGLEEKSQSFMKSPFGIVGSETAFQL
                     IYTHFVETGRFTLEQVINWLAVKPAEIFGLNAGTLTVGAPADVAVFDITQTCTIDKED
                     FLSKGENTPFIGWKVKGETQMTFVNGKLVWQKGE"
     gene            complement(11394..12320)
                     /locus_tag="ACG8LA_001528"
     CDS             complement(11394..12320)
                     /locus_tag="ACG8LA_001528"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004070 - aspartate carbamoyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0016597 - amino acid binding [Evidence
                     IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HFQ0203833.1"
                     /translation="MIIKSERISLKHLLTVEALTDQEVMGLIRRGQEFKQGANWTPQK
                     RQYFATNLFFENSTRTHKSFDVAEKKLGLEVIEFEASTSSVQKGETLYDTVLTMSALG
                     VDVAVIRHGDENYYDELIQSKTIQCSIINGGDGSGQHPTQCLLDLMTIYEEFGHFEGL
                     KVAIVGDITHSRVAKSNMQMLKRLGAQVFFSGPREWYDDEFEVYGHYMPLDELLDQVD
                     VMMMLRVQHERHDGKESFSKEGYHQEHGLTVERAKKLQKHAIIMHPAPVNRDVELADS
                     LVEGLQSRIVQQMSNGVFVRMAILEAVLNGKA"
     gene            complement(12333..13616)
                     /locus_tag="ACG8LA_001529"
     CDS             complement(12333..13616)
                     /locus_tag="ACG8LA_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="solute carrier family 23 protein"
                     /protein_id="HFQ0203834.1"
                     /translation="MSEKKGFHNDDVVLDIHDRPTPGHWVGLSLQHLFTMFGATVLVP
                     ILVGIDPGIALVSSGLGTLVYLFTTKGKIPAYLGSSFAFIAAMQLLMKTDGYPAIAQG
                     AVTTGLVYLIVALIIKKIGSAWLDKILPPIVVGPVIMVIGLGLAANAATNAMYNQGTY
                     DFKYIAVALITLGLTIFFNMWLRGFLGLIPILLGIISGYIVALLFGIVDTKPIVDAAW
                     FAVPNFEIPFVQYEPKLYLGAITTMAPIAFVTMTEHIGHLMVLNKLTKRNFFEEPGLH
                     KTLTGDGLAQIVAAFVGGPPVTSYGENIGVLAITRVHSVFVIGGAAVFAVILGFVGKL
                     SALILSIPGPVISGISFILFGVIAASGMKILIENKIDFDKKKNLLIASVILVVGIGGL
                     VFEVGTFTLSAMALATVLGIILNLILPETSRSEEN"
     gene            complement(13630..14169)
                     /gene="pyrR"
                     /locus_tag="ACG8LA_001530"
     CDS             complement(13630..14169)
                     /gene="pyrR"
                     /locus_tag="ACG8LA_001530"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HFQ0203835.1"
                     /translation="MQAKEVVDQVTMKRALTRITYEIIERNHSIQDIVLVGIKTRGIY
                     IASRIAERLKQLEDIDIPVGELDITLYRDDKKENPEEPELHSSDIPVSLEGKEVILID
                     DVLYTGRTIRAAMDAVMDFGRPRKISLAVLVDRGHRELPIRADYVGKNIPTSRAEEIL
                     VEMQELDGQDRIMILKEED"
     gene            complement(14404..15315)
                     /locus_tag="ACG8LA_001531"
     CDS             complement(14404..15315)
                     /locus_tag="ACG8LA_001531"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HFQ0203836.1"
                     /translation="MTELKTTIHHESGRIDKVLTNLFTDYSRSQIQLWLKNGAVSVNG
                     QPVKANYKVKQGDEITVLIPEPETLDVVPENIPLTIVYEDEDVAVINKPQGMVVHPSA
                     GHTHGTMVNALMYHIKDLSTINGVIRPGIVHRIDKDTSGLLMVAKNDQAHESLAQQLK
                     DKTSLRKYVALVHGEIPHEKGTINAPIGRSKENRKMQAIREDGKSAVTHFTVLERFEG
                     FTLVELKLETGRTHQIRVHMKYIGYPLAGDPVYGPKKTLKGNGQFLHAQMLGFTHPTT
                     NEKMIFEAPLPEVFEKTLEKLRKNIAF"
     gene            complement(15312..15776)
                     /gene="lspA"
                     /locus_tag="ACG8LA_001532"
     CDS             complement(15312..15776)
                     /gene="lspA"
                     /locus_tag="ACG8LA_001532"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HFQ0203837.1"
                     /translation="MLIIYWIFSALLVGVDQLVKWWITDNLALGETKNLIPGILSLNH
                     IRNTGAAWSMLEGKMWFFTIVTLIAVVVILTLMIKNREKGNRWFMIGLSLILAGAIGN
                     FIDRIRLGYVVDMFQTDFMSFPIFNVADVTLVCGVICMLIYIILDEKDQRKK"
     gene            complement(15781..16479)
                     /locus_tag="ACG8LA_001533"
     CDS             complement(15781..16479)
                     /locus_tag="ACG8LA_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HFQ0203838.1"
                     /translation="MANSDLFLISFNRIEKWMRDEMGNARNMGFTELVRRLAQRKQLM
                     IRKYEDDLLQLAQLRNAIVHDRIAVDFVIAEPNDWTVKRIQLIEQELIQPETVLPRFA
                     KRVTGFEQDLPLLELLKIVAEKRYSQFPLYNKGKFVALITLRNIGFWLAKESQKGPVD
                     LTNKRALDLIIQNGKYTNYHFVPAKTHIYEVEAMFREQGTLEAVLITKDGNPDGNLLG
                     IVRPRDIYKQIEKD"
     gene            complement(16466..16852)
                     /locus_tag="ACG8LA_001534"
     CDS             complement(16466..16852)
                     /locus_tag="ACG8LA_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0203839.1"
                     /translation="MKTTFIRKTGFYGMGSSIQLRINNEKRSVLSHEQKITLDLEVPF
                     TMQVTFYWLKSPVYTVKEAKPAYVITMNYLILQIYPFLFLATGLGAVFLQNLFFSFFA
                     VIVLIAFFFYIKNRAYLIKEENYGKL"
     gene            complement(16999..18669)
                     /locus_tag="ACG8LA_001535"
     CDS             complement(16999..18669)
                     /locus_tag="ACG8LA_001535"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004329 - formate-tetrahydrofolate ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HFQ0203840.1"
                     /translation="MKNDLQISQETELEPIVEVASKLDLKEDDLELYGKYKAKINFSG
                     INRSKDNAEGHLILVTSINPTPAGEGKSTITVGLGDALNKINKKSVIALREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALLDNHIHQGNELNIDARR
                     VIWKRVVDLNDRELRKVIVGLGGPIQGVPREDGFDITVASEIMAILCLAADLEDLKAR
                     LARIVVGYTFDRQPVTAGDLKAEGALALLLKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSILATKTALRLADYVVTEAGFGADLGGEKFLDIKVPNLKKAPDAVVIVATVRAL
                     KMHGGMKKDELKNENLDALKVGFANLKRHIRNMEQYQLPVIVAINEFVTDTDNELTLL
                     EHLCENQGILAKRASVWADGAEGGVDLAKAVVRLIDRKEANYKPLYRLEETIQEKTET
                     IVKKIYGGNGVVFSKKAQKQIEEFTKNGWDKLPICMAKTQYSFSDDPSLLGAPEDFTI
                     TIREIIPKLGAGFLVALTGDVMTMPGLPKKPAALNMDVTNDGEVLGLF"
     gene            18852..19085
                     /locus_tag="ACG8LA_001536"
     CDS             18852..19085
                     /locus_tag="ACG8LA_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HFQ0203841.1"
                     /translation="MTTGIVKWFDNKKGYGFISYDDTEEIFVHFTAIEEEGFKTLEEN
                     QVVEFEIIEGNRGTQAAHVKKGNVQTTDTSMHE"
     gene            complement(19184..19615)
                     /locus_tag="ACG8LA_001537"
     CDS             complement(19184..19615)
                     /locus_tag="ACG8LA_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EbsA family protein"
                     /protein_id="HFQ0203842.1"
                     /translation="MKKNIRWQPELAHTIIYWSLTLIILFFSLILSLENTGPYWKSNF
                     VLGIFLVFLFLGLRRSFILKSNSVIIRYAAFWKDREISVGQIRSLTPTNTGVQMMLQD
                     EKAPSVFMMRKKDQVVLFDHFEKNGPKSESIPYPYTKKRKS"
     gene            19694..20107
                     /locus_tag="ACG8LA_001538"
     CDS             19694..20107
                     /locus_tag="ACG8LA_001538"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HI family protein"
                     /protein_id="HFQ0203843.1"
                     /translation="MLKVYIDASTKGNPGPSGGGILIVYQGKQEQLSIPLSIGTNHQA
                     EFEVFLKTLEFLKKNDLQNETIFCFSDSKTLVSTVDKNATKNELFLPYLQRIQELLSE
                     FSLLILQWLPENKNKGADNLARQALHKQLKEKKTL"
     gene            complement(20145..21293)
                     /locus_tag="ACG8LA_001539"
     CDS             complement(20145..21293)
                     /locus_tag="ACG8LA_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HFQ0203844.1"
                     /translation="MAKKQEEKKKQIPQQRTKKGVLAGILGLVTNLILFVSKLMIGLF
                     SGSVSIMADAVNSLSDTASSILTLIGFKIAAKPADQEHPYGHERFEYISGLFVSIIIT
                     YVGFQFLESSAEKIIHPENVSLTPIVFFVLIISIFLKFAQGKMYQVIAQSIDSETLRA
                     TATDSYNDVFTTLAVLLSAAIEWVTGWRIDGYIGFALALYILYSGLTMLRNFVYELLG
                     SRPTPAEIEEMEEHLNACDDILGYHDLLVHNYGPNKRFASVHIEVDESMNLNVAHKII
                     DLIEKDFKKSLDVELVCHLDPMPVDNEKYYNILRQLKQILLETGTGLNIHDFRVIHQG
                     KTLQFDVVVPEKFQFVDTELERILRSQIEEKIGDYQLEITFDHNYLLY"
     gene            complement(21415..22011)
                     /locus_tag="ACG8LA_001540"
     CDS             complement(21415..22011)
                     /locus_tag="ACG8LA_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HFQ0203845.1"
                     /translation="MNSRNKTFRLVLRAILLAIIIVQAMVPWLGFIPLGFISLTIIHI
                     TVIIAAVVLGPKDGMVIGLFWGIATIVRAYAMPTTPFDTLVFTNPIISVVPRVLVGLV
                     AGLVFHWIYQKNKSITISSAFAGVLGSLVNTVLVLGFMGLFYTGATADAYGVDSALLF
                     KTLAGVAAINGIPEAIGAGIITPLLAKALFAATPLKPE"
     gene            complement(22211..24853)
                     /gene="alaS"
                     /locus_tag="ACG8LA_001541"
     CDS             complement(22211..24853)
                     /gene="alaS"
                     /locus_tag="ACG8LA_001541"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004813 - alanine-tRNA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006419 - alanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HFQ0203846.1"
                     /translation="MKQLSSAQVRQMFLDFFQSKGHTIEPSASLIPVNDPTLLWINSG
                     VATLKKYFDGSVVPENPRITNAQKSIRTNDIENVGKTARHHTMFEMLGNFSIGDYFKN
                     EAIHWAWEFLTDPKWMAFDPEKLYVTVYPKDTEAKRIWHEEVGLPLDHIIDVEDNFWD
                     IGAGPCGPDTEIFYDRGEAYNDLAEDDPENYPGGENERYLEIWNLVFSEFNHKPDNTF
                     EPLPHKNIDTGMGLERMVSIVQDASTNFETDLFMPIIHAVEKLSKQVKYGENPVTDIS
                     YKVIADHIRALSFAIGDGALPSNEGRGYVLRRLLRRAVMHGKKLGIEQAFLYRLVPVV
                     GEIMVSYYPEVLQQKEFIEKVIRTEEERFNETINEGLEILNQVIQEVKNENGTTLAGK
                     DIFKLYDTYGFPVELTEEVAEDEGLKVDHAGFEKEMDAQRERARSARSTEKSMGVQSA
                     LLTDIKVESKFIGYTEQESDSQLLVIVKGESLLNEVAEGEAQMIFDQTPFYAEMGGQV
                     ADQGWIMNEVGEIVAVVTDVQKAPNGQFMHTVEVKAPMSEGQTYHLLIDQSMRNRIIK
                     NHTATHLLHKALKEVLGEHANQAGSLVAPGHLRFDFTHFGQITSDELAEMERIVNEKI
                     WEAIPVETIETDIDTAKNMGAMALFGEKYGHDVRVVNIGGWSIELCGGTHVANTENIG
                     IFKIVSESGIGAGVRRIEAVTSKEAYELLEEEEKQLKQVATIVKSPQLKEVVSKAEQL
                     QQQVRELQKENEQLASKLANQQAGDVFKDPETINGKTIIAAQVKVKDMNQLRQLADQW
                     KQKNISDILVLANEQEGKVSLLAAMTKESNEAGLKAGDLIKAIAPKVGGGGGGRPDMA
                     QAGGKNPAGIPDALKAAKEWVAQQ"
     gene            25241..25672
                     /locus_tag="ACG8LA_001542"
     CDS             25241..25672
                     /locus_tag="ACG8LA_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFQ0203847.1"
                     /translation="MKKIVGADEWIRAASCFLRYQVFVLEQGIPAELEFDGKDIPQQT
                     YYLFLDQKRPVATLRYEKKTPTCFKPERFCVAKEYRGKGLGGQLLEAAEKRAVSEGCQ
                     TSYVVAEMTAVDFYEKQGYHTCTEPFIEDEVLCIGMKKSLA"
     gene            complement(25717..27066)
                     /locus_tag="ACG8LA_001543"
     CDS             complement(25717..27066)
                     /locus_tag="ACG8LA_001543"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HFQ0203848.1"
                     /translation="MNNFDIFRFKPFINEALTAKGFKQPTEVQERLIPLIAKGKNIIG
                     QSQTGTGKTHTFLLPLFEKINAEKEEVQVVITAPSRELAAQIYEAATQIAKFSTPEIR
                     VSNFVGGTDKQRQLNRLHHQQPQVVVGTPGRILDMMNEQALKIHTAFAFVVDEADMTL
                     DMGFLNEVDQIASRLPEKLQFLVFSATIPEKLRPFLRKYMENPIIEEIKPKAVISEDI
                     ENWLISTKGKDENQMIYQLLTIGHPYLAIVFANTKQHVDEIADYLKNQGLKVAKIHGD
                     ITPRERKRVMRQVQNLEYQYVVATDLAARGIDIEGVSHVINAEIPEDLDFFIHRVGRT
                     GRNGLKGTAITLYSPNDEQAIDAIEKLGVSFEPKEIKNGEIVKTYDRNRRAKREKSKD
                     VLDPTLIGLVKKKKKKIKPGYKKKIDWAIAEKNKKERKIERRQQSRTARKNKKNSHK"
     gene            complement(27136..28299)
                     /locus_tag="ACG8LA_001544"
     CDS             complement(27136..28299)
                     /locus_tag="ACG8LA_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HFQ0203849.1"
                     /translation="MASYIEPIRFALIVFPFLALAISSVFFIYEYRKYGTFLVTRAVI
                     LYSFVFYLLCAYFLVILPLPAKETVAQMTGPKMELHLFASWQHFRDNTVLVLSEPSTY
                     LPAMKQSVFLEPAFNVLLLIPFGIYLRYYFRLSFMKTMIASFCLSLFFELTQLSGLYF
                     IYPRPYRLFDVNDLVTNTLGGIIGFVVTPLFTFMLPTRRRMDELSYEKGKTVSLTRRL
                     VAYLIDWTFLSLINLVAAIFFKIAFDSGAVTSHIWWLLLEVGVYFMIVPFITNGWTLG
                     KKIVRIRLVEEDRERISLKALMIRYGYLYFLFYGLSWLGQLLQQIMNSTTNTVLQMSA
                     VFISLGVLLLQGIFILNILLSFLRKKRILFYEKASHTYTVSTIGQTKDDDSRN"
     gene            28428..28751
                     /locus_tag="ACG8LA_001545"
     CDS             28428..28751
                     /locus_tag="ACG8LA_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0203850.1"
                     /translation="MLNMYFVFGVPIFLLFLYATIAYVRKRTTIHYLGFILLIISGFM
                     LVFNLQTWQQALLEMDKMTPHALSKVLGYPVYLIWLPIFISGCLVLLNIYRGVRRIVQ
                     LRKSK"
     gene            complement(28934..30283)
                     /locus_tag="ACG8LA_001546"
     CDS             complement(28934..30283)
                     /locus_tag="ACG8LA_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HFQ0203851.1"
                     /translation="MEEYQATPVKEVKIENELKRTMGFFTALSTVMGTVIGAGVFFKA
                     ASVAEVTGSASLHMFSWFLGGMISVCAGLTGAELAAAIPETGGMIKYIERIYGNTAAF
                     LLGWAQVVIYFPANVAALSIIFGTQFVNLFGLSQSMIVPVAVTAAVSILLINFLGSKA
                     GGAFQSITLVCKLIPLFVIVIFGLFRQEGVDFQLFPIQAGENLSFFSALGAGLLATMF
                     AYDGWIHVGNISGELKKPAKDLPKAISLGIIGIMIVYLLVNAVFLRTASIDGVAGNSN
                     AASDVAKMIFGGFGGRLVTVGILISVYGTINGYTLTGMRLPYVMAKENNLPFSKLFAK
                     LHDKTKVPVAAGILELVIAIGMMMIGGFDTLTDMLIFVIWIFYTMVFVGVILLRKKEP
                     DLFRPYKVPMYPFIPLVAIIGGTFIVSSTLITQTFLASMGIVLTLAGIPIYLYLKRR"
     gene            complement(30352..31305)
                     /locus_tag="ACG8LA_001547"
     CDS             complement(30352..31305)
                     /locus_tag="ACG8LA_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="HFQ0203852.1"
                     /translation="MKKVLVTGCLGQIGSELITRLRQELGSENVIATDIRMPEVIEKN
                     DIFEILDVMDYEKMRSIAEQYQVDTLIHLAALLSAVAEAKPQLAWNLNVTGLVNALEV
                     AREFQLKFFTPSSIGAFGPNTPKDHTPQDTLQRPTTMYGVTKVAGELLCDYYYVKYGV
                     DTRGVRFPGLISYATLPGGGTTDYAVDIYYSAIKEGKYTSFIDQGTSMDMMYMPDAID
                     AIIKLMNADPDRLVHRNAFNISAMSFDPEEIKASIQKIIPDFEMDYDVDPVRQSIAES
                     WPNSLDVSCAQEEWGFSPKYDLDVMTKDMLEKLKEKLVETV"
     gene            complement(31407..32597)
                     /locus_tag="ACG8LA_001548"
     CDS             complement(31407..32597)
                     /locus_tag="ACG8LA_001548"
                     /EC_number="2.3.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008890 - glycine C-acetyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine C-acetyltransferase"
                     /protein_id="HFQ0203853.1"
                     /translation="MSSKELTMYLEKELDQLKEKGLYNTIDILESENGACIIVDGKKM
                     INLASNNYLGFANREELKKACIEATETYGVGAGAVRTINGSLKIHQQLEEKIAEFKGT
                     EAAIAFQSGFNCNMGAISAVMTKEDAILSDELNHASIIDGCRLSGAKIIRIKHQDMKD
                     LEKKAKEAIESKKYKKIMYITDGVFSMDGDIARLPEIIPIVEKYGLITYVDDAHGSGV
                     TGKGAGTVKHFGLSDKIDMQMGTLSKAIGVVGGYVAGSKTLIDWLKARSRPFLFSTSL
                     TPGAAAAALASITLMQEHPELVEKVWENANYFKEELKKVGYNIGMSETPITPVILGDE
                     KVTQTFSKKLIEHGIYAKPIVYPTVPLGTGRIRNMPTAEHTREMLDEAVAVYQKIGKE
                     MEII"
     gene            complement(32797..>33043)
                     /locus_tag="ACG8LA_001549"
     CDS             complement(32797..>33043)
                     /locus_tag="ACG8LA_001549"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0203854.1"
                     /translation="IRKNRTVTRLLSQSFFRIQQVKLLRNIQRVKLKIADKRRWKFYV
                     FLLVYAINKLNIQNTIDFNERASINGCVVFICPGRVK"
BASE COUNT         9268 a         7258 c         5775 g        10742 t
ORIGIN      
        1 aaattgtttg ctacaaaaag aggagttgtg acaaaattct gtcacaaccc ctcttttttg
       61 atcaacggtg ttcaataaac agcgttctca tctgcttttc ttagctctgc tggtccagta
      121 accgagtaag ctctttgata aatctttgag cgatttcact gagcggacgt ttcgccgaat
      181 aaatgatata aaattcattt agttcgcctt ctgccaaagg gattaaccgc aagtgctcgc
      241 gaatccctcc aatcacaata ccagatcctg aagcgtaagc atcagtttca agaacgatat
      301 tcatcaaagt acctcgatca ctcgtataaa tcactgtttc ttgatcaggg atctcgataa
      361 ggtcttcata aaaatacggg aaattatttc catcctgtgt aaaacgaact tgaggataag
      421 ataacaattc ttctttggtg atctctgcgt gttcagctaa tggatgtcct tgccttaaaa
      481 aaatatgcgt tttgaatttt ccaatgctgc ggccacttag ctctccttgt tgtaaatatc
      541 ttctgatacc agcttgatta tgctcattca tataaataat gccgatctca ctgtgctgct
      601 ctttgacttc ttcgatcact ctcgctgttg tcgtctccat gatccgaaat tgtttgatct
      661 cgtctttgaa ttcctcgagt agctgtgcgg tcaaaggacc taagaaatca taatgctggg
      721 cagcgatcga aaaattgtct ctcttttcac tcgttagata gtgagtttct aatgtatcaa
      781 gctggaccaa tattttctcg gcacgattta agaagtcttg cccttcttct gttaaatatg
      841 cccctcgatt cgttcgagta aacagcgtga tccctaactc ggtttctaat tctttgatac
      901 cagctgaaag acttggctgg gagacaaaca ttttctttgc cgcttctctg aaactaccat
      961 tgtttgctac agcgaccacg tatttcatct gctgaatatt cattgctcaa actcctcgaa
     1021 ataataaatt tctcttccat tcaagggctg gattggtcgg ttgttcggtc gagcatactg
     1081 accatcgaag gggagaagaa actcttggtt cagttttcct acatgatcca ttacaaacca
     1141 ttggattggc ccgctggtag gcggagttgt caatgagcca atataatgga aatggctttt
     1201 ttgctccgga aagaacacat ccggatttac ccaatgctca tgtttttcta agttccaact
     1261 ttccccattt tcttgattat acagccaacc ttcctgtacc attagctggt acatgacacc
     1321 cacaactaga ttctcttttt tgctgttcat atgaacaaaa tgaaattcaa tatcttcctg
     1381 ttttccgttg atgatatgtt cagaaggcaa gtggaaatga atatctgtca aataatagcg
     1441 ttctttcttg aactctacat aactgagttg gtcaaaaggt actaaatgaa tcgtgttttt
     1501 gaattccttg tcagtaaacc gttgcttttg ataatgaaag gaaagcgtgt ctccttctat
     1561 tttggtttct tcccccttgg tcaaatgaat aggcgactgc aatggaaatt ccgcacctct
     1621 cgcaaaccaa tcacataaac tcgcccaatt ttccggacct ttgtctccag aatagcccca
     1681 ttcgacatcc atattctttt tcaactatac ttccccctgc atctcatatc atttttattt
     1741 ttcttctttc tttacaatcg ttgagacggt ttctaaaaac gcctcttttc cataaaattc
     1801 ctggttcaat agttccggaa atatctcttt aaagaaatac tgaacagaag gccgatgttc
     1861 aaagctttta atcgtagtca ctgcctcaat gaacatctcc ttataaactt tttccgggtt
     1921 atttttgatg atttcatcaa aagattcata aagaaggtca accttatctg aaatggctaa
     1981 tagttctcct tctacggttt catcttttcc ttcgaacaac cgacggcgat aaacttcttg
     2041 gaactcagct ggaatctctt ggttgatgaa ttcgtccgtc atcttttctt caactgtttg
     2101 cagcatccct cttaactctt tgcttgcgta tttcaccggc gttttgatat caccaataaa
     2161 acgctctgtg tagtcatgat tcaatgattt ttcatagagc agtttccaat cgatcggttg
     2221 tccattcgct tcttcaatgt ctcctagaac ttgcgcaata gatgctacac gatacgaatg
     2281 tgctgcaact gtatgctctg tatatttaaa aaatccaggt gcccttgtga tcgtctctaa
     2341 attgttcaat cctaaaataa attcattcaa ccccataaaa gttacctccc tttgagattt
     2401 ctttttccga atatcatatc attaaataac tgatattcgc aacatttccg ctctttacca
     2461 tttttgaaac agctccctta ccaaaaaata gagaaaatct atatataata gaaaaaagag
     2521 aagagattat tctcttcttt ctgctaacca gtcttagaaa aatgaatttt aaaaaaatca
     2581 aaaactgatc acgatagaag tttcttttca tacctgatga aaagatgctt ctcgcaatca
     2641 gtttttggat ttttgctatt ccaattgatg attctggaga cacaaatcgg atttctctat
     2701 cttcatcaag cgcgcttaaa tctgccaatt ttcaggatct tttttccatt cttttagcag
     2761 agttaattct tgctcatcga tataacgatc ttctaaagct gcttcaatca atacagaata
     2821 attggtcaac gtcataagag ggatttcggc tttttcgaaa tttgcttttc cttttggcaa
     2881 ctcatacgta aagatagccg caacaccaag gatatccgca ccttctcttt ttgctgcttc
     2941 agctgcttcc aagacacttc cgcctgtaga aatcaaatcc tcgatcacaa ccatcttctg
     3001 accttcaaat atacgtcctt cgatttggtt acctttccca tgatctttcg ccttacttcg
     3061 aatatagacc attggcaaat ccagtatttc cgctacccat gcggcatgag ggattcctgc
     3121 tgttgcagtt ccagcaatca cttgtacttc agggtaagct tctttgattt tgcttgctaa
     3181 tccttttgcg atctcttttc ggacttttgg atagctcatc gtgattcggt tatcacagta
     3241 aattgggctt ttgattccac ttgcccatgt aaaaggatta cttggattta aaaatactgc
     3301 ttcaatttct aataagtctt ttgcgatact ttgttcaaca ttcattttag gttagctcca
     3361 ttctgtttga atcgtttgat atgctttata aggattagtt gactgagtga ttggtcgacc
     3421 tataacgata aaagttgagc cgatcttttt tgcctgagaa ggtgtgacta ctcttgtctg
     3481 atctcctgcg actgttcctt ctggtcttat acccggagtt aagcaaacaa attcgtctcc
     3541 tgccatttct ttgatcgctt ctacttccca agcagaagaa accacaccat ctaatcctgc
     3601 ttttttggca cagctagcat aatggatcac acttttttct aaagaaactt cgattagttg
     3661 atcggcatgc atttcttctt cacttgtaga agtaagctga gtgatagcta gaagtagcgg
     3721 acgttttcca ccttctggag tcccctcttc taatcctcgc attgccgcct ccatcatacg
     3781 aataccgcca gcggcatgaa cacaggtgag atcaacacca agctttgcca atccccgcat
     3841 tgctttttcg accgtattcg gaatatcgtg aagtttcaga tctaaaaata cattatgacc
     3901 agcctctttt agataacgta cgatttcagg tccttcttgg tagaacaatt ccattccgat
     3961 tttcacaaac aatttttctt ctttcgggaa aaatcgaaga aagtcttcta cctcttgcct
     4021 agttgaaaaa tctaatgcaa taattggtcg ttggtctagt tgattcatcg ttcacgttcc
     4081 tctctcactt ctttgattaa tctttccagc gattcgatgc ctagttcgct cattcgcaca
     4141 gggagctctt taattagttt aggacagata tacggatcgg tgaaattcgc ggtccctata
     4201 gctacagcac ttgctccagc cataaacatc tcaagaacat catccactgt ctgcacgccg
     4261 cccatcccaa tgattggaag gctggatata cttgctactt ggtgaatcaa acgaatagcg
     4321 acaggcttga ttgctggtcc ggagagtcca cctgtttgat tggctaaaat cggttttctt
     4381 gtcttaaggt caatccgcat accaagaaga gtattgatca tcgtaaaccc atctgcccct
     4441 ccagcttcga ttgcctgagc gattggaacg atgtctgtta catttgggga caatttgaca
     4501 tagacaggaa cagaagaaac tttctttact gcttgtgtta attgaaaagc aacatcagaa
     4561 tctgttccaa aagcaattcc gccatgtttg acatttgggc aagaaatgtt cagctcgatt
     4621 gctttcacat ttggtgcttc gccaattttg ctacaaactt ctacatagtc ttcttcacaa
     4681 gcaccagcaa catttgcgat gatgggtaac tcattgtact cctctaattc tggaagaagt
     4741 ttatgcataa caacgtctag accaggattt tgcaaaccaa ttgcattcaa catgccagat
     4801 ggtgtttccg ccactcttgg cgtgggattg ccaaagcggg catttggagt cgttgccttg
     4861 accatgatcg atccaagctg attcaaatca tagtattttc cgtattcttt gccaaaaccg
     4921 aaacagccgc ttgccggcat gataggattt tttaattcta ggccaggaag tttgaccgct
     4981 aaaggattct cattcatata attacctctc ctattttaaa aatcggtcct tcgtcacaaa
     5041 ctttcacact ttttgttcct gtttcatctt ccggcgtatg acaaacgcaa gcatagcaag
     5101 cccctatccc acatgccatg cgggattcta atgataactg gacattttga tgcgaagaaa
     5161 acagctgttc cactgtcttc aataacccgt ttgaaccaca tgcaaaaaca gctgtaggtt
     5221 ccgtcttcgt tcctaacaat aaattaccga catttccgtg cataccgtat gttccatcgt
     5281 cagtagcgat tcttgtttct cctagacgat taaattcttt ttcataataa acgacttcat
     5341 gtgtggcaaa acctaaaaaa tgcgttggct taattccttt ttcgactaac tgttttgata
     5401 actcatatag aggagggaca ccgattcctc caccgattat aaatacttcg tctcctgtat
     5461 gaagattgga caaatcaaaa ccattgccta aaggacccat gacatctaaa tggtctccgg
     5521 cagaaagagt agagaagact ctagtcccct caccttccac ccgataaatg atacggcaag
     5581 tatttgtttc gtggtcgata tgattcaagc taatcggtcg gcgtaatagc aagtctgcac
     5641 gcggcacgag aatatgcaag aactgtcctg gttgctgcat ttcttttact agatcacctt
     5701 tcaatgtcat ttcaaaaatc tttggtgcca gctgtttttg ctgaacgatt tccatcattt
     5761 cttgtttcat ctgtcccctc ctgcaacggt ttttcgtctt tttgtcttaa catgtgctcg
     5821 ccgttaaata gggttagttg aaaaagcacg ggattccatc actcgaacga tcgcatctgc
     5881 tgtgtctaaa gaagtaaaca atggaatacc atgttcaact gcttctcttc ggatgatgaa
     5941 accgtcttta gaagcatttc cccgatcttt atcaatcgta ttgacaacca cttgtgtttt
     6001 accatctctt attaagtcga ctacattttt ttctgctgct tcctcagaaa ttttcgctac
     6061 tgtttcaacg accagaccat ttttttcgaa ataagcagct gtatgtttcg ttcctatcag
     6121 actatagcca atttctgtaa aacgtttagc taattctagt gcttcttctt ttgtttcgtc
     6181 cgcaatcgta aataatacgg ctccatattc aggcaagtgt aatccagaag cttcgaatgc
     6241 cttgtacaaa gctttgtcta attgtctgtc agatcccatt acttctccag tcgatttcat
     6301 ttcaggccct aagtaagtat caactttctg caatttcgta aaagaaaaga caggtgcttt
     6361 aacatgaact tcttttgttt ctggataaag tccgttttca taaccaagtg tctttagttt
     6421 ctctcccaaa atagctttcg tcgcaatttg tgccattgga attcctgtca ccttacttaa
     6481 gaatggaaca gtccgacttg ctcgaggatt gacttcgatc acataaacct cattttcatg
     6541 gatgacaaac tggatattca tcatcccgac acaattcaaa cctaatgcta agcggatcgt
     6601 gtaatcttcg atcgttttct tgatcgattc agataatgtt tgaggtggat acacagccat
     6661 tgaatcccct gaatggacac cagcacgctc aatatgctcc atgatccctg ggatgagtac
     6721 tgtttcaccg tcacaaatcg catccacttc gcattcacca ccaagcaagt aacggtccac
     6781 tagtactgga tgttctggag atgctttcac agcatgttcc atgtaatctt ctaaatctcg
     6841 ctggttttca acgatttcca tcgcacgtcc gcctaataca tagcttggac gaacaagaac
     6901 tggataacca attctcgaag cgataaccac ggcttcttct ttacttgtag cagtatcccc
     6961 taaaggttga ggaatatcca actctttcag cgcttgctcg aataaatcac gattttccgc
     7021 acgatccaag tcttcgatcg ttgtccctaa gatttttaca ccagcagcag tcaaaggttc
     7081 ggctaagttg attgctgtct gaccaccaaa ttgaacgatt actcctatcg gctgttctag
     7141 ctcgatcaca ttcatcacat cttcgaaggt caatggctca aaatataatt tatccgaaat
     7201 agaaaagtca gtcgaaactg tttcaggatt gctgttcatg atgattgctt cgtatcctgc
     7261 ctgctggatt gctttgacag aatgcacagt cgcatagtca aattcaaccc cttgtccgat
     7321 acggatagga ccagatccca gtactagaat tgagggcttt tctgatcgtg aactttcatt
     7381 ttcatattca taggaactat aaaaataagg tgtttttgat tcgaattccg ctgcacaagt
     7441 gtcaaccatc ttatatacag gaatcaaatc attttctttt ctcatctggc gaacggcttc
     7501 ttcgtttatt tcccacagct ccgccacttt tttgtctgta aaaccgtttt gtttcgctgt
     7561 tttcaatatc ttgtcatcca acggctgctg tttcaactgc tgttcgattt ctacgatatg
     7621 caacagttta tctaaaaaga ataaatcgat ttttgtcaaa tccgctaatt cttctatggt
     7681 gtaccctctt ctaatagctt cagctacata aaacaggcga tcatcttgtg ctcgaaccac
     7741 tttttggatt aggtcatcgt ccgtgatgtc tgccaactca ggaagttcga tatggtgtgt
     7801 accgatttct aaagaacgca cagctttcaa taaagactct tcgatattcc gaccgatagc
     7861 catcacttca ccagttgctt tcatctgcgt gcctaaaagc cgttctccgt tttcaaactt
     7921 atcaaacggc cagcgaggaa ttttagctac aacataatct aatgcaggtt caaattctgc
     7981 aaaagtcgtt cctgtaacag gatttttcat ttcgtctaat gttaatccaa gcgctatttt
     8041 agcagctagc ttagcgatcg gatagccagt cgccttactt gctaacgcag atgaacgaga
     8101 aacacgcgga ttgacttcaa tcacataata attaaaacta tgtggatcaa gagcgagttg
     8161 gacattacag cctccctcga tcttaagtgc tcgaataatc gaaagagaag catcacgaag
     8221 catttgatat tcatggtcag acaatgtttg actaggggca aatacgatag aatcacctgt
     8281 atggataccc accgggtcaa aattttccat attgcagaca acgattgcat tatcagccga
     8341 atctctcatc acttcatatt caatttcttt aaaacctgca atacttcgtt caatcaaaca
     8401 ttgggtagcg ggggaaagac ttaatccatt ttctgatacg atacgtaatt cttcttcatt
     8461 ttcacacata cctccaccag ttccgcctaa agtaaaggct ggacgaacga tgacaggata
     8521 gccgatttta tttgcaaaat ctacagcttc ttctactgta ttgacgattt cagactcggg
     8581 gattggctga ttcaattctt tcatcaactg tttgaataga tcacgatctt ctgcttgatc
     8641 gatcgcagaa agctttgttc ctagaagttc tatgttcaat tcttctaaaa tacctgatgc
     8701 tgccagctcc attgccatat tgaggcctgt ctgtccgcct aaagttggaa ggagagcatc
     8761 tggacgctct tttcgaagaa tccttgatac aaattcaagt gtgatcggtt cgatatatac
     8821 ttgatctgcc acttctttat ccgtcatgat cgtcgcagga ttagaattta ctaaaaccac
     8881 ttcatatcct tcttctttta aggcaaggca ggcttgtgtt cctgcgtagt caaattctgc
     8941 ggcttgacca atgatgatcg gaccagatcc aatcaccata attttcttga tatctgtacg
     9001 tttcggcatc tgtttactgc tcctttcctg cgtccatcat ttccataaat tcatcaaata
     9061 aatgtagtgc atcatgcgga ccaggggcag catctggatg aaactgcaca ctgaaagcgg
     9121 gataatctct gtgtttgact ccttctactg ttccgtcatt tacttctaca tgagttacga
     9181 tgagtttttc tggatcaatc gtggcttcat cgactgcata gccatgattt tgagaagtaa
     9241 aatcaattct tccggtcgct acttctcgta ccgggtgatt taatcctcga tgtccgaatt
     9301 tcattttata ggtatctgca ccgttggcta aagcaaataa ctggtgaccg agacaaatac
     9361 caaaaatcgg tacttttcct tggatttttt tgatcatttc gattgcttct ggcacatctt
     9421 ttggatcacc aggtccattc gtcagcatga ctccgtctgg tgatagcgct aaaatcgtct
     9481 cggcatctgt gttataggga agtactgtga ggttacagtt tcttttactc aattctcgta
     9541 aaatactatg tttcaagccg aagtcaatga caatgacttt ccgacctgtt cctggacttg
     9601 gataaggttt gttagttgag acttgctgca cttgattggt tgctagaacg gttgctttca
     9661 gctgatcaaa tgcatgttcg aaggaatctc cagcatcaac tatactagct ttcatcgttc
     9721 cgacttcacg gattttgcga gtaagggcgc gcgtatcgat acctgatatt ccaggaattc
     9781 ctttttgttt caaaaatgaa tctagcgtca tttggtttcg ccagtttgaa gctacacgtg
     9841 catgttcttt tactactact cctttgcatg ttggagaaat cgattcataa tcatctctat
     9901 ttaccccata attacccacc ataggatagg taaatgtaat gatttgaccg ttaaaacttt
     9961 gatcagtgat agtttcttga taaccagtca tacttgttgt aaaaacgatt tctccgaaga
    10021 cactagcatc tgcaccaaaa gcctttcctt cgaaaactgt tccatcttct aatataagca
    10081 aacgttccat acttttattc tcccttctgc cacacaagtt ttccgttgac aaaagtcatt
    10141 tgtgtttcgc cttttacttt ccagccgata aaaggtgtat tctccccttt tgataaaaag
    10201 tcttctttat cgatcgtgca agtttgtgta atatcaaaaa ctgctacatc agcgggggca
    10261 ccaaccgtta gcgttcctgc attcaaacca aaaatctcag ccggtttaac tgccaaccaa
    10321 ttgatcactt gttccaacgt gaatcgacca gtttctacaa aatgagtata gatcagttga
    10381 aacgctgttt cgcttcctac gataccaaat ggtgatttca tgaaactttg gcttttttct
    10441 tctaatccat ggggggcatg gtctgtagcg atgcaatcga tcgtaccgtc aagcaagcct
    10501 tcgatcaaag cttctctgtc ctcccgtcct cttagcggcg ggttcatttt ccaaaagccg
    10561 aaatcttcgg gaatatcttc gtcgatcaaa ataagatgat ggggtgaaac ttctgctgtt
    10621 acgtggattc ctgctttttt tgcgtctctg attacacgga cactttcttt agtagaaaca
    10681 tggcaaacat ggtaatgaac accagttgct tcagctagca acagatctct agcaatttga
    10741 gaagactcgg ttacgcttaa gatcccggga agaccaagtt cttctgcctt cttgccagcg
    10801 tgcataacgc cgccaaataa taaagattca tcttctgtat gggctactag ggctttattg
    10861 ttttttgcag cttctttcat agccagatac atcgtcccag ctgtttggac acctacaccg
    10921 tcatttgtga aagcaaaagc accttcttca atcagtgctt cttgatcaac taatttctca
    10981 cttcgcagat tttctgtgat tggcgcatac tgcaatacct tcacaactgc atcttttcta
    11041 atgatgtcat atacttgtct cagcttttct gccgtatcag gtacaggatt taaattcggc
    11101 atcgcgcata cagtagtgaa accgccacga gcagctgagc gagtcccagc ttcgatcgtc
    11161 tccttgtatg taaatcctgg ctctctcaaa tgaacatgga cgtccactaa accaggtgtg
    11221 atcaattgtc cctttgcatc aaacacttca tcaaattcgg cttctgagaa tcctgtaccg
    11281 attgctttga ttcgcccatc ttctatccaa atttctgctg gtgtcgtcat attttttcgt
    11341 gtattgatct gaccgttttt aatgagtgtt ttcatttttt catcctccta taattacgct
    11401 tttccattta gcactgcttc taagattgcc attctgacga atactccatt gctcatttgc
    11461 tgaacgatcc gcgactgtaa tccttccact aatgaatcag ctaattctac atcacggtta
    11521 actggtgctg ggtgcataat gattgcatgt ttttgcaact tcttcgcacg ctcaactgtt
    11581 aacccatgtt cctgatggta gccttctttt gagaaacttt cttttccatc atggcgttcg
    11641 tgttgcaccc gaagcatcat catgacatca acttgatcta gtagttcatc caatggcata
    11701 taatgtccgt acacttcgaa ttcatcgtcg taccattctc taggacctga gaagaatact
    11761 tgtgcgccta gacgttttaa catctgcata ttggatttag ctacgcgaga gtgagtgata
    11821 tcacctacga tggcaacttt cagaccttca aaatgaccaa attcttcata aatggtcatc
    11881 aaatcaagca agcattgggt tggatgctgt ccgcttccgt ctcctccatt gataatcgaa
    11941 cactggattg ttttactttg tatcagttcg tcataatagt tctcatcacc atgacggata
    12001 accgctacgt ctacgcctaa tgctgacatc gtcagtactg tatcgtatag tgtttcccct
    12061 ttttggacag agcttgtgct tgcttcaaat tcaatcactt ctagccctag ttttttctcc
    12121 gctacatcga agcttttatg tgtgcgagta ctattttcga aaaagaggtt tgtagcaaag
    12181 tactggcgct tttgcggagt ccaattagca ccttgcttga attcctgccc tctgcggatc
    12241 aagcccataa cttcttgatc agtaagtgcc tcaacggtca ataaatgctt taagctgata
    12301 cgttctgatt tgatgatcat aatgtttcct ccttagtttt cttcgcttcg tgaagtttct
    12361 ggtaagataa gatttaaaat gatgccaagt acagttgcta atgccattgc cgacaatgta
    12421 aatgtgccta cttcaaagac gagtccgcca attcctacta ctaagataac tgaagcaatc
    12481 aacagatttt tctttttatc aaaatcgatt ttgttctcga ttaaaatctt cattccactt
    12541 gcggcaatta ctccaaataa gataaaactg attcctgaga tgactggtcc agggatactt
    12601 aaaatcaaag cgcttaattt tcctacgaat cctaaaatga ctgcaaatac tgcagctcca
    12661 ccgatcacaa acacgctatg gacacgtgtg atagccagaa caccaatgtt ttcaccgtaa
    12721 cttgttacag gaggacctcc gacaaaggct gccacgattt gtgctaatcc atcacctgtc
    12781 aacgtcttat gaagacccgg ttcttcaaag aaattacgtt tagttagttt attcaatacc
    12841 ataagatggc cgatatgctc tgtcatcgtc acaaaagcga tgggtgccat tgttgtgatt
    12901 gctccaagat atagctttgg ttcatattgt acaaagggaa tctcaaagtt aggaacagca
    12961 aaccaggcag cgtctacgat tggcttagta tccacgattc caaacagcaa ggctacgatg
    13021 tatccgctaa taatacctag taaaatcgga atcaatccga gaaaacctct tagccacatg
    13081 ttgaagaaaa ttgttaatcc taatgtgatc agcgctacag caatatactt gaaatcatac
    13141 gtgccctgat tatacatagc atttgttgct gcatttgccg caagtcccaa cccgataacc
    13201 atgatgactg gaccgacgac gattggaggc aagattttat ccagccatgc tgaaccgatc
    13261 tttttgatga tcagcgcaac aatcaaatag actaatccag ttgtgactgc tccttgtgca
    13321 atcgctggat aaccatctgt tttcatcaaa agctgcatcg ctgcaatgaa agcgaagctg
    13381 cttcctaagt acgcaggtat ctttccttta gtagtaaata agtacaccaa tgtacctagt
    13441 cctgaactga ctagcgcaat acctggatcg atacctacta agatggggac taacacggtt
    13501 gctccgaaca tcgtgaacaa gtgttgtaaa cttaatccta cccaatgtcc tggggttggg
    13561 cgatcgtgga tatctaacac cacgtcatca ttatgaaatc cttttttctc cgacatgttt
    13621 ctctctcctc taatcttcct ctttcaaaat catgatgcga tcttgtccat caagctcttg
    13681 catctctact aaaatctctt ccgcccgaga tgttggaatg ttcttcccaa cataatctgc
    13741 acggattggc aattctcgat gcccacgatc gaccaggact gctaatgaaa tttttcttgg
    13801 tctgccaaaa tccattactg cgtccattgc tgctcgaatc gttcgtcctg tatacaaaac
    13861 atcatcaatc aaaataactt cttttccttc taaggaaact gggatgtcag aagaatgaag
    13921 ttccggttct tctggatttt cttttttgtc atctcggtat aaagtgatat ccagttctcc
    13981 tacaggaata tcgatatctt ctagctgctt caggcgttcg gcaattcttg atgcaatgta
    14041 gattcctcgt gttttgatac ctaccaatac gatatcttgg atactatggt ttctctcgat
    14101 aatctcataa gtaattcgag tcaatgctcg cttcatggtt acctgatcta ctacttcttt
    14161 tgcttgcatt ttcattcccc ctactttttt gcataaaaaa actcctgccc taagaggaca
    14221 ggaggaatgt ttagactgag cgtatactga tacactgata gctatactat gtcaatgagc
    14281 aatctactta tggcgcacca tacgtatcct tgctcccacc cttcttagcc tcacgggact
    14341 aaacttaaag gaattctatt aagttttatg ctttcgttgt taattactat accgttatct
    14401 aaattaaaat gcaatgtttt ttcttaattt ttctaaagtt ttttcaaaaa cttctggaag
    14461 aggtgcttca aagatcatct tttcgtttgt agtcgggtgc gtaaaaccta acatttgcgc
    14521 atggagaaac tgaccattgc ctttcaaagt tttcttcggt ccgtatactg gatctccagc
    14581 taacggataa ccgatatact tcatatgcac acggatctgg tgtgttcttc cggtttctag
    14641 ttttaattca accagagtaa atccttcgaa acgttccaat acagtaaaat gtgtgacagc
    14701 cgacttccca tcttctctta tcgcctgcat tttccggttt tccttcgaac ggccgattgg
    14761 cgcattgatg gttccttttt cgtgaggaat ctctccatgg actaaagcaa catatttgcg
    14821 caaagaggtc ttatctttta attgctgagc taatgattcg tgtgcctggt catttttggc
    14881 aaccattagc agtccggaag tatctttgtc gattcggtga acaatacctg gacgaataac
    14941 gccgttgatc gtagaaagat ccttgatatg gtacatcagc gcattgacca ttgtgccatg
    15001 cgtatgacct gctgaaggat gaacgaccat tccttgaggt ttgtttatca ccgctacatc
    15061 ttcatcttcg taaacgatcg tcaacgggat attttctggg accacatcta atgtttctgg
    15121 ttcggggatc aagacagtaa tctcgtctcc ttgttttact ttgtaatttg ctttgactgg
    15181 ctgtccattg acagaaaccg ctccattttt cagccacagc tgaatttgcg aacgactgta
    15241 atcggtgaat aaattagtca atactttatc gatcctacca gattcatggt gaatcgtcgt
    15301 tttaagttct gtcatttttt tctttgatcc ttttcatcta aaataatata aattaacata
    15361 caaatcactc cacatacaag tgtcacatct gctacgttaa aaatcggaaa gctcataaaa
    15421 tctgtctgga acatatctac tacatagcca agacgaatac ggtcgataaa attgccaatc
    15481 gcaccagcta gaatcaaact caatccaatc atgaaccagc gattaccttt ttcacgattt
    15541 ttaatcatca atgtgagaat cacaacgact gcaatgagtg tcactatagt aaagaaccac
    15601 atcttccctt ctagcatact ccatgcggct ccagtgtttc gaatatgatt cagtgacaaa
    15661 atacctggta taagattttt cgtctctcca agcgctagat tatcagtgat ccaccatttg
    15721 accaactgat ccactcctac tagcaaagcg ctgaatatcc aataaataat taacaaaaaa
    15781 tcaatccttt tctatttgtt tataaatatc acgaggtcgt acgatcccga gcagattacc
    15841 atcgggattc ccatctttag tgataagtac ggcttccaaa gtcccttgct cacgaaacat
    15901 cgcttcaacc tcgtaaatat gtgttttagc tggaacaaaa tgataatttg tgtactttcc
    15961 gttttggatg atcaaatcca acgctcgttt atttgttaaa tcaaccggac ctttttggct
    16021 ttcttttgct agccaaaacc cgatattacg taaagtaatc aatgctacaa attttccttt
    16081 attgtataac ggaaattgtg aatacctttt ttctgctact atctttaaca gttcaagtaa
    16141 cggaagatct tgttcaaaac ctgttacacg ttttgcaaat cgaggcagca cggtttcagg
    16201 ctgaatcagt tcttgttcga tcagctggat tcgcttgact gtccaatcat ttggctctgc
    16261 aatgacaaaa tcgactgcga tccgatcatg gacgatcgca ttccttaact gagcaagctg
    16321 taaaagatca tcttcgtatt ttctgatcat taattgtttt ctttgagcta ggcgtctgac
    16381 aagttcggta aatcccatat ttcgtgcatt tcccatctcg tctctcatcc atttttcgat
    16441 tcgattgaaa ctgattaaaa aaagatcaga gtttgccata attttcctcc ttgatcaaat
    16501 atgcccggtt ttttatatag aaaaagaacg caatcaacac aataactgca aaaaaactga
    16561 aaaataaatt ttgtaggaaa acggccccca acccagttgc tagaaataaa aacggataga
    16621 tttgaagaat caagtaattc attgtgatca cataagcagg ctttgcttct ttcactgtat
    16681 aaacggggct ttttagccaa taaaaggtga cctgcatcgt aaagggcact tccagatcaa
    16741 gcgttatctt ttgttcatga ctgagaacac tgcgtttttc attgttgatt cttagctgaa
    16801 tcgagctacc cataccgtaa aaaccggttt ttcttataaa tgtcgttttc atcataccct
    16861 cctattatgc tttagtatag ctcaaaatac aataaagaaa aagaatgatc ctagtgtaaa
    16921 caaaattaat tccctatcgt ctaaaaaaag aagctgtagt caaaatacag ctccttcgat
    16981 ggtagattat aatcaagctt aaaacaatcc caacacttct ccgtcatttg tcacgtccat
    17041 attcaatgca gcaggttttt taggcaaacc aggcatcgtc ataacatctc cagtcaaggc
    17101 tactaaaaat cctgccccta attttgggat gatttcgcgg atcgtgatgg tgaaatcttc
    17161 cggtgcacct agcagtgaag gatcatcaga aaatgaatac tgtgtttttg ccatacaaat
    17221 cggcagtttg tcccatccat tcttcgtaaa ctcttctatt tgtttttgcg cttttttgct
    17281 gaaaacaaca ccatttcctc cgtaaatttt cttgacgatt gtttctgtct tttcttgtat
    17341 cgtttcttct aggcggtata atggcttgta attagcttct tttctatcaa tcaatcgtac
    17401 tacagctttt gctaaatcaa cgccgccttc tgctccatct gcccatacac tcgctctctt
    17461 ggcaagaatc ccctgatttt cacacaagtg ctccaacagt gtgagttcat tgtctgtatc
    17521 tgttacgaat tcattgattg cgacgatcac aggtagctga tattgttcca tattacgtat
    17581 atggcgcttt aaatttgcaa aacctacttt caaagcatca agattctcat ttttaagttc
    17641 atcttttttc attccgccat gcattttcaa tgcacggaca gtggcgacaa tcaccacagc
    17701 atccggcgct tttttcaagt taggtacttt gatatctaaa aatttctctc cgccaagatc
    17761 tgcaccaaat cctgcctctg tgacaacgta atctgctaat ctcaatgctg tcttggtagc
    17821 taaaatacta ttgcagccat gagcgatatt ggcaaacggt cccccgtgga caaaagctgg
    17881 tgttccgtaa attgtttgta caagattcgg cttgattgca tctttcagca gtaatgccag
    17941 agcgccttct gctttcaagt ctccagcagt cacaggctga cggtcaaatg tatagccgac
    18001 aacgatcctt gcaagacgag cctttaaatc ttcaaggtct gccgcaagac acaagatagc
    18061 catgatttcg ctggcaactg tgatatcaaa cccatcttct cttggaacac cttggattgg
    18121 cccacccaag ccaacaatta ctttacgcag ttcacgatca ttgagatcga ctacccgttt
    18181 ccaaatcact cggcgggcat cgatgttcaa ttcatttcct tgatgaatat gattatctaa
    18241 aagagcagat aatgcattat tagctgttgt gatagcatgc atgtcaccag taaaatgcaa
    18301 gttgatatct tccataggca atacctgtgc atatcctccg cctgcagcac cacctttgat
    18361 tcccatcaca ggaccaagtg agggttctcg caatgcaata acagattttt tattgatttt
    18421 attgagcgcg tctcctaacc ctacagtgat cgttgacttt ccttcgccag ctggtgttgg
    18481 attgatggaa gtaactaaga tcaaatgccc ctcagcgtta tcctttgatc gattgattcc
    18541 agaaaaattg attttcgcct tatatttccc atacagttcc aaatcgtctt ccttaagatc
    18601 taatttacta gccacttcaa caatcggttc tagctctgtt tcttgtgaaa tttgcagatc
    18661 attcttcatt tgattacccc ttttcacgaa ctttattcaa caaaatatct tctttgttaa
    18721 gatatgccaa ttataccttt ttttattcag aaaaaaaaca taaaattaca ggtttttaat
    18781 ttatttgacg tacttataaa tactctttat aatgaaggct atgatcagac tttagaaagg
    18841 tcgtgagtgc tttgaccaca ggaattgtaa aatggtttga caacaaaaaa ggatacggct
    18901 ttatcagtta tgatgacaca gaagaaattt ttgtacattt tactgcgatt gaagaagagg
    18961 gattcaaaac tttggaagaa aatcaagtgg tcgaatttga gatcatcgaa gggaatcgag
    19021 gaacacaagc tgcccatgtc aagaaaggca acgttcagac taccgatact agtatgcatg
    19081 aatagataaa caaatagagt gagacgctaa acgggatgaa ccgtacgtct cactcttttc
    19141 ttttcctgta aaaattcgtt tttttaggtt ctgattttta aaattagctt tttctttttt
    19201 tcgtataagg ataaggaatt gattctgatt tgggtccgtt tttttcaaaa tgatcaaaaa
    19261 ggactacttg atcttttttt cgcatcatga aaacagatgg ggctttctca tcttgcaaca
    19321 tcatttgcac cccagtatta gttggcgtca aagatcgaat ctgtccgaca gatatttctc
    19381 ggtctttcca aaaagcagca taacgtataa tcacagagtt tgattttaaa ataaaagaac
    19441 gccgcaaacc tagaaataga aaaacaagaa aaatacctaa aacaaaattg cttttccaat
    19501 aaggacctgt gttttctaaa gaaagaatca gactaaaaaa cagaatgatc aaggtcaatg
    19561 accaatagat gatcgtatgt gccagttcag gctgccatcg aatatttttt ttcattctct
    19621 aacctctcac cgattcagta atgatataat cttaccataa cattagtttg aacaaaaagg
    19681 agaatctctt tttatgttaa aagtatacat tgatgcctct acaaaaggca accctggtcc
    19741 tagtggaggt ggaatcttga ttgtctatca aggtaaacaa gaacagctat ctatcccgct
    19801 ttctataggg acaaaccatc aagcagagtt cgaagtcttt ttaaaaactt tagaatttct
    19861 aaagaaaaac gacttacaga atgaaacgat tttctgtttt tcagacagca aaacactagt
    19921 ttctacggtc gacaaaaacg caacgaagaa cgagctcttc cttccctacc ttcaaagaat
    19981 ccaagaactt ctatccgaat tttctttatt gatcctgcaa tggttgcccg aaaacaaaaa
    20041 taaaggagca gataatcttg cacgtcaggc tctccataaa caattaaaag aaaaaaagac
    20101 tctttaaatt aaaaacttta aggagtcttt ttatagtttc tcatttaata taaaagataa
    20161 ttgtgatcaa acgtaatttc caattggtaa tctccgattt tttcttctat ttgactacgt
    20221 aagattcttt ctagttctgt atcaacaaac tggaatttct cagggaccac tacatcaaat
    20281 tgcagcgttt ttccttgatg aattactcta aaatcatgaa tattaagccc tgtacctgtt
    20341 tcaagaagaa tttgctttaa ctgccgcaag atattatagt atttttcgtt atcaacaggc
    20401 attggatcca agtgacagac aagttccaca tccaaagact ttttaaagtc tttttctatc
    20461 agatcaataa tcttatgagc cacattcaaa ttcattgatt catctacttc gatgtggact
    20521 gatgcaaagc gtttattggg tccatagtta tgcaccaata aatcatgata gccaagtata
    20581 tcatcgcaag catttaaatg ctcttccatt tcttcaatct ctgctggcgt tgggcgactt
    20641 cctaatagtt cgtatacaaa atttcgaagc atcgtcaatc cactataaag gatatataat
    20701 gctaaagcaa aacctatata tccatcaata cgccatccag ttacccattc gattgctgct
    20761 gaaagcaata cagccagtgt agtaaagaca tcattataac tatctgttgc tgtagctctc
    20821 aatgtttcag aatcaatgga ttgcgcaata acctgataca ttttgccttg tgcaaatttc
    20881 aaaaagatgg aaatgattag gacaaaaaag acgatgggtg ttaaagagac attttctgga
    20941 tggatgattt tttcagcaga agactctaaa aattgaaatc ctacataagt aatgatgatc
    21001 gaaacaaata acccactgat atattcgaag cgttcgtgtc cataaggatg ttcctgatct
    21061 gctggctttg cagcaatttt aaatccgatc aaagtcaata tggatgaagc agtatctgat
    21121 agactgttca ctgcatcagc cataatggag acacttcctg aaaaaagccc gatcattagc
    21181 ttagagacaa acaagatcag attcgtaacc aatcctaaga tacccgctag tactcctttt
    21241 tttgtccgct gttgcggtat ttgtttcttt ttttcttctt gtttcttagc caagtttttt
    21301 accccttcta gtttgcttgt tgctcaggta aaaagatgga gaggacgatt gttttcctct
    21361 cctctcttcc tttttctatc tatcgtgcgt cctattacta ttaaaagatg gtcattattc
    21421 tggtttcaac ggtgttgctg caaataacgc ttttgctagt aatggtgtta tgattcccgc
    21481 acctattgct tctggtatcc cattgattgc tgcaacccct gctaaggttt taaataaaag
    21541 agcagagtct acaccatagg catctgccgt tgcacctgta taaaataatc ccatgaatcc
    21601 taacactaag actgtattga ccaatgaacc cagtacccct gcaaaggctg agctgatcgt
    21661 tattgattta tttttttgat aaatccagtg gaaaaccaag cctgctacta agccaacaag
    21721 tactctggga actaccgaga taatcggatt cgtgaacact aatgtatcaa atggcgttgt
    21781 tggcatggca taggcacgaa caattgtagc gattccccaa aacaagccaa tcaccatgcc
    21841 atcttttggg cctaatacta ctgcagcaat aattactgtg atatggataa ttgttaaact
    21901 aatgaatcct aatggaataa accccagcca aggaaccatc gcttgtacga tgatgattgc
    21961 taacaagatc gcacgtaaga ctagtcgaaa ggtcttattt ctactattca ttttttcacc
    22021 cctttttatt tatactaatc gtaaaaattt ctgtcacttt cgtcaactaa agaccatccg
    22081 aatccgacca tttgattaga tgcgccatcc aattgaaaaa agtatgaggg caagacttgt
    22141 ttgtcttcgc ccccataatc atgtttcgtt caatgtttga acttttgttt ttctgtcaaa
    22201 cgtaaacgcc ctattgttgc gcaacccatt ctttcgcagc tttaagtgca tctggaatac
    22261 cagcaggatt tttcccgcca gcttgtgcca tgtctggacg tccaccaccg ccaccgccta
    22321 ctttcggtgc gattgcttta atcaagtcgc cagcttttag tccagcttca tttgattctt
    22381 tcgtcattgc cgctagcaga ctgacttttc cttcttgttc gtttgctaaa acaagaatat
    22441 ctgaaatatt tttttgtttc cattggtcag ctaattgacg cagctgattc atatctttca
    22501 cttttacttg tgctgcaatg attgtttttc cattgatcgt ttctggatct ttgaatacat
    22561 caccagcttg ttgattcgct aacttgctag ctaattgttc attttccttt tgtagctctc
    22621 ttacttgctg ttgcaattgt tccgcttttg aaacaacttc tttcaattga ggtgatttaa
    22681 caattgttgc tacttgtttt agttgttttt cttcttcttc aagtagttcg tacgcttctt
    22741 tacttgttac agcctcgatt cgtcgcacgc ctgcaccaat tcctgattca gaaacgattt
    22801 tgaagattcc gatgttttct gtatttgcta catgtgtgcc tccgcacagt tcgattgacc
    22861 agccgccaat atttactact cgaacgtcat gtccgtattt ttcaccaaac aaagccattg
    22921 cacccatgtt tttggctgta tcgatatctg tttcaattgt ttcaactggg atagcttccc
    22981 agattttttc gttgacgatt ctttccattt cagctaattc atctgaagtg atttgaccaa
    23041 agtgggtaaa gtcgaatcgt aaatgtccag gagcgactaa agaaccagct tgatttgcat
    23101 gctcgccaag tacttctttc aatgccttgt gcagtagatg ggttgctgta tggtttttga
    23161 tgatccgatt gcgcatcgat tgatcgatca atagatgata ggtttgtcct tcactcattg
    23221 gtgcttttac ttctacggtg tgcataaatt gaccattagg cgctttttga acatctgtaa
    23281 caactgctac gatttcgcct acttcattca tgatccatcc ttgatccgct acttgcccac
    23341 ccatttctgc atagaaaggt gtttgatcaa agatcatttg agcttcacct tctgcgactt
    23401 cattcaaaag agactcacct ttaacgatga ccaataattg actatctgat tcttgttctg
    23461 tgtatccaat gaatttactt tctactttga tatctgtcaa taaagcagat tgtaccccca
    23521 ttgatttttc agtactgcgg gcagagcgag cacgttcgcg ttgtgcatcc atttcttttt
    23581 caaaaccagc atgatcaact ttcagtcctt catcttctgc cacctcttcc gttaattcta
    23641 ccgggaagcc atatgtgtcg tatagtttga agatgtcttt tcctgctaga gtcgtcccgt
    23701 tttcgttttt tacttcttgg atcacttgat ttaagatttc caaaccttca ttgattgttt
    23761 cattgaaacg ttcttcttct gtacggataa ctttttcaat aaattctttt tgttgaagta
    23821 cttcaggata ataacttacc atgatttccc caacaacagg gactaaacga tataagaatg
    23881 cttgttcaat acctaatttt ttcccatgca tgacagcacg acgaagcaaa cggcgtaaga
    23941 cataccctct cccttcattc gatggcaatg caccgtcgcc aatagcaaat gaaagggcgc
    24001 gaatatgatc tgcgattact ttgtaagaaa tatctgttac tgggttttca ccatatttta
    24061 cttgtttgct tagcttttct acggcgtgga taataggcat aaacaagtct gtctcaaagt
    24121 tcgttgacgc atcttgaacg attgagacca tgcgttccaa tcccatcccc gtatcaatgt
    24181 ttttatgagg aagtggttca aatgtgttat caggcttatg gttgaattct gaaaatacta
    24241 agttccagat ttctaaataa cgttcatttt ctcctcctgg atagttttca ggatcgtctt
    24301 ctgctaaatc gttataagct tctccacggt catagaaaat ttccgtatcc ggaccacatg
    24361 ggcctgcacc gatatcccag aagttgtctt ctacatcaat aatgtgatct agtggcaggc
    24421 caacttcttc atgccagatg cgttttgctt ctgtatcttt tggataaact gttacataaa
    24481 gtttttctgg atcgaatgcc atccattttg gatcagtcaa aaattcccat gcccagtgga
    24541 tggcttcatt tttgaaatag tcaccaatcg aaaaattacc cagcatctca aacatcgtat
    24601 ggtgccgtgc tgttttaccg acattttcga tatcatttgt tcgaatagat ttttgggcat
    24661 ttgtgattct tggattttct ggcacaactg aaccatcaaa atattttttc aatgttgcaa
    24721 caccagagtt gatccacaat aaggttggat cgttcacggg gatcaaagac gcactaggtt
    24781 caatcgtatg tcctttagat tggaagaaat caagaaacat ttgtcgaact tgtgcactac
    24841 ttaattgttt catgtcatta cctgctttct ataaattaaa tacaaaaaaa caccatcaca
    24901 gccaaggacg aaaactcgcg gtaccacctt gattgcaatg atgtgtaatc attacctctt
    24961 aaactcgata acgctgagct gcgtcggtat ttctaccaaa atagaaaaag ggagcaattt
    25021 gattagtgac tattcttttt tcagccaaga aagaattttc tgtgagtctt aaaaaacaaa
    25081 tcatatcctt ttcgtactta attagtatac gcattctatt gatcactgtc aatatctcaa
    25141 tttttatttt catttccttt tggtcatact ccacgatttt tggtacgata agaataaagg
    25201 aatcaataca tctctgctat tcatgacaag gaggaatatg atgaaaaaaa tagttggagc
    25261 ggatgaatgg atacgcgcag ctagctgctt tttgagatat caagtttttg tattagaaca
    25321 agggattcct gcagaactag aattcgacgg aaaagatatc ccgcaacaaa cctattatct
    25381 atttcttgat caaaaaagac cagtagctac tttgcgttat gaaaagaaaa cacctacttg
    25441 cttcaagccg gaacgatttt gcgtagcaaa agaataccga ggaaaagggt taggcggtca
    25501 gttgcttgaa gctgctgaaa aacgggcggt ttcagaaggt tgtcagacta gttatgtagt
    25561 agctgaaatg acggctgtag atttttatga aaaacaaggg tatcatactt gcacagaacc
    25621 ttttattgaa gatgaagtac tttgtatcgg aatgaaaaaa agtctagctt aaaaacaaga
    25681 gattgtgaca cgccttttgt cacaacctct tgttttttat ttatgtgaat ttttcttatt
    25741 tttacgagca gtacggcttt gctgtctgcg ttcgattttg cgttcttttt tatttttttc
    25801 tgcaattgcc caatcgattt ttttcttata accaggcttg atctttttct ttttcttctt
    25861 cacaagacca atcagcgtgg gatctaatac atcttttgat ttttctcgtt tggcacgtct
    25921 attacgatcg tatgttttga cgatttcccc gtttttgatt tcttttggtt caaatgagac
    25981 gcccaatttt tctatcgcat caatggcttg ctcatcattt ggcgaatata acgtaatggc
    26041 cgttcctttt aagccattac gtccagtacg tccgacacga tggataaaga agtctagatc
    26101 ttctggaatt tctgcattaa taacatgaga gacaccttcg atatcgatcc ctctagcagc
    26161 taaatcagtc gctacaacat attgatactc cagattctgt acttgtcgca tcactcgttt
    26221 tctctctctt ggggtgatgt ctccatgaat ctttgctact ttcaagcctt ggtttttcaa
    26281 gtaatcggca atttcatcca catgctgttt tgtattggca aatacgattg ctaaataagg
    26341 atgaccaatt gtcagcagtt gataaatcat ttgattctca tctttacctt ttgttgaaat
    26401 cagccaattt tcaatgtctt cagaaataac tgcttttggt ttgatttctt caatgattgg
    26461 attttccatg tattttcgta agaatggacg aagtttttct ggaatagtgg cagaaaaaac
    26521 taaaaactgc agcttttctg gtaatcgact tgcaatttgg tctacttcat ttaaaaaacc
    26581 catatccaat gtcatatccg cttcatcgac aacaaatgca aatgcggtgt gaatcttcag
    26641 cgcttgttca ttcatcatgt ctaatattct accaggcgtg cctactacaa cctgtggctg
    26701 ttggtgatgc agacgattta attgacgctg tttgtctgta ccgccgacaa aattcgagac
    26761 acggatctcc ggtgtagaaa atttagcgat ttgtgtagct gcttcataga tctgtgcagc
    26821 tagttcccta cttggagctg taataacaac ttgtacttcc tctttttctg cattgatttt
    26881 ttcaaacaaa ggcaacaaaa acgtatgtgt ttttcctgta ccagtttgag attgcccaat
    26941 gatatttttt ccttttgcaa ttaaaggaat caaacgttcc tggacctctg tgggctgttt
    27001 gaagcccttt gcggttaacg cttcattgat aaacggtttg aagcggaata tatcaaaatt
    27061 attcattcgt gcacctcttc tctttaaatt atcacgactt tggcattata acacagacaa
    27121 agcgtttttg ctcagctaat ttcgagaatc atcatccttt gtttggccaa tcgtgctaac
    27181 agtatatgtg tgactagctt tttcataaaa cagaatccgt ttttttctca aaaatgatag
    27241 caagatattt aaaataaaaa taccttgtag taacaagaca ccgagagaaa tgaatactgc
    27301 actcatctgc aacaccgtat tcgttgtcga attcatgatt tgctgaagca actgccccaa
    27361 ccagcttaaa ccataaaaaa gaaagtacag atacccgtag cggatcatca atgcttttaa
    27421 agaaattcgt tcgcggtctt cttccaccaa acggatacgc acaatttttt tgccaagtgt
    27481 ccatccattg gttataaacg gtacaatcat aaagtatacc cctacttcta ataaaagcca
    27541 ccagatatga gaagtaactg cccctgaatc gaacgcaatt ttaaagaaaa tcgccgctac
    27601 caaattaata agagataaaa atgtccagtc gatcaaataa gcgaccaagc gtcgagtcaa
    27661 tgagacagtc tttccttttt cataagaaag ttcatccatt cgtcttcttg taggaagcat
    27721 aaatgtaaat aacggcgtaa cgacaaaacc aatgattcca cccaatgtat ttgtcactaa
    27781 atcattcaca tcaaataagc ggtatggtct tgggtagata aaataaagtc cacttagctg
    27841 cgtcaattca aaaaatagag aaaggcagaa actagcaatc atcgttttca taaaagaaag
    27901 ccggaaataa tatcttaaat aaatgccaaa cggtatgagt aataaaacat taaaagctgg
    27961 ttccaaaaat acactctgct tcattgccgg caggtaggta ctaggttcag acaagaccaa
    28021 taccgtgttg tctctgaaat gttgccatga agcaaataaa tgcagctcca tctttggccc
    28081 tgtcatttgg gcaaccgtct cctttgccgg aagtggtaag atcaccaaaa aatacgcaca
    28141 caataaataa aaaacgaaag aatacaaaat aactgccctt gttactagaa atgttccata
    28201 ctttcgatat tcataaataa aaaaaacaga tgagatcgct aaggctaaaa atggaaaaac
    28261 aatcagcgca aaacgaatcg gttcgatata acttgccata tgactcctcc ttgattcttt
    28321 gtatctctct tatcttagca gtcctttgct gtttcaagca agtaacgagg ctattatttc
    28381 tcatttcttt caaagtaaag taagataaac acaaaggggg tgtcgagatg ctgaatatgt
    28441 actttgtttt tggcgtacct atttttttac tgttccttta tgctacgatc gcttatgtaa
    28501 gaaaaagaac tacaattcat tatttaggat ttattctcct gattatttcg ggtttcatgc
    28561 tagtcttcaa tcttcagact tggcagcaag cacttcttga aatggataaa atgactccac
    28621 atgctttgtc taaagtgctt ggctaccctg tctatctgat ttggcttccc attttcattt
    28681 ctggttgctt ggttttatta aatatttatc gcggcgtacg ccgaatagtt cagttacgca
    28741 aatcaaagta aaagacagaa atcggttgag cccgatttct gtcttttact ttgctatttc
    28801 atcgtagaca aaacgacatt tacgtgatca aaattaacga gtacttttga catttcttcc
    28861 acgtactcct catttaaata aaatattttg tttggcagag aagtgcagtt ctaataaaat
    28921 tcgaatgttt tagctatcta cgttttaaat agagataaat cgggatacca gcaagtgtca
    28981 atactatccc catcgaagct aaaaaggtct gagtgataag cgtgcttgat acgataaaag
    29041 tccctccaat gattgctact agtggaataa acggatacat tggaactttg tatggtcgaa
    29101 acaaatcagg ttctttttta cgaagaagaa tgacaccaac aaagaccatc gtataaaaaa
    29161 tccaaatgac aaagatcagc atatccgtta gtgtatcaaa accaccgatc atcatcatgc
    29221 caatagcgat gactagctct aagatacctg cggctacagg aactttagtt ttatcatgaa
    29281 gtttagcaaa gagcttgcta aaaggcaggt tgttttcttt tgccataaca taagggagac
    29341 gcattccagt aagggtatag ccattgatgg ttccataaac agaaatcaag ataccaactg
    29401 tgaccagtct tccaccgaag ccgccaaaaa tcatttttgc aacgtcactt gccgcattgc
    29461 tgtttcctgc gactccgtcg atagatgcgg ttcttaagaa caccgcattt actaataaat
    29521 aaacgatcat gattccgatg attcctaaag aaattgcttt tggcaaatct ttcgccggct
    29581 ttttcaattc tcccgaaata tttcctacgt gtatccaacc gtcgtatgcg aacatcgttg
    29641 ctagcaagcc cgctcccaag gctgagaaaa atgaaagatt ttctcctgct tggatcggaa
    29701 acagttggaa gtctactcct tcttgtcgga acaaaccgaa aatgacgatc acaaacaaag
    29761 gaataagctt gcagacaagc gtaatcgact gaaaagcccc tccagcttta gaacctaaaa
    29821 aattgatcaa caggatcgat acagcagctg taacagctac gggaacaatc attgactggg
    29881 aaagaccaaa tagattgacg aactgtgtac cgaaaatgat cgacaaggct gctacatttg
    29941 ctggaaaata aatcacgact tgcgcccagc ccaataaaaa agctgctgta tttccgtaaa
    30001 tccgttcgat atatttaatc atccctcctg tttctggaat agcagctgcc agttcagctc
    30061 ctgttagtcc tgcacagaca gaaatcatac caccgagaaa ccaagaaaac atatgcaaac
    30121 tggcggatcc tgtaacttct gctacgcttg cggctttaaa aaatacccct gcaccgatca
    30181 ctgtgcccat aacagtcgat aaagcagtaa aaaatcccat cgtacgtttt aattcatttt
    30241 ctatttttac ttcttttact ggcgtggctt gatattcttc catcccttgt cccctttcat
    30301 accatagcca atcccaaaag tataaaaaac tttttggatg tggttcttgt tttataccgt
    30361 ctctaccaat ttttctttca gtttttccaa catatccttt gtcatcacat ctaagtcgta
    30421 tttcggcgaa aagccccatt cctcttgcgc acaagaaaca tctagtgaat ttggccaaga
    30481 ttctgctatt gactgacgta caggatccac atcataatcc atttcaaaat ctggtatgat
    30541 tttttgaata gatgctttga tctcttccgg gtcaaaagac atcgccgata tattgaaggc
    30601 atttcgatga accaatcgat caggatctgc attcatgagt tttataatgg catcgatcgc
    30661 atctggcata tacatcatat ccattgatgt accttgatca atgaaactag tgtactttcc
    30721 ttctttgatt gctgaataat aaatatcgac tgcgtagtct gtcgtaccgc ctcctggcaa
    30781 ggttgcataa gaaatcaatc cagggaaacg gacaccacga gtatctacgc catatttcac
    30841 ataataataa tcacatagta gttctccagc taccttcgtt accccataca tggttgtagg
    30901 acgctgaaga gtatcttgtg gggtatgatc ttttggagta tttggaccaa acgcgccgat
    30961 tgaacttggc gtaaaaaatt tcagctggaa ttctctagcg acttccaatg cattgaccag
    31021 cccagtcacg ttcaaattcc aggctaattg tggttttgct tctgcaacag ctgacaaaag
    31081 agcagccaaa tgaatcaatg tgtccacttg atattgttct gctatgctgc gcattttttc
    31141 gtaatccatt acatctagga tctcaaagat atcgtttttc tcaatgactt caggcatgcg
    31201 tatatctgtc gcaatgacat tttcactgcc tagttcttga cgtagccgtg tgatcaactc
    31261 tgaaccaatt tgtcctaaac atcctgtcac caatactttt ttcatgatga tcctccctga
    31321 tcttttttac tactatcttc agatgattaa caatatatgc gtgaacatgt tctctaattt
    31381 taaatagacg aaaaaactaa atttagttaa ataatttcca tttcttttcc tattttttga
    31441 taaactgcta ctgcttcatc aagcatttcc ctcgtatgtt ccgcagtcgg catatttctg
    31501 atcctgcctg tcccaagagg cacagttgga taaacgattg gtttagcata aatcccatgt
    31561 tcgatcagct tcttagagaa agtctgagtc actttttcgt ctcccaaaat gactggagta
    31621 ataggtgttt cagacatacc gatgttatag cctacttttt tcaattcttc tttaaaataa
    31681 ttagcatttt cccaaacttt ttcgacaagt tccggatgtt cttgcatcaa agtaatcgaa
    31741 gccaatgcag ctgcagctgc acctggagtt agcgaagtag aaaataggaa tggccgactt
    31801 ctagctttca accagtcgat tagtgttttc gatccagcta cataaccccc aacaacacct
    31861 atagctttcg ataacgtgcc catttgcata tcgattttgt cgcttaatcc aaaatgcttg
    31921 acggttcctg caccttttcc agttacgcct gagccgtgcg catcatcgac gtaggtgatc
    31981 agtccatatt tttcaacaat cggaataatt tccggcaatc gtgcaatgtc tccatccatg
    32041 gagaaaacac catctgtgat atacatgatt tttttatatt tcttactttc tatcgcttcc
    32101 tttgcttttt tctcaaggtc tttcatatct tgatgtttaa ttcggatgat ttttgctccg
    32161 gataagcggc aaccgtcaat aatagatgca tggtttaatt catccgataa gatagcatct
    32221 tcttttgtca ttactgcaga gatagcgccc atattgcagt tgaatccaga ttgaaaggcg
    32281 attgctgctt ctgtcccttt gaattctgcg attttttctt ctaattgctg atggattttc
    32341 agcgaaccat tgatcgttcg gactgctcct gctcctacac cataagtttc ggttgcttca
    32401 atacatgctt ttttcaattc ttcgcgattg gcaaatccaa gataattgtt ggatgctaga
    32461 ttgatcatct tttttccgtc tacgatgata caagcaccat tttcactttc tagtatgtcg
    32521 atcgtattgt ataacccctt ttctttcagt tgatccaatt ctttctctaa atacattgtt
    32581 agttctttgg aagacattgt ctccacctcc atattcatct gtcttgcaga acataccaaa
    32641 catatatcgt gtcattcatc tacaaagcaa gtatgctata tttttgataa cgcttacact
    32701 gattatgaga attatttaac cacatttttt atttacagta tctttttact ttcaaatgac
    32761 ttatatagta tgaacaatta ccttttagat aatgatctat tttactctac ctgggcagat
    32821 aaatacaaca caaccattga tagaagccct ttcgttaaaa tcaattgtat tctgaatatt
    32881 taatttattt attgcataga ccaataaaaa tacataaaat ttccatcttc gtttatcagc
    32941 aatttttaat tttactctct gaatatttct taaaagtttt acttgttgaa ttcgaaaaaa
    33001 ggactgtgac aaaagtcttg tcacagtcct attcttccga ata
//
LOCUS       DAZKKZ010000032        32765 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.032, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000032 DAZKKZ010000000
VERSION     DAZKKZ010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 32765)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32765)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32765
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.032"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(29..1261)
                     /locus_tag="ACG8LA_001550"
     CDS             complement(29..1261)
                     /locus_tag="ACG8LA_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HFQ0203855.1"
                     /translation="MLSDFNELLKKYARLIAETGVATEKGHTVVLQISVEQAPLARLI
                     TQEAYKLGAAEVIVQWTDDQIQREFLLHAATDRIENVPQSKIDQADEWLEKGASRISV
                     VSADPDAFAGVDSHRVASYQSANGKALMNLRKATQANKVSWTVVAAAGKQWAAKVFPE
                     LPEEKQVEALWDQIFKTTRVYEEDPVLAWKKHDEKLAKKAEELNREQFSALHYTAPGT
                     DIIIGLPKNHLWEGAGSYNARGEKFMANMPTEEVFTAPDSHRVDGYISSTKPLSYAGT
                     IISGMKFTFKDGKVVDFSAEQGEDVLAKLLDTDEGARRLGEVALVPDPSPISQSGIIF
                     FNTLFDENASNHLALGSAYAFSVKGGTEMSDEELAEAGLNRSQTHVDFMVGSDKMDID
                     GIREDGSTVPIFRNGDWA"
     gene            1516..2085
                     /locus_tag="ACG8LA_001551"
     CDS             1516..2085
                     /locus_tag="ACG8LA_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFQ0203856.1"
                     /translation="MARKKTITREQILAAAYEVAATDGFTRFTARNIANKMNCSTQPI
                     YLEFKNMDDLRQALFEQIYDHLQYEVFTVEHTGNTIIDLAFNYIHFARREKKLYRSLY
                     LEEYGGGKEMQNFSYTYFVNTVKRDPAYVNLSEEQIESLYNGTWIIATGIAALMSSSI
                     IHPTDEQIEKMIQDSIDAILKFKEPIEID"
     gene            complement(2263..2703)
                     /locus_tag="ACG8LA_001552"
     CDS             complement(2263..2703)
                     /locus_tag="ACG8LA_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HFQ0203857.1"
                     /translation="MALAKIVYASMTGNTEEIADIVAEAFENLDIEVEINECTQVDAD
                     EFEEADICVVATYTYDDGDLPDEIVDFYEDLQELDLLGKIYGVCGSGDTFYDEFCKSV
                     DDFDAAFAKTGASKGAENVKVDLNAEEEDIENLEAFAKELVAKI"
     gene            2861..3625
                     /gene="map"
                     /locus_tag="ACG8LA_001553"
     CDS             2861..3625
                     /gene="map"
                     /locus_tag="ACG8LA_001553"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008377375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HFQ0203858.1"
                     /translation="MITLKSAREIEMMAESGALLADVHKNLRDFIKPGITSWDIEVFV
                     RNYIESHGGIAAQIGFEGYEYATCISINDEICHGFPRKKPLKNGDLVKVDMCIDLKGG
                     ISDSCWAYVVGESTPEIDRLMEVTKKALYIGIEQAQVGNRIGDIGHAIQTYVEGENLA
                     IVRDFIGHGVGPTIHEEPAVPHYGEAGKGLRLKEGMVITIEPMVNTGTWKMKMDPNGW
                     TAYTRDGGLSCQYEHTLAITKDGPRILTSQGEEGTY"
     gene            3657..4580
                     /locus_tag="ACG8LA_001554"
     CDS             3657..4580
                     /locus_tag="ACG8LA_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HFQ0203859.1"
                     /translation="MKVWNKIKQNENLMRFIETTQKRITDSEMSTTSVVVAYYLLLSL
                     FPLIIAFGNILPFLHIDQETVLTYLREVIPETVYQFIGPAIKDLLTQSSGGLLSVSAL
                     AALWSASQSINALQIAMNKAYGVENRKNFLIVRFFSLIVIVLFMIAISGVTIVLGLGQ
                     LILDAIQPIVQIPVNFIDQFQTLKWPITLVALFVIMFLIYLIVPNAQLKLKTIIPGTI
                     FATVGWMLLSQVFSIYARYFATRISGYQIIGSFIVLMLWLNFAATIIILGGIINAVVQ
                     EYVTGHQIKKRRDPSRKWFNKLKTKFSHKKK"
     gene            complement(4805..5044)
                     /locus_tag="ACG8LA_001555"
     CDS             complement(4805..5044)
                     /locus_tag="ACG8LA_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004609551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0203860.1"
                     /translation="MSKDYGYPSFELICKASSGDEMAVKEILKFYDGYISKLCLRPFY
                     HSESGKIIMQVDEELKGEIHTDMMKAILKFEIGVK"
     gene            complement(5049..5468)
                     /locus_tag="ACG8LA_001556"
     CDS             complement(5049..5468)
                     /locus_tag="ACG8LA_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009588541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HFQ0203861.1"
                     /translation="MRTSSFEHIVRLQFNSLMLIVIKNKVKSRNRQLARHSKREVLFC
                     EIAETKQVERGTIDTCFYDCVSFKVLHFTIYVSDETLGTVLHRLSEKQRSAILLRYFQ
                     GMNDREISELYHVSRSAICSRRTRGLRKLKMLLSERK"
     gene            complement(5695..6933)
                     /gene="mef(H)"
                     /locus_tag="ACG8LA_001557"
                     /gene_synonym="mefH"
     CDS             complement(5695..6933)
                     /gene="mef(H)"
                     /locus_tag="ACG8LA_001557"
                     /gene_synonym="mefH"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_070509550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="macrolide efflux MFS transporter Mef(H)"
                     /protein_id="HFQ0203862.1"
                     /translation="MQAEKKLFNRDFILVVIGQIISLFGNAILRFALPYYLLKETGSS
                     ALFGIATACSFLPMVILSLVGGIIADRTNKRNIMVILDFVTAIIILVFYLSLGKIPII
                     PLFIVALMLLYGISGAYQPAVQASIPLLVSSDKLTVGNAIINQVNTLANFIGPAISGV
                     VFQFYGINPILIVSIICFTFSAIMEIFIHIPHQKRPREVGVIAVAKNDLKDSYTFLKK
                     EKPIFISVIFLVCIFNLVLSAVLIVGLPILISEVLKMPDTLYGFSQSALSLGGLCGGI
                     LTALVASKLKLKNLYTLLLICSVSVLLMGISLFLELPAIVSYWVVTVMCFVAMGVSTM
                     FVVQIYTLVQTQTPPQLVGKIMATLVAVAMCGQPIGQMVYGILFDVFIQETWVVMFVA
                     SIASIMISIYSKRIFQKLEI"
     gene            complement(7040..7675)
                     /locus_tag="ACG8LA_001558"
     CDS             complement(7040..7675)
                     /locus_tag="ACG8LA_001558"
                     /inference="COORDINATES: protein motif:HMM:NF012655.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFQ0203863.1"
                     /translation="MARNKYPEETVKLILDVSTKMFCEKGYDNTSLQDIINETKLSKG
                     AIYHHFDSKEDILKAIFQRIGNENAVIFAKIRDNDSLNGLEKLREIFKTAVFNSNQSV
                     LLTVSPQLLNNPRFLAMQIEQMYEIVVPEFVEPVLEQGIKDKSLEIENSHEIAEVIMV
                     LSNVWLNPLVEMTDKEGMEKRCNTFNALLNGIGIDTLLDEETISAFIQFCK"
     gene            complement(7789..7881)
                     /locus_tag="ACG8LA_001559"
                     /pseudo
     CDS             complement(7789..7881)
                     /locus_tag="ACG8LA_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323349.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
     gene            complement(8017..8652)
                     /locus_tag="ACG8LA_001560"
     CDS             complement(8017..8652)
                     /locus_tag="ACG8LA_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFQ0203864.1"
                     /translation="MEGYAMKISHLGNNIQTIRKFRGMKQQELADKIGINMQSLSKIE
                     RGLNYPAYETLEKIMEVLDVTPNELLSGEWKYVNQSEKEVCQFLRAEERLNAELKHGH
                     YDNFFDSEEEWLEYELEKLREYITDYINGKSIEASDLYPIKEFIQHLKFQKLLDRYDD
                     LYSMDMFGESIEGHKYKTPYQVVKMINPNSKEDMELLREVLRNNNFDDEDE"
     gene            9164..10306
                     /locus_tag="ACG8LA_001561"
     CDS             9164..10306
                     /locus_tag="ACG8LA_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005336080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HFQ0203865.1"
                     /translation="MNNLEFALEMKNKRLASGLSQGELASLTHVSRYSINRFENGKAN
                     ASKETQNIILRCLNYYICDKPFYLLVDYLSVRFPTTDALEVIRKVLGMKADYFIHYDY
                     GYYGYKEHYAYGEIKVMASDDEHMGVFLELKGAGSRNMEYVLQAQNRDWYSFLNRCLD
                     CGGVIRRFDLAINDMCGLLDIPVLSEKYRNGGAECRCKNYENVQGGKLSGKNRNLAST
                     LYIGSKASTKYFCLYEKQKEQATKKKHTDIINRFEIRLRDKKAVQAVEELLLTYNPHG
                     LVFYLITDFVEFPDYPLWEIFISHDSLPFEMNPVPVNMERTLQWLERQVMPSIVMIEE
                     IDRLTGSNYMKMIDECTHLSEKQEMLVEQMCTDISDVIESEGVFYE"
     gene            10299..10505
                     /locus_tag="ACG8LA_001562"
     CDS             10299..10505
                     /locus_tag="ACG8LA_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HFQ0203866.1"
                     /translation="MSNTQDIPVWEKYTLTIEEASKYFRIGENKLRRLAEENKDAGWL
                     IMNGNRIQIKRRQFEKVIDKLDAI"
     gene            10584..11777
                     /locus_tag="ACG8LA_001563"
     CDS             10584..11777
                     /locus_tag="ACG8LA_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005336078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFQ0203867.1"
                     /translation="MKEKRRDNKGRILHTGESQRTDGKYLYKYVDALGNTKYVYAWRL
                     TPTDPTPKGKREKPSLRELEQQIRRDIEDGIDSTGKKMTLCQLYAKQNAQRTNVKKST
                     QKQREQLMRLLKEDKLGARSIDTIKPSDAKEWALRMKDKGFSYNTINNHKRSLKASFY
                     IAIQDDYVRKNPFDFKLSEVIENDTKEKVALTEEQEQALLSFIKTDNVYHKHYDDVLI
                     LLKTGLRISELCGLTVADIDFKNEVVIIDHQLLKSKEQGYYIETPKTKSGIRQVPLSK
                     ETIQAFQRVINSRPKIKSIEVDGHSGFVFINPKGNPKVAIDYNALFIRMVKKYNKHHK
                     DNPLPHITPHTLRHTFCTRLASKNMNPKDLQYIMGHSNISITMNWYAHASIDTAKSEV
                     QRLIA"
     gene            11982..13121
                     /locus_tag="ACG8LA_001564"
     CDS             11982..13121
                     /locus_tag="ACG8LA_001564"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MraY family glycosyltransferase"
                     /protein_id="HFQ0203868.1"
                     /translation="MLVSFSMVIRFFLTILLSLILTPVFKIISVQTGMVDKPNERRIN
                     KVPMPSAGGLPIFISFVISTLFLFRKIIPQSYIVPILIASLVIIVTGVLDDKYELTPK
                     QKSIGILIASLIIYFVADIRIDSFTLPFIGYIQLGWLSFPVTIFWIFGITNAVNLIDG
                     LDGLAAGISLIGLITIGIIGYFFLHASTVYIPVVIFCLVASIIGFFPYNFYPAKIYLG
                     DTGALFLGFMMAVLSLQGLKNVTFVSSISLLIVMGVPVTDTFFAIIRRKANRVSFSTA
                     DKKHLHHRLISLGFTHKGAVLTIYAMALMFSFTAMVMNYTGRIGTIILIIAMLFAAIL
                     LFELIGLINEKHQFILKTLRFLGNKEYRTQVKQKYLKKWNRHIDE"
     gene            13114..13914
                     /locus_tag="ACG8LA_001565"
     CDS             13114..13914
                     /locus_tag="ACG8LA_001565"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFQ0203869.1"
                     /translation="MNNKLNQPILISIVTANSDKIFRTLDNFISTVKDETAVKIRIFD
                     NNSLPEYKKRLTEYRKYPYIDIYFHDENSGFGYGHNHNLIASDSRYGIICNPDILVDE
                     ETVTALVLLLKEHPECAMLAPKILNEDGTTQHLIREQLAVFDYVLRFVPFKWVKKKFD
                     KRLAVFECRGLPTDANSYVRMISGSFMVADIDKFKEIKGFDERFFMYFEDNDLCLSFE
                     KAGYKLLYTPFYAVIHFYGKGAHRNAKLFRVFLTSMMKFFNKWGWRFF"
     gene            13914..14741
                     /locus_tag="ACG8LA_001566"
     CDS             13914..14741
                     /locus_tag="ACG8LA_001566"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFQ0203870.1"
                     /translation="MKPEILVVVVLYQQLFSQSPAYGPLSKALSEKQIQLIIYDNSPQ
                     RQQNELFEKENIVYHHDPQNPGLAVAYNFALSQADEGTRCLVTLDQDTRLVDDYFELL
                     RKVTFTDECVAAVPMIFSGSRQVSPLYSDRYINRTAQAVEVEGPTAERIMAINSGVAW
                     SVKFLKKIGGFNPAFSLDFLDHWLFWKVDQLEKTVEILPVRMEHDLSVLDYEKVSSNR
                     YRSILQAENRFYHEYDQRHLSSHRRQLLLRTAKQFLTVKNRHIWRMTLRSYVKNWKV"
     gene            14746..15453
                     /locus_tag="ACG8LA_001567"
     CDS             14746..15453
                     /locus_tag="ACG8LA_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFQ0203871.1"
                     /translation="MRSVCIATFNGGRYLREQLDSILSQLSAEDEVVISDDGSVDDTW
                     DILTEYAEKDKRIQLFSGPRQGLIANFGYAIQQTKGDLIFLADQDDVWLETKVKKITD
                     YFEQNPDQLVVVSDLIIVDSELQEIHDSYFSFRNSKEGWLNNVIRSHYIGAGMAFRSS
                     LKPDILPIPSEVPMHDMWIGLLGGKKTGFLREPLTLYRRHDLNASEIETHSKLRQKIS
                     WRVHLITALIKRKWFKR"
     gene            15553..16419
                     /gene="rfbA"
                     /locus_tag="ACG8LA_001568"
     CDS             15553..16419
                     /gene="rfbA"
                     /locus_tag="ACG8LA_001568"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008879 - glucose-1-phosphate
                     thymidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0045226 - extracellular polysaccharide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HFQ0203872.1"
                     /translation="MKGIILAGGSGTRLYPLTKATSKQLMPIYDKPMIYYPMSTLMLA
                     GIKEILIISTPQDTPRFKELFGNGNDLGLQIEYAVQESPDGLAQAFIIGEEFIGDDSV
                     CLVLGDNIYYGGGLSKMLQRAASKDTGATVFGYHVNDPERFGVVEFDENMQALSIEEK
                     PAQPKSNYAVTGLYFYDNEVISIAKGIKPSERGELEITDVNKAYLDKGKLSVELMGRG
                     FAWLDTGTHESLLEASTFIETIEKRQNLKVACLEEIAYRMGYIDKEQLLALAQPLKKN
                     QYGQYLLNLAAE"
     gene            16433..17005
                     /gene="rfbC"
                     /locus_tag="ACG8LA_001569"
     CDS             16433..17005
                     /gene="rfbC"
                     /locus_tag="ACG8LA_001569"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010771301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008830 - dTDP-4-dehydrorhamnose
                     3,5-epimerase activity [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HFQ0203873.1"
                     /translation="MKVTDTKLTDVKIVEMDVFGDHRGFFTESYSKAKFAEHGLKYDF
                     VQDNHSLSAEAGVLRGLHFQKGEAAQTKLIRVVTGAVLDVVVDIRKGSPTYGQWDGFI
                     LSEHNHRQLLVPKGYAHGFVTLTPNVNFLYKCDNYYNAEADGGIAFDDPDLAIDWPID
                     PSRAIMSEKDHRHPTLKEFEAENPFVYGEI"
     gene            17027..18055
                     /gene="rfbB"
                     /locus_tag="ACG8LA_001570"
     CDS             17027..18055
                     /gene="rfbB"
                     /locus_tag="ACG8LA_001570"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008460 - dTDP-glucose 4,6-dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009225 - nucleotide-sugar metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HFQ0203874.1"
                     /translation="MKNIIVTGGAGFIGSNFVHYVVNNHPEVHVTVLDKLTYAGNKEN
                     LAGLPSDRVELVVGDVADAELVDRLVKEADAVVHYAAESHNDNSLKDPFPFVQTNIIG
                     TYTLLEACRKYDVRYHHVSTDEVYGDLPLREDLPGHGEGEGEKFTAETPYNPSSPYSS
                     TKAGSDLLVKAWVRSFGLRATISNCSNNYGPYQHIEKFIPRQVTNILSGIRPKLYGEG
                     KNVRDWIHTNDHSSAVWLILTKGRIGETYLIGADGEEDNKTVMELILEMMGQPKDAYD
                     HVNDRAGHDLRYAIDSTKLREELGWKPEFTNFRDGLADTIKWYEEHEDWWKKEKEAVE
                     AAYAKNGQ"
     gene            18153..19004
                     /gene="rfbD"
                     /locus_tag="ACG8LA_001571"
     CDS             18153..19004
                     /gene="rfbD"
                     /locus_tag="ACG8LA_001571"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008831 - dTDP-4-dehydrorhamnose reductase
                     activity [Evidence IEA];
                     GO_process: GO:0009243 - O antigen biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HFQ0203875.1"
                     /translation="MFLLTGGNGQLGTELRHLLDEKNLQYVSTDAKDLDITDAEKTMA
                     YITELKPDVIFHCAAYTAVDKAEEEAKELDEKINVDGTRNVALAAKAVNAQFVYISTD
                     YVFDGKNKNVEYEVDDQTNPLNEYGRTKLLGEKAVEEILEDYYIIRTSWVFGIYGHNF
                     VFTMQRLAETRDKLTVVNDQFGRPTWTRTLAEFMVYVIEEKAPFGIYHLSNENSCSWY
                     EFAKEILKDTDVEVAPVTSEEFPQKATRPQYSVMSLKKTEELGFVIPTWQEALAQMLE
                     AAKKMNK"
     gene            19038..21071
                     /locus_tag="ACG8LA_001572"
     CDS             19038..21071
                     /locus_tag="ACG8LA_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0203876.1"
                     /translation="MEKQTRSARRKEKPKANQADSNLVLDLFLKLRYLIGVLVIVVIV
                     TFNLNGSSLGVWDKYVSQRDDGKKTDVIFGQNREVRSDEWLVQTPFYLSQAEEDFPLV
                     NEDYSLNGQNMIIAYNSPVKDITVIGKPFNWGFFFLGRDRGLSFYWAMKLVVMVLLGF
                     EVLMILTKRKKALSLIGAFALTFSPAVQWWFMQHVGDLIFFTLGLMTAFYHYFYNHDK
                     KWLRTLMMLLVVIFGIGFILVIYPAHQVMLAYLLIFYFVGLLIYYSKKVSWDLLDVVL
                     IGGAVLFIGGVMVHFWLTSKDALLASLNTLYPGKRVSTGGKWTIGEFFSFLTNWKIPF
                     EDINYSNNSEVALFYHFFPTVFLASPFVLFGKKDSEQKLLGRILMIFCLFSIFWITVG
                     LPKWLAEITLLSYVPPLRAILTFSFAACLLSIWFIAYIWREDVIPIWYKFILLAVNAW
                     SYFYAITHSKMDNYFSDFETIAVAVLGTVILAFALFGWRRLFYLAFAALVIVSGFFVN
                     PVVEGTGAIFEKTLAKEIQKIDQQDPGKVWLSEDELYNFTPTLGVKSFNTVRFYPDIA
                     AWKKIDPKEEYEKYYNRYAHTRAFIAKEDTKFILDRPDMFSVTLNFEDAEKLGIDYVI
                     SKRPLTDYNQLYEAQFTQLYGPDKDGYMIFKVEYPDYPDVPQTQTQENQLVVQ"
     gene            21115..22395
                     /locus_tag="ACG8LA_001573"
     CDS             21115..22395
                     /locus_tag="ACG8LA_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EpaQ family protein"
                     /protein_id="HFQ0203877.1"
                     /translation="MEIIQAIVQKFVNKMSVGFLLLLLTLVFFVWTAGLGFPATLFIY
                     NNSSLLIAFSVAILLILNVYKAKGVDFLYLGVALALFIFFSYFRELRNESLFGDLLFP
                     LIILFCLVIKWIEWTKWDRGIYLIVFSVFLGITLYRVFTEIQVPEGQSIWAPGNSLSD
                     IWINTNIIGSSLMTLALLISGFASSFERWYVRIIGAVAVVAAFLGIWVCQSRGALVAL
                     IVFAILDLLPKSLMRVIRAPFIAYTVTILLALPISYLAAVSEKVNLFTGREDIWHKFY
                     QTLGEKSEQILLGMKTFIFQRGNQFLGNHNSYNSILNIYGLIGFGIAALLLILFIGRL
                     TLKADLSNGQMTFIWAFFAVMMQSFMEDTLTSYPWVPIIYILLAMAVHRYDEPEVAEE
                     FYVMEEAYDDMTYDDTSYEEQPDSAHSSRIQRYH"
     gene            22605..23411
                     /locus_tag="ACG8LA_001574"
     CDS             22605..23411
                     /locus_tag="ACG8LA_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFQ0203878.1"
                     /translation="MFKDLYLFMKDIYQNRKLLLQFSINDFKSRYAGSFLGILWAFIN
                     PLFTVLIYWLVFGVGLKAQMIDAKYPFIVYLVTGMIPWFFFSDAFASTTVVFREYTYL
                     VKKVVFNIRILPTTKILSNLYTHLFFILIGIAVALINGIYPSAMSLQLIYYLFCMCAF
                     LTGLTWLTASIQPFLPDIMQLITIVLQLIMWTLPILWSPNQFDSGLVSILKLNPLYYV
                     VQGYRESFLSEAWFWEHGTYTLYFWVFTLVMFVIGSAVFRRLKPHFSDVL"
     gene            23423..24643
                     /locus_tag="ACG8LA_001575"
     CDS             23423..24643
                     /locus_tag="ACG8LA_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0203879.1"
                     /translation="MTEYAIRLKDITKSYNMYAKPSDRFREALNPFKKSYHDVFYALK
                     NVNVEIKKGEMIGFVGENGSGKSTMLKIITGVLTPTSGTMEIEGKISALLELGSGFNP
                     EYSGYENIYLNGMVLGFSREEVDEMVDDIIEFADIGDHIYQPVKTYSSGMFVRLAFAV
                     AINVNPDILIVDEALAVGDLEFQLKCMEKFTEIKNSGKTILFVSHDISSIRRFCDRSY
                     WLKNGEVVEYGDTMEVTTNYENFLKKKSVKTVDRNKNQVERFAAPDIVDVTKAELLDK
                     DKNPVDMLEQGEKLYVKVTYEVKDDTIKNPVLGIALRTVDNFYVCGLNTLLDGIKIPW
                     KKGENIFYLEYEKLGLLAGEYYFDVAVFEENATVPLVYKTKYMNLFVSGSYIGEGIVV
                     LDHKWEEGTHSNEI"
     gene            24633..26219
                     /locus_tag="ACG8LA_001576"
     CDS             24633..26219
                     /locus_tag="ACG8LA_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFQ0203880.1"
                     /translation="MKYDFEMDLDEQSSVGKIAAQIKPGSKVLEFGPGNGRLTKHLIG
                     AKQCEVSIVELDKELFDFVSEFAQDGFYGDIESFEWANYYAGQTFDYVLFADVLEHLV
                     DPGKTLKKVREFLNEEGEILITFPNLAHNSVMIDLFNNQLPWASYGLLDETHNSFYTH
                     DGFQKVFEKAGLFINIEDYLYLAVGDTELKSTYEELPEAVRYDFKMRPFGEVYQYFFS
                     LMKHPVAQSSIAEPQNSNYVKVLEVTQQTKQDETIQQIPFNNFTGENETLSFPVSETT
                     ERMVFRFAQQPSFIEFSAEAAGEKLTFIDSNAVVKTVNDCYLFDGKELPEFVLTDISG
                     KEVTIHCHYRFIGELTPTMKELLETIRPMAEVTKQLSEKNDELERENHHLLEENTRLD
                     HTLKTTTNRYCTLLESDEWTIKHRLGRRKKETSKKIQEKELSICIDEKIWDAETKILK
                     IIGWGIANSDRQPLSYKLSADQSPFFEAIPVSREEVNQAEQLAKGTEAGFELRILCEQ
                     ERSFLVEAVAQNGQSWIIEM"
     gene            26258..28396
                     /locus_tag="ACG8LA_001577"
     CDS             26258..28396
                     /locus_tag="ACG8LA_001577"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006486 - protein glycosylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFQ0203881.1"
                     /translation="MQKKEIAVFIDQITRERATGDLLIVGWAIDEVTKEIPTIKVEKE
                     NVIAEATHVVRLDINHLYNLDVKTQSGFKVRLSGKMRGKAILDFQTARHQNGIAVKLN
                     GKYPYDDGIESSWERKKRLLKKGINYARTHGVKKAIRRVKLELKPGSIDYAEWISRHE
                     KPDLKEQRKEAQGFAYRPLISILMPVYNVEIKWLEKCIDSVLDQTYDHWELCISDDAS
                     TDPAIRKCLESYQAKDDRIKVVFRKENGHISLATNSALEIAEGEFIALLDNDDELPPF
                     ALYEVAKVLNVHPELDVIYSDEDKIDADGNRFDPHFKADWSPDTLMGNNYISHLGVYR
                     TSIVKELGGFRKGYEGSQDYDLVLRVTEQIPADHIYHIDRVLYHWRTIPGSTASNGEA
                     KSYIYDSGVKALTDALSRRNIKGSVRPGRISGFYEIAYDVLQEDLVSVIIPTKNGYED
                     LKTCVDSIIEKTSYSNYEIIIADNGSTDPKMQELFAEYKHQLKDRFIVELIDIPFNYS
                     RINNLAAEKANGKYFLFLNNDTEVIEPDWMTVMVSYAQFDRIGCVGAKLFYPDDTTQH
                     AGVLLGIGGVAGHALNNYDRTHCGYFGRLVIDVNYLAVTAACMMVKAADFNAVNGFDE
                     TLEVAFNDVDLCLKVYELGRYNVYAHQAELYHFESKSRGYEDTPEKQRRFAGEIKKMQ
                     DKWPAYIAHDPFYNDNLTKEGIGDFSLRPD"
     gene            complement(28764..29747)
                     /locus_tag="ACG8LA_001578"
     CDS             complement(28764..29747)
                     /locus_tag="ACG8LA_001578"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase domain-containing protein"
                     /protein_id="HFQ0203882.1"
                     /translation="MNKQELHDFIGFRQPNICQIVAYKDGVEVYTDEWNGYKKDDTCH
                     IMSATKSIVSLLIGIALEQGLIKSIDDKVLDYFPEYKVKRGEKTIYAITIKHLLTMKA
                     PYKCKGDPWTKVCSSEDWTKTSLDLLGGRKGITGEFNYQTVCLHILTGLLYQTSKLTT
                     VDFANKYLFDPIGIPNHVNYYAETAEEHKQFTMDKSPKTNVWFCDPLNIGTAGYGLCL
                     SASDLAKIGVLCLNKGMYKGKQIVPPMWINEMFKPRTSALEDLQNMRYGYLWWVLDSE
                     NEIYSAIGNSGNVLYIDAKNNLVISITSYFKPMIIDRVAFVEEYLKPFILK"
     gene            30125..31516
                     /locus_tag="ACG8LA_001579"
     CDS             30125..31516
                     /locus_tag="ACG8LA_001579"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HFQ0203883.1"
                     /translation="MNKNGEWSAARRIFIILMDVIVYNAAIYSSFLLKFRGEIPLRNL
                     ETFQHSAIIISVIFIALNILLGAYVFYNRMISDIVFVTVIGQVLMTLGIMVVTFAGRW
                     FAFPRLVILLSFVLGTLFLSIYRILVYKLYLRVSRDKKVVIIGLEKDVAPAIQNFGSK
                     KNNKHKVEAVILDNYYANIKNMIKDIDIVYLASHIEETEKIKIYQLVTKNEKKLFLNT
                     TFENLTLINPNIMNFEDESIIEASGFRIQPEYELFKRLFDIIVSLVLLVIASPFMLFT
                     AILVKVTSPGPIIYKQVRITKNQKEFSIYKFRSMTATAEAKSGPVLAKSNDARVTPVG
                     KFIRAVRFDELPQIFNVLKGDMSIVGPRPERPFFVDQFNAENPYYYLRHNVRAGITGY
                     AQVYGKYVSDYNSKLRFDLLYIKKYSLMLDLKILLQTIKILFDKMSSQGLEEDENVIS
                     LAEIAFPNEKIFR"
     gene            31532..32572
                     /locus_tag="ACG8LA_001580"
     CDS             31532..32572
                     /locus_tag="ACG8LA_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFQ0203884.1"
                     /translation="MNNPKFSIIVPVYNAEATIGRTIDILKELDYEEYEVVLVNDGST
                     DQTQEIIQELIENDERFELITTTNQGPGLARNEGIRQSKGEYLLFFDADDTPVKTILS
                     DYDHLLEKSPKADLVVSSFVFRTMDEGRIVSEKENLVTECHYLTHEEFIKDMYQLMNE
                     QLMYVVWNKCYRSDILKNNQILFKTYNSCEDRIFNLHYYEYCHQVIMNPKVEYIYEFE
                     GGKGITNQYRPNKFETFKEFYSLANTVTDDINKDGMAALLLKGTTSVIFSIYSTSART
                     SKEKKDEAKQILSDPVIREAKQIAKTDSSAKKITKLLYNMPAPLFLSAVKVGSFVEVK
                     MPGLMAALKRVY"
     gene            32591..>32765
                     /locus_tag="ACG8LA_001581"
     CDS             32591..>32765
                     /locus_tag="ACG8LA_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 1 protein"
                     /protein_id="HFQ0203885.1"
                     /translation="MKRILHFQGRMGLGGAESFMMNLYRKIDRTNYQFDFLIYEDYAD
                     VQDYHSEIERLGGR"
BASE COUNT        10539 a         5692 c         6479 g        10055 t
ORIGIN      
        1 tattttttgc atgtgtgcga aagtatactc aagcccaatc gccatttcgg aaaatcggta
       61 ctgtagagcc atcttcacgg attccgtcga tatccatctt gtcagatcct accatgaaat
      121 ctacgtgggt ttgacttcta ttcaatccag cttctgctaa ttcttcatcg gacatttctg
      181 taccgccttt cacactgaag gcataagcag aacctagtgc taagtgattc gatgcgtttt
      241 catcaaataa tgtattgaaa aagatgatgc cagattgaga aataggtgaa gggtcaggta
      301 caagtgcgac ttctcctaaa cgacgcgcac cttcatctgt atcaagcagt tttgctaaga
      361 catcttctcc ttgttcggca gaaaaatcaa caacttttcc atctttaaaa gtaaatttca
      421 tacccgagat gatggtgcca gcataactca gtggctttgt acttgaaatg taaccatcta
      481 ctcgatgact gtcaggtgct gtgaacactt cttccgtcgg catatttgcc atgaattttt
      541 ctccacgagc attatagctt ccagcgcctt cccaaagatg gtttttaggc aatccgataa
      601 tgatatctgt accgggagca gtatagtgaa gggcagaaaa ttgttctcga ttcaattctt
      661 ctgctttttt tgctaatttt tcatcatgct tcttccatgc taagacaggg tcttcttcat
      721 agacacgagt cgttttgaaa atctgatccc ataatgcctc aacttgtttt tcttctggca
      781 gttctgggaa gacttttgct gcccattgtt taccagccgc agccacgaca gtccaactga
      841 ctttatttgc ttgagttgcc ttgcgtaaat tcattagtgc tttgccattc gctgattgat
      901 aagacgctac tcgatggcta tctacaccag caaatgcatc gggatcggca gaaacaacgc
      961 tgatcctgct tgctcctttt tcaagccatt catccgcttg atcgatttta gattgtggta
     1021 cattctcaat acgatccgtt gcagcatgta aaagaaattc tctttggatc tggtcgtcag
     1081 tccattgaac gataacctca gcggctccta gtttataagc ttcttgtgtg atcaatcgag
     1141 caaggggtgc ctgttccacg ctgatctgta aaacaactgt gtgtcctttt tctgtggcta
     1201 cgccagtttc tgcaattaag cgtgcatatt tttttagaag ttcattaaaa tcagataaca
     1261 taataaaaat tcctcctcac cattttttct ggtaactatt agcatgatac catttaatta
     1321 tgattcaaac aatgaggctt taaataaaaa aaggaggtta tttttttaag gttaagtttc
     1381 atgatatatg ttactacttg ctatttcagc ttgtgaagaa aatcaaaaac taattttgca
     1441 tatcaaaaaa aacatgttac aatgaaatta atcaatggtg gaagcgttat aaaaaaatta
     1501 aggagattaa aaaatatggc aagaaaaaag acgattacta gagaacagat tttggcagct
     1561 gcttatgaag tagctgccac cgatggattt acacgattta ctgcgagaaa catcgcgaac
     1621 aaaatgaatt gttccacgca accgatttat cttgagttta aaaatatgga tgacttgaga
     1681 caagctcttt ttgagcagat ctatgatcat ttacaatatg aagtgttcac tgttgagcat
     1741 acagggaata cgattatcga tcttgctttt aattatatcc attttgcaag aagagagaag
     1801 aagttgtatc gttcactgta cttagaagaa tatggtggag gaaaagagat gcagaatttc
     1861 tcttatactt actttgtgaa tacagtgaaa cgcgatccag cttatgtgaa tctttcagaa
     1921 gagcagatcg aatctttgta taatgggaca tggatcatag ctactgggat cgcagctttg
     1981 atgtcttcaa gcatcatcca tccaactgat gaacagattg aaaagatgat ccaagacagt
     2041 atagatgcta tcttgaaatt caaagaacca atcgaaatcg attgaatata ctcaaaagtt
     2101 ccacaaatca gtaggtaaca agagatgtgt caaaataagg aaaagttcgt ttttcttaca
     2161 gcgtatgcat ttttaactcc cgaagaactc ttccatgaat gcaatgaata aaagagccat
     2221 acagattgaa taaatctgga tggctctttt attgcaagta tattaaattt ttgcgactag
     2281 ttctttagcg aaagcttcta aattttcgat atcttcttct tcagcattca gatccacttt
     2341 aacattttcg gctccttttg atgcgcctgt ttttgcaaaa gcagcatcga aatcatccac
     2401 cgatttgcag aattcatcgt aaaaagtatc accagatccg cagacaccgt aaatttttcc
     2461 caatagatcc aattcttgca agtcttcata aaagtctacg atctcatcag gcagatcgcc
     2521 atcatcgtat gtataagtag ctactacgca aatatctgcc tcctcgaatt catctgcatc
     2581 tacttgggta cattcgttga tttcgacttc gatatccaga ttttcaaatg cttctgcaac
     2641 aatatcggcg atttcttcag tgtttcctgt catgctagca tatacgattt ttgctaaagc
     2701 catgatgtgc ctcctcgttt ataattattt aacaattatg aattatacca aaacatcatt
     2761 gaaaagaaaa taaaacctag agacacctgg ggaatgtcat ttggctaaat gtatgccgct
     2821 atgttaaaat gagagggatt tgtaaaaagg agacgaaaat atgattactt taaaatcagc
     2881 acgtgaaatt gaaatgatgg cagaatctgg agctttatta gcagatgtac ataaaaatct
     2941 gcgtgatttt ataaaaccag gaatcacaag ttgggatatt gaggtatttg tcagaaacta
     3001 tatcgagagt catggcggaa ttgctgcgca aattggcttt gaagggtatg aatatgcgac
     3061 ttgtatcagt ataaatgatg aaatttgtca tggattccct cgtaaaaagc ctttgaaaaa
     3121 cggtgatttg gtaaaagtcg atatgtgtat cgatttgaaa ggcggcattt ctgattcttg
     3181 ttgggcctat gtagttggag aatctacacc tgagatcgac cgattgatgg aagtaacgaa
     3241 gaaagctttg tacatcggta ttgagcaagc acaagtaggg aatcggattg gtgacatcgg
     3301 tcatgctatc caaacttatg tagaaggcga aaatctagcg atcgttcgtg attttattgg
     3361 tcatggcgtt ggtcctacga ttcatgaaga accagcagtt cctcattacg gagaagctgg
     3421 aaaagggttg cggttgaaag aaggcatggt tatcacgatc gaacctatgg ttaataccgg
     3481 aacttggaaa atgaaaatgg atcctaacgg ctggactgcg tatacaagag acggcggact
     3541 ttcttgccaa tatgaacata cattggctat tactaaagat ggtccaagaa ttttgacatc
     3601 acaaggagaa gaaggcactt attgatctat ccagtcaata ggtacgggag aggtacatga
     3661 aagtttggaa caaaataaaa caaaatgaaa atctgatgcg ctttattgag acgactcaaa
     3721 agcgcatcac tgattcagaa atgagtacga cctctgtcgt cgttgcttat tatttactct
     3781 tgtctttatt tccattgatt attgcttttg gtaatatttt accgtttctc cacatcgatc
     3841 aagagactgt actgacctat ttacgagaag tgattcctga gaccgtttac cagtttatcg
     3901 gtcctgcaat caaagacctt ttgacacaaa gttcaggagg cttgttatcc gtttctgcat
     3961 tagcggcttt atggtctgca agtcaaagta tcaatgcttt gcaaattgcg atgaataaag
     4021 cgtatggcgt agaaaataga aaaaattttt tgatcgtccg tttcttctca ctaattgtca
     4081 ttgtcttgtt catgattgct attagtgggg taactatcgt tcttgggttg ggacagctga
     4141 ttttggatgc tattcagcca atcgtacaaa tacccgtgaa ctttatcgat cagttccaaa
     4201 ctttgaagtg gccaatcaca ttggtagctt tatttgtcat catgttcttg atttatttaa
     4261 ttgtccctaa tgctcagttg aagttgaaga cgatcattcc gggcacgatc ttcgctactg
     4321 tcggctggat gctgttatca caagtgttta gtatctatgc taggtatttt gcaacgagga
     4381 tcagcggtta tcagatcata ggaagtttta ttgtactcat gctttggctt aattttgctg
     4441 ctacgatcat cattttgggc ggaatcatca atgcagttgt tcaagaatac gtgacgggtc
     4501 atcaaatcaa aaaacgtcga gatccaagcc gaaaatggtt caataaattg aaaactaaat
     4561 tttctcataa aaaaaagtag aaacaagagt tcttattgta aatttatatc agtaatttat
     4621 ttgaaatttt atatctaatt ttcaattatc cgcataaaca ctatacattc aagcattttg
     4681 aagtatagaa aaacactcat cttaccacga atttaccacg attgaatgag ccttgatatg
     4741 accgtaaaac tactaaggga gatagcacga aactgtgtat ctcccgattt ttttatacag
     4801 ttgattactt cactccgatt tcaaatttca atattgcttt catcatgtct gtatgaattt
     4861 ctccttttag ttcttcatca acctgcataa tgattttacc actttcagag tggtaaaaag
     4921 gacgcaagca taatttagaa atataaccgt cataaaactt caaaatctct ttaactgcca
     4981 tttcatctcc gcttgacgct ttgcaaatca attcaaaaga gggatagcca taatctttac
     5041 tcatttcttt acttcctttc gctcaaaagc atttttaact tccttagtcc tctagttctt
     5101 ctactgcaaa tagcagaacg tgatacatgg tacagttctg aaatttctct gtcgttcatt
     5161 ccttgaaaat aacgtaataa aatcgcacta cgctgttttt ctgacagtct atgtaaaact
     5221 gtaccaagtg tttcatcaga tacataaatt gtaaagtgca agactttaaa tgatacacaa
     5281 tcataaaaac aggtatcaat cgttccacgt tcaacttgtt tcgtttcggc tatttcacaa
     5341 aacaatactt cacgtttaga atgtcttgca agctgtctgt ttcgactttt cactttgttc
     5401 ttaatgacaa tcagcattaa agaattgaac tgtaatctga cgatatgctc gaaagaagat
     5461 gtcctcataa tctcaccccc tttctgctaa tgctgaaata tataaacgga ataccgttta
     5521 taccctttag aaatacagaa aaatggtaag aaaaaagccc acacaaaaca tatatttgtg
     5581 cgagccttaa atactgcaat attactcttt cttttataac actatccttt tagcagattt
     5641 caaattttct tttatatatt gtttttagcc taacatacta tttaacccct tgtattatat
     5701 ctctaacttt tgaaaaattc tttttgaata tattgaaatc atgattgaag caatagaagc
     5761 tacaaacata acaacccatg tttcttgtat aaatacatcg aataaaatac cgtaaaccat
     5821 ttgtccaata ggttgaccgc acatagcaac tgctaccagc gtagccatta tctttcctac
     5881 taattgcggt ggtgtttgtg tctgaacaag agtgtaaatt tgaacaacaa acatagtaga
     5941 tacacccata gccacaaagc acatcactgt aactacccag taggaaacta ttgcaggcaa
     6001 ttctaaaaat agcgaaattc ccataagtaa aacagaaaca gaacaaataa gtaacaaggt
     6061 ataaaggttt tttagtttta actttgaagc aacaagagct gttaaaatac caccacataa
     6121 accacctaat gataatgctg attgtgaaaa accatatagt gtatctggca tttttaaaac
     6181 ttcagaaatt aagataggca gaccaacaat taaaacagca cttaaaacca aattgaaaat
     6241 gcaaaccaaa aagattacgg atataaaaat gggtttctcc tttttcaaaa aggtataact
     6301 atcttttaaa tcgtttttag caactgcaat tacacctact tcacgaggtc ttttttggtg
     6361 tggaatatgg ataaaaattt ccataatggc tgaaaaagta aaacatataa tactaacaat
     6421 taaaatggga ttgataccat aaaattgaaa aactactccg cttatagctg gtccgataaa
     6481 gtttgctaaa gtatttactt gatttattat agcattaccg acggtaagtt tatctgatga
     6541 taccaataga ggaatacttg cttgtaccgc tggttgatat gcaccagaaa taccataaag
     6601 taacatcaaa gcaacaataa acaaaggtat gataggaatt tttcccaatg acaaataaaa
     6661 tactaaaatt atgattgctg ttacaaaatc tagtatgacc ataatgtttc ttttatttgt
     6721 cctgtcagca ataataccac ctaccagcga caaaataacc ataggtaaaa aagagcaggc
     6781 tgtagcaata ccaaacaaag ctgatgaacc agtttctttt aacaaatagt acggtaatgc
     6841 aaatcgtagg atagcgtttc caaataaaga aattatctgt cctataacaa caagtataaa
     6901 atcacgatta aaaagttttt tttctgcttg cataaaatct ctccttttta tttaatcaaa
     6961 cagaccgtcg gtttatataa tggtttaaat aaactgctct tttatagagc agtctatcgt
     7021 atagggataa caaatacagt tatttacaaa actgtataaa tgcagaaatt gtttcttcgt
     7081 ctaataatgt gtctatgcct attccattta aaagggcatt gaatgtattg caacgttttt
     7141 ccataccctc tttatccgtc atttcaacta atgggttgag ccatacatta cttaatacca
     7201 tgataacttc tgcaatttca tgtgaatttt caatctccaa agacttatcc ttgatacctt
     7261 gttctaaaac gggttcaaca aattcaggta ctacaatttc atacatttgt tctatttgca
     7321 tagcaagaaa acgaggattg tttaatagtt gaggagaaac tgtcaataaa acgctttggt
     7381 tagaattgaa taccgctgtc ttaaatattt ctcttaactt ttctaaaccg tttaaactat
     7441 cgttatctct aattttagca aatattactg cattttcatt tccaattctt tgaaaaattg
     7501 cttttaaaat atcttccttt gaatcgaaat gatgataaat agcaccttta gaaagttttg
     7561 tttcattgat aatatcttgc aatgatgtgt tatcatatcc tttttcacaa aacatttttg
     7621 tagaaacatc taaaatgagt tttactgttt cttctggata tttatttcgt gccataactt
     7681 acctccaata caaaccgttg gtctgattaa agtatatctt agtattttat gcttgtcaat
     7741 ataaagactt gcaattttat aaaaatgcag aatgcaagcc tttttcattt attctacaat
     7801 cttccagttg ctttccttat gcggtgtcaa ttcatactgt gatacctgcg ttgcctttgc
     7861 ctgatttacc acaaatcaga ttttatccct ttcttcctct tgattgccca caacagaaaa
     7921 gaaaaagccc tgtcaagagc tttgccacca ttggtggtgc tttgcactct tgatcgggct
     7981 ttttgtttgc tgtatcttct cgcaagagga aaaaagttac tcgtcctcat catcaaaatt
     8041 gttattcctt aatacttctc gtaacagttc catatcttct tttgagttcg ggtttatcat
     8101 tttcacgact tgataaggtg tcttatactt atgtccctct atgctttccc caaacatatc
     8161 catactgtat aaatcatcat agcggtctaa taatttttga aacttcaaat gctggataaa
     8221 ttctttgatt gggtaaaggt cggacgcttc aatgcttttc ccgttgatat agtctgtaat
     8281 atattcccgt aacttttcta actcatattc cagccattct tcctcgctgt caaagaagtt
     8341 atcatagtgt ccatgtttca gttctgcatt tagacgttct tcggctctta aaaactgaca
     8401 gacttccttt tcagattgat tgacatactt ccattctccc gacaacaatt cattgggcgt
     8461 aacgtccagc acttccatta tcttttccag cgtttcatag gcaggatagt tcaaccctct
     8521 ttcaatcttg gaaaggctct gcatattgat accgattttg tccgcaagtt cctgttgttt
     8581 cattccccta aattttctta tggtctgtat attatttcct aaatggctta ttttcattgc
     8641 ataaccctcc atatctcgtt atatcttcgc tattataagt ctatcatgct taatatgatt
     8701 tgtaaaggca aaaaaagata ttgacaaata agcatataag aattactatg ttcttgtaat
     8761 cgaataagca caatagaatg aaatataaaa acattcaaaa agaaatacct atctgattaa
     8821 atccgtagat atgaatatcg gttgaaatgg aacttgttag aaaaggcaaa acagaacttg
     8881 ctgacaaagt atttctgaca cggtggcgga agcctctcag gcttaccgcc atgacacctt
     8941 gtgtcaaggg gaagaaatgc tttgtcggct ggcgagcctg cgagccttgt ctgtgccccc
     9001 gttatctaac aggggggcac tatttcacaa aagacaagtc aaaaaccata cacccccaaa
     9061 cctgtgagta gtaatgagag gttttaagaa gatagtacat atcacacttt ttgaaaggtg
     9121 gtttacaggt atttcaaggc tattgtggga ttggaggaat acaatgaaca atttagaatt
     9181 tgcacttgaa atgaagaaca aacgtcttgc cagcggtctt tcacaaggag aacttgcaag
     9241 tcttacccat gtatcaagat atagtatcaa ccgctttgag aacggaaaag ctaacgccag
     9301 caaggaaaca cagaacatta tcctgcgttg tctgaattac tatatctgcg ataagccttt
     9361 ttatctgctc gttgattatc tgtctgtccg ttttccaacg actgacgcat tggaagttat
     9421 ccgaaaggtg cttggcatga aagcagatta ttttatccat tatgactatg ggtattatgg
     9481 ctataaggag cattatgctt acggggaaat caaggtcatg gcttctgatg atgaacacat
     9541 gggcgtattt ttagaattaa aaggggcagg ctcacgcaac atggaatatg tcttacaggc
     9601 acagaacagg gactggtatt cattcttaaa ccgctgtctt gactgtggcg gtgttatccg
     9661 acgttttgac ttggcaatca atgatatgtg cggtctgctg gatattcctg tgctatctga
     9721 aaaatacaga aatggtggtg cggaatgtcg ctgtaaaaac tatgaaaatg tacaaggtgg
     9781 aaaattaagc ggaaaaaacc gtaatttagc aagtaccctt tatatcggct caaaggcaag
     9841 cacaaaatat ttctgcctgt atgaaaaaca aaaggaacag gcaacgaaaa agaaacatac
     9901 cgatattatc aaccgttttg aaattcgtct gcgtgacaaa aaggcggtac aggcagttga
     9961 agaactgtta ttgacgtata accctcatgg gctggtgttt tatctcatta ccgattttgt
    10021 ggaatttcct gactatccat tgtgggagat attcatttcc catgacagtt taccttttga
    10081 aatgaaccct gtacctgtca atatggaacg cactctgcaa tggctggaaa gacaggtcat
    10141 gccgtcaatc gtgatgatag aggaaatcga caggctgaca ggttcaaact acatgaaaat
    10201 gattgatgaa tgtacccacc tttctgaaaa acaggaaatg cttgtggaac agatgtgtac
    10261 ggacatatca gacgtaatcg aaagtgaggg ggtgttttat gagtaataca caggatattc
    10321 ccgtatggga aaaatacacc cttaccattg aagaagcgtc aaagtatttc cgcattggag
    10381 aaaacaagtt aagacgattg gcagaggaaa acaaggacgc tggctggctc attatgaatg
    10441 gcaaccgcat acagattaaa cgccgacagt ttgaaaaggt tattgataaa ttggacgcaa
    10501 tctaatgcaa atgagccttg tatgtgttat gatgaacaca agtcatatca aggctctttc
    10561 caacaaggaa aggagcagac accatgaaag aaaaaagacg ggataacaaa ggtcgtatcc
    10621 tgcatactgg agagagccaa cgaacagacg gaaaatactt atataaatat gtagacgcat
    10681 tgggaaacac aaaatatgtg tatgcttgga gattgacacc cacagacccg acaccaaagg
    10741 gaaaacggga aaaaccctca cttcgagaac tggaacagca gataagacgg gatattgagg
    10801 acggtatcga cagcacaggc aagaaaatga cgctttgcca actctatgcc aaacagaacg
    10861 cacagaggac aaatgtgaag aaaagcacac agaaacaacg ggaacaactc atgcggttat
    10921 taaaagagga caagttaggt gctaggagca ttgatacgat aaaaccctct gacgctaaag
    10981 aatgggcgtt acgcatgaaa gacaaaggct tttcctacaa taccattaac aaccataaac
    11041 gctcgttaaa agcgtcattc tacatagcca tacaagatga ttatgtgagg aaaaaccctt
    11101 ttgatttcaa gctaagtgaa gtcatagaaa atgataccaa agagaaagtc gcattgacag
    11161 aggaacagga gcaagcctta ttgtcattta ttaagacgga caacgtgtat cacaagcatt
    11221 atgatgatgt gctgatactg ttaaagacag gacttcgtat ctcggaactg tgcggactga
    11281 cagtagccga cattgatttc aagaatgaag ttgtgattat cgaccaccag ttactaaaga
    11341 gtaaggaaca gggctattat attgaaacgc ctaagacgaa aagcgggata aggcaagtgc
    11401 cattaagcaa agaaacgata caggcatttc aacgggttat caacagccga ccaaagataa
    11461 agtcgataga ggtagacgga cacagcggtt ttgtgtttat caatccgaaa ggtaatccaa
    11521 aagttgccat tgattataac gccttattta tccgtatggt aaagaaatac aacaagcacc
    11581 acaaggacaa tcccttgcca catattacac cgcatacgct acgccataca ttctgcacaa
    11641 ggctggcaag caagaacatg aacccgaaag atttacagta tatcatgggg cattcaaaca
    11701 tcagtatcac aatgaactgg tacgctcatg cgtccataga taccgcaaaa tcagaggttc
    11761 agcgtctaat cgcatagaag tatttaccac gattttaacc acgattgaca gggaaaatat
    11821 aagaagatag acctagatat gcgaggttta ccacaaaagc aaaatgcccg tagagccgat
    11881 aaaataaggc tttgcggaca tttgagaaga tataaaaaga tagtcaaaaa gacatatata
    11941 atttataata attatgactc ttaattaaag taggtgccca tatgcttgtt tcttttagta
    12001 tggttataag attttttctg acaattttat tatcactgat attaacacct gtattcaaaa
    12061 tcatttcagt acaaacaggt atggtcgaca aaccaaatga aagaagaata aataaagttc
    12121 caatgccttc agcgggcgga ctgcctatct ttatttcatt tgttatatcg actttattct
    12181 tattccgtaa aattatccct caatcgtata ttgtaccgat cttgattgct tctttagtaa
    12241 tcatagtcac aggagtgctc gatgataaat atgagctgac acctaaacaa aaaagtatag
    12301 ggatcttgat tgcttctctt attatttatt ttgtagcaga tatacgtatt gattccttca
    12361 cgcttccttt tattggatat atccaactag gctggcttag ttttcccgta acgatttttt
    12421 ggatcttcgg tatcacgaat gcggtcaatc tgattgacgg tttggatggg ctggcggcag
    12481 ggatttcatt gatcggttta attacgatag gaatcattgg atattttttc ctccatgctt
    12541 ctacagtgta tattccagtt gttattttct gtcttgtagc aagtattatc ggtttttttc
    12601 cttacaattt ttatccggca aagatttatt taggcgatac aggagctcta ttcctagggt
    12661 ttatgatggc cgtcctttca ctacaagggc tgaagaacgt gacttttgtt tcatcgattt
    12721 ctttgctgat cgtcatggga gtgccggtaa cagacacgtt ttttgctatc attaggagaa
    12781 aagcaaaccg tgtttctttt tctacagcag ataaaaaaca tcttcatcac cgactaatca
    12841 gtttaggctt tactcataaa ggtgctgtcc tgacgattta tgcgatggct ttgatgtttt
    12901 ctttcacagc tatggtcatg aattatactg gaagaatcgg aacgatcata ttgattattg
    12961 ccatgttgtt tgctgcaatt ttattatttg aattgattgg tctgatcaat gagaaacatc
    13021 agtttatttt aaaaacattg cgatttttag ggaataaaga gtaccgtacg caagtaaaac
    13081 agaaatattt gaagaaatgg aaccgtcata tagatgaata acaaattaaa ccagccgatc
    13141 cttattagta ttgtgacggc aaacagtgat aaaatttttc ggacactaga taattttatt
    13201 tcaactgtaa aagatgaaac agcagtaaaa atccgaattt ttgacaacaa ttcacttccc
    13261 gagtacaaaa aaagactaac agagtatagg aaatatccct acatcgatat ctattttcat
    13321 gatgaaaatt ccggatttgg ttatggacat aatcacaatc tgatagctag cgattctcgc
    13381 tatggcatta tttgtaaccc agatatttta gtggatgaag agacagttac agcattggtc
    13441 ttgttattga aagaacatcc ggaatgtgcg atgttagcac ctaagattct taatgaagat
    13501 ggaacaactc agcacctcat ccgtgagcag ctggctgttt ttgattacgt tttgcgcttt
    13561 gtgcctttca aatgggtcaa aaaaaagttt gacaaacgac tggctgtgtt tgaatgccga
    13621 ggattgccta ctgatgctaa tagttatgta cggatgatct caggtagttt tatggtagct
    13681 gatattgata aatttaaaga gataaagggg tttgatgagc gtttcttcat gtactttgaa
    13741 gacaacgact tgtgtttgag ttttgaaaaa gcaggttaca agttattgta cacacccttt
    13801 tatgcagtta tccattttta cgggaagggt gcgcatcgaa atgcaaaact gtttcgcgtg
    13861 tttttgactt ctatgatgaa atttttcaat aagtgggggt ggcgtttttt ctgatgaaac
    13921 cagaaatatt agtagtcgtt gtgctttatc agcaactatt cagtcaatct ccagcttatg
    13981 gaccattaag caaagcactt agcgaaaagc aaattcagct tattatttac gataatagtc
    14041 ctcaaaggca gcaaaatgag ctgtttgaaa aagaaaatat cgtttatcat catgatccgc
    14101 aaaatcctgg tttagcggtg gcttataatt ttgcgttgtc tcaagcagat gaaggaacac
    14161 gttgtctcgt cactctggat caggatacga ggctagtcga cgattatttt gaactattgc
    14221 gtaaagtaac ctttacagat gaatgtgttg ctgcagttcc gatgattttt tctgggagcc
    14281 gacaagtttc tcccctatat tcagatcgtt atatcaatcg tacagctcaa gcagtagaag
    14341 ttgaaggccc aacagctgaa cgaatcatgg caatcaattc aggtgttgcc tggtctgtca
    14401 aatttctaaa aaagattggc gggtttaatc ctgctttttc tttagatttt ttggatcatt
    14461 ggctgttttg gaaagtggat cagttggaaa aaactgtgga gatccttcct gtacgaatgg
    14521 aacatgatct ttcggtttta gactatgaaa aagtttcaag taatcgatac cgttctattt
    14581 tacaagcaga aaatcgattt tatcatgaat atgatcaaag gcatttatcc agtcaccgac
    14641 gacaattatt gttaagaaca gctaaacagt tcttgaccgt caaaaaccgg catatctggc
    14701 ggatgacttt gcgctcatat gttaagaatt ggaaggtgtg aattcgtgcg ttcggtttgt
    14761 atagctacct ttaatggagg cagatattta agagagcagt tagatagtat tttatctcag
    14821 ctttcagcag aagatgaagt agtcatttct gatgatgggt cagtagatga tacatgggat
    14881 atattaactg aatacgcaga aaaagataag cgaatccagc ttttttcggg gcctcgtcaa
    14941 ggattgatcg ctaattttgg ttatgcgatc cagcagacga aaggagatct aatctttttg
    15001 gcagaccaag atgatgtttg gttggagaca aaagtgaaaa agatcactga ctattttgag
    15061 cagaatccgg atcagctagt agtagtttct gatttaatca ttgtggacag cgagctgcaa
    15121 gagatccatg attcgtattt ttcgtttcga aattccaaag aaggatggct taataatgtg
    15181 ataagaagtc actatattgg tgctggtatg gctttccggt cttctttaaa acccgatatt
    15241 ttgccgatcc cgtcagaagt gccgatgcat gatatgtgga ttggtttgct gggaggaaag
    15301 aagactgggt tcctaagaga accgttaact ctgtaccgaa gacatgattt aaacgcgagt
    15361 gagattgaaa cacattctaa attacggcaa aaaatttctt ggcgtgttca tctgattacg
    15421 gcgttgatca aacgaaaatg gtttaaacgt tgataaaaga tgtttaaatc cttaatattt
    15481 ccatgacaaa tataacaatt gatgagataa taacaaagtg aaatttgaaa tcaaaaagga
    15541 gagcagatat ccatgaaggg aatcattctt gctgggggca gcggaacacg tctgtaccct
    15601 ttaacaaagg caacatcgaa acaattgatg ccgatttatg acaaaccaat gatttattat
    15661 ccaatgtcta ctctgatgtt ggcgggaatc aaagaaattc tgattatttc aacgccacaa
    15721 gatacaccac gtttcaagga attatttgga aacggaaatg atttaggact gcagatcgaa
    15781 tatgcagtac aagaaagtcc agatggattg gcacaagcgt ttatcattgg agaagaattt
    15841 attggagatg atagtgtctg cttggtatta ggggacaata tttactatgg tggcggtctg
    15901 tctaaaatgt tgcaacgagc agcttcaaaa gatacaggcg cgacagtatt tggctatcat
    15961 gtcaatgatc cagaacgctt tggtgtagta gaatttgatg agaatatgca agctttgtcg
    16021 attgaagaaa agcctgctca gccaaaatca aattacgctg taactggcct ttatttttat
    16081 gacaatgagg taatttctat cgctaaaggt atcaaacctt cagaacgtgg agaactagag
    16141 attacggatg tcaataaagc atatttggat aaaggaaaac tatccgtaga acttatggga
    16201 cgcggatttg cttggcttga tacaggaaca catgaatcat tgcttgaagc atctaccttt
    16261 atcgaaacaa ttgaaaaacg tcagaactta aaagtggctt gtttggaaga aattgcttac
    16321 cgtatgggct acatcgataa ggaacaattg ctggcccttg cacagccatt gaaaaaaaat
    16381 caatacggtc aatatttatt gaatttggcc gctgaataag gagtccttac agatgaaagt
    16441 aacagataca aaattaacag atgtcaaaat cgtagaaatg gacgtctttg gcgatcatcg
    16501 cggtttcttc acagaaagtt attcaaaagc aaaatttgca gaacatggat tgaaatatga
    16561 ctttgttcaa gacaaccatt cactatcagc tgaagctggt gtccttcggg ggcttcattt
    16621 ccaaaaagga gaagctgcac agacaaaatt gattcgggta gtcactggag cagttttaga
    16681 tgtagtagtg gatatccgca aaggtagccc gacttatggt caatgggacg gatttatctt
    16741 atctgaacat aatcatcgac agttgcttgt acctaaagga tatgcccatg gattcgttac
    16801 tttgacacca aatgtgaact tcctttataa gtgtgataat tactataatg cagaagcaga
    16861 tgggggcatc gcatttgatg atccagattt agcgattgat tggccaattg atccatcaag
    16921 agcgattatg tcggaaaaag atcaccgtca tccgacatta aaagaatttg aagcagaaaa
    16981 tccatttgtt tacggagaaa tctaagaatt aaggagaaat tttcttatga aaaacatcat
    17041 tgttaccgga ggtgccggat tcatcggctc taatttcgtt cattacgtgg taaacaatca
    17101 tccagaagtg catgtcactg ttttggataa actgacttat gcaggaaaca aagagaactt
    17161 ggctggactt cctagcgatc gcgtagaatt ggtcgtagga gatgttgcag atgcagaatt
    17221 agtggaccgt ctagtaaaag aagcggacgc agttgttcat tacgcggcag aatcccataa
    17281 cgataattca ttaaaagatc ctttcccatt tgtacaaacg aatatcattg gtacgtatac
    17341 acttttagaa gcttgccgca agtatgatgt acgctatcat cacgtatcta ctgacgaggt
    17401 ttacggcgat cttccattac gtgaagacct gccaggacat ggggaaggcg aaggagaaaa
    17461 attcactgcg gaaacaccat ataatccttc aagtccatat tcttctacaa aagctggttc
    17521 agatctgtta gtaaaagcat gggtgcgttc ttttggctta cgtgcaacca tttcaaactg
    17581 ttcaaacaac tatggtcctt atcagcatat tgaaaaattt attcctcgcc aagtaacgaa
    17641 tatcttaagc ggtattcgtc caaaattata tggcgaagga aagaatgttc gtgactggat
    17701 ccatacgaat gatcattctt cagcagtgtg gctgattttg acgaaaggca gaattggcga
    17761 aacctatctg atcggtgcag acggtgaaga agataataag accgtgatgg aattgatctt
    17821 agaaatgatg ggtcaaccaa aagatgcgta cgaccatgta aacgaccgtg caggacacga
    17881 cttgcgttat gcaatcgatt cgacaaaatt acgggaagag ttaggatgga agcctgagtt
    17941 tacgaacttc cgtgatgggt tggctgacac gatcaaatgg tacgaagaac atgaagactg
    18001 gtggaaaaaa gaaaaagagg ccgttgaagc agcatatgcc aaaaatggac aataatacag
    18061 agaaaatgtc actgtattaa tggaaaaaca catgtgaggc aggcgctcgc ctgtctcttt
    18121 tttaaaataa aaatcaagga gcggataatc atatgttttt attaactgga ggaaatgggc
    18181 aactaggtac agaattgcgc catttattag atgaaaaaaa tctgcaatat gtttcaacag
    18241 atgcaaaaga cttggatatc acagatgccg agaaaacaat ggcttacatc acagaattaa
    18301 aacctgatgt tattttccat tgtgcagctt acacagcagt agataaagca gaagaagaag
    18361 caaaagaatt agatgagaag atcaatgttg atggtacaag aaatgtagca cttgcagcaa
    18421 aagctgtgaa tgctcaattc gtctatatca gtacagacta tgttttcgat ggaaaaaaca
    18481 aaaatgtaga atacgaagta gacgaccaaa cgaatccact aaatgaatat ggtcgtacga
    18541 aattattagg cgaaaaagca gtagaagaga ttttagaaga ctattatatc atacgaactt
    18601 cttgggtttt cgggatctat ggacacaatt tcgtcttcac gatgcaacgc ctagcggaaa
    18661 cccgcgacaa actgactgta gtaaatgacc agtttgggcg accaacttgg acacgtactt
    18721 tggcagaatt tatggtatat gtcatcgaag aaaaagcacc atttggtatt tatcatttgt
    18781 cgaacgaaaa tagctgttct tggtatgaat tcgcaaaaga aatattgaaa gatacagatg
    18841 tagaagttgc acctgttacg tcagaagaat ttccgcaaaa agcaacacgt ccgcagtatt
    18901 cagtcatgag cctgaaaaag acagaagagt taggatttgt cataccaact tggcaagaag
    18961 cacttgcgca aatgctggaa gctgccaaaa aaatgaataa gtaatttcct tttatcaaat
    19021 agaatttgga gcatgatatg gaaaaacaaa caagaagtgc acgacgaaaa gaaaagccaa
    19081 aagcgaacca ggcagattcg aatttggtgc ttgacctgtt tctaaaactc cgctatctta
    19141 ttggcgtttt agtcatcgtg gtcatcgtta cttttaattt aaacggaagt tcacttggtg
    19201 tttgggataa atatgtgtcg caaagagacg atgggaaaaa aactgatgtg atttttggac
    19261 agaatcggga agtgcggtca gacgaatggc tggtgcagac acctttttac ctctcacaag
    19321 ctgaagagga ctttccgttg gtgaacgagg attattcatt aaacggacaa aacatgatca
    19381 ttgcgtataa ttctcctgta aaggatatta cggttatcgg aaaaccattc aactggggat
    19441 tctttttcct cggaagagat cgaggacttt ccttttattg ggcgatgaaa ttagtcgtca
    19501 tggtcttgct tggattcgaa gtactgatga tattaacgaa gagaaaaaaa gctctatcgc
    19561 taatcggtgc atttgcgctg acattttctc cagcagtcca gtggtggttc atgcaacatg
    19621 tgggcgattt gattttcttt actttgggac tgatgactgc tttttatcat tatttctaca
    19681 atcatgataa aaaatggcta cgaacgttga tgatgctttt ggtggttatt ttcggtattg
    19741 ggtttatttt agtgatttac ccagcccatc aagtgatgct ggcgtacttg ctgatttttt
    19801 attttgttgg cctgcttatt tactatagca agaaagtttc atgggatctg ttggatgtag
    19861 tgttgattgg aggggcagtt ttatttattg gcggagtcat ggttcatttc tggctaacgt
    19921 caaaagacgc attgttagct tctttgaata ccttatatcc aggaaaacgg gtaagtactg
    19981 gaggaaagtg gacgattggc gaattttttt ctttccttac aaattggaaa attccttttg
    20041 aagatatcaa ctattcgaat aactctgaag tggccctgtt ctatcacttt tttccaactg
    20101 tattcctagc aagtccattt gtgttatttg gcaaaaaaga tagcgaacaa aagttactgg
    20161 gacgtatttt gatgattttt tgtctgtttt ctatcttttg gattaccgtt gggttgccaa
    20221 aatggctagc agaaatcact ctgctgtctt atgttcctcc attaagagcc atccttactt
    20281 ttagttttgc ggcttgttta ttatcgatct ggtttatcgc ttatatttgg agagaagatg
    20341 ttattcctat ttggtataaa ttcattttgt tggcagtaaa tgcatggtct tatttctatg
    20401 cgattacgca ttcgaaaatg gataattatt tttcggattt tgaaaccatc gcagttgctg
    20461 tgttgggaac agtgatttta gcttttgcat tatttggctg gagacgcttg ttttacctcg
    20521 cttttgccgc cttagttatc gtatctggct ttttcgtcaa tccagtcgta gaaggtacag
    20581 gagcgatttt tgaaaaaaca ctggcaaaag aaatccaaaa aatcgatcaa caagatcctg
    20641 gtaaagtttg gttgtctgaa gatgaattat ataacttcac cccaacattg ggagtgaaat
    20701 ccttcaatac agtacgcttt tatccagata tagctgcatg gaagaaaatc gatccgaaag
    20761 aagaatacga gaagtattat aatcggtatg ctcatacaag agcttttatc gctaaggaag
    20821 atacaaagtt cattttagat cgtccagata tgttttcggt cacgttgaat tttgaagacg
    20881 cagaaaaatt agggatcgac tatgtgatca gtaaacgacc attaactgat tacaaccaat
    20941 tatatgaagc gcagttcacg cagctatatg gaccggataa agacggttat atgattttta
    21001 aagtagaata tccggattat ccagatgtac cacaaacaca aactcaggaa aatcagctag
    21061 tcgtacagta ataggctagc tgagaataat cctgaaatgt tagtagaaag gagagtggag
    21121 ataattcaag caatcgtaca aaaatttgtc aacaaaatga gtgtcggttt cttgcttttg
    21181 ttactgacgc tagtcttttt tgtttggaca gcagggttag gttttccagc aactttgttt
    21241 atatataaca atagttcatt acttatcgct tttagtgtgg ctattttgct cattttaaat
    21301 gtttataaag caaaaggcgt cgattttctt tatctaggtg ttgcgcttgc ccttttcatt
    21361 ttcttttctt actttcggga attaagaaat gagtctttat ttggagactt actgtttcct
    21421 ttgattattt tattttgttt agtaattaaa tggatcgagt ggacaaaatg ggatcgcggt
    21481 atttatctga ttgtcttttc ggtcttcctc ggaatcacgt tatatcgtgt atttacagag
    21541 atccaagtac cagaaggaca aagcatctgg gctccaggca attcgctttc tgatatttgg
    21601 atcaatacga atataatcgg aagttctttg atgactcttg ctttattgat cagtggattt
    21661 gccagttctt ttgaacgatg gtatgtacga atcatcggtg cagtagcagt tgttgcagct
    21721 tttctcggga tttgggtctg ccaatctaga ggtgcattag tcgcgttgat tgtttttgcg
    21781 atattggatc ttttacctaa atcgttgatg cgtgtcattc gtgcgccatt tattgcttac
    21841 acggttacga ttcttttagc tttgccgatt tcttatctgg cggctgtctc tgaaaaagtc
    21901 aatttgttta ccggtcgaga agatatttgg cataaattct atcagacgct aggagaaaaa
    21961 tctgaacaaa ttttactagg aatgaaaaca tttatcttcc aacgaggaaa ccaattttta
    22021 ggaaaccaca atagttataa ttctattttg aatatctatg gattgatagg atttgggatt
    22081 gctgctttgc tgcttatcct ttttattggt cgcttaacgt tgaaagcaga tttatccaac
    22141 gggcagatga cttttatctg ggcctttttt gcggtgatga tgcagtcatt tatggaggat
    22201 acattgactt catacccatg ggttccgatt atttatatcc tgttggctat ggccgttcat
    22261 cgatatgatg aaccagaagt tgcggaggaa ttctatgtta tggaagaggc atatgacgat
    22321 atgacttatg atgatacatc ttatgaggaa caaccagata gcgctcattc ttccaggatc
    22381 caacgctatc attgataggc acaaaatacg agagaggctg tgacaaccgt cgcagccttt
    22441 tttggtttat tgcaattgtc tagcatcttc tgtaaaatag aaacgttaga gaaaatcttg
    22501 tatcatagaa aattaagaaa gaaataagaa cgcagctcgg taccaaaaat atggtaaaat
    22561 ggcacttgac tgtaattcac tgaaaatcgc ttggaggaac acaaatgttt aaagatttgt
    22621 atttatttat gaaggacatt tatcagaaca gaaaattatt gctacagttt tcgatcaatg
    22681 acttcaaatc aagatatgca ggatcgtttt taggaatctt atgggcgttt atcaatccgc
    22741 tatttactgt attgatttat tggctggtat ttggtgttgg actgaaagca caaatgatcg
    22801 atgcaaaata cccatttatc gtatatttag ttaccgggat gattccctgg ttcttcttct
    22861 cagatgcatt tgcatcaact acggttgttt ttcgggaata tacttattta gtaaagaaag
    22921 tcgtattcaa tattcgtatc ttgcccacga cgaaaatcct atccaatctg tacacccact
    22981 tattcttcat tctgattggc atagctgtcg cgcttataaa tggtatatat ccttcagcaa
    23041 tgtctttaca gctgatttat tatttatttt gcatgtgtgc tttcttgaca ggattgactt
    23101 ggctgacggc atcgatccaa ccatttttac ctgatatcat gcaattaatt acgatcgtgc
    23161 tgcagttgat catgtggaca ttaccgatat tatggagccc taatcagttt gattcaggtc
    23221 ttgtaagcat attgaaatta aatccgctgt actatgttgt tcaaggttat cgtgagtcat
    23281 ttttaagtga agcttggttc tgggagcatg gaacatatac tttgtatttc tgggttttca
    23341 cgttagtaat gttcgtaatc ggctctgcag tgttccgtag attgaaacca catttttcag
    23401 atgtgctgta aggagaatag ctatgacaga atatgcaatt agactaaaag atatcacaaa
    23461 atcttataat atgtacgcaa aaccttcgga tcgatttcgt gaagccctca atccttttaa
    23521 gaaatcctat catgatgtat tttatgcgtt gaaaaacgtg aatgtagaaa taaaaaaagg
    23581 tgagatgatc ggtttcgtgg gagaaaacgg atcgggaaaa tctacaatgt tgaaaatcat
    23641 tacgggagta ctgacaccaa catccggcac gatggaaatc gaaggaaaaa tctcagcttt
    23701 gctagaacta ggatcaggat tcaatcctga gtattctggc tatgaaaata tctatttaaa
    23761 tggaatggtt ctaggatttt caagagaaga agtcgatgaa atggtcgatg atatcattga
    23821 atttgctgac atcggagacc atatttatca acctgtaaaa acttattcaa gcgggatgtt
    23881 cgttcgtcta gcttttgctg tagcaatcaa tgtgaatccc gatattttga ttgtggatga
    23941 agcattggca gtaggcgatc ttgaatttca actaaaatgt atggaaaaat ttacagaaat
    24001 caagaactcg ggaaagacga ttttattcgt ttctcatgat atcagttcga ttcgtcgttt
    24061 ttgtgatcgt tcctattggt tgaaaaacgg agaagtcgtc gaatatggcg atacgatgga
    24121 agtaacgacg aattatgaaa actttttaaa gaaaaaatca gttaaaacag tggatcggaa
    24181 taaaaaccaa gtagaacggt tcgccgctcc agatatcgtc gacgtgacga aagcggaatt
    24241 gttggataaa gacaaaaatc cggtggatat gctggaacaa ggagaaaaac tatacgttaa
    24301 agtaacttat gaagtaaaag atgatacaat caaaaatccg gttttaggaa ttgcgctacg
    24361 aacagtcgac aatttttatg tatgcggact taatactcta ctagatggta tcaagattcc
    24421 ttggaaaaaa ggagagaata tcttttatct ggagtatgaa aagttaggtt tgttagctgg
    24481 tgaatattat tttgacgttg cggtctttga agaaaatgca acggttcctt tggtatataa
    24541 gacaaagtac atgaacttgt ttgtcagcgg ttcttatatc ggagaaggca tcgtggtctt
    24601 agaccataaa tgggaagaag ggactcatag caatgaaata tgattttgaa atggacctag
    24661 atgaacaaag cagtgtggga aaaattgccg cacagatcaa accaggaagt aaagttttag
    24721 agtttggtcc cggaaacggc cgattaacga aacatttaat cggagcaaaa caatgtgaag
    24781 tgagcattgt tgagttagat aaggaattgt tcgattttgt cagcgaattt gctcaagatg
    24841 gattttatgg tgatatcgaa agttttgagt gggcaaacta ttatgctgga cagacatttg
    24901 attacgtctt gtttgcggat gttttagaac atttggtaga tcctggaaaa acattgaaga
    24961 aagtcagaga atttttgaat gaagaaggag agatcctgat tacattccct aacttggcgc
    25021 ataattctgt catgatcgat ttgttcaata accaattgcc gtgggcttct tatggtctcc
    25081 tagatgaaac ccataattct ttttatactc atgatggctt ccaaaaagtt tttgaaaaag
    25141 cgggattatt cattaatatt gaagattatt tgtacttagc tgtaggtgat acagaattaa
    25201 aatcaactta tgaagaattg ccggaagctg tacgctatga tttcaaaatg cgaccatttg
    25261 gtgaagtcta ccaatacttt ttctcattga tgaaacatcc agtagcacaa agttccattg
    25321 cagagccaca aaattctaat tatgtaaaag tgttagaagt aacccagcaa acgaaacaag
    25381 atgaaacaat ccaacaaata ccattcaata atttcacagg ggaaaatgag acactaagtt
    25441 tccccgtatc agaaacaaca gaaagaatgg tgtttcgctt cgcgcaacaa cctagcttta
    25501 tcgaattcag cgcagaagct gccggagaaa aactaacatt tatcgattcg aatgctgtag
    25561 tcaaaacagt aaatgattgt tatttgtttg atgggaaaga attaccagag ttcgttctaa
    25621 cggatatttc tgggaaagaa gtgactatcc attgtcacta tcgctttatc ggggaattga
    25681 caccaacaat gaaagaattg ttggaaacga ttcgtcccat ggctgaagtc acaaagcagc
    25741 tttctgagaa aaatgacgaa ttagaaagag aaaatcatca tcttcttgag gaaaatacaa
    25801 gactagacca tacgttaaaa acaaccacaa atcgctattg cacattgttg gaaagtgatg
    25861 aatggacaat aaaacataga ctaggacgac gtaagaaaga aacttcgaaa aaaatccaag
    25921 aaaaagaact ttctatatgt attgacgaga aaatctggga tgcagaaaca aaaatattaa
    25981 aaatcatcgg atggggaatc gctaattcgg atcgccagcc cttgtcctat aagttatcag
    26041 ctgaccaatc gccatttttc gaagcaattc ctgtttcacg agaagaagtc aatcaagcag
    26101 aacagctcgc aaaaggaaca gaagcgggat ttgagttacg aatcctttgc gagcaagaac
    26161 gttcattctt agtggaagca gtagctcaaa atggccaatc atggatcatt gaaatgtaaa
    26221 taatgattaa cttataaaga taaggagtaa acgaatcgtg caaaaaaaag aaattgccgt
    26281 atttatcgat caaatcactc gtgaacgggc cactggcgat ttgcttattg tgggctgggc
    26341 aattgatgaa gtgaccaaag aaatccctac gataaaggta gaaaaagaaa atgtgattgc
    26401 tgaagcaaca catgtcgtaa gattggatat caatcattta tataatcttg atgttaagac
    26461 ccaaagcggt tttaaggtac gtttatcagg gaaaatgaga ggaaaagcca tcttagactt
    26521 ccaaacagcg agacatcaaa atggcatagc tgtgaaatta aacggtaaat acccttatga
    26581 tgacggcatt gaatcttcat gggaaagaaa aaaaagatta ctgaaaaaag ggataaatta
    26641 tgcaaggact catggcgtaa aaaaagcgat ccgtcgggtc aaattggaat tgaagccagg
    26701 atcgatcgac tatgcagagt ggatcagtcg tcatgagaaa ccagatttga aagagcaaag
    26761 gaaagaagca caaggatttg cgtaccgtcc attgatttcc atacttatgc ctgtctataa
    26821 cgttgaaatc aaatggctcg aaaaatgcat tgattcggta ctggatcaaa cgtatgatca
    26881 ttgggaacta tgtatcagtg atgatgcttc tactgatcca gctatccgaa agtgtctgga
    26941 atcctatcaa gcaaaagatg atagaatcaa agtcgttttc cgaaaagaaa atggacacat
    27001 cagtctggca actaattctg cattggaaat agcagaagga gaatttatag cactcttaga
    27061 taatgatgat gaattaccgc catttgcatt atatgaagtg gcaaaagtgc taaacgtaca
    27121 tccagaactg gatgtgatct acagtgacga agataaaatc gatgcagatg gcaatcgctt
    27181 tgatccgcat ttcaaagcag actggtcgcc tgatacattg atgggaaata attatatctc
    27241 tcacttaggc gtatatcgaa caagcattgt taaagaactt ggcggtttcc gtaaaggcta
    27301 tgaaggttct caagattatg atttggtcct tcgtgtgaca gaacaaatcc ctgcagatca
    27361 tatttaccac attgaccgag tcttgtatca ttggcggacg atcccaggat caactgcaag
    27421 taatggcgaa gccaaaagtt atatctatga ttccggagtg aaagcattga cagatgccct
    27481 gtctagaaga aacatcaaag gaagcgtacg tcctggcaga atttctggat tttatgagat
    27541 tgcttatgac gtcttgcaag aggatttggt cagtgtgatc attccaacga agaatggcta
    27601 tgaagatcta aaaacttgtg tggattcgat catcgaaaaa acgtcttatt caaattatga
    27661 aatcattatt gcggataacg gaagtacaga tccaaaaatg caagaattat ttgcagaata
    27721 caagcatcag ctgaaagacc gctttatcgt agaattgatt gacattccat tcaattattc
    27781 tcgaattaac aatttagcag cagaaaaagc aaacggcaaa tactttttat tcttgaataa
    27841 cgatacagaa gtgattgagc cagattggat gacggtgatg gtttcttatg cacagtttga
    27901 tcgaatcggc tgtgtaggag caaaactgtt ttatccagat gatacaacgc agcatgcagg
    27961 agtattatta ggaatcggtg gtgttgcagg gcatgcattg aataactatg atcgaacaca
    28021 ttgtggttat ttcggccgat tggtcattga cgtcaattac ttagcagtca ctgcagcttg
    28081 tatgatggtc aaggcagctg acttcaatgc tgttaacggg tttgatgaaa cattagaagt
    28141 agcattcaac gatgttgact tgtgcttgaa agtttatgaa ctgggtcgtt acaatgtcta
    28201 tgcacatcaa gcagaattgt accatttcga atctaaatca agaggttatg aagatactcc
    28261 agaaaaacaa agacgttttg ctggtgaaat caaaaaaatg caagataaat ggccagcata
    28321 tattgcgcat gatccatttt acaatgataa tttaacaaaa gaaggaatcg gcgacttttc
    28381 gttgagacca gattaaacta taataaaaag ctgttatgtt gtgattcgct cgcacataac
    28441 ggctttttat agttttttgt caaaaaaagg cagaaggtgc cgactcaaaa aaataagtcg
    28501 aggttgggac agaagtgttt aactccgaga aataagaaga aattcacgaa aattgctttt
    28561 caaatttttg tgaatttcgg cttatttaag aagaagttgc ttctgctccc accgtttatt
    28621 cgtttttaaa gaatgagaca aaagtgtttc ttacttttgt cccacgctct tattcatgct
    28681 cagagcgcca atagatacaa aatcatagcc aaagtttcac gaaccctagc tgtcaaagaa
    28741 tcgatatttt attttaatat aggctatttt aaaataaatg gtttaaggta ttcctctaca
    28801 aaagccactc tatcaattat catgggttta aaataagaag tgatggagat aaccagattg
    28861 ttcttagcgt caatataaag aacatttcca ctattaccaa ttgctgaata tatttcgttc
    28921 tcagaatcta atacccacca taaatagcca tatctcatat tttgtaagtc ttctaaagca
    28981 ctggttctag gtttgaacat ctcgtttatc cacatgggtg gtacgatttg ttttccttta
    29041 tacatccctt tatttaggca taatacacca atttttgcca gatcacttgc cgataaacac
    29101 aaaccatatc ctgccgtccc gatatttagt ggatcacaaa accagacatt ggttttagga
    29161 gacttatcca ttgtaaactg cttatgttct tcagctgttt cagcataata attgacatgg
    29221 tttggtatcc ctataggatc aaatagatac ttattggcaa aatcaacagt tgttagctta
    29281 cttgtctgat acaacaagcc agttaatatg tgtaaacaga cagtttgata gttgaattcg
    29341 ccggttatac cttttcttcc tcccaataaa tctagtgatg tttttgtcca atcttcactt
    29401 gaacagactt ttgtccatgg atcgccttta catttgtagg gtgctttcat tgttagcaag
    29461 tgcttgattg taatagcgta aatagttttc tccccgcgtt tcactttata ctctggaaaa
    29521 taatctaata ctttatcatc gatacttttg attaatcctt gctctaaagc aatgccaatc
    29581 agcaaagata caatactttt cgttgctgac atgatatgac aagtatcgtc ttttttataa
    29641 ccattccatt catctgtata aacttctacc ccatccttat atgcgacaat ttgacatata
    29701 tttggttgtc gaaaaccaat aaaatcatgc aactcttgtt tattcataag atattacctc
    29761 actttcttct ataagcataa tgtcattaaa aatcgatttc aattttttcg attcttcacg
    29821 taatacaggt attcttatgg actagacagc gctttgggaa gatggattct ctgaaaaata
    29881 taaaggttca ctttatgagt ggataaaaaa agcagcaaat acttcgactt ctttaattta
    29941 ccaacattag tgaaaatcga ttcatctgga gatttgtaat ttagagtcct tgtcttgatt
    30001 agaggtgtat aaagcttttt attagacatt tttaaattcc attacaattt gcttataaac
    30061 taggttttta aaggtgacta tggtaagata atagagatat tattttgtga ttaggagtgt
    30121 atatatgaat aaaaatggag aatggagtgc tgcacgacgg atattcatta tattaatgga
    30181 tgttattgta tacaatgcag caatatatag tagtttctta ctgaagtttc gtggagagat
    30241 cccattacga aatttagaaa ctttccaaca ctcagcaatt attatttcag tgatttttat
    30301 tgcgttgaac attttgttgg gtgcatatgt tttttataat cgaatgatca gtgacatcgt
    30361 gtttgtcaca gtcatcggtc aggtattgat gacactaggg atcatggtag tgacttttgc
    30421 gggccgctgg tttgcttttc cacgtcttgt tatcttactt tcatttgttc tcggtacgct
    30481 tttcttaagt atctatcgta ttctcgtata taaactttat ttacgcgtaa gtcgagataa
    30541 aaaggtcgtc attattgggt tagaaaagga tgtcgcacca gcaatccaaa attttggttc
    30601 aaagaaaaac aacaaacata aagtcgaagc agtcattctt gataactatt atgcaaacat
    30661 caaaaatatg attaaagaca tcgatattgt ctatcttgct tctcatatcg aagaaactga
    30721 aaaaatcaaa atctatcaat tagttactaa aaatgaaaaa aaattgtttt tgaatacaac
    30781 atttgaaaac ttgacattga tcaatccaaa tattatgaat ttcgaagatg aaagtattat
    30841 tgaagcatct ggatttagaa tccaacctga atatgaacta ttcaaacgtt tgtttgatat
    30901 catcgtttca cttgttttat tagttattgc ttcaccattt atgttattca cagcaatttt
    30961 agtcaaagtg acatcaccgg gaccaatcat ctataaacaa gtgcggatca caaaaaatca
    31021 aaaggaattt tcaatctata aattccgctc gatgaccgcc acagccgaag caaaatctgg
    31081 accagtttta gctaagagca atgatgcacg agtaacgcct gtaggtaaat ttattcgagc
    31141 tgtccgcttt gatgaattac cacaaatctt caatgtgctg aaaggcgata tgtcgatcgt
    31201 aggaccacgt cctgaacgtc ctttcttcgt cgatcagttc aatgcagaaa acccttatta
    31261 ctacttacgg cataatgttc gtgctggtat cactgggtat gcacaagtct atggaaaata
    31321 tgtctctgat tacaacagta aattacgttt tgatttactt tatatcaaaa aatattcatt
    31381 gatgcttgat ttaaagatct tgctgcaaac catcaagatc ctatttgata aaatgtcctc
    31441 tcaaggactt gaagaagacg aaaatgtgat ctcattggca gaaattgctt ttccgaatga
    31501 aaaaatcttt cgctagttgg gaggcgtaaa aatgaacaat ccgaaattca gcataatcgt
    31561 accagtatac aatgcagaag caactattgg tcgaacgatt gatattctaa aagaattgga
    31621 ttatgaagag tacgaagtcg ttttagtaaa tgatggatca acagatcaaa cacaggaaat
    31681 cattcaagaa ctgattgaaa atgatgaacg ttttgaattg attactacga ccaatcaagg
    31741 gcccggatta gcaagaaacg aaggaataag acagtcaaaa ggagaatatc tcttattctt
    31801 cgatgcagat gacacgccag taaaaacgat cttgtcagat tatgatcatt tgctagaaaa
    31861 gagtccaaaa gcggatcttg ttgttagttc gtttgttttt cgtacaatgg acgagggaag
    31921 aatcgtttcc gaaaaagaaa acttagttac agaatgtcac tatctaactc acgaagagtt
    31981 tataaaagac atgtatcagt taatgaatga acagttgatg tatgttgtat ggaacaaatg
    32041 ctatcgtagc gatattctga aaaataacca aattctattt aaaacttata atagttgtga
    32101 ggatcgaata tttaacttac attattatga atactgtcat caagtgatca tgaacccaaa
    32161 agtagaatat atttatgaat ttgaaggtgg gaaggggatc actaatcaat accgacctaa
    32221 caagttcgaa acatttaaag aattctattc attagcaaat actgtaacag acgatattaa
    32281 taaagacggt atggcggcgc ttcttttaaa agggacaact tcagttattt tttctattta
    32341 tagtacctct gcaagaactt caaaagagaa gaaagacgaa gcaaagcaga tattgagtga
    32401 tccagtgatc cgagaagcca agcaaattgc taagacggat tcttcagcaa aaaaaataac
    32461 aaagttgctt tacaatatgc cagctccact atttttatct gctgtaaaag ttggaagctt
    32521 cgttgaagtg aaaatgccag ggttaatggc tgctttgaag cgagtatatt agttaatgga
    32581 ggaaaatata atgaaaagaa ttttgcattt tcagggacga atgggtttag gtggagcaga
    32641 gtctttcatg atgaatttat atcgtaaaat tgatcgtaca aactatcaat ttgatttttt
    32701 gatttatgaa gattatgcag atgttcaaga ctatcattca gagattgaaa gattaggagg
    32761 ccgta
//
LOCUS       DAZKKZ010000033        29981 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.033, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000033 DAZKKZ010000000
VERSION     DAZKKZ010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 29981)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29981)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29981
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.033"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            151..489
                     /locus_tag="ACG8LA_001582"
     CDS             151..489
                     /locus_tag="ACG8LA_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0203886.1"
                     /translation="MPDYKQKAGYSFCSDKFQLGKFTKLAGEEVSTVRIKECPLQIET
                     LVQRISTRQDFAIVEREIVAIFVEEGILHDPTHINVDKWQPLIYKFREYTTANQSLTL
                     NFRFQEFKES"
     gene            complement(694..1256)
                     /locus_tag="ACG8LA_001583"
                     /pseudo
     CDS             complement(694..1256)
                     /locus_tag="ACG8LA_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349929.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0009432 - SOS response [Evidence IEA];
                     GO_process: GO:0018142 - obsolete protein-DNA covalent
                     cross-linking [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase"
     gene            complement(1988..2569)
                     /locus_tag="ACG8LA_001584"
     CDS             complement(1988..2569)
                     /locus_tag="ACG8LA_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFQ0203887.1"
                     /translation="MKTKEKILEATKDLIYKKGYHETSIRDILAASDTGKGQFYYYFS
                     SKKEVCLAVIHAHMDVWQTELFEDILNAGKQPEEALEEMLDWIFADHETQITYHGCPV
                     GNLIIELSTVDEEYRLLLLELVNQWVKYTKQNILALSEEKLSDEEADRQAKALIAEIQ
                     GSILLLKVTQDLSLLRQNFQLIKERLLTSQKVL"
     gene            complement(2752..3378)
                     /locus_tag="ACG8LA_001585"
     CDS             complement(2752..3378)
                     /locus_tag="ACG8LA_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HFQ0203888.1"
                     /translation="MFNNKNTAVVLTDPQVEFLKPAGGGFGLTKDILEKYNTIENMIE
                     MVKQAKEKGYKLFISPHYFYPHDHKWQFGGAGEHMMLEQQMFARKSQYESVEEGSGAD
                     FIEELKPYLDENTIISSPHKIFGPESNDLALQLRKNGIDTVILGGMNGNLCSDSHMRE
                     LVESGFNVVVATDAIGAPGQEAMDAALTNFGFIADQVMTTEEVLEQLS"
     gene            complement(3400..4731)
                     /locus_tag="ACG8LA_001586"
     CDS             complement(3400..4731)
                     /locus_tag="ACG8LA_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016668 - oxidoreductase activity, acting
                     on a sulfur group of donors, NAD(P) as acceptor [Evidence
                     IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HFQ0203889.1"
                     /translation="MMEKYQNIVIGFGKGGKTLAKALASKGESVLVVEKSTRMYGGTC
                     INIGCIPSKSLIFNGERGIDFTEAVARKEKLTGMLRAKNYHMISDEATGTVMDGTARF
                     LSNHQIEVTNNGEKVIVEGERIFINTGSEPIILPIKGLNTSRYLIDSTQAMDQEQLPE
                     KLVIIGAGYIGLEFASMFNEYGSKVVVLDAHSEFLPREDEDIAQMILEDMTNAGIEFH
                     LGVSVDQVADQESTAAVTFTEDGQEVTIQASKVLAATGRKPSTASLGLENTDVKLTDR
                     GAIAVDEYLRTDADNIWAIGDVKGGLQFTYISLDDYRIIMDQLKGENKRTTNNRKAVP
                     YSVFITPTLSNVGLTEKQAKAQGVNYKLFKYMTSGVPKAQVLEDPKGVFKVLVDPETD
                     LILGASIYAEDSHEVINLISLAMNGKLPYTLLRDQIYSHPTMSEALNDVLK"
     gene            complement(4886..5287)
                     /locus_tag="ACG8LA_001587"
     CDS             complement(4886..5287)
                     /locus_tag="ACG8LA_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HFQ0203890.1"
                     /translation="MKKAYETAMINHGGRNGEVEAPNGSMHMKITPPGIHAEGTNPEQ
                     LFAAGYASCFNGAVQHMIKEAGMTAESTVKARVSLYNLDDGGYQIGVVLEVHIDGISE
                     EEAQKIAEDAHEFCPYSKATRGNIDVEVTIV"
     gene            complement(5373..5579)
                     /locus_tag="ACG8LA_001588"
     CDS             complement(5373..5579)
                     /locus_tag="ACG8LA_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0203891.1"
                     /translation="MVTNMVIFLTVLVYGVNFLVYMYLKINHIKDYVEKIAIYFGTNM
                     TLLFTSSIFLFFGKIVEDGILVFE"
     gene            complement(5674..7176)
                     /locus_tag="ACG8LA_001589"
     CDS             complement(5674..7176)
                     /locus_tag="ACG8LA_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase/phosphoglucomutase"
                     /protein_id="HFQ0203892.1"
                     /translation="MKDMKALQNGSDIRGIALPVEGYEVNLTTDMVKKIGWGLANWIK
                     KKKKSTDPNKKWTIGIGHDSRISGPALKEALIQSLKEQGIHVIDFELATTPAMFMSTQ
                     FEQFSCDAAVMLTASHLPYYYNGIKFFTSEGGAEKEDIAFILSQQQKIKSEQTGSVEK
                     ADLLTPYAQDLVTKIKKGIGTLESKPLNGWKIIVDAGNGAGGFFAEKVLNSLGADSTG
                     SQFLEPDGRFPNHIPNPDNKEAMESIKQAVLANEADLGIIFDTDVDRSAVVSASGTVI
                     NRNNLIAVLSTIVLKEHPGTRIVTNSPTSSHLQRFIEEKGGIQVRYISGYRNVINKAL
                     ELNRLGKDTQLAIETSGHAAFKENYFLDDGAYVIAKILMLLPELKRKGITLDEQIKEL
                     KQPVEVQEIRLKLFSDEPREQGNKILEEMKRLLEEEKGMNFDPENEEGIRYDLEEPYG
                     NGWFLIRLSLHEPLLVLQIENDEFGKNKLALVKLAKLFGHFSDLESLTAE"
     gene            complement(7194..7649)
                     /gene="argR"
                     /locus_tag="ACG8LA_001590"
     CDS             complement(7194..7649)
                     /gene="argR"
                     /locus_tag="ACG8LA_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0006525 - arginine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HFQ0203893.1"
                     /translation="MKKKQRQALIRQIITEQPIGTQEELLARLHEAGADVTQATISRD
                     IREMKLVKSQNENKIVRYTLFNQPSVSLNEERLRTAIRREVLRIQSVQFMVIVLTERN
                     GADVVTNWLDEVAYPEVVGTMAGVDTFIIICRSEEEAQRFAEKLEKMRE"
     gene            complement(7747..8364)
                     /locus_tag="ACG8LA_001591"
     CDS             complement(7747..8364)
                     /locus_tag="ACG8LA_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HFQ0203894.1"
                     /translation="MEKIEWRKDKSYSMKKSPQILEVPKKSFFSIRGIGDPNQEDFKR
                     RVACLYAVSYAIRMSPKKNWLIPDYQMYTVYPLEGQWGLQEKYLHEPVMKKEHFSYQL
                     MIRQPDFVTEAIAQEAIQRSSKLPEDLKEQVVFKKMEEGLCAQILHVGPYAEEPATFE
                     KLEAFIAKEGYERASKEHKEIYISDPRKSAPEKMKTILRVKIEKG"
     gene            8585..9958
                     /locus_tag="ACG8LA_001592"
     CDS             8585..9958
                     /locus_tag="ACG8LA_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFQ0203895.1"
                     /translation="MTKQKQLLLVPAVIATGMMSFAGVLIETAMNVTFPTLIRQFDLT
                     TAQVQWVTTIYLLMISIIVPLSTYLNRNFSLKKLFLASNLLFLAGIMIDFFSPTFMVL
                     LFGRLLQGAATGIALPLMFHIILTFAPLNRRGAMMGVGTLTTAIAPAIGPTYGGIMTS
                     HFTWNHIFLFLVPVLFLSLIIGWFAIPEMAVQKSGYLDWISVLGICLLFSGSLTFLST
                     LGTVSSWIALIIGGIGWFLFYYRSKKVEHPLIRLSILSNKTFRLFLIGFLVYQFLLLG
                     VSFVLPNFLQIVQGSSPFVAGLAMLPGAAVGALLSPFSGKMLDQYGPKKPIFAGLILS
                     LIGWLALFLLIGHASVGVLIACHVFYMIGIGLSYSNMMTTGMNALNEELQGDGNAMFN
                     TLQQFSGAVATSLVAVIINYVQHHTSHNYEVSTTLGSKAALGVLLLLLLVSFARFAYY
                     LFFAKKA"
     gene            10033..11145
                     /locus_tag="ACG8LA_001593"
     CDS             10033..11145
                     /locus_tag="ACG8LA_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HFQ0203896.1"
                     /translation="MEKIAIIGGGIIGMTLASYLDTSKFNVALFDEGTGQATKASAGI
                     ISPWLSKRRNKQWYRLAKDGAAFFPKLIKDFQLDQTIYAQSGTLLLRPEKDLAELAVL
                     AEKRKEEAPEIGNIEWLSPEQTSQALPLLKPAVSLRISGGGRLDGKAYLEHLGQRLAQ
                     KQMEQIQAKVTLHKKSDSWLIKGPFGEYTADRVILTPGPALKPLLQELGYAADIRPQK
                     GQLLAFQTSYKMSQDWPVAMLDGEADFIPFMDGKILLGATHENDQGWDLAPTSEAYKG
                     LTKSTEQFLTDPDQIKNWPYEFRVGTRAYTSDFSPFFGVLPDDPSLLAASGLGSSGLT
                     TGPYIGYLLANFLNTGHWPTEDYQKDISTYITKNPS"
     gene            complement(11217..12854)
                     /locus_tag="ACG8LA_001594"
     CDS             complement(11217..12854)
                     /locus_tag="ACG8LA_001594"
                     /EC_number="4.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004612 - phosphoenolpyruvate
                     carboxykinase (ATP) activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxykinase (ATP)"
                     /protein_id="HFQ0203897.1"
                     /translation="MSTKESLELNEITSGNPLLSSIRSIVETTFYGNNVHEVFDRKTA
                     YQLAKGSPGTIITDLTISHAEELDLPADVRTLVFNDGSIVGRTASARRIFEDLDKEQS
                     KYEKILREAVYQSRKRQFYHTKVIVGLSEEFSVQSHLLIPEGFENNLYSYLLNFQPAN
                     SKILETYQKSVSFDEGDLYIFCDPEWTHETFPNGLILFDALHNTAAVLGLRYFGELKK
                     ATLTLAWALGNRNGFIACHGGMKQYASNDQTYTMAVFGLSGSGKSTITLAKHTEGHSV
                     SILHDDAFVISRKNGFATALEPSYFDKTQDYPSDDPAISSFLTCQNVGVTCTSKGEKV
                     LVTGDIRNGNGRTVKSRYATPDRVDHLSEKIDAVFWIMKDDSLPPIIKINDPVLAASF
                     GATLATKRSDAENITTKRQLDELVIEPFANPFRVYPLREDYQAFRELFLKQQTACYVL
                     NTGYFDDKKIKPETTLSIVERIVQQTAEFKSFGPFEDIHYLPIPDFPVSFEDTSYKNL
                     VKQRLDIRLRFIEAQIGKDLLPDEAKESLENLIQKLN"
     gene            complement(13022..13630)
                     /locus_tag="ACG8LA_001595"
     CDS             complement(13022..13630)
                     /locus_tag="ACG8LA_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HFQ0203898.1"
                     /translation="MNSFKKIVLGTTFAAGATAMFVGTTNAHADEVYTVKSGDSLSKI
                     SQKFAGDNSMIDAIAEKNSIANINRIYVGEQLTIPTSNDSSATTENKTTENTASTTET
                     ATQEHTYVAPVETVEVAPAAPAAATAPTSSSAKEWIAQKESGGSYTATNGRYIGRYQL
                     DASYLNGDYSAANQERVAEQYVTSRYGSWDAAKTFWLANGWY"
     gene            complement(14014..15165)
                     /gene="queG"
                     /locus_tag="ACG8LA_001596"
     CDS             complement(14014..15165)
                     /gene="queG"
                     /locus_tag="ACG8LA_001596"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0052693 - epoxyqueuosine reductase
                     activity [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA];
                     GO_process: GO:0008616 - queuosine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HFQ0203899.1"
                     /translation="MTLKEEIIQESKRLGIDKIGFTTAEPFDSLKESLEEQKAAGHTS
                     GFEHPNIDERLYPEMTFDQPKSIISIALAYPTRIHEEVPRDEKRGQFARASWGIDYHD
                     ILRDRLNRLIEFIQTRAEKWQKEEEWRLAPQVDTGELIDVAVAQRAGLGFIGRNGLLI
                     TEEFGSFVYLGEIVTNIVFEPDKPGEFGCGDCMRCVTACPTKALLGDGRMNAQRCLSY
                     QTQTKGMMPEEYRKKMRNVIYGCDICQLVCPYNQGKDFHFHEEMEPKVDEIYPKLKPM
                     LSMSNKDFKQQFGHLAGSWRGKKPLQRNALIALANLGDRTALPEISECLTDVRPVIRG
                     TAAWAIGRLGTKEPEKWLDVLDEILAKETEEVVINELEHAQKLLRRKLK"
     gene            complement(15184..15936)
                     /locus_tag="ACG8LA_001597"
     CDS             complement(15184..15936)
                     /locus_tag="ACG8LA_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0203900.1"
                     /translation="MNFTRKDKYTIKEEVFRLISQQENTDKDQDLQFLEAELAKLFIA
                     NQNETTEPDEELYIGKWLFDEFQPLDENTGIGYFVFLSPVGFTPGVLVKQNDEITVKA
                     WPALFSVIKAEGVIKKIQSAYYKSQFIANSKLMNMFYNRLVEIARPGKIPQTFTYTQQ
                     KNLYEEVLYSRDLSEFSPWEEVRLHELLSTKPVSLNFFNALDNKRKLISTNYWEVFAA
                     RKKWMEEKKIADQQIQFVQLKKEKLYYGLYSR"
     gene            complement(16077..17027)
                     /locus_tag="ACG8LA_001598"
     CDS             complement(16077..17027)
                     /locus_tag="ACG8LA_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HFQ0203901.1"
                     /translation="MKTKKSLFLILAVSFLVLAGCGKQASDQADEGSKEKLSVVATNS
                     ILADMAKEVGTDQIDIHSIVPVGTDPHEYEVLPEDIKKASDADVILYNGLNLETGNSW
                     FDNLMETAKKEEGKDYFAVSKNVEPLYLTSGEEHTKADPHAWLDLSNGIKYVEEIARI
                     FSEKDAENATLYKKNAEAYVEKLKELDTQAKESFASIEENKKLLVTSEGAFKYFSRAY
                     DLPAAYIWEINTESQGTPDQMKAIIDQIRAKEVPVLFVETSVDSRSMERVAKETGLKI
                     YDKLFTDSIAKEGEQGDSYYQMMKWNIETIHEGLSQTKES"
     gene            complement(17028..17867)
                     /locus_tag="ACG8LA_001599"
     CDS             complement(17028..17867)
                     /locus_tag="ACG8LA_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HFQ0203902.1"
                     /translation="MIQSFIDGLMNYQFLQYALVTSMLVGLASGVIGSFIILRGMSLM
                     GDAISHAVLPGVAISYMFGFSYIFGATAFGMLTAAVIGFVTQRSRLKNDTAIGIVFSS
                     FFALGIILISYAQSATDLYHILFGNVLAVRESDLLLTALVSGIVLIFVFFFYKELKIT
                     SFDPTMAKAYGLNTSLIHYLLMFFLTLVAVVSLQTVGTILVIAMLITPAATAYLLTNH
                     LLKMIITAAGIGMLSAVVGVFFSYSYNWPSGATIVLACTAFFILAFLFSPTKGILFQK
                     GSR"
     gene            complement(17864..18610)
                     /locus_tag="ACG8LA_001600"
     CDS             complement(17864..18610)
                     /locus_tag="ACG8LA_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HFQ0203903.1"
                     /translation="MERTAIVIQDLSAAYQGKTVLKTINLTINPQKITGIIGPNGAGK
                     STFMKSLLELIPATTGKVTFSGQSVNSVRKKIAYVEQRSELDLSFPIDVLGVVLLGTY
                     PSLRIGQRPGKKEKERARQALKKVGMEEYAKRQISELSGGQLQRVFIARALAQGAEWI
                     FLDEPFVGIDALSERKIFDILQELKNSGKTILIVHHDLHKVEEYFDEVILLNKQLIAS
                     GPVQEVFTSKNLQLAYGEIIRHLVKGGEKK"
     gene            18848..20218
                     /locus_tag="ACG8LA_001601"
     CDS             18848..20218
                     /locus_tag="ACG8LA_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015171 - amino acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFQ0203904.1"
                     /translation="MEEEKLTRSLSARHIQMIALGGTIGVGLFMGASSTIRWTGPSVM
                     GAYAIAGFFLYLIMRALGEMLYVDPSTGSFANYASEYIHPVAGYLTAWSNIFQYIVVG
                     ISEVIAVGSYMNYWWPDLPAIIPGIIVVLFLMLANLISVKAFGELEFWFSIIKVITII
                     LMIIAGLGVILFGFGNHGQAVGISNLWKNGGFFTGGVKGFFFALSIVVASYQGIELIG
                     MTAGEAENPKKTIIEAVQSTIGRILIFYIGAIFIIVSIYPWNQLSEIGSPFVQTFSKV
                     GITFAAGLINFVVITAALSGCNSGIFSASRMVYTLAINGKMSKKFLKLSRHGAPFYPV
                     VAISGGILIGLILNYLLPMFINQSENIFVFVYSSSILPGMVPWVVILISEIRFKKKHA
                     DKMHDHPFKMPLSPYTNYVTLAFLAIVLIFMFINPETRISLIIGLVFLLYMTIHYFVR
                     EKRTGK"
     gene            complement(20273..21169)
                     /locus_tag="ACG8LA_001602"
     CDS             complement(20273..21169)
                     /locus_tag="ACG8LA_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HFQ0203905.1"
                     /translation="MYDENEWGENVRMTRRRQQKQAARKRMIMIGAAVAVFLIIAGGV
                     AGLYFHGKNSSEAKSTTITETTTKKTETKQTSESSTKTKETQTSEEKTANGLPEQLQA
                     IVNDYSKKIEEKTPALIEEYQTEIQGNQEGIAGLSAVANQKARELQAISDEGIRKLRA
                     AYQAAENKDGVDLDTLINQLSANYTNHVAKISDIYLQTSASLQAESTSTQDTTSSDSE
                     TAESVEASEMQARTTQDTTDSSETNTNSATSQAATTVVLEGEGPNQIAERTGVPVETI
                     LSLNGMSMENYFLTPGETLKLN"
     gene            complement(21283..21453)
                     /locus_tag="ACG8LA_001603"
     CDS             complement(21283..21453)
                     /locus_tag="ACG8LA_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0203906.1"
                     /translation="MTNDWLIQQLDELSEKSEYQDRALLYEIKKLMAEIDERTMQLQG
                     EIDGQSWNHLNW"
     gene            complement(21450..22127)
                     /locus_tag="ACG8LA_001604"
     CDS             complement(21450..22127)
                     /locus_tag="ACG8LA_001604"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008753 - NADPH dehydrogenase (quinone)
                     activity [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0050136 - NADH:ubiquinone reductase
                     (non-electrogenic) activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HFQ0203907.1"
                     /translation="MRTLIIISHPTIEESLNQQFFKEASAGLPATWHHLESSYPDGKI
                     DIETELQLLAQHDRIIFQFPFYWYSSPAHLKIWQDNVLERAAHVLKGKELGIVLTTGV
                     AEKEYQAGGKEEYTISEFLRPYQRIANKFHMTYLPPFVLAQFMYLSQEKRWEKLIAYQ
                     QYLSLEGKPSLTQRIDWFIQRVQENQKMQEEESEKQAYIVEALTEAKEQIEDLTFTLQ
                     EMKGTSL"
     gene            complement(22218..23123)
                     /locus_tag="ACG8LA_001605"
     CDS             complement(22218..23123)
                     /locus_tag="ACG8LA_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family ligand binding domain-containing
                     protein"
                     /protein_id="HFQ0203908.1"
                     /translation="MEQSIFLKKEHQQVEKELYFDFCGFSKTMPFHSFGPAIRNDYIL
                     HVVMEGKGSYHVKNQQFQLKKGDLFLIRPGDSTFYLSDGEDPWMYCWLSFGGSAAEEI
                     IRQSLFREDQYTMVSSDIQKYIDIILECMKDTEETLENELQLTALTYRFLSVLLKDGG
                     KVSGGVQKVHSSLAVETVKYIEAHYAEKLSVEEIAQHLAVNRSHLSRVFKNHMGTSIK
                     EYLIGVRINRGAFLLSLTDESVESIAYQVGFNSLVVFSRMFKKSTGETATNYRKRMKN
                     ENFKNIALDTLKKQLEKQTAVSWTT"
     gene            23298..24722
                     /locus_tag="ACG8LA_001606"
     CDS             23298..24722
                     /locus_tag="ACG8LA_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015486 -
                     glycoside-pentoside-hexuronide:cation symporter activity
                     [Evidence IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside-pentoside-hexuronide (GPH):cation
                     symporter"
                     /protein_id="HFQ0203909.1"
                     /translation="MKSKMIQRVSYALGAFGHDTFYVTLSTYFMVFVTSQMFAGTDKA
                     TNAKMIATVTSLVVGIRLVEIIFDPLIGGIIDNTRTKYGKFKPWLVIGGVVSSVLLVA
                     IFTNFFGLATHNTTLFIILFAIVFILLDSFYSFKDIAFWSMIPALSTETKEREKFATF
                     ARFGSSLGANGTTLVVVPIVTFFTYLVTHKHIEGASGWFWFGVIAAVISGGTAIITAL
                     GTKEVDTAIRQQNEKAGIKDVFKAVAQNDQLMWLALAYIAYAIANAATTAVLFYFFKY
                     VLGQPTEFWIVGLVAALLGLVAVPLFPMLTRVISRRYVYLGGIAMMISSYFFFTIAGS
                     SLPIVIIGLVLFYFPQQLIFLSALMTITDSVEYGQWKNGIRNEAVTLSIRPLLDKIAG
                     ALSNGIVGFVAIASGMTGNATAADITAHGVTTFKAYAFYAPAALMIFSAIIFAWKITL
                     TEKKHAQIVEKLENKLAPADTMED"
     gene            24768..25799
                     /locus_tag="ACG8LA_001607"
     CDS             24768..25799
                     /locus_tag="ACG8LA_001607"
                     /EC_number="5.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase family protein"
                     /protein_id="HFQ0203910.1"
                     /translation="MKITEKDFGQGYHLITLENKNKLALSISDLGARIVSLKSNDREL
                     VLGFDTAEEYIEKDPYIGASIGRTAGRIENGRFSLNGKTYQLATDPKTGHNLHGGAPG
                     FELKKWSYVILNGENEASVIFTTTSPDGEHGFPGTMDVEIRYTLTKDNIWRVTSRGTS
                     DQDTLFNPTNHVYFNLTGDASQSIDQHELWLNSEAYAPLRTDSIPIGVKENAAGSAFD
                     FQIPKKLASVFASDLDQKNLVDGIDHPFFLKETGLGKEAARLTSPDKRIQVDIATDAS
                     SVVIFTANFGTETPEMRNRKLAHHGGITFETQTAPGAERFSAFGSIHLKAGSVFETVT
                     EFKIKTRKE"
     gene            25806..26993
                     /locus_tag="ACG8LA_001608"
     CDS             25806..26993
                     /locus_tag="ACG8LA_001608"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004335 - galactokinase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA];
                     GO_process: GO:0046835 - carbohydrate phosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HFQ0203911.1"
                     /translation="MEIKRSLNTKFAETFGPKKTTQYFSPGRINLIGEHTDYNGGHVF
                     PASITYGTQGVAAPRDDNKILVYSTNFDDIGVISFTLDELEYDKKANWANYVKGMVLK
                     LKEAGHSIDHGFELLVEGTIPNGAGLSSSASLELLVGVVLEDLFDLKTDRLELVQTGK
                     KVENEFIGVNSGIMDQFAIGFGELDHAILLDTNTLKYEMVPVKLDGYAIVIMNTNKRR
                     ELADSKYNERRSECEEALARLQKTLPISSLGDLDEEEFESTIDQIGDDTLIRRARHAV
                     SENQRTLKAKAELEAGNLEAFGQLLNDSHHSLRYDYEVTGIELDTLVDAAQKQEGVLG
                     ARMTGAGFGGCAIALVKEENIPAFKNNVYDEYMKVVGYAPEFYVAHIGNGTTKIDPEA
                     VHV"
     gene            27149..28531
                     /locus_tag="ACG8LA_001609"
     CDS             27149..28531
                     /locus_tag="ACG8LA_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HFQ0203912.1"
                     /translation="MWANQNPVFVYEKEPSRDILCIDCKSFYASVECVEKDLDPLTTK
                     LVVMSYPSDSTETRGSGLILASSPAAKKAYGITNISRARDLPFPYPSDLYIVAPRMAY
                     YMEKNREINSIYKKYADEANHHVYSVDESFLDVTNSMALFGKTNAYDMAKLIHKDVFE
                     QTGIYTTIGIGDNPLLAKLALDNGSKDGKQMFAEWRYEDVPEKLWKISDITDFWGIGK
                     RTAKRLKQMGIHSVYDLAHADYYHLKSKLGVIGTQLYAHAWGIDRSFLGQEYTPKSKS
                     IGNSQILDRDYTRREEIEIVIKEMADQVGTRLRRSAAKTQVVSLWVGYSLGYLDPNGK
                     TGFHQQMKIEATNASRDLADALLTIFHQHYHYQDIRRVGVNCSDLVYATGLQLNLFED
                     PEKQINEAKVDFVVDTIRKKYGFQSIIHAHSLLQGGRAIARSSLVGGHAGGMSGLEGG
                     KDETDSKKIH"
     gene            28568..28888
                     /locus_tag="ACG8LA_001610"
     CDS             28568..28888
                     /locus_tag="ACG8LA_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0203913.1"
                     /translation="MGDCFCDGRTSQRYQKNEEEARKQPLPKQQMTLQEIDSILTEAF
                     LSRKAVIIQLNLKDEFGRLLDEVEGHFIGEAYEDYFMIDHQPILWEDVRYIELKETKK
                     WFVT"
     gene            complement(29088..29756)
                     /locus_tag="ACG8LA_001611"
     CDS             complement(29088..29756)
                     /locus_tag="ACG8LA_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HFQ0203914.1"
                     /translation="MIFSITMKLVFGLIGLLLVVRLLGKKSMSEITPFDLVYTLVLGG
                     ILEESTYDDNVHVGHVLFAIALWAVMIYGIERIVQKNEKVNRWVKGEPSVLIKDGVIN
                     MTELTNNHIEMEQLRAILRQQECFFLENAKHVILENAGQMSVLKKSDEDKALSILLVD
                     EGQIQHKVLQSNQLTEAWLMENLKKEGYADVKQLIYVEWSEEKGLYILNKEDVMHESY
                     RIDG"
BASE COUNT         8404 a         6141 c         5473 g         9963 t
ORIGIN      
        1 attttttctt taactaaaaa aataatccaa gaaacattga acctatggat ccaaaagcta
       61 cccaaatact atagctaacc ccccgctacc ttcaattttg cagataaaac gctttgggag
      121 aaaatttcaa agacaacagg ccatcctatc atgcccgatt ataaacaaaa agctggctat
      181 tccttttgct ctgacaaatt tcaattggga aagttcacga aactagcagg tgaagaagtt
      241 tcaactgttc ggatcaaaga atgcccgctt caaatagaaa cattggttca acgaatttca
      301 actagacaag actttgctat tgtagaacgt gagatcgtag ctatttttgt agaagaaggg
      361 attttacatg atccaactca tatcaatgtg gataaatggc aacctcttat ctataaattc
      421 agagaatata caactgccaa ccagtcgtta actttgaatt ttagattcca agaattcaaa
      481 gagtcataat gataaacatc gttaggtata aataaaaaag actcgcagca cgagtaaaaa
      541 acaaatagaa gctatacatt agaaaggtcg actgtgaccc tatagatgca gtatatgcag
      601 cttatgagca tttcttctgt tctctttgtt tttgggatct gtgctgaagt ctttttcgtt
      661 ttttgccgct ctttctttga aaaatcgatt atgttatacc ttctccatta ctaattcagg
      721 catctgctga gtaatgattt ttcgcgcaaa agaaatatct gttacccaag gttcgatttg
      781 ttcttcagtc aagacaagcg gcattcggtc atggattggt gcgactgtgc ggttaggttc
      841 agtagtcatt atgattgatt ctgccatttt ttcatcctga tggctacgat aaaaaccgcc
      901 aatatacact attttttcct tatttgaaaa cataaatttg tctttttctt cattccactc
      961 attgggaaaa cacaacgatt ttgcaaaaat ggttgatgaa aggtcttttt ttcttctact
     1021 gtctctgcac gggcattaat catcaattgt ccttttttaa atccggtaaa tccccacttc
     1081 atgatttccg gagtgaggat gttttcttcc tcttttctta acgtcacaac aagatttgac
     1141 ggaaaaactt ctccagctgc taattctgct gcctgcttcg gttgtttcgt ctgggcttct
     1201 cgataataat tctgaaggag ctctgactct agatcaaaaa aataacgacc acacatccta
     1261 atccctccca atcttttttt ctatcataca ctgcaacaag aagttcgcac caacaaaacg
     1321 ctttcaattt ttgtagaact aaaaaagttg tgacaagtga caaactctcc agtgaatggt
     1381 attctcctgc caactcctcg gtcacaagtc acaatattca acaaacatga gaagctgctt
     1441 tttgaaattg ttccttgtga ctcggagtga aacggcaggc ttacgacctc tgggtaaacg
     1501 gtgttcaaaa gccagtttct cggtattaag ccaaatttat gcaaaaatgt agaaagctat
     1561 tttcacaaaa tttttcttaa tactcgaaac taagcgactt tttcacaacc tcttccttaa
     1621 acggtgttca aaagcttgca tctgcggtaa taagcccaac caaacgaaaa atatgagcag
     1681 ctatttttat ttggctgttc ttattacttg atgcagggca gctttttcac aacctctcca
     1741 ctaaacggtg ttcaatcagc taaccttcgg tattagctca aaaaacggca aaatatgagg
     1801 aactattttg ccgtttgttt ctctaatact caggtcaaag cgctgatttc acaacctcta
     1861 atacacggtg ttccagaagt agcttcttcg aaaaataagc cgaaatttca caaaaatttg
     1921 agaagcaatt ttcgtaaatt ccttcttatt tcttgaagct gaccacttct gtcacaacct
     1981 ctaattatta aagaaccttt tgcgaagtta acaatctttc tttgatcaat tgaaaattct
     2041 gcctaagtag tgatagatcc tgtgtgactt tcaacaataa gatacttccc tggatttcag
     2101 caatcaacgc tttggcttga cggtctgctt cttcatcgga cagtttttct tcagaaagtg
     2161 ccaggatatt ttgtttcgta tacttgaccc attgattgac taattctagt agcaacagac
     2221 ggtattcttc atccactgta ctcaactcaa taatcaaatt acctacagga cagccatgat
     2281 aagtgatctg tgtctcatga tcagcgaaaa tccagtccaa catttcttct aatgcttctt
     2341 ctggctgttt tccagcattt aagatgtctt cgaacaattc tgtctgccat acgtccatat
     2401 gcgcatggat caccgctaga caaacttctt tttttgaaga aaagtaataa taaaattgac
     2461 cttttcctgt atcagaagct gctagaatat ctcggattga cgtttcatga tagccttttt
     2521 tataaataag atctttggtc gcttccaaga tcttttcctt tgttttcaat gatattctcc
     2581 tttttcattt ctcatagtcc tatattatac agtaaattca tcattttttc ttcttaatcg
     2641 tttaaaaaag actgtgccaa attatctgac acagccctca ctataaaact gttctcatat
     2701 agctagatgt tcattgattc aagaactgcg aggacaaaag caattcctat cttatgatag
     2761 ttgctctaat acttcctctg ttgtcatcac ttgatctgca ataaagccaa agttcgtcaa
     2821 cgctgcatcc attgcttctt ggccaggagc accaattgca tctgtcgcta ccacaacatt
     2881 gaatccactc tctaccaatt cacgcatatg ggaatcgcta cacaagtttc cgttcattcc
     2941 accaagaatt actgtgtcga ttccattttt tctcaattgg agcgccaaat cattgctttc
     3001 tggtccaaag attttatgag gagagctgat gatcgtattt tcatccaaat aaggtttcaa
     3061 ttcttcgata aaatcggctc ctgaaccttc ttccactgat tcatattgac tttttctagc
     3121 aaacatctgc tgctcaagca tcatatgttc tcctgcaccg ccaaattgcc atttatggtc
     3181 atgtgggtaa aaataatgag gagaaataaa gagtttgtat cctttttctt ttgcttgttt
     3241 taccatttca atcatatttt cgatcgtatt gtatttttct aagatatctt ttgtcaaacc
     3301 aaagccaccg cctgctggtt tcaagaactc gacttgcggg tcagtgagaa ctactgctgt
     3361 atttttatta ttgaacatgg tggattctcc attcgttatt tattttaata catcatttag
     3421 agcttcactc attgtcggat gagaatagat ttgatctctc aataacgtat aaggaagttt
     3481 tccattcata gctagcgaaa tcaagttgat gacttcatga gaatcttccg catagatact
     3541 tgcccctaga atcaagtcag tttcagggtc gactaaaact ttgaatacac ctttaggatc
     3601 ttctaatact tgtgctttag ggacaccgct tgtcatatac ttgaataatt tgtaattgac
     3661 gccttgtgct ttggcttgtt tttctgttaa acctacattg gataaagtcg gagtgataaa
     3721 tacactgtaa ggcacagctt tccggttatt cgttgttcgt ttattctcgc ccttcaactg
     3781 atccataatg attcgataat catctagaga gatataagtg aactgcaatc cgcctttgac
     3841 gtctccaatc gcccaaatgt tgtctgcatc tgtacgaagg tattcatcca cagcgattgc
     3901 tccgcgatct gttagtttaa catctgtatt ttctaatcca agtgatgctg tacttggttt
     3961 tcttccagtt gcagccaaaa cttttgacgc ttggattgtt acttcttggc catcttctgt
     4021 aaaggtgacg gcagctgttg attcttggtc tgctacttga tctacagata cacctagatg
     4081 gaattcgatt cccgcatttg tcatgtcttc taaaatcatt tgcgcgatat cttcatcttc
     4141 acgtggaaga aattcagaat gggcatcaag aacgacaact ttagatccgt attcattgaa
     4201 cattgatgca aattccaagc caatatatcc agccccgatg atcactaatt tttccggtaa
     4261 ttgttcctga tccatcgctt gcgtagaatc aatcaagtag cgacttgtat tcaatccttt
     4321 gattggtaaa atgattggtt cagaaccagt attgatgaaa atccgttcgc cttcaacaat
     4381 cactttttca ccattattcg tcacttcgat ttgatggtta gaaagaaaac gtgctgtacc
     4441 gtccatcact gtcccagttg cctcatcgct gatcatatga taatttttgg cgcgaagcat
     4501 gcccgtcaat ttttctttcc gagcaacagc ctctgtaaag tcgattcctc tttctccatt
     4561 gaaaatcaat gatttagaag gaatacagcc gatgttgata catgttccgc catacatacg
     4621 tgttgacttt tcaacgacta aaaccgattc accttttgaa gctaacgcct tcgctaaagt
     4681 cttaccgccc tttccaaaac cgatcacaat attttgatat ttttccatca tttttccctc
     4741 gcttcttttt tacctaccga ttggtacaaa aatatgataa ccgataattg tctattctcc
     4801 aaatcatctg ctttatttgt caaaaaaaac cagacaaaaa gcggtccttt cacgttttta
     4861 gtctggttcg atttccttta ttcttctaaa caatcgttac ttctacatcg atatttcctc
     4921 tagttgcttt ggagtaaggg cagaattcat gcgcatcttc tgcaattttt tgggcttctt
     4981 cttcgctgat gccatcgata tgcacttcta atactacacc gatctgatag ccgccatcat
     5041 ctaaattata aagagagaca cgtgctttta ctgtggactc tgctgtcatt cctgcttctt
     5101 tgatcatatg ttgtaccgcc ccattgaaac aagaagcata acctgctgca aataattgtt
     5161 ctggatttgt tccttctgca tggattcctg gaggagtgat tttcatatgc atcgagccat
     5221 ttggtgcctc gacttctcca ttgcgcccgc catggttgat cattgctgtt tcgtatgctt
     5281 ttttcattgt actgctcctt tcgattgacc atttgctact tggctataat tatagtgtat
     5341 gacaagtaag gcgctttcta caaaaattct gcttattcga ataccagaat gccgtcttct
     5401 actatttttc caaaaaacaa aaaaatacta ctcgtgaaca acagcgtcat atttgttcca
     5461 aaataaatag caatcttttc tacataatct tttatatgat tgattttaag atacatatat
     5521 accagaaagt tgaccccata aaccaatact gttaaaaaaa taaccatatt cgttaccatt
     5581 ttttcctcct tttgctggtc tccctaccag cactcgattt aaccatacca ctttttttgc
     5641 cgtccaagca actagccttt caaaaagact ggtttattct gctgttaatg attcaagatc
     5701 agaaaaatgt ccgaataatt ttgctaattt tactaacgcc aacttgttct ttccgaattc
     5761 atcattttct atctgtaata ctagtaacgg ctcatgtaag cttaaacgga tcaaaaacca
     5821 gccgtttccg tatggctctt ctagatcata tcgaatacct tcttcatttt ccgggtcgaa
     5881 gttcatccct ttttcttctt ccaacagtcg cttcatttct tctaatatct tgtttccttg
     5941 ttcgcgtggt tcatcgctga acaattttaa tcggatttct tgtacttcta cgggctgttt
     6001 caactctttg atttgttcat ctaatgtgat accttttctt tttaattctg gcaaaagcat
     6061 caggatcttt gcgatgacat atgcaccatc atccagaaaa tagttttcct tgaatgcagc
     6121 gtgtccgctt gtttcgatgg ctagctgtgt atctttccca agacggttaa gttctaatgc
     6181 tttattgatt acatttcgat agccggaaat ataacgaact tggatgcctc ctttttcttc
     6241 aatgaatctt tgtagatgag aagaagtagg ggaattcgtc acgattcttg ttcctggatg
     6301 ctcttttaat acgattgtac ttaatactgc gatcaaatta tttcgattga tcactgttcc
     6361 agaagcactg acaactgcag aacgatccac atctgtatcg aaaatgatcc caagatctgc
     6421 ttcatttgct aaaacagcct gcttgatact ttccatcgct tctttattat caggatttgg
     6481 gatatgatta ggaaatcggc catctggttc caaaaattgg gaacctgttg aatccgcacc
     6541 taagctattc aatacttttt cagcaaagaa tccaccagca ccatttccgg catcaacaat
     6601 gattttccaa ccatttagtg gtttgctttc tagtgttcca atcccctttt taatttttgt
     6661 gactaaatct tgcgcataag gtgtcaaaag gtctgctttt tctacgcttc cagtttgttc
     6721 gctttttatt ttttgctgct gtgataggat aaaagcaata tcttcttttt ctgctcctcc
     6781 ttctgaggta aagaatttta ttccattata ataataggga agatggctag cagtcagcat
     6841 aaccgcagca tcgcacgaga actgttcaaa ttgagtggac ataaacatag caggcgtagt
     6901 agctaattcg aaatcgatga catgtatccc ttgttctttc agactttgga tcaacgcctc
     6961 tttcagtgct ggtccgctta tcctactgtc atgaccaatc ccaatcgtcc attttttatt
     7021 tggatcggtt gatttcttct ttttctttat ccagtttgct agtccccagc cgatcttttt
     7081 taccatgtct gtcgtcaagt ttacttcata tccttcaact ggtaatgcga ttcctcgaat
     7141 atccgatcca ttttgcagcg ctttcatatc tttcatataa aagtcctcct catttattcc
     7201 ctcatttttt ccagcttttc tgcaaatcgc tgtgcttctt cttctgagcg gcaaataata
     7261 atgaatgtat ctacaccggc catcgttccg acaacttcag ggtaagccac ttcatctagc
     7321 caattcgtta ccacatcggc accatttcgt tcagtcaata cgataaccat gaactgaaca
     7381 gactggatac gcaaaacctc gcgtctaatt gctgtacgca aacgttcttc atttaaagaa
     7441 acagatggct ggttaaataa tgtatagcgt actattttgt tttcattttg actttttact
     7501 aacttcattt ctcgaatgtc tcgagaaatc gttgcttgag tcacatcggc gcctgcttca
     7561 tgcagccgcg caagcagctc ttcctgtgtc ccaataggtt gttctgtaat gatctggcgg
     7621 atcagtgctt gtcgctgttt ctttttcata ttagacacct ctcaatgttg attatagcaa
     7681 aagataagta atatttcttc atattttggt attttttact tttatttttt gttttcattc
     7741 aggttgctaa cctttttcta ttttaacacg caaaatcgtc ttcatttttt caggtgctga
     7801 ttttcttgga tcgctgatgt aaatctcttt gtgttcttta gaagctcttt catagccttc
     7861 ttttgcgatg aatgcttcta atttctcaaa cgttgctggt tcttcggcat agggcccgac
     7921 gtgtaagatt tgggcacaaa gaccttcttc catctttttg aatactactt gttctttcaa
     7981 gtcttccgga agtttgctag aacgctgaat ggcttcttgt gctatcgctt ctgtaacaaa
     8041 gtcaggctgt cggatcatca attgataaga aaaatgttct tttttcatca ctggttcatg
     8101 caaatacttt tcttgcagtc cccattgtcc ttccagtgga tagacagtat acatctgata
     8161 atcaggaatc agccaatttt ttttaggcga catgcgtatt gcatagctga ctgcatatag
     8221 acaggctact cttcgtttaa agtcttcctg attcgggtcg ccgatccctc tgatgctaaa
     8281 gaatgatttt ttaggaacct ctagtatttg cgggcttttt ttcatactat agctcttgtc
     8341 tttacgccat tcaatttttt ccatttttct tcctccgcga aattccattt agttatttat
     8401 tatcatacct ctttttgagt gacttggcta atcgtgttga cactattttt cagtttgtgc
     8461 tagaataagt gaagtaaata aatcgtacag ataacacgtt tcggcgtgtc gagagagagg
     8521 cggtttctat ttttataata gaaatcactc tcttttttta cgaaattttt tagaggtgat
     8581 gtaaatgaca aaacaaaaac agctgctttt agtacctgca gtaattgcaa cagggatgat
     8641 gtcttttgcg ggcgtattga tcgagacggc catgaatgta actttcccaa ctcttatcag
     8701 acagtttgat ttaacgactg cacaagtcca atgggtaaca acgatttatc ttttgatgat
     8761 ttcgatcatt gttccgctgt ctacttattt gaatcgcaat tttagtctca aaaaactctt
     8821 tttagcttca aatctgcttt tcttggcagg tataatgatc gatttcttct ctcctacctt
     8881 catggtccta ttgtttggtc gattgctcca aggtgcagcg acaggtatcg ctcttccgtt
     8941 gatgttccat attatcttga catttgcccc cctcaatcga cgaggcgcga tgatgggtgt
     9001 cggtactttg acaacggcca ttgctccagc aattggcccc acttatggag gcattatgac
     9061 ttcacatttt acatggaatc atatcttcct gtttcttgtg cccgttttgt ttctttcttt
     9121 gattatcggc tggtttgcta ttcccgagat ggcagtacaa aaaagtggtt atttggattg
     9181 gataagcgtt ttaggaattt gtcttttgtt tagtggaagt ctaacatttt tgagtacgtt
     9241 gggaacagtt tccagctgga ttgctttaat catcggcggt attggctggt tcctttttta
     9301 ctatcgaagt aaaaaagtgg agcatccact gatccgactg tctattcttt caaataaaac
     9361 attccgcttg tttttgattg gcttcttagt ttatcagttt ttattacttg gtgtatcttt
     9421 tgtcttgccg aatttccttc agatcgttca aggaagtagt ccttttgtcg ctggattagc
     9481 gatgcttccc ggcgcagcgg ttggtgcttt gctttctcct ttttccggga aaatgctgga
     9541 tcaatatggt ccgaagaagc caatttttgc tgggctgatt ctttctttga ttggttggct
     9601 agcattattc ctactcatag gacacgcttc agtgggtgta ttgattgctt gtcatgtgtt
     9661 ttatatgatc ggtatcggat tatcttacag caatatgatg accaccggaa tgaatgcact
     9721 gaatgaagaa ctacaaggag acgggaacgc aatgttcaat accttgcagc agttttctgg
     9781 cgctgtggct acttcattag tagcggtcat tatcaattac gtccagcatc atacttccca
     9841 taactatgaa gtgtctacta cattaggatc aaaagcagca ttaggcgtct tgttgctgtt
     9901 gcttctcgta agctttgctc gattcgccta ttatctgttc tttgctaaaa aagcgtagat
     9961 tccatatacg gcaggtgttg catctgccgt ttttttgtgt gaaaatggtt gtttgtaaaa
    10021 ggaggctttt ttatggaaaa aattgccatt atcggtggcg ggatcattgg tatgacccta
    10081 gccagttact tagatacatc aaaattcaat gttgctttat ttgatgaagg gacaggacag
    10141 gcaactaaag ctagcgctgg gattatctcc ccttggttgt cgaaacgcag aaacaaacaa
    10201 tggtatcgtc tggctaaaga cggcgctgct tttttcccta aacttataaa agatttccaa
    10261 cttgatcaaa cgatttacgc acaatcaggg acacttttgc ttcgacctga aaaagattta
    10321 gctgaattgg ctgttcttgc cgagaaacga aaagaagaag cgccagaaat tggaaacatc
    10381 gaatggcttt cacctgaaca gacatctcaa gcacttccgt tattgaaacc agcagtttca
    10441 ctgcgtatca gtggtggtgg tcgtctggat ggaaaagcat atttagaaca tcttggtcag
    10501 cgtttagcac aaaaacaaat ggagcagatc caggcaaaag tcactttgca taagaagagc
    10561 gattcttggc tcatcaaggg accgtttgga gaatacacag ctgatcgtgt aattttgaca
    10621 cctggcccgg cacttaagcc tttattacaa gaattaggct atgctgcaga tatacgtccg
    10681 caaaaagggc agctcttagc atttcagaca tcttataaga tgagtcaaga ctggcctgtt
    10741 gctatgcttg acggagaagc tgatttcatt cctttcatgg atggaaagat ccttttaggt
    10801 gctacccatg aaaacgatca aggctgggat ttggctccta ctagcgaagc ttataaggga
    10861 ttgactaaga gtacagaaca gttcttgact gatccagatc agataaaaaa ctggccatac
    10921 gagttccgtg taggtacccg tgcttatacg tcagattttt ccccattttt cggcgtactg
    10981 ccagatgatc caagcttact ggctgctagc ggtctaggct cttctggctt gaccacaggt
    11041 ccttatatcg gctatctatt agccaacttc ttaaatactg gtcattggcc tacggaagat
    11101 tatcaaaagg acatctccac ctatattacg aaaaatccat catagaaaaa cagctttttc
    11161 aagtaaggat cccgagcgat attgcgcatg gattacttct tgaaaaagct gttattttag
    11221 ttcaatttct gaatcaaatt ctccaaactt tcttttgctt catctggcaa gagatctttt
    11281 cctatctgag cttcaatgaa tcgtaaacga atatcaagtc gttgtttcac cagattttta
    11341 taggacgtat cctcaaaaga aacaggaaaa tctggtatag gtaaatagtg gatgtcttca
    11401 aatggaccaa acgacttgaa ttctgccgtt tgttgcacga ttctttcaac gattgacaat
    11461 gtcgtttcag gtttgatttt tttatcatcg aaatatccag tattcaggac atagcaggct
    11521 gtttgctgtt tcaaaaacaa ctctcgaaaa gcttgatagt cttccctaag aggatagaca
    11581 cggaaaggat tagcaaatgg ttcaatgact agctcatcta gctgtctttt tgtagtgata
    11641 ttttccgcgt ctgatcgttt tgttgctaat gttgcaccaa aagacgctgc taaaactggg
    11701 tcattgatct tgataattgg cggaagcgaa tcatctttca tgatccaaaa aacagcatcg
    11761 atcttttcgc taagatgatc gactcggtcg ggtgtcgcat aacgtgattt gactgtccgc
    11821 ccatttccgt ttcgtatatc tcctgttact aggacttttt ctcctttact tgtacatgtc
    11881 acgcccacat tctgacaagt aaggaaagaa gaaatggccg gatcatcaga cggatagtct
    11941 tgtgttttat caaagtaaga aggttccaag gcagtagcaa aaccattttt tcgagaaata
    12001 acgaaagcat cgtcatgcaa gatcgaaaca gagtgacctt ccgtatgttt tgctaaggta
    12061 atcgttgatt ttccagaacc ggacaaccca aatacagcca tcgtataggt ctggtcatta
    12121 ctagcatatt gtttcatccc accgtggcag gcaataaagc cattgcgatt tcccaatgcc
    12181 caagcaagcg tcaaagtcgc tttttttaat tctccaaagt aacgtaatcc tagcacagcc
    12241 gctgtattat ggagagcatc aaacaaaatg agtccatttg gaaatgtttc atgtgtccat
    12301 tcgggatcac aaaagatata aagatctccc tcatcaaagg aaacagactt ttgataagtc
    12361 tctaagatct tcgaattcgc tggctgaaaa ttcagcaaat aagaatacaa attgttctca
    12421 aatccttctg gaatcagcaa atgactttgc acagaaaatt cttcagatag gccaacgatt
    12481 acttttgtat ggtaaaactg gcgcttgcga ctttgataca cagcttctct taaaattttc
    12541 tcgtatttgc tttgttcctt gtctaagtcc tcaaagatcc gccgagcact tgctgttctt
    12601 cccacaatgc ttccatcatt gaatactagt gtcctaacat cagctggtaa atctagttct
    12661 tcagcatgtg agattgttaa atctgtgatg atcgttcctg gactcccttt tgctagttga
    12721 taagctgtct tcctatcaaa aacttcatga acattattac cgtaaaatgt cgtttctaca
    12781 atcgatcgaa tactggataa cagtggattt ccacttgtga tttcgtttaa ttcgagactc
    12841 tcttttgtac tcatggctcc tcctcattcc ctaaacaaaa aaacgttttc tttattatac
    12901 attattcgag tttttatttg tactgctgcg ctgtgggaag caaacgagtt atttttcaca
    12961 caaaaaaacc gagaacttga ataaacaagt ttctcggttt catcattttc cttttatcgg
    13021 cttagtacca gccgtttgct aaccagaatg ttttagcagc atcccatgaa ccataacgag
    13081 atgttacata ttgttctgct acacgttctt gattggcagc tgaatagtcg ccgtttaagt
    13141 atgaagcatc taattgataa cggccgatgt aacgtccgtt agtagctgtg tatgaaccgc
    13201 ctgattcttt ttgtgcgatc cattcttttg cagagcttga agttggcgct gttgcagcag
    13261 ctggggcagc aggagctact tcaactgttt caacaggtgc aacgtatgta tgttcttgcg
    13321 ttgctgtttc agttgtagat gctgtatttt ctgttgtttt gttttctgtt gttgctgaag
    13381 aatcatttga agttgggatt gttaattgtt caccaacata aatgcggttg atgtttgcga
    13441 tcgaattttt ttcagcaatt gcatcgatca ttgagttgtc tcctgcaaat ttttgtgaga
    13501 tcttagataa tgaatcacct gattttactg tataaacttc atcagcgtga gcatttgtag
    13561 ttcctacaaa cattgcagta gcaccagcag caaaagttgt acctaaaaca attttcttaa
    13621 atgaattcat attaaactcc tttttttctc cgttttttat tctttcgacg ctattaactt
    13681 tatcatttag aaatatttca taggtaaaag aaacatgaca tttaatgaca aaataacgaa
    13741 ttatttaata tttgtaacat ttaaacaaat atttttttga tacaaaacca taaaagcctt
    13801 gttgtataag caaagtaatc gtttttctat gtttttttat ttttgaatga aaaacgcaga
    13861 ttctgtaaca ttcactgcaa taatccataa aaaaaagcaa aaaaattttt gatttttatc
    13921 aaattctctt aaaaaaatgt aaaaaataca aaaaaaccag taattgttac aacaattact
    13981 ggacaaaaac tttgaataat gttaactatt tttttatttt aactttctcc gcaataattt
    14041 ctgggcatgt tccaattcgt ttataacgac ttcttctgtt tctttagcta atatttcatc
    14101 taatacatca agccattttt ccggttcttt tgttcctaga cgtccaatag cccaagctgc
    14161 tgttcctctg atgacagggc ggacatctgt taaacattct gaaatctcag gcaatgccgt
    14221 tcgatcacct agattagcta aagcaatcaa tgcgtttctc tgcaaaggtt tcttcccacg
    14281 ccatgaacca gctaaatgcc caaattgctg tttgaagtct ttattagaca tcgaaagcat
    14341 tggctttaat tttggatata tttcgtctac ttttggttcc atctcttcat gaaaatgaaa
    14401 atcttttcct tgattgtaag ggcagactaa ctggcagata tcacatccat aaatgacatt
    14461 tcgcattttt ttacgatatt cttccggcat catccctttt gtctgagttt gataagacaa
    14521 acatcgctgg gcattcattc ttccgtcacc aagcaatgct tttgtcggac aagcagtcac
    14581 gcagcgcata cagtcaccgc aaccaaattc tcctggttta tcaggctcaa atacaatatt
    14641 agtaacgatc tcaccaagat agacaaatga accgaactct tcagtgatca acaatccgtt
    14701 tcgtccaata aatcctaaac cagctcgctg tgctacagcg acatcgatca gttctccagt
    14761 atctacttgc ggagctagac gccattcctc ttctttttgc catttttctg ctcttgtttg
    14821 gatgaattcg atcaatcggt tcaaacggtc tctgagtata tcatggtaat cgatccccca
    14881 agaagcacga gcaaactgcc cgcgtttttc atccctaggc acttcttcat ggatcctagt
    14941 aggatacgca agtgcaatgg aaatgatcga tttcggctga tcaaatgtca tttctggata
    15001 aagacgctca tcgatatttg gatgttcaaa gccagaagta tggccagctg ctttttgttc
    15061 ttccaacgat tcttttaatg aatcaaaagg ttccgccgtg gtgaacccga ttttgtcaat
    15121 tcctaatcgt ttgctttctt gtatgatttc ttcttttaat gtcatggtct tcctcgcttg
    15181 ctgttaacgg ctgtataacc cataatatag tttttctttt ttcagctgga caaactggat
    15241 ctgctgatcg gcaatcttct tttcttccat ccattttttt cttgcagcaa atacttccca
    15301 ataatttgtt gaaattaatt ttcttttgtt atctaatgca ttaaaaaaat tcaatgaaac
    15361 tggttttgta cttaacagtt catggagcct tacctcttcc catggcgaaa actcagacag
    15421 atcgcgggaa tacaatactt cttcatagag atttttttgc tgtgtgtacg tgaatgtttg
    15481 cgggattttc ccaggcctag caatttctac tagacgatta taaaacatat tcattaattt
    15541 gctgttggca ataaattgac ttttataata ggccgactgg atctttttga ttactccttc
    15601 tgctttgatg actgaaaata atgcaggcca tgctttgacg gttatttcgt cgttttgttt
    15661 aactaatacg ccaggtgtga agccgactgg agaaaggaac acaaaataac cgataccggt
    15721 attttcatct aaaggctgaa attcatcaaa caaccatttg cctatgtaca gctcttcatc
    15781 tggttctgtt gtctcatttt gatttgctat gaataattta gctaattctg cttcaagaaa
    15841 ttgaaggtct tgatccttgt cggtattttc ctgctggctg atcaatcgaa agacttcttc
    15901 tttaatcgta tatttatctt tacgtgtaaa attcatagcc acaccttcct tccttactct
    15961 aactataacg gaatttcttc aaaaaaggta tctgtacgac gaaaaacagc ataatttttt
    16021 ttcatatctc ttataaaaaa tgcaaggtct gctcctcaag ctagaccttg cacttttcag
    16081 ctttcttttg tttgtgacaa accttcatgg atcgtttcaa tattccattt catcatctga
    16141 tagtaagaat ctccttgttc tccttctttt gctatggaat cagtgaacag tttatcatag
    16201 attttcaaac ccgtttcttt tgctacccgt tccatgcttc ttgagtctac actggtttcc
    16261 acgaataaaa ccggtacttc ttttgctctt atctgatcaa tgatcgcttt catttgatca
    16321 ggcgtacctt gactttctgt attgatctcc catatataag ctgctggcaa atcatatgct
    16381 cgtgaaaaat acttgaatgc cccttcactt gttactaata attttttgtt ctcttcgata
    16441 gaagcaaaac tttccttcgc ttgtgtatct aattctttta gtttttccac atatgcttct
    16501 gcattttttt tatagagtgt cgcattttct gcatcttttt cagagaatat acgtgcgatt
    16561 tcctccacat attttattcc gttagatagg tctagccaag catggggatc tgcttttgta
    16621 tgttcttcac cgctagttaa ataaagaggt tctacatttt tgctaactgc aaaataatct
    16681 tttccttctt cttttttagc cgtttccatc aagttatcga accagctgtt acctgtttca
    16741 agattcaaac cgttgtataa aataacatct gcatcgcttg cctttttgat gtcttctggt
    16801 agtacttcat attcatgcgg atctgttccg actggtacga tactgtggat atctatttga
    16861 tctgttccga cctcttttgc catgtccgcc aagatcgaat tggtagccac gactgacaac
    16921 ttttctttac ttccttcatc cgcttggtca gaagcctgct ttccgcaacc ggctaatacc
    16981 aagaaactaa ctgccaagat taaaaagagt gatttttttg ttttcatcta tctgcttcct
    17041 ttctgaaata aaattccttt tgttggagaa aataaaaaag caaggataaa aaatgcggta
    17101 catgctaaca cgatcgtagc tcctgatggc caattgtaac tataactgaa aaacacaccg
    17161 acaactgcac ttagcatacc gattcctgca gctgtaatga tcattttcag taaatggttc
    17221 gttagcaagt aagccgtggc ggctggtgtg atcaacatgg caatcaccaa gattgttcct
    17281 actgtctgta aactgactac agccactaat gtcaaaaaga acatcaaaag ataatggatc
    17341 agcgatgtgt tcagcccata agcttttgcc attgtcggat cgaatgatgt gatcttcaat
    17401 tctttataaa agaaaaagac aaatatcaag acgattccac taacgagtgc tgtcagcaac
    17461 aaatcgcttt ccctaacagc taagacattc ccaaataaaa tatgatacaa atctgtcgca
    17521 ctctgggcat atgaaatcaa gataatccct aatgcaaaaa aggagctaaa gacaattcca
    17581 atcgctgtat catttttcaa tcggctccgc tgagtcacga aaccaatcac tgctgctgtt
    17641 agcatcccaa aagcagtggc tccaaagatg taactaaaac caaacatata agaaatggct
    17701 acacctggaa gaactgcgtg agagatagcg tctcccatca aagacatccc tcgtaaaata
    17761 ataaaagaac cgatgactcc agaagcaagt cctacaagca tggaagtgac caaagcgtat
    17821 tgcaggaatt gataattcat taatccatca ataaaggatt ggatcatttt ttctctcctc
    17881 cttttactaa atgtctgatg atctcaccat aggccaattg aaggttcttc gatgtaaaga
    17941 cttcttgtac tggaccggaa gcgatcagct gtttatttaa aagaataacc tcatcgaaat
    18001 attcttctac tttatgaaga tcatgatgga cgatcaaaat cgtttttcct gaattcttca
    18061 attcctgcaa gatgtcaaag atctttcgtt cacttaacgc atcaatccct acgaatggtt
    18121 catctaaaaa gatccattct gctccttggg ctagagctct tgcaataaaa actctctgaa
    18181 gctgtccacc cgatagttcg ctgatctgtc ttttggcata ttcttccatc cctacttttt
    18241 tcaaagcttg tcttgcacgt tctttttctt ttttcccagg tctttgtcca attcgtaaag
    18301 atggatatgt tcctaaaagt acaacgccta atacatcaat tggaaaggaa agatccaatt
    18361 cacttcgctg ttccacgtag gctatttttt tacggactga gtttaccgac tgtccagaaa
    18421 aggtgacttt accagtagta gctggtatca actctagcaa agatttcata aatgttgatt
    18481 ttcctgcacc gtttggtccg ataataccgg taattttttg tggatttatc gtcaagttga
    18541 tagttttcaa aacagttttc ccttgataag cggctgaaag gtcttgaatt acaatggccg
    18601 tacgttccaa atcttacact cctttttagg tttacctaac tttttattta aatatagttt
    18661 aactaaaatg gaaagcattt tcaagtagaa tgatgaaaaa gtttttttcg aattttcctc
    18721 gcattttatg aaaattttct gtagaatcac atcaagagtt caataaggct aacctaataa
    18781 tgaaaaacat gtgttgaaac gtttgattat tttttcttgt tgactcaaca acgaaaggag
    18841 tttttgtatg gaagaagaaa agttaactcg aagtcttagt gcccgtcata tccaaatgat
    18901 cgcactaggt ggaacgatcg gtgtcggtct gtttatgggt gcctcctcaa ccatacgttg
    18961 gacagggccc tcagtgatgg gagcctatgc gattgcagga ttctttttgt atttgattat
    19021 gcgtgcttta ggcgaaatgc tttacgttga tccttcgact ggttcttttg caaattacgc
    19081 gagcgagtac atccatcctg tggctggcta cttgaccgct tggagtaata tttttcaata
    19141 tattgtcgta ggaataagtg aagtgattgc tgtaggatct tatatgaatt attggtggcc
    19201 tgatttgccg gcaattattc ccggaatcat tgtcgtcttg tttcttatgc tggcaaatct
    19261 tatttctgtc aaggcgtttg gcgaattaga attttggttt tcgatcatca aagtcataac
    19321 gatcattttg atgatcattg caggtcttgg ggtaatctta tttggatttg gtaatcatgg
    19381 tcaggcagta gggatttcaa atctttggaa aaatggtgga ttcttcactg gaggcgtcaa
    19441 aggatttttc tttgcattat cgatcgttgt tgcttcctat caaggaatcg aactgatcgg
    19501 aatgactgct ggtgaagcag agaatcctaa aaagacgatc attgaagctg tccagtccac
    19561 tatcggtcga atcttgattt tttatattgg tgctattttt atcattgtga gtatctatcc
    19621 gtggaatcaa ttgagtgaga ttggttcacc ttttgtacaa actttttcta aagtcggcat
    19681 tacatttgct gcaggactga ttaattttgt cgtgattaca gcggcattat caggttgcaa
    19741 ttcagggatt ttcagcgcaa gtcgtatggt ctatacactt gccataaatg gaaagatgtc
    19801 taaaaaattt ctgaaactat ctcgtcacgg tgcgcctttt tatcctgtcg tagcaatctc
    19861 aggtggaatc ttaattggtc tgatcttaaa ttatcttcta ccaatgttca tcaaccagtc
    19921 agaaaatatt ttcgttttcg tatacagctc aagtattttg cctggtatgg ttccttgggt
    19981 agtgattttg atcagcgaga ttcgcttcaa aaagaagcac gcagataaaa tgcatgatca
    20041 tccttttaaa atgccactat ctccttatac gaattatgtg acacttgctt ttttagctat
    20101 cgtattgatt ttcatgttta tcaatcctga aacgagaatc tcattgatta ttggactcgt
    20161 tttcttgctt tacatgacga tccattactt tgtacgcgaa aaaagaaccg gaaaataaaa
    20221 aaagaacgaa gcttcacctt agtggaagct tcgttctttt ttattgcttt tatcaattca
    20281 attttagcgt ctcaccggga gtcaggaaat aattctccat gctcatccca ttcagcgaca
    20341 agatcgtttc tactggtacg ccagttcgtt cggctatttg atttggacct tctccttcca
    20401 aaactacggt tgtcgcagcc tgtgaagtcg cgctgttggt attagtttca gaggaatctg
    20461 ttgtgtcttg tgttgttcga gcttgcattt cagaagcttc taccgactct gctgtctcag
    20521 aatcagaaga tgttgtgtct tgtgtgcttg ttgactctgc ttgaagagag gcgctagtct
    20581 gcaaataaat atcggaaatc ttagcgacat gattcgtata attagccgat aattgattga
    20641 tcaaagtatc taagtctaca ccgtctttat tttctgctgc ctgatacgct gcacgtaatt
    20701 ttctgatccc ttcgtcggag attgcttgaa gctcacgtgc tttttggtta gcaactgctg
    20761 ataaaccagc tattccctct tgatttccct gaatttctgt ctggtattct tcaatcaatg
    20821 caggcgtctt ttcttcgatc tttttcgaat aatcatttac gattgcttga agttgctctg
    20881 gcaaaccatt tgctgttttt tcttcagaag tttgtgtctc ttttgtttta gttgatgact
    20941 cacttgtttg tttcgtctct gttttctttg tcgttgtttc cgttatggtc gtacttttcg
    21001 cttctgacga attttttcca tgaaaatata gacccgcaac tcctcctgct atgatcaaaa
    21061 acacggcaac tgctgcccca atcatgatca tccgcttacg agctgcctgt ttttgctgtc
    21121 ttcttcgggt catccgaaca ttttctcccc actcattttc atcatacatt tttttcacca
    21181 ccaattttta tgtataatag cgttatcaaa cgcttcatat tcttattgta gcaaataatt
    21241 gtcgctgtgc acatttttat ctttgttatt tataagaaaa tttcaccagt tgagatgatt
    21301 ccaagattgt ccgtcgattt ctccttgcag ctgcattgtt cgttcgtcta tctcagccat
    21361 cagtttcttt atttcatata agagcgcacg gtcttgatat tctgattttt cgcttaattc
    21421 atctaattgt tggatcagcc aatcatttgt cataatgaag ttcctttcat ttcttgcagt
    21481 gtaaaggtca agtcttcgat ctgctctttt gcctcagtca gtgcttctac gatatatgct
    21541 tgtttttcag attcttcttc ctgcattttc tgattttcct gtactctttg aataaaccag
    21601 tcaatccgct gagtcagcga tggtttgcct tccaatgaga gatactgctg ataagcaatt
    21661 agcttctccc aacgtttttc ctgggataaa tacataaatt gtgctaaaac gaatggcgga
    21721 agataggtca tatggaattt atttgcgatt cgctgatacg gcctcaaaaa ttcggaaatc
    21781 gtatattctt cttttcctcc agcttggtat tctttttccg ccacacctgt tgtcaatacg
    21841 attcctagtt ctttcccttt taatacatgt gctgctcgtt ccaagacatt atcttgccaa
    21901 atttttaaat gagcaggaga actataccag taaaacggaa actggaaaat gatccgatca
    21961 tgctgggcca agagctgtag ttcagtctct atatctattt ttccgtctgg ataacttgat
    22021 tccaaatgat gccaagtagc tggtaaacca gcagaagctt ctttgaaaaa ttgctgattt
    22081 aaagattctt cgatcgttgg atggctaatg atgataagtg tacgcatccc ttttcctcct
    22141 ttttagtctt cgctttacag tgtagcataa ccgccacaag tttcttttgc cgatgcttgt
    22201 cattttaacc agactaatca ggttgtccaa gaaactgcgg tttgtttttc caactgtttt
    22261 ttcaaggtat ccaaagcaat attcttaaaa ttttcgtttt tcatacgttt acgatagttc
    22321 gtagccgttt ctccggtact ctttttgaac attcggctaa atacgactag actattgaac
    22381 cctacttgat aggcaatact ttccacggat tcatccgtca gagaaagaag aaacgcccct
    22441 cgattgatcc gtaccccgat caaatattcc ttgatactgg tacccatatg atttttgaat
    22501 actcgcgaca aatggctccg attgaccgct aaatgctggg cgatttcctc aacagacaat
    22561 ttttcagcat aatgtgcctc gatgtatttg actgtttcaa cagctaaaga ggaatgaacc
    22621 ttttgtacac caccgctgac ctttccgcca tcttttaaaa ggactgataa aaaacggtag
    22681 gttaatgctg ttaactgtaa ttcattttcc aaggtttctt ccgtatcttt catgcattct
    22741 aaaataatgt cgatatattt ttgtatgtca gaagagacca tcgtgtattg gtcttctctg
    22801 aaaagcgact gccgaatgat ttcttctgca gcactcccac caaatgaaag ccagcaatac
    22861 atccacggat cttctccatc tgataagtaa aacgtcgagt ctcctggacg aatcaagaac
    22921 agatcacctt ttttcaattg gaattgttga tttttcacat gataagatcc tttgccttcc
    22981 atcacgacat gcaggatgta atcattgcga atagcaggac caaaagaatg aaacggcatc
    23041 gttttagaga aaccacaaaa atcaaaatac aattcttttt ctacttgttg atgttccttt
    23101 tttaaaaaaa tcgattgctc cacgtctatc cctccttact cctttagtat aatgcaacaa
    23161 aaagttaaat aaaagtcaca gaaatatatt aaaaaggaag cgatttcttg ttaagtttaa
    23221 gtcattaaaa gatctttgtt attcgttgta accggtttac ttagtattat atattgaaca
    23281 ggagaggaat acagattatg aaaagcaaaa tgatccaacg tgtgtcctac gctttaggcg
    23341 cttttggaca cgacacattc tatgttacat taagcactta ttttatggta ttcgtgacaa
    23401 gccagatgtt cgcaggaaca gataaggcaa cgaatgcaaa aatgattgct acagttacaa
    23461 gcttagttgt aggtatccgc ttagttgaaa ttatttttga tcctttgatt ggtggcatca
    23521 tcgataatac tcgtacaaaa tacggtaaat tcaaaccatg gttagttatc ggcggcgttg
    23581 ttagttccgt actcttggta gcaatcttta ccaatttctt tggcttagct actcataata
    23641 cgactttatt tatcatatta tttgcaatcg ttttcatctt attggatagt ttttattcat
    23701 ttaaggatat cgctttttgg tcaatgattc cagctttgag tacggaaaca aaggaacgtg
    23761 aaaaatttgc tacgtttgct cgtttcggct cttctctagg tgcaaatggt actactctag
    23821 tcgttgtccc tatcgttact ttctttacct atcttgttac tcataaacat attgaaggcg
    23881 cttcaggctg gttctggttc ggtgtgattg ctgctgttat ttcaggcggt actgcgatta
    23941 tcactgcctt gggcacaaaa gaagtcgata ctgcgatccg tcagcaaaat gaaaaagctg
    24001 ggatcaaaga tgtgttcaaa gcagttgctc aaaatgatca gttgatgtgg cttgcccttg
    24061 cttatatcgc ttatgcgatt gccaatgcag caacaactgc cgtattattc tacttcttca
    24121 aatatgtact tggccaacca actgaatttt ggatcgttgg tctagttgct gccttacttg
    24181 gtttagtagc tgttccacta ttcccaatgc ttacacgcgt catctctcgt cgctacgttt
    24241 accttggagg gatcgcaatg atgatttctt cttacttttt ctttacgatc gcaggttcaa
    24301 gtttgccaat cgttatcatc gggctagtat tgttctactt ccctcaacaa ttgattttct
    24361 tatccgcttt gatgacgatc acagactctg ttgaatatgg tcaatggaaa aatggtatcc
    24421 gtaacgaagc tgttactcta tcaattcgcc ctttactaga taaaatcgct ggtgctttgt
    24481 ctaacgggat cgtagggttt gtcgctatcg cttctgggat gactggtaat gctactgctg
    24541 ctgatatcac tgctcatggc gtaacgactt tcaaagctta tgcattctat gctcctgctg
    24601 ctttgatgat tttctccgct attatttttg cttggaagat tacattgaca gagaaaaaac
    24661 atgcacaaat cgttgagaaa ttggaaaaca aattggctcc agctgataca atggaagatt
    24721 aacttcacga tgcagtagtt ccttcccatt aagaaaggat cttgaaaatg aagattacag
    24781 aaaaagattt tggccaaggt tatcacttga taaccttgga gaacaaaaac aagctagcac
    24841 tttctatctc tgatttaggt gctagaatcg tcagtttaaa atcaaatgat cgagaattag
    24901 ttttgggatt tgacaccgct gaagaatata tcgaaaaaga tccgtatatc ggtgcttcta
    24961 tcggtcgcac cgcagggaga atcgaaaatg gccgcttttc tctcaatgga aaaacttacc
    25021 aattagccac agatccaaaa actggacata atctgcatgg tggtgctcct ggatttgaat
    25081 taaaaaaatg gtcttatgtc attttgaatg gcgaaaatga agcttctgtc atttttacta
    25141 ctacaagtcc cgacggagaa catggttttc caggtacaat ggatgtggaa atccgctata
    25201 ctttgacaaa agataatatc tggcgagtga cctctcgcgg caccagtgac caagatactt
    25261 tattcaatcc gacaaatcat gtttacttca acttgacggg agatgcttct cagtcaatcg
    25321 atcaacatga gctttggctc aatagcgaag cttatgctcc tttgcgaaca gatagtattc
    25381 ctataggggt aaaagaaaat gctgcaggaa gtgctttcga ttttcaaata cctaaaaaat
    25441 tagcgtccgt ttttgctagt gatttggatc aaaaaaatct tgttgacgga atcgatcatc
    25501 catttttctt aaaagaaacc ggcttgggta aagaagccgc tcgcttgact agccccgata
    25561 aaagaatcca agtagatatt gctacagatg cttctagtgt ggttattttc actgcaaatt
    25621 tcggcacaga aacaccagaa atgcgcaacc gaaaactggc acatcacggt ggcatcacat
    25681 ttgagactca aacagctcca ggtgcagagc gcttctcagc atttggttcg attcatttaa
    25741 aagccggatc agtatttgaa acagtaacag aattcaaaat caaaacaaga aaggaataac
    25801 tcatcatgga aatcaaaaga agcttaaaca caaaatttgc cgaaacattc ggacctaaaa
    25861 aaactacaca atacttctca ccaggacgca tcaatttgat tggtgaacac acagattaca
    25921 atggaggcca tgtcttcccc gcttccatca cttatggaac gcaaggtgta gcagcacctc
    25981 gagacgataa taaaatatta gtttattcca caaactttga cgatatcggt gtcattagtt
    26041 ttactttaga tgagctagaa tatgataaaa aagcaaactg ggcaaattac gtaaaaggaa
    26101 tggtccttaa attaaaagaa gctggacact caatcgatca tgggtttgag ttattagtgg
    26161 aaggaacaat ccctaatggt gcaggacttt ccagtagcgc ttcattagaa ttattagtag
    26221 gtgttgtatt agaagatctg tttgatttaa aaacagatcg cttggaacta gtccaaacag
    26281 gtaaaaaagt agaaaatgaa ttcatcggtg tcaattcagg tatcatggat cagtttgcca
    26341 tcggcttcgg tgagctagat catgcaatct tattagatac aaatacgctg aaatacgaaa
    26401 tggttccagt gaaactagat ggttatgcaa tcgtcatcat gaatacgaat aagcggcggg
    26461 aattggcaga ttcaaaatac aatgaacgcc gtagcgaatg cgaagaagcc ttggcacgtt
    26521 tgcaaaaaac tttgcctatc tcttctttag gagacttaga tgaagaagaa tttgaatcaa
    26581 ctattgacca aatcggcgat gatacattga tacgcagagc tcgccatgcc gtttctgaaa
    26641 atcagcggac tttgaaggca aaagctgaat tagaagctgg gaacttagaa gcatttggtc
    26701 aactgttaaa tgattctcac cactctcttc gctatgatta tgaagtaact gggatcgaat
    26761 tagatacact agtagatgct gctcaaaaac aagaaggtgt cttaggtgca cgaatgacag
    26821 gagctggatt tggtggctgt gcgattgctc ttgtcaaaga agaaaatata cctgccttca
    26881 aaaacaatgt ctatgatgaa tacatgaaag ttgtcggcta tgctccggaa ttttatgttg
    26941 cacacattgg aaatgggaca acaaagatcg atccagaagc tgttcatgtt tgataaaaaa
    27001 atcaacgatc tcagctaaaa acaaatagat aaaaataacc tctcagcaat ttccaaatgt
    27061 gagccttttg ctcgtatttg aaaattgctg ttttttattg acacggaaag agaacgtgtg
    27121 ttctaattgt gttgaagagg tgattgttat gtgggcgaat caaaatccgg tatttgttta
    27181 tgaaaaagaa ccttcaagag atattttatg tattgactgc aaatcttttt acgcctccgt
    27241 agagtgcgtt gaaaaggatc ttgatcccct tacaactaaa ttagtagtca tgtcctatcc
    27301 gtccgattcg acagaaacac ggggtagcgg attaatcttg gcttccagtc ctgcagcaaa
    27361 aaaagcttac ggcatcacca atatcagccg tgccagagat cttcccttcc cctatccaag
    27421 tgatttatat attgttgccc caaggatggc ctattatatg gaaaagaaca gagaaatcaa
    27481 ttctatctat aaaaaatatg cagacgaagc gaaccatcat gtctattccg tcgatgaaag
    27541 cttccttgat gtaacaaata gcatggcact ctttggtaaa acaaatgcgt acgacatggc
    27601 taaactgatc cataaagatg tgtttgagca gaccggaatc tacacgacta taggaattgg
    27661 cgataacccg ctacttgcta aactagcctt agacaatggc tcaaaagacg gaaagcaaat
    27721 gtttgctgaa tggcgttatg aagatgtacc agaaaagtta tggaaaatct cagatatcac
    27781 tgacttttgg ggaatcggca aacgaacagc aaaacgtctg aaacaaatgg gtatacattc
    27841 tgtttatgat ttagctcacg cggattatta tcacttgaaa agcaagctag gggtcatcgg
    27901 tactcagctt tatgcccatg cttggggcat cgatcgaagt tttttgggac aagaatatac
    27961 accaaaatca aaaagtatcg gaaatagtca aatcctagat agagattata caagacgaga
    28021 agaaatcgag atcgttatca aagaaatggc cgaccaagtc ggcactcgct tgagacgatc
    28081 tgcagcaaaa acacaagtag tcagcttatg ggtaggatac tctttaggct atcttgatcc
    28141 aaatggcaag accgggtttc accagcaaat gaaaatcgaa gcgacaaatg ctagcagaga
    28201 tcttgcagat gctttattga ccattttcca ccagcattac cactaccagg atattcggcg
    28261 tgtaggcgtg aactgttccg acctcgtata cgcgacaggt ttacagctta acctttttga
    28321 agatcctgaa aagcagataa atgaagcgaa agttgatttt gttgtcgata cgattagaaa
    28381 aaaatacggc tttcaatcaa tcatccatgc gcatagtctc ttgcaaggag gacgcgccat
    28441 cgcacgtagt tctctcgttg gcgggcatgc aggtggtatg agtggattag aaggtggaaa
    28501 agatgagacg gacagcaaaa aaattcattg actataacga gtatcgagat cggccatttg
    28561 gattaaaatg ggggactgct tttgcgatgg aagaactagt caacggtatc aaaaaaatga
    28621 agaagaagca cgcaaacagc ctcttcctaa acaacaaatg acattgcaag aaatcgatag
    28681 tatactgaca gaagcctttt tatctcgtaa agcagtaatc attcagctca atttaaaaga
    28741 tgaatttgga agactcttgg atgaggtcga agggcacttc attggtgaag cctatgaaga
    28801 ttactttatg attgaccatc agccgatatt gtgggaagac gtacggtata ttgagttaaa
    28861 ggaaacaaaa aaatggtttg tgacatgaga ggttgtgaca gaagtgatca acttcaaaaa
    28921 ataagaaagg atttttcgaa aattgcttct taaatttttg tggaattttg gcttattttt
    28981 cgaagaagca acttctggaa caacgtatat tagatatcag aggttgtgaa aaagtcgctt
    29041 agttttgagt aacaagccaa ggcgctgatt tcacaacctc tgtctatcta tccatctatt
    29101 cggtaagatt catgcatgac gtcttcttta tttagtatgt agagcccttt ttcttctgac
    29161 cattcaacat aaatcagctg ttttacatct gcatagcctt ctttcttcaa gttctccata
    29221 agccatgctt cagtcaattg attggactga agcactttat gctgaatttg cccttcatct
    29281 acaagcagga tcgataaagc tttgtcttca tctgattttt tcaatacact catttgaccg
    29341 gcattctcta ggataacatg tttggcattt tcaagaaaaa agcattcttg ctgtcttaag
    29401 attgctcgca actgctccat ctcgatatgg ttatttgtca actctgtcat gttgatgacg
    29461 ccgtctttga ttagaacaga tggctcgcct ttgacccaac gattgacctt ttcatttttt
    29521 tggacgatac gttcgatacc ataaatcatt actgcccaaa gcgcaatggc aaataggaca
    29581 tgccctacat ggacattgtc atcataggtt gattcttcta agatcccacc taaaacaagc
    29641 gtatagacta aatcaaacgg tgtgatttct gacatggatt tcttcccaag caaacgtacc
    29701 actaataata aaccgatcaa cccgaacacc agtttcattg taattgaaaa aatcattttt
    29761 tctcccccta actatctgtt aattaaatta tatatgcttt ctcacgaaca cgcatggaat
    29821 atacaaggaa gaaatgtatc cttttactaa aaaaaggact gtgacactgt agtgaccccc
    29881 aaaagttaga cttttttgga gtggagaaat ccactccttt tttttatgct ctaaaatgat
    29941 atttttacac aaccgttacg gttgttttac gaaattggac g
//
LOCUS       DAZKKZ010000034        29110 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.034, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000034 DAZKKZ010000000
VERSION     DAZKKZ010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 29110)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29110)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29110
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.034"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..1031)
                     /locus_tag="ACG8LA_001612"
     CDS             complement(<1..1031)
                     /locus_tag="ACG8LA_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFQ0203915.1"
                     /translation="MKSNEKTPLTTSLILLLSITCGVVVANMYYIQPIGTKVAASLSV
                     STSAVGILTMLTQLGYALGLLFLVPLGDVVDRPKLIIRMVALSAVSLLAAFFAPSFTL
                     FACASFLIGLLSIVPQIIIPYGAVLAGPKARGKVMGTLLSGLLVGILLSRTVSGIVAS
                     LFSWRMIYLFALCAVGILTLLLYWKMPRSVQQSSTAVSYLDSLKSLPHLVASQRLLRE
                     AAVSGFFMFGTFSIFWSTLIFYISSPAYNWGTFEAGILAIFGLSGAVAAPIVGRLADS
                     YSERKIVYMGLVMQTISFIALLVGGSHLAILLLAIILLDVGNQFGQVANQTRVQGLGE
                     AASNRNNTV"
     gene            complement(1113..1802)
                     /locus_tag="ACG8LA_001613"
     CDS             complement(1113..1802)
                     /locus_tag="ACG8LA_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VTT domain-containing protein"
                     /protein_id="HFQ0203916.1"
                     /translation="MKKKIIRLMLISLGIILILVVGYRLYLEYQTDIQLFLNPRASKA
                     ELLAHIRSHGTFASILLIVLTAVMCAVPGIPTSVVGVIAGLSFGPLTGAIINILGNAL
                     GNITAIFLMHRLKFLDKKTETNHWVQAIRQMKHPKIGVMLGYMIPVIPSSMVNFAADA
                     MKLPLQQIILSIVIGVIPSSVLYACGGEALFHGYNKTAVTLVASVTVLVGLVVFIYKD
                     RKKKQGKQKHK"
     gene            complement(1908..2276)
                     /gene="rplL"
                     /locus_tag="ACG8LA_001614"
     CDS             complement(1908..2276)
                     /gene="rplL"
                     /locus_tag="ACG8LA_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HFQ0203917.1"
                     /translation="MALNIENIVAELKEATILELNDLVKAIEEEFGVSAAAPVAVAAA
                     GGAAAAEEQTEFTVELTAAGDQKVKVIKAVREATGLGLKEAKAVVDGAPAPVKEGVSK
                     EEAEELKAKLEEVGASVTVK"
     gene            complement(2329..2832)
                     /gene="rplJ"
                     /locus_tag="ACG8LA_001615"
     CDS             complement(2329..2832)
                     /gene="rplJ"
                     /locus_tag="ACG8LA_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HFQ0203918.1"
                     /translation="MSEAIIAKKAAIVDEVSEKFTAAASVVVVDYRGLTVDEVTRLRK
                     QLRDANVEMKVIKNSILSRAAKKAGLEGMDEVFTGPTAVAFSNEDVVAPAKIMDEFAK
                     EAKALEIKGGIIEGKVSSLEEITALAKLPNREGLLSMLLSVLQAPVRNVAYAVKAVAD
                     KEDGDAA"
     misc_feature    complement(3036..3163)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            complement(3242..3931)
                     /gene="rplA"
                     /locus_tag="ACG8LA_001616"
     CDS             complement(3242..3931)
                     /gene="rplA"
                     /locus_tag="ACG8LA_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HFQ0203919.1"
                     /translation="MAKKSKKMQDALKKVDSSKVYPVAEAVALAKETNIAKFDATVEV
                     AYRLNVDPKKADQQIRGAVVLPNGTGKTQTVLVFAKGDKAKEAEAAGADFVGDDDMVQ
                     KIQNGWFDFDVVVATPDMMATVGRLGRVLGPKGLMPNPKTGTVTMDVTKAVNEVKAGK
                     VTYRVDKAGNIHVPIGKVSFDDEKLVENFAAIHDVLLKAKPSAAKGQYMKNVTITTTF
                     GPGIHVDQASF"
     gene            complement(4035..4457)
                     /gene="rplK"
                     /locus_tag="ACG8LA_001617"
     CDS             complement(4035..4457)
                     /gene="rplK"
                     /locus_tag="ACG8LA_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HFQ0203920.1"
                     /translation="MAKKVEKIVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGLIIPVVISVYEDRSFTFVTKTPPAAVLLKKAAKIEKGSGEPNKNKVAKVSS
                     DQVREIAELKMEDLNAANVEAAMRMVEGTARSMGITVE"
     gene            4800..5468
                     /gene="sdaAB"
                     /locus_tag="ACG8LA_001618"
     CDS             4800..5468
                     /gene="sdaAB"
                     /locus_tag="ACG8LA_001618"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003941 - L-serine ammonia-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA];
                     GO_process: GO:0006565 - L-serine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HFQ0203921.1"
                     /translation="MKDLRYRSVFDIIGPVMIGPSSSHTAGAARIGKIIRSIFGEQPD
                     SVDIYLYESFAKTYRGHGTDIALVGGLLGMEPDDERLADSLKLAYEAGMEVLFVPKSE
                     KAEHPNSVKMLLKKGTRKLSVTGISIGGGNIQISELNGFKISLSMGTPTLIVVHQDVP
                     GMIAKVTSILSETNTNIGTMTVTRESKGENAIMIIEVDDPQVEETVKRLKQLPNIDSV
                     NYFD"
     gene            5481..6353
                     /gene="sdaAA"
                     /locus_tag="ACG8LA_001619"
     CDS             5481..6353
                     /gene="sdaAA"
                     /locus_tag="ACG8LA_001619"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003941 - L-serine ammonia-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA];
                     GO_process: GO:0006565 - L-serine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HFQ0203922.1"
                     /translation="MFLSIEELVDQAKAYPSVAELMIAVEMEMSGRSRSHIIEIMEKN
                     LSVMEQSINEGKEGVTSVTGITGGDAKKLDDYLNEADFLSGETILKAVRNAVAVNEVN
                     AKMGLICATPTAGSAGVVPGVLMAVRDRLDLTHEQQLEFLFTAGAFGLVIANNASISG
                     AEGGCQAEVGSASAMAAAALVCAKNGTPHQAAQAVAITLKNMMGLICDPVAGLVEVPC
                     VKRNALGSSQAFISADMALAGIESVIPPDEVVAAMYQVGRQMPSIFKETAEGGLAVTP
                     TAKRLAEEILNKRA"
     gene            complement(6444..7544)
                     /locus_tag="ACG8LA_001620"
                     /pseudo
     CDS             complement(6444..7544)
                     /locus_tag="ACG8LA_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324221.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
     gene            complement(7636..8523)
                     /locus_tag="ACG8LA_001621"
     CDS             complement(7636..8523)
                     /locus_tag="ACG8LA_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HFQ0203923.1"
                     /translation="MTEPIKNLCKRATAAALVLISLFALSGCQTTKINTTEVSDKEKT
                     AESSKVIEKTTIPTLFFHGYSGTENSFKGMLRRLEKNQQAVKELVLTVGTDGQIQATG
                     DLSGKADNPMVQVLFEDNKNNEWNQAEWIKTCLLYLKENYGIDKVNIVGHSMGGVSAL
                     RYLGTYGQDTSLPQVQTLTAIGAPFNDFVDDSAQSLTDELAKGPAVVSNRYQDYQQMI
                     GNIPITTRFFLIAGQLDETDLSDGTVPLNSALAVYALLKQRGNEIEEKVVTGENASHS
                     MLHENQEVDQLVSRFIWKE"
     gene            complement(8600..9145)
                     /gene="nusG"
                     /locus_tag="ACG8LA_001622"
     CDS             complement(8600..9145)
                     /gene="nusG"
                     /locus_tag="ACG8LA_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0032784 - regulation of DNA-templated
                     transcription elongation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HFQ0203924.1"
                     /translation="MESFEKNWYVLHTYSGYENKVKANIESRAQSMKMADFIFRVVVP
                     EEKETEVKNGKEKEIVHKTFPGYVLVEMIMTDASWYVVRNTPGVTGFVGSHGAGSKPA
                     PLLPEEVNHILRSIGMSLRQNDLEVEVGEVVKIIEGAFAGLEGQVTEVDGEKEKLKVN
                     IDMFGRETSTELDFDQVDKID"
     gene            complement(9246..9416)
                     /gene="secE"
                     /locus_tag="ACG8LA_001623"
     CDS             complement(9246..9416)
                     /gene="secE"
                     /locus_tag="ACG8LA_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HFQ0203925.1"
                     /translation="MKFLKSVKDEIKQVTWPSRKQLRKDTLVVIETSIIFGLMFYVMD
                     TAIQSLFGWILK"
     gene            complement(9440..9592)
                     /gene="rpmG"
                     /locus_tag="ACG8LA_001624"
     CDS             complement(9440..9592)
                     /gene="rpmG"
                     /locus_tag="ACG8LA_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HFQ0203926.1"
                     /translation="MAKKKAALACSVCGSRNYTKSVSEGKSGERLEINKFCKYCNQYT
                     LHKETK"
     gene            9754..10398
                     /gene="cbpA"
                     /locus_tag="ACG8LA_001625"
     CDS             9754..10398
                     /gene="cbpA"
                     /locus_tag="ACG8LA_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic di-AMP binding protein CbpA"
                     /protein_id="HFQ0203927.1"
                     /translation="MLLKTLVYKKKDLTTVTETSTLEEALKILETSGYRCVPILDSSG
                     NIFRGNIYKMHIYRHKANGGDMTLPVTHLLKNATKFIYLDTSFFKVFFTIKELPYIAV
                     LDSENHFYGILTHSTLLNMLSQSWSVEQGSYVLTIASTGKQGDLAAIAKIISKHSSIA
                     SCITLDIEKDEYIRRTLITLPANTEAKVCETIVNHLEKKNYKVVEIENLQNQEA"
     gene            complement(10454..10957)
                     /locus_tag="ACG8LA_001626"
     CDS             complement(10454..10957)
                     /locus_tag="ACG8LA_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HFQ0203928.1"
                     /translation="MQKTKSRQRLSVIVVNGIIMALYLALTILVAPVSSGPIQFRISE
                     SLNHLVVFNRKLLWGVLGGVIVYNAFFGFGIMDVVFGGGQTLLSLGLTALLQNKVKNV
                     KMRLVLNTIFFTISMGLIAYMLVPTGGQAFWTTYGTLALSEFIVMAVSAPLMYYLDRA
                     LDFEKRV"
     regulatory      complement(10970..11016)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            11554..12519
                     /locus_tag="ACG8LA_001627"
     CDS             11554..12519
                     /locus_tag="ACG8LA_001627"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HFQ0203929.1"
                     /translation="MKFHYHILINPSAGSGNGYKVAERILPVLKNKHIDYTLHYSEYK
                     GHDAEIAETLAKETLIPWIEEEQKTIDTFPLLIIVGGDGTLHQVLDTFYQMEVEFPVA
                     YIPAGSGNDFARGAGLPKNPKKGLQLILAAQSPEKVHIMAYEEKISEKKGIAVNNFGI
                     GLDAAIVHATNHSSTKKRLNKYNLGSFSYLFSILRALFTQKGFPILVDAGGKQLSFSN
                     AFLCTATKHPFFGGGIAIVPTADASKPVIDFVVVERINFFKILWLILLLIQKKQLKSK
                     YFHHYTTNRLRIVSTTPQHGQEDGEEMEKRPFDITITTTKQLFWC"
     gene            complement(12618..13790)
                     /locus_tag="ACG8LA_001628"
     CDS             complement(12618..13790)
                     /locus_tag="ACG8LA_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFQ0203930.1"
                     /translation="MTLYKTIWTLLKANKSNLLIGVIITVVATFFFAQNIDVENTSLQ
                     DAKIALISEEESPVVDGLRKYLNDKETVVTLDGTSQKEIDDALYFNRVNIILHLPADF
                     TEQVEVGKMATIKIQSRPDAFSKTVVTQQVNTFLQTLILFQEEDKTIDAAMEQTQMAL
                     SVTGEVELSAGYSQRMKKLLTGTTFNFLSYGLFLSIFSGFSVINLAFNRKEISKRNQS
                     APITKRNLNRKVTFSLISYSLLLFSGFLLLMVLLVIHTSWDITVWYHILNTFLFLLPI
                     ISFSACITSLVKNSETSGGIKDIFITGSCFIGGVFVPAEYLPEMVSKIAAFTPTYWFV
                     QNNNLISETLSYNQTFAESFWFNGCVLVAFAAVFSMIQFILGKERNYRWQPNWAKN"
     gene            complement(13777..14922)
                     /locus_tag="ACG8LA_001629"
     CDS             complement(13777..14922)
                     /locus_tag="ACG8LA_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFQ0203931.1"
                     /translation="MFWHFYKYRTKILLRNKSMLFWTLAFPILLGLMFMAAFGEIDQG
                     GNLETINTGIVIKADQTALSENFTTVLEQVEVNDKPLFEVQELSEVEANEKLNADDLA
                     GFYLIDGSSVSLHVGQAGMSQTLMKNVMDQFLQRIGIISSKVAEVENVDLAPIMTVFE
                     QEVSFQEVHAGRNMSFKSFYFFTLIGMAILYGTMWGVRNVQDQQANQSSNGIRLSLIP
                     RKQSLVSIANLAASFTIVLTEIYIMLAVFRFIYQVDFGERWQWLMIVTALGSLCAILL
                     GTLVGNLIPKMNLVQKDSILISVTIAMSFFAGMMGSEQVKYWIDLHIPIVGQLNLVNL
                     ISESLYKLYFYTDLASFYTNLLWLIGFIFLFALGNAWMERGVRYDAL"
     gene            complement(14936..15868)
                     /locus_tag="ACG8LA_001630"
     CDS             complement(14936..15868)
                     /locus_tag="ACG8LA_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0203932.1"
                     /translation="MIIEIDKLVKRYGDFVALNHFDLQVQEGEVLGLLGPNGSGKSTA
                     INCMLSLLNYDKGTIKLFGTTMTPENYAVKAMIGVVPQDVAVFDELSVQENIDYFCGL
                     YVSEKEKRKALIEEVIQLVGLEKYVSFRPGELSGGLKRRLNIACGIAHKPRLIFLDEP
                     TVAVDPQSRNKILESIKELNRQGATIVYTTHYMEEVEILCDQIVIMDQGQVIAKGTKE
                     SLKDMVRTADRLTIDIPLLPENVLSAIQRTIASDGIAYKKGQLQVTTTELNTVLLPIL
                     TILQEEKISYGKIATKEASLNDVFLEITGKDLRD"
     gene            15985..17064
                     /locus_tag="ACG8LA_001631"
     CDS             15985..17064
                     /locus_tag="ACG8LA_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HFQ0203933.1"
                     /translation="MHKSRLLNETSFLLVISLLLLVSQGFVAMQVIYLLIAVLFTGVS
                     YLLPTKPNWIFQVILFLLCAFLPDLVLFLPATMRVIAPEESHLDYLFLLGFLLISTVG
                     NHPPIKVAFVVILLFFSFYLRKKDQRTTDLEKKYIVSKDTHWEKQQELSEQNKALALS
                     QETQLALQIVEERNRIARDIHDNVGHLLSSAILQIGALEMINQEPKLKEPLENLSATV
                     HTGMDRIRQSVHDLHETSISFQHSLEFLIADFPSSVTIEGNLFEGLNETQQNCFLMVI
                     KEALTNSIKHSHAKTVVLHFRTLPAFYRLQITNDGTSPQKNSAPGIGLKTMRQRVQEQ
                     KGQVHIFQENQQFQLTIILPREGHQ"
     gene            17061..17690
                     /locus_tag="ACG8LA_001632"
     CDS             17061..17690
                     /locus_tag="ACG8LA_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFQ0203934.1"
                     /translation="MITVVIIDDDPFVTKSLQTILESTKEIRVLGIGHCAKDALVLYE
                     THRPDVLLTDIRMPKQTGIDAAKEILAKFPKAILLLLTTFKDEEYIREAFSIGVKGYL
                     IKQNLQAIIPSVKSAYNGQAVFGNEIIETFTQMMKNKPTIDSHAYASFSERELAIIKE
                     VAAGKNNKEIADALYLSDGTVRNYISQLLEKLDLRDRTQLAIYFYQHLQ"
     gene            complement(17800..18027)
                     /locus_tag="ACG8LA_001633"
     CDS             complement(17800..18027)
                     /locus_tag="ACG8LA_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HFQ0203935.1"
                     /translation="MAKETEDKLAKLAKESGNDFKKLDEMEKEFKLNESPDVERDDRE
                     ESKLEKTLDKAPIFPPNTPNNPTNPGSPANP"
     gene            complement(18130..20718)
                     /locus_tag="ACG8LA_001634"
     CDS             complement(18130..20718)
                     /locus_tag="ACG8LA_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0043139 - 5'-3' DNA helicase activity
                     [Evidence IEA];
                     GO_process: GO:0032508 - DNA duplex unwinding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HFQ0203936.1"
                     /translation="MQPEEMPYFVGTVAAIFFQNPSNFYKVLLVHISETTADYREKEI
                     VVTGSFGDIQENETYRFYGELVDHPKYGRQLKLERYEQEKPTTANGIVAYLSSEKFPG
                     IGKKTAEKIVELLGEDAIEKIIADPSVLKQISGLTKPKREMLAETIRLNHGMDQVIMG
                     LNRYGFGSQLAFSIYQAYKNESLDIIEENPYQLVEDIEGIGFKRADNLAEQIGIAADS
                     PRRIRAAILHQIFQHAVQTGDTYVPAETLLQQTIRILETSRPIEIQPDQVATVIIQLV
                     EEGKIQQEETNLYENSLYFSEWGIGNSIQRLLSRKKEIHYPEKEVQKNIRRIEKIFGI
                     QYGPSQEQAIAEAIRSPLFILTGGPGTGKTTVINGIVNLFAELNGLELDPSKYTQEIF
                     PILLAAPTGRAAKRMNETTGLPASTIHRLLGLNGREKTPSVSTKELEGGLLIVDEMSM
                     VDTWLANTLFKAIPTNMQVILVGDKDQLPSVGPGQVLHDLLEIEQIPKMELNQIYRQG
                     DGSSIIPLAHEIKEGRLPKDFTKNQKDRSYFRSDAYQIEPLISKIVEKAKNKGFRAQD
                     IQVLAPMYRGPAGIDALNKMMQEIFNPGKPGKKEVHWNDTVYRIGDKVLQLVNTPELN
                     VFNGDMGEITGIILAKDSEDKVDELVIQFDANEVTYKRNEWNKITLSYCCSIHKSQGS
                     EFKMVILPMVHQYQRMLQRNLLYTAVTRSKELLILLGEEQAYVTCVANESASRMTTLK
                     SRIMDNDKMNITLRTKLAAYEDSLVGNDPFEDGNYTKEPRVVKEKLPVEDDSGTNETK
                     NQVMETVEPDLFSSFVGEEKKEEVEPAVSKDFVLTAEVIDNQLVDPMIGMENSSPYDF
                     IPAKNA"
     gene            complement(20738..21397)
                     /locus_tag="ACG8LA_001635"
     CDS             complement(20738..21397)
                     /locus_tag="ACG8LA_001635"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HFQ0203937.1"
                     /translation="MELYFTRHGKTQWNQERRFQGSNGDSPLLPQSYEEIKAFGKKVK
                     YVPFKAIYSSTAKRARDTAEGINKELARPVEIFYTDKLRELGLGTLEGQSIDEMYQKY
                     PDNLPNLRNHLDLYDPSPFHGETIESAITRIETVVADAVARHKDGPLLFVGHGASLTA
                     AIQWMTGKELSELREMGGLFNSSLTILETEEPCRLLPYELKVWNQTDFLGTETAPEPL
                     L"
     gene            complement(21446..21949)
                     /gene="trmL"
                     /locus_tag="ACG8LA_001636"
     CDS             complement(21446..21949)
                     /gene="trmL"
                     /locus_tag="ACG8LA_001636"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008175 - tRNA methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HFQ0203938.1"
                     /translation="MNHIVLFEPLIPANTGNIARTCAATNTPLHLIEPLGFSTDDKHL
                     KRAGLDYWNDVNITYHSNLEAFLTFLGNRKLHLISKFAHKVYSDENFADGEEHFFLFG
                     KETTGLPETFMRENEEKCLRIPMNDEHVRSLNLSNTAAMIVYEALRQQGFPNLELTHH
                     YENDKLD"
     gene            complement(22170..23036)
                     /locus_tag="ACG8LA_001637"
     CDS             complement(22170..23036)
                     /locus_tag="ACG8LA_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HFQ0203939.1"
                     /translation="MLKKIDRGRQFLAENHQLFRCPVCQEEVKKSDNGLICKNNHRFD
                     LSKKGTLYFLSHAVKTEYDQGMFVPRRRMIQSGMYQPVIETIAQHLPEEVSLLDVGCG
                     EGSFLNELSKLKKIQNAVGFDISKEGVYAATEQSAEAFWCVADLTNLPFADQTFNAVL
                     NIFSPSHYQEFQRVLSEDGEVLKVVPQENYLKELRQAFYPNQPEKQSYSNERVVAKFA
                     EAMKLTERQRVTYEFEIPEENQKDLLAMSPLEWQVEERIKADLYKNPLKKITIDIELL
                     KGTKRKRFSSSF"
     gene            23145..23786
                     /locus_tag="ACG8LA_001638"
     CDS             23145..23786
                     /locus_tag="ACG8LA_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005507 - copper ion binding [Evidence
                     IEA];
                     GO_process: GO:0055070 - copper ion homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HFQ0203940.1"
                     /translation="MIKEFCAENYTSIPLAIARGADRIELCDNLAVGGTTPSTGVIEE
                     TLSYAGEKDIPVMTIIRPRGGDFVYNDIELKIMHTDLIEAKKLGTDGVVFGCLTPSGW
                     LDEEALELLIETAEGLQITFHMAFDSIPEDRQFEAIDWLVEHGVDRILTHGGPADKTI
                     VENFPRLKELIAYTDGRLIILPGGGVTAENAAHVAKELNVSEVHGTKIVDLQL"
     gene            complement(23848..25209)
                     /gene="mgtE"
                     /locus_tag="ACG8LA_001639"
     CDS             complement(23848..25209)
                     /gene="mgtE"
                     /locus_tag="ACG8LA_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015095 - magnesium ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015693 - magnesium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HFQ0203941.1"
                     /translation="MDENQELEERFAQLTQDLRENNIQAFRNSFLEMHIYEQGQFYQS
                     LTEENRQLIYSYLSPKELADMFDVIEEDNEHMKEYLDEMRPSYAADMLSEMYTDNAVD
                     LLNTLDKKQIAKYLSLMSADDASEIKELLHYEDETAGAIMTTEFVSIVANQTVRSAMY
                     VLKNEADVAETIYYIYVVNQEGQLVGVISLRDLIVNDDDAMISDLMSERVLSVHVGDD
                     QEDVAQTFRDYDFLALPVTDYDDHLLGIVTVDDIIDVIDDEAASDYSGLAGVNVEEIN
                     ENPVKAASRRLPWLITLLFLGMSTASLISHYEDLVSEASILAVFISLITGTAGNAGTQ
                     SLAVAVRRLAISDEKDHGFVRLVLAEVLTGVVTGAVTGITIFLIVGFWKHNFILGFVI
                     GMAMLFAITVANLAGSLIPMLMDRLGFDPAVASGPFITTLSDLTSVLIYFNIASLFMG
                     YFM"
     gene            complement(25227..26126)
                     /locus_tag="ACG8LA_001640"
     CDS             complement(25227..26126)
                     /locus_tag="ACG8LA_001640"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HFQ0203942.1"
                     /translation="MQFTWDYEKDHSQQVKYFLKEKGISKGLLAKIKFQGGQIKVNDQ
                     VENVLFSLAKDDKVTIVIPAEGEHETVLLDETPIDIVYEDEHVLVVNKPAGVSSIPAQ
                     YHPNGTMANRVKAYYKKQGYENQVIHVVTRLDRDTSGLMLFAKHGFAHAKLDMQLREK
                     KFVKKYQALVSGRLSDLSAHGHIDLPIARDYSSLLKRMVSDEGRSAQTEYWIEKRLTE
                     IALVDIQLHTGRTHQIRVHFSAIGCALLGDDMYGGRMDLGIKRQALHCYDLRFYHPFT
                     EELLEFKQPLAADMEAVVRRFEE"
     gene            complement(26128..26925)
                     /locus_tag="ACG8LA_001641"
     CDS             complement(26128..26925)
                     /locus_tag="ACG8LA_001641"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003951 - NAD+ kinase activity [Evidence
                     IEA];
                     GO_process: GO:0006741 - NADP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HFQ0203943.1"
                     /translation="MKVAIVHNKEAKTIEVTERLNALLEQAGIQRDDHEPELVISVGG
                     DGTLLSAFHHYSHCLNDVRFLGVHTGHLGFYTDWRDYELEELVDSLRTNREQSVSYPL
                     LDVRISYLDETPDQHFLALNESTIKRANRTMVADVYIKNELFESFRGDGLTISTPTGS
                     TAYNKSVGGAVIHPSINAFQLAEIASLNNRVFRTLGSPIVIAHDEWLEIKLENTEDYL
                     VTVDQLNVAKANIRSIYYRIAEERIHFASYRHMHFWHRVKDAFISED"
     gene            complement(26903..27607)
                     /locus_tag="ACG8LA_001642"
     CDS             complement(26903..27607)
                     /locus_tag="ACG8LA_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015969 - guanosine tetraphosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HFQ0203944.1"
                     /translation="MERDWEAFLAPYEQTVSELKVKLRGIRKQFREQNRHVPIEFVTG
                     RVKPVDSIVTKSQLRHIPMGRLEEEMSDIAGLRIMCQFVEDIHQVVEIIRKRKDMKVL
                     QERDYITNKKASGYRSYHLVIEYPVQLISGEKKILAEIQIRTLAMNFWATIEHSLNYK
                     YQGVFPEEMSERLQRAAEAAYQLDEEMSSIREEIQEAQRLFSHGRGKSDDVYYRTLLK
                     KESEREEAGDESSDRS"
     gene            27738..28313
                     /locus_tag="ACG8LA_001643"
     CDS             27738..28313
                     /locus_tag="ACG8LA_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HFQ0203945.1"
                     /translation="MTQMLEIEYKSMLTKQEYEIFIAHYQLTDKDFRVQTNIYFDTVD
                     EQLKKQNCGLRIRFVGHQAEYTLKTPAEKGRLETTDTFITEEAEAFIFEKRLPRSGAV
                     FQKLSDLNIDPASLIQTGKLTTKRAEFPIEEGLLAIDESWGDNLHDFELELEVGDASV
                     GKIAFINFLKRFSLPYRPAKNKIQRMLEAKN"
     gene            28431..29108
                     /locus_tag="ACG8LA_001644"
     CDS             28431..29108
                     /locus_tag="ACG8LA_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClpXP adapter SpxH family protein"
                     /protein_id="HFQ0203946.1"
                     /translation="MIEIYLFVNPLGEYCFEMEQQLLQFIEEEYGTPSKEKMQFRFLP
                     LVNLQTIGDVMQQKGISQNNLEERNHLFSMTYSAALDCKAAQFQGKKKGRRFLIKLQE
                     AVGCNDIPYSQELAESIFEEIGGDLNMFKEDRQSDFVKEVFFSDQKIAREMGITKHPS
                     AVVYNYACDRDFGVLVEVKGTSSLWRITELCKTTDNSYQVFNGEHLHTNDSQFHSRTS
                     HLHLLSN"
BASE COUNT         8566 a         6169 c         5232 g         9143 t
ORIGIN      
        1 aatacagtat tatttcggtt gcttgctgct tcacctagcc cttgtactcg tgtttgattg
       61 gcgacttgac caaattgatt cccgacgtct aataaaataa tagctaaaag caaaatggcc
      121 aaatggcttc cgccaaccaa taaagcaata aagcttattg tttgcataac aagtcccata
      181 tacacgattt ttctttcaga ataagaatct gccagtcgtc ccacgatagg tgcagcaact
      241 gctccagaca aaccaaaaat cgctaatatc cctgcttcga atgttcccca attgtaggcg
      301 ggactgctga tataaaaaat caacgtagac caaaagatcg aaaatgttcc aaacatgaaa
      361 aatccactga ctgccgcttc tcttaataga cgttgagaag caactaaatg cggcaaactt
      421 ttaagtgaat caaggtatga aacagctgta ctactttgct ggacagaacg cggcattttc
      481 cagtaaagca gaagtgtaag aattccgact gcacataaag caaataaata gatcatccgc
      541 caagaaaaaa gactggcaac aataccagat accgtccgag aaagcaaaat ccccacgagt
      601 aaaccgctaa gcaatgtacc catgaccttc cctcttgctt ttggtcccgc tagtaccgca
      661 ccgtaaggaa tgatgatttg cggcacgatc gaaagtaatc ctattaaaaa agaagcgcat
      721 gcaaataacg taaacgaagg cgcaaaaaaa gcggccaaca gagagacggc agataacgct
      781 accattcgaa tgatcaattt tggacgatcc accacgtccc ctaaaggaac taaaaacagt
      841 aaccctaacg catagcctaa ttgggtcaac atcgtcaata tcccgactgc acttgtgcta
      901 acagataaac tagctgctac ttttgttcca atcggctgga tgtaatacat attggcaaca
      961 acaacgccac aagtgattga taatagtaaa ataagcgaag ttgttaaagg tgttttttca
     1021 ttactcttca ttgatttccc ccatttccta tcttagttta caacttatgg aaaagattgg
     1081 aaatagaaaa atacaactat tcgccacact tattatttgt gcttttgttt tccttgtttt
     1141 ttcttgcgat ctttataaat gaagacaact aaccctacta gcacagtaac acttgcaacc
     1201 aacgtgactg cagttttgtt atatccgtga aacagagctt ctccaccaca cgcatacaac
     1261 acagacgaag ggatgactcc aatcacgatc gacaatatga tttgctgtag aggcaatttc
     1321 atcgcatctg cagcaaaatt gaccatagaa gatggaataa ccggtatcat atagcctaac
     1381 attacaccta tttttggatg tttcatttgt cggattgctt gcacccaatg attcgtttcg
     1441 gttttcttat ctaaaaattt taagcgatgc ataaggaaaa ttgcagtgat gttaccaaga
     1501 gcattaccca aaatgttgat gatcgcacct gtcagtggtc caaagctcaa accagcaatg
     1561 actccaacta ctgaagtagg aatacctgga acagcacaca tcaccgctgt caatacgatc
     1621 aagagtatcg atgcaaaagt cccatgcgaa cgaatatgtg cgagtagctc tgccttactc
     1681 gctctcggat ttaaaaataa ttggatgtct gtctgatatt ctaaatacaa ccgatagccc
     1741 actaccagta tcagaatgat tcccaacgag atcaacatca atcggattat tttctttttc
     1801 atatttcctc ctgaaaaaaa tctatattca ttaaataata gtttaacata aaaacaaaaa
     1861 agcaccgaaa tccaacatag gatctcagtg cttttaaata gtaaaaatta tttaacagtt
     1921 acagatgcgc caacttcttc aagtttagct ttcaattctt cagcttcttc tttagatacg
     1981 ccttctttaa ctggtgcagg agcgccatca actacagctt tagcttcttt caagcctaaa
     2041 ccagttgctt cacgaactgc tttgataact ttaacttttt ggtctccagc tgcagttaat
     2101 tctacagtga attctgtttg ttcttcagca gcagcagcgc caccagcagc agctacagct
     2161 acaggagcag cagcagatac gccaaattct tcttcaatag ctttaactag gtcgttaagt
     2221 tctaggatag ttgcttcttt taactcagca acgatgtttt caatgttcaa tgccattata
     2281 atttcctccg tttaattgtt cttttttatt taatgcttta tgcggcaatt aagctgcatc
     2341 tccatcttct ttgtctgcca ctgctttgac agcgtaagcc acgttgcgga ctggcgcttg
     2401 tagtacagat agcaacatag atagaagtcc ttcgcgattt ggcaattttg ccaatgctgt
     2461 gatttcttcc aatgaagaga ctttaccttc gatgataccg cctttgattt ctaatgcttt
     2521 tgcttcttta gcaaattcgt ccatgatttt cgctggtgcg actacatctt cgttactgaa
     2581 tgcaacagct gtaggtccag tgaatacttc gtccatgcct tcaaggccag cttttttagc
     2641 tgcacgtgaa agaatagaat ttttgataac tttcatttct acgttagcat cacgaagttg
     2701 tttacgtaaa cgtgttactt catcaactgt taatccgcgg tagtcaacga ctactactga
     2761 tgcagctgct gtaaattttt cgcttacttc atcaacgatt gctgcttttt ttgcgataat
     2821 tgcttcactc atttttgagt ttcacctcct gaattttgat ggaagagttt tttgcactga
     2881 aaaggcaagt cacttttata gttactttgc tcaaccagta ttattcatca cctattcact
     2941 tcgttcatag tgattctact cgctttgctc gaaaggaaac tcctttcgct ttgctcaacc
     3001 agtattgttc atcatctctt cacttcgttc atagtgattc acaataaaaa actctatgcc
     3061 accgcagaca tagagggact attgaatata ttcaataaac gtcctcggta ggaaattaag
     3121 gcttgatgcc acctactgtc ttcggtacaa gttaattatt aacctcaact agcttagcat
     3181 gctaaactag ttgagtcaag aattattttt cagttggatc aatcaacatt ctaatattta
     3241 attagaaaga agcttggtca acatggatac caggtccaaa tgttgttgtg atcgttacat
     3301 ttttcatgta ttgaccttta gctgctgatg gtttagcttt tagcaataca tcatggattg
     3361 ctgcaaagtt ttcaactaat ttttcatcgt caaatgaaac ttttccgatt ggtacatgga
     3421 tatttccagc tttgtccaca cggtaagtta ctttaccagc tttcacttcg tttactgctt
     3481 ttgttacgtc cattgtaact gtaccagttt tagggtttgg cattaagcct tttggtccta
     3541 atactcgtcc tagacgacct acagtagcca tcatatcagg tgttgcaaca actacatcaa
     3601 agtcaaacca tccgttttgg attttttgaa ccatgtcgtc gtcacctacg aaatctgcac
     3661 cagctgcttc agcttctttt gctttgtctc ctttagcaaa aactaaaaca gtttgtgttt
     3721 taccagttcc gtttggtaat acaacagcac cacggatttg ttggtctgct tttttagggt
     3781 ctacgttcaa acggtatgca acttcaactg ttgcatcaaa ttttgcaatg tttgtttctt
     3841 ttgctaaagc tactgcttcg gcaacaggat aaactttact tgaatcaact ttttttaatg
     3901 catcttgcat ttttttgctc tttttagcca ttttggttcc tccttgattg tggttataac
     3961 ggttgtacct cccacgtgtt ctatatcttt caatatagag ccaactgaga agctgctgtc
     4021 ttagggtgta tagattattc tacagtgatc cccatgcttc gtgcagttcc ttcaaccatg
     4081 cgcattgctg cttcaacgtt agctgcgttt aggtcttcca tttttaattc agcgatttct
     4141 cttacttgat cgctagaaac tttcgcaact ttatttttgt ttggttcgcc tgaacctttt
     4201 tcgattttag ctgctttttt caatagaaca gcagctggcg gtgtttttgt aacgaatgtg
     4261 aatgaacggt cttcgtatac agaaataaca accggaatga tcaaacctgc ttgatcagct
     4321 gtacgagcgt tgaattcttt tgtgaatccc atgatattga tacccgcttg acctagtgca
     4381 ggacctactg gtggagctgg agttgcttta cctgcaggaa tttgcaattt aacgattttt
     4441 tctactttct ttgccacgag acatacctcc ttaagtccgt gatgtggtta attggagatg
     4501 catatttctc ctcccacgtt ttatctgatc tgaaaaaatc cagacaaata atgtgcaaaa
     4561 caatgcacac tggtacagta tagcaaattt atttgttttt tcaagatttt tttctgctat
     4621 ttttacattt tgcttgaata aacgctaaat ttattctaaa aaaacaacaa tttttcgttc
     4681 tcatttcttc ttttatgtta cacttgcgct agcatggttc aacagatgaa agcaaacaat
     4741 aacacggttt tttagaccct tgtacaaaga ttcctacata acaaaatgag gtggagaaaa
     4801 tgaaagattt aaggtataga agtgtctttg atattattgg acctgtgatg attggtccaa
     4861 gtagctctca cactgccgga gctgctagaa tcgggaaaat catacgtagt atatttggcg
     4921 aacagcctga ttctgtagat atttatctat atgaatcatt tgcaaaaacc tatcgggggc
     4981 acggaacaga tattgcatta gttggcggcc tgttagggat ggaacccgat gatgaacgtt
     5041 tagctgattc tttgaaattg gcatatgaag ccggtatgga agtcttgttt gttcctaaga
     5101 gtgaaaaagc cgaacatcca aactctgtaa agatgcttct aaaaaaagga acacgaaagc
     5161 tttcagtcac tggcatttcg atcggcggtg gcaatatcca gatttctgaa ttgaatggat
     5221 tcaaaatttc tttaagcatg ggtactccta ccttgatcgt tgtccaccaa gatgttccag
     5281 gtatgattgc taaagtgact agtatacttt ctgagaccaa tacgaatatc ggcactatga
     5341 cagtgacacg ggaatcaaaa ggtgaaaatg ccattatgat aattgaagta gatgatcctc
     5401 aagtagaaga aacggtaaaa agactcaaac agctgccaaa tatcgacagc gtaaattatt
     5461 tcgattaagg agctaaaaaa atgtttttat cgattgaaga attagtagat caagcaaaag
     5521 cttatccaag tgtagcagaa ttgatgattg cagttgaaat ggaaatgagt ggccgttccc
     5581 gtagtcacat catcgagatc atggaaaaaa acctctcagt aatggaacaa tcaatcaacg
     5641 agggaaaaga aggtgttacc tccgtcacag gaattaccgg tggtgatgca aaaaaattag
     5701 atgattattt aaatgaggca gactttttaa gtggagaaac aatcttaaaa gctgtacgca
     5761 atgctgtagc tgttaatgaa gtcaatgcaa aaatggggtt gatttgtgct acaccgactg
     5821 ccggaagcgc gggtgttgtt cctggtgtgc tgatggctgt ccgagatcgg cttgatttga
     5881 cacatgaaca gcaattggaa ttcttattta ccgctggcgc tttcgggtta gtcatcgcaa
     5941 acaacgcttc tatcagtggt gcagaagggg gatgtcaagc agaagttggt tctgcaagtg
     6001 caatggcagc agcagctttg gtttgtgcaa aaaatgggac tcctcatcaa gcagcacaag
     6061 cagtagccat tacattgaaa aatatgatgg gactgatttg cgatcccgtt gcaggcttag
     6121 ttgaagtccc gtgtgtcaaa cgtaatgctt taggctcttc tcaagctttt atctctgctg
     6181 atatggcatt agcgggtatc gaaagtgtca ttccgccgga tgaagtcgtt gctgcaatgt
     6241 accaagtcgg acgtcaaatg ccgtcgattt tcaaagaaac agcagaaggt ggcttagctg
     6301 ttacgccaac tgctaaacga cttgcggaag agattttaaa taagagggcg tgataaagct
     6361 ccttaatttc gagtattaag agattagtta tcttcataac aaaaaacgaa gagaggacta
     6421 attgcccttc tcttcgtttt ttattaatcc atcaatttcg tattttttac ttcatcgatc
     6481 gtttttgttc ctgcaagttg catcgtgatc gacaattctt tgttcaggtg ttcaaaaaca
     6541 gatgttactc cttctgcccc acctagattc aacccataaa tcactggtcg gccaatcgca
     6601 actaagtcag caccacttgc cagagctttg aagacatgct ctcctcgacg gacaccagag
     6661 tcgaaaatca ctggtacacg tttgttgact acttcggcaa tttttggcaa tacttcaaag
     6721 gacgcaggac ctccatctaa ttgacgtcca ccatgattgg atacccagat accatctgcc
     6781 cctgcagaga tagcgattac tgcatcttct ggcgattgta ttccttttac gataactgga
     6841 agatgggtga tttctttgat tgttttgatg tcatctggtg tcaagccttg ttttgcagct
     6901 gcataaattt ctgcgattcc ttttccttcg ccattaccac ttgcactttg ttcgctatac
     6961 gcagctaagt taggcattgg taatggaaat tggaattgat tgatgacgtc ttcttcacgg
     7021 taaccaccga gcgttgaatc tgccgttaaa atgatagctt tagcccctgc ttctactgct
     7081 ttgttcaaaa tgaactcatt gaatctgtcg tctttactca tatataattg gaaaaactgc
     7141 ggtgcgcctg gcgctgcatc ggctgcgtct ttgattgtcg tatttgcata agtgctgatg
     7201 gaaaagattg atccagcagc agctactcct ttagctgtat cagcttcccc tttttcatgt
     7261 gccaatcctt gggccgctga tggcgcttgg ataatcggtg tatctaattc aattccgaaa
     7321 acagatgtat gcaaatcggc tgagtcgatt ccgcgtaata tccgtggcat gattttcttt
     7381 gtattaaaag aagtcgtatt ttctttcatc gtccactcat cttcagaacc accgcgaata
     7441 tagccaaaag ctcctgcttc catgcgctct tttacacgac cttctagtta ggcaatgttt
     7501 acaatatcga ttggatgttc ttcattactt gtatgataag tcatagtaga tccttctttc
     7561 atcttcttga ttacatataa atcatactaa acttacaaaa agtaagcaaa catttactct
     7621 cagatacttt tatcgctatt ctttccaaat aaatcgactt acaagctgat ctacttcttg
     7681 gttttcatga agcatactat gagaggcatt ttcacctgtc actacttttt cctctatttc
     7741 atttccgcgt tgcttcaaca acgcatagac cgctaatgca ctgtttaacg gtactgttcc
     7801 atcactcaag tctgtttcat ctagttgacc agcaatcaag aaaaatcgag tggttatagg
     7861 aatattaccg atcatttgct ggtaatcttg atagcggtta gaaacgacag caggcccctt
     7921 tgctaactca tctgtcagag actgcgcact atcatcgaca aaatcattaa aaggcgcgcc
     7981 aattgctgtt aatgtctgaa cttgtggcaa tgacgtatcc tgtccatacg ttcctaaata
     8041 gcgtagtgca ctaactcctc ccatggaatg ccccactatg ttgactttat ctatgccgta
     8101 gttttctttc agatacaaaa gacaagtttt gatccattct gcttgattcc actcgttatt
     8161 tttattatct tcaaacaata cttggaccat cggattgtct gcttttccag acaaatctcc
     8221 tgttgcttgt atttgtccat ctgttcctac tgttaaaacc aattctttta ctgcttgctg
     8281 atttttttcc aaacgccgca acatcccttt aaaggaattt tctgtcccgc tgtagccgtg
     8341 gaaaaaaagt gttggaatag tggttttttc tatcacttta ctggattctg ccgttttttc
     8401 tttatcagaa acttcagtag tatttatctt cgtcgtctgg caaccactta acgcaaacaa
     8461 actgataagg actaaagctg ctgcagttgc acgtttgcat aaatttttga ttggttctgt
     8521 catacacctc ttcctttcca tatagaaaaa agaaagactt gaaaggccaa tcatatgatc
     8581 gacatttcaa gtctctttat taatcgattt tatctacttg atcgaaatca agttctgtac
     8641 tggtttcacg tccaaacata tcgatgttga ctttcaattt ttctttttct ccgtcaactt
     8701 ctgttacttg tccttctaat ccagcaaatg cgccttcgat gattttcacg acttcgccaa
     8761 cttctacttc tagatcattt tgtcgcaggc tcataccgat agaacgcaag atatgattga
     8821 cttcttctgg aagtaatggt gctggtttgc ttccggctcc gtgtgaacca acgaatcctg
     8881 tcacaccagg tgtgttgcgg acaacatacc atgaagcgtc tgtcatgatc atttcaacaa
     8941 gtacgtatcc tgggaatgtt ttatgaacga tttctttttc tttcccattt ttgacttcag
     9001 tttctttttc ttcaggaaca acgacacgga aaataaagtc ggccattttc atactttgcg
     9061 cacgagattc gatatttgct tttactttgt tttcatatcc tgaatatgta tgcaagacat
     9121 accagttttt ttcaaaagat tccattgaag gctcctcatt tcattgtaaa ataaaaaaac
     9181 ctcagtacac ccgaagtttt tctttcgctt cattatagca ctaaaagtac gttgtggcta
     9241 gcgagttatt ttaaaatcca gccaaataag ctttggatgg ctgtatccat tacgtaaaac
     9301 atcaatccga aaataataga agtttcgatg actactaacg tatctttacg gagttgtttt
     9361 ctgcttggcc aagttacttg tttgatttca tcttttacgc tttttagaaa tttcatgaga
     9421 caacctccct tgctactgtt tatttcgttt ctttatgtaa tgtatattga ttacaatatt
     9481 tacaaaactt attgatttcc aaacgttcgc cgctttttcc ttcactgact gattttgtgt
     9541 agttgcgaga cccacaaacg gaacaagcga gtgctgcttt tttctttgcc atttacttct
     9601 gcccccttgc tgagaatcag acttatactt cataacagta tcacgtaact ttttacttgt
     9661 caatttgtga aataaactat ctattgtttt ggataaaatt atgatatgat taatttgaaa
     9721 ttaagctaaa atgagacaat tggaggtata gcgatgctat taaaaacact tgtatataag
     9781 aaaaaagatc tgacaaccgt tacagagact agtacattag aagaagcatt aaaaatttta
     9841 gaaacttccg gataccgttg tgtgccgatc ttagattctt caggtaatat tttccgtgga
     9901 aacatttaca aaatgcatat ctatcgtcat aaagcaaatg gcggtgatat gacgcttcct
     9961 gtcactcatc ttttgaaaaa cgctacaaag ttcatttacc tggatacttc tttcttcaaa
    10021 gtattcttta cgatcaaaga gcttccttat attgctgtcc ttgacagtga aaatcatttt
    10081 tatggtattt tgacacatag tacgttgctt aatatgctct ctcaatcttg gagcgtagaa
    10141 caaggaagct atgtactgac aattgcttcc acaggaaagc aaggagattt ggctgctatt
    10201 gcaaaaatca tttcaaaaca cagcagcatt gccagctgta ttactcttga tatcgaaaaa
    10261 gacgaataca ttcgacgtac attgatcacg ctaccggcta acactgaagc gaaagtatgt
    10321 gaaacgatcg tcaaccactt agagaaaaag aattataaag tggtagaaat tgaaaatttg
    10381 caaaaccaag aagcataatc aaaaagcgaa aaaagaaaac agctaatctg ctttcttttt
    10441 tcgcttttta taattagaca cgcttttcaa aatcaagcgc gcgatctaaa taatacatca
    10501 atggtgctga aacagccatg acgataaact cacttaatgc aagcgtgcca taggttgtcc
    10561 aaaatgcttg gccacctgtt ggaactaaca tataagcaat cagtcccatg ctgatggtaa
    10621 agaagatcgt gttcaatact aaacgcatct ttacattttt cactttgttt tgcaataaag
    10681 ctgtcaggcc taaagaaagc aatgtttggc cgccaccaaa aaccacatcc atgataccaa
    10741 aaccaaagaa ggcattatag acgatgaccc cgcctaaaac tccccaaagc aatttacggt
    10801 taaagacaac taaatgattc aaactttctg aaatacgaaa ctggatcggc cctgaggata
    10861 caggcgcaac taaaatagtt aacgctagat aaagagccat gatgatgcca tttacaacga
    10921 ttacggataa ccgttgtctg cttttcgttt tttgcatttt ctctcctctt ttctcctagt
    10981 ttttttaacg cgggatggtt gatgaaccgc ggttatgtga aacaaacaat aattataaca
    11041 gacttttcat ttatttcaat ccgtcttatc tgcttttaaa aaagcaaaag cttaaacaat
    11101 gtaaacgttt gctaaaaatc gtgggatatg gtataaagta agtgtaaggg gtcataagaa
    11161 ttcccagtaa agcagacgaa gtaggatctg caagaacaga attgttgtga aacttaaata
    11221 aataaaaaag gatgtgggaa tttgagcaac ctcttactag agaacggtct agcaagcagc
    11281 tgaagatcta agtggacatg ccgaaccttg gaacttctcc ttacgtaagt aatggatcat
    11341 gcgcttgcta ggcttttttg tgtttttcgg tcttcggacc tttttcattt tcctagactt
    11401 ctgctataat aaccaagaat taattttgta acagattttt ttgaaaaaac aagtttcttt
    11461 cattcaaaaa atagaaaaag cttgctaatt attggttaac cagcaaacag gagtattaaa
    11521 atatcttgtt ttattgaata gcaggaggaa atcatgaaat tccattatca tatattgatc
    11581 aatccatcgg caggcagcgg aaatggctat aaagtagcag aaagaatttt accggtatta
    11641 aaaaataagc atattgacta tacacttcat tatagtgaat acaaaggaca cgatgctgag
    11701 attgctgaaa ctttggcaaa agaaacattg attccttgga tagaagaaga acagaaaaca
    11761 atcgatactt tccccctttt gatcatcgta ggaggtgacg gcaccttaca tcaggtactt
    11821 gatactttct atcagatgga agtagaattc ccagttgctt atattccagc aggttctgga
    11881 aatgattttg ctcgaggggc aggccttcca aaaaatccca aaaaaggact tcagctgatt
    11941 ttagcagctc aatcaccaga aaaagtccac ataatggctt atgaagaaaa aataagtgaa
    12001 aaaaaaggaa tagctgttaa taatttcggt ataggattag atgcagctat cgtccatgcg
    12061 acaaatcatt cttccacaaa aaagcgattg aacaaataca acttaggatc attttcgtat
    12121 ttattctcta ttctccgtgc tttattcact caaaaaggat ttccaattct ggtagatgca
    12181 ggaggaaaac aattaagttt ttcaaacgca tttttatgta cagcaacgaa gcatcctttt
    12241 tttggcggag gaatcgcgat tgttccaact gctgatgcgt ctaaaccagt cattgatttt
    12301 gtcgtggtcg aacgaatcaa tttctttaaa atcttgtggc tcattctttt acttatacag
    12361 aaaaaacaat tgaaatcgaa atatttccat cactacacaa caaacagatt acgtatcgtt
    12421 tcaacaacac cgcaacatgg tcaagaagat ggagaagaaa tggaaaaacg accttttgat
    12481 atcacaataa ccacaactaa acagttgttt tggtgttaat aaaagaggtt ttgtcagaag
    12541 ctacatctgg aacaccgttt attcggaaaa aaggactgtg acacgacttt tgtcacagtc
    12601 ctttttttac tatgcagtta attctttgcc caattgggtt gccatcgata gtttctttct
    12661 ttacccaaaa taaattggat cattgaaaac accgcagcaa aagcaactaa gacacaacca
    12721 ttgaaccaaa aagattctgc aaatgtttga ttgtaactga gtgtttcact gatcaagtta
    12781 ttattttgaa caaaccaata tgttggtgtg aatgccgcta ttttgctaac catttctggc
    12841 aagtattctg ctggtacaaa caccccaccg ataaagcaac tgcctgtgat aaaaatatct
    12901 ttgatcccac cgctggtttc tgagtttttt accaatgaag tgatacaagc cgaaaagcta
    12961 atgatcggca ataaaaacaa gaaagtattt aaaatatgat accataccgt tatatcccac
    13021 gaggtgtgga tcactaacag aaccattaga agtaagaagc cactgaacaa cagcagcgag
    13081 taactaatca aactaaaggt tactttgcga ttcaagtttc gtttggtaat gggcgcactc
    13141 tggtttcgtt tactgatctc tttgcgatta aacgctagat tgatgacgct gaaaccgcta
    13201 aaaatggata gaaacaaccc ataagacaag aaattaaagg ttgtgcccgt caacagcttt
    13261 ttcatccgct gactatatcc cgcacttagc tcaacttctc cagtaaccga gagtgccatt
    13321 tgtgtctgtt ccatagctgc atcgattgtt ttatcttctt cttgaaacag aatcagtgtt
    13381 tgcaaaaagg tgttcacttg ctgtgtaaca actgttttag aaaaggcatc tgggcgactc
    13441 tgtatcttga tcgtcgccat ctttcctact tcgacttgtt cggtaaagtc tgcaggcaga
    13501 tgtaagataa tgtttacacg attaaaataa agagcatcat cgatttcttt ttgtgaggtt
    13561 ccatccaatg taacgactgt ttccttgtca ttcaaatatt tacgaaggcc atcgactaca
    13621 ggcgactctt cttcactaat caaggcgatt ttcgcatctt gcagagaggt attttcaaca
    13681 tcaatatttt gcgcaaaaaa gaatgtggca acaacagtga taattacacc tatcagtaaa
    13741 ttcgatttat ttgctttaag caatgtccaa atcgttttat aaagcgtcat aacgcacccc
    13801 tctttccatc caagcatttc ctaacgcaaa aaggaaaata aatccgatca accatagaag
    13861 attggtataa aaactagcca aatcagtgta gaaataaagt ttatacaaac tttcgctgat
    13921 caagttgacg agatttaatt gaccaacaat cggaatatga agatcaatcc aatacttcac
    13981 ttgttccgac cccatcatac cagcaaaaaa gctcatcgca atcgtcactg aaatcaagat
    14041 gctatccttt tgcaccagat tcatttttgg tatcaaatta ccaaccaatg tacctaacaa
    14101 aatcgcacac aacgacccca gagcggtaac aatcatcaac cattgccaac gttcaccaaa
    14161 gtctacttga tagataaaac gaaagacagc taacataata taaatctctg tcaaaacaat
    14221 cgtaaagctt gctgccaaat tagcgattga aactaacgat tgctttctag gaatcaagga
    14281 caagcgaata ccatttgacg attgatttgc ttgctgatcc tgtacattgc ggacccccca
    14341 catcgtcccg tagagaatcg ccattccaat cagagtgaag aaataaaaac ttttgaaact
    14401 catattacga cctgcatgaa cttcttgaaa agatacttct tgttcaaaaa cagtcatgat
    14461 gggcgcgaga tcaacgttct ccacttctgc cactttactc gaaattatac caatacgctg
    14521 taaaaattga tccatgacgt ttttcatcaa cgtctgactc attcctgctt gacccacatg
    14581 gagcgaaaca gatgaaccat caatgagata aaaaccagcc aaatcatctg catttagctt
    14641 ttcattcgct tctacttccg atagttcctg tacttcaaat aatggtttat cattgacttc
    14701 gacttgttct aagactgtgg taaaattttc cgaaagcgct gtttgatccg ctttgattac
    14761 aattccagta ttaatcgttt caagattgcc accttgatca atctcgccaa aggccgccat
    14821 aaacatcaat cctaaaagaa ttggaaaggc caatgtccaa aacaacatgg atttatttcg
    14881 cagcagtatt tttgtgcgat atttataaaa atgccaaaac attatttccc ctcctctagt
    14941 ctctcaaatc cttgccagta atctctaaaa agacatcatt caaggacgct tctttggttg
    15001 ctatttttcc gtaactgatc ttttcttctt gtaagattgt aagaatcggc aacaatactg
    15061 tatttagttc agtagttgtt acttggagct gacctttttt ataagcgatt ccatcagaag
    15121 ctattgttcg ctgaatcgct gacaacacat tttctgggag taatgggatg tcgatcgtca
    15181 aacgatccgc cgtccgtacc atatctttta gagattcttt ggttccttta gcaatcacct
    15241 gtccttgatc catgatcacg atctggtcgc aaagaatttc tacttcttcc atgtaatgtg
    15301 ttgtatagac aatggttgct ccttgtcgat tcagctcctt gatactttct aaaattttat
    15361 tccgactttg ggggtctaca gctactgtcg gctcatctaa aaaaattaac cgcggcttgt
    15421 gggcaatccc acatgcgatg ttcaaccgac gtttcaagcc accactaagt tctcctggac
    15481 gaaacgaaac atatttttct aatcccacta attgaatcac ctcttcaatc aaggctttcc
    15541 ttttctcttt ttcggaaaca tataaaccgc aaaaataatc gatattttct tgcacactta
    15601 gttcgtcaaa gaccgcaacg tcttgaggaa cgaccccaat cattgccttg acagcataat
    15661 tttcaggagt cattgttgtc ccgaacaatt taatggttcc tttgtcataa tttaacaaag
    15721 aaagcataca gttgatggca gtcgatttcc cactgccgtt tggacctaac agacctaaga
    15781 cttctccttc ttgtacttgc agatcaaaat gattcaatgc tacaaaatct ccatagcgtt
    15841 tgactaattt atcaatttcg ataatcatca tgaaaaactc cttccaaatt tcttgttgat
    15901 ctgactataa taaagtgcaa gaaaagaaac tagtgacgat tggctaaacc acacatgaca
    15961 tttgtcacaa tgaaggagtc tgctatgcat aaatctcggc tactcaacga aactagcttt
    16021 ctactggtta tctcattgct tttgctggta agtcaaggat tcgttgctat gcaagttatc
    16081 tatttattga tcgccgtttt attcactggt gtcagttatt tactgcctac aaagccaaat
    16141 tggattttcc aagttattct atttctttta tgtgcctttt tacctgatct tgtcctgttt
    16201 ctgccagcga cgatgcgagt gatcgcccct gaagaaagcc accttgatta cttgtttttg
    16261 ttaggttttt tgttgatttc gacggttggt aatcatcccc ccatcaaggt cgcctttgtc
    16321 gtaattttgc tgtttttttc cttttactta cgaaaaaaag atcaacgaac gaccgatctt
    16381 gagaaaaagt acattgtctc caaagatact cattgggaaa aacaacaaga gttatcggaa
    16441 caaaataaag cattggccct gtcacaagaa acacaattag ccttgcaaat tgtggaagaa
    16501 cggaaccgaa ttgcccgaga catccatgac aatgtcggtc atctgctgtc aagtgcgatt
    16561 ttacaaattg gtgcgcttga aatgatcaat caagaaccaa aactaaaaga accattagaa
    16621 aatttaagtg ccaccgttca cactgggatg gatcggattc gtcaaagtgt ccatgacctc
    16681 catgagacat cgatctcttt tcaacactcc ttagagtttc tgatcgctga ttttccttct
    16741 tctgttacga ttgaaggaaa cttgtttgaa ggattgaatg aaacgcagca aaactgcttc
    16801 ttaatggtca tcaaagaagc cttaaccaac agtatcaaac atagtcatgc caaaaccgtt
    16861 gttttacatt ttcgaacgtt gccggccttt tatcgcttgc aaatcacgaa tgatggcacc
    16921 agcccacaaa aaaattctgc tcccggtatt ggtttgaaaa cgatgcgtca acgtgttcaa
    16981 gaacaaaagg gacaagtcca tattttccaa gaaaaccagc aatttcagtt aacgatcatt
    17041 ttaccaaggg agggacacca atgataacag tagtcattat tgatgatgat ccatttgtga
    17101 cgaaatcgtt acaaaccatt ttagaaagca cgaaagagat ccgtgtgtta ggcattggtc
    17161 attgtgccaa ggatgcgcta gtcttatacg aaacccatcg tcccgatgtt ttgctgacgg
    17221 acatccgcat gcctaaacaa acgggcatcg atgctgccaa agaaattttg gctaaatttc
    17281 ccaaagccat ccttttgctt ttgacgacat tcaaagatga agaatacatc cgcgaagcat
    17341 tttccatcgg tgtcaaaggg tatttaatca aacagaactt gcaagcgatt attccttctg
    17401 tcaaatccgc ttataatgga caggccgtat ttggtaatga aatcatcgag actttcactc
    17461 aaatgatgaa gaataaaccg acgattgata gtcatgctta tgcttctttt agtgaacgtg
    17521 agcttgcaat catcaaagaa gtagctgccg ggaaaaacaa taaagaaatt gcagatgcct
    17581 tgtacttgag tgacggcact gttcgcaatt acatcagcca attactagaa aagctagatt
    17641 tacgggatcg cacgcaattg gctatctatt tttatcagca tttgcaataa gtcttatcta
    17701 acacaaaaaa acctgaatga tgctccttcg catcattcag gtttttttca catcttctat
    17761 tcaattgtcc cgcaaaccat ttcctcacga ttgaaagaat caaggattcg cagggctgcc
    17821 aggattcgtt ggattgttcg gcgtgttagg cggaaaaata ggcgccttgt ctaacgtttt
    17881 ttctagtttt gattcttcac gatcgtctcg ttctacatca ggactttcat tcaatttgaa
    17941 ttctttttcc atctcatcta actttttaaa gtcattgcca gattcttttg ctaatttcgc
    18001 taatttatct tcggtttctt tagccataaa gtaacgcccc ccttttgatt tcagcttagc
    18061 atatcacact gaaaaaacaa aagaaaacgc taaccaacga tcatttttag ctatttctca
    18121 tctttaaaat caagcatttt ttgccggtat aaaatcgtag ggagaactgt tttccatacc
    18181 aatcatcgga tctactaact ggttatcgat cacttctgct gtaagaacga aatctttaga
    18241 aacagcaggt tctacctctt ctttcttttc ttctccaaca aatgaagaaa acagatctgg
    18301 ttccactgtt tccattactt ggtttttcgt ttcattcgtc ccactgtcat cttctacagg
    18361 tagcttttct tttacaaccc gtggctcttt tgtatagttc ccatcttcaa atggatcatt
    18421 tccgaccaaa gaatcttcat aagctgctag tttggtccgg agagtgatat tcattttatc
    18481 attatccatg atccttgatt tcaacgtagt catccggctt gctgattcat tcgctacaca
    18541 agtgacatag gcttgctctt cccctaacaa aatcaacagt tccttactgc gagtcactgc
    18601 cgtgtagagc aaattacgct gaagcatccg ctgatattga tggaccatgg gcaaaataac
    18661 catcttgaat tcactgcctt gtgatttatg gattgagcaa caataagaaa gagtgatttt
    18721 attccattcg tttcttttat aagtgacctc atttgcatca aactggataa ctaattcatc
    18781 cactttatct tcagaatctt ttgccaagat gatacccgtg atttctccca tatctccatt
    18841 gaatacattc aattcgggag tattgactaa ttggaggact ttgtctccta tccgataaac
    18901 ggtgtcgttc caatgtactt ccttttttcc aggtttccct ggattgaata tctcctgcat
    18961 cattttattt aacgcatcga tccctgcagg tccccgatac attggtgcta atacttggat
    19021 atcttgtgca cggaatccct tatttttcgc tttttccaca attttagaga tcaagggttc
    19081 aatttgataa gcatcacttc ggaaatagga acgatctttt tgattctttg tgaaatcttt
    19141 tggcagacgt ccttctttga tctcatgggc aagaggaata atactagaac catcaccttg
    19201 ccgataaatc tgattgagtt ccattttggg aatttgttcg atttccaaaa gatcatggag
    19261 tacttgacca ggaccgacag agggaagctg atctttgtct cctactaaga taacttgcat
    19321 attcgtcgga atcgctttga ataatgtgtt agccagccat gtatcgacca tagacatctc
    19381 atcaacaatc aaaagtccgc cttctaattc tttcgtactg actgaaggtg ttttttcccg
    19441 tccattcagc cccagaagac gatggatcgt actggcaggc agacctgtcg tttcgttcat
    19501 tcgtttagct gctcggccag ttggtgctgc aagtagaata ggaaaaattt cttgggtata
    19561 ttttgaagga tccaattcca gtccgttcaa ctctgcaaaa agattgacga ttccgttgat
    19621 cacagtagtt ttccccgtac ctggtcctcc tgttaaaata aatagagggg aacggattgc
    19681 ttcagcgata gcttgttctt gcgaaggtcc atactgtatg ccgaatattt tttcgatacg
    19741 ccgaatattc ttctgcactt ctttttcagg ataatggatt tcttttttac gactgagaag
    19801 gcgctggatc gaattaccga tcccccattc agaaaagtac aaactgtttt cgtaaagatt
    19861 agtctcttct tgttgtatct ttccttcttc aacaagttgg ataattacag tagcaacctg
    19921 atcaggctgg atttcaattg ggcgacttgt ttctaaaata cggatcgttt gctgaagcaa
    19981 tgtctccgcc ggtacgtatg tatctcctgt ttgaactgca tgctgaaaaa tctgatgcaa
    20041 gatagctgct cgaattcttc tcggtgaatc tgctgcaata ccgatttgtt cggctagatt
    20101 atctgcacgt ttgaacccga ttccttctat gtcttcgact agctggtacg gattttcttc
    20161 gatgatatcc aaagactcgt tcttataggc ctggtagata ctgaaagcta actgactacc
    20221 gaacccgtaa cgattcagtc ccatgatcac ttgatccatc ccgtggttta gccgaatcgt
    20281 ctcagcaagc atttctcttt ttggcttcgt caaaccggag atttgtttta ataccgaagg
    20341 atcagcaatg attttttcga tagcatcttc tcccagcaat tctacaattt tttctgctgt
    20401 tttcttcccg attcctggga atttttcgct ggaaagatac gctacgatcc catttgcagt
    20461 tgttggcttt tcttgctcat atctttcgag tttaagctgc cttccgtatt taggatgatc
    20521 cactaattct ccataaaaac gataagtctc attttcttga atatcgccga aacttccggt
    20581 gactacaatc tctttttcac ggtaatcagc tgtggtttca ctgatgtgta ccaaaagcac
    20641 tttgtaaaaa ttactaggat tttgaaaaaa aatcgcggca actgtaccaa cgaaataagg
    20701 catttcttct ggctgcatcg gaagccgcct ccttcttcta tagtaaaggt tctggtgctg
    20761 tttcagttcc taaaaaatct gtttggttcc atactttcag ttcatatggc aataatctgc
    20821 aaggctcttc agtctctaaa atcgtcaaac tactattgaa caatccaccc atttcacgca
    20881 actcacttag ctcttttcct gtcatccatt gaatggctgc agttaaagaa gctccatgtc
    20941 ctacgaataa aagtgggcca tctttatgtc gggcaaccgc atctgctaca acagtttcga
    21001 tacgtgtgat tgccgattca atcgtttctc cgtgaaaagg agaaggatca tacagatcta
    21061 aatgattacg caaattcggc agattatccg gatatttctg gtacatttca tcgatcgact
    21121 gaccttctaa agtacccagc cctagttctc ttagcttatc tgtataaaaa atctctaccg
    21181 gacgagcaag ctctttgttg ataccttctg ctgtatcacg tgctcgcttt gctgtactgg
    21241 aataaattgc tttaaaagga acatatttta cctttttccc aaatgctttg atttcttcgt
    21301 aactttgtgg caaaagcgga gaatcgccat tgctcccttg aaaacgtctt tcctgattcc
    21361 attgtgtctt cccatgtcgg gtaaaatata gttccatacg cagcaaactc ctgtctttct
    21421 tttattttac tctataataa actgtctaat ccagcttgtc attttcatag tgatgcgtca
    21481 attctaaatt agggaatcct tgctggcgaa gtgcttcata cactatcatt gcagctgtat
    21541 tcgataaatt caatgagcgg acatgctcat cattcatagg gatgcgtaaa cacttttctt
    21601 cgttttcacg cataaatgtt tctggcaaac cggttgtttc ttttccaaat aaaaagaagt
    21661 gctcttctcc atcagcaaaa ttttcgtcac tatatacttt atgggcaaat tttgagatca
    21721 aatgtagttt acgattacct aaaaatgtta aaaaagcttc taaattactg tggtaagtaa
    21781 tatttacatc attccaataa tccaaccctg cccgttttag atgtttgtca tcagttgaaa
    21841 aacctagtgg ctcgattaaa tgaagcggag tattcgtggc tgcacacgta cgggcaatat
    21901 ttccagtgtt tgcagggatt aatggttcaa ataaaacgat atgattcatc aggatcattc
    21961 ctctcatatt tatgttcgtt tctattttct gacaatttga tttttgcata aaaaaaaacg
    22021 tatcaactcg gtgtcagtca ctgcgagtcg ttacgttagt gaagctcttc tcactaactt
    22081 ttatcagaac aggaacctga taaaaaccaa tgaaaaaaca acttgttgct aatataacac
    22141 cctcaacttt tttttgcaac ctctactcat taaaaactgc tagaaaaacg ttttctctta
    22201 gttcctttta ataattctat gtcaattgta atcttcttca aaggattctt atataagtct
    22261 gctttgattc gctcttctac ctgccattct aaaggtgaca tggccaaaag atctttttga
    22321 ttttcctctg gtatctcaaa ttcataggtt acacgctgac gttcagttaa tttcattgct
    22381 tcagcaaact tggctactac acgttcattg gaataactct gtttttcagg ttgattcgga
    22441 taaaaagcct gacgtagttc ctttaaataa ttttcttgtg gcaccacctt caacacttct
    22501 ccatcttctg agagtacacg ttggaattct tggtaatgag aaggcgaaaa gatatttaaa
    22561 accgcgttga atgtttgatc agcaaacggc aaattggtca aatcagctac acaccaaaat
    22621 gcttcggcag attgttctgt agctgcgtag actccttctt ttgaaatatc aaatccaaca
    22681 gcattttgaa tctttttcaa ttttgaaagt tcattcaaga agctaccttc tccgcagcca
    22741 acatctaata gcgagacttc ttcaggtaaa tgctgcgcaa tagtctcaat aacgggctga
    22801 tacatgccag attggatcat tctacgcctt ggaacgaaca ttccttgatc gtattctgtt
    22861 ttaaccgcat gggataaaaa ataaagtgtt ccttttttgg aaaggtcaaa acggtgatta
    22921 tttttgcata tcaagccatt atcagacttt tttacttctt cttggcaaac cggacagcgg
    22981 aacagctgat gattttctgc caaaaactgg cgtcctcggt caattttttt taacatagtt
    23041 ccccctcatt tctgttttat cttaccgtta gatgctcact ttggcaactg ctaaaaatat
    23101 gatacaatgc ctagaagaaa gtgaaagata aaggagaaga ttagatgatc aaagaatttt
    23161 gcgctgaaaa ctacacatct attcctctag caattgctag aggagccgat cggatcgaat
    23221 tgtgtgacaa cttagcggtc ggtggcacaa ccccgagtac tggtgtgatc gaagaaacgt
    23281 taagttatgc tggggaaaaa gatatccccg taatgacgat tattcgtcct agagggggcg
    23341 acttcgtcta taacgatatc gaattgaaaa tcatgcatac tgatttgatt gaagcaaaga
    23401 aattagggac ggatggcgta gtatttggtt gtcttactcc ttcaggctgg ctagacgaag
    23461 aggccttaga actattgatc gaaacagcag aagggttgca gatcaccttc catatggctt
    23521 ttgacagtat tcctgaagat cggcaattcg aagcaatcga ttggctggta gaacatggtg
    23581 ttgaccgtat cttgactcat ggcggtcctg ctgacaaaac tattgtagaa aatttcccac
    23641 ggcttaaaga attgattgcc tatacagatg gccgcttaat cattttgcct ggtggtggtg
    23701 tcactgcaga gaatgcagca catgtagcta aagaattgaa cgtaagcgaa gtacacggaa
    23761 ccaaaatcgt ggatcttcag ttataatctt ataaacaaaa aaacatttgc aacaggcata
    23821 atgcttattg caaatgtttt tgttttttta cataaaatag cccataaata aagaagcaat
    23881 attgaaataa atcagtacac tcgtcaaatc gctcaaagtc gtgataaagg gaccgcttgc
    23941 tactgctgga tcaaatccta gacgatccat tagcatcggg attaaactac ctgcaagatt
    24001 cgccactgtg attgcaaata gcatagccat ccctatgaca aaccccaaga taaaattatg
    24061 tttccaaaaa cctacgatta gaaaaatcgt gatccccgta acagctcctg tgacaacgcc
    24121 ggtcaagact tcagccaaaa caagtcgaac aaatccatga tctttctcat cagaaatcgc
    24181 aagtcgacga acagccacag ctagcgactg ggttccagca ttaccggcag ttcctgtaat
    24241 cagcgaaatg aagactgcta aaatactcgc ttcacttacc aagtcttcat agtgactgat
    24301 taaagaagcg gtcgacatac ctaaaaacaa cagagtgatc agccaaggca aacgtcgaga
    24361 cgctgccttt actggatttt cattaatttc ttccacattg accccggcaa gtcctgaata
    24421 atcgctagca gcttcatcat caataacgtc gatgatatca tcgactgtga cgattcctaa
    24481 caaatgatca tcataatcgg taacaggaag agctaagaag tcataatctc taaatgtttg
    24541 tgccacatct tcttggtcgt cgcctacatg aactgaaagc actcgttcgc tcatcagatc
    24601 agaaatcatt gcgtcgtcat cattcacgat taggtcgcgc agagaaataa cccctactag
    24661 ctgaccttct tgattaacga catagatgta atagattgtt tcagctacat ctgcttcgtt
    24721 cttcagcacg tacatcgcag agcgaacagt ttgattggct acgatcgaaa caaattcagt
    24781 tgtcatgatc gcgccagccg tttcatcctc gtaatggaga agttccttga tttcactggc
    24841 atcgtctgcc gacatcaaac ttaaatattt agcaatttgc tttttatcca gcgtattaag
    24901 caagtcaaca gcattatctg tatacatctc agaaagcata tcagctgcat agctaggacg
    24961 catttcatct aggtattctt tcatatgttc gttgtcttct tcaatcacat cgaacatatc
    25021 cgctaattct ttaggcgaca gataggaata gatcagctgc ctgttctctt ctgtaagaga
    25081 ttggtagaat tgcccctgct catagatatg catctctaaa aaactgtttc tgaatgcctg
    25141 aatattattt tcccttaaat cttgagtcaa ctgggcaaat ctttcctcta attcttgatt
    25201 ttcatccaaa ccaatctcac ctcgccttat tcttcaaacc gtctcacaac tgcctccatg
    25261 tctgcggcta aaggctgctt gaactccagc aactcttctg taaatggatg gtaaaaacgc
    25321 agatcataac aatgaagggc ttgtcttttt attcccagat ccattcgccc gccatacata
    25381 tcatcaccga gcagggcaca gccaattgcg gaaaaatgaa ctcttatttg atgtgtcctt
    25441 cctgtatgca gctggatatc aactaacgcg atttctgtta gtcgcttctc tatccagtac
    25501 tcagtctgtg ccgaacgtcc ttcatcagag accattcgct tcaatagcga agaataatct
    25561 cgggcgatcg gcaaatcgat atgtccatgt gccgataaat ctgaaagcct tccactgact
    25621 aaggcctgat attttttcac aaacttcttt tcacgaagtt gcatatctaa ttttgcgtgc
    25681 gcaaatccat gctttgcaaa aagcatcaag ccagatgtat cccgatctag tcgcgtcacc
    25741 acatggatta cttggttttc gtaaccttgt tttttataat aagcctttac acgattagcc
    25801 attgtcccat ttggatggta ttgggcagga atagacgaaa cgcctgctgg tttatttact
    25861 accagaacgt gttcatcttc atacacgata tcgatcggtg tttcatccaa aagtacggtt
    25921 tcatgttctc cttcagcagg aatcacaatg gttaccttat catccttagc tagagaaaac
    25981 aagacatttt ctacttgatc attaactttg atttgaccgc cttgaaattt tattttcgct
    26041 aacagaccct ttgagatccc tttttctttt aaaaaatatt ttacttgctg agaatgatct
    26101 ttctcataat cccatgtaaa ctgcatatca atcctcacta ataaaggcat ctttcacacg
    26161 atgccaaaaa tgcatatgtc gataagaagc aaaatggatc cgttcttctg ctattcgata
    26221 ataaattgag cggatatttg cttttgcgac attcaattga tcaaccgtta caagataatc
    26281 ttctgtattt tccaatttta tttctagcca ttcatcatgg gcaatcacga tcggagaacc
    26341 caaagtacga aacactcgat tattcagtga agcaatctct gccaactgaa aggcattgat
    26401 actaggatgg atcacagcac cgccgacact tttattatat gctgtcgaac cagtaggcgt
    26461 agaaatcgtc aatccatctc ctctaaaact ttcaaacagc tcgtttttga tgtatacatc
    26521 ggctaccatc gtacgattgg cccgtttaat cgttgattca ttcagtgcta aaaaatgctg
    26581 gtccggtgtt tcatccaaat aactgatccg aacatccagc aagggataac taacactttg
    26641 ttcccggttc gttcgtaagc tgtctactag ttcttccagc tcgtaatccc gccaatccgt
    26701 gtaaaaccct aaatgacctg tatgcacgcc caagaaacgc acatcattca gacaatgact
    26761 gtagtgatgg aacgccgaca ataatgtgcc gtctccgccg actgagatga ccaattctgg
    26821 ctcatgatca tctcgttgaa tccctgcttg ttctaaaagt gcgttcaaac gttctgtcac
    26881 ttctatagtc tttgcttctt tattatgaac gatcgctact ttcatcccct gcctcctctc
    26941 tttcgctttc tttcttcaaa agcgttcgat agtagacatc atctgatttt cctcttccat
    27001 gggagaataa ccgctgtgct tcttggattt cttcacggat actggacatc tcttcatcca
    27061 actgataggc agcttctgcc gcacgctgaa gtcgttcact catttcttct ggaaaaacgc
    27121 cttgatattt ataattcagc gaatgctcaa tcgttgccca gaaattcatc gcaagagtcc
    27181 gaatctggat ttccgccaaa attttcttct caccgctgat cagctgtaca ggatactcga
    27241 tcaccagatg ataagaacgg tagccacttg cttttttatt tgtgatgtaa tctcgttctt
    27301 ggagaacttt catgtctttt cttttacgga tgatctcaac aacttgatgg atatcttcta
    27361 caaactgaca catgatcctt aacccggcaa tatcagacat ttcttcttct aaacgtccca
    27421 ttggaatatg ccgtaattgt gattttgtta caatactatc gactggcttg actctcccag
    27481 tgacaaattc aatcgggaca tgtcgatttt gttcacggaa ctgtttgcgg atcccccgca
    27541 gtttcacttt caattctgat acagtttgtt catatggtgc taaaaatgct tcccaatctc
    27601 gttccatagc tgatacctct acttcattaa cattcattgt ttattctacc atatatgcaa
    27661 agttttttcg tactcttgat ttatgcattg accaaaaaaa gaaaattagg caaaatagac
    27721 aaaaaggagt cgatcaaatg acacaaatgc ttgaaatcga atataaatct atgctgacaa
    27781 agcaagagta cgagatattc atcgctcact atcaattaac agataaagat ttccgtgtac
    27841 agactaatat ttatttcgat accgttgatg aacagctgaa gaaacaaaat tgtggcctac
    27901 ggatccgttt cgttggtcat caagctgaat atacattaaa aacacctgct gaaaaagggc
    27961 gtctcgaaac aacggatacc tttataacag aagaagcaga agcatttatc ttcgaaaaac
    28021 gtctgcctcg ttcaggcgca gtttttcaaa aactttctga tttgaatatc gatcctgctt
    28081 cattaatcca aaccggaaag cttacaacaa aacgagctga attccctatt gaagaaggac
    28141 ttttagctat tgatgaaagc tggggagaca atctacacga ttttgaactg gaactagagg
    28201 taggggatgc atctgtggga aaaattgctt ttataaattt tttaaaacgt ttttctttac
    28261 cttatcgtcc tgctaagaac aagatccaac gtatgcttga agctaaaaat tagaaacctt
    28321 tcattttcac aaggcacttg agttcatttt tttacttttt tctgttaagt tataggatgt
    28381 gaaagaatct agtcactagt tgtatagaat ctattttggg ggagattcat atgatcgaaa
    28441 tctatttatt tgttaatcct ttaggggaat actgtttcga aatggaacaa cagttattac
    28501 aatttatcga agaagagtac gggacaccat caaaagaaaa gatgcaattt cgctttcttc
    28561 ctttggtcaa tttgcagaca attggggatg tcatgcaaca aaaaggaatt tctcagaaca
    28621 atcttgagga acgtaatcac ttattctcaa tgacttattc tgcagcattg gactgcaaag
    28681 cggcgcagtt tcaaggaaag aaaaaaggcc gccgtttttt gatcaaattg caagaagcag
    28741 tcggctgtaa tgacatacca tattctcaag aacttgctga atccatattt gaagaaatcg
    28801 gcggcgattt gaatatgttt aaagaagatc gtcagtctga cttcgttaaa gaagtattct
    28861 tttctgatca aaaaattgct cgggaaatgg gcatcacaaa acacccttct gcagtcgttt
    28921 acaattatgc ctgcgaccgt gattttggtg ttttagtaga agtaaaaggt acaagtagcc
    28981 tttggagaat cacagagctg tgtaaaacaa cagataactc atatcaagtt tttaatggtg
    29041 aacatttaca tacaaatgat tctcagttcc attcaagaac tagccattta cacttgcttt
    29101 ctaattaaaa
//
LOCUS       DAZKKZ010000035        28091 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.035, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000035 DAZKKZ010000000
VERSION     DAZKKZ010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 28091)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28091)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28091
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.035"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(205..1104)
                     /locus_tag="ACG8LA_001645"
     CDS             complement(205..1104)
                     /locus_tag="ACG8LA_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HFQ0203947.1"
                     /translation="MGKLAIISDLHVDINKFGESELMQLWQVLQKHKITRLHLAGDTA
                     NKVDRCLAVVEFFVNKGLSTTFHFGNHELADVPNEQMMDHFPDPHFLNERYIALNEQT
                     VLLGMNGWYDYQFSELKDYEAIVRMKRLYWYDRFIQRGKTDLEVNAEMLAAAKNLLDQ
                     LEAKKLEVILSTHFVPKRAFIMYQSAPYERWNKLNAFLGSESFGELLDRYSNIKQVVF
                     GHTHRRFEDKSIGHTIYSCRPFGYYYEWQLTRDFVLKEQLLDSYDPMKLRVLLRAHHP
                     AFQAYQTQHLQEEFEQAMTIVPY"
     gene            complement(1114..1470)
                     /locus_tag="ACG8LA_001646"
     CDS             complement(1114..1470)
                     /locus_tag="ACG8LA_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HFQ0203948.1"
                     /translation="MKLEVTKEAQEVLKNKLEADDQLLLDIENGDGPFAESQVSCQLD
                     TAFRLIIVKKDTQTDLSLYSVVADTPVGPIKIKDSAILYMDDPSTLALEPTYNSLQLK
                     GPSGLRKGNLQVVRKD"
     gene            1825..2121
                     /locus_tag="ACG8LA_001647"
     CDS             1825..2121
                     /locus_tag="ACG8LA_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanyl-tRNA synthetase subunit alpha"
                     /protein_id="HFQ0203949.1"
                     /translation="MKEYIKNIYFIEETQNIEGSYIEVKTLFVNEDKTKALDIYKKLA
                     SKKTNSFGLILSEYKIKAEESYFYQLLKRWSKLPADFYRKMQIINYQPLAETHA"
     gene            complement(2765..3718)
                     /locus_tag="ACG8LA_001648"
     CDS             complement(2765..3718)
                     /locus_tag="ACG8LA_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HFQ0203950.1"
                     /translation="MKKLVVGILILASFGLAACGNSNNTSQADTKKSSTQTETTLTIT
                     DSNGDQIEVPNNPEKVVVFDNGSLDTMDALGVGDKVVGAATSSLPEYLSSYKKVESAG
                     GIKEPDLEKINQLQPDLIIISGRQRDFQKDLSQIAPTIFLSLDAKNPWESFQQNVTAL
                     GEIFGKQEEAKTQLEELSSAIDQTKKKAEATDKKALVTLVNEGQLSAYGSGSRFGFIH
                     DLFGFEQADDQIEASTHGQSVSYEYVLEKNPDILFVVDRTKAIGGDDSKDDISANELV
                     AQTNAGKNQQIISLEPDVWYLSGGGLESMKLMIEDVNQAFK"
     gene            complement(3741..4496)
                     /locus_tag="ACG8LA_001649"
     CDS             complement(3741..4496)
                     /locus_tag="ACG8LA_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0203951.1"
                     /translation="MIDLQKVNKLYHGKSVVKDVQLTIPEKKLTAFIGPNGAGKSTVL
                     SMISRLIPKDTGEIYLDHNEVKAWKSNELAKKLSILRQSNEINVQITVKELVEFGRFP
                     YTKGKLTTKDEEIVQESLEHLGLEEIADQSIDTLSGGQLQRAYIAMVLAQDTDYILLD
                     EPLNNLDMNFAVQIMQILKNLVQEIGKTIVIVLHDINFAASYADEIVAMKDGQLFTQG
                     TTQEMIKKDVLDELYEMDIRICEIEGRRFCLYF"
     gene            complement(4493..5452)
                     /locus_tag="ACG8LA_001650"
     CDS             complement(4493..5452)
                     /locus_tag="ACG8LA_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HFQ0203952.1"
                     /translation="MLKKKPSIFIGMLVLVLFVTGMYLTIHTYGNWHFACALRSKKIF
                     AFILVSLAVSSATISFQTITHNQFLTPSVLGLESLYVLVQTVLFFFIGGVTMLQQTGT
                     VFFLLNVGLMVGLSLLLFFFLLKKMRANLFLLLMSGMILGTLFGSVSTFLQVIMDPNE
                     YDLLQGRLFASFGNIQSQYLLPASLIIIGCWYLLFRYRHVLDVFHLGNEQAVNLGIDT
                     DRFEFLILCCVSLLTGTSTALVGPVTFLGFIVANISYRVFSTYRHGQLFIGSFLVAML
                     FLTGGQLAVEQIFGWNTTVSVVVEFVGGIYFVTKLIRERKSIL"
     gene            complement(5445..6395)
                     /locus_tag="ACG8LA_001651"
     CDS             complement(5445..6395)
                     /locus_tag="ACG8LA_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HFQ0203953.1"
                     /translation="MRYGRLVALLVILSSISLFIGVSNVQLSELLQLDGQSLQILLVT
                     RLPRTICLILVGATSSICGLIMQHLTQNKFVSPTTAGTMDSARLGILVAMIFLPGASL
                     IVRSLTAFCFAFAGTLLFLSLTRLFLQKNQLMLPLIGVMLGNIIGSVATFFAYQFQLV
                     QNMTSWLQGNFATVIRGNYELLYAVVPLLLLVWLFAYRFTIIGLGESFAVNLGIDYQK
                     MQFLGIGLVSLASAVMLIMVGSIPFIGVIIPNLVSRIYGDQVHKTIGVTALAGSLFLV
                     FCDLVARVLIFPYEIPVSVIVGIIGGAIFLYLLIRGRRYA"
     gene            6545..6997
                     /locus_tag="ACG8LA_001652"
     CDS             6545..6997
                     /locus_tag="ACG8LA_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HFQ0203954.1"
                     /translation="MAQDDVKSHLDKGLYGTPLVNPEEQHKYLGTFRERCYLSMTVAE
                     MIQPKNKENFLKELKKHPDASILLNGALPLSVQNQYIQLATKNNSRFTVVNDYVTANP
                     EEFGLLLTAKEAVNEPVIDIEKKYPEENSSPAEKEKPKKKKSFWDRLF"
     gene            complement(7086..9353)
                     /gene="gshAB"
                     /locus_tag="ACG8LA_001653"
     CDS             complement(7086..9353)
                     /gene="gshAB"
                     /locus_tag="ACG8LA_001653"
                     /EC_number="6.3.2.2"
                     /EC_number="6.3.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004357 - glutamate-cysteine ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006750 - glutathione biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutamate--cysteine ligase
                     GshA/glutathione synthetase GshB"
                     /protein_id="HFQ0203955.1"
                     /translation="MMNFKQLLLHVNARPFIDQARFGIEREGQRVDLAGNLAKTDHPA
                     IFGDRSYHPYIQTDFSETQTEMITPVTDSIPELFQYLAAVYDVTARSIPKEEMIWPLS
                     MPPALPEKDEEIIIAKLKNFEDVLYRRYLAKKYGKRKQMVSGIHFNFEFGDELLRTLF
                     SHQEEFQDFSEFKTELYLKTARNFMRYRWMITYLFGASPMSEKNYFLDESHPQEPVRS
                     IRNSALGYTNHPNVKVSYASMKQYLADIERMIEEGKLSEEKEFYTPLRFRGGKKVADL
                     ATTGVRYIELRNIDLNPYARLGINPEQVRFLQLFLMYMLWTEEKEDCDQWVAEGTTRN
                     NKVALEQPSDQTEFHQEGREILEGMKQMLVELDWLDSLYLVEEALTQMDHPEQTLAAK
                     LYQEAQLSSQQEVAVALGHQYYKESHERPYQLAGFREMELSTQIFMFDAIQKGVQVKV
                     LDESDQFLRLQFQDHVEYVKNANMTSKDSYIVPLIMENKTVTKKVLKEAGFRVPGGAE
                     FSSMEEAVKAYPRFAEQAFVIKPKSTNYGLGITIFKEGASLEDYQAGLAIAFREDSSV
                     LVEEFMPGTEYRFFVIDGEVQAIMLRVPANVIGDSIRTVKELVEEKNSDPLRGTNHRA
                     PLELIQLGELEQLMLKEQGLTIESVPQANQIVYLRENSNISTGGDSIDMTDEFSEAYK
                     KIAVSAVEALGAKISGIDLIIPDKEIDPTTDKKAYGIIEANFNPAMHMHVYPFAGKGR
                     RLTMNVLKLLYPEVF"
     gene            complement(9540..10538)
                     /gene="ftsY"
                     /locus_tag="ACG8LA_001654"
     CDS             complement(9540..10538)
                     /gene="ftsY"
                     /locus_tag="ACG8LA_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005047 - signal recognition particle
                     binding [Evidence IEA];
                     GO_process: GO:0006614 - SRP-dependent cotranslational
                     protein targeting to membrane [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HFQ0203956.1"
                     /translation="MGFFDKIKRAFTGEEKTEEVEVQEKYDKGLEKTRKTFGERMNEL
                     FANFRTVDEDFFEELEETLIGADVGFETAIRITEALRQEVKLRNAKKSAEVQNAIIEK
                     LVDLYEAEGINEVNELNIQEDGLTVILFVGVNGVGKTTSIGKLAHQFKNEGKKVLMAA
                     ADTFRAGAIDQLVVWGERAGVEVVRGNAGGDPAAVVFDALERAKTEQADVLLVDTAGR
                     LQNKVNLMNELEKIKRVIQRELPEAPQETLLVLDATTGQNAMVQAKQFKETTDVTGLV
                     LTKLDGTAKGGIVLAIRNELHLPVKLVGLGEGIDDLEPFDPNDFVVGLFKGLLKEE"
     gene            complement(10549..11358)
                     /locus_tag="ACG8LA_001655"
     CDS             complement(10549..11358)
                     /locus_tag="ACG8LA_001655"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFQ0203957.1"
                     /translation="MIKLVAIDLDGTLLNEQKLISDENKQALAQAKQQGVKIVLCTGR
                     PLAAMAHYLQELGLVDEGDYSITFNGGLVQKNDTGEIMEKKVMEVSDIQRLYKLAQQL
                     DLPLDVLSDNVVLQLPSAPRKQSLYNVLNKLLQFQPADISDITDEFVLNKAVIAYDQE
                     ELDPKIKEIPAEFHEMYEIIKTRSMLLEFMPKGVTKAYGISLLAKDLGLKQEEIMAIG
                     DEENDLPMIQYAGLGVAMENAVPFVKEAADFVTASNEENGVAKVIQKFVLE"
     gene            complement(11367..14948)
                     /gene="smc"
                     /locus_tag="ACG8LA_001656"
     CDS             complement(11367..14948)
                     /gene="smc"
                     /locus_tag="ACG8LA_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA];
                     GO_process: GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HFQ0203958.1"
                     /translation="MYLKRIEIAGFKSFADKTVIDFENSVTAVVGPNGSGKSNITEAI
                     RWVLGEQSAKSLRGGKMPDIIFAGSDTRKQLNIAEVTVILDNSDHYLPLEYNEISVTR
                     RYRRTGESEFFINKQSCRLKDIQELFLDSGLGKESFSIISQGKVEAIFSSKPEDRRGI
                     FEEAAGVLKYKQRKKKAEQKLFETEDNLSRVQDIIHELEEQLTPLAAQSEAAKEFLRL
                     KETLTQTDVSLMVAEIKTAKKDWDNKQAQLAKFNLELGKLSESIQEQESILAKQRKEN
                     AQADRLIEKNQQVLLDLSEKLKQTEGQKDVLQERTKHTQKSSQEYQTSLAEAQKKVKH
                     FEKLQESLMKAAAEKETEIQKAEANLIKTQQELEKYQKSTKELLAELRDQYVDLMQEQ
                     AAVGNELKYLERQYIQETAKSKQTLAKQSEVEASVDRLILQKEELTQKQAQLKSSLTE
                     TKEKLEMIQQNGKKFQEALAKEQPKMYQLMNQVQQLRARKKSLQEIQENYFGFYQGVR
                     LVLQHKQQLSGIVGAVAELIDVPADFTLAIEAALGGAAQHVIVENEKDARQAITYLKQ
                     QRGGRATFLPLTTIKPRQLPAHILTQAAAVEGFIGIASEQVSYPDQIQTVVQNLLGTI
                     LLAKDLTSANAIAQTIRYQYRVVSLEGDVMNAGGSMTGGANKRGNQGSLFVQNQELKQ
                     LTSEFEEADKQLQAQEKKVQELQQETARLAEEQEVLRTRGEQLRFEEQEATNQLQNII
                     NELERFEKEKQISTFETRELQQFIEDYEKQTNELKDKQTDLESQRQKIDEEIKSLSQE
                     SDQMEARRAQVQSQKAQEQADLAVLKEQFNHLQIQLRGARVQKAEATERQEAIEKQLA
                     TLTADFSDHEVTEESLEKQINELSAQRETLKAELAKAKEQRDRRQKEIDKLEAVLAER
                     NREQKARLSEQSKLEVQKDRAEMILDNHLTYLQSEYQLTFEKASQDYQETTDIEDSRT
                     KVSSLKEQIEKLGPVNLNSIEQYEQVSERHTFLATQRDDLLAAKNQLFETMDEMDDEV
                     RTRFKEVFEAIRQEFKIVFPNMFGGGKAELVLTEPTDLLKTGIEIEVQPPGKKLQSLS
                     LLSGGERALTAIALLFSIIRVCPVPFCILDEVEAALDEANVKRFGRYLSDFQDDTQFI
                     VVTHRKGTMVAADVLYGVTMQESGVSKIVSVRMEDINEEAKINETKV"
     gene            complement(14968..15654)
                     /gene="rnc"
                     /locus_tag="ACG8LA_001657"
     CDS             complement(14968..15654)
                     /gene="rnc"
                     /locus_tag="ACG8LA_001657"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004525 - ribonuclease III activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HFQ0203959.1"
                     /translation="MDNQLTKELKENYNIVFHDLNLLEQAFTHSSYVNEHRNLQLSDN
                     ERLEFLGDAVLELMVSQYLFRLYPHLPEGKLTKTRAAIVREDSLSKFAKECHFDQYVL
                     LGKGEENSGGRTRPALLCDLFEAFLGALYLDQGFDTTHAFIEKVIFPKVKAGAFSHEM
                     DHKTKLQEVLQKSGDVSIEYRLINEEGPAHERVFWIEVYVDDQLIGTGQGKSKKLAEQ
                     AAAENALAAL"
     gene            complement(16002..17783)
                     /locus_tag="ACG8LA_001658"
     CDS             complement(16002..17783)
                     /locus_tag="ACG8LA_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HFQ0203960.1"
                     /translation="MKKTIFGFAALMSAVVLAACGGGGTDTSGNNSGGNGNNKEELTF
                     PIATKNNDDAIEDGELEAAVATDSQFKGLFQWEFYQDSYDAAFMAPSHEPLFANDDDF
                     RITDDGAATLDLDEDTKKATIKVKDNVKWSDGEDVTADDVIFPYEIIGNKDYTGIRYD
                     DTFRNIVGMEEYHDGSADTISGIKKIDDKTVEIEYKEVNPSMLQSGGGIWSYAAPKHT
                     LEGVAIKDMESSDQVRKNPVTFGPYYMSNIVAGESVEYLPNEHYWNGTPKLKKITMKS
                     VPMASATEALNSKLYDMIFQMPTDTYDTYKEIAGYTNLGREQTSYTYLGFKLGKWNAD
                     TKSVEYNPDSKMADKSLRQAMGYALDNNAVGERFYAGLRSNATSLIPPVFQSYHDDEM
                     KGFTQDLDKAKKLLDDAGYKDVDDDGLREDKDGNKLTINFASMSGGETAQPLADYYIQ
                     QWKEIGLDVQYTTGRLIEFNSFYDKLENDDPEIDVYQAAWNTGTDPNPSGLWGPNAAF
                     NYTRYESEENTKLINDISSSKAFDEEYQKEAYQKWQQYAFEEAFAIPTLFRNEVLPVN
                     DRVKDWDWSYDVPNPWANVSVTADSRS"
     gene            complement(17809..18723)
                     /locus_tag="ACG8LA_001659"
     CDS             complement(17809..18723)
                     /locus_tag="ACG8LA_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFQ0203961.1"
                     /translation="MSEKNNTAVQESIPPMGIRMIAREFKKDKIAIFSLGLLVVLLLV
                     IFIGAMLTDQDKVMYVSIFDKYAAPGTVSTQGQKFILGADEGGRDVLGQLIIGARNSV
                     TIGFAITILTSIIGVGLGIISGYYGGIIDNILMRIVDFIMILPIMLIIIVFVSIISRY
                     NVWSFIFIMSAFYWVAKARLFRSKTLSEARRDYVSASKTMGTNDFKIMFREIMPNLSS
                     LIITNLTMNFAANIGIETTLTFLGFGLPANVPSLGTLIGYASNGEVLVNRQWIWLPAS
                     ILILVLMLSINYVGQAFKRSADARQRLG"
     gene            complement(18750..19712)
                     /gene="opp4B"
                     /locus_tag="ACG8LA_001660"
     CDS             complement(18750..19712)
                     /gene="opp4B"
                     /locus_tag="ACG8LA_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter permease"
                     /protein_id="HFQ0203962.1"
                     /translation="MWKTILRRVLLMIPQVIILSVLIFLLAQAMPGDPFTGLINPNQD
                     PAVIEQMRQAAGLNDPWYVQYFRWIGNALQGDFGQSFLYKRSVADLIGERIINTLYLS
                     ILTVVLTYLIAVPLGMLAGRYQNSILDKIVVIYNFFSFAVPLFIFGLIMLFVFGYRLG
                     WFPTSGSQTLGLQGGFITQWIDRLKYILLPSITQAFLATAVTIQYLRSEVIDSKSLDF
                     VRTARSKGVPTNKVFSRHIFRNAALPMASQMGYEITSLIAGSVVIEKIFGYPGVGKLF
                     IDSIGQRDYTVITSLVLILGIATLVGTLLSDIIMSIVDPRIRIQ"
     gene            complement(19712..20656)
                     /locus_tag="ACG8LA_001661"
     CDS             complement(19712..20656)
                     /locus_tag="ACG8LA_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0203963.1"
                     /translation="MTELITIKDLKVHYPIRSGFFNRVTDHVYAVDGVDFIIEKGKTY
                     GLVGESGSGKSTTGKAVVGLEKVTAGQIMYEGKDVTKRSNRKKMGYNKDVQMIFQDSM
                     SSLNPKKRVLDIIAEPIRNFERLSDQEEKKKVKGLLDIVGMPEDALYKYPHEFSGGQR
                     QRLGVARAVATNPKLIVADEPVSALDLSVQAQVLNFMKRIQQEYGLSYLFISHDLGVV
                     KHMCDNIAIMYKGRFVEIGTREDIYNDPRHIYTKRLLSAIPQIDVENRESHKENRRRV
                     EQEYIQNQKEYYDATGRVYDLRTITTTHKVALKDGGAS"
     gene            complement(20657..21661)
                     /locus_tag="ACG8LA_001662"
     CDS             complement(20657..21661)
                     /locus_tag="ACG8LA_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0203964.1"
                     /translation="MSDNQLLEVQNLHTGFRLKDDYYDAVDDVSFTLDKNEILAIVGE
                     SGCGKSTLATTIMGLLDPNNTKITGEILYNDLNLIDLNETLYNKIRGNDIGMIFQDPL
                     SALNPLMRIEDQIKEGLSYHTKMNAEQRQARALELLEQVGIPNPARVGRQYPHELSGG
                     MRQRVIIAIAIACKPPIVIADEPTTALDVTIQAQILDLLKDLQEETKTGIILITHDLG
                     VVAEMADRVAVMYGGQFVEVAGVKELFDHPKHPYTRSLLNSIPQEGNHDAELHVIEGV
                     VPSLKNMPRKGCRFAPRIPWIPASDHEEEPILHEVAPNHLVRCSCYKHFHFRDEKGEV
                     "
     gene            complement(21929..22171)
                     /gene="acpP"
                     /locus_tag="ACG8LA_001663"
     CDS             complement(21929..22171)
                     /gene="acpP"
                     /locus_tag="ACG8LA_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000036 - acyl carrier activity [Evidence
                     IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HFQ0203965.1"
                     /translation="MTREEVFNKVAKIISNHFEIDTDKVTDELNIKDDLKADSISIME
                     FVLELEDEFGTEISDEDAEQIETVGGAVDYISSHLK"
     gene            complement(22293..23294)
                     /gene="plsX"
                     /locus_tag="ACG8LA_001664"
     CDS             complement(22293..23294)
                     /gene="plsX"
                     /locus_tag="ACG8LA_001664"
                     /EC_number="2.3.1.274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043811 - phosphate:acyl-[acyl carrier
                     protein] acyltransferase activity [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HFQ0203966.1"
                     /translation="MKIAVDAMGGDHAPQAIVEGVALAQQDFPEVEFLLYGKEAEIKK
                     YLTNEKNITIIHTDEKINSDDEPVKAIRRKKTASMVLAAQAVKNGEADAVFSAGNTGA
                     LLAAGLFIVGRIKNIERPGLMSTLPVVGKEGAGFDMLDLGANAENKPEHLLQYGILGS
                     FYARKVRGIGRPRVALLNNGTEATKGSEVTKKAYELLQNETSLNFIGNVEARELLNGV
                     ADVVVTDGFTGNAVLKSIEGTAMNMMNLLKSAILNEGIKGKMGAMLLKDGLRSLKAEM
                     DYSKHGGAVLFGLKAPVIKTHGATGPDAVRYTIRQIHTMLETDVVGQLVEQFEKSEE"
     gene            complement(23343..25379)
                     /gene="recG"
                     /locus_tag="ACG8LA_001665"
     CDS             complement(23343..25379)
                     /gene="recG"
                     /locus_tag="ACG8LA_001665"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HFQ0203967.1"
                     /translation="MRSLDDPITMLAGVGEKRAASLASLGIQTIEDLLTYYPFRYEDI
                     QERNLNEIQDQEKVTLKGIVVSPPVMNRFGYKKSRLQFRMMQEHDVFNVSFFNQPYLK
                     EKVILSEEIAVYGKWDAKRKALNGMKILGSQTMDDFSPIYHVNKSIRQTTLVDLIKKG
                     FQEYGTLIEENLPNNLVEKYRLLDRASAVRSMHFPKDHEENHQAKRRVVFEEFFLFQM
                     RLQGLKKAEKAETNGLEILYDVQKLKEFTQKLPFELTNAQKRVTNEICRDLRSPQHMQ
                     RLLQGDVGSGKTVVAAIALYATVTAGFQGALMVPTEILAQQHMESLQQLFDPNEVTIA
                     LLTGSTKAKERRELLEKLEQGEINIVIGTHALIQDGVEFQNLGLVITDEQHRFGVNQR
                     KVLREKGWRPDVLFMTATPIPRTLAITAYGEMDVSIIDELPAGRIPIETRWVRTPQLD
                     SVLDWTKKELARGHQMYVICPLIEESEALDVKNAVEIYEKLRELFAPKYEVGLLHGKM
                     KNQEKEVIMEAFKDNQMQILVSTTVIEVGVNVPNATVMLIMDADRFGLAQLHQLRGRV
                     GRGSDASYCILVANPKNELGVERMKIMTETTNGFVLSEKDLELRGPGEVFGFRQSGLP
                     QFAIADLVTDGNVLEVAREEAAALWQIKDWQMLPEYQPLAQSLQIENQDNRYFD"
     gene            complement(25496..27178)
                     /locus_tag="ACG8LA_001666"
     CDS             complement(25496..27178)
                     /locus_tag="ACG8LA_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HFQ0203968.1"
                     /translation="MSVTEISASQFQEMVQAGANRLQVNAEYVNSLNVFPVPDGDTGT
                     NMNLSMTSGAKAVVDSTSEKVGELAAMLSKGLLMGARGNSGVILSQLFRGFSKQIPDV
                     VSLNASDLAAAFTHGVETAYKAVMKPVEGTILTVAREAAKAGEKKAKSTDDVVEVMTA
                     VVKGAKRALAKTPDLLPVLKEVGVVDSGGQGLLFVYEGFLSALNGEFQADETYEPSPA
                     EMDDMVNAEHHRSVQGQMATEDIHFGYCTEIMVKIGEGPTVDSTFDYEEFRNYLDGIG
                     DSLLVVNDDEIIKVHVHTENPGEVLNYGQKFGSLVKIKVDNMRLQHETILEHDEEVNE
                     FAKKETPRIPYGIVAIAAGKGVQELFESLGANYVISGGQTMNPSTEDIVKAIQEVNAD
                     KVIVLPNNKNIFMAADQAAEVADIPVAVVPSRTISQGLTAMLSFNDQASLEENKETMT
                     EMLSSVVSGQVTHAIRDTSIDGVEIKEGDFLGMIDGKILISNPDITATALSTLEQMIN
                     EDTEIVTILAGDEGTVEQANEFAEKLTEKHPDLEIEIHQGDQPVYPYLFSAE"
     gene            complement(27230..27592)
                     /locus_tag="ACG8LA_001667"
     CDS             complement(27230..27592)
                     /locus_tag="ACG8LA_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HFQ0203969.1"
                     /translation="MAVKIQTSAGTIEITNDVIATVVGGAATDVFGVVGMASKNQIKD
                     NITEILRKENYSRGVVVRQEDNGIAVDVYTIISYGTKISEVSRNVQEKVKYNLEALLG
                     VTANSVNVFVQGVRVLPD"
     gene            27862..28050
                     /gene="rpmB"
                     /locus_tag="ACG8LA_001668"
     CDS             27862..28050
                     /gene="rpmB"
                     /locus_tag="ACG8LA_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HFQ0203970.1"
                     /translation="MAKVCYFTGRKTKSGNNRSHAMNSTKRTVKPNLQKVRVMVDGKP
                     KKVWVSTRALKSGKVERV"
BASE COUNT         7767 a         6079 c         4950 g         9295 t
ORIGIN      
        1 tatatttttt tttgtgatta tcgttcaaaa aaagaataca cgcttgcatc tagtactctg
       61 cgagttacaa atcatccgat caaataaaca ttcgctgatt attttccgca aaaaaagcag
      121 catatccacg ataaatggat ctactgctct tacttatcct tatgttttac aaggtatttt
      181 cttttacaca ttactaatgc tgtctcaata cggaacgatt gtcatcgctt gttcaaattc
      241 ctcttgcaaa tgttgtgttt gataggcctg aaaagctggg tgatgggcac gcaagaggac
      301 acgtaatttc ataggatcat agctgtctag caactgttct ttcaagacaa aatctcgggt
      361 cagctgccat tcataataat aaccaaaagg tctgcagctg taaatcgtgt gaccgatgga
      421 tttatcttca aagcgacgat gcgtatggcc aaaaactact tgtttgatat ttgaataacg
      481 gtcaagtaat tctccgaatg attctgatcc taaaaatgca tttaatttgt tccaacgctc
      541 ataaggagca gattgataca tgataaatgc ccgtttagga acgaaatgag tggataaaat
      601 cacctcaagt ttttttgctt ccagctggtc tagcaaattt tttgcagctg caagcatttc
      661 tgcattgacc tcgagatctg ttttcccacg ctggatgaac cgatcatacc aatacaaacg
      721 cttcattcgt acgattgcct cgtaatcttt caattcggaa aactgatagt cgtaccagcc
      781 attcatccct aaaagaacgg tctgctcatt taaagcaata taccgttcat ttaaaaaatg
      841 tgggtctgga aaatggtcca tcatctgttc attgggcaca tctgccaact cgtgattgcc
      901 gaaatgaaat gtcgtagata atcctttatt gacgaaaaat tcgacaacag ctaggcaacg
      961 gtctacttta ttagccgtat ctccggctag atgaagccga gtgatcttgt gcttttgcaa
     1021 aacttgccaa agctgcatca gctctgattc gccgaattta ttgatgtcca catgtaggtc
     1081 gctgatgatc gccaattttc ccattttatc cctctagtct tttcgaacaa cttgcaagtt
     1141 gccttttctc aagccgcttg gtccttttaa ttgtaaacta ttataagttg gttctaaagc
     1201 aagtgtggat ggatcatcca tgtaaagtat tgcactgtct ttgattttga ttggtccaac
     1261 tggtgtatca gccactacag aataaagact tagatctgtt tgtgtatctt ttttgacaat
     1321 gatcaatcga aatgccgtat ccaattggca actgacttgg ctttctgcaa atggaccgtc
     1381 accgttttcg atatctaata aaagttgatc gtctgcttct aatttattct tcaatacttc
     1441 ttgtgcttct tttgtcactt ctaatttcat ctgtatcacc tcatgtcata gaataatcac
     1501 tttattcatc agatgcaact aatttgtctg gttctgactg ttctcaattt attggaaagt
     1561 aagtcattcg tttattatga tttctcttat cacaaaagag acaactttcc cttttcttcg
     1621 ttcagtttct tgaacggaaa aagacccaaa aagcaacctg ttatttgttt aaccttattc
     1681 ctttcttaaa taacaaaaaa tactataaaa aataaaaaac ctttaacaac tattggaaaa
     1741 agaattactt tttgttcacg gattattaac aactcttcgg tagagtaaac ttatcaaata
     1801 aaagacttct ttggaggaat cactatgaag gaatatataa aaaacatcta ttttatcgaa
     1861 gaaacacaaa atatcgaggg ttcttatatt gaagtaaaaa cactctttgt caatgaagat
     1921 aaaaccaaag cattggatat ttataaaaaa ttagcttcaa aaaaaacgaa tagttttgga
     1981 ttgatattaa gcgagtataa aatcaaagca gaagagagtt atttctatca attactaaaa
     2041 cggtggagta agcttcccgc cgatttttat cgaaaaatgc agatcatcaa ctatcaaccg
     2101 cttgctgaga cacatgccta aatagaggtt gtgaaatcag tgctttgagc taataccgaa
     2161 ggtcagctga ttgaacattg tttagaagag attgtgacaa ctgcgatttg ctttgagtaa
     2221 taagaacgct ggacagaaaa tagcttctca tattttctag tctagtgggc ttattgccga
     2281 gaagcagcag atggaacatc gtttagaaga gattgtgaca actgcgattt gttttgagta
     2341 ataagaacgc tggacagaaa atagcttctc atattttcta gtctagtgga cttattgccg
     2401 agaagcagca gatggaacat cgtttaaaga agagatcggt acaaaataaa aatatctaaa
     2461 tttaagtttt atctaagttt cgctttgtac ctttgattca aatcaaagga ggcgatcttg
     2521 atgctgaaaa aatggatcac actatttttt gccactcccc attctagaat caacccgtat
     2581 gatgtagata atgaattcac gttgaaaaaa gatttctcaa ataaataaaa accatccgta
     2641 aaatcatcaa tacgatttta cggatggttt ttgataactt ctttgaggat aggctcttgc
     2701 tatttaagaa tgtaagaaac attattgtta catagtatga gagtttaatc ctctgttatt
     2761 tatgctattt aaatgcttga ttcacatctt cgatcatcag tttcattgat tctaaaccgc
     2821 ccccgcttaa ataccagaca tctggttcaa gggagatgat ctgctgattt ttaccagcat
     2881 tcgtttgtgc taccagttca ttggcagaaa tatcatcttt gctgtcgtct ccaccaatag
     2941 cttttgttct gtctactaca aataagatat ccggattttt ttccagcaca tattcataag
     3001 aaacactttg accgtgagtg gatgcttcga tttgatcatc tgcttgttca aagccaaata
     3061 aatcatggat gaaaccgaat ctagaaccag atccgtaggc tgataattgc ccttcattca
     3121 caagtgtgac tagtgctttt ttgtcagtag cttctgcttt ctttttcgtc tgatcgattg
     3181 cactagataa ttcctctaat tgagttttag cttcttcttg cttaccaaag atctccccta
     3241 aagcagtgac attttgctgg aaagattccc atggattttt cgcatctaaa gaaaggaaaa
     3301 tggtcggagc aatttgactt agatcttttt gaaaatctct ttgtcggcca gaaatgatga
     3361 ttagatctgg ctgaagctga ttaatttttt ctaagtctgg ttcttttatt ccacctgctg
     3421 attctacttt tttataggat gaaagatact caggaaggct gcttgtagct gctccaacta
     3481 ccttatctcc aacaccaaga gcatccatcg tatctaaaga accattgtcg aatacgacga
     3541 ctttttctgg attatttggc acctcgattt ggtctccatt actatctgtt atcgtcaatg
     3601 tagtttcagt ttgtgtgctg cttttttttg tgtctgcctg actggtgttg ttgctatttc
     3661 cacatgctgc taaaccaaat gatgctagaa tcaagatacc tactactaat tttttcatct
     3721 cttctctcct aatgttagtt ttagaaataa agacagaatc tgcggccttc aatctcacaa
     3781 atccgtatgt ccatttcgta taattcatcc aatacatctt tttttatcat ttcttgggtc
     3841 gttccttgcg taaataactg tccatctttc attgcaacaa tttcgtctgc ataacttgca
     3901 gcaaagttga tatcatgaag aacaataaca attgttttcc cgatttcttg tactaaattt
     3961 tttaaaatct gcatgatttg aaccgcaaaa ttcatatcta gattgttcaa aggttcatcc
     4021 agtaaaatat aatccgtgtc ttgcgctagc accattgcaa tatacgcacg ttggagttga
     4081 ccgcctgaaa gagtgtcaat cgattgatcc gctatttctt ctaacccaag gtgttccagt
     4141 gattcctgaa cgatttcctc gtcttttgtc gtcaattttc ctttcgtata aggaaatcgt
     4201 ccaaattcta ctaattcttt cacggtgatt tggacattta tttcattcga ttgtcgtagg
     4261 atcgataatt ttttggctaa ttcattggat ttccaagcct ttacttcgtt atggtctaaa
     4321 tagatttcac ctgtatcttt tggtatcaaa cgactgatca tcgacaacac cgttgacttt
     4381 ccagcaccat ttggaccgat aaaagcagtc aacttctttt caggaatcgt taactgtaca
     4441 tctttaacca ctgattttcc atggtacagt ttattgacct tttgtaaatc aatcatagga
     4501 tactcttcct ttcgcgaatc aattttgtga caaaataaat tcctccgaca aattcaacga
     4561 cgacactcac tgttgtattc cagccgaaaa tctgctctac tgcgagctgt cctcctgtca
     4621 gaaacagcat agctaccaga aagcttccga taaatagctg accatgacga taagtagaaa
     4681 agacacgata actgatattt gcgacaataa accctaaaaa agtaactgga cccacaagag
     4741 ccgttgatgt ccctgtcaaa agactgacac aacataaaat caaaaattca aaacgatctg
     4801 tgtctatccc gaggtttact gcttgttcat ttccgagatg gaaaacgtct agcacatgtc
     4861 gatatcgaaa taacaggtac cagcagccga taatgatcaa agaagcaggc aaaagatact
     4921 gactctggat attgccaaag cttgcaaata atctgccttg aagcaaatca tattcattcg
     4981 gatccatgat gacttgtaaa aaggtactga cactaccaaa aagcgtacct aaaatcatcc
     5041 ctgacatcag taataaaaaa agattcgctc tcattttttt caaaagaaag aaaaataaca
     5101 atagactcag cccgaccatc agcccaacgt tcaataagaa aaaaactgta cctgtctgct
     5161 gaagcatcgt cactcctccg ataaagaaga aaaggaccgt ttggacaagg acatataacg
     5221 actcaagtcc caatactgaa ggagtcaaaa actggttatg cgtaattgtc tgaaagctga
     5281 ttgtggcact gctgacagct agcgagacaa ggataaatgc aaaaattttc ttactcctca
     5341 atgcacatgc aaaatgccag tttccatatg tatggatcgt caagtacatt cctgtaacaa
     5401 ataaaacaag aacaagcata ccaataaaaa tagatggctt ttttttaagc atatcgtcgt
     5461 ccccttatca gaagataaag gaagatagcc ccaccgatga ttccaacgat cacactgact
     5521 ggtatttcat aaggaaaaat caacacgcga gcgacaagat cgcaaaatac taagaacaaa
     5581 ctacctgcta aagcagttac gccaattgtt ttgtgcactt gatctccata tattctagag
     5641 acaagattcg gaatgatcac tccgataaaa ggaatgcttc ctaccatgat caacatgact
     5701 gcactagcca atgatactaa gccaatgcct aaaaactgca tcttctggta atctattccc
     5761 agatttactg caaacgattc gcccagacca atgatcgtaa atcggtaagc aaatagccaa
     5821 accaagagca acaatggaac aacagcatac aataactcat aatttcctcg tatcacagtc
     5881 gcaaaattcc cttgaagcca tgaagtcata ttttgtacca actggaattg ataagcaaaa
     5941 aaagtagcaa ctgaaccaat gatattccct aacatgactc caatcaacgg aagcatcaat
     6001 tgatttttct ggaggaacaa tcgcgtaagg gataaaaaaa gcaatgttcc tgcaaaagca
     6061 aagcaaaatg ctgtcaagga tcggacaatc aaggatgcac caggtaggaa aatcatagcc
     6121 actaaaatac ctaaacgcgc actatccatc gtgcccgcag tcgttggtga aacaaattta
     6181 ttttgggtca aatgttgcat gatcaaccca caaatactac tggtcgctcc cacaaggatc
     6241 aaacaaatcg ttcgtggcaa acgagtcact agcaagattt gtaagctttg cccatctaac
     6301 tggagcagtt ctgacaattg tacattcgat actccgatga acaatgaaat actacttaaa
     6361 ataactaata atgctactag tcgtccgtag cgcatccaat ccacctttct aattgagaat
     6421 gattttcatt cttattttaa gtgaatcgtt gaacaaaagc aaccgctttt tcatatgttt
     6481 taggtattat tgggaatatg ctataatcgt aagaaagaca aagagaagaa ggagggtatt
     6541 ttttatggca caagatgatg taaaaagcca tttggataag ggactttatg gtacaccttt
     6601 agtgaaccct gaagaacagc ataaatattt agggacattc agggaacgct gctatcttag
     6661 tatgactgtt gctgaaatga tccaaccaaa aaacaaagaa aactttttaa aagaactcaa
     6721 aaaacatcca gatgcttcca tactcttgaa tggggctcta cccctttctg tccaaaacca
     6781 atatatccag ctagcaacga aaaacaatag ccgtttcact gtagtcaacg attacgtcac
     6841 tgcaaatcct gaggaattcg gattgctctt aacagcaaaa gaagcagtaa atgaacctgt
     6901 gattgatatc gaaaaaaaat acccagaaga aaactcttcg ccagctgaaa aagaaaaacc
     6961 aaaaaagaaa aaaagcttct gggatcgttt attttaaaac gaaaaaacac ataaattttt
     7021 acatgcaaaa aaagcttttg atcagattga catcaaatag gacaatctgt caaaagcttt
     7081 ttcttttaaa atacttcagg atataacaat ttcaatacat tcatcgtcaa tcttctgcct
     7141 tttcctgcaa aaggataaac atgcatatgc atggctggat tgaaatttgc ttcgatgatc
     7201 ccatatgctt ttttatcagt tgtaggatcg atttctttat ctggtataat caaatcgata
     7261 ccactaatct tagctcctag tgcttctacc gcagaaacgg cgattttttt gtaagcttca
     7321 gaaaattcat cagtcatatc gatcgaatca ccacctgtac tgatatttga gttctccctt
     7381 agataaacaa tttgattggc ttggggaact gattcgatcg tcaacccttg ttctttcaac
     7441 atcaattgtt ctaattcacc taattggatc aattctaaag gtgcacgatg attcgttcca
     7501 cgcaaagggt cactattttt ttcttcaaca agttctttca ctgttcggat actgtcacca
     7561 ataacattag cagggactcg caacatgatg gcttggactt ctccgtcgat cacaaagaaa
     7621 cgatattccg ttcccggcat aaattcttct actaaaaccg aactgtcttc acgaaaagca
     7681 atggctaaac ctgcttgata atcttccaga ctagctcctt ccttgaaaat cgtgatacct
     7741 aacccgtaat tggttgattt aggtttgatc acaaatgcct gctcggcaaa tctcggataa
     7801 gcttttaccg cttcttccat ggatgaaaat tctgcgcctc ctggtacccg gaacccagct
     7861 tcttttaaga cttttttcgt tactgttttg ttttccatga taagtgggac gatatagctg
     7921 tccttacttg tcatgtttgc atttttcaca tattctacat ggtcttggaa ttgcagacgc
     7981 aaaaattgat ccgactcatc taatactttg acttggacac ctttttggat ggcatcgaac
     8041 ataaatatct gagtagaaag ttccatttcg cgaaaaccgg ccaactgata gggacgttca
     8101 tggctttctt tataatattg atgtcccaat gccacagcaa cttcttgctg actcgatagc
     8161 tgtgcttctt gatagagttt cgctgctaac gtttgttcag gatgatccat ttgagtcaat
     8221 gcttcctcta ctaaataaag agaatccaac caatccaatt caaccagcat ttgcttcatt
     8281 ccttcaagaa tttctctacc ttcttgatga aattctgttt gatctgatgg ttgttctagt
     8341 gctactttgt tatttcgagt cgtaccttct gctacccatt ggtcacagtc ttctttttct
     8401 tctgtccata acatgtacat caggaataat tgtaagaacc gaacttgctc tggattgata
     8461 cccaatcttg cataaggatt caaatcgata ttccgcaatt caatataacg aacacctgtt
     8521 gttgctaaat ctgcgacttt ctttccgcct cggaaacgaa gcggtgtata aaattctttc
     8581 tcctccgaaa gtttcccttc ttcgatcatt cgctcgatat ctgctaaata ctgtttcata
     8641 gaagcatagg aaactttcac atttggatga ttcgtatagc ccagcgcact gttgcgaata
     8701 ctgcgaacag gttcttgcgg atgtgattca tctaaaaagt agttcttctc actcattggt
     8761 gaagcaccga ataaataagt gatcatccag cgatagcgca taaagtttct cgctgttttc
     8821 aaataaagtt ctgttttgaa ttcggaaaaa tcttgaaatt cttcctgatg gctgaacaat
     8881 gttcttagca actcatcgcc aaattcaaaa ttgaaatgaa taccgcttac catctgtttt
     8941 cgcttcccgt atttttttgc taaataacgt cgatacaaga catcttcgaa attttttaat
     9001 tttgcaataa tgatctcttc gtctttttcc ggtaaggcag gtggcatact taatggccag
     9061 atcatctctt ctttcggtat agaacgagca gtcacatcat aaacagcagc gagatactga
     9121 aataattcgg gaatagaatc ggtaacaggg gtgatcatct ctgtttgtgt ttcgctaaaa
     9181 tctgtttgga tataggggtg ataggatcga tcgccaaaga ttgctggatg atcggttttt
     9241 gctagatttc ctgcaagatc aacccgctgt ccttcccgtt ctataccaaa tcgagcttgg
     9301 tcgataaaag ggcgcgcatt gacatgcaat aataattgct taaaattcat cattaagtga
     9361 cctccaattc atatgaatct aattataatc aaaaagtcta agaaaaagaa cgaaattgtt
     9421 tgagaaccgc ttacaaataa gtataaaaat gaaggcatca aaaacacagc tatgttaaaa
     9481 acaatcattc aaacaaggag ctgcaacttt tgtcacagct cctgcttttt agacatgggt
     9541 tattcttctt ttagtaatcc tttgaacaat ccaacgacaa aatcatttgg atcaaacggc
     9601 tccaagtcat cgattccttc accaagaccg accaatttca ctggtaaatg caattcatta
     9661 cggatagcaa gtacgatacc gccctttgct gtaccatcta attttgtcaa aacaagaccg
     9721 gtcacatctg ttgtttcttt gaattgtttt gcttgaacca tcgcgttttg accagtggtt
     9781 gcatctaata caagaagtgt ttcttggggt gcttctggta attcccgctg gattactcgt
     9841 tttatttttt ctaattcgtt catcaagttc actttatttt gcagtcggcc tgcagtatca
     9901 actagtaaaa catctgcctg ctctgtcttt gctctttcca aagcatcgaa tacgacagct
     9961 gctggatcgc ctcctgcatt gccacgaaca acttcaacac cagcgcgttc gccccagaca
    10021 actaactggt cgattgctcc agcgcggaag gtatctgctg ctgccatcaa tactttttta
    10081 ccttcgtttt tgaactgatg ggcaagttta ccaatacttg ttgttttccc tacaccatta
    10141 acaccgacaa acaaaataac tgttagtccg tcttcttgga tatttagttc atttacttca
    10201 ttgattcctt ccgcttcata gagatccaca agtttctcga tgatcgcatt ttggacttct
    10261 gccgattttt tcgcatttct gagtttcact tcttgacgta atgcttcggt gattcgtatc
    10321 gctgtttcaa aacctacatc tgcaccgata agtgtttctt ctaattcttc aaaaaagtct
    10381 tcatcgactg ttcgaaaatt ggcaaacaac tcattcatcc gttcaccaaa tgttttacgc
    10441 gtcttttcta aacccttgtc gtacttctcc tgtacttcaa cttcttctgt tttctcttcg
    10501 ccagtaaaag cacgcttgat tttatcaaaa aatcccattt gactccccct actctaatac
    10561 aaatttttgg atcactttgg ctacgccatt ttcttcattg ctggctgtca cgaaatctgc
    10621 tgcttctttg acgaaaggca cagcattctc catcgctacg cctagtccag catattggat
    10681 catcggtaaa tcattttcct catcaccgat cgccatgatt tcttcttgtt tcaaaccaag
    10741 atcttttgcc aataaagaaa taccataagc ttttgtaaca ccttttggca taaattccaa
    10801 aagcatactt cttgttttga tgatctcata catttcatgg aattctgctg gtatttcttt
    10861 gattttagga tctaattctt cttggtcata agcgattact gccttattaa gcacaaattc
    10921 atctgtaata tcgcttatat ccgctggttg gaattgcagc agcttattca acacattgta
    10981 caaggattgc ttccttgggg cactaggcag ctgtaaaacc acattgtcag acaaaacatc
    11041 tagtggcaga tccaattgct gagccagttt gtataagcgt tggatatctg atacttccat
    11101 cactttcttt tccatgattt caccagtatc atttttttgt accaaaccgc cgttgaaagt
    11161 gatgctgtag tcaccttcat ctaccagtcc taattcttgc agataatgcg ccatcgcagc
    11221 taaggggcgt cctgtacata gaacgatctt gaccccttgc tgttttgctt gtgctaatgc
    11281 ttgtttattc tcatctgaaa tcagcttttg ttcatttaat aatgtaccgt ccaaatcgat
    11341 tgctactaat ttgatcattt tcgttcctac actttcgttt cgttgatttt cgcctcttca
    11401 ttgatatctt ccatccgtac agaaacgatt tttgatacac cggattcctg catcgtcact
    11461 ccgtacagta catctgctgc gaccatcgtt cctttgcggt gtgtgactac gataaattgt
    11521 gtgtcatctt ggaaatcgct caagtaacga ccaaaacgtt tcacgttggc ttcatctaac
    11581 gctgcttcta cctcatctaa gatacaaaac ggaacaggac agacacggat aatggaaaag
    11641 agcaacgcga tggctgtaag tgctcgttct cctccagaaa gcaaacttag actttgcagt
    11701 tttttgccag gaggttgtac ttcaatctca atacctgttt tcagcaaatc agttggttcc
    11761 gtcagtacta attcagcttt accgccgcca aacatatttg gaaagacaat tttgaattct
    11821 tgacggatag cttcaaatac ttctttgaat cttgtccgca cttcatcatc catctcatcc
    11881 atcgtttcaa acaattggtt tttcgctgct aacagatcat ctcgctgtgt tgctaagaat
    11941 gtatgtcttt cactgacttg ttcgtattgt tcgattgaat ttaagtttac tggtcccagt
    12001 ttttcaatct gttcttttaa ggatgaaacc tttgttctac tgtcttcgat atcggttgtt
    12061 tcttgatagt cttgggaagc tttctcaaat gtcagctgat attctgactg cagataggtc
    12121 aaatgattat ctaaaatcat ttcagctcgg tctttttgga cttctaattt ggattgttcc
    12181 gacagtcgtg ctttttgctc acgattacgc tctgccaaga ctgcttcaag cttatcgatc
    12241 tccttttgcc ttctatctcg ctgctctttg gcttttgcca actcggcttt taatgtttct
    12301 cgctgagcag ataattcgtt aatttgtttt tccaaacttt cttctgtgac ttcatgatca
    12361 gaaaagtctg ctgtcaatgt cgccaactgc ttttctatcg cttcttgacg ttcggttgcc
    12421 tctgcttttt ggactcgggc accgcggagc tggatctgca gatgattaaa ctgctctttc
    12481 aagacagcaa gatctgcttg ttcttgtgct ttttgacttt gtacttgtgc tcttctggct
    12541 tccatctggt cgctttcttg acttaacgat ttgatttctt cgtcgatttt ttgtcgttgc
    12601 gattcaagat ctgtttgttt gtctttcaat tcgttcgttt gcttttcgta atcttcgata
    12661 aactgctgca gttcacgtgt ctcaaaagtt gagatttgct tttctttttc aaaacgttca
    12721 agttcattta tgatgttttg tagctgattt gtcgcttctt gttcttcaaa acgtaattgt
    12781 tcgcctcgtg tacgcaaaac ttcttgttct tcggctaaac gagctgtttc ttgttgcagc
    12841 tcctgaactt ttttttcttg tgcttggagt tgtttatctg cttcttcaaa ttcactagtc
    12901 aactgtttca attcttgatt ttgtacaaac aaactgcctt ggtttcctcg tttattcgct
    12961 ccacctgtca tggatcctcc ggcattcatc acatcacctt ctaaggaaac cactcgatat
    13021 tgatagcgga tcgtttgcgc gattgcattg gcactagtta agtctttggc taaaaggatc
    13081 gttcctagca ggttttgaac cacagtttgg atttgatcgg gataactgac ttgttcactg
    13141 gcaatcccta taaacccttc tacagctgct gcttgtgtca atatatgagc cggtaattgt
    13201 cttggtttga ttgtcgtcag tggaaggaat gttgctcttc ctcctctttg ctgtttcaaa
    13261 tacgtgatgg cttgccgagc atctttttca ttttcaacga tgacatgctg ggctgcccca
    13321 cctaaagctg cttcgatagc taacgtgaaa tctgcaggaa catcgatcag ttcagccact
    13381 gctccgacaa tacccgaaag ctgctgttta tgctgcaaga ccaatcgaac cccttggtaa
    13441 aaaccaaaat agttttcttg gatttcttga aggcttttct tacgagcacg tagctgctgg
    13501 acttgattca ttaattgata cattttaggc tgttcttttg ctaatgcttc ttggaacttt
    13561 ttcccgtttt gttggatcat ttctaacttc tcttttgttt cagttaaaga tgattttagc
    13621 tgcgcctgct tttgtgtcaa ttcttctttt tgtaagatca atcggtctac tgatgcttct
    13681 acttccgatt gcttggctaa cgtctgcttg ctttttgctg tttcttgtat atattgacgt
    13741 tctagatact tcagttcgtt tcctacagct gcttgttctt gcatcaaatc aacatattga
    13801 tctcttaatt ctgccaataa ttctttcgtt gatttttggt atttttctaa ttcttgctgt
    13861 gtttttatga gatttgcttc agctttttgg atctctgttt ctttttctgc tgctgctttc
    13921 atcaagcttt cttgaagctt ttcaaaatgt ttaacctttt tttgtgcttc tgctaatgaa
    13981 gtttgatatt cttgcgagct tttttgtgta tgctttgtcc gctcctgcaa aacatctttt
    14041 tgtccttctg tctgcttcag tttttccgaa agatctaata atacttgctg atttttttcg
    14101 atcagacgat cggcttgcgc attttcttta cgctgcttcg ccaaaatgga ttcttgttct
    14161 tggatcgact cagatagttt gcctaattct agattgaatt tcgcaagctg tgcttgtttg
    14221 ttgtcccaat ctttttttgc tgtcttgatt tcagcaacca tcaaagagac atcggtttga
    14281 gtcagtgttt cttttagccg taaaaactcc tttgctgcct cactctgggc ggccaaagga
    14341 gttaactgtt cttccaattc gtggatgatg tcttggacgc ggctgaggtt gtcttctgtt
    14401 tcaaaaagct tctgttctgc tttctttttc cgctgcttgt atttcaagac accagctgct
    14461 tcttcaaaga tcccacgacg gtcttccggt ttactactga aaatcgcttc tacttttcct
    14521 tgagaaatga ttgagaacga ttcttttcct aatccagaat ctaagaacaa ttcttggata
    14581 tcttttaatc tgcagctttg tttattgatg aaaaactcgc tttccccagt ccgtcgataa
    14641 cggcgggtta cactgatctc attgtactcc aatggcagat aatgatcact attgtctaaa
    14701 atcactgtga cttctgcaat attcagctgc ttacgggtat cggaaccggc aaagatgata
    14761 tccggcattt ttccgcctcg cagactttta gcagattgtt ctcctaatac ccagcggata
    14821 gcctctgtaa tattgctttt tccgctgcca tttggtccaa ccactgctgt gacgctattt
    14881 tcaaaatcaa tgactgtctt gtctgcaaat gatttaaaac cggctatttc aattcgtttc
    14941 aaatacaaag ctttccctca cttactttta cagtgctgcc aatgcatttt ccgccgcagc
    15001 ttgttctgct aattttttcg atttcccttg tccagtgcca atcaattgat catctacata
    15061 aacttcgatc caaaatactc gttcatgagc tggaccttct tcattgatca atcggtattc
    15121 gattgataca tcacctgatt tttgcaagac ttcttgtagt tttgttttat gatccatctc
    15181 atgtgaaaaa gcacctgctt tgactttagg aaaaatcact ttttcgatga atgcatgggt
    15241 cgtgtcgaat ccctggtcaa gatataacgc gcctaaaaaa gcttcgaata ggtcgcaaag
    15301 caatgctggt cgcgtacgtc ctcctgaatt ctcttctccc ttgcccaaca aaacatattg
    15361 atcaaagtga cattctttgg caaatttcga caagctgtct tcgcgaacga tcgcagctcg
    15421 tgtttttgtc aattttcctt ctggcaaatg aggatataaa cggaataaat actgagaaac
    15481 catcagttct aaaacggcat ctcctaaaaa ttcaagtcgc tcattatccg ataattgcag
    15541 attgcgatgc tcattcacat aggatgaatg ggtaaaagct tgttcaagca aatttagatc
    15601 gtgaaaaacg atgttatagt tttcttttag ttcttttgtc agctggttgt ccattttcca
    15661 cattcctttt atggatattt tttcgatact tccttattat actggttttt tgtcaaattt
    15721 gaaatggttc ggtcaaaagg taagtaaagc tttaataatc ctagtgattg acgagaagtt
    15781 gtgaaaaatt cgtttagttt cgagtatgaa gaaaaaattt tgtgaaaatg gctttccata
    15841 tttttgcata aatttgactt aataccgaga aactggactt tgaacaccgt ttattggaga
    15901 agtcatgaaa tcagcgcctt gacctgaata ttagagaaat aaacagaaaa atatcaaaaa
    15961 accgaaaaag gacatcgccc tttttcggtc atttttagtg attatgaacg tgaatctgct
    16021 gtaacagaaa catttgccca tgggtttggt acatcataag accaatccca gtctttgaca
    16081 cggtcgttga ctggcaatac ttcattacgg aacaacgttg gaatcgcaaa tgcttcttca
    16141 aatgcatatt gttgccattt ttgatatgct tctttttggt actcttcatc aaatgctttg
    16201 cttgaactga tatcgttgat caattttgta ttttcttctg attcataacg agtgtagttg
    16261 aacgcagcat ttggtcccca tagtccactt ggatttggat cagttcctgt attccaagca
    16321 gcttggtaaa catcaatttc aggatcatcg ttttctaatt tatcatagaa agaattgaat
    16381 tcgatcagac gacctgttgt gtattggaca tccaaaccaa tttctttcca ttgttggata
    16441 tagtaatctg ccaatggttg cgctgtttcc ccaccggaca tcgaagcaaa gttgattgtt
    16501 agtttatttc catctttgtc ttctcttaaa ccatcgtcat ccacatcttt gtagccagca
    16561 tcatctaata gttttttcgc tttgtctaga tcttgtgtga atcctttcat ctcatcatca
    16621 tggtatgact ggaatactgg aggaatcaat gaagtcgcat tgcttctcaa acctgcatag
    16681 aaacgttcac ctactgcatt attatctaat gcatagccca ttgcttgacg taatgattta
    16741 tcagccattt ttgaatctgg attgtattcc acactctttg tatctgcatt ccatttacct
    16801 aacttgaatc ctagataagt ataagaagtt tgttcacggc ctaagtttgt atagccagca
    16861 atttctttat aggtatcgta agtatctgtt ggcatttgga aaatcatatc atataattta
    16921 gagttcaatg cttcagttgc acttgccatc ggtacagatt tcatcgtgat ctttttcaat
    16981 ttaggcgtac cattccagta gtgctcgttt ggcaagtatt ctactgattc tcctgcaacg
    17041 atattactca tgtaataagg gccaaaagtc actggatttt tacgtacttg atcgcttgat
    17101 tccatatctt tgattgctac accttctaac gtatgttttg gtgctgcata tgaccagata
    17161 ccaccacccg attgaagcat gcttgggttt acttctttat attcgatttc aactgttttg
    17221 tcgtctattt ttttgattcc ggagattgtg tcggcacttc catcatgata ttcttccata
    17281 cctacgatgt tacggaaagt gtcgtcataa cggataccag tgtaatcttt attcccaatg
    17341 atttcgtaag ggaaaatcac atcgtccgcc gttacatctt caccatctga ccatttgacg
    17401 ttgtctttta ctttgattgt cgcttttttc gtatcttcat ctagatcaag cgttgcagct
    17461 ccgtcgtctg tgattctgaa atcgtcatcg tttgcaaata gcggttcatg agaaggagcc
    17521 ataaaagctg catcatatga atcttggtaa aactcccact ggaacaatcc tttaaactga
    17581 ctgtccgttg cgaccgcagc ttctaattcg ccgtcttcga ttgcatcatc attatttttt
    17641 gttgcaattg gaaaagttaa ttcctctttg ttattgccgt tgcctccaga gttgtttcca
    17701 gaggtatctg tacctccgcc cccgcatgct gcaagaacga cagcagacat cagcgctgca
    17761 aatccaaaaa tcgttttctt cattcctatt tcccccttcg cttctatact agcctaaccg
    17821 ttggcgcgca tctgcagaac gcttgaatgc ttgtccaaca taattgatac tcaacatcaa
    17881 aactaaaata aggattgatg cgggtaacca gatccattgc cgattcacta agacttctcc
    17941 gttacttgca taaccgatca atgtacctaa actaggtaca tttgccggca agccgaaacc
    18001 taagaaagtc aaagttgtct cgataccgat gtttgccgca aagttcatcg tcaaattagt
    18061 aatgattaat gaacttagat tcggcatgat ttcgcggaac atgattttaa aatcattggt
    18121 tcccattgtt tttgaggcac tgacataatc tcttcttgct tcagataatg tcttgcttcg
    18181 gaataatcgg gctttagcta cccaataaaa tgcactcatg atgaatataa aggaccagac
    18241 attgtatctg gaaataatcg atacgaagac gataatgatc agcatgatcg gtagaatcat
    18301 gataaaatca acgatccgca tcaagatgtt gtcaatgatc cctccgtagt agccagagat
    18361 gatccctaat ccaaccccga tgatcgaagt aaggatcgtg atcgcaaatc cgatcgtaac
    18421 agagtttcta gcacctatga tcaattgtcc taatacatca cgtccgcctt catctgctcc
    18481 cagaatgaac ttttgtcctt gtgtcgaaac tgttcctggt gcagcgtatt tgtcgaagat
    18541 actaacatac atcactttgt cttgatcggt cagcatcgca ccgataaaga tcactaataa
    18601 taaaaccact agcaaaccta atgaaaaaat agcaatttta tcttttttaa attctcgagc
    18661 aatcattcgt atccccatag gaggaatact ttcttgaact gctgtattgt ttttttcact
    18721 catcgatcca ttctcctttc tgattggttt tattgaatcc gaatacgcgg gtcaacgata
    18781 ctcatgatga tatctgaaag taatgtcccc actagcgtcg cgattcctaa aatcaatact
    18841 aaggatgtga tcacggtata gtcccgttgg ccgatggaat caataaatag ttttccgact
    18901 cccggataac caaaaatctt ttcgataact acagaaccag caatcaacga agtgatttca
    18961 taccccattt gagaagccat cggcaacgct gcatttcgga aaatatgtcg actgaatact
    19021 ttattcgtcg gtaccccttt ggaacgggct gttctgacaa aatcgagcga tttcgaatcg
    19081 attacttcac ttcgcagata ttggattgtg acggcagtcg ccaaaaatgc ttgggtaatt
    19141 gatggtaaca gaatatattt caaacggtct atccattgag tgataaatcc accttgcaaa
    19201 cctagtgttt gtgatccact tgttgggaac cagcctaaac gataaccaaa aacaaatagc
    19261 atgatcaagc cgaagataaa taaaggaaca gcaaaactaa agaagttgta gattacgaca
    19321 atcttatcca agattgaatt ttgataccgg ccagcaagca tccccagagg cacagcaatc
    19381 aaataagtaa ggacaactgt caagatcgat agatataaag tgttgatgat ccgttcgccg
    19441 atcaagtcag caacagagcg tttgtataag aaactttgac caaaatcgcc ttgcaaagca
    19501 tttccgatcc aacggaagta ctggacatac catgggtcat tcaagccagc tgcttgtcgc
    19561 atctgttcga tcactgccgg atcctgattt ggattgatca aaccggtaaa tggatccccc
    19621 ggcatcgctt gggctaataa gaagatcaga acacttaaaa taataacttg cgggatcatc
    19681 aataaaacac gtcgcagaat cgttttccac attagcttgc acctccatct ttcaacgcca
    19741 ctttgtgtgt agttgtgatc gtacgcaaat cgtagactcg accagtcgca tcatagtatt
    19801 ctttttggtt ttggatatac tcttgttcta ctcttcgtcg attttctttg tggctttccc
    19861 tattttctac atcgatttgc ggaatagctg aaagcagacg tttcgtatag atatgtcgcg
    19921 ggtcattata aatgtcttct cttgtaccga tttctacaaa tcgacctttg tacataattg
    19981 cgatattgtc gcacatgtgt tttactacac ctaaatcatg tgaaatgaat aaatagctga
    20041 ggccgtattc ttgctggatt cgtttcatga aattcaatac ttgcgcttga acagatagat
    20101 ccagagcaga tacaggttca tcggctacga tcagttttgg attggtagca acagcacggg
    20161 ctactcctag acgttgacgt tgtccgcctg aaaattcatg aggatattta tatagcgcat
    20221 cttccggcat cccaacgata tctagcagtc cttttacctt tttcttttct tcttgatcgc
    20281 ttaaccgttc aaaatttcgg atgggttcag caatgatatc caacactcgc tttttaggat
    20341 tcaaactgga cattgaatct tggaagatca tctgcacatc cttgttataa cccatttttt
    20401 tgcggttgct tcgcttcgtt acatcttttc cttcatacat gatttgtccg gctgttacct
    20461 tttctaatcc cacaacggct tttcccgtag tagattttcc agagccagac tctcccacta
    20521 aaccatatgt ctttcctttt tcgataataa aatccacacc atctacagca tatacatgat
    20581 ccgttactcg attgaagaat ccactgcgaa tagggtaatg aactttcagg tctttgattg
    20641 tgattaattc tgtcatctac acctctcctt tttcgtctct aaagtggaaa tgcttatagc
    20701 aggagcaacg taccaagtgg ttcggtgcga cttcatgaag gataggctct tcttcatgat
    20761 cgcttgctgg tatccatgga atacgtggtg caaaccgaca acctttacga ggcatgtttt
    20821 tcagagaagg aacgacacct tcgatcacat ggagttctgc atcatgattt ccttcttgtg
    20881 gtatagagtt cagtaaagag cgtgtataag gatgcttagg atgatcaaac agttctttta
    20941 cacctgctac ttcaacgaac tgtccgccat acatcactgc cactcgatca gccatttctg
    21001 ctacgactcc taagtcatga gtgatcaaga tgatccctgt ttttgtttct tcctgaaggt
    21061 ctttcagtaa atcaagaatc tgtgcttgga tggttacatc tagggctgtc gtcggttcat
    21121 ctgcaatgac gattggaggt ttgcaggcga ttgcgattgc gatgatgaca cgttgtctca
    21181 taccgcctga tagttcatgg ggatattggc gtccaactct cgcaggatta ggaatcccta
    21241 cttgttctag caattctagt gcacgagctt gacgctgttc tgcattcatc tttgtgtgat
    21301 aggaaagtcc ttctttgatc tggtcttcga ttctcatgag aggatttaat gcagacaacg
    21361 gatcttggaa aatcattccg atatcatttc cgcggatttt attatagagc gtttcgttca
    21421 ggtcgattaa attcagatcg ttatataaaa tctcacctgt aatttttgtg ttattaggat
    21481 caagtaatcc cataatcgta gtagccaagg tacttttccc gcacccagat tccccaacga
    21541 ttgctaaaat ctcgtttttg tctaaagtaa atgaaacgtc atctactgca tcgtaatagt
    21601 catctttgag tcggaatcct gtatgtaggt tctgaacttc taataattgg ttatcggaca
    21661 atcgaatacc cctctctgct tcctaaatgg aagtttttct taataaaaaa ggacattaca
    21721 cagaataaag cgttttataa caaaggttat tcttatcttt gtgtaatgaa ttattaataa
    21781 ttatatagaa aatcgcttta ctttgcaaca taatttctgt ttatcgccag aattatcaga
    21841 aaaatgactt ttacgtgtca aaaagattaa aaaaagaagg ataaaaagct gtatgcagct
    21901 ttttatcctt ctttgctttt atttgaaatt atttaagatg gctgctgata taatctactg
    21961 cgccaccgac tgtttcaatt tgttcagcgt cttcatctga aatttccgta ccgaattcat
    22021 cttcaagctc taaaacgaat tccataatac taattgaatc agcttttaaa tcatctttga
    22081 tgttcaattc atccgtcact ttatcggtat ctatctcaaa atgatttgaa ataattttcg
    22141 ctactttgtt aaatacttct tcgcgagtca actttttcac ctccaagaat catacacttg
    22201 tcaattacct acaccatggc taattttact ggcatttttc aggaatgtcc accttttttt
    22261 caatggaacg gattgcttca gatatccaaa tactattctt cgcttttttc aaattgttcg
    22321 actaattgtc caactacatc tgtctcaagc attgtgtgga tttggcggat cgtatagcga
    22381 acagcatcgg ggcctgttgc tccatgagtt ttaatgactg gtgctttcaa gccaaacaaa
    22441 acggcaccgc catgtttgga ataatccatt tctgctttca aagaacgtaa gccgtctttt
    22501 aaaagcatag cgcccatttt tcctttgatc ccttcattta gaatagcaga ttttaataga
    22561 ttcatcatat tcattgctgt tccttcaata gatttcaaaa cagcgttgcc tgtaaatcca
    22621 tctgtgacca ctacatcagc cacaccattg agtagctcac gagcttctac gtttccaata
    22681 aaattcaagc ttgtttcatt ctgaaggagt tcataggctt ttttcgtcac ttcactacct
    22741 tttgttgctt ctgttccgtt gtttaagagt gcgacacgag gacgtccgat acctcggact
    22801 ttacgtgcat aaaaagaacc taaaataccg tattgcaaca aatgttctgg tttgttttct
    22861 gcgttagcgc caagatccag catatcgaaa ccggcacctt ctttccctac tactggcaag
    22921 gtagacatca agccagggcg ttcgatattt ttgatacgtc ctacgatgaa caaccctgct
    22981 gctagtagcg cgcctgtatt ccctgctgaa aatacagcat ctgcttcacc gtttttcact
    23041 gcttgtgcag caaggaccat tgatgcagtc ttttttcgtc gaattgcttt tactggctca
    23101 tcatcactat tgattttttc gtctgtatgg ataatcgtga tgtttttttc atttgttaag
    23161 tatttcttga tttctgcttc ttttccgtaa agtaagaatt ctacttctgg aaaatcttgc
    23221 tgcgctaaag ccacgccttc tacaattgct tgaggtgcgt gatctccgcc cattgcatct
    23281 acggcaattt tcattgtttc cactcctttt tccgtcatca gtataaagta tagcacagtc
    23341 tgctaatcga aataacgatt atcctgattt tctatttgga ggctttgcgc taaaggctga
    23401 tactcaggaa gcatctgcca atcctttatc tgccaaaggg ctgcagcctc ttctctggct
    23461 acctccaaaa catttccatc cgtcaccaag tcagcaatcg caaattgagg cagaccagat
    23521 tgacggaagc caaatacttc accaggacca cgtaattcca gatctttttc gcttagtaca
    23581 aaaccattgg tggtctctgt catgattttc atccgttcca cacctagttc atttttagga
    23641 ttagcaacta agatacagta ggaagcatca cttccgcgtc caacacgtcc acgaagttga
    23701 tgcagctgtg ccaatccaaa tcgatccgca tccatgatca gcatgacggt cgcgttcggc
    23761 acgtttaccc ctacttcaat tacagtagtc gaaactaata tctgcatctg gttgtctttg
    23821 aaggcttcca tgattacttc tttttcctga ttcttcattt taccatgtaa caagccaact
    23881 tcatattttg gtgcaaatag ttcacgaagt ttttcataga tttccactgc attttttaca
    23941 tctaatgctt ctgattcttc aatcagcgga cagatgacat acatttgatg tcctcttgcc
    24001 agttcttttt tcgtccaatc cagtacactg tccaattgag gtgttcttac ccagcgtgtt
    24061 tcgatcggga tacgtccagc tggaagttca tcaatgatag atacatccat ctcaccatat
    24121 gctgtaatag ctaatgttct aggaatcgga gtcgctgtca taaataagac atctggtcgc
    24181 cagccttttt cacgaagtac tttccgctgg ttcacgccaa aacggtgctg ctcatccgta
    24241 ataactagac ctaaattctg aaattcgact ccatcttgga tcaatgcatg tgtgccgatc
    24301 acgatgttaa tttccccttg ctctagtttt tcaaggagct cacgacgttc ttttgctttc
    24361 gttgaccccg taagcaatgc gatggttact tcattgggat caaacagctg ttgcaagctt
    24421 tccatatgtt gttgtgccaa gatttctgta ggcaccatca acgcaccttg gaaacctgct
    24481 gtaacggtag cgtataacgc aatcgcggca accactgttt ttccgctacc tacatctccc
    24541 tgcaaaagtc gctgcatatg ctgcggactg cgaagatccc gacagatttc attcgttaca
    24601 cgtttttgtg catttgtcag ttcaaaaggt agcttttgag taaattcttt caatttttgg
    24661 acatcataaa ggatctccaa accattcgtt tctgcttttt ctgctttttt caatccttga
    24721 agacgcattt gaaataaaaa gaactcttca aaaacgacac gtcgtttggc ttgatggttt
    24781 tcttcgtggt cttttggaaa atgcatactt cttacagcag aagctcggtc aagcagtcga
    24841 tatttctcca caaggttgtt tggcagattt tcttcaatca atgtgccgta ttcttgaaac
    24901 ccttttttga ttagatcaac taatgtcgtt tgacgaattg atttgttgac gtgatatatc
    24961 ggcgaaaagt catccattgt ttgagaacct aaaatcttca tcccgttcaa tgctttacgc
    25021 tttgcatccc atttaccgta tacggcgatt tcctccgata aaatgacttt ttcttttaga
    25081 taaggttgat taaaaaaaga aacgttgaac acatcatgtt cttgcatcat acgaaattgc
    25141 aatcggcttt ttttataacc aaatcgattc atcacaggag gcgagactac gattcctttc
    25201 aaagtaacct tttcttgatc ttggatctcg tttagatttc tttcctgaat atcttcgtag
    25261 cggaaaggat aataagtcag taagtcttca atcgtttgga tgcccaagct ggcaagacta
    25321 gctgctcttt tttctccgac tcctgccagc atagtgattg gatcatctaa agaacgcata
    25381 aatttttcct ccctccctta acaaaaaaag gacttggtca gcgatcatac ctgatcacta
    25441 accgaaggcc ttttatgaat gaatactgtg ttagaaagat attctgacac agaaattatt
    25501 cagcagaaaa tagataagga tagacaggct gatctccttg gtggatctcg atttccaaat
    25561 caggatgttt ttctgttagt ttctcagcaa attcatttgc ttgttcaact gttccttcat
    25621 cacctgccaa gatcgttacg atctctgtgt cctcattgat catttgttct agtgtactta
    25681 acgctgttgc tgtgatatct gggttagaga tcaggatttt tccatcgatc atgcccaaaa
    25741 agtctccttc tttgatctct acaccgtcaa ttgaggtatc tctgatcgcg tgagtgactt
    25801 gaccgctcac aacgctagac aacatttctg tcatcgtttc tttgttttct tctaaagaag
    25861 cttgatcatt gaatgaaagc atagctgtca atccttggga aatcgttctt gaaggaacaa
    25921 ctgctactgg gatatctgct acttctgctg cttgatcagc tgccatgaag atgttcttat
    25981 tgtttggcaa gacaatcact ttatctgcgt ttacttcttg aatcgcttta acaatgtctt
    26041 ccgtacttgg attcattgtt tgcccaccac tgataacata attagcgcct aaactttcaa
    26101 acagctcttg gacgccttta ccagcagcga tcgctacgat accatacggg atacgtggtg
    26161 tttctttttt cgcaaactcg ttcacttctt catcgtgttc caaaatcgtc tcatgctgca
    26221 agcgcatgtt gtcgactttg attttgacta atgaaccgaa tttttgtcca taattcaaga
    26281 cttctcctgg gttttctgta tgcacgtgga ctttgatgat ctcgtcatca ttgaccacaa
    26341 gtaaagaatc tcctatacca tctaaatagt tacggaattc ttcgtaatcg aatgtactat
    26401 cgactgtagg tccttctccg atttttacca tgatttctgt acagtaacca aaatggatat
    26461 cttctgtcgc catttgacct tggacactgc gatgatgttc tgcattgacc atatcatcca
    26521 tttctgctgg agaaggttca tatgtttcat ccgcttggaa ttctccattc aatgcactta
    26581 aaaagccctc ataaacaaac agcagtcctt gccctccact gtctacgaca ccgacttctt
    26641 ttaggactgg aagcaagtct ggagttttag ctaaagcacg ctttgcccct tttacaacag
    26701 ctgtcattac ttcaacgaca tcatcagtac tttttgcttt cttttctcca gctttcgctg
    26761 cttctctagc tactgtcaaa atcgttcctt ctactggttt cattactgct ttatacgcag
    26821 tttcaactcc atgagtgaag gctgcagcaa gatcggaagc atttaatgag acaacatctg
    26881 gaatttgctt agaaaatcca cgaaacaatt gagacaaaat aacgccggaa tttccgcgcg
    26941 cacccatcag caatcctttt gaaagcattg ctgctaattc tcctactttt tctgaggttg
    27001 aatctactac tgccttagct ccactagtca tagatagatt catatttgtt cccgtatcgc
    27061 catctggcac agggaataca tttaatgaat tgacgtattc tgcatttact tgcagacgat
    27121 tcgcacctgc ctggaccatt tcctggaact ggcttgcact tatttctgtt acactcacct
    27181 agataatcct ccttcagatc gactgctgag ttaccagcca gtctcctgcc tagtctggca
    27241 gtacacgaac accttgtaca aagacattaa ctgaattggc agttacgcct aataatgcct
    27301 ctagattgta tttcactttt tcttggacgt tgcgggaaac ttcagagatt ttcgtaccat
    27361 agctgataat cgtataaaca tctacagcaa taccattatc ttcttggcgg acaactactc
    27421 ctcttgagta attttcttta cgcaaaatct cagtaatatt atctttaatt tgatttttgc
    27481 tggccattcc tacaacaccg aacacatctg tcgcggcgcc accaacaact gttgcaatta
    27541 catcattggt aatttcaatg gttccagctg acgtttgaat ttttacagcc atgaatgagc
    27601 ctccttaacg ggtaaaaaac tcccattttt cttctatcat attttatcat agcgcaactt
    27661 gaaataaaag gcagttaccc aaagtactca aaaaccttgc aaaatttcag gtataacctt
    27721 gtttaattta caattattct tctcaattgt caattgtatc tatgaaaatg tacttgcaaa
    27781 tttccattct atatgatatg ttagtctggt atgagctgaa ttattctatt gctccaaatc
    27841 aaggcaaagg aggaaattac catggcaaaa gtttgttact ttacaggtcg caagacaaaa
    27901 agtggaaaca accgttcaca cgctatgaac tcaacaaaac gtactgttaa acctaactta
    27961 caaaaagttc gcgttatggt cgacggaaaa cctaaaaaag tttgggtgtc aactcgtgct
    28021 ttgaaatcag gaaaagttga acgcgtttaa ttgaatgata cttggaccgt tcagatagtg
    28081 aacggttttt t
//
LOCUS       DAZKKZ010000036        27828 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.036, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000036 DAZKKZ010000000
VERSION     DAZKKZ010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 27828)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27828)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27828
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.036"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            288..2027
                     /gene="yfcC"
                     /locus_tag="ACG8LA_001669"
     CDS             288..2027
                     /gene="yfcC"
                     /locus_tag="ACG8LA_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HFQ0203971.1"
                     /translation="MKKTNSSGKPKRDFTKLSTPHTYVIIFGVVIFAWILTFVVPAGK
                     FSTQDIEYKDANGETSTRTVLRQDSFRYAYELDKSYVFDQLEELQDHPAEREKLDVPE
                     KGLEKVIADGEKNLTQEKLDEISLTDDVLYDQYGENIYDTSKKLHKTAKIWGTDDFGG
                     FGFLNFVFEGLVSGDKYGSAVGIAALILVVGGAFGIIMRTGAIDAGIYAFISKTKGLE
                     RLALPLLFFAFSFGGATFGMAEEVIPFSMVMVPFVIALGYDSIVAVTVTYVASQVGNA
                     TSWMSPFSVAVAQGIAGIPVLSGATFRLIMWVVVTALAAGYMMIYAEKIRKKPESSLT
                     YKSDDYFRSHIKKTSDENKKFMLGHKLILLEMLVVLVWIVWGVTQKGYYIPEIASQFF
                     VMGLVAGIIAVLFKLDGMKVNDIASSFQSGAADLAGTAIVVGMAKGILLVLGGSDASV
                     PSALNTILHGIGTALTGVPAVIGAWAMYIFQSLFNLVVTSNSGQAALTMPIMAPLADL
                     VGVSRQVAVLAYQLGSGFMDAFTPVSASLIGVLGVARIEWAKWARFQIKMQGFLFVLG
                     TIFIMIAIAIGLQ"
     gene            2184..3368
                     /gene="iadA"
                     /locus_tag="ACG8LA_001670"
     CDS             2184..3368
                     /gene="iadA"
                     /locus_tag="ACG8LA_001670"
                     /EC_number="3.4.19.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008798 - beta-aspartyl-peptidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-aspartyl-peptidase"
                     /protein_id="HFQ0203972.1"
                     /translation="MKIIRQIEVFAPDYLGKMDVLIAGGKILAVEEQLEGGYEGVEVE
                     ELSGEGKVLTPGFIDCHFHILGGGGEGGYQNRTPEVTLSQLTTAGVTTVVGCLGTDGE
                     GRDMTALISKAKGLEAEGISTYVYEGSYRLPVKTVTDSIIKDFLTIDKIIGIGEIAVS
                     DHRSSQPSFEEFARAVADARVGGMLSGKAGIINVHLGGGKRKLELLTRIVEETEIPIT
                     QFLPTHANRTPELFEACVAFAKRGGTIDFTASEDPDFWEKTDGEVRFSKALKRLIEED
                     VSLDNFTMTSDGQGSLPYFDENNHFLGLGVGSAKALLVGIKEAVQKESIPLEIALRAI
                     TSNPARILKLDKKGKIEIGADADLCILDKETLDIDTVIAKGEIMVQEKEVKVWGTFEK
                     SF"
     gene            3479..3682
                     /locus_tag="ACG8LA_001671"
     CDS             3479..3682
                     /locus_tag="ACG8LA_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HFQ0203973.1"
                     /translation="MADLKGRSKDMKDKVVGEGKEAYGKATDDKSKETEGKAQSLGAD
                     IKEKARNLGDEVKDKFSRKDEKK"
     gene            complement(3783..4445)
                     /locus_tag="ACG8LA_001672"
     CDS             complement(3783..4445)
                     /locus_tag="ACG8LA_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0203974.1"
                     /translation="MLRTEQLGFWYQDPQDALYKDVELNFEAGKMYAILGASGSGKTT
                     FLSLISGLDAPKEGKVYYQDRSLNKIGLRSYRKNDVSIIFQAYNLLPYLSALDNVIAA
                     MEITKTKQENYRQVALDRLARVGIDEILAKKQVTKLSGGQQQRVAIVRAICCEHQLIV
                     ADEPTGNLDETTSQDIVKLFQEIAHEQNRCIIIVTHEIEVAKSCDEVFELKNKKFQKI
                     EV"
     gene            complement(4458..5960)
                     /locus_tag="ACG8LA_001673"
     CDS             complement(4458..5960)
                     /locus_tag="ACG8LA_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFQ0203975.1"
                     /translation="MNFMKRAWKSTKVKWGRSLLLFAVFTAILIFVLAGLTIRSAAEE
                     AANQAQKEVGATVTLSANREASFKKQEQTSSSGSTTEERPDPGSFSLTPVSLTDAEKI
                     AELDNVKSYSFESSASAMAKDGITAITSSDSSEDSSETTDAGGEPAGGMGGNPQMTQA
                     DFQISGVSATAQNSNFSDGTAKITDGEGIDDSDKGTNNVVIDSTLAETNDLAVGDTFT
                     ITSTEDEDTTYEMTIKGIYESSETSGSMGMKFNFMNPSNTLYTSYTFANELNGTSDDN
                     TIDSAIYTLSDPDKMDEFLKEAEKLIDTDTFSLQSNDSMYQSMLEPLNNVASFSKNVV
                     LLVAVAGIIILTLIIMITIRERRHELGVLLSLGESRSKIILQLFTEVAICMILALGVA
                     SLSGNVVANAVGQQLLDQQTETTTQNQQAPGGGQMPGNRQEQGGQRDGQQGTTNNPFA
                     VSDQVSELEINVKPAQLGLLAGVAFGISLFSVFLASIGILRLNPRKILLN"
     gene            6508..8187
                     /locus_tag="ACG8LA_001674"
     CDS             6508..8187
                     /locus_tag="ACG8LA_001674"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HFQ0203976.1"
                     /translation="MSTIKIIPLGGVRENGKNMYVAEVGEDIFILDCGLKYPENELLG
                     IDVVIPDFTYLEENIDRVAGVFLTHGHADAIGALPYLLSKISVPVFGTELTIELAKLN
                     VSRNEAAKGFKDFHVVDEHTEIDFGETVVSFFRTTHTIPDSVGINLKTKEGSIVYTGD
                     FKFDQTAIPMYQTDYARLAEIGKEGVLALLSESANAENPQPVASEAQIADEVFDTIKY
                     WEGRIIVACVASNLQRVQQVLDAAEKAQRKVVLTGQDFERIIRTAMRLEKLQLPSEDL
                     LVTLKDMKNYDPEELIILETGRMGEPIKSLQKMANGTHRNVKIEEGDLVYITTTPSIA
                     METIVAKTEDIIYRAGGTVKLISENMRVSGHANPNDLQLMINLMKPTYFVPVQGEYRE
                     LAAHADLAHAVGMPYKNIYITGRGDVLEYKNKRMSVAGTTSAENVMIDGLGIGDIGNI
                     VLRDRKILSEDGIFVAVVTISRREKKIISKPQITSRGFVYVKASRDLMKESSNMIETI
                     VEKHLESNDFEWSKLKQDIRDQLGRYLFEQTKRRPVILPVIMEATQRRNKK"
     gene            8314..8793
                     /locus_tag="ACG8LA_001675"
     CDS             8314..8793
                     /locus_tag="ACG8LA_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016829 - lyase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HFQ0203977.1"
                     /translation="MMSQTKVERYLEEQKISYQPLDFSHVVEESFTEELQKRGIDPAL
                     ICKTLVVKGNKTGVIIALIPLNDHLDYKKTRQVTKDRKVGFPGMDFVLMHTGYPHGAN
                     TPIGIKLAHPDYCFLADSSLKEKEEVIVSSGEIGRSLRIKVADLEKIVHPIYADLIS"
     gene            9012..9692
                     /locus_tag="ACG8LA_001676"
     CDS             9012..9692
                     /locus_tag="ACG8LA_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HFQ0203978.1"
                     /translation="MKITYHGHSCLTIEMENGQRVMIDPFITGNPLTDLTAEEVKTDW
                     LLITHGHSDHIGDMIPIAKENQATIISIVEIADYANSRGVDSFGMNIGGKHAFPFGVV
                     KFVHAQHSSSYEVDGIVQYMGEPSGIIIQAEGKTIYHAGDTAYFSDLGLLAEEFDIDV
                     AFLPIGDNYTMGPEDAAKAAQTIRAKKVVPIHYNTFPVIEQDPESFVELLEDSEGKIM
                     SVSETLEV"
     gene            9700..11031
                     /locus_tag="ACG8LA_001677"
     CDS             9700..11031
                     /locus_tag="ACG8LA_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DRTGG domain-containing protein"
                     /protein_id="HFQ0203979.1"
                     /translation="MATKHDLILEYIESLPVGNRISVRSIAKELNVSEGTAYRAIKDA
                     ENVGLVSTIQRVGTIRIERKLKKHIERLTFGEVVRIIEGDVLGGAAGLDKVLNKFVIG
                     AMTKHAMERYITPGSLMIVGNRAEVQKLALEDGAAVLITGGFNTTAEIAKLADDLEMP
                     ILRTSYDTFTVATMINRALSDQLIKKDIMLVSDIYMPAEKTHYLQQTDTISDYQRLSE
                     ETQHSRFPVVNRHHRLMGIVTAKDVLGKSPNQIIDRVMTKEPISVKKTMSIASVSHQM
                     IWDGLEVMPVVSDDLTLEGLITRQDVMKAMQLVQRQPQIADTISDQISGNIHTIDTDR
                     EGNRLENPKFKFVVAPQMVNGVGTISFGVLSEIISDVAQKTMVMNQKRNILIEQVNLH
                     YLRLIQLESELDIRPRVLEIGRRSAKLDIEVFIENTIVSKAIVVCQVMERS"
     gene            11046..12008
                     /locus_tag="ACG8LA_001678"
     CDS             11046..12008
                     /locus_tag="ACG8LA_001678"
                     /EC_number="3.1.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004527 - exonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008441 - 3'(2'),5'-bisphosphate
                     nucleotidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HFQ0203980.1"
                     /translation="MTVQQEIVDTIKKYDKIIIHRHLRPDPDALGSQVGLAELLRESF
                     PEKEIRQVGETIEGLRFLAEMQEVEDVFYQGALVIVTDTANSPRISDQRYQLAEKLIK
                     IDHHPNDDPYGDLVWVNTKASSCSEMIAEFALMFPESLKMNVKAARLLYAGIVGDTGR
                     FLYPSTTSRTLEIASILRNYPFDASALNREIEQMPMKVAKLSGYLYQNIQVDENGAGR
                     IILPQEILDKYGIDDSETASIVSLPGVIDEVLAWGIFVQQPSGYYRVRLRSKGPIINE
                     LAKRHHGGGHPLASGANAKDLAEVEEIYKEIQDICQSYKSRKTE"
     gene            12119..12457
                     /locus_tag="ACG8LA_001679"
     CDS             12119..12457
                     /locus_tag="ACG8LA_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein YjdM"
                     /protein_id="HFQ0203981.1"
                     /translation="MTLPNCPECGSEYTYEDRGLLICPECGNEWNKEEQETVIEDGLV
                     VLDANGNRLLEGDSVTVIKDLKVKGASGAIKQGTKVKNIRLVEGDHNIDCKVEGFGPM
                     KLKSEFVKKN"
     gene            12536..13243
                     /locus_tag="ACG8LA_001680"
     CDS             12536..13243
                     /locus_tag="ACG8LA_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metallopeptidase"
                     /protein_id="HFQ0203982.1"
                     /translation="MYGYGMYGFLDPTFLLVILGLVISGIASAYVNSTFRKYDQVRSK
                     NNVTGTQAAQYILQSQQINNVGVQQIAGDLTDNYNSGNKMLSLSQATAQSTSVAAIGV
                     AAHECGHAVQDASGYVPLKIRAALVPAANFGSMISFPLIMVGVLLSWNSTLINIGIFA
                     FSLALLFQLVTLPVEFNASRRAIQILSEGGLLTEEEVPMARHVLFAAALTYVAAALST
                     FLQLLRLILLFGGNRRD"
     gene            complement(13346..14827)
                     /locus_tag="ACG8LA_001681"
     CDS             complement(13346..14827)
                     /locus_tag="ACG8LA_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0203983.1"
                     /translation="MLIEARKKELLVLQMVIQKNNCSLQELSNDLHIPKRTIKELIRK
                     INVSLKQFLLIDEFIYSNHKGEIQTKETDQTKKLAVFSKLKLCYLKESNRFNYLMLLI
                     NYPQTAVPKKYLLEQLYISPSYLEKLTKQLNHSLKKFHLRILSVKNCCTLEGNELSIR
                     LYLYFFLSDTFGGNDWPFSSLELNALKMNSTDEQIEKISKQEKNIYLLLTLFILRNKQ
                     QAYFPKTSSEITELMDLLQHTHDYSEYFTSFSVSRPCEETETERAYFNYFFYCFFPNQ
                     ISFRQKQEIGFLFSTSKNLICRQVGQLMTYLTQQFPLNHLENKIPIYFYFLVLAVVFF
                     ELLGESSSSFSTLCFPEATSNHSSSFIQEKKLREKIDTIFSKNGERNQISQYLSQLIQ
                     HLLQTETKEQLLIHLQITKQFTGNYHLQSHLQQLFRKDAVKITAYSEHADLIITDQHE
                     KISDETETFYLDTTHNTVLFGKLIKAVHELYMKKGYENKTKRM"
     gene            15136..15672
                     /locus_tag="ACG8LA_001682"
     CDS             15136..15672
                     /locus_tag="ACG8LA_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFQ0203984.1"
                     /translation="MMGRVTNYSKEYLLFKSMVYVEEYGMKSITARELAEFCGCSTYP
                     IYTHFKSISGLKEKILEEITVYFENYLAECSSDDVLSIVYLLKDFFSIHESIREIIAK
                     SDLDMDSLFKRPFFSYVKGHTKIKEEKSLELVWLNALGSLRSDDSSQDFLEMMNAVWD
                     KNEVTDEYLENILKEQSP"
     gene            15750..17120
                     /locus_tag="ACG8LA_001683"
     CDS             15750..17120
                     /locus_tag="ACG8LA_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HFQ0203985.1"
                     /translation="MKEEATTLPQQFIKKYRLLLGEEASDFFSALEQGSVKKGFRWNP
                     LKPAGLDMVQTYHSEELQPAPYSNEGFLGTVNGKSFLHQAGYEYSQEPSAMIVGTAAA
                     AKPGEKVLDLCAAPGGKSTQLAAQMKGKGLLVTNEIFPKRAKILSENIERWGVSNAIV
                     TNHAPAELVPHFSGFFDRIVVDAPCSGEGMFRKDPNAIKEWTEESPLYCQKRQQEILS
                     SAIKMLKNKGQLIYSTCTFAPEENEEIISWLVENYPVTIEEIPLTQSVSSGRSEWGSV
                     AGLEKTIRIWPHKDQGEGHFVAKLTFHGQNQMHKEKKTRKKSKVQMTKEQEKLWTEFS
                     NDFHYEATGRLLVFNDHLWEVPELAPSLDGLKVVRTGLHLGDFKKNRFEPSYALALAT
                     KKIENIPCLPITQKEWQSYTAGETFQRDGNQGWVLLVLDKIPVGFGKQVKGTVKNFFP
                     KGLRFH"
     gene            17187..17522
                     /locus_tag="ACG8LA_001684"
     CDS             17187..17522
                     /locus_tag="ACG8LA_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0203986.1"
                     /translation="MKTSTKVTIGLSVAAAASVATAVVVSGKVMEKIHHMTTRTKVKK
                     FVYDKFDGNEKLLEIVDGLSDSDLDSLMGMLAKIKSGKKKISVYGDSIKDSTEDVKDR
                     LMHFVEKMM"
     gene            complement(17603..18460)
                     /locus_tag="ACG8LA_001685"
     CDS             complement(17603..18460)
                     /locus_tag="ACG8LA_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0203987.1"
                     /translation="MKMDKLLALYPQAQKKNSPASEADILSFAIDDAFIWIKQDSLSQ
                     QETSLLKALFPVINDQKKHPWYHYLFKDASCVQEKSFRLIQLHVESKGEFLKKEWQDT
                     ILELFRYSADFFFYTDTDALLVEQINRDYLDATEINGIFLSLDADFDTTTSVFVGSFH
                     SPGTDLVPLFAEERKIFLTEQNNLYTHSRTFSMQDVALHYYTKDTVKDSKLIKSYIEL
                     IKQNEMEVIIQELWNELGNVSSAAKTLFLHRNTLKYRIEKFQEQSGFNLKKANDLLFC
                     YLLLLHEHN"
     gene            18567..19082
                     /gene="tadA"
                     /locus_tag="ACG8LA_001686"
     CDS             18567..19082
                     /gene="tadA"
                     /locus_tag="ACG8LA_001686"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008251 - tRNA-specific adenosine
                     deaminase activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0002100 - tRNA wobble adenosine to inosine
                     editing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="HFQ0203988.1"
                     /translation="MVNTNLDAVEKEKWMRLALAEAKKAEMLHEVPIGAVVVLDGKVI
                     GRGYNLRETTQDATTHAEMLAIKEACEKVGSWRLEDAALFVTLEPCPMCSGAMILSRV
                     AEVYFGAYDPKGGTAGTLMNLLEDERFNHQAYVEGGILEDECGMILTDFFRKLRQRKK
                     KLKKDWSTNEK"
     gene            19105..19189
                     /gene="ffs"
                     /locus_tag="ACG8LA_001687"
     ncRNA           19105..19189
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="ACG8LA_001687"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            19399..20784
                     /locus_tag="ACG8LA_001688"
     CDS             19399..20784
                     /locus_tag="ACG8LA_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional metallophosphatase/5'-nucleotidase"
                     /protein_id="HFQ0203989.1"
                     /translation="MEKIVILHTNDLHSHLENWPRIRRFLDQRKRENEKKEKTTTIAV
                     DLGDFVDRWHPLSEATNGQENILLMNEVGYDAATIGNNEGVGNSKEELNHLYDHAEFD
                     IILDNLFDKNTLQPPAWTKPYKIITTKHQTKIGLIAFTAPFPLTYNPNGWDIRNPYDI
                     LPELVEDLRSQVDVLVLMSHLGIQDDFQIAKEIPAIDVILGSHTHHLFREGHVINDVQ
                     IAAAGKYGQYVGEVHLTIDEEKKILKHSAKAIPTETMTAFTEDEQEINSYLERGHELL
                     KEKEVADLPFSLSLDIFNEHSFIQVAFEAVKERGKTEAAILNSGLFLTEIPKGRVNQD
                     QLHTALPHPMHLLNVTLGGNDLIRLVLEIEKNRNFLRNYPMKGMGFRGKIFGQMVYNG
                     ITYDSINHQVFWKNKPIDLNKNYTFTTVDHLMFVPFFPTIEIAGKNEFLFPEFIRSVV
                     GDYLKAHYPIK"
     gene            20821..21498
                     /locus_tag="ACG8LA_001689"
     CDS             20821..21498
                     /locus_tag="ACG8LA_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HFQ0203990.1"
                     /translation="MSAKQNEQQNVEHKTEIAKKKSSAEQETTVTEELTAALEEIVEE
                     PKAEKVKGELVTLLDDSNFLIGERHYRLVSDYREGFNAEKLGERYSDVLARYDYIVGD
                     WGYEQLRLKGFFQADNRRAHPDQRIDSLEDYLYEYCNFGCAYFVIERIGGKKEKTTQR
                     RKKKKNHNRAYIDEKKGPVASNRKKPVIKNRKTESAKTSEKVKKQEQPKQVEKTKTAF
                     TIRKREE"
     gene            21506..22270
                     /locus_tag="ACG8LA_001690"
     CDS             21506..22270
                     /locus_tag="ACG8LA_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HFQ0203991.1"
                     /translation="MDYKGYLIDLDGTIYRGTQPIPAGKRFVEELQKRKLPFLFVTNN
                     TTKSPETVANRLADEFDIHVAPETVYTATLATIDFMKADGKGKKVYVIGEAGLIDLIL
                     AAGFTWEEEAPDYVVVGLDNYLTYEKVVKATLAIQKGATFIGTNPDKNIPTERGLLPG
                     AGSVISFVETATQTPPIYIGKPEAIIMDKAVEVLGLQKEEVIMVGDNYETDIQAGIRN
                     NIDTLLVLSGFTKEEDVPGLPIPATYVKQSLDEWSF"
     gene            22272..22931
                     /locus_tag="ACG8LA_001691"
     CDS             22272..22931
                     /locus_tag="ACG8LA_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HFQ0203992.1"
                     /translation="MKNSRWQWMEYAGLFSLFLTLISLAVGVTINFRPLYVFDIGHLQ
                     ILDYTSLDQETLLKNFDHLMNYLNNPFKTILSLPDFPVSASGAHHFYEVKILFLVDYA
                     VFFITLIPSILFIKYLQKNDRLWRLIRPFQIGMLLPVVFGFFMMIGFDRFFILFHETF
                     FNNDDWLFDPVTDPIINVLPEEFFMHSFILFFVLLELFFAVFLFLGKNSLKQTKKKEL
                     V"
     gene            complement(22961..23470)
                     /locus_tag="ACG8LA_001692"
     CDS             complement(22961..23470)
                     /locus_tag="ACG8LA_001692"
                     /EC_number="3.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008962 - phosphatidylglycerophosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0006629 - lipid metabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HFQ0203993.1"
                     /translation="MVVKTETLEEKARELLKERGVTVEDIAQLVMFLQKDYISDLTLA
                     DCTESVNSVLTKREVHNAIITGIQLDILAEKKKLMSPLQHIIEDDEGLYGIDEILALS
                     IVNVYGTIGFTNYGYIDKVKPGILKELNSHDGVHVHTFLDDIVGAIAAAAASRLAHKE
                     PEKRSRLTQ"
     gene            complement(23582..24580)
                     /locus_tag="ACG8LA_001693"
     CDS             complement(23582..24580)
                     /locus_tag="ACG8LA_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HFQ0203994.1"
                     /translation="MEIYDITIIGAGPVGMFAAFYAGMRQAKTKIIDSLPQLGGQLAT
                     LYPEKYIYDIPGYPAIKASELIDQLEKQLTTFNHTFHLKEEVLSLTREDEVIEITTNK
                     GIHYSKAVILALGNGSFQPRKLNLDNAESFENHGLDYFVNDLMKYAGKKVAIAGGGDS
                     AIDWTLMLEPIASEVYLIHRRPEFRAHEHSVSRLKSSSVNLLTPYLIDGLSGNNGELT
                     DIRLKKVKSDETIDLMIDSLIVNYGFSSNLEHLSSWGLDSTRNAITVKSDMSTSIPGV
                     YAAGDICTYEGKVKLIATGLGEAPTAVNNALHYINPKERTQPGHSTSLYDKNLRPS"
     gene            24781..25365
                     /locus_tag="ACG8LA_001694"
     CDS             24781..25365
                     /locus_tag="ACG8LA_001694"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFQ0203995.1"
                     /translation="MAFPQLDLKSEKGPKAVIKTNRGDITVQLFPELAPKTVQNFIEL
                     SKKGYYDGVIFHRVIPDFMIQGGDPTGTGMGGESIYGESFEDEFSRELFNLRGALSMA
                     NSGPNTNGSQFFIVNNTNVPANMLGQLEGAGFPSEIIEAYKGGGTPWLDFRHTVFGHV
                     LEGMDTVDEIANVQRGPQDRPVHDVVIETIEISE"
     gene            complement(25442..26617)
                     /locus_tag="ACG8LA_001695"
     CDS             complement(25442..26617)
                     /locus_tag="ACG8LA_001695"
                     /EC_number="4.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0047804 - cysteine-S-conjugate beta-lyase
                     activity [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MalY/PatB family protein"
                     /protein_id="HFQ0203996.1"
                     /translation="MIEFDKQISRKDTESVKWDAIAETYQMDDLLPLWVADMDFLSPG
                     GVAKAFSEYIKHGIFGYATLSDKLYQAIIHWERQHHAVELTKENIVFTSGVLTSLAAA
                     VQTFTKPGDSILIHDPVYPPFSSIIETNQRHIVRSSLLEKNNHFIMDLSDMEKKIEEN
                     NVKAMILCNPHNPGGRVWSKEELKQLSELCLKHQVILFSDEIHQDLTLFDHTFTSMLT
                     IDPNLDDLLVAFTSATKTFNLAAIKNSMVFIKNPEMKADFEKHLVMNQQHEINTFGLI
                     GTQAAYETGGEWLSQLIPYLEKNVQTVNQFFEQYLPKVRIMNPEGTYLMWLDFTAYIS
                     DDQELENTLVRKGKVVLNPGITFGPSGHGHMRLNIACPEETLLEGLNRIKYALETID"
     gene            26699..27079
                     /locus_tag="ACG8LA_001696"
     CDS             26699..27079
                     /locus_tag="ACG8LA_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvfD/Ygs/GSP13 family RNA-binding
                     post-transcriptional regulator"
                     /protein_id="HFQ0203997.1"
                     /translation="MTYKIGQIIEGKVTGIQPYGAFVSLDNETQGLIHVSEVQSGYTK
                     NIHSLLKVGQPVTVQIIDIDEYSKKISLSLRTLEKTNPAVPYRRKRYFTNKNRKIGFT
                     TIAEQLPIWIEEALSELERKENKK"
     gene            27153..27515
                     /locus_tag="ACG8LA_001697"
     CDS             27153..27515
                     /locus_tag="ACG8LA_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0203998.1"
                     /translation="MASKRVAGTIMLHLEDGTKKFLVHSIDDKLEFALAELSEGKTGL
                     ANILNFLKEIVHIDVSKISLMELTNTHIKEENVPLFVFETEQKNQREELGEGYIWEEP
                     GQMRSVLGTYEVEGVPFF"
BASE COUNT         9067 a         4690 c         5793 g         8278 t
ORIGIN      
        1 tgcaatgaaa ttcaattttt caatgattgt aaaatgaaaa aaacaggacg agattttctc
       61 taatctaaaa ataaaaaaag aattttaagg aaaaacagag aaataaaata cttaatataa
      121 atggaaagag aaaaaaataa tcatacatag gagaaaaaaa acaaaataga aaaaagtgat
      181 tttctaataa attattcatg tggaaatgtc atttttactg tataattcat ttgattatcc
      241 attttttatt catcaaaatt actgaaaaaa gaaaggaaga aataaatttg aagaaaacaa
      301 attcttcagg aaaaccgaaa cgcgacttca ctaaattatc gacaccccat acgtatgtca
      361 ttatttttgg tgtagtcatc tttgcatgga tactgacttt tgtcgttcca gcaggaaagt
      421 tcagcacgca agatattgaa tacaaagatg caaatggcga aacaagtact cgtactgttt
      481 tacgtcaaga ttccttccgt tatgcttacg agctggataa gtcgtatgtg tttgatcaat
      541 tagaagaact gcaagatcat ccagcagaac gtgaaaaact ggatgttccg gaaaaaggat
      601 tggaaaaagt cattgctgac ggagaaaaaa atcttacgca ggaaaaacta gatgaaatct
      661 ccttgacaga tgatgtgctt tacgatcagt acggcgaaaa tatctatgat acttctaaaa
      721 aattgcataa aacagccaaa atatggggaa cagatgattt tggcggcttt ggtttcttaa
      781 attttgtttt tgaaggacta gtatctggag ataagtatgg atctgctgta gggatcgctg
      841 cattgatcct tgttgttgga ggtgcttttg gtattattat gcgtaccgga gcgatcgacg
      901 caggtatcta tgcgtttatc agtaaaacta agggactgga gcgtttagct ttaccgctat
      961 tattctttgc tttttcattc ggtggcgcta cattcgggat ggcagaagag gtaattccat
     1021 tctcaatggt gatggttcca tttgtcattg cgttaggata tgactcgatc gtagcagtaa
     1081 ccgtgactta tgtcgcatct caagtcggaa atgcgacctc ttggatgagc ccgtttagcg
     1141 tagcggtggc tcaagggatt gctggaatcc ccgtgttgtc tggtgcgaca ttccgattga
     1201 ttatgtgggt agttgttact gcattagccg ctggttatat gatgatatat gcagaaaaaa
     1261 tccgtaaaaa accagaaagt tcgttgactt acaaatcaga tgattatttc cgttctcata
     1321 tcaaaaagac atctgatgaa aataaaaaat tcatgcttgg gcataaattg atcttattag
     1381 agatgttagt tgtccttgtc tggatcgttt ggggcgtgac tcaaaaaggc tattacattc
     1441 cagaaatcgc ttctcaattc tttgtgatgg gattagttgc tggaatcatt gctgttcttt
     1501 tcaaattaga tggaatgaaa gtcaatgaca tcgcttcttc tttccaatct ggtgcagctg
     1561 atttagctgg tacagcaatc gtagtaggta tggccaaagg gattcttctt gtcttgggag
     1621 gatctgatgc atctgttcct tcagctttga atacgatttt gcatgggatc gggacggcgt
     1681 tgaccggtgt tccagctgtc attggtgctt gggcgatgta catcttccaa agtttgttca
     1741 acttggttgt tacatcaaat tcaggacaag cagctttgac tatgccaatc atggctccac
     1801 tggcagattt agtaggtgta tccagacaag tagcagttct tgcttatcag cttggttcag
     1861 gttttatgga cgcttttaca cccgtatcag ccagcttgat tggtgtgcta ggtgttgcac
     1921 ggatcgaatg ggcaaaatgg gcaagattcc aaatcaagat gcaaggattc ctgtttgttt
     1981 taggaactat tttcatcatg attgccattg caataggtct gcagtagtac tggagacctg
     2041 taaataaaaa agtaatccaa acagtagata aggactccaa gaaccgtcat tttacggtaa
     2101 aatcaaagga gtaaagatcc tatcgtttgg attatttttt aagatcctat catcagttat
     2161 acttaaagaa agaggaaaaa tgtatgaaaa tcattcgaca aattgaagtg tttgcaccag
     2221 attacttagg aaaaatggat gtactgattg ccggtgggaa gattttggct gtagaagaac
     2281 agctagaagg cggctacgaa ggagtggaag tagaagaact ttcaggtgag ggaaaagtac
     2341 taaccccggg tttcattgac tgtcatttcc atattttagg tggaggagga gaaggcggtt
     2401 atcaaaatcg aacgccagaa gtcacattga gccaattgac tacagctggt gtaacgacag
     2461 ttgtcggttg tttgggaaca gacggagaag gtagagatat gactgcgttg atcagcaaag
     2521 cgaaaggtct ggaagcagaa ggaatctcca cttatgtata cgaaggttcg taccgattgc
     2581 cggtaaaaac agtaacagat tctatcatca aagacttttt gacaattgat aaaattatcg
     2641 gaatcggaga aatcgcagta tccgatcacc gttcttctca gccaagtttt gaagagttcg
     2701 ctcgtgcagt agcagatgct cgtgtaggag gcatgttatc cggaaaagct gggatcatca
     2761 atgtccactt aggcggagga aaaagaaagc tagagctatt gacacgaatc gtagaagaaa
     2821 cagaaattcc gatcacacaa tttttgccta ctcatgcaaa tcgcacacca gaattatttg
     2881 aagcttgcgt ggcatttgcc aaacgtggtg gcacgattga cttcactgct agcgaagatc
     2941 ctgatttttg ggagaagaca gatggtgaag ttcgcttcag caaagcactg aaacgattga
     3001 tcgaggaaga tgtttcttta gataatttca cgatgacctc agatggacaa ggaagcttgc
     3061 cttattttga tgaaaacaat catttcctag ggttaggagt aggaagtgcc aaggcattgc
     3121 tagtagggat caaagaagct gtgcaaaaag aaagtatccc tttggaaatc gccttacgag
     3181 ctataaccag taatccagca cgtatattga aattggataa aaaaggaaaa atcgaaattg
     3241 gtgctgatgc agatctgtgt atcttggata aagaaacgct tgatattgat acagttatcg
     3301 ctaaaggaga aataatggtc caagaaaaag aagtcaaagt atgggggact ttcgaaaaaa
     3361 gtttttaatc aacagctcta actatctttt ttagaaaacg agcgttctgt ttgtctgtat
     3421 ctgttgttga tgttaccctg aaggtagatc aataaacaaa ctaagaggag gaagcacaat
     3481 ggcagattta aaaggacgtt ctaaagatat gaaagataaa gtagtcggtg aaggaaaaga
     3541 agcatacggc aaagcaacag acgacaagag caaagaaaca gaagggaaag cacaatcact
     3601 aggtgctgac atcaaagaaa aagctcgaaa tttaggcgac gaagtcaaag acaagttttc
     3661 tcgaaaagac gaaaaaaaat aaaaaccact tattactaat tgaatcaagc aaataaaaaa
     3721 tccgaaccat atctgcgaga cagatatggt tcggattttt tatttgatca ttatcctgtt
     3781 ttttaaactt cgattttttg aaatttttta ttttttagtt caaagacttc atcacagctt
     3841 tttgctactt caatctcatg agtcacgatg ataatacagc gattttgttc atgggcgatt
     3901 tcttggaaaa gtttgacgat atcttgtgaa gttgtttcat ctagatttcc agtaggctca
     3961 tccgctacga ttagttgatg ttcacagcag atagcacgaa cgatagcgac tcgctgctgc
     4021 tgacctcccg aaagtttggt cacctgtttt tttgctaata tttcatcaat tcctacacga
     4081 gccagtcgat ctaaagcaac ttgtcgataa ttctcttgct tggtcttagt gatttccatt
     4141 gctgctatga cgttgtctag agccgataaa taaggaagca agttgtaagc ttggaaaata
     4201 atcgagacat catttttacg ataacttctt aacccgattt tgttcagtga acgatcttga
     4261 tagtatacct ttccttcttt tggtgcatct agtccagaaa taagcgaaag aaaagtcgtt
     4321 tttccagaac cacttgctcc taaaatagcg tacatttttc cagcttcgaa attcagttct
     4381 acatctttat aaagcgcatc ttgcggatct tgataccaaa atcccaattg ttctgtccgt
     4441 aacatcaaat tcctccttta gtttaatagg atttttcttg ggtttaatct taatatccct
     4501 atagaagcta aaaagacaga aaacagactg attccaaatg ctactccggc taatagtccc
     4561 aattgtgcag gtttgacatt gatttccaat tcgctgactt gatcagaaac agcaaatgga
     4621 ttattcgtgg ttccttgttg accatcgcgt tgaccgcctt gttcttgtct gttacctggc
     4681 atttgtccac cgccaggagc ttgctggttt tgtgtcgtgg tttctgtctg ttggtcaagt
     4741 agctgctgtc ccacggcatt cgcgacgacg tttccgctaa gcgaagcaac tcctaatgca
     4801 agaatcatac aaatagccac ttcggtaaac aattggagaa tgattttact tctggattct
     4861 cctaaagata gcaagacgcc taactcatgc cgacgctccc gaatggtaat cataatgatc
     4921 agagtaagta tgataatacc ggctacagcc actagtaaaa caacattttt agaaaaactt
     4981 gccacgttgt ttaaaggttc caacattgac tgatacatgg aatcatttga ttgtaagcta
     5041 aatgtatctg tgtcgatcag cttctcagct tctttgagaa actcatccat tttatctgga
     5101 tcagatagag tgtaaatagc agaatctatc gtgttatcgt cagatgtccc atttagttca
     5161 tttgcaaaag tgtaagaagt gtaaagtgta ttcgacggat tcatgaagtt gaatttcata
     5221 cccatactgc cgcttgtttc gctggattca taaattcctt tgatcgtcat ttcataagtg
     5281 gtatcttcat cttcagtact cgtgattgtg aaagtatctc cgactgccag gtcatttgtt
     5341 tctgctagag tagaatcaat gactacattg tttgtgcctt tgtcgctgtc atctattcct
     5401 tcaccatccg tgatttttgc tgttccatca gaaaaattac tattttgtgc agttgctgac
     5461 acaccactga tttgaaagtc tgcttgagtc atttgcggat tcccgcccat tcctccagca
     5521 ggttcaccgc ctgcatcagt agtttctgaa ctgtcttcac ttgaatcaga actagtgatg
     5581 gcagttattc catcttttgc catagctgag gcggaacttt caaaggaata actctttaca
     5641 ttatctaatt cagctatttt ttccgcgtcc gttaaggaaa ctggtgtaag agaaaaactg
     5701 cctggatctg gacgttcttc agtggtagaa ccgcttgaag aagtttgttc ctgtttttta
     5761 aatgaagctt ctcgattggc acttaaagtc actgttgctc caacttcttt ttgtgcttga
     5821 ttcgctgctt cttctgcagc gcttcgaatc gtgaggccag ctagcacaaa aataagaatg
     5881 gctgtgaaca cggcaaacaa taacaatgaa cgtccccatt ttacttttgt acttttccat
     5941 gcacgtttca taaaattcat attttgcatc cctcctagta gatgcatttg ataatagaca
     6001 acctatctta aagctagctt aaatcttatg ctgtttgcac accatcaaca tgaggttctg
     6061 tatatataaa aagtcactat agttattgca aaaaatgtgg taaaatgaaa aaagtatgtt
     6121 tcaaaccgac gaagaagaaa tgaaagagga atagcaaaag aaatcctaga tgctacagag
     6181 ggatttttac gtgcatagtt gttctaacaa ttgctgatac tagcgattta gtttatttgt
     6241 tgtataataa tggggaacag ctgaatactt atataagtat tctggctata gcgtttcgca
     6301 aaagatccat tttgttaatg aagtatatcc aaaataaaat gcccatccaa ctgtcagaac
     6361 gcggatgtgc tggtaatttt cctgctgatt ctccataagt tgagaaatag tgattttgca
     6421 tatgcttcat tggaatggct catatattta gataaagaag aaaatcgaca tctttaaact
     6481 tggatgtcat aagaagaggt gaagtttgtg agtaccatta aaattatccc attaggcggc
     6541 gttcgtgaaa atggaaaaaa catgtatgtc gcagaagtgg gcgaggatat ttttatttta
     6601 gattgtgggc taaaatatcc tgaaaatgag ttgttgggga tcgacgtcgt aatccctgat
     6661 tttacgtatt tagaagaaaa cattgatcgt gtagctggtg tctttttaac acatggacat
     6721 gcagatgcga tcggggcact tccttacttg ttgtcaaaaa tttctgtacc agtattcggg
     6781 acagagttga cgatcgagtt agcaaaattg aatgtcagtc gtaatgaagc agccaaagga
     6841 tttaaggatt tccatgtggt agatgagcat acagaaatag actttggtga aacagtagtg
     6901 agctttttcc gtaccactca tacgatacca gattcagtgg ggatcaatct gaaaacaaaa
     6961 gaaggtagta tcgtttatac gggagatttt aaatttgacc aaacggctat cccaatgtat
     7021 caaacagatt atgcacgatt ggcggaaatc ggcaaagaag gagtcttagc cttactaagt
     7081 gaatcggcaa atgcagaaaa tcctcagcct gtagcttctg aagcccaaat agcagatgaa
     7141 gtatttgata cgatcaaata ttgggaaggg cgtatcatcg tcgcttgtgt agcaagtaat
     7201 ttgcaacgag tgcaacaagt attggatgca gcagaaaaag cacaacgaaa agttgtcttg
     7261 actggtcaag atttcgaacg aattattcgc acagcgatgc gtttagaaaa acttcaatta
     7321 ccaagtgaag atctgcttgt tacgttgaaa gacatgaaaa actatgatcc agaagaactg
     7381 atcattttag aaactggccg aatgggtgaa cccatcaagt ctctgcaaaa aatggcaaac
     7441 ggtacacacc gtaatgtcaa gattgaagaa ggagatttgg tttatatcac tactacgcca
     7501 agcatcgcga tggaaaccat cgtggcgaaa acggaagata tcatttatcg agctggtgga
     7561 acagtgaagt tgatctctga gaatatgcgc gtttctggcc atgccaatcc taatgacttg
     7621 caattaatga tcaatttgat gaaaccaaca tattttgtgc cagttcaagg agagtatcgt
     7681 gaattagctg ctcatgcaga tttggctcat gcagtaggga tgccatacaa aaatatctat
     7741 attactggac gcggagacgt gctggaatat aagaacaagc gtatgagtgt tgcaggaact
     7801 acaagtgcag aaaatgtaat gattgatgga ttaggcatag gtgatatcgg aaacattgtt
     7861 ttacgtgatc gaaaaatctt gtcagaagac gggattttcg tagcggttgt cactatcagt
     7921 cggcgagaaa agaaaatcat ttcaaaacct caaattactt cacggggatt cgtttacgta
     7981 aaagctagcc gtgatctgat gaaagaaagc agcaatatga ttgaaacaat cgttgagaaa
     8041 catttagaaa gcaatgattt tgagtggagc aaattaaagc aagacatccg agatcaatta
     8101 ggccgttact tatttgaaca aacaaaacgc cgcccagtga tcttgccagt cattatggaa
     8161 gctactcaac gtcgaaataa aaaataaaca aaaagagtaa gatgaacctc tctatagagt
     8221 gctcgtcttg ctcttttttt gcgaaaaaca aataattttt gaatacagca tccctcgctt
     8281 tataataaac gatagaataa agggagtgaa tcaatgatga gtcaaacaaa agtcgaacgt
     8341 tatttagaag aacaaaagat cagctatcaa ccacttgatt ttagtcatgt ggtagaagaa
     8401 tctttcacag aagaactaca aaaaagaggg attgatccag ctttgatatg taaaactctc
     8461 gtagtgaaag gaaacaaaac tggggtgatc atcgcattga ttcctttgaa cgatcactta
     8521 gattacaaaa aaacgagaca agtgacgaaa gatcgtaaag ttggttttcc tggaatggat
     8581 tttgtattaa tgcatacagg atatccccac ggagcaaaca cccctattgg aataaaactc
     8641 gcacatcctg attattgttt tttagcagac agttctttaa aagaaaaaga agaagtaatt
     8701 gtgtcaagcg gtgaaatcgg gagaagcctt cggataaaag tagccgattt agaaaagatc
     8761 gtccatccta tttacgctga tttaattagt taagggacga gaagagaagc taagcagagc
     8821 agagacctca aacttgagat tatatctgct tggtacttgg tgcatcctgt attatctgtt
     8881 acaattgctt tgtacatact gtactatcaa tccaatgaaa atatatttag cagctatatt
     8941 ttttcattga tgtgcaagtg atgaaatcgt ttttaataaa aaagatacag agaaaacgcg
     9001 aggtgtaaaa tatgaaaatt acgtatcatg gacattcctg tttaacaatt gaaatggaaa
     9061 atggccaacg cgtgatgatt gacccgttta ttacaggaaa tccattgaca gacttaactg
     9121 cagaagaagt aaagacagat tggttgctga ttactcatgg tcatagtgac cacataggag
     9181 atatgattcc tattgcaaaa gaaaatcaag ccacaattat cagtattgtt gagattgctg
     9241 attatgcgaa cagcagagga gtagattcat tcggtatgaa tatcggtgga aaacatgcgt
     9301 ttccattcgg cgtggtaaaa ttcgtacatg cacagcatag ttcaagctat gaagtagacg
     9361 gtatcgttca gtatatgggc gagcctagcg gaattattat tcaagcagaa ggaaaaacga
     9421 tttatcatgc aggggatact gcttatttca gtgatctagg attgcttgca gaagaattcg
     9481 atattgatgt cgctttcttg ccgattggcg ataactatac gatggggcca gaagatgcag
     9541 caaaggctgc gcaaacaatt cgtgccaaga aagtagttcc aatccattac aatactttcc
     9601 ctgtcattga acaagatccc gaatcttttg tagagttact ggaagatagt gaaggaaaaa
     9661 taatgagcgt ctcggaaacg ctggaagtgt aggcagaaaa tggcgacaaa acatgatttg
     9721 attttagaat atattgaaag tttacctgtt ggcaatcgaa tttctgtaag aagcatcgca
     9781 aaagaattga atgtcagtga aggaacagcg taccgtgcaa tcaaagatgc agaaaatgtc
     9841 ggactagttt caacaattca acgagtaggg accatccgta tcgaacgcaa attaaaaaaa
     9901 catattgaac gtttgacatt tggcgaggtc gtcaggatca ttgaagggga cgttttaggc
     9961 ggggcggcag gattagacaa ggtcttgaat aaattcgtca tcggcgcgat gactaaacat
    10021 gccatggaac gctatattac gccaggatca ctaatgatcg tcggcaaccg ggcggaagtc
    10081 caaaaattag cattggaaga tggcgccgca gtattgatca caggaggatt caatacgact
    10141 gctgagattg caaagctagc tgatgatctt gaaatgccga tcttacgcac ctcttatgat
    10201 acatttacag tcgcaaccat gatcaaccga gcgttaagcg accaattgat caaaaaagat
    10261 atcatgcttg tcagtgatat ctatatgcca gctgaaaaga ctcattattt gcagcagaca
    10321 gatacgattt ctgattatca gcgtttgtca gaagaaacgc agcattcgcg ttttccagtc
    10381 gtcaaccgcc atcatcgttt gatggggatt gttacggcaa aagatgtttt agggaaatcg
    10441 ccaaaccaga tcatcgatcg ggtgatgacg aaagaaccaa tcagtgtaaa gaaaacaatg
    10501 agtattgcct ctgttagcca tcaaatgatc tgggatgggc tagaagtcat gccggtcgtt
    10561 tccgatgact tgacattgga aggcttgatt acccggcaag atgtaatgaa agcgatgcag
    10621 cttgtccagc gacaaccgca gattgcagat acgatttcgg atcagatatc tggaaatatc
    10681 catacgattg atactgaccg tgaaggaaat cgtttggaaa accctaagtt caaattcgta
    10741 gtagcaccac aaatggtcaa tggcgttgga accatttctt ttggcgtact tagcgaaatc
    10801 atttctgatg tcgcacaaaa aacaatggtg atgaaccaaa aacgaaatat cttgattgaa
    10861 caagtgaacc tacattattt gcggctgatc caattggaaa gcgaattaga cattcgtcca
    10921 cgtgtattgg aaatcggcag acgttccgct aaactggata tcgaagtgtt tattgaaaac
    10981 accatcgttt ccaaagcaat cgttgtttgt caagtaatgg aacgttctta gaaagcagga
    11041 gtgaaatgac agtacagcaa gaaatagtag atacaataaa aaaatacgat aaaatcatta
    11101 tccacaggca tttgcgccct gatcctgatg cattaggatc acaagtagga ttagccgaac
    11161 tattacggga aagtttccca gaaaaagaaa tacgtcaagt aggtgaaacg attgaagggc
    11221 ttcgcttttt agcagaaatg caagaagttg aagatgtctt ctaccaagga gcgctagtca
    11281 tcgtgactga tacagctaat tcacccagaa tcagtgatca aagatatcag ttggcagaaa
    11341 aactgatcaa aatcgaccat catcccaatg atgaccctta tggagatctt gtgtgggtaa
    11401 atacaaaagc aagtagctgt agtgagatga ttgcagaatt tgctttgatg tttcctgaat
    11461 ctttaaagat gaacgttaag gctgcacggt tactttatgc aggaatcgtc ggagatacag
    11521 ggcgcttttt gtatccctcc acgacgtccc gtacattaga gattgcttcg atattgagaa
    11581 attatccatt tgatgcaagt gctttgaaca gagagattga acaaatgccg atgaaagtcg
    11641 ctaaactttc cggttatctt tatcaaaata tccaggtgga tgaaaatggt gcaggaagaa
    11701 taatccttcc gcaagaaatt cttgataaat atggaatcga tgattcagag acagcttcga
    11761 tcgtttcact tcctggagtg attgacgaag tgctggcttg ggggattttt gttcagcagc
    11821 cttcagggta ttaccgcgta cgtttacgtt ctaaggggcc gatcatcaat gaattggcta
    11881 aacgccatca tggaggaggc catccattag caagtggtgc gaatgcaaaa gatttagcag
    11941 aagtagagga aatctataaa gagatccaag atatatgcca atcgtataag agcagaaaaa
    12001 cagaatgata cttcgttcga aaacgtgcct tttgtagtaa aaatcacaaa tgtatctttt
    12061 caagatcttc tttttccgtt acaatagtgc tcactaaaga ttttaaagga gaaagaagat
    12121 gacattacca aattgcccag aatgtggctc agagtacaca tatgaagatc gaggcttgtt
    12181 gatttgccca gaatgcggga acgaatggaa caaagaagaa caagaaactg tcatagaaga
    12241 cggattagtg gtattagatg caaatggaaa ccgtctgtta gagggcgata gcgtgacagt
    12301 gattaaagac ttgaaagtaa aaggtgcgtc aggtgccatt aaacaaggaa caaaagtcaa
    12361 gaacatccgt ttagtagaag gcgatcataa tatcgattgc aaggtagaag gatttggacc
    12421 gatgaaactg aaatcggaat ttgtgaaaaa gaattaaaga atattcaagg tcttttcaca
    12481 ttcttttcct actactaatg ataaaataaa gtaaacgaaa aggagtgaaa cgaaaatgta
    12541 tggttatgga atgtatggtt ttttagatcc gacatttctt ttggtcattc ttggattagt
    12601 tatttccgga attgcgtcag cgtacgtcaa tagtactttc cgaaaatacg atcaagtgag
    12661 aagcaaaaac aatgtgactg gtacacaagc agcacaatat atattacaaa gtcaacagat
    12721 aaataatgtc ggtgttcaac aaattgccgg agatctcaca gataactaca attcaggtaa
    12781 taagatgttg agtttgtctc aagcaactgc acagtctact tcagttgctg cgataggtgt
    12841 agcagctcat gaatgcggac atgcggtaca agatgcttcg ggttatgtcc cattgaagat
    12901 tcgtgcagca cttgttccag cagctaactt tggttcgatg atttcgttcc ccttgattat
    12961 ggtaggtgta ttgcttagct ggaactctac gttaatcaat atcgggattt tcgctttttc
    13021 tttagcatta cttttccaat tggtgacatt accagtcgaa tttaacgcgt ctcggcgagc
    13081 aatccaaatt ttgagtgaag gcggactact gacggaagaa gaagtaccga tggcaagaca
    13141 cgtattattt gcagcagcac tgacttatgt tgcagcagcg ctttcgacat tcctgcagct
    13201 gttgcgcttg atcttattgt tcggcggcaa ccgaagagat taaaataaag aagttgtgaa
    13261 atcagcgctt tgatctgagc taataccgag agttagctga ttgaatacca tttatttgga
    13321 ataagaggat gtgacaagaa ttttgtcaca tcctctttgt tttgttctca taaccttttt
    13381 tcatatacag ttcatgaacc gcttttatta acttgccaaa taacactgta ttgtgcgttg
    13441 tatccagata gaaagtctcc gtttcatctg aaattttctc atgctgatct gtaatgatca
    13501 aatcagcatg ttctgaatat gcggtaattt taacagcatc tttgcgaaat aactgctgca
    13561 aatggctttg aagatgataa tttcctgtaa actgtttggt tatctgcaaa tggatgagta
    13621 actgctcttt cgtttctgtt tgtagtaagt gttggatcaa ttgactaagg tattgactga
    13681 tttggtttct ttccccattt tttgaaaaaa ttgtatcgat tttttctctt aatttctttt
    13741 cctgtataaa agaactagaa tgattggacg tggcttctgg aaagcaaagt gtagaaaaac
    13801 tactgctgga ttcacccaac agttcgaaaa aaacaactgc caacacaaga aaataaaaat
    13861 aaattggtat tttattttct aaatggttga gaggaaactg ttgagttaag taagtcatca
    13921 attgaccgac ttgtcgacaa ataaggtttt tgcttgtgga aaataaaaaa ccaatctcct
    13981 gtttttgtcg aaaagagatt tgatttggaa aaaaacaata gaaaaaataa ttaaagtagg
    14041 ctctctctgt ttctgtctct tcacaagggc gactcactga aaaagaagta aagtattctg
    14101 aataatcatg tgtatgctgc aataagtcca tcaattcagt gatttcagaa gaagtttttg
    14161 gaaaatatgc ctgttgtttg tttcgtaata tgaataaagt taacagcaag tagatatttt
    14221 tttcttgttt tgaaattttt tctatttgct catctgtact gttcattttt agtgcattta
    14281 attcaagtga ggaaaatggc caatcgttac ctccaaatgt atctgaaaga aaaaagtaaa
    14341 gatagagacg gatagataac tcatttcctt caagagtaca gcaatttttt acagatagga
    14401 tccgtaaatg gaattttttt aaggaatgat tgagctgttt tgtcagtttt tcgagatagg
    14461 agggcgatat ataaagttgt tcaagtaaat atttttttgg tacagcagtt tgtggataat
    14521 tgattagtaa catcaaatag ttaaaacgat tggattcttt taggtagcat aattttaact
    14581 tagaaaaaac agctaacttt ttagtttgat cggtttcttt ggtttggatc tctcctttat
    14641 gattagaata aataaattca tcaatcaata aaaattgctt gagtgataca tttatttttc
    14701 ggatcagttc tttgattgtc cgttttggaa tatgtaagtc attggataat tcttgtaaag
    14761 aacaattatt tttttgaatg accatttgta gaacaagtaa ctcttttttt cttgcttcaa
    14821 ttagcataaa tacctccttt ttattctgtt tttgtatata gttagacaaa aactgtgagt
    14881 ggaaagtcat ttcagtctgt gttattctca cagagtgtcg ccttcttttt tatataacgt
    14941 tatttaattt ttttgttacc ttgtttattc tattgtttat ttcctagggt attttgtcaa
    15001 gatattcttg tttttaaggc ggaaaaattg atttttaatg gatataacta aatatgtttt
    15061 gataattatc aataatattt ttagaattat ttatgttatt tatttatggg tagatgaaaa
    15121 gagacggagg taagaatgat ggggagagta acaaattata gtaaagaata tttgctgttc
    15181 aaaagtatgg tatacgtgga agaatatgga atgaagtcaa ttactgcaag agagttagca
    15241 gagttctgcg gttgttctac atacccgatt tatacacatt tcaaatcaat cagcgggtta
    15301 aaagagaaga tattagaaga aatcactgtt tattttgaaa actacttagc tgaatgcagt
    15361 tccgatgatg ttttaagcat tgtctactta ttgaaagatt ttttttctat ccatgaaagt
    15421 attcgtgaaa tcattgcaaa atctgattta gacatggatt cgctatttaa gcggccattt
    15481 ttctcatatg tcaaaggtca cacgaagatc aaagaagaaa agtcgcttga attggtatgg
    15541 cttaatgcat tgggaagttt gcgctcagat gattcttctc aagattttct tgaaatgatg
    15601 aacgctgttt gggataaaaa cgaggtgacg gatgaatact tggaaaatat cttaaaggaa
    15661 cagtcacctt aggcagcaac atgaaaaagt agatcagcca cctttatttt tcgtaaaaaa
    15721 gattgtaaaa tgtctaacga aacattggaa tgaaggagga agcgacaacg ttaccacagc
    15781 aatttatcaa aaaatatcgt cttcttttag gcgaagaagc atccgatttt ttttctgcgc
    15841 ttgaacaagg aagcgtgaaa aaaggatttc ggtggaatcc actaaaaccg gcaggattgg
    15901 acatggtcca aacttaccat agcgaagaat tacaacccgc tccctacagc aatgagggat
    15961 ttcttggcac tgtcaatgga aagtctttcc tccatcaagc tgggtatgaa tatagccaag
    16021 aaccaagtgc aatgatcgtt ggaacagctg ctgcagcaaa acccggtgaa aaagttttgg
    16081 atttgtgtgc ggctcccggt ggtaaatcaa cccaattagc tgctcaaatg aaggggaaag
    16141 ggttattagt gacgaatgag atctttccga aacgtgcgaa gattttatca gaaaatatag
    16201 aacgatgggg agtttcgaac gcaatagtga caaatcatgc acccgcagaa cttgtccctc
    16261 atttttcggg cttttttgat cggatcgtgg ttgatgctcc ttgttcagga gaaggaatgt
    16321 tccgaaaaga tccaaatgca ataaaagagt ggacagaaga atctccgcta tactgtcaaa
    16381 aacgtcagca agagattttg tcttcagcaa taaaaatgct aaaaaataaa ggacaactga
    16441 tttattcgac ttgtacgttt gcaccagaag aaaatgaaga gatcattagc tggcttgtag
    16501 aaaattatcc agtaacgatt gaggagattc ctttgactca atccgttagt tcaggacgtt
    16561 ctgaatgggg aagcgtagct ggtttggaaa aaacaatacg tatatggcct cataaagatc
    16621 agggtgaagg acattttgtt gcaaagctga cttttcatgg acaaaatcag atgcataaag
    16681 aaaagaagac acgaaaaaaa agtaaagtgc aaatgacaaa agagcaggaa aaactctgga
    16741 cggagttttc aaatgatttt cattatgaag ctactggaag acttttagtg ttcaacgacc
    16801 atctttggga agttcctgag ttagcccctt ctctcgatgg tttaaaagtc gtacgtacag
    16861 gtttgcattt aggagatttc aaaaagaatc gatttgaacc tagctatgca ttagcgcttg
    16921 ctacaaaaaa gatagagaat ataccttgct tgccgatcac tcaaaaggaa tggcaatctt
    16981 acacagcagg agaaacattt caacgtgatg ggaatcaagg atgggttttg ctagtattag
    17041 ataagatacc tgtcggattt gggaaacaag taaaaggaac agtaaagaac tttttcccta
    17101 aaggattgag atttcactga gtggattagt tcgtttattt ttttgtctat gctatgatgg
    17161 agatagataa aaaggagctg atacttatga aaacatcaac aaaagtaaca atcggattaa
    17221 gcgtagcagc cgctgccagt gtagcgacag cagtcgttgt atcgggaaaa gtaatggaaa
    17281 agatccatca tatgactact cggacgaaag taaaaaaatt cgtctatgac aaatttgatg
    17341 gaaatgaaaa attactagaa atcgtagatg gtctttcaga tagtgacttg gattctttga
    17401 tgggaatgtt agcaaaaatc aaatcaggaa aaaagaaaat ctctgtttat ggtgattcaa
    17461 tcaaagattc aaccgaagat gtaaaagacc ggctaatgca ttttgttgaa aaaatgatgt
    17521 aagagaaact agcttttgaa cactattcat tcgaaataag gggttgtgac aaaattattg
    17581 tcacaacccc tttaatctat ctttaattat gttcatgaag caataaaaga tagcaaaaca
    17641 gtaaatcgtt ggcttttttt agattgaaac cagactgttc ttgaaatttt tcgattcgat
    17701 attttagagt attacgatga agaaacagtg tttttgcagc agagctgaca ttgcctaatt
    17761 cattccataa ttcttgaatg atcacttcca tttcattttg tttgatcagt tctatgtaac
    17821 ttttgatcaa cttactatct tttacagtat cttttgtata gtaatgtaaa gccacatctt
    17881 gcatagaaaa agtacggctg tgagtataaa gattgttttg ctctgttaaa aaaatttttc
    17941 tttcttcagc aaacaaaggg acgaggtcgg tgccaggtga atggaaagaa ccaacgaata
    18001 cagacgttgt cgtatcaaaa tcagcatcta aagatagaaa aataccgttg atttcagtag
    18061 catcaagata atcacggttt atttgttcga ctaagagcgc atctgtgtct gtataaaaaa
    18121 agaaatcagc agaatagcga aataattcca aaatagtatc ttgccattct ttttttaaga
    18181 attctccttt tgattcgacg tgaagctgga tcaaacgaaa gcttttttct tgaacacaag
    18241 aagcatcttt aaaaagatag tgataccatg ggtgtttttt ttgatcgttg attacaggga
    18301 ataacgcttt caaaaggctg gtttcttgtt gagataatga atcttgtttg atccagataa
    18361 aagcatcatc aattgcaaaa gaaaggatat ccgcttctga tgctggagag ttttttttct
    18421 gtgcttgtgg gtaaagagca agtaatttat ccattttcat cttgttcacc tcttgtattt
    18481 attttaccat agaaaaaaaa gttagttaca gcctttttat catatgctaa agtaaaacaa
    18541 gaaaaaacaa aggcagggaa gggtaattgg taaatacaaa tcttgatgca gtagaaaaag
    18601 aaaaatggat gcgccttgca ttggcagaag caaagaaagc agaaatgctt catgaagttc
    18661 cgattggagc agtggttgta ttggatggaa aagtgattgg aagaggatat aaccttagag
    18721 aaaccacgca agatgctact acacatgcag aaatgcttgc aatcaaggaa gcctgtgaaa
    18781 aagtgggaag ctggcgcttg gaagatgctg cactttttgt taccttagag ccttgtccta
    18841 tgtgcagcgg cgcgatgatt ttgtctcgtg tagcagaagt ttatttcggc gcgtatgatc
    18901 caaaaggcgg aacagccggt accttgatga atcttttgga ggacgagcgg tttaaccacc
    18961 aagcatatgt agaaggtggc attttagaag acgaatgtgg gatgattttg actgactttt
    19021 tccgaaagct ccgccagcga aaaaagaaat taaaaaaaga ctggtcaacg aatgaaaaat
    19081 aaggtatact attctttgcc gaaaggctag gacaatggtg ggcttgtgaa gcgtgtcagg
    19141 tctggaagga agcagcacta agcaggttcc gccatgtgtc tgattataat gaaacgacaa
    19201 cagactttcg ggtctgtttt ttttattttt atagtactgt aaaaatgaat gttcctgatt
    19261 ttttagccag actgatttat cgaatattgt acttatacaa tttgcttcaa ggcaggaaaa
    19321 actctgaaat agagcttgtt tcaatggaag aaaaagctgc ctatggtatg ataaagataa
    19381 agagaggcga gagggtacat ggaaaaaata gtgattttac atacgaatga tctgcattct
    19441 catttagaaa attggccaag gatcagaagg tttttggatc aacgtaaacg agaaaacgaa
    19501 aagaaagaaa aaacgacaac gattgcagta gatctaggtg attttgtgga tcgttggcat
    19561 ccattgtcag aagcaacgaa tggacaggaa aatatcttgc tgatgaatga agttggttat
    19621 gatgcagcga cgataggaaa caatgaaggc gtaggaaatt ccaaagaaga gttgaatcat
    19681 ttatacgatc atgctgagtt tgatatcatc ctggataact tattcgataa aaatacgctc
    19741 cagccaccgg catggacgaa accatataaa atcattacaa cgaaacacca gacgaaaatc
    19801 ggactaattg catttactgc tccatttccg cttacttata atccgaatgg ctgggacata
    19861 cggaatcctt atgatatttt gccagaatta gtcgaagatt tacgttcaca agtggatgtt
    19921 ttagttttga tgagtcatct cgggattcag gatgatttcc aaattgcaaa agaaatacca
    19981 gcaattgatg ttattttagg atcgcacacc catcatttat tcagagaagg tcacgtaatc
    20041 aatgatgtcc aaatagcagc cgctggaaag tacgggcagt atgtcggtga agtccattta
    20101 accatcgatg aagagaaaaa aatccttaag cattcagcca aagccatccc taccgaaaca
    20161 atgacagctt ttacagaaga tgaacaagaa ataaatagtt atctagaacg tgggcatgaa
    20221 ttattaaaag aaaaagaagt agcagatttg ccattttctc tgagtctaga tatcttcaat
    20281 gagcattcgt ttatccaagt agcctttgag gcggtgaaag aacgaggaaa gacggaagca
    20341 gcaatattaa acagtggtct gtttttaact gaaattccaa aagggcgggt caatcaggat
    20401 cagcttcaca ctgcgttgcc gcatccgatg cacttgttaa atgtcacatt gggtggaaat
    20461 gatctgatcc gcttagtttt agaaatagaa aaaaatcgta actttttacg taactatcct
    20521 atgaagggaa tgggatttcg cggtaagatt tttgggcaga tggtctataa tggaatcaca
    20581 tatgattcta ttaaccatca agtcttttgg aagaacaagc caatcgatct gaataaaaat
    20641 tatactttta ctaccgtaga tcatttgatg tttgttccat tttttccaac gattgagatt
    20701 gctggaaaaa atgaattttt gttccctgaa tttatccgaa gtgtggtagg agattacttg
    20761 aaagctcact acccaatcaa ataaaaacaa ggtataataa aaaagatagg tggtgaacgc
    20821 atgtctgcaa aacaaaatga acagcagaac gttgagcata aaacagaaat tgctaagaaa
    20881 aaatcatcag ctgaacagga aacaacagtc accgaagaac tgacagctgc tttggaagaa
    20941 atcgttgagg agcctaaagc agaaaaagtc aaaggcgagc tagtgacact gttagatgac
    21001 agtaattttt tgataggtga aagacattat cggcttgtgt ccgattatcg tgaaggattt
    21061 aatgcagaaa agcttggaga acgttacagt gatgtactag cccgatatga ttatatcgta
    21121 ggagattggg gttatgaaca actacgccta aaaggatttt tccaagcgga taatcgacgg
    21181 gcgcatccag atcagcgaat cgattccttg gaagactatc tttacgaata ttgcaatttt
    21241 ggttgtgcgt attttgtcat cgagagaatc ggcggtaaaa aagaaaagac aactcagcgc
    21301 cgaaaaaaga aaaaaaacca taatcgtgcg tatatcgatg agaaaaaagg accagtcgca
    21361 tctaatcgca aaaaaccggt tattaaaaat cgaaaaacag agtcagcaaa aacctctgaa
    21421 aaagtaaaaa aacaagaaca acctaaacaa gtagaaaaaa caaaaacagc atttacgatc
    21481 agaaaaaggg aagagtagtg gatgaatgga ctataaagga tatttaattg atttagacgg
    21541 aacgatttat cgtgggacac aacccatacc ggccggtaaa cgatttgtgg aagaattgca
    21601 aaaaagaaaa ttacctttct tgtttgttac caataacacg actaagtcac cagaaacagt
    21661 agctaatcgt ctagcagatg agtttgacat tcatgtagct ccagagacag tctacacagc
    21721 tactttggca acaatcgatt ttatgaaagc agatggaaaa gggaaaaaag tctatgttat
    21781 cggagaagca ggattgattg acttgatttt agctgccgga tttacatggg aagaagaggc
    21841 tcctgactat gtagtggtag gcttagataa ttatctgacc tatgaaaaag tagttaaagc
    21901 aacacttgct attcaaaaag gtgctacttt cattggaacg aacccagata agaatatacc
    21961 tactgaacgc ggccttcttc ctggagcagg gtcagtcatc tcttttgtag agacagcaac
    22021 ccaaacgccg ccgatctaca tcggaaaacc agaagccatc attatggata aagccgttga
    22081 agtattaggg ctgcaaaaag aagaagtaat catggttgga gataactatg aaacagatat
    22141 ccaagctggg atacgcaata atatagatac tttgctcgtt ttatcaggtt ttacaaaaga
    22201 agaagatgta cctgggttgc ctatcccagc tacctatgtg aaacaatcac tggatgaatg
    22261 gagcttctaa tatgaaaaat tcgagatggc agtggatgga atatgctgga ttgttcagcc
    22321 tatttctgac actgatcagt ctggcagttg gtgtgacgat caactttcga ccactatacg
    22381 tatttgatat cggacatttg caaattttgg attatacttc tttagatcaa gagacgttac
    22441 tgaaaaattt tgatcaccta atgaattatc tcaataatcc cttcaaaacc atcctcagct
    22501 tgccagattt cccagtttct gctagcggag cccatcactt ttatgaagtg aaaattttgt
    22561 ttttagtgga ttatgctgtg tttttcatca ctttgatccc gagtattttg tttatcaaat
    22621 atttgcaaaa gaatgatcgg ctttggcggt tgattcgtcc gtttcaaatc ggcatgttac
    22681 tgccagttgt tttcggtttt ttcatgatga taggatttga tcgctttttt atcctttttc
    22741 atgaaacgtt tttcaacaac gatgactggt tattcgatcc cgttactgat ccaatcatca
    22801 atgtacttcc agaagaattt ttcatgcata gctttatctt attttttgta ttattagaat
    22861 tattttttgc tgtttttctt ttcttaggaa aaaatagctt gaaacaaaca aaaaagaaag
    22921 aactcgtcta aatagacgtt ttctttcttt ttttgttgaa ttattgagta aggcgacttc
    22981 ttttttctgg ttctttgtgt gctaatcgac tggcagcagc agcggcgatc gctccgacga
    23041 tatcatctaa gaaggtatgg acatgaacgc catcgtggct gtttagttct tttaaaatac
    23101 caggtttcac cttgtcgata taaccataat tcgtaaagcc gatcgtaccg taaacattca
    23161 cgattgacaa ggctaggatc tcatcgatac cgtaaaggcc ttcgtcatct tcgataatat
    23221 gttgcaacgg actcatcaat tttttctttt ctgctaatat atctaattgg attccagtga
    23281 taatggcgtt atgtacttca cgctttgtta gcacgctgtt gacactttca gtacaatccg
    23341 ccaaagtcaa atcagaaata tagtcttttt gtaaaaacat gacaagttgt gcgatatctt
    23401 ctacagttac gccacgttcc ttcaatagtt ctcttgcctt ttcttctaaa gtctcagttt
    23461 tgacgaccat attattgctc cccctttatt ttttctttct ctatttcatg ttaacggaac
    23521 atgaaaaaaa tgcaagaaac tgctttcggg tttaacttga aatgcaaaga gatataaaaa
    23581 atcaactagg acgaagattt ttatcgtata agcttgtgct gtgaccaggc tgagttcgtt
    23641 cctttggatt aatatagtgt aaagcgttgt tcactgcagt aggtgcttca ccgagcccag
    23701 tagcaatcag tttcactttt ccttcatagg tacagatgtc accagctgca taaacgcctg
    23761 gaatagaagt agacatatct gattttacag taatggcatt tctggtacta tcaagtcccc
    23821 aagaagaaag atgttctaaa ttagaagaga atccataatt gacgatcaga gaatcaatca
    23881 tcaaatcaat cgtctcgtca cttttcactt tttttaaccg gatatctgtc agttccccat
    23941 tattgcctga taatccatcg atgagatagg gagtaagcaa gttgacagat gaagatttca
    24001 agcgtgatac actatgttcg tgcgcacgaa attccgggcg acgatgaatc aagtaaactt
    24061 cgcttgcaat aggctctaac atcaacgtcc aatcgatagc agaatcacca cctccagcaa
    24121 tagcgacttt ttttccagca tacttcatca aatcattcac gaaataatcc aatccgtggt
    24181 tttcaaatga ttcagcatta tctaaattca attttcttgg ctggaatgaa ccatttccta
    24241 aagctaaaat gactgctttg gaataatgga tgcctttatt tgtagtaatc tcgataactt
    24301 cgtcttcacg agtaagcgag agaacttctt cttttaaatg gaatgtatgg ttaaaagtag
    24361 ttaattgttt ttctaattga tcgattaatt cacttgcttt tattgctgga tacccaggaa
    24421 tatcgtaaat atatttttcg ggatacaaag ttgctaattg accaccaagt tgaggtagac
    24481 tgtcaatgat ttttgtttta gcttggcgca ttcctgcgta aaaagcggca aacatcccta
    24541 caggacctgc accgatgatt gtaatgtcat agatttccat aaaaattcct cccttttcac
    24601 actatagcag aatttaattg agaatgcttc tcaaaaatgt ttgaattcga aatcgaaacg
    24661 gtaagttata gaatgtatct agtgatgaaa aataaaagaa aacaaatcta gtatttttac
    24721 gagaggttag gtattatgtt attattatta tgaagtatgc aaatattagg aggaaacaat
    24781 atggcattcc cacaactaga tttaaaaagt gaaaaaggac caaaagctgt tatcaaaaca
    24841 aaccgtggtg acattactgt tcaattattc cctgaactag caccgaagac ggttcaaaat
    24901 ttcattgaac tttccaaaaa aggttattat gatggcgtga tttttcaccg cgttattcct
    24961 gatttcatga tccaaggcgg cgatccaact ggaacaggaa tgggtggcga aagtatttat
    25021 ggcgaaagtt ttgaagatga attcagtcgt gaactgttca accttcgcgg agctttatct
    25081 atggcaaatt caggtccaaa cacaaacgga agccaattct ttattgtaaa taacacaaat
    25141 gtgccagcta atatgcttgg acaactagaa ggtgctggat tcccatcaga aatcattgaa
    25201 gcgtataaag gtggcggaac tccttggcta gatttccgac atacagtctt tggacatgta
    25261 ctagaaggga tggacacagt agatgaaatc gcaaatgtac aacgtggtcc acaagaccga
    25321 cctgtacatg atgtagtgat tgaaacaatt gaaatttcag aatagtttgg tatggtacgg
    25381 agtaattatg aaaaaggacg aaacctagta aggtctcgtc cttttatttt gaataaatga
    25441 tttaatcgat tgtctctaaa gcatacttga ttcgattaag tccttccagt aaagtttctt
    25501 ctggacaagc aatattcaag cgcatatgcc catgaccgga aggaccaaac gtgatgccag
    25561 gatttaatac gacttttcct ttccgaacaa gagtgttctc caattcttgg tcgtctgaaa
    25621 tataggcggt aaaatctaac cacattaagt aagttccttc agggttcatt attctcactt
    25681 tcggaagata ctgttcaaaa aactgattaa ctgtttgaac atttttttct agataaggaa
    25741 tcagttggct taaccattct ccacccgtct cataagccgc ttgggttcca atcagtccaa
    25801 aagtgttgat ttcgtgctgt tggttcatca ctaaatgttt ttcaaaatca gctttcatct
    25861 ctggattttt gataaatacc attgaatttt tgattgcagc tagattgaaa gtcttggttg
    25921 cggaagtaaa agcaactagt agatcatcta aattaggatc aatcgttagc atggaagtaa
    25981 atgtatgatc gaataaagtt aaatcttgat ggatctcgtc actaaacaga atcacttgat
    26041 gttttaaaca caattcgctt aactgtttca attcttcttt gctccaaaca cgccctccag
    26101 gattgtgagg attgcataaa atcattgctt ttacattgtt ttcttcgatt tttttctcca
    26161 tgtcagacaa gtccatgatg aaatgattat ttttttctag caaagagctt cgaacgatgt
    26221 gacgttgatt tgtttctata atagaggaaa atggaggata aactgggtca tgaatcaaaa
    26281 tagaatcgcc tggttttgta aaagtttgta ctgctgcagc taaactggtt aacacaccac
    26341 ttgtaaaaac gatattttct ttcgtcaact ccacagcatg gtgttggcgt tcccaatgaa
    26401 tgatagcctg atatagttta tcagacagag tggcataacc aaagattcca tgtttgatgt
    26461 attcactaaa cgctttagct accccaccgg gagacaagaa gtccatatct gctacccaca
    26521 aaggaagtaa gtcatccatt tgatatgtct cagcaattgc gtcccatttt acactttctg
    26581 tatcttttct tgaaatctgt ttatcaaatt cgatcatctt aagacctcca gtcattttcg
    26641 tcgcttcttt ttttgagcta tttacagtat aatgataaat gcgaagagag ggaagtagat
    26701 gacttataaa attggacaaa taattgaagg aaaagtgaca gggatacagc cttatggcgc
    26761 attcgtttct cttgataacg agacgcaagg acttattcat gtttcagaag tacaatccgg
    26821 ttatacgaaa aatatccatt cattgttaaa agtcggacag ccagtaacag ttcagatcat
    26881 cgacattgat gaatattcca aaaaaatcag tttatcttta agaacgttag aaaaaacaaa
    26941 tccagctgtt ccatatcgca gaaaaaggta tttcacgaat aaaaatcgta agatcggatt
    27001 taccactatt gcggagcagt tacctatttg gatagaagaa gcattatctg aactagaacg
    27061 gaaagaaaat aagaaataaa aagtgtattt tttctgaaaa tgtgctagaa tttttatgta
    27121 agccatagaa caagttgatc gaggtggaaa ttttggcaag caaaagagtt gctggtacaa
    27181 ttatgttgca tttggaggat ggtactaaaa aatttttggt ccattcaatt gatgacaagt
    27241 tggaatttgc gttagcggaa ctttctgaag gaaagactgg tttagcgaat atacttaatt
    27301 tcttaaaaga aatagttcat atcgatgtta gcaagattag tttgatggaa ttgacaaata
    27361 cacatattaa agaggaaaat gttccgttgt ttgtctttga aactgaacaa aagaatcaaa
    27421 gagaagaatt aggcgaagga tatatttggg aagaaccagg tcaaatgcgc tctgttcttg
    27481 gaacttacga agtagaggga gtgcctttct tctaaaatac agattaagcg aacaaagaag
    27541 tttgaatttt tttcaaactt ctttttttat tgtttggtcc aaaaaataca atgaaatgtt
    27601 ctgctaaaga tagtttttta gtgcatttta ttttcaaaat atgttgaaaa cggttgtata
    27661 acgaataata ataattgatc gaaaaatcat ttcacaaagt aatgcttaat ttatagttga
    27721 ccaaggaaga aatacatgat aaatttaaca gcgttgattc tgaagtggat gttatatcac
    27781 atttctaaaa aatttaaaaa atagttattg acatgttact aacgacat
//
LOCUS       DAZKKZ010000037        27388 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.037, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000037 DAZKKZ010000000
VERSION     DAZKKZ010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 27388)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27388)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27388
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.037"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            162..392
                     /locus_tag="ACG8LA_001698"
     CDS             162..392
                     /locus_tag="ACG8LA_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 family protein"
                     /protein_id="HFQ0203999.1"
                     /translation="MQVYGIDAVLRIVSHLAFIYLAFWSLRSLRIETFFRPMHNTQIR
                     MAIVLFSIFLGYTASNFFLEVIALCRNLFVSL"
     gene            489..1790
                     /gene="murA"
                     /locus_tag="ACG8LA_001699"
     CDS             489..1790
                     /gene="murA"
                     /locus_tag="ACG8LA_001699"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008760 - UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0019277 - UDP-N-acetylgalactosamine
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HFQ0204000.1"
                     /translation="MEEIIVRGGNQLNGTVRIEGAKNAVLPILAASLLAEEGITTLDN
                     VPILSDVFTMNQVIRHLNVDVDFDEQKNQVTIDASRQLEIEAPYEYVSQMRASIVVMG
                     PLLARNGHAKVAMPGGCAIGKRPIDLHLKGFQALGAKIIQKNGYIEAIADELIGNTIY
                     LDFPSVGATQNIMMAAVKAKGTTIIENVAREPEIVDLANILNKMGAQVYGAGTETMRI
                     EGVDHLHAVNHSIVQDRIEAGTFMVAAAMTQGNVLIADAISEHNRPLISKLIEMGAEI
                     IEEEGGVRVIGPKHILPTDVKTMPHPGFPTDMQAQMTAIQLVAEGTSVVTETVFENRF
                     QHLEEMRRMNAHVKIDGNVAIMDGNHELQGAEVYATDLRAAAALVLAGLKANGITRVR
                     NLNYLDRGYYNFHIKLQQLGADVERVDMDQTSAEKTAQTIA"
     gene            1803..1979
                     /locus_tag="ACG8LA_001700"
     CDS             1803..1979
                     /locus_tag="ACG8LA_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HFQ0204001.1"
                     /translation="MSNQRYILLTLIKILVVILLLILLFVAGTMIGYGVIGGGNPFKV
                     FQPSLWIHIRDFFH"
     gene            2114..2410
                     /gene="yidD"
                     /locus_tag="ACG8LA_001701"
     CDS             2114..2410
                     /gene="yidD"
                     /locus_tag="ACG8LA_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HFQ0204002.1"
                     /translation="MKKILIYLVRGYQRFISPAFPPSCRYYPTCSNYMIKAIQTHGAL
                     KGTVMGTARILRCHPFVKGGIDYVPLTFQLTRNKKDKKEPDYKKVVKNTSSTER"
     gene            2594..3061
                     /locus_tag="ACG8LA_001702"
     CDS             2594..3061
                     /locus_tag="ACG8LA_001702"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFQ0204003.1"
                     /translation="MIEELNKKDLPWSLLLDADPDKEKVQVYVSRGSGWIWKEKEKTI
                     GVLIYVAREKEYEIVNVAVAPTYQGKGIGGKLLETAFQKLSQLASSQTQIIIRTGSTS
                     SAALHLYQKMGYVEIGRVKDYFIHHYSEPIFENGDQLRDQVILAIHLPKNSFN"
     gene            3146..4030
                     /locus_tag="ACG8LA_001703"
     CDS             3146..4030
                     /locus_tag="ACG8LA_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HFQ0204004.1"
                     /translation="MGILVFDFGGSAVKYGCWDGKEIKGKGQFATPESWEEMKAQLFQ
                     VYKKILVSFEVEGIGISSPGVVNNEKQVIEGISAIPYIHGFNIFRDLETLFQLPVTIE
                     NDANCAGMAEFYEGAARDYQDVAFVVAGTGIGGALFTKGQINKGAHLYGGEFGLMFLN
                     GDKTFSKLGTAVQMAWRYCERKGLDKNSYTGKDVFELAETGDAIAKEEVESFYTYLTK
                     GLFSIQFSFDPEVIVLGGGVSAKEGLIDEIKSRMKKLTEQFDLHDFEPQILLCEYRND
                     ANLVGAAANYLAVRQGEN"
     gene            4144..4380
                     /locus_tag="ACG8LA_001704"
     CDS             4144..4380
                     /locus_tag="ACG8LA_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HFQ0204005.1"
                     /translation="MMSKKNKDVEVRIEEVKKDIKGKNYEVTQLFIGKKMIGEILAYG
                     PKEYEIFFGEEDFGKEKSLENAIETVIRHWNLHE"
     gene            4468..4548
                     /locus_tag="ACG8LA_001705"
     tRNA            4468..4548
                     /locus_tag="ACG8LA_001705"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4502..4504,aa:Tyr,seq:gta)
     gene            4555..4626
                     /locus_tag="ACG8LA_001706"
     tRNA            4555..4626
                     /locus_tag="ACG8LA_001706"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4587..4589,aa:Gln,seq:ttg)
     gene            4751..4921
                     /locus_tag="ACG8LA_001707"
     CDS             4751..4921
                     /locus_tag="ACG8LA_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204006.1"
                     /translation="MKWKEKVDEAAEKLYDLVKSEKYNIEVNIPKKGGKAVQVKSKRP
                     TNHTKKWMAKNR"
     gene            5141..5848
                     /locus_tag="ACG8LA_001708"
     CDS             5141..5848
                     /locus_tag="ACG8LA_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFQ0204007.1"
                     /translation="MSNQLPVYIQIHDQLKNEIEQGIWKVGDRLPSERELAVKFNVSR
                     MTLRQAIQNLADEGILERKIGSGTYVAREKVQEKMSGATSFTEIMESQNRVPSSRTIS
                     YFLTSPSSSEMEKLNLSKDDTILRMERIRFADDVPICFEVASVPQKLIDGYSKAEITE
                     SLYRTLEEKGGKKIGPANQTITAVLASEKIADYLEVKRGDAVLRLRQISYFEDGTPFE
                     YVRTQYVGNRFEFYLEK"
     gene            complement(5908..6552)
                     /locus_tag="ACG8LA_001709"
     CDS             complement(5908..6552)
                     /locus_tag="ACG8LA_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HFQ0204008.1"
                     /translation="MIERYRTIKENGQSEIEIKKSRFICSLRRIESEDQAKSFIQEIK
                     KEHWKANHNCSAFIIGEKNEIQRSSDDGEPSGTAGVPMLEVLKKNQLINVAAVVTRYF
                     GGTKLGTGGLIRAYTHAVSQALSDIGIVEGTLQQEISVMITYPQLGKLQNYLELQHFF
                     IKEIQYTDQVSVICAVDEKSADHFKESIIELLNGQVQFEEGPVSYHEQLVTDHI"
     gene            6679..6966
                     /locus_tag="ACG8LA_001710"
     CDS             6679..6966
                     /locus_tag="ACG8LA_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204009.1"
                     /translation="MQERMKKYDAITHYLKNNGGSQVTLTFTQFDELLFPSNGLPKTA
                     RESTDWWANDYKHPEKGAYGWINAGYEVVVINLDKEYVVFNKLVKSSWLFD"
     gene            7074..7394
                     /locus_tag="ACG8LA_001711"
     CDS             7074..7394
                     /locus_tag="ACG8LA_001711"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFQ0204010.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEAKGIDSDIFAVSASDA
                     DNNLANKDVDVLLLGPQVRFMKADFEKRLEPKGIPLDVINMADYGMMNGEKVLDQAIT
                     LIGE"
     gene            7475..8788
                     /locus_tag="ACG8LA_001712"
     CDS             7475..8788
                     /locus_tag="ACG8LA_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HFQ0204011.1"
                     /translation="MNHFWGRRLLTRDIKAIDCEEVNLPNYEKIAAVERLGNWILCHR
                     CGMRTSVIDGQLADYGYFCTHCLYLGRCDTQQDLYLFDQPEAKPREVVFFWTGQLTEK
                     QTEIAKRILCHSEKRHHLIWAVTGAGKTEMLYPILVETLKAGGRVAICTPRVDVCNEL
                     FLRYRYVFPEEKITLLHGNTATAYTFTSFVICTIHQLYRFYRSFDLIVIDEIDAFPYN
                     GDAGLAHAVQTAIKPDGRFIYLSATPDKKLLKEIKQTFDIHKLALRFHRRLLPEPVLV
                     FMNNWRQKCKNKKKIKSLVRIIHQLIKENHILLFCPSITMMHRLKATLQEALPRYEIT
                     DVSSRDNQRAEKVQKMREAKYDILLTTMILERGVTFERISVIVLGADHPVFTKSSLVQ
                     IAGRADRKGPYTNSQVYFFYEEKTAAIRKACQEIKEMNEEGKKML"
     gene            8785..9504
                     /locus_tag="ACG8LA_001713"
     CDS             8785..9504
                     /locus_tag="ACG8LA_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HFQ0204012.1"
                     /translation="MRCSCCSKDIVQNLTFSEIIGVSKYRLPQTCSVCRAQFHLLETR
                     GCSGCQKPIHFNLESTKKKVKSIPVYCSDCQEWKKKYPTYDFQHRAFFVYDENMKAWL
                     NQYKFMGDIRLAGTFAYKWTQIKKEYPTYIYCPIPLSEKRRTERGFNQVSEMLKAARI
                     PFQMLLKREKHLLAQAKNTRKERLEMPQPFELAVTFSKIQNKKILIIDDVYTTGQTLF
                     HAADCLQVAQPKIIRTISLAR"
     gene            9632..10183
                     /gene="raiA"
                     /locus_tag="ACG8LA_001714"
     CDS             9632..10183
                     /gene="raiA"
                     /locus_tag="ACG8LA_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0045182 - translation regulator activity
                     [Evidence IEA];
                     GO_process: GO:0009386 - translational attenuation
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HFQ0204013.1"
                     /translation="MFRYNVRGENIEVTEAIRDYVEKKVGKLERYFSDAPDATAHVNL
                     KVYTEKTAKVEVTIPLPYLVLRAEETSPDLYASIDLVVDKLERQIRKFKTKINRKSRE
                     TGMNTADATALFNEEDENENDSELDIVRTKRLSLKPMDSEEAVLQMNMLGHNFFIFED
                     AETNGTSIVYRRKDGKYGLIETD"
     gene            10405..12939
                     /gene="secA"
                     /locus_tag="ACG8LA_001715"
     CDS             10405..12939
                     /gene="secA"
                     /locus_tag="ACG8LA_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006605 - protein targeting [Evidence IEA];
                     GO_process: GO:0006886 - intracellular protein transport
                     [Evidence IEA];
                     GO_process: GO:0017038 - protein import [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HFQ0204014.1"
                     /translation="MANLIRSLIENDKKELKRLDSIAKKVEAYADQMAALTDEQLQAK
                     TAEFKGRYQKGETLDQLLPEAFAVVREAAKRVLGLYPYHVQLMGGIVLHDGNIPEMRT
                     GEGKTLTATMPVYLNALTGEGVHVVTVNEYLATRDSTEMGELYNFLGLTVGLNINSKS
                     SDEKREAYNCDITYSTNNELGFDYLRDNMVVYRHQMVQRPLNYAIVDEVDSILIDEAR
                     TPLIISGQAEKSTALYTRADNFVKRLKEEEDYKIDIQSKTISLTEAGIEKAEETFGLD
                     NLYDIENTALTHHLDQALRANYIMLLDIDYVVQDGKVLIVDQFTGRIMDGRRYSDGLH
                     QAIEAKEGVEIEDETKTMATITFQNYFRMYKKLAGMTGTAKTEEEEFREIYNIQVYQI
                     PTNRPVIRDDRPDLLYPTLQSKFHAVVQDIKDRYRKGQPVLVGTVAVETSELLSDMLN
                     QERIPHEVLNAKNHFKEAEIIMNAGQKGAVTIATNMAGRGTDIKLGLGVRELGGLAVI
                     GTERHESRRIDNQLRGRAGRQGDPGMSQFYLSLEDDLMKRFGSERIKAFLDRMKIGDE
                     DAVIQSKMLTKQVEAAQKRVEGNNYDTRKNVLQYDDVMREQREVIYKQRQEVIMEEKS
                     LSKPLMNMVKRTISRVVDAHTQLEKENWNLESIVDFAGSTLVHEDSISLTDIEGKTSQ
                     EIKEYLNERAQEVFNTKAAQLNGPEQLLEFEKVVILRVVDSKWTDHIDAMDQLRQSIG
                     LRAYGQNNPLVEYQTEGYKMFEDMVGAIEYEVTRIFMKAEIRQNVQREQVSQGTASHS
                     EDGDAKENSNTSAKKQPIHVNKVGRNDPCPCGSGKKYKNCHGKDAN"
     gene            13066..14167
                     /gene="prfB"
                     /locus_tag="ACG8LA_001716"
     CDS             join(13066..13137,13139..14167)
                     /gene="prfB"
                     /locus_tag="ACG8LA_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_139124933.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0016149 - translation release factor
                     activity, codon specific [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HFQ0204015.1"
                     /translation="MEISEIRNLLTEMQEKVTSFRRSLDLDQLEEDIAEAEAKMAEPG
                     FWDDSEAAQKVISENNANKETYDQFHSLAEELEEIELMVEMLQEEPDAVMQEEAEARI
                     NALDEKMNTYELSMLLDGPYDRNNAIVELHPGAGGTESQDWGSMLLRMYTRWAEQHGY
                     QVETLDYQAGDEAGIKSVTLLIKGHNAFGYLKSEKGVHRLVRISPFDSAKRRHTSFCS
                     VDVMPELDETIDIEINPDDLKIDTYRASGAGGQHINKTESAVRITHLPTGTVVASQAQ
                     RSQLKNREQAMGMLKAKLYQLEVEKKEQEAAALRGEQKEIGWGSQIRSYVFHPYSMVK
                     DHRTNVETGNVQAVMDGDLDLFIDGYLKMHLQ"
     gene            14272..14958
                     /gene="ftsE"
                     /locus_tag="ACG8LA_001717"
     CDS             14272..14958
                     /gene="ftsE"
                     /locus_tag="ACG8LA_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005237293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HFQ0204016.1"
                     /translation="MIEMKDVMKKYSNGTTAIRNLSIVIEQGEFVYVVGPSGAGKSTF
                     IKLMYREEKASKGTLNVAGHDLIAIKNREVPYLRREIGVVFQDYKLLPRKTVYENVAY
                     AMQVIGRKPRDIKKRVMEVLDLVGLKHKVRVFPSELSGGEQQRVSIARAIVNTPKVLI
                     ADEPTGNLDPENSWEIMKLLDRINAQGTTVVMATHNSTIVNTIRHRVIAIENGRIIRD
                     QAEGEYGYDD"
     gene            14951..15835
                     /gene="ftsX"
                     /locus_tag="ACG8LA_001718"
     CDS             14951..15835
                     /gene="ftsX"
                     /locus_tag="ACG8LA_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010749773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="permease-like cell division protein FtsX"
                     /protein_id="HFQ0204017.1"
                     /translation="MIRTFFRHLLESIKSLKRNGWMTVASVSAVTITLTLVGVFMAVI
                     MNATKLAQDIEGNVDVSVFVDIGTKDEEMKKLEKELNDLDHVKKVEFSSKEQELKKIQ
                     NEMGDSWKLFEGDNNPLYDVYVVSATDPSYTKQVAEKAADLKNVSRSDYGGASSDRIF
                     QIAGAVRTWGLVAAALLLFVAMFLISNTIRITILSRQREIQIMRLVGAKNGYIRWPFF
                     LEGGWIGLIGAILPILIITFGYAWFYQLINPSLLRSHYSLIHPENIVWKINLLMVGIG
                     VIIGSLGSIISMRRFLKF"
     gene            15987..17435
                     /gene="cls"
                     /locus_tag="ACG8LA_001719"
     CDS             15987..17435
                     /gene="cls"
                     /locus_tag="ACG8LA_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008808 - cardiolipin synthase activity
                     [Evidence IEA];
                     GO_function: GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA];
                     GO_process: GO:0032049 - cardiolipin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HFQ0204018.1"
                     /translation="MKIIVDNFFTILLIMNILLSFIIVFRERKETAQTWAWLLVLMFI
                     PVVGFILYIFLGRGISKEKIFDLKIQGKIGKNLEIEEDKQALMRGLYPHPPTGQVDVK
                     QLIYMLTVFESTLYTTKNEITLFTDGREKFDALIEDIKQAEDHIHFQYYIYRSDTLGE
                     EVREALTEAARRGVKVRVLLDAWGSTQVSSSFFQNLKKAGGEVAFFFPLFVPYINPRI
                     NYRNHRKIVVIDGKIGYTGGFNVGNEYLGLVKKFGYWRDNHLRIYGEAVYTLQNRFLM
                     DWNSQHTKEVGYSPEFFPTIHSTGDMAVQIVTSGPDTEHEQIKMTYLKMISLAKREIL
                     IQTPYYIPDGSIHEALKLALLSGVKVHIQIPNKPDHLLVYWATYSFAAELIEYGARIE
                     TYENGFIHAKTMIIDGGIVSVGSANIDVRSFRLDFEVNTLIYDERMASRVRKAFFEDS
                     KISTHLTKEVYENRGMMIKMKEGLARLISPLL"
     gene            17772..18629
                     /locus_tag="ACG8LA_001720"
     CDS             17772..18629
                     /locus_tag="ACG8LA_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HFQ0204019.1"
                     /translation="MKKLKLFLPIIGLAILLSGCSKWIDRGESITAVGSSALQPLVET
                     VAETYQAENPGKFINVQGGGSGTGLSQVQSGAVDIGNSDLFAEEKSGIDASALVDHRV
                     AVVGITPIVNKDIGVKDISMENLKKLFTGEIKNWSEVGGKDQPVVILNRASGSGTRST
                     FEKWVLDGETAVQAQEQDSSGMVRQIVADTPGAISYVAFSYVSDDVDTLNVNGVEPTD
                     ENVTTNKWTIWAYEHMYTRDHPKKLTKEFLDYILSDEVQDNIVGELGYIPVSHMKVER
                     DWQGNIVKE"
     gene            18744..19664
                     /gene="pstC"
                     /locus_tag="ACG8LA_001721"
     CDS             18744..19664
                     /gene="pstC"
                     /locus_tag="ACG8LA_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HFQ0204020.1"
                     /translation="MEDVKKVLLTKSKRSKMEQRGKFISFLCIALIVLVVLSIFYFVA
                     SKGLATFFTDKINVFDFLFGTDWNPSQIGANGKPMVGALPMITGSFIVTFLSAIVATP
                     FAIGAAVFMTEISPKNGTKILQPVIELLVGIPSVVYGFIGLSVIVPFVRSIFGGTGFG
                     ILAGTFVLFVMILPTVTTMTVDALKAVPRHYREASLALGATRWQTIYKVVLRAAVPGI
                     LTAVVFGMARAFGEALAIQMVIGNAALMPTGLTTPASTLTSILTMGIGNTIMGTVENN
                     VLWSLALILLLMSLFFNIVIRMIGKKGELK"
     gene            19664..20548
                     /gene="pstA"
                     /locus_tag="ACG8LA_001722"
     CDS             19664..20548
                     /gene="pstA"
                     /locus_tag="ACG8LA_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010764435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HFQ0204021.1"
                     /translation="MNAKRSDKIATGVLYVVSGIIVLILAALLLYILVRGIPHISWSF
                     LTEPSKAYQEGGGIGIQLFNSIYLLLITMIISFPISLGAGIYLSEYAGKNWLTDVIRT
                     SIEILSSLPSVVVGLFGFLVFVIQFQYGFSIISGALALTVFNLPLLTRTVEESLQAVH
                     YTQREAGLALGLSRWETVIKVVVPEATPGILTGVILSSGRIFGEAAALIYTAGQSAPA
                     LDFTNWNPLSVSSPISIFRQAETLAVHIWKINTEGTMPDGVSVSAGASAVLIIAVLLF
                     NFGARAIGKRLYRKMTSA"
     gene            20563..21369
                     /gene="pstB"
                     /locus_tag="ACG8LA_001723"
     CDS             20563..21369
                     /gene="pstB"
                     /locus_tag="ACG8LA_001723"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002408906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HFQ0204022.1"
                     /translation="MKKYNWNETNVITMPKDKEVALYTNDLHVWYGDNEAIKGVDLEF
                     EKNKITALIGPSGCGKSTYLRSLNRMNDGIANTKITGKIMYKDVDINAPQVDVYEMRK
                     RIGMVFQRPNPFSKSIYDNITFALKQHGEKNKKKLDEIVETSLKQAALWDQVKDSLDK
                     SALALSGGQQQRLCIARAIAMKPDILLLDEPASALDPISTGTVEETLVNLKEDYTIII
                     VTHNMQQAARISDYTAFFYLGKVMEYDKTNKIFTRPKIQATEDYVSGHFG"
     gene            21385..22143
                     /gene="pstB"
                     /locus_tag="ACG8LA_001724"
     CDS             21385..22143
                     /gene="pstB"
                     /locus_tag="ACG8LA_001724"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HFQ0204023.1"
                     /translation="MTKEIISSKDLHLYYGKKEALKGIDLSFNQGEITAMIGPSGCGK
                     STYLRSLNRMNDLIPNVTITGSVLYKDKDIYGPKTDVVELRKEIGMVFQQPNPFPFSI
                     YENVIYGLKLKGEKDKKVLDQVVEESLKAASVWEDVKDKLHKSALSLSGGQQQRVCIA
                     RVLAVNPEIILLDEPTSALDPVSTGKIESMLLELRERYTMIIVTHNMSQASRISDKTA
                     FFLDGHLIEYNDTKKIFMNPEKQETEDYISGRFG"
     gene            22156..22833
                     /gene="phoU"
                     /locus_tag="ACG8LA_001725"
     CDS             22156..22833
                     /gene="phoU"
                     /locus_tag="ACG8LA_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010723432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA];
                     GO_process: GO:0030643 - intracellular phosphate ion
                     homeostasis [Evidence IEA];
                     GO_process: GO:0045936 - negative regulation of phosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HFQ0204024.1"
                     /translation="MLRTQFEEELLNLHNQFYEMGMMVSSAVHKSVRAYIKHDKILAQ
                     EVIENDININNMETRLEKKSFEMIALQQPVTTDLRMIITVMKASSDLERMADHAVSVA
                     KSTIRVKGQTRIPEIEKEISDMSDYVKKMVDNVLVAYVKTDEKDARTIANMDQRVNDY
                     FNRIYNATIKNMQENPETVISGTDYLNVASYLERIGDYVTNICEWIVYLATGKITELN
                     TNHNEIF"
     gene            23397..24089
                     /locus_tag="ACG8LA_001726"
     CDS             23397..24089
                     /locus_tag="ACG8LA_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HFQ0204025.1"
                     /translation="MLLIGGKQGVFALGSLIINIVLLLLLLLLFTKTEGISLLNIAIL
                     FVVIGIIVSILALDGWNRSSIIKISAAVTSVFLAFFICLLTMNHWKDQGLRYEELNYL
                     TRPYRSVFLSSVLIGTAGGTLDTVITVIATLEELTKQQPKISAKQLWLSGRQVGRDVI
                     GSMANILLFVYISGAIPSLLLYLGNQWSFKETVERHLSLELLRVIAGSLGIVLSIPIA
                     VLFFLAVRRLKK"
     gene            24086..24853
                     /locus_tag="ACG8LA_001727"
     CDS             24086..24853
                     /locus_tag="ACG8LA_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HFQ0204026.1"
                     /translation="MNVLIILVGIFAISVLFVGGTQGMYILLGLFINLGIFFLLLFGY
                     HQKWPILVLSIIGFLLIAVVILFFINGYNLKMRAAFASILIFLFCFLLLIPITDFLAI
                     QGFTSIELEELSGLDKTLAIDFRLLTRSLLLISLSGAVLDASVAISSGTFEVYQANPQ
                     MSFNQLRHASFAIAKKILASTVMTLLFAFMGSSLALILWFIDLDISFQQIINEKSFVL
                     EYTMAILTTLAALLVLPLTCVTTAYLFTKKKEHLKME"
     gene            24953..26521
                     /gene="liaX"
                     /locus_tag="ACG8LA_001728"
     CDS             24953..26521
                     /gene="liaX"
                     /locus_tag="ACG8LA_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="daptomycin-sensing surface protein LiaX"
                     /protein_id="HFQ0204027.1"
                     /translation="MKERERILDLVKKGILSTEEGLDLLESMATEKDEKQIKKEADKV
                     TASHKEKDQASQLIDELENGEEKISEPVDPKEKERQDQENLEKILDELATEANKTSAR
                     LDEVNAQFADNKAARNEKQEALMQLNTKEELGELTEEELAQRQTLEAEIKELEATGDT
                     LLEEQLKLEAELKDIRKNQWSEKKETFTDKFELPDDWKDQATDTLNQVGEKMSEAGSQ
                     LGKFLKKTFQTVSETVNDNMEWKDVSLRVPGIATTKFEHEFYYEAPAASILDIKAANG
                     NVTLKTWDSDDVKVEAKIKLYGKMGAEPFEAFSERSQIEVNEDHISFQIPNKRVRADL
                     VFYLPKRVYDHAAIKLLNGNIMIETLEAKDIYTKSTNGNIIVNQLTATMLEVEGVNGN
                     IDIRNGNILDSIIETVNGTVTFGATPENLSVSLVNGDVRLTIKEDNLKKVEASSVNGN
                     VKVALPDSIGLEGHAKTSLGSINSRLSNYEVVREKKERTNQMLQFRRVSDDEIAQVQL
                     STTTGSIYLKDTDK"
     gene            26697..27005
                     /locus_tag="ACG8LA_001729"
     CDS             26697..27005
                     /locus_tag="ACG8LA_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0080135 - regulation of cellular response
                     to stress [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HFQ0204028.1"
                     /translation="MMKKKLTKSNKNVVLTGTLAGIGEYIGIDPTVIRVLYVFLSLVA
                     FGSPIILYILLALIIPSARSARTNYGHNNAYYEKNNYREQTKKRKEAEKIDDDEWSDF
                     "
     gene            27005..27355
                     /locus_tag="ACG8LA_001730"
     CDS             27005..27355
                     /locus_tag="ACG8LA_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HFQ0204029.1"
                     /translation="MSYFQRILVNTLTFISLAVLFPAMVHVSSIWTAVLASFVLSVLN
                     MFVKPILTILSLPFTLVTLGLFTFVINAAILKMTSFFVGAEHFSFSSFGAALFVAILM
                     SLVNVIVSEHNSRK"
BASE COUNT         9041 a         4670 c         5938 g         7739 t
ORIGIN      
        1 ttttgtctca gtcccttttt ttgcatattt ttagcattta tttcctaaaa aatgtaaggg
       61 gattcctata tttttaagta tacttgtttt tccttttata cattttatgg tattatcatt
      121 ttattagtta ttataaaaca atcgttagaa aggacgtcat tatgcaagta tacggaattg
      181 atgcggtgct tcgaatcgtg agtcatttgg cgtttatcta cttagccttc tggtctttac
      241 gttcgttacg cattgaaact tttttcagac caatgcataa tacgcaaatt agaatggcaa
      301 tcgtactttt ttcaattttt ttagggtaca ctgcaagtaa ttttttctta gaagttatcg
      361 ctttatgccg aaatcttttc gttagcctgt aaattttaaa aaaaggtact attttaaaag
      421 caaggatgtt ataatagaaa agattttgag taagtgtatg ctcattggaa ttttttggag
      481 ggaacaacat ggaagagatc atcgtaagag gtggcaatca attaaatgga acagtaagaa
      541 ttgaaggagc taaaaatgct gttttgccta ttttagctgc tagtttgtta gcagaagaag
      601 gtattacgac attagacaac gttccgattc tttctgatgt cttcactatg aatcaagtga
      661 ttcgtcactt aaacgtagat gtagattttg atgaacaaaa gaatcaagta acaatcgatg
      721 cttcaagaca attagaaatc gaagcgcctt atgagtatgt tagtcaaatg cgtgcttcaa
      781 tcgttgtgat gggtccgcta cttgccagaa atggacatgc aaaagtagct atgcctggtg
      841 gatgtgcgat tggtaaacga ccaatcgatt tgcatttaaa aggatttcaa gctttaggag
      901 caaaaattat tcaaaaaaac ggctatatcg aagcaattgc ggatgaattg atcggtaaca
      961 cgatttattt agatttccct agtgtaggtg ctactcaaaa tatcatgatg gctgccgtaa
     1021 aagcaaaagg aacaaccatc attgaaaacg tagctcgcga accagaaatc gttgatttag
     1081 caaacatttt gaataaaatg ggcgctcaag tctatggagc tggtactgaa acaatgcgta
     1141 ttgaaggcgt ggatcattta catgcagtca accactcaat cgtacaagat cgtatcgaag
     1201 caggtacctt tatggttgct gctgcaatga cacaaggcaa tgtgctgatt gcagatgcta
     1261 tctctgaaca taaccgccca ttgatttcta aattgatcga aatgggtgca gaaatcattg
     1321 aagaagaagg cggagtccgt gtcatcggac caaaacatat cttacctaca gatgtaaaaa
     1381 cgatgcctca tcctggtttc cctacagata tgcaagctca aatgacagct atccaattag
     1441 ttgcagaagg tacaagtgta gtgactgaaa cagtgtttga aaatcgtttc caacatttag
     1501 aagagatgcg ccgtatgaac gctcatgtca aaatcgacgg aaatgtagca atcatggatg
     1561 gaaaccatga attgcaaggt gcagaagtat atgcaacaga cttgcgggca gcagcagcat
     1621 tagttttagc tggcttgaaa gcaaatggaa tcacacgtgt gcgtaacttg aattatctag
     1681 accgtggata ttataatttc catatcaaac tacagcaatt aggtgcagac gttgaacgtg
     1741 tagacatgga tcaaacttct gctgaaaaaa cagcacaaac gattgcttaa ggaagtggct
     1801 gaatgagtaa ccaacgatat atcttattaa ctttgataaa gattttagtg gtgatcttat
     1861 tgcttatcct tctttttgtg gccggaacga tgatcggata tggtgtcatc ggtggcggca
     1921 atccatttaa agtattccag ccaagtttgt ggattcatat tcgagacttt tttcattgat
     1981 aaataagaat cacagtggtt ctagtcgata tgaagtgagc catgaagcag aacatgacaa
     2041 aagaaaacag aagggaacgt tgacgttagt cgcgatccct ttttttagta aaagaaaaga
     2101 aggaatctaa ttgatgaaga agatattgat ttatttagtt agaggatatc agcgctttat
     2161 ttcgcctgca tttccaccta gctgccgtta ttacccaacc tgttccaatt atatgataaa
     2221 agcaattcaa acccatggtg cactaaaagg gacggtaatg gggactgcac ggatcttacg
     2281 ctgtcatcct tttgtcaaag gcggtatcga ttatgtacca ttgacattcc aattaacgcg
     2341 aaataagaaa gataaaaaag aaccagatta taaaaaggtt gtgaaaaata cgagtagcac
     2401 tgagcgataa agaaacaatt tggaaaatag cttcttatat tttgcaaaat tgtgagttat
     2461 tgccgaagtg ttggattttg aacaccgtca aaaaaaggtt gtgaaaaata cgggtagcac
     2521 tgagcgataa agaaaaagag gaaaattatt gtcaaagtaa caactccgca actacttata
     2581 tgggggacaa aaaatgatcg aagaactaaa caagaaagat ttaccatggt ccttgttatt
     2641 agatgcagat cctgataaag aaaaagttca agtatatgtt tccagaggga gtggctggat
     2701 atggaaagaa aaagaaaaaa caataggtgt actgatctat gtggcaaggg aaaaagaata
     2761 cgaaatcgtc aatgtagcag tagccccaac gtatcaagga aaggggattg gcggaaaatt
     2821 acttgagaca gcttttcaga agctttcaca actcgcttcc agtcaaactc agatcatcat
     2881 acgaaccggc agtactagca gtgcggcgtt acatctctat caaaaaatgg gctatgtgga
     2941 gattggtcga gtcaaagact attttatcca tcattactct gagcccattt ttgaaaatgg
     3001 agatcaatta agggatcaag taattttagc aattcactta cctaaaaata gctttaacta
     3061 ataaactttc aattcgagaa aatgctttca aatgctaaat agatacatta caatagcttt
     3121 agcaaacaaa aaggagaata tttttatggg aatattagtt tttgattttg gtggatcggc
     3181 tgtcaaatat ggttgttggg atggcaaaga gattaaaggt aagggacaat ttgcaacgcc
     3241 tgaatcttgg gaagaaatga aagcgcaatt atttcaagtt tataaaaaaa tactcgtttc
     3301 ttttgaagtc gaaggaattg gaatcagctc tcctggagta gtgaataatg agaaacaggt
     3361 gattgaggga atcagtgcga ttccttatat tcatggattt aatattttcc gagatttgga
     3421 aactctgttt caactcccag taacgattga aaatgacgcc aactgtgccg gaatggctga
     3481 attttatgaa ggtgctgccc gtgattatca agatgttgct tttgttgtgg caggaactgg
     3541 gattggcggg gcgttgttca cgaaaggaca aatcaataaa ggggcacatc tttatggtgg
     3601 agaatttggg ttgatgttct taaatggcga taagacattc agtaaacttg gtacagcggt
     3661 acagatggct tggcgttatt gtgaacgcaa aggtctcgat aaaaattctt ataccggaaa
     3721 agatgtcttt gaattagcag aaactggaga tgcaatagca aaagaagaag ttgagagttt
     3781 ttatacgtat cttacaaagg gattattcag tattcaattt tcgtttgatc cagaagtgat
     3841 cgtattaggc ggcggtgttt ctgcaaaaga agggctcatt gatgagatca aaagccgaat
     3901 gaagaagctg acagaacaat tcgatctgca tgatttcgaa ccgcagattt tattatgtga
     3961 atacagaaac gatgctaatc ttgtaggtgc agcagcaaac tatctcgctg tacgtcaagg
     4021 ggagaattaa gagctttaga gaaggtgcag cttgcataaa agaagtgaat gaaatgaata
     4081 ggagattttt acctaaggaa tgttttattt gctgcagtat gataaaatat ctgagaggtg
     4141 aaaatgatgt caaaaaaaaa taaagatgtt gaagtgcgta tagaagaagt gaaaaaagat
     4201 atcaaaggta agaattatga agtcactcag ttatttatag ggaaaaaaat gattggtgag
     4261 atcttagcct atgggccaaa agaatatgaa attttctttg gtgaagaaga ttttggaaaa
     4321 gaaaaaagtc ttgaaaatgc gatagaaaca gtgattcgac actggaatct gcacgaataa
     4381 aaaaatatca aaaaaacttt caataaaggg ttgcaaaaat ctggaaaatt aggtattata
     4441 actaagtcag gttgatacaa acctttcgga ggagtagcga agtggctaaa cgcgacggac
     4501 tgtaaatccg ttccttaggg ttcagtggtt cgaatccact ctcctccatt tcattggggt
     4561 atagccaagc ggtaaggcaa gggactttga ctccctcatg cgttggttcg aatccagcta
     4621 ccccagtata ccacaatcgt aagctctcgt tagttcgaga gctctttttt ttgctttgct
     4681 accttgttcc ttgaagattc tgctgattta agatagagtt aagttaacta caagaattgg
     4741 agggatccac atgaaatgga aagaaaaagt agacgaagca gctgaaaagt tatatgattt
     4801 ggtcaaatca gaaaaataca atattgaagt gaatattccg aaaaaaggcg gaaaagcggt
     4861 ccaggtaaaa tcaaaacgcc caacgaatca tacaaaaaaa tggatggcta aaaaccgcta
     4921 ataataacaa aagatccata agtcggcatt ttcatcgatt ttagggtctt ttgttatttt
     4981 ctaggttgaa catatctaaa aaattgtttc tgacaatagg agtaggaaga acgatgtgtg
     5041 tctaaatcct ctgttgatgg atagaaacct ttatcttttt cagttgtgaa tcaggtatat
     5101 accagttata atagaagaaa cgaaaggacg ggtgtacgtt atgtcgaatc aattacctgt
     5161 atatatacag attcatgacc aattaaaaaa tgaaatcgaa caaggtatat ggaaagtcgg
     5221 agaccgtctt ccttcagaaa gagaattagc agtgaaattc aatgtcagcc gtatgacgtt
     5281 gagacaagca attcaaaact tggcagatga aggaatctta gaaagaaaga tcggttcggg
     5341 tacatatgtt gcgcgagaaa aagtacaaga aaaaatgtct ggtgcaacaa gttttacaga
     5401 aattatggaa tcgcaaaatc gagtaccgtc tagtcggaca atctcttatt tcttgacttc
     5461 gccaagctca agtgaaatgg aaaaactaaa cttgagtaaa gatgacacga tcttgcgaat
     5521 ggaacgtatt cgtttcgcag atgatgtccc tatttgtttt gaagttgcca gtgtgccaca
     5581 aaagctgatc gatggctaca gcaaagcaga gattactgaa tcgttgtatc gcacgctaga
     5641 agaaaaaggc gggaaaaaga tcggtccagc gaatcaaacg attactgctg tgttggcttc
     5701 tgagaaaatt gctgactatt tagaggtaaa acgaggagat gcagttcttc gtttgcgcca
     5761 gatttcttat tttgaagacg gtacgccgtt tgagtatgtg cgtacgcaat acgtaggaaa
     5821 tcgttttgag ttttatttgg aaaaataaaa aacaggtgat ccctgattcc ttacttagaa
     5881 ataaaagaga atcagaatca cctgttttta tatatgatca gttaccagtt gctcgtgata
     5941 agaaacagga ccctcttcaa attggacttg tccgttcagc agctcaatga tggattcttt
     6001 aaagtggtca gcactttttt catctacagc acagatgacg ctaacttgat cagtatattg
     6061 gatttctttt ataaaaaaat gttggagttc aagataattc tgtaattttc ctagttgcgg
     6121 atacgtgatc atcacagaga tctcctgttg caaggtacct tctacgattc caatgtcaga
     6181 caatgcttga gagacagcat gagtgtatgc tcgtattaat ccgcctgtgc cgagtttcgt
     6241 tcctccaaaa tatcgagtga ctactgcagc tacattgatc agttgatttt ttttgaggac
     6301 ttccaacatc ggtacgccag ccgttccact tggttctcca tcatcgctgc ttcgctggat
     6361 ttcatttttt tctccaatga tgaaggcgct gcagttatgg ttcgctttcc aatgttcttt
     6421 ttttatttct tgaatgaaac tttttgcttg gtcctctgat tctattcgtc taagagaaca
     6481 gataaagcgt gattttttga tctcaatctc actttgtcca ttttctttta ttgtacgata
     6541 gcgctcgatc atcttgtcac ctcttttttt cattttcttt attcagtata aataaagttc
     6601 taggttgttt caacactgta acggttgcgc aatcgctgta gtatgcgata ataaagacaa
     6661 aggtaggtgg atctggggat gcaggaacga atgaaaaagt acgatgcaat tacgcattat
     6721 ttgaagaaca atggcggctc tcaagtaacg ttgaccttta cccaatttga cgaactgctg
     6781 tttcccagta acggacttcc caaaacagca agggaaagta cagattggtg ggcaaatgat
     6841 tataaacacc ctgaaaaagg tgcctatggc tggataaatg caggctatga agtagttgtc
     6901 atcaatttgg acaaagaata tgtcgtgttc aataaattag tgaaatctag ttggctattt
     6961 gattaaataa accgcgttta gaaaacgttg acaaatttct ttctttttat ataatagagt
     7021 aacagacgcg aagaaaacgt ttgcgtagtt tgttttaaaa aggagagaaa agtatggcta
     7081 aaaaaacaat catgcttgta tgttcggctg gtatgagcac aagtttacta gtaacaaaaa
     7141 tgcaaaaagc tgctgaagca aaaggaatcg actcggatat tttcgctgtg tccgcttctg
     7201 acgcagataa caatcttgca aataaagatg tagatgtact gttattagga cctcaagttc
     7261 gctttatgaa agctgatttt gaaaaacgtc tggaaccaaa aggcattcct ttagacgtca
     7321 tcaatatggc tgattatggt atgatgaatg gcgaaaaagt gttagatcaa gcaatcacgc
     7381 tcataggtga ataaatagaa cagtataact atcgaacaag cgatccaaaa aatagatcgc
     7441 ttgttttttc gtatattttt ttagggcgaa taatatgaat catttttggg gtagaaggct
     7501 tctgacgaga gatattaaag caatagactg tgaggaggta aatttaccaa attatgagaa
     7561 gatcgcagca gtggaacgtt tgggcaactg gattctttgt catcgctgtg gaatgaggac
     7621 gtccgtcatt gatggacagc ttgcagatta cggttatttt tgtacacatt gtctatattt
     7681 agggcgatgc gacactcaac aagatttata tttgtttgat cagcctgaag caaaacctcg
     7741 agaagtcgtc tttttttgga caggacagct tactgaaaaa caaacggaaa tcgcaaagag
     7801 aatactttgc cattcagaaa aaagacatca tcttatttgg gctgtaacag gtgcagggaa
     7861 aacagagatg ctttatccta ttttagtgga aactttaaaa gctggaggaa gagtagcgat
     7921 ttgtacaccg cgagtcgatg tttgtaatga attgttttta cgctatcgtt atgtttttcc
     7981 agaagaaaaa atcacgttgc tccatgggaa tacagcaacg gcttatacct ttacttcttt
     8041 tgttatctgt acgattcatc agctataccg tttttatcgg tcctttgatt taatagtgat
     8101 cgatgagatc gatgcgtttc cttataacgg ggatgcagga ttagctcatg ctgtgcaaac
     8161 agcgattaaa ccagacggac gattcatcta cttaagtgcc acacctgata aaaagttact
     8221 aaaggaaatc aagcagacgt ttgacatcca caaacttgct ttgcgctttc atcggcgttt
     8281 acttcctgaa cccgtcttgg ttttcatgaa taattggcga caaaaatgca agaacaagaa
     8341 gaagataaaa tctttggtgc ggatcattca tcaattaatt aaagaaaacc atatcctttt
     8401 attttgtcca agtatcacga tgatgcatcg tttgaaagcc acacttcaag aggctcttcc
     8461 gagatatgag atcacagatg tttcttcaag agacaatcag cgggcggaaa aagtccagaa
     8521 aatgcgagaa gcaaaatatg acatactgtt aaccacgatg atccttgaac gtggagtcac
     8581 atttgaaaga atatccgtta tcgttttagg agcggatcat ccggttttta ctaaatcttc
     8641 tttggtacaa atcgcaggaa gagccgatcg taaagggcct tatacgaaca gtcaagtata
     8701 ctttttctat gaagaaaaaa ctgcagctat tcgaaaagct tgtcaggaaa tcaaagaaat
     8761 gaatgaagaa gggaagaaga tgctgtgagg tgcagttgct gcagtaaaga tatcgtccaa
     8821 aatttaacat tcagcgagat tattggtgtt tcgaaataca gattacctca gacttgttca
     8881 gtttgtcgcg cacaatttca tttattggaa acaagaggct gttctggctg tcaaaaacca
     8941 atccatttca atctagagag tacgaaaaag aaagtaaagt ctattcccgt ttactgcagt
     9001 gactgtcaag aatggaagaa gaaatatccg acctatgatt ttcagcaccg tgcctttttt
     9061 gtgtacgatg aaaatatgaa ggcctggctc aatcaataca agtttatggg agatatccga
     9121 ctagcaggca cctttgcata taaatggacg cagataaaaa aagaataccc gacatacatc
     9181 tattgtccaa tacctttatc tgaaaaaagg cgaacagaaa gaggattcaa tcaagtaagc
     9241 gagatgttga aagcagcaag aattcctttt cagatgctac tcaaaagaga gaagcatctg
     9301 ctggctcaag caaaaaacac gcgaaaggaa agattggaga tgcctcaacc ttttgaactt
     9361 gcagtcacct tttctaagat acaaaataaa aaaatattga ttattgatga tgtctataca
     9421 acaggacaga ctcttttcca cgcagcagat tgtttgcagg tcgcacagcc gaaaatcatc
     9481 cgaaccattt ctttagcaag atgaattaga tgtggaaatt tgatagcgat ttaatttgca
     9541 aataacctag agttcgatat aatagaatta agaagaggga aagagtggtc cttctccttc
     9601 ttgattgtgg tagacgaaag gggtaatttt tatgtttaga tataatgtac gcggcgaaaa
     9661 tatcgaagta actgaagcga ttcgcgacta cgttgagaaa aaagtaggca aactagaacg
     9721 ctatttcagt gacgcacccg atgcaacggc gcatgtgaac ttaaaagttt atacagaaaa
     9781 aacagcaaaa gtggaagtaa cgatcccatt accttatctt gtattacgtg ccgaagaaac
     9841 ttctccagat ttatacgcaa gtatcgattt ggttgttgac aaattggaac gccaaatccg
     9901 caaattcaaa acaaaaatta atcgtaaatc ccgtgaaacg ggcatgaata ctgcagatgc
     9961 tactgcttta ttcaatgaag aggacgaaaa cgaaaatgat tctgaattag atatcgtacg
    10021 tacgaaacgc ctttcattga aaccaatgga tagtgaagaa gcagtcttac aaatgaacat
    10081 gctgggacat aacttcttta tttttgaaga tgcagaaaca aatggtacaa gtatcgttta
    10141 ccgccgtaaa gatggaaaat acggactgat tgaaacagac tgatcagcct tacttaaata
    10201 acaacgaaaa cttgcagcag ctactgacag ctgccgcaag tttttttgag tttcctcctc
    10261 ttttagatga aatatgaata aattatgaag ttcttacttt aatacgctta agatatttca
    10321 attatctata actaatgata aaatgaaaag taaagtctac atagtctgga taatacacag
    10381 aaggaaaagg agattacaca acgcatggcc aatttgattc gttcacttat cgaaaacgat
    10441 aagaaagaac taaaacgttt agatagcatt gcaaaaaaag ttgaagcata cgctgaccaa
    10501 atggcagcat taactgatga acaattacag gcaaaaactg ctgaattcaa gggcagatac
    10561 caaaaaggag aaacattaga tcaattactt ccggaagctt ttgcagtcgt ccgagaagca
    10621 gcaaaacgtg tattggggtt atatccatac cacgtacaat taatgggtgg gatcgtgctt
    10681 cacgatggga atatccctga aatgcgtact ggtgaaggta aaaccttgac tgcaacgatg
    10741 ccggtgtatc tgaatgcgtt gactggcgaa ggggtccacg tagttaccgt caatgaatat
    10801 ttagcaaccc gtgactcgac ggaaatgggc gagctttata atttcttagg attgacagtt
    10861 gggttgaata tcaactcaaa atcttcggat gaaaaacgcg aggcttataa ttgcgatatc
    10921 acttatagca cgaataatga attaggattt gactatttga gagacaacat ggtcgtttac
    10981 cgtcatcaaa tggtacaacg tccgctgaat tatgccattg tcgatgaagt tgactcgatc
    11041 ttgattgatg aagcgagaac gccgctgatc atttcagggc aagcagaaaa atcaacagct
    11101 ttatatacaa gagcagacaa cttcgtgaaa cgtttgaaag aagaagaaga ttataaaatc
    11161 gatatacaat caaaaacaat cagtttaact gaagcaggga tcgaaaaagc tgaagaaaca
    11221 ttcggtttgg acaacttata tgacattgaa aatactgcat tgacccatca cttggatcaa
    11281 gcattgagag ccaactacat catgctttta gacatcgatt atgttgttca agatggaaaa
    11341 gtattgattg ttgaccaatt tacgggtcgg atcatggatg gacgccgtta ttcagatggt
    11401 cttcatcaag cgatcgaagc taaagaaggc gtagagatcg aagacgaaac gaaaacgatg
    11461 gcgacgatca ctttccagaa ctatttccgt atgtacaaga aacttgcggg gatgactggt
    11521 acagctaaga cagaagaaga agagttcaga gagatttata atattcaagt ataccagatt
    11581 ccgacaaacc gtccggtcat ccgtgacgat cgaccagatt tgctttaccc aacattacaa
    11641 agcaagttcc atgctgtcgt acaagatatc aaagatcgct accgcaaagg acagcctgtc
    11701 ttagtcggaa ctgttgcagt tgaaacatct gagttattat cagatatgct gaatcaagaa
    11761 cgtattcctc atgaagtact gaatgcgaaa aatcacttta aagaagcaga aatcatcatg
    11821 aatgcgggtc aaaaaggtgc agtgacgatt gctaccaaca tggctggtcg gggaacagat
    11881 atcaagctag ggcttggcgt aagagaactt ggtggcctag cagttatcgg gacagaacga
    11941 catgaatctc gtcgtatcga taaccagctt cgaggacgtg caggacgtca aggagaccct
    12001 ggtatgtcac aattctactt gtctttagaa gatgatttga tgaaacgatt cggttcagaa
    12061 cgaatcaaag ctttcttaga tcgaatgaag atcggtgacg aagatgctgt gatccaaagc
    12121 aagatgctga cgaaacaagt agaagctgca caaaaacgcg tagaaggaaa caactacgac
    12181 acacgtaaga acgtcttgca atacgatgac gtgatgcgtg agcaacgtga agtaatctat
    12241 aaacagcgtc aagaagtgat catggaagaa aaaagcttat ctaaaccact gatgaatatg
    12301 gtcaaacgga caatcagtcg tgtggtagat gcgcatacgc aattagaaaa agaaaattgg
    12361 aatttggaaa gtatcgtcga ttttgctggc agcacgcttg tccatgaaga cagtatttcc
    12421 cttacagata tcgaaggaaa aacctctcaa gaaatcaaag aatatctaaa cgaacgagca
    12481 caagaagtat tcaataccaa agcagctcaa ttgaacggac cagagcaact gcttgaattt
    12541 gaaaaagtcg tgatcttacg tgtcgtggac tctaaatgga cagatcatat tgatgcaatg
    12601 gaccaattac gtcagtcaat cggcttgcgt gcctatggtc aaaacaatcc attagtcgaa
    12661 taccaaacag aaggttataa gatgttcgaa gatatggtag gtgccattga atatgaagtc
    12721 actcgtatct tcatgaaagc tgagatccgt caaaacgtac aacgtgagca agtttctcaa
    12781 ggaacagctt ctcactcaga agatggagat gccaaagaaa acagtaatac tagcgcgaaa
    12841 aaacaaccaa tccatgtgaa caaggttggt agaaatgatc cttgtccttg tggaagcggg
    12901 aaaaaatata agaactgtca cggaaaagat gcaaactaat ttctgacagc aggattggtg
    12961 agacaaattc ttttttaaag aatttgtctc accttctttc tgttatttga cgattctgtt
    13021 agactagata taataaaaaa agtatagtga aagaaggaaa aaaacatgga aatatccgaa
    13081 attcgaaatc tcctgacaga aatgcaggaa aaggtcacaa gcttcaggag gtctctttga
    13141 cttagaccag ctggaagaag acattgcgga agcagaagca aaaatggctg aacctggttt
    13201 ttgggatgat agcgaagctg ctcaaaaagt gatcagtgaa aacaatgcaa ataaagaaac
    13261 ttatgatcaa ttccattctc ttgctgaaga actggaagaa atcgaattga tggtggagat
    13321 gttgcaggaa gaacctgatg cagtaatgca agaagaagca gaagcacgta tcaatgcgct
    13381 agatgaaaaa atgaatacgt atgaattatc tatgttgtta gatggtcctt atgatcgaaa
    13441 caacgccatc gtcgaattgc atccaggggc tggcggaacg gagtcccaag actggggcag
    13501 catgctttta cgcatgtata cacgctgggc agagcagcat gggtatcaag tagagacact
    13561 agattatcaa gcaggcgatg aagcaggaat caagagtgtg accctactga tcaaaggaca
    13621 caacgcattt ggctatctga aatcagaaaa aggtgttcat cgccttgtac gtatctcgcc
    13681 ttttgactca gcaaaacgtc gtcatacttc tttttgttcg gtagatgtga tgccagagct
    13741 tgatgaaacg atcgatatag aaatcaatcc agatgatttg aagatcgaca catatcgggc
    13801 gagtggtgca ggtggtcagc acatcaataa gacagaatcc gctgtacgaa tcactcactt
    13861 gcctacagga acagtagtag cgagtcaggc acaacgttca caattgaaaa accgggaaca
    13921 agcgatgggg atgctgaaag ctaagcttta ccaattagaa gtggaaaaga aagaacaaga
    13981 agcagctgca ctgagaggag aacaaaaaga aatcggctgg ggatcacaga tccgttctta
    14041 tgttttccat ccatattcta tggtaaaaga ccatcggaca aacgtagaga caggaaatgt
    14101 ccaagctgtt atggacggag atcttgattt atttattgac ggctatttga aaatgcatct
    14161 gcaataagag ccctttgtta aattgaaata aaattgtaag attttgcaag caagttgaaa
    14221 cattgccatg ctataatagc taaagactga aaaagatatg gagagaacgc catgattgaa
    14281 atgaaggatg taatgaagaa gtactcaaac ggtaccactg ctatccgcaa tctctcgatt
    14341 gtcatcgaac aaggagagtt tgtgtatgtt gttggtccgt ctggagctgg taaatctaca
    14401 ttcatcaaat tgatgtatcg agaagaaaaa gcttcaaaag gaactttgaa cgtcgcaggt
    14461 catgatctaa tagccatcaa aaaccgcgaa gttccttatc tacgcagaga aatcggcgtg
    14521 gtgttccaag actataaatt attaccaaga aaaacagtat atgaaaatgt tgcgtacgcc
    14581 atgcaagtta tcggcagaaa acctcgggat atcaaaaaac gagtaatgga agtgctggat
    14641 cttgttggtt tgaaacacaa agtccgagtc tttcctagcg aattatctgg tggggaacaa
    14701 caacgtgttt ctattgcccg agcaatcgta aatacaccta aagtacttat cgcggatgaa
    14761 ccgacaggga atctagatcc ggaaaactca tgggaaatca tgaaactatt agatcggatc
    14821 aatgcacaag gaacaactgt cgtgatggct acacataaca gtacgatcgt aaatacgatt
    14881 cgacaccgag taattgctat cgaaaacggc cgcattattc gagaccaagc ggaaggggaa
    14941 tatggatacg atgattagaa cctttttccg ccatttatta gaaagtatca agagtttgaa
    15001 acgtaacggc tggatgacag tagcttcggt cagtgcggta acgatcacgt tgactttagt
    15061 tggtgtgttc atggcggtca tcatgaacgc aaccaaacta gcacaagata tagaaggaaa
    15121 cgtggatgta tctgtgttcg tagacattgg tacaaaagac gaagagatga aaaaattaga
    15181 aaaagaatta aatgacttag atcatgtcaa aaaagtcgaa ttttcaagca aagaacagga
    15241 attgaagaaa atccaaaacg aaatgggcga ttcttggaaa ttgtttgaag gggataataa
    15301 cccgttatat gatgtatacg tagtaagtgc taccgatcct tcttatacaa aacaagtagc
    15361 agaaaaagcg gcagatttga agaatgtttc ccgttctgat tacggtgggg cttcctcaga
    15421 tcggattttc caaattgctg gtgcagttcg aacatgggga ttagttgcgg cggcattgct
    15481 gctgtttgta gcaatgtttc tcatttctaa cacgattcgg atcacgattt tatctagaca
    15541 gcgtgaaatt caaatcatgc gtttagtagg ggcaaaaaat ggatatatcc gctggccatt
    15601 tttccttgaa ggtggttgga tcggcttaat cggtgccatt cttccgatac tgatcattac
    15661 atttggttac gcatggtttt accaattgat caatccgtca ttattacgat ctcattattc
    15721 attgatccat ccagaaaata tcgtttggaa aatcaatctt ttgatggtcg gtattggtgt
    15781 gatcattggt tcactcggct cgatcatctc tatgagacgt ttcttgaaat tctagtgtca
    15841 caagataaat ataatcagaa agttggacga tttcgttcca gctttctttt tttatcagct
    15901 aggtggagta aatggggcgg cttttttctc tttactttaa aaaacaactt gggtattctt
    15961 aagttggtag aaaaagaggt gaagccgtga agattatcgt tgacaatttt tttacgatcc
    16021 ttttgattat gaatattttg ctttccttta ttatcgtttt tcgagaaaga aaggaaactg
    16081 cgcaaacatg ggcatggctg ctcgttttga tgttcattcc agttgtagga tttattttat
    16141 atattttttt aggaagaggg atttccaaag agaaaatctt tgatttgaag atccaaggga
    16201 aaatcggtaa gaatctagaa atcgaagaag ataaacaagc attgatgcga gggctttatc
    16261 ctcatccgcc tactggacaa gtagatgtga aacaattgat ctatatgctt actgtatttg
    16321 aaagtacgct ttatacgact aaaaatgaaa tcactttatt tacagatggt cgtgaaaaat
    16381 tcgatgcgct gatcgaggat atcaaacagg cagaagacca tatccatttc caatattata
    16441 tttaccgcag tgatacatta ggtgaagaag ttcgagaggc attgacagag gcagcaagac
    16501 gcggagtaaa agtcagagtc cttcttgatg catggggttc cacacaagtt tcttctagtt
    16561 tttttcagaa tttgaaaaaa gcaggtggag aagtcgcatt tttctttcct ctattcgttc
    16621 cgtatatcaa tcctcgaatc aattatcgca atcatcgtaa aatcgtagtg attgatggga
    16681 aaatcggata tacaggtggg ttcaatgttg gaaacgaata tctaggattg gtaaagaaat
    16741 ttggttattg gcgagacaat catctgcgta tctatggaga agcggtttac accttgcaaa
    16801 accgtttttt gatggactgg aattctcagc atacaaaaga agtaggatat tcaccggaat
    16861 ttttcccgac cattcattct acaggtgata tggctgttca aatcgtgaca agcggaccag
    16921 ataccgaaca tgagcaaatc aaaatgacat atttgaaaat gatttcgtta gccaaacggg
    16981 agatattgat ccaaacgccg tattacatac cggatggatc gattcatgag gcattgaagt
    17041 tggctcttct ctcaggcgta aaagtccata tccaaatacc taacaaacca gatcatcttc
    17101 tcgtttactg ggcaacgtat tctttcgctg cagagctgat cgagtatggg gcaagaatcg
    17161 aaacatatga aaatggattt atccatgcaa agacgatgat tatcgatggc ggcatcgttt
    17221 ccgttggttc agctaatatc gacgttcgct catttagatt ggattttgaa gtcaatacac
    17281 tgatctatga tgaacgaatg gcttctcgcg taagaaaagc attctttgaa gattcaaaga
    17341 tttcgacgca tctcacaaaa gaagtgtatg aaaaccgagg gatgatgatc aagatgaaag
    17401 aaggattagc aagactgatt tcgccgctcc tttaaaatac aaaaaggaca ggagagccat
    17461 caatagatgg aaatctcgcg tccttttttc tcggggccat ttctgagagt acgtcagaaa
    17521 tggagaaagc gtctcgcatg agcgaaatta actttggggt atctcttgtt ttttggggaa
    17581 agcaagaaat aagctaatat atgctattaa aagagacaca tttcaaagcc agtatagcat
    17641 agaaactttt aatgagatag ctttttttgc aattatgaga atttattttg ttatttaatg
    17701 attttgattc gttttcatca agtaatgaaa atgatagaat aaacatactt taggattaaa
    17761 ggagatttct aatgaaaaaa ctaaaattat tcttaccaat aataggatta gctattcttt
    17821 tatcaggctg ttcaaagtgg attgatcgag gagaatccat tactgcagtt ggctcttctg
    17881 ccttacagcc tttagtagaa acggttgctg aaacctacca ggcagaaaat cctggaaaat
    17941 tcatcaatgt acaagggggc ggaagcggaa ctgggttgtc tcaagtacag tcaggagcag
    18001 tcgatatcgg aaattctgat ttgttcgcgg aagaaaaatc agggattgat gcttcggcat
    18061 tagtcgatca tcgagtagca gttgttggaa tcactcctat tgtgaacaag gatattggcg
    18121 taaaagatat cagtatggaa aacctgaaaa aattatttac gggcgagatc aaaaactgga
    18181 gtgaagtcgg tgggaaagat cagccagtag ttatattgaa ccgtgcatca ggaagcggga
    18241 cccgtagtac gtttgaaaaa tgggtattgg acggagaaac agctgttcag gcacaagaac
    18301 aagattcaag cggaatggtg cgccaaatcg ttgcggacac acccggagca atcagctatg
    18361 ttgctttttc ttacgtttcc gatgatgtgg atacgttgaa cgttaacggt gtggaaccaa
    18421 cagatgaaaa tgtgacaacg aacaaatgga cgatttgggc atatgagcat atgtacacaa
    18481 gagaccatcc aaaaaaactg acaaaagaat ttttagacta tatcttatct gatgaagtac
    18541 aagataatat tgtcggagag ctaggctata tccctgtttc acatatgaaa gttgaacgtg
    18601 attggcaagg aaacattgtt aaagagtaat ctttacacaa aatttacaaa cttagctaaa
    18661 cttttacatg ttattaaaac caaattgatg ttcaatttgt acactgagtg agtatgttaa
    18721 acctgattaa gggggagtca tctgtggaag atgtgaaaaa agtattatta acaaaatcaa
    18781 aacgttcaaa aatggaacag cgcggaaaat tcattagttt tttgtgtatc gcgctgatcg
    18841 tgttggttgt attatctatt ttttattttg tcgctagtaa aggattggcc acctttttta
    18901 ctgataagat caatgtattt gattttctgt ttggtacaga ttggaatcca agccaaatag
    18961 gagcaaatgg gaaacccatg gtaggggcat tgcctatgat cacaggttca tttattgtga
    19021 cctttttatc tgctattgtt gccacaccat ttgctattgg agcagcagtg ttcatgacgg
    19081 agatttctcc taaaaacgga acgaagatct tgcaaccggt catcgagcta cttgtaggta
    19141 ttccgtctgt cgtttacgga tttatcggtt tatctgttat cgtgcctttt gtcagaagta
    19201 tctttggcgg gacagggttc ggtatcttag ctggtacatt tgtgttattc gttatgatct
    19261 taccgactgt cacaacgatg actgtggatg cattaaaggc agtgccgcga cactatcggg
    19321 aagcttcatt agcgctaggt gccacaagat ggcaaacaat ctacaaagtg gtgctgcgag
    19381 cagcagtgcc cggaatttta acagcagtcg tttttggtat ggctcgtgcg tttggcgaag
    19441 ccttagctat ccaaatggtt attggtaatg cggcattaat gccaacagga cttactactc
    19501 ctgcttctac attgacgtcc atcttgacaa tgggaatcgg aaatacaatc atgggaacag
    19561 ttgaaaataa tgtgttatgg tcattagcgc tgatcttgct attgatgtca ttattcttta
    19621 atatcgtgat ccgtatgatt gggaagaaag gagagctgaa ataatgaacg caaaacgctc
    19681 agataaaatt gctacaggtg ttctatatgt ggtttcaggg atcatcgtat tgatcttagc
    19741 agctttatta ctttatatct tagttcgagg aataccgcac atttcatggt cattcttgac
    19801 tgaaccttcc aaagcctacc aagaaggcgg tgggatcggg attcaattat ttaactcgat
    19861 ttatttgctt ttgattacca tgatcatcag ttttcctatc tctttaggtg cgggtatcta
    19921 cctttcggaa tatgccggaa aaaactggct gacagacgtg atccgtacgt ctatcgaaat
    19981 cttgagctct ttgccttctg ttgttgtcgg tttattcggt ttcttggttt tcgttattca
    20041 attccagtat ggtttctcaa tcatttctgg tgcattagct ttgaccgtat tcaacttgcc
    20101 tcttttgact cgaacggtcg aggaatcttt acaagcggtc cattacacac aacgagaagc
    20161 tggattggcg ttaggtttgt cacgctggga aacagtgata aaagtggttg ttccagaagc
    20221 gacaccagga attttgactg gtgtgatcct aagttcagga agaatttttg gtgaagctgc
    20281 cgcattgatt tatacagctg gtcaaagcgc gccagcatta gattttacga actggaatcc
    20341 attaagtgtt tctagtccga tcagcatttt ccgccaagct gaaacactgg ctgtccatat
    20401 ttggaaaatc aacacagaag gtacgatgcc tgatggtgtt tctgtttcgg ctggcgcttc
    20461 tgccgtgttg atcattgctg ttttactgtt caacttcggc gctcgtgcga ttggcaaacg
    20521 attataccga aaaatgactt cagcctaagg agaagaagta aaatgaaaaa atataattgg
    20581 aatgaaacaa atgtcattac catgccaaaa gataaggaag ttgcattata tacgaatgat
    20641 ctgcatgttt ggtatggcga caatgaagca atcaagggag tggatctaga attcgaaaaa
    20701 aataagatca ctgcattgat tggtccctct ggctgcggaa aatccacgta tcttcgttct
    20761 ttgaatcgta tgaatgatgg gattgctaat acgaaaatta ctggaaagat tatgtataaa
    20821 gacgtggata tcaatgcgcc tcaagtggat gtttatgaaa tgcgtaaacg gatcggcatg
    20881 gtgttccaac gccccaaccc ttttagcaaa tcgatttatg acaatataac ttttgctttg
    20941 aaacagcatg gtgaaaaaaa caaaaagaaa ttagatgaaa tcgttgaaac aagcttgaaa
    21001 caagcagctt tgtgggatca agtaaaagat agcttggata aaagtgcctt ggctttatct
    21061 ggcggacaac agcaacgttt gtgtatcgct cgtgcaatcg cgatgaaacc cgatatcttg
    21121 ctgttagacg agccggcaag tgccttggat cctatttcga caggaacggt tgaagaaaca
    21181 cttgtaaact tgaaagaaga ctacacgatc attatcgtga cgcataatat gcaacaagca
    21241 gctcgtatca gcgactatac tgcctttttc tatctaggaa aagtaatgga atatgacaaa
    21301 acaaacaaga tatttaccag accaaaaatt caggcaaccg aagattatgt gtccggtcat
    21361 tttggttaag acggaggcct caacatgaca aaagaaatta tctcatccaa agatcttcat
    21421 ctgtattatg gaaagaaaga agcactaaag ggaattgatc taagtttcaa tcaaggtgaa
    21481 atcacagcga tgatcggtcc ttctggttgc gggaaatcta cctatctacg ttcgttgaat
    21541 cgaatgaacg atctgattcc aaatgtaacg atcaccggaa gtgttttata taaagacaaa
    21601 gacatctatg gtccgaaaac agatgttgtt gaactaagaa aagaaatcgg catggtgttc
    21661 caacagccaa atccatttcc tttttctatt tatgaaaatg tcatctatgg attgaagtta
    21721 aaaggtgaaa aagataaaaa agtccttgat caagtagtgg aagaaagtct gaaggcagcg
    21781 tccgtttggg aggatgtgaa agataaactg cataaaagtg ccttgtcttt atccggtggg
    21841 cagcagcagc gtgtatgtat cgcacgtgtt ttggcagtga atcccgaaat catcttattg
    21901 gacgaaccaa caagtgcact tgaccctgtt tctactggga aaatcgaaag tatgctgtta
    21961 gaattaagag agcggtatac gatgatcatc gtgacccata atatgtctca agcttcacgt
    22021 atttcagata agacggcatt ctttttagat ggtcacttga tcgaatacaa cgatacgaag
    22081 aagatattca tgaatccaga aaaacaagag acagaagatt atatttcagg tcgatttgga
    22141 taaggaggaa acggaatgct acgtacacaa tttgaagaag aattgctgaa tctccataat
    22201 cagttctacg aaatggggat gatggtgagc agcgctgtgc acaagtcagt tcgtgcatac
    22261 atcaaacacg ataaaatctt agctcaagaa gttatcgaaa acgatataaa tatcaataat
    22321 atggaaacgc gtttggagaa gaaaagtttt gaaatgattg cattacaaca gccagttaca
    22381 actgacttgc gtatgattat cacggtcatg aaagctagct ctgatttaga acgtatggcc
    22441 gatcatgcgg tgtccgttgc taaatccaca atccgcgtaa aaggacagac gagaataccg
    22501 gaaatcgaaa aagagatctc cgatatgtcc gattacgtga aaaaaatggt ggacaacgtc
    22561 ctagttgcgt atgtcaaaac agacgaaaaa gatgcgcgta caatcgccaa tatggatcaa
    22621 agagtcaatg actatttcaa tcgaatctat aatgcaacca tcaaaaacat gcaagaaaat
    22681 cctgaaacag tcatcagtgg cacagactat ttgaatgttg ccagctatct agaacgaatc
    22741 ggagactatg tgacaaacat ctgtgaatgg atcgtctact tggctacagg gaaaatcact
    22801 gaattaaata cgaaccacaa tgagattttc taaactgaag ttgtgattct gctgtttatt
    22861 taggaaaaga ggttgtgaaa tcagcgtttt gtcctgagta ttagagaaac aaacggtaaa
    22921 atagttcctc atattttgcc gttttttgag ctaataccga aggtcagctg attgaacacc
    22981 gtttattctg gaaaagggtt tgtgacaaaa catgtcacaa acccttttca ttattccaat
    23041 agaaaggata aagaatgcaa aaaaagatta gcatcatcat cactctattt tttatttgta
    23101 tacttgcttc atggtttatt cagcgtcaag ctgctctata tgacgtacct gtcatcgaga
    23161 tcgaaagagt gagaatagaa gaggatcaac aattgattac aggaagattg atgaatacgg
    23221 accaaaaagg agaagtgatt tctttaacgg ctccttatca aaaaaatcaa atcgaaacag
    23281 caaatataac aacaagacaa atctatcttg tccaaatgca tggagatgaa tggcaactag
    23341 tagcaaaaaa aaatgatggc tggctttttt tctttacaag tgtcttcatt ggcaccatgt
    23401 tgcttattgg tggaaaacag ggcgtatttg ctttaggaag tctcatcatc aacatcgttt
    23461 tacttttact tttgttgctc ctctttacca aaacagaagg tatttctctc ttaaatatag
    23521 caatcttatt tgtcgttata gggataatcg ttagtatatt ggcgttagac ggatggaata
    23581 gaagcagtat aatcaaaatt tcggctgcag ttacaagtgt ttttttagca ttttttattt
    23641 gtcttttgac aatgaatcat tggaaagatc aaggactgcg ctatgaagaa ctgaattatc
    23701 tgacacgacc gtatcgttct gtttttcttt ccagcgtgct gattgggaca gctggaggga
    23761 cactcgatac cgtgatcaca gtcattgcga cattagaaga attgaccaag caacaaccga
    23821 aaatatcagc gaaacagtta tggctttcag gaaggcaagt gggccgagat gtgattggtt
    23881 cgatggctaa tatcctttta ttcgtctata tcagcggagc gattccatcg cttctgttat
    23941 atttaggaaa tcaatggtct ttcaaagaaa cggtagaacg acatttatca ttagaacttt
    24001 tacgcgtcat tgctggcagc ttaggaatag tattatcaat ccccatcgcg gtcctctttt
    24061 ttctcgctgt aaggaggtta aaaaaatgaa tgtacttatt atacttgttg ggatttttgc
    24121 aatcagtgtg ctatttgtcg gtggtacgca aggtatgtat attcttttag gattattcat
    24181 taatttagga atctttttcc tattattatt cggctatcat cagaagtggc cgatattggt
    24241 attgtcgatt atagggttcc tattgatcgc tgtggttatc ttatttttta tcaatggtta
    24301 taatctgaaa atgcgagccg cttttgccag tatactgatc tttttgtttt gtttcctact
    24361 attgattcct atcactgatt ttttagcgat ccaaggcttt acttcgatag aactagaaga
    24421 actatctggc ttagataaga cgttagcaat tgattttaga ctacttacga ggtcgttgct
    24481 tctgatcagt cttagcggag ctgttttaga tgcgagtgta gcgatttcta gtggaacatt
    24541 cgaagtatat caggcaaatc cgcaaatgtc ttttaaccaa ttgcgccatg ctagctttgc
    24601 cattgctaaa aaaatattgg catcaacagt gatgacgctt ctttttgcgt ttatggggag
    24661 ttctttagcg ttgattcttt ggtttattga cttagacatt tcttttcagc aaataatcaa
    24721 tgaaaaatca tttgtcttgg aatatacgat ggctattctt accacactgg ccgcactact
    24781 tgtcctgccc ttaacttgcg tgactacagc atatctcttt acaaaaaaga aagaacatct
    24841 caagatggag taaaagttac aacttaagtc ctatgacatt tttactgaat cagtgcataa
    24901 tatggatgta aggaaaagct tgcaaacaat tttgcttaag gaggcaattt ccatgaaaga
    24961 aagagaacgt attttagact tagtgaaaaa aggaatcctt tcgactgaag aaggcttaga
    25021 tttattagaa agcatggcaa ctgaaaaaga cgaaaaacaa atcaaaaaag aagcagacaa
    25081 ggtaactgct agtcataaag aaaaagatca ggcaagtcaa ttgatcgatg aacttgaaaa
    25141 cggtgaagaa aaaatttctg agccagttga tccaaaagaa aaagaaagac aagatcaaga
    25201 aaacttagaa aagatcttag atgaactagc aactgaagcg aataaaactt cggcgcgtct
    25261 agacgaagta aatgctcaat tcgctgacaa taaggcagca cgtaatgaga aacaggaagc
    25321 attgatgcag ctgaatacaa aagaagaatt aggcgagttg acagaagaag aattagcaca
    25381 gcgtcaaacg ttagaagcag aaatcaaaga gttagaagca accggcgata cactattaga
    25441 agaacaattg aagctggaag cagaattaaa agatatccgc aagaatcaat ggtctgagaa
    25501 aaaagaaaca tttacggata agtttgaatt gccagatgat tggaaagatc aagcgacaga
    25561 tacgctgaat caagtaggcg aaaaaatgtc agaagctgga tcacagttag gcaaattctt
    25621 gaagaaaaca ttccaaactg tttcagaaac agtaaatgat aacatggaat ggaaagatgt
    25681 cagcttacgc gtccctggaa ttgcgacaac gaaatttgaa cacgaatttt attatgaagc
    25741 tcctgcagca agtatccttg atatcaaggc agcaaacgga aacgtgacgt taaaaacgtg
    25801 ggacagtgat gatgtgaaag tggaagccaa gatcaaactt tacggaaaaa tgggtgctga
    25861 accatttgaa gcattctctg aacggagcca gatcgaggtc aatgaagatc atatctcctt
    25921 ccaaattcca aataagcgtg tgcgtgcaga ccttgttttc tacttgccta aacgagtata
    25981 cgaccatgca gctatcaaac ttctaaatgg caacatcatg attgagacat tggaagctaa
    26041 agatatttat acaaaatcta cgaatgggaa catcatcgtg aaccaattaa ctgcaacgat
    26101 gctggaagta gaaggtgtaa acggcaatat cgatattcga aacgggaaca tcttagattc
    26161 tattatagaa acagtaaacg gtacagtgac atttggtgcc acaccagaaa acctttctgt
    26221 gtctttagta aatggtgatg tacgtcttac gattaaagaa gataatttga aaaaagtaga
    26281 agcaagttca gtgaacggga atgtcaaagt tgctttacca gatagcatcg gtttggaagg
    26341 acacgctaaa acaagtcttg gaagcattaa cagccgtctg tccaattacg aagtagttcg
    26401 tgagaaaaaa gaacggacaa accaaatgtt gcaattccgt cgtgtttcag atgatgagat
    26461 cgcacaagtg cagctttcaa cgacaacagg aagtatctat ttaaaagata cagataaata
    26521 aagaggttgt gaaagagatg ttcagccttg agcaataaga agcgattttt taaaatagct
    26581 tcccctattt taaaaaaatg tgccttattg ccgataggct atctcttgaa caccgattaa
    26641 gaagaaggtt gtcacaacga ttttcttcat ttaaaatagt agaacagagg tgagacatga
    26701 tgaaaaaaaa gttgacaaaa tccaataaaa atgttgtttt gacaggtact ttagcaggga
    26761 ttggggaata tatcgggatt gatcccactg ttatccgtgt gctttatgta ttcttaagct
    26821 tagttgcttt tggaagtcca atcattttat acattttatt agctttgatt atcccatctg
    26881 cgcgttctgc acgaacaaac tatggacata acaatgcata ttatgaaaaa aacaattatc
    26941 gtgaacaaac aaaaaaacgc aaagaagcgg aaaaaatcga tgatgacgaa tggagtgact
    27001 tttaatgtcg tactttcagc gtattttggt taatacgtta acattcatat cgttggctgt
    27061 tctttttcct gcgatggtcc atgtgagcag tatttggacg gccgtccttg ccagcttcgt
    27121 attatctgtg ttgaacatgt ttgtcaaacc gattttgacg atcctgtccc tgccctttac
    27181 attagtcaca ttgggattgt ttacgtttgt tatcaatgca gcgattctta aaatgacttc
    27241 cttttttgta ggagcagaac attttagttt ttcttcattt ggtgcagcgt tattcgtagc
    27301 tatcttgatg tcacttgtca atgtaattgt tagtgaacat aacagcagaa aataaaaaaa
    27361 gctgtgccga gatctcggcg cagctttt
//
LOCUS       DAZKKZ010000038        27346 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.038, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000038 DAZKKZ010000000
VERSION     DAZKKZ010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 27346)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27346)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27346
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.038"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..709)
                     /locus_tag="ACG8LA_001731"
     CDS             complement(<1..709)
                     /locus_tag="ACG8LA_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HFQ0204030.1"
                     /translation="MTYTHLTTDELVMIESYFKINQSVAKTAHFLNRSRQTIHKVYLF
                     FKQGKSALEYYQQYKKNKSNCGRRPLVLPEEQSEYIQRKVVQGWTPDVIVGRAAFPIR
                     CSARTIYRMFKKGLFNPSDLPMKGKRKPNGHQERRGKQAFRRSIHEREKDYSQFSNEF
                     GHLEGDTIVGLKHKSAVITLVERLSKVIITLKPCGRQAIDIENKLNHWFESVPKNLFK
                     SITFDCGKEFSNWKQISN"
     gene            975..1319
                     /locus_tag="ACG8LA_001732"
     CDS             975..1319
                     /locus_tag="ACG8LA_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051920 - peroxiredoxin activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HFQ0204031.1"
                     /translation="MAEKQTAGRDQLGDFAPKFAELNDDVLFGQVWSREELSAHQRSI
                     ITISALISGGNFEQLPAHLKIGKQNGITSEEIAEIITHLAFYVGWPKAWSAFSLAKEI
                     YLEENSEDKKEA"
     gene            1320..1739
                     /locus_tag="ACG8LA_001733"
                     /pseudo
     CDS             1320..1739
                     /locus_tag="ACG8LA_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297629.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
     gene            complement(1831..2181)
                     /locus_tag="ACG8LA_001734"
     CDS             complement(1831..2181)
                     /locus_tag="ACG8LA_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204032.1"
                     /translation="MEKELSKRIIDELLTYLYSHEITEIRIGVEFAEEGLFIEIQGTA
                     ETQPEDLDVLADLLNNPRDPSMEIYYQELLGNPRHDREDYHLLGSLIDDVEIMYAQPI
                     INIKIFRRASHSYY"
     gene            complement(2147..3478)
                     /locus_tag="ACG8LA_001735"
     CDS             complement(2147..3478)
                     /locus_tag="ACG8LA_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1576 domain-containing protein"
                     /protein_id="HFQ0204033.1"
                     /translation="MENETDVIYIHPQKRIVSQKRKYFYLGFTGVFFLFIGLLSNTPT
                     DNWSGLLTILTSPSNLLTDYFALGGFGSAFINVGILTLLSVLLAYRHKVILNGPLFAS
                     ILTVTGFSFFGKNLYNSISIILGVYLYAVFVNKPFSQYIMIGLFGSALSPVVSYITFG
                     MRFPLLIGILLGNLAGIAIGLLLPPLAAQTLVFHRGFTLYNIGFTSGLIAMTFTAVLR
                     LFSYSIVENTLVFNEYHFPLIWIIFGFFSLTVGIGFYYNSFRLLGIREIFDSSGKLTT
                     DFIANSGIGATLINIGLVGLMLSSYVLLVGGQLNGPVIGAILSAVGFSAFGCHLKNSF
                     PILVGIFIASLFGTFHEITSTGMLVAAVFGTGLAPISGFYGSFYGVIAGVLHIALVHN
                     VSTLHGGLNLYNSGFSTGFVAGILVPILDNFTAVRKEKKTLGKRIIKKNHR"
     gene            3734..4300
                     /locus_tag="ACG8LA_001736"
     CDS             3734..4300
                     /locus_tag="ACG8LA_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFQ0204034.1"
                     /translation="MRRKVYTKDQILKAAYDVVAKEGFKGFTARNIAKKMGISTQPIY
                     LEFKNMEDLKNTLLDSIFEQLKEDVFPIERTGDKIIDLGLNYIYFAKKHHSLYMALYI
                     DEHGDGKKMHDFSYNYFREIVKEDERYNQLSDEYVDALHTGTWVAVTGLASLMSSNIM
                     HPTEEQIIALIKRTIDSILALDNPEIIR"
     gene            4445..4532
                     /locus_tag="ACG8LA_001737"
     tRNA            4445..4532
                     /locus_tag="ACG8LA_001737"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4477..4479,aa:Ser,seq:cga)
     gene            4866..5840
                     /gene="bsh"
                     /locus_tag="ACG8LA_001738"
     CDS             4866..5840
                     /gene="bsh"
                     /locus_tag="ACG8LA_001738"
                     /EC_number="3.5.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase"
                     /protein_id="HFQ0204035.1"
                     /translation="MCTAITYATKDHYFGRNFDYEMSYNEVVTITPRNYRFDFRKVKN
                     LDKHYAMIGIAAGVSNYPLYYEATNEKGLSMAGLNFPGNADYKELQEGKDNVAPFEFI
                     PWILGQCSTIDEAKELLATINLVNIDFSEKLPLSPLHWLLADKEKSIVIESMKDGLHL
                     YDNPVGVLTNNPPFDYQLFNLNNYRSLSNGTPENHFSNQISLNVYSRGMGGLGLPGDL
                     SSVSRFVKATFTKMNAASGDSESESISQFFHILGSVEQQKGVCDTGERKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAVNMNKEDLDRHELVSYPVIKEQQINYVN"
     gene            6165..8060
                     /gene="asnB"
                     /locus_tag="ACG8LA_001739"
     CDS             6165..8060
                     /gene="asnB"
                     /locus_tag="ACG8LA_001739"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HFQ0204036.1"
                     /translation="MCGIVGFVNDKDNKKTIINTMMDRIVHRGPNSSGEYIDKHVALG
                     FRRLSIIDLEGGTQPIYNEDRTKIIIFNGEIYNYQPLREELIAAGHVFQTHADTEVLL
                     HGYEEWGTELLQKIRGMFAFAIWDNEKNELFGARDHFGIKPYYYAEMNGTFMFGSEIK
                     SFLPHPDFNKELNKEALKPYMTFQYSPLNGETFFKDVYRLPEGHYYTYKDGKIDIQQY
                     WDADFETKETHSRQEWIEKIDETVQASIEAHTVSDVEVGSFLSSGVDSSYVTSVLKPD
                     HSFSIGFDDKTYNEAIEARKLTELLDLDNTAAVIDGDMSFKAFPLIQYHLDEPDSNPS
                     CVPLYFLANLASQSVRVVQSGEGADELFAGYQTYGFHTNSKFIRVIAQGLKKLPKGTR
                     YNLGRKIGKMKNFHGRIHLYESLAPAKEYFIGHARVFEESEASEVLTPKYQTAPSVDE
                     IMTVHYEKTEGIKDEVNKMQYVDLHQWMPKDILLKADKLSMASSLEVRVPLLDIEVMK
                     LAQQIPSKFLLNQNNTKDIFRQAANKHLPEEWSNRVKLGFPVPIKAWLKEEHGYEQVK
                     ALFEADFAKEFFDQEKIMKLLDDHHEGRKEEQRKIWTIFSFLTWYKVYFVDETIPQAE
                     AIDYVTV"
     gene            complement(8255..8701)
                     /locus_tag="ACG8LA_001740"
     CDS             complement(8255..8701)
                     /locus_tag="ACG8LA_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HFQ0204037.1"
                     /translation="MPWNMKDFPASMKNLDKLTRKKAIDIANALLDEGYPDNRAIPIA
                     IDQAKKWYEDASESEKRTFEKEKNPSKTDEHDTNPRAGKLLDSDVIVEYEEEQWIVKS
                     KGAKKASNHFDTKKEAIEKGKQVAQNKESTLFIYKKDGTKEKEIDY"
     gene            8929..9078
                     /gene="rpmG"
                     /locus_tag="ACG8LA_001741"
     CDS             8929..9078
                     /gene="rpmG"
                     /locus_tag="ACG8LA_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HFQ0204038.1"
                     /translation="MRVNITLECTSCKERNYLTSKNKRNNPDRLEKQKYCPRERKVTL
                     HRETK"
     gene            9166..9684
                     /locus_tag="ACG8LA_001742"
     CDS             9166..9684
                     /locus_tag="ACG8LA_001742"
                     /EC_number="1.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004146 - dihydrofolate reductase activity
                     [Evidence IEA];
                     GO_function: GO:0005542 - folic acid binding [Evidence
                     IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HFQ0204039.1"
                     /translation="MFISMWAQDKNGLIGKNGLLPWRLPNDMRFFREHTMDRILVMGR
                     KTYEGMGDLSLPYRHIIVLTTQPNFRTKENAEVMHSIDELLSYSQTISEDIYVSGGSR
                     IFQELLPYTGRIWRTLIDSTFEGDTYIGNIDFSDFALIEEYEGITDQENLYAHRFQKW
                     ERVKNRVASKEE"
     gene            complement(9761..10717)
                     /locus_tag="ACG8LA_001743"
     CDS             complement(9761..10717)
                     /locus_tag="ACG8LA_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFQ0204040.1"
                     /translation="MKLKTKVFTLSSILLLAGVLSACSPSSDKETATTANSTTSSNST
                     HTVTDTLGHKVEIPNAPKRIIGSYLEDYLIALGEKPIAQWTVGSGSIQDYLQDDLKDV
                     PTISYDLPYEKVLSFEPDLLLISSSATVEGGKYEQYSKIAPTYVVKNGTDVTWEEQLK
                     DVGKALAKEKEAEKIISDYQKSIKKTREELADKIENKTAAVLWVTNNSAFMVSKNRSS
                     GRIVYDDLEFGVPDLVEEVSKKATSDWSAVSSEKLAELDADYIILVNSDKDAAMFNEP
                     SWKNLKAVTDNHVLQFGPESSWLYNGPIASQEMVNDIKEKLN"
     gene            10883..11689
                     /locus_tag="ACG8LA_001744"
     CDS             10883..11689
                     /locus_tag="ACG8LA_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0204041.1"
                     /translation="MTRLRAADIAAGYENKKIIENMSVTIPEGKITSLIGPNGSGKST
                     LLKSFTRILPVKSGKIIVNNSDISTYSSKELAKKIALLAQTSEHPTGMTVEEVVSYGR
                     YPYQKLFSGMDTQDHEAIEWALDATGLAGFRMRDIATLSGGQTQRVWIAMALAQETDI
                     LILDEPTTFLDPAHQLEILQLLTEINQMKQTTILMSIHDINHASRFSDYLLAMKNGKL
                     ITEGTPEEVITKECMKKIFEIDATIVTLPRTNKPVFLTYDLLPKEQEDQL"
     gene            11686..12675
                     /locus_tag="ACG8LA_001745"
     CDS             11686..12675
                     /locus_tag="ACG8LA_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FecCD family ABC transporter permease"
                     /protein_id="HFQ0204042.1"
                     /translation="MRTMKKNRLLLLVCFVLLIIFFVALSNGAATVGKADFWQALFDF
                     DRSKQSHQIIRNIRLPRVAGAFLVGSCFALSGALMQGVTRNPLADSGLLGINAGASLA
                     MALSFAFWPKASDFSVFLMSLAGSFAVTLLVFGFLQFSKMGMNPLQLILAGVAISSFF
                     TAISQALTQFFNLQQDLAFWFVGGAANITWKQLAVLFPLYILAVLVSFSLGKAISLIH
                     LSETHALALGSHPKRTRLIVFCLVAVLAAIAVSLVGPVSFIGLLVPPVVRGMVGTDYR
                     YVLPVSFLVGGGLVMLADFTARMINPPFETPFGLVIALIGVPFLLIQVRREQR"
     gene            12672..13676
                     /locus_tag="ACG8LA_001746"
     CDS             12672..13676
                     /locus_tag="ACG8LA_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FecCD family ABC transporter permease"
                     /protein_id="HFQ0204043.1"
                     /translation="MKKIYWTFYFLLFVLVILSIGSLMIGTPFIYLDQLFATFIGKES
                     SSLALIVREFRVPRLLISLLAGACLGVSGYILQGVTRNELADSSILGINAGAGFLVML
                     YLGFFSHYSLPFLLLVVAFLGGVLAACCVYLAAYDRNGFLGMNRILLSGIAVNAGLSA
                     LTLLCTIQLSKENYGFVNAWLAGSIWGASWPYVWALLPWAVILIPLGGLYAQRIVLLS
                     FGQERAQGLGLNVAKSQKILLLLAVALASGSVAVTGSLSFVGLLAPHAAKLVVRKENN
                     WTFVLSGLFGSIFLLSADMVARVILLSGEVPTGILIALFGAPYFLYALFIRQKHALNS
                     "
     gene            13808..14350
                     /locus_tag="ACG8LA_001747"
     CDS             13808..14350
                     /locus_tag="ACG8LA_001747"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030272 - 5-formyltetrahydrofolate
                     cyclo-ligase activity [Evidence IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HFQ0204044.1"
                     /translation="MDQLKVRLRRKGIEKLKNLAKSGKKKEKEQRIYKQLFASEYWKS
                     AKVIGTTLSNEFELDTQPVIQRAEKEQKKIVVPKTLPKRQMAFYEMDEQSVLVRSSFG
                     VLEPQSEKLYLPEMIDLLIVPGIIYNRAGYRIGFGGGYYDRYLNNFHKKTCSLVFREQ
                     LNEQWQPESFDQKIQQLFID"
     gene            14370..15068
                     /locus_tag="ACG8LA_001748"
     CDS             14370..15068
                     /locus_tag="ACG8LA_001748"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HFQ0204045.1"
                     /translation="MNYQQQIKLRAWLRRPLWTYAFLGIQTAVFLMMELFPRLEIPYY
                     AGMYGPYLVHFNEWWRLVTPIFIHFGLMHFVMNSLILYFMGQQIEAIYGHWRFFLIYM
                     FSGIMGNTASFAFNEANVLSGGASTSIFGLFGALFILGFHFKHNPAIQQLVRHFLLFI
                     VLTFVFGLLDTSVDVWGHVGGLIGGLVLGNVLGLPKQQTSYSIHQRILSTLVFVFLFV
                     ICILLGLKKYGLLV"
     gene            15089..15301
                     /locus_tag="ACG8LA_001749"
     CDS             15089..15301
                     /locus_tag="ACG8LA_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HFQ0204046.1"
                     /translation="MESLYDVQQLFKKFGIFIYVGARIYDIELMTIELRNLYDSRLID
                     HDTYMTAWRILKREHRIEESRKKGNL"
     gene            15301..16263
                     /locus_tag="ACG8LA_001750"
     CDS             15301..16263
                     /locus_tag="ACG8LA_001750"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004340 - glucokinase activity [Evidence
                     IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA];
                     GO_process: GO:0051156 - glucose 6-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HFQ0204047.1"
                     /translation="MDKKIIGIDLGGTTAKFAILTPEGEIQQKWSIDTNILDDGKHIV
                     PEIIESINHRLNLYNMKAEDFIGIGMGTPGSVDSEAGTVIGAYNLNWTEVQFVKKLIE
                     AGTGIKFAIDNDANVAALGERWKGAGENDPDVVFVTLGTGVGGGIVAGGNLIHGVSGA
                     GGEIGHITVDPEGFECTCGKRGCLETVSSATGVVRLGRFLAEEYAGDSKLKAMLDNGE
                     EVTSKDIFEMAQEDDPFALMVVDRVCFYLGLACGNLGNTLNPSSIVLGGGVSAAGEFL
                     RSRVEKYFKEFTFPQVRESTKIKLAELGNEAGVIGAASLALKFA"
     gene            16281..16676
                     /locus_tag="ACG8LA_001751"
     CDS             16281..16676
                     /locus_tag="ACG8LA_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HFQ0204048.1"
                     /translation="MVLWVINIILLLIVLAIILWEVYLRVMAKRSATTLTEEEFREGM
                     RKAQVIDVREKDVFDAGHILGARNIPYTVLKDSLGSIRKDQPVYIYDQKKSLSIRTAN
                     KLRKAGYQEIYLLKGGYDGWSGKIKSKKV"
     gene            16839..17204
                     /locus_tag="ACG8LA_001752"
     CDS             16839..17204
                     /locus_tag="ACG8LA_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 domain-containing protein"
                     /protein_id="HFQ0204049.1"
                     /translation="MIKLKRVYLDAEKEDGYRILVDRFWPRGISKEKAQLDLWLKEIA
                     PSNEARKTFDHVPERFASFAKKYQQELIFEEEKKQAIFKLSQLMKEHPVITFVYGAKN
                     EHQNHAVLLKKFIEMEACK"
     gene            17201..19012
                     /locus_tag="ACG8LA_001753"
     CDS             17201..19012
                     /locus_tag="ACG8LA_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD/NAD(P)-binding protein"
                     /protein_id="HFQ0204050.1"
                     /translation="MKIGIIGAGPRGLSVAERILHNNQDRHSLELFLFDPNGPGGRVW
                     RLNQPPELLMNSVSQQVTLFTDETLSSGGLVTQGPNLFQWSKGPATDYIEQTVTKNKQ
                     LIIEEINRLEKDQQSTRCLYGLYQRWFFSKLQEEFPASIQFVYSLVKKVSKRKDGYLL
                     QTDQQSYSIDQLVLASGHWENDETEEERVWVDYAKKNVLLYQLPSNPADVDLSKIPPK
                     ENVFLRGLGLSFFDYVGLFTVSRGGRFENEKGKLVYHPSGKEPIVYSGSRRGLPYYPR
                     GRNQKQGGAMAWPRLLTKENLEQWHQSGFLTGETFFDYLKKDVELFYYKKIIEEYHLP
                     IPKKNFEHDFLSLSSEECLGKHPALIPYRWDWSYLETPLAYQNEPFSEASRIFIEGQI
                     KEAEKGNCTGAFASTFDALKDWRDPIRQAIEWHVFSAKEYKEILWGWFTHLNSFLTIG
                     PPIIRTKELAALIDAGIFHLIEPPFDIQQKHNRYVISLQDKEISSRYLIEARLPQTSF
                     SRSSNPVIKNLKENKLVRPFSFSDNTGSYHSEAIDVERGTNRVIDASGEIQSDFYCYG
                     IPVEGVDWLTAAVARPYTDPWNLRQADKIAQLILTDK"
     gene            complement(19074..19241)
                     /locus_tag="ACG8LA_001754"
     CDS             complement(19074..19241)
                     /locus_tag="ACG8LA_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HFQ0204051.1"
                     /translation="MKKFVSGILVGSLATAAAVAGLVASVKKTVIDPIDEKEAMIEEN
                     RKKAMRKRVSR"
     gene            19489..20478
                     /gene="galE"
                     /locus_tag="ACG8LA_001755"
     CDS             19489..20478
                     /gene="galE"
                     /locus_tag="ACG8LA_001755"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HFQ0204052.1"
                     /translation="MTILVLGGAGYIGSHAVDQLVQKGYQVAVVDNLLTGHKQAVHPD
                     AHFYEGDIRDKEFLRSVFEKEPIEGVIHFAASSLVGESVEKPLMYFNNNVYGMQILLE
                     VMHEFNVNKIVFSSTAATYGEPKESPITEDTPANPKNPYGESKLMMEKMMKWCDQAYG
                     MRYVALRYFNVAGAKADASIGEDHTPETHLVPIILQVALGQRKALAVYGDDYDTPDGT
                     CIRDYVQVEDLIAAHILALEYLKEGNESNFFNLGSSKGYSVKEMLEAAREVTGKEIPA
                     EIAPRRAGDPSRLVASSEKAREILGWKPEYTDIKAIIKTAWDWHVSHPNGYEE"
     gene            20490..21974
                     /gene="galT"
                     /locus_tag="ACG8LA_001756"
     CDS             20490..21974
                     /gene="galT"
                     /locus_tag="ACG8LA_001756"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0017103 - UTP:galactose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0019388 - galactose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HFQ0204053.1"
                     /translation="MSISQTICDFATLAIEAGGWMEMDRLYLQNRLLGMVGEDALESI
                     EVRPVKEESVDLLDQLVAKARENGVLSELPAEQEIFEAQLMDFLTPPPSVVNAFFAQH
                     YSKSPEEATEYFFNLSKKNDYIKTRAIAKNIKFPAESEYGELEITINLSKPEKDPKQI
                     AAEREAVKVDYPTCMLCMENEGYRGRLNYPARTNHRIIRMNLDGESWGFQYSPYAYYN
                     EHSIILSEQHRPMKITKETFARLLRITEVLPHYFVGSNADLPIVGGSILSHDHYQAGR
                     HEFPMAKAPIEKLIKLEDYPQVIAGVVKWPMSVIRLQSTEKNLLIEAANSVLEKWKAY
                     SDETVSIRAFSADGTPHHTITPIARRRDNYFELDLVLRDNNVSEEHPDGIFHPHKDVQ
                     HIKKENIGLIEVMGLAVLPPRLKPELVEVEHFLLGEENQMAEYHRPWAEQLKKEHPDL
                     TKDTVTDVVQKSVGQVFARVLEDAGVFKRDEKGQAAFERFTAIL"
     gene            21998..22978
                     /locus_tag="ACG8LA_001757"
     CDS             21998..22978
                     /locus_tag="ACG8LA_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFQ0204054.1"
                     /translation="MATIKDIAQLAGVSPATVSRVLNYDPDLSVGLATKQKIFEAAER
                     LNYTKHRKNAANTKQTLRLIQWYDDTEELEDLYYLSIRLGIEKKAEEANVTLLKETWD
                     SISDLPADGTIALGKFDEAQLLEMKGSQNALLLVDSDGTSQGIDSLVVDFKSSVQKVI
                     EHFVSHKAQHIAMLAGTEYTKKNHQRLKDPRIMAFQQVLAEKGYDEGPIIEADFSVES
                     GYQAVKQYLKTNPHVPDALFAANDALAIGALKAIQEKGLVVPEDISVMGFNDVSVAKY
                     VTPSLSTVKVYTEWMGELAVETILQLSNSKAPVSRKIIVETELIIRESTK"
     gene            23169..23891
                     /gene="tsaB"
                     /locus_tag="ACG8LA_001758"
     CDS             23169..23891
                     /gene="tsaB"
                     /locus_tag="ACG8LA_001758"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HFQ0204055.1"
                     /translation="MITLGIDTANQTLAIGVVEDEQILGQIQTNIKRNHSVTLMPAID
                     QLFADLQISPKDIDRIAVSDGPGSYTGLRIGVTTAKTIAYTLDKELVGVSSLKTIAAN
                     CIGVDKIIVPMFDARRKNVYAGAYRWKENRLEIVLEDVHISASDLFTQLQKLNEAIYF
                     VGSDCHKFFYEIKEILPSAMINTVPAWDIPSGVTVAQLGALAEPVAEKQAFLPRYLKR
                     VEAEEKWLETHTPGDESYVEKI"
     gene            23875..24417
                     /gene="rimI"
                     /locus_tag="ACG8LA_001759"
     CDS             23875..24417
                     /gene="rimI"
                     /locus_tag="ACG8LA_001759"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008999 -
                     peptide-alanine-alpha-N-acetyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HFQ0204056.1"
                     /translation="MLKKFRAYARSFFQDKMIYTEKTIEQIDRRYVLRELTTEDIKEL
                     LDVEREVYNGELPWTKSAFISELKSPLPHLYLGIFDNGRMIGFIGSRAFGLDCHITNI
                     AVRPAYQRKRIGSLLIDEIENFAIMNRCETMSLEVRMSNQDAQRLYRKLGFQATTIKK
                     RYYTETKEDALDMIKLLENE"
     gene            24424..24888
                     /gene="rimI"
                     /locus_tag="ACG8LA_001760"
     CDS             24424..24888
                     /gene="rimI"
                     /locus_tag="ACG8LA_001760"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008999 -
                     peptide-alanine-alpha-N-acetyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HFQ0204057.1"
                     /translation="MICRKKDFDEAYLAECVWMISENAYPHGSPWTKMQFLADIQQPH
                     SDYLLLVEDNQICGFIGYSKVIDEVEITNIAVAVSEQGKGHARHLLQLLITEQIKDSL
                     HVFLEVRLSNEAARKLYESEKFRILGKRKSYYRNPTEDAIIMSRKLKTETMK"
     gene            24885..25901
                     /gene="tsaD"
                     /locus_tag="ACG8LA_001761"
     CDS             24885..25901
                     /gene="tsaD"
                     /locus_tag="ACG8LA_001761"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HFQ0204058.1"
                     /translation="MNEELILAIESSCDETSVAVVRNGTEILSNIVASQINSHKRFGG
                     VVPEVASRHHVEQITLCLEDALVEAGVSAEDLSAVAVTYGPGLVGSLLIGISAAKAFA
                     WAHQLPLIPVNHMAGHIYAARLVKPFQFPLMALLVSGGHTELVYMQEDGSYEIIGETR
                     DDAAGEAYDKVGRVLGLSYPSGKEIDQLAHQGKDNYHFPRAMIHEDNYDFSFSGLKSA
                     FINLVHNAQQRGEDLDKNDLAASFQASVIDVLITKTLRACQNYPVKQLIVAGGVAANQ
                     GLREGLQDALATKLPEVELVIPPLRLCGDNAAMIGAAAHVEMQKRNFASYQLNADPSL
                     VLSE"
     gene            complement(26473..27174)
                     /locus_tag="ACG8LA_001762"
     CDS             complement(26473..27174)
                     /locus_tag="ACG8LA_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HFQ0204059.1"
                     /translation="MRVNKIDFHFSKLRYQPDFEHFSDEEFQQIKEHTVLRSYKKGQI
                     LFDDGDPRQRLYILTKGLVRLERYDESATYYYYDYVNTNNLFPMSGMFGEETYTYTAQ
                     AMTDIETFYLPVSYYEKLARKNPEQLIYMIQKISKVVEIHELRIQIGLTSSAFDRVKQ
                     NLFILKEELGVPTKDGHITIPYPITLKELAVNSGTTRETAGQVIKQLRDSGLLDYDKK
                     RFTFCKTATTPAMRE"
BASE COUNT         8821 a         4693 c         5674 g         8158 t
ORIGIN      
        1 cattactgat ctgtttccaa tttgaaaatt cctttccaca atcaaaagtg atggatttga
       61 atagattttt cggtacagat tcaaaccaat gatttaattt gttttcaata tcaatcgctt
      121 gtctaccaca cggtttcaat gtgatgataa cttttgataa tcgctcaact aaggtaatta
      181 cagcactttt atgtttcaaa cctacgatag tgtcaccttc aaggtgacca aactcatttg
      241 agaattggct ataatctttt tcacgttcat gaatagagcg acggaaagct tgttttccac
      301 gtctttcttg atgtccattt ggtttacgct tgcctttcat cggtaagtca gaaggattaa
      361 atagcccctt tttgaacata cgataaatgg tacgagcaga acaacgaata ggaaacgctg
      421 cacgaccaac aatcacatcg ggtgtccatc cttgaacaac ctttctttga atatattctg
      481 attgttcctc aggtaaaaca agcgggcgtc taccacagtt tgatttgttt ttcttatact
      541 gttgatagta ctctaaggct gattttcctt gcttgaagaa caggtatact ttatggatcg
      601 tttgtcttga acgattcaag aaatgcgcag ttttcgcaac agattgattt attttgaaat
      661 aagactctat cattacaagt tcatccgttg taagatgggt ataggtcatt tgtactcact
      721 ccttataatt ctttggacgg aactattttg agtgtagcac aaatgacttt tttagttgtc
      781 tagcttaatt ttacaatcgg cgaataaaaa aagcgttagc aactatgctt aaaaagcata
      841 tcgactgaat aaactaagca ttggacaggc tgaaagacta catttaaaat gaaatgcgaa
      901 gaaacaatag aaaataaagt tgccttagaa ccatagttga atcacctaac agtcgtgaag
      961 ggagaataag agaaatggca gaaaaacaaa ccgcaggacg agatcaatta ggagattttg
     1021 caccaaaatt tgcagaattg aatgatgatg ttttatttgg acaagtatgg tccagagaag
     1081 aattatctgc tcatcagcgt agtatcatca ccatatctgc attaatttca ggaggaaatt
     1141 ttgaacaatt gccagctcat ctgaagattg gcaagcaaaa tggcattact agtgaagaaa
     1201 tagcagaaat cattacccat ttagcttttt atgtaggatg gccaaaagct tggtcagctt
     1261 ttagtttagc aaaagaaatc tatttagaag aaaatagcga agataagaaa gaggcgtaaa
     1321 tgacgacaaa acacgaagaa atacacaatg gcgtgatttt tccagcaggt gaaaaaaacg
     1381 aagcttacgc tcaagtattt accgggtaaa gctatctgaa tatgttagtg aatgatcccg
     1441 aagtttctgt tggtgtaggt aatgtaactt ttgaaccagg ttgtcgcaat cactggcatg
     1501 tccataaaga cggctatcaa atcttacttg tgaccggagg agaaggctgg tatcaggaag
     1561 aaggaaagcc agcaagacga ttaatggctg gagatgtcgt cgtaacgcac aaagggatta
     1621 aacattggca tggtgcgaca aaagacagtt ggtttgaaca tttggcgatc actgctggta
     1681 attcagagtt tttagaacct gtaacagatg aagtgtatga aggattggaa aatcaataat
     1741 gtcaagcttg aacagctcct gaaagtagat tttaatcgaa ctttcaggag ctgctttttt
     1801 gattcagtct tttataaata gaaaataggg ttaataatag gaatgagaag cacgtcgaaa
     1861 gatcttaata ttgataatcg gctgggcata catgatttcc acgtcatcaa tcaaactacc
     1921 taacagatga taatcttccc gatcatgtcg gggattacct aatagttctt gataatagat
     1981 ttccatacta gggtcccgag gattgttcag caaatcagca agtacatcta aatcttctgg
     2041 ctgagtttct gccgtaccct gtatctctat gaaaagccct tcctcagcaa attctactcc
     2101 aatacgtatt tcagttattt catgggaata taaataagta agaagctcat cgatgattct
     2161 ttttgataat tctttttcca agtgtctttt tttcctttct gacagcggta aagttatcta
     2221 gtatcggtac aaggatacct gcaacgaaac cagttgaaaa accactgtta tatagattta
     2281 gtcctccgtg caaagtgctg acgttatgga caagagcaat atgtagtaca ccagctatta
     2341 caccgtaaaa actgccgtaa aaaccgctta tgggcgcgag acctgtccca aacacagctg
     2401 caacaagcat gccagtactg gtgatctcat gaaaagttcc aaacaaagaa gcaataaata
     2461 ttccgactag tatcggaaaa ctgtttttta aatgacaacc aaaagcactg aaacccaccg
     2521 cagataaaat agcaccgatg acaggtccat ttaactgacc gccaaccagc aaaacataag
     2581 aagacagcat cagaccaact aagcctatgt tgatcaaagt agcaccaata ccagaattag
     2641 caatgaaatc agttgtcaat tttccagatg aatcgaaaat ttctcgaatc cccaaaagcc
     2701 gaaaggaatt ataatagaaa ccaattccga ctgtcagcga aaaaaagcca aaaataatcc
     2761 aaatgagagg aaagtgatat tcattgaaaa ccaatgtatt ttcgacgatt gaatagctga
     2821 ataacctcaa aacagcagta aaagtcatcg caatcaaccc agaggtgaat ccaatattat
     2881 aaagtgtgaa tccacgatgg aaaactaaag tttgagcagc taagggcgga agaagtagac
     2941 caattgctat gccagctaaa ttccccaata aaatacctat cagtaaagga aaacgcatac
     3001 caaaagtgat ataactaacg accggtgata atgcgctacc aaacagtccg atcatgatgt
     3061 actgagaaaa aggtttattg acaaatacag cgtatagata cacacctaaa atgattgaga
     3121 tagaattata aaggtttttg ccaaaaaaag agaaaccggt aactgttaga atcgaagcaa
     3181 ataagggacc gtttaaaatc accttgtgcc gataagctaa aagcacagaa agtaaggtca
     3241 aaatccctac atttatgaat gcgcttccga aaccgcctaa agcaaaataa tctgtcaaaa
     3301 gattgcttgg cgaggtaaga atagttagca atccactcca attatcagta ggagtattag
     3361 aaagcaagcc aataaaaaga aaaaaaacac ctgtaaaacc aagataaaaa tactttcttt
     3421 tctgtgaaac gattcgtttt tgaggatgaa tataaataac gtcagtttcg ttttccatta
     3481 cacaccttct ttttcatttt ctttaactat aacttgaaat gaaagatttg gacaactatt
     3541 atttaggtca aaactaaaaa tgtaagggaa cccattgaat ttaaccaaat ttttttaatt
     3601 ttgcaaaaaa aagttaaaga agactgaaaa aaaatttaaa atataacgtt ttgagtaaaa
     3661 tgtttgcaaa aaatgctaaa aatagggtac aataaaacaa catatactgc agtaaagaag
     3721 tgggggagtt ttaatgagaa gaaaagtcta taccaaggat caaattctaa aagctgctta
     3781 tgatgttgtt gcaaaggaag ggtttaaagg atttactgcg agaaatattg ctaaaaagat
     3841 ggggatttcg acacagccga tttatctgga attcaaaaac atggaagatt taaaaaatac
     3901 gttgctggat tctatctttg aacaactaaa agaagatgtt ttccctattg aacgtactgg
     3961 tgataaaatc attgatctcg gtttgaacta tatctacttt gcaaaaaagc atcatagtct
     4021 ttacatggca ttgtacattg atgaacatgg ggacggaaag aaaatgcatg atttttcata
     4081 caattatttc cgtgaaatag ttaaagaaga tgaaagatac aatcaattat cggatgaata
     4141 tgtcgatgct ctgcatactg gtacatgggt agcagtgact ggcttagcgt cattgatgtc
     4201 atcaaacatc atgcatccaa cagaagaaca aatcattgca ctgatcaaac ggacaattga
     4261 ctcgatttta gcattagata atcctgaaat aatcagatag tgttctatca gtatgaattt
     4321 gatcggtaag tccgttggct gcaaactgtc aatggacttt tttgctaaaa aaagcgattt
     4381 ctgttattta tctattagaa ataggcttga catttcgtga aaaaagttta aaaatagtac
     4441 ttacggaagg ttggcagagt ggtaatgcac cggactcgaa atccggcgaa ccggctaata
     4501 ccggcgcgca ggttcaaatc ctgtaccttc cttatatcaa cgattagagg ttgtgaagaa
     4561 gctgtcctgc atcaagtaat aagaacggcc aaacaaaaat agcttttcct attttttcgt
     4621 ttgattgggc ttattaccgc agatgcaagc ttttgaacac cgtttgttcg gaataagggg
     4681 ctgtgacaag acttttgtca cagcccctta ttgttgtact tttaacctac aatatttttt
     4741 gattccccct gagtactatt ttttataaat gctagtaaat caatcttctt tggccttttt
     4801 ttgataaaaa aaatactaga tgtaagataa aagtgtaaaa acgatttgtt ttaggacggg
     4861 aaacgatgtg taccgcaatc acttatgcaa cgaaagacca ttattttgga aggaattttg
     4921 attatgagat gtcttataat gaagtggtca ctattactcc aagaaattat cgtttcgatt
     4981 ttagaaaggt aaaaaattta gataaacatt atgcaatgat aggaatagca gctggggtat
     5041 ccaactatcc actctattat gaggctacaa atgaaaaagg gttgagtatg gcaggactga
     5101 attttcctgg caatgctgat tataaagaat tacaagaagg aaaagataac gttgcaccat
     5161 ttgagtttat tccatggata ctagggcaat gctcaaccat agacgaagct aaagaattat
     5221 tggctactat caatctagtc aatatcgatt ttagtgaaaa actacccttg tcacctttac
     5281 actggttatt agctgataaa gaaaaatcga tagtaattga aagtatgaaa gatggacttc
     5341 atttatatga taatcctgtc ggtgtgttga caaataatcc gccatttgat tatcaattat
     5401 ttaatctgaa caattatcgc tcgctatcaa atggaacacc agaaaatcat ttttcaaacc
     5461 agatcagctt gaatgtttat agtcgtggga tgggaggatt gggcttacct ggagatctct
     5521 cttctgtttc tcgatttgta aaagccacat ttactaaaat gaatgctgca tcaggtgatt
     5581 cagaatctga aagtatcagt caattttttc atatactagg ctcagtcgag caacaaaaag
     5641 gagtatgcga tactggagaa agaaaatacg aatatacgat ttattcttct tgctgtaacg
     5701 ttgataaagg gatttattat tatcgtacgt atgaagacag tcaaattact gctgtaaata
     5761 tgaataaaga agacttggat cgtcatgaat tggtcagtta tccagtcata aaagagcaac
     5821 agataaacta tgtcaattaa ttaatgaata gatccgtttg gtatcatatt ttctgataca
     5881 gtcataatta gacacgatct ttaggtcgtg tctttttttg ctggtttttt tggaaatagc
     5941 atccactaat atttttttaa cacgaagaga ataaggtagc ctcaaaaaag aaaacatggt
     6001 aaattagata ttgggacttt attttctgta aaaacagaaa ctttcatctt ttgttttcac
     6061 gtgacgaaat tgtaagagag aaaatattcg tccgctattt attctatgat aagatgcata
     6121 tgaatgaaat aaacagtaat tttatattag gatgtgaaag ttaaatgtgc ggtattgtag
     6181 gttttgttaa cgacaaggac aacaaaaaaa caattattaa tacaatgatg gatcgaatcg
     6241 ttcaccgtgg acctaatagt tcaggagaat atatcgataa acatgttgct ttaggattca
     6301 gaagattaag tattattgac ttagagggcg gtactcagcc tatttacaat gaagatcgga
     6361 caaagatcat tatttttaat ggcgaaatct ataattacca gcctttgaga gaagaattga
     6421 ttgcagctgg ccacgttttt caaacacatg cagatacaga agtccttttg catggttacg
     6481 aagaatgggg aacagaatta ttgcaaaaga tccgcggaat gtttgctttt gctatttggg
     6541 ataatgaaaa gaatgagtta ttcggtgcaa gagaccactt tgggatcaaa ccatattatt
     6601 atgcagaaat gaacggaaca tttatgtttg gttcagaaat caaaagtttt ctgcctcatc
     6661 ctgattttaa caaagaattg aacaaagaag cgttgaaacc ttatatgact ttccaatatt
     6721 ctccattaaa cggcgaaaca ttcttcaaag atgtctatcg tttgcctgaa ggccattatt
     6781 atacgtataa agatggaaaa atagacattc agcaatattg ggatgcagat tttgaaacaa
     6841 aagaaacgca ttcccgacaa gaatggatcg aaaaaatcga cgaaaccgtt caagcttcta
     6901 ttgaagcaca tacggtcagt gatgtagaag ttggttcttt cttatccagc ggggttgatt
     6961 ccagttatgt aacctctgta ttgaaaccag atcattcttt ctcaatcggg tttgatgata
     7021 aaacctataa tgaagcgatt gaagccagaa aactaaccga actattggac ttagataata
     7081 cagcagcagt gatcgacgga gacatgtcgt tcaaagcatt ccctttgatc cagtatcact
     7141 tagatgaacc tgattcaaat ccttcttgcg tacctttgta ctttttagca aatcttgctt
     7201 cacaaagtgt gcgggtagtc caatctggag aaggggcgga tgaactgttt gcgggatacc
     7261 aaacgtatgg attccatacg aattcaaaat tcatccgtgt gattgctcaa ggattgaaaa
     7321 aattaccaaa aggaacacgc tataatttag gacgtaaaat cggaaaaatg aaaaatttcc
     7381 atggacggat ccatttatat gaatcacttg ctcctgcaaa agaatatttt atcggtcatg
     7441 ctcgagtgtt cgaagaatca gaagcatcag aagtgttaac accaaaatat caaacagcac
     7501 catctgtgga tgaaatcatg actgttcatt acgagaaaac agaaggaatc aaagatgaag
     7561 tcaataagat gcaatatgtc gatcttcatc aatggatgcc aaaagatatc ttgttaaagg
     7621 cagataaact ttctatggca agttctttgg aagtccgagt acctttattg gatatcgaag
     7681 tcatgaaatt ggctcaacaa ataccaagta agtttttatt gaatcaaaac aacacaaaag
     7741 atattttcag acaagctgcg aacaaacatc ttccggaaga atggtcgaat cgtgtgaaat
     7801 taggattccc tgtgccaatc aaagcttggt tgaaagaaga acacggctac gaacaagtca
     7861 aagcattatt cgaagcagat tttgcaaaag aattttttga tcaagaaaaa atcatgaagt
     7921 tgctagatga ccatcacgaa ggacgtaaag aagagcaaag aaaaatctgg acaatcttca
     7981 gtttcttgac atggtataaa gtctactttg tagatgaaac gattccgcaa gcagaagcaa
     8041 tcgactatgt gactgtttga tgaaaatcaa atatcaataa aaaagaggtt ttctcctacc
     8101 gtttaacact gagtgataag aaacaatttc aaaaaacagc tcttcccgtt ttatagatat
     8161 tatgacttat ggttcggagt tggcagagga acaccattgt ttcgaacata agggggttgt
     8221 gacacgattt tcgtcacaac ccctttacat atgttcaata atcgatttct ttttcttttg
     8281 tcccatcttt tttataaatg aacaaagttg attctttgtt ttgtgctact tgctttcctt
     8341 tttcgattgc ttcttttttt gtatcaaaat ggttgcttgc cttttttgcc cctttagatt
     8401 tcacgatcca ttgttcttcc tcatattcta cgatcacatc tgaatcaagc agttttccag
     8461 cacgaggatt cgtatcgtgt tcatccgtct tgcttggatt tttttctttt tcgaaagttc
     8521 gtttttctga ttcactagca tcttcatacc atttttttgc ttgatcaatg gcaattggga
     8581 tcgcacggtt atcagggtac ccttcatcta ataatgcatt tgcgatgtcg attgcttttt
     8641 ttcttgtcaa tttatctaag tttttcattg atgcaggaaa gtccttcatg ttccatggca
     8701 tattagtatc cccctttatt aaaaaacata atctatataa acaagtgtaa gggtatttat
     8761 acaaaaagaa aaagattttg tttgagaagt aaaaccgttg tatttatcgt caagtagttt
     8821 tacttaacaa aatcgtgaaa aacactagca atctagaaaa aatcatggta agataatcaa
     8881 gtctgagagt catcttagag gattcttgta aaaatgggag ggaaaaacat gcgcgtaaac
     8941 atcactttag agtgtacttc ttgtaaagaa cgtaactatc taacaagcaa aaacaaacgt
     9001 aacaatcctg atcgtttgga aaaacaaaaa tattgcccac gcgaacgcaa agttactttg
     9061 caccgtgaaa caaaataatg tttttaaagt tctcaattcc ttgctggtca aagaattgag
     9121 acttttttta tctcaaaaca tctaaaatca taaggagcgg ataatatgtt tatttccatg
     9181 tgggcacaag ataaaaatgg tctgatcggc aaaaatggtt tgttaccatg gcgattgcca
     9241 aatgatatgc gtttctttcg cgaacacaca atggatcgaa ttttagtgat gggaagaaag
     9301 acctatgaag gaatggggga tctttcactt ccttatcgcc atatcatcgt gttgacaacg
     9361 caaccaaatt ttcgcacgaa agaaaatgcg gaagtaatgc attcgatcga tgaacttttg
     9421 tcgtatagtc aaacgatctc agaagatatc tatgtttcgg gtggtagtcg gatttttcaa
     9481 gaacttcttc cttacactgg tcggatctgg cgaacattga tcgatagcac gtttgaaggc
     9541 gatacgtata ttgggaatat tgatttttca gacttcgccc ttatagagga gtatgagggg
     9601 ataacggatc aagaaaatct atatgcccat cgttttcaaa aatgggaaag agtaaaaaat
     9661 agggttgctt caaaagaaga ataaaatcta tgcgtctagt ttgttaataa gaaaaaaagc
     9721 atctcacgac taatcgtgaa gatgcttttt ttagttaaaa tcaatttagt ttttctttga
     9781 tatcattgac catttcctga ctggcaatag gtccgttata tagccaacta gattcaggtc
     9841 cgaattgcag tacatgattg tctgtcactg cttttagatt cttccagctt ggttcattga
     9901 acatggcagc atctttgtca ctgttcacaa ggatgatgta gtcagcatct aattcagcta
     9961 gcttttcaga ggaaacagca gaccagtcag aagtggcttt tttggagacc tcttccacta
    10021 gatcaggaac accaaattcc agatcgtcgt atacgattct tccacttgac cgatttttgc
    10081 tgaccataaa ggctgagttg ttggtcaccc acaacactgc agctgtcttg ttctcgattt
    10141 tatctgctag ttcttctcga gttttcttga tggatttttg ataatcggaa atgatttttt
    10201 ctgcctcttt ttcttttgcc aaagctttgc cgacatcttt tagttgttct tcccatgtga
    10261 catctgttcc gttttttaca acataagttg gcgcgatttt gctatattgt tcgtatttcc
    10321 cgccttcgac agtagcggaa gaagaaatca acagcaaatc aggctcaaag cttaacactt
    10381 tctcataagg aaggtcataa gaaatcgttg ggacatcctt taaatcatct tgcagataat
    10441 cttgaatgga accactgcca acagtccact gggcgatagg tttttcccct agtgcaatca
    10501 gatagtcttc taagtaactg ccgatgatcc gtttgggcgc gtttggaatc tctactttat
    10561 gtccaagtgt atctgtgact gtatgagtac tattggatga agtcgtcgaa ttggcagttg
    10621 tagctgtttc tttatctgaa gagggggagc aagcgctcag tactccagcc agcagcaata
    10681 tgctagataa tgtgaatact tttgttttta atttcatttc tttcctccta acataattga
    10741 gaatctttct cattggttat tattcctgat atttcgaacg ctgtcaaccg cttcatttgg
    10801 ctatagatat gaaagtagcg cttgacgaaa tgttgaaaca gcgtcataat tgagaatgat
    10861 tttcagcgaa aggatgggtg aaatgacgag attaagagca gctgacattg cagccggcta
    10921 cgaaaacaaa aaaatcattg aaaacatgtc tgttacgatt cctgaaggga aaatcactag
    10981 tttgattggg ccaaatggaa gtggaaaatc tactttattg aaaagtttta cccgtatact
    11041 acctgtgaaa tcaggaaaga tcattgtcaa taactctgat atctctacat acagttcaaa
    11101 agaacttgca aaaaaaattg cattattagc acaaactagt gaacacccta caggtatgac
    11161 agtagaagaa gtagtatctt acggacgata cccttatcaa aaactgttca gtggcatgga
    11221 cacgcaagat catgaagcaa ttgagtgggc gttggatgct acaggtctag ctggatttcg
    11281 tatgcgggat atcgcaacgc tgtctggtgg acaaacccag cgtgtctgga tcgctatggc
    11341 gcttgctcag gaaacagata tcttgatctt ggatgaaccg acaacatttt tagatccggc
    11401 acaccaatta gagatcctac agttattgac tgaaatcaat caaatgaaac aaacaacgat
    11461 cttgatgtcg attcatgaca ttaatcatgc ttcacgtttt tcagattatt tattagcaat
    11521 gaaaaacggt aagttgatca cagaaggtac acctgaagaa gtgatcacaa aagagtgtat
    11581 gaaaaaaata tttgagattg atgcaacgat tgtcacgctt ccaagaacaa ataaaccagt
    11641 ttttctaacc tatgatttgt tgccaaaaga gcaggaggat caattatgag gactatgaag
    11701 aaaaatagac tcctgctttt ggtctgtttt gttcttttga ttattttttt tgttgctctt
    11761 tcaaatggcg cagcgactgt gggaaaagca gatttttggc aggcgttgtt tgattttgat
    11821 agatcaaaac aaagtcacca aatcatacga aatattcgtt tgcctcgtgt ggcgggagca
    11881 tttcttgtag ggagttgttt tgcattgagc ggtgcattga tgcaaggagt gacaagaaat
    11941 cctttagcag attcaggctt actaggaatc aacgcgggtg cttcgttggc aatggccctt
    12001 agttttgctt tttggcctaa agcttctgat ttttctgtgt ttctaatgtc attggcaggt
    12061 tcttttgctg taactttgct cgtatttggt tttttgcagt tttcgaaaat gggcatgaat
    12121 cctttacagc tgattttagc tggcgtagct attagttctt tttttactgc tatcagccaa
    12181 gcacttaccc aattctttaa tctgcagcag gatcttgctt tttggtttgt aggcggagct
    12241 gccaatatca catggaaaca attagcagta ttgtttcctt tatatatact tgctgttttg
    12301 gtttcttttt cattaggaaa agcaatatct ttgattcatt tgagtgaaac acatgcatta
    12361 gctcttggaa gtcatcctaa acgaacgcgg ttgattgttt tctgtctagt tgcagtgtta
    12421 gcagccattg ccgtttcgtt agtcggacct gtttcattta ttgggctgtt ggttccgcca
    12481 gttgttcgcg gaatggttgg aacggactat cgttatgttc tacctgtctc ttttttagtt
    12541 ggcggtggat tggttatgtt ggcggatttt acagcgagga tgatcaatcc cccttttgaa
    12601 acaccttttg gattagtcat tgcattgatt ggcgttccgt ttttactgat acaagtaagg
    12661 agggaacaac ggtgaaaaaa atatattgga cgttctattt cttgcttttt gtacttgtca
    12721 tcctgtctat aggtagttta atgattggta cgccttttat ttacctggat cagctttttg
    12781 ccacgttcat agggaaagaa tcatcttctt tggcgctgat tgttagagaa tttcgagttc
    12841 ctcgattact gatcagttta ttagcaggag cttgtcttgg cgtttctggt tatatcttgc
    12901 aaggagtaac aagaaatgaa ttggcagatt ctagtatatt gggcattaat gccggagcag
    12961 gatttttagt gatgctttat ttaggtttct tttcgcacta ttcgctgccg tttctattgc
    13021 tagttgtagc ctttctaggt ggtgttttag ctgcttgctg tgtctatctt gcggcctatg
    13081 atcgaaatgg ctttttgggt atgaatcgaa tcttattgtc cggtattgcc gttaatgccg
    13141 gcctttctgc attaacattg ctatgcacga tccaattatc taaggaaaat tatggatttg
    13201 tgaatgcatg gttagcggga tcaatctggg gtgcgagctg gccttatgtt tgggcattgc
    13261 ttccatgggc ggttatctta attccgctag gaggacttta tgcacagagg attgtattgc
    13321 tatcatttgg tcaagaacgc gcgcaaggat taggccttaa cgtggctaaa agtcaaaaaa
    13381 tccttttgtt gttagctgtt gctttggcaa gcggtagtgt agcggtgaca ggtagtttat
    13441 cttttgtagg actactagct cctcatgctg cgaagctagt cgtacgtaaa gaaaataact
    13501 ggacctttgt tctgagcggt ttgttcggtt ccatttttct gcttagtgca gatatggttg
    13561 ctagagtgat tctactaagt ggggaagtac ctacaggaat tttgattgcc ctttttggtg
    13621 cgccatattt tctgtatgca ctttttatca gacaaaaaca cgcgctgaac agttgaaatt
    13681 cattaaaaaa ggaaggccaa tcatttctag gtcttctttt tattctattt atgcatttat
    13741 ttgaaagttc gattgctatt tttctttttt tcctatacca ttttatgaga gaaggaaggg
    13801 tgagtttttg gaccaattga aagtaagatt acgccggaaa ggaatcgaaa agctgaaaaa
    13861 tctggccaaa agtggcaaga aaaaggaaaa agaacagcga atctataaac agctattcgc
    13921 cagcgagtac tggaagtcag caaaagtgat agggacgact ttatcgaatg aatttgaact
    13981 ggatacacag ccggttatcc aacgagcaga aaaagaacaa aagaaaatag ttgtacctaa
    14041 aactttgccg aaacgtcaga tggcgtttta tgaaatggat gaacagtccg ttcttgtacg
    14101 ttcgagtttt ggtgttcttg agccacaatc agagaagctc tatttgccgg agatgatcga
    14161 tctcctcatt gtaccaggta ttatctacaa tagagccggt tatcgaatcg gttttggcgg
    14221 tggttattac gaccggtatt taaataattt tcataaaaaa acatgtagcc ttgtttttcg
    14281 tgaacaattg aatgaacaat ggcaaccgga gagctttgat cagaagatcc aacaattgtt
    14341 tattgactaa aatgaaatgg gaggttttca tgaattatca acagcaaata aaattgcgtg
    14401 catggttaag acgaccgtta tggacctatg cttttttagg gatacagaca gcggtcttcc
    14461 tcatgatgga attatttccg cgacttgaga tcccttatta tgccggaatg tatggtcctt
    14521 atcttgttca cttcaatgaa tggtggcgtt tagtgacacc aatcttcatc cattttggac
    14581 tgatgcattt cgtaatgaac tcactgatac tgtattttat ggggcagcaa atcgaggcaa
    14641 tctatggcca ttggcgtttt ttcttgattt atatgttcag cgggataatg ggaaatacag
    14701 caagctttgc ttttaacgaa gcgaatgttc tgtctggtgg tgcaagtact tcgatattcg
    14761 gtttgttcgg tgcgttgttt atcttagggt ttcattttaa acataaccca gcgatccagc
    14821 agctagtcag acattttctt ttatttattg tgttgacatt tgtttttggt cttctggata
    14881 cctctgtaga tgtttgggga catgtcggtg ggctaattgg cggattagtg ttagggaatg
    14941 ttttgggtct accgaaacaa cagacaagct attcgataca ccaaaggatt ctttctacac
    15001 tagtttttgt atttcttttt gtaatatgta ttttactggg tttaaaaaaa tatggtttac
    15061 ttgtataata tgaaggaagt gcttaaagat ggagagctta tatgatgtac agcagctgtt
    15121 caaaaaattt ggcatcttta tctatgtggg tgcacgcatc tatgacattg aattaatgac
    15181 tatcgaattg cgtaatctgt atgatagccg tttgattgat catgatacat acatgacagc
    15241 gtggcgcata ttaaaaagag agcaccgaat tgaagaaagc cgaaagaaag gaaatttgta
    15301 atggacaaga agattattgg gattgattta ggtggaacaa cagcaaaatt tgcaatttta
    15361 acaccagaag gagagattca gcaaaaatgg agcatcgata ccaatatttt ggatgatggt
    15421 aagcatatcg ttcctgaaat cattgaatca atcaatcatc gtttgaattt atataatatg
    15481 aaagccgaag actttatcgg aatcggcatg ggtaccccag gaagcgtgga cagcgaagct
    15541 ggaacggtta ttggtgcgta taacttaaac tggacagaag ttcaatttgt gaaaaaactg
    15601 atcgaggcag gaacaggaat caaattcgct atcgataatg acgcgaatgt tgctgcttta
    15661 ggtgaacgat ggaaaggtgc tggagaaaac gatccagacg ttgtattcgt tactctagga
    15721 acaggtgttg gcggaggtat cgttgctggc ggaaatttga ttcacggcgt gagcggagct
    15781 ggaggagaaa tcggacatat cactgtggat cctgaagggt tcgaatgtac ttgcggtaaa
    15841 cgcggatgtt tagaaactgt atctagcgct acaggtgtgg tacgcctagg tcgtttcttg
    15901 gcagaagaat acgcagggga ttcaaaactg aaagcaatgc tagacaacgg agaagaagta
    15961 acaagtaaag atatctttga aatggctcaa gaagacgatc cgtttgcatt gatggttgtt
    16021 gatcgcgtat gcttctactt aggtttagct tgcggaaact tggggaatac attaaatccg
    16081 tcaagtatcg tgttaggtgg aggagtatcg gcagcaggag aatttttacg tagccgtgta
    16141 gagaaatatt ttaaagaatt tactttcccg caagtaagag aatcaacaaa aatcaaatta
    16201 gcagagcttg gtaatgaagc tggtgtcatt ggtgctgcct cattagcctt gaaatttgct
    16261 taaaaaaacg gaggcattac atggttttat gggtaattaa tatcattttg ctattgattg
    16321 tgcttgcaat catcctttgg gaagtctatc tacgagtaat ggccaaacgt tcagcaacga
    16381 ctttgacaga agaagaattt cgagaaggaa tgagaaaagc acaagtaatc gatgttcgcg
    16441 aaaaagatgt gtttgatgct gggcatattt taggtgcaag aaacatccct tacactgttt
    16501 tgaaagattc attaggatct attcgaaaag accagcctgt ctatatttac gatcaaaaga
    16561 aaagtttgag catccgtaca gcaaataaat tacgtaaagc aggttatcaa gagatttatt
    16621 tacttaaggg tggatatgac ggatggtctg gaaaaatcaa aagtaaaaaa gtataaaaca
    16681 gatgattgta tgacagcttt aaaaaccgaa tcaatcatta gattttgacc aagatcacat
    16741 gaacggcgca atggatagtt gtgccgttca ttttttttat tttgtgctat tatctacata
    16801 tataagctaa gcgaaaaggt agaaagaagg aaacaactat gatcaaatta aaacgtgttt
    16861 accttgatgc tgaaaaagag gatggctata gaatactcgt ggatagattc tggccacgag
    16921 gaatttcaaa agaaaaagcg cagttagatc tgtggttgaa agaaattgca cctagtaatg
    16981 aagcacgcaa aacttttgac catgtaccag aacgatttgc ttcatttgca aagaaatacc
    17041 agcaagaatt gattttcgaa gaagaaaaga agcaagctat ttttaaactc agtcaactta
    17101 tgaaagaaca tccagtcatt acttttgttt atggtgcaaa aaatgaacat cagaaccatg
    17161 ctgttttatt gaaaaaattt atcgaaatgg aggcatgcaa atgaaaatag ggatcattgg
    17221 tgccggacct agaggattaa gtgtagcaga aaggattctc cataataatc aggacagaca
    17281 ttctcttgaa ctttttcttt tcgatcccaa tggtcctgga ggtcgagttt ggcggttgaa
    17341 tcagccaccg gagttattaa tgaattctgt ttctcaacaa gtgacgcttt ttacagatga
    17401 aacattgtcc agtggaggat tggtaacaca gggacccaac ttgtttcaat ggagtaaagg
    17461 acctgctaca gattatatcg aacagacggt aaccaaaaat aagcaactaa ttatagaaga
    17521 aatcaatcgt ctggaaaaag atcagcaatc tactcgatgt ttatacggac tctatcaacg
    17581 ctggtttttc tcaaagttgc aagaagaatt tccagcttct attcagtttg tttattcttt
    17641 agtaaaaaaa gtaagcaaaa gaaaagatgg ttatctttta cagacagatc agcaaagcta
    17701 ttctatcgat cagcttgttt tagcaagcgg tcactgggaa aatgatgaga cagaagaaga
    17761 aagagtgtgg gtagactacg caaagaaaaa tgttttactg tatcagcttc cttctaatcc
    17821 tgcagatgta gatctttcga agataccgcc taaagaaaat gtctttttaa gaggtctagg
    17881 cttaagtttt tttgattatg tcggattgtt tacagtatca agaggagggc gcttcgagaa
    17941 cgaaaaggga aaactggtct atcatccatc aggcaaggaa ccgattgtat acagtggatc
    18001 aagaaggggg ctcccttatt accctcgagg aagaaatcaa aagcaaggcg gagcaatggc
    18061 atggccacgg ttactaacaa aagaaaacct ggagcaatgg catcagtcgg gatttttgac
    18121 tggcgaaaca ttttttgact atctgaaaaa agacgttgag ttgttttatt acaagaaaat
    18181 catcgaagaa tatcacttgc cgattccaaa gaaaaatttt gagcatgatt ttctctccct
    18241 ctcttcagag gagtgtctcg gaaagcatcc agcactaatc ccttatagat gggattggtc
    18301 gtatttagaa actcctcttg cctatcagaa tgagcccttt tcagaagcta gccgaatatt
    18361 tattgaaggg cagataaaag aagcggaaaa aggcaattgc acaggagcat ttgcttcaac
    18421 atttgatgca ttaaaagact ggcgtgatcc aatccggcag gctattgaat ggcacgtttt
    18481 ttctgctaag gaatacaaag aaatactatg gggatggttt actcatctaa atagcttttt
    18541 aacgatcggt ccgccaatca ttcggacgaa agaattagca gcactgatag atgcgggtat
    18601 ttttcatttg atcgaaccgc catttgatat tcagcaaaag cacaaccgct atgttatttc
    18661 tctacaagat aaagaaatca gcagtcgcta tttgattgaa gctcgattgc cacaaacaag
    18721 cttttctcgt tcaagtaatc ctgtcataaa aaatttgaag gaaaacaaac ttgttcgccc
    18781 tttttcattt tcagataata caggaagtta tcattcagaa gctatagatg ttgagcgagg
    18841 tacgaatcgc gtgattgatg cttcagggga aatccagtct gacttttatt gctatggaat
    18901 acctgttgaa ggtgtggatt ggctaactgc agcagtagct agaccttata cagatccatg
    18961 gaatctgaga caggcagata aaatagcaca acttatattg actgacaaat aaaaatacgc
    19021 atgatgactt atctgttttt tagaaagtct tcatgcgtat ttttaaataa ttattaacga
    19081 gaaacgcgtt tacgcattgc ttttttacgg ttttcttcga tcattgcttc tttttcgtca
    19141 attggatcga tcactgtttt tttcacagaa gcaaccaaac cagcaacggc agcggctgtt
    19201 gccagacttc ctactaatat tccagataca aattttttca ttgaatccac ctcatttatt
    19261 atttgttata tctattatgg aacaaaagag aaaaaaaggc tagttttacg tttgtttgta
    19321 aacctttgca aaaaatcctt gaaaatgttt actaaatgtt ttattataaa tttaccatat
    19381 gaatttacga aattttactt tgtttgtttt caccataaaa gtaaacttcg ttttttaaat
    19441 tatatagaat caacaaacac aattttacta atcaaaggag tgttttttat gacaatttta
    19501 gtactaggcg gagccggtta tatcggttcg cacgctgtag accagctagt tcaaaagggg
    19561 tatcaagtag ctgtggtaga taatttgctc acaggtcaca aacaagcagt acatccagat
    19621 gctcattttt atgaaggaga catccgggat aaagaatttc tacgttccgt atttgaaaag
    19681 gaaccgattg aaggagtaat ccattttgct gcaagctctt tagtaggaga atctgtcgaa
    19741 aaaccattga tgtatttcaa caacaacgta tacggtatgc aaatcttact tgaagtcatg
    19801 cacgagttca acgtgaataa aatcgtattc tcttctactg cagcaactta tggagagccg
    19861 aaagagtctc caatcacaga agatacacca gctaatccta aaaatccgta tggtgaaagt
    19921 aaattgatga tggaaaaaat gatgaagtgg tgtgaccaag catatggcat gcgctatgtc
    19981 gctttgcgct acttcaatgt agccggagca aaagcagatg catctatcgg agaagatcat
    20041 acaccagaaa cgcatcttgt cccaatcatt ttacaagtag ctcttggtca aagaaaagcc
    20101 ttggctgttt atggagacga ttatgataca ccagatggaa catgtatcag agattatgtt
    20161 caagtagaag atttgattgc tgcacatatt ttagctttgg aatacttgaa agaaggaaat
    20221 gaaagcaact tcttcaattt aggcagcagc aaaggatact cagtcaagga aatgctagaa
    20281 gcagctagag aagtgacagg aaaagaaatt ccagcagaaa tagcaccaag aagagctgga
    20341 gatcctagcc gattagtcgc ttcaagtgaa aaagcgagag agattctggg ctggaaacct
    20401 gaatacacag atatcaaagc gattatcaaa acagcatggg attggcatgt cagccatcca
    20461 aatggttatg aagaataggg gaatgagata tgtcaatcag tcaaacgatt tgtgattttg
    20521 ccacacttgc gatcgaagct ggcggatgga tggaaatgga ccgcttatat ttacagaatc
    20581 gtcttttagg gatggtagga gaagatgctc tagaaagcat tgaagtaaga ccagttaagg
    20641 aagaatctgt agacttattg gatcagcttg tcgctaaggc aagagaaaat ggtgttcttt
    20701 cagaattgcc agcagaacaa gagatttttg aagcgcaatt aatggatttt ctcacaccgc
    20761 caccttcagt cgtcaatgca ttctttgcac agcactattc gaaaagccca gaggaagcaa
    20821 ctgagtattt ctttaattta agtaagaaaa atgactacat caaaacaaga gccatcgcaa
    20881 aaaacatcaa atttccggca gagtcggagt atggtgaact ggaaatcaca atcaatttat
    20941 ctaagccaga aaaagatcca aaacaaatcg cagcagaacg cgaggcggta aaagtagact
    21001 atcctacctg catgctttgc atggaaaacg aaggatatag aggtcgcttg aactatccag
    21061 cccgcaccaa tcaccggatt attcgaatga atctagacgg tgaaagctgg ggattccaat
    21121 attcccctta tgcttattac aatgaacatt cgatcatttt atcagaacaa caccgcccga
    21181 tgaaaatcac aaaggaaaca tttgctagac tgcttcggat tactgaagtc ttgcctcatt
    21241 actttgttgg ttcgaatgct gacttaccaa ttgttggagg atcgattctt tctcatgatc
    21301 attatcaggc aggacgtcat gaatttccta tggcaaaagc accgatagaa aaacttatca
    21361 aactagaaga ttatccgcaa gtcatcgcag gagtcgtgaa atggccgatg tctgtgatcc
    21421 gtttgcaatc aacagagaaa aacttgctta ttgaagcagc taactcagta ttggaaaaat
    21481 ggaaagcata ttcggatgaa acagtatcta tcagagcttt ttcagcagat ggtacaccac
    21541 accatacgat tacgccaatt gcacgaagaa gggacaatta ctttgagttg gaccttgtcc
    21601 ttcgagacaa caatgtttca gaagaacatc ctgatgggat ttttcatcca cataaagatg
    21661 tccaacatat caaaaaggag aacattgggt tgatcgaagt aatggggctt gctgttttac
    21721 cacctcgttt gaaaccagaa ctagtagaag tagagcattt cttattagga gaagaaaacc
    21781 agatggctga atatcatcgt ccgtgggcag aacaattaaa aaaagaacat cctgatttga
    21841 cgaaagatac ggtcaccgat gtcgtacaaa aatctgtagg tcaggttttt gcacgtgtac
    21901 tggaagacgc tggagtattc aagcgagatg aaaaaggaca ggcagcgttt gaacgattta
    21961 ctgcgatttt ataaacgtaa aaaaggagga gagacaaatg gcaacaatta aagacattgc
    22021 gcagttggca ggagtttctc ctgctactgt ttcaagagtt ctcaactatg atcctgatct
    22081 ttccgttggc ttagccacaa agcaaaaaat ttttgaagca gcagaacgct taaattatac
    22141 gaaacatcgt aaaaatgcag caaatactaa gcaaacgctt cgcctgatcc agtggtacga
    22201 cgatacggaa gagcttgaag atctttatta tttatctatt cgcctaggaa tcgaaaaaaa
    22261 ggcagaagaa gcaaacgtta ctttattgaa agaaacgtgg gattccatta gtgatcttcc
    22321 ggcagatgga acgatcgcac taggaaaatt cgacgaagct cagttattag aaatgaaagg
    22381 atcccaaaat gccttgcttt tggtagattc tgacggcact tctcaaggaa tcgactctct
    22441 agttgtcgac tttaagtcaa gtgttcaaaa agtcattgaa cactttgtct cccataaagc
    22501 gcaacatatc gctatgcttg ctggaacaga atatacgaag aaaaaccatc agcggctaaa
    22561 agatcccaga attatggcat ttcaacaagt tttggcagaa aaaggctacg acgaaggtcc
    22621 aattatcgaa gcagattttt ctgtcgagtc aggatatcaa gcagtgaagc agtatttaaa
    22681 aacgaatccg catgttcctg atgcgctttt tgcagctaat gatgcattag cgattggcgc
    22741 actgaaagcg attcaagaaa aaggtttagt ggtaccagaa gatatttctg tgatgggctt
    22801 caatgatgtc agtgtagcga aatatgtaac gccctcgctt tctactgtaa aagtttatac
    22861 cgaatggatg ggagagctag cagtggagac gattcttcaa ttaagtaatt ccaaagcacc
    22921 ggtttcaaga aagattattg tggaaacaga gttgattatt cgagaatcaa cgaaataaaa
    22981 gatggaaaag ctgtgggaaa atggagtgat accgcagctt ttttgtgttt caggaagggg
    23041 caaaatttgc ccgccagcag ataatcatgt atcattgtac tagttttgcc tttggtattt
    23101 tcatcctcag aataaaaaag tatgctacaa tggaaggcga gaatgtcata gcagaaagga
    23161 tcaaatatat gattacatta ggaatagata ctgcaaacca aactttggcg atcggtgtgg
    23221 tagaagacga acaaattctt ggacaaatac aaacaaatat caaacgcaac cacagtgtaa
    23281 cactgatgcc tgcaatcgac caattgtttg cagatcttca aataagtcca aaagacattg
    23341 accgaatcgc ggtttctgat ggtcccggtt cttatacagg gcttcgtata ggtgtaacga
    23401 cagcaaaaac gattgcttat acattagata aagagctagt aggagtatct agtctgaaaa
    23461 ccatcgcggc taattgcatc ggtgtggata aaattattgt gcccatgttt gatgctcgaa
    23521 gaaaaaatgt atacgctggg gcataccgct ggaaagaaaa tagattagaa attgtacttg
    23581 aagatgtaca tatttctgct tctgatttgt tcacacaact acaaaagctg aatgaagcta
    23641 tttatttcgt cgggagtgat tgtcacaaat tcttctatga aataaaggaa atattgccta
    23701 gtgcgatgat taatacagtt ccagcatggg atattccaag tggtgtaact gtggctcaat
    23761 taggtgcttt agctgaacca gttgcagaga aacaagcttt tcttcctcgc tatttaaaac
    23821 gggtagaagc agaagaaaaa tggttggaga cgcacacacc tggagacgaa agttatgttg
    23881 aaaaaattta gagcgtatgc cagaagcttt tttcaagata aaatgattta tacagaaaaa
    23941 acaatcgaac aaatcgatcg tcgttacgta ctaagagaat tgactacaga agatatcaaa
    24001 gagctgctgg atgtcgaacg agaagtctat aatggcgaat tgccatggac aaaaagtgcc
    24061 tttatatcag aattgaagtc accgcttcct catctatatc taggtatctt tgataatgga
    24121 agaatgattg gttttatcgg ttcaagagcg ttcggtttag attgccatat cacgaatatt
    24181 gccgttcgac cggcatatca gcgtaaacga atcggttcgc tgcttattga cgaaatcgag
    24241 aactttgcta taatgaatcg ctgtgagacg atgtcattag aagtgcgtat gagtaatcaa
    24301 gatgcacaaa gactttatcg gaagttaggt tttcaagcaa caacgatcaa aaaaagatat
    24361 tacactgaaa caaaagaaga tgcgttggat atgataaaac ttttagaaaa tgagtgagat
    24421 tagttgattt gcagaaaaaa agattttgat gaagcgtact tggcagaatg cgtatggatg
    24481 attagcgaaa atgcttatcc acatggttca ccttggacga aaatgcagtt tttggcagac
    24541 atccaacagc ctcactctga ttatctgctt ttagttgaag ataaccagat ctgtggcttt
    24601 attggatact cgaaagtaat agatgaagtc gagatcacaa atattgctgt tgcagtttca
    24661 gaacaaggaa aagggcatgc acggcatttg ttacaattac tgattacgga acaaataaaa
    24721 gattcgctgc atgttttttt agaagtacgt ctatctaatg aagcagcaag aaaactttat
    24781 gaatcagaaa agtttcgtat attaggtaaa cggaaatcat attatcgcaa tccgacggaa
    24841 gatgcgatca ttatgagcag aaagttaaaa acggagacga tgaaatgaat gaagaattga
    24901 ttctggcgat tgaatcaagt tgtgatgaaa cgagtgtagc ggtcgttaga aatggaacag
    24961 agatcttatc taacatcgtt gcttctcaaa taaacagtca taaacgtttt ggtggcgtag
    25021 ttcctgaagt agctagccgc catcacgtag aacaaatcac cttatgcttg gaagatgcac
    25081 tggtagaagc tggtgtgtcg gcagaagatt tatcggcagt cgctgtcact tatggaccag
    25141 gacttgtcgg ctcgttgctg attggtattt ctgcagctaa ggcttttgct tgggcacacc
    25201 aattgccgct tattcctgta aaccatatgg cagggcatat ctatgcagcc cgtctggtta
    25261 aaccattcca gtttccattg atggcacttc ttgttagcgg aggacataca gaattagtct
    25321 atatgcaaga agatggatca tatgaaatca ttggggagac aagagatgac gcagcaggag
    25381 aagcttatga caaagttgga agagtattag gtctttctta cccaagcgga aaagaaatcg
    25441 atcagctagc tcatcaggga aaagataatt accattttcc acgagcgatg atccatgaag
    25501 ataattatga tttcagtttt agcggattaa aaagtgcatt tatcaatttg gtgcataatg
    25561 cacaacagcg tggagaagat ctagacaaaa atgatttagc agctagcttt caagcaagtg
    25621 tgatcgatgt attgattact aaaacacttc gagcttgtca aaattatcca gtcaagcaac
    25681 tgattgtagc tggaggtgta gcggccaatc aagggttgcg tgaaggattg caggatgctt
    25741 tggcaactaa actccctgag gtagaactag tgattccccc tcttcgactt tgtggagata
    25801 atgctgcaat gattggagca gcagcacatg tggaaatgca aaaaagaaat tttgctagct
    25861 atcagttgaa tgctgatcca agcttggttt tatctgaata aagaggttgt gaaaaatctg
    25921 ccctgcatca agtaataaga acagcccagg aaaaacggct tctcatgttt ttgacctggc
    25981 tgttcttatt accgcgtatg caagcttttg aacgccgttt aatcaagagt tcgtaagcct
    26041 gtcgtttaac tctgattcac aaggaacaat ttcaaaaaac agctcctcat gtttatgaac
    26101 attatgactt gtgaccgaag agttgacagg tacacaccgt ttaatcgaaa taagggctgt
    26161 gacacgcttt tgtcaaagcc ctatttttta cagcttattc atcattatcc gttcctctga
    26221 ttgccctcac tgattaatcg tttattgtcg aggaatatcg aataatctag gtcggatgag
    26281 gacaagacgc ttcctctagt taatctatca gtattttttg caaacagtga atattacata
    26341 actgaaacac acatagaaaa tctttgagtc ttgcccagtg atctaaaact gccggatctt
    26401 tcagaagttt tagggaggaa aataagcagt gaccctgata aatatcaggg tcactgctta
    26461 tttttgttcg cgttattctc tcatagctgg agtagtagct gtcttacaga aagtaaaacg
    26521 ctttttgtca taatctaaca gtccggaatc acgtagttgt ttgattactt gtccagcagt
    26581 ttcacgtgtc gtgccgctat tcactgctaa ttcttttaag gtgatcggat aaggaatggt
    26641 gatatgacca tcttttgttg gtacgcccaa ttcttctttc aaaatgaata aattttgttt
    26701 tacccggtca aaggcgctag aggtcaatcc gatttggata cgcaattcat gtatttcaac
    26761 tactttagaa attttttgta tcatatagat caactgttcg ggattttttc gtgctaattt
    26821 ttcatagtag gaaacaggaa ggtagaatgt ttcaatatca gtcatcgctt gagctgtata
    26881 agtgtaggtc tcttctccaa acattcctga cataggaaaa aggttatttg tattcacata
    26941 gtcatagtag taataagttg cactttcatc ataacgttct aaacgaacga gtcctttggt
    27001 caagatatac aaccgttgtc tgggatcacc atcgtcgaaa aggatctgtc cttttttata
    27061 agaacgaaga acagtatgtt ccttgatctg ttggaactct tcatccgaga aatgttcaaa
    27121 atcaggttga tatctgagtt ttgaaaagtg aaaatcgatt ttattaacac gcattaaaaa
    27181 gtcctctcct tattgttcac tatatttatt gtcacttttt ttaaagaatt tgtaaagttt
    27241 taacatacca acattagaaa caagttttaa tactttacaa atataatttg ttattatgta
    27301 aaaaatatac aatggtattg aataatttgt tttgaagcga atgatt
//
LOCUS       DAZKKZ010000039        27232 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.039, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000039 DAZKKZ010000000
VERSION     DAZKKZ010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 27232)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27232)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27232
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.039"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(161..445)
                     /locus_tag="ACG8LA_001763"
     CDS             complement(161..445)
                     /locus_tag="ACG8LA_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204060.1"
                     /translation="MKYYDVTFHELSGKTVVKRDIPSEKNGFDVWKDACADYNENELF
                     ILINDGAYVTMNRKFIVRIDTEEVEDPTEKARSRKDEIMGVVNTLSNMGF"
     gene            complement(463..1353)
                     /locus_tag="ACG8LA_001764"
     CDS             complement(463..1353)
                     /locus_tag="ACG8LA_001764"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YicC/YloC family endoribonuclease"
                     /protein_id="HFQ0204061.1"
                     /translation="MKSMTGFGKAIRETKAYQLDIEIKSVNQRFLDVQIRSPKILNFV
                     ENDFRQLIKQQLSRGRIEVFVNLAYIGKNEKQIVINWELIDSLITQLTDGIQQRYGSQ
                     NQVSISRMAERFALDENFVTVEEKPEESMEELAQLALDTLKSALDSIEASREKEGQAL
                     ALVLKKNTEEFKEVLKKLDSFVEIYEKEFQIRYQKKLEEFLGAKVDEQRLLTELAILL
                     ERGDIHEELDRLAIHVQKLDELIEAQCPVGRELDFLIQEMNREINTIGSKSNAIEIKN
                     QVVQSKTILEKIREQVQNIE"
     gene            complement(1373..1591)
                     /locus_tag="ACG8LA_001765"
     CDS             complement(1373..1591)
                     /locus_tag="ACG8LA_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HFQ0204062.1"
                     /translation="MAQEFSYEIVEEIAILSENNKGWRKELNLVSWNGRPPKFDLRDW
                     APDHEKMGKGLTLTNEEFEQLQKAIENM"
     gene            complement(1561..3261)
                     /locus_tag="ACG8LA_001766"
     CDS             complement(1561..3261)
                     /locus_tag="ACG8LA_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HFQ0204063.1"
                     /translation="MEIKKVYFSQKMSLYSPIQQAKQPLPFFQSHQESRDAFWRSAKK
                     QCAFKAVSKKYTVYFTIAKSRGDVIFNNLLIEGETFEWKKFFRYMEACARFFIKENCC
                     FLFQSPLSEEWLRIFHKNGYQGTTQLNKKLVYHTALVLGGGGAHGAYQIGVWQALKEH
                     DINFEIITGTSVGALNGALILQGDMKKAVNLWKKLSTRQVLALPEMAAVEDLRERFYR
                     ERRQMTKTALIEGGVSSAPLEKMVKDNLDLSLLKHNPKIRLYTVSTKLPELAEVVTDI
                     QQTKTEEIPDWILASASFYPAMAYRKIGKNKYADGGYRNKIPIDIAINKGATEAFVVD
                     VQGPGPAKKIRMPDIFIHWKCQTLWTLGSFLLFDSQRNQLNLQLGYLEMKKRLGYYYG
                     NWYTFHSVKPARTYWRGFLSYLTKEIQLELSFFKSIKFWQKLRNLYKNRVVPETCGLA
                     MLELLAKKHFLLPNEIYQVDMMIQMICQQDIKSMPDDLLAQIGQLSTEEWRRYRKYQQ
                     KIQNERTKTVYFDYLLQGKRKDRLQHELLKQPVDTLLILYLYYLKEEQPWHKNFHMKS
                     "
     gene            3528..4301
                     /locus_tag="ACG8LA_001767"
     CDS             3528..4301
                     /locus_tag="ACG8LA_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204064.1"
                     /translation="MTESVYVHIDTTSNAVLTKGLTATDFANSIVHFPQNLLLLDPSA
                     SAGEYESHTGLKVIRGTENIQRFFSSSRNRRGFDELKWIDFTDLTMLKELTPLEISEL
                     LYFGHMKTHLHSPFFYKLQNNFVYFDLNDQLNRIYYRYLDEFYRIFASKLSSILSDKI
                     NVKKSFFKKETPVEKISVELLKEMRNLMQEGIIFSFDQVGLIDGKYRIPIYVIEDYIW
                     KLKGTRYREEEIIATLIYSVTDRHWQLVEDADLSYLPLK"
     gene            complement(4382..4951)
                     /gene="thiT"
                     /locus_tag="ACG8LA_001768"
     CDS             complement(4382..4951)
                     /gene="thiT"
                     /locus_tag="ACG8LA_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015234 - thiamine transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015888 - thiamine transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupled thiamine transporter ThiT"
                     /protein_id="HFQ0204065.1"
                     /translation="MGKNRVWVEGTIVAALAMVLSLIPIQIGSSFSISLGQIPLTLFA
                     LRRGTKAGMLAGFIWGILHFPLGQVYYLSVVQVLIEYPIAYTFAGAAGLMASNVQKGY
                     VDDNTKQIRKSIVFGALIGALSRYFWHFIAGVVFWGAYALWGMNPWLFSFVMNGASGL
                     STAIVTIIVLLGIQQTTPSIFVPDKRQEL"
     regulatory      complement(5017..5119)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(5125..6096)
                     /locus_tag="ACG8LA_001769"
     CDS             complement(5125..6096)
                     /locus_tag="ACG8LA_001769"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016618611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004749 - ribose phosphate diphosphokinase
                     activity [Evidence IEA];
                     GO_process: GO:0009156 - ribonucleoside monophosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HFQ0204066.1"
                     /translation="MSKHYFDPRLKIFALNSNRPLAEKIAAAVGVELGKSSVTQFSDG
                     EIQVNIEESIRGSHVYVIQSTSSPVNDNLMELLIMIDALKRASAKTINVVMPYYGYAR
                     QDRKARAREPITAKLVANMIQKAGATRMLTLDLHAVQIQGFFDIPVDHLMGAPLIANY
                     FLEKGIKGDDVVVVSPDHGGVTRARKLAEFLKSPIAIIDKRRPKANVAEVMNIIGQVK
                     GKTCVLIDDMIDTAGTITLAANALKEAGATSVYASCTHPVLSGPALQRIEDSAIERLV
                     VTDSIYLPEDRKIDKIDEVSVGGLMGDAIKRIHENKPVSPLFETKNK"
     gene            complement(6190..7563)
                     /gene="glmU"
                     /locus_tag="ACG8LA_001770"
     CDS             complement(6190..7563)
                     /gene="glmU"
                     /locus_tag="ACG8LA_001770"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0003977 - UDP-N-acetylglucosamine
                     diphosphorylase activity [Evidence IEA];
                     GO_function: GO:0019134 - glucosamine-1-phosphate
                     N-acetyltransferase activity [Evidence IEA];
                     GO_process: GO:0006048 - UDP-N-acetylglucosamine
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HFQ0204067.1"
                     /translation="MDARYAIILAAGKGTRMKSKLYKVLHPVSGKPMVEHIINRVSET
                     KPDEVITIVGHGAEQVKAQLGERSKYALQAEQLGTGHAVLQAASFLEGKKGTTLVISG
                     DTPLLTTETLNNLFEYHQGKNASATILTAQAENPTGYGRIIRDHIGIVEKIVEQKDAT
                     PEEALVQEINTGTYCFDNEALFDALSKVGTNNAQGEYYLTDIIEILKEEGHTVAAYQT
                     DDFEESMGVNDRIALAKANEIMRKRINQMHMVNGVSFVDSATTYIDAGVEIGPDTLIE
                     AGVQIQGNTVIGSDCVIGSHSKIVDSRIEDHVVIENSVIESSHVKKHADVGPYAHLRP
                     KAEIGENVHIGNFVEVKNAQIGKGTKVGHLTYVGDATLGEEINVGCGVVFVNYDGKNK
                     HHTTVGDHSFIGSSTNIIGPVEVAKNSSIAAGSTITDNIPEYALAIARARQVNKEGYA
                     KKLPYLN"
     gene            complement(8066..8884)
                     /gene="purR"
                     /locus_tag="ACG8LA_001771"
     CDS             complement(8066..8884)
                     /gene="purR"
                     /locus_tag="ACG8LA_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA];
                     GO_process: GO:0045982 - negative regulation of purine
                     nucleobase metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HFQ0204068.1"
                     /translation="MKVRRSERLVDMTQYLLNHPHELISLTSFAERYESAKSSISEDL
                     GIIKKTFKERGYGTLETIPGAAGGVLFIPEISYEEAKKYIESLAERLSEQDRLLPGGY
                     VYLSDLLGEPELLRQVGRIIASKYLGEKIDAVMTVATKGVPIAQAVSYYLNAPFVIVR
                     RDSKITEGSTVSVNYVSGSSERIEKMELSKRSLKRGSRVLVVDDFMKGGGTVNGMKSL
                     IEEFESELVGITVFAESKFNGHRAIDDYTSLLYVKDVDTQTKNITVVPGNYFSE"
     gene            complement(9051..9875)
                     /locus_tag="ACG8LA_001772"
     CDS             complement(9051..9875)
                     /locus_tag="ACG8LA_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HFQ0204069.1"
                     /translation="MALLSYEFMRRAFLAAIFIAGIAPMLGVFLVIRRQSLMADTLSH
                     VSLAGVALGFFLNLNPTLTTMLVVVLAAVILEYLRTIYRTYSEISIAILMAGGLALAL
                     VLMNLSGGNSATSIQSYLFGSIVTITWEQVIFLGILFVAIGILFFLFKRPMYVLTFDE
                     DTAHVDGLPVHLMSMMFNVITGVAIAVMIPIAGALLISAIMVLPAAIGMRLGKSFNVV
                     IAISVCVGFLGMLSGLTSSFYLDTPPGATITLVFIALFLIVNIIKRILVAFRRKNN"
     gene            complement(9848..10528)
                     /locus_tag="ACG8LA_001773"
     CDS             complement(9848..10528)
                     /locus_tag="ACG8LA_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HFQ0204070.1"
                     /translation="MRYIEISDLTFYYDDEPVLEDVSYHVDAGEFVILTGENGAAKST
                     LVKASLGLLKPSKGMIKIAEKNQEGKKLSIGYIPQQVASFNAGFPSTVIELVRSGRYP
                     RGRWFKRLSEKDHQHVQRALEAVGMWDMRNRRIGELSGGQKQRISLARIFATDPDLFV
                     LDEPTTGMDEESRNEFYRLLRHSAHVHGKSVLMITHDHEDIKQYADRQIRLVRKEDSQ
                     WRCFHMNS"
     gene            complement(10551..11489)
                     /locus_tag="ACG8LA_001774"
     CDS             complement(10551..11489)
                     /locus_tag="ACG8LA_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HFQ0204071.1"
                     /translation="MKKYLLTATVMIGALLFAACGNTNKEADKKEDLTIVTTFYPMYD
                     FTKEIVGDEGNVKLLIPAGTEPHDFEPSAKERAEISDADVFVYNSSDMEFFVDSLKDS
                     VDSKQTLMIEAAKGIDRLESQEADEHEESEEGHGHSHEYDPHVWLDPVLAIKEVRTIA
                     EELGEKYPDKKETFTKNADAYIKKLEALDQKYSDELKDATNRTFVTQHAAFAYLANQY
                     DLKQVAISGVSPDQEPTPSRLAELKEFVKKNNIKVIYFEENASSKVAETLSNETGVKL
                     EVLNPLESLTNEQIKAGENYISVMEKNLKALKESIN"
     gene            complement(11734..12585)
                     /gene="ispE"
                     /locus_tag="ACG8LA_001775"
     CDS             complement(11734..12585)
                     /gene="ispE"
                     /locus_tag="ACG8LA_001775"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050515 - 4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase activity
                     [Evidence IEA];
                     GO_process: GO:0016114 - terpenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HFQ0204072.1"
                     /translation="MELIEKAPAKINLGLDVLYRRQDGYHELEMVMSSVDLADHLFFE
                     EITEDKIIVETNKAFLPVDERNNVYQAALLLKNKYNIKTGVKIFVKKNIPVAAGLGGG
                     STDCAAALRGINQLWNLGCSLEELAEIGLEVGTDVPYCVYGSTAFVGGKGEEIQVLPS
                     MPQCWVVLVKPRMSVSTRTVFREVDTQAIQHQDIHGLAEAIREQDYQQMIKKMGNSLE
                     DITGKRHPVIHQIKERMIKYGADAALMSGSGPTVFALCQHYSRAQRVYNGLKGFCEEV
                     YLVRTLQ"
     gene            complement(12739..15312)
                     /gene="mprF"
                     /locus_tag="ACG8LA_001776"
     CDS             complement(12739..15312)
                     /gene="mprF"
                     /locus_tag="ACG8LA_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HFQ0204073.1"
                     /translation="MKNKRYLMLQWIKEHSLILKLIFFGSVLVFVANQVANIANGMSW
                     QDIWQRMGQQSRMTILLMILAGLLGVTPMLLYDWVTIRVLEKQGKPKMERKEFLLAAW
                     VTNTINNLAGFGGVVGASLRASFYGKQTNRKMVLATVSKVALFMLTGLSVWSFLTFID
                     VFFIQSESIFRSYWIWLFGGSFLAPVIFFFAYLKRKTLFFEFYPKGLLGLLLASFGQW
                     TGALAVFLIIGKLMRIDISMLSIYPMFMIATLIGMLTMVPGGMGTFDVLMILGMSQLP
                     VRQDVAVVWLLYYRLFYYVLPFMTGLLLFITHTGVKINRFLDNIPRLFFQKVAHIVLV
                     SAVYFAGIMMVLLSTITNLSAISRLFQVLLPFSFNFLDQTVNLLVGFLLLGLARALSV
                     KVKKAFLPTIALLSFGILNTITRTLSWQLILVYVLILLAVWLSRKEFYRTKFVYSWGA
                     IIFDASLFGFLFIVYAIAGYHSGRFLVGRITGNHFILFPSDDVWFSGLIGLGISLLAL
                     VALYQYLAEDTTKLGSEYEKDRFDRLLETYGGTATSHQLRLSGYSYFYYQEDDQDQVV
                     FGYQIKGNKCFVLGDPVGNPKMMRAATNQFMKQADCLGYQLAFYKISESYVVMLHELG
                     FHFTKVGEAGIVDLATEDLSRLSQQLEYQRLMKEGYHFTWYDQLPEELHQAVNEVSQK
                     WLQGAREKYFSVGRFDKSYVLSSGVGIVRKDQKVVGFITAQPMTKKQAGYDLLRVLPK
                     ESEELADYLLANLFIVYEKMGYSEANLGLAPLANVGETDFSFFQEKVMHIVYNYGNFF
                     YSFQSAYEKKLKYVDHWEGRYFAYRKGSNFGFATMQLLSLIGKEKGNVPSLAEEVLTE
                     L"
     gene            15453..16259
                     /gene="proC"
                     /locus_tag="ACG8LA_001777"
     CDS             15453..16259
                     /gene="proC"
                     /locus_tag="ACG8LA_001777"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004735 - pyrroline-5-carboxylate
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HFQ0204074.1"
                     /translation="MKVGFIGTGNMAQAIIDGLLKKGTVSKEEVFVSSGHFENAQKFA
                     AETGVHACKSNQEVASQSDIVLLAVKPKIIEKVLEELREYSQKVLFISIASGKSLTDL
                     ETALEDPQASIVRVMPNVNVSVGAGVSAICKNEAATEEQLQQATMIFEAIGSVYPLAE
                     SDFSTFIGLAGSSPAFVYMLIDAMGRTGVLNGLSKQTATEIAAKAIMGSCQKFLSSDK
                     NPWELVDQVSSPGGTTVAGVVALEEAGFIPAIIKGINTTIEKDLEMLNKK"
     gene            complement(16338..17894)
                     /gene="rny"
                     /locus_tag="ACG8LA_001778"
     CDS             complement(16338..17894)
                     /gene="rny"
                     /locus_tag="ACG8LA_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006402 - mRNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HFQ0204075.1"
                     /translation="MVFNILLAIIGLIVGLGLGFMVAKSRHEKEIAGAQSSAAGIIDS
                     AKKEAETLKKEALLEAKEENQKYRSEVESELRESKLELKSQENRLIQREQTLNRKDDS
                     LEKRENSLESKEEALSSKQQLIEEREKDVEKMIEDQQKELEKIAGLSKEDARDVIMKS
                     TEEELNHELTLMVKESEQRAKEEADRKAKNLLSLAIQRCAADQVSETTVSVVTLPNDE
                     MKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVVLSGFDPIRREIARMTLEKLIQDGR
                     IHPARIEEMVEKSRKEMDERIREYGEEAAFEVGAHTLHPDLIKIIGRLRFRTSYGQNV
                     LKHSVEVAKLAGILAAELGEDIQLAKRAGLLHDIGKALDHEIEGSHVEIGAELAAKYK
                     ENPVVINAIASHHGDVEATSVISVLVAAADALSAARPGARSESLENYIRRLRSLENIS
                     NSFAGVESSYAVQAGREVRVMVKPEEISDLDAVRLVRDIRKRIEEELDYPGHIKVIVI
                     RETRATDYAK"
     gene            complement(18305..19354)
                     /gene="recA"
                     /locus_tag="ACG8LA_001779"
     CDS             complement(18305..19354)
                     /gene="recA"
                     /locus_tag="ACG8LA_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008094 - ATP-dependent activity, acting
                     on DNA [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HFQ0204076.1"
                     /translation="MADDRKAALDAALKKIEKSYGKGSIMKLGEKIDQQISTIPSGSL
                     ALDVALGVGGYPRGRIIEVYGPESSGKTTVALHAIAEVQKNGGTAAFIDAEHALDPQY
                     AQKLGVNIDELLLSQPDTGEQGLEIADALVSSGAVDIVVVDSVAALVPRAEIDGEMGD
                     SHVGLQARLMSQALRKLSGSINKTKTIAIFINQIREKVGVMFGNPEITPGGRALKFYA
                     TIRLEVRRAEQLKQGTDIVGNRTKIKVVKNKVAPPFKIAEVDVMYGLGISQEGELLDM
                     AVEKDIVDKSGAWYSYKEDRIGQGRENAKIYMANHPEMMAEVSALVRAAYGIGEEVAV
                     PEDEKGQEELPLVEE"
     gene            complement(19463..20704)
                     /locus_tag="ACG8LA_001780"
     CDS             complement(19463..20704)
                     /locus_tag="ACG8LA_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HFQ0204077.1"
                     /translation="MKAEIIAVGTELLLGQVVNTNATFLSEQLADLGIEVYYQTVVGD
                     NQQRLEELIALAETRSELILLCGGLGPTEDDLTKEATAAHLGKSLIQNTEGYKKLLAY
                     FETTHRKMTKNNLQQSQIIEGGVPLPNRTGLALGTFYQTDTHAYILLPGPPNELKPMF
                     VEQVRPLLEERFPSEEKLISKVLRFYGIGESRLVTELKDLIETQINPTIAPYAKPNEV
                     TLRLTVKTNDVQAGNQALLALEEKIQERVGEYFYGYGDDNSLAKVVVELLKENKQTVT
                     AAESLTAGAFQAALGDIAGVSEVFPGGFVTYSLQTKAGFLEIDPELLAEYGTVSKECV
                     EQMAIQAREIARTDYSVAFTGVAGPDTLEGQSAGTVWIAISSKDGVVSEKYHFARDRA
                     AIRYNAVMQGFDLLRKQLLRK"
     gene            complement(20944..21522)
                     /gene="pgsA"
                     /locus_tag="ACG8LA_001781"
     CDS             complement(20944..21522)
                     /gene="pgsA"
                     /locus_tag="ACG8LA_001781"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008444 -
                     CDP-diacylglycerol-glycerol-3-phosphate
                     3-phosphatidyltransferase activity [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HFQ0204078.1"
                     /translation="MNLPNKLTVLRICMIPIFILVVGLPLDWGQFNVGDTTLAVTQLV
                     GAVIFALASITDWLDGKIARARGLVTNFGKFADPLADKMLVMTAFIMLVDQGKAPGWV
                     VAIIVCRELAVTGLRLLLVEHGEVMAAAWPGKVKTATQMVAIILLFINNIPFSLIGIP
                     VDQIMLYACLIFTIYSGVDYFIKNSGVFKGSM"
     gene            complement(21731..22654)
                     /locus_tag="ACG8LA_001782"
     CDS             complement(21731..22654)
                     /locus_tag="ACG8LA_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RodZ domain-containing protein"
                     /protein_id="HFQ0204079.1"
                     /translation="MLRRIKQTGEDERVAFETIGEKLRQARLNKKISLDELQQITKIQ
                     KRYLEAIDNDDFDQLPGKFYVRAFIRQYAEAVGEDGDHLVDVFDGKSKLTGSVPERPQ
                     PETVSTSRKAMHQEESHPSRFWTSLPVILLGLVALAIVVVVGYMTWQDRQADPIIGDT
                     ASSLKVEGSVEESSSSEQSTQTKESSTVESTTKSSEEKKMAIATGEDSGSAIAVNITD
                     ATKPVTLEFTAVNRVWLGVLVDNAYVYQGTLAANETQSTVLPETATNATITIGAASNA
                     TIKANGESVPVNPGENNQSPKNVNLTLQYAE"
     gene            complement(23392..24678)
                     /locus_tag="ACG8LA_001783"
     CDS             complement(23392..24678)
                     /locus_tag="ACG8LA_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M16 family metallopeptidase"
                     /protein_id="HFQ0204080.1"
                     /translation="MNKTEYEQINETLYHEVLPNGLTVYLLPKNDYHKTYGLFSTNYG
                     SIDNEFIPYGEKEKVKVPDGIAHFLEHKLFEKEDGDVFQLFGKQGASANAFTSFTKTS
                     YLFSTTDQVEKNLTTLIDFVQAPYFTEETVNKEKGIIGQEIQMYEDDPNWRMFFGILN
                     NLYPTHPLHIDIAGTVESIDKITAQDLYTCYRTFYQPSNMVLFVVGKMEPEKLMKLIR
                     ENQEAKNFPPKQEIVRYFPENTKEIIKQSALEAAITRDKFVLGIKGLDTLPQEGTELL
                     RYKTAINLLFQMILGNTSRNYLAMYNQGIIDDSFGFEFSLDREFHFADFSGDTDEPEK
                     AAEKVKEIILGFADDPEVSETNLDLLKKKMLGQYFQSLNSIEYIANQFTQSLFGDRTL
                     FDLPEIIDSIQMKDVLAAGEAFISEEAFSEFYMRPK"
     gene            complement(24671..25939)
                     /locus_tag="ACG8LA_001784"
     CDS             complement(24671..25939)
                     /locus_tag="ACG8LA_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M16 family metallopeptidase"
                     /protein_id="HFQ0204081.1"
                     /translation="MVYQLAEGVNLHVLPTKQYKTIRIFIRFTARLQQEVITKRSLLS
                     SMLETNSLNYPDQTKLSAQLAELYGASFGLSVRKKGNLHWLNAGISFVNGEYVNDPNL
                     FSQAVDFLKEVLFYPNIKNHQFDQLTFDLEKNNLRLYLESLKEDKQTFASYALQELYF
                     ENSPEQKIPGLGVVEDLDKITASSLASYYQEMMANDQIDIFVVGDVDPDKAAEAVGQL
                     PFESRETVYPDLFYTQPQVNIVKERQVREPIVQAKLNLAYQTNVYYDEPERFALMVFN
                     GLFGGFPHSKLFMNVREKESLAYYASSSVDTFRGFMSVQTGIDEKNRNQVLHLIHEQL
                     ESLRNGEITELELSQTKAMLRNQYLLSLDSPQAAIEASFLDSWLPETKLSDEEWLKRM
                     ESVTIKEIQQVAEQIELQAIFFLAGGNANE"
     gene            26191..26652
                     /gene="mscL"
                     /locus_tag="ACG8LA_001785"
     CDS             26191..26652
                     /gene="mscL"
                     /locus_tag="ACG8LA_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008381 - mechanosensitive monoatomic ion
                     channel activity [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HFQ0204082.1"
                     /translation="MIKEFKEFIMRGDVLDLAVGVVIGSAFTSIVNQVVQGLITPLIG
                     WFVAMITGTSDLEGALSILDWSPTKGVTFAFGNVISAIITFLITGFVLFLVVKAANRA
                     KNLRSKEEQVEVEETPTAEDYLSDIRDLLAKQVAEDNTHPVEQTNLSDTSK"
     gene            complement(26711..27157)
                     /locus_tag="ACG8LA_001786"
     CDS             complement(26711..27157)
                     /locus_tag="ACG8LA_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFQ0204083.1"
                     /translation="MEYQVKKFEELSTAEFYAIVKERIAVFVVEQQCPYQEVDDIDGQ
                     AWHTFFQDTDGKILAYTRVYEEAESIHFGRVLVHQDNRKDGLGRKIVQETINMIQKNF
                     PEKPIVIGAQEYLQAFYESFGFKAISDVYLEDDIPHIDMKKEQVAS"
BASE COUNT         7741 a         5873 c         4723 g         8895 t
ORIGIN      
        1 taataccgag aaaatggttt ttgaacatca cttattcaaa ataaaaaaag attgtgacac
       61 gaattttgtc acaaccttta aatgtattcc tagagcaaag aagctaagcg aagaaatcca
      121 attctgatta tttattgtat ttctttgttc agcatccttg ctaaaagccc atattggaca
      181 aagtattcac tacacccatg atctcatctt ttcgagaacg tgctttttct gtcggatctt
      241 ctacctcttc tgtgtcaatt cgaacaataa atttccgatt catcgtcacg taagcaccgt
      301 cgttgatcaa aataaacagt tcgttctcat tatagtctgc acaggcatct ttccatacgt
      361 caaagccgtt tttttcagaa gggatatccc gtttaaccac agtttttcca cttaattcgt
      421 ggaacgttac gtcataatat ttcattatct ctacctcttt cgtcattcaa tattttgtac
      481 ttgttctctg attttttcta agatcgtctt agactggacg acttgatttt taatttcgat
      541 tgcatttgat ttggaaccga tcgtgttgat ttcccgattc atttcttgga tcaggaaatc
      601 taattcccga cctacaggac attgtgcttc gataagttca tctagttttt gtacatggat
      661 cgccagacga tccagttcct cgtgaatatc tccgcgttcc aacaagatgg ctagctccgt
      721 caacaaccgt tgctcatcga ctttcgctcc aagaaattcc tccagctttt tttgatacct
      781 tatttgaaat tccttttcat agatttctac aaaactatcg agttttttta gtacttcttt
      841 gaattcttca gtattctttt tcaacactaa agctaaagct tgaccttctt tttctcgact
      901 cgcctcaata gaatcaagtg cgcttttcaa tgtatctaga gctaactgtg ccaattcttc
      961 catgctctct tccggttttt cttctaccgt tacgaagttt tcgtccagcg cgaagcgttc
     1021 cgccatccga ctaattgaca cttgattttg actaccgtat cgttgttgaa ttccgtctgt
     1081 caattgagtg ataagtgaat caatcaattc ccagttgatg acgatctgtt tttcgttttt
     1141 gccaatataa gctagattca caaatacttc gattcgaccg cggcttaact gctgtttaat
     1201 aagctgacga aaatcgtttt caacaaagtt caggatttta ggacttcgta tttgaacatc
     1261 tagaaaacgc tggttgacac tttttatttc aatatctaac tgatacgctt ttgtttcgcg
     1321 gatggctttg ccaaaaccag tcatactttt cattcgacag ggtccttcct cattacatat
     1381 tttctattgc tttttgcagt tgttcaaact cttcgttcgt caatgtcagg cctttcccca
     1441 ttttttcatg gtctggcgcc caatctcgaa gatcgaattt tggcgggcga ccattccagc
     1501 tgactaggtt cagttcttta cgccacccct tgttgttttc tgacaatata gcgatttctt
     1561 ctacgatttc atatgaaaat tcttgtgcca tggttgttcc tccttgagat aatataaata
     1621 taggatcagt aatgtgtcaa ctggttgctt aagcaattca tgctgcaaac gatccttgcg
     1681 ttttccttgt agcagataat caaaataaac agttttcgtg cgctcatttt gtattttttg
     1741 ctggtatttt cgataccttc gccattcttc agtacttaat tgaccaattt gtgccaataa
     1801 atcatccggc atacttttta tatcttgttg gcagatcatt tgaatcatca tgtctacttg
     1861 atagatttca ttgggcagta aaaaatgttt ttttgctaaa agttctagca tcgccaatcc
     1921 gcatgtctct ggtacgaccc tgttcttata taaattacgc agtttttgcc aaaattttat
     1981 gcttttgaaa aaagataatt ctaactgaat ttcttttgtt aagtaagaca aaaatcctcg
     2041 ccagtatgtt cttgcaggtt taacagaatg aaatgtatac cagttcccat agtaatagcc
     2101 taatcgtttt ttcatttcca gatagcctaa ttgtaaattt aattggttcc tttggctatc
     2161 aaaaagcaga aagctgccta gtgtccacaa tgtttgacat ttccaatgga taaaaatgtc
     2221 tggcatacga atttttttcg ctgggcctgg cccttgcaca tctacgacaa atgcctctgt
     2281 tgctcctttg ttaatcgcaa tatcaatagg tattttgttg cgatacccac cgtctgcata
     2341 tttatttttt ccgatctttc gataagccat agcgggataa aatgaagcag aggcgagtat
     2401 ccaatctggt atttcttctg tttttgtctg ttggatatca gtcactactt ccgctagttc
     2461 tggcagttta gtagacaccg tatataaacg tattttggga ttatgtttga gtaaggacaa
     2521 atccaaattg tctttgacca tcttttccaa tggagcagaa gaaaccccgc cttcaattag
     2581 tgctgttttc gtcatttggc gtctttctcg atagaagcgt tcacgaaggt cttcaactgc
     2641 agccatttct ggtaacgcaa gcacttgtct tgtcgacagc tttttccata aattcacagc
     2701 ttttttcata tctccttgta aaatcaatgc gccgttcaac gcacctaccg aggtacctgt
     2761 gataatctca aagttgatat catgttcctt cagcgcctgc cacacaccaa tctgataagc
     2821 accgtgcgct cctcctccac ctaaaacaag tgctgtatga tagaccagct ttttatttaa
     2881 ttgtgtggtt ccttgatagc cgtttttatg aaaaatacgc aaccattctt ctgatagagg
     2941 agattgaaat aaaaaacaac agttttcttt aataaaaaaa cgagcgcaag cttccatata
     3001 ccgaaaaaat tttttccatt caaaagtttc accttcaatc aacagattat taaaaataac
     3061 atctcctcta cttttagcaa tagtaaaata gacggtatat tttttcgata ctgctttaaa
     3121 agcacattgc ttttttgcag aacgccaaaa agcgtctcta ctttcttgat gactttgaaa
     3181 aaatggaagg ggttgttttg cttgctggat aggcgaatac agcgacattt tctgtgaaaa
     3241 gtaaactttt tttatctcca tcgcgctctc ctttttcttc aagtatacca gtacgtcata
     3301 aaaaggtcat gagtctcgta ttcgactttg tagattccat aagaaaacaa ttcataaaac
     3361 ctcctttaaa taaaaaaata caaaaatcac aaaaattaat tgaaaatgag agtgttttca
     3421 atgaaaacgt gattttgtaa tggaatttta aaataaaaga aacaagcttt tttaatgcaa
     3481 atgttgtaaa ataaaagaga ttaagaggaa ataagaggag gaacatgatg actgagtcag
     3541 tttatgtaca tattgatacc acaagtaatg ctgttttaac aaaagggctg actgctactg
     3601 actttgcaaa cagtatcgtg cattttcctc aaaacttgct cttgcttgat ccatctgctt
     3661 ctgctggaga atatgaatcc catacagggc tgaaagtaat ccgtggtaca gaaaatattc
     3721 agcgtttctt ttcctcttct cgtaacaggc gtggattcga tgaattgaag tggatcgact
     3781 ttactgattt aacgatgctg aaagaattga cacctttaga aatttcagaa ttattatatt
     3841 ttggtcatat gaaaacacat cttcattcgc cgttttttta taaactacag aataattttg
     3901 tatacttcga tcttaatgat cagctgaatc ggatttatta tcgctattta gatgaatttt
     3961 ataggatttt tgctagtaaa ttaagttcga tcttgtcaga taagatcaat gtaaaaaaat
     4021 cttttttcaa aaaagaaaca cctgttgaaa aaatcagtgt ggaattattg aaagaaatgc
     4081 gtaatttgat gcaggaaggg atcatttttt cttttgatca agttggtttg atcgatggta
     4141 aatatcgtat cccaatctat gtgattgaag attatatttg gaaattaaaa ggcacccggt
     4201 atcgagaaga ggaaatcatc gctactttaa tctactctgt caccgatcga cactggcaat
     4261 tggtagaaga tgccgatctt tcttatctgc cattgaagta gatctatttc ttatcaaaaa
     4321 ataaaaagga aacaagaaac taggacatga ttctgtctca agtttcttgc ttctttttta
     4381 tttacagctc ctgtcgttta tctggcacaa aaatcgaagg agtcgtttgt tggatcccta
     4441 ataaaacgat gatcgttaca atagctgtac tcaacccgct ggcaccattc attacgaaag
     4501 aaaagagcca aggattcatc ccccatagtg catacgctcc ccagaaaacc actcctgcaa
     4561 taaaatgcca aaaatatctg gaaagtgcgc caatcaatgc accaaacacg atgctttttc
     4621 taatttgttt cgtattatcg tctacatagc ctttttggac atttgaagcc atgagccctg
     4681 ctgcgcctgc aaaagtatag gcaatcgggt actcaatcaa cacttgaacg acacttaaat
     4741 aataaacttg tcccaacgga aaatgtagga tgccccaaat gaaacctgcc agcatccctg
     4801 cctttgtccc tcttcttaac gcaaaaagag tcaatggaat ctgccctaat gaaatagaaa
     4861 aactgctgcc gatctggatc ggaatcaacg acaacaccat cgctaacgct gcaacaatcg
     4921 ttccttctac ccaaactcta ttttttccca taaaaaaact tcctcctttg aataaaaaag
     4981 tcacaaagga ggaagcagct ttcgaaaata gtcaaacagc tgtttattca caattcctac
     5041 gctcgcataa ccgatacagg tacgaagggt ttagaaatag attcaatctc agcccaattg
     5101 gactcccctt tgtgagttta tttattattt attttttgtt tcaaacaatg gactaactgg
     5161 tttgttttca tggatacgtt tgattgcatc tcccattagt ccgccaacac ttacttcatc
     5221 gattttgtcg attttacgat cttctggaag atagatcgag tctgtaacaa ctagacgctc
     5281 gatagctgaa tcttctattc tttgtaaagc agggccggat aatactggat gtgtacatga
     5341 agcatacaca ctagttgcac cagcttcttt caaagcattg gcagccaatg tgatcgtacc
     5401 tgctgtatcg atcatatcat cgatcagtac acaagttttg cctttgactt gtccaatgat
     5461 attcattact tctgcaacat ttgcttttgg acggcgtttg tctatgatcg caatcggaga
     5521 tttcaaaaat tccgctaatt tacgtgcccg tgtgacacca ccatggtctg gtgaaacaac
     5581 gacaacatca tcgcctttga ttcctttttc taagaaataa ttggcaataa gtggcgcacc
     5641 catcaaatga tcgactggaa tatcaaagaa accttggatt tgaactgcat gaaggtccaa
     5701 agtcagcatt cttgttgcac cagctttttg aatcatgttt gctactaatt tcgctgtgat
     5761 tggttcccgt gcacgtgctt tacggtcttg acgcgcatag ccataataag gcatgactac
     5821 gttgattgtt tttgcacttg ctcgtttcag tgcgtcaatc atgatcagca actccatcaa
     5881 gttatcattg actgggctgc tcgttgattg aataacatag acatgcgatc cacgaatact
     5941 ttcttcaatg tttacttgaa tttctccatc actaaattga gtaacagatg attttcctaa
     6001 ctcgacgccg actgctgctg caattttctc tgctaatggg cgattggaat ttaacgcaaa
     6061 aatttttaat cttgggtcaa agtaatgttt tgacatgggg acctccactt tctttttcac
     6121 aactctagaa ttctacctaa taaatagtag tcatattttt taaataaatc aagtgatttt
     6181 gcaaaagtct tagtttagat aagggagttt ttttgcatat ccttctttat tgacttgtct
     6241 tgctctcgca attgccagcg catattctgg aatattgtct gtaattgttg acccggcagc
     6301 aatcgaactg tttttagcta cctcgacagg tccgatgata ttcgtgctag aaccaataaa
     6361 gctgtggtcg ccgacagtcg tatgatgttt gttctttcca tcatagttga cgaagacaac
     6421 accacatccg acattgattt cttctcccag cgtagcatca ccaacataag tcaagtgacc
     6481 gactttagtt cctttgccga tttgagcatt tttcacttcc acaaagtttc cgatatggac
     6541 gttttcgcca atttcagctt ttggtcgtaa atgtgcataa ggtcccacat ctgcatgttt
     6601 cttgacatgg ctgctttcaa tgactgagtt ttcaatgacg acgtgatcct caatcctact
     6661 gtctacgatt tttgaatgtg acccgatgac acaatcagaa ccaatgactg tatttccttg
     6721 gatttgtaca cctgcttcga tcaatgtgtc tggaccgatt tctacgcctg catcgatgta
     6781 tgtcgttgct gaatcgacaa agcttacgcc attgaccata tgcatctggt taattcgctt
     6841 tctcatgatc tcatttgctt tagctaacgc gatccgatca ttgactccca ttgattcttc
     6901 aaaatcatcc gtttgataag cagcaactgt atggccttct tcttttaaga tttcgatgat
     6961 atctgttaga tagtattcac cttgagcatt gtttgttcca actttgctta acgcatcgaa
     7021 caaagcttcg ttgtcaaaac agtaagttcc tgtattgatt tcttgtacaa gagcttcttc
     7081 tggtgttgca tctttttgtt ccacgatttt ttctacgatc ccaatatggt cacggatgat
     7141 tcgtccatat cctgttgggt tttctgcttg tgccgtcaag atcgttgcac ttgcattttt
     7201 tccttggtga tattcaaaaa gattgttcag cgtttcagta gtcaataatg gtgtatcgcc
     7261 actgataact aacgttgttc ctttttttcc ttccaagaaa gaagcagctt gcaaaacagc
     7321 atgtcctgtt cccaattgtt ctgcttgtaa cgcatattta ctgcgttctc ctagttgtgc
     7381 tttaacttgt tctgctccgt gtccaacgat cgtaatcact tcatctggtt tcgtttcact
     7441 gacccgatta atgatatgtt ctaccatagg tttaccagaa acgggatgta aaactttata
     7501 taattttgac ttcatgcggg tacctttccc tgccgccaaa ataattgcat aacgtgcgtc
     7561 caactgcgtc actcctaaat atagtttgct gatttcagtt tatcccagta tacccatttt
     7621 ttcaacaaaa caagtgattt tcttttatcc cagcgttttc tggataaaaa aatagataga
     7681 ccataacggg cctatctatt tggtaaccgg tgctctcctg ccaactcctc ggtcacaagt
     7741 cacactactc ataaaacatg aaaagctgtt ttttgaaatc gtttcttgtg acttagagtt
     7801 aaacggtagg cttacaacct cttcattaaa cgtttttcaa tcagctgacc ttcggtatta
     7861 gctcaataaa cggcaaaata tgaggagcaa tttttccgtt tattgagcta atactcagga
     7921 caggacgctg atttcacaac ctctagataa acggtgttca aaagccagtt tctcggtatt
     7981 aagccaaatt tatgaaaaaa tgtggaaagc cattttcaca aaatttttct tactactcga
     8041 aactaagcag ctttttcaca acctcttatt ctgaaaaata atttcctggc acaaccgtaa
     8101 tatttttcgt ttgagtatct acatctttga cataaagcag tgacgtataa tcatcgatgg
     8161 cgcgatgacc gttgaatttt gattcggcaa atacagtgat gccaacaagt tctgattcga
     8221 attcttcaat caagctcttc attccgttga ctgttccgcc gcctttcatg aaatcatcca
     8281 ctacaaggac acgtgaacca cgtttcaaac ttctcttaga cagttccatc ttttcaattc
     8341 tttcagaaga tccagacaca tagttgacac ttactgttga tccttctgtt atttttgagt
     8401 cccggcgtac aataacgaat ggcgcattca gataatagga cacagcttgg gcaataggta
     8461 cgccttttgt ggctacagtc attacagcat cgattttttc accaaggtat ttagaagcaa
     8521 tgattcttcc aacttgacgc agcagttcag gttctcctaa caaatcagag agataaacat
     8581 atcctcctgg aagcagacgg tcttgttctg atagacgttc tgctagagat tcaatatatt
     8641 ttttcgcctc ttcatatgaa atttcaggga tgaacaatac accacctgca gcacccggga
     8701 ttgtttccaa ggttccatac cctcgttctt taaatgtttt cttgatgatt cccaaatctt
     8761 cactgataga agatttagca gattcataac gttcggcaaa gcttgttaag gaaatcaatt
     8821 catgcgggtg attcaataaa tactgtgtca tgtcaactag acgttcactg cgacgtactt
     8881 tcacctattc caactccttt taagaaattt tatcgtttta cattatataa gtttttcttc
     8941 aaaaattcga gcattttatg aaaaaataag aaaatagttc ggtatttatt aaaataaaaa
     9001 gaagcctata aaaaattttt cgtttttata aggcttcttt tctttataat ttagttattt
     9061 tttcttctga aggcaaccaa tattcgtttg atgatattta caatcaggaa caaagcaata
     9121 aagactaatg tgattgttgc tcctggaggt gtatctagat aaaacgagct agttagtcct
     9181 gacagcatcc ctagaaatcc tacacaaaca ctgatagcaa tcacgacatt gaagcttttg
     9241 cctaatcgca taccgattgc tgcgggaaga accatgattg cggatatcaa aagtgcaccg
     9301 gcaatcggga tcatcacagc aatagccaca ccagtaatca cattgaacat catcgacatc
     9361 aaatgaacgg gtagcccatc cacgtgggcg gtatcttcat caaaagtcag aacatacatc
     9421 ggccgtttga ataaaaagaa caatataccg atggcaacga ataagattcc taaaaagatg
     9481 acttgctccc atgtaatggt cacgatcgaa ccaaacagat aggattggat acttgttgct
     9541 gaattccctc cgctcaaatt catcaatact aacgctagcg ccaaaccacc agccattaaa
     9601 atggcaatgg agatttctga ataggttcgg tagatcgttc gcagatactc caatatcaca
     9661 gctgctaata caacgactag catggtcgta agtgtaggat taaggttcaa aaagaatcct
     9721 aacgctaccc ctgctaaaga gacatgagaa agcgtatcag ccatcagcga ttgtcttctg
     9781 atcactaaaa acacacctag catcggggcg attccggcaa tgaagatagc ggcaagaaac
     9841 gctcttctca tgaattcata tgaaagcaac gccattgaga atcctccttt ctcaccagtc
     9901 ggatctgtct gtccgcatac tgtttgatat cttcatgatc atgggtgatc attagaactg
     9961 atttcccatg gacatgcgca ctatgtcgga gaagacgata aaattcattt ctggattctt
    10021 catccatacc tgttgttggt tcatcaagaa caaataagtc agggtcagta gcaaaaatac
    10081 gcgctaaact gattcgctgc ttttgtccgc cagacaattc acctattcgc cgatttcgca
    10141 tatcccacat ccctacagct tctaaagcac gctgtacatg ttgatgatct ttttcagaga
    10201 gacgcttgaa ccagcggcct cttggatatc ttcctgaacg gactaattcg atcaccgtac
    10261 taggaaaacc tgcattgaaa gatgcaactt gttgaggaat ataaccgata cttaattttt
    10321 ttccttcttg atttttctca gcaatcttta tcattccttt tgaaggtttc agtaatccta
    10381 acgatgcttt caccaaggtt gacttggctg ctccattttc tccagttaaa atgacaaatt
    10441 cacccgcatc tacatgataa gagacatctt ctagtacagg ttcatcatca tagtaaaagg
    10501 tcaaatcaga tatttcgata taacgcacct tacaacctcc attctaaaac ttaattgata
    10561 ctttctttta aagctttcag atttttttcc atgacagaaa tataattttc gcctgctttg
    10621 atttgttcat tagtcaagct ttctaaagga ttcaacactt ctagcttcac tcctgtttca
    10681 ttcgacaatg tctcagctac cttcgaagag gcattttctt caaaataaat cactttgatg
    10741 ttgtttttct tcacaaattc ttttagctca gctaagcgac ttggtgtggg ttcctgatct
    10801 ggtgaaacgc ccgaaatcgc tacttgtttt aagtcgtatt gattcgctaa ataagcaaaa
    10861 gcagcatgct gagtgacaaa tgtgcggttt gttgcatctt ttagctcatc ggagtatttt
    10921 tgatccagtg cttcaagctt tttgatataa gcatcggcat tcttcgtaaa agtttccttt
    10981 ttatctggat atttttcgcc taattcttca gcaatcgttc tgacttcttt tatagctaat
    11041 accggatcga gccaaacatg tggatcgtat tcatgtgaat gaccatgccc ttcttctgat
    11101 tcttcatgtt cgtctgcttc ttgcgattct aaacggtcga ttcctttagc tgcttcgatc
    11161 atcaaggtct gtttgctatc cactgaatcc tttaacgaat ccacaaaaaa ttccatgtct
    11221 gaactattat acacgaaaac atctgcatcg gaaatttctg ctctttcttt tgcacttggt
    11281 tcgaaatcat gcggctccgt tccagcaggg atcaaaagtt tcacgtttcc ttcatcccct
    11341 acgatctctt ttgtaaaatc atacatcgga taaaaagtcg taacgatcgt caaatcctct
    11401 tttttgtctg cttccttgtt cgtatttcca catgctgcaa acagtaaagc acctatcatt
    11461 accgtagctg tcaaaagata ttttttcatt tatatgctcc tttcaatgaa caaatcggaa
    11521 ttttacgatt tattaacgtg aactaatgta tcaaaataaa aaaacacagt caatagaaat
    11581 ccatcaattt ctgatttaag catgtatatt cttgattaaa tcgtaaaatg gatgagttgc
    11641 tgctcatatc tagccatttc actacaataa aaaactgaag aataccattt taggattcct
    11701 cagtttttca tcacctattt tacttcttat attttattgc agggttcgta ctaaataaac
    11761 ttcctcacaa aaacctttta acccattata tactctctgc gctcttgaat aatgttgaca
    11821 caaggcaaaa acggttggtc cgcttccact catcaatgca gcatctgctc cgtacttgat
    11881 catacgctct ttgatttgat ggatgactgg atgccgcttt cccgttatat cttctaaact
    11941 gtttcccatt tttttgatca tctgctgata atcttgctct cggatggctt cagcaagtcc
    12001 gtggatgtct tgatgttgga tggcttgcgt atctacttct ctaaacactg tacgtgtaga
    12061 gacactcatt cttggtttga ccaacacaac ccagcactgt ggcatagaag gtaatacttg
    12121 gatttcttcc cctttgccac cgacaaatgc cgtacttccg tagacacagt aaggaacatc
    12181 tgtaccgact tccaaaccga tttctgccag ttcttctaac gaacagccca gattccataa
    12241 ttggttgatc cctcttagag cagctgcaca gtctgtactt cctccgccta atccagctgc
    12301 tactggaata ttcttcttaa caaagatctt gacaccggtt ttgatattgt atttattttt
    12361 tagcaataaa gcagcttgat aaacattgtt ccgttcatct accggtaaaa atgctttatt
    12421 tgtttctaca atgattttgt cttctgttat ttcttcaaaa aatagatgat ctgccaagtc
    12481 tacgctcgac atcaccattt ccaactcatg atacccatct tgccgtctat ataatacatc
    12541 cagtcctaaa tttatcttgg ctggcgcttt ttcaatcaat tccatcctct cacccattcg
    12601 aaaagtctaa gtcgcaagta ttctatcata gggaaaaata aaagtatagc ttatgtctgc
    12661 ctagtggttg attttgtcat cgtttcaaca gctttcacag aattttctct tcataatcca
    12721 aacaagttct agtgattctt ataattctgt gagcacttct tctgccaaac tcggaacatt
    12781 tcctttttct tttcctatca gactgagtag ctgcatggta gcaaatccga aattacttcc
    12841 tttcctataa gcaaaataac gtccttccca atgatcgaca tattttaatt tcttttcata
    12901 agcagactgg aaggaataga aaaaattacc ataattatat acgatatgca tgactttttc
    12961 ttgaaagaaa gaaaaatctg tttctccaac attagctaat ggagctaagc ctagattggc
    13021 ttccgagtag cccattttct cgtatacaat aaacagattg gctaacagat agtcagctaa
    13081 ttcctcagat tctttaggta agacccgcaa caaatcatat cccgcctgct tcttcgtcat
    13141 cggctgagcg gtgatgaagc caacgacttt ttgatcttta cggacaatac cgacaccgct
    13201 agataataca tatgatttat caaatcgtcc cacagagaag tatttttctc gtgcaccttg
    13261 aagccatttt tgtgaaactt catttacagc ttgatgtaat tcttccggca gttgatcgta
    13321 ccaagtaaaa tggtatcctt ctttcatcaa acgttgatat tcaagttgct gactcagccg
    13381 agacaagtct tctgttgcta gatcaacaat ccctgcttca cctactttcg tgaagtgaaa
    13441 acccaattca tgaagcatca ctacgtagct ttctgatatc ttataaaacg caagctgata
    13501 gcctaaacaa tctgcttgtt tcataaactg attcgttgct gcccgcatca ttttaggatt
    13561 gccaactgga tctcctaaaa caaagcattt gtttcctttg atctgataac caaaaacgac
    13621 ttgatcttgg tcgtcttctt ggtaataaaa ataactgtaa cctgacaagc gaagctgatg
    13681 gcttgtagct gtgcctccgt atgtttccaa taaacggtca aaacggtctt tttcgtactc
    13741 actgccaagc ttcgtagtat cttcagctaa atattgataa agcgccacta aagctagcaa
    13801 tgagatgccc aaaccaataa gccctgagaa ccacacatca tctgaaggaa acaaaataaa
    13861 atgatttcct gttattcgac cgactaaaaa gcgtccgctg tgatagcctg caattgcgta
    13921 aacgataaac aaaaagccga acaagctagc atcaaagatt atagctcccc aagaataaac
    13981 gaattttgtt cgataaaatt cttttctgga taaccacaca gctaacagaa tcaagacata
    14041 taccaatatc aactgccaag ataacgtacg tgtgattgta tttaaaatac caaaagatag
    14101 taaagcaatc gtaggcagaa atgccttttt gacttttact gaaagtgctc tagcaaggcc
    14161 gagtaataaa aagccaacca atagattcac tgtctgatct aaaaaattga atgagaacgg
    14221 caataatact tgaaatagcc gactgattgc agacagatta gtgattgttg atagaagtac
    14281 catcatgatc cccgcaaaat agacagcact tacgagcacg atatgcgcaa ccttttggaa
    14341 aaacagtcgc ggaatgttat ctaaaaatcg attgattttg actcctgtat gtgtgatgaa
    14401 caatagaagt cccgtcataa aaggtagaac ataataaaac aaccgataat ataatagcca
    14461 aactactgct acatcttgcc gaacaggcaa ttgactcatt cctaagatca tcaaaacgtc
    14521 aaaagtcccc attccacctg ggaccatcgt cagcattcct atcaatgtag caatcatgaa
    14581 cataggatag atcgaaagca tcgaaatatc tattctcatc aacttgccga tgatcaaaaa
    14641 taccgcaagg gctcccgtcc attgtccaaa ggatgccagt agcagaccaa gcaagccttt
    14701 tggataaaac tcgaagaaca atgtctttct ctttagataa gcaaaaaaga aaatgactgg
    14761 tgctaaaaaa ctaccgccga aaagccagat ccaatagctt cgaaaaatac tttctgactg
    14821 aataaaaaag acatcaataa atgtaagaaa cgaccataca gacaaaccag tcagcataaa
    14881 tagtgcgact tttgatacag tggctaaaac catttttcta tttgtctgct ttccataaaa
    14941 actagcccgc agacttgctc ctaccacacc accaaaaccg gcgagattgt tgatcgtgtt
    15001 tgttacccac gcagcaagaa gaaactcttt tctttccatt tttggttttc cttgtttttc
    15061 taagactctg atcgtcaccc aatcatacaa caacatcgga gtgacaccca gcagtccagc
    15121 cagaatcatg agcaggatcg tcatgcggct ttgttgtccc atcctttgcc aaatatcttg
    15181 ccaactcatg ccattagcaa tatttgcgac ttgatttgcc acaaagacta acacggagcc
    15241 gaaaaaaatc agttttaaaa tcagactatg ttcctttatc cattgcagca tcaagtatcg
    15301 tttatttttc acattttccc attcctaact tgtatacttt tgtgtcatac cccaatgtta
    15361 tcttatttat tttaattttt ccactttaga cctgttcttt gcttgcgatg atagaaaaag
    15421 aaagatatcc taatgctaaa ggagaggata acatgaaagt aggatttatc ggcacaggga
    15481 atatggcaca agctattatt gatggtttat taaaaaaagg aacagtctcg aaagaagagg
    15541 tgttcgtttc cagtggacat tttgaaaatg cacaaaaatt tgctgctgaa actggcgtcc
    15601 atgcatgcaa aagtaatcag gaagttgcat cacaatcaga tatcgttctt ttagccgtga
    15661 aaccaaaaat cattgaaaaa gtattggaag aactaagaga atatagccag aaagtcttat
    15721 tcatttctat tgcttcagga aaatcattaa cagatttaga aacagcgctt gaagatcctc
    15781 aggcctccat cgtacgtgtg atgccgaatg tcaatgtcag cgtaggagca ggcgtttctg
    15841 cgatttgcaa aaatgaagct gccacggagg aacagcttca gcaagctacg atgatttttg
    15901 aagcaatcgg cagcgtctat cctttagcag aatcagattt cagtacattc attggccttg
    15961 ctggcagctc acccgcattc gtttacatgc tgatcgatgc gatgggacgg actggtgtac
    16021 tgaatggttt gtccaaacag acagccactg agattgctgc aaaagcaatt atgggttctt
    16081 gtcaaaaatt cctttcaagt gataaaaatc catgggaact tgtagaccaa gtttcttctc
    16141 ctggcggtac aactgttgca ggtgtagttg ccttagaaga agcaggattc atcccagcaa
    16201 tcatcaaagg aatcaatacg acgatcgaga aagatcttga gatgttgaat aaaaaataat
    16261 gatagcaatg ttttttcgtg ccttacaaaa aaagaagagc tgtggctttt gccgcggctc
    16321 ttcttttgta ttttttatta tttagcataa tcagttgcac gagtttcccg aataacgatt
    16381 actttgatgt gtccaggata atccagttct tcttcgattc gtttacgaat atcacgtact
    16441 aaacgaacag cgtctaaatc cgagatttct tctggcttga ccattacccg aacttcgcgt
    16501 ccagcttgaa ctgcgtaact tgattctaca ccggcgaagc tgttcgaaat attttccaga
    16561 cttcttaaac gacggatgta gttttctaat gattcacttc gcgcaccagg tcttgctgct
    16621 gagagcgcat ctgctgcagc tacaaggaca gagataacag aagtagcttc cacatctcca
    16681 tgatgagaag cgatcgcgtt gattactact gggttttctt tgtacttggc agctaattcc
    16741 gcaccgatct caacgtgaga tccttcaatc tcatggtcaa gtgctttccc aatatcatgg
    16801 agcaacccgg cacgttttgc taattggata tcttcgccaa gctctgctgc taagatacca
    16861 gctaattttg caacctcgac cgaatgcttc aagacgtttt gtccataact agttctgaat
    16921 cgcagacgtc cgatgatctt gattagatct ggatgaagtg tatgagcacc gacttcaaac
    16981 gctgcctctt ccccgtattc gcgaatacgt tcatccattt ctttacgaga tttctcgacc
    17041 atttcttcga tacgcgctgg atggattcgt ccatcttgta tcagtttttc caaggtcatc
    17101 cgtgcgattt ctcttcggat tggatcgaat ccggaaagaa caactgcttc cggtgtatca
    17161 tcgatgatta aatcgatacc agtcagcgtc tcaagcgttc gaatattacg accttctcgt
    17221 ccaatgatac gacctttcat ttcatcattc ggaagggtaa cgactgaaac agtcgtttct
    17281 gaaacttgat ctgctgcgca gcgttgaatc gctaatgata ataagttttt cgctttgcga
    17341 tctgcttctt ctttggcacg ctgttcagat tcttttacca ttagagttaa ctcatgattc
    17401 agctcttctt cagtcgattt catgatgaca tctcgtgcgt cctcttttga taaaccagca
    17461 attttttcta gttctttttg ttgatcttca atcatttttt caacgtcttt ttctcgctct
    17521 tcaattaatt gctgttttga actaagtgct tcttctttac tttcaagtga gttctcgcgt
    17581 ttttctaacg agtcatcttt acgattcagc gtttgttcgc gttgaatcaa acgattctct
    17641 tgagatttta attctaactt actttctctc agctcacttt caacttcaga acggtatttc
    17701 tgattttctt ccttagcttc taacaatgct tcttttttta gagtttctgc ttcttttttt
    17761 gcactatcga tgattccagc agctgatgat tgtgcaccag ctatttcttt ctcgtgacgt
    17821 gactttgcga ccataaaccc taaaccaaga ccgacaatta aaccgatgat agcgaggaga
    17881 atgttgaata ccataaaatc cacctccata ctatcttttt catttttatc atctatacag
    17941 cttctatgat aaattattct aaactcgtca atatgcatct tcgcatatat gtgtacaaaa
    18001 aacatgcaca actttattct aatgtttgta ccccgtagtg tcaactttaa ataaacaaag
    18061 aaacggcttt ctacttattc attaaacgat ggtttttaaa ataaatgaca ctagtttcat
    18121 ataggtaaac ctttaaattg agaaactttt ctattaaatt attctttgta gatgaacaga
    18181 tatttttatt ttatgtaccc actcgtataa ttaaataact cacgatttct ttattcaata
    18241 aaaaaacggc aggtcaagga gagtacctac tcttcagacc agccgttttt gtttatcata
    18301 atttttattc ttctactaaa ggcaattctt cttgtccttt ttcatcttct gggacagcga
    18361 cttcttcacc aataccataa gctgctctaa ctagagcaga aacttctgcc atcatttcag
    18421 gatgattagc catatagatt ttagcgtttt cccgtccttg accaatccga tcttctttat
    18481 aagaatacca agcaccgctt ttatcaacaa tgtctttttc tactgccatg tctagaagtt
    18541 ctccttcttg tgagatccct aaaccataca tgacatctac ttcagcgatt ttgaaaggag
    18601 gtgctacttt gttttttacg actttgatct ttgtacggtt accaacaata tctgtacctt
    18661 gtttcaattg ttctgcacga cgtacttcca aacggatcgt tgcgtagaat ttcaatgcgc
    18721 gtcctccagg agtgatttct ggattcccaa acatcacgcc tactttttca cggatttggt
    18781 tgatgaaaat agcgattgtt tttgttttgt tgatcgaacc agagagttta cgcaatgctt
    18841 gagacatcaa acgtgcttgt aacccgacat gtgagtcacc catttcgccg tcgatttctg
    18901 ctcgtggaac taaagcagca actgaatcga ctactacgat atctacagcc ccacttgata
    18961 ctaaagcatc agcgatctct agaccttgtt ctcctgtgtc aggctgtgaa agaagtagtt
    19021 catcgatatt cacacctaat ttttgtgcat attgcggatc taacgcatgc tcagcatcaa
    19081 tgaaagcggc cgttccgcca tttttttgta cttctgcaat agcgtgtagt gcaactgttg
    19141 ttttacctga actttcaggt ccatatactt cgatgatacg tccacggggg taaccgccga
    19201 cacctaaagc gacatctaac gcaagagagc cacttggaat tgtagagatt tgttggtcga
    19261 ttttttcgcc caatttcata atagagcctt taccatagct cttttcaatt tttttcagtg
    19321 cagcatctaa ggctgcttta cgatcatctg ccaatacgat aatcctcctt atatttacaa
    19381 atcagagcaa catttcatta tccttatcat atctttttta gtgaaaaaaa gcaagaaaaa
    19441 accgaacaaa tattcgcatt tatcattttc ttaaaagctg ttttctcaaa agatcaaatc
    19501 cttgcataac cgcattatat ctgatagcag cacgatctct ggcaaagtga tatttttccg
    19561 aaaccacgcc gtctttagat gaaatagcga tccatactgt tcctgcagat tgaccttcta
    19621 acgtgtccgg tccagccact ccggtgaaag ctacactgta atctgttctt gctatctcac
    19681 gtgcttgaat ggccatctgc tccacacatt ctttgctgac tgttccatat tctgctaata
    19741 gctccggatc aatctccaga aaaccagctt ttgtttggag cgagtaggta acgaatccgc
    19801 ctggaaatac ttcagataca ccagcaatgt cgcctaatgc ggcttggaag gcgccggctg
    19861 tcaaactttc cgctgctgtt acagtctgct tgttttcttt cagtagttcc actacgactt
    19921 ttgctagcga attatcatcg ccgtatccat aaaaatattc ccctactcgt tcttggattt
    19981 tttcttctaa tgctaaaaga gcttgattcc ctgcctgaac atcatttgtt ttcactgtca
    20041 gtcgtaatgt cacttcattt ggtttggcat atggtgcgat cgttggattg atctgtgtct
    20101 caatcagatc ttttagctca gtgaccagtc gcgattcacc aatcccataa aagcgcaaaa
    20161 ctttagaaat tagtttttct tcagaaggaa aacgttcctc tagtaaagga cgtacttgtt
    20221 ccacaaacat tggtttcaac tcattaggcg gaccgggaag aaggatatac gcatgtgtat
    20281 ctgtttgata aaaagtccct aaagcaagcc ctgtacgatt tggtagagga accccgcctt
    20341 cgataatctg ggactgttgc agattgtttt tggtcatttt tcgatgggtt gtttcaaaat
    20401 atgccaataa ttttttgtat ccttccgtat tttgtatgag agacttaccg aggtgagccg
    20461 cagttgcttc ttttgtcagg tcatcttctg tcggtcctaa tccgccacat aagagtatga
    20521 gttcacttct tgtttcagct agagcaatca actcttctaa acgctgctga ttatctccta
    20581 caactgtttg ataataaact tcgataccta gatcagctag ctgttctgac aagaaagtgg
    20641 cattcgtatt cacgacttgt cctagtaaaa gttctgttcc gacagctatt atttctgctt
    20701 tcattacttc ccgctccctt atatagtata cgctgtattt ttatattttt ttatttaaaa
    20761 agagggcaag gagctgtgac aaaaatcttg tcacagctcc ttgttccaaa taaacagtgt
    20821 tctcctgcca aaacctcggt cataagtcac aatatacata aaacatgaaa agctgttttt
    20881 tgaaattatc ccttgtgact cagagttaga cggcaggctc acaacctctc cactaaacga
    20941 tacttacatt gatcctttga acacaccgct gtttttgatg aagtaatcca cacctgaata
    21001 gatagtaaag atcagacaag cataaagcat gatttgatct actggaatac cgatcaggct
    21061 gaatgggata ttattgataa acagcaagat aatagcaacc atttgtgtag ccgtcttgac
    21121 ttttcccggc caagctgcag ccatgacttc tccatgttcg acaagtagta aacgcaagcc
    21181 tgtgacggct aattcacgac agacaatgat cgctactacc caaccagggg cctttccttg
    21241 gtcaaccaac atgataaaag cagtcataac tagcatttta tctgccaacg ggtccgcaaa
    21301 cttgccaaaa ttagtgacaa ggcctcgcgc acgggcaatt tttccatcta accagtctgt
    21361 gatactagct aaagcaaaaa taactgcacc tactagctgt gtgacagcca gtgtggtgtc
    21421 tcctacgtta aattgtcccc aatctaaagg taaacctaca accaaaatga aaatcgggat
    21481 catacaaatt ctaagtacag ttaatttatt tggtaaattc acactatcga ctcctttctt
    21541 ccctattcta cgtgactatc agcgaagttt ccaccgatat tatttacttt tccaaatgaa
    21601 tttattcaaa ggagtatttt tattgaaatt gatctttttg aattaacgaa gaaggaccgc
    21661 gacacagatt tgtcacgatc cttctttttt atacctacaa gtaaacagat gcgtaaacta
    21721 atttatacga tcattctgcg tattgaagag taaggttcac attttttgga ctctgattgt
    21781 tttcccctgg attaactggt acggattctc cattcgcttt gatcgttgca ttgcttgctg
    21841 caccaatcgt gatggtcgca tttgttgctg tttccggtaa cacggtactc tgtgtttcat
    21901 ttgctgccag tgtcccttga taaacatagg cattgtctac tagcacacct aaccatacac
    21961 gattgacagc agtaaattca agggttacag gcttggtagc gtctgtgata tttactgcga
    22021 tggcactgcc agaatcttct cctgtagcta ttgccatttt cttttcttca cttgattttg
    22081 ttgttgattc tactgtagaa gactctttgg tctgcgtgct ttgctctgag gaagaggact
    22141 cctcgactga tccttctact ttaagcgaag aagctgtgtc tccgattatt ggatcagctt
    22201 gacgatcttg ccaagtcata tagcccacga caacgacaat cgccaaagca accaatccta
    22261 ataaaatgac aggaagactt gtccaaaagc gacttggatg cgattcttcc tgatgcattg
    22321 cttttctaga agtacttact gtttcaggct gcggacgttc agggaccgat cctgtcaatt
    22381 tgcttttccc atcaaaaaca tcgactaaat ggtctccatc ttctcctaca gcttcagcgt
    22441 attgccgaat aaatgcccgc acgtaaaatt taccaggcaa ttggtcaaaa tcatcattgt
    22501 cgattgcttc caaataacgt ttttgaattt ttgtaatctg ctgtaattca tctaaagata
    22561 tttttttatt caggcgtgct tgccgtaatt tttctccgat ggtttcaaaa gccactcgtt
    22621 catcttctcc agtctgtttg attctccgaa gcatctgctg ttgcaacgaa agacgttatg
    22681 tttgggtgct gtgacaaaag tcatgtcaca gctccttttt tccgaataaa cattgttctc
    22741 ctgccaactc ctcggtcaca agtcacaata tccaataaat ataagaagct gttttttgaa
    22801 cttgttcctt gtgactcgga gttaaacggc aggctcacga cctctttctt aaacggtgtt
    22861 caatcagctg ttcctcggta ttagctcaaa aaccggcaaa atataaggag atatttttcc
    22921 gtatgtttct ctaatactca ggtcaaaacg ctgatttcac aacctcttcc ttaaacggtg
    22981 ttcaaaagct tgcatctgcg gtaataagtc caaccaagtt aaaaacatta agaagctgtt
    23041 tttacttggc tgttcttatt acttgatgca gggcagcttt ttcacaacct cttggtacac
    23101 ggtgttccag aagtagcttc ttcggcaata agccgaaata tcacaaaaat ttgagaagca
    23161 attttcgtaa attccttctt atttcttgaa gctgaccact tctgtcacaa cctctttgat
    23221 tacttcgttt gattttattt taatataagt tgattaaaag agagcatgat ttgttttatt
    23281 ttctcactaa tttttccaac acaactaaga ataccataaa agctgatttt ggaggaggtt
    23341 cctactacaa gtctaaaacg aaatttaaga cttttcctca taaatactgg tttattttgg
    23401 tctcatgtaa aactcgctga aggcctcttc acttataaat gcttccccag ctgccagtac
    23461 gtctttcatt tggatcgaat cgatgatttc aggaagatca aataaagttc gatcgccaaa
    23521 taaactttgc gtaaattgat tggcaatata ttcgatcgaa tttaatgatt ggaaatattg
    23581 tccaagcatt ttcttcttca gcaaatcgag atttgtttct gacacttccg gatcatcagc
    23641 gaatccaaga atgatttctt tgactttttc tgctgctttc tctggttcgt ccgtatctcc
    23701 gctgaagtcc gcaaagtgaa attcacgatc caagctgaat tcaaaaccaa agctgtcatc
    23761 gataattcct tgattgtaca tcgctagata gtttcgagaa gtattgccta aaatcatttg
    23821 gaacaacaga ttgattgctg ttttatagcg taacagttct gttccttctt gcggcaatgt
    23881 gtctaatcct ttaataccaa gtacaaattt atctcgtgta atggctgctt ccaatgcact
    23941 ttgtttgatg atttcttttg tgttttcagg gaaataacgt acaatttctt gctttggagg
    24001 gaaatttttt gcttcttggt tttcccgaat aagtttcatc aatttctcag gctccatctt
    24061 accaactaca aataaaacca tattgcttgg ctgataaaac gtccgatagc acgtatacaa
    24121 gtcttgagct gtgattttgt cgatactttc aaccgtgccc gcaatatcga tatgcaatgg
    24181 gtgtgtagga tacaagttat ttagtatgcc aaaaaacatc cgccagttag ggtcgtcttc
    24241 atacatttgg atttcctgac cgatgattcc tttttccttg tttacagttt cttctgtgaa
    24301 gtaaggtgct tgtacaaaat cgatcagagt cgtcagattc ttttctacct gatccgtcgt
    24361 agaaaacaga tagctggttt tcgtaaaact tgtgaaagca ttggcggaag ctccttgttt
    24421 cccaaataat tgaaagacat caccatcttc tttttcaaac aacttatgtt ctaaaaaatg
    24481 ggcaattcca tctggaactt tcaccttttc tttttcacca tagggaataa attcgttatc
    24541 gatcgaacca taattcgtac tgaacaaacc atatgtcttg tgatagtcat ttttaggcaa
    24601 caaatacacg gtcaaaccgt ttggcagtac ttcatgataa agtgtttcat tgatttgctc
    24661 atattctgtt ttattcattt gcatttcctc ctgctaaaaa gaagattgcc tgcaattcga
    24721 tttgctcagc tacttgttgt atctctttga tcgttacgct ctccatacgt ttcaaccatt
    24781 cttcatcaga taattttgtt tccggcagcc agctgtccaa aaaagaagct tcgattgccg
    24841 cttgcggaga gtctagagaa agcagatatt ggtttctcag cattgctttt gtctgagaca
    24901 gttccaactc tgttatttca ccatttcgca aactttctaa ttgctcgtga atcagatgaa
    24961 gtacttgatt tcggttcttt tcatcgatac cggtttggac actcatgaat cctcggaacg
    25021 tatccacgct actagaggca taataagcta gactttcttt ctctctgaca ttcatgaaaa
    25081 gtttagagtg aggaaaaccg ccaaataaac cgttaaagac cattagcgca aaacgttctg
    25141 gttcatcgta atacacattt gtctgataag ctaggttcag ctttgcttga acgattggct
    25201 cacgtacttg tcgttccttc acgatattca cttgaggttg ggtataaaac agatctggat
    25261 aaactgtttc ccgcgactca aatggtaatt gcccaactgc ttcagctgct ttgtccggat
    25321 caacatcgcc gacaacaaaa atgtcgattt gatcatttgc catcatttct tgatagtagg
    25381 acgctagcga actagcagtg atcttgtcca aatcttcgac tacgcccaac cctgggatct
    25441 tttgttccgg gctgttttca aaataaagtt cttgcaaggc ataggaagca aaagtttgtt
    25501 tatcttcctt caaactttcc aaatatagac gcagattgtt cttttccaag tcaaacgtca
    25561 actgatcaaa ctgatgattt ttaatatttg gataaaataa aacctctttt aaaaaatcta
    25621 ccgcttgaga aaaaaggttt ggatcattga catattcacc attcacaaaa ctgatccctg
    25681 cgtttagcca atgtaaattt cctttttttc taactgataa tccaaagctt gcgccataaa
    25741 gctctgcaag ttgcgcactt aactttgtct gatccggata attcaaacta tttgtttcca
    25801 acatgctgct gagaagtgaa cgtttcgtga tgacttcttg ttgcagacgc gcagtaaaac
    25861 ggataaaaat ccggatcgtt ttgtattgtt ttgttggtaa gacatgaaga ttcacgcctt
    25921 ctgccaattg atacaccata tttatatgct ccttttcaca gttgattgcc cgcttactct
    25981 tttaatgggt caacctgcct tttttactta ttcctctgct tgaaatttat aagttcaggc
    26041 aattcgccgt tttttctaaa tgatgttaca ctttatagta tagcatagat gttttttatc
    26101 aaaagaaaca gacggctaaa agcgtatatt gtttttttat tttttatttt tcgatatact
    26161 aaagacaaat aaaagaaggg agggtcattc atgatcaaag aattcaaaga gttcatcatg
    26221 cgtggagatg tcttggatct tgctgtcggc gttgttattg gtagtgcgtt tacaagcatc
    26281 gtaaaccaag tggtgcaagg cttgatcaca ccactaatag gttggtttgt cgcaatgatc
    26341 acaggtactt ctgatttaga aggagcactt tcaattcttg actggtcgcc gacaaaaggc
    26401 gtcacatttg cgtttggtaa cgttattagt gctatcatta catttctgat cactggtttt
    26461 gtcttattct tagttgtcaa agcggcaaac cgtgcgaaga atttacgctc caaagaagag
    26521 caagtggaag tggaagaaac tcctactgca gaagattatc ttagtgacat acgcgatctt
    26581 cttgccaaac aagtggcaga agacaataca catccagtag agcaaacaaa tctttccgat
    26641 acttctaaat aataaagaat ctaaaaaaaa gaaagccgat tttcagtgtc ggctttcttt
    26701 ttttagattc ttaacttgct acttgttcct ttttcatgtc gatatgtgga atatcatctt
    26761 ccaaatacac atctgagatt gccttgaatc caaacgactc ataaaaagct tgtaggtatt
    26821 cttgtgcgcc gatcacgatt ggtttttctg gaaaattttt ctggatcatg ttaatcgttt
    26881 cttgaacaat ctttcttcct aaaccatctt tacggttgtc ctgatgaaca aggacacgtc
    26941 caaaatggat actctccgct tcttcatata ctcgcgtgta ggcaaggatc ttcccatcag
    27001 tatcttgaaa aaacgtatgc caagcttgtc catcaatgtc atcaacttct tgataaggac
    27061 actgttgttc cacaacaaaa actgcgattc gttctttgac gatcgcgtaa aactctgctg
    27121 ttgacaattc ttcaaatttc tttacctgat attccactaa gcaaacgccc cctgcttttt
    27181 tattcttagc ataccgattc gcacacaaaa aagcaaacga accttacgaa tc
//
LOCUS       DAZKKZ010000040        26160 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.040, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000040 DAZKKZ010000000
VERSION     DAZKKZ010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 26160)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26160)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26160
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.040"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(62..1093)
                     /gene="queA"
                     /locus_tag="ACG8LA_001787"
     CDS             complement(62..1093)
                     /gene="queA"
                     /locus_tag="ACG8LA_001787"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HFQ0204084.1"
                     /translation="MLTTEDFDFDLPEELIAQTPLKDRDHSRLLVLDRKTGEMEDKHF
                     HEIIEELQPGDALVMNNTRVLPARLYGEKPDTGAHLEVLLLTNTQGDTWETLIKPAKR
                     AKVGTRISFGDGRLQAVVKEELEHGGRIIDFEYEGIFLEILESLGEMPLPPYIKERLE
                     DPDRYQTVYAKENGSAAAPTAGLHFTKELLDEIEAKGVELVYLTLHVGLGTFRPVSVD
                     KIEEHHMHSEFYRLTEEAAERLNQVRKNGGKIVAVGTTSIRTLETIGTKFNGEIKADS
                     GWTDIFITPGYEFKVVEAFSTNFHLPKSTLVMLVSAFAGRELTLSAYQHAIEERYRFF
                     SFGDAMFVK"
     gene            1286..2461
                     /locus_tag="ACG8LA_001788"
     CDS             1286..2461
                     /locus_tag="ACG8LA_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628506.1"
                     /note="Members of the family are the ATP-binding subunit
                     of ABC transporters for substrates such as betaine,
                     L-proline or other amino acids, choline, carnitine, etc.
                     The substrate specificity is best determined from the
                     substrate-binding subunit, rather than this subunit, as it
                     interacts with the permease subunit and not with substrate
                     directly; Derived by automated computational analysis
                     using gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015837 - amine transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="betaine/proline/choline family ABC transporter
                     ATP-binding protein"
                     /protein_id="HFQ0204085.1"
                     /translation="MIEFQNVSKIYKGGKVAVEDVNLSFEKGEFICFIGTSGSGKTTT
                     MRMINRMTDPTQGKILIDGKSIQEIDPVELRRQIGYVIQSIGLMPHMTIRENITLVQK
                     LLKVSQEERNKTAEKMIDLVELPREMLDRYPHELSGGQQQRIGVVRALAANQDIILMD
                     EPFGALDPITRDSLQDLVKDLQERLGKTIVFVTHDMDEAIKLASRIAIMSEGRVIQFD
                     TPENILRHPANDFVEELIGEDRLLQAKPNATRVGEVMLNTAITITPEKSLQEAIKLMR
                     EKRVDTLLVTDNSNVLKGFIDVETLNKKRGKVSSVGDILNKHVFYVKESAYLRDTLQR
                     ILKRGLKYVPVVDEQNKVVGILTRASLVDIVYDVIWGEDPATTDVAESATPEESKEV"
     gene            2465..3106
                     /locus_tag="ACG8LA_001789"
     CDS             2465..3106
                     /locus_tag="ACG8LA_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFQ0204086.1"
                     /translation="MQQFFHQHGSEILSKGFEHLYISGLALIIGIIIAVPLGVLLTRF
                     PKAATIVIGLTSALQTIPSLALLALMIPLFGVGKLPAIIALFIYSLLPILRNTYIGMK
                     NVDWNYRDVAKGMGMTEFQSIFSVELPIAMPTIMAGIRLAAVYVIAWATLASYIGAGG
                     LGDLIFSGLNNYQPDLILAGTIPVTILALLADWLLGLLEHRLTPIALREENEE"
     gene            3103..4020
                     /locus_tag="ACG8LA_001790"
     CDS             3103..4020
                     /locus_tag="ACG8LA_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmoprotectant ABC transporter substrate-binding
                     protein"
                     /protein_id="HFQ0204087.1"
                     /translation="MKRILKMTMVLFSLLILASCSFPGLASNTDEDTISITGGITSEA
                     QILASLVAGMVEHYTDKNTAIINNLATTTINHQAMMNGDASISAARYTGTDLTTTLNL
                     PPEKDPKKAFATVKDEFEKRYGQTWFPSYGFENTYVFLVRKDTAQKYHLSKVSDLKNV
                     ADELVAGVDTSWINRKGDGYDGFQETYGFSFNSILPMQIGLVYDAVEAGKMDIVLGYS
                     TDGRIASYDLVMLEDDRQFFPPYDAAPVVDNKILADTPHLKEALNKLGHTISTEKMQE
                     LNYEADNNLVEPSVVAQRFLQENHYFEGK"
     gene            4017..4688
                     /locus_tag="ACG8LA_001791"
     CDS             4017..4688
                     /locus_tag="ACG8LA_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFQ0204088.1"
                     /translation="MKQLDKMNVFQQFFYYFQENGSYIFAQFIRHFLISIYGVLFAAV
                     VGIPVGIMISRRRKLANWVIRLANIIQTIPSLAMISILIIGLGLGVNVVIVTVFLYSL
                     LPIIKNTYTGMIQVDKNILDVGKGMGMTARQRLFMVELPLSVSVIMAGIRNALVVAIG
                     ITAIGAFVGAGGLGDIIIRGTNATEGTSIILAGALPTALMAIITDWLLGILERRLDPA
                     SRTSR"
     gene            complement(5229..5717)
                     /locus_tag="ACG8LA_001792"
     CDS             complement(5229..5717)
                     /locus_tag="ACG8LA_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-glycoprotein
                     endo-beta-N-acetylglucosamidase"
                     /protein_id="HFQ0204089.1"
                     /translation="MTRKISKIGASLLVLAVATTIDYRQSEAKTIGNVVYRETAKSML
                     KKAMDNQPESSYWFPEDSLAWSFGKDTDTKYNTSVVPLAERVSKATLPNMNVTQTEEV
                     KVVALSAMNSSINGNASRGIDIFYANVFSYWQYIDQLVYGGALLVKDHRIAKSSCDGC
                     SP"
     gene            complement(5918..6184)
                     /locus_tag="ACG8LA_001793"
     CDS             complement(5918..6184)
                     /locus_tag="ACG8LA_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008219 - cell death [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HFQ0204090.1"
                     /translation="MSNYTVAIKNSAKVDLRKIKQTNLKKQFEEVIQTLKEDPYMPTQ
                     SFEKLRPTHEGRYSRRLNRQHRVVYKVDEENKVVEIYSAWTHYE"
     gene            complement(6184..6447)
                     /locus_tag="ACG8LA_001794"
     CDS             complement(6184..6447)
                     /locus_tag="ACG8LA_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0097351 - toxin sequestering activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0045927 - positive regulation of growth
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HFQ0204091.1"
                     /translation="MANTTMNPSTARKNFYQLLKEVNENHTEIEIISDRSGNNAVLIG
                     LEDWRAIQETLFLEQTGTLDKVRDREKDDSSFTNIDDIDWEAL"
     gene            6968..7108
                     /locus_tag="ACG8LA_001795"
                     /pseudo
     CDS             6968..7108
                     /locus_tag="ACG8LA_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736676.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
     gene            complement(7250..9073)
                     /locus_tag="ACG8LA_001796"
     CDS             complement(7250..9073)
                     /locus_tag="ACG8LA_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HFQ0204092.1"
                     /translation="MDYLKRLLVGKPLKSAENDEHKLTRFAALALLSSDALSSIAYGT
                     EQIVVVLVALSAAAIWYSLPIAAFVIILLISLTLSYRQIIHAYPHGGGAYVVSSENLG
                     KNAGLISGGSLLIDYMLTVAVSVSAGAEAITSAVPALYGHQVAISVTIVLLLMMLNLR
                     GLRESASFLLFPVYTFILVISLLIVVGLYNIVTGAVPLQATALPGAAVPGVSIALILR
                     AFSSGSSSLTGVEAISNAVPFFKKPRAKNAAATLTMMALILGFFFVGITFINYWYGIV
                     PEKEVTVLSQIGKAVFGHGILYYVLQFATALILAVAANTGFSAFPVLAYNLAKDKFMP
                     HMYQDRGDRLGYSNGIITLALGSIVLLFIFHGSTERLIPLYSIGVFIPFALSQTGMVV
                     KWKKEGKRWLSKSIANITGAFISYAIIAILFVYRLGDIWPFFIIMPIVMFIFYKIHDH
                     YKKVAEQLRLENDAKLHDYDGNTVLVLVGNVTRVNIGALNYARSIGDYVVAMHVSLDE
                     DVEKEKEIEAEFKKHFPDVRFSIVHSSYRSIENPIIRYVDIVSKNAAKQNYTTTVLIP
                     QFVPNRRWQNILHNQTSLRLRLRLSWRENIVVSTYSYHLKK"
     gene            complement(9671..12376)
                     /locus_tag="ACG8LA_001797"
     CDS             complement(9671..12376)
                     /locus_tag="ACG8LA_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip family protein"
                     /protein_id="HFQ0204093.1"
                     /translation="MQSIKNTLRLYLLDWKRIFKNPIATLLIIAIMIIPSLYAWFNIK
                     ALWDPYGNTGELPIAVYSADKPAEFQGKEVAIGEQVIESLHKNKQLGWQFVDSKEQLE
                     DGVRSGKYYAGIYLPKDFSEDLLSFTSGDIKKPKIEYTVNEKINAIAPKITDKGASSI
                     QSQITNEFIKTASSTLLKVFNEIGYDIDTNLVSINKVKDMILSTDENLDTIDGYTKQV
                     LELQSQLPEIKEKLNKANEFVDYIPKVDEMGEKVVALNDKMPELKDQAKIILDLQEKI
                     PEIQNAGKQLAEIDGDFASIQETMNQGIDEAKQGLTIIQQVQDILPDVKNLENQASDL
                     ANQTKSGASQLKDAIPSITNSVDVTLKSIGQVATTTGSLIDTVRTAIEDGKLTDDEKK
                     NISNVLNGFIDGISQQQNAIDKLVEFLTKLQTSAGNTKLQPIIDQLNQLKPLLSNLQN
                     RLSALNTAVQNEDTKAIDELLDQIDAVVNNINGIIAGINTGQISSTVTSLLDQVIDTI
                     GTAQGALSKADQIDFDSLLSSTKATVTNAVAILEKYQKEMPAIGQEIHDANTMLNGNM
                     DTIVNGINEGADLYNNELPIIQQKLGLAADFIQNDWPALKNEITGTLTTVNEKMPEVE
                     TAVNAAADLINNDWPNIKAGIQKAADAIRKGEQEVDLGEVIKLLKLDATKESDFFTQP
                     VELQTNALYPIANNGSASTPFYTALCLWVGAVLLSSVATTEYYLGKKDRNNFTKREQF
                     VARMLTFLTMAIAQSLIVTLGNIFLLGVDVQNPVYSVSFAVLIALAFMMIVYVLAALF
                     DNVGKGIAIIILVLSISGGGGNYPIQVSGKFFQMINPFLPFTHAVNLLRESAGGIYWP
                     NATKAIWIMIGLFVVFGIVGTAIYPFIEEKMTKFKEAAHESHIFH"
     gene            complement(12682..13629)
                     /locus_tag="ACG8LA_001798"
     CDS             complement(12682..13629)
                     /locus_tag="ACG8LA_001798"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="HFQ0204094.1"
                     /translation="MRRFAINGYGEAQDVFEEIDAHPREVGSGHVRVEIKAFSVNPYD
                     VALRLGEMKEIRTLKFPYVPGNDGAGIVTEIGSDVTTVHVGDRVAVHAVGGTYGEEVV
                     LPSAKVAKIPDKMSWEEAAGMVTPGITAYNLINHLTEIQPTDTVMILGASGAVGSSLI
                     QLLHEKGIRILTSASSKNEEKVKKLGASAFAAYDKTNPGLQFADQADLVIDATKGSIK
                     GETGIQIMKPGGRYVALNDLPDLDLRQKKEGFYESFVPRKEYLDAEAFAGIIKAYQKG
                     AFHVFISMNLSASLKHVIQAHQLVEGHPPAGKIILSFEK"
     gene            13819..14088
                     /gene="rpsN"
                     /locus_tag="ACG8LA_001799"
     CDS             13819..14088
                     /gene="rpsN"
                     /locus_tag="ACG8LA_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HFQ0204095.1"
                     /translation="MAKKSKIAKAKKQQETIERYAALRQELKAQKDYEGLHKLPLDAR
                     PERLKNRDLIDGRPRGYMRKFGMSRIKFRELAHKGLIPGVKKASW"
     gene            complement(14264..14626)
                     /locus_tag="ACG8LA_001800"
     CDS             complement(14264..14626)
                     /locus_tag="ACG8LA_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HFQ0204096.1"
                     /translation="MVKRGDIYFADLSPVVGSEQGGTRPVLVIQNNLGNHFSPTIIVA
                     AITAKMAKPKLPTHIGIKATGTGIERDSVILLEQIRTIDKSRLKEKVCHLDRPIMAEV
                     DRALKISVGIEALTPVTK"
     gene            complement(14637..15758)
                     /gene="alr"
                     /locus_tag="ACG8LA_001801"
     CDS             complement(14637..15758)
                     /gene="alr"
                     /locus_tag="ACG8LA_001801"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008784 - alanine racemase activity
                     [Evidence IEA];
                     GO_process: GO:0006522 - alanine metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HFQ0204097.1"
                     /translation="MVVAWHRPTKAVIHKKAITENVANEVARLPQGKELFAVVKANGY
                     GHGAIETAEAAVAGGASGFCVSNLDEGVELREAGFTQPILILNMVPYDALTVAVAHDL
                     SVTAGTREWLQAAAAVLEKSKLETPLSIHLKADTGMGRIGFCTPEEVKEAAAFIKESR
                     VLEWEGLFTHFSTADQADDTYWNLQKERFIEVLKKLPELPRYVHVSNSATALWHDETI
                     GNMIRYGVAMYGLNPSGHALPEVYPLQPALELVSELIQVKKLPAGEGIGYGETYITPE
                     AEWIGTIPIGYADGWPRKMQGFSLLVEGNYCETIGRVCMDQLMIRLPQEFPVGTKVTL
                     IGKNADKEITMQDIADQLGTIHYEVACGLGQRIPREYQE"
     gene            complement(15774..16124)
                     /gene="acpS"
                     /locus_tag="ACG8LA_001802"
     CDS             complement(15774..16124)
                     /gene="acpS"
                     /locus_tag="ACG8LA_001802"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008897 - holo-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HFQ0204098.1"
                     /translation="MIKGIGIDAVELPRITRLIEEKPKFIARILTSDEMKLFQSLPFH
                     RQVEFLGGRYACKEAFSKAWGTGIGKVTFQDVEILKNENGQPVVTRSPHEGNVWVSIT
                     HTNETAFAQIILED"
     gene            complement(16254..17765)
                     /locus_tag="ACG8LA_001803"
     CDS             complement(16254..17765)
                     /locus_tag="ACG8LA_001803"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HFQ0204099.1"
                     /translation="MKFKELELSPELLKSVERAGFEEATPIQAETIPLALAGKDVIGQ
                     AQTGTGKTAAFGLPMLEKIDPDRHELQGLVIAPTRELAIQTQEELYRLGRDKKVRVQA
                     VYGGADIGRQIRGLKDRPHIVVGTPGRMLDHINRHTLKLGTVQTLVLDEADEMLNMGF
                     LEDIEKIISQVPDQRQTLLFSATMPPAIKNIGVKFMKNPHHVKIKAKEMTADLIDQYY
                     VRAKEYEKFDIMTRLFDVQTPELTIVFGRTKRRVDELARGLEARGYRAEGIHGDLSQQ
                     KRMSVLRSFKSGHLDILVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KGGMSVTFVTPNEMDYLHVIENLTKKRMTTLRPPTEKEAFKGQLGAAVEQIETKLAEN
                     GLDKYLQTADKLLEEYSAQDLVALLLKTTAKDPADAVPVKITPERPLPMQKKGYNKNG
                     KRGGGNNRNRRDGGNYRGNKSKGGYSKNNNSQKDGGKRHNDKKRGFVIRSNND"
     gene            complement(18087..19439)
                     /gene="murF"
                     /locus_tag="ACG8LA_001804"
     CDS             complement(18087..19439)
                     /gene="murF"
                     /locus_tag="ACG8LA_001804"
                     /EC_number="6.3.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0047480 -
                     UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase
                     activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HFQ0204100.1"
                     /translation="MNLTIQEIAQAVGSECSALTKITNVEFDSRKITEGSLFVPLAGT
                     RDGHEFIQQAITNGASASFWSLPVEQAPKNFPVIPVADPLKAMQQLATYYLEKVGAEV
                     VAITGSNGKTTTKDLTASVLSEKYKTYKTQGNYNNNIGLPYTILHMPQDTEKIVLEMG
                     MDHANEITELSLMAQPKAAAITMIGEAHIENLGSREGIAKAKMEITDGLVSDGLLVVP
                     ADEPLLTPLTATLVQTVTTFGIGNGDVHAEVTAKGKAQTDFVVEGETFTIPLPGSYNV
                     TNALIAYTIGRFFGLSIPEIRQGLAHVSITQNRTEWLTAGNGAAILSDVYNANPTAMG
                     LVLDTFKNLPTKGRRIAVLADMLELGKESLNMHAQMSEHIDPEKFAMIFLYGEQMHAL
                     KEELNQKYPQLPVFYFEKEKNKLIDAIKQNLAATDSIMLKGSNSMGLFEVVEQLQQMK
                     "
     gene            complement(19592..20668)
                     /locus_tag="ACG8LA_001805"
     CDS             complement(19592..20668)
                     /locus_tag="ACG8LA_001805"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HFQ0204101.1"
                     /translation="MKITLLYGGRSAEHEVSILSAFSVLNAIYYNYYQVQLVFITKEG
                     QWVKGPLLTEKPASKDVLHLSWDPSGQTEEGFTGKVINPGEIKEEGAIVFPVLHGPNG
                     EDGTIQGFLETLNMPYVGAGVLTSACAMDKIMTKYILQAAGVPQVPYVPVLKNQWKEN
                     PKKVFDQCEGSLLYPMFVKPANMGSSVGITKAENREELQNALATAYQYDSRAIVEQGI
                     EAREIEVAVLGNEDVRTTLPGEVVKDVAFYDYEAKYINNKIEMQIPAEVPEEVYQKAQ
                     EYAKLAYTMLGGSGLSRCDFFLTNKNELFLNELNSMPGFTEFSMYPLLWENMGLKYGD
                     LIEELIQLGMNRYHQRQSFFEKNE"
     gene            20864..22609
                     /locus_tag="ACG8LA_001806"
     CDS             20864..22609
                     /locus_tag="ACG8LA_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AarF/UbiB family protein"
                     /protein_id="HFQ0204102.1"
                     /translation="MAQTNPRSRLAEIIRVFINYNVVPNFVQQKNPEQVKKAFEELGP
                     TFIKIGQMLSVREDLLSSAFTQTFKTLQDSVPSDTFSTVKKTIETELSLSLSDIFDDF
                     SKSPFASASMGQAHRAKLKNGDAVVVKIQHPNIAEEIRLDLQLFERAIPLIKYIPETS
                     VVDLKGVLQEVKRSLINEMDFLKESQNGEQFYQKNNGWKEIRSPKIYDAFCSKKVIVM
                     EEMSGKNLNHLMNAENKTETFITGIQNKQLKQEVAKLLVENFMKQVFDDGFFHADPHP
                     GNLLFHVLTKEEQTQASRKTETVHEKEFGSFAFRASTSAEDPVAPYTINYIDFGMMGH
                     LSAGLRQKLTQAVLALYTKDAYRIEKAVLRLCQQEGSFDESRFHQELTSFLEQYYDSP
                     IDEINLQEVFTHVVTICHQNNLQFDRDITLLLKAFGTLEGVIRVLDPEVSLMEVASPF
                     AQHYFLTHLDVEDTLKQSGLDLLEGMKAAPKIPQQLHHLLEMWTSGQGKVNLELKKQD
                     KLLSRIESMINRLVFGMILAALIVGSSLLVQAAPVENAEVVSLLGIFTYAIAAFVIIF
                     LAIDALIQMYKKRKK"
     gene            complement(22889..23326)
                     /locus_tag="ACG8LA_001807"
     CDS             complement(22889..23326)
                     /locus_tag="ACG8LA_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaiI/YqxD family protein"
                     /protein_id="HFQ0204103.1"
                     /translation="MRLFIDGDGSPVKEDVIKLGESYGLDVVIVTSVDHYTTKEYANH
                     VQIVYVDRGADSADYKIVGMVKKNDFLITQDYGLASLVLPKGVRVFHHSGKEFDEANI
                     GTLLEQRYHSGKLRKAGIRTKGPKPFTEKDHMSFRQALKKAID"
     gene            complement(23310..24683)
                     /locus_tag="ACG8LA_001808"
     CDS             complement(23310..24683)
                     /locus_tag="ACG8LA_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204104.1"
                     /translation="MFEKLKRFGRNFTQTTPFILSNTVIFIPYLLFLGLTDSHNWLTI
                     LPFTLFYAFRMTGLFLVNSLRFGLDSYTLLMIALLIGGAGSLLGILGVFYFPLFYFSS
                     VLLGLSAAWLVPANTTVNFHEKTQGFINMDGKKYLFAAIWLFLLYQAIELPAPTQIAA
                     SFTIYTLFYVMAYHTVSHYPRYELDFKDIKRNLVATRELVLFLIFFGLLFLLRNARLL
                     FDERLFDLAIYGFLLLFILFVFVLGHQKKEWKLPSWLNLFTFLNGMLGNFLFLFSSFY
                     VGILYGLEKLSIFMYLPYAAGLIAAKIVGPWILKRLTWSPLAMQLLGLSSSLLVLLIP
                     NGFAIGVFLLSFWHVVTGSWLNKEYYQTDTAIPMDRRIVVKYTTQNKGSVIHQFLLMT
                     LLFVLAKEMGEPIHLLLITLNHESVPIESVQLLILAKWINVGLLLSGLVTVYHLWKKA
                     KKNEAIH"
     gene            complement(25005..25493)
                     /locus_tag="ACG8LA_001809"
     CDS             complement(25005..25493)
                     /locus_tag="ACG8LA_001809"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFQ0204105.1"
                     /translation="MEKIKVTENELDELMAVIQEVWPEAFVPIIGQKQVDYMLKTYQS
                     KKQIQKELTEGVSYFLLKSEEKTVGYTAYEEINGKIYLSKLYLLNKVRGQGLTSSVFR
                     WYEELAAQTKEREIFLRVNQGNHQAIEVYKHEGFEITEELISDIGQGFQMVDYKMKKA
                     LA"
     gene            complement(25515..26117)
                     /locus_tag="ACG8LA_001810"
     CDS             complement(25515..26117)
                     /locus_tag="ACG8LA_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VTT domain-containing protein"
                     /protein_id="HFQ0204106.1"
                     /translation="MSKKGSVLQKCLQIMPIIGLFFFFVLILYAYHHGIFRSSTSLQA
                     FIQQFGKYAVMIFVLLQVIQVIIPILPGGISSVAGMLMFGNGFGLLYSCIGLVIGEAI
                     GFLLVRYYGVAFVQLILSPKKYQKFDELLTRKTKDIKKVLVVTLLLPFAPDDLICLVA
                     GLTKLSFREFMQIVIFLKPWSVGVYSMIMLFLFHQAQGHL"
BASE COUNT         7505 a         5559 c         4838 g         8258 t
ORIGIN      
        1 ctttgtcata aaatctttgt aaagcttttt tgttattcaa aactagcggc ttttcataac
       61 cttatttcac gaacatcgca tctccaaaac taaagaaacg atagcgctct tcaatcgcat
      121 gctggtaagc agataaagtc aattctcttc ctgcaaaggc actaactaac atgactaaag
      181 tcgattttgg caaatggaaa ttagttgaga aagcttctac cactttgaat tcatagccag
      241 gcgtaatgaa aatatcagtc catccgctgt ctgctttgat ttctccatta aatttcgttc
      301 caatcgtttc taatgttcga attgaagttg ttccgacagc cacgattttc ccgccatttt
      361 tacgtacttg gttcaatcgc tcagccgctt cttccgtcaa acggtagaat tcactatgca
      421 tatggtgttc ttcaatttta tctacgctga caggtcggaa tgtacctaac cctacatgta
      481 gtgtcagata gactaattca acaccctttg cttcgatctc atcaagtaat tctttcgtaa
      541 aatgcaatcc agctgttggc gctgcagcag aaccattttc tttcgcatag acagtttgat
      601 agcgatctgg gtcttccaga cgttctttga tatatggagg caatggcatt tctcccaatg
      661 attcaagaat ctctagaaaa attccttcat actcaaagtc aatgatccgt ccgccgtgtt
      721 ccaattcttc tttcactact gcttgcaatc tgccatcacc aaaagagatt cttgtcccaa
      781 ctttggcacg tttcgcaggt ttgatcaatg tctcccacgt atctccttgt gtattcgtta
      841 gaagaaggac ttctaaatgc gcaccagtat ctggtttttc tccatataaa cgagcaggca
      901 gaactcgtgt attattcata actagcgcat caccaggctg taactcttca atgatttcat
      961 ggaaatgttt atcttccatc tctccagttt tccgatccaa aacaagtaaa cgagaatgat
     1021 cgcggtcttt taatggtgtt tgtgcgatta attcttccgg caagtcaaaa tcaaaatctt
     1081 ctgttgttaa catatcgtca ctcactttct atcatgtgct tcatcattct atcatgtttt
     1141 tcgttctgtt ggcaaaatca gcactttttc acttctattt tttgttttcc taaataaaaa
     1201 aactacccta tttgtatttt ttcattgttt taggcatact agtaatagat agttcttcat
     1261 tgaaaataga aaaagaggtg gcaccatgat tgaatttcaa aatgtgtcaa aaatttataa
     1321 aggtggaaaa gtcgctgtag aggacgtcaa tctttcattt gaaaagggtg agttcatttg
     1381 ttttatcggt acgagcggaa gcggaaaaac gacgacgatg cggatgatca accgaatgac
     1441 tgatccaaca caagggaaaa ttttgattga tggaaaatcc atccaagaaa ttgatccagt
     1501 ggaattgcga cgtcagatcg gctatgttat ccaaagtatt ggattgatgc ctcacatgac
     1561 gatccgtgaa aatatcactc ttgtccaaaa attgttgaaa gtcagtcaag aagaacggaa
     1621 taaaacagct gaaaaaatga ttgatcttgt ggaattgccc cgtgagatgt tagatcgcta
     1681 cccacatgaa ttatctggtg gtcagcagca gcgtattgga gtcgttcgtg cccttgcagc
     1741 gaatcaagat atcatcttga tggacgagcc attcggtgcg cttgatccaa tcactcgtga
     1801 ttccttgcaa gaccttgtca aagatttaca agagcgtttg ggaaaaacga tcgtatttgt
     1861 aacccatgac atggatgaag cgattaaact agcaagccgt atcgccatca tgagtgaagg
     1921 ccgtgtgatc caatttgata caccagaaaa tattttacgt catcctgcaa acgatttcgt
     1981 agaagagttg attggagaag atcgcctact acaagccaag ccaaatgcga caagagtcgg
     2041 cgaagttatg ctaaatacag caatcacgat tacaccggaa aaatcattac aagaagcaat
     2101 caaactgatg agggaaaaac gtgtagatac gttgttagtt accgataatt cgaatgtatt
     2161 aaaaggattt atcgatgtag aaacgttgaa taaaaaacga ggaaaagtat ccagtgtcgg
     2221 cgacattttg aataaacatg ttttttacgt aaaagaatcc gcctatcttc gtgatacctt
     2281 gcaacgcatt ttaaaacgcg ggctgaaata cgtgccggtc gttgatgaac agaacaaagt
     2341 cgtaggtatc ctgactcgtg catcattagt ggatatcgtc tacgatgtga tttggggaga
     2401 agatcccgca actactgatg ttgcagagtc agctactcct gaagaatcta aggaggtctg
     2461 acctatgcag cagttttttc atcagcacgg ttcagaaatt ctctcaaaag gttttgaaca
     2521 tctttatatt tcaggacttg ctttgatcat tggtatcatc attgctgtac cgcttggtgt
     2581 cttactgaca cgttttccaa aagctgccac gattgtgatt ggcttaacca gtgccttgca
     2641 gacaatccct tctcttgctt tattggcatt gatgatcccg ctatttggcg taggtaaatt
     2701 acctgcgatt atcgcactct ttatttattc attattgccg attttacgta atacgtacat
     2761 tgggatgaaa aatgtcgatt ggaattatcg ggatgtggca aaaggcatgg ggatgactga
     2821 gttccaatcc attttttccg ttgaattgcc cattgctatg ccaacgatca tggctggtat
     2881 tcgtttagct gccgtttacg tgattgcatg ggctacactt gcctcttata tcggcgctgg
     2941 tggtttaggc gatttgattt ttagtggact gaataattac caaccagatc tcattttggc
     3001 aggtacgatc cctgtaacaa ttttagcact attggctgat tggcttctag gtctcttgga
     3061 acaccggctg acaccgatcg cacttagaga ggagaatgaa gaatgaaacg tatactaaaa
     3121 atgaccatgg ttcttttctc tcttcttata cttgcgagtt gttccttccc tggtcttgcc
     3181 agcaatacag atgaagacac catttcgatc acaggtggaa tcacttcaga agcacagatc
     3241 ttagcaagtc tagttgccgg aatggttgaa cattatacag ataaaaatac cgcaatcatc
     3301 aacaatctgg ctactacaac tatcaaccat caagcgatga tgaacggaga tgcttcaatt
     3361 tcagcggctc gctacacagg aacagattta acgactacat tgaaccttcc tcctgaaaaa
     3421 gatccgaaaa aagcgtttgc taccgtgaaa gatgaatttg agaaaagata cggtcaaacg
     3481 tggttcccgt cctatggttt tgaaaatacg tatgtctttc ttgttcgaaa agacaccgca
     3541 caaaaatacc atctatctaa agtcagcgat ctgaaaaatg tagcggatga attagtagct
     3601 ggtgtagata cttcttggat caatcgtaaa ggagacggtt atgacggctt ccaagaaact
     3661 tatggcttct ccttcaattc gatattacct atgcagattg gacttgttta tgacgcagtc
     3721 gaagcaggaa aaatggatat tgttcttggc tactctacgg atggacggat cgccagttat
     3781 gatctagtca tgttggaaga tgatcgtcaa ttcttcccac catatgatgc tgctccagtt
     3841 gtagacaaca agatattagc tgatacgcct catttaaaag aagccttaaa taagttaggt
     3901 cataccatca gtacggaaaa aatgcaggaa ttgaactacg aagcagataa taatctagtg
     3961 gaaccatcag tagtagcaca acgtttctta caagaaaacc actattttga agggaagtga
     4021 agcaattgga taaaatgaat gtctttcaac aatttttcta ttatttccag gaaaatggct
     4081 cctatatctt tgcacaattt atccgtcact tcctgatttc tatctatggt gtcctctttg
     4141 cagcagttgt cgggattccg gttgggatca tgatttctag gagacgtaaa ttagcaaact
     4201 gggtgattcg tttggcgaat atcatccaga cgatcccttc tctagccatg atctccattt
     4261 taatcattgg attaggcctg ggagtcaatg tcgtgattgt tactgtattt ttgtattccc
     4321 tcttaccgat catcaagaat acgtataccg ggatgatcca agtagacaaa aacatccttg
     4381 atgtcggcaa aggcatgggg atgactgcta gacaacgact attcatggta gagttaccac
     4441 tctctgtttc tgttatcatg gcaggcataa gaaacgcgtt agttgttgcc atcgggataa
     4501 ccgcgatcgg tgcattcgtc ggtgctggtg gtcttggaga tatcattatc cgaggaacca
     4561 atgcaacaga gggcacatcg attattttag caggtgcatt gccaactgca ttaatggcga
     4621 tcatcacgga ctggctttta ggtattttgg aaagacggct agatccagcc agccgtacat
     4681 cacgctgatg ttattgtaaa aaacaaaagc ttctgcgacc atttgttggt cgcaaaggct
     4741 tttttagttc tgtcattttt aaggcaataa tccactctga ttcttccctc cttatgggca
     4801 aagagttgct tttcttagct atttatccat tccgtatact ccaacttcat actgccaacg
     4861 ggttcatatc tgcatccacc gactaagttt ttttcttatc cgctaaggca ttttgccaat
     4921 ccattttccc atcactcgtc atggaattca taccacatga tctctaaata ctcgtctgct
     4981 tgttctttga attgggcatc aattcttaca tcctttggcg tggctttcat ttaagccttt
     5041 tccatcagtc ctcgattgtt cgatgccttc agctgcatca tcaaaactgg tgactgccgt
     5101 atcggtaact tcgatcatct tttatacaat cgggaacttg ccatcctcat ccttggctaa
     5161 aaacatatct agccattcca gcttctcgcc atgggaggtt tgcggttcct aaaaccggta
     5221 cacgattctt atggactgca tccgtcgcaa ctagacttgg cgatacgatg atccttcacc
     5281 agaagagcac ccccgtaaac caattgatcg atatattgcc aataagaaaa gacattggcg
     5341 taaaagatat cgatccctcg tgatgcattg ccgttgatac tgctattcat ggccgaaagc
     5401 gccacgactt taacttcttc cgtttgagtg acattcatgt tcggcaatgt cgctttggat
     5461 acccgctctg ctaaaggaac gacactggta ttgtatttcg tatctgtatc ttttccaaaa
     5521 gaccatgcca acgaatcctc tgggaaccaa taagacgact ccggttgatt gtccattgct
     5581 tttttcaaca tacttttggc tgtttctcga taaacgacat ttccaattgt cttcgcctca
     5641 ctttggcgat aatcgatggt cgttgccact gccaacacta acaacgatgc tccaatttta
     5701 ctgattttcc ttgtcacact tcttcctcct tgttttacat aaacccgtca acattccatt
     5761 cctaaactca aacaatgacc cttcaaaggt ggagatatag gaacaaatta aagaaatcat
     5821 gcaataaatc caagaaggtt ggttttagaa caaaaaaaga gtctcctttt tggggagact
     5881 ctttgttaac tatctaaaaa ggttggctct tctcacttca ctcataatgt gtccaggcag
     5941 aataaatttc tacaacttta ttttcctcat caactttgta aaccactcga tgctgtctat
     6001 tcagcctgcg tgagtatctg ccttcatgtg taggtctcag cttttcaaaa gactgcgtgg
     6061 gcatatatgg atcttccttc aatgtctgaa tcacttcttc aaattgtttc tttaaattcg
     6121 tttgcttgat ttttcttaaa tccactttcg cagagttttt gattgcgact gtatagttac
     6181 tcatcaaaga gcttcccaat caatatcatc gatattcgta aagctactgt cgtctttttc
     6241 gcggtctcgt actttatcta aagtacctgt ttgctcaaga aaaagggttt cttgaatcgc
     6301 tctccagtct tccagcccaa tcaatacagc attgtttcca ctacgatcac taataatctc
     6361 gatttcagta tgattttcat ttacctcttt caataactga taaaaatttt tacgagcagt
     6421 gctaggattc atcgttgtat tagccattgt ctctcctcct ttttctgata taattatagc
     6481 gtacttgatt aagtacgtca aaaaaataca ataaagcact taaattcagc aaacttttcc
     6541 tcttttttac atagagaaaa agaccccttt ttagggagga tctttgtcca cgctcacttc
     6601 ttactccttt acgactagcg gtagccaaac gtaaagtaat tggtaacaac gtatcatctt
     6661 tagcaaaggt cgaatccaaa gcctgtgagt ctatgcaaca acaccaatac acgaaggttc
     6721 ctcgttgcag tgtgacttga ttgatatctt gaataacctg aggatacgca cgaaagattt
     6781 gtaacggtta ttcaaaactg attttggccg tcaagtcttc tactgcctca aaaatgattg
     6841 cctctttcgt ctcctgtcat tcatgttcac tatcgatttg atacttgctt agaccgttgg
     6901 gtttgtgaat caccaattaa aaatggcact gagttatggt aacaaaaaat ggtcacttga
     6961 cgaggctgag attcctactt atgaagacac atggcactta agagtcgagg taaaggaaga
     7021 agctgaaaat ataggaggct gtacattatt tggcaaagga ttcggaaatt atgatcaaga
     7081 catcaaaatc aaaatgtttt acagctaaat aggaagaata ataacatttc atacgctgtt
     7141 cccatcttta atggcttata gagggcacct ttagctgaga ataagacaaa acagaccctc
     7201 tagcttcaat taagagctag agggtctgtt tttgatttta aaacttggtt tatttcttca
     7261 aatggtagct ataggtgctg acaacgatat tttcacgcca agacaatcgc aatcttaacc
     7321 gcaaacttgt ttggttatgg agaatattct gccagcgtct gtttggtaca aattgaggaa
     7381 tcaacacagt agttgtatag ttttgtttcg ctgcattttt acttacgata tctacataac
     7441 ggataattgg attttcaatc gagcgataag aagagtggac gattgaaaaa cggacatctg
     7501 ggaaatgctt tttaaattct gcttcgattt ctttttcttt ttcgacatct tcgtctagcg
     7561 aaacatgcat cgcaacgaca taatcaccga tcgaacgtgc gtaattcaac gcaccgatat
     7621 ttacccgtgt cacattcccg actaatacaa gaacggtatt cccgtcataa tcatgtagtt
     7681 ttgcatcatt ttctaaacga agctgttctg ctactttttt ataatgatca tggatcttat
     7741 aaaaaatgaa cataacgatt ggcataatga tgaagaaagg ccaaatgtcc cctaaccgat
     7801 agacaaacaa aatcgcaatg attgcatatg agatgaacgc acccgtaata ttggcaatcg
     7861 atttgcttaa ccatcttttt ccttcttttt tccatttgac gaccatccct gtttgagata
     7921 aagcaaatgg aatgaacacg ccgatagagt ataacggaat caagcgttct gttgagccat
     7981 ggaaaataaa cagcaatacg atcgaaccta gcgctagtgt gataatccca ttggaatagc
     8041 ctagtcgatc cccacgatct tgatacatgt gaggcatgaa tttatctttt gccagattgt
     8101 atgcaagaac tggaaaagca gaaaaaccgg tgttagcagc aactgctaaa atcagcgctg
     8161 tagcaaattg aaggacgtaa tacaaaatac catgtccaaa gacagcttta ccaatttgag
     8221 acaaaacagt gacttctttt tcaggaacga tcccatacca atagttgata aatgtgatcc
     8281 ccacgaagaa gaaacctaag atcaatgcca tcatcgtcaa tgtagcagcg gcattttttg
     8341 ctcttggctt cttaaagaat ggtacagcat tactaatcgc ctccacccca gttaaagagg
     8401 aagaaccaga agaaaatgct cgtaaaatca aagcgataga aacacccggc acagccgctc
     8461 ctggaagtgc agtagcttgc aatggcacag cacctgtcac gatattatat aaaccaacaa
     8521 cgatcagtaa cgagatcaca aggataaatg tgtacaccgg aaataatagg aacgatgcag
     8581 attccctcag cccacgaaga ttcagcatca tcagtagcaa aacgattgtc acagaaatag
     8641 cgacttgatg accgtagagt gctggcaccg ctgatgtgat cgcttcagca cctgctgaga
     8701 cagatactgc tactgtcaac atgtagtcga tcaataaaga gccaccggaa atcaagccag
     8761 cattctttcc aagattctca ctgctgacga catatgctcc cccgccatga ggataagcat
     8821 ggatgatttg acgatatgat agcgttaatg aaatcaataa aataataaca aaagcggcaa
     8881 tgggtagcga ataccagatg gctgcagcag acaaagcgac taaaacgaca acgatttgtt
     8941 ccgtaccata tgcaatagat gataacgcat cagacgacaa taatgccaaa gcagcaaatc
     9001 gggttaattt gtgctcatca ttttcagcag attttaaagg cttacctact aacaaccttt
     9061 ttaagtaatc caatttctaa actcctttac acacaatttt acttcaagtt ttatagtcga
     9121 aaatttatag taaacaagat gttatagtac gctcactgac cttaaaagtc aataaacttt
     9181 aagaaaataa ttggaaaaaa acagaaaaat atcaagcgct ttttcaaacg ctttaataca
     9241 gcaaaaatct aacatttttt tatgggcttt ttctttgaat tctataataa aaggatagaa
     9301 cttgacttag aaaatcaagt tctatccttt ttgatatctt aacttttgga agagagatgt
     9361 aaggctgctt tctacccatc attcttacta ctcgaagcat agcgcagttg tcacaacctc
     9421 ttgataaacg gtgtttaaaa gcttgcatct gcggtaataa gcccaaccaa attaaaaaca
     9481 taagaagctg tttttatttg gtcgttctta ttacttgatg cagagcagct tttttacaac
     9541 ctcttggtac acggtgttca atcagctgac cctcggtatt agctcaaaaa aacggcaaaa
     9601 tatgaggaac tatttttcca tttttttctc taatactcag gtcaaaacac tgatttcaca
     9661 acctcttttt ttaatgaaaa atatggctct catgcgccgc ttctttgaat ttcgtcattt
     9721 tttcttcgat gaacggatag attgccgttc ctacgattcc aaagacaaca aacaaaccga
     9781 tcatgatcca gattgctttc gtagcatttg gccaataaat tcctcctgca gattcccgta
     9841 acaagtttac cgcatgagta aatggcaaga acggattgat catttggaag aatttccctg
     9901 agacttggat cggatagttc ccgcctccgc cagagatcga cagtactaag atgataatag
     9961 cgatcccttt accgacatta tcgaataatg cagccaagac atagacgatc atcatgaacg
    10021 ctaaggcgat caagacagca aatgacacgc tgtagaccgg attttggaca tctactccta
    10081 gtaagaaaat attccctaat gtaacgatca agctttgcgc aatcgccatt gtcaaaaatg
    10141 tcagcatacg agcaacgaat tgttctcgtt tcgtaaaatt gtttcggtct ttctttccta
    10201 aatagtattc tgtcgtagca acacttgaaa gaagaacagc gccgacccac agacatagtg
    10261 cagtataaaa cggggtgcta gctgaaccgt tatttgcgat tggataaagc gcattggttt
    10321 gtagctcaac aggttgtgta aagaagtcac tttcttttgt tgcgtctagt ttcaataatt
    10381 tgatgacttc gcctagatcg acttcttgtt cgccttttcg gatcgcgtct gctgcttttt
    10441 ggataccagc tttgatattt ggccagtcat tgttgatcaa gtccgcagca gcgttcacag
    10501 ctgtttcgac ttctggcatt ttttcattta ctgttgtcaa tgtaccggtg atttcatttt
    10561 ttagtgctgg ccaatcattt tggataaaat cagcggccaa tcctaatttt tgctgaatga
    10621 tcggtaattc attgttgtat aggtctgccc cttcattgat gccattgacg atggtatcca
    10681 tatttccatt cagcattgta ttggcatcat ggatttcttg tccaattgca ggcatttctt
    10741 tttgatattt ttctaaaatt gccactgcat tcgttacagt tgctttcgtt gagctgagaa
    10801 gcgaatcaaa gtcgatctgg tccgctttgc tcagtgcgcc ttgtgcagtc ccaatcgtat
    10861 cgatgacttg gtctagtaga gaagtgacag tggaactgat ttgacctgta ttgataccag
    10921 caatgatgcc attgatatta ttaacaacgg catcaatttg atctagcaat tcatcaatag
    10981 ccttcgtgtc ttcattttga acagctgtgt tcaaagcaga taggcggttt tgcagattgc
    11041 ttagcaaggg ttttaattga tttagctgat caataattgg ctgtaatttc gtatttccag
    11101 cacttgtttg caatttagtc aggaactcga ccagtttatc gattgcattt tgttgttgag
    11161 atattccgtc aataaagccg ttcaatacat tgctgatgtt tttcttttca tcatcagtca
    11221 gcttaccatc ttcaatagct gttcttacag tatctattaa cgaacctgtc gttgttgcca
    11281 cttgtccaat tgacttcaat gtaacatcta cactgtttgt gatgcttggt atcgcatctt
    11341 tcagctgaga ggcacctgat tttgtttggt ttgctagatc acttgcctga ttttctaaat
    11401 ttttcacatc tggcaagata tcttgtactt gttggatgat cgtcaagcct tgttttgctt
    11461 catcgattcc ttggttcatt gtctcttgga tcgaagcaaa atcgccgtcg atctctgcta
    11521 gttgcttacc ggcattttgg atctctggga ttttttcttg caaatcaagg atgatttttg
    11581 cttgatcttt caactcaggc attttgtcat tcaatgcaac gactttttca cccatctcat
    11641 ctactttagg gatgtaatcc acgaattcat ttgctttatt cagtttttcc ttgatttcag
    11701 gtagttgact ttgtaattcg aggacttgtt ttgtgtagcc gtcgatcgtg tccaaatttt
    11761 catctgttga taaaatcata tctttaactt tattgatact tactaggttc gtatcgatgt
    11821 cgtaacctat ctcattgaat actttcaata aagtcgaact ggctgttttg ataaattcat
    11881 ttgtgatttg cgattggatc gaacttgctc ctttatcggt gattttcggt gcaatcgcat
    11941 tgattttttc atttaccgta tattcgattt ttggtttctt gatatcacca ctagtaaaac
    12001 tcagcagatc ttctgagaaa tcctttggca agtaaatacc tgcgtaatac tttccggaac
    12061 ggactccgtc ttctaattgt tcttttgaat caacgaattg ccatcctaat tgtttatttt
    12121 tatgaagcga ttcgatgact tgctccccaa tggccacttc tttaccttga aactctgctg
    12181 gcttgtctgc actgtaaaca gcaattggca gctctccagt atttccatat ggatcccata
    12241 atgctttgat gttaaaccac gcatatagcg aagggatgat catgatcgcg atgatcagaa
    12301 gtgttgcaat cgggtttttg aaaatccgtt tccagtcaag caaatataat cgaagcgtat
    12361 ttttgattga ctgcatagtt ctcccccttc ttcttttttc agctgaatta ctttaccatg
    12421 tatttcatac ttttttcaat cggctttttt caaaaaagtc gaatttttgg acatatcacg
    12481 gcaattgtct cattgtaatc tcttacatat tgagaaataa ttaaggatta cagcctttac
    12541 tttatcatga aataaaaggg aaagataatt ttatgccaaa gtttttatct attatacgta
    12601 tacgcaaaaa agctaaaaca ttttttgtct ttgcccctac aaaaatgttt cagctttttt
    12661 cgttttttat tcctgtattt cttatttttc gaatgacagg atgattttcc cagcaggagg
    12721 atgtccttca actagctgat gtgcttggat gacatgctta agtgaagcag acagattcat
    12781 tgaaataaaa acatgaaagg ctcctttttg gtaggctttg attatgccag caaaggcttc
    12841 tgcatctaga tattcctttc ttggaacaaa cgattcataa aagccttcct ttttttgccg
    12901 caaatctaga tctgggaggt catttaatgc aacatacctg ccgcctggtt tcatgatctg
    12961 gatgccggtt tctcctttga tacttccttt cgtcgcatcg attacaaggt ctgcctgatc
    13021 agcaaattgc agacctggat ttgttttatc ataagcagca aatgctgaag ctcctaattt
    13081 ttttaccttt tcctcatttt tactggatgc actggttaag attcggattc ccttttcatg
    13141 gagaagctgg atcagacttg acccgaccgc acctgatgct cctagtatca ttacagtatc
    13201 tgtcggctgg atttccgtca aatggttgat tagattataa gccgtaattc ctggcgtgac
    13261 cattccggct gcttcttccc aactcatttt atctggaatt tttgctactt ttgctgatgg
    13321 caacacgact tcttctccgt aagtcccgcc gactgcatgg acagctactc gatcacctac
    13381 atgaacagtt gtgacatctg aaccaatctc tgtcacaata ccagcgccat cattacctgg
    13441 tacataaggg aatttcaatg ttcgtatctc tttcatttct cctaaacgca aggcaacatc
    13501 ataaggattc acactgaatg cttttatttc tacacgaaca tgtccagaac cgacttctct
    13561 gggatgagca tcgatttctt caaaaacatc ttgtgcttct ccgtaaccgt taattgcaaa
    13621 tcttcgcatg gtcaccatct ccctttttct ttaagtttac gtttatgtct ttattttgac
    13681 aaaaaaaatg tcttttcgtt ttggcgcatg attcaaaaca aaatagttgt cttttttcgc
    13741 gtaacgtgtt aaattattta tctaaaagcg taaagattac gatttacgct aataaaaaat
    13801 aattggagga atttgttgat ggctaaaaaa tcaaagattg ccaaagcaaa aaaacagcaa
    13861 gaaacgattg aacgctatgc tgctttacgc caggaattaa aagcgcaaaa agattacgaa
    13921 ggcttgcata aacttccttt agatgctcgt ccagaacgat tgaaaaatcg tgatttaatc
    13981 gatggacgcc ctcgcggata catgcgtaaa ttcgggatgt cccgtataaa attccgtgaa
    14041 ttagcacata aaggtttgat tccaggagta aaaaaagcca gctggtaatc caagtctggc
    14101 tgtaatgtaa aggaggaggg cgcatggacc actccttgga tcatcaaaaa agatacgttc
    14161 gcttcttcta gcagaaatgc tggtactaga agcagacgta tcttttttta cgcacagctg
    14221 gtcctttttt atatgtaaag gctgcatggt tacttcgcta tatttattta gtaacaggag
    14281 tcagtgcttc gatacccaca ctaattttca atgctcggtc aacttctgcc ataatgggtc
    14341 gatccaaatg gcagaccttt tctttcaatc ttgatttatc gatcgttctg atctgctcca
    14401 acaggataac ggagtctctt tctattcctg ttccagtagc tttgatccca atgtgagtcg
    14461 gaagcttagg tttagccatt tttgccgtta tggccgcaac aatgatcgtc gggctaaaat
    14521 ggttacctag attattttga ataaccaaaa ctgggcgtgt tccgccttgc tccgatccca
    14581 cgactggaga aagatcagca aaataaatat ctcctctttt taccatagga tcctccttat
    14641 tcttgatatt ctcttggtat ccgctgtcct aatccgcaag ccacttcata gtggatcgta
    14701 cctaattgat ctgctatatc ctgcatagtg atttctttgt ctgcattttt gccgataagc
    14761 gtcacttttg ttccgacagg aaattcttga ggcaatcgga tcatcagttg atccatacat
    14821 acacgcccaa tcgtttcaca gtagttccct tctaccaata gagaaaaacc ctgcatcttt
    14881 cgtggccagc catctgcata accgatcggt atcgttccga tccactctgc ttcaggagtg
    14941 atatatgttt ctccatagcc gattccttca cctgctggga gttttttgac ttgaatcaat
    15001 tcagaaacca gctcaagtgc tggctgcaat ggataaactt ccggtagtgc gtgcccagag
    15061 ggattaagtc cgtacattgc tactccataa cgaatcatat tgccgattgt ttcatcatgc
    15121 cataaagccg ttgcactatt gctgacatgt acatatcgag gaagttcggg aagttttttc
    15181 agcacttcta taaagcgttc tttttgcaga ttccaatatg tatcatctgc ctgatctgct
    15241 gtagaaaaat gggtaaataa accttcccat tctaatacac gactttcttt gatgaatgca
    15301 gctgcctctt ttacttcttc aggtgtacaa aatccgatac gacccatccc agtgtctgct
    15361 tttagatgaa tcgaaagagg cgtctctagc ttacttttct ctaaaacagc agctgctgct
    15421 tgcaaccatt cccgtgtacc tgcagttact gataaatcat gagcaacagc tacagtcagt
    15481 gcgtcgtaag gaaccatatt caagataagg atgggctgag taaatccagc ttctctcaac
    15541 tcgactcctt catctaaatt tgaaacacaa aagcccgaag ctccacctgc aactgctgcc
    15601 tcagctgttt caatagctcc atgaccgtat ccgttcgctt ttactactgc aaacaattct
    15661 tttccttgcg gaagtcttgc aacttcattt gctacatttt cagttatagc ttttttatgt
    15721 atcactgctt tcgttgggcg gtgccaagcg acaaccatcg tttttccttc tttctagtct
    15781 tccaaaataa tttgtgcaaa agctgtttca tttgtatgag taatactgac ccatacattg
    15841 ccttcatgag gtgaacgcgt cacaacaggc tgaccatttt cattttttaa aatctcgaca
    15901 tcttgaaagg taacttttcc gatcccagtt ccccaagctt tagagaaagc ctctttgcaa
    15961 gcgtaacgcc cgcctaaaaa ttctacttgg cgatgaaaag gcaaggactg gaatagtttc
    16021 atttcatcag aggtcaagat tcgtgcaatg aattttggtt tttcttcgat cagccgagtg
    16081 atcctaggaa gttcgactgc atcgatccca attcctttta tcatatgctt ttctcttttc
    16141 aataaattta gaacactctc attctaccaa attataacca ttttgccaca aataagtcca
    16201 caaataacaa aaatgaaagt ttctcttaaa aaagagaaac tttcatttta tgtttaatcg
    16261 ttatttgaac ggattacaaa tccgcgtttt ttatcattgt gacgtttacc gccatctttt
    16321 tggctgttat tatttttgct ataaccgcct tttgatttgt ttccacgata attaccgccg
    16381 tcacgacgat tacggttgtt tccgccacca cgtttgccat ttttattgta tccttttttc
    16441 tgcattggca atgggcgttc tggtgtgatc ttcactggca ctgcatcagc tggatctttt
    16501 gctgtcgttt ttagcaaaag tgcaactaaa tcttgtgcag aatattcttc taataattta
    16561 tctgctgttt gcaggtattt atctagacca ttttctgcaa gttttgtttc gatttgttca
    16621 actgcagcac ctaattgacc tttgaatgct tctttttcgg ttggtggacg taaagtcgtc
    16681 atccgttttt tcgtcaagtt ttcaatcaca tgcaagtagt ccatttcatt tggtgtaacg
    16741 aaagtcacag acataccgcc ttttccggca cggcctgtac gtccgatacg gtgaacgtag
    16801 ctttctggat cttgagggat atcatagttg tacacatgag tgacacctga aatatctaat
    16861 ccacgtgcag caacgtctgt cgctacaagg atatctaaat gaccgctctt aaatgaacgc
    16921 aatacgctca ttcgtttttg ttgagacaaa tcgccatgga ttccttctgc acggtaaccg
    16981 cgtgcttcta atccgcgtgc caattcgtct acacggcgtt ttgtacgtcc gaagacgatt
    17041 gttaattcag gtgtttgaac atcaaacaag cgagtcatga tatcgaattt ttcgtattct
    17101 tttgcgcgga catagtattg atcgatcaag tcagctgtca tttctttcgc tttgatcttc
    17161 acatgatgtg gatttttcat gaatttaacg ccaatattct tgatagctgg cggcatcgtt
    17221 gctgagaaaa gtaatgtttg tctttgatca ggaacttgtg aaatgatttt ttcgatatct
    17281 tccaagaagc ccatattcaa catttcatct gcttcatcca aaactaatgt ttgaacggtt
    17341 ccaagtttca atgtgtggcg gttaatgtgg tcaagcatac gtcctggtgt acccacaacg
    17401 atatgtggac gatctttcaa gccacggatc tgacggccaa tatctgctcc gccgtaaacg
    17461 gcttgtacac gtactttttt gtcgcgccct aaacgatata attcttcttg tgtttggata
    17521 gctaattcac gtgttggtgc gataactaaa ccttgtaatt cgtgacgatc tggatcgatt
    17581 ttttctaaca ttggtaatcc aaatgcagct gttttccctg tacctgtctg tgcttgtcca
    17641 ataacgtctt ttccagctaa tgctagtgga atcgtttctg cttggatagg cgttgcttct
    17701 tcaaaaccag cgcgttcgac tgatttcaac aattctggtg ataattctag ttctttaaat
    17761 ttcaaatgaa tcctcctata tggttgttaa ctgaggatgt agcttttttg ctaccccgtc
    17821 gatttgttcg gtcaaagtgt attgtttctt tttgacagtg gccacgcacg tttttatcca
    17881 ttcttagccc ctgtggcacc accgaaaaat cactttgcga agtttaggca ttagaaaagc
    17941 caaacgggtc gcgttcagct ttatcattat tatgacatct ggcttcaaca agttgtttct
    18001 atggcaaaac cagtccaatt tctcttcatc tttcggcaat aggttattct aacatagttt
    18061 ttcgttttct gcaagtttac agatttttat ttcatttgct gaagttgttc taccacttca
    18121 aataagccca tgctgttgct gccttttagc ataatactat ctgttgctgc aagattttgt
    18181 ttgatagcat caatcaattt attcttttct ttttcaaaat agaacacagg tagttggggg
    18241 tatttttggt tcaattcttc ttttagtgca tgcatttgtt ccccataaag gaaaatcatg
    18301 gcgaatttct caggatcgat atgttcactc atttgcgcat gcatatttaa agactctttc
    18361 cctaattcca gcatatctgc taacacagcg attctgcgtc cttttgttgg cagattttta
    18421 aaagtatcta ataccagtcc catggctgtt ggatttgcat tgtagacatc gctcaaaata
    18481 gctgcaccat ttcctgccgt tagccattcg gttctgtttt gagtgataga aacatgggcg
    18541 agcccttggc gtatctcagg tatggacagt ccaaagaagc gcccgatcgt atacgcaatc
    18601 aaagcattcg ttacattata acttccaggc agcgggatcg taaatgtttc tccttctact
    18661 acaaaatcgg tttgtgcttt tccttttgct gtcacttccg catgaacatc gccatttcca
    18721 ataccgaatg ttgtgactgt ttgtactaat gttgccgtta aaggtgtcag caacggttca
    18781 tctgcgggca caacgagtaa tccgtctgat acaagtccgt cagtgatttc cattttggct
    18841 ttagcgattc cttctcgcga cccaagattt tctatgtgtg cttcaccgat cattgtgatt
    18901 gctgcagctt ttggttgagc cataagtgaa agttccgtga tttcattggc gtgatccatg
    18961 cccatttcca aaacgatctt ttctgtatct tggggcatgt gcaaaatcgt gtaaggaaga
    19021 ccaatattat tgttgtaatt tccttgcgtc ttatatgttt tgtatttttc agacaagaca
    19081 gacgcggtta gatctttcgt ggtggtttta ccattgcttc ctgtaattgc aacgacttct
    19141 gcgcctactt tttccaagta ataggttgcc aattgctgca tggctttcaa aggatctgct
    19201 acaggaataa ctggaaaatt ttttggagct tgttcaacag gcaagctcca aaatgaagca
    19261 gatgctccgt ttgtgatcgc ttgctggata aattcatgtc catctcgcgt accagcaaga
    19321 ggaacgaata aacttccttc ggttatcttc cggctgtcaa attcgacatt ggtaatcttt
    19381 gtcagtgcag agcattcgct gcccacggct tgtgcaattt cttgtattgt tagattcatt
    19441 gagatctctc ctaaaaaagg ttgtgaaaaa agcgtttggc ctaaacggcg ggttcgcatg
    19501 actctcactt ccaagtaaat ttctctattc gtatttagaa gctagaatga acgcggttac
    19561 gcaatcactc cagcctcttc tttatttctc tttattcatt tttttcaaaa aaagattgac
    19621 gctgatggta tcgattcatt cctaactgga tcagttcttc aatcaaatca ccgtatttca
    19681 agcccatatt ttcccataag agtgggtaca tactgaactc cgtaaatcct ggcatagagt
    19741 ttaattcatt caggaataat tcatttttat ttgtcaaaaa gaaatcgcac cggctcaatc
    19801 cgcttccacc taacatcgtg taagctaact tcgcgtactc ttgcgctttt tgataaactt
    19861 cttctggcac ttcggctgga atctgcattt cgattttatt attgatatat tttgcttcat
    19921 aatcatagaa tgctacgtct tttacgactt caccaggcaa agtcgtccga acgtcttcat
    19981 ttcctaatac agcaacttcg atttcgcgcg cttcaattcc ttgttcaacg attgctcgag
    20041 aatcatactg ataggctgtt gctaaagcat tttgcagctc ttctcggttt tctgcttttg
    20101 taatgccgac actagaaccc atattcgccg gtttgacaaa catcggataa agcaaagaac
    20161 cttcacattg atcaaatact tttttaggat tttctttcca ttgattctta agtactggta
    20221 cataaggaac ttgcggcaca ccagcagctt gtaaaatata cttggtcatg attttatcca
    20281 tggcacatgc actggtcaat acgcctgcgc cgacataagg catattcaat gtctctaaga
    20341 agccttggat cgttccatct tccccgtttg gcccatgtaa aactggaaaa acgatggctc
    20401 cttcttcttt gatttcgccc ggattgatca cttttcctgt aaagccttcc tctgtctgtc
    20461 cacttgggtc ccatgaaaga tgcaagacat ctttgctggc aggtttttct gttagtaatg
    20521 gacctttgac ccattgtcct tcttttgtaa taaatacgag ttgaacttgg taataattat
    20581 aataaatggc atttaaaact gaaaatgcgg aaagaatgga cacttcatgc tctgcgctgc
    20641 gtccgccata tagtaaagta atcttcaaaa gattgtcctc ctgtattcta aatcgttcag
    20701 tgatttactc tcatatttta gcacaaaaca aaaataaacg aataacttat ttataaaaaa
    20761 acgagccagc ttctaaaaga acgagcgtca tttatttttt gtcagctaga ttatttgtcc
    20821 cgttttttat aaaaagttat gataaagaaa aggagggatg atgatggcgc aaacaaatcc
    20881 acgcagccgc ttggcagaaa tcattcgagt gttcatcaat tacaatgtag tgccaaactt
    20941 tgtacagcaa aaaaatcccg aacaggtaaa aaaagccttt gaagaactag gccccacctt
    21001 catcaagata ggacagatgc tttctgttcg agaagatttg ctttcttctg ccttcactca
    21061 aacattcaaa acattacaag atagtgtacc tagcgacaca ttttcaacgg tcaaaaagac
    21121 gatcgaaaca gaactttctc tttcattatc agatatattc gatgattttt caaaatcgcc
    21181 ttttgcctct gcttctatgg ggcaggctca tcgtgccaag ctgaagaacg gtgacgcggt
    21241 agtcgttaag atccaacacc ctaacatcgc cgaagagatc cgacttgatc ttcaactatt
    21301 tgaacgagcg atccctttga tcaaatacat tcctgaaact agcgtagttg atctaaaagg
    21361 ggtactccaa gaagtaaaac gttccttgat caatgaaatg gacttcttaa aagaaagtca
    21421 aaatggcgaa caattctatc aaaagaacaa tggctggaaa gagatccgca gccccaagat
    21481 ttatgacgct ttttgttcga aaaaagtgat cgtgatggaa gaaatgtctg gtaaaaactt
    21541 gaatcattta atgaacgccg aaaacaaaac tgaaactttt atcactggaa ttcaaaacaa
    21601 gcagctgaaa caagaagttg caaagctttt agttgagaac tttatgaaac aggtgtttga
    21661 tgatggtttt ttccatgctg atcctcatcc agggaatctg ctattccatg tactaacaaa
    21721 agaagaacag acacaagcta gccgaaaaac tgaaacagtc catgaaaaag agttcggttc
    21781 ctttgctttt cgagcctcca cttctgcaga agaccctgtt gcgccatata ccatcaacta
    21841 catcgatttt ggtatgatgg ggcatctttc tgcaggactt aggcaaaaac tcacacaagc
    21901 cgttttagcg ctgtatacga aagatgctta tcgaatcgaa aaagcggtcc ttcgactttg
    21961 tcagcaagaa ggctcgtttg atgaaagtcg gttccaccaa gaactgacaa gttttcttga
    22021 acagtattat gattctccta ttgatgaaat caacttgcaa gaagtattca cacatgtcgt
    22081 gacgatttgt catcaaaata atctgcagtt cgatcgtgat atcacgcttt tgctgaaagc
    22141 atttgggaca ttagaagggg tgatccgcgt cctcgatcct gaagtttccc tcatggaagt
    22201 cgcttcgcct tttgctcaac attattttct cactcatctg gatgtagaag atacattgaa
    22261 acaaagcgga ttagacttat tggaagggat gaaggctgcg cctaagatcc ctcaacagct
    22321 ccaccatcta ttagaaatgt ggacttcggg acaaggaaaa gtcaatttgg aattgaaaaa
    22381 gcaagacaaa ttattgagca ggatcgaaag tatgatcaat cggcttgttt tcggtatgat
    22441 tttagctgca ttgatcgtag ggtcctccct gcttgtccaa gcagcacctg tagaaaacgc
    22501 agaggtcgtt tccttattag ggatatttac gtatgctatt gccgcattcg tcattatttt
    22561 tttggcaatc gatgcattga tccaaatgta taagaagagg aaaaagtaga aaaaggttgt
    22621 gacagaaaga atcagcttca agaaataaga aggggtttta cataaattgt ttctcaaatt
    22681 tttgtgaaaa ttcggcttat ttttcgaaga ggctacttct gaaacaccga gaataaaaaa
    22741 tgtgaaaaag ctgttctgca cccagtaata agaacaatca aaaagggaac atggaacaca
    22801 tttatcctgt ttccctgttc cctttttgat gtattcgagc ataaataaaa taccttcgtt
    22861 acctactatc ttctgtactt ggtaaacctt agtcaattgc cttttttaac gcttgacgaa
    22921 aagacatatg atctttctcc gtaaagggtt ttggaccctt tgtccttatg ccagcttttc
    22981 ttaactttcc actatgataa cgttgttcta gaagcgtgcc gatattcgct tcgtcaaatt
    23041 cttttccaga gtgatggaac actcgcacac ccttcggcaa tacaagtgaa gctaaaccat
    23101 aatcttgcgt gatcaaaaag tcattcttct taaccatacc gacgatttta taatccgcac
    23161 tatcagctcc gcggtctacg tagacgattt ggacatgatt agcgtattct ttggtcgtat
    23221 aatggtccac actggtcacg ataaccacgt caagaccata ggattctcct aattttatga
    23281 catcttcttt tactggagaa ccatctccat caatgaatag cctcattctt tttcgccttc
    23341 ttccataaat gataaacagt tactaatccg ctcagtaaaa gaccaacatt gatccatttt
    23401 gccaagataa gcagttgtac actttctatc ggcactgatt catggttcag cgtgatcaat
    23461 aatagatgga ttggctctcc catttctttt gctaaaacaa acaaaagcgt catcaataaa
    23521 aactggtgga tcacactccc tttattttga gtagtatact tgacaacgat ccggcgatcc
    23581 attggaatag ctgtatcagt ttgataatat tccttattta gccagctgcc tgttactacg
    23641 tgccagaaac taagcagaaa gacacctatc gcaaaaccat ttggaatcaa gaggaccaat
    23701 aaagaagaac tcagtccaag caattgcata gccaatggag accatgttaa acgtttcaaa
    23761 atccatggtc cgactatttt tgctgcaatc aagcctgctg cataaggcaa atacataaaa
    23821 atcgaaagtt tttctaatcc gtacagtatg ccaacataaa aactgctaaa taaaaaaagg
    23881 aaattcccta gcattccatt tagaaaagta aacagattta gccagcttgg caacttccat
    23941 tccttcttct ggtgtcctaa aacaaacacg aacaagatga acagcagcaa gaaaccataa
    24001 atagcaagat caaaaagcct ttcatcgaat aacaatcggg catttctcaa aagaaacaat
    24061 aagccaaaga atatcaaaaa taaaacaagc tctcgcgtag ctaccagatt tcttttgatg
    24121 tctttgaaat ccagttcgta acgcggataa tgactaaccg tatggtaggc catgacgtaa
    24181 aaaagtgtat aaatagtaaa gcttgctgca atctgagtcg gtgcaggcaa ctcaatcgct
    24241 tgatacagga gaaatagcca gatagctgca aataagtact ttttcccatc catattgata
    24301 aaaccttgcg tcttttcgtg aaaattgacc gtggtattag caggtacaag ccatgctgca
    24361 ctcagcccta gcaaaacact tgaaaaataa aataaaggaa aataaaatac gcctaatatt
    24421 ccaagcaatg aaccagcacc accaatcagc agagcgatca tcagcaacgt gtaactatct
    24481 agaccaaatc gtagactgtt gactaaaaat agtccagtca tccgaaaggc ataaaacagc
    24541 gtaaatggca aaatcgtcag ccaattatgc gagtctgtta gtcccaaaaa taaaagataa
    24601 ggaataaaaa taaccgtgtt acttaagata aagggcgttg tttgtgtaaa attacgccca
    24661 aatcgtttga gtttttcgaa catgacaatg gctccttaaa cagtcttata actaatctgc
    24721 tcttcgattt tagcattaaa ggggaaataa accaatttta cagaatatat tcttgtaaaa
    24781 aaaaatacag aaagaagcat aagcttcttt ctgcattttt acggtacttg attactcaag
    24841 cagacaagcc cttctccaca aaagtcttgc ccgacacccc tgcatccggc aggtgataaa
    24901 gatagaaatc aattatcctg tgcctccaaa atcaattagg agctctgtaa accagagtcc
    24961 ttctcgaccc gtcgcataaa tttactttaa cacagttcct atgtttatgc gagagctttt
    25021 ttcattttat aatcgaccat ttgaaatcct tgaccgatat ctgaaataag ttcttctgta
    25081 atctcaaatc cttcatgctt ataaacctcg attgcttgat gattcccctg attcactcgc
    25141 aaaaagatct ctctttcctt tgtttgcgca gcaagttctt cataccagcg aaaaactgaa
    25201 gaagtcaatc cttgaccacg tactttattt agcaaatata atttacttaa ataaattttt
    25261 ccatttatct cttcataagc agtgtaaccg acagtctttt cttcgctttt taataaaaag
    25321 taggacacac cttctgtcag ttctttttga atctgttttt ttgactgata agttttcagc
    25381 atgtaatcca cttgtttttg accaatgatc ggcacaaaag cttccggcca tacttcttgt
    25441 atgactgcca tcagctcatc cagttcattt tctgttactt ttattttttc catacaccca
    25501 cgtccttttt tacattataa atgaccttgc gcttgatgga ataaaaagag catgatcatg
    25561 ctatacacac ccaccgacca tggtttcaag aaaatcacaa tctgcataaa ttccctaaaa
    25621 gataatttcg tcaaaccagc tactagacag atcaagtcgt ctggcgcaaa gggaagcagc
    25681 aaggtaacaa ctagtacttt tttaatatct ttcgtttttc ttgtcagcaa ttcatcaaat
    25741 ttctgatact tttttggcga taaaataagc tggacaaagg ctacgccata gtaacggaca
    25801 agcaaaaatc cgattgcttc cccaatcact aggccaatac aactatataa aagcccaaat
    25861 ccattgccaa acatcagcat gcccgctact gaggagatcc ctcccggcaa aataggaatg
    25921 atcacttgga tcacttgcaa cagaacaaat atcatcactg catacttgcc aaattgctgg
    25981 ataaacgctt gcaaagacgt gctcgatcga aaaatcccat gatgataagc ataaagaatc
    26041 aacacaaaga aaaaaaacag accaataatg ggcatgatct gaagacattt ttgtaaaact
    26101 gatccttttt tagacatcta tattccccac atcttttttc atttattaaa actgcctcct
//
LOCUS       DAZKKZ010000041        25651 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.042, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000041 DAZKKZ010000000
VERSION     DAZKKZ010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 25651)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25651)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25651
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.042"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(88..1668)
                     /locus_tag="ACG8LA_001811"
     CDS             complement(88..1668)
                     /locus_tag="ACG8LA_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HFQ0204107.1"
                     /translation="MNNPKLKQQVDNRRTFAIISHPDAGKTTITEQLLLFGGAIRQAG
                     TVKGKKTGNFAKSDWMEIEKQRGISVTSSVMQFDYQGKRVNILDTPGHEDFSEDTYRT
                     LMAVDSAVMVIDSAKGIEAQTKKLFQVVKKRGIPIFTFINKLDRDGREPLELLEELEE
                     LLDIESYPMNWPIGMGKGLEGLYDIYHNRVEFYRPENYQDERLVELDEDGLLPENHPL
                     TENSLYEQVLEEVELIKEAGDAFNQEKIARGDQTPVFFGSALTNFGVQTFLETFVELA
                     PAPYGHKTQDDQMVSPYEEEFSGFVFKIQANMNPAHRDRIAFVRICSGTFERGMDVWL
                     ERTNKKLKLSNVTQFMADSRENVEKAVAGDIIGVYDTGNYQIGDTLFEGKLKVAYEEL
                     PSFTPELFMKVTAKNVMKQKSFHKGIYQLVQEGAIQLYKTYLTEEYIIGAVGQLQFEV
                     FQYRMLNEYNAEVIMSPMGHKIARWIDPEDLDEKMSSSRNILARDRFDQPLFLFENQF
                     AERWFADKYPNVKLKSLM"
     gene            complement(2069..3445)
                     /locus_tag="ACG8LA_001812"
     CDS             complement(2069..3445)
                     /locus_tag="ACG8LA_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016610209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin family protein"
                     /protein_id="HFQ0204108.1"
                     /translation="MNADPESQSLLAQILLLIVLTLINAFLAASEIAVVSINKNRIEQ
                     KADEGDVKSQKLLKILQNPNNFLSTIQVGITLVNILSGASLANTLSERLAPVLGGGTA
                     AKNIANIIVLAILTYVSIVFGELYPKRIALNKSEEVAKFTSGLIRLIGVVAKPFVWLL
                     SASTSLLARITPMTFDDEDSKMTRDEMRYMLENEGVLNNEELEMLQGVFSLDTKVARE
                     VMVPRTDAFMIDINDTVEENVNEVLSENYSRIPVYNEDKDKVVGILHTKNLLKAAHKF
                     GFDNLDIKKIMQEPLFVPETVFIDDLLYEMKKTQNQMAILLDEYGGVVGLATLEDLLE
                     EIVGEIDDESDEVENLYEKIDEHEYIIQGRMLIDEFNEAFDSDLHMSDVDTMAGYLIT
                     ALGMIPDEGEKLSFDVDNITLVSEEMEGSRILKIRVIFHDPEETEAEPEEERRYFRKE
                     FEDDEPRR"
     gene            complement(3573..4661)
                     /locus_tag="ACG8LA_001813"
     CDS             complement(3573..4661)
                     /locus_tag="ACG8LA_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HFQ0204109.1"
                     /translation="MFWSLELLIIAALIMISSEINFIFEPIGTFFSTLFAPVLIAGFL
                     YYLLNPIVKLLMKAKIKRIWAVAIVLLLLVAAIIWILLSVIPSLVQQISSLASNMPDF
                     IKQVESWLKEVAELPLFKEVDINKYFEQLDISYGTIIQQFLSGVSNSLGSIVGTIASA
                     TVVIITAPFILFYMLKDGEKLVPNIQQFFPEKRRNQIVELLGQLNKTLANYISGQAIE
                     CLFVGTFTFLGYMVIGVDYAFLFGVIAGLTNLIPYLGPYLGLAPAFLVTVFNDPVKAL
                     LCCVVVLIVQQLDGNIIYPNVIGKSLKIHPLTIIIVLLVAGNIAGLLGIFLGVPFYAI
                     CKTIISYIIKIVKEDKQNENKKKIATTS"
     gene            4833..5267
                     /locus_tag="ACG8LA_001814"
     CDS             4833..5267
                     /locus_tag="ACG8LA_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFQ0204110.1"
                     /translation="MKVVQTKDTMSNIYLDAVRIRHQVFVVEQGVPLSREIDKDEAHC
                     IHFVLYSDKKEPQGTVRLLPLENGKMKLQRMAILSEYRHQGLGKILIEEAENFAKNQG
                     YNTILLGAQSTAETFYEKLGYTAYGDPFEDAGMPHIYMKKTL"
     gene            complement(5345..5878)
                     /locus_tag="ACG8LA_001815"
     CDS             complement(5345..5878)
                     /locus_tag="ACG8LA_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HFQ0204111.1"
                     /translation="MGVPKEGEFVTIQSYKHDGKLHRTWRDTMVLKTSEHSMIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNVIAMIREKGVSYYCNLASPFLLDDEALKYI
                     DYDLDIKVFPDGEKRLLDVDEYEMHSKMMNYPNDIDFILKENVKILVDWINNGDGPFS
                     EGYIDIWYNRYKQLSRK"
     gene            complement(5972..7150)
                     /gene="mutY"
                     /locus_tag="ACG8LA_001816"
     CDS             complement(5972..7150)
                     /gene="mutY"
                     /locus_tag="ACG8LA_001816"
                     /EC_number="3.2.2.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0019104 - DNA N-glycosylase activity
                     [Evidence IEA];
                     GO_process: GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HFQ0204112.1"
                     /translation="MNKEWEKWTDKETKEFQDQFIQWYEQEKRNLPWRYNRDPYRIWI
                     SEIMLQQTRVDTVIDYFYRFMEWFPTIEELANAPEEKLLKAWEGLGYYSRARNIQAAA
                     KQIMSEFDGEMPQTPEEISSLKGIGPYTTGAIASIAFGLPEPAVDGNVMRVVSRLFCI
                     EADIAKASSRKIFDEAMRKIIDEKHPGEFNQAMMDLGSAICTPTSPKCETCPIQAFCL
                     ANKRGIQTSFPVKTKKAKPKDVYYISAALQNHSGAYYFEERDSQKLLANMWTFPMMEV
                     TQEEYERLKKEWETKPEIDLFDDLVAEEEQNLPFEKQELFVWQTRHLGEVTHIFSHLK
                     WHVLLFYGRATEGAEQEFTENKTSKWLKPDAFDSVVFPKVQMKLVDQLEKNRNNRNPF
                     "
     gene            complement(7143..7940)
                     /gene="recX"
                     /locus_tag="ACG8LA_001817"
     CDS             complement(7143..7940)
                     /gene="recX"
                     /locus_tag="ACG8LA_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006282 - regulation of DNA repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HFQ0204113.1"
                     /translation="MLTVTRISKGKGPFYRVDLSEGEALQVSEDVLVRYRLLKGRELD
                     EETIQEIKKSSGADFGFHLAMNYLSYQLRSEKEIRTYLKEKEILQEDRNKIVARLKEL
                     DLVDDLVYGESYVRTNMRLSDKGPKKLAQQMQQKGLKPEIIEQALSQYTFEDQVQNAH
                     QTAEKAFGKNHGKSQKELLRKIQQTLMTKGFSQEVIQQAIADLPQEADQEIEYDYLVK
                     QGDKLWRRNLRFEPKKRNLKVKQSLYQKGFDLDMIQRFITEKEEESE"
     gene            8047..9429
                     /gene="rlmD"
                     /locus_tag="ACG8LA_001818"
     CDS             8047..9429
                     /gene="rlmD"
                     /locus_tag="ACG8LA_001818"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HFQ0204114.1"
                     /translation="MAETIVKTGQTVPLKIKRLGINGEGIGYFKRLIIFVPYALPKEE
                     VLVKITKATPRYAEGELIKVKKTSKDRVVAPCPVYYECGGCQLQHLAYQAQLDFKKDL
                     LLQALEKFKPAGFRSYQLLPTIGMDEPWHYRNKAQFQLRKNKQTQKIEAGLYEANSHQ
                     LVPITDCLVQEPRTQKVMNTVVQLLNKFDAPIYDERTNSGIFRTIMVRIGVKTGELQV
                     VFITRSKKFPQKNAMIREINERLPEVVSIMQNVQAQKTSLVMGDETIHLWGKEAIEEQ
                     INEVTFDLSPRAFFQLNPQQTELLYGEGIKALDVQPNETIVDAYCGVGTIGLSVAKQA
                     KEVRGMDTVPQAIADAKKNAERLGYHNTRYEVGTAEQVLPKWLNEGFQPDGIIVDPPR
                     TGLDNALIQSLLKYPPKKLVYISCNVSTLARDLVNLSKKFKIEYLQSVDMFPQTARCE
                     VVVKMTRLAD"
     gene            complement(9603..10181)
                     /locus_tag="ACG8LA_001819"
     CDS             complement(9603..10181)
                     /locus_tag="ACG8LA_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic polysaccharide monooxygenase"
                     /protein_id="HFQ0204115.1"
                     /translation="MKKISTLLFIGLVSLGLFGFSIPGFAHGYITSPGSRAYLGTSAA
                     GNLNQNVGRAQWEPQSIEATKNTFIDGKIASAGVSGFEPLDEQTSNRWHKNMVNPGTL
                     NITWNLTAQHRTSTWDYYITKPTWNPNQPLKFSDFELITKIDDKATVPPKTVNQTITL
                     PQDRKGYNVILAVWNISDTTNAFYQVIDVNIQ"
     gene            10503..10973
                     /locus_tag="ACG8LA_001820"
     CDS             10503..10973
                     /locus_tag="ACG8LA_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TspO/MBR family protein"
                     /protein_id="HFQ0204116.1"
                     /translation="MKMIKDIRFWVCVIGIVILGFLSGLLSGNPGKYYYSLQLPPFAP
                     PSWIFGPMWTLLYILMGISLYLLLNHNNKKQRNNLVGLFVIQFIFNFIWSALFFNLRN
                     IFIAAIDITLLVIFLSVLMYQLWLHHRLAMWLMIPYYLWVLFATLLNYSIYFLN"
     gene            complement(11081..12307)
                     /locus_tag="ACG8LA_001821"
     CDS             complement(11081..12307)
                     /locus_tag="ACG8LA_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HFQ0204117.1"
                     /translation="MKRWQKVLLTLLGVFVLLIAGLSAYGIRFMGEASQTVNKISKNS
                     NRISSKRSERVSIDDKEPFSVLLLGLDTGGLGRTEQGRSDTMMVVTVNPKQKKSTIIS
                     LDRDIYTNIVGYGTVDKLNHAYAFGGVEMAMDSIEQLLDIPIDHYVTINLDGMEDLIN
                     AVGGIKVNNKIDFTLDGVHVPVGEQTLNGEKGLAYSRMRHEDPEGDIGRQRRQREVVT
                     KIVNKVLSLDGVSNYRKILKAVENNVTTDLDWDDMLDVATNYTPAFETIKQDQLQGEG
                     QMINDIYYQILGKNDLLSIQNELKKQLNIKTSDTLPNLKNENASMMFFDDSEDGDSTN
                     GDGSNSEGYTDYSSYSENTYDQYQDPNTYYQQTEDTSQYYTPSQDTQSYDPYAGQEQN
                     GYGYDQNNEYGTTSGY"
     gene            complement(13061..13261)
                     /locus_tag="ACG8LA_001822"
     CDS             complement(13061..13261)
                     /locus_tag="ACG8LA_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003230776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HFQ0204118.1"
                     /translation="MEHGTVKWFNNEKGFGFITVDGGDDVFVHFSAIQGDGFKSLEEG
                     QEVEFTIVEGARGPQAAEVTKL"
     gene            complement(13395..14003)
                     /locus_tag="ACG8LA_001823"
     CDS             complement(13395..14003)
                     /locus_tag="ACG8LA_001823"
                     /EC_number="1.15.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004784 - superoxide dismutase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HFQ0204119.1"
                     /translation="MTYTLPDLPYAYDALEPYIDEETMHLHHDKHHNTYVTNLNSAIE
                     KYPELGEKTIEELLSDMDAIPTDIKTAVRNNGGGHANHSFFWEIMAPNAGGEPTGEIK
                     EAINEAFGDFSSFKEEFKKAAAGRFGSGWAWLVMENGKLAITSTANQDSPLMEGKTPI
                     LGLDVWEHAYYLKYKNVRPDYIAAFWNVINWDEVNKRFEAAK"
     gene            complement(14088..14558)
                     /locus_tag="ACG8LA_001824"
     CDS             complement(14088..14558)
                     /locus_tag="ACG8LA_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HFQ0204120.1"
                     /translation="MKQYRQLKGYLEAKGYWEILVYLFFGGLATIVNFVSFALARQYF
                     DLSMALSNSISWFCSVLFAFVTNKLWVFHSKSPNFTHALIECGKFFFYRILSYGLDMG
                     AMVLLINVMNSNEYVAKIITQIIVILANYIFSKLFIFKETEVFEEEVGQSEKDD"
     gene            complement(14606..15520)
                     /locus_tag="ACG8LA_001825"
     CDS             complement(14606..15520)
                     /locus_tag="ACG8LA_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HFQ0204121.1"
                     /translation="MEEGIVPTQPQRSSKKLFGVVVLNAVITLSEFIGGIMSGSLSLV
                     SDAFHNLSDTLAIIFSYGAQKMARKEANKKRTYGYQRLEILSAFINSFILIILSLFLT
                     VEAFKRFTSPEKINSHLMLTVAVIGLLANLFSVLLLRQEADESLNIKSSYLHLLSDTL
                     SSVSVIIGAILIRFFDIYWIDPVITLIISIYILIEAIMVIKKAAAILIQSAPAIDYEK
                     MEQEIEAIDGVKDVHHVHIWQYSEKIIIFDGHIDFEDQLLSEIEKIYPRIISLLKLKY
                     GITHVTIQAETKAKDQKKLIFLNKDESY"
     gene            15666..16469
                     /locus_tag="ACG8LA_001826"
     CDS             15666..16469
                     /locus_tag="ACG8LA_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HFQ0204122.1"
                     /translation="MTTKQLIISSFIRFKDLKEARNVPFWKAIVYLLVLSIIMALPIS
                     FQVFQVLNNIQLDGQKIATRIPDFTIQNGQLQTEEKEGFIYQTNSIIFTFDPEGKRTE
                     QDISTDLMGNFVSVGMLKNKLIIALPNTGTTSALLNNNQLELPYTNESLKNLTGKQLR
                     SFLSEASIPLWIKVLTFIFSIYPSFLNLLITLLFTNIAAFLYARFRLTKATFLDCLKT
                     LIYSISLPTIIATILMVFLPSFDTSAFIAFAGIFIFAQAVKGWAKISIN"
     gene            16647..17594
                     /locus_tag="ACG8LA_001827"
     CDS             16647..17594
                     /locus_tag="ACG8LA_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate dehydrogenase"
                     /protein_id="HFQ0204123.1"
                     /translation="MSERIIYADRPFRDEFIEEIHTIAPGYIFKTELQPEDLQNVEIS
                     LGWNSDYQEKLLASSTLKWVQSISAGVDQLPLETFSKKHILLSNGSGIHSESITEHVL
                     GIILGYSRGLFQAQKAQSDMKWLGSSVHYQSIQGKKILIIGTGHIGKMIAKKCKALDM
                     NCYGINTSGHPAEGMEKTFSLNQLKEVLPEVDFVVNILPLTEETTGLFDQHMFEHFDP
                     KSVFINVGRGASVKTQDLVQALNNQQLSFAALDVFEEEPLPQDHPLWKMDNVLITSHI
                     AGLTPDFQKKLMAIFLTNLKSYFATHELQTNQVKLSAGY"
     gene            complement(17662..17955)
                     /locus_tag="ACG8LA_001828"
     CDS             complement(17662..17955)
                     /locus_tag="ACG8LA_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HesB/YadR/YfhF family protein"
                     /protein_id="HFQ0204124.1"
                     /translation="MKLTVTPKAQKWFDSEIDLPETYGIRFFGKVYGKTEVHDGFSIG
                     MSVEQPEHPVKKVEIDGTLFFIEEADEWFFKGYDLLVDYDPNLEEPTYHFKKQ"
     gene            complement(17983..18648)
                     /locus_tag="ACG8LA_001829"
     CDS             complement(17983..18648)
                     /locus_tag="ACG8LA_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006813 - potassium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HFQ0204125.1"
                     /translation="MKQNFAIVGLGRFGGSICRTLIEAGQEVLAIDSNEDRVNEYMNI
                     ATHAVVANAQDEMTLRSLGIRNFDHVIVAIGEDIQASILVTLMVKEMGVPNILAKAQN
                     EYHARVLEKIGADRVVHPERDMGIRIAHNLVSKNILDYLELSDKYSLAEIRVSNPKFF
                     NKTLAELNFRQRFDLTVVAIRRVDQTVIASPAADEYVRENDNLLVIGETGDVDILDDK
                     MNQ"
     gene            complement(18788..19420)
                     /locus_tag="ACG8LA_001830"
     CDS             complement(18788..19420)
                     /locus_tag="ACG8LA_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFQ0204126.1"
                     /translation="MIKVLLVDDHEMVRLGVSFYLSIQEDIEVIGEAENGRQGYEKAM
                     TLRPDVILMDLVMEEMDGIESTKAILKDWPEAKIIIVTSFIDDEKVYPAIEAGAAGYL
                     LKTSTAHEIADAIRATQRGERVLEPEVTTKMMEKMSRRNEPVLHEELTNRENEILMLI
                     SEGKSNQEIADELFITLKTVKTHVSNILAKLEVEDRTQAAIYAFKHGLVK"
     gene            complement(19427..20494)
                     /gene="liaS"
                     /locus_tag="ACG8LA_001831"
     CDS             complement(19427..20494)
                     /gene="liaS"
                     /locus_tag="ACG8LA_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     LiaS"
                     /protein_id="HFQ0204127.1"
                     /translation="MMGKISRAMLAVYSGIAAFLIILFSLFTYFYASNQSHWWGELLR
                     ARLLYVPLIFHLLAISLGVGLIVFLLLSLIQKTKYGKIEEKLRALSSGNYESKLLLLP
                     IPSASDDLYIKDIDKEITKIKEKMIEVSSELQIVTSRPQYVDGQTKEEILELERHRLA
                     RELHDSVSQQLFAAMMMMSALTEQAEKSETPEMFRKQLKMVAEIINASQSEMRALLLH
                     LRPVNLEEKSLKQGIEQLLKELQNKIQISLKWDVEDVKLSSSIEDHLFRIVQELLSNT
                     LRHAKANELEVYLHKIDNNLLLRIIDDGTGFNMNETKTGSYGLNNIKERVAGIGGTVK
                     IISFKGQGTSVEIKVPLMKEA"
     gene            complement(20491..21222)
                     /gene="liaF"
                     /locus_tag="ACG8LA_001832"
     CDS             complement(20491..21222)
                     /gene="liaF"
                     /locus_tag="ACG8LA_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein
                     LiaF"
                     /protein_id="HFQ0204128.1"
                     /translation="MNSSWRFFVVVEALLLLFAVWQIVNNTGLLLLVIFGIFNIYLAM
                     RKHPRTKFQNFQLILGSLVIFFSLVNSPALWMMAVFAVLFIGLKGVEISGIDLTKNAF
                     WRKKQIMMIQTEQLKTHNNERKRQQLFGNQRIGNDVYEWDDINIAVISGDTIIDLGNT
                     LLPKDDNIVIVRKGIGRTRILVPLGVAIRLEHATLVGNVLFEEEQFSLKNEQIKIYSS
                     DYDENPRRLKIITNTLIGDVEVIRI"
     gene            complement(21391..21870)
                     /gene="greA"
                     /locus_tag="ACG8LA_001833"
     CDS             complement(21391..21870)
                     /gene="greA"
                     /locus_tag="ACG8LA_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HFQ0204129.1"
                     /translation="MVEKVYPMTLEGKEKLEKELEELKTVKRGEIIERIKIARGFGDL
                     SENSEYESAKDEQAFVEGRITTIENMIRFAQIIDNDGVDADEVSIGKTVTFIELPDGE
                     EEEYTIVGSAEADPFSGKISNDSPIAQALIGKRKNDEVTIATPGGDMLVKIVKVEQA"
     gene            complement(22006..23181)
                     /gene="mltG"
                     /locus_tag="ACG8LA_001834"
     CDS             complement(22006..23181)
                     /gene="mltG"
                     /locus_tag="ACG8LA_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008932 - lytic endotransglycosylase
                     activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HFQ0204130.1"
                     /translation="MSGNKQHPSKDKKEASKAATADIIDKRRNLRKKEDKIVRKIILV
                     IALTLLIIGGFLGFTVYRYVDSGLKPLDKSDDQLVQVEIPSGSSNKQIGEILEKDNII
                     KSGIVFNYYTKFKNLTGFQAGYYQLAPNMTLDEIGKQLQEGGTSEPTKVADGKIAIPE
                     GYDIDQIAERVAKVTGKDKKEFLDLVNDETFFNELHQKFPELLESASKAENTKYRLEG
                     YLFPATYDYYTSTSLKDLVIEMVNKTNTVMQNYYSAIKQKNLTVQEVLTLASLVEKEG
                     VKENDRKNIAQVFFNRIKANMPLQSDISVLYALGEHKELVTYEDTAVDSPYNLYTNTG
                     YGPGPFDNPSEEAIKAVLEPAENDYYYFVADTSTGNVYFAKTYEEHMELVEKYVNNS"
     gene            23385..24554
                     /locus_tag="ACG8LA_001835"
     CDS             23385..24554
                     /locus_tag="ACG8LA_001835"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase domain-containing protein"
                     /protein_id="HFQ0204131.1"
                     /translation="MKKGKHAKKRKYSFLMIVVVLFSLSAFSTGTILGWQFYNNEHSQ
                     IVAHAQSAQKKLILTTNEQQLVEKIDQLLRKNDYIGSIYVKKNNRIIMEKGYGYANKL
                     TQQPNDPSLYYQIGSVQKALTTLLILKQVERGHLSLDTKLAQFYPQIAGSQQITIRDL
                     LYMRSGLHRTASPTIPMTDEEVVQFAIQHLKFTDYQTSHYDSLNFTILTGILIKLTNQ
                     PYEKLLTDDIIEPLGLQHTKFYDQVKNSSNHALSYQMSKEDDYFKPLTESETEIHNEL
                     GTGNISMSVYDLNTLFTQVLSGKLVSKDLLFSLWRENANGHPYSGGVYSGDNYILSQG
                     NIDSFDTSAIFSKDSQDAIIMESNIKADKTIKLPTADLRNQIYDLMEGTTKLANS"
     gene            complement(24821..>25651)
                     /locus_tag="ACG8LA_001836"
     CDS             complement(24821..>25651)
                     /locus_tag="ACG8LA_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204132.1"
                     /translation="FLIGSIDSELLSFGIGLTLLICLIILTFNFKKLGILSKITYIMG
                     IISILLCTKIFPWFALQNTPLNIIQAPWRFMIFSTLFISFSVSLFISPQLEKFSYTRR
                     RNFILLLILAISILNYSSVVNMVKEMNFQGTYSNEQMENKLEEFENFDYVPIGYKKDQ
                     LLLKNHQVTEDGQVIYSSFSPNKDEITFTFKSSKGKTIVLPVFRYKGLTVTVNSKNAT
                     VLKQGGPFVTVKSESGINKVTIRYSYTFFSKISLFISIITLIVLLFYCIKLKIRTSHE
                     "
BASE COUNT         7810 a         5108 c         4116 g         8617 t
ORIGIN      
        1 cgtcacggct ctaaacaaaa tatgagaggc tgtttttgtt tggctattct tattacttga
       61 tgcagggcag cttgtgtcaa gacttcttta catcaaactt tttaatttta cattgggata
      121 tttatccgca aaccagcgtt ctgcaaattg gttctcgaat aagaacaacg gttggtcgaa
      181 acggtcacga gccaagatat tgcgacttga actcatcttc tcatccaaat cttctggatc
      241 gatccagcga gcgattttgt gtcccattgg agacatgatt acttcggcgt tatactcatt
      301 taacatacga tattggaata cttcgaattg tagctgacca acagctccaa tgatatattc
      361 ttccgttaga tatgttttat aaagctgaat cgctccttct tgaactaatt gatagattcc
      421 tttgtggaag gatttttgtt tcatgacatt ttttgcagtc actttcataa acagctctgg
      481 agtaaatgaa gggagttctt cataagcaac ttttagtttt ccttcgaaca atgtatcccc
      541 aatctgataa ttgcctgtat catatacacc gatgatatcg cctgctactg ctttttcgac
      601 gttttctctc gaatctgcca taaattgtgt gacattgctt aatttcagtt ttttatttgt
      661 acgttccaac cagacatcca ttcctcgttc gaatgttcca gaacagattc ggacaaaagc
      721 gattcggtca cgatgggctg gattcatatt tgcttggatc ttgaatacga aacctgaaaa
      781 ttcttcctca taaggactta ccatctgatc atcttgtgtt ttgtgtccat aaggagctgg
      841 tgccaattca acgaaagtct ctaaaaaagt ctgtacaccg aagttagtca atgcagaacc
      901 aaaaaatact ggtgtctgat cgccacgagc aattttttct tgattaaatg catctccagc
      961 ctctttgatt agttctactt cttctaagac ttgttcatat aaggaatttt cagttagagg
     1021 atgattttcg ggaagcagtc catcttcatc caattctact aatcgttcat cctgataatt
     1081 ttccggacga taaaactcta cacgattatg gtagatatca taaagacctt ctagcccttt
     1141 acccataccg attggccaat tcatcggata agattcgata tctaatagct cttctaattc
     1201 ttctaacaat tccaatggtt cacgaccatc acgatctagt ttgttgataa aagtaaatat
     1261 cgggatgcca cgttttttta caacttggaa taatttcttt gtctgtgctt cgatcccttt
     1321 tgcactatcg attaccatga ccgcactatc cacggccatc aaagtacgat aagtatcttc
     1381 agaaaaatct tcatgtcctg gtgtatccaa gatatttact cgtttccctt gataatcaaa
     1441 ctgcataaca gaactagtaa cagaaatccc acgttgtttc tcgatttcca tccagtctga
     1501 tttggcaaaa ttacctgttt ttttgccttt tacggtcccg gcttgacgga tagccccacc
     1561 aaacaatagt aattgttctg taatcgttgt tttcccagca tccggatggg aaatgatcgc
     1621 aaaagttctg cgattgtcca cttgttgctt taattttgga ttattcataa cctaactcca
     1681 tttcttccat tcaattattt atattttctc taggcacaga ttgtccgatc tcttaaagaa
     1741 agacaatttc atatagggct gtgacaaaag ccgtgtagca gtctcttttt ccgagtaaac
     1801 ggcgttctag agacagccta tcagcaataa gcccacccaa gccaaaaata cgaaaagctg
     1861 tttttgcttg gctgctctta ttacttaatg caggatagct ttttcacaac ctttgtcaac
     1921 tactacaact gaatcagtat agcatggatt cagcgaatga aaaagccacc aaaccataag
     1981 agtcaaatat ttttttgtca gctgactaaa agaaaagacg tgttgcttgt ttattcaagc
     2041 aacacgtctt tcataaccaa gtttccaatt atcttcttgg ctcgtcatct tcgaattctt
     2101 ttctgaagta tcttcgttct tcttcaggtt ccgcttctgt ttcttccgga tcatgaaaaa
     2161 tgacacggat tttaaggatt cgagaacctt ccatttcttc agaaaccagc gtaatattat
     2221 cgacatcaaa cgataacttt tcgccttcat ccggaatcat gcctaatgct gtaatcaaat
     2281 aaccagccat cgtatctaca tcactcatat gcagatcact gtcaaaagct tcattgaact
     2341 catcaatcag catacgtcct tggatgatat attcgtgttc atcgattttt tcataaagat
     2401 tctcaacttc atctgattca tcatcgattt ctccgacgat ttcttctaaa aggtcttcta
     2461 gtgttgctaa cccaacgacg ccgccatatt catctaataa aatagccatc tgattctgcg
     2521 tctttttcat ttcatataac agatcatcaa taaagaccgt ttcaggaacg aataaaggct
     2581 cctgcatgat tttcttgata tctaaattat caaagccgaa tttatgggca gcttttagta
     2641 aattctttgt atgaaggatt ccgactactt tatctttgtc ttcgttataa acagggattc
     2701 ttgaatagtt ttcggataaa acttcattca cattttcttc cacagtgtcg ttgatatcaa
     2761 tcataaatgc atccgttcgt gggaccatga cttctcgggc aactttcgta tcaagagaaa
     2821 aaaccccttg gagcatttct aattcttcat tattcaatac gccttcgttt tcaagcatat
     2881 aacgcatttc atctctggtc atttttgaat cttcatcatc aaaagtcatc ggcgtgatac
     2941 gcgccaataa acttgtggaa gcagaaagca gccagacgaa gggcttagct actacaccaa
     3001 tcaagcgtat cagccctgaa gtgaactttg cgacttcttc tgatttattt aaagcaatac
     3061 gtttagggta caattctcca aaaacaatcg atacataggt caaaatagcc agcacaatga
     3121 tatttgcaat attttttgcc gctgtgccgc cacctaatac cggagctaac cgttccgata
     3181 aagtattagc tagtgaagca ccagacaaaa tgttgaccaa agtgattcct acttggattg
     3241 tcgataggaa attatttgga ttctgcaata tttttaaaag cttttgagat ttcacatctc
     3301 cttcatcagc tttttgctcg attcgattct tattgatcga aacaacagca atttcggaag
     3361 ctgctaaaaa agcattgatc aatgtcaaaa cgatcaataa taaaatctgc gctaacagcg
     3421 actgactctc agggtcagca ttcataatcg cattctctcc ttataaaatt aatttttagt
     3481 ttacgataga aaaaaacgtg gcactatagc cacgttaaaa tggtatcaca aagcaatttt
     3541 ctttgcaata aaaacaagtg tactaaaact acctacgagg tcgtagcaat tttcttcttg
     3601 ttttcatttt gcttgtcttc tttgacgatt ttgattatat aggaaatgat cgtcttgcag
     3661 attgcgtaaa aaggaacacc taagaagata ccaagcaatc cggcaatatt tccagctact
     3721 agaagaacga taatgatcgt taatggatgg attttcagtg atttcccaat tacattagga
     3781 taaatgatat tcccatccaa ctgttggacg attagcacaa ccacacaaca aagtaatgct
     3841 tttaccggat cattgaagac tgttactaga aatgcaggtg ctagtcctag ataaggtcct
     3901 aaatatggaa ttaggtttgt caatcccgca atgaccccaa ataagaaagc ataatccaca
     3961 ccaattacca tatatcctaa aaatgtgaag gtaccaacga ataaacattc gattgcttgt
     4021 ccgctaatgt aattagccaa tgttttattc agttgcccca ataactccac aatttggttt
     4081 cttctttttt ctgggaaaaa ctgttggatg tttggcacta gtttttctcc gtctttcaac
     4141 atatagaaca agatgaatgg tgctgtaatg attactacgg ttgccgaagc gatcgttcca
     4201 acgatcgaac ctaaactatt ggatactcca ctaaggaatt gctgaatgat tgtcccgtaa
     4261 gaaatgtcta attgctcaaa atatttattg atatctactt ccttgaacaa aggcaattcg
     4321 gctacctctt ttaaccagct ttctacctgt ttgatgaaat caggcatatt agatgccaat
     4381 gaggaaattt gctgtactag acttgggatg acactaagta aaatccaaat aattgctgca
     4441 actaaaagga gcagcacaat tgcgacagcc catattcttt tgatttttgc tttcatcaac
     4501 agcttgacaa taggattcaa taaatagtaa agaaagcctg caatcagtac aggtgcaaat
     4561 aacgtggaaa aaaatgtccc gatcggttcg aaaataaagt ttatttctga tgaaatcatg
     4621 atcaatgcag ctatgatcaa taattcaagc gaccaaaaca ttagtttaga ctgtctaagt
     4681 ttttcaaaca atagatttcc tcctttcttt cttactagta tatattatat tcgttaaaaa
     4741 ttcttttatt ctttttttat ttttgaaaac ttgccatact ttttatttgt tttattttcc
     4801 agtatactat acgaaaggaa ggtggctaga ccatgaaagt tgtacaaaca aaagatacaa
     4861 tgagcaatat ttacttagat gctgtacgga tcaggcatca agtttttgta gtcgaacagg
     4921 gtgtgccttt gtctcgagaa atagacaaag atgaagccca ttgtatccac ttcgtcctgt
     4981 actcagataa aaaagaaccg caaggaactg tacgtctttt gcctttagaa aacggaaaaa
     5041 tgaaattaca gcggatggcg attctttctg aatacagaca ccaagggtta ggaaaaatat
     5101 tgattgaaga agcagaaaac tttgctaaga atcaaggcta taatacgatt ttattagggg
     5161 cacagtccac agctgaaact ttttacgaaa aactaggata tacagcttac ggcgatcctt
     5221 ttgaagatgc tggcatgcct catatttata tgaaaaagac tttataaaaa tttatttcga
     5281 aaaaagcaaa aaacagcaag cttttgagaa aaatctctca ctggcttact gttctttttt
     5341 gtgtttactt acgcgacaat tgcttgtaac ggttatacca aatatcaata tagccttccg
     5401 agaacgggcc atctccatta ttgatccagt caaccagaat cttcacattt tcttttagga
     5461 tgaagtcaat atcgttcggg taattcatca ttttgctgtg catctcatat tcatcgacat
     5521 ccaatagtcg tttctcgccg tcaggaaata ccttgatatc caagtcatag tcgatatatt
     5581 tcaaggcctc atcgtccagc aaaaaaggtg aagctagatt acaataatag gaaaccccct
     5641 tttctctgat cattgctatt acattgaacc agtatttttt atgaaaataa acaatcgctg
     5701 gttcgcgcgt tacccatcgg cgtccatcag attcagtgac taatgtgtga tcattcacgc
     5761 cgatcataga gtgttcgctt gtttttaata ccatggtatc tcgccacgtt cgatgcaatt
     5821 tgccgtcgtg cttgtaactt tggatcgtca caaactctcc ttcttttgga actcccatag
     5881 caacccttcc ttaagcagca ttttgtgctt tgtgtttggg tgttcattac accgacatca
     5941 taattattat atcaataaaa atgagctttg cctagaaagg attcctattg tttcgatttt
     6001 tctctaactg atctaccagt ttcatttgga ccttaggaaa aacgaccgaa tcaaatgcat
     6061 caggcttcaa ccacttcgaa gttttgttct cggtaaattc ttgttctgct ccctcggttg
     6121 cccgtccgta aaaaaggaga acatgccatt tcagatgact aaaaatatga gtaacttctc
     6181 ctaaatgtcg tgtctgccaa acaaagagtt cctgcttttc aaatgggaga ttttgctctt
     6241 cttctgctac taggtcatca aacagatcga tttctggctt tgtttcccat tcttttttca
     6301 atcgctcata ctcctcttgt gtcacttcca tcattggaaa tgtccacata ttcgccagca
     6361 atttttggct atctctttct tcaaaataat acgctccaga atgattttga agagctgcac
     6421 tgatataata aacgtctttt ggctttgctt tttttgtttt tacaggaaaa ctcgtttgga
     6481 ttcctcgttt gttagctaaa caaaaggctt ggatcggaca agtctcacac tttggagaag
     6541 ttggtgtaca gatagctgaa cctagatcca tcattgcttg gttgaattca cctggatgct
     6601 tttcatcaat gattttccgc atcgcttcat caaagatttt cctgctagaa gcttttgcga
     6661 tgtctgcttc aatgcaaaac aatctgctga ctactcgcat cacgttgccg tcaactgcag
     6721 gttctggaag tccaaatgcg atacttgcaa tcgcgcctgt cgtatatggt cctattccct
     6781 tcaatgagct aatttcttca ggcgtttgcg gcatttcccc atcaaattct gacatgatct
     6841 gtttagcagc agcttggatg ttccgggctc ttgagtaata accaaggccc tcccatgctt
     6901 ttaaaagctt ttcttctgga gcatttgcta gctcttcaat tgtaggaaac cattccatga
     6961 aacgataaaa ataatcgatc actgtgtcta ctctggtttg ctgaagcatg atctcagaga
     7021 tccagatacg ataaggatca cgattatagc gccaaggcag gtttcttttt tcttgttcat
     7081 accattgaat gaactgatct tgaaattctt ttgtttcttt atctgtccat ttttcccatt
     7141 ctttattcac tttcctcttc cttttccgta atgaatcgct ggatcatatc caaatcaaat
     7201 cctttttgat ataagctttg ctttactttt agatttcttt ttttaggttc aaaccttaaa
     7261 tttcttcgcc atagtttatc tccttgtttg actaaataat catattctat ttcttgatct
     7321 gcttcttgcg gaagatcagc tatcgcttgt tggatcactt cttgagaaaa gcctttcgtc
     7381 atcaatgttt gttggatttt tctcaataat tctttttggc tttttccgtg attttttcca
     7441 aacgcttttt cggctgtctg atgtgcattt tgaacttggt cttcaaatgt atattggctg
     7501 agcgcttgtt caatgatttc aggtttcaaa cctttttgct gcatctgctg cgctaatttc
     7561 tttggtcctt tgtcacttaa gcgcatattc gtgcgcacat aactttcccc atagaccaaa
     7621 tcatcgacaa ggtccaattc ttttaagcgg gctacgattt tatttcgatc ttcttgaagg
     7681 atttcctttt cttttaagta tgttcggatt tctttttccg atcgcaactg ataacttaag
     7741 taattcattg ctaggtgaaa accgaaatca gctccgctac tcttcttgat ctcttggata
     7801 gtttcttcgt ctaattcccg tccttttaat aatcgatagc gtactaatac atcttcagat
     7861 acttgtaaag cttctccttc agataaatct acgcgataga aagggccttt gcctttactg
     7921 attctcgtaa cggttaacat aaacatcctc ctcgaacata tattctctat cataccacag
     7981 aaaatccccg taatcaggta ttatatgtta gaataaacca cagaaaaaag aaaaagggag
     8041 atacttatgg cagaaacaat tgtcaaaact ggacaaacgg ttcctttgaa aatcaagcgt
     8101 ttaggcataa atggtgaagg aatcggttat ttcaaacggt tgatcatatt tgttccatat
     8161 gcactaccaa aagaagaagt actagtgaaa atcacgaaag caactcctcg ctatgcagaa
     8221 ggagaattaa taaaagtcaa aaaaacaagc aaagatcgcg tagtggcacc atgtcctgtt
     8281 tactatgaat gcggtggctg tcaattacaa cacttagctt atcaagctca attggatttt
     8341 aaaaaggatc tgcttttgca agcattggaa aaattcaaac cagcaggctt tcgatcttat
     8401 caacttttgc cgacgatcgg gatggatgag ccttggcatt atagaaacaa agcacaattt
     8461 cagttacgaa aaaataagca gactcaaaaa attgaagctg gtttatacga agcaaactct
     8521 catcagttag tccctataac agactgcttg gttcaagaac ctcgaacaca aaaagtaatg
     8581 aatactgttg ttcaactatt gaataaattt gatgcaccca tctatgatga acggacaaac
     8641 agtggaatct tccgcacaat catggttaga atcggtgtta aaactgggga gttacaagtt
     8701 gtttttatta ctcgcagtaa aaaattcccg caaaaaaacg caatgatccg tgagatcaat
     8761 gaacgactgc ccgaagttgt ttcaatcatg caaaatgtcc aggcacaaaa aacgtctctc
     8821 gtgatggggg atgaaacgat ccacttatgg ggaaaagaag ccattgaaga acaaatcaat
     8881 gaagtgactt tcgatctttc tcctcgtgcc ttctttcaac tcaatcctca gcagaccgaa
     8941 ttgctttatg gcgaaggaat caaagcatta gatgtccagc ctaatgaaac gatcgtggat
     9001 gcttattgcg gagttgggac gatcggctta agtgtagcaa aacaagccaa agaagtacgg
     9061 ggaatggata ccgttcctca agcaatcgct gatgcaaaaa aaaatgcgga aagattagga
     9121 tatcacaaca ctcgatatga agtcgggaca gcagagcaag ttctgcctaa atggttgaat
     9181 gaaggttttc agcctgatgg tatcatcgta gatccaccac gtacgggttt ggataacgca
     9241 ttgatccaat cattattgaa ataccctcca aaaaaacttg tttatatctc ctgtaatgtt
     9301 tctacacttg ccagagatct ggttaattta agtaaaaagt tcaagattga atatttacag
     9361 tccgtcgaca tgtttcctca gactgcacgt tgtgaagttg tcgtgaagat gacgagactc
     9421 gctgactaaa tgaaagaggt tgtgaaaaag tctgccctgt atcaagtaat aagaacagcc
     9481 aaacaaaaat agctcttcat gttttatgaa tactgtactt gtgaccgaag agttaacagg
     9541 aggacactat ttatttaaaa aaagggttgt gacatagttt ttgtcacagc cctttttgat
     9601 tattattgga tattcacgtc tatcacttga taaaatgcat ttgtcgtatc gctgatattc
     9661 catactgcta aaatcacatt atatcctttt cgatcctgcg gaagtgtgat cgtttggttg
     9721 actgtttttg gtggaacagt tgctttgtcg tctatttttg tgatcaattc aaaatcacta
     9781 aatttcaaag gttgattagg attccaagtt ggtttggtaa tgtagtaatc ccaagtactt
     9841 gtccgatgtt gtgctgttaa attccaagta atatttaatg ttcctggatt aaccatgttt
     9901 ttatgccatc tgttagatgt ctgttcatct aaaggctcaa agccgctgac tcctgcacta
     9961 gcaatttttc catcaatgaa tgtatttttg gtagcttcga tactttgcgg ttcccattgt
    10021 gctcttccga cattttgatt taagtttcct gctgctgatg ttcctaggta tgcacggctt
    10081 cctggagaag taatataacc atgcgcaaaa cctggaatgc taaaaccgaa caaccctaaa
    10141 ctaactaacc caataaacaa taacgtacta atctttttca tgtagaaacc tccttcattt
    10201 gataaccaca ttgtaaacgc tttattgtat taacacaaac attatgcttt tataatttta
    10261 tgttgaagta aaaaaggtga aaaaagtaag atgcagatta taacagaagt agacgagaaa
    10321 agtacaaata gaaaacatga gaatcaaatc atatgatctt tttcaaaaac atcattcata
    10381 taaacaaatg ttcaactttt taataacaac aattatcaat ttttttctta cttcacaaac
    10441 taaatacagg tcttgctgtg agccttcatg gtaaactaat attatagaaa ggagttagta
    10501 aaatgaagat gataaaagat attcgttttt gggtttgtgt tataggaatt gtcatattag
    10561 gctttttatc agggttgctt agcggaaatc ccggaaaata ttactattct ttgcaacttc
    10621 caccatttgc accacctagc tggatatttg ggccgatgtg gaccttactg tatatattga
    10681 tgggtatttc tctttatttg ttacttaatc acaacaacaa aaaacagcga aacaatcttg
    10741 tcggtctttt tgtgattcag ttcattttta attttatatg gtctgctcta ttttttaatt
    10801 taagaaatat tttcattgca gcaatcgata ttacactttt agttattttc ttgtcagtgc
    10861 ttatgtatca gttgtggctg catcatcgcc tggcaatgtg gctcatgatt ccttattatt
    10921 tatgggtact attcgcaact ctattgaatt attcaattta ttttttaaac taagcgctaa
    10981 aaagagacgt cctgtaattt aacacataga aaaagtgcca cctaagttag attttttgtc
    11041 taatttaggt ggcactcttt attaaccaaa ctattttttt ctagtaccca cttgttgttc
    11101 catactcatt attctggtca taaccataac cattttgttc ctgtccagcg taaggatcat
    11161 aactttgagt atcttgactt ggtgtatagt actgacttgt atcttctgtt tgctgataat
    11221 aggtattcgg atcttggtac tgatcatatg tgttttctga ataggaagaa taatcggtgt
    11281 acccttcact attcgatcca tcaccgtttg tcgaatcgcc atcttccgaa tcatcaaaga
    11341 acatcattga agcattctca tttttcaaat taggtaatgt atcgcttgtt tttatattta
    11401 attgtttctt cagttcattt tggatcgaaa gaagatcatt ttttcctaaa atttgatagt
    11461 agatatcatt gatcatttgt ccttcgcctt gcaactggtc ttgtttgatt gtttcaaacg
    11521 ccggggtgta gttcgtcgct acatcaagca tgtcatccca atctaagtcc gtcgtcacat
    11581 tgttctcaac tgcttttaaa atttttctat aattgcttac gccatctaaa cttaaaactt
    11641 tattgacgat tttcgtcact acttcccgct gacgacgttg tcgaccgata tcgccttctg
    11701 gatcttcgtg tcgcattcga gaataggcta aacctttttc tccattcaat gtttgttcac
    11761 ctactggtac atggacacca tccaaagtaa agtcaatttt attattcact ttgatgccac
    11821 cgaccgcatt gatcaaatct tccatgccat ccaaattgat cgttacataa tgatcaatag
    11881 gaatatcgag cagttgctca attgaatcca tggccatttc gacaccacca aatgcgtagg
    11941 catgatttaa tttatctacc gttccataac ctacgatatt cgtataaata tctcggtcca
    12001 aactgatgat cgttgatttt ttttgtttcg gattaactgt tactaccatc atcgtatcag
    12061 aacgtccttg ttccgttctt cctaatccac cggtatctaa acctaatagc aaaaccgaaa
    12121 aaggttcttt gtcatcaatg cttactctct cagaacgttt ggaggatatt cgattagagt
    12181 ttttagaaat tttgtttact gtttggctcg cttctcccat aaatctgatt ccgtatgctg
    12241 ataatccggc aatcagcaaa acgaataccc ctaacaaggt taatagaact ttttgccatc
    12301 gcttcataat acacctctgt ttcacatttt ctaaaatatt gtctcatata actgttcaat
    12361 cagcaaattc actttttaat cataagaaaa ctttaaaaaa catttttgtg taacgattat
    12421 tattttttaa aatttctcaa aattcttaac tatcatacca taccgtgaaa aagatcgaaa
    12481 gaccgaatac acgcagttcg caatcgtttt atcttttttt atgtattttt tccagaaaaa
    12541 gcgaacaaca aggtattttc caaataatcg tgcagtaaaa tgatcgcaca tacctttccc
    12601 atctttttaa cagtctttgc ctaccgttca gattatcatt cgatttcacg acaatttctt
    12661 cctatgactg gtccttttgt taaacccatc ttctattcgt tttatttcca gctcactgca
    12721 tggctcttaa aatgactcga actagtgatt gcattaccat catcttttaa tggatagata
    12781 tgctcctctt caaagtaaaa cgattttctt ttaaagtaat agaattgaca tggtaatgag
    12841 tatgtatact agtggtttca caaatggtct tttattcaac atccaaaaac tgaaatttct
    12901 ttaaaatcca ttactaacga agaaaatgtt ccttgcttga taattagtta ggacatgtca
    12961 agtgaacaaa tgcatttact tagccaaaaa atctaaaaac ttcataaata gacaaaaaga
    13021 cacgactctc taagaagtcg tgtctttatt caacaaatta ttataattta gtcacttcag
    13081 cagcttgagg tccgcgtgca ccttcaacaa tcgtgaattc tacttcttga ccttcttcta
    13141 ggctcttgaa gccgtctcct tgaattgctg agaaatgaac aaatacgtca tctccgccgt
    13201 ctactgtaat aaacccaaat cctttttcat tgttgaacca tttaaccgtt ccgtgttcca
    13261 taaatgtata tcctccaaaa aagttcttgc aagtaacctt gcaagaacat tatacccaat
    13321 ttagaaaacg ctagcaagct ttcgctcttt tattttccaa attattttta agactgatat
    13381 gacggaggaa atggttattt tgctgcttcg aaacgtttgt ttacttcatc ccaattaata
    13441 acattccaga atgctgcaat ataatctggt cggacatttt tatatttcaa ataataagca
    13501 tgttcccaaa cgtccaaacc tagaattggt gtctttcctt ccatcaatgg agaatcttga
    13561 tttgcagtag aggtaatagc taattttcca ttttccatta caagccaagc ccatccagaa
    13621 ccaaatcgtc cagcggctgc ttttttgaat tcttctttaa aagaagaaaa atcaccaaaa
    13681 gcttcattaa tcgcttcttt tatttctcct gtaggttcgc caccagcatt tggtgccatg
    13741 atttcccaga aaaatgaatg gttagcatgt ccgccaccat tgttacgtac agctgtcttg
    13801 atatctgttg gaatagcgtc catatcagat aataattctt ctattgtttt ttcgcctaat
    13861 tctgggtatt tctcaattgc tgaatttaaa ttcgtcacat aagtattgtg atgcttatca
    13921 tgatgcagat gcatcgtttc ttcgtcaata taaggttcca atgcgtcata tgcataaggt
    13981 agatctggta atgtgtaagt cataaaaaaa ttcctcctca atgttttctt aataatgtct
    14041 acattacaaa gagtaacaaa gagaaggaaa ttcttcaatt gttatgccta gtcgtctttt
    14101 tcactttgac ctacttcttc ttcaaaaacc tcagtttctt taaaaataaa caacttgctg
    14161 aaaatatagt tcgcaaggat aacaataatt tgagtgatga ttttcgccac atactcattg
    14221 ctgttcataa cattgatcaa caataccatt gcccccatgt ccaatccgta agaaaggata
    14281 cggtagaaga agaacttacc gcattcaata agtgcatgtg taaaattcgg tgattttgaa
    14341 tggaataccc aaagtttgtt cgttacaaaa gcaaacaata cagaacaaaa ccacgaaata
    14401 gaattggata aggccatact taaatcaaaa tattggcgtg cgagagcaaa actaacaaaa
    14461 tttacaatcg tagccaaacc accaaaaaag agatagacta gtatctccca atatcctttt
    14521 gcttctaaat atccttttaa ctgtcgatac tgcttcatga gccaacctac cttattaaaa
    14581 attcttattt atcatactct atatttcaat aactttcatc tttatttaaa aaaattaatt
    14641 ttttttgatc ctttgccttt gtctctgctt ggatcgtcac atgtgtaata ccatatttta
    14701 attttaataa agaaattata cgaggatata tcttttcaat ctcgcttagt agctgatctt
    14761 caaaatcaat atgtccgtcg aaaataatta tcttttcgct atactgccaa atatggacat
    14821 gatgaacatc ctttacccca tcgattgctt caatttcttg ttccattttt tcatagtcga
    14881 tagcaggtgc actttgtatc aaaatagcgg cagctttttt gatcaccatt atcgcttcta
    14941 tcaatatata tatcgaaatg atcagtgtaa taactggatc gatccagtag atatcgaaaa
    15001 aacggatcaa aattgctccg ataatcacac ttaccgaaga cagtgtatca cttaacaaat
    15061 gcaaataact agattttata ttcaaacttt catctgcttc ttgtcgtaat aataatactg
    15121 agaacaaatt cgcgagcaat ccaataactg ctactgttag catcaaatga ctatttatct
    15181 tttctggtga agtgaaccgc ttgaatgctt caacggttaa aaacaaggat aatatgatca
    15241 atatgaatga gttgatgaaa gcactcaata tttctaaacg ctggtagcca tacgtacgtt
    15301 ttttatttgc ttcttttcgg gccatttttt gtgccccgta agaaaaaata attgccaatg
    15361 tatcactaag gttatggaaa gcatctgaaa caagagacaa actccctgac ataatccctc
    15421 caataaattc tgataaagtg atcaccgcat tcaaaaccac tactccaaat agtttttttg
    15481 atgatctctg tggctgtgta ggcactattc cttcctccat tttatttata ttggatagtc
    15541 tttagacaag aataacattt ttttgatatt tcaccaatca ttcagctgtt tccttaaagc
    15601 acttgtattt cacttgatac ttcgctagaa ttgcaagtga tgacactact agatgaggag
    15661 tacttatgac aacaaaacaa ttaattatca gttcctttat acgattcaaa gacctaaagg
    15721 aggcgagaaa tgtcccattt tggaaagcca ttgtctatct tttagttttg agtataatta
    15781 tggctttgcc aatctctttt caagtttttc aagtcttaaa caacattcaa ttggatgggc
    15841 aaaagattgc tactcgcatt cctgatttta caatccaaaa cgggcagctt caaaccgaag
    15901 aaaaagaagg attcatttac caaacaaact ccattatctt cacatttgat ccagagggaa
    15961 aacgaacaga acaggacatc tctactgatt tgatggggaa ttttgttagt gtcgggatgt
    16021 taaaaaacaa acttatcata gctcttccta atacaggcac gacttctgct ttgttgaaca
    16081 ataaccaatt agaacttccc tacaccaatg aatctttaaa aaacttaaca ggtaagcagc
    16141 tccgttcttt tttaagtgaa gcatctatac cactttggat aaaagtcctg acatttatat
    16201 tttctattta tcctagtttt ctgaatctgc tgatcacttt gctatttacc aacattgctg
    16261 cttttctcta tgcacgcttt cgactaacaa aagctacttt tcttgattgt ttaaaaacat
    16321 tgatctattc aatttcattg cctactataa ttgcaacaat cttgatggtc tttcttcctt
    16381 cttttgacac tagcgccttc attgcttttg caggaatctt tatttttgct caagctgtca
    16441 aaggatgggc aaaaatatcg atcaattaag aaataaagac aactcgttat ttctacttca
    16501 atagaccctt ttagaggttg tgacattttt ttgtcacagc ccctttttta tttgaaaaat
    16561 atttctttct caaaaaacaa gcaaggcgct tcaaagttct tcttgtatgc gctacactta
    16621 gagtaaagaa aggcgggaaa ttaactatgt cagaaagaat catttatgca gatcgtccat
    16681 ttcgtgatga atttatcgaa gaaatccata ctatagcgcc tggttatatc tttaaaacag
    16741 aattacaacc agaggatcta caaaatgtag agatcagttt gggctggaac tcagactacc
    16801 aagaaaaact attagcctct tctaccttga aatgggtcca atctatctca gctggtgttg
    16861 atcagctacc ccttgagact ttttcaaaga aacatatttt actttcaaat ggtagtggca
    16921 tccacagtga atcgattacg gagcatgtct taggaatcat ccttgggtat tctcgtggtc
    16981 tttttcaagc acaaaaggca cagagtgaca tgaaatggtt aggttcatcg gtccattacc
    17041 aatctatcca agggaaaaaa atactaatca ttggaactgg ccatattgga aaaatgattg
    17101 caaaaaaatg caaagcatta gacatgaact gctatggaat caatacatcc ggtcatccag
    17161 cagaaggaat ggaaaagact ttttctttaa atcaactaaa ggaagttctt cctgaagtag
    17221 atttcgtagt caatatctta cctctaacgg aggaaacaac tgggctcttt gatcagcata
    17281 tgtttgaaca ctttgatcca aaatctgtat tcatcaatgt tggccgtggt gcttctgtta
    17341 agacacaaga tctggtgcag gctttaaata accagcaact ttcctttgca gcattagacg
    17401 tttttgagga agagcctctt ccacaagatc atcctctttg gaaaatggac aatgtactga
    17461 ttacttccca cattgcaggt ttgacacctg attttcaaaa gaaattaatg gctatttttt
    17521 taaccaatct gaaaagctac tttgccaccc atgagcttca aaccaatcaa gtaaaattgt
    17581 ctgcaggata ttaatagctg aaaacaatat tttcaaaaga aaaaagagaa ggtgacaaaa
    17641 attgtgtcac cctctctttt tttattgttt tttaaagtga taggttggct cctccaggtt
    17701 gggatcataa tcaacaagta aatcatatcc tttaaagaac cattcatctg cttcctcgat
    17761 aaaaaaaagt gtcccatcaa tttccacttt ctttacagga tgttctggct gttcaactga
    17821 cattccaatc gaaaaaccat catgaacctc tgttttgccg tagacttttc caaaaaaacg
    17881 tattccgtaa gtttctggca gatcaatttc tgagtcaaac cacttttgtg cttttggcgt
    17941 taccgttaat ttcatcccaa caacctactt tctcttttct ttctattgat tcatcttatc
    18001 gtctagaata tccacatcgc ctgtctctcc aataaccagt agattatcat tttcacgaac
    18061 atattcatct gctgcaggag aagcgataac cgtttgatct actcttcgta tggcgactac
    18121 tgttaagtca aaacgttgcc tgaaatttaa ttcagctaat gttttgttga aaaatttagg
    18181 attggagact cggatttctg ctaaagaata tttatctgac aactctaggt aatctaaaat
    18241 attctttgac actaaattat gcgcaatcct tattcccatg tctcgctcgg gatggacgac
    18301 gcgatcagct ccgatctttt caagtactct ggcatgatac tcattttggg cttttgctaa
    18361 aatatttggt acgcccattt cctttaccat cagagtaact aagatactgg cttgaatatc
    18421 ttctccaata gcgacaatta catgatcgaa atttcttatg cctaatgatc gaagtgtcat
    18481 ttcatcctgt gcatttgcca caacagcatg agtggctata ttcatatatt cattgacccg
    18541 atcttcatta ctatcaatag ccagtacttc ttgaccagct tcgatcagtg ttcggcagat
    18601 acttccgcca aatcgtccaa gacctacaat tgcaaaattt tgtttcaccg ttttcctcct
    18661 ttagtatctt cttttctcag tataacaaag cctttacaaa aacaaaagca agcatcatta
    18721 ttgtaaaaaa gccaagaaaa ataatagtta ttttctcagc ttttgattat cctctttatc
    18781 atcgttttta tttcaccaaa ccatgtttga atgcatagat agcggcttgt gtacggtctt
    18841 ccacttctag cttagccaat atattggaaa catgtgtttt tactgttttc agtgtaataa
    18901 acaattcgtc cgctatttcc tgattacttt ttccttcaga aatcagcatt aaaatttcat
    18961 tttcccgatt cgttagttct tcatgtaata caggctcatt tcgccgactc attttttcca
    19021 tcatttttgt tgtcacttct ggttctaata ctcgctcgcc acgttgcgtt gcccttatag
    19081 catcagcaat ttcatgtgcg gtagaggtct tcaacaaata ccctgctgca cctgcttcaa
    19141 tggcaggata aactttttcg tcatcaataa aactggttac gataatgatt ttagcttctg
    19201 gccaatcttt taagattgct tttgttgatt cgataccatc catttcttcc atgactaagt
    19261 ccattaaaat gacgtccggt cgaagtgtca tcgccttctc atagccttgt cgtccatttt
    19321 cagcttctcc aattacttca atgtcttctt gaatagataa ataaaaagag acgcctaagc
    19381 gcaccatttc atggtcatct actaataaaa cttttatcat ccttatctat gcctccttca
    19441 tcaaagggac cttgatttct acacttgtac cttgaccttt aaaactaatg atttttactg
    19501 ttccaccaat accagctact cgttctttga tattgttcaa tccataactt cccgttttcg
    19561 tttcattcat attaaaccct gttccgtcgt caataatacg taacaaaaga ttattgtcta
    19621 ttttgtgcaa atatacctct aattcattgg ctttagcatg tcttaatgta tttgataaca
    19681 attcttgaac gattcggaac aagtgatcct caatggaact agatagtttt acatcttcta
    19741 catcccattt cagcgaaatc tggattttat tttgcaattc cttcaataac tgttcgatac
    19801 cttgctttaa acttttctct tctaaattga ctggacgtag atgaagaagc agcgcacgca
    19861 tctcagactg ggaagcgttg atgatctctg ctaccatttt caactgcttg cgaaacattt
    19921 ctggtgtctc gcttttttct gcttgctccg tcaatgccga catcatcatc attgctgcaa
    19981 acaattgttg cgaaactgaa tcatgcagct cacgggctaa tcgatgtctt tctaattcta
    20041 aaatttcttc tttggtttgt ccatctacat attggggacg gctcgttaca atttgtaatt
    20101 cactagatac ttcaatcatt ttttctttta tcttagtgat ttccttatca atatctttga
    20161 tgtataaatc gtccgatgca cttgggatcg gaagaagcaa caatttggat tcataattgc
    20221 cagaagaaag tgcacgcagc ttttcttcga ttttcccgta ttttgtcttt tgaataagtg
    20281 ataataatag aaagacaatt aatcctacac ctaaggaaat ggctaacaaa tggaagataa
    20341 gcggaacata taataaacgt gcacgcagta attctcccca ccaatgactt tgattgctgg
    20401 cataaaaata agtgaaaagt gaaaatagaa taataaggaa agccgcaatc cccgaataaa
    20461 cagctagcat cgctctggat atttttccca tcatattcgt atcacctcga catctccaat
    20521 caaggtatta gtaataatct tcaatctacg agggttttca tcataatcac tgctgtagat
    20581 tttgatttgt tcatttttca aagaaaattg ctcttcttca aacaagacat ttcctactaa
    20641 tgtcgcatgc tctaatcgga tggctacgcc caaaggtact aagatccgtg ttctgcctat
    20701 cccttttctt acaatcacaa tattatcatc ttttggcaaa agcgtattgc ccaaatctat
    20761 gatagtatca ccagaaatga cggcgatgtt gatatcgtcc cattcataga cgtcgtttcc
    20821 aatacgttgg ttaccgaata attgctgtct tttccgctca ttattatgtg tttttaattg
    20881 ctctgtttgg atcatcatga tctgtttctt tcgccaaaaa gcatttttgg ttaaatctat
    20941 ccctgaaatc tctacacctt tcagaccaat aaataaaacg gcaaatacag ccatcatcca
    21001 taaagcagga ctgttgacta agctaaaaaa aatgaccaaa cttcctaata tcaattgaaa
    21061 attttgaaat ttagtacgag gatgtttgcg catagctaga tatatattga aaataccgaa
    21121 tatcactaaa agcaaaagtc cagtattgtt tacgatttgc caaacagcaa ataacagcag
    21181 tagtgcttca actaccacaa aaaaacgcca agaactattc atcgctcttt ctccctcctg
    21241 acacattctc atttcatcat acctattttt ttaactgttg gctataggac tttagatgta
    21301 agatcgtttg ttgaaatcta aaatacacaa agagaaaaag atctagagtg tatcatcagt
    21361 aagatgaact ctctagatct ttcagtcaga ctacgcttgt tctactttga cgattttaac
    21421 taacatatcg ccacctggag tagcaatagt tacttcatca tttttacgtt tgccaatcaa
    21481 tgcttgcgca ataggagaat cattggaaat tttgccagaa aacggatctg cttcagcgct
    21541 tccgacaatc gtgtactctt cttcttctcc atctggtagt tcgatgaatg taactgtttt
    21601 accaattgat acctcatctg catctacacc gtcgttatcg atgatttgag caaaacgaat
    21661 catattttca attgttgtga ttcttccttc aacaaatgct tgttcatctt tcgctgattc
    21721 atattcagag ttttcggaaa gatctccgaa accgcgggca attttgattc gttcaatgat
    21781 ttctccgcgt ttgactgttt ttagttcttc taattctttt tctaattttt ctttaccttc
    21841 tagagtcatt ggataaactt tctctaccat gtgtaacgtc tccttttttc gataaaatac
    21901 cgcaaaaggt aatcttttga ggaatatagt ccaaaaaaga ttaccacgct tttcttcaaa
    21961 tgtaaatgtt tttctaaaaa tgatcaatgt ctagagcctg tttttctaag aattatttac
    22021 atatttttcc actaattcca tatgttcttc ataagtttta gcgaaataaa catttccagt
    22081 gctcgtatct gctacgaaat aataatagtc attttctgct ggttctaata ctgccttgat
    22141 tgcctcttcg cttggattgt caaaaggtcc aggtccatag ccggtattgg tatacaaatt
    22201 atatggtgaa tctacagctg tatcttcata cgtcactaat tctttgtgtt cacctaatgc
    22261 gtataaaaca gagatatctg actgaagtgg catatttgct ttgattcggt taaagaagac
    22321 ttgtgcaatg tttttacgat cattttcttt tacgccttct ttttcaacta gagaagctag
    22381 agttaaaact tcttgtacag tcaaattttt ctgcttgata gctgaataat agttttgcat
    22441 gaccgtattc gtcttgttca ccatttcaat cactagatcc ttaagcgaag tactcgtgta
    22501 ataatcatat gtggctggga ataagtaacc ttccaaacgg tattttgtgt tctcagcttt
    22561 agatgcactt tccaacagtt ctgggaattt ttggtgcaac tcgttaaaga aagtctcatc
    22621 attcactaaa tctaaaaatt ctttcttgtc tttaccagtt accttcgcta cccgttcagc
    22681 aatctgatcg atatcgtacc cttctggaat ggcaattttc ccatctgcaa cttttgttgg
    22741 ctcagaagta ccgccttctt gcaactgttt gccaatctcg tcaagagtca tattaggcgc
    22801 taactgataa tagccagctt gaaagccagt taaattttta aattttgtat aataattgaa
    22861 aacaatcccg cttttaataa tattgtcctt ctccaaaatc tcaccaatct gcttgttaga
    22921 agagccactc gggatctcga cttggactaa ttggtcatct gatttatcta aaggcttcaa
    22981 cccgctatct acataacgat acacggtaaa tccaagaaat ccgccaataa tcaataatgt
    23041 aagagcaatc actaaaatga tcttcctcac aatcttatct tcttttttac gcagatttct
    23101 ccgcttgtcg attatatctg ctgtagctgc cttactggct tcttttttat ctttacttgg
    23161 gtgttgtttg tttcctgaca aaacaactcc tccttactat caagttcgta actttattca
    23221 ttatacatga tatttgaatt ggcgtgaatg attttattta aatattctat caaaaatgta
    23281 agtagtaaat ccattactat aagattaaaa taaatgttat caagatacaa gctattttag
    23341 ctttattctt tctgtaaaaa agaaaggaga ctaaataaac tattatgaaa aaaggaaaac
    23401 atgctaaaaa aagaaaatat tcatttttaa tgatcgttgt cgtgttgttt agccttagtg
    23461 cgttctctac aggaactatt cttggatggc aattttacaa taatgaacac tctcagatag
    23521 ttgcccatgc tcaatcagct caaaaaaagt tgatactgac taccaatgaa caacagctcg
    23581 ttgaaaaaat cgatcaacta ttaagaaaaa atgattatat tggctcaatt tacgtaaaga
    23641 aaaataatcg catcatcatg gaaaaaggct atggctatgc gaataaactc acgcaacaac
    23701 caaatgatcc ttctctttat tatcagattg gttcggttca aaaagcattg actactcttt
    23761 tgattttaaa acaagtcgag cgtgggcacc tttctttaga tactaagctg gctcaattct
    23821 atccacaaat tgctggcagc cagcaaatta ctatccgtga cttgctgtat atgcgctcag
    23881 gcttgcaccg aactgcttct ccaaccatac cgatgactga tgaagaagtc gttcaatttg
    23941 cgattcagca cttaaaattt acagattatc agacctctca ttatgattca ttgaacttta
    24001 ccatattgac tggaattttg atcaaattaa caaatcaacc gtatgaaaaa ttattgaccg
    24061 atgatatcat cgaaccttta ggattacagc atacaaaatt ttatgaccaa gtcaaaaatt
    24121 catccaatca tgcactatcc tatcaaatgt ctaaagagga tgattacttt aaaccactga
    24181 cagaatctga aacagagatc cataacgaat tagggactgg taatatcagt atgtccgtct
    24241 atgatttaaa tacgctgttt acacaagttt tatctggaaa actagtttcc aaagacttac
    24301 tcttctcatt atggcgtgaa aatgcgaatg gacatccata tagtggtggg gtatatagcg
    24361 gagataatta tatcctgtcg caaggaaata tcgactcttt tgatacatct gctatattta
    24421 gcaaagattc acaggatgct atcatcatgg aaagcaatat aaaagctgac aaaactatca
    24481 aactgcctac tgctgatcta agaaaccaaa tctatgacct gatggaagga actactaagt
    24541 tggcaaatag ctgatatgat gaaaagatag caaatactac ttctttgaat agcatttgct
    24601 taaaaaaagt actcgactaa acgtaggaaa gagtgtggga caaatctaaa aatcaatttt
    24661 tgctacagac tttaattcca aataaacaga acagaaagag gtgttcttct ttctgttctg
    24721 tccaaattat tctaagattt ctctttacca acattatttg acaaagggcc tattaaatct
    24781 aaaatagtat ctttagattg ctaaaatatg tgctagcaaa tcattcatgg cttgttctta
    24841 tttttaattt tatgcaataa aaaagaagaa caattagcgt gattatagaa ataaataatg
    24901 agattttaga aaaaaatgtg tatgaatacc tgattgttac tttatttatt ccactttcac
    24961 tttttactgt aacaaaagga cctccttgtt ttagtactgt agcatttttt gaattaacag
    25021 taaccgttaa tcctttatac cggaatacag gtaaaactat tgttttgcct tttgaagatt
    25081 taaacgtaaa tgtaatttca tctttatttg gagaaaagct actataaata acttgaccat
    25141 cttctgtaac ttgatggttt ttcaaaagca attgatcttt tttatagcct ataggtacat
    25201 aatcaaaatt ctcaaattct tcaagtttat tttccatttg ttcattagaa taagttcctt
    25261 gaaaattcat ttctttcacc atgttaacta ctgatgaata atttaaaatt gaaatagcta
    25321 atattaataa tagtataaaa tttcttctcc ttgtataaga aaatttttcc aactgtggag
    25381 aaataaatag agatactgaa aaagatatga acaatgttga aaatatcata aaacgccaag
    25441 gagcttgaat aatatttaaa ggagtatttt gtaaggcaaa ccatggaaat atttttgtac
    25501 aaagtagaat agatattata cccattatat aagtgatttt agataagatt cctaattttt
    25561 taaagttaaa tgttagtata attaaacaaa taagcaaagt taagccaata ccaaatgata
    25621 gtaattctga atctatactt ccaatcaaaa a
//
LOCUS       DAZKKZ010000042        25644 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.043, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000042 DAZKKZ010000000
VERSION     DAZKKZ010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 25644)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25644)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25644
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.043"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            131..3658
                     /locus_tag="ACG8LA_001837"
     CDS             131..3658
                     /locus_tag="ACG8LA_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family protein"
                     /protein_id="HFQ0204133.1"
                     /translation="MSLQFILGNGKKDHRQVLIDEASAWLDQDASNQVFFLVPNYSKF
                     EQEQEILAEMRRRSGKKTFSTTNVQVFSFYRLAWYLLQQTTLLTGNELSESGSAMILR
                     QILEKNEEELTIFRGEINKRGFIRQLQELYSELRTGNIQPEDLMLLFGDSPNAEDQQL
                     KMKDLKLIFSAYDSELTQRALTNEDALSILANYMQTQDFNNVKFIVSGFSRINGQEYQ
                     LLQAMMEKGQLVVDLLLDRPYTADLPEVLTLFHETGKLYFRLFQSARERKVPILVDRF
                     APEQTRPTELQLLQTMWEETSSQKKAAVHKIGGQEHLHLWEAENPTEEVRQLAVEIRR
                     LVSEENYRYRDIQVLTKNMSLYGNILRPIFQEMAIPFYIDEEQMMENHPLIEWINSLF
                     ALDRYSYRLSDIMRFFKTELFLSTEAETELDEWKQERDEFRKKLDITENVALAYNYQG
                     TYWTREKDWQFVAYDFEAEQIEDVQYLEEQSNTIRRLFQKAVPVFLKKIKKSKTGQEA
                     ANVFYQFLIQSGVQQQLLFWRNQEVDRGNLEAARNHEQTWGALIDLLDEYVVIYGESA
                     FDWSLFQEIITSGLENLSYGKIPTAIDQVRINRLELVRPNQAAVTFALGLNDQVFPDR
                     KETKGLLSSEEREVLNQALPDGQFLFDPSKESISFEPFQAYLVFLSGTDRLYLSYAQS
                     YDTDGSLKMSPYLRRITEYLSVPVERKEHLTIESDPNCYVGTYRSGINTVNRIYRLAL
                     DEKKPVPKHWQKLKELVLNSSWRNFALQIFESQEHLNVPVSMPEKMAEELYGKEIYTS
                     ISRMENFYNCEYKYFMQFGLKLKERTVYGLTPAATGDFYHESLDRFFKLLFSNQLSLV
                     NMSDAQRRDFTEKVLQEVFGELRFEILDSSARMNYIRYQLGQTIQKVTWALQKQSKNT
                     GMHPLQTEILFGQIAGAKGITGLELPLSNGGKLHVRGKIDRIDVASEQEDTWLSVVDY
                     KSSGRSFDVTEAYYGMAMQLLTYLDVALMDAVRLTGKAAVKPAGSYYLHVHNPVLTET
                     DDVEKNTLKKFSYDGVFVDDPALLEVLDHSLEAKEQSLIYPVKKNAKDEYQKGSFSKD
                     KFFTEEELQLFMAHNRENMRLAGDAITSGEIKLNPAYKDKQRIACEFCPFRSICTFDV
                     MLKENNYHRLEKIDKEEALRRILKRSEEE"
     gene            3655..7377
                     /gene="addA"
                     /locus_tag="ACG8LA_001838"
     CDS             3655..7377
                     /gene="addA"
                     /locus_tag="ACG8LA_001838"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0016818 - hydrolase activity, acting on
                     acid anhydrides, in phosphorus-containing anhydrides
                     [Evidence IEA];
                     GO_process: GO:0000724 - double-strand break repair via
                     homologous recombination [Evidence IEA];
                     GO_process: GO:0006302 - double-strand break repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HFQ0204134.1"
                     /translation="MNQIPLKPQNERFTDDQWQAIFDQGDNLLVSASAGSGKTTVLVR
                     RVIEKLKMGFDIDELLIVTFTEAAAREMKERIQEALQESVNSESDPVRRQHFTKQLVL
                     LPTANISTLHAFCLTVIRRYYYLIDIDPVFRMLTDETETILMKEDVWDELREALYAEN
                     DERFFQLTMNFSNDRSDDGLTNLVFSLYEFARANPDPQKWLEQLSDNYRLPEGLAKSR
                     LYQKQIRPLVLADIYQCVQLYEQMTQLAQGEGLEKMHEQVAGEQQQIKNIYEAFSQDR
                     LEEAYAGLEQLTFSTFKSSRKAELKEISNEVKGMRDKAKKLIQQISKSYFPVSPSQME
                     ELTDKALPLVEEMTKVTQSFMDGFSMRKREKGVLDFNDLEHLALQILTEKTKDVWLPS
                     EASKHYRKKFKEVMVDEYQDVNQLQEAILYWLREPDDTKGNMFMVGDVKQSIYSFRLA
                     DPSLFIGKYENFSKKEGGRRIVLAENFRSRKEVLSFTNLIFEQLMDPAVGQINYDEAA
                     KLIQGFSDFPENEQFEPEIMIYEKEQEESEIEIPTDDILEDKTEGELFMTGLKIRQLI
                     DSSFMIYDKKSKKSRPIEYKDIVLLTPTKKNNLTILEIFKTLDIPLEMNDAQNYFQAT
                     EIRTMISLLQLIDNPYQDIPLAAVLRSPIVGLIEPELASIRLANRAHTYYDAVLAYQA
                     SNEDELAAKLEHFGKQLEHWRELARRSSITDLLWDIYYETGYLEYVVGLPAGAQRQAN
                     LYALVDRAKAYEQSSFRGLYQFVRFIEKMQEKDKDLAEPVISIEDNAVRVMTIHASKG
                     LEFPVVFLLDMTKEFNLQDLRNRYAFEEKLGAGIRYMDPETRVLYDTLPFQAIKLAKQ
                     NKLLSEEMRKLYVGLTRAEQKLFIVGSYKNKEQMIQTWSEAADHEELVFDPALRLKGR
                     SSLMNWIGYGLIRHPEMQKYLEEEISTSLLQHSNAQFSISWMNQQSIIEQRQLLAEKE
                     LVNLDQQMKEDETLLADSLQKRLAYEYPYQASSQTTSYQSVSEIKRLFEDPDDTQESR
                     LTLESSQNKAASRQFRYTQEQLAEPKFLQKDRQVSAAAVGTATHALLQLLPLEMPTTE
                     SIHQKLQELVRKRLVDEKVAKKVDVSSIIWFFQTELGQQLIANKENVKREQPFSMLLP
                     ADEVFQDYPNQEDELLIHGIVDGYLEEKDHLNIYDFKTDFILHPDDPAEIDAIVQKYQ
                     GQLRLYQQAMSEALNKPVENVFLILLRVKQIININK"
     gene            7446..7787
                     /locus_tag="ACG8LA_001839"
     CDS             7446..7787
                     /locus_tag="ACG8LA_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HFQ0204135.1"
                     /translation="MELTQTEFVLCPKFEKTFSILGKKWNGLIIDVLLENGPQRFVEL
                     AAKIPMVSDRVLVERLKELEKEGIVTRNFACSEKSRSEYLLTEKGADLQKAMRQIQVW
                     SEKWITEEECG"
     gene            8096..9139
                     /gene="pheS"
                     /locus_tag="ACG8LA_001840"
     CDS             8096..9139
                     /gene="pheS"
                     /locus_tag="ACG8LA_001840"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006432 - phenylalanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HFQ0204136.1"
                     /translation="MSLQAQLESLKEATLVKITAAQDLNELNQIRVETLGKKGPITEV
                     LRGMKDLSPEERPKVGSFANEIRDLLTEEIERKKQVLEEEALNAALAKETIDVTLPGR
                     KVKHGTRHIVTQIMEEIEDIFVGMGYQIVEGYEVESDHYNFERMNLPKDHPARDMQDT
                     FYISDEILIRTHTSPVQARTMEKHDFSKGALRMISPGKVFRRDTDDATHSHQFHQIEG
                     LVVDKNITMGDLKGTLEVVMKKMFGEDREIRLRPSYFPFTEPSVEVDVSCFKCGGAGC
                     NVCKYTGWIEILGAGMVHPNVLKMSGIDPEEYSGFAFGLGPDRVAMLRYGVNDIRNFY
                     QNDLRFLSQFKGE"
     gene            9144..11564
                     /gene="pheT"
                     /locus_tag="ACG8LA_001841"
     CDS             9144..11564
                     /gene="pheT"
                     /locus_tag="ACG8LA_001841"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006432 - phenylalanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HFQ0204137.1"
                     /translation="MLVSYKWLNRYVDLSNVTPKELADKMSVTGIEVEGVTVPEEGLK
                     KIVVGEVKECVPHPDSDHLSICQVDIGEDELSQIVCGAPNVKVGIKVIVALPNSRIAG
                     NVKIKKGKMRGQVSNGMICSLQEIGYSDSVIPKEYAEGIYYMPQEAVNGDPVFPYLDM
                     DDSIIELSITPNRADALSMRGVAYEVGAIYRQTPTFDDEKLVESSRPASDKIQVEVED
                     KEAVPAYQIRIIEGVRIQPSPQWLQNLLMNEGIRPINNVVDVTNYILLLFGQPLHAFD
                     YDKLKSKEIFVRRAKENETLVTLDGESRELTTDNLVITNGKEPVALAGVMGGLDSEIT
                     NETTTVALESALFDPISIRRTAKQFNLRSESSARFEKGINHATVGEASEVAAAMIVSL
                     AGGEVLQGAVKGSEIKAEDVSVKISLERINQYLGTSLVVKEVNEIFEALGFSYEEKEY
                     VYSVVVPPRRWDIQIEADIIEEVARIYGYDQLPSTLPSGETVAGSLSKEQETTRKIRT
                     IFEGSGLSEAISYALTTEEKSRQFVINESNITRLDWPMSEERSVLRMNLISGLLDDIS
                     YNTARKNTEIALYEIGRVFFQENDPRTHLPQEVKHAAIAISGIWEEKDWQTKAQNVDF
                     FTIKGLLENLFEQLGITEDVHYQTVTEMKEMHPGRTAAIYLGEKFIGFVGQVHPTITK
                     SYDIPETYVAEFDLSAIVEAAQKGIVFEAVTKFPAVSRDIALLVKETVTNQELTEVIR
                     SAAGRFLTDIQLFDVYQGENIEKGHKSMAYSLTFVNPEATLTDEEINKAMEKVEKALV
                     ENLEASIR"
     gene            complement(11734..12744)
                     /gene="trpS"
                     /locus_tag="ACG8LA_001842"
     CDS             complement(11734..12744)
                     /gene="trpS"
                     /locus_tag="ACG8LA_001842"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004830 - tryptophan-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006436 - tryptophanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HFQ0204138.1"
                     /translation="MKNIILTGDRPTGKLHLGHYVGSLKTRVAMQADEDNQLFVMIAD
                     MQALTDNAKNPEKVSSNVLQVALDYLAVGLDPAKSTLFIQSQIPELAELTMYYLNLVS
                     VGRVRRNPTVKTEIEQKKFGESVPTGFFIYPVSQAADITAFKANLVPVGEDQKPMLEQ
                     TQEIVQSFNHTYGEVLVEPKGVFPPKGMGRLPGIDGNGKMSKSLGNGIYISDPADVLQ
                     KKVMSMYTDPNHIHVQDPGQVEGNMVFTYLDVFGTDKEAIEEMKAHYRRGGLGDVKIK
                     RYLIDVLEAEFAPIRARREELEKDPSAVMEILRKGSEEAAKVAAQTLSEVKSAMGINY
                     FH"
     gene            12998..13735
                     /locus_tag="ACG8LA_001843"
     CDS             12998..13735
                     /locus_tag="ACG8LA_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HFQ0204139.1"
                     /translation="MAMIKFDHVDKYYGKFHALKNINLEFEKGEVVVVIGPSGSGKST
                     MLRCINGLETISSGKLLINDTDLHDKKTKLTEVRKNIGMVFQHFNLYPNKTVLENIKL
                     APIKVLKQDQATAVKNAEKFLKTVNMLDKKDSYPSMLSGGQQQRVAIARGLAMNPEML
                     LFDEPTSALDPEMIGDVLDVMKKLAHDGMSMIVVTHEMGFAKEVADRVIFMADGEVLE
                     DSRNVRDFFENPNEVRAQQFISKVINH"
     gene            13749..14564
                     /locus_tag="ACG8LA_001844"
     CDS             13749..14564
                     /locus_tag="ACG8LA_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HFQ0204140.1"
                     /translation="MRRLKKIRLIFLLGIAFLALAGCKGNGLANEDILERSKSTNEII
                     WGVKYDTRLFGMMDIESRTVQGFDVDIAKAITKKILGDNGKTEFVEVTSKTRIPLLKN
                     GNIDAIIATMTITDERKKQVDFSDVYFDAGQALLVKKGSQIKSVDDLNASTTVLAVKG
                     STSAANIRQHAPDAKILELENYAEAFTALQSGQGDAMTTDNAILLGIADENPEYELVG
                     GTFTNEPYGIAINKGQENFLKAVNQALEEMHADGTYDKIYQKWFPNETEGKVE"
     gene            14577..15224
                     /locus_tag="ACG8LA_001845"
     CDS             14577..15224
                     /locus_tag="ACG8LA_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HFQ0204141.1"
                     /translation="MSELIQTYGPIFVDGFKITLFSSVLALVFSLIIGTLMAIFQLSK
                     NKVVSALAKAYVEFFRNIPLLIIVMFFYVVVPIYWFNLDGFQAGTIGLTIYTSAFIAE
                     TVRSGIQTVPKGQTEAGLSSGFTYSEIMRYIVLPQAFKIVIPPLGNQFINLVKNSSIL
                     AIVAGLDLMYQGDLIASETFNTFDTYIIVGLFYLVITLPLSYLMVYLEKKWAVRS"
     gene            15240..15896
                     /locus_tag="ACG8LA_001846"
     CDS             15240..15896
                     /locus_tag="ACG8LA_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HFQ0204142.1"
                     /translation="MDFSGAFSWMNIRFLLEGLKVTVEVSLFSIIFSFLIGGLTGVIR
                     FANIPFFSKILGVVIDIIRNLPLLLIIFFTYFALPQIGIQMNIFWSAVAALTIFESAM
                     LSEIFRAGLNAVPKGQMEAGLSTGLTYVESMRTIVLPQAFKSMIPAIVSQLISLIKDT
                     SLAVIISLPELSHQARIIYGQNTNYVLPMFIIMTLMYFVVCYALSLLSGYLEKRRYSY
                     "
     gene            16058..16879
                     /gene="racE"
                     /locus_tag="ACG8LA_001847"
     CDS             16058..16879
                     /gene="racE"
                     /locus_tag="ACG8LA_001847"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008881 - glutamate racemase activity
                     [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HFQ0204143.1"
                     /translation="MIRLTDNRPIGFIDSGVGGLTVVKEALKQLPNENILFVGDTARC
                     PYGPRPAEQVIQYTWEMTDYLVEQGIKMLVIACNTATAVALEEIKAALSIPVIGVILP
                     GTRAAVKKTQNKQVGIIGTIGTVKSQAYEKALKEKVPELTVTSLACPKFVSVVESNEY
                     HSSVAKKIVAETLAPLTTKKIDTLILGCTHYPLLRPIIQNVMGENVQLIDSGAETVGE
                     VSMLLDYFNLSNSPQNGRTLCQFYTTGSAKLFEEIAEDWLGIGHLNVEHIELGGK"
     gene            16882..18237
                     /gene="rph"
                     /locus_tag="ACG8LA_001848"
     CDS             16882..18237
                     /gene="rph"
                     /locus_tag="ACG8LA_001848"
                     /EC_number="2.7.7.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0009022 - tRNA nucleotidyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HFQ0204144.1"
                     /translation="MRHDGRKAQELRKLELQTNVFKYPEGSVVIRFGDTTVICSATIE
                     NSVPPFLRETGTGWVTAEYSMLPRATSTRNRRESSKGKLSGRTMEIQRLIGRSLRAVV
                     DLEKLGERSIIVDCDVIQADGGTRTASITGAFVALKLAIEKLLREKELSEDPIKEHLA
                     AVSVGILPDGTCVTDLDYQEDSAALVDMNLVMTESGKFVEIQGTGEEATFDGEQLNEM
                     LFFGKNAIEDLIKEQKHALLTEFAQNDERIEETKTIIIATRNPGKAEEFRNMFKEAGY
                     HVKTLLDYPELPDVEETGSTFEENARLKAETIAQLLDQPVLADDSGLKVDALGGMPGI
                     YSARFAGEQKSDAGNNAKLLYELTDVPDEKRTAQFHCTLVFAAPKKDSLVVEAEWPGR
                     VARIPSGENGFGYDPLFIPEGKKQTAAELSSEEKNKISHRAQAMKKLSAEWKQWLEGE
                     R"
     gene            18238..18756
                     /locus_tag="ACG8LA_001849"
     CDS             18238..18756
                     /locus_tag="ACG8LA_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HFQ0204145.1"
                     /translation="MRYLVVSDNHGDRDILVDLVDRYRSEVDIFFHCGDSELEASDPL
                     WDTFQVVQGNCDYGPGFEQKKVIQTGQDTVFMTHGHLSNVRFGLTQLAIEARAATADM
                     VFFGHTHQIGCEMDQKILFLNPGSISQPRGPIQIPSYALIESLDDQISVQYYNRAHQA
                     VEELAFSFSRER"
     gene            18863..19363
                     /gene="cbpB"
                     /locus_tag="ACG8LA_001850"
     CDS             18863..19363
                     /gene="cbpB"
                     /locus_tag="ACG8LA_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0180001 - cyclic-di-AMP binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-di-AMP-binding protein CbpB"
                     /protein_id="HFQ0204146.1"
                     /translation="MIGPIVREMLLENQETFLIPAENVANVMYHHPLSHGLLVLSKVG
                     YSKIPVLGKDDHFVGLVSLSDVVNKMIDLQTISMDPLEGLTVADVTETDVPTIDENWE
                     LEEVLHLLVDSPFLPVVTEDRIFKGIITRKELLKAVNFMVHELERRNILSPKIEELKE
                     QIDIVS"
     gene            complement(19643..20563)
                     /locus_tag="ACG8LA_001851"
     CDS             complement(19643..20563)
                     /locus_tag="ACG8LA_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008381 - mechanosensitive monoatomic ion
                     channel activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HFQ0204147.1"
                     /translation="MFSLLATAGTTDSSGETLTDQAVSKVNAFQRFWDGIDWDAILAA
                     FIQKSLYLIFLIVLFWILHRVGKYLIDKSFNQYSKKAILNESRLKTLHSLLNTIFHYT
                     LGFFFIYAILSAIGVPIGSLLAGAGIAGVAIGLGAQGFMSDVITGFFIIMEQQMDVGD
                     YIKLANLTIEGTVVSVGIRTLQLKATDGTVHFIPNRNITTISNLSRANMQVLLDIRIV
                     PEEGYDKIYEIIDRVNRTLAEKYQEELQTEPSIFGLVDLGNSNFAIRTVCYALNGKQY
                     ALKEEFLSSYVKELTASGFTIPNSPIAVGK"
     gene            20689..21741
                     /locus_tag="ACG8LA_001852"
     CDS             20689..21741
                     /locus_tag="ACG8LA_001852"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004084 - branched-chain-amino-acid
                     transaminase activity [Evidence IEA];
                     GO_process: GO:0009081 - branched-chain amino acid
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HFQ0204148.1"
                     /translation="MIKCGENNEGGKYMQIDWNNLGFSYIKTPWRFIAKWKDGQWEEG
                     ELTEDNYLTIHEGSPALHYGQQCFEGLKAYRRKDGKVNLFRPEQNSRRMNQSARRLLM
                     PMVPEKMFVDAVKQVVKANEDFVPPYGTGATLYLRPLLIGVGENIGVHPAPEYLFVVF
                     CTPVGAYFKGGLKPTNFIVSDYDRAAPKGTGAAKVGGNYAASLLPGTEAKELDYSDCV
                     YLDPATHTKIEEVGAANFFGITKDGKFITPQSPSILPSITKYSLLQLAEERLGLQAIE
                     GDIFIDDLDQFAEAGACGTAAVISPIGGIYHNNNLHVFYSETEVGPVTKRLYDELTGI
                     QFGDIEAPEGWIEVVE"
     gene            complement(21851..22606)
                     /gene="fabI"
                     /locus_tag="ACG8LA_001853"
     CDS             complement(21851..22606)
                     /gene="fabI"
                     /locus_tag="ACG8LA_001853"
                     /EC_number="1.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-ACP reductase FabI"
                     /protein_id="HFQ0204149.1"
                     /translation="MSFLEGKKIVIMGVANKKSIAWGCAEAMLKQGAEIIYTYQNERM
                     KKSLVKLVGEEAFTVECDVSSDESIEKAMNAIGEYAGEIHGLVHAVAYANKEELSGNV
                     SDISRDGYQLAQDISSYSLIAVSKYAQPFLAPNSGIVSMTYLGSERAIPNYNMMGIAK
                     ASLEAAIRYLAAEFSPKGIRVNGISAGAIKTLAVTGVKDYQKLIQLSESRTPDQQGVT
                     IEEVGNACAFLISPLSSGIIGDIIYVDKGVHLS"
     gene            22826..23266
                     /gene="fabZ"
                     /locus_tag="ACG8LA_001854"
     CDS             22826..23266
                     /gene="fabZ"
                     /locus_tag="ACG8LA_001854"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HFQ0204150.1"
                     /translation="MSYVLSATEVMELIPNRYPICYIDYVDTLEPGKKIVATKNVTIN
                     EDFFQGHFPDNPVMPGALILETLAQAGSILILKSEEFLGKRAYIGGINKAKFRQKVVP
                     GDVLKCHFEITKMKGSVGTALSAAYVDDKKVCECEFTFIVNQNA"
     gene            complement(23381..24142)
                     /locus_tag="ACG8LA_001855"
     CDS             complement(23381..24142)
                     /locus_tag="ACG8LA_001855"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFQ0204151.1"
                     /translation="MKKNKVILSISLAAALLFAAGCSANNTTSSSSSTESSKSTSTAE
                     STTASSVDLNALELPQLTKDVAENEDLVEMVTNKGTIKIKLFPEHAPKAVENFMTHAK
                     DGYYNGLTFHRVIKDFMIQGGDPKGDGTGGESIWGEGFETEINNHLYNIRGALSMARS
                     QDPNSNGSQFFIVQNTDDMHDGLLKDDYPQAIIDAYKNGGYPSLDGHYTVFGQVIEGM
                     DVVDAIANIETDSSDKPKEEVKIDKINILQEAKQK"
     gene            24331..25425
                     /locus_tag="ACG8LA_001856"
     CDS             24331..25425
                     /locus_tag="ACG8LA_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HFQ0204152.1"
                     /translation="MGKLGISIYPERSTFEKDKAYLDLAHKYGYKRVFTSLLQINDDK
                     EKVLSEFKEVVDYANSLGMEVMVDINPALFEQLEISYDDLSFFHKMGAYGVRLDIGFT
                     GAEEAKMTRNPFGIKIEINMSSGTNYVDNIMSYSPNTDNLLGSHNFYPHRYSGLGYEH
                     FVFCSEKFRKYNLNTMAFVNSQSAEFGPWPTQDGLCTLEDHRDLEIATQVKHLILTGL
                     IDDISIGNAYASEEELKEMAEAFNADYPTLKVDTEEGITENERICLFDNLHSYRGDRS
                     EYILRSTMTRVYYKDKDFPPHNTRDMHHGDVLIDNEGYGQYKGETQIALKDMKNDGRV
                     NVVGRISDDELFLLDFLKPWSSFKLIENKK"
     gene            complement(25511..>25644)
                     /locus_tag="ACG8LA_001857"
     CDS             complement(25511..>25644)
                     /locus_tag="ACG8LA_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HFQ0204153.1"
                     /translation="VNQTFISSVSNQRNHIPRKSLNYRTPIEIFLSYVQEAFYSSLI"
BASE COUNT         8493 a         4442 c         5408 g         7301 t
ORIGIN      
        1 tttgcgtata cttaaaaaag tagaaatatc agaaccttaa aaggatataa tttgaagaat
       61 atagaacaaa tgttcagtat tttttgatat aataaaggag caccgtatca tgtgttgaag
      121 gaggaaaagc atgtctttac aatttattct tggaaacggg aaaaaagatc accgtcaagt
      181 cttgatcgac gaagcatccg cttggctcga ccaggatgca agtaaccaag tatttttcct
      241 tgttcccaac tacagcaaat tcgaacagga acaagaaatt ttagcggaga tgcgaagaag
      301 aagcggaaaa aaaactttca gcacaacaaa cgttcaagta tttagttttt atcgtctggc
      361 ttggtatttg ctgcaacaga caactcttct tacaggaaat gaattatcag aatcaggatc
      421 tgcaatgatc ttgcgacaga ttttagaaaa aaatgaggaa gaattaacaa tctttcgcgg
      481 agaaatcaat aaaagagggt ttattcgtca attacaagaa ctctacagtg aattgcgtac
      541 aggaaatatt caaccagaag acctgatgct tttatttggt gattcaccta atgcagaaga
      601 ccagcaactt aaaatgaaag acttgaagct gattttttca gcttatgaca gcgaattgac
      661 tcaacgtgca ctaacaaatg aagatgcact atctatacta gcaaattata tgcagacaca
      721 agatttcaac aacgtcaaat ttattgtcag tggtttttct cgaatcaatg gtcaagagta
      781 tcaattactg caggcaatga tggaaaaggg gcaattggtt gtcgatttat tgctggatcg
      841 tccttataca gcggatcttc cagaagtact tacgctcttt catgagactg gaaagcttta
      901 tttccgtctt tttcaaagtg caagagaacg gaaagtccct atattagtgg accgatttgc
      961 accagagcag actcgtccga cagagcttca actgctgcaa acaatgtggg aagagacatc
     1021 tagccaaaag aaagcggcag tacacaaaat agggggacaa gagcatctcc atttgtggga
     1081 agctgaaaat ccaactgaag aagtccgaca attagctgtt gaaatcagac gactagtcag
     1141 tgaagaaaac taccgttatc gtgatatcca agtgctgaca aaaaatatgt ctttatatgg
     1201 aaatatcctt cggccgatct ttcaagaaat ggcaattcct ttttatatcg atgaagaaca
     1261 aatgatggaa aatcatccgc tgatcgaatg gatcaacagt ctgttcgctc ttgaccgcta
     1321 ttcttatcgg ctaagtgata ttatgcgttt tttcaaaact gaattatttc tgtcgacgga
     1381 agcagaaacc gaacttgatg aatggaaaca agagcgagat gaattcagga aaaaactgga
     1441 catcactgaa aatgtagcac ttgcttacaa ttatcaagga acttattgga ctcgtgaaaa
     1501 agactggcag tttgtggcgt atgattttga agcagaacag attgaagacg tacagtattt
     1561 ggaagaacag tcaaatacga ttagacgatt atttcagaaa gctgtaccag tatttttgaa
     1621 aaaaataaag aaaagcaaaa caggacaaga ggccgcaaat gttttttatc aatttttgat
     1681 ccaaagtggc gtacagcaac aattattgtt ttggcgtaat caggaagtag acagaggaaa
     1741 cttagaagcg gcaagaaacc atgagcagac atggggagcg ctgattgatc tgttggatga
     1801 atatgtagta atttatggtg aatcggcttt tgactggtca ctgttccaag aaatcattac
     1861 aagtggtcta gaaaatctaa gttatggtaa aatccctacc gcaatcgacc aagtgcgaat
     1921 caatcgtttg gaattagttc gaccaaatca agctgccgtc acttttgcat tagggttgaa
     1981 tgatcaagtg tttccagacc gaaaagagac aaaaggattg ttgtccagtg aagaacgaga
     2041 agtattaaat caggccttgc cagatggaca gtttttattc gacccatcaa aggaaagtat
     2101 ctcttttgag cctttccaag cctatcttgt ttttctttcc ggaacagatc gattatatct
     2161 tagttatgca caaagctatg acacagatgg ttcgctgaag atgtctcctt atttgcgtag
     2221 aatcacagaa tatttatctg ttcccgtcga gagaaaagag catttgacga tcgaaagcga
     2281 ccctaattgt tatgtaggga cttacagaag cggaatcaat acagtcaata ggatttatcg
     2341 attagcttta gatgaaaaaa aacctgtacc aaagcactgg caaaagctca aagaattagt
     2401 actgaattcg tcatggcgaa attttgcttt acagattttt gaaagtcagg aacatttaaa
     2461 tgttcctgtt tcgatgccag aaaaaatggc ggaagagctt tatggaaaag agatttatac
     2521 ttcaatttca cgtatggaga atttttataa ttgtgaatac aaatacttca tgcaatttgg
     2581 tttgaaattg aaagaacgaa ctgtttatgg tctaactcca gcagcaactg gtgattttta
     2641 tcatgaatca ttggatcgtt tcttcaagct actgttttca aaccaattat ccttagtgaa
     2701 tatgtccgat gcgcagcgta gagactttac tgaaaaagtg ctgcaggaag tattcggaga
     2761 acttcggttt gagatattgg atagttctgc aagaatgaac tatatccgct accagttagg
     2821 acagacgatt caaaaagtga catgggcttt gcaaaaacag agcaaaaata caggcatgca
     2881 tcctcttcag acagagattc tatttggtca gattgctgga gcaaaaggta tcacaggtct
     2941 ggaattaccg ttgagtaatg gtggaaaact ccatgttcga gggaaaatcg atcgaatcga
     3001 tgtagcttct gaacaagaag atacttggct aagcgtcgtt gattacaaat ctagcggacg
     3061 ttcattcgat gtcacagaag cttattatgg catggctatg caattattga cgtatctgga
     3121 cgtagcattg atggatgcgg tacgtttgac tggaaaggcg gctgttaaac cagcaggatc
     3181 atattattta catgttcata atcctgtatt gacggagaca gatgatgtag agaagaatac
     3241 attgaaaaaa tttagttatg atggcgtttt tgtcgatgat cccgctcttt tagaagtact
     3301 agatcattca ctggaagcaa aagaacaatc actgatctat ccagtgaaaa aaaatgcgaa
     3361 agatgaatac caaaaaggta gtttcagtaa agacaaattt ttcacggaag aagaactgca
     3421 actattcatg gcgcataatc gggaaaatat gcggttagct ggagatgcga ttacttccgg
     3481 agaaatcaaa ctaaatccag cttataaaga taaacagcgg attgcctgcg aattttgtcc
     3541 attcagaagc atctgtacgt ttgatgtgat gctgaaagaa aataattacc accgtctgga
     3601 gaaaatagat aaggaagaag cactgcgtag aatattgaaa aggagtgaag aagagtgaat
     3661 caaattcctt taaaaccgca aaatgaacga ttcacagatg atcagtggca agcgattttt
     3721 gatcaaggag ataatctatt agtctctgcg tctgccggat caggtaaaac tacagtgctt
     3781 gttcgaagag tgattgaaaa actaaaaatg ggttttgata tcgatgaatt attgattgtg
     3841 acatttactg aagctgccgc aagagaaatg aaagaaagaa ttcaagaggc attacaagaa
     3901 tccgtcaata gcgaaagtga ccctgtacgt agacagcatt ttactaagca gttagtttta
     3961 ttgcccacag cgaatatctc aaccttacat gctttttgcc tgacagttat tcgacgttat
     4021 tattacttaa ttgatattga tccagtcttt cgcatgttaa cagatgaaac agaaacgatc
     4081 ttgatgaagg aggatgtgtg ggacgagctg agagaagcac tttatgcaga aaatgatgaa
     4141 cgatttttcc aattaacaat gaatttttct aatgatcgtt cagatgacgg cttgacgaat
     4201 ctggtgtttt ctctttatga gtttgcccgt gccaaccctg acccccaaaa atggctagaa
     4261 cagttaagcg ataattatcg tttgcctgag gggctagcga aatctcgatt atatcaaaaa
     4321 caaatccgtc ctttagtttt ggcagatata taccaatgtg tacagttata tgaacagatg
     4381 actcagttag cacaaggtga aggattagaa aaaatgcatg agcaagtagc tggagaacaa
     4441 cagcagatca agaatatcta tgaagcgttc tcgcaagatc ggttagaaga agcttatgct
     4501 ggtttggaac aactaacttt ttcaactttt aagagcagtc ggaaagcaga attgaaagaa
     4561 atttccaatg aagtcaaggg catgagggat aaagcaaaaa aactgattca gcagataagt
     4621 aaaagttatt ttcctgtttc cccaagccaa atggaagaat taacggacaa agcactaccg
     4681 ttagtcgaag aaatgacaaa agtcacgcaa agcttcatgg acggtttcag tatgcgtaaa
     4741 cgggaaaaag gtgtgctgga tttcaatgat ctggaacatt tagcgttgca gattctcaca
     4801 gaaaaaacga aagatgtatg gctgccaagt gaagcttcaa aacattatcg aaaaaaattc
     4861 aaagaagtaa tggtagatga atatcaagac gtgaaccaat tacaagaagc cattttatac
     4921 tggctaagag aacccgatga tacaaaagga aatatgttca tggttgggga tgtcaaacaa
     4981 tccatctatt ctttccgttt agcagatcct agtttattta tcgggaaata cgagaatttc
     5041 tcaaagaaag aaggcggacg tcgaatcgtt ttggctgaga acttccgctc tagaaaagaa
     5101 gtcctttctt ttacgaatct tatttttgaa caactaatgg atccagcagt gggtcaaatc
     5161 aattatgacg aagcagccaa actgatccaa ggattttcag actttccaga gaatgaacag
     5221 tttgagccgg aaatcatgat ctatgaaaaa gaacaggaag aatcagagat tgagattccg
     5281 acggatgata tactggaaga caaaacagaa ggcgaacttt ttatgacagg actaaaaatt
     5341 cgtcaattaa ttgattcctc ctttatgatt tatgataaaa aatcaaaaaa aagtcgtccg
     5401 atagagtaca aagacattgt tctcttgaca cctacaaaga agaacaactt aacgatttta
     5461 gagattttca aaacattgga tattccatta gagatgaatg atgctcaaaa ctattttcaa
     5521 gcgacagaaa ttcgcacgat gatctcgctg ctacaattaa tcgataatcc ctatcaagat
     5581 attccgcttg cggctgtatt gcgctcaccg atcgtgggtc tgattgaacc agaattagcc
     5641 agcattcgat tagctaaccg tgcacatact tactatgatg ctgtgcttgc ttatcaagca
     5701 tcaaacgaag atgaattagc agctaagctg gaacattttg gcaagcaact agagcattgg
     5761 cgagaacttg ctcgccgttc ttcgatcact gacttgttat gggatatcta ttatgagacg
     5821 ggatatctag agtatgtggt cggtctgcca gcaggggcac agagacaagc caatctttat
     5881 gcattggttg atcgtgccaa agcttacgag caaagttctt tcagaggatt ataccagttc
     5941 gtgcgtttca ttgaaaaaat gcaagaaaaa gataaagact tagcagaacc agtcatttca
     6001 atagaagata atgctgttcg cgttatgacg atccatgcaa gtaaaggctt ggaattccca
     6061 gttgtatttt tgttagatat gacaaaggag ttcaacttac aagacttgcg caatcggtat
     6121 gcttttgaag aaaaacttgg agcaggaatt cgctatatgg atcctgaaac acgagtgtta
     6181 tatgatacgt taccgtttca agccatcaaa ttggcaaagc aaaacaaatt gttgtcggaa
     6241 gaaatgcgta aattgtatgt aggattgact cgggcagaac aaaagctttt cattgtcggt
     6301 tcctataaaa ataaagagca aatgatccaa acgtggtctg aagcagctga tcatgaggag
     6361 ttagtttttg atcctgcgct acgtttgaag ggcagaagca gcttgatgaa ttggattggt
     6421 tacggattga tccgtcatcc tgaaatgcag aaatacttag aggaagaaat ttcgacttct
     6481 cttcttcaac attcaaatgc acagttttct atttcatgga tgaatcagca atcgatcatt
     6541 gaacaaagac agttgcttgc tgaaaaagaa ctggttaact tagatcagca gatgaaagaa
     6601 gatgaaactt tattagcaga ttcgttacaa aaacgtctgg catatgaata tccttatcaa
     6661 gcttcttcac aaaccacaag ttatcaatct gtatctgaaa tcaaacgatt attcgaagat
     6721 ccagatgata cacaagaatc acgtttgact ctggaaagca gtcagaacaa agcagcatcc
     6781 cgtcaatttc gttatacgca agaacaacta gcagaaccaa aatttttgca aaaagatcgg
     6841 caagtgtcag cagctgctgt tggaactgct acgcatgctt tgttacaatt actgccatta
     6901 gagatgccaa ctacagagag tatccatcaa aaattacagg aattggtaag gaaacggtta
     6961 gtagacgaaa aagtcgcgaa aaaagtagat gtttcttcta ttatatggtt ctttcaaaca
     7021 gaacttggtc aacagctgat tgccaacaaa gaaaacgtaa aacgagaaca acctttttcc
     7081 atgctgcttc ctgctgacga agtatttcaa gactatccaa atcaagaaga tgaactatta
     7141 atccacggaa tcgtcgatgg atacctagaa gaaaaagatc atctcaatat ctatgatttt
     7201 aaaacagatt ttattttaca tccggatgat ccagcagaaa tagatgcaat cgtccaaaaa
     7261 tatcaaggac agctaagact ttaccaacaa gcaatgtcag aagctttgaa taagccagta
     7321 gaaaatgttt tcctaatttt gcttcgagtg aaacaaatta taaacattaa caaataatta
     7381 taattgagca aacttgactt atgttttgta aggattatgc tatactctgg gaagaggtga
     7441 gtatgatgga gctaacacag acagaattcg ttttatgccc taaatttgaa aaaacattct
     7501 ctattttagg aaaaaaatgg aacggattga ttatcgatgt actactcgaa aacggtccgc
     7561 aacgctttgt tgagcttgcg gcaaaaatcc cgatggtcag tgatcgagta ttagtcgaac
     7621 gcttgaagga attagaaaaa gaaggaatag tcactcgaaa ctttgcctgt agcgaaaaga
     7681 gccgttcaga atatctcttg actgaaaaag gagcagactt gcaaaaagcg atgcgtcaaa
     7741 tacaagtttg gagcgaaaaa tggatcacag aggaagaatg cggttgattt tgtaaaaaaa
     7801 atcttgtaaa ctatagtcca tacgaataag taaagaacga tgacgaaaaa gagtagtttg
     7861 gctaaaccag ttcagggaga tctgtcgcag actgaaagca gatcctgtgt ttgaaaaatg
     7921 aagttcactt tccgagttcg tctgataaaa tcagaccggc aattgtcgtt aacgaagtaa
     7981 gagtgcggtg taagtcattt atccgcaaat taggatggta acgcgaagac ctcgttcctt
     8041 aacaggaatg aggtcttttt gttttgtatt tggaatttaa aggaggaaca agcacatgtc
     8101 tctacaagca caattagaga gcttgaaaga agcaacgctc gtcaaaatca cagcggcaca
     8161 agatttaaat gaattaaatc aaatacgtgt tgaaacgtta ggaaaaaaag gaccgatcac
     8221 agaagtatta cgtgggatga aagatctaag tccagaagag cgaccaaaag tcggaagttt
     8281 cgcaaatgag atccgagatc ttttgacaga agagatcgag cgaaaaaaac aagtattaga
     8341 agaagaagcg ttaaatgcag ctttggcaaa agaaacaata gacgtgacac tacctggtag
     8401 aaaagtaaaa catggtacac gtcatatcgt gacacaaatc atggaagaaa ttgaagatat
     8461 ttttgtgggt atgggctatc agatcgtaga aggatatgaa gtagaatctg atcattacaa
     8521 tttcgaacgg atgaatctgc caaaagatca tccagcaagg gacatgcaag atactttcta
     8581 tatttcagac gagatattga ttcggacaca tacttcacca gtccaagcac ggacaatgga
     8641 aaaacatgat ttctctaagg gtgctctacg aatgatctcg ccagggaaag tcttccgcag
     8701 agatacagat gatgcgaccc acagtcatca gttccatcaa attgaagggc tagttgttga
     8761 taaaaacatc acaatgggcg accttaaagg aacattagaa gtcgtaatga aaaaaatgtt
     8821 tggggaagat cgtgaaattc gtttgcgtcc aagttatttc ccatttacgg aaccatcagt
     8881 agaagtagat gtcagctgtt tcaaatgtgg tggtgccggt tgtaacgtat gtaaatacac
     8941 tggatggatc gaaattttag gagctggcat ggtacacccg aatgtgttga agatgtcagg
     9001 aatcgatcca gaagaatatt caggctttgc tttcggcctt ggaccagacc gcgtagctat
     9061 gttgcggtat ggagtgaatg atatccgtaa tttctatcaa aatgacttac gtttcttaag
     9121 tcagttcaag ggggagtaag aaaatgttag tttcatataa atggctcaat cgttatgtag
     9181 atttatcgaa tgtaacacca aaagaattag cggataagat gtctgtgaca ggaatcgaag
     9241 tagagggagt aacggttcca gaagaaggct tgaaaaaaat cgttgtcggt gaagtcaagg
     9301 aatgcgtacc acatccagat tctgatcacc tttctatttg tcaagtcgat attggcgaag
     9361 acgaactgtc tcaaatcgtt tgtggagcgc ctaatgtgaa ggttggaatc aaagtgattg
     9421 ttgcacttcc taactcacgt atcgctggta atgtaaaaat caaaaaagga aaaatgcgtg
     9481 gccaagtatc aaatggcatg atttgctcat tacaagaaat tggctattca gatagtgtta
     9541 taccgaaaga atacgctgaa ggtatctatt atatgccaca agaagctgta aatggcgatc
     9601 cagtttttcc ttatttggat atggatgatt cgattattga attatctatc acaccgaatc
     9661 gtgcggatgc attgtcaatg cgtggcgtag cttatgaagt tggggcaatt tatcgtcaga
     9721 ctcctacatt cgatgacgaa aagctggtag aatcctcacg tcctgctagc gataaaattc
     9781 aagtggaagt tgaagataaa gaagcagttc ctgcttatca aatcagaatc attgaaggag
     9841 taagaatcca gccaagtcct caatggctgc aaaatctttt gatgaacgaa ggcattcgtc
     9901 caatcaacaa tgtagtagat gtgacgaact atattttgct tttattcgga caaccactac
     9961 atgcatttga ctacgacaaa ttgaaatcaa aagagatctt tgtccgccgt gcaaaagaaa
    10021 atgaaacatt agtaacacta gatggagaat ctcgggaatt gacaactgac aatctcgtca
    10081 ttactaacgg caaagaacca gttgctttag ctggtgtcat gggagggtta gactcagaga
    10141 tcacgaatga aacaacaaca gttgcactag aatctgcttt atttgatcca atttcgattc
    10201 gtcgtacagc aaaacaattt aatttgcgta gtgaatcctc tgcacgtttt gaaaaaggaa
    10261 tcaaccatgc gactgttgga gaagccagtg aggttgctgc agcaatgatc gtttctcttg
    10321 cgggtgggga agttctacaa ggcgcggtca aaggctcaga gatcaaagca gaagacgtat
    10381 cagtgaagat ttcacttgaa cgcatcaatc aatatttagg aacatctctt gtcgttaaag
    10441 aagtaaatga gatttttgaa gcacttggat ttagctatga agaaaaggag tatgtttatt
    10501 ccgtagtagt accaccaaga cgctgggata tccaaatcga agcagatatt atcgaagaag
    10561 ttgctcgtat ttatggatac gaccagttgc catctacact tccaagtgga gaaacggttg
    10621 ctggaagctt gtcaaaagaa caagaaacta ctcgtaaaat tcgtacaatc tttgaaggaa
    10681 gcggattgag cgaagcaatc agttatgcat tgacaacaga agaaaaatca agacagtttg
    10741 ttataaatga aagtaatatt acacgtttgg actggccaat gagcgaagaa cgttctgtat
    10801 tacgaatgaa tttgatcagc ggactattag atgatatcag ttataacact gcccgaaaaa
    10861 atacagagat tgctttatat gaaattggtc gggtgttctt ccaagaaaat gatccacgta
    10921 cacatctgcc gcaagaagta aaacatgcag caatcgctat ttctggtatt tgggaagaaa
    10981 aagattggca gacgaaagct caaaatgtag actttttcac catcaagggt cttttagaaa
    11041 acttatttga acaactaggc atcactgaag atgtccatta tcaaacagtg acagaaatga
    11101 aggaaatgca tcctggaaga actgctgcga tttaccttgg cgaaaaattt attggttttg
    11161 tcggtcaagt gcatccaacg attacaaaaa gttatgatat tccagaaaca tatgttgctg
    11221 agtttgattt atctgctata gtggaagctg ctcaaaaagg gatcgttttc gaagcagtga
    11281 caaaattccc agcagtcagc cgggacatcg ctttgcttgt aaaagaaact gtgacaaatc
    11341 aggaattaac agaagttatc cgttctgctg ccggaagatt tttaacagat atccaattat
    11401 ttgatgtcta tcaaggagaa aacattgaaa aaggacataa atccatggcg tatagcctga
    11461 cattcgtcaa cccagaagca acattgacag atgaagaaat caataaagca atggaaaaag
    11521 tcgaaaaagc gttggtagaa aacctagagg caagtattcg ctaagaagga aaatatagta
    11581 agtaacgatc aagtagcttt tgaagaccat acatttgaaa aaaagatgtg acacaacttc
    11641 gtcacatctc tttttttgat tttaaaaaag gaatagcaca gagacgagat aaaaaaacag
    11701 gcctttacag cctgcttttt tagagtaaat gaattaatgg aagtaattga ttcccattgc
    11761 tgattttact tcagaaagtg tttgtgcagc tactttagca gcttcttcac tacctttacg
    11821 taagatttcc ataacagctg aaggatcttt ttccaattct tctcggcgcg cacggatcgg
    11881 tgcaaattca gcttccaata catcaatgag gtatcgtttg atctttacat caccaagtcc
    11941 gccgcggcgg taatgagctt tcatttcttc aattgcttct ttatctgttc cgaatacatc
    12001 caagtaggtg aagaccatat tcccttctac ttgtccagga tcttgtacat ggatgtggtt
    12061 tggatcagta tacatactca tgactttttt ctgtaagaca tcggcaggat cggagatata
    12121 aataccgttt cctaacgatt tactcatttt gccatttcca tcgattccag gtaatctacc
    12181 cattcctttt ggtgggaata cgccttttgg ttccaccaag acttcaccat atgtatgatt
    12241 gaagctttgt acgatttcct gtgtctgctc tagcattggt ttttgatcct caccaacagg
    12301 tacaagattc gctttgaatg cagtgatatc tgctgcttga gaaacaggat agataaagaa
    12361 tcctgtaggc acgctttcac cgaatttttt ttgttcgatt tctgttttga cagtcggatt
    12421 gcgccgaacg cgtcctacgc tgactaagtt caaataatac atggttaatt cagctaattc
    12481 cggaatttgt gattggataa ataaagtaga ttttgcagga tctaatccca cggctaaata
    12541 gtctaaagca acttgcaaga catttgatga aaccttctca ggatttttag cattatctgt
    12601 cagtgcttgc atgtcagcaa tcatgacaaa cagttggttg tcttcatctg cctgcatagc
    12661 cactcgggtt tttagagaac cgacgtaatg ccctaaatgc agcttcccag ttggtcgatc
    12721 tcccgttaaa ataatatttt tcaaaaaaga cacctcttta cgatttgtaa gtctgagcac
    12781 ttaatatctt accgtttttc ctgaaaagaa acaacagttc ctaaggaaaa aacaaggaaa
    12841 gaggataaaa taactaatag attagaaatg gaagaaatat ttatgggaga ataaacgttc
    12901 taagaaactt tacaaattac taaactatca gatataatgt attttattat acatctttaa
    12961 aagaaatctt actaaataat aatgggagtg taattctatg gcaatgatta aatttgatca
    13021 cgtggataaa tattatggca agttccacgc attaaaaaat atcaatctcg aattcgagaa
    13081 aggagaagtt gtcgttgtca ttggtccttc tggttcagga aagagcacga tgcttcgctg
    13141 tatcaatgga ttagagacga tctcttcagg taagctgctg attaatgata ctgacttgca
    13201 tgataaaaag acaaaactga cagaagtccg aaaaaacatc ggcatggttt tccaacattt
    13261 caatttgtac ccaaataaaa ctgttctgga aaacatcaaa ttagcaccaa tcaaagtgtt
    13321 gaagcaagac caggcaactg cagtcaaaaa cgcggagaaa tttttgaaaa ctgtcaatat
    13381 gttagataag aaagattctt atccttccat gttatccggg ggacaacagc aacgggtggc
    13441 aatcgccaga ggtttagcga tgaatcctga gatgctgctg tttgatgaac ctacttctgc
    13501 tttggatccg gaaatgattg gtgatgtatt agacgttatg aaaaaattgg ctcatgacgg
    13561 tatgtcaatg attgtcgtga cacatgaaat gggctttgcc aaagaagtgg cggatcgtgt
    13621 tatcttcatg gctgatggag aagtattgga agacagcaga aatgtgagag actttttcga
    13681 aaatccaaat gaagtccgag cacagcaatt tatcagtaaa gttatcaatc attgatagga
    13741 ggaaaaagat gcgcaggtta aaaaaaatac gcctgatttt ccttttaggc attgcttttc
    13801 ttgcactagc cggatgtaaa ggaaatgggt tggcaaatga agatatttta gagcgaagca
    13861 aatctaccaa tgaaatcatc tggggtgtca agtatgatac tcgattattt ggaatgatgg
    13921 atattgagag cagaactgta caaggatttg atgtagatat tgcaaaagca atcactaaaa
    13981 agatccttgg tgacaatgga aaaacagaat ttgttgaagt cacttctaaa actcggattc
    14041 cattattgaa aaacggaaat atcgatgcaa ttattgcaac gatgacgatc acagatgaac
    14101 gaaaaaaaca ggttgacttt tcagatgtct atttcgatgc tggccaagct ttgttggtaa
    14161 agaaaggaag ccaaatcaaa agtgtagatg atttgaatgc ttctacaacg gttctagcag
    14221 tcaaaggttc tacatcggct gcgaatatcc gacagcatgc accagatgca aaaattttag
    14281 aattagaaaa ctatgcagaa gcatttactg ctttacaatc tggtcaggga gacgcgatga
    14341 ctacggataa tgcgattttg ttagggattg cagatgaaaa tccagagtat gagttagttg
    14401 gtggaacgtt tactaatgag ccttacggga ttgcgatcaa caaagggcaa gaaaacttct
    14461 tgaaagctgt taaccaagcg ctagaggaaa tgcatgcaga tggcacatac gataaaatct
    14521 atcaaaaatg gtttccaaat gaaactgaag gaaaagtaga gtaaggggga gaggcaatga
    14581 gcgaattgat acaaacttat ggaccaatct ttgtcgacgg gttcaagatc acattgtttt
    14641 cgagtgtctt agcacttgtg tttagtttga ttatcggaac gttaatggca atcttccaat
    14701 tatcaaagaa taaagtagtg agcgccttag caaaggcata tgtagaattt tttagaaaca
    14761 ttccattatt aatcatcgtg atgttttttt atgttgtcgt accgatttat tggtttaatc
    14821 tagatggatt ccaagcaggt acgattggat taacgatcta tacatctgct tttattgctg
    14881 aaacagtacg ttcagggatt caaaccgtac caaaaggtca aacagaagca ggactatctt
    14941 ctggttttac ctattcagaa atcatgcgtt atattgtttt accgcaagca ttcaaaatcg
    15001 ttatcccgcc attaggcaac caatttatca acctcgtaaa aaactcatct attttagcaa
    15061 tcgtagctgg tttagatttg atgtatcaag gagacttgat cgctagtgaa acattcaata
    15121 ccttcgatac gtatatcatc gttgggttat tttacttagt tatcacgcta ccgttatctt
    15181 acttaatggt ttatcttgag aaaaaatggg cggttcgttc atagaaggag gggaaataca
    15241 tggattttag cggcgctttt tcatggatga atatccgttt tttattggaa ggattaaagg
    15301 ttactgttga agtttcattg ttttcgatca tttttagttt cttgatcggt ggtctgacag
    15361 gtgtgattcg ttttgcgaat atccctttct tttccaaaat ccttggtgta gtgattgata
    15421 ttatacggaa tcttccatta ttattgatca ttttcttcac ttactttgcc ttacctcaaa
    15481 tcggcattca gatgaacatc ttctggtccg ctgtcgcagc attaacgatt tttgagtcag
    15541 ctatgttgtc ggaaattttc cgagctggac tcaatgctgt tccaaaagga cagatggaag
    15601 caggattatc aacgggactg acttatgtag aatcgatgcg aacgatcgtg ttaccgcaag
    15661 catttaaatc aatgatcccg gcaattgtga gccaattgat ttcactgatc aaagatactt
    15721 cattagcagt aatcatttct ttacctgaac tttctcatca ggcacgtatt atttatggac
    15781 agaacaccaa ttatgtgctt ccgatgttca tcatcatgac acttatgtac ttcgtggtat
    15841 gttacgcgct ttctctgctt tccggttact tggaaaagag acggtacagt tattaataga
    15901 tgattctttt agcggttgtg gcaaactaaa gtcacaaccg cttttcctct ttccattcga
    15961 aaaaaagaga tttcgattgt tttaagcaag taagagcact tgaaaattca cgctaaaaag
    16021 tacacaatag ggaggataga atttattgaa aaaaaggatg atacgattga cagataatcg
    16081 ccctatcgga tttattgatt caggtgtcgg cggcttgact gtagtaaaag aagccctgaa
    16141 acaattaccg aatgaaaata ttttatttgt aggagacaca gcacgctgcc catatggccc
    16201 tagacccgcg gaacaggtaa tccagtatac ttgggaaatg acggattatc tggtggagca
    16261 aggaatcaag atgctggtga tcgcctgcaa taccgcaact gcggtggctt tagaagaaat
    16321 caaagctgct ctttctattc cagtcatcgg tgtgatcctt cccggtacta gagcggcagt
    16381 aaaaaaaaca caaaataaac aagttggcat tatcggtacg attggtacgg taaaaagtca
    16441 agcttatgaa aaagcactga aagagaaagt accagaattg actgtgacaa gtcttgcttg
    16501 tcccaaattt gtttcagttg tcgaaagtaa tgaataccat tcatcggtgg cgaaaaaaat
    16561 tgtggcagaa acattagctc ctttaaccac taaaaaaatc gatacattga ttttgggatg
    16621 cacccattat ccattattac gccccatcat tcaaaatgta atgggagaaa atgttcaact
    16681 gatcgattct ggagcagaaa cagtaggtga agtatctatg ctgttagatt atttcaattt
    16741 gagcaattca ccgcaaaatg gtcggacatt atgccagttt tatacaactg gctctgccaa
    16801 acttttcgag gaaatagctg aagactggct tggaatcgga cacttaaatg tagaacatat
    16861 cgaattggga ggaaaataag gatgcgtcat gacgggagaa aagcccaaga gcttcgcaaa
    16921 ctggagcttc aaacaaatgt tttcaaatat ccagaaggat cggtagtgat ccgttttggt
    16981 gatacaacag ttatttgttc tgcaacaata gaaaattctg ttcccccttt tttgagagaa
    17041 acaggaacag gatgggtgac agcagaatat agtatgctgc ctcgagcaac gagtacgaga
    17101 aatcgtagag aaagcagcaa agggaaactt tctggtagaa caatggaaat ccagcgtctt
    17161 attggtcgtt ccttgcgtgc agtagtagac ttggaaaaat taggagaacg tagtatcatc
    17221 gtagactgcg atgtgatcca agcggatggc ggtactagaa cagcaagtat cactggggca
    17281 tttgtggcat tgaaattagc cattgaaaaa cttttaagag aaaaagaatt gtcagaagat
    17341 ccaataaaag aacatcttgc tgcagttagc gtaggaatct taccagatgg gacttgcgtc
    17401 acagatttgg attaccaaga agattccgca gcacttgtag acatgaatct tgtaatgaca
    17461 gaatctggaa aattcgtgga gattcaagga actggagaag aagcaacgtt tgatggtgaa
    17521 cagttgaatg aaatgctctt ttttggaaaa aacgcgattg aagatttgat caaagagcaa
    17581 aaacatgctt tgctaacaga gtttgctcaa aatgatgagc ggatagaaga aacaaaaaca
    17641 atcatcattg cgacaagaaa tccaggaaaa gcagaagagt ttcgaaatat gttcaaagaa
    17701 gcgggatatc atgtaaaaac attacttgac tatcctgaat tgccagatgt ggaagaaact
    17761 ggcagcacat ttgaagaaaa tgcccgatta aaagcagaaa cgattgcaca attgcttgat
    17821 cagccagtct tagcagatga ttcaggtttg aaagtggatg ctttaggcgg tatgccagga
    17881 atctattctg cacgttttgc aggggaacaa aaaagtgatg cggggaataa cgccaaatta
    17941 ttatatgaat tgacagatgt gccggatgaa aaaagaacag cacaattcca ttgtacgtta
    18001 gtattcgcgg cacccaaaaa agacagcctt gtagtagaag cggaatggcc cggtcgagta
    18061 gcccgtatac catctggcga aaatggcttt gggtatgatc ctttatttat cccagaaggt
    18121 aagaaacaaa cagcagcaga attatcgagc gaagaaaaaa acaagatcag tcatcgggct
    18181 caagcaatga aaaaattgag tgccgagtgg aaacaatggc tggaaggaga gagatagatg
    18241 cggtatttag tagtaagtga taatcatgga gacagagata tcctcgttga cttagtagat
    18301 cgttatcgtt ctgaagtgga tatctttttc cattgtggtg attcggaatt agaagcttct
    18361 gacccattat gggatacatt ccaagtggtt caaggtaatt gtgattatgg accaggattc
    18421 gaacagaaaa aagtgatcca aactggtcag gatacagtat tcatgactca cggtcattta
    18481 tcgaatgtcc gatttggttt gacacagtta gcaatcgaag ctcgagctgc aactgccgat
    18541 atggtgtttt ttggtcatac ccatcaaata ggctgtgaga tggatcagaa aatcctgttt
    18601 ttgaatcctg gtagcatttc tcagcctaga ggcccgatcc aaatcccatc atatgctctt
    18661 atcgaaagtt tagatgacca aatttctgtt caatactata accgtgccca tcaggcagtt
    18721 gaagagttgg ccttttcttt ttcgagagag cgctgaataa aaaaactcta atttttaata
    18781 aaaataagct ttattttatg aattttgcat ccggtttcgg taaaatagta gtgttgaatg
    18841 aaatagaaat ggaggccatc agatgattgg acctatagta agagaaatgc tgctggaaaa
    18901 tcaggaaacg tttttgattc ctgcagaaaa tgtggcaaat gttatgtatc atcatccatt
    18961 gtcccatggt ttacttgtgt tatcgaaggt cggttattcc aaaattcctg tattaggaaa
    19021 agatgatcac tttgtaggac tagtaagttt atcagatgtg gtcaataaaa tgattgactt
    19081 gcaaacaatc agcatggacc cgttagaagg actaacggtt gctgatgtga cagaaacaga
    19141 tgttccgaca attgatgaaa attgggaact agaagaagta ctccatttgt tagtcgattc
    19201 gcctttttta ccggttgtca cagaagatcg gattttcaaa ggaatcatta caagaaaaga
    19261 gctgcttaaa gccgtaaact tcatggtgca tgaattagaa cgtcgtaata tattgtctcc
    19321 gaaaatcgaa gaattaaaag aacaaatcga tatcgtgagc taaagaacga gaaactaaaa
    19381 gataatcaaa aaataagtag aaaaaacagc gtaccagttt tgactttatc ttgaaaaaga
    19441 ggctgggaca aaagcgttta actccaagaa ataagaagga attcacgaaa attgcttttc
    19501 aaatttttgt gaatttcagc ttatttccga aggagttgct tctgcttccg ccgtttatac
    19561 gtgtttagag cgtgggacaa aagtgttctt tacttttgtc ccacgctctt tttagtgaga
    19621 ttcgttgcat cgtttgtcca aattattttc cgacagcaat tggactgttc ggaatcgtga
    19681 aaccagaagc tgtcaattct ttgacatagg agctcaagaa ctcttctttt aaggcatatt
    19741 gttttccgtt caatgcgtag cagaccgtac gaatcgcaaa attgctgttt ccaagatcca
    19801 ctaatccaaa gatagaaggt tcagtttgga gctcttcttg gtatttttca gctaatgtac
    19861 gatttactcg atcaatgatc tcatagattt tgtcatatcc ttcttcagga acaatccgaa
    19921 tatctaaaag tacttgcata tttgcacgag agagattgct gatcgtggtg atgtttcgat
    19981 tcgggatgaa atggacagta ccatccgttg ctttcagctg aagggtacgg ataccaacag
    20041 atacgacggt tccttcaatc gttaagtttg ctagcttgat gtagtcccca acatccatct
    20101 gttgttccat gataataaaa aatccggtaa taacatcact catgaaccct tgggcaccaa
    20161 gaccgattgc cacacctgca attccggcac cagccaaaag tgatccgatc ggcacaccga
    20221 tagcagataa aattgcatag ataaaaaaga aaccaagggt ataatgaaaa atagtattta
    20281 aaagactatg taaagtcttt aagcggctct cgtttagaat ggctttttta gaatactgat
    20341 taaaagactt atcaatcaga tattttccca cacggtgaag aatccaaaaa aggacgatca
    20401 aaaaaatcag atataaactt ttttggataa aggcagccaa aatggcgtcc caatcaatcc
    20461 cgtcccaaaa ccgctgaaac gcatttactt tgctgacagc ttgatctgtc aatgtctcgc
    20521 cagaagagtc tgtcgtaccg gcagttgcta ataatgaaaa cataaaatcc tcttttctaa
    20581 aatttgattc tttctgtatt gtaccaagaa gttttcaaaa aaggaaatag caaaaataac
    20641 tataatgaag gaaaaaagct gaaaataaaa tgacaaataa tatggataat gataaaatgt
    20701 ggagaaaata acgaaggtgg taagtatatg caaatcgatt ggaacaatct aggtttttct
    20761 tatatcaaaa ctccttggcg ttttattgcc aaatggaaag acggacaatg ggaagaagga
    20821 gaattgacag aagataatta cctgacgatt catgaaggct ctccagcgct tcattatggt
    20881 cagcaatgtt ttgaaggtct aaaagcttat cgtcgaaaag acggcaaggt caatctcttt
    20941 cgacctgaac aaaatagtcg acggatgaat caaagtgcta gacgattgct gatgccaatg
    21001 gtccctgaaa agatgttcgt tgatgctgtc aagcaagtgg taaaagcaaa tgaagatttt
    21061 gtgccgccct atggaacagg cgctacatta tacttgcgcc ctttactgat tggggtcggt
    21121 gaaaacattg gtgtccatcc agctccagaa tatttatttg tcgtcttctg tacgccagta
    21181 ggagcgtatt tcaaaggtgg actaaaacca acgaatttta ttgtatctga ttacgatcgt
    21241 gctgctccta aggggactgg tgcagcaaaa gtcggcggaa attacgcagc gagtttactt
    21301 ccaggaacag aagcaaaaga actggattac tcagattgtg tttatcttga tccagccaca
    21361 catacgaaaa tcgaagaagt aggtgcagca aatttctttg gaattacaaa agacggaaaa
    21421 ttcatcactc cgcaatcgcc ctctatctta ccaagtatca cgaaatattc cttgttgcag
    21481 ttagctgaag aacgactagg actgcaagca attgaaggag atattttcat tgatgatcta
    21541 gatcaatttg cagaagctgg tgcatgtggt acagcggctg ttatttctcc aatcggtggg
    21601 atttatcaca ataacaatct tcatgtattt tatagtgaaa cggaagtagg accagtaaca
    21661 aaacggttgt atgatgaatt gacaggtatt caatttggag acatagaagc accagaaggc
    21721 tggattgaag tcgtggaata atttcaaagt aatgagttga aaaaaacgta aaaagaaaaa
    21781 atcaggaaga gactttaaaa agttttttcc tgatttttat atgttttact ttaaagaatg
    21841 caacaaaagt ttatgaaaga tggacacctt tgtcaacgta gataatatca ccgatgattc
    21901 cgctggaaag tgggctgatt aagaaagcac aagcattacc gacttcttcg atcgtcacac
    21961 cttgctgatc aggcgtacga gattcagata actggatcag tttttgatag tctttaacac
    22021 ctgtgacagc taatgttttg attgccccag ctgagattcc attgacccga attcctttag
    22081 gcgagaactc agctgccaaa taacggatag cagcttcaag agaagctttc gcaataccca
    22141 tcatgttata attcgggatt gcgcgttctg aacctagata agtcatgcta acgatcccgc
    22201 tgtttggtgc aagaaacggt tgtgcgtatt ttgatacagc aattaaagag tagctgctga
    22261 tatcttgagc taattgatag ccgtctctgg aaatatcaga cacatttccg gacaattctt
    22321 ctttgttggc gtaagcaact gcatggacaa ggccgtggat ctccccagca tattcaccga
    22381 tggcattcat tgctttttcg atgctttcgt cgctagaaac atcacattct acagtgaatg
    22441 cttcttcgcc gaccaatttg actaatgatt ttttcattcg ttcattttgg taagtataga
    22501 taatttctgc cccttgtttc aacattgctt cagcacaacc ccaagcaatg ctttttttgt
    22561 tagcgacgcc cataatgacg attttttttc cttctagaaa tgacataatg actctccttt
    22621 gtttctgata aaaatttgat agtcgtaaaa aaatagagaa taatagctaa aataacttct
    22681 tgatttctta attattagtc aaaatgtttt gattgtcaaa ctattttttc ttaaattaaa
    22741 aaaagattgc taaatattta ggaatatgat actttgatag tcaaagtaat gaaaatggca
    22801 attgcctgaa agaaggagtt taattatgtc ttacgtatta tctgctactg aagtaatgga
    22861 attgattcct aatcgttatc ctatttgtta tattgattat gtagatactt tagaaccagg
    22921 aaaaaagatc gttgcgacaa aaaatgtaac aatcaatgaa gattttttcc aaggtcactt
    22981 tcctgacaat ccagtgatgc cgggtgcgtt gattctagaa acactggcac aagcaggttc
    23041 gatacttatc ctaaaatcag aagagtttct aggaaaaaga gcttatatcg gtgggatcaa
    23101 taaggccaaa ttccgtcaaa aagttgttcc aggagatgtg ctgaaatgtc attttgaaat
    23161 caccaaaatg aagggatcag tcggtacagc gttatctgca gcatatgtag atgataaaaa
    23221 agtctgtgag tgcgagttca cgttcatcgt caaccaaaat gcttgactat aaaacctgat
    23281 atagcaaaac aaaaggaagc ttacttgctt tttatgtaaa aagaagacgc ctgaatccta
    23341 gcatacgttg tcatctatgc aggattcaga cgttattttt ttatttttgt tttgcttctt
    23401 gcagtatatt gattttatcg atttttactt cttcttttgg tttgtctgaa ctatctgttt
    23461 cgatatttgc aatagcatcc acgacatcca ttccttcaat cacttggccg aagacagtat
    23521 aatggccatc tagtgaagga taaccgccgt ttttataagc gtcgatgatt gcttgaggat
    23581 agtcgtcttt taaaagacca tcatgcatat catctgtatt ttgaacgata aagaactggc
    23641 tgccgttact gttaggatct tgtgagcgag ccatagataa cgcacctctt atattataaa
    23701 ggtggttgtt gatctctgtt tcaaatcctt ctccccaaat gctttcccct ccagtgccat
    23761 cgcctttagg atcgccacct tggatcatga aatctttgat gacgcgatgg aaagtcagtc
    23821 cgttgtagta accgtctttt gcatgtgtca taaagttttc aaccgctttt ggtgcgtgtt
    23881 cgggaaataa tttgattttg attgtgcctt tattcgtcac catttcgacc agatcttcat
    23941 tttcggcgac atctttcgtc aattgtggta attccaatgc gttcaaatcg acgctactgg
    24001 cagtcgtgct ttccgcagta gatgtacttt ttgaactttc tgtagacgaa ctagaagaag
    24061 tcgtgttgtt tgcagaacaa ccagcagcaa acagcaatgc tgctgctaaa ctaatactta
    24121 aaataacttt atttttcttc ataactgttc ctttccaatt tactattttg ttatctttaa
    24181 tgataacaaa atagagggaa aatacctact taaattattg gaatttatca tttattttaa
    24241 aagaaaaaga aaaggtgtag accatttact ttgtgtttgc tataatgtaa gtggatacaa
    24301 aaacgaaaag atgcaggagg aaatggtaat atgggaaaat taggaatctc gatttatcca
    24361 gaacggtcaa catttgaaaa ggacaaagcg tacttggatt tagctcataa gtatgggtat
    24421 aaacgggttt ttaccagttt gctgcagatc aatgatgata aagaaaaagt tctttcagaa
    24481 tttaaagaag tagttgatta cgcgaatagc ctaggcatgg aagtaatggt tgatatcaat
    24541 ccagcgttat ttgaacagtt ggagatttct tacgatgact tatctttttt ccataagatg
    24601 ggtgcctacg gggtccgctt agatatcgga ttcacaggag cagaagaagc aaaaatgacg
    24661 cgcaatcctt ttggtatcaa aatcgagatc aatatgagtt cgggcacgaa ttacgttgac
    24721 aacatcatga gttattcgcc aaacacggat aatttattag gttctcataa tttttatcct
    24781 catcgatact ctggtttagg atacgaacac tttgtttttt gttcagaaaa attcagaaaa
    24841 tataatttga atacgatggc attcgtcaat tcgcaatctg ctgagtttgg cccttggcct
    24901 acgcaagatg gcttgtgcac gctggaagac caccgagatc ttgaaattgc gacacaagtg
    24961 aagcatttaa tccttacagg attgattgat gatatttcta ttggaaatgc gtacgcaagt
    25021 gaagaagaat tgaaagaaat ggcagaagca tttaacgcgg attatccaac attgaaagta
    25081 gatacggaag aaggtattac agaaaacgaa cgaatctgct tgtttgataa ccttcatagt
    25141 tatcgagggg atcgctcaga atatatcctt cgttcaacga tgactcgtgt atactacaaa
    25201 gataaagatt tcccgcctca taatacgcga gatatgcatc atggggatgt actgattgac
    25261 aatgaagggt acggtcaata caaaggagaa acacaaatcg ccttgaagga tatgaaaaac
    25321 gacggacgtg tcaatgttgt aggaagaatc tccgatgacg aattattcct ccttgacttt
    25381 ttgaaaccat ggtcaagctt taaattaatt gaaaataaaa aatagataat tagttattgc
    25441 agaaataatc cgctagaaat agccagttat ttctgctttt ttattttgtt tttttatagg
    25501 ttatgatttg tcaaattaag ctagaataaa atgcttcttg tacatagctc aaaaatattt
    25561 cgattggtgt tctgtaattc aatgattttc ttggaatatg attacgttga ttgctgacac
    25621 tggaaataaa tgtctgattc actt
//
LOCUS       DAZKKZ010000043        24977 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.044, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000043 DAZKKZ010000000
VERSION     DAZKKZ010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 24977)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24977)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24977
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.044"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(45..2189)
                     /locus_tag="ACG8LA_001858"
     CDS             complement(45..2189)
                     /locus_tag="ACG8LA_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HFQ0204154.1"
                     /translation="MKNKKTIRLLAATWLIAPSVLSTNTVFAVDNQIADQTVTTDTTT
                     SSSATSETTDSFTEDPTGTTNSTTGSTEPTEIDPADPSENEKPAETYSLTIAPSLIGK
                     IQLTASTADSPEQQPLDITESGTVEGLLAETKVTYTITPAEGEQIASVAVNGAKEVNY
                     DAKTFTVGTNNLSITAEFKAGPDTSTEKPTDPSEEVPSTPDPETPNKPDVGNNNNNNG
                     SNNSNNNNNNSNSGNSSNQTNPSGSNNNGNTQREPNHPNNGSSNGGTNNASSRPNTAN
                     QSGIENPSSASSDFVVKSPIDAVLPTNTTNVQQAIVREAFKHLGKPYVWGAKGPNTFD
                     CSGLTYYVYMKATGHYIGGWTGEQQYAGTQIPVSQAQPGDLVFWGPSSGVTHHVGIYI
                     GNGQFIHAPQPGDKVRVTSISDFTPDFAVRVNLAGLPAASGSLTGGSSILDGLDGSFH
                     FSQNQTTDQFLKKIADDAQEIGQKEGIYASVMMAQAILESGSGNSLLSSEPNHNLFGI
                     KGSYKGSSVTFNTLEQDSSGQSYQIRAQFRKYPSYKESLEDYADLIKNGLTGNPDFYK
                     PTWKSETKDYKEATKYLEGRYATDRQYSQKLNAIIEAYDLTKYDEPKKEAATTEEANA
                     EILNMSKRFDVPIKWTTDGVPITGLEFSTIKRVNNASSIFRVASIWDLWNNFTARQIP
                     ETTTRTVKAATVPVLTLLSLDKSFWLDLPLKK"
     gene            complement(2546..3919)
                     /locus_tag="ACG8LA_001859"
     CDS             complement(2546..3919)
                     /locus_tag="ACG8LA_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFQ0204155.1"
                     /translation="METTMNPEQMVLSEQIHMLIEQLGGKDNIDSVLPCATRLRIKLK
                     KQPVANAEKLKQQIPSIKYFILLDRYAEIIMDQGLAPAYKELTRQIDHSAPKEKLNPI
                     EKLFGLISEIFTPIIPLFAGSGILKGLVVLATTIGWLSETSGTYHILSAASNAVFYFL
                     PIFLAFSAAKTFKVNGYIAAVIAAALIEPNLTSLLSDSGKAATDFLGIPVVLMQYTST
                     VMPAILGIFFYSFVEKFLKKYIRENMQLVFVPLLSLVITVPLTLMVFGPAGVYLGEGL
                     AAAITWMMDINGPISGAIIAGGWNILVIFGIQWAVNPVMISNISAYGFDRIVPLTGAA
                     NFGMAGAALGVFLRSKRSKTRSISGSAFASILLAGVTEPTVYGIAIPLKKPFVAACIG
                     AAAGGAVMGFAQVKAIAFVFGSLTTLPAFISGTFFWYLAGLAVSLVVAMITTLVSGFD
                     EDLMSYE"
     gene            complement(3919..4314)
                     /gene="rbsD"
                     /locus_tag="ACG8LA_001860"
     CDS             complement(3919..4314)
                     /gene="rbsD"
                     /locus_tag="ACG8LA_001860"
                     /EC_number="5.4.99.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016872 - intramolecular lyase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-ribose pyranase"
                     /protein_id="HFQ0204156.1"
                     /translation="MKKGKVINSDISRVIAQMGHFDKLSIGDAGMPVPFGTEKIDLAV
                     SNGLPSFLSVLENVLEELEVQSIELAEEIKTMNPEILEKIKLLLPDTPISFIPHEEMK
                     KELNNCHAFIRTGEMTPYANIILVSGVVF"
     gene            complement(4342..5259)
                     /gene="rbsK"
                     /locus_tag="ACG8LA_001861"
     CDS             complement(4342..5259)
                     /gene="rbsK"
                     /locus_tag="ACG8LA_001861"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004747 - ribokinase activity [Evidence
                     IEA];
                     GO_process: GO:0006014 - D-ribose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HFQ0204157.1"
                     /translation="MNTVTVIGSINMDTTLRLTNMPKPGETMHAHEIFHAGGGKGANQ
                     AVAAKRSGARTSFIGGVGADSEGQQLLDLLTKENIDTSGIAEIQGATTGQAMIMVDAA
                     GENSILIHAGANNAFHEQEVLKNKQLITNSDFIIAQFESSLDATILAFSIAKDAGKTT
                     ILNPAPARETIPTELLEKTDIIIPNETETEIITGIRVTDHNSLVAAAEKLHELGIGTV
                     IITLGSAGAFYHTEKEHGIVPAFKVDAVDTTAAGDTFIGALSSTLQPDLSNLKEAILY
                     GNLASSVAVQSYGAQPSIPYREALEQSAV"
     gene            complement(5367..6380)
                     /locus_tag="ACG8LA_001862"
     CDS             complement(5367..6380)
                     /locus_tag="ACG8LA_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HFQ0204158.1"
                     /translation="MVKKKITIKEVAKLSGVSITTVSLILNGNTEKFSPKTVQKVLAA
                     KEELGYQPDYFARQMITKETKTIGVLVPDITNPFFSTLMRGIEDILYKQNFVTILCNA
                     DSDHQKEIEYLAELTRRGVDGFIIATSAVSTDAINENLKKQGRPFIVLDQKKSEGFSD
                     AVRTDDFRGGYLAGMHLLSLGHQTIALVYPENPPENVHARIEGFKSALDVYQIPHDQL
                     ILLPTQFSKQGGYQITAELLDSAATGVFALNDELAFGLYRGLEEAGKSIPEDYSIIGY
                     DNIDMCEYIKPKLTTIAQPIFELGQTSAKLLLDRIQFPEKEWEEKRLPVRLEKRFSTA
                     PLK"
     gene            complement(6461..7060)
                     /locus_tag="ACG8LA_001863"
     CDS             complement(6461..7060)
                     /locus_tag="ACG8LA_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HFQ0204159.1"
                     /translation="MNDLKENMIFDLSKTAFVAIDMQKEIVNNGTLSPHTAASILTNN
                     DLLVRTLKRTAALKVLVNVDISTFPYLSQQTDMGGMTASVPPEFTDLLLKDSLKDTDN
                     MLTITKYNPSAFFGTSLDLQLRRRGIETIILSGVATTNGVYATALDAFQHGYHIVLAE
                     DACSDRDKESHQLFIKKIFPKTARVRSTKQIIEAIQQSK"
     gene            7246..7947
                     /locus_tag="ACG8LA_001864"
     CDS             7246..7947
                     /locus_tag="ACG8LA_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0204160.1"
                     /translation="MKYVEVKNEYKRYKMGETTITANDDISFSIEKGELVIILGPSGA
                     GKSTILNILGGMDTPDEGQIIIDDTDIAQFSDKQLTAYRRTDVGFVFQFYNLVPNLTA
                     KENVELATEVSPDALDPVEVLRQVGLAHRLNNFPSQLSGGEQQRVSIARALAKNPKLL
                     LCDEPTGALDFETGKQVLKLLQNASRQHGNTVLIITHNSALAPIADRVIHINDAKVRS
                     VELNDHPSSIDEIVW"
     gene            7957..10668
                     /locus_tag="ACG8LA_001865"
     CDS             7957..10668
                     /locus_tag="ACG8LA_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HFQ0204161.1"
                     /translation="MKTRTYLKAGFREIRQSKGRFIAIILIVMLGTLLFVGVKTAGPV
                     MQKTMDHYVGTAGLSDLQIVSTGGLTQKDIAQAEKIPDAKVETGKQIYYSNTGKNEVI
                     QIFSYNKNNKQNKLQLTDGKLPEKPNQLVLDEKAEDEGYKIGDIYQIDSDELKEKEYT
                     ITGFVRSPLFINNLERGYANVGNGSVDYFVYLPESVFKTDIYSVLYLDFTNVKNLNTY
                     SKAYKDKMEQNQEKAEKYLQDRPEERLEELKKSANEELEPAQQKIADGKAQTTQARTR
                     LEDAKKQLAQQSATIQQLPEAQRTIAVQTLSQQEAQLAEQERQLVEKERELASAEEEL
                     NRNAEKIENLTKPSYLYNERSENVGFQEFGDLSDRIAAIANVFPVFFFFIAALITFTT
                     MTRMVEENRREIGTLKALGYTKVEIAKKYAIYASLASGIGIVLGTILGTNLLPRIIFE
                     LSNERYDIGSALIFYDWPPILQAAAAFFIAAFGAAMIVLFKDLRERPAALLQPKAPKP
                     GKRIFLEYITPLWSRLSFNQKISYRNLFRYKSRMLMAIIGIAGCAGLMVAGVGLKDSL
                     SSVSAKQFGPIIDYQAIVTLDSSTEDSRQKAADMLQKQEKVNEILAIHTQTVELRKKG
                     HASQSLTVIVPSKTADLDRFIHLTDLEENPRSLPKTGIAITQKVAELFDLSTGDHISL
                     YDEDQKEWKVEVKEIVKNYLGSFIYMSPEYYASVTDQSMMDNAFLLRTDKMTTKEEEM
                     LSEKLLATDAVTNTSFMSKQIETQEESMANLDSVVLIFVVLSGLLAFIVLYNLTNINI
                     SERVRELSTIKVLGFFDKEVTMYIVRENIIFTLLGIIGGFGVGYILTDFILQQASMEN
                     VIFPLVITWWAYVLSAGLTIVFTVIVMIVTHFKLKHIDMIDALKSNE"
     gene            11119..12747
                     /gene="treC"
                     /locus_tag="ACG8LA_001866"
     CDS             11119..12747
                     /gene="treC"
                     /locus_tag="ACG8LA_001866"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008788 - alpha,alpha-phosphotrehalase
                     activity [Evidence IEA];
                     GO_process: GO:0005991 - trehalose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HFQ0204162.1"
                     /translation="MTFKDKVIYQIYPKSYKDSNGDGIGDLKGIKEKLPYLNDLGIDM
                     IWLNPIYPSPQKDNGYDISDYTAIDPIFGTMEEFEQLIAEAKKYRIEIMLDMVLNHVS
                     TEHEWFKKALAGDQHYQDFFILREEPTDWVSKFGGSAWSPFGDTGKYYLHLYDRTQAD
                     LNWRNQAVREELFKVVRFWMEKGVKGFRFDVINVIGKDEQLKNNKENDGKPEYTDKPI
                     THTYLKELNQATFGTDSTIITVGEMSSTTIENCILYTEPSREELSMVFNFHHLKVDYE
                     NGNKWSTPPFDFAELKRLFHTWGEKMSEGNGWNALFFNNHDQPRALNRFVAIDQYRKQ
                     GAEMLATMIHLNRGTPYIYMGEEIGMIDPDYSSISDYIDVESLNAYKLLLEQGFTEKE
                     AFRRIKAKSRDNSRTPMQWSDTEQAGFTTGKPWLKVGGKLEEINVEKELSSEDSILSY
                     YKKLIRLRKTYPIVAQGDYHAYEANHPEVYGFLRQFEGQQLLVLTNFYDKDTRIAIPE
                     GFTEANILIDNYSDTVLHQSLELKPYQAIALLKN"
     gene            complement(12807..13988)
                     /locus_tag="ACG8LA_001867"
     CDS             complement(12807..13988)
                     /locus_tag="ACG8LA_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HFQ0204163.1"
                     /translation="MKKETDTTNRLIRFLGGKTSYYVLGIVILLALIIYFFHQISFIF
                     KPVGIIIATILPPLLFALILYYLLEPVIKRLSKHLSRNLSVIIVYVIILFLLGLGSIW
                     LIPFLEEQAKTLISSLPDLFQDFQESLRQFLEKTPFADSFNQFFASIDDVTSDIAGFI
                     GNYWESGAQRISNIFSTVTAIFITLFTGPIVAFFLLRDPQKFYQSVLAIVPPAFRTDF
                     KNLTKIANQQLGSFLKGQIIASFILGAVYWVCFLLIGLEFASVLAISAGLLCIIPYIG
                     PFIAFFPGLIIAFQDSTFMAVKFVIVWFAVQLLHGDLVIPRVMGDRLQIHPITILIVL
                     LVMGDLMGIVGVIFGIPIYTLVKLLVTFIFRKFKQRYNKFYGDKGEYENSSFSEEDYF
                     K"
     gene            14240..15763
                     /locus_tag="ACG8LA_001868"
     CDS             14240..15763
                     /locus_tag="ACG8LA_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HFQ0204164.1"
                     /translation="MKRLIGILAMLVLAGMLTACGASGKAEDSKEKLSVMTTFYPMYD
                     FTKAIVGDEGEVELLIPAGTDSHDYEPSAKDMAKIQDTDIFVYNDENMETWVPAIQKT
                     LQEGNVHTIKATEGMLLLPGSEEGHDHDHEHGEEGHTHELDPHVWLAPSLAIKQVANI
                     RDQLIEAYPEKQEVWTKNAAAYTEKLQALHQLYQETFKQAKQRSFVTQHAAFNYLALE
                     YGLNQVSIAGLSSSEEPSAARIAELKHFVKEHGINYIYFEENAKDSIARTLANEAGVS
                     LEVLNPLEGLTNEQIENGENYLSIMEANLEALKKTTETENPLEDTLTPKKEKSVYNGY
                     FEDEDVQDRSLSDWAGTWQTVDTYVEDGTFDPVFEYKEKLNQDKTAQEYKEYYTKGYQ
                     TDIASIKISEKEMAFTFKNGTTKRSNYRYVGKEILTYEAGNRGVRYLFEAEDKESGAF
                     RYIQFSDHTIAPADSEHFHLYAGNESQEVLLKEMENWPTFYPDTMDGREIAQEMLLH"
     gene            complement(15832..16560)
                     /locus_tag="ACG8LA_001869"
     CDS             complement(15832..16560)
                     /locus_tag="ACG8LA_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytR/AlgR family response regulator
                     transcription factor"
                     /protein_id="HFQ0204165.1"
                     /translation="MIPIYICEDDPKQLEVLSTVIKNRIMIENLDSYVHISTSDPEEL
                     LNAAKIRTSSFGIYFLDIELEDSEMDGVAIGKLIRELDPLGKIIYVTSHTEMSMKILK
                     SNIEPTDYIVKEDLYDLKENVEHILSKIFEDFQMSQIQKDIFKIEFNDEIKFLPIKDI
                     QYFSTSLGAPHKLEVHLTHAQLQFYEKIKEIEKMHRNFIRCHKSYVINTQNVRSINKK
                     TREVTLANGETIPASIRGLKKLIS"
     gene            complement(16573..17853)
                     /locus_tag="ACG8LA_001870"
     CDS             complement(16573..17853)
                     /locus_tag="ACG8LA_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HFQ0204166.1"
                     /translation="MFLWSIALQYLIYTICILLIDHHIRYKYLFAGVILISCILIGWV
                     YSILGIFTALIAIGMLMLTFFFFSTSRQQLVYALPFGLLTSLLGDHLTSIGDFFVLKS
                     SVIEPGDSLQYFHIVLSAFLSALLAFCLKKSLETWFHTVDRRMIGTIGTLILFTYYII
                     IFYTRFSGETPDVLALNTSFFILYLCVGLIILVYYWKISNKKLADQLLEQQVRMQQDY
                     IKDLEKNYQDLREFKHDYQNLLFSLHSYISEGDLEGLRSYYDQTILPTRQMMNLFPAN
                     LSMLDNMKVPEIRSLLSLKLMMAQEKGLIVQLHFPEPIELDTKHTVNLVRMLGIILDN
                     AIEGASAAKKKKIELTILKKNHSVMIRVINTTTNTLPLNQLKQKGFSTKTNPKNEGLG
                     LFILDELTKTNPYLFLETSIENQRFSQTIYIQIK"
     gene            complement(17994..18596)
                     /locus_tag="ACG8LA_001871"
     CDS             complement(17994..18596)
                     /locus_tag="ACG8LA_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0009372 - quorum sensing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HFQ0204167.1"
                     /translation="MKDKVVNKLLEALFSGDKSEEDMVYVQVKFVLEVLLNNLGKLAV
                     VLVFSLVTGSWAETGITFLSYICIRRYAYGLHSDSEFVCLLWTLLYLWGVPLVMKHLQ
                     LTISFPMMVFLLISCFLLLLRYGSRGTAINPIEPEKRPPLLKKAISMFLIFSLITLFF
                     SASYFSTYLLLGIVLEIATLLPITNYLMNFGGIFHEKNNH"
     gene            18841..19047
                     /locus_tag="ACG8LA_001872"
     CDS             18841..19047
                     /locus_tag="ACG8LA_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204168.1"
                     /translation="MENEQLFEVGETYAFKSDLFESPIKGKIEKIYENSVMIRVMKCA
                     VEDNDTAHNLHWQLVVRKSSTIEE"
     gene            19359..20078
                     /locus_tag="ACG8LA_001873"
     CDS             19359..20078
                     /locus_tag="ACG8LA_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HFQ0204169.1"
                     /translation="MPIIVIIVAGTIGAGKSTLTEMLAQDLETKPFYENVEDNEVLPL
                     FYSNPEKYTFLLQIFFLNKRFLAIKDAFSHDDNVLDRSIYEDSMLFHLNADLGRVSEV
                     EVKQYEGLLETMLKELEEISPQKKPDLLVYIRVSFETMLARIKKRGREYEQLEQDPEL
                     YSYYKELNRRYEEWYEQFDICPKIVIDGDKYDFVADPACGEQIVQEIKMRAKKMTEEA
                     DAQSIRYTTNNPKAKGIFTTK"
     gene            complement(20159..20842)
                     /locus_tag="ACG8LA_001874"
     CDS             complement(20159..20842)
                     /locus_tag="ACG8LA_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YoaK family protein"
                     /protein_id="HFQ0204170.1"
                     /translation="MQTSFHEGRTIGLLLTFIGGAMDSYTYIQYGAFASAQTGNIILS
                     IIQAFDGEWLSVGKKVLSTLFFFLGILLTKYLIDYFRKKEKHFWRLFVLYYEAVIFFF
                     VSLTPVHEHPALVTILIAFTASIQWVAFDKINGRAYTNLFTTGNLKGVATNLYDYCIS
                     KEKADFDRFFHYLSVVLAFIAGAIVLVFCHHLFGAHSILIVSILFLIMALTQTFHLWQ
                     FYHTNRFTI"
     gene            21060..23246
                     /locus_tag="ACG8LA_001875"
     CDS             21060..23246
                     /locus_tag="ACG8LA_001875"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HFQ0204171.1"
                     /translation="MNEKEILRLQKELKRWENKYKKLQQVFRLQEEIIATYEAAYGEA
                     PGLIEEEVQVKESEGNSSFFKMMEKRSYNRFNQEQKAAITYDMKKHLRIIAGAGSGKT
                     QTICAKAVYLMTQKQVDEERILMITFTRNAANELKKRVDNFSQRKTAVHIGTFHSIFF
                     RIYNEICRKFPEVAMQGIQGDFSKDTAQKVNAVLQQLIRKYNLYIFDQYGEKTIASRL
                     DYWQNMNLSVEEMVQLVKEKYDSIDKNARQPISERLYGLLTELQEQKRSQQLLEFNDV
                     LQNLKSALENEEIQHYIGQKYDYLFIDEFQDTNPLQWEIVKRMTKENRIKLIVVGDDD
                     QSIYGFRGSEPAYIKNFEKEYPTKTLFLLTNYRSRAAIVQGANRLISYNKNDRIPKAM
                     IPAQKEAGVMEAYLFSDTKAESQWLIKQIQTFIQKNGKYKESIILYRSASQTQQLVQS
                     LLKTNIPFVLEADSPYEGIFGIKSFQHFYQKIVHWQTALNLQKKNQAYQQLLRQLMAD
                     CYLKKSECDQYFSPKYQNIAVADYILSISPNLKSKSAEIREFEEALRKTDQHQEIYSL
                     VQSYLHLPRIAKEIDQSDQEWIREEVKQHATFRRLQALSQETQATAKELKTRLIAYRQ
                     GKLDALCIQSIHKSKGLSYRNVFLIGCNEGSLPYNGATEKKVIDFNEIKAEPVTTIEE
                     ERRLFYVAMTRARNRLYLCVPQMKNSRKLKVSRFIKETGSRVKKGK"
     gene            23592..24002
                     /locus_tag="ACG8LA_001876"
     CDS             23592..24002
                     /locus_tag="ACG8LA_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HFQ0204172.1"
                     /translation="MIKVYTSPSCTSCRKARAWLQANQLEFEEKNIFAEPLTESEIKK
                     ILAATEGGVQDIISTRSKIYEKLGIDFNELTLKQMIVLFKEYPSLLRRPILIDEKRIL
                     IGFNEDEIRSFVPREIRCVARNLIYLQNNNILNS"
     gene            24016..24372
                     /locus_tag="ACG8LA_001877"
     CDS             24016..24372
                     /locus_tag="ACG8LA_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HFQ0204173.1"
                     /translation="MEVKVYGSAHCVTSLKAKQWLEHHQLPYQFVDLEERDLSTEEAE
                     ELCSFEEVQAEQLFATWSEAFHNIAIDLSCVGKKQLIFLCTQHTNLLRRPLIIIDEVL
                     FIGYNEQLMEQLILNK"
BASE COUNT         8368 a         4437 c         4872 g         7300 t
ORIGIN      
        1 taaaaaggga gtgtgacagt gtcacatccc ctttttaatt tattctattt ctttaaaggc
       61 agatcaagcc agaatgattt gtctaaactt aacaaggtta gtacaggaac agttgcagct
      121 ttaactgtac gagtagttgt ttctggtatc tgtcttgccg taaaattgtt ccacaaatcc
      181 cagattgaag cgacacggaa gatggaagaa gcgttgttga cgcgttttat cgttgaaaat
      241 tctaatcctg tgattggcac gccatctgtt gtccatttga ttggcacatc gaatcgctta
      301 gacatattga ggatttcagc gtttgcttct tcagttgttg ctgcttcttt tttcggttca
      361 tcatattttg tcaggtcgta cgcttcgatg atcgcgttca atttttgtga atattggcga
      421 tctgtagcat aacgtccttc caaatatttg gttgcttctt tgtagtcttt tgtttccgac
      481 ttccaagttg gtttgtagaa atcaggattg ccagtcagtc catttttgat caagtcggca
      541 tagtcttcca aactttcctt gtaagaagga tatttacgga attgtgcgcg gatttggtag
      601 ctttgtccgg aactatcttg ttcaagtgta ttgaaggtca cgctgcttcc tttatatgat
      661 cctttgatac caaaaaggtt atgatttggt tcgcttgata ataagctgtt tccagatcca
      721 ctttcaagga tagcttgagc catcatgact gatgcgtaga ttccttcttt ttgcccgatt
      781 tcctgtgcat catctgcaat ctttttcaag aactgatcag ttgtttggtt ttgactgaaa
      841 tggaacgagc catctaatcc atctaaaata gatgagccgc ctgtcagcga acctgaagca
      901 gcaggtaaac ctgctaagtt tactcggaca gcaaaatcag gcgtgaaatc tgaaatagaa
      961 gttactcgaa ctttatctcc tggttgaggc gcatggataa attgtccgtt cccaatatag
     1021 atacctacat ggtgagtaac accggaagaa ggtccccaga agacgaggtc gccaggttgg
     1081 gcctgactta ctggaatctg cgtacctgca tattgctgtt cgcctgtcca gccaccgata
     1141 taatgaccgg ttgctttcat atatacgtaa taagtcaaac cagaacagtc aaaagtattt
     1201 ggaccttttg ctccccatac atatggtttt ccaagatgct tgaatgcttc tcgaacgatt
     1261 gcttgttgga cattcgttgt atttgtaggc aatacagcat caattggtga ttttacaaca
     1321 aaatcagaag aagcagaaga tggattctct ataccgcttt gatttgctgt atttggacga
     1381 gatgaagcat tgttcgttcc gccattcgat gaaccattgt ttggatggtt tggttctctc
     1441 tgagtatttc cattgttatt cgatccagat gggtttgttt gattcgaaga attcccgctg
     1501 ttcgaattat tgttattatt gtttgaatta tttgaaccat tattattgtt gttattaccc
     1561 acatctggtt tgtttggcgt ttccggatct ggtgtactag ggacttcttc actaggatca
     1621 gttggtttct ctgttgaagt atccggtcca gctttaaatt ctgcagtaat agataaattg
     1681 ttcgtaccta ctgtaaaggt ctttgcatca taatttactt ctttggcacc attaacagcg
     1741 actgaagcaa tttgttcacc ttcagctggc gtaatagtgt aagttacctt cgtttccgct
     1801 aataaacctt ctaccgttcc actttccgta atatccaaag gttgctgttc aggggaatcc
     1861 gctgtcgaag cagtcagttg gatcttacca atcaaagaag gagcaattgt aagggaatat
     1921 gtctcggctg gcttttcatt ttctgatgga tcagccggat caatttcagt tggctcggtc
     1981 gatcctgttg ttgagttagt tgttccagtt gggtcttctg taaaagaatc cgttgtttca
     2041 ctagtagctg agctggatgt agtcgtatct gttgtgactg tttgatcagc tatttgatta
     2101 tctacggcaa atacggtatt ggtcgacaaa acagacggag caatcagcca agtagcagct
     2161 agcaaacgta tcgttttttt atttttcata ataaactagt ccttttcctt tcattgattt
     2221 tctgtcttat tcagcattca ttagacattt tttggaacag ataatcgtgt cgaaaagctt
     2281 tttcttttca taaatctgtc tgtgtattct aaataaaaca atttgtaaat aagcaacgag
     2341 cattcattcg tttttctttg acgttcattt tattgcatag accacctttg tttggggata
     2401 aacaagtggg gataaaaatg gttatgcata tgtaaattat accaaagttt ggaaagtatc
     2461 acaaaaattt ataaaaataa tgatcctaaa aagaaaaaga ctgaaatatg tgataaacat
     2521 ctcatacttc agtctttttc attaactatt cataagacat taggtcttca tcaaacccgc
     2581 taacgagagt agtgatcatt gctacgacta gactaacagc cagtcctgct aagtaccaga
     2641 aaaaagtacc ggaaatgaat gcaggcaatg tggtcagact accaaataca aaagcgatcg
     2701 ctttcacttg ggcaaatccc attacagctc caccagcagc tgcaccaatg caagcagcaa
     2761 caaatggttt tttcaatggg atcgcaattc cgtaaacagt tggttcggtc actcccgcaa
     2821 gtaaaatcga agcaaaagca gaaccggaga tcgaacgggt ttttgaacgt ttacttcgca
     2881 gaaatacacc taaagctgca ccagccattc caaaattggc tgctcctgtc aacggaacga
     2941 ttcggtcgaa cccataagca gagatattac tgatcatgac agggtttaca gcccattgga
     3001 taccaaatat taccaaaata ttccaaccac cagcgatgat tgcgccactg atcggtccgt
     3061 taatatccat catccaagta attgcggcag ctaaaccttc gccaaggtaa acacccgcag
     3121 gcccgaatac cattaacgtc aaaggaaccg tgataactaa tgaaagtaaa ggtacaaata
     3181 ctaattgcat attttcgcga atatattttt tgaggaattt ttcaacaaaa gaataaaaga
     3241 aaatacctaa aatcgccggc atgacagtag acgtatactg catcagtact acaggaatcc
     3301 ccagaaaatc agtagctgct ttgccactgt ctgaaagtaa agaggtcaga ttcggttcaa
     3361 tcagtgctgc agcaatgaca gccgcaatat atccattcac tttaaacgtt ttggcagcag
     3421 aaaaagcaag aaagattggc agaaaataaa agacggcatt cgacgcagca gacaaaatat
     3481 gataagttcc gcttgtttca ctaagccagc caatcgtagt cgctaaaaca accagacctt
     3541 ttaatatacc agaaccggca aacagcggaa tgatcggcgt aaagatttcc gatatcaaac
     3601 caaatagttt ttcgatcgga tttagctttt ctttcggagc tgaatgatcg atttgacgcg
     3661 tcaattcctt gtaagcagga gccaatccct gatccatgat tatttctgca tatctatcga
     3721 gtaaaatgaa atacttaatg gaagggattt gctgttttaa tttttctgca ttggctactg
     3781 gctgtttttt caatttgata cgaagccgag tcgcacatgg aaggacagaa tcaatattgt
     3841 cttttcctcc caactgttca atcagcatat gaatctgctc ggacagtacc atctgttcag
     3901 gattcattgt cgtttccatt agaagaccac tccactcact aatataatat tggcgtaagg
     3961 tgtcatttcg cctgtacgaa taaatgcatg acagttattc aactcttttt tcatttcttc
     4021 atgtgggata aagctaatcg gtgtatctgg taacaataat ttgatttttt ccaatatttc
     4081 cgggttcatt gtctttattt cttccgccaa ttcaatcgat tgtacctcaa gttcttctaa
     4141 aacgttttct aaaacagata aaaaacttgg aagaccgttt gagacagcca aatctatttt
     4201 ttcagtacca aaggggacag gcatgcctgc atccccgata cttaatttat caaagtgccc
     4261 catttgtgcg attactcgtg aaatatctga attgattact tttccttttt tcatgtttgt
     4321 ttcttcctct cattgttaat tttagactgc tgattgttct aaagcttcgc ggtaagggat
     4381 agaaggttgc gcaccataag actgcacagc aacagaagag gctagatttc cataaaggat
     4441 cgcttctttc aagttactaa ggtctggctg aagtgtgctg cttaatgcgc caataaatgt
     4501 atcacctgcg gctgttgtgt caacggcatc cactttaaaa gcagggacga taccgtgttc
     4561 tttttctgta tgatagaaag cgccggcact gcctagtgta atgattactg ttccaatacc
     4621 taattcatgg agtttttcgg ctgctgcgac caaactgtta tgatctgtca ctctgattcc
     4681 tgtaatgatt tctgtttctg tttcatttgg tataatgata tctgtctttt caagtagttc
     4741 agtaggaatc gtttcacgag ctggtgcagg attcaggatc gttgtttttc ctgcgtcttt
     4801 tgcaatagaa aaagctagga tcgtcgcatc taagctactt tcaaactgag caataataaa
     4861 gtcactgttt gtaatcagtt gcttgttttt taggacttct tgttcatgga aagcattatt
     4921 tgcccctgca tggatcaaga tactattttc tcctgctgcg tctaccataa tcattgcttg
     4981 tccggttgtg gcgccttgga tttcagctat cccagatgta tcgatgtttt cttttgtcag
     5041 tagatctaat aactgttgtc cttcgctgtc agccccaacg cctccaataa aagatgtccg
     5101 tgcgcctgaa cgtttggctg ccactgcttg gttggcacct ttacctccgc cagcgtgaaa
     5161 aatctcatgc gcatgcatcg tttcgcctgg cttgggcatg ttggttaaac gaagggtagt
     5221 gtccatatta atacttccaa ttactgtaac cgtgttcatt ttacaaacct ccaactatct
     5281 catttatttt gatgggaaaa ttatttttta aaacgtttta gtaaaacgtt ttaatagttc
     5341 gataaaaata tagcacacct tgaaagctat ttcaagggtg cagttgaaaa tcttttttct
     5401 aatcgtacag gtaatctttt ttcttcccat tctttttctg ggaattggat ccgatctaac
     5461 aataacttgg cagatgtttg tcccaattcg aagattggtt gtgcgatcgt tgtcagtttc
     5521 ggcttgatat actcgcacat atctatatta tcatagccaa taatgctgta gtcttcaggg
     5581 atgctttttc cagcttcctc taatccgcga tataatccaa aagctaattc atcatttaaa
     5641 gcaaacacac cagttgcagc agaatcaaga agttctgctg tgatctggta gccaccttgt
     5701 tttgagaact gtgtaggtaa gaggatcagt tggtcgtgag ggatttggta aacatcaaga
     5761 gcagatttaa acccctcaat ccgagcgtgg acattttccg gtggattttc aggatagaca
     5821 agggcgatcg tttgatgtcc tagactaagc aagtgcatgc ccgctaggta accaccgcga
     5881 aaatcgtctg ttcgtacggc atcactaaat ccttcagatt ttttctgatc caaaacaatg
     5941 aagggccggc cttgtttttt caaattttcg ttgattgcat ctgtagagac agcagaagtc
     6001 gcgataatga atccatccac acctcgacgt gtgagctcgg ctagatattc gatttctttt
     6061 tgatgatcag aatcagcatt acataatatc gtgacgaaat tctgcttata caagatatcc
     6121 tcaattcctc gcatcagtgt actgaagaat ggattcgtga tatcaggaac gagtacacca
     6181 attgttttcg tttccttggt aatcatttgt ctagcaaaat agtcaggctg atagcctaat
     6241 tcttctttgg cagctaaaac tttctgaaca gttttcggac tgaatttctc cgtatttcca
     6301 tttaatatca aggagacagt tgtgattgaa acgccggaaa gtttagcgac ttctttgatt
     6361 gtgatctttt ttttcaccat gttcatactc ctatctaaat cctgtggtta ttttcccatg
     6421 aaatcaaaaa gaagtaaatg aaaatcacgt gtgccagtac ttatttgctt tgttggatag
     6481 cttcgattat ttgtttcgtt gagcgtactc gtgcagtttt cggaaatatc ttttttatga
     6541 acaattgatg ggattctttg tcacgatcac tgcaagcatc ttcagcaagc acgatatggt
     6601 acccgtgttg aaaggcatct aatgcagtag catatacacc gtttgttgtc gctacaccgc
     6661 ttaaaatgat agtttcgatt ccacgccggc gaagttgaag atcaagagaa gtaccaaaaa
     6721 aagcacttgg attgtatttt gtgatagtca acatattatc tgtatctttc aaagaatcct
     6781 tcaaaagtaa atcagtgaat tctggaggta cagaagcagt cattccaccc atatcagttt
     6841 gttgactcaa ataagggaaa gtggagatgt ctacgttcac taaaactttc aaggcagcgg
     6901 tacgtttcaa tgttcttact aacaaatcat tgtttgtcag aatagatgct gcagtgtgtg
     6961 gagagagtgt accgttattt acgatctctt tttgcatgtc gatcgcgaca aaagcagttt
     7021 ttgataaatc aaaaatcata ttttccttta aatcattcat gatgttcctt ctttcaaata
     7081 acaatgtttt ttatgtaagt aaatcataaa tcgtttattt gtcaactaaa ttaaaggatt
     7141 cctttcttta gtctagagaa attcagtggt aaaataaata agtgtgagaa aacgcattcg
     7201 atgcatagat atagcgagaa atatcgtgaa aatggaggaa tcagagtgaa gtatgtcgaa
     7261 gtaaaaaatg aatacaaacg atacaaaatg ggagaaacga ccattacagc aaatgacgat
     7321 atttcttttt caattgaaaa aggcgaatta gtgattatac ttggtccaag tggagcagga
     7381 aagtcaacga ttcttaatat tttaggtggg atggatacac ctgatgaagg tcagatcatt
     7441 attgatgaca cagatattgc gcaattttca gataaacagc ttactgctta ccgacgaaca
     7501 gatgtagggt tcgttttcca attctacaat ctcgttccta atctaacagc aaaagaaaat
     7561 gtggaattgg caacggaagt ttctcctgat gcgcttgatc ctgtagaggt attgaggcaa
     7621 gtgggcctag ctcatcgatt gaataacttt ccgtcccaat tatcaggagg cgaacagcag
     7681 agggtttcaa ttgctcgtgc actagctaaa aatcccaaac ttcttttatg tgatgaaccg
     7741 acaggcgcgc tggattttga aacgggcaag caagtattga aattattgca aaacgctagc
     7801 agacaacacg gcaataccgt tttgatcatt acacataatt ctgctttagc gcccatcgct
     7861 gatagagtca ttcacattaa tgatgctaaa gtaaggtctg ttgaattaaa tgatcatcct
     7921 tcatccattg atgagattgt atggtagggg gattttatga aaacaagaac atatcttaaa
     7981 gcaggttttc gcgaaattcg gcaatctaaa ggacgattca ttgcaatcat ccttattgtc
     8041 atgctaggaa cacttttatt tgtaggtgtc aaaactgctg gacctgtcat gcaaaaaacg
     8101 atggatcact atgttggtac agcaggactt tctgatttgc aaatcgtttc tactggtggc
     8161 ttgacacaaa aagatattgc tcaagcagaa aagatcccag atgcaaaagt agaaacagga
     8221 aaacagatct attattccaa tactggcaaa aacgaagtga ttcaaatatt ttcttataac
     8281 aaaaataaca agcagaacaa gctacaatta actgatggaa aactcccgga aaaaccaaac
     8341 cagcttgtat tggatgaaaa agcggaagat gaagggtata aaatcggtga tatttatcag
     8401 attgattcag atgaattgaa agaaaaagag tataccatca cgggctttgt ccgttctcca
     8461 ttgttcatca acaatttgga gagaggatac gcgaacgtcg gaaatggtag cgtcgattat
     8521 tttgtctatt tacctgaatc cgtttttaaa acagatattt attctgtctt atatcttgat
     8581 tttacaaacg taaagaattt gaatacgtac agcaaagctt acaaagataa aatggagcaa
     8641 aatcaagaaa aggcagaaaa gtatttacaa gatcgacccg aagaacgctt agaagagctg
     8701 aaaaaatcgg ccaacgaaga attagaaccg gcacagcaaa aaatagcgga tggcaaagca
     8761 caaacaacgc aagcaagaac acggttagaa gatgctaaaa aacagttagc gcaacagtca
     8821 gcaactatcc agcagcttcc tgaagcgcaa cgaacaatcg ctgttcaaac attatctcaa
     8881 caagaagctc aacttgctga acaagaaagg caattagttg agaaagaacg tgaactggcc
     8941 tctgcagagg aagaattgaa tcgaaatgca gaaaaaattg aaaatttaac taaaccatca
     9001 tacctataca atgaacgttc agaaaatgtc ggttttcaag aatttggtga tctgtctgat
     9061 cgtatcgctg cgattgccaa tgtttttcct gttttctttt tctttattgc cgcattgatc
     9121 acctttacga caatgacacg tatggtagaa gaaaaccgca gggaaatcgg gacattaaag
     9181 gcgttaggtt atacgaaagt tgaaatcgca aaaaaatatg caatctatgc aagtctagcc
     9241 tcagggatag gtattgtttt aggaacgata ttaggaacga atcttttgcc aaggatcatt
     9301 tttgagctgt ctaacgagcg gtatgatatt gggagtgcgc ttatttttta tgactggccg
     9361 ccgattttac aagcagctgc cgcattcttc attgccgcat ttggcgctgc aatgatcgtt
     9421 ttattcaaag atttaagaga acggcctgct gcattgcttc aaccgaaagc accgaagcca
     9481 gggaaacgca tttttcttga atacatcact ccgctgtggt cacgccttag ctttaatcaa
     9541 aaaatcagtt accgaaatct cttccgatat aagtcaagaa tgcttatggc gattatcgga
     9601 attgctggat gtgccgggct gatggttgca ggcgtgggat tgaaagattc tctaagttct
     9661 gtttcagcca aacaatttgg accgatcatt gactatcaag caatcgttac attggattca
     9721 tccacggaag atagtcgtca aaaagcagcg gatatgctgc agaagcaaga aaaagtaaat
     9781 gagatcctag ctattcatac tcaaaccgta gaattgagaa aaaaaggaca tgcttcgcaa
     9841 agtctgacag tgatcgtacc aagtaaaaca gctgatttgg atcgttttat ccatttaact
     9901 gatcttgaag agaacccacg ctccttgcct aaaacaggaa tcgctattac gcaaaaagta
     9961 gcagaactat ttgacttatc tacaggagat catatttcgc tttatgatga agatcaaaaa
    10021 gaatggaaag tcgaagtaaa agaaatcgtg aaaaactatc taggtagctt tatttatatg
    10081 tcccctgaat attatgcttc agttactgat caatcgatga tggataatgc atttttgctg
    10141 cgtacagata agatgacaac aaaagaagaa gaaatgcttt ccgagaaact gcttgccaca
    10201 gacgctgtga caaatacgtc tttcatgtcc aaacaaatcg aaacgcaaga agaatcaatg
    10261 gcgaacttag actcggttgt cttaatcttt gtcgtattat caggactgct ggcttttatc
    10321 gtcttgtata atctaactaa tatcaatatt tccgagcgtg tacgcgaatt atctacaata
    10381 aaagtccttg gattttttga taaagaagtc acgatgtaca ttgttcgaga aaatatcatc
    10441 tttactcttt taggaatcat cggaggattt ggtgtaggat atatattgac tgacttcatc
    10501 ttgcaacaag cgtctatgga gaatgtcatc tttccattag tgatcacatg gtgggcttat
    10561 gtcttatcag caggattaac tatcgtattt acggttattg tgatgattgt tacccatttc
    10621 aaattaaagc atatcgatat gattgatgcg ttgaaatcga atgaataaaa acagaggttg
    10681 tgaaatcagc ggtttgacct gagtattaga gaaacaaacg gcaaaatagt ttttcatatt
    10741 ttgccgtttt ttgagctaat accgaaggac agctgattga acaccatgaa tcagaggttg
    10801 taaaaaagcc gtcctgcatc gagcaaaaag aatactcaaa taaaattagc tcctcatgtt
    10861 ttacatttga gaagactgat tgccgtagat aaaagctttt gaacaccatt tatagaagaa
    10921 acaagaatat tttgctattt taaacaagag gatagacaaa tacatgtctg atctcttgtt
    10981 ttttattggg caacagacct cttagaatgt ataaagataa attttacaaa cgctttcggt
    11041 tcagttataa taataaatga taacttgtat atataagttg tggtaggtaa taaatcagtt
    11101 gaatggaggt aaatatccat gacatttaaa gacaaagtca tttaccaaat ctatcccaaa
    11161 tcttacaaag acagtaatgg tgatggaatt ggagatttaa aaggaatcaa agaaaaactc
    11221 ccgtatctga atgatctagg catcgacatg atttggctaa accctattta tccaagccct
    11281 caaaaagaca acggttatga tatctctgat tacacagcca tcgatcctat ctttggtacg
    11341 atggaggaat tcgaacagct aatagccgaa gcaaagaaat accggataga aatcatgctc
    11401 gatatggtgc tgaatcacgt ttcgacagaa catgaatggt tcaaaaaagc actagcaggg
    11461 gaccagcatt atcaggactt cttcatttta agagaagagc caacggattg ggtatcaaaa
    11521 tttggtggaa gtgcttggtc gccatttgga gatacgggga aatattattt gcacttatat
    11581 gatcggacac aagctgactt gaactggcgg aaccaagcag taagagagga actattcaaa
    11641 gttgttcgtt tttggatgga aaaaggggta aaaggattcc gtttcgatgt tatcaatgtt
    11701 atcggtaaag acgaacaatt gaaaaataat aaagaaaatg atggcaaacc tgaatatacg
    11761 gacaaaccaa tcacccatac gtatctaaaa gaattgaacc aagcaacgtt tgggacggat
    11821 tccactatca tcacagtcgg tgaaatgagc tctacgacga tcgaaaattg tatcttgtat
    11881 acagaaccta gtagagaaga attatcaatg gtctttaatt tccatcattt gaaagtcgat
    11941 tatgaaaatg ggaataaatg gtctactcct ccatttgatt ttgcagaatt aaagcgacta
    12001 tttcatacat ggggagaaaa gatgagtgag ggtaacggct ggaatgctct attttttaat
    12061 aatcatgatc agccacgtgc gctcaatcga tttgtagcta tcgatcagta tcgaaaacaa
    12121 ggagcagaga tgctagcaac catgatccat ttgaaccgtg ggacgcccta tatttatatg
    12181 ggagaagaaa tcggcatgat cgacccagac tattcatcga tttccgacta tattgacgta
    12241 gaaagtttga atgcttataa gttactcctt gaacaaggat tcacagaaaa agaagcgttt
    12301 cgtcggatca aagcaaaatc tcgcgataac tctcgaacac ccatgcaatg gtcagacaca
    12361 gaacaagcag gatttactac agggaaacct tggttaaaag ttggaggcaa gctagaagag
    12421 attaatgtag aaaaagaact atcttctgaa gattctattt tgtcctatta caagaaattg
    12481 attcggctga gaaaaacata tccaatcgtt gcacaaggag attatcatgc ttatgaagca
    12541 aatcatccgg aagtttatgg ctttcttcgc caatttgaag gacagcagct gcttgtatta
    12601 acaaatttct atgataaaga tacaaggatc gccatcccag aaggattcac agaagccaat
    12661 attcttatcg ataattattc cgatactgtt cttcatcaaa gtctggagct aaaaccatac
    12721 caggcaattg ctttgctgaa aaattaaaac aaaaacacaa aacgtcgttc ctacgagcta
    12781 ttctcgtaag atcgacgttt tgtgttttat ttaaaataat cttcttcaga aaatgaagag
    12841 ttttcatact ctcctttatc gccataaaat ttattgtagc gttgtttgaa tttacggaaa
    12901 ataaaagtaa cgagtaattt gactaacgta tagataggaa taccaaaaat aacgcccaca
    12961 attcccatta gatcacccat gacaagtaaa acgattaaga tcgtaatcgg atggatctgt
    13021 aaacgatcac ccattactcg aggaatcacc aagtcaccgt ggagaagttg tacggcaaac
    13081 cagacaatga caaatttgac agccataaaa gtagagtctt ggaatgcaat gatcaaacct
    13141 ggaaagaagg cgataaacgg cccaatatat ggaatgatac ataacaaccc agcagaaata
    13201 gctaaaacac tagcaaattc taatccgatc agtaagaaac aaacccagta gactgctcca
    13261 aggataaatg aagcaatgat ttgccccttt agaaatgaac ccaattgttg attagcaatc
    13321 tttgtcaaat ttttaaaatc tgtacgaaat gctggtggga caatcgctaa aactgactga
    13381 taaaattttt gaggatctct caaaaggaaa aaagcgacaa ttggaccagt aaataaagta
    13441 ataaaaatag ctgtaacagt tgaaaaaatg ttgctgatcc gttgtgcgcc actttcccaa
    13501 taatttccaa taaatccagc tatatcagac gtcacgtcgt caatagaagc gaaaaattga
    13561 ttaaatgaat cggcaaaagg tgttttctcc aaaaattgtc ggagactctc ttgaaaatct
    13621 tgaaacaaat ctggcaaact actgatcaat gtctttgcct gttcttcaag aaaaggaata
    13681 agccatatgc ttccaagccc caataaaaat aaaataatca cataaacgat aatgactgac
    13741 aagttcctcg aaaggtgctt gctcaaacgt ttgatgactg gttccaaaag ataatacaag
    13801 atcagtgcaa acaataatgg gggcaagata gtagcgataa tgattccgac aggcttgaat
    13861 ataaacgaga tctgatggaa aaaataaatg atcagcgcaa gtaagataac tattcctaaa
    13921 acatagtaag aggtttttcc tcctaaaaag cggatcaaac gattcgttgt atctgtttct
    13981 tttttcactc tttttcctcc tttatctata acttcattat agacaaaagc gggtataaaa
    14041 ggaaaatgat agaggttgat tgcaaaaata tcgtcaatca ttcatataaa ctttctcatc
    14101 aattaaaata agaaaacgct tgacagttct tttaaccata tgataaatta aatcctgttg
    14161 ctaaaacgta actattacgg tttgcgaaaa gcgaatcgga acattcaaat gaaagaagat
    14221 gagaagagga gtgtcataaa tgaaacgatt gataggtata ttggccatgc tggttttagc
    14281 aggtatgtta actgcttgcg gggcaagtgg gaaagccgag gacagtaaag aaaaattgag
    14341 cgtgatgacg accttttatc ccatgtatga ttttacaaaa gcaatcgtcg gggatgaagg
    14401 agaagtagag ttattgattc cagcagggac tgattcccac gattatgaac cttctgctaa
    14461 agacatggca aagatccaag atacagatat ctttgtttat aatgatgaaa acatggaaac
    14521 atgggtcccc gcaatccaaa aaacattaca agaaggcaat gtccatacga taaaagcgac
    14581 agaaggtatg cttttacttc cgggaagtga agaaggacat gatcatgacc atgaacacgg
    14641 ggaagaaggc catacacatg agctagaccc acatgtatgg ctagctccaa gtttagcaat
    14701 caagcaggta gcaaacatac gtgatcagct gattgaagct tacccagaaa aacaggaagt
    14761 atggacaaaa aatgcagcag cctataccga gaaacttcaa gcactccatc agctttatca
    14821 agaaaccttt aagcaagcaa aacaaagatc ttttgtcacg caacatgctg cattcaacta
    14881 tctagcgtta gaatatggat tgaatcaagt atcgattgct ggtctttctt ctagtgaaga
    14941 accgtctgcg gcgagaattg ctgaactgaa acactttgtt aaagaacatg gaatcaacta
    15001 tatttatttt gaagaaaacg ccaaagatag tattgccaga acgttagcaa acgaagcagg
    15061 tgtatcttta gaagtattga atcctttgga aggattgacg aatgaacaaa tagaaaatgg
    15121 agaaaactat ctttctatca tggaagcaaa cctcgaagcg ttgaaaaaaa cgacagagac
    15181 agaaaacccg ctagaagata ctttgacccc caaaaaagaa aagagcgtct acaacggtta
    15241 ttttgaagac gaggatgtac aagatcgctc tctttcagat tgggcaggaa cttggcaaac
    15301 agtagatacg tatgtagaag atgggacttt tgatcctgtt tttgaatata aagaaaaatt
    15361 gaatcaggat aagacagcac aagaatataa agaatattat acgaagggct atcaaacaga
    15421 tattgcttca atcaagatca gtgagaaaga gatggcattt acgtttaaga atggaacaac
    15481 gaaacgttca aattatcgtt atgtagggaa agaaatcttg acctacgagg caggaaaccg
    15541 tggcgtaagg tatctattcg aagcagaaga taaggaaagt ggcgctttta gatatattca
    15601 attcagtgat cacacgattg caccggctga ctccgaacat tttcatttat atgcaggaaa
    15661 tgaaagtcaa gaagtattgc tgaaagaaat ggagaattgg ccaacatttt atccagatac
    15721 aatggatgga cgtgaaattg cacaggaaat gcttttgcac tgataggcaa aaaagaaccg
    15781 aagggtttgg atcggctggt catttagtcg gtccaaacta ttcggttctt tttatgaaat
    15841 caatttcttt aatccacgga tagaggctgg gatggtctcg ccgtttgcca acgtgacttc
    15901 tctggttttt ttattaatcg accgcacatt ttgtgtattg ataacatagg atttatgaca
    15961 acggataaaa ttccgatgca ttttctcgat ttctttgatc ttctcataga attgtaattg
    16021 ggcatgagtc aaatggactt ccagtttatg tggcgctcct agcgaagtag aaaaatattg
    16081 gatgtctttg atcggtaaaa atttgatctc atcattaaac tctattttga agatatcttt
    16141 ttggatttgg gacatttgaa aatcttcgaa aattttgctc aggatatgct cgacattttc
    16201 ttttaaatca taaagatctt ctttgacgat ataatcagtc ggttcgatgt tgctttttaa
    16261 gattttcatc gacatttccg tatgggaagt cacatagatt atttttccta aaggatctaa
    16321 ttcacggatc aatttaccga tcgctacacc atccatttca ctgtcttcta gttcgatatc
    16381 taaaaagtaa ataccaaaag aagaagttct gatcttggct gcattgagaa gttcttccgg
    16441 atcagaggta gaaatatgga cataactgtc taagttttca atcatgattc tatttttgat
    16501 caccgttgat aaaacttcta attgttttgg atcgtcttca caaatataaa tgggaatcat
    16561 atcattactc ctttatttta tttgtatata aatcgtttga gaaaaacgct ggttttcaat
    16621 tgatgtttca aggaaaagat aaggattggt ctttgtcaat tcatccaaga taaacaagcc
    16681 aaggccttcg ttttttggat ttgtttttgt tgagaaccct ttttgtttca actggtttaa
    16741 cggtaatgta tttgttgttg tattgatcac acgaatcatc acggaatgat tcttcttgag
    16801 tatggtcaat tcgatttttt tcttctttgc agcactagct ccttcaatcg cattgtccaa
    16861 gataatacca agcatacgta caaggtttac cgtatgtttc gtatccagtt cgattggctc
    16921 aggaaaatga agctggacga tcaacccttt ttcctgtgcc atcatgagtt ttaatgacag
    16981 taaactacgg atctcaggaa ctttcatatt atccaacata cttagattgg ccggaaaaag
    17041 gttcatcatc tggcgtgtag gtaatatcgt ttgatcataa taagaccgta atccttctaa
    17101 gtcgccttct gaaatatagc tgtgaagaga aaaaagcaga ttttggtaat catgtttgaa
    17161 ttctctcaag tcttgatagt ttttttctag atctttgata taatcctgtt gcatcctgac
    17221 ttgttgctct aataactgat cagctaattt cttattagag attttccaat aataaaccaa
    17281 gatgatcagg ccaacacaca gatatagaat gaaaaaactc gtattcaaag ctaagacatc
    17341 aggtgtttca ccagaaaaac gggtataaaa aataatgata tagtatgtaa ataatatcaa
    17401 tgtcccgatc gtaccgatca tacggcggtc cacagtgtga aaccaagtct ctaacgattt
    17461 ttttaaacaa aaagctaata aagcagataa aaaagcggat aagacaatgt gaaaatactg
    17521 caatgaatct cctggttcaa taaccgaaga tttcaaaaca aaaaaatcgc cgatgcttgt
    17581 taagtgatct cctaaaagcg acgtcaataa cccaaaagga agcgcgtaaa ccaattgttg
    17641 acgcgaagtc gaaaagaaga aaaaagtaag catcagcatt cctatagcaa ttagagcagt
    17701 aaaaatccct aaaatcgaat agacccatcc aatcaaaata caagaaatca gaatgactcc
    17761 cgcaaacaga tatttgtatc ggatgtgatg gtcaatcaat aagatacaaa ttgtgtaaat
    17821 caaatattgc aacgctatgg accataaaaa cataaagtac agctcccatt gatttttacc
    17881 aaattatagc acaattggcg tattattttt ttaatttttc agggattttg aattcagaac
    17941 tcataccaaa gcagcagcca gatacaaaaa agtcagataa gttagttaat tgtttaatga
    18001 ttgttttttt catgaaagat tcctccaaaa ttcatcaagt agtttgtaat aggaagcaac
    18061 gtagctattt ctaaaacaat cccaagtagc aaataggtag aaaagtaaga agctgagaaa
    18121 aataacgtaa tgagagaaaa aattagaaac atgctgatcg ccttctttaa taatggggga
    18181 cgtttctcgg gttcaatggg attgattgct gtacctcttg atccatagcg aagcagtaac
    18241 aaaaagcagc tgattaacaa aaagaccatc attgggaagg agatagtcaa ttgcagatgt
    18301 ttcatcacca agggaacgcc ccataaataa agtagtgtcc acagcagaca aacgaattca
    18361 gagtcggaat gcaatccata agcatatctg cggatgcaga tataagaaag aaaggtgatt
    18421 cctgtttccg cccatgagcc tgtcaccaga gaaaagacta gaacgaccgc tagttttcca
    18481 agattattca ataaaacttc taagacaaat tttacttgga catacaccat atcttcttcc
    18541 gatttgtctc cgctgaataa ggcttctaat aatttgttca caactttatc tttcatctca
    18601 tacgtacctc caccacaaat tttatgctaa aaaaaataaa aaacgtcttt tgtttcataa
    18661 aaagtggttt tgacatcaaa accgtcatga tctcctaaaa aaatcttcgt tttccaagaa
    18721 ccttaccaaa aaaagtgaca gttttgatac gaaaagtact ttttatgaca agtttgtgct
    18781 ttttcgagtg atttatgtta aaaaattact gaccttataa aaggtgatgg agggattctt
    18841 atggaaaatg aacaattgtt tgaagtcggc gaaacatatg catttaaatc tgatttattt
    18901 gaatcaccaa taaaaggaaa aatagaaaaa atctatgaaa atagtgtgat gatacgtgtc
    18961 atgaaatgcg cagtagaaga caatgatacc gctcataatc tgcactggca gttagttgta
    19021 cgcaaatcaa gtacaataga agaataaaaa cagataaaat gttgagagca taaagaggtt
    19081 gtgagtctcc cgtttagctc tgagttacaa ggaataatgt taaaaaacag cttttcatgt
    19141 tttatgaata ttgccttgtg accgaggtgt tggcaggaga atactgttta tttgaaaaaa
    19201 gggctgcgac aagacttttg tcacagcctt tattttcatg aataggagtt acttttggct
    19261 acttttagag aagtagcttt taaggagcag ataaagtcaa ggcttttatt tctataaatg
    19321 aagtagtaaa atgaagaaca gattttatta caggaaggat gccgataatt gtgatcattg
    19381 ttgcaggaac gatcggtgca gggaaaagca cactaactga aatgcttgcc caagatttag
    19441 aaacaaaacc tttttatgag aacgtggaag ataatgaagt attgccgcta ttttattcta
    19501 atccagaaaa gtatactttt ttattacaga ttttcttttt gaacaaacgc tttttggcaa
    19561 tcaaagatgc tttcagccat gatgacaacg tactagaccg ctccatctac gaagatagta
    19621 tgctgtttca tttgaatgca gatttagggc gtgtttctga agtagaagta aagcagtatg
    19681 aaggtctttt agaaacgatg ctgaaggagt tagaagaaat ttcgccacaa aagaaaccag
    19741 atctactggt ttatattcgt gtatcctttg aaactatgtt agcgagaatc aaaaaaagag
    19801 gccgggaata tgaacagcta gaacaagatc ctgaactcta ttcctactat aaagaactca
    19861 atcgacgata cgaagagtgg tatgaacagt ttgatatatg tcccaaaata gtgatcgatg
    19921 gggacaaata tgatttcgta gccgatccgg catgtggaga acaaatcgta caagaaatca
    19981 agatgcgggc aaagaaaatg acagaagagg cagatgccca gtcgatccgc tacactacaa
    20041 ataacccgaa agcaaaggga atctttacaa ctaaataata taaaaactaa gcaaattgct
    20101 cactcgcaga tatttctctg tgagcagcat cttgcttagt ttttttgatt cattgagatc
    20161 aaatagtgaa ccgattcgta tgataaaatt gccataaatg aaatgtctga gtgagggcca
    20221 tgatcaaaaa taaaatggaa acgatcaaaa tcgaatgggc gccaaacaga tgatgacaga
    20281 aaacaaggac aatagctcct gcgataaagg caagaacgac acttagatag tggaaaaatc
    20341 gatcaaaatc tgctttttct ttagaaatac aataatcata taagttcgtt gctacccctt
    20401 ttaaatttcc agttgtaaat aaattagtgt aggcacgccc gttgatttta tcaaaagcta
    20461 cccactggat cgatgcagta aaagcaatca aaatcgttac taatgcggga tgctcatgga
    20521 cgggtgtcaa actaacaaag aaaaaaatca ctgcttcata atatagaaca aacaagcgcc
    20581 agaaatgttt ttcttttttt ctaaaataat caattagata ctttgttaga agaatcccta
    20641 agaaaaagaa aagggtagac aatacttttt taccaacact tagccattct ccgtcaaatg
    20701 cttggatgat cgatagaatg atattgccag tttgagcaga ggcaaaagca ccatattgga
    20761 tataagtata actgtccatg gctcctccga taaatgtcag caaaagtcct attgtacgcc
    20821 cctcgtgaaa ggaagtctgc atttttttca tcacctttta tgaatatttt tgtcttcctt
    20881 atcttagcat aaacgattga aaaaaaggaa aaattttcag aaaactaaaa tcatatcgct
    20941 tcccattttc atttttagaa aggtctgtta gtataaagaa aaaatagaca acgaaacttt
    21001 aaataaccaa cttgaaataa acaaattcaa agaagaaaga tgggaaggaa atcaatcagt
    21061 tgaatgaaaa agaaattctc cgattacaaa aagaattgaa acgctgggag aacaagtata
    21121 aaaagcttca acaagtcttt cggctacaag aagaaatcat tgctacctat gaagcggctt
    21181 atggcgaagc acccggactt attgaggaag aagtacaagt aaaagaaagt gaaggaaaca
    21241 gctctttctt taaaatgatg gagaaacgtt cctataatcg cttcaatcaa gaacaaaaag
    21301 cagctatcac atatgatatg aagaaacatc ttcgaatcat agcaggagct gggagcggca
    21361 aaacgcaaac aatctgtgca aaagctgttt atctgatgac gcaaaaacaa gtagacgaag
    21421 aacgcatact aatgatcact tttacaagga acgctgcaaa tgaactaaaa aaacgagtag
    21481 ataatttcag ccagagaaaa accgctgtcc atatcggaac attccatagt atctttttta
    21541 ggatatacaa tgaaatttgt cgaaaatttc ctgaagtagc aatgcaagga atacaaggag
    21601 acttttcaaa ggatactgca caaaaagtga atgctgtttt gcaacagctg atacgtaaat
    21661 ataatcttta tatatttgat caatatggag aaaaaacgat tgcttctcgg ttagactatt
    21721 ggcagaatat gaacctttca gtagaagaaa tggttcagtt agttaaagaa aaatatgatt
    21781 ccattgataa gaatgcacga cagccgatat cagaacgact gtatggattg ctcacggaac
    21841 tccaagaaca aaaaagaagc cagcaattgc tagagttcaa tgatgtactc caaaatctga
    21901 aaagcgcttt ggagaatgag gagatccagc attatatcgg ccaaaaatat gattatctat
    21961 tcattgatga atttcaagat actaatccac ttcaatggga aatcgtgaaa cggatgacaa
    22021 aggaaaacag gatcaagttg attgttgttg gagatgatga tcagagtatc tatggattca
    22081 gaggatcaga gccagcatac atcaagaact ttgaaaaaga atatcctacc aaaactcttt
    22141 tcttattaac taattatcgt tctcgggcag ctattgtcca aggagcaaat agattgatca
    22201 gctataataa aaatgatcgg ataccaaagg cgatgattcc agcacaaaaa gaagcaggtg
    22261 ttatggaagc ctatttgttt tctgatacta aagcagaaag tcagtggcta atcaaacaaa
    22321 ttcagacatt tattcaaaaa aatgggaaat ataaggaatc aatcatatta taccgatcag
    22381 cttcacaaac gcagcagctt gtccaatctc tgctgaaaac gaatattcct tttgtactgg
    22441 aagcagatag tccatatgaa ggtatctttg gtatcaagtc tttccaacat ttctatcaaa
    22501 aaattgttca ttggcaaaca gcactgaatc tgcaaaagaa aaatcaggcc taccagcaat
    22561 tgctccggca gctgatggca gactgctacc tgaaaaaaag tgaatgcgat caatactttt
    22621 ctcctaaata tcaaaatata gccgttgcag attatatttt gtcgataagc cccaatttaa
    22681 aatcgaaatc tgcagaaatc cgagagtttg aggaagcgtt gcgtaaaaca gaccagcatc
    22741 aagaaatcta ttcgcttgtt caaagctatc ttcatctgcc acgtatagct aaggaaatcg
    22801 accagagtga tcaagaatgg atacgagaag aagtaaagca gcatgctact ttcagaagac
    22861 tccaagcctt atcgcaagaa acccaagcga cagctaaaga attaaaaacc cgcttgattg
    22921 cttacagaca aggaaaactt gatgcactat gtatccagag cattcacaaa agtaaaggtc
    22981 ttagttaccg aaatgtcttt ttgattggtt gtaacgaagg aagtttgcct tataacggag
    23041 cgacagaaaa gaaagtaatc gactttaatg aaataaaagc agaaccagta acgacgatag
    23101 aagaagaacg aagactattt tatgttgcga tgactagagc aagaaatcgt ctgtatctat
    23161 gtgtacctca aatgaaaaat tcaagaaaat tgaaagtatc gagatttatc aaagaaaccg
    23221 ggagtcgtgt gaaaaaagga aagtgataga agagagggtg tgacagaagt ggtcagtttc
    23281 aagaaagaag aaggaatgta cgaaaattgc ttctcaaatt tttgtgaaat ttcagcttat
    23341 tttcgaagaa gctatttctg gaacacagtt tattcggaaa agggaggtgt gacaagaatt
    23401 ttgtcacacc tcccttattt attttgaaaa tgagaatact attatcaaaa tagagaatat
    23461 atagaaaaat tctcattatt caaacgtaaa taatcagtta ttttgatttt ttttatattt
    23521 tattagctaa taattggtat tttaaaagaa attactgtag aattggatta taattaaaaa
    23581 ggagtgagaa aatgataaaa gtatatactt cgcctagctg tacttcctgt agaaaagcaa
    23641 gagcatggtt gcaagcgaat caacttgaat ttgaagagaa gaatattttt gccgaaccgt
    23701 taacagaaag tgagatcaaa aagatcttgg cagcgactga aggaggagtt caagatatta
    23761 tttccactcg gtcgaaaatt tacgaaaagc tgggcataga ttttaacgaa ttaactttaa
    23821 agcaaatgat cgtcttattc aaagaatatc cttcattatt gagacgacct attttgattg
    23881 atgaaaaaag aatactaatc ggatttaatg aagatgagat ccggtcattt gtccctcgtg
    23941 aaattcgatg tgttgccaga aatctgatct atttacaaaa caataacatc ttaaattcat
    24001 agggagggag ccttcgtgga agtgaaagtc tatggatcag cgcactgtgt aacaagtctg
    24061 aaggcgaaac aatggttaga acaccatcaa ttgccttatc aatttgttga cttagaagaa
    24121 cgcgatttaa gtacagaaga agcagaagaa ttatgcagtt ttgaagaagt gcaagcagaa
    24181 cagctatttg cgacttggtc tgaggctttt cacaacattg cgattgacct ttcctgtgta
    24241 ggaaaaaaac aactgatttt tttatgcaca caacatacca atctcctcag acgtcctttg
    24301 attattatcg atgaagttct atttattgga tacaatgagc agttgatgga acagcttatc
    24361 ttaaataaat agactttaac tgttttaatc aagtcactga gcatttcata cagttgtaac
    24421 agtcgaacac ttagcatcaa gcgtgttatg tgttcttttt ttgactttat ttttctacta
    24481 tagagacatg ctcaatttat gtggtcaaaa ttcaaatcta ggtggggata tagagttaaa
    24541 aatatattga catgtgtaaa tttacatgat atattcattt ctgttgtttt aagtagcaaa
    24601 gcaataaaat agtattttaa aaaacatata aaatagttgt tgacatgtta gaaatgacat
    24661 gataagataa ctgagttgtt aaaaaagaac cacttgtgaa gcttgattct atcgaaaaaa
    24721 acttcaaaaa agttcttgac aaataacaaa tgataagtta tgataaatga gttgctgtaa
    24781 gatttcgaaa aacgaaatca aaaaaacttt taaaaaagag ttgacaatta cttgtctctc
    24841 tgatatgata taaaagttgc tacggcagcc aaaaacgaat cggggaacac tcctgatgaa
    24901 gtagaccttt gaaaactgaa caaagtaaga caaaccaaat gtgtagggcg tcttgattca
    24961 attcaagaca acaaaca
//
LOCUS       DAZKKZ010000044        24475 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.045, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000044 DAZKKZ010000000
VERSION     DAZKKZ010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 24475)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24475)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24475
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.045"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..1359
                     /locus_tag="ACG8LA_001878"
     CDS             <1..1359
                     /locus_tag="ACG8LA_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HFQ0204174.1"
                     /translation="LFSDEEISVSVPEAAATIIPVKGHQRVVGTKADKIKHLPITEKE
                     HLLPLEEQFCEHCGSQMKDIGRTKVREEIRFHQAMLDCLTHYQHTYCCKSCEKEGLSS
                     FKKAIVPKPLISNSLGSNSLVAETIRMKFGQKVPAYRQENYWKQTHGLDISRDNITNW
                     HIKAVQNALDPLGERLRVYLNQEEILHGDETSYRVIESAKTDTYYWQFCTGKDSQHPI
                     VYYHHDESRAGDVPKTFLKEFTGYLHCDGYSGYNAVESVRLVYCFAHVRRKFFEAIPK
                     GKKNTDIPAAQAVKQLDKWFVLEKKWKDFSPEKRLSCRQQELRPLFIAFYEWMATIDP
                     VAKSKLDAAVQYACKLRSGFEPIFEDGRLELTNNRAERNIKELVIGRKNWLHSTSLEG
                     ARTSGIILSVYKTAELNGLNPVKYLEFLFDKIPNLPVLSAETLDQLLPWNKDVQQHFS
                     RN"
     gene            complement(1432..4005)
                     /locus_tag="ACG8LA_001879"
     CDS             complement(1432..4005)
                     /locus_tag="ACG8LA_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ig-like domain-containing protein"
                     /protein_id="HFQ0204175.1"
                     /translation="MNQYVKKLIASILFVFPLLMVTSVFADVEKTSESTQSENQSFDK
                     TTFSEESITSETTESQSEAPTSNTRQEENKTSETSEVAEQTSDSSEEVQVRVVSADGY
                     SEAATTEELTQLLADESVAKIRLTQPLTLDRELEIKRDIVIDFGGLAHNFGTHHIYIN
                     ETPQSIEFQNFKGTAAHPGGLIPNIDGNAIIIAYMSDFWGNRYHFTGEIKFTGTLDLY
                     DGSKLGLIYAPRATVTLDGVSGVLDVQPVKEGMNAAPGKAYFCRSYQLNVINGSQLYG
                     PYLGKFYGFLDSGDETGSGKTAPGLHILSGSKVSLDYDRADGVSDEGEAVDTLPGNVT
                     FKVSGSGSEFSVNTKINITNDNNRGIIQMRGSGSRVAVSNDGKITINTATTGGFRLQG
                     DSSQIHVSSGGQISVKMAGDGDQPGNNGMRFVGKGLSLIVEGAGSVIDIDKQSGRSSA
                     VRFENGTQKLTVTNGGSLKVRNAGDGKSYVNRLNQGNQAIQFYDASGFLESPGSADFT
                     VTGEKSNIDIRADSGATVDTTGDIDLNFMAGEKTYLVMVGKTGEDKTGIISGDVLNVD
                     LESPTYFDFQNKRIGSETNGIGGWVFQGNGDSSLKIAHSEIALWRKAGVTFDNFEKDP
                     DYFSDMTDLSINGTDLGNFVSSPSAGLTNEFAQTGAGMKNYNRISANNQLPMIESLRV
                     PTNADKKIYGHVVVPEGVEAKPRDAWTGEVEVTLRITYADTTKSPVEITALTQGQTDE
                     NEGTGYNPWGEGEQGGLFEVQVPNEERLTTGDQVQIVAAKKVRGGQEVTELDSAKTTV
                     DVIPPEPAKLSTTLINAASRSITGTGEAGALVSLKKNQAVLSETTIDDTGKFVLSIPE
                     K"
     gene            complement(4227..5111)
                     /locus_tag="ACG8LA_001880"
     CDS             complement(4227..5111)
                     /locus_tag="ACG8LA_001880"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HFQ0204176.1"
                     /translation="MKKVLLVVNPSSGGEQAKEFEQLAIAKLESVFDEVVVLHTKKAG
                     DAKNFTREAATEGYHSVFVMGGDGTVNEGISGIAEQEHRPNFGFFPLGTVNDLARALG
                     IPLEPEEAINHFSIESVKPLDIGKINDDYFMNVVAIGSIPEAINDVDAEKKTKFGKLA
                     YFMSGIKQLASTQSYSFHVEVDGKKEEIESSILLIGLTNSVGGFETLLPNAKVDDGKL
                     HLVYLKDSSLIDTLKTLPDLLKGVDESTKNLAYLTCEQLVVSLADEEELTTNVDGDEG
                     DKLPVTIKVLPSHLQVYC"
     gene            complement(5206..5643)
                     /locus_tag="ACG8LA_001881"
     CDS             complement(5206..5643)
                     /locus_tag="ACG8LA_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204177.1"
                     /translation="MEWFCKFLLFLEVIHVYGFVFLTNKKAGSTMDHLYIKYIHQFSV
                     LVLGTLIIAGIVAFIIQGRDILTVHQEFFSYAFGIPLIAIRSDNKKWKKRYYILLLFL
                     CFYLPPKIFTLLGIQCLSFSFISYIIVLIFLSFIVWVFYLVKK"
     gene            complement(5860..6771)
                     /locus_tag="ACG8LA_001882"
     CDS             complement(5860..6771)
                     /locus_tag="ACG8LA_001882"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFQ0204178.1"
                     /translation="MKKRFLALAIVLGTGLLSGCTNAGEKTAVSYKGGTISEQEVMDS
                     LKKMQGADSAVQQLIVYQVFEDKYGDDVSTKEIDSQYDQTKKQLGDSFDSQLKSAGYT
                     EQTFKDSIKQSLAFQEGLKKHIKLTDEDLKTAWESFHPEVEAQIIQVASEDDAKDVKK
                     AADKGDDFSKLAKDKSTDTTTKEDGGKVKFDSTTTTVPAEVKEAAFKLKDGQVSDVIT
                     STNASTYTTEYYVVKMVKNQNKGNDMDKYKKELKEIATDTKLSDSTFQNKVIGEVLKD
                     ANVKIKDKDFENVLSTFTSDSSTASSK"
     gene            complement(7148..7786)
                     /locus_tag="ACG8LA_001883"
     CDS             complement(7148..7786)
                     /locus_tag="ACG8LA_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0204179.1"
                     /translation="MEPLIVIKGAKKIIRNKTILHLDRFTADAGDFVTVVGESGAGKS
                     TLLNILGLNDQFSSGQFYLFNQETKHLTGREKRLIKRNALSFLFQDFGLIEYETIDFN
                     LDIGLKFSNLNVSDKRTAKYEALKKVNINKKLSTPIYTLSGGEKQRIACARVLLKNSK
                     IILADEPTGSLDKRNKEQVVEILSQQASQGTLVIVVTHDPYLTKIGNKKIML"
     gene            complement(7790..9772)
                     /locus_tag="ACG8LA_001884"
                     /pseudo
     CDS             complement(7790..9772)
                     /locus_tag="ACG8LA_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370994.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
     gene            9952..10617
                     /locus_tag="ACG8LA_001885"
     CDS             9952..10617
                     /locus_tag="ACG8LA_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0204180.1"
                     /translation="MNIGEKIRTYRRNCKLTQKELGEKIGVSDKTISSWENSRTMPDL
                     EMLSLLHQTLGLPIDFPSIESATESIEPTLPDEPLVIKKSYSSKQPFSLKKTLSFFLL
                     VFCLVYLFLINYQYKNETVDRFNPFLKPQIGYTTLPVGYVENSIEHWVCNDIFVHGTW
                     LSFHAGEVEKGKNHAVIKHKGKHVMNVRLLTWEAIPSDYQEILIQDYDDALKRSPQEP
                     DRH"
     gene            complement(11014..13047)
                     /gene="brxL"
                     /locus_tag="ACG8LA_001886"
     CDS             complement(11014..13047)
                     /gene="brxL"
                     /locus_tag="ACG8LA_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005575 - cellular_component [Evidence
                     IEA];
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="protease Lon-related BREX system protein BrxL"
                     /protein_id="HFQ0204181.1"
                     /translation="MEQQEILKLSEFFPGKIVRKDLTKKIKEGANVPVYVLEYLLGMY
                     ASSLDETLVEKGVENVKNILARNYVRPDEAEKVKAKIRELGGYTVIDKVTVHLNEKKD
                     CYEAEFSNLGLKNVQISEEYPKKFDRLLGGGIWCIVSMEYWYDENDRWNSPFIAKKVD
                     PIQMPGLDIEAYKMARKEFTTNEWIDLLLRSIGMEPTQFNKRVKWLHLARLIPLIENN
                     FNLCELGPRGTGKSHVYKEISPNSILVSGGQTTVANLFYNMASRTMGLVGMWDCVAFD
                     EVAGIKFKDNDGVQIMKDYMASGSFARGKEEKNASASMAFVGNINQSVDVILKTSNLF
                     EPFPEVMGTDSAFLDRMHCYLPGWEIPKYRPDFFTNDYGFITDYFSEVMRELRKVSFG
                     DSFDKYFKLGSQLNQRDTIAVRRIVSGMMKLLYPDGRFEKSDVEEILRFALEMRRRVK
                     EQLKKIGGMEFYDVNFSYIDLEEEREEYVSVPEQGGGTLIPEGLGKPGHLYTVSYGKT
                     GQLGTYKLETQMTSGNGKFERTGINSDAGAREAMDSAYRYLRANYGSVSQSISLTTKD
                     FVVHVQDMNGIGMTKTLSLSTIIALCSVSLNKPVLPSLVILGDITIGGSMIKVDNLAN
                     CLQVAKDAGAKKVLVPMISAADIGTVPPELMGTFNLIFYQTPEDAVFKALGVE"
     gene            complement(13165..15687)
                     /gene="pglZ"
                     /locus_tag="ACG8LA_001887"
     CDS             complement(13165..15687)
                     /gene="pglZ"
                     /locus_tag="ACG8LA_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BREX-1 system phosphatase PglZ type A"
                     /protein_id="HFQ0204182.1"
                     /translation="MTDINTQQIEEKLNQRFPNYGCRKIIFWFDSNQDFLEEIDSLVI
                     QNAKIYRLEKDAQFKTKRLLEYEDPETNYLIYAPFPRWDDKDEDNHLLSVLNYSEEFS
                     ADRLAIIMNELAIPLRFHQTVKQYRNFFNAKDRMRSFGEFSTHMTINKSETIELMIMA
                     VLLKSKSIRLNDLLRVVLKSFTESRENPLRELDKYQLTAKFWEFIQMKFGFTDSQPTL
                     EKLTMCLYLNYFYYQIDQEMPKKFKGFEILHLKANIITFMDQFMNDTRYMESFEQLSK
                     KVYQAIDGDGLLDSIEIDDLIEADVFSEIHAKILMFYAERLKASDTTTKIAGQTIFDS
                     LKQREKMHFASDYIYEYQLLKHAYYLVDKNRLCLPMNMDNLLTQYEKEMYWVDTHYRK
                     FIWNSDHIEEKQKYGQLYRLVEANYSKFLDQSGQIWNQTFEFKNRPSIRKFYNQAVMK
                     RSVKTVVIISDAFRYELGMNLERKLVREKKYSTNMASFLSVLPSVTEFGKAALLPNNQ
                     LTYNEGTEVLIDGKKTNGLSNRNAILQQRDANAVALNYDDVVKMNKAEVREVFNGKSV
                     IYIYHDQVDRTGDHSNENRVFEACDLAISEISRLINRLHNDGSIYRFIVTADHGFIYK
                     RSHVEEVDKIENPSRNEKDRVERRFILSEEEYEIIGTKNYSLGDSLGNDDTRNICVPI
                     TSSIFKKAGGGQSYVHGGSSIQEMLVPVLEITVAKGSNAKEPVAIELMTSNRRITGLS
                     TTLEFYQKNAISDVYDPASFWLYFEDEYGERISNEEIYVADSKTEDANQRFTKFVFEF
                     VNRRYTVEDTYYLVIKNQKNDLTERIKFIIDNPFAESFDFDI"
     gene            complement(15803..19435)
                     /gene="pglX"
                     /locus_tag="ACG8LA_001888"
     CDS             complement(15803..19435)
                     /gene="pglX"
                     /locus_tag="ACG8LA_001888"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008170 - N-methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BREX-1 system adenine-specific
                     DNA-methyltransferase PglX"
                     /protein_id="HFQ0204183.1"
                     /translation="MDKKAIKNFAVNARRKLIDEVMTKAKRLGIDESKIEDVKKIDSN
                     LQEIEKSGIRIQGKEIAQRNKLIAELKQRASVTSYSEAFQELIEEVAYTWFNRLIAIR
                     FMEVNDYLPDTYRVLSSEISGKIEPDIITDIYDADIFEELSSNEQQQVRTWKTDNSAE
                     AMDKLYQLIFIKICNQLNDYLPELFEEVEDYTELLFTASYIKKDGVIADLLSIPEDDF
                     YVQAGGQVEIIGWLYQYYNSEPHNQVVNIYKGIVKKQDIPAATQLFTTDWVVRYMVDN
                     SLGKYWLDHYPNSELRNKLKYLIPDKYAFEQATSVSNLKPEELKIIDNAMGSGHILVY
                     AFDVLMEIYLTLGYSERDAARAIVEYNLYGLEIDKRAYQLSYFAIMMKGRQYDRLFLK
                     KSLSPNLREFIDSPKVTDEYQERISELNNDKYSERWNEYKELIFDQFENGKELGSIIK
                     LVDKNNQAITKEYLGKVREYISKFNEFTNMDILYGMKEIQEKYLHILDVAEMLVDKYV
                     AVVTNPPYLNKMDKKLKKYVNDNYSDVKKDLFSVFIKLNSQMLIDNGYASFMTPFVWM
                     FISSYEKLRSFLINERNISSLIQMEYSAFEEATVPICTFTIKNSNEQDGSYIKLSDFK
                     GGMEVQKIKTLEAIHQHGECDYFYSTNQDNFKKIPGMPIAYWASDNVITDFAQGKLTN
                     DVADAKQGLATGNNNKFLRYWFEVEFNKIKFDAKTLEDAKKSRKKWFPTTKGGRFRKW
                     YGNNEYVVNWENDGDEIKNYVNENGKLKSRPQNLNYYFKKGITWSTLSSGQVSFRLQN
                     QAIFETKGSVLFSKDITDFEEIFGYVNSKLVNHFLTFISPTLDYHEGPMGKLPFLKVT
                     SERKLKKIREKVDENIDIARKDYNALETSYEFRRNILLSYMFKKDLSEAFNCLSRQLV
                     NQFNTLKSNEEELNDIFINHYSLEKELTKEVQDEYISARLPDKAREIKDFISYSIGCI
                     FGRYSLDEDGLIFAGGEWDPSRYQKFKPDTDNVLLITDDEYFKDSQIDIVNRFIDFVE
                     ITFGKETLEENLQFIADTLGGKGTSREIIRRYFVQDFYKDHLKTYSNRPIYWQLDSGK
                     QNGFKALMYLHRYTPDQLGKVRTEYLHELQKAYDNRIELRQQQISTSDNPKERNAMTK
                     EIVKIQKQLKEVREYDEKLGHLALKRIELDLDDGVIVNYDKLQRDPKTGEKFQIFAKG
                     VKEPKK"
     gene            complement(19499..23170)
                     /gene="brxC"
                     /locus_tag="ACG8LA_001889"
     CDS             complement(19499..23170)
                     /gene="brxC"
                     /locus_tag="ACG8LA_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BREX system P-loop protein BrxC"
                     /protein_id="HFQ0204184.1"
                     /translation="MLIKDIFAKPIDRNIQGVIKVGQAKDENVQQELEEYVVTKELQK
                     HFKTIFDAYQRSINTPTDKMGVWIQGFFGSGKSHFLKIISYLLANREINDKKAIDYFK
                     EDGKIKDPLTLATMERCSQINTDVILFNIDSKSDAGGKKDKNGIVNVFLKVFNEMQGL
                     STIPHLADFERRLIKEEKFDAFKAAFEEINGAKWQEERHEFDWIQDDIKEAALKIDFM
                     SEAAIDNFLEKASGNYLISIDDFANLVKSYLDSKEADHHIAFLVDEVGQYIGGNRELT
                     LQLQTVVEDLGRICEGKAWVLVTSQEAIDHVTNFDNNSDNDFSKIKDRFATTVSLSSA
                     NADEVIKERILKKKEFANDSLALQFETVQTELKNKLLFVDSPELKLFQDAENYAEVYP
                     FIPYQFNLLGQILTEIRNHSYQGSNLSSGERSLLAMFKEAAERNKENDTTSLVSLDQF
                     YYSLERWIDTAISRVITQATNNSHIQRPTDIDNFNVNVLRILFMIKYVDQAIKPNVEN
                     ITSLMIRNINEDRLETKKRVEEALDLLIKENFVRKNLDSYIFQTDEEQEITREIKNQN
                     ITDSDLIVELSKRIFDGVLDRNSFAYEKLGMSGGNKFKNRYTFTYAQVLDQRPYKQAG
                     NAEMTVNFISPYSDLAGQEAELALKSSRNLLFVELPSDKEFKDDIAMYARMNLYLTTT
                     YSSVVKNFDAIRSEKSGELQELSASINDQLNELLKSAKFFYNGAEIQLTGSDFKAKFQ
                     SALQKMAEEVYHKLNQIDAPKEKEDILYLVKESKNEIIEDPSNEQAVQEIFNFINDQK
                     RNHLTITMKTIRDRFETKQPYGFTELDVEWCIAKLFMSGKIDLLYNNVQISRMDDPNS
                     IVMIIQKRRESEKIKIEPSAVISPKAKKLVDEIGRELFQSRNIVDENNNEHTMENFKK
                     YLKGQLDNLRSYFDLQNTYTYPSAYEYEQIKKYLEVIVQTSDVEDFFYTIKKYRDELF
                     DWAETYDKIKNFHKQNSTQKKIWENAQDKIRLIEKSRRQTSSQEIDQLIHEMKTILKK
                     ADPYSDMMKLNELIQEFIEQYNQLLELESQEILNKLTEEKQATFKLLEGKDFKDQFVP
                     IVDQEFQELKAKIEQANTIDDLVFLSLNVAEQYLIFNQRFDNEENRRRQEEQARKQIE
                     AANLIRETEKDEIDSAAKAEEIAIVKPTIQQKTVPMRTLNVHVKTIKSAADIDELTAE
                     INQKLKEQLQENTEITIQF"
     gene            complement(23195..23770)
                     /locus_tag="ACG8LA_001890"
     CDS             complement(23195..23770)
                     /locus_tag="ACG8LA_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1788 domain-containing protein"
                     /protein_id="HFQ0204185.1"
                     /translation="MSLSIQEHLEKLNEVIQKEDFLLNRGLGNEVGYYIFDYDPKDEL
                     IVRDYINDISGTSVGDNYEVKVYNLYVIMLEYLEKRGFTEKAIKMEERRGLQKLVESI
                     GRLLKMDLPEEENVFFEYVDAHTPEKSVVFLTGIGELYPLIRAHSILNKMHQVFDRVP
                     VVMMYPGEYDELSLTILNTNKDDNYYRAFRI"
     gene            complement(23770..24369)
                     /locus_tag="ACG8LA_001891"
     CDS             complement(23770..24369)
                     /locus_tag="ACG8LA_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1819 family protein"
                     /protein_id="HFQ0204186.1"
                     /translation="MNKKYSAGLVSKRFWFSEFKLYIQLRLEGYTDIEIKEKNEHENI
                     FFAVSSNRQKEIYQNVKRRVSQLDEAGLQLFNQLNIDNQKLVNLISILMIDDLFNEFM
                     TEVYAENLRKGNLQLTPVDYRSFFTEKRRSSEDISKWKDYTIKRLIAAYQTNLIETGL
                     VRGEKEYGRMTPILLDKRLIQWLVDKNRKDIVLALGGIL"
BASE COUNT         7463 a         4793 c         3651 g         8568 t
ORIGIN      
        1 ctttttagtg atgaagaaat ttctgtaagt gttccagaag cagctgccac cattattcca
       61 gtaaaaggac atcaacgagt tgtaggaacg aaagcagaca aaatcaaaca cttacctata
      121 acagagaaag aacatctcct tcctttggaa gaacaatttt gtgaacattg cggttcacag
      181 atgaaagata tcggacggac aaaagtacga gaagaaattc gtttccatca ggctatgttg
      241 gattgtctca cccattatca acatacctat tgttgtaaaa gctgcgaaaa agaaggactt
      301 tcttctttta aaaaagcgat cgttcctaaa cctttgattt ctaatagctt aggttccaat
      361 agtttagtgg cggaaacgat ccggatgaaa tttggtcaga aagttcctgc ctatcggcaa
      421 gagaactatt ggaaacaaac acatgggttg gatatttcga gagataatat caccaattgg
      481 catattaaag cagtgcaaaa cgcgttagac cctttaggag aacgattaag agtctatctt
      541 aatcaagaag agattctaca cggggatgaa acaagttatc gtgtgattga aagtgccaaa
      601 acagatacct attactggca gttttgtaca ggaaaagaca gtcagcatcc catcgtttat
      661 tatcaccacg acgaaagtcg tgctggagat gttccgaaaa cttttctcaa ggagtttaca
      721 gggtatttac actgtgacgg ctatagcggg tataatgccg tggaaagtgt acgacttgtc
      781 tattgtttcg cgcatgttcg gcggaaattt ttcgaagcaa ttccaaaagg aaagaaaaac
      841 acggatattc ccgcagctca agcagtcaaa caattggata aatggtttgt cctagaaaag
      901 aaatggaaag acttttctcc tgagaagcga ttaagctgtc ggcaacaaga actgcgtcca
      961 ttatttattg ctttttatga gtggatggca acgatagatc ctgttgcaaa atccaagttg
     1021 gatgcagccg ttcaatatgc gtgtaaacta cgaagtggtt ttgaacctat ttttgaagat
     1081 ggtcgtttag aactcacaaa taatcgtgcg gagcgaaata tcaaagagct ggtgatagga
     1141 cggaaaaatt ggttgcattc cacaagtctt gaaggagcac gaacttcagg aatcattctg
     1201 agtgtatata aaacagcaga acttaacgga ttgaatcctg taaagtatct agagtttcta
     1261 tttgataaga taccaaatct tcccgtactt tcagcagaaa ctttagatca actgttgcct
     1321 tggaacaagg atgtacaaca acatttttct cgtaactaaa aacgccaaac attcccgatt
     1381 ctattctata ggtcgggtta tttgacgtac aggtactgtt ctatggggcg cttacttttc
     1441 tgggatagaa agaacaaatt tacctgtatc atcaatagtt gtttcggaca aaacagcttg
     1501 attttttttc aatgaaacca aagctcctgc ttcgcctgta cctgtgattg agcgagaagc
     1561 tgcattgatc aatgtggtac ttaatttagc aggctcagga ggaatcacat cgactgtcgt
     1621 tttggcagag tccagttctg tcacttcttg gccgcctctt acttttttag cagcaactat
     1681 ttgcacttga tcccccgttg ttagtctttc ttcgttgggt acttgaacct caaacaaacc
     1741 gccttgttcg ccttctcccc acggattata tcctgtccct tcattttcat ctgtttgtcc
     1801 ttgtgtgaga gcagtaattt ctacaggtga tttcgtcgta tctgcataag taatacgtaa
     1861 agtcacttct acttcgcctg tccaagcatc tcttggcttt gcctcgacac cttcgggaac
     1921 aacgacatgc ccatagattt ttttatctgc attcgttggt actcttaagg attcaatcat
     1981 cggaagctgg ttattggcac tgattcgatt ataatttttc attccggcac ctgtctgagc
     2041 aaattcattt gttaaacctg cactagggct tgatacaaaa ttacctaagt cggttccatt
     2101 gatcgataag tctgtcatat cagaaaaata atccggatct ttttcaaagt tatcgaacgt
     2161 tactcctgcc tttcgccata aagcaatttc tgaatgagcg atcttcaaag aagaatcgcc
     2221 atttccttga aatacccagc cacctatgcc attagtctcg cttccgatcc gtttgttttg
     2281 gaaatcgaaa taggtaggag attctaagtc tacattcaac acatccccac tgatgatgcc
     2341 agtcttatct tccccagttt tcccgaccat gactaaataa gttttttcgc cagccataaa
     2401 gttcaaatca atatctccag ttgtatctac ggtagctccg gaatctgcgc gtatatcgat
     2461 atttgatttt tctccagtaa ccgtaaaatc agctgaccct ggactttcta gaaaaccaga
     2521 agcgtcataa aattggatcg cttggtttcc ttgattgagt ctgttcacat aagatttgcc
     2581 atcccctgca tttcttacct tcaatgagcc tccattagtt actgttagtt tttgcgtacc
     2641 gttctcaaaa cgaactgcgc tagaacgacc actttgctta tcaatatcga tgactgatcc
     2701 ggctccttct acgatcaaag aaagtccttt ccctacaaaa cgcatcccat tgtttccagg
     2761 ttggtcgcca tctccagcca ttttgaccga gatttgtcca ccacttgata catggatttg
     2821 actagaatct ccttgcaggc gaaatccgcc agtagtcgct gtattgattg tgattttccc
     2881 atcattcgac acagcgactc ttgatcctga gcctctcatt tggataattc cgcgattgtt
     2941 gtcgttggta atattgatct ttgtatttac cgaaaattca cttcctgagc cactgacttt
     3001 aaatgtgaca ttcccgggta gcgtatcgac agcctctcct tcatcgctga cgccatctgc
     3061 ccgatcatag tcaagagaga cctttgaacc actcaagata tggagtcctg gtgctgtttt
     3121 tccactgccc gtctcatcac ctgaatctag aaaaccatag aattttccta gatatggtcc
     3181 ataaagctga ctaccattga ttacatttag ctgatagctt ctacaaaaat aagctttacc
     3241 cggagcggca ttcatccctt ctttcactgg ttggacatcc aatacaccgg aaacaccatc
     3301 taatgtgaca gttgcacgag gggcgtaaat caggcctaat ttagaaccat catataagtc
     3361 aagtgtcccg gtaaatttta tttctcccgt aaaatgatat ctgtttcccc aaaaatcgga
     3421 catataagca atgataatgg catttccatc gatatttggt atcaacccac ctggatgagc
     3481 tgccgttcct ttaaaattct gaaactcgat cgactgaggt gtctcattga tatagatgtg
     3541 atgtgtgccg aaattatgag caagtccgcc aaaatcgata acgatatctc gcttgatctc
     3601 caattccctg tctaaagtca aaggctgagt taaacgaatc ttagctactg attcgtctgc
     3661 gagaagctgc gtcagttctt ctgttgtggc agcttcgctg tacccatccg ctgaaacaac
     3721 tctaacctgt acctcttcac tgctatcaga cgtttgttca gctacttctg aggtctcact
     3781 tgtcttattt tcttcttgcc ttgtattaga agtaggcgcc tcactttggg attctgtagt
     3841 ttcagaagta attgattctt ctgaaaaagt agtcttgtca aaactttgat tctctgattg
     3901 cgttgattcg cttgttttct ctacatcggc aaaaacggat gtcaccatca agagagggaa
     3961 gacaaacaaa atcgacgcaa tcagcttttt tacatattga ttcattctcc accatcctct
     4021 ctgacgtttt gacaatttta ttttaacgtt ttaatttatt tgtaattgta ctttcatatt
     4081 taaaatatgt atttttatgg caaatttttc tgttaggtga aaatttcttt tttgtacaaa
     4141 aaaaggctgt gacaaaagtc ttgtcacagt cccttattcc gaacaaccga tgtcctcctg
     4201 acaactcttc ggtcacaacc tccattttaa caataaacct gtaaatgtga gggtaacact
     4261 ttgattgtca caggtaattt atccccttca tctccatcaa cattcgtcgt caattcttcc
     4321 tcatcagcta atgacacaac taattgctca caagtaagat aggctagatt tttcgtagat
     4381 tcatctactc cttttaatag gtctggcaat gttttaagcg tatcgatcaa agaagaatct
     4441 tttaaataaa ccaaatggag cttaccatca tccacttttg catttggaag taatgtttca
     4501 aaaccgccta ctgagttagt tagtcctatc agcaagatac tgctctcaat ttcttccttc
     4561 tttccatcaa cttctacgtg aaacgagtag gattgtgtgg aagctaactg tttgattcct
     4621 gacatgaaat aagctagttt tccaaatttc gtcttcttct ccgcatctac atcattgatt
     4681 gcttcaggga tagagccaat tgcgacgaca ttcataaaat agtcgtcatt tatttttcca
     4741 atatccaatg gcttgactga ttcaatcgaa aaatgattga tcgcttcctc aggttctagc
     4801 ggtatcccta atgctcgagc caagtcattc accgtaccca atgggaaaaa tccgaaattt
     4861 ggccgatgtt cttgttcagc gattccactg attccttcgt tgactgttcc atctccgccc
     4921 atgacaaaca cactatgata cccttccgta gccgcttcgc gagtaaagtt ttttgcatcc
     4981 cctgcttttt ttgtatgcaa gacgaccact tcatcaaaca ccgattccaa ttttgctatc
     5041 gctaattgct caaattcctt tgcttgttca ccgcctgaac tggggtttac cactaataaa
     5101 acttttttca tcactttctt tcccttctga ttgatttctt taatataacg atagcataaa
     5161 gaaaaaaatt aggctgtgat gaagtactgt tcatgaaaca ttcatttatt ttttgacaag
     5221 ataaaatacc catactatga aactgaggaa aattaaaaca atgatatagg aaataaaaga
     5281 aaatgatagg cattgtatac ctaataaagt aaaaatctta ggtggcagat aaaaacacaa
     5341 aaatagcaag agaatgtaat agcgtttctt ccactttttg ttatcagacc ttatagcgat
     5401 cagaggaata ccaaatgcat aactgaaaaa ctcttgatgt actgttaata tgtcacgacc
     5461 ttgaataata aatgcaacaa tccccgctat aattagtgtg cctaatacca aaacggaaaa
     5521 ttgatgaata tattttatat acaaatgatc cattgtactt cctgcctttt tatttgtgag
     5581 aaaaacaaat ccgtatacgt gaataacttc tagaaataaa agaaatttgc aaaaccactc
     5641 catttatcta cttctacgtg cattttttaa tatcgttttc tttatttaag attatacaga
     5701 aaaatatcta gggtggctgg attctaagta aaaaaaattt ttaaaataaa aagaactaaa
     5761 tcaagtaata attaaactac tgttgattta gttctaataa aaagatttag atgaacagtt
     5821 ttattgattt aaatagttca tattttttat ttataccgct tatttactac ttgctgtact
     5881 agaatctgaa gtgaatgtac tcaaaacatt ttcaaagtct ttgtctttga tttttacatt
     5941 agcgtctttc aatacttcgc caattacttt attctggaag gtactgtcac ttaattttgt
     6001 gtctgttgca atttctttca attctttttt gtatttatcc atgtcgttgc ctttgttttg
     6061 gtttttcacc attttaacca cataatattc cgtagtataa gttgaagcat tggtagaagt
     6121 gatcacatca gaaacttgac catctttcaa cttaaaggct gcttctttga cttctgccgg
     6181 aaccgttgta gtagtggaat caaatttcac ttttccgcca tcttcttttg tcgtagtatc
     6241 agttgacttg tctttggcta atttagagaa atcgtctccc ttatcagcag ctttcttcac
     6301 atcttttgca tcatcttcac ttgctacttg gataatttga gcttccactt ctggatggaa
     6361 agattcccaa gccgttttta aatcttcatc ggtcaatttg atatgtttct ttagaccttc
     6421 ttgaaaggct agactttgtt tgatactgtc tttgaatgtt tgttctgtgt aacctgcaga
     6481 tttcaattgt gaatcaaatg aatcacccaa ttgtttcttt gtttgatcat attgggaatc
     6541 gatttctttg gttgatacgt catctccata tttatcttca aatacttgat aaacgatcaa
     6601 ctgttgcaca gcggaatctg ctccttgcat ttttttcaag ctatccatta cttcttgttc
     6661 gctgattgta ccgcctttat aactaacggc tgttttttca ccggcattcg tacagcctga
     6721 caataagcca gtgcctagta cgatggcaag tgctaaaaat ctttttttca tttatcaatt
     6781 ctcctacttt tcgttttttg cgaattgcta aaaacaaagg tgttcaagat gaaaatcatc
     6841 aagaacacct ttactaatct gctcgatacg tcctgaatag atataaggct acacaatcca
     6901 gaaagttcgc tcagcagaat aaatgtcaag tagcacatca caccttaata tactacttct
     6961 tttgttaccg tttttcaagt ctatcttgcg ttccgtattt aacgtaacta attcttagaa
     7021 caaatgttat cgattttgtt tttcttcttc cgctgttggg atattcaaat cagacacttt
     7081 tatgttcgat tttccagaca tttttttgtt gtttttatta gaaaaagttt gttttttcat
     7141 ttgttttcta aagcatgatc ttcttgtttc ctattttggt cagatatgga tcatgcgtga
     7201 ccacgataac taacgtacct tgggaagcct gttgcgataa gatttcaacg acttgctcct
     7261 tatttcgttt atctaatgat ccagttggtt catcggctaa aatgattttg ctattcttca
     7321 ataagactct cgcacaggcg attctttgct tctcaccacc agataatgtg tagataggcg
     7381 tacttagctt cttgtttata tttacttttt tcaatgcctc atactttgct gttcgcttat
     7441 ctgaaacatt taaattcgaa aacttcaatc caatatctaa attaaaatcg attgtttcat
     7501 attcaatcaa cccaaaatct tgaaaaagaa aagagagggc atttcttttt atcaagcgct
     7561 tctctcttcc agttaaatgt tttgtttctt gattaaataa ataaaattgc cctgaactga
     7621 attgatcatt caatcctaat atattcaata aagtactttt ccctgctccg ctctctccaa
     7681 ctacagtcac aaaatcccca gcatccgcag tgaaacgatc caaatgaaga atcgttttgt
     7741 ttcgaatgat ttttttcgca ccttttatca ctatcaacgg ctccaattgt taacctccat
     7801 tcatcagcaa taactgactt ttcttttctg tagacaaaat aaaaacaact gaaagaataa
     7861 aatcaatgaa gctaaagaaa aaaatattaa aaagatattt aggctctctt tctataagaa
     7921 aaaggaagat tacacttgtc gttccccatt tgatgaggtt catcatgaag aaatctttat
     7981 acgtttcaaa gagcgaataa ccacttgaac gaaagatagc gattttccga caattgtaga
     8041 caaaatatat gcataacatg acatagctca acaagaagaa agaaaagaaa gtgagtaaaa
     8101 atatctgtat caagtaatga aatgatctgc ttaacacttt gacagctatc tcttcagtct
     8161 gagtatacgg aaatgataac tgcaagttat cacgtaactg actttcttca atcagctcaa
     8221 ataacctttc tttcgacaaa gagcctatct tgatctttaa cggtggatag atttctccgc
     8281 tgagaatatt tctttcccaa tacgtactgt ttttcaatgt cagtatttca acaaccggat
     8341 aatgttcgat ccaggggata gaaggaataa atgtataaat gggttgattg ttttttataa
     8401 atagaaattt cggttctttt tcactgattt cttgataata ttctgttatt tgcgccaggt
     8461 cattttttaa atctgtatgt ctatatcgtt cagggatcaa tataacaggg tgcgtttctt
     8521 tttcggttat ttggatcaac cttccagaga catcaatcaa aggaaatttc ttaagataat
     8581 tcagatttat ttttatccct ctgccaaact gttcattttc ttcattcaag taatctgata
     8641 cattgactaa tatacttccg tttttattca aagtttcata taattcctga tcggctgctg
     8701 atgcaaaacg attggaataa ataaaatcca cgtggttttt cccgatggtt actggataaa
     8761 atacatgata gtcctcacca gcgatttctt ttggtgtttc atgggaaaca gctaactgtg
     8821 aagaagaaaa aacgatagtt gctaattcga cattggcaac ggtcaaaaga agagaaaaca
     8881 acaatccaaa tgtaaaaaga atgtattgga tatagttgaa cgcttctctt aacgaagcga
     8941 ttttttcaac taataaaaga gaaatcaaag agatacccta tattccgctg aacaagaaaa
     9001 cgtacatctg gaacaaataa agaaattgct ccttataata cataaaaata aaaccaccaa
     9061 tgattcctgc aattatgaat gtaataatga ttttcttttt ccccaataaa caccacaata
     9121 cttgatgtaa tgaaaagcca ttattcaaca ataaactgat ttctttattc atcaataaga
     9181 aaaaggatga taacaaaagg aataaaagaa tcaatccaat agttaaatac actcgataat
     9241 tatatacgtc tgtacttgaa ataaccgaat acgaatagct attttcaaag tcttcaaaaa
     9301 tattagtggc ataatcagtg tgaaatgctt gattgaatcg ttccacaaat agtaaaatga
     9361 accgttcata ggcttctttt tctctcgtca tcaagaaaaa ttcaccttca aaatctttta
     9421 ttttgatcga ttcttcaatg gacgttacgc gaaaggaggt attagaatag ggtaccttct
     9481 cgtgagaaga tttgacatcc ccttgataat acaatgtcat ttcaagcttt ggctgtatct
     9541 tgaagttcca agatgtatct acttcattgg attcatttac tgtttttttc atataagaaa
     9601 gctcagtttc tgatgagaca ttttcaaata ccatgattag ctgctcatat tcttcttgcc
     9661 caataaaatg ttgtggcaat cgaatcggag tataagtatc tgtttgatgg aaaaattcat
     9721 ttgtccgata gagtacctgt ttatttataa taaccaaggc aaaaccactc atgataccgg
     9781 tcactatgat tgtgagtaaa actgtgaact tttttttgat tatcaccact ctcccttact
     9841 taaatgattc tttgataaaa tcataccgtt tttcatcaaa aaaacgtatc tatcaaatgt
     9901 ataggtcatg tagaataaat ctatatactg tagaatcgaa aggagaagaa gatgaacatc
     9961 ggagaaaaaa tacgaactta ccgcagaaat tgtaagctta cgcaaaaaga attaggcgaa
    10021 aaaatcggtg tttccgataa aacaatctct agttgggaaa attctcgtac aatgccagac
    10081 cttgaaatgc tgtcactttt acatcagact ttaggtctgc cgattgattt tccttctatt
    10141 gaatcagcta ccgaatcaat agaaccaaca ttgccggatg aacctcttgt tatcaagaaa
    10201 tcttattcat caaaacaacc cttctcactc aaaaagacac tatctttctt tctgctcgtc
    10261 ttttgtttgg tctatctttt tcttatcaat tatcaatata aaaatgaaac ggttgatcga
    10321 ttcaatcctt ttttgaaacc acaaatcggc tataccacac tccctgtagg atacgtggaa
    10381 aattccatcg aacattgggt atgtaatgat atctttgttc atggtacatg gctgtctttt
    10441 cacgctggag aggtagaaaa aggtaagaat catgctgtaa tcaaacacaa aggaaaacac
    10501 gtcatgaacg ttcgcctgct cacttgggaa gccattccct cagattacca agaaatcctc
    10561 atccaagact atgacgatgc cttaaaaaga agccctcagg agccagatag gcattaagta
    10621 ggagatgaac gtagagatag aaaaaatcaa tgcacatgat cttatcaaaa aaaaacaggg
    10681 gtacaaatta attgaaaaag ctttgagatg aaagttccta aataaaaaag ttcagaatga
    10741 taggtaaaaa aatgactaac tattctagta ttaggctatt tgtattattc ttctgttatt
    10801 tttatatcaa aaaatccaga aataactaaa tataggtatt tctggcttat agtataatat
    10861 ttacgccaca gcccccaatg attctttttg gaatcatgat caaggacgga catacacaaa
    10921 aatattttgc ccattcgatc cgaatagatt aacgactaat ctagtaagta atatagattg
    10981 gtacgtagtc aaaccagcaa atggaaaagt tgtctattcc accccaaggg ctttaaagac
    11041 agcatcttcc ggcgtttgat aaaaaatcaa attaaaggta cccattaatt ctgggggtac
    11101 agttccaata tcagcagcgc ttatcatagg tacaagtact tttttcgctc cggcatcttt
    11161 tgctacttgt aaacagttag ctaaattatc taccttaatc atagaaccac caattgtaat
    11221 atcccctaaa ataactaaac ttggtaatac aggtttattt aaggaaactg agcataaagc
    11281 tattatagtt gataacgata atgtttttgt cataccaatg ccattcatat cttgaacatg
    11341 aacgacaaaa tcttttgtcg tcaaactaat agactgacta acacttccat aattagctct
    11401 taaatatcgg tatgccgaat ccatcgcttc tcttgctcca gcatctgaat tgatcccagt
    11461 acgttcaaac tttccatttc ccgaagtcat ttgcgtttcc aatttatagg tacctaattg
    11521 cccagttttg ccataagata ccgtgtacaa atgccctggc ttccctaacc cttctggaat
    11581 caaagttcct ccaccttgtt caggaacaga aacatactct tctcgctctt cttctaaatc
    11641 aatgtatgaa aaattgacat cataaaattc cattccacca attttcttta attgttcttt
    11701 tacacgacga cgcatttcaa gagcaaatct tagtatttct tcgacatcac ttttttcaaa
    11761 tctaccatca ggatacaaca gtttcatcat cccagataca atccgacgaa ctgcaatcgt
    11821 atcccgctga tttaattgag aaccaagttt gaaatattta tcaaaactat cgccaaaact
    11881 aacttttcga agctcacgca tgacttcaga aaaataatct gtaatgaagc catagtcatt
    11941 tgtaaaaaaa tctggtcgat atttaggaat ttcccaacct ggtaaataac aatgcatccg
    12001 atccaaaaag gctgaatccg tccccataac ctccggaaat ggctcaaata aattcgaagt
    12061 tttcaatatt acatcaacgc tttgattaat atttcctaca aaagccattg atgctgaagc
    12121 attcttttct tctttgcctc tagcaaaaga tcctgaagcc atgtaatctt tcatgatttg
    12181 aacgccatca ttatccttaa atttaatccc agcaacttcg tcaaaagcaa cacagtccca
    12241 catacctaca agtcccattg tacgactagc catattatag aaaaggtttg ctactgttgt
    12301 ttgtccacct gaaacaagga ttgagtttgg tgaaatttct ttatatacat gcgatttacc
    12361 tgtaccacgt ggtcctagtt cacagagatt aaaattattt tcaattaatg gaataagtct
    12421 tgctaaatga agccatttta cccttttatt aaattgtgta ggttccatac caatggaccg
    12481 tagaagtaag tcaatccatt catttgtagt aaactccttg cgagccatct tgtaagcctc
    12541 aatgtctaaa ccaggcattt ggattggatc aacctttttt gcaataaaag ggctattcca
    12601 acgatcattc tcatcatacc aatattccat cgaaacaata caccagatcc ccccacctaa
    12661 taatcgatca aattttttcg gatactcttc actaatttga acatttttta atcccaggtt
    12721 agagaattct gcttcataac aatctttctt ttcatttaaa tgtacagtta ctttatcaat
    12781 aactgtataa ccacccaatt cacgaatttt tgcttttact ttttctgctt catcaggacg
    12841 cacatagttt cgagcaagaa tatttttaac attttccaca cctttttcaa ccaatgtttc
    12901 atccaatgac gaagcataca taccaagtaa atattccaat acataaacag gtacattcgc
    12961 accttcttta attttctttg ttaaatcttt tctgacaatc tttccgggaa agaattcaga
    13021 taactttaaa atttcctgtt gttccactag aattcctcca tgtgttcagt cattataata
    13081 gcaattaaag tatatcatac ttaaccagta ggcttgataa tacaaaagaa aaagtatcca
    13141 caaaaaattg tggatacctc gtttttatat atcaaaatca aatgattctg caaaaggatt
    13201 atctataatg aattttattc gctcggtcaa atcatttttt tgatttttta tcactaaata
    13261 ataagtatct tcaactgtat atcgacgatt tacaaattca aaaacaaatt tagtaaaccg
    13321 ctgatttgca tcttctgttt ttgaatccgc aacatagatt tcttcatttg agatacgttc
    13381 accatattca tcttcaaaat aaagccagaa agatgcgggg tcataaacat cactaattgc
    13441 atttttttga tagaattcta acgtggttga taatcctgta attctgcggt tgctagtcat
    13501 taattcaatt gctactggtt cctttgcatt gctacctttg gctaccgtaa tttctagaac
    13561 agggactagc atttcttgaa tagatgaccc tccatgaacg tagctttgtc ccccgccagc
    13621 tttcttaaaa atacttgaag taatcgggac acaaatgttt ctagtgtcat catttcctaa
    13681 agaatctccc aaagagtaat ttttcgtacc aattatttcg tattcttctt cactaagaat
    13741 aaaacgacgt tctacacgat ctttttcatt tctagatgga ttttcaatct tatctacttc
    13801 ttcaacgtgg cttcttttat aaataaatcc atgatcagcc gtaactataa aacgatagat
    13861 actgccatca ttatgcaagc gattaataag tcgggaaatt tcgcttatcg ctaaatcaca
    13921 ggcctcaaaa actcgatttt cattcgagtg atcacctgtt ctatccactt gatcgtgata
    13981 aatataaatg actgatttgc cattaaatac ttctcgtacc tcagccttat tcatcttaac
    14041 cacatcatca taatttaaag ctacagcatt tgcatctcgt tgctggagaa tcgcatttcg
    14101 attggataaa ccattcgttt ttttcccatc aatcagtact tctgttcctt cattgtaagt
    14161 tagttgattg tttggtaata aggcggcttt accgaattca gtaactgaag gtaatacaga
    14221 aagaaagcta gccatgtttg ttgaatactt cttttctcta actaacttac gttctaaatt
    14281 catccctaac tcatatcgaa aagcatctga aataataact acagttttaa cagagcgttt
    14341 cattacagct tgattataaa attttcgaat ggatggacga ttcttaaatt caaaagtttg
    14401 attccaaatt tgtcctgatt gatcaagaaa cttcgaataa tttgcttcaa ctaatcgata
    14461 caattggcca tatttttgct tttcttctat atgatcacta ttccaaataa atttccgata
    14521 atgcgtatca acccaataca tttccttctc atattgagtt agcaaattat ccatgttcat
    14581 cggcaagcac aatctgtttt tatccacaag ataataagca tgtttcaata attgatactc
    14641 ataaatataa tccgatgcga aatgcatttt ttcgcgctgc tttaaactat caaaaattgt
    14701 ttgtcctgca attttcgttg tagtgtcaga agcctttaat cgttctgcat aaaacattaa
    14761 tatttttgca tgaatctcag aaaatacgtc tgcttcaatt agatcatcaa tttctatact
    14821 gtctaataat ccatcaccat caatagcctg atatactttt ttagatagct gttcaaagct
    14881 ttccatgtaa cgtgtatcat tcataaactg atccatgaaa gtaataatgt ttgctttcaa
    14941 atgtagtatt tcaaatcctt tgaacttctt cggcatctct tgatcaattt gataataaaa
    15001 atagttcaaa taaagacaca tcgtcagctt ttccaatgtt ggctggctat ccgtaaagcc
    15061 aaatttcatt tgaataaatt cccaaaattt agctgttaac tgatacttat caagttccct
    15121 taaaggattc tccctacttt ctgtaaagct ttttagaact acacgcagta aatcatttaa
    15181 tcgaatactt ttcgatttca acaaaacagc cattatcatt aattcaatcg tttctgattt
    15241 attaattgtc atatgcgtac taaattcacc aaaacttctc atgcgatcct ttgcattaaa
    15301 gaaattacga tactgtttaa ctgtctgatg aaatctaagt ggaatagcca attcattcat
    15361 gataatcgct aagcggtctg cactaaattc ctctgaataa ttcaatacac tcaacaaatg
    15421 attatcttca tctttatcat cccaacgagg aaatggcgca tagattaaat agttagtttc
    15481 gggatcttca tattccaata aacgcttagt tttaaattgt gcgtcctttt ctaatcgata
    15541 gatttttgca ttttgaatga ccaatgagtc aatttcttca agaaaatcct gatttgaatc
    15601 aaaccaaaaa atgattttcc tacatccata attaggaaaa cgttgattta atttttcttc
    15661 aatttgttgc gtatttatat ctgtcatcaa tctcacctaa tcgttctctt tctatacccc
    15721 ttatattgac ataatttgga taatttcgca cgcaatttaa gaataaaaaa gaaagttgtt
    15781 agaaaacaac tttcttagat aactattttt ttggttcttt gacccctttt gcaaaaattt
    15841 ggaatttctc gccggtttta ggatcacgct gcaacttatc ataattgaca attacaccat
    15901 catctaagtc taattcaatt cgttttaatg ctaagtgacc caacttctcg tcatactcac
    15961 gaacttcttt taattgcttc tgaatcttta caatttcttt tgtcattgca tttctttctt
    16021 ttgggttatc acttgttgaa atttgttgct gacgcaattc gattcgattg tcatacgctt
    16081 tttgtagttc gtgtaggtat tcagtacgta cttttcctaa ttgatctggt gtatagcgat
    16141 gcaagtacat taacgcttta aagccatttt gttttcctga gtccaattgc caataaattg
    16201 gtcgattgga gtatgttttt aaatggtctt tgtaaaaatc ttgtacgaag taacgacgaa
    16261 taatttctcg acttgtccct ttgccaccta aagtgtcagc gataaactgg agattttctt
    16321 caagggtttc tttaccaaaa gtaatctcaa cgaaatcaat gaaacgattg acaatgtcaa
    16381 tttggctatc cttgaaatac tcatcatcgg tgatgagtaa aacattatca gtatcaggtt
    16441 taaatttttg atagcgggaa ggatcccatt cgccgccagc gaagatgaga ccatcttcgt
    16501 ctagggagta acgaccgaag atacaaccta ttgaataaga aataaaatcc ttaatttccc
    16561 tcgccttatc aggtaacctt gcagagatat attcatcttg aacctctttt gttaattctt
    16621 tttcaagaga ataatgatta atgaatatgt cgttcagttc ctcttcattc gattttagag
    16681 tattaaattg attaaccaac tgcctactta gacagttaaa tgcctctgag agatcttttt
    16741 taaacatata acttaacaaa atgtttcttc taaactcgta tgacgtttca agagcattat
    16801 agtcttttct agctatatcg atattttcat ccactttttc tcttattttt tttaattttc
    16861 tctcagatgt aactttaaga aaaggtagtt ttcccattgg tccttcatgg taatccaagg
    16921 tgggagaaat aaaagttaaa aagtgattaa ctaatttaga gtttacatag ccaaatattt
    16981 cttcaaagtc agttatatcc tttgagaaca gaacagatcc tttagtttca aaaattgcct
    17041 gattctgcaa tctaaaagat acttgtccag atgaaagtgt cgaccaagta attccctttt
    17101 taaaatagta attaagattt tgtggtctag attttaactt cccattttca ttaacataat
    17161 tttttatttc atctccatca ttctcccagt taaccacgta ttcattgttt ccataccatt
    17221 ttctaaaacg accaccttta gttgtaggaa accatttttt tctagacttt ttagcgtcct
    17281 ctaatgtttt agcatcaaac tttattttgt taaattctac ttcaaaccaa taccgcaaaa
    17341 atttattgtt atttccggtt gccaaccctt gttttgcatc tgcaacatcg ttagttaatt
    17401 ttccttgagc aaaatcagtg attacgttat cgcttgccca gtaagcaatc ggcattcctg
    17461 ggattttttt gaagttgtct tgattagtac tataaaaata atcgcattca ccatgctgat
    17521 gaattgcttc taacgtttta attttttgaa cttccattcc acctttaaaa tctgataatt
    17581 ttatatagct tccatcttgt tcatttgaat tttttatcgt aaacgtacaa attggaacgg
    17641 ttgcttcttc aaaagctgaa tactccattt gaatcaaact agaaatgttt ctttcattaa
    17701 ttaaaaatga gcgtaacttt tcatagctag aaatgaacat ccaaacaaat ggcgtcataa
    17761 aggaagcata tccattatca atcagcattt ggctattcaa tttaataaac acagaaaata
    17821 gatctttttt gacatcagaa tagttatcat ttacatattt ttttaatttc ttatccattt
    17881 tattaagata aggcggatta gtgactaccg ctacatattt atcaactagc atttcagcca
    17941 cgtcaagaat gtgcaagtat ttttcttgta tttccttcat cccataaaga atatccatat
    18001 tcgtaaattc gttgaatttt gatatatact ctcttacttt tcctaagtat tctttagtta
    18061 ttgcctgatt atttttatcg actaacttaa tgattgatcc aagttctttc ccattttcaa
    18121 attgatcaaa aattaactct ttgtattcat tccagcgttc actatactta tcattgttca
    18181 attcactaat acgctcttga tactcgtctg tcactttagg agaatcaata aactctctta
    18241 aattcggcga tagacttttt ttcaaaaaaa gacgatcgta ttgacgccct ttcatcataa
    18301 ttgcaaaata agacaattga tacgctcttt tatcgatttc aagaccatat aaattgtatt
    18361 caacgattgc acgtgcagca tcacgctcag aatatcctaa cgtaagataa atttccatca
    18421 atacatcgaa ggcgtaaact aaaatatgcc cagaccccat tgcgttatcg ataattttta
    18481 gttcttctgg ttttaaatta cttacagatg ttgcttgttc aaaagcatat ttatctggaa
    18541 ttaagtattt caacttattt cttaattcac tattgggata atgatctaac caatactttc
    18601 ctaaactatt gtcaaccata taacgaacga cccaatctgt ggtaaatagt tgagttgctg
    18661 ccggaatatc ttgttttttg acaatccctt tataaatatt caccacttga ttatgtggct
    18721 cactattata gtactgatac aaccacccaa taatctctac ctgtccacca gcttgaacat
    18781 agaaatcatc ctctggaata cttaaaagat cagcgattac accatctttt ttaatataag
    18841 aagctgtaaa caaaagttct gtataatctt ctacttcttc aaatagctca ggtaagtaat
    18901 cattcaattg attacagatt tttataaaaa tcaattgata cagcttgtcc attgcttctg
    18961 ctgaattatc tgttttccaa gttctgactt gttgctgttc attactagat aattcttcaa
    19021 agatatcggc atcataaata tctgtaataa tatctggctc aattttccca cttatttcac
    19081 tagataatac acgatacgtg tcaggtaaat aatcatttac ctccataaac cgaatggcaa
    19141 tcaatcggtt aaaccacgta taagcaacct cttcgattaa ctcttgaaaa gcttctgaat
    19201 aagaagtgac agaagcacgt tgttttagtt ctgcaatcaa tttgtttctt tgcgctattt
    19261 cttttccttg aattcttatt cctgattttt cgatttcttg taaattgcta tcaattttct
    19321 tcacatcttc aatttttgat tcatcaattc ctaaacgttt tgctttagtc attacttcat
    19381 caattaattt tctacgggca ttgaccgcga aattctttat cgctttctta tccatttttc
    19441 tttcccttct atatgtaacc tttgaaaaga caggcacctt tttatgcctg tcttttcact
    19501 agaattgaat cgtgatttct gtattttctt gaagttgttc cttcagtttt tgattaattt
    19561 cagctgttaa ctcatcaata tctgctgctg acttaatagt tttaacatga acgttaagtg
    19621 ttctcattgg tactgttttc tgttgaatag taggttttac tatcgctatt tcttcagctt
    19681 ttgctgcaga gtctatttca tctttttcag tttcacgaat caagtttgct gcttcaattt
    19741 gtttacgtgc ttgttcttct tgacgtctgc ggttttcttc attatcgaaa cgttgattaa
    19801 agatcaaata ctgttctgct acgtttaatg ataagaaaac aagatcatct atagtattcg
    19861 cttgttcaat ttttgctttc agttcttgaa attcttggtc aactattggt acaaattgat
    19921 ccttaaaatc ttttccttct aataatttaa atgttgcttg tttttcttcc gttaatttat
    19981 ttaatatttc ctgactttcc aactctaaca gttgattata ttgttcaata aattcttgaa
    20041 tcaactcatt tagtttcatc atatctgaat aaggatcagc ctttttcaaa atggttttca
    20101 tctcatgaat caattgatca atttcttggc tagaagtttg acgccgactt ttttcgatta
    20161 atctaatttt atcttgtgca ttctcccaga tttttttctg agtactattt tgcttgtgga
    20221 aatttttaat tttatcatat gtttcagccc agtcgaataa ttcatcgcga tattttttga
    20281 ttgtataaaa aaagtcttca acatctgacg tttgaacaat tacttcaaga tattttttta
    20341 tttgctcata ttcataagca ctagggtagg tataagtgtt ttgtaaatca aaataagagc
    20401 gtaaattgtc taattgacct tttaaatatt tcttgaaatt ttccattgta tgttcattgt
    20461 tattttcatc aacaatatta cgactttgaa acagttctct accgatttcg tcaaccaatt
    20521 tttttgcttt tggcgaaatc accgcgcttg gttcaatttt tatcttttca ctttctcgtc
    20581 gtttttgaat aatcattaca atactatttg gatcatccat ccgtgaaatt tgtacattgt
    20641 tataaagtaa atcaatttta ccagacatga aaagtttagc gatgcaccat tccacatcaa
    20701 gttctgtgaa tccatacggt tgttttgttt caaaacgatc acgaattgtt ttcatcgtaa
    20761 tcgttaggtg atttctcttt tgatcattga taaaattgaa aatttcctga actgcttgct
    20821 catttgatgg atcttcaata atttcatttt tgctttcttt cactaaatat aagatatctt
    20881 ctttttcttt aggcgcatca atttggttta atttatggta tacttcttca gccattttct
    20941 gaagtgctga ttggaatttt gctttaaagt cggagcctgt cagttgaatt tctgcaccgt
    21001 tatagaaaaa ttttgcagat ttcaacagtt catttaattg atcgttgata cttgcactta
    21061 gttcctgtaa ttcaccagat ttttccgaac gaatcgcgtc aaagttcttt actacactcg
    21121 aataagtcgt tgttaaataa agattcattc tagcatacat tgctatatca tctttaaatt
    21181 ctttatctga tggcaattct acgaataata agttacggga actcttaagc gcaagttctg
    21241 cctcttgacc tgctaaatca gagtatggtg aaataaaatt aactgtcatt tcagcatttc
    21301 cagcttgctt gtatggacgt tgatctaaca cttgtgcata agtaaacgta taccggtttt
    21361 taaatttatt tccacctgac atgcctaatt tttcataggc aaaactattt cggtctagaa
    21421 cgccgtcaaa aattcgttta gatagttcta cgatcaaatc actatctgta atattttgat
    21481 ttttaatctc acgagtaatt tcctgttctt catcagtttg gaaaatataa ctatctaagt
    21541 tcttccgcac aaagttttcc ttaattaaaa ggtccaatgc ttcttctact cgttttttag
    21601 tttccaggcg gtcttcgttg atatttctta tcatcaagct cgtaatattt tcaacatttg
    21661 gtttgatggc ttgatcaaca tatttaatca tgaataaaat tcgtaagaca tttacgttaa
    21721 agttatctat atcagttggt ctttgaatat gagaattatt tgtagcttgt gtaatcactc
    21781 ggctaattgc tgtatcaatc caacgttcta acgagtaata aaactgatct aaagaaacca
    21841 aactggttgt atcattttcc ttatttcgtt cagcggcttc tttaaacatt gctagtaatg
    21901 aacgttcacc agacgataag tttgatcctt gatagctgtg attacgaatc tcggttagaa
    21961 tttgccccaa taaattgaat tgatagggaa taaatggata aacttctgcg taattttcag
    22021 catcttggaa gagctttaat tcaggactat caacaaagag taatttattt ttcaattctg
    22081 tttgaacagt ttcaaattgt aaggctaaag aatcattggc aaactctttt ttcttcaaaa
    22141 tacgttcttt aattacttca tcggcatttg ctgaagataa actcacagtt gtggcaaaac
    22201 gatccttgat cttagaaaaa tcattatcag aattgttatc aaagtttgtt acgtgatcaa
    22261 tcgcttcctg acttgtcact aatacccaag ccttaccttc acaaattcga cccaaatctt
    22321 ccacaacggt ttgtaactgc aaagtcaact cacgattacc gccgatatat tgtccgacct
    22381 catcgactag aaaggcaata tgatggtctg cttctttgga atcaagatag cttttaacta
    22441 gatttgcaaa gtcatcaatg cttattaaat aatttcctga tgctttttct aaaaaattat
    22501 caatagcggc ttcactcata aaatcgattt taagtgccgc ttctttgata tcatcttgga
    22561 tccaatcaaa ctcatggcgc tcttcttgcc attttgcccc attaatctct tcaaaagcag
    22621 ctttgaatgc atcaaacttt tcttctttaa ttaaccgacg ttcaaaatct gctagatgtg
    22681 gaatcgtgct taatccttgc atttcgttaa atacctttaa aaaaacattc acgattccgt
    22741 ttttgtcttt tttaccacct gcatcacttt ttgaatcaat attaaacaga ataacatctg
    22801 tatttatttg tgagcaccgt tccatcgttg ccaaagtcag tggatctttg attttcccat
    22861 cttctttgaa gtaatcaatg gctttcttgt catttatttc tcgatttgcg agcaagtaag
    22921 aaataatttt taagaaatga gatttacctg aaccaaagaa cccctgaatc caaacaccca
    22981 ttttatctgt tggtgtattg atactccgtt ggtaggcatc aaaaattgtt ttaaagtgtt
    23041 tttgtagttc tttcgtaacc acgtattctt ctaattcttg ttgaacattt tcatcctttg
    23101 cttgaccgac cttaataact ccttgaatat ttcggtcaat tggttttgca aaaatatctt
    23161 taattagcat ttaatctcct accttccatc ccaactaaat tctaaatgct cgataataat
    23221 tatcatcttt attggtatta agaattgtca aacttaattc atcatattcc cctggataca
    23281 tcatcacaac tggtacgcga tcaaatacct gatgcatttt atttaaaata gagtgcgctc
    23341 taattaatgg atataattcg ccaattcctg tcaggaacac aactgatttt tctggtgtat
    23401 gggcatccac atattcaaaa aatacatttt cttcctcagg taaatccatt ttcaataaac
    23461 gaccaatgct ttccactaat ttttgtaaac cacgtcgttc ttccatctta atcgcttttt
    23521 cagtgaaacc gcgtttttct agatactcta acataatcac atagagatta taaactttca
    23581 cttcataatt atcaccaaca gatgttccag atatatcatt aatataatct cttacaatta
    23641 actcgtcttt cggatcgtag tcaaagatat aatagcctac ttcattacct aaaccacgat
    23701 tcaataaaaa atcttctttt tgaattactt cattcaactt ttccaaatgc tcttgaatcg
    23761 ataatgacat tataaaattc ctcccagtgc tagtacaata tctttacgat tcttgtcaac
    23821 taaccattga atcaatcgtt tatctaataa tatcggagtc attcgtccat attctttttc
    23881 ccctctgact aatcctgttt caattagatt cgtttgataa gcggcaataa gccgtttaat
    23941 cgtataatct ttccattttg aaatatcttc tgaacttctc cgcttctctg taaaaaaaga
    24001 acggtaatca actggtgtta attgcaaatt tcctttacgt agattttcag catatacctc
    24061 agtcataaat tcattaaaaa gatcatcaat cataaggatg gaaatcaaat tcactaactt
    24121 ttgattatct atatttaact gattgaaaag ttgcaatcca gcttcatcca gttgactaac
    24181 tctccttttc acgttctgat agatttcttt ttgacggtta ctgctcactg caaaaaaaat
    24241 attttcatgt tcatttttct ctttaatttc tatatctgta tatccttcta gtcgtaattg
    24301 aatatataac ttgaactctg aaaaccaaaa gcgtttagaa actagaccag cagaatattt
    24361 tttattcaat agattgcctc ctaatcatct ataattcaat aagtaaacaa gtgttttttg
    24421 ctcatcgtta gcattcattt tttagtatct actatacaat acatatttat tatag
//
LOCUS       DAZKKZ010000045        24434 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.046, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000045 DAZKKZ010000000
VERSION     DAZKKZ010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 24434)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24434)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24434
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.046"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(53..787)
                     /locus_tag="ACG8LA_001892"
     CDS             complement(53..787)
                     /locus_tag="ACG8LA_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MIP/aquaporin family protein"
                     /protein_id="HFQ0204187.1"
                     /translation="MDYSLMTRLAAEMIGTALLIVLGNGAVANVDLKGTKGYGSDWML
                     IAVGYGFGVMMPAMIFGGISGNHINPAFTIALASNGLFPWAEVVPYIIAQLIGAAIGQ
                     LIVVACYKPYYDQTEDVNHVLGTFSTINSVGSKFNGFVNEFFGSFVLFFGALGITKAP
                     FFQDNLGTAHLALGFLVWTLVASLGGPTGPGLNPARDFAPRLVHALLPLKHKGSSQWG
                     YAWVPVVAPICAGVVAVFLYKLLFMA"
     gene            1114..1524
                     /locus_tag="ACG8LA_001893"
     CDS             1114..1524
                     /locus_tag="ACG8LA_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HFQ0204188.1"
                     /translation="MKFFQEFFIIIFFSVLGEGIRIFAHLPIPGSILGILFLFLAFEM
                     HLVDPEKIGATGDFLLNNLAILFVPAGVGLLEYFDDIASIWPVLLGAVVVCSIVTMVA
                     AGKTAEGVEALLGYVRKKKAERVSVNEMEENQID"
     gene            1517..2218
                     /locus_tag="ACG8LA_001894"
     CDS             1517..2218
                     /locus_tag="ACG8LA_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HFQ0204189.1"
                     /translation="MTEFFVNPLFGLSLTLGVYVLSDKFLRKYKLPVLNPLVLSIVVI
                     ILFLHFSGISYKDYNIGGNFLTMLITPATVALAIPLYKNFRLLKENFYPVMAAILAGI
                     VANCLVSVGFGYFFSLHKEMVISLLPKSVTTAISVDLSHTMGGVNAVTLAIVVSTGIF
                     GSLIATHIFRLFKIESPVARGVALGSTSHAIGTAKAIEIGEIEGIISGLAICVNGILT
                     VLLLPLFFQPFAGLF"
     gene            2218..3804
                     /locus_tag="ACG8LA_001895"
     CDS             2218..3804
                     /locus_tag="ACG8LA_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0204190.1"
                     /translation="MRKPLFYATITKTFEHKKGGKDVYLSSEYLKQFDKDLYYKILLL
                     ESFEDQAWHTAAQLAQVVQLDARSVSKYLNELSKNYQQFSGKTHPLFTKNHRSGYNFY
                     DTLDSIEHERFLIYLVQSTLKFQLLHDIFFEEFHTMYQFAQKHYISESTAHRKINEWK
                     QQLQTYGIRLQRGTYIAQGEEEIIRLYLHMTFWQLFRGKIWPFETISQMDVKNMAEHI
                     MAFFNVRLNEIKKRRLEYMLGAFFLRKSQKHYVVLNEKKRRLISDNLLFQRFCQVMEP
                     VFPNYFQVEDELGALFLVLMTREEYYSDPKIRKKIFDFHQQAKTPPFTALSEAKAALS
                     LYQEEQGLPAENLTFEAENYLFSSHFFAYLFPNAKETIDGNSSDFINHLVIENKELKQ
                     WLVHFFESRHKHPNHLAFKNHAFLMGRYLTVFKTLGAFTPQLPKITILLMTDFPLFEE
                     QLLEEGLRTFFRNEYQLIFLPTDYRGREVDLLISTSKVHRKPWADLDYFIVTEELKLI
                     DYIQLSQKFEMIQKQKLLKQ"
     gene            3823..4044
                     /locus_tag="ACG8LA_001896"
     CDS             3823..4044
                     /locus_tag="ACG8LA_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HFQ0204191.1"
                     /translation="MTFEEILPELKKGAKIIRKGWSGFELYVVLVSDDEFDGCPVTPY
                     LLIKTSDEGFSSFAPTVCDILADDWAIVE"
     gene            4041..4802
                     /locus_tag="ACG8LA_001897"
     CDS             4041..4802
                     /locus_tag="ACG8LA_001897"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HFQ0204192.1"
                     /translation="MKNQYPDLAKQVVFITGAASGIGAAQARAFLEQDAFVFGLDQKF
                     GKMEEISLRFPETFAYALGDVRQMKELQQAVSKCQNHFGEVTILLNTAGILDAYKPLM
                     ETDESLWDLIYETNVKSMYQLTKIILPDMIRQKSGTIINMASIAGLIAGGGGIAYTSA
                     KHAIVGFTKQLALDYAGQGIRVKGIAPGAIQTPMNAADFEGKGEMAEWVANETPVKRW
                     AQPEEVAELTLFLASPQASYIQGTIIPIDGGWLLK"
     gene            5182..5691
                     /locus_tag="ACG8LA_001898"
     CDS             5182..5691
                     /locus_tag="ACG8LA_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HFQ0204193.1"
                     /translation="MEKNNTRSAKRWTTTDVTRMALVTGLYVAVTLVLSVFSFGVIQI
                     RLSEMFNYLSLYNKRYIVAVTAGVALANIASPLGLIDVAVGSVSTLLVLLINYKITSR
                     IKNMKIKMAVTACVFAFSMFTVAGQLTILYQLPFFLNWWVIALGELASMIVGGIIIYW
                     IGKKVDLSK"
     gene            complement(5766..6305)
                     /locus_tag="ACG8LA_001899"
     CDS             complement(5766..6305)
                     /locus_tag="ACG8LA_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HFQ0204194.1"
                     /translation="MNRTLKELILAAEFAAIISVLSQMTIPFGLVPLTGQTFAIGLTA
                     TFLGRKLGLISVGVYLLLGLIGLPVFSGMTGGIAVLFGPTGGYLIGFLLQTWITGWMI
                     ERTDAHYLYAIFANLMGSLAALICGTIWLKISGDLTFTTAFASGLLPFLLPEAIKATG
                     AAYIGILMKKRLNRFLHTN"
     gene            complement(6445..7056)
                     /gene="rpsD"
                     /locus_tag="ACG8LA_001900"
     CDS             complement(6445..7056)
                     /gene="rpsD"
                     /locus_tag="ACG8LA_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HFQ0204195.1"
                     /translation="MSRYTGPSWKISRRLGISLSGTGKELARRPYAPGQHGPNSRGKQ
                     SEYGMQLTEKQKLRHMYGMNERQFRNLFVKASKIKEGKHGVNFMILLEQRLDNVVYRL
                     GLATTRRQARQLVNHGHILVDGKRVDIPSYHVEVGQVISVREKSQNIVTVKEAVEATV
                     GRPAFVSFDAEKLEGSLTRLPERDELYPEIDEALVVEYYNQSL"
     gene            7318..8169
                     /locus_tag="ACG8LA_001901"
     CDS             7318..8169
                     /locus_tag="ACG8LA_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015499 - formate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015724 - formate transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HFQ0204196.1"
                     /translation="MRGYVQMEKSEGSLRRKSMNPVSPLFEKIDASIEKKANLFENSF
                     SRYAVRAVLACLFLTLGTAVAFAIAMKGEDIAHGLGKILYAFMFSWGLVMILYMNAEL
                     GTSNMLYMTVGVFRQRLALSKAAKILFACIFFNMIGGILCGFLISMTTPFQDLTLDNF
                     MLESIAVKLAKPSATILVEGMFANIVVNTAVLISMRMKEDVGKVITVVFIIFIFAFLG
                     YEHVIANFPAFTLTYFASHGQMDGMTVSNVLHNLFFALAGNYIGGGLVMGLGYAWLNQ
                     SKSSYVD"
     gene            8197..8832
                     /locus_tag="ACG8LA_001902"
     CDS             8197..8832
                     /locus_tag="ACG8LA_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HFQ0204197.1"
                     /translation="MEVLVFPKNEEKALQMEKYMKNLFSFAGVPKPERALLQQPLLDE
                     SKNLSISEVLAFVHYYYEQIEREYQYVAIDLVQKNIKRLTFEDLVVLLPLVQKKEWWD
                     SIDSWRKVYSTWCKAYPEQREEVFQLFEKKEDFWLRRIAITLQLGYKQQTDTGLLIRA
                     IDEDRQTKEFFIQKAIGWALRDYSKTDADWVKRQLTTDLSKLAVREASKYL"
     gene            8852..9625
                     /locus_tag="ACG8LA_001903"
     CDS             8852..9625
                     /locus_tag="ACG8LA_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFQ0204198.1"
                     /translation="MRRKLFAFDIDGTLLDSNKQALDSTREALEKLRKAGHLVTIATG
                     RSRFHAQEIIRDLDFTNYILCNGAAGFLDHEQVYKNLLDRDQLDAFVQEAHHEQIDTA
                     FVSLDNIKRSSSNDVTVMEEAMHSFGAVLPELDQFFAEEQEIYQALAFFDQTYDGKFS
                     SYDKIRFVRWHENSVDVVPKNGSKAATILHLAEQVGIPHEDIISFGDGQNDREMLRMS
                     GIGIAMGNAVPEVQAEAKMVTDTNDQDGIWKALKELSVI"
     gene            10033..10830
                     /locus_tag="ACG8LA_001904"
     CDS             10033..10830
                     /locus_tag="ACG8LA_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00282 family metallophosphoesterase"
                     /protein_id="HFQ0204199.1"
                     /translation="MRVLFIGDVVGSMGREMITEYLPRLKKKYRPQVTIVNGENAASG
                     RGITEKIYKKFLQDGVDVVTMGNHTWDNRGIFEFVNEAKKMVRPANFPEGTPGQGMVF
                     VKVNQVELAVINMQARSFMVDLDDPFRKMNELVEEARKRTPIIFVDFHGETTSEKQAM
                     GWFLDGKVSAVVGTHTHVQTNDARILPRGTAYLTDVGMTGPYDGILGMRREPVIEKFL
                     TALPKRFEVVEQGRSILSGCILELDDTTGHAKEIQLIQINDDRPFME"
     gene            10808..11221
                     /locus_tag="ACG8LA_001905"
     CDS             10808..11221
                     /locus_tag="ACG8LA_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HFQ0204200.1"
                     /translation="MIDRSWSRKRGSFLQQEPEIQKEVRKLTKLLRENETIIRYKELE
                     EKIQQNQYLAELREKIKQAQKDAVHFAHYDKPAAEKEAIKQADQFMQEFDQHPLVVAY
                     RKQLLEADDLLHHLTTMIQEEINGQIEEEKHASKN"
     gene            11205..13850
                     /gene="mutS"
                     /locus_tag="ACG8LA_001906"
     CDS             11205..13850
                     /gene="mutS"
                     /locus_tag="ACG8LA_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0030983 - mismatched DNA binding [Evidence
                     IEA];
                     GO_process: GO:0006298 - mismatch repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HFQ0204201.1"
                     /translation="MPQKTKNTPMMEQYLSIKAQYQDAFLFYRLGDFYELFYEDAIKA
                     SQLLELTLTSRNRNAEEPIPMCGVPHHAAQGYIDALIEKGYKVAICEQVEDPKTTKGM
                     VKREVIQLVTPGTVMDSKGLSAKDNNFLTAVVSQGNEFGFAYADLSTGELKTARLHDE
                     EAVLNEASALQTKELVLGSEITDTLREQLSGRLGLVFSQQNEMEENAEFSFLTSELVD
                     PLEKEATGKLLTYLSVTQKRSLAHIQKAVEYQPDHFLKMDYYSKFNLELSQSIRTGKK
                     HGTLLWLLDETKTAMGGRLLKQWLDRPLIQAKQIKARQEMVASLLDSYFERIDLQSAL
                     TKVYDLERLAGRVAFGNVNGRDLIQLKTSLEQVPMIRGLIEGIDQGQWQSLLSEMQPM
                     DHLVQLIDQAIQDDPPLQITEGNIIKDGFNEQLDMYRSAMRNGKKWLAELEAKERQET
                     GIKNLKIGFNRVFGYYIEITKANLGNAELEKYERKQTLANAERFITPELKELETQILE
                     AEEKSVDLEYQLFLAVREEVKKAIQPLQVLAKAISAVDVLQSFATISERYQYVRPELV
                     SDKHQLLIKDGRHPVVEKVLGHQEYIPNSVEMAEDEMILLITGPNMSGKSTYMRQLAL
                     TVLMAQMGCFVPAKQAVLPIFDRIFTRIGASDDLIAGQSTFMVEMMEANQALRYATPN
                     SLILFDELGRGTATYDGMALAQAIIEYIHRHVQAKTLFSTHYHELTVLEKELPQLKNV
                     HVGAVEKDGEVVFLHKMMDGPADKSYGIHVAKIAGLPSNLLERAADILHTLENGDNGH
                     HTVPAEVEEKTKTAKQEQIKPPAEKVNQDHIQDRVKEENQQLSLFSELSENETEVIES
                     LKQINLLEMTPMDALNTLYELQKQL"
     gene            13868..15976
                     /gene="mutL"
                     /locus_tag="ACG8LA_001907"
     CDS             13868..15976
                     /gene="mutL"
                     /locus_tag="ACG8LA_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0032300 - mismatch repair complex
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0030983 - mismatched DNA binding [Evidence
                     IEA];
                     GO_process: GO:0006298 - mismatch repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HFQ0204202.1"
                     /translation="MAKIQELSERLANQIAAGEVVERPASVVKELVENAIDAGSTQID
                     ILVEEAGLRTIQVIDNGEGILADDVENAFKRHATSKIHNRDDLFRIRTLGFRGEALPS
                     IASVSEMTLETANQEEKQGTYLSLKGGEVIEHRPAPLRQGTKITVSNLFFNTPARLKY
                     VKTLHTELANIGDIVNRLALSHPSIAFRLVHDGNKMLATAGNGDLKQTIAGIYGLSTA
                     KKMLKIEGKDLDFELFGYVSLPEVTRASRNYLSTIINGRFIKNFSLNKAIVAGYGSKL
                     MVGRFPIAVLEIKMDPLLVDVNVHPTKQEVRLSKEKELTELISNAIQKALSQENLIPS
                     AADNLRFKKKVPDQPKTEQIEIDLSYAFEEEKPKKPSSLNFDRQTGTFFVEELKNTFV
                     DRIVDKSVENVENYSGFSEENTTYPEKTAKTVDKFGENVDNFVEKTVEKSEKKEFPIV
                     DNMEKTNEEQADKSVEEDEKIYEEELTLHPEFDFTQGNDKTLEQAIKKLETEKPVQRF
                     PQLEYFGQMHGTYLFAQSSDGLYIIDQHAAQERIKYEYFREKIGEVSDDLQELLVPFV
                     LDYPNSDALKLKEQKHLLEDAGIYLEEFGQNSFIVRAHPTWYPNGEEESIIREMIDML
                     LTTGSVSVKKFREATAIMMSCKRSIKANHYLNEAQARVLLKDLARCENPFNCPHGRPV
                     LIHFTNSDMERMFKRIQDPH"
     gene            15998..16558
                     /locus_tag="ACG8LA_001908"
     CDS             15998..16558
                     /locus_tag="ACG8LA_001908"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0047429 - nucleoside triphosphate
                     diphosphatase activity [Evidence IEA];
                     GO_process: GO:0009117 - nucleotide metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside triphosphate pyrophosphatase"
                     /protein_id="HFQ0204203.1"
                     /translation="MKIVLASQSPRRKELLAHIVSEFEIEPADIDETPFPDEQPVDYV
                     RRMAEEKARTVWEQDEKEDHLVIASDTTVVLNQEIMGKPEDLAEAEFMLKKLSGETHT
                     VYTAVVLKTKEREERILAEAHVTFYPLTDEEIKRYLETGDYADKAGAYGIQNAASVFV
                     KEISGDYYSIVGFPIGAVNQALKTFI"
     gene            complement(16643..18631)
                     /gene="treP"
                     /locus_tag="ACG8LA_001909"
     CDS             complement(16643..18631)
                     /gene="treP"
                     /locus_tag="ACG8LA_001909"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015574 - trehalose transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015771 - trehalose transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HFQ0204204.1"
                     /translation="MAKYQADAEKLLHDIGGKENIAAVSHCATRMRFVLNDPGKADEK
                     AIEDIPSVKGMFTNAGQFQVIIGNDVSTFYNDFVAVSGVEGVSKEQGKAAAKQNLHPV
                     QRAIAVLAEIFTPLIPAIIVGGLILGFRNVLEGIQFESLGGTIVEHSKFWNGVNAFLW
                     LPGEAIFHFLPVGITWSIAKKMGTTQILGIVLGITLVSPQLLNAYSVASTAAADIPFW
                     DFGFAQVQMIGYQAQVIPAMLAGFMLAYLEIFFRKYIPQSISMIFVPLFSLLPTVLAA
                     HVILGPIGWTVGSWISNIVNTGLTSSISWLFSAVFGFLYAPLVITGLHHMTNAIDMQL
                     IADFGSTNLWPMIALSNIAQGSAVLAIIFLHRGNKKEEQISIPAMISCYLGVTEPAMF
                     GINLKYVYPFVAAMVGSGLAGMFANLMGVRANAIGVGGLPGILAIQAETWVPFIIAMI
                     IAVIIPFGLTIIFRRQGILNKIDPAVPENAADVQLQTANGATATPQSFEPVSATGTAV
                     ATKETLFAVAAGTIKEITEVNDPVFSQKMMGDGYAVEPSNGKVYAPVNGKVTSVFETK
                     HAIGILSNEGLEVLVHMGLDTVELKGVPFNVFVKEGYLVTPETLIAEMDLPEIEQAGK
                     KTDIIVALTNNEKVAGLSLDQSGLVRPGEAVGKAEVKS"
     gene            18854..19567
                     /gene="treR"
                     /locus_tag="ACG8LA_001910"
     CDS             18854..19567
                     /gene="treR"
                     /locus_tag="ACG8LA_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HFQ0204205.1"
                     /translation="MNKFNEIFLDLEQKILAKEYPPHSLLPSENQLIKIYGVSRETIR
                     KALNLLTTEGYIQKKQGKGSIVLDRNRFDFPISGLTSYKELQETQRIPSETIIHTLEE
                     TEVTKALNEITGWEIGAPVWHLIRERKINGEVVILDTDYLLKEIVPILTPAQAQGSIY
                     EYFENELSLTIAYAQKEITVEEVTEIMKTAMDLHDDTYAVVVRSLVHLEDTRCFEYSE
                     SVHRLDKFRFVEFARRRKV"
     gene            19644..20090
                     /gene="msrB"
                     /locus_tag="ACG8LA_001911"
     CDS             19644..20090
                     /gene="msrB"
                     /locus_tag="ACG8LA_001911"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033743 - peptide-methionine (R)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HFQ0204206.1"
                     /translation="MDKPIRPEKEELKEKLSPMAYAVTQENATERPFSGKYDDFYEKG
                     IYVDIVSGEPLFSSAEKYDAGCGWPSFSKPITKRQVREKADFSHGMHRIEVRSKEADS
                     HLGHVFTDGPVDQGGLRYCINSASLKFIPYEKMDELGYGEFKSLVE"
     gene            20260..20862
                     /gene="ruvA"
                     /locus_tag="ACG8LA_001912"
     CDS             20260..20862
                     /gene="ruvA"
                     /locus_tag="ACG8LA_001912"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009379 - Holliday junction helicase
                     complex [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0009378 - four-way junction helicase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HFQ0204207.1"
                     /translation="MYEYLTGVVTFINPYYIVVETNGIGYQIALGNPYRYSSKLNQKI
                     KIYVHQVIREDAHLLYGFDSLEEKQLFLRLVSVSGIGPKSALAIMASEDHSGLIQAVE
                     SSDVTYLTKFPGVGKKTAQQMILDLKGKFGELSIDTPFSLFDEANTKDATALSEAMEA
                     LSALGYSDREIKRVEKQLKEVDNQTTDEYLRQALKLMMKK"
     gene            20875..21876
                     /gene="ruvB"
                     /locus_tag="ACG8LA_001913"
     CDS             20875..21876
                     /gene="ruvB"
                     /locus_tag="ACG8LA_001913"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0009378 - four-way junction helicase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HFQ0204208.1"
                     /translation="MTDEYLLSPESGENELSLEKSLRPQLLSQYIGQRKVKQELQIYI
                     EAARNREEPLDHVLLYGPPGLGKTTMAMVIANEMTVNIRTTSGPAIERPGDLVAILNE
                     LEAGDVLFIDEIHRLPRVVEEMLYSAMEDFYVDIMVGQGPTAHPVHFPLPPFTLIGAT
                     TRAGMLSAPLRDRFGIISHMEYYDEQDLQEIVLRSSDIFQTEIIEEGALEIARRSRGT
                     PRIANRLLKRVRDFAQVQGDGKIDRPIADQALTLLQVDQAGLDYVDQKLLRTMIELYG
                     GGPVGLSTLSVNIGEERETVEDMYEPYLIQKGFLKRTPRGRIATAYAYEHFGYDYHI"
     gene            21905..22483
                     /locus_tag="ACG8LA_001914"
     CDS             21905..22483
                     /locus_tag="ACG8LA_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFQ0204209.1"
                     /translation="MSDTTRTKQLIKNVLIDLCQTQSFRKISVQKIANEAKINRQTFY
                     YHFTDKYDLLRWVYCEDALHYLDPQCLSLDNWEEQALKMLKAIAEKKEFYANTVLSDP
                     EILQKEFSQLIQKSFIKIFEQMDEERQLSARDKLFYARFFSYGCSGVLVNWITNEYEE
                     TPMEIAMQLFRLAKDTELYSYRLYAKEELEEQ"
     gene            22535..23017
                     /locus_tag="ACG8LA_001915"
     CDS             22535..23017
                     /locus_tag="ACG8LA_001915"
                     /EC_number="3.1.3.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight
                     protein-tyrosine-phosphatase"
                     /protein_id="HFQ0204210.1"
                     /translation="MTKILFVCLGNICRSPMAEGLLRKRIALEGREAEFFVDSAATST
                     YEVGKTPHPGTKKILNQEKVDMTNMVARQITPHDFETFDWIIGMDQENVEELKRRAPR
                     SAQGKIHLFLSSIPGKEKENVPDPYYTNNFDETYHLITEGLNHWWNIWIDENKITNNL
                     "
     gene            23134..23508
                     /locus_tag="ACG8LA_001916"
     CDS             23134..23508
                     /locus_tag="ACG8LA_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204211.1"
                     /translation="MNEETVSPMKKLTKLVTHTSYQLFDSFVNDTEEHAKNVRLQGKF
                     ILELQKAATEHSLVILQVRANRLSSKYETISGWVATKTVEKDRVMIRLQNEEQQIRMV
                     PVEQIEKITILSPAGEQERLSK"
     gene            23938..>24434
                     /locus_tag="ACG8LA_001917"
     CDS             23938..>24434
                     /locus_tag="ACG8LA_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISEf1 family transposase"
                     /protein_id="HFQ0204212.1"
                     /translation="MNDFTTEIVQTLVTKGDLNELFRSHLEKAINTLLRTELTAFLDY
                     EKYDRTGFNSGNSRNGSYFRSIKTEYGELTLEIPRDRNGEFKQQTLPAYKRTNDTLET
                     TIIHLFEKGVTMSEIADLIEKMYGHHYTPQTMSNMTKVLTEEVNAFKSRALNDKYVAI
                     FMDAT"
BASE COUNT         8009 a         4392 c         5215 g         6818 t
ORIGIN      
        1 aaaaaaactt ggtacgcaat cgctgtacca agttttttta tttagctttt gattaagcca
       61 taaataataa tttatataag aatactgcta cgacaccagc acagataggt gctacaactg
      121 gtacccatgc atatccccat tgagaagaac ctttatgttt caatggaaga agtgcgtgta
      181 caagacgtgg agcaaagtcg cgggctgggt ttagtccagg acctgtagga ccaccaagtg
      241 aagcaactaa tgtccataca aggaaaccaa gtgctaagtg agctgtacca agattatctt
      301 ggaagaatgg tgcttttgta atacctaggg caccaaagaa taaaacgaat gaaccaaaga
      361 attcattgac gaaaccattg aatttagaac caacgctgtt gattgttgag aatgtaccta
      421 acacatggtt tacgtcttct gtttggtcgt agtaaggttt gtaacaagct actacgatca
      481 attgtccaat cgctgcacca atcaattgtg caatgatata aggaacaact tcagcccaag
      541 ggaatagacc attagatgct aaagcaattg taaatgctgg gttgatgtgg ttaccgctga
      601 ttccaccaaa aatcattgct ggcatcataa ccccgaatcc atacccgaca gcaatcagca
      661 tccagtcact gccatatcct tttgtacctt ttaaatctac gtttgctaca gcaccgttac
      721 ctagaacgat tagtaatgct gtaccaatca tttccgccgc aagacgggtc attagtgagt
      781 aatccataaa tacctccaaa agttataaaa atgcaaaaaa aaaagaaaca tcaacacgaa
      841 aagcatcggt gcagtgtttc gtgtcggaag gatttctgca gtcttaacaa atgtgaataa
      901 aaaaatgaat tccattactt ataagaaacc agaccaacag taaaactcca actcttttta
      961 aaagttctcc acaaatcacc aagcttaact ataaatatac caaaaaaaaa acgttttttt
     1021 tctcaaaaat tgtatcttag aaacagcatg ttttgaaact ttcagaaaag gtttgttagt
     1081 aaaatgaaag ctatacgtaa ggagtgttgt ttgatgaaat tttttcaaga gtttttcatt
     1141 attattttct tttctgtatt aggagaaggc atacggattt ttgctcattt acctattcct
     1201 ggaagtatct taggtattct ttttttattt ttagcatttg aaatgcatct tgttgatcct
     1261 gaaaaaatcg gagcaactgg tgatttttta ttgaataatc tagccatttt atttgttcct
     1321 gctggtgtag gtttattgga atattttgat gatattgctt cgatatggcc tgttttactg
     1381 ggagcagtcg tcgtgtgttc catcgtcacg atggttgcag cgggaaaaac ggcagaaggt
     1441 gtagaagctt tgctgggcta tgtccgtaag aaaaaagcag aaagggtatc tgtaaacgaa
     1501 atggaggaga atcaaattga ctgagttttt tgtgaatcca ttatttggct taagtttgac
     1561 tttaggagtg tacgtattat ctgacaaatt tttgcggaaa tataaactgc ctgttttgaa
     1621 tcctctcgta ttatcgattg ttgttattat cttatttttg catttttctg ggatcagcta
     1681 taaagactat aatatcgggg gcaatttttt gactatgctg attactcctg cgacagtggc
     1741 acttgccatc cctctttata aaaacttccg tttactgaaa gagaattttt atcctgtaat
     1801 ggctgcgatt ttagcaggaa tagtcgcaaa ttgcttggtt agtgtagggt tcggttactt
     1861 cttctctctt cataaagaga tggtgatctc attactacct aaatctgtaa cgacggctat
     1921 ttctgtcgat ttatctcata cgatgggcgg ggtgaatgcc gtgacacttg ctattgttgt
     1981 ctctacaggt atttttggtt cgctgatcgc cactcatatt ttccgcctat tcaagatcga
     2041 aagtccagtt gctcgcggtg tggcgttagg aagtacttct catgctattg gtacagcaaa
     2101 agcaatcgag attggtgaaa tagaaggaat catttccgga cttgcgatat gcgtcaacgg
     2161 aatattgacc gttttattgc taccgttatt ctttcagcct tttgctggct tgttttgatg
     2221 cgaaaaccac tattttatgc tacaataacc aaaacgttcg agcataaaaa aggagggaaa
     2281 gacgtgtatt tgtcttccga gtatcttaaa caatttgata aagatctata ttataagatt
     2341 ctcctcctag aaagttttga ggatcaagct tggcataccg ctgcacaatt agcgcaagtt
     2401 gttcagctgg atgcccgcag cgtgtcgaaa tacctgaacg agctgtctaa aaactatcag
     2461 cagtttagcg gtaagacaca ccctttgttt acaaaaaatc accgttctgg ttataacttt
     2521 tatgatacgc tcgattcaat tgaacatgag cgttttttga tctatctcgt gcaaagtacg
     2581 ctgaaattcc agttgctgca cgacattttt tttgaagaat tccatacaat gtaccaattt
     2641 gcgcaaaagc attacattag tgaatctact gctcatcgaa aaatcaatga atggaaacag
     2701 caactgcaaa cttacggaat tcggctgcaa cgaggtacat atatcgctca aggcgaagaa
     2761 gaaatcattc gactttactt gcatatgaca ttctggcagt tgtttcgagg gaaaatctgg
     2821 ccatttgaaa cgatttctca aatggacgta aagaatatgg cagaacatat catggctttt
     2881 tttaatgttc gtctgaacga gatcaaaaaa agacgattgg aatatatgct aggtgccttt
     2941 tttttaagaa aatcacagaa gcattatgtt gtattgaatg agaaaaaaag acggctgatt
     3001 tctgacaatc tgttgttcca gcgattttgc caggtcatgg agccggtatt tcctaattat
     3061 tttcaagtag aagacgagtt aggcgcatta tttcttgtac tgatgactcg tgaagaatat
     3121 tatagtgatc ctaagatacg gaagaaaatt tttgattttc atcaacaagc aaaaacaccg
     3181 ccctttacag ccctttcaga agcaaaagcc gctctttctc tttatcagga agagcagggg
     3241 ctgccagcag aaaatctaac cttcgaggca gaaaactatt tattcagcag tcattttttc
     3301 gcctatcttt ttcctaatgc gaaagaaacg attgatggca atagtagtga ttttattaat
     3361 catttagtta ttgaaaacaa ggaattgaaa caatggctcg tacatttttt tgaaagtaga
     3421 cacaaacatc ccaatcatct ggcatttaaa aatcatgcgt ttttgatggg gcggtatctg
     3481 actgtgttta aaacattagg agcctttact ccacagcttc caaagatcac gatcctttta
     3541 atgacagatt tcccattatt tgaagagcaa ctgttagagg agggattacg gacatttttc
     3601 cgtaatgagt atcagctgat ttttctgcca acagattatc gggggagaga agttgatctt
     3661 ctgatttcga caagtaaagt ccaccgcaaa ccatgggcgg atcttgacta ttttattgtg
     3721 actgaagaac taaaattaat tgattacatc caactatctc aaaaatttga aatgattcaa
     3781 aaacaaaaac tattaaaaca ataacaaaga aggagaaaaa agatgacatt tgaagaaatt
     3841 ttaccagaat tgaaaaaagg tgcaaagatt attcgtaaag gatggagtgg atttgaactt
     3901 tatgttgttc tcgtatccga tgatgaattt gatggctgtc cggtgacgcc gtacttattg
     3961 atcaaaacaa gtgacgaagg tttttccagc ttcgctccta cagtttgtga tattttagca
     4021 gatgattggg cgatcgtaga atgaaaaacc agtatccaga tctagctaaa caggttgtat
     4081 ttatcacagg agctgcttct ggaattggtg ctgcgcaagc ccgagcgttt cttgaacaag
     4141 atgcttttgt atttggatta gatcaaaagt tcggtaaaat ggaagaaatt tctttgcgat
     4201 ttcctgaaac ttttgcctac gcactaggtg atgttcgaca aatgaaagaa ctccaacaag
     4261 cggtatcgaa atgccaaaat cattttggtg aagttacgat tttactgaat acagcgggga
     4321 tattggatgc ctacaaaccc ttgatggaaa ctgacgaatc gctgtgggat ctgatttatg
     4381 agacgaatgt gaaaagcatg tatcagctga caaaaatcat ccttcctgat atgatccgcc
     4441 aaaaaagcgg aacgatcatc aatatggctt cgattgctgg cttgattgct ggtggaggtg
     4501 ggatcgctta tacaagcgcg aaacatgcga ttgtcggatt taccaaacaa ctcgctctgg
     4561 attacgcagg acagggtatc cgagtaaaag gaattgctcc aggagccatc caaacaccaa
     4621 tgaatgcggc tgattttgaa gggaaaggtg agatggcaga gtgggtggca aatgaaacac
     4681 cagtcaagcg atgggcacag ccggaagaag tagctgagct gacgttattt cttgcctctc
     4741 ctcaagcaag ctacatacaa ggaacgatca tcccaatcga cggcggatgg ttgttaaaat
     4801 aaccttgtgt ttttttcaag cttctgtatg ataaaactaa agagagaaac aacggttgat
     4861 gataaaaaaa gtcgatgact gttcccgaca ttcgatgccg aacagccagt tcaaaaaatt
     4921 ctttttaata atcgttaata ttcgaaacta agcggctttt cacgacctct tgatataaac
     4981 gatattcaaa agcttgcaac tgcggtaaca agtccagcca aatgaaaaat ataaggagct
     5041 atttttattt gaccattctt attacttgtt gcagggcagc tttttcacta ccttctgcga
     5101 cacttcagtt ggaattttct tcccatcctt tggtcgcggt cattaccaag ataaaattat
     5161 cttgcaaagg agaaatagaa catggaaaaa aataataccc gttcagccaa acgctggaca
     5221 acgacagatg tgactcggat ggcgctagtc actggtttat atgtggcagt gacgctggtt
     5281 ttgtctgtct ttagctttgg agtgattcag attcgtctct cggagatgtt caactatctg
     5341 tccttgtata acaaaagata catcgtcgcg gtaacagcgg gagtagcttt ggctaatatt
     5401 gcttctcctc ttggactgat agatgttgca gtaggaagcg tcagcacgct gcttgtattg
     5461 cttatcaact ataaaatcac tagtcgcatc aaaaacatga aaatcaaaat ggccgtgaca
     5521 gcatgcgtat ttgctttttc catgtttaca gtagctggtc agctaacgat tttatatcaa
     5581 ctaccttttt tcttgaattg gtgggtgatt gctttaggag aattggcatc aatgattgtc
     5641 ggtgggataa ttatttattg gatcggtaaa aaagtggatt tgtcaaaata aagatctgtt
     5701 taatttaaaa tagggcagca tggaagagac tgaatgttga gtcttcttcc atgctgcttt
     5761 tttgattaat ttgtatgaag aaatcgattt agccgttttt tcatcaagat accgatataa
     5821 gctgctccag ttgccttgat tgcttccggc agtaaaaacg gcagtagtcc actggcaaat
     5881 gcagttgtaa aagtaagatc accacttatt ttcagccaga tcgttccgca gatcaatgca
     5941 gcaagagagc ccattagatt ggcaaagatt gcatataagt aatgagcatc cgttctttcg
     6001 atcatccaac cagttatcca cgtttgtaag agaaatccaa tcaaatatcc gccagttggc
     6061 ccaaataaaa cagctatacc tccagtcatc cctgaaaata caggaagacc aatcaagcca
     6121 agtaaaagat aaactccaac agatatcaat cctagttttc ttccgagaaa agttgctgtt
     6181 aatccaatag caaatgtttg ccctgtcaaa ggaaccaaac caaaaggaat ggtcatctga
     6241 gaaaggacag aaataatcgc ggcaaattcc gcagcaagta tcaattcttt caatgttcgg
     6301 ttcataacgc cctcttttcg ttaacttaat atttttattt ggttaacgaa attgtaaaac
     6361 aaagtgatta ctttgtaaat agaaaatata aaaaaagacc agctatccaa tagatagcgg
     6421 tctttttcaa gaaagctttt gaaattataa gctttggttg tagtattcaa cgacaagagc
     6481 ttcgtcgatt tctggatata gttcgtcacg ttctggtaaa cgagtcaatg aaccttccaa
     6541 tttttcagcg tcaaagctta cgaatgctgg gcgtccaaca gttgcttcta cagcttcttt
     6601 tactgttacg atgttttgtg atttttcacg aactgagatc acttgaccca cttctacgtg
     6661 gtatgaaggg atatcaacgc gtttgccatc aactaaaatg tgaccatggt taactaattg
     6721 acgtgcttga cgacgagtcg ttgcaagtcc taaacggtaa acaacattgt ctaaacgttg
     6781 ttctagtaag atcatgaagt taacaccatg tttaccttct ttgattttgc tagcttttac
     6841 gaacaagtta cggaattgac gttcgttcat tccgtacatg tgacgaagtt tttgtttttc
     6901 agttaattgc atgccgtatt ctgattgttt gccacggcta ttaggtccat gttgacctgg
     6961 tgcgtaaggg cgacgtgcta attcttttcc tgtgcctgac aatgagatgc ctaagcgacg
     7021 agaaattttc catgatggtc ctgtataacg agacattaaa atttcctcca atgaatataa
     7081 gtttttggag taaaataatc cgttgaaaaa ttcataatca tatagtttgt tcttcaatct
     7141 tcacctttgc agccgcggtt acacaatcga acccgagacg gggcaacaaa ctagggatga
     7201 gttattattt ttctgctgca ttattttaca caaattacag tatatgatag atcatccacg
     7261 aatgtcaaga taattagtac ataaaaacgc tttacaaacc taggctgtct ttataaaatg
     7321 agagggtatg tgcaaatgga aaaaagcgaa ggaagtttaa ggagaaaatc aatgaatccg
     7381 gtatcaccat tatttgagaa aatcgatgct tcaattgaaa agaaggcgaa tctttttgaa
     7441 aacagctttt cacgttacgc tgttcgagcg gttctcgcct gtttgttttt gactttagga
     7501 acggctgtgg catttgcgat cgcgatgaag ggggaagata tcgcgcatgg tctaggaaag
     7561 attttatacg catttatgtt cagctggggt ctggtcatga ttctatacat gaacgccgaa
     7621 ttaggaacat cgaatatgct ttatatgacc gtgggtgttt ttcggcagag acttgcttta
     7681 agtaaggcag ccaagattct atttgcctgt atttttttca atatgattgg cggtatatta
     7741 tgtggatttc taatttctat gactacgcca tttcaagatt taacgttgga caactttatg
     7801 ttagaatcaa tagcagtaaa actagcaaaa ccttcagcaa cgattttggt ggaagggatg
     7861 tttgcgaata tcgttgtcaa taccgctgta ctgatcagca tgcggatgaa agaggatgtc
     7921 ggaaaagtga tcacagtcgt attcatcatt ttcatttttg cttttttagg atatgaacac
     7981 gtgatagcga attttcctgc ctttacgctt acttactttg cttctcacgg acagatggat
     8041 ggaatgacag tcagcaatgt gttacataat ttgttttttg ctttggcagg aaattatatt
     8101 ggtggcggtt tagtaatggg actgggatat gcttggctga atcagtcaaa atcatcctat
     8161 gtggactaaa aagtcgttca ttaaagggga agtgccatgg aagttttagt ttttccaaaa
     8221 aatgaggaaa aagcgttaca aatggaaaag tacatgaaaa atcttttttc ctttgctgga
     8281 gtacctaagc cggaacgcgc tcttttacaa caaccgttac tggatgagag caaaaattta
     8341 tctatttctg aagttttagc ttttgttcat tattattatg aacaaatcga aagagagtat
     8401 cagtatgtag cgatcgattt agtccagaaa aacatcaaac ggcttacatt tgaagactta
     8461 gtcgtattgt tgccactagt tcagaaaaaa gaatggtggg acagcatcga ctcttggaga
     8521 aaagtataca gcacatggtg taaagcctac ccagagcagc gtgaagaagt ctttcaattg
     8581 tttgaaaaaa aggaagattt ttggctacgt cgaatagcaa tcacgttgca attaggttat
     8641 aaacagcaaa cagacacagg actattgatc cgagcaatag acgaagatcg tcaaacaaag
     8701 gaattcttta tccaaaaagc aattggttgg gcattacgcg attatagtaa gaccgatgcc
     8761 gattgggtaa aaagacagct gacaacagat ttgagtaagt tagctgttcg agaggcaagt
     8821 aagtatttat aagaaagcga gacgacaaga gatgagacgc aaattatttg cttttgatat
     8881 tgatggaacg ttgttagatt caaacaaaca agctttagat agcacaagag aagcattgga
     8941 aaaattacgc aaagccggtc atctggtcac gattgctaca gggcggagcc gatttcatgc
     9001 gcaagagatc attcgcgatc ttgattttac gaactacatt ttatgtaatg gagcggccgg
     9061 ttttttagac catgaacaag tatataagaa tttactagat cgcgaccagt tggatgcgtt
     9121 cgttcaagaa gcgcatcatg agcagatcga tacagctttt gtcagcttag acaatatcaa
     9181 gcgttcttct tccaatgatg taacggtgat ggaagaagcg atgcattctt tcggtgctgt
     9241 cttgcctgaa ttagatcagt tttttgcaga ggaacaagaa atataccaag cgttagcatt
     9301 tttcgatcaa acatatgatg ggaagttctc ttcatatgat aaaattcgat ttgtccgctg
     9361 gcatgagaac agtgtagatg tcgtacctaa aaatggttct aaagcagcga caattctgca
     9421 cttagcagaa caagtaggca tccctcatga agacatcatc agctttggcg atggacaaaa
     9481 cgaccgtgaa atgttgcgca tgtcaggaat tgggatagct atggggaatg ctgtgccaga
     9541 agtacaagca gaagctaaga tggtcactga tacaaacgat caggatggaa tttggaaggc
     9601 attgaaagag ttaagcgtga tttaaaagag gttgtgaaaa agctgttctg catcaagtaa
     9661 taagcccagc caaacaaaaa tagctcctcc tatttttcgt ttttctgggc ttattaccgc
     9721 agatgcaagc tttcgaacac cgtttaagga agaggtcgtg acagaagtgg tcagtttcaa
     9781 gaaataagaa gggatttacg aaaattgctt ctcaaatttt tgtaaaatta cggcttattt
     9841 ctgaagaagt agatgaaaca acgtttattc gggaaatggg actgtgacaa gatgtttgtc
     9901 atagtcccat ttttttattt tatttttcaa aactaagaaa taccaggaaa gagttccttt
     9961 tgtttgacct tttctttctt attgaaaaca actataatat agagtgatgt taaaagagaa
    10021 gaggaattta gtgtgcgggt attgtttatt ggtgatgtag taggttcaat gggacgagag
    10081 atgattactg aatatcttcc tagattgaag aagaagtacc gtccgcaagt aacgattgta
    10141 aatggtgaga atgccgcttc tggacgtgga atcacagaaa aaatctataa aaaatttttg
    10201 caagacggcg tagatgtcgt gacgatgggg aatcatacgt gggacaaccg cggaatcttt
    10261 gagtttgtaa atgaagctaa aaagatggtt cgtccggcaa attttccgga agggacgcct
    10321 ggacaaggga tggtctttgt caaagtgaac caagtcgaac tggcagtgat caacatgcag
    10381 gctcgttctt ttatggtgga cttggatgat ccttttcgta aaatgaatga gctggtagaa
    10441 gaagccagaa aacgtacgcc gatcattttt gtagattttc atggagaaac aacaagtgaa
    10501 aaacaagcaa tgggctggtt tttagatggg aaagtttcag cagtggtcgg tacacataca
    10561 cacgttcaga caaatgatgc gcgaattttg ccaagaggaa cagcgtatct gacagacgtt
    10621 gggatgacag gtccctatga tggtattttg ggtatgcgca gagaacctgt aatcgaaaag
    10681 tttctgactg cattaccaaa acgttttgaa gttgtggaac aaggccgatc gattttaagc
    10741 ggctgtatct tggaattgga tgatacgaca ggtcatgcaa aagaaatcca gctgattcag
    10801 atcaacgatg atcgaccgtt catggagtag aaagagaggc agttttttgc agcaggagcc
    10861 ggaaattcaa aaagaagtaa ggaaactgac aaaactttta agagagaatg aaacgatcat
    10921 tcgctacaaa gaacttgaag aaaagatcca gcaaaaccag tatttagctg agttgagaga
    10981 aaaaatcaaa caagcgcaaa aagatgctgt tcattttgcc cactatgaca aaccagcagc
    11041 agaaaaagaa gcaatcaaac aagcggatca attcatgcaa gaatttgatc agcatccgct
    11101 tgttgtagct tatagaaaac agctgttgga agcagatgat ctgcttcatc atttaacaac
    11161 tatgatacaa gaagaaatca atggacaaat agaggaggaa aaacatgcct caaaaaacta
    11221 aaaatactcc tatgatggaa caatatctaa gcatcaaggc ccaataccaa gatgcttttt
    11281 tgttctatcg tttaggagac ttttatgaac tattttacga agatgcgatc aaagcgtcac
    11341 agcttttgga attaacgttg acgagcagaa atcgaaatgc agaagaacct attcctatgt
    11401 gcggtgtacc tcaccatgca gcacaaggat atatcgatgc cttgattgaa aaaggctata
    11461 aagtagcgat ttgcgagcag gtagaagatc caaagacgac taaagggatg gtcaagcgcg
    11521 aagtgatcca gctagtcact cctggtacag tcatggacag caaaggattg tcggcaaaag
    11581 acaacaattt tttaacagct gtagttagtc aaggaaatga atttggcttt gcttatgccg
    11641 atttaagtac gggagaattg aagacggctc ggttgcatga tgaagaagct gttttaaatg
    11701 aagcctctgc attgcagaca aaagaactcg tattaggcag tgagatcact gatacccttc
    11761 gtgaacagct aagcgggcgt ttagggctag tcttttctca acaaaatgag atggaagaaa
    11821 acgcggaatt tagctttttg acaagcgaac tagtcgatcc gctggaaaaa gaagcaaccg
    11881 gcaaactatt gacttattta tcggtgacac aaaagcggag tttagctcat atccaaaaag
    11941 cagtagaata ccaaccagat cattttttga aaatggatta ttattcaaaa ttcaacctag
    12001 aattaagcca atctattcgg actgggaaaa agcacggcac tcttctatgg ttgttagatg
    12061 aaacaaaaac agcaatgggt ggccgtttac taaaacaatg gctagaccgt ccgcttatcc
    12121 aggcaaaaca aattaaagca agacaagaaa tggtcgcttc tttgctagac agctattttg
    12181 aacgtatcga tttgcagtca gcattaacga aagtctatga tctggaacgc ctagcaggtc
    12241 gagtagcttt cggtaatgtc aatgggcgag acttgatcca gctgaaaact tctttagaac
    12301 aagtgccaat gatcagaggg ttgattgaag gaatcgatca aggtcaatgg caaagtctgc
    12361 tttcagaaat gcagccgatg gaccatctcg tccaattgat cgaccaagct atccaagatg
    12421 atccgccgtt acaaataacg gaaggaaaca tcatcaaaga tggattcaat gagcagctcg
    12481 atatgtaccg ttctgctatg agaaacggaa agaaatggtt ggcagaactt gaagcaaaag
    12541 agcgtcaaga aacaggaatc aagaacttaa aaatcggatt taaccgcgtt ttcggttatt
    12601 atatagaaat tacaaaagca aatcttggaa atgcagaact ggagaagtat gaacgaaaac
    12661 aaactttagc aaatgcagag cgtttcatca caccagaact aaaagaattg gagacacaaa
    12721 tcctcgaagc agaagaaaaa tctgttgatt tagaatatca gttgttttta gctgtgagag
    12781 aagaagtcaa aaaggctatc cagccgctac aagtacttgc aaaagcaatc agtgcagtag
    12841 atgtgctaca aagttttgca acgatcagcg aacgctatca gtatgttcgg ccagaacttg
    12901 tcagtgacaa gcatcagctt ctgatcaaag acggacgaca tcctgtagta gaaaaagtat
    12961 taggacatca ggaatatatc cctaacagcg tagaaatggc agaagacgaa atgatcttgc
    13021 tgattacagg accgaatatg tctggtaaaa gtacgtatat gcgacagttg gcattaactg
    13081 ttctgatggc gcaaatgggc tgtttcgttc cggcaaaaca agcagtttta cctatttttg
    13141 atcggatttt tacccgaatt ggtgcaagtg acgacttaat tgctggacaa agtactttta
    13201 tggtagagat gatggaagcc aatcaagccc tgcgttatgc tacgccaaac agtttgattt
    13261 tgtttgacga actagggcga ggaacagcaa cctatgacgg aatggcgttg gcccaagcaa
    13321 tcatcgaata tatccatcgt catgtacaag caaaaacact cttttctact cattatcatg
    13381 aactgacggt acttgagaaa gaacttccgc agcttaaaaa tgtccatgtt ggagccgttg
    13441 aaaaagacgg agaagttgtc ttcttgcata aaatgatgga tggacctgcg gataaaagct
    13501 acggcataca tgtggcaaag atcgcaggat tgccttccaa tctactagaa cgagcagcag
    13561 atatcctgca tacgctagaa aatggcgata acggacacca tactgttcca gctgaagtag
    13621 aagagaaaac taaaacagcc aaacaggagc aaataaaacc acctgcagaa aaagtaaatc
    13681 aagaccatat acaagaccgt gtaaaagaag aaaaccaaca gctttcttta ttcagtgaat
    13741 tatccgaaaa tgaaacagaa gtcattgaat cactgaagca aataaattta ctagaaatga
    13801 cgccaatgga tgcactaaac acattatatg aattacaaaa acaactgtag gaagaaggcg
    13861 gatatcgatg gccaaaatcc aagaattatc tgaacgttta gctaatcaga tcgctgcggg
    13921 agaagtagtg gagcgaccag cttccgttgt gaaagaatta gtggaaaatg caattgacgc
    13981 cggcagtact cagattgata tcttagttga agaagcggga ctgcggacga tccaagtgat
    14041 tgataacgga gaaggcattt tggcagacga cgtagagaat gccttcaagc ggcatgcgac
    14101 aagtaagatc cataatcgcg acgatctttt tcgcatacga acgctgggct ttcgagggga
    14161 agctttgcca agtattgcct ctgtttctga aatgactctg gaaacggcga atcaggaaga
    14221 aaaacaaggc acctatctgt cgctgaaagg cggagaagtt attgagcatc gaccagcacc
    14281 actgcgtcaa ggaacgaaga ttaccgtcag caatctgttt ttcaatacgc cagcccgctt
    14341 gaaatacgtg aaaacactgc acacagaatt agcgaacatc ggggacatcg tcaatcgact
    14401 ggcattgagt catccatcga ttgcttttcg tttagtacat gatggaaaca aaatgctggc
    14461 aactgctgga aatggcgatc tgaaacaaac aattgcggga atctacggat tatctaccgc
    14521 aaaaaaaatg ctgaaaatcg aaggaaaaga tctagatttt gagttatttg gctatgtttc
    14581 attgcctgag gtgactcgtg ccagtaggaa ttacttatcg acgatcatca atggacgttt
    14641 tatcaagaac ttttccttga ataaagcaat cgttgcaggt tatgggtcaa aattaatggt
    14701 cggtcgtttc cctattgctg tattggaaat caaaatggac ccgcttttag tagatgtaaa
    14761 tgttcatccg acgaagcagg aagtccggct gtcgaaggaa aaagaactaa cagagctaat
    14821 tagtaacgcc attcaaaaag cattgtctca agaaaatctg attccaagtg cagcggataa
    14881 tctacggttt aagaaaaaag tacctgatca gcctaaaaca gaacaaatcg aaatcgattt
    14941 gtcctacgct tttgaagaag aaaaacctaa aaagccaagt agtttgaatt ttgatcgaca
    15001 gacaggtacc tttttcgtag aagaactaaa gaacacattt gttgacagaa ttgttgataa
    15061 gtctgtggaa aatgttgaaa actattctgg tttttctgaa gaaaacacca cttatccaga
    15121 aaaaacagcg aaaacggtgg ataagtttgg tgaaaatgtt gataactttg tagaaaaaac
    15181 agtggaaaaa tctgaaaaga aagaatttcc cattgtggat aacatggaga aaacaaatga
    15241 agaacaagca gataaatccg tagaagagga tgaaaagatt tacgaggaag aattgacact
    15301 ccatcctgaa tttgatttca ctcaaggaaa cgacaaaaca ttagaacaag ccatcaagaa
    15361 attagaaacg gaaaaaccag tacaacgttt tcctcagttg gaatattttg gacagatgca
    15421 cggaacgtat ctttttgccc aaagtagcga tgggttgtac atcattgatc agcatgctgc
    15481 ccaagagcgc attaagtatg aatatttccg ggaaaaaatt ggggaagtat ctgatgatct
    15541 gcaagaattg cttgttccat ttgtgttaga ctatccaaac agtgatgctt tgaaattaaa
    15601 agagcaaaaa cacttgctag aagatgcagg gatttattta gaagaatttg gtcaaaacag
    15661 ctttattgta cgggcccatc ctacttggta tcccaatgga gaagaagaat cgattattcg
    15721 ggagatgatc gatatgctgc tgacaactgg aagtgtgagt gtaaaaaaat tccgtgaagc
    15781 aacagcaatc atgatgagtt gcaaacgatc gattaaagcc aaccattatt tgaatgaagc
    15841 acaagcacgt gtgctgctga aggatctggc acgatgcgaa aatcctttca attgtcccca
    15901 tggccgtcca gtattgattc actttaccaa ttcggatatg gaaaggatgt tcaaacgaat
    15961 ccaagacccg cattaagtca aagagaagag ggaaaacatg aagattgtat tagcatccca
    16021 atcaccaaga agaaaagagt tattggctca tatcgtttca gaattcgaga ttgaacctgc
    16081 tgatatcgat gaaacgccat ttccagacga acagcccgtc gattatgttc gtagaatggc
    16141 tgaagaaaaa gcacgaactg tctgggaaca agatgaaaaa gaagaccatt tagtgattgc
    16201 cagtgacacg actgttgttc tcaatcaaga gatcatgggt aaaccagaag atctggctga
    16261 ggctgaattc atgctgaaaa aactaagcgg ggaaacacat actgtatata cagctgttgt
    16321 tttaaaaaca aaggaacgag aagaacggat actagcagaa gcacatgtca ctttttatcc
    16381 tttgacagac gaagagatca aacgctactt ggagacgggg gattatgcgg ataaggcagg
    16441 ggcatacggc atccaaaatg ctgcgagtgt attcgtcaaa gaaatttctg gagattatta
    16501 cagtatcgta ggatttccga ttggtgctgt caatcaggca ctgaaaacat tcatttaaac
    16561 aaaaaagcgg actatctgat tttcgattga aaatccatga tagcccgttt tttttattga
    16621 aaagattact tatctactct gactaagatt ttacttcagc tttaccgact gcttcgcccg
    16681 ggcgaacaag tcctgattgg tcaagagaaa gtcctgcaac tttttcatta ttggtcaaag
    16741 caacaataat gtcagttttc ttgccagctt gttctatttc tggcaaatcc atttcagcaa
    16801 tcagggtctc tggtgtgaca aggtatcctt ctttcacgaa tacattgaaa ggaacaccct
    16861 ttagttcaac agtatctaat cccatgtgaa caagtacttc cagcccctca ttagaaagaa
    16921 taccaatggc atgttttgtt tcaaagacac tcgtcacttt accgtttact ggtgcataga
    16981 ctttgccgtt tgacggttcg acagcataac cgtcacccat cattttttgt gagaaaactg
    17041 ggtcatttac ttcagttatt tccttgatgg tccctgcagc gactgcgaat aatgtttctt
    17101 ttgttgcaac tgccgtacca gttgctgaaa caggttcgaa agactgtggc gttgctgttg
    17161 cgccatttgc tgtttgaagt tgtacatcag cagcattttc aggaacagca ggatcaatct
    17221 tattcaaaat tccctgacgt ctaaagatga tcgtcaagcc aaatggaatg atgacagcaa
    17281 tgatcattgc gatgatgaaa ggtacccatg tttctgcttg gatagctagt attcctggca
    17341 aaccgcctac tccgatcgcg ttagctcgaa cacccatcaa gttagcaaac atgccagcta
    17401 atccagagcc gaccattgca gcgacgaaag gatagacgta tttcaaattg attccgaaca
    17461 tagcaggttc agttacgcct aagtaacaag aaatcattgc tggaatcgag atttgttctt
    17521 cttttttatt cccacgatgt aagaagatga tggctaagac tgcagagcct tgggcgatat
    17581 ttgataaagc aatcatcggc cataaattcg ttgatccgaa atctgcaatc agctgcatat
    17641 cgatggcatt ggtcatatgg tggagaccag taatcactaa aggagcatac aggaatccga
    17701 atacggcact aaacaaccag ctgatagaag acgtcaatcc agtatttacg atatttgaga
    17761 tccagcttcc gactgtccag ccgataggac ctaaaataac gtgtgcagct aaaacagttg
    17821 gtaacaatga aaacaatgga acaaaaatca tcgagatcga ctgagggata tatttgcgga
    17881 agaagatttc tagatacgct aacataaacc ctgccagcat ggctggaata acttgcgctt
    17941 gataaccaat catctggact tgagcaaaac caaaatccca aaatggaata tctgctgcgg
    18001 ctgtggaagc tacactataa gcatttaata attgcggaga aactaacgta attcctaaaa
    18061 cgattcctaa tatttgtgta gtacccatct tttttgcaat actccaagtg atacctactg
    18121 gaagaaaatg gaaaattgct tcaccgggta accacaaaaa ggcattgaca ccattccaaa
    18181 acttcgagtg ttcaacgatt gttccaccaa gactttcaaa ctggatacct tcaagtacat
    18241 ttctgaatcc aaggatcaat ccaccgacaa tgattgcagg aatcagtggt gtaaagattt
    18301 ctgctaaaac ggcaatagca cgttgaacgg gatgaaggtt ttgttttgca gctgcttttc
    18361 cttgttcttt ggaaacccct tcaactccag atactgcaac gaagtcgtta taaaaagtag
    18421 aaacatcgtt tcctatgatg acttggaact gtcctgcatt cgtgaacatc ccttttacgc
    18481 taggtatatc ttcgatcgct ttttcgtccg cttttcctgg atcattcagg acaaaacgca
    18541 tacgagtcgc acaatgacta actgcagcaa tattttcttt tccgccgata tcatgtaaca
    18601 gcttctcggc atctgcttga tattttgcca tatcaataaa cccctttctc ttaacttgtc
    18661 tatgcaagtt gtttcttcat ttactatact ttttttcgga gagaattgca agcgttttat
    18721 taaaaagtac gagagaaaat gatatcgttt taaaaagctt aaaataagct tttcttaaaa
    18781 ataggaacat tgaaatacaa aaagagctgt agtatagtga agaaatgatg gaagaacgag
    18841 tgagggaaaa aacatgaata agttcaatga aattttttta gatttggaac agaaaatttt
    18901 agcgaaagaa tatcctccgc attcgctttt acccagtgag aaccaattga tcaaaattta
    18961 tggtgtttca cgagaaacaa ttagaaaagc gctgaatctt ttgactacgg aaggttatat
    19021 tcaaaaaaaa caaggaaaag gttcgatcgt actggatcgg aatcgcttcg actttcctat
    19081 ttctggattg actagctata aagagctaca ggagacccaa cgtattccaa gtgaaacgat
    19141 catccatacg ttagaagaaa cagaagtgac aaaagcattg aacgagatca ctggctggga
    19201 gatcggtgcg cctgtttggc atttgatacg cgaaagaaaa atcaatggcg aagtagttat
    19261 attagacacc gattatctat taaaggaaat cgttcctatt ttaactccag cacaagcaca
    19321 aggatcgatc tatgaatatt ttgaaaatga gctttctttg acgattgctt acgcgcaaaa
    19381 ggagatcaca gtagaagaag taacggaaat catgaaaaca gcgatggatc ttcacgatga
    19441 cacttatgca gtagtagtca gaagcctcgt tcatctggaa gatacccgct gtttcgagta
    19501 ttctgagtcg gttcaccgat tagataaatt ccgtttcgtt gagtttgccc gacgccgaaa
    19561 agtgtaaata gttcaaaaga aagcaaattg ttggcatctg tccactttgg cgctatgata
    19621 ggatcacaaa gggggcattt ttaatggata aaccaataag accagaaaag gaagaactga
    19681 aagaaaagtt atcacccatg gcttatgcag tcacacaaga aaatgcaaca gaacgaccat
    19741 ttagcgggaa atatgatgat ttttacgaaa aggggatcta tgtagatatc gtcagcggtg
    19801 aaccgttatt cagctctgca gaaaaatatg atgcaggttg tggctggcca tcattcagca
    19861 aaccaataac gaaaagacaa gtgcgcgaaa aagccgattt ttctcatggc atgcatcgaa
    19921 tagaagttcg aagcaaagaa gcagattctc atctcggaca tgtgtttacc gatggaccag
    19981 tagatcaagg tggtctacgt tactgcatca attctgcctc actgaaattc attccatatg
    20041 aaaagatgga tgaattaggt tatggggaat tcaaatcact tgtagaataa tggaaataca
    20101 caaagagcgg tacaatacgg ggatttactc gatcgtccgc tcttttttta ttcaagcgat
    20161 tgctatttga aagaaacgct ccctagactc cttttttcac aaggtgaaat gtgctacaat
    20221 aaagggaacg tatgtgtgca aaagaaagag gactagaata tgtatgaata tctgacaggt
    20281 gtggttacct ttatcaaccc ctattacata gtagtagaaa ccaatggtat cggctaccag
    20341 atcgcactag gaaatcctta ccgctacagt agcaaactaa atcaaaaaat aaaaatttat
    20401 gtccatcagg taatacgtga agatgcgcat cttctgtatg gatttgattc gctagaagaa
    20461 aagcaactgt ttttgcgatt agtaagtgtt tcaggaatcg gtccgaaaag tgcccttgca
    20521 atcatggcaa gcgaagacca ctccggtttg attcaagcag tagaatccag tgatgtcact
    20581 tatttgacga aatttccagg agtagggaaa aagacagcac aacaaatgat cttggatcta
    20641 aaaggaaaat tcggtgagct gagtatcgat acacctttta gtctatttga tgaagcaaac
    20701 acaaaagacg ctacagctct atctgaagca atggaagctc tctcggctct tggttacagt
    20761 gatcgagaaa tcaaacgtgt agaaaaacaa ttaaaagaag tagataatca gacaacggat
    20821 gagtatctac gccaagcact caagctaatg atgaaaaaat aaggaggaga ccaaatgaca
    20881 gatgaatact tgttatcacc agaatctggc gaaaatgaac tgagtttgga aaaatctctt
    20941 cgaccacagc tgctttctca atatatcgga cagagaaaag tcaaacaaga acttcagatt
    21001 tacatcgaag ctgccagaaa tcgggaagaa cctttagatc atgttctgtt gtacgggcct
    21061 cctggattag gaaaaacgac gatggccatg gtcattgcta atgagatgac cgtaaatatt
    21121 cgtacgacga gtggccctgc tatcgaacgt ccgggtgact tagtagcaat cttgaatgaa
    21181 ctggaagcag gggatgtcct gtttatcgat gagatccatc gattacctag agtggtagaa
    21241 gagatgcttt attcagctat ggaagatttc tatgtagata tcatggtagg acaagggcca
    21301 accgcacatc cggttcattt ccctcttcct ccctttactt tgattggcgc gacgacacgg
    21361 gcaggtatgc tttctgcacc tttacgagat cgatttggca tcatttctca tatggaatat
    21421 tatgacgaac aggatctgca ggagatcgtt ttacgttctt cggatatttt tcaaacagag
    21481 atcattgaag aaggggcatt ggaaattgct cgccgatcac gaggaacgcc tagaatcgct
    21541 aatcgcttgc tcaaacgggt tcgtgatttt gcgcaagtcc aaggagacgg gaaaatcgat
    21601 cgtcctatag cggatcaggc acttactttg ctacaggtcg atcaggctgg attggattat
    21661 gttgaccaga aattgttgcg aacaatgatc gagttatatg gcggcggacc agtagggtta
    21721 agtacgcttt cagtaaacat aggagaagag cgtgagacgg tagaagatat gtatgaaccg
    21781 tatctgatcc aaaaaggatt tttaaagcgt acacctagag ggcgaattgc tactgcttat
    21841 gcctatgaac attttggtta cgactatcat atatgatttt tgcttttaga ttggaggaaa
    21901 atgaatgagt gatacaacac gtacgaaaca attgatcaaa aacgtattga ttgatttgtg
    21961 ccaaacgcaa tcttttcgaa aaatcagcgt ccaaaaaatc gcaaacgaag caaaaatcaa
    22021 tcgacaaaca ttttattatc attttacaga taaatacgat ttgcttcgtt gggtctattg
    22081 tgaggatgca ttgcattatt tagatccaca atgtctttca cttgataatt gggaagagca
    22141 agcattgaaa atgctgaaag caattgctga gaagaaagaa ttttatgcaa atactgtgct
    22201 ttctgaccca gaaattttac aaaaagagtt ttctcaactg atccaaaaat catttatcaa
    22261 gatttttgaa caaatggatg aagaaagaca actttctgca agagacaaac tattttatgc
    22321 tcgttttttt tcttacggtt gcagtggtgt attagtcaat tggatcacga atgaatatga
    22381 agaaacaccg atggaaatcg ctatgcagct tttccgttta gccaaggata cggaattata
    22441 ttcttatcgt ctttatgcaa aagaagagtt ggaagaacag taatagaaaa attttttgtt
    22501 ggaaaagcaa taatcgctaa aaggagatgg ggaaatgaca aaaattttat ttgtttgttt
    22561 gggaaatatt tgccgttcac cgatggcaga aggcttgctg agaaaacgaa tagcattaga
    22621 aggaagggaa gcagaatttt ttgtggattc tgctgctaca agcacgtatg aagttggaaa
    22681 gacaccgcac cctggaacga aaaaaatatt aaaccaagaa aaagtagata tgacgaatat
    22741 ggttgctcgg caaatcacac cccacgattt tgaaactttt gattggatca ttggcatgga
    22801 tcaagaaaat gtagaagaac tgaaacgaag agcaccacgc tcagcgcagg ggaaaatcca
    22861 tttgttttta agtagcattc ctggaaaaga aaaagaaaat gttcccgacc catactatac
    22921 caataacttt gatgagacat atcacttgat cacagaaggc ctgaatcatt ggtggaatat
    22981 ttggattgat gaaaataaaa taacaaacaa tttgtaaagt taacgctttc tttttaaggc
    23041 gatgttagag catttccttg tttttttgta aaatgttagg taaaataaaa ttaattaagt
    23101 aacactttct tagctaaagg aggagtgcat tcgatgaacg aagagacagt atcgccaatg
    23161 aagaagctta cgaagttagt tactcatact tcgtatcaac tttttgattc ttttgtaaat
    23221 gacactgaag aacatgctaa gaatgtacga ttgcaaggaa agtttattct tgagctgcaa
    23281 aaagctgcta ctgaacatag tctagttatc ttacaagtaa gagcaaatcg tttgagtagc
    23341 aagtatgaaa cgatctcagg ctgggtggcg acaaaaacgg tcgaaaaaga ccgagtgatg
    23401 atccgcctac aaaacgaaga gcagcagatc cggatggttc ctgtagaaca aattgaaaaa
    23461 ataacaatcc tttcaccagc aggggaacag gaacggttat caaaataatt tataccagat
    23521 agaaaagcac gtatgagctt gtaccatcaa tcattactaa tcaaaaataa ccgaatgctt
    23581 taagctgata tcagtaaaac ggaacgtttt aggatgagta tcatagcatg acagcattcg
    23641 gttgattagt tgaatcgatt ggatggtaca agtttttttg ataaaaaaag gtcctgctag
    23701 ccggggagct agcaggataa ggagttaaaa atgaaaaagt gttgttaggg ttgtttgttg
    23761 gtatgcttat ataatagtca ttagttgtga atattttgtg acgaaagttt tcgaaagttg
    23821 ttaagttttt gagagtataa aatattttgt gtaaatgaaa aaatccatac aaaaaaggaa
    23881 gtcccttctg tagaataaag ttaacgacaa ccaattcaca gaaaagagga cttccctatg
    23941 aatgatttta ctacagaaat tgtgcaaact ctagtcacta aaggcgattt aaatgaatta
    24001 ttccgttcgc acttagaaaa agcgataaac acactcctac ggactgaatt aacggctttt
    24061 ttagattacg aaaaatatga tcgcactggt tttaattcag gtaattcgag aaacggttct
    24121 tactttcgat caatcaaaac cgaatatggt gaattaacat tggaaatacc tagagatcgt
    24181 aatggtgagt ttaaacaaca aactttacca gcctacaaaa gaacaaacga tacattggaa
    24241 accactatta tccatttatt cgaaaaaggt gttacgatgt ctgaaattgc tgatttgatc
    24301 gaaaaaatgt acggtcatca ctatactcca caaaccatgt ccaacatgac taaagttctg
    24361 actgaagaag taaatgcctt taaatccaga gccttaaatg ataagtatgt cgctattttt
    24421 atggacgcta ctta
//
LOCUS       DAZKKZ010000046        23733 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.047, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000046 DAZKKZ010000000
VERSION     DAZKKZ010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23733)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23733)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23733
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.047"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(1..120)
                     /locus_tag="ACG8LA_001918"
     CDS             complement(1..120)
                     /locus_tag="ACG8LA_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HFQ0204213.1"
                     /translation="MVFQKPLNNFRYIVYYCHTKIKKNKQKETVTKVLSQSLI"
     gene            299..1960
                     /locus_tag="ACG8LA_001919"
     CDS             299..1960
                     /locus_tag="ACG8LA_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HFQ0204214.1"
                     /translation="MKKKFTFGLVAVCGLVLAGCYGGSSATSSSSAKSGSADGGGVFN
                     LVVPQEMPTADLSVATDTISFTALNNVYEGIYRLDEDSKPQPAGASELAEVSEDGLTY
                     KIKLREDAKWSNGDPVTAADYVYGWQRTVDPATASEYAYLYAPVENAEDITAGKKDKS
                     ELGIKAVGDYELEIKLTKQTPYFQYLLAFPSFFPQKQSVVEENGDAYASASDKAVYNG
                     PFTLEDFDGPGTDTEWTYKKNDHYWDKDTVKLSEIKVSVVKESSTALNLFKDGQADDV
                     ILSGELAQQNANDPAYTSVKEARTSYIEFNQREKNSPFNNVNLRKAISYSIDREALVK
                     QVLGDGSVVSTGLIPSDMVKSPTTNEDFAKEAGKLVSYDKDKAKEYWEKAKKELGVDS
                     LEFDLMASDDDSSKKVIEYVQNSIQENLDGVTVKPTPVPFSVRLDRSTSGDFDAVLGG
                     WAADYADPSSFTDLFVTGNSYNRGRWSNAEYDEAVKAASSTDAGDEQARWDDFQKAIK
                     IISDDMGVVPVYQKAEGHLVNEKIKGIVHHAAGASWDYKWTYVEE"
     gene            complement(2030..2377)
                     /locus_tag="ACG8LA_001920"
     CDS             complement(2030..2377)
                     /locus_tag="ACG8LA_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3899 domain-containing protein"
                     /protein_id="HFQ0204215.1"
                     /translation="MKKKSIPYAVAFLLILVILIKNLINHSFTLIQLSNDLFLWSLPF
                     LIIGGFLWVFSSGFFDHFQRSVHLARTRNRKKKPEFSSLSSASYGMYSFWLIIAGILI
                     ALSAIFMLFSLLG"
     gene            2461..3402
                     /gene="opp3b"
                     /locus_tag="ACG8LA_001921"
     CDS             2461..3402
                     /gene="opp3b"
                     /locus_tag="ACG8LA_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter permease"
                     /protein_id="HFQ0204216.1"
                     /translation="MNSYIKYVLKRVFFMIITLWLIATITFFLMQLLPGTPYTNQERL
                     SPETIEMLNKQVGLDKPVIVQYGIYLSNLLQGDFGISFQFKNQPVAHLLAGRIGPSLQ
                     LGLQAIIFGTVLGTILGTISAMKQNTWADTSSTLVAILGRSIPNFVFAVLLQYIFAIK
                     LQVLPIAKWDGFVYTILPTIALAMSPLADSARFIRTEMVEVLHSDYVELAKAKGLSRW
                     EIAFKHGLRNSLIPLMTLLGPLAVALMTGSLVVENIFAIPGIGEQFVKSITTNDYPTI
                     MAVTILYSFMLIFVILIVDLLYGLVDPRIRVSEGSRG"
     gene            3403..4446
                     /locus_tag="ACG8LA_001922"
     CDS             3403..4446
                     /locus_tag="ACG8LA_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFQ0204217.1"
                     /translation="MEMIPKRYETVADIPADEFLPLQKNTEEEREQITAPSLNFIQDS
                     WRRLKKNKAAVISMVLLLVIILISVITIFVSPHDPTAQNVAYINLPPRIPGINIDGLN
                     GKAMVGGELVDKYAQANVPSNVNFFLGTDGLGRDVLSRLFMGMRISLLIAFIAALLDV
                     TIGVAYGLVSGLLGGRVDNVMQRFLEILSGIPNLVVMILMLVVFEPGIFSIVAAMAIT
                     NWIPMARIVRAQTMKLKDQEYVLAGLTLGESRMKIAFKHILPNISSVIIIQMMFSIPS
                     AIFFEAFLSFIGLGLTPPSASLGTMLSEGYKTFLYLPYLLWIPAVTLSVIMIGFNLLA
                     DGLRDAFDPKMKE"
     gene            4452..5522
                     /locus_tag="ACG8LA_001923"
     CDS             4452..5522
                     /locus_tag="ACG8LA_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0204218.1"
                     /translation="MTKILEVKDLEISFDTYAGKVRAIRGVNFHLNKGETLAIVGESG
                     SGKSVTTRSIMRLLSSNANIDAGQILFKGNDIVGKSEREMQKIRGKEIAMIFQDPMTS
                     LDPTMPIGKQVAESLRKHNKVSKKEGQKAALELLKLVGIPEAEKRINSYPHQFSGGQR
                     QRIVIAIALVCYPEILIADEPTTALDVTIQAQILELLKEIQTKIDTSIIFITHDLGVV
                     ANVADRVAVMYGGRIVEVGTSEEIFYNPQHPYTWGLLGSMPTLDSANDRLYAIPGSPP
                     DLLNPPKGDAFYPRNEFAMKIDAEQEPPFFELSKTHKAATWLLAPQAPKVTPPEEIQR
                     RWAIFKEKQKHTYGQGGIADAK"
     gene            5512..6465
                     /locus_tag="ACG8LA_001924"
     CDS             5512..6465
                     /locus_tag="ACG8LA_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0204219.1"
                     /translation="MPNKLLEVKGLKQYFNVGKKNEVHAVNDISFHIYEGETFGLVGE
                     SGSGKSTTGRTIIRLNEPTDGEILFDGQDITKIKDKKGLTKFRHDVQMIFQDPYASLN
                     PRMKVRDIIAEGIDVNGLAKSSEERAKKVDDLLRTVGLNPSHGTRYPHEFSGGQRQRI
                     GIARALAVKPRFIICDEPISALDVSIQAQVVNLLQDLQKEHQLTYLFIAHDLSMVKHI
                     SDRIGVMHNGLLLEMGTSDEIYNHGVHPYTESLLSAIPLPDPDHERKRRRIKYQPEPD
                     DGQVRQLREIAPEHFVYATEQEVPYYAKKLKRQKESLLVAN"
     gene            6477..7487
                     /locus_tag="ACG8LA_001925"
     CDS             6477..7487
                     /locus_tag="ACG8LA_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-guided endonuclease TnpB family protein"
                     /protein_id="HFQ0204220.1"
                     /translation="MLKAFKFRMYPTEEQKQQLIRTFGCARFTYNHLLKKRQKSWQQT
                     GVANFSLTPATLKKEYPFLKEVDSLALANAQLNLDRAFRNYFKGRASFPKLKTKKSMW
                     QSYTTNNQTRTIYLENGYLKLPKQKELIKINQHRPVEGSIRSATISARYNEEFYVALL
                     CDVSPVKKESLAKWIGIAYHPKTLIQTSRPLEVTLPKFHQTEEKLQHAQRKLNVKVRS
                     AHHRKIRLDQASNYQKQKRKVMDLYLKQKNQREDYLEQLSGKLVKQYDYLFVESFPKE
                     EAHADFSIHDWHKLITKLRYKSQWYNKKFLLINTDGAEESNSVRKSQVVEKMGRHSVI
                     KG"
     gene            complement(7772..8593)
                     /locus_tag="ACG8LA_001926"
     CDS             complement(7772..8593)
                     /locus_tag="ACG8LA_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HFQ0204221.1"
                     /translation="MNRFASKEEEKLYYEHKASEEEFLNWYQKQERPEYDKPSLTVDI
                     VLMCYNKEEDQLKVLLIQRKGHPYRNSWALPGGFVQKDESTGESVLRETKEETGVVIS
                     KENIEQLHTFSTPNRDPRGWVVTVSYLAFIGEEPLIAGDDAKEVRWFTLERHSNKIHL
                     SSGEVAISLDLVTGESSGKDTLAFDHSQIILKAFNRVVNKMEHEPQVLQVLGKDFTIT
                     EARKVFAKFLGIDYKTIDHSNFKKAMLQYFDEIGERPVGIGRPSKIYQLKPGHHE"
     gene            complement(8690..8968)
                     /locus_tag="ACG8LA_001927"
     CDS             complement(8690..8968)
                     /locus_tag="ACG8LA_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204222.1"
                     /translation="MQKKHLFFTLSIAFLSLAHLIFSYFYIRMYGYFNLHGHLNSFMT
                     AAWILRFIIDVYIVICGFFAIREERYKVLPFYLLFFLFNLILPFIFHI"
     gene            9236..11245
                     /gene="metG"
                     /locus_tag="ACG8LA_001928"
     CDS             9236..11245
                     /gene="metG"
                     /locus_tag="ACG8LA_001928"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0004825 - methionine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006431 - methionyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HFQ0204223.1"
                     /translation="MAEKETFYITTPIYYPSGKLHIGNSYTTIACDAIARYKRLMGFD
                     VFYLTGVDEHGQKIETKAEELGVKPQEYVDKMAADVKKLWKTLDISYDKFIRTTDDYH
                     KAAVQKIFDRLLEQGDIYLGEYEGWYSVSDEEFFTETQLAEVYKDDEGNVIGGKAPSG
                     HEVELVKEESYFFRMSKYADRLLEYYEEHPEFIQPESRKNEMINNFIKPGLEDLAVSR
                     TTFTWGVPVKSDPKHVVYVWIDALSNYITALGYGSEDESLFEKYWPADVQMVGKEIVR
                     FHTIYWPIMLMALDLPLPKKVFGHGWLLMKDGKMSKSKGNVVYPEMLVERYGLDALRY
                     YLLRAVPFGSDGVFTPEDFVSRVNYDLANDLGNLLNRTIAMINKYCDGLVPDYASLVT
                     PFDSELSTTAANVVGRYHDAMEKMEFNTALAEIWVLISRANKYIDETEPWVLAKDEEK
                     KAELNSVMIHLAESLRIAAILLQPIMTETPEKIFNQLGLDSETMNLEGLHFGEFPSGT
                     KVVAKGTPIFPRLDMEEEVAFIQEKMSEGTQTNEDTVKWDPEETELVSTKEKQIKFDV
                     FEKVELKVAEVINCQKVEGADKLLQFRLDAGDSQDRQILSGIAEFYPDPSELIGKKVV
                     IVANLKPRKMRGQISQGMILSAEAPDGSLQVIEAPKSMPNGSEIA"
     gene            complement(11724..12311)
                     /locus_tag="ACG8LA_001929"
     CDS             complement(11724..12311)
                     /locus_tag="ACG8LA_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204224.1"
                     /translation="MDFKRSYPKLADYLSNRVDFSRKEQQQSHWHWFTLILFGLMTVA
                     TLSQKLILLTLFIAIVALIKGPVMILWGMLYSFLVGLFPPIGILLSAIFFLLNIGTFT
                     KNWRMTLVGIYFYFYPFGVMALSEVMHWDNHWFIAGSLLLGLILLHVMLTKLYQHYGI
                     GRTIFWYVFSIPFALLTALLPSRLKTKIKGYHKIK"
     gene            12486..13808
                     /locus_tag="ACG8LA_001930"
     CDS             12486..13808
                     /locus_tag="ACG8LA_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HFQ0204225.1"
                     /translation="MKGKLKREINLFGALATVMGTVIGAGVFFKTAAVTASTQSTSLT
                     LLAWLLGGFLTICAGLTVAELATAIPETGGAVKYIEAAYGKLPSFLLGWAQSLIYFPA
                     NIAALSIIFATQLTNLLQLSTDYLLLIAVITAVSVTGLNLLGTKVGASVQSVTLIVKL
                     IPIAVIVIWGLLTPGQGTVQLFPIEAGKDVTFVEGLSSALLATLFAYDGWLGVGAMAG
                     EMKRPEKDLPKAIILGLSFVTVVYLLINFVFLKTLPIDHLAGNLNAASEASDVIFGGI
                     GGKLVTIGILISVYGALNGYTLTGIRVPYAMALEDELPFSKQLTKLSKKFTVPYVPAV
                     FQLAVACIMMSLGSFDFLTDMLIFVMWLFSLLIFIGVFILRKKAPELPRPYKVPLYPI
                     VPIIAILGAIFILGMTMMTQTKLALIGIGVTLIGIPVYYQKKKKRSEE"
     gene            13963..14739
                     /locus_tag="ACG8LA_001931"
     CDS             13963..14739
                     /locus_tag="ACG8LA_001931"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HFQ0204226.1"
                     /translation="MIFDSHTHLNAEQFNEDIPETIQRAQEMGVTKMAVVGFDTPTIE
                     KSLQLSHDYPNIYSIIGWHPTEAGSYTKEIENKLQEQLTLPKVVALGEIGLDYHWMED
                     PKEVQDKVFRRQIAIAKEMNLPISIHTREALEDTYQILKEEDVRDIGGIMHSFSGDYE
                     WAKRFLDLGMHISFSGVVTFKKALDVQEAAANVPIERLLVETDAPYLAPVPFRGKRNE
                     PGYTRYTVEKIAELRNLPTEEVAAQTWTNAHRLFGLSEHG"
     gene            14732..15301
                     /gene="rnmV"
                     /locus_tag="ACG8LA_001932"
     CDS             14732..15301
                     /gene="rnmV"
                     /locus_tag="ACG8LA_001932"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043822 - ribonuclease M5 activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HFQ0204227.1"
                     /translation="MDKMKIQEIIVVEGKDDTRRLREVVDADTIETIGSAINEEILMQ
                     IEHAQETRGVIVFTDPDFSGEKIRKIIMEAVPQAKHAFLPRTQAKPKKKGSLGVEHAS
                     DAAILEALKKVVTPDISQTAVSEITRQDLLDYGLIAGAQAKEKREKLGDELRIGYTNG
                     KQLEKRLKMFRITPKELAQAMKIVEEQHE"
     gene            15294..16178
                     /gene="rsmA"
                     /locus_tag="ACG8LA_001933"
     CDS             15294..16178
                     /gene="rsmA"
                     /locus_tag="ACG8LA_001933"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000179 - rRNA
                     (adenine-N6,N6-)-dimethyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HFQ0204228.1"
                     /translation="MSEYREIATPSRTKEILLKHGFSFKKSLGQNFLTEPNILRKIVE
                     TAQIDEHTNVIEVGPGIGALTEQLAKHAKQVVAFEIDDRLIPVLADTMQPYDNVTIVH
                     QDILKTDLSTAVRETFHEELPLKVVANLPYYITTPIMMHFLESDLVVDELVVMMQKEV
                     ADRISAEPGTKAYGSLSIAVQYYMEASLAFIVPKTVFVPQPNVDSAILKLTRRDIPAV
                     EVTDEKAFFRLTKAAFQQRRKTLWNNLQHSYGKDDQTKAWLAKSLETAGIDPKRRGET
                     LSLQEFAALSNAMSENMQ"
     gene            16629..17258
                     /locus_tag="ACG8LA_001934"
     CDS             16629..17258
                     /locus_tag="ACG8LA_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204229.1"
                     /translation="MRKNSVRKLTISALLIGMGVIIPMVMPKIMIPPASFTLASHVPL
                     FIAMFFTPGVAVAVALGTTFGFFLTTPVIIALRALSHLVFALIGAWYLQKHPSIVLKN
                     GQFTFANWRFQGFNFVIGVIHSLAEMLVVSIFYFIGNMPETYYSQGYFYTVFILMGIG
                     GLIHSLVDYNIAYFIAGTLSKYFDIPVFTAAKKENRKESIQGYAKKTTY"
     gene            complement(17382..18491)
                     /locus_tag="ACG8LA_001935"
     CDS             complement(17382..18491)
                     /locus_tag="ACG8LA_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0204230.1"
                     /translation="MVEMALKNVYKKYDNAENYSVTDFNLSIKDREFIVFVGPSGCGK
                     STTLRMIAGLEDISEGELNIGGKVMNDVAPKDRDIAMVFQNYALYPHMTVFDNMAFGL
                     KLRKYDKADIKKRVDNAAEILGLTEYLKRKPAALSGGQRQRVALGRAIVRDAKVFLMD
                     EPLSNLDAKLRVAMRAEIAKLHQRLETTTIYVTHDQTEAMTMADRIVIMKDGFIQQIG
                     TPKEVYDTPVNMFVAGFIGSPAMNFFNVTLKNGVITDGHGLKLRIPEGKNKVLVEKGY
                     EGKEVIFGIRPEDIHSEQVALEASPEAVVKSEVVVSELLGAETMLYTKTGSTEFISKV
                     DARDFHKPGEIVDLAFNISKGHFFDKETEQVIKLP"
     gene            18700..19122
                     /gene="mgsA"
                     /locus_tag="ACG8LA_001936"
     CDS             18700..19122
                     /gene="mgsA"
                     /locus_tag="ACG8LA_001936"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008929 - methylglyoxal synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006007 - glucose catabolic process
                     [Evidence IEA];
                     GO_process: GO:0019242 - methylglyoxal biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HFQ0204231.1"
                     /translation="MKIALIAHDRKKPMMVKLATAYKTILEKHELFATGTTGQRITEA
                     TGLPIHRFKSGPLGGDQQIGAMISEDQLDLVIFLRDPLAAQPHEPDVTALIRLSDVYE
                     IPLATNIGTAEVLLRGLEAGFLDFRRIVHEIDKHPLSF"
     regulatory      19309..19407
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01831"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="THF riboswitches regulate genes encoding folate
                     transporters and folate metabolism; They are most commonly
                     found in Clostridiales and Lactobacillales; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="tetrahydrofolate"
                     /db_xref="RFAM:RF01831"
     gene            19445..19981
                     /locus_tag="ACG8LA_001937"
     CDS             19445..19981
                     /locus_tag="ACG8LA_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HFQ0204232.1"
                     /translation="MKKHRLDARMIAIMGLLIALMVTLSRLVAIETPFIKISVTFIPQ
                     VIMGILFGPFWSGIGAVLADLVGMALFSKSAFFIGFTLNAFIEGAIYGFFFYRKEITW
                     KNAILATLSVTLIINLFLTPLWLALMYHVPLFSWVVWAPRLLKTVIWLPIQSIAIYYV
                     GRSIPYKKILRSLAIHAK"
     gene            complement(20021..21784)
                     /locus_tag="ACG8LA_001938"
     CDS             complement(20021..21784)
                     /locus_tag="ACG8LA_001938"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0204233.1"
                     /translation="MKVKKLSLQTLRRFIPYLTAYAKDIWLAVILGIINGIATVVMTL
                     QIGQSIDQMIGEGQVRFNRLFHLLILFGGIVLINVVSQWLIQVLSNRLAYLSVAKLRK
                     DAFAHLNRLPLRYYDQNSHGNIVSRFTNDMDNISIAISAAFNQLFSGVAIIILSFIFM
                     MRLSPLLTLVVLCSTPIIFLVSWIVARASQTNFDRQQRIIGDISGFVTERIGNQKIVK
                     AFQQEEASQQQFELLNADLYEKGQRAQFSSSLTNPSSRFVDHLAYLSIGLVGGLLALK
                     SGSSITVGVISSFTIYSSQFSKPFIELSGITTQLQTAFSGLERAFDLIDQPEEKPDLP
                     DAYALEPKNIKGKVSFDHVSFSYDPKQRLIEDFNFTAYPGQTIAIVGKTGAGKSTLVN
                     LLMRFYDTTKGTITVDDHDIRSIQRDTLRKSFGMVLQDTWLFDSTLRENLRFGNPEAS
                     DAEINDALKASYMYEFVERLPEKLDTKIGGQGLKISDGQRQLLTIARTMISNPPMLIL
                     DEATSSVDTLTEKKIQQAFLAMMEGKTSFVIAHRLSTIKNADQILVMDQGAIVEMGTH
                     DELLQKDGYYRRLYQAQFTAQ"
     gene            complement(21787..23502)
                     /locus_tag="ACG8LA_001939"
     CDS             complement(21787..23502)
                     /locus_tag="ACG8LA_001939"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0204234.1"
                     /translation="MIQLLRYAKDYRKQIILGPFFKFLEAVFELVLPLMMASLIDNGL
                     KMNDRGKIIEMGLWMVAMSVIGLICAIICQYYASVASQGFGTELRNQLIKKINTFSHN
                     ELNHFGTDTLITRMTNDINQLQLALAMVIRLLIRAPFLSIGSVVMAFVIDWEVGLFFL
                     ALLPIFSIILFFIIKKTVPLYQKVQEKLDQLNEHVSQNLSGVRVIRAFAQTKKETEKF
                     DKSTNDLANNYLRVSNISALLSPATTLIMNVGIICLLTVGGIKVNIGSLQQGQVLALI
                     NYMNQMLLALIVVSNLVVIFTRAEASGNRVKEVLDTENSILEAEVSTTPDFSSEAIIA
                     FDHVDFRYTPDSGLSLQNITFQLKRNTVLGIIGPTGSGKTTLTQLIPRFYDVSSGTVI
                     MDGMDVRSWQLDHLRQQIALVPQTSVLFTGTIRENLQWGKKDATEKECWEALKIAQAE
                     EFVRQLPNGLDTKVMENGKNFSGGQKQRLTIARALIAKPALLILDDSLSALDYQTDLD
                     LRKALQTYLGSTVIIISQRVRSIQEAHHILVMDQGKIAAQGTHEELLAQSAEYQEIVA
                     SQEEE"
BASE COUNT         7656 a         4333 c         4810 g         6934 t
ORIGIN      
        1 tcagataagg gactgtgaca agacttttgt cacagtttct ttttgtttat tcttttttat
       61 ctttgtatgg caataataga caatataacg aaaattattt aatggctttt ggaagaccat
      121 ggaaaacctt gtacaaagct attttttctg aaaaattcct tgaaacctca cgaaaaaatc
      181 attattttat gaaaaagaca aaaaaaagtg ttgatttttt aataattatt cattaaactc
      241 ttaaacaact tcagaaaata ttaattattc tgaaaattcc aataaagggg tacgtaaaat
      301 gaaaaagaaa tttacatttg gtttggttgc ggtatgcggc cttgtacttg ctggatgtta
      361 tggcggcagt tcagccacaa gcagtagttc agcaaaaagc ggttcagcag atggaggagg
      421 cgtatttaac ttagtcgtgc ctcaagaaat gcctacagct gacttatcag ttgcaacaga
      481 tacaatcagt tttacagcat tgaataacgt ttatgaagga atttaccgtc ttgatgaaga
      541 cagcaaacca cagccggcag gagctagcga gttggcagaa gtcagtgaag acggattaac
      601 ttacaaaatc aaattacgag aagacgcaaa atggtcaaat ggtgatcctg ttacagcagc
      661 ggattacgtt tatggctggc aacgaacagt agacccagct acagcttctg aatatgctta
      721 cctgtatgcg ccagttgaaa atgcagaaga cattacagct ggaaagaaag ataaatcaga
      781 actagggatc aaagcagttg gtgactatga attagaaatc aaattgacga aacaaacacc
      841 atatttccaa tatctgcttg ctttcccatc atttttccca caaaaacaat ccgtagtgga
      901 agaaaatggg gatgcctatg catctgcaag tgataaagct gtttataatg gaccattcac
      961 attagaagat tttgatggac caggaacaga tacagaatgg acttataaga aaaatgatca
     1021 ttactgggac aaagatacag taaaactttc tgaaatcaaa gtcagtgtag taaaagaatc
     1081 ttctactgca ttgaacttat tcaaagatgg ccaagcagat gacgtgatct tgtctggtga
     1141 gttagcacag caaaacgcaa acgatccagc ttatacttct gttaaagaag cgcggacaag
     1201 ctatatcgaa ttcaatcaac gtgaaaagaa ttcaccattc aacaatgtga acctaagaaa
     1261 agctatttct tattctatcg atcgtgaagc tttagtaaaa caagtactag gtgacggatc
     1321 agttgtctct acaggattga tcccatcaga tatggtaaaa agtccaacaa cgaacgaaga
     1381 ctttgcaaaa gaagctggaa aattagtttc ttatgacaaa gataaagcaa aagaatattg
     1441 ggaaaaagcg aaaaaagaat tgggcgttga ttctttagaa tttgatttga tggcttctga
     1501 tgatgattca tcgaaaaaag taatcgaata tgttcaaaac tcaatccaag aaaacttgga
     1561 tggcgtaaca gtcaaaccaa cacctgttcc attctctgta cgtcttgacc gctcaacttc
     1621 gggtgatttt gacgcagtac taggcggatg ggctgctgac tatgcagacc caagcagctt
     1681 tactgatttg tttgtcacag gtaattcata caaccgtggt cgctggagca atgcagaata
     1741 tgacgaagca gttaaagcag cttcatcaac agacgctggc gatgaacaag cccgttggga
     1801 tgatttccaa aaagcaatca agatcatctc tgatgatatg ggtgtcgttc cggtgtacca
     1861 aaaagcagaa ggtcacctag tgaatgaaaa aatcaaaggt atcgttcacc atgcggcagg
     1921 cgcttcatgg gattacaaat ggacatacgt tgaagaataa tcgttaatac cgtgagcatg
     1981 agaaaaaacg aggctgcggc aaatgtcgca acctcgttct catattcact tatcctaaca
     2041 aagaaaaaag catgaaaata gcagaaagag caattagtat tccggcaatg atcagccaaa
     2101 agctgtacat accgtagctg gcagacgaga gcgaggaaaa ttctggtttt ttctttcggt
     2161 tccttgttcg tgcaagatgg accgatcgct gaaaatgatc gaagaaaccc gaagaaaaga
     2221 cccataaaaa accgccgata atcagaaacg gcaatgacca taagaataga tcattagata
     2281 attgaatgag tgtaaaggaa tggttgatga gattttttat taaaataacc agaatcagta
     2341 gaaaagctac tgcgtagggg atagattttt ttttcatttg attgctcctt tatttttggt
     2401 tcattatcta ataatgtagc gaaacatctg tcagaagtca aaagctaggg ggaaacatta
     2461 gtgaatagtt atatcaaata tgtattaaaa cgtgtctttt tcatgatcat cacgctttgg
     2521 ttaattgcaa caatcacctt tttcttgatg caattgctgc cgggcacgcc atatacgaat
     2581 caggaacgtt tgagtcctga aacaatcgag atgctaaata aacaagtcgg tttggataaa
     2641 ccagttatcg tacaatatgg gatttatctt tctaatttgc ttcaaggaga ttttggaatt
     2701 tccttccaat ttaaaaacca gccagtcgca catttgttag ctggaagaat cggaccatcc
     2761 ttgcagttag ggttacaggc aattatcttt ggaacagtcc tagggacgat tttaggaacg
     2821 atctctgcca tgaagcaaaa tacatgggca gatacatctt ctacactcgt agcgatatta
     2881 ggtcgttcca ttccaaactt tgtatttgct gttttattac aatatatctt tgcaatcaaa
     2941 ttacaagttt tgccaatcgc aaaatgggat ggctttgtgt acacaatctt accaacaatt
     3001 gcgttggcca tgtcgccgct tgctgactct gctcggttta tccgtacgga aatggtggaa
     3061 gtactgcata gtgattatgt ggaattagca aaagcaaaag gattgagccg ttgggaaatc
     3121 gcctttaaac atggtcttcg aaatagtttg attccattga tgactttatt aggaccgtta
     3181 gctgtagcat tgatgaccgg atcactggtg gtagaaaata tctttgctat tcctggtatc
     3241 ggggaacaat tcgttaagtc aatcacaaca aatgattatc ctacgatcat ggctgtaacg
     3301 atcctttact catttatgct gatttttgtt attttgatcg tggatctatt gtacggtcta
     3361 gttgatccaa gaattcgtgt ttcagaaggg agccgaggat aaatggaaat gataccaaag
     3421 cgttatgaaa cagttgcaga tatccctgcg gatgaatttc ttccattaca aaaaaatacc
     3481 gaagaagaac gtgaacagat tactgcacct tctttgaatt ttatccaaga ttcatggcgc
     3541 cgtttaaaga aaaacaaagc tgccgttatt tcaatggttt tactattggt catcattttg
     3601 atctctgtga tcacaatctt tgtttctcct catgatccaa ctgcccaaaa cgtggcttat
     3661 atcaatttgc ctcctcgtat tccgggaatc aatatcgatg gattgaatgg aaaagcaatg
     3721 gttggtggtg aacttgttga taaatatgct caagcaaacg tcccttcaaa cgtaaatttc
     3781 tttttaggaa cagacggttt gggacgtgat gtattaagcc gcttatttat gggaatgaga
     3841 atctcgttgc tgatcgcatt tattgctgca ttactagatg taacgattgg tgtagcttac
     3901 gggttggttt ctggtttgtt aggcggacgt gtcgataacg tgatgcaacg ttttttggaa
     3961 atcttatcag gaattccaaa cctcgttgtc atgattttga tgttggtcgt ttttgaacca
     4021 ggaatttttt caatcgtggc tgctatggcc atcacaaact ggataccaat ggcacgtatc
     4081 gttcgtgcac aaacaatgaa attaaaagat caagaatatg ttttagctgg attgacatta
     4141 ggtgaatcaa gaatgaaaat tgcattcaaa catattttgc cgaatatctc tagtgtcatt
     4201 attattcaaa tgatgtttag tattccatct gctattttct tcgaagcctt tttaagcttt
     4261 atcggtttag gtcttacgcc tccgtcagct tcattaggaa cgatgttgag cgaagggtac
     4321 aagacattcc tgtatctgcc ttatctatta tggattccgg cagtaacttt atcggttatc
     4381 atgattggct ttaacttact tgctgatgga ttgcgtgatg cctttgatcc taaaatgaaa
     4441 gagtgaagac gatgacgaaa attttagaag tgaaagactt agaaatctct tttgatacgt
     4501 atgctggaaa ggtacgagcg attcgcggtg tcaattttca tttgaataaa ggagaaacat
     4561 tggcgatcgt tggggaatct ggaagtggaa aatcagtgac gaccagaagc atcatgcgct
     4621 tgctgtcaag caacgccaat atagatgctg gtcaaatcct ctttaaaggt aacgatatcg
     4681 ttggaaaatc agaaagagag atgcaaaaaa tccgtggtaa agaaatagcg atgattttcc
     4741 aagatccaat gacctcttta gatccgacga tgcccattgg gaagcaagtc gctgagtccc
     4801 ttagaaagca taataaagtt tcaaaaaaag agggacaaaa agctgcatta gaattgctta
     4861 aattagttgg aatacccgaa gctgagaaac gtatcaacag ttatccgcat cagttctcag
     4921 gaggtcagcg tcaacggatc gtgatcgcga ttgcactggt atgttatccg gaaatcctga
     4981 ttgctgatga acctacaaca gcgcttgatg tgactattca agcacagatt ttggagctgc
     5041 tgaaagaaat tcagacaaaa atcgatacat caattatctt tatcactcat gaccttggtg
     5101 tagtagcgaa tgtcgctgat cgtgtcgctg tcatgtatgg aggaagaatc gttgaagttg
     5161 gaacatcgga agaaattttc tacaacccgc aacatcccta tacttgggga ctgcttggtt
     5221 caatgccgac attagatagt gcgaacgatc gattgtatgc tattcctggt tctccaccgg
     5281 atttattgaa cccgccaaaa ggagacgcat tctatccaag aaatgaattc gcgatgaaaa
     5341 tcgatgcaga acaagaacca ccattttttg aactatcaaa aacacacaag gcagcaactt
     5401 ggctacttgc tccgcaggca cccaaagtga caccgccaga agaaatccaa cgtcgctggg
     5461 ctatctttaa agagaaacaa aaacatactt acggtcaagg aggaattgct gatgccaaat
     5521 aaactacttg aagttaaagg attgaaacag tatttcaatg taggaaaaaa gaatgaagta
     5581 catgctgtaa atgacatcag ctttcacatt tatgaaggag aaacattcgg tttagttgga
     5641 gaatctggaa gcggaaaatc cactactggc cgtacgatca ttcgcttgaa tgaacctact
     5701 gatggtgaga tattattcga cggtcaagat ataacgaaga tcaaagataa aaaaggtttg
     5761 acgaaattcc ggcatgatgt tcagatgatc tttcaagatc catacgcttc gttgaatcct
     5821 cgtatgaaag tcagagatat cattgccgaa ggaattgatg ttaatggact agctaaatca
     5881 tctgaagagc gtgcaaaaaa agtcgatgat ctattgagaa ctgttggatt gaatccaagc
     5941 cacggtactc gttatcctca tgaattttca ggtgggcaac gccagcgtat tggtattgca
     6001 cgagcattgg cagtaaaacc gcgttttatc atttgtgatg aaccaatttc tgcactagat
     6061 gtgtcgatcc aagcccaagt ggtcaatttg ttgcaagatc tccaaaaaga acatcaattg
     6121 acctatctat ttattgcaca tgatttgtcg atggttaaac atattagtga ccgaatcggt
     6181 gtaatgcata acggcttgtt attagagatg ggaacaagtg atgaaatcta taatcacggt
     6241 gttcatcctt atacagaaag tttgttatct gctattcctc taccagatcc agaccatgag
     6301 agaaaacgca gaagaatcaa atatcaacct gaaccagatg acggacaagt acgtcaactt
     6361 cgtgaaatcg caccagaaca ttttgtctat gcaactgagc aggaagtccc atattacgca
     6421 aaaaaactaa aacgacaaaa ggaatctctt ctggttgcta actaggaggg acatagatgc
     6481 taaaagcttt taaattccgt atgtatccga cagaagaaca aaaacagcaa ttgattcgta
     6541 cttttggatg tgctcgattt acctataacc atttgctgaa aaagcggcag aaaagttggc
     6601 aacaaacagg agtagccaat ttttcgctca cacccgctac attaaaaaaa gaatacccat
     6661 tcttaaaaga agtagacagt cttgctttag caaatgcaca gcttaatttg gatcgggctt
     6721 ttcgcaatta tttcaaggga cgtgccagct tcccaaagct taaaacgaaa aaaagtatgt
     6781 ggcaatctta tacgaccaac aaccaaaccc gtacgatcta tctggaaaat ggctacttaa
     6841 agttaccaaa acaaaaagaa ctaatcaaga taaatcagca tcggccagtt gaaggatcga
     6901 ttcgctccgc tacgatttct gctcgatata atgaagaatt ttatgtcgca ctactttgtg
     6961 atgtttcgcc agtaaaaaaa gaatctttag ctaaatggat cgggatcgcc tatcatccga
     7021 agacattgat ccaaacatct cgacctctag aagtaacttt accaaaattt caccagacag
     7081 aagaaaagct gcaacatgca cagcggaaat tgaatgtgaa agtccgctcc gctcaccata
     7141 gaaagatcag gttagatcag gcaagcaatt atcagaaaca aaagagaaaa gtaatggatc
     7201 tttatctgaa acaaaagaac cagcgagaag attatcttga acaattatct gggaaattgg
     7261 tcaaacaata tgactactta tttgtagaat cttttccaaa agaagaggca catgctgatt
     7321 tttctattca cgactggcat aaattaataa caaaattgcg ttataagtcc caatggtata
     7381 ataaaaaatt tcttttgatc aataccgacg gagcagaaga aagcaattcc gtaagaaaga
     7441 gccaagtagt agaaaaaatg ggcagacatt cggttatcaa gggataaaaa atgaatgaaa
     7501 ctgataggag cgttagggtt agccttgtta ataaaaagtc ttaatgactt ttgtttctag
     7561 gaatttttct tttgaagaaa agctcactaa ttatgacaaa ccaataaaac aatagcagaa
     7621 aaagttcgta cgagcttttt ctgctattgt taatttttta ttcagaaagt ttacgaatac
     7681 atcaaaattc tgaaacaaaa aacgtaactc acaaagagtt gtttttgcgt tttttcttga
     7741 atgattaggt ctgaatcttt tgctcacaac cttattcatg gtgccccggc ttgagctgat
     7801 agatttttga aggacggccg attcctacag gacgttcacc gatctcatcg aaatattgga
     7861 gcatagcttt cttaaaattg gaatgatcga tcgttttata atcgatccct aagaatttag
     7921 caaatacttt tcgagcttcc gtaatcgtga aatctttacc taaaacttgt agaacttgcg
     7981 gctcgtgttc cattttattg actacacggt tgaatgcttt caagatgatt tgactatggt
     8041 caaaagccaa agtatctttg ccagaagact ctccagtgac taaatcaagc gagatagcca
     8101 cttctccgct agataaatgg atcttgttac tatgacgttc tagtgtgaac cagcgtactt
     8161 ccttggcatc atctccggcg attagcggtt cttctccaat aaaggctaag tagctgactg
     8221 tgacgaccca gcctcgcgga tctcgattag gcgtactgaa tgtatgcagt tgctcaatat
     8281 tttcttttga aataaccaca ccagtttctt cctttgtttc tcttaagacg ctttctccag
     8341 ttgactcatc cttttggaca aagccaccag gcaatgccca tgaatttcga taaggatgcc
     8401 cttttctttg gatcaacaaa actttcagct gatcttcttc tttgttatag cacatcagta
     8461 cgatatcgac agtcaaagag ggcttgtcat attctggacg ttcctgtttt tgataccagt
     8521 taagaaattc ttcttcactt gctttatgtt cataatataa tttttcttct tctttagaag
     8581 caaaacggtt catctgacca cctccattga cagtaaaagt actttttacc ttattgtagc
     8641 agactctgaa aaaaaaccaa ggatttactt gaaaaatcta ggttatcatt taaatatgaa
     8701 aaataaatgg aagtatgaga ttgaataaaa agaaaagcag ataaaacggc aatactttat
     8761 accgctcttc acgaatggca aagaagccac aaataacgat atatacgtca atgataaaac
     8821 gcaaaatcca agctgctgtc ataaaactgt tcaaatgccc atggaggtta aaataaccat
     8881 acatacgaat ataaaaatag ctgaatatta aatgtgctaa tgaaagaaaa gcaatactaa
     8941 gtgtaaaaaa aagatgtttc ttctgcatga ttgttccagt cccttactaa gatagatagt
     9001 ctttattata ccacgtgtga ggggagaaat aaaaagccgt tttttagtag atatgaaaca
     9061 aaacaaaaac ccgcatttat tcaacctatt catcctttta aaggatagat tgaacgtaga
     9121 tagaagtcgt ttatccagtc tttttcattt tgaaaaaaag ctaacagcat gcttttttta
     9181 tggtatacta gcaaggaaac gaattcgcat catgcgataa aggaggaaga gccccgtggc
     9241 agaaaaggaa actttttata tcactacgcc aatctattat ccaagcggca aacttcatat
     9301 cggcaactcg tatactacga ttgcatgtga cgcaattgct cgttataaac ggttgatggg
     9361 ctttgatgtg ttttatctca ctggagtgga tgaacatggt caaaaaatcg aaacaaaagc
     9421 agaagaacta ggtgtaaaac cgcaagaata tgtagataaa atggcggctg atgtcaagaa
     9481 attatggaaa acgcttgata tcagttatga taaattcatt cgcacgacag atgattacca
     9541 taaagcagct gttcaaaaaa tatttgatcg tttattagaa cagggagata tttacttagg
     9601 tgaatatgaa ggctggtact ctgtttctga cgaagaattc tttacagaaa cacaacttgc
     9661 agaagtgtac aaagatgacg aaggtaacgt gatcggtggt aaagcgccaa gtggacacga
     9721 agtagaattg gtaaaagaag aatcatactt cttccgcatg agcaaatacg cagaccgtct
     9781 attggaatac tatgaagaac atcccgaatt catccagcca gaatctcgta aaaacgaaat
     9841 gatcaacaac tttatcaaac caggattaga ggatcttgca gtttcacgaa caacttttac
     9901 ttggggagta ccagtcaaga gtgatccgaa acatgtggtg tatgtatgga tcgatgcatt
     9961 atccaattat attactgcac taggatatgg ctccgaagat gaaagtctat tcgaaaaata
    10021 ctggcctgca gatgttcaga tggtcggtaa agaaatcgtt cgctttcata cgatctattg
    10081 gccaatcatg ctgatggccc ttgatttgcc tctacctaaa aaagtatttg ggcatggctg
    10141 gctattgatg aaagacggaa aaatgtctaa atcaaaagga aatgtcgttt atcctgaaat
    10201 gcttgtggaa cgttatggtt tagatgcact ccgttattat ttgcttcgtg ctgttccgtt
    10261 tgggtcagat ggtgtcttta cgccagaaga ttttgtttcc cgtgtcaatt atgatctggc
    10321 aaatgatcta gggaacttat tgaatcgaac gattgctatg atcaacaaat attgtgatgg
    10381 actcgttcct gactatgcct cacttgtcac tccatttgat agtgaactgt ctacgacggc
    10441 tgctaacgtt gtcggacgtt accatgatgc aatggaaaaa atggaattca atacagcatt
    10501 ggctgaaatc tgggtgctga tttctcgtgc aaacaaatac attgatgaaa cagaaccatg
    10561 ggtattagca aaagacgaag aaaagaaagc tgaattgaat agtgtcatga tccatttagc
    10621 tgaatctttg cgtatcgcag cgatattact tcagccaatc atgacagaaa cgccagagaa
    10681 gatcttcaat caactaggat tggactctga aacaatgaat cttgaaggat tacactttgg
    10741 cgaatttcct tcaggaacaa aagtagttgc aaaaggtaca ccaatcttcc cacgtttaga
    10801 tatggaagaa gaagttgctt ttattcaaga aaaaatgtct gaaggtactc aaacaaacga
    10861 agatacagtc aaatgggatc cagaagaaac agaacttgtt tcaacgaaag aaaaacaaat
    10921 caaatttgat gtatttgaaa aagtagaact aaaagtagca gaagtcatca actgtcaaaa
    10981 agtagaaggg gcagataagt tgctgcaatt ccgactagat gctggagaca gccaagaccg
    11041 tcaaatcttg tcaggaatcg ctgaatttta tcctgatcca agcgaattga tcgggaaaaa
    11101 agtcgtcatt gtagcaaatc tgaaaccacg aaagatgcgt ggacaaatca gtcaaggaat
    11161 gatcctttct gcagaagcac cagatggctc tttacaagta atcgaagcac caaaatccat
    11221 gccaaatggc tcagaaatcg catagaaatt caaagggggt atgacactag ttgtgtcata
    11281 cccccttttt ccgaaatttg agaagcaatt ttcgtaaatt ccttcttatt acttgaagcc
    11341 aatcatataa tacagaaaca gagaactatc caaaataaat cctagaaaaa gaagtacgag
    11401 cttcgctgat ttttgttaat ttagaataat actaatagga atcgtaaaaa cagaaaaaaa
    11461 gcataatgat aaagggtcgg gcagatttta attgattcat ctggtactct tttttattgt
    11521 ccttacattc ataaagtttg aatgcaatga ctttattaca tctatattta tatctaacag
    11581 tagcgttgat gtgttaatta taagttctat cactttatgt tcaattagtt tgtgctctta
    11641 tatgtgtgat tgaaaatata gataaaaaaa caatcatcgg ctttgacttc gatgattgtt
    11701 ttctttattt tgtaaaaatc ctatcacttg attttatggt aaccttttat ttttgtcttc
    11761 aaacggcttg gtaagagagc agtaagcagt gcaaatggga tcgaaaagac ataccagaaa
    11821 atcgtacgtc cgataccata atgttgatag agctttgtca acatcacgtg taacaagatc
    11881 aaccctaaaa gcaaggagcc agctataaac caatgattat cccaatgcat gacttcacta
    11941 agtgccatca ctccaaaagg atagaaataa aaatagatcc cgactaaggt catccgccag
    12001 ttctttgtaa atgttccgat attcaataaa aagaaaatcg ctgaaagcaa aataccgata
    12061 ggcggaaaaa gcccaaccaa aaaggaatac aacatccccc acaagatcat cacaggacct
    12121 ttgatcaatg caacgattgc gatgaacaaa gtcagcaata ttagtttttg tgataacgtt
    12181 gcaacagtca ttaatccaaa taaaattaat gtgaaccaat gccaatggga ctgctgttgt
    12241 tctttacggg aaaaatcgac ccggttggat aaataatctg ctaatttcgg ataagaacgc
    12301 ttaaaatcca taaactgttc ctccttcgtg gaaaaggtag gtttagtata cgaaaaataa
    12361 aaaagaaata catccgtctt aagagggagt ttttcactga aagtggagaa aaaagaatgg
    12421 taaattaaaa tattctcagt tatactgaaa attataccaa atttcaaaga agaaagagga
    12481 tgggaatgaa aggcaaacta aaacgagaaa tcaatctgtt tggcgcatta gctaccgtta
    12541 tgggaaccgt gatcggtgca ggcgtcttct tcaaaactgc tgctgttact gctagtactc
    12601 agtctacaag tttgacattg ctagcttggc ttttgggtgg tttcttaacg atctgtgctg
    12661 gattgacagt ggctgaatta gctacagcaa tcccggaaac tggtggagct gtaaaatata
    12721 ttgaagctgc gtatggaaaa ttgcccagct ttttattagg atgggcgcaa agcttgattt
    12781 actttcctgc taatattgct gcattatcga ttatctttgc gacacaattg acgaacttat
    12841 tacaattatc taccgattat cttttgttga ttgcagtgat caccgctgtt tctgtgacag
    12901 ggttgaattt gttagggaca aaagtcggtg cttctgtaca atcagtgacg ttgattgtta
    12961 aattaatacc aattgctgtg attgtcatat ggggattatt gaccccagga caaggaactg
    13021 tccagttatt tccaatcgaa gctggaaaag atgttacttt tgtcgaagga ttgagcagtg
    13081 cgttgttagc aacgttgttt gcttatgacg gctggttagg tgtcggtgca atggcagggg
    13141 aaatgaaacg gccggaaaaa gatttgccta aagcaattat tcttggtttg agttttgtaa
    13201 cagtcgttta tctattgatc aattttgttt ttttgaaaac tttgccgatt gatcatcttg
    13261 ccggtaattt gaatgcagct tctgaagcat cagacgtcat ttttggagga atcggtggaa
    13321 agctggtcac tattgggatc ttgatctcgg tatacggtgc attgaacggt tatacactaa
    13381 ctgggatccg cgtgccttat gcgatggctt tagaagacga gctacctttc agtaaacagc
    13441 tgacaaagct ttcaaagaag tttacggttc cttatgttcc tgcggttttc cagttagcag
    13501 tagcttgtat tatgatgagc cttggttctt tcgacttttt aacagacatg ttgatttttg
    13561 tgatgtggct attcagttta ctgattttta tcggtgtctt tattttaaga aaaaaagcgc
    13621 cggaattgcc acgtccatat aaagtaccac tttatccaat cgttccgatt attgcgattc
    13681 tcggtgctat tttcatttta ggtatgacga tgatgacgca aacgaaatta gcattgatcg
    13741 gtataggtgt taccttgata ggtatcccag tctattatca aaaaaagaaa aaacgctcag
    13801 aagagtaaaa tatttcaaca acagacagaa aaagtacgaa ctaggtcctc tagatcttcg
    13861 tgctttttct atttcaataa aacaagttct tctattttga tttttgctac ttctgcaagt
    13921 agtgcttatg tgctaaagta agaatgaaaa ggagagataa acatgatatt tgattctcat
    13981 acccatttaa atgctgaaca gttcaatgaa gatattccag aaacgattca gcgagcacaa
    14041 gaaatggggg taacgaaaat ggcggtcgtg ggcttcgata cgccaacgat tgaaaagtct
    14101 ttgcaattaa gccatgacta tccaaatata tacagtatta tcggctggca tccgacagag
    14161 gctggcagtt atacgaaaga aatcgaaaat aaattacaag aacaattgac tttaccaaag
    14221 gttgtagcat taggggaaat tggcttggat tatcattgga tggaagaccc gaaagaagtc
    14281 caagataaag tatttcgcag acagattgct atcgcaaaag aaatgaacct accaatcagt
    14341 attcatacta gagaagcact tgaagacacg tatcaaatcc taaaagaaga agatgttcga
    14401 gatatcggtg gaatcatgca tagtttcagt ggtgattatg aatgggcaaa acgatttctt
    14461 gacttaggga tgcatatttc atttagcggt gtcgtcactt tcaaaaaagc attagacgtc
    14521 caagaggctg cagcaaatgt accaatcgaa cgattacttg tggaaacaga tgccccttat
    14581 ctggcaccag ttccttttag aggaaagcga aatgaaccag gctatactcg ttatacagta
    14641 gaaaagattg ctgaacttcg gaatcttccg acagaagaag tggctgccca aacatggaca
    14701 aatgcgcacc gattatttgg tctaagcgaa catggataag atgaagatcc aagagattat
    14761 agtcgttgaa ggaaaagacg atacaagaag gctgcgggaa gtagttgatg cagatacgat
    14821 agaaacaata gggtctgcaa tcaatgaaga gatcctgatg caaattgaac atgcccaaga
    14881 gactcgtgga gtgatcgttt ttaccgatcc tgatttttca ggagaaaaaa taagaaaaat
    14941 cattatggaa gctgttcctc aggcaaaaca tgcttttttg ccgcgcacac aagctaaacc
    15001 aaagaaaaag ggaagccttg gtgtcgagca tgcaagtgat gctgctattt tagaagcatt
    15061 gaaaaaggtc gtgacgccag acatttccca aacggctgtt tctgaaatca ctagacaaga
    15121 ccttttagac tatggtttaa tagctggggc acaagcaaaa gaaaaacgag aaaaactagg
    15181 tgacgagttg cgcatcggtt acacgaacgg caaacaattg gaaaaacgtt tgaagatgtt
    15241 tcgtattacg ccgaaagaac tcgcccaagc aatgaaaata gtggaggaac aacatgagtg
    15301 aatatcgtga aattgcgaca ccctctagaa caaaagagat tttattgaaa catggttttt
    15361 catttaaaaa aagtttagga caaaattttc tgactgaacc aaatatttta aggaaaatcg
    15421 tagaaactgc gcaaatagat gaacatacga acgtgatcga agttggacca ggaatcggtg
    15481 cattgacgga acaattagcc aagcatgcaa aacaagtcgt agcatttgag atcgatgatc
    15541 gtttgatccc tgtattggct gatacgatgc aaccctatga caatgtgact attgtacatc
    15601 aagatatttt aaagaccgat ttgtcaacag ctgttagaga aacatttcat gaggagcttc
    15661 cgttaaaagt cgtagcgaat ttaccttact atattacgac accgatcatg atgcattttc
    15721 ttgaatcaga tttggttgtg gatgaactag tcgtcatgat gcaaaaagaa gtagctgatc
    15781 gtatctctgc tgaaccagga acgaaagctt atggttcatt atcgattgct gttcaatatt
    15841 atatggaagc cagtttagca ttcatcgtac caaaaacagt atttgtccct cagccaaatg
    15901 tagattcagc gattttgaaa ctgacaagaa gagatatacc ggcagtcgaa gtgacagacg
    15961 aaaaagcatt tttccgattg acaaaagcgg catttcagca aagaagaaaa acgctttgga
    16021 ataacttgca gcattcgtat ggcaaagatg accagacaaa agcatggtta gcaaaaagct
    16081 tggaaacagc tggaatcgat ccaaaacgtc gtggggagac tttgtcatta caagaattcg
    16141 ccgcattaag caatgcgatg tcagaaaata tgcagtaaaa aaagaggttg tgacagaagt
    16201 tgtgaaaaag ctgtcctgca tcaagtaata agaacagcca aacaaaaata gttcctcatg
    16261 tttttcgttt gtttgggctt attaccgcag atgcaagctt ttgaacaccg tttaagaaag
    16321 aggttgtggg cctgccgttt aactctaagt cacaaggaac aatttcaaaa aacagcttct
    16381 catgtttttg agttagttgg tcttattact tgatgcaagc ttttgaccac tattatgccg
    16441 aacaaggaga tgtgacacaa attttgtcac atctcctatt tttgtttctt gatcaaaaaa
    16501 ttcttatact tgatactcac actcattttg tatggattta gaaaagaata tgtgtcttga
    16561 cagttattag taagtgagtt atactaagtc gacatttatg tgtcaagaca tattaggaga
    16621 gagaaaaaat gagaaaaaat tcagttcgaa aactaacgat ttctgcttta ttgattggga
    16681 tgggggtcat tatcccaatg gtcatgccta aaatcatgat tccaccagct tcctttactt
    16741 tggcgtctca tgtgccatta tttattgcga tgttttttac accaggagtt gcagtggctg
    16801 ttgcgctagg tacgacattt ggtttctttt taacaacgcc ggttatcatc gcattgcgag
    16861 cattgtcaca tcttgtgttt gcgttgattg gggcttggta cttgcaaaag catccgagta
    16921 tcgttttaaa aaatggacag tttacttttg ctaattggcg tttccaaggg ttcaattttg
    16981 tgatcggtgt gattcattct ttagcagaaa tgctagtagt cagcatcttt tactttattg
    17041 gtaatatgcc tgaaacatat tattctcaag gatattttta tacagtattc atcttgatgg
    17101 ggattggtgg gcttatccac agtttagttg attataatat tgcttatttt atagcaggaa
    17161 cactcagcaa atattttgat atccccgtat ttacggcagc aaaaaaagaa aatcggaaag
    17221 agtcgattca agggtacgcg aagaaaacga catattagac atgatctctc aaaaaaaaaa
    17281 ctctcatcta gtaatggata ataaatcctc taagatgaga gttttttgtc ctaaaaagag
    17341 ctgcaccaac atcttctggc acagctctaa cagggggcaa tttatggaag tttgatgact
    17401 tgttctgttt ctttatcaaa gaagtggcct ttgctgatgt tgaaggcaag gtcgactatt
    17461 tcgcctggtt tatggaaatc tcttgcatct acttttgaga tgaactcagt agaaccagtt
    17521 tttgtgtaaa gcatcgtttc agctccaagt aattcggaaa cgacaacttc tgatttcact
    17581 acggcttcag gtgaagcttc aagggctact tgttcactgt ggatgtcttc tggacgaata
    17641 ccgaagataa cttcttttcc ttcataacct ttttcaacta atactttgtt ttttccttca
    17701 ggaatacgaa gcttaagccc atgtccatct gtgataacac catttttcaa tgtcacatta
    17761 aagaagttca tggcaggaga tccaataaag ccggcaacga acatattgac gggtgtatca
    17821 taaacttctt tcggtgtacc gatttgttgg ataaatccgt ctttcatgat aacgattcgg
    17881 tcagccatag tcattgcttc tgtctgatcg tgagtaacat agatggtcgt tgtttcaaga
    17941 cgctggtgaa gtttggcaat ctcagcacgc atggctacac gtaatttagc atctaaattt
    18001 gataatggct catccattaa gaagactttt gcatcccgaa cgattgcccg tcccaatgcc
    18061 acacgttggc gttgtccacc agataaagca gctggttttc gtttcaagta ttctgtcaga
    18121 cctaagatct ctgctgcatt gtccacacgt tttttgatgt ctgctttatc atatttacgt
    18181 aatttcaagc caaaagccat attatcaaaa acagtcatat gaggatacaa tgcgtagttt
    18241 tggaaaacca tggcaatatc acggtcttta ggtgccacgt cattcatgac ttttccgccg
    18301 atatttagtt ctccttcaga gatatcttcc agtcccgcga tcattcgcaa agtagttgac
    18361 tttccacaac cggaaggacc aacaaaaacg ataaattcac ggtctttgat tgatagatta
    18421 aaatcagtta cagaataatt ttctgcattg tcatattttt tatatacgtt tttcagagcc
    18481 atttctacca taatacgttc cacactttct tttttagttt tattaactat ttaaagtata
    18541 aatgaaagcg ttaactaact tcaatgtcat gttgaacaag aattttttct tttttttgtc
    18601 aatgtgctag ttttaagctt taataaatat ccataagaaa taaaaactga tacactggag
    18661 taaataagta tgttaacaat atcaaaagga gtgtctctta tgaaaatcgc tttgatcgct
    18721 catgaccgaa aaaaacctat gatggtgaaa ttagcaacag cgtataaaac aatattggaa
    18781 aaacatgaac tttttgctac cgggacgact gggcagagga tcacggaagc aaccggcttg
    18841 ccgatccatc ggtttaaatc cggaccgtta ggcggggatc agcaaattgg agccatgatt
    18901 tcggaggatc agttagattt ggtgattttt cttcgagacc cgctggctgc acagccccat
    18961 gaaccagatg taacagcact tatccgttta tctgatgtct atgagattcc gttagctacg
    19021 aatatcggaa cagctgaggt gctactaaga ggactggaag ccggcttcct agattttcga
    19081 agaatcgtcc atgaaataga caagcatcca ctttcatttt gatggataag cgtatggaaa
    19141 aataacgttt aatgttcgcc tatatgtagc tataaaagct aaacaaactg ataatatgcg
    19201 atataatacg aacgtattgg ataatataaa caataatatt agtttttcgt atttgcagta
    19261 aatgtgaaaa tatgctatag tttctgtggg aaaagatccc aaaaataata cagagtagaa
    19321 aataaagcgt taagtgctaa gaggatggga tgttgcctct tggacgaagg acgtaatgtt
    19381 cgcggtttta ttttcgcatt cgctgcatga tacgatgtag cagctcttaa aggagatgct
    19441 aaaaatgaag aaacaccggt tagacgcacg tatgattgct attatgggct tattgattgc
    19501 attgatggtc actttgtccc gactggtagc aatcgagacc ccatttatta aaatcagtgt
    19561 cacatttatt ccacaagtga tcatgggcat tctttttggt cctttttggt cagggatagg
    19621 cgcagtttta gctgatttag taggaatggc cctcttctcg aaatctgcat tctttattgg
    19681 atttacattg aatgcattta ttgaaggagc aatctacgga ttctttttct atcgaaaaga
    19741 gatcacttgg aaaaatgcca ttctggctac gcttagtgtc acgctgatca tcaacttatt
    19801 tttgacacca ttatggcttg cgttgatgta ccatgtgcca ttgttcagct gggtcgtttg
    19861 ggcgccccgc ctgttaaaaa cagtaatatg gttaccgatt caatcaattg ccatttatta
    19921 cgtaggacgt agtattcctt acaaaaaaat tttaagaagt ttagcgatcc acgctaaata
    19981 aaaaacaagc agtcttccca tcccagaaga ctgcttgttt ttattgtgct gtgaattgtg
    20041 cttgatagag ccgtcggtaa taaccatctt tttgaagcag ctcatcatgg gtgcccattt
    20101 cgacaatagc tccctgatcc atcactaata tctggtccgc atttttgatt gtggacaggc
    20161 gatgggcaat cacaaaactg gtttttcctt ccatcattgc taagaaggct tgttggattt
    20221 ttttctctgt caatgtatcg actgagctgg tagcttcatc taagatcaac atagggggat
    20281 tactgatcat cgttcgagca atcgtcaaca gttggcgttg tccatctgat atctttaacc
    20341 cttgaccgcc aatcttagta tctaattttt ccggcaaacg ttctacaaat tcatacatat
    20401 aagaggcttt tagggcatca ttgatttctg cgtcacttgc ttccggattc ccaaaacgaa
    20461 gattttctcg caatgtactg tcaaatagcc aagtatcttg taacaccatt ccaaaacttt
    20521 tacgtaatgt atcacgttgg atagagcgga tgtcatggtc atcgactgta attgttcctt
    20581 ttgttgtgtc ataaaaacgc atcagcaaat taacaagtgt ggattttccg gcccctgttt
    20641 ttcctactat agcaatggtt tgacctggat aagcagtaaa attgaaatct tcgatcaaac
    20701 gctgcttggg gtcataagaa aaagaaacat gatcaaaaga gacttttcct ttgatatttt
    20761 tgggttccaa ggcataggca tctggcaaat caggcttttc ttctggctga tcgatcaaat
    20821 caaatgctcg ttctagacca gaaaaagcgg tttgcagttg tgtcgtgatt ccagaaagtt
    20881 cgataaatgg tttagaaaac tgacttgagt agatcgtaaa gctggaaatc acaccaacag
    20941 tgattgacga accactcttc aatgccaata ggccgccaac taaaccaatc gataaataag
    21001 caaggtgatc tacaaaacga gaagacgggt ttgtcaagga agaagaaaat tgtgcccgtt
    21061 gtcctttttc atatagatca gcatttagca gttcaaattg ctgttgacta gcttcttctt
    21121 gctgaaaagc tttcacgatt ttctggttac cgattcgttc ggtcacaaag cccgagatat
    21181 ccccaataat cctttgctgt ctatcgaaat ttgtttgtga agcacgagca acgatccaac
    21241 tcacaaggaa aataattggt gtagaacaaa gaacgaccaa tgtcagaagt ggacttagac
    21301 gcatcataaa aataaacgaa agaatgatga ttgccactcc agaaaataat tgattgaagg
    21361 ccgcagaaat tgcaatggaa atattgtcca tatcatttgt aaatcgactg acgatatttc
    21421 cgtgggagtt ttgatcataa taacgaagtg gcaatcgatt cagatgagca aatgcatctt
    21481 ttcttaattt tgcaacggat aagtaagcta accgattgct taacacttgg atgagccatt
    21541 gactgactac gttgattaaa acgataccac cgaatagaat aagtaaatgg aacagtcgat
    21601 tgaagcggac ctgtccttct ccaatcattt gatcgatact ttgaccaatt tgtaacgtca
    21661 tcacaactgt tgcaatccca ttgatgattc ctagtatcac agctagccaa atgtcttttg
    21721 cataggcagt aaggtaagga atgaatcggc ggagcgtctg caaggataat ttttttactt
    21781 tcataactat tcttcctcct gtgatgcgac gatttcctga tattctgctg attgagcaag
    21841 taattcttca tgggtaccct gagcagcaat cttaccttga tccatcacta agatatgatg
    21901 tgcttcttga atagagcgga cacgttggga gataataatc actgtactgc caagataagt
    21961 ctgtagcgcc ttacgcaaat ccaagtctgt ttgataatcc aacgcactta aagagtcatc
    22021 taaaatcagt aatgctggct tggcaatcaa agctcttgca atcgtcagtc gctgtttttg
    22081 tccgccagag aaatttttcc cattttccat gacttttgta tctaaaccat ttggaagctg
    22141 acggacaaat tcttctgcct gagcgatttt cagagcttcc caacattctt tttctgtggc
    22201 gtctttctta ccccattgaa ggttttcacg aatagtcccg gtaaatagta cagaagtttg
    22261 gggaacaaga gcaatttgct gacggagatg atccagctgc caagaacgaa catccattcc
    22321 gtccattata actgtaccgg aactgacatc atagaaacgc ggaatcaatt gtgtcaaagt
    22381 cgttttcccg cttccggttg gaccaatgat tccaaggact gtatttcgct tcagctgaaa
    22441 tgtaatattt tggagagaaa gaccagaatc aggagtataa cggaagtcaa catggtcaaa
    22501 agcgataatt gcttcagaag aaaaatcggg agtagtactg acctcagctt caagaatcga
    22561 attttctgtg tctagcacct ctttcacccg atttcctgaa gcttcggcac gtgtgaagat
    22621 cacgacgagg tttgaaacaa cgatcagtgc caaaagcatt tgattcatat aattgatcaa
    22681 agcaagaact tgtccttgtt gcaagctacc aatatttact ttgatcccgc caactgtcag
    22741 caaacagatg atcccgacat tcatgatcaa ggttgtagca ggtgataata gggcagagat
    22801 attggaaaca cgtaaataat tgttcgctag atcatttgtg cttttatcga acttctctgt
    22861 ttcttttttt gtctgcgcaa atgcgcggat gacacgaaca ccgctaagat tctgactaac
    22921 gtgttcattg agctgatcta gtttttcttg cactttttgg tagagaggaa cggttttttt
    22981 gatgataaaa aataaaatga ttgagaaaat aggcaataat gctaagaaaa acagacctac
    23041 ttcccagtcg atcacaaaag ccatgaccac tgacccgata cttaaaaacg gtgctctgat
    23101 caataaacga atgaccattg ctaaagctag ctgaagctga ttgatgtcgt ttgtcattcg
    23161 ggtgatcaag gtatctgttc caaaatgatt caactcgttg tgagagaaag tattgatttt
    23221 tttgattagc tgattacgta actctgtacc aaatccttgg gaagctactg aagcatagta
    23281 ttggcaaatg atagcacaaa tcagaccaat cacagacata gcgaccatcc ataagcccat
    23341 ttcaatgatt tttcctcggt cattcatttt tagtccatta tcgatcaagg aagccatcat
    23401 taaaggcagg acaagttcga agacagcttc aagaaatttg aagaacgggc ccaaaatgat
    23461 ttgcttacga tagtcttttg cataacgtaa taactgaatc atatgattcc tcctattatt
    23521 tatttgtcca caattgaaaa aacaagtact accacattgt agcttaggaa atttagaatg
    23581 aaaagagaac aagccttttc ataaatgaaa gttttattat gaagaagctt tagaaattga
    23641 atagactatt ttttttaaaa aaaagaaaat gagaaaacat gccagtctct tcattcatag
    23701 gaacgtctat tttacttaat ttttctataa atg
//
LOCUS       DAZKKZ010000047        23249 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.048, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000047 DAZKKZ010000000
VERSION     DAZKKZ010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23249)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23249)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23249
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.048"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(207..488)
                     /locus_tag="ACG8LA_001940"
     CDS             complement(207..488)
                     /locus_tag="ACG8LA_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0204235.1"
                     /translation="MKSEIQVILPSDLDQELRRYFYRVAKEAVDQVRIETSLSKEVFR
                     LGEACKYLSCSRSTLKKFIREKGLKVSIIGDCQFIRKEELARFIKEYEV"
     gene            complement(539..745)
                     /locus_tag="ACG8LA_001941"
     CDS             complement(539..745)
                     /locus_tag="ACG8LA_001941"
                     /inference="COORDINATES: protein motif:HMM:NF013540.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFQ0204236.1"
                     /translation="MKPKDFRKFCGLSQSELAEKYGISVQAVRNKESGKTNYSPEEMI
                     ILKYLVKEKGIENITIDQIFFNEK"
     gene            909..1640
                     /locus_tag="ACG8LA_001942"
     CDS             909..1640
                     /locus_tag="ACG8LA_001942"
                     /inference="COORDINATES: protein motif:HMM:NF024252.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFQ0204237.1"
                     /translation="MFDKNINSEIGKRIQEIRVSLGYTLEEFGENLTPPASKSNVSRW
                     EKGKNIPNKARLLSIAKLGGVSTEYLLTGNSQKTKKYIKYLFNEIFFDNGTFHNKFKD
                     FGKDRDRLGLYDLFLAVSKTYSLDKSPSLKDNFVEMIIDDVYKKLLQTDKSDDQLILG
                     FIYICLDEKLSNRQKSLKSINYEVFNYLGVAFGLIDSEIKSTNAGNDEDLLNYLKELT
                     SFIDEIKTTTFNKKKYFQNQYDIEE"
     gene            1694..2839
                     /locus_tag="ACG8LA_001943"
     CDS             1694..2839
                     /locus_tag="ACG8LA_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFQ0204238.1"
                     /translation="MATIKQYEKKDGTKAWMFQTYLGISPLTGKEVRTTRRNFKTKKE
                     AQIELNRLLVDFEENGLKRETNETFQEVYDLWYESYKTTVKEVTQLKIEIKFNKWILP
                     KYGQFRIKEITTKHVQKILNQWAKTTDQYKVLHSTVSRIFKYAMTLGLITKNPCELVI
                     MPNRNVEKKKDTVKIYSRDQLETLFQYLESKRSTYRAEYDKTLLRFLFFSGCRISEAL
                     ALDWSDIDFDSNTVTINKTLSQTKYGYKISSPKTRNSYGSLSLDNKTINWLKKWQINQ
                     KRYMLTLGITDPTMIFCGIYKEIITKHAIYSRMITICKNSGIPFLGNHVTRHTHASML
                     LESGVSMKEVQERLRHSSIKLTMDTYAHLTKETKEKTVEKLAEHLNF"
     gene            complement(2924..3229)
                     /locus_tag="ACG8LA_001944"
     CDS             complement(2924..3229)
                     /locus_tag="ACG8LA_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002419177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HFQ0204239.1"
                     /translation="MTEHNHSHDHEGHEHITLVDDQGNETLYEILLTVDGQEEFGRNY
                     VLLYPAGVSEDEDVELQAYAYIENEDGTEGELEQIETDAEWDMIEEVFNTFMAEEEE"
     gene            complement(3254..3685)
                     /gene="ruvX"
                     /locus_tag="ACG8LA_001945"
     CDS             complement(3254..3685)
                     /gene="ruvX"
                     /locus_tag="ACG8LA_001945"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HFQ0204240.1"
                     /translation="MRVMGLDVGSKTVGVAISDPFGWTAQGVEIIRINEAEEEFGFDR
                     LKELVAQYEVDRFVVGLPKNMNNSIGPRAEASMSYGEKIKELFSLPVDYQDERLTTVQ
                     AERMLVEQANTSRAKRKKVIDKLAAVMILQNYLDGSGKQLF"
     gene            complement(3682..3948)
                     /locus_tag="ACG8LA_001946"
     CDS             complement(3682..3948)
                     /locus_tag="ACG8LA_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HFQ0204241.1"
                     /translation="MGFTDETVRFGFDDSRKKEVSETLAIVYRALEEKGYNPINQIVG
                     YLLSGDPAYIPRYRDARNLIRRHERDEIMEVIVKDYLSNHGVNL"
     gene            complement(4203..4928)
                     /locus_tag="ACG8LA_001947"
     CDS             complement(4203..4928)
                     /locus_tag="ACG8LA_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HFQ0204242.1"
                     /translation="MSKKTTKAIVGIVAAVIAGAFGVSTTQKDSDIFQQITTIFDSTP
                     QASQVADVPEYDGKHQEIEINGNQPEFTKEDLSLSKGTWESYSNIDKLNRVGQANAML
                     GKDLFPTEKREPLYIDPTGWKQKKLSDGQWLYNRSHLIGFQLTGQNNNIKNLMTGTRS
                     LNAPYMLAHENDIAAYIKETNHHVRYRVTPHFEGNELVARGVQLEAESIEDKKIEFNV
                     FIYNVQDGYTINYETGQATKTKN"
     gene            complement(5289..5359)
                     /locus_tag="ACG8LA_001948"
     tRNA            complement(5289..5359)
                     /locus_tag="ACG8LA_001948"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5325..5327),aa:Gly,seq:ccc)
     gene            5476..6228
                     /locus_tag="ACG8LA_001949"
     CDS             5476..6228
                     /locus_tag="ACG8LA_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HFQ0204243.1"
                     /translation="MTGKELDLLLDTCLLAGKIMMESNAEMYRVEDTMSRIALASGNF
                     RLVSYVTQTGLFIGLDRTSTIRMEQITNRSINLEKVVKVNDLSRKYVASELTLEELYC
                     ELQAIDRDRSFFPVWLQIVSAAVISGTIMVLFGGKMTDLPVTLVIGGLGYAAYLYSLK
                     FFRIKFLSEFLSSLLIGIAAIYSVRFGLGSNQDLIIIGCVMPLVPGVQITNAIRDLLA
                     GHYVSGVSRGTEAMMTATMIGFAIAFIFQLFY"
     gene            6244..6723
                     /locus_tag="ACG8LA_001950"
     CDS             6244..6723
                     /locus_tag="ACG8LA_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HFQ0204244.1"
                     /translation="MGTIFIQFSFSFLATAAFAVITNVPRRSLICCGLSGAFGWMIYW
                     ICVQIGGSAAFGSLLGSLGVAFISDLFSKRLKMPVTIFNIPGMVPLVPGGLAYQAVRN
                     LVTESYREAAHYAVQAIMIAGAIALGLVLSEVFNHNIRNFKVKRDAIMMKRKKRLFK"
     gene            complement(6974..8554)
                     /locus_tag="ACG8LA_001951"
     CDS             complement(6974..8554)
                     /locus_tag="ACG8LA_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HFQ0204245.1"
                     /translation="MYKRQLLELIRVNLLYVNPQLTNKAREKGKKGKRLTIYLLSQNL
                     FSGLIFLLIYGFAMFAMNFVKLPGFFTYYVALFGMLGLTQSISVIYNIFFEGNDLQVF
                     LPLPFGQEQVFSAKILVVALTIIPFVFPLLVMFILTGWRADLGILLTIIISILLFSLF
                     LIILFCLASLIVFGLARTAVFKKHRKTVSSILLGSSMLIAFAGIMWMNHQTGTIENEL
                     TDRHPISILLPFYDAASQPLSQQGLLGWGILAITALGFFLAVKQLIVPKLTEQLTDSN
                     SEFKIKRTHKKNQNVHQLLFSYNAQLVKEPNLIMQVLSSSLLTPIIFILAFALGGEIK
                     LTDLDNKLIGVVFLVGIALAFLTVNQTSFISNLISLDQENFLFIRSLPISMNQYLKEK
                     FRFGWILQSFLTGGIALLSGLSFQLPLFFIPSLLFGSLFGCYLLSLRYFARDYRLLLL
                     NWTNINQLFNRGSGSLGLVATMMGSLIISIILIVLYGMLALFYPFWLVNIPVIGLVLI
                     LSALWIVYYQRTFWKKFE"
     gene            complement(8547..9290)
                     /locus_tag="ACG8LA_001952"
     CDS             complement(8547..9290)
                     /locus_tag="ACG8LA_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0204246.1"
                     /translation="MIEFINVSKSYGKKQALKDLSLSIRQGEIFGFLGHNGAGKSTTI
                     KSLVSIIEPSSGTILVDGMKLTENRLSIKQKIGYVPDSPDIFLQLTAGEYWDLISAAY
                     ELDTQKKEKRLAELTALFDMYSHQNETIASFSHGMRQKTILIGTLLPDPDIWVLDEPL
                     QGLDPQAAFDLKEMMKAHAAKGKTVIFSTHVLDTAQQLCDKLAILKKGELIYQGAVSE
                     LLNGSPDETLEKIYLKMAGRQATGDGPYV"
     gene            complement(9466..10242)
                     /locus_tag="ACG8LA_001953"
     CDS             complement(9466..10242)
                     /locus_tag="ACG8LA_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytR/AlgR family response regulator
                     transcription factor"
                     /protein_id="HFQ0204247.1"
                     /translation="MVTRIFILDDSLVFEKMLVEILEESRILLSPWKFEIVQGLNVIQ
                     FVEFIKNNEIYSSDIFFLDIDLNAYYSGIELGEMLREKNEKCKIVYLTSHPNKAITVI
                     NRKITPSGYLIKEFTYEKNKKSIQSYLLKEKENYPVQHATKKRWTTVRYGNSDHYIHY
                     DEILYLMSMPGYKNKIGLVLKDEEILVNGTIKKYKKSLEYEYLCKDLKAYIINTENIT
                     SISRVNEIVTFANGEQLEMGKRSIDKLKNFMQEKIENESF"
     gene            complement(10490..11326)
                     /locus_tag="ACG8LA_001954"
     CDS             complement(10490..11326)
                     /locus_tag="ACG8LA_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HFQ0204248.1"
                     /translation="MLRFLILSGYFELMMYLQVSGKLDQYINVHYRYLAILSMILSAL
                     LALVQLYLWVKNGKAEEKAHEHDHDHGLSKPYQRGIAYVLLALPVIVGTLFPTVSLDT
                     TIVEAKGFNFPVSKESVGDPEMQTQYLKPDTSIYFNKSDYLDQMNELKEKYGDKQTIK
                     ITDENYLEVMELIYNYPSEFIGKKISYEGFVYQTPNDSNTDIFLFRFGIIHCVADSGV
                     FGLLTHMPEGVTVKNDEWYKIEGTIQSDYYQPFKREIPSVVVTNAEKVSAPKNQYVYR
                     SF"
     gene            complement(11337..12266)
                     /locus_tag="ACG8LA_001955"
     CDS             complement(11337..12266)
                     /locus_tag="ACG8LA_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HFQ0204249.1"
                     /translation="MFSFIPNSVLQMSTIFLSIVIEALPFVLLGCLISGALQVFLTPE
                     RVKRWLPENRIFSIFTGSILGFFFPSCECGIVPIVHQFVKKGVPVHTAFAFMLTAPII
                     NPIVIFSTFIAFGNSWQMASWRVIGSFFVALVIGVWLAYFQKDAVLKEKITSKVAENH
                     HHHVHEEEQSEKNEPKNQLIHQTGHVLTHSIDEFFDTGRYLIIGGLIAAAMQTYLPTR
                     IMLTLGSTKILAIIIMLLLAFTMSLCSEADAFIGSSLLSLFGTAPVAAFLVFGPMVDI
                     KNLLMMKRYFTGRFILSLIGLIALSVIGFTLFI"
     gene            12458..12811
                     /locus_tag="ACG8LA_001956"
     CDS             12458..12811
                     /locus_tag="ACG8LA_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HFQ0204250.1"
                     /translation="MKQTTNLTEVQDILQQSSVAVIYLSMPNCSVCHAVRPRLEELLT
                     HYDIPALHLDAFETPEVASKFEVLTAPVVLIFHQGKEVFRQARFIDFKKIRYLLDELT
                     AEDDSLSYEEIFRTK"
     gene            complement(12885..13541)
                     /locus_tag="ACG8LA_001957"
     CDS             complement(12885..13541)
                     /locus_tag="ACG8LA_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA];
                     GO_process: GO:0051775 - response to redox state [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HFQ0204251.1"
                     /translation="MKDHIIPKATAKRLPLYYRYLRILNNAGKKKVSSTELSEAVQVD
                     SATIRRDFSYFGELGKRGYGYDVEDLMHFFAKTLNDDQLTNVALIGVGNLGSALLKYK
                     FHQSNSIRISCAFDVNEEIVGRIVDGIPVYPMEDMSEQIKIQQIEVAILTIPAERAQE
                     VVNQLTEAGIKGILNFTAARLNAPSDVLIQNVDLTNELQTLIYFLHSDANAHSENTAE
                     "
     gene            13767..15701
                     /locus_tag="ACG8LA_001958"
     CDS             13767..15701
                     /locus_tag="ACG8LA_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HFQ0204252.1"
                     /translation="MILLQANQIARHFGAEVLFENIHLEISTGARVALVGRNGAGKST
                     LLKIIAGIEAPDEGKIAKNKTATLGYLAQDTGLDSNETVWNEMLKAFEQVRQMEERMR
                     ELEIFISEGTPDTPAYSSYLKEYDRLQHDFSDRNGYGYENEIRSVLHGFKFDSSFYDQ
                     KIDTLSGGQRTRLALARMLLQHPDILILDEPTNHLDIETLSWLENYLQSYTGALLIVS
                     HDRYFLDKVVNEVYELSRRKMRHYKGNYSKYLDLKAEQLASEWKAYEKQQTEIHKLED
                     FVARNLVRASTTKRAQSRRKTLEKMDRLDRPQGDEKQANFLFSIEKPSGNVVLQIEDA
                     AIGYDNVTLSEPINLDIRRQEAIALVGPNGIGKSTLLKSIIHQIPFIRGKETLGTNVT
                     IGYYDQGQADLHTNKTILAELWDEHPTTPEKEIRSALGAFLFSGEDVEKPIPLLSGGE
                     KARVALAKLAMNKENFLILDEPTNHLDIDNKEVLENALIDYDGTLLFVSHDRYFINRI
                     ATKVVELSENGSKVYLGDYDYYLEKKQEEEEIAELLAQDEPESAPAPTNKSDYYQSKE
                     QQKLIRSLQRKITQVEEEMARIDEWIDQLEQEMVAPENLEDHVKLNELNQDLEAARQD
                     QETKLTEWEELSLELEEYEN"
     gene            complement(15787..17010)
                     /locus_tag="ACG8LA_001959"
     CDS             complement(15787..17010)
                     /locus_tag="ACG8LA_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HFQ0204253.1"
                     /translation="MLKAGGEMLDKVMFEEIIHPEKWINECYKELMEKEWNNEIERCR
                     RHTERLIKRISNSQYQFPSECPIKGRYPLRDNIGWTEGFWTGINWLLFEKTGDPLFQQ
                     TAEKADIDFIHRIDCQIITNHHDLGFLYSLSTVADYKITGNRKMKEASIDAAETLLQR
                     FWEKAGVIQAWGDPSDPSQQGRMIMDCCMNLPLLYWASEETGNQKYKKAAQAHIQNAA
                     DYLVREDGSTYHTFYMDVKDGKPRYGSTHQGYSDNSCWARGQAWGIYGFALSYRYLKE
                     QKYFDLSKILANYFMNRLPEDTICYWDLIFDDSSREEKDTSSMVIMVCGLLELIESGL
                     LDKTEKNLYQSAVWKIMRQLKERYATTEEEDGFLTQSVYNKPKNNGVNTPCIWGDYYY
                     LEALVRMTSNWSSYW"
     gene            complement(17004..18875)
                     /locus_tag="ACG8LA_001960"
     CDS             complement(17004..18875)
                     /locus_tag="ACG8LA_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2264 domain-containing protein"
                     /protein_id="HFQ0204254.1"
                     /translation="MKHPVPLLRTRQDYFDLFKKINQPLQPFYRASGAQIDYIHQGVG
                     YGNKIAGMEGFSRVLWGAGPAIDQLDERWLKLILSGIKAGTDPSHPDYWGEIHERDQR
                     MVEMPAMLLALYHHEQLLWKKLDTGEKSQIIHWFSQIFEYECADGNWQFFKIIVGTII
                     QKFGYPVKESALKEAFDNIENCYLQNGWYRDSSRGRQDYYNPFAFHYYGLIYSVLEPE
                     KPISQIYKNRAIDFSRDYIHFFAEDGANVPFGRSMIYRFAVSSFWSAMLWADLLPFKL
                     GEIKGLVNRNIRWWMQKEIFDEKGILNIGYTYPQLTLTEPYNSTLSPLWLNKIFLLLA
                     LPEDHEYWTAKEMPMPIREGTKLLSEANLLIQHDNGHTFFLNAGQLGPNFHTLTNEKY
                     LKFAYSSQFGFSIPRANQLKAEMAMDSMLGIQRADTYITTSFKNESIKTYGQFIVRNN
                     VRDIVCKKEVLASTWEPTLQAKIRTWLIPFEGWQIRVHKVELDTEYVLYETGFAIECS
                     PEKEGIIIEEDKENYRVSEAGFSGIICLSDDTIKRKSTAIMGLPNTNLMTWENTFIPG
                     LEGTFGKGTHWLGTGVVAHQDRDYSLEVWNNRPKIDFDGTTGLTIQNKNNKKRLKLC"
     gene            complement(18896..20014)
                     /locus_tag="ACG8LA_001961"
     CDS             complement(18896..20014)
                     /locus_tag="ACG8LA_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HFQ0204255.1"
                     /translation="MNEQTKEWSRKILNVASEKIDAELDRMGNKIPYISYNGKYTDVI
                     KDRGIDWWTNGFWSGILWQLFHKTKREKFKEAAIQQEQLLESALYHFSDVHHDVGFLF
                     LPSAIAHYQQSQNKHSRQLGLHAATVLAGRYNISGNYLVAWNDHKPGWMIIDSMMNLP
                     LLYWASRETGDPRFSKIARQHADTTAKYLVRKDGSTGHIAEFDAESGKYIRLLGGQGY
                     NENSCWSRGNAWALYGFALSYRYTKNPYYLAIAEKIAVNFIQKIEKTGYIPLIDFAVK
                     DSNIDTSAGVCAACGLLELAGYVSSVRSKMYHEAAINILQKTEKHYANWNMDEDGIIG
                     GGAEAYHRELTYNVPLIYSDYFFIEGLLRLEQSELAIW"
     gene            complement(20097..20930)
                     /locus_tag="ACG8LA_001962"
     CDS             complement(20097..20930)
                     /locus_tag="ACG8LA_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFQ0204256.1"
                     /translation="MTKQKIQSRIFTYVIIVFGALIFLMPYLYMIVASTQSNQEILSG
                     GINFKFGDMLLKNWQAIMARYNYPLIIWNSIVIAVISTVLATASSTMAGYALAKYRFM
                     GNKLLFNTVMLSRMVPFFTTLIPLFYIMSRLGLSNTYAGVIIPSIASTTSVFMMRQYS
                     SQFPTALMEAARIDGANEWVIFTKIAVPILSPTIITSGLLIFMGSWNQYLFPLVMLSD
                     KDKYTVPLIIKNMTVSSTGEPINYGAIMLILATSVIPMVLIYVWAQSKFKENDIGAAN
                     K"
     gene            complement(20923..21840)
                     /locus_tag="ACG8LA_001963"
     CDS             complement(20923..21840)
                     /locus_tag="ACG8LA_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFQ0204257.1"
                     /translation="MIQSSLPSKTIKNSKKKATDTSHKKSAYGLVTPFVIFFIVTILI
                     PIIISFAFSFMKIGYSFEFVGFDNYLAIFRDPLFIKSYTNVLIIMAGSIPITMLLAIY
                     FAVLLNSAQLKGKGFFRTVYYIPTITSTVAVASVFMTFFNPTGLFNGFLNALGINGVQ
                     WLTNPFWIRISMIITMIWLSVGYNTILFLAGLQGISKEIYESAEIDGASKFRQFFLLT
                     IPMLKPIILMATVLATINGLGNFNIPNIFFGTSNGPENSALVVGVNLYKTSFEMVDFG
                     KASAIAWTMVFVSVILSAIQFKFGGDKND"
     gene            complement(22067..23191)
                     /locus_tag="ACG8LA_001964"
     CDS             complement(22067..23191)
                     /locus_tag="ACG8LA_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HFQ0204258.1"
                     /translation="MKKRYKLVIALLNITLLFSLSACGKTNEEVTANIADPMIKKATT
                     LEVYVANGKLTNYVENAAKIYNRKTGANIDLKIVNVASGTATVQMITPKLVTHEDMPD
                     IISMADTSAAGVLEKFQDAFYSADEYGFYDKYGDQFYDQKLNILRQQTSNETIIPWAS
                     DFTPALCYYQPKKFAEIGVDFEEISSWEEYIQVAKALKEKTGSFGIALPESGDQELFI
                     NMLAQQNQSLLDEEGNIRLNTKEAKHAAKLIKEMIDSDIVHFYGAQDAEKAFQESAMF
                     VAGGWYATNMSLNFPDASDKWRMAPLIPFSKENPGKGAVSGGSSFYVPKDAKNPQVAQ
                     QFLTFMLTDEECLANALELGVATSNSLAYQTEAAEKKFDY"
BASE COUNT         7332 a         4560 c         3804 g         7553 t
ORIGIN      
        1 catttattcc tcttctttct aataaatgtt aaaatgtagt caaataaagt tttcttagaa
       61 ctttattgtc gagtgtttcc tgtggtcgcc aaactgtcgg gaacactcct tttaattttt
      121 ttcaaagtat ttttatattt tctatacttc atcattattc aaacaaacac ttcctttttt
      181 ctatcaaaag cacgccacgc aactttttat acttcatatt ctttgataaa ccttgctaat
      241 tcttcttttc taataaattg acaatctccg attatgctta cttttaaacc tttctctctg
      301 ataaattttt ttaatgtact tctgctacag cttaaatact tacaagcttc ccccaatcta
      361 aaaacttctt tgcttagaga tgtttcaatt cgaacttgat ctactgcttc ttttgcaact
      421 cgatagaaat atcttcgcaa ttcttgatct aaatccgatg gaagaataac ttgaatctca
      481 gatttcattt tctttgcccc cactaatttg actacatgta ttcaaattca acttttcgtc
      541 acttttcatt aaaaaaaatt tgatcaattg tgatattttc aattcctttt tctttcacaa
      601 gatacttcaa aataatcatt tcttctggag aatagtttgt tttaccgctt tctttgtttc
      661 ttaccgcttg tactgaaatg ccatattttt cagcaagttc agattgtgat aatccacaaa
      721 actttctaaa atctttaggc ttcatgactc ctcactcctc cttcttttca acttttcgtc
      781 actaaaagaa taacatatat ttattcatac cgcaacgtaa aattcaactt ttatctactt
      841 tttcatttca ttatatgaga atgtagtgta aactgtagaa tagaatagat gaaggtggtg
      901 aaaccatttt gtttgataaa aacattaatt ctgaaattgg aaaacgaata caagaaatac
      961 gtgtttcttt agggtatact cttgaagaat ttggcgaaaa tctgacacct cccgcaagca
     1021 aaagcaatgt ttctagatgg gaaaaaggaa agaacatacc caacaaagcg cggctactaa
     1081 gtattgctaa acttggtggt gtttctactg aatatctact gacaggtaat tctcaaaaaa
     1141 ctaagaaata tatcaagtat ttattcaatg agattttttt tgacaacggt accttccata
     1201 acaaattcaa agatttcggt aaagacagag ataggcttgg tctatatgac ttatttttag
     1261 cagtatcgaa aacatatagt ctagataaat caccttcttt aaaagataac tttgtagaaa
     1321 tgattataga tgatgtatat aaaaaactct tgcaaactga taaatcagat gaccaactca
     1381 tcctgggttt catatatatt tgtcttgatg aaaaactttc aaacagacag aaaagtctta
     1441 aaagtatcaa ttatgaggta ttcaattatt taggtgttgc atttggttta attgatagcg
     1501 aaatcaaatc tacaaacgca ggtaacgatg aagatttatt aaattattta aaagaattaa
     1561 catcttttat tgatgaaata aaaacaacta cattcaacaa aaaaaaatat tttcaaaatc
     1621 aatatgatat agaagaataa agattacatt ttcctatcaa aagcacgcca cgcaactgat
     1681 aggaggaaaa acaatggcaa caattaaaca atatgaaaag aaagacggaa ccaaagcttg
     1741 gatgtttcaa acataccttg gaatcagccc gctaactggt aaagaagtcc gtactacacg
     1801 tagaaatttt aaaacaaaaa aagaagctca aatagagctt aatagactac ttgtagactt
     1861 tgaagagaat ggacttaaaa gggaaacgaa cgaaactttc caagaagtgt atgatctctg
     1921 gtatgaaagc tataaaacta ctgtaaaaga agtcactcaa ttaaaaattg agatcaagtt
     1981 taataaatgg attcttccaa aatatgggca gtttagaatt aaagaaatta ctacaaaaca
     2041 tgttcagaag atattgaatc agtgggctaa aacaacagat caatataaag tcctacattc
     2101 taccgtaagc cgtattttca aatacgcaat gactctaggg ctgatcacta aaaatccctg
     2161 tgagctcgta atcatgccca acagaaatgt tgaaaaaaag aaggatactg tcaaaattta
     2221 ttcacgagat caattagaaa ccttatttca atatttggaa tccaaaagaa gtacgtatag
     2281 ggcagagtac gataaaactt tactgcgctt tctatttttt agtggctgtc gaatcagtga
     2341 ggctttagcc ttagactggt cagatattga ctttgattca aacaccgtca ctataaacaa
     2401 aaccttaagc caaacaaaat atgggtacaa aatttcaagt ccaaaaacga gaaatagcta
     2461 tggttcccta tctttagaca ataaaaccat taattggcta aagaaatggc aaatcaatca
     2521 aaaaagatat atgttaaccc tcgggattac tgatccaaca atgatttttt gtggaatcta
     2581 caaagaaatc attactaaac acgctatcta ttctcgtatg atcacaatct gcaagaattc
     2641 tggtattcca tttctaggta accatgtaac cagacacact catgctagta tgctgttaga
     2701 gtcgggagtc tccatgaagg aagttcaaga acgccttaga cactcatcaa tcaaattaac
     2761 aatggatacc tatgctcatc taactaaaga aaccaaagaa aaaaccgttg aaaagcttgc
     2821 agagcaccta aatttctagc ggaacgtatt caatcccgta ttcaattcaa aacaaaaaaa
     2881 agctgaaccc ttatctacca agggttcagc tatcatttac agcttattct tcttcttccg
     2941 ccatgaatgt attgaatact tcttcaatca tgtcccattc tgcgtctgtt tcgatttgtt
     3001 ctaactcgcc ttctgttcca tcttcgtttt cgatgtatgc ataagcttgt aattctacat
     3061 cttcatcttc tgaaacacca gcaggatata aaagaacata gttacgtcca aattcttctt
     3121 gtccgtcaac tgttagtagg atttcatata atgtttcatt tccttggtca tccaccaatg
     3181 tgatgtgttc gtgtccttca tggtcgtggg aatggttatg ttctgtcata agattacctc
     3241 ttttctttta ttattaaaat aattgcttac ctgagccgtc taaataattt tgtaagatca
     3301 tcacagctgc taatttatcg atgacttttt ttcgtttggc tcttgaagta tttgcctgct
     3361 ctactagcat acgttctgcc tgaacagtgg ttaatcgttc atcttgataa tcaactggca
     3421 aggagaatag ttctttgatc ttttctccgt atgacatgga agcttctgcc cttggtccga
     3481 tggaattgtt catattttta ggtaatccaa ctacaaaccg gtctacttca tattgtgcta
     3541 ctaattcctt caaccgatca aagccaaact cttcttctgc ttcattgatc cgaatgatct
     3601 ctactccttg agctgtccag ccaaaggggt cactgatagc aacacctact gtcttagaac
     3661 cgacatccaa gcccattact ctcataaatt cactccatga tttgagaggt agtccttgac
     3721 aattacttcc atgatctcat cgcgttcgtg acggcgaatc aaatttcgag catcacgata
     3781 acgaggaatg taggccgggt ctccagaaag caagtagccg acaatctgat tgattggatt
     3841 gtagcctttt tcttccaaag cccgataaac aatcgctaat gtttcgctca cttctttttt
     3901 gcgactatcg tcaaaaccaa aacgtacggt ttcatctgta aaacccatga ttctacacct
     3961 ctttcccgca aggtaattcc agcttacctt ctacaacctt attttactcg aagaaaggga
     4021 aaactacaaa caaatattcc aaacttccga ataaattaag aaacactatt tgtatgtttt
     4081 tttccttttt tctgtagctt tatcaaaagt actcttttca taaagtatac gctatatttc
     4141 tttgaatgta tgtttttaca caattttttc ataatattca taaaaaattc gaatagctgc
     4201 tactaatttt ttgtttttgt tgcttgtcct gtctcataat tgatcgtgta gccatcttga
     4261 acattgtaga taaagacatt gaattcaatt tttttgtctt caatgctttc tgcttccaat
     4321 tgcactcccc tggctaccag ttcattcccc tcaaaatgag gagtgacacg gtagcgtaca
     4381 tgatgatttg tttctttgat atatgccgca atatcatttt cgtgagcaag catgtatgga
     4441 gcattcaacg aacgtgtccc tgtcatcaag tttttaatgt tgttattttg accagtcagc
     4501 tggaaaccaa ttaaatggct gcgattatat aaccattgcc cgtcacttaa tttcttttgt
     4561 ttccaacctg tcgggtcaat atacaaaggc tctctctttt cagtagggaa caaatctttt
     4621 ccaagcatag cattggcttg tcctactctg ttcaatttat caatatttga atagctttcc
     4681 catgttcctt tggaaaggct aagatcctct tttgtaaatt ccggctgatt cccattgatt
     4741 tctatttctt gatgttttcc atcatattct ggcacatccg ctacttgaga agcttgtggt
     4801 gtggaatcaa aaatagttgt aatctgctga aagatatctg aatctttttg tgtggtggaa
     4861 acaccgaatg cccctgcaat cacagcagcg acgatcccca cgatcgcctt ggttgttttt
     4921 ttgctcattt ctttactcct ttactaacag ctccctaaat cttaacatat gttcccctat
     4981 aaataaatac tagaaagaaa tagaaacagc aaaaaataaa acctgtttta agatggctta
     5041 aaaatacaaa aaagagacgg attcctcgtc tctaatcagt caccactcta tctgtaaggt
     5101 atttattatt attcaaaaat tttcttcata ctcaagacaa tacactgatt tcacaaccgc
     5161 ttggtaaacg gtgcgcaaaa gcttgcatct gcggtaataa gtccatccaa gttaaaaaca
     5221 taagaagttg tttttgcttg gctgttctta ttacttgttg cagagcagct ttttcacaac
     5281 ctattttaag cgggtgacgg gaatcgaacc cgcgacatca gcttgggaag ctgggatttt
     5341 accactaaac tacacccgca atacaaaaac agtatacgcc tcttttattc cttcctcaag
     5401 tttttttatt ctttacgctt ctggtatgtt ttgtagtaaa ataaaactaa tcaatcaatt
     5461 attggagaag atgctatgac gggaaaagaa ttagatctgt tgctggacac ttgtttactc
     5521 gctgggaaaa tcatgatgga aagcaatgcg gagatgtatc gggtagaaga tacgatgagt
     5581 cgaattgctt tagcttctgg aaatttccgt ttggtcagct atgtcactca aaccggtctc
     5641 tttattggtc ttgatcgtac ctcgaccatc cgaatggaac aaattaccaa ccgttcgatt
     5701 aatttagaaa aagtagtaaa agtaaatgat ctttcacgta aatatgttgc ttcagagcta
     5761 acattagaag aactttactg cgaactgcaa gcaatcgacc gagaccgttc tttctttcct
     5821 gtctggttgc aaatcgttag cgcggcagtg atcagtggaa caattatggt gttatttggc
     5881 ggaaagatga ccgatttacc tgtgacttta gtcattggag gattgggata cgcagcttat
     5941 ctatatagtt tgaaattttt tagaatcaaa tttttatcgg aatttttatc ttctttattg
     6001 attggcatag ccgctatcta cagcgtacgt tttggcttag gaagcaatca ggatctaatc
     6061 attatcggat gtgtgatgcc tttagttcct ggagttcaaa ttacgaacgc tatccgtgat
     6121 ttgctagctg gacattatgt ctcaggagtt tctcgcggaa cagaagcgat gatgactgct
     6181 acgatgatcg gttttgcgat tgcttttatt ttccagcttt tttattagga aaggaacaca
     6241 agtatgggga cgatatttat tcagttttct tttagttttt tagcgactgc ggcatttgcc
     6301 gttattacaa atgtacctag gcgttcattg atttgttgtg gtctttctgg tgcttttggc
     6361 tggatgatct actggatctg tgttcaaata ggcggatctg ctgcttttgg ttcattgctt
     6421 ggttctttag gagtagcatt catcagcgat cttttctcta aacgtttgaa aatgcccgta
     6481 acgattttca atattcccgg gatggttcct ctagtccctg gtggtttagc ttatcaagcg
     6541 gttcgaaatc tcgttactga atcctatcga gaagcggctc attatgcggt ccaagcaatt
     6601 atgattgctg gagcaatcgc tttaggtctt gtattatcag aagtctttaa ccataacatc
     6661 cgtaatttca aagtaaagcg tgacgcaatc atgatgaaac gaaaaaaacg gctttttaaa
     6721 taaacgaagt gtaacaaaga aaaggttgtg aaagagacgt tcagccttga gcgatgacaa
     6781 aatatctcac aaacattgcg acaagtaacc gcaggagcaa taagaagtaa ttatgagtat
     6841 taaaaaaagt tttgtaaaaa tagcttctca catttttaca taaaattgac ttaatactga
     6901 gaaactgact tttgaacacc ctctatctgt aaaaaagggg ctgcgacatg atttttgtca
     6961 cggcccctct tctttattca aattttttcc aaaacgttcg ttgataataa acgatccata
     7021 gagcggaaag tattagaact aaaccgatca caggaatatt cactaaccaa aatggataaa
     7081 acaaagccaa cattccgtat aagacgataa gaataatact gatgatcaat gaacccatca
     7141 tagttgcgac taaacccaaa cttcctgaac ctctgttaaa taattggtta atattggtcc
     7201 agttcagcag cagcaaccga taatctctag cgaaataacg tagtgacaat aagtagcagc
     7261 cgaataaaga accaaatagc aagctaggga taaaaaacaa aggcagctga aaagacagtc
     7321 cgcttaataa tgcgatccca ccagttaaaa aactctgcaa tatccatccg aatctgaact
     7381 tttcttttaa atattggttc atagagattg gcaaagaacg gataaacaga aaattttctt
     7441 gatccaaaga aataagattg ctgataaaag aagtctgatt aactgttaag aaagccaatg
     7501 cgatccctac caggaaaaca acaccgatta acttattatc taaatcagtt aattttattt
     7561 cgcctcctag ggcaaaagca agaataaaaa tgattggagt taacaaggaa gaagaaagaa
     7621 cttgcataat caaattaggt tcttttacta attgagcatt gtaactaaat aaaagctgat
     7681 gcacattttg gttcttttta tgggttcttt ttattttgaa ctcactgttt gaatcagtca
     7741 gttgctctgt aagctttggt actatcagct gttttacagc aaggaaaaat cccagagccg
     7801 tgatagctag tattccccaa cccaataaac cttgttgaga aagtggctga ctggcagcat
     7861 catagaatgg caataatatc gaaatcggat gccgatctgt taactcattt tcaatagtcc
     7921 ccgtttgatg attcatccac atgattccag caaatgcgat cagcatcgag ctgccaagca
     7981 agatactaga aactgttttt ctatgttttt taaacactgc tgttcgagcc aaaccaaaaa
     8041 caatcaaact agccagacaa aaaagaataa tcaaaaatag agaaaacaaa aggattgaga
     8101 taatgatagt aagcaaaatc cctagatcag ctcgccatcc ggttaaaata aacatgacta
     8161 gaagcggaaa aacaaaagga atgatggtca aagcaactac caaaatcttt gctgaaaaaa
     8221 cctgttcttg tccaaaaggc agaggcaaaa atacttgcag gtcatttcct tcaaaaaaga
     8281 tattataaat gactgatata ctttgagtta aacctaacat accaaaaagt gccacgtaat
     8341 aagtaaagaa acctggcaat ttaacaaagt tcatagcaaa catagcaaat ccgtaaatca
     8401 gtaaaaaaat cagccctgaa aaaagatttt gagacaaaag atagatagtt aatcgctttc
     8461 ccttttttcc tttctctctt gctttattcg tgagctgtgg attaacatat aaaagattaa
     8521 ctcgaattaa ttctaataat tgtcgcttat acatacggtc catctcctgt cgcttgcctt
     8581 ccagccattt tcaaataaat cttttctagc gtttcatcag gtgagccatt caataattca
     8641 ctaactgccc cctgataaat caattcacct ttcttcaaaa tagccagttt atcgcataac
     8701 tgttgtgcgg tatccaatac atgtgtagaa aaaatgactg tttttccttt tgcggcatga
     8761 gccttcatca tttctttcaa atcaaatgct gcttgaggat caagtccttg caaaggttca
     8821 tccaataccc aaatatctgg atctggcagc aacgtgccga tcaaaatcgt tttttgacgc
     8881 attccatgtg aaaaacttgc gattgtttca ttttgatgac tatacatatc aaaaagcgct
     8941 gtcaattctg ctaaacgctt ttcttttttt tgtgtgtcta attcataggc agctgaaatc
     9001 aagtcccaat attctccagc cgtcaattgt aaaaaaatat ctggggaatc aggcacataa
     9061 ccgatttttt gtttgatact caatcgattt tccgtcaatt tcattccatc tactaaaatc
     9121 gttcccgatg atggttcaat aatactaact aaacttttaa tcgtagttga ttttccggca
     9181 ccattatgtc ctaaaaatcc aaaaatttcc ccttgtctta tcgagagaga caagtctttt
     9241 aatgcttgtt ttttcccgta acttttactt acattgatga attcaatcat ttctgtactc
     9301 cttttgtttg ttattacttt ttattgtacc cttcgttatt ggtggagtaa atgtcaaaaa
     9361 gagtgcataa caaaaaagga tagaaacgac taggctgcta cttgggttgt tctcttctac
     9421 aggaaaacac tcttctaaca ggtaagatat gagtctttgt tttctttaaa atgattcatt
     9481 ttctatcttt tcttgcataa aattctttag tttatcaata cttctctttc ccatctctag
     9541 ttgttctcca tttgcaaatg ttactatttc gtttactctg ctaatagatg taatgttttc
     9601 agtattaatg atataagctt ttaaatcttt acataaatac tcatattcga gtgatttttt
     9661 atatttttta attgtgccgt ttacgagaat ctcttcatct ttcaatacta ggcctatttt
     9721 atttttataa cctggcatgc tcattagata aaggatttca tcgtaatgga tatagtgatc
     9781 gctattacca taacggacag ttgtccacct ttttttcgta gcatgttgaa caggatagtt
     9841 ttctttttct ttcaataagt aactttggat gcttttttta tttttttcat aagtgaattc
     9901 ttttatcaaa taaccactag gcgtaatctt tcgattaata acagttattg ctttattcgg
     9961 atgagacgtt agataaacaa ttttacactt ttcattcttt tctctaagca tttcgcctag
    10021 ttcgataccg ctataatagg cgttcaaatc gatgtctagg aaaaaaatat ctgaggaata
    10081 gatttcatta tttttaatga attcaacaaa ttgtataacg ttcaatccct gaacgatctc
    10141 aaatttccaa ggacttaata aaattctgga ttcttccaaa atttctacta gcattttttc
    10201 aaaaaccaaa ctatcatcca aaataaatat acgcgttacc ataaaaagta cctccactcg
    10261 atattttact atcaaaatca tttcatacaa cttttcaaca tacatgttag gaataaattg
    10321 taattctctt cacaatcttt tccaacacct ttgaaaccga tatcaaatac tttcaggatg
    10381 ctgcttctaa aataaatatc aaacaaatga atacatcatg caaaaaaagc cagacaaccg
    10441 acgtccttgc gtgtcagctg tctgagctat gtttatttat tttgttcttt taaaaagaac
    10501 gatacacata ctgatttttc ggagcagaga ctttctcagc gtttgtaaca actacagatg
    10561 ggatttcacg cttgaatggt tgataatagt ctgattggat ggttccttct attttatacc
    10621 attcatcatt tttaaccgtt actccttccg gcatatgcgt caacaaacca aagactcctg
    10681 aatctgccac acaatggata atgccgaatc ggaacaagaa gatatctgta ttgctatcgt
    10741 tcggtgtttg gtaaacaaat ccttcatagc tgattttttt gccaatgaat tcgctagggt
    10801 aattataaat tagctccata acttctaaat agttttcatc tgtgatcttg atagtttgct
    10861 tatccccata cttttctttc aactcattca tttggtctaa gtagtctgat ttgttgaaat
    10921 aaatactggt atccggcttt aagtattgtg tctgcatctc cggatcccct actgattctt
    10981 tacttactgg gaaattaaat cctttggctt ctacgatcgt agtgtcgaga ctaactgttg
    11041 gaaacaacgt ccccacgatt actggcaaag ctagcagtac ataagcgatt ccacgttgat
    11101 aaggttttga caacccatgg tcatgatcgt gctcgtgtgc cttttcttct gcttttccgt
    11161 ttttgaccca caaatacagc tgaactaaag ccaaaagagc agataaaatc attgaaagaa
    11221 tagctaagta gcgataatgg acattgatat attgatcgag tttgccagaa acttgcaagt
    11281 acatcatcaa ttcgaaatac ccagataaaa tcaaaaaccg cagcatattt tccctcctaa
    11341 ataaataatg tgaatccaat aacgctaagg gcaatcagtc cgatcagcga taaaataaag
    11401 cgtcctgtaa aatatcgttt catcatcagt agatttttga tatcgaccat tgggccaaag
    11461 accaaaaagg cagctacagg tgctgtgccg aacagactta acaaagaaga tcctataaac
    11521 gcatctgctt ctgagcaaag agacatcgta aaggccaata acagcatgat gataatggct
    11581 aaaatctttg ttgagccgag cgttagcata attctagttg gtaaataagt ctgcatcgca
    11641 gctgcgatta atccgccaat gatcaaataa cgacctgtat caaaaaattc gtcgattgaa
    11701 tgtgtcaaca catgcccagt ttgatggatc agctgatttt ttggttcatt cttctcactt
    11761 tgttcttctt catggacatg atgatggtga ttttctgcta ctttagacgt gattttttct
    11821 ttcaatacag cgtctttttg aaaataggca agccagacac caatcacaag ggcaacaaaa
    11881 aagctgccta tcacccgcca gcttgccatc tgccaagaat tgccaaatgc gataaaagtg
    11941 gaaaaaatca cgattggatt gatgatcgga gcagtcagca taaaagcaaa cgctgtgtga
    12001 actggtacgc cttttttaac aaattgatga acgatcggta cgatgccgca ttcacatgaa
    12061 ggaaagaaaa atcctaagat cgaaccagta aaaatagaga agatacgatt ttcaggaagc
    12121 catctcttca cacgttctgg ggtcaaaaat acttgtaagg cgcctgagat aagacagcct
    12181 aataatacga aaggtaatgc ttcaataacg atcgataaga aaatcgtact catctgcaaa
    12241 accgaatttg gaataaaaga aaacatgagt ttcctccttt ttatttctag ttcattcgct
    12301 ttgcaaatat acgcttttat tcaaaaaaaa caagttgctc tgtaaatttt tacacaactc
    12361 ttatttttta ccaaagcact tcaattgact ttttctgtta ttcccattaa attaaggtct
    12421 catacatatc acttctatca taaaagggag aataaaaatg aaacaaacca ctaacttgac
    12481 tgaagttcaa gacatactgc aacagtcatc cgttgccgtc atttatcttt cgatgcctaa
    12541 ttgcagtgtt tgtcacgctg ttcgtccacg actagaggaa cttctcacac attatgatat
    12601 tccggcactt catttggatg catttgaaac accagaagta gctagtaaat ttgaagtgct
    12661 gactgcgcca gttgtcctga tttttcatca aggaaaagaa gtctttcggc aagcacggtt
    12721 catcgacttt aaaaaaatcc gttatctact agatgaactg acagcagaag atgattccct
    12781 ttcttatgaa gaaatcttcc gaacaaaata atcgttgtcc aaacagaaaa aagcgattga
    12841 acaagtgaaa gttttgcctt catttgttca atcgcttttt atttttattc tgctgtattt
    12901 tcggaatgcg catttgcgtc agaatgcaag aaatagatca aggtttgcaa ttcattcgtc
    12961 aaatcaacat tttggatcaa tacatctgac ggagcattca atcgagcagc ggtaaagttc
    13021 aagattcctt tgattcctgc ttccgttaac tgattgacta cttcttgtgc tctttcagcg
    13081 ggtatcgtta aaattgctac ttcgatttgt tggatcttga tttgttctga catatcttcc
    13141 attggataaa cggggatacc gtctacgatg cgcccaacga tttcctcatt cacatcaaaa
    13201 gcacaactga tacgtatgct attactttga tggaatttgt attttagtaa agcacttccc
    13261 aagttcccta caccgatcag cgcaacattt gtcaattgat cgtcgtttaa tgtctttgca
    13321 aaaaagtgca taagatcttc tacatcataa ccatacccac gttttcctaa ttcgccaaaa
    13381 taagaaaaat ctcgacggat cgttgcacta tctacttgaa cggcttcact taattcagtt
    13441 gaagacactt ttttctttcc agcattattt aaaatcctta aatagcgata atacaaaggc
    13501 agtcttttag ctgtcgcctt tggaataata tgatctttca cgaaatgacc tccacgtatt
    13561 gtctaattac atctttgatt tctccatcat agcagtattt ataggaaaaa atcaattcca
    13621 ttgctcagat attgtgaaat tttattcttt attcatttat ttatcatttc tgcaaatctc
    13681 gcagtataat ggaatttatg gtagactact aattgaaaaa tagtttttta tttgaggaga
    13741 attcacaaag tagaaaagag gattccatga tattattaca agccaatcag attgctcgcc
    13801 attttggtgc agaagtctta tttgaaaaca tacatttaga aatcagtaca ggcgctcgtg
    13861 tcgctttagt tggcagaaat ggcgctggaa aatcgacttt attaaagatc attgctggaa
    13921 ttgaagcacc tgatgaagga aagatcgcta aaaataaaac agcgactctc ggatacctcg
    13981 ctcaggacac aggacttgat tccaatgaaa cagtttggaa cgagatgctg aaagcttttg
    14041 aacaagttag acaaatggaa gagcggatgc gcgagctaga gattttcatt agcgaaggta
    14101 cgccagacac acctgcttat agttcttatt taaaagaata cgaccggctg caacacgatt
    14161 tttcagatcg aaacggctat ggttatgaaa atgaaattcg ttccgtattg catgggttta
    14221 aattcgattc ttcattttat gatcagaaaa tcgatacttt atcaggcgga cagcgcacac
    14281 gtttagcttt agctcgcatg cttttgcaac accctgacat tttgattcta gatgaaccaa
    14341 cgaaccattt agatatcgag acactttcct ggcttgagaa ttatctgcaa agctatactg
    14401 gtgcattatt gattgtttcc catgaccgtt attttttaga taaagtagtc aatgaagtct
    14461 atgaattaag cagaagaaaa atgcgccatt acaaaggtaa ctattcgaaa tatctagatt
    14521 tgaaagcaga acagttagca agtgaatgga aggcttatga aaagcagcaa acagaaatcc
    14581 ataaattaga agacttcgtt gctcggaacc ttgttcgcgc ctctaccaca aaacgagcgc
    14641 aaagccgcag aaagacatta gaaaaaatgg accggctgga tcgtcctcaa ggggatgaaa
    14701 aacaagcaaa ctttctattc agtatagaaa agccttctgg aaatgtagtc ttgcaaatcg
    14761 aagatgccgc tatcggatat gataatgtca ccttatctga accaatcaat ctagatatcc
    14821 gtcgtcaaga agcgattgct ctagtaggtc cgaatggtat cgggaaatcg acgttgctga
    14881 aatcaatcat tcaccagatc ccttttatcc gtggaaaaga aacgctaggg acaaatgtca
    14941 ccatcggcta ttacgatcaa ggtcaagctg atctgcatac aaacaagacg atcctagcag
    15001 aattgtggga tgagcatcct accactccag aaaaagagat ccgaagtgct ttaggtgctt
    15061 tcttattttc tggcgaagat gtagaaaaac caatccctct gctaagtggc ggtgaaaaag
    15121 cacgggttgc tttagccaag ttagcgatga acaaagaaaa ttttttgatt ttggatgaac
    15181 caacaaacca tttagatatt gacaacaaag aagtattaga aaatgcattg atcgattatg
    15241 acggcacact gctttttgtt tcccatgacc gatatttcat caatcggatc gcgacaaaag
    15301 tcgtcgaact ctctgaaaat ggcagcaaag tctatctagg agactatgat tattatttag
    15361 agaaaaagca ggaagaagaa gaaatcgccg aattgttggc acaagatgag ccagaatctg
    15421 ctcctgctcc cacgaacaaa tctgattatt accaaagcaa agaacagcaa aagcttatcc
    15481 gtagccttca acgaaaaatt actcaggttg aagaagaaat ggcgcggatc gatgaatgga
    15541 tcgatcagtt ggaacaagaa atggtcgcgc cagaaaacct ggaagatcac gtaaaactca
    15601 atgagctgaa ccaagattta gaagctgcta gacaagatca agaaacaaaa ttgacggaat
    15661 gggaagaact aagcttggaa ttagaagaat atgaaaatta acgaaaaaac caaaacagaa
    15721 accattcatg ctgttttggt ttttcttttt ttattttatc aaacaaaaat tccatattta
    15781 cctttttcac caataagaag accaattact agtcattctc actaaagctt ctaaataata
    15841 gtaatcaccc caaatacaag gtgtatttac cccattattt ttgggcttat tataaacaga
    15901 ctgtgttaaa aagccatctt cttcttccgt tgtagcatat ctttctttca attgtcgcat
    15961 aattttccaa acagcagact ggtataagtt cttttctgtt ttgtctaata gacctgattc
    16021 tattaattct aataatccac aaaccatgat caccatacta gatgtatctt tttcttctct
    16081 gctagaatca tcaaagatca aatcccaata acaaatggta tcttctggca accgattcat
    16141 aaaataattg gctaatattt tgcttaaatc aaaatatttt tgttctttca aataacgata
    16201 acttaatgca aaaccgtaaa tcccccatgc ttggcctcta gcccaacagg aattatcact
    16261 ataaccttga tgcgtacttc catatcttgg ttttccatct ttgacatcca tataaaatgt
    16321 atgataagtt gaaccatctt ctcttactaa ataatctgct gcattttgaa tatgagcctg
    16381 agcagctttt ttatattttt gatttccagt ttcttcactc gcccaataca ataatggaag
    16441 attcatgcaa caatccatga tcattctacc ttgttgtgaa ggatcactag gatctcccca
    16501 agcttgtata actcctgcct tctcccaaaa acgctgaagt aatgtttctg cagcatcaat
    16561 tgaagcttcc ttcatttttc gatttcccgt tattttataa tctgctacgg ttgataaaga
    16621 atacaaaaaa ccaagatcgt gatgattagt gataatttga cagtcaatcc tgtggataaa
    16681 atctatatct gctttttcag ctgtttgttg aaataaagga tcacccgtct tctcaaataa
    16741 caaccaatta attcctgtcc aaaatccttc tgtccaacca atattgtctc ttaatggata
    16801 acgtcctttt ataggacact cgcttgggaa ttgatactga ctgttactga tacgtttgat
    16861 taacctctcc gtgtgtctgc gacaacgctc gatctcatta ttccattctt tttccattaa
    16921 ttctttataa cattcattta tccatttttc tggatgtatt atctcttcaa acatcacttt
    16981 atcaagcatt tccccaccag cctttagcat aattttagtc tttttttatt gtttttattt
    17041 tggatagtta gcccggttgt cccatcaaaa tcaattttgg gacgattgtt ccatacttct
    17101 aaactataat cccgatcttg atgagcaacc actcctgttc cgagccaatg ggttcctttt
    17161 ccaaatgtac cctctaatcc aggaataaaa gtgttttccc atgtcatcaa gtttgtattg
    17221 ggcaaaccca taatagctgt ggattttcgt ttaatagtat cgtcacttaa acagataata
    17281 cctgaaaagc cagcttcact caccctatag ttttccttgt cttcttctat gattattcct
    17341 tctttctcag gagaacattc aatagcaaac cctgtctcat atagaacata ttctgtatct
    17401 aattctactt tgtgtacgcg aatctgccag ccttcaaaag gaataagcca agttctgatt
    17461 tttgcctgta aagtaggttc ccatgtagag gcaagtacct ctttcttaca tacaatgtct
    17521 cgtacattat ttcgaacgat gaactgtcca taggttttga tgctctcatt cttaaaactg
    17581 gtcgtgatat atgtgtccgc tcgctgaatc cctagcattg aatccattgc catttctgct
    17641 ttcaattgat tcgctcgcgg tatcgaaaaa ccaaattgac tagaataagc aaattttaaa
    17701 tatttttcat tggtcaatgt atggaaattt ggccctaatt gtcccgcatt caaaaaaaat
    17761 gtatgtccat tatcatgttg tatgagcaaa ttggcttctg aaagaagttt agttccttca
    17821 cgaataggca taggcatttc tttagccgtc caatactcat ggtcttcagg tagcgccaac
    17881 aataaaaaaa tcttattcag ccataatgga gataacgtac tattataggg ttcagtcaat
    17941 gtcaattgag ggtaggtata accaatattc aggatacctt tttcatcaaa tatttctttt
    18001 tgcatccacc atcttatatt ccgattgact aaccccttga tttcacctaa tttaaaaggc
    18061 aaaagatcgg cccacaacat agctgaccaa aagcttgaaa ctgcaaaacg ataaatcatg
    18121 cttcgaccaa aaggcacatt tgcaccatct tccgcaaaaa aatgaatata gtctctagaa
    18181 aaatcaatag ctcggttctt atatatctgg ctaatgggct tttctggttc tagtacgcta
    18241 taaatcaaac cataataatg aaatgcaaaa ggattataat aatcttggcg acctcttgaa
    18301 ctgtctcgat accagccatt ttgaagataa caattttcta tattatcaaa tgcttctttc
    18361 agtgctgatt ctttaactgg ataaccaaat ttttggataa ttgttccgac aattatctta
    18421 aaaaattgcc aattaccatc tgcacattca tattcaaaaa tttgcgagaa ccaatgaata
    18481 atctggcttt tttctcctgt atctaatttt ttccataata attgttcatg atgatataac
    18541 gctaataaca ttgcgggcat ttctaccata cgctggtctc tttcatgtat ttctccccaa
    18601 taatcgggat gggaaggatc tgttccagct tttattcctg atagaattaa tttcaaccat
    18661 cgttcatcta attggtcaat tgcgggcccc gctccccata aaacccgaga gaatccttcc
    18721 attcctgcaa ttttatttcc atatcctacc ccttgatgta tataatcaat ttgtgcgcca
    18781 cttgctcgat aaaacggctg gagtggttga tttatctttt taaataagtc aaagtaatcc
    18841 tgtctggtcc ttaatagtgg tactggatgt ttcattgtat tttctcctct ttttactacc
    18901 aaatagctaa ttccgactgt tctaatcgaa gtaagccttc aataaaaaaa taatcagaat
    18961 agatcagtgg cacattataa gtcagttctc tatggtatgc ttctgctccg cctccaatga
    19021 tcccatcttc atccatattc caatttgcat agtgcttttc tgtcttttgg agtatattga
    19081 tagcagcttc atgatacatt tttgatcgta cagaggaaac atatcctgct aattccagaa
    19141 gaccgcatgc agcgcatact ccagcactgg tatcaatatt cgaatctttt acagcaaaat
    19201 caatgagagg aatataacca gttttttcga ttttctgaat aaaatttact gctatctttt
    19261 ctgctatagc tagatagtac ggattttttg tgtaacgata acttaacgcg aatccatata
    19321 aagcccatgc atttcctctg ctccaacaag aattctcatt gtatccttgc ccgccaagta
    19381 accgaatata tttccctgat tctgcatcaa attctgcgat atgcccggtt gatccatctt
    19441 tcctcactag atacttagct gttgtatctg catgctgccg agcaatttta gagaacctcg
    19501 gatcaccagt ttccctcgaa gcccaataca gtaatggtaa attcatcata ctatcaataa
    19561 tcatccaacc aggtttatgg tcattccatg ctactaaata gttccctgaa atattatagc
    19621 gtccagcaag taccgtagct gcatgtaacc ctagttgtcg actatgtttg ttttgagact
    19681 gttgataatg tgcaatagcc gatggtaaga ataaaaaacc tacatcatga tgaacgtctg
    19741 aaaaatggta cagggcagat tctaataatt gttcttgttg tattgctgcc tctttgaact
    19801 tttctcgttt tgtcttgtga aagagctgcc ataaaatacc actccaaaaa ccattggtcc
    19861 accagtcgat tcctctgtcc tttattacgt ctgtatattt tccgttgtaa gaaatatatg
    19921 gaattttatt ccccattctg tctaattccg catctatctt ttcagaagct acattcaaaa
    19981 tttttcttga ccattccttc gtctgttcat tcatggatat cccgccattc ttttaatttt
    20041 tatgaatgtg gagttgctcc tagaacgaac tagatggtta acattcgtta ttttttttac
    20101 ttatttgcag ctccaatgtc attctcctta aatttagact gcgcccacac ataaatcaag
    20161 accattggga tcactgaagt tgctaaaatt agcataattg cgccataatt aattggctca
    20221 cctgtactag aaaccgtcat atttttgata attaagggaa ccgtatattt atctttatct
    20281 gaaagcatga ctaatggaaa tagatattga ttccaacttc ccataaagat aagtaaacca
    20341 ctagtaataa tcgtaggtga taaaatcggt acagcgattt tcgtaaaaat cacccactca
    20401 ttggcaccat cgattctggc agcctccatc agtgctgtag gaaattgact gctatattgt
    20461 cgcatcataa acactgaagt tgtactggca atcgaaggga tgatcacacc tgcataagta
    20521 ttcgataatc ctaaacgact cataatgtaa aataaaggaa tcaatgtggt aaaaaaaggc
    20581 accatcctag atagcataac tgtattgaac aacagtttat tccccataaa acgatacttt
    20641 gctaatgcat aacccgccat tgtagaactg gctgtagcta aaactgtact gattacagca
    20701 ataacaatcg aattccaaat aatcaaggga taattatatc tcgccatgat ggcttgccag
    20761 ttttttaata gcatatcccc aaacttgaaa ttgattccgc cacttaaaat ttcttgatta
    20821 ctttgcgttg aagctacaat catatataaa tatggcatca aaaatattaa ggcaccaaac
    20881 acaataatga cgtacgtaaa aattctgctt tgtatctttt gtttagtcat ttttatcacc
    20941 tccgaattta aattgaatag ccgataatat aacagataca aacaccatcg tccaggcaat
    21001 agcagaggct tttccaaaat caaccatttc aaaacttgtt ttatataaat tgactcctac
    21061 gaccaaagct gaattttctg gtccattgga agtcccaaag aatatatttg ggatattgaa
    21121 attacccaag ccattgatag tggctaaaac tgtggccatt aaaatgattg gctttagcat
    21181 ggggatcgtt aataaaaaga attgccgaaa tttcgatgct ccatctattt cagcactttc
    21241 gtatatctct ttagaaatcc cttgaagacc agctaaaaat aaaatagtgt tatatcctac
    21301 actaagccaa atcatcgtga tgatcattga tattcgtatc caaaaaggat ttgttaacca
    21361 ctgtacaccg ttaattccta gcgcattcaa aaatccattg aataacccag tcggattgaa
    21421 aaaagtcatg aatacggaag ctacagccac cgttgatgta atggttggaa tataatagac
    21481 agttctaaaa aatccttttc cttttaactg tgctgaattc aataaaacag caaagtaaat
    21541 agctaatagc atcgttattg gaattgatcc tgccatgata atcaaaacat tcgtgtaaga
    21601 tttaataaac aatggatctc ggaagatagc tagataattg tcaaatccaa caaattcaaa
    21661 tgagtagcca attttcataa aactaaaagc aaacgagata atgatgggaa tcaaaatcgt
    21721 cacaataaag aaaataacaa aaggtgtgac caatccataa gcactttttt tatgagacgt
    21781 atctgttgct tttttcttgc tgttctttat tgtcttgctt ggtaacgaag attgtatcat
    21841 cgttaagtcc tcctaatatt ttttaatcac cagttaattt tacgccgtac ttatgagcaa
    21901 aattttctgc ttcttttaga tatgaatttt caaaatcacc tgtttgccaa tagttatatg
    21961 cagcggtagt caaataagac gtagcatctg aataagtggc tggtaaaaca gtatttgatg
    22021 tattttcatt gattttattc aatagttcat agtatttttg tcctccttag tagtcaaact
    22081 ttttctcagc tgcttctgtt tgataggcca atgagttaga tgtagccacg cccagctcca
    22141 gtgcgttggc taagcattct tcatctgtca gcataaatgt aagaaattgt tgtgccactt
    22201 gtggattttt ggcatcttta gggacataaa aacttgatcc tcctgatact gcaccttttc
    22261 ctggattttc ttttgaaaaa ggaatcagtg gagccatgcg ccatttgtca gatgcatcag
    22321 gaaaattcaa agacatattc gtagcatacc agccgccagc aacaaacatt gcagattctt
    22381 gaaatgcttt ctcagcatct tgtgcaccgt agaaatgtac aatatctgag tcgatcattt
    22441 ctttgattaa ctttgcagca tgtttcgctt ctttagtatt cagacggata tttccttctt
    22501 catcaagcaa agattgattc tgctgggcta gcatgttgat aaacaattct tggtccccag
    22561 attctggcaa ggcaattcca aaactaccag ttttttcttt taatgctttt gccacctgga
    22621 tatattcttc ccaagaactg atttcttcaa aatctacacc tatttcagca aatttttttg
    22681 gttgataata acaaagtgct ggggtaaaat cactagccca aggaataatc gtttcattac
    22741 tcgtttgttg acgcaaaata ttcaattttt gatcataaaa ctgatcgcca tatttgtcat
    22801 aaaatccata ttcatcagca ctataaaaag catcttgaaa tttttccagc acacctgctg
    22861 ctgaagtgtc tgccatggag ataatatccg gcatatcttc gtgtgttacc aattttgggg
    22921 tgatcatttg tactgttgct gttcccgaag ctacattcac aatttttaag tcaatatttg
    22981 ctccagtttt gcggttatag atttttgcag cattttcaac atagtttgtc agtttgccgt
    23041 ttgcgacata tacttctaat gtagtggctt tttttatcat tggatctgcg atgtttgctg
    23101 ttacttcttc gttagttttt ccacatgcac ttaagctgaa taatagggta atgtttagca
    23161 aagctatcac caatttgtat ctttttttca tgtctatccc ttctttcttt tcaagttctt
    23221 atataaaacg ctttcactta tgtatatta
//
LOCUS       DAZKKZ010000048        22637 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.049, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000048 DAZKKZ010000000
VERSION     DAZKKZ010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22637)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22637)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22637
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.049"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(226..1113)
                     /locus_tag="ACG8LA_001965"
     CDS             complement(226..1113)
                     /locus_tag="ACG8LA_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFQ0204259.1"
                     /translation="MKNMVEKETIERPNVKKQALELRSTIGSVLKYTALSILSFISIF
                     PFVWMVLGMTNTPVDITSGKIKIGSNLIINFQNLFSNELNFTRSLWNSAMIALVTTVF
                     ALLISSMAGYGFEIYQSKRKDLIFNILLLSMMVPFAALMIPLYRMFSQLNGTVLGINS
                     FLVVILPSVSTAFLIFFFRQNVKSFPKDLVEAARLDGLKELSIFFRVYMPTAKNTYAA
                     AAIITFMSSWNNYLWPLVALQSPDKRTVPLVLSAMGASYTPDYGMIMAGLVIATLPTA
                     IVFFVLQKQFVQGMIGSVK"
     gene            complement(1110..1979)
                     /locus_tag="ACG8LA_001966"
     CDS             complement(1110..1979)
                     /locus_tag="ACG8LA_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFQ0204260.1"
                     /translation="MKQKDLFKNGHAFLILPVILISIMVFIPMVLALITSFQSGPPVN
                     MTFNGLGNYQRMLTDATFKKAFFNTFLYLLVQVPIMLFLALFISNLLNDKKLKYKGLF
                     RTAIFLPCITSMVSYSLIMKSLFSQSGLVNNLLLGIGMIDTPIGWLTHPIWARVLIIL
                     SITWRWTGYNMIFFLSGMQNIDSEIYEAASIDGASKWQQFIKVTIPNLKPIILFTSIT
                     STIGTLQLFDEVQNITGGGPANATTTLSQYIYNLSYKFTPNFGYAAAVSFVIVSFIVI
                     LSIIQTKVGGESR"
     gene            complement(2116..3402)
                     /locus_tag="ACG8LA_001967"
     CDS             complement(2116..3402)
                     /locus_tag="ACG8LA_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFQ0204261.1"
                     /translation="MNIRKLIAGVVCLAAASGFLTGCGSASSTADKEEKVTVWAWDET
                     FNIKAVNEAKKVYENEETEIEVVTMSQDDIVQKLNTALASGNTEGLPNIVLIEDYRIQ
                     GYLTSYPDAFANLSAIVKEDHFAPYKFAVNKVGDKIYGVPFDSGVTANFYRTDLMAEA
                     GYTEEDMENLKWDEYIQVARDVKEKTGKKIAEVNPSDLGRVRMIMQQAGEWYTSEDGE
                     TVTIQDNASLKYGLELFATLLKEDLVEQTSDWNAGVTAIQSGAVASSPTGAWYSSTIQ
                     GAENQSGKWKIAPIPALPENLQKAQASNLGGAGWYVIKGVAGEDSAKDFLEATFASNE
                     ELMGTLAKEIGLVSTMLSANEQEAYQEASEFYSGQKIFDDFSTWTSEIPEVNYGHETY
                     AIEAVVAEALHRIINGEETDKVLADTQKQVEAQLAN"
     gene            3675..4253
                     /locus_tag="ACG8LA_001968"
     CDS             3675..4253
                     /locus_tag="ACG8LA_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFQ0204262.1"
                     /translation="MPIRVILIDDEQTILDGMKQLINWSEHGFQLIGTFSSPLKALDF
                     SLVHAIDIVVTDVMMPELNGIELSRLLKQQQPETQILILSSYDEFDMVKDSFKEGVAD
                     YLLKPRLSPDFFLNSLTAVSQKIKKKPNKSPITNRYEQICENLSQQIAGQTRPLLDPL
                     LFEHTLFFCYIPKNGHSVQNKALNKNSRSPIH"
     gene            4253..5182
                     /locus_tag="ACG8LA_001969"
     CDS             4253..5182
                     /locus_tag="ACG8LA_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0204263.1"
                     /translation="MDSDDSFTIYPVSTFSEESGYVINTDSKDTLRKFVQKFRQEVFP
                     GDFFVVSDSFAIQDINEIFQEIRNCTKGQRFYHKGKNLAYQHELLPLLTNHEQQASSY
                     LTKIVHKDYALAVKELENFFTTILEQPIDPAYLKHEAINRFYALLNALADEHVGNEEL
                     SLLKIALPSLLADAEYFEDFSILVKETLEKLTHFSANAKKDNFDILTLIYEFVQENYE
                     KEINLQLLSEKYHFSYSYLSAIFTEKFGINFSKYLKKVRISKAKLFLTETRLTLTEIC
                     EKVGYTELGYFSRVFKEETGMTPSQYRKGTFVK"
     gene            5179..6915
                     /locus_tag="ACG8LA_001970"
     CDS             5179..6915
                     /locus_tag="ACG8LA_001970"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFQ0204264.1"
                     /translation="MRKKIKEHELFAKLLFILFIGLFLQAIVISLFIYHRSRDAYIQL
                     FNQSNDVVLKKIQSEFESLNDTIENTLAAFDSNPAVKSYFSNDPAQHMEQLQQLRTIQ
                     KMNDSLSKIHPMIDYDVLIFGENGRTFVGNDMLTAVSADSFFQSAIAQRVNERAADTQ
                     MLFAHHGLTLRDKKAPSVFFVKKLKNTLNHVYGYAVLSISSKQLANLFQSVVNPEISK
                     ISFMNEEQTIIASNEENTIGSRSMIFKKLTVGETTISNGQQLTRLPLYRQDCTLLSQV
                     DLHSLSNQMGVIFPIILYNIVTLAFAGSLVFMYLDRHTKSIYRLIDSLKRLEEDGLKA
                     TVPVQGSHEVQLLGNTINQLLSNAQHHYEQTIQDEKKKRSLEIQTMQAQIQPHFIYNT
                     LTSLKFLIWQKKTDEAVQGIDSFITLLRSTIGKKEEVIPVKEEIKSVQSYIDLLSMRY
                     GERISAKIMIPDELQSLSMPNMILQPIIENAYLHAFHNKTQGFITVYGKTKNQLLLFE
                     VIDNGDGFDTENTKQKNDHFSGIGISHVDERIRLMYGDAYGLTIQSVIGTGTTVTICL
                     PLLPKNQSEYQK"
     gene            complement(6978..7814)
                     /gene="pheA"
                     /locus_tag="ACG8LA_001971"
     CDS             complement(6978..7814)
                     /gene="pheA"
                     /locus_tag="ACG8LA_001971"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004664 - prephenate dehydratase activity
                     [Evidence IEA];
                     GO_process: GO:0009094 - L-phenylalanine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HFQ0204265.1"
                     /translation="MNVSYLGPESSFTYQAACQLFPTEQLTAYASIPVCLRALFRKQV
                     DLAVVPVENSLEGAVHHTIDLLSKHPEVEVKSEIVLPIKQQLLGNPATKITKILSHPQ
                     ALAQSQQFLETHYPNVPLVATESTTAAAMYVAEHPKEDAAAIASLETAQHVGLEILAE
                     NIQDNELNQTRFWIVGDRKMTSQQSAPVKMSVILTLPANRPGMLHKMLAAFGWREINL
                     SKIESRPLKTSLGEYFFVIDLLLDRPMTLVENALQEIKMLGGESQILGCYPVLTVEET
                     RR"
     gene            complement(7811..8320)
                     /locus_tag="ACG8LA_001972"
     CDS             complement(7811..8320)
                     /locus_tag="ACG8LA_001972"
                     /EC_number="2.7.1.71"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004765 - shikimate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HFQ0204266.1"
                     /translation="MASILLIGFMGAGKTTIGKGLAQCLQKEYVDLDTKIEEHIQLSI
                     AEYFHYYGEKSFRKVESDILRKLSNEDKIIATGGGIVQSAENRRFLKTQPIVLYLEAE
                     ADCLVDRIQQDETSIRPLALGKTREEIKALLAQRLSWYEESATHRINTTNQTPEKIID
                     TIIERIKSI"
     gene            complement(8313..9608)
                     /gene="aroA"
                     /locus_tag="ACG8LA_001973"
     CDS             complement(8313..9608)
                     /gene="aroA"
                     /locus_tag="ACG8LA_001973"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003866 - 3-phosphoshikimate
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HFQ0204267.1"
                     /translation="MQLLQQIHGLRGTVRIPADKSISHRSIMFGAIAEGTTTIQNFLR
                     AEDCLSTLHAFQQLGVEIEEEEEVIKIHGRGSHSFVQPTESIDMGNSGTTIRLLMGIL
                     AGQPFTTTLFGDASLSKRPMGRVMEPLREMGADLQGEENDQYLPITVTGTRSLSPIRY
                     NMPVASAQVKSALLFAALQAEGTSVIVEKERSRNHTEEMIRQFGGRITVEDKTIIVTG
                     PQKLTGQQITVPGDISSAAFFLAAGLLVPESQLLLKNVGVNPTRTGILDVLEEMGAAI
                     TQTNHNEQNQSADLSVKTSHLKKATIGGEIIPRLIDELPILALVATQAEGITIIKDAE
                     ELKVKETNRIDAVAEELQKMGAKIKATADGLIIHGPTPLHGAKVSSRGDHRIGMMLQV
                     AALIADGPCELEGAEAVSISYPAFFDDLAELVSGGEAHG"
     gene            complement(9621..10712)
                     /locus_tag="ACG8LA_001974"
     CDS             complement(9621..10712)
                     /locus_tag="ACG8LA_001974"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HFQ0204268.1"
                     /translation="MAQHVFIVGLGLIGASMALCIRQTNPELIVVGWDSQSKTREQAV
                     EQQIVDYVASDFETGAEQADVILLAVPVRTTLAYLDVLERINLSDHVIITDVSSTKQQ
                     VVTSAEQKNLRFVGGHPMAGSHKSGIQAADAKLFENAYYIFTPLEKTKKDVEKLQELF
                     CGTKAKYVTLTAREHDRITGMLSHFPHILAAGLVNQAEQFNQEYPRAKQLAAGGFRDI
                     TRIASSDPVMWTDILLSNKQILLERLADWQQEMTQIAEWIMTENQSEIFSFFNRAKES
                     RDQLPVHKQGAIPAFFDLFIDVPDEPGVIAEVTGLIGKAGVSLINLKIQETREDILGI
                     LQISFKNQQDLLQAKRIIMSNTSYHCWIK"
     gene            complement(10729..11895)
                     /gene="aroC"
                     /locus_tag="ACG8LA_001975"
     CDS             complement(10729..11895)
                     /gene="aroC"
                     /locus_tag="ACG8LA_001975"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004107 - chorismate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HFQ0204269.1"
                     /translation="MRYMTAGESHGPELTAIIEGLPAGLPLSEEEINHELARRQAGYG
                     RGGRMKIEKDRVRITSGIRHGKTIGSPVTLVVENKDWKNWTTVMSVAEVPEKDQSLRR
                     VARPRPGHADLVGGMKYHHRDLRNVLERSSARETTMRVAIGAIAKKILEELDIIVAGH
                     VICLGGIQAEIPGNISIQEIKEISEASEVRVVDPAVEQRIKDLIDQTKKNGDTIGGIV
                     EVLVGGVPAGLGSYVQWDTKLDAKIAQAVVSINAFKGVEFGVGFTSGSLPGSEVMDEI
                     LWEEERGYFRRTNNLGGFEGGMTNGEPLVIRGVMKPIPTLYKPLQSVDIDTKEPYKAS
                     VERSDSTAVPAASVVAENVVATVVATELLSKFPSDSLVELKAAVKEYRDYLKHY"
     gene            complement(11897..12961)
                     /gene="aroB"
                     /locus_tag="ACG8LA_001976"
     CDS             complement(11897..12961)
                     /gene="aroB"
                     /locus_tag="ACG8LA_001976"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003856 - 3-dehydroquinate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HFQ0204270.1"
                     /translation="MLTVHVDNQKYDIHIEKGALEQAGSWLQTIWRPQKVAVITDTNV
                     APLYAEKIMFQLRQANFEPVLSIVPAGETSKSLEQAAELYDFLADNDFTRSDGILALG
                     GGMVGDLAAFVASTFMRGIHFVQIPTTLLAQVDSSIGGKTAVNTNKAKNLVGTFSQPA
                     GVLIDPEVLKTLPVRRLREGIAEIIKSAAIADATLWKQLNELKDEKDLLEHAVPIITA
                     TLEIKRKVVEEDVFDQGNRLILNFGHTIGHAIENTAGYGVVSHGEGVAIGMVAITSHA
                     EKIGLSPTGSTAALERILQKFHLPITYDLSHPDELFHAITHDKKARGSQLNIILLEKI
                     GQAKIVPVPTETFKDYLGGL"
     gene            complement(12994..14016)
                     /gene="aroF"
                     /locus_tag="ACG8LA_001977"
     CDS             complement(12994..14016)
                     /gene="aroF"
                     /locus_tag="ACG8LA_001977"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003849 - 3-deoxy-7-phosphoheptulonate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HFQ0204271.1"
                     /translation="MIVIMKKEATEEQIKKVVDHIEKEGFKVSIDQGTERVVIGLKGD
                     TRSLQEGAFTRYEGVENAVRILNTYKLTSREFHPGNTVVDVDGVKIGDGSFVTMAGPC
                     SIEGLDQIRECARMAKAGGAKILRGGAFKPRTSPYAFQGLEEEGLKYIRQAADEFGMK
                     VITEVMDEGHIDMVAEYSDILQIGARNMQNFKLLSAVGKTGKPVGLKRGISGTINEWL
                     NAAEYIAVEDKSPVIFIERGIRTYETATRNTFDLSAVPLMKKLTHFPVIVDPSHGTGI
                     WELVPPMARAGVASGADGMIVEIHPDPANAWSDGPQSLNEKTYSRMMKEVAIMKEAME
                     KIQTLD"
     gene            complement(14675..15649)
                     /locus_tag="ACG8LA_001978"
     CDS             complement(14675..15649)
                     /locus_tag="ACG8LA_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase small subunit"
                     /protein_id="HFQ0204272.1"
                     /translation="MKNTVNKSHMDTEKVAIVFGDCTLGVKSGNTHYIFSYTRGGLES
                     LNKNGKEWLYRETLPVFWRATTDNDRGSGFGFKSGMWLGAGLYPKVKEIEVLVDNKKI
                     DLPIAPVNNQYSSNEYAETVEIIFTLEINTVPKTQVTISYQIAGEGKMLVNMHYYGQK
                     GLPELPALGLRFIMPTKAKFFEYEGLSGETYPDRMAGGVEGIYKVAGLPVSPYLVPQE
                     CGMHMETKWVELTRNQTLDNTDKDQEDFSLRFEQQDTPFAFSALPFKAEELEQATHIE
                     ELPPERRTVLTIFAKVRGVGGINSWGADVESPYRISSEEDHEIGFIIQ"
     gene            complement(15630..17513)
                     /locus_tag="ACG8LA_001979"
     CDS             complement(15630..17513)
                     /locus_tag="ACG8LA_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2 TIM barrel-domain
                     containing protein"
                     /protein_id="HFQ0204273.1"
                     /translation="MKANIKWLDDPQVFRVNQSNAHSDHVCYATREEVETTSSLKQSL
                     NGSWRFCYSPNPSVRPKTFYKKDFDACSFDEITVPSHIELANYDKIHYINTMYPWEGH
                     VFRRPPFTTSPEKEAEGIFSAAKDNPVGSYLTTFRLEEGLKGKQISIHFAGVEQAMFI
                     WLNGHFIGYAEDSFTPSEFDLTPYLEEENILAVEVYKRSTAAFLEDQDFFRFFGIFRD
                     VFLVARGQNHLEDLWIKPRLDDKCQNGKLEVDLSFEQVAKNSQLNVAILDPDGKEIYQ
                     QQYPLKEQMTIRIDGFENVALWGHFQPNLYKLELETIDEEKRVTEYIDYSFGFRKIEI
                     KDKIIYFNGKRMIINGVNRHEWHPKKGRAITIEDMEKDLAIIKNAKINGVRTSHYPNQ
                     ITWYYLCDQAGIHVMAETNLESHGSWQKMGAFEPSYNVPGAVPQWQAAVLDRAKTNFE
                     TLKNHPSILFWSLGNESYAEENIRQMNDYFKKVDPDRLVHYEGNFPNPAFEDSISDVK
                     SCMYAPQEEIIDYLENKAEKPFILCEYMHDMGNSLGGMDSYMTLLDRYEMYQGGYIWD
                     FKDQAIQVTDPITGREVMRYGGDFDDKPSDYEFSGNGIVFADGQEKPAMQEVRYYYEK
                     YSK"
     gene            complement(17531..19756)
                     /locus_tag="ACG8LA_001980"
     CDS             complement(17531..19756)
                     /locus_tag="ACG8LA_001980"
                     /EC_number="3.2.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HFQ0204274.1"
                     /translation="MDITHRKTDKNFILFDEKSRVFHLRNTFLSYLIKIEESNVLAHI
                     YFGKPVKQYKDNKNYPRRDRGFSGNVPLNPDRSLSKDTLPQEYSSHGSMDFRTPASII
                     QRKNGSDLLDLRYDSHYITDGKPEIEGLPQTYVMDKSEAQTLVISLKDRETAIYFDLF
                     YTIFTDRAVITRSVKIRNETGETIKLEKAASFQLDFAHTRRFDEVIALPGAHVNERQI
                     SRQSVLSGTKVFESRRGTSSHHMNNFIALVHHHTTENTGEAIGLQFVYSGNHSFELEK
                     DQINQLRVVGGINSHRFSWELNAGQSFQTPEMILSYSSQGLNKMSQIHHELLRERIAR
                     GRHQFAERPILVNNWEATYFDFNSEKIKAIIDEAKELGIEMFVLDDGWFGKRDADNSS
                     LGDWFEYEGKLTNGLREIADYAHSKGLKFGLWFEPEMISVDSELYRTHPDFLMQEPGR
                     MPSASRSQHVLDFTRLDVRQTIEKQMRKILDTIPLDYIKWDMNRSLSDVYSITLDPQR
                     QGEVAHRYMLGLYELLEHLTTDYPEILWEGCSGGGGRFDAGFIYYMPQSWTSDNTDAV
                     ERMKIQYGTSLAYPISSITAHVSAVPNHQTDRSTSLKTRGETAMSAVFGYELDLTKLS
                     PEEKKQVKDQIISYQTIRPVIQYGHYYRLASPFEENIAAWMFVSPKQDEAIVFLGRIL
                     ASAQPAFHEVYLMGLDDEALYQEQTSKRIFSGAELMTVGLYFPDFQGDFQTELLHFKK
                     L"
     gene            19871..20905
                     /locus_tag="ACG8LA_001981"
     CDS             19871..20905
                     /locus_tag="ACG8LA_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFQ0204275.1"
                     /translation="MVGIRDVARKANVSPATVSRVLNNDQTIHVAQTTRQRIVEAAAA
                     LDYDISTRKYIKKRMPSIGVISTIGKASEEQDIYYKHLRVGMEEEARRLHLGMNRIYN
                     LSDNPKQWEDLDQLGAVIVVGTVTKESITALLKQNMQIVVVDNPDIQQEVDMVYADLE
                     RMTKTVLELFLENGHKRIAYIGGYKVDMDEFGGKQISINEKRMRAYQHFMIDHHLEKY
                     MSYHLGGWTEKQGEVLATNLLENESPLPTAILVGSDPMAIGVYRALKQKNIQIGEEIV
                     VASFDNIETIANLSPGLTSVQINAKSIGQAAVRMALERIDGIRDEPIILTYPARLIVR
                     ESFIPRTKRY"
     gene            complement(20972..21985)
                     /locus_tag="ACG8LA_001982"
     CDS             complement(20972..21985)
                     /locus_tag="ACG8LA_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFQ0204276.1"
                     /translation="MKKKILKFIGWFFGIILGIAFAIFLAFQLSPRPGAFLINHMFSN
                     TVQITDKKTFDQAEKNVAKKTDLTYESKYKENTYDIYYPKNSKGPVPVLFWVHGGGFV
                     GGDKSGVKEFATKLVSDANIAVVAMNYELAPDSEYPNQVLQVNELIKDLLAEEKDDKL
                     LDMEQLFFGGDSAGSQIALQYAAIQTNDAYAKQMKIKQLLPKDSLKGTISYCGPVDLK
                     LTAQQHSDDRFMKFFVKTVAWSLIGTKDWKTSEQLKEASVADHVSKEFPPTYITDGNA
                     YSFQEQGQALENRLTELKVPVQSLFYTDTKKEITHEYQFDYTLKESQNCYQQTLDFVN
                     KYK"
     gene            complement(22063..22251)
                     /locus_tag="ACG8LA_001983"
     CDS             complement(22063..22251)
                     /locus_tag="ACG8LA_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine synthase"
                     /protein_id="HFQ0204277.1"
                     /translation="MEEHQQVIDRIYEATRYLPLDRLCLSPQCGFASTEEENVLFEEQ
                     WKKFLLSKALQKKFGENH"
BASE COUNT         6450 a         4863 c         4094 g         7230 t
ORIGIN      
        1 acaatcagga cagtcatcgg caatatagca gcaatcactt ctttaaaatt ttttagcatg
       61 tatcctcctc ctttactctt taagtttacc ttaaaatgaa agagttttcg agcacaaact
      121 taaaacgtta tcatttaatt tttctcaaca taaaataaca cacgtcccaa aagtatcttt
      181 ttacttggaa aaatgacttt gaaggaacgc gcttattgtg tttttttatt ttacagagcc
      241 gatcattcct tgaacgaatt gcttttgcaa aacaaaaaat acgatggcag ttggtaaagt
      301 agcgatgact aatccagcca tgatcattcc atagtctggt gtataggaag cacccatagc
      361 agataaaaca agcggaaccg tccgtttatc aggagattgc aaagctacta agggccataa
      421 ataattgttc cagctactca tgaatgtgat gattgcagcc gcggcatagg tatttttagc
      481 cgtcggcata tacactctaa aaaaaatact tagttctttt agaccgtcta atcgagcggc
      541 ttctactaga tcttttggaa aagatttaac attttgtcga aagaagaaga tcaaaaaagc
      601 agtgctaaca gatggcagga tgacaaccaa gaaactgttg attcccaaaa ccgttccgtt
      661 caattgtgaa aacattcgat ataaagggat catcaatgcc gcaaaaggaa ccatcatcga
      721 tagcagtaga atattgaaaa ttaggtcttt tcgtttactt tgataaatct caaatccata
      781 tcctgccatt gacgaaatca gcaatgcaaa cacagtggtc accaaagcga tcatcgctga
      841 attccaaagg gaacgagtaa aattcagctc attggaaaac aaattttgaa aattgatgat
      901 caagttactg ccaatcttta tttttcccga tgtgatatcc acgggtgtat tcgtcattcc
      961 caaaaccatc cagacaaaag ggaaaatgga aataaatgat aggatgctta atgctgtata
     1021 ctttaatact gacccaattg tcgaacgaag ttctaatgct tgttttttga cgttggggcg
     1081 ttcgattgtt tctttttcta ccatattttt catcgacttt ctcctcctac tttcgtttgg
     1141 attatcgaca atatcacaat aaaggaaaca ataacaaagg aaactgctgc cgcatatcca
     1201 aaattaggcg tgaatttata actcaaatta tagatgtatt gagatagggt ggtcgttgca
     1261 tttgctggtc ccccgccagt aatattttgt acttcatcaa aaagctgcaa tgtcccgatc
     1321 gtcgaagtaa tggaagtaaa caaaatgatt ggttttaaat ttgggatcgt cactttgata
     1381 aactgctgcc atttagaagc accgtcaata gatgctgctt cataaatctc cgaatcaata
     1441 ttttgcatgc ctgaaaggaa aaaaatcata ttgtatccag tccaacgcca agtgatcgaa
     1501 agaatgatca gaactctcgc ccaaattgga tgagtcaacc agccaatcgg tgtgtcaatc
     1561 ataccaatgc ccaacaacaa gttgtttaca aggccagatt gagaaaatag acttttcatg
     1621 atcagagaat aactgaccat cgaagtgata catggaagaa agatagcggt tcgaaacaac
     1681 cctttatatt tcaacttttt atcatttaaa aggttggaaa taaaaagtgc tagaaacaac
     1741 atgatcggta cttgtacaag taaatacagg aatgtattaa aaaaagcttt tttaaaagtt
     1801 gcatctgtca acatccgctg ataattacct aacccgttaa atgtcatatt gacaggggga
     1861 ccactttgaa aagacgtgat caaagccaaa accatcggaa taaaaaccat gattgatatc
     1921 aaaatgactg gcaagattaa aaaagcatgc ccgtttttga ataaatcttt ctgcttcatt
     1981 cttttccctc caattctatc attgattatc tacatgaaaa gacaagaaag acaatatctg
     2041 taaggcagac gtgatctttt ttgtcttttc gtttgtctga tgaaaaagcg aagaaattca
     2101 cttttttacc accgatcaat tagccaattg tgcttctact tgtttttgtg tatctgctag
     2161 taccttgtct gtctcttctc cattgatgat tcgatgaaga gcttcagcta cgactgcttc
     2221 aattgcatag gtctcatgtc cgtaattcac ttctggtatt tcagatgtcc atgttgaaaa
     2281 atcgtcaaag atcttttgac cactgtaaaa ttcagaagct tcttgataag cttcttgttc
     2341 attcgcgcta agcatcgtag atactagtcc gatttctttc gcaagagtgc ccatcagttc
     2401 ttcattcgaa gcaaacgttg cttctaggaa atctttcgct gaatcttctc cagctactcc
     2461 tttgatcaca taccagccag cgccgccaag gttagaagct tgcgcttttt gcagattttc
     2521 tggaagtgca ggtattggtg caatcttcca ttttccagat tggttttctg ctccttggat
     2581 cgttgaagaa taccaagcgc cagttgggct agaagctact gctcctgatt gtatcgcagt
     2641 tactccagca ttccagtcag aggtttgttc gactagatct tctttcaaaa gagtggcaaa
     2701 caattcaaga ccatacttta aagatgcatt gtcttggatc gtgactgtct ccccatcttc
     2761 agatgtatac cattctcctg cctgttgcat aatcatcctt actcgaccaa ggtcagaagg
     2821 attgacttca gcgattttct ttcccgtctt ttctttgaca tctcgcgcta cttgaatata
     2881 ctcgtcccac ttcagattct ccatatcctc ttctgtataa cctgcttctg ccatcagatc
     2941 cgtacgatag aagtttgctg ttacgcccga atcgaaagga acaccgtata ttttatctcc
     3001 tactttgttt accgcaaatt tatacggtgc aaaatgatct tcctttacaa tagcagacaa
     3061 attagcgaat gcatctggat aagaagtcaa atagccttgt atcctataat cttcaatcaa
     3121 gacgatattg ggcaatcctt ctgtattccc gctcgctaaa gcggtgttca gtttctgaac
     3181 gatatcatcc tgagacatcg taacaacttc tatctctgtt tcttcgttct cataaacttt
     3241 ttttgcttca ttcactgctt tgatattgaa tgtctcatcc cacgcccaga cagtgacttt
     3301 ttcttctttg tctgctgtac tactagcact tccgcatcct gttaagaaac ctgatgctgc
     3361 cgctaaacaa acgactccag caattaactt tctgatgttc atttttatcc gctccttttc
     3421 catccattag ttgtttacgt ttgctacatt catcatacca aaatttgaaa acggtttctt
     3481 tattattcag atacttcaaa aatttctcct aaaataataa aaaaatacaa atcaactatg
     3541 acaaaaggaa taatcttagc atctagacca aagatcgaaa tggtgaggtt tctttaaaat
     3601 aaaaatatcc ttgcattttc tcctagaaat aagtattttt aaattacaag actattctta
     3661 aggcgggtaa aaaaatgcca atacgcgtaa ttcttatcga tgatgaacag acgattttag
     3721 atggaatgaa acagttgatc aattggtctg agcacgggtt tcaattaata gggacttttt
     3781 ccagtccgct gaaagcgctt gatttttctt tggtacatgc aatcgatatc gtggtcacag
     3841 atgtaatgat gcctgaatta aatggaatcg aattatcgcg gctattaaaa cagcaacaac
     3901 ctgaaacaca gatccttatc ctctctagct atgatgaatt tgatatggtt aaagattctt
     3961 ttaaagaagg cgtcgctgat tatcttttaa agcctcgatt gagtcctgat ttttttctaa
     4021 attccttaac tgccgtttca caaaaaatca aaaaaaagcc caacaaaagc ccaatcacca
     4081 atcgttatga gcagatctgc gagaatcttt cacagcagat tgctggacaa actcgtccat
     4141 tgcttgaccc tcttcttttt gaacacacct tgtttttctg ttatataccg aaaaacggcc
     4201 attcagttca aaacaaggct ctaaacaaaa acagtcgatc acccattcat tgatggatag
     4261 cgacgattcg tttactattt atcctgtttc taccttttcg gaagaatccg gctatgtaat
     4321 caatactgat tccaaagata cacttaggaa gtttgttcaa aagtttcgtc aagaagtttt
     4381 tccaggtgat ttttttgttg tttctgattc ttttgcaatc caagatatca atgaaatatt
     4441 ccaagagatc agaaattgca ccaaaggaca acgtttctat cataagggaa agaaccttgc
     4501 ttatcagcat gaacttcttc cgttattaac caaccacgag cagcaagcaa gtagttattt
     4561 aacaaaaatc gttcataaag actacgcttt agctgtcaaa gaacttgaga atttcttcac
     4621 gacgatattg gaacagccta ttgatccagc ttatttgaaa catgaggcaa tcaatcgttt
     4681 ctatgcatta ctcaacgctt tggctgacga gcatgttggg aatgaagaac tttctttgct
     4741 caagatcgcc cttccttctt tattagccga tgctgagtat ttcgaagatt tttctattct
     4801 tgtcaaagaa acacttgaga aactcaccca cttttctgca aatgcaaaaa aagacaattt
     4861 cgatatcttg actttgatct acgagttcgt ccaggaaaat tatgagaaag aaatcaattt
     4921 acaactttta tccgaaaaat atcatttttc atatagctat ctctcagcca tctttactga
     4981 aaaatttggt atcaactttt caaaatatct aaaaaaagtc cgtatcagta aagccaagct
     5041 ctttttgacg gaaacacggc ttactttgac ggaaatctgt gagaaagtcg gctataccga
     5101 actgggttat ttctccagag tttttaaaga agagacagga atgacacctt ctcaataccg
     5161 taaaggaact tttgtaaaat gagaaaaaaa atcaaagagc atgaactctt tgccaaactt
     5221 ctgttcattt tgttcatcgg tctttttctg caagccatcg tcatttcttt gtttatttat
     5281 catcgatcaa gggatgccta tatccagctg ttcaatcaat cgaatgatgt ggtactaaaa
     5341 aagattcaat ctgaatttga aagtttgaat gatacaatcg agaatacatt agccgctttt
     5401 gattctaatc cagctgtcaa aagctatttt tccaatgatc cagcccaaca tatggaacag
     5461 cttcagcaac taagaacaat ccaaaaaatg aatgactctc tttcaaaaat ccatccaatg
     5521 atcgattacg atgtattgat ctttggagaa aatggaagaa cttttgtcgg aaacgacatg
     5581 ctcactgccg tatctgccga ttcttttttt caatctgcga ttgctcagag agtgaatgaa
     5641 cgtgctgctg atacacaaat gctttttgca caccacggat tgactcttcg cgataagaaa
     5701 gcacccagcg tcttctttgt caaaaaactg aaaaatacat tgaatcacgt ttacggatat
     5761 gctgttttat cgatctcatc caagcaacta gcgaatcttt ttcaatctgt agtaaatcct
     5821 gagatatcga agatctcctt catgaacgaa gaacagacga tcatcgcatc aaatgaagaa
     5881 aatacaattg ggagccgatc aatgattttc aaaaaactaa cagtaggtga aacaacgatt
     5941 tcaaatggac agcagttgac ccgtcttcct ctgtaccgcc aggattgtac attactcagt
     6001 caagtcgatc ttcattcttt atctaaccaa atgggcgtga tttttccgat tattttgtat
     6061 aatatcgtga cacttgcttt tgctggctca ttggtattta tgtatttgga tcgacacaca
     6121 aaatcgatct accgcttgat tgattcgcta aaacggctag aggaagatgg cttaaaagct
     6181 actgttcctg tacaaggaag ccatgaagtc caattgctag ggaatacgat caatcaattg
     6241 ctaagtaatg ctcagcatca ttatgaacag acgatccaag acgaaaagaa gaaacgttcg
     6301 cttgaaatcc aaactatgca agcacagata cagccccatt ttatttataa tacgctgact
     6361 agcttgaaat ttttgatttg gcagaaaaaa acagatgaag cagttcaagg aatcgacagt
     6421 ttcattactt tactaagaag tacgattggg aaaaaagaag aagtgattcc agtcaaggaa
     6481 gaaatcaaaa gcgtacaaag ttacatcgat cttttgagta tgcgatatgg cgaaagaatc
     6541 tcggctaaaa taatgattcc tgatgaactg cagtcattat ctatgccgaa tatgatcctt
     6601 caaccaatta tcgaaaacgc ctatcttcat gcttttcaca ataaaacgca aggattcatc
     6661 acggtgtacg gcaaaacaaa aaatcagctt cttttattcg aagtgattga taacggcgat
     6721 ggcttcgata ctgaaaatac caaacaaaaa aatgatcatt tttcaggaat cggcatcagc
     6781 catgtagatg agcggatacg cctaatgtat ggcgatgcat atggcttaac gatccaatca
     6841 gtgattggga caggaacgac tgtaacgatt tgtctaccgc ttcttcctaa aaatcaatca
     6901 gaatatcaaa aataaagaat agccaagcgc tgattttttt attttaagtt aaataaatca
     6961 atcagtattc ttgactttca tctacgcgtc tcttctactg tcagcactgg ataacagccc
     7021 aatatttgac tttctcctcc gagcatcttg atttcttgga gcgcattctc tactaatgtc
     7081 attggacggt ccaacaacaa atcgatcacg aaaaaatatt ctcccaagct agttttcaat
     7141 ggtcgggatt caatcttact taagttgatt tcccgccagc caaaagctgc cagcatttta
     7201 tgaagcatcc ctggccgatt agcaggtagt gtcaagatga cactcatttt tactggagct
     7261 gactgctggc tggtcatctt tcggtcaccg acgatccaaa aacgtgtctg gttcaactca
     7321 ttatcttgga tattctcagc taagatctcc aatccaacat gctgtgctgt ttctaatgaa
     7381 gcaatcgctg ctgcgtcttc tttcggatgt tctgctacat acattgctgc agcagttgtt
     7441 gattctgttg ctactaaagg aacattagga taatgcgttt ctaaaaactg ttgtgattgt
     7501 gctagtgctt gtggatgtga aaggattttt gtaatctttg ttgctggatt gcctaaaagc
     7561 tgctgcttga taggaagaac gatttcactt ttaacttcga cttctggatg tttggaaaga
     7621 agatcgattg tgtgatgaac agctccttcc aatgaattct ctacaggaac gacagccaga
     7681 tcgacttgtt tgcgaaacaa agcgcgcaaa caaacaggga tggaagcata cgcagtcaat
     7741 tgttctgtag gaaatagctg acaagccgcc tgataagtga atgaactttc tggccctaga
     7801 tagctgacgt tcatatgctt ttgatccttt ctataatggt atcgatgatc ttttctggtg
     7861 tttgattggt cgtgttgatt cgatgtgtcg cactttcttc ataccaagaa agtcgttgtg
     7921 ccaataatgc ttttatttct tctcttgttt ttccaagagc taaaggtcga atagacgttt
     7981 catcttgttg gatacgatca actagacagt ccgcttctgc ctctaagtaa agaacaatcg
     8041 gctgtgtttt taaaaaacgc cgattttctg cactttggac aatccctcca ccagtcgcga
     8101 taattttgtc ttcatttgac agctttctta aaatatctga ctccactttt cgaaagcttt
     8161 tttcaccgta atagtgaaaa tattcggcaa tcgacaattg gatatgttcc tcaatctttg
     8221 tatctaaatc tacatactct ttttgtaaac attgagctaa ccctttaccg attgttgttt
     8281 ttccagcgcc catgaaacca atcagcaaaa tgctagccat gagcttctcc tcctgacaca
     8341 agttctgcta aatcgtcaaa aaatgccgga taagagattg aaacagcttc agctccttct
     8401 agttcgcaag gtccatcagc tatcaaagca gctacttgca gcatcatacc gattcgatga
     8461 tcgcctctgc tggacacttt tgcgccatgc agaggtgtcg gcccatggat gatcagaccg
     8521 tctgctgtcg cttttatctt tgctcccatt ttctgtaatt cttctgccac cgcatcaatt
     8581 ctgttggttt cttttacttt taattcttct gcgtctttga tgatcgtgat tccttctgct
     8641 tgagtagcca ctaaagctag aatgggcaat tcatcaatca gacgcggaat gatttctcca
     8701 ccaatcgttg ctttcttcaa atgactcgtc ttgacactta aatcagccga ttggttctgt
     8761 tcattgtgat tcgtctgggt aatcgctgcg cccatctcct ccaacacatc taagatacca
     8821 gttcttgttg gattgacccc gacatttttt aacaacagtt ggctttccgg aacaagaagt
     8881 cctgctgcta gaaagaaagc agctgatgaa atatcacctg gaacagttat ctgttgacca
     8941 gttaattttt gcggtccggt cactatgatc gttttatctt ccactgtgat ccttccgcca
     9001 aattgacgaa tcatttcttc cgtatggtta cgggaacgtt ctttttcaac gattacggat
     9061 gtgccttctg cttgtaatgc cgcaaacagc aaagcagatt tgacttgcgc actggctaca
     9121 ggcatattgt atcggatagg tgataaagag cgggttcctg tcacagtgat tggtagatac
     9181 tggtcatttt cttctccttg caagtcagcg cccatctcgc gtaaaggttc catcactcgc
     9241 cccattggac gtttagacaa cgaagcatcc ccgaacagag tagtcgtaaa aggctgtcca
     9301 gccaaaatac ccatcaataa acgtatggtc gtaccggagt ttcccatgtc aattgattcg
     9361 gttggttgga caaatgagtg gctaccgcga ccatgaatct tgatcacctc ttcctcttct
     9421 tcgatctcga cacctaattg ttggaaggca tgtaaagtac tcagacaatc ttctgcgcgc
     9481 aaaaaatttt gtatagtcgt cgttccttca gcaattgctc caaacatgat gctgcgatgg
     9541 gaaattgatt tatctgctgg tatcctaaca gtccctctta atccatgtat ttgttgtaat
     9601 aattgcattt atccagcctc ctatttgatc cagcaatgat aactggtatt agacataatg
     9661 attctttttg cttgtaacaa atcctgttgg tttttaaaac tgatttgcag tattcctaaa
     9721 atatcttccc tggtctcttg gatcttcaaa ttaatcaaag aaactcccgc ttttccgatc
     9781 agtccagtta cttctgcaat aacgccaggt tcatctggca catcgataaa taaatcaaaa
     9841 aaggcaggaa tcgcgccttg cttatggaca ggcaactggt ctcgactttc ttttgcccga
     9901 ttgaaaaaag aaaagatttc cgattggttc tcagtcatga tccattctgc tatttgtgtc
     9961 atttcttgtt gccaatctgc caatcgttcc aataatatct gcttattgct caacaaaata
    10021 tctgtccaca tgacaggatc tgaggaagcg atcctagtga tatctcgaaa gcctcctgct
    10081 gccagttgtt tggctcgcgg atactcttga ttgaattgtt ctgcctgatt gactaagcca
    10141 gctgccagaa tatgtggaaa atgacttagc attcctgtta tacggtcatg ttctcttgct
    10201 gtaagagtta catattttgc tttggttccg caaaatagtt cttgcagttt ttcaacatct
    10261 tttttcgtct tttccaaagg tgtaaagatg taataggcat tttcaaatag tttagcatct
    10321 gctgcctgta tacctgattt atgagaacca gccattggat gtccaccgac aaaccgaaga
    10381 tttttctgct cagcggatgt cacgacttgc tgcttcgtac tgctgacatc cgtaatgatg
    10441 acgtgatcag acaagttgat tctttcaagg acatcaagat aagctaaggt tgtacggacg
    10501 ggaacggcta ataagataac gtctgcttgt tctgcacctg tttcaaaatc acttgcaacg
    10561 taatcaacga tctgctgttc tactgcttgc tcacgggttt ttgactgact atcccaacca
    10621 actactatca gttctggatt ggtctgacga atacaaagtg ccatagaagc accaatcagt
    10681 ccaagcccca cgataaaaac atgttgtgcc atcttatttg cccccttttt agtaatgttt
    10741 caagtagtca cggtactcct tcactgcagc tttcaactca acaagcgaat cacttgggaa
    10801 ttttgacaat agctctgtcg ctaccacagt ggctacaaca ttttccgcaa cgacgctagc
    10861 tgcaggaact gctgtactat ccgaacgttc tacacttgct ttgtaaggtt cttttgtatc
    10921 gatatcaaca ctttgaagtg gcttgtacaa tgtaggaatg ggtttcatga ccccgcgaat
    10981 gacaagtggt tcgccattgg tcattccgcc ttcgaagccg cctagattat tggtacgtcg
    11041 gaaatagcct ctttcttctt cccataggat ctcatccatc acttctgagc ctggtaatga
    11101 accagaagtg aatccgaccc caaattctac gcctttaaag gcattgatac taaccacagc
    11161 ttgtgcgatt ttggcatcta gcttcgtgtc ccattgtacg tagcttccta atccagctgg
    11221 aacgcctcca acgagcactt ctacaattcc tccgatcgta tctccatttt tctttgtctg
    11281 atcgatcaaa tcttttattc tttgctcaac tgctggatca acaactcgta cttctgacgc
    11341 ttcagaaatt tctttgattt cttgaatcga gatatttcca ggtatttctg cttggattcc
    11401 accaagacaa atcacgtgtc ctgctacgat gatgtcaagt tcttccagaa ttttcttggc
    11461 aattgcgccg attgctacac gcatggtcgt ctctcttgca gaggaccgtt caagcacatt
    11521 ccgaagatct cgatgatggt atttcatacc gcctaccaaa tccgcgtgtc ctggacgcgg
    11581 acgtgcaact cgccgcagtg attggtcttt ttcaggcact tctgctacag acatgacagt
    11641 tgtccaattt ttccaatctt tattttctac cactaaagtg acaggtgaac caattgtttt
    11701 gccgtgacgg atgccagacg tgatccgaac acgatctttt tcgatcttca tccttcctcc
    11761 tctgccgtaa ccagcttgtc tgcgagcgag ttcgtgattg atttcttctt ctgacagagg
    11821 taatcctgct ggtagtcctt caataatggc tgttaattct ggtccatggg attctcccgc
    11881 agtcatataa cgcatcttac agtcctccta agtaatcttt gaatgtctct gtgggaacag
    11941 gaacgatttt tgcttgccca atcttttcta gcaagatgat attcaattgg cttcctcttg
    12001 ctttcttatc atgggttatc gcgtggaata attcatctgg atgacttaga tcgtacgtaa
    12061 tcggcagatg gaatttttga agtatccttt ctaaagcagc tgtcgatcca gttggagaca
    12121 agccgatttt ttctgcatga gaagtgatgg ctaccattcc aatagctact ccttctccat
    12181 gactgactac cccatatcct gctgtatttt caattgcatg gccaattgta tgaccaaaat
    12241 ttaaaataag tcgatttcct tggtcaaaga catcttcttc cactactttt cgtttgattt
    12301 ccaacgtagc agtaatgatt ggaacagcat gttccagaag atctttttcg tctttcagct
    12361 cgttcagctg tttccaaagc gttgcatctg ctatagctgc tgatttgatg atttcagcga
    12421 ttccttctcg taaacgacgt accggcaaag tttttagaac ctcaggatca atcaatacac
    12481 cagctggctg gctaaatgtt ccgacaaggt ttttcgcttt gtttgtattg actgctgtct
    12541 tcccgccaat actagaatct acttgtgcaa gtagcgtagt cggaatttga acgaaatgga
    12601 tcccacgcat gaacgtcgag gccacgaatg ctgctagatc acccaccatt cctccaccaa
    12661 gtgcaagtat cccatcgctg cgggtaaaat cattatctgc taaaaaatcg tataactcag
    12721 ctgcttgttc taaagattta ctggtctcac ccgccggtac gattgaaagg actggttcaa
    12781 aattagcttg tctcaattgg aacatgattt tttctgcata tagtggagca acgtttgtat
    12841 cagtgatcac agctactttt tgaggtctcc aaatcgtttg aagccatgat ccagcctgtt
    12901 ctagtgcgcc tttttcaata tgaatatcgt atttttggtt atcaacatgt acagtaagca
    12961 ttcgtttcac ttctttcttt taaaaagctg gaattaatcg agtgtctgaa tcttttccat
    13021 tgcttctttc atgatcgcaa cttctttcat catgcgtgag taagtctttt cattcaacga
    13081 ttggggaccg tctgaccaag catttgcagg atcaggatgg atctctacga tcatgccatc
    13141 tgctccgctt gccacacccg cacgagccat tggtggtaca agttcccaaa ttcctgtacc
    13201 atgacttgga tcaacaatca cagggaaatg agttaatttt ttcatcaatg ggacagcact
    13261 taaatcaaac gtattacgtg tcgctgtttc gtaagtccga atcccacgtt cgataaaaat
    13321 gacaggagat ttgtcttcga ctgcaatgta ttctgcagca ttaagccatt cattgatcgt
    13381 accggaaatt ccacgtttca atccaacagg tttacctgtt ttaccgacag cagatagcag
    13441 tttaaaattt tgcatattac gtgcgccaat ctgtaggata tcgctgtact cagccaccat
    13501 atcgatatgc ccttcatcca tcacttcagt aatcactttc attccaaatt catcagccgc
    13561 ttgacggatg tatttcaatc cttcttcttc taaaccttgg aaagcatatg gagaagtacg
    13621 tggtttgaag gcaccacctc gcagaatttt tgcgcccccg gctttggcca ttcgcgcaca
    13681 ttctctgatt tggtctaatc cttcgataga acaaggacca gccatcgtca cgaaactgcc
    13741 gtcaccaatt tttactccgt ctacatccac gactgtattg ccaggatgga attctcgaga
    13801 agtcaatttg tatgtgttta aaatacgcac agcattttct actccttcat agcgtgtaaa
    13861 tgctccttct tgtaaacttc gcgtatcacc ttttagtcca atcactactc gttctgttcc
    13921 ttgatcgatt gagactttga atccttcttt ttcgatatga tcgacgactt tttttatttg
    13981 ttcttccgtt gcttcttttt tcataattac tatcattgtt tttcccgctt tcttttgttt
    14041 acttatctat cttggctgat tttctctact ttttcaaggt ggttttacat taattcctac
    14101 taaatgaccg tgtcctgttg ttctcatttt cgctccttct ttcctactta tgacccagat
    14161 aatcaacaaa aaaagatgtc cctgtaggaa attgcctcta cagtgaacat cttcaacgag
    14221 ccttaaaaag cgctgcaaaa atataaaata gccactatag atgaatttct ctacgtggct
    14281 gtaagtcgtg tttaaaaatc tttagccatc atagatacaa acctggtttg tttgtaccca
    14341 cgaagtcatg aatacaaacc tatctaaaat agctaaagta atacgtattc agttttgtaa
    14401 gttttctaga tttcataaaa aatcgctcca aactgatgta agaattgtac ctagtataga
    14461 cataaaaaaa tcgactgtca atcattttta tgaaactttt tttaattttc tgatagttaa
    14521 ctttgttttt cagaaaaata acaattggtt ttattgaaga aaatagtcat gaacaaaagt
    14581 atctgagaac ttttttactc tcttgttcat gacatataga ataaagcagc tttgtcttgt
    14641 aaactccgtt tttcaaataa taatctaaag attgctactg aataataaag ccgatttcat
    14701 ggtcctcttc gctgctgatt cggtaaggtg actcaacatc cgctccccag ctattgatac
    14761 ccccgactcc tcttactttt gcaaaaatcg taagaaccgt tcgtctttct ggcggtagtt
    14821 cttctatatg tgttgcctgt tccagttctt ctgctttgaa tggtaaagcg gaaaaagcaa
    14881 atggcgtatc ctgctgttca aatcgcaacg aaaaatcttc ttgatcttta tccgtattat
    14941 ccaacgtttg atttcttgtt agttctaccc atttcgtttc catatgcatg ccgcattctt
    15001 ggggaacaag gtatggggaa acggggagtc ctgccacttt ataaatacct tcgacaccac
    15061 cagccatccg atccggatat gtttcccctg ataggccttc atactcaaaa aattttgctt
    15121 tcgttggcat aatgaacctt aaacccaatg cgggtaattc cggtaatcct ttttgtccat
    15181 aataatgcat attgacaagc attttaccct ctccagcgat ttggtaggaa attgtcactt
    15241 gggtttttgg tactgtgttg atttccagtg taaaaatgat ttcaaccgtt tcagcgtatt
    15301 cattacttga atattgatta tttactggag caatcggcaa atcgatcttt ttattgtcca
    15361 ccagtacttc tatttctttg acttttggat acaatccggc tcctaaccac ataccggatt
    15421 taaatccaaa tccgctacct ctgtcattat cggtcgttgc tcgccaaaaa actggaagtg
    15481 tttcccggta tagccattct tttccgtttt tattgagcga ttccagtccg cctcttgtat
    15541 aagaaaaaat ataatgcgta ttccccgatt tgacacctaa tgtacagtcg ccgaagacga
    15601 ttgcaacttt ttccgtatcc atatgacttt tatttactgt atttttcata ataatatctt
    15661 acctcctgca tggcgggttt ttcttgtcca tctgcaaaaa cgatcccatt ccctgagaat
    15721 tcatagtcac ttggtttatc gtcaaagtca ccgccatagc gcatcacttc tctgcctgtg
    15781 attggatcag tcacttggat cgcctgatct ttaaaatccc atatatagcc tccttggtac
    15841 atttcataac gatcaagcaa cgtcatgtaa gaatccattc cacctaacga attccccatg
    15901 tcatgcatat attcacataa gatgaacggt ttttccgctt tattttcaag gtagtcaatg
    15961 atctcttctt gtggcgcata catgcagctt tttacatctg aaatcgaatc ttcgaatgct
    16021 ggatttggaa aattcccttc ataatggaca agtcgatcgg ggtctacttt tttgaagtaa
    16081 tcgttcattt gtcgaatgtt ttcttccgca taagattcat ttccaagaga ccaaaaaaga
    16141 atacttggat ggttttttaa tgtttcgaaa ttcgtttttg ctcgatcaag aacagccgcc
    16201 tgccactgag gtactgcacc tggtacgttg taagaaggct caaatgcgcc cattttttgc
    16261 catgagccat gggattcgag gttcgtttcc gccatcacat ggattcctgc ttggtcgcat
    16321 aaataatacc aagtgatctg gttggggtaa tgagatgtcc gtacgccgtt gatctttgca
    16381 ttttttatga tagccaaatc tttttccata tcttctatag tgatggcgcg tccttttttc
    16441 ggatgccact catgtcgatt taccccgttg ataatcatcc gttttccatt gaagtagatg
    16501 attttatctt tgatttcgat tttacgaaaa ccgaaggaat agtcaatata ctccgttact
    16561 cttttttctt cgtctatcgt ctccaattca agcttatata aattgggctg aaaatgcccc
    16621 cacagtgcca cattttcaaa tccatcgatg cgaatcgtca tttgctcttt taacggatat
    16681 tgctgttgat agatttcctt cccatcagga tctagtatcg ctacattcag ctgactgttt
    16741 ttggctactt gctcaaaaga caaatctact tcaagtttgc cattttgaca tttgtcatct
    16801 aagcgaggtt tgatccaaag atcttctaaa tggttttgtc ctcgagcaac taagaagaca
    16861 tctctgaaga tcccaaaaaa tcggaaaaag tcctgatctt ccaagaatgc agctgtactt
    16921 cttttgtaaa cctccacagc tagaatattt tcttcttcca aataaggtgt taaatcaaat
    16981 tcagacggag tgaacgaatc ttcggcatac ccgataaaat gaccattcaa ccaaataaac
    17041 attgcttgtt ctacaccagc aaaatgaatc gagatttgtt ttccctttag accttcttct
    17101 aatcgaaaag tcgtcaaata cgaaccaacc ggattgtctt tagcagctga aaagatccct
    17161 tccgcctctt tctcagggct tgtcgtgaaa gggggacggc gaaatacatg tccctcccac
    17221 ggatacatcg tattgatgta atggatcttg tcataatttg ctaattcaat atgactagga
    17281 acagtgattt catcaaaaga acaggcatca aaatcttttt tataaaatgt ttttggtcgt
    17341 accgaaggat ttggcgaata acaaaaacgc catgatccat ttaaagactg tttaagggag
    17401 gatgtggttt ctacttcttc ccttgttgca taacaaacat gatcgctatg tgcatttgat
    17461 tggttcactc taaaaacttg tggatcatct aaccatttta tatttgcttt catacttttt
    17521 tccttctctc tcataacttt ttgaaatgaa gcagttctgt ttggaaatca ccttgaaaat
    17581 cggggaagta aagtccaact gtcatcaatt cggcccccga aaatatccgc ttcgaggtct
    17641 gttcctgata aagtgcctca tcatctaacc ccatcagata tacttcatgg aacgctggtt
    17701 gagctgaagc tagtatcctc cctaaaaaca caatagcttc atcttgttta ggagacacaa
    17761 acatccatgc ggcaatattt tcttcaaaag gactcgccaa acgataataa tggccatact
    17821 ggatcaccgg acgaatcgtt tgataggata taatttggtc ttttacttgc tttttttctt
    17881 caggagacag ctttgtcaaa tccagttcat aaccaaaaac agcgctcata gctgtttctc
    17941 ctcttgtttt caacgaagta gatctgtcgg tctgatgatt tggtacagct gatacatgag
    18001 ctgtgatgga cgaaatcgga taagcaaggc ttgttccata ttggattttc atacgctcca
    18061 ctgcatccgt gttatcactt gtccatgact gcggcatata ataaataaac ccggcatcaa
    18121 accgtccacc tccaccagaa cagccttccc ataagatttc cggataatca gttgtcaaat
    18181 gttcaagtag ttcataaagc ccgagcatat aacgatgcgc tacttctcct tgtctctgtg
    18241 ggtcaagggt aatcgaatag acatctgaaa gcgaacggtt catatcccat ttgatgtagt
    18301 caagaggaat cgtatctaaa atctttctca tttgtttctc aatcgtctgc cgaacatcta
    18361 accttgtaaa atccagtaca tgttgtgatc tggaagcaga aggcattcta cctggctcct
    18421 gcataagaaa atcaggatgt gttcgataca gttcagaatc aaccgagatc atttcaggtt
    18481 caaaccataa accaaatttc aatcctttgc tatgagcata atctgctatt tcacgtaatc
    18541 catttgtcaa cttgccttca tactcgaacc agtctcctaa tgaagaattg tccgcatctc
    18601 tttttccaaa ccagccatca tctaatacga acatttcgat gcctagctcc tttgcttcat
    18661 caatgatcgc cttgattttt tcactattga agtcaaagta agtggcttcc cagttattga
    18721 ccagaatcgg ccgttcagca aattgatgac gacctcttgc gattctttca cgtagcaact
    18781 catggtggat ctgactcatt ttgttcaatc cctgacttga gtaagaaagg atcatttcag
    18841 gtgtttgaaa agactggcct gcattcaatt cccacgaaaa acgatggctg ttgatcccac
    18901 cgacgactct caattgattg atctgatctt tttcaagttc gaaagaatgg ttgccggaat
    18961 aaacaaattg aagtccgatc gcttctccag tattttctgt cgtatgatga tgaactaaag
    19021 caataaagtt attcatatgg tgactgctcg ttcctcgacg gctttcaaat acttttgttc
    19081 cagataaaac agattgccgt gaaatctgtc tttcattgac atgtgctcct ggcaaagcaa
    19141 tgacttcatc aaatcgccta gtatgggcaa agtctagctg gaaactagcc gctttttcta
    19201 gtttgattgt ttctccggtt tcatttctta tctttacaga tcgtgtgatc actgctctat
    19261 cagtaaatat ggtatagaac aaatcgaaat aaatcgctgt ttctctatcc ttaagtgaaa
    19321 tcaccaacgt ttgtgcctct gacttgtcca tcacataagt ttgaggcaag ccttcgatct
    19381 ctggcttccc atctgtaata taatggctgt catatctcag atccagtaag tctgatccat
    19441 tcttgcgctg aatgatcgat gcgggcgttc gaaagtccat gctgccatga gaagagtatt
    19501 cttgcggtag tgtatctttc gacagagacc ggtcaggatt taagggaaca tttcctgaaa
    19561 atccacgatc tcttcgggga taatttttat tgtctttgta ctgcttgact ggtttgccaa
    19621 aataaatatg cgccaataca ttgctttctt ctatctttat cagataagaa agaaatgtat
    19681 ttcgtaaatg gaagactcgg ctcttttcat caaataagat gaaattttta tctgtttttc
    19741 tatgcgtaat atccatcatt tcactcccaa caaaacggaa accgtttact tttttttata
    19801 attcctgtat actgtttact aaacaatttt gtcaataaaa attttttatt tttttgagga
    19861 gtgtgtaaaa atggttggaa ttagagatgt cgcacgaaag gcaaatgtct ctcctgctac
    19921 agtttcccgt gtgttgaata acgatcagac gatccatgtg gctcagacta ctcggcaacg
    19981 gatagtagag gcagctgctg cgttggatta tgacatcagt actcgtaaat atatcaaaaa
    20041 gagaatgcct tcgattggtg tgatctctac gatcggcaaa gcgagcgaag aacaggatat
    20101 ctattacaaa catttgcgag tagggatgga agaagaagct cgacgtctgc atttagggat
    20161 gaatcgaatc tataatctat ctgataatcc taaacaatgg gaagatctag atcagttagg
    20221 tgcggtgatc gttgttggga ctgttacgaa agaatcgatt accgccttgt taaaacaaaa
    20281 catgcaaata gtcgtcgtgg ataaccctga catccagcaa gaggtcgata tggtgtatgc
    20341 agatcttgaa cggatgacta aaaccgtact ggaattgttc ttagaaaatg gtcataaaag
    20401 aatagcctat atcgggggat ataaagtcga tatggatgaa ttcggtggga agcagatttc
    20461 tataaatgaa aagaggatgc gtgcctatca gcattttatg atcgatcatc acttagaaaa
    20521 atatatgtct tatcatctag gtggctggac agaaaaacaa ggtgaggtac ttgcgactaa
    20581 tctattagaa aatgaatccc ctcttcctac tgccattctt gtcgggagcg atccaatggc
    20641 aattggtgtc tatcgggcat tgaaacaaaa aaatatccaa attggagaag agattgttgt
    20701 agcaagcttt gataatatcg agacaatcgc aaacctctcc cctggcttga ccagtgttca
    20761 aatcaatgcg aaatcaattg ggcaagcagc tgttcgaatg gcattggagc gaattgacgg
    20821 tatacgggac gaaccaatca ttttgactta tcctgcacga ttgattgtta gggaaagttt
    20881 tatcccaaga acaaaaaggt attgaaagag aggttgtgaa aagccgcttc gtttcttcat
    20941 actcaaaacg aaacggcttt ttcacaacct cttacttata cttattcaca aaatccaatg
    21001 tctgctggta acaattttgc gattctttta gcgtgtaatc aaattggtat tcatgggtaa
    21061 tctctttttt tgtatctgta taaaacaagg attgcacggg tacctttaat tctgtcaacc
    21121 gattttctaa tgcttgacct tgctcctgga atgagtatgc atttccgtca gttatatacg
    21181 ttggcggaaa ttccttagaa acatggtcag ccacactagc ttctttcaat tgctcactcg
    21241 ttttccaatc ttttgttcca atcaacgacc acgcaacggt tttgacgaaa aacttcataa
    21301 atcgatcatc cgaatgctgc tgtgctgtta gcttcaaatc aacaggtccg caataagaaa
    21361 tggttccttt cagactatct tttggaagta gctgtttgat tttcatttgt ttagcatacg
    21421 catcattcgt ttgtatagct gcatattgca atgcgatttg tgaacctgca ctatctccac
    21481 caaaaaataa ttgttccatg tctagcaatt tgtcgtcttt ttcttcagct aataaatctt
    21541 tgatcagttc attcacttga agaacttgat tagggtattc tgaatcaggc gctaattcat
    21601 aattcatcgc aaccactgcg atgttggcgt ctgaaactaa ttttgtcgca aattctttga
    21661 cacccgattt atctccgccg acgaatcctc caccatgtac ccaaaataga acaggaacag
    21721 gccccttgct gttttttgga tagtagatgt cataagtatt ctctttatac ttggactcat
    21781 acgtcaaatc tgtttttttc gccacgtttt tttctgcttg atcgaacgtt tttttatcag
    21841 tgatttgaac agtatttgaa aacatatggt tgatcaagaa tgctccaggt ctgggggaaa
    21901 gctggaaggc aagaaagatt gcaaacgcga tcccaagaat gattccgaag aaccatccga
    21961 taaatttaag aattttcttt ttcataaggc tccctcagta gttagtatta agcattctga
    22021 ttataccata gtgttatttc ctatcaagct ctcctagatg atttaatgat tttccccaaa
    22081 cttcttctgc aatgcttttg acaaaagaaa ttttttccat tgttcttcaa acaaaacatt
    22141 ttcttcttct gttgaagcaa atccacattg aggacttaag cacaaacgat ccaaaggcag
    22201 atatcgtgtc gcttcgtaga tccggtcaat cacttgctgg tgctcttcca tttcgccatt
    22261 tttcgttaca gtcaaaatct aagacaacta atttatcttc agagactttc tctaaaagaa
    22321 caaaactccc agcacgttca ctatcgtatt ctaaataata ggcacggaca ttttcttgag
    22381 taaaataatg ggtctgctac gtcgtcatcc cccctgatgc cgccaaaatc gaataataat
    22441 ttccgcgtca aacatgtata tttagtgttg aatcatttga gaatatgaaa ataaaaatct
    22501 ttttgatcaa tcagttaatc aaattgaaat aacgaaaaat ctgagacaga atgacgttca
    22561 ttctgaccca gatttgattt tgcacaactc aacagtcctt attggcaaat cgccaaaata
    22621 atgtagacta actaaaa
//
LOCUS       DAZKKZ010000049        22417 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.050, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000049 DAZKKZ010000000
VERSION     DAZKKZ010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22417)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22417)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22417
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.050"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            6..305
                     /locus_tag="ACG8LA_001984"
     CDS             6..305
                     /locus_tag="ACG8LA_001984"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFQ0204278.1"
                     /translation="MKNRLIVACGSGVATSQTIASKIQSMLEDDGIAFPVEAVDYKSI
                     QNELLTAGIYVYVAQPDEEVLEQAKDLGIEVFPGIPFLTGMGVEPIYDSIKELVQ"
     gene            378..1739
                     /locus_tag="ACG8LA_001985"
     CDS             378..1739
                     /locus_tag="ACG8LA_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIC"
                     /protein_id="HFQ0204279.1"
                     /translation="MEVFQTIINYVLNLGSAIFVPLIILILGLLAGMKLKKAFMSALT
                     LGIAFSGMSMVIGYMSNAVSPASEALAKNTGISLPALDLGWTGAASITWSWSYAFIFF
                     AVTIGVNFVLLLFNWTKTLNVDMWNVWGKALTAYLVYYVSGSLAAGFLTAMVQVILEL
                     KLGDMFQKHIQDLTGIPLVTVTHFMTSAAVLLLPFNMIMDKIPALNKRADTNALKKKI
                     GIFSENSVMGFIIGLGLGFAAAYGVSGSLNLAIQTATALSLFPMISKMFMQSLSPLAD
                     AMSEFMKKRFKDREVYIGLDWPILAGRSEIWVTAILLVPVFIGYAIILPGNQVLPLAG
                     IINYSIAVGGLLLTGGNLARMLILGIITMPIYLYGATYLAPILSDLAEKSGAVEGIKK
                     GQLITWSSIEGPEFRVLFAEAFNRNILAIVGCVIFLGLFVLLYKYMIKAKVPSERYAE
                     LQK"
     gene            1761..2021
                     /locus_tag="ACG8LA_001986"
     CDS             1761..2021
                     /locus_tag="ACG8LA_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204280.1"
                     /translation="MKREETDKIKWTVALCGTLLLFLYGLFTQNIIINLLVIFFALVI
                     YKYGNHVLFREYDEKRKRKIEESMKIKEATKEILREKSFIKR"
     gene            2035..2787
                     /locus_tag="ACG8LA_001987"
     CDS             2035..2787
                     /locus_tag="ACG8LA_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HFQ0204281.1"
                     /translation="MSDGRMLFERERQDMARIVRVIFERKNTNVAGGNFSFKTTDDQG
                     KDYIIMTPTMMSEAYLGEISPAQVLVVEPRTRRIVDGVGHLTREINMHEAMYETNPAI
                     KAVLHAHAPNAMFWATTGLPMPNLTEATAKVKEIPVMDFEPNCSEELAELTSDYVKKQ
                     HLELPHMLLLNSHGVLINTGGESGIEAIHKALQILDTVEWNAEIAYKQTIFQALGITD
                     GFYSKGEKIGGLEELKHKTAIYNKSVIAAGGD"
     gene            complement(2881..3486)
                     /locus_tag="ACG8LA_001988"
     CDS             complement(2881..3486)
                     /locus_tag="ACG8LA_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFQ0204282.1"
                     /translation="MTYIFEKGTSGKHLILLHGTGGDEHSLLDIAHFLAPNSTLLSFR
                     GTVQEDGMNRFFKRNGLNQFDLDSLEKETDKLHEKIKEISEKELIPLSDWLLVGYSNG
                     ANIAAHLLLERETELNKGLFFHPMSLGVHQSRSTLEDKTVWISYGDNDPIVSPASFKE
                     LADQFETRQANVTIQLTVTGHQLTMDEIKQAREWTDHLLTK"
     gene            complement(3539..4513)
                     /locus_tag="ACG8LA_001989"
     CDS             complement(3539..4513)
                     /locus_tag="ACG8LA_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ring-cleaving dioxygenase"
                     /protein_id="HFQ0204283.1"
                     /translation="MDTQIRGIHHVTAMTSSATKIYRFFTDILGMRLIKKTVNQDDIE
                     TYHLYFTDDTGAPGTDMTFFDFPNQPKGKKGTDTISRASFRVPSDAALDFWLERFEKY
                     DVTHSAINERFGKKYIEFEDFDNQYYQLISDENNQGVAAGIPWKNSNVPTEFAITGLG
                     PVFVRVSQLEHIRLILEKILGFKETDHSGDFYLFEIGEGGNGASIIIEHRTDLPKAIE
                     GFGNIHHLALRVADKEALEYWIQVINKIELPNSGFVDRFYFQSEYFLAAHHVLFELAT
                     DGPGFLEDEPAESAGEKLSLPPFLEERREAIEAYVRPFDTSDANKKRE"
     gene            complement(4891..5610)
                     /locus_tag="ACG8LA_001990"
     CDS             complement(4891..5610)
                     /locus_tag="ACG8LA_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFQ0204284.1"
                     /translation="MPKYEEIANILRERIRSKEYPLDSFLPNQVDLVKEFGASRMTIK
                     KAINILAMEGLVYSQRGSGTKILNHPFMQKDTSPANEYEGLSLQMKRRHRSLKSQIIH
                     FDVEFPNQYIQERLMIDAEQPVYNIHRLRILDGEPYVLEHTFMPVHLVPGLKKEHLLA
                     SIYDHLHQELNVHFAGAYRAISADKSDEYDQQYLNCAENDPVLEVQQVVYLKDGQPIE
                     YSSSRNRFDVRNYSVLDVRST"
     gene            complement(5737..7008)
                     /gene="celB"
                     /locus_tag="ACG8LA_001991"
     CDS             complement(5737..7008)
                     /gene="celB"
                     /locus_tag="ACG8LA_001991"
                     /EC_number="2.7.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0019191 - cellobiose transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HFQ0204285.1"
                     /translation="MNGFMDKLSEKIMPLANLLGQNRYLTVLRDAFMLSFPLTMFGSI
                     VVVINNLPFFSDATKGTLSNLFGNGQNATMSIMSVFVTFGIGYYLSKSYDVEGIFGGA
                     VSFASFLILTPFAMKTAGGEDVTGVLSLDRLGAKGMFIGMIAAFLAGEIYCRITKRGW
                     QIKMPDGVPPAVTKSFAALIPAVVTLTIFLVINAVMTGIFNANLHDVVYEVIQKPLTG
                     LGSSLPATLIALFFVQFLWFFGLHGQIIVNSVMDPIWNTLMLDNLEAYQHGKELPHII
                     TKPFMETFTVGIGGSGMTLAVVLLMAFVLKKKQYRDVGRLALAPGIFNVNEPAIFGLP
                     IVLNATILIPWVVAPLIVTTFNYLVMAAGLVPAPTGVSVPWTVPIIASGVLATNSWLG
                     GMLQVIDFVIVAFIWYPFLKVLDKQPDLDIA"
     gene            7161..8558
                     /locus_tag="ACG8LA_001992"
     CDS             7161..8558
                     /locus_tag="ACG8LA_001992"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFQ0204286.1"
                     /translation="MKTYTFPENFWWGSAASGPQTEGRVSDDGKGENIWDHWYELEPE
                     KFFDQVGPEKTSQVYTKYKEDVQLMKETGHNTFRTSIQWSHLIPEGTGEINQKAVSFY
                     RDYFTELLDNGIEPFVNLYHFDMPLPLQEKGGWLSRETVDAYVSYAAACFELFGDLVK
                     KWFTHNEPIVPVEGGYLYQFHYPNHINMKEAVQVGYHENLASAKVIKAYHEGGHDGEI
                     GIILNLTPSYPRDETNPEDVKAAKIADAFFNRSFLDPAVKGEFPQELIEIVKELAIMP
                     EIHEGDLELIRENTIDLLGINYYQPRRIKAKETPINHEHSPMPDDYFDNYDMPNKKMN
                     PYRGWEIYEKGIYDILTNTRENYGNIKCYISENGMGVEGEERFVNSEGIIEDDYRIEF
                     VTDHLKYVHQAIQEGTNCVGYHMWTCMDNWSWTNAYKNRYGFIAVDLAQDGKRTIKKS
                     GRWFKTVSEKNGFDA"
     gene            8639..9079
                     /locus_tag="ACG8LA_001993"
     CDS             8639..9079
                     /locus_tag="ACG8LA_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HFQ0204287.1"
                     /translation="MVDTYRNILVAIDGSEKAEKAFLEAITIAKRNQATLHILYVNEV
                     TGNYFGDFAFVTTSLQEELDEVAENQMKEHRNLAIEKGLTDIETYVLYGYPKTLIANF
                     HESKEPIDLIVMGATGLNAVERALVGSTTSYVVNHASCNVMVVK"
     gene            9227..9553
                     /locus_tag="ACG8LA_001994"
     CDS             9227..9553
                     /locus_tag="ACG8LA_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HFQ0204288.1"
                     /translation="MISSDGIRGYNDAIILSILNKNDSYGYEISKTIRERTNDSYVIK
                     ETTLYSVFARLEKNQLIVSYPGEVTHGKKRTYYKITEIGRNLLEEKKQEWLTTKDVVD
                     QFLEGN"
     gene            9554..10303
                     /locus_tag="ACG8LA_001995"
     CDS             9554..10303
                     /locus_tag="ACG8LA_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease prefix domain 1-containing protein"
                     /protein_id="HFQ0204289.1"
                     /translation="MDTIRNYLDSLFIGVPQSTEIDKLKTDLLANMEDHYHELMGEGK
                     NEQEAIGTVISTFGSIDELLEELDVEKKHQADETETNTASIYLSEAENYWKEYRAASL
                     QVASGVLFISLSFASFLFFCSAGYVFMGISCLIFGIALAVGFFIASGMKITRLNHFLH
                     HRKIPEKVLAEAKEKEEEYQRSFGFSLIAGIGLCIFSLFPLLASLMWYMDGSIGASIF
                     FVTVGTGVFLIIYGSLVRHSYRQFTQSAYYW"
     gene            complement(10383..10838)
                     /locus_tag="ACG8LA_001996"
     CDS             complement(10383..10838)
                     /locus_tag="ACG8LA_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HFQ0204290.1"
                     /translation="MLTIYSSRTHSYHLMANWLKDHQMPYRERIFTPKQPLTRKEIFY
                     LLSLTENGFDDLLAKRSIDYKNLKDQIDQCTTSELVDLIVSHFTLLQRPIITDGKKLL
                     VGFNEDSMRLFIPVQWRRSQLKSVYNDFTWVSNLENSTDLDDEFLNYYI"
     gene            complement(11265..11540)
                     /locus_tag="ACG8LA_001997"
     CDS             complement(11265..11540)
                     /locus_tag="ACG8LA_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204291.1"
                     /translation="MKLEDKKVILKKIKRLPDQIDGYTICSFKKDRSIKAYTQNTEKG
                     IIYFLHEEGYDTQTFMFTEKKEFHKQMKKLIEKEFPRSHKLYVNQQF"
     gene            11834..12649
                     /gene="thiD"
                     /locus_tag="ACG8LA_001998"
     CDS             11834..12649
                     /gene="thiD"
                     /locus_tag="ACG8LA_001998"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008902 - hydroxymethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0008972 - phosphomethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HFQ0204292.1"
                     /translation="MEDQYVQAMTIAGSDSDGSAGMQADMHTFFTRNVYGVSVMTACV
                     AGNSYGIGASVTLPTDFIDKEFELIAKDFQIRAAKTGMLADSKLIETVVKNYQKYDFG
                     PLVVDPVIVTKHGNLLLEESALQSLKEKLVPLAEVLTPNFYEAEKLTGRTLAAEEDFV
                     QAAKELQDMGAKNVMIKGHHAKNAQQETVNDYVLFESGKSFWLNAPFYPTDRINGTGD
                     SLSACIAAELAKGKTVEQAIRLAKDYVNRAIREEINVGHKYGPINHWAAGELE"
     gene            complement(12978..14429)
                     /gene="cls"
                     /locus_tag="ACG8LA_001999"
     CDS             complement(12978..14429)
                     /gene="cls"
                     /locus_tag="ACG8LA_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008808 - cardiolipin synthase activity
                     [Evidence IEA];
                     GO_function: GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA];
                     GO_process: GO:0032049 - cardiolipin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HFQ0204293.1"
                     /translation="MVSSIITALYLLNALIALVAILIKPRDVAAIWAWLLVLFALPGV
                     GFVLYLFFGRGLTDKKKFYLRQSDLKELENFQSFRGDTIEHYDPDMGDKDKQQFVDFF
                     SSLNRMPLTRMNSVTLLTDGQEKLDSLLQDLKKAKHSIHIEYYAFVTDNIGQQVLHVL
                     EEKAAEGVEVRILYDAFGSHGTKAKDFNRLIKNGGHVHTFVTSQRALLRFRLNYHDHR
                     KIVVIDGKISYTGGFNIANQYVNTTKKFGYWRDTHIRIFGAASSLLQLRFLTDWNVSV
                     PEEKKVGYHLNYFFKKADRDESKLADTSIQLVSSGPNNEREQIKLSFIKLITSAKKRV
                     WIQTPYLVPDESVIAALKIATASGVDVKIMIPNKPDHPFIYRATQYYARQLIKENVQI
                     LVYENGFLHAKTLIMDDEICMVGSANQDIRSYRLNFETSAVIYDPEFLEELATQFKED
                     ETHCSSMTTETVKEMSNWLLFKQQISRLFSPIL"
     gene            14770..17436
                     /locus_tag="ACG8LA_002000"
     CDS             14770..17436
                     /locus_tag="ACG8LA_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HFQ0204294.1"
                     /translation="MENKEQAQQAVYKETIDSLMQQTQSSTDGLSTTQAKEKLERDGL
                     NQLKEKPKKPTWKLFLETFKDAMVIVLLIVALIQMVMGDYIEFLVIFAVLMLNSIISV
                     VQTKKAEGSLEALKNLSAPDARVIRDGKEKTIPANELVVGDIVLLDAGDYVPADGRLL
                     DAGSLKVDEGMLTGESTSAEKEVTDITSTVPIGDRTNMVFSGTIVTYGRGKFLVTSTG
                     NNTEIGQVAGLLESTTEQVTPLQRGLDKFSKKLSLAILALSLLILGIQLFRIYLGEGT
                     GDMTADIVSAVMFAVAVAVAAIPEALQSIVTIVLSLGTNKMAKRHAIIRKLPAVETLG
                     STSIICTDKTGTLTQNKMTVVDYFLGNGDTGDFTNDPSKWTADERRLIEISVLANDAS
                     ISEDGTKLGDPTEVAFIDFSEKLNQPYQEIRNNYPRQAELPFDSDRKLMSTGHTIDNK
                     NYLFVKGGPDIVFQRSKKVLLNGEVVPMTDELMKKFQEQNEAFSTRALRVLAFAYRPL
                     DNFDLSFEDEDDLILVGLLAMIDPPRAEVTQAVTEARSAGIKTIMITGDHKTTAVAIA
                     KQIGIFEEGNLALTGTELDELTEDQLNEVLEKVTVYARVSPENKIRIVRAWQNKGHIS
                     AMTGDGVNDAPALKQADIGIAMGTGTDVAKDAAAMVLTDDNFASIVSAVEVGRNVFDN
                     IKKAISYLFAGNLGAIIAIIFALVADWSNPFTALQLLFINLVNDSLPAIALGTEKAEP
                     ATMNRPPRDPNSGIFTDKTLISVTYRGVLIGIAVIFAQWLGMQHSPEFGVAMSFSTLI
                     WCRTLQTFPARSNTQTAIQAGFFSNRSVLLAVVVCSALYCLTMIPGLKEVFSIPSAFG
                     LTEVFTCMGIALVTIVLMEITKLIIVRVQGNK"
     gene            17800..18552
                     /locus_tag="ACG8LA_002001"
     CDS             17800..18552
                     /locus_tag="ACG8LA_002001"
                     /EC_number="2.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFQ0204295.1"
                     /translation="MNEKEWDEFAEEYYEIQQESQVTIAEDVKNYLKTEKVLPAETAA
                     DVAGGSGRFLSLAKEINRYDLIDFSSGMLENAKKEAEKNELPNVSFIKQSLEEFIQSN
                     ETYEMVFTAANPALVHLIQLEKLMKKSSKWCVIIRVVESIDDVFYPIEKQLGMIEEDP
                     NTSPVVMDQFETYLIDEGFKVKKKDFTYFTQESITEELMKLYYDAYAKDPVVTRYIRK
                     LFSEKREILSTTKLTYRLLLWSADKKRTFHDS"
     gene            complement(18574..19728)
                     /locus_tag="ACG8LA_002002"
     CDS             complement(18574..19728)
                     /locus_tag="ACG8LA_002002"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004421 - hydroxymethylglutaryl-CoA
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HFQ0204296.1"
                     /translation="MKIGIDRLSFFIPNLYLDMTELAESRGDDPAKYHIGIGQDQMAV
                     NRANEDIITLGANAASKIVTEKDRELIDMVIVGTESGIDHSKASAVIIHHLLKIQSFA
                     RSFEVKEACYGGTAALHMAKEYVKNHPERKVLVIASDIARYSLASGGEVTQGVGAVAM
                     MITQNPRILSIEDDSVFLTEDIYDFWRPDYSEFPVVDGPLSNSTYIESFQKVWNRHKE
                     LSGRGLEDYQAIAFHIPYTKMGKKALQSVLDQTDEENQERLMARYEESIRYSRRIGNL
                     YTGSLYLGLTSLLENSKSLQPGDRIGLFSYGSGAVSEFFTGYLEENYQEYLFAQSHQE
                     MLDSRTRITVDEYETIFSETLPEHGECAEYTSDVPFSITKIENDIRYYKI"
     gene            19913..22354
                     /locus_tag="ACG8LA_002003"
     CDS             19913..22354
                     /locus_tag="ACG8LA_002003"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004420 - hydroxymethylglutaryl-CoA
                     reductase (NADPH) activity [Evidence IEA];
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_process: GO:0015936 - coenzyme A metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HFQ0204297.1"
                     /translation="MKEVVMIDAARTPIGKYRGSLSPFTAVELGTLVTKGLLDKTKLK
                     KDKIDQVIFGNVLQAGNGQNVARQIALNSGLPVDVPAMTINEVCGSGMKAVILARQLI
                     QLGEAELVIAGGTESMSQAPMLKQYQSETNEYGEPISSMVNDGLTDAFSNAHMGLTAE
                     NVATQFSVSREEQDRYALSSQLKAAHAVEAGVFSEEIIPVKISDEDVLSEDEAVRGNS
                     TLEKLGTLRTVFSEEGTVTAGNASPLNDGASVVILASKEYAENNNLPYLATIKEVAEV
                     GIDPSIMGIAPIKAIQKLTDRSGMNLSTIDLFEINEAFAASSIVVSQELQLDEEKVNI
                     YGGAIALGHPIGASGARILTTLAYGLLREQKRYGIASLCIGGGLGLAVLLEANMEQTH
                     KDVQKKKFYQLTPSERRSQLIEKNVLTQETALIFQEQTLSEELSDHMIENQVSEVEIP
                     MGIAQNFQINGKKKWIPMATEEPSVIAAASNGAKICGNICAETPQRLMRGQIVLSGKS
                     EYQAVINAVNHRKEELILCANESYPSIVKRGGGVQDISTREFMGSFHAYLSIDFLVDV
                     KDAMGANMINSILESVANKLREWFPEEEILFSILSNFATESLASACCEIPFERLGRNK
                     EIGEQIAKKIQQAGEYAKLDPYRAATHNKGIMNGIEAVVAATGNDTRAVSASIHAYAA
                     RNGLYQGLTDWQIKGDKLVGKLTVPLAVATVGGASNILPKAKASLAMLDIDSAKELAQ
                     VIAAVGLAQNLAALRALVTEGIQKGHMGLQARSLAISIGAIGEEIEQVAKKLREAEKM
                     NQQTAIQILEKIREK"
BASE COUNT         7198 a         3932 c         4673 g         6614 t
ORIGIN      
        1 aaaaaatgaa aaatcggtta attgtcgcat gtggaagtgg agtagcaacg agtcagacaa
       61 tcgctagtaa gatccaaagt atgttagaag atgacggcat cgcatttcct gtagaagcag
      121 ttgattacaa atcgattcaa aatgagcttc taactgctgg aatctatgtg tatgtcgcac
      181 aacctgatga ggaagtactt gaacaagcaa aagatttggg tattgaagta tttccaggaa
      241 ttccattttt aactggaatg ggtgtagaac ctatttatga cagtatcaaa gagttagtac
      301 agtaaaggag gattgttgga taaaaaagtt ggttcatagt tttatttact atatttagaa
      361 agaaagaagg tttatttatg gaagttttcc aaaccattat caattatgtt ttgaacttag
      421 gatcagccat ttttgttccc ctgattattt tgatacttgg attgttggca gggatgaaat
      481 taaaaaaagc attcatgtct gctttgactt tagggattgc ttttagcgga atgtctatgg
      541 tcattggcta tatgtctaac gcagtaagtc cagcatcaga agcattggct aaaaatacgg
      601 gaatcagttt gcctgcactt gatcttgggt ggacaggtgc agcaagcatc acatggtcgt
      661 ggagttatgc ttttatattt tttgcagtaa cgattggggt caattttgta ctgttacttt
      721 ttaattggac gaagacgtta aatgttgata tgtggaatgt ttgggggaaa gctttaactg
      781 cttatttagt ttattatgtt tccggtagtt tggctgcagg ctttcttact gcaatggtcc
      841 aagttatatt ggaattaaag cttggtgata tgtttcaaaa acatatacaa gatctcacag
      901 ggattccatt agtaacagtg actcatttta tgacatctgc cgctgtcttg ttgctgcctt
      961 tcaatatgat catggataaa attcctgctt taaataaacg agcggatacg aatgcattga
     1021 agaagaaaat tgggatcttc tctgaaaact ctgtaatggg attcattatt ggattggggc
     1081 ttggctttgc tgctgcgtat ggcgtttcag gttctcttaa tctagcgatc caaacagcta
     1141 cagcattaag tttgtttcct atgatctcta aaatgttcat gcaatctttg tctcctctag
     1201 cagacgctat gtcagaattt atgaaaaagc ggtttaagga tcgtgaagta tatatcggat
     1261 tggactggcc gatattagct ggtcgttcag aaatttgggt tactgctatt ttacttgttc
     1321 ctgtgtttat tggttatgcc attattttgc caggaaacca agtattgcca ttagcaggga
     1381 ttatcaacta ttcgattgcg gtcggcggat tacttttaac aggaggaaac ttggctcgta
     1441 tgctgatctt gggaatcatc actatgccta tttatttgta cggggccact taccttgcgc
     1501 caatactcag tgatttagca gaaaaaagcg gagcagtcga gggaatcaag aaaggacagt
     1561 tgatcacatg gtcatccata gaagggccgg agttcagggt tttatttgcg gaggcattta
     1621 ataggaatat tctcgctatt gtaggatgcg tgatttttct aggactgttt gttctacttt
     1681 ataaatatat gataaaagcg aaagtaccga gtgaacgtta tgctgaacta caaaaatagc
     1741 attgaaatgg tgggaaagta atgaaaagag aagagacaga taaaataaaa tggacagtcg
     1801 ctctttgtgg tacacttctg ctatttctat atggactctt tactcagaat atcatcatca
     1861 atctattggt catttttttc gcactagtga tctataaata tggaaatcac gttttattca
     1921 gagagtacga tgaaaaaaga aaacggaaaa tagaagaatc aatgaaaata aaagaagcta
     1981 ccaaagaaat attgagagaa aaaagtttta taaaaagata atggaggggt cattatgtca
     2041 gatggacgta tgttatttga gagagaacga caggacatgg cacgtatcgt aagagtgatt
     2101 ttcgaaagga aaaacacaaa tgtcgcagga gggaattttt cctttaaaac cactgatgat
     2161 caagggaaag actacatcat catgacgccg accatgatgt cagaagccta tctaggagag
     2221 atttctcctg cacaggttct agtagtagaa ccaagaacgc gtagaatcgt tgacggagtc
     2281 ggtcatttaa ctcgtgaaat caatatgcat gaagcgatgt atgagactaa tccagctatc
     2341 aaagctgtcc tacatgctca tgcgcctaat gcaatgttct gggcgactac tgggttgcct
     2401 atgcctaatt tgacagaagc cacagctaaa gtaaaagaga ttcctgtcat ggactttgag
     2461 cctaattgct ctgaagaact tgctgaattg acaagcgact atgtaaaaaa acagcatctc
     2521 gaattaccgc atatgttgct gctcaactct catggcgtat tgatcaacac aggtggagaa
     2581 tcaggaatcg aagctatcca taaagcactg caaatccttg atacagttga atggaatgca
     2641 gaaattgcct acaagcagac gatttttcaa gcattaggga ttactgacgg tttttattca
     2701 aaaggtgaga aaatcggggg attggaagag ttgaaacata aaacggctat ttataataaa
     2761 tctgttattg cagctggtgg agactaacct atctgacaca aaaaactacg actttcacaa
     2821 aatctgatcc agatcgatat ctgcttcagg ttgtattatg taagtcgtag ttcttttctt
     2881 ttatttagtt aagaggtggt ctgtccattc cctcgcttgc ttgatttcgt ccatcgtcaa
     2941 ctgatgacct gttacagtta gctgaatagt cacatttgct tggcgtgttt cgaattgatc
     3001 ggccaattct ttaaaggaag caggggaaac gattggatcg ttatcaccat aagaaatcca
     3061 gacggtttta tcctctaatg tggaacggct ttgatgaaca cctagagaca tcggatggaa
     3121 aaacaaccct ttatttagct cggtctcacg ctccaataat aaatgagcag cgatgtttgc
     3181 gccatttgaa tagccgacaa gcagccagtc acttaacggt atcagttctt tttcgctgat
     3241 ttctttgatt ttttcatgga gtttatctgt ttctttttcc aaactgtcca ggtcgaattg
     3301 attcaatcca ttacgcttga aaaaacgatt catcccatct tcttggaccg tgccacgaaa
     3361 agaaagcaat gtactgtttg gtgcaagaaa gtgagcgata tccagtaaag aatgttcatc
     3421 gccacctgtg ccatgaagta agatcaaatg cttgccactt gttccttttt caaaaatgta
     3481 ggtcattttg ttccctcttt tctgtttcta tagatgcaaa tgaagtagca tgaagagatt
     3541 attcacgttt tttatttgca tcacttgtat cgaaaggacg gacataagct tcaatggctt
     3601 cacgacgttc ttctaagaat ggaggaagag atagtttttc tcctgctgat tctgctggtt
     3661 catcttcaag gaatccagga ccatcagttg ctaattcaaa cagtacgtga tgagcggcta
     3721 ggaagtactc agattggaaa tagaaacgat cgacgaaacc agaatttggc aattcaatct
     3781 tattgattac ttgaatccag tattccaatg cttctttgtc tgctacacgc aatgctaagt
     3841 gatggatatt tccaaatcct tcgattgctt ttggcaagtc tgtccgatgt tcaataatga
     3901 tgcttgcacc atttccccct tcaccgattt caaataagta gaaatctcct gaatggtctg
     3961 tttctttgaa tcctaagatt ttttcaagaa tcaagcggat atgctctaat tgactgacac
     4021 ggacaaagac aggtccaagt cctgtgatcg caaactctgt cggtacattg ctgtttttcc
     4081 aaggaatgcc agctgctaca ccttgattgt tttcgtcaga gatcaattga taatactgat
     4141 tatcgaaatc ttcaaattcg atatattttt tgccgaaacg ttcattgatt gctgaatgag
     4201 taacgtcata tttttcaaaa cgttccaacc aaaagtctaa tgctgcgtca cttggcacac
     4261 ggaaagaagc acgagagatc gtatctgttc ctttttttcc ttttggctga tttggaaaat
     4321 caaagaaagt catatctgtt cctggcgcac cagtatcgtc tgtaaagtaa agatggtaag
     4381 tttcgatgtc atcttggtta actgtttttt tgattaagcg cattcctaaa atatctgtaa
     4441 aaaagcggta gatttttgta gcgctagatg tcattgctgt gacgtggtga attcctctga
     4501 tttgtgtatc catgataaat ttcctcctgt taacttacaa aaagtaagta gttgatttag
     4561 acatagtata gagggtgcat ctctattttg caattaattt gtcttctaaa gtatcaggaa
     4621 ggaatcaaga atggaaaaga ggagggacgg atcaataaaa taaaaagact tacgactagc
     4681 tgtatcgatt tcaaaaaaac tagctttaaa aagctaactt tagaatcatt acgggtggtc
     4741 ataagtcttt ttatgctgag ttattttttc atttttgagc taatgcttag gatagaatag
     4801 aatgttgatt tcacgatctc ttcttgttac ttgaaactgc ttaccactgt cacgatctct
     4861 tggtaaacgg ctttttcaca acctctttgg ttaagttgaa cgcacatcca gcacagaata
     4921 gttccgaaca tcaaatcggt ttcggctgga agaatattca atcggctgtc catctttgag
     4981 atagacgact tgctgaactt ccagtacagg atcgttttct gcacagttca aatattgctg
     5041 atcatattca tcacttttat ctgcagaaat agcacgataa gcccctgcaa aatggacatt
     5101 caattcttga tgaagatgat catagataga ggctaacaaa tgttcttttt ttaaacccgg
     5161 cacaagatgg actggcataa aggtatgctc taaaacatat ggctcgccat ctaagatcct
     5221 taaccggtga atattgtaga caggttgctc ggcatcgatc atcaatcgtt cttggatata
     5281 ttgattaggg aattcaacat caaaatgaat gatttgactc ttcaaagaac gatgtctgcg
     5341 tttcatttgg agactcaaac cttcatactc gttagcgggc gatgtgtctt tttgcataaa
     5401 tggatgattc aagattttcg ttcctgatcc tcgctgcgaa tagacaagtc cttccattgc
     5461 taagatattg atggcttttt tgattgtcat ccggctcgca ccaaattctt ttaccaagtc
     5521 gacttgatta ggcaaaaaac tatcgagagg atactctttt gaacggatac gttctcttaa
     5581 aatatttgcg atttcttcgt attttggcac gttattcacc tcttctagag tataacgaaa
     5641 gattatgctt ccgacaactc gaagtagcat ctggaacatt gtttattcga aaaaagaggt
     5701 catgacaagt ttttgtcaca accccttaat gatctattaa gcaatatcta aatctggttg
     5761 tttatctagt actttcagga atgggtacca gataaaggca acgatgacaa agtcgatgac
     5821 ttgcagcata ccaccaagcc atgaatttgt tgctaagaca ccgcttgcaa tgattggcac
     5881 agtccatgga acagagacgc cagttggtgc agggacaagt ccagcagcca ttaccaaata
     5941 attgaacgtc gttacgatta gaggtgccac aacccaagga ataaggattg ttgcattcaa
     6001 tacgatcggt agaccgaaga tcgctggttc atttacattg aaaataccag gtgctaaagc
     6061 taatcgtcca acatcacgat actgtttctt tttaagaaca aaggccatca ataaaacgac
     6121 agctaaagtc attccagagc caccaatacc aacagtgaag gtttccatga atggttttgt
     6181 gatgatgtgt ggtaattctt ttccatgttg ataagcttct aagttatcaa gcatcagtgt
     6241 attccaaatc gggtccatta cagagttgac gatgatttgt ccgtgaagtc cgaagaacca
     6301 taagaattgg acaaagaaca aagcaatcaa tgttgcaggt aaactacttc ccaaaccagt
     6361 taatggtttt tggatcactt cataaacgac gtcatgtaag ttagcattga aaataccagt
     6421 catcacagca ttgattacta agaaaatagt tagtgtcact acagcaggga tcaaagcggc
     6481 aaatgatttt gttactgcag gcggaactcc atcaggcatt ttgatctgcc agccgcgttt
     6541 cgtgattctg cagtagattt ctccagccaa gaaagcagcg atcattccaa tgaacattcc
     6601 ttttgcgcca agacgatcaa gtgaaagcac accagtcaca tcttcaccgc cagcggtttt
     6661 cattgcaaaa ggcgtaagaa tcaagaagct ggcaaaagac acggcaccac cgaaaatacc
     6721 ttcaacgtca taagattttg ataaataata gccgatacca aaagtaacaa aaaccgacat
     6781 gatgctcatt gttgcatttt gcccattacc gaataaattc gataaagttc cctttgttgc
     6841 gtcactgaaa aaaggcaagt tattgataac gacaacgatc gaaccgaaca tcgttaaagg
     6901 gaaggaaagc atgaaagcat cccgcagcac tgtaaggtaa cgattttgcc ctaataaatt
     6961 agctaagggc atgattttct cagaaagctt gtccataaaa ccgttcattt ttattcacct
     7021 caaatttatt tgcaatcgat tacatacaaa gtataacgcc aaaaatttta aatgtctagt
     7081 cattttcata aaaagtattg atttattttt tagggttcgt tatgattacg gtatcaagaa
     7141 aaaagagagg aagtaaaaaa atgaaaacct acacattccc agaaaatttt tggtggggtt
     7201 ctgctgctag cggaccgcaa acagaaggaa gagtaagtga tgatggtaaa ggagaaaata
     7261 tttgggatca ttggtatgaa ttagagcctg aaaaattctt cgatcaagta ggacctgaaa
     7321 aaacttcgca agtttacaca aaatacaaag aagatgttca gttaatgaaa gaaactggcc
     7381 ataacacatt tcgtacatct atccaatgga gtcatttgat tccagaaggg acaggtgaaa
     7441 tcaatcaaaa agctgtttct ttttatcgag attattttac tgaattgctg gataatggta
     7501 ttgaaccttt tgtgaacctt taccatttcg atatgccact accactgcaa gaaaaaggcg
     7561 gatggttatc aagagaaacg gtcgacgctt atgtttctta tgcagcagcg tgctttgaac
     7621 tgtttggaga tctggtcaaa aaatggttta ctcataatga accaatcgta cctgtagaag
     7681 gaggctactt gtatcaattc cactatccaa atcatatcaa tatgaaagaa gcggtccaag
     7741 taggctatca tgagaatcta gcaagcgcaa aggtaatcaa agcctaccat gaaggcggac
     7801 atgatggtga gatcggaatc atcttgaatc tgacaccaag ctatccgaga gatgaaacga
     7861 acccagaaga tgtaaaagcg gcgaagatcg ctgacgcatt cttcaaccga tcattccttg
     7921 accctgcagt gaaaggagag tttccacaag agttgatcga aattgtcaaa gaattggcta
     7981 taatgccaga gatccatgaa ggagacctag aactcatccg tgaaaacacg attgacctgc
     8041 taggaatcaa ttactatcag cctcgtcgaa tcaaagcaaa agaaactcca atcaatcacg
     8101 aacatagccc catgccagat gattattttg ataattacga catgcccaat aaaaaaatga
     8161 atccatatcg tggatgggaa atttacgaaa aaggaatcta tgatatttta acgaatacaa
     8221 gagaaaacta tggtaatatc aaatgctata tttctgaaaa tgggatgggg gtcgaaggag
     8281 aagaacgatt tgttaacagc gaaggaatta ttgaagatga ttaccggatc gagtttgtta
     8341 cggatcattt gaaatacgtc catcaagcaa tccaagaagg aaccaattgt gtgggttacc
     8401 acatgtggac atgtatggac aactggtctt ggacaaatgc ttataagaat cgctatggct
     8461 ttatcgctgt tgatttggca caagacggta aacggacgat caaaaaatca ggtcgctggt
     8521 ttaaaacggt ctctgaaaaa aacggatttg atgcctgata ttttttgata aaacgttcac
     8581 aaaatgtttg ttctaacact gtaatcgtgc tacactaaca gtgaaggagg cgtttacaat
     8641 ggtagatact tatcgtaata ttttagtagc aattgatggt tctgaaaagg cagaaaaagc
     8701 atttcttgag gcaatcacga ttgccaaacg aaatcaggca acgttgcaca tcctgtatgt
     8761 caatgaagta acaggcaatt actttggtga ttttgcattt gttacaacaa gccttcagga
     8821 agaattggat gaggttgcgg aaaaccagat gaaagaacat cgaaacttgg caattgaaaa
     8881 aggcctgaca gatatcgaga catatgttct ttacggttat ccaaagacac tgattgctaa
     8941 tttccatgaa tcgaaagaac caatcgatct gattgtcatg ggggcgacag gtctgaatgc
     9001 ggtagaacgt gcactagtag gttccactac ttcctatgta gtcaaccacg catcatgtaa
     9061 cgtcatggtt gtaaaataaa taaattaagg gaacagaaag caaaaaagca taacgcttct
     9121 tttgctttct gttcctttta tttttttgta aaaaattact ttacctgatg aagtaatcat
     9181 gctattctaa ttacaacgac agatggagta atatggagga aagaaaatga tttcaagtga
     9241 tggaatacgc ggatacaatg atgcgattat tttatcgatc cttaacaaaa acgattctta
     9301 tggatatgaa atttctaaaa cgattcgtga gaggacaaat gattcctatg tgatcaaaga
     9361 gacaacactt tactccgttt ttgcccgttt agaaaagaat caactgattg tttcgtatcc
     9421 tggagaagtg actcatggaa aaaagcggac atattataaa atcactgaaa tagggcgtaa
     9481 tcttttagaa gaaaaaaagc aagagtggct gacgacgaaa gacgtagtcg atcaattttt
     9541 ggagggaaat taaatggata caatccgtaa ttatttagac agtcttttta tcggagtacc
     9601 tcaaagtacc gagatagata agctgaaaac tgatttgttg gcaaatatgg aagaccatta
     9661 tcatgaattg atgggagaag gaaaaaatga acaggaggcc atcggtacag taatttcgac
     9721 atttggttca atcgatgaat tattagaaga actagatgtc gaaaaaaaac atcaagctga
     9781 cgagacggaa acaaacacag cttctattta tttaagcgaa gcagaaaact actggaaaga
     9841 atacagagcg gcaagtctcc aagtggcatc aggtgttcta ttcattagct tatcttttgc
     9901 aagttttctt ttcttttgtt cagcaggata tgtgttcatg ggtatttctt gtctgatttt
     9961 cggtatagca ttagctgtcg gtttttttat tgcttctggt atgaaaatca cacgtttaaa
    10021 tcactttttg caccatcgga aaatacctga aaaagtatta gcagaagcaa aagaaaaaga
    10081 agaagagtat cagcgaagtt ttggcttctc actgattgca ggaattggat tatgtatttt
    10141 ttcacttttc ccacttttgg cttctttaat gtggtatatg gatggtagta tcggtgcctc
    10201 tatatttttt gttacggtag gaacgggtgt cttcttgatc atttatggca gtctagtccg
    10261 tcattcttat cgtcaattca ctcaaagcgc ttattactgg tgaatgtatt cagatttgta
    10321 aaaatattct atttatccgg cgtagaaaaa aagactgtga cacgcttttg tcacagtctt
    10381 ttttatatat aataatttaa aaattcatca tctaaatccg tagaattttc tagattgctt
    10441 acccatgtaa aatcgttata gacagatttc agttgacttc tgcgccattg tacagggata
    10501 aaaagacgca tgctatcttc attgaatccg actaataatt tctttccgtc agtaatgatg
    10561 ggacgttgta acaaagtaaa atgcgagacg atcagatcga caagctctga ggtcgtacat
    10621 tggtcgattt ggtctttcaa atttttataa tcaatcgagc gtttagctaa tagatcgtca
    10681 aatccgtttt ctgttaatga caataaataa aatatctctt tccttgttaa aggctgttta
    10741 ggtgtgaaaa ttcgttctct gtaaggcatt tgatggtctt tcagccagtt tgccatcaga
    10801 tggtaactat gtgtgcgaga agaatagatc gtaagcataa aaaaactcct taaatagtcc
    10861 attaatttgt tagatctgtt gagataaata ataggtaagg agctgtgcat aagcattgat
    10921 caaaacaacc caaacatcat tagaaataac tttctaaagt cttaaacttg cgacgagaag
    10981 caactagact aatagaaaaa atgtcttagc catttggctt cctgtttgtt tttttgctta
    11041 tgctgcagct cctcgggaaa gggttctaac aatttgaaga aggttgatga ttgatctagt
    11101 ttaaattgtg tgaaatttga aatctggtgt ttttactaga tgaatcacct aacaactatg
    11161 attataactt atagaacttc tgttttgcat tcggttttgt tatagttgtt ataaagtttt
    11221 attttattac agaacatttt taattaataa agaacagtta gaagttaaaa ttgctgattc
    11281 acatagagtt tatgacttct tggaaattct ttttcaatca gttttttcat ctgtttatga
    11341 aattcttttt tttcagtaaa cataaaggtt tgggtatcgt aaccttcttc atgtaggaaa
    11401 tagattattc ctttttctgt gttttgcgta taagctttta tactcctgtc ttttttgaaa
    11461 gaacagatcg tatagccatc tatttggtct ggtagtcgtt tgattttctt caaaatgact
    11521 tttttatcct caagtttcat ttttttcacc tgactttatt tttttcatat ggaaatcata
    11581 gcgcctttgg ttatatgaaa acaagaagga tactgaaata tatataaatc aaatagtggt
    11641 tatttattat tagaatagcg aatacaaata aacgaccact attttctgat ttattgcaaa
    11701 tgttttttca aataaatttg attaccaaga aaaggtagtg gtatatttac tgagggatac
    11761 tttgaaaaac atatgataga aacagtaaca gtattatgaa aaatcttttt ataaaaatgg
    11821 aggaatcgat ttgatggaag atcagtatgt acaagcaatg acgatcgcag gatcagatag
    11881 cgatggaagc gcagggatgc aagcagatat gcatacattc tttacaagaa atgtttacgg
    11941 tgtttctgtc atgaccgcat gtgttgcagg taattcttac ggaatcggag caagtgtgac
    12001 attgccaaca gattttatcg acaaagaatt tgaactgatt gcgaaggact ttcaaatacg
    12061 tgcagctaaa acaggtatgc tagcagattc aaagttgatt gagacagttg taaaaaatta
    12121 ccaaaaatat gattttggac cattagtcgt ggatcccgta atcgtaacga aacatggaaa
    12181 tcttttacta gaagaatctg ctttgcaaag cttgaaagaa aagcttgtcc ctttggccga
    12241 agtactgaca cctaattttt atgaagcaga aaagctgact ggacggacat tagcagctga
    12301 agaagatttt gtgcaagcag caaaagaact gcaagatatg ggtgcaaaaa acgttatgat
    12361 caaaggacat catgctaaaa atgcgcagca agaaacagtc aatgactacg tattgttcga
    12421 atcaggaaaa tcattttggt taaatgcacc attttatcct accgaccgga tcaacggaac
    12481 tggcgattcg ctatctgcat gtattgcagc tgagttagcg aaaggaaaaa cagttgaaca
    12541 agcgatccga ttggcaaaag actatgtaaa ccgtgcaatt cgtgaagaaa taaatgtagg
    12601 gcacaaatat ggccccatca atcattgggc agctggtgaa ttagagtaaa agaaagaagt
    12661 tgtgaaaaag ttgccctgca tcaagtaata agaacagcca agtaaaaaca gcttcttatg
    12721 tttttaactt ggttggactt attaccgcag atgcaagctt ttgaacaccg tttaagaaag
    12781 aggtcgtgag cctgccgtcc agctccgagt cacaaggaac aagttcaaaa aacagcttct
    12841 catgtttgtt gaatattgtg acttgtgacc gaggagttgg caggagaaca ccgtttgttc
    12901 ggaagaaggg actgtgacaa gatttttgtc acagtccctt taatcttagt atatttttct
    12961 ctacttgaat aaaaaaatta taggattgga gaaaataatc gagaaatttg ttgcttgaat
    13021 aatagccagt tagacatttc cttgactgtt tcagttgtca tggatgaaca atgtgtctca
    13081 tcttctttga actgagtagc aagttcttct aaaaactcag gatcgtaaat gacagcactt
    13141 gtttcaaaat tcaatcggta gctacgaata tcttgatttg ctgaacctac catgcagatt
    13201 tcatcatcca ttatcaatgt ttttgcatgg aggaagccgt tctcatagac aaggatttgt
    13261 acattttcct tgatcagctg ccgagcataa tattgtgttg ctcgataaat aaaaggatga
    13321 tccggtttgt tgggaatcat gattttcaca tctacaccag aggcagttgc gatttttaaa
    13381 gcagcaatga cactttcatc aggaacaagg taaggtgtct gtatccaaac acgtttttta
    13441 gcagaagtaa tcaatttgat aaatgaaagc ttgatttgtt ccctttcgtt attcggtccg
    13501 cttgaaacaa gctggatgga tgtatcagca agcttagatt catctcgatc tgctttttta
    13561 aagaaataat tcaaatgata gccgaccttt ttttcttcag gtaccgagac gttccagtct
    13621 gttaagaagc gaagctggag caaagaagaa gcggcaccga aaatccgtat atgcgtatcg
    13681 cgccaatagc cgaatttttt tgttgtattt acatattgat tggcaatatt gaaaccaccg
    13741 gtataactaa tctttccatc gatcacaacg atttttcggt gatcatggta attcaatcgg
    13801 aaacgaagta atgccctttg tgaggtaaca aatgtatgga catgtccacc atttttgatt
    13861 agacgattga aatcttttgc ttttgtgcca tgagagccaa atgcatcata taatattcga
    13921 acttccacgc cttctgcggc tttttcttct aaaacatgta agacttgctg gccgatatta
    13981 tctgtcacaa atgcgtaata ttcgatatgg atcgaatgtt tggctttttt tagatcttga
    14041 agcagtgaat ccaatttctc ttgtccgtct gtgagaagag tgacagaatt cattcttgtc
    14101 agcggcatac gatttaatga agagaagaag tcaacaaatt gctgtttgtc tttatcgccc
    14161 atgtcaggat cgtaatgttc aatggtatct cctctaaaag actgaaagtt ttctaattct
    14221 ttcaagtcac tttgtcggag atagaatttt ttcttatccg ttaatccacg tccgaaaaat
    14281 aaatataata caaagcccac cccaggaagg gcaaacaata ctaagagcca tgcccaaatg
    14341 gctgctacat ctcggggttt gatcaaaata gccaccaaag caataagtgc atttaataga
    14401 taaagggcgg ttataatact agataccaca aaaatgttcc tccttacata caataacatt
    14461 agtatagcat gatagaagaa agaagcctac caaggtgaat atacttttca ctcctttcat
    14521 gaaaatgtag gtaaatcggg ctaaagtagt tgctttttgt aggttaataa ggtaggatat
    14581 tagtacagtt gaatatctcc ttaggggagt aaccggcaac gtttgttgcg ataatatcaa
    14641 cagtaagtta accaaatggt tttctggtat tgtatgaaat ggtgagacct aagacaaatg
    14701 cgtatttgtc ttaggtctct tttttttcag acaggactag ggccaagatc aaaaaatggg
    14761 ggatgaaatt tggaaaacaa ggaacaagca caacaagcgg tctataaaga aacgatcgac
    14821 tcgttgatgc agcaaacgca gagctcaacc gatggattga gcaccacgca agcgaaggaa
    14881 aaattagaaa gagatggctt gaaccagcta aaagaaaagc cgaagaagcc aacttggaaa
    14941 ttgttcttag aaactttcaa agatgcaatg gttatcgtat tgctgattgt cgcactgatt
    15001 cagatggtca tgggtgacta catcgaattc ttagttattt ttgcagtatt gatgttgaat
    15061 tctataatca gtgttgtcca aacaaaaaaa gcagaaggtt ctttagaagc gttgaaaaac
    15121 ctttcagcgc ccgatgctcg agtgattcgt gatggtaagg aaaaaacgat tccggcaaac
    15181 gaacttgtgg taggagatat cgtgttgtta gacgcaggcg attatgtacc tgctgatgga
    15241 cgtttactag atgcgggatc attaaaagta gatgaaggta tgctgacagg agagtcgact
    15301 tctgcagaaa aagaagtaac ggatatcaca agtacggtac caatcggaga tcgtacaaat
    15361 atggtattca gtggaacgat cgtaacttac ggacgcggta aattcttagt gacttcaact
    15421 gggaataata cggagatcgg acaagttgct ggccttttgg aatcaacaac tgagcaagtc
    15481 actccgttac aacgaggtct ggataaattc agtaaaaaac taagtttggc tattttggca
    15541 ttgtctttat tgattttagg tatccaactg tttcgtattt atcttggaga aggtacagga
    15601 gatatgactg cagatatcgt cagcgcagtg atgtttgccg tagccgtagc cgtagctgct
    15661 attccagaag cattacagtc tatcgtaaca atcgtgttat ctttgggaac gaataaaatg
    15721 gcaaaacgtc atgccattat tcggaagctt ccagcagttg aaacacttgg ttcgacaagt
    15781 atcatctgta cagataagac tggtacattg acacaaaaca aaatgacagt tgttgactac
    15841 tttttaggta atggcgatac tggggatttc acaaatgacc cttcaaaatg gacagctgac
    15901 gaacgtcgct tgatcgaaat cagtgtttta gcgaatgatg catcgatcag tgaagacggt
    15961 actaaattgg gcgaccctac ggaagtagcg tttatcgact ttagtgaaaa attaaaccag
    16021 ccttatcagg aaatccgaaa caactaccca agacaagcag aacttccttt tgactcagat
    16081 cgaaaattaa tgtctactgg acacacaatt gataacaaaa attacttgtt tgttaaaggc
    16141 ggaccagata tcgtcttcca acgcagtaaa aaagtattgc taaatggtga agtcgttccg
    16201 atgacggatg aattgatgaa aaaattccaa gagcaaaatg aagctttttc aacacgcgca
    16261 ttacgtgtac tagcttttgc ttaccgtcca cttgataatt ttgatttatc atttgaagat
    16321 gaagacgatt tgatccttgt tggtttgctt gctatgatcg atcctccacg tgctgaagtg
    16381 actcaggcgg taacagaagc aagaagtgca ggaatcaaaa caatcatgat tactggtgac
    16441 cacaaaacaa cagctgttgc tatcgcaaaa caaatcggga tttttgaaga aggaaacctg
    16501 gctttgaccg ggacggaact agatgaattg acagaagatc aactaaacga agttttagaa
    16561 aaagtcactg tttatgcacg tgtttcacct gagaataaaa ttcgtatcgt tcgtgcttgg
    16621 caaaataaag gtcatatctc agctatgaca ggtgatggtg taaatgacgc accagcattg
    16681 aaacaagcag acatcggaat tgctatggga acgggtacag atgtggcaaa agatgcagca
    16741 gcgatggtat tgacggatga taactttgct tctattgtca gcgcagtaga agtaggacgt
    16801 aatgtgtttg ataatatcaa gaaagctatt tcttatctat ttgcaggaaa tttaggtgcg
    16861 atcattgcga tcatctttgc cttagttgct gactggtcca atccatttac agcattacaa
    16921 ctgttgttca tcaatttagt caatgattca ctgccagcaa ttgcattagg tacagaaaaa
    16981 gctgaacctg ctacgatgaa ccgcccgcca agagatccaa attcaggaat ctttacggac
    17041 aaaacattga tttctgtaac gtatcgtggt gtgctgattg ggattgctgt tatctttgct
    17101 caatggcttg gcatgcagca ttcacctgaa ttcggtgtag ccatgtcatt ttcaacattg
    17161 atttggtgtc ggacattgca aacattccca gcacgttcaa acacacaaac agctatccaa
    17221 gcagggttct tctctaacag aagtgtctta ctagctgtag ttgtatgtag cgcgctttac
    17281 tgcttaacaa tgatcccagg actgaaagaa gtcttctcta tcccatcagc atttggattg
    17341 acagaagtct ttacatgtat gggaatcgca cttgtgacaa ttgttttgat ggaaatcact
    17401 aaattgatca ttgtacgagt acaaggaaat aaataaaacg aatcaacgag gttgtgagcc
    17461 tgccgtttaa ttctgagtca caaggtgcaa tttcaacaaa cagcttctca tgtttgttga
    17521 atattgtgac ttgtgaccga agagttggca ggagaacacc gtttaaggaa gaagttgtaa
    17581 aatcagcatt ttgagctaat actgagggtc atctgattgg acactgttta ttcggaaaga
    17641 gggactttga cacgactttg gtcacagtcc ctttttttat ttatgataga cggaaagcca
    17701 atcattttat tattcatcaa aagagataga atagataaaa gaggagaatg atttattccg
    17761 aaaagtgaaa acatataaca aaaaattaga ggaaatcaaa tgaatgaaaa agaatgggat
    17821 gaatttgctg aagaatatta tgaaatccag caagaatcgc aagtaactat tgctgaagat
    17881 gtaaaaaatt atctgaaaac ggagaaagtc ctgcctgctg aaacagcagc agacgttgct
    17941 ggaggatctg gcagatttct ttccttagca aaagaaatta atcgctatga tttgatcgat
    18001 ttttcttcag gaatgctaga aaatgcaaaa aaagaagcag aaaaaaatga gttgccaaat
    18061 gtttccttta tcaaacagtc gttagaagaa tttatccaat caaatgagac atatgaaatg
    18121 gtttttacag cagcaaatcc agcattggta catcttattc aattagaaaa attgatgaaa
    18181 aagtcaagca aatggtgcgt gataatcaga gtagtggaat caatcgatga tgttttttat
    18241 cctatcgaaa agcaactagg aatgatagaa gaagatccta atacatcgcc agttgtaatg
    18301 gatcaatttg aaacatactt aattgatgaa ggattcaaag tgaagaaaaa agattttact
    18361 tattttacac aggaatcaat tactgaagaa ttgatgaagc tatactatga cgcgtacgca
    18421 aaagatcctg ttgtgaccag gtacattcgc aaactattca gtgaaaaacg agaaatcctt
    18481 agtacgacta agctgaccta tagactgctc ctttggtccg cagataaaaa aagaaccttt
    18541 cacgactcgt gaagggttct ttttatgatt ttattatatt ttgtagtaac gaatatcatt
    18601 ttcgatcttt gtaatcgaaa aaggtacatc tgaagtatat tctgcacatt ctccgtgttc
    18661 aggaagcgtc tcactgaaaa tcgtttcata ttcgtcaaca gtgatccgtg ttcgagaatc
    18721 tagcatctct tgatgagatt gtgcgaagag atattcttga tagttttctt ccagataacc
    18781 tgtaaaaaat tcacttactg caccagaacc gtagctgaat agaccgatgc gatctcctgg
    18841 ctgtagtgat ttcgaatttt ccagtagaga agttagcccc aggtataatg aaccagtgta
    18901 aagattaccg attcgtcggc tgtaacggat gctttcttca tagcgagcca taagacgttc
    18961 ctgattttct tcgtctgttt ggtctaatac gctttgcaat gccttttttc ccatcttagt
    19021 atacggaata tggaaagcaa tcgcctgata atcttcgagt cctcgacccg acaattcttt
    19081 atgtcgattc caaacttttt ggaatgattc gatatacgta gaattagata aaggaccatc
    19141 aacaacagga aattcgctat aatctggacg ccagaaatca tagatatctt ctgtcagaaa
    19201 tacgctgtcg tcttcaatcg ataaaatacg cgggttttga gtgatcatca tcgcaacagc
    19261 accgacacct tgcgtcactt caccaccgct tgccaagctg taacgagcaa tatcacttgc
    19321 tatgactagt acttttcgtt ctggatgatt tttgacatat tctttcgcca tgtgcaaagc
    19381 tgcggtgcca ccgtagcaag cctcttttac ttcaaaagaa cgagcaaaag attggatttt
    19441 cagtaaatgg tggataatta ccgcactcgc ttttgaatga tcaatcccgg attctgttcc
    19501 gacgatgacc atgtcgatta gctcacggtc tttttctgtt acgattttgc tggcagcatt
    19561 tgctcctagt gtaatgatgt cttcatttgc acgattgact gccatttggt cttgaccaat
    19621 ccctatatgg tattttgcag gatcatcccc acggctttct gccaactctg tcatatctaa
    19681 atataaatta ggaataaaaa aggaaagacg atcaatccct attttcattt caacacctct
    19741 ttacttatga taaaaaactt actttactaa ggtatcataa aaagattaaa agaaatataa
    19801 aaaagagaat atttaaggat tgttaaaatt taatcttaga aaaaaataac tggaacaaga
    19861 gctatttgtt tttacagcaa agaatggtat atttttgtag gaggtggctt acttgaaaga
    19921 agtcgttatg atagatgctg caagaacgcc gataggaaag tatcgcggaa gtttaagtcc
    19981 atttactgca gttgaattag gcacacttgt gactaaagga ttattagata aaacaaaact
    20041 gaaaaaagat aaaatcgatc aagtaatatt tggaaatgtc ctgcaagctg gtaatggtca
    20101 aaatgttgcc agacagattg ctttgaacag cggtctccct gtagatgtcc cagcaatgac
    20161 gatcaatgaa gtttgcggat ctggtatgaa agcagtgatc ttagcacgcc agctgatcca
    20221 attaggtgaa gcagaacttg tgatagccgg cggaacagag agtatgtctc aagcacctat
    20281 gctgaaacag tatcagtcag aaacaaatga atatggtgaa ccaatttcca gtatggtcaa
    20341 cgacggattg actgacgcat tttcaaatgc acatatggga ttaaccgcag agaatgttgc
    20401 aacacaattt tctgtgagca gagaagagca ggatcgctat gccttgtcgt cccagttgaa
    20461 agcagcacat gctgtcgaag ccggtgtatt ttctgaggag atcatcccag tcaagatttc
    20521 tgatgaagac gtgttatctg aggatgaagc agttcgtgga aatagtacat tggaaaaact
    20581 gggcacgtta cgtacagtat tctcagaaga aggaactgta acagcaggaa atgcttcccc
    20641 gttgaatgac ggtgcctctg tggtgatcct tgcatccaaa gaatacgcag aaaataataa
    20701 tctgccttat ttagcaacca tcaaagaagt agcggaggtc ggtattgacc caagtatcat
    20761 gggaatcgct ccaatcaaag ccattcaaaa attgacagat agatcaggaa tgaatttatc
    20821 aacaatcgat ctttttgaga tcaatgaagc atttgcagct tcttctatcg tagttagcca
    20881 agaactgcag ttagatgaag aaaaggtcaa tatatatgga ggagcaatcg cattaggcca
    20941 tccaattggt gcaagcggtg cacgtatctt gactacatta gcttacggat tgcttcgtga
    21001 acagaagaga tacggtattg cttcattatg tattggtgga ggtttaggct tggcagtctt
    21061 gttagaagcg aatatggagc aaacacataa ggatgtgcaa aaaaaaaagt tttatcagct
    21121 tacgccatct gaacggcgca gtcaattaat agaaaaaaat gtattgacac aagaaactgc
    21181 gttgattttt caggaacaaa cactttctga agagctctcc gatcacatga tcgaaaacca
    21241 agtgagtgaa gtggaaatcc caatggggat cgcgcagaat tttcaaatca atggcaagaa
    21301 aaaatggatt ccgatggcaa cagaggaacc atctgtcatt gcagctgcaa gtaatggtgc
    21361 aaaaatctgt ggaaatatct gcgcagaaac acctcagcgg ctgatgcgag ggcaaatcgt
    21421 tctatcagga aaatcggagt atcaagcagt gatcaatgca gttaatcatc gaaaagaaga
    21481 gctgattctt tgtgcaaatg aaagttatcc ttcaatcgtg aaacgcgggg gcggtgttca
    21541 agatatctct actcgggaat tcatggggag tttccatgca tacttatcta ttgatttttt
    21601 agtggatgta aaagatgcaa tgggcgctaa catgatcaac tcgattcttg agagtgtggc
    21661 aaacaagtta cgggagtggt tccctgaaga agagattcta ttcagtattt taagtaattt
    21721 tgctacagaa tcattggctt ctgcctgttg tgaaatccca ttcgaacgct tagggagaaa
    21781 caaagaaatc ggtgaacaaa ttgccaaaaa aatccaacag gcaggggaat atgcgaagct
    21841 tgacccttac cgtgcagcaa cgcacaacaa agggatcatg aatggtatag aagctgtagt
    21901 ggcagctaca ggaaatgata cacgtgcggt tagcgcttcg atccacgcct acgcggcaag
    21961 aaatggatta taccaaggat taacagactg gcagatcaaa ggggataaac tagttggaaa
    22021 actaacggtg cctttggctg ttgccacagt aggcggagct tccaatatcc tgccaaaagc
    22081 aaaagcatct ttagctatgt tagatattga ttcagccaag gaactagcac aagtaattgc
    22141 tgcagtaggg ttagctcaaa acctggctgc tttgcgtgca ttagttacag aaggaatcca
    22201 aaaaggccac atgggacttc aagctcgttc attagcgatc tcaattgggg ctattggtga
    22261 ggaaatcgag caagttgcga aaaaattacg tgaagcagaa aagatgaacc agcagacagc
    22321 tatacaaata ttggaaaaaa tccgggaaaa ataaaaaagc aatatcttta gaagaataaa
    22381 gcaagattta cagttatttt atttactgca gatcttg
//
LOCUS       DAZKKZ010000050        22034 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.051, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000050 DAZKKZ010000000
VERSION     DAZKKZ010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22034)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22034)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22034
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.051"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..287
                     /locus_tag="ACG8LA_002004"
     CDS             <1..287
                     /locus_tag="ACG8LA_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204298.1"
                     /translation="KSFLKVISKKRNLIKTTQLLKKYPGLLHTSIQFPQLITMIHRFI
                     RMQQLPSKKLFLPLTDTFRVVNREDKKKVIVIDFTRNRNVLHQVAMEKAN"
     gene            346..786
                     /locus_tag="ACG8LA_002005"
     CDS             346..786
                     /locus_tag="ACG8LA_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204299.1"
                     /translation="MMQTWLERLIRFQQNYHKLMQGRYAKFDQLNRGLLIAALVFSLL
                     SRWLPYRIGQLLFIVFFGWMIFRFLSKKIYPRLNENQRYLKYLDRVKEKYHQIKNKKQ
                     VKMDRKSYTFFECPNCHQKQRAPKGKGRIRVTCKTCGIKFETNV"
     gene            798..1466
                     /locus_tag="ACG8LA_002006"
     CDS             798..1466
                     /locus_tag="ACG8LA_002006"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004619 - phosphoglycerate mutase activity
                     [Evidence IEA];
                     GO_function: GO:0016868 - intramolecular
                     phosphotransferase activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HFQ0204300.1"
                     /translation="MKLVLLRHGESEANFENYWTGWLDVALTEKGKEQAAVAGQKMLE
                     AGLQFDAVYTSVLKRAILTGQVALEEMGQLWLPIIKTWRLNERHYGDLVGKNKDKMKE
                     IYGKDQVKTWRRGYTEVPPLTAENRFDRRYDHLDPHLIPYGESLEMTVNRIIPLWQDH
                     LAPKLKDRQDLLVVGHGNSIRALTKYLEDVPEDQMDTIDIPNAQPIQYTLADDLTILD
                     KKIL"
     gene            1530..2153
                     /locus_tag="ACG8LA_002007"
     CDS             1530..2153
                     /locus_tag="ACG8LA_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HFQ0204301.1"
                     /translation="MKNYIWDFDGTLFDTYPAMVDGAWQALKDFGISMDKKEIYFKMK
                     KYSTSYLINESNLNAREFNELFHRYEKESTEVSRPFPETKQVLEMLKDNGGRHFILTH
                     RLTESTWGLLKEHRLAHLIEEVVGIDQDFPRKPDPASLNYLIDTFHLERTDTMMIGDR
                     RLDIEAGKNAGVATCLYDIDHFLGEIPADYVVGNLNEILTLQSIIKK"
     gene            2209..2595
                     /locus_tag="ACG8LA_002008"
     CDS             2209..2595
                     /locus_tag="ACG8LA_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HFQ0204302.1"
                     /translation="MEIRRQKEVVEAFHYDMRLPNQEVETDLKVGFSPLKETIENYPK
                     EHSIVGARLEFRLVFDTYVLSGSVSQINHILNRKIEGQNDVTQEEVDELVAPLFDIVR
                     RMSYEVTEIALDQPGVKLNFQSEKQE"
     gene            2808..4199
                     /locus_tag="ACG8LA_002009"
     CDS             2808..4199
                     /locus_tag="ACG8LA_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-cystine transporter"
                     /protein_id="HFQ0204303.1"
                     /translation="MTTLITVLVVLVFAALLYVFYRMQKRHTKFSTRVFTALGVGIVF
                     GGLLQLIFGVDDKVVTQSMEWIGIVGQGYVSFLQMLVMPLVFISIIGAFTKMKVSEKL
                     GKISATVLTSLLGTTAIAALIGIGSTMLFGLQGAKFTQGAAETARISELATRQETVEN
                     LSIPQQILSFIPKNVFADLAGSRATSTIGVVIFAAFVGIAYLGVKRKAPKEAAFFSDL
                     VDSLYKIIMRIVTLVLRLTPYGVFALMTNVLATSDFAAIVNLGKFVVASYVALLAVLI
                     VHSLILIGAKVNPINYFKKAFPVLSFAFTSRSSAGALPLNIETQTKALGVDDATANFS
                     ASFGLSIGQNGCAGVYPAMLATIVAPAAGVNVFSLEFILMLVAIVTISSFGVAGVGGG
                     ATFASLIVLGAMNLPVAIVGLVISVEPLIDMARTAVNVSGSMVAGIVTSARIKDLDRD
                     VINDDSKVIDVNA"
     gene            4810..5178
                     /locus_tag="ACG8LA_002010"
     CDS             4810..5178
                     /locus_tag="ACG8LA_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="HFQ0204304.1"
                     /translation="MFTNEIKIMLYVDDVEKNATFWRAVGFAEKDRQEMDGTLIIEVG
                     VEDSQTSFLLYDRAFVESHSPGTATSAPSLMFYSKDIFGLYKKMQTQSVTLGDMVQLG
                     EEYVFNFADPDGNYFAVTGK"
     gene            5358..6299
                     /locus_tag="ACG8LA_002011"
     CDS             5358..6299
                     /locus_tag="ACG8LA_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HFQ0204305.1"
                     /translation="MDYQVLLYYNYTKIEEPEEFAKNHLAFCKSLDLKGRILVAEEGI
                     NGTVSGTVENTTAYMKAMKADPRFADTMFKIDPSEGHAFKKMFVRYRPELVSLKLEED
                     IDPNQVTGAYLSPQEFKEAILDEQTVVIDARNDYEYDLGHFRGAVRPDIRSFRELPDW
                     IREHKEEFMEKRVVTYCTGGIRCEKFSGWLVREGFKDVGQLHGGIATYGKDPEVQGEL
                     WDGKMYVFDERIAVDINQVDKQIVGRDWFDGTPCERYINCSNPECNRQILASIENEEK
                     HLGACSIECAKHPRNRYVQDHGISPEEAELRFTALIK"
     gene            6368..7099
                     /locus_tag="ACG8LA_002012"
     CDS             6368..7099
                     /locus_tag="ACG8LA_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HFQ0204306.1"
                     /translation="MKSLIYAIGDVHGKHELFEKLIHYYDPKIHQLVLLGDLNDRGPR
                     TKECFLLGKQLVEETGAIYLRGNHEEYFLQFLQSPEDWYAPYMRNGGKETFESLIHPG
                     ASEEYSPTEISMMIQSRYSELIKFLVQRPLYYEWENYLFVHAGVDLTKKDWRKTSLRD
                     FIWIREPFHEGKNNTGKTIVFGHTITPMLHGDMQTTDLWIQDHKIGMDGGAVFGGSLH
                     GVVFDKEGILQDIEYQNNEGPWHGI"
     gene            7243..9423
                     /locus_tag="ACG8LA_002013"
     CDS             7243..9423
                     /locus_tag="ACG8LA_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003729 - mRNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Tex family protein"
                     /protein_id="HFQ0204307.1"
                     /translation="MTENLNQTIIQLVQKELSDYRPKQLTTVLNLLNEGNTVPFIARY
                     RKEMTGSLDEVQIREIEERYAYLENLEKRKTEVIRLIDEQGKLTPELEAEITQAVKMQ
                     QVEDLYRPYKQKRRTKATIAKEKGLEPLAKWLMQLTDGEVQSEAEKYIDKEKEVSSAE
                     EALHGAHEIIAEQVSDNAKFRTWIRSYTYNKGMYVSNVKDEQADEKGVYEMYYDFAEP
                     VHKMVSHRILATNRGEKEDILKVFFQVDEAAILAYLDRQIVKNPASPSSSFVREAYQD
                     SYKRFIQPAIERELRNELTEKADEQAIAIFGENLRNLLLQPPLKGKVVLGFDPAYRTG
                     CKLAVVDATGKVLAIEVIYPHKPAAQAKREAAGPAFIQLINKYQVDMVAIGNGTASRE
                     SELFVAEQLKSADHKTYYAIVNEAGASVYSASEIARKEFPHLQVEERSAVSIARRLQD
                     PLAELVKIDPKAVGVGQYQHDVSQKRLAEQLDFVVETAVNQVGVDVNTASPQLLQHIS
                     GLNKTTAQNIVIYREENGEFTARTQLKKVPRLGPKAYEQAIGFLRVPGGKNILDNTGI
                     HPESYSIAKEILTSVQLSEKELGTEEAVEKLTRLSVEKLAESLSVGEETLADILAGLT
                     QPGRDMRDEMPAPLLRTDVLSMEDLKPGMELTGTVRNVIDFGAFVDIGVKQDGLVHIS
                     KLSKKFVKHPTDVVSVGDIVTVWIEQVDTKKGRISLTMLSPYEE"
     gene            9443..9925
                     /locus_tag="ACG8LA_002014"
     CDS             9443..9925
                     /locus_tag="ACG8LA_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HFQ0204308.1"
                     /translation="MTQEELQQLVEEISLKSFQLPFKHQAMFNPRLRTTGGRYHLNDH
                     HLDFNAKLFEESDEETIAGIIKHELCHYHLHLAGRGYQHKDMDFKYLLKKTGGLRYAP
                     ALTKKQIKMEYYRCQDCSATICRKRRIDVRKYRCGRCHGEIKWIETKREDFNEAQKIR
                     "
     gene            9941..10702
                     /locus_tag="ACG8LA_002015"
     CDS             9941..10702
                     /locus_tag="ACG8LA_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HFQ0204309.1"
                     /translation="MEKSEQRNLKDWNQLLNFLAAPEEGNFEELTAPTLILAGNCLPI
                     LADKAAQMYLNGQVDQLFLVGGVGHATRILYENFEKQGFHFEDGMSESEICRQYLKEV
                     YDLPDKAFLIESKSTNSGENATFSLEILHSLGAVPEKILLMNDPTLQRRTRATFEKVW
                     QNEQTIFANAVPFVPEILHFSEEIIFTAKELNHQWPKEYFHALVLGEMERLHDDENGY
                     GPKGKDFIPHIDISEEVWSSYTRIKESIKTDFSRT"
     gene            10833..12167
                     /gene="murC"
                     /locus_tag="ACG8LA_002016"
     CDS             10833..12167
                     /gene="murC"
                     /locus_tag="ACG8LA_002016"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008763 - UDP-N-acetylmuramate-L-alanine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HFQ0204310.1"
                     /translation="MENQNKLYHFVGIKGSGMSSLALVLHEQGLNVQGSDIEKYFFTQ
                     RDLEKANITILPFNADNVKPGMTIIAGNAFPDSHEEIQRAKELGLEVIRYHDFIGHFI
                     QNYTSIAVTGSHGKTSTTGLLSHVLSGVRPTSYLIGDGTGHGDPQAEFFSFEACEYRR
                     HFLAYSPDYAIMTNIDFDHPDYYTSIDDVFTAFQTMAGQVKKAIFAYGDDAYLRKLKA
                     NVPIYYYGVTENDDIQARNIERTTSGSAFDVYHGDEFVGHFTVPAFGKHNILNALGVI
                     AVAYFEKLDLKEVAEEMLTFPGVKRRFSEKIVADMTVVDDYAHHPAEIKATIDGARQK
                     YPDKEIIAVFQPHTFTRTIALMDEFAEALDLADKVYLCDIFGSAREEQGNVKIEDLGA
                     KIKKGGEVIKENNVSPLLDYHDAVVIFMGAGDVQKFEQAYEKLLSSTTKNVL"
     gene            12474..12959
                     /locus_tag="ACG8LA_002017"
     CDS             12474..12959
                     /locus_tag="ACG8LA_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MaoC/PaaZ C-terminal domain-containing protein"
                     /protein_id="HFQ0204311.1"
                     /translation="MNIGKPRKLGKTINEIEEGDSLSLTESIEDNQLLLYLGLTNDAN
                     PLYIQHDFAQKTEYQQPIVPSVMLMGIITSAISKHLPGPGSHVVNFSVNFIEPVFHYE
                     TLTFQFEVIKVDKMKDVVTISVEAENTNEDRVLDAVVMVQPPQVPELEIAIESEGELN
                     E"
     gene            12952..13635
                     /locus_tag="ACG8LA_002018"
     CDS             12952..13635
                     /locus_tag="ACG8LA_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HFQ0204312.1"
                     /translation="MNNPSTSMSGINRFYAKVYGFLGMGLALSAVTSYLALWVFPLQL
                     ATFINNFPLGFVGLWIVELILVMVLGVKAQKNPSLAIGGFIAYSLLNGITLAVTLAYY
                     DIGTVTQAFLTATLMFMGMSVVGVTTKRDLSGVGRAGQAALIGVIIALVLNIFILRSS
                     VVELFISLLLVVIFAGITAYDNQSIRNIYVQTNGTAHSGIAVFMALKLYLDFINLFLA
                     FLRIFGRNN"
     gene            13761..16406
                     /gene="polA"
                     /locus_tag="ACG8LA_002019"
     CDS             13761..16406
                     /gene="polA"
                     /locus_tag="ACG8LA_002019"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006261 - DNA-templated DNA replication
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HFQ0204313.1"
                     /translation="MTKNKLLLVDGNSVAFRAFFALHNSLERFKNRNGLHTNAIYAFN
                     TMFENVMQKEQPTHVLVAFDAGKTTFRTEMYAEYKGGRSKTPGEFKEQMPYIRDLLTG
                     LGVQYYELPNYEADDIIGTLAEKVDKDQFDVVVLSGDRDLTQLASKEVKVDITVKGVS
                     DIESYTPEHVAEKYDGLTPKQIIDMKGLAGDASDNIPGVTKIGEKTAIKLLKQYGSVE
                     GIYEHIDEMKQSKMKENLINDKEQAFLSKKLATINTSAPVDVSIDSLKYEGKNLDKLV
                     PFYKEMDFNQFLSKLNIVEEEVKMDDILFEVVHEFKEEMFTTDMALYVEMMGDNYHTE
                     EIVGVAWGTEKKIYVTNDLSVFENRAFHSWITDPTRLKKVYDAKRTYVALNRYTGKTK
                     GIDFDVLLGAYLLDTNEKSTDIEGIAAHYGYNDIQSDEAVYGKGAKKGLPEEEELFFA
                     HLARKVAAINALTPKLSQELAEKNQEDLFRKMELPLSIILAEMEISGIKVDATRLQEM
                     KGEFSARLREIEQKIYEEAGEEFNLNSPKQLGVILFEKMGLPVIKKTKTGYSTAVDVL
                     EQLREQAPIVEDILTYRQIAKIQSTYVEGLLKVIQSDGKVHTRYVQTLTQTGRLSSVD
                     PNLQNIPIRLDEGRKIRQAFVPREKDWLIYSSDYSQIELRVLAHISNDEHLKAAFLEG
                     QDIHASTAMRVFGIEKAEDVTPNMRRQAKAVNFGIVYGISDYGLSQNLGISRKAAQQY
                     IDTYFEKYPGVKEYMERIVREAKDQGYVETLYHRRRYLPDINSRNYNIRSFAERTAIN
                     TPIQGSAADILKIAMIELDKRLKETGLQATMLLQVHDELVFEVPEKELESLDKLVKEV
                     MEQAVSLHVPLITDSSWGKTWYEAK"
     gene            16451..17287
                     /gene="mutM"
                     /locus_tag="ACG8LA_002020"
     CDS             16451..17287
                     /gene="mutM"
                     /locus_tag="ACG8LA_002020"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008534 - oxidized purine nucleobase
                     lesion DNA N-glycosylase activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HFQ0204314.1"
                     /translation="MPELPEVETVRKGLERLVVGKTIQKVQVLWPKIIEQPETPIFEA
                     SLVGETIQSIGRRGKFLIFHLDHCELISHLRMEGKYQFTKENTPIDKHTHVLFFFEDG
                     SQLRYNDVRKFGRMTIVEKGASATYRGIMKLGPEPLPDSFLLADFANGLKKSHKAIKP
                     LLLDQRLVTGLGNIYVDEALWEAKIHPEQPANTLRPKEVEQLRLSIIDVLDRAIEAGG
                     TTIRSYLNALGESGGFQVALHVYQQTGKPCIRCGTPIVKTKVAQRGTHYCPNCQRLKI
                     AK"
     gene            17251..17880
                     /gene="coaE"
                     /locus_tag="ACG8LA_002021"
     CDS             17251..17880
                     /gene="coaE"
                     /locus_tag="ACG8LA_002021"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340744.1"
                     /note="Dephospho-CoA kinase (CoaE) performs the final step
                     in coenzyme A biosynthesis; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004140 - dephospho-CoA kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HFQ0204315.1"
                     /translation="MSELSKAKNRKVGFVLGLTGGIATGKSTAAKVFQSHGFPLIDGD
                     VIARETVEPGTLALRKIVSVFGQEVLQPDGQLDRGKLGMIVFPSKEKRQKLDQLLDPF
                     IRKAIKDQIASLSSNHPLVIVDIPLLYEGHYDHYMDAVAVVYTTPETQLQRLMKRNQL
                     TLEQAQQRISSQLPIEEKKQRADILFDNNGTKEKLVGQIENWLFANRFL"
     gene            17932..18264
                     /locus_tag="ACG8LA_002022"
     CDS             17932..18264
                     /locus_tag="ACG8LA_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HFQ0204316.1"
                     /translation="MGSLKNQKDKVVGNAKEKIGEMLNKENLIDEGRTQSETAEEKEK
                     QYQARIDEIEDQQAEEEAKRQDLTQERKNPTPDRSKTPLPESDHIPDEQKIEEQRMKH
                     YTGIEEKL"
     gene            18576..19067
                     /gene="nrdR"
                     /locus_tag="ACG8LA_002023"
     CDS             18576..19067
                     /gene="nrdR"
                     /locus_tag="ACG8LA_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0140110 - transcription regulator activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator NrdR"
                     /protein_id="HFQ0204317.1"
                     /translation="MRCPRCQHNNSRVIDSRQADDGRAIRRRRECENCSFRFTTFERI
                     EAAPLLVIKKNGEREEFNRDKILRGLIRSAEKRPVAMEQMEQIVNHVENRVRSLGENE
                     VSTNLIGEYVMEDLVDLDEIAYIRFASVYRQFKDMSVFLKELQDIVDKAKENNKENNK
                     ENN"
     gene            19090..20463
                     /locus_tag="ACG8LA_002024"
     CDS             19090..20463
                     /locus_tag="ACG8LA_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HFQ0204318.1"
                     /translation="MENAWKELQPKNIYQGRKAAPLREDSKNALLYLYQPLIGGEALS
                     IYFTLLSEISQESGKGPEGMHADLLSSLGCGIPQFYDARKKLEGIGLLDVYFKEDSDL
                     GPRFIYELLEPLIPKAFFKDSVLAFLLLEKVGERRFQKLTQFFEPKRHTAEGYQKITK
                     KFLDVYRFNEAVYAANQENIESLNKSFEESESVALLEADSTFDWQFLNDWLAKKHIAS
                     LDDPIIKQVDMYHQLYGFDELTLGELISQSYDFSEQKVSEKELQKAILAMQRRPVKQT
                     KETVAVSENSNEPSSNEHLTNAALQLIKEAQSIPPMKYLEAIKSEKGGYVSKQENWLL
                     QDLVSQSGLSSSVINVLLNYVLVIKNNASLNASYVNTVANEWAQKKIATAEEAIQHIR
                     QISNQAKQSKQKKQTNYQTGKRNVRREKLPDWVNQPKDEKQISSEKKAEIDRRFKEYL
                     AKKEGDI"
     gene            20463..21389
                     /gene="dnaI"
                     /locus_tag="ACG8LA_002025"
     CDS             20463..21389
                     /gene="dnaI"
                     /locus_tag="ACG8LA_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HFQ0204319.1"
                     /translation="MEDVGKELKRIISKRNYQEKYAEMIAEVLNDADVQAFLSAHQEE
                     LTQADIEKSYAKLYEFVQEKRKYQKNDPTMIAPGYEPKLTLNFHYVDVTYVPTEALLA
                     RQRQEEIRSRVKAMDMPKDIQSASFENFERTDGRGYASLEALDFVEKYTADPKGYHKG
                     LYLVGSFGIGKTYLLGATARELAIAGFTTTLVHFPTFAVEMKQAIGKDQVAEKLDAVK
                     RSPILMIDDIGADAMSSWIRDEVFGVILQYRMQEQLPTFFSSNFTMDELEQHLSVTQR
                     GDEEPLKAKRIMERIRYLTKEIEMTGRNRRNG"
     gene            21518..21958
                     /locus_tag="ACG8LA_002026"
     CDS             21518..21958
                     /locus_tag="ACG8LA_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HFQ0204320.1"
                     /translation="MRAIFSSISVVGLFFLLAGCGSADSNTGSVDSIDAGQTVKTSST
                     KTERQSIFVGTIESITQVEAEEETLQLKLVDVMAKEDPANMGTSFSNDGVILNATAEK
                     ISVDINELKIGDKVQFTLVEMPIMTMSIPPQVPGDSIIDVSLNK"
BASE COUNT         7473 a         3813 c         4810 g         5938 t
ORIGIN      
        1 taaaaagctt tttaaaagtg atcagtaaaa aacggaatct gatcaaaacg acacagctgt
       61 tgaaaaaata tccaggtctg cttcacacgt ctattcaatt tcctcaattg attacgatga
      121 tccatcgttt tatacgtatg caacagctac catctaagaa gctgtttctt ccattgacgg
      181 acacatttcg agtagtcaac agagaagata aaaagaaagt gattgtgatt gactttacca
      241 gaaatcggaa tgtccttcac caagttgcaa tggaaaaggc caattaaggc tttttctttt
      301 tggatttttt tgtcataata aatattagat gatggaggag ataatatgat gcaaacatgg
      361 ttagaaaggc taatacgatt tcagcagaac tatcacaaac ttatgcaggg aagatatgcg
      421 aaatttgatc agttgaatcg cggtctattg atcgctgcgc ttgtctttag tttgctaagt
      481 cgttggttgc cctatagaat cggacaattg ttgttcatcg tctttttcgg atggatgata
      541 tttcgtttcc tatcaaaaaa aatctacccc agactaaatg agaatcaacg ttatttgaaa
      601 tatcttgata gagtcaaaga aaaatatcat cagataaaaa acaaaaagca agtcaaaatg
      661 gatcgaaaaa gttatacttt ttttgagtgc ccgaattgtc atcaaaagca gcgtgcacct
      721 aaaggaaaag gacgaatacg tgtgacatgc aaaacatgtg gtataaaatt cgaaacgaat
      781 gtttaaggga gaaaagaatg aaattagtat tattacgtca tggcgaaagc gaagcaaatt
      841 ttgaaaatta ctggacagga tggctagatg tcgccttaac agaaaaagga aaagaacaag
      901 cagcagttgc cggtcaaaaa atgcttgaag ccggacttca attcgatgcc gtttatacct
      961 ctgttttgaa acgtgcgatt cttaccggac aagtcgcact agaagaaatg ggtcagttat
     1021 ggcttcctat aataaaaaca tggcgtctaa atgaacggca ttatggggat cttgtgggta
     1081 aaaacaaaga taagatgaaa gaaatatacg gaaaagatca agtaaaaaca tggcgcagag
     1141 gatatacgga agttccgccg ttaaccgcag aaaatagatt tgaccgcaga tatgatcact
     1201 tggatccgca tttgatccca tacggagaaa gtctggaaat gacagtgaat cggatcattc
     1261 ccttatggca agatcatcta gcaccaaaac taaaagatcg gcaagattta ctagttgtgg
     1321 gtcatggtaa tagcatccga gcactgacaa aatatttaga agatgttcct gaagatcaaa
     1381 tggatacgat cgatatccca aatgcacaac caatccagta tacattagca gatgatttga
     1441 caattctgga caaaaaaata ctttaaagaa cacctttatc taaaagtgag agatagaaaa
     1501 aagaagcaaa ggaatggaac aaaaggaaca tgaaaaatta tatatgggac tttgatggta
     1561 cattgtttga tacgtatccc gcaatggtag atggtgcatg gcaagcacta aaagattttg
     1621 gtatcagtat ggacaaaaaa gaaatctact tcaaaatgaa aaagtattct actagttatt
     1681 tgatcaatga atcaaacttg aatgccagag agtttaatga attatttcac cgatatgaaa
     1741 aagaaagtac ggaagtttcc cgtccatttc cagaaacgaa acaagtactg gaaatgctaa
     1801 aagacaacgg cggtcgtcat ttcatcctga cccaccgttt gacagaatca acatggggcc
     1861 tgttaaaaga acatcgattg gcacatctga ttgaggaagt agtagggatc gatcaggact
     1921 ttcctcgtaa acctgatcca gcatctttaa attatttgat cgatactttt catttagaaa
     1981 gaacagacac gatgatgatc ggcgatcgtc gtttagatat cgaagcaggg aaaaatgcag
     2041 gagtcgctac ttgtctttac gacatcgatc attttctggg tgagatcccg gcagattatg
     2101 tggtaggaaa tctgaatgaa atccttacct tgcagagcat cattaaaaag tagtatcccc
     2161 tttcaaagga gatatgttat aattttcata aaggagtgat aaaattatat ggaaatcaga
     2221 agacaaaaag aagttgtaga agcatttcat tatgatatga gattgccgaa ccaagaagta
     2281 gaaacagatt tgaaagtagg cttctcgcct ttaaaagaaa cgatcgaaaa ctatccgaaa
     2341 gaacatagca tcgtaggagc acgcttagag ttccgtttag tgtttgatac atatgtttta
     2401 tctggaagtg tgagtcagat caatcatatc ctcaatcgga aaattgaagg tcaaaatgat
     2461 gtcacacaag aagaagtgga cgagctagta gcaccgttat tcgatatcgt acgccgaatg
     2521 tcttatgagg tgacagagat cgccttagat cagcctgggg taaaattgaa ttttcaatca
     2581 gaaaaacaag aatagacagt aaaaacatac ctgcgataga ttaaagctat cacaggtatg
     2641 tttttttatt actaattgta agcaaaaaga atgtcatttc gataaaaatc gtctaaaata
     2701 taaaagtcac tgaaaaaaat tttttcagga ggatggttga agaatcattc tcgggaacct
     2761 ttacttcctt cgatggactt gtcattaata atatgaggag gagaaaaatg acaacactca
     2821 tcacagtttt agtggttcta gtttttgcgg cattattata tgtgttctat cgtatgcaaa
     2881 agcgccatac aaaattttca acacgcgtct ttacagcatt aggagttggt atcgtctttg
     2941 gcggtctgct tcaattgatc tttggtgtag acgacaaagt cgttactcaa tcaatggaat
     3001 ggatcgggat tgtaggtcaa ggatatgtat cattcttgca aatgctagtt atgcctttag
     3061 tgtttatttc gatcattggt gcattcacaa aaatgaaagt ttctgaaaag ctagggaaaa
     3121 ttagtgcgac tgtattgact tctttacttg gaacaacagc tattgcagca ttgatcggaa
     3181 ttggttcaac aatgctgttc ggactccaag gagctaaatt cacacaagga gctgcagaaa
     3241 cagcacgaat ctctgaactg gcaacacgtc aggaaacagt tgaaaactta tcgattccac
     3301 agcagatttt atcctttatc cctaaaaacg tttttgctga tttagcaggt agtcgtgcaa
     3361 caagtacgat tggagtcgtt attttcgcgg catttgtcgg aatcgcttat ctaggcgtga
     3421 aaagaaaagc gccaaaagaa gcagcattct tttcagattt agtcgacagt ctgtataaaa
     3481 tcattatgcg gatcgtgacg cttgttttgc gtttgacacc ttatggagta tttgctttga
     3541 tgacaaacgt tttggcaaca agtgattttg cagctatcgt caatttaggt aaatttgtcg
     3601 ttgcttctta cgtagcattg cttgctgttt tgattgtcca ctcactgatt ttgattggtg
     3661 caaaagtcaa tccaatcaac tatttcaaaa aagcctttcc ggtattgagc tttgcgttta
     3721 cttcacgttc aagtgctgga gctttgccat tgaatatcga gactcagaca aaagctttag
     3781 gagtagatga tgcaacagct aatttctcag caagttttgg tttgtctatt ggacaaaacg
     3841 gctgtgctgg cgtttatcca gctatgttgg caacgatcgt cgcaccagca gctggagtga
     3901 atgtctttag tttggaattt attttgatgc ttgtggcaat tgtaacaatc agttcttttg
     3961 gtgtagctgg agtcggtggg ggcgcaacat ttgcttcact gatcgtttta ggggcaatga
     4021 acttgccagt agcaatcgtt gggttagtta tctctgttga accattaatc gatatggcac
     4081 gtacagcagt aaacgtcagc ggtagcatgg tagctggtat cgtgacaagt gcacgcatca
     4141 aagatttaga tcgcgatgtc atcaatgatg attctaaagt gatcgatgtg aatgcatagt
     4201 caaaaagagg ttgtgataga agtggtcagc tttaagaaat aagaagaagt ttcctaaaaa
     4261 tagtttctca aatttttgtg aaatttcggc ttatttccga gaagctactt ctgaaacacc
     4321 gtgaataaga ggttgtgaaa aagctgccct gcatcaagta ataagaacag ccaaacaaaa
     4381 atagttcctc atattttacg tttggttgag cttattaccg cagatgcaag cttttgaaca
     4441 ccgtttaaga aagaggtcgt gagcctgccg tttcactctg agtcacaaag agcaatttca
     4501 aaaaatagct tctcatgttt gttgaatatt gtgtcttgtg accgaggagt tgtcaggaga
     4561 acaccgttta ccagaggttg tgacttgttt ttagtcacga cctctttttt tatttattcc
     4621 atataaatac acattattta ttccgaaaag tgaaagcgca aataacaaaa acaaccaact
     4681 tatttattat taaagaaaag cgtatttaag taggacgatt ctgttgagag ctttcgtaga
     4741 ttttcccatt ttcctatggt aaactgacaa agttgagaat gttagaacag atcgtttagg
     4801 aggaaacaga tgtttacgaa tgaaataaaa atcatgcttt atgtggacga tgtagaaaaa
     4861 aatgcaacgt tttggagagc agttggcttt gcggaaaaag atcgtcaaga aatggatggg
     4921 acgcttataa ttgaagtagg agttgaggac agtcaaacct catttctgtt atatgatcga
     4981 gcatttgttg agtcccattc acctggcaca gctactagtg ccccatcttt gatgttttac
     5041 agtaaagata tctttggact atataaaaaa atgcagacgc aatcagtcac attaggtgat
     5101 atggtacagc ttggagaaga atatgtcttt aactttgctg atcccgatgg caactacttt
     5161 gcggttacag gtaaataata gaaataaaga ctttgttttt ctgtgcgaaa caggaaagcg
     5221 aagtcttttt aattcaaata ataatattat gtaaacaaaa aactttccat gcgtaattat
     5281 acacaagcaa ataaatcgtc aaatgcgaac gccttcttta tactgtttag gaacgaaaag
     5341 aaggaaggaa gaaatacatg gattatcaag tactgcttta ttacaattat acaaaaatcg
     5401 aagaaccaga ggaatttgcc aaaaatcatt tagccttttg caaatctttg gatcttaaag
     5461 gtcgtattct agtagctgaa gaaggaataa atggtactgt gtctggaacc gttgaaaaca
     5521 cgactgccta tatgaaagca atgaaagctg atcctcgatt tgctgatacg atgttcaaga
     5581 tcgatccaag cgaaggacat gcctttaaga agatgtttgt aagataccgt ccagagcttg
     5641 taagtttaaa gctagaagag gacattgatc caaaccaagt gacaggtgcc tatctttcac
     5701 cgcaagaatt taaagaagct attttagatg aacagacagt ggtgattgat gcacggaatg
     5761 attatgaata tgacttggga cattttcgag gggctgtacg cccagatata cgcagttttc
     5821 gagagcttcc agactggatc cgcgagcaca aagaagaatt tatggaaaaa cgggtagtga
     5881 cctactgtac tggtggcatt cgttgcgaga agttttctgg ttggcttgtc cgtgaaggat
     5941 tcaaagatgt cggacagctg catggcggta ttgctactta tggtaaggat cctgaagtcc
     6001 aaggagaatt atgggacggc aagatgtatg tgtttgatga acggatcgct gtcgatatca
     6061 accaagtaga taaacaaatc gtcggtcgcg actggtttga cggaacacca tgtgaacgat
     6121 atatcaattg tagcaatcct gagtgcaatc gtcagattct tgcttccatt gaaaatgaag
     6181 aaaaacattt aggagcatgt agcatagagt gtgcgaaaca tccgcgcaat cgctatgttc
     6241 aagaccatgg aatctctcca gaagaagcag aactgcggtt tacagcttta attaaataga
     6301 aaacaatagt tttgattgtc gaccatttcc aatatgcgct atactagcgt tgaggatggt
     6361 gatccacatg aaatcattga tttatgctat tggggatgtc catggcaaac atgagctttt
     6421 tgaaaaactt attcactatt atgatccaaa gatccatcag cttgttttat taggggatct
     6481 caatgatcga ggtcctcgta caaaagaatg ttttttatta ggaaagcaat tagtcgaaga
     6541 aacaggagcc atttacctcc ggggaaacca tgaagaatat tttttgcaat ttctgcaatc
     6601 accggaggac tggtatgcgc cttatatgag aaatggtgga aaagaaacgt ttgaaagcct
     6661 gattcaccca ggggcatcgg aggaatactc cccaactgaa atctcgatga tgatccaatc
     6721 gagatattca gaactgatta aatttttagt ccagcgcccc ttgtattatg aatgggaaaa
     6781 ttatcttttt gtccatgccg gtgtggattt gacaaagaaa gactggcgta agacaagtct
     6841 aagagacttt atttggataa gggaaccatt tcatgaaggg aaaaacaata caggtaagac
     6901 aattgtattt ggacatacga ttacaccaat gctccatgga gatatgcaga caacagacct
     6961 ctggattcag gatcataaaa tcggaatgga cggtggggct gtattcggag ggtcattgca
     7021 tggggttgtt tttgacaagg aaggtattct tcaagatatt gaatatcaga acaacgaagg
     7081 accttggcat ggaatctgac taatggaaag aatgaaggag ctgtgacttt gttgcggctc
     7141 tttttatttt tatagagaat attgtttctt tcagtagttt aacccaggat aaaaagtatg
     7201 atagaataaa gaagcaattt ttagcagaaa agaggcattt taatgacgga aaatttgaac
     7261 cagacgatca ttcagcttgt acaaaaagaa ctttcagact atcgtcctaa gcagttgact
     7321 actgtactta atttgttaaa tgaaggaaac actgttcctt ttatcgcgcg ttaccgaaaa
     7381 gaaatgactg gaagtcttga tgaagtccag attcgtgaaa tcgaagagcg gtatgcctat
     7441 cttgaaaact tagaaaaacg taaaactgaa gtgattcggc taatcgatga acaagggaaa
     7501 ctgactcccg agttagaagc agaaatcacc caagccgtga aaatgcaaca agtggaagat
     7561 ttgtatcgtc catacaaaca aaaacgacgg acaaaagcaa cgattgctaa agaaaaagga
     7621 cttgaaccac tcgcgaagtg gctgatgcag cttacagatg gagaggtgca atctgaagca
     7681 gaaaaatata ttgacaaaga aaaagaagtc tcttctgccg aagaagcgtt gcacggtgct
     7741 catgagatta ttgctgaaca agtcagcgat aatgcaaaat ttcggacttg gattcggtct
     7801 tatacgtata acaaaggtat gtatgtcagc aatgtcaagg atgagcaagc agatgaaaaa
     7861 ggcgtatatg aaatgtatta tgactttgca gaacccgtcc ataaaatggt ttctcatcga
     7921 atattagcta ctaatcgtgg agaaaaagaa gatattctga aagtattctt tcaagtagat
     7981 gaagcagcaa ttttagctta cttggatcgc caaatagtca aaaatcctgc ctctccttct
     8041 tcttcattcg tcagagaagc ctatcaggat agttataaac gctttattca gccagcaatc
     8101 gagcgagaac tgcgcaatga attgactgaa aaggcagatg agcaagcaat cgctattttc
     8161 ggcgaaaacc tccgtaatct tttgttgcaa ccgccactaa aaggtaaagt tgtcctggga
     8221 tttgatccgg cttatcgtac tggatgtaaa ctagcagtcg tagatgcgac agggaaagtt
     8281 ttagcaatcg aagttattta tcctcataaa cctgcagcgc aagcaaaaag agaagctgct
     8341 ggaccagctt ttatccaatt aattaataaa tatcaagtag atatggtagc tatcggaaat
     8401 ggtacagcca gtcgggaatc tgaacttttt gtggctgagc agttgaaatc cgccgaccat
     8461 aaaacctatt acgctatcgt caacgaagca ggcgcttctg tttactccgc tagcgaaatt
     8521 gcacgaaaag aatttccgca tctacaagtt gaagaaagaa gtgctgtttc tattgcccgt
     8581 cgcctgcaag atcctttagc tgaattagtc aaaatcgatc ctaaagctgt cggagtaggc
     8641 cagtaccaac atgacgtttc tcaaaaacgt ttggctgaac aattggattt tgttgtggaa
     8701 acagcggtta accaagtagg tgtggatgtg aatacagcaa gcccgcagct cttgcagcat
     8761 atatcaggat tgaataaaac aactgcccaa aacattgtca tttatcgtga agaaaacgga
     8821 gaattcaccg cacgaactca attgaaaaaa gtgccacgct taggaccaaa agcatatgaa
     8881 caagcaatcg gattcttgcg agtccctggt gggaaaaaca ttttggacaa cacaggtatc
     8941 catcccgaaa gttattctat tgcaaaagaa atattaactt cagtccaact ttcagaaaaa
     9001 gagcttggta cagaagaagc agtagaaaaa ttgacacgat tatccgtaga gaaactggct
     9061 gaaagcctat cagtcggaga agaaacgtta gccgatattt tagctgggct gacacaacct
     9121 ggacgagata tgcgtgatga gatgccagcg cccttattac gtacagatgt attgagtatg
     9181 gaagacttga aaccagggat ggaattgact ggaacggtcc gtaatgtcat tgacttcggc
     9241 gcatttgttg atatcggtgt gaagcaagac ggacttgtcc atatatcgaa actcagcaaa
     9301 aaattcgtca agcatcctac agatgtcgtg tcagtaggag atatcgtaac agtttggata
     9361 gaacaagtcg atacgaaaaa aggcagaatc agtttgacga tgctttcccc ttatgaagag
     9421 taacaatgag gagtaacaaa aattgacaca agaagaactg cagcagttag tagaagagat
     9481 atcattaaaa agcttccagc ttcctttcaa gcaccaagca atgttcaatc cacgcttacg
     9541 tacaactggc gggcgctatc atttaaacga tcatcattta gattttaatg cgaagctatt
     9601 tgaagagtca gacgaagaga cgattgcagg aatcatcaaa catgaacttt gccattatca
     9661 tcttcatcta gctggaagag ggtatcagca taaagatatg gatttcaagt atcttttgaa
     9721 aaaaacagga gggttgcgct atgcaccagc cttgacgaag aaacagataa agatggagta
     9781 ttatcgatgc caagattgtt ctgccacgat ctgccgcaag agaagaatcg atgtacgcaa
     9841 atatcgttgt ggaagatgtc atggagaaat caaatggatt gagacaaaaa gagaagactt
     9901 taatgaagca caaaaaatca gatgaaagga tagaaggcct ttggaaaaaa gtgagcagag
     9961 gaatctaaaa gactggaatc agctattaaa ttttttagcc gcacctgaag agggaaattt
    10021 tgaggaactg acggcaccta cacttatttt agctggaaac tgtcttccta tcttagctga
    10081 taaagcagca caaatgtatt taaatggcca agtagatcaa ttgtttttgg tcggaggggt
    10141 ggggcatgcg actagaatcc tttatgagaa ttttgaaaag caaggatttc attttgaaga
    10201 tggcatgagt gaaagtgaaa tctgtcgtca gtatctaaaa gaagtctatg atttgcccga
    10261 taaggctttt ctgatagaat cgaagtctac aaattctgga gagaacgcca ctttttcact
    10321 ggagattctt cattccttag gagctgtacc agaaaaaatc ttattgatga atgatccgac
    10381 actgcaacgc aggactcgag caacttttga gaaagtatgg caaaatgaac aaactatttt
    10441 cgcgaatgct gtgccatttg tgccggaaat ccttcacttt tctgaagaga tcatctttac
    10501 agcaaaagaa ctgaatcatc aatggcctaa ggaatatttc catgcgctag tattaggaga
    10561 aatggaacgt ctccatgacg atgagaacgg ctatggtccg aaaggaaaag attttattcc
    10621 tcacattgat atatcagagg aagtttggtc ttcttacacc agaattaaag agtcaataaa
    10681 aacggatttt tctcgtactt gaccatttta gcaagcgaat cctcctttcc aaataaattt
    10741 ggttgaaatt ttcaatcgtt tataagataa tgaggagcgt gttgaatgta atagctaaaa
    10801 gaatggacgc tagataagag aagaggattc aaatggaaaa tcaaaataaa ttgtatcatt
    10861 ttgttggtat caaaggttca ggaatgagct ccttggctct tgttttacat gaacaaggtc
    10921 taaatgtcca aggatcagac attgaaaaat atttctttac acaaagagat ttagaaaaag
    10981 caaatatcac gattctgcca tttaacgcag ataatgtaaa accagggatg acgatcattg
    11041 caggaaatgc atttcctgat tcacatgaag aaatccagcg agcaaaagaa ttaggtttgg
    11101 aagtgattcg ctatcacgac tttattggtc attttatcca aaattatacg agtatcgctg
    11161 taacaggctc tcacggaaaa acaagtacga ctggactgct ctctcatgta ttgagtggtg
    11221 tccgtccaac aagttatcta attggagatg gaacaggaca tggtgatccg caagcggaat
    11281 tcttttcatt tgaggcctgt gaatatcgcc gtcatttcct tgcctattca ccagactatg
    11341 caatcatgac caatatcgat tttgatcatc cggattatta tacaagtatc gacgatgtat
    11401 ttacagcttt ccaaacaatg gctggacaag tgaaaaaagc tatttttgcg tatggtgacg
    11461 atgcttattt acgcaaatta aaagcaaatg tgccgattta ttattatggt gtcacagaaa
    11521 acgatgatat ccaagcacga aacatcgaac gcacaacttc tggttctgct tttgatgtct
    11581 atcatgggga tgaatttgtt gggcacttca ctgtaccagc attcggtaaa cacaatatct
    11641 taaatgcttt aggtgttatt gcagtagctt atttcgaaaa actggatctg aaagaagttg
    11701 cagaagaaat gctgactttc ccaggagtaa aacgtcgatt cagtgaaaag atcgtagcag
    11761 acatgaccgt agtcgatgat tatgcgcatc accctgcaga gatcaaagca acgattgatg
    11821 gcgcacgcca aaaatatcca gataaagaaa taattgcagt tttccaaccc catacgttta
    11881 cgcgtacgat tgcattgatg gatgaatttg cagaagcact tgatttagct gataaagttt
    11941 acttatgcga tatttttggt tcggctcggg aagaacaagg aaacgttaag attgaagacc
    12001 ttggagcgaa aatcaaaaaa ggtggagaag tcatcaaaga aaataatgta tctccattgt
    12061 tagattatca tgatgcagta gtaatcttca tgggtgctgg agatgttcaa aaatttgaac
    12121 aagcgtatga aaaactttta agcagcacga cgaaaaatgt actgtaatac aattactgca
    12181 gtgtccttat aaaaatagaa agagggggag tggcaaaaat cttgccaagc cccctttttt
    12241 gcaacttatg ataaacggtg ttcaaaagct tgcatctgcg gtaataagcc caatcaaatc
    12301 aaaaacatga gaagctgttt tttcttggct gttcttatta tttgatgcag gacagctttt
    12361 tcacgacctc tgtaaactat aggaatctgt taaatcaagg gagcagaact tgccttttac
    12421 gctacttttg gtacaataat gtatgattaa aaataaactg gagggtttct atcttgaaca
    12481 taggtaagcc gagaaaacta ggaaaaacaa taaatgaaat cgaggaaggc gactcgttat
    12541 ccttaacaga atctattgaa gataaccagc ttttgctgta tttgggattg acgaatgatg
    12601 caaatccttt gtatatccaa catgactttg cacaaaaaac agaatatcaa cagccaatcg
    12661 ttccatcagt gatgctgatg gggatcatca caagtgcaat ttcaaagcat cttcctggac
    12721 caggatcaca tgttgtcaat ttttctgtca attttattga accggttttc cattatgaaa
    12781 cactgacttt tcagtttgag gtcataaaag tagataagat gaaggatgtg gtgacgattt
    12841 ctgtagaagc ggagaatacg aacgaagatc gtgtgttgga tgctgtcgtt atggtccaac
    12901 cgccacaagt tcctgaattg gaaatagcaa tcgaaagtga aggtgaattg aatgaataat
    12961 ccaagtacat caatgtcagg tatcaatcgt ttttatgcaa aagtttatgg atttttaggt
    13021 atgggacttg cccttagtgc agtcacttct tacttggctc tttgggtatt tcctttgcaa
    13081 ttagcaactt ttatcaataa ttttccacta ggctttgtgg gtctgtggat cgttgaactg
    13141 attttagtaa tggttctagg cgtaaaagca caaaagaatc cgagcttagc aatcggtgga
    13201 tttattgcct actctctttt gaatggcata acattagcgg ttactcttgc atactacgat
    13261 attggaacag taacgcaagc tttcttgaca gctactttga tgttcatggg gatgtctgtt
    13321 gtcggagtaa caacaaaaag agatcttagc ggggttggaa gagcaggaca ggcagcttta
    13381 atcggagtga tcattgcact agtcttgaac atcttcattt tgagaagtag cgtagttgag
    13441 ctgttcatct ccctactgtt agtcgtcatc tttgcaggga ttacagctta tgataaccaa
    13501 agcatccgta atatctatgt ccagacaaac ggaacagcac atagtggaat tgctgtattc
    13561 atggcattga agctgtattt ggactttatc aacttgttct tggcgtttct gagaatcttt
    13621 ggacggaaca actaaaaaag aaaaaaattc atcagttggg gctataccga attatttggt
    13681 atggtcccgc tttttctttt cgcattccgc aggattcttt gttagaatga ataagaactt
    13741 tacagtaagg agttaagaag atgacaaaaa ataaattatt actcgttgat gggaacagtg
    13801 tggcttttcg cgcattcttt gcgcttcaca attctcttga acgtttcaaa aatagaaacg
    13861 gtcttcatac aaatgcaatc tatgcattca atacgatgtt tgaaaatgtt atgcaaaaag
    13921 agcaaccgac tcatgttctg gttgcgttcg atgcaggaaa aacgactttt cggacagaaa
    13981 tgtatgcgga gtacaaaggt ggaagatcca aaacacctgg cgaattcaaa gaacaaatgc
    14041 catatatacg tgatttgttg acaggactag gggtacagta ttacgaattg cccaattatg
    14101 aagcagatga tattatcggt actttggcag aaaaagtaga caaagatcaa tttgatgtcg
    14161 tcgtgctttc aggtgatcgg gatttgactc aattagctag taaagaagta aaagtggata
    14221 tcactgtaaa aggtgtcagc gatatcgaaa gctatacacc agaacatgta gcggaaaaat
    14281 atgatgggtt gacgccaaaa cagattattg acatgaaggg actagccgga gatgcctctg
    14341 acaatatccc cggtgtgact aaaatcggtg aaaaaacagc tatcaagcta ttgaaacaat
    14401 atggctcagt cgaaggaatt tatgaacata tcgatgaaat gaagcaaagc aaaatgaaag
    14461 aaaatctgat aaatgacaaa gagcaggctt tcttatcgaa aaaattggcg accatcaata
    14521 cttcagcgcc tgtggatgtc tctatcgact cattgaagta tgaagggaaa aatctcgata
    14581 aactcgttcc gttttataaa gaaatggatt tcaatcagtt cctttctaaa ttgaatatcg
    14641 tagaagaaga agtaaaaatg gatgatattt tgtttgaagt cgttcatgaa ttcaaagagg
    14701 aaatgtttac tacggatatg gcgttgtacg tggaaatgat gggcgacaat tatcatacag
    14761 aggaaatcgt cggagtagcg tgggggacag aaaagaaaat ttatgtcacg aacgatctat
    14821 ctgtattcga aaaccgagcg ttccattctt ggatcactga tccgactcgg ctgaaaaaag
    14881 tatatgatgc gaaacgaact tatgttgctt taaaccgcta tactggaaaa acgaaaggaa
    14941 tcgattttga tgtcttgcta ggtgcatacc ttctcgatac gaatgaaaaa agcacagata
    15001 tcgaaggaat agctgctcat tacggataca acgatatcca atcagatgaa gctgtatacg
    15061 gcaaaggggc gaaaaaaggt ttaccagaag aagaggaact cttttttgct catttagcgc
    15121 gaaaagtagc tgcaatcaat gcgttgacac caaaattgag ccaagaactg gcagaaaaaa
    15181 accaagaaga tcttttccgg aaaatggaac tgccattgtc tatcattttg gcagagatgg
    15241 aaataagcgg gatcaaagta gatgcgactc gcttacaaga aatgaagggc gagttctctg
    15301 ctcgcttaag agagatcgaa caaaaaatct acgaagaagc cggcgaagaa ttcaatttga
    15361 attcaccaaa gcaattagga gtgatcttat ttgaaaaaat gggattaccc gttatcaaaa
    15421 aaacaaaaac tggatattcc acagccgtag atgtactgga acagcttcgt gaacaagcac
    15481 caatcgtaga ggatatcctc acctatcgtc aaattgcaaa aattcaatct acctatgtcg
    15541 agggactgct gaaagtgatc caatcagatg gaaaagtgca tacccgttat gtccagacat
    15601 tgacccaaac aggacgatta agctctgttg atcctaattt gcagaacatc ccgattcgat
    15661 tagatgaagg gagaaagata cgtcaggcat ttgttcctag agaaaaagac tggctgattt
    15721 attcttctga ctattcacaa atcgagttac gcgtacttgc gcatatctca aatgatgaac
    15781 atttgaaagc tgccttccta gaaggtcaag atatccatgc cagcacagcg atgcgtgtat
    15841 ttggaatcga aaaggcagag gatgtcacac caaatatgcg taggcaggca aaagcagtga
    15901 attttggtat cgtgtatggc atctctgatt acggactttc acaaaatcta ggaatcagcc
    15961 gaaaagcagc acagcaatac atcgatacgt actttgaaaa atacccaggt gtcaaagaat
    16021 atatggaaag aatcgtacgc gaagcaaaag accaaggcta cgtcgaaacg ctgtatcacc
    16081 gccgtcgata tctgccagac atcaattcaa gaaattacaa tatccgttct tttgcggaac
    16141 gaacagctat caatacacca atccaaggaa gtgctgctga tattttgaaa atcgcgatga
    16201 tcgaattgga taaacgatta aaagaaacag gtcttcaagc tacgatgctg ttacaagttc
    16261 atgatgaact tgtcttcgag gtaccggaaa aagaacttga atcattagat aaattggtga
    16321 aggaagttat ggaacaagct gtttctcttc atgtaccact gatcactgac agcagttggg
    16381 gaaaaacgtg gtacgaagca aaataaacat tgtttaagac agagcaatat aatgaaggtg
    16441 aaaagaaaaa atgccagaat taccagaagt agaaaccgtt cgtaaaggat tggaacggtt
    16501 agtagtagga aaaacgattc aaaaagttca ggtcttgtgg cccaagatca tcgagcaacc
    16561 agagacaccc atctttgagg cttctcttgt tggcgaaacc atccaatcca ttggacgtag
    16621 agggaagttt ttaatttttc atctcgatca ttgtgaactg atctcacact tgcgaatgga
    16681 aggaaaatat caatttacga aagaaaatac accaatcgat aaacatacgc atgtactttt
    16741 cttttttgag gatggaagcc aacttcgcta caacgatgta cgaaaatttg gtcgtatgac
    16801 aatcgtcgaa aaaggagcaa gtgcaactta ccgaggaatc atgaaattgg gacctgagcc
    16861 tttgccagat agcttcttat tagcagattt cgcaaatgga ctgaaaaagt cccacaaagc
    16921 aatcaagcca ttgctgctag accaacgtct agtgactggt ctaggtaata tttatgtaga
    16981 tgaagcatta tgggaagcga agatccatcc agaacaaccg gcgaacacac tgcgccccaa
    17041 agaggtagaa caattacgtc tatcgatcat tgatgttttg gatcgtgcaa tagaagccgg
    17101 aggtaccacg attcgcagtt atttgaatgc attaggagaa tcaggcggat ttcaagtagc
    17161 actgcatgtc tatcagcaaa ctggcaaacc atgtatacgt tgtggaacgc cgatcgtgaa
    17221 aacaaaagtg gcacaaaggg ggacgcacta ttgtccgaat tgtcaaaggc taaaaatcgc
    17281 aaagtaggat ttgttttagg tttgacgggt ggaatagcta ccggtaaaag tacggcagcc
    17341 aaagtctttc agtctcatgg atttcctttg atcgatggcg atgtgattgc cagagaaact
    17401 gttgagcctg gaacgcttgc tctgaggaaa attgtatcag tgtttggcca agaggtattg
    17461 cagcctgatg ggcaactaga tcgagggaaa cttgggatga ttgtttttcc atcaaaggaa
    17521 aaacggcaaa aacttgatca gctattagat ccgtttatcc gaaaagcgat aaaagatcaa
    17581 atcgcctctc taagttccaa tcatccttta gtaattgtag atatcccatt gctctacgaa
    17641 ggtcattatg accactatat ggatgcagta gctgtcgttt atactacgcc agaaactcag
    17701 cttcagcgtt tgatgaaacg taatcaactg acgctagaac aagcgcagca gagaattagt
    17761 agtcaacttc caatcgaaga aaaaaagcag cgtgcggata ttttgttcga caacaatgga
    17821 acaaaagaaa aacttgtggg acaaatcgaa aattggcttt ttgctaatcg ctttctttga
    17881 gtatctgtgt caattttgct atcctgagta tatagaaagt gagggatagc gatgggatca
    17941 ttaaaaaatc aaaaggataa agtcgtaggt aacgcaaaag aaaaaatcgg cgagatgctc
    18001 aataaagaaa atctaatcga tgaaggtcgt acgcaatcag aaacagcaga agaaaaagaa
    18061 aagcagtacc aagcaagaat cgatgaaata gaagaccagc aggcagaaga agaagcgaag
    18121 cggcaagatt tgactcaaga acgaaaaaat ccgacacctg atcgtagtaa aacaccgctc
    18181 ccagaaagtg accacattcc cgatgagcaa aaaatcgagg aacagcgaat gaaacactat
    18241 acaggaatcg aagagaagtt ataaaatagt aaaaaatcga gatgtgactt gaagcagatg
    18301 agaaggtgtt catctgcttc aagttttttg tgctagatga ctaaatcagc ttttgtgtaa
    18361 gttatttctc agtaatcaag gtgatcagta ttggaaaatt gaaatttagt aaggacaggg
    18421 gacacaatta cgcatgaaag tagaaaaaat tgttcttata tccgtgtttt ttgggtagga
    18481 cagtcgcgtt tgtgatttgt ttcgtgttat aatacaacta gttgtaaaga aagacacatc
    18541 ctttatataa aatgcgatgc aagaggtgag acaaaatgag atgtcccaga tgtcaacata
    18601 ataattcacg agtaatcgac agccgtcaag cagatgatgg acgtgcgatc cgtcgccgtc
    18661 gcgaatgtga gaattgttcg ttccgattca ctacatttga acgaattgaa gctgctccgt
    18721 tattagtaat caagaaaaac ggggaacgcg aagagttcaa tcgcgataaa attttaagag
    18781 gactcatccg ttcagcagaa aaaagacctg tagctatgga acaaatggaa caaatcgtca
    18841 accatgtcga aaaccgcgta cgcagtctcg gagaaaacga agtatcgacg aatctaattg
    18901 gtgaatatgt gatggaagat ttagttgatt tagacgaaat cgcttatatt cgttttgcaa
    18961 gtgtttatcg ccagttcaaa gatatgtctg ttttcttaaa agagttgcaa gatatcgtgg
    19021 ataaagcaaa agaaaataat aaagagaata ataaagaaaa caattaagaa acaaaaagga
    19081 ggcatttcct tggaaaatgc ttggaaagag cttcaaccaa aaaatattta ccaaggaaga
    19141 aaagcggctc cgctgagaga agacagcaag aacgccttgc tgtatcttta tcagccacta
    19201 atcggcggag aagccttgag tatctatttc accctgttat cagaaatctc tcaagaatct
    19261 ggcaaaggtc ctgaagggat gcatgcagat ctgcttagta gtctaggctg cggtatcccg
    19321 caattttatg atgcaagaaa aaagctagaa ggaatcggct tactggatgt ttattttaaa
    19381 gaagatagtg atctgggacc tcgttttatt tatgagctgt tagaaccact cattcctaaa
    19441 gcatttttca aagactctgt tctggctttt cttcttctgg aaaaagttgg tgaacgacga
    19501 ttccagaagc ttacccaatt ctttgaacct aaaaggcata cagcagaggg atatcaaaaa
    19561 atcacaaaaa aatttttaga tgtttatcgc ttcaatgaag cagtgtacgc tgctaatcaa
    19621 gaaaacatcg aatcgctgaa taaatctttt gaagaatctg aatcagtagc attacttgaa
    19681 gcagattcga cattcgattg gcagtttttg aatgattggc tggcaaaaaa acatattgca
    19741 agtcttgatg atccaatcat caaacaagtc gacatgtatc atcagcttta cggtttcgat
    19801 gaattgacac ttggcgaact gatcagtcaa tcttatgact ttagtgaaca aaaagtatct
    19861 gaaaaagaac tgcaaaaagc cattttggca atgcagagac gtccggtgaa gcaaacaaaa
    19921 gaaacagttg cggtttctga aaacagtaat gaaccctcgt caaacgaaca tttgacaaac
    19981 gcagcgcttc agctgataaa agaagcacag agcattccac cgatgaaata tctggaagca
    20041 atcaagtcag aaaaaggcgg atatgtttct aaacaagaaa actggttact gcaagatctt
    20101 gtttctcaat caggtctttc cagtagcgtg atcaatgttt tgctgaatta tgtactagtg
    20161 atcaagaata atgctagctt aaatgccagt tatgtaaata cagtggcaaa tgaatgggca
    20221 caaaagaaaa tcgccacagc agaagaagcg atccagcaca ttcggcaaat aagtaatcaa
    20281 gcaaaacaat caaaacaaaa gaagcaaaca aattatcaaa ctggcaagcg aaatgttcga
    20341 cgggaaaagc ttcctgattg ggtcaaccag ccaaaagatg aaaaacagat cagcagcgag
    20401 aaaaaagcag agattgaccg ccgttttaaa gaatacctgg caaaaaagga gggtgatatc
    20461 tagtggaaga cgtaggcaaa gaattgaaga ggatcatcag caaacgcaat tatcaagaaa
    20521 agtatgctga aatgatcgct gaagtcttaa atgatgcgga tgttcaagct tttctaagcg
    20581 cacaccaaga agaattgaca caagcggata ttgaaaaaag ttacgctaaa ttgtatgaat
    20641 tcgtgcaaga aaagcgtaaa tatcaaaaaa acgatccaac gatgatcgct cccggctatg
    20701 agccgaagct gacgttgaat tttcattatg tggatgtcac ttatgtacca acggaagcat
    20761 tgttagcacg gcaaagacaa gaagaaatca gaagccgagt aaaagcaatg gatatgccaa
    20821 aagatattca atcggcttct tttgaaaact ttgaacgtac agatggacga ggatatgcga
    20881 gcttagaagc cctagatttt gtagagaaat atactgctga tccaaaaggg tatcataaag
    20941 gactgtatct agtaggaagt tttggtattg gaaaaacata tttattagga gcaacagcga
    21001 gagaattagc gattgctgga ttcaccacga cgctagtcca ttttccgaca tttgccgttg
    21061 agatgaaaca ggcaatcgga aaagatcaag tggcagaaaa gttagatgca gtgaaacgtt
    21121 cacctatttt gatgatcgat gacattggtg cagatgcgat gagtagttgg atacgagacg
    21181 aagtattcgg tgttatcctt caatatcgga tgcaggaaca gttaccaacc ttcttctcat
    21241 cgaattttac aatggatgaa ttggaacagc atttgtccgt cactcaacgt ggagatgaag
    21301 agccgctaaa agcgaaacgg ataatggaac gcatacgtta tttgacaaaa gaaatcgaaa
    21361 tgactggtcg caaccgacgc aatggttgaa cagttgacaa gtccaactga catttgacct
    21421 agtagtaaaa gcaggtcagc gaatcattat atggacagaa atgaccggag acaatcaccg
    21481 caacaagtaa tgcagaaact taaacggagg attttttatg agggctattt tttctagtat
    21541 atctgtagtt ggtctatttt ttcttttagc aggctgcggt agcgcagata gcaacacagg
    21601 ttctgttgat tcgattgatg cgggtcaaac agtaaaaaca agcagtacga aaacggagag
    21661 acaaagcata tttgtcggaa cgattgaaag tatcactcaa gtagaagcag aagaagaaac
    21721 gcttcagttg aaactcgtcg atgtcatggc caaagaagat ccagcgaata tgggaacgtc
    21781 attcagcaat gacggagtga tcttaaatgc tactgctgaa aaaataagcg tggacataaa
    21841 tgaattgaaa atcggtgaca aagtccaatt tacattagtt gagatgccga tcatgacgat
    21901 gtctatccca ccgcaagttc ctggagattc gattattgat gtttcattga acaaataacc
    21961 aataacattt tttcaaaaat aagaaaatgt tgttttatag aacgaaaagg tatatttttt
    22021 aaggagatat ggga
//
LOCUS       DAZKKZ010000051        21094 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.052, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000051 DAZKKZ010000000
VERSION     DAZKKZ010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21094)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21094)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21094
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.052"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            52..561
                     /locus_tag="ACG8LA_002027"
                     /pseudo
     CDS             52..561
                     /locus_tag="ACG8LA_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338071.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            562..879
                     /gene="traE"
                     /locus_tag="ACG8LA_002028"
     CDS             562..879
                     /gene="traE"
                     /locus_tag="ACG8LA_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV conjugative transfer system protein
                     TraE"
                     /protein_id="HFQ0204321.1"
                     /translation="MLSLKDICHYGKRCTATEKITKKLSTGQSKTVVQCKKYIIQKDK
                     VSEEMIYYIGKQKQIILKDPIPLKELYPTIKHVYDQNGVLIGRRKNGVLRCTAKGMGR
                     LIS"
     gene            1498..1839
                     /locus_tag="ACG8LA_002029"
     CDS             1498..1839
                     /locus_tag="ACG8LA_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5406 family protein"
                     /protein_id="HFQ0204322.1"
                     /translation="MKNYDPNIRLGTHTIKVSFQRWDYKGFVTFRRGGNCKGLDVLAL
                     NEDDLYDQTLTDNPIGFGLLPEDDEGNEWFKMTLMNDNGDELSVEDTWSYLSDYIVSV
                     EIIEFVADKEE"
     gene            1858..2148
                     /locus_tag="ACG8LA_002030"
     CDS             1858..2148
                     /locus_tag="ACG8LA_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204323.1"
                     /translation="MKFFEVKSPYYYALIAAKNEEECAELYEQVVTDIENREEFIRCL
                     HELNRNEAIQEDAKKISEETLQPIGMEEATKDIFTIINEQKSCVLSIDSTLV"
     gene            2340..2573
                     /locus_tag="ACG8LA_002031"
     CDS             2340..2573
                     /locus_tag="ACG8LA_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204324.1"
                     /translation="MARPVLDAMDMDTLTKGRYVQLLARGYSPKDVFKALSKGTDMEK
                     ERLRKEFDYWREHNGIKDLKPARPVIRRKKLKK"
     gene            2640..2907
                     /locus_tag="ACG8LA_002032"
                     /pseudo
     CDS             2640..2907
                     /locus_tag="ACG8LA_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322851.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            2993..3664
                     /locus_tag="ACG8LA_002033"
     CDS             2993..3664
                     /locus_tag="ACG8LA_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HFQ0204325.1"
                     /translation="MKKWLFGFLGVALIVFCSVFGYVSYQKHEGDVFKQNIEKKMPVD
                     QINAHAKSYKEDATNVNNDMSLGQMLSIQKEAIEMGVNKQVFAQIQIPALGLALPIFK
                     GANQYTLSLGAATYFYEDAEMGKGNYVLAGHNMEMPGVLFSDIQKLSLGEVMDLVSND
                     GVYRYKVTCKFIVSEYFKLIDGVPEENSFLSLPKKGEKPLLTLFTCVYTSQGKERYVV
                     QGELQ"
     gene            3717..5693
                     /locus_tag="ACG8LA_002034"
     CDS             3717..5693
                     /locus_tag="ACG8LA_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaA isopeptide-forming pilin-related protein"
                     /protein_id="HFQ0204326.1"
                     /translation="MAINRYVKKAGMLVGMLGIIAGCFQGYRAYAEDVTQKTPPEKVN
                     ITVHKLMYDQGTQLNVDIDGIKNDGYTHDQYPTGVTKYNKADYGDVEFTLGNITDQVL
                     PTEDSDLTNAKVDEIVKDVEDKGSNSEYVKNATNKITSAVDENGEITFADQPAYVNSK
                     GNVYVVYESKSAAGLVTQKAKPMVVIAPMTDNTGSGFLKDIHLYPKNIVSKLSFELTK
                     FGDDGTAQSKQTPLKGAKFELYKGEPGKGTKLGDLVSDDQGKLTATDLTLGKYYFVEV
                     PSEVVVGSDKEPTADQYLLGADARNDAHNKLTFEITNDGVTSDLKASYVNYKAPVIDK
                     TVTNGTGQEHSFQIGDAVNYQGTIHIPTDIAGGADGITVNGVKSETSPYSVFKWGDTA
                     GQGLSYVAAKANIKVTNKDGSVVLKENTDYKIQNSENGFVIDFIVNNGQVSDTVASLH
                     GQDLQMTYNMYVNDSAAVANPLTNSVDFVYNNNPFNQEEHHEKTKADVVTYGAKFLKV
                     DSGLFGTGIKATPLEGAEFAAKNAEGKYYGGLVDTDKDGVKEAVWVDDVANAAILKSD
                     KEGHFEITRLTEGEYSLEETKAPENYQKLTKEISFKVDKDSYKEENRITIKNNQKVSV
                     PMTGSNGFQTYVLISCLLLGAGALSAVVYFKKKA"
     gene            5708..6460
                     /locus_tag="ACG8LA_002035"
     CDS             5708..6460
                     /locus_tag="ACG8LA_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HFQ0204327.1"
                     /translation="MIIRKPKKKRIMGKWIIAFWLLSAVGVLLLMPAEASVAKYQQNQ
                     QIAAIDRTGTAAETDSSLDVAKIELGDPVGILTIPSISLKLPIYDGTSDKILENGVGI
                     TEGTGDITGGNGKNPLIAGHSGLYKDNLFDDLPSVKKGEKFYIKVDGEQHAYQIDRIE
                     EVQKDELQRNFVTYLEPNPNEDRVTLMTCTPKGINTHRFLVYGKRVTFTKSELKDEEN
                     KKQKLSWKWLLGSTVFLSVMIIGSLFVYKKKK"
     gene            6476..7237
                     /locus_tag="ACG8LA_002036"
     CDS             6476..7237
                     /locus_tag="ACG8LA_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pilin N-terminal domain-containing protein"
                     /protein_id="HFQ0204328.1"
                     /translation="MRNRKWLFVCAAALFTFTAYTQLTVADSQESTDSTEQTIQTSDS
                     SAIQSSDETVDSSTVDSSEEPKIAEDDQIVKQTIHVQKIISSEQLDNQGQKLEKQEGV
                     NGAKFSVYDVSDILQKMDVKDLTTDQIESQLKDRVKKLSSDQLKLISNGETKTIDQQT
                     GVFEFSVEVQANQKQAYYIVNESSPENISNSEDILLLTPVSDKNGEFLKDVWIYPKSE
                     ASQPKEEVKKIVSTGVKKNFFENCWDFVTHLFSRD"
     gene            7250..7510
                     /locus_tag="ACG8LA_002037"
     CDS             7250..7510
                     /locus_tag="ACG8LA_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204329.1"
                     /translation="MKLIKLLLFNLSCLTAVFLYCGLLFSQLSILPSYQLYLMRILNI
                     PAASMPLDIMEKLIRNPLFTTINLIVIVGISLVIYKKEGMKG"
     gene            7507..9597
                     /locus_tag="ACG8LA_002038"
     CDS             7507..9597
                     /locus_tag="ACG8LA_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HFQ0204330.1"
                     /translation="MNFKHSWTRRLKYVFPIMMMLGTLFGLKTANVFAEKVIVDPSNP
                     IQNVKNNFIIPKDVPNAKTNITVNGASKVYKYHVDANKGGFTDDYVGLVEGNKNIRYP
                     SFQKEYGETNLVLEGVTTNTKVNIDYGKIGTYNGKKVNIKLVLSNIHLYSDTLPWNLL
                     DNNYTKTHFRDDGYKNTNGAMSKSKKRTVLWISDNLFSGIVYHSTQMNVQLVATYEDG
                     SPVQFSGDTFISFNSLNPAGGKSTDLKGEYTHYDKMNTTDWYVRKDTVLSEFKSFYNN
                     LNVVGGHPGGSSKLTQADNDFNNLHDKLGDPKFGQGTVSFKISEANPTFVIGSSNVQT
                     WFTLSSATIFSVVPDQPEKTGVDKNGNNVNDNMLQVGDTIQYRIKQKVNRLGVDLLAV
                     YDRFELIDNLPKEVDYVDAHVESGTNKKFDVSGEVTYDKTKHQVKYAAKADTLKNRMK
                     YNGETYELVINVKVNELANQNSVAKNQGTSIINKVEKDTNIITVYFPKIPVKEVQQNG
                     KDVNGRNDGKKGTPTAPLNAGSEVQYLVTQKWHTKGVDAASDHYKQFSIQDPIEARLT
                     YKEVSAQVIDKSKGKDITSEGTLTYDSNLRTLKWEASADFLSNNLLDGREIQLIFTAK
                     TPLQSEKNIDNQAVVAVDNVSNKTNVVTIGVDPNLPQVIVPKTGSTHLVTISAVSLLL
                     LVLATFSYAVLRYI"
     gene            9624..10088
                     /locus_tag="ACG8LA_002039"
     CDS             9624..10088
                     /locus_tag="ACG8LA_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204331.1"
                     /translation="MKKLIIVVTSLIAMIVILVGCSNEKNKQTNQDNGVLKSGTMWKE
                     EVGGLVYNLKIIDETTWEYSESVWHPDPVQITVKRQKDYKGLERYKIVDSAGVREFIN
                     KSDSLFIVVPYEKNGVKKIIFLGSSKDEKRTKEKLIHDGSQSNKYKLQKTSE"
     gene            10085..10327
                     /locus_tag="ACG8LA_002040"
     CDS             10085..10327
                     /locus_tag="ACG8LA_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5415 family protein"
                     /protein_id="HFQ0204332.1"
                     /translation="MIASLFICPEGGITVAKAKTPFEKAASKILERRGVSETQWKQEV
                     LEKAQFDLLRGKDKDLEGYIYQREREKLVFDEIIKH"
     gene            10345..10647
                     /locus_tag="ACG8LA_002041"
     CDS             10345..10647
                     /locus_tag="ACG8LA_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204333.1"
                     /translation="MFESITMNFLTQPKVVAAVDIFRALQTAATSLKNNLMIFAAAAA
                     VASIVIGGLFFLFGRRGAENGKMHVGYVLMGVGVILAAASIVVSLFGLFGQTPQGL"
     gene            10717..12777
                     /locus_tag="ACG8LA_002042"
     CDS             10717..12777
                     /locus_tag="ACG8LA_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204334.1"
                     /translation="MYFTIAGNTKTDKELIKKATKEVGKRTSFLPKTIKYSVIETEEQ
                     LHVLGKVLEHESRSSVKLTLTLHDTEGKIEKAGTEYVFGPLDYQISEGFYPTLMDLIR
                     LDVFKETDETMSVEESYRNEKLLQVLEEELESDQRKVNQGSEVEVNEEVPWERPIFPK
                     KESKEKETVYVDEQADIPTQKSIFEEENDVMGQLEVDPFEETMEDEETAEVEVDPVEA
                     NEESTWTEGDSQEYIEPLISEEVEKNEIEIQKATVFDYILDQYPPEHEWMKEKNKLFL
                     NELYSKYQLPQTYQAFLESKEELISQGKGTLLEQLESVQSTNWHELAQEDLLATFEER
                     QQETDQEINEYATEQSSNWEKAKEELNKEEQRVIEEEVQKIKERYEKKRDNAYSLCVA
                     KINNFTQTNQEALSKEKENLLKERIKERKEEFYRGLRTDKLKISKELNEQLNKLYQTT
                     TEVLMEKHEQIQQELQVQIPKWKKEYEIQQQELKEQEEKQRQKEKEREQLELKKREQD
                     LAEQQMAIEKQRLNQEKEKEAARKERQEQMDTLRQAQLNYLAQPQPTPSVAAVQTPMN
                     NQTNLTPSPQRSFNGWMVGCIASLSLLLGGGTVFAFNHINQFSQADSVATTASIKEEA
                     REQARKEYEQQLEELLNRTNQSTTESSMENSKESDPSKAKEGSSDSTVQSNTSESSES
                     NEVK"
     gene            12777..15386
                     /locus_tag="ACG8LA_002043"
     CDS             12777..15386
                     /locus_tag="ACG8LA_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirD4-like conjugal transfer protein, CD1115
                     family"
                     /protein_id="HFQ0204335.1"
                     /translation="MRVRETTRRKDKRFNLEKNRYLSHFYRYTPSGEELPEKHDKRIS
                     QKIFYSGLAYLPLNYVVTRIPEAFHRFEIIPGSLQGVKIFQLQEMPQLFHFDSTGFWN
                     PLTPTTSLGTRLVVSTICVVPAILMGLKMDMWFRPLADGQKGDNRLKTLKEIQQIYPQ
                     IPESKGGFPGYGGIPITHYKKYWYIQTDTVNTCIIGTSRSGKGQIEVLATIDNLSRAE
                     RQSSMVVNDPKTELYVASKDELEARGYDVYAFNITDPLQSMSDNPLALIVKYWKRGDI
                     DTATQLTNTFTNTIYYDANASDNKYFNENAQKAVNALIFALLEQADQTGDYSKLTPNN
                     LVELLSEIGGFNYQDPENDYKQLNALDEFMNQLPPGNIAKKQYGATKIGSDKAKGNIL
                     STAITGLNPFTLTKIAKMTSQSTIDYKSIGFPKYLDLKLHESLLNQRIVVEFYHQGKK
                     FHEERVKVGYRGFCEINFDCHLEQGDHVCLKYDHQGKEYVAWYEFSQRVLKDEEGNIV
                     YRKKREETHLPELEKEAVLTLDEDKSNLLVESIRMHYTDKPMAIFMLTPDYDPSNHII
                     VSIFLSQLYKELSTQCVKTKGDKCHRRIHFILDEFGNMPPMDNMEGIMTVTAGRNMLW
                     DLFIQSYQQLYAKYGEQNAAIIKENCQTHIYIMSTDDNTIEEFSKKVGNKTVEQENST
                     TNLLGMNTHINRNVDSDRILTPERISTFLEGETIVLAPLKRQDLKGHKIRPYPIFNHG
                     ETNLPYAYQYIEDFNPSWDINDIDIHCTHADLDLKALQIDYDYFLPDEYARNLYHGLH
                     DQLEEKNEENMFYKIVQSLENETAQKLLIQFYEEQATDRLQEYVEKLIKNEEISEMIG
                     KRLLLEAEKAVKE"
     gene            15383..17914
                     /locus_tag="ACG8LA_002044"
     CDS             15383..17914
                     /locus_tag="ACG8LA_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pLS20_p028 family conjugation system
                     transmembrane protein"
                     /protein_id="HFQ0204336.1"
                     /translation="MIIGGIFSGIADWWSGLFGEGDANPKTVTKVLQDYGNYLQYQDV
                     FSWIWNTFLWGLIKGLYNLNTLLEKTIYQSFDLKDLLNAAGVNALFQSLISKVLALFC
                     VVTLIYLGLKFFMSKHPPKVKNILVNLFMAMILIFGGSSLIDEGLNISKSFYGDVTAA
                     NKADKTGSPAFQIIQNNVIDVSTLLATDPNKVESLPTDKRNALTAKNFKTANINGIIT
                     PKQAKEMADKDKSGLSDLQKDRLRALQYRLELDDNGKEIPVQISDEGLAKYVYTSGYR
                     RYSSKPGIILAGESSLAVAYLFILFTIVTCIIELVFKKFYLVIAASTDFETGQRMKSA
                     IEDISQSFLLLAFTILELRIYTLMLSGIGDLHAAGKINGFLYVVALIVLTIALFKGSQ
                     SVTKIFGVDTSLKNGSNSLLSMFALGNIAKNVGSGAKNLASAGKSGLSHLNDIRKNGF
                     GHRKDVTPDNGEEQSDDKATTVPNSKKTVSEMFGKAKNGVSKAAEGLGYVNERGLKGT
                     AEDLTEKAKDTLEEKLDGTRAKELAEAVKNPSEALEKQKEKASEVKEGLKDAYGEGQV
                     NAAVKANTTTEKENQEGIVIPSVKDHQEALHSNENSIEEKNSIEERNSEEGKNGQLPK
                     TDPEQYRYKPNSDLENEKRISDLSKVNQEDKAENEGQLPKTDPEQYRYRSVNSENEKR
                     ISDLPKRNQEVQTDEDSIVLPNDNGIEVGTEKSTKIGLPKAQNLPMKDSRLNQFKEND
                     QSFVHQSTAGTVQMKPSRLPENGNLTTVSYNLSESGETGNASVQNVVTREAAPKPIQN
                     VHTGYKPANVAFTAPTKINVTRETKNRNNALKEQLLRDIKQDIKP"
     gene            17964..18296
                     /locus_tag="ACG8LA_002045"
     CDS             17964..18296
                     /locus_tag="ACG8LA_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204337.1"
                     /translation="MDKYINMKNPPRFSGEWKFFAFFFLDLLTLGGCFFWAKMVNNLV
                     HLPLFFALLNYGLWIAIALVIVWRPYNNPGQRQIFAIIESIFFADKNHYHALDPNRNY
                     HGTYKEDE"
     gene            18297..18890
                     /locus_tag="ACG8LA_002046"
     CDS             18297..18890
                     /locus_tag="ACG8LA_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204338.1"
                     /translation="MRVKGQNSVERKSILQFGKPEERSILDLFPYKSCTEEGVLITRE
                     DHFQRYYRVVSTDVEGLNEQEKLERMNQLTTVMRTYVPTIKLVSLTTETDLTEQIVQK
                     RQLLDKNRMEQSLGRNLQRLKKYEKKLVEEIQELKRAEQERPDLSFFFVIEGKTIKDL
                     QTRNRQLMRSSGILGLKPLYKKELIKILYRMNNMNDE"
     gene            19053..21077
                     /locus_tag="ACG8LA_002047"
     CDS             19053..21077
                     /locus_tag="ACG8LA_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirB4 family type IV secretion system protein"
                     /protein_id="HFQ0204339.1"
                     /translation="MLEAIKTAFSPQNDQKVLDPLKQLGNREIEILKSKGYDLDFLKQ
                     VMPQGGLNFDEEYVTYGNGYSRCVTVYHYTKNPTLFWLANLMNNPHTVATLDVSTDEK
                     QKVIDQINRALDELNDRSDNERKATDRNKSAEEYLELAEYARKLTSNGEISKQVKVRV
                     HVYGNTIQEVDERAQELIENLKGMDYRAVTYLHKTKRDWQSMFTMFDEQAEWFGNIKG
                     QSLPSLNIGGGFPFHHQTLKDPGGTQYGETMTGGPFVWNATYKNSVRLSTNTLLLGMM
                     GAGKSTVLKMIAEAHLAAGDFIWGFEKGKDFIPFLKEYNGIMVRLDGSDGMINPLEIF
                     ATRTYDEASSLYDDGSVKDLKINEAASYQTHLDKVVYQVQLVSPQLKGTMKAEFKTYL
                     NRFYEEYGTVPRGFTSSNSRSNTETQVTGKDPEAYPTFKEFLDFLGQLELPGASQEKK
                     NRKEEMESIVESLCETYGMIFDGHSTIRHLDQQQLVFFDIDSITGLDRGVQQCQMYMA
                     MTLIWNQALIQGRRQRRLIKEKQMEEQDFKRFLAMIDECHNAINPDFIETVNYVTNFQ
                     REMRKVEAMTVLATQSPQEMVPENMSSDNFSKLKKVFEFSSTKIFMRMDESILRHIEG
                     LVGKSMTNSELESIPQQNQGDAVINFGSKETIRVHFSPNKRQLKLFDGGK"
BASE COUNT         7829 a         3270 c         4312 g         5683 t
ORIGIN      
        1 tttttgagcc aaaagtaagg aattacaaaa agagaaagaa gagaaggaag aatgaaaaag
       61 gtattatttg cggttagttt agttgttaat atagcactag caggaggatt attttatacc
      121 attacagaaa tgaataagct tgatgaccaa cgggaaagct tagcaatcag taacgaacaa
      181 tacaaaagga agctagatta agctagcagc accaacgtgg acactcaaga agccgtagaa
      241 tcctctacaa ttgtttatag caatgaatcc agtgaaaccc taacaaattc ggaaagaagc
      301 acagctccag ctacagaaac tgtttctcaa aaagctacta taacaatagg aagtaaagta
      361 ttcacgttta tagtaaatgg cttgacaata gaacacgatt ctagcagaac aggaaaaatg
      421 accgagcttt ctcacgagtt tccagtgatt gttactactc ctagtgctac ccttaacggt
      481 atattggtgc aagacaacaa tgataataat tgctatataa tggtagacgg tcaaactcta
      541 tacagaggaa cataccaata aattttgagt ctcaaagata tttgtcacta cggtaaacgg
      601 tgtaccgcta cagagaaaat cacgaagaaa ctatcaactg gccaaagtaa aaccgttgtg
      661 cagtgtaaga aatatataat ccagaaagac aaagtctcag aggaaatgat ttattacatt
      721 gggaaacaaa agcaaataat tttaaaagat cctatcccct taaaagagct atatccaaca
      781 atcaaacatg tttatgacca aaacggtgta ctgattggtc gaagaaaaaa tggagtcttg
      841 cgttgtaccg caaaagggat ggggcgttta atcagctgaa ttgatcattc tcataacttg
      901 tattttatcg tttttcgctt gcttgaaaat attgtcgaga cttctaaaag aacttagaat
      961 cattagaaaa ataaggagta gacttgatct atcaacaatt tccttcgggg agtgacgggg
     1021 tagattttta cgattggtaa cgtaaaaaat tggtcaatcg agtaaatgcg cttgtttgga
     1081 tagtggtgaa atgaatttgt gtaaataata tacacagagt aaacaagagg gaatttagag
     1141 gttagacaag ttagaatagc gcctagatta atcatgagca gctactaagg gatctaggct
     1201 ttgacgcaaa ctcatggaat aaggagtagg tcttctcgta atggggagga cgcacaagaa
     1261 attgtgtcgt gtgctgcagt acatgtagat acttgcgagg acgttggtca ttggatcaat
     1321 cgagcattta ccgctgtcta ctagggtttc tcgtttcgga cgccataaac gagtcgatat
     1381 tttttatgta tttttaagta aacgaaaaac gataaaatat gaacgagtcc tgaataaagt
     1441 gaaaaaattg atataaaaca tagagaaaat gaaatttacg taatggagga atgacaaatg
     1501 aaaaattatg atccgaatat acgattgggc acacatacta ttaaggtttc tttccaacgt
     1561 tgggattaca aaggttttgt gacgtttaga agaggcggaa attgtaaagg attagatgtt
     1621 ttagcattaa acgaggatga tttatacgat caaacattga ctgataatcc aattggattc
     1681 ggcttgctac ctgaagatga tgaaggtaat gaatggttta aaatgacgct tatgaatgat
     1741 aatggagacg aattatctgt tgaagatact tggtcatatt tgagtgatta tattgtcagc
     1801 gttgaaatca ttgaatttgt agcggataaa gaagaataaa aactggagga ataaattatg
     1861 aaatttttcg aagtaaaatc accatactat tatgcgttaa tcgcagcaaa gaatgaagaa
     1921 gaatgtgcag aattgtatga acaagtagta acagatatcg aaaatcgtga agaatttatt
     1981 cgatgtttgc atgagttaaa tcgaaatgaa gcaattcaag aggatgcgaa aaaaattagt
     2041 gaagaaacgt tacaaccaat cggtatggag gaagctacaa aagacatttt tacaattatt
     2101 aatgaacaaa aatcttgtgt attaagcatt gattctacat tggtttaata gatccaagat
     2161 tctataattt ttttcaaagt aaaaagaaat taggtaatga ttctcagacc aattacttag
     2221 gaaaataacc atacaaatta gattttacag ataaaggatt agaaggaatc acggcgatta
     2281 ataaaaaggt agtattacct taggcattga gtaaggaatt tatttaggag gaaaattaga
     2341 tggcgcgacc agttttagat gcgatggata tggatacttt gacaaaagga aggtatgtac
     2401 agctgttagc tcgtggttat tcacctaaag atgtattcaa agccctatct aaaggaacag
     2461 atatggaaaa agaaagatta cgaaaagaat tcgactattg gagagagcat aacggaataa
     2521 aagatttaaa accagcacgt ccagttatta gacgaaaaaa attgaagaag taagaccaaa
     2581 gcgtatggcg tacataggct tttttatttt gataaaaata atgaaaggaa ggaaaactca
     2641 tgaattgtaa agaaatcgaa aatagaaaaa aagtgtcgaa agaaatggaa gaaaagttac
     2701 taaaaacaat gaaacaaaaa caatgaaaca aaaacaatga aacaaaaaca ccttaaaaga
     2761 ttatctgtcg cgcaatatat caatgatatg cagttaacag gaaaagagaa agcttgtttg
     2821 ttaggttcaa tgaaaaactt tgaacagttg agacgaactt atgtgaaaaa aagttctaat
     2881 tgtcaactat tgttagaagt ctcatgacat tcattaatag aattcatttt taaaactttt
     2941 tctatggaaa tgagaaaaag tttttttgtt ttgtctgaaa ggaggcagat ggatgaaaaa
     3001 atggttattt ggttttttag gagtcgcttt aatcgtcttt tgcagtgtgt ttggctatgt
     3061 tagctaccaa aaacatgaag gagatgtgtt taagcaaaat atagaaaaaa agatgcccgt
     3121 agatcaaatc aatgcacacg caaagagtta taaggaggat gcaacgaacg tcaataatga
     3181 tatgtctttg gggcaaatgt tgtccataca aaaagaagca atcgaaatgg gcgtcaataa
     3241 acaagtattt gcacaaattc agattcctgc acttggttta gcattgccga tttttaaagg
     3301 ggcaaatcaa tacactttga gtcttggagc ggctacttat ttttatgagg atgccgaaat
     3361 gggcaaagga aactatgttc tagcaggaca caacatggaa atgccaggtg ttttattttc
     3421 agatattcaa aagttgtcat taggggaggt gatggactta gttagtaacg atggcgtcta
     3481 tcgttacaag gtaacgtgta aatttatcgt atctgagtac tttaaattaa ttgatggcgt
     3541 tcctgaagag aactctttct tgtctttacc aaagaaagga gagaaaccct tattaacgtt
     3601 gtttacttgt gtttatacgt cacaaggaaa agaaagatac gtggtacagg gagagctaca
     3661 ataacaaggt tgtaatcaac gcgagtcgtt gaaatatgaa atgaggagag taaaaaatgg
     3721 caataaatcg gtatgtaaaa aaagctggaa tgcttgttgg aatgttagga atcattgcag
     3781 gctgctttca gggatatcga gcatatgcag aagatgtcac gcaaaaaacg ccaccagaga
     3841 aggtcaatat cacggttcat aaattaatgt acgatcaagg aacgcaattg aatgttgata
     3901 ttgacgggat caaaaacgat ggttatacgc acgatcaata tcctacaggt gtaacgaaat
     3961 acaacaaggc agattatggt gatgttgagt ttacgttagg aaatattacg gatcaagtat
     4021 taccgactga agattctgat ctaaccaacg cgaaagtgga cgaaatcgtt aaagatgtag
     4081 aagacaaggg atctaacagt gagtacgtca agaatgcaac caataaaatt acttcagctg
     4141 tagatgaaaa tggtgagatc acttttgctg atcaaccagc ctatgtcaat tccaaaggga
     4201 atgtatatgt ggtttatgaa agtaaatccg ctgctggatt agtcacacaa aaagcaaaac
     4261 caatggttgt gattgcgcca atgactgata atacaggttc aggtttttta aaagacattc
     4321 acttatatcc taaaaatatt gtttctaagt tgagttttga attaacgaaa tttggtgacg
     4381 atggcacagc tcaaagcaaa caaacacctt taaaaggggc aaaatttgag ttatacaagg
     4441 gcgaacctgg aaaaggaaca aaattaggag atcttgtatc ggatgatcaa ggaaagctga
     4501 ctgctactga tttgacgtta ggaaaatact attttgtgga agttccttca gaagttgtag
     4561 tgggatcaga taaagaacca acagcagatc aatatttatt aggcgcagac gctcgcaacg
     4621 atgcgcacaa taaattaacc tttgaaatta cgaatgatgg cgtgacaagt gacttaaaag
     4681 cttcatacgt aaactataaa gcaccagtga tcgataaaac agtaacaaat ggaacaggac
     4741 aagaacattc tttccaaatt ggtgacgcag taaattatca aggaacgatt catatcccaa
     4801 cagacattgc aggcggagca gacggtatca cagtaaacgg agtgaaaagc gaaacttctc
     4861 cttacagtgt atttaaatgg ggggatacag caggacaagg actttcttat gtcgctgcta
     4921 aagcaaatat caaagtaaca aataaagatg gatctgtggt attaaaagaa aatacagatt
     4981 ataaaatcca aaattcagaa aatggctttg tgatcgattt tatcgtgaat aatggccaag
     5041 taagtgatac tgtagcaagt ttacacggac aagatcttca aatgacttat aacatgtatg
     5101 taaatgatag cgcagctgtt gccaatccat taacaaatag cgtggatttc gtttataaca
     5161 acaatccatt taatcaggaa gaacaccacg aaaaaacgaa agctgacgtt gtgacttatg
     5221 gtgcaaaatt cttaaaagtc gatagcggac tatttggaac aggaatcaaa gcaacaccgc
     5281 ttgaaggcgc agaatttgct gctaaaaacg cagaaggaaa atattatggt ggattagttg
     5341 atacggataa agacggtgtc aaagaagcag tatgggtaga cgatgtagca aatgcagcga
     5401 tcctaaaatc agataaagaa ggtcactttg aaatcactcg tttaactgaa ggtgaatatt
     5461 cattggaaga aacaaaagcg cctgaaaact atcaaaaatt aacgaaagag atctctttca
     5521 aagtagacaa agattcatac aaagaagaaa accgaatcac gatcaaaaac aatcaaaaag
     5581 tttccgtacc aatgactggt agcaacggtt ttcaaacgta tgtattaatc tcttgcttgt
     5641 tgctaggagc aggggcactt tctgcagttg tttactttaa gaagaaagcc tagaaggatc
     5701 aaaaccaatg attatcagga agcctaagaa aaagcgaatc atgggtaaat ggatcattgc
     5761 tttctggtta ctttcagctg taggtgtctt acttttgatg cctgctgaag cgagcgtggc
     5821 gaaataccaa caaaatcagc agattgccgc aatcgatcga acaggaacgg cagcagaaac
     5881 ggattcttct ttggatgttg ctaagattga gttaggcgat cctgttggta ttcttacaat
     5941 tccaagtatt tctttaaaac taccaattta tgacggaacg tccgacaaaa ttttagaaaa
     6001 tggtgtaggt attacggaag gaactggtga tattacagga ggaaacggta aaaatccttt
     6061 aatcgcaggt catagtggac tttataaaga taatcttttt gatgatttac cttcagtaaa
     6121 aaagggagaa aagttttata tcaaagttga tggtgagcag cacgcttatc aaatcgatcg
     6181 gattgaggaa gtgcaaaaag acgaactaca aagaaacttt gtcacttact tagaaccaaa
     6241 tcccaatgaa gatcgagtaa cgctaatgac atgtacgcct aaggggatca acacacaccg
     6301 ttttctagtg tatgggaagc gagtaacctt tacaaaatca gaattaaaag atgaagaaaa
     6361 taagaaacaa aaattatcat ggaaatggct tttaggaagt actgtttttc tttcagtcat
     6421 gatcattggt tcgctatttg tttataaaaa gaaaaaataa aggagggtaa ccaacatgag
     6481 aaatagaaaa tggctatttg tttgtgcagc cgctcttttt actttcactg cctacacaca
     6541 gttgacggtt gcagacagtc aagaaagcac ggatagcaca gaacaaacaa tccaaacgtc
     6601 agatagcagc gcgattcaaa gcagcgatga aaccgtcgat tcgtcaacag ttgattcttc
     6661 agaagaacct aaaattgctg aagacgatca aatagtcaaa cagaccattc acgttcaaaa
     6721 aattatttct tccgaacaat tagacaacca ggggcaaaag cttgaaaaac aagaaggagt
     6781 aaatggcgcg aagttttctg tttatgatgt atcggacatt ttacaaaaga tggatgttaa
     6841 ggatctcact actgaccaaa ttgaatccca attaaaagat cgagtgaaaa aactatccag
     6901 tgatcaactg aagctaattt ctaatggaga aacaaagaca attgatcaac aaacaggtgt
     6961 ctttgaattc tcggtagaag tacaggcaaa tcagaaacaa gcttattata ttgtcaatga
     7021 atcaagtcct gaaaacattt ctaatagcga ggatattttg ctattaacac ctgtttctga
     7081 taaaaatggt gaattcttaa aggatgtgtg gatttatcct aaatcagaag cttcgcaacc
     7141 taaagaagaa gtaaaaaaaa tcgtatctac tggcgtaaag aaaaacttct ttgagaattg
     7201 ttgggatttt gttactcact tgttttctag agattaagga agaaataaga tgaaactgat
     7261 caaattatta ttattcaatc tttcttgttt aaccgcagtc tttttgtact gcggtttatt
     7321 attttctcaa ctatctattt tgccaagcta ccaactatac ctaatgagga ttttaaacat
     7381 accagctgct tccatgccgc tagatattat ggaaaagctc attaggaatc cattatttac
     7441 tacgatcaat ttgatcgtta ttgtcggaat ttcactagtc atttataaaa aagaggggat
     7501 gaagggatga attttaaaca ctcgtggaca agacggttaa aatatgtttt tcccataatg
     7561 atgatgttag gtacattgtt tgggttaaaa acagccaatg tctttgctga aaaagttatt
     7621 gtcgatccgt caaatccaat ccagaacgta aagaataatt ttattattcc aaaagatgtt
     7681 cctaatgcaa aaacaaatat tactgtaaac ggagcgtcaa aagtttacaa atatcatgtt
     7741 gatgccaaca aaggtggttt tacagacgac tacgtaggat tagtggaggg aaacaaaaat
     7801 atacgctatc cttctttcca aaaggaatac ggtgaaacaa accttgtttt agaaggcgta
     7861 acaacaaaca ccaaagtcaa tattgactat ggaaaaatcg gtacgtataa cgggaaaaaa
     7921 gtcaatatca agctagtttt atctaatatt cacttatact cggatacgtt gccgtggaat
     7981 ctactagata ataactatac aaaaactcat tttcgagacg atggctataa aaatacgaat
     8041 ggtgcaatga gtaaatctaa aaaaagaaca gtactttgga tctcagacaa tcttttctca
     8101 ggaattgttt accattcaac acaaatgaat gtgcagctag tagccacata tgaggacggt
     8161 agccccgttc aattttcagg agatacattt atcagtttta actctttgaa ccctgcagga
     8221 ggaaaaagca cggatcttaa aggagaatat acccactatg acaaaatgaa tacaacagat
     8281 tggtatgtca gaaaagatac ggttctttca gaatttaaat ctttctacaa caatctgaac
     8341 gtggtaggtg gccacccagg aggaagctct aagctgacac aagcggataa tgatttcaat
     8401 aatttgcatg ataaattagg agatccgaag tttggtcaag gtactgtgtc ctttaaaata
     8461 tctgaagcaa atccgacgtt tgtgattggt tcttctaatg ttcaaacctg gtttacttta
     8521 tcttctgcga caatctttag tgttgttcct gatcaacctg aaaaaacagg ggttgataaa
     8581 aatggaaata acgtgaacga taacatgttg caagtaggag acacgattca atatcgaatc
     8641 aaacagaagg tgaatcgatt gggagtggat ttactagcgg tttacgatcg atttgagtta
     8701 atcgataatt taccaaaaga agtagattac gtcgatgcac acgttgaaag tggtacaaat
     8761 aaaaaattcg atgtatctgg tgaagtgacc tatgacaaaa caaaacacca ggtaaaatat
     8821 gcagcgaaag ctgatacatt aaaaaatcga atgaagtata acggcgaaac ttacgaatta
     8881 gtgatcaatg taaaagtcaa tgaattggcc aatcaaaata gtgtagccaa aaatcaggga
     8941 acgtcgatca ttaataaagt agaaaaggat acaaatatca ttaccgttta tttccctaaa
     9001 attccagtga aagaagtaca acaaaatgga aaagatgtaa acggacgaaa tgacggtaag
     9061 aagggtacgc cgacagctcc tttaaacgca ggatctgaag tacaatatct agtcacacaa
     9121 aaatggcaca caaaaggcgt agacgctgcg tcagatcact acaaacaatt tagtattcaa
     9181 gatccaattg aagctcgttt gacatataaa gaagtttctg cgcaagtaat agataagagt
     9241 aaaggaaaag atattacttc tgaaggcaca ctaacctatg atagcaattt aagaacgctg
     9301 aagtgggaag cttccgctga cttcttaagt aacaatcttt tagatggacg agaaattcag
     9361 ctgatattta cagctaaaac tccattacaa tcagaaaaaa atattgataa ccaagccgta
     9421 gtagcagtag ataatgtttc taataaaaca aatgttgtga caattggggt tgatcctaac
     9481 ttgccacagg tcattgttcc taaaacaggt tctacacatt tagtaacgat ttcagcggtc
     9541 agcttactat tacttgtgtt agcaactttt agttatgcgg ttctgagata catttaaaat
     9601 aaaaaaacga aagaatgaat aaaatgaaaa agttaataat agtagttact tccttgattg
     9661 ccatgattgt tattttagtc ggatgtagta atgaaaaaaa taaacaaact aatcaagata
     9721 atggcgtatt gaaatcagga actatgtgga aagaagaagt aggtggtctt gtttataatt
     9781 tgaaaattat agacgagact acctgggaat actctgagag tgtatggcat ccagatcctg
     9841 tacaaataac agtcaagagg caaaaagact ataaaggttt agaaagatac aaaatagtag
     9901 attcagctgg tgttagggaa tttataaaca aatctgattc tttatttatt gttgttccct
     9961 atgagaagaa tggcgtaaaa aaaataattt ttcttggatc tagcaaggat gaaaagcgaa
    10021 cgaaagagaa attgattcac gatggatcac aatccaataa atataagtta caaaagacta
    10081 gcgagtgatt gctagtcttt ttatttgtcc tgaaggagga atcacagtgg caaaagctaa
    10141 aacgccattt gaaaaagccg cgtctaaaat cttagaacgc cgcggtgtat ctgaaacaca
    10201 gtggaaacaa gaagtccttg aaaaagcaca atttgaccta ttacggggaa aagacaagga
    10261 cttagaagga tatatctatc aacgtgaacg tgaaaagctt gttttcgatg aaattattaa
    10321 acactaaaag gagcgaacaa ttttatgttt gaatcaatta caatgaattt tttaacacaa
    10381 ccgaaagtag tagctgcggt tgatattttt agagcattac aaactgccgc aactagttta
    10441 aaaaacaatc tgatgatttt tgctgctgct gcggccgttg cttccattgt tattgggggt
    10501 cttttcttcc tatttggacg aagaggagct gaaaatggga agatgcacgt aggctatgta
    10561 ttgatggggg taggagttat tttagcagca gcttctattg tggtttcgtt atttggattg
    10621 tttggacaaa cacctcaagg attataagaa agtaaaaaag taggagtaag aagtagtcga
    10681 tactttttac tcctttttta tgaaaggaga atactcatgt actttacgat tgcaggcaat
    10741 accaaaacag ataaagagtt aataaaaaaa gcaacgaagg aagtaggaaa gcgtacttct
    10801 tttttaccga aaacaattaa atattctgtc attgaaacgg aagaacagct acatgtgtta
    10861 gggaaagtac tggaacacga aagtcgatct tctgttaagt tgactctcac gttacatgac
    10921 acagaaggaa aaatagagaa agctggtaca gaatacgttt ttggcccact ggattatcaa
    10981 atttcagaag gtttctatcc tacattgatg gatttaatcc gccttgatgt gtttaaagaa
    11041 acggatgaaa ctatgagtgt ggaagagtct tatcgaaacg aaaaactttt acaagtttta
    11101 gaagaagagt tagagagcga ccaaagaaaa gtgaatcaag ggagtgaagt cgaagtaaat
    11161 gaagaagtac catgggaacg accaatattt ccaaagaagg agtcaaaaga aaaagagaca
    11221 gtctatgttg acgaacaagc tgatattccg actcagaaat cgatatttga ggaagagaac
    11281 gatgtgatgg gtcaattgga ggtagatccc tttgaagaaa caatggagga tgaagagacg
    11341 gccgaagtag aagttgatcc agttgaagct aatgaagagt caacatggac tgaaggggat
    11401 tctcaggaat atattgaacc acttatcagt gaagaagtag aaaaaaacga aatagagata
    11461 caaaaggcaa ctgtatttga ttatattttg gatcaatatc cgccagagca tgaatggatg
    11521 aaagaaaaaa acaaattatt tttaaatgag ctttattcga aatatcaatt accccaaacc
    11581 tatcaagcat ttttagagag taaagaagaa ttaatctcac agggtaaagg cacactttta
    11641 gaacagttag agtctgtcca atcaacaaat tggcatgagc ttgcacaaga agatttatta
    11701 gccacctttg aagaacgtca acaagaaaca gatcaagaaa ttaatgagta tgcgacggaa
    11761 cagtcgtcta attgggagaa agcaaaagag gaactaaata aagaagaaca gcgagtgatt
    11821 gaagaagaag tacaaaaaat taaagagcga tacgaaaaga aacgcgacaa tgcgtattcc
    11881 ttgtgtgtag caaagatcaa taattttact cagacgaatc aagaagcgtt atcgaaagaa
    11941 aaagaaaact tgttaaaaga acgtattaaa gaacgaaaag aagaatttta ccgaggtttg
    12001 cgtacagata agctaaagat tagcaaagaa ttaaatgaac aactgaataa gctatatcaa
    12061 acaacgactg aagttcttat ggaaaaacac gaacagatcc agcaagaatt acaagtacaa
    12121 attccaaaat ggaaaaaaga gtatgaaatt caacaacaag aattgaaaga acaagaagaa
    12181 aaacaacggc aaaaagaaaa agagcgcgaa caattagaac taaaaaaacg tgaacaggat
    12241 cttgcggaac aacaaatggc aatagaaaaa caacggttaa accaagaaaa ggaaaaagaa
    12301 gctgctcgta aggaacgtca agaacaaatg gatacattgc gacaagctca gttaaattat
    12361 ctagcacaac ctcaaccaac gccttcagta gctgctgttc aaaccccaat gaacaaccaa
    12421 acaaatctaa ctccttcacc acagcgttcc tttaacggat ggatggtggg atgtattgca
    12481 agtttaagct tgcttctagg tggagggaca gtatttgctt ttaatcatat caatcaattt
    12541 tcacaggctg attctgtagc cacaacggcg tcaatcaagg aagaagcccg agaacaagca
    12601 agaaaagagt atgaacaaca attggaagaa ttattgaatc gtaccaatca gtcaacaaca
    12661 gagtcaagta tggaaaatag caaagagagt gatcctagta aggctaaaga aggatcaagc
    12721 gattcaactg tacaatcaaa cacttccgaa agttcagaat caaatgaggt gaaataatgc
    12781 gtgttagaga aacaacgaga cgaaaagaca aacgattcaa tttagaaaag aataggtatc
    12841 tttctcattt ctatcgctat actccttcag gagaagagct accagaaaaa catgacaaac
    12901 gtatttctca aaagattttt tatagtggat tagcttatct tcccttaaac tatgttgtta
    12961 caagaatacc agaagcattt catcgatttg agattattcc aggaagttta caaggagtga
    13021 aaatttttca gttacaagaa atgccgcagt tattccattt tgattcaact ggtttttgga
    13081 atcctttgac cccaacaaca agtttaggca cacgtttagt tgtttctacg atttgtgttg
    13141 ttccagctat acttatggga ttgaaaatgg acatgtggtt tcgtcctcta gcagatgggc
    13201 aaaaaggaga taaccgatta aaaacgttaa aggaaatcca acaaatttat ccgcaaatac
    13261 cagaatcaaa gggaggtttt cctggttatg gcggaatacc aattactcat tataaaaagt
    13321 actggtatat tcagacggat acagtaaata cttgtattat tggtacttcc cgttcaggga
    13381 aaggacagat agaagtttta gcaaccattg acaatttgtc tcgtgcagaa agacaaagtt
    13441 caatggttgt taatgatcca aaaacagaat tatatgttgc tagtaaagat gaactagaag
    13501 ctagagggta tgatgtgtat gcatttaata tcaccgatcc actgcaatca atgagtgata
    13561 atccattggc actcatcgtg aaatactgga agcgaggaga catagatact gcaacgcagt
    13621 taaccaatac ttttacgaat acgatttatt atgatgccaa tgcttcagac aacaaatact
    13681 ttaacgaaaa tgcgcagaaa gctgtaaatg cgcttatttt tgcgttgtta gaacaagccg
    13741 atcaaacagg ggattactcc aaattaacac ccaataatct tgttgagctt ctttctgaaa
    13801 ttggcggttt taattatcaa gatcctgaga atgattacaa acaactcaat gccttagatg
    13861 aattcatgaa tcagttacca cctggaaaca tagcaaaaaa acaatatggg gcaacaaaaa
    13921 ttggttctga taaagcaaaa gggaatattt tatcgacggc aatcacagga ttgaatccat
    13981 ttaccctaac gaaaattgcg aaaatgactt ctcaatcaac cattgattat aagtccattg
    14041 gttttccgaa gtatttggat ctcaaactac acgagagtct gttaaatcag cgaattgttg
    14101 tagagtttta tcatcaaggg aaaaaatttc atgaggaacg tgtcaaagta ggttatagag
    14161 gtttttgtga aatcaacttt gattgtcatt tagagcaggg agatcatgtt tgcttaaaat
    14221 acgatcatca aggaaaagaa tatgttgctt ggtatgagtt ttctcaaaga gtattgaaag
    14281 acgaagaggg aaatatcgtt tatcgaaaaa aacgagaaga aacccattta ccagaattag
    14341 aaaaagaagc tgttctaaca ttagatgagg ataaaagtaa cttattagta gagtctattc
    14401 ggatgcacta taccgataaa ccaatggcta tttttatgct cacacctgat tatgatccat
    14461 ctaaccatat cattgttagt atttttctta gtcagttgta taaagaatta tctacgcaat
    14521 gtgttaagac taaaggagat aaatgtcacc gtaggattca ttttatttta gatgaatttg
    14581 ggaatatgcc accaatggat aatatggaag gaatcatgac agtcacagct ggtagaaaca
    14641 tgttgtggga tctgtttatt caatcctatc agcaacttta tgcgaagtat ggggaacaaa
    14701 acgcagcgat tatcaaagaa aattgtcaga cacatattta tattatgtcg acagacgata
    14761 ataccatcga agaattttcc aaaaaagtgg ggaataagac ggttgaacaa gagaacagta
    14821 ccaccaattt attaggtatg aatactcata tcaatcgcaa tgttgattca gatcgtatct
    14881 taactcctga aagaatttct acttttttag aaggtgaaac gattgtactc gctcctttaa
    14941 aacgacaaga tttgaaagga cataaaatac ggccgtatcc tatttttaat catggggaaa
    15001 cgaatcttcc ttatgcttat caatatattg aagatttcaa tccatcgtgg gatatcaatg
    15061 atatagacat acattgtaca catgcggact tggatcttaa ggctttacaa attgattatg
    15121 attatttcct accagatgaa tatgctagaa atctctatca tggactgcat gatcaattag
    15181 aagaaaaaaa cgaagaaaat atgttttata aaatcgttca atctcttgaa aatgagacag
    15241 cccaaaaatt attaattcaa ttttacgaag aacaagcaac ggatcgtctt caagaatatg
    15301 ttgaaaagtt gatcaaaaat gaagaaattt ctgaaatgat tgggaaacgg ttgttattgg
    15361 aagctgaaaa ggcggtgaaa gaatgatcat tggaggaatt ttttctggca tagccgactg
    15421 gtggtcaggc ttattcggag aaggggatgc aaaccccaaa accgtaacga aagtcttaca
    15481 agattatggt aattatctgc agtatcaaga tgtatttagt tggatttgga acacttttct
    15541 gtggggattg attaaaggat tatataatct caatacttta ctagaaaaaa ccatttatca
    15601 aagctttgat ttaaaagact tattgaacgc cgctggggta aatgcactat ttcaaagttt
    15661 gattagtaag gtattggctc ttttttgtgt cgtcacatta atttatttag gcttgaaatt
    15721 ttttatgagt aaacacccac caaaagtcaa aaatatcttg gttaatttat ttatggccat
    15781 gatcttgatt tttggtggga gttctttaat cgatgaaggg ttaaatatca gtaaaagctt
    15841 ttacggagac gtcactgcag caaataaagc agataaaacg ggttcacctg cttttcaaat
    15901 tattcaaaat aatgtgatcg atgtcagtac attactagca actgacccga ataaagtaga
    15961 atccctgcca acagacaaaa gaaatgcttt aacagcgaaa aattttaaaa cagcgaatat
    16021 caatgggatt attactccta aacaagctaa agaaatggcg gataaagata agagtggttt
    16081 atcagattta caaaaggatc ggttaagagc gttacaatac cgattggaac tagatgataa
    16141 tgggaaagaa attcctgttc aaattagtga cgaaggctta gcaaaatatg tctatacttc
    16201 agggtatcgt cgatacagta gtaaaccagg tattatctta gctggtgaat cttctttggc
    16261 ggtggcctat ttatttatcc tatttacgat cgttacttgc attattgagc tggtatttaa
    16321 aaaattctat ttagtgattg ccgcgtcaac ggactttgag acaggccaac ggatgaaaag
    16381 tgcgatagaa gatatttctc aatccttctt gttattggcg tttacgattt tagaattacg
    16441 aatctataca ttaatgcttt caggtatcgg tgatttgcat gcggcaggaa agatcaatgg
    16501 attcttgtat gttgttgctt taattgtgct aactattgcg ctattcaaag gctctcaatc
    16561 ggttacgaag attttcggtg ttgatacgag tctgaaaaac ggcagtaatt ctcttcttag
    16621 catgtttgcc ttaggaaata ttgcgaaaaa tgtgggtagc ggagctaaaa accttgcaag
    16681 tgctggtaag agtggtttaa gccatttaaa tgatattcgt aaaaatggat ttggccatcg
    16741 aaaagatgtt acccctgata acggggaaga acaatcagac gataaagcta caactgtacc
    16801 taatagtaag aaaacagttt ccgaaatgtt cgggaaagcg aaaaatggtg tttctaaagc
    16861 cgcagaaggt cttggttacg tcaatgaacg tgggttaaaa ggaacagctg aagatcttac
    16921 agaaaaagcc aaagacacct tagaagagaa attagacggc acgagagcta aagaattggc
    16981 tgaagctgtg aagaatccat ccgaagcact agaaaaacaa aaagaaaaag cttcagaagt
    17041 caaagaagga ctaaaagatg cgtatggtga aggacaagtt aatgcagcag taaaagctaa
    17101 tacaacaacc gaaaaagaaa atcaagaagg tatagtgatt ccttcagtca aagatcacca
    17161 agaagcgttg cactctaatg aaaattcgat tgaagagaaa aattccatag aagaaagaaa
    17221 ttcagaagaa ggaaaaaatg gacagttacc aaaaactgat ccagaacaat atcgctataa
    17281 acctaacagt gaccttgaaa atgagaagcg aatttcagat ttatcaaaag taaatcaaga
    17341 agacaaagca gaaaatgagg gacagttacc aaaaactgat ccagaacaat atcggtatag
    17401 atctgttaac tccgaaaatg aaaaacgcat ttcagattta ccaaaacgaa atcaagaagt
    17461 acaaacggat gaggattcca tcgttctgcc aaatgataat ggaatcgaag ttggaactga
    17521 aaaatcaacg aaaattggtt tacctaaggc acaaaattta ccaatgaaag atagtcgttt
    17581 gaatcaattc aaggagaatg atcaaagctt tgttcaccaa tcaactgcag gtactgttca
    17641 aatgaaacca agtcgtttgc ctgaaaatgg aaatctgaca actgtttctt acaatttatc
    17701 tgaaagtggt gagacaggga atgcgtccgt tcaaaatgtt gtgacaagag aagctgcacc
    17761 aaaacctatt caaaacgttc atacaggtta caagccagca aatgtggcat ttactgcacc
    17821 aacaaaaata aatgtgacaa gagaaactaa aaacaggaac aatgcattga aagaacaact
    17881 attgagggat atcaaacagg atatcaaacc ataaaaggcc tacaagttag gccttttatt
    17941 tatatgaaaa ggagaaatca attatggata aatatataaa catgaaaaac cctccaagat
    18001 ttagtggaga atggaagttt ttcgcttttt tctttttaga tctattaacg cttggtggct
    18061 gctttttttg ggcgaaaatg gtcaataatc ttgtccactt accactcttt tttgcactct
    18121 tgaattatgg cttatggatt gcgatagcgt tagtgattgt ttggcgaccc tataataacc
    18181 caggtcaacg acaaattttt gcgattatcg agtctatttt ttttgcggac aagaaccatt
    18241 atcatgcgtt agatcctaac cgaaattatc atggtacgta taaggaggat gaataaatgc
    18301 gagtcaaagg acaaaattca gttgaaagga aatccatttt gcagtttgga aaaccagaag
    18361 agcgctctat cttggactta tttccgtata aatcctgtac agaagaggga gtcttaatta
    18421 ctagagaaga tcattttcaa cgttattatc gtgtagtttc tacagacgtg gaaggattaa
    18481 atgaacaaga gaaactagaa cgaatgaatc agttgaccac cgtcatgcgt acgtatgtgc
    18541 caacaattaa gttagttagt ttgaccacag agacggatct aacggaacaa atcgtgcaaa
    18601 agcggcaatt attagataaa aatcgtatgg aacagtcctt aggaagaaat ctacaacgat
    18661 taaaaaaata tgaaaagaaa ttagtcgaag aaatccagga attgaaacga gcagaacaag
    18721 aacgtcctga cttaagcttc tttttcgtca ttgaaggaaa gacaatcaag gatttacaaa
    18781 ccagaaaccg tcagttaatg cgatctagtg gcattttagg gttaaaacca ctctacaaaa
    18841 aagaattgat caagattctg tatcgaatga acaatatgaa tgatgagtag gaatggagaa
    18901 gagagaatga aatatccgtt gatatggtta gaaaaagatg ttccgaagga agagaccact
    18961 agaaaatttc ctcacacttt aagcctgggt aagttgggaa aagggcaatc ttttaaccaa
    19021 gtaaagaatc aaacaagaag aggtgactgt acatgttaga agcaattaaa acagcttttt
    19081 caccacaaaa tgatcaaaaa gtacttgatc cattaaagca actaggaaat cgggaaatag
    19141 aaattttaaa atccaaaggg tatgatttag attttttaaa acaagtgatg ccacaaggtg
    19201 ggttaaattt tgatgaagaa tatgtgacgt atggtaatgg ttattcacga tgtgtgacag
    19261 tttatcacta cacaaaaaat cctacgcttt tttggttggc caatctcatg aacaatcctc
    19321 atacagtggc cacactcgat gttagcacag atgaaaagca aaaagtgatt gatcaaatca
    19381 atcgtgcctt agatgaatta aatgatcgat cagataatga acgaaaagcg actgaccgaa
    19441 ataaaagcgc agaagaatac ctggaactag cggaatatgc tcgtaaattg acttctaatg
    19501 gggaaatttc taagcaagtc aaagtgagag tacatgttta cggaaacacg attcaagaag
    19561 tagatgaacg agcgcaggaa ctgatcgaaa atctaaaagg gatggattat cgtgcggtga
    19621 cttatctgca taaaaccaaa cgagattggc aatcgatgtt taccatgttc gatgaacaag
    19681 ctgaatggtt cggaaatatc aaagggcaat cactaccatc gttaaacatt ggcggaggtt
    19741 tcccgttcca ccaccaaacg ctaaaagatc caggagggac acaatatggg gaaaccatga
    19801 caggcggccc atttgtctgg aatgcgacgt ataaaaatag tgtacggttg tctactaata
    19861 ccttgcttct aggaatgatg ggagctggta aatcgaccgt tcttaaaatg atcgcggaag
    19921 cccatttagc tgcaggagac tttatttggg gctttgaaaa gggaaaagac tttattcctt
    19981 tcttaaagga atataacggt attatggtgc gtttagacgg atctgacgga atgatcaatc
    20041 ctttagagat atttgccaca cggacgtatg atgaagcatc cagtttatat gacgatggat
    20101 cagtcaaaga tttgaagatc aatgaagcag cgtcctatca aacacactta gacaaagtgg
    20161 tctatcaggt acagttagtg agtcctcagc taaaaggaac gatgaaagca gaatttaaga
    20221 cctacttaaa tcgtttttat gaagagtatg gaacagtacc acgcggcttt acttcctcaa
    20281 attcgcgttc aaatacggag acgcaagtca caggtaaaga tccagaagct tatccgacgt
    20341 tcaaagaatt tttagacttt ttaggacaac tggaattacc aggtgcttcc caagagaaaa
    20401 agaatcgaaa agaagaaatg gaatccatcg tagaatcctt atgtgagacg tatggcatga
    20461 tttttgatgg gcatagtacg attcgacacc ttgaccaaca acagttggtc ttttttgaca
    20521 ttgactctat tacaggctta gatcgagggg tacaacaatg tcaaatgtac atggctatga
    20581 cgttgatttg gaatcaggca ttgattcaag gaagaagaca acgacgttta attaaagaaa
    20641 aacaaatgga agaacaagac ttcaaacgct tcttggcgat gattgatgag tgccataatg
    20701 cgattaatcc agattttatt gaaacggtaa attatgtcac aaactttcaa cgagaaatgc
    20761 gtaaagtaga agcaatgact gttttagcta cacaatcccc acaagaaatg gtgccagaaa
    20821 atatgtcttc tgataacttc tcgaaactga agaaagtctt tgaattttct tctacgaaga
    20881 tctttatgcg tatggatgaa tctattttac gtcatataga aggattagtg ggtaaatcaa
    20941 tgacgaactc agaattagaa tccattcctc aacaaaatca aggagacgct gtgatcaatt
    21001 ttggctcaaa agaaaccatt cgtgttcatt ttagtccgaa caaacgtcaa ttaaaattgt
    21061 ttgatggagg aaaataatgg aaaaccaaaa tgaa
//
LOCUS       DAZKKZ010000052        20506 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.053, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000052 DAZKKZ010000000
VERSION     DAZKKZ010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20506)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20506)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20506
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.053"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(19..492)
                     /locus_tag="ACG8LA_002048"
     CDS             complement(19..492)
                     /locus_tag="ACG8LA_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fur family transcriptional regulator"
                     /protein_id="HFQ0204340.1"
                     /translation="MVMNAISAMKKTKQQLHEAGFKLTPQREATLLVLLENEKEHLSA
                     EEIFFLVKKKSPEIGLATVYRTLEILTELKIVDKVSFNDGLARYDLRKEGAKHFHHHL
                     LCLNCGTIEEVEEDLLLEVEQVVEERYHFLVKDHRLTFHGICQECYEKEKRNQSV"
     gene            complement(597..1460)
                     /locus_tag="ACG8LA_002049"
     CDS             complement(597..1460)
                     /locus_tag="ACG8LA_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virulence factor B family protein"
                     /protein_id="HFQ0204341.1"
                     /translation="MNDLLATIFTGIIIDENEKNYFVQKNGQTFGLSKSEGEHKIGEA
                     VEGFGYQNQKHENRITTQIPKSRIGHYAFGIVTATRKDLGAFVDIGLPDKDFVVSLDE
                     LPTMTELWPKKGDRLMISLRVDAKDRIWGSLADEKIFKSLSKYGTEEMKNKDVIGTAY
                     RLKLTGTYVLTEDFYLGFIHPSERYNEPRLGEQIKGRVIGVRPDGVLNLSLKPRAYEA
                     ISDDAQMILTILERSADQQINFTDKSDPEEIMKAFGISKGAFKRALGNLLKQGLITQE
                     NGVTKLVKKSN"
     gene            complement(1656..3755)
                     /locus_tag="ACG8LA_002050"
     CDS             complement(1656..3755)
                     /locus_tag="ACG8LA_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division site-positioning protein MapZ
                     family protein"
                     /protein_id="HFQ0204342.1"
                     /translation="MKKCPNCGSKKMEQNTICPDCGHQITAEDQQIKESIEETNTDAA
                     MQDKSTEDAVFPDTELNDPIEWSELKDLPLESVMELFEKAEPEDEEPPAHDQVTNIEK
                     NEQKKATVHETSEESGKNQEETLESKQKRRVAELKEIVDNEEENSILSAYIKAHREDT
                     KEEHAKELLKMISEKIAQENKVEPEKEQETEKDSDRENATGKETVKIKDVKTDITEKT
                     EVFTEKQLEKEKTNKLPEAEKKEILENTDKKSTEPDEINSESDAENQSVSKEGTDLEA
                     KIEKEENQPKLFEAEAKSITIVPDTEKTHQESNLEKTDPDKAQKKKSKKVPYLVLAAV
                     LLLGGGSWAYYDHHQKVEAEVAAEAKRQQQMEELHEKLAAFYTDDHHQFIRADMIHQD
                     LSKLKNDLSSLKNEKGYSELETTYQDIQSKIRDIQKVNEWFIAPAIVDDHLADDIKLK
                     ADKEIQAIETDNTDFGKLIQQAQTEAKNQYAELQTAKEKTAIVFKDGKVVDSATRDQY
                     KTAKEAVEKVKNTDLSAQLNEQLKQVDKMLTDKEKKEEEEKKKAEEAKKAAEEQAKQA
                     AQAAAAAQAAQQAAVAQAAQQEAASSTPSSSNSANQPIKSARASDIADASNPAWTWAP
                     GVQSKVIATCIQRGYIVEGGYRLEKARIENGEGYYNLYATSTKSALMKGIGESALPFY
                     IVTINCKTGWFGGNGSN"
     gene            complement(3975..5084)
                     /gene="rpoD"
                     /locus_tag="ACG8LA_002051"
     CDS             complement(3975..5084)
                     /gene="rpoD"
                     /locus_tag="ACG8LA_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HFQ0204343.1"
                     /translation="MANGTDKKTYEAAVAAFIKENKPKRQVVYDDLSNQLATPFTLNA
                     DEMDKLIQKIEDAGISVVDENGDPSIHSLKSAEKKAEQAKTEDLSAPTGVKINDPVRM
                     YLKEIGRVSLLTAEEEVALALKIEEGDQEAKQRLAEANLRLVVSIAKRYVGRGMQFLD
                     LIQEGNMGLMKAVEKFDYRKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETIN
                     KLIRIQRQLLQDLGREPTPEEIGAEMDLPTEKVREILKIAQEPVSLETPIGEEDDSHL
                     GDFIEDQEATSPAEHAAYELLKEQLEDVLDTLTDREENVLRLRFGLDDGRTRTLEEVG
                     KVFGVTRERIRQIEAKALRKLRHPSRSKQLKDFLE"
     gene            complement(5108..6949)
                     /gene="dnaG"
                     /locus_tag="ACG8LA_002052"
     CDS             complement(5108..6949)
                     /gene="dnaG"
                     /locus_tag="ACG8LA_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003896 - DNA primase activity [Evidence
                     IEA];
                     GO_process: GO:0006269 - DNA replication, synthesis of
                     primer [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HFQ0204344.1"
                     /translation="MAQRIPQEVIETVRSQTNIVEVIGQYVQLKKSGKNYLGLCPFHE
                     ERTPSFSVAEDKQIFHCFGCGKGGNVFTFLQELEGLSFPEAVVKVADFEQIPLEDQWR
                     QRTIAVQNPESATGKLIAAHEKAAEIYHHMLLHTKAGQPALEYLQSRGLSLELIEEFN
                     IGFAPNERSFLQQVFKNESISNELLERSGLFVTHDDGRMSDRFYQRVMFPLRNSQGQT
                     IGFSGRWLAPEKGQEKDQPKYLNSPETELFNKRQVLFNLDKARSDIRKNGEILLFEGF
                     MDVIAAWQAGIKTGLASMGTSLTAQQIQQMEKLTKELVFCYDGDNAGFEATNRGIELL
                     RQNSRLALSVVVVPEKLDPDEYLRKYGEASFQELVAHGRETVFTFKSRYLKQGKNLDN
                     EKDKIEYLEELLVELSRVVSPIEQDMYLSQLSTEFQIGRETIQKQLRDLRRTNQQNRQ
                     EPQESQHTQVTRQETARKKRPLTQVEKAEQILLYRAFKEVSVRNILKEREFQFIHDAY
                     AEVYFLFDAYVSQHYEFNLAEFLDFLQDENLRRLVVEIEYLPVAEESSPREIQDLLDV
                     ISKSGLADEITLKKQMQQEARRTGNKQLELELTIEIINLTKQLKQAK"
     gene            complement(7131..9446)
                     /locus_tag="ACG8LA_002053"
     CDS             complement(7131..9446)
                     /locus_tag="ACG8LA_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HFQ0204345.1"
                     /translation="MNGLTQQEVVQKMASGQQNDYQEDASKSTKQIFSDNILTLFNFL
                     NFGIGICLLFVGAYSNMAYLAIIVVNIVIGIYQEIHARNLVRKLSIVSQSEVLVIRDG
                     KEQSISTKELVLGDLVKIGAGEQIPADLQVISGRAEANEALLTGESDLIVKETGAELL
                     SGSFLTSGSVMAEVIRVGADNYAVRLTSEAKTHKAIRSELVDSIRKVSKFTSFVIIPL
                     GIILFLEALFIRDASIKISVIASAAALLGMLPKGLVLLISIALTTGVTKLAKKRILVQ
                     DMYSIETLAHVDTLCLDKTGTITEGKMSIQRVEALHPLYEKAIPEIMGTYLAESSDNN
                     ITMRAMRDYFELSNRYDVTNKVAFSSDRKWGAMEFPELGVVYVGAPERLVEEDRLPDS
                     LKTAQANGYRVLMLGIAPNQQLNEEKPAFVEPVALFEIDDPIRKNAQETLAYLHEEGV
                     DLKVISGDNPFTVSNIARRAGLPNYDAYVDLSQITEEMEVREAAHRYTVFGRVSPQQK
                     KLLVNELKESGRTVAMTGDGVNDVLALREADCSIAMAEGDGATRQIANLVLLDSDFTT
                     LPEVLFEGRRVVNNVTKVSGIFFIKTIYSFILSIICAVTAIGFPFIPIQITLIDLAIE
                     GYPSFFLSFEQDKRKITYRYLPTALINALPNALLVVVNIIAVYLLGKTFAWGNAETTT
                     LMYYLLIGISCMAVVKACYPFNPLRIFLAVTTIVGIYVAAMLFHGILEVNLGLGESVG
                     YFFVFMLVNIVLRVLYWKADIQNQLLKRVAN"
     gene            complement(9631..10491)
                     /locus_tag="ACG8LA_002054"
     CDS             complement(9631..10491)
                     /locus_tag="ACG8LA_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HFQ0204346.1"
                     /translation="MEKRQKMENQEVGYTTKDWMLRFVKGMFIGSGFILPGVSGGALA
                     AVFGMYERLISFLAHLTKNFKENVLFFLPVGLGGVTGIFLLSFLVSFLLGAYETTILW
                     FFVGCIAGTVPALWKEAGKKGRDTSDVIIMVVTFVLAYLFLLYGAQLFDGQVDQNFGT
                     WLIAGGLIGLGMIVPGLSPSNFLVYMGLYKAMADGFKEVRLEVIVPIGIGGILCVLGL
                     SKIMDYIFSKAYSKLFHFILGVVFASTIMIIPTDYAGLGVAGVLACPVLFIAGTALGW
                     WMSRLEEQYK"
     gene            complement(10550..11182)
                     /locus_tag="ACG8LA_002055"
                     /pseudo
     CDS             complement(10550..11182)
                     /locus_tag="ACG8LA_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289460.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme family protein"
     gene            11349..12110
                     /locus_tag="ACG8LA_002056"
     CDS             11349..12110
                     /locus_tag="ACG8LA_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFQ0204347.1"
                     /translation="MTDIIVILYTVGDYVKKEKKYAKMPDGSEIYYEKSGQGFPLFLL
                     HGNDGSGRFFSEQVPVLERYYTVYLVDSRGHGRSTNEASMLNFQLMAEDLNTIMLLEK
                     IDQADFLGFSDGANLALVFASSFPKKVHRLILNSGNTLVKGVRFSARVISNIHYAWVW
                     LLSLFRPSLRKNLLVIKLLLHDIGLTENDLKKINSPTLIIVGKKDVIKLKHSLYIAKT
                     IPKASFVLVKEQGHELARKDPERFNREVLQFLSET"
     gene            12136..14727
                     /gene="mprF"
                     /locus_tag="ACG8LA_002057"
     CDS             12136..14727
                     /gene="mprF"
                     /locus_tag="ACG8LA_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HFQ0204348.1"
                     /translation="MLKNTIQWLKNHLGLFKTIFLISVIVIIVGELMSIGKTLSIQQL
                     GETFATIPVWKSGLMLLIGLISVLPMVGYDIILNRMLEQKQNPRYLFETSWLINTINN
                     IAGFGGFVSVGLRSELYGQKKESRNVIQALSKVFLFLMAGLSIYSLLSFLLVVFTPVA
                     PFLKQYWIWLIGGGLYFPVVFLFTTFKKKGFLGGTSLKTQGQLLLVSLLEWTGVLFSF
                     LSVGYLMEIRIDLWQTIPLFIAASVIGIVSMIPGEIGSFDVMMIIGLSAIGVPREIVV
                     VWILLYRLFYYIIPFLIGIVFFFKNIGSTFDQRYSGIPKQLATEIAHKIVVVLLYFSG
                     IMLVLSATIPQAFTEFRWLHSLNPLKFHFIIQFPSILLGFLLIIMGRGIAARVKRAYL
                     PTIFLIVLALLYVLLSDFSFTPVVFLSILLLIILASKNELFREQLIYSWEWRTIDGII
                     IGALSLLYIVIGVYNLPDFPHRRHHFISFFLFPSEKIWFSGLLAIIAVSFMIVLFVHF
                     LQGEKKQIGEAFNEEKALKILTTYGGNSDSQLIFLKDKRMFAYEKDGEPTVLLQFACF
                     NNKCIVMGDPSGKKEDFPEAIEAFIEETDRLCYLPVFYETSEEIVMILHEFGYDFIKM
                     GEEAYVDLNSFTTSGKKMKGTRAVLNRIEREGFTFDVLQPPFSTEQMSTFKNISDNWL
                     GSRKEKGFSLGFFSEDYLQRAPIAVVKNTQEEIVAFATIMPTYTNNKVGTIDLMRYDS
                     KKAPSGSMDFLFLHLFAYMKEEHIQWFNLGMAPLSNVGTSRKSFLQERIAYLVYEFGS
                     HFYSFHGLREYKSKYATNWVSRYTLYSRDSWIAYVMIALLIIDNAPVEQTQGRISGLK
                     KWIRRKY"
     gene            complement(14915..16102)
                     /gene="tuf"
                     /locus_tag="ACG8LA_002058"
     CDS             complement(14915..16102)
                     /gene="tuf"
                     /locus_tag="ACG8LA_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HFQ0204349.1"
                     /translation="MAKEHYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLGKKGLANP
                     QDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQMDGA
                     ILVVSATDGPMPQTREHILLSRQVGVKYLIVFLNKVDLVDDEELIDLVEMEVRELLSE
                     YGFPGDDTPVIKGSALKALQGDPDAEAAIMELMDTVDEYIPTPERDTDKPLLLPVEDV
                     FSITGRGTVASGRIDRGAVRVGDEVEIVGIKPETQKAVVTGVEMFRKTLDYGEAGDNV
                     GVLLRGIQRDDIERGQVLAKPGSITPHTKFKAEVYVLTKEEGGRHTPFFNNYRPQFYF
                     RTTDVTGTITLPEDTEMVMPGDNVTIDVDLIHPIAVENGTTFSIREGGRTVGSGIVTE
                     IEA"
     gene            16470..16826
                     /locus_tag="ACG8LA_002059"
     CDS             16470..16826
                     /locus_tag="ACG8LA_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HFQ0204350.1"
                     /translation="MKKLIGVLVVLGIFLGGSFAAYHYFYGGEAYYTKITTNGEMSAT
                     QADNGEKFTTYTYKQAAYNKDGEKKQVTLREEREHPLKMNAYLKLKVNPRKGVLSWEE
                     IKASEVPKNAAEKIDN"
     gene            complement(17067..18071)
                     /locus_tag="ACG8LA_002060"
     CDS             complement(17067..18071)
                     /locus_tag="ACG8LA_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HFQ0204351.1"
                     /translation="MDIYLKKAILHIIDRETGSPVFSQKELDLTKEYIRDFLQKKIQK
                     ISSAQTKTGQLAEESMIVESLKIAQENFVEASEAIVQRWFDIYQESEEAPSADVFVVL
                     YELDTVMYLSLLKVNYREAYTHFVEADEAGIDNRLILNRAILGAKTQKADEAFAVNLT
                     DWTYELIEKKYEFSGKKELYFSGRVIESVPAPSLEENVKVIQKVAKHLGKKFETEEFD
                     IMADLKEAVYDTIEEKGRLDHEMIAEKVFKENITAKMAFKEEVQEQGFVPEAPPVKEV
                     QEISEKKFGKQKFKLSNGIELIVPVDVYRNPDLIEFVNNPDGTISVMIKNVDEVLNRL
                     "
     gene            18237..19088
                     /locus_tag="ACG8LA_002061"
     CDS             18237..19088
                     /locus_tag="ACG8LA_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HFQ0204352.1"
                     /translation="MNSLTSTYRLSNGYEIPVVGFGTWQTPDGDVAVSSVKEALAAGY
                     RHIDTAQGYKNEESVGQAIKESGIPREEIFLTTKLWNANHSYELVMSSFEESLKKLQT
                     DYLDLFLIHWPNPVAFRDNWEQANADTWRAFEELYEAGKIKAIGVSNFLPHHLDTLAK
                     TAKIMPMVNQVFLAPGELQTTVVEYAKKHDMILEAYSPLGTGKIFDVPEMKQIAEAHD
                     KTIAQVALRWSLQHEFLPLPKSVTPSRIKENTELFDFELTEEEMKQIDQLDGVVGKAK
                     DPDTTQF"
     gene            19105..19350
                     /locus_tag="ACG8LA_002062"
     CDS             19105..19350
                     /locus_tag="ACG8LA_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204353.1"
                     /translation="MDPIERLNSLSEEVTQTFHSDFVFLIDAEKIQHFPARNWTHDQI
                     IEELKKRFDHSLMVKPWHEHEVIYSPELPVFALIPKK"
     gene            19537..20241
                     /locus_tag="ACG8LA_002063"
     CDS             19537..20241
                     /locus_tag="ACG8LA_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204354.1"
                     /translation="MKKKQKQKLLNQFRPSLDGVRGQLFRSLEEESLRRYGLPLQVML
                     DPKNRQILTIGLAGKTNEDTRINVPIDDNFNTVLKRIRSGENGIFERFRDNLLIEIVS
                     YWNDQRLKNDEPTAQAVATPVTEETVSVPEEKTEKPKADTTENTRSTDTNAALSFADF
                     SKAVAEYPKFYTEQNEHEVVINEKNADEPRKLATISMTTENEFVIEKALERKYKVKLT
                     LIPLIEQFAATAITDR"
BASE COUNT         5809 a         4204 c         3585 g         6908 t
ORIGIN      
        1 aaaaagccgt ctagacactc agacggactg gtttcttttt tctttttcat agcattcctg
       61 acagattcca tggaacgtta gccgatgatc ttttactaaa aaatgataac gttcttctac
      121 tacttgctcc acttcaagta aaagatcctc ttctacttcc tcgatcgtgc cgcagttcaa
      181 gcatagtaaa tgatgatgga aatgtttggc gccttctttt ctcaaatcat aacgggctaa
      241 tccatcatta aaacttactt tatcgacaat tttcaattct gtcaagattt caagggttcg
      301 ataaacagta gcaagtccaa tttccggact cttttttttc actaaaaaga agatttcttc
      361 tgcagataaa tgctctttct cattttccaa aagcacaagc agagtagctt ctctttgcgg
      421 tgtcagctta aaccccgctt catgtagctg ctgttttgtt tttttcatcg ccgaaatagc
      481 attcatgacc atttactcaa ccccaacaat ttataataat tacaaataaa aaaagatata
      541 acactatgtt aattaaaatt attataagct agttaagaaa aacatgcaag ggattctcaa
      601 ttagattttt tgactagttt tgtcacaccg ttttcttgtg taatcaatcc ttgtttcaaa
      661 agattaccta atgcgcgctt aaatgctcct ttgctgatac caaaagcttt catgatttct
      721 tctggatccg atttatctgt aaagttgatt tgctgatctg cagaacgttc taaaatggtt
      781 aaaatcattt gtgcatcatc tgatatagct tcatatgctc ttggcttcaa tgaaagattc
      841 agtacaccgt ctggtcggac accaatcact cgacctttta tctgctcgcc tagacgaggt
      901 tcattatatc gttcagaagg atggataaac ccaagataga aatcttccgt taaaacgtac
      961 gtacctgtta atttcaagcg gtatgctgtt cctatcacat ctttgttttt catttcttct
     1021 gttccatatt tgcttaaaga tttgaatatt ttttcatctg ctaaactgcc ccaaatacgg
     1081 tcttttgcat caactctaag ggaaatcatc aagcgatccc cttttttagg ccatagctct
     1141 gtcattgtcg gcaattcatc aagagatacg acaaagtctt tatctggaag accgatatcg
     1201 acaaacgcac ctaaatcttt tcgtgtagca gtaacgattc caaaagcgta atgaccgata
     1261 cggcttttag gaatttgtgt agtgatccga ttttcatgtt tttgattttg gtaaccgaat
     1321 ccttcaactg cttcaccgat tttgtgttca ccttctgatt tgcttaagcc aaaggtttgt
     1381 ccgttttttt ggacaaagta gtttttttca ttttcatcaa taataatacc tgtaaatata
     1441 gttgctaata aatcgttcat ttttttctcc ctctatagtg aaaggttttc ttaatacatt
     1501 tctttgctat cataacataa tgttatctac ttgaatagct gagccttggt ttggaaaggt
     1561 gaaaaaagga gtatgacaac agttgtgtca tactcccctt tttcgaataa acggtgttaa
     1621 acggcaggct cacagcctct ttcatttgcc taaaattaat tgctcccatt tcctccgaac
     1681 catccagttt tacagttgat ggttacgatg taaaatggca aagcactttc tccaatgcct
     1741 ttcatcaatg cagattttgt tgaagtggca tatagattat aatagccttc cccattttcg
     1801 attctggctt tttctaatct gtaacctcct tcaacgatat atccacgttg gatacatgta
     1861 gcaatcactt tgctttggac acctggtgcc cacgtccatg ctggattaga tgcatcggca
     1921 atatcacttg ctctggcaga tttgattggc tgattcgctg agtttgaaga ggaaggggtc
     1981 gaggatgccg cttcttgctg tgctgcttgt gcgaccgcag cttgttgagc ggcttgagct
     2041 gcagctgctg cttgagcggc ttgttttgct tgttcttcag ctgctttttt cgcttcttct
     2101 gcttttttct tttcctcttc ttcttttttc tctttatcag tgagcatctt atctacttgt
     2161 ttcaattgtt cattcaactg agcagataga tctgtatttt tcactttttc tactgcttct
     2221 tttgccgtct tgtattggtc gcgtgttgct gaatccacta cttttccgtc tttaaagact
     2281 atagctgttt tttctttagc tgtttgcaat tcagcatatt gatttttagc ttctgtttgt
     2341 gcttgttgaa tcaattttcc aaaatctgtg ttatccgttt cgattgcttg gatctcttta
     2401 tctgctttca acttgatgtc atctgctaga tgatcatcga cgatggcagg tgctatgaac
     2461 cactcattca ctttttggat atctcggatc ttagattgga tatcttggta agttgtttct
     2521 aactctgaat atcctttttc attcttaaga ctggataaat cattttttag ttttgataaa
     2581 tcttgatgaa tcatatctgc acgaataaat tgatggtgat catctgtata aaaggcagca
     2641 agtttctcat gaagttcttc catttgttgc tgtctttttg cttctgctgc tacttcggct
     2701 tctacttttt gatgatggtc ataataagcc cagcttcctc caccgagtag aagtactgct
     2761 gctaaaacga gataaggtac tttttttgat tttttctttt gcgctttatc tggatctgtt
     2821 ttttctaagt ttgattcttg atgtgttttt tcagtatctg gcacgattgt tattgatttc
     2881 gcttctgctt caaacagctt aggctggttc tcttcttttt ctatttttgc ttcaagatca
     2941 gtaccctctt tgcttacaga ttgattttca gcatcggatt cactatttat ttcatcgggc
     3001 tctgttgact ttttgtctgt gttttcgagt atttcttttt tctctgcttc cggcagttta
     3061 ttcgtttttt ccttttctaa ttgtttttca gtaaatactt cagttttttc tgtgatatcc
     3121 gtttttacgt cttttatttt tactgtttct ttacctgtgg cgttttctct atcagagtct
     3181 ttttcagttt cttgttcctt ttctggctct actttgtttt cctgtgcaat tttttcactg
     3241 atcattttga gcagctcttt cgcgtgctct tcttttgtat cttcacgatg tgctttgata
     3301 taagcggata gtatcgaatt ttcttcctca ttatcgacga tttctttcag ttcagctact
     3361 cttctttttt gttttgattc aagcgtttct tcttgattct ttcctgattc ttccgaagtc
     3421 tcatgaacag ttgctttctt ctgttcattt ttctctatat tagttacttg atcgtgagca
     3481 ggtggttctt cgtcttctgg ttctgctttt tcgaataatt ccattacaga ttctagaggt
     3541 aaatctttca attccgacca ttcgattgga tcgtttaatt ctgtatcagg aaagactgca
     3601 tcttcagttg atttatcctg catagctgca tctgtatttg tttcttcaat tgattctttt
     3661 atttgctgat cttctgcagt tatttgatga ccgcagtctg gacagatagt attctgctcc
     3721 atttttttcg atccgcaatt tggacatttt ttcatcactt agcgatcggc tcctttacta
     3781 ggtttacgct accatttaat ctatcatatt ctatacgtca cgccaatagc ttatttttag
     3841 gatttactta aaaataatga atgaatttcc ttcctataga aaaaaaagct tgagactgcg
     3901 tagtctcaag ctttttttct tttaaaataa accaaacagt tttactgatt tctcttctgg
     3961 tcaatagtcc acgcttattc taagaaatct tttaattgtt ttgaacgaga aggatggcgc
     4021 aattttctta atgctttagc ctcgatctga cgaatacgtt cccgagtaac accaaatact
     4081 ttccctactt cttccaatgt tctcgtccgg ccatcatcta aaccaaaacg taagcgaagg
     4141 acattctctt cccgatcagt caatgtatct agtacatctt ccaattgttc ttttagtaac
     4201 tcataagctg cgtgttctgc tggacttgtt gcttcctggt cttctatgaa atcacctaag
     4261 tgagagtcat cttcttcacc gattggcgtt tcaagggaaa caggttcttg cgcgattttc
     4321 aagatttctc ggactttttc tgttggaaga tccatttccg caccgatttc ttctggcgta
     4381 ggttctcttc caaggtcttg cagcaattga cgttggatac gtatcaattt attaattgtt
     4441 tcaaccatat gaactggaat acggatcgta cgtgcttggt cagcgattgc tcgagtgatg
     4501 gcttgacgaa tccaccatgt agcataggtt gaaaacttaa atcctttgcg gtagtcaaat
     4561 ttttcaactg ccttcatcag tcccatgttt ccttcttgga tcaagtcaag gaactgcatg
     4621 cctcgtccta cataacgttt agcgatactt actactaaac gaaggtttgc ttctgccaga
     4681 cgctgtttcg cttcttggtc gccttcttcg attttcaatg ctaacgctac ttcttcttcc
     4741 gcagttaaaa gggagacacg gccaatttct ttcagataca tacgaaccgg gtcattgatt
     4801 tttacaccgg ttggcgcaga aagatcttct gtttttgctt gttcagcttt tttctcagca
     4861 ctcttcaagc tgtgaattga tggatcacca ttttcatcca ccacactgat acctgcgtct
     4921 tcaatctttt ggatcaattt gtccatttca tctgcattca aagtgaatgg tgtagcaagc
     4981 tgattggata aatcatcata tacaacttgt cgtttgggtt tgttttcttt gatgaaagct
     5041 gctactgctg cttcatacgt ttttttatct gttccatttg ccataaaaga aggcccccct
     5101 tgagtagcta tttggcttgt tttaactgtt tcgttaaatt gatgatttca atcgtcaatt
     5161 caagctcaag ctgtttgttt ccagttcgtc tggcttcttg ctgcatttgt ttttttaatg
     5221 ttatttcatc agctaagcca gatttgctga tcacatctag caagtcttgg atttctcgtg
     5281 gcgaactttc ttctgccacc ggtaaatatt cgatttccac caccaaccgc cttaaatttt
     5341 catcttgcaa aaagtctaaa aactctgcaa ggttgaattc ataatgttgt gagacatatg
     5401 catcgaataa aaaataaact tctgcatatg catcatgaat aaactgaaat tctcgttctt
     5461 ttaaaatatt acggacagaa acttctttaa atgcacgata taatagaatc tgctctgcct
     5521 tttctacttg cgtcaaaggt ctctttttcc gtgcagtttc ttgtctcgta acctgagtgt
     5581 gttgactttc ctgaggttct tgacgatttt gctgatttgt ccttcgaaga tcgcgcagtt
     5641 gtttttgtat cgtctctctg ccgatctgaa actctgttga cagttgagat agatacatat
     5701 cttgttcgat tggtgaaaca actcggctaa gttcaactag taattcttcg aggtattcga
     5761 tcttgtcttt ttcattatct aaatttttcc cttgttttaa ataacgtgat ttaaaagtaa
     5821 agactgtttc gcgcccatga gccactaatt cttggaaaga tgcttctcca tacttacgga
     5881 gatattcatc aggatcaagc ttttctggaa cgactacgac agaaagtgct aatcgactgt
     5941 tttgccgaag caattcaatc cctcgattgg ttgcttcaaa acctgcgttg tctccgtcat
     6001 agcaaaagac caattctttc gtcagctttt ccatttgttg gatctgttga gctgttagac
     6061 ttgtccccat agaagctaat ccagttttga taccagcctg ccatgcagca atcacatcca
     6121 taaacccttc gaacaacaaa atttctccgt ttttccggat atcgcttctt gctttatcaa
     6181 gattaaataa aacttgtctt ttattgaaca gttctgtttc tggactattc aagtatttgg
     6241 gctgatcttt ttcctgccct ttttcaggtg caagccagcg tcctgaaaaa ccgatcgtct
     6301 ggccttgaga attacgaagt ggaaacatca ctctttgata aaaacgatca gacatacggc
     6361 catcatcatg cgtgacaaac aatccagagc gttctaacaa ttcatttgaa attgattcat
     6421 tcttgaatac ttgctgaaga aaagaacgct cattaggtgc aaaacctatg ttgaattctt
     6481 caattaattc taaagacaac ccacgacttt gcaaatattc taaagctggc tgtccagctt
     6541 ttgtatgcaa tagcatgtga tgatagattt ccgctgcttt ttcatgagca gcaatcagtt
     6601 tccccgtagc agattcagga ttttggacag ctatagtacg ctgacgccat tgatcttcta
     6661 acggtatctg ttcgaagtct gccactttta ccactgcttc tggaaaactt agaccttcta
     6721 gttcttgaag aaaagtaaac acgtttccgc ctttaccaca accaaagcaa tgaaaaatct
     6781 gcttgtcttc tgcaacagaa aaagacggtg tacgttcttc atgaaaagga cacagcccca
     6841 agtaattttt accagacttt ttcaactgga catattgtcc aatcacctca acgatattcg
     6901 tttgactgcg tactgtttcg ataacctctt gaggaatccg ttgagccatt ttttcacccc
     6961 ctgctctatt gatatctttt gggtttaaca gaagatattt caggagaata accggtaaaa
     7021 aatcgcacta actgaaatca gtgcgatttt aaaggacaca attatacatg tttgattgta
     7081 tcatatttca ttgctttttc aagtataaca catttctatc tcattaagca tcaatttgct
     7141 actcttttca gtaactgatt ttgaatatca gccttccagt acaatactcg aagaacaata
     7201 tttacgagca tgaatacaaa gaagtatcct acgctctctc ccaaccctaa gtttacttcc
     7261 aaaattccat ggaacagcat tgcagctaca tatatcccta cgatcgtcgt tactgctagg
     7321 aagatgcgca atgggttgaa gggataacaa gcttttacaa ctgccatgca actgatccca
     7381 atcagcaagt aatacatcaa agtagtagtt tcagcatttc cccatgcgaa tgtttttcca
     7441 agtagataca ccgcaatgat attcactact acaagcaagg catttggtaa agcattaata
     7501 agtgctgtag gcaaataacg gtaagtgatt tttcttttat cttgttcaaa agataaaaag
     7561 aaggaaggat acccttcaat cgctaaatca atcagcgtga tttggatagg gataaacgga
     7621 aatccaattg ctgtaacggc acatataatc gataaaataa atgaataaat cgttttgata
     7681 aaaaagatgc ctgagacttt cgtcacattg ttgaccactc ggcgtccttc aaacaggact
     7741 tctggcaatg tagtaaaatc agagtccaac aataccagat tcgcaatctg acgtgttgct
     7801 ccatcacctt ctgccatagc aatgctgcaa tctgcttctc ttaacgccaa aacatcattc
     7861 acaccgtcgc ctgtcattgc aaccgttctg ccgctttctt tcaattcatt taccagcaat
     7921 ttcttttgct gcggactcac tcgtccaaaa accgtatagc gatgagcagc ttctcgcact
     7981 tccatttctt cagtaatttg agaaagatcg acatacgcat cataattcgg taatcctgca
     8041 cgtctagcga tattggagac agtaaaagga ttgtctccag aaatcacttt cagatccaca
     8101 ccttcctcat gaagataagc tagtgtttct tgagcgtttt ttcggattgg atcatcgatt
     8161 tcaaacagag caaccggctc aacaaatgct ggtttttctt cgttcaattg ctgatttgga
     8221 gcgatcccca acataagtac gcgatagcca ttcgcttggg ctgtttttag actgtccgga
     8281 agccgatctt cttccaccaa acgttcaggc gctcctacgt acacgactcc cagttctgga
     8341 aattccatcg cgccccattt gcgatcagaa gaaaatgcga ctttgtttgt cacatcatac
     8401 cgattagaaa gctcaaaata atctctcata gcccgcatag tgatgttgtt atcactgctt
     8461 tctgccagat acgtccccat aatttctggg atggctttct cgtacagcgg atgtagtgct
     8521 tctacccgct ggatactcat tttcccttca gtaatggtcc ctgttttatc caagcataat
     8581 gtatcgacat gggccagcgt ttcaattgaa tacatgtctt gaacaaggat tcgttttttt
     8641 gccagtttgg ttacccctgt cgttaatgca atacttatta gcaataccaa accctttgga
     8701 agcatgccta acaaagctgc tgcagatgca ataacagaaa ttttgataga agcatcgcgg
     8761 atgaacagtg cttccaaaaa tagtatgatc cccaaaggaa taatcacgaa actagtgaat
     8821 ttggatactt tgcgaatcga atctacaagt tcagaacgaa tagctttgtg agtctttgcc
     8881 tcgctagtca agcggacagc ataattatct gcacctactc ggataacttc agccatgaca
     8941 gaaccgcttg tcaaaaagct tccagaaagc aattcagctc cagtttcttt gacaatcaaa
     9001 tcagattcgc ctgtcaaaag agcttcattt gcttctgccc gtccagatat aacctgtaaa
     9061 tcggctggta tctgttctcc tgctccgatt tttaccaaat ctcctaatac cagctcttta
     9121 gtagaaatcg attgttcttt accgtcccgg atcactagta cttctgattg ggaaacaatc
     9181 gataatttcc gtacaagatt tcttgcatgt atttcttgat aaattccaat aacgatattg
     9241 acgacaataa ttgctaaata cgccatgttg gaatacgcac ctacaaataa cagacaaatc
     9301 ccaataccaa agttcagaaa attgaataac gtcaatatat tatcgctgaa tatttgtttt
     9361 gtactttttg atgcatcttc ctggtagtca ttttgctggc cagaagccat tttctgaact
     9421 acctcttgct gtgtaagtcc attcattttc tttttctcca ttttccgcca actttcaaaa
     9481 ataatcacgt gtttaagtct agcgtgttcc aagattaaaa acaacttgtt tttataaaat
     9541 ttatagaaaa acacacgaat gattttacaa aaaagatgcc aacctttttg tttgaatcac
     9601 ccgtgtgctg tttttattat caatctatct ttacttatat tgttcctcca aacggctcat
     9661 ccaccaacct agtgctgtac cggctataaa aagaacagga caagctagta ccccagcaac
     9721 tcccaatccc gcgtaatcgg taggaatgat cataatcgtt gaagcaaaaa ctacacctaa
     9781 aatgaaatgg aatagcttgc tatatgcctt tgagaaaatg taatccatga tttttgacaa
     9841 tccaagaaca caaagaatcc caccaattcc gatcggcaca atcacttcaa gtcgtacttc
     9901 tttaaatccg tcagccatcg ctttatacaa tcccatatac accaaaaaat tagaagggct
     9961 caatcctggg acgatcatac ccaaaccaat caatccgccg gcaatcagcc atgttccaaa
    10021 attctgatcg acttgcccgt caaataattg agcgccgtat aataaaaaca aataagccag
    10081 aacaaaagta acaaccatga tgatcacatc agaagtatct cttccttttt tccctgcttc
    10141 tttccataac gcaggaacag ttccagcgat acatccgaca aaaaaccata atatcgttgt
    10201 ttcatacgca cctaataaaa aactgactaa aaaagaaagt agaaagatgc ctgtcactcc
    10261 gcctagacca acaggcagaa aaaacaaaac attttctttg aaattttttg taaggtgggc
    10321 taaaaaagaa atcagccgct catacatgcc aaagacagct gctaatgcac caccgctgac
    10381 tcctggcaag ataaatcctg aaccgataaa cattcccttc acaaaccgta acatccagtc
    10441 tttggttgtg taccccactt cttgattttc cattttttgc cttttttcca ctatttgcgt
    10501 actccttctt tcatttaatt ttattcatga ttgaacattt cctgctattt tacttaaaga
    10561 ctttttcata ggtctctatt attttttcat tcattttgac aatatcagga taaaacatgt
    10621 tacctccatt atgatagaga tagccgccat tgtaaagcaa ggactggatc cgccaatatc
    10681 ggtattgttt cccttcctca tttcctaaaa gtgggctcag cacatcttta gaatacgctt
    10741 ctgctaattc tactgtgttt tctccgccat gattttttac ataggcaata taatctttcc
    10801 caaaattata tgcttggaca gctgtccata aatcgcatcc ttgtttcttt gcttctacta
    10861 tcatttccgc caaatatttg acaccttgat caatactgtc agctggatta tcaatgatct
    10921 cagcttctcc atgcagactt tccgagctct gcatgagatc tgtccctttt ccttttgatt
    10981 cggtcaatat tatcgccttg atcaaattct cgtagttttc catatgataa ttttttgcag
    11041 ctgttgttat ttctatttga tagctttcca ctcgttttac cgaacgataa gttcttcctc
    11101 ataaaaacaa caccgcacca ataaccgtca gaatgatcat gtaaaaaaga atacggataa
    11161 tagataatcg ttttcgcttc atttcatcac ctagttattt tgacatcttt ttttatctta
    11221 ctatttcttt atcttcttgg ctatttcttc cttgatttct gtgtacgcct taagaaaaaa
    11281 tgaattttcc tgtatttttt gacatcttac gaaaatgatc gttgtttttc agtaaaaaca
    11341 attgcccaat gactgatata atcgttatac tttacacagt aggtgattat gtgaaaaaag
    11401 aaaagaaata tgcaaaaatg ccagatggga gcgaaattta ctatgaaaag agcggtcaag
    11461 gcttccctct ctttttactg catggcaatg acggcagcgg ccgctttttt tcagaacagg
    11521 tccctgtact cgaacgctac tataccgtgt atctagtaga tagccgagga catggtcgtt
    11581 cgacaaacga agcatctatg ttgaattttc agttaatggc cgaggatctg aatacgatca
    11641 tgttgctgga aaaaatcgat caggcagatt ttcttggatt tagtgatgga gcaaatctag
    11701 cactggtatt tgccagcagc ttccctaaaa aagttcatcg attgatttta aattctggaa
    11761 acacgcttgt taaaggcgtt cgtttttctg ccagagtcat cagtaatatt cattatgcat
    11821 gggtatggtt actctcttta tttcgcccaa gtcttcgcaa aaatctttta gttatcaaac
    11881 ttttgctgca tgacatcggg cttacagaaa atgatttaaa aaaaatcaac tcccccactt
    11941 tgatcatcgt gggaaaaaaa gatgtaatca agctaaaaca ttctttgtat atagctaaaa
    12001 ctataccaaa agcttccttt gtgcttgtga aagaacaagg acatgaatta gctagaaaag
    12061 atcctgaacg cttcaatcga gaagttcttc aatttctttc tgaaacataa ctattaggaa
    12121 tagaaggtga tttatttgtt aaaaaatacc atacaatggc tgaaaaacca cctaggactg
    12181 ttcaaaacaa tctttttgat ttctgtcatt gtcattattg tcggtgaatt gatgtccatc
    12241 ggtaaaactc tatctatcca gcaattagga gaaacgtttg ccactatacc tgtatggaaa
    12301 agcggactaa tgctattgat tggtcttatc tctgtgttac ctatggttgg ttatgatatt
    12361 attttgaatc ggatgcttga acaaaagcag aatcctcgtt acctgtttga gacaagctgg
    12421 ctgatcaata cgatcaacaa tattgccggt ttcggcgggt ttgttagtgt ggggcttcgc
    12481 tctgaactat atggacaaaa gaaagagagc agaaacgtga tccaagcatt atcgaaagtt
    12541 ttcttgtttt tgatggctgg actttctatt tacagtctgc tttctttttt acttgtagtc
    12601 ttcacgccag ttgctccttt tttgaagcaa tattggatat ggttgatcgg cggcggtcta
    12661 tattttcctg tcgtcttttt atttactact ttcaaaaaga aaggattcct tggtggtacc
    12721 tcacttaaaa ctcaaggaca gctattgcta gtttcattgt tggaatggac cggtgtcctg
    12781 tttagtttcc tttctgttgg ttatttaatg gaaatccgga ttgatctgtg gcaaacaatt
    12841 ccattattca ttgctgcttc agtgatagga atcgtgtcta tgattccagg agaaattggg
    12901 agtttcgatg taatgatgat tatcgggttg tccgctattg gtgtgccaag agaaatagtc
    12961 gttgtgtgga tcttgctcta tcgcctgttc tactacatca ttccgttttt gattggaatc
    13021 gtctttttct tcaaaaatat cggttccact tttgatcagc gttattctgg tatccctaaa
    13081 caattagcaa cagaaattgc gcataaaatc gtggttgtct tattatactt ttctggaatc
    13141 atgctagtac tttctgccac tatcccgcaa gcttttacag agtttcgctg gcttcatagt
    13201 ttgaacccat tgaaatttca ttttattatc caatttccta gtatactatt gggatttctt
    13261 ttaatcatta tgggcagagg gatcgcagca cgtgtgaaac gagcatattt gcctacaatc
    13321 ttcttgattg ttctagcttt actttatgtt ttattaagtg attttagttt cacaccggtg
    13381 gttttcttgt ctattctgct tctgatcatt cttgcttcta aaaacgaatt atttcgggaa
    13441 caattgatct attcatggga gtggcgtacg atcgatggaa tcattattgg tgcactgtcc
    13501 ttgctttaca tcgttattgg ggtatacaat ctgccggatt tccctcatcg gcgtcaccat
    13561 tttatttcct ttttcttatt tccttctgaa aagatttggt tttcgggatt gttggccatc
    13621 atcgctgtta gtttcatgat cgttctattt gttcatttcc ttcaaggaga aaagaaacag
    13681 attggcgaag cctttaatga agaaaaggcc ctgaagatcc ttacaactta tggaggaaac
    13741 tccgatagtc aattgatctt cttaaaagat aagcggatgt ttgcctatga aaaagacggt
    13801 gaaccaactg ttcttctcca attcgcttgc ttcaataata aatgtattgt aatgggtgat
    13861 ccttctggta agaaagaaga ttttccagaa gcaatcgaag cttttatcga agaaacagat
    13921 cgactatgct atttaccagt tttctacgaa acaagcgaag agattgttat gattttgcat
    13981 gaattcggct acgatttcat taagatgggg gaagaagctt atgtagacct gaatagtttt
    14041 acaacttcag ggaaaaaaat gaagggcact cgtgctgtct tgaatcggat cgaacgagaa
    14101 ggatttacat ttgatgtctt acaaccacca ttttctactg agcaaatgag tactttcaaa
    14161 aatatctctg ataattggtt gggttcacga aaggaaaaag ggttttcttt aggctttttc
    14221 tctgaagatt atctacaaag agcgcctatt gcagttgtca aaaataccca agaagaaatt
    14281 gtcgcttttg caacgatcat gcctacttac acgaacaata aagtaggaac gattgatctg
    14341 atgcgatatg attctaaaaa agcaccttct ggcagtatgg atttcttgtt cttgcatttg
    14401 tttgcctata tgaaagaaga acatatccaa tggttcaatt tagggatggc ccctctttca
    14461 aatgtcggaa cttccagaaa gagtttttta caggaaagga ttgcatactt ggtttacgag
    14521 tttggttctc atttttattc tttccatgga ttaagagaat ataaaagcaa gtacgctaca
    14581 aactgggtct cacgttatac tctatattct agagatagtt ggattgcata tgttatgatt
    14641 gctttgctga ttattgataa tgcgccagtt gagcagacac aaggtagaat aagtggtttg
    14701 aaaaaatgga tacgaagaaa gtattaaaaa ctgcataccg atagatgaac actctcatga
    14761 tgaataaaag agactgaagt aaaacgaaag ttcatgcttc tacaatctct tcttatacaa
    14821 ttgaagaaca aagagcggtc caaacagaaa tcctgtttgg accgctcttt tattttaaac
    14881 atttttcatt accaaaatat tcgagtcgcg tttcttatgc ttcgatctct gtaacgatac
    14941 ctgaacctac tgtccgtccg ccttcacgaa ttgagaatgt cgttccgttt tcaacagcga
    15001 ttggatggat caagtcaaca tcaatcgtca cgttgtcacc aggcatgacc atttctgtat
    15061 cttctggcaa tgtgattgtt cctgtaacat cagttgtgcg gaagtagaac tgtggacgat
    15121 agttgttgaa gaatggagta tgacgtccac cttcttcttt tgtcaacacg tacacttctg
    15181 ctttgaattt tgtatgtgga gtaatggaac ctggtttagc aagtacttgt ccacgttcga
    15241 tatcgtcacg ttggatcccc cgtaacaaca cgcctacgtt atccccagct tccccgtaat
    15301 ctaacgtttt acggaacatt tctacacctg ttacaactgc tttttgtgtt tcaggtttga
    15361 tccctacgat ctctacctca tcaccgacac gaacagcacc acgatcaata cgacctgagg
    15421 caacagttcc tcgacctgta attgagaaga cgtcttccac tggcaatagt aatggtttat
    15481 ctgtatcacg ttctggtgtt gggatatatt catctactgt atccatcaat tccataatag
    15541 cagcttcagc atctggatcg ccttgcaatg cttttaatgc ggaacctttg atcacaggag
    15601 tgtcatcgcc tgggaaacca tattcgctca ataactcgcg aacttccatt tctaccaaat
    15661 cgatcaattc ttcatcatcg actaaatcaa ctttgttcaa gaaaacaatc aggtatttta
    15721 caccaacttg gcgtgacaat aaaatgtgtt cacgtgtttg aggcatcgga ccgtcagttg
    15781 cagaaacaac taagattgca ccatccattt gtgctgcccc tgtaatcatg tttttcacat
    15841 agtccgcgtg tcctggtgca tcaatatgcg cgtagtggcg tttttctgtt tcatattcta
    15901 cgtgtgcggt attgatcgta atcccacgtt cacgttcttc tggagctgca tcaatactag
    15961 catagtcttg aggatttgct aggccttttt tgcctaatac tgtagtgatc gcagcagtta
    16021 aagtagtttt cccatggtca acgtgtccaa tcgtaccaat gttaacgtgt ggtttacttc
    16081 tgtcataatg ttcttttgcc ataatttaca aacctcctaa ataatataga tcactgaaaa
    16141 atttcagctc tcaccttttt attatagtct ttttttgact aaatcaaaaa gaatacgtcc
    16201 gacttacttt ttgtaagatt cgaactaagc ttattatacg tcaatattgg tcaaagtcaa
    16261 ctaagagcac tcgtctgtct tatacgcgaa aaaagtacct tttataaata aaaaaatgtg
    16321 ttttttgaga aaaacttcaa gatagtcctt aactttcttt tgaagcaata agaacaaaat
    16381 gaggaaaagt ttaaaattca gctgttgcca acaactttca atagacgaaa tcttctattt
    16441 cgttaataat aaggaaagag gtgaagtaca tgaaaaaatt aattggcgta cttgtcgttt
    16501 taggcatatt tctcggcgga agttttgcag cttatcatta tttttacggc ggcgaagctt
    16561 attatacaaa aatcacgacg aatggcgaaa tgtcagctac ccaagcagat aacggagaga
    16621 aattcacgac ttatacctac aagcaagcgg cttataataa agatggtgaa aaaaaacagg
    16681 tgacgcttcg cgaagaaaga gaacatccat taaagatgaa tgcgtatctt aaactcaaag
    16741 tcaatcctcg taaaggtgta ttaagctggg aagaaataaa ggcttctgaa gtgcctaaaa
    16801 atgcggcaga aaaaatcgat aattagtaaa tggtcttaaa attttattag ataaaaagag
    16861 gctgggacag aagcgtttaa ctccaagaaa taagaaggag ttgcttctgc ttccgccgtt
    16921 tatacgtgtt tagagcgtga gacaaaagtg ttctttactt ttgtctcacg ctcttttttt
    16981 gttatattcg tcttttccga tccttctctt gacacaattc atttaactga tcactggtac
    17041 ttgaacacct aatattctag tcatttttat aaacgattca atacttcatc cacatttttg
    17101 atcatcacgg atatcgtacc atccggatta ttcacaaatt caatcaaatc tgggttgcga
    17161 tatacatcta ctggtacgat cagttcgatc ccgtttgata gcttgaattt ttgttttcca
    17221 aattttttct cagaaatttc ttgtacttct tttacaggag gtgcttctgg gacaaatcct
    17281 tgctcttgta cttcttcttt aaaagccatt tttgccgtga tgttttcctt gaagactttt
    17341 tccgcaatca tctcatgatc caaccgacct ttttcttcta tcgtatcata gacagcttct
    17401 ttcaaatcag ccatgatatc aaattcttct gtctcaaatt tttttccaag atgcttggct
    17461 actttttgga tcacttttac attttcttct aaagaaggtg caggaacact ttcgatcact
    17521 cttccagaaa aataaagctc ttttttgcca gaaaactcat attttttttc aattaattcg
    17581 taggtccaat cagtcaaatt cacagcgaat gcttcatctg ctttttgtgt tttcgcccct
    17641 agaattgctc gattcaaaat caagcggttg tcgatccctg cttcgtctgc ttcaacaaag
    17701 tgagtgtaag cctcacgata attgactttc aataaagata agtacatcac tgtatctaat
    17761 tcatacaaga caacaaatac atctgcacta ggtgcttctt cactttcttg gtagatatcg
    17821 aaccaccgct gaacgattgc ttcacttgct tccacaaaat tttcttgagc gattttaagt
    17881 gattcaacga tcatgctttc ttctgctagt tgtccagttt ttgtttgagc agaagagatt
    17941 ttttggatct tcttttgaag aaaatcacga atatattctt ttgtcagatc cagctctttt
    18001 tgtgaaaaga ctggagaacc agtttctctg tcaataatat gcagaattgc tttttttaaa
    18061 tagatatcca ttttctcatt cccttctgtc ttagtttacg gaaaaaaaat caaaaatacc
    18121 agaatcaaaa tcattttctt ttaaacaaaa atttcaagag tagaaacaaa atggattctt
    18181 tttttcgaaa aatgcgctac acttatagtt gaacgaataa aaaaggagct gaaagtatga
    18241 attcattaac aagcacttat cgtctatcaa atggttacga aatcccggta gtaggattcg
    18301 gcacatggca aacacctgat ggggatgtcg ctgtttcctc tgttaaagaa gcgctggctg
    18361 caggttatcg ccatatcgat actgcccaag gatacaagaa tgaagaaagc gtcggccaag
    18421 cgattaagga aagtggaatt cctagagaag agatattctt gacaacaaaa ttatggaatg
    18481 caaaccacag ctatgaactt gtgatgtctt cttttgaaga atcattgaag aagctccaaa
    18541 cagattattt agatctgttt ttgatccact ggccaaaccc tgttgctttt cgtgataatt
    18601 gggaacaagc aaatgcagat acatggcgag catttgaaga actgtatgaa gcaggtaaaa
    18661 tcaaagcaat cggtgtgagc aatttcttac cccaccatct agatacacta gcaaaaacag
    18721 caaaaattat gccgatggtc aatcaagttt tccttgcacc aggcgaatta cagacaactg
    18781 tagttgagta tgcaaaaaaa catgatatga tcctcgaagc atatagtcca ttaggcactg
    18841 gtaaaatctt cgatgtgcct gaaatgaaac aaatcgctga agcacatgac aagacgattg
    18901 cacaagttgc tttgcgttgg tcgctgcaac acgaattcct tcctcttcct aagtcagtga
    18961 caccaagcag aatcaaagaa aatactgaat tatttgattt tgaattaaca gaagaagaaa
    19021 tgaaacaaat cgatcagtta gatggtgtag tcggcaaagc aaaagaccca gatactaccc
    19081 aattttaagt cgaaaggtga ttttatggat ccaatcgaac gcttgaattc tctctcggaa
    19141 gaagttaccc agacttttca ttccgatttt gtctttttga tcgatgcaga gaaaatccaa
    19201 cattttcctg caagaaactg gacacatgat caaatcatcg aagaactgaa aaaacggttc
    19261 gatcattcgc taatggtcaa accctggcac gaacatgaag tcatttattc acctgaacta
    19321 cctgtttttg ccttgatacc gaaaaaatag aaagaatgga acggattatg tatatataca
    19381 taatccgttc cattttttat ttttctttca aaaaacggga aaatacgcaa atttttctgt
    19441 tgtaatttgc gtatacgcaa gtttttttgc attactcctt ttcatttggc tgtttttttc
    19501 ttataatcga aagggtatga gcgaaggaga gaacatatga agaaaaaaca gaaacaaaaa
    19561 ttattaaatc aattccgtcc ttcattggat ggtgtaagag gacaattatt ccgttctcta
    19621 gaagaagaga gcttgcgacg ttatggtttg ccgttacaag tcatgcttga tcccaaaaac
    19681 cgtcaaatct taacgatcgg attagctggg aaaacaaatg aagatacacg gatcaacgtg
    19741 ccaatcgatg acaacttcaa tactgtatta aagagaattc gttcaggaga aaacgggatt
    19801 ttcgaacgat tccgtgacaa tcttcttatt gaaatcgtgt cttactggaa tgatcaacga
    19861 ttgaaaaacg atgaaccaac tgcgcaagct gttgcgacac cagttacaga agaaacagtc
    19921 agtgtgccag aagaaaaaac ggaaaaacca aaagcggaca caactgaaaa tacacgctca
    19981 actgatacga atgccgcttt aagttttgct gatttttcaa aagccgttgc tgagtatcct
    20041 aaattttaca cagaacaaaa tgaacatgaa gtagttatta atgaaaaaaa tgctgatgaa
    20101 cctcgtaaat tagcaactat ttctatgact actgaaaatg agttcgttat cgaaaaagca
    20161 ctcgaacgga aatacaaagt caaattgact ttgattcctt tgatcgaaca atttgcagcg
    20221 acagcgatta ctgatcgata aaaattctat ttgtcataaa aggctgggat ttaaaatccc
    20281 agccttttta gtcatataat aatttctaca gcaagtaaaa agaaattcct tctaacatca
    20341 ggctcaaata tcagcttgac ctgtccaaca aatcacctat gatcctacaa tgttaggcga
    20401 cttctcttct acctgaagat atcttggagt tgcctgattt cttaagatgc ctaaccttaa
    20461 ctataaaaaa ttctaataat aaacatattt tctgatagag aaaaaa
//
LOCUS       DAZKKZ010000053        19847 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.054, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000053 DAZKKZ010000000
VERSION     DAZKKZ010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19847)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19847)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19847
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.054"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            168..362
                     /locus_tag="ACG8LA_002064"
     CDS             168..362
                     /locus_tag="ACG8LA_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204355.1"
                     /translation="MYYVEVKTKGVKNKQYVKGISNEYPLLGSWKEAAPFSKPCAIKI
                     KNELEKELTCGKAVVDIIEK"
     gene            631..930
                     /locus_tag="ACG8LA_002065"
     CDS             631..930
                     /locus_tag="ACG8LA_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204356.1"
                     /translation="MDYTVEFDSELLKQFPQEEHFMYKEAISHKVTEYLEHNFFRIKP
                     VRTRSAKGIYEMKVKINKKNYRIAFALKKNHVFIFYISSNLQKIVFDKEVSKKIK"
     gene            complement(1027..1461)
                     /locus_tag="ACG8LA_002066"
     CDS             complement(1027..1461)
                     /locus_tag="ACG8LA_002066"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFQ0204357.1"
                     /translation="MNIDSLMIDEISELYKSVGWTNYTKDTARLARAFEQSESLIKRN
                     GEGKIIGIVRWITDFATIAFIQDILIHPRYQRQGIGKVLLNEALEKITSYGPVQIELL
                     TDDTEKTKKFYESVGFVQVKEMGGISYVIDTRRKKVLFGNDK"
     gene            complement(1693..2403)
                     /locus_tag="ACG8LA_002067"
     CDS             complement(1693..2403)
                     /locus_tag="ACG8LA_002067"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0008742 - L-ribulose-phosphate 4-epimerase
                     activity [Evidence IEA];
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0019569 - L-arabinose catabolic process to
                     xylulose 5-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HFQ0204358.1"
                     /translation="MSCEEKIAAMKQRVLEANLALPRYGLVKLTWGNVSEVDRELGVI
                     VIKPSGVRYECMQADQMVVTDLSGNIIEEDSLKPSSDLPTHVVLYQTFEDITAITHTH
                     STHSVMWAQAGRDLPAYGTTHADAFYGKVPCTRQLTKEEVREAYEVHTGNVIVETFKE
                     RKLDPNEVPGVLVYGHGPFTWGDSPMKAVENSLILDEICLMAKENELINPNICEIPQY
                     LLDKHYFRKHGKYAYYGQ"
     gene            complement(2393..3253)
                     /locus_tag="ACG8LA_002068"
     CDS             complement(2393..3253)
                     /locus_tag="ACG8LA_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016861 - intramolecular oxidoreductase
                     activity, interconverting aldoses and ketoses [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HFQ0204359.1"
                     /translation="MAQIGIYEKALPKDISWKERFSLVKEMDFDFIEMSIDETDERLA
                     RLDWSEEKIAELREEMFSSGVRIHSICLSAHRRFPFGSADPEKKKAAKQLMKKAIHLA
                     HNLSVKVIQIAGYDVYYEEKSMNSREDFIEGIKESVKEASKYGIILSVEIMDDPFMNS
                     ISKFLEIKEQIHSPFLQVYPDLGNLSAWPENNPARELEKGIDYITAIHLKDTYPVTKE
                     YSGQFRDVPFGSGCVDFLGLLRHLKRLDYDGTFLIEMWSEKSQDFRREIQQAKDYLSS
                     KLKEAGYDVL"
     gene            complement(3258..3896)
                     /locus_tag="ACG8LA_002069"
     CDS             complement(3258..3896)
                     /locus_tag="ACG8LA_002069"
                     /EC_number="4.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HFQ0204360.1"
                     /translation="MSRPNLQIALDHNDLEHALGDVMKVGDVVDIIEVGTILCLQEGQ
                     KAIRCIRSMFPDKKLVADTKCADAGGTVASNVAKAGADWMTVICCATIPTMEAAQKEI
                     GELQVELYGNWTFEQAMDWHNIGIRQVIYHQSRDALLSGETWGEKDLSKIKKLIELGF
                     NVSVTGGLNPHTLHLFEGIDVYTFITGRGITAANDPMKAAQNFKDEIIRIWG"
     gene            complement(3911..4210)
                     /locus_tag="ACG8LA_002070"
     CDS             complement(3911..4210)
                     /locus_tag="ACG8LA_002070"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFQ0204361.1"
                     /translation="MRILVSCANGSGTSLMMMRSVEKAMKELNVPITKIHHCAISEGK
                     SSAGQYDVVFTPVNFLNMFTQAEKKGVTVIGIKNVMSVKEISEKFAETKWYQKNK"
     gene            complement(4253..5737)
                     /locus_tag="ACG8LA_002071"
     CDS             complement(4253..5737)
                     /locus_tag="ACG8LA_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HFQ0204362.1"
                     /translation="MGEFLLSIWTYFATNILTQPAYLIGFIVLLGYILLKRPLHECIA
                     GFLKATVGYFILTVGSGGLVNNFRPILVGLKERFNLDAMVTDPYFGQNAVDAGLMETF
                     GRTFGDVMILLLIAFVLNILLVRFQKYTKLRSVFTTGNVQVQQAATAFWILLFCFPDL
                     GRIQALIFMGLILGCYWTVASNLTVGITQELTEGAGFAVAHQQMFGIFIFAKLAEWMK
                     KRDEKKNRSIKQDKKIEDIKLPGFLSIFNENMVATSLLMLFFFGIILIVLGKDYLIQA
                     QFMQEGQSFLFYIMTTSLNFAVYLAILQLGVRTFVDELTQSFQGISNTILPGAVPGID
                     VAATFGFGSPNAVTIGFLFGALGQFLMIGLLILLKSPTIVIAGFIPLFFDNAVIAVYA
                     NNRGGFKAACLFPFLSGIIQVGGSALFATWIGMSTYGGYIGMFDWATAWPLFTVIMKV
                     LGYAGIAVVVIGLLAIPQLQYRKNPDGYFLIVEDYDTYAEKQRV"
     gene            complement(5757..6218)
                     /locus_tag="ACG8LA_002072"
     CDS             complement(5757..6218)
                     /locus_tag="ACG8LA_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFQ0204363.1"
                     /translation="MLKYFFDHQLIHYPDKEITDWREAIAESCLVLIDKEIIDETYVE
                     EIIHCVEKYGPYIVIAPQVAMPHSSEKSDGVFGTAISFTKLKQPIRFESEGENEEKTA
                     SLFFTLAAKDPEEHLENIQKLSELLMTDGLVERLISTNSIDDYQVVMAEYN"
     gene            complement(6236..7303)
                     /gene="ulaG"
                     /locus_tag="ACG8LA_002073"
     CDS             complement(6236..7303)
                     /gene="ulaG"
                     /locus_tag="ACG8LA_002073"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030145 - manganese ion binding [Evidence
                     IEA];
                     GO_function: GO:0035460 - L-ascorbate 6-phosphate
                     lactonase activity [Evidence IEA];
                     GO_process: GO:0019854 - L-ascorbic acid catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HFQ0204364.1"
                     /translation="MSKTVNEVTKEKWLVETFPEWGTYLNEEIETEVVDPGTFAMWWL
                     GCTGIWLKSHEGTNILCDLWCGTGKRSHGNGMMKKGHQMMRMSGVQNMQPNLRTQPFV
                     IDPFAIKNVDALIVTHIHSDHLDIHTAAAVHQNCPEATFIGPKEVVRTWQKWGIPEEK
                     TITVKPGDAVKIKDINVVALEAFDRTALVTCEDPEEVLKGKMPQEMDQIAVNYLFETS
                     GGNLYHAGDSHYSNLFAKHGNEHKIDVCLGAYGENPRGITDKVTSVDMLRMAESLNAK
                     VVIPVHYDIWSNFMADPKEITEIWKFKKDRLKYGFKPYIWQVGGKFIYPTNKDDLEFN
                     FYRGFEDVFSIENDTPFPSFL"
     gene            7521..8291
                     /locus_tag="ACG8LA_002074"
     CDS             7521..8291
                     /locus_tag="ACG8LA_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HFQ0204365.1"
                     /translation="MKNSLVNIEKRQKEILELLQQTEQLSTFELAESLDVSISTIRRD
                     LNLLEEKNEIIRNYGYCSYNYKNQTDFDQSGPERIKQAIAREASKYINDYDTLFINSS
                     STALKTLDFLQSNHLTVITNNVKINYSPHKDNCSYILTGGEMRFPKEALVGDIALNTI
                     SSVNADICIIGCSGVDVVHGVTTKILNESTINEMMVNKTIKCKILVADHRKIGLTSKF
                     KIADISVFDYLITDKFCSEKVLEEIRNTGIKTIQVDSF"
     gene            complement(8564..9391)
                     /locus_tag="ACG8LA_002075"
     CDS             complement(8564..9391)
                     /locus_tag="ACG8LA_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0204366.1"
                     /translation="MIKVDGALLKEYRKKKGLTQVQLAEGICEQATVSNIENKNMSPG
                     INILSALCKKLNVEISDILVETEEDKIRKKINEIQSLNSVSKYQESYKILQTIDQEKV
                     SNSDLLNQILFYQGLLDHLYAKKPDAALFYFNQVLEQTTETDIHHLQAAANVAMIYLS
                     KGELDFAKVYVERTLKILSETDFDNLMVCIVYYDIATYYRKIEDYDKAIQLCEKGIEY
                     NKKHKSTYALEYLLYEIASCHKQLGEDDYLERYMDAKKIARFNGNDYAVKVIENDLK"
     gene            9959..11194
                     /locus_tag="ACG8LA_002076"
     CDS             9959..11194
                     /locus_tag="ACG8LA_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFQ0204367.1"
                     /translation="MKTILFAPAVFNLAETTRMIEVAKAMKDRYYCVFFGFSKTFAPL
                     ITESGFEYHLLAPILTKKQEEQIIKFDQLRTLKNPFTKEMVASRITSEQSLIAKFEPR
                     LIVTGSNVTIFLSARNKKIPLVYVKPYALSEPFFQSEHALMPHELRFFGPLSNPLWHW
                     TKKRIVNTRWIPNAFKHAAQKEMLPLPKTSLQMMDADLNLITTPKLFLEEEQLPENYR
                     IVGPIFAKLSTSLPEEVLTFIQRKQQERKRIIYFAMGSSGNPRMLRKILFFLQKQPDL
                     AVIAPIDYLLDDIQSDSEDLLITEYLSSHLLHEFIDFSFIHGGEGTVQTACESGKPFI
                     GVGMQFEQSCNIDYCVKYGNAIALTKPVTERKLQIALREVSSPKIRQQARTLQAVFPI
                     NGPQQAIQEIETFLSNHPI"
     gene            complement(12193..12453)
                     /locus_tag="ACG8LA_002077"
     CDS             complement(12193..12453)
                     /locus_tag="ACG8LA_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HFQ0204368.1"
                     /translation="MYWLILFFVFIFLLTASHLILNMLATYHIQINRWIWALASFLIV
                     ILPKIIVPHMNVLFSWGTYVLCGIFAINFMIEQHRWFVTSKL"
     gene            complement(12480..13781)
                     /locus_tag="ACG8LA_002078"
     CDS             complement(12480..13781)
                     /locus_tag="ACG8LA_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFQ0204369.1"
                     /translation="MEKLMKWVEEKLVPPMAKIGTQRHLLAIRNGVVSTLSLILIGTF
                     FMVFINLPFPGWNEFIAPYSATIVLPFRMTMGLMAIYATFVMGSDLAKSYGLDSVTGG
                     ILSLGTFFMLQVPVNVLTPEEAPLGWVLPMSSLGASGMFAGILSMIFAVEVYRFFKNR
                     NITIKMPEQVPPAVARSFEALIPGAVILTITWLIRSVAGFDVNAALLSLFEPLTNILG
                     NNLLGVLLPMFLIHLLWSFGIHGMSIVGAVVRPMWLIMLDENAKALADGTAATQLPYI
                     APEQFYQWTVTIGGAGATIVVSVLFIFFCKSKFLKEVGRFSIIPGIFNINEPIIFGAP
                     MMLNPYMFIPFNLVPLVLTIISYFAVKLEMVNRFTVLPTWTLPAPIGGYLSAGNDWRV
                     VILIMINTLIAFIIYYPFVKAYDKKMLSDEQSRGENEVQTV"
     gene            complement(14073..14531)
                     /locus_tag="ACG8LA_002079"
     CDS             complement(14073..14531)
                     /locus_tag="ACG8LA_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HFQ0204370.1"
                     /translation="MHFFKTRNILKAVASGQIIPLTAVKDEVFSSKMIGVGYAITNHD
                     GYIHAPVKGIIDNIFPTRHAITIESESGRKILIHMGLDTVELEGSPFQIRVESNQEVK
                     EGTLLAIIDLKKLEQAQKDTVIIVVSPGIFEGNLLKQNQEVKIKDSCFEF"
     gene            complement(14544..15875)
                     /locus_tag="ACG8LA_002080"
     CDS             complement(14544..15875)
                     /locus_tag="ACG8LA_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose-6'-phosphate glucosidase"
                     /protein_id="HFQ0204371.1"
                     /translation="MMMKKQIITIAGGGSTYTPGIVQAILNNEKRLPLSEIRLYDIDE
                     ERNMDMYLIVKFMLKRKGFSNIRIRATDDPKLAFTGCDFVFSQIRVGGLEMREKDEKI
                     PLKHGLVGQETCGLGGFAYGMRSIKGLLEIVDHIQDYAPKAWILNYTNPESIVSEAVR
                     RKYPNVKMINACDMTISIEETIAVNYGYDRKNWIVTYYGLNHFGWYTSIYDKELQREI
                     MPEIIEKLITKEMQVADFNIGDKTWQKTFQMMSVITKNFPSNIPNNYLEYYLYPDMVV
                     EHTDKEYTRANMVMDGREKNTKEMADKIRRGIVEEVLNFNFGEHGQYIVDIAISLLND
                     DRRRFMLIVPNQGAIPNLRSDAVVEIPAYVGATGVEPITLRKPISDFHKGLMEAQVAV
                     EKLLVDAYFEGSYQKALQAFTLNQTVPNARVAKKILDEMIKVNKKYWPALK"
     gene            complement(15886..17328)
                     /locus_tag="ACG8LA_002081"
     CDS             complement(15886..17328)
                     /locus_tag="ACG8LA_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFQ0204372.1"
                     /translation="MRIFNRGGIKMNVKSNVQKLGRAMLLPVAAMPLAGLIMRLSADD
                     MLNIPVIGAAGNAVFGNLDILFAIGVAIGFVKNKDKGIPALTGFLAIATLKKGLEIMD
                     PEVNMGIFGGIISGLVAAWTYNRFKEQKLPVVFSYFAGEKFPLTMVMILQTIAAVFLG
                     FIWPLIQIGIDNFAKLLVDMGALGVGIFMFLNRLLIPFGLHHVLNTYIYYDLGSYTSP
                     SKEVFRGEMTRFINGDPQAGLFLSVFFVVMMFGIPAICLAIYKAAYKENKEMVKGIMG
                     SGAGTSFIANITEPVEFSFMFLSPMLYVIHALFAGLAGIVCYLFNIRIGFTFGACIVD
                     YLINFRIATNAILILPIGIFFFALYYVTFYYLINKRNIQTLGREAKAEFGNEVTLEET
                     ELGLASKNYEYMATKMLQAFGGKANILDVYSCNTRLRVEVVDPTMVEEQRIKQLGISG
                     IIKPTEKNYQIIIGLEVTYVMAEFNKLLEE"
     gene            complement(17315..18079)
                     /locus_tag="ACG8LA_002082"
     CDS             complement(17315..18079)
                     /locus_tag="ACG8LA_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate deacetylase"
                     /protein_id="HFQ0204373.1"
                     /translation="MGKVIFNSDDFGYSHGVNYGIMDAYQRGILTSTTLMANMPGFEH
                     AVKLRKEMPRLGVGVHLTLTCGKPLLKTVDTLIESGEFRSLSYYQHPFNIDKDQLYQE
                     WNAQIQKIYHAGIIPTHLDSHHHTHTLDENQEVVVTLAKKYDLPVRSNFERKDEVRHV
                     DYFEPCFDVVGETDEKKRQINTSVEEYLASLLMILREDKTIEVMCHAAYLDQELLNGS
                     SFVYPRTHQVEFLIHSAFAQKVKNDPLIELVTYEDI"
     gene            complement(18183..19058)
                     /locus_tag="ACG8LA_002083"
     CDS             complement(18183..19058)
                     /locus_tag="ACG8LA_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HFQ0204374.1"
                     /translation="MKESASCFVLSYRGGELTVYVMKKLNHNAVLIDDDGIEKIAMGK
                     GIGFSAKVSKPFDVEDADKLFVLDSKEKIKRFSEIVSQIPIEFMDFAEEVIELITARI
                     SSPLDSNIYITLTDHIYFAIQRKREDRDVTAIMLPEMRFLYPNEYDIAVEVVERINHR
                     YQTELGSNEVGFITMHIINAELGEPNSLKSLKIVEMTTTILSHLEKSYSNVYDKESLT
                     YHRLMVHIKFLVKRLIYQEETPVENIGFFTETFKHSKAYCTALKIKDIIEQQFQLAIQ
                     ENEIIYLAIHLARIY"
     gene            complement(19313..19397)
                     /locus_tag="ACG8LA_002084"
     tRNA            complement(19313..19397)
                     /locus_tag="ACG8LA_002084"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19361..19363),aa:Leu,seq:caa)
     gene            complement(19415..19486)
                     /locus_tag="ACG8LA_002085"
     tRNA            complement(19415..19486)
                     /locus_tag="ACG8LA_002085"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19452..19454),aa:Gln,seq:ttg)
     gene            complement(19496..19568)
                     /locus_tag="ACG8LA_002086"
     tRNA            complement(19496..19568)
                     /locus_tag="ACG8LA_002086"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19533..19535),aa:His,seq:gtg)
     gene            complement(19630..19714)
                     /locus_tag="ACG8LA_002087"
     tRNA            complement(19630..19714)
                     /locus_tag="ACG8LA_002087"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19678..19680),aa:Leu,seq:caa)
     gene            complement(19735..19805)
                     /locus_tag="ACG8LA_002088"
     tRNA            complement(19735..19805)
                     /locus_tag="ACG8LA_002088"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19771..19773),aa:Cys,seq:gca)
BASE COUNT         6306 a         4097 c         3083 g         6361 t
ORIGIN      
        1 taagaacaat agccttttat tatatatatt attcaaatta gttatatcga gtgaaaaaaa
       61 ctttcaaatt gattcttttt atttatcata aagatataga tacataatca ttttcactta
      121 catatatttg aatattaact aaaaacagca agaaagaaga ggatcaaatg tattatgtag
      181 aagtaaaaac aaaaggcgtc aaaaacaaac aatatgtgaa aggtatcagt aacgaatatc
      241 ctttacttgg ttcatggaaa gaagctgctc ctttttccaa accatgtgcc ataaaaataa
      301 agaacgagct agaaaaagaa ctgacttgtg gtaaagctgt tgtagatatc atcgaaaagt
      361 aaatccaatg tatagaaagg aagatcacac atgaaaagcg acgtacaaat tgctaagatt
      421 atagaattag aagaagaaga cgcagtgttg acaattgaaa aaaaataaat gtttgtatac
      481 catatgatta tttcaatatg tatcctggaa ttggagatct cgtagagcta tatcaagatg
      541 aatcaaatat acttgtcatt catcatgaaa tatagagact tataaaattg tttattttta
      601 taatgtatca gtatagaaag gaaataaaac atggattata ctgttgaatt tgacagtgaa
      661 ctacttaagc aatttccaca agaagaacat ttcatgtata aagaagcaat ttcccacaaa
      721 gtgacagagt atttggagca taattttttt cgtataaagc cagtgcgtac tcgttcggca
      781 aaaggaatat acgagatgaa agtcaaaatt aataaaaaaa attatcgcat agcatttgct
      841 ttaaaaaaaa atcatgtgtt cattttttat attagttcga atttgcaaaa aattgtattt
      901 gataaagagg tgagtaaaaa aataaaatag ctgagcattg gaggatagat tgagtgatac
      961 taagtctatc ctcttgtttt tctaaagaac taagctagaa ttttttcttt tgtacgttat
     1021 tatatgttat ttgtcattac caaaaagcac cttttttctt ctagtatcta tgacataaga
     1081 aataccaccc atttccttta cttgaacaaa tcctactgat tcataaaatt tttttgtttt
     1141 ctcagtatca tctgtcaata attcgatttg gactggtcca taactagtga tcttctccaa
     1201 agcttcattc aaaagcactt tgcctattcc ttggcgctga tacctcggat gaatgaggat
     1261 atcttgaata aatgcgatcg tcgcaaaatc agtgatccaa cgaacgattc cgataatctt
     1321 cccttcccca ttacgcttta tcagagattc agattgttca aatgctctag ctaaccttgc
     1381 agtgtctttt gtgtaattcg tccaaccaac gctcttatat aattcagaaa tctcatcgat
     1441 cataagggaa tcaatattca tttttttctt cctttcttat acaattctcc ctctaataat
     1501 acagttcttt gactatttaa tctatcacat ataactctcc tgtaaagatt ctctcgattc
     1561 cttaaaattc ctctttcctt ttagaatgca tactttttga taaataaaaa ggttgtgata
     1621 aattttcttc acaacctctg tttctctcta tcaagtgtta tcttttaatt ttctaccctt
     1681 accctagcat ctctattgcc cgtagtatgc atactttcca tgtttgcgaa aataatgttt
     1741 atctagtaaa tattgcggga tttcacatat attggggttg atcagctcgt tttctttggc
     1801 catcagacaa atttcatcta agatcaaact gttttctact gctttcatag gtgaatcccc
     1861 ccatgtgaac ggtccatgtc catagacaag tactccaggg acttcgtttg gatctaattt
     1921 tctttcctta aacgtctcga caatcacatt ccctgtatga acttcgtaag cttctcttac
     1981 ttcttctttc gttaattggc gtgtacaagg aaccttacca taaaaagcat cagcatgagt
     2041 cgtgccataa gctggcaaat cgcgtcctgc ttgcgcccac atgacggagt gcgtggaatg
     2101 agtatgagta atagcagtta tatcttcaaa agtttgatac aaaacaacat gtgtggggag
     2161 atctgaagat ggttttaagc tatcttcttc tattatattt cccgacaaat ctgttaccac
     2221 catttgatct gcttgcatgc attcatatct gacaccgctt ggcttaatga cgatgactcc
     2281 tagctcacgg tccacttcac tcacattgcc ccaagtcaat ttgactaatc cgtatcgcgg
     2341 caatgccaga tttgcttcaa ggacacgttg cttcattgct gcaatttttt cttcacaaga
     2401 catcatagcc agcctccttc aatttagaac ttaagtagtc ttttgcctgc tggatttctc
     2461 ttcgaaagtc ttggcttttt tcactccaca tttcaatcag aaatgttcca tcataatcta
     2521 gacgtttcaa atgtcttaat aatccaagaa aatcaacaca accgctacca aaaggaacat
     2581 cacgaaactg gcctgaatat tcttttgtta cagggtaagt atcttttaag tggatagcag
     2641 tgatataatc gatccctttc tcaagttctc gagccggatt attttccggc catgcggaca
     2701 aattgcctag gtctggatat acttgtagaa aaggtgaatg aatctgttct ttgatttcta
     2761 aaaattttga aatggagttc ataaatggat catccatgat ttccacggaa agaatgatgc
     2821 catatttaga agcttccttt acgctttctt ttattccttc gataaagtct tctctggaat
     2881 tcattgattt ctcttcataa taaacatcgt atccagctat ttggattact ttgacgctta
     2941 gattatgcgc caaatggatt gcttttttca ttagttgttt cgctgctttt ttcttttctg
     3001 gatcagcaga accaaacgga aatcgccgat gcgcacttaa acaaatcgaa tggatacgta
     3061 caccggagct gaacatctct tctctcagct cagctatctt ttcttcagac caatctaatc
     3121 gtgctaaccg ctcatccgtc tcatcaatcg acatctcgat aaaatcgaag tccatttctt
     3181 ttacaaggga aaaacgttct ttccatgaaa tatctttggg taacgctttt tcataaatcc
     3241 caatttgagc catttcctta cccccagata cgaatgatct catctttgaa gttttgtgcg
     3301 gccttcatcg gatcatttgc tgctgtaata ccacgaccag tgataaaggt atacacatcg
     3361 atcccttcaa ataagtgtaa tgtgtgtgga tttaatccac cagttacaga aacattaaag
     3421 cctagttcaa tcagtttttt gatcttcgat aaatcttttt caccccaagt ttcaccagat
     3481 aacagcgcat cacggctttg atggtagatt acctgccgga taccgatgtt atgccaatcc
     3541 atggcttgtt caaaagtcca attgccgtag agttctactt gcaattcacc tatttctttt
     3601 tgtgctgcct ccatagttgg aatcgttgca caacaaatga ctgtcatcca gtctgctcct
     3661 gcttttgcaa cattactcgc cactgttcct ccagcgtctg cacatttcgt atcagcgact
     3721 agttttttat ctgggaacat actgcgaata cagcgaatcg ctttttgtcc ttcctgtaag
     3781 caaagaattg tgcccacttc aataatatct actacatcac caactttcat aacatctcct
     3841 aatgcatgtt ctaagtcatt gtgatctaac gcaatttgca aattcggcct gctcatctta
     3901 gttccttcct ttacttgttt ttttggtacc actttgtttc agcaaatttt tcactgattt
     3961 ctttgactga catcacattt ttgataccga taactgtaac tccttttttc tctgcctgag
     4021 taaacatatt caaaaaattg actggcgtaa aaactacatc gtattggcca gctgaacttt
     4081 ttccctctga aatggcacaa tgatggattt tggtaattgg tacgtttagt tctttcattg
     4141 ctttttccac acttctcatc atcatcaagc ttgttcctga tccatttgca cacgatacta
     4201 aaattctcat cttaatccct ccattatgag tgttgtctaa tcagattttc ttttatactc
     4261 tctgcttttc tgcatatgtg tcatagtctt ctacaatcaa aaaataacca tcaggatttt
     4321 tccgatattg taactgcgga atagccaata aaccaatgac aactacggca attccagcat
     4381 aacctaggac tttcatgatt actgtaaaca atggccaagc tgttgcccag tcgaacatcc
     4441 cgatataacc accgtatgtt gacatcccaa tccatgtagc gaataatgct gaaccgccta
     4501 cttgtatgat tcctgaaaga aacgggaaca ggcaagcggc tttgaatcca cctcggttat
     4561 tggcataaac tgctataacg gcattatcaa agaacaacgg aatgaaaccg gctatgacga
     4621 tcgttggtga tttcaataaa atcagtaaac caatcatcaa aaactgtccc aaagcaccaa
     4681 acaagaaccc aatcgttacc gcatttggcg aaccaaagcc aaaagtagca gctacgtcaa
     4741 ttcctggaac agctcctggt aaaatcgtgt ttgagattcc ttggaaagat tgagttagtt
     4801 catcgacgaa tgtccgaaca cctaattgca agatcgccag atataccgca aaatttaaag
     4861 aagtcgtcat aatgtagaat aagaaactct gcccttcttg catgaattgc gcttgaatca
     4921 aataatcttt gcctagtaca atcagaatga tcccaaagaa aaatagcatg agtaacgaag
     4981 tagcaaccat attctcattg aaaatcgaca agaatcctgg taatttgata tcttcaattt
     5041 ttttgtcttg cttgattgat ctatttttct tttcatcccg ctttttcatc cactcagcta
     5101 attttgcaaa tataaagatt ccgaacattt gctgatgtgc cactgcaaat ccggcacctt
     5161 ctgtcaattc ctgcgtgatt cctactgtta agttagaagc tactgtccaa taacaaccta
     5221 aaatcagtcc cataaaaatc aatgcttgta tcctacctag atcaggaaag caaaacagta
     5281 aaatccaaaa agcggtagct gcttgttgaa cctgaacgtt tccggtagtg aaaacggaac
     5341 gcagtttcgt atatttctga aaacggacta ataagatatt taaaacaaat gcaatcagta
     5401 ataaaatcat cacatctcca aaggtacggc caaatgtctc cattaatcca gcatccacag
     5461 cattttgtcc aaaataagga tctgtaacca tggcatccaa attgaaccgt tcctttagtc
     5521 caaccaagat tggccgaaaa ttattgacca aaccaccaga gccaacagtc aaaataaagt
     5581 aaccgaccgt tgcctttaag aatccagcga tgcattcatg aagcgggcgt ttcagcaaaa
     5641 tatagcctaa taacacgata aaaccaatca ggtatgctgg ctgcgtcaag atatttgttg
     5701 caaaatacgt ccaaatgctt aacaaaaatt cccccatctt ttttctcctc tatcaattaa
     5761 ttatattctg ccatcacaac ttggtaatca tcgatggagt tcgtagagat gagacgctca
     5821 accaatccat ctgtcattaa taattcggat aatttttgga tattttctag atgttcttct
     5881 ggatcttttg ctgcgagtgt aaaaaacaaa ctagccgttt tctcctcatt ctccccttca
     5941 ctttcaaaac ggattggctg tttcaacttg gtaaatgaaa tagctgttcc aaaaacacca
     6001 tcactttttt ctgaagaatg cggcattgct acttgaggtg cgatcacaat ataaggaccg
     6061 tatttttcta cacaatggat gatctcctcc acatacgttt catcaataat ttccttatcg
     6121 atcaatacaa gacagctttc ggcgatagct tcacgccaat ccgtgatttc tttatctggg
     6181 taatgaatca attgatggtc aaaaaagtat ttcagcaaga aactcccctt ctttcttata
     6241 aaaacgacgg aaacggtgta tcattttcaa tcgagaagac atcttcaaat cctcgataaa
     6301 aattaaactc aagatcatct ttgtttgtcg gatagatgaa tttcccgcct acttgccaga
     6361 tataaggttt aaatccatac ttcaggcgat cctttttgaa tttccaaatt tcagtgatct
     6421 cttttggatc agccataaaa ttagaccaaa tatcgtagtg gacaggaatc actacttttg
     6481 cattcaatga ctccgccatg cgcagcatat caacagaagt aactttgtct gttatccctc
     6541 gtgggttttc accataggcc cctaaacaga catcgatttt gtgttcatta ccatgtttgg
     6601 caaataaatt ggagtaatgt gaatctcctg catgataaag attccctcct gatgtttcga
     6661 ataaatagtt tactgcaatt tgatccatct cctgaggcat ttttcctttt aatacctctt
     6721 ctggatcttc acaagtgacc aacgctgtcc gatcaaacgc ttctaaagct actacattga
     6781 tgtctttgat tttgactgca tcacctggct ttactgtaat cgttttttct tcaggaattc
     6841 cccatttttg ccacgtgcga accacttctt ttggcccaat gaatgttgct tcaggacaat
     6901 tttgatgaac tgctgcggct gtatggatat ctagatgatc ggaatggata tgtgtaacga
     6961 ttaaagcgtc tacatttttt atcgcaaaag gatcgattac gaaaggctga gtacgtaaat
     7021 taggctgcat attttgaacg ccactcatac gcatcatctg atggcctttt ttcatcatgc
     7081 cattcccatg actacgtttt cccgtcccac accatagatc acataaaata ttcgttcctt
     7141 catgactttt cagccaaatt cccgtacagc ccagccacca catagcaaaa gttccaggat
     7201 ccactacttc tgtttcgatt tcttcattca agtatgtgcc ccactcagga aatgtttcta
     7261 ctaaccactt ttcttttgtt acttcattga cagttttact catttgcttg ctccccccat
     7321 atcgttgttc caacttacaa gtaaatatta atgtgtatca gcatccatga aaaccctttt
     7381 atatgaccgt ttgtttttta tatgattttc tttcagtaat caatgattgt ttcagtataa
     7441 taaagacaga tatgaatgtt taaatgaaca actagtcaaa taaatccatg gatcaagatg
     7501 tccctcagga ggcaaaagtc atgaaaaact cacttgtcaa tattgaaaaa cgtcaaaaag
     7561 aaattttgga actgcttcag cagactgaac aactatcaac tttcgaatta gctgaatccc
     7621 ttgatgtatc tattagtacg atacgaagag atttaaattt attagaagaa aaaaacgaga
     7681 tcatacgcaa ttacggttat tgttcttata attacaaaaa ccagactgat tttgatcaat
     7741 ctggtcctga aaggattaaa caagcgattg ccagagaagc tagtaaatac attaacgatt
     7801 atgatacgct gtttatcaat tctagctcga ctgcgttgaa aacactggat tttcttcaat
     7861 ctaaccattt gacagtcatt acaaacaacg tgaaaatcaa ttactctccg cacaaagata
     7921 attgtagtta tattttaact ggtggagaga tgcgctttcc aaaagaagca ctagtgggcg
     7981 acatcgcatt aaatacgatt tcttcagtca atgcagacat ttgtatcatt ggctgtagcg
     8041 gagtcgatgt agtacatggg gtcacaacaa agatattaaa tgaatcaacg atcaacgaaa
     8101 tgatggtcaa caagacaatc aaatgtaaga ttttagtcgc tgatcatcga aaaatcggac
     8161 tgacatcaaa gttcaagatt gctgatattt cagtctttga ttatttgatc actgataaat
     8221 tttgttctga aaaagtatta gaggagatca gaaatacggg gataaaaacc attcaagtag
     8281 attcatttta agaaccagga cgtaaatatg taaataggat tatcaaaaaa atgaataaca
     8341 aatttatcga taaatgaaaa acacgctacg ctcaaattga taaaggaatc ccaagatgta
     8401 tccatccaat cgataccatc ataatctatt gcttctttta taaccgttat atgttgccta
     8461 aataggaatc aaacaatatc gaaaaaagga ggtatgacaa aagtcacacc tccttttttc
     8521 gaataaacgg tattcaaatc agaacactga tttcacaacc actttatttc aggtcgtttt
     8581 caatcacctt taccgcgtaa tcatttccgt tgaaacgcgc tatttttttt gcgtccatat
     8641 atctttctaa ataatcatct tctcctaatt gcttatggca agaagcaatt tcataaagca
     8701 agtattccaa tgcataagtc gatttatgtt tcttattata ctcaataccc ttctcacata
     8761 attggattgc tttatcataa tcctcgattt tacggtaata ggtggcgata tcataatata
     8821 caatgcagac catcagatta tcaaaatcag tctcactcaa tattttaagt gtacgctcca
     8881 cataaacttt cgcaaaatct aattctcctt ttgacaagta gatcattgcc acgtttgcag
     8941 ctgcttgtaa gtgatggata tctgtttcgg tcgtttgttc caacacttga ttaaaataaa
     9001 ataatgctgc atctggtttt ttcgcataaa gatgatcaag cagtccttga taaaataaaa
     9061 tttgatttaa aagatcagaa ttacttactt tttcctgatc gatcgtttgt aaaattttat
     9121 aagattcttg gtattttgat acagaattca atgattgaat ctcatttatt tttttcctga
     9181 ttttgtcttc ttctgtttct actaatatat cggagatctc gacattcagc tttttgcaaa
     9241 gcgcacttaa gatattgatg cctggcgaca tattcttgtt ttcgatattg ctgacagttg
     9301 cttgttcaca aatgccttct gctaattgta cttgtgttaa cccctttttc tttcggtatt
     9361 cttttagtaa tgctccatct actttaatca aaacaatttc cttcccttta aaaaattatt
     9421 tctcctttat atcatacaca aaaaaaagtt ctaaacaacc aaaaatgttt agaacagaat
     9481 aaaaatttta attttaaaat aatattcaaa ttaaacaact ggcgtatctg ctccttgatt
     9541 tctttttgtg ttatctgaat aattatcgtt tacagttata acacatagtg aaaattgtca
     9601 tggcgagaaa gtctaagaat atttttaaac ataactattt ctttcttacg tgtgtataat
     9661 gacgacagca cacctatcaa ttaatataat tattttattt ttttatgttc tcatgtttat
     9721 ttttaatgac acaacttctc gtatttatct ggcacaacat ataaatcgat caaaaaattg
     9781 ttgcgtgttt ttttgaaaat tggagtttca acttgattac aaaatttaaa tttagaagtt
     9841 gtgaaaacag cgagagacag tttaatattc aaaatataca taggctactc gaacgctgtg
     9901 ttttttagta tactagtaag aaacgaaggg atagactcat tccaataagg aggatttcat
     9961 gaagacaatt ctttttgctc ctgcagtatt caatttagct gagacaacac gaatgattga
    10021 ggttgccaaa gctatgaaag accgttatta ctgtgtattc tttggctttt ctaaaacttt
    10081 tgctcctttg atcacagaaa gtggctttga gtatcattta ctagcgccga tccttacgaa
    10141 aaaacaagaa gaacaaatca taaaatttga ccagttgcgt acacttaaaa acccttttac
    10201 caaagaaatg gttgcctctc gtatcactag tgaacagagt ctgattgcta agtttgagcc
    10261 tcgactgatt gtgacaggtt cgaatgtgac aattttttta tcggcccgca ataaaaagat
    10321 tcctttagta tatgttaaac cctatgcttt gagtgaacct ttttttcaat cagagcatgc
    10381 gctgatgccc cacgagttac gtttcttcgg ccctttaagc aatccccttt ggcactggac
    10441 aaaaaagcgt atagtaaata cccgatggat ccccaatgcc ttcaaacacg ctgcacaaaa
    10501 agaaatgctt cctttaccaa aaacaagttt acaaatgatg gatgctgatc taaatctcat
    10561 cacaacgcct aaactatttt tggaagaaga acagctgccg gaaaattatc gaatcgttgg
    10621 tccaattttt gctaagctca gtacttcctt gcctgaagaa gtgctaactt ttatacagcg
    10681 aaagcaacaa gaaagaaaac gtattatcta tttcgcaatg ggtagttcag gcaatccgcg
    10741 tatgttacgc aaaattttgt tcttcttaca aaaacaaccg gatctagcgg ttattgcacc
    10801 tattgactat ctgcttgatg acattcaatc tgactcagaa gatcttttaa taacagaata
    10861 tctgtctagt catcttttgc atgaattcat tgatttttct tttatccacg gcggggaagg
    10921 gaccgtccaa actgcctgtg aatccggcaa accgtttatc ggtgtgggga tgcaatttga
    10981 gcaaagctgt aatattgact attgtgtaaa atacggaaac gcaatcgccc tcacaaaacc
    11041 agtgactgaa agaaaactgc agattgctct gcgcgaagtt tcttcaccca agattcgtca
    11101 gcaggcacgc acgctgcaag ccgtttttcc aataaatggt ccacaacaag caattcaaga
    11161 aatcgaaacc ttcctgagca accacccaat atagtttcaa gtagaaaaag cttttttaat
    11221 agagactcat cagtaatttc gctattcgag acccagacag tgaaaataca aaaaaagtaa
    11281 atagtggatt gaaaagttag agttacttaa attacggtgt ctaaaaaaca caaaatcatc
    11341 cttaaaataa aagatctgac gctatccaaa tgagcatagg tagcgtctgc catttattct
    11401 tagtcaaatt ctttgacacc tttctctggt tggatcatct caacgtttct tcaaaagaaa
    11461 gaccataata attaggcaaa tacattttct taaaatgtgt catatagatc tagaagcatc
    11521 gctttgtaga gatttgtgcc gctagtcccc tcaacaatta ctaaatcaaa tgtaggattt
    11581 accactttat ctttgataat caacctccct cttctgttga gacaatgatc tcgcaatccg
    11641 atgcatactc ctatataaac tgccagcaat ccccacatat tgagtagatc atgtcagaat
    11701 gttctatgtc gtcagcaacg atacactaaa agtcacgttc accatgactg attgctattc
    11761 ccagcacaat tatttctata cacgtttcat gatttgaata aacactcaca tcatacatat
    11821 taccattcat acaccatact gcagccccta ctatatggtt gtaagctccc aaatctatat
    11881 ttgacttgat cactttggta gtagatctac taattctaaa tccattgctg ataaaatttc
    11941 cattttttcc tccttctttc tgccaaaaca gttaaaacaa taataatctt tatgtaaaaa
    12001 agggctgtga caaaagcctt gtcacagtcc catattccga ataaacggtg gtcaaaagct
    12061 tgcatctgcg gtaataagtt caaccaaacg aaaaataagc caacatttca caaaaattta
    12121 agaagcaatt ttcgtaaatt tcttcttatt tcttgaagct aaccacttct gttacaacca
    12181 cttttagaac atttaaagct tcgatgtgac aaaccatcta tgctgctcga tcataaaatt
    12241 gatagcaaaa attccacaaa gtacatatgt cccccatgaa aacaaaacat tcatatgcgg
    12301 tacaatgatc tttggaagaa tcacgatcaa aaatgatgcc agtgcccaaa tccatcgatt
    12361 gatttgaata tgatatgtag ctagcatatt caatataagg tgactagccg ttaataaaaa
    12421 gataaaaaca aaaaataaaa tcagccaata cattgtttcc caccttctaa aaaccaaact
    12481 tagacagtct ggacttcgtt ttctccacga ctttgttcat ctgacagcat ctttttatca
    12541 taagctttta caaatggata atagataata aatgctatca atgtgttgat catgatcaag
    12601 ataacaacac gccagtcatt tcctgctgaa agataaccgc cgattggagc tggtaatgtc
    12661 catgttggca aaacagtaaa tctattgacc atttctaatt tgactgcaaa ataactgata
    12721 atagtcaaaa ctaaaggaac taagttgaac gggatgaaca tgtaaggatt caacatcata
    12781 ggagctccaa aaattatggg ctcattgata ttgaagatac caggaataat agaaaaacga
    12841 ccaacctctt tcaagaattt tgatttacag aagaatataa acaaaacaga taccacgatc
    12901 gttgctcctg caccaccaat tgttaccgtc cattgataaa actgttcagg agcgatatag
    12961 ggtaattggg tggcagctgt accatctgcc aatgcctttg cattctcatc caacatgatc
    13021 agccacattg gacgaacaac agcccctaca atactcatgc catggatacc aaatgaccac
    13081 aacaaatgga tcaaaaacat tggtagtaaa acaccaagca aattattccc taaaatattg
    13141 gttaaaggct cgaataacga taataaggca gcgtttacat caaagcccgc gacgcttcga
    13201 atcagccaag taattgttaa aatgactgca cctggaatca atgcctcaaa actacgggca
    13261 acagcaggtg gcacttgttc tggcattttg atagtaatat ttcgattttt aaagaaacga
    13321 tatacttcca ctgcaaaaat catagataag atccccgcaa acatcccaga tgctcccaaa
    13381 gaactcatag gtaagaccca gccaagaggt gcctcttcag gagttaaaac gtttacagga
    13441 acttgtaaca taaagaacgt tcctaaagat aatataccac ctgtcacact atctaatcca
    13501 tatgatttag ctagatccga acccataaca aaagttgcat aaatagccat caatcccatc
    13561 gtcatcctaa agggtaaaac aatcgttgcc gaataagggg caataaattc attccatcca
    13621 ggaaacggta aattgataaa gaccataaaa aatgtcccaa tcaaaatcaa tgacaatgtt
    13681 gaaacaaccc cattacgaat tgctaataaa tgacgctgtg taccaatttt tgccattggt
    13741 gggacaagtt tctcttcgac ccatttcatc agcttttcca ctaaaaccac tccttttcaa
    13801 taaaatatga accattcatt gcatgacaac gcaaagaatg ttcataacta attatataat
    13861 taagaaattt tatttcaata tattctctta aataatcaaa tttattttta agaatcctga
    13921 aaataagttt tctaaatcat aggagcaaca aaaaaattcg ataattaaca aaaatcaaaa
    13981 tgattaaatc tagtgattga aacatatcat ttcaaaaaaa ttttgtaaat tcacccataa
    14041 atatcaccct atttaacttt tttcatcgta cactaaaatt caaaacaact atctttaatc
    14101 tttacttctt ggttttgttt taataaattt ccttcaaaaa tgcctggaga aactacaatg
    14161 atcaccgtat ctttttgtgc ttgctccaac ttcttcaaat ctataatagc taacagtgtc
    14221 ccttctttta cctcctggtt actttcaacc cgtatctgaa acggacttcc ttcgagttca
    14281 actgtatcta aacccatatg gatcagtatt tttctgccag attcactttc gatcgttatg
    14341 gcatgtcggg taggaaatat attatcgatt attcctttaa ctggcgcatg gatatatcca
    14401 tcatgattcg ttatagcgta tccaactcct atcatttttg aagaaaagac ctcgtctttt
    14461 actgctgtta atggaataat ttgaccacta gctacagctt ttagaatgtt tcttgtttta
    14521 aagaaatgca ctttttatca cctctacttt aatgctggcc aatatttttt gtttactttg
    14581 atcatttcat ctagtatttt ttttgcgact ctggcatttg gtacggtttg attcaatgta
    14641 aatgcttgta aagctttttg ataagaacct tcaaagtaag catctactag taacttctct
    14701 actgcaactt gtgcctccat caatccttta tgaaaatcac tgattggttt tcttagtgta
    14761 attggctcca caccagttgc accaacatat gccggtattt caacaactgc atctgaccgt
    14821 agattcggaa tcgccccttg attaggaacg attagcataa agcgacgacg atcatcattc
    14881 aacaaggaaa tagctatatc gacgatatat tgtccatgct ccccaaaatt aaagttcaat
    14941 acttcttcca caataccgcg gcgtatttta tcagccattt ctttggtatt tttctctcgt
    15001 ccatccatga ccatattagc acgtgtatac tctttgtcag tatgctcaac gaccatatca
    15061 ggatataagt aatactctaa gtaattattc gggatattac ttggaaaatt tttcgtgatg
    15121 actgacatca tttgaaaggt tttttgccaa gttttatctc ctatattaaa atcggcgact
    15181 tgcatttctt ttgttattag tttttcaata atctctggca taatttctcg ttgcaattct
    15241 ttatcataaa tcgatgtata ccagccaaag tggtttaaac cataatacgt aacgatccaa
    15301 ttcttacgat cataaccgta attcactgca atcgtttctt caattgaaat agtcatatca
    15361 caggcattaa tcatttttac attcggatat ttacgacgaa cagcttcaga aacgatcgac
    15421 tctggatttg tataattcaa aatccatgct ttgggggcat agtcttgtat atgatcgaca
    15481 atttccaata aacctttgat tgagcgcatc ccataagcaa atcctccgag tccacacgtt
    15541 tcttgtccta ctaatccatg tttaagtgga atcttttcgt ccttttctcg catctccaat
    15601 cctccaacac gaatttgtga gaaaacaaaa tcgcatcctg taaaagcaag ctttggatca
    15661 tccgttgcac gaatgcgaat atttgaaaaa ccttttcttt tcagcataaa tttaacaatc
    15721 aagtacatat ccatatttct ttcttcatca atatcatata aacgtatttc agataatggc
    15781 aaccgttttt cattgttcaa aatggcttga acgattcctg gtgtatacgt actcccgcct
    15841 ccagctatag tgataatctg ttttttcatc atcatctttt cctttctatt cttctaataa
    15901 tttattgaat tctgccataa cataagtcac ttctaagccg atgataattt gataattttt
    15961 ttcagttggt ttaatgatcc cgcttatccc taattgcttg attcgctgtt cctcgaccat
    16021 ggtgggatcc actacctcta cccgtaggcg tgtattacaa ctatagacat ccaggatatt
    16081 ggcttttcct ccaaacgctt gtagcatttt tgttgccata tattcataat ttttacttgc
    16141 taaccctaac tctgtttctt ctaaggttac ttcattgcca aactctgcct tagcttcacg
    16201 tcctaatgtc tgaatgtttc tcttattgat caaataataa aaagtaacgt aatacaaggc
    16261 aaaaaagaaa attccgattg gaagaatcaa aatagcattg gtagcgattc gaaaattgat
    16321 gagataatca acaatacatg ctccgaatgt aaaaccaatt cgtatattga ataagtaaca
    16381 gacaatccct gctaaaccgg caaaaagtgc atggatcacg tacaacatag gagaaagaaa
    16441 catgaaacta aattcaacag gctcagtgat atttgcaata aatgaagttc ctgcaccgct
    16501 tcccatgatt cctttgacca tctctttatt ttctttataa gctgctttat agatagctag
    16561 acatatagct ggtataccaa acatcattac tacaaaaaaa actgataaaa acagtccagc
    16621 ctgaggatct ccgttgataa agcgtgtcat ctctcctctg aaaacttcct tgctaggaga
    16681 tgtatagctt cctaaatcgt aataaatata cgtattcaac acatggtgca gtccaaaggg
    16741 gatcagcaaa cgattcaaaa acataaatat ccccacacct aatgctccca tatcaacgag
    16801 cagttttgca aaattatcaa tcccaatttg gatgagcggc cagataaagc ccaaaaaaac
    16861 agctgcgatt gtttgtagaa tcatcaccat agtcaatggg aatttttcgc ccgcaaaata
    16921 agaaaaaact actggtaatt tttgttcttt aaagcgatta tacgtccatg ccgctactaa
    16981 accggaaata attccaccaa aaatccccat attcacttct gggtccataa tttctaagcc
    17041 ttttttcaag gtagcaatcg ctaaaaaacc agtaagtgca ggtattcctt tgtccttatt
    17101 tttgacaaaa ccgattgcaa ctcctatagc aaataagata tccaagtttc caaaaacggc
    17161 atttccagct gcaccaatta ctgggatgtt cagcatatcg tcagctgata aacgcatgat
    17221 caatcccgct aatggcatcg ctgcaactgg aagtagcatc gctcttccaa gcttctgcac
    17281 atttgattta acattcattt ttattcctcc tctattaaat atcctcatat gttactaact
    17341 caatcaaagg atcatttttc actttttgag caaatgctga atgaattaaa aattcgactt
    17401 ggtgggtacg aggatacaca aaacttgaac catttaacaa ttcctgatcc aaatacgctg
    17461 cgtgacacat gacttcgatc gttttatctt ctctcaatat catgagtaaa cttgccaaat
    17521 attcttccac actcgtattg atttgtcgtt ttttttcatc agtttctcct acgacatcga
    17581 aacaaggctc aaaataatcg acatgacgaa cttcatcttt tcgttcaaag ttgctccgaa
    17641 ccggcaaatc atattttttt gctaatgtaa caactacctc ctgattttca tccaaagtat
    17701 gagtatgatg atgactgtct aaatgagttg gtatgatccc cgcatgataa attttttgaa
    17761 tctgagcatt ccattcctga tacagttgat ctttgtcaat gttaaatgga tgctgataat
    17821 aagataagga tctgaactct ccgctttcga taagagtatc gacagttttg aggagtggtt
    17881 tgccacacgt caatgttaaa tggactccta cacctagcct aggcatttcc tttcttagtt
    17941 tcacagcatg ctcgaaaccc ggcatatttg ccatcaatgt agttgatgtc aaaattcctc
    18001 gctgataagc atccataatc ccataattca caccatggct atagccaaaa tcatccgaat
    18061 taaaaatcac ttttcccatt tcattctcct tcttttttct actaaaatag gcgcaaccaa
    18121 ataatcatag tccatttact atgtgtcatt tggttgcgcc tatagatagt tacgccctta
    18181 ttttaataga ttcttgctag atgaattgcc aaatagatga tttcattttc ttgaatggca
    18241 agttgaaatt gctgttcgat gatatcttta atctttagtg ctgtacaata cgctttgcta
    18301 tgtttaaatg tttcagtaaa aaaaccaata ttttctactg gcgtttcttc ctgataaatc
    18361 aagcgtttaa ccaggaattt gatatgaacc attaagcgat gataagtcag tgattcttta
    18421 tcataaacgt ttgaatagga tttttctaga tgggacaaaa tcgtggtcgt catttctact
    18481 atttttaagc tctttaaact attaggctct cctagctcag cattaatgat atgcatagtg
    18541 atgaatccta cttcatttga ccctaactcg gtttgatatc gatgattgat tcgctcgacc
    18601 acttctactg ctatatcata ttcatttgga taaaggaatc tcatttctgg caacataatt
    18661 gctgtgacat ctctatcttc tctttttcgt tgaatagcaa aataaatatg atctgtcaat
    18721 gtaatataga tatttgaatc taatggagag gagatcctag ctgttatcag ttcaatcact
    18781 tcttccgcaa aatccataaa ttcgattgga atctgcgaga ctatctcact gaatcgtttg
    18841 atcttttctt tagaatctaa tacaaataat ttgtcagcat cctcaacatc aaatggctta
    18901 ctcactttag cagaaaagcc aatccctttc cccatcgcaa ttttttctat tccatcgtca
    18961 tcgatcaata cagcattatg attcagcttt ttcatcacat acaccgttaa ttcacctcct
    19021 ctatatgata aaacaaaaca acttgcagac tccttcatac atatttttgt ctccaaacaa
    19081 tttttaaaga caaaaaacga cctaagaaag aaccctttct taggtcgtgc ctaattgaat
    19141 agtagcaccc tacataattt acaaaaatag tttaacacat aataaaagcg ttatcaatat
    19201 cttttttact cgttttatga taatacttgt atcgaattga tttggaggta attacataaa
    19261 aacaaaaaaa atatagcaac tctctataag aaagttgcta tattgataat tataccggcg
    19321 gccggggtcg aaccggcacg tcctcaacgg acactggatt ttgagtccag cgcgtctgcc
    19381 aattccgcca cgccggcaaa tttaaaaata ataactgggg tagctggatt cgaaccaacg
    19441 catgagggag tcaaagtccc ttgccttacc gcttggctat accccaagaa taaagggcga
    19501 atgatgggaa tcgaacccac gaatgccgga gccacaatcc ggtgcgttaa ccacttcgcc
    19561 acattcgcca tcataaaaga tgttatttaa tttctcaata aaaaactaag atgaagacat
    19621 cttagtcaat accggcggcc ggggtcgaac cggcacgccc tcaacgggca ctggattttg
    19681 agtccagcgc gtctgccaat tccgccacgc cggcaagttg atttattagt actaaggcgg
    19741 taaccggatt tgaaccggtg atgaaggttt tgcagacctc tgccttacca cttggctata
    19801 ccgccattat actattatca atctataaaa taaagaataa attatag
//
LOCUS       DAZKKZ010000054        19598 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.055, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000054 DAZKKZ010000000
VERSION     DAZKKZ010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19598)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19598)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19598
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.055"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(474..773)
                     /locus_tag="ACG8LA_002089"
     CDS             complement(474..773)
                     /locus_tag="ACG8LA_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5960 family protein"
                     /protein_id="HFQ0204375.1"
                     /translation="MLFNETQLWFKFDPSNRFVKDFYKVWDSEVFFLAIEDSLLINLY
                     YSNKNYFKIPAAKTRMKKDVYFLFDIVTDVLDARSDHRRYDYIKYTFVDPERYKD"
     gene            complement(779..1009)
                     /locus_tag="ACG8LA_002090"
     CDS             complement(779..1009)
                     /locus_tag="ACG8LA_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204376.1"
                     /translation="MMEEFIRKNISDEYADFYDQSSKKDKFQMDVSILAILAFSENKQ
                     PVTAKKETVFSEGKIKTRYILEVETKFKNRSE"
     gene            complement(1445..2011)
                     /locus_tag="ACG8LA_002091"
     CDS             complement(1445..2011)
                     /locus_tag="ACG8LA_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFQ0204377.1"
                     /translation="MLQTALHFSHTLLQEILQPGDHVVDATMGNGHDTVFLAEHIGKT
                     GHVYSFDIQQQAIDATRERLEQRQLEERVSLFLQGHETLGEVIAEQQNLKAGIFNLGY
                     LPKSDKAIITMPETTRTAMEEILKRLVPRGRLILVVYYGHEGGEKELDMVDSFCSKLP
                     QETYNVLNYRFINQKNQPPILYCIEKKR"
     gene            complement(2011..2967)
                     /locus_tag="ACG8LA_002092"
     CDS             complement(2011..2967)
                     /locus_tag="ACG8LA_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390904.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HFQ0204378.1"
                     /translation="MTFPYSEGNKRYHSWNYALRNEFGGKIFKVPIDGGFDCPNRDGT
                     VAHGGCTFCSVSGSGDMIVAPEDPLPIQFQKEIDMMHQKWPHVQQYIVYFQNFTNTHA
                     PVEIIKERFEQVVNLPGVVGLSVGTRPDCLPDEVVDYLAELNERMYLWVELGLQTTFE
                     ETSKLINRAHDYQTYLDGVAKLRKHNIRVCTHLINGLPGESLEMMKENVRRTILDSDI
                     QGIKLHLMHLMRKTRMLRDYHEGRLQLMSRPDYVNVICDQLEMIPKEIIIHRLTGDAP
                     WDSLIGPMWSLKKWEVLNAIDEELLRRDSFQGKYDVRKKVSV"
     gene            complement(2967..3623)
                     /locus_tag="ACG8LA_002093"
     CDS             complement(2967..3623)
                     /locus_tag="ACG8LA_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HFQ0204379.1"
                     /translation="MKYKTSFQVAGSFFLVLFFILGWIVKFHLSWLSGFDQWFTGIVR
                     ASYPDLNSYQLFMTKFGNPLTVIILFACAALWMWYKKKRAETFWFVSGFIVIAGIINP
                     VIKLFFMRERPSLAHLVVETSYSFPSGHAAGSMILYGSLLFLLPAFVQKRTLRTLLQL
                     LMMFIIVSVGISRIYLGVHFPTDIIGGYLLSLSWLCLTYPVYREKRKQIDNSYRKKDF
                     "
     gene            3993..6011
                     /locus_tag="ACG8LA_002094"
     CDS             3993..6011
                     /locus_tag="ACG8LA_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HFQ0204380.1"
                     /translation="MENIARKERRRLEQTKRFRKAKRGAAIVGTAMVGCSVAAPLVQP
                     VPVQADETPVQFGARINTAAFITEIATYAQPIAQANDLYASVMIAQAVVESGWGSSAL
                     SQAPYYNLFGIKGSYQGQTVYMDTLEFLNNQWVNKKEPFRQYPSFAESFNDNAYVLRN
                     TSFGNGYYYAGTWKSNTKSYTDATACLTGRYATDPGYAGKLNNIIATYGLTQYDTPAS
                     GNAGGGATTGGNNTGSAGSTGGSSNSGNTNSGSATSTTYTVQSGDSVWGISNKFGITM
                     DQLIQWNNIQNNFIYPGQKLTIKGSQENGSSTNNSGNNTNSSGNAGTSNGGQTTGAKY
                     TVQSGDSVWKISNDHGITMAQLIEWNNIKNNFVYPGQQLIVSNGGSSNAGANTGSNTG
                     NTSGSSSSSSSSSNTASGTKYTVKAGDSVWSVSNKYGITMAQLIQWNNIQNNFIYPGQ
                     QLTVSNSGSTNSTSGNTGSSTNTNNSSSVNTGSSSSQGTYTVKAGESVWSVANKNGIT
                     MDQLIEWNNIKNNFIYPGQQLIVKGGTSANTNTGSTTSAAKPNTPNTSATTSTSSTGN
                     TMYTVKAGESVWSVANKHHITMDQLIEWNNIKNNFIYPGQQVIVKKGSSQSTNQQSVT
                     GSKTYTVKSGESVWSVADSHGITMAQLIEWNNIKNNFIYPGQTLIVAK"
     misc_binding    6081..6287
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            6438..8852
                     /gene="leuS"
                     /locus_tag="ACG8LA_002095"
     CDS             6438..8852
                     /gene="leuS"
                     /locus_tag="ACG8LA_002095"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004823 - leucine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006429 - leucyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HFQ0204381.1"
                     /translation="MSYNHKEIEKKWQKYWAKTNTFNTHDDPEKPKFYALDMFPYPSG
                     QGLHVGHPEGYTATDILSRVKRSQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTQK
                     NIETFRRQINSLGFSYDWNREVNTTDPEYYKWTQWIFTKLYEKGLAYEAEVAVNWVPE
                     LGTVISNEEVIDGKSERGGYDVVRKPMRQWMLKITAYADRLLDDLELVDWPESIKEMQ
                     RNWIGRSVGANIEFKVAGTDKSYTVFTTRPDTLFGATYSVLAPELDLVREITTPEQKA
                     AVEAYIEETAKKSDLKRTDLAKEKTGVFTGAYAINPVNGKEIPIWIADYVLSSYGTGA
                     IMAVPAHDERDFEFAQTFGLEILPVIEGGDVEKAAYTEDGTHINSEFLDGMNKQEAID
                     KMNEWLEENGVGKKEVSYRLRDWLFSRQRYWGEPIPIIHWEDGTVTAVPEEELPLRLP
                     KTKNIKPSGTGESPLANIEEWVNVVDPVTGKKGRRETNTMPQWAGSSWYYLRYIDPHN
                     KKELADYEKLKRWLPVDIYIGGAEHAVLHLLYARFWHKFLYDIGVVPTKEPFQKLYNQ
                     GMILGENNEKMSKSRGNVVNPDDVVETYGADTLRMYEMFMGPLDASIAWSENGLEGSR
                     KFLDRVWRLIVDENNKMRDRITTLNDGKLDKVYHQTVKKVTEDYENLHFNTAISQLMV
                     FINEAYKVDALPYEYIEGFVQLLAPIAPHMGEELWAILGNDGGISYAPWPTYDEAALV
                     EDEVEVVFQVNGKVRAKSNVPRDLGKDELEKAALANEIVQEYIEGKTVRKVIAVPNKL
                     VNIVAN"
     gene            9200..10753
                     /locus_tag="ACG8LA_002096"
     CDS             9200..10753
                     /locus_tag="ACG8LA_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WD40/YVTN/BNR-like repeat-containing protein"
                     /protein_id="HFQ0204382.1"
                     /translation="MDQELFIIEVLSAKQKIIEKAKKRAKRIMFKLLSLVFFSGLLFF
                     GAVSFLYRHMSAVVRSAEGMQKLNNLYHFSWGVGGITIVVLIVFLLLIWLRYHQLSRH
                     FDQWLSQRAQQFLHNKPTSQDDDYLYFEKTSTSQAFRIQKSDCQLLLRSLDDLPIYLG
                     ESKSKFGMNTFHIFLLENEPRWEKSQSSPGGYLTTKMSTLVTGFFLILLAGTIYYGRY
                     TQPKMSSHINAASHMTMNSTNDTHIQKTNEGLLADPKQKVNLTTQKINDLKLDTETHS
                     LYMTTDSGANWVFVPIDSQWLRFGEYTLTTGLIPEGYWMDNTYDISADFSWFIYSSGD
                     DVRLLTSRDNGKTWQTSIITQSVQPIRYRKAVFYGNDGLFICTSASGMSAETLYIYTT
                     MDGGITWIKSGSTMINQPVQNVSFVTTSLGFVSTRESLFYTNNGGRSFKESVLSIPEN
                     YQTGGIDLFQSPNEVTQISANTLETKFYLLKKGPIDAGKMFACLFRSTDNGETWQFVQ
                     QLSQVEQGD"
     gene            complement(11134..12918)
                     /locus_tag="ACG8LA_002097"
     CDS             complement(11134..12918)
                     /locus_tag="ACG8LA_002097"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0204383.1"
                     /translation="MEKKKTLNTRALIRFWKMIKPEHKYFYGLFLCSLFGNLLVVAMP
                     LIMGIGIDDLLSEIRKTGIGQLSFSDIKQALLFPVLLLIGCSVLSSITSFIQERTMAA
                     LSEKITLRVRKEITKKFKTLPMSFFDNHQVGDIISRTTTGLNQLSQVLLTGINQFFTS
                     VVTIAAAGLMLFYIESKLTLLVLLLIVGSSIVTTKIANKNKQISEQNQYELGVLNNRM
                     EEILAGNLVVKTFNQQAHAEAAIHEVNKKQYNAFKRAQFMNCAIYPAIRFINQLAFII
                     SAVFGAMLVLSGGVTIGFLQAYLQYINQISEPISTASYVINSIQSAMAAIDRIFEILD
                     ETDEIPDLPDARLLEQPKGKIAFKNVQFGYTSDKILMNQVDFSVKPKQTVAIVGPTGA
                     GKTTLVNLLMRFYELNKGKIEFDGLDITKLSRGELRRSFGMVLQNTWLFEGTVADNIA
                     YGKMDATREQIIEAAEIAQCDHFIRTLPDGYDTIISSENGTLSQGQQQLLTIARVILA
                     NPPVVILDEATSSVDTRTEALIQQAMEAVTKDRTSFVIAHRLSTIENADMILVMKNGD
                     IVEKGTHSELLQSPTLYASLYNSQFQIA"
     gene            complement(12933..14654)
                     /locus_tag="ACG8LA_002098"
     CDS             complement(12933..14654)
                     /locus_tag="ACG8LA_002098"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0204384.1"
                     /translation="MSILKTFLQKNKGLALLTFVMICLEIAGTLGVPKLVAKLIDTGI
                     ASGEASVIKKIGVEMLLVAFLGTIAAVASSYFSALASARFGFQTREKYFRKFQQLSMK
                     DISRFSSGSLLTRMTNDVDNVQQMIVLFCQMILPAPVICVFTILMMFRYSLLLTWVTL
                     ISVVFYVWIVYRLMKRGAPLSLSIQPKMDRITITLREFFTGINMIRAFDNQSYEEKRT
                     NKSFADYANQMIKVNRIFAWVTPIAFLLMGIVYASILWFGGNLVAEGALQIGVVTAVV
                     EYSMLTLAYLMIAAMVLVIIPKSFASLRRIEEILQAEIEIEEETIKTVAEPTFDQTNA
                     AAFEHVTFKYTEISDPVLEDIDFTIPKGKTTAIVGGTGSGKSSLAKLLLRLSDPTIGK
                     VTLGGIPLTQMTQEQIRSHISYVPQKAFLFSGTILSNLQMGNEYASTEELSKAIKIAQ
                     LEELVDTLPDGLDSFVAQGGSNYSGGQKQRICIARALIKPAEIYVFDDSFSALDYKTD
                     AALRAALHKHMSEKTLVIVAQRLSTIQQADNIIVLDEGKIVGQGTHEELLSNCQTYQE
                     FAKSQGI"
     gene            14754..15515
                     /locus_tag="ACG8LA_002099"
     CDS             14754..15515
                     /locus_tag="ACG8LA_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HFQ0204385.1"
                     /translation="MKKMYTIGQVSELFDLPKSTIRYWDEQGLIRSSRQEENDYRLFD
                     IDDIFMLYDIVFYRKLDIPIKQMKNLYGKTLTELYETLDETERRIHKELVVMKQKQKE
                     IREQKKQLKLMIDTNEEEFPVEEIPFDCMISTEFEDIVEIKKFLPNYSSFGMMSMPAS
                     SSQTMYGFFIDPSEVHLFTQDVIWEKKDTAVYRRFLLKSEMNHAERNNILEIRERMYE
                     KGWKTGEVIGQYLLTNTDENNIRTEYYHAWIEMKK"
     gene            16482..16750
                     /locus_tag="ACG8LA_002100"
                     /pseudo
     CDS             16482..16750
                     /locus_tag="ACG8LA_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013720767.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS607 family transposase"
     gene            17422..>19598
                     /locus_tag="ACG8LA_002101"
     CDS             17422..>19598
                     /locus_tag="ACG8LA_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prealbumin-like fold domain-containing protein"
                     /protein_id="HFQ0204386.1"
                     /translation="MRNKFHKLLSMFLVMLIVINQFGNITVLAESLAEQPERSLTIEV
                     DQEEAALGEQFQLRVRGTPDLLNALVIDKSEDLIEGEVKQLNDYERLITYSSQHSGKY
                     ELTARSGDIQSNTVSIEISVPEESTSESFNVPEESTSESFNIPEESLSESFNEARSSE
                     PSITQESQIERQEELLNYDIGISAERPTLPSRHTQTLKGYIQGGAGDILEEYGEMVVR
                     VPRASIGLIEFIRVEVADDSPLKPLAFYQEGTDVVFPFTFDYEGLNEAAQSYTFSITF
                     EVAFFQSGGTEPNNDFQVSLTYAERAANTEFSITPIPSSRPIFSKLYYGSREIDSQGN
                     LGNLLIDGQDVTNSNKFILQVNYEGSRKDGVVVTDVLPQGTTLAPNPTTWSSTGNREP
                     ISGGVRIAEVTNPGEANVRTHYVSEEFVDKVSFNKETNTLVVDFGNLAEGQSYFIEYA
                     LEVTDVDLFNEGRQEDGFSRNRASMTYNNQVMSRDYRLRIPESNLPAISLRKSVDKNV
                     INLNENELTYTLHVSMFSGTRNTLVIEDVLEEGMEFVSFLSDIPSFIDAEVNNGIVRF
                     SANNTIGGPTSFTLSFKVNVEAYAVGDQILNFATLVNSDNRLNTSTVRTRKIDGRIKV
                     IKTDENGQRLAGAKFEILSSDSQVIQEGITAENGEFLSEPLPVGSYQVRETEAPEGYL
                     LDATVHDVFINEYSIEEVTLTIENILDTGGVELIKHAEGSGEVL"
BASE COUNT         6450 a         3460 c         3880 g         5808 t
ORIGIN      
        1 aagagtatta tacaagctaa agcttttctt cattgccact caaatgagtg gcttttttat
       61 gtatcctttt atggattaat gaaaggatgt ttcacatagt tatatttctg tatatttgaa
      121 aagttttact ttgattttta aatagaaaga catttgggtt atattgtgag ataataataa
      181 agaagagttt aaagcgttcc ccaaaaacca ctgccccata agtgtgttac gctttaaact
      241 cttttatatt tgaagccatt aaaaagcata ccatattttt gaaaaaaagt gagaaaaaag
      301 gcttataatt ggagtggtag ttaattagtg acttattttt gattttatag cactgatact
      361 ataaaatata gatatcatca tattacacaa tcttaatact aacttaaaaa atatctcctt
      421 tcataagtat ggtgataaaa tccgttccgg gctacctttt taggtagcct actttaatct
      481 ttgtatcttt ctggatcaac gaaagtatac tttatatagt cataacgccg atgatcgctt
      541 cgagcgtcta gcacatcagt cacgatatca aacaaaaaat atacgtcttt cttcattcta
      601 gttttcgcag cagggatttt aaagtagttc ttattagaat agtagagatt aattaataag
      661 ctatcttcga ttgctaaaaa gaaaacttct gaatcccaca ccttataaaa atctttgaca
      721 aatctattcg aaggatcaaa tttaaaccat aattgcgtct cattaaaaag cataaccatt
      781 actccgatct atttttaaac ttagtctcta cctctaatat atatcgagtt tttattttgc
      841 cttcagagaa tactgtttct ttttttgcag ttacaggttg tttattttcg gaaaaagcta
      901 atatagctaa aattgaaaca tccatctgga atttatcttt tttactgctt tgatcataaa
      961 agtctgcata ttcatcactg atattttttc taataaattc ttccatcata aaaatcacct
     1021 caaaacgatt atacgaactt acgttcttgt tgtaaagcga tatttgaggg gcaaaaaagg
     1081 ggcataattt gactgatatt aagttagcta ttgatatatg aatgacatac aaaaatataa
     1141 aatcttttaa aaatgcttat atatcaatgt ttttgccatt cttttatata tctgttatat
     1201 gtcaaaaaaa tgtgttcaat ttcaatttgt atttgaataa agaggttgtg aaaaagctgt
     1261 cctgcatcaa gtaataagaa cagccaatca aaaacagctt ctcatgtttt tgatttggtt
     1321 ggacttatta ccgcagatat aagcttttga gcaccgtgaa taaagaggtt atgaaatcaa
     1381 cgctctaacc tgagtattag agaaaaaaac gcaaaacata tcatttatgt tttgcgtttt
     1441 ttatttatct ttttttctca atacaatata aaataggcgg ctggttcttt tggttgataa
     1501 accgataatt cagcacatta tatgtttcct gtggcagttt ggaacaaaaa gaatcaacca
     1561 tatccagttc tttttctcca ccttcatgac catagtagac gacaaggatc aatcgtccgc
     1621 gaggcacaag tcgtttcaat atttcttcca tagctgtgcg tgtagtctct ggcatagtga
     1681 tgattgcttt atcacttttt gggagatacc ctagattgaa aatccctgct ttgagatttt
     1741 gttgttcagc tatcacttct cctaacgttt cgtggccttg tagaaacaat gagacacgtt
     1801 cttctaactg acgctgttct agcctttcac gagtagcatc gattgcttgt tgctggatat
     1861 caaaactata gacatgacca gtttttccga tgtgttctgc tagaaaaacc gtatcgtggc
     1921 cattgcccat cgttgcatct acgacgtgat cccctggttg caagatttct tgcagtaatg
     1981 tatggctgaa atgcaaagca gtttgcaaca tcagacgctc acctttttcc gtacatcata
     2041 ttttccttgg aagctatctc tgcgaagaag ttcttcatca attgcattca agacttccca
     2101 ttttttcaag ctccacattg gtccaatcaa ggaatcccac ggcgcatccc ctgtcaaacg
     2161 atggatgatg atctcttttg gtatcatttc cagctggtcg caaatgacat tgacatagtc
     2221 aggacggctc attaattgaa ggcgaccttc atgatagtcc cgcaacattc tcgttttgcg
     2281 catcagatgc atcaaatgga gcttgattcc ttggatatct gaatctaaaa tggtgcgtct
     2341 gacattttct ttcatcattt ctaaactttc gcctggtaat ccgttgatca aatgcgtaca
     2401 aacacggata ttatgtttgc gtaatttagc cacgccatct aaataagttt gataatcatg
     2461 tgctcggttg atcagttttg aagtttcttc aaaagttgtt tgcaatccaa gttctaccca
     2521 taaatacatc cgctcgttca gttcagcaag gtaatcaact acttcatctg gcagacaatc
     2581 cggtcgtgta ccgactgata atcctacgac acctggtaaa ttgactactt gctcaaatcg
     2641 ttctttgatt atttcaactg gcgcatgggt gtttgtaaaa ttttggaaat aaacgatgta
     2701 ttgttggaca tgaggccatt tttgatgcat catgtcgatt tctttctgga attggattgg
     2761 aagagggtct tcaggtgcaa cgatcatgtc tcccgaacca gatacactgc aaaaagtaca
     2821 accgccatgg gcaacagtcc catctcgatt cggacagtca aatcctccat cgatcggcac
     2881 cttgaaaatt ttcccgccaa actcatttcg taaagcgtaa ttccaagaat gatatctttt
     2941 atttccttct gaataaggaa aagtcattaa aagtccttct ttctgtaaga gttatctatt
     3001 tgttttcttt tttctctata cactggataa gtcaggcaca gccaagaaag actgagtaag
     3061 tagccgccga tgatatcagt aggaaaatga acgcccagat aaatgcggct tatcccgaca
     3121 cttactataa taaacatcat cagcaattga agcaatgtgc gtaaggttct tttttgaaca
     3181 aaagctggaa gcagaaatag taaagaaccg taaagaatca tactgcctgc tgcatgtcca
     3241 ctagggaaac tgtaacttgt ttcaactact aagtgcgcca atgaaggacg ctctcgcatg
     3301 aaaaatagtt tgatcaccgg gttgatgatt ccagcaatta caataaatcc agaaacgaac
     3361 caaaatgttt ctgccctttt tttcttatac cacatccata aagccgcaca agcaaataaa
     3421 atgatgacgg taagaggatt accgaattta gtcataaaga gttggtagct gttcagatca
     3481 ggataagaag ctctgacaat gcctgtaaac cactgatcga aaccagaaag ccacgacaga
     3541 tggaacttta cgatccagcc caaaatgaaa aacaggacaa gaaagaagct accagccacc
     3601 tgaaatgatg ttttatattt catacaattc ctcctttgaa gcaatgactt attatagcat
     3661 ttttggtcca gcgaaaaaaa cggtaaagag ataaaaccaa tgtatgattc ctctttgaat
     3721 aaccaatatt cttataaaaa aaataactgt aatcggaaag acattttttg gtaatgcaaa
     3781 tgaaatgtta gggaaataaa atcagtgttt ttcgaaatcc ttttaaacaa gaacgtagac
     3841 gtaggaagaa cttgaaaatg aacagaagtt gttcattacg gtaaattaca atatgattac
     3901 aaaaaacaac aaagctctta aataactttt aataaatatt aagagaagtt ataattatta
     3961 ataatagata aattgaagtt ggaggataga agatggaaaa cattgcaaga aaagaacgga
     4021 gacgtttaga acagaccaaa cgttttcgaa aagcaaaacg aggggcagca atcgtgggaa
     4081 ctgcgatggt aggctgttct gtcgctgccc cattagtaca gccggttcct gttcaagcgg
     4141 atgaaacacc tgttcagttc ggcgcaagaa tcaatacagc ggcatttatc acagaaattg
     4201 ctacttatgc tcaaccaatc gctcaagcca acgatctata tgcatcagtg atgatcgcac
     4261 aagcagttgt agaaagcggt tggggcagta gtgcgttatc tcaagcacct tattataatc
     4321 tttttgggat aaaaggcagc tatcaaggac aaaccgtcta catggatacg cttgaatttt
     4381 taaataatca atgggtaaat aaaaaggagc ctttccgaca atatccttct tttgctgaat
     4441 ctttcaatga caatgcctat gtacttagaa atacttcatt tggcaacggt tattactatg
     4501 ccggtacttg gaagagcaac acgaaatcct atacagatgc gacagcttgt ttgacagggc
     4561 gttatgcgac tgatcctggt tacgcaggca aattaaataa tatcatcgca acttacggat
     4621 tgacccaata tgatacacca gctagcggaa acgcaggcgg tggagcgact acaggtggca
     4681 ataatactgg aagtgcaggt agtactggcg gttcaagcaa ttctggtaat acaaactcag
     4741 gttcagcaac ttcgaccact tatactgtcc aatctggtga ttctgtttgg ggaatctcaa
     4801 ataaattcgg tatcacaatg gatcaattga tccaatggaa caacatccaa aacaatttca
     4861 tttatccagg acaaaaactg acaatcaaag gtagccagga aaatggctct tcgacgaata
     4921 attccggtaa caataccaac tcttcaggaa atgctggtac atcaaacgga ggacaaacaa
     4981 ctggtgcgaa atacactgtt caatctggtg attctgtttg gaagatctca aatgatcacg
     5041 gaattacgat ggctcaattg attgaatgga acaatatcaa gaacaatttc gtttatccag
     5101 gacaacagct aatcgtatca aatggcggtt cttctaatgc tggagcaaat actggctcaa
     5161 atactgggaa tacaagtggc tctagttcgt ccagctcaag ttcttctaat acagcttcag
     5221 gaacgaaata tacagttaaa gccggagact ctgtttggag cgtctcaaat aaatacggaa
     5281 ttacgatggc tcagctaatc caatggaaca atatccaaaa taactttatc tacccaggac
     5341 aacaactgac tgtttcaaac agtggatcaa caaacagcac gtcaggtaat acaggttcgt
     5401 caaccaatac aaataacagc agttcagtta atactggcag cagttcgtct caaggcactt
     5461 ataccgtgaa agcaggtgaa tctgtttgga gcgtggcaaa taaaaacggc atcacgatgg
     5521 atcagttaat cgaatggaat aatatcaaaa acaacttcat ttatccagga cagcaattga
     5581 tcgttaaagg tggaacttcg gcaaatacaa atacaggttc aactacttct gcagcgaaac
     5641 caaatacacc gaatacgtct gctacgacaa gtacatcatc cactggtaat acgatgtata
     5701 ccgtgaaagc gggcgagtca gtttggagcg tagcgaacaa acatcatatc acgatggatc
     5761 agttaatcga atggaataat atcaaaaata atttcatcta tccaggacag caagtgattg
     5821 tgaagaaagg ttcatctcaa tcaacaaacc aacaatcagt tactggttcg aaaacctata
     5881 ctgtgaaatc tggagaatct gtttggagtg ttgctgacag tcatggaatt acaatggctc
     5941 aactaatcga atggaacaat attaagaaca actttattta tccaggtcaa acgttgattg
     6001 tagctaaata aaatagctgt tcgaagaaat aacgattgaa ttccacaaaa atatttgtta
     6061 ctataaggct acttaaatat gacaacactt gaaaaggaag tagtaaaaag actgaagttt
     6121 cagagagcgc atggctggtg agaatgtgca cggatgcttt tgaactcgcc tttgagttgc
     6181 ccttgctgaa tacccgagta agcaagcggc ggtgacggcc gttacaacgt tcgaggcctt
     6241 ttcactaagg taaaattagg tggtaccgcg tagattacgt cctataaaaa gagcaatctt
     6301 tttataggat ttttttattt cttttgtgaa gtttgagaaa acaaagcaaa aggaaataaa
     6361 aataaacaga ttctgccggt tttttcgtta tatttataat agaaacaagt gttttcaata
     6421 gaacaggagg acagcaaatg agttacaatc ataaagaaat tgagaaaaaa tggcaaaaat
     6481 actgggcaaa aacgaatact ttcaacaccc atgatgatcc tgaaaagcca aaattttacg
     6541 cactggatat gtttccctat ccatccggtc aagggctaca tgtagggcat cctgaaggtt
     6601 atacggcaac ggatatcctt tcacgtgtga aaagaagtca aggatacaac gtgctgcatc
     6661 caatggggtg ggatgcattc ggtctgcctg ctgaacaata tgcgctagat acaggaaacg
     6721 atccagctga gtttacccaa aaaaatatcg aaacattccg acgccaaatc aattctttag
     6781 gatttagtta tgactggaat cgcgaagtga atacaactga tccggagtat tataaatgga
     6841 cacaatggat ctttacgaag ctttatgaaa aaggtctagc ttatgaagca gaagtagcgg
     6901 taaactgggt acctgaatta ggaacagtta tttcaaatga agaagtgatc gatgggaaaa
     6961 gtgaacgtgg tggctatgat gtagtcagaa aaccaatgcg ccaatggatg ctgaaaatca
     7021 ctgcttatgc tgatcgctta ttggatgatc tagaattagt tgattggcca gaaagcatta
     7081 aagaaatgca aagaaattgg atcggtcgtt cagtaggagc aaatattgaa tttaaagtgg
     7141 ctggtacgga taaatcctat accgtattta cgacacgacc agatactcta ttcggtgcaa
     7201 cttactcggt tcttgcacct gaactagatc ttgttagaga aattacgacc cctgaacaaa
     7261 aagctgctgt agaagcttat atcgaagaga cagctaaaaa atcagatcta aagagaacgg
     7321 atcttgcaaa agaaaaaaca ggagtattta ctggtgctta tgcaatcaat ccagttaatg
     7381 gcaaggaaat cccaatctgg atcgccgatt atgtattatc ttcatacggc acaggagcca
     7441 tcatggctgt tccagcacat gatgaacgtg actttgaatt cgctcaaact ttcggactag
     7501 aaattcttcc agttatcgaa ggtggagatg ttgaaaaagc tgcttacaca gaagatggta
     7561 cgcacatcaa ctctgaattt ctagacggca tgaacaaaca agaagcaatc gataaaatga
     7621 atgaatggct agaagaaaat ggcgtaggga aaaaagaagt cagctatcgc ttacgtgact
     7681 ggctattctc ccgtcaacgt tactggggtg aaccaatccc aatcatccat tgggaggacg
     7741 gaacagtcac agctgtccca gaagaagagc taccattacg gttgcctaag acaaaaaaca
     7801 tcaagccaag cggtactgga gaatctccat tagcaaatat cgaggagtgg gtcaatgtcg
     7861 ttgatcctgt aacaggtaaa aaaggccgtc gcgaaacgaa tacaatgcca caatgggcag
     7921 gaagctcatg gtattacctg cgttatatcg accctcataa caaaaaagaa ctagcagatt
     7981 atgaaaagtt gaagcgttgg ctaccagttg acatctacat tggtggagca gaacatgcgg
     8041 tacttcattt actatatgca cgattctggc ataaattctt atacgatatc ggtgttgttc
     8101 ctacaaaaga accattccaa aaactataca atcaaggaat gatcttaggc gaaaacaacg
     8161 aaaaaatgtc aaaatctcgt ggtaatgtag tcaatcctga tgatgtggtc gaaacttacg
     8221 gtgcagatac actgcgcatg tacgaaatgt tcatggggcc attagatgct tcgattgctt
     8281 ggagcgaaaa tggcttagaa ggaagccgta aattcttgga tcgtgtatgg cgtttgatcg
     8341 ttgatgagaa caataaaatg cgtgaccgta tcactacatt gaatgatggc aagcttgata
     8401 aagtgtatca tcaaacagtg aaaaaagtga cagaagacta tgaaaatctt catttcaata
     8461 cagcaatctc ccaattgatg gtctttatca atgaagccta taaagtggac gctctgcctt
     8521 atgaatatat cgaaggattt gttcaactac tcgcaccgat tgctcctcac atgggtgaag
     8581 aactatgggc aatccttgga aatgatggtg gtatttctta cgcaccatgg ccaacatacg
     8641 atgaagcagc acttgttgaa gacgaagtag aagttgtttt ccaagtaaac ggtaaagttc
     8701 gtgcgaaaag caatgttccc cgagacttag gaaaagatga gctagaaaaa gcagcattag
     8761 ccaatgaaat agtgcaagaa tatattgaag gcaaaacagt cagaaaagtt attgcggtac
     8821 caaacaagtt agtcaatatc gttgctaatt aattggctct ttgtcaataa ggactgatga
     8881 gttgtgcaaa atcaaatctg ggccagaatg aacttcattc tgtctcagat tttttgttat
     8941 ttcaaattga ttaattgatt gatcaaaaag gttttgattt tcatgttctc aaacacgttc
     9001 aatgtctttt tcttctgaat ggtcttgtaa gagatctctg taatcatcaa atttttgtct
     9061 attaatctta gtattttttg atgtataaac tacctgaaat tgagagtaca taccaaattc
     9121 ataaattttt tattagtggg actagtgatt gtatggattt tgacgcataa tgaatgaagt
     9181 atgagaaaag gagagacaaa tggatcaaga actatttatt atcgaagtat tatcagctaa
     9241 acaaaaaatt atcgagaaag cgaaaaaaag agcgaaaaga ataatgttca agcttttaag
     9301 cttagtattt ttctctggtt tgcttttttt cggagctgta tcgttcctat atcgccatat
     9361 gagtgcagta gtccgttcag ctgaagggat gcaaaaatta aataatttgt atcacttttc
     9421 gtggggagtt ggcggaataa caattgttgt gcttattgtt tttcttctac ttatttggct
     9481 ccgttaccat caattgtcgc gtcatttcga tcaatggctt agtcaaagag cacaacagtt
     9541 tttacataat aaaccaactt ctcaagatga tgactatctt tattttgaga agacttcgac
     9601 gagtcaagct tttcggatac aaaaaagtga ttgccagtta ttgctgagat cacttgatga
     9661 tttacctatc tacttaggcg aaagcaaatc aaaattcgga atgaacacat tccatatttt
     9721 tttactagaa aacgaaccca gatgggaaaa aagccagtct tcgcctggtg gatacctgac
     9781 aactaagatg agtacattag tcactggttt tttcctcatt cttttagctg gaacaatcta
     9841 ttatgggaga tacactcagc caaaaatgtc ttctcatata aatgctgctt ctcacatgac
     9901 aatgaactca actaacgata cgcatataca aaagacaaat gaagggttgt tagctgatcc
     9961 taagcaaaag gtaaatttga caacacaaaa gataaatgat ctcaaacttg atacagagac
    10021 gcactctctc tatatgacaa cagatagtgg tgctaattgg gtatttgtgc cgattgattc
    10081 gcaatggttg cgttttggcg aatacaccct gacaacgggg ctgattcctg aaggttattg
    10141 gatggacaac acatatgata tttccgccga tttctcatgg tttatctatt cttctgggga
    10201 tgatgtacgt ctgctgactt caagagataa tggtaaaaca tggcaaacgt ctattatcac
    10261 ccaatcagtt cagccgatac gttatcgaaa agcggtattt tatggcaacg atggtctatt
    10321 tatctgtaca tcagccagtg ggatgtctgc agaaactttg tacatttaca ctactatgga
    10381 tggcggaatc acttggataa aaagtggaag tacaatgatc aatcagccag tacaaaatgt
    10441 cagcttcgtt acaacttctt taggttttgt ttcgacacgt gaaagtttgt tttatacaaa
    10501 caacggagga cgctcattca aagaatcagt tctgtcgatt ccggaaaact atcagacagg
    10561 ggggatagat ctttttcaat caccaaatga agttactcaa ataagcgcga atacgttaga
    10621 gacaaaattt tatttgttga aaaaaggacc aatcgatgca gggaaaatgt ttgcctgcct
    10681 cttccgttca actgataacg gggaaacatg gcaattcgtt cagcaactat cgcaagtaga
    10741 acaaggagat taaagaagag agattgtgag cctgacgttc agcaccgagt cacaagaaac
    10801 aaattcaaaa aacagcttct catatttgtt gaatagtgta actcgtgatt cggagttgac
    10861 aagagcaaca agaagcgatt ttgaagtata gcttctcgta ttttacaaga tcgtgtctta
    10921 ttgccgatag gttgtctctt gaacaccgtt tattcgtaaa aagggattgt gacaagtctt
    10981 ttgtcactac ttaccgaacg aaactgaagg agctatccaa aaagtatcat tagtattatt
    11041 ctttgtgttt ctagtggcac cactagtaca tttaaaaaag ctatcgatca tggactaatc
    11101 atacatgatc gatagctttt tagataatgt ttgttacgct atctgaaatt gactattata
    11161 aagactggca taaagcgttg gtgattggag tagttcagaa tgtgttcctt tttcgacgat
    11221 atcgccattc ttcattacaa ggatcatgtc tgcattttca atcgttgaca aacggtgtgc
    11281 aatcacaaaa cttgtcctat cttttgtcac agcttccatt gcttgctgaa tcaatgcttc
    11341 tgttcgtgta tctacgctag aagttgcttc atctaaaata acgacaggag gattcgctag
    11401 aatgactcga gcaattgtca ataattgttg ctgtccttga gataacgtgc cgttttcgct
    11461 agaaatgatc gtatcatatc cgtctggcag tgttcgaata aagtgatcac attgtgcgat
    11521 ttcagccgct tcgataattt gttctcttgt ggcatccatt ttcccgtagg cgatattatc
    11581 agctaccgtt ccttcaaaca gccaggtatt ttgtaaaacc atcccaaaag aacgacgtag
    11641 ttctccacgt gaaagcttgg taatatcaag accgtcgaat tcgatctttc ctttattcag
    11701 ttcataaaaa cgcatcagca gattgactaa agtcgttttt cctgcaccag ttggaccaac
    11761 gatcgctacc gtttgttttg gctttactga aaaatcgact tgattcatca atattttatc
    11821 tgatgtgtaa ccaaactgta catttttgaa agctattttt cctttcggtt gttctaaaag
    11881 tcttgcatct ggaaggtctg gaatttcatc tgtttcatct aatatctcaa atatcctatc
    11941 gattgctgcc attgcggatt ggatcgagtt gatcacataa gaagcggtag aaattggttc
    12001 agaaatctga ttgatgtact gaagataagc ttgtaagaag ccgatcgtca caccacctga
    12061 tagaacaagc atagcaccga ataccgcact tatgatgaag gcgagttgat taatgaaacg
    12121 aatggccgga tagatagcac agttcataaa ttgagcacgt ttaaaagcgt tgtattgctt
    12181 tttatttact tcgtgtatag cagcttctgc atgagcttgc tgattgaatg ttttgaccac
    12241 tagattacca gctaagattt cttccattcg attatttaaa acacccagtt catactgatt
    12301 ctgttcagaa atctgtttgt ttttgttcgc aatcttagtt gtaacaattg aactgccaac
    12361 gatcagcaat aagacgagca aagtaagctt gctttcgata taaaacagca tcagaccagc
    12421 agcagctatt gttacgacag aagtaaaaaa ttgattgata cctgtcaata acacttgaga
    12481 aagttgattg agaccggtag ttgtccgact aatgatgtca cctacttgat gattgtcaaa
    12541 aaacgacatc ggtaatgttt tgaatttttt tgtgatttct tttcgcaccc tcaatgtgat
    12601 cttttcgctt aacgctgcca ttgtccgttc ctgaataaat gaagtgatgc tgcttaagac
    12661 tgaacagccg atcagcaata agacagggaa caacaatgct tgtttgatat cactgaaaga
    12721 aagctgtcca atacctgttt ttcttatttc tgataagaga tcatcgatcc cgattcccat
    12781 gatcaagggc atggctacga ctaataggtt cccgaataaa ctgcatagaa acaatccgta
    12841 aaaatattta tgttcaggtt tgatcatttt ccaaaaacgt atcaaagcac gcgtgttcaa
    12901 cgtttttttc ttttccatcg tatcccttct ttctatattc cttgtgattt tgcaaactcc
    12961 tgataagttt ggcaattaga cagtagttct tcatgagtac cttgtccaac gatttttcct
    13021 tcatctaaaa caatgatgtt atctgcttgt tggattgtac tgaggcgttg agcaacaatc
    13081 acgagagttt tctccgacat gtgtttatga agggctgctc ttaatgctgc atctgtttta
    13141 tagtctaaag cggagaaact atcatcgaat acatagatct ctgctggttt gatcaacgct
    13201 cgagcaatac atatccgctg tttctggccc cctgaataat tagaaccgcc ttgagcaaca
    13261 aagctgtcca atccgtcagg aagggtgtcc actagttctt ctaattgagc gatcttgatc
    13321 gctttagaca actcttctgt tgaggcatat tcatttccca tctgcaagtt gcttaaaatt
    13381 gtcccgctga ataagaaagc cttctgaggg acataactga tgtgggagcg gatctgttct
    13441 tgagtcattt gagtaagagg aataccacca agggttactt ttcctatcgt agggtcacta
    13501 agtctcaaga gaagtttcgc caaactactt tttccagatc cggtcccgcc aacgatcgct
    13561 gttgtttttc ctttaggtat tgtgaaatca atatcttcta gaactggatc agagatttca
    13621 gtatatttaa atgtgacatg ttcaaaagca gctgcatttg tctgatcaaa ggttggttca
    13681 gctactgttt tgatcgtctc ttcctcaatt tcgatctctg cttgcagtat ttcttctatc
    13741 cgtcgtaatg aggcaaacga tttagggata atgaccaata ccatagctgc gatcatcaag
    13801 taagcaagtg tcagcataga gtattcgact acagcagtca cgacaccgat ttgtaatgct
    13861 ccttctgcta caagatttcc gccaaaccac aaaatagaag cataaacgat tcccatgagc
    13921 aaaaaagcaa ttggagtgac ccaagcaaat attcggttca ctttgatcat ttgattagca
    13981 tagtcagcaa agctcttatt cgttcgcttt tcttcatatg attgattatc aaaggcacgg
    14041 atcatattaa tcccagtaaa gaattctctc aatgtgatgg tgatccgatc catttttggc
    14101 tggatactca aagataaagg tgcccctcgt ttcatcagtc gataaacaat ccatacataa
    14161 aaaacaacag agatcaatgt aacccatgtt agtaatagag aataacgaaa catcatgaga
    14221 atggtgaaaa cgcaaataac cggtgctggt aagatcattt ggcaaaataa aacaatcatt
    14281 tgctggacat tatcgacatc attcgtcatt cttgtcaaaa gagatccaga actaaaacga
    14341 ctgatatcct tcattgacag ctgttggaat ttacggaaat atttctcccg cgtttggaat
    14401 ccaaacctag cggaagccaa tgctgaaaag taactagagg caactgcagc gattgttcct
    14461 agaaacgcta caagcagcat ttcaactcca atttttttta taactgaggc ttcgccactt
    14521 gctatacctg tgtcgatcag ctttgctact aattttggta cacctaatgt accggcgatt
    14581 tctaaacaga tcatcacaaa ggtaaggaga gcgagtcctt tgtttttctg taagaatgtt
    14641 tttaagatag acatattatt cctccttttt tcctgatact tttcgattct ataccttcaa
    14701 gtaacttgaa ggtcaataga aaaaagaata aactgaaaaa gaggtgagaa aaaatgaaaa
    14761 aaatgtatac gattggccaa gtatcggaac tatttgattt gccaaaatca acgatccgct
    14821 attgggatga acaaggatta atccgttcaa gtagacaaga agagaatgat tatcgattgt
    14881 ttgatatcga tgatattttt atgctttatg atatcgtttt ttatagaaaa ttagatatac
    14941 cgatcaaaca gatgaagaat ttatatggaa aaacattgac ggagttatat gagacacttg
    15001 atgaaacaga aagaagaatc cataaagaac tggtggtgat gaaacaaaaa caaaaagaga
    15061 taagggagca aaaaaaacag ttgaaattga tgatcgatac aaacgaggaa gaatttcctg
    15121 tagaagagat cccttttgac tgtatgatct caacggagtt tgaagatatt gtggaaatca
    15181 aaaaatttct acctaactat tcaagctttg ggatgatgag tatgccagct tccagttcac
    15241 agacgatgta tggatttttt atcgacccta gtgaagtaca tttatttact caagacgtga
    15301 tttgggagaa aaaagatacg gctgtttatc gtcgattctt attgaaatcc gagatgaacc
    15361 atgcggaacg taataatatt ttagaaatca gagaaagaat gtatgaaaaa ggatggaaaa
    15421 caggagaagt gatcggccag tatctattga cgaatacgga tgaaaacaat atcagaactg
    15481 aatattatca tgcatggata gaaatgaaaa aataggaaat atgtgtttaa gataactcga
    15541 aaatgatggt tgttttagtt ataaagaaaa attttctggt tcgattacgg gtttaatgtg
    15601 ggggattatt agtcgtggat agatagaatt ttagtttttt agaggaaata tgtctttaaa
    15661 aatggaatgg ttgcaattct tagcgatata tacgatgtaa ttgtcctctt aaaaaagtat
    15721 ggaaaaataa ttgtattggg tgttatgtat aattcatggt gaactgagac taatgagaag
    15781 aaaaattcat attgttatga gtgagattgt atcagatgag aatgataaat taaataggtg
    15841 cataaaagca ttacacttaa aatacattgt tgcttacatt attacaatat gttaataagg
    15901 caaaaataaa tagatggatt gaataaacat attttttaat caaatagtcc ctactgtgac
    15961 tttcctcagc tatcggtgat actaccgata gcattttttt gcttataaaa taattataag
    16021 tatttagaga tttttcttct aacattcttc aaacaagaaa aatcacaaag gttattgtta
    16081 tttttatata ttctttttaa gaatgattgt ttttttatag aaattttaaa aaataaaaca
    16141 cgttattgat ggatagttag tttgttattt ggtaatatta tagaagttga ctggtagtga
    16201 tttatttttc gtcgttttat aaaaatgtta ttttttggaa aaattcacaa atatgtaacg
    16261 aatgtttttc tggaatttgc tgtgttaaaa agcagtatga ctaatataaa tactattgtc
    16321 atttatgcaa ttttttatgg atagtaattt tagaggggaa tcaatgaagg aagaatagaa
    16381 gggaaaaata gttgcaaata cgccagttag caaaaatagc aatacatctt caagctttaa
    16441 aattcgagag aatcatcttg gtagtggaat caactacaac aaaaggatta aaccaattaa
    16501 tagatagaat taccaatgga aaaatagaaa aggtagttat tctatacaaa agttgtttaa
    16561 ttcgcttcgg ttatgaactt agtgaaaccc tttgcaatat atggtacaga atatagaaat
    16621 tattgacatt acagaaaatg atgaagattt aatacagatt gtcactattt gtagatacct
    16681 tttacaagga aaccgagcca ataaagctaa gaagatgatt aaggagttga tggaagacga
    16741 tacaagttaa gaaagtgaaa ctacgcccaa ataaagagca aaaagagtaa ttggacgtgg
    16801 aaaatgcaag aaatgaacca tcgattcggt ggacagttta ttagtaatga cggtttgaga
    16861 acatccatga cgagaatgaa ggaacatcct aaatgcgttt agttgaacca agtgccaaat
    16921 aatatggcca aataagcgat cagttatcga tgaatcccaa gtattctaaa ctatatattc
    16981 attttgatgc taagcattga tatatttttt tgggattgat gaaggttaac caatacaggg
    17041 actcactgat gaaattctag agtctgacct tggtatcaac gatttagtga ttgtttctaa
    17101 tggaaaagta taaaagtata taagtacatt aacaaaataa ctattagggt tacgctccag
    17161 cttgtgcaag gcactggcag gaggaatcgt gaaatcataa ttatggttaa gccacacgga
    17221 caactaaaag tcatacaaag ctatcgaatc aatcaacaga agacaatcgg caatcattag
    17281 ctttgtttac agcttacatt gcaacgcttg agttgaaccg aaaatacgag ggaggtaacg
    17341 cagccatttt gagttgggga atctttttag aaaattatcg ggtaccttgt tgtttagtca
    17401 aaattataag ggggagtaat agtgaggaac aaatttcata aactgttaag tatgtttcta
    17461 gttatgctta ttgtgatcaa tcaatttggg aacataacgg ttctagctga gtctttagca
    17521 gaacagccag agcgttcgct gacgatcgaa gttgatcaag aggaggctgc tttgggtgag
    17581 cagttccagt tgcgagtcag aggaacacca gacctgctaa atgcattggt cattgataag
    17641 agtgaggatt tgattgaagg ggaagtgaag caactcaatg attacgaacg tctgattact
    17701 tattcttccc agcattcagg taaatacgaa ttgaccgcaa gaagcggtga tattcaatca
    17761 aatacggtct caatagaaat cagtgtacca gaagaaagca caagtgagtc ttttaatgta
    17821 ccagaagaaa gcacaagtga atcttttaat ataccagaag aaagcttaag tgaatctttt
    17881 aatgaagcca gatcatctga gccatctata acgcaggaat ctcagattga aagacaagag
    17941 gagctcttga attatgacat cggcatctct gctgagcgcc ccactttgcc gagcaggcat
    18001 acacaaacgt taaagggata cattcaagga ggcgctggcg atattcttga agaatatggg
    18061 gagatggtcg tacgagttcc tagagcatcg attggcttaa ttgagttcat tagagtggag
    18121 gtcgctgatg attcaccttt aaagccactg gcattttacc aagaaggcac agacgttgtt
    18181 tttccattta cctttgatta tgaaggatta aatgaagccg ctcagtcgta tacattcagt
    18241 atcacgtttg aagttgcttt ctttcaatca ggcggtactg agccaaataa tgactttcaa
    18301 gtgagtctta cttatgctga gcgagcagca aacacggaat tttcaattac gcctattcct
    18361 tcatcaagac ccattttttc gaaattatac tatggctcta gagaaatcga cagccaagga
    18421 aatcttggga atctgctgat tgacgggcaa gacgtgacca acagtaataa atttattttg
    18481 caggtaaatt atgaaggatc acgaaaagac ggtgtagtgg ttaccgatgt actaccgcaa
    18541 ggaacaactt tggcaccgaa tccgactaca tggagttcca ctggaaatag agaacctatt
    18601 tcaggtgggg ttcggatcgc agaagtaacg aatccaggtg aagcaaacgt tagaactcat
    18661 tatgtttccg aggaatttgt ggacaaagta tcttttaata aggaaacgaa tacacttgtt
    18721 gtggactttg gtaatctagc agagggtcaa tcgtatttta ttgaatatgc tcttgaagtg
    18781 accgatgtcg acttgttcaa tgaaggaaga caagaggatg ggttttctcg gaatcgagcg
    18841 agtatgacct acaataatca ggtaatgagc cgagactacc gcttgagaat ccctgaaagt
    18901 aatcttccgg caatctcttt aagaaaaagt gtggacaaaa atgttatcaa tctcaatgaa
    18961 aatgaactaa cgtatactct gcatgtctcg atgttttctg gaacaagaaa tacgcttgtt
    19021 attgaagatg ttttggaaga aggcatggaa tttgtgtcat ttctatcaga tattccctct
    19081 ttcattgatg ccgaagtcaa taatggaata gttcgtttca gtgcgaataa tacgattggt
    19141 ggtccgacaa gttttaccct ctcttttaag gtcaatgtag aggcgtatgc ggtcggcgat
    19201 caaattttaa actttgcaac gcttgtgaat agtgacaatc gattgaatac gagtactgta
    19261 agaacaagga aaatcgatgg gcgtattaaa gtaattaaaa ctgatgagaa tggccaaagg
    19321 ctggcaggag caaaatttga aattttatca agcgattcac aagtgataca agaaggtata
    19381 acggcagaaa acggagaatt tttaagtgaa ccgcttcctg taggtagcta tcaagtccga
    19441 gaaacagaag caccggaagg gtatctttta gatgcgacgg tacatgatgt ttttataaat
    19501 gaatactcca tagaagaagt gacgttaacc attgaaaaca tccttgatac gggtggtgtt
    19561 gaactaatta aacatgctga aggcagtggt gaagtcct
//
LOCUS       DAZKKZ010000055        19538 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.056, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000055 DAZKKZ010000000
VERSION     DAZKKZ010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19538)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19538)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19538
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.056"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(142..306)
                     /locus_tag="ACG8LA_002102"
     CDS             complement(142..306)
                     /locus_tag="ACG8LA_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204387.1"
                     /translation="MKNLIAGGFLFVGGGILMNTDNFGNVIPFLGAACALIGVGMLIY
                     FVFSDDGKYG"
     gene            601..1929
                     /locus_tag="ACG8LA_002103"
     CDS             601..1929
                     /locus_tag="ACG8LA_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="C1 family peptidase"
                     /protein_id="HFQ0204388.1"
                     /translation="MKAITPDMTTKFNKQFQANIKQQALQRAVVKNGITASAENVSAH
                     VENTPVFSIDLATGKVANQMQSGRCWMFAALNTFRHKMLNQFHLKEFELSQNYTFFWD
                     KYEKANYFYENIIATGKEAIDSRKVAFLLATPQQDGGQWDMIVSLFQKYGVVPKSVMP
                     ESANSSNSRDLNNYLNKLLRKDAVVLRKMVAQGETLDAIEEKKEEMLESIYNFLAISL
                     GTPPKEFDFEYRDEEKNYHLDRGLTPQIFYDKYIGVKLDDYVSVINAPTKDKPFNRSY
                     TVEMLGNVVGGKEVKYLNVDMETFKKLAIAQLEEGESVWFGCDVGQSSTRTSGIMALD
                     AYSMDDLFDTDFTMTKAERLDFGESLMTHAMVLTGVDLVDGQSTKWKVENSWGEKVGK
                     NGFFVMSDAWMDEYTYQIVVRKDLLTKEQLNAFNEEPIVLSPWDPMGALA"
     gene            2131..2964
                     /locus_tag="ACG8LA_002104"
     CDS             2131..2964
                     /locus_tag="ACG8LA_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructosamine kinase family protein"
                     /protein_id="HFQ0204389.1"
                     /translation="MDIQTVLSDLKLNGKVIPVVGGDVNQTYRIKTEHRAYFLKIHPN
                     VKKGFFEAEVDGLKELSAFVRVPDTYMLGETSEGAYLLMEWIEPGKGDQRDLAAALAN
                     LHQQTAPQFGFRKDNYLGTLVQKNSFEEDWWTFFFKDRLESQISLAEETNRWNVQRQE
                     KYLRFKERVLKSVEPKKITPRLLHGDLWSGNVFFDQQGHPVFVDPAVSYGNREQDIAM
                     SQLFGGFRPEFLDAYQTIFPLEKGWKDRLPIYQLYYLLAHLNMFGESYGSQVDQLLEN
                     F"
     gene            2980..3717
                     /locus_tag="ACG8LA_002105"
     CDS             2980..3717
                     /locus_tag="ACG8LA_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016790 - thiolester hydrolase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-ACP thioesterase domain-containing protein"
                     /protein_id="HFQ0204390.1"
                     /translation="MAKKYTKKHEVSYYECDINQTMTFPSMLGVVIKTSEDQSDQLGR
                     GSEFVNSFGLTWVITNYSMEINRLPRVGEVISVTTQAMEYNKFFCYRNFWIHDEDGKE
                     LVKIESVFVLMDFVNRKMSSVNEEIIAPFESEKIKKIKRQEKIEKIDSGFMLPYRVRF
                     YDIDSNQHVNNAMYFNWIIDVLGYDFLTTHVPEKVIIRFDKEVEYGNEIESHFEQIPI
                     ENGVKTKHEIRMQEQLYCEANIIWKNK"
     gene            complement(3872..4840)
                     /locus_tag="ACG8LA_002106"
     CDS             complement(3872..4840)
                     /locus_tag="ACG8LA_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HFQ0204391.1"
                     /translation="MKKILVLHTGGTIAMKENMLTGGVSPDVANPLLDAEITIPKHVE
                     LLVEDIFNLPSPHIMPSHMLVLKERILSAYASGISGVVITHGTDTLEETAFFLDTTIG
                     NKLPIVLTGAMRSSNELGSDGLYNFESAIRVASCEEALDKGVLVVMNDEIHSARYVTK
                     THTTNVATFRTPTLGPIGLVTKNRILFLQELLETKRLDISAVDGTIPIVKAYAGMQGD
                     LLEAIAHTKVDGLVIEALGAGNLPPQALAALEKLLVQKIPVVLVSRCFNGIAEPVYDY
                     EGGGKELEKMGIIFCNSINSQKARLKLLIAVNYGLSGEELISFIQN"
     gene            5072..5905
                     /locus_tag="ACG8LA_002107"
     CDS             5072..5905
                     /locus_tag="ACG8LA_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF72 domain-containing protein"
                     /protein_id="HFQ0204392.1"
                     /translation="MIRIGLTSFKEHDKLTGKKNNTLYEYAGFLPLVELDTAYYGIPR
                     KSSVENWISEVPESFRFVVKVYQGISGQGDWKPYYQTEEEMIAHFLDVMSPMVDAGKM
                     FCFLVQFPSSFKCTKENVQYLRKLRKWFEGYPVSIELRDYSWYSDEFLERTRNFMSRA
                     AFSLAIIDEPQLLNTTIPFDPFVTNPNFALFRFHGRNAQGWQANDKEWRKKRTLYRYS
                     EKELQELAHEVKVVDSKTKEVGVIFNNNSGGDAAENALALQKILNIKPDGLNPTQMDL
                     F"
     gene            5939..6778
                     /locus_tag="ACG8LA_002108"
     CDS             5939..6778
                     /locus_tag="ACG8LA_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFQ0204393.1"
                     /translation="MIKAIFFDIDGTLVTNRSKALESTKQAIEYARKNGILCGVATGR
                     SPVKIKEIIDELELDMYVVYNGQLVFTADRTIIDHPFEQKVLEHIVEFADENHRQIVF
                     GARNRLDGSTTMLLGQSIFIKRLVSFLPRKFPVRLMKKILQVFSPHRQKDRYETLEIL
                     KEPIYQCILLSPESEQKKLEHRFPECTFQRSNTYTVDIIPKGGSKLLGIQAFANAVEI
                     EMEEIMAFGDHYNDIEMLKGVGIGVAMGNAQIEVKHAADFVTQSNEEDGIYEGLKHFG
                     LIY"
     gene            6804..7359
                     /locus_tag="ACG8LA_002109"
                     /pseudo
     CDS             6804..7359
                     /locus_tag="ACG8LA_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377553.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
     gene            7558..9279
                     /locus_tag="ACG8LA_002110"
     CDS             7558..9279
                     /locus_tag="ACG8LA_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HFQ0204394.1"
                     /translation="MGNNVIIGIVIAIIIVAIVVFLVSYLMKKKNQDRLDALEKRKEE
                     LFDLPVIEEVDDVKKMHLVGQSQNTFREWSQKWNDISTSSFAELESQIFEVENLNESF
                     RFLKGKKAVVEAEATMDQMEKQVTEIREGLKELRETEERNSLAVQQALDVYEELKEKV
                     REDEHEYGPALFELQKQIKVIEKEFTQFVTLNTSGDPVEAREVLDKAEKHTYEVEALM
                     KKIPPLYEELHTTFPEQLEEISDTYEKLMEEQYVFPEEDLAEDIAKVSRRIENSLANL
                     EKTEVETVEFENRETADLIDSLYDILEREMEAQRYVKTNQSTIAEYIKHTTKNNRQLL
                     IELDHTSQSYTLNHNEIGRVRGFQTEVEEMERQNEQMIPQIRQHEIPYSEVRTFYKTV
                     FKVLEDIEKQQVEIDDSLHELRKGEKEAQEKIDTFEFKLRSLKRFVEKQRLPGLPNDY
                     LEFFFVATDRIEELSVVLNKIRVNMEEVNRLVALCEEDLELLDKKTHDLVDAAALTEQ
                     MLQYANRYRHTHEEVREAIDKSYYLFNKEYHYQEALDEIGTALERVEPGAFKRIEDFY
                     FNHPDLV"
     gene            9444..10586
                     /locus_tag="ACG8LA_002111"
     CDS             9444..10586
                     /locus_tag="ACG8LA_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase family protein"
                     /protein_id="HFQ0204395.1"
                     /translation="MIYFDNSATTPIFPQSLDAYVKTSQRIIGNPSSLHDLGNQANRL
                     LQQARKQIADLIHVEPEEIYFTSGGTEGDNWVLKGTMIEKREYGNHMIISGVEHPAVS
                     ETAEQLKELGIEVSIAPVDKRGFVRVDELKELIRKETVLVSVMAVNNEVGSIQPIQEI
                     SDLLDDFPKIHFHVDAVQAIGKVPFSQWLTERVDFATFSAHKFHGPRGTGFIYWKKGR
                     RLAPLLTGGGQERNQRSGTENVPGIVAMVKALRLSLEIKEQKPEQTQRLKVALINALK
                     TYEKVTIFSEGTDYAPHILCFALKGIRGEVLVHALEEKQIFVSTTSACSSRKHMASST
                     LHAMHVPNDLATSAVRISLDENNSLAEVEQFMIIFKQLYKKFSAIN"
     gene            10602..11813
                     /gene="thiI"
                     /locus_tag="ACG8LA_002112"
     CDS             10602..11813
                     /gene="thiI"
                     /locus_tag="ACG8LA_002112"
                     /EC_number="2.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140741 - tRNA-uracil-4 sulfurtransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uracil 4-sulfurtransferase ThiI"
                     /protein_id="HFQ0204396.1"
                     /translation="MKYSEIMVRYGELSTKGKNRKSFIMQLAQNVRQALKDFPEIKIH
                     ADRDRMHLLLNGADGQLVIPKLAKIFGIQNFSPSIRVEKDVEVLKQAVQDIMKEIYTG
                     KETFKIIAKRSDHQFELTSNELNQTLGNAVFDIFPHIQVQMRQPDIPLRVEIRRDGAY
                     LSYETIKGAGGLPVGTSGKGMLMLSGGIDSPVAGYFAMKRGVEIEAVHFASPPYTSEQ
                     ALQKAKDLTAKLAPYVGTIHFIEVPFTEIQEEIKKSVPQGYWMTITRRMMLRLTDEIR
                     RIRHGLVILNGESLGQVASQTLQSMVAINEVTNTPIIRPVATMDKLEIIEVAEQIDTF
                     NLSIQPFEDCCTIFAPPQPKTRPQLEKVHQYEERLAIDEMIQRALAGLKMEEIQAESS
                     NEKTEEFSELL"
     gene            12386..13033
                     /locus_tag="ACG8LA_002113"
     CDS             12386..13033
                     /locus_tag="ACG8LA_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA];
                     GO_process: GO:0051775 - response to redox state [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HFQ0204397.1"
                     /translation="MREKTDTLPKATAKRLPLYLRYLKMLDDSGISRIKSNEFSEITQ
                     IPSATIRRDFSQLGELGRSGYGYDVPFLIDVFNNILNTKEEKRIALVGYGNLGKALKH
                     NNFRRNENLNIVCVFDNDPALINRVIDGEMIYPIDRFAEIAKAKNVTVAISTVPSKYS
                     QSAIDEIVKGNVTAILNFAPDRVTVPAYVNVQYIDLTTELQTLIYFDENYSEVFS"
     misc_binding    13162..13378
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            13426..16071
                     /locus_tag="ACG8LA_002114"
     CDS             13426..16071
                     /locus_tag="ACG8LA_002114"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0004832 - valine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006438 - valyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HFQ0204398.1"
                     /translation="MTEENNLSTKYNPQEVEAGRYQHWLEQDLFKPSGDKKAKPYSIV
                     IPPPNVTGKLHLGHAWDTTLQDMLIRQKRMQGYDTLWLPGMDHAGIATQAKVEAKLRE
                     QGISRYDLGREKFIDQVWEWKEEYASHIREQWAKMGLSLDYSRERFTLDDGLSEAVRK
                     VFVTLYEKGLIYRGEYIINWDPQARTALSDIEVIHKDIEGAFYHMSYELADGSGVVEI
                     ATTRPETMLGDTAIAVHPEDERYQALIGKKVILPLVNKQIPIIADEYVDMEFGTGVVK
                     ITPAHDPNDFEVGNRHDLPRVNVMDDDGTMNELAGKYAGMERFAARKAIVQDLKEIGR
                     LIKIDTMIHSVGHSERTGVVVEPRLSTQWFVKMAPLAKKAIDNQETDQAVEFFPPRFN
                     QTFLRWMENVHDWVISRQLWWGHQIPAWYHKETGEMYVGMEAPADSENWVQDPDVLDT
                     WFSSALWPFSTMGWPDTESEDYKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGERPF
                     ENVLIHGLIRDEQGRKMSKSLGNGIDPMEVIEKYGADALRWFLSNGSAPGQDVRFSYE
                     KMDASWNFINKIWNASRFVIMNIEGMTVEEIDLSGEKSVADRWILTRLNETIERVTEL
                     FDRFEFGEAGRQLYNFIWDDFCDWYIEMSKEVLYGDDAVSKQTTRSILVHTLDQILRL
                     LHPIMPFVTEEIWEHIPHQGNSLVVAEYPVVRPEFDDETASKGMEVLKELIRAVRNIR
                     SEVNTPLSKPITLLIKTNDAKIDQFLVENTSYIERFCNPEELTISSEITAPDLAMSAV
                     LTGAEIFLPLAGLINIEEEIKRLEKELEKWTSEVKRVQGKLSNERFVSNAPEEVVEAE
                     RAKEKDYLEKQTAVKERIESLRTIQ"
     gene            16381..17694
                     /locus_tag="ACG8LA_002115"
     CDS             16381..17694
                     /locus_tag="ACG8LA_002115"
                     /EC_number="6.3.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004326 - tetrahydrofolylpolyglutamate
                     synthase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008841 - dihydrofolate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="folylpolyglutamate synthase/dihydrofolate
                     synthase family protein"
                     /protein_id="HFQ0204399.1"
                     /translation="MTIEEAIEWIHSRLPFGSRPGLDRVEALLEVVGHPERKVKTIHI
                     AGTNGKGSTVAYLRSLLEEAGLTVGTFTSPYIETFNERIAINGKSIPDNDLIQLVKKY
                     QPLIKQLDQFEAVAGITEFETLTAMAFDYFLMKKVDVAIIEVGLGGLLDSTNVAVPML
                     TGITTIGLDHTEILGDTIEEIAAQKAGIIKQGVPVVTGNIAPEAFTVIQQTAKAKNAP
                     LYVYGENYKINYLHPDEMWGEVFEFFNEIGKIPQLTTPLLGQHQAENAGVAIELYFVY
                     CQLEKLPFREKDVLKGLKKSRWPGRMERLSNEPLVVLDGAHNTHAMNRLVENLKKEFK
                     GYQINILFSALRTKNVREMLERLQQVPNVHIYLTTFEHPKAIELSEVSDLASERVSIV
                     SLWQFGLADILEKMTNEDVLVVTGSLYFISEVRHLLIQLGGDHEV"
     gene            17684..18337
                     /locus_tag="ACG8LA_002116"
     CDS             17684..18337
                     /locus_tag="ACG8LA_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFQ0204400.1"
                     /translation="MKYNAVIFDMDGLLFDTELVYYEATQVVADKMGFPYDKDLYLKF
                     LGVSDEEVWANYHMIFSEFGKTSVQRFIDDSYQETLERFSQGAVQMKPGVLELLSFLE
                     EHQIPKVVASSNQRAVIELLLKKNNLFERFETIVSAENVQRAKPDPEIFLLANQKLGT
                     AKKETLILEDSQNGILAASAAEIPVVMVPDLLPPSQELIKKTAGVVSSLHEIPALLK"
     gene            18392..19084
                     /gene="radC"
                     /locus_tag="ACG8LA_002117"
     CDS             18392..19084
                     /gene="radC"
                     /locus_tag="ACG8LA_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HFQ0204401.1"
                     /translation="MGKRLIKEVPTSSLPRERMEIYGAEALSDQELLAILLRTGQHPY
                     SVMSIAGNLLKTFGGLASLRQATLHELEEIRGIGRVKAIEIKALIELGRRIQTDHERA
                     APPVRTSYELAQQLILEMKDHKQEHLVCIYLDTKNQVILKKTVFIGSLNQSVAHPREI
                     FHYAVRYCAARIVLAHNHPSGNVIPSQQDMNFTKRIQKCGEMMGITVLDHLIIGRKRY
                     FSLREEGMMEEK"
     gene            19234..19434
                     /locus_tag="ACG8LA_002118"
     CDS             19234..19434
                     /locus_tag="ACG8LA_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HFQ0204402.1"
                     /translation="MENGTVKWFNAEKGFGFISREDGSDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEESDRGPQAANVVKA"
BASE COUNT         6584 a         3294 c         4142 g         5518 t
ORIGIN      
        1 ggagtaaata aagcttatgc aaagaaaaag aaatccaatc acttgggttt ctttttcttt
       61 tattattatg atgaatcaag ctttctgttt ttgtcacgta tgttgtaatc tttacgaaag
      121 agtagagttg gctactcata atcaaccata cttcccatca tcgctaaata cgaaataaat
      181 cagcattcct acaccaatca aagcacaagc tgcaccaaga aaagggatga cattcccaaa
      241 gttatctgta ttcataagta tgccaccacc cacaaacaaa aagccgccag caatcaggtt
      301 tttcatttta ttcatctcct ttcttacgtt atagtatttc cttctttcaa tgagtatttt
      361 gaaagctatc ttattgtatg atgttcttct aggcctcttc tttattatac aggccatttt
      421 cgttatctca tagaaatatt cctttttatc tgaaaactat tgtataccgt atgacatttt
      481 tcttcatgaa gttgtaagta tattctcatt caaatgaaaa tttcatcata gaagagattg
      541 tatttctaaa ttcttaagag taaaatacga agtataactt ggatttggaa ggatgattgg
      601 atgaaagcta ttacgcctga tatgacaaca aaatttaaca aacagtttca agcaaatatc
      661 aaacagcagg cattgcagcg ggcagttgtg aagaacggaa ttactgcttc tgctgaaaat
      721 gtttcagcac atgtggagaa tacaccggta ttttctatag atttggctac ggggaaagtg
      781 gctaatcaaa tgcaatcggg gcgttgctgg atgtttgctg cactgaacac attccgtcat
      841 aagatgctga atcaattcca tttaaaagag tttgaattat cacaaaatta cacttttttc
      901 tgggataaat atgaaaaggc aaattatttc tatgaaaaca tcattgcaac aggaaaagag
      961 gcaatcgata gccggaaagt agctttctta ctcgctactc ctcaacaaga tggcggccaa
     1021 tgggatatga tcgtttcatt attccaaaaa tatggcgttg tgcctaaatc ggtgatgccg
     1081 gaaagtgcga atagttcaaa ttctcgagat ttgaataact acttgaacaa attactgcgt
     1141 aaagatgcag tagtgttacg gaaaatggtt gctcaaggag aaacattaga cgctattgaa
     1201 gaaaagaaag aagaaatgct agaaagcatt tataacttct tagctatctc attaggaaca
     1261 cctccaaaag aattcgattt tgagtaccgc gatgaagaaa agaactatca tcttgaccga
     1321 ggactgacac cacaaatttt ttatgataaa tacatcggtg taaaattaga tgattatgtt
     1381 agcgtgatca atgcaccaac aaaagacaaa ccattcaatc gttcttatac agtagagatg
     1441 ctaggaaatg tcgttggcgg gaaagaagtc aaatatctga atgttgatat ggaaactttc
     1501 aaaaaattag cgattgctca gcttgaagaa ggagaatctg tttggtttgg ttgtgatgta
     1561 ggtcaatctt ctactagaac tagtggcatc atggccttag atgcttattc aatggatgat
     1621 ctatttgata cggattttac aatgactaaa gctgaacgtt tagattttgg agaaagtctg
     1681 atgacccatg cgatggtatt gaccggtgtt gacttagtag acgggcaatc aacaaaatgg
     1741 aaagtcgaaa atagctgggg cgaaaaagtt ggaaagaatg gcttctttgt tatgagtgat
     1801 gcctggatgg acgaatatac gtaccaaatc gttgtaagaa aagatttatt gacgaaagag
     1861 caattaaatg cgttcaatga agaaccaatt gttctatctc cgtgggatcc aatgggtgct
     1921 ttagcataga cgagtatttc aatgaagagt atgtagtaaa gataaaaaga gctggcttaa
     1981 gccagctctt tttatcttta aagtccattc cctgtttttt atggtccctg tgctataatt
     2041 ctaaataaag gataaggatt ggaaataatc cttttatcat taaaaatatg atgacgaagt
     2101 agaataaaat tgggagtagg ggggaaagtc atggatatcc aaactgtttt atctgatctg
     2161 aaattaaatg gtaaagtgat tccagttgtt ggtggcgatg ttaatcagac ctatcgtata
     2221 aaaaccgaac atcgtgctta ttttttaaaa atccatccga atgtaaaaaa aggatttttt
     2281 gaagcagaag tagacggatt aaaagaactg tcagcattcg tacgtgtacc ggatacgtat
     2341 atgctaggtg aaacaagtga aggcgcttat ttgttaatgg aatggatcga gccgggaaaa
     2401 ggggatcaac gagatcttgc tgcagcttta gctaatctcc atcagcaaac agcgccacaa
     2461 tttggttttc gtaaagataa ctatttgggt acacttgttc agaaaaattc ttttgaagaa
     2521 gattggtgga cttttttctt taaagatcgg cttgaatccc agatttcttt ggcagaagaa
     2581 acgaatcgat ggaatgtaca gcgtcaagaa aagtatctgc gatttaaaga acgtgtattg
     2641 aaatcggttg aaccaaaaaa gatcactcca cgcctcttgc acggagacct gtggagtggt
     2701 aatgtgttct ttgaccagca agggcatcca gtttttgtcg acccagctgt ttcttatggg
     2761 aatcgggaac aagatattgc aatgagccag ttattcggtg gtttccgacc ggaattttta
     2821 gatgcttatc aaactatatt tccattagaa aagggatgga aagaccgact gccgatttac
     2881 cagttatatt atcttttggc acatttgaat atgtttggag aaagttacgg ttcccaagta
     2941 gatcaattac tagaaaattt ttaagaggag ggcgtgtttt tggcaaaaaa atataccaaa
     3001 aagcatgaag tttcatatta tgagtgtgac atcaaccaaa cgatgacatt tccttcgatg
     3061 ttaggagtag ttatcaaaac gtctgaagat caaagcgacc agttgggaag aggcagtgaa
     3121 ttcgtcaata gctttggact tacttgggtc atcacgaatt attccatgga gattaatcgt
     3181 ctccctagag tcggtgaagt aatctcagta acgactcaag ccatggagta caataagttt
     3241 ttctgttatc ggaacttctg gatccatgat gaagatggga aagaattagt caaaatagaa
     3301 tctgttttcg tattgatgga ttttgtgaat cgaaaaatga gcagtgttaa tgaagagatc
     3361 attgctcctt ttgagagtga gaagatcaag aaaatcaagc gtcaggaaaa aattgaaaag
     3421 attgattcgg gcttcatgtt gccatatcgt gttcgttttt atgatatcga tagtaatcag
     3481 catgttaata atgcgatgta ttttaattgg atcattgacg tattaggata tgactttttg
     3541 actacgcatg ttccagaaaa agtaattatt cgatttgata aagaagtaga gtacgggaat
     3601 gagatcgaaa gccattttga acaaatccct atcgaaaatg gtgtcaaaac aaaacatgaa
     3661 atccgaatgc aagaacagct gtattgtgaa gcaaatatta tatggaaaaa taaataaaaa
     3721 agaggttgtg acagaagggg gcaacttcaa gaaataagaa gaaatttacg aaaattgttt
     3781 ctcaaatttt tgtaaatttt cgacttagtt ttcgaagaag ctatttttgt cacagcctct
     3841 ctttttaagt ttagctatta gataatgatg tttagttttg gataaacgaa atcaattctt
     3901 cacccgacaa accatagttt acagcaatca atagttttaa acgtgctttt tgactattaa
     3961 tactgttaca gaaaataatc cccatttttt ctagttcttt tcccccgcct tcataatcat
     4021 aaacaggctc tgcgattcca ttgaaacaac gagaaacaag tactacaggg attttttgga
     4081 caagaagctt ttccaaagca gctaaggctt gtggagggag attccccgca cctaaagctt
     4141 cgattaccaa accgtctact ttcgtatggg cgatggcttc caataagtcc ccttgcatcc
     4201 cagcatatgc tttaacgatc gggatagtcc catctacagc ggaaatgtcc agtcgctttg
     4261 tttctaaaag ttcctgcaag aataaaattc gattcttagt tactaagccg atgggaccca
     4321 atgtaggtgt tcggaaagta gcaacatttg tggtatgggt ctttgtcacg tagcgtgcag
     4381 aatggatctc atcgttcatg accaccaaaa cccccttatc tagcgcttct tcacaacttg
     4441 cgacacgaat cgcactttca aaattataaa ggccgtcact tccaagttca ttacttgaac
     4501 gcattgcccc agtcaaaaca attggtaatt tgttgccaat cgttgtatca agaaaaaaag
     4561 cagtttcttc taatgtatct gtaccgtgtg tgatcaccac tccggatata cctgatgcat
     4621 aagcggacaa gatacgttct tttaatacca acatgtgaga aggcatgatg tgtggtgagg
     4681 gaagattgaa gatatcttca actaataatt ctacatgctt ggggattgtg atttctgcat
     4741 ctaataatgg gtttgccaca tcaggactaa caccgcccgt gagcatgttt tctttcatgg
     4801 cgatcgttcc gccggtgtgt agtacaagta tttttttcat tttacagact tccttacgaa
     4861 taattttgca tagccgttaa atcttattgt atactatata aaagagtttt gctatcagtg
     4921 aagaataacg aatagcctaa cttatcataa aaaagctgac cttattaaaa tggaaaagac
     4981 tcaaccttga cctcctaata caatggagta tctggttgag tttcttttac aagaaagcag
     5041 ccaaggaaat caatcacgaa ggtggccgga aatgatcaga atcggattaa catcgtttaa
     5101 agaacatgac aaattaactg gtaaaaagaa taacactctt tatgaatatg cagggtttct
     5161 acccttagtg gaattagata ctgcctatta tggaattccc cgaaagtcct cagttgagaa
     5221 ttggataagt gaagtacctg aatcatttcg ctttgtagtc aaagtctatc aaggaatcag
     5281 cggtcaagga gactggaagc cttattatca gaccgaagaa gagatgattg cgcatttttt
     5341 agatgttatg tcgccaatgg tagatgctgg aaagatgttt tgctttttag tccaattccc
     5401 ctcatcattc aaatgtacga aagaaaatgt ccagtacttg cgcaaactta gaaagtggtt
     5461 tgagggttat cctgtttcta tagaattgcg ggattattct tggtacagcg atgaatttct
     5521 tgaacgtaca agaaacttta tgtctagagc cgctttttct ttagccatca tcgatgagcc
     5581 acagttgctg aatacaacga ttccttttga tccatttgtc accaatccga actttgctct
     5641 ttttcgattc catggtagga atgcgcaagg atggcaagca aatgataaag agtggcgtaa
     5701 aaaaagaacg ttatatcgtt attcagaaaa agaactgcaa gaactagcac atgaagtcaa
     5761 agtagttgat tctaagacaa aagaggtagg tgtgattttt aataataatt ctggtggtga
     5821 tgcggctgaa aatgcattag cactgcaaaa aatattaaat atcaagccag atggactcaa
     5881 tccaacccaa atggatctgt tttaagggct tattttattc aagaaagggg cgaagtctat
     5941 gatcaaagct attttttttg atattgacgg aacattggtc accaatcgtt caaaagcgtt
     6001 ggaatcaaca aaacaagcaa ttgaatatgc tcggaaaaac ggcattttat gcggtgtagc
     6061 aacggggcgc agcccagtaa agatcaaaga aatcattgat gaattggaat tagatatgta
     6121 tgtcgtgtat aatggtcaac tggtttttac tgcagatcgc acgattatcg accacccttt
     6181 tgaacaaaaa gtattggaac atattgttga atttgcagat gagaaccatc gacaaatcgt
     6241 ttttggtgcg agaaatcggt tagatggatc aacgacgatg ctattaggac aatcgatttt
     6301 tatcaagcga ctagtcagct ttttaccgcg taaattcccg gtacgtctga tgaaaaaaat
     6361 cctccaggtt tttagccctc accgacaaaa ggatcgttat gaaacgttag agatattaaa
     6421 agaaccaatt tatcaatgta tattgctcag tccggagtca gaacagaaaa agttagaaca
     6481 tcgctttccc gagtgtacgt ttcagcgttc aaatacgtat actgtagata tcatcccaaa
     6541 aggtggttca aaattactag gcatccaagc tttcgcaaat gctgtcgaaa ttgaaatgga
     6601 agaaattatg gcattcggcg atcattacaa tgatatcgag atgctgaaag gtgtaggaat
     6661 tggagtggcc atggggaatg ctcagatcga agtaaaacat gctgcagact ttgtgactca
     6721 atcaaatgaa gaagatggga tatacgaagg actgaaacac ttcggtctga tttattagtc
     6781 aatgaaagaa ggaaaaaatc agtatggaag cagagacacc ttttcaaaaa gtagaaacat
     6841 tccacaaaac ttttgatcca agaagaccag agatacccac ggcttttaca gaaaatgaag
     6901 ctcatacacg tgctgcgttc aaaatagaag aacttgttga atttgttgca gctacttcac
     6961 ctaataaaga acaactgcat gaagctgtta tgctgctgca cgaagcatta gataaagcag
     7021 aagaaaaaat acttggtaaa acacagtggg gaagtgatcc gctggttgaa caagtagatg
     7081 cactgacaga tatcctttac ttatggttct ttttcattac taggaatagt gcctgatcga
     7141 atattcgaaa tcgtccatca ggcaaatatg gggaaattat ttccagatgg aaaacctcat
     7201 tatgaccctg taacaaataa agtgttgaaa cctgaaaact ggcagatgga atatgctcca
     7261 gaacctaaaa tcgcggcaga aatccaacgt cagattcaag aagcgattgc taagaagaaa
     7321 tccgctgata taggcatgtg cacaaatgaa aaagagtgat cagagtttca ctatttttgt
     7381 tatctttata cgatggaaaa acaaaagatt ttcgtttaag ttagtgaatg catgaaaata
     7441 gtatgctata atctagaata gatgtctttt gcacgagaga cgtattattt ggatttatgc
     7501 caagcagaac gccatctgtt gcataaaaga tgcatactga aaacggagga accataaatg
     7561 ggaaataatg ttatcatcgg aatcgtcatt gcaatcatta tagtcgccat tgtcgtcttt
     7621 ttggttagtt acttgatgaa gaaaaaaaac caagatcgat tggatgcctt agaaaaacgc
     7681 aaggaagaat tatttgactt gccagtgatt gaagaagtcg atgatgttaa aaaaatgcat
     7741 ctggttgggc aaagccaaaa tacctttcgt gaatggagtc aaaaatggaa tgacatatct
     7801 acttcctcgt tcgctgaact agaaagtcaa attttcgaag tggaaaacct caatgaaagt
     7861 tttcggttct taaaaggaaa aaaagcagtt gttgaagcag aagctacaat ggaccaaatg
     7921 gagaaacaag tgacggaaat ccgtgaaggt ctaaaggaat tgcgggaaac ggaagaacgc
     7981 aactcactag ctgttcagca ggcacttgac gtctatgaag aactgaaaga aaaagtcaga
     8041 gaagacgagc atgaatacgg accagctctt tttgaattgc aaaaacagat caaagtgatc
     8101 gaaaaagaat ttacgcagtt tgtgacttta aacacttctg gagaccctgt tgaagcccgc
     8161 gaggttttgg ataaagcaga aaaacatacg tatgaagtgg aagctctgat gaaaaaaatt
     8221 ccaccgctgt atgaggagct ccataccact ttccctgaac aacttgaaga aatcagtgat
     8281 acttacgaga aattgatgga agaacaatat gtattcccag aagaagatct tgctgaagat
     8341 atcgcaaaag taagtcgaag aattgaaaat tcattagcca atcttgaaaa aacagaagtt
     8401 gaaacggtcg aatttgaaaa ccgtgaaaca gctgatttga ttgattcgtt atatgatatc
     8461 ttagaacggg aaatggaagc tcagagatat gtaaaaacta accaatcaac gattgcagag
     8521 tatatcaaac atacaacaaa gaataaccgt caattattga ttgagctgga tcacacatct
     8581 caaagctata cattgaacca caatgaaatt ggccgtgtac gaggtttcca aaccgaagtg
     8641 gaagaaatgg aacgtcaaaa tgaacagatg attccacaga tccgtcaaca cgaaattcct
     8701 tattcagaag tgcgcacgtt ctataaaaca gtcttcaaag tcttagaaga tatcgaaaag
     8761 caacaagtag agatcgacga ctcattacat gaattgagaa aaggcgaaaa agaagcgcaa
     8821 gaaaagatcg atacattcga attcaaattg cgcagtttga aacgttttgt agaaaaacaa
     8881 cgtttgcctg gcttgccgaa tgattaccta gaattctttt ttgttgctac tgaccgtatt
     8941 gaagaactaa gtgttgtctt gaataaaatt cgagtaaaca tggaagaggt caatcgttta
     9001 gttgctctat gtgaagaaga tctagaatta ttagataaga agacacatga tttagtagat
     9061 gcagcagcat taacggagca aatgctccaa tatgcaaatc gttatcgtca tacacacgaa
     9121 gaagtgagag aagcaattga taaaagctac tatttattca ataaagaata tcactatcaa
     9181 gaagcattag acgaaatcgg tacagcatta gagcgagtag aacctggtgc tttcaaacgc
     9241 atcgaagatt tttattttaa tcatccagac ttagtataaa gcaaaaaagt tagtaaacca
     9301 gcaagagcaa gacggattat tgtcttgttc ttgtcttttt ttgtatattt gaaaattgaa
     9361 acaagtgaaa atttcacctg ctcttgaaag caccttggac aaccgttata atagaaaaga
     9421 atttcaaaaa agaggggttt cttatgatat attttgataa cagtgcaaca accccaatct
     9481 ttccgcaaag cttagatgca tatgtaaaaa ccagtcagcg gattattggg aatccatcaa
     9541 gcttgcatga tttaggcaat caagctaacc ggttgttgca gcaagcaaga aagcagatcg
     9601 ctgatttgat ccatgtagaa ccagaagaaa tctattttac ttcaggcgga acagaaggag
     9661 ataactgggt attaaaagga acgatgatcg aaaaaagaga atatgggaat catatgatca
     9721 tttcaggagt cgaacatccg gccgtcagcg agacagcaga acaattaaaa gaattaggaa
     9781 tcgaagtaag tatcgcccca gtggataaac gcggatttgt acgtgtcgac gaattgaaag
     9841 aattaataag aaaagagaca gtattagtct ctgttatggc tgtgaataat gaagtaggat
     9901 cgattcagcc catccaggaa atcagtgatc ttttggatga ttttcctaaa attcatttcc
     9961 atgtagatgc tgttcaggcg attggaaaag taccattctc gcaatggttg acagaaagag
    10021 ttgattttgc aacattttca gctcataaat tccatggccc acggggaact ggtttcattt
    10081 attggaaaaa gggtcgtcgt ttagcaccat tactgacagg tggagggcaa gaaagaaatc
    10141 agcgaagtgg gacagaaaat gttccaggta ttgtggctat ggttaaagct ttacgtttat
    10201 cattagagat aaaggaacaa aaacctgagc agacacaacg cttaaaagta gctctaatca
    10261 atgcgttgaa gacgtatgag aaagtgacga ttttttcaga aggaactgac tatgcaccgc
    10321 atattttatg ttttgctcta aaaggaattc gcggcgaagt tctcgtccat gccttagaag
    10381 aaaaacaaat atttgtttct actactagtg cctgctcctc acgtaaacat atggcaagca
    10441 gtacattgca cgcaatgcat gtaccaaatg atctggctac atctgctgtt cgaatcagct
    10501 tagatgaaaa caattcgctt gcagaagtcg agcaatttat gattattttc aagcagcttt
    10561 ataagaaatt ttctgcaatc aattaaaaga ggagtgttct tgtgaaatac agtgaaatta
    10621 tggtccgtta tggggaactt tcgacaaaag gaaagaatcg aaaaagcttt atcatgcaac
    10681 tagcacaaaa tgtcagacaa gctttgaaag actttccaga aatcaaaatc catgctgatc
    10741 gggaccggat gcatctttta ttgaatggcg cagacgggca gctagttatt ccaaaactag
    10801 caaaaatatt tgggatccaa aatttctctc caagtattcg tgtagaaaaa gatgtcgaag
    10861 ttttgaaaca agctgttcaa gacatcatga aagaaattta tactgggaaa gaaacattta
    10921 aaattatcgc taaaagaagc gatcaccaat ttgaattgac aagtaatgaa ttgaatcaaa
    10981 cattaggtaa tgctgttttt gatattttcc cgcatatcca agttcaaatg cgtcaaccag
    11041 atattccatt acgtgtagag attcggcgtg atggcgctta tctatcgtat gaaacgatca
    11101 agggagctgg aggattgccc gtaggaacaa gcggaaaagg aatgcttatg ctttctgggg
    11161 ggattgattc tcctgtagca gggtactttg ccatgaagcg gggagtggaa attgaagctg
    11221 ttcattttgc tagtccgccg tatacaagtg aacaagcact gcaaaaagca aaagatctaa
    11281 cagccaaact agcaccttat gtgggaacga tccattttat cgaagtgcca tttaccgaga
    11341 ttcaagaaga aatcaaaaag tcagtgccac aaggatattg gatgacaatt actcgtcgaa
    11401 tgatgttgcg tttgaccgat gaaattcgcc gtattcgtca tggtttagtc attttgaatg
    11461 gtgaatcatt aggtcaagtg gcttcacaaa ctttgcaaag tatggtggct atcaatgaag
    11521 taacgaatac gccaatcatt cggcctgtag cgacaatgga taaacttgaa atcattgaag
    11581 tagcagaaca gatcgataca tttaatcttt ctatccagcc ttttgaagat tgctgtacga
    11641 tttttgctcc tccacagcca aaaacacgcc ctcaactgga aaaggtccat caatatgaag
    11701 agcgtttagc aatagatgaa atgatccaac gagcactagc tggcttgaag atggaagaga
    11761 tacaagcaga atcgtctaat gaaaaaactg aagaattttc agaattgcta taagaggtta
    11821 tgaaaatagt gttttgacca gagtattaga gaaacaaaac gaaaaaatag ctccatgtat
    11881 tttaccgttt ttgaactaat gtcgaagatt agctgattga ataccattta tcaagaagtt
    11941 atggaaaagc cggttctttt ttactaactg aaaaataaaa ttttatttag agatcaagct
    12001 acagttgata aatgatataa aaaagagaat ttcccatgaa atagcgaggt tgtgacagaa
    12061 gtgggcagct tcaagaaata agaaggaatt tacgaaaatt gcttttcaaa tttttgtgaa
    12121 atttcggctt atttttcgaa gaagttactt ctggaacacc gtgtatcaga ggttgcgaaa
    12181 aagctgccct gcatcaagta ataagaacag ccaaacaaaa atagttcctc atattttacg
    12241 tttggttgag cttattaccg cagatgcaag cttttgaaca ccgttttatt tgtctcacac
    12301 ccttttcctt cctacttgta accttgctcc cgtgttagaa acatgttaca ctaaatatgt
    12361 gaaattatta acaaggagcg tcgttatgcg agaaaaaaca gatacactgc caaaagcaac
    12421 tgcgaaaaga ttacctttat atttacgcta cttgaagatg ctggatgact caggtataag
    12481 tagaatcaaa tcaaatgagt tcagcgaaat cacccaaatt ccttctgcaa cgatccgcag
    12541 agacttctcg caattaggcg agctaggcag aagcggatat ggctatgatg tcccttttct
    12601 tatcgatgta ttcaataata tccttaatac taaagaagaa aaacgaatcg cattagtagg
    12661 atatggaaat cttggcaaag cattgaaaca caacaatttt agaagaaatg aaaatctaaa
    12721 tatcgtgtgc gtctttgata atgatccagc actgatcaat cgagtaattg atggagaaat
    12781 gatctatccg attgatcgtt tcgcggagat agccaaagca aaaaatgtga cagtagcaat
    12841 ctctacggta ccaagtaaat attcacaatc tgctattgat gaaattgtca aaggaaatgt
    12901 aaccgctata cttaattttg cgcctgacag agtaactgtc ccagcttatg tcaatgttca
    12961 atacattgat ttgacaaccg agttgcagac gcttatttac tttgatgaga attactcaga
    13021 agttttttct taggaaaatt tgagtaggct tattgatctt gcgagaactc gtcgtaattc
    13081 tttcaaaaat tttttagtac taaatgaagt ggttttttca cgaccacttg ttgactaaaa
    13141 aaaaaaacca ttgtagaatg aagcataacg ctgaacaaga ggagtaactg gcacattcat
    13201 tcttagagag agaactatct gctgaaaggt tctcaatgac aaccagtgaa ggtagcttgg
    13261 gagtttctgt cttgaatgga gtagagatag acgagtcgtg atcgttaact cacttgagag
    13321 gcaataatga ttgattattg caatttaggt ggtaccgcgt aaatcatacg tcctagaata
    13381 cgaaagtatt ttaggacgtt ttttagttta aaggaggaaa acagcatgac ggaagaaaat
    13441 aacctatcaa caaaatataa tccgcaagaa gttgaagctg gacgttatca gcattggtta
    13501 gaacaagatt tgtttaaacc gagcggagat aaaaaagcaa aaccttattc aatcgtaatc
    13561 ccgcccccaa atgttactgg aaaacttcat ttagggcatg cttgggatac gaccttgcaa
    13621 gatatgctga ttcgtcaaaa gagaatgcaa ggatatgata ctttatggct gcctggtatg
    13681 gaccatgcag gaatcgcgac acaagcaaaa gtagaagcga agcttagaga gcaagggatt
    13741 tctcgttatg atctaggtcg tgaaaagttc atcgatcaag tgtgggaatg gaaagaagag
    13801 tatgcgagcc acatccgcga acagtgggct aaaatgggct tatctttaga ttacagtagg
    13861 gaacgtttta cattagatga tggattatct gaagcagtac gtaaagtttt tgttacctta
    13921 tacgaaaaag gtttgattta tcgtggtgaa tatatcatca actgggatcc tcaagcacga
    13981 acagctctat ctgatatcga agttattcat aaagatatcg aaggcgcctt ttatcatatg
    14041 agctatgaac tagcagatgg atcaggcgta gtagaaattg cgacaacccg tccagaaacg
    14101 atgttgggag atacggcgat tgctgttcat ccagaagacg agcgttatca agcgctcatc
    14161 ggcaaaaaag tgattctacc tttagtcaat aaacaaatcc caatcattgc agatgaatat
    14221 gtagatatgg aattcgggac aggtgtagta aaaatcactc cagcacatga tccaaacgac
    14281 tttgaggtag gtaatcgtca tgatcttcca cgcgtaaatg ttatggatga tgatggtacg
    14341 atgaatgaac tagcaggaaa atatgctgga atggaacgtt ttgctgctcg taaagcaatc
    14401 gtgcaagatc tgaaagaaat cggtcgattg attaaaatcg atacgatgat ccacagtgtg
    14461 ggtcattccg agcggacagg tgtcgttgtt gaacctcggc tgtctactca atggtttgta
    14521 aaaatggcgc cgttagcgaa aaaagccatt gataaccaag aaacagatca agcagtggaa
    14581 ttcttccctc caagattcaa tcaaacgttt ttacgttgga tggaaaatgt ccatgattgg
    14641 gtaatctcac gacaattatg gtggggacat caaattcctg catggtatca caaagaaaca
    14701 ggtgaaatgt atgtagggat ggaagcacca gcggatagtg aaaactgggt acaagatcct
    14761 gatgttttag acacttggtt tagttcagct ttgtggcctt tctcaacaat gggctggcca
    14821 gatacggaaa gcgaagatta taagcgatac ttccctacta gcactttagt aaccggttat
    14881 gacatcattt tcttctgggt aagcagaatg attttccaaa gcttggaatt tactggcgaa
    14941 cgtccatttg agaatgtctt gattcatgga ttgattcgtg acgaacaagg gcggaagatg
    15001 agtaaatcat taggtaatgg aatcgatccg atggaagtaa tcgaaaagta tggagcagat
    15061 gctctccgct ggttcttatc gaatggttct gcaccaggac aagatgtccg cttcagctat
    15121 gaaaaaatgg atgcttcttg gaactttatc aacaaaatct ggaatgcttc acgtttcgtt
    15181 atcatgaata tcgaaggaat gaccgtagaa gagatcgatt tatctggaga aaaatcagtg
    15241 gctgaccggt ggatccttac tcgtttgaat gaaacgatcg aacgagtaac tgagctattt
    15301 gatcgttttg aatttggtga agcaggtcga caactgtata actttatctg ggatgatttt
    15361 tgtgactggt acatcgaaat gagtaaagaa gtactttatg gagatgatgc tgtttcaaaa
    15421 caaaccaccc gtagcatctt agtccataca cttgatcaga tcctacgttt attgcatcca
    15481 atcatgccat tcgttacaga agaaatatgg gaacatattc ctcatcaggg aaattctcta
    15541 gtagtggcag aatatcctgt tgtacgtcca gagtttgatg atgaaacagc ttctaaaggg
    15601 atggaagtat tgaaagaatt gattcgagcc gttcgaaata ttcgttcaga agtgaataca
    15661 ccattgtcta aaccaattac gttgctaatt aaaacaaacg atgctaaaat cgatcaattt
    15721 ttagttgaaa atacaagcta tatcgaacgc ttctgtaatc ccgaagagtt gacgatatca
    15781 agtgagatca ctgcgccaga tctagcgatg tcagctgttc tgacaggtgc agaaatcttc
    15841 ttgccgttag caggattgat caatattgaa gaagaaatca aacgattaga aaaagaactg
    15901 gaaaagtgga caagcgaagt aaaacgtgtc caaggaaaac tttctaatga acgttttgtt
    15961 tctaacgcgc cggaagaagt agtagaggca gagcgtgcaa aagaaaaaga ttatttagag
    16021 aagcaaacgg ctgtcaaaga acgaatcgaa agtttgcgta ctattcaata agaatagaaa
    16081 aagagagtgt gaaatcagct agctattact aaaagctagc tgattgaaca tcgttacagg
    16141 aaagagtttg agcctcactc ttagcttcga ttcataagga gatgtgacat aaattttgtc
    16201 gcatctcttt tttagtctac tcttattatg taggagaagg agggaggtgg atcatgtatc
    16261 aagagtcaat aaagtagttg ataaaatcgt tcctctctct gtttcttttc tctttgtcat
    16321 acttttattt ttcttatgtg ttctatttgt tataataaaa gagaaatggg ggaattgttg
    16381 atgacgattg aagaagcaat agaatggatc catagtcgat taccatttgg ttcacgtcct
    16441 ggccttgacc gagtcgaagc tttattagaa gtggtagggc atccagagag aaaagtaaaa
    16501 acgatccata tcgctggaac aaacggaaaa ggttctactg tagcttattt gagaagccta
    16561 ttagaagagg ctgggctgac agtaggtaca tttacttcac cttatatcga aacgttcaat
    16621 gaacggatcg caatcaatgg caaaagcatt ccagacaatg atttgatcca gcttgtaaaa
    16681 aaatatcagc cactgatcaa acaacttgat caatttgaag cagtagctgg tattactgaa
    16741 ttcgagacat taacagcaat ggcatttgat tattttttga tgaagaaagt ggacgtagcg
    16801 attatcgaag ttggcttagg cggcttattg gattctacca atgtagctgt accaatgctg
    16861 acgggaataa caacgattgg acttgatcat accgaaatac ttggagatac aattgaagaa
    16921 atcgctgcac aaaaagctgg aatcatcaaa caaggcgttc cagtagtaac aggaaatatt
    16981 gccccagaag cttttactgt catccaacaa acagctaaag caaaaaatgc accgctttat
    17041 gtatacgggg aaaattataa aataaactat ctgcatcctg atgagatgtg gggagaagta
    17101 tttgaatttt ttaatgaaat aggaaagatc cctcaattaa ccactccgct tttagggcaa
    17161 catcaagctg aaaatgcagg agtagccatc gaattgtatt ttgtttactg tcaattggaa
    17221 aagctgcctt tccgagaaaa agatgttttg aagggattga agaaatctcg atggccagga
    17281 agaatggagc gtttgagtaa cgagccatta gttgttttag atggtgccca taatacgcat
    17341 gcaatgaacc ggcttgttga gaatttgaaa aaagaattca aaggatatca aatcaacatt
    17401 ttgttttccg ccttacgaac taaaaatgtt agagaaatgc tagaacgatt gcagcaagta
    17461 ccaaatgtcc atatttattt gacgaccttt gaacatccaa aagccatcga attaagtgaa
    17521 gtatcagatt tagcaagtga gagagtatca atcgtttcat tgtggcaatt cggattagca
    17581 gatatattgg aaaagatgac aaatgaagac gtattagttg tgaccggttc actttatttc
    17641 atttcagaag ttcgccattt attaatacaa ttaggaggag atcatgaagt ataatgcagt
    17701 gatttttgac atggatggtt tgctgttcga cacagagtta gtgtattacg aagccacaca
    17761 agtagtagca gacaagatgg gttttcctta tgataaagac ctgtatttaa aattcttagg
    17821 tgtttcagat gaagaagtat gggcgaatta tcatatgatt ttctcggaat ttggcaaaac
    17881 aagtgtacaa agattcatag atgattcata ccaggaaacg cttgaacgtt tttcgcaagg
    17941 agcggtacaa atgaagcccg gtgtgttgga actcctctct tttttagaag aacatcagat
    18001 tcccaaagtt gtcgcttcca gtaaccaacg agcagtcatt gaacttttat tgaagaagaa
    18061 caatctgttt gaacgatttg agacgattgt ttctgcagaa aatgttcaac gagcaaaacc
    18121 agacccagaa attttcttgt tagctaatca gaagctaggt acagcgaaga aagaaacatt
    18181 gattttagaa gattcacaaa atggtatttt agcagcttct gcggctgaga tcccggtagt
    18241 catggtacca gatctgcttc caccatccca agaattgatc aaaaaaacag ctggggttgt
    18301 ttcttcttta catgaaatcc ctgcattgtt aaaataaaaa tccatctctt ttcgtatctt
    18361 attttagata agatagaaag gagatgtttt tttgggaaaa cgattgatca aagaagtacc
    18421 tactagctct ttaccaaggg aacgtatgga aatttatggc gcggaagctt tatcggatca
    18481 ggagcttttg gcaatcttac tgcgtaccgg tcaacaccct tatagtgtga tgtcgattgc
    18541 tggaaatctg ttaaaaacgt ttggaggact ggcctcttta cgacaggcta ctttgcatga
    18601 gttagaagag attcgaggga taggacgcgt gaaagcaatc gaaatcaaag ccttgatcga
    18661 attaggtcga cgaattcaga cggatcatga aagagcggct ccaccggttc gtaccagcta
    18721 cgaattggcc cagcaattga ttctggaaat gaaagatcac aaacaagaac atttggtttg
    18781 tatttatttg gacacgaaga atcaagtgat cttaaaaaaa acagtgttca tcggttcgct
    18841 gaatcagtca gtcgctcatc ctagagaaat tttccattat gctgtacgtt attgtgcagc
    18901 aaggatcgtt ttagcgcata atcatccttc tggtaatgtt attccatcgc agcaggatat
    18961 gaattttacc aaaaggatac aaaagtgtgg agaaatgatg gggatcactg tactggacca
    19021 cttgatcatc ggacgcaaac gatattttag tttgagagaa gaaggaatga tggaagagaa
    19081 gtaagttgct ttcttgcaaa aaaaatgaag caagtgtaca attatattgt aattttgttt
    19141 gggaatagaa gttgaaacat ctgttgcacc tctatcgtac acgagcaatg ttacaattta
    19201 aattagtgct tttggcacga ggaggatatt attatggaaa acggaacagt aaaatggttc
    19261 aacgctgaaa aaggatttgg atttatctca cgtgaagatg gaagcgacgt attcgttcac
    19321 ttctcagcta tccaaggtga cggattcaaa acattagaag aaggtcaagc agtgactttc
    19381 gacgttgaag aatcagaccg cggcccacaa gctgcaaacg ttgtaaaagc ttaattttat
    19441 ctgtaaatca aattgatggt agacatcaat ttttacgaga gaacaaagcg agtaacaaaa
    19501 atacctgcca caagagacaa tttctcttgt ggcaggta
//
LOCUS       DAZKKZ010000056        19506 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.057, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000056 DAZKKZ010000000
VERSION     DAZKKZ010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19506)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19506)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19506
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.057"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(459..1088)
                     /gene="udk"
                     /locus_tag="ACG8LA_002119"
     CDS             complement(459..1088)
                     /gene="udk"
                     /locus_tag="ACG8LA_002119"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004849 - uridine kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HFQ0204403.1"
                     /translation="MTKSKPIIIGVTGGSGSGKTSVSRAIFNNFPDHSIMMLEQDSYY
                     KDQSHLSFEERLNTNYDHPFAFDNDLLIQHVGDLLNYKAIEKPVYDYVAHTRSQATII
                     QEPKEVIILEGILILEDERLRDLMDIKVYVDTDDDIRIIRRIKRDMEERGRTLDSVIE
                     QYLTVVKPMYHQFIEPTKRYADIIVPEGGENHVAIDLITTKVASFLNHK"
     gene            complement(1172..1867)
                     /locus_tag="ACG8LA_002120"
     CDS             complement(1172..1867)
                     /locus_tag="ACG8LA_002120"
                     /EC_number="3.1.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008253 - 5'-nucleotidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HFQ0204404.1"
                     /translation="MKYKTLLFDVDDTLLDFQLTEANALSALFAEQGITLTPEIETSY
                     KALNHHLWQEFEKGRLSREEIIGSRFGLLFQQFGKTVDSDQMEKRYRHYLNQGHDLVP
                     GSLEILKKVHPHADLYIVTNGVSHTQHRRLTDAGMLDYFKDIFVSEAVGAQKPMKEFF
                     DHVFSHIPNFDKKQTVIIGDSLTSDIKGGNMAGIDTIWFNRNKLPEIEEIQPTYRIDS
                     LEELYSLLEIEKD"
     gene            complement(1880..2596)
                     /locus_tag="ACG8LA_002121"
     CDS             complement(1880..2596)
                     /locus_tag="ACG8LA_002121"
                     /EC_number="5.4.99.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_function: GO:0140098 - catalytic activity, acting on
                     RNA [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA pseudouridine(516) synthase"
                     /protein_id="HFQ0204405.1"
                     /translation="MRLDKLIEEKLETTRKEMKRLFALKQVMIDGTVEFRQNRNVDSL
                     LHQIEVAGEHLETNESYYLLNKPEKAVTAVSDPEKTTVIDLIASADRFQPLYPVGRLD
                     RDTTGLLLITSNGQLGYEMLLPEKKVSKTYQVVVNERVTPADVTAFENGIVFADGYQC
                     KPADLKILKADKHQSTVLLTIQEGKFHQVKKMFLAQGKKVTALKRLSMGPLELDEQLG
                     VGEYRSLTLAEMKKLSIYFK"
     gene            2926..3531
                     /locus_tag="ACG8LA_002122"
     CDS             2926..3531
                     /locus_tag="ACG8LA_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0008097 - 5S rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L25/general stress protein
                     Ctc"
                     /protein_id="HFQ0204406.1"
                     /translation="MSVSLEVSKREVRPRSLRNKLRHEGKVPAVVYGYKVESTPISFD
                     GLTLSKLLREHGANTVITMDIDGQKVNTLVHKIQTNTFTNHFEHAEFLSVNMSEETEV
                     ETEVVLVGESVGAKSGGVLAQNLYTVVVSATPDKLPERIEVDVTNLELGDSITVADLP
                     KNDDYKFVTDSEEQIAAVVAQSEEESTGEGGEPEVIGSTEE"
     gene            3856..4179
                     /locus_tag="ACG8LA_002123"
     CDS             3856..4179
                     /locus_tag="ACG8LA_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HFQ0204407.1"
                     /translation="MFESFDSSRNRYASVGVVSSLPDELIDSIWFIIDLDLKGVIPLE
                     NILTFDLIENRGKVTMHFSQAGSNVEMDIDLPFAYSNQFPAQVYAYDDGTRETILLPS
                     EIRQY"
     gene            4361..5731
                     /locus_tag="ACG8LA_002124"
     CDS             4361..5731
                     /locus_tag="ACG8LA_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HFQ0204408.1"
                     /translation="MRDLTKGSPAKLILMFTVPLLIGNVFQQFYNMIDMIIVGQTLGK
                     NALAAVGATGSLTFLIIGFAQGLTAGLAIITAQRYGAKDYRGLKKSFAASVVISLVVT
                     VILTVLSLLFIRPMLQLMQTPPEILDQAQTFISIILLGIFASVSFNLLSNVIRALGDS
                     RTPLFFLIIAVIINVVLDLIFIIYFGMGVEGAAIATVIAQVSSSVLCLVYIKKKMPLL
                     QLRKKDFKFEKEEFAVHLNAALPMAFQSSIIAVGAIVLQAALNSLGTDVVAAQAAAGR
                     IDQFANQPMMSFGIAMATFTAQNYGAKEYGRILQGVRQTLLMSVGFSLLAGAIVIFFG
                     HFFVQLFVSPSETRVFELAQTYFNINGSLYWILAVLFILRYTLQGLGQSKIPTIAGMM
                     ELLMRSFAAIVLTGMWGYPGAAAASPLAWIGSVAVLLYSYMRSMKQLKHMGEEEHFTL
                     EHAEAR"
     gene            complement(5861..7162)
                     /locus_tag="ACG8LA_002125"
     CDS             complement(5861..7162)
                     /locus_tag="ACG8LA_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin family protein"
                     /protein_id="HFQ0204409.1"
                     /translation="MVINFIILFLMIAITSFFVASEFALVKIRRSRLEQLEKENVKNA
                     KLALHVTHHLDNYLSASQLGITLTGLIIGWVGEGSVAALLEPVIGKLPFSSAISSTIS
                     VALGFILVTYIDVVIGELLPKSYSIVNTEKVVLFVVKPLHYFYKVMFPFIWVLNHSAA
                     GLGKLLGVRLVSEGEETLSQEELTLVALNSYEKGELTKEEYHYLENVFEFDDTLAKDI
                     QVDRTSMQVFEASETVKEAIKASIEQGHTRYPVILESKDNVLGYVTLPDLIKQSYKDD
                     QLTVEQLIEEPIVTTETIPIKKLLTIMRKKGKHIAILKDEYGGTSGLVTIEDILEEIV
                     GEIRDETDLDEALIAEQSDGSYIISGKLTLDDFQRYFHVEIPEFEETNFTTLAGFASS
                     RYKEIKAGTIIEIASFRFTVLEYQHAHIDYFKVESTERKIE"
     gene            complement(7392..9383)
                     /locus_tag="ACG8LA_002126"
     CDS             complement(7392..9383)
                     /locus_tag="ACG8LA_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KUP/HAK/KT family potassium transporter"
                     /protein_id="HFQ0204410.1"
                     /translation="MATTHNTKKISMAGLLVAMGVVYGDIGTSPLYVMKSIVEDNGGL
                     SGINPDFVIGSVSLIFWTLTLLTTIKYVVIALNADNHGEGGIFSLYTLVRKGGKYLII
                     PAMIGGAALLADGVLTPAVTVTTAIEGLRGIPQFFDRFGNNQNVIVIITLVIIFVLFM
                     VQRFGTDIVGKAFGPIMFAWFTFLGVMGLMNFSQDWTVIRALNPYYAIQLLFSADNKL
                     GLFILGNIFLATTGAEALYSDLGHVGKRNIRLSWPYVKICLVINYFGQAAWLLNVYQN
                     PEAQQIKNLNPFFQMMPQSWIVIGVAFATVAAVIASQALITGSFTLVSEAIKLKLLPR
                     LKIMYPGNSIGQMYIPAVNLILWIACSLVVVTFRTSHHMEAAYGLSITVTMLMTTALL
                     YFYLIQNGHSRWLAYLVTFFFGAIEVVFFISSVVKFFRGGFVAVLIGLIILVVMFIWE
                     QGNIIRESSTEDVSLRDYIPQLRELRDDTSLPIYQTNVVFLVPDMAEDKVGRQFIYSI
                     LDKRPKRARVYWFVHVEVTDEPYTKEYQVDMMDTDFIVQVNLFLGFRVQQEINVYVRQ
                     VIHDLMKQGRLPKQPQRYSLTPGREVGDFQFVLIDEVVSNVTTLGKWQRQIMQAKLAI
                     KKIATSPETWFGLEYSEVKHETVPLIIGNTRKTWLKERL"
     gene            complement(9527..9793)
                     /locus_tag="ACG8LA_002127"
     CDS             complement(9527..9793)
                     /locus_tag="ACG8LA_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HFQ0204411.1"
                     /translation="MLNFLWSLFIGGILGLIAGAILGKEVPGGVSGNIIIGFLGSWLG
                     EFLLGPLGPELGGFYLIPALLGAIFCLALYSFVARRIRERPKKE"
     gene            complement(10303..12429)
                     /gene="pnp"
                     /locus_tag="ACG8LA_002128"
     CDS             complement(10303..12429)
                     /gene="pnp"
                     /locus_tag="ACG8LA_002128"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004654 - polyribonucleotide
                     nucleotidyltransferase activity [Evidence IEA];
                     GO_process: GO:0006402 - mRNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HFQ0204412.1"
                     /translation="MSEKQVFKTTWGGRPLQIEVGQLAKQANGAVLVRYGDTVVLSAA
                     VASKEAKDTDFFPLTINYEEKMYAAGKIPGGFIKREGRPSTEATLTARLIDRPIRPMF
                     AEGFRNEVQVTNIVMSVETDCSPAMAAMLGSSLALSISDIPFDGPIAGVEVGRVNGEY
                     VLNPTVEQAEQTDIELTVAGTKQAINMVESGAKEVSEEDMLGALLFGFDAIKELVAFQ
                     EEIVQAVGKEKMEVTLLQVDEVLKKEIFDASYATMKAAVMTEEKLAREDNIEQVKIDI
                     REAYAEKFAGHEDEDHLLKEVKQITEDLEKDVVRELITIDKIRPDGRKLDEIRPLSSE
                     VSLLPRVHGSGLFTRGQTQALSACTLAPLGEHQIIDGLGVEVSKRFIHHYNFPQFSVG
                     STGRAGSPGRREIGHGALGERALAQVIPSEEEFPYTIRLVAEVLESNGSSSQASICAG
                     TLALMDAGVPIKAPVAGIAMGLVSDGENYTILTDIQGLEDHLGDMDFKVAGTKDGITA
                     LQMDIKIQGITEQILTEALTQAKQARMEILEELTSTIAAPREELSQYAPKIEMIQIEP
                     AKIKDVIGKGGDTINGIIDETGVKIDIDQDGKVSIASADAEMIKKAIKIIEDLTKEVK
                     VGEVYLGKVVRIEKFGAFVNLIKGKDGLVHISQLANDRVNKVEDVVKLGDEILVKVTE
                     IDKQGRVNLSRKAMLNEDGSTKNEEK"
     gene            complement(12617..12886)
                     /gene="rpsO"
                     /locus_tag="ACG8LA_002129"
     CDS             complement(12617..12886)
                     /gene="rpsO"
                     /locus_tag="ACG8LA_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HFQ0204413.1"
                     /translation="MAISKERKNEIINEYARHEGDTGSPEVQIAVLTEEINHLNEHAR
                     VHKKDHHSYRGLMKKVGHRRNLLAYLRKTDVQRYRELIKRLGLRR"
     gene            13137..13700
                     /gene="def"
                     /locus_tag="ACG8LA_002130"
     CDS             13137..13700
                     /gene="def"
                     /locus_tag="ACG8LA_002130"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042586 - peptide deformylase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HFQ0204414.1"
                     /translation="MITMDDIIREGNPTLREVAKEVSLPLSEEDISLGKEMLEFLKNS
                     QDPIKAEELHLRGGVGLAAPQLDISKRIIAVHVPSPDPEADGPSLSTVMYNPKILSHS
                     VQDACLGEGEGCLSVDREVPGYVVRHAKITVSYYDMNGEKHKIRLKNYESIVVQHEID
                     HINGVMFYDHINDQNPFALKEGVLVIE"
     gene            complement(13953..14474)
                     /locus_tag="ACG8LA_002131"
     CDS             complement(13953..14474)
                     /locus_tag="ACG8LA_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HFQ0204415.1"
                     /translation="MIEGETRRKQIMQTLANTEKPVSASKFAKTFGVSRQIIVGDIAL
                     LRAAGKSIVATARGYILETEETNTGHISKIAVQHGKDQTEEELRLIVENGGEIIDVIV
                     EHPLYGELAGTLHIKTPQDIDSFMRRYQKSNATLLSELTGGIHLHTIRYPEKHMLKNI
                     KQKLAEAGILYEG"
     gene            complement(14477..15319)
                     /locus_tag="ACG8LA_002132"
     CDS             complement(14477..15319)
                     /locus_tag="ACG8LA_002132"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HFQ0204416.1"
                     /translation="MTEFKTEKEKMIAGELYFANDPELVADRMFARSQSQIINQAESA
                     ELRSQLLKETFGRTGKKIYMEPVINFDYGYNIFVGENFYANFNCTFLDVSTIEIGDNC
                     MFAPNVQLYTATHPLHPVKRNSGLEYAKPIKIGNNVWLGGGVIVTPGVTLGDNVVVGA
                     GSVVTKSFPDNVVIAGNPARIIKTVEEELTEESLETLRHKIDMIDRELVALLEKRMDT
                     VTKIGQVKKEENQAVYDAKREQQVLDKVVSLLKNKGYKETITDTYVDLMKHSREYQNK
                     MKEE"
     gene            complement(15312..16037)
                     /locus_tag="ACG8LA_002133"
     CDS             complement(15312..16037)
                     /locus_tag="ACG8LA_002133"
                     /EC_number="2.3.1.286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0034979 - NAD-dependent protein lysine
                     deacetylase activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_function: GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HFQ0204417.1"
                     /translation="MKQLTVDEAAKEILAYQQITFLTGAGVSTPSGVPDYRSLSGIYH
                     GMEQPEYLLSHQAMVNEPDKFYQFVKKIYHPEAKPNIIHLEIAHLAKEKNVWVVSQNI
                     DGLHAKAKSPQLVNFHGSLYQCHCRKCQQTVDWKEYLHSDKHQACGGQIRPDIVLYGE
                     GFQDGVMEQAAYAVSQAELIVIVGTSFQVHPFCDLVQFRQPSAKILVINQTPVYLAEP
                     YTFIQEDGAVVFKKIQELGADYD"
     gene            16213..16509
                     /locus_tag="ACG8LA_002134"
     CDS             16213..16509
                     /locus_tag="ACG8LA_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204418.1"
                     /translation="MLPFFIYWGVILACIAWLALSVYFSVFYLVRKENGNLWAFALFN
                     VIAAIVLAITLAVYRTWGWGITQYSSLIYLILAIYGVVVLLQAILGREPKKAAA"
     regulatory      16765..16939
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00168"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Lysine riboswitch is most abundant in Firmicutes
                     and Gammaproteobacteria where they are found upstream of a
                     number of genes involved in lysine biosynthesis, transport
                     and catabolism; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="lysine"
                     /db_xref="RFAM:RF00168"
     gene            17077..18669
                     /locus_tag="ACG8LA_002135"
     CDS             17077..18669
                     /locus_tag="ACG8LA_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327538.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015837 - amine transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HFQ0204419.1"
                     /translation="MKKNMVSVAVLFAFVFSLFSVGSLANADEKTPSDEFRVGMEAGY
                     APFNWSQQTDENNALPIQGQNSYAGGYDVQIAKKVADGLGKKLVIVQTKWDGLAPALQ
                     SGKIDAIIAGMSPTAERRKEIDFTDPYYESQLVVVVQKDSKYAKAKSLADLSGAKITA
                     QLNTFHYTVIDQIPDVQKQQAMDNFSAMRTALASGMIDGYVSERPEGVTATSVNKDLE
                     MLEFSGADGFQTNPEDVQISVGMRKGDPDIQKVNQILSGISNDERTKIMDQAVKDQPA
                     ATDSEEKPGIISDFTTIWKQYGNMFLRGAGLTLFIALIGTVVGTTLGLLIGVFRSVPE
                     SGNALTRFFQKIGNALLSIYVEVFRGTPMMVQAMVIFYGLALAFGISLNRTIAALFIV
                     SLNTGAYMTEIVRGGIFAVDEGQFEAAQAIGMTHGQTMRKVVIPQVLRNILPATGNEF
                     VINIKDTAVLSVIGVADLFFQGNSASGANFQFFQTFTIVGIIYLVMTFTITRILRAVE
                     KKIDGPSAYTKLEEIDNSNLQE"
     gene            18682..19422
                     /locus_tag="ACG8LA_002136"
     CDS             18682..19422
                     /locus_tag="ACG8LA_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HFQ0204420.1"
                     /translation="MNEKIIEIKHLRKSFGENEVLKDISVTVNKGEVVTIIGSSGSGK
                     STFLRCINLLEKPTGGEIIYNGENVLAPKYNLPKYRTNLGMVFQSFNLFNNMNVLENC
                     MSGQTTVLKRDKETAKKVAIENLEKVGMDRYIEAKPAQLSGGQKQRVAIARALSMNPD
                     VLLFDEPTSALDPEMVGEVLNTIKDLAHTGLTMLIVTHEMEFAKDVSDRVIFMDKGVI
                     AEEGTPEDIFVHPKEERTKEFLSRILNA"
BASE COUNT         5579 a         4002 c         3702 g         6223 t
ORIGIN      
        1 gggggtgcga caaaagagct tcttcaaaaa aataagtcga aatctcacac aaattcgaga
       61 aataattttc gtaagtttct tcttatttat tgcatctgac cacttctgtt acaacctctc
      121 gttaaacggt gttcaaaagc ttgcatctac gataataagc ccaacccaac gaaaaacgtg
      181 aggagctgtt ttatttggat gctcttatcg cttgatgcaa agacagcttt tttacaacct
      241 ctacttcacg gtgctcaatc agctgacctt cggtattagc tcaaaaaacg gtaaaatata
      301 aacagctatt ttccgtttct tctttttaat acttaggtca agatgctgtt ttcacaacct
      361 cttgttataa ataaaaaaac agttggctgg tgactgttca aaaagcagaa tccttgcttt
      421 tcaaacggtc gcagtccgtt caactgtttc gctgcgcact atttatggtt taagaaacta
      481 gctacttttg ttgtaatcaa atcaatagca acgtggtttt ctccgccttc tggaacaatg
      541 atatccgcat agcgcttcgt tggttcgata aattgatgat acatcggttt aacaactgtc
      601 aaatattgtt cgatcacgga gtccaatgtg cgtccccgtt cttccatatc ccgtttgata
      661 cgacgaatga tacgaatgtc atcatctgta tctacgtata ctttgatatc catcaagtca
      721 cgcagacgtt cgtcttctaa aatcaggatt ccttctagaa tgatcacttc ttttggttcc
      781 tgaatgatcg ttgcctgact tcttgtatgc gctacatagt catacacggg tttttcaatg
      841 gctttatagt tcagtaagtc gcctacatgc tgaatcagca gatcattatc aaaggcaaat
      901 gggtgatcgt aatttgtgtt caatcgttct tcaaaactca aatggctctg atccttgtaa
      961 taagaatctt gttcaagcat catgatggaa tggtccggga agttgttgaa aatcgcacgg
     1021 ctgacacttg tctttccgct tccggatcca cccgtcacac caatgataat tggcttgctt
     1081 tttgtcattg actaaaacct ctttcgtatc cgttttttca ttctaatcta ttatagcgaa
     1141 aaaacacgaa aatgctatat ttttctgaaa attaatcctt ttcaatttcc aataatgaat
     1201 aaagttcctc taatgaatcg attcgataag taggctggat ttcttcgatt tctggtaatt
     1261 tatttctatt gaaccaaatc gtatcgatcc ctgccatatt tcctcctttg atatcagaag
     1321 tcaaagaatc accaatgatc acagtttgct ttttatcaaa attaggaatg tgggaaaaga
     1381 catgatcaaa aaattctttc atcggctttt gcgctccgac agcttctgag acaaagatat
     1441 ccttgaagta atcaagcatt cctgcatctg ttaatcgccg atgttgcgtg tgcgacacac
     1501 cgttcgtcac aatataaaga tcagcatgcg gatggacctt tttcaggatt tctagacttc
     1561 ctggaacaag atcatgacct tggttcaagt agtggcggta gcgtttttcc atttgatcac
     1621 tatctactgt tttcccaaat tgctggaaaa gtaacccaaa acgactgcct attatttctt
     1681 ctcgtgatag tctgcctttt tcaaactcct gccataaatg atgattcaaa gccttatagc
     1741 tggtttcgat ttctggtgtc aatgtgattc cttgttctgc aaacaaagca cttaaagcat
     1801 tggcttcagt taattgaaaa tctaacaatg tatcatctac atcgaacaat aaagttttat
     1861 atttcatctt tttgacctcc tatttaaaat aaatacttaa ctttttcatc tctgctaatg
     1921 tcaacgatcg atactcgcct actcctagct gttcatctaa ttccaatggt cccatgctta
     1981 gccgtttcaa tgcggtcact ttctttcctt gggctaagaa catctttttg acttgatgga
     2041 attttccttc ttggatcgtc aataaaaccg tactttggtg cttgtctgct ttgagtattt
     2101 ttaaatcagc cggcttacat tgatacccat cagcgaatac gattccattt tcaaatgctg
     2161 ttacgtctgc cggtgtcacc ctttcgttca caactacttg ataagtcttt gaaacctttt
     2221 tttctggaag tagcatttca tatcccaatt gtccattcga agtgatcagc aatagtcctg
     2281 ttgtatctct atctagtctt cccactggat ataatggttg gaaacgatcg gcacttgcaa
     2341 tcagatcgat tactgtcgtc ttttctggat ctgatacagc tgtaacagct ttttcaggtt
     2401 tattgagaag ataataggac tcatttgttt ctaagtgttc acctgctact tcgatttgat
     2461 gcagtaaact atctacattt cgattttgtc gaaattcgac tgtgccatct atcatcactt
     2521 gcttcaaagc aaacagccgc ttcatttcct tgcgtgtcgt ttctaatttt tcttctatta
     2581 atttatctaa acgcatgctg tttcctttct tattactact aattaattat accttgaata
     2641 ttcttgcttg caaatacatc atcatagtta ttccttgact taattaacag ttcacgttac
     2701 ggttaaatag taaagtgaat tggatttctc atacacagcg taatgacctg gtggagaaaa
     2761 gttgaatcct gactttctaa ggggagatgc gcgcatctct ccttttgcgc ttttttaagc
     2821 gccctgcctt cgatgatgtg cacgagatta gcctttagaa ttcacttaaa taaaatctgt
     2881 ccgttaccaa agcagacagt cacattttaa ggaggaattt tggttatgtc agtatcatta
     2941 gaagtaagta aaagagaagt acgtccccgt tcattaagaa acaaacttcg tcacgaaggg
     3001 aaagttccag ctgttgttta tgggtataaa gtagaaagta cccctatctc attcgatggt
     3061 ttgacactaa gcaaattgtt gcgtgaacat ggagcgaaca cagtcatcac gatggacatc
     3121 gatggacaaa aagtcaatac attggttcac aagatccaaa cgaacacttt taccaatcat
     3181 ttcgaacatg cagaatttct atctgtaaac atgtcggaag aaacagaagt cgaaacagaa
     3241 gtcgttcttg ttggcgaatc agtgggtgct aaatctggtg gagtgttagc tcaaaacttg
     3301 tatacagtag tcgtatctgc tacaccagac aaattgcctg aacgaattga agttgacgtg
     3361 acaaacttgg aattaggtga ttctattaca gtagccgatc ttccaaaaaa cgacgattac
     3421 aaattcgtga ccgacagtga agagcaaatc gctgctgtag tcgctcaaag tgaagaagaa
     3481 agcacaggtg aaggtggcga accagaagtg atcggttcaa cagaagaata atactgaaac
     3541 aatcaggtgg tgttagaagc ggcgggtcag cagcttttaa cacgcctttt ttatttctaa
     3601 tcgtttattt tcatatgggg cttccacttt tgtaaatggc tttacaaacg aaaaatccta
     3661 atttaccaag cttttcctcg catactttta tcgtaccttt ataaaaattt atactttgaa
     3721 aaaaagtatt caattattgt tgcatttttc ctgattcttt attagaatga accctcgttg
     3781 aagtaagtat ttctagttta tcctaggatt aattataaaa ataaaacatt cgttgattcg
     3841 aaggaggtta aacagatgtt tgaaagtttt gatagcagcc gcaaccgtta cgcttcagtt
     3901 ggtgtcgtat caagtttgcc agatgaattg attgacagta tatggtttat tattgaccta
     3961 gatcttaagg gagtcattcc attagaaaat atattaacct ttgatttgat cgaaaatcgt
     4021 ggaaaagtga cgatgcattt ttctcaagca ggaagcaatg tggaaatgga tattgatttg
     4081 ccgtttgcct attcgaacca atttcctgct caagtatacg cctatgatga cggtacgaga
     4141 gaaacgatcc ttttaccaag tgagattaga caatattaag gtgatagata aacgtggatg
     4201 tcccttattt tacagaccag gccaagttgt tgattctttg actcaattct tggcttcttt
     4261 ttatggagtt tcataaatta tcattgattt ctaattggta ttctcaggat aaacgctata
     4321 tactactaac taaattttaa agatataagg agtttaaaag atgcgcgatt taacaaaagg
     4381 aagccccgct aaactgattt tgatgttcac tgttccttta ctgatcggaa atgtttttca
     4441 gcagttctac aatatgatcg atatgatcat cgtgggtcag acgctaggta aaaatgcgct
     4501 ggcagcggtt ggtgcaactg gaagcctgac atttttgatc attggctttg cccaaggttt
     4561 aacagctggt ttagccatta ttaccgcaca acgttacggt gcaaaagatt atcggggtct
     4621 gaagaaaagt tttgctgcta gtgttgtcat tagtcttgtc gtcactgtga ttttaactgt
     4681 cctaagtctc ctgtttattc gtccgatgct tcaattgatg caaactcctc ctgaaatact
     4741 tgatcaagca caaacattta tttcaattat tttattaggg atctttgcat cagtcagttt
     4801 caatttgctt tctaatgtca ttcgcgcact tggtgacagc cgcacaccac tattctttct
     4861 gatcattgcg gtcatcatca acgtcgtact tgatttgatc tttattatct attttggcat
     4921 gggtgtggaa ggtgcagcta ttgctacagt aatcgcacaa gtttcttcca gcgtactgtg
     4981 tctagtgtat atcaagaaaa aaatgccttt gttacagtta cgcaaaaaag atttcaaatt
     5041 tgaaaaagaa gagtttgctg tacacctaaa tgctgctttg ccaatggcgt ttcaatcttc
     5101 gatcatcgct gttggtgcta tcgtgttaca agcagcacta aatagtctag ggacagatgt
     5161 cgtagctgct caagccgctg ctggtcgtat cgaccaattt gcaaatcagc cgatgatgtc
     5221 atttggtatt gcaatggcaa ctttcactgc acaaaactat ggtgcgaaag aatatggccg
     5281 aatcttgcaa ggggtacgtc aaactttact gatgagtgtc ggatttagtc tcttagcagg
     5341 tgctatcgtc attttcttcg gtcatttctt tgttcaattg tttgttagcc catcagaaac
     5401 acgtgtattt gaattagcac aaacctactt caatatcaat gggtctcttt actggatctt
     5461 agcagtcctg ttcattttac gctacacact tcaagggctt ggacaaagca agatccctac
     5521 gatcgccggt atgatggaat tgcttatgcg ttcttttgca gctatcgttc ttacaggaat
     5581 gtggggatac ccaggagcag cagcagcttc tcctttagct tggatcggtt ctgttgccgt
     5641 gttgctttac tcttatatgc gttcgatgaa acaattgaaa cacatgggtg aagaggaaca
     5701 tttcacatta gaacatgcag aagcaagata gccttgatta aaagaaatcg ttgcggctaa
     5761 aaatgaaaac ttttattgaa aatatcttct tcgtttaccg aaaacaggtt ttttagataa
     5821 caaaaaggct gtgacaaaaa atgtcacagc cttttttctt ttattctatt tttctttccg
     5881 tggactctac tttgaaataa tcgatatgtg catgctggta ttctaatacc gtgaaacgga
     5941 atgatgcaat ctcaatgatt gttcctgctt ttatttcttt atatcggcta gaagcaaagc
     6001 ccgcaagtgt agtaaaattc gtttcttcaa actctggaat ctctacatga aaataacgct
     6061 ggaaatcatc taatgttagt ttgccggaga tgatataaga gccatctgac tgttccgcta
     6121 tcaatgcttc gtccaaatct gtctcatctc ggatttcccc gacgatttct tctaaaatat
     6181 cttcaatcgt cactaagccg cttgtccctc cgtattcatc ttttaagata gcaatatgct
     6241 ttcccttttt tcgcatgatc gtcaataatt tttttatagg gatcgtttca gttgttacga
     6301 tcggctcttc aatcaactgt tctactgtca gctggtcatc tttataagat tgcttgatca
     6361 aatctggcaa ggtgacataa cctaaaacat tgtcttttga ttctaagata accggatagc
     6421 gagtatgtcc ttgttcaatc gaagctttta tcgcttcttt gacggtttct gaagcttcga
     6481 atacttgcat ggacgtacgg tctacttgta tatcttttgc caaggtatca tcaaattcaa
     6541 acacgttttc caaataatga tattcttctt tggtcaactc tcctttttca taagaattca
     6601 atgcgactaa tgtcagctct tcttgagaca atgtctcttc tccttcagat acgagacgca
     6661 cacctaatag cttccctagc cctgcagctg aatgattcaa tacccaaata aaaggaaaca
     6721 ttactttata aaaataatga agtggtttaa ctacgaacaa gacgaccttc tccgtattga
     6781 cgatactata gctcttagga agcagttcgc caataaccac atcgatatac gtaactaaaa
     6841 taaatcccag cgccacagag attgtactgc taatagccga actaaaaggt agtttaccga
     6901 tcactggttc tagtaaagcc gcgacagatc cttcaccgac ccacccgatg atcaaaccgg
     6961 ttagcgtaat tcctaattga ctagctgata aatagttatc taaatggtgt gtaacatgaa
     7021 gagctagctt ggcgttcttt acattttcct tttctagttg ttccaatctt gatcgtctga
     7081 ttttcactaa agcaaattca cttgctacaa aaaatgaagt aattgcaatc atcaaaaata
     7141 aaataatgaa attgataacc atattctccc gcctttctct ttttctattg tacccttttt
     7201 ctacaaaaag attgaaaata atgcgtattc atatttagga ataaaaaagg agatgcggca
     7261 tttttcagcc acatctcctt atcacttcaa aatcattgcg ttacttgttg ctaaacagct
     7321 ttttcatgac ctctgataaa cggtgttcaa gtagctgaca ttcgacatta gttcaggtca
     7381 aagcgctact ttcacaaccg ctctttcaac catgttttcc gagtatttcc aatgataagc
     7441 ggaacagttt catgttttac ttcgctgtac tctagcccaa accatgtttc tggcgaggta
     7501 gcgatttttt tgattgccag ttttgcctgc atgatttgac gttgccattt tcctagagtt
     7561 gtcacattgg aaactacttc atcaatcagg acaaattgga aatcgccaac ttctcgccct
     7621 ggtgtcagag agtatctttg tggctgtttt ggcaaacggc cttgtttcat caaatcatgg
     7681 atgacttggc gaacatatac gttgatttcc tgttggaccc tgaaacctaa gaacagattc
     7741 acttggacaa taaaatcagt gtccatcata tctacttgat attctttcgt atatggctca
     7801 tccgtcactt ccacatgaac aaaccaatag actcgtgctc ttttaggccg tttatctaaa
     7861 atcgaataga tgaactgtcg gccaacttta tcttcagcca tatcaggaac caagaagacc
     7921 acatttgtct gatagattgg taaagaagta tcatcacgta attctctaag ctgcgggata
     7981 taatctctca aagacacatc ctcggttgac gattcgcgaa taatgttccc ttgttcccaa
     8041 ataaacatca cgactaagat gatcaaacca atcagaacgg ctacaaaacc gcctcggaag
     8101 aatttgacaa cacttgagat aaagaaaacg acttctatcg caccgaagaa aaaggtaact
     8161 aaatatgcaa gccaacgaga atgcccattt tggataagat aaaagtaaag cagtgctgtt
     8221 gtcatcaaca tcgtcacagt gatcgataga ccgtaagcag cttccatatg atgagacgtt
     8281 cggaatgtga caaccactag agaacaggcg atccataaaa tcagattgac tgctgggata
     8341 tacatttgcc cgatactgtt cccaggatac atgatcttta accgaggcag cagtttcaac
     8401 ttgattgctt ctgaaactag cgtaaacgaa cctgtaatca atgcttgcga agcaatgact
     8461 gcagcgactg ttgcaaaagc aacgccgatc acgatccaac tttgaggcat catttggaag
     8521 aatggattca ggttcttgat ttgctgtgct tcagggtttt gataaacatt caacaaccac
     8581 gcagcctgcc caaaataatt gataaccaaa caaattttga cgtaaggcca gctcagacga
     8641 atatttcgtt tgccgacatg tccaagatcg gaataaagcg cctctgcacc tgtcgtagcc
     8701 aggaaaatat ttccaagaat gaacaagcct aatttgttat ctgcactaaa aagcagctgg
     8761 atagcataat aaggattcag tgcacggata actgtccagt cttgactgaa gttcattaat
     8821 cccattacgc ctaaaaaagt aaaccaagcg aacatgattg gtccgaatgc ttttccgaca
     8881 atatctgtac caaagcgttg gaccatgaat aaaacaaaaa taataactaa agtgataatg
     8941 acgatcacgt tctggttatt accgaaccgg tcaaaaaact gcggaattcc tcgcaagcct
     9001 tcaatcgcag tcgttaccgt cacagcaggg gtcaataccc catctgctag taaggcagct
     9061 cctccgatca ttgcaggaat gatcaaatat ttcccacctt ttcggacaag tgtgtagagt
     9121 gagaaaattc caccttcacc atggttatct gcattcaatg caatcacgac atatttgatt
     9181 gttgtcagta gagtcaatgt ccaaaaaatc aatgagactg atccgataac aaaatcagga
     9241 ttgattcctg acaatccgcc attatcttca acaatcgatt tcataacgta aagcggactt
     9301 gtcccgatgt ctccgtagac gactcccatc gctacaagca ggccagccat tgatatcttt
     9361 ttggtattgt gcgttgttgc cacgtttttc cctcatttct tgttatatgg atatccttta
     9421 ggtaagcttg aatgatagat gatattctta tccatgacac ccgctttcct aaattgcttc
     9481 taattatcca agtaacacac tgaagtgtca acttatttga ataaaattat tctttctttg
     9541 gacgttctct gatacgtctt gccacaaatg aataaagagc aaggcaaaaa attgcaccca
     9601 ataatgctgg tatcaaataa aaaccgccga gttccggtcc cagtggtcct agtaaaaatt
     9661 cgccgagcca actacctaaa aaaccgataa tgatatttcc agatacgcct cccgggactt
     9721 cctttcctaa aattgcgcca gctatcaaac ctaatatacc gccgataaat aacgaccata
     9781 aaaaattcag catctccttt ccctccttta tccatatttc tcacttttat tttacgcttt
     9841 attcagaagg actccaaaaa tatgcgccaa gaaactccag aaaaaaagaa gttgtaacaa
     9901 aagtgttcag cttatttccg tagaagctgc ttctggaaca ccgtgaatca gaggttgtga
     9961 aatcagcggt ttgacctgag tattagagaa acaaacggaa aaatagttcc tcatattttg
    10021 ccgttttttg agctaatatc gagggacagc tgattgaaca tcgtttattg gagaggttgt
    10081 aaaaaagctg ttctgcatca agtaataaga acagccaagt aaaaacagct cctaatgttt
    10141 ttaacttggc tggacttatt accgcagatg caagcttttg aacaccgttt attcgaaaaa
    10201 aaaggactgt gacacggctt ttgtcacagt cccctttttt cgaataatta ttgtccccct
    10261 gtcaccttca cgatcacaag tacattattc ctatgaatta aattattttt cttcattttt
    10321 cgttgaacca tcttcgttca acattgcttt tcttgacaga tttacgcgtc cttgtttatc
    10381 gatttcagtt actttcacaa ggatctcatc acctagttta acaacatctt cgactttatt
    10441 gacacgatcg tttgctaatt gggaaatatg gacaagtcca tcttttcctt tgatcaagtt
    10501 gacgaatgca ccgaattttt cgatacggac aactttccct agataaactt caccaacttt
    10561 gacttctttg gtcaaatctt cgatgatctt gatagctttt ttgatcattt ctgcatcagc
    10621 tgaagcaata cttacttttc catcttgatc gatatcgatt ttcacaccag tttcatcgat
    10681 gattccgttg atcgtatcgc cgcctttacc gataacatct ttgattttag caggttcgat
    10741 ctggatcatt tcgatttttg gtgcatattg gcttaattct tcacgtggag cagcaatcgt
    10801 tgaagtcaat tcttctaaga tttccatacg tgcttgtttt gcttgagtta atgcttcagt
    10861 taggatttgt tctgtgattc cttgaatctt gatatccatc tgtaaagcag tgataccatc
    10921 ttttgtaccg gcaactttaa agtccatatc gccaagatga tcttccagcc cttggatatc
    10981 agttaggatc gtatagtttt caccatcaga aacaagtccc atcgcaatac cggcgactgg
    11041 cgctttgatt ggtacacctg catccatcaa tgctaatgtg ccagcacaga tacttgcttg
    11101 ggaagaagaa ccatttgatt ccaatacttc tgctactaaa cggatcgtat aaggaaattc
    11161 ttcttctgaa gggattactt gtgctaacgc acgttcacct aatgcgccat gtccgatttc
    11221 ccgacgccct ggagagcctg cacgtcctgt agaaccaaca gaaaattgag ggaaattgta
    11281 gtggtggatg aatcgtttgc tgacttccac ccctaaacca tcaatgattt ggtgctctcc
    11341 tagaggtgcg agtgtacaag ctgataaagc ttgtgtttgt cctcgtgtga acaaacctga
    11401 tccatgtaca cgtggcaata agctgacctc tgatgacaat ggacggattt catccaattt
    11461 acgcccgtca ggacggatct tatcgatggt gatcaattca cgtacgacat ctttttcaag
    11521 atcttctgtg atttgtttaa cttctttcaa caagtgatct tcatcttcat gacctgcaaa
    11581 tttctcagca taagcttcgc ggatatcgat cttcacctgc tcgatattat cttcgcgagc
    11641 aagtttttct tcagtcatta ctgctgcttt cattgtagcg taagaagcat caaagatttc
    11701 ttttttcaat acttcatcaa cttgcagtaa agtcacttcc attttttctt tccctactgc
    11761 ttgaacgatt tcttcttgga aagcaactaa ctctttgata gcgtcaaaac caaacagcaa
    11821 tgcaccaagc atgtcttctt ctgaaacttc tttcgcgccg ctttcaacca tattgatggc
    11881 ttgtttcgtt ccggcaacag tcaattcgat atctgtttgt tctgcttgtt ctactgttgg
    11941 attcaagacg tactcgccat ttacacgacc aacttctacg cctgcgattg ggccgtcaaa
    12001 tgggatatct gagattgata gtgctaaaga agaacctagc attgctgcca tagctggcga
    12061 gcagtctgtt tctacactca tcacgatgtt cgttacttgg acttcattac ggaagccttc
    12121 tgcaaacatc gggcgaattg gacggtcgat caaacgggca gtcaatgttg cttccgtact
    12181 tggacggcct tctcgtttga tgaaacctcc agggattttc cctgctgcat acattttttc
    12241 ttcataattg atcgttaatg ggaaaaagtc tgtatctttt gcttctttag aggccacagc
    12301 tgcacttaag actactgtat ctccataacg gactaaaacg gctccgtttg cttgttttgc
    12361 tagctgaccg acttcgattt gtaagggacg gccgccccat gtcgttttga atacttgttt
    12421 ttctgacata acttctcctt ttccttctcg tgaaagcaag acgctactaa acaaatgaaa
    12481 actgccgaaa gccgtctttt gagcagcttt catttggtta gtaggagtcc atctagcttg
    12541 atcacggaat tttacttaat tgatatacga gtaaaaaaag tgagattcat gtgaatccca
    12601 ctctttttga ctaaaattaa cgacgcaagc ctaaacgttt gatcaattcg cggtaacgtt
    12661 gaacgtcagt tttacgtaag taagctaaca agttacggcg gtgaccaact tttttcatta
    12721 ggccgcggta tgaatgatgg tcttttttgt gcacgcgtgc atgttcattc aagtggttga
    12781 tttcttcagt taatacagcg atttgtactt ctggagaacc agtatcccct tcatggcgag
    12841 cgtattcgtt gatgatttca ttcttgcgtt cttttgaaat tgccatttct ttcacctctt
    12901 tcgattattc ccctgcgact gagtaaaacg ttggtgattc gcttaaccaa gtggcaggtc
    12961 atgtgcctag agcacacagc tatactttac ctgaaaccgg gttgaaaatc aagtagttaa
    13021 tcattaagaa aaggtagttt tcaaacaatc ttactactac ttttccattt ttgtggtaaa
    13081 ctataatgcg aaaatagact tgaaacacag tcttttaaga aaggggtaca tattccatga
    13141 ttacaatgga tgatatcatt cgtgaaggaa atccgacctt acgcgaagtt gcaaaagaag
    13201 tttctcttcc attaagcgaa gaagatatct ctttaggaaa agagatgctt gagttcttaa
    13261 aaaacagcca agatccaatc aaagctgaag aactacactt acgaggcggt gttggcttag
    13321 ctgctcctca attagatatt tctaaaagaa tcattgctgt tcacgtacca agtcctgacc
    13381 cagaggcaga tggaccttct ctaagtactg ttatgtataa tcctaaaatt ttgagccatt
    13441 ctgttcaaga tgcttgttta ggggaaggtg aaggctgttt atctgttgat cgagaagtac
    13501 caggatatgt tgttcgccat gccaaaatca ctgtgtctta ttatgatatg aatggtgaaa
    13561 aacacaagat tcgtttgaag aattatgaat cgatcgtcgt tcaacatgaa atcgaccata
    13621 tcaacggtgt gatgttctat gaccacatca acgatcaaaa tccatttgca ctaaaagaag
    13681 gcgtattggt gatcgagtag agaattggca ggttccttcg atactatgct acaagaaagc
    13741 tttataaaaa aggggagtgc tcaaaagctg cacttccctt ttttatgttt ctccactaat
    13801 cgaaatttag atagacatct agaaatcgca attccaaaaa attctgtgta ttggatacgc
    13861 atcttttctt attttttctt atttcttcca tatgggtgtt tatctcagag atgatagaat
    13921 agtttctagg ataaaaagta gcagctacga tgttatcctt cgtagaggat tcctgcttca
    13981 gctagttttt gtttgatgtt tttcagcata tgcttttctg ggtagcggat cgtatgcaga
    14041 tggatgccgc ctgttaattc ggataacaaa gtagcattac ttttttgata acgtctcata
    14101 aaggaatcga tatcttgtgg cgttttgatg tgcaaagttc ctgctaactc accgtaaagg
    14161 ggatgttcca caattacatc aatgatttca ccaccatttt caacgattag tctcagttct
    14221 tcttctgttt gatcttttcc atgctggaca gcgattttac tgatgtgccc agtattggtt
    14281 tcttctgttt cgaggatata acctcttgct gttgccacga tacttttacc tgcagctcgt
    14341 agtaaagcaa tatcgcctac aatgatctga cggctgactc caaaagtttt cgcaaacttg
    14401 ctagcactca ctggtttttc tgtatttgcc aaggtttgca tgatttgttt tcgccgtgtc
    14461 tctccttcga tcacacttat tcctccttca ttttgttttg gtattcgcgc gagtgtttca
    14521 tcaaatcaac atacgtgtct gttattgttt ccttatatcc cttatttttc agcagactaa
    14581 caactttatc caatacttgc tgctctcttt ttgcatcata aactgcttgg ttttcttctt
    14641 ttttcacttg tcctatttta gttaccgtat ccattctttt ttctaataaa gcaaccaact
    14701 ctcgatcgat catatcgatc ttatgacgta atgtttcaag agactcttct gttagttctt
    14761 cctctactgt cttgatgata cgagcaggat ttcctgcaat cactacattg tcgggaaaag
    14821 atttggtcac aaccgaacct gcgccgacta ctacgttgtc ccctagagtg acacccggcg
    14881 tgacgataac tcctccgcct aaccaaacat tattaccgat tttaatgggt tttgcgtact
    14941 ccagaccgct gttacgtttc actggatgta gtggatgcgt cgccgtgtaa agctggacat
    15001 tcggagcgaa catgcagtta tcaccgattt caatcgtgct gacatctaaa aatgtacaat
    15061 tgaaatttgc ataaaaattc tccccaacaa atatattata tccgtaatca aaattgataa
    15121 ctggctccat atagattttt ttccctgtac ggccaaaagt ctctttcaac aattgggatc
    15181 gcagttccgc tgattctgct tggttgatga tttggctttg acttcttgca aacatacggt
    15241 cggcaaccag ctcaggatca ttggcaaaat aaagctcgcc tgcaatcatt ttttcttttt
    15301 cggttttgaa ttcagtcata atctgctcct aattcttgta tttttttgaa aacaaccgct
    15361 ccgtcttctt gaataaacgt ataaggctcc gctaaataaa caggcgtttg attgattact
    15421 aagattttgg ctgacggctg gcgaaactgt accagatcac aaaacggatg aacttgaaaa
    15481 ctcgttccaa caatgacgat cagctctgct tggctgacgg cataagccgc ctgctccatg
    15541 actccatctt gaaacccttc accatataac acgatgtctg ggcgtatttg tcctccgcat
    15601 gcttgatgtt tgtcgctgtg aagatattct ttccagtcta ccgtttgttg acattttcga
    15661 caatgacatt gatacagact cccatgaaaa ttgacgagtt gcgggctttt agcctttgcg
    15721 tgcaaaccgt cgatgttttg ggaaacaacc caaacatttt tttctttcgc tagatgtgct
    15781 atttccaaat gaatgatatt gggttttgct tcaggatgat aaatcttttt gacaaattga
    15841 tagaatttat ccggttcatt caccattgct tgatgactca gcaagtattc cggctgctcc
    15901 atcccgtggt agattcctga caaagatcga tagtctggca ctccagaagg tgtggatacc
    15961 cctgcaccgg tcaaaaatgt aatttgctga taagctaata tctcttttgc tgcttcgtct
    16021 actgttaatt gtttcatgtt ttgtcacctc actttccatt atagcccata ctcgaacaaa
    16081 tttattgttg aaaagtcaga aaaatgggaa taaaaaagtg ttatgggcat ttgagcaatt
    16141 tatcacaatg ttcactgaca aaagaatgaa aacgtgttac aatactgctg tataaaagtg
    16201 aggtgaatcg atatgttacc attctttatt tattggggcg ttattctggc ttgtatcgcc
    16261 tggttagcgt taagcgttta tttctctgtt ttttatcttg tacgcaaaga aaatggaaat
    16321 ctttgggctt ttgctttatt caacgtgatt gccgcaattg ttttagccat tacattagcc
    16381 gtatatcgaa catggggctg gggaatcacc caatactcaa gtttgattta tctaatatta
    16441 gccatttatg gcgtcgttgt tcttttgcaa gcgatcctag gacgtgagcc aaagaaagcg
    16501 gcagcttaaa tgatcgagat ggaactggac acaggaaatt ttctgttcta gttctttttt
    16561 tattgtatta catacatttt tgtgtataat tatactatcg tttgcaatgg atagatgatt
    16621 cacattttga ttgttttttc ggtaaaagta aagatttcta tatttatcag tattttttca
    16681 aaaaccagca gttatagatt gacaaagcct ctcgagtatc gtaaactttt tttgtataaa
    16741 taactgaata cgagatgcct caatcaatga ggtagaggtc gcgagaatca ttaaccctgt
    16801 ggagtgaagc aaacatggag aagcaggaat agggaggatc gccgaaatgt gcactttttt
    16861 gcttggagtg tatgttggga cgcaagttaa gagcttgcgg actgtcttag cagtgatgct
    16921 aagttgcgct atgttttgtg agaggtttat caccttatgg aattttagcg gcctttttat
    16981 atctataaat cggtcgcttt ttattttttc agataaagct ttaccgcatt tcatctagac
    17041 cgctcgtgta tcatataatc agaaagggag aaaaaaatga aaaaaaatat ggtttcagtt
    17101 gccgtactat ttgcttttgt cttctcacta ttcagtgtgg gatctctggc aaatgcagat
    17161 gaaaaaacac cgagcgatga gtttcgcgta ggtatggagg ctgggtatgc acccttcaac
    17221 tggtctcaac aaacagatga gaataatgcc ttgccaattc aaggccaaaa tagttacgcc
    17281 ggcggttatg atgttcaaat cgctaaaaaa gtagcagatg gtttagggaa aaaattagtc
    17341 atcgtccaaa cgaaatggga tggtctggct cctgcccttc aatcaggcaa gatcgacgcg
    17401 atcatcgccg gaatgagccc tactgctgaa cgacgaaaag aaattgattt taccgatcct
    17461 tattacgaat cacaattagt agtagtagtt caaaaagata gcaaatatgc aaaagcaaaa
    17521 agtttagcag atctttctgg agcaaagatc actgctcagt taaatacatt ccactatact
    17581 gtgatcgatc agataccaga tgtgcagaaa caacaagcaa tggataattt ctcagcaatg
    17641 agaacagctt tagcttctgg aatgatcgat ggttatgtca gcgaacgtcc ggaaggtgta
    17701 acggcaacta gtgtgaacaa agacttggaa atgcttgaat tcagcggtgc agatggcttc
    17761 cagacaaacc cggaagatgt tcagatttct gttggtatgc gtaaaggcga cccggatatc
    17821 caaaaagtaa accagattct ttctggcatc tctaacgatg aacgaaccaa aattatggac
    17881 caagcagtca aagatcagcc tgctgcaact gatagtgaag aaaaacctgg catcatttct
    17941 gatttcacta cgatttggaa acaatacggc aatatgttct tacgaggtgc tggacttacc
    18001 ttgttcatcg cattgatcgg gacagttgtc ggtactacac ttggattact gattggtgtc
    18061 ttccgttcgg tacctgaatc aggaaatgca ctgactcgct tcttccaaaa aatcggaaat
    18121 gcacttcttt ctatctatgt cgaagtattc cgcggaacac cgatgatggt acaagcaatg
    18181 gtcatcttct acggtctggc actcgctttt ggcatttcat tgaaccgaac gattgccgct
    18241 ttgtttattg tctctctcaa tactggagct tacatgacag agatcgttcg tggggggatt
    18301 tttgcagtag atgaagggca gttcgaagct gcgcaagcca ttggtatgac ccatggccaa
    18361 acgatgagaa aagttgttat tccacaagtt ttacggaata tcttgccagc aacaggaaat
    18421 gagtttgtta tcaatatcaa agatacagca gttttaagtg taatcggcgt agctgatttg
    18481 ttcttccaag gaaactctgc ttccggtgcg aatttccaat tcttccaaac atttacgatc
    18541 gtcgggatca tctacttagt catgaccttt acgatcacca gaatcctgcg ggcggtagaa
    18601 aagaaaatcg atggtccttc agcttatacc aagcttgaag aaatcgacaa ttcaaatttg
    18661 caggaataag gaggaagaat catgaatgaa aaaattattg aaatcaaaca tctaagaaaa
    18721 agcttcggtg aaaatgaagt attgaaagat atcagcgtaa cagtcaataa aggtgaagtt
    18781 gtgacgatca tcggttcttc cggttctggt aaatctactt tcttgcgctg tatcaattta
    18841 ctggaaaaac caacaggcgg cgagatcatt tataatggag aaaatgtatt agctcctaaa
    18901 tataatttac ctaaatatcg aacgaatcta ggtatggttt tccaatcctt caacctgttc
    18961 aacaatatga atgtcttgga aaactgtatg tctggtcaaa caactgtcct gaaacgagat
    19021 aaagaaactg ccaaaaaagt agcaatcgaa aatctggaaa aagttggtat ggatcgttat
    19081 atcgaagcca aaccagcaca attatctggt ggacagaaac agcgtgtcgc aattgctcgg
    19141 gcattatcaa tgaatccaga tgtattgcta ttcgacgaac ctacttcggc gttagaccct
    19201 gaaatggttg gcgaagtgct taatacgatc aaagacttag cacatactgg cttgacaatg
    19261 cttatcgtga cgcatgagat ggaatttgca aaagatgtat ctgaccgtgt catttttatg
    19321 gataaaggtg tgattgcaga agaaggtaca ccagaagata tctttgtcca tccgaaagaa
    19381 gaacgtacaa aagaattcct ttcacgtatt ttaaatgctt aggatcaata gctgattggg
    19441 acaaagagct gcggtgttta ccgcagttct tttttatgaa ttactcataa aaggtaaatt
    19501 tctgaa
//
LOCUS       DAZKKZ010000057        18345 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.058, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000057 DAZKKZ010000000
VERSION     DAZKKZ010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18345)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18345)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18345
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.058"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            430..816
                     /locus_tag="ACG8LA_002137"
     CDS             430..816
                     /locus_tag="ACG8LA_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HFQ0204421.1"
                     /translation="MSDNDERVNAQLIRFFEKVILNTANTYYKKQEEIQKHEQLDQLP
                     PYLFTKDTIKFKQPINVLNVTLLVEDIKLAKILPLLKEPEQIFLIEKFIFNKTDKEIG
                     KVLGITRQGATNLKHRLYKKIQKMLV"
     gene            914..1105
                     /locus_tag="ACG8LA_002138"
     CDS             914..1105
                     /locus_tag="ACG8LA_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0204422.1"
                     /translation="MNTLKEDFILAKNGNEEAVVAILKRFSALVHKQSWRTGKYDQDC
                     YQECMLAIYLAISKFEIKE"
     gene            1619..1951
                     /locus_tag="ACG8LA_002139"
     CDS             1619..1951
                     /locus_tag="ACG8LA_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFQ0204423.1"
                     /translation="MKKTYDRKFKLKISQDILEKKVTTKKIAEEYNISRPTISRWVSE
                     YRRYGKNAFAGQGKRLPDKADFYILEQENKRLKEEDECSTNTKIDTDLQGSLKNFTMK
                     ESKSINVL"
     gene            1861..2064
                     /locus_tag="ACG8LA_002140"
     CDS             1861..2064
                     /locus_tag="ACG8LA_002140"
                     /inference="COORDINATES: protein motif:HMM:NF024673.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HFQ0204424.1"
                     /translation="MFYEHKDRYGSPGITQKLYDEGIEINKRVVAVLMREMNLCTRGF
                     HRRKSSHGREKTIKEMVKKMLNR"
     gene            2095..2241
                     /locus_tag="ACG8LA_002141"
     CDS             2095..2241
                     /locus_tag="ACG8LA_002141"
                     /inference="COORDINATES: protein motif:HMM:NF012870.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204425.1"
                     /translation="MTDITYIPCNDGRLYLSTYIDLATRILRYYMVDSHMKKEIVVRP
                     LQIY"
     gene            2248..2403
                     /locus_tag="ACG8LA_002142"
     CDS             2248..2403
                     /locus_tag="ACG8LA_002142"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="DDE-type integrase/transposase/recombinase"
                     /protein_id="HFQ0204426.1"
                     /translation="MPTVIHSDRGSQHRSFIYQELLTDHHITHSMSQTGTPVDNAVIE
                     AFHRSIK"
     gene            2679..4019
                     /locus_tag="ACG8LA_002143"
     CDS             2679..4019
                     /locus_tag="ACG8LA_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HFQ0204427.1"
                     /translation="MSYSEFTKELLDILDLNLTFHEDAFRKERINDETCFVFDGTLTY
                     QPEECFHCHYQNKQTIIKWGWKKVSILLNDVSNYKTIVRINKQRFKCKHCGKTFLAED
                     SVSDRRCSIARRVKQAILELLSEPISMSLIARMKHISPTTVIRILRSLRPKTVSLNQP
                     LPEVVCFDEFKSVKNVSGAMSFVMMDGKTHQLIDIVENRQLNPLRDYFLRYPRKVREQ
                     VRLVVSDFYTPYRTLVKECFPNARIVADRFHISQHIGRAFTNHRIQVMKTFKKGDRRS
                     KHLKKYWRLLQKNAWELNGQHRYWRPSFRDHLTEAEIVDRLLYYDDSLKRGYEVYQVF
                     LSAIRRQDVPEFVALLKEDYKELPEHYQPVFTTFKKYRTEIKRALRVPYSNGPIECLN
                     NHIKVLKRIAYGFRNFQNYRERIFLYRGKYFKKTKNTTQLTKARTTTRLDKIAV"
     gene            complement(4260..4667)
                     /locus_tag="ACG8LA_002144"
     CDS             complement(4260..4667)
                     /locus_tag="ACG8LA_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HFQ0204428.1"
                     /translation="MKFLRKAGVKIGDVIIIGILIIPSFIPLFVFSIEKENETTEDAI
                     KYAIVQIDGKEMDRFDLDKINHKLVNYHPAKGQYNIVEIKDGRIRVKEDNSPDQIAVR
                     TGWISKPGQTSICLPHKLVISIEKKESKDYYIY"
     gene            complement(4856..5866)
                     /locus_tag="ACG8LA_002145"
     CDS             complement(4856..5866)
                     /locus_tag="ACG8LA_002145"
                     /inference="COORDINATES: protein motif:HMM:NF014542.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HFQ0204429.1"
                     /translation="MPITILTGYLGSGKTILLNHILYGDHGKEIAVIVNDIGEVNVDG
                     VLVDKKGFKRTGEKLVSMPNGCICCTLREDLIVELDQLVQFSDLNQIVIEASGISKPI
                     PIIQAIILAKNPLDIDLTQRLEIGAIIIVVDVKRFWDNFETGEKIQERKAEGNVVEEE
                     QDIRGLLIDQFECCNILLLNNSDLVSTKTIYKINGLIAKLQSNAKIIRTIKGEVDLSK
                     ILNTNLFNIDETSYSMGWFKELELGYQNHIPETEEYGISSFIYRNRLLLDAQKFAHLT
                     DKNFPGNITRAKGFLWFAQHSDFSTIFETSGSHKSIESLNYWVASLPKIECQMIIQKN
                     PN"
     gene            5992..6210
                     /locus_tag="ACG8LA_002146"
     CDS             5992..6210
                     /locus_tag="ACG8LA_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0204430.1"
                     /translation="MSQYCHLTILKRERIFLLHEEGFSISIIGNDIQHSPFTILHELR
                     RNKKKTNHLPKRKKIMLIEEKNADVITF"
     gene            6303..6866
                     /locus_tag="ACG8LA_002147"
     CDS             6303..6866
                     /locus_tag="ACG8LA_002147"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HFQ0204431.1"
                     /translation="MDFSISFITIYRAICNDLFDTEPLSHGNKGLIRSLHHRGKTRHT
                     KNHVESRGKICLTHSIHGHPKSADDRSDFGHWKADIVAGKTSGTCLVTLTDRKSCFLL
                     AGKKVPRKKAAYVSEKMIELLSSIPNEAVKTITPDRGKEFSNHFAVTEVLNNMPFYFP
                     DPHALGNNEQIKIRIDSFENTCQNRKR"
     gene            complement(7059..7298)
                     /locus_tag="ACG8LA_002148"
     CDS             complement(7059..7298)
                     /locus_tag="ACG8LA_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0204432.1"
                     /translation="MVRKVLLSMDSKNIDAYRRYQFAKQMRLNGSTLADIAATLHVSI
                     DTVHRVLKRDPDCCFIKVNTGRSRRLAKRHNSLAN"
     gene            complement(7322..8845)
                     /locus_tag="ACG8LA_002149"
     CDS             complement(7322..8845)
                     /locus_tag="ACG8LA_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HFQ0204433.1"
                     /translation="MKKISVGLIGIAALGLLGACSSTNDAKVSNDKDGKLEIVTTFYP
                     MYDFTKNIVGDEANVDLMVPAGSEPHDYEPSAKDMAKAHDADVFVYHNENMESWVPKA
                     KESWKKAGPNVVEGTKDMILLPGSEEEDHDHGEEDHHHELDPHTWVSPKMAIKEVSNI
                     KDQLVKLYPKKAKVFETNAEKYLTKLKRLDADYTTSLKEAKQKSFVTQHAAFGYLALD
                     YGLIQVPIAGLSPEEEPSSGRLAELKEYVKKNKINYIYFEKNANDKIAKTLANEAGIK
                     LEVLNPLESLTKEQMDNGEDYVSVMEDNLKALEKTTMVAGEEVVPEKEAKDEKTVANG
                     YFKDADVKDRELSDYTGEWQSVYPLLKDGILDEVFDYKAKLNKDMTAAEYKDYYTTGY
                     KTDIDTINIKDNTIDFVVNGEHHQYTYKYVGYKILNYEKGNRGVRFNFETDDAGAGRF
                     KYIQFSDHGIAPSKAEHFHIFFGGESQEKLYNEMHNWPTFYPASLSEHEIAQEMMAH"
     gene            complement(8863..8985)
                     /locus_tag="ACG8LA_002150"
     CDS             complement(8863..8985)
                     /locus_tag="ACG8LA_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HFQ0204434.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKEHKQNKMKKLA"
     gene            complement(9015..9998)
                     /locus_tag="ACG8LA_002151"
     CDS             complement(9015..9998)
                     /locus_tag="ACG8LA_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HFQ0204435.1"
                     /translation="MGIPVTIVSGFLGAGKTTLINQALQVSPYPREEIIIIENEFGEV
                     GIDHKLLVHSEERVLQLNNGCMCCSLRSDLLAILISLLETIEEHQQPISQIIIETTGI
                     ADPQPIIQTLLTAPQLRGRVYIDSLLTVIDSDSFELIEREPQALKQLVIADRIFVSRK
                     QNLNLSALKKLQREIKSINPLSDIRMFTHSETIQKKDFYNLEKFNHPLVFESDSSENH
                     YNGKHYHQHHQEHEFKSILLTSDQDIKKDFLFQLIDRLILTNQGSLYRFKGLIALQDQ
                     DFIVAIQGVNEQVNFQYTTRQKDQTTIILIGKMLDEERIKQSFDKLLAESK"
     gene            complement(10022..10171)
                     /gene="rpmG"
                     /locus_tag="ACG8LA_002152"
     CDS             complement(10022..10171)
                     /gene="rpmG"
                     /locus_tag="ACG8LA_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HFQ0204436.1"
                     /translation="MRQNIILECVETGERLYLTSKNKRNNPERLELKKYSPKLRRRAI
                     FKEVK"
     gene            complement(10192..10569)
                     /locus_tag="ACG8LA_002153"
     CDS             complement(10192..10569)
                     /locus_tag="ACG8LA_002153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204437.1"
                     /translation="MEIIYPPLVEEGLKYYLETTQQSLDKCTFYRSMVERGIITETGL
                     PTQQAIENGLVKDYYEDQGLSFDDFLRIYPIFEEYDEELFQCIDGYWEIPVDMKENLV
                     SQLESGELTFEDAQQIQAYLEDR"
     gene            complement(10601..10780)
                     /gene="rpmF"
                     /locus_tag="ACG8LA_002154"
     CDS             complement(10601..10780)
                     /gene="rpmF"
                     /locus_tag="ACG8LA_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018345355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HFQ0204438.1"
                     /translation="MAVPARKTSKAKKRLRRTHQTVVKPEISFDEANGDYRRSHHVSL
                     KGYYNGKKVIKGASK"
     gene            complement(10795..11064)
                     /gene="rpsN"
                     /locus_tag="ACG8LA_002155"
     CDS             complement(10795..11064)
                     /gene="rpsN"
                     /locus_tag="ACG8LA_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HFQ0204439.1"
                     /translation="MAKKSKIAKAKKQMAMIEKYADKRQELKAAGDRTALAKLPRDSN
                     PNRLRLRDQTDGRPRGYMRKFGMSRIKFRELAHQGLIPGVKKASW"
     gene            complement(11587..13353)
                     /locus_tag="ACG8LA_002156"
     CDS             complement(11587..13353)
                     /locus_tag="ACG8LA_002156"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0204440.1"
                     /translation="MQMIGGLTMKSFYKNKFALTNQGAEDLVKASISSFFVYCINMVP
                     AFIIMMLIDELVLENVKPPWLYFTVSFVTLLFMYWLLDREYENLYNSTYKESAHLRMQ
                     IADDLSNLPLSYFSKHNLSDLSQTIMSDVEGIEHAMSHAIPKAGGMALFFPFISVMLL
                     VGNVKMGLAVILPTLFSFVLILLSKKSQTKANTKYYDTLRENSEEFQETIELQQEINS
                     FNLSKKVQDRLFKKMEESERIHLKVELSTFSVMALSSIFSYVSLAVVILVGVHLLLTG
                     EVTILYVVGYLLAAIKIKDSFDSMKEAVLEIFYLAPKIQRIRAMKETSIQEGSDSPLK
                     SFDIELRDVSFSYDNNTPILDHISFTAKQGEVTALVGASGSGKTSILKLVSRLYDYDE
                     GCILIDGYDIKRVSPASLFSKIAIVFQEVTLFNTSILENIRIGNSQASDEEVKKAARL
                     ANCEDFIEKLPDGYHTLVGENGSSLSGGERQRLSIARAFLKNAPILILDEITASLDAE
                     NEKRIQESLNRLIQDKTVLIISHRLKSIEKVNKIVVMDQGKIVDQGTHSELYRRSEIY
                     KNLIKKTKLSEKFVYEKEAQSR"
     gene            complement(13313..15067)
                     /locus_tag="ACG8LA_002157"
     CDS             complement(13313..15067)
                     /locus_tag="ACG8LA_002157"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0204441.1"
                     /translation="MKVYKKLFSYVPKMKYYGWLATLFSDFSVVLTVYGYYSIYKFLK
                     SLIIVGDEYLAKSYAVQTVAWLTLGALFYIFSGLFSHILGFRLETNLRKKGISGLTEA
                     SFRFFDLNSSGYIRKTIDDNAAKTHMAIAHLIPDSAQAIVTPVLSVALGFFINFKIGL
                     VLIAMLVIGVFLLKKMTENTNFIQKYQESLDVLSSETVEYIRGIQVIKIFGAKVTSFK
                     ALNKAINDYAKFAYKYSLSGKTPFVLFQWLFFGIVCILIVPITFFITSLTTPKILAVD
                     LLMLFFLSGIIFVSFMRIMYVSMHLFEARYAVETLDSLYLEMKQDQLKYGNETQIKNC
                     DIAFENVSFSYKEECVLENFNLVLEQKRIYALVGKSGSGKSTIAKLISGFYNVDKGQI
                     KIGGKPLNHYSKDTIINTIAFVFQDTKLFNQSIYDNVSIANPQAPASKVFDALRLAGC
                     ESILEKFPEREHTLIGSKGVYLSGGEKQRIAIARAILKDAKIVIMDEASASIDPDNEY
                     ELQKAFQHLMKEKTVIMIAHRLSSIKSVDEILVLSEGKIVERGNHNELMAKHQVYKQL
                     VTNYENANDWRLDNEKFL"
     gene            complement(15177..15746)
                     /locus_tag="ACG8LA_002158"
     CDS             complement(15177..15746)
                     /locus_tag="ACG8LA_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HFQ0204442.1"
                     /translation="MKTKDYIFIGLATVISLVIYFFSIMVSSIGGAFGHSISPGIFGL
                     LSGIIFVYISYNYPRKGIFTIYTIVLLLFFTLMGGAYLPWFISSISMAILADIILSVF
                     GYDRAIPQVASWALMQLGSAAGQWIPIWFFTDRFRQDWIDKGQSAATMDAMIHYAVGI
                     WGIISVLVVASLSMIGVLIGRKVLKKYKK"
     gene            complement(15764..17179)
                     /locus_tag="ACG8LA_002159"
     CDS             complement(15764..17179)
                     /locus_tag="ACG8LA_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0204443.1"
                     /translation="MFEFNNVSFSYKDVKEQALVDLNFSIKKGSLTLITGSSGSGKST
                     LLKLMNGLIPRLYDGKLVGEILFENNSLQSLTQESISKNIGYVSQDPRGQFFTTNTTS
                     ELVFSMENFGFTKEHMDKRINELAELLDLSNILDKNIFSLSSGERQKISIGCSLSLNS
                     KLIILDEPSSNLDFKATKKLADLLCDLKNKGFTIVIAEHRFYYLKELIDQVLFVKNRT
                     VKTTTIQLLKTENNNALRKFDIFNSSIEVPYIEKVSADVLKVEEITYENILKDINFDV
                     KVGDVIGLVGKNGVGKTTLLRILMKIIRPTKGKIIENKKNLSSPFLVMQEMDYQFFTE
                     SVRSELALGNEIVSKDQQEKILKKMELYKMKDQLPFDLSGGEKQRLLVSIASLSKTNL
                     FLFDEPTSGLDYINMERIADLIKDLKEKGAVVIATHDPEFLYKTCNRIIYLKNGGIKK
                     DIKLRVEDSTLIEQIFNDITK"
     gene            complement(17190..17858)
                     /locus_tag="ACG8LA_002160"
     CDS             complement(17190..17858)
                     /locus_tag="ACG8LA_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     component T"
                     /protein_id="HFQ0204444.1"
                     /translation="MSKINPLTLITLNIFFPVIIFLGKGNIFQVGCFIIATVLVLMFR
                     KIKTCIYFILIYSVLFLVMKIIDAIKIEFFTIFFGTSLYIVFRMLPVVMISWLLVSVY
                     TSNELLSSLEKIHLPKKIMLSITVVIRFFPTYRSEIRMIKESLKMRNIRLSFFQPLQY
                     LEFLLVPVLIRATMIAEEMTANAITKGIESPVKRSSYYKTNMSLLDYIILFSVTIFFL
                     SILI"
     gene            complement(17989..>18345)
                     /locus_tag="ACG8LA_002161"
     CDS             complement(17989..>18345)
                     /locus_tag="ACG8LA_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFQ0204445.1"
                     /translation="SWRENFNELDPFINYIFENKRIFDLVLFQSAGTKYQDIVEKITS
                     FVTKKTVCCLDKLKTIGMINQNLVFNEEEIHFYIYSFYATFYDILKHSYSKEKTMLLT
                     RRLYQFSVPGWIELLS"
BASE COUNT         5994 a         3447 c         2723 g         6181 t
ORIGIN      
        1 tttttcgttt ctaaatactc caatttggga atccaataaa aattttcgtt caaatacgtg
       61 tctattcgaa ctcttttcta gttgttaatt atgaaggggg aagaaataaa aaatacaatc
      121 tatacacgaa taagaatatt atccaaaagg aggttttaga aaagatttat tatacgtaaa
      181 aagctcaaga cattttctta gccataagga catgtttgat atttaagaag atatatgaat
      241 tttcttttct aagtataaag ataactatcc attatcaact aaaaaaacat ttttgaaaat
      301 aaacatcagc agtcctatca atgcatgtga gcttatagaa gttattcgca gcgcagcata
      361 attgcattag cttcttttcg tgttttttgc ctcttttccc tttaaatctt aatggaggag
      421 gtgtgcaata tgtcagataa cgacgaacgc gtaaatgccc agttgattcg attctttgaa
      481 aaggtcattt tgaacaccgc taatacttat tataaaaaac aagaagaaat tcaaaaacat
      541 gaacaacttg atcaactccc accatatttg tttactaaag atactataaa atttaaacaa
      601 ccgattaatg ttttaaatgt gactctcctt gttgaagata taaaattagc aaaaatcctt
      661 cctttgttga aagaacctga acaaattttt cttatcgaaa aatttatctt taataaaact
      721 gataaagaaa ttggaaaggt tctgggtatt acaagacagg gtgcgacaaa tttaaaacat
      781 cgactttaca aaaaaattca aaaaatgctg gtttaatatc tgcataataa ctaattttgt
      841 atgcttcttt gctcgtcctc ctccttcccc aaaaaataaa tagattataa gttcatggga
      901 agaaggtaaa tttatgaata ctttaaaaga agatttcatt ttagcaaaga atggaaatga
      961 agaagcagtt gtggccattc tcaaaagatt tagcgctttg gtccataagc aatcctggag
     1021 aactggaaaa tatgatcaag attgttatca agaatgtatg cttgcaatat atctagctat
     1081 ctcgaaattc gaaattaaag aataactcaa ctaagggagt ctgtgacata agtaaaaaga
     1141 tagtttcaaa tttcgaacaa taaatttgaa gccatcttct ttataattat aaagtatcga
     1201 ttttacagcg ttctataatg attcatagaa tctaaaacga atgattttaa ttattaacgt
     1261 tttttaattc gtttttagct taaaaataac ttttgtcaca gtctcactcc taaaattact
     1321 ttatttacgt acgaagtggg caggaggtcg aatccagaac tgggccatgg tacttcaacg
     1381 aggacttctc ctctagaatt gaaaagcatg cgatttacct tccgtaacga cggtagattt
     1441 attcaactat gtgtccaatc aaaatttgtc tgatttcaaa aatagtcaag agaattttgg
     1501 ttgttaaaaa ctcttatcta tcaacttcca cagtttagtt gacaaaccct gatactaagt
     1561 tgggctatga tacacttttc ttgactatca gttacgttac cggaaggaat gaactctatt
     1621 gaaaaaaaca tatgatcgta aatttaaact aaagatttca caggatatcc ttgagaaaaa
     1681 agtaactacc aagaaaattg ctgaagaata caatatctct cgtccaacaa tttcccgatg
     1741 ggtttcagaa tatcgtcgat acgggaaaaa tgcttttgct ggacaaggaa aaagattacc
     1801 tgataaagca gatttctaca ttcttgaaca ggaaaataaa cgactaaaag aggaagacga
     1861 gtgttctacg aacacaaaga tcgatacgga tctccaggga tcactcaaaa actttacgat
     1921 gaaggaatcg aaatcaataa acgtgttgta gctgttctta tgcgtgaaat gaatttatgc
     1981 acaagaggat ttcatcgacg caaatcttct catggtagag aaaaaacaat caaagaaatg
     2041 gtaaaaaaaa tgttgaatcg ataatttgaa cagaaccaaa ttgatgctgt ttgggtgacg
     2101 gatattactt acattccatg taatgacggt cgcctctatt tgtccaccta tattgactta
     2161 gcaactcgta ttctacgtta ctatatggtg gattcacaca tgaaaaaaga gattgtcgtc
     2221 cgtccattac aaatttatta aggagaattg cctacggtaa ttcattccga tagaggtagc
     2281 cagcatcggt cttttattta tcaagagctg ttgaccgacc accacatcac acattcaatg
     2341 agccaaactg ggactcctgt tgacaatgca gtaattgaag cgtttcatcg atcaatcaaa
     2401 tgagaattaa tcgactccaa caaatataaa agtaaaatag agatgaaggt gttaatccaa
     2461 gattatttag aagactacta cccaaacaaa agaatccata caaaatttat gatgactcct
     2521 tgacaatttg aagcgaagaa aataagggat ctataatatc tagtgttggt gacgccttct
     2581 gttgccaata ctttttcttt tttctaataa acgcaaacag acaccttgaa atcctttaga
     2641 ataaagtcga cgaaaaccat tcaaaggagt gtttcaagat gtcctattca gagtttacca
     2701 aagagttact agatattcta gacctaaatc ttacctttca tgaagatgcc tttcgcaaag
     2761 agcgcattaa tgacgaaaca tgttttgttt ttgatggcac attgacctat caaccagagg
     2821 aatgcttcca ttgccactat caaaataagc aaacgatcat taaatggggc tggaaaaaag
     2881 tatccatctt attgaatgat gtcagtaact acaagaccat tgtgcggatt aacaaacagc
     2941 gcttcaaatg taaacactgt ggaaagactt ttttagcaga agattcagtt agcgatcgtc
     3001 gctgctccat tgcccgcaga gtcaaacaag ccattcttga gctattaagt gagcctattt
     3061 ctatgtcttt gattgcacgt atgaagcaca tttctccgac cactgtcatt cgaatacttc
     3121 gcagccttcg gcctaaaacc gtttctttga accagccgtt accagaagtg gtgtgtttcg
     3181 atgaattcaa atcggtgaaa aacgtctcgg gagccatgag ctttgtcatg atggacggca
     3241 agacccatca actgattgat attgtggaaa atcggcaact caatccttta cgcgactatt
     3301 tcttgcgcta ccctagaaaa gtccgtgaac aagtacgtct agtggtttca gatttctata
     3361 caccctatcg cacattggtg aaagagtgtt ttccgaatgc ccgaatcgtc gccgatcgct
     3421 ttcatattag ccaacacatc ggtcgggcct ttaccaacca ccgaattcaa gtaatgaaga
     3481 cctttaaaaa aggggatcgt cggtcgaagc acttaaagaa atactggaga ctacttcaaa
     3541 agaatgcgtg ggaattgaat ggtcagcatc gctactggcg tccgtcattt cgagatcatc
     3601 tgacagaagc ggagatagtc gatcggctat tatattatga tgactcctta aagcgaggct
     3661 acgaagtcta ccaggttttt ctttccgcta tcagaagaca agatgttcct gaattcgtcg
     3721 cgctcctaaa agaagactac aaggagttgc cagagcacta tcaaccagtg ttcacgacct
     3781 tcaagaaata tcgaacagaa atcaaacgag cgttgcgagt tccctattcc aacggcccta
     3841 tagaatgttt gaacaaccat atcaaagtac taaaacgaat tgcctatggc tttagaaact
     3901 ttcaaaacta ccgagaacga atctttttat atcgaggaaa atatttcaag aaaactaaga
     3961 acactaccca actgactaaa gccagaacaa caacacggct agacaagata gctgtctagc
     4021 cgtgtgagta tctcgattat tctattgaat ttcttcacca acactcattg acgaagagcc
     4081 aaaataagta atctaaccga ctgttaacta aaccattgca ggtcccgtta aagatacttg
     4141 tgcctgttgt caccgcttct ttttcttgtc cacaagcgct taacacactt aataaagccc
     4201 ctgctattat taataataat atctttttct tattaaaaac ctcctcatct atttccagat
     4261 tagtaaatgt agtaatcttt gctttctttt ttctcaatac taataactaa cttatggggt
     4321 aaacaaatac tcgtttgacc gggttttgag atccatccag ttctaaccgc gatttgatca
     4381 ggactattat cttctttaac tcgaattctt ccatctttaa tctcaacaat attatattgt
     4441 cccttcgcag gatgataatt cacgagttta tgattgatct tatccaaatc gaagcgatcc
     4501 atttccttgc catcaatttg aacgatggca tatttgatag catcttcagt tgtttcattc
     4561 tccttttcta tagagaatac aaataaggga ataaaagagg gaataatcaa aatgccaata
     4621 attatgacat cgcctatctt gacaccagct tttcttaaaa atttcattaa cgatatctgg
     4681 ctaaacatat tagaattttt ccatggaaat ggtgaaattt ttcggaaatt atctgcatta
     4741 agagaatcag ttaaacaacc ctcaagttgt tccttaatac attgttgatc catcttcata
     4801 ccaataaaaa ctagtttatt aatgcgttca ccaaacaacg gatgccaggc ttccttcaat
     4861 tcgggttttt ttgtataatc atttgacact caattttagg taaactagct acccaataat
     4921 ttaatgattc aatactttta tggctacccg atgtttcaaa gatcgtcgaa aaatcactat
     4981 gttgggcaaa ccaaagaaac ccttttgctc ttgtaatatt gccaggaaaa tttttatccg
     5041 taagatgggc aaatttttgt gcgtcaagga gtaaccgatt tcgatagata aaacttgaga
     5101 taccatattc ttctgtttca ggaatatgat tttgatagcc aagctctaac tctttgaacc
     5161 agcccattga ataggaagtc tcatctatat taaaaagatt tgtatttaga attttcgata
     5221 agtctacttc acctttaatt gtcctaatta ttttggcatt ggactgtaac ttagcaatta
     5281 gaccgttaat tttgtaaatc gtcttggttg acactaagtc actattattt aaaagtaata
     5341 tgttacaaca ctcgaattga tcaattaaca agccacgaat atcctgttct tcttcaacta
     5401 cattaccttc agcttttctt tcctgaatct tttcacccgt ttcgaaatta tcccaaaaac
     5461 gttttacatc cactactata ataatggcac caatctctaa tcgttgggtc aaatcaatgt
     5521 ctaaagggtt tttagctaat ataattgctt gaataattgg aattggtttg ctgattcctg
     5581 aagcttcaat aacaatttga ttcaagtcag aaaattgcac taattgatct agttcaacaa
     5641 tcaaatcttc gcgtaatgta caacaaatgc atccattcgg catcgaaaca agtttttctc
     5701 cagttctttt aaaacctttc ttgtcgacta ataccccatc aacatttact tcccctatgt
     5761 catttacaat gacagcaatt tcctttccgt gatcaccgta cagaatatga tttagaagta
     5821 tcgtttttcc tgaaccaaga tagccagtta agattgtaat aggtattttt tcatagggaa
     5881 cctctttcta taccttgaat ttacacttta agtgcaacac ataaaaatga gtcataatcg
     5941 atatccaact agtataagtt tgtcgagaac actcctagaa ggaaaataat tatgagccag
     6001 tattgtcatc ttactatact caaacgagaa agaatctttc tgcttcacga agaaggattt
     6061 tctattagta taattggcaa cgacattcag catagcccgt ttactatttt acatgaactg
     6121 agaagaaaca agaaaaaaac taatcacctt ccaaagcgga aaaaaattat gcttatcgaa
     6181 gaaaaaaatg cggacgttat cacattctaa atgatccgtg agtttggtca attgttcgtc
     6241 atttatttgt cgattttcag tggtcgccag agaaaatctc gaatcgtttg aagcatgaac
     6301 atatggactt ttcaattagt tttatcacga tctaccgtgc aatttgcaat gatcttttcg
     6361 atacagaacc cctctcacac ggcaataaag gcctgatccg ttcattgcac catcgaggaa
     6421 aaacaagaca tacaaaaaat catgtcgagt ctcgtgggaa gatttgcctt actcattcga
     6481 tccatggcca tccaaaatcc gcagatgata gaagtgattt tggtcattgg aaagccgata
     6541 ttgtagctgg caaaactagt ggtacttgtt tagtgacttt gacagacaga aaatcatgct
     6601 tccttttagc aggaaagaag gtccccagaa agaaagccgc ttatgtgagc gagaaaatga
     6661 ttgaactttt aagcagtatt ccaaatgagg cggtcaaaac gatcactcca gatagaggaa
     6721 aagaattctc caatcatttc gcagttacag aagtattgaa taatatgccc ttttattttc
     6781 cagatcctca tgcccttggc aacaatgaac aaattaaaat acgaatagac tcattcgaga
     6841 atacttgcca aaatcgaaag agatagctac ggtagataac tcaacgataa atcagatgat
     6901 tgaaaaactg aataacagac ctagaaagtg tttagattgg agaacacctt atgaagtctt
     6961 ctttgataaa gtgttgcgct tgatttgaca attcaagaaa taataaaaag cagatcaaat
     7021 ccaaataagg gaaaaatgat ctactctggt attatcaatt aattggccaa gctattatgc
     7081 cgttttgcta aacgtctact tcttccagta ttgaccttga taaaacaaca atcaggatcc
     7141 cgttttaata ctctatgaac tgtgtcaata ctaacatgta aagttgcagc aatatcagct
     7201 aatgtactcc catttaatct catttgcttt gcaaattgat aacgccgata agcatcaata
     7261 ttcttggaat ccatagacaa taatactttt cttaccatgt atttcctcca aagattggat
     7321 tttaatgggc catcatttct tgagcaatct catgctcaga taatgaagct ggatagaaag
     7381 taggccaatt atgcatttca ttataaagtt tttcttgact ttctccacca aagaaaatat
     7441 ggaaatgctc tgccttactt ggtgcaattc catgatcgct aaattgaata tatttaaaac
     7501 gaccagcacc tgcatcatca gtttcaaaat taaaacgaac accacggttt cctttttcat
     7561 aattcaaaat tttgtatcca acatatttgt atgtgtattg atgatgttca ccgttgacta
     7621 caaaatcaat ggtgttgtct ttaatgttga tagtatcaat atctgtctta tagccagtag
     7681 tataataatc tttgtactcg gcagctgtca tgtctttatt gagttttgct ttgtaatcga
     7741 aaacttcatc caaaattcca tcttttaaca acggataaac agattgccat tcgcctgtat
     7801 aatcactcaa ttcgcgatcc ttcacatcgg catctttaaa gtacccatta gcaactgtct
     7861 tttcatcctt cgcttctttt tctggaacta cctcttcacc agcaaccata gttgttttct
     7921 ctaacgcttt tagattgtct tccattactg aaacataatc ttcaccatta tccatttgtt
     7981 cttttgtaag actttcaaga ggattcaata cttccaattt tatcccagct tcattggcca
     8041 aagtttttgc gattttatca ttagcattct tttcaaagta aatataattg atcttatttt
     8101 ttttaacata ctcttttaat tcagctaatc gaccagaaga tggctcttct tcaggactta
     8161 gtccagcaat aggaacttgt atcaatccat aatccaaagc taaatatcca aaggctgcat
     8221 gttgtgtcac aaaacttttt tgtttcgctt ctttaagact agtggtatag tcagcatcca
     8281 accgtttcag tttagtcaaa tacttttcag catttgtctc aaatactttt gcttttttcg
     8341 gatacaattt aactaactga tccttgatat ttgaaacttc cttaattgcc attttgggtg
     8401 aaacccacgt atgaggatct agttcatgat ggtgatcttc ttctccgtga tcatgatctt
     8461 cttcttcact acctggcaat aaaatcatgt cttttgttcc ttctactaca ttaggcccag
     8521 ctttcttcca actttcttta gcttttggta cccatgattc catgttttcg ttatgatata
     8581 caaaaacatc agcatcatga gcttttgcca tatccttagc tgagggctca tagtcatgag
     8641 gttctgatcc cgctggaacc attaaatcca cgttcgcttc atcgccgacg atgtttttgg
     8701 tgaaatcata cattggatag aatgttgtta caatttctaa ttttccatct ttatcattcg
     8761 atacttttgc atcattagtg ctggagcaag ctcccaataa tcctagagct gctatcccaa
     8821 taagtcctac actgattttc ttcattcttt ttccttcctt aattatgcta atttcttcat
     8881 tttattttgt ttatgttctt tgataatttt taatgccctt tttctagttt tgatattcgg
     8941 gcttttaagt cgtcgatatg cactagatat atccgttttc tccattagaa attaccccta
     9001 atcaatactt atcattattt gctttccgcc agtaatttat caaaactctg tttgatcctt
     9061 tcttcatcca acatttttcc aattagaata atagtggttt ggtctttttg tcgagtggtg
     9121 tattgaaaat taacctgttc gtttacccct tgtatggcaa ctataaaatc ttgatcttgc
     9181 aaagcaatca atcctttaaa acgatacagg ctcccttggt tggttaaaat cagccggtca
     9241 attaattgga ataaaaaatc tttttttatg tcttgatctg aagttaagag aattgattta
     9301 aactcatgtt cttgatgatg ttgatgatag tgtttgccat tatagtgatt ttctgatgaa
     9361 tcactttcaa aaactaaggg atgattgaat ttttccaaat tataaaaatc ctttttttga
     9421 atcgtttcac tatgtgtgaa cattcgaata tcggataaag ggttaatact tttgatttct
     9481 ctctgtaatt tttttagtgc agataaattc aagttttgtt ttctagacac aaaaatgcga
     9541 tctgctatga caagttgctt aagggcttgt ggttctcttt caataagttc aaaactgtca
     9601 ctatcaataa cagtcaataa actatcgata tatactcttc ctcttagttg aggcgctgtt
     9661 aaaagtgttt gaatgattgg ttggggatct gctatacctg tagtttcaat gatgatttgt
     9721 gaaattggtt gttgatgttc ttctattgtt tccagtaaag aaatcaatat tgctaataaa
     9781 tcactgcgaa gactgcaaca catacatcca ttatttagtt gtaacacccg ttcctcgcta
     9841 tgaactaata atttgtgatc aatcccaact tcaccaaact cattttcaat tataataatt
     9901 tcttccctgg ggtagggtga gacttgcaag gcttgattga ttagcgttgt ttttccagcc
     9961 cctaaaaacc cagaaacgat tgtaactggt atgcccattt tgtcaccttt ttaccactta
    10021 gctatttcac ttctttgaaa attgcccgtc tgcgcaattt tggcgaatac ttttttaatt
    10081 ctaaccgttc agggttattc cgtttatttt tgctggtgag atacagacgt tctccagttt
    10141 cgacacattc caaaataata ttttgacgca taaatcttcc tccttcaata cttatcgatc
    10201 ttcaagatat gcttgaattt gttgtgcatc ttcaaaagtt aactcgccag attccaattg
    10261 tgaaactaaa ttttctttca tatcaacagg tatctcccaa taaccatcaa tacattgaaa
    10321 taactcctcg tcatactctt caaaaattgg atagattctt aaaaaatcat caaatgataa
    10381 gccttggtcc tcatagtaat ctttgactaa tccattttca attgcctgtt gggtcggtaa
    10441 acccgtttca gtaataattc ctctctctac catcgaacga taaaaagtgc atttatctag
    10501 cgattgctgg gtcgtttcaa gataatactt taatccttct tcaactaaag gtgggtaaat
    10561 aatttccatt ttgattccct cctaaaagtt atatattaaa ctattttgaa gctcctttaa
    10621 ttactttctt tccattatag taccctttta aagatacatg atggctacgt ctataatcac
    10681 cattcgcttc gtcaaatgaa atttctggtt ttactacagt ttgatgagtt cttcttaacc
    10741 gtttcttcgc cttagatgtt tttcttgctg gtactgccat gatatttcct ccttttacca
    10801 acttgctttt tttactccag gaatcaaccc ttgatgggca agttctctaa acttaatacg
    10861 ggacataccg aactttcgca tataccctct tggacgacca tccgtctgat cacgaagcct
    10921 cagacgattc ggatttgaat ctcttggcaa tttagcgaga gcggtgcgat ctcctgcggc
    10981 ttttaattcc tgacgtttat ctgcgtactt ttcaatcatc gccatttgtt tctttgcttt
    11041 agcaattttc gacttttttg ccatatacct ttatactcct tttattttga tttagacatc
    11101 tcaaatcgta atcgttacgt tttgacactg atactttacc aacaagagtt gctcttgtca
    11161 acaataaata acatgaaata aaactcatat gaatagataa ctatttgaaa acgaatttat
    11221 cggtacatag agataatcaa atcatttaaa agaatatgca gtttaagctc tgaaaaataa
    11281 gaattcactt ttattagtcc aatcaaacac aaataccgtt ttaagtagct tttcctctac
    11341 ttaaaacggc aatatgaaag aaactataac tttttattca atcttttatg tttaactggt
    11401 ttatcgccaa ttttttaaaa ctttgattat tccttatatt ataagaatag acattaagtg
    11461 aactaattca atcatactga ttctttcgtg tattcaaaat tagatgctgt ttaataaaat
    11521 tattcttttt gaaaaagaat tataactata tcccaaaaat tgtaggttaa tttaaagcct
    11581 atttcatcat cgtgattgag cttctttttc atagacgaat ttctcagata gtttagtttt
    11641 ctttatgaga tttttgtata tttctgacct tcgatacaac tcactatgag taccttgatc
    11701 aactattttt ccttgatcca tcactacaat tttatttacc ttttcaatag acttcaagcg
    11761 atgcgatata attagtactg tcttatcttg tattaaacga tttaaacttt cctgaatacg
    11821 tttttcattt tccgcatcta aactggcagt aatttcatct aaaattaaaa ttggcgcatt
    11881 tttcaaaaaa gcccgtgcta tggataggcg ttgtcgctct cctccagaaa gtgaacttcc
    11941 gttttctccg accaatgtat gataaccgtc aggtagtttt tcaataaagt cttcgcagtt
    12001 agctaaacga gctgcttttt tcacttcctc atctgacgct tgactatttc caatacgtat
    12061 attttccaaa atacttgtat taaacaaagt tacctcttga aaaacaatag cgattttgct
    12121 aaacaaagaa gctggagata cacgtttaat atcataccca tcaattaaaa tacagccttc
    12181 atcataatca tacagtctag acactaattt caagatacta gttttcccgg aaccactagc
    12241 acctactaac gcagtcactt ctccttgttt agccgtaaaa gagatatgat ctaaaattgg
    12301 ggtattgtta tcatatgaga aagagacatc tcgcaactca atgtcaaaag atttcagagg
    12361 actatctgat ccctcttgga tactggtttc cttcatagct ctaattcgct gtattttagg
    12421 agctaaataa aatatttcaa gcactgcttc tttcatagaa tcgaaggaat cctttatttt
    12481 tattgcggct agtaagtaac caacgacgta gagtatagtc acttcacccg ttaacagtaa
    12541 gtgaacacct actagaatga ctactgctaa actaacatat gagaaaatag aggataaggc
    12601 catgactgaa aaagtactta attctacctt taaatgaatc ctttcactct cttccatttt
    12661 tttgaaaagt ctgtcttgaa cttttttaga tagattaaag ctattaatct cttgctgcaa
    12721 ttctatagtt tcttgaaatt cttccgagtt ttctctcaaa gtatcgtaat atttagtatt
    12781 ggctttcgtt tgggatttct ttgataacaa gattaagaca aaactaaata acgttggcaa
    12841 aataacagct aatcccattt tgacattacc aaccaaaagc atcactgaaa taaaagggaa
    12901 aaacagagcc ataccgccgg ctttaggtat tgcatgactc atcgcatgct caataccttc
    12961 aacgtcagac atgatagttt gagataaatc tgataaatta tgttttgaaa aataggataa
    13021 tggtaaattt gacaaatcgt ctgcaatttg cattcttaaa tgcgcacttt ctttataagt
    13081 actattatat aagttttcat actccctatc taacaaccaa tacatgaaaa gcaaagtaac
    13141 gaacgatact gtaaaataaa gccaaggcgg ctttacattt tctaaaacta attcgtctat
    13201 cagcatcatt ataatgaatg ctggtaccat attaatgcag tatacaaaaa agctagaaat
    13261 agatgcttta accaaatctt ctgcgccctg attagttaaa gcgaatttgt ttttataaaa
    13321 acttttcatt gtcaagcctc caatcatttg cattctcata attagtgacc aattgtttat
    13381 acacttgatg tttagccatt aattcattat gatttccacg ttctactatt ttcccttctg
    13441 acaagacaag aatttcatct acagatttaa tgctggataa tcgatgagct atcataataa
    13501 ctgttttttc tttcatcaga tgttgaaaag ccttttgtag ttcatactca ttatctggat
    13561 caatagatgc actggcttca tccataataa caatctttgc atcttttaaa attgctctgg
    13621 caatagctat acgttgtttt tctcctcctg acagataaac tcctttacta ccaattaagg
    13681 tatgctctct ttcgggaaat ttttctaaaa tcgattcgca accggctaat cttagcgcgt
    13741 caaatacttt acttgctggc gcttgaggat ttgctataga aacgttatcg taaatactct
    13801 gattgaatag tttcgtatct tgaaagacaa aagcaattgt gttaataatt gtgtcttttg
    13861 aatagtgatt taaaggctta ccaccaattt taatctgtcc cttatccaca ttgtagaaac
    13921 ctgaaattag tttagctatc gtactctttc cgcttcctga ttttcctact aatgcataaa
    13981 ttcttttttg ttctaaaact aagttgaaat tttctaaaac acactcttct ttgtatgaaa
    14041 agctgacatt ttcaaatgca atgtcacaat ttttaatctg tgtctcgttc ccatatttta
    14101 gttggtcttg cttcatttct aaataaaggg agtctagtgt ttcgactgca tatcttgctt
    14161 caaacaagtg catacttaca tacattattc tcatgaaaga aacaaaaata attccactta
    14221 aaaaaaacaa catcaacaag tcaacagcta atatcttggg agtggtaaga gaagttataa
    14281 aaaaggttat aggaactatc aaaatgcaaa ctatgccaaa aaatagccat tgaaaaagaa
    14341 caaaaggtgt tttcccactc aaagaatact tatatgcaaa cttagcataa tcgttaattg
    14401 ctttattcaa ggctttaaat gatgttactt tagcaccaaa tatctttata acttgaattc
    14461 ctcggatata ttctaccgtt tcagagctta acacatctaa cgattcttga tatttttgaa
    14521 taaaatttgt attctctgtc attttcttta acaagaatac accaattact aacatggcga
    14581 ttagaaccaa tccaatttta aaattaatga aaaagcctaa ggcaactgat aaaacaggtg
    14641 ttactatggc ttgagcacta tctggaatca agtgagcaat tgccatatgt gttttagccg
    14701 cgttgtcatc aattgtcttt cgaatatatc ccgaagaatt taaatcaaaa aaacgaaaac
    14761 ttgcttctgt taaaccgcta attccctttt ttctcaaatt agtctctaag cgaaacccaa
    14821 ggatatgaga aaataagcca gaaaaaatat aaaataaagc tcctaaagtt aaccaagcaa
    14881 cagtttgaac cgcataactc ttagctaaat attcatctcc tacaataatt agagacttaa
    14941 gaaatttgta aatactgtaa tatccataga ctgttaatac gacagaaaaa tcagaaaata
    15001 aagtggctaa ccatccgtag tatttcattt tagggacata actaaataat tttttgtata
    15061 ctttcatttt ttcctccccc gcattcaatt tcttctctta ttcgtttaca actgttaatg
    15121 ctttccgtaa tagcgtaaat tagagatgta caaacagata gaaggtaaac tacgttctat
    15181 tttttgtatt tttttaagac ttttcttcca atcaatacac caatcataga taaacttgct
    15241 acaactaaca ctgaaatgat tccccatata cctaccgcat agtggatcat tgcatccatt
    15301 gttgcagcag attgtccttt atctatccaa tcttgacgaa aacgatctgt aaagaaccat
    15361 ataggaatcc actgtccggc agcactgcct aattgcatta gagcccaaga cgcaacttga
    15421 ggaattgctc gatcatatcc aaatacagat agaataatat cagctaagat cgccatacta
    15481 atcgaactga taaaccaagg taagtacgcc ccgcccatta acgtaaaaaa taacaataaa
    15541 acaattgtgt aaatagtaaa aattcctttt ctagggtagt tatagctaat ataaacaaat
    15601 atgattccag ataataatcc aaaaatccct ggggatatgc tgtgaccaaa cgccccacca
    15661 atactactaa ccattattga aaaaaagtaa attactaggg aaataactgt agctaaacca
    15721 ataaaaatat aatcttttgt tttcatatat attctcctca attctatttc gttatgtcat
    15781 taaaaatctg ttctatcaaa gttgaatctt ctactctaag ttttatatct ttttttattc
    15841 caccattttt taaataaata attctattgc atgttttata aagaaattcc ggatcatgag
    15901 tggctataac tactgcaccc ttttctttta agtctttaat aaggtcagca atcctttcca
    15961 tattaatata atccaaccca cttgtaggtt catcaaatag aaataaatta gtttttgaca
    16021 atgaagctat agaaaccaat aatctttgtt tttctccacc ggataaatca aacggtaatt
    16081 gatctttcat tttataaagt tccatttttt ttaaaatttt ttcttgctga tctttactaa
    16141 ctatttcatt ccccagggct aactcgctcc tcactgattc tgtgaaaaat tggtaatcca
    16201 tttcttgcat tactaaaaac ggcgatgaca aatttttttt attttcgatt atctttcctt
    16261 tggtagggcg aataatcttc atgagtattc ttagtaaggt tgttttcccc acaccgtttt
    16321 tccctaccaa accaataaca tctccaactt tgacatcaaa atttatgtct tttagaatat
    16381 tttcataagt aatttcttca acttttaata catctgcact taccttttcg atatagggaa
    16441 cttcaatcga actattaaaa atgtcaaatt tccttaatgc gttattgttt tcagttttta
    16501 acaactgaat agttgtagtt tttacagttc tatttttaac aaatagaact tgatcaatta
    16561 attctttcaa atagtaaaaa cgatgttcag ctataacaat agtaaatcct ttatttttta
    16621 aatcacaaag taagtcagca agtttcttag tcgctttgaa gtccaaattt gaagacggtt
    16681 catccaatat aattaattta gagtttagcg ataaactaca tccaatagaa attttctgcc
    16741 gttcaccact tgatagcgaa aaaatgtttt tatctaatat atttgaaaga tctaataatt
    16801 cagctaattc attgattctt ttatccatat gctcttttgt aaatccaaag ttttccatcg
    16861 aaaatactaa ctcactcgtt gtatttgttg taaagaattg tcctctagga tcttgactta
    16921 cgtagccaat attttttgat atactttctt gtgttaagga ttgtagcgag ttattttcaa
    16981 ataaaatttc cccaaccaat tttccgtcat aaagtcttgg aataagtcca ttcattaact
    17041 ttaatagtgt ggatttccca ctcccagaag aaccagtaat caatgtaaga ctaccttttt
    17101 ttattgaaaa attaaggtca acaagcgctt gttccttaac atccttatat gaaaaagaaa
    17161 cattgttaaa ttcaaacaat tctttcacct caaatcaaaa tacttaagaa aaaaatagta
    17221 acggaaaaca ggatgatata gtctaataag ctcatgtttg ttttatagta agaacttctt
    17281 ttcacaggag attctatccc ctttgttatt gcattagcgg tcatttcttc agcaatcata
    17341 gttgcacgta taagaacggg aactaacaga aattccaaat attgcagagg ctgaaaaaaa
    17401 gacaagcgaa tgtttctcat ttttaaagat tctttaatca ttcttatttc agaacgataa
    17461 gtcggaaaga atctgatcac tactgtaata cttaacatta tttttttcgg taaatgtatt
    17521 ttttctaaag aggataataa ttcattgcta gtatagacac taaccaacaa ccatgagatc
    17581 attacgaccg gcaacattcg aaatacaata tataaggatg tcccaaaaaa tatagtaaaa
    17641 aactctatct tgatagcatc aataattttc attactaaaa acagaactga ataaatcaag
    17701 atgaaataaa tacatgtctt tattttacga aacatcaata ctaaaactgt agcaataatg
    17761 aaacacccca cttgaaatat atttcccttt cctaaaaaaa taatgaccgg aaaaaaaata
    17821 tttaaagtaa tcaaggttaa cggattgatt tttgacactc tttcacctcc aaaaaataag
    17881 atcgcactgt tatcttaagc tgataaaaat gcaccgttat tcagataaca gtgcgatctt
    17941 atcaaaaagc ataactgaga acaattctca atgcaagctt ttttttaatt aactcagtaa
    18001 ttcaatccac ccaggaacag aaaattgata caatcttctg gttaatagca tagtcttttc
    18061 ttttgaatag ctatgcttca atatatcata gaatgtagcg tagaatgagt aaatgtagaa
    18121 gtggatttct tcttcattaa agactaaatt ttgattgatc attccgatag tctttaactt
    18181 atctagacaa cagactgtct tttttgtcac aaatgatgta attttttcaa caatatcttg
    18241 atatttggtt ccagctgatt ggaataaaac caaatcgaat atacgtttat tctcaaaaat
    18301 ataattaata aatggatcta attcattgaa gttctctctc caact
//
LOCUS       DAZKKZ010000058        17835 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.059, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000058 DAZKKZ010000000
VERSION     DAZKKZ010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17835)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17835)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17835
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.059"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            124..936
                     /locus_tag="ACG8LA_002162"
     CDS             124..936
                     /locus_tag="ACG8LA_002162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HFQ0204446.1"
                     /translation="MLRFFPQKNKYIQEKSEFQFNTDGPIPQHIAIIMDGNGRWAQNR
                     RLPRVAGHKEGMETVKKVTKKASRLGVKVLTLYAFSTENWKRPKDEVSFLMQLPVDFF
                     DTFVPELIKENVKVHVMGYENVLPEHTQDAVRRAIEQTKNNTGMVLNFALNYGSRAEI
                     VTAVQEIAEEVAKGEIHAEEIDDELIAKHLMTGFLPKELQDPELMIRTSGEERISNFL
                     LWQIAYSELYFTKALWPDFDGAHLEEAIASYQNRDRRFGGVKKTEDEKGDQS"
     gene            933..1733
                     /locus_tag="ACG8LA_002163"
     CDS             933..1733
                     /locus_tag="ACG8LA_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HFQ0204447.1"
                     /translation="MKQRVITAAVALVLFIPIIWIGGIAVELTAAILAVVGVYELFRM
                     KGLTLLSFEGVLSAVGAVLLVLPKERWFFFLPENVSTFMLFYLIVMILLGTSVISKNT
                     YTIDEAGFPVLVSLYVGIGFQNFVNARTESLAVLIFGLFIVWATDIGAYMVGRRYGQH
                     KLSPDISPNKTIEGALGGIGSAVVVAFLYLLLYPAKELFNHGMFVMLLMTIIFSAVGQ
                     FGDLVESAIKRHYDVKDSGNILPGHGGILDRFDSLLFVFPIMHLFGII"
     gene            1894..3162
                     /gene="rseP"
                     /locus_tag="ACG8LA_002164"
     CDS             1894..3162
                     /gene="rseP"
                     /locus_tag="ACG8LA_002164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HFQ0204448.1"
                     /translation="MKTILTFIIVFGILVIVHEFGHFFFAKRSGILVREFAIGMGPKI
                     YGHQAKDGTTYTLRLLPIGGYVRMAGNGDDETEMAPGMPLSLLLNSDGIVEKINLSKK
                     IQLTNAIPMELSRYDLEDELTITGYVNGDETEVVTYPVDHDATIIENDGTEIRIAPKD
                     VQFQSAKLWQRMLTNFAGPMNNFILAIVLFIILAFMQGGVQVTNTNRVGEIMPNGAAA
                     EAGLKENDEVVSVDGKEIHSWNDLTTVITKNPGKTLDFKIEREGQVQSVDVTPKSVES
                     NGEKVGQLGIKAPMNTGFMDKIIGGTRQAFSGSLEIFKALGSLFTGFSLDKLGGPVMM
                     YQLSSEAANQGVTTVISLMALLSMNLGIVNLLPIPALDGGKLVLNIFEGIRGKPLSQE
                     KEGILTLAGFGFLMLLMVLVTWNDIQRFFF"
     gene            3230..4939
                     /locus_tag="ACG8LA_002165"
     CDS             3230..4939
                     /locus_tag="ACG8LA_002165"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0002161 - aminoacyl-tRNA editing activity
                     [Evidence IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0004827 - proline-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006418 - tRNA aminoacylation for protein
                     translation [Evidence IEA];
                     GO_process: GO:0006433 - prolyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HFQ0204449.1"
                     /translation="MRQSKMLIPTLREVPNDAEVLSHQILLRAGYIRQVSAGIYSYLP
                     LANRVLEKLKRIMREEFEKIGAVEMLMPAILPAELWEESGRYETYGPNLYRFKDRNDR
                     KMILGPTHEETFTDLMRNEINSYKKLPLNLYQIQPKYRDEKRPRFGLLRGREFIMKDA
                     YSFHATEESLDETYKDYEKAYTEVFKRCGLEFRSIIGDGGAMGGKDSKEFMAISEIGE
                     DTICYSTESDYAANLEMATSYYVSKKSHETQLELEKVATPNVKSIDEVADFFSVEPQK
                     IIKSVLFIADEQPVLVLVRGDHEVNDVKLKNFLSADFLEEATEEEAQKYLGAEFGSVG
                     PVGVSDDVKVYADRYVQDLANAITGANETGFHYKNVNPKRDFTVLSYEDLRFVQEGDP
                     SPDNNGVLAFTRGIEIGHIFKIGTRYSESMGATVLDENGREKFVIMGCYGIGVSRLLS
                     AIVEQHSDEQGINWPKGIAPFDLHIVQMNLKDEYQTSLTNELEEAMTKAGYEVLVDDR
                     NERAGVKFADSDLIGCPIRITVGKKAVDGIVEVKIKKTGEMVEVRKEELANTLPILLN
                     QGE"
     gene            5151..9503
                     /locus_tag="ACG8LA_002166"
     CDS             5151..9503
                     /locus_tag="ACG8LA_002166"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HFQ0204450.1"
                     /translation="MSEKRDLFEKLLEQIQLEEAEKNHPLLTAGEMDSVVVHRKSRLW
                     EFTLHFSKILPIMLYRSLTQHLTIAFKDIAQVKLNILADDQTFDEQLLQDYWAQALEN
                     QQCDTPLAQQVLKTQVPVIKDRKVILPIDSTGAISYLKQQYLPLVEELFVSYGFPKFR
                     IEPEVDEQQAERVLKLFEERKQEQAEAFMKQAAESLVVHEQKKKERKEQSPALEGPIQ
                     LGRNIPADEPTTPMISIVEEERRVTLEGYVFDKEVRELRSKRKILTLKITDYTSSFIV
                     KKFSNGEKDEQVFDAISVGSWLKVRGSIQEDTFVRDLVMNAQDIIEVKHTPRKDYAPE
                     GEKRVELHVHSNMSTMDATNSISDLVAQAGKWGHRAIAITDHGGAQAFPEAHSAGKKA
                     GVKILYGVEANVVDDGVPIAYNDAHEALSEATYVVFDVETTGLSAVYDTIIELAAVKM
                     YKGNVIESFDEFIDPGHPLSRTTVDLTGITDEMVRGSKSEEEVLRMFLEFSKDTILVA
                     HNAAFDMGFLNTSYARYGIPEAANPVIDTLELARYLYPQFKRFGLGVLSKKFGVSLEQ
                     HHRAIYDAEATGHLAWIFVKEAMDNHNMLYHDQLNEHIGEGDSYKRARPFHVTILAKN
                     QAGLKDLFKLISMSNVEYFERVPRIPRSQLKKMRENLLIGSACDKGEIFEAMMQKGVE
                     EARNRAKFYDYIEVMPKAVYAPLIEQELVKNEHDLEEIIQNLVEIGKSLDKIVVATGN
                     VHYLNEEDAIYRKILINSMGGANPLNRHSLPDVHFRTTDEMLTAFHFLGEETAKEIVV
                     ENTNKIADICEEVIPVKDELYTPKIPGSEDEISELSYTKAKQMYGDPLPEIIQKRLEK
                     ELNSINGNGFSVIYLIAQKLVHKSNEDGYLVGSRGSVGSSFVATMTGITEVNPLAPHY
                     YCPECQYSEFFEDGTYGSGFDMPEKQCPKCGARLNKDGHDIPFETFLGFHGDKVPDID
                     LNFSGDYQAEAHNYTKVLFGEDYVYRAGTIGTVADKTAYGYVKGYERDNNLQFRSAEV
                     DRLAKGATGVKRTTGQHPGGIIVIPDYMDVYDFTPIQYPADDQNSEWKTTHFDFHSIH
                     DNVLKLDILGHDDPTVIRMLQDLSGIDPQTIPTDDPEVMRIFAGPEVLGVSQEQIYSK
                     TGTLGIPEFGTRFVRGMLEETHPTTFAELLQISGLSHGTDVWLGNAEELIRRGDATLA
                     EVIGCRDDIMVYLIHAGLDSGMAFKIMETVRKGQWNKIPDELRETYLSAMKENNVPDW
                     YIDSCSKIKYMFPKAHAAAYVLMALRVAYFKVYFPILYYCAYFSVRADDFDLVSMCKG
                     KDAVKQAMKEITDKGLDASVKEKNQLTVLELANEMLERGFKFGMIDLYKSDAVNFVIE
                     GDTLIAPFRAVPSLGTNVAKQIVEARKDGPFLSKEDLATRGKVSKTLIEYMNDNGVLK
                     DLPDENQLSLFDML"
     gene            9647..10120
                     /gene="rimP"
                     /locus_tag="ACG8LA_002167"
     CDS             9647..10120
                     /gene="rimP"
                     /locus_tag="ACG8LA_002167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0042274 - ribosomal small subunit
                     biogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HFQ0204451.1"
                     /translation="MSSVVETVTEMVTPILDEQNFELVEVEFVKEGKSWFLRVFIDKE
                     GGIDIEECAFVSEKLSEKLDAADPDPIPQAYFLEVSSPGAERPLKKESDYEKALGDYV
                     HVSLYQPVDGEKQYEGFLQSFDAEQLTLKIRIKTREKELTFDRKNIAKARLAIQF"
     gene            10144..11319
                     /gene="nusA"
                     /locus_tag="ACG8LA_002168"
     CDS             10144..11319
                     /gene="nusA"
                     /locus_tag="ACG8LA_002168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor NusA"
                     /protein_id="HFQ0204452.1"
                     /translation="MSKEMLNALDALEAEKGISKEIVIDALEAALVSAYKRHYGQAQN
                     VEVEFDQKKGKIHVYAVKEVTEEVMDSQLEVSLKDALLINPAYEIGDTIRFEVTPKDF
                     GRIAAQTAKQVILQRVREAERTIIYNEFSAYEKDIMQGIVERQDKRYIYVNLGKIEAV
                     LSKQDQMPNEFYQPHDRIKVYVSRVENTSKGPQVFVSRSHPDLLRRLFEQEVPEVYDG
                     IVEIVSIAREAGDRSKVAVRSNDPNIDAVGTCVGPKGQRVQAIVNELKGENMDIVEWN
                     EDPAVFIANALNPAQVMDVIFDETNPKACTVVVPDYQLSLAIGKRGQNARLAAKLTNH
                     KIDIKSESDMTEFYENQEQQKETEELHDEAIVQSDLTDDEYETIAFNNETVEEKPEA"
     gene            11341..11634
                     /locus_tag="ACG8LA_002169"
     CDS             11341..11634
                     /locus_tag="ACG8LA_002169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HFQ0204453.1"
                     /translation="MKQRKIPLRKSVVSGEMKPKKEMVRITRSKEGEVSIDPTGKMPG
                     RGAYVSLEPEEVQQAWDKKILDRVLETTLTDEFYQELLDYVTHQKARKELFGK"
     gene            11631..11942
                     /locus_tag="ACG8LA_002170"
     CDS             11631..11942
                     /locus_tag="ACG8LA_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HFQ0204454.1"
                     /translation="MNTVNRQKAMNLIGLAMRAGKLITGEELTIAEIRKQKAKLVFVA
                     TDASENTRKKIKDKSSYYEVPCFELFSEAEITQMIGKPRKVFGIMDAGFAKKTKELIE
                     G"
     gene            11955..14261
                     /gene="infB"
                     /locus_tag="ACG8LA_002171"
     CDS             11955..14261
                     /gene="infB"
                     /locus_tag="ACG8LA_002171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HFQ0204455.1"
                     /translation="MGNKRIYELAKELKKSSKDVVEKAQQLGIDVKNHMGAITSSDEK
                     KLQQAFKNPSTKQQAAQQASRKPANQQPNDQRKKETTNNQQKNKNNRSYQDRGQGSGQ
                     VNQGKKPTTNQNNTGNTSSQNRQGTSQGGNQNRTNNNNKPNNNNRGKFNNNNRNRYNK
                     KGKKGKQQQSTKPAVPPRKFRELPDVLEYTEGMNVADIAKKIHREPAEIIKKLFMLGV
                     MVNQNQALDKDTIELLATDYGMEPQEKVQVDIADIDKFFEAEEVDPDKLVSRPPVVTI
                     MGHVDHGKTTLLDTLRHSRVTSGEAGGITQHIGAYQIDIDGKPITFLDTPGHAAFTSM
                     RARGASITDITILVVAADDGVMPQTVEAINHAKAAGVPIIVAVNKIDKPGANPQHVMQ
                     ELSEYELIPEAWGGETIFVEISAKFGQNIEELLEMILLVAEVEDLKADPTQRAIGTVI
                     EARLDKGKGPVSTLLVQEGTLHVGDPIVVGNTYGRVRVMTNDLGRRDKEAGPATPVEI
                     TGLNDVPQAGDRFVVFEDEKTARAAGEERAKRALLENRAATSRVTLDNLFESLKEGEL
                     KEVNVIIKADVQGSAEALAASLKKIDVEGVRVKIVHSAVGAINESDVTLAAASNAIII
                     GFNVRPTPQAKVQADTEEVDIRLHRIIYKAIEEIETAMKGMLDPEFEEKITGQMIVRE
                     TFKVSKVGTIAGAYVTEGYIRRDSGVRVIRDGIVIYEGQLASLKRFKDDVKEVKMGYE
                     CGAMIEKFNDIKVDDVIEGFIMEEVKND"
     gene            14288..14635
                     /gene="rbfA"
                     /locus_tag="ACG8LA_002172"
     CDS             14288..14635
                     /gene="rbfA"
                     /locus_tag="ACG8LA_002172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HFQ0204456.1"
                     /translation="MANYRDRRVGQEILKEVNDILRKKVRDPRVENVTITDVKVTGDL
                     QQATIYYSILSDLASDKKKAQDGLNKASGLIRRELGHNLSIYKTPELFFELDESVVYG
                     NHIDELLRDLNKD"
     gene            complement(14743..15247)
                     /locus_tag="ACG8LA_002173"
                     /pseudo
     CDS             complement(14743..15247)
                     /locus_tag="ACG8LA_002173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035543.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            15412..17775
                     /locus_tag="ACG8LA_002174"
     CDS             15412..17775
                     /locus_tag="ACG8LA_002174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoketolase"
                     /protein_id="HFQ0204457.1"
                     /translation="MDYSSKEYFDKMTAWWRAANYLSVGQLYLKDNPLLRRTLKPEDV
                     KKHPIGHWGTIPGQNFIYVHLNRVINKYDLNMFYIEGPGHGGQVMVSNAYLDGSYTEI
                     YPEVTEDETGMQKLFKRFSFPGGIASHAAPETPGSIHEGGELGYSLSHAVGAVLDNPE
                     VISAVVIGDGEAETGPLAGSWFSNVFINPVIDGAVLPILHLNGAKIANPTILARKSDG
                     ELANYFNGLGWEPFFIEGNDPEKLNPVMAEKMDQAIEKIKSIQKEARLKTATDVVMPK
                     WPVLIVRTPKGWTGPKEWDGEPIEGTFRAHQVPIPVDQEHMDHADALLRWLKSYEPEK
                     LFDAQGRILEEIREIAPTGDQRMAKNPITNGGIDPRPLIMPDWKKYTLQFEKPGSVKA
                     EDMTELGKFVREIIEKNPENFRIFGPDETKSNRLNQVFKTTNRQWMEKIEPENDEWLS
                     PSGRVIDSQLSEHQDEGFLEGYVLTGRHGFFASYESFLRVVDSMLTQHFKWIRKSHDL
                     SWRKDYPSLNLIASSTVFQQDHNGYSHQDPGILTHLAEKKAEFIREYLPADANTLLAV
                     MDKAFRSSEKINLIISSKHPRAQFYSAEEAAVLVNEGLKIIDWASTAKEEEPELVIAA
                     AGTESNLEALAAVTLLLEEFPKLKIRFINVVDLLKLRHPSQDPRGLSDEEFDQYFTKD
                     KPILFAFHGYETLVRTIFFDRHNHHLMIHGYKENGDITTPFDMRVVNELDRYHLAKDA
                     ALKIKGSQAEDFAEKMDQKLQEHQNYIRENGIDLPEVLDWKWKNLDQ"
BASE COUNT         6096 a         3154 c         3920 g         4665 t
ORIGIN      
        1 attaaaaaaa gaaaaaatta ttcagttttt aaataaaaaa acaatgattt cataggaaaa
       61 acagttagat attgctataa tacttaagat agtgggaatc ttttaagtat aggaggaaaa
      121 agaatgttac gtttttttcc gcaaaaaaac aaatatattc aagaaaaaag cgaatttcaa
      181 tttaataccg atggaccaat tcctcagcac attgccatca tcatggacgg caatggtcgt
      241 tgggcgcaaa accgtcgttt gccacgagtt gctggccata aagaaggcat ggaaacagta
      301 aagaaagtca caaaaaaagc atcaaggctt ggagtgaaag tgttgacgct ttatgccttt
      361 tcgactgaaa actggaagcg accaaaagat gaagtaagtt ttctcatgca actacctgtc
      421 gacttctttg atacgttcgt accagaattg attaaagaaa atgtcaaagt tcatgtcatg
      481 ggttatgaaa acgtattgcc agaacatacg caagatgctg taagacgtgc aattgagcaa
      541 acaaaaaaca atactggaat ggtattgaat tttgctttga attatggaag tagagcagag
      601 atcgtgactg ctgtccaaga aattgccgaa gaagtagcaa aaggagaaat acacgcagaa
      661 gaaatcgatg atgaattgat tgctaagcat ttaatgacag gtttcttgcc taaagagtta
      721 caagatcctg agctgatgat ccgtacaagt ggagaagagc gaattagtaa ttttctgtta
      781 tggcagatcg catatagtga gctgtatttt acaaaagcgc tttggcctga ttttgatggt
      841 gcgcatcttg aagaagcaat cgcctcttat caaaatcgag accgtcgatt cggcggtgta
      901 aaaaaaacag aagatgagaa aggggatcag tcatgaaaca acgtgtgatc acagcagctg
      961 tggcgctagt cttgtttatt ccgattatat ggatcggagg catagcggtt gagcttacag
     1021 cagcaatctt agcggtagta ggagtttacg agctgttccg gatgaaagga ttgacactct
     1081 taagttttga aggagtttta tccgccgttg gtgcagtgtt acttgttttg ccaaaagaaa
     1141 gatggttttt ctttcttcca gagaatgtaa gtacatttat gttattttat cttatagtta
     1201 tgattctttt aggaacatca gttatttcta aaaatacgta tacgattgat gaagcaggtt
     1261 ttcctgtgct tgtcagcttg tatgtgggaa taggtttcca gaattttgtc aatgcacgaa
     1321 cagaaagctt ggctgttttg atatttggtc tatttattgt ttgggcaact gatatcggag
     1381 catatatggt tggtcgacgt tatggtcagc ataagttaag tcctgatatt tcgcccaaca
     1441 aaacgattga aggtgcgctc ggtggtatcg gtagtgctgt tgtagtcgca tttctttatt
     1501 tattgctata cccagcaaaa gaactattca atcatggtat gtttgtcatg cttctgatga
     1561 cgattatttt ttcagcagtc ggacaatttg gtgatttggt cgaatctgca atcaaacgtc
     1621 attatgatgt gaaagactcg ggaaatatct taccaggcca tggtggaatc ttagaccgtt
     1681 tcgacagttt gctgtttgta tttcctatca tgcatttatt tggcattatt tagtaagtat
     1741 acctgcgttt ctttgtgaat ttcataaaag acgcaggttt ttatttttca ttatattgat
     1801 actattggtg tctttggtat actatggtaa aattatagtg ttttatcgtt gttttataaa
     1861 aaacacaaaa aacaagtaaa ggagaaaaaa gctatgaaaa cgattctgac atttatcatc
     1921 gtttttggta tattagtgat tgttcatgag tttggtcatt tcttctttgc gaaacgatca
     1981 ggaatcctcg tccgcgaatt tgctatcggt atgggtccga aaatttatgg gcatcaagca
     2041 aaagacggga caacatatac gcttcgccta ttacctattg gcggttatgt tcgaatggca
     2101 ggcaatgggg atgatgaaac agaaatggca ccaggaatgc ctctttctct tttactaaat
     2161 tctgacggca tcgtagagaa gataaattta agtaagaaaa tccaattgac aaatgctatc
     2221 ccgatggaat tgagccgtta tgatttagaa gatgagctga ctatcactgg ttatgtgaat
     2281 ggagacgaaa cagaagtagt aacctaccct gttgatcacg atgcgacgat tattgaaaac
     2341 gacggaacag aaatcagaat tgcgccaaaa gacgtacagt tccaatcggc taaattgtgg
     2401 cagcgtatgc tgaccaactt tgctggaccc atgaataact ttattttggc aatcgtgtta
     2461 ttcatcattc tggcatttat gcaaggtggt gttcaagtga cgaacactaa tcgcgtagga
     2521 gagatcatgc ctaatggagc tgcggcagaa gcaggcttaa aagaaaatga tgaggtagtc
     2581 agtgtggacg gaaaagaaat ccattcatgg aatgatctga caacagtcat tacgaaaaat
     2641 ccaggtaaaa cattagactt taagatcgaa cgagaaggtc aggtgcaatc tgtcgacgtg
     2701 acaccgaaat ctgtagagtc aaatggcgaa aaagttggcc aacttggtat aaaagcccca
     2761 atgaatacag gttttatgga taagatcatt ggagggacgc gtcaagcttt cagcggttca
     2821 ttggaaattt tcaaagcctt aggatcacta tttacaggtt tcagtttaga taaattaggc
     2881 ggacctgtca tgatgtacca attgtcttca gaagcagcaa atcaaggtgt aacaactgtt
     2941 attagtttga tggcgcttct ttcaatgaat ctcggaatcg tcaatctgct tccgattcct
     3001 gccttagatg gcgggaaatt agtcttgaat atttttgaag ggattcgcgg gaaaccatta
     3061 agtcaagaaa aagaaggaat attgacatta gctggctttg gatttttaat gttgttgatg
     3121 gtgctagtta catggaacga tattcaacga ttctttttct agaaaaagtt gacaaatagg
     3181 gtataataac aaacgataac tattttgagg aaataaagga gtatatagaa tgagacaatc
     3241 aaaaatgttg attccaacat tacgcgaagt tccaaatgat gcagaagtat taagccatca
     3301 aatcttgcta agagctggat atatccgcca agtatcagcg ggtatttatt catatctgcc
     3361 attagcaaat cgtgtattgg aaaaactgaa acgcattatg cgggaagaat ttgaaaaaat
     3421 cggagcggta gaaatgctga tgcctgccat cttgccagca gaactttggg aagaatccgg
     3481 gcgttacgaa acatatggac caaacttgta tcgtttcaaa gaccgcaatg atcgaaaaat
     3541 gatccttgga ccaactcacg aagaaacttt tactgatttg atgcgtaatg aaatcaattc
     3601 atataagaaa ttacctttaa atctttatca aatccaacct aaatatcgtg acgaaaaacg
     3661 acctcgcttc ggtttgcttc gcggaagaga gtttatcatg aaagatgcat attctttcca
     3721 tgcaacggaa gaaagtttgg acgagacata taaagattac gaaaaagcct ataccgaagt
     3781 attcaagcgt tgtggcttag aatttcgctc gatcatcgga gacggcggcg caatgggcgg
     3841 gaaagactca aaggaattca tggcgatctc agaaatcggg gaggatacga tctgttattc
     3901 gactgaaagt gattatgctg caaacttgga gatggctaca agctactatg tatcaaaaaa
     3961 atcgcatgaa acacagcttg aattggagaa agtagctaca cctaacgtaa aatcaattga
     4021 cgaagtagca gatttctttt ctgttgaacc tcaaaaaatc atcaagtctg tattgttcat
     4081 tgcggatgaa caacctgtcc ttgttttggt acgtggagac catgaagtca atgacgtaaa
     4141 actgaaaaac tttttatctg ctgacttttt agaagaagca acagaagaag aagcacaaaa
     4201 atatctaggt gctgagtttg gttctgtcgg accagtcggt gtttcagatg acgtaaaagt
     4261 atatgcagac cgttatgtcc aagatttagc gaatgccatt actggagcga acgaaacagg
     4321 attccactat aaaaatgtga atccaaaacg cgatttcact gtgctttctt atgaagatct
     4381 tcgttttgta caagaaggag atccttcacc agacaacaac ggtgttcttg cctttactcg
     4441 aggaatcgaa atcggacata tattcaaaat cggcactcgt tacagtgaat ctatgggagc
     4501 aactgtacta gacgaaaatg gacgagaaaa atttgtgatt atgggctgtt atggtatcgg
     4561 tgtaagtcgt ttattatcag caatcgtaga acaacattca gatgaacaag gaatcaattg
     4621 gccaaaagga attgcgccat ttgatctgca tatcgtccaa atgaatctaa aagacgaata
     4681 ccaaacaagc ctgacgaatg aactagaaga agcgatgaca aaagctggct atgaagtact
     4741 ggttgatgac agaaatgaac gcgcaggagt gaaattcgcg gattctgatt tgattggctg
     4801 tccaatcaga atcactgtcg gtaaaaaagc agtggatgga atcgtagaag tgaaaatcaa
     4861 gaaaactggc gaaatggttg aagtacgtaa agaagaattg gcgaatactt taccaatcct
     4921 cttgaaccaa ggcgaataat aagcgttaaa acacagaaaa taaaaatagc tgaatcagct
     4981 gtttttgaca atctgatgat tcgcttttaa aattggaact gcgatttgaa tcgcagttcc
     5041 aattttttaa tgtaaaactc agaaaaaacg agtatactaa aaggtactga aaaagaagag
     5101 gataagatgc gatcaattgc attgtttctc atcagaaagg gcgtatatct ttgtcagaaa
     5161 aacgagattt atttgaaaaa ctgttggaac aaatccaact agaggaagca gaaaaaaatc
     5221 atccactgct tactgctggt gaaatggata gtgtagtggt ccatcgtaaa tcgcgtttat
     5281 gggaatttac gctacatttt tccaaaattt tgcctattat gctatatcgg tcattgactc
     5341 agcatctgac tatcgctttt aaagatattg cacaagtcaa actgaatatc ttagcagatg
     5401 accagacatt cgatgaacag ctcttgcaag attactgggc ccaagctttg gaaaatcagc
     5461 aatgcgatac accactagca cagcaagtat tgaaaacgca ggtacctgtg ataaaagatc
     5521 gtaaagtcat cttgccaatc gacagtacag gagctatttc ttatttgaag caacaatact
     5581 tgccattagt agaagagttg ttcgtcagtt acggattccc aaaatttcgt atcgaaccag
     5641 aagtggatga gcagcaagcg gaacgtgtat tgaaactttt tgaagaacgc aaacaagaac
     5701 aggcagaagc ctttatgaag caagcagctg aaagtctagt tgtccacgaa caaaagaaaa
     5761 aggaaagaaa agagcaatcg ccagctcttg aaggacccat ccagctagga cgaaatattc
     5821 cagccgatga accaacgaca ccaatgatca gtatcgttga agaagaacga agagtcacac
     5881 ttgaggggta cgtattcgac aaagaagtca gagaactacg ttcaaaacgc aagatcttga
     5941 ctttgaaaat cacagattat acttcatcat ttatcgtcaa aaaattctcg aacggcgaaa
     6001 aagatgaaca agtatttgat gcgatcagtg tcggtagctg gttaaaggta cgaggaagta
     6061 ttcaagaaga tacgtttgtc cgtgatttgg tcatgaatgc gcaagatatc atagaagtca
     6121 aacatacacc tcgcaaagat tatgctcctg aaggggaaaa acgagtagag cttcatgttc
     6181 atagcaatat gagtacgatg gatgcaacaa acagcatctc tgatcttgtg gcacaagcag
     6241 gaaaatgggg acaccgagct atcgccatta cagaccatgg tggtgcgcaa gcctttccgg
     6301 aagcacatag tgctggaaaa aaagcaggtg tgaaaatctt atacggcgtg gaagcgaatg
     6361 tcgtagatga tggtgtccca attgcttata atgatgcaca tgaagcattg agtgaagcca
     6421 catacgtcgt atttgacgtg gaaacgacag gattgtctgc agtatatgac acgatcatcg
     6481 agctagccgc agtcaaaatg tataaaggaa atgtgatcga aagctttgat gaatttatcg
     6541 atccaggaca tccattgtca cgaacaacgg tagatctgac tggtatcacg gatgaaatgg
     6601 ttcgagggtc aaagtcggaa gaagaagtat tgcggatgtt ccttgaattt tcaaaagata
     6661 caattttggt agcccacaac gcggcttttg atatggggtt cttgaatact agctacgcaa
     6721 ggtatggtat tcctgaagcg gccaatccag tcattgatac gttggaatta gctagatatc
     6781 tgtatcctca attcaaacgt ttcggattag gtgtgttatc taaaaagttt ggtgttagct
     6841 tggaacagca tcaccgagca atctatgatg ctgaagcaac tggtcactta gcatggatct
     6901 ttgtgaaaga ggcaatggac aatcataaca tgctttatca tgatcagcta aatgagcata
     6961 tcggagaagg agattcttac aaaagggctc gacctttcca tgtaacgatt ttagcaaaaa
     7021 atcaggcagg actgaaagat ttgttcaaac tgatttcaat gtcgaatgtc gaatacttcg
     7081 aacgcgtccc acgaatacca cgctcccaat tgaaaaagat gcgtgaaaat ctattgatcg
     7141 gctcagcttg tgataaggga gaaatattcg aagccatgat gcaaaaaggg gtagaagagg
     7201 caagaaaccg agcaaaattc tatgattata ttgaagttat gccaaaagcg gtctatgcgc
     7261 ctttgatcga gcaagaattg gtaaaaaatg aacatgattt ggaagaaatt atccaaaatt
     7321 tggtagaaat cggaaaaagt ttggataaaa tcgttgttgc aacaggtaat gtacattatc
     7381 tgaacgaaga agatgccatt taccgaaaaa ttttgatcaa ttctatgggc ggagcgaatc
     7441 cgttgaatcg tcatagtttg ccggatgtcc atttccgaac aaccgatgag atgctaactg
     7501 catttcactt tttaggggaa gaaacagcga aagagatcgt agtagaaaat acgaataaaa
     7561 tcgcagatat ctgcgaagaa gtgattccag tcaaagatga actttataca ccgaagattc
     7621 caggttcaga agatgaaata tcagaattga gttacacaaa agcaaaacaa atgtacggag
     7681 atccgttacc tgagatcatt caaaaacgat tagaaaaaga gttgaattct attaatggta
     7741 atggcttctc ggttatttat ctgatcgccc aaaaactagt gcataaaagt aatgaagatg
     7801 gctatctagt aggttcacgt ggctctgttg gctctagctt tgttgcgacg atgacaggaa
     7861 tcactgaagt taatccatta gcccctcatt attattgtcc agagtgccaa tattccgagt
     7921 tttttgaaga tggtacgtat ggttctggat ttgacatgcc agaaaaacaa tgtccaaaat
     7981 gtggtgcacg cttaaacaaa gacggtcatg atattccatt tgagacattt ttaggattcc
     8041 atggagacaa agtgcccgat attgatttga acttctcagg tgattatcaa gcagaagccc
     8101 ataactatac gaaagtattg tttggcgaag actatgttta ccgtgccgga acgattggta
     8161 cagtcgccga caaaacagca tatggctatg taaaaggata cgaaagggac aataatctgc
     8221 agtttcgaag tgcagaagtc gacagattag caaaaggcgc tactggagtc aaacggacaa
     8281 ccggccagca tccagggggg atcatcgtta ttcccgatta tatggatgtc tatgatttta
     8341 cgccgatcca atatccagca gacgatcaaa attcagaatg gaaaacgact cattttgatt
     8401 tccactcgat tcacgataat gtattgaaat tagatattct agggcatgat gacccaactg
     8461 ttattcggat gcttcaagat ttatcaggga tcgacccaca aacgatccct acggatgacc
     8521 cggaagtgat gcggatattt gccggtcctg aagtacttgg agtaagtcag gaacaaattt
     8581 attccaaaac agggacatta ggtattccag aattcggcac tcgttttgtt cgagggatgt
     8641 tagaagaaac gcatcctaca acttttgcag aactactgca aatttccgga ctatctcatg
     8701 gtacagacgt atggttagga aatgcggaag aattgattcg acgaggagat gcgacactgg
     8761 cggaagtaat cggctgtcgt gatgatatta tggtttattt gatccatgct ggattagata
     8821 gcgggatggc atttaaaatc atggaaactg ttcgtaaagg acaatggaac aagatccctg
     8881 atgaattgcg agaaacctat ctatcggcga tgaaagaaaa taatgtgccc gactggtata
     8941 tcgattcttg ttcaaaaatc aaatatatgt ttccgaaagc ccatgctgca gcttacgtat
     9001 tgatggctct tcgtgtcgct tatttcaagg tttatttccc tattttgtat tactgtgcat
     9061 acttttctgt acgtgcagac gactttgatc tagtctccat gtgcaaagga aaagatgctg
     9121 tgaaacaagc aatgaaagaa atcacggaca agggattaga tgcttccgta aaagaaaaga
     9181 atcaactgac agtgctggag ttagccaatg aaatgctgga acgaggattc aaatttggaa
     9241 tgattgattt gtataaatcg gatgccgtta actttgttat tgaaggtgat acgttgatcg
     9301 caccatttag agctgtccca agtttgggaa ccaacgtggc gaaacaaatc gttgaagcaa
     9361 gaaaagacgg tccattttta tccaaagaag atcttgccac ccgcggtaaa gtttcaaaaa
     9421 cattgatcga atatatgaac gacaatggcg tattgaaaga tctaccagat gaaaatcaat
     9481 tatcgttatt cgatatgcta taagcatctg ttttcctgtc tgcttgtaat tttaagcaga
     9541 gtatggtata gttcttatag gtaatgatac taactgtgag tgagcggatt tttcgctcac
     9601 tctttttaat ggaattacgc acttaatttt taaggaggcg aaacttttga gtagcgtcgt
     9661 tgaaacagtc acagaaatgg tgacaccgat tttagatgaa caaaattttg aacttgtcga
     9721 agtcgaattt gtaaaagaag gaaaaagctg gttcttacga gtatttattg acaaagaagg
     9781 cggtatcgat atcgaagaat gcgcctttgt cagtgagaaa ctgagtgaaa aacttgatgc
     9841 agcagatcca gatccgattc ctcaagctta tttcctggag gtatcctccc cgggagcaga
     9901 gcggccattg aaaaaagaaa gcgactatga aaaggcactt ggtgattatg tccatgtctc
     9961 cttataccaa ccagtagatg gcgaaaaaca atatgaagga tttcttcaat catttgatgc
    10021 tgaacagctt acattgaaaa tacgcataaa aacacgagaa aaagaattga cttttgaccg
    10081 aaaaaatatt gcaaaagctc gcttagctat ccaattttaa tcacggagag gaatcagaaa
    10141 aaaatgagta aagaaatgtt aaatgcgtta gacgctttag aagctgaaaa agggatctca
    10201 aaagaaatcg tgatcgatgc tttagaagca gcattggttt ctgcatacaa acgtcactat
    10261 ggccaagcac aaaacgtcga agtggaattt gatcagaaaa aaggaaagat ccatgtctat
    10321 gcggtaaaag aagtaacgga agaagtgatg gattcacagt tggaagtctc attgaaagat
    10381 gcacttttaa tcaatccagc atatgagatc ggtgatacga tccgttttga agtaacacca
    10441 aaagattttg gacggatcgc tgcgcaaacg gctaaacaag ttattttaca gcgtgtacgt
    10501 gaagcagaaa gaacgattat ttataacgaa ttcagtgctt atgaaaaaga catcatgcaa
    10561 ggaatcgtcg aacgccagga taaacgttat atttatgtca atcttggtaa aattgaggca
    10621 gttctttcta aacaagatca aatgccaaat gaattttatc aaccacatga tcgaatcaaa
    10681 gtttatgttt cccgagtaga aaatacgtct aaaggtccgc aagtatttgt tagccgcagc
    10741 catccagacc tattgcgtcg cttatttgaa caagaagtac cagaagtcta tgatggaatc
    10801 gttgaaattg tcagcatcgc ccgtgaagct ggcgatcgtt caaaagtggc agttcgctca
    10861 aatgatccaa atatcgatgc agtcggtaca tgtgtcgggc caaagggaca acgagttcaa
    10921 gcaatcgtca atgaattaaa aggcgaaaac atggatatcg tcgaatggaa tgaagatcca
    10981 gctgtattca tcgcaaatgc attgaatcct gcacaagtca tggatgtgat cttcgatgag
    11041 acaaatccaa aggcctgcac agttgtcgtt ccagactacc aattatcgct agcaatcggt
    11101 aaacgcggac aaaatgcacg tttagctgct aaattgacta accataaaat cgatatcaaa
    11161 tcagaatctg acatgacgga attttatgaa aatcaagaac aacaaaaaga aacagaagaa
    11221 ctgcatgatg aagcaatcgt tcagtcagat ttaacagacg atgaatatga aacaattgca
    11281 ttcaacaatg aaacggtcga agaaaaacca gaagcttaac tttagtaagg aggcaaagag
    11341 atgaaacaaa ggaaaattcc tttacgcaaa tccgtggttt caggtgaaat gaaacctaaa
    11401 aaagagatgg tccgaatcac ccgttcaaaa gaaggggaag tatcgatcga tccaactgga
    11461 aaaatgcctg gacgaggagc gtatgtctca cttgagccgg aagaagtaca acaagcttgg
    11521 gataaaaaaa ttctcgatcg agtactcgaa acaacattaa cagatgagtt ttatcaagaa
    11581 cttcttgact atgtcactca ccaaaaagca cgtaaagagt tatttggaaa atgaatacag
    11641 ttaatcggca aaaagccatg aatctcatcg gtctagcgat gcgcgcggga aaactaatca
    11701 cgggtgaaga actgaccatt gctgaaatcc gcaaacaaaa agcaaaattg gtgtttgtgg
    11761 caaccgatgc aagtgagaat acaagaaaaa agataaaaga taagagttca tattatgaag
    11821 ttccttgctt tgagctattt tctgaagcag aaatcacgca gatgatcgga aaacctcgca
    11881 aggtattcgg aataatggat gccggatttg cgaagaagac caaggagcta attgaaggtt
    11941 aggaaggtga ttgcatgggc aacaaaagaa tctatgaatt agcaaaagaa ctcaaaaaat
    12001 ctagtaaaga cgtcgtggaa aaagcacaac aacttggcat cgatgtgaaa aaccatatgg
    12061 gtgcgattac tagcagtgat gagaagaaat tgcaacaagc gttcaaaaac ccaagcacga
    12121 aacaacaagc tgcacaacaa gcaagcagaa aaccagccaa tcaacagccg aacgatcaac
    12181 gtaaaaaaga aacaacgaac aatcaacaaa aaaataaaaa taaccgcagt tatcaagatc
    12241 gcggtcaagg gagcggtcaa gtgaatcaag gaaaaaaacc aacaacaaac caaaataata
    12301 cgggaaatac cagcagccaa aatcgtcaag gaacgagcca aggcggcaat caaaaccgta
    12361 ctaacaataa caacaaacca aacaataaca atcgcggcaa atttaataat aataaccgta
    12421 atcgttataa taaaaaaggt aaaaaaggca aacagcaaca atcaactaaa ccagctgtac
    12481 caccacgcaa attccgtgaa ttgccagatg tattagagta tactgaaggt atgaacgtag
    12541 cagatattgc gaaaaaaatt catcgtgagc cagcagaaat cattaaaaaa ttatttatgc
    12601 ttggtgtcat ggtcaatcaa aaccaagcac tggataaaga tacgattgaa ctgttagcga
    12661 cggactatgg catggaacca caagaaaaag tccaagttga cattgctgat atcgataaat
    12721 tcttcgaggc agaagaagtc gatccagata aattagtctc acgtccgcca gtagtaacga
    12781 ttatgggaca cgtagaccac gggaaaacaa ccttattgga tacattgcgc cattcacgtg
    12841 taacaagcgg cgaagccggc ggaatcacac agcatatcgg tgcctaccag atcgatattg
    12901 atggtaaacc aatcactttc ttggatacac caggacatgc ggcctttaca agtatgcgtg
    12961 cacgtggagc aagtatcaca gatatcacga tcttagttgt tgctgcagat gatggcgtca
    13021 tgccacaaac agttgaagca atcaaccatg ccaaagctgc aggcgttcca atcatcgtcg
    13081 ctgtaaataa aattgataaa ccaggtgcaa atcctcagca tgttatgcaa gaattaagtg
    13141 agtatgaatt aattcctgaa gcatggggtg gagaaacgat ttttgttgag atctcagcga
    13201 aattcggcca aaacatcgaa gaattgctgg aaatgatcct gttagtcgca gaagtagaag
    13261 atttaaaagc agatccaaca caacgcgcaa tcggaacagt gatcgaagca cgtcttgata
    13321 aaggtaaagg tcctgtgtca accttacttg tccaagaagg aacacttcac gttggtgacc
    13381 caatcgttgt cggtaatact tacggacgtg tccgtgtaat gacaaacgat cttggccgtc
    13441 gcgataaaga agcaggacct gcaacgccag tagaaatcac tggcttgaat gatgtacctc
    13501 aagcaggtga ccgtttcgta gtcttcgaag acgaaaagac agcacgtgca gcgggtgaag
    13561 aacgcgcaaa acgtgcatta ttggaaaacc gtgctgccac aagccgtgtg actttggaca
    13621 acttatttga aagcctgaaa gaaggcgaat tgaaagaagt taacgtaatc atcaaagcag
    13681 atgtacaagg ttcagcagaa gcactggctg catcattgaa gaagattgat gtggaaggtg
    13741 tccgtgtaaa aatcgtccat tcagctgtcg gagcaatcaa tgaaagtgat gtaaccttag
    13801 cagcagccag caacgctatt atcatcggtt tcaacgttcg tcctacaccg caggcaaaag
    13861 tgcaagctga tactgaagaa gtcgatattc gtcttcaccg tatcatctat aaagccatcg
    13921 aagaaatcga aactgcgatg aaagggatgc tagaccctga atttgaagaa aaaatcaccg
    13981 gtcaaatgat cgttcgtgaa accttcaaag tttctaaagt tggtacgatt gcaggtgcct
    14041 atgtaacaga aggatatatt cgtagagata gcggtgtccg tgtaatccgt gacggaatcg
    14101 taatctatga aggccaactt gcaagtctga aacgattcaa agatgacgtg aaagaagtca
    14161 aaatgggtta tgaatgtggt gcgatgattg aaaaattcaa tgacatcaaa gtagatgacg
    14221 taattgaagg atttatcatg gaagaagtca aaaatgacta aaaactgata aaaggaggcc
    14281 aatcattatg gctaactacc gtgatcgccg agtcggtcaa gaaatcttaa aagaagtcaa
    14341 tgatattttg cgcaaaaagg tccgtgaccc tcgtgtggag aacgtaacga tcacagatgt
    14401 gaaagttacg ggggacttac agcaagcaac gatctattac agcattttat ctgacttagc
    14461 atcagataag aaaaaagcac aagatggatt gaataaagca tcaggattga ttcgtcgaga
    14521 gttagggcac aatctaagta tttataagac acctgaattg ttctttgaac ttgatgaatc
    14581 agttgtctat gggaaccata tcgatgaatt gcttcgcgac ttgaacaaag actaatcaaa
    14641 aaatcccgca aatcctgtga aatcaggggt tgcgggattt ttttgttttc attaagacgt
    14701 attacctaag agttccatga ctttagtctg gtagcgtgtc agctaaccaa aaaagagaaa
    14761 aagaaaagta aaaaattcga ctttcttttt tctatagtat ataaattttt gcatatagat
    14821 aaagatcaag ataccgataa cggaagctag attgtaatct attttagtga cagtcaggta
    14881 tagccaagta actagaagat cagtggaacc tgcaccataa aagtttgagt ttgtcggtcc
    14941 gttgacagtt aaaagaaaaa tcacgttgaa gttattgata tttccgatta cgccgcttcg
    15001 atttggtcac gatccaaatt ttggataatc cctgtagaaa ttagcatagt agctgggata
    15061 ccaattcaca tattgacaaa gataacagag acttttacat aaaacggatc aatcaggaaa
    15121 ggaattgctc gatccagccc cagttttcca acaatgtgtt aactggccta gcgtcattca
    15181 gcaaattatg catgatgagg agcgaaatga actgcggaac agccattgtg ataacgacaa
    15241 gttttttgga tcaatgtaaa aaacgtcagc gaaaggaaaa atttcgtggt tttttatacc
    15301 tgttcatttg gctagatata aaatccaaac aaatgaacag aagtgcttat taggtttcaa
    15361 ttgggagtat ctgcgctaga ataagagtaa taatgaaaag gagtgttatg tatggattat
    15421 tctagtaaag aatactttga taaaatgacg gcttggtggc gtgctgctaa ttatctttct
    15481 gttgggcaac tttatcttaa agataacccc ttactgagac gtacactgaa accagaagat
    15541 gtcaaaaaac atccaatcgg tcattgggga acgattcctg gccaaaattt tatttatgtc
    15601 catttgaacc gagtcatcaa taaatatgat ttgaacatgt tttatatcga agggccagga
    15661 cacggcggac aagtcatggt atcgaatgct tatttagatg gaagttacac agagatctat
    15721 ccagaagtaa cggaagatga gacaggaatg caaaaattat tcaagcgatt ttcatttcct
    15781 ggaggcattg cttctcatgc agcaccagaa acaccaggtt ctatccatga aggcggagag
    15841 cttggatact ctctttcaca tgcagtcgga gctgtattag acaatcctga agtaatctct
    15901 gctgtcgtga ttggtgatgg tgaagcagaa accggtcctt tagctggaag ctggttctca
    15961 aatgtcttta tcaatccagt gatagatgga gctgttttac cgatccttca tttaaatggt
    16021 gcaaaaatag ccaacccaac gatcttggca cgtaaatcag atggagaatt agcaaattac
    16081 tttaacggac ttggctggga gcctttcttt attgaaggaa atgatccaga aaaattaaat
    16141 cctgttatgg ctgaaaaaat ggatcaagca atcgagaaaa tcaaatccat ccaaaaagaa
    16201 gctcgcctga agacagcaac agatgtcgtg atgccaaaat ggccagtatt gatcgtacgc
    16261 acaccaaaag gatggaccgg tccaaaagaa tgggacgggg aaccaattga aggaaccttc
    16321 cgagcacacc aagtaccgat tcctgtagat caagaacata tggatcatgc agatgcttta
    16381 ctccgttggc tgaaatccta tgaaccagaa aaattatttg atgcacaagg acgtatttta
    16441 gaagaaatca gagaaattgc gcctactggt gaccaaagaa tggcaaaaaa tcctatcacc
    16501 aatggtggaa tcgatccaag accgcttatt atgccagatt ggaaaaaata tactttgcaa
    16561 tttgaaaaac caggctccgt taaagcagaa gatatgaccg aacttggtaa attcgttcgc
    16621 gagatcattg agaaaaatcc agaaaatttc cgtatatttg gaccagatga aacaaaatca
    16681 aaccgattga atcaagtttt caaaacgaca aatcgccaat ggatggaaaa aatcgaacca
    16741 gaaaatgatg aatggctttc gccatctggt cgcgtcatcg acagtcaatt atcggaacac
    16801 caagatgaag ggttcttaga agggtacgtt ctgactggac ggcatggttt ttttgcaagt
    16861 tacgaatcat tcttgcgagt ggttgactct atgttgactc agcacttcaa atggatacgg
    16921 aaatcacatg acctttcttg gcgaaaagat tatccttcgc tgaatctcat tgcaagctca
    16981 acagtcttcc agcaagatca caatggatat agccaccaag atccaggaat attgacacat
    17041 ttggcagaaa agaaggcgga gttcatccgt gaatatctgc ctgcggatgc aaatacattg
    17101 ctcgcagtca tggataaagc attccgctcg tcagaaaaaa tcaatttgat catctcttcc
    17161 aaacatccgc gtgctcaatt ttactcagca gaagaagcag ccgtcttagt gaatgaaggc
    17221 ttgaaaatca ttgattgggc ttcgacagca aaagaggagg aacctgaatt ggtcattgct
    17281 gctgcaggaa cggaatctaa cttagaagca ttagcagctg taactttgct gctggaagaa
    17341 ttcccaaaac taaaaattcg gttcatcaat gtcgtagatt tattgaaatt acgtcatcca
    17401 agtcaagatc cgcgtgggtt gagcgatgaa gaatttgatc aatattttac aaaagacaaa
    17461 ccgatcttat ttgctttcca cggttatgaa acattggtcc gcacgatttt ctttgatcgt
    17521 cataaccatc atttaatgat tcatggctac aaagaaaatg gagatatcac gacaccattt
    17581 gacatgcgtg tagtaaatga acttgatcgt tatcatttgg caaaagacgc agctttaaaa
    17641 atcaaaggaa gtcaagcaga agattttgcg gaaaaaatgg atcagaaatt acaagaacat
    17701 caaaactata ttcgtgaaaa tggtattgat ctgccagaag tattggattg gaaatggaaa
    17761 aatcttgacc aataaaatga taaaatcgat cccgcaaaac agaatttttt acattgtatt
    17821 atttgtcaaa ttaag
//
LOCUS       DAZKKZ010000059        17579 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.060, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000059 DAZKKZ010000000
VERSION     DAZKKZ010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17579)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17579)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17579
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.060"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            283..522
                     /locus_tag="ACG8LA_002175"
     CDS             283..522
                     /locus_tag="ACG8LA_002175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204458.1"
                     /translation="MKRILFISLSNLLLLTACGTSASKNIPSDTQISNSIDSTISTNE
                     KNSPVETSDIKVSTSAKNRVKKLSARLLYFKQTLN"
     gene            complement(884..1144)
                     /locus_tag="ACG8LA_002176"
     CDS             complement(884..1144)
                     /locus_tag="ACG8LA_002176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204459.1"
                     /translation="MNNETIILGKKYICQPIGLKQKVVGEVISKLENCVVICVDEYHD
                     VDRNEILEKCGKVVAKYTHVYELETTEYLYNYSNKYEHTLVS"
     gene            complement(1329..1826)
                     /locus_tag="ACG8LA_002177"
     CDS             complement(1329..1826)
                     /locus_tag="ACG8LA_002177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0033745 - L-methionine-(R)-S-oxide
                     reductase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HFQ0204460.1"
                     /translation="MWTEKQKKDAYEILLLQQQGLLEAEDNWLANLANSSALLNETLP
                     ETVFAGYYLFDGNELILGPFQGRVSCTRIKMGKGVCGESAEKQETLIVDDVKTHANYI
                     SCDSAAQSEIVVPMVKEGNLIGVLDIDCGVTKGYDEIDQAFLEKYVDLLLANFNINAF
                     SFINN"
     gene            complement(1956..2666)
                     /gene="budA"
                     /locus_tag="ACG8LA_002178"
     CDS             complement(1956..2666)
                     /gene="budA"
                     /locus_tag="ACG8LA_002178"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047605 - acetolactate decarboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0045151 - acetoin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HFQ0204461.1"
                     /translation="MTEKILYQHGTLGALMAGLMDGTETIAHILEKGTLGLGTLHGLD
                     GEVIFLDGVAYQGRSDGSVAQLDGSELTPYAAITDFTPDTSFSVSKTADGEQLKKDIL
                     VREAGENLFLAVKITGLFKNMHIRIMPKQEKPYRRLAKISESQPEFQQSNVQGTLVGF
                     FTPELFQGVAAAGFHLHFIDDTHTFGGHVMDFEVAEGKVEISRISSLVQHFPVDDPTF
                     VHETIDYADLAAEIQQAE"
     gene            complement(2679..4343)
                     /gene="alsS"
                     /locus_tag="ACG8LA_002179"
     CDS             complement(2679..4343)
                     /gene="alsS"
                     /locus_tag="ACG8LA_002179"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0003984 - acetolactate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA];
                     GO_process: GO:0034077 - butanediol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase AlsS"
                     /protein_id="HFQ0204462.1"
                     /translation="MDEKMKQGSKSVVESLINHHVDYVFGIPGAKIDGVFNELEDQGP
                     ELIVTRHEQNAAFMAQAIGRITGEPGVVIATSGPGASNLATGLVTATAEGDPVLAIAG
                     QVKRSDLLKLTHQSMDNAALFQPITKYSAEIQDPETISEVIANAYRMAKSSKKGASFI
                     SIPQDVVDAPVQGNVIKPLSDPKLGSASADDIRYLAERIREAKLPVLLVGMRGSSEKE
                     TLAIRQLVGKTALPVVETFQAAGVISRELEAHFFGRVGLFRNQPGDMLLKRSDLVIAI
                     GYDPIEYEARNWNAEKDARIIVIDEAPAEIDPFMQPERELIGDISATLDLLTGSLEPQ
                     QVSEDAKEYLASLQAELTERDIVQSKGEAGILHPLEVINTLQSKVTDDMTVTVDVGSH
                     YIWMARHFRSYEPRHLLFSNGMQTLGVALPWAISAALVRPNTQIVSVSGDGGFLFSAQ
                     DLETAVRKKLNIVHLIWNDGHYNMVEFQEKMKYQRASGVDFGPVDFVKYAEAFGAKGI
                     RATSVEELEKALEEGFATEGPVIIDIPIDYRDNEKLGETILPDQFY"
     gene            complement(4548..5210)
                     /locus_tag="ACG8LA_002180"
     CDS             complement(4548..5210)
                     /locus_tag="ACG8LA_002180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HFQ0204463.1"
                     /translation="MKEQRFDKNVYMEFFYWLYQSLASSLCFWCVNILYIAAAFLLSI
                     DGRNVFSFIFSLLFIGPGCIVMIGMTEELAKEKSFSPVRLFIKTFRQFWLKGFFYWLF
                     AWIVSVIMIFDCFFFIRFSYGKWLIPLFVLLACLSVSFSINYWYFQVRNPASKPNQVL
                     RIAFYYTLKKWYVSLLDFLLLTSLFLFFFVKPQWCILLGPSIVFGLIYFNNRKLMRTM
                     DL"
     gene            complement(5220..6035)
                     /locus_tag="ACG8LA_002181"
     CDS             complement(5220..6035)
                     /locus_tag="ACG8LA_002181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFQ0204464.1"
                     /translation="MPFIQWLGMILLIVLALLTIIPFLWMVSASFKANNEVFTIPIQW
                     IPKTWHLENYLVIWSRIPLVTFFKNTAFLSVVITLIQLFTSSFAAYGFSKLNFKGRDI
                     LFLAYIGTIAVPWQSYMIPQFIMMRKVGLTYTLWSLVLLQAFNAFGVFLLKQYYSSIP
                     DSLCESARIDGLSEWGIYRKIILPLTKPAIASLTIITFVNTWNDYMGPFIYLSSTENK
                     TIQLGLKMFIGLFDAEYALIMAASVVSVLPVAFIFLAMQKYFVEGIASSGMKE"
     gene            complement(6297..6740)
                     /locus_tag="ACG8LA_002182"
     CDS             complement(6297..6740)
                     /locus_tag="ACG8LA_002182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator
                     substrate-binding protein"
                     /protein_id="HFQ0204465.1"
                     /translation="MLDPVDTEKYETILLPRKEKWGLLILENSVLAKKDVITKEDFAN
                     VPLLISKRPEIQRMFADWLGIKKEQLLITGTYNLIFNVFALIENQVGAALVIEGAVSH
                     LSKRVTFVPLDPMIETNCMLVWKKNRILSPVVNELIHRFKEAFEQ"
     gene            complement(6874..7212)
                     /locus_tag="ACG8LA_002183"
     CDS             complement(6874..7212)
                     /locus_tag="ACG8LA_002183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFQ0204466.1"
                     /translation="MYQVKKSRSIAMELRLLKYFWTIAEEGTISQAAEVLHLTQPTLS
                     RQLKELEEELGTELFVRENRKMILTEAGYFLKKPSRRNFRFNESNHSRIREQKKTIIQ
                     RPIYDRLCGS"
     gene            complement(7200..7577)
                     /locus_tag="ACG8LA_002184"
     CDS             complement(7200..7577)
                     /locus_tag="ACG8LA_002184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HFQ0204467.1"
                     /translation="MNIKQVSEEKGISADTLRYYERIGLIPPVNRTKGGIRDYTEEDL
                     KWVDFTICMRNAGLSIESLIEYIRLSSEGEATVFERRKLLIEESELLTKKIAEMQECL
                     ERLQGKIKKYDRVLSRNKMECIK"
     gene            7801..8994
                     /locus_tag="ACG8LA_002185"
     CDS             7801..8994
                     /locus_tag="ACG8LA_002185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFQ0204468.1"
                     /translation="MTTYQRKLLLSTSAGIALENMDIMFLAFSLSSMITSFHISGTQA
                     GFISTITNLGMLIGGIFFGIIADKYGRVKVFSQTVLLFSIASLLMYFASNIYLVYLFR
                     FIAGVGAGGEYGACMSLISESFSKKQIGRASSVAGIGAQVGAALAAILAAVIIPTFGW
                     KMLYVVGVLPVLMVLFIRRGLTEPKEFKSVQSAEKKTKLSRLFESKHLAWQTCGLSIM
                     VTVQIAGYFGLMNWLPSIMQNRLGLSVSGSSLWMVSTILGMSLGMMTFGIIMDKLGPK
                     LAFSLFLICSSLSVYLLVLAHSQWSLVAAAVIVGYFINGMYGGYGAVISSLYPTEIRA
                     TANNFIMNLGRAVGGFSSIVIGFLMDHYSLTAVILFLSGIYLVSLLVLTTLTGVTALR
                     ESLQH"
     gene            complement(9160..9582)
                     /locus_tag="ACG8LA_002186"
     CDS             complement(9160..9582)
                     /locus_tag="ACG8LA_002186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0204469.1"
                     /translation="MQTFLTKVSQKKIKMIHLLLETERWCSIEELQNELKVSSKSILN
                     YLTDLEELFQKYPDKVILKNENNRRFSMEKQENFPIYIIYLHFYRKSYNYHLIEFMYQ
                     HPEKNLEDYADAQYTSVSTVFRYAKLLVKYFEMTDVKE"
     gene            9953..10627
                     /locus_tag="ACG8LA_002187"
     CDS             9953..10627
                     /locus_tag="ACG8LA_002187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204470.1"
                     /translation="MKKLVALFLVAGSLLSGCGATTSTTQSTSSAQASSSSTTISEST
                     ADSSKEQEQIEKKKEEEKQKAEKAALEKKVTEAESALSQAEANPTKENYATASAAIQA
                     LPENKQELTSRLAAIDSTIKAKEAEEERKKQEEIARQQAEQAQQEAIAQQQAEQARQQ
                     AAAEQASQQAQAAAPEQNNEQTVYVTPTGSKYHTHKCGNGTYTPATLSEAQARGLTPC
                     SKCYGN"
     gene            complement(10789..11961)
                     /locus_tag="ACG8LA_002188"
     CDS             complement(10789..11961)
                     /locus_tag="ACG8LA_002188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HFQ0204471.1"
                     /translation="MNKSRIRILDIFMAIILVVGIGIFSYPFVEDSLNDFLAQQMIIH
                     YQKQASNKNSEEIKKQQEKMTKKNQQLAEQNVSPGIGSFNQAVDAKALKDLPSNAFFM
                     EHMLGVIEIPKINVSLPIFDQTTEIFLQKGTSLLEESSYPTGGKNTHAVLSGHRGLPE
                     AKLFTDLPKLKKGDQFFIQINGKTLAYQVEKIQVVLPDEVDSLGIQKGRDLVTLLTCT
                     PYMVNTHRLLVTGHRIPYQAKEAKKAIQGIDQWKKWKFFIWFIGILLGSIGLVWLLIA
                     YLDSLAIAKRNYPLSFYVKNTNGRPIEGMVFSVKTLNGKHYITREKVPFVKASDEYGL
                     VRFSDLKGRNYRLQHEELLLKIHVKHKHSKQFSMKLKKGRYKLRKEKEVYYLIEKE"
     gene            complement(12167..13456)
                     /locus_tag="ACG8LA_002189"
     CDS             complement(12167..13456)
                     /locus_tag="ACG8LA_002189"
                     /inference="COORDINATES: protein motif:HMM:NF033902.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HFQ0204472.1"
                     /translation="MKFTSAPENQINNGTELTFPNSEPLNGVEFNVYDITATYYPSKD
                     TAVPADATPFASVTTSGEGLANLTLPGKSDGKDAVYVFVETPKPGVETSPNIVLSLPF
                     YNPNSSDPDKPLDTIHLYAKNVIKESNIKIQKAGNFSGVDKLAGAQFQIKNSENQFVT
                     GFDENTGVALYDPAESALTFTTDTEGSISVNGLIDGNYTLVETKAPDGYQLTNPQKET
                     TFIVKNGKLQQTTGIIHGADEANLGNPNGVVNRENTTTDNTITVENVQNYGDFHFIKQ
                     DVNTQEKLADAEFSILRAKDPTVKLMKKIANLASGEYPYAWSDEVTGSDWEEVKLISD
                     SEGKFSIEGLKQGAYCLQETKAPEGYALPKNEAAYTEFTVDDDPTTSDETTIDNQPKG
                     ILPSTGGMGIIVFILVGTALVGGAVIYFKKRHQETEA"
     gene            complement(13593..14108)
                     /locus_tag="ACG8LA_002190"
     CDS             complement(13593..14108)
                     /locus_tag="ACG8LA_002190"
                     /inference="COORDINATES: protein motif:HMM:NF037639.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prealbumin-like fold domain-containing protein"
                     /protein_id="HFQ0204473.1"
                     /translation="MDRQTKQKLADAQFLVKKNDQYLAQENGINHWVAKDDSRATIFT
                     SSKDGTFSVHGLSFGSYELVEIKPPKGYILSQSTILFEVEKGSYDPLHPIPLEIINEP
                     KANPTNNGKTPVQMQTNGPSNEKNGGSFPKTSEEMLGGFSILGLLLVLSTGTAWFYKK
                     QQKGNNRREIK"
     gene            complement(14181..15095)
                     /locus_tag="ACG8LA_002191"
                     /pseudo
     CDS             complement(14181..15095)
                     /locus_tag="ACG8LA_002191"
                     /inference="COORDINATES: protein motif:HMM:NF027869.4"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pilin N-terminal domain-containing protein"
     gene            complement(15092..17419)
                     /locus_tag="ACG8LA_002192"
     CDS             complement(15092..17419)
                     /locus_tag="ACG8LA_002192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBG domain-containing protein"
                     /protein_id="HFQ0204474.1"
                     /translation="MKMIKKTQNKIQRICQKHFVSRLKAVSKRKYLHPIMISIILIFT
                     FLGSLSSIYVNVYTETSNFANQTTEETNSPPYSEIQSIESTNQSSNNETTSTTSSTQL
                     IDPTEKEITAAKAAGEKAYSETGRSQTFSTVAATANFNGHTIPDGYTVIYAKDGVIVA
                     VNGSMSADKTALQGVTKAIAFIDNRPDIHNLFIGSTVNGTTITFPKSIYMGVATAGNT
                     IDSVTPNADKSYSFTPSTWGGLPAGGGMSTFSIGIQLANDIPFTGYSIKNGQIVDGKG
                     NVSNFPTYQAATVQVNANRTGTFSYTVNGGAAKIGTYGTTLSGIHVGDKVVITPTAVT
                     GYSFAQTNGSFTALESNVDTVTYTGKQTPITIKYQDYFGQMIAPSKIMNLTYGSAAQD
                     LTTNTPTINGYTFTAVSATETKNQSAMSVLASLDTNGNVIVKDANGKQISEVILYYKT
                     NATVSINANGSKYYDGLSVVPIVKYAFNDKTESTSLLNNDLSIDQITWNPTDFKAMNE
                     KGVEVTAPTEIGTYTSWQLTKSGLAKLAARTNYLFTIVQTSDVYTIKQISGAVELSGS
                     KTYDGKAGVPSIHVKLAEGVTSSLTPVQVALSSMDYTADAQSAKNMVNAGSYTIKLTN
                     SGIDKVKAANPKLSFTDIANTSGTYTIYKANAVITVDDAAFNYDAQSHSISVGNLHVT
                     GVVLGESLDYTLTVNSRTDIGSQIVTISLGEGSVNNNYTIIATDTAKLTINPTLLLPS
                     TGGIGLLPFVFLGLIFIFSGFFYFIHRKKKAGEQR"
BASE COUNT         5071 a         3480 c         3051 g         5977 t
ORIGIN      
        1 ctatcctcct agcaactatt taaataccca aaaaaattac ctctagataa tatcatacct
       61 acgttttcac ttataaattt tttcataaaa aaagcgttta gaggcataat cgttaataca
      121 gatggtaacc aatgtatctg gtttgaactg ggatatcacc ctctccatat atgtattact
      181 aagactaata gatactataa aagacttgat agttttgcat tgattttgcc taatactgag
      241 cataggtgta tgctaaacga tactataagg agtgtgtaca taatgaaaag aattctgttt
      301 atcagtttat caaatttatt gttacttact gcttgtggga cttctgcatc aaagaacata
      361 ccttcagata cgcaaatttc gaatagtatc gattcaacaa tttctacaaa tgagaaaaat
      421 tctccggtag aaacttccga tataaaagtt tctacctctg caaaaaacag ggtaaagaaa
      481 ctgtcagcac gtctccttta tttcaaacaa actctgaatt agcttcttca tcttcttcag
      541 caaataatga tgatagtttc gcgtttactc ctaactaaat gcaaccttta caaatgcttt
      601 acgataacaa gcctgagcta aatgatcctg atatcagttt tgcatttttt gaaatgattg
      661 gatcggatga tctttttaaa actactagtt tgtctatccg aaaataggac agttctggca
      721 gtataggttt ttatcgagtt tctccaccag gcctcgttac agagacagat tctctaggcg
      781 aaccttttga ataaatcaaa aatcatgaac aatcactgcc aactaaataa agtgccttca
      841 aaagcttggt cttctcgctt ttgaaggcac tttatttaaa tctttatgaa actaaagtat
      901 gttcatattt gttgctatag ttatatagat attctgttgt ttccaactca taaacgtgag
      961 tatattttgc cactactttt ccgcattttt ctaatatttc attgcgatcg acgtcatgat
     1021 attcgtctac gcagatcaca acacaatttt ctaatttact gattacttct ccaaccactt
     1081 tttgtttcaa gccaataggt tggcaaatat atttttttcc taaaatgata gtttcgttat
     1141 tcatatttca tccatcctta atgtttttcc attatttaaa atgataatac cattaaaata
     1201 tgattatgaa aatcaataac acttgtgatt ttataaaaaa ataaaaaaac cgaaaaacag
     1261 aaatgcccac tgtctttccg gctcttttta ttcttgattt ctcttctttt ttgtttcaat
     1321 agacgatttt agttattaat aaatgaaaaa gcatttatat taaaatttgc taataaaaga
     1381 tctacatatt tttctagaaa tgcttgatcg atttcatcat accctttcgt tactccgcaa
     1441 tcgatatcta aaacaccgat taaattacct tcttttacca ttggcactac gatttctgat
     1501 tgtgcggctg aatcgcagga aatgtaattt gcatgggttt tgacatcatc aacgatcaat
     1561 gtttcttgtt tttcagctga ttctccacaa actccttttc ccatcttgat acgtgtgcaa
     1621 gaaactcgcc cttggaacgg tcctaaaatc aattcattac catcgaataa ataatatcct
     1681 gcaaagacag tctcaggcaa agtctcattc aacaatgcag atgaatttgc taaatttgct
     1741 aaccagttat cttctgcttc taataatcct tgttgctgta ataataaaat ttcgtatgca
     1801 tcttttttct gtttttctgt ccacatgata aaaaccgctc ctttttgatc tatggagaag
     1861 attatagctc agtttttttg taaacgctag gtttcctcct caaaaaaacg agatacgtca
     1921 ggttaatcac cttgaacgca tctcgctgtc tttttctatt ctgcttgttg gatttctgct
     1981 gctaaatcag cataatcaat cgtttcgtga acaaaagtcg gatcatcaac tggaaaatgc
     2041 tgtacaaggg acgagatgcg gctaatctca acttttcctt cagccacttc aaaatccatt
     2101 acatgtccgc caaatgtatg tgtatcatcg ataaaatgca agtgaaatcc cgctgcagca
     2161 actccttgga ataattcagg cgtaaagaac ccgactaatg ttccttggac attgctttgt
     2221 tggaattctg gttgagactc tgaaattttt gctagtcttc tgtaaggttt ttcttgcttc
     2281 ggcatgatac ggatgtgcat atttttgaat aatccagtta tcttcactgc caaaaatagg
     2341 ttttccccgg cttctcttac taatatgtct tttttcaatt gttctccatc tgcagttttt
     2401 gagacagaaa aactagtatc tggcgtaaaa tctgtaattg ctgcataggg ggtaagttca
     2461 cttccatcta attgggcaac tgagccatct gatcttcctt gataagctac gccatctaaa
     2521 aagatgactt caccatcaag cccatgcaat gttcccaatc ccagagttcc tttttctaat
     2581 atatgagcaa tcgtttctgt tccatccatc aagccagcca tcaaagctcc taatgtcccg
     2641 tgctggtata agattttttc agtcatgtcg acacttcctt aatagaattg atctggtaag
     2701 attgtttctc ccaatttctc attatcacgg taatcaatcg gaatatcaat aattacgggt
     2761 ccttctgtcg caaatccttc ttctaaagct ttttctaatt cctctacact tgtagctcgg
     2821 attcctttag cgccaaaagc ttctgcatat ttcacaaaat caactggacc aaagtctaca
     2881 cctgacgccc gctgatattt cattttttct tggaactcta ccatattgta gtgtccatca
     2941 ttccaaatca aatgaacgat attcaatttt ttacgtaccg ccgtttctaa atcctgggca
     3001 gagaataaaa atcccccatc gccggaaact gatacgattt gtgtatttgg acgcaccaat
     3061 gcagcagaaa tcgcccatgg caatgcaaca ccaagcgttt gcataccatt actgaataac
     3121 aaatgacgag gttcataact tctaaagtgg cgtgccatcc aaatataatg actacctaca
     3181 tctacggtaa cagtcatatc atctgttact tttgactgaa gcgtgttaat aacttctaaa
     3241 ggatgcaaga tacctgcttc tccttttgat tgaacaatgt cccgctccgt taattctgct
     3301 tgaagagatg ctaaatattc ttttgcatct tctgacactt gttgaggctc taatgaacct
     3361 gtcaataaat caagagtggc tgagatatca ccgatcaatt ctctttcagg ctgcataaaa
     3421 ggatcgattt cagctggcgc ttcatcgatc acaatgatcc gcgcatcttt ttccgcattc
     3481 cagtttcttg cttcatattc gattggatca tagccaatag caataactag atcacttcgt
     3541 ttcaaaagca tatctcctgg ttggtttcta aataaaccca cacgaccaaa gaaatgcgct
     3601 tctaattcac gtgagatcac tccagctgct tggaatgtct ctacaacagg caatgctgtc
     3661 tttccaacta attgcctgat ggctaacgtt tctttttcac ttgatcctcg catacctact
     3721 aatagtaccg gtagttttgc ttctctaatg cgttcagcta ggtaacggat atcatctgca
     3781 gaagcagaac ctaatttagg atcgctcaat ggcttgatga cattcccttg gacaggtgca
     3841 tccactacat cttgcgggat actgataaag ctcgcgcctt tttttgaact cttagccata
     3901 cgataagcat tggcaatcac ttctgaaatt gtttctggat cttggatttc tgcactgtat
     3961 tttgtgattg gctggaacag tgctgcatta tccatgcttt gatgggtcaa cttcaataga
     4021 tcgcttcgtt ttacttgtcc ggcaattgct aaaactgggt caccttctgc tgtcgctgtt
     4081 accaaacctg tagctaagtt actagcacca ggaccacttg ttgcgataac tactcctggc
     4141 tctcctgtaa tacgtccgat tgcttgtgcc ataaatgcag cattttgttc gtgacgagtc
     4201 acgattaatt caggaccttg atcctctaat tcattaaata caccatcgat ttttgcacct
     4261 ggtataccga atacataatc aacatgatga ttaatcaaac tttctactac agatttcgaa
     4321 ccttgtttca ttttttcgtc cattgaacat cgtccttttt atgctttatt tttaattatt
     4381 agttagaaat aatcacaaat aattgataca gtttctaaac ctgtttcatt caaaagtata
     4441 gcacgtttta tttcatttgt ttagccatat gtttcaaaaa atgaaaaaga atgacagttt
     4501 ttacataaaa actgtcattc ttaattgaaa gtttcaattt ataaagtcta cagatccata
     4561 gttctcatca atttacgatt gttgaagtaa atcaaaccaa atacgataga aggacctagt
     4621 agaatacacc attggggctt tacgaaaaag aagagaaaca aacttgtcaa tagtaaaaaa
     4681 tctagtaaac tcacatacca ttttttcaac gtatagtaga acgctatccg tagaacttga
     4741 tttggtttcg acgctggatt tctcacctga aaataccagt agttgatgct aaaggaaact
     4801 gataaacaag caagtaaaac aaacaacgga atcaaccatt ttccataaga aaaacgtata
     4861 aaaaagaaac aatcaaaaat cattatcaca ctaactatcc aagcaaatag ccaataaaaa
     4921 aatcccttta gccaaaattg gcgaaacgtc tttatgaaca aacgtactgg tgaaaaactt
     4981 ttttcttttg ctaattcttc tgtcatacct atcatcacga tgcaacctgg accaataaaa
     5041 agtaaagaaa aaataaagga aaagacattc cttccatcta tcgacaaaag gaacgcagct
     5101 gctatataca agatattgac acaccaaaaa caaaggctac ttgccaatga ttgatacaac
     5161 caataaaaga attccatata aacatttttg tcaaaacgct gctctttcat aatcacctcc
     5221 tattccttca ttcctgatga agcgatccct tctacaaaat atttttgcat cgctaaaaat
     5281 ataaaagcaa caggaagaac agaaacaact gaggcagcca tgattaatgc gtactctgca
     5341 tcaaatagcc caataaacat tttcaaccct aactggattg ttttattttc cgtagaagac
     5401 aaataaatga atggccccat ataatcgttc catgtattaa cgaatgtgat gatcgtcaaa
     5461 ctggcaatcg ccggttttgt aagaggtaaa atgatcttgc gatagattcc ccactctgat
     5521 aagccatcga tccgcgcact ctcacataaa gaatctggga tactactgta gtattgcttc
     5581 aacaagaaca caccaaaagc attgaacgct tgtaatagca ccaacgacca caacgtatat
     5641 gttaaaccca cttttctcat cataatgaac tgcgggatca tataagactg ccaagggaca
     5701 gcaatcgtgc cgatatatgc taaaaataaa atatcgcgcc ctttaaaatt tagtttagaa
     5761 aacccgtaag cagcaaaact agaagtaaac aactgaatca acgtgatcac aacgcttaaa
     5821 aaagctgtat tcttaaaaaa tgtcactaaa ggaatacgag accaaataac cagataattc
     5881 tctaaatgcc aagttttagg gatccattga atcggaatcg tgaacacttc attatttgct
     5941 ttgaatgaag cagaaaccat ccataaaaaa ggaatgatcg tcaataaagc taatacaatc
     6001 agcagaatca tacccaacca ttgaataaag ggcatgtttt ttgaacgaat ttttgctttt
     6061 tttctttcat ttcgaacacc tccaaagtta taatcttcat ttgtttgtaa tgattacaat
     6121 ccagaacaac ggttattata gctgattcat ttccgttctt cttatgtttg taagcgctta
     6181 tttaacaagt tatgtaaatc tctttatttt ttttgattta aaaatgaaaa aatacaaaag
     6241 caagactgtc atacgtctcg cttttgtatt gaaatttctt cgattagaga tacttattac
     6301 tgttcaaaag cttctttgaa acggtgaatc aattcattga ctacaggtga taaaatccga
     6361 ttctttttcc agactagcat gcagttcgtt tcaatcattg ggtcaagcgg aacgaatgtc
     6421 actcgctttg aaagatgact tacagcacct tctatgacta aagcagcacc tacctgattc
     6481 tcaattagcg caaatacatt gaaaatcaaa ttgtacgttc ctgtgatcag caactgctcc
     6541 ttttttatgc ctaaccagtc agcaaacatt cgctgtattt ctggacgctt tgagatcaaa
     6601 agaggtacat tcgcaaagtc ttcttttgtt atcacgtctt tttttgctaa aacagaattt
     6661 tctaaaatga gcaatcccca tttttccttt cttggtaaca aaatcgtttc gtatttctct
     6721 gtatctactg gatctagcaa aatcgctaaa tctaacaggc ttttttctag tcactccgtg
     6781 atatcatcac ttgttccgct gtggatatga aattgaacgc tgggataatc acggatcaac
     6841 ttttctagta atagtgccaa tgtattcgaa ttatcagctt ccacacagcc gatcgtaaat
     6901 cggccgctga ataattgttt ttttctgttc tcgaattctt gagtggtttg attcgttaaa
     6961 tctaaaattt cttctgctcg gcttttttag aaaataacct gcttctgtca agatcatttt
     7021 gcggttttcg cgtacaaaca gttctgttcc tagttcctct tctaactcct tcagttgtcg
     7081 gcttaaggtt ggttgtgtaa gatgtagaac ttctgcggct tgagagattg ttccttcttc
     7141 tgcaattgtc caaaaatatt ttagtaagcg taactccata gcgatgctcc ttgatttttt
     7201 tacttgatac attccatttt atttctagat aacacacgat catatttctt gatttttcct
     7261 tgtaaacgtt ccaaacattc ttgcatttca gcaatttttt tcgtcaaaag ttcactttct
     7321 tcaatcaaaa gcttacgccg ctcaaataca gttgcttctc cttcgctaga taggcgaata
     7381 tattcaatca aagactcgat cgataatccg gcatttcgca tacagatcgt aaagtcgacc
     7441 cattttaggt cttcttctgt ataatcacgg attccgcctt ttgtccgatt aactggtgga
     7501 atcaacccga ttcgttcata atagcgcaat gtatcggccg aaatgccctt ttcttcactg
     7561 acttgtttga tattcatctg atcactcttt ctcttaattt cttgccactt tacttatgta
     7621 ttttatttat tctacaactt taagtgtact ccaagtcaat actcatttct attaaaacta
     7681 agctggatta tctatatcgg ttgtttgtgt attatttcaa ataaaaaagt cttgtttttt
     7741 tattcttttt tggatatact tttaacaatt tagggaaatt ttaggaaaag gggtataaaa
     7801 atgacaacgt atcagcgaaa gttattatta tcgacatcgg cgggaattgc tttagagaat
     7861 atggatatta tgtttttagc tttttcatta tcttcaatga ttacttcttt tcatattagt
     7921 ggtacgcaag cgggtttcat ttcaacgatc actaatttgg ggatgctcat tggaggtatt
     7981 ttttttggca tcatagctga taaatatgga cgtgtgaaag tattttctca aacggtcctt
     8041 ctgttttcga ttgcttcttt attgatgtat tttgcttcaa acatctactt ggtttatctc
     8101 tttcgcttta tcgcaggtgt aggagcggga ggagaatacg gggcgtgtat gtccttgatt
     8161 tccgaaagtt tttcaaaaaa acaaattgga cgagcttctt cggttgctgg tattggtgcg
     8221 caggtcggtg cggctttggc tgcgatttta gctgctgtga tcattccaac gtttggttgg
     8281 aagatgttgt atgtcgtagg tgtactgccg gtgttgatgg tcttgttcat tcgtcgcggc
     8341 ttgactgaac caaaggaatt caaatctgta caatctgccg aaaagaaaac caaacttagc
     8401 agactgtttg aatcaaaaca tcttgcttgg caaacatgtg gccttagtat catggtaact
     8461 gtccaaattg ccggctattt tgggttaatg aattggctgc cttcaattat gcaaaatcga
     8521 ttagggcttt cggtttctgg gtcttcattg tggatggtca gtactatttt aggcatgtct
     8581 ttggggatga tgacttttgg cataatcatg gataaattgg ggcctaaact agccttttct
     8641 ttgtttttaa tttgttcatc cttatctgtc tatctacttg tgttagccca tagccagtgg
     8701 agtttggtag cagccgctgt gatagtcggc tactttatca atggcatgta tggtggatat
     8761 ggcgcagtga ttagtagttt gtatccaaca gaaatccgcg cgacggcgaa taatttcatt
     8821 atgaaccttg gacgagctgt tggtggtttt tcttctatcg tcatcggttt cttgatggat
     8881 cattatagtt taactgccgt aatcttgttt ttgagcggta tttacctagt cagtctgctg
     8941 gtcttgacaa ctcttactgg tgttacagca ttaagggaaa gcttgcagca ttgatagttg
     9001 agtctgtaaa tgacaagaaa gaggtgtggc aaaagcttgc atctgcggta ataagaccag
     9061 ccaaatcaaa aacatgagac actgtttccg tttggctggt cgtattactt gatgcagggc
     9121 agctttttca actgctaatt tccttctatc tggcggctac tattctttga cgtccgtcat
     9181 ttcaaagtac tttactaata acttagcata acgaaaaact gtggatacac tcgtatattg
     9241 agcgtctgca taatcttcca aatttttctc aggatgttga tacatgaatt caatcaaatg
     9301 ataattatat gattttctgt agaaatgaag ataaataatg tagattggga agttctcctg
     9361 cttttccata gaaaagcgcc gattattctc attcttcaaa atgaccttat caggatattt
     9421 ttggaacaat tcttctaaat ctgttagata attcaagata gacttacttg ataccttcaa
     9481 ttcgttttgt agttcttcta ttgaacacca acgttctgtt tcaagcagta aatgaatcat
     9541 tttaattttc ttttgagaaa cttttgttaa aaaagtctgc atattttctc ctcctgtatc
     9601 tactttacta tactacatac aagaaaaaaa acggatacaa atatcatatt gtcacaccgt
     9661 caatagtgca taaacctgtt attatttctc tttttttcct aagtattcta ttgatatgaa
     9721 tcatttaatc gtttattata taaatgtcaa taatctaata ataaaataac gtacatattt
     9781 tattattgca tacttaataa cagaactata gcaaaaaatc ccgtgtatca aaacgggatt
     9841 agattaagtt tcctcaatca ctattcataa cacaattatt ataacaagta agtaaacaat
     9901 tgaaaaggac atttattgaa aacggttgtt ttttacttaa ggaggaaatt tagtgaaaaa
     9961 attagttgca ttgtttttgg tcgcaggaag tttgttgagt gggtgtggtg ctactacgtc
    10021 tactactcaa agcacaagtt cagctcaggc ttccagcagc agtaccacga tctccgaaag
    10081 tacggcagat tcatcgaaag aacaagaaca aattgaaaag aaaaaagaag aagagaaaca
    10141 aaaagcggaa aaagctgcac tagaaaaaaa agtgacagaa gcggaatctg ctttgtcaca
    10201 agctgaagca aatcctacaa aagaaaacta tgcaactgct tcagcagcta tccaagcgct
    10261 acctgaaaac aaacaagagt tgacaagccg tcttgctgca attgattcca caatcaaagc
    10321 aaaagaagca gaagaagaac ggaaaaagca agaagaaatt gcacgacaac aagcagaaca
    10381 agcgcaacaa gaagcaatcg cacagcaaca agcagaacag gcgcgacagc aagcagcagc
    10441 tgaacaggcc tctcagcagg cacaagccgc agctcctgag caaaataatg aacaaactgt
    10501 ctatgtcaca ccgaccggtt caaaatacca tacacataaa tgtggaaatg gtacgtatac
    10561 ccctgccact ttaagcgaag ctcaagctcg tggtttaacc ccttgctcca aatgttatgg
    10621 aaactaattc aaaagttata ctataataat aaaattcttc tgaaacataa aaaaatagaa
    10681 gctggcgttc cagatagtaa accaaaaata gcagtttaca cgtccatttc gtcagcttct
    10741 ctcttttttc atttagtctg ttccctctgc ttttttggac atcttcattc attctttctc
    10801 aatcaaatag tacacctctt tttcttttcg cagtttatat cttccttttt tcaatttcat
    10861 tgaaaactgt ttcgaatgtt tatgttttac atggatttta agcaggagct cctcatgttg
    10921 caagcgatag ttcctgcctt ttaaatcaga aaatctcact agtccgtatt catcagaagc
    10981 tttcacaaat ggaacttttt ctctagtaat atagtgtttg ccgttgagcg tttttacaga
    11041 aaagaccatt ccttcgattg gtcgtccgtt tgtgttcttt acataaaaag ataaaggata
    11101 gtttcgctta gcgatggcca aagaatctaa ataagcgatg agtagccaaa ctaagccgat
    11161 tgatccaagt agtataccga taaaccaaat aaaaaatttc cattttttcc attgatcaat
    11221 tccttggatc gctttttttg cctcttttgc ttgataagga atacgatgcc ccgtcacaag
    11281 cagtcgatgt gtattgacca tataaggagt acaggtaagc aaagtcacga gatctctgcc
    11341 tttttggata cccaaagaat ctacttcatc aggtaagacc acttggattt tttctacttg
    11401 atacgccaat gtctttccat tgatctggat gaaaaactgg tctccttttt tcaacttagg
    11461 caaatctgta aataattttg cttctgggag tccacgatgc ccagaaagaa cggcatgggt
    11521 gtttttcccg ccagtcggat aagaactttc ttccaataat gacgttcctt tttgcaaaaa
    11581 tatttccgtt gtctgatcga atataggtaa gctgacattg atttttggga tttcgatgac
    11641 tccaagcata tgttccataa aaaaggcatt actaggtaaa tcttttaatg cttttgcatc
    11701 aactgcttgg ttgaaactgc ctatccctgg tgatacgttt tgctctgcca actgttggtt
    11761 tttctttgtc attttttcct gctgtttttt tatttcctct gaattcttat tcgatgcttg
    11821 cttttgataa tggatgatca tttgctgggc aagaaaatca ttcagtgaat cttctacaaa
    11881 aggataagaa aagatcccga tcccaacgac taaaatgatt gccatgaaga tgtccagtat
    11941 tcttattctg cttttattca tcatgtccac ctattttcta atatgtatat gaagaggttg
    12001 tgaaatcagc gccttgacct gagtattcgc tcaacaaacg gcaaaatagt tcctcctatt
    12061 ttgccgtttg ttgagcgaat accaagagac cgaccacttg tcacaacctt tctccccatt
    12121 tgaatcacta tcgtttattt atcgtatgat ttttgtttcc aatagtttaa gcttctgttt
    12181 cttgatggcg ttttttgaag tagatcactg ctcctccaac taaagcagta cctaccaaga
    12241 tgaatacgat gatccccata ccaccagttg aaggcaagat tcctttaggt tggttatcga
    12301 tcgttgtttc atcagaagtt gttggatcat catctactgt aaattcagtg tacgcagctt
    12361 cattcttagg taatgcgtag ccttctggtg cttttgtttc ttgaaggcag tatgcccctt
    12421 gtttcagccc ttcgattgaa aatttccctt ctgaatcaga aatcaatttc acttcttccc
    12481 agtcagaacc tgtgacttca tctgaccaag catatgggta ttctcctgag gcaagatttg
    12541 ctattttttt cattaattta acagttggat cttttgctct tagaatagaa aattctgcat
    12601 cggctaattt ttcttgcgtg ttcacatctt gtttgatgaa gtggaaatca ccgtagtttt
    12661 ggacattttc tacagtaatc gtgttatccg tagttgtatt ttcccgattg actacaccgt
    12721 ttggattccc aagattggct tcatctgcgc catggatgat accggttgtt tgttgcaatt
    12781 ttccgttttt tactataaaa gtagtttctt tttgtggatt ggttaattga taaccatctg
    12841 gtgcttttgt ttcaactaaa gtataattgc cgtctattaa tccattgaca ctgatggatc
    12901 cttcagtatc agttgtgaat gtcaacgctg actcagcagg atcatagaga gcgacaccag
    12961 tgttttcatc aaaaccggtc acgaattgat tctctgaatt tttgatctgg aattgcgccc
    13021 ctgctaactt atctacccct gaaaagttcc cagctttctg gattttgata ttgctttctt
    13081 tgatgacatt tttagcatat aggtgaatcg tgtctaaagg tttgtcaggg tctgatgaat
    13141 tcgggttata aaagggtaag cttaacacga tatttggcga cgtttcgaca ccgggctttg
    13201 gtgtttctac aaagacgtat acagcatctt tcccatcaga tttacctgga agagtcaggt
    13261 tagctaatcc ttcaccagaa gtcgttacac ttgcgaaggg tgtagcgtct gctggaactg
    13321 ctgtgtcttt acttggatag tacgtagcag tgatgtcata tacgttgaat tcaacgccgt
    13381 tcaacggttc gctattcgga aatgtcaatt ccgttccgtt gtttatttga ttttctggtg
    13441 ctgaagtgaa tttcaattta tgcaaattaa ccgtaacatt ttctggtgta ggtgatacgg
    13501 cctagaaacc tctgcagttc ctaggccgag aacgaaagga agcagcatga tagcagttcc
    13561 taaaaacgtc catatttttg ttttgatgtt tttcatttta tttccctcct attgtttcct
    13621 ttttgttgtt ttttataaaa ccaagctgtc cctgttgaaa ggactagcaa caaccctaaa
    13681 attgagaaac ctccaagcat ctcttcgctt gtttttggaa agcttcctcc atttttttca
    13741 tttgatggac catttgtctg catctgaact ggcgtttttc cattattcgt cggatttgct
    13801 tttggttcgt tgatgatttc caatggtata ggatgaagcg gatcataact gcctttttca
    13861 acttcaaaga gaatggttga ttgactcaat atatatcctt taggcggttt aatctccact
    13921 agttcgtaac ttccaaaaga caatccatgg acagaaaatg ttccatcttt actggaagta
    13981 aaaatcgttg ctcttgaatc atctttggct acccaatgat ttatcccgtt ttcttgcgct
    14041 aagtattggt catttttttt gactagaaat tgagcatctg ctagtttttg tttcgtttgc
    14101 cgatccactt tgacaaattg tttgcctcct gtttggatgg caagatgtgt ttctactgtt
    14161 tgattgtcag tcgtcaaacg tacatcgtta tcaaatgtcg ttttttcact gttttctttc
    14221 aatgtcattt ggtaacggat cgttaatttt ttcccagcaa acgaactaag atcttttcca
    14281 gaatctgata agacaaaacc atgttttgtt ttttgtgtgt gaaatgtatg aatcttgtct
    14341 ccaccaatca aaaaatcgat cgtttctggt tctagccata actgaggatc agctgtatct
    14401 ttgatcgtat aggttcctat ctcgttgatg ttctcaggaa ttgttacggt gatgagataa
    14461 ggaactttat ccccatctgc aaaatctgtc tgcttattct ctactgtttt tgttaatgtg
    14521 agtgcagcag gtattttttg ttcgctcttt ggatacaagt ggatggtcgt caatttatga
    14581 ttagatgaat ctgtcacagg aagcacaacg acaaatggtg ctgatttttc ttttacttaa
    14641 tctgaagtct ttatttccgc aaatcggtaa acagcgtcac gaccttgctc atctttgtcc
    14701 gatgcactaa aagaagcaat gccctcttcc tcgtctactg tttttgtcac attttctgcc
    14761 agtatttttt cactatcact tttttgtgct agttttcttt gtgcgtcttc cacactactt
    14821 ccttctgacc gcagcttgta aaattcatcc gagacatcat atatagcgaa agtaacgccg
    14881 ttcaaccctt ttactccttg aaagttatcc gggatattta ttccgtcgtt ttgactgata
    14941 cttggcatct tatcgctttc gaacattcga ttatgcaaag taaatgtaat aggtgattct
    15001 ctagctgaca cagtcggaga acctataaaa aagaccagta ggataaaaaa gagaacagca
    15061 aatatatcca cacgtacatt ttttgttttt ttcatcgctg ttcacctgct tttttcttac
    15121 gatggataaa ataaaagaag ccagaaaaaa taaagatcag tcctaaaaag acaaagggca
    15181 gtagacctat cccacctgtc gaaggaagca agagagtcgg attgatcgtc aacttagcgg
    15241 tatctgttgc gataatcgta taattattgt ttacacttcc ttcgcctaaa ctaatcgtta
    15301 ctatttgtga tccaatatct gtccggctgt taactgttag ggtataatcc aatgattcgc
    15361 ctaagacaac accggtaacg tggagatttc caaccgaaat cgagtgactt tgggcatcat
    15421 aattaaaggc agcgtcatcg acagtaatca ctgcgttagc tttatagatg gtataagttc
    15481 ctgatgtgtt ggctatatca gtaaatgaca acttgggatt tgctgctttg actttgtcta
    15541 ttccgctatt cgttagttta attgtatagc tgccagcatt aaccatattt tttgctgatt
    15601 gtgcatctgc tgtgtaatcc atactgctaa gtgccacttg tactggagta agcgaactag
    15661 tgacaccctc tgctagcttg acatggattg acgggacacc tgcttttcca tcatatgtct
    15721 tactgccact gagctctacc gcaccgctga tttgcttaat cgtatagaca tcagatgtct
    15781 gcacgatagt aaataaatag tttgttctgg cagctagttt agctagtccg ctttttgtca
    15841 attgccaaga cgtataggtt ccaatttcag taggcgcagt tacttcaact cccttttcat
    15901 tcatcgcttt gaaatcagtt ggattccatg tgatttgatc aatactgaga tcattgttta
    15961 aaagggatgt tgattctgtt ttatcattaa aggcatattt aacgatcggt acaacagaaa
    16021 gaccatcata gtacttactg ccatttgcat tgattgatac tgttgcattt gtcttataat
    16081 ataggatgac ttcagaaatc tgttttccat ttgcgtcctt tacgattaca tttccatttg
    16141 tatctaaact agctaaaaca ctcattgctg attggttctt tgtttctgtc gctgaaacag
    16201 ctgtaaaggt atatccgttg atagtaggcg tattagtcgt caggtcttgt gcagcacttc
    16261 cgtaagtaag attcattatt ttagaaggag caatcatctg tccaaaatag tcttgatact
    16321 taatagtgat tggtgtttgt ttgcctgtat aggtcaccgt atcgacgtta ctttctaggg
    16381 ctgtgaaaga accgtttgtt tgtgcaaaag aatagcccgt tactgctgtt ggagtgataa
    16441 ccactttgtc acccacatgg attccagata atgtagtccc gtacgttccg atttttgctg
    16501 ctccaccatt gactgtataa gaaaaagttc ctgtccgatt cgcattgacc tgaaccgttg
    16561 ctgcttgata ggttggaaaa tttgaaacat ttcccttacc atcaacgatc tgcccatttt
    16621 tgatcgagta ccccgtgaat ggaatatcat ttgctaactg tataccgatt gaaaaagtac
    16681 tcatacctcc tccggcagga agccctcccc atgttgaggg tgtaaaagaa taacttttat
    16741 ccgcattggg tgtaactgaa tcgatcgtat ttccagcggt agccaccccc atatagatac
    16801 tttttgggaa tgtgatagta gtaccattta ctgtggagcc aataaacaga ttatggatat
    16861 ctggacggtt atcaataaaa gcgattgctt tggttacgcc ttgtaacgca gttttatccg
    16921 cactcatcga tccgttaacc gcaacaatga ctccatcttt ggcatatatc actgtatatc
    16981 catctggtat ggtatgtccg ttgaaattcg cagtggccgc aacagtacta aatgtctggc
    17041 ttctacctgt ttctgaataa gctttctccc ctgctgcttt tgctgctgtg atttcttttt
    17101 ctgtcggatc aatcagttga gtcgaggatg tggttgaggt tgtctcgttg ttgctagact
    17161 gattggtgct ttctatggac tgtatttcag aatagggtgg actatttgtc tcctctgtcg
    17221 tttggttagc aaaatttgac gtttctgtat aaacgtttac ataaatactt gataagctcc
    17281 ctaagaaagt aaaaatcaag atgatcgaaa tcataatggg atgtaagtat tttcttttag
    17341 atacagcttt gagtctagaa acaaaatgtt tttgacatat acgttggatt ttattttgag
    17401 ttttcttaat cattttcatc cctcctctca ataaaaaatc atcaaataat cctttacacg
    17461 ttattctaaa tttaattttt attattttat tgatgtatag aaagtttggg gctttttttc
    17521 tctttttatt ctaaggttat tttagtcttg tcctttaata caaagatttt atttttaaa
//
LOCUS       DAZKKZ010000060        15822 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.061, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000060 DAZKKZ010000000
VERSION     DAZKKZ010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15822)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15822)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15822
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.061"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(57..359)
                     /locus_tag="ACG8LA_002193"
     CDS             complement(57..359)
                     /locus_tag="ACG8LA_002193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5960 family protein"
                     /protein_id="HFQ0204475.1"
                     /translation="MLMEGKTQLWFKFDPSNRFVKDFYKVWDSEVFFLAIEDSLLINL
                     YYSNKNYFKIPATKTRMKKDVYFLFDIVTDVPDARSDHRRYDYLKYTFVDPERYKD"
     gene            complement(579..945)
                     /gene="ssrA"
                     /locus_tag="ACG8LA_002194"
     tmRNA           complement(579..945)
                     /gene="ssrA"
                     /locus_tag="ACG8LA_002194"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(1116..1889)
                     /locus_tag="ACG8LA_002195"
     CDS             complement(1116..1889)
                     /locus_tag="ACG8LA_002195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFQ0204476.1"
                     /translation="MSNYRAITFFDLDGTLLDAKSKITPEVAKAMNALKENNVLPVIA
                     TGRTEAEIHSIMEDAGITSAVTMNGSFIRVDGEEIYSQTFSSEECQKMYDHVQLNGHE
                     LSYYNDQKIWCTGHSQTMINAYDFIHSDVPEIDPLGFKENTVNMLLILSQSGDEYYHE
                     HFPELTFYRNGPYSIDTVKKGISKGAGVKRLQKELQLEKVPTFGFGDGPNDFALLEAC
                     DNKIAMSNAYDGLKELSTFITKKNTEGGIVHALKYFDLI"
     gene            2033..2383
                     /locus_tag="ACG8LA_002196"
     CDS             2033..2383
                     /locus_tag="ACG8LA_002196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HFQ0204477.1"
                     /translation="MIFFSIGILFLIIGSLFRILPSKGNLPFYGYHSPLAAKTDAHWR
                     LAQKTSGNWFFLMGLLMALIGYYLKTSGHTNYFLIEMLLLVFPIMPIFIMTEKKLQKY
                     DLETGGNDNEYFND"
     gene            2364..3080
                     /locus_tag="ACG8LA_002197"
     CDS             2364..3080
                     /locus_tag="ACG8LA_002197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
                     /protein_id="HFQ0204478.1"
                     /translation="MNILMIEDNQSVSEMMQMFFLNEGWEATFKYDGKEGLDAFLENP
                     QHWDMITLDLNLPTLDGMLVGREIRKVSSTVPIIMLTARDSESDQVIGLEMGADDYVT
                     KPFSPLTLIARMKALHRRSELAEAREEAVVSDDHFDIETSHFKMNTKTREAYLDNRPI
                     EGLTPKEFDLLFTLAKKPRQVFSREQLLELVWDYQYFGDERTVDAHIKKLRQKIEKVG
                     PQVIQTVWGVGYKFDDSGVA"
     gene            3080..4528
                     /locus_tag="ACG8LA_002198"
     CDS             3080..4528
                     /locus_tag="ACG8LA_002198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFQ0204479.1"
                     /translation="MRYLYQQLLAFCGMVALILLIVGVSFTQLTKQTIEENNYQQLFG
                     YAESVEKTTQTYADTLPQFSQDQAFQNALLLTEQVLTEQNVNFIFIDKNERVIYPTNT
                     ALLNFTLTADQWKNLRNGRQEKFTSNKNILGQAQATSYALVPFNLNHEFYGALVVSQP
                     ARNIDNSVRPITLNLFKGFIFSSIVAVIASYAFAAFQVKRINRLRNATKEVTNGNFDV
                     QLPVHDKDEFDELADDFNKMTNSLKESQAEIEEQENRRRQFMADASHEMRTPLTTING
                     LLEGLEYNAIPENQRENAIKLMKNETERLIRLVNENLDYEKIRTNQISMVIKKFNGTE
                     TLKNIVAQLEAKAEAAGDTLTLKAVDDIDVYADYDRFVQIMVNIIQNAIQFTENGQIT
                     ITLEKGYLETIITIEDTGIGMSEQQMKSIWDRYYKVDPSRKNTKYGESGLGLPIVQQL
                     VRLHKGKLEVESELGKGTKFAVRLPDVEIKKE"
     gene            complement(4598..5107)
                     /locus_tag="ACG8LA_002199"
     CDS             complement(4598..5107)
                     /locus_tag="ACG8LA_002199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204480.1"
                     /translation="MKPEYLIHAEHLTVILCPLEKQHKILEHLKKEVLVAKLDNFAII
                     QKNWPMFPYLNLKDHVLLDVPEKEIKQDRLAYQEKLDISPSLLNCAAAELTSFEKVKL
                     QLLHALLSKRNNIVIEDTFDELSVLEIQELLHLLSYLAHEENQGILLFTHDATIAQSP
                     YIDRLEPAG"
     gene            complement(5097..5822)
                     /locus_tag="ACG8LA_002200"
     CDS             complement(5097..5822)
                     /locus_tag="ACG8LA_002200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204481.1"
                     /translation="MKIIRYATARLIYYKKQTILYCLFSSFSAFLLIACLTLYHLQSA
                     LANQVQDRLSFIGASASTELLPALELASRFYIKGIFSLFFLFAFLFIFFFYYSVRQNK
                     QELINWHLTGLSKTKLFLFIFWQLFFPLFLCCILVLLWIVSFQSVYEALLQRINFLVL
                     KTTELPDIRDILTSVSGLTIPMDQQTFFTIDFQNDLFFTDILKGFAQTLIGLSGCCLI
                     LSLFPFTFFIHHLQSRRPGRNET"
     gene            complement(6045..8165)
                     /locus_tag="ACG8LA_002201"
     CDS             complement(6045..8165)
                     /locus_tag="ACG8LA_002201"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008484 - sulfuric ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HFQ0204482.1"
                     /translation="MKCIKTPAFLNKRLGFFSLLVVLLWLKTIFAYLVDFHLGIESGI
                     QYFILFINPIATTLLLLGIALYIRRPRVAYITMMVIYFLLTLLVFSNVTYYREFTDFI
                     TINTILGAGKVASGLGESAIRLFRPYDVIYWIDFIILTVLLIAKKIKLDPRPIRARMA
                     FAISTLAVMIFSGNLFMAEADRPELLTRTFSRDYLVKYLGLNAFMVYDGVQTYQTNQV
                     RAEASPNDMKEVENYVKEHYAAPNDDLFGLARGKNVIYIHLESFQQFLIDYKLTDENG
                     LQHEVTPFINSLYHSNSTFSFDNFFHQVKAGKTSDAETLMENSLFGLNQGSLFTQLGG
                     KNTFQAAPDILSQTQGYISAVFHGNAGTFWNRNETYKNLGYDYFFDSSYYDVNDDNSF
                     QYGLHDKPFFQQSVQYLERLQQPFYSKFIAVSNHYPYSKFTNDEAGFPLANTNDETIN
                     GYFATANYLDTAVQEFFNYLKESGLYDNSVIVLYGDHYGVSNSRNKNLAELVGKTSST
                     WTNYDNAQMQRVPYMIHIPGQTQGGINHTYGGQVDALPTLLHLLGVDTKNYIQLGQDL
                     FSKDHEQLVSFRDGDFVTPKYTYYGGTIYSNETGEAITEPTEEVQNEIDSLKEKVDKQ
                     LAVSDQINNGDLLRFYTNSGLDPIDTSDYDYKNGLEKLKEAEKSLGDKSTSVFSEHNG
                     QSTVDLYKTQTYQELHGTTTSSSE"
     gene            8395..9573
                     /locus_tag="ACG8LA_002202"
     CDS             8395..9573
                     /locus_tag="ACG8LA_002202"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HFQ0204483.1"
                     /translation="MKVKVKKRASNRLKKGYPLIQKEDLAHPQKETTQWVELVDSQNQ
                     FIAKGYLGKQNKGIGWVLSQQNIPFDQSFFEEFFVKSKEKRTFFFSDDSTTAFRIFNG
                     EGDGIGGLIVDYYAGYAVFSWYNETLYAHRELLIQAFREIYPEIIGGYEKIRFESVNL
                     PESQFIYGKEAPEPLIVKENGVKFAVYLNEGLMTGIFLDQKEVRGSLAEGFASGKTVL
                     NMFSYTGAFSVAAAMGGAIETTSVDLAKRSLKKTQEQFEVNGLDVDQQKIIVMDVFEY
                     FKYAKRKQFLYDMIVLDPPSFARNKKKVFRVAKDYGELVKDSLDILAEDGILIASTNA
                     ANVSIEQFQTMIEEEFHAKNVSFEQLALYRLPKDFQTTDTFLEGNYLKVFVYQIKNNH
                     "
     gene            9589..10347
                     /gene="aroD"
                     /locus_tag="ACG8LA_002203"
     CDS             9589..10347
                     /gene="aroD"
                     /locus_tag="ACG8LA_002203"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003855 - 3-dehydroquinate dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HFQ0204484.1"
                     /translation="MVRVKGLNIGSGRPKICAPLIGAVREEVLREAVLAREAGADLVE
                     WRVDHYREVFSFDEVAETLVLIHEMLDGLPLLFTFRTLAEGGEQDISIRQYRDLYEHV
                     IHTGLVDMVDIELFKVESLGKRLIEEIKSLNIPLIISSHDFKETPADPVLLYRLNVME
                     HFGADIGKLAVTPNNERDVLRLMELTRRANAFVSMPIITMSMGNLGKISRLVGGTTGS
                     VMTFGSLSSDSTSAPGQLPVKALKQIIQLLNEPL"
     gene            10370..10855
                     /gene="ybaK"
                     /locus_tag="ACG8LA_002204"
     CDS             10370..10855
                     /gene="ybaK"
                     /locus_tag="ACG8LA_002204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0002161 - aminoacyl-tRNA editing activity
                     [Evidence IEA];
                     GO_process: GO:0043039 - tRNA aminoacylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro) deacylase"
                     /protein_id="HFQ0204485.1"
                     /translation="MAKKKIVKTNAIRMVEQKKIPYTEHEYEWDESHLSASSVAEQLP
                     ESQSRIFKTLVAVGNVTGPLVAVIPGEAELNLKKLAKVSGNKKVEMLHLKDLEATTGY
                     IRGGCSPIGMKKLFPTYLDQIAESYEQIIVSAGRRGLQMELAPQDICALTSGQFADIK
                     Q"
     gene            complement(10926..12179)
                     /locus_tag="ACG8LA_002205"
     CDS             complement(10926..12179)
                     /locus_tag="ACG8LA_002205"
                     /EC_number="1.14.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HFQ0204486.1"
                     /translation="MEKLYDVIVVGAGTSGMMAAISAAEQGARVLLIEKNKKAGKKLL
                     MTGGGRCNVTNNRPVDDLIAHIPGNGKFLYSTFAQWNNFDIMNFFESQGVHLKEEDHG
                     RMFPVTNKSKTIIEALLNRLKELDVTLLFSTRVEKLIHKEHKIYGIRTEFEEFHAPAI
                     ILTTGGRTYPSTGSTGDGYKIVKRVGHTVTPLYATESPLISDEPYIQEKTLQGLSLQD
                     ITLRVLNKKGRVLTEHTMDLLFTHFGISGPAALRCSSFVNKELEKTGEPVTLSLDCFP
                     TQTKQELIHILTEKSKATKKNLVNAWHGILPERLLVFFLERLEMDHLTGQQASQKQIQ
                     DFVQLCKEFKLSINKTFPIEKSFVTGGGVSLKEIYPKTLESKIIDGLYFAGELLDVNG
                     YTGGFNITAAFATGHVAGMNAGQRA"
     gene            12296..13645
                     /gene="gdhA"
                     /locus_tag="ACG8LA_002206"
     CDS             12296..13645
                     /gene="gdhA"
                     /locus_tag="ACG8LA_002206"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016639 - oxidoreductase activity, acting
                     on the CH-NH2 group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HFQ0204487.1"
                     /translation="MTNATEYVQAIQEKLHQKDQGQEEFLQAIDEFMPTVMSFLDTHP
                     EYIEKNILELLTEPERVIQFRVPWQDDEGNWRVNRGYRIQYNSAIGPYKGGLRFHPSV
                     NLSILKFLAFEQIFKNSLTGLPIGGGKGGSDFDPKGKSDNEIMRFCQSFMLELSKHIG
                     PSIDVPAGDIGVGAREIGYLFGEYKRLKKYDTGVLTGKPLDFWGSKIRTEATGYGLVY
                     YVKHLLNEEKDSFNQKTVFVSGSGNVAIYAIEKVQELGGKVVTCSDSSGYIYDPEGID
                     VKLLKEVKEINRQRLTEYANQRPSAIYHAGESVWTLKEKADIALPCATQNEIDESLAE
                     ILVENGIKIVAEGANMPCTVKAVSVLHEAGVWYCPGKAANAGGVAVSALEMSQNVQRL
                     TWEREQVDEQLDQIMETIYHTCRQTAAEYGDEKNLLLGANVAGFEKVAKAMAAEGLV"
     gene            13757..15103
                     /locus_tag="ACG8LA_002207"
     CDS             13757..15103
                     /locus_tag="ACG8LA_002207"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004347 - glucose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HFQ0204488.1"
                     /translation="MAHIHFDYSKVAPFVNEQELGYMQSQVTAAHNELREGTGAGSDF
                     RGWIDLPTNYDKEEFARIKEAAKKIQSDSEVLVVIGIGGSYLGARAAIDFLNHTFFNL
                     LDSNTRKAPQIFFAGNSISSTYIADLIEVIGDRDFSVNVISKSGTTTEPAIAFRVFKE
                     LLVKKYGQEEANKRIYATTDKAKGAVKVEADAEGWETFVIPDDIGGRFSVLTAVGLLP
                     IAVSGADIDALMQGAADASKAYSSDKLEENEAYQYAAMRNILYRKGKVTELLINYEPG
                     MQYFSEWWKQLYGESEGKDQKGIYPSSANFSTDLHSLGQFIQEGRRNIFETVVKVEKP
                     RKSITIPEQAEDLDGLGYLQGKEVDFVNTKAFEGTLLAHTDGDVPNLLVKIPEMDAYT
                     LGYTMYFFEIAVGISGYLNGINPFDQPGVEAYKKNMFALLGKPGFEDLAKELNERL"
     gene            complement(15411..15797)
                     /locus_tag="ACG8LA_002208"
     CDS             complement(15411..15797)
                     /locus_tag="ACG8LA_002208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HFQ0204489.1"
                     /translation="MKKILGLIVIILIAFIGWKGWDYYQSTYVGKDYYAVVKAPMPAE
                     TDIKADNGEVIGRGFKYNVDAYAENGEKRQLDFDVITSGDSANGSAYPEGTILQLKAS
                     EKRIIEKKVITSDKVPSSVKEKLGLS"
BASE COUNT         5172 a         2828 c         3180 g         4642 t
ORIGIN      
        1 ttttataagt atggtgataa aatccgttcc gggctacctt ttttaggtag cctactttaa
       61 tctttatacc tttctggatc aacgaaagta tacttcaaat agtcataacg ccgatgatcg
      121 ctccgtgcgt ctggcacatc agtcacgata tcaaacaaaa aatacacatc tttcttcatt
      181 ctggtttttg ttgccggaat tttaaagtag ttcttattag agtaatagag attgattaat
      241 aagctatctt cgattgctaa aaagaaaact tctgaatccc acaccttata aaaatctttg
      301 acaaatctat tcgaaggatc aaatttaaac cataattgtg tttttccttc catcaacata
      361 atgttcacct caaaaagagt atacgaacta atgttctttt tgtaaagtag gaatatcatt
      421 gataatatgg atggaacata tatattaaaa agtgttcttt ttgaatgcta ttttgaatgc
      481 cattttcatt catttaacga aaatctgcga aaataaaaaa tgctcaaacc cttataaaat
      541 aaggatttaa gcatctagcg aaatctgctg aaatctcaca atggagacgg cgggagtcga
      601 acccgcgtcc aaacacatcg ccacttaaaa atctacgttc atagtcaact catttaagga
      661 ttcactttac agcttgccga gtgacaggca ttctgtatcg ctagtctgat gttctctttt
      721 tcaacttaca gacggaaagt tgaaacgtat cccactaaag ttaggaccct tactcgagca
      781 catgggcgat gccgagagga tctacgctaa ctgtttttag gcagctaaag cgtaagagtt
      841 gttttcgttt ttagcagtta tatttaactg taacgttttt acgtagacgt aacctacgaa
      901 acgcaattca agctcgactg tgcctgtcga atccgtaacg tccccgttag ctaacaaggg
      961 ttacgtgtat ttttcataca aaattagtat agcatatatt gggataaatt caataaaaaa
     1021 gcgaatcata tcccattatt tatataataa ctgccccttt cttaagaaaa aataagcgat
     1081 tttcttaaga aaagaggtag cttcaaaaaa agatcttaaa tcagatcaaa atacttcaat
     1141 gcgtggacaa ttccgccttc tgtatttttc tttgtgataa aggtagaaag ttcttttaat
     1201 ccgtcatagg cgttgctcat agcgattttg ttgtcgcaag cttccaacaa ggcaaaatca
     1261 ttcggaccat cgccaaatcc aaaagtagga actttttcca gctgaagttc tttttgcaga
     1321 cgtttgacac ctgccccttt tgagattcct ttcttcactg tatcgatcga gtaaggacca
     1381 ttccgataaa aagttagctc aggaaaatgt tcgtgatagt attcgtcacc tgattgagat
     1441 aagatcagca acatatttac tgtgttttct ttaaagccta aaggatcaat ttccggaaca
     1501 tctgaatgaa tgaagtcgta agcattgatc attgtttggc tatgaccggt acaccagatt
     1561 ttctgatcgt tatagtaaga aagttcatga ccgttcaact gtacatgatc atacattttt
     1621 tgacattctt ctgaagaaaa tgtttgagaa tagatttctt cgccgtctac tcgaatgaaa
     1681 gaaccattca tggtgaccgc agaagtaatg cccgcatctt ccatgataga gtggatttct
     1741 gcttctgtac gtcctgtagc gatgacgggg agaacattgt tttcttttaa tgcgttcata
     1801 gcttttgcca cttcgggtgt gatttttgat ttcgcatcta gtaatgttcc atcaagatca
     1861 aagaaagtga ttgcacgata atttgacaca aataaaactc cttttttatt ggaataagtt
     1921 tatcttaaca aagaatgaac aaaagacaaa cctttcgtga agaattcctg aacatattgg
     1981 ttcagtcaac aatttagagt atactataag aagagaattt aggagggaaa gaatgatttt
     2041 tttcagtatt ggtatcttat tcttaataat tggcagtctt tttcggattc tgccctcaaa
     2101 aggaaatctg cctttttatg ggtatcattc gcctcttgcc gcaaaaacag acgctcattg
     2161 gcggctggct caaaagacaa gcggaaactg gttttttctt atgggcttac tgatggcatt
     2221 gatcggctat tatttaaaga catctgggca tacgaattat tttctgattg aaatgcttct
     2281 gctagtattt ccaattatgc ctatttttat tatgacagaa aagaaattac agaaatatga
     2341 cctggaaact ggagggaacg ataatgaata ttttaatgat tgaagataat caatctgttt
     2401 ctgaaatgat gcagatgttt ttcttaaatg aaggttggga agcaactttc aagtatgatg
     2461 gaaaagaagg gctcgatgcc tttttagaaa acccacaaca ttgggatatg attacactag
     2521 acctgaattt gcccacactg gacggtatgc tagtaggaag agagatccgc aaagtttcaa
     2581 gtactgtgcc gattatcatg ctgacagcta gagattctga aagcgatcag gtgatcggct
     2641 tagagatggg ggcagatgat tatgtcacaa aacctttcag tcctctgacg cttattgctc
     2701 gaatgaaagc tttgcatcgc cgtagtgagt tggcagaagc aagagaagaa gcagtagttt
     2761 cagatgatca ttttgatatc gagactagtc atttcaagat gaatacgaaa acacgagaag
     2821 cgtatctgga caaccggcca attgaaggac tgacgcctaa agagttcgat ctattgttta
     2881 ctttagcaaa aaaaccacgt caagtattct ctcgggagca gttgcttgaa ttagtctggg
     2941 attatcagta ctttggtgat gaacggacag tggacgccca tatcaagaaa ttacgacaaa
     3001 aaatcgaaaa ggtcggacca caagtcatcc aaactgtttg gggagtcggc tacaaattcg
     3061 atgattctgg tgttgcctaa tgcgttattt gtatcagcaa ctcttagctt tctgcggaat
     3121 ggtcgcgttg atcttattga tcgttggagt ttcttttaca caactgacaa aacaaacgat
     3181 tgaagaaaac aattaccagc aactgtttgg atatgctgaa tcagttgaaa agacaacgca
     3241 aacctatgcc gatacgctcc cgcagtttag tcaagatcag gcgtttcaaa atgcattgct
     3301 gctgacagag caagtactga cagaacaaaa tgtgaacttt atatttatcg ataaaaacga
     3361 acgtgtcatt tatccgacta atacagcttt actgaatttt accttaacag ctgatcaatg
     3421 gaaaaatctg aggaatggac gtcaagaaaa attcacatcg aataaaaata ttttaggaca
     3481 agcacaggcg acctcttacg cacttgtgcc atttaatttg aatcatgaat tctatggagc
     3541 acttgtagtt agtcaacctg cgcgaaatat cgataacagc gttcgtccaa ttacactgaa
     3601 cctgttcaaa ggatttattt tttccagtat cgttgcagtt attgccagct atgcttttgc
     3661 agcattccaa gttaagcgta tcaatcggtt aaggaatgcg acgaaagaag tgacgaatgg
     3721 taattttgat gtacagctcc ccgtacatga caaagatgaa tttgatgagt tagcagatga
     3781 tttcaataaa atgacgaatt cattgaaaga atctcaagca gaaattgaag aacaagaaaa
     3841 tcgtcgaaga caatttatgg cagatgcttc tcacgagatg agaacacctc ttacgacaat
     3901 caacggactt ctggaagggt tagaatacaa tgcaatccct gaaaatcagc gagaaaacgc
     3961 gattaaattg atgaaaaatg aaacagagcg tctgatccgt ttggtgaatg aaaacttgga
     4021 ttatgaaaaa atccgtacga atcaaatcag tatggtcatt aaaaaattca atggaacaga
     4081 aacattgaaa aatattgttg cacagttaga agctaaagca gaagcagcag gagatacatt
     4141 gacattgaaa gccgttgatg atattgatgt ttacgctgat tatgaccgat ttgtccaaat
     4201 catggtcaat attattcaaa acgcgataca gtttactgaa aacggccaaa tcacgattac
     4261 tttagaaaaa ggctatcttg aaacgatcat cacgattgaa gatacgggaa ttggaatgtc
     4321 tgaacaacaa atgaaaagta tctgggatcg ttattataaa gtagatcctt caagaaaaaa
     4381 tacaaaatat ggtgaatcag gattaggttt accaatcgtg cagcaacttg tacgcttgca
     4441 taaaggaaaa ttagaagtag aaagcgaact aggaaaagga acaaaattcg ctgttcgttt
     4501 gcctgacgta gaaatcaaaa aagagtaaaa aacaagcggt ataaaagatc atgaatcgat
     4561 cttctatacc gcttgttttt actataaaat gattgattta gcccgcgggc tctaaacgat
     4621 caatataagg actttgagca atagtagcat catgagtaaa gagtaagata ccttgatttt
     4681 cttcatgagc taaataagaa agcaagtgga gtagctcttg gatctccaat acactaagtt
     4741 catcaaatgt atcttcaata acaatattgt ttcgcttgga aagcaaggca tgaagtaatt
     4801 gcagctttac tttttcaaaa gacgtcaact cagctgccgc acaattaagc aaggaaggag
     4861 agatatcaag tttttcttga taggccaaac gatcttgttt gatttctttt tccggtacat
     4921 ccaacaggac atggtcttta agattcagat aaggaaacat cggccaattt ttttggatga
     4981 tcgcaaaatt atccagtttt gcaacaagaa cctctttttt caagtgctcc aatattttat
     5041 gctgtttttc gagaggacac aaaataacgg tcaagtgttc agcatgaatc aaatattcag
     5101 gtttcattac gtccaggcct cctactttgc aaatgatgga taaaaaaagt gaaagggaat
     5161 agactaagaa tgagacagca tccactgagc ccaataagag tttgggcaaa tcccttaagt
     5221 atatctgtga aaaaaagatc attttggaaa tcgatggtaa aaaaagtctg ttgatccatc
     5281 ggaattgtaa gtccgcttac cgaagtcaag atatcacgga tatctggcag ttcagtagtc
     5341 tttaagacaa gaaaattgat cctttgaaga agcgcttcat aaactgactg gaagcttacg
     5401 atccacaata aaaccaagat acaacaaaga aagagaggaa agaacagctg ccagaaaata
     5461 aaaaggaata atttggtttt agaaagacca gtcaggtgcc aattgatcaa ttcctgcttg
     5521 ttttgcctga ctgaatagta aaagaaaaag ataaaaagga aggcaaatag aaaaaataaa
     5581 ctgaatatgc cttttatata aaatcggcta gctaattcta aagccggaag aagctctgta
     5641 gatgcagaag cgccaataaa tgaaagccga tcttggactt gattggctaa agccgattgc
     5701 aaatggtaaa gagtcaggca tgctatcaat aaaaaagcag aaaagcttga aaataaacaa
     5761 tagagtattg tctgcttttt gtaataaatt aatcgagcag tagcatagcg gattattttc
     5821 atacttttca cctctataaa aagtatagaa aatgaatatg aataaagtat gaaattcctt
     5881 tagtgaaatc acgaattaaa accagaaaat attttgtaaa aagcaagagg ttgtgaagaa
     5941 gctgccctat tctattaccg tagatgcaag cttttgaaca ctgtttattc gaaaagagga
     6001 gcagcgacaa taattttgtc gctgctcctt ttaaatttat tttatcattc ggaagaactt
     6061 gtggtcgttc cgtgaagttc ttggtacgtt tgcgttttat aaagatcaac agttgattgt
     6121 ccgttgtgtt cactaaagac actagttgac ttgtcaccaa gagatttttc agcttctttt
     6181 aatttctcta agccattctt gtagtcataa tcactggtat caattgggtc taatccacta
     6241 ttcgtataga accgaagaag atcaccatta ttgatttggt cagaaacagc taactgttta
     6301 tcaacttttt ctttcagtga atcaatttca ttctgtactt cctcagtagg ttcagtaata
     6361 gcttcaccag tttcgttact atagatcgta ccaccgtagt aagtatattt tggtgtaaca
     6421 aaatcaccat cacggaaaga aacaagctgt tcatgatctt tcgagaatag atcttgtcct
     6481 aactgaatat aattttttgt atctacacct agtaagtgaa gtaatgtagg caaggcatca
     6541 acttgtccgc cgtaagtgtg attgattccg ccctgtgttt gtccagggat atggatcata
     6601 taagggacac gctgcatttg tgcattgtcg tagtttgtcc aagtagaact tgtttttcca
     6661 actaattcag ctagattttt atttcttgaa ttcgagacac cgtaatggtc accgtaaagg
     6721 acgatgactg aattatcata caagccgctt tctttcaaat aattgaagaa ttcttgtacg
     6781 gcggtatcta aataattggc tgtcgcaaag taaccgttga tcgtttcatc atttgtattg
     6841 gctaacggga atcctgcttc gtcattggtg aattttgaat aaggataatg gttagataca
     6901 gcaatgaatt ttgaataaaa tggttgttgc agacgttcca agtattgtac ggattgttgg
     6961 aaaaatggtt tatcatgcaa cccgtattgg aacgaattgt catcattaac atcataataa
     7021 gaagaatcaa agaaataatc atatcctaaa ttcttgtatg tctcgtttcg attccagaat
     7081 gtaccagcgt tcccatggaa taccgcacta atgtaacctt gtgtttgact taaaatatca
     7141 ggtgcagctt ggaaagtatt ttttccgcct aattgtgtga acaaggagcc ttgattcaag
     7201 ccaaacaatg aattttccat cagcgtttcc gcatcgcttg tttttcctgc ttttacttga
     7261 tggaaaaagt tgtcaaaact gaacgtgctg ttgctgtggt aaagactatt gatgaaaggt
     7321 gtaacttcat gctggagacc attctcatct gtcaatttat aatcgatcag gaattgctgg
     7381 aagctttcta aatggatata aatcacattt tttcctctag cgagcccgaa caaatcgtca
     7441 tttggtgctg cataatgttc ttttacataa ttttctactt ctttcatatc attgggactt
     7501 gcttctgccc gcacttggtt tgtctggtaa gtttgaacac cgtcataaac catgaaagca
     7561 ttcaagccaa gatatttgac caaataatca cgagagaatg ttcgagtcag caattctgga
     7621 cgatcagctt ccgccataaa aagatttcct gagaaaatca taactgctaa tgtagagatc
     7681 gcaaaagcca ttcttgctcg gatcgggcga gggtccaact tgattttttt tgcaatcagc
     7741 agaacagtca agataataaa atcgatccaa tagatcacat catatgggcg aaacagtcga
     7801 atggcacttt ctcccagacc actcgctact ttcccagcac ctaaaatcgt gttgatcgta
     7861 atgaagtccg tgaattctcg ataataagtg acattcgaaa aaacaagcaa tgtcaaaaga
     7921 aaataaatga ccatcatcgt gatataagca actctagggc gtctgatata aagagcaatt
     7981 ccaagtaata acaatgtagt tgcaataggg ttgataaaca agataaagta ttgaatgcca
     8041 ctttcgattc cgagatggaa atcaactaaa taggcaaaaa tcgttttcaa ccaaagtaaa
     8101 acgactagta aagaaaaaaa tccgagcctc ttattcaaaa aggcaggtgt ttttatacat
     8161 ttcaagataa tcttcctttc tgcacttctt aatcacagaa gtgtcctgaa accatgttac
     8221 acagctcact tattctcatt tattttacta gtatgacaat atagtgtcaa ttgaaaccag
     8281 aagtttatgc tgtttcatta aggttttctt taagcttcat gaaaaaatga gcagtaagac
     8341 aagtcctatg ttttttgtta tacttgggaa gagaaagcta aagcaggtga aggaatgaaa
     8401 gtaaaagtaa aaaaaagagc aagcaatcga ttgaaaaaag gatatccact gatccaaaaa
     8461 gaagaccttg ctcatcccca aaaagaaacc acgcaatggg tggaattagt tgattcgcaa
     8521 aaccaattta tcgcaaaagg atatctagga aagcagaata agggaatcgg ttgggtattg
     8581 agccagcaga acatcccatt tgatcaatct ttttttgaag aattttttgt gaagtcaaaa
     8641 gaaaaaagaa ctttcttttt ttcagatgat tctactaccg cttttcgtat attcaatgga
     8701 gaaggagacg ggatcggcgg tctgattgtt gattattatg caggttatgc tgttttttct
     8761 tggtataacg aaacgttata tgcacatcgt gaattattga ttcaagcttt tcgtgaaatc
     8821 tacccggaaa tcataggagg ctatgagaaa attcgatttg aatcagtaaa tctgcctgag
     8881 agccagttca tttacggaaa agaggcaccg gaacccttga tcgtaaaaga aaacggagta
     8941 aaatttgccg tttatttaaa tgaaggatta atgactggga tctttttaga ccaaaaagaa
     9001 gtacggggat cattagcaga aggtttcgct tctgggaaaa cagttttgaa catgtttagt
     9061 tataccggcg ccttttctgt tgctgccgca atgggagggg caatcgaaac aacaagtgtc
     9121 gatctagcaa aacgcagttt aaaaaaaaca caggaacagt ttgaagtgaa tggtttggat
     9181 gtcgatcagc aaaaaatcat tgttatggac gtattcgagt atttcaaata cgccaaaaga
     9241 aaacaatttt tatatgacat gattgtattg gatccaccaa gttttgccag aaataagaaa
     9301 aaagtctttc gcgtagcaaa agattatggg gaactggtca aggatagtct ggatatttta
     9361 gcagaagacg ggatacttat tgcgtctaca aatgctgcga atgtctcgat agaacaattc
     9421 caaacaatga ttgaagagga attccatgcc aaaaatgttt cttttgaaca acttgcttta
     9481 tatcgtctgc caaaagattt ccagacgacg gatacctttt tagaaggcaa ttatctgaaa
     9541 gtgtttgttt atcaaattaa aaataaccat tagaaggagc gatgcagaat ggttcgggta
     9601 aagggattga atataggaag cggtagacca aagatttgtg cgcctcttat cggggccgtc
     9661 cgagaggaag tattacgtga agcagttctt gcacgtgaag caggggccga tttagtcgaa
     9721 tggcgagtcg atcattatcg tgaagttttt tcttttgatg aagtagcaga aacattggtt
     9781 cttatccatg agatgcttga tggactgccg ttattattta cgtttcgtac cttagctgaa
     9841 ggcggagaac aagacatatc gatccgtcag tatcgcgacc tttatgaaca tgtgatacac
     9901 acaggattag tagatatggt cgatatcgag ttgttcaaag tagaaagtct aggaaaaaga
     9961 ctgatagagg aaatcaagtc tttaaacatt cctttaatta tcagtagtca tgattttaaa
    10021 gaaacaccag cagaccctgt cttgctttac cgattgaatg ttatggaaca ttttggagcc
    10081 gatatcggaa aactggcagt aactcccaat aatgaacgag atgttttgcg gttgatggag
    10141 ttgactagac gggcaaatgc ttttgtctcc atgcctatta ttacgatgtc catgggaaat
    10201 cttggtaaaa tttctcgtct ggttggcgga acgacgggtt ccgttatgac atttggttcc
    10261 ttaagcagcg attctacttc tgctccagga caattaccgg tcaaagcatt gaagcaaatt
    10321 attcaattat taaatgaacc gttgtagaac aagtttgagg tgatattttt tggcaaagaa
    10381 aaaaatagta aaaacgaatg caatccgtat ggtcgaacaa aaaaagattc cctatacaga
    10441 gcacgaatat gagtgggacg aaagccacct aagtgcgtca tcggtcgctg aacagcttcc
    10501 agaaagccaa tctcgtatat ttaaaacact ggttgctgtg ggcaatgtga cggggcctct
    10561 tgttgctgtg ataccgggag aagccgaatt gaatctaaaa aaattagcaa aagtttcagg
    10621 gaataaaaaa gtagaaatgc tccatttaaa agatttggaa gcaacgaccg gatacatacg
    10681 tggtggctgc tcgcctatag gtatgaaaaa actatttcct acttatttag atcaaattgc
    10741 agaaagctat gaacaaatca ttgtctcggc tggcagaaga gggctacaga tggagttagc
    10801 acctcaagat atctgtgcat taacgagcgg acaatttgca gatataaaac aataaatcat
    10861 acgtataaaa gaaagaagga ggccgggatg ttgtttgtcc agtctccttc tttctttttt
    10921 atacattatg ctctttgccc ggcattcatt cctgctacat gccctgtagc gaaagccgct
    10981 gtgatattaa agccgccagt ataaccattg acatccagta attctcccgc aaaatacaga
    11041 ccatcaatga ttttactctc caatgtttta ggataaattt cctttagaga aacccctccg
    11101 ccagttacaa atgatttctc aataggaaaa gttttgttga ttgatagctt aaactctttg
    11161 catagttgaa caaaatcttg aatttgtttt tgagaggctt gttgtcctgt cagatgatcc
    11221 atttcaagcc gctcaagaaa gaaaactaac aatcgctcag gcaatatacc atgccaagca
    11281 ttgaccaagt tctttttggt tgctttactt ttttctgtca atatatgaat aagctcttgt
    11341 ttggtttgtg tagggaaaca atccagagaa agtgtcactg gttctcccgt tttctctaat
    11401 tctttattga caaaacttga acaacgcagt gcagccggac cagaaatacc gaaatgggtg
    11461 aaaagtaaat ccatcgtatg ttcagtcaat acacgacctt ttttatttaa aacgcgtaaa
    11521 gtgatgtctt gtaaagaaag cccttgaagt gttttctcct gaatatacgg ttcatccgat
    11581 atcaaggggg actctgtcgc ataaagaggc gtcaccgtgt gacccactcg cttcacgatc
    11641 ttgtacccat ctccagtaga accagtagat ggataagtcc gtccaccagt tgttaagata
    11701 atggcaggag catggaactc ttcgaattcc gtgcgtatac cgtaaatttt atgttctttg
    11761 tggatcaatt tctctactcg agtagagaat agaagcgtca catctagttc tttcagacga
    11821 ttgagcaatg cttcgataat cgtttttgat ttatttgtta caggaaacat ccgtccatga
    11881 tcctcttctt ttaaatgtac gccttgtgat tcaaagaagt tcatgatatc gaaattattc
    11941 cattgcgcaa acgtactata taaaaacttt ccatttccag gaatatgtgc aatcaaatca
    12001 tcaacaggac gattgttcgt aacattgcac cgaccaccac ctgtcatcag tagttttttt
    12061 cctgcttttt tgtttttttc gatcaagagt acgcgtgcgc cttgttcagc tgcactgatc
    12121 gctgccatca tcccgcttgt tccagcgccg actacgatca catcatacag tttttccatt
    12181 ccctcacctc aaggaaagtg tagcatatct gaagaaagaa aacagaaaaa aatgttttga
    12241 gccaaaagag aaaatgagct aaaatgaggg aagataagca aaggagcgtg gaacgatgac
    12301 aaacgcaaca gaatatgttc aagcaattca agaaaagcta catcaaaagg atcaagggca
    12361 agaagaattt ttacaagcaa tcgatgaatt catgcccacg gttatgtctt ttttggacac
    12421 tcatcccgaa tatatcgaaa agaatatctt agaactttta acggaaccag aaagagttat
    12481 tcaatttcga gtgccttggc aagatgatga aggaaactgg cgagtaaata gagggtaccg
    12541 tatccaatac aactcagcta tcggccctta taaaggtgga ttgcgcttcc atcctagtgt
    12601 caatctaagt atcttgaaat ttttggcttt tgaacagatt ttcaagaata gtttaaccgg
    12661 tctgccaatc ggtggaggaa aaggcggaag tgacttcgat cctaaaggaa aatctgataa
    12721 tgagatcatg cgtttttgtc aaagtttcat gctggaattg tcaaaacata tcggcccatc
    12781 gattgatgtt cctgcgggag atatcggtgt aggagctaga gaaatcggct atttgttcgg
    12841 cgaatataaa cgattgaaaa aatatgatac tggtgtgttg acaggtaaac ctttggattt
    12901 ttggggaagt aagatacgta cggaagctac tggttatgga ttagtgtatt atgtcaaaca
    12961 tctattgaac gaagaaaaag attcatttaa tcaaaaaaca gtttttgttt ccggaagcgg
    13021 gaatgtagcc atttatgcaa tcgaaaaagt gcaagagcta ggcgggaaag ttgttacatg
    13081 ttcagattct agcgggtaca tctatgatcc agaaggaata gatgtgaaac tattgaaaga
    13141 agtcaaagaa atcaatagac aacgtttgac ggaatacgca aaccaacgtc cttctgctat
    13201 ttatcatgct ggagaatctg tttggacatt gaaagaaaaa gcggatatcg ctttgccatg
    13261 tgctactcaa aatgaaatag acgaaagctt ggccgaaatc ttagtagaaa atgggatcaa
    13321 aatcgtagca gaaggcgcta atatgccatg tacagtaaaa gctgtttctg ttcttcatga
    13381 agcaggcgtg tggtattgtc caggaaaagc tgctaatgct ggaggagtag cagtatctgc
    13441 tttagaaatg agtcagaacg tccagcgatt gacttgggaa agagagcaag tggatgagca
    13501 gctggatcaa atcatggaaa cgatttacca tacgtgtcgc caaacagcag ccgagtacgg
    13561 cgacgaaaaa aatctgcttc ttggagcaaa tgttgctgga tttgaaaaag ttgccaaagc
    13621 aatggcagca gaaggtttag tttgaaaaat gaaactttct tggaaatatt gtcagcattt
    13681 tgtttatttg cttgaaaaat aataaaaaaa aacgtaaagt attacctgta gagtaaacct
    13741 ataaggagga gaacaaatgg cacacattca ttttgactat tcaaaagtag caccgtttgt
    13801 caacgaacaa gagttagggt acatgcaaag ccaagtaaca gcagcccaca acgaattacg
    13861 ggaaggtact ggcgcaggaa gcgacttccg cggctggatc gatttaccaa cgaactatga
    13921 caaagaagaa tttgcacgta tcaaagaagc agctaaaaaa atccaatctg attctgaagt
    13981 attagttgtt atcggtatcg gtggttctta tttaggcgct cgtgcagcga tcgacttctt
    14041 gaatcacaca ttcttcaatt tattagatag caacacaaga aaagcaccac aaatcttctt
    14101 tgccggaaat tcaatcagct caacatatat tgctgacttg atcgaagtaa tcggtgatcg
    14161 cgacttttca gtaaacgtta tttcaaaatc tggaacaact actgaaccag cgattgcgtt
    14221 ccgtgtattc aaagagcttc ttgttaagaa atatggacaa gaagaagcaa acaaacgtat
    14281 ctacgctaca acagataaag caaaaggtgc agttaaagta gaagcagatg cagaaggttg
    14341 ggaaactttc gtgattcctg atgacatcgg cggacgtttc tctgtattaa ctgctgttgg
    14401 tttgttacca atcgctgtta gtggtgcaga tatcgatgca ttgatgcaag gtgccgctga
    14461 tgcaagcaaa gcatactcaa gcgacaaact agaagaaaac gaagcttacc aatacgcagc
    14521 aatgcgcaac attctttacc gtaaaggcaa agtaactgag ttgttgatca actatgaacc
    14581 aggaatgcaa tacttctcag aatggtggaa acaattgtat ggtgaatctg aaggaaaaga
    14641 ccaaaaaggc atctatcctt caagcgcaaa cttctcaact gatttgcact ctttaggaca
    14701 attcatccaa gaaggacgtc gcaatatttt tgaaacagtt gtgaaggttg aaaaacctcg
    14761 taaatcaatc acaattcctg aacaagcaga agatttagac ggtctaggct acttgcaagg
    14821 aaaagaagtg gacttcgtaa atacaaaagc atttgaagga acattgcttg ctcatacaga
    14881 cggtgacgtg cctaacttgc tagtcaaaat tccagaaatg gatgcttata cattgggtta
    14941 tacaatgtac ttctttgaaa ttgctgtagg tatttcaggt tacttgaatg gaatcaaccc
    15001 attcgaccaa ccaggtgtag aagcttacaa gaaaaacatg ttcgcacttc taggcaaacc
    15061 aggctttgaa gatcttgcta aagaattgaa cgaacgcctg taagataagg gtttttcgct
    15121 agatttaaat aatcagtgat agaaacatgt tcgctttaaa atgaaaactg gtacccattt
    15181 aggtactcaa acatactgca tcgtttattc agaataaggg gctgtgacaa gacgtttgtc
    15241 acagtccctt gtttgtatag aaatcgattg attgccttgc tctttagttt gttttaggac
    15301 tttaagaaca gtgaggctga cttcgaaggt taattctgtt tttttgtttt ctagaatcag
    15361 taagcaaaaa agcactcact tcgagtgctt ttttgcgata tattcttagc ttaagatagg
    15421 cctaattttt cttttacaga tgagggtacc ttatcgctgg taattacttt tttctctatg
    15481 atccgctttt cgcttgcttt caactgcaag atcgttcctt cggggtaagc agaaccattg
    15541 gcagagtcac cagaagtaat gacatcgaaa tctaactgtc ttttttcacc gttttcagca
    15601 taagcatcta cgttgtattt aaaacctctt ccaattactt ccccattatc tgctttgata
    15661 tcagtttctg caggcattgg agctttgact accgcataat aatctttacc tacataagta
    15721 gactgatagt agtcccaacc tttccatcct ataaaagcaa tcaatatgat aacgatcaac
    15781 cctaaaattt ttttcatgaa agatctcctt ttttattttt at
//
LOCUS       DAZKKZ010000061        15686 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.062, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000061 DAZKKZ010000000
VERSION     DAZKKZ010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15686)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15686)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15686
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.062"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(98..1084)
                     /locus_tag="ACG8LA_002209"
     CDS             complement(98..1084)
                     /locus_tag="ACG8LA_002209"
                     /EC_number="2.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004659 - prenyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HFQ0204490.1"
                     /translation="MKLHPMWENYPALSKELTETLKRMEETVRLKNKPVEQAIKETIH
                     AGGKLLRPAYQLLFSQFGPEQDRDKAIALAASIEMLHTATLIHDDIVDEADLRRGQPN
                     IRSQFGNVVSVYAGDYLFVCCFKLLSDYSTSLKSLQLNSRSMEKVLNGELGQMDDRYN
                     YELSVKEYLENISGKTAELFQLSCSVGAFESGTSERFAKKAGDIGLSIGMAFQIIDDI
                     LDYTKESQEIGKPVLEDMRQGVYSLPLIYSLQKNKPKLLPYLEKKAAMTEEDVDAVRK
                     IVEHTGGVEEARKLAASYTEKALKEIKKLPATSLRTKENLFSLTQLILDRKD"
     gene            complement(1107..1673)
                     /locus_tag="ACG8LA_002210"
     CDS             complement(1107..1673)
                     /locus_tag="ACG8LA_002210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gx transporter family protein"
                     /protein_id="HFQ0204491.1"
                     /translation="MSKLQKMIYISLLVAQGVIIGLLENMIPYPFSFAPGAKLGLANL
                     ITIVAIFTMKKQDSFLLLWLRLFLTTLLGGTISTFLYSMSGALLSYFGMLLVKQLGPK
                     RVSIIGISAAGGFMHNVGQLLMASFIAQSWTVMLYLPVLSVLGILSGIAIGIAANYLL
                     RHVQTLQRFQKDYEQGTKQKWSPMFTKK"
     gene            complement(1687..2103)
                     /locus_tag="ACG8LA_002211"
     CDS             complement(1687..2103)
                     /locus_tag="ACG8LA_002211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HFQ0204492.1"
                     /translation="MSLKEFAEKSLLKPWDVFIILLLTVLSFLPVMIFGLQQNTATAE
                     KEAVLRVDGTEIKTFPLMAGEESNTYTYKDEHGDYNLIEIDGDRVRIKEADCDDQICV
                     RRGWATKNGETIVCLPHKLVIEVRSTDGGDEDSLIY"
     gene            complement(2560..4494)
                     /locus_tag="ACG8LA_002212"
     CDS             complement(2560..4494)
                     /locus_tag="ACG8LA_002212"
                     /EC_number="1.6.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HFQ0204493.1"
                     /translation="MAKQNIVVVGAGYAGVSATKYLAKKLKKEDVAITLIDRHSYHTM
                     MTELHEVAGGRVEPEAIQYDLQHLFARQKNVQLVTDTVIGIDKERKIVKTKLGSYPFD
                     QLILGMGGEPNDFGTPGVKAHGFTLWSFEDSVRIREHIEKTVAKAALEPDDELRKAML
                     TFVVCGSGFTGIEMIGELIDWKNRLAKDYKLDPNEITLMVVEAMPTILNMLDRNDAAK
                     AERYLRKHNVELLLNAPIVEVAADHIKLKDGRNIPTHTLIWTAGVKGTSDAADFGLES
                     ARGQRLIANEYMQAKGYEDKNIYIIGDLVFYEEFPGTPTPQIVQAAEQTGHTAAANIV
                     ASIKGGEKHKFKGNYQGFMVSIGAKWGVANLFDKIHLSGFLAIVMKHIVNLKYFFDIR
                     SGYYMFQYLMHEFFHIKDDRNVTRGHSSRYGNVLWSVPLRIFYGLVWFVEASKKIIGN
                     GEVFKPSTWFGEGSWFTGNSVFPWTWEYNVTDVASGASAAGDATTAASGAGASAGEAA
                     TQAAHFGLSYAYGEEPMAVIEKSPDWFTKIMQVIMPNNDVAMFFQKFMVFFEIALALA
                     LIAGLFTWLCSATTIVLVITFCLSGMFYWVNIWFIFVAFALMNGSGRAIGLDRWVIPW
                     LQRTLGNWWYGRPSSQYGKK"
     gene            4796..5731
                     /gene="pplA"
                     /locus_tag="ACG8LA_002213"
     CDS             4796..5731
                     /gene="pplA"
                     /locus_tag="ACG8LA_002213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular electron transfer flavoprotein
                     PplA"
                     /protein_id="HFQ0204494.1"
                     /translation="MKKKRFVTGFAVLAFSALVLGACGADDNGSSNSSSESSTAQSST
                     AKSTTESSAKVVAGGDLQDGTYKLEEKNYSNGYRAVFEMVVKDGKITESKYDNVNENG
                     ESKTKDAEYNKNMEAKSGTNPEKYIPELNDQFLKAQSASGVEVVTGATHSSESFQNYA
                     QQLIQAAQAGNTDTIEIDNGADLKDGTYKLEEKNYSNGYRVQFEMTVAGGKVTESNFD
                     YIDKDGKSKQDDTEYNENMKAKSGTEPKTYIPTLNDEFVKAMGEEDGSPANVEVVTGA
                     THSSHSFIMYAQQLVNAAEKGDTQTIEVDNIVTEK"
     gene            5821..6924
                     /locus_tag="ACG8LA_002214"
     CDS             5821..6924
                     /locus_tag="ACG8LA_002214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0017013 - protein flavinylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HFQ0204495.1"
                     /translation="MRKKLLFSLITLGISFMVLTGCSNSANKTTTESSAATKILKDPY
                     SDEQFLLGTYVRIRVYDEGKESALKPAFDRVKELGDKITINQKGSEIDEVNEQAGIKP
                     VKVSDDVYTLVKRAYEYSQDSQGGFDMAIGAITQLWRIGFDDARKPSQEEIDQALKLV
                     DYHKIELNDKEKTVYLKEKGMIIDLGAIAKGYITDEVVKVLKKQGVTTAIVDLGGNVY
                     VLGHSPRGENQDWTVGIQDPNMARGSVLGSIKERNKTLVTSGIYERYLEVDGKKYHHL
                     FDPKTGYPFDNDIASVTIITDKSIDGDGLSTAVFSMGVKKGLEYVESELNNGTEAIFV
                     TKDDKVYVTDPIKDTFKLSEDSHYTMGDRSELK"
     gene            6937..7890
                     /gene="menA"
                     /locus_tag="ACG8LA_002215"
     CDS             6937..7890
                     /gene="menA"
                     /locus_tag="ACG8LA_002215"
                     /EC_number="2.5.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoate
                     polyprenyltransferase"
                     /protein_id="HFQ0204496.1"
                     /translation="MTLKIFLEVVEIRTKVASVFPFAVGVLFSIAFFHEIHWLNTFLF
                     FIGMLVFDLATTAINNYMDYEKAHSEVYKYEENVIGRRNLSPVLIRNMILAMIAFVFV
                     IGVILTINTGWLLLLMGFICCFIGVFYTFGPIPLSRMPLGEIFSGVTMGLGIFAMVVY
                     VNTFGSDVYDLTVNFSSGQFALVGNLWAIAAIVLASLPLVFTIANIMLANNLRDLDRD
                     IENHRYTLVFYIGRPAGTVLFQLLMYACYFVILMGLLSGIYEWPILVTFLTLPIVKKH
                     LDQFKQTLPQPISFSYSIKNMVLFNASYVLGLLLTIIMQAI"
     gene            complement(8704..10050)
                     /gene="gor"
                     /locus_tag="ACG8LA_002216"
     CDS             complement(8704..10050)
                     /gene="gor"
                     /locus_tag="ACG8LA_002216"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004362 - glutathione-disulfide reductase
                     (NADPH) activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006749 - glutathione metabolic process
                     [Evidence IEA];
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HFQ0204497.1"
                     /translation="MQIYDYIVIGGGSGGIASANRAGMHGAKVLLIEANELGGTCVNV
                     GCVPKKVMWQASTILETIERDASSYGIQADLKNVDFAGLVERREKYIDFLHGAYQRGL
                     DSNHVEAIKGYATFIDSQTIEVNGETYRAPKILIATGGRASKMTIPGGEYAIDSNGFF
                     ELTELPKRAIVLGAGYIAAELSGVFRGLGSEVMWAYRKERPLRTFDKMLSDNLIQMYQ
                     EAGIKTYAHHIAKEITKNNDEYTVLFENGETLTGDCVLFAGGRVPNTEKLGLENTNVE
                     LDKKGFIKVDKYQNTTDEHIFAVGDVIGKLDLTPVAIAAGRRLSERLFNGKKDSYLDY
                     KLVPTVVFTHPPIATIGLTEEEALEKYGENELKVYRSRFTPMYFALNDYRQKCEMKLI
                     CVGKEERIVGLHAIGVGVDEMLQGFAVAIKMGATKEDFDNTVAIHPTGAEEFVTMR"
     gene            complement(10184..11437)
                     /locus_tag="ACG8LA_002217"
     CDS             complement(10184..11437)
                     /locus_tag="ACG8LA_002217"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:1901576 - obsolete organic substance
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HFQ0204498.1"
                     /translation="MMKEMTVKRKLKRPEILAPAGTLEKLKTAIHYGADAVYIGGNAY
                     GLRSRAGNFTYEEMAEGVAFAKEHDAKVYVAANMVTHEGNEDGAGEFFRSLRDVGISA
                     VIVSDPALIEICATEAPGLPIHLSTQASATNFETLEFWKEEGLERVVLAREVSMEEVA
                     EIRKNTDTEIEAFIHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYGLFDMPFG
                     QERNSLTDTGEVEEEFSMSAVDMSMIEHIPELIENGVDSFKIEGRMKSIHYVSTVSNV
                     YKAAVDSYMEDPENYVCKQEWIDELWKVAQRELATGFYYNTPTENEQLFGERRKIPVY
                     KFVGEVLSYDEATQIATIRQRNLFSVGDEIEFYGPGFSHFSQTVEVMHNEEGESIDRA
                     PNPMMILTMPVAQPVKPGDMIRKRK"
     gene            complement(11443..12366)
                     /locus_tag="ACG8LA_002218"
     CDS             complement(11443..12366)
                     /locus_tag="ACG8LA_002218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase U32 family protein"
                     /protein_id="HFQ0204499.1"
                     /translation="MIELITTVETIEQAEQLLAAGADTLYFGEEQFGLRLPASFTREE
                     QRQLVELAHKYGKKANIAVNGIIHPEKMKNVPEYLAFLKEINVDVITVGDTGIIYTMK
                     KNPELRIPYIYDAETLVTSARQINFWAKKGAVGAVLAREVPFEEMKAMEEKLDIPVET
                     LVYGATCIHQSKRPLLQNYYNYTKQDEQKDRERGLFISEPKKEETHYSIYEDSHGTHI
                     FASNDLNLSNELNELYQHHYCTWKLDGLFTPGEKFVNITRLFAEAKKQILEGSWDQEK
                     AEKMTSEISKLHPENRELDTGFFYIDPSAIK"
     gene            complement(12587..15079)
                     /locus_tag="ACG8LA_002219"
     CDS             complement(12587..15079)
                     /locus_tag="ACG8LA_002219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HFQ0204500.1"
                     /translation="MEELFTERAQAVLEIAQEEAKRLKHQSVSSEHVLLALVVEQNGI
                     AGKVLREMDLNETEIYEEIEHLIGYGGIRSYPKGVFLPYSPRMKQVFALASSEVKKTG
                     SQKVGTEHILMSLLKDESIMATRIMINLGISLSKARQVLKQKMGLAGDSAGKGMNRRR
                     NVNVQDKRQTPQGTPTLDSLARDLTKLAKENKLDPVVGRSREVKRLIQILSRRTKNNP
                     VLVGEPGVGKTAIAEGLAQKIILGEVPEDMQEKRLMMLDMGSLVAGTKYRGEFEDRMK
                     KVIDEIYNDGQVILFIDELHTLIGAGGAEGAIDASNILKPALARGELQTIGATTLDEY
                     QKYIEKDSALERRFARIQVDEPTPEEAEVILQGLRTRYEEHHGVEITDEAVRAAVNLS
                     VRYITSRQLPDKAIDLIDESAAKVRLDQTDHLTKSTVIKLEIDELVQEKEAAIQKQDF
                     ENAAQLRRQEKALRKKLQKVSAIEAKQEQGYSDRVTEEDVATVVSEWTGVPLQQLEKK
                     ESERLLELEGLLHERVVGQDEAVKAVSRAIRRARSGLKDPDRPIGSFMFLGPTGVGKT
                     ELAKALSEVMFGSEDALIRVDMSEFMEKYSTSRLIGSPPGYVGYDEGGQLTEKIRQKP
                     YSVILLDEVEKAHPDVFNLLLQVLDDGHLTDSKGRKVDFRNTIMIMTSNIGATQIREE
                     KNVGFNVQDVTKDHKAMQKRILEELKKAFRPEFLNRIDETVVFHSLSKDEIHTIVQIM
                     SKAIIKRLKEQDIQVKITPSAIDVIGKAGFDPEYGARPIRRALQKEIEDRLSEALLGG
                     EIRLGDHVTVGASKGKITLNVRGPKKETVGSL"
     gene            complement(15086..15553)
                     /locus_tag="ACG8LA_002220"
     CDS             complement(15086..15553)
                     /locus_tag="ACG8LA_002220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HFQ0204501.1"
                     /translation="MAHQNTSDLIESYIKKILENSEMIEIRRIEMADLFNCVPSQINY
                     VINTRFTIQRGYLVESKRGGGGYIRIAKVRISDKKQLLEQINQLFDDTISEKNAFAII
                     QKLYEDQIITKKEGNLMLSAIAKNTLNFNEYEDHTRARILRAFLERLSYEDGK"
BASE COUNT         4567 a         3274 c         2793 g         5052 t
ORIGIN      
        1 gctttttatc ataaatacaa gaactacaat tcaatttgtc aaaaaacacg tagatttcct
       61 tctgagaaat ttatttacgt atcgaacctt tccctattca gtctttgcga tccaaaatca
      121 gttgggtaag ggaaaagaga ttctcttttg ttcgaagaga ggtggcaggt aatttcttta
      181 tttccttcaa agccttttct gtgtaagagg ccgctaactt cctagcttct tccacgcctc
      241 ctgtatgttc aacgattttg cgtacggcgt cgacatcttc ttctgtcatt gccgctttct
      301 tctctaaata aggtagtagc tttggtttgt ttttttgcaa agagtagatc aacggtaaag
      361 aatagacccc ttgacgcatg tcttctagta caggtttgcc gatttcctgg ctctcttttg
      421 tataatctaa aatatcatcg ataatctgaa aggccatccc gatagaaagt ccgatatctc
      481 ctgctttttt tgcgaagcgc tcgcttgttc cactttcaaa agcgccaaca gaacaactta
      541 attggaacag ttcagctgtc ttacctgaaa tattttccaa atattctttt acagaaagtt
      601 cataattata gcgatcatcc atctgcccta attcgccatt caatactttt tccatactgc
      661 gagaattcaa ttggagactt ttcaaggaag tggagtaatc agacaatagt ttaaaacagc
      721 agacaaataa atagtctcct gcatagacag aaacgacatt accaaactga ctacggatat
      781 taggctgacc acgtcgcaga tccgcttcat caacgatatc atcatggatc agtgtggccg
      841 tatggagcat ttcgatagaa gctgccaaag cgatggcttt gtctcgatct tgctctggtc
      901 caaattgtga gaacaatagc tgataggcag gacgcaacag ctttccgccg gcatggatcg
      961 tttctttgat tgcttgttcg acaggtttgt ttttcaggcg gacagtttct tccatccgtt
     1021 ttagtgtttc tgtcaattct ttacttaaag caggatagtt ttcccacatt ggatgtagct
     1081 tcataaaaaa actccttgtg tgacgattat tttttggtaa acattgggct ccatttttgt
     1141 ttggttccct gctcataatc tttttggaat cgttgaagtg tctgcacatg tcgtaaaaga
     1201 taattcgctg cgatcccgat tgcaatccct gataaaatcc ctaaaactga aaggactggc
     1261 aagtacaaca tgactgtcca tgattgtgca atgaaagaag ccatcaaaag ctgtccgaca
     1321 ttatgcatga aaccgccggc cgcactaatt ccgatgatac tgacacgttt tggtcctaat
     1381 tgcttgacca ataacattcc aaaataacta agcaaagcac cactcatact ataaaggaat
     1441 gtggaaatcg ttccgcctag caaagtagtc aggaatagtc gtagccaaag tagtaagaag
     1501 ctgtcttgtt ttttcatggt aaaaatggca acgatcgtga ttagattggc taagcctagt
     1561 tttgcaccag gcgcaaaaga aaaaggataa gggatcatat tttccaataa accaatgatc
     1621 actccttgtg caacaagtag cgaaatataa atcatttttt gtaatttact catggtgtgt
     1681 aaaggtctaa taaatcagac tgtcttcgtc acctccatct gttgaacgga cttcgatcac
     1741 taatttatgt ggcaaacaga cgatggtttc gccatttttc gttgcccagc ctcgacgtac
     1801 gcagatctgg tcatcgcaat ctgcttcttt tatccgtact cgatcgccat ctatctcgat
     1861 caagttataa tctccgtgtt catctttgta agtatatgtg ttgctctctt ctccagccat
     1921 caaagggaat gttttgattt ctgtgccatc cacacgcagt accgcttctt tttctgctgt
     1981 tgcggtgttt tgctgaagac caaaaatcat gactggtaaa aaagaaagaa cagtcaaaag
     2041 caaaataata aaaacatccc aaggtttgag cagacttttt tcagcaaatt ctttaaggct
     2101 catttttgtt ctcctttttc cagattaact cacccaattt tagcataaaa acaagaggtt
     2161 gtgacacctg tgtcttgctt tgagtaataa gaacgaagaa tagaaaacag ctttccatgt
     2221 tttctaattc tttgggctta ttaccgagaa gcagcaggtg gaacaccgtt tataacaaga
     2281 ggttgtgaca gaagtgggca acttcaagaa ataagaagga atttacgaaa attacttttc
     2341 aagtttttgt gaaatttcgg cttatttttc gaagaagcta cttctggaac accgtttata
     2401 acaagaggtt gtaacagagg ttgtgacacc tgtgtcttgc tcatggaggc ttatctcggg
     2461 catcttattc ctttaatttt acataaaaag gaggctgtga cggtttgtct cagccccttt
     2521 ctattgaaat cttgcattca aataacgttc tttatctatt tatttcttgc cgtactggga
     2581 acttggtcta ccgtaccacc aattacctag tgtacgttgt agccatggaa ttacccagcg
     2641 atccaaccca atcgcacgtc cggaaccgtt catcaatgcg aaagcaacaa aaatgaacca
     2701 aatgtttacc cagtaaaaca tgcctgataa gcagaacgtg atcaccaata caatcgttgt
     2761 cgcactgcat agccatgtga ataatccagc aatcaatgct aatgccaagg caatttcaaa
     2821 gaataccatg aatttttgga agaacattgc tacatcattg tttggcatga tcacttgcat
     2881 gatctttgtg aaccagtctg gtgacttctc aatcacagcc attggttctt caccgtatgc
     2941 ataactcaaa ccaaaatgtg cagcttgagt cgctgcttct ccggcacttg cccctgctcc
     3001 gctggcagct gtggttgcat caccagcagc agaagcacca ctggcaacat ctgttacatt
     3061 gtattcccat gtccaaggga acacactgtt tccagtgaac catgatcctt caccaaacca
     3121 agtacttggt ttgaacactt caccattccc aatgattttt ttggaagctt caacgaacca
     3181 aactaaacca tagaaaatac gaagtggcac actccataag acattgccgt aacgagaaga
     3241 atgtcctcga gtcacgttgc gatcatcttt gatatggaaa aactcatgca ttaaatattg
     3301 gaacatataa taaccagaac gaatatcaaa gaagtatttc aaattcacga tatgtttcat
     3361 tacgatagct aaaaatccgc ttaaatggat cttatcaaat aggttagcta ccccccattt
     3421 ggcaccaata gaaaccataa atccttgata gtttccttta aatttatgct tttctccgcc
     3481 tttgatcgaa gccacgatat tcgctgcggc tgtgtgtcct gtttgttcag cagcttgaac
     3541 gatctgcggt gtcggtgttc ctgggaattc ttcataaaag actaaatcac caatgatata
     3601 gatgttttta tcttcgtagc cttttgcctg catatattca ttggcgatca accgctgtcc
     3661 gcgtgctgat tctaatccaa agtcagcagc gtcagaagtt cctttgacac cagctgtcca
     3721 aatcagtgtg tgagtcggaa tgttgcgtcc gtctttcaat ttgatatgat cagcagccac
     3781 ttctacgatt ggtgcattca ataataattc cacgttgtgc ttacgcaaat agcgttcagc
     3841 ttttgcagca tcatttcgat ccaacatatt caagatcgtc ggcattgcct ctacgaccat
     3901 cagtgtgatt tcgtttggat ctaatttata atctttggct aggcgatttt tccagtcgat
     3961 cagttcccca atcatttcaa taccggtaaa tccagaacca cagacaacga aagtcagcat
     4021 ggctttacgc agttcatcat ctggttccaa tgcagctttt gctactgtct tctcaatatg
     4081 ttcccgaatc cttacagaat cttcaaatga ccaaagggtg aatccgtgtg ctttgacacc
     4141 aggtgtacca aagtcattcg gctctccgcc cattccaagg atcagctgat caaaaggata
     4201 ggaacctaat ttggtcttga cgatttttcg ttctttatcg ataccgatta cagtgtctgt
     4261 gacaagttgt acattctttt gacgagcaaa caaatgctgc agatcgtatt ggattgcttc
     4321 tggttctaca cgtccgccag ctacttcatg caactcggtc atcatagtat ggtacgaatg
     4381 acgatcgatc agagtaattg ctacatcttc ttttttcagt ttctttgcca agtattttgt
     4441 agctgaaaca ccggcatatc ctgctcctac aacgacaata ttttgctttg ccattgatca
     4501 tccgctcctt atagactatc tatataatga atatatgata attcttttag tttgatactt
     4561 attacacaat ctccatatat tatatagatg ttctgttctt ttgtctaact ccttttggat
     4621 ttttttcaaa ttttaaaata aagcgttttt tcacgaaatt tgctgaaaga aaacgtttga
     4681 aatattacat gggttattta tcaaaaatag ttgacttata ggctaaaaag attagaatgt
     4741 ataatgaatc acaaagaaaa attgtggact agaaatggaa tggtggggta ttaaaatgaa
     4801 gaaaaaacgt tttgtaactg gatttgccgt attagcattt tcagctctag tgttaggcgc
     4861 ttgcggcgca gatgacaacg gaagctcaaa ctcttcttct gaatcatcta cagcacaatc
     4921 ttcgactgca aaaagcacaa cagaatcatc tgcaaaagtt gtagctggcg gagatttgca
     4981 agacggcaca tataaattag aagaaaaaaa ttattcaaat ggttaccgtg cagtctttga
     5041 aatggttgta aaagacggca aaatcactga atcaaaatat gataacgtca atgaaaacgg
     5101 cgaatcaaaa acaaaagatg cagaatacaa caaaaacatg gaagcaaaat ctggcacaaa
     5161 cccagaaaaa tacattcctg agttgaatga ccaattctta aaagcacaaa gcgcaagcgg
     5221 tgtggaagtc gtaactggag ctactcactc atctgaaagc ttccaaaact acgcacaaca
     5281 attgatccaa gctgctcaag ctggtaacac agatacaatc gaaatcgaca atggtgctga
     5341 tttgaaagac ggcacttaca agcttgaaga aaagaactac tctaacggct accgtgtgca
     5401 attcgaaatg acagttgctg gcggcaaagt aactgaatca aactttgatt atatcgacaa
     5461 agacggtaaa tcaaaacaag atgatacaga atataatgaa aatatgaaag caaaaagcgg
     5521 tacagaacca aaaacttaca tccctactct gaacgacgaa ttcgtcaaag caatgggcga
     5581 agaagatggc tcacctgcta atgtagaagt tgttacaggt gctacacaca gctcacattc
     5641 attcatcatg tacgcacaac aattagtgaa tgcagctgaa aaaggcgaca ctcaaacaat
     5701 cgaagtagat aatatcgtaa cagaaaaata atcacataat catactaata aaagttggag
     5761 ggtgggacga tagccagatt aggcagtcgt ctcacctttc aaaatgaaga gaggaaaaag
     5821 atgcggaaaa aactactatt ttccttaatc acactgggca tctcttttat ggtgctaact
     5881 ggctgcagca actcagcaaa taaaacaacc actgaaagtt cagcagctac caagatattg
     5941 aaagatccat attctgatga acagttcttg ttagggactt acgttcgtat ccgtgtgtat
     6001 gatgaaggca aagaatcagc attgaaacct gccttcgatc gagtaaaaga acttggtgat
     6061 aaaatcacga tcaatcaaaa aggttctgag atcgatgaag tgaatgagca agctgggatc
     6121 aaaccagtaa aagtttctga tgacgtctac acgttagtca agcgggccta cgaatatagc
     6181 caagattctc aaggcggatt cgatatggcg attggtgcaa tcacacaatt atggcgaatc
     6241 ggttttgatg acgccagaaa accttcccaa gaagaaatcg atcaggcatt gaaattagtg
     6301 gattatcata agatcgaact aaatgacaaa gaaaaaactg tttatctaaa agaaaaagga
     6361 atgatcatcg atttaggtgc aatcgccaaa ggttacatta cggacgaagt agtgaaagtc
     6421 ttgaaaaaac aaggagtgac cactgccatc gttgacttgg gcggtaatgt ctatgtctta
     6481 ggccacagcc caagaggcga aaaccaagac tggacagtcg gcatccaaga tccgaacatg
     6541 gctcgcggat ctgttttagg ttctattaaa gaacggaaca aaacattagt tacctctgga
     6601 atttacgagc gttatttaga agtagatggc aaaaaatacc atcatttgtt tgatccaaaa
     6661 acgggttatc cgttcgacaa tgatatcgca agtgtcacga tcataacaga taaatcaatt
     6721 gatggtgacg ggttgtctac agcagtcttt tcaatgggtg tgaaaaaagg actggaatac
     6781 gtcgaaagcg aattgaataa cgggacggaa gcgatcttcg tgacaaaaga cgataaagta
     6841 tatgtgaccg atccaatcaa agacaccttc aaattatcgg aggactccca ttacacgatg
     6901 ggtgaccgtt ctgaactaaa ataaggagta cgaaccatga cactaaaaat ctttttagaa
     6961 gtagttgaaa tacgaacaaa ggtggctagt gtatttcctt ttgcggtagg ggtattattc
     7021 tctatcgctt tttttcatga gatacattgg ctaaacactt ttttattttt tattggaatg
     7081 ctagtttttg atttagcgac taccgctatc aataattaca tggattatga aaaggctcat
     7141 tctgaagtat ataagtatga agaaaatgtc attggccgca gaaatctatc tcctgtattg
     7201 attcgaaaca tgattttagc tatgattgca tttgtttttg ttatcggcgt tattctaacg
     7261 atcaatacgg gttggctttt acttttgatg ggatttatct gttgttttat tggagtattc
     7321 tatacattcg gaccgattcc tttatctcga atgcctttag gggaaatttt cagtggggtg
     7381 actatgggcc ttggaatttt tgccatggtc gtttatgtca atacattcgg ttcagatgtc
     7441 tatgatctga cagtcaactt ttcatctgga caatttgctt tggtaggaaa tctttgggct
     7501 atagcagcaa tcgtattagc ttccttaccc ttggtgttta cgattgccaa tatcatgttg
     7561 gctaataatt tgcgggatct tgaccgtgat attgaaaatc atcgctatac actagttttt
     7621 tatatcggac gtcctgcggg aacagtctta ttccagctat tgatgtatgc ttgctatttc
     7681 gtgattttaa tggggttgtt gagcggtatc tatgaatggc cgatcttggt caccttcttg
     7741 accttgccaa ttgtgaagaa gcatttggat caattcaagc aaacgttacc ccagcctatc
     7801 agtttcagct attccatcaa aaatatggtc ttattcaatg ccagttatgt attggggcta
     7861 ttactaacaa tcattatgca agccatttaa cagcatgaag aggttgtgaa aaaactgccc
     7921 tgcatcaagt aataagaaca gccaaataaa aatagctcct tatatttttc gtttggttgg
     7981 gcttattacc gcagatgcaa gcttttgaac accgtttatc aggaggttgt gaaaaagtcg
     8041 cttagtttcg agtattaaga aaaattttgt gaaaatggct ttccacattt ttgcataaat
     8101 ttggcttaat accgagaaac tggcttttga acaccgttta tcagaggttg taaaatcagt
     8161 gttttgtcct gagtattaga gaaacaaatg gaaaaatagt tcctcatatt ttgccgtttt
     8221 ttgagctaat accgaaggac agctgattga acactatttg ttcggaaaaa gtgactaact
     8281 atgacacaat ttttttcaca gtcccttttt tcacttgatt tgattcgtac cagcgaactt
     8341 gacgagaact ttcttggttt ggtaactata tggtattctt ttaacatcct cgtttgcttc
     8401 ttctaattta tttatacaaa gtcacacttt tttaaacatc tgttcttcga tacatttcta
     8461 tttcttttaa acatcgatac caatattttg aacttaagag tgcataccaa atggattcat
     8521 ttactcttcg tcagttacga agataatcaa aatctccaac ttccctactt atttcgtttt
     8581 gagaattatc gaagcaatct tacataaata actaaaaaac aaaaaaccag aaaatcagta
     8641 tactgatttt ctggttttac atggtttgtt caataaaaag ctgttggaac tgttaatatt
     8701 aaattatcgc atcgttacga attcttccgc tcctgttgga tggatggcta ctgtattgtc
     8761 aaagtcttct ttagttgcac ccatcttgat agccacggca aaaccttgca gcatctcatc
     8821 gacaccaaca ccaatagcat gtaagccgac gattctttct tcttttccga cacagatcaa
     8881 tttcatttcg catttttggc gataatcatt taatgcaaag tacattgggg taaagcgtga
     8941 acgataaact ttcaattcat tttcgccata tttttccaat gcttcttctt ctgtcaaacc
     9001 aattgttgca attggtggat gcgtaaagac gactgtcgga acaagtttat agtcaagata
     9061 agaatctttc tttccattaa ataaacgttc tgataaacgt ctaccagctg cgattgcaac
     9121 aggagtcaga tctaatttac cgatcacatc accaacagca aaaatatgtt catccgttgt
     9181 attttggtat ttatctactt tgataaaccc ttttttgtcc aattccacat ttgtattttc
     9241 cagacctaat ttttcggtat tcggtacacg tccaccggca aaaagtacac aatcaccagt
     9301 taaggtttca ccattttcaa atagcaccgt atattcgtca ttgtttttag taatttcttt
     9361 agcaatatga tgtgcgtaag tttttattcc agcttcttgg tacatttgga tcaaattgtc
     9421 cgaaagcatt ttatcaaacg ttctaagtgg tcgttctttt cgatatgccc acatgacttc
     9481 actacctaaa ccacgaaata cacctgaaag ttcagccgca atgtatccag cacctaaaac
     9541 gattgctctc ttaggtaact ctgttaattc aaaaaatcca tttgaatcaa ttgcgtattc
     9601 tccaccagga atggtcattt tacttgcacg gcctccagta gcgatcaaga ttttaggagc
     9661 acgataggtt tcaccgttta cttcgatcgt ttgactatcg ataaaagtag cgtaaccttt
     9721 tatagcctcg acatgattgc tatctaatcc tctttgataa gcaccgtgta gaaaatcaat
     9781 atatttttct cgtctttcta ctagaccggc gaaatcaaca ttttttaaat ctgcttggat
     9841 accgtaactt gaggcatctc gttcaattgt ttccaaaatc gtacttgctt gccacataac
     9901 ttttttaggt acacaaccga cgttgacaca tgttccgccc aattcattcg cttcaatcag
     9961 caaaactttt gcgccatgca tccctgctct gtttgctgaa gcaataccgc cagagccgcc
    10021 accaattacg atgtaatcat atatttgcat tttgttcctc cttattgaag agatcaatca
    10081 aaacctttat ttaacgatcc tttttctaca gaaaacaagt gtaacacttt tcttgaattt
    10141 tgtatgcgaa gatgcttaaa acagggatat atcagctttt tccttattta cgttttcgga
    10201 tcatatctcc aggtttcacc ggctgtgcga ctggcatagt taaaatcatc attggatttg
    10261 gtgctcggtc aatggattcg ccttcttcat tatgcataac ttcaacggtt tgactgaaat
    10321 gactgaatcc tggaccataa aattcgattt catctcctac agaaaacaag tttctctgac
    10381 gtatcgtagc aatctgtgtt gcctcatcat aagataatac ttcaccgaca aatttatata
    10441 ctgggatttt acgacgttca ccgaataatt gttcgttttc agttggtgta ttgtagtaaa
    10501 aacctgtagc taattctcgt tgtgctactt tccataactc gtcgatccat tcttgcttgc
    10561 agacatagtt ttcaggatct tccatataac tgtctacagc cgctttatag acatttgaca
    10621 ccgtagatac ataatggatc gatttcattc ttccttcgat cttgaagctg tctacgccgt
    10681 tttcaatcaa ttctggaata tgttcgatca ttgacatatc cactgcactc atcgagaatt
    10741 cttcttccac ttcgcctgta tcagttaaac tgtttcgttc ttgaccaaaa ggcatatcga
    10801 acaatccata cttccagcga caagattgag aacatccgcc acggtttgca tcccgcatcg
    10861 acatatggtt ggacaatgtg catcgaccag aataagagat acacatggca ccatggataa
    10921 atgcttcgat ttcggtatcc gtatttttac gaatctctgc cacttcctcc attgaaactt
    10981 cacgagctaa aacgacacgt tccaaccctt cttctttcca gaattccaat gtctcaaaat
    11041 tagttgctga agcttgagtg gataaatgga tcggcagacc tggggcttct gtcgcacaaa
    11101 tttcgatcaa agctggatca gaaacaatca ctgcagaaat accgacatca cgcaaactgc
    11161 ggaaaaattc ccctgctcca tcttcatttc cttcatgggt gaccatatta gcagcaacgt
    11221 ataccttcgc atcatgttct tttgcaaaag caactccttc agccatttct tcataagtaa
    11281 aattacctgc acggcttctt aaaccatatg cattcccgcc aatatatact gcatctgctc
    11341 cataatggat cgcggttttt aacttttcca gtgttcctgc tggcgctagg atttctggtc
    11401 gtttcaattt tctttttact gtcatttctt tcatcatact ccttatttga tagcagaagg
    11461 atcaatataa aagaatcctg tatctaattc acggttttca ggatgcaatt tactgatttc
    11521 gctagtcatt ttttccgctt tttcttgatc ccagctacct tctaaaattt gtttttttgc
    11581 ttcggcgaat agtcgagtga tgtttacgaa tttttcgcct ggagtaaata atccgtccaa
    11641 tttccatgta cagtaatgat gctgataaag ttcattcaat tcattcgaga gattcagatc
    11701 attgctggca aaaatatgtg tgccatgact atcttcataa atagaataat gtgtctcttc
    11761 ttttttaggt tccgagataa aaagacctct ttcacgatct ttttgttcgt cttgtttcgt
    11821 atagttatag taattctgta gcagtggacg tttggattga tggatgcatg tagcaccata
    11881 cacaagggtt tctacaggaa tatcgagttt ttcttccatc gccttcatct cttcaaaagg
    11941 aacttcacga gcaagtactg ctccaactgc gccttttttc gcccagaaat tgatttgacg
    12001 tgcgctcgtt actaatgttt cagcatcata aatatacggt atacgcaatt caggattttt
    12061 tttcatcgta taaataatac ctgtatcacc aactgtgatc acatctacgt ttatttcttt
    12121 taaaaaagcc aaatattcag gtacattttt cattttttca ggatgaatga tcccatttac
    12181 agcaatattc gcttttttac catacttgtg tgctaattct accaattgtc gctgttcttc
    12241 tcgtgtaaat gaagcaggca gacgcaatcc aaattgctct tcaccgaaat atagtgtatc
    12301 tgcacctgca gcaagcaact gttctgcttg ttcaatagtt tctactgtgg ttatgagttc
    12361 gatcataatt ttctcctcct acaacttcat aatagtagca tagctctaaa aactttccaa
    12421 tacttcttct atttaaagtc ggatttttga aaattatttc acaaaaaatc aaaataaagt
    12481 tcgatatatt ctgtccaaat ataaaaagag attgtgacaa aaatcttgtc acaacctctt
    12541 aatcaagtct tactattata aaaattcagc tacacaggcc aagtaactat agggaaccta
    12601 ctgtttcctt tttaggtccg cgaacattca atgtgatctt accttttgaa gcacctactg
    12661 ttacgtggtc acctaaacga atttctccgc caagcaaagc ctcgctcaat cgatcttcaa
    12721 tttctttttg aagtgcgcga cggattggac gtgcaccata ttcaggatca aatccagctt
    12781 tcccgatcac atcgattgca gatggtgtga ttttcacttg aatatcttgt tctttcaatc
    12841 gtttgataat cgctttgctc atgatttgga cgattgtatg gatttcatct ttactcaatg
    12901 aatggaagac gacagtctca tcgattcgat tcaagaattc aggtcggaaa gctttcttta
    12961 actcttctaa gatacgtttt tgcatggctt tgtgatcttt agtaacatct tggacattga
    13021 atccgacatt tttttcttct cgaatttgtg tcgctccgat atttgaagtc ataatcatga
    13081 ttgtatttct aaagtccact tttctacctt tagaatctgt taaatgacca tcatccaata
    13141 cttgcagaag taaattgaaa acgtctggat gtgctttctc cacttcatct aagagaatca
    13201 ctgaatatgg tttttgacga attttttctg tcaactgtcc accttcatca taccctacgt
    13261 atcctggagg agacccgatt aatcggcttg tactgtattt ttccataaat tctgacatat
    13321 caacacggat cagggcatct tcacttccaa acatgacttc tgaaagtgct ttggccaatt
    13381 ctgtttttcc gacaccagtt ggtccaagga acatgaatga accaattgga cgatcaggat
    13441 ctttcaatcc gcttcgtgca cggcggatcg cacgtgaaac tgctttgaca gcctcatctt
    13501 gaccaacgac acgttcatgc agaagtcctt ccagttctaa caagcgttcg ctttcttttt
    13561 tctccaactg ctgtagaggg acaccagtcc actccgatac aactgtagca acatcttctt
    13621 ctgttacacg atcagaataa ccttgctcct gttttgcttc aattgcagaa actttttgca
    13681 gctttttacg tagtgctttt tcttgtctgc gtaattgagc agcattttca aagtcttgtt
    13741 tttggatcgc tgcttccttt tcttgtacta gttcatcgat ttctagtttg atcacagttg
    13801 attttgttaa gtgatcggtt tgatccaaac ggactttcgc tgctgattca tcgatcaaat
    13861 caattgcttt atcgggtagt tgacgagaag tgatataacg aacagaaaga ttgactgctg
    13921 ctcgtacagc ttcatctgtg atctccactc catggtgctc ttcatatctt gtacgtaatc
    13981 cttgaagaat cacttctgct tcttcaggag ttggctcatc tacttgaatg cgagcaaaac
    14041 gtcgctctaa tgcagaatct ttttcgatat atttttgata ttcatctagg gtcgttgctc
    14101 cgatcgtttg taattctcct cgagctaacg ccggtttcaa gatattcgaa gcatcaattg
    14161 ctccttctgc tccacctgca ccaattaagg tatgcaattc atcaatgaat aagattactt
    14221 gaccatcatt atagatttcg tcgatgacct ttttcattcg atcttcaaat tcaccgcgat
    14281 atttcgtacc agcaaccaaa gatcccatat caagcatcat caggcgcttt tcttgcatgt
    14341 cttctggcac ttcacctaaa atgatttttt gagctaaccc ttcagcaatg gctgttttgc
    14401 ctacaccagg ttcacccacc agtacagggt tattctttgt ccgtcggcta agaatctgga
    14461 taagccgttt cacttctctc gaacgaccaa caactgggtc cagcttgttt tcttttgcta
    14521 atttcgtcaa atcacgtgct aatgaatcta gcgtaggtgt tccttgcggt gtttgccgtt
    14581 tatcttgtac atttacattt ctacgacgat tcattccttt tccagcagaa tcaccagcta
    14641 gccccatttt ttgtttcaga acttgacggg cttttgaaag gctgatacct aagttgatca
    14701 tgattcgagt agccatgata ctttcatctt ttaataagct catcaaaata tgttctgttc
    14761 caactttttg agaaccagtt ttcttcactt cgctgctagc taaagcaaaa acttgtttca
    14821 ttcttggtga atatggaaga aagactcctt tagggtaaga acggatacca ccataaccaa
    14881 tcagatgttc aatttcttca taaatttccg tttcattcaa atccatttca cgtaatactt
    14941 ttccagcaat tccattttgc tcgaccacta aggctagtaa aacatgttct gaactaactg
    15001 attgatgttt caaccgtttt gcttcttctt gtgcaatttc taatactgct tgggctcttt
    15061 cagtaaaaag ttcttccatc taatctcact tcccatcttc ataacttaaa cgttccagaa
    15121 atgctcggag aatccgagca cgtgtatgat cttcatattc attgaaattc aatgtgtttt
    15181 ttgcaattgc actcaacatc aagtttcctt ctttttttgt aattatttgg tcttcataaa
    15241 gtttttgaat aatagcaaaa gcatttttct cactgattgt atcatcaaat aactgattta
    15301 tctgctcaag taattgtttt ttatctgaaa tccttacttt tgcaattcgt atataaccac
    15361 caccaccacg tttgctttct actagataac cacgttggat ggtaaaacgg gtattaatca
    15421 catagttgat ttgtgaagga acacagttaa agaggtctgc catttcaatc cttcgaatct
    15481 cgatcatttc actattttcc agaattttct ttatatatga ttcaattaaa tccgaggtat
    15541 tctgatgtgc catcttattc attccctttg actaatattg accttaatta taacgaattt
    15601 gataatagaa agaaagaaga acgctttttg ttaaataaat cctttagaat caacaaaaaa
    15661 aaatacggaa tatactattc cgtatc
//
LOCUS       DAZKKZ010000062        15138 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.064, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000062 DAZKKZ010000000
VERSION     DAZKKZ010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15138)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15138)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15138
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.064"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            5..2377
                     /locus_tag="ACG8LA_002221"
     CDS             5..2377
                     /locus_tag="ACG8LA_002221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArdC-like ssDNA-binding domain-containing
                     protein"
                     /protein_id="HFQ0204502.1"
                     /translation="MAEEKEPLDNSRLGKSKRKLVRLQNELNEQIEKMFEHQKMTNGQ
                     PMNDKRNGRSWFNQQERIENKVQSLREEIKQQEEYVEKLERQEELKEMGYNKYGGLDM
                     TIDNIPRIKEEIERFEKGESAFSAATIRKYQRKLETLEQLKEKSEKGKENILPEVQAI
                     IDSGRVTQWKKNPTIYFLKGYRKVALELNENGGFEESKKYQATSEEEKAAVRELLEEA
                     RPTDSMKEKENDHFYRVEFNENDPEKGLKSYGGEIVTFELIDQLKTLDNQYAAEAGYY
                     KFYFEEVKNGEVVDQIRMDLGDGVNSNQPIYLELAKLCEQVPEKEQKQSVKNEPVSKE
                     QMQSKETKTKQKGYQKRTAEEIKQEVKSLSQQALDAVKKHTHSPEDVKELLNFMSRFP
                     ERSFRNQLLIEEQFPGATACLGRAALKKEGIYIKKGEQGNKIFVRKTVKGFYEKGRGF
                     VRETEATPEDKKRIESGQIEVIKKPYYTIEKVFDITQTQLKPEDYPKIFPNRVFDFQL
                     DKKGQSELQAGIQAVANNIGIQIRDMTESEVYQRELGQARGAYVRNEFTGEEEIVMNT
                     RNTPTQHLATSIHELAHARMHKFSELDTATKELQAEMTSYIVCKHFGMDTSEKAIPYI
                     AAWTKNGQTLDDKEAAERGKIMNDVSRVANEFIQTISNEINQYREREPEIQPAEVKQE
                     HKNTLETPENKNIVPVGSLWIDKKDGKVMEEDTGRTLHLKDAAFIEDPQHNQVILKGK
                     SYGKEIQTALPSEEFALGNPFRFSLETVSEVAKRKNEIYYEQQLSQKERV"
     gene            2438..3898
                     /locus_tag="ACG8LA_002222"
     CDS             2438..3898
                     /locus_tag="ACG8LA_002222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014401506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HFQ0204503.1"
                     /translation="MTEKKMSLIDRCKQIDIVDFARNNGMAVVNKGRDYRLEDHDSFV
                     FDRRKQRFYWNSQNISGDIIELAKLFFIDKEIQDPKQQFKAATDFILKNEDKTERVEN
                     LHFETEKYKDHPVDYQPLTEKGRNYLKEERKLPEWLIDYAEKEGLIAELKPKYERQNF
                     LVRDDRLDHAVAFLWKDPQTKETVGASYQGTFIDYERFGERGTYKHIDKNSTANHGFN
                     LKIGDPKQIKFFESSIDLLSYAALNRDQLNDTWLVSMEGLKHHVISHYFGEAVSELRK
                     KQAFPQSIEICVDNDRAGHIFYEKEQLMGAVDPFTNQKVRCERGIANDWQVPKEYKII
                     YEEVAKEEKVTPEAIMAIHKTENNLQLTNQLVSAHKVNAFFGQQLSVNDSIEAINLKD
                     ICREVAKELKVCERVDGTYDFDRFYQEKGDINAQILFSYKAEQYYKGYKNHEHEFVPE
                     VKKDWNDQLKHEIQQQEIRKQKRAMLFQQGRQQERE"
     gene            3909..6113
                     /gene="topB"
                     /locus_tag="ACG8LA_002223"
     CDS             3909..6113
                     /gene="topB"
                     /locus_tag="ACG8LA_002223"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HFQ0204504.1"
                     /translation="MKTVILAEKPSQAKAYADSFSKATRKDGYFEIQDRLFPGETVIT
                     YGFGHLVELDSPDMYDENWKQWSLEHLPIFPTHYHYHVPKDKKKQFKVVKQQLQSADT
                     IIIATDSDREGELIAWTIIQQVGADQGKTFKRLWINSLEKEAIYQGFQQLRDAKETYP
                     KFEEAQARQIADWLIGMNGSPLYSLLLQQKGIPGSFSLGRVQTPTLYMIYQLQEKIRN
                     FKKEPYFEGKSEVIAQNGAFDAKLDPNETQATQEAFEDYLKEKGVQLGKQPGMIRQVE
                     TEKKSAASPRLFSLSSLQSKMNQLMKASAKDTLEAMQGLYEGKYLSYPRTDTPYITEG
                     EYAYLLDHLDEYKHFLRAEEISTPIHTPNSRYVNNKKVQEHYAIIPTKTVMTEATYES
                     LTPLQQAIYEQVLKTTVAMFAEKYTYEETTILTQVQQLQLKAIGKVPIDLGWKKLFGK
                     ESDGKEKEEEPLLPKVTKGEMVTVDLQVLEKETKPPQPYTEGTLITAMKTAGKTVDSE
                     EAQSILKEVEGIGTEATRANIIETLKQKEYIKVEKNKLVVTNKGVLLCQAVEKEPLLT
                     SAEMTAKWESYLLKIGERKGTQTTFLANIQKFVSHLLEVVPGQIQSIDFGSTLQEVKA
                     ASEKQEAARHLGICPKCQEQEVLLYQKVAACTSEACDFKLWTTIAKKKLTATQLKEII
                     QNSRTSQPVKGLKGQKGSFEATIVLKEDFTTGFEFSEKKKTNFKKRTRRTTK"
     gene            6129..6278
                     /locus_tag="ACG8LA_002224"
     CDS             6129..6278
                     /locus_tag="ACG8LA_002224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204505.1"
                     /translation="MRNTTHKQQEIENQKAKIRSEQEKLRASKRRLQQLKNQQRIQKE
                     IELDR"
     gene            6353..6946
                     /locus_tag="ACG8LA_002225"
     CDS             6353..6946
                     /locus_tag="ACG8LA_002225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HFQ0204506.1"
                     /translation="MQEKLKELLAIRDGNLSMKEARKLGIAATTVQRLVNQGKLIKVD
                     RGYYVEDGHGIDDLFWLQQRFSRGIFSHETTLDIYQLSTNMPKFIHLTFPHGYNVDRS
                     ITKEQQLQFHFVKKEVYELGKVEGTSFQGNPITMYDKERTLCDIWNPRYEIEYEMKLE
                     ALKEYMEDPLRDPSKLRDYMTKLHVEKEMKYHMQSLY"
     gene            6959..7858
                     /locus_tag="ACG8LA_002226"
     CDS             6959..7858
                     /locus_tag="ACG8LA_002226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HFQ0204507.1"
                     /translation="MTPTQFAAKTRNLAKRTGLNAQLVQRHFMMDRLIEQISESKYKN
                     DFILKGGFLLGSKYGIDRRTTIDIDTTFRNSKLTEEKLKSIFNDLTRKPTKEGIVFSI
                     QGMKETREADFYPGFQIKLVANLEKVRVPFKMDVTTGDSIYPEVDTHYHQLMFEDKKV
                     EIPAYPTAQIIAEKLSATFSFGTDNSRAKDYYDLFTIPKLENIDTKELYKSVRNTFTK
                     RGDTKPLSFYYEREMDKIIGNDYLEKQWEKYRSVNTFANSISFTDTVNEIDHLMKSVI
                     KIENQERKRQFKRSQQMNQEMER"
     gene            7861..8358
                     /gene="ssb"
                     /locus_tag="ACG8LA_002227"
     CDS             7861..8358
                     /gene="ssb"
                     /locus_tag="ACG8LA_002227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HFQ0204508.1"
                     /translation="MINNVTLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQNGNR
                     EADFINCVIWRKPAETMVTLAKKGSLIGVVGRIQTRTYDNQQGQRVYVTEVVADNFQL
                     LESKAATESRAHADQSSTSPSTTTFEQRDTATPNNNGLNALQNPFGNPFGGQSIDISD
                     DDLPF"
     gene            8724..8984
                     /locus_tag="ACG8LA_002228"
     CDS             8724..8984
                     /locus_tag="ACG8LA_002228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204509.1"
                     /translation="MNKYVGLLDKIRVIKTQPLLVRFTLQTIHESINCVVADIEIIDK
                     LLIMDDGKYNIAVTGHFNKRNQLVIASMYVRNPDHFTRSMGI"
     gene            9429..9635
                     /locus_tag="ACG8LA_002229"
     CDS             9429..9635
                     /locus_tag="ACG8LA_002229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrA"
                     /protein_id="HFQ0204510.1"
                     /translation="MRKKFDYWGVPFSELFPNYHAPHTVECDCGQRAKCIKSYRLYQC
                     PTCGKKYTLSYGDYILIDEKGKKR"
     gene            9656..9886
                     /locus_tag="ACG8LA_002230"
     CDS             9656..9886
                     /locus_tag="ACG8LA_002230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204511.1"
                     /translation="MTVKEVVQILVDKEVISEKVAEALLIPRYWTIETPLVEDAPTML
                     FEDLVKIAGYELHYQENMETYENEYWLTKLEN"
     gene            9902..10339
                     /locus_tag="ACG8LA_002231"
     CDS             9902..10339
                     /locus_tag="ACG8LA_002231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204512.1"
                     /translation="MAQNYYDEFVKLPLDKMAQKMEDMTFLYHETRVPKKHYKERLSV
                     AVEEMIESGVEMNLIATYYRTLEELKKQNAKWFFQALLCLEVGVKPSTIKPSEYQALE
                     LTYGKFVETKKAKTVSSEWLDYFENINKYGAYYTMKKEDNENE"
     gene            10332..11039
                     /locus_tag="ACG8LA_002232"
     CDS             10332..11039
                     /locus_tag="ACG8LA_002232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204513.1"
                     /translation="MNKVIYQLTTEDVSHFLTNKEHLNEVIRRIQKDFSCMEEMKYFI
                     QRVEEQLYLESETSQTKVTVSNNYLDVYKHRPETVKKGTELLRLETEKYIMNVYLERS
                     ELVENFVSCTICRKHYYSESEYYSIFESMELMEEEMEELNSKNATIDDYYLVFTRFLT
                     CGTESIVLMGMDYELAVPEAFLREYVEEVDNPGDDWYTTLTDFLDTYTYDDTEEIQNE
                     LDRKRMPYQRFERKKRQ"
     gene            11203..11403
                     /locus_tag="ACG8LA_002233"
     CDS             11203..11403
                     /locus_tag="ACG8LA_002233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204514.1"
                     /translation="MNKIIPLLFVLCIGEILMRHGAAVHLNFVVFLGILVFCLIFWRF
                     VLALVSLLFKLIAAIFFIGLFR"
     gene            11419..11598
                     /locus_tag="ACG8LA_002234"
     CDS             11419..11598
                     /locus_tag="ACG8LA_002234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204515.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQQLKQKYGKSESKIMCIALDLL
                     IAQEKAGFDIPALKK"
     gene            11923..12186
                     /locus_tag="ACG8LA_002235"
     CDS             11923..12186
                     /locus_tag="ACG8LA_002235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PbsX family transcriptional regulator"
                     /protein_id="HFQ0204516.1"
                     /translation="MEMLPIKKWGNSNGLRLPKYIMEYLGIHTEDKVKIIQEEVNGQK
                     RLIIEAANIENELTIEQLFENYTDERNHVTIQNLGEAVGNEKW"
     gene            12180..12530
                     /locus_tag="ACG8LA_002236"
     CDS             12180..12530
                     /locus_tag="ACG8LA_002236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016610020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HFQ0204517.1"
                     /translation="MVRKPRQGDILLLNTAPRSGHEQTGKRPYIVLSHDIIADYSNVV
                     TVAPISSTTRNYPLYVNINSEYEMKTTGKVLLDQLTTIDYEARECIFLEKAHDSLVEE
                     LLMKVRTVFQKVSK"
     gene            complement(12554..13168)
                     /locus_tag="ACG8LA_002237"
     CDS             complement(12554..13168)
                     /locus_tag="ACG8LA_002237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFQ0204518.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAERIFIEKQSGATITHRP
                     VFQEALDFVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVQLIITSLPIMAEAIGN
                     PLLDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSANAKDPQ
                     RRLVYKNIVEDLKKGVAIAKIAKDYNVTRQTVYRIKKDSMVNHE"
     gene            13482..13904
                     /locus_tag="ACG8LA_002238"
     CDS             13482..13904
                     /locus_tag="ACG8LA_002238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204519.1"
                     /translation="MKNKFILSLGILTIGVSVTGTTIPTFADSTNEPTTVVDNNQELT
                     PLDRNGIAIGNPTNDLTVTENYLIVSPLLARAASKTIRVTGTMIFDKVGWPSRPPQSR
                     NWKEKRNGYWYYGKLYLQSYKSAGNNWIATYSGTLTRK"
     gene            13914..14117
                     /locus_tag="ACG8LA_002239"
     CDS             13914..14117
                     /locus_tag="ACG8LA_002239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204520.1"
                     /translation="MPEFVNTPNFYQDSDILSKINLPKEESALQVQRTLQETQKIQKS
                     ISNLEDSEEKRKKRDQKTYQKEK"
     gene            14328..14912
                     /locus_tag="ACG8LA_002240"
     CDS             14328..14912
                     /locus_tag="ACG8LA_002240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFQ0204521.1"
                     /translation="MKIGYARVSTGLQNLDLQEDSLNKFGCEKIFTDHMSGAKSNRPG
                     LEMAIDFVRSGDTLVVWRLDRLGRNMEDLISIVNRLNERGVSFHSIQENITMDKSSST
                     GQLMFHLFAAFAEFERNLILERSAAGRAAARARGRFGGRPEKLSEQDLELLKTLVDSG
                     TPIKTIAERWNVSRTTIYRYLAKMEEKNGKTNSH"
BASE COUNT         5569 a         2451 c         3062 g         4056 t
ORIGIN      
        1 gaacatggca gaagaaaaag aaccactaga caatagtcgt ttgggaaaat ccaaaagaaa
       61 actagtacga ttgcaaaatg aattaaacga acaaattgaa aagatgtttg aacaccaaaa
      121 aatgacgaac ggtcaaccaa tgaacgacaa gaggaatggc cgttcatggt ttaaccagca
      181 agaacgaatc gaaaataaag tccaaagtct gagagaagag atcaagcaac aagaagaata
      241 cgtggaaaag cttgaaagac aagaagagct aaaggaaatg ggctataaca agtacggcgg
      301 actggatatg acgatcgata atattccaag aatcaaagaa gaaatcgaac gctttgaaaa
      361 aggtgaatcg gctttttcag ccgccacgat ccgaaaatac caacggaagt tggaaacatt
      421 agaacagctg aaagaaaaat cagaaaaagg aaaagaaaat atcctccctg aagtacaagc
      481 gatcattgac agcggacgag tgacgcaatg gaaaaaaaat ccaaccattt attttttgaa
      541 aggctatcga aaagttgctt tagaactgaa tgaaaacggg ggatttgagg aatcaaaaaa
      601 ataccaagcc acgtcggaag aggaaaaagc agctgttcgt gaattacttg aagaggctag
      661 accaactgat tctatgaagg agaaagaaaa cgatcatttc tatcgagtag aattcaacga
      721 aaatgatcca gaaaaaggat tgaaaagtta tggtggggag atcgtaacat tcgaattgat
      781 cgatcaactc aaaacattgg ataaccaata cgccgcagaa gcaggttatt ataaattcta
      841 ttttgaggaa gtgaagaacg gagaagtagt cgatcagatc cgaatggatc taggggatgg
      901 cgtcaacagt aatcaaccaa tctatttaga gttagcaaaa ttgtgcgaac aagtacctga
      961 gaaggaacaa aaacaatcgg tcaaaaatga acctgtttcg aaagaacaaa tgcagtcgaa
     1021 agaaacaaaa acaaaacaaa agggctatca aaaacgaacg gcagaagaga ttaaacaaga
     1081 agttaaatcc ctttcgcaac aggcactgga tgcggtgaaa aagcataccc attctcctga
     1141 agacgtcaaa gaacttttga actttatgtc tcgttttcca gaacgatcct ttagaaatca
     1201 attattgatt gaggaacaat ttccaggtgc aacggcttgt ttaggtcgtg ccgcgttgaa
     1261 aaaagaagga atctatatca aaaaagggga acaagggaac aagatctttg tcagaaaaac
     1321 ggtcaaaggg ttttatgaga aaggacgtgg ctttgttcga gaaacagaag ctacaccaga
     1381 agataaaaaa cgaatcgaaa gtggtcaaat cgaagtgatc aaaaaacctt actatacgat
     1441 tgaaaaagtg tttgatatca cacaaacaca gttaaaacct gaagactatc cgaaaatctt
     1501 tccgaaccgt gtctttgatt ttcaattgga taaaaaagga cagtcagaac ttcaagctgg
     1561 gattcaagcg gtagccaaca atattggaat acaaattcga gatatgacag aaagtgaagt
     1621 ctatcaaaga gaattaggac aagcacgtgg ggcgtatgtt cgtaacgaat ttactggcga
     1681 agaagaaatc gtcatgaata ctcgaaatac tcctacgcag catttagcta caagtattca
     1741 tgaattagcc catgcaagaa tgcacaaatt ttcagaatta gataccgcaa ctaaagaatt
     1801 gcaggcagaa atgacttctt atattgtgtg caaacatttt ggaatggaca cgtcggagaa
     1861 agctattcct tatattgcag catggacgaa gaatggtcag acgttggatg ataaggaagc
     1921 tgcggaacgt gggaaaatca tgaatgatgt cagccgtgtc gcaaatgaat tcattcaaac
     1981 catttctaat gaaatcaatc aatacagaga aagagaacca gagatccaac cagcagaagt
     2041 gaagcaggag cataaaaata ctttagaaac gccagagaat aagaatattg tgcccgttgg
     2101 ttcactttgg atcgacaaga aagacgggaa agtaatggaa gaagatacgg gtcgaacgtt
     2161 acatttgaag gatgcggcgt ttattgaaga tccgcagcat aatcaagtaa ttttaaaagg
     2221 aaaaagttat ggaaaagaga tccaaacggc gttaccttca gaagaatttg cgctaggaaa
     2281 tccattccga ttttcacttg agacagtgtc agaagtggca aaacgaaaaa atgaaatcta
     2341 ttatgaacaa caattgtcac aaaaagaacg tgtataaaac aagtaaaaaa gactatctga
     2401 aaaacggata gtcttttttc ttttgggagg ttttaaaatg accgagaaaa aaatgagtct
     2461 tattgatcga tgtaaacaga tcgatatagt ggattttgct cgaaacaatg gaatggctgt
     2521 agtcaataaa ggacgagatt atcgcttaga agaccatgat tcatttgttt ttgatcgaag
     2581 aaaacaacgt ttttattgga acagtcaaaa tattagtggc gacattattg aattagctaa
     2641 actttttttc atagacaaag agatccaaga ccctaagcaa caatttaaag cagccactga
     2701 ttttattcta aagaatgaag acaaaacaga acgagtggaa aatcttcatt ttgaaacaga
     2761 aaagtacaaa gatcaccccg ttgattatca accactcaca gaaaaaggaa ggaattatct
     2821 gaaggaagaa cgaaaactac cagagtggct gattgattat gcagaaaaag aagggttgat
     2881 tgccgaacta aagccaaaat atgaacggca aaatttctta gttcgagacg atcgtttaga
     2941 tcatgcggtc gcctttttat ggaaagatcc acagacaaaa gagacagtag gggcgagtta
     3001 tcaaggaacg ttcattgatt atgaacgttt tggtgagaga ggcacatata agcatataga
     3061 taaaaattcg acagcgaatc atggctttaa cctaaagatc ggtgacccta agcagataaa
     3121 attttttgag agtagtattg atttacttag ctatgctgca ctgaatcgtg atcagttaaa
     3181 cgatacgtgg ttagtctcta tggaagggtt aaaacaccat gtgatcagtc attattttgg
     3241 tgaggcagta tctgaattga gaaagaaaca agcctttcct caatccatcg agatttgtgt
     3301 ggataatgac cgtgcaggac atattttcta cgaaaaagaa caattaatgg gcgcagtcga
     3361 tccatttacg aatcagaaag tacgttgtga acgaggaatc gctaatgatt ggcaagtgcc
     3421 aaaagaatac aaaatcattt atgaagaagt cgcaaaagaa gaaaaggtca caccagaagc
     3481 tattatggcc atacacaaga cagaaaacaa tctgcaatta acgaaccaac tggtttccgc
     3541 tcacaaagta aatgcgtttt ttggccagca gctttctgtt aacgattcaa tagaagccat
     3601 taatttgaaa gatatttgta gagaagtcgc aaaagaatta aaagtttgtg aacgcgtgga
     3661 tggtacgtac gattttgatc gtttttatca agaaaaaggg gatattaatg cgcagattct
     3721 tttctcttat aaagcagaac aatactacaa aggctataaa aatcatgaac atgaatttgt
     3781 acctgaagta aaaaaggact ggaacgatca attgaagcat gagatccagc aacaagaaat
     3841 cagaaagcaa aaacgtgcca tgttgtttca acaaggcaga caacaagaaa gggagtgaaa
     3901 tcgtcatgat gaaaaccgtt attttagcag aaaagccgtc acaagcgaaa gcttatgccg
     3961 atagcttctc taaagccact cgaaaagacg ggtattttga aatccaagat cgattgtttc
     4021 ctggtgaaac tgtgatcacg tatggttttg gtcatttagt cgaattagat tcgcccgata
     4081 tgtacgatga aaattggaaa caatggtcat tagaacattt gcctattttc cctacacatt
     4141 atcactatca tgttcctaaa gataagaaaa agcaattcaa ggtggtgaaa cagcaacttc
     4201 aatcggccga caccattatt attgcgacag atagcgatcg tgaaggggaa ctgatcgctt
     4261 ggacgatcat tcaacaagta ggcgccgatc aaggaaaaac ctttaaaaga ctttggatca
     4321 actccttaga aaaagaagcc atttatcagg gattccagca gttacgagac gcaaaagaga
     4381 cctatccaaa atttgaagaa gcacaagcac gtcagatcgc cgattggtta attgggatga
     4441 acggtagccc actgtatagt ttactcttgc agcaaaaagg cataccagga agcttttcct
     4501 taggcagagt ccaaacccca acgctttaca tgatttatca attgcaggaa aagattagaa
     4561 atttcaagaa agaaccttat tttgaaggaa aatccgaagt aatcgctcaa aatggcgcat
     4621 ttgatgcgaa gcttgatccg aatgaaaccc aagcgacgca agaagcattt gaagattatt
     4681 taaaagaaaa gggggttcaa ttgggaaaac agccaggcat gattcgccaa gttgaaaccg
     4741 agaaaaaaag cgcggcaagt ccacgtcttt tttctctatc cagccttcag tctaaaatga
     4801 atcagctcat gaaagctagt gccaaagaca ctttggaagc catgcaaggc ttgtatgaag
     4861 ggaaatatct aagctatccg cgaacggata ccccttacat tacggaaggg gaatatgcgt
     4921 atctgttgga tcacttagac gaatacaagc attttttgag ggctgaagaa atttcgactc
     4981 ctattcatac accgaatagt aggtacgtga acaacaagaa agtccaggaa cattacgcaa
     5041 tcattcctac aaaaacagtt atgacagaag cgacgtatga aagtctgaca cctttacaac
     5101 aagcgattta cgagcaagtt ttaaaaacga cagtggcgat gtttgcggaa aaatatacct
     5161 atgaagaaac aacgatcttg acgcaagtcc agcagcttca gttaaaggca atcggaaaag
     5221 taccgataga tctaggttgg aagaagttat ttggcaaaga gagcgacgga aaagagaagg
     5281 aagaagagcc gctacttcct aaagtgacaa aaggagaaat ggtgacggta gatctacaag
     5341 tccttgaaaa agaaaccaag ccaccacaac cttataccga aggtacgttg atcactgcga
     5401 tgaaaacagc tgggaaaacc gtggatagtg aagaagcgca atccatattg aaagaagtgg
     5461 aaggaatcgg tacagaagcg acacgggcga atattattga aaccttgaaa caaaaggaat
     5521 atatcaaggt agagaaaaat aagcttgtgg tgacgaataa aggggttttg ctttgccaag
     5581 ctgtggaaaa agagccgctg cttacgagtg ccgaaatgac cgccaaatgg gaaagctact
     5641 tgttaaagat tggagaacga aaaggaacac aaaccacttt tctagccaat atccaaaagt
     5701 ttgtctctca cttattggaa gtcgtcccag gacaaatcca atccattgat tttggatcga
     5761 cgttacaaga agtgaaagca gccagtgaaa agcaagaagc cgcgcgtcat ttaggaattt
     5821 gtccaaaatg ccaggaacaa gaagtcttac tctatcaaaa ggtggcagct tgtacgtctg
     5881 aagcctgtga ttttaaatta tggacaacga ttgccaaaaa gaaactcaca gcgacacagc
     5941 tgaaggagat tattcaaaat agccgaacaa gccaaccagt gaaagggtta aaaggtcaga
     6001 agggttcgtt tgaagcaacg attgttttaa aagaagactt cactacaggc tttgaatttt
     6061 ctgaaaagaa aaaaacgaac ttcaagaaaa gaacacgacg cacgacaaaa taatggaggg
     6121 ttaatcttat gcgtaataca acacacaaac aacaagaaat cgaaaatcaa aaagccaaaa
     6181 ttcgttcaga acaagagaaa ttacgtgcca gtaaaagaag acttcagcaa ttaaagaacc
     6241 agcaacggat tcaaaaagaa atcgaattag atcgatagac attaaccttg ttacaaatac
     6301 actatcatga tatatttaat gtagtgtatt tgtaacaaaa ggggggaagt aaatgcaaga
     6361 gaaactgaaa gaattgttgg ctattcgcga tggaaattta tctatgaagg aagccagaaa
     6421 attaggaatc gcagcaacca ctgtacaaag attggtgaat caaggaaaat tgatcaaagt
     6481 tgatcgtggt tattatgtag aggatggtca tggaatagat gatttatttt ggcttcagca
     6541 acgtttttcc aggggaatct tctctcatga aacgacttta gatatttacc agctttctac
     6601 gaatatgccg aaattcattc acttaacttt tccccatgga tataacgttg atcgttcaat
     6661 tacaaaagag cagcagttac aatttcattt cgtgaagaaa gaagtttatg aactaggaaa
     6721 agtagaggga acttcctttc aaggaaatcc tattactatg tatgataaag agcgtacact
     6781 ttgtgatatt tggaatccga gatatgaaat tgaatatgaa atgaaattag aagcattaaa
     6841 agagtacatg gaagacccat tgagagatcc aagtaaatta agagattaca tgacaaaact
     6901 acatgtagaa aaagaaatga aataccacat gcaaagctta tattgatgga ggaaaaagat
     6961 gacaccgaca caatttgcag caaaaacaag aaatttagca aagaggacag gattaaatgc
     7021 acagttagta caacggcatt ttatgatgga tcgtttaatt gaacaaattt ctgaatctaa
     7081 gtataaaaat gatttcattt tgaaaggtgg ctttttatta ggatcaaaat atggaatcga
     7141 tagaaggacg acaattgata tcgacacgac atttagaaat agcaaattaa ctgaagaaaa
     7201 attgaagagt atttttaatg atttaactag gaaacccacg aaagaaggta ttgttttctc
     7261 tattcaagga atgaaggaaa caagagaagc cgatttttat cctggatttc aaattaaatt
     7321 ggtggctaat ttagagaaag tacgtgtgcc atttaaaatg gacgtgacaa caggagattc
     7381 tatttatcct gaagtagata cacactatca ccaattaatg tttgaagata aaaaggtgga
     7441 gattccagct tatccaacag cacaaattat tgcagaaaag ctaagtgcta cgttcagctt
     7501 tggcacagat aattcgagag caaaagatta ctacgactta tttaccattc cgaaactaga
     7561 aaatatcgat acgaaagagt tatacaaaag tgttcgaaat acatttacaa aacgtgggga
     7621 tacaaaaccg ttgtcctttt attatgaaag agaaatggat aagatcatag gaaatgacta
     7681 tttggaaaag cagtgggaaa aatatcgctc agttaacacg tttgcgaatt ccatttcatt
     7741 tacagataca gtcaacgaaa ttgatcacct aatgaaaagt gtgatcaaaa ttgaaaatca
     7801 agaaagaaaa cggcagttta aaagatcaca acaaatgaat caagaaatgg agagataaag
     7861 atgatcaata atgtaacttt agtaggacgc ttaaccaaag atccagattt acgttatacc
     7921 gcgagtggta ctgcagtagc gacttttacc ctagctgtca accgaaattt cacgaatcaa
     7981 aacggcaatc gagaagctga ttttattaac tgtgtgattt ggcgcaaacc agcagaaaca
     8041 atggtgacat tagctaaaaa aggtagcttg attggtgtag ttgggcggat tcaaacgcgg
     8101 acttatgaca accagcaagg acaacgtgtg tatgtgacag aagttgtggc cgataatttc
     8161 caactattag aaagcaaagc agcgacagaa agccgtgcgc acgctgatca atcgtccacc
     8221 agtccaagca ccaccacttt tgaacaacgg gatacagcga cgcctaataa caatggattg
     8281 aacgctttac agaatccatt tgggaatcca tttggtggac aatcaatcga tattagcgat
     8341 gatgatctac cgttctaagt agcattttct attggttgca tttgctacgg tttatgttat
     8401 aatttagtca acaaaaagaa ttttcaatct ataaccaaaa accactagct ggcgggctag
     8461 tggttttctt ttacgtttct attataagaa ttaacgggta ggcttactgt ctttcttggc
     8521 aaatttacaa tcaagccatt tgcagatata gtgcgcggct acttctgcca tgattgcaaa
     8581 aacaaaatca aaaagaattt tcaaacctat aacctcctcc ccttgccaga ttaggccggg
     8641 gtagcagaca gcaagactat tatagcataa ttgaaatatc caaatgattg gatttttgct
     8701 ataattttag cgaggtgatt gtgatgaaca aatatgttgg tttgcttgat aaaatccgag
     8761 taataaaaac gcaaccgtta ttggttcgct ttactttaca aacgattcat gaatcgatta
     8821 attgtgtagt tgcagatatt gaaattatcg ataaattgct aattatggat gatggaaaat
     8881 acaatattgc cgtcacaggt cacttcaata aacgaaatca gctagttatt gctagcatgt
     8941 atgttagaaa tcccgatcat tttacgcgat cgatgggcat ataaaaaaag aagagttgca
     9001 atcctaatgt aggactgcag ctctttttgt tttacataga aacaagaaaa atgaaaaggc
     9061 ctttttagga aggcgcgagc gccttctcaa ttgaaaaacc tctctcactc caaccgccac
     9121 cgccgttcga gaagaaagga agtgaacgtt gcacgttcac taagataaag ggtcttgcaa
     9181 agcaagacaa aatagaaaaa acttcctctc accaaaaggt tcgttcctgt tcgttatctc
     9241 tttattgatt tgccagaccg gcaacaagtt gccttttatc accaaaaagc gacaaggaca
     9301 agggtaaatg gcacgctgcg cgcccttgtc cttgtcgctt ttcgttgatt cattctggcc
     9361 aacaaatcaa taaagaaaga actaacgaaa ggaagtaaaa cctttcctaa gaggaggcag
     9421 aatcaatcat gcgaaagaaa tttgattatt ggggtgttcc cttcagcgaa ttattcccaa
     9481 actatcatgc accacatact gtcgaatgcg attgtggaca aagagcgaaa tgtatcaaaa
     9541 gctatcgttt gtatcaatgt ccaacatgcg gaaaaaaata caccttgtct tatggcgatt
     9601 atattttgat tgatgagaaa ggaaagaaac gctgatgaaa acataacata aattattgac
     9661 tgtaaaagaa gtcgttcaaa ttttggtgga caaagaagtc atttctgaaa aagtagcaga
     9721 agctttactt attccgcggt actggacgat agaaacccct ttagtagagg atgcaccgac
     9781 tatgctattt gaagacctag tgaagattgc aggatatgaa ctgcattatc aagaaaacat
     9841 ggaaacttat gaaaacgaat attggttaac caaattagag aactaaaaag gagaaaaaaa
     9901 tatggctcaa aattactatg acgaatttgt caaattacct ttggataaaa tggcacaaaa
     9961 aatggaggat atgacattcc tataccatga gacacgtgtt ccaaaaaaac attataagga
    10021 aagattgtcg gtagctgtgg aagaaatgat tgaatcaggt gtcgaaatga atctcattgc
    10081 gacgtactat cgaacactgg aagaactgaa aaaacaaaat gcaaaatggt ttttccaagc
    10141 cttactatgc ttggaagtag gtgtcaaacc aagcactatt aaaccttctg aatatcaagc
    10201 tttagaacta acgtatggga aatttgtcga aacgaaaaaa gccaagactg tttcaagtga
    10261 atggttagat tattttgaaa atatcaataa gtatggcgcc tattacacca tgaaaaagga
    10321 ggacaacgaa aatgaataag gtgatttatc aactaacaac ggaagatgtg tcacactttt
    10381 taacaaacaa agaacatttg aatgaagtaa tcagacggat tcaaaaagac tttagttgta
    10441 tggaagaaat gaagtacttt attcaaagag tcgaagaaca attgtatttg gaaagtgaaa
    10501 cgagtcaaac gaaggtcaca gtcagcaata attatttaga cgtgtataaa catcgtcctg
    10561 aaacggtaaa aaaaggaacg gagcttctac gactagaaac agaaaaatac atcatgaatg
    10621 tttacctaga aaggagtgaa ctggtcgaaa actttgtcag ctgcacgatt tgcaggaaac
    10681 actattactc agaatcagaa tattattcaa tttttgagag catggaatta atggaagaag
    10741 aaatggaaga gctaaacagc aaaaatgcga cgatagacga ttattatctt gtatttacta
    10801 gatttttgac gtgtggaacg gaatctatcg tgttaatggg aatggattat gaactcgctg
    10861 tacccgaagc atttttgagg gaatatgtag aagaagtaga taacccaggc gacgactggt
    10921 acacgacttt aactgatttt ttagatacct acacttacga cgatacagaa gaaatccaaa
    10981 atgaacttga ccgtaaacga atgccatatc aacgatttga aaggaaaaaa aggcaataat
    11041 catttatacc gaaaagtgag aatgtgtgaa ataagaacaa aaaccttgaa attaagggaa
    11101 tggttcttat ttcgcaccaa tcgctccaac cgcccccgcc gcttaggtgg tgcgaaataa
    11161 gcgggcaaag cccgataacc taagagaaag aaggagatcc atatgaataa aatcattcct
    11221 ctgttgttcg tactgtgtat tggcgagata cttatgcgtc atggtgcagc tgtacattta
    11281 aacttcgtag tattcttagg aatactagta ttttgtttga ttttttggcg ctttgtgtta
    11341 gcccttgtga gtctactatt caagttgatt gcagccatat ttttcatagg gttatttcga
    11401 tgaaaggaga gagtactaat gccaattgca ataggaaata aacggttacc cgtgacatta
    11461 gatgaaaaga gacaaaaaga attgcagcaa ctaaagcaga agtacggaaa aagtgaatct
    11521 aagattatgt gtattgcgtt agatctattg atcgcgcaag aaaaagcagg atttgatata
    11581 ccagcactaa aaaagtgacg tcacttttca tttgaagaaa caaaagtgat agcacttaat
    11641 tgttcctact atttagaata ttttctatgt cctttttatt ccattttgta tcaataacta
    11701 tgaaatcttt aaagtatcca gatcaatttt tttcttacct gattctaaag attttgtttt
    11761 cttaaacata ttatgatttc ctttcgacta ttttcatata aatgttaaca tagtttatgg
    11821 attcatggaa tgttaatcta atttaataga aaaggataat taagtatata cgttttttct
    11881 tatgtatgtt atactatgta tatacagaaa gaggtgtcta ctatggaaat gttacctata
    11941 aaaaaatggg gaaatagtaa tggccttaga ttgccaaagt atattatgga atatcttgga
    12001 attcatacag aagacaaagt gaagataata caagaagaag taaacggtca gaagcggcta
    12061 attatcgaag cggctaatat agaaaatgaa ttaacaattg aacagttatt tgaaaattac
    12121 actgatgaaa gaaatcatgt gacgattcaa aatttaggtg aagcagtagg taatgaaaaa
    12181 tggtgagaaa acctagacaa ggcgatattc tattattgaa tacagcacct cgatctggac
    12241 acgaacagac aggtaaaaga ccttatattg ttttaagtca tgatattatt gcggattata
    12301 gtaacgttgt tacagttgct ccaatttcta gtacaactag aaactatccg ctatatgtaa
    12361 atataaactc agaatatgaa atgaagacaa caggaaaagt attattagat caactaacga
    12421 caattgatta tgaagccaga gagtgtattt ttttggaaaa agcgcatgat agtttagttg
    12481 aggagttatt gatgaaagtt agaacagttt ttcaaaaagt aagcaaataa aatagaaaca
    12541 gcagcatgat caactattcg tgattgacca tgctgtcttt ttttattcta tatacggttt
    12601 gtctcgtaac attgtagtct tttgcaatct tagcgatcgc aacacctttt tttagatcct
    12661 caacgatgtt tttataaaca agacgacgtt ggggatcttt tgcattggca ctgtatagct
    12721 taggacgtcc tttataaaca ccgttcgctt ttgcaatctt aatgccttgt gcctgacgtc
    12781 gtttagattc ggtacgttct tgttcagcga tcatggccaa aatttgaatg atcaaatctt
    12841 taatgaattt atccaggaga ggattgccaa ttgcttcggc catgatcggt agacttgtga
    12901 tgatcagctg cacatttttc ttcttcaagt aattgactga agcgatgatc tcgtcgtaat
    12961 ttcttccaag tcgatcaata gcttccacaa taaaaatatc ttgatctcgg acgaaatcca
    13021 gtgcttcttg aaaaacaggt cgatgagtaa tcgttgcgcc agattgtttc tcaatgaaaa
    13081 ttctctctgc accgaatttt ttcatttctt caatctgccg ttgttcattt tgatcgatgg
    13141 atgagacacg tatgtatgca actctcaaaa tttttaccta ctttctgcaa ctatttaaaa
    13201 aacaccctaa tcatacacga gaaaaccaga tttttcaatg tcgcggtcgt gtctagttag
    13261 ggtatacctt atatagacaa aaactaatga tggaggaaat agtatgtgtc acttttcttt
    13321 ttaaatggca atattttttg taaataaatg tcaatcaaga aaatttaaac gattatgaca
    13381 ttaaaaatat attttatgaa ttttctagta tataacttga tttatctgtt aagatttatt
    13441 aagaaaacgt tttcttattt ttgatttcga ggtgatagac aatgaaaaat aagtttattt
    13501 tatctttagg tattttaact attggagtta gtgtaactgg aactacaatt cctacatttg
    13561 ctgatagtac aaatgaacca actactgtag tagataataa ccaagaatta actcctttag
    13621 ataggaacgg aatagccatt ggtaacccaa ctaacgactt aactgttact gaaaattatt
    13681 taatagtttc tccattactt gctcgagcag cttctaaaac gatacgagtg acaggaacga
    13741 tgatttttga taaagttggt tggccttcta gacctcctca atcacggaat tggaaagaaa
    13801 aaagaaatgg ttattggtac tatggaaaat tgtatttaca aagttataaa tcagctggaa
    13861 acaattggat tgcgacttat tcaggaacct taactagaaa gtagggattt tttatgccag
    13921 aatttgtgaa cacaccaaat ttttatcaag atagcgatat tctaagtaaa attaatttac
    13981 cgaaagaaga atcagcttta caagttcagc gaactttaca ggagacacaa aaaattcaaa
    14041 aatcaatttc taatctagaa gattctgaag aaaaaagaaa aaaaagagac caaaaaacat
    14101 atcaaaaaga aaaataatga ttttaaaaaa agagtgtcta gtcgacattc tttttttcta
    14161 attgaaagtg ttcataaaat cacccatttc tggacacttt ctttttttgc tttatttttc
    14221 aaaaaaacaa ttcatttcat gttcataaac ccataacaat atctatgttc agttaaacta
    14281 tatggataaa gttatgttac aataaaatta atgaaggagt gatttttttg aaaataggat
    14341 acgcccgggt atctactggt ttacaaaatt tggatttaca agaagacagc ctaaataaat
    14401 ttggttgtga aaaaattttt actgatcata tgagtggggc aaaaagtaat cgaccaggat
    14461 tagaaatggc cattgatttt gttcgctctg gcgatacact tgtcgtttgg cgcttagatc
    14521 gtttaggtag aaatatggaa gatttgattt caatcgtcaa tcgactgaat gagcgtggtg
    14581 tgagttttca tagtattcaa gaaaatatta cgatggacaa atcaagttct acaggacagc
    14641 tcatgtttca tttgtttgcg gcatttgcag aatttgagcg taatttgatc ctggaacgat
    14701 ccgcagcagg acgagcagct gctcgtgcaa gaggacggtt tggtggtcgt cctgaaaaat
    14761 tgtctgaaca agatttggaa ttactgaaga ctttagtgga tagcggtaca cctattaaga
    14821 ctattgcgga acggtggaac gtctcaagaa ccaccattta tcgttatttg gcaaaaatgg
    14881 aggagaaaaa tggaaagaca aattctcatt agtttttgtc atttaatgct gaaaattttt
    14941 gccatttatc tagaaaagtg acaatagtat gagaattttt tgtaagtgtc tactgataac
    15001 ttattctcaa atgttgtaag gattttattc atttgttaat attaaagaac ggaactccaa
    15061 aaaagtccgt actctaattt gcagtctctc actcttttag agtgagagtt tttattagat
    15121 tttcaaatta attagtaa
//
LOCUS       DAZKKZ010000063        15000 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.065, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000063 DAZKKZ010000000
VERSION     DAZKKZ010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15000)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15000)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15000
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.065"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..832)
                     /locus_tag="ACG8LA_002241"
     CDS             complement(<1..832)
                     /locus_tag="ACG8LA_002241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HFQ0204522.1"
                     /translation="METLSVVQSLLIALWVAAVMSRWLGGGATLTLRFSPLMTGLVVG
                     LIMGEVAQAMIVTAALQMIYMGVFSPGGSMPAEPSIAAAIAVPVALLGDLSPEAAIAV
                     AVPVGLLGSYLYQFRFFINTFLGKYTDKAVEDLNTKAMARSIILYPTVASFLLFVPLV
                     FIALYLGAPLIADVIKALEGTVVIHILEVVGGGLAAIGIATTVYVIGRKDYLVFFFLA
                     YFMSVVLKSLDITMVTYAIFGIIIALIFVQSQKGKQVQPATSNNNSASFDDEDDYDDG
                     F"
     gene            complement(846..1643)
                     /locus_tag="ACG8LA_002242"
     CDS             complement(846..1643)
                     /locus_tag="ACG8LA_002242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HFQ0204523.1"
                     /translation="MGYSANLARIDFGVIPTLASNCAPWTPLAVMYKENGQAEGKTEH
                     FYRQAAFFITDPQLVIDSPVPYFIAGLADTLAKWYESELILEQDFLQDESFLKLAQDT
                     AKICKEEILNHSAKAIQDMAQRKLTSEFKQLSEIIFAVAGLVGGLGDKYARNAAAHAM
                     HDAISKYIPESHRFLHGEKVAYGIFYQLALEGRWEKIDELYPLYRELELPVSLEQMGL
                     FPKDKQIIDKMAEFIDSKEKVHLIPIEVTQKSLIQSMMELEGYIRKI"
     gene            complement(1676..1960)
                     /locus_tag="ACG8LA_002243"
     CDS             complement(1676..1960)
                     /locus_tag="ACG8LA_002243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase"
                     /protein_id="HFQ0204524.1"
                     /translation="MMKKMVNGLKVKTGPQFYLYEEGGISKVSDLLKSYGAKRVLVTH
                     GTVSWEKALPKLVFLNDETIQFFYHRYSGECSYAEARRIATIIKKMKSIS"
     gene            complement(1957..2958)
                     /locus_tag="ACG8LA_002244"
     CDS             complement(1957..2958)
                     /locus_tag="ACG8LA_002244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-isomer specific 2-hydroxyacid dehydrogenase
                     family protein"
                     /protein_id="HFQ0204525.1"
                     /translation="MPDYHIAIVNSSSFGRVFPHHLERLKSVGDVHFFTVDQEIPGKE
                     LAELLKGFNIIIASVTPFFRRDFFENKDELLLISRHGIGYNNIDLKAAKEHQTIVSII
                     PALVERNAVAENNITNLLSMLRRTTQAQARVKDDRWEDRAEFVGRTLFNKTVGVIGAG
                     NTGSGVIEILRNGFRCDVLAYDPYKSDLYIESFGAKKVELQELLEQSDIICLCANLTE
                     ENYHMISDKEVDQMKENVYLSNSARGALVDEEAMINGLKSGKIAGYATDVLEEEPGRQ
                     DHPYLAFEQVVITPHISAYTRECLEAMGEKCVRDVEQISQHLLPERSVQTKSNYIKG"
     gene            complement(2960..3862)
                     /gene="gnd"
                     /locus_tag="ACG8LA_002245"
     CDS             complement(2960..3862)
                     /gene="gnd"
                     /locus_tag="ACG8LA_002245"
                     /EC_number="1.1.1.343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphogluconate dehydrogenase
                     (NAD(+)-dependent, decarboxylating)"
                     /protein_id="HFQ0204526.1"
                     /translation="MEIGVIGLGKMGLNLALNLKEHHHKVQGLDISSTAVSQARENDI
                     PAYQEISEFLATFEQKKIIWLMLPAGEITENMLRKLFPKLGPGDIIIEGGNSYYKDSI
                     RRAEEFQKNEIGYLDCGTSGGIEGARHQACLMIGGDKETFLSVEQLFKDVAIERGYLY
                     AGASGSGHFLKMIHNGIEYGMMQAIGEGFQLVQKSEYAFDLEQVARVWNHGSVIRGWL
                     MEIMEDQLNEHPNLSNYRGIVSASGEAKWTVETALEMAVPVPVIATSLFMRNLSQEED
                     SFSAKVVSALRNGFGGHEIVEKGE"
     gene            4026..4874
                     /locus_tag="ACG8LA_002246"
     CDS             4026..4874
                     /locus_tag="ACG8LA_002246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HFQ0204527.1"
                     /translation="MSVSIRLQIKTMYNDFSPKEQAIADYILENPSKVSHSPISNLAS
                     ELGIADSTFFQFTKKLGYNGFKDFKMAMLIQENDLSAISIHENIQKTDTELTMAQKVF
                     ESSISTLNDTKKLLQQKDLKKAATIINESKRVYFFGVGGSEIVATDAYHKFLRSPIAT
                     SHSTDYHIQLMEASLLTEKDCAVLISHTGQSKETIHIAETVRKTGAKTIVITSQANSS
                     LAKLGDVVFISISEETEFRSEALASRISQLSILDSLYVILMFYNEKESRRSIAKVRHT
                     ISEIKE"
     gene            5520..5726
                     /locus_tag="ACG8LA_002247"
     CDS             5520..5726
                     /locus_tag="ACG8LA_002247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3955 domain-containing protein"
                     /protein_id="HFQ0204528.1"
                     /translation="MKAIHISLLFFASALILFAIHLCSQPYINNNGILVEPAFFCLPL
                     GFLSLLASAGFGFVAFFKRSKQQI"
     gene            complement(5928..6929)
                     /locus_tag="ACG8LA_002248"
     CDS             complement(5928..6929)
                     /locus_tag="ACG8LA_002248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFQ0204529.1"
                     /translation="MKWFKRIVIAVPVIIVVILVTVFLINQITPKPISLLVRKQFDTS
                     EKEQVYARPDDFQQKIEQIDIKKEISYPSKYKNNNMDIYTPKVEKKKLPILFWMHGGA
                     YVGGDKNDCRDYLEYLCSDTQQIIVNIDYERSPEAKHPTPVIQLNEAIQAAKKEIKDQ
                     ADWSNISIGGNSAGAQISGEYLLALQNEEIKKADHLDPTLENKQITKFISLSGLLDPS
                     ALTQVSDKISSFLYEKCGWAYFDNKDFEQSEKVKSLALVRHADRWTQNTFLTDGNTNT
                     FTKQMEEVTSVFEKAGVKVTKVDYAEKNAVLNHEYQFDFSNKQAQETYQKLVMFFKE"
     gene            complement(6934..8846)
                     /locus_tag="ACG8LA_002249"
                     /pseudo
     CDS             complement(6934..8846)
                     /locus_tag="ACG8LA_002249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311095.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
     gene            complement(9014..9520)
                     /locus_tag="ACG8LA_002250"
     CDS             complement(9014..9520)
                     /locus_tag="ACG8LA_002250"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase family protein"
                     /protein_id="HFQ0204530.1"
                     /translation="MSNTADAIVVIDLQKGVCFDSSPIHELETVTALVNKRIKTYETI
                     GKPVIFVQHEDAQLVPQTKPWELLSELSIPEHSYFVRKTHANSFYKTNLSVLLTELDC
                     HSIELCGAQAEYCIDTTVKFAHGLGYQLMMCRGATTTYDNPFMKAKETIAFYEKIWDK
                     RFLTFLEQ"
     gene            9680..10120
                     /locus_tag="ACG8LA_002251"
     CDS             9680..10120
                     /locus_tag="ACG8LA_002251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HFQ0204531.1"
                     /translation="MMIKLYTGSGCSSSRRAKRWLIVHDIPFIEQNLIRQPLTKNEFI
                     HLLKLTNNGVTEMLSTHSISYKNLVHRIDELSLSELYIEIRTSPSLLKKPIIYDQSAK
                     LLTGFSEDKIRMFLSKTKRKQELNELLLSGHLVDFKENNLFAMS"
     gene            complement(10146..11261)
                     /locus_tag="ACG8LA_002252"
     CDS             complement(10146..11261)
                     /locus_tag="ACG8LA_002252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204532.1"
                     /translation="MKNYHLSCSLKKGNPIEGEEYRIRYFFHLMYWQSFDENHSDILS
                     SIKNKRQLLEKFAKHAPYTRSIDRKKWISLLRISLQRMKQGHSITYVPEEMNKFVHPL
                     ITKEEFTHYILEPFFEANFWSMNHITPTEQAYLYFMFGVMNTYLEEDLLDTPDKVQES
                     WGWIESSIVENFEKNFKICFTTSEKNYLYVNLAMIHLYSRVFGTKKKVDAFGKSAEDR
                     DFQHIFPVMYPIMQQFFSGVARRIPELNTYYEKNRRLIFQYCMLVRDIFIKHEQPVIF
                     YIQSKYGKTQELWAKKRILSMTERPIKYSASADQLPDIVISDYPIDKKAYDQTNTQIF
                     YWNGQPTKNDWARLKAEIIKIRNEKNRSILEKLDFVN"
     gene            complement(11306..11662)
                     /locus_tag="ACG8LA_002253"
     CDS             complement(11306..11662)
                     /locus_tag="ACG8LA_002253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204533.1"
                     /translation="MFEEFIDINERQVYQFLNYCYERDEKLYVVKDIALDLNYTLAKM
                     NSVIQQAESFCERYPEYKLSFLSENKMIKVEFSSQFLLSKVYSILLEGTIGYILLDSL
                     YKGTYQSLENLSQKII"
     gene            complement(11960..12934)
                     /gene="sgrA"
                     /locus_tag="ACG8LA_002254"
     CDS             complement(11960..12934)
                     /gene="sgrA"
                     /locus_tag="ACG8LA_002254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored fibrinogen/nidogen-binding
                     adhesin SgrA"
                     /protein_id="HFQ0204534.1"
                     /translation="MKKTATVLFVILGLSIIAAMIGISTSANERANENLSFTVKTDRI
                     VYDMTQQVITIPVKPNKSVNASDVHAVLTYGWDGNGSSEKVIGEVYLKDVQWTAGIEY
                     TIMISAELSIDEIKSKDKVDLIVFYDGQMTITENLKPSSWTVVGPPSSTDSTSSESST
                     ENTSGESSTESTSSESSTENTSSESSTESTSSESSTGSTSSESSTESTSSESSTGSMS
                     SESSTGSTSSESSTGKVNNELDLVPIIPTKEQKRNAGSNLKSVLKQPDFVSRGIDHQE
                     KAKETDNRKSDLPETGSRTLNKLITWMGVLLILIVGASYFRSLFHRVK"
     gene            complement(13130..13969)
                     /locus_tag="ACG8LA_002255"
     CDS             complement(13130..13969)
                     /locus_tag="ACG8LA_002255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="HFQ0204535.1"
                     /translation="MIRIIRLIGSVLIVLVGFVLGILVNNALADMFIGNSEWIGAIAG
                     TVGHLAVFLLALFLASKVEGKRIEDYGVSVRGKDWGYLAGGLVVGIGVFLLITSPLYL
                     TGAYRLDSGNANIVPLITSFILFIAVGASEELLFRGFFQHQMLRFGPLIAMIGSAALF
                     ALLHGLNPNMTFLAVFNIFLAGCFFSALIYSTGSLFTAIGAHITWNWTQGAILGIPVS
                     GTQEQGFFSTLIQSQNTIITGGNFGAEASISTTLFLLVLIVGLLLYAYKTKRMKKYTA
                     VYQ"
     gene            14154..>15000
                     /locus_tag="ACG8LA_002256"
     CDS             14154..>15000
                     /locus_tag="ACG8LA_002256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HFQ0204536.1"
                     /translation="MGNFLKKQLLIMCLSACAILLFSGCSKSNETIATFKGGTLTVQD
                     FYDNPKVKSNNQTLLKKMIVFKAFDDVYGKEISSKEVTKEYNEQIKKLGPNYKEQLKA
                     VGQTEETYKKLFKQMLAFQYGLKANVKLTDKDLDTAWKEFYPEVSTQIILFSTKEEAD
                     KAKKEANEGENFSKLVQAYGKNKTLKETDGKMNFDSTNPEIPTEVKKAAFKLKNGEVS
                     DIIPVTDPTTYQQSYYLVKMVKKQDKGSNKDKYKSELEKIATEAKTLDTEFMDKTIRK
                     VMKKDN"
BASE COUNT         4505 a         3072 c         2326 g         5097 t
ORIGIN      
        1 aaaatccgtc atcatagtca tcttcgtcat caaaagatgc tgaattgtta ttgcttgtgg
       61 caggctgtac ttgtttccct ttttgcgact ggacaaagat caaagcgata ataatcccaa
      121 aaatggcata agtaaccatc gtaatatcta aagatttcaa aacaacactc ataaaataag
      181 caaggaagaa aaagaccaga taatcttttc gaccgataac gtatacagtt gtcgcgatac
      241 cgattgccgc taaccctcca cctactactt caagaatgtg gataacgact gttccctcta
      301 aagctttgat tacatcagcg atcaatggcg cccctaaata taaagcaatg aaaacaagcg
      361 gaacgaataa taaaaatgag gcaaccgttg gataaagaat aattgatcgg gccatagctt
      421 ttgtattcaa atcttctaca gctttgtctg tatatttacc taaaaaagta ttgatgaaaa
      481 aacgaaactg atacaagtaa cttccgagca atccgactgg caccgcaacg gcaatcgctg
      541 cttctggcga cagatcccct aataatgcga ctggtactgc gatagctgct gcaatagatg
      601 gttcagctgg cattgatcct cctggagaaa aaacccccat ataaatcatt tgcaaagcgg
      661 ctgtaacaat catcgcttgt gcaacttccc ccatgatcaa cccgacgact aatccagtca
      721 tcaaaggaga aaaacgtaag gtcaacgtgg ctcctccacc taaccagcgg gacataaccg
      781 cggctaccca taaagcaatc aacaaacttt gtactacact taatgtttcc atgtgtcctc
      841 ctccttcaga tctttctgat ataaccttcc agttccatca ttgactgtat cagtgatttc
      901 tgtgttacct ctataggaat caaatgcact ttctctttcg aatcaataaa ttcagccatt
      961 ttatctatta tctgtttatc tttcggaaat aatcccattt gttctagaga aaccggcagt
     1021 tctaattccc gatacaaagg atataactcg tctatttttt cccagcgacc ttctagtgcc
     1081 agttgataga aaatcccata cgctactttt tctccatgta gaaaacgatg gctttccgga
     1141 atatatttac tgatagcgtc atgcatagca tgtgctgccg catttcttgc gtatttatct
     1201 cctaatcctc caactaaacc agcaacagca aagataatct ctgaaagctg tttgaactcc
     1261 gatgtcagtt ttctttgtgc catatcttgg attgctttag cagaatgatt caaaatctct
     1321 tctttgcaga tcttcgcagt atcttgtgct agcttcaaaa atgattcatc ttgcaaaaaa
     1381 tcttgttcta agatgagctc agattcatac cattttgcta gtgtatctgc taacccggca
     1441 atgaaatatg gaacagggga atcaatcact aattggggat ctgttataaa aaaagcagct
     1501 tgtctgtaaa agtgttctgt tttcccttct gcttgtccat tctccttata catgacagca
     1561 agaggtgtcc atggagcaca attactagct aaagtaggga tgactccgaa atcgattctt
     1621 gcaagattgg cactataacc cactagatcg gtcagttttc ctccgccaac gccaactacg
     1681 aaatcgattt catttttttg atgattgtag ctattcgtct ggcttcagca taactacatt
     1741 ctccagaata acgatgataa aaaaattgaa tcgtttcgtc attcaaaaat actaatttag
     1801 gtagcgcctt ttcccatgat accgttccgt gggtgaccag tactcttttc gcgccgtatg
     1861 atttcaagag atcagaaact tttgaaatac caccttcttc atataaataa aattgagggc
     1921 ctgttttcac ttttaaaccg ttcaccattt tcttcatcat ccttttatat agttgctctt
     1981 tgtctggaca gaacgttcag gaagaaggtg ctgactgatc tgttcgacat ctctgacaca
     2041 tttttcaccc attgcttcta aacattccct tgtgtaggcc gatatatgtg gcgtaatcac
     2101 tacttgttca aacgctaaat acggatgatc ttgacgtccc ggttcttctt ctaaaacatc
     2161 tgtggcatat cctgcgatct ttccgctttt cagaccatta atcatcgctt cttcatcaac
     2221 tagagcgcct cttgcactat tagatagata aacattttct ttcatctgat cgacttcttt
     2281 atcagaaatc atgtgatagt tctcttctgt caaattcgca cataaacaaa tgatatctga
     2341 ttgttccagt aattcttgaa gttctacttt ttttgcacca aagctttcga tgtataaatc
     2401 tgatttgtaa ggatcataag ctagaacatc acagcgaaaa ccgttacgca aaatttcgat
     2461 tactccgctt ccggtatttc ctgcaccaat cacaccaact gttttgttaa acagcgtcct
     2521 accgacgaac tccgcccgat cttcccatcg atcgtccttg actcttgctt gtgcttgtgt
     2581 cgtgcgtcga agcatggaca acaaattagt tatattattt tctgctacag catttcgttc
     2641 aactaaagca ggtatgatag atacgattgt ctggtgttct tttgctgctt ttaaatcaat
     2701 attgttgtaa ccaataccat gtcgggaaat caatagcagt tcatctttgt tttcaaaaaa
     2761 atctcgtcga aaaaatggcg taacacttgc aataatgata ttgaatcctt taagtaactc
     2821 cgctagttct tttcctggaa tctcttgatc aacagtaaag aaatgaacgt ctccaactga
     2881 ctttaatctt tccaagtggt gtggaaagac tcttccgaaa ctgctggaat taacgattgc
     2941 tatatgataa tctggcattt tactcaccct tttcaactat ttcatgtccg ccaaacccat
     3001 ttcttagtgc tgaaactact tttgctgaaa aactatcttc ttcctgtgaa agattcctca
     3061 tgaacaaact agttgcaatt actggaactg gaacagccat ttctagcgct gtttcaaccg
     3121 tccattttgc ttcacctgat gcagaaacga ttccccgata attacttaaa ttgggatgtt
     3181 cgtttaactg atcttccatg atttccatca gccagccgcg aatcaccgaa ccatgattcc
     3241 aaacacgtgc gacttgttcc aagtcaaaag catactcact tttttgtaca agttggaatc
     3301 cttcaccgat tgcttgcatc attccatatt cgattccatt atggatcatt ttcaagaagt
     3361 gtccgcttcc ggatgcacca gcatacagat atcctctttc aattgctaca tctttgaata
     3421 attgttccac ggatagaaaa gtttctttat ctcctccaat cattaagcag gcttgatgtc
     3481 gtgctccttc gattcctcca gaagtcccac aatccaagta accgatttca tttttctgaa
     3541 actcttctgc tcgacggatt gaatctttat aataagagtt tccgccttca ataataatgt
     3601 ctcctggtcc gagttttgga aaaagttttc ttaacatgtt ttcggttatc tctccagcag
     3661 gaagcattaa ccagatgatt tttttctgct caaaagtagc tagaaattca gagatctctt
     3721 gataagcagg aatgtcattt tctcttgcct gactaacagc tgtacttgaa atgtcgagtc
     3781 cttgtacttt gtgatggtgc tcttttaagt ttaaagctaa attcaatccc atttttccca
     3841 aaccaattac accaatttcc atgatagcgc ctccatttct tataccctca ttatacaaaa
     3901 aaattttttt gtaaatagat tttacaaaaa tattttttgt ttgatttttt cctactctcc
     3961 ttgtatcttt aacattaatg agaacggaaa aaatgataat cttattatga aaatgaggaa
     4021 ttctcatgag cgtctccata agactacaaa tcaaaacaat gtacaacgac ttcagcccaa
     4081 aagaacaggc tatcgccgat tatattttag aaaatccaag caaagtaagt catagtccta
     4141 ttagcaattt agcaagtgaa ctgggcattg ctgactctac tttttttcaa tttacaaaaa
     4201 aacttggtta taatggattt aaagatttta aaatggccat gttgatccaa gaaaatgatc
     4261 tatctgctat ttctatccac gaaaatattc agaaaacaga tactgagctc actatggcgc
     4321 aaaaggtgtt cgagtctagt atttcaactt taaatgacac aaaaaagttg ttacaacaaa
     4381 aggatctaaa aaaagcggct actattatca atgaatctaa acgtgtctat tttttcggtg
     4441 ttggcggttc agagattgta gcaactgacg cttatcataa atttttgcgt tcccctatcg
     4501 caacttctca cagcacggat taccatattc aattgatgga agcttcttta ttgacggaaa
     4561 aagactgtgc tgttttgatt tctcacacag ggcaatcaaa agaaacaatc catattgctg
     4621 aaaccgtaag aaaaactgga gcaaaaacaa tcgttattac tagccaagct aattcttccc
     4681 ttgctaaact tggcgatgtc gtttttattt ctatttctga agaaacagaa ttccgatctg
     4741 aagctttagc ttcccgtatt tctcaactaa gcattttgga ctctctatat gtgattttga
     4801 tgttttacaa cgaaaaagaa tcacgtcgtt ctatcgctaa agttcgacat actatttctg
     4861 aaatcaaaga atagcaccat aacagaaaaa gcgaaaaatc cataaaacaa aaaaagccac
     4921 taccaaatat ttggtagtgg cttttttggt tctgcaaggg tggtacagaa catcaatagt
     4981 cggtgggtta gaacgtatgt catcgcatct ttggagaagg ttgtattggt attattcgag
     5041 ttacttgtta gatgcgataa caaagttagt atacagtagt aaaaaattta tcttttcttt
     5101 tttttattat ttttgtttct tattttctaa aaaattaaaa aaaattttgg tgaattaagt
     5161 atttccttga taacactggc ttttggcctc attttaggtt atcatttgta attttatttc
     5221 acagttgata tgattgttat gtaaaataaa aaagtttagg atacatcgaa tttttgggga
     5281 aattcttttg ggggtatcct aaatcttttc tattatattc ccatattttc tattattggt
     5341 ctagacgtat gatggtaaac tttgtaccta tctgattgct gaatcattaa ttgcttatca
     5401 ttagccatct ttgtttcaag ttcgctagat gatcatttta ttcacatcct aacaaacttg
     5461 tcacatttat agattcttaa tctatttatc atacaattat aaaaaaggag gtgctgctta
     5521 tgaaagctat ccatatttct ttgctttttt tcgctagtgc attgatttta tttgctattc
     5581 atctttgttc ccagccttat atcaataaca acggaatatt agtggaacca gcattctttt
     5641 gcttaccact cggctttttg tcccttcttg cctccgcagg cttcggattt gttgcttttt
     5701 ttaaacgatc aaaacaacaa atctgactta taaaatttac gtaaaagaga tcgtgacaat
     5761 aatcgtgtga tattcccaaa tttcgaataa aaggtgcccc ttgccatctc taactcctca
     5821 gtcacaagtt acaatattca taaaccatga aaagcttgtt tattgaaatt gctccttgtg
     5881 acttggagct aagtgacaga ttacaacctc ttttgcatca taagacttta ctccttgaaa
     5941 aacattacta acttttgata tgtttcttgc gcttgtttat tgctgaaatc aaactgatat
     6001 tcatggttca aaacagcatt tttctccgca taatctactt ttgtgacttt cacccccgct
     6061 ttctcaaata cagaagttac ttcttccatt tgtttcgtaa acgtatttgt atttccatcc
     6121 gttaagaatg tgttttgcgt ccaacgatcc gcatgtctga ccaaggctaa acttttgacc
     6181 ttctctgatt gttcaaagtc cttattatca aagtaagccc atccacattt ttcataaaga
     6241 aagctagaga ttttatcact tacttgagta agtgcagaag gatccaacag accagacaaa
     6301 gaaataaact tcgtaatctg cttgttctcc aaagtcggat caagatgatc agctttttta
     6361 atttcttcat tttgaagtgc taacaaatat tctccactaa tttgtgcacc tgccgaattt
     6421 ccaccaatcg aaatattcga ccaatctgct tgatctttta tctctttttt agctgcttga
     6481 atggcttcgt tcaattggat aactggtgta ggatgttttg cttccggtga tcgttcataa
     6541 tctatattta cgatgatttg ctgcgtgtct gaacatagat attccaaata atcacgacaa
     6601 tcatttttat cccctcctac atatgcgcct ccatgcatcc agaaaagaat cggtaatttt
     6661 ttcttttcca ctttcggtgt gtagatatcc atattattat ttttgtactt tgaaggatag
     6721 gatatttctt tttttatatc gatttgttcg attttttgct ggaaatcatc tggtcgggca
     6781 tatacttgtt ctttttcact tgtgtcaaat tgttttctaa caagcaagct aatcggcttt
     6841 ggtgtgattt gattaatcaa aaatacagtg actaaaataa ctacgatgat aactggtact
     6901 gcaatcacta ttcgcttgaa ccatttcatt catttaccct ctctttcttc gccaaatcca
     6961 tgtgataatc gtgctaacag ataaaaatcc acctgaataa atgagaagcg aatgtttctt
     7021 ttctccagtt ttcggcaaca ttcttttttt gcatctgtct ttttttgtac tttcactgtc
     7081 atctgaatcg gttgcgtatc atcacttgat tgatcctctc gaggttcatt ctttccctta
     7141 ttgtctgcat tctctgtcgg atcttgcttt tttggtggag ctactgggat ttttttgtaa
     7201 tagaaaataa tagttggtat cgtctcatta aaaatccctt cagtcggtcc ttcaacattt
     7261 gctaattcgt atccttcgaa tgtcttttgc tctgtcatat aattttctcc ataagctccg
     7321 taaagctgga tttcgtcctg gtctttgagt agacttttat tgttttcatc cacatacttt
     7381 acgtttatct gatcatggaa cactactttc aaaaagtccg ttacatgttt cgtgtaggca
     7441 gcatggtcaa cttcctgtgc ctttccatgc cctgctcctt ctactaataa aagatcttta
     7501 taccctcctg ataactcata taatttttgc gcgttagaca caggtactac atcatctgct
     7561 gttccatgga taatcaattt aggcaatgaa tctgacattc caatcgtagg tagagcagct
     7621 tttgtatcca aatgcatctc ctgatcaaaa tagtattgtt tcaaaaggcc cataaataaa
     7681 tcttcatgct cttgatcccc aatgatgtct aactgatttt ttatggcatc cggtagtgcg
     7741 ggggctactg tctggctgta cgtaaaacgt agttgttcat caattgatgc aaatccgcaa
     7801 ttttcaataa ttcctttgac attgacagga atatctttcg ctaatacaga catcatcgta
     7861 gctgctccca tcgaaccacc ataaagtaaa atcttttgag atggccgctc tcgaacttct
     7921 tgatttatcc agtaaaggac gtcatctgac tcatattgtc cataggtcac ataatcgcct
     7981 ccgctattac cagtcgctct ggaatcaaca aataataaat tatacccggc cttataaaaa
     8041 tcattgtatt cttctgtaac gatcccgtta ttccaattcc ctcgaaatcc gccatggatc
     8101 atgactgttt tatctgaacc ttgatcgaca taatatgcat atacatccat cattttgcca
     8161 tcttgtttgt ttagtacagt ttgatgaagt tgttttgtat ttggatagaa gcctgtgttt
     8221 tctgtaggcg ttgtcccatc atctgtacct ccaagcatcg acatcaacac actgtttttt
     8281 gcaaaagcga tatcgtacaa tagataagta gcaatcagat gtttgataat ctctttatct
     8341 acaccataat cattaacagc aagctcagtg actaataact ctattaattt tgacttgatg
     8401 tcttctgttg gtccattaag tatttctgtc atctgtttac cgaagtaatt caaatattct
     8461 ttaccattga aattttcacc tttaccgata tcatcatttt ctgtcccatt ctctttgtca
     8521 cttactttag cagaagagga ttcgtcgttt gacatttttg tagctgttgc ttcttctgtt
     8581 tgttggttat ctgtggtagc ggtcgtttct tgatctgtgc tagtaacaga tgtctcaacc
     8641 gttgtttcag tatttgtttc tgtttgtgaa gtactcgatt tcgtttcatt tccagcatca
     8701 gtagtttctg tggtttctac ctcccgagat tccgattcgg aagaaatgct ctctccatat
     8761 actgtccatt gcgggacgct tgtacttaca gcaaataaga tgaccaacgc tccctttaat
     8821 acttgttttg ttctcaagct attcactcct ttttatgttt ctaggagaat tatatgtaaa
     8881 cgcaaacatt ttttatacaa aaaataaatg gtttatccca taaaaataga acaggattat
     8941 tttctcattt tacgtaataa agcagaatgg ataaaccagt atccattctg ctttttttaa
     9001 acgaagaaac aacttattgc tccaaaaatg tcagaaatcg tttatcccaa attttctcgt
     9061 aaaaagcgat tgtttccttt gctttcataa aaggattatc ataagttgtc gttgctcctc
     9121 tacacatcat aagctggtat cctaatccat gagcaaactt cacagtcgta tctatacaat
     9181 actctgcttg tgccccacat aattcgatcg aatgacagtc caattcagtt aataaaacac
     9241 tcaaattagt cttataaaat gaattcgcat gggtttttct cacaaaataa ctgtgctcag
     9301 gaatagataa ttccgacaat agctcccatg gttttgtttg tggcactaat tgagcatctt
     9361 cgtgttgaac gaaaataact ggtttcccaa tcgtttcgta tgttttgatt cttttattca
     9421 ctaatgctgt cactgtttct aattcgtgta tcggcgaaga atcaaaacat accccttttt
     9481 gtaaatcgat cactactatt gcgtcggctg tgtttgacat acttgtgcct tctttctttt
     9541 ttcttgattt aatagtattt cttatctagc tagttccatt atacgtgaca acattttctt
     9601 attttacacc tctaaatggc acttttcgac tatttcttca tgttattatt tcataaatac
     9661 ttagctattg gaggaatgta tgatgattaa attgtataca ggttctggct gctcgtcttc
     9721 aagacgcgca aaacgttggc ttatcgtcca tgatataccg tttatcgaac agaacttaat
     9781 tcgtcaacca ctaaccaaaa atgaatttat ccacttacta aaattgacaa acaacggcgt
     9841 gaccgaaatg ctctctactc attctattag ttataaaaat cttgttcaca gaatagatga
     9901 actcagtttg agtgaactat atattgagat tcgtacatcc ccttctttat tgaaaaaacc
     9961 gattatctac gaccaatctg caaaactttt gactggattt agcgaagata aaatcaggat
    10021 gttcctttct aaaactaaaa gaaagcaaga gctcaacgaa ctcttgcttt ctggtcatct
    10081 tgtcgatttt aaagaaaata atctttttgc aatgtcttaa ttttggcata aacaatctgc
    10141 ttttcttaat taacgaaatc caatttttcc aatatggatc tatttttctc attcctgatt
    10201 tttatgattt cagctttcag acgcgcccaa tcattttttg taggttgtcc attccagtaa
    10261 aatatctgtg tattcgtttg atcatatgcc tttttgtcga taggataatc gctaatgaca
    10321 atatcaggta actgatcagc ggatgcacta tattttattg ggcgttcagt catagataat
    10381 atccttttct ttgcccataa ttcctgtgtt ttaccatact ttgattgaat atagaatatg
    10441 acaggttgtt cgtgttttat aaaaatatcc ctgactaaca tacagtattg aaaaatcaac
    10501 cgtctgttct tttcataata agtattaagc tctggaattc tgcgagctac cccactaaaa
    10561 aactgttgca tgattggata catcactgga aatatatgct gaaaatctct gtcttctgct
    10621 gattttccaa aagcatccac cttctttttt gtcccaaaaa cccttgaata caaatggatc
    10681 attgccaaat tgacatatag ataatttttt tctgaagttg taaaacaaat cttgaagttt
    10741 ttttcaaaat tttctacaat agacgattca atccagcccc aactttcttg tactttatct
    10801 ggagtatcca acaaatcttc ttccaaatag gtgttcatta caccaaacat aaaataaagg
    10861 taagcttgct ctgttggagt gatgtgattc atcgaccaga agtttgcttc aaaaaaaggc
    10921 tctagtatgt aatgcgtaaa ctcttctttt gttatcaatg gatgcacaaa tttgttcatc
    10981 tcttctggga catacgtaat cgagtggcct tgtttcattc gttgcaacga aattcttagt
    11041 aggctgatcc atttctttct atctatacta cgcgtatatg gcgcatgttt cgcaaatttt
    11101 tctaatagtt gacgtttatt ttttatactt gataatatat cagaatgatt ttcgtcgaat
    11161 gactgccaat acatcaagtg aaaaaagtat cggatacggt attcttctcc ttctatcgga
    11221 ttaccttttt tcaagctgca agataaatga tagtttttca aaatagtatt aagttctctt
    11281 aattttcttt gaatcgtacg caaacttata taattttttg actaagattt tctaaggatt
    11341 gataagtacc tttgtaaagt gaatccagta aaatataacc aatcgttccc tctaaaagta
    11401 tagaataaac tttactcagt aaaaactgag aagaaaactc gacttttatc atcttgtttt
    11461 ctgaaagaaa agataattta tattctggat acctttcgca aaacgattct gcttgttgaa
    11521 tcaccgaatt catcttagcc agggtgtagt ttagatctaa agcgatatcc ttcaccacat
    11581 ataatttctc gtctctttca taacaatagt tcaaaaattg atatacttgc ctttcattga
    11641 tatcaataaa ttcttcaaac aaagtacata ctccttttta tctattattt agacttattc
    11701 cgacagctac atgaataacg tacaaataga ttcgttactg atttttcaga gatactacca
    11761 tgcgcagtgt gcattgtcaa ttattcttgc tcttattttc catttgtgtt cctgttattt
    11821 cctgtttctc aaatatgtta gtaaacaaaa atagatctgg caaagctaca acttcgccag
    11881 gcaatacagc actctcgaat gaaatattca ctcaaaaatc tatcgtttta ttcaatttta
    11941 gatctgttgc ttttattctt tatttcactc gatggaagag agaacgaaaa tagcttgctc
    12001 ctacaatcaa aatgagtaac acacccatcc atgtaattag cttgttcaag gttctactac
    12061 cagtttctgg taaatcgctt tttctattat ctgtttcttt cgctttttct tgatgatcaa
    12121 ttccacgaga aacaaaatca ggctgtttta gcacactttt taggttgctc cctgcatttc
    12181 tcttttgttc cttagttggt atgataggta ccaaatcaag ttcattattt acttttcctg
    12241 tgctgctttc gctgctcgtg cttcctgtgc tactctcact actcatgctt cctgtgctac
    12301 tttcactact cgtactctcc gtactgcttt cgctgctcgt gcttcctgtg ctactttcac
    12361 tactcgtact ctccgtactg ctttcgctgc tcgtgttttc tgtgctactt tcactgctcg
    12421 tactctctgt actgctttca ccgctcgtgt tttctgtact gctttcacta cttgtgctat
    12481 ccgtactgct tggcggtcca acaactgtcc aactgcttgg tttcaaattc tccgtgatcg
    12541 tcatctgtcc atcataaaaa acaatcaaat caactttatc tttactcttg atctcatcaa
    12601 tcgatagttc tgcagaaatc attattgtat actcaatacc agcggtccat tgtacgtctt
    12661 ttaaataaac ttccccaata actttttctg aacttccatt accatcccaa ccatatgtta
    12721 gaacagcatg tacatcacta gcattcacgc ttttgtttgg tttgactgga atagtaatga
    12781 cttgttgtgt catgtcataa acaatccgat cagttttcac agtaaatgaa agattctcat
    12841 ttgcccgttc atttgcagaa gtactgattc caatcattgc tgcaattata ctcagcccaa
    12901 gaataacaaa taatacggtc gctgttttct tcatttctat cactctccat ataattacct
    12961 tctatttgat aaaggaatta tataaaatga aaatgatgag aacacgacag tcagttgtga
    13021 aaatctaaca aaagatgtcg tgtattcgct tgaatttgtt tactttttcg tttaatcaat
    13081 gacagactta aaaaagcaag accgatatca gccttgcttt cttcatcttt tattgataaa
    13141 cagcagtgta tttcttcatc cgctttgttt tatatgcata gagtaacaaa ccaacaatca
    13201 agactaacaa gaataatgta gttgatatag atgcttcagc cccaaagttt cccccagtaa
    13261 ttattgtatt ttgcgattgg atcagagtgg agaaaaaacc ttgttcttgc gttccgctga
    13321 ctggtatacc caaaatagct ccttgtgtcc aattccaagt aatatgagca ccaatagccg
    13381 taaataaact tcctgtactg tagataagtg cgctgaaaaa gcaacctgct aaaaagatat
    13441 tgaaaactgc cagaaatgtc atgttaggat tcaatccgtg caaaagagca aataatgcag
    13501 cagatccaat cattgctatt aacggaccaa atctaagcat ctgatgctga aaaaagccac
    13561 ggaataaaag ctcttctgat gcccccactg caataaataa aataaaactc gttatcagcg
    13621 gcacaatgtt tgcgtttcct gaatctaacc gatacgcccc cgtcaaatat aatggactag
    13681 taataagcag aaacactcca attccaacaa cgagacctcc cgctaaatac ccccagtctt
    13741 ttcctcgaac agaaacacca taatcttcta ttctttttcc ttcgacctta ctagcaagaa
    13801 ataaagctag taaaaaaaca gctaaatgtc cgaccgtacc ggcaattgct ccaatccatt
    13861 cactatttcc aataaacata tccgcaagtg cattattgac aagaattcct aaaacaaaac
    13921 caactaagac tattaaaaca gatccaatca accgaataat cctgatcatc tttcatccct
    13981 cctttatatt aagtttaaca acccttttct ttcttgtctc gtgaaaacta tgtaaatgtt
    14041 ctccatcata gagagaatag atttttacga actaagaata tctacagcaa ccttacgaaa
    14101 atgaaagact gtctccctaa ttcttctgtt agactgtttt taataaggaa aggatgggaa
    14161 attttttgaa aaaacaacta ctaattatgt gcctttcagc atgtgcaatt ttactattct
    14221 caggttgtag caagtccaat gaaacgattg caacgtttaa aggtggaaca cttacagttc
    14281 aggattttta tgataaccca aaagttaaat caaataatca aacactatta aaaaaaatga
    14341 ttgtcttcaa agcatttgat gatgtatacg gaaaagagat ttcttcaaag gaagtaacaa
    14401 aagaatataa tgaacaaatc aaaaaactcg gtccaaacta caaggaacaa ttaaaagcag
    14461 ttggccaaac agaagagaca tataagaaac tctttaaaca gatgctggct ttccaatacg
    14521 gtttgaaagc caatgtaaaa ttaacagata aagatctaga cactgcttgg aaagaattct
    14581 atccagaagt tagtacacag atcattctat tttcgactaa agaagaagca gataaagcaa
    14641 aaaaagaagc aaatgaagga gaaaatttct ccaagcttgt tcaagcttat ggaaaaaata
    14701 aaacattaaa ggaaactgat ggaaaaatga attttgattc aaccaatcca gagattccta
    14761 ctgaagtaaa aaaagcagca tttaaactaa aaaacgggga agtttctgat atcattcctg
    14821 taacagatcc aacgacttat cagcaaagct attatctagt aaaaatggta aaaaaacagg
    14881 ataaaggttc taataaagac aaatacaaat ctgagctaga aaaaattgct accgaagcaa
    14941 aaactcttga tacggaattc atggataaaa caatccgtaa agtgatgaaa aaagacaatg
//
LOCUS       DAZKKZ010000064        14878 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.066, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000064 DAZKKZ010000000
VERSION     DAZKKZ010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14878)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14878)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14878
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.066"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..506)
                     /locus_tag="ACG8LA_002257"
     CDS             complement(<1..506)
                     /locus_tag="ACG8LA_002257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HFQ0204537.1"
                     /translation="MDNHTRKLLGLTDKHLFFDEEWLIEKEYKGVQAQFIKGKLDDSS
                     SYCEHCRSVRIIRNGSYTTRTQMLKVKEKLTILELKRTRFLCHDCGRTFSAKTDLVDE
                     HHQLTKELKQAILMELYENQSRKLIAKKYFVSDGTVTRILREATKHYQPRMNFLPTVL
                     CMDEFKSM"
     gene            779..3250
                     /locus_tag="ACG8LA_002258"
     CDS             779..3250
                     /locus_tag="ACG8LA_002258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HFQ0204538.1"
                     /translation="MKNKWINRSKKKKVTQRSSDKVIRLFPSYKEGLTADQVKERIEK
                     GAANNSVDPTFKTNQQIVLENIFTYFNLIFLILAILLCLVESYKNLTFLPVIIANTGI
                     AIFQEIRSKKILDELNVLNTAKVNVIRDGIEQTIDIEDLVIDDIVILETGYQIPADAE
                     VVEGKLQVNEALLTGEADEITKEIGDPLMSGSFIVSGKAYARLDKVGADSYISQLTVK
                     AKTMGEGEQSEMIASLNQLIKWIGIIIIPIGILLFSQSYFFNGNTIKESVVAMEAALI
                     GMIPEGLYLLTTIALALSATKLAKQRVLLHNMKSIETLARVNVLCVDKTGTITENKMS
                     VQKMIVSKKQEIISQSDQLEACIADYAKAMAGDNATMEAVKAYFTKTTDQSYHHVIPF
                     SSVQKFSSVALADKVYVLGAPEMVLRDQLPEYAEEFVSFAEKGYRVLVFGVYDGILEE
                     PVLTEAVTPLGYILIANPIRKEARATFDYFKKQQVAIKVISGDNPLTVSNVAVQAGIS
                     HADQYVDASKLSEEEYEAAVEKYTVFGRVKPEQKKIFVQLIKRNNTVAMTGDGVNDIL
                     AMKEADCSIAMASGNEAAMQASQVVLLDSDFSRMPEVVAEGRRVVNNIERSASLFLVK
                     NIFSFLLSLFSVIFALTYPLEPSQITLISLFTIGLPSFLLALEENKKRIRGKFIMNVM
                     EKAVPGGLTDMIVVGALVICGVTLNLNKTDVSTASTMLLIAVGFLVLYKICSPLNKFR
                     SQIILFCASGNFFSVIFLHKLFSITGISAVSLLLLSILFFSADSIFRHLTTLVEYLFE
                     RKNEKEQKPFSRVAKKFLSIFKREN"
     gene            complement(3353..5089)
                     /locus_tag="ACG8LA_002259"
     CDS             complement(3353..5089)
                     /locus_tag="ACG8LA_002259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFQ0204539.1"
                     /translation="MKWKKIYERLFFLILLVSLFFGGWQLISHYFQQQIVEQQESYLT
                     KKAQLLIRQLDVENLQAAQNKTALEEFVHQSNERITLMDATGKILFDTNNETLNEQRN
                     SRPEIKAVLNGGNLGSALRKSTTLNEDLLYVALPVKKSGQLEAILRIAEPTSVFLPRT
                     ESFRRWVFFFFLSFFLVLAGMIYYLIYQKNQPLKTVLPVLKKMVQNPNQAEVIMQTPD
                     QWEELYQTINALSEQMSKMYRACTTTEEQLYTLLNELMIGVFLIDDADSRLLLLNPKM
                     QLHLNVVSYQPEQRYTEVIQEPKLIQLIHQVTPEHPLIHQEITLTEGRQTLDLSLRYF
                     TNSEGTGQILGVAYDLTKVRRLEKLQKDFVGNVSHELKTPVTSLIGFTETLLDGAKDD
                     PQTLTSFLEIMQKDAIRLDKLIREIIQLSKDGENSYEIQTIYTEPYFQQIVQNYQPII
                     EKKRLTIRLIGKNEPFTTKTDILYPIIKNLIENAVQYSKSDSEIIIRYQATDDLSFSV
                     QDFGIGIDIEDQERIFERFYRVDKARSRHSGGTGLGLAIVKDYVQLLNGTITVDSHLG
                     TGSTFTVTIPKM"
     gene            complement(5086..5790)
                     /locus_tag="ACG8LA_002260"
     CDS             complement(5086..5790)
                     /locus_tag="ACG8LA_002260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFQ0204540.1"
                     /translation="MKKILVVDDEPSIVTLLTFNLEKEGYKVTSATDGGEGLELALEQ
                     SFDFIILDVMLPTMDGMEITQRLRQEKNETPILMLTAKDDQVDRIIGLEIGADDYLTK
                     PFSPREVLARMKAIFRRIEPRKQSKDEAEPEYLSIGQITADLTNYQVTVDDHLIELTP
                     KEFELLVYFMKRKDRVIDRDTLLDRIWNFDFAGQSRIVDVHVSHLREKIERDPKHPKY
                     LVTIRGFGYKFQEPKR"
     gene            5921..6424
                     /locus_tag="ACG8LA_002261"
     CDS             5921..6424
                     /locus_tag="ACG8LA_002261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HFQ0204541.1"
                     /translation="MIGISACLGGLACRYDGQKKEVPELMELVETGEAVMVCPEVIGG
                     LPIPRDPAEIIGGNGFDVWKDQAKVWTTSGEDVTEAYKNGAIKAYQKLQEKHIDLVIM
                     KEKSPSCGTHSIYDGSFSGIKKNGAGVATAYFIQQKMTVLSDEEWLKTRGEQNGNRKD
                     QSNERAL"
     gene            6384..6722
                     /locus_tag="ACG8LA_002262"
     CDS             6384..6722
                     /locus_tag="ACG8LA_002262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HFQ0204542.1"
                     /translation="MEIEKTNRMNALFEFYSTLLTEKQMNYMELYYADDFSLGEIAEE
                     YEVSRQAVYDNIKRTSKILEDYEKKLHLFSNYIVREQVLENMTAYITDKYPEDKKLLE
                     YVQQIQAIEE"
     gene            6743..8161
                     /gene="ffh"
                     /locus_tag="ACG8LA_002263"
     CDS             6743..8161
                     /gene="ffh"
                     /locus_tag="ACG8LA_002263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0048501 - signal recognition particle,
                     plasma membrane targeting [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005048 - signal sequence binding
                     [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HFQ0204543.1"
                     /translation="MAFESLTERLQQAMGKIRKKGKVSEADVKEMMREIRLALLEADV
                     NLQVVKDFTKRVRERAVGAEVLESLSPAQQIVKIVDEELTITLGSETAELNKSPKIPT
                     VIMMAGLQGAGKTTFTGKLANYLKKNENARPLLIAGDVYRPAAIDQLKVLGQQLDVPV
                     FDMGTEVSPVEIVRQGMELAKEKKNDYVLIDTAGRLHIDETLMDELKQIKELTQPNEI
                     LLVVDAMTGQDAVNVADSFNQQLGITGVVITKLDGDTRGGAALSIRSVTGAPIKFIGS
                     GEKLTDLEVFHPDRMASRILGMGDMLTLIEKAQQDYDEKKAEELAQKMRENSFDFNDF
                     IEQLDQVMGMGPLEDLIKMIPGMNQVPGIENVKVDPKDVERKKAMVYSMTPAERANPD
                     LLNPSRRRRIAAGSGNSVVEVNRMIKQFKESRKMMQQMSKGDMNIPGMDQMFGSGVKG
                     KLGKMAMNRMIKKNKKKKKKRK"
     gene            8273..8851
                     /locus_tag="ACG8LA_002264"
     CDS             8273..8851
                     /locus_tag="ACG8LA_002264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HFQ0204544.1"
                     /translation="MRCPWSEQTESMRQYHDTVWGVPEYDDQKLFRKLMLDINQAGLS
                     WQTILNKSEAFDEAYDRFDIKKVANYGETKISELMENKGIIRNRRKIEAAVQNAKAVL
                     KIQEEIGSFSEYLWSFSNGKIVDSSYHSQEEVPTTSPLSDELAKDLKKRGFKFIGSTT
                     IYAFLEAVGIINDHLDSCFRKEEVVRIGRKGE"
     gene            8803..9375
                     /locus_tag="ACG8LA_002265"
     CDS             8803..9375
                     /locus_tag="ACG8LA_002265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase family protein"
                     /protein_id="HFQ0204545.1"
                     /translation="MFPQRRGRTYRQKGRIKHAKIIFYGAISLDGYLATKTDDLQWLF
                     DTPTGKQTTYEAFYETIDTTIMGRKTYQEAKKYLETEAIYPEKKNFVFSTHAQLQLPD
                     AEVVNEDPVAFLKNLQMTEGKDIWVVGGGRLIKPLLEHQMIDEWYIQITPVLLGDGIP
                     LFQKGTYEARFEMLDTTRFGEFIELHYVRK"
     gene            complement(9454..10008)
                     /locus_tag="ACG8LA_002266"
     CDS             complement(9454..10008)
                     /locus_tag="ACG8LA_002266"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008752 - FMN reductase (NAD(P)H) activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0052873 - FMN reductase (NADPH) activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent FMN reductase"
                     /protein_id="HFQ0204546.1"
                     /translation="MTKKIGFFIGSLRKDSYNKKVAEAFAKLLPEGYESVFVKIDDLP
                     FYNEDLETPEQAPAEWTRFREEVRGLDGVVFVTPEYNRSVPAVLKNALDVGSRPYGHS
                     VWDHKPGLVVTASPGGIGGFGANHHLRQSLVFLNVPTLQQPEAYIGNVANLIDENGNI
                     VEGTLSFFQTILDAYLDFSNKLTE"
     gene            10261..10536
                     /gene="rpsP"
                     /locus_tag="ACG8LA_002267"
     CDS             10261..10536
                     /gene="rpsP"
                     /locus_tag="ACG8LA_002267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HFQ0204547.1"
                     /translation="MAVKIRLKRMGSKKSPFYRIVVADSRSPRDGRFIETVGTYNPLK
                     DPAEVVLKEDLVLDWLSKGAQPSDTVRNILSKEGVMQKHHEAKFSKK"
     gene            10548..10799
                     /locus_tag="ACG8LA_002268"
     CDS             10548..10799
                     /locus_tag="ACG8LA_002268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HFQ0204548.1"
                     /translation="MKDLSDLVLTIVRPLVTYPDQVKLDVVESKDFYEYNLTVAPEDI
                     GRIIGKQGRVAKAIRTIVYGVRINAPKKVRLNIIDDKEK"
     gene            10924..11715
                     /locus_tag="ACG8LA_002269"
     CDS             10924..11715
                     /locus_tag="ACG8LA_002269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204549.1"
                     /translation="MRKKMLFIPFALLLSACSSVTQESDNTHLSSSISETVTSPEKSS
                     TKTASTTEQTMATSNNEKKTALDQLKEQQPNVPMPLDVPVSSGYLNIAATHTKQGYSI
                     LYYRTDRPLGLNADELNQETPIATYLYQYGFASSQETIQVLQPFEIDTNGQQVDLGSR
                     ITGYQQGAAGSSFLEWQEGNWRIRIRGNNIEGQDPLLLAKEIVAYLEENSLPAPEQFG
                     KITVDMGDTTNRAVEVSWQEPKNAYTITHQDPMSALKMAVSMKRL"
     gene            11885..12406
                     /gene="rimM"
                     /locus_tag="ACG8LA_002270"
     CDS             11885..12406
                     /gene="rimM"
                     /locus_tag="ACG8LA_002270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319275.1"
                     /note="Essential for efficient processing of 16S rRNA;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HFQ0204550.1"
                     /translation="MTEYLNVGKIVNTQGIKGEVRVISTTDFPEERYKKGTVLTLFQD
                     GKAPVELTVKSHRKHKNFDLLSFEGHPSINDVEKYRDGILKVSKDNSVDLAENEFYYH
                     EIIGLHVLEDGTELGKVKEILSPGANDVWVVQRPKKADILLPYIASVVKEVDLEAGVV
                     RVEIPEGLIDDED"
     gene            12396..13157
                     /gene="trmD"
                     /locus_tag="ACG8LA_002271"
     CDS             12396..13157
                     /gene="trmD"
                     /locus_tag="ACG8LA_002271"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052906 - tRNA
                     (guanine(37)-N1)-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HFQ0204551.1"
                     /translation="MKIDVLTLFPRMFEGPMGESIIGKAVDKGLLDINISNFRDYSDN
                     KHQTVDDYPYGGGAGMLLKVQPIYDNIQAIEKAAPDVKKRVILLDPAGKRFDQKMAEE
                     FSQEEHLVFICGHYEGYDERIRTLVTDEVSLGDYVLTGGELGAMVMIDATVRLLPDVL
                     GNQTSAQTDSYSTGLLEHPQYTRPAEYKGMKVPEVLTNGNHKLIEEWQLKESLRRTYQ
                     RRPDLLETLEWTPQMTKFLEEIKKEEQEKTADEAK"
     gene            13293..13640
                     /gene="rplS"
                     /locus_tag="ACG8LA_002272"
     CDS             13293..13640
                     /gene="rplS"
                     /locus_tag="ACG8LA_002272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000311 - plastid large ribosomal subunit
                     [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HFQ0204552.1"
                     /translation="MNPLIEELTKEQLRSDIPAFRPGDTVRVHAKVVEGTRERIQLFE
                     GVVIKRRGAGISETYTVRKVSNGVGVERTFPLHTPRVAKIEVVRYGKVRRAKLYYLRA
                     LHGKAARIKEIRR"
     gene            complement(13676..13861)
                     /locus_tag="ACG8LA_002273"
     CDS             complement(13676..13861)
                     /locus_tag="ACG8LA_002273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204553.1"
                     /translation="MLEYSGFFIKAVTLKKDIIIVLFFLLLLIGRFILIHYSPLPIIK
                     EKTGSGCSNYMLRKKNP"
     gene            13898..14191
                     /locus_tag="ACG8LA_002274"
     CDS             13898..14191
                     /locus_tag="ACG8LA_002274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2087 domain-containing protein"
                     /protein_id="HFQ0204554.1"
                     /translation="MVYTYTEQEKMKVLDTFMNDGKVKQVPSSTKKKYILLKEVLKRF
                     DHGVTYTETEVNSILLNVFSSGDYVEQRRYLITFGFFKRSSDGRAYQMMGIEN"
     gene            complement(14279..14425)
                     /locus_tag="ACG8LA_002275"
                     /pseudo
     CDS             complement(14279..14425)
                     /locus_tag="ACG8LA_002275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332517.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane glutamate
                     endopeptidase"
BASE COUNT         4945 a         2691 c         3017 g         4225 t
ORIGIN      
        1 ttcattgatt tgaactcatc catacacaac accgtcggaa ggaagttcat acgtggctgg
       61 taatgcttcg ttgcttcacg caagatccgt gtcaccgtcc catccgagac gaagtacttc
      121 ttagcgatta gtttacgtga ttgattttcg tacagttcca tgagaatcgc ctgcttcagt
      181 tcctttgtta gttgatgatg ttcatcaact aagtccgttt tcgcagaaaa ggtccttcca
      241 caatcatggc agagaaaacg ggtacgtttt aattctaaaa tagttaactt ttctttgact
      301 ttcaacatct gagtgcgtgt cgtataggaa ccgttgcgga taatacgaac cgatcgacag
      361 tgttcacaat aggaagaaga gtcatccaat tttcctttaa taaactgcgc ttgaacgcct
      421 ttatattctt tttcaatcag ccattcttca tcaaaaaata aatgtttatc tgttaatccg
      481 agtaattttc tagtatgatt atccattgag agactccttt ggtaggatga cgttttggtc
      541 gactaaattt taccaaaagt gagtctcttt ttgagttgaa acgaagaaaa agtgttagta
      601 gaaaatcgcc ttcgattttc caccaacaca aaatattata gaaccctttt tttttgctat
      661 atgacaggaa tgaaaggtgt ttgcaagctt aatgtgagga acactttcca tatctgttct
      721 atactggata ggagaagttt ggaaatatcc agaaaacgaa atcaatcgag gtagccacat
      781 gaagaataaa tggataaatc gaagtaaaaa aaagaaagta acacaaagat catcagataa
      841 agtcatccgt ctttttccat cgtataaaga aggattaacg gcagatcaag tcaaggaacg
      901 aatagaaaaa ggtgcagcaa ataattcagt cgatcccaca ttcaaaacaa atcagcaaat
      961 cgtattggaa aacatattta cgtatttcaa tttgatcttt cttatcttag ccattttgct
     1021 ttgtttagta gaatcctata agaacttgac ttttttacca gttatcatag ccaatacagg
     1081 aatcgccatt tttcaggaaa ttcgatccaa aaagatcttg gacgaactaa atgttttaaa
     1141 tacagcaaaa gtcaatgtca tacgagacgg gatagaacaa acaatagata tagaagacct
     1201 tgtaatagat gacattgtta ttttagagac tggatatcaa attccagcag atgcagaggt
     1261 cgtggaaggg aaactgcaag ttaatgaggc tttattgaca ggcgaagcag atgaaataac
     1321 caaagaaata ggtgatccat taatgtccgg cagtttcatt gtttccggaa aagcttacgc
     1381 ccgattagac aaagttggag cagattcgta tatttcccag ctgacagtca aagccaagac
     1441 aatgggagaa ggagaacagt cggagatgat tgcttctctt aatcaattga tcaaatggat
     1501 tgggatcatc attattccta tcggtatcct gcttttttct caaagttact tttttaatgg
     1561 aaacacgatc aaagaaagtg tcgttgcaat ggaagcagca ttgatcggta tgatacctga
     1621 aggactgtac ttgctgacga cgattgcatt agcattaagt gcgactaaac tagcaaagca
     1681 aagagttctt ttacacaata tgaaaagcat tgagacattg gcaagggtaa atgtcctttg
     1741 tgtagataaa acaggaacga tcacagaaaa taaaatgtct gttcaaaaaa tgatcgtctc
     1801 taaaaaacaa gaaataatca gtcagtcaga tcaattggaa gcatgcattg ctgactatgc
     1861 aaaagcgatg gcaggagaca atgcaacaat ggaagctgtt aaagcatatt ttacaaaaac
     1921 cactgatcaa tcctatcacc atgttattcc tttttcttct gtccaaaaat tcagcagtgt
     1981 agcgttggca gacaaggtgt atgttttagg agcgcccgaa atggttttgc gcgatcaatt
     2041 gccggaatat gcggaagagt ttgtttcttt cgctgaaaaa ggctatcgcg tgttggtctt
     2101 tggtgtgtac gatgggattc ttgaagaacc agtattgaca gaagcagtca caccattagg
     2161 ctatattctg attgctaatc ctatcagaaa agaagcaaga gccacatttg attacttcaa
     2221 aaaacagcaa gtagccatca aagtgatttc tggagataat ccgctcaccg tatccaatgt
     2281 agctgtccaa gcagggattt cacatgctga tcagtacgtt gatgcatcta aattatcaga
     2341 agaagaatat gaagcagctg tcgaaaaata tacagttttt ggacgcgtca agccagaaca
     2401 aaagaaaatc ttcgttcaat tgataaagcg taacaataca gtagctatga caggtgatgg
     2461 cgtgaatgat attctagcca tgaaagaagc agactgcagt atagcgatgg cttccggaaa
     2521 tgaagccgcc atgcaggcct cacaagtggt cttacttgat tctgactttt cacgcatgcc
     2581 agaagttgtt gcagaaggac ggcgcgttgt gaacaatatt gagcgatcag ccagcttgtt
     2641 tttagtgaag aatattttct cctttttgct ctcactgttt tcagtgatct ttgctctgac
     2701 ctatccttta gaaccatcac aaatcacatt gattagtttg tttactatcg gacttccatc
     2761 tttcttgctt gctctagaag aaaacaaaaa gcgaatcaga gggaaattca tcatgaatgt
     2821 gatggaaaaa gctgtgccag gtggactaac agatatgatc gtagtcggtg cgttggtgat
     2881 ctgcggggtg actttgaatc taaataaaac agatgtttct acagcatcta ccatgctttt
     2941 gattgcagta gggttcctcg ttctctataa aatctgttca ccgctgaata aattcagaag
     3001 tcagatcatt cttttctgtg ctagcggtaa ctttttttcg gtcatctttt tgcataagct
     3061 gttttcaatc accggtatct cagctgtatc acttttgctg ttgagcattc tatttttctc
     3121 ggcagattcg atttttaggc atttgaccac attggtagaa tatttgtttg aacgtaaaaa
     3181 tgaaaaagag caaaagccgt ttagtcgcgt agctaaaaaa tttctatcga tatttaaacg
     3241 agaaaattga cgaaaagtat ctcaaaaaag agtaaaaaag aacaaccact cgtgtatctt
     3301 tcgaagcagg atgagtcatc caactttaaa acgcacgagc agttgctctt ttttacattt
     3361 tcggaatggt aacggtgaaa gtcgaacctg ttccaagatg actgtctaca gtaatcgtac
     3421 cattaaggag ttgcacgtag tcttttacaa tcgctaaccc taatccggtc ccgcctgaat
     3481 gtcggcttcg cgccttgtct acgcggtaaa aacgctcaaa gatccgttcc tgatcctcaa
     3541 tgtcgatacc tataccaaag tcttggacag aaaacgatag atcatctgtt gcctgatagc
     3601 ggataataat ctcgctgtcg ctttttgaat attggacagc attttcaatc agatttttga
     3661 taattggata aaggatatct gttttagtag taaatggttc gttctttcca atcaatcgaa
     3721 tcgtcaaccg tttcttttcg atgattggct gataattttg aacgatttgc tggaaataag
     3781 gttctgtata aattgtctgg atctcgtaag aattctcgcc atcttttgac agctggatga
     3841 tttcccgaat cagtttatct aaccggatcg catctttttg catgatctca agaaaagaag
     3901 tcagagtttg cgggtcatct tttgcaccat ccagtaaagt ctcggtaaaa ccaatcagtg
     3961 aagtcacagg agtttttaat tcgtgagaga cgttgccaac gaaatccttt tgtagctttt
     4021 ctaaacgtcg cactttcgtt aagtcatacg ccacccctag aatctgtccg gtaccttctg
     4081 aattagtaaa gtagcgcaaa ctcaagtcta atgtctgccg accttctgta agggtgatct
     4141 cctgatggat cagcggatgc tcaggagtca cttgatgaat cagctgaatg agttttggct
     4201 cttgaatgac ttctgtgtac cgctgttcag gttgatagct taccacgttt aaatgtagct
     4261 gcatctttgg attaagcagt agtaaacgag aatcagcatc atcaatcagg aatacgccaa
     4321 tcatcagttc gttcagtaac gtatataatt gctcttctgt ggtagtacac gcccgataca
     4381 tcttactcat ttgttcgctc aacgcattaa tcgtctgata caattcttcc cattgatcgg
     4441 gtgtttgcat gattacttcc gcctgattag gattttgcac catttttttt agtacgggca
     4501 gcacggtttt caatggctgg tttttttgat agatcagata atagatcatt cctgcaagaa
     4561 caaggaagaa agacagaaag aagaaaaaga cccaacggcg aaaactctca gttctcggta
     4621 aaaaaacgct tgtcggttct gcgatacgta aaatggcttc taactggcca ctttttttga
     4681 ctggtaatgc gacatataaa agatcctcat tcaaagtagt acttttgcgc aaagcgctac
     4741 ctaggttccc accattcaat acggctttga tttcgggacg ggagtttcgc tgttcattca
     4801 atgtttcatt gtttgtgtca aataagatct ttccagtagc atccattaaa gtaatccgtt
     4861 cgttcgactg atggacgaat tcttccaaag cagttttgtt ttgcgctgct tggaggtttt
     4921 cgacatctaa ttgccggatc agcagttgtg ctttttttgt caggtagctt tcttgctgtt
     4981 ccacgatctg ctgttgaaaa taatgggaaa tcaattgcca gccaccaaaa aacaaactaa
     5041 ctaaaagaat aagaaagaag agacgttcat aaattttttt ccatttcatc gtttgggttc
     5101 ctgaaactta tagccaaatc ctctaatagt caccaagtac tttgggtgtt ttggatctcg
     5161 ctcgattttt tctcgcaaat gactaacgtg tacatctacg attcggcttt gtcctgcgaa
     5221 gtcaaaattc caaatgcggt ctagcaatgt gtctcggtcg atcacacggt cttttcgttt
     5281 catgaaataa acaagtaatt caaattcttt cggtgttagt tcaatcagat ggtcgtctac
     5341 ggtcacttga taattggtca aatcagcagt gatttgtcca atcgatagat attcaggctc
     5401 agcttcatct tttgattgct tacgaggttc aattcgtctg aatattgctt tcatacgggc
     5461 taatacttcg cgaggactaa atggtttggt caaatagtcg tcagcaccta tttctaggcc
     5521 aatgatccga tccacttggt catctttagc cgtcagcatc aaaatcggtg tttcattttt
     5581 ttcttgacgc agccgctgag tgatctccat gccatccatc gttggaagca tcacatctaa
     5641 aatgatgaaa tcaaatgatt gttctaatgc taattctaat ccttcgcctc catctgtggc
     5701 actggttacc ttgtagcctt ctttttccaa attgaacgtc aagagcgtta caatagaagg
     5761 ttcatcatca acaactagta tttttttcat tcaaatctcc tttaaatagg tttcattctg
     5821 tttatatttt agcatagaat cagtacaaag ggctatttta caaaagaaat aaatggtata
     5881 ataggaaggc actttgctga atagaaagga agagcagtca atgattggaa tcagtgcatg
     5941 tttaggcggt ctggcctgtc gctatgatgg acagaaaaaa gaagtaccag aattgatgga
     6001 actagttgaa actggagaag ctgtcatggt ctgtccagaa gtgatcggcg gattaccaat
     6061 tcctagagat cccgctgaaa tcattggtgg aaatggattc gatgtgtgga aagatcaagc
     6121 aaaagtatgg acgacaagcg gcgaagatgt aacggaagcg tacaaaaatg gcgcgatcaa
     6181 agcctatcaa aaattgcagg aaaaacacat tgatctagtc atcatgaagg aaaaaagccc
     6241 ttcatgcgga acccattcga tttatgacgg aagtttttcc ggaataaaaa aaaatggtgc
     6301 cggagtggct actgcttatt ttattcagca aaaaatgact gtgctctctg atgaagaatg
     6361 gctgaaaact agaggtgagc agaatggaaa tcgaaaagac caatcgaatg aacgcgctct
     6421 ttgaatttta ttcgacctta ttgacagaaa aacaaatgaa ctacatggaa ttatattatg
     6481 cagatgattt ttcattaggt gagatcgcgg aagaatacga agtaagccga caagcagtat
     6541 atgacaatat caagcggaca agcaagatct tggaggatta tgaaaaaaaa ctccatcttt
     6601 tttctaatta tattgttcga gaacaggtat tggaaaatat gactgcatat attacagata
     6661 agtacccgga agataaaaaa ctacttgaat atgtacagca aattcaagca atcgaagaat
     6721 aaataaaagg aatgaagaaa atatggcatt tgaaagctta actgaacgtc tccagcaggc
     6781 gatgggaaaa ataagaaaaa aaggaaaagt atcagaagct gacgtaaaag aaatgatgcg
     6841 ggaaatccgc cttgccttac tagaagccga tgttaacttg caagtagtca aagattttac
     6901 taagcgcgta cgcgaacgtg cggtaggggc agaagtgctg gaaagtttat cacctgcaca
     6961 acaaatcgta aaaatcgttg atgaagaatt gacgatcaca cttggttctg aaacagcaga
     7021 gttaaataaa tcaccaaaaa taccaactgt tatcatgatg gctggtcttc aaggggcagg
     7081 taaaacgacc tttactggta aattagccaa ttatttaaag aaaaatgaaa atgctcgtcc
     7141 gctcctaatc gcaggggacg tatatcgacc agctgcgatc gaccaattga aagtattagg
     7201 tcaacagcta gacgttcctg tatttgatat gggaactgaa gtcagcccgg tagagatcgt
     7261 ccgtcaaggg atggagttag caaaagaaaa gaaaaacgac tatgtattga tcgatacggc
     7321 aggacgtctg catatcgatg aaacattgat ggatgagttg aaacaaatca aagaattgac
     7381 gcaaccaaat gagattttgc ttgttgtcga tgccatgact ggtcaagatg ccgtcaacgt
     7441 agctgatagc ttcaaccagc aattaggtat tacaggggtc gtcatcacta aacttgatgg
     7501 ggatactcga ggcggggcag cactatcgat ccgctcagtg acaggcgcac caatcaaatt
     7561 catcggttct ggtgaaaaat tgactgactt agaagtattc cacccagatc gtatggctag
     7621 ccgtatcctt ggtatggggg atatgctgac attgattgaa aaagcgcagc aagactatga
     7681 cgagaaaaaa gcggaagaac ttgcacagaa aatgcgggaa aattcattcg atttcaatga
     7741 ctttattgaa cagcttgatc aagtgatggg tatgggccca ctggaagatc taatcaaaat
     7801 gatcccagga atgaatcaag tccctggaat cgaaaacgtc aaggtagatc caaaagatgt
     7861 tgaacgcaaa aaagcgatgg tttattctat gacgccagca gaaagagcaa atcctgatct
     7921 gttgaaccca agccgtcgtc gccgaattgc tgccggttct ggaaacagtg ttgttgaagt
     7981 gaatcgaatg atcaaacaat tcaaggaatc aagaaaaatg atgcagcaaa tgtccaaagg
     8041 ggatatgaac atcccaggta tggaccaaat gtttggttca ggcgtcaaag gaaaactagg
     8101 caaaatggcg atgaatcgaa tgatcaagaa aaataagaag aaaaagaaaa aacggaaata
     8161 agatgaaaaa aacagcttcg gtacagactg aaaatgtcta ctgccggagc ttttctatca
     8221 gcaattttta ttctttacta atacaattac tctaaacgaa gaggtggcac agatgagatg
     8281 tccgtggagt gaacaaacag aaagtatgcg gcaatatcat gatactgtct ggggtgttcc
     8341 tgaatatgat gaccaaaagc tgttccgaaa attgatgctt gatattaatc aagccggatt
     8401 gagctggcag acgattttaa ataaaagtga agcattcgat gaagcatatg atcgattcga
     8461 tattaaaaaa gtcgcaaatt atggagaaac aaaaatcagt gaactaatgg aaaacaaagg
     8521 aattattcgt aaccgaagaa aaatcgaagc agccgtccaa aacgccaaag cagtcttgaa
     8581 aattcaagaa gaaatcggca gtttttcaga gtatctttgg tcgttttcta atggaaaaat
     8641 cgttgattct tcttatcatt cacaagaaga agtcccaaca acaagtcctc tttcagatga
     8701 attagcaaaa gatctaaaga aaagaggatt taaatttatc ggaagcacaa caatctatgc
     8761 ttttttagaa gctgtcggga tcatcaatga tcaccttgac agttgtttcc gcaaagaaga
     8821 ggtcgtacgt atcggcagaa agggcgaata aagcatgcga aaatcatatt ttatggtgct
     8881 ataagtttag atggctattt ggcaacgaaa acggatgatc ttcaatggct ttttgacact
     8941 ccaacaggta agcaaaccac ttatgaagct ttttatgaaa caatcgatac gaccatcatg
     9001 ggcagaaaaa cttatcagga agcaaaaaaa tatttggaga ccgaagcaat ttatccagag
     9061 aaaaagaatt tcgttttttc cacccacgca caattacaat tgccagatgc tgaggtcgta
     9121 aacgaagatc ctgttgcttt tctaaaaaat ctacaaatga cagaaggaaa agatatctgg
     9181 gttgtgggtg gcggtcgatt gatcaaaccg ctattggaac atcaaatgat tgatgaatgg
     9241 tatatccaga ttacccctgt attattaggg gacgggattc ctttattcca aaaaggaaca
     9301 tatgaagcgc gttttgaaat gctagacacg acacgattcg gtgaatttat cgaattgcat
     9361 tatgtacgaa agtagaagta aataaaataa aaaaggcaac tatatgcaga aatgtcctgt
     9421 acatagttgc cttttttatt accgttatgc tttttactct gttaatttgt tagaaaaatc
     9481 tagatacgca tctaaaatcg tttggaagaa acttaatgtt ccttcaacga tattaccatt
     9541 ttcatcaatt agattcgcaa cgtttccgat atatgcttcc ggttgctgca aggttggcac
     9601 attcaaaaag acaagtgatt ggcgtagatg gtggtttgcg ccaaagccgc cgatcccacc
     9661 tggtgatgca gtaacgacta aacctggttt atgatcccaa acactgtgtc cataaggtct
     9721 tgagcctaca tctaaagcat ttttcaatac tgctggcaca gaacggttgt attcaggagt
     9781 aacgaaaacg acaccgtcta gtcccctcac ttcctcacga aaacgagtcc attcagcagg
     9841 agcctgttct ggagtttcga gatcctcatt gtaaaatggc agatcatcga tttttacaaa
     9901 tacactttcg tacccttcag gaagcaattt cgcaaaagct tctgctactt ttttgttgta
     9961 agaatctttt cttaaactac caataaaaaa tccaattttt tttgtcatac gatttttcct
    10021 ccttcaaact atctataata atcttacaaa agataagtaa ctggagcaaa taaaaacact
    10081 tactgacaaa agctacatag aagatagatt acttattttt aacaaaaaag aagtctaaaa
    10141 tcttctattt tctaaaaaaa atcgaattta atcaagctgt aaagaaaaaa agctttacag
    10201 ggtaaaaaaa aactgttaca ctacatcttg tgaataaaac aatggaggtg gaaataaata
    10261 atggcagtta aaatccgttt aaaacgtatg ggttctaaaa agagtccgtt ttaccgtatc
    10321 gtcgtagctg attcacgttc tcctcgtgat ggacgtttca tcgaaactgt aggtacttac
    10381 aatcctttga aagaccctgc agaagtagtt ttaaaagaag acttagttct tgactggtta
    10441 tcaaaaggtg cacaaccttc tgacactgta cgtaacatcc tttcaaaaga aggcgttatg
    10501 caaaaacacc acgaagctaa attctcaaag aaataaggtg accggatatg aaagatttaa
    10561 gcgacttagt cttaacaatc gttcgtccgc tagtcactta tcctgatcaa gtcaagttag
    10621 acgtcgtaga gtcgaaagac ttttacgagt acaatctaac agtggctcct gaagatattg
    10681 gccgtatcat tggaaaacaa gggcgtgttg ctaaagcaat ccgcacaatc gtttacggtg
    10741 ttcggatcaa tgcaccgaaa aaagtgcgtt tgaatatcat cgatgataag gaaaagtaaa
    10801 taaacgtgct gtactcgaat tttcgagtgc agcttttttg ttttttttat taattgaaga
    10861 aatgattatt tggcaaaaca agcaagaaag cgtatcctta taggaggagg gagtgaacag
    10921 ccaatgagaa agaaaatgtt atttattcca tttgctctat tgttaagcgc ttgtagttcg
    10981 gttactcaag aatcagacaa tacacatcta tcaagcagta tatctgaaac tgttaccagt
    11041 ccagaaaaaa gtagtaccaa aacggcttcc accactgaac aaacaatggc tacctcaaat
    11101 aatgagaaaa agactgcttt agaccagttg aaagaacaac agccaaatgt tcccatgcct
    11161 ctagatgtac cagtctcttc aggctatctc aatatcgcag cgacacatac aaagcaaggt
    11221 tattctattt tatattacag aacagatcgt cccctcgggt tgaatgctga cgaattgaat
    11281 caagaaacgc ctattgcaac ctatctatat caatatgggt ttgcttctag tcaagaaaca
    11341 atccaagttt tgcagccatt tgagatcgac acaaatggtc agcaagtgga cttaggttct
    11401 cgaatcacag ggtatcagca aggtgcagca ggttcaagtt ttcttgaatg gcaagaagga
    11461 aactggcgta ttcgaatccg tgggaataat atagaaggcc aagatccctt actattagct
    11521 aaagaaatcg tagcttattt ggaagaaaac agtctaccag cacctgaaca atttggtaaa
    11581 attactgttg atatgggtga tacgacgaat cgagccgtag aagtaagctg gcaagaaccg
    11641 aaaaatgcct atacgatcac tcatcaagat cctatgtctg cgttgaagat ggcagtttct
    11701 atgaagaggt tgtgaaatca gcgcgctgat ctgagcccat catttaactc caagtcacag
    11761 gaagtaatca aaaatagcac gccgcatttt tgcataattt tggcttaata ccttaaaaga
    11821 aaactagaat tgcctcttca cacatgctaa aataaaacag acaaaaaaga aatggggata
    11881 taagttgact gaatacttga atgtaggaaa aatcgtaaac acacaaggta tcaaaggcga
    11941 agtccgtgtt atctcaacaa cggatttccc agaagaacgt tacaaaaaag gaacggtgct
    12001 aacactattc caagacggaa aagcacctgt ggaattaaca gtcaaaagtc atcgcaaaca
    12061 taaaaatttt gacttattga gttttgaagg acatccttct atcaatgatg tggaaaaata
    12121 tcgggatggc atattaaaag tgtcaaaaga caactctgta gatctagctg aaaatgaatt
    12181 ctattaccat gagatcatcg gtctgcatgt attagaagat ggaactgagt taggtaaagt
    12241 aaaagaaatc ttgtcaccag gtgccaatga tgtttgggtc gttcaacgtc cgaaaaaagc
    12301 tgatatattg cttccatata tcgcttctgt cgtcaaagaa gtcgatttag aagctggagt
    12361 ggtccgtgta gaaattccag aaggactgat tgacgatgaa gattgatgta ttgactttat
    12421 ttccaagaat gtttgaaggt cctatggggg aatccatcat cggtaaggct gtagataaag
    12481 gattattaga tatcaatatc tctaacttcc gcgattattc agataacaaa catcagacag
    12541 tagatgatta tccatacggc ggtggagcag gtatgctgct caaagtccag cccatctatg
    12601 ataacatcca agccattgaa aaagctgcac cggatgtcaa aaaaagagta attcttcttg
    12661 acccagctgg taaacgattc gatcagaaaa tggcagaaga attttcacaa gaagaacact
    12721 tagtattcat ttgtggtcat tatgagggat atgatgaacg tatccgcaca ttagtgacag
    12781 atgaagtttc cttaggagat tatgtcctta ctgggggaga attaggtgcg atggtcatga
    12841 tcgatgcaac agttcggctt ttgccagatg tgttagggaa tcagacttca gctcaaacgg
    12901 attcttattc aaccggttta ttggaacatc cccaatatac tcgcccggca gaatataaag
    12961 ggatgaaagt accagaagta ttgacaaatg gaaatcataa attgattgaa gaatggcaat
    13021 taaaagaatc actaagaagg acctatcaac gtcggcctga tcttttggaa acacttgaat
    13081 ggacacctca aatgacgaaa tttttagaag aaatcaagaa agaagaacaa gaaaaaacag
    13141 cagatgaagc caagtgactt tttctaaaat cttctttaca gtaggttgat aatatgttag
    13201 tattttatgg tgagtgcaaa agcacttaac tattacgata ttccgctgtg agaaaagctc
    13261 ataagaatat ttggaataag gagaagaaaa ccatgaatcc attaatcgaa gaattaacaa
    13321 aagaacaatt acgttctgac atcccagcgt tccgccctgg tgacactgtg cgtgttcacg
    13381 caaaagttgt tgaaggtact cgtgaacgta tccagttatt tgaaggtgtt gttatcaaac
    13441 gccgcggtgc tggaatcagc gaaacttata cagtacgtaa agtttctaac ggagtgggcg
    13501 ttgaacgtac attcccattg catacaccac gtgttgcaaa aatcgaagta gttcgctacg
    13561 gtaaagtacg tcgtgcaaaa ttgtactacc tacgtgcatt acacggaaaa gctgctcgta
    13621 tcaaagaaat ccgtcgttaa tcattgttat cagactgaga aagaaccctt ggtattcaag
    13681 ggttcttttt tcttagcatg taatttgaac accctgatcc agttttttct ttaattattg
    13741 gtaggggaga ataatggatt agaataaatc tacctataag tagtagtaaa aaaaagagca
    13801 ctatgataat atctttctta agagtaaccg ctttaataaa aaatccagaa tattctaaca
    13861 taaatggagt attcttagaa tcaaaaggag aaagaagatg gtttatactt atacggagca
    13921 agaaaagatg aaagttttag acacattcat gaatgatgga aaagtaaaac aagtaccaag
    13981 ttcaacaaaa aagaaataca tcctattgaa agaagtcttg aaacgctttg accatggagt
    14041 gacttataca gaaacagagg ttaattcgat actgctgaac gtattttcta gtggcgatta
    14101 tgtcgaacaa agacgttatc taatcacatt tggctttttc aaaagaagtt cagacggtcg
    14161 ggcatatcag atgatgggaa ttgaaaatta gaagttttaa tttatactca ttgaaaaaag
    14221 ttcaagtatg cgatattggt tctacaccgc atacttgaac tttttttgtc atctgtatct
    14281 ataatacaaa gccaagaacg ttattcaaaa tatggatagc tatgataaaa gctaatgagc
    14341 gattcgcagt taaataagca atcgtcagta aaatcgttcc aggagcgtac atgaaaaaat
    14401 caattggatg cgttacatga ataaagataa ttctctttta tttgtacgaa taaataccaa
    14461 aacgtacctc ctaaaattag attttggaca gatgcccttt aaaaagataa caagatttcg
    14521 ttcttgaaac aatatatatg cttttattcc aatgaggttg tgaaaacagt attttgtcct
    14581 gagcgttaga aaattgaaaa tggggaatag caactcgtac tttaccattt tttaagtgaa
    14641 tacaagatca gctaattgaa caccgtttat tcgtgatgag ggacacaaca ctgcagtcga
    14701 cacatttctc ttttatgttc aaagataaca aatatttaaa acaaagaaaa atagtagata
    14761 atcccgtcct aactctttta ttcttccctc atagcttcca aatttaagca atacttcaat
    14821 taatcaagtt ttatcttttt ttttcaataa tcgtaaaaaa agagtatttt ttatttaa
//
LOCUS       DAZKKZ010000065        14347 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.067, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000065 DAZKKZ010000000
VERSION     DAZKKZ010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14347)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14347)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14347
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.067"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            476..1339
                     /locus_tag="ACG8LA_002276"
     CDS             476..1339
                     /locus_tag="ACG8LA_002276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HFQ0204555.1"
                     /translation="MYQIVTDSCCDLPYHVLAKEKVDFLSMNLQLNDQELVDDLGKTF
                     NYDRYMNQLKNGAMPTTSQINVGRYLEFFRSYAEKQIPVLYVAFSSGLSGSYSSALQA
                     VELLKEEYEDPEIYVFDTKAASIGEGLLVLEAVRLKKEGKSIEETLEWLESNYLKVHS
                     WVTVDDLKYLERGGRISKASATLGSLLSVKPIITVDKEGRLTNVDKVRGRNKSIQTIV
                     NETVKTIVAPLDQIVYVAYAGDLESAEKAKRLLEEQIKMKDVKLYPLGPTIASHTGYG
                     CIAIFSMGISR"
     gene            complement(1468..3090)
                     /locus_tag="ACG8LA_002277"
     CDS             complement(1468..3090)
                     /locus_tag="ACG8LA_002277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HFQ0204556.1"
                     /translation="MITVNDVSLHFSDRKLFDDVNIKFTPGNCYGLIGANGAGKSTFL
                     KVLSGDLQPSTGSVTMGPDERMAVLKQNHYDYEDYTVLETVIMGHKRLYEVLKEKDAI
                     YMKEDFTDEDGIRAAELEGEFAELNGWEAEPEAAVLLQGLNIPEELHHQQMSELTGGQ
                     KVKVLLAQTLFGKPDVLLLDEPTNGLDIQSINWLEEFLINFENTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWLESSQLAAKLQANANAKKEEQIKELQEFIARFSANA
                     SKSKQATSRKKMLEKITLDDIQPSSRRYPFVGFKPEREIGNDLLQVENVSVTIDGKKI
                     LDDISFNLSKEDKVAFVAENDITTTTLFKVIMGEITPDTGTVRWGVTTSNSYLPKDTT
                     KEFDTDLTILDWLRQYASKEEDDNTFLRSFLGRMLFSGEEVLKPVNVLSGGEKVRCML
                     SKMMLSKANVLVLDDPTNHLDLESITALNDGLMAFTGSILFASHDHQFIQTLANRIIA
                     VSDKGVIDRADTTYDEFLENADIQKQLNELWA"
     gene            3339..3860
                     /locus_tag="ACG8LA_002278"
     CDS             3339..3860
                     /locus_tag="ACG8LA_002278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HdeD family acid-resistance protein"
                     /protein_id="HFQ0204557.1"
                     /translation="MDEKRTIDWGSLILGILFVLVSLLSFQDPVGNLVAIVVVFAIFA
                     FIKGIFELFVRNRLKELTGYKGKMPLIIGIIDILVGVFFLFNIGAGVAALPFVFAVWF
                     IADSVLALFTADLARGVSEGYYWFTIIVNILGILLGIFLLFNPISSALTLSFLVGFYF
                     MLFGITHIVYAFR"
     gene            complement(4046..5776)
                     /gene="spxB"
                     /locus_tag="ACG8LA_002279"
     CDS             complement(4046..5776)
                     /gene="spxB"
                     /locus_tag="ACG8LA_002279"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047112 - pyruvate oxidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HFQ0204558.1"
                     /translation="MSKINAGIAMVKVLESWGIDHIYGIPGGSFNSIMDALYQEKTEI
                     NYIQVRHEEVGALAAAADAKLTGKVGAVFGSAGPGATHLINGLYDAQMDHVPLVAFLG
                     QVASTSMNYNSFQELNENPIFADVSVYNRTVMTPQSLPHVVDEAIKAAYEHKGVAIVT
                     IPVDLGFEEIDEQPFSTAHTHKTSVILPEEKDLLAALPYLEKAKKPVLYVGQGTRNGF
                     PQIKEFSEHFSVPVVASVLAKGIIPDDYENFLGFAGRVATKPGNEALAEADLILFVGS
                     DFPFGRAFFNPTAEFIQIDIDASKFGRRHETSLSILGDANTALQRLVELGDARPADSW
                     YLANQENKEKWVNWLKSFEDREEEPIRPEAVYKEINRIAEDDAIFVTDVGNTTIHSIR
                     LLNMNGKQKHTTSGWFATMGNGVPGGIAAQLSYPEKQVFTLSGDGGFAMVMQDIITQV
                     KYQLPIINVVFSNDSFGFIEAEQEDTEQKKFGVFLEDADFGKVGEALGANSFTVTEYS
                     QLRFAFDAAAKSDRPVVIDVKINNKRPLPVEDLHLDPRKYSEEEIQAFKEKYEVHDLP
                     VLNELYEKRL"
     gene            5941..6759
                     /locus_tag="ACG8LA_002280"
     CDS             5941..6759
                     /locus_tag="ACG8LA_002280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ZIP family metal transporter"
                     /protein_id="HFQ0204559.1"
                     /translation="MVEWLLRLEPWQQALAGTAFTYFMTALGAGLVFFFKEIKKEVLN
                     LMLGFASGVMIAASFWSLLDPAITKAEENGDIAWLVVSIGFGLGGVFLYMADKTLPHM
                     HFGPQHEAEGLPTHLKRTILLVFSITLHNIPEGLAVGVAFGAAATADNPTAAILAAVS
                     VALGIGIQNFPEGAAVSIPLRQEGLSRKKAFVYGQASGIVEPIAGVIGALLVTKVELL
                     LPYALAFAAGAMIYVVVEELIPEAQQTLSSKHHFAVFGVMSGFIIMMILDVALG"
     gene            complement(6862..7059)
                     /locus_tag="ACG8LA_002281"
     CDS             complement(6862..7059)
                     /locus_tag="ACG8LA_002281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204560.1"
                     /translation="MRQKNMFLNIFMVLLVLIAASFVISLFVSVLSGLLWFAVKVLIP
                     IALIIWLVRWIKGNTHRKNYY"
     gene            7228..7806
                     /locus_tag="ACG8LA_002282"
     CDS             7228..7806
                     /locus_tag="ACG8LA_002282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0071805 - potassium ion transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TMEM175 family protein"
                     /protein_id="HFQ0204561.1"
                     /translation="MPKNRLEAFTDAVIAIIMTILVLELHEPNGDTWEALAALGYRFF
                     IYIVSFIILAIYWNNHHHLFQVVHKINGRVLWANSFFVFALSLFPFATSWISEYINSL
                     APEMTYGFVTLTANIAYYILAKELVKANKGHEKALKAMLNNYKKSYLSIGLNVLGIVL
                     GYLVAPVAVLIANIVILAAWIIPSRTIESQYR"
     gene            7901..8038
                     /locus_tag="ACG8LA_002283"
     CDS             7901..8038
                     /locus_tag="ACG8LA_002283"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204562.1"
                     /translation="MDQKRIHVGLITSFVTMLIYLDQGHLTWTVVGVVGFLTLFTAIK
                     K"
     gene            complement(8851..9354)
                     /locus_tag="ACG8LA_002284"
     CDS             complement(8851..9354)
                     /locus_tag="ACG8LA_002284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HFQ0204563.1"
                     /translation="MRYVSKFLLGIYLFFLLWLILFKLSFNLPQFLTYSYSNVNLVPF
                     STFSFENTTVLRETTYNLIVFFPFGVLLNVNFKRLSFSKKLGIIFLVSFLAELIQFLF
                     GIGVADITDLITNTTGGLIGLWAYQLLNKHLSTNKLDRLAIILGYILFLFLIVAFLFL
                     TRTVRLQ"
     gene            9713..10738
                     /locus_tag="ACG8LA_002285"
     CDS             9713..10738
                     /locus_tag="ACG8LA_002285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HFQ0204564.1"
                     /translation="MFKTYFRFNKIQDNPFRIMNLMLLIFIVLWLGYINHDFLISSFS
                     SLGIFTFFYYQNIPMKYLLKRMFLIGCGLLVAFVLGILSTYVLWLEPFAVALVAFSSR
                     FVLRLFHISKPGGLFFAMLSAMGTSMQLPIAQLPIVSLYFFMGVVFALIAAVITKLLD
                     SRPEQTIEKATLKERFHEEPLVIIDSVFYSAALFLSVYVSHGLNLHNPYWLTLSCASI
                     LLAENLDAMKHRQVQYLIGSMGGLCVSAFLSFVPFTQLQTIFLITFLYGIAQFLVARN
                     YAVANIFLNPMALMLSTLIRGAYLISLIEYRFLGIVIGSFIGLGVAWVMTVGLQHYLT
                     VVRQKLE"
     gene            11061..11939
                     /locus_tag="ACG8LA_002286"
     CDS             11061..11939
                     /locus_tag="ACG8LA_002286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase domain-containing protein"
                     /protein_id="HFQ0204565.1"
                     /translation="MRFKDMKRGNLMKKISNEIQILAETLTLPKVVIEQMIVQAKNIL
                     DEVFEQYSHELMDPNKAKATAKKIDKVYEEEPFAALAIYLYAASQSWKKIYQPLKIPR
                     TIYLATMNAFTRFIHEHFQVTGSYRFDRGFWIWHYTSGLIFRIGELEYEMTYFPKGYT
                     DLRLEGKQCLSLHIPSDADLSQNKIRDSYESAIRFFELYFPDYHYQVMYTDTWLLSPN
                     LTKWLKKESKICLFAADYRLLSVDEQDDSGVPWIFGRVDAQIHDYPESTSLQRQAKEQ
                     LLAGEHIGSGLGILTS"
     gene            12415..12531
                     /locus_tag="ACG8LA_002287"
     CDS             12415..12531
                     /locus_tag="ACG8LA_002287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HFQ0204566.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKDVKRNSGKR"
     gene            13459..13797
                     /locus_tag="ACG8LA_002288"
     CDS             13459..13797
                     /locus_tag="ACG8LA_002288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204567.1"
                     /translation="MTQPVSSEEHDNLFRATEEFKKYQENIVPETPLASEPITDIDGN
                     QIGWYIQYEVMVVNNDSIVKNTVGLELTPIEKVSSLLTYIYTDESDETEIILTDYSKI
                     ATDKKYILWM"
     gene            13891..14121
                     /locus_tag="ACG8LA_002289"
     CDS             13891..14121
                     /locus_tag="ACG8LA_002289"
                     /inference="COORDINATES: protein motif:HMM:NF042636.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6568 family protein"
                     /protein_id="HFQ0204568.1"
                     /translation="MLVEKGKENIYYVNVAKVREDENEWKEFKSRYSINSTPTFTVYR
                     EGSIEKTVFWTKESGMSLAEVEEFLDYVSMQQ"
BASE COUNT         4553 a         2390 c         2734 g         4670 t
ORIGIN      
        1 ccactaaacg gtgttctcct gccaactcct cggtcacaag tcacaatatt caacaaacat
       61 gagaagctgt tttttgaaat tgttccttgt gactcggagc taaacggcag gctcacaacc
      121 tcttggtaaa cggtgttcaa tcagctgacc ctcggtatta gctcaaaaaa cggcaaaata
      181 tgaggaacta ttttttccgt ttttttctct aatactcagg tcaaaacgct gatttcacaa
      241 cctctgattc acggtgttcc agaagtagct tctacggaaa taagccgaaa tttcacaaaa
      301 atttgagaag caattttcgt aaattccttc ttatttcttg aagctgacca cttctgtcac
      361 aacctcttat tttgattaga acttgcgaaa ataaaccggt taaagtgtgt ctagcgcaag
      421 agatttgcta taatagacga taagggtaaa atgtaacgag aaggggttga aaaatgtgta
      481 tcaaattgta acagattctt gttgtgatct gccataccat gtattagcaa aagaaaaagt
      541 tgatttttta tcaatgaatc tccaattgaa tgatcaagag ttagtagatg acctcggaaa
      601 gacattcaat tatgaccgct acatgaatca gctgaaaaat ggtgcgatgc ctacgacatc
      661 acaaatcaat gttggccgat atttagaatt tttccgttct tatgcggaaa aacagattcc
      721 tgttttatat gtggcttttt ccagtggatt aagcggctct tacagtagtg cgcttcaagc
      781 ggttgaattg ctgaaggaag aatatgaaga ccctgagatc tatgtttttg atacaaaagc
      841 tgcaagtatt ggggaagggc ttttagtatt ggaagctgta agattgaaaa aagaaggtaa
      901 aagcatcgaa gaaaccctag agtggctgga aagtaattat ttgaaagtcc attcatgggt
      961 aacagtagac gatctgaaat atctagaacg aggcggtagg atttccaaag caagtgctac
     1021 tcttggcagt ctattgagtg taaagcctat tattacggtg gataaagaag gaaggctgac
     1081 gaatgttgac aaagttcgag gaagaaacaa gtcgatccag acaatcgtca atgagacggt
     1141 aaaaacaatc gttgcaccac ttgatcaaat cgtttatgtg gcttacgctg gggatctaga
     1201 gagcgcggag aaggcaaaac ggcttttgga agagcagata aagatgaaag atgtgaagct
     1261 ttatccctta ggaccaacga tcgccagtca cacaggctat ggctgtatcg cgattttttc
     1321 gatgggaatc agtcgataaa agcagtaact cattctgtaa aaaagcccag aaattgattg
     1381 taacaaaaac agcgactctt aaaagataga tgagcatcct atctcttaga ggtcgctgtt
     1441 tttttatttt ttaagctaaa taggccatta tgcccataac tcgttcaatt gtttttgaat
     1501 atctgcattt tccaaaaatt catcatatgt cgtatcagct cgatcgatca cacctttatc
     1561 cgaaacggca atgatgcggt ttgccaatgt ttggataaat tgatggtcat gtgacgcaaa
     1621 taagattgag ccagtaaatg ccatcaagcc gtcattcaat gctgtgattg attctaagtc
     1681 taaatggttc gttggatcat ctaatacaag tacgttagct ttcgaaagca tcatttttga
     1741 aagcatgcaa cggactttct ctccaccaga taaaacattc actggtttca atacttcttc
     1801 accagaaaac aacattcttc ctaagaagct tcttaagaag gtgttatcat cttcttcttt
     1861 acttgcatat tgacgcaacc agtctaaaat cgttagatca gtatcgaatt ctttcgttgt
     1921 atcctttggt aaataagaat tacttgttgt cacaccccaa cgtactgttc cagtatctgg
     1981 cgtaatttca cccatgataa ctttgaatag cgttgttgtt gttatatcat tttctgcgac
     2041 gaaagcgacc ttgtcttctt tgctcaaatt aaaagatata tcatctaaaa ttttctttcc
     2101 atcaatcgtt acacttacat tttctacctg caataagtcg tttccaatct cacgttcagg
     2161 tttgaatcca acgaatggat aacgtctaga agaaggttgg atatcgtcta aagtaatttt
     2221 ttcaagcatt tttttacgtg aagttgcttg ttttgatttt gatgcattcg cactaaagcg
     2281 ggcaataaat tcttggagtt ctttgatttg ttcttctttt ttggcatttg cgtttgcttg
     2341 aagtttagcc gctagttgac tagattccaa ccaaaaatca taatttccta cataaagttt
     2401 gattttacca aaatctagat ccgccatatg tgtacatact ttgttcaaaa agtgacggtc
     2461 atgggataca acgatcacag tattttcaaa attgatcaaa aattcttcca gccaattgat
     2521 cgattggata tccagaccgt ttgttggttc gtctagcaaa agaacatcag gtttaccaaa
     2581 tagtgtttgt gctaataaca cttttacctt ttgtccacca gttaattcac tcatttgctg
     2641 atggtgcaat tcttcaggga tgttcagacc ttgcagtaaa acagctgctt ctggttcagc
     2701 ttcccatcca ttaagctcag caaattctcc ttctaattca gctgctcgaa taccatcttc
     2761 gtcagtgaaa tcctctttca tgtaaatcgc atctttttct ttcagcactt catacagacg
     2821 cttgtgtccc atgatgactg tttcaagtac agtatagtct tcatagtcgt aatggttctg
     2881 tttcaatacg gccatccgtt catctggtcc catagtaacg gaacctgtgg aaggctgcag
     2941 atcccctgat aacactttaa ggaacgttga tttacctgca ccatttgcac caatcaagcc
     3001 atagcagttt ccgggggtaa atttaatatt cacatcatca aatagtttgc ggtctgaaaa
     3061 gtgcaaactc acatcattta cagtaatcaa tttttttcct cacttttatc attattagtt
     3121 ttgacaagtc ttatagaatt atatagggga aaggtaaaag attcaaggca atcgaacatt
     3181 ctttgtgttt cacgtgaaac agaatgaaaa aaataaaaat aaaagcggag cgaaaatagc
     3241 tactatagga tttattagtt tgcaacagca taatttttga cgttatttat aagagggagt
     3301 actataaaac tgtaaaagaa atgaaagaag gattgaaaat ggatgaaaaa agaaccatcg
     3361 actggggctc attgattttg ggaattttat ttgtacttgt ctcattgtta tcatttcaag
     3421 accctgtcgg aaatttagtt gcaattgtag tagtctttgc gatttttgcc tttattaaag
     3481 ggatatttga actgtttgta cggaacagat taaaagagct aacaggatat aaaggaaaga
     3541 tgcccttaat aatcgggatc atcgatattc tagttggcgt ctttttctta ttcaatattg
     3601 gtgcaggagt cgcagcattg ccttttgttt ttgcagtatg gtttattgct gattcagttt
     3661 tagcgttatt tactgctgac ttggcaagag gagtaagtga aggatattat tggtttacga
     3721 tcatcgtcaa tattttagga attttattag gaattttctt attgtttaat ccaatttctt
     3781 ctgcgttgac attaagcttt ttagttggat tctattttat gttatttggt atcacacata
     3841 tcgtctatgc atttagataa gtaaaatcaa acaaataaaa aagccggctt ccgattacag
     3901 ttttactgtt gtaattggaa gccggctttt ttatcatgga caaatatgca cgaggtgatt
     3961 tttaggtgtc gagacaaatt tatgcaaaaa tgtgagaagc tatatacaca aattttatct
     4021 taatactcga agcatagcgc agttgtcaca acctcttttc atataattca ttcaatactg
     4081 gcaaatcatg gacttcatat ttttctttga atgcttggat ttcttcttca gaatattttc
     4141 ttggatctaa atgcagatct tctactggca atgggcgctt gttattgatc ttcacatcga
     4201 ttactacagg acgatctgat tttgcagctg catcaaaggc aaatcgaagt tgcgagtatt
     4261 ctgtgactgt aaagctattt gccccgagcg cttctccaac tttaccgaaa tctgcatctt
     4321 ctaaaaatac accaaatttc ttttgttccg tatcttcttg ttctgcttcg atgaaaccaa
     4381 aagaatcatt cgaaaagaca acattaataa ttggaagctg atatttgact tgtgtaatga
     4441 tatcttgcat gaccatagca aacccgccat caccacttaa ggtaaatact tgtttttctg
     4501 ggtagcttag ttgtgcggca attcctcctg gcacaccatt acccatagtt gcgaaccatc
     4561 cagatgtcgt atgtttttgt ttaccgttca tattcaataa acgaatagaa tggatagtcg
     4621 tgttaccgac atctgtgacg aaaatcgcat cgtcttcagc aatacgattg atttctttat
     4681 agacagcctc tggacgaatc ggttcttcct ctcgatcttc aaaagatttc aaccaattta
     4741 cccatttttc tttattttct tgatttgcta ggtaccagct atcagcaggg cgagcatccc
     4801 ctaactcgac aagtctttgc aaagctgtgt ttgcatcacc gaggatcgac aaagatgttt
     4861 catggcgtcg tccaaatttt gacgcatcga tatcgatttg gataaattca gcagttggat
     4921 taaaaaatgc acgtccaaat gggaagtcgc taccgacaaa taagatcaga tcggcttctg
     4981 ccaatgcttc atttccgggt ttagtagcga cacgtccagc aaaaccaaga aagttttcat
     5041 aatcatcagg aataattcct tttgctagaa cggaagcgac aacaggaact gaaaaatgtt
     5101 ctgagaattc tttgatttgc ggaaatccgt ttcgcgttcc ttgaccaaca taaagaactg
     5161 gtttttttgc tttttcaaga taaggcaaag cagctagcaa atctttttct tctggtaata
     5221 tcacacttgt tttgtgagtg tgagcggtgg agaaaggttg ttcgtcaatt tcttcaaaac
     5281 caagatcaac agggatagtc acgatagcca cgcctttatg ctcataggcg gctttaatgg
     5341 cttcatctac tacatgcgga agactttgtg gtgtcatgac tgtacgattg tatacgctaa
     5401 catctgcgaa aataggattt tcatttagtt cctggaaaga gttatagttc atggatgtag
     5461 aagcaacttg tcctaagaac gctactagag gcacatggtc catctgtgca tcatacaaac
     5521 cattgatcaa atgtgtcgca ccaggtcctg cagagccgaa gacagcgccg actttccccg
     5581 ttaattttgc atctgcagcg gctgcgagtg cgccgacttc ttcatgacga acttgaatgt
     5641 agttgatttc ggttttttct tgatatagcg catccataat tgaattgaaa gatcctccgg
     5701 gaatgccgta aatatggtcg ataccccagc tttcaagaac ttttaccatt gcgattcctg
     5761 cattgatttt tgacatggtg tttcactcct ttagcaatga tgatacataa attttttgta
     5821 tctagagtat agaacttttt atcgaaaatc ccaactaatt cgtcttttca caaaaatgta
     5881 gtcatgtttt tgggaatatg ctagagtagt acatagatag attcaagaga ggggaatggc
     5941 atggttgaat ggctattgag acttgaacct tggcagcaag cacttgctgg gacagctttt
     6001 acttatttta tgacagctct tggtgccggg ttggtttttt tctttaaaga aatcaaaaaa
     6061 gaagtgctaa acttgatgtt aggatttgct tctggtgtca tgattgctgc aagtttttgg
     6121 tctttgttag atccggctat tacaaaagca gaagaaaatg gagatattgc ttggctagtt
     6181 gtaagtattg ggtttggttt aggcggtgtg tttttatata tggcagataa aacactgccc
     6241 catatgcatt ttggaccaca acatgaagca gaaggattgc ctacccattt aaaacggacg
     6301 atcttgcttg ttttttctat tacattgcat aacattcctg aaggtttagc cgtgggggta
     6361 gcattcggtg cagcagcaac tgcggataat ccgacagccg ctatattagc cgctgtttcg
     6421 gtggcgctag gtattggtat ccaaaacttc ccagaaggag cagctgtatc aatcccgttg
     6481 cgacaagaag gtctgagtcg taaaaaggcc tttgtttacg gacaagcttc tggaatcgtt
     6541 gaaccaattg ctggagtgat tggagcgcta ctagtaacga aagtggagct gctgcttcct
     6601 tatgcacttg cttttgccgc aggagcaatg atttatgtcg tggtggaaga attgatccct
     6661 gaagcacagc agacattgtc cagcaaacat cattttgcag tttttggcgt catgagtgga
     6721 tttatcatta tgatgatttt ggatgtggca ttaggataaa taaaaaaaat atatatgata
     6781 tatcaaatag ggccgcgaac ttatatcgcg accctatttt tttagtaagt tatatcataa
     6841 tgaagtgaat ggtatcatac attaataata gttttttcta tgtgtatttc ctttgatcca
     6901 gcgaacaagc cagatgataa gtgcgattgg gattagaact ttgaccgcaa accataaaag
     6961 cccgcttagg acactgacaa aaagactgat gacgaagcta gctgcaatta gcactaaaag
     7021 aaccatgaag atatttaaga acatattttt ttgacgcata caaaaccctc ctcttgttca
     7081 ttctttacta tagaaaaagt ataacaggga ttgtttaaaa acacctccaa ctgaagactg
     7141 atttttactt catctactta aatgatcaaa caattgcttt ttctctggtt tatcatctaa
     7201 aatagagcgg aaaaggagga gaatatcatg cctaaaaatc gtcttgaagc atttacagat
     7261 gctgtaatcg cgattatcat gactatttta gttttagaac ttcatgaacc taacggagac
     7321 acgtgggagg cgctcgctgc attaggttac cgatttttta tctatattgt cagttttatc
     7381 attttagcga tttattggaa caatcatcat catttatttc aagttgtaca taagataaat
     7441 ggacgggtct tatgggcgaa cagtttcttt gtttttgcgc tttcgctttt tccgtttgca
     7501 acttcatgga tcagtgagta catcaatagc ctggctccag aaatgactta tggttttgtt
     7561 accttgaccg ctaatattgc gtattatatc ttggcaaaag aacttgtcaa agcaaataaa
     7621 ggccacgaga aagcattgaa ggcgatgttg aataattaca agaaatcgta tctatcgatt
     7681 ggtttgaatg tgttaggaat tgtcttaggg tatttagtag cgccagtagc cgtgctgatc
     7741 gcaaacatcg tgattctagc tgcttggatc atcccaagtc gtaccatcga atcacaatat
     7801 cggtaaaatg atccgtgttt aaaatttaag agaaaaatat agaaaaaata aataaacgat
     7861 caaatatccg agtgatacta gtattcaaag agggatgcag atggatcaaa aaagaattca
     7921 tgtaggactg attactagtt ttgtcacgat gcttatttat ttggatcaag gtcatttgac
     7981 ttggacagta gttggtgtcg taggattttt gacattattc acagcaataa aaaaataaac
     8041 atctttatgt aatctgatgt tctatctatt taagaaaagc atgtttacag cagtatgatt
     8101 ctgttgtaaa cgtgttttta tttgtggaaa atttaatttt tagaaaagtg tatcgaaaaa
     8161 tagatagtta gtttttccac agtggataac ttcgtaagag ataaaaataa aaaattagtc
     8221 aaagaagggc gtatagattt cttttgatag gagatataca acagaaatga ataaatatta
     8281 acgtgttttc aaacagtata aaacggtgtg gtttttggaa taaaaaaata acatatctca
     8341 ttttacactt ttgttatttt atacttaaaa aataacgaca cagaaaatac cgtgtctcag
     8401 atttctctac tacttctaaa aactactgtt tttttccttt gaaatgcctt caaaaagtag
     8461 gatcaggcag aatatactgg cagaatcaag gagaagggag cctaaataag gagaaaaacc
     8521 atagaaaata taaagtaatt acttataaaa caagcttttt atagaaaaat aatatacctg
     8581 agtagggtat aaattaagac ggaattcctt tctagattga gatattgact aggaagaatg
     8641 ttaagatttt aagcctttaa gctaaaaaaa aacccttttt gttaaataag gggaatatag
     8701 cctgtcagtt tcaaactgca agtcgtcctg ctgcaataat atagtagatt agagatgaaa
     8761 atagattttt ttaaaccaat gactgaataa aaagaccgtc atagatacac attggaatgt
     8821 gtctattacg gtcttttttt acgaacgatt ttattgaaga cggacagttc gggtcaaaaa
     8881 taaaaaagct acgatcagaa ataagaataa aatgtatccc aaaataatgg ctagacggtc
     8941 taacttattt gtcgatagat gtttgtttag aagttgatag gcccataaac ctatcagtcc
     9001 tcctgttgta ttagttatca aatcagtgat gtccgctacg ccaataccga ataggaattg
     9061 aatcaattct gccaagaagc ttacaaggaa aataatccct aattttttag aaaaagaaag
     9121 tctcttgaaa ttgacattca aaagcacccc aaaaggaaaa aagacaatca agttataagt
     9181 ggtctcacgt aataccgtcg tattttcaaa agaaaaagta gaaaaaggga cgagattgac
     9241 attgctgtaa gaataagtga gaaattgtgg aagattaaat gatagcttga ataaaatcaa
     9301 ccataataga aagaataaat aaatccctaa taaaaatttt gatacatacc gcatagacat
     9361 ctcctccatt taaaaagtat accatcgaaa accgctgaaa aatcataaaa aagtatgaag
     9421 tttaaggacc aacgtagtta tcgtacgaaa attagaagct tttttttgtt gggaatccgg
     9481 tttctttaac aaagctaaga tagcgagttg cttggaaaag ttgctatctt ttttctgtca
     9541 aaacgactcg gaatgttcgt tttttgttct aatttctcca agttgtttac tttttgatac
     9601 taagtttatg aaaaatcaag aaatagttgt tatactaggt aatgctgaca aacgggattg
     9661 gcatttcatc ttggttcagc tttttttcca attactagga aggagggata gattgttcaa
     9721 gacttatttt cgtttcaata aaatacaaga taatcctttt cgtatcatga atctgatgct
     9781 acttatcttt attgtattat ggttaggtta cataaatcat gattttttga tttcaagttt
     9841 ttcatcatta gggatcttta cttttttcta ttatcaaaac ataccgatga aatatttgct
     9901 gaaacgtatg tttctgatcg gttgcggact gttggttgct ttcgttttgg ggatcttatc
     9961 gacttatgtt ttatggcttg aaccatttgc cgtagctttg gttgcttttt ccagcagatt
    10021 cgtgttgcga ttattccata tttctaaacc aggtggcttg ttttttgcga tgctttctgc
    10081 catgggaacg agcatgcagc tgccaatcgc tcaattaccg atcgtctcac tttatttttt
    10141 tatgggtgtc gtttttgccc tgattgcggc agtgattaca aaattactgg attcacggcc
    10201 tgagcagaca attgaaaaag caactttaaa agaaagattt cacgaagagc ctttagtgat
    10261 cattgattct gttttctaca gcgctgcctt atttctttcc gtttatgtca gtcacggctt
    10321 gaatctgcat aatccttatt ggttgacctt gtcatgtgca tcgattttgc tagcagaaaa
    10381 cttggatgcg atgaagcatc gacaagtcca atatctgatt ggatcgatgg gtgggttatg
    10441 tgtgtcggca ttcttgtcat ttgtgccgtt tacgcagttg cagaccattt ttctgatcac
    10501 ttttctatat ggaatcgcac aatttctagt tgctagaaat tatgcagttg ctaatatttt
    10561 tcttaatccg atggcgttga tgctatctac acttattcgt ggagcatact tgatttcttt
    10621 gatcgaatat cgttttttag ggatcgtcat aggaagtttc atcggtttag gtgttgcgtg
    10681 ggtaatgacg gttggtttgc aacattattt aacggttgtt cgtcaaaaat tagaatagaa
    10741 ggacaaatat atgtgccaaa agaggttatg acaagatttt tgtcacaacc tctaattcaa
    10801 ggtgttcaaa agccagattc tcagcattaa gtcaaattca cacaaaaatg tggaaaggaa
    10861 ctttcaaaaa aattttatat ttattctatc aaaaaatttt gtttatgatg gtaactgaat
    10921 aaactttcct gagatggtca atgctttcct tgaaagtctt acagatattc tttcttcata
    10981 gaaagtttaa gttttatagt tagtgtacaa taaaagtatg tttataccat atggtgtccg
    11041 gataatcagt catttaaaca atgaggttca aagatatgaa aaggggaaat ttgatgaaga
    11101 aaataagcaa tgaaatccaa attctggcag aaactttaac tcttcccaaa gtcgttatag
    11161 agcaaatgat tgtacaagca aaaaacatcc ttgatgaggt gtttgagcaa tatagtcatg
    11221 aactaatgga tcctaataaa gcaaaggcga ctgcaaagaa aatagacaaa gtctatgaag
    11281 aggaaccttt tgcagcatta gctatttatc tatatgcagc ttctcaaagt tggaaaaaaa
    11341 tttatcaacc attgaagatt ccaagaacta tctatttggc aacaatgaat gcttttacta
    11401 gatttattca tgaacatttc caagtaacag gaagctatcg ctttgaccgt ggtttttgga
    11461 tttggcatta cactagtggc ttgatctttc ggattggtga attggagtac gaaatgacat
    11521 attttccgaa agggtacacg gatctaagat tagaaggaaa gcagtgcctt tctcttcata
    11581 ttccttccga tgcagattta tctcagaata agataagaga tagttacgaa agtgccattc
    11641 gtttttttga actttatttt cctgattacc attaccaagt gatgtacaca gatacttggt
    11701 tactatcacc caatcttact aaatggttga aaaaagagtc aaaaatctgt ctttttgcag
    11761 ccgattatcg attattatca gttgatgaac aggacgatag tggagtccct tggatctttg
    11821 gacgagtaga tgcccaaata catgattatc cagaaagtac gagtttacag cgacaagcaa
    11881 aagagcaatt gcttgcaggc gagcacattg gctctggctt aggtattctt acttcataag
    11941 tttagtactt cgaaatagtt taaaagagcg tgagacaaaa gtaaagaaca cttttgtctc
    12001 acgctctaaa cacgtataaa cggcggaagc agaagcaact ccttcggaaa taagctgaaa
    12061 ttcacaaaaa tttgaaaagc aattttcgtg aatttcttct tatttcttgg agttaaacgc
    12121 ttctgtccca gcctcttttt tagtgttcta tcgaacacac agtacgttca ataggtaaac
    12181 tagctataac aatagatatt aaagttaacg gacaagaggg ccttttttag gtagctaaaa
    12241 cgtaataatg aaaatttatt tccagagata ggagtcaatc agctagtctg atcgactgtt
    12301 ttaacaagtt gactttcatt ttaacttttg ataccattta aaacacaaat cgtaattgtt
    12361 tcgatttgtg ttttttagca tgactacaat caaagaagaa agtgggtcgt ccatatggaa
    12421 aaaacagata tctcaagtgc ataccgccgc ttgaaaagcc caaatatcaa aacacgaaaa
    12481 cgtgcgctga agatcatcaa agatgtgaaa cggaatagtg ggaaaaggta agaagaagga
    12541 aacttaatta aaaaaatagc cgaaaaacgt ttttcggcta ttttcaataa tcggtttttg
    12601 tgtaaggttt ccgaaagaac tgctgttgat tttccatttt taacatatga taaattggta
    12661 gaatctttct tttcaaattg ataccattcc ctaattccag ttatatagtt aactacagaa
    12721 ccacaaagca cgtacgttta taaaagtatt atctgtagtt atttttcaat tccctttcaa
    12781 cctcttattt tgaccagtag tattgatcac tttacctttt aacacctttg ttcgtttttg
    12841 aaacattttt agtcaagaat ggaaacgtaa ctacataatc aaaggttttg cgaaatattt
    12901 catgaaatat ttcatgtaga agcgagcaat acggttgcaa ataaccatta tcgtttaata
    12961 agcagttacg aaagctccca atatctctaa cgttcagctc actccatttc ttttcttcaa
    13021 aaaaatcagt gattcgtatc tctttctatt tgtcgaaaaa gttaacttta aaaagtaacg
    13081 ccgaaaaaat atgcaaaaaa ataaaaaagc agttactatt gctagaataa catcaaggaa
    13141 taataagttt tggttttcag ataatagtcg ataagttgtg tattggaatt ttagatacag
    13201 taataaagta tttttcatga aattttgtga gaatcactat tacaagtatc tttaataaaa
    13261 ttaatggtta aggaggaact taaagtagaa tgtaaatgaa tagttgtagt cagtcgattg
    13321 tgatactaga ctcaaagttg caggaataag tttttcaatt tgtgattgga agataaaaaa
    13381 tgaaaaagaa gggctttttt ttatactttg ttgattgtag tgtttatttt ccctctgttt
    13441 agccaagtaa cattttctat gactcaacca gtttcaagtg aggaacatga taaccttttt
    13501 cgtgctacag aagagtttaa gaaatatcag gaaaatattg ttccggagac tccattagct
    13561 agtgagccaa ttactgatat tgatggaaac caaataggat ggtatataca gtacgaagtt
    13621 atggtggtaa ataatgactc aatagtaaaa aatacagtag gcttagagct aacaccgatt
    13681 gaaaaggtga gttcattgtt aacgtatatt tatactgatg aaagtgacga gactgagatc
    13741 attttaacgg attactcaaa aattgctact gataaaaagt atatattgtg gatgtagaca
    13801 ctagtgaaat actttatgat atagaaattg atgaaaattt actagatgta gcacaagaaa
    13861 tcgatcatca aaagcaggaa gctattcgat atgctggtag aaaagggaaa agaaaatatt
    13921 tattacgtga atgtagcaaa agttagagaa gatgaaaatg agtggaaaga attcaagagt
    13981 cgctactcaa ttaactcgac tccgacattt acagtttaca gagaaggatc gatagaaaaa
    14041 actgtttttt ggactaaaga aagtggaatg tctttagctg aagtagaaga gtttttggat
    14101 tatgttagta tgcaacagta agggagttct tattatgaaa aattttgaca catattatgt
    14161 tattgttttt tcgatatctt tgctgttaat attactaact ttaatgcagt ataaagagta
    14221 tccagagtat tttattttaa cttttgtata tttagtaagt agctacacac ttctatataa
    14281 attcagaagt tcttctagag tttctaaagt ttgtttctta attagcttat tgattctata
    14341 atatttt
//
LOCUS       DAZKKZ010000066        14197 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.068, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000066 DAZKKZ010000000
VERSION     DAZKKZ010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14197)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14197)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14197
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.068"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(12..482)
                     /locus_tag="ACG8LA_002290"
     CDS             complement(12..482)
                     /locus_tag="ACG8LA_002290"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004602 - glutathione peroxidase activity
                     [Evidence IEA];
                     GO_function: GO:0043295 - glutathione binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HFQ0204569.1"
                     /translation="MSIYNFETTLEDGTVYSLKKYAGKPIIIVNTATKCGLAPQFKQL
                     EELYQAYQTQGLVILGFPSNQFKQELDSATEAAEACKTTYGVTFPMHQLIDVNGENTD
                     PLFTYLKNEAPGTVTKAIKWNFTKFLIDRNGKVIERFAPQTSPLKMTAAIESVL"
     gene            complement(641..1099)
                     /locus_tag="ACG8LA_002291"
     CDS             complement(641..1099)
                     /locus_tag="ACG8LA_002291"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0043768 - S-ribosylhomocysteine lyase
                     activity [Evidence IEA];
                     GO_process: GO:0009372 - quorum sensing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HFQ0204570.1"
                     /translation="MRMNVESFNLDHTKVKAPYVRVADRKTGAHGDVIIKYDVRFKQP
                     NKEHMDMPSLHSLEHLTAELIRNHADYIVDWSPMGCQTGFYLTVLNHESYEDILDVLE
                     ATMKDVLEATEVPASNETQCGWAASHTLEGAQALAREFLAKRDEWSEVEA"
     gene            complement(1270..2415)
                     /locus_tag="ACG8LA_002292"
     CDS             complement(1270..2415)
                     /locus_tag="ACG8LA_002292"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0019346 - transsulfuration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HFQ0204571.1"
                     /translation="MHIQTKLIHGGISEDPTTGAVSVPIYQTSTYRQDGVGQPKQYEY
                     SRSGNPTRFALEELIADLEGGVRGFAFSSGLSGIHAVFSLFQAGDHILLGDDVYGGTF
                     RLFDKVLTKNGLEYTIIDTSNLDKIEQSIKPNTKALYLETPSNPLLKITDLEKSATLA
                     HQHGLIVIADNTFATPYFQRPLDLGSDIVVHSGTKYLGGHSDVVAGLVTSNHKDLADQ
                     IGFYQNAIGAVLGPQDSWLLQRGIKTLSVRMEEHQKNAFVVADFLFSHPAVEKVYYPG
                     LPDHELHGVAKQQMSGFSGMISFTLKNEESAIPFVESLQLFTLAESLGGVESLVEIPS
                     VMTHASIPKEKREEAGIKDGLIRLSVGIEYGQDLINDLAQAFDRIKN"
     gene            complement(2428..3345)
                     /locus_tag="ACG8LA_002293"
     CDS             complement(2428..3345)
                     /locus_tag="ACG8LA_002293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent cysteine synthase family protein"
                     /protein_id="HFQ0204572.1"
                     /translation="MIISTITEAIGSTPLYRFDNQHYSMPKGSAIYAKLEYLNPGGSI
                     KDRLGSYLIKEGFAQGKINEKTTIIEPTAGNTGIGIALAALTYKLRTVFVVPEKFSLE
                     KQQLMKALGAKIIHSPSEQGIIGAISKSKKLAEEISNSYLPLQFENKDNPAAYYHTLG
                     PEIFHEIKENIHSFVAGIGSGGTFAGTSTFLKEKYPDIRIIGVEPEGSVLNGGDPAPH
                     EIEGIGVEFIPPFLSPLSINQIETISDVEGFNYTRQLAREQGLLVGSSSGAAFAAALR
                     EIRRLPPGHRVVTIFPDAADRYLSKNIYL"
     gene            3773..4336
                     /gene="efp"
                     /locus_tag="ACG8LA_002294"
     CDS             3773..4336
                     /gene="efp"
                     /locus_tag="ACG8LA_002294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HFQ0204573.1"
                     /translation="MISASDLRAGMTFVQDGKLIKVLDASHHKPGKGNTVMRMKLKDV
                     RSGATYDTTFRPEEKFEKAHIDTKPVQYLYTMDDTAFFMDLETYEQYEIPVETVEEEM
                     KYILENMEVKIQFFGSEVIGVQLPTTVVLRVVETQPSIKGATVTGSGKPATMETGLVV
                     NVPDFIETDELLEINTAEGSYVKRASK"
     gene            4437..4607
                     /locus_tag="ACG8LA_002295"
     CDS             4437..4607
                     /locus_tag="ACG8LA_002295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204574.1"
                     /translation="MKNKKVFDFIYILKDEWQKLEKEKTALIYEEIEMIHKIENIRTI
                     PNYIEAKIFFHH"
     gene            4822..6081
                     /gene="lysA"
                     /locus_tag="ACG8LA_002296"
     CDS             4822..6081
                     /gene="lysA"
                     /locus_tag="ACG8LA_002296"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008836 - diaminopimelate decarboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HFQ0204575.1"
                     /translation="MTELIIGGVTASTLAEKYKTPLYVYDEEKMRQTMLSFKRGFVSK
                     RFDTKVLYASKAFQTIEMLHLVREYGFGLDVVSGGEIYTALQADFPRDTIYFHGNNKT
                     PEELIYALENDLLHIVADNLMEVELLAELSQRYLKKICIMLRLNVGVEAHTHEYIVTA
                     HIDSKFGMSYESKECQQALQLIKESSYLELEGFHAHIGSQIFDVTAWLAEIDKLTNYL
                     TDFDQPLSLNLGGGFGIRYTQNDQPIPVEEALKKLIEYTEEALEKRKLTIRQLLIEPG
                     RSIVGEAGTTLYTIGFIKKTPHKKYYFVDGGMTDNIRPALYQAEYDCDLAAKLSEEKT
                     EKVTIAGKMCESGDVVIKEAYLPKAESGDLLAVYSTGAYGYSMSSNYNRATRPAVVFV
                     NNGQSRLIVRRQAFSDLLRGEVSYDPS"
     gene            6068..6868
                     /gene="dapF"
                     /locus_tag="ACG8LA_002297"
     CDS             6068..6868
                     /gene="dapF"
                     /locus_tag="ACG8LA_002297"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008837 - diaminopimelate epimerase
                     activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HFQ0204576.1"
                     /translation="MILHKYNGCGNDFILLDYAEDTDYSQLAASLCTKEKYDIDGLIA
                     VKIDPLEMIYYNKDGSRAPMCGNGIRCFARYVNDQNMMNEQEFNVETLAGTRKITVLD
                     PSPFYCSVDMGVPDDSPEKIKANQTYPIKNQEIEINGEKVTITSLFLGTIHTVVFVEN
                     AREEVWRKRGELICHHPLFKEKTNVNFVEVVNEQELIVRTYERGVGWTLACGTGCCAS
                     YVVAKETGKISADQVVVHLEQGDLMTSGEDAIQMAGPAVHEWTRILEE"
     gene            6871..7752
                     /gene="dapA"
                     /locus_tag="ACG8LA_002298"
     CDS             6871..7752
                     /gene="dapA"
                     /locus_tag="ACG8LA_002298"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008840 - 4-hydroxy-tetrahydrodipicolinate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HFQ0204577.1"
                     /translation="MIKGSIVALITPMNEEGSVDYAGLEKLIQFHLDEQTDGLLVLGT
                     TGESSTLTQSEEEQILQLTVKKVAGRVPVIAGAGTNNTKETIEKAKHFASLGADALLV
                     ITPYYNKTSDAGLAAHFTAIAEASPIPLILYNVPSRTGMSIPIHVLVNLAEHPNIIGL
                     KEASGDMAYVMDAARLIGEEFFLYSGNDDLILPVMSVGGSGVISVWANIQPKIVHELV
                     KDTQDGRWQQAKEKQLNALELIHALFSETNPIPVKAAMSLLDLPSGPLRLPLVSLSKE
                     KKKQLAQLLLKERTVEK"
     gene            7749..8465
                     /gene="dapB"
                     /locus_tag="ACG8LA_002299"
     CDS             7749..8465
                     /gene="dapB"
                     /locus_tag="ACG8LA_002299"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008839 - 4-hydroxy-tetrahydrodipicolinate
                     reductase [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HFQ0204578.1"
                     /translation="MKIGLIGSGQMGNRVEEVAQERGDTVLLLRTAPKEATTLAFTEL
                     PELLIDFSHPDNLEKILSYSLSYQLPLVIGTTGYTQSQFQEIKEHAKHVPVMYSANFS
                     FGIMVMNQLIKQAAAMLQGWQIELIEKHHSRKKDAPSGTANMLLQTIQEVQKLQPVYN
                     WQGKKREENQIGVHSIRAGSLPGEHDVLFAATDEIFTIKHESFSNRIFAAGAVEAADW
                     LKDQSPGYYKLEDLLMDKGV"
     gene            8471..9166
                     /gene="dapD"
                     /locus_tag="ACG8LA_002300"
     CDS             8471..9166
                     /gene="dapD"
                     /locus_tag="ACG8LA_002300"
                     /EC_number="2.3.1.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047200 - tetrahydrodipicolinate
                     N-acetyltransferase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HFQ0204579.1"
                     /translation="MEAQEIIRYIQTASKKTPVKVYLNVTEPIEFKESKVFGEGSSFV
                     VFGDYETIAPVLEAESEKIIEIEIETAARYSAVPLLDIKKINARIEPGAIIRDQVSIG
                     NNAVIMMGAIINIGAVIGENTMIDMGAVLGGRATVGKNCHIGAGAVLAGVIEPASAKP
                     VIVEDGVLVGANAVIVEGVHIGKDAVVAAGAVVLEDVAAETVVGGIPARVLKISDDQT
                     KENTALIAALREL"
     gene            9182..10183
                     /locus_tag="ACG8LA_002301"
     CDS             9182..10183
                     /locus_tag="ACG8LA_002301"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004073 - aspartate-semialdehyde
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HFQ0204580.1"
                     /translation="MREIDTCIVGATGLVGQTMLKVLEEYDFPVGRLKLLASKRSAGK
                     VCVFKKKKHTVQELTETSFEGYDLALFSAGASVSKEFAPIARSQGLFVIDNSSAWRED
                     SDIPLIVPEVNLEDYTLNRLIANPNCSTIQAVLPLKALQEAFGIQRVNYSTYQAVSGS
                     GQKGIEDLHRTQNDEEPVLYPYNISQTVIPEIDQPLENGYTKEEQKMINETRKILHQP
                     ALPVSATCVRVPIENGHGVSVAVQLQKEFTTEEIRECLSQFPGIQLEDDLAAHKYPTS
                     ILARGTDMVYVGRIRKDTSLENGLLFYTTADNIRKGAAANAVQIAAALMQKIAEVAR"
     gene            10180..11541
                     /locus_tag="ACG8LA_002302"
     CDS             10180..11541
                     /locus_tag="ACG8LA_002302"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004072 - aspartate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HFQ0204581.1"
                     /translation="MSNTLKVAKFGGTSMSHEEQFKKVRTIVLSDPNRQVIVVSALGK
                     RTSDDDKVTDLLYLIYAYLQHHVDWTPLWKRICDRFIQVRDVLALQLPIEDELARIQK
                     QLEDEKITEDYLVSRGEYLTAQLMAEYLGYQFIDAKDLIFFDYDGKIDQEKTAQEITK
                     AFKRYPKMVVPGFYGANPAGKEKLLGRGGSDITGAILAKMLQAESYENWTDVSGIMMA
                     DPRIIDHPKIIEEISFRELREMAYMGANVLHEAAVFPVQEADIPIQIKNTNDPFAQGT
                     KISNHEIEKENGLTGIAGRKDFLSITLFKRHMSDEIGFIWKAMSIFAKHEISIEHIPS
                     GIDNIGVIVSAEAIADKLFLITKELKETLGVEEIVVIEDLALISVVGGPHKELIGLSG
                     KVLSILNKLEIRTSILSQGAQELNLIIGVPNNQYETVVKGIYEGMVNTDAERISNGTP
                     SNS"
     gene            11501..12652
                     /locus_tag="ACG8LA_002303"
     CDS             11501..12652
                     /locus_tag="ACG8LA_002303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HFQ0204582.1"
                     /translation="MLKEYRMALHQIPEIGFHEFKTKKYLYEQVKNSEAVIHEIGETG
                     LLLYFDNQQEETIAFRTDIDALPVKEETNLSFASKHEGYMHACGHDGHMAMLLGLTDF
                     ITKHIEDLIYNVVLIYQPSEEISGGAQSVIQSGLLDKYEVQAIFGFHLWPGLAKGEVF
                     SRPGPLMAQSSETDIIIKGQSAHIASSEKGIDSLEAAVRFLKNVYDFDRQLPAEWNHL
                     MKFGQIQGGTIRNVLAGEVIVSGSIRSYSSDMQNYLKRGLDHLAEQFHSTATISFRYN
                     DGYPAVINHRGLYAALLDSNKLHELDAPVLQAEDFGIYTQQYPCVFFFLGVGDTPALH
                     DPTFDFDMDVLENGVEWYKTILFTENLLVKIDSSSKEERVNNDEFIQSI"
     gene            12627..13796
                     /locus_tag="ACG8LA_002304"
     CDS             12627..13796
                     /locus_tag="ACG8LA_002304"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HFQ0204583.1"
                     /translation="MMNLSNRFSPRLSRIEVSKIRQFDQQISSIPDVIKLTLGEPDFP
                     TPEHVKQAGIAAIEEDFSHYTGMRGLEELREAACIFQQQRYGLTYDPQTEVLTTVGAT
                     EAIASALLSVLEEGDKVLIPAPAYSGYQPLVELAGAELIPIDTSDTGFVCQPEQFERA
                     FEQYGSAVKAVILNYPNNPTGTTLSAKQLKAIAEVLKKYPVFVISDEVYAELTYSGTH
                     MSIATYLPEQTIVISGLSKSHAMTGWRVGFIFAQKALIDELIKVHQYLVTAATTMSQK
                     AAAEALINGVKDSENMKEQYQTRRDYLVQQLAPLGFEVTQPNGAFYLFCKLPAAIQTD
                     SWQFCVELAEQAKVACIPGIAFGPEGEGYIRISYASSMEKLHEACKRIKDFLTEQ"
     gene            13971..>14197
                     /locus_tag="ACG8LA_002305"
     CDS             13971..>14197
                     /locus_tag="ACG8LA_002305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HFQ0204584.1"
                     /translation="MEKIKVVIVGASHGGHQSILELLTRYGENVDITLFEAGDYISFM
                     SCGMELYLEDKVTDVNDVRNFRPENFPQSNV"
BASE COUNT         4590 a         2507 c         3022 g         4078 t
ORIGIN      
        1 tttttattaa gttaaagaac ggattcaatt gcagcggtca ttttcaatgg agaagtttgt
       61 ggtgcaaatc gttcgattac tttgccattt ctatcaatca aaaatttagt aaaattccat
      121 tttattgctt tagtgacagt accaggagct tcatttttaa gataagtaaa aagaggatct
      181 gtattttctc catttacgtc aatcaattga tgcataggga aggtaacgcc ataagtggtt
      241 ttacaagctt ctgctgcttc agtcgctgaa tctagctctt gtttaaattg attggaagga
      301 aagcctaaga taaccagacc ttgtgtctga taagcttggt aaagttcttc taattgttta
      361 aattgaggtg ctagaccgca ttttgttgca gtgttaacaa tgattatcgg tttgcctgca
      421 tattttttca atgaatagac agtgccgtct tctaaagtag tttcaaaatt ataaatagac
      481 ataaagtttt ctcctttcta ttttatataa taaaaagagc gctaaactga aaactagcta
      541 tttgttttcc cgtttagaac tcttttcaga caataaatat ttaataaaat acgaagataa
      601 gatagctata ttgcttctca tctttacgtt cttttagaaa ctatgcttct acttcagacc
      661 attcatcgcg ttttgctaaa aattcacgag ccaaagcttg tgcaccttct agtgtatggc
      721 tggcagccca gccacattgt gtttcattgc ttgcaggtac ttcagtagct tcaagaacat
      781 ctttcattgt tgcttcaaga acatctaaaa tgtcttcgta gctttcatga ttcaatacag
      841 tcaagtaaaa gcctgtttgg catcccattg gagaccagtc tacgatgtaa tctgcgtgat
      901 tgcggattag ttcggcagtc aagtgctcaa gtgaatgtag acttggcatg tccatgtgtt
      961 ctttatttgg ttgtttaaag cggacgtcgt atttaatgat gacatcgcca tgcgcacccg
     1021 tttttcgatc agctacacgt acataaggtg ctttgacttt tgtatggtca agattaaaac
     1081 tttcgacatt cattctcatt tgtaagactc ctatctgttt gttcattcgt tttgatgctt
     1141 ttcactaaag aattatttag tgaaatttac aaaaacgtct ttctacttga ttctaacact
     1201 tatcgtttcc aaggtgtagc aatctgaaat attttttaga tttttctgct aagtcgttta
     1261 ttgggacttc tagttcttga ttctgtcaaa tgcctgagct aaatcgttta tgagatcctg
     1321 accatactca attcctacag aaagacggat caagccgtcc tttatgccag cctcttctcg
     1381 tttttctttt ggaatagacg catgagtcat gacagaagga atttccacta aactttctac
     1441 gccacctaaa ctttctgcta aagtaaatag ttggagtgat tcaacaaatg gaatagcaga
     1501 ttcttcattt tttaaagtaa aagaaatcat tccgctaaag ccgctcatct gctgcttagc
     1561 aactccatgg agttcatgat cgggtaatcc tggatagtag accttttcta ctgctggatg
     1621 agaaaataga aaatcagcta ccacaaaagc atttttttga tgttcctcca tacgaacact
     1681 tagtgtcttg attccgcgct gaagtaacca gctatcttgg ggaccaagta cggctccgat
     1741 agcattttgg taaaatccga tctgatcggc tagatcttta tggttagaag tcactaaacc
     1801 agctactaca tcgctgtgtc cgcctagata tttggtaccg ctatggacaa cgatatcaga
     1861 accgagatct aaaggtcttt gaaaataagg agtagcaaat gtattgtcag caataactat
     1921 caatccatgt tgatgagcca gagtggcact tttttctaaa tcagtaatct ttagaagcgg
     1981 attgctaggt gtttcaagat aaagtgcttt tgtattgggt ttgatggatt gttctatttt
     2041 atcaagatta ctcgtatcta tgatcgtgta ctcgagacca tttttagtaa gaactttgtc
     2101 aaatagacgg aatgttcctc catagacatc atctcctaat aagatatgat cgccagcttg
     2161 aaaaagagaa aaaacggcat gaatcccaga aagaccagaa gaaaaagcga atcctcgaac
     2221 accgccttcc aaatcagcaa tcagttcttc caatgcaaaa cgagtaggat taccagatct
     2281 tgaatattca tattgtttag gctggccgac gccatcttgc cgataagtgg atgtttgata
     2341 aataggtaca ctgacagctc ctgttgtggg atcttcactg atgcctccgt ggatcaattt
     2401 tgtttgaatg tgcatgtttc tttcctccta taagtaaatg ttttttgata aatagcggtc
     2461 tgctgcgtct ggaaaaatcg taacgacacg atgaccaggt ggtaaacgac gaatttctct
     2521 taatgctgct gcaaaagccg caccactcga acttccaact aatagtcctt gttctcgtgc
     2581 taactgccta gtatagttaa acccttctac atcagagatt gtctcgatct gattgattga
     2641 aaggggagaa agaaacggcg gaatgaattc tacaccgata ccctcaattt cgtgaggggc
     2701 tggatcacca ccatttaaca cagagccctc tggttctaca ccgattattc gaatgtcggg
     2761 atatttttct ttcaaaaagg tagaagttcc agcaaaggtt ccaccactcc caattcctgc
     2821 tacaaaacta tggatatttt ctttgatttc atgaaagatt tctggcccta acgtatgata
     2881 gtaagcagca ggattatctt tattttcaaa ttgaagaggc agatagctgt ttgatatctc
     2941 ctctgcaagt tttttacttt tgctgatggc accgatgatt ccttgctcac taggagaatg
     3001 gatgatcttt gctcccaatg ctttcatcaa ttgttgtttt tctaagctaa acttctctgg
     3061 aacaacaaaa accgttctta atttgtatgt gagtgcggcc agagcgatcc caattcctgt
     3121 atttccggca gttggttcga tgatcgtcgt tttttcattg atttttcctt gggcaaatcc
     3181 ttctttgatc aaataactgc ccaatctatc tttgatactt cctccaggat ttaaatattc
     3241 tagttttgca taaatagcag aacctttagg catagaatag tgctgattgt caaagcgata
     3301 aagcggtgtg gaaccaatag cttctgtaat tgtcgagata atcatgtggg cctcctaaaa
     3361 aaagataata aaaaaaggag ctgactatta aatcagctcc ttgaaagaca tagagaaaaa
     3421 ttgagtagat aaaaagataa gttacctggt actcattcta tgaagggcaa ttaatagaca
     3481 tgacaaatag tatgctgctt ttatgcacca tacaacagca acgattcaat tgtttttggt
     3541 tgctgactgt catgtgtatc cctccaagta aaatttttat taacgatagc atgaaaaaaa
     3601 ataaaagtca aaggcttgaa agaaaaaaat atttcgatag catcgtttac ccgtgtttat
     3661 ttttctgaca aataggcatg agaccttaaa agatagagaa tactctagtt ttctggccgg
     3721 ttgtctgata caataaagtt gattatgata aagaaaagaa ggagcaaaaa taatgatctc
     3781 agcaagtgat ttaagagccg gtatgacttt cgtacaagac ggcaaactga ttaaagttct
     3841 ggatgcaagc caccataaac ctggtaaagg aaatacagtt atgcgtatga aactgaaaga
     3901 tgtccgttca ggtgcaacat acgacacaac gttcagacca gaagaaaaat ttgaaaaagc
     3961 acatatcgac acaaaacctg tacaatattt gtacacgatg gatgatacag ctttcttcat
     4021 ggatttggaa acatatgagc aatatgaaat tcctgtagaa acagtagaag aagaaatgaa
     4081 atatatccta gaaaacatgg aagtaaaaat ccaatttttc ggtagcgaag tcatcggcgt
     4141 tcaattacca acaactgtcg tattacgtgt tgtggaaaca caaccttcca tcaaaggtgc
     4201 aacagtcact ggttcaggta agccagcgac aatggaaact ggcttagtag tcaatgttcc
     4261 tgacttcatc gaaacagatg aattgttgga aatcaataca gcagaaggtt cttatgtaaa
     4321 acgtgcgtca aaataattcg ctaacggatt gataagaatt tgaaaacaga gcttgacctc
     4381 ttgaaaggca gatcatcgga tctgcctttc aagaggtttt ttgtggaatc agcaaattga
     4441 aaaataaaaa agtatttgat tttatttata ttttgaaaga tgaatggcaa aagctagaga
     4501 aagaaaaaac tgcacttatt tatgaagaaa ttgaaatgat tcataaaatt gaaaatatcc
     4561 gaactattcc gaactatatt gaagcgaaaa tattttttca tcactaaata gtgttgaatt
     4621 tatgttttta tgtataaata gcttctaata gttcgggtat tttgttttta taaccatttt
     4681 tattcttatt tttaaaaaaa tatttcgaaa tatactagac aattcagaaa attttgttta
     4741 atattattcc aataaaattc aaatctttat caaatgaaat tccaataaaa acggaaaaaa
     4801 agtgaaaaga ggaatgaaaa aatgacagaa ttgataattg gcggagtcac agcaagcaca
     4861 ttggcagaaa agtataagac acctctgtat gtgtatgatg aagaaaagat gagacaaacg
     4921 atgctgtcat tcaagcgagg ctttgtatcg aaacgttttg atacaaaagt gctttacgcc
     4981 tctaaagcat tccaaacgat tgagatgctg catttagttc gtgaatatgg attcgggcta
     5041 gatgttgtca gtggtgggga aatctatacc gctttgcaag ctgattttcc tagagatact
     5101 atctacttcc atggtaacaa caagacgcca gaggaactga tctatgcact tgaaaatgat
     5161 ttgttgcata ttgttgccga taatttgatg gaagttgaat tattagcaga attaagccaa
     5221 cgctatttaa aaaaaatctg tatcatgctt cggttgaatg tcggagtaga agcacatact
     5281 catgaatata tcgtcactgc gcatattgat tcaaaattcg gcatgagcta tgaaagtaaa
     5341 gagtgccaac aagcccttca gttgataaaa gaaagcagct atctagagtt agaaggattt
     5401 catgctcata tcgggtcaca aatttttgat gttactgctt ggttagctga aatcgacaaa
     5461 ttgacgaatt acttaaccga ttttgaccaa cctctttcct tgaatcttgg cggagggttt
     5521 gggattcgtt atacacaaaa tgatcagccg atcccagtcg aagaggcact aaaaaaactg
     5581 attgaatata cggaagaagc tttggaaaaa cgaaaactga ccattcgtca attactgatc
     5641 gaaccgggta gaagtattgt tggagaagct ggtacaacac tatacacgat tggtttcatc
     5701 aaaaagacac cacataaaaa atattacttt gtagatggcg ggatgacaga taatatccgt
     5761 ccagctctgt atcaggcaga atacgattgt gatttagcag caaaactgtc ggaagaaaaa
     5821 acagagaaag tgacgattgc aggaaaaatg tgtgaatcag gcgatgtggt aattaaagaa
     5881 gcttatttgc cgaaagcaga atcgggtgat cttttagctg tttattccac gggagcttat
     5941 ggatactcga tgagcagcaa ctacaatcga gcgacacgac cagcagttgt ttttgtcaat
     6001 aatggccaat caagactgat tgttcgcaga caagcatttt ctgatctact aaggggggaa
     6061 gtttcctatg atccttcata aatataatgg ctgcggaaat gattttatct tattagatta
     6121 cgcagaagac acagattata gtcaattagc cgcttcttta tgcacaaaag aaaaatatga
     6181 tatagacgga ttgatcgccg taaaaatcga tccgttggaa atgatctatt acaacaaaga
     6241 tggcagccgc gcgccgatgt gcggaaatgg cattcgctgt tttgctcgat acgtaaatga
     6301 tcagaacatg atgaatgaac aggaattcaa cgtagagaca ttagcaggca caagaaaaat
     6361 tacggtgttg gatccctcac ctttttattg cagcgtagat atgggagtgc cagatgattc
     6421 tccggaaaaa atcaaagcta atcaaactta tccaataaaa aaccaggaaa tagagatcaa
     6481 tggtgaaaaa gtaacgatca ctagtttatt tttaggaacg attcataccg ttgtttttgt
     6541 tgaaaatgcg cgtgaggaag tctggagaaa aagaggtgaa ctgatctgtc atcatccttt
     6601 gttcaaagaa aaaaccaatg tcaactttgt agaagtagtc aatgaacaag aattgatcgt
     6661 ccgtacctat gaaagaggag taggttggac acttgcttgc ggtacaggtt gctgtgcctc
     6721 ttatgtggtt gctaaggaaa ctgggaaaat ttcagcagat caggtagttg ttcacttgga
     6781 acaaggagac ttgatgacct ctggtgagga tgcgatacaa atggctggcc cagcagttca
     6841 tgaatggaca agaatattgg aggaatgaag atgataaaag gttcgatcgt ggcgctgatc
     6901 acgccgatga atgaagaggg atcagtagat tatgctggtt tggaaaaatt gatccaattc
     6961 catttagatg aacaaacaga tggattatta gttttaggta caacaggaga atcttctacg
     7021 ctcacacaat ctgaggagga gcagatcctt caactgacag taaagaaagt ggctggccgt
     7081 gtgccggtga ttgcaggagc tggaacgaat aatacgaaag aaacgattga aaaagcgaag
     7141 cattttgctt ctttgggggc agacgcactt ttggtcatca ccccttacta caacaaaaca
     7201 agtgatgcag gactagctgc tcattttaca gcaattgcag aagcctcacc gattccgctt
     7261 attttgtata atgttccttc tagaacaggc atgtcgattc caatccatgt attagtaaat
     7321 ttagcagaac atcctaatat cattggtttg aaagaagcct caggagatat ggcttatgtg
     7381 atggatgccg ctcggttgat tggagaagaa ttcttccttt acagtggaaa tgatgatttg
     7441 atcctaccag taatgagtgt aggaggaagc ggtgtaataa gtgtatgggc gaatatccaa
     7501 cctaaaatag tccatgaatt agtaaaagat acgcaggacg gaagatggca gcaagcaaaa
     7561 gaaaagcaat taaatgcact tgaactgatc catgccttgt tcagtgagac caatcctatt
     7621 cctgtcaaag cagccatgtc attattagac ttaccttccg gacctctacg cctgccttta
     7681 gtttctcttt caaaagagaa aaagaaacaa ttagctcagc ttttgttaaa agaaaggacg
     7741 gttgaaaaat gaaaatcgga ctgattggca gtggacagat gggaaataga gtcgaagaag
     7801 ttgcacaaga aagaggagat acggtccttc ttttacggac ggcacctaaa gaagcaacta
     7861 cgcttgcttt tacggaactg ccagaactgc ttattgattt ttctcatcca gataatttag
     7921 agaaaatcct ttcgtatagc ttatcatatc aacttccgtt agtcattggc acgacaggtt
     7981 atacacaatc acagttccaa gaaataaaag aacatgccaa acatgtacct gtgatgtata
     8041 gtgctaattt ttcgttcggc atcatggtga tgaatcaact aatcaagcaa gcagctgcaa
     8101 tgttgcaagg ctggcagatc gaactgattg aaaaacatca tagtcgtaaa aaagatgcac
     8161 catctggtac tgcaaatatg ctgcttcaaa caatccaaga agtgcaaaag ctgcagcccg
     8221 tatacaactg gcaagggaaa aaaagagaag aaaaccaaat tggtgtacac agtattcgtg
     8281 caggttcttt acctggtgaa catgatgtat tgtttgctgc tactgatgaa atatttacga
     8341 tcaaacatga atctttttct aatcgaatct ttgctgcagg cgcagtagaa gcagcggact
     8401 ggttgaaaga tcagtcacca ggttattaca aattagaaga tttattaatg gacaaagggg
     8461 tgtaaaaaac gtggaagctc aagaaatcat ccgctacatt caaacggcat ctaaaaagac
     8521 gcctgtgaaa gtctatctga atgtaaccga gccaatcgaa tttaaagaaa gtaaagtttt
     8581 tggtgaagga agcagcttcg ttgtttttgg tgactatgag acgattgctc cggttttaga
     8641 agctgaatca gaaaaaatca ttgaaatcga aatcgaaact gctgcaagat acagcgcagt
     8701 tcctttgcta gatattaaaa aaattaatgc tcgtatcgaa ccaggtgcta ttatcagaga
     8761 tcaagtgtca atcggcaaca atgccgtgat catgatggga gcgattatca atattggtgc
     8821 agtaatcggt gaaaacacga tgattgatat gggtgctgtc ttaggtggac gagcgacagt
     8881 gggcaaaaac tgccatattg gtgcaggagc tgtcttagca ggtgtgatcg aaccagcatc
     8941 ggccaaaccg gttatcgtag aagacggcgt actggtaggt gcgaatgcag tgattgttga
     9001 aggtgtccat atcggaaaag atgcagtcgt ggcagcagga gcagtggttt tagaagatgt
     9061 ggcagcagaa actgttgtcg gtggaatacc tgcacgtgta ttaaaaataa gtgatgatca
     9121 gacaaaagaa aatacagcat tgattgctgc gttacgcgaa ttatagagga gatggagaaa
     9181 aatgcgcgaa atagatacct gtattgtggg ggcaaccgga ttagtcggcc aaacgatgct
     9241 caaagtgtta gaagaatatg attttccagt aggacgattg aaattattag cttcaaaacg
     9301 ttcagccggt aaagtttgtg tattcaagaa aaagaaacac actgtacagg aattgacaga
     9361 aacttcattt gaaggatatg atttagcgct attttctgca ggtgcttctg tatccaaaga
     9421 gtttgcgcca atcgcacgaa gtcagggact atttgtcata gataattcct cagcatggcg
     9481 ggaagattcg gatattccat taatcgttcc agaggtcaat ctggaagact atacattgaa
     9541 tcggctgatt gcaaatccaa attgttcaac cattcaagcg gtacttccgc ttaaagcttt
     9601 acaagaagcc tttggtatcc agcgagtcaa ttattcgacc tatcaagcag tttctggttc
     9661 cgggcaaaaa ggcattgaag atcttcatcg tacgcaaaat gacgaggaac cagttttgta
     9721 tccttataat attagccaaa cggtgattcc ggaaatcgat cagcctttgg aaaatgggta
     9781 tacaaaagaa gaacagaaaa tgataaatga gacccgtaag attctgcatc agcctgcttt
     9841 gccagtatca gcaacctgcg tacgtgtgcc aatcgaaaat ggacatggag tctctgtggc
     9901 agttcaactg caaaaagagt ttacgacgga agaaattaga gagtgtctca gccagtttcc
     9961 agggattcaa ttagaagatg atctagcagc acataaatat ccgacgagca ttcttgctag
    10021 aggaacagat atggtttatg ttgggaggat cagaaaagac acttctttag agaacggatt
    10081 gttgttctat acgactgccg ataacatacg caaaggagcc gctgcgaatg ccgtacagat
    10141 tgctgcagct ttaatgcaga aaatagcgga ggtggcaaga tgagtaatac gctgaaagta
    10201 gcgaaattcg gcggaacatc gatgtctcat gaagagcaat tcaaaaaagt ccgtacaatt
    10261 gttctttcag atcccaatcg ccaagtgatc gttgtttctg ctttaggcaa acgtacgtca
    10321 gatgatgaca aagtaacaga cttactttat ttgatttatg cttaccttca gcatcatgtt
    10381 gattggacac ccctttggaa aaggatttgt gatcgtttca ttcaagtaag agatgttctt
    10441 gccctgcagt tacctattga agatgaacta gcacgcatac agaaacaact ggaagacgaa
    10501 aagataactg aagattattt agtaagtaga ggtgaatatc tgactgctca actgatggct
    10561 gagtatcttg gttaccagtt tattgacgca aaagacctga ttttctttga ctatgatggg
    10621 aaaatcgatc aggaaaaaac agcacaggaa atcacaaaag catttaaaag atatccgaaa
    10681 atggttgttc cagggtttta cggggcgaac cctgcaggaa aagaaaaatt attgggccgt
    10741 gggggaagcg acattaccgg cgcgatactg gcgaagatgt tgcaagcgga aagttatgag
    10801 aattggacgg atgtttcagg aatcatgatg gctgatccgc gaatcatcga tcatcctaaa
    10861 atcatcgagg aaatctcttt tagagaactg agagagatgg cttatatggg ggctaacgtt
    10921 cttcatgaag cagctgtttt cccagttcaa gaggctgata tccccatcca aataaaaaat
    10981 accaatgatc ctttcgctca agggacaaaa atatcgaatc acgaaataga aaaggaaaat
    11041 ggactgacag gaatagctgg acgcaaggat tttctttcca tcactttatt caaacgtcat
    11101 atgtccgatg aaatcgggtt tatctggaaa gcaatgagca tttttgctaa acatgagata
    11161 tcaatcgaac atattccttc agggatcgac aatatcggag tgatcgtctc agcagaagcg
    11221 attgccgata agttatttct catcacgaaa gaattaaaag aaacacttgg cgtggaagaa
    11281 atcgtcgtga tcgaagactt agctttgatc tctgtcgttg ggggtccgca taaagaattg
    11341 attggattat ctgggaaagt gttatcgata ttgaacaaat tagaaattcg cacatcgatc
    11401 ttatcacaag gagcacagga gttgaatctg atcatcggtg taccgaataa tcaatatgaa
    11461 acagtagtga agggtatcta tgaagggatg gtgaatacgg atgctgaaag aatatcgaat
    11521 ggcactccat caaattcctg aaatcgggtt tcatgaattc aagacaaaaa aatatttata
    11581 tgaacaagta aaaaacagcg aggccgttat ccatgaaatc ggcgaaacag gactactcct
    11641 ttattttgat aatcagcaag aagaaacgat tgcttttcga acagatatcg atgcactgcc
    11701 agtcaaagaa gaaacgaatc tctcttttgc ttctaagcat gaaggttata tgcatgcatg
    11761 tggtcatgac ggacatatgg cgatgctttt agggttgact gactttataa ctaaacacat
    11821 tgaggatctt atttataatg tagtactgat ctatcagcca tcagaagaaa tttccggtgg
    11881 cgcacaaagc gttattcagt caggattgtt ggataaatat gaagtacaag caatatttgg
    11941 ctttcatcta tggcctggac tagctaaggg agaagttttc tctcgaccag gacctttgat
    12001 ggcacaaagc agtgaaacag acattatcat taaaggccag tctgcacata ttgcttctag
    12061 tgaaaaagga atcgatagtc tggaggcagc tgtacgattt ttgaagaatg tttatgattt
    12121 tgaccggcaa ttaccggcag agtggaatca tctaatgaaa tttggccaaa tccaaggtgg
    12181 aacgatccga aatgttttag ctggagaagt tattgtatcc ggaagtatcc gttcttacag
    12241 ttcagatatg caaaattatt tgaagagggg attagaccat ttagcagaac agtttcactc
    12301 tacagctact atttcttttc gctataatga cggctatcca gctgtaatca accatagagg
    12361 cttatatgca gcactgttag attcaaacaa actacatgaa ttagatgctc cagttcttca
    12421 agccgaagat tttggcatat atacgcaaca atatccatgt gtatttttct ttttaggtgt
    12481 cggtgatacc cctgctttac atgatccgac gttcgatttt gatatggatg ttttagaaaa
    12541 tggtgtagaa tggtacaaaa cgattctttt tacagaaaat cttcttgtaa aaatcgatag
    12601 cagttcaaaa gaggagcgag taaataatga tgaatttatc caatcgattt agtcctaggc
    12661 tttctagaat agaagtatca aaaatacgac aattcgatca gcaaatatcg tcgataccag
    12721 atgtgatcaa actcaccctg ggagaaccgg attttccaac tcctgaacat gtcaagcaag
    12781 caggaatagc agcgattgaa gaagactttt ctcactatac cggaatgaga ggattagagg
    12841 aactgcggga agcggcttgt atatttcagc aacagcgtta tggattaact tatgatccgc
    12901 aaacggaagt tttgacgaca gttggtgcaa cggaagcgat tgcctctgcg ttgttatctg
    12961 ttttggaaga aggagacaag gttcttattc cagcgcctgc ttattcagga tatcagccat
    13021 tagtggaact agctggtgct gaattgatcc cgatagatac ttctgacaca gggtttgtct
    13081 gtcagccgga acaatttgaa cgagcatttg aacaatatgg atcagctgtc aaagcagtca
    13141 ttttaaacta tcctaacaat cctactggga cgacattgtc tgcaaaacaa ttgaaagcaa
    13201 tcgctgaggt tttaaaaaaa tatccggtat ttgttataag tgatgaagta tatgctgaat
    13261 tgacttatag tggaacgcat atgtccatag ctacttatct tccagaacaa acaatcgtga
    13321 taagcgggtt atccaagtca catgcgatga ctggttggcg agtgggcttt atttttgctc
    13381 aaaaagccct tattgacgaa ctaattaaag tccatcaata tctggtgact gccgctacaa
    13441 cgatgtcgca aaaagctgcg gctgaagcgc taataaatgg ggtgaaagat agcgagaata
    13501 tgaaagagca atatcaaaca cgaagagact atctggtcca gcaattggcg cctttaggat
    13561 ttgaagtgac ccagccaaac ggtgcatttt acttgttttg caaactccca gctgccattc
    13621 aaactgactc ttggcagttt tgtgtagaat tagcggaaca ggcaaaagtt gcgtgtatcc
    13681 caggaattgc atttggccca gaaggagaag gttatatccg gatttcttat gctagcagca
    13741 tggaaaaatt acatgaggcc tgcaaacgga tcaaagactt tttaacagaa cagtgattca
    13801 tagattttat caaaaaaaca atcgttaatt ttgcggtata ttctgcaagg agacgattgt
    13861 tttttaaatt tagttcaaat gaacgcgttt cttttgattc ataactaatg taatgttaag
    13921 tttaaattgt ttagaatgat tttaaaagaa tattcaagga ggtttcatca atggaaaaaa
    13981 tcaaagttgt cattgtaggt gcatctcatg gagggcatca atcgatcttg gaactattga
    14041 cacgatacgg tgaaaatgta gatatcacgc tatttgaagc aggagactat atttccttca
    14101 tgtcatgtgg tatggagctg tatttagaag acaaggtaac agatgtaaat gatgtacgta
    14161 atttcagacc agaaaacttt ccgcaatcca atgttca
//
LOCUS       DAZKKZ010000067        14101 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.069, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000067 DAZKKZ010000000
VERSION     DAZKKZ010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14101)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14101)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14101
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.069"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(161..2158)
                     /gene="tkt"
                     /locus_tag="ACG8LA_002306"
     CDS             complement(161..2158)
                     /gene="tkt"
                     /locus_tag="ACG8LA_002306"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004802 - transketolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HFQ0204585.1"
                     /translation="MFDKIDQLGVNTIRTLSIEAVQKANSGHPGLPMGAAPMAYALWT
                     KHLKVNPTTSKNWADRDRFVLSAGHGSAMLYSLLHLAGYQVTIDDLKQFRQWDSKTPG
                     HPEVHHTDGVEATTGPLGQGIAMAVGMAMAEAHLAATYNKENFNVMDHYTYAICGDGD
                     LMEGVSQEASSMAGHMKLGKLIVLYDSNDISLDGPTSKAFTENVGARYEAYGWQHILV
                     KDGNDLEAISKAIEEAKAETDKPTLIEVKTVIGYGAPKEGTSAVHGAPLGEDGIKMAK
                     EVYGWEYPDFTVPEEVAARFHQTMIEEGQKAEDAWNEMFANYKKAYPELAQQFEDAFD
                     GKLPENWDAELPTYEVGSSQASRVSSKEVIQELSKAIPSFWGGSADLSGSNNTMVAAD
                     KDFTPEHYEGRNIWFGVREFAMASAMNGIQLHGGTRIYGGTFFVFVDYLRPAVRLAAI
                     QHTPVVYVLTHDSVAVGEDGPTHEPIEQLASVRCMPGVQVIRPADGNETRAAWKVAME
                     TTDAPTILVLSRQNLPVLPSTKEVADEMVKKGAYVLSPSQGETPEGILIATGSEVDLA
                     VKAQKELAEKGKDVSVVSMPSFDLFEKQSSEYKESVLPKSVKKRVAIEAAASFGWERY
                     VGTEGATITIDHFGASAPGTKILEEFGFTVENVVNTYNQLS"
     gene            complement(2260..2511)
                     /locus_tag="ACG8LA_002307"
     CDS             complement(2260..2511)
                     /locus_tag="ACG8LA_002307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HFQ0204586.1"
                     /translation="MLSPEKIERINELARKKKENGLSKAEEQEQINLRKEYLEAFRSG
                     MRHHIEGMKVVDPEGNDVTPEKLKEIQKKKGLHNRNDNF"
     gene            2658..3281
                     /gene="lexA"
                     /locus_tag="ACG8LA_002308"
     CDS             2658..3281
                     /gene="lexA"
                     /locus_tag="ACG8LA_002308"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0009432 - SOS response [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor LexA"
                     /protein_id="HFQ0204587.1"
                     /translation="MARQTESRQIEVLRYIHEQVTQKGYPPTVREIGEAVQLSSTSTV
                     HGHLARLEKKGFIQRDPTKPRAIELTKQGLEKIGIRPTTIPVLGVVTAGEPILAVEDA
                     SDFFPIPPNLSSEEGSLFMLTIRGDSMINAGILDGDNVIVRKQETAQNGDIVIAMTAE
                     DEATCKRFYKEKNFFRLQPENDLLEPIILDQVSILGRVVGLYRSHIY"
     gene            3461..3679
                     /locus_tag="ACG8LA_002309"
     CDS             3461..3679
                     /locus_tag="ACG8LA_002309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204588.1"
                     /translation="MKSMRRLGLVLTVLFLGIIIGNFGIRPALLVFVPLFTLWFMLWD
                     EKKYRQSERRRIHEDHFYHEPYYRSRQS"
     gene            complement(3968..4480)
                     /locus_tag="ACG8LA_002310"
     CDS             complement(3968..4480)
                     /locus_tag="ACG8LA_002310"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003999 - adenine
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0006168 - adenine salvage [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HFQ0204589.1"
                     /translation="MDLKDYIASIPDYPSKGIVFRDISPLMADGDAYREATKQIVNYA
                     KEKRIDMVVGPEARGFIVGCPVAYELGVGFAPVRKKGKLPRETIEVTYGLEYGTDTLT
                     LHKDAIKPGQRVLICDDLLATGGTIKATIELIEQLGGVVVGCAFLIELMDLHGRDKIK
                     GYDIITLMEY"
     gene            complement(4494..6791)
                     /gene="recJ"
                     /locus_tag="ACG8LA_002311"
     CDS             complement(4494..6791)
                     /gene="recJ"
                     /locus_tag="ACG8LA_002311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008409 - 5'-3' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HFQ0204590.1"
                     /translation="MRQANFDWKLSETEPSESFLQMIRELKLSPFVGKLLWQRGYHEE
                     KDINRFLHPKEQELHDPYLIHDMDKAISRIQEAVISGEKILVYGDYDADGITSATVMK
                     ETLELLGAEVEVFLPNRFEHGYGPNQSVYQEKIEEGIQLIITVDNGVAGNDAVAYAQQ
                     AGVDVIITDHHELPENLPDAYAIVHPRHPAGHYPFPDLAGVGVAFKVASALLEEPPAE
                     FLDLVAIGTIADLVSLTDENRILVSLGIDAIHHSERIGLQALFEESGVKMRDADETTI
                     GFSIAPRLNAIGRMGDPRPAVSLLATFDEEEASVQAKKLNEINEERKAIVEQITQEAL
                     AMVNKENHIHLLVNRGWHEGVLGIVAGKIMNETGKPTLVLTLKEDGSAKGSGRSIEAL
                     NLFEMLDQMRDLFTYFGGHHAAVGLTMPSENVTILQEKMNQYIVDHQIDLMRGPELRI
                     DEVLLPNEVTVERIDELKLLAPFGTDNPLPQFLFRQVQAENIKRIGANQQHLKFVLSD
                     ASSQLDAVAFGFGTQEEELLNNQVDVVGKLSINEWNGRKKPQLMVSDFSVGGLQVFDW
                     RAKRFREQSRTSEGSLYLAFDSSTLKFVPEIIQEAAIVFEGLDSVKAIIEKRKPNSLV
                     VMDCPDDLADLKEVFRSYSFNRVYLMGISPDEAYLNGVGTREQYAKLFKLIHSQERID
                     IRHKIKAIAQYLRIPEKLLIFMIQVFFELKFVTIENGVLQKVASPESHPLTESRLYQR
                     RLNKIKVEEFLLLSDIPTIKKWLTT"
     gene            complement(6933..7376)
                     /locus_tag="ACG8LA_002312"
     CDS             complement(6933..7376)
                     /locus_tag="ACG8LA_002312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide assembly protein LapA
                     domain-containing protein"
                     /protein_id="HFQ0204591.1"
                     /translation="MKELKKQSNVILGFVLVLIIVLFAVLNNKNVPVSFGFTSFSAPL
                     ILVIIGSALIGALIVFLTASATLWQQKKQIKQLTQEMSEYQTELQKKIEEAKEEQQRE
                     FRNERAELEAAYQAELQAKTAQISQLKAPEEQKTQSPKQSFNYFD"
     gene            complement(7377..8165)
                     /locus_tag="ACG8LA_002313"
     CDS             complement(7377..8165)
                     /locus_tag="ACG8LA_002313"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HFQ0204592.1"
                     /translation="MNLEDKVVLVTGSSGGLGAQICYEAAKQGAIVISCARRMAFVEG
                     VRDECRRLSGKEAYAFKVDVSNPESVDELYEKVMEEVGRVDILVNNAGFGIFEDFLTF
                     DLGKAYDMFEVNILGMMVLTQKFAIDMAERRQGHIINIASMAGKMATAKSTVYSATKF
                     AVLGFSNALRLELKPLGVAVTTVNPGPIETNFFDKADPSGSYLEKVGQIVLEPAKLAK
                     MIVRNMRHPKREINQPFILEVASKFYTLFPTIGDYLASGIFNKK"
     gene            complement(8162..9103)
                     /gene="rnz"
                     /locus_tag="ACG8LA_002314"
     CDS             complement(8162..9103)
                     /gene="rnz"
                     /locus_tag="ACG8LA_002314"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016891 - RNA endonuclease activity,
                     producing 5'-phosphomonoesters [Evidence IEA];
                     GO_process: GO:0042780 - tRNA 3'-end processing [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HFQ0204593.1"
                     /translation="MELQFLGTGAGVPAKHRNVTSIALKLLDERNEVWLFDCGEGTQM
                     QILRTTIRPRKIGKIFITHLHGDHIFGLPGLISSRSFQGGDTPLEIYGPKGIEEYIKV
                     SLGISQTRLSYPLKFIELNETAPIFTDQQFSVYTKKLNHGIDSFGYRVVEHDHKGELQ
                     VDRLKELGIPAGPLYGKLKQGETIQLEDGRTINGKDFVGPDKKGRIVTILGDTRKTHN
                     SVVLAENSDILVHESTFNKDEARMAHNYFHSTTHQAAEVAKEAQAKRLLLTHISARYL
                     GKAALELEKEAQEVFENTTIMKDFDSIEIPFREEEEA"
     gene            complement(9280..9867)
                     /locus_tag="ACG8LA_002315"
     CDS             complement(9280..9867)
                     /locus_tag="ACG8LA_002315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1269 domain-containing protein"
                     /protein_id="HFQ0204594.1"
                     /translation="MSKRVIILNFQVESQAYQAFSEIKKLHAVRSIKGEQMAVVSHDP
                     NGTHQFKIEDFIDFTGNNKSSTGGLIGMLVGVLGGPLGILLGWFAGGMIGATQDAKEI
                     KDAQTVFDFVGNKIGEGATGLILIADEEDNRPLNQLVMMELGGEITRLDYEDVEKDVH
                     DAKEAENHAKEAAQKTWKDKHPQTSNDNESSGSSN"
     gene            complement(10088..11401)
                     /gene="obgE"
                     /locus_tag="ACG8LA_002316"
     CDS             complement(10088..11401)
                     /gene="obgE"
                     /locus_tag="ACG8LA_002316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003126661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HFQ0204595.1"
                     /translation="MSMFLDQVTIDVKAGKGGDGMVAFRREKYVPDGGPAGGDGGRGG
                     DVILIVDEGLRTLMDFRFNRHFKAQPGENGMSKGMHGRGSEDTYVKVPQGTTVRDAET
                     GALLGDLIENGQTLVVAKGGRGGRGNIRFASPRNPAPEIAENGEPGQERKIELELKVL
                     ADVGLVGFPSVGKSTLLSVISSARPKIGAYHFTTLVPNLGMVTTSDGRSFAAADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHVIDMSGMEGRDPYEDYLAINKELSTYNLRLLE
                     RPQIIVANKMDMPDAPENLVKFKEQLNKEKEDEFADDIPVFPISGVTRQGLDALLNAT
                     ADLLEVTPEFPLYEEELEEETVHYGFNPEGPEFQIDRDSDATWILSGEKIEKLFQMTN
                     FDHDETVMRFARQLRGMGVDEALRARGAKDGDLVRIGEFEFEFVE"
     gene            11689..12699
                     /gene="gap"
                     /locus_tag="ACG8LA_002317"
     CDS             11689..12699
                     /gene="gap"
                     /locus_tag="ACG8LA_002317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HFQ0204596.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIKEVSDDIEVVAINDLTSPTMLAQ
                     LLQFDSTHGTYPGTVTATEDSIVVDGEATRVYAEPDASKIPWAKENGVDIVLECTGFY
                     TSEEKAKAHLDAGVKRVVISAPAGAMKTIVYNVNDDTLDENDKIISAGSCTTNCLAPM
                     AYFLNNEFGIEVGTMTTVHAYTSTQMLLDGPVKGGNLRAARSAADNTIPHSTGAAKAI
                     GLVIPELQGKLQGHAQRVPVVDGSLTELVSVLKTKVTADQVNEAIKKHTVDNPSFGYD
                     DRQIVSSDVIGTTQGSIFDPTQTEVTTAGDFQLVKTVAWYDNEYGFTCQMIRLLEKFA
                     NL"
     gene            complement(12784..13719)
                     /locus_tag="ACG8LA_002318"
     CDS             complement(12784..13719)
                     /locus_tag="ACG8LA_002318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFQ0204597.1"
                     /translation="MKLWMKILLGVALALIVALVFAGNYFYNYAVVPSEKDFLDEDTP
                     GTTQTSKETDAHKWFSSKENRSDWTITSKDGLKLSAIYLPAETKSEKTALVAHGYMGN
                     AETMTNYAKMFHDMGYNVLVPDARGHGKSEGDYIGFGWPERKDYVQWINKVLENNGKS
                     QEIVLYGVSMGAATVMMTSGEKLPDNVKAIIEDCGYSSVHDELAYQLDDMFSLPAFPL
                     MQVTSLVTKVRAGYFFGEANAVEQLKKNQRPMLFIHGDEDTFVPFEMLDKVYRATKGP
                     KEKYVVKGAEHAEAYKTDPEKYQQVVQQFLSQYVH"
     gene            13905..>14101
                     /locus_tag="ACG8LA_002319"
     CDS             13905..>14101
                     /locus_tag="ACG8LA_002319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0204598.1"
                     /translation="MTYKHLTIDELTMIESYYLQHNKPVEIANRMGRAIQTIYNVVNK
                     FKQGKTTLDYWHQYKENKKKCG"
BASE COUNT         3932 a         3142 c         2485 g         4542 t
ORIGIN      
        1 tcaagaaaca caaactaatc cgaagaattc tttgttttgt catttaaatg taacatagcc
       61 gaaaacgaaa agtaatattg atttattctt ctaacacata aagaacagct gtctccaact
      121 tgcagacagc tgttcttatc agtcaaacaa ttgcttggat ctatgatagt tgattgtacg
      181 tattcacgac attttctact gtaaatccaa attcttctaa aattttagtg ccaggggcag
      241 atgcaccgaa atgatcgatt gtaatcgttg cgccctctgt tcctacgtag cgttcccatc
      301 caaatgatgc agcagcttcg atagccacac gtttcttcac tgatttagga agtacacttt
      361 ctttatattc agaagattgt ttttcaaaga ggtcaaagct tggcatagaa acaacagaaa
      421 catctttgcc tttttcagcc aattcttttt gagctttcac agccaaatca acttcagaac
      481 ctgttgcaat caaaatacct tctggtgttt ctccttgtga tggagaaaga acatacgcgc
      541 cttttttcac catttcatct gctacttctt ttgtagaagg caatactgga aggttttgac
      601 gactcaatac aaggatagta ggcgcatctg ttgtctccat cgctactttc caagcagcac
      661 gtgtttcatt tccgtctgcc ggacgaatca cttgaacacc aggcatgcag cgaacagatg
      721 ctagttgttc aatcggttcg tgcgttggtc cgtcttctcc gacagcaacc gagtcatgtg
      781 ttaagacgta aacaacagga gtatgttgga ttgctgctaa acgaactgct ggtcttagat
      841 aatcgacaaa gacaaagaat gttccaccgt agatacgagt tccgccatga agttggatac
      901 cattcatagc cgaagccatt gcaaattcgc ggacaccgaa ccagatgttg cgtccttcat
      961 aatgttcagg agtgaaatct ttatctgcag ccaccattgt attattggaa cctgacaagt
     1021 ccgctgaacc accccagaag cttggtatag ctttcgataa ttcttggatg acttctttac
     1081 ttgaaacacg gcttgcttga ctgcttccaa cttcataagt tggcaattct gcatcccagt
     1141 tttctggtag tttgccatca aaagcatctt caaattgttg tgctaattca ggataagctt
     1201 ttttataatt ggcaaacatt tcattccatg catcttcagc tttttgtcct tcttctatca
     1261 tcgtttgatg gaagcgggca gctacttctt ctggaacagt gaaatctgga tactcccaac
     1321 cataaacttc tttagccatc ttgatgccat cttcaccaag aggagcacca tgaacagcag
     1381 atgttccttc tttaggagca ccatagccga tgactgtttt tacttcgatc aatgttggtt
     1441 tgtctgtttc agcttttgct tcttcaatcg ctttagagat tgcttctagg tcatttccgt
     1501 ctttcactaa gatatgttgc cagccatatg cttcatagcg agcaccaacg ttttctgtga
     1561 aagcttttga agttggaccg tctagtgaaa tatcgtttga atcgtataaa acgatcaatt
     1621 tccctagttt catatgacct gccatcgaac ttgcttcttg agatacccct tccatcaagt
     1681 ctccgtcacc gcatattgca tacgtatagt gatccatcac attaaagttt tctttgttat
     1741 acgttgctgc aaggtgcgct tctgccattg ccataccgac agccattgca atcccttgtc
     1801 ctaatggccc tgtagtggct tctacaccat ctgtatgatg tacttcagga tgtcctggtg
     1861 ttttagaatc ccattgacgg aattgtttca aatcatcgat tgtcacttga tagccagcta
     1921 aatgaagcaa gctatacaac attgctgacc catgtcctgc cgaaagaacg aaacggtcgc
     1981 ggtcagccca gttttttgat gtcgttggat ttactttcag gtgttttgtc cataacgcat
     2041 atgccatagg tgctgcgccc atcggcaatc caggatgtcc tgagtttgct ttttggactg
     2101 cttcaatact taatgtacga attgtgttaa cgccaagttg gtcaattttg tcaaacaaaa
     2161 taacccctcc tattaattta ggtttttttt acctttattt cttacacttt cattctataa
     2221 gatgtcacac gaaaaagcaa tctttttcag tattttttac taaaagttgt catttcggtt
     2281 gtgtaagcct tttttctttt ggatttcttt taatttttcc ggggtcacgt cattgccctc
     2341 aggatcgacg actttcattc cttcgatatg atgacgcata ccggaacgaa aagcttccaa
     2401 atactctttg cgcaagttga tttgttcttg ttcttcggct tttgagagac cattttcctt
     2461 ctttttacgt gcaagttcat tgatccgctc tattttttca ggtgacagca tgctcagccc
     2521 tccttttact ctccttcata ttatataaaa actgaaaaaa aaacaactag ataaactaaa
     2581 taaaatacga acattcgttt gatttagcgc tttttatatg gtactattta tttatcaagt
     2641 gaaagaaggt gtaccttgtg gcccgacaaa ctgaatcaag acaaatcgaa gtcttacgat
     2701 atatccatga acaagtaacc caaaaaggat acccgccgac tgtccgtgaa atcggggaag
     2761 ctgttcagct ttcttctact tctactgttc acggtcatct tgcacggctt gaaaaaaaag
     2821 ggtttatcca aagagatccg acgaaacctc gtgcaatcga gttgacaaaa caaggtttag
     2881 aaaagattgg gattcgtcca acaactattc cagtacttgg cgtcgtaaca gctggagaac
     2941 ccattttagc agtagaggat gcttcagact tctttccaat ccctcctaat ctttcttccg
     3001 aagaaggcag tctctttatg ctgacaattc gtggagatag tatgatcaat gctgggatat
     3061 tggatggtga caacgtgatc gttcggaagc aagaaactgc tcaaaatggc gatattgtca
     3121 ttgcaatgac tgccgaggac gaagcgactt gcaaacgatt ctataaagaa aaaaactttt
     3181 tccgtctgca gcctgaaaac gacttgctcg aaccaatcat cttagatcaa gtatctatat
     3241 taggacgagt agtaggactt tatcgtagtc atatctatta attgctacta attaaaagaa
     3301 aactttttaa aaagagtttg agacgttggt ctcaaactct tttttcgccc gggttcttct
     3361 tctttcaaat ttttatcact tccctcttta caaaccgaac aaatattcgt atactaaata
     3421 tacgaacaat tgttcgcata aattaaagag gtgagaattc atgaaatcaa tgagacgtct
     3481 tggcttagta ttaactgttt tgtttttagg tattattatt ggtaatttcg gcatacgtcc
     3541 agctttactt gtgtttgttc cgttatttac tttgtggttc atgttgtggg atgaaaagaa
     3601 gtaccgtcaa tctgagcggc gcagaattca tgaagatcat ttctatcatg agccctacta
     3661 cagatccagg caatcataat aaggattgac tgctaattat tcaaaagaca agaagttaaa
     3721 cttttacggg ggtgtgacaa aaatcggtca catccttttt ttcgaataaa cggtgttcta
     3781 aagccagttt ttcggtatta agtcaaattg cggaaaaagt gattttttaa acttctactg
     3841 gtctttgctt gtttccattt ataaaaaaat agcgaccctc aaaagtcaga tagagaatct
     3901 gacttttgag ggtcgcttta aaatcgcttc tttaagaata acatcaagaa tagcttcttt
     3961 tttctgctta atattccatt aatgtaatga tgtcatatcc tttgattttg tcgcgtccat
     4021 ggagatccat caattcgatc aaaaatgcgc agcctacgac tacaccgcct aattgttcga
     4081 tcagttcgat cgtcgctttg attgttcctc cagtagctag caaatcgtca caaatcagca
     4141 cacgttgacc tggtttaatg gcatccttat gcaatgtcaa tgtatctgtt ccatattcta
     4201 atccataagt cacttcgatg gtttctcgag gtaacttccc ttttttgcgg actggggcaa
     4261 aaccgactcc taactcataa gcaacaggac atcctacgat gaatccacgg gcttctggcc
     4321 caactaccat atcaattcgt ttttcttttg cataatttac gatttgttta gtagcttccc
     4381 gataagcgtc accatctgcc atcagtgggg aaatatctcg aaacacaatt ccttttgacg
     4441 gatagtcggg aatactggca atataatctt ttaaatccac tctttgtttc ctcctaggtt
     4501 gttaaccatt tctttatggt aggaatatcg ctcaaaagca aaaattcctc aactttgatt
     4561 ttattgagcc gtcgctggta taatctgctc tcagtcaaag gatgactttc tgggctagcg
     4621 actttttgta aaacaccgtt ctctattgta acaaatttca attcaaaaaa cacctgtatc
     4681 ataaaaatta ataatttttc agggatacgc aaatattgag ctattgcttt tattttatga
     4741 cgtatatcaa ttcgttcttg agaatggatc aatttaaaca attttgcgta ctgttctctt
     4801 gtgcctaccc cattcaaata ggcctcatca ggtgaaatcc ccatcagata aacacgattg
     4861 aatgaataag accgaaaaac ttctttcaga tccgctaaat catctggaca atccataaca
     4921 actagagagt ttggttttct tttttcaatt attgccttta cagaatctag tccttcgaaa
     4981 acaatcgcag cttcctggat aatctcaggc acgaatttca acgtcgaaga atcaaatgct
     5041 aaataaaggc taccttccga cgttcggctc tgttcacgga aacgttttgc ccgccaatca
     5101 aatacttgca gaccacccac agaaaaatca gataccatca gctgcggttt cttacgcccg
     5161 ttccattcat tgatcgaaag ctttcctacc acatctacct gattattcag cagttcttct
     5221 tcttgagtac caaaaccaaa agcgaccgca tcaagctgac tcgatgcatc ggaaaggaca
     5281 aatttcagat gctgttggtt tgctccgatt cttttgatat tttctgcttg gacttgtcga
     5341 aataaaaact gaggcaaagg attatccgta ccaaatggcg ccaatagttt cagctcatca
     5401 attcgctcta ctgttacttc atttggcagc aatacttcat caattctcaa ctcaggccct
     5461 ctcatcaagt caatttgatg atcgactata tattggttca tcttctcctg tagtatagtg
     5521 acattttcac ttggcatcgt taaaccgact gctgcatgat gtcctccgaa gtaagtaaat
     5581 aaatctcgca tctggtcaag catttcaaaa agattcaagg cttcaatact acgtccagat
     5641 cctttagctg atccatcttc ttttaaagta aggacaagcg ttggtttacc cgtttcattc
     5701 attattttcc cagcaacaat gcccaaaacg ccttcatgcc atcctcggtt taccaataga
     5761 tggatatgat tctccttatt gaccatcgct aatgcttctt gtgttatctg ctctacgatt
     5821 gcttttcttt cttcattgat ctcattcaat ttttttgctt gaacggatgc ttcctcttca
     5881 tcaaacgtcg caagtaacga gacggcagga cgtggatcgc ccatccgacc gattgcattt
     5941 agtctgggag caatcgaaaa accgatcgtt gtttcgtctg cgtccctcat ttttacgccg
     6001 ctttcttcaa atagcgcctg aagtcctatc cgttctgaat gatgaatggc atcgattcct
     6061 aatgaaacaa ggattcgatt ctcatcagtc aatgaaacta aatcggcgat cgttcctatc
     6121 gctactaaat ccaaaaattc tgcaggcggt tcttccaata atgcagaagc tactttgaat
     6181 gctactccga ctcctgccaa atctggaaat ggatagtgcc ccgctggatg acgagggtga
     6241 acaatcgcat aagcgtctgg taaattctca ggtagttcgt gatgatctgt aatgatcacg
     6301 tctacaccag cttgctgagc gtatgctacc gcatcatttc ctgctacccc gttatcaaca
     6361 gtgatgatca actggattcc ttcttcgatc ttttcttggt ataccgattg gtttggtcca
     6421 tacccatgct caaatcgatt tggcaggaat acttctactt ctgcaccaag taattccagt
     6481 gtttctttca ttaccgttgc actggtgatc ccatctgcgt cataatcacc gtaaacgagg
     6541 attttttctc cactgattac agcttcttgg attcggctga ttgctttatc catatcgtgt
     6601 atcagatacg gatcatgtaa ttcttgttcc tttggatgta aaaatcggtt gatatccttt
     6661 tcctcatggt aacctctttg ccacagtaac ttaccgacaa atggagataa tttcagttca
     6721 cggatcattt ggagaaagga ttcagaaggc tctgtctcgc ttaacttcca atcaaaattt
     6781 gcttgtctca ctttctcact cctaacttag ttattatagc aaaggaaatc agcaaaaaaa
     6841 agcagaaaga aagaataaaa acagatcaga tccgctagac agatgttcag caggacctga
     6901 tcttttgtac gaccatttat gaaatatccc tattagtcaa aataattgaa gctttgtttg
     6961 ggcgattgag ttttttgttc ttccggcgct ttcaattgac tgatttgtgc ggttttcgct
     7021 tgtaactccg cctgataagc agcttccaac tccgcacgtt cgtttctaaa ctcgcgttgc
     7081 tgttcttctt ttgcttcttc aattttcttt tgaagttctg tttgatattc tgacatttcc
     7141 tgagtcagct gtttgatttg ctttttttgc tgccatagtg ttgccgaagc agtcaaaaat
     7201 acaatcagtg caccaatcag cgcagaaccg atgatcacta agatcaatgg cgcagaaaag
     7261 gaagtgaagc caaaacttac aggaacattt ttattgttca atacagcaaa aagaacaata
     7321 atcaaaacta aaacaaatcc aagaatcaca ttgctttgct ttttcaattc cttcacctac
     7381 tttttgttaa aaattccgct ggctaaataa tcaccaatcg ttggaaacag cgtataaaat
     7441 tttgatgcaa cttctaaaat aaacggttga ttgatttccc gttttggatg tctcatattg
     7501 cggacgatca tttttgccaa cttggcaggt tctaaaacga tttgtccgac tttttccaaa
     7561 tagcttccgc ttggatcagc cttatcgaag aaatttgtct cgattggacc tggattcact
     7621 gtcgtaacag ctacgccaag tggtttcaat tctaatcgca aagcgttgga gaagccaagg
     7681 actgcaaatt tcgtggcaga ataaaccgtt gattttgcag ttgccatttt tccagccata
     7741 gaggcgatat taatgatatg accttgtctt ctttctgcca tatcgatcgc aaatttttgt
     7801 gtcaaaacca tcattcctaa gatgttgact tcaaacatat cgtatgcttt tccaaggtcg
     7861 aatgtaagga agtcttcgaa aatcccaaaa cccgcattgt ttaccagaat atcgacgcgc
     7921 ccgacttctt ccatcacctt ttcatataat tcgtccacgc tttcaggatt gctgacgtct
     7981 accttgaaag cataagcctc tttgccgctc aagcgtctgc actcgtctct gacaccttct
     8041 acaaatgcca ttcttcgtgc gcaacttata acgattgctc cttgctttgc tgcttcataa
     8101 cagatttgtg cgcccagacc gcctgaacta cctgttacta aaacaacttt atcttctaaa
     8161 ttcatgcctc ttcctcctcg cgaaatggaa tctcaatgct atcaaaatct ttcataatcg
     8221 tcgtgttttc aaacacttct tgtgcttctt tttcaagctc taaagctgct tttcctaaat
     8281 atctcgcact gatatgagta agtagcagcc gttttgcctg cgcttctttt gcaacttcag
     8341 cagcttgatg agtcgtggaa tggaaatagt tgtgcgccat tcttgcttca tctttattaa
     8401 atgtgctttc atgtaccaga atatcgctat tttccgcaag cacaacggaa ttatgtgttt
     8461 ttctcgtatc gcctaaaata gtcacgattc gtcctttttt atctggacct acgaaatctt
     8521 ttccattgat cgtccgccca tcttctagtt ggatcgtttc accttgcttc agtttgccgt
     8581 acagtggtcc agctggaata cctaattctt ttagacgatc cacctgcaat tctcctttat
     8641 gatcatgttc aaccacacga taaccaaaac tgtcgatccc atgatttagt ttttttgtat
     8701 aaacagaaaa ttgctgatca gtaaaaatcg gggctgtttc atttagctca atgaatttca
     8761 gcggataact taaacgcgtt tgcgaaatac ctaaagagac ttttatgtat tcctctatcc
     8821 cttttggccc gtaaatctct aatggcgtat ccccaccttg aaatgaccgg ctgctgatga
     8881 gcccgggaag tccaaaaata tgatcgccgt gtaaatgtgt aatgaaaatt ttaccgattt
     8941 ttctcggacg aatagtcgtt cgcaaaatct gcatttgcgt gccttcgcca cagtcgaaca
     9001 accaaacttc attgcgctcg tctaaaagtt tcaatgctat acttgtcaca tttctatgtt
     9061 ttgcaggaac acctgcacct gttcctaaaa attgtaattc cataatctac ctgactttct
     9121 ttaagttcct ctttaatttt agggtaaaaa gaagggataa tcaaccgtaa gtcgagaatg
     9181 ggttcaaatt aaaaataacg ttctaaagcg atagcgtttt ctttgaaaat tactataaaa
     9241 acagcagcga acccgtttga gatcctctgc tgttttttat taatttgaag atccagaact
     9301 ttcattgtcg ttggaagttt gcggatgttt gtccttccaa gtcttttgtg cagcttcttt
     9361 cgcatgattt tcagcttctt tcgcatcatg cacatctttt tcgacatctt cataatccaa
     9421 gcgagtaatt tctccgccta attccatcat taccaattga ttcagtgggc gattgtcctc
     9481 ttcatcagca atcaagatca gtcctgtagc tccttcaccg attttatttc ctacaaagtc
     9541 gaacacggtc tgggcatctt ttatttcttt ggcatcttgt gtcgcaccga tcattcctcc
     9601 ggcaaaccat cctaataaaa tccctagcgg accacctaat acaccaacca acattccgat
     9661 taatccaccc gtagaagatt tgttattacc ggtaaagtcg ataaaatctt ctattttgaa
     9721 ttgatgtgtc ccattaggat catggctgac aactgccatc tgttctcctt taatcgaacg
     9781 aacagcatgt aactttttga tttctgaaaa tgcctgatat gcctggcttt ctacttgaaa
     9841 atttaaaatg attactcgtt tgctcattaa aaacgcccct ttcatacctt cttgttattt
     9901 attttacctt taattgaaaa ataagaaaag aaaagcactc tttttttcca ataaaatagg
     9961 gctgtgacaa aagtcgtatc acagctcctt tttccgaata aacggcgttc ttgaagctga
    10021 tcacttctgt cacaacctcc cttaaatctg aatctatatt ttttggtatt tgtttttatt
    10081 tgcttgccta ttcgacaaat tcaaattcaa actcaccgat acgtacaagg tcgccatctt
    10141 tcgcaccgcg tgcccgaaga gcttcatcca cacccatacc acgtaattga cgagcaaaac
    10201 gcatcactgt ttcatcatga tcgaaattcg tcatttggaa taatttttcg atcttctcac
    10261 cagataagat ccacgttgca tctgaatcac gatcgatttg gaactcagga ccttctggat
    10321 tgaatccata gtgtacagtt tcttcttcca gttcttcttc gtacaatggg aattctggcg
    10381 ttacttctaa caaatctgct gtagcattca ataacgcgtc caatccttgt cgagtcactc
    10441 cagaaattgg aaatactggg atgtcatcag caaattcatc ttctttttcc ttgttcagct
    10501 gttctttgaa tttcactaga ttttccggtg catccggcat atccattttg tttgccacga
    10561 tgatttgcgg acgctctagc aagcgtaagt tataagtaga taattctttg ttgatggcaa
    10621 gatagtcttc ataaggatct cgtccttcca tcccactcat atcgatcaca tgtaaaatta
    10681 ctcgtgttct ttcgatatga cgaaggaatt gtgtacccag cccaacacct tgcgaagctc
    10741 cttcaatcaa gcctggcaag tctgctgcgg caaaacttct gccatcactt gtagtaacca
    10801 ttcctagatt aggtacgagc gtcgtgaaat gataagcgcc gatttttgga cgagcagatg
    10861 aaataacgga tagtaaagtc gatttcccga cagatggaaa acctacaagt ccaacgtctg
    10921 ccaatacttt caattctagt tcgatttttc gctcttgtcc tggttcaccg ttttcagcaa
    10981 tttccggtgc aggattccga ggagaggcaa aacggatatt ccctcgtcca ccgcgtccac
    11041 cttttgccac aactagtgtt tgaccatttt caattaaatc tcctaaaaga gcaccagtct
    11101 ccgcatctcg gacagtggtt ccttgtggta ctttaacata ggtatcttct gaaccacgac
    11161 cgtgcatccc tttactcatc ccattttcac ctggctgcgc tttgaaatgg cgattgaacc
    11221 gaaaatccat caatgtacgt aacccttcat cgacgatcaa gatgacatcg ccgccacgac
    11281 caccgtctcc gccagccggt ccgccgtcag gaacgtattt ttcgcgacga aatgcaacca
    11341 ttccgtctcc gcccttgcca gctttcacat cgatcgttac ttgatctaaa aacatggaca
    11401 taattaagtc ctcctattat tcatttattt atttgactgc ctgaatttcc acaataaaca
    11461 aaagtcttac ttattttatc ggtgaaatct gattttgtct atcatttcag caaaaagatt
    11521 gtttaccttc ttcttttttt atcatttggt aaggtttcca accttttttc tgctaccaag
    11581 tataattttt tgacaaaata ttctttgcgt agcagaataa cagtgtatta attgtattaa
    11641 ttgaggatgc cgtttcacag cacccctaat aaaggaggaa cttttgatat gacagtaaaa
    11701 gtaggtatta acggatttgg gcgtattggc cgtctggctt tccgccgcat caaagaagtc
    11761 tcagatgata ttgaagtagt agcaatcaac gacttaacaa gtccaactat gttagcacaa
    11821 ttattgcaat ttgactctac tcatggtact tatcctggca cagttactgc aacagaagac
    11881 tcaatcgtag tggatggcga agcaactcgt gtttatgcag aacccgacgc aagcaaaatc
    11941 ccttgggcaa aagaaaacgg tgtagatatc gtactagaat gtactggttt ttatacatct
    12001 gaagaaaaag caaaagcgca tttagatgct ggtgtcaaac gagtagttat ttctgcccca
    12061 gctggtgcta tgaaaaccat cgtctataac gtcaatgatg atacattaga tgaaaacgac
    12121 aaaatcatct cagcaggttc atgtacaaca aactgtttag cacctatggc ttatttctta
    12181 aataatgaat ttgggatcga agttggtaca atgacaacag ttcatgccta cacttccaca
    12241 caaatgctct tagatggacc tgtaaaaggc ggtaatttgc gtgctgctcg ttcagctgct
    12301 gacaatacta tcccacattc tactggtgct gcgaaagcaa tcggcttagt tatccctgag
    12361 ctacaaggaa aattacaagg acacgcacaa cgtgttccag tcgttgatgg ttcattaact
    12421 gaattggttt cagtattgaa aacaaaagta actgctgatc aagtaaacga agcaatcaaa
    12481 aaacacacag ttgacaatcc ttcattcggg tatgatgacc gtcaaatcgt ttctagcgat
    12541 gtcattggaa caactcaagg ttcgatcttt gacccaacgc aaacagaagt aacaactgct
    12601 ggtgatttcc aacttgttaa aactgttgca tggtatgaca atgagtatgg atttacttgc
    12661 caaatgattc gcttactaga aaaattcgct aacttgtaat ttgatagatc aatcgataaa
    12721 agaagccttt gactggatcc agtcaaaggc ttctttcttt tcatccccta cttttaaact
    12781 cgttcaatga acatattggc ttaaaaattg ttggactact tgctgatatt tttcaggatc
    12841 tgtcttgtat gcttccgcat gctcggctcc ttttacaaca tacttttctt ttggtccctt
    12901 cgttgcacga tagaccttat ctaacatttc aaatggtaca aatgtatctt cgtctccatg
    12961 tataaagagc attgggcgct ggtttttctt caattgttcc actgcatttg cttcaccgaa
    13021 aaagtagcca gcacggactt ttgtcactag actcgttact tgcataagcg gaaatgctgg
    13081 aagactaaac atatcgtcta gctgataagc aagctcatca tgaacggaag aataaccgca
    13141 atcttcaatg attgctttca cattatctgg tagtttttct ccgctagtca tcataactgt
    13201 tgctgctccc atgctgacac cgtatagaac gatttcttgc gattttccat tgttttctag
    13261 cactttgttt atccactgta catagtcttt acgctctggc catccaaatc caatgtaatc
    13321 cccttcgctt tttccatgtc ctcttgcatc aggaacaagg acattgtaac ccatatcatg
    13381 aaacatcttt gcgtaattgg tcatcgtttc agcgtttccc atatagccat gagccacaag
    13441 agctgttttt tcacttttcg tttcagcagg aagataaatc gctgataatt tcagaccgtc
    13501 ttttgaagtg atggtccaat cgcttcggtt ttcttttgaa ctaaaccatt tatgtgcatc
    13561 cgtttctttg gatgtctgtg ttgtaccagg tgtatcttcg tctaaaaagt ctttctcaga
    13621 aggcacaaca gcataattat aaaaataatt ccctgcaaac actaacgcaa caatcagagc
    13681 taaagcgacg cctaaaagga ttttcatcca aagtttcata aatcatccat ctcatttctc
    13741 ttttttcata taaccttgaa ttagtataat caaagaatct ctactatgca atgttcattt
    13801 ttataacccg cgaattgtaa aattaagtta gaaaaataaa aaggcattta tggtacactc
    13861 aaattgtatt tccgacgaaa gaaaacaaag gagtgtaacc ataaatgacc tacaaacatc
    13921 ttaccataga cgaactgaca atgatagaat catattatct tcaacataat aagccggttg
    13981 aaatcgctaa ccgaatggga cgtgctatac aaactattta taatgtagtc aataagttca
    14041 agcaaggcaa gactactctt gattattggc accagtataa agaaaataag aaaaaatgtg
    14101 g
//
LOCUS       DAZKKZ010000068        13703 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.070, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000068 DAZKKZ010000000
VERSION     DAZKKZ010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13703)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13703)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13703
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.070"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..902)
                     /locus_tag="ACG8LA_002320"
     CDS             complement(<1..902)
                     /locus_tag="ACG8LA_002320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside hydrolase"
                     /protein_id="HFQ0204599.1"
                     /translation="MRKVIIDCDPGIDDTLALSLAVKSPDIEVVAITVVCGNVPADIG
                     TQNVLKCLERCDRLDIPVYQGMEKPLKQPFISAQDTHGMDGLGETNFPMILRKQAEPL
                     HAVDFLADYFKEKTNTSVIALGPLTNIAFALKVNPNIGKHMDRFVSMGGTYKSHGNCS
                     PVAEYNYWCDPEAASYVFENLKQTIEMVGLDVTREIVLTPTILEYCCQMNPEEGEYLK
                     AITRFYFDFHWKQERILGCVINDPLAVAYFIEGAICEGFKSFTAVETQGISRGQTLVD
                     RYEFWQKPANSKIMTKVDTRLFSE"
     regulatory      complement(926..970)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            1185..2153
                     /locus_tag="ACG8LA_002321"
     CDS             1185..2153
                     /locus_tag="ACG8LA_002321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFQ0204600.1"
                     /translation="MVIFYFILILIIIGISYHFLSYFYAKKLVRAGVQRGYDWYEDTG
                     HRLMDPAAVTSVEKKRQKLEEECESFWEQGTPKTIKSYDGLKLAGQMFIHPNKQNKWV
                     ICVHDYRSTGKRDMSHIGKRYAEKGFNVLVPDLRAHGESEGEIIGMGWLDRLDLIAWI
                     QLILDEQPNASIILHGGSMGASTIMMASGEKLPSAVKGFILDSGYVSVYAEFRYMLSK
                     ITVFPKKMVMRYANHYAQKYAGYSLKQASATRQLGSNHLPLLVIHGERDHFVPTEAAY
                     TIQNATAGDKALLLVPEAEHLEASMKDPKTYWTVIFSFIEQRITMD"
     gene            2266..2544
                     /locus_tag="ACG8LA_002322"
     CDS             2266..2544
                     /locus_tag="ACG8LA_002322"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFQ0204601.1"
                     /translation="MEIKEEKNRLALFNDEQQEIGEMTWSDAGPDIMIIDHTFVDPAY
                     RGQKLAEKLVYTGVELARRDGKKIIPLCPYAKKEFEKKPEYQDVLRQS"
     gene            2662..2898
                     /gene="secG"
                     /locus_tag="ACG8LA_002323"
     CDS             2662..2898
                     /gene="secG"
                     /locus_tag="ACG8LA_002323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015136 - sialic acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015739 - sialic acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HFQ0204602.1"
                     /translation="MYNLILGIVIVLSIVMVIAIMMQPSKQNSAASAFTGGADQLFGK
                     QKARGFEAVMQRSTAVMGAIWMILLFVLAYLSSK"
     gene            3001..3756
                     /locus_tag="ACG8LA_002324"
     CDS             3001..3756
                     /locus_tag="ACG8LA_002324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HFQ0204603.1"
                     /translation="MRRVRQLPKPLYAKHGKRAVLLLHAYSGSPNDVRMLARFLEKAD
                     YTVYAPLFKGHGTMEPYDILQEKAESWWADTKKAIHFLQSEQFSDIAVLGLSMGGIFA
                     VRALEEESVIGGGFFCSPLSPVKTNVPENFEKYVRQVLKTAGKSEKEINEKAVAYRSL
                     AEQQLMDIQDQAAIVESRLSDIQQPIFLAQAGKDEMIDPNGVFETARKLSRQRVTLQW
                     YPESGHVITVGTARRELEKDVLEFLEKLPWNEE"
     gene            3759..6116
                     /gene="rnr"
                     /locus_tag="ACG8LA_002325"
     CDS             3759..6116
                     /gene="rnr"
                     /locus_tag="ACG8LA_002325"
                     /EC_number="3.1.13.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HFQ0204604.1"
                     /translation="MTKETIKEKILFFMESSRKRSFSMEEIAEGLGFQKSDDFKLLVQ
                     TIAQMEREQSIVFNKKGKVKLPLKPILIEGTFRANERGFGFVTIDPEEDDIYIPKEAT
                     GFAMDGDTVAIDIMKRANTDMDRGAEGKVVEIRDRATTQLAGEFVAYSEEEIQETDLY
                     GVVIPKDRKLNQFKVYAAAEGVRPVDGSIVLIELTHYPEKGYATSLEGIIKQVIGHKN
                     DPGMDILSIVVANGIPTKFPDDVLSEADEVPDQISEKDITGRRDLRNQLIVTIDGEDA
                     KDLDDAVTVKKLDNGNYFLGVHIADVSYYVTQGSQLDREAYERGTSVYLTDRVIPMIP
                     QRLSNGICSLNPHVPRLTMSCEMEIDPNGQVVSHDIFPSVIQTTERMTYTAVNQILED
                     QDEETMQRYAQLVPMFQEMGELHRILETMRIKRGAISFEDREAKILVDAEGHPNDIQL
                     RSRGIGERLIESFMLAANETVAEHYNKLNLPFIYRIHEQPKEEKMQRFFDFASALGIL
                     VRGTKGTITPKDLQHVIEGVEDKPEAAVINTMLLRSMQQARYSEDNFGHYGLAADYYT
                     HFTSPIRRYPDLIVHRLIRSYSEDKSESNQSSWAAELPEIADHSSKMERRAVETEREV
                     DSMKKAEFMMDKVGEEFDGIISSVVKFGLFIELPNTVEGLIHINELKQDYFHFVENHL
                     ALVGERTGLTFKIGQKVRVKVVKADPDERAVDFELVSAEEVTALERPKARNGKFGKRE
                     GKQAGKRSEKNGKKNKRYSDSKQTFGKKKGKKPFYKDVKKKKKKK"
     gene            6138..6602
                     /gene="smpB"
                     /locus_tag="ACG8LA_002326"
     CDS             6138..6602
                     /gene="smpB"
                     /locus_tag="ACG8LA_002326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HFQ0204605.1"
                     /translation="MPKGEGKLIAQNKKARHDYSIIDTMEAGMVLQGTEIKSIRNSRI
                     NLKDGFIRVRNGEAFLHNVHISPYEQGNIFNHDPLRTRKLLLHKKQIVRLENELKNTG
                     ITVVPLKVYIRNGYAKVLIGLAKGKKSYDKREDLKRKDIDRQIDRTLKNFSR"
     gene            6904..7623
                     /gene="atpB"
                     /locus_tag="ACG8LA_002327"
     CDS             6904..7623
                     /gene="atpB"
                     /locus_tag="ACG8LA_002327"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HFQ0204606.1"
                     /translation="MDERSLTFHIGPIWFDGTVCIMVLLTCLIVFFLAYFFTRNLKLK
                     PTGKQNAIEWVIDFSRGIVTDNLPRKELSNFHLLAFTLFLFVFVANNIGLVTKIVLPN
                     ETTLWKSPTADPFVTLTLAFIMILLTHLFGVKKLGFKGYFVNSFLKPYSFMFPMKLIE
                     EFTNLLTLALRLYGNIYAGEVLLTLIAKMMTSLGWFSLPLAIPLEMVWIAFSLFIGSI
                     QAFVFVTLSMVYMSHKIEVEE"
     gene            7676..7891
                     /gene="atpE"
                     /locus_tag="ACG8LA_002328"
     CDS             7676..7891
                     /gene="atpE"
                     /locus_tag="ACG8LA_002328"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045263 - proton-transporting ATP
                     synthase complex, coupling factor F(o) [Evidence IEA];
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F0 subunit C"
                     /protein_id="HFQ0204607.1"
                     /translation="MNYIAAAIAIMGAAIGAGYGNGQVISKTIESMARQPEMSGQFRT
                     TMFIGVALVEAVPILGVVIALILVFAV"
     gene            7982..8506
                     /gene="atpF"
                     /locus_tag="ACG8LA_002329"
     CDS             7982..8506
                     /gene="atpF"
                     /locus_tag="ACG8LA_002329"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045263 - proton-transporting ATP
                     synthase complex, coupling factor F(o) [Evidence IEA];
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HFQ0204608.1"
                     /translation="MLNQLAIAEVGNAMLGNIIVVSGSFLILLALLKHFAWGPISDIL
                     KKREDKIANDLDSAEQSRINSAKMEQEREQQLLASRSDAADIIKNAKESGELSRQNIL
                     KDAQEEAARLKSKAQADITVERDSALNSVKDDVAELSLQIAEKILNKELSPEMHESLI
                     NQYIEGLGSSNETR"
     gene            8493..9035
                     /locus_tag="ACG8LA_002330"
     CDS             8493..9035
                     /locus_tag="ACG8LA_002330"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HFQ0204609.1"
                     /translation="MKLDKYTVGRRYGKALFELAIDSNQAEEIYQDLVSLRQIYEQVP
                     GLGNMLSDVRLEPHEKREIMDKLVSGYDGIVKNFLEVVYEYNRMDDLLFMIEEYERRY
                     DEHQGLLLGSVTTAVPLSDEQRIQLEKNVAKTMDYQSVELKQIVDSSIIGGAIVEANH
                     RVIDGSIRTQLEKMRNQLNR"
     gene            9058..10614
                     /gene="atpA"
                     /locus_tag="ACG8LA_002331"
     CDS             9058..10614
                     /gene="atpA"
                     /locus_tag="ACG8LA_002331"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_component: GO:0045262 - plasma membrane
                     proton-transporting ATP synthase complex, catalytic core
                     F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HFQ0204610.1"
                     /translation="MAIKAEEISALIKEQIENYQNVLSVEEIGTVTYVGDGIARAHGL
                     ENAMSGELLEFSNGSYGMAQNLESNDVGIIILGDFESIREGDKVKRTGKIMEVPVGEA
                     LIGRVVNPLGQPIDGLGEIVTDKARPVEAMAPGVMQRKSVNEPMQTGLKAIDALVPIG
                     RGQRELVIGDRKTGKTSIAIDTIINQKGQDMICIYVAIGQKDSTVRTQVETLKKYGAM
                     DYTIVVNAGASQPAPLLYIAPYAGTAMGEEFMYNGKHVLIIFDDLSKQAVAYRELSLL
                     LRRPPGREAYPGDVFYLHSRLLERAAKLSDDLGGGSMTALPFVETQAGDISAYIPTNV
                     ISITDGQIFLESDLFYAGTRPAVDAGLSVSRVGGSAQIKAMKKVAGTLRLDLASYREL
                     EAFTQFGSDLDAATQAKLNRGRRTVEILKQKLHAPLAVEKQVVILYALTHGFLDSIPV
                     DSILDFEHELFEYLDTNHSDIFETIRTTKDLPEEEALNSAIQEYKDMFLATKGNNSST
                     EDKLKSIQNA"
     gene            10628..11530
                     /locus_tag="ACG8LA_002332"
     CDS             10628..11530
                     /locus_tag="ACG8LA_002332"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HFQ0204611.1"
                     /translation="MGASLNEIKTRIASTKKTSQITRAMQMVSASKLTKSEASSQKFQ
                     VYATKVREIVTHLTATQLNDIASENPRGDINYNSMLLSRPVKKTGYIVITADGGLVGG
                     YNSSILKQTMSILEEDHQSPDDYVMIAIGGTGADFFKARGINLAYELRNLSDQPSFDE
                     VRKIVNMATTMYQNEVFDELYVCYNHHINSLTSQFRVEKMLPISDLDPEEATTFEQEY
                     IFEPSKEEILSQLLPQYAESLIYGAIVDAKTAEHAAGMTAMKTATDNAANIIDELTVS
                     YNRARQGAITQEITEIVAGASALE"
     gene            11553..12959
                     /gene="atpD"
                     /locus_tag="ACG8LA_002333"
     CDS             11553..12959
                     /gene="atpD"
                     /locus_tag="ACG8LA_002333"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_component: GO:0045262 - plasma membrane
                     proton-transporting ATP synthase complex, catalytic core
                     F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HFQ0204612.1"
                     /translation="MSSGKIVQVIGPVVDVEFSLDQSLPDINNALVVYKNDENKSKVV
                     LEAALELGDGVIRTIAMESTDGLQRGMEVIDTGKAISVPVGKETLGRVFNVLGDTIDL
                     ETPFPEDAERSEIHKKAPAFDELSTSTEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYYEMKDSGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSITSIQAIYVPADDYTDPAPATAFAHLDATTNLERKLTE
                     QGIYPAVDPLASSSSALAPEIVGEEHYKVATEVQHVLQRYRELQDIIAILGMDELSDQ
                     EKVLVSRARRVQFFLSQNFNVAEQFTGLPGSYVPVEETVKGFREILEGKYDDLPEEAF
                     RSVGRIEDVVEKAKTLGY"
     gene            12973..13395
                     /locus_tag="ACG8LA_002334"
     CDS             12973..13395
                     /locus_tag="ACG8LA_002334"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HFQ0204613.1"
                     /translation="MDQYLTVNVVTPAGLVYDHHAAIVVARTTAGELGILPKHAPIIV
                     PLTIDEVRVKRTDSDTHVDWIAVNGGIMEVRDNVVSIVADSAERERDIDVSRAERAKQ
                     RAERQIEEAKAKQDTNELKRATVALHRAINRIKVSKHS"
BASE COUNT         4530 a         2452 c         2988 g         3733 t
ORIGIN      
        1 ctttcggaaa aaagacgagt atctactttt gtcataattt tactgttagc aggtttctgc
       61 caaaattcat aacgatcaac caatgtttgt ccacgactta ttccctgagt ttccacagcg
      121 gtgaagcttt tgaaaccttc acagatggcc ccctcgatga aataagcaac agctaacgga
      181 tcattgatga cacatcctaa aattctttct tgtttccagt ggaagtcaaa ataaaaacga
      241 gtgatcgctt ttaaatactc tccctcttca ggattcattt gacagcagta ttcgaggata
      301 gtcggtgtca agacgatttc tcttgtcaca tctaacccaa ccatttctat cgtttgtttg
      361 agattctcga atacataaga agctgcttca ggatcacacc agtaattgta ttcagcaact
      421 ggcgaacagt taccatggct tttgtaagtt ccacccatcg agacaaaacg atccatatgt
      481 ttcccaatat ttgggttgac tttcaaagca aaagcgatat tggtcaaagg acccaaagca
      541 atgactgatg tatttgtctt ttctttgaaa taatcagcca aaaaatcaac ggcatggaga
      601 ggttctgcct gttttctcaa gatcatcggg aaatttgttt cccctaaacc atccatacca
      661 tgagtgtctt gtgcactgat gaaaggttgc ttcaaaggtt tttccattcc ttgataaaca
      721 ggaatgtcta aacgatcaca gcgttccagg catttcagca cattctgcgt acctatatct
      781 gcagggacat tcccacaaac tacggtaata gcaactactt cgatatcagg ggatttgaca
      841 gctaatgata aagctaaagt gtcgtcgatc cctggatcgc aatcaataat tacttttcgc
      901 attatttcca atctcctttc tttagagata cttagttttt tattctggga agtttccgaa
      961 ccagtccaag acgagcgtct tgattataat gcacgaaatt agtatactgg cttttattgc
     1021 gaatgtaaat gctctcttac aagtaaatct attgaggaga actttaagta aatgatacaa
     1081 tgaaaaagaa atggaattta cgtgtgccga aaataaagaa tcctatggat cggtacattg
     1141 gataatagat agattatagt ttggcagaaa gcggcgggtg tacaatggtt attttttatt
     1201 tcattcttat tctgataatt atagggatca gttaccattt tctttcttat ttttatgcaa
     1261 agaaattagt aagagcggga gtacagagag gatatgactg gtatgaagac actggtcatc
     1321 gtttgatgga ccctgctgca gtcacgtcag tagaaaaaaa acgacaaaaa ttagaagaag
     1381 agtgtgaaag cttttgggag cagggaacac ccaaaacaat caaaagttat gacgggttga
     1441 aactagctgg tcagatgttc atccatccaa ataagcagaa taaatgggtc atttgcgtac
     1501 atgattaccg aagcacaggg aaaagagaca tgtctcatat aggtaaaaga tatgcagaga
     1561 aaggattcaa cgttcttgta cctgatttac gtgcgcacgg agaaagtgaa ggagaaatca
     1621 tcggaatggg atggctagat cggctagatt taattgcctg gatccaactc atcttagatg
     1681 aacagccgaa tgcgtccatt attttacacg gcggatcaat gggagcttct acgatcatga
     1741 tggcaagtgg tgaaaaactt ccatcagcgg tcaaaggatt tattttagac agcggatatg
     1801 tttctgttta tgcagaattc cgatatatgt taagtaaaat cactgtcttt cctaaaaaaa
     1861 tggtcatgag atatgcgaat cattatgccc agaaatacgc cggttactcc ttaaagcaag
     1921 catcagctac gagacagctt ggcagcaacc atctgccttt attagtcatc catggtgaaa
     1981 gagatcattt tgtccctaca gaagcagcgt acacgattca aaatgctacg gcaggggata
     2041 aagcactgct gcttgttcca gaagcagaac acttggaagc atcgatgaaa gatccgaaaa
     2101 cctattggac agtgattttt tcatttattg aacaaagaat aacgatggat taattttctc
     2161 ttcttttttg taagtaattc gaggataaat aattgtttat agatctggag actgctaaaa
     2221 taaggtagga ataaaaaaat atcagttatt tgaggagtgc ggcatatgga aatcaaagaa
     2281 gaaaaaaatc gtcttgcttt attcaatgat gagcaacaag agattggaga aatgacatgg
     2341 tcagatgcgg gcccagacat catgatcatt gaccatacat ttgtagatcc agcatatcgt
     2401 ggtcaaaagt tagctgaaaa gctagtgtat actggagtag aattagcaag acgagacggg
     2461 aaaaagatca ttcctttatg cccttatgca aaaaaagagt ttgaaaagaa accagaatat
     2521 caagacgtct tacgtcagtc ataagaataa cagctgaaag ttttgaactt tcagctgtta
     2581 ttccatttat atagagttgt cacggacttt tatctatgat aaagttaaag agacgatatc
     2641 ttttgggaag gaggctgcga tatgtataat ttaattttgg gaatcgtgat cgttttatcg
     2701 attgttatgg tcattgcgat tatgatgcag ccaagcaagc aaaatagtgc agcgagtgca
     2761 tttaccggcg gtgcggatca actattcggc aaacaaaaag ctcgcggctt tgaagctgtc
     2821 atgcagcgat caactgcagt tatgggagct atctggatga tcttattatt tgtcctagca
     2881 tatttatctt cgaagtagtt gaataagcct ctcgcaaaac ggcgggcggc tttttttatt
     2941 gcaaagagaa cgcttaagaa gaagttatga aagaaactat ggtaaaatga ggcgaaagag
     3001 gtgagacgag tgagacaatt accaaaaccc ctttatgcaa aacatggaaa gcgagcggtt
     3061 ttgctgcttc acgcttactc aggaagtcca aacgatgttc gaatgctcgc acgatttttg
     3121 gaaaaagcag attatacagt ttatgcgccg ctttttaaag gacacggaac aatggagcca
     3181 tatgatatct tgcaagaaaa agcagaaagc tggtgggcag acactaaaaa agccatccat
     3241 tttttacagt ctgagcagtt ttctgatatt gccgtattag gattatcaat gggcggcatc
     3301 tttgctgtac gagcactaga agaagaatca gtgattggcg gcggtttttt ctgttcgcct
     3361 ttgtctcctg taaaaacaaa cgtgcctgaa aactttgaaa aatacgtacg tcaagtgctg
     3421 aagacagcag gtaaatcaga gaaagaaatc aatgaaaaag cagttgctta ccgctcgtta
     3481 gctgaacaac aattaatgga tatacaagat caggcagcaa tcgtagaaag taggttgtca
     3541 gatatccaac agccgatatt tttagctcaa gctgggaaag atgaaatgat cgaccctaat
     3601 ggcgtatttg aaactgcacg caagttgagc cgtcagcgag tgacacttca atggtatcct
     3661 gaaagtggtc atgtgattac agttggtaca gcaagacgcg aattagaaaa agacgtcttg
     3721 gaatttttag aaaaattacc ttggaatgag gaataaatat gacaaaagaa acgataaaag
     3781 agaaaattct ctttttcatg gaaagcagtc gcaaacgcag tttttctatg gaagaaatcg
     3841 ctgaaggttt agggttccaa aaaagcgatg attttaaatt actagtacaa acgattgctc
     3901 aaatggaaag agaacagagt atagttttca ataaaaaagg aaaagtgaaa cttcctttaa
     3961 aaccaatctt gatcgaagga acatttcgag caaatgaacg aggatttgga tttgtaacga
     4021 ttgatcccga agaagatgac atctatatcc caaaagaagc gactggtttt gcaatggatg
     4081 gagacaccgt agcaatcgat atcatgaagc gagcaaatac agatatggat cgcggagcag
     4141 aggggaaagt agtcgagatt cgagaccggg cgactactca gttagcaggg gaattcgttg
     4201 cttattcaga agaagaaata caagaaacag atctttacgg cgttgttatc ccgaaagata
     4261 gaaagctcaa ccaatttaaa gtatatgcag cagcagaggg agttcgtcca gttgacggaa
     4321 gtattgtgct gatcgaactg acccattacc ctgaaaaagg gtatgcgact agtttagaag
     4381 ggataatcaa gcaagtgatt ggtcataaga atgaccctgg catggatatc ctctcaattg
     4441 tcgtggctaa tggtatccct acgaaatttc ctgatgatgt attgtctgaa gcagatgaag
     4501 ttccagatca aatcagcgaa aaggatataa ctggacgtag agatttaaga aatcagctca
     4561 ttgttacgat tgatggagaa gatgcaaaag atctagatga tgcagttacg gttaaaaaat
     4621 tagataacgg taattatttt cttggagtac acattgcaga tgtttcttac tatgtgacac
     4681 aaggcagtca attggacaga gaagcatatg aaagagggac aagtgtatat ttgactgatc
     4741 gagtgattcc gatgatcccg caacgtttat cgaatggtat ctgttcactg aatccccatg
     4801 ttccaaggct gaccatgagt tgcgaaatgg agattgatcc aaatggacaa gtagtctctc
     4861 atgatatttt cccaagtgtg atccaaacaa cagaacggat gacctacaca gctgtcaatc
     4921 aaatcttaga agatcaagac gaagaaacga tgcaacgcta tgctcagctc gtacctatgt
     4981 tccaagaaat gggtgaattg catcgaatcc ttgaaacgat gcgaatcaaa cgtggcgcga
     5041 tttcttttga ggatcgcgaa gcgaaaatcc ttgttgatgc tgaaggacac ccaaatgaca
     5101 tccagctaag aagcagagga attggtgaac gcttgatcga atctttcatg cttgcggcca
     5161 atgaaacggt agctgaacat tataataaat taaatctgcc gtttatttac cgaatccatg
     5221 aacagccaaa agaagaaaaa atgcagcgct tctttgattt tgcttcagct ttgggcattc
     5281 tggtccgagg aacgaaagga acgatcacac caaaagattt acagcatgtg atcgaaggag
     5341 tagaagacaa accagaagct gcagttatca atactatgtt gctaagaagc atgcaacaag
     5401 cacgctattc agaagacaat tttgggcatt atggcttagc ggcagattac tacacacact
     5461 ttacatctcc tattcgacgc tatcccgatc taatcgtcca tcgtctgatc cgttcttaca
     5521 gtgaagataa aagtgaaagc aatcaaagtt cgtgggctgc ggaacttcct gaaattgcag
     5581 atcatagttc taagatggaa cgtcgtgcag tagaaacaga acgtgaagta gattccatga
     5641 agaaagcaga attcatgatg gacaaagtgg gagaagaatt cgatgggatc atcagctctg
     5701 ttgtgaaatt cggcctgttt atcgaactgc cgaatacagt agaaggattg atccatatca
     5761 atgaattgaa acaggactac ttccattttg ttgaaaatca tttagctctt gtaggtgaaa
     5821 gaactggtct gacttttaaa atcggacaaa aagtgcgcgt aaaagtagtc aaagctgatc
     5881 cagatgaacg agcagtggat tttgaactcg tttccgcaga agaggtcact gcgttggaac
     5941 gtccaaaagc acgcaatgga aaatttggaa aacgagaagg aaaacaagca ggcaaacgct
     6001 cagaaaaaaa tggcaagaag aacaaacgat atagtgatag taagcaaacg ttcggtaaga
     6061 aaaaagggaa aaagccattt tacaaagatg tcaaaaagaa gaaaaagaaa aaataaaatg
     6121 agttggagga aacagctatg ccaaaaggcg agggaaaact aattgcacaa aacaagaaag
     6181 ctcgccatga ttattcgatc atcgacacga tggaagcagg gatggtcttg caaggaacgg
     6241 agatcaagtc gatacgaaac agccggatca atctgaaaga tggatttatt cgcgtccgca
     6301 acggggaagc tttcttgcat aatgttcata tcagtcctta tgaacaagga aatattttta
     6361 atcatgatcc gttgcgcacg agaaagttat tattacacaa gaaacaaatc gttcgtcttg
     6421 aaaacgaatt gaaaaacact ggaatcactg ttgttccttt aaaagtctat attcgtaacg
     6481 gctatgccaa ggtattgatt ggtctggcaa aagggaaaaa atcgtatgat aaacgggaag
     6541 atttgaaacg aaaagatatc gatcgacaaa ttgatcgaac attaaaaaat ttctctagat
     6601 aatttcatta tcctttttcg catattcggt gcttttgctt ttacttaatg ataaaatttg
     6661 ttagcattta atctgataaa acatgattat cacaggtttt ttcttagatc aggagcaccg
     6721 tgcatgggga aaaattcgct tcgtttttga ctgaaataaa aaagtgtcta attttcatga
     6781 aaatgttttg aattttctgt ttcatggtgg tatgataccg tgtggttaga aaccgattgg
     6841 aaaaaaccag atacgcacat gaattgattt tatgtgaatt tcggggaaaa gaggtgaaat
     6901 ggattggatg aacgctcgct aacgtttcac attggaccaa tttggtttga tggtacagtt
     6961 tgtataatgg tgttactgac ctgtttgatt gttttcttct tagcttactt ttttacaaga
     7021 aatcttaagt tgaaaccaac aggcaaacaa aatgcgatag aatgggtcat tgattttagt
     7081 cgaggaatcg taacagataa tctgcctaga aaagaattga gcaatttcca tttgttggca
     7141 tttacattgt ttttatttgt ttttgttgca aacaacatag gtttagtaac aaaaatcgtc
     7201 ttacctaacg aaacaacact ttggaaaagc ccgacagcag acccgtttgt tactttaact
     7261 ttggcattta taatgatctt acttactcac ttattcgggg tgaaaaagtt aggcttcaaa
     7321 ggatatttcg taaattcgtt cttgaaaccc tatagtttta tgtttccgat gaaactgatt
     7381 gaagaattta caaatttatt aacacttgct ttacgtcttt atgggaatat ttatgcgggg
     7441 gaagttttgc taaccttgat tgcaaaaatg atgacaagct taggctggtt ctcattacca
     7501 ttagcaattc cattagagat ggtctggatc gcgttctcct tgtttattgg gagcatccaa
     7561 gcatttgtct ttgtcacttt gtcaatggtt tatatgagcc ataagattga agtagaagaa
     7621 taatactcgg ttaaaaaaca aactactatt tatctatttt aggaggaaaa caattatgaa
     7681 ttatatcgca gcagcaatcg caatcatggg agcagcaatc ggagccggtt atggtaacgg
     7741 tcaagttatc tctaaaacaa tcgaatcaat ggctcgccaa cctgaaatgt ctggtcaatt
     7801 ccgtacaaca atgtttatcg gggtagctct agttgaagct gttcctatct taggggtagt
     7861 tatcgccttg attctagttt ttgccgttta attgaatcag tattaaggca gaaacaacat
     7921 cgtttgttac tgctttttta catggaaact agaaatactc caaagaaagg aaggctcgcc
     7981 tatgctgaat caattggcaa ttgcagaagt tggcaatgcg atgttaggta atatcatcgt
     8041 tgtcagcggc tcatttttga tactactggc tctcttgaag cactttgctt ggggaccaat
     8101 cagcgatatt ttgaaaaaac gtgaagacaa gatcgccaat gatttagatt ctgcagaaca
     8161 atctcgcatc aactcagcga aaatggaaca agaacgcgaa caacaattgt tagcctctcg
     8221 ttctgatgca gctgatatca tcaaaaatgc gaaagaaagt ggagaattaa gccgccaaaa
     8281 tattttgaag gatgctcaag aagaagcagc tcgtctaaaa agcaaagccc aagctgatat
     8341 cactgtagaa cgtgattcag cgctgaactc tgtaaaagac gacgttgcag aactctctct
     8401 tcaaatcgcg gaaaaaatct tgaacaaaga attatctcca gaaatgcatg aatcattaat
     8461 caatcaatac attgaaggtc taggttcttc aaatgaaact agataaatat acagtaggaa
     8521 gacgttacgg gaaagcttta tttgaactgg cgatcgattc aaatcaagca gaagaaatct
     8581 atcaagatct cgtaagttta cgtcaaatct atgaacaagt acctggatta gggaatatgt
     8641 taagtgatgt tcgtctagaa cctcatgaaa aacgagaaat catggacaag cttgtcagcg
     8701 gttatgatgg gatcgttaaa aactttttag aagttgttta tgagtataac cgaatggatg
     8761 accttttgtt catgatcgaa gaatatgaac gtcgatatga tgaacatcaa gggttactat
     8821 tgggaagtgt cacaacagca gtcccacttt cagacgaaca acgaatacaa ttagaaaaga
     8881 atgttgcaaa aacaatggac tatcaatcag ttgaattaaa acaaatcgtt gattcttcta
     8941 ttattggtgg cgcgattgtt gaagccaacc atcgagtaat cgacggaagc attcgcacgc
     9001 aattagaaaa aatgcgtaat caattaaaca gatagtacaa agaggtaggt gaatcgaatg
     9061 gccatcaaag cagaagaaat tagtgccttg attaaagaac aaattgaaaa ttatcaaaac
     9121 gtgctttcag tcgaagaaat cggtaccgta acttatgtag gtgacgggat cgctcgtgca
     9181 catggtttag aaaacgcgat gagtggtgag ttgcttgaat tttcaaacgg ctcatacgga
     9241 atggcgcaaa acttagagtc aaatgatgta ggtatcatta tccttggcga tttcgagtcc
     9301 attcgtgaag gagataaagt aaaacgaaca ggtaagatca tggaagttcc agttggagag
     9361 gccttgatcg gtcgggtagt caatccgcta ggtcaaccaa tcgacggact aggtgaaatc
     9421 gttactgaca aagctcgtcc agtagaagcg atggcaccag gtgttatgca acgtaaatct
     9481 gttaacgaac caatgcaaac agggctaaaa gcgatcgacg cccttgtgcc aatcggacgc
     9541 ggacaacgtg aattagtcat cggtgaccgt aaaacaggga aaacttctat tgcgatcgat
     9601 acgatcatca accaaaaagg tcaagatatg atctgtatct atgtagcaat cggacaaaaa
     9661 gattctacag ttcgtacaca agttgaaaca ttgaaaaaat atggcgcaat ggattacaca
     9721 atcgttgtga atgccggtgc gtctcaacca gcaccattgc tttatatcgc accatatgct
     9781 ggtactgcaa tgggtgaaga attcatgtac aacggtaaac atgtattgat catttttgat
     9841 gatctttcaa aacaagctgt tgcttatcgt gaactttcct tgctgcttcg ccgtccacca
     9901 ggtcgtgaag cttatccagg ggatgttttc tacttacact cacgcttatt ggaacgtgca
     9961 gcaaaattaa gtgatgattt aggtggcggt tcaatgactg ccttaccatt tgttgaaaca
    10021 caagctggag atatctctgc ttatatccca acaaacgtta tttcgatcac tgatggacaa
    10081 atcttcttag aaagcgactt gttctacgca ggtactcgtc cagcggttga tgccggacta
    10141 tctgtatctc gtgtaggggg ttctgcgcaa atcaaagcaa tgaaaaaagt tgctgggact
    10201 ttacgtctag acttagcaag ttaccgtgaa ttagaagcat ttacacaatt cggttctgac
    10261 ttggatgcag caacacaagc aaaactaaat cgtggacgcc gtacagtaga aatcttgaaa
    10321 caaaaattgc atgcaccgct agctgttgaa aaacaagtag tgattttgta tgctttgaca
    10381 catggattct tagatagtat ccctgtagac agtattttag acttcgaaca tgaattattc
    10441 gaatatctgg ataccaatca ttcagatatc tttgaaacaa tccgtacaac aaaagatctt
    10501 ccagaagaag aagcgttgaa cagtgcgatt caggaatata aagacatgtt cttagctaca
    10561 aaaggaaata attcctctac agaagataaa ttgaaatcca ttcaaaatgc atagtgaggt
    10621 gagatgaatg ggtgcttcat taaatgaaat caagacacgt atcgcttcaa cgaaaaaaac
    10681 gagccaaatc acgcgggcaa tgcagatggt gtctgcttct aagttgacaa aatctgaagc
    10741 ttcttcacag aagtttcagg tttatgcaac aaaagtaaga gaaatcgtta cgcatttgac
    10801 tgctactcag ttaaatgata ttgcctcaga aaatcctaga ggggatatca attacaacag
    10861 catgttgctc agccgtcctg ttaagaaaac gggttatatc gtcatcactg cagatggcgg
    10921 tttagtcggt ggatataaca gctcgatatt gaaacaaacg atgtctattt tagaagaaga
    10981 ccaccaatca cccgatgatt acgtgatgat cgcaattggc ggaactggtg cagacttctt
    11041 taaagcacgc ggtatcaatc tagcatatga gctgcgcaat ctatctgatc agccaagctt
    11101 tgatgaagtc cgcaaaatcg taaatatggc aacaactatg taccaaaacg aagtattcga
    11161 tgaattatac gtatgttata accatcatat caattcgcta actagtcagt ttcgtgtaga
    11221 aaaaatgctg ccaatctcag acttagatcc agaagaagca actactttcg aacaagaata
    11281 tatttttgaa ccttcaaaag aagaaatctt gtctcagtta ttgcctcagt atgctgaaag
    11341 tttgatctac ggtgcgatcg ttgacgccaa aacagcagaa catgctgctg gtatgacagc
    11401 aatgaaaaca gcaactgata atgctgctaa tatcattgat gagctgacgg tttcttacaa
    11461 ccgtgcaaga caaggggcta ttacccaaga aattaccgaa attgttgccg gagcttcggc
    11521 actagaatag tattgagatt ggaggaaaaa agatgagttc aggcaagatt gttcaagtaa
    11581 tcggtcccgt tgtcgacgtg gaattttctt tagaccaatc cttaccagat atcaacaacg
    11641 cattagttgt ttataaaaat gacgaaaata aatcaaaagt tgttcttgaa gcagcgttag
    11701 aattagggga cggagtgatc cggaccattg cgatggaatc aacagatggt ttacaaagag
    11761 gaatggaagt cattgataca ggcaaagcaa tctctgttcc tgtaggtaaa gaaacattag
    11821 gtcgcgtatt caacgtacta ggagatacga tcgatttaga aacacctttc ccagaagatg
    11881 cggaaagaag cgaaattcat aaaaaagcac cagcctttga cgaattaagt acaagtacag
    11941 aaattttgga aacagggatc aaagttatcg atttgcttgc cccatattta aaaggtggga
    12001 aagtcggact attcggtggt gccggtgttg gtaaaaccgt actgatccaa gaactgatcc
    12061 ataatatcgc ccaagaacat ggtggtattt ctgtatttac cggtgtaggt gaacgtactc
    12121 gtgaaggtaa tgacttgtat tatgaaatga aagattcagg agttatcgaa aaaacagcca
    12181 tggtgttcgg acaaatgaac gaaccaccag gtgcacgtat gcgtgttgct ttgactggtt
    12241 tgacgattgc ggaatatttc cgtgatgtag aaggtcaaga tgtactgttg tttatcgaca
    12301 acattttccg tttcactcaa gctggatctg aagtatcagc cttgttagga cggatgcctt
    12361 ctgcggttgg ttatcaacca acattggcaa cagaaatggg tcaattgcaa gaacgtatca
    12421 catctacgaa aaaaggttcg atcacatcga tccaagcaat ctatgtgcca gccgatgact
    12481 acactgaccc ggcgccggca acagcattcg cccatttgga tgcgacaacc aacttggaac
    12541 gtaaattaac agaacaaggg atttatccag cggtagatcc attggcttct tcttcaagtg
    12601 ctttagcacc tgaaatcgtg ggagaagaac attataaagt agcaacagaa gtccaacacg
    12661 tattgcaacg atatcgtgaa ttacaagata tcattgctat cttaggtatg gatgaattat
    12721 ccgatcaaga aaaagtgtta gtttctcgtg cccgcagagt ccaattcttc ttgtcacaaa
    12781 actttaacgt ggctgaacaa tttactggtc ttccaggttc atatgtccct gtagaagaaa
    12841 cagtgaaagg attccgcgaa atcttggaag gcaaatacga tgatcttcct gaagaagctt
    12901 tccgaagtgt tggccgaatc gaagacgtcg tagaaaaagc gaaaacacta ggctactaga
    12961 aaggggtgcc ccatggatca atatttaaca gtaaatgtgg taactcctgc cggtttggtc
    13021 tatgatcacc atgcagctat cgtcgttgca cgtacgacag ctggtgagct tgggattttg
    13081 cctaaacatg caccaatcat cgttccattg acgattgatg aagttcgtgt aaaacgaaca
    13141 gattcagata cccacgtcga ttggatcgct gttaatggcg gaatcatgga agttcgtgat
    13201 aatgttgttt caatcgttgc tgatagtgcg gaacgtgaac gtgatatcga tgtatctcgt
    13261 gcggaacgtg caaaacaacg cgcagaacgc caaatcgaag aagcaaaagc aaaacaagat
    13321 acgaacgaat tgaaacgggc aactgttgcg ttgcaccgag caatcaatcg tatcaaagta
    13381 tctaagcact cataaaatga gatgcggatg tttatccgtg tttaagaaca gtaaaaagag
    13441 gttatgacag aagtggtcag cttcaagaca taagaaggaa tttacgaaaa ttgcttctca
    13501 aatttttgtg aaatctcagc ttatttttcg aagaagctac ttctggaaca ccgtatatcg
    13561 gaggttgtga aatcagcgtt ttgtcctgag tattagagaa acaaatggaa aatagttcct
    13621 catattttgc cgttttttga gctaataccg agggtcagat gattgaacac cgtttatttg
    13681 gaataaggga ctgcgacaag act
//
LOCUS       DAZKKZ010000069        13676 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.071, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000069 DAZKKZ010000000
VERSION     DAZKKZ010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13676)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13676)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13676
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.071"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..2100
                     /gene="acm"
                     /locus_tag="ACG8LA_002335"
     CDS             <1..2100
                     /gene="acm"
                     /locus_tag="ACG8LA_002335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Acm"
                     /protein_id="HFQ0204614.1"
                     /translation="PVHVYADAGRDISSNVTSLTVDPTNITDGGNIKVKFSFDEKKQN
                     IQPGDYLWINWPSEGNIRGEGFQKEIPLMIENKNVGTLTVRKDSAQVVFNENIKNLDS
                     VEGWGQFEIQARNVTDTGEENTGPFTVTSGDKTATVNVTKPASGSSSSVFYYKTGDML
                     PEDTKHIRWFLNINNNGTYVEQPVKISDEIQSGQRLDPSTFEINQIHLGEQKVYRGEE
                     GIQQFLQDFPSATFNFSVTDNYIEITIPKNFVNLRKIMVSYKTIIENPEQINFENHSE
                     AWFKEFNKPAVDGESFNHTVKNISASGGVNGTVRGELKIFKYINDTEIGIPNVTFELR
                     RADEQPIQGQSSILLTSNEQGEASIKGLQVGDYVVKEKEAPNWIDFDPLSSNELKFSI
                     NENDTEGVSLPIYNKKKVTNITATKIWNGGTTPRPSIYFKLFRASTNNWEPVPDAETK
                     RLDNGITSVTWEDIQQYDDSGNEYTFKVQEVDQNGNDYVPSGYQKIENGLVVTNENKE
                     VISVSGQKTWEDNENQDGKRPTTITVNLLADGQPIQHKEVSEKDDWRYRFTNLPKYRD
                     GQEIIYTVTEDNVPEYSTTIDGYNIKNSYTPEKTNISIPGSHITPWKNFPEKTEREKI
                     RNLFSQKLQIFAHTGESSEQRSNYISKRAVPKQITNKSKSILPKTSSKKSSFAVIIGL
                     LIVTICAGIFLQKYKKV"
     gene            complement(2372..2857)
                     /locus_tag="ACG8LA_002336"
     CDS             complement(2372..2857)
                     /locus_tag="ACG8LA_002336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HFQ0204615.1"
                     /translation="MSRATEQEAYELLKKLGISFQKVDHPAITSVKNVPFSLPGPQVK
                     NLLLKSRKGKQIYLVILPDEKHADLKQLAEQLKEKRLSFVSEEQLPDLLGVPAGTVTP
                     LALMHDKEKKIQVVIDAAIDRQDTVGFHPNINTTTLIMDFSDFEKILVYLEHLPVYEN
                     L"
     misc_binding    2947..3292
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            3337..3978
                     /locus_tag="ACG8LA_002337"
     CDS             3337..3978
                     /locus_tag="ACG8LA_002337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HFQ0204616.1"
                     /translation="MEYLIEVMPQLLVGALTTLKLFLFTLIGSLPLGIVLALGLSLHF
                     KPLRYLLQTYVWVMRGTPLLLQLIFIFYGLPTIGIVFDRFEAALIAFILNYAAYFAEI
                     FRGGIQSIPQGQYEAAQVLQLSPFQTVTKIVIPQVTKIVLPSVGNEVINLVKDSSLIY
                     ILGLGDVMRAGKIAMERDATLLPLLGVAIIYLTLTGILTIVMKQVEGKLNYYR"
     gene            3997..4632
                     /locus_tag="ACG8LA_002338"
     CDS             3997..4632
                     /locus_tag="ACG8LA_002338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HFQ0204617.1"
                     /translation="MIELKKVNKAFGEKKIIKDLNLIIPDGKTLAIVGPSGGGKTTLL
                     RILAGLESSDSGEFYLDGVPFNPFELKMKEQVVGVVFQDFQLFPHLNIFENITLAPKM
                     VLKQTKEEYTKKAEELAASLGISDLLNIYPYQLSGGQKQRVAIARALAMNPRVLAYDE
                     PTSALDPELRQQVERLILSLKEDGVTQIIVTHDLVFAENVGDQLLKVSPIH"
     gene            4650..5465
                     /locus_tag="ACG8LA_002339"
     CDS             4650..5465
                     /locus_tag="ACG8LA_002339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HFQ0204618.1"
                     /translation="MKKTSFLFALIAGLLLFAGCSNKKTSADNWATINEEKKIVIGLD
                     DTFVPMGFRDKDGKLTGFDIDLAKAVFEQYGITVDFQPIDWSMKEFELNNGTIDLIWN
                     GYSKTPAREKKVQFTKPYMENDQVLITPKESGITNFGQMNNKRLGAQNGSSGYDVFTK
                     QPEVLKEIVKNQDAVLYDSFNEALIDLKSRRVDGLLMDKVYADYYLKQRNELEDFNIT
                     KGSYESEDFAVGARKSDSTLVKKINEALDQLEKTGEFQKISDKWFGEDVTPRN"
     gene            5784..7220
                     /locus_tag="ACG8LA_002340"
     CDS             5784..7220
                     /locus_tag="ACG8LA_002340"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFQ0204619.1"
                     /translation="MEHKELTSFPKDFLWGSASAAYQVEGAWQEDGKGESVWDRFVRI
                     PGKTFKGTNGDLAVDHYHRYKEDIALMKEQGLKAYRFSVAWTRIFPNGRGEVNQAGLA
                     FYERLIDELIENDIEPMLTLYHWDLPQALQDEYNGWESRQIIEDFTHYAETLFEAFRG
                     KVHYWISLNEQNIFTSLGYLLAAHPPGVTDPKRMYEVNHIANLANASVINKFHELEMP
                     GKIGPSFAYTPNYPIDSNPENVLAAENAEDLMANYWMDVYMWGKYPIAAMRFLEEKGW
                     APTIEAGDAELLESAKPDFLGINYYQTATNAFNPLNGVGAGKMNTTGKKGSSEETGVP
                     GMYKKVENPFVERTNWDWEIDPEGLRIGLRRITSRYRMPVLITENGLGEYDKLTEDKQ
                     IHDDYRINYLQSHVKAIKEAISDGAEVLGYCTWSYTDLLSWLNGYQKRYGFVYVDQDE
                     TQEGSLERYKKDSYYWYQKLIEENGENL"
     gene            7409..9856
                     /locus_tag="ACG8LA_002341"
     CDS             7409..9856
                     /locus_tag="ACG8LA_002341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HFQ0204620.1"
                     /translation="MAQKKRPTKKRKKTKKTKKQKQQQEQMLTIGVGFALILFAVFGF
                     LKLGFLGILIANGFRIIAGNTYQILCLLLAVLGFWIVIKNTEFSIGKNRRWFGGILFY
                     FGILLLLHAHLFGKLHTGEPNIMGTTWDLLASDIKQSQVDNNVGGGMIGAILYHFTYF
                     LIAQPGSYLAAVLLLAGGAFLFSNLEGYQLLNGIQSIGERVQELLEGDPAKQARKQAA
                     KEERMKQRAEAKEARRLAAKEAAEKEAAEYEKKKAVSQQRENTADEWQEPENTEPEQL
                     SFVPIDSFQENIHPANLEKPVPDTPKQTNTAEGFSDELPEDDGTSLEFEIEAEQENQD
                     YELPTVDLLDSIPTVDQSDEYKKIEKNIGVLEQTFQSFGVDAKVVKASLGPSVTKFEV
                     QPAVGVKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNGKISMVSFREIIE
                     AQPNHPDKLLEVPLGRDVSGRVQTADLSKMPHLLVAGSTGSGKSVAINGIITSILMRA
                     KPHEVKLMMIDPKMVELNMYNGIPHLLTPVVTNPRKAAQALQKVVQEMEERYEKFAAT
                     GVRNISGYNEFVQQKNLENGTKHPTLPFIVVIVDELADLMMVASNEVEDAIIRLAQMA
                     RAAGIHMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDSNGAEKLLGRGD
                     MLFLPMGENKPIRVQGAFISDHEVERVVQFVTDQQEAHYEEKMMPTDEVETTGAPEQP
                     QDELFEEAKALVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVVGPSEGSKPRKV
                     FIEQEETSETLPDDNDM"
     gene            10086..11153
                     /gene="rlmN"
                     /locus_tag="ACG8LA_002342"
     CDS             10086..11153
                     /gene="rlmN"
                     /locus_tag="ACG8LA_002342"
                     /EC_number="2.1.1.192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:0016433 - rRNA (adenine) methyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0030488 - tRNA methylation [Evidence IEA];
                     GO_process: GO:0070475 - rRNA base methylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HFQ0204621.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            11143..11349
                     /locus_tag="ACG8LA_002343"
     CDS             11143..11349
                     /locus_tag="ACG8LA_002343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204622.1"
                     /translation="MPNNRILLVFSITIKGAVFLIKELFNLNKRKDSIAKAIKLFLTR
                     KTLIKQRNVLNLMTACLMGVLAII"
     gene            complement(11346..12449)
                     /locus_tag="ACG8LA_002344"
     CDS             complement(11346..12449)
                     /locus_tag="ACG8LA_002344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HFQ0204623.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
     gene            13002..13550
                     /gene="aac(6')"
                     /locus_tag="ACG8LA_002345"
     CDS             13002..13550
                     /gene="aac(6')"
                     /locus_tag="ACG8LA_002345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HFQ0204624.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
BASE COUNT         4673 a         2293 c         2902 g         3808 t
ORIGIN      
        1 cctgttcatg tctatgcgga tgcaggcaga gatatcagca gtaatgtcac ttcgttgacc
       61 gtggacccaa cgaatattac agatggagga aacataaaag taaaattctc gtttgacgaa
      121 aaaaaacaaa atatccaacc aggtgattat ctttggatca attggccaag tgaaggaaat
      181 attcgcggtg aaggattcca aaaagaaatc ccattaatga ttgaaaataa aaatgttgga
      241 actttaacgg tcagaaaaga ttctgcgcag gttgtgttta atgaaaatat taaaaaccta
      301 gactcagtag aaggttgggg gcaatttgag atacaggcca gaaacgtaac cgataccggt
      361 gaagaaaata cgggaccatt caccgtgacg agcggtgata aaacagctac tgtaaatgtg
      421 acaaagccag cttctggttc ttcttctagc gttttttatt ataaaacagg agacatgcta
      481 cctgaagata ctaagcacat tcgatggttt ttgaatatta acaataacgg cacttatgtt
      541 gaacaaccag ttaaaatcag tgatgaaatc caaagtggac aaagattaga tccaagtacg
      601 tttgaaatta atcaaataca cttaggtgaa cagaaggttt atagaggaga agagggaatc
      661 caacaatttt tacaagattt ccccagcgct acatttaatt tttcagtaac tgataattac
      721 attgaaataa ctataccaaa aaactttgtc aatcttagga aaataatggt gagttataag
      781 acgatcatag aaaacccaga acaaataaat tttgagaatc attcggaagc ttggtttaaa
      841 gaatttaata aacctgctgt tgatggagaa agtttcaatc atacagttaa aaatatttca
      901 gcttctggtg gagtcaacgg tacagttaga ggcgaattga agattttcaa atatatcaat
      961 gacacagaga ttggtatccc aaatgtgact ttcgaattaa gacgagcaga tgaacagcct
     1021 attcaaggac agtctagtat cctgttgact tcgaatgaac agggagaagc tagtatcaaa
     1081 ggcctgcaag taggagacta tgttgtaaaa gaaaaagaag cacccaattg gattgatttt
     1141 gatccactaa gttcaaatga actcaaattc tccataaacg aaaatgatac agagggagtc
     1201 agtttaccta tttataacaa gaaaaaggtt acgaacatca cagcaactaa aatttggaac
     1261 ggtggaacca ctccaagacc gagtatttat tttaaattat tcagagcaag tacaaacaat
     1321 tgggaaccag ttcctgatgc agaaacaaaa cgattagaca atggaataac ttcagtgact
     1381 tgggaagata tccaacagta tgatgatagt ggaaacgaat atacgtttaa agtgcaagaa
     1441 gtagatcaaa acggaaatga ttatgtccct tcaggttatc aaaaaattga aaacgggcta
     1501 gtcgttacaa atgagaataa agaagtcatt tcagtctcag gacaaaaaac atgggaagac
     1561 aatgagaacc aagacggcaa acgaccgacg acgatcacag taaatctatt agccgacggt
     1621 caaccgatcc aacacaaaga agtaagtgaa aaagatgatt ggcgctatcg tttcacaaat
     1681 ctgccaaaat acagagacgg gcaagaaatc atctatactg taacggaaga caacgtgccc
     1741 gaatacagta cgacgattga cgggtataac atcaaaaaca gttatacacc ggaaaaaaca
     1801 aatatatcta taccaggtag ccatataaca ccgtggaaaa attttccaga gaagacagag
     1861 agagagaaaa ttagaaatct attctctcaa aaattgcaaa tatttgctca tacaggagaa
     1921 tccagcgaac aaagaagcaa ttatattagt aagagagctg tacctaaaca gataacaaat
     1981 aaatcaaaaa gcattcttcc taaaacaagt agtaaaaaat ctagttttgc tgtaatcatt
     2041 ggtttattga tagtaactat ctgtgctggg atattcttac aaaaatataa aaaagtttag
     2101 ttagaatata atattttttg ttaaatatga ctgaaatcaa aagaataaaa ttccgattta
     2161 taatcgaaaa aagaagcatt tttatatatg cttctttttt cgtagaatca ataaatatgg
     2221 atttggctaa ctatggaaga atactcgtat tagttttcag cgttcatact agttgttaca
     2281 ttgtttgatt ggccaaaaga atttctgata tattttgtgc taaataaaga aaaagacgct
     2341 tgaattggga aataagaaaa ctactctatc attacaaatt ttcataaact ggcagatgtt
     2401 ctaagtaaac aagtatcttt tcaaagtcgg aaaaatccat aatcaacgta gtggtattga
     2461 tatttggatg aaagcctacg gtatcttgac gatcaatagc agcatcgatc acgacttgga
     2521 tttttttctc tttgtcgtgc atcaatgcta atggagtcac tgtacctgct ggaacgccta
     2581 ggaggtcagg aagctgttct tcagaaacaa aagataagcg cttttctttt aattgttcag
     2641 ctagttgttt taaatcggcg tgcttttcat caggcaagat gacaagatag atttgttttc
     2701 cttttcttga tttcaataat agatttttta cttgcggacc aggtagggaa aaagggacat
     2761 ttttgactga cgtaatcgca ggatgatcga ctttttgaaa agagataccc agttttttta
     2821 gtagttcata agcttcttgt tcggttgcac gactcatcgc gcatcaccct ccttttttta
     2881 ttagtgtatc ataaaaaaga gttgacaaat gaaaaataat catgtaaatt acacgtaaag
     2941 ttaaaacaaa tgacatcgaa aagaagagta gccgttaggt gtttttagag agtctctggt
     3001 tggtggaaag aggcagcagt taaccgtgaa acacatcttg gagtcgattt tctgaagcgt
     3061 atagtaggaa aatccgggga gcccgttaca gctgcggtcg ttgctagatg accagataag
     3121 gctggctttt ccgtgaggag tcggtaaaaa aaggtggaac cacgtgatta acgtcctttg
     3181 atcttcggat caaaggactt tttgttttca tctgaacggc aacgactgtg tgaggttttt
     3241 tctgcaagga aaaaataaac agaggtggaa ccacgtataa tacgtcctct tggcatttgc
     3301 caagaggatt tttttatttt aaaggaggaa aagaagatgg agtatttgat tgaagttatg
     3361 ccgcaattat tagtaggagc actcacaaca ttgaaattat ttttatttac cttgattggc
     3421 tcattaccat tagggattgt tttagcatta ggattgtctt tgcattttaa gccgctacgc
     3481 tacttgcttc aaacatatgt atgggttatg cggggaacac cgctgttgtt gcaactgatt
     3541 tttatttttt atgggttgcc gacgattggg atcgtttttg atcgtttcga agcagcactc
     3601 attgccttta tcttaaacta tgcagcttat tttgcagaga tctttcgtgg agggatacaa
     3661 tcgattcctc aaggtcaata tgaagcagcg caagttttgc aattaagtcc ctttcaaacg
     3721 gtgacgaaaa tcgtcatccc acaagtgaca aagattgttt taccttctgt agggaatgaa
     3781 gttatcaact tggtcaaaga ttcttccttg atctatatat taggtttagg tgacgtaatg
     3841 cgtgctggga aaatcgcgat ggaacgcgac gcgactttac tgcctttgct aggcgtggca
     3901 atcatctatc ttacattgac tggtattcta acaatcgtaa tgaaacaagt tgaaggaaaa
     3961 ttaaattatt accgctaact gataggagga agaaatatga ttgaattgaa gaaagtgaac
     4021 aaagcatttg gtgaaaaaaa aataatcaaa gatttgaatc taatcattcc agatgggaaa
     4081 acattagcta tcgtaggtcc ttccggtggc ggtaaaacca cgcttttacg tatcttggct
     4141 ggcttagaaa gttctgacag cggagaattt tatttagacg gtgtaccgtt caacccattc
     4201 gagcttaaaa tgaaagaaca agttgtagga gtcgtattcc aagacttcca gctatttcca
     4261 catctgaata tttttgaaaa cattacctta gcaccaaaaa tggtattgaa acagacaaaa
     4321 gaagaataca ccaaaaaagc agaagaatta gcggcttcat tagggattag tgatttattg
     4381 aatatctatc cttatcagct ttctggcgga caaaaacagc gggtagcgat tgccagagca
     4441 ttggctatga atccacgggt attggcttat gatgaaccaa caagtgcttt agatcctgaa
     4501 ttacgccagc aagtcgagcg tttgatccta tcattgaaag aagatggggt aacccaaatt
     4561 attgtcaccc atgatttagt atttgcagaa aatgtcggtg atcaattact aaaagtttcc
     4621 ccaattcatt aagaaaggag aagatagaga tgaaaaaaac cagttttcta ttcgctttga
     4681 tcgcaggtct tcttcttttt gcaggctgtt cgaacaaaaa aacttcagca gataattggg
     4741 cgactatcaa cgaagagaaa aaaatcgtta taggtttaga cgatacattt gttcctatgg
     4801 gatttagaga taaagacggg aagctcacag gatttgatat tgatttagcc aaagcagtct
     4861 ttgaacaata tgggattacg gtagactttc agcccattga ctggtcaatg aaggaatttg
     4921 aactgaacaa tggaacgatc gatttgatat ggaacggcta ttccaaaacg ccggcaagag
     4981 aaaagaaagt gcaatttaca aaaccttata tggaaaacga tcaagtgctg atcacaccta
     5041 aagaatcagg aatcacaaac tttggacaaa tgaataataa gagattaggt gcgcaaaatg
     5101 ggtcatctgg ttatgatgta tttacgaaac aaccagaagt attaaaagag atagtcaaaa
     5161 accaagatgc tgttttgtat gatagtttta atgaagcatt gatcgatctg aaaagcagac
     5221 gggtcgatgg tctgctgatg gataaagtat acgcagacta ttatttgaaa caaagaaacg
     5281 aactagaaga cttcaacata acaaaaggtt cttatgagag tgaggatttt gcagttggtg
     5341 cacgcaagtc agatagtaca ttagtgaaaa aaatcaatga agccctagat caactagaga
     5401 aaacaggtga attccaaaaa atatccgata aatggtttgg cgaagatgtt acgccgagaa
     5461 attaacaaat aggggactgt gacaaaagac gtgtcacagt ccctttttcc gaataaacag
     5521 tgttctcctg ccaactcctt gtgactcgga gctgaatggc aggctcacaa cctcttggta
     5581 aacggtgttc aaaagccagt ttttcggtat taagccaaat ttatgcaaaa atgtagaaag
     5641 ccattttcac aaaatttttc ttactactcg aaactaagcg actttttcac aacctccttt
     5701 acatattttt attttgttgt ggaaggggtt tcgtgttatt ctaaaagagg aacgattgaa
     5761 ggttatagga aaggaagaga tgaatggaac acaaagaact tacctcattt ccaaaagatt
     5821 ttctgtgggg ctctgcttct gcagcgtatc aagtagaagg agcttggcaa gaagatggga
     5881 aaggagaatc agtctgggat cgatttgtac ggatacctgg aaagacattt aaaggaacga
     5941 acggtgattt ggcagtagac cactatcatc gttataaaga agatattgct ttaatgaaag
     6001 aacaaggtct gaaagcttac cgcttctctg tagcttggac acggattttt cctaatggac
     6061 gaggagaagt caatcaagct gggctcgctt tttatgagag attgatcgac gaattgattg
     6121 aaaacgatat tgaacctatg ttgactttat atcattggga tcttccacaa gcattgcaag
     6181 atgaatataa tggttgggaa tcacgtcaga tcattgaaga tttcactcat tatgcagaaa
     6241 cattatttga ggcattccgc gggaaagtcc attactggat tagtttgaat gaacaaaata
     6301 tcttcacttc attaggttat ttgttagcag cacatccgcc aggtgtgaca gacccgaaac
     6361 gaatgtatga agttaaccat attgctaatt tagcaaatgc atctgtcatc aataaatttc
     6421 acgagttaga aatgcctgga aaaatcggac caagctttgc gtatacgcca aattatccaa
     6481 ttgacagtaa tcctgaaaat gttctggctg ctgaaaatgc agaagacctg atggccaatt
     6541 attggatgga tgtctatatg tggggaaaat atccgattgc tgccatgagg ttcttagaag
     6601 aaaaaggatg ggcaccaacg attgaagctg gcgatgcaga attgctagaa tctgctaaac
     6661 cagattttct tgggatcaat tactatcaaa cggcgacgaa tgcattcaat ccattaaacg
     6721 gagttggtgc tggaaaaatg aatacgacag gaaaaaaagg ttcatcagaa gaaactggag
     6781 ttcctggaat gtataaaaaa gttgagaatc catttgtcga acgaacaaat tgggactggg
     6841 agattgaccc agaaggatta aggatcggac tgcgtcgtat cacaagccgt taccgcatgc
     6901 cggtactgat tacggaaaat ggcttaggag agtatgacaa gttgacagaa gataaacaaa
     6961 tccatgacga ctatcgaatc aattacttac aaagccacgt caaagccatc aaagaagcaa
     7021 tttcggatgg agcagaagtc ctaggctatt gcacctggtc ttatacagat ttgcttagct
     7081 ggctgaacgg ttatcaaaag cgatatggat ttgtatatgt tgatcaagac gaaacacaag
     7141 aaggatcttt ggaacgatat aagaaagaca gttattactg gtaccaaaaa ctgattgaag
     7201 aaaatggaga gaacctttag ttcacatact taaaacaaga aggtacggct ggatatggcc
     7261 gtgccttttc ttgataaaat catttagaaa ttaagaaaaa ctgtaaaata agctgaaaaa
     7321 tgaaagaaag cgtcagttct ttcaaacaaa actttagttc ccttactttt ttttgtataa
     7381 tgaaacttga tgaaatgagg gataataaat ggcacaaaag aaacggccta ctaaaaaaag
     7441 gaaaaagacg aaaaaaacga aaaagcaaaa acagcagcag gaacaaatgc tgacgattgg
     7501 tgttgggttt gccttgattt tatttgctgt cttcggcttt ttaaaattag gttttttagg
     7561 aatattgatt gcaaacggct ttcggatcat tgcaggaaat acttaccaaa tcctctgtct
     7621 tttattagcc gtattaggat tttggattgt cattaagaat acagagtttt caattggtaa
     7681 aaaccgacgc tggtttggcg gcatactctt ttatttcggt atcttattat tgttacatgc
     7741 ccatttattt ggcaaactcc atactgggga accaaatatc atggggacga catgggattt
     7801 gttagccagt gatataaaac aaagtcaagt agacaataac gttggtggtg ggatgattgg
     7861 agcaatcctt tatcatttta cttacttctt gattgcacag cctggaagtt atttagcagc
     7921 agtgctatta ctggcaggag gagcattcct gttcagtaat ctggaaggct atcagctgtt
     7981 aaatggtatc caatcaattg gagaacgagt acaggaatta ttggaaggtg atcctgccaa
     8041 gcaagctcga aagcaagcgg caaaggaaga gagaatgaaa cagcgcgcag aagcgaaaga
     8101 agcaaggcgc ttagctgcaa aagaagctgc agaaaaagaa gctgcagaat atgagaagaa
     8161 aaaagcggtg agccagcaaa gggaaaatac tgctgatgaa tggcaggaac cagaaaatac
     8221 agagccggag cagctaagtt ttgttccaat cgacagtttt caagaaaata tccatcctgc
     8281 gaatctagag aaaccagtac cagatacacc aaaacagacc aatacagcag aaggtttttc
     8341 agatgagttg ccagaggatg acggtacctc attagaattt gagattgaag cagaacagga
     8401 aaatcaagac tatgaattac cgacagttga tttgcttgat tctataccaa ctgtggatca
     8461 aagtgatgag tataaaaaaa ttgaaaaaaa tatcggcgta ttagaacaaa ctttccaaag
     8521 tttcggtgtc gatgccaagg tcgtcaaagc cagcttagga ccatccgtca caaaattcga
     8581 agtccagccg gctgtagggg taaaagtaag taaaattgtg aacttaacag atgatatcgc
     8641 gcttgcttta gcggcgaaag atgtccggat ggaagcaccg attccaggta aatcactgat
     8701 tggtattgaa gtaccaaatg gaaagatcag tatggtttcc tttagagaaa tcatcgaagc
     8761 acaaccaaac cacccagata aattactaga agtaccttta ggacgtgatg tttctggacg
     8821 ggtacaaacg gctgatcttt cgaagatgcc tcacttactc gtggctggtt cgactggtag
     8881 tgggaagtca gtagcaatta atgggattat cacaagtata ttaatgcgtg ctaagcccca
     8941 tgaagtaaaa ctgatgatga tcgatccgaa aatggttgaa ttgaatatgt acaacggcat
     9001 acctcatctg ttgacgccgg tcgtgacgaa ccctagaaaa gcagcgcaag ccttacaaaa
     9061 agtagtacaa gaaatggaag aacgatatga aaaattcgcg gcaaccggag taagaaatat
     9121 ttctggttac aatgaatttg ttcaacagaa aaacttggaa aacggaacga aacatccaac
     9181 cttaccattc atcgtagtga tcgtagatga attagctgat ttgatgatgg tagccagcaa
     9241 tgaagttgaa gatgcgatta ttcgtttagc gcaaatggct cgggcagcgg ggattcatat
     9301 gatcctagct actcaacgtc caagtgtgga tgttatcaca ggaatcatca aagcaaatgt
     9361 accttccaga atggcatttg cggtatcaag cggtacagat tctcggacga tcattgattc
     9421 taatggggca gaaaagctct tagggcgagg agatatgcta ttcttgccaa tgggtgagaa
     9481 taaaccgatc cgtgtgcaag gagcattcat ttctgaccac gaagtagaac gggtcgttca
     9541 atttgttaca gatcagcaag aagctcatta tgaagagaaa atgatgccga cagatgaagt
     9601 tgaaacgaca ggtgctccag aacagccaca agatgagctg tttgaagaag caaaagcact
     9661 tgtcgttgaa atgcaaacgg caagtatttc ccttctccaa agaagatttc ggatcggtta
     9721 caaccgagca gcacgtttag tagatgaact ggaagctcat ggagttgttg gcccgtcaga
     9781 aggaagcaag cctcggaaag tattcattga gcaggaagaa acatcagaaa cgttgccgga
     9841 cgataatgac atgtaaaact tgtgtgatga agggttgaaa aacgaataac caataaaaag
     9901 acaaggcatg atgataccaa aagaaaaaat ggtttttttc catcttttct aatacggtat
     9961 gatgtcttgt ctttttagtt tttgtgagat taaagttcta ttcgatttat ttgtgaagta
    10021 ttgcattaag gaaatgaatc atgtatagta tgtagcgaaa ctttgagaaa aagagggaaa
    10081 atactttgga aaaacagtcc atttatggct tgacgaatga agaattaatc aattggttta
    10141 tagaaaacgg cgagaaaaaa ttccgagctg cccaagtttg ggaatggttg tatcaaaaac
    10201 gtgtaagtaa tttcacagaa atgacgaatc tatcgaaaca attgatcgaa aaattatcgg
    10261 agcattttat catcaatcct ctaaaacaga tggtcgtcca agaagcttcg gatggtacag
    10321 taaaatattt gtttgaactc cctgataaaa acatgattga gactgtactg atgagacaag
    10381 aatatggctt gtcagtttgt gtgacgacac aagtaggatg taatatcggc tgtacgtttt
    10441 gtgcaagcgg gctgctcaaa aagaaccgtg atctgactgc tggagaaatt gttgcacaga
    10501 tcatgatggt ccaacattat tttgatgagc gcaatcttgg cgaacgcgtt tcacatgtcg
    10561 ttgtaatggg gatcggtgag ccatttgata attacgacaa tgtaatggac tttttgcata
    10621 tcatcaatga tgccaaagga ttggcaattg gtgctcggca cattacagtt tccactagtg
    10681 gattagcaca caaaatcaag gaattcgcta ataacggctt gcaagtcaat ctggctattt
    10741 ccttgcacgc gccgaataat gaggtgcgaa catcgatcat gcggatcaac cgaagtttcc
    10801 caattgagaa attgatggaa gctgtggatg agtatttaga gaaaacaaac cgtcgaatca
    10861 cgtttgaata tatcatgttg aatcaagtaa atgatagacc agagcatgcg caacaattag
    10921 cagatctatt aaaagataag aaaaaattag catatgtcaa cttgattcca tataatccag
    10981 tcagtgaaca tgatcaatat tctcgcagtc caaaagctga tgtattgaga ttttatgatg
    11041 tattgaagaa aaacggcgta aactgtgtga tacgtaaaga acatggtaca gatattgatg
    11101 cagcttgcgg acaattgcga agcaagcaaa tgaaaaaaac agttgccaaa taatcgtatc
    11161 ctactcgttt tttcaattac cataaaagga gcagttttct taattaagga actgttcaac
    11221 ttaaataaga gaaaagattc tatagcgaaa gctataaagc tttttttgac aagaaaaacc
    11281 ctcatcaagc aaagaaatgt cctcaatttg atgacagcct gcttgatggg ggttttagca
    11341 attatttaac tgattttctt atatccttgc tggctttctt gtgtagcatg ataagtttct
    11401 acgtcaagaa tggcctgttt aaatttttct cgggtgattt cataaggcac atgtttaata
    11461 tcatttgttg ccatggcttt atctaagatt gcttctaaat cggtcgtgac attgagattc
    11521 atgtcggtta acgatactgg aagttggttc tttttcataa acacatagat tttatcaaac
    11581 aaatcgaact gctgatccat catcaataag gtcagtacac cataactgac agatgctccg
    11641 tgaaggtatc cctccatttt ttctagaaca gtcgtaccgt aatagaatga gtgtgccata
    11701 gcagaattat agttattgtt aactaaaaca gaaaccaatc cggtagtaac aatgatatcc
    11761 gaaacgactt gttcaattgc atatgaggga cgatcgtcgg cactatcttt caatgcttgc
    11821 gtaccataag tcaagagacg atcaatgcac atttttccga tttggattcc taatctatcc
    11881 gtgtagccta gatcatcgcc acgagcagaa aaagtagatt cgacttcttt ggataaagca
    11941 tcgccaatac ctgcccataa gtatttatca ggtgcttcgg caataattgc tgtatcaatg
    12001 aaggtgtgta caggtggttt tgaaggaaag aagagtccgt ccattacgcc ttcttcgtta
    12061 tagatgacac ataccgcagt gacgggcgaa cagttcgaac caatagtggg aaaggtgaag
    12121 actggtttag ctagtttttc accaatgact tttacagtat cgcaagcacg gccaccaccg
    12181 actgcaaaca ggacgtctgc tttttggaca ctttcatgct ggatcaactg ttcaatattt
    12241 ccataagttg aattaccccc gtaccagaga ctggcgacaa cctctatttc ctgtgtcaaa
    12301 gctactttta ttttgttttc tgcctttgaa agtgcagtct tccctccaat cagcactact
    12361 tttgtcccat attctttgac gattccattt gctttttcat acgcatctgt tccaatggta
    12421 taatttggta agaaaacact ttgactcata ttcatttcct tctttcttcg ttgaaacggg
    12481 ttaaaatttt aaagagtgat cgatctgact gcggctgtag atggagtaga ggtgaaccta
    12541 agacaggata agtgatgaat aaggtggcat gaacaccttg aaatcatcaa taagtatcct
    12601 aaaaacgaac aagtacaaaa acattgaaaa cgacaataat gaatttttgt tcctcttagt
    12661 atttctaccg attccctttg cttttttgta attatctaaa aattctaaaa attaagatta
    12721 ttatatgaaa acaggtttta tttgtcaatt cataattggt tttttttaaa gcaaaagata
    12781 atctatatca tgatgaacaa acagagtttt ttcctccaat tgatggcttt cctgatcttt
    12841 cctattttga ataaagtgtt tctgtataat ttttttattt tataagtaag ataaataatg
    12901 aaagaataga gatactgatt ggtagctaaa gatttttgag cgagaacatt tcgttttttc
    12961 aaaaggactg ttagaataag caagaacaag ggggaagacg tatgataatc agtgaatttg
    13021 accgtaataa tccagtattg aaagatcagc tttctgattt actgagactg acttggccgg
    13081 aagaatatgg agacagctcg gcagaagaag tagaagaaat gatgaatcca gaacgaatcg
    13141 cggtagcagc ggtagaccaa gatgagttag taggatttat tggtgcaatc cctcaatacg
    13201 gtatcacagg ttgggaattg catccattag ttgtagaaag ctcccgacga aagaaccaaa
    13261 taggtactcg attagtcaat tacttagaaa aagaagtagc ttccagagga ggaatcacga
    13321 tttatttagg tacggatgat ttagaccatg gaacaacgtt aagtcaaacg gacctgtatg
    13381 agcatacatt tgataaagtg gcttccatcc agaaccttcg tgaacatccg tatgaattct
    13441 atgaaaaatt aggttataaa atcgtaggtg tcttaccaaa tgcaaatggc tgggacaaac
    13501 cggatatttg gatggcaaaa acgattattc ctcgaccaaa ttctcaataa taaaaagagg
    13561 ttgtgacaga agtaatcagc ttcaagaaat aagaaggaat ttacgaaaat tacttcttga
    13621 atttttgtga aattccaact tatttccgaa gaagctactt ttggaacacc gtgtac
//
LOCUS       DAZKKZ010000070        13431 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.072, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000070 DAZKKZ010000000
VERSION     DAZKKZ010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13431)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13431)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13431
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.072"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(91..633)
                     /locus_tag="ACG8LA_002346"
     CDS             complement(91..633)
                     /locus_tag="ACG8LA_002346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2179 domain-containing protein"
                     /protein_id="HFQ0204625.1"
                     /translation="MIDPKMLGMIFLINFAYITLNTLRFMLTMKGYRLIAPLVSMVEI
                     TIYIVGLSLVLDRLDNPLNLFVYALGYAVGISVGILIEDKLALGYIMVTTILPANSAE
                     DKSLPGILREHGYGVTQTSAMGLEGERLVLEILSPRKSERELYRLIKEIEERAFIISY
                     EPKYISGGFWTKKVRKRQGK"
     gene            768..1157
                     /locus_tag="ACG8LA_002347"
     CDS             768..1157
                     /locus_tag="ACG8LA_002347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204626.1"
                     /translation="MKTVNRVFCASHVLSLLLSIYLGVYSIQQPIEVENIVFQMSLTD
                     GLILSVFFFLILFIGNIFGSVASFLNFSIYPLLSLALGVVGLCSLCLFPEPFSPAFIL
                     FGTLNLFQTTVGAWLLWRSGNLMKIGE"
     gene            1161..1925
                     /locus_tag="ACG8LA_002348"
     CDS             1161..1925
                     /locus_tag="ACG8LA_002348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HFQ0204627.1"
                     /translation="MNPIILKRSVHHIPVLEVVLKELREERIPVVIYYHGWQTSKELV
                     LTQGRKIAQQGIRVILPDAMNHGERKQPVSSIPSYTFWDSIYGNLFEFDTLIKHLEKR
                     GLLHDQLAVGGVSMGGMTTCALLAKHPHIVAGVCLMGSPAPLEYGKEIVRRASEYNYV
                     VPKDYFDLISWVKSYDLSLQPEKLAGRPLFFWHGQADEKIPYIQTERFVEKNRHKSYG
                     KEIVFRSSKTQRHMVQIPLMEEASTFLAKNLIKKYK"
     gene            2054..3001
                     /locus_tag="ACG8LA_002349"
     CDS             2054..3001
                     /locus_tag="ACG8LA_002349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFQ0204628.1"
                     /translation="MPTLADVAKRANVSKMTVSRVINHPEQVTDELKELVFSAMAELD
                     YRPNIAAKALVTNRSQIIKLFILEEIDTTEPYYMNLLMGIAKRIGKAHYSLQLVTNDA
                     FDVGSCDGYIITGVRKKDFDWIDRLEKPVVLFGENSEGYDYVDSDNEYGTAKATQYAL
                     ERDYQTIIYIGIEVDEPFEISRETGYLSVMKEVDLPSKILRFPNHSTEVERYMTENWA
                     DFTDKTCFVCSSDRLALGAVRGIINAGGHLPEEFGVIGFDGVFLDQISSPKLTTIKQD
                     IIRMGEVCGEMLLKKIEEKGASQGYRRFFPELVIRETTN"
     gene            3131..3871
                     /locus_tag="ACG8LA_002350"
     CDS             3131..3871
                     /locus_tag="ACG8LA_002350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204629.1"
                     /translation="MKEIRRKHFRFPAYDDELGVKLTNDKKRVLFDGQEDLLTEQNQS
                     PFEQMKEFHFTNTNTEKIRRKRRATNGLKSAPRKENLEKHKGKLPDYTGHYQSEITST
                     GRKKLFGDSSRSVRQSETRTESKHTTRNASVDTKVRERSYFVPKYVPASIIPDPRESK
                     ISEDHLIESMKKTDDSYLLFDTEPTPYQEKRNGEPSVRTFNRTKTLEETKQSEEKKSK
                     KSHGILERSLQGLIDDQGNSLGENSYFK"
     gene            complement(4162..4830)
                     /locus_tag="ACG8LA_002351"
     CDS             complement(4162..4830)
                     /locus_tag="ACG8LA_002351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFQ0204630.1"
                     /translation="MKKLNLFTELCGIILGAGIYGLAVTGINIPSKLADGGVTGIALL
                     LHNLFGFAPSVTSLLFNLPLLLISLFLFGKHAFLRTIVGTFALVFFLHLWESLHIHFA
                     VDSLLINSLMTGILSGIGCGLVFRFGGSTGGTDIIYQAIEKYFHIKIGKSLFLITFGI
                     LVVSLLYLDLTHFLYTLLSCSILSYTLNKVKYLEIGSVLPQLEAKQTTETFEPLDPLE
                     QLEH"
     gene            4964..5251
                     /locus_tag="ACG8LA_002352"
     CDS             4964..5251
                     /locus_tag="ACG8LA_002352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204631.1"
                     /translation="MRAADLLTILTKSPKKTEYQGVFLAQEQKLVPVTMVQINKANQF
                     IFLFEHGKAPLAMKDIFLFLMKNREKAVYYQSKEELIPLYGVKEIENKVVI"
     gene            5667..7205
                     /locus_tag="ACG8LA_002353"
     CDS             5667..7205
                     /locus_tag="ACG8LA_002353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HFQ0204632.1"
                     /translation="MNNFIQTLSERKGELLEAAFQHLSISLISLLIAALIAIPLAIWA
                     ANHKKMAEVLLQITGVLQTIPSLALLGLLIPFVGIGTVPALIALVIYALLPIFQNTYI
                     GLAEIDPSIEEAAVAFGMSRMRRLLKVELPIALPVIISGIRTALVLIIGTATLAALIG
                     AGGLGTFILLGIDRNTPVLTLIGAISSALLAIIFSGLIRWLQHKKPRYSIITLAAVVC
                     LFGGVSLYQSALFKNETITIAGKLGAEPEILIQMYKELIEDNTKTEVELKPNFGKTSF
                     LFNALDQGQIDIYPEFTGTVLESLVKVPEAMKSADLTKEKTYDEAEELLNKQFDMTLL
                     KPMAYQNTYALAVKRSFANEHQLKKISDLAAISDQIKAGFTLEFIDRSDGYKGIQEAY
                     GLNFSSVQSMEPSLRYQAINNGDVNIVDAYSTDSQLKEYDLVTLEDDRGLFPAYQGAP
                     LMKKDFAKEHPEIVKALNKLSGKITEDQMIDMNYQVNVEKKKPTEVARIFLKNEGLVK
                     EEDQ"
     gene            7202..8167
                     /locus_tag="ACG8LA_002354"
     CDS             7202..8167
                     /locus_tag="ACG8LA_002354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0204633.1"
                     /translation="MTKLIEFKHVQKKYDGKYVIDDLNLAIKKGEIFVLVGPSGSGKT
                     TTLKMINGLSKPSAGDIYFKGKSLNEYNLQKMRWNMGYVLQQIALFPTMTVKQNIEVI
                     PEMLGWEKQKRADRVDELLQKVGLSPDIYRDRMPRELSGGEQQRIGIIRAIAASPDVI
                     LMDEPFSALDPISRNSLQELVLSLHEELGTTIVFVTHNMEEAIKLGDRIAFMKDGEII
                     QCDTPEQLLMNPKNDYVRHFFDEPKQTKEWRVEDLVVNGYFLNEIPENARQQVCFDTP
                     MKEVYSLLSVYPSIVIVEKQRSIGSLTSKEIFAFLSREEEGNENI"
     gene            8154..9476
                     /locus_tag="ACG8LA_002355"
     CDS             8154..9476
                     /locus_tag="ACG8LA_002355"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HFQ0204634.1"
                     /translation="MKTYDAIIIGSGVSGLSAAYGLKEAGKTVLVVEEDLWGGTCPNR
                     GCDPKKVLLSAVEARNRVKQLSGKGFNEIPTANWEELQKFKRTFTDPVPESRKKQLAE
                     AEIDHLSGTARFLDDSSIEVNEEVFHADYLVLATGQRPTILPVEGKEYLKTSADFLSL
                     PVLPKEIIFIGGGYIAFELATIANAAGSKVTIVHHNQRPLKEFEASLVEEAVHQMEAS
                     GIQFAFGVETQKIISEGTRYRLVGKETELVADMIFCATGRQPNTESLALEQANIVFDK
                     HGIAVNDYLQTSNPKIFACGDIVSRKTPKLTPVATFEGNYVAKRITDATSEPIKYPII
                     PTIVYASPKLAEVGVTKSHASSSDQVVEMDLTSWFTYHRVNEPVAKAELTFDQQNYLI
                     GAAVISEQADELIDDLTLVINQKLTKKELDSYIMGYPTLASDLSYLLK"
     regulatory      9539..9643
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            9717..10460
                     /locus_tag="ACG8LA_002356"
     CDS             9717..10460
                     /locus_tag="ACG8LA_002356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFQ0204635.1"
                     /translation="MKKNLYPAVSMAFILIIWQIVVIVWKIPAFILPGPAAVFSALAA
                     DAQVLLSHSVTTLNEAVLGLVIASVLSFITALAMDYWKFLEMSFYPLLVISQMLPIMV
                     LGPLLTLWFGFGMLPKVILVVLISYFPIVVSFSDTLRKVSKEQIIFLKTMGADTGKIY
                     RIYKIPAGLSGFFSGLKVAATYCVSGAVVGEWLSAQAGLGYYMIRVKNSYQIDKVFAA
                     IICVILLSLLLNGACSLLKKGYYRMLYIF"
     gene            10475..11467
                     /locus_tag="ACG8LA_002357"
     CDS             10475..11467
                     /locus_tag="ACG8LA_002357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFQ0204636.1"
                     /translation="MKKLWLLLPLLLLLSACGTAKETSSKQEIKDLKKVTLVLDYVPN
                     TNHTGIYLAKEKGYYKEAGLNVQIIEPGDNSTSIGLVGADKAQFGVSYQEDVTYAHAD
                     GQNIPVKAIATVIKHNTSGFATLSDSNIHSPKDFEGKTYAGWQSPSEEAVLKAVMEKD
                     GGDFSKLTMVGSNGEGPESLGKSSDIQWYFEGWDMIKAKEAGIELNYIPLKELDERLD
                     YYTPVIITNDQLIKSDPELVQSFMDATKKGYQEAIKDPNDSAKLLQKYAKENDRTFLE
                     ESQAFLSKNYTDDPENWGLMEEKVWRNYTAFMQENGLIKQDVPSQELFTNQFIK"
     gene            11479..12216
                     /locus_tag="ACG8LA_002358"
     CDS             11479..12216
                     /locus_tag="ACG8LA_002358"
                     /EC_number="7.6.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0204637.1"
                     /translation="MSIQISHLNVVIENLKILEDIHFTIPKDTFTSIVAPSGAGKSTL
                     LKTLTGVQPMTSGTIKVDDQKVTGLHTAFSYMPQEDMLLPWLSVYQNVTLYQKINHLT
                     INEEQVRDYLDIFGLNGYEHFLPEQLSGGMKQRTALLRTIMNPSSYLLLDEPFGALDA
                     MTRGQMQDWMLKLPKKAKRTTLLVTHDIEEAIYLSDRILVLSARPAHVIAEIQVPEKR
                     RSREWLLQQSELKQTIYQLLAGELDVK"
     gene            12206..12928
                     /locus_tag="ACG8LA_002359"
     CDS             12206..12928
                     /locus_tag="ACG8LA_002359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HFQ0204638.1"
                     /translation="MLSDAHCHLDGSQSLALLQQEHTILTIINCDSPEEWKENRQLAA
                     SKTQALSYGIHPWKADSYTFEQVEPFLKKARIIGEIGLDNIWTNVPMTTQKKVFERQL
                     AFAAINEKPVVLHTKGCEKEILNYIQAYPNHYLIHWYSSLDYQQDYIDLGCYFSIGLD
                     LKKNPAVWQLAKAVPIDHLLIETDGLHAAEWALGGIFSEKDYVSLLEEQLKTIAEIKE
                     LSVEEVKKNTYQNLERFIRLGK"
     gene            complement(13012..>13431)
                     /locus_tag="ACG8LA_002360"
     CDS             complement(13012..>13431)
                     /locus_tag="ACG8LA_002360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M23"
                     /protein_id="HFQ0204639.1"
                     /translation="YSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEQPVVQETVQTEK
                     QAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTATNGRYIGRYQLDSSYL
                     NGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
BASE COUNT         4426 a         2296 c         2789 g         3920 t
ORIGIN      
        1 atgtcgatgt tttttaatca aaataataaa taaaaactgt ctaacattta aaatttaatt
       61 tagatattag acagttttta agtttgtgag ttattttcct tgtcgttttc tcactttttt
      121 agtccagaaa ccacctgaaa tatattttgg ctcataagaa atgataaaag cacgctcttc
      181 gatttctttg atcaggcgat acagttcacg ttcgcttttt ctaggagaaa gtatttcgag
      241 aactagccgc tcaccttcca gccccattgc agaagtctgt gtcacaccat aaccgtgttc
      301 tctcagtata cccggcaaac ttttatcttc tgcgctattt gctggcaaaa tcgttgtgac
      361 catgatgtat cctaatgcca atttgtcttc aatcaaaatt ccgacactga tacctactgc
      421 gtaacctaac gcatagacaa ataaattcag tggattatct aaacgatcta aaacaaggga
      481 taagccgacg atataaatcg tgatctcgac catactgaca agtggagcaa tcagtcgata
      541 gcctttcatt gtcaacatga aacgtaacgt gttcagagtg atataagcaa aattaatgag
      601 gaagatcatc cccaacattt ttggatcaat catttgtaaa actcctttca tttatataac
      661 aacaatatca aaaaaaatcg taagtgaaga aaaattgaaa ctttatacat acaaaaaaat
      721 gataaaatga ttataataga attataaaga taggttaggt gattaaaatg aaaacggtca
      781 atcgtgtgtt ttgtgccagc cacgtgctaa gtctccttct cagtatatac ttaggtgtct
      841 attcgattca acagccaatt gaggtagaga acattgtttt tcagatgtcg ctgacagatg
      901 gtttaatttt aagcgttttt ttctttttga tactgtttat tggtaatatt ttcggtagcg
      961 ttgccagttt tttgaatttt tctatttatc cactcctttc gctagcatta ggagtggtgg
     1021 gactttgttc tctgtgctta tttcccgagc cattcagtcc tgcatttata ttatttggta
     1081 cactgaacct gttccagaca actgttggag catggttgct atggcgatca ggaaatttaa
     1141 tgaaaatagg tgagtaacaa ttgaatccaa ttatattgaa acgttctgtc catcatattc
     1201 cagtgttaga agttgttctg aaagaattaa gagaggaacg tattcccgtt gtcatctatt
     1261 atcacggatg gcagacaagt aaggagttag ttttgacgca aggaagaaaa attgcgcagc
     1321 agggcattcg tgtgatcctg ccagatgcga tgaatcatgg ggagcgcaaa cagccggttt
     1381 cttctattcc atcctataca ttttgggata gtatctacgg aaatctgttt gaatttgaca
     1441 cacttatcaa gcatttagaa aaaagaggtc ttctacatga tcagcttgca gttggcgggg
     1501 tttcgatggg gggaatgaca acatgcgcct tgttggctaa acatcctcat atagtagcgg
     1561 gcgtgtgttt gatgggttcc cctgcacctt tggaatatgg aaaagaaatc gtaaggcgcg
     1621 catcggaata taattatgtc gtaccaaaag actattttga tttgatttca tgggttaaga
     1681 gctatgattt gtcattgcag ccggaaaagt tagctggacg tcctctgttc ttttggcatg
     1741 gacaagctga cgaaaaaatc ccttatatac aaacggaacg atttgtagaa aaaaatcggc
     1801 ataagtctta cggaaaagaa attgtttttc gttcctcaaa aacacagcga catatggtac
     1861 aaataccact aatggaagaa gcttccactt ttttagcaaa aaatttgata aaaaagtata
     1921 aataattgaa acggaaaatc actcatgacg atagaggatt ttccgttttt tattttgggc
     1981 tataataaac tctgttagga aaatttggta taattgatag taagaatgac aacatgttag
     2041 aaaggaagag agcatgccca ctttagcaga tgttgcaaaa cgtgccaatg tttcaaaaat
     2101 gacggtctct cgagtcatca atcatccgga acaggtgact gacgaattga aagagttagt
     2161 tttctcagca atggctgaac tggattaccg tccaaatatt gctgcaaaag cacttgtcac
     2221 gaatcggtcg cagatcatca aattatttat actggaagaa atcgacacaa ctgagcccta
     2281 ttacatgaat ttgctgatgg gaatcgctaa acggatcggt aaagcgcatt attctctcca
     2341 attagttaca aatgatgcct tcgacgtcgg ttcttgtgat ggatacatca tcacaggtgt
     2401 cagaaaaaaa gacttcgatt ggatcgaccg tttggaaaaa ccagttgtct tgtttgggga
     2461 aaattctgaa ggatatgatt atgtagacag cgataatgaa tatggtacag caaaagcaac
     2521 gcaatatgcc ttagaaagag attatcaaac gattatttat atcggtatcg aagtggacga
     2581 gccttttgaa atttcaaggg aaactggtta tttatctgtg atgaaggaag ttgatcttcc
     2641 tagtaaaatc ttgcggtttc caaatcattc gacagaagta gaaagatata tgacagaaaa
     2701 ctgggcagat tttacagata aaacttgttt tgtatgtagt tcagatcggc tagcactagg
     2761 agcagtaaga gggattataa atgctggagg acacttgccc gaagaatttg gtgtgattgg
     2821 atttgatggg gtatttttag accaaatcag ttcacctaaa ttgacaacga tcaagcaaga
     2881 tattatacgt atgggtgaag tatgtggaga aatgttgtta aaaaaaatag aagaaaaagg
     2941 ggcgagtcaa ggttatcgtc gtttttttcc tgaactagtt atcagagaga caacgaatta
     3001 agtcttatta ctatatatat atttatgaaa ttcatcgcta ttttcttaaa ataatcagcg
     3061 cattgctact gaaaacaatg aatctgtgct attattgaga aaagttccat ttttgagaag
     3121 gatggtttga atgaaagaaa tcagacgaaa acatttccgt tttcctgcgt acgatgatga
     3181 gttaggcgta aaattaacca acgacaagaa gcgagtatta tttgacggac aagaagatct
     3241 tttgactgaa cagaatcagt ccccgtttga acagatgaaa gaatttcatt tcacgaacac
     3301 gaacaccgag aaaatccgtc gcaagcgtcg tgcaacaaat ggattgaagt cagctccgcg
     3361 taaggaaaat ttggaaaagc ataaaggaaa attaccggat tataccggcc attaccaatc
     3421 agaaatcaca tcgacaggac gaaaaaaact ttttggtgat tcctctcgtt ctgtcagaca
     3481 aagtgaaaca aggacagagt ccaagcatac tacacgaaac gcatctgttg acacgaaggt
     3541 gcgggagcgt tcttattttg ttcctaaata tgtacccgca tcgattatcc cagaccctag
     3601 agaaagcaaa atttctgagg atcatttaat cgaatcgatg aaaaaaacgg atgactctta
     3661 tctgttgttc gatacagaac cgacgccgta tcaagaaaaa agaaatggtg agccgtctgt
     3721 acgaacattc aatcgaacaa aaacgttaga ggaaacaaag cagtcagaag aaaaaaaatc
     3781 gaaaaaaagc catggtatct tagaacgctc attacaagga ttgatcgatg atcaaggaaa
     3841 ctctttggga gaaaatagct attttaaata agtgatatac aaatttatat tcggctacag
     3901 ttggaaagga aacgctgcgg cgtttcctta ttttatactc tatccgaaag tttatatcgt
     3961 atcctcaaat ttttttgagt ttaagcgaat tttttctccc aataagtaag aaaataatgg
     4021 caaaataaaa aaacaaacta ttttcgcaga tcgtttgcaa aaatagttta tttttttata
     4081 aagaagattt tactgaataa tatcatttta gtttacataa tgatatttct gtaaattaaa
     4141 taaagtagtg aaaaataaga atcagtgctc taactgttca agaggatcaa gtggttcaaa
     4201 tgtttctgta gtctgttttg cttccaattg gggcaaaaca gatccaattt ccagatactt
     4261 cactttattc aatgtataag atagaataga acagctaagt aatgtataca gaaaatgtgt
     4321 gagatccaaa taaagcaagg agacaactaa aataccaaaa gtaatcaaga aaagactttt
     4381 gccaatctta atatgaaaat atttttcaat ggcttgataa atgatatctg ttccgcctgt
     4441 gcttccgccg aatcgaaaga cgagaccgca accaatgcca gaaagaatac ctgtcatcaa
     4501 actattgatc agtagactat ctacagcaaa atgtatatga aggctctccc ataaatgtaa
     4561 aaagaaaact agcgcaaatg ttccgacgat cgtccggaga aaagcgtgtt ttccaaaaag
     4621 aaacaatgag ataagcaata aaggtaaatt aaaaagcagt gaagtgacag aaggagcgaa
     4681 tccaaaaaga ttatgcaaaa gcaaagcaat accagtaacc ccaccatctg ccagcttaga
     4741 tggaatattg attcctgtca cagctaatcc gtagattcct gcgcctaaaa tgattccgca
     4801 caattctgta aataaattta attttttcat ttctagcctc ttttcttttg aaaattttca
     4861 gcaacttctt tattatactg acttatactc ttacttcaag aggaaaatga aaaaaaatta
     4921 tttttggctg tttcttttta tttatcaaat aaggagtgga aaaatgcgag cagcagactt
     4981 attgacaatt cttacaaaat cacccaaaaa aacagagtat caaggagttt ttttggctca
     5041 agaacaaaaa ctggtgcctg tgacaatggt ccagataaat aaagcaaatc aatttatctt
     5101 tttatttgaa cacggcaaag caccacttgc tatgaaagac atctttcttt ttttgatgaa
     5161 gaaccgtgag aaagctgttt attatcagtc aaaagaagaa ctcattcctc tttatggagt
     5221 gaaagagata gaaaataaag tggtgatata agtaaaaata agaaaacaag acgtttatga
     5281 tgtcaaaaca accatttttt acatttttgg caaaaaagtg tcatgataca gtataatatt
     5341 cgttgaacag gccaataaag gtgttctccc ccacgagatt tctactttat tggctgtttc
     5401 tttttattaa aataaaagtt gtgtgtgtaa aaaagatata gctgattcca agtgacaatt
     5461 tcgtatagat ttttatggta ttcgtagtga aaaaacgaga accaaaaagt tgatccgact
     5521 ttgttgcttg gattcttttt ttgtcagcat atttagaggt atttttttct tttttttgtt
     5581 cgtgctgtaa ggttaaggca agacaagtta gttgggaaaa aggaaagaaa tgtttatact
     5641 taaagaataa cagaaaggaa ggtcgcatga ataattttat acaaacatta agtgaaagaa
     5701 aaggcgagtt gctggaagct gcatttcaac atctgtccat ttctctcatt tctttgctga
     5761 ttgcagcact gattgctatt cctttagcga tttgggcagc caatcataaa aaaatggcag
     5821 aagtcttatt gcagatcacg ggtgtgctcc aaacgattcc ttcacttgcc ttattaggtt
     5881 tacttatccc atttgtaggg atcggaactg ttccagcatt gattgcactt gttatttacg
     5941 ctttgcttcc gattttccaa aacacgtata ttggtctagc tgaaattgac ccgtctattg
     6001 aagaagcagc ggtagcattt ggtatgtcca gaatgagacg cttgctgaaa gtagagcttc
     6061 ccatcgcatt acctgtcatt atctcaggta tccgaactgc cttagtttta atcatcggta
     6121 cggctacttt ggcagcattg atcggagcag gtggattagg gacatttatt ttgttaggta
     6181 ttgaccgaaa tacacctgtt ttgacattga ttggtgcgat cagttctgcc ttgcttgcaa
     6241 ttatattcag cggactgatt cgctggttgc agcataagaa acctcgatat tccatcatta
     6301 ctttagcagc agtggtgtgt ttatttggcg gcgtttcttt atatcagtct gccttgttta
     6361 aaaatgaaac catcacgatt gctggaaaat taggagcgga acctgaaatc ctgatccaaa
     6421 tgtataaaga attgattgaa gacaacacaa aaacagaagt tgaattaaaa ccgaattttg
     6481 gcaagacgag ttttttgttc aatgcactgg atcaaggtca aatcgatatc tatcctgagt
     6541 tcacaggtac tgtcctagaa agcttggtga aggtacctga agcaatgaaa agtgctgatt
     6601 tgacaaaaga aaaaacatat gacgaagcag aagaattatt gaataagcaa ttcgatatga
     6661 cattattaaa accaatggct taccaaaata cgtatgcctt ggcagtcaag agatcttttg
     6721 cgaacgaaca tcaacttaaa aagatttccg atttggcagc tatctctgat cagatcaaag
     6781 cgggattcac actggaattt attgatcgtt cagatggata taaaggaatc caagaagcat
     6841 atggcttgaa tttttcaagt gtacaaagca tggagccaag tttgcgttac caagcaatca
     6901 ataatggaga tgtcaatatt gtggatgcct attccacaga tagccagctc aaggagtacg
     6961 atctagtgac tctagaagat gatcgagggt tattcccagc ttatcaaggc gcaccgctga
     7021 tgaaaaaaga ttttgctaaa gaacatcctg aaatcgttaa agcactgaat aaattaagcg
     7081 gaaaaataac agaggatcaa atgattgata tgaattacca agtcaatgtc gaaaagaaaa
     7141 agccgacaga agtagcacga atcttcctga aaaatgaagg attagtaaag gaggaagatc
     7201 agtgactaaa ttaatcgagt tcaaacatgt gcaaaaaaag tatgatggaa agtatgtcat
     7261 cgatgaccta aatctggcaa tcaaaaaagg agaaatcttt gttttggttg gtccttccgg
     7321 tagtggaaaa acaactactt tgaaaatgat caatggatta tctaaaccat cagcaggaga
     7381 catctacttc aaaggaaaat cgttaaatga atataatctg cagaaaatgc ggtggaatat
     7441 gggatatgtg ctgcagcaaa tcgctttgtt cccgaccatg acagtcaagc aaaatattga
     7501 agtcatccct gaaatgttag gttgggaaaa gcagaaaaga gcagaccgtg tagatgaact
     7561 tcttcaaaaa gttggcttat ctcctgatat ttatcgagat cgtatgccta gagagttgtc
     7621 tggaggagaa cagcaacgga tcgggatcat ccgagctatt gctgcaagcc cagatgtgat
     7681 tttgatggac gagccattta gcgcattaga tccgatttca agaaactcat tacaagaatt
     7741 ggttttgtcc ttacacgaag aattgggcac gaccatcgtt ttcgttacgc acaatatgga
     7801 agaagcaatc aagctaggtg atcgtattgc atttatgaag gatggagaaa ttatccaatg
     7861 tgacacacca gagcagttat tgatgaatcc taaaaacgac tacgttcggc atttctttga
     7921 tgaaccgaaa cagacgaaag agtggcgagt agaagattta gtcgtcaatg gatatttctt
     7981 aaatgaaata ccagaaaatg ctcgtcaaca agtttgcttt gatacgccta tgaaagaagt
     8041 atattcgctt ctttcggtgt atccaagcat tgtgatagta gaaaagcaaa gaagtattgg
     8101 gtcgctgaca agtaaagaaa tctttgcttt tttaagtcga gaggaggaag gaaatgaaaa
     8161 catatgatgc aatcatcatc ggttcaggtg tgagcggctt aagtgctgct tatggattga
     8221 aagaagcagg taaaacagta ctagtggtcg aagaagatct atggggcggg acttgtccta
     8281 accgtggatg tgatcctaaa aaagtcttgt taagtgcagt agaggcacgt aatcgggtaa
     8341 aacaattgag tggaaaaggt tttaacgaga tcccaactgc caactgggaa gaacttcaaa
     8401 aattcaaacg aacatttacg gatccagtcc cagaaagccg aaaaaaacaa ttagcagaag
     8461 ctgaaatcga tcatctttca ggaaccgctc gttttttgga tgattcatct attgaagtca
     8521 acgaagaagt cttccatgcg gattacttag ttttggcaac cgggcaaaga cctacgatct
     8581 taccagtgga gggaaaggaa tacttgaaaa ctagtgcaga ctttttatca ttgcctgtac
     8641 tgcctaaaga aatcattttt atcggtggtg gttatattgc ttttgagcta gctacgattg
     8701 ccaatgctgc agggagcaaa gtaaccattg tccatcataa tcaacggcca ttaaaagaat
     8761 ttgaggcgtc tttggtagag gaagccgtcc atcaaatgga agcatctggc attcagtttg
     8821 cttttggtgt tgaaacccaa aagatcattt cagaaggtac tcgctatcgt ttagtcggaa
     8881 aagagacgga attagtagca gatatgattt tttgtgcgac tgggagacag ccgaatacag
     8941 aatctttagc acttgagcaa gcgaatatcg tctttgataa acacggaatt gcagtcaatg
     9001 attatctgca aacgagcaat ccaaaaattt ttgcgtgtgg agatattgtt tcaaggaaaa
     9061 ccccaaaatt gacaccagtc gccacttttg aaggaaatta tgtagctaag cggataacgg
     9121 atgcaacaag cgaacctatc aaatatccga ttatacctac gatcgtctac gccagtccta
     9181 aacttgctga agtaggagtt acaaaaagtc acgcctcttc gtcagatcaa gtggtagaga
     9241 tggatcttac cagttggttc acctatcatc gtgtcaatga accagttgct aaggctgaat
     9301 tgacctttga ccagcaaaat tatttgattg gtgctgcagt gattagcgag caagcagacg
     9361 aattgatcga tgatttgaca ctcgtcatca atcaaaaatt gactaaaaaa gagttggata
     9421 gctatatcat ggggtatccg acattggcaa gtgatctctc ctatttattg aaataatcag
     9481 catgataact aaagcgcttg ttgctttttc cttcttgtgc tacactttaa aaaatgaata
     9541 cctgtttctg gggatgtcgt agacgacatg agagtaagtt gtgaacttag acccattgaa
     9601 cctgtcagtt aatactggtg aagggagaaa catagcagac gcttgaagcg ggttactatg
     9661 tcgtgcccat ttcaagcgtt ttttgttatt catattagaa gaaaggaggt aacaaaatga
     9721 agaaaaatct ttatccagca gtcagtatgg cattcatttt aattatttgg cagattgttg
     9781 tcatagtttg gaaaatacct gcctttattt tacccggacc tgctgctgta ttttctgcat
     9841 tagcggcaga tgcacaagta ttactttccc attctgtcac gacattaaat gaagcagtgc
     9901 ttggtttggt aatagctagc gttctttctt ttattactgc cttggcaatg gattattgga
     9961 agtttttaga aatgtctttt tatccgttac tagtgatttc acaaatgttg ccaatcatgg
    10021 tgttagggcc attacttacc ctatggtttg gtttcggtat gcttccaaaa gtgatccttg
    10081 ttgtcttgat aagctatttt ccgatcgtag tttctttttc ggatacattg aggaaagtat
    10141 caaaagagca aatcatcttt ttgaaaacga tgggggcaga tacagggaag atttatcgaa
    10201 tatataaaat accagcgggt ttatccggct tcttttccgg tttaaaagtg gctgctactt
    10261 attgtgtcag cggagcagtc gttggagaat ggctaagcgc tcaagcaggc ttagggtatt
    10321 acatgatacg cgtaaaaaac agctaccaga tcgataaagt ttttgctgcg atcatttgtg
    10381 tcattctatt gagtttattg ctgaatggcg cttgttcatt attgaaaaaa gggtattatc
    10441 gtatgcttta tattttttaa gagaagggga tcaaatgaaa aaattatggc ttttattacc
    10501 gctactgttg cttttatccg cttgtggcac tgcaaaagaa acaagtagca aacaagaaat
    10561 aaaggatttg aaaaaagtga cacttgtttt ggattatgta ccgaatacta atcatactgg
    10621 catctaccta gcaaaagaaa aaggctatta taaagaggct ggtttaaatg tccaaatcat
    10681 cgaaccagga gataattcga caagtattgg tctagtaggt gcggacaaag cacaatttgg
    10741 tgtaagttat caagaagatg tcacttatgc tcacgcagat ggacagaata taccagtcaa
    10801 agcaattgct acagtgatca aacataatac ttctggattc gccaccctat cagacagtaa
    10861 catccattca ccaaaagatt ttgaaggaaa aacatatgca ggttggcaaa gtccaagtga
    10921 agaagctgtc ttaaaagctg tgatggaaaa agacggcggg gacttttcaa aactgacaat
    10981 ggtaggaagc aatggagaag ggccagaaag cttaggaaaa tcctcagata tccaatggta
    11041 ctttgaaggt tgggatatga tcaaagcaaa agaagcgggt attgaactaa actatatccc
    11101 attgaaagaa ttagatgaac ggttagatta ctatactccg gtaattatta cgaatgatca
    11161 actgatcaaa agtgatccag aattggtaca gtcttttatg gatgccacga aaaaaggcta
    11221 tcaggaagct attaaggatc caaatgacag tgctaaactg ttgcaaaaat atgcaaaaga
    11281 aaatgatcgg acgtttttag aagaatcaca agcattcttg tcaaaaaatt atacggatga
    11341 tcctgagaat tggggattga tggaagaaaa agtttggcgc aattatacag cttttatgca
    11401 ggaaaacgga ttgatcaagc aagatgtacc ttcgcaagaa ctattcacta atcagtttat
    11461 aaaataggag tgatagatat gtcaatccaa atcagccact tgaatgtagt cattgaaaac
    11521 ctgaaaatat tagaagacat ccatttcact atccctaaag atacctttac atcgattgtc
    11581 gcgccaagcg gagccggtaa gtcaacattg ctgaaaactt taacaggagt ccagcctatg
    11641 acttctggaa cgatcaaagt agacgatcaa aaagtaactg gtctccatac agcatttagt
    11701 tatatgccgc aagaagatat gttacttcct tggctgagcg tctatcaaaa cgttacgtta
    11761 tatcaaaaaa tcaatcatct aacaatcaat gaagaacaag taagggatta tctggatatc
    11821 tttgggttaa acggctatga acattttttg ccggaacaat tatctggcgg gatgaagcag
    11881 cgaacggcct tgttacgaac aatcatgaat ccttcttctt acttgcttct tgatgaacca
    11941 tttggagcgt tagatgctat gaccagaggg cagatgcaag actggatgtt gaagctgcct
    12001 aaaaaagcaa agcggactac tttacttgtg acgcatgata tcgaagaagc aatttattta
    12061 tcagacagga ttcttgtgct ttccgcccgt ccggcacatg tgattgctga gattcaagtg
    12121 cctgaaaaac gacggtcacg tgaatggcta ctgcagcaat cagagttgaa gcaaacgatt
    12181 tatcagttat tggcaggtga attagatgtt aagtgatgct cattgtcatt tagatgggag
    12241 tcagagttta gcactccttc agcaggaaca cacgattttg acgatcatca attgtgattc
    12301 gccagaagaa tggaaggaaa acagacagct tgcagcaagt aagactcaag ccttaagtta
    12361 cggtatccat ccttggaaag cagatagcta tacgtttgaa caagttgagc cttttttgaa
    12421 aaaagcaagg atcatcggtg aaatagggtt agataatatt tggacgaatg taccgatgac
    12481 tacacaaaaa aaagtatttg agcgacagct tgcttttgca gccataaatg agaaacctgt
    12541 tgtactgcac acaaaaggat gcgaaaaaga gatcttaaat tatatccaag cttaccctaa
    12601 tcactatttg atccattggt attcttcttt ggactatcaa caagactata ttgatttagg
    12661 ctgttatttc agcattggtc ttgatttgaa aaagaatcca gcagtctggc aactagctaa
    12721 agcagtccca atcgaccact tacttattga aacggatgga ctacatgcag cagagtgggc
    12781 tttagggggg attttttcag aaaaagatta tgtctcactg cttgaagaac agttaaagac
    12841 aatcgctgag atcaaagagc tatcagttga agaagttaaa aaaaatactt atcaaaactt
    12901 ggaacgtttc attagattag gtaaataaaa aagagatgtg acacaactag tgtcgcacct
    12961 ctttttggct ttctttgtat aaaagtaaac tgtttgatta ataaatgaat cttagtacca
    13021 accgtttgct tcccagaatg ctttcgccgc ttcccaagaa ccataacgtg aagtaacata
    13081 ttgttctgct actctttctt ggtttgcagc agagtagtca ccatttaagt aagaagaatc
    13141 taattggtaa cgtccgatgt aacgtccgtt cgttgctgtg taagaaccgc ttgattcttt
    13201 ttgtgcgatc cattcttttg cagagcttgt gcttgctgga gtagcagcag tttctgttac
    13261 agcaggagca ggttgtgttt cagcaacagg cgctgcttgt ttttccgttt gaaccgtttc
    13321 ttgtacaaca ggttgttcag cttggactgg tgcttcttga acggctgctt gaggttcagc
    13381 agctgcttgt gcagagcctt ctgttgggat tgttaattgt tgtcctgagt a
//
LOCUS       DAZKKZ010000071        13283 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.073, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000071 DAZKKZ010000000
VERSION     DAZKKZ010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13283)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13283)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13283
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.073"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(105..629)
                     /locus_tag="ACG8LA_002361"
     CDS             complement(105..629)
                     /locus_tag="ACG8LA_002361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase family protein"
                     /protein_id="HFQ0204640.1"
                     /translation="MSEEVGIILREAVPGDAKDILLMMGQVNKETEFLVLDEAELLLP
                     PETLEEELDYIYESNNNLLLLAIYEGTIIGTASVKADSQFRLSHVGEVGISILQEYWG
                     MGLGTLMLEEIISWAKEMGVLFRLELDVQVRNERAVHLYRKMGFQIEAVMPRGARTDL
                     GEFLDVYKMSYLIE"
     gene            complement(622..1095)
                     /gene="tsaE"
                     /locus_tag="ACG8LA_002362"
     CDS             complement(622..1095)
                     /gene="tsaE"
                     /locus_tag="ACG8LA_002362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HFQ0204641.1"
                     /translation="MIELSGLTMTEQFAEAIGHSAMPGDNLILTGDLGAGKTTLTKGI
                     AQGLGITQMIKSPTYTIIREYSQGRIPLYHMDIYRVAASGADLGLDEYFEGDGLSVVE
                     WGNLLEEALPEDYLELILEKSDTDLEKRYVKLISYGEQSETFKQRILEKWAENHE"
     gene            complement(1218..2198)
                     /gene="pta"
                     /locus_tag="ACG8LA_002363"
     CDS             complement(1218..2198)
                     /gene="pta"
                     /locus_tag="ACG8LA_002363"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008959 - phosphate acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006086 - acetyl-CoA biosynthetic process
                     from pyruvate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HFQ0204642.1"
                     /translation="MELFDSLRFKIVRRGIKIVFPEATDARILGAAARLKAEELVEPI
                     LVGNEEEIRNAAHARGIKTSSFTIISPDNYDKWDEMVDTFVERRNGKASKEQAEKILK
                     DVNYFGTMLTYMGIADGMVSGAIHSTGDTVRPALQIIKTKPGISRTSGAMIMVRGRDQ
                     EKYVFSDCAINVNPTAQELAEIAVDSAKTAELFDIEPKVAMMSFSTKGSAKSPEVDKV
                     VEATKIAKKLAPQYMIDGELQFDASYVPSVAQLKAPDSEVAGQATVFVFPELQSGNIG
                     YKIAQRFGNFEAIGPILQGLNKPVSDLSRGANEEDVYKLSIITAAQTLID"
     gene            complement(2351..3031)
                     /locus_tag="ACG8LA_002364"
     CDS             complement(2351..3031)
                     /locus_tag="ACG8LA_002364"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004844 - uracil DNA N-glycosylase
                     activity [Evidence IEA];
                     GO_process: GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HFQ0204643.1"
                     /translation="MKEIIHNSWQEVLSSEFSKDYYLHLREFLKKEYASQKIHPDMYH
                     IYEALELTPYEEVKVVILGQDPYHGENQAHGLSFSVQPGVKIPPSLRNIYKELYDDLG
                     IAPVQHGNLVSWAKQGVLLLNTVLTVREGQAYSHRGKGWERLTDTIIEKLNEREKPIV
                     FILWGKPAQEKIKMIDKSRHIIITSPHPSPLSASRGFFGSKPFSKTNDALLALGEEPI
                     DWQLPETV"
     gene            3157..4026
                     /locus_tag="ACG8LA_002365"
     CDS             3157..4026
                     /locus_tag="ACG8LA_002365"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFQ0204644.1"
                     /translation="MIKLIASDMDGTLLDAHMSVSPENAEAIRFANDAGVEFMVATGR
                     NYQEARAALDEVGIDCAMITLNGAQVFDKEGNSLFTVSIPNNQAISVLDILDANGIYY
                     EVATNDGLYSENQAKRIESFASMVATHLPHLTYKMAIAMASAKLELLHITYVDSIRAI
                     LEEKNLEVLKIICFHTEGPAVLGPVGKQISLLGDLAVTSSGQNNIEVNHKNAQKGIAV
                     AHVAHERGISLEEVMTIGDNFNDVSMLQVAGVSFAMGNAEIEVKDYAKYTTDTNLESG
                     VGKAILRAIAEDL"
     gene            4052..4567
                     /locus_tag="ACG8LA_002366"
     CDS             4052..4567
                     /locus_tag="ACG8LA_002366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LURP-one-related/scramblase family protein"
                     /protein_id="HFQ0204645.1"
                     /translation="MSEFFIQEKQLGRATRTIVKNEKGHSLFLMVGRWGTKGDALSLY
                     AMNGDLVAHIKQISLTFGTRFELYKEFEKVGTMQKIFNWPGDFYYIRRLHWTVQGDIY
                     NHQYQIHHFNQQIMKMDKATLFSGDYYVLDVSNDEDAPVCICIAAVLDYWLYRKDKSR
                     DKPVSYRLNLS"
     gene            complement(4614..5177)
                     /locus_tag="ACG8LA_002367"
     CDS             complement(4614..5177)
                     /locus_tag="ACG8LA_002367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFQ0204646.1"
                     /translation="MIRFARKEDAPEIAPLILVILKDMELPFLKQTGEQKTLEILEEA
                     ITDPNYRYSYSRGIVEEIDGKVAGVAYGYTDEEESIIDQPLVPILEKYQLDASTRLFI
                     DKETFPNEWYLDSISVSEDFRGQGIGSRLLEALPKLAKKANRSVIGLSVDEKNPKAKK
                     LYERHDFKVVGQRMISGHLYDHMQKNI"
     gene            complement(5232..5411)
                     /locus_tag="ACG8LA_002368"
     CDS             complement(5232..5411)
                     /locus_tag="ACG8LA_002368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204647.1"
                     /translation="MEKMKCPNCGKKFAYEEVNNVVEHNDKEMPVVCPYCRTEAARIV
                     THGYFITEKIEDFLK"
     gene            complement(5488..5997)
                     /locus_tag="ACG8LA_002369"
     CDS             complement(5488..5997)
                     /locus_tag="ACG8LA_002369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204648.1"
                     /translation="MKKMMFGVAALIVIGITGMTGLLNAAFHMDDISDQEYRISLKKA
                     AAIVKNETKEHNISAIHFAVEKDLENPTNATYEYQFFCEGQVIAVNPSTGKTTVRNDT
                     EKAAEHLFDIEKTEEFKQPQAAMKEAVSYYGKKAKVKEWTLLVKDERPYYKVRLIDGE
                     QDRQVWISA"
     gene            complement(6093..6473)
                     /locus_tag="ACG8LA_002370"
     CDS             complement(6093..6473)
                     /locus_tag="ACG8LA_002370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFQ0204649.1"
                     /translation="MNLTTIHHIAIIVSDYQKSRDFYVNKLGFEVIRENYRKERDDYK
                     LDLKLGSAELEIFGIANAPQRPNYPEACGLRHLAFKVDDIEETIAELQSLGIESEPIR
                     EDTFTGKKMTFFFDPDGLPLELHE"
     gene            6803..7552
                     /gene="pnuC"
                     /locus_tag="ACG8LA_002371"
     CDS             6803..7552
                     /gene="pnuC"
                     /locus_tag="ACG8LA_002371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015663 - nicotinamide mononucleotide
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015890 - nicotinamide mononucleotide
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HFQ0204650.1"
                     /translation="MKSYFQFLAHQLKGWPQQNYYLFFFSLGCQVMTLVNSPITWLSV
                     ITFIGTTLGVLCILSINAAKSVNGILGILSAICFIIVGFSAKNYLSIGEQIAYMITLD
                     IPVLLSKEWNHNMASKIRKFTGKSWFIAIISTFLVYLVSGFLIGRYTDDPRPWVDAIA
                     FSISLTAGIISFLRYNNQYYWWLASGLAQMVLWYISFTHGSASLAMFVNSSVYLLNDV
                     LAFTVSPWYNQKERERMQKMEEEYYNAQQHA"
     gene            complement(7873..9090)
                     /locus_tag="ACG8LA_002372"
     CDS             complement(7873..9090)
                     /locus_tag="ACG8LA_002372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HFQ0204651.1"
                     /translation="MPYILALDVSMGHSYSVLYKDDTCLFEDEIEHTQRGFHALLEEI
                     QHLPERPLIVFEATGIYSRPVEKFFQDHHFSYCLLNPLEAKKQMEESTLRSWKTDKSD
                     AHRLAQTHLKNQRQPKEVQSNFYLEMRDLARFYQEIEKKITRLRMDLHNCLQLTFPEL
                     EQFFSNRLTPYALTLIRLFPHPDFVLASTRTKIKNKLINETRKKISANRAEQKADQII
                     HYAQCAYPAVEKDSIHCQKTIYYAELLQDLLEQKKALATQMIKKAEGSPCFLLYQTFP
                     GIGALTAALLLGELGDITRFKTHKQLNAFVGIDIRRYHSGKYTGQDRINKRGNPKARK
                     IIFFTIRNMIRQQRAAPNHIVDYYYKLKKQPIPKKDKVATVACMNKLLKCMHAMVRAH
                     TEYDYAYAVSVDH"
     gene            complement(9348..10625)
                     /locus_tag="ACG8LA_002373"
     CDS             complement(9348..10625)
                     /locus_tag="ACG8LA_002373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204652.1"
                     /translation="MEEWQSVFEEWFPKEISKSYPIKISKQYTSSQRWEIYAKLTKKQ
                     RELVDKHRRYLISSRFMEEHYLAATDWVFSDFKINPFFRTKRSQQKLYCECGRELKVQ
                     YIVKSPKTGKILKLGINHFADHLHVSPTVAASIHQGMTKVDLALDELLWLKQKNIDFP
                     EGLWQKYCFVLYQNRRMKQPYLPDIKLAQRLAEFRQVEMPIYIADYQALENEIKKISE
                     HINGQSKKRQIKKELFDDFAEELVKDVEEFLINYRAFLRKDWQSIVYEEVPVHPNAYF
                     ETFISVLRKTKRQRTPEVTAQMEYFAKNQRFIQPKIYLFIWKQYCRYGFTEGFFDSIP
                     RIVRNGFLKVLRKEREAIQSADKKDRTVSKEKWQLVVKDIQSGNVQETIDKWKGKHYR
                     FTEAQKQALEYYQKLEESLRFNDEARKYLKELL"
     gene            complement(10704..11348)
                     /gene="pcp"
                     /locus_tag="ACG8LA_002374"
     CDS             complement(10704..11348)
                     /gene="pcp"
                     /locus_tag="ACG8LA_002374"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016920 - pyroglutamyl-peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HFQ0204653.1"
                     /translation="MKVLVTGFDPFGGDKVNPAYEAVKKMPDEISGAEIIKVEVPTVF
                     EKSSQVVKEAIQQHQPDVVICVGQAGGRSAVSFERVAINLAEARIPDNEGNQPFDTAL
                     EENGPAAYFTSLPIKAMTKNVQDHGLPAYISYTAGTFVCNDIMYRLLHLIETQFPAIR
                     GGFIHVPFSPDQVIDRPVGTPSMSLEDIASSLTYAVEAAVENKEDISGNAGTTH"
     gene            complement(11547..12491)
                     /locus_tag="ACG8LA_002375"
     CDS             complement(11547..12491)
                     /locus_tag="ACG8LA_002375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HFQ0204654.1"
                     /translation="MDFFTNPDILLGDKLLEILYIVMGLVLIYTGVRNLTDKTNPHRY
                     GSAFFWTVLGVVIAGGRWLPAIVNGGLIFAMTIPAIAKKVSKGESRLPSKEYMEKMSD
                     KLGMKIFIPALSIGVFAILFALFTNLGALVGVGVGVFAAMLILMFFSRDNRPSTFLDD
                     AADMLGTVGPLSMLPMLLASLGAVFTSAGVGTVISNAVGTIVPEGNVNIGIIIYALGM
                     VIFTVIMGNAFAAITVMTVGIGAPFVFSHGANPALIGMVALTCGFCGTLLTPMAANFN
                     IVPVAMLEMKDKYGVIKNQLFIALFMLVFQIAYMILFK"
     gene            complement(12493..13179)
                     /locus_tag="ACG8LA_002376"
     CDS             complement(12493..13179)
                     /locus_tag="ACG8LA_002376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HFQ0204655.1"
                     /translation="MENYLSLLGVLIVILGFAFKLDSILIVMVALVVTALTGGLGIQG
                     MLELLGTSFVNNRGMAIFIIIMLATGTLERNGLKESAASLIKRFKKVSAGMIVDIYGI
                     FRMIFAAFNVSFGGVAGFVRPIILPMALGTIESKGLEVHPKHEEELKGMASAMENVCW
                     FFGQVLFIGGAGALLVQSTLKDLGYDVTLGQLALVEVPVAITALVVASVYFYLKEKKL
                     AKKYYPGKGQ"
BASE COUNT         3775 a         2773 c         2396 g         4339 t
ORIGIN      
        1 tattcaaaaa aaatggactg cgacacgact tttgtcacag tcccttcgtg tgtttttctg
       61 ccttctcaaa aggatgacag tttctcactc ttttcctatt tcttctattc aatcaaataa
      121 ctcattttat atacatctaa aaattcacct agatctgttc ttgcccctct aggcatgacc
      181 gcttcgattt ggaagcccat ttttcggtaa aggtgtacgg ctctttcatt acgaacttga
      241 acgtcaagct ccaatcgaaa aagtacaccc atttccttcg cccaactgat gatttcttct
      301 agcataagag tgcctagtcc cattccccaa tattcctgca gaatactgat accgacttct
      361 cccacgtgag acaaacgaaa ttgactgtct gccttgacag atgctgttcc aataatcgtc
      421 ccttcataga ttgcaagcag caataaatta ttattgcttt cgtatatata atccaactct
      481 tcttctaagg tttctggtgg taacaggagt tctgcttcat ccaaaactaa aaattctgtc
      541 tccttattaa cttgtcccat catcaaaaga atgtcttttg catctcctgg cactgcttcc
      601 cgcaagatga tcccaacttc ttcactcatg attttcagcc catttttcta gaattcgctg
      661 tttgaaggtt tcactttgct ccccgtatga gattagtttc acataccgct tttctaaatc
      721 tgtatcactt ttttctaaaa tcagttccaa ataatcctcc ggcagtgctt cttctaatag
      781 atttccccat tcaacaacgg aaagcccatc accttcaaaa tattcatcta accctaaatc
      841 tgctccgcta gctgctaccc gataaatatc catatgatac aacggaatcc gaccttgact
      901 atattctcta ataatcgtgt atgtcggact tttgatcatt tgcgttatcc ctaatccttg
      961 ggcaattcct ttcgtcaacg ttgttttacc cgcacctaga tcaccagtca atatcagatt
     1021 gtcacctggc attgcggaat gaccaattgc ctctgcgaat tgttctgtca ttgttaatcc
     1081 tgatagttcg atcatttttc atcttctccc gctcttcttt ctttttgcca gtatatcgcg
     1141 taatgaagtt tttttaaaga aaaaatgaac tagtcaagaa cagcagctgc tgtttttggc
     1201 tagttcgcgt gtatttgtta atcaatcaat gtttgtgctg ctgtgataat cgataattta
     1261 tatacatctt cttcatttgc tccacgagac aaatcagaaa ccggtttgtt caagccttgt
     1321 agaattggtc cgattgcttc aaagttaccg aaacgctgag caattttata gccgatattt
     1381 cctgactgca attctggaaa tacaaagact gttgcttgac cagctacttc tgaatctggc
     1441 gctttcagtt gtgcaactga aggaacataa gaagcatcaa attgcaattc gccgtcgatc
     1501 atgtattgtg gcgctagttt tttagcgatt ttagttgctt caactacttt gtctacttct
     1561 ggcgatttcg ctgagccttt tgtcgagaag ctcatcattg ctacttttgg ttcgatatcg
     1621 aacaattctg ctgtttttgc agaatctacg gcgatttcag ccaattcttg cgcagttgga
     1681 ttcacgttga tcgcacaatc cgaaaagaca tatttttctt gatctcttcc acgtaccatg
     1741 atcatcgctc cgcttgtccg actgatgcca ggctttgttt tgatgatctg aagtgctggg
     1801 cgaacagtgt cgccagtcga atggatcgct ccagagacca ttccgtctgc aatccccata
     1861 tacgtaagca tcgtaccaaa gtaattcaca tcttttaaaa tcttttctgc ttgttctttg
     1921 gatgcctttc catttctacg ttcaacaaaa gtatccacca tttcatccca cttatcgtaa
     1981 ttatcagggc tgatgatcgt aaagctagat gttttgattc ctctggcatg cgctgcattt
     2041 cttatttctt cttcgttccc tactaaaatg ggttccacaa gttcttctgc tttcaaccgg
     2101 gcagctgcgc ctaaaatacg agcatcagta gcttccggga aaacgatttt gatcccacgg
     2161 cgaacaattt taaatcttaa actatcaaac aattccacaa gatgacctcc agacgttttt
     2221 atatgtatta tcatacacta ttccagaaaa aaagaacagt ttattttatc tgtatcagtc
     2281 aaaaatgctg gaaaaattaa gtttttcaca tacaaagcga actgcactat aacaggaaag
     2341 cgctgtttta ttacactgtt tcaggcagtt gccaatcaat cggttcttct cctaacgcaa
     2401 ggagcgcatc attcgttttc gagaagggtt tggaaccaaa aaagccacga cttgcagata
     2461 acggactggg atgtggagat gttatgatga tatggcgact cttatcgatc attttgattt
     2521 tttcttgtgc cggttttccc cacaagataa acacgattgg tttttcccgt tcatttaatt
     2581 tttcaatgat cgtgtctgtt aatctttccc aacctttccc gcgatgagaa tacgcttgcc
     2641 cttcccgaac ggtaagaacg gtgttgagta aaaggactcc ctgtttagcc catgacacta
     2701 gatttccatg ttgaacaggt gcgattccaa gatcatcata aagctcttta tagatatttc
     2761 ttaacgatgg cgggatcttt acgccaggtt gcacagaaaa agataagcca tgagcttgat
     2821 tttctccatg ataaggatct tgtcctaaaa tcaccacttt aacttcttca taaggagtca
     2881 attccaatgc ttcatagata tgatacatat ctggatggat cttttgggac gcatattctt
     2941 tttttaaaaa ttctcttaga tgcagataat aatcttttga aaattctgag gacaaaactt
     3001 cttgccaact gttatgaatg atttctttca aaaactccac ctcctaataa aaagaataac
     3061 tcacattttc ttcaatcaca agggacaatc ttcaccctca gcacttgatt aatatggtaa
     3121 actaggaaca agaagcagaa aggaacgata atcattatga tcaaattaat tgcatcagat
     3181 atggacggca cattattaga tgcccatatg agtgtttctc ctgaaaatgc cgaggcgata
     3241 cgttttgcaa atgatgccgg tgttgagttc atggtcgcta ctggtcgaaa ctatcaagaa
     3301 gctcgcgcag ctttagatga ggtaggaatc gattgtgcga tgatcacttt gaacggggca
     3361 caggtatttg ataaagaagg aaattcattg tttaccgtgt cgattccaaa taatcaagca
     3421 atctctgttt tagatattct agatgctaac ggtatttact atgaagtagc aaccaacgat
     3481 ggtctttatt ctgaaaatca agcgaaacga attgaaagtt ttgcttccat ggtggctacc
     3541 catttacctc accttacgta taaaatggcg attgccatgg cctcagctaa gctggagtta
     3601 ttgcacatca catacgtgga cagtattcgt gctattttgg aagaaaagaa tctggaagtt
     3661 ttaaaaatta tttgttttca tacagaaggg ccagctgtat taggtccagt tggaaagcag
     3721 atttctcttt taggcgatct agccgttact tcctctggtc aaaacaatat cgaagtgaac
     3781 cataaaaacg ctcaaaaagg aattgctgtt gcccatgtcg ctcacgagcg tgggatttct
     3841 ttagaagaag tcatgacgat tggcgataac ttcaatgatg tcagcatgct gcaagtagca
     3901 ggagtcagtt tcgcaatggg aaatgcagaa atcgaagtaa aagattatgc caaatataca
     3961 acggacacaa accttgaatc tggcgtagga aaagccatat tgcgcgcgat tgcagaagac
     4021 ttgtagtttt atctagaaaa gagggatata gatgtcagaa tttttcattc aggaaaagca
     4081 gcttggacgt gcaactcgga caattgtcaa aaacgaaaaa ggacattccc tgtttttgat
     4141 ggttggtcgc tggggaacaa agggcgatgc attgtctctt tatgccatga atggcgatct
     4201 cgttgctcac atcaagcaga taagcctgac attcggtacg cgttttgagc tgtataaaga
     4261 gttcgaaaag gtgggaacca tgcagaaaat attcaattgg cccggtgact tttattatat
     4321 tcgtagactt cactggacag tccaaggtga tatctataat catcaatatc aaatccatca
     4381 tttcaatcag caaatcatga aaatggataa agcaacactt ttttcaggag attactatgt
     4441 attggatgtc tcaaatgatg aagatgctcc agtttgtatt tgtattgctg cggttttaga
     4501 ttactggctc taccgtaaag acaaaagtcg cgataagcct gtttcttacc gacttaactt
     4561 aagttaaaaa gatgtacctg aaatgcggaa atacgcattt caggtacatc tttttagata
     4621 ttcttttgca tatgatcata aagatgacca ctgatcatcc gctgaccgac aactttgaag
     4681 tcatggcgtt cgtataattt tttagccttt ggattttttt catccacact tagaccgatg
     4741 acggagcgat tagctttctt cgccaattta ggtaatgctt ctaataatcg cgaaccgatg
     4801 ccttgtcctc taaaatcttc tgatacactg atagagtcca aataccattc gttgggaaac
     4861 gtttctttat caatgaacaa acgtgtagac gcatctagct gatatttctc taagataggt
     4921 accagtggct gatcgatgat tgattcttct tcatctgtat aaccgtaagc aactcctgca
     4981 actttaccgt ctatttcttc tacgatacct cgtgaataac tgtaacgata atttggatca
     5041 gtgattgctt cttctaaaat ctctaaagtc ttttgttccc ctgtctgctt caaaaatggc
     5101 agttccatat cttttagaat cactaagatc aatggggcga tttctggagc atcttctttt
     5161 ctcgcaaaac gaatcatagt ttcctctcct tttctccatt ctaacatgca gaaaaagaaa
     5221 tcgcaaaatc gttattttaa aaaatcttca atcttttcag taatgaaata accatgagta
     5281 acgattcttg ccgcttcagt tcggcaataa gggcagacga ctggcatttc tttatcatta
     5341 tgttcgacta cattattgac ttcttcgtat gcaaattttt ttccgcaatt agggcatttc
     5401 attttttcca tgttatctca acttcctttc atctttactc tcttagctta ctcttatatt
     5461 gtaaaaaaga gaagcaatat ccttcttcta tgcagatatc catacctgac ggtcctgttc
     5521 tccatctatt aatcggactt tataataagg acgttcatct ttgactagaa gtgtccactc
     5581 tttcactttt gcttttttcc cgtagtagct gactgcttcc ttcatcgctg cttgcggttg
     5641 tttgaactct tccgtttttt ctatatcaaa aagatgttct gcggcctttt ccgtgtcatt
     5701 tcgtacggtt gttttcccag tggatggatt gactgctatg acttgtcctt cacaaaaaaa
     5761 ctggtattca tatgttgcat tcgtaggatt ctccaaatct ttttcaactg caaaatgaat
     5821 agcagatatg ttatgttctt ttgtttcgtt ttttacgatt gctgctgctt ttttcaatga
     5881 gatccgatat tcctggtcac taatatcatc catgtgaaaa gcggcattga gcagtcccgt
     5941 cataccggta atccctatta cgatgagggc agcaacacca aacatcattt ttttcattct
     6001 tcattctcct gtttcttttt tttaaagaat atcaagaaat gaacgaatga aaaatcgaat
     6061 gaaacgaaaa aaaagtgaca attttgttat ctttattcgt gcagttctaa tggcaatccg
     6121 tctggatcaa agaaaaacgt catttttttt cctgtaaagg tatcttctct aatcggttct
     6181 gattcgatcc ctaaggactg caattctgca attgtttctt caatatcgtc tactttgaaa
     6241 gcaagatgac gcaagccaca agcttctgga tagtttggtc gttgtggcgc attagcaatt
     6301 ccaaaaatct ccaattcagc acttcctagt ttcagatcta atttatagtc atctcgttct
     6361 ttgcggtaat tttctctgat tacttcaaat cctaatttat taacataaaa atcacgtgat
     6421 ttctgataat ctgaaacaat gatggctata tgatggatcg ttgtaaggtt catatgagca
     6481 ctcctattct tcgtttaagc tcggatctat attaatctcc agttccattg taaatgtgtc
     6541 agattgaaaa aaatagctgt ttttcctttt tataagaaaa aaggcaaaaa aaacagaaag
     6601 taggtcctcc aagacactct tcctgttccc aatataataa atgaaagtaa gaaattatat
     6661 tttcaagaaa acaaacagaa aattatcata acacaaatta tttataattg aaagactagt
     6721 tttttttcaa gaaaagcata caatagattg tgttagtaaa tacagaacac actacattta
     6781 gtgtcttaag gagtcctcat acatgaagtc atattttcag tttttagctc atcagctaaa
     6841 aggctggccg caacaaaatt attatctttt ctttttcagt cttggctgcc aggtcatgac
     6901 tcttgtcaat agtcccatca cttggctgtc cgttattaca tttatcggta ccacgcttgg
     6961 tgtattgtgt attttatcca tcaatgcggc aaaatcagtc aacggtattt taggtatttt
     7021 gtctgcgatt tgttttatta tcgttgggtt ttcagcaaag aactatttaa gtatcggtga
     7081 acagattgct tatatgatca cattggatat ccccgtattg ttaagtaaag aatggaatca
     7141 taatatggct tcaaaaatcc gaaaattcac tggaaaaagc tggtttatcg caatcatcag
     7201 tactttcctt gtctatcttg tttcaggatt cctgattggt cgttatacag atgatcctcg
     7261 gccgtgggta gatgccattg ctttttctat tagcttgact gctggtatca tcagtttctt
     7321 gcgttacaac aaccaatatt actggtggtt agcttcaggg cttgctcaaa tggtcctttg
     7381 gtatatttca tttacgcatg gatctgcaag tttggcgatg ttcgtgaaca gctctgttta
     7441 cttgctgaat gatgtccttg catttaccgt ttcaccttgg tataaccaaa aagaacgtga
     7501 acgtatgcaa aaaatggaag aagaatacta caacgcacaa caacacgcat aaaaaaactg
     7561 agcgtgggac aaaagtaaag aacacttttg tctcacgctc taaacacgta taaacggcgg
     7621 aatcagaagc aactccttcg gaaataagct gaaattcaca aaaatttgaa aagcaatttt
     7681 cgtgaatttc ttcttatttc ttggagttaa acgcttctgt cccagcctct atttcctacg
     7741 attagtcaag taaaaggtgc aagaaaaata gctcgtaaac gaaagcgaca aaatcaaagc
     7801 acaccaaata aagccccgtt cgtaaaaaat tttcgatctg ggcaaagaag tggtatactg
     7861 taagtggttt agttaatggt ccactgagac cgcgtacgca tagtcgtact ctgtatgtgc
     7921 cctaaccata gcgtgcatac atttcagaag cttgttcata caagcaactg tggcaacctt
     7981 atctttctta gggataggtt gcttttttaa tttgtagtaa taatcgacaa tatgattagg
     8041 agctgcgcgt tgctggcgaa tcatatttcg aatggtgaag aaaataattt tccgtgcttt
     8101 gggattacca cgcttattga tgcggtcttg gccagtatac ttacctgaat gataccgtcg
     8161 gatgtcgatt ccgacaaagg cattcaattg tttatgggtt ttaaatcgtg tgatatctcc
     8221 taattcaccg agcaataaag cggctgtgag tgcgccaatc ccagggaacg tttggtacaa
     8281 caaaaagcaa ggagagcctt cggctttttt gatcatttgt gtcgccagtg cttttttttg
     8341 ttcgagtaaa tcttggagaa gttcggcgta atagatcgtt ttttgacagt ggatactgtc
     8401 tttttcaaca gctggatagg cacactgtgc atagtggatg atttgatctg ccttttgctc
     8461 ggcacgattc gcggagattt ttttccgtgt ttcgttgatc agtttatttt ttatttttgt
     8521 ccgagtagat gccaatacaa aatctggatg gggaaaaaga cggatcaatg tcaatgcgta
     8581 aggggtcagc ctgtttgaaa agaactgttc aagctctgga aaagtcaatt gaaggcagtt
     8641 gtgtaaatcc atgcgcagac gagtgatttt cttctcaatt tcttgataaa aacgggctaa
     8701 atcgcgcatc tctaagtaaa aattgctttg tacttctttt ggctgacgtt gatttttaag
     8761 atgagtctgt gcgagccggt gggcatccga tttatctgtt ttccaactgc gtaaggtgct
     8821 ttcttccatc tgttttttcg cctctaacgg gtttaacaaa cagtaagaaa agtgatgatc
     8881 ttgaaagaac ttttcgactg gtctggaata aatccccgtt gcttcaaaaa caatcaatgg
     8941 acgctcaggc aagtgctgga tctcttcgag taatgcatga aatcctcttt gagtgtgttc
     9001 aatctcgtct tcaaataagc aggtgtcgtc tttgtatagg acactgtagc tgtgtcccat
     9061 tgaaacatct aatgcaagaa tgtaaggcat ttgttttcct cctttttaag ttttgaaaga
     9121 actttactgc ttcatttcga ttccaatttc ctatacacgg gctcatggcc ccaacatacg
     9181 taaacctgat tctaaaatga cagtaaagaa gttcggtttt tgatagggac tcgtagtcct
     9241 caaggctttg ttcgaacttt ctttcactct tcactataat ctaaaaatag aaaatagagg
     9301 agaacatcat tcgtcaatga tgttcccctc taatcttagt atgtttttta tagtaattcc
     9361 ttcagatact ttcttgcctc atcattgaaa cgcagtgatt cttctaactt ctgataatat
     9421 tccaacgctt gtttctgagc ttcagtaaaa cgataatgtt ttcctttcca tttgtcgatt
     9481 gtctcttgca catttccaga ttggatatct ttcactacta gttgccattt ttcttttgag
     9541 actgtacggt ctttcttatc agcagattgt atagcttctc gttctttacg caatactttt
     9601 aaaaaaccat ttctgactat ccgaggaatg ctgtcgaaga acccttctgt aaaaccatag
     9661 cgacaatatt gcttccaaat aaatagatag atttttggtt ggatgaatcg ttggtttttc
     9721 gcaaaatatt ccatctgagc agtgacttct ggtgttcgtt gacgttttgt ctttctcaac
     9781 acggaaataa atgtttcaaa ataagcatta ggatgtactg gcacttcttc atatacgatg
     9841 gattgccaat ctttacgtaa aaatgcgcga tagttgatca agaattcttc tacatccttt
     9901 actaattctt ctgcaaagtc gtcaaatagt tcttttttta tctgtcgctt ttttgactgc
     9961 ccattgatgt gttcacttat tttcttgatt tcattttcca atgcttgata atccgctatg
    10021 taaatcggca tttctacttg gcgaaattct gcgagccgct gagctaattt tatatccggt
    10081 aaatatggct gtttcatccg acgattttgg tacaagacaa aacagtattt ttgccatagt
    10141 ccttcaggaa aatcgatatt cttctgctta agccataata attcgtctaa ggccagatca
    10201 acttttgtca ttccctgatg gatcgaagct gccactgtcg gagagacatg caggtgatcg
    10261 gcaaagtggt tgatgcctag ttttaggatc tttccggttt ttggcgattt aacgatgtat
    10321 tgcactttta attctctacc acactcacaa tacaattttt gctggcttcg ttttgttcga
    10381 aaaaacggat tgatcttgaa gtcagaaaac acccaatctg ttgcagctaa ataatgttct
    10441 tccataaaac gagagctgat tagatatcgg cggtgcttat cgactagttc ccgctgtttt
    10501 ttcgttaatt ttgcatagat ctcccaacgt tgactgcttg tgtattgttt agaaattttg
    10561 atgggatagc ttttgctgat ttcttttgga aaccattctt caaagacgga ttgccattct
    10621 tccacggctg tttctttcct ttctaattac aaaaagctgg ctactaacat aacgttagca
    10681 accagccagt gtttcttgct aaattagtga gttgttccgg catttccgga aatatcttct
    10741 ttattttcta ctgctgcttc aactgcataa gtcaaagaag aagcaatgtc ttctaaagac
    10801 atagaaggcg tacccactgg acgatcgatc acttgatcgg gtgagaatgg cacgtggatg
    10861 aacccacctc gaattgccgg gaattgtgtt tcgatcaaat gaagcaaacg atacatgata
    10921 tcattgcaga caaatgttcc tgctgtataa gagatgtacg ctggtagacc atgatcttgt
    10981 acattttttg tcattgcttt gattggcaat gaggtaaagt aagcggctgg accgttttct
    11041 tctaaagccg tatcgaatgg ctgatttcct tcattatcag ggattcttgc ttctgctaga
    11101 ttgattgcga cacgttcgaa cgagactgct gaccgcccac ctgcttgtcc gacacagatc
    11161 acgacatctg gttggtgctg ttggatggct tctttgacta cttgactgct tttttcgaat
    11221 acggtcggta cttccacttt gatgatttca gcaccgctga tttcatctgg catttttttt
    11281 actgcttcat aggctggatt cactttgtcc ccaccaaatg gatcaaaacc tgttactagt
    11341 actttcatct gttgttcctc cgtccgattg atttaacata tggttatctt ttatcatacc
    11401 attttccttg aacagcgtaa ataaaggaaa caatagttta aataacataa cagatcaaac
    11461 ttaatatatt cttataaaaa aatagtgttc cactacaatg ttagaagagg ttgcgacaat
    11521 tattctgtca caacccctct cttctattat ttaaatagaa tcatataagc aatttggaaa
    11581 actagcataa ataacgcaat aaacaactgg tttttgatca ctccgtattt gtctttcatc
    11641 tccagcatcg ctacaggcac gatattgaag ttagcagcca tcggtgtcag cagggtccca
    11701 caaaaaccgc aagtcaatgc aaccattcct attaacgctg gattcgctcc atgactaaat
    11761 acgaatggtg caccgatccc aaccgtcatc acggtgatgg ccgcaaatgc attccccatg
    11821 attaccgtaa atatcaccat gccaagagcg taaatgatga tgccgatgtt cacatttcct
    11881 tctggaacga tcgtacctac tgcattggaa atcactgtcc caactccagc gcttgtaaat
    11941 accgcaccta gagaagctaa aagcattggc aacatgctta acggccctac tgtgcccagc
    12001 atatctgctg catcatctaa aaatgtactt ggtcgattat ctcgagaaaa gaacatcaag
    12061 attagcatgg ctgcaaaaac accgacgccc acgccgacta aagcacctaa attggtaaat
    12121 agagcaaaca agatcgcaaa gacaccgata ctcaaagctg gaataaaaat tttcattcct
    12181 agtttgtctg acattttttc catatattct tttgatggaa gccggctttc tcctttgctg
    12241 actttcttag caattgctgg tatggtcatc gcaaagatca agccaccgtt cacgattgcc
    12301 ggaagccatc ttcctcctgc aataactacc cctaagaccg tccagaaaaa ggctgaccca
    12361 taacgatgag gattggtttt atctgttaaa tttcttactc cagtgtaaat caatacgagt
    12421 cccatcacga tataaaggat ctccagtaat ttatcgccta ataaaatatc aggatttgta
    12481 aaaaagtcca tcttattgcc cctttcctgg ataatatttc ttcgctaatt tcttttcttt
    12541 aagatagaag tagacacttg ccacaactaa agccgtgata gccactggaa cttccactaa
    12601 agcaagctgt cccaatgtta cgtcatatcc tagatctttc agtgttgatt ggactagcaa
    12661 cgcccctgct cctccgatga atagtacttg gccaaagaac cagcagacat tttccatagc
    12721 tgaagccata ccttttagtt cttcttcatg cttaggatgg acttctaacc cttttgattc
    12781 gatggtcccc aatgccatcg gtaaaatgat tggacgaaca aatccagcaa ctccaccaaa
    12841 actcacgtta aaagccgcaa agatcattcg aaagatccca taaatatcta caatcatacc
    12901 agcagatact ttcttgaatc gcttgatcaa ggaagccgct gattctttca gaccatttct
    12961 ttcaagcgtt cctgttgcca acataatgat gataaaaatc gccatcccgc gattgtttac
    13021 aaaacttgta cctaaaagtt ctaacattcc ttgaatgcca agaccgccag tcaaagctgt
    13081 aacaactaaa gcaaccatta cgatcaatat cgagtctaat ttaaatgcaa acccgagaat
    13141 aacaatcaag acgcctaaaa ggctaagata attttccata tattttcctc cataaaatga
    13201 caatattttt ttaattataa agcaaaacac ataaaaaata tagttgtttt ctcacgaaat
    13261 agacactatt tttaaatatt ttt
//
LOCUS       DAZKKZ010000072        13147 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.074, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000072 DAZKKZ010000000
VERSION     DAZKKZ010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13147)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13147)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13147
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.074"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(77..149)
                     /locus_tag="ACG8LA_002377"
     tRNA            complement(77..149)
                     /locus_tag="ACG8LA_002377"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(114..116),aa:Lys,seq:ctt)
     gene            530..1099
                     /locus_tag="ACG8LA_002378"
     CDS             530..1099
                     /locus_tag="ACG8LA_002378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HFQ0204656.1"
                     /translation="MEKMRQQLMEWGKELETFRLPHWEELPDLELYMDQVRTLVDRYL
                     SPVIQGEKHPLLTSSMVNNYVKLGLIPAPVKKRYNKEHVAFLLAITTLKQVLTIPEIK
                     EGILFQGKTVGIREAYNLFCDEQEAAVWMVSQLAQGKSHPQKFDQATPVEYIAVRAAT
                     LSFAMKLLAEKTIVLETEYLKEEKTNEKQ"
     gene            1086..1946
                     /locus_tag="ACG8LA_002379"
     CDS             1086..1946
                     /locus_tag="ACG8LA_002379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HFQ0204657.1"
                     /translation="MKNNKIAILVDSGTDVPEELIKKYEMYMIPLKIIYKDQVYTDKI
                     DITSEEIYQRLPEEIPGTSLPDGESITEIFEQIKKDGYEKVLAVTISSGLSGTYNVVR
                     LIAQQQEELEAYVLDTKNIGIGAGFSAIQAAKWLEEGVEWDQLISNLNELVERTKVFF
                     NVATLEYLQKGGRIGLVASIVGTALKLNPIISCNEEGIYYTVGKARGRKKSLDKTVAY
                     VKEKIGNAKVFNLAVAHGDAKEEAIEMEARLKREFPQANQIYFGQISPALVVHTGPGL
                     LGVGVQVLEG"
     gene            2136..2840
                     /gene="yycF"
                     /locus_tag="ACG8LA_002380"
     CDS             2136..2840
                     /gene="yycF"
                     /locus_tag="ACG8LA_002380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator YycF"
                     /protein_id="HFQ0204658.1"
                     /translation="MKKVLVVDDEKPISDIVKFNLAKEGYDVYTAYDGEEALEKVAEV
                     EPDLILLDLMLPKMDGLEVAREVRKTYDMPIIMVTAKDSEIDKVLGLELGADDYVTKP
                     FSNRELVARVKANLRRGATAAKEPEEAAPAELTIGDLTIHPEAYMVTKRGETIELTHR
                     EFELLFYLAKHLGQVMTREHLLQTVWGYDYFGDVRTVDVTVRRLREKIEDNPSHPNYL
                     VTRRGVGYYLRNPEQE"
     gene            2845..4680
                     /gene="walK"
                     /locus_tag="ACG8LA_002381"
     CDS             2845..4680
                     /gene="walK"
                     /locus_tag="ACG8LA_002381"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     WalK"
                     /protein_id="HFQ0204659.1"
                     /translation="MKRKVRFFRSVNFKIAITFILILLISIEIIGAYFIRGLERSTIN
                     TFIKDMNQTVESLATTISPELNRKDNADDEEVNANIKRFIENSATSDIIEIRVVDEKG
                     IIRGTTDVNEQSAVGKKNDYVDINDFTTKRYVALDNDDKRVNINVQPILSPTGDAVIG
                     ALYVKSNIEQKYSEINNTAVIFFTASLIAAFISMIVSVLVARSITQPIGEMREQAIRI
                     ARGDYSRKVKVHGQDELGQLADTFNQLAERIEEAQDTMEAERNRLDSVLSHMTDGVIA
                     TDRRGKVITINDMAVSLLDIKNEEAIGQSILTLLDIEEEYTLRKLLEDPNEMVLDRST
                     STLESDQMILRVDFSMIRRESGFISGLVAVLHDVTEQEKTERERREFVSNVSHELRTP
                     LTSMRSYIEALSEGAWKDEEVAPNFLKVTLDETDRMIRMINDLLNLSRMDTGNTQLQL
                     EYVNFNELVNFVLDRFDMMVGNQEKNYKIRREFTQRDLWVEVDTDKIIQVVDNIMNNA
                     IKYSPDGGTITCRLLETHNNVVLSITDQGLGIPKKDLNRVFERFYRVDKARARAQGGT
                     GLGLAISREVIKAHRGAIWAESKEGKGSTFYISLPYEPYEEEWWE"
     gene            4677..5993
                     /gene="yycH"
                     /locus_tag="ACG8LA_002382"
     CDS             4677..5993
                     /gene="yycH"
                     /locus_tag="ACG8LA_002382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system activity regulator YycH"
                     /protein_id="HFQ0204660.1"
                     /translation="MRISEKVVRIGLILMVALSIYFSYAIWLSPAGKSSINVDETNTQ
                     MIESQSNRKTSEVFLPLHVTWHHSGMIQETNSENLVYRLQLIIDKARFGKLSEVVSGD
                     KSQFEQVKNLNSGFELAYNAPFLLREYKEAFDLDLDVSNLAKESENMYFTRIQFDQGN
                     KKIRFLNYSNHLVYEANISLNWTDINKELTAKDTKWTEMTTEPSTIDTQYATKHSIKL
                     KKYSYILSQQPYTLFRNAFFQKPDSVKNNDESNELIFYGGNETMSIHSETQVVDFRGE
                     LPEKKENASVFSESFPYISKLGSSLGNLRYFDRSDNTIDYRIFVEGFPVFGTDSRGQI
                     GVEVGGETNGSVQVNIQTSLNTIQVPIPSDEEVELASTNEIIQQLKAKGADSNKIGSV
                     IVGYTWQNVKETNRVVDLLPEWYVKYKDNWYSANDLLEKLPGLEAN"
     gene            5994..6863
                     /locus_tag="ACG8LA_002383"
     CDS             5994..6863
                     /locus_tag="ACG8LA_002383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system regulatory protein YycI"
                     /protein_id="HFQ0204661.1"
                     /translation="MDFKKIEWIFFVAFLGLNVFLFSSYHDAVYQENNVIRSNQTESI
                     QQRLASDDITYTGKISSENKQGYYLSAEQTNLSTSLANYRKAGKSGLLASGVFLDGDV
                     LTKSLSSSDAEKNVIDPDKISSSLEDFLSNKDNILFGNDYVYTKNFSHLEEEPLEIQA
                     SQEYEGIPFNDDTAKIVLSLEKNDNDYSITKYMQTHLSDIEQLREKTELYTEEEAINT
                     LYINNKIPRGSKILWRQLAYSCILKVREKNVYVPVWHVAIETSDKVVQIESVNAFSNT
                     IVTNNTVPKVEDQ"
     gene            6918..7727
                     /locus_tag="ACG8LA_002384"
     CDS             6918..7727
                     /locus_tag="ACG8LA_002384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HFQ0204662.1"
                     /translation="MAEEKPAFKISILASGSSGNSLYIESEKKRLLVDAGLSGKKITS
                     LMAQIDRTPDQLDGILVTHEHRDHIHGVGVLARKYHLDVFANQQTWEAMEPLIGNVPV
                     EQKHLFEMGKVRTFGDIDIESFGVSHDAAAPQFYRFHKENRSFVMLTDTGYCSDYMRG
                     VIENADGYLMESNHDLEMLRMGPYPWNLKQRILGDRGHLSNEDGALVMTDVIGNRTKR
                     IYLGHLSKENNMKELAHLTMENVLKEKDFGVGHDFEIYDTDPDEATELFSI"
     gene            complement(7830..8459)
                     /locus_tag="ACG8LA_002385"
     CDS             complement(7830..8459)
                     /locus_tag="ACG8LA_002385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HFQ0204663.1"
                     /translation="MKIALIGATGHAGSFILDEALSRDLDVTAIVRHPEKLPSDVPFI
                     QKDLFELTTTDLASFDVVVDAFNAPKGKEEMHQTSLSHLIEMLEGTDTRLIVVGGASS
                     LFLDTEKTTRMIDQVPKNAPFYPTAFNMYEGLLKLKQSKNLHWTYISPASLFDPHGKR
                     TGTYLLSDDYLQRNAAGDSTISMADYAIALVDEILDEKHEKQHISVVSR"
     gene            8629..9921
                     /locus_tag="ACG8LA_002386"
     CDS             8629..9921
                     /locus_tag="ACG8LA_002386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFQ0204664.1"
                     /translation="MKEWLDRAFLPMITSVVNLRPLTALRNGMTYTIPIIIVGSLFFL
                     FAHFPVDYIAQWIDKTGFSMYFTQVYQATFDVIAFWIVFAIAYAYAKEEDIDRLPVGI
                     TALSAYLLLIQPLNTQIDTVWTGAEGILGAVTTGLIIGWGYARLVRLAKGWKQREKIP
                     ENVWQSFTSLIPIIVIVTFTLIGSAVFQQLFRMTVVQGVWTYVQLPIQSFIDTLFGVL
                     LLGFFVPFLWLFGLHGSAMVNGLVSPVLQANSLANAEILASGQELTVANGGHIVTQQF
                     LDQFMTVTGAGLTLGAVFFMTVFAKSKKYRELGNLALLPAFFNINESIIFSTPIVMNP
                     MMAVPFIFAPVVSGLITYSALYFGFVPLFTAVQVPWTTPPILSGFLVGGVPAAILQGI
                     VLSISFFIYFPFLKKIDSANCKKERQTKNDGAAEKMND"
     gene            complement(9997..10659)
                     /locus_tag="ACG8LA_002387"
     CDS             complement(9997..10659)
                     /locus_tag="ACG8LA_002387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="HFQ0204665.1"
                     /translation="MSLKKYSFLSIFCYGLIFISPLILASIGLVKSTSELITATAVMY
                     ILGAVVLAIFYFKQREPLAIESAVKKASAPKIVIYGLVGIFVALILQSIAVMLESVLF
                     GKATPSENTQNIIQMIMEAPAFILATTVAGPIMEEFVFRRSILGIISRYSNFWVGAVI
                     SSLLFAFAHNDGHLLIYFFLGFFFSLEYKATGRIWTSMITHVGMNTLVVLVQLAVQKG
                     LV"
     gene            10884..11168
                     /gene="groES"
                     /locus_tag="ACG8LA_002388"
     CDS             10884..11168
                     /gene="groES"
                     /locus_tag="ACG8LA_002388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HFQ0204666.1"
                     /translation="MLKPLGDRVIIEVAKEEEKTVGGIVLASAAKEKPQTGTVVAVGE
                     GRLLENGEKVPAAVKAGDQVMFEKYAGTEVKYEGKEYLIVAGKDIMAIVE"
     gene            11219..12844
                     /gene="groL"
                     /locus_tag="ACG8LA_002389"
     CDS             11219..12844
                     /gene="groL"
                     /locus_tag="ACG8LA_002389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736685.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0140662 - ATP-dependent protein folding
                     chaperone [Evidence IEA];
                     GO_process: GO:0042026 - protein refolding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HFQ0204667.1"
                     /translation="MAKELKFAEDARAAMLRGVDKLADTVKVTLGPKGRNVVLEKSYG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     LKNVTAGANPLGIRRGIELATKAAVEELHNISTVVDSKEAIAQVAAVSSGSDKVGHLI
                     ADAMEKVGNDGVITIEESKGIETELDVVEGMQFDRGYLSQYMVTDNDKMEAVLENPYI
                     LITDKKISNIQDILPLLEQILQQSRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITDDLGLELKDVTIENLGNASKVVVDKDNTTIVEGS
                     GEKEAIEARVQLIKNQIAETTSDFDREKLQERLAKLAGGVAVVKVGAATETELKELKL
                     RIEDALNATRAAVEEGMVSGGGTALVNVISKVSAVEAEGDVATGIKIVVRALEEPIRQ
                     IAENAGYEGSVIVDKLKNVELGTGFNAATGEWVNMVEAGIVDPTKVTRSALQNAASVS
                     ALLLTTEAVVADKPEPAAPAAPAMDPSMMGGMM"
BASE COUNT         4370 a         2265 c         2833 g         3679 t
ORIGIN      
        1 taaaaaaaga acagcgtaaa tgttttcgaa atgctttcgc accaacattt acctgttccg
       61 tgggtttggc acccaatggg ccgtgagggg ctcgaacccg cgacccgctg attaagagtc
      121 agctgctcta ccaactgagc taacggcccg tacaaaaagt acttaataat agtagcacta
      181 agaattttaa aatgcaagac tacatttaaa gaaaatcaga aaaatcttta cttccttata
      241 ggaaatcatt catagattat tcacatttgc tcgctattat ataagcatac caacaaacaa
      301 agttcttgca agagaacaaa ccctaacact tttttcattt tttactcctt tcccgccgtc
      361 tccccggcgg gtctcctgtt cttaacgata aaagacaaga aggcttagcc ttcttgtttt
      421 ttgttttcat ggaatcccgc taatcaaatc acctagttaa agcaactaga ttgaatgttt
      481 atcataagtc tgatatcatg tttatgaaat gaaaaaagga gcggttatga tggaaaaaat
      541 gcgtcagcaa ttaatggagt gggggaagga actagaaaca ttccgtctgc ctcactggga
      601 agaactccct gacttagaac tttatatgga ccaagtcaga acgttagttg atcgttatct
      661 ttcacctgtg atacaaggag aaaagcatcc attgcttacc tcttctatgg taaacaatta
      721 cgttaaacta ggtttgatac cagcaccagt taaaaaaaga tataacaaag aacacgtagc
      781 atttttactt gcaatcacta cgttgaaaca agtattgact attcctgaaa tcaaagaagg
      841 gatattgttc caaggaaaaa cagtaggaat tcgtgaagcc tataatctat tttgcgatga
      901 acaagaagca gctgtgtgga tggtcagcca attagcacaa ggtaaatctc atccgcaaaa
      961 attcgaccag gcaacccctg tagaatatat tgctgtaaga gcggcaactt tatcgtttgc
     1021 aatgaaactt cttgcggaaa aaacgattgt tctagaaacc gaatatttaa aagaggagaa
     1081 aacaaatgaa aaacaataaa atcgcaattt tagtagattc aggtacggat gtgccagaag
     1141 aattgataaa aaaatacgag atgtatatga tcccattgaa aattatttat aaagatcagg
     1201 tatatacaga taaaattgac attacctctg aagagatcta tcaacgtttg ccagaggaaa
     1261 tccctggtac atctttgccg gatggtgagt cgatcacaga aatctttgag caaatcaaaa
     1321 aagacggtta tgaaaaggta cttgcggtaa caatttccag tggattgagc gggacatata
     1381 atgtggttcg tttaattgca caacagcaag aagaattgga agcatatgta ctagatacga
     1441 aaaatattgg tattggtgca ggtttttctg cgatccaagc agcaaaatgg ctggaagaag
     1501 gagtagaatg ggatcaactg atcagtaatc tgaatgagtt agtcgaaaga acaaaagttt
     1561 tctttaatgt tgcgacattg gaatatcttc aaaaaggtgg acggatcggt ttagttgctt
     1621 ctattgtagg aaccgcttta aagcttaacc caatcatctc atgtaatgaa gaagggattt
     1681 attacacagt aggaaaagct aggggacgta aaaaaagttt ggataaaacg gttgcttacg
     1741 tcaaagaaaa aatcggtaat gcaaaggtct tcaacttagc tgttgcccat ggggatgcga
     1801 aagaagaagc aattgaaatg gaagcgagac ttaaaagaga gttcccacaa gcaaaccaaa
     1861 tctactttgg ccagatttct ccggcattag tagtccacac tggtccggga ttattgggtg
     1921 tcggtgtaca agttttagaa ggataaatca aaaaaaggaa acactgaggt gaaaatcagt
     1981 gttttccttt tttattgaag ttagaacaaa aaataataaa gtattttgca ctttcatttt
     2041 aattttctct tttgttttat aggcaaagat gaaacaaaag cagaaatacg gtataatgag
     2101 aaggtatgac aataatatat aagaggtggc tctttatgaa aaaagtttta gttgtcgatg
     2161 atgagaagcc gatttcggat atcgtcaaat tcaatttagc caaagaaggc tatgatgttt
     2221 atactgcata tgatggggaa gaagccttgg aaaaagttgc tgaggtagaa cctgatttga
     2281 ttttacttga tttgatgcta cctaaaatgg acggcttaga agttgctcgt gaggtacgca
     2341 aaacttatga tatgccgatc attatggtaa cagccaaaga ttctgaaatt gataaagtcc
     2401 taggcttaga gttaggcgcc gatgattacg tgaccaagcc attttccaac cgagaattag
     2461 ttgcacgtgt caaagcaaat cttcgtcgcg gtgccacggc tgcgaaggaa ccagaagagg
     2521 cagcacctgc ggaattgacg attggtgatt tgacgatcca tccagaagct tacatggtga
     2581 cgaaacgagg agaaacaatc gagttaacac atcgtgaatt cgaactactc ttttacttgg
     2641 cgaagcacct tggacaagtg atgacaagag aacatttatt acaaacggtt tggggttatg
     2701 attattttgg agatgtacga acagtggatg taactgtacg tcgtttgcgt gaaaagatcg
     2761 aagataatcc aagccatcca aattatttag tgacacgtcg tggtgtcggt tactatttgc
     2821 gtaacccaga acaggagtaa ttggatgaaa agaaaagtcc gcttttttcg atcagtcaat
     2881 tttaagatcg ctattacctt tattctgatt ttattgatct cgatcgaaat tattggtgcc
     2941 tactttatac gtggtttaga acgttccacg atcaatacat ttattaaaga tatgaatcaa
     3001 acggtggaat cattagcaac aacaatcagc ccggaattga atcgaaaaga taatgcagat
     3061 gatgaagagg taaatgcgaa tatcaaaaga tttattgaaa acagtgcgac tagcgatatc
     3121 atcgaaatac gggtcgttga cgaaaaaggg atcatccgag gaacaaccga tgtcaatgaa
     3181 caaagcgctg tgggaaagaa aaatgattat gttgatatca atgatttcac gactaaacgt
     3241 tatgttgctt tagataacga cgataaacgg gtgaatatca atgttcaacc gatcctgtcc
     3301 ccgaccggcg atgccgttat cggggctctt tacgtcaaaa gtaatatcga acaaaaatat
     3361 tcggaaatca ataacacagc agtcattttc tttactgcct cactaattgc ggcatttatt
     3421 tcaatgatcg tatctgtttt agttgctcgt tcgattacac agccgatcgg tgaaatgaga
     3481 gaacaagcca ttcgaatcgc tagaggagac tacagtcgga aagtcaaagt gcatggacaa
     3541 gatgaacttg gacagctggc tgataccttc aatcagttag ctgaacgtat tgaagaagct
     3601 caagatacaa tggaagctga acgcaatcgt ttggatagcg tgctatccca tatgacagac
     3661 ggcgtcattg cgacagatcg caggggtaaa gtcattacga tcaatgatat ggctgtttcc
     3721 ttgctagata tcaaaaacga ggaagcaatc ggacaatcga ttttgacact tttagatatc
     3781 gaagaagaat atacgttgcg gaaattatta gaagatccaa acgaaatggt acttgaccgt
     3841 tcaaccagta cattggaaag tgatcagatg atcttgcgag tagacttttc tatgatccgt
     3901 cgcgaatcag gttttatcag cggattagta gctgtcttgc atgatgtgac agaacaagaa
     3961 aaaacagaac gggaacgtcg tgaattcgtc tctaatgttt cccatgaact tcgtacaccg
     4021 ttgacaagta tgcgtagtta tatcgaagca ttgagcgaag gtgcgtggaa agacgaggaa
     4081 gtagcaccaa attttttgaa ggtaacgcta gatgaaacag accgaatgat tcgaatgatc
     4141 aatgacctct taaatctatc tcgcatggat acaggtaata cccagcttca attagaatat
     4201 gtcaatttca acgagttagt gaattttgtt cttgaccggt ttgatatgat ggtgggaaat
     4261 caggaaaaaa attataagat ccgtcgtgaa tttacgcaaa gagatctttg ggtcgaagta
     4321 gatacagata aaatcatcca agtagtcgat aatatcatga ataacgcgat caagtattca
     4381 ccagatgggg gaacgattac ttgtcgctta ttagaaacgc ataataacgt ggttttaagt
     4441 atcaccgatc aaggattggg gattcctaaa aaagatctga accgagtgtt cgagcggttc
     4501 tatcgagtag ataaagcacg tgcaagagca caaggtggga caggacttgg attagctatt
     4561 tctagagaag tgattaaggc gcatcgaggc gctatttggg cagagagcaa ggaaggaaaa
     4621 gggtcgactt tttatatctc gctgccatat gaaccttatg aggaggaatg gtgggaatga
     4681 gaatctctga aaaagtcgtt cgtataggac tcattttgat ggttgcgtta agcatatact
     4741 tctcttatgc aatctggctg agcccagcag gaaaaagttc aatcaacgta gatgagacaa
     4801 acactcaaat gatcgagtct caaagcaatc gaaaaacttc cgaagtcttt cttccgcttc
     4861 atgttacatg gcaccattcg ggaatgatcc aagaaaccaa cagtgaaaat ctcgtgtacc
     4921 gattgcaatt gatcatcgat aaagcaagat ttggaaagct ttctgaagta gtttcaggag
     4981 acaaatcaca gtttgaacag gtgaaaaatc tgaactctgg ttttgagttg gcctataatg
     5041 cgcctttttt gctaagagaa tacaaggaag catttgattt agatttagat gtgtcgaact
     5101 tggcaaaaga aagcgaaaat atgtatttta ctagaataca attcgatcaa ggaaataaaa
     5161 aaatccgatt tttgaattat tcgaaccatc tcgtatatga agcaaatatt tcgttgaatt
     5221 ggacagatat caataaagaa ttaacagcaa aagacacaaa atggacagaa atgacaacag
     5281 aaccatcgac gatcgacacg caatatgcta cgaaacattc gatcaaactg aaaaagtata
     5341 gttatatcct gtcacagcaa ccctatacac tttttagaaa tgcttttttc cagaaaccag
     5401 atagcgtgaa aaataatgat gaaagcaatg aattgatttt ttacggtggg aatgaaacaa
     5461 tgtctatcca ttcggaaacg caagtagttg attttcgtgg agagctgcca gagaaaaaag
     5521 aaaatgctag tgtattttct gaaagtttcc cctatattag caaattaggc agttctttag
     5581 ggaacctcag atattttgac cgcagtgaca atacgatcga ttatcggata ttcgtggaag
     5641 gcttcccggt ttttgggaca gacagcagag gacagattgg tgtggaagtt ggcggtgaaa
     5701 cgaatggttc tgtgcaagtg aatatccaaa ccagtttgaa tacgattcaa gtgccgatac
     5761 cttcagacga agaagtagaa cttgcaagta cgaatgaaat catccagcag ttaaaagcta
     5821 agggagcaga tagcaacaag attggttcag tgatcgttgg ctatacatgg caaaatgtca
     5881 aagaaacgaa tcgtgtcgtt gatctcttac ctgaatggta tgtgaaatat aaagataact
     5941 ggtattcagc taacgacctt ctggaaaaat tacctggatt ggaggcgaat taattggatt
     6001 tcaaaaaaat cgaatggata tttttcgtcg cttttttagg gttgaatgtg tttttattca
     6061 gcagttatca tgacgcggta taccaagaaa acaatgtcat tcgctctaat cagactgaat
     6121 caatccaaca acgtctggct agcgacgata tcacttacac ggggaagatt tcgtctgaga
     6181 acaagcaagg ctattatctt agcgcggagc agaccaatct tagcacttca ttagcgaatt
     6241 atcgcaaggc tggtaaaagc ggcttgctgg caagtggtgt gtttttagac ggtgatgttt
     6301 tgacgaaatc tttatccagt tcagatgctg aaaagaacgt gatcgatcca gataaaatta
     6361 gtagttcctt ggaagatttt ttatctaaca aagacaatat tttattcggt aatgattatg
     6421 tgtacacgaa aaacttttct catttagaag aagaaccact agaaatccaa gcaagccaag
     6481 agtatgaagg catcccattc aatgatgata cagcaaaaat cgttctttct ttagaaaaaa
     6541 acgataatga ttatagcatc acgaaataca tgcagacgca tttatctgat atcgagcagc
     6601 tgcgcgaaaa gacggaactg tatacggaag aggaagcaat caatacattg tacatcaata
     6661 acaaaatacc aagaggatca aaaattttat ggcgtcagct agcttattcc tgtattctga
     6721 aagtccggga aaaaaatgtg tatgttcctg tttggcatgt agcgatcgaa acaagcgata
     6781 aagtggtcca aattgagagt gtcaacgctt tcagcaatac gatcgtgaca aacaatactg
     6841 taccaaaagt ggaagatcaa taaaaaagcg agtataatga aaaaagttta caaagtaaga
     6901 agggaagtag gagtcaaatg gctgaagaaa aaccagcttt taaaatcagt atcctagcaa
     6961 gtggaagttc gggtaattca ctttatatcg aaagtgaaaa aaaacggctt ttggtcgatg
     7021 caggacttag cggtaaaaaa atcacttcct tgatggctca aattgatcgg acaccggacc
     7081 aattagatgg aatacttgtg acgcatgaac atcgagatca tatacatggc gtgggtgtct
     7141 tggctcgtaa gtatcatttg gatgtttttg ccaatcagca gacttgggaa gcgatggaac
     7201 cactgattgg aaatgtacca gtggaacaaa aacatctatt tgagatgggg aaagtcagaa
     7261 cattcggcga tatcgatatt gagagtttcg gcgtctccca tgacgcagcg gctccgcaat
     7321 tttatcgttt ccataaagaa aatcggtcat tcgtcatgtt gacggacacc ggatattgca
     7381 gtgattatat gcgaggtgtc attgaaaatg ccgatggtta tttgatggaa agtaatcatg
     7441 atcttgagat gttacgcatg ggaccttatc cgtggaattt aaaacagcgt attttaggag
     7501 atagaggaca tctttccaac gaagacggtg cacttgtcat gactgatgtg atcggtaatc
     7561 ggaccaaacg aatctatctt ggccatctta gcaaggaaaa caatatgaaa gaacttgctc
     7621 atttaacaat ggaaaatgtt ttgaaagaaa aagattttgg cgttggacat gattttgaaa
     7681 tctatgatac agatccagat gaagcaactg agctattttc gatttaaaca gttcaatcaa
     7741 taaaaatata aaaagcagaa gataaaatca atcagggttg gttttatctt ctatttttat
     7801 ttttttagca tattaaaaaa ataaccgtat tatcgactga ctacactgat gtgctgcttt
     7861 tcatgtttct catccagtat ctcatctact aatgcaatcg cgtaatctgc catgctgatc
     7921 gtactgtcgc cagcagcgtt tctttgtaaa taatcatcac ttaacaaata agtacctgta
     7981 cgtttgccat gtggatcaaa taaagaagct ggactgatat aagtccaatg tagattttta
     8041 gattgtttca attttaacaa tccttcgtac atattgaaag ctgttggata gaagggtgca
     8101 tttttaggta cttggtcaat catacgagtc gtcttttctg tatctaagaa taacgaagag
     8161 gcacccccaa cgacaattaa gcgtgtatcg gttccttcaa gcatctcaat caaatgggac
     8221 aaagaagttt gatgcatttc ttcttttcct ttgggagcgt tgaaagcatc aacgacaaca
     8281 tcaaaagatg caagatcagt agttgtcaac tcaaataaat ccttttgtat aaacggaaca
     8341 tctgatggca atttttctgg atgacgcacg attgccgtca cgtctaaatc tctggacaat
     8401 gcttcgtcta aaataaatga acctgcatgg ccagtagctc caatgagtgc aattttcata
     8461 aaaaacctcc ttttttattc ctgtccattg taagcagttg ctgaatattc gtcaaagaat
     8521 ccgatttttg aaaagctcag tgcgcattcc tttcatggtt cgtgatcatt gggtatagtt
     8581 aaattaagaa aactgattga taaaaataga agttgaagga gataagaaat gaaagagtgg
     8641 ttagatcgtg cctttttacc aatgataaca tctgttgtga atcttagacc cttaactgct
     8701 ttgcgtaatg gaatgactta cacgatccca ataattattg ttggctcgct gtttttctta
     8761 tttgctcatt ttcctgtgga ttacatcgct cagtggatag acaaaacagg attttctatg
     8821 tattttacac aagtatacca ggctacattt gatgtgatag ccttttggat cgtttttgcc
     8881 attgcatacg cttatgcaaa agaagaagac atcgatcgct taccagtcgg cataacagcc
     8941 ttgtctgctt atctactgct tattcagcca ctaaatactc agatagatac tgtctggaca
     9001 ggtgctgaag ggatactagg agcagttaca actgggctca tcatcggatg gggctatgca
     9061 cgtttagtaa gacttgcgaa agggtggaag caaagagaga agatacctga aaatgtttgg
     9121 cagtctttta cttcattgat tccaatcatt gttatagtca cttttacgct tatcggttca
     9181 gcggtttttc aacagttgtt cagaatgact gttgttcaag gagtatggac atatgtccag
     9241 cttcccattc aatcgttcat agacacgttg tttggtgtgc ttttattagg tttttttgtt
     9301 ccgtttttat ggttatttgg tcttcatgga tctgcgatgg tcaatgggtt ggttagtccc
     9361 gtcttgcaag cgaattcatt agcgaatgca gaaatcttag cctcaggaca agagttgacg
     9421 gtggcaaatg gcggacatat cgttactcag caatttctcg atcagttcat gacggttacg
     9481 ggtgctggat tgacgttagg ggctgtattt tttatgacgg tttttgcgaa atcgaagaaa
     9541 tacagagaat taggaaatct tgctctttta ccagcctttt tcaacatcaa tgaatcaatt
     9601 attttttcca caccgatcgt gatgaacccg atgatggctg ttccttttat tttcgcaccg
     9661 gtcgtttcag gattgattac ctattccgct ttatattttg gattcgttcc tttatttaca
     9721 gcagtccaag tcccttggac aacaccgccg atcctctcgg gtttcttagt aggcggagtg
     9781 cctgcagcga ttttacaagg tatcgtgttg tcaattagtt ttttcattta tttcccattt
     9841 ttgaaaaaaa tagattctgc aaactgcaaa aaggaaagac agacaaaaaa tgatggagca
     9901 gcagaaaaga tgaacgacta aaaaacaaaa atactcctgt cgctttagat tgggaaaatc
     9961 accaatctag gatgacagga gtatttatag tcatgtttat actagccctt tttggacagc
    10021 taattgaaca agaacaacta atgtgttcat tcctacgtgt gtgatcatcg atgtccagat
    10081 ccgaccagtt gctttgtact ctaggctgaa gaagaaacct aggaaaaagt agattagcag
    10141 atgaccatca ttatgagcaa acgcaaacag caaagagctg atcactgctc cgacccaaaa
    10201 atttgaatat cgactgatga tccccagtat actgcggcgg aatacgaact cttccatgat
    10261 gggtccagca acagttgtcg ccaaaataaa agcgggtgct tccatgatca tctggatgat
    10321 attttgtgta ttctcggaag gggttgcttt gccaaacaat acagattcta acatgacagc
    10381 gatgctttgc agaatcaatg cgacaaagat tccaaccaat ccataaataa caatctttgg
    10441 agcagaagct ttttttaccg ctgattcgat cgctaagggt tcacgttgct taaaataaaa
    10501 aatagctagg acaacggcgc ctagtatata catgactgca gttgctgtga tcaattcaga
    10561 cgtagatttt acaagtccta tcgaagctag gatcaagggt gagataaaaa ttagaccata
    10621 gcaaaaaatg ctgaggaagc tatatttttt taaagacatg taattcctcc ttttaaggga
    10681 taacaagcat gcaaggcaag cttatatcga ttgatttcaa ttatatcata atttcaataa
    10741 gcagctgtca gaataaaatt tcttttcttt gatttaaaag cttgcaaaaa agagggagaa
    10801 tgagtattat taaaaatgta ggttagcact cgaaggttaa gagtgctaac agattaaaaa
    10861 aagagttatc ggagggattt atcgtgttaa aaccattagg tgatcgcgtc attatcgaag
    10921 tcgcaaaaga agaagaaaaa actgtcggag gaatcgtttt agcttctgct gctaaagaga
    10981 aaccccaaac tgggacagtt gttgcagtcg gtgaaggccg tttgttagaa aacggtgaaa
    11041 aagttcctgc cgctgtaaaa gcaggcgacc aagttatgtt cgaaaaatac gccggtacag
    11101 aagtaaaata cgaaggaaaa gaatatctga tcgtcgcagg aaaagatatc atggcgattg
    11161 ttgagtaaat ttggaagata aaaaaataat caaaaataat caatgaggtg aatcaatcat
    11221 ggcaaaagaa ttgaaatttg cagaagacgc acgcgcagct atgttacgcg gggtagataa
    11281 attagcagat acagtgaaag taacattagg acctaaaggc cgaaatgtcg tactagaaaa
    11341 atcttacggc tctccattga tcacaaatga tggtgtgacg atcgcaaaag aaatcgaatt
    11401 agaagatcat tttgaaaaca tgggtgcaaa acttgtatca gaagtagcat caaaaacaaa
    11461 tgatattgca ggagacggta caacgacagc aactgttctg acacaagcaa tcgttcgcga
    11521 aggtttaaaa aacgtaactg caggtgctaa tcctctaggc attcgtcgcg ggatcgaatt
    11581 ggcaacaaaa gcagcagtcg aagaattgca taatatctca actgttgttg attcaaaaga
    11641 agccattgca caagtagcag ctgtttcttc gggttctgat aaagttggac atttgattgc
    11701 tgatgcaatg gaaaaagttg gaaacgacgg tgtcatcaca atcgaagaat caaaagggat
    11761 cgaaacagaa ctagatgttg tagaaggtat gcagtttgat cgtggttact tatcacaata
    11821 tatggtaaca gataacgaca aaatggaagc tgttctagaa aacccatata tcttgatcac
    11881 agacaaaaaa atctctaaca tccaagatat tctgccattg ttagaacaaa tcttgcaaca
    11941 atcacgtcca ttgttgatta ttgctgacga tgtagatggt gaagcattgc caactcttgt
    12001 attgaacaaa atccgtggaa cattcaacgt agtagctgta aaagctcctg gtttcggcga
    12061 tcgtcgtaaa gcaatgcttg aagatatcgc tattttgaca ggtggtacag taattactga
    12121 cgatctaggt ttagaattga aagatgtaac aatcgaaaac ttaggaaatg cttctaaagt
    12181 tgttgtagat aaagacaata caacgatcgt agaaggttct ggagaaaaag aagcaatcga
    12241 agctcgtgtg caattgatca aaaaccaaat tgctgaaaca acttctgatt ttgaccgcga
    12301 aaaattacaa gaacgcttag ctaaattagc aggtggtgta gctgttgtta aagttggtgc
    12361 agctactgaa acagaattga aagaattaaa attacgcatt gaagatgcat tgaatgctac
    12421 acgtgccgca gtagaagaag gaatggtctc aggtggtggt acagctctag tgaacgttat
    12481 cagcaaagtt tctgctgtag aagcagaagg agacgtggca acaggtatca agatcgttgt
    12541 tcgtgcttta gaagaaccaa ttcgtcaaat cgctgaaaac gctggttatg aaggatcagt
    12601 gattgttgat aaattgaaga acgtggaact aggcactggt ttcaatgctg ctactggaga
    12661 atgggtaaac atggttgaag caggtatcgt agacccaact aaagtaacac gttctgcctt
    12721 gcaaaatgcc gcttccgttt ctgccttgtt attaacgaca gaagcagtcg ttgcagataa
    12781 accagaacca gcagcgccag cagctcctgc aatggatcca tcaatgatgg gcggtatgat
    12841 gtaagaaaaa gcaacttgct tatctacaac tgatcattag tgaaagacag ataaaaagag
    12901 gctggaacag aagcgtttaa ctccaagaaa taagaagaaa ttcacggaaa ttgcttttca
    12961 aatttttgtg aatttcagct tatttccgaa ggagttgctt ctgcttccgc tgtttatacg
    13021 tgtttagagc gtgagacaaa agtgttcttt acttttgtcc cacgctcttt tttgtgtgta
    13081 attataatga aaatagttat ttttaatagt tataatattt tatctattaa aagtaaatat
    13141 ccattca
//
LOCUS       DAZKKZ010000073        12733 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.075, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000073 DAZKKZ010000000
VERSION     DAZKKZ010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12733)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12733)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12733
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.075"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(85..264)
                     /gene="rpmF"
                     /locus_tag="ACG8LA_002390"
     CDS             complement(85..264)
                     /gene="rpmF"
                     /locus_tag="ACG8LA_002390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HFQ0204668.1"
                     /translation="MAVPARRTSKAKKAKRRTHYKLTIKGLNECPNCGEMKKSHHVCA
                     NCGYYDGKDVMSKEA"
     gene            complement(322..891)
                     /locus_tag="ACG8LA_002391"
     CDS             complement(322..891)
                     /locus_tag="ACG8LA_002391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HFQ0204669.1"
                     /translation="MKWSLLELRKYQETPLTFHETLDLKAALMKRDNLILDVAPVEVE
                     GLVSVDKKGYIVHYTVQTTLTVPSTRSLEPVELPMDFSVDEVFMTEEQFQSRDEQMSA
                     DEILLIEGPLLNLAESIEDNILLAIPMRVLTKEEEAATELPKGNDWEVVSEEEYQRRK
                     MEEAENKIDPRLAKLSELFDSKSKDDDNK"
     gene            1077..1979
                     /locus_tag="ACG8LA_002392"
     CDS             1077..1979
                     /locus_tag="ACG8LA_002392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR substrate-binding domain-containing
                     protein"
                     /protein_id="HFQ0204670.1"
                     /translation="MNTKDIEYYVQIVKQKNFTKVANYFRVSQPTITYALQRLEKEFD
                     TVLITRDRSHHELIVTPSGKQLFLHAQTILQEISTARAEITQLQKKKLRFGMPPIIGN
                     EYFPKLSSYFIKHELMNQIEITDGGSRDLYGMIRQGRIDLAVLGSTQPIVDQYLETEL
                     LLDKRFMIVVPPTHPLSKQDTVSFKDIADEQFVLLNEHYVHPAAFTKLSKQTHTHPKV
                     VYQSNDLTILKSMVRENVGIGFLAEIAVHPEDHLVCLPLSDEVQPRFLISLAKRTQQI
                     VTPLQEQVVQVIHEFVTAQKNSSS"
     gene            complement(2014..3798)
                     /gene="pyk"
                     /locus_tag="ACG8LA_002393"
     CDS             complement(2014..3798)
                     /gene="pyk"
                     /locus_tag="ACG8LA_002393"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004743 - pyruvate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0030955 - potassium ion binding [Evidence
                     IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HFQ0204671.1"
                     /translation="MKKTKIVSTLGPASNSVEIISQLIESGANVFRFNFSHGDHEEQL
                     SRMTMVREAVKKTGKDVGILLDTKGAEIRTTVQGTTEADFGRAGYIKFEVGDQTRISM
                     DPEHVGSKEKIAVTYPGLFDDVHVGGHILFDDGLIDMQIIEKDEANRELVVEVKNAGM
                     LGSRKGVNAPGVSISLPGITPKDADDIRFGLDNDIDFIAASFVRKAQDVLDIREILEE
                     KDMTHVQIFPKIESQEGIDNIDEIIKVSDGVMIARGDMGVEIPAELVPMVQKRIIKKC
                     NAAGIPVITATQMLESMQENPRPTRAEASDVANAVFDGTDATMLSGESANGDYPVEAV
                     STMARIDQEAENALSELGTFQLNEFDKTDVTETIGLSVARAAKNLGVKTIVAATESGY
                     TAKMISKYRPDADILAVTFDERTKRGLMLNWGVYPTVAEKPSTTDEMFELAAKKAVEL
                     GFASEGDLILITAGVPVGERGTTNVMKIQMIGSKLLEAQGVGQKSVVANAVIASSAEE
                     AVKKAKDGMVLVVPSTDKEYMPAIEKAAAVIVEEGGLTSHAAVVGIAQDIPVIVGAKG
                     ATTTITEGELITVDSRRGIVYRGETTAI"
     gene            complement(3872..4834)
                     /gene="pfkA"
                     /locus_tag="ACG8LA_002394"
     CDS             complement(3872..4834)
                     /gene="pfkA"
                     /locus_tag="ACG8LA_002394"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010746303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006002 - fructose 6-phosphate metabolic
                     process [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HFQ0204672.1"
                     /translation="MKRIGILTSGGDAPGMNAAVRAVVRKGIYEGLEVYGINYGFAGL
                     VAGDIRRLDVADVGDKIQRGGTFLYSARYPEFATEEGQLKGIEQLKKFGIEGLVVIGG
                     DGSYHGAMALTKRGFPAVGIPGTIDNDIPGTDFTIGFDTAINTVLESIDRIRDTATSH
                     VRTFVIEVMGRNAGDIALWSGVAGGADEIIIPEHDFDMASVAKKIQEGRDRGKKHCLI
                     ILAEGVMGGNEFAEKLSEFGDYHTRVSILGHVVRGGAPSARDRVLASKFGAYAVELLQ
                     EGKGGLCVGIHDNEIVASDIIDTLENNKHKPDLSLYDLNNSLSF"
     gene            complement(5002..8316)
                     /gene="dnaE"
                     /locus_tag="ACG8LA_002395"
     CDS             complement(5002..8316)
                     /gene="dnaE"
                     /locus_tag="ACG8LA_002395"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HFQ0204673.1"
                     /translation="MFFPQLYTITSYSLLQSTIRIREYVQEAKKQGYTSLAITDKDVL
                     YGAPEFYRICVEEGVQPIIGLHLSYTYEEKNYGLLAYAKDEIGYQQLMKLSSRKMIQE
                     KLELAEMTETDHLAFVVPANHSVSEAFNKEDNFFGHWQFLLENVFTRNFYIGLTENTP
                     DQLPEWYQYVIKENYSLCALHPIASLQQEELFALEVMKHIKEGSQIPLENLSASLPLT
                     ANVYLLSEQEMIKRFEKAGLSQAVIGAQRLAESISFEFQFHQKLLPHYPVPNGKQAGE
                     YLRELCYSQVERRITDYTKEYQERLDYELSVIHQMGFDDYFLIVWDVMAFAHRNKIVT
                     GAGRGSAAGSLVAYVLEITDVDPLEYDLLFERFLNPERFTMPDIDLDIPDNRREEVLN
                     YVREKYGQYHMAQIATFGTMAAKMVLRDAARVFGLSQSEANRWSKAIPNQLKITLTQA
                     YKTSHQLVELVQASEKNQLLFKTAVILEGLPRHVSTHAAGVVISDKNLLELVPLQRGS
                     DEAFLTQYTMNEVEAIGLLKMDFLGLRNLSIIDFTLKAVKRVEGYEIRLKEIPLNDAK
                     TLLLFQRGETSGVFQFESAGIRNVLRRLDPENIEDIAAVNALYRPGPMQNIDTFIARK
                     KGKEAIRYPDDSLIPILKNTYGVIVYQEQIMQIASTMAGFTLGQSDILRRAVSKKKKD
                     VLDEEKSHFVSGALQQGYSEKTAATVYEYIEKFANYGFNRSHAFAYSFVGFQMAYLKA
                     HHPGAFFTSLMNSVRHNTSKLKEYIAEARKNKLKLSSPSINQSNSSFELVNKEEIRFG
                     LTAIKGIRRDFVEDILNERKQNGPFQSVDQFLIRIDKRWLKLELLQSLTAVGVFDELS
                     PNRKQLMLDLEGKIQNIVYSGGSLDLLGIMALKEEEVADYTLEERLKLEEEYLGIYLS
                     GHPAEGFDRLRLAKQVQLITDIVPNQPVNLLVMIKEVREIRTKKGELMAFVEGTDSSG
                     EISVTVFPTLYRKYRNLFAVDRVIFVQGRSEISKYNQELQLIGESFADPNQLEAQYPS
                     QTCYLRITEEREDPEIMKQLQVIFQKHPGYIPVVMYHEKTQRKVVLSDAYWVDDSKSI
                     KGQLIYLLGEDNVVFK"
     gene            8547..8732
                     /locus_tag="ACG8LA_002396"
     CDS             8547..8732
                     /locus_tag="ACG8LA_002396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjzD family protein"
                     /protein_id="HFQ0204674.1"
                     /translation="MRYIVTLFWAVVLGQVVGYIGAALTSGTYDFTLTTIISFIAGVI
                     ILLIGAVAPRKETSAHS"
     gene            complement(8794..9990)
                     /locus_tag="ACG8LA_002397"
     CDS             complement(8794..9990)
                     /locus_tag="ACG8LA_002397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HFQ0204675.1"
                     /translation="MEINWRKNLVIAWIGCFFTGASISLVMPFIPVYVEQLGTPKDQI
                     ELFSGLAISVTAFASAVVAPIWGNLADRKGRKLMMIRAAAGMTLTMGSLAFVPNAYWL
                     LIMRFWNGILSGYIPNATAMIASQAPREKSGWALGTLSTGAIAGNLIGPSMGGALAQW
                     FGMENVFLITGALLMITTVLTIFLVKEDFHPIEKKDLISTKEIFSKMDHLSILIGLFI
                     TTLILQIGITTISPILTLYIRELSGSTENILFVSGLIVSIAGVSAVFSSPKLGKLGDK
                     IGNQKVLIGGLILSFCCYLPMAFVTTPLQLGILRFILGFSTGALMPSVNTLISKITPQ
                     EGVSRIYSYNQMFSNFGQVLGPMLGSTVAHAYNYSAVFIVTSLFVLSNILLSLFNFRK
                     VLRSRL"
     gene            complement(10160..11596)
                     /locus_tag="ACG8LA_002398"
     CDS             complement(10160..11596)
                     /locus_tag="ACG8LA_002398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HFQ0204676.1"
                     /translation="MEKFFGLKKNNTNVSTEIMAGVTTFFAMSYILFVNPTILSASGM
                     PFQAVFLATIIASIIGTLVMGLFANVPYAQAPGMGLNAFFTFTVVFGLGYSWQQALAM
                     VFICGLINIFITVTNIRKMIIRAIPESLQHAIGGGIGIFVAYVGIKNAGFLSFSADQS
                     AISSSVVEGGKATNVTINGGIVPALANFDNAPILLAVIGLVLTAILVVKNVRGAILIG
                     IVATTVLGIFMGVVDLSSIDWQTNSLGNSFKELGTTFGAAFGSEGMQSLFSDSSKIPQ
                     VLMTIIAFSLSDTFDTIGTFIGTGRRTGIFSKEDEIALEDGRGFKTKMDKALFADAIA
                     TSVGAIFGTSNTTTYVESAAGIGAGGRTGLTSVVVAVLFALSSLFSPLIAIVPNQATA
                     PALILVGVMMMASFADIKWLDMEEALPAFFASIFMGLCYSISYGIAAGFIFYTIVKVI
                     KGKYNQVSVALWIVDILFIINFIILATI"
     gene            11889..12698
                     /locus_tag="ACG8LA_002399"
     CDS             11889..12698
                     /locus_tag="ACG8LA_002399"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFQ0204677.1"
                     /translation="MNKKLIAIDLDGTTLNQDSMITSKTKETLKKAINAGHHVSIATG
                     RPFRMSHQFYQQLELTTPMVNFNGALVHIPNQHWDGERETLINREIAFEILSQKKQLN
                     LDFIAAENRDTFFIDSFDFFDEKIFASSRPGEKNLLSPKNLTTNPTSLLVRTDKRFAG
                     AVSAELTRQFGSYVDVRTWGGPTAILEIVSKGIQKAKGVQEIANYLSIDQKDVIAFGD
                     EHNDLELLDYAGWGVAMANGTDQLKGIANDVTPLSNQEDGLAVYLEKLLKL"
BASE COUNT         3801 a         2673 c         2250 g         4009 t
ORIGIN      
        1 attttttatt taccgactac aaaaaaataa acctcaaggc tccatggtta gccttgaggt
       61 tttacatttt ctaattaaaa tgtattaagc ttcttttgac attacgtcct taccatcata
      121 gtaaccacaa tttgcacata cgtgatggct ttttttcatt tcaccacagt ttggacattc
      181 gtttaaccct ttgattgtca atttgtagtg tgtacgacgt tttgcttttt tagcttttga
      241 tgttcttcta gctggtactg ccattttgct acacctcctt gtaaagtctt gtatctaaat
      301 tagacacaat atattccaat cttacttgtt atcgtcgtct tttgatttag aatcaaaaag
      361 ttcagatagt tttgcaagac gaggatcaat tttattctcg gcttcttcca tttttctgcg
      421 ctggtattct tcttcggaaa caacttccca atcattgcct tttggaagtt ctgttgctgc
      481 ttcctcttct tttgtcaata cccgcattgg aatcgccaat aagatgttgt cttcaatcga
      541 ctctgctaaa ttcaataatg gaccttcaat tagcaaaatc tcatctgcag acatttgttc
      601 atctctactt tggaattgtt cttctgtcat gaatacttcg tctacagaaa aatccatggg
      661 cagttcaaca ggttctagtg aacgtgttga aggaactgtc aaagtcgtct gcacagtgta
      721 atgaacgata tagcctttct tatcaactga gaccaaacct tcgacttcca ctggcgcaac
      781 atcaagtatt aaattgtctc gcttcatgag agcggctttc aagtcgagcg tctcatgaaa
      841 agttaacggt gtctcctggt attttctcaa ttccaataaa gaccatttca tttttcatca
      901 ctcctaagca acaaaagcaa ttatacaggg caaaaagcat gttgtcaatg aaattttctt
      961 gacaccttgc agttcataaa aaaacagaaa aatctttatt agaaagcctc tgtttgctat
     1021 catcctcaga atcatttaca ataatcatta ttccattaaa ggagcggatg atcttcatga
     1081 acacgaaaga tatcgaatac tatgtccaaa tcgtcaaaca aaaaaatttt acgaaagtgg
     1141 ctaattattt ccgtgtgagc caacctacta ttacatatgc attacaacgt cttgaaaaag
     1201 agtttgacac cgtacttatt acaagagatc gatcgcatca cgaattaatc gtcacgcctt
     1261 ctggaaagca gctgtttctc catgcacaaa ccattctcca agagatttct actgcaagag
     1321 ctgaaatcac tcagttgcaa aagaaaaagc ttcgttttgg catgcctcct attatcggca
     1381 atgaatactt tcctaaactg tcaagttact ttatcaagca tgaattgatg aatcaaattg
     1441 agattaccga tggaggctct cgggacttat acgggatgat ccgacaaggg aggatcgatt
     1501 tagctgtatt aggctcaaca cagccaatcg tggatcaata tttagaaaca gagttacttt
     1561 tggacaaacg tttcatgatc gtcgtgccac ctacacatcc tctttccaag caggatactg
     1621 tctctttcaa agatatagca gatgaacagt ttgtactatt gaacgaacat tatgtccacc
     1681 ccgcagcatt cactaagctt tctaaacaaa cacatactca tccaaaagtt gtttatcaaa
     1741 gcaatgactt gacgatttta aagagtatgg tccgagaaaa tgtgggtatc ggttttttgg
     1801 cagagattgc tgtccatcct gaagatcatt tagtttgcct ccctctttca gatgaagttc
     1861 agcctcgctt cttgatttca ttggcaaaac gaacacagca gatcgtcacg cctcttcaag
     1921 aacaagtagt ccaagttatc catgaattcg ttacagcaca aaaaaacagc tcttcgtaaa
     1981 agaagagctg tttttatttt ttattaagct aaattagata gctgttgttt cgccacggta
     2041 aacgatgccg cgacgtgaat caacggtaat caattcacct tctgtaattg ttgttgttgc
     2101 gcctttagca ccaacgatta caggaatatc ttgtgcaatt cctacaactg cagcgtgaga
     2161 agtcaatccg ccttcttcaa cgataacagc agctgctttt tcgattgcag gcatatattc
     2221 tttgtcagtt gatggtacaa ctagaaccat tccgtctttt gcttttttta cagcttcttc
     2281 agcagatgaa gcaataactg catttgcaac gacagatttt tgtccaacgc cttgagcttc
     2341 taataattta gaaccaatca tttgaatttt catcacgtta gttgttccgc gttcaccaac
     2401 tggtacacca gcagtgatca agattaaatc gccttctgat gcgaaaccta attcaacagc
     2461 ttttttagct gctagttcaa acatttcatc agttgttgat ggtttttcag caactgttgg
     2521 gtaaacgccc cagtttaaca tcaaaccacg ttttgtgcgt tcgtcaaaag taacagccaa
     2581 gatatctgca tctggacgat attttgaaat catttttgca gtgtatcctg attcagttgc
     2641 agcaacgatt gttttcacgc ctagattttt tgcagcacga gctacagata aaccgattgt
     2701 ttcagttaca tctgttttat cgaattcgtt caattggaat gtacctaatt ctgataatgc
     2761 attttcagct tcttggtcga tacgtgccat tgttgaaaca gcttcaactg ggtagtcccc
     2821 gtttgcagat tcaccagata gcattgttgc atctgtgcca tcaaatacag cgttagcaac
     2881 gtcagaagct tccgcacgtg ttggacgtgg gttttcttgc attgattcta acatttgtgt
     2941 agcagtgata actgggatac cagcagcatt acattttttg ataatgcgtt tttgaaccat
     3001 tggtactagt tcagctggga tttcaacacc catatctccg cgggcaatca taacaccgtc
     3061 agaaactttg atgatttcgt caatgttgtc gataccttct tgagattcga ttttagggaa
     3121 gatttgaaca tgagtcatgt ctttttcttc taagatttcg cggatatcta gaacgtcttg
     3181 tgctttacgt acaaaacttg cagcgataaa gtcgatatcg ttgtctaaac caaaacgaat
     3241 atcgtcagca tcttttggag taatacctgg caaactaata gaaacgcctg gtgcatttac
     3301 ccctttacgt gatcctagca tacctgcatt tttaacttct acgactaatt cacggtttgc
     3361 ttcgtctttt tcaatgattt gcatatcgat caaaccatca tcaaataaaa tgtgtccgcc
     3421 aacgtgaaca tcgtcaaata atcctgggta agtaaccgcg attttttctt ttgaacctac
     3481 atgttcagga tccatagaga tgcgtgtttg atctcctact tcaaatttga tgtatcctgc
     3541 acgaccaaaa tcagcttctg ttgtgccttg aacagttgta cggatttcag ctccttttgt
     3601 atctaaaaga ataccgacat cttttcctgt ctttttaact gcttcacgga ccatagtcat
     3661 acgtgataat tgttcttcat ggtcaccatg agaaaaatta aagcggaaga catttgcccc
     3721 agattcaatc aattgagaaa taatttctac tgagttactt gctggtccta atgtactaac
     3781 gattttggtt tttttcattt aaaaaactct cccattcaat tttgtttatt taaagctgta
     3841 cacagcttaa atagcttggt ttctttcact cttaaaatga aagtgaatta tttagatcat
     3901 atagtgataa gtctggttta tgtttgttgt tttcaagtgt atcaatgatg tcagacgcaa
     3961 cgatttcgtt gtcatggata ccgacacata atccaccttt tccttcttga agcaattcga
     4021 cagcgtaagc accgaattta cttgccaaca cgcggtcgcg tgcgcttggt gctccaccac
     4081 ggacaacgtg tcccaagata gatacacgtg tatgatagtc accaaattct gaaagtttct
     4141 cagcgaattc atttccgccc attacacctt cagccaagat gatcaagcaa tgtttcttcc
     4201 cgcgatcgcg gccttcttgg atttttttag caactgaagc catatcaaaa tcatgttctg
     4261 ggatgatgat ttcatccgct ccgccagcca cacctgacca taaagcgatg tctcctgcat
     4321 tgcgtcccat tacttcgata acgaatgtac gaacatgaga agtcgctgtg tcacgaatac
     4381 ggtcaattga ttctagtact gtattgattg ctgtatcaaa accgattgtg aaatcagtcc
     4441 caggaatatc attatcgatt gttccaggaa tacctactgc tgggaaaccg cgttttgtca
     4501 aagccattgc gccatgataa gagccgtctc ctccgataac cactagacct tcgattccga
     4561 attttttcaa ttgttcgatt ccttttaatt gaccttcttc agttgcaaat tctggataac
     4621 gtgcagaata caagaatgta ccaccacgtt ggatcttgtc acctacatct gccacatcaa
     4681 gacgacgaat atctccagca actaaaccgg caaaaccata attgatcccg tatacttcca
     4741 gtccttcgta aataccttta cgaacaacgg cacgaacagc tgcattcatt ccaggtgcgt
     4801 ctccgccact ggtcaaaatt ccgatgcgtt tcataataaa cattcacctc attaaaatac
     4861 tttatcctaa gtatgactta ggtttacaac catttttgcg ttaaccacga ctaacattct
     4921 aacattattt ttctcacttg tcttgattta cggataaaaa aatgaaaaaa aatgaaagca
     4981 agtagtattt tttaccgtaa gttatttgaa aaccacatta tcttcgccaa gcagataaat
     5041 aagttgcccc tttatactct tgctgtcatc cacccaataa gcatctgaca gaactacttt
     5101 tcgttgcgtt ttttcgtgat acataactac tggtatatat cctgggtgtt tctgaaaaat
     5161 cacttgtaat tgtttcatta tctcgggatc ttcccgttct tctgtaatac gcaaatagca
     5221 agtttgtgaa ggatactggg cttctaactg gttaggatca gcaaagcttt ctccaattag
     5281 ttgcagttcc tgattatatt tgctgatttc gctccgccct tgaacaaaga tcactcgatc
     5341 aacggcaaac aaattacgat atttacgata aagagttgga aaaactgtga cagaaatttc
     5401 tccactactg tcggttcctt caacaaaggc catcagttct cctttttttg tccgaatttc
     5461 tctaacttcc ttgatcatca ctaataaatt gactggttga ttagggacga tatctgtaat
     5521 cagctgaact tgtttagcta aacgaagacg atcaaaccct tctgcaggat gacctgacaa
     5581 ataaatacct aagtactcct cttccagctt caagcgttct tctagtgtat agtcagcgac
     5641 ttcttcttct tttaatgcca tgattcccag caagtcaaga cttccaccac tgtaaacgat
     5701 attttggatt tttccttcga gatcaagcat caattgtttc ctgttaggag ataattcatc
     5761 aaaaactcct actgctgtca gtgattgcag taactctaat ttcagccaac gcttatcgat
     5821 ccgtatgagg aattgatcca ctgactggaa cgggccattt tgttttcttt cgtttaatat
     5881 atcttctaca aaatcacgcc gaataccttt tatcgctgtc agtccgaatc tgatttcttc
     5941 cttattgacc aactcaaaac tggaattact ttgattaatg gacggcgagg aaagtttgag
     6001 tttattttta cgtgcttctg caatatattc tttcaatttt gatgtgttat gccgaacaga
     6061 attcatcagg ctggtaaaga aagcacctgg atgatgggct tttagatacg ccatttggaa
     6121 tcccacgaat gaataagcaa atgcatgtga ccgattgaat ccatagtttg caaatttttc
     6181 gatatattca tatacggtcg ctgctgtttt ttccgaatat ccctgttgta atgctcctga
     6241 tacaaaatgc gacttttctt catctaatac gtcttttttc tttttactca ctgcccgtcg
     6301 cagaatatct gactgcccta atgtaaatcc agccatagtc gaggcgatct gcatgatttg
     6361 ttcctgatag acgatcactc catatgtgtt tttcaaaatc gggatcagtg aatcatctgg
     6421 gtagcgaatg gcttcttttc ctttcttcct ggcaatgaag gtatctatat tttgcatagg
     6481 gcctggtcga tacaatgcat tgactgcggc aatatcttcg atgttttctg gatctaatct
     6541 tcgtaaaacg ttccggatac cagcagattc aaattgaaat actcctgagg tttcgcctcg
     6601 ttgaaacaag agcagcgttt ttgcatcatt tagcgggatc tcttttaatc ggatctcata
     6661 cccttctact cgcttaacag ctttcaaagt aaaatcaata atcgataagt tgcgtagtcc
     6721 taaaaagtcc attttcaaaa gaccgattgc ttctacctca ttcatcgtat actgggtcag
     6781 aaaagcttca tcagaaccgc gttggagcgg aactagttca agtagattct tatcgctgat
     6841 aactacacct gctgcgtgag tcgaaacatg tcttggcaat ccttctaaaa tcactgcagt
     6901 tttgaataaa agttggtttt tttcgcttgc ctgaactaat tctactaatt gatgcgaagt
     6961 tttataagct tgggtcaatg tgattttcaa ttgattgggt attgcttttg accagcggtt
     7021 tgcttcactt tgcgataaac caaacactct agctgcatct ctaagaacca tttttgctgc
     7081 cattgtgcca aatgttgcga tttgtgccat atgatattgt ccatactttt ctcgaacata
     7141 attcaatact tcttcacgtc gattgtcagg aatatccaaa tcgatatctg gcatcgtaaa
     7201 gcgttcgggg tttaaaaagc gttcgaacag caaatcatat tctaatggat ccacatctgt
     7261 gatttctaac acataggcta ctaatgaacc cgcagcagaa ccacgacctg caccggtaac
     7321 gattttgttt ctatgagcaa aagccattac atcccatacg atcaagaaat aatcatcgaa
     7381 tcccatttga tggatgacag ataactcgta gtccaaacgt tcttggtatt cctttgtata
     7441 gtcagtgatt cggcgttcca cttgcgaata gcataactct cttaaatatt ctccagcttg
     7501 ttttccatta ggaactggat aatgcggaag taatttctga tggaactgga attcaaatga
     7561 aatcgattca gctaaacgct gggcgcctat tacagcttgg gaaagacccg ctttttcgaa
     7621 tcgtttgatc atttcttgtt ctgaaagaag atagacattt gctgttagtg gtaaagatgc
     7681 agataaattt tctaaaggta tttggcttcc ctctttgata tgtttcatca cttcaagtgc
     7741 aaaaagttct tcttgttgta aactagcgat gggatgtaat gcacaaagcg aataattttc
     7801 ttttatcaca tactgatacc attcaggcaa ttgatcaggc gtgttttctg tcaagccgat
     7861 ataaaaattt ctagtaaaaa cattttcaag taaaaactgc caatgaccga aaaagttatc
     7921 ctctttattg aaagcctcag aaacagaatg atttgccgga acaacaaacg ctagatggtc
     7981 ggtttctgtc atttctgcaa gttccaattt ttcttggatc atttttcggc tggaaagttt
     8041 catcagctgc tgataaccta tttcatcttt tgcgtacgca agcaagccat aatttttttc
     8101 ttcataagta taactaagat gtaatccaat gattggctgt actccttctt ctacacaaat
     8161 acgatagaat tcaggtgcac cgtataagac atctttatcc gttatggcta atgaagtgta
     8221 gccttgtttt tttgcttctt gtacatattc tcgaatacgt atcgtacttt gtaaaagaga
     8281 ataagaagta attgtataaa gttgtgggaa aaacatcttg cattccgcct tttttttcgt
     8341 taaaattcac tagcgttaaa aggtttgatc cttttacttt cattaagata gcaggcgctg
     8401 aagttgatta ttccacttca tttgcttgct tgtaatctgt aggaatgagt tctttcgcaa
     8461 gaactcaaat tttattgaga tttggtctcg tttctttaca ttcaaagaaa atctggtaaa
     8521 attaagatag aaaagaggtg ttctttatgc gatatatcgt tacattattc tgggctgtcg
     8581 ttctaggtca agtagtcggt tatattggtg ctgcattaac aagcggaaca tatgatttta
     8641 ctttgacaac aatcatttca ttcattgcgg gtgtcattat ccttttgatt ggtgcagttg
     8701 cgccaagaaa agaaacctct gcccattcgt aaaaaaacag ccaagagctt gagatttctc
     8761 aagctctttt ttattttcta ctcctcacca ccattataat ctgctgcgaa gaactttacg
     8821 aaagttgaat aaagaaagaa gaatatttga cagaacaaac aaacttgtca caataaaaac
     8881 agcactgtaa ttataagcat gcgcgactgt cgatcctagc atgggaccta aaacttgtcc
     8941 aaagttgcta aacatctgat tgtagctata gattcggctg actccttctt gaggcgtaat
     9001 cttactgatc agtgtattga cagaaggcat caaagcgcca gttgaaaagc ctaaaataaa
     9061 gcgaagtata cctaattgga gcggtgtagt gacgaatgcc ataggtaaat aacagcaaaa
     9121 tgataaaatg agtcctccaa ttagaacttt ttgattccca atcttatccc ctagttttcc
     9181 tagtttcggt gaagaaaaga cagcggaaac accagctatc gaaacaatca agccgctgac
     9241 aaaaaggata ttttctgtac ttccgctcaa ttcacgaata tataaggtca aaatagggct
     9301 gatcgtagtg attcctatct gtaaaatcaa ggtcgtaatg aagagaccga tcaaaataga
     9361 gagatgatcc atttttgaaa aaatttcttt ggtgcttatc agatcttttt tctcgattgg
     9421 atggaaatct tctttgacta agaaaatggt caataccgtt gtgatcatca acaaagcccc
     9481 tgtgatcaag aatacatttt ccataccaaa ccactgagcc agtgcaccgc ccattgaagg
     9541 tccgatcaga tttccagcaa tcgctccggt agacaatgtt cctaacgccc atccgctctt
     9601 ttctctaggt gcctgtgaag caatcatcgc tgtggcattt ggaatatatc cagacaaaat
     9661 cccattccaa aaccgcatga tcaaaagcca atacgcgttt ggtacaaaag ccaaagatcc
     9721 cattgttaat gtcatccctg ctgctgcacg gatcatcatg agttttcggc cttttcgatc
     9781 agctagattt ccccagattg gtgcaaccac ggcagatgca aaagcagtca cagagattgc
     9841 tagtcccgaa aacaattcga tttgatcttt tggtgttcct agttgctcaa cataaactgg
     9901 tatgaatggc ataactaaac taatacttgc accagtgaaa aaacagccaa tccacgcaat
     9961 cactaaattt tttctccaat taatctccat ctatcatccc tctttcgtct cttttatcat
    10021 acctattttc gaataaacaa gcaacgatct cgccagtaaa aagagaaaaa tcccgcaaag
    10081 gtcattttat atgtaacgtt ctttttatgt aaaacaaaaa gagatcagaa caaatactgt
    10141 tccaatccct tctctttagt taaattgttg ctagaatgat gaagttgata atgaataaaa
    10201 tatcaacgat ccacaaagca acagaaactt gattgtattt tcctttgatt actttcacaa
    10261 ttgtatagaa aataaatcct gctgcaatcc cataggaaat gctatagcac aatcccataa
    10321 agatcgatgc aaagaaggcc ggtaaagctt cttccatatc tagccatttg atgtctgcaa
    10381 aagaagccat catcattact ccaactaaaa tcaatgctgg cgcagttgct tgatttggta
    10441 caatggcgat cagtggagag aataaactac ttaatgcgaa tagcactgcc actactactg
    10501 aagtcaaacc agtacgtcca ccggccccga tcccagctgc agattcgaca taagttgttg
    10561 tattcgatgt accaaagata gcccccacag aagtagcgat cgcatcggca aatagtgctt
    10621 tatccatttt tgttttgaac ccacgaccat cttccaacgc gatctcgtct tcttttgaga
    10681 aaatacctgt gcggcgtcct gtaccgataa atgttccgat cgtatcgaaa gtatcagata
    10741 aactgaatgc gatgatcgtc atcaatactt gaggaatctt ggaagaatca ctgaataaag
    10801 attgcatgcc ttcagaacca aatgctgcac cgaaagttgt tcctaattct ttaaatgaat
    10861 tacctaacga attcgtttgc caatcaatgg aacttaaatc aacaacaccc ataaaaatac
    10921 caaggactgt ggtcgctacg ataccgataa gaatagcccc acggacattt tttacaacta
    10981 aaatggctgt cagtaccaaa ccaatcacag ccaataagat aggagcgttg tcaaagttgg
    11041 ctaacgcagg gacgattcca ccatttatcg taacatttgt cgcttttccg ccttcaacga
    11101 cagagctcga aatagctgac tggtctgctg aaaaagataa gaatcctgca tttttgattc
    11161 cgacatacgc aacgaaaata ccgatcccgc caccaatcgc atgttgaaga ctttcgggaa
    11221 tcgcccgaat aatcattttt cgaatatttg tgacagtaat aaaaatattg attaatccgc
    11281 aaataaacac cattgccaag gcttgttgcc aagaataacc aagcccaaaa acgaccgtaa
    11341 aagtgaaaaa tgcgttcaat cccataccag gtgcctgagc atatggtaca tttgcgaaca
    11401 atcccattac cagcgtacca ataatcgatg caatgattgt cgctagaaat actgcttgga
    11461 agggcatacc tgatgctgac aaaatcgtcg gatttacgaa taagatataa ctcatggcaa
    11521 agaatgtcgt tactcccgcc attatttcag ttgatacatt tgtattgttt ttctttaaac
    11581 cgaaaaactt ttccataaaa agttccactc cctgaatttt tttctgatgg aaaactataa
    11641 taataaaaaa taagtaaaat agggcaaatc catcgaacaa tttcaaatta tatagacgtt
    11701 tcattcgctt ttcaacgttt ttttaacaaa aaaagcgaaa ataatactta acgttcgtgt
    11761 ttagcttatg tttagctatt tatatagcca taactgtagt ttttgttagg aatagctgat
    11821 tgctcttgtt aattacctaa aatatgctag actaaaacaa atgctagttg aggaaggaag
    11881 gacccttatt gaataaaaaa ttaattgcca tcgatctgga cggaactacc ctcaatcaag
    11941 attcgatgat tacatctaaa acaaaagaga ctctaaaaaa agcaatcaat gccggtcatc
    12001 atgtcagtat tgctacagga cgcccattcc gaatgagcca tcagttttac caacaattag
    12061 aattaacaac accgatggtt aattttaacg gcgcattagt acacatccct aatcagcact
    12121 gggatggtga aagagaaacg ttgatcaatc gtgaaatcgc ttttgaaatc ttatcgcaaa
    12181 aaaagcagct aaatttagat tttatcgctg ctgaaaatcg tgatactttt tttattgaca
    12241 gttttgattt ctttgatgaa aaaatttttg cttcttctcg tccaggagag aagaatttgc
    12301 tttctcctaa aaatttgacg acaaatccta catctttgct tgtccgaaca gacaaacgtt
    12361 ttgcaggagc tgtatctgct gaattaacac gtcaatttgg cagttatgtc gatgttcgga
    12421 catggggtgg acctactgcc atcttagaga ttgtttcaaa aggaatccaa aaagcaaaag
    12481 gcgtgcaaga gattgctaac tacctgtcta tcgatcaaaa agacgtcatt gcctttggtg
    12541 acgagcataa tgatttggaa ttgttggatt atgcaggttg gggagtagct atggctaacg
    12601 gtactgacca actcaaaggc attgcaaatg atgtcactcc tttgagcaat caggaagacg
    12661 gtttagctgt ttatctggaa aaactactta aactataata gagaattaga ttccacaaaa
    12721 aagaggttgt gac
//
LOCUS       DAZKKZ010000074        12728 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.076, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000074 DAZKKZ010000000
VERSION     DAZKKZ010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12728)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12728)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12728
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.076"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            87..530
                     /locus_tag="ACG8LA_002400"
     CDS             87..530
                     /locus_tag="ACG8LA_002400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HFQ0204678.1"
                     /translation="MDKRQLLIEEYLDLANEIIHRNKPEMEKEFAGFTLNELEVIEHI
                     GKIPDPNVTKLANASYMTRGAISKLTKKLIARGIINTYQSEENKKEIYFQLTPIGQKI
                     RNRHEQLHQKWVQRDATVFENMSKEEFDTVFRFIGRYREFIRSSK"
     gene            complement(536..1720)
                     /locus_tag="ACG8LA_002401"
     CDS             complement(536..1720)
                     /locus_tag="ACG8LA_002401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance MFS efflux pump"
                     /protein_id="HFQ0204679.1"
                     /translation="MYSFTNKHSKVFGYVSVLFTGLGFTIVSPVLPFLTLPYSHSIHQ
                     QAFYITLLMSVYALAAFLSAPILGSLSDHFGRHPILIISLLGSSIGYLLFGLGNSIWM
                     LFLGRIIEGLTAGEISTLYAYFADITEPNERTKVFGWMGALVGIGTTLGPIIGGLLAE
                     LGNSVPIFIGALFTFLNAVYGYTFMLESLPIKKRSVDLSFSHVRPFHQLQQLFKISSV
                     IPLLTAGFAVWLAAGSLQSIFSQFSIDAFQWKAGLVGLSFSLIGILDTVSQLFIMPRL
                     LKKFSEQQITRIGMFSEILAYLFITLSGILLLPILFLFGIICYGFGDSIFTPVFNGQL
                     SNSVSDNQQGLVMGGTQSIQSLSRVIGPLIAGQLYAAAPFLPTVFGFLLMIFAYYHYN
                     KK"
     gene            1988..2686
                     /locus_tag="ACG8LA_002402"
     CDS             1988..2686
                     /locus_tag="ACG8LA_002402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HFQ0204680.1"
                     /translation="MLNLENYLSAGQTVISNLLLKNYHRIGLQSEEFLFVLQLHMAQL
                     EGDTFPDLQMIAMDMGIKQDQIFQILDRLVTNGFIKIETTIVNGKKADRYNLYPIYDL
                     LGEYLKTQEKKYEEKTQEKEIQSVYQLFEQEFGRPLSSIEFQRIGQWLEEDHYQPEIL
                     KLALREAVLNQAYSFNYVDRILLSWERKNLRTKQQVEEDQKRRKQQLLQREVEQSAQQ
                     EELPKVSLKNWLEE"
     gene            2693..3370
                     /gene="nth"
                     /locus_tag="ACG8LA_002403"
     CDS             2693..3370
                     /gene="nth"
                     /locus_tag="ACG8LA_002403"
                     /EC_number="4.2.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140078 - class I DNA-(apurinic or
                     apyrimidinic site) endonuclease activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HFQ0204681.1"
                     /translation="MLSKQKTMEALETMYGMFPEAHGELKHNNPFELLIAVILSAQAT
                     DVSVNKATPDLFASFPTPDALAEASIDEIILKIKTIGLYRNKAKNIKACAQQLIERFD
                     GQVPTSREELMSLPGVGRKTANVVLGDAFGIPAIAVDTHVERVSKRLRICKLDATVME
                     VEETLMRKVPQELWVKTHHTLIFFGRYHCTARNPKCEVCPLLSICQDGKNRMRLKEKA
                     LKKKPRL"
     gene            complement(3496..4029)
                     /locus_tag="ACG8LA_002404"
     CDS             complement(3496..4029)
                     /locus_tag="ACG8LA_002404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204682.1"
                     /translation="MVLNNFLKEGFILSYLIVCLIIIICLHHLFLSKTIPRYSKNKKA
                     EKFCLLLNKFTLIAPILAFIIFSVLLSTTLKGKFMERSSHAMILTFLWLLFTRIYIFL
                     MSLKPPKSISLCLVINGIFLLSLIIFITPLDRYVTYLYNPLEYWTYFIGILEGIIFYI
                     GYFPNKNNNFYFYRNKL"
     gene            complement(4326..6707)
                     /locus_tag="ACG8LA_002405"
     CDS             complement(4326..6707)
                     /locus_tag="ACG8LA_002405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HFQ0204683.1"
                     /translation="MANEQTRSSRRQKQPTPKKSVKKNSGKGSGKSSGTHKKGLFIKI
                     LLGILSFFCILFLAGVGLFWYYAKDAPELTDKKLDATVSSKLYTQDGELFEDLGAEKR
                     EKISANELPKTLEDAIVSVEDRRFYKHIGVDPIRIIGSALSNFTSGGLQGGSTLTQQL
                     IKLSFFSTSAEDQTLKRKAQEAWMAVRLEQKKSKQEILTYYVNKVYMSNGLYGMETAS
                     EMYFGKKLSELSLPQTALLAGMPQAPSAYDPYVYPDQAKKRRDTVLYTMLQNEKISQT
                     EYDQAVNVPVTDGLQELTQSDDNTKIVDNYVKEVINEVQEKTDKNVYTDGLEIYTNLD
                     LDAQKKLYDIVNTDQYVSYPDDEMQVASTLIDTNTGKVKAQIGGRHIAEDVTLGNNLA
                     VNTSRDFGSTMKPVTDYGPAFEYLKYSTGKTITDAPYNYEGTSTPVGNWDNQYMGTIT
                     LRQALYLSRNVPAVKLFNEVGSDKVASFLKNLGIEYSTIHQSNAISSNTEEQDGTKYG
                     ASSLKMAAAYAAFANGGTYYKPQYVNKIVFQDGTEETYEPDGKTAMSPETAYMITDIL
                     KDTITEGTGTNAQIAGLYQAGKTGTSNYTDDEYAKLGISSGVYPDILFAGYTPNYSIS
                     VWTGYNKKMTPVTSESSHVASDVYRELMQYVSANVTNTDWEMPSGLIRVGGELYYKDQ
                     YTARSNAITPSTTIPSSSYVQTPGSSTTETTTQSSSSTSQSESTAESSKESTTAETSE
                     PASSTTVPSSSSEESSTPSSSAPPASSSEPATSGADAANDHTPSSSTSASGNR"
     gene            complement(6697..7344)
                     /gene="recU"
                     /locus_tag="ACG8LA_002406"
     CDS             complement(6697..7344)
                     /gene="recU"
                     /locus_tag="ACG8LA_002406"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HFQ0204684.1"
                     /translation="MVLRYPNGQPYYKNASPVEKIQEKRNQITEFGNRGMRFEEAINE
                     SNKYYLSRGLAVIHKKPTPIQIVKVDYPKRSAAVIKEAYFTQASTTDYNGVYRGFYLD
                     FEAKETKNKTSFPFKNFHAHQIEHMKACLEQNGVCFVLLWFSSLKRCFYLNSVHLIAY
                     WDAQKEKGRKSLPLSLIEELGIEIKTGISPRIPYLDAVDFYLSTLSIEGESKNGK"
     gene            7408..7947
                     /locus_tag="ACG8LA_002407"
     CDS             7408..7947
                     /locus_tag="ACG8LA_002407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HFQ0204685.1"
                     /translation="MDKSKVIYVSGYRSFELGVFKENDPKIQVVKNVLKKELHQLAEE
                     GLEWVLVSGNLGVELWAVQIVAELKEEYPELSLGILYPFSDFGNNWNEGNQEKKQLAE
                     QLADYVEAVSHQPYQSPSQLKNHTRFILEHTVGCLLIYDEEFPGKTKYFFEDAQNYQA
                     DHPYEIRLISMDDLQNFSE"
     gene            8037..8456
                     /gene="gpsB"
                     /locus_tag="ACG8LA_002408"
     CDS             8037..8456
                     /gene="gpsB"
                     /locus_tag="ACG8LA_002408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HFQ0204686.1"
                     /translation="MANLVYSPKDILQQEFKTKMRGYDPVEVDEFLDNIIKDYETYSK
                     ELLALQEENDRLSAKVAQLSKTQGAAQTRVQQTEAPKSAAVTNFDILKRLSNLEREVF
                     GKKLDQQASAVKPAQPNPNNYTNADTSLDDNEKTRQF"
     gene            8478..8845
                     /gene="rnpB"
                     /locus_tag="ACG8LA_002409"
     ncRNA           8478..8845
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="ACG8LA_002409"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            9054..10220
                     /locus_tag="ACG8LA_002410"
     CDS             9054..10220
                     /locus_tag="ACG8LA_002410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HFQ0204687.1"
                     /translation="MEKNRKFNLVATAASGLEALVGKELRDLGIECQVENGRARFEGT
                     METIATANLWLRTADRVKIVVGEFDAYTFDELFENVKALPWEDFLPLDAAFPVAGKSI
                     KSKLYSTPDCQAITKKAIVERLRTYYHRPASVPLTETGAHFQLEVALLKDHVMVTLDT
                     TGPSLFKRGYRLEKGGAPLKENMAAALIMLTNWRKDRPFYDPVCGSGTLCIEAALIGH
                     NIAPGFNREFACESWDWFSQEIMENVRSAAEEKADYDIELDITGSDINGRMIEIAKAN
                     AEEIGLGSSITFKQQAVKDFKTDKEYGVIVANPPYGERLGEEETVRKLYKEMGDVFRP
                     LKTWSKYILTSDLAFEEFYGQKATKKRKLYNGALRTDLFQYWGTRPPRKKEKDE"
     gene            10266..11762
                     /locus_tag="ACG8LA_002411"
     CDS             10266..11762
                     /locus_tag="ACG8LA_002411"
                     /EC_number="3.4.17.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004181 - metallocarboxypeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxypeptidase M32"
                     /protein_id="HFQ0204688.1"
                     /translation="MKEKEFLQEVKEINLLQQALGILDWDTQTGMPEKASAYRSEVDS
                     YLYSIYFSKKIGPKIKEAIRYFSEHPEELSEVGTAVFAKVKEEYDLEHRVPEDLMRKY
                     TAAVSSAHGQWQKARETQQFSDFQHALNQNIELTKQLIPYWRKDEKTNYDVLLNQYEP
                     GMTVEILDKVFDQLKEGILSIRRTLQEKGTEPETDFLNRRMTKKQQKRFVVKVIEQLG
                     YDFSRGRLDDTVHPFMTGINPNDARITTRWNETDFKMAVFGVIHEAGHGMYEQDIDDK
                     YAYTPVYEGTSMGIHESQSLFNEIIIGSSRSFWKKQYPFFQECAEGTFDDIPFDKFYR
                     SLNHTKSSLVRIEADSLTYPLHIIIRYEIEKMIFNEGVDVAELPEIWNQKYEEYLGIR
                     PTNDVEGILQDVHWSGASFGYFPSYALGYMYAAQLLHSLQQEIDVENVLASDDYSPIK
                     NWMSEHIHQYGASRKPNQLIMDATHEPLNPQYLIDYMKDLYFNVYQVK"
     gene            11843..12526
                     /locus_tag="ACG8LA_002412"
     CDS             11843..12526
                     /locus_tag="ACG8LA_002412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HFQ0204689.1"
                     /translation="MDKLQVIADYSMDQLAHDQTGHGSDHTKRVVKLAEKILETEPQA
                     DRFVTLAAAYLHDTIDDKVVKNENEAKQQLRVFLRSLPIVEEQISMIFSIIENMSFSK
                     NLSEAAELSLEGKIVQDADRIEALGAIGILRTAYFGGGHGHPIFDPELYPQTFKDKEN
                     YRKGTTVINHFYEKLFLLSDKMNTDYGYEEAKRRETFMREFLEEFFLEWSIDDENFTP
                     DNWIKNNKK"
     gene            12535..>12728
                     /locus_tag="ACG8LA_002413"
     CDS             12535..>12728
                     /locus_tag="ACG8LA_002413"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204690.1"
                     /translation="MTEVVSSKIFRIIFRKSYFWNTVYQEVVSLPFSSESQGTISKNS
                     FSCLMNIVTCDSELAGEHRL"
BASE COUNT         4273 a         2228 c         2628 g         3599 t
ORIGIN      
        1 agattgggtt ttcctacaaa atatttttat ctttgttgaa taggaaacaa aaaaacaata
       61 taatgaaaga aaaagaaggt gtagaaatgg ataaaagaca actgctaata gaagaatatc
      121 tggatttagc taatgagatt attcatcgta ataaaccaga aatggaaaaa gaatttgcag
      181 gatttactct aaatgaacta gaagtgattg aacatatcgg gaaaatccct gatcctaacg
      241 tgacaaaatt agcgaatgct agttacatga ctagaggagc catcagtaag ctaacaaaaa
      301 aactgatagc tagagggatc ataaacactt atcaaagcga agagaataaa aaagaaatct
      361 attttcaatt gacgccaatc ggacaaaaaa taaggaatag acacgagcaa ctccatcaaa
      421 aatgggtaca gcgagatgct actgtatttg aaaatatgtc aaaagaagaa tttgacacag
      481 tatttcgttt tatcggtcga tacagagaat ttatacgaag tagcaaatga agctactatt
      541 ttttattgta gtgataatag gcaaaaatca taagcaaaaa tccgaatacc gtcggaagaa
      601 atggtgctgc agcataaagc tgtcctgcga ttagcgggcc gatgacgcgc gatagagatt
      661 gtatactttg ggtaccgccc attacaagac cttgctggtt atctgagaca gaattggata
      721 gttggccatt gaatacagga gtaaaaatag aatcaccgaa accataacag ataatcccaa
      781 ataaaaacaa aatcggcagt agaagaattc cagataatgt gatgaataga taggcgagga
      841 tttcactgaa catccctatt cttgtgatct gctgttctga aaattttttg agcaatcgag
      901 gcataatgaa caattgcgag acagtatcca agattccaat caaagagaag cttaaaccaa
      961 ccaacccagc cttccactga aaggcgtcaa tcgaaaattg agaaaagata gattgaagag
     1021 agccagctgc caaccaaaca gcaaaacctg ctgtcaataa aggaataacg gatgaaatct
     1081 tgaataattg ttgtaattgg tgaaaaggtc ttacatggga gaaacttaaa tctactgaac
     1141 gtttttttat tggaaggctt tctagcataa atgtgtagcc ataaacggca tttaagaaag
     1201 taaagagtgc tccaataaat ataggaacag aattccccaa ctcagctaat agacccccta
     1261 taataggacc cagcgttgtt cctataccga ctaaagcacc catccatcca aaaactttgg
     1321 ttctttcatt aggttccgtg atgtcggcaa agtaagcata taaggtggag atttctcctg
     1381 ccgtcaatcc ttcaatgata cgaccaagga acaacatcca tatcgaattt cctaaaccaa
     1441 aaagcaaata tccgatactt gatcctaata aactgataat aaggatcgga tgacgcccaa
     1501 aatgatcact taagctaccg agaatggggg cagataagaa ggcagctaga gcataaacag
     1561 acatgagcaa agtgatatag aaagcttgct gatgtatgga gtgagaataa ggcagcgtta
     1621 aaaacggaag tacaggactg acgatagtaa atcctaatcc agtgaataag acagagacgt
     1681 atccaaaaac tttagaatgt ttatttgtga aactgtacat gtaaaaactc ctttatgcaa
     1741 taatgttaac ttggaaacaa aaatagtgta tagtaatttt gtttccttgt caacattcta
     1801 aggaacagcg aaatctactt aatttattta ttccgaaaag tgaagatacg catcaaaaac
     1861 atgaacaaac aaaaatcaag tagacgacat tgtaaatctg accgatcagt gaagtaaata
     1921 gaaaagaaac ctgttcttgc ttcccatgtt ttttttacgt atactgtgat tgagcggagg
     1981 agaaatcatg ttgaatttag aaaattactt aagcgctgga caaacagtca tatctaatct
     2041 tttacttaaa aattatcata ggatcggtct acaatctgaa gaatttttat ttgttctaca
     2101 gttgcatatg gcacagcttg aaggagatac tttccctgat ttgcagatga ttgctatgga
     2161 tatgggaatc aaacaagatc agatttttca aatactggat cgtctcgtaa caaatggatt
     2221 tatcaagata gaaacgacga ttgtcaacgg taaaaaagca gatcgatata atctttaccc
     2281 catctatgat ctattaggtg agtatttaaa aacacaagaa aaaaaatacg aagaaaaaac
     2341 acaagaaaaa gaaatccagt cagtgtatca attatttgaa caagaatttg gacgcccgct
     2401 ttcttcgatc gagttccagc ggatcggaca atggctagaa gaagaccatt atcagccgga
     2461 aattttgaag ctagcactgc gggaagccgt attaaatcag gcttatagtt ttaattacgt
     2521 tgaccgcatt ttgctatcgt gggaaagaaa aaatctacgt acaaaacaac aagtggaaga
     2581 agaccaaaaa cgaagaaaac agcagcttct tcaaagagaa gtagaacagt cagctcaaca
     2641 agaagaattg ccgaaagtct cactgaaaaa ttggttggag gagtagcgga atatgttaag
     2701 caaacaaaaa acaatggaag ctctagaaac gatgtatgga atgtttcccg aagcacatgg
     2761 agaactcaag cacaataatc catttgagtt attgattgca gtgatcttaa gtgcccaggc
     2821 gacagatgta tcagtgaata aagcaacgcc agatttgttt gcctcttttc cgacacccga
     2881 tgcgttagca gaagcttcaa tcgatgaaat cattcttaaa ataaaaacga ttggtttgta
     2941 tcgaaataaa gcaaaaaaca tcaaagcgtg tgcacagcag ctgattgaac gtttcgatgg
     3001 gcaagtgcca acgtcaagag aagaattgat gtctcttcct ggtgtaggca gaaagacagc
     3061 aaatgtcgta ttgggggatg cattcgggat accagcaatc gcagtagata cccacgtgga
     3121 acgtgtctca aaacgcctga ggatctgcaa actagatgct acggtcatgg aagtagaaga
     3181 aacactgatg cggaaagtac cacaagaatt atgggtaaag acacatcata cactgatttt
     3241 ttttggtaga tatcattgca cggcaagaaa tcccaagtgc gaggtatgtc ctttgctatc
     3301 aatatgtcaa gatgggaaaa atcggatgcg tctaaaagaa aaggcgctaa aaaagaaacc
     3361 acgcctgtag acgtggtttc tttaattgca aataaatgta tgaattatct tgttattatg
     3421 gagaaaagct gtttcgttta tcttttttgc atgaaaaagt aaatgtacat actcagtagc
     3481 taggatggta acttattaca atttattgcg ataaaaataa aagttgttat ttttattggg
     3541 aaaatacccg atgtagaaaa taatgccttc caatatacct ataaaataag tccagtattc
     3601 caaaggatta tataaataag tgacgtatct atctaaaggt gtaataaaaa tgataagtga
     3661 taataaaaaa ataccattta taactaaaca taaactaatg gatttgggcg gtttcaggct
     3721 catcagaaaa atatagattc tggtgaacaa caaccataaa aaagtgagaa tcattgcatg
     3781 agagcttctt tccataaatt ttcctttaag agtagtgctt aaaagtacag aaaaaataat
     3841 aaatgcaagg ataggagcaa ttaaagtaaa tttatttaat aataaacaaa atttttcagc
     3901 ttttttattc ttggaataac gaggtattgt tttcgataaa aaaagatggt gcagacaaat
     3961 tatgataatt aagcatacta tcagataact caaaatgaag ccttctttca aaaaattatt
     4021 caaaaccata tattgtattt tttatttgat aataacaatg ggattattaa gaagtggcac
     4081 taaataaaag actagtgtgt atttagccga tttaattata aacaagtaaa tggataaagt
     4141 atatgtaatg ataaaagaaa aatggatttt ctaattttta agctaaatgt tagatcacac
     4201 atgtatatgc tggatagtct tataaaaaat catgtaatac agcttggtac atgattttta
     4261 tttgtagctg ttttttacat agacacaaaa aagaaaccac gcttgtagac gtggtttctt
     4321 ttttactatc tgtttccaga agctgaggtg ctgctggatg gtgtatggtc atttgcagca
     4381 tccgctccgc tagttgctgg ctcactggaa gaagcaggag gagcagatga agacggtgtc
     4441 gagctttctt cggatgaaga agaaggaacc gttgttgaag acgctggctc gcttgtttct
     4501 gctgtcgtgc tttcttttga ggactcagca gttgattcgc tttgactagt agagctagag
     4561 ctttgagtcg ttgtctctgt tgttgagctt ccaggagtct ggacatagct ggaagatgga
     4621 atagttgttg atggtgtaat tgcattcgat ctagctgtat attgatcttt gtagtacagt
     4681 tcaccgccca cacgaattaa tccgcttggc atctcccagt ctgtatttgt cacgttagct
     4741 gaaacatact gcataagctc gcgataaaca tcagaggcta cgtgtgacga ttctgaagtg
     4801 acaggcgtca tttttttatt gtaacctgtc cacacggaaa tcgaataatt tggcgtatag
     4861 cccgcaaata ggatatctgg atacacccca gaagaaatac caagttttgc atactcgtca
     4921 tctgtgtaat tggatgttcc ggtcttaccg gcttgatata acccagcgat ttgcgcattc
     4981 gtaccagttc cttcagtgat cgtatctttt aaaatgtctg tgatcatata agctgtttct
     5041 ggagacatgg ctgtttttcc atctggctca taagtttctt ctgttccgtc ttggaagacg
     5101 attttattaa catattgagg tttgtaataa gtccctccat tggcgaaagc cgcataggct
     5161 gctgccattt ttaaggaaga agctccgtat tttgtcccat cttgttcttc cgtattacta
     5221 gagatcgcat tcgattgatg gatcgtactg tattcgatcc caagattttt taagaaagaa
     5281 gccactttat ctgaaccgac ttcattgaat aatttgactg ctggaacatt acgggataag
     5341 taaagtgctt ggcgtaaagt aatggtgccc atatattgat tatcccagtt tcctacagga
     5401 gtcgaagtcc cttcatagtt atacggtgcg tcagtaatag tttttccagt agaatatttc
     5461 aaatattcaa aagctggtcc gtaatctgtg acaggtttca tcgtagaacc aaaatcacgg
     5521 gaagtattca ctgctaagtt gttgcctaaa gttacgtctt ctgcgatgtg acgtccgcca
     5581 atctgggctt ttactttccc ggtattggtg tcgataaggg tggaggcaac ttgcatctcg
     5641 tcgtctgggt aagagacata ctgatccgtg ttgacgatat catatagttt cttttgggcg
     5701 tccagatcca aattcgtata aatctctaaa ccgtctgtgt agacattctt atctgttttt
     5761 tcttgtactt cattgatgac ttctttgaca taattatcga cgatcttagt attgtcatcg
     5821 gattgagtta gttcttgcag accatccgtt accggtacat taacagcttg atcatattct
     5881 gtttgagaga ttttttcgtt ttgaagcatc gtatacaaaa cagtatctcg tcttttcttc
     5941 gcctgatctg gataaacata aggatcatag gcggaagggg cttgaggcat cccagcaagc
     6001 aatgctgttt gcggtaaaga aagttctgat aatttcttac caaagtacat ctcagaagct
     6061 gtctccatcc cgtacaagcc gtttgacata tacactttat ttacgtagta ggtcaagatc
     6121 tcttgtttcg attttttttg ttccaatctt acagccatcc acgcttcttg ggccttgcgt
     6181 ttcagagtct gatcctcggc actggtggag aagaaggaaa gtttgatcaa ttgctgtgtc
     6241 aaagtacttc cgccttgcag tccgccagag gtaaagttag agagggcaga accgatgatc
     6301 cgaatagggt caaccccgat gtgtttataa aaacggcgat cttctaccga cacgatcgca
     6361 tcttctaatg ttttcggtaa ttcattcgca gaaatttttt cacgcttttc tgcgcctaaa
     6421 tcttcgaata gttcgccatc ttgtgtatat agtttggaag atacggtagc gtctaatttt
     6481 ttatccgtca attcgggcgc atcttttgcg taataccaga aaagtcctac acctgctaaa
     6541 aagaggatac agaaaaatga gagtattcct aaaaggatct tgataaataa tcctttttta
     6601 tgtgttccag aggactttcc agaacctttg ccagaattct tcttcacact ctttttagga
     6661 gtaggctgtt tctgtcgtct agagcttcta gtttgttcat ttgccattct tgctttctcc
     6721 ttcaatagat aatgttgata aatagaagtc aaccgcgtcc aaataaggaa tccgcggaga
     6781 aataccagtt ttgatctcta ttcctagttc ttcgatcaaa gataaaggta gtgatttgcg
     6841 tcctttttcc ttttgggcgt cccagtaagc aatcaaatga acactattca aataaaaaca
     6901 gcgcttcaaa gacgaaaacc ataacaagac aaagcagacc ccattttgtt cgaggcatgc
     6961 tttcatatgt tcgatttgat gggcatggaa gtttttaaag ggaaaagatg ttttgttctt
     7021 ggtttctttt gcttcaaagt ccaagtaaaa gcctcgatag acgccattat agtctgtagt
     7081 tgaggcttgg gtaaagtagg cttccttgat cacagcagca cttctcttag gatagtctac
     7141 tttcacgatt tggatagggg taggcttttt atggataacc gccaacccgc gggaaagata
     7201 atatttatta ctttcattga ttgcttcttc aaagcgcatc ccccgattgc cgaattcagt
     7261 gatctgattt cttttttctt gaattttttc gacgggagag gcattcttat aataaggttg
     7321 gccatttgga tagcgcaata ccatctttaa tcacactcct aggccacatt atagcaaaaa
     7381 agcggataga aagaaaagga atctgagatg gataagtcaa aagtaatcta tgtgtctggg
     7441 tatcgaagtt tcgaactcgg tgtttttaaa gaaaatgatc ctaaaatcca agttgttaaa
     7501 aatgttttaa aaaaagaact ccatcagtta gcagaagaag ggctggaatg ggtacttgtc
     7561 agtgggaatt tgggcgtcga actatgggct gtgcaaatag tagcggaatt gaaagaagaa
     7621 tatccggaac tatctcttgg tattttgtat cctttttctg attttggtaa taactggaat
     7681 gaagggaacc aagaaaaaaa acaattagca gaacaattag cagattatgt cgaagctgtt
     7741 agccatcaac cctaccaatc acctagtcag ctaaagaatc acactcgttt tatacttgag
     7801 catacagtgg gctgtctgct gatctatgat gaagaattcc ctggaaaaac gaagtatttt
     7861 tttgaagatg cacagaatta ccaagcagat catccctacg aaattcggct gatcagtatg
     7921 gacgatcttc aaaattttag tgaataatcg atattgtgtt tgatttatca acttttttcc
     7981 tatacaatga aaaaggtaga aatgttatta cgtaaatgaa aactagaggt gtaaatatgg
     8041 cgaatttggt ttatagtcct aaagacattt tacaacaaga attcaaaaca aaaatgcgcg
     8101 gctatgatcc cgttgaagtt gatgaattct tagacaatat catcaaagat tatgaaactt
     8161 acagcaaaga actccttgct ttacaagaag aaaacgatcg attgagtgca aaagtagctc
     8221 aattatctaa aactcaagga gcagctcaaa cacgcgtgca acaaacagag gcaccaaaga
     8281 gcgcagcagt gaccaatttt gatatcttaa aacgcttgtc aaatcttgaa cgtgaagtat
     8341 ttggtaaaaa gcttgatcaa caagcaagtg cagtcaaacc agcacaacct aatccaaata
     8401 actacacaaa tgcagacaca agcttagatg ataatgaaaa aacacgtcaa ttttaatttt
     8461 tgattaatga atttgcggtt ttcgggtaat cgcggtctga cttgatcagg ctgaggaaag
     8521 tccatgctcg cacaggctgt gatgcctgta gtgttcgtgc ttagcgaaac cataagctaa
     8581 ggtactcttt ggagtaacgg caggaaaaca agctaaggct tcggctatgc ttaagtatcc
     8641 ttgaaagtgc cacagtgacg aagcggctgg ggaaacccat ccggtggaac gcggtaaacc
     8701 cctcgagcga gcaacccaaa caatggtagg ggcgcttttt gtctggaaga agaacaggac
     8761 aaaaaggcag tataactgca gatagatggt taccgctttg ttttttctcc ctggaaaagc
     8821 aaagtacaga acatggctta tagaaaaccg caaacatcag ggaattaggt cgtgacaaaa
     8881 gtaatgcgtt ataagaaaca agaaaaacat ttgaaagcta tttttcaata cttcagatga
     8941 atcgttctta ttacaaaaca aacttttgta tcaccggtta ttcggaattt gagtaaaagt
     9001 gtggggtagg actgatgtcc cacctccttt ttttataaat aaggagattg tgtatggaaa
     9061 aaaacaggaa gttcaacctc gtcgcaactg cggcaagcgg gctagaagca ctggttggta
     9121 aagaattaag agatcttgga atcgaatgcc aagttgagaa cggacgtgca cgttttgaag
     9181 gaacaatgga aacgatcgct acagctaatt tatggttacg tacagcagat cgagtaaaaa
     9241 tcgtggttgg ggaattcgat gcgtatacgt ttgatgaatt gtttgaaaac gtaaaagcat
     9301 tgccttggga agattttctt ccactagatg cagcttttcc tgtagctgga aaatcgatca
     9361 agtcgaaact atatagcaca cctgattgcc aagcgatcac aaaaaaagca atcgttgaac
     9421 gtctccgtac ctattatcac cgtccagctt ctgtaccact gacggaaact ggcgcacatt
     9481 ttcagttgga agtagctttg ctgaaagacc atgtgatggt aactctggat acgacaggac
     9541 caagtttatt caaacgtggt tatcgcttag aaaaaggtgg agcaccattg aaagaaaaca
     9601 tggcagcagc acttattatg ttgacaaatt ggcgaaaaga ccgtccattt tatgatcctg
     9661 tatgtggttc aggtacgctt tgtattgaag cagccttaat aggccataat atcgcaccag
     9721 gattcaatcg tgagtttgct tgcgaatctt gggattggtt cagtcaagaa atcatggaaa
     9781 atgttcgatc agcagccgaa gaaaaagcag attatgatat tgaattagat attactggtt
     9841 cagatatcaa tggacggatg attgaaattg ccaaagccaa tgcagaagaa atcggattag
     9901 gctcttcgat tacctttaag caacaagcag tcaaagactt caaaacggat aaagaatacg
     9961 gggtcatcgt ggctaatccg ccttacggag aacgtctagg agaagaagaa actgttcgga
    10021 aattatataa agaaatgggc gatgtattcc gtccattaaa aacatggagt aaatatatct
    10081 tgactagcga cttagcgttt gaggaatttt acggacaaaa agcaaccaaa aaaagaaaat
    10141 tgtacaatgg tgcattgcgt acggatctat tccagtattg gggaactcgt ccgcctagaa
    10201 aaaaagagaa agacgaataa tcttactaat tgattcattc aattggatgt ttggaggaat
    10261 agggaatgaa agaaaaagag tttttacaag aagtaaaaga aatcaatctt ctacaacaag
    10321 ctttaggaat cctcgattgg gatacacaaa caggtatgcc tgaaaaagct agtgcatacc
    10381 gaagtgaagt agacagctat ctttacagca tttatttttc aaaaaaaatc ggtccaaaaa
    10441 tcaaagaagc cattcgctat ttttctgaac atccggaaga attgtcggaa gttggaactg
    10501 ccgtttttgc caaagtaaaa gaagagtatg atttggaaca tcgcgtaccg gaagatctta
    10561 tgagaaaata tacagctgcc gtttcttcag cacacggaca atggcaaaaa gctagagaaa
    10621 cacaacaatt ttctgatttt caacacgcat tgaatcaaaa tattgaatta acaaaacagt
    10681 tgatacctta ctggagaaaa gatgaaaaga cgaattatga tgttttgctg aatcaatacg
    10741 aacccgggat gactgtcgaa atccttgata aggtatttga tcagcttaaa gaaggaattc
    10801 tttcgatccg ccgtacgctc caagaaaaag ggactgaacc tgaaacagac tttttaaatc
    10861 ggagaatgac gaaaaaacaa cagaagagat ttgtagtgaa agtaatcgaa caacttggtt
    10921 atgattttag tcgtggtcgt ttagatgaca ctgtccaccc atttatgact ggaattaatc
    10981 cgaatgatgc acgaatcacg acacgatgga acgaaacaga tttcaaaatg gctgtttttg
    11041 gagtgatcca cgaggctggt catggtatgt atgaacaaga catcgatgat aaatatgcgt
    11101 atacaccggt ttatgaaggt acatcaatgg gtatccatga atcacaatcg ttgtttaacg
    11161 agatcattat tggaagtagt cgcagcttct ggaaaaagca atatcctttc tttcaagaat
    11221 gtgcagaagg aacattcgat gatattcctt ttgacaaatt ttatcgttca ttgaaccata
    11281 caaaatcaag tttggttcgt atcgaggcag acagtttgac ttaccctctc catatcatca
    11341 ttcgttatga aatcgaaaaa atgattttca atgaaggggt agatgttgct gaactacctg
    11401 aaatatggaa tcaaaaatat gaagagtatc tgggaatacg accaacaaat gatgtggaag
    11461 gcatcctaca agacgttcat tggtcaggtg caagctttgg ttattttccc tcttatgcat
    11521 tagggtacat gtatgcggca caattacttc attctttgca gcaagaaata gatgtggaaa
    11581 atgttctagc gtcagacgat tattctccaa tcaaaaactg gatgtcagag catatccatc
    11641 aatatggtgc atctagaaaa ccaaatcaat taatcatgga tgcaacacat gaaccgctta
    11701 atccgcaata cctgatcgac tatatgaaag acctgtattt taatgtatat caggtaaaat
    11761 aaaatacaat ttacaaagat agctgaaatt catctaatct atagatgttt tcagctattt
    11821 acttaagaaa gaagtggaac gaatggataa attacaagtg atcgctgatt atagtatgga
    11881 ccaattagcg catgatcaaa caggacatgg gagcgatcat accaaaagag ttgtcaagtt
    11941 agctgaaaaa attttggaga cggaaccgca ggcagaccgc tttgtgacgc ttgcagcagc
    12001 ttacctacat gatacgattg atgataaagt cgttaaaaat gagaacgagg caaagcaaca
    12061 gcttcgtgta ttccttcgct ctttgccaat agtagaggaa cagatctcga tgattttttc
    12121 cattatcgaa aatatgtcct tttctaaaaa tctctctgaa gcggccgaac tatctctgga
    12181 aggtaagatc gttcaagacg ctgatcgtat cgaagcatta ggagcaatcg gcattttgcg
    12241 tactgcttat ttcggcggtg gacatgggca cccgattttt gatcctgaac tgtatccgca
    12301 aacattcaag gacaaagaaa attaccgaaa aggcacgaca gtgatcaatc atttttatga
    12361 aaaactgttc ttgctgtctg ataaaatgaa tactgattac ggatatgaag aagccaaacg
    12421 aagagaaacc ttcatgcgtg aattcttaga agaatttttt ctggaatggt ctattgacga
    12481 tgaaaatttt actccagaca attggatcaa aaataacaaa aaatgatgga ggttgtgaca
    12541 gaagtggtca gctccaagat atttcggatc attttccgta aaagttactt ctggaacact
    12601 gtttaccaag aggtcgtgag cctgccgttc agctccgagt cacaaggaac aatttcaaaa
    12661 aatagcttct cgtgtttgat gaatattgta acttgtgatt cggaattggc aggagaacac
    12721 cgtttatt
//
LOCUS       DAZKKZ010000075        12195 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.077, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000075 DAZKKZ010000000
VERSION     DAZKKZ010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12195)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12195)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12195
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.077"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(78..635)
                     /gene="frr"
                     /locus_tag="ACG8LA_002414"
     CDS             complement(78..635)
                     /gene="frr"
                     /locus_tag="ACG8LA_002414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008135 - translation factor activity, RNA
                     binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HFQ0204691.1"
                     /translation="MADAIMTEAKEKMKKAAQNLQRELGQIRAGRANASLLDRITVNY
                     YGAPTPLNQMASIQIPEARVLMITPFDKSILQDVEKAIMASDIGISPTNDGNVIRLVI
                     PQLTEERRKELAKDVKKEAENAKIAIRNIRRDAIDEYKKQQKNGDITEDDLRGLEKDV
                     QTLTDNSIKEVDKIAADKEKELLEV"
     gene            complement(638..1360)
                     /gene="pyrH"
                     /locus_tag="ACG8LA_002415"
     CDS             complement(638..1360)
                     /gene="pyrH"
                     /locus_tag="ACG8LA_002415"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0033862 - UMP kinase activity [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HFQ0204692.1"
                     /translation="MVTPKYQRVVLKLSGEALAGDAGFGIKPPVIKEIIQEIKEVHEL
                     GVEMAIVVGGGNIWRGQIGAQMGMERAQADYMGMLATVMNALALQDTLENVGVPTRVQ
                     TSIEMRQIAEPYIRRKAERHLEKGRIVIFAGGTGNPYFSTDTTAALRAAEIGADVILM
                     AKNNVDGVYSADPKVDANAVKFEELTHLEVIAKGLQVMDSTASSLSMDNDIPLLVFNL
                     NEHGNIRRAILGENIGTTVRGK"
     gene            complement(1496..2377)
                     /gene="tsf"
                     /locus_tag="ACG8LA_002416"
     CDS             complement(1496..2377)
                     /gene="tsf"
                     /locus_tag="ACG8LA_002416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation elongation factor Ts"
                     /protein_id="HFQ0204693.1"
                     /translation="MADVTAKMVKELREMTGVGMMDAKKALVEVEGDMEKAVDLLREK
                     GMAKAAKKNDRIAAEGLASVAVKGNTAAIVEVNSETDFVSKNEMFQDLVKEIAELVAE
                     NKPADMEAAMKIKTDKGTIESDLIEATQVIGEKISFRRFEVVEKDDNAAFGGYLHMGG
                     RIAVLTVLDGTTDETVARDVAMHVAAINPRYVNESQIPEAELEHEKTVLTEQALNEGK
                     PANIVEKMVEGRLKKFKAEIALVDQPFVKDPDMTVEKYVASKGATVKTFVRFEVGEGI
                     EKREDNFVEEVMSQVKK"
     gene            complement(2476..3258)
                     /gene="rpsB"
                     /locus_tag="ACG8LA_002417"
     CDS             complement(2476..3258)
                     /gene="rpsB"
                     /locus_tag="ACG8LA_002417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HFQ0204694.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMKKYIFTERNGIYIIDLQ
                     KTVKLVDAAYDYMKSVAEEGGVALFVGTKKQAQEAIKEEATRAGQYFVNHRWLGGTLT
                     NWDTIQKRISRLKQINAMEEDGTFEVLPKKEVAGLNKERERLEKFLGGIADMPRIPDV
                     MYIVDPRKERIAVQEAHKLNIPIVAMVDTNCDPDEIDVVIPSNDDAIRAVKLITSKMA
                     DAFIEGNQGEDQVVEEDFTEENTATSIEEIVDVVEGDNSSAE"
     gene            3617..4096
                     /locus_tag="ACG8LA_002418"
     CDS             3617..4096
                     /locus_tag="ACG8LA_002418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HFQ0204695.1"
                     /translation="MRKAQRHLLIKQVIEEFPIRTQEELLNKLGHYGVTATQATISRD
                     IRDLKIVKAPDENGVSRFVLFREKGTPETRTEEEDRLVQMIEDIVLKVERVHFLTIVN
                     TLPDNAHLFASVLDEIKPPSIVSTIAGFDTIMVISENEEDAKRVEEFLHHPTEVSLF"
     gene            4313..5404
                     /gene="phnW"
                     /locus_tag="ACG8LA_002419"
     CDS             4313..5404
                     /gene="phnW"
                     /locus_tag="ACG8LA_002419"
                     /EC_number="2.6.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047304 - 2-aminoethylphosphonate-pyruvate
                     transaminase activity [Evidence IEA];
                     GO_process: GO:0019700 - organic phosphonate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate--pyruvate transaminase"
                     /protein_id="HFQ0204696.1"
                     /translation="MYKLLTPGPLTTSETVKNAMLIDHCTWDQEYKEITQWIRKKLLD
                     LAQVSEGIYTTVLMQGSGSFGVESVLSSVIRPEDTVLICSNGAYGQRMINMCECLKLN
                     YTVYEVSEHQILQAHVITQLIEENPSISALAMVHSETTSGILNNLEEIAAVTQEKDLL
                     FIVDAMSSFGGIPIRVAELGIDFLISSSNKCIQGVPGFSFVLANKAELEKRKNVSRSL
                     SLDLYDQYRVMENENGKWRFTSPTHTVLAFQQALKELEAEGGIETRYSRYLANNHVLR
                     QKMTEMGFQPFIQEYQGPFITSFLYPKDWRFDFNHFYQYLKQNGFVIYPGKISDHECF
                     RIGNIGEIYPEDILELTAIIKDYKENVND"
     gene            5397..6182
                     /gene="phnX"
                     /locus_tag="ACG8LA_002420"
     CDS             5397..6182
                     /gene="phnX"
                     /locus_tag="ACG8LA_002420"
                     /EC_number="3.11.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050194 - phosphonoacetaldehyde hydrolase
                     activity [Evidence IEA];
                     GO_process: GO:0019700 - organic phosphonate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HFQ0204697.1"
                     /translation="MIKTVIFDWAGTTVDFGCMAPVHAFRNAFLEKGIQLTDKEIREP
                     MGKLKWDHIQQLLSLPSVKKQWIAIYGQLPQEKEVEELYQQFEHYLFKDLVKHSTLKP
                     DTLETIERLRNAGINIGSTTGFTAPMMTIVAETAKKEGYSPDFMATSEDVEGYGRPFP
                     YMIHKNMQYFKNKSVDEVIKVGDTVSDIQEGKNAGVLTVGVIEGSSLMGISYDEYQKL
                     EMGKKDRLKQSVALRFQQAGADICVNNLKELTEYILYADKNPE"
     gene            complement(6528..8219)
                     /gene="argS"
                     /locus_tag="ACG8LA_002421"
     CDS             complement(6528..8219)
                     /gene="argS"
                     /locus_tag="ACG8LA_002421"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004814 - arginine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006420 - arginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HFQ0204698.1"
                     /translation="MNNKDLVAKAVYDAVKDDLTLEQVEQLLENPKSAEHGDVAFPAF
                     SLAKVYRKAPQQIAADLAEKIDSANFEKIEVVGPYLNFFMNKELISKKVLQTVVKEKE
                     HYGDSNIGNQGTVPIDMSSPNIAKPISMGHLRSTVIGNSIGFIMEKIGYQPIRINHLG
                     DWGTQFGKLIVAYKKWGTEEAVKAEPINELLRLYVQFHEVAETEPELNEEARAWFKRL
                     EEGDEEAIQLWQWFRDESMKEFNKIYDLLEVRFDSLNGEAFYNDKMDEIVKLLEEKHL
                     LNEDKGAEIVDLSAYDLNPALIKKSDGATLYITRDLAAALYRKRTYDFKQSLYVVGNE
                     QSYHFKQLKAVLKEMGFDWSDDMRHIPFGLITQGGKKLSTRKGKIVLLEEVLNEAIQS
                     AKEQISEKNPDLENKDAVAKQVGVGAVIFHDLKNDRLNTFDFNLEEVVRFEGETGPYV
                     QYTHARAVSLLEKAGFVPSETADYALNDDTSWEVVKLVQKYPETVLSAGEKYEPSVIA
                     KHAIKLAQAFNKYYAHTKILADDEQKEARLALVYAVTVLLKEDLRLLGLHAPDKM"
     gene            complement(8641..9588)
                     /gene="arcC"
                     /locus_tag="ACG8LA_002422"
     CDS             complement(8641..9588)
                     /gene="arcC"
                     /locus_tag="ACG8LA_002422"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008804 - carbamate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HFQ0204699.1"
                     /translation="MAKRKVVVALGGNAILSTDASAKAQQEALMETAKYLVKFIEQGD
                     ELIISHGNGPQVGNLLIQQQAADSEKTPAMPLDTCVAMTEGSIGYWLQNAMGEVLKEK
                     GIDKDVVSLVTQVIVDENDPSFKNPSKPVGPFYTEEEAKEQMNADSTVTFKEDAGRGW
                     RKVVASPKPISIKEARVIETLVDQGVITVSVGGGGIPVVETATGLEGREAVIDKDFAS
                     EKLAEIIDADLLIVLTGVDNVYVNYQKPDQKKLETVTVSEMKQYIDEKQFAPGSMLPK
                     VEAAIAFVEAKPNAKAIITSLENIENLLASEEGTIIVAD"
     gene            complement(9703..10722)
                     /gene="argF"
                     /locus_tag="ACG8LA_002423"
     CDS             complement(9703..10722)
                     /gene="argF"
                     /locus_tag="ACG8LA_002423"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004585 - ornithine carbamoyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0042450 - arginine biosynthetic process via
                     ornithine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HFQ0204700.1"
                     /translation="MKESVFQGRSLLAEKDFTKEELQYLIDFSEHLKDLKKRGIPHHY
                     LEGKNIALLFEKTSTRTRSAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQKMVEELAEFSGVPVWNGLTDEWHPTQMIADFLTIQENFGTVEGITVA
                     YCGDGRNNMANSLLVTGAILGANMRIVAPKELQPEEEIVKMAEGFAEKSGAQLMITDD
                     VDKGVDGADVLYSDVWVSMGEEDKFEERIKLLKPYQINMEMVEKTHNTDRLIFLHCLP
                     AFHDTNTVYGEQMKERFGITEMEVTDEVFRSKYARQFDQAENRMHSIKAIMAATLGNL
                     FIPRV"
     gene            complement(10813..12042)
                     /gene="arcA"
                     /locus_tag="ACG8LA_002424"
     CDS             complement(10813..12042)
                     /gene="arcA"
                     /locus_tag="ACG8LA_002424"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016990 - arginine deiminase activity
                     [Evidence IEA];
                     GO_process: GO:0019546 - arginine deiminase pathway
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HFQ0204701.1"
                     /translation="MDKPIHVFSEIGKLKTVLLKRPGQEVENLTPDIMDRLLFDDIPY
                     LPIAQEEHDNFAKTLQNEGVETLYLEKLAAEAIDAGNVKEQFLNKMLDESHIASNAVR
                     EGLHEFLLSMETQEMVDKIMAGVRTKDIEVRSSSLYDLSADDDYPFYMDPMPNLYFTR
                     DPSASMGNGMTVNKMTFEARRRESMFTEYILKHHPRFANKGIEVWLDRENPDHIEGGD
                     ELILSDKVVAVGISQRTNAKALEKLARHLFAKNSGFEKVLAIKIPNNRAMMHLDTVFT
                     MVDHDKFTIHPAIQSKDGKMDVFTIEPDGDDIKITHSDNLHETMKAALGLDDLVLIPT
                     GNGDEIVAPREQWNDGSNTLAIAPGVVVTYNRNYVSNELLRSYGIKVLEINSSELSRG
                     RGGPRCMSQPLVREDLK"
BASE COUNT         3349 a         2535 c         2192 g         4119 t
ORIGIN      
        1 tttaattttt aaataaaaga aatataaata aaaacagagg aagcggaatg atccgcccct
       61 ctgtttttat gattttatta aacttccaat aattcttttt ctttatcagc agcgatctta
      121 tctacttctt taatgctgtt atctgtcaat gtttgtacgt ctttttctaa tccgcgcaaa
      181 tcatcttcgg taatatcacc atttttttgt tgttttttat attcatcgat cgcatcacga
      241 cggatgttac gaatcgcgat ttttgcattt tctgcttctt ttttcacatc tttagctaat
      301 tcttttctgc gttcttctgt cagttgcggg ataactaagc gaatgacatt tccatcattg
      361 gttggactga ttccgatatc acttgccata atagcttttt caacatcttg aagaatgctc
      421 ttgtcaaaag gtgtgatcat taaaacacgt gcttctggaa tttggattga tgccatttgg
      481 ttcaatggtg ttggcgcacc gtagtagttc acagtaatac ggtccaaaag gctagcgttc
      541 gcacggcctg cgcggatttg cccaagttca cgttgaagat tttgtgctgc ttttttcatt
      601 ttttcttttg cttctgtcat aattgcatct gccattttta tttccccctt acagttgttc
      661 cgatattttc gcctaagatt gcacggcgaa tatttccgtg ttcatttaaa ttgaagacaa
      721 gcagtggaat atcattatcc atgcttagtg aacttgcagt tgaatccatg acttgtaatc
      781 ctttggcaat aacttccaga tgagtcagtt cttcaaattt tactgcattt gcatctactt
      841 tcggatcagc agaataaaca ccgtctacat tgtttttagc catcaggata acatctgcgc
      901 cgatttctgc cgctcgtaat gctgctgttg tgtctgtcga gaagtacggg ttgccggtac
      961 cgcctgcaaa gataacgatc cgtccttttt ctaaatgacg ttctgcttta cggcgaatat
     1021 atggctctgc gatttgacgc atttcaatcg aagtttgcac gcgtgtcggt acacccacgt
     1081 tttccaacgt atcctgtaaa gctaaggcat tcataactgt agctaacata cccatgtaat
     1141 cagcttgagc acgttccatg cccatttgtg ctccgatttg tccgcgccag atatttccgc
     1201 cacccacaac gattgccatt tcaacgccca gctcgtgaac ttctttgatt tcttggatga
     1261 tttctttgat tactggtggt ttgattccaa atcctgcatc cccagctaaa gcttctccac
     1321 tcaattttaa gactacacgc tgatatttcg gtgtgaccat gttcattcct ccaatatttt
     1381 ctattgccat tttaccatac ttagatgatt tcgacactct aagactggtt tttcttgttt
     1441 tgcttaaaaa aagggagcgc acaaaccgtg cgttcccgtc tgttattcaa cagaattatt
     1501 ttttcacttg gctcataact tcttctacaa agttatcttc gcgtttttcg ataccttcgc
     1561 caacttcgaa acgtacgaat gttttaacag ttgcgccttt tgatgcaacg tatttttcaa
     1621 cagtcatatc aggatcttta acgaatggtt ggtccaccaa agcgatttct gctttgaatt
     1681 tcttcaagcg tccttctacc attttttcaa cgatattcgc tggtttgcct tcgttcaatg
     1741 cttgttctgt aagaacagtt ttttcatgtt ctaattcagc ttctggaatt tgtgattcgt
     1801 ttacataacg aggattgata gctgctacgt gcatagctac gtctcttgca actgtttcgt
     1861 cagttgttcc atctagaaca gtcaatacgg caatacgtcc gcccatatgc aagtatccac
     1921 caaatgcagc attgtcgtct ttttctacaa cttcaaagcg acggaagctg attttttctc
     1981 cgataacttg agttgcttcg atcaagtcag attcaattgt acctttatct gttttgattt
     2041 tcattgcagc ttccatgtct gctggtttgt tttcagcaac aagttctgca atttctttta
     2101 ctaaatcttg gaacatttcg tttttagaaa caaagtctgt ttctgagttt acttcaacga
     2161 ttgctgcagt gttacctttc acagcaactg aagccaatcc ttcagctgca atgcggtcat
     2221 ttttcttcgc agcctttgcc attccttttt cacgtaaaag atcaactgct ttttccatgt
     2281 cgccttctac ttcaactaat gcttttttcg catccatcat tcctacgcca gtcatttcgc
     2341 gtagttcttt taccatttta gctgtaacgt ctgccatgtt taactcctcc tgtgtgtttt
     2401 tctttttaaa aaaagctgct tcaaaggaga gtgaggcttg tcgcccagcc tttgaaacag
     2461 ctccatcatt caaaattatt ctgctgaaga attgtcgcct tcaacaacat ctacgatttc
     2521 ttcgattgat gttgctgtgt tttcttctgt gaaatcttct tcaactactt gatcttcacc
     2581 ttggtttcct tcgatgaaag catcagccat ttttgaagta atcaatttaa cggcacgaat
     2641 tgcatcgtcg tttgaaggga ttactacgtc gatttcatct ggatcgcagt ttgtatcaac
     2701 catagctacg attgggatat ttaatttgtg tgcttcttga acagcaatac gttctttacg
     2761 tgggtcaacg atgtacatta catctgggat tcttggcata tcagcgatac cgcctaagaa
     2821 tttttcaaga cgttcacgtt ctttgttcaa accagcaact tcttttttag gtagaacttc
     2881 aaaagttcca tcttcttcca ttgcattgat ttgtttcaaa cggctgatac gtttttggat
     2941 agtatcccag tttgtcaatg ttccgcctaa ccaacgatgg ttaacgaagt attgtcctgc
     3001 acgagttgct tcttctttga ttgcttcttg tgcttgtttt tttgtaccta cgaataatgc
     3061 tacgccgcct tcttcagcaa cgctcttcat gtaatcataa gctgcatcta ctaatttaac
     3121 tgttttttgc aagtcaatga tgtagattcc gtttctttct gtgaagatat atttcttcat
     3181 ttttggattc cagcgacgag tttggtgacc aaagtgtacg ccggcttcta gtaattgttt
     3241 catagaaatt actgccatgt ttgtttcctc cgatttggtt ttatttttcc tcttcttatc
     3301 ttctaccttg ccggcaaact ttttcaagca cctaccgaca atccaataag aatgtggatt
     3361 tgctgatgca taaagcaccc tcagctatta tacagacaaa agatccgtat cgcaagagca
     3421 aatatacttt tctgctcaac attcaatagt ttacctgaaa gataaaaaga attcaagaaa
     3481 aacagtagat ttctctttgt ttctttatta tcctttttcc ataaaataat tttaggtata
     3541 aaagacgaat attattgggc aatccttctt ttttttgtta tgatacatgt gaaatctttc
     3601 gtaaaggaga aagaaaatgc gcaaagctca aagacatttg ctgattaaac aagtcattga
     3661 agaattcccg atccgtacgc aagaagaact attaaacaaa cttgggcatt atggcgttac
     3721 cgccacgcag gcaacgattt ctcgagatat ccgtgatcta aaaatcgtga aggcacctga
     3781 tgaaaatggc gtttcccgct tcgtattgtt tcgcgaaaaa ggaactcctg agactaggac
     3841 tgaggaagag gatcggctgg ttcaaatgat tgaagacatt gtattgaaag tcgaacgagt
     3901 ccactttttg acgatcgtca ataccttgcc agacaatgct catttatttg catctgtttt
     3961 agatgagatc aaacctccct ctattgtcag tacaattgct ggattcgata cgatcatggt
     4021 catctcggaa aatgaggagg acgcaaaacg agtagaagaa tttcttcacc atccaactga
     4081 agtatcactt ttttaatcag agcacgtatt cctaatatgg aatgcgtgtt tttttatttt
     4141 caatattttc cttattaaat aaacctttac actctttaca aaaatacatc attttttatt
     4201 caattttttc aacaccttga ttgaatcaca ataatcatca tttatattgg atgttaacaa
     4261 gagcagcttc ttgctctttg tgtatttcaa aaaagaaatg aaaggaaatc atatgtataa
     4321 attattaact cctggaccat tgacgacttc tgaaacagtg aaaaatgcta tgctgatcga
     4381 tcattgtact tgggatcaag aatacaaaga aattacacaa tggataagaa aaaaattatt
     4441 ggatcttgct caagtatcgg aaggaatata cacaacggtc ttaatgcaag gtagcggctc
     4501 ctttggggta gaatcggtat taagttctgt gatcaggcca gaagatactg tactgatttg
     4561 ttcaaacggc gcatatggac aacgaatgat caacatgtgc gaatgtctga aactgaacta
     4621 taccgtttat gaggtatcgg aacatcaaat cctccaagct catgtgatta cacagctgat
     4681 tgaagagaat ccctctatct ccgcactagc aatggtccat agcgagacta cttccggtat
     4741 tttgaataat ttggaagaga ttgctgctgt cacacaagaa aaagatcttt tgtttatagt
     4801 ggacgcgatg tcaagctttg gtgggatacc gattcgtgta gccgaactag ggattgattt
     4861 tttgatttcc agctcaaaca aatgtattca aggtgttcca ggcttttctt ttgtacttgc
     4921 taataaagcg gaactagaaa agcgaaaaaa tgtgagtcga agtttgtcac ttgatctata
     4981 tgaccagtac cgcgtgatgg aaaacgagaa tggcaaatgg cgtttcactt cccctaccca
     5041 tacggttttg gcttttcaac aagcgctgaa ggaactagag gcagaaggag gaatcgaaac
     5101 tcgatattca cgttatctcg ccaataatca tgtactacga caaaaaatga cagagatggg
     5161 gttccagcct ttcattcaag aatatcaggg gccattcatc acctcttttc tttaccctaa
     5221 ggactggcga tttgatttta atcattttta tcagtattta aagcaaaacg gatttgtgat
     5281 ctatcccggg aaaatcagcg atcatgaatg ttttcgtatc ggaaatattg gcgagatcta
     5341 tccggaagat attttggaac tgacagcaat tatcaaagac tataaggaga acgttaatga
     5401 ttaaaactgt aatttttgat tgggcaggaa caactgtgga ctttggctgt atggctcctg
     5461 tccacgcttt tagaaatgct tttctagaaa aaggaatcca actgactgac aaagaaatcc
     5521 gcgaaccgat gggaaaatta aaatgggatc atatccaaca gcttctttcc ctcccttctg
     5581 tcaaaaaaca atggatagct atttatggac aactacctca ggaaaaagag gtggaggaat
     5641 tgtatcaaca atttgaacat tatctgttta aagatttggt caagcattct accttgaaac
     5701 ccgacacatt ggaaacgatc gaacggttga gaaacgctgg gatcaatatt ggttccacga
     5761 ctggatttac tgctcctatg atgacaatcg tagcagaaac cgcaaaaaaa gaagggtatt
     5821 caccagactt catggcaact tctgaagacg tcgaagggta tggtcgaccg tttccttata
     5881 tgatccataa aaacatgcag tacttcaaaa acaagtcggt tgatgaagta atcaaagtcg
     5941 gagatacggt ctcagatatc caggaaggga aaaatgccgg agtgttgaca gtaggtgtaa
     6001 ttgaaggtag ttcgctaatg gggatttctt atgatgagta ccaaaaatta gagatgggga
     6061 aaaaagatcg tttaaaacag tctgttgctc ttagattcca acaagctggc gctgatattt
     6121 gtgtaaacaa tttaaaagag ttaacagaat acattttgta cgctgacaag aatccagaat
     6181 gacttttata caaaatcaga ggtcgtgaaa aagctgtact gcatcaagta ataagaacag
     6241 ccaaacaaaa atagctcctc atatttttcg tttggttagg cttattaccg cagatgcaag
     6301 cttttgaaca ccgtttattc gaaaaaaaaa gggagctgtg acacgacttt tgtcacagtc
     6361 cccttattta caaacaaaca gtgtttaaga gacaacctct ccactaaacg gtgttcattc
     6421 agctgactct cggtatttgc tcaaaaaacg ataaaatttg aaaagctatt ttctcttttg
     6481 tttctctaat actcggatca gaacgctgat ttcacattct ctttttctta catcttatct
     6541 ggtgcatgaa gtcctagcaa acgaaggtct tctttcaata atacagtcac tgcataaact
     6601 agagctaagc gtgcttcttt ttgttcatca tcagctaaaa tcttcgtatg agcatagtat
     6661 ttgttgaatg cttgtgctaa tttgattgca tgtttcgcaa tcactgacgg ttcgtatttt
     6721 tccccagcag acaagaccgt ttcagggtat ttttgaacta atttaaccac ttcccagctg
     6781 gtatcgtcat tcaatgcata gtctgctgtt tctgaaggga caaatcctgc tttttccaac
     6841 aggctgactg cacgagcatg tgtatattgc acataaggtc cagtttctcc ttcaaatcga
     6901 acaacttctt ccaggttaaa gtcaaatgta ttcagtcgat cgtttttcaa atcgtggaaa
     6961 atgactgccc caaccccaac ttgtttagct acagcatctt tgttttccaa atcagggttt
     7021 ttctcgctga tttgttcttt agcagattgg attgcttcat ttaatacttc ttctaataag
     7081 acgatctttc ctttacgagt tgataatttt ttaccacctt gcgtgatcaa accaaatgga
     7141 atatggcgca tatcgtcaga ccagtcaaag cccatttcct tcaagacagc tttcaactgt
     7201 ttaaaatgat agctttgttc attccctact acatatagag attgtttgaa gtcgtaagta
     7261 cgtttacggt acaatgcagc agctaagtca cgtgtaatgt atagtgtcgc accgtctgac
     7321 ttcttaatca acgctggatt caggtcataa gcagataggt caacgatctc tgcaccttta
     7381 tcctcgttca gcaaatgttt ttcttctaaa agtttgacga tttcatccat cttgtcattg
     7441 tagaaagctt caccgttcaa cgaatcgaaa cgtacttcca gcagatcata gattttattg
     7501 aattctttca tcgattcatc acggaaccat tgccataatt gaatagcctc ttcatcgcct
     7561 tcttccagac gtttgaacca agcacgagct tcttcattta attctggttc tgtttcagct
     7621 acttcatgga attggacata taaacgaagc aattcattga ttggttctgc tttaacagct
     7681 tcttctgtac cccatttttt gtaagcgacg atcagttttc caaactgtgt tccccagtca
     7741 cctaaatggt tgatgcggat tggctgataa ccgatttttt ccataatgaa accgatcgaa
     7801 ttaccgataa ctgtcgaacg caaatgtccc attgagattg gtttggcaat attaggagaa
     7861 gacatgtcga ttggtactgt tccttgattc ccgatattgc tatccccata atgttctttt
     7921 tctttcacta ctgtttgcaa aacttttttg ctgataagtt ctttattcat gaaaaagttc
     7981 aagtaaggtc cgacaacttc gattttttca aagttggcag aatcgatttt ttctgctaaa
     8041 tctgcagcga tttgctgtgg cgcttttcgg taaacttttg ctaatgaaaa ggctggaaat
     8101 gcaacatctc cgtgttcagc tgattttgga ttttctagta attgttcgac ttgttccagt
     8161 gttaaatcat ctttgacagc gtcatagaca gcttttgcga caagatcttt attattcatc
     8221 tttattcctc ctaaagtgct cccttgattg ttaaacaaaa aaaatctcta gcgacggcat
     8281 acttagtatg ccatcactag agacgagatt tcccgcggta ccactccaat tgtcctaaaa
     8341 aaggaccagc tccatctgat atcggtagac gaccgtctgt ttaaaacaga attctccaag
     8401 tgcgcttcgt tgtatcttct tcattcggct tccaccactt ccgaattcgc tagccaagaa
     8461 tgatacaagt actctcttgt tcaacaaatc ttagtcttat taaactttct tgaattatat
     8521 cagaaaaaaa aacgaaaggc tagtcgtttc tgataaaaaa acaatccaga tggcctaaag
     8581 gagaagaaat accacctgga tagctataaa tcatttcgta aatacgaaag acttaacaaa
     8641 ttaatcagct acgataatcg ttccttcttc agaagctaaa agattctcga tattttctaa
     8701 agaagtgatg attgccttag cgtttggttt tgcttcaaca aatgcaatag ctgcctctac
     8761 tttcggaagc atgcttcctg gagcaaattg cttttcatca atgtattgtt tcatttctga
     8821 aacagtaaca gtttctaatt tcttttgatc tggtttttgg taattgacat acacattgtc
     8881 tactcctgtc aatacgatca gcaaatccgc atcgatgatt tcggctaatt tttctgaagc
     8941 aaaatcttta tcgattacgg cttctcgtcc ttctaatcca gtagctgttt ctacaacagg
     9001 aatcccaccg ccaccaacag agactgtgat aactccttga tcgaccagcg tttcgatgac
     9061 acgtgcttct ttaatcgaga tgggtttagg ggaagcgact acttttctcc atccacgtcc
     9121 agcatcttct ttgaatgtca cagtggagtc agcattcatt tgttctttgg cttcttcttc
     9181 cgtgtagaat ggaccgactg gtttacttgg atttttgaat gaaggatcat tttcatccac
     9241 aataacttga gtgactaaag aaaccacatc tttatcgatc cctttttcct tcagtacttc
     9301 gcccatggca ttttgtaacc agtaaccgat agatccttct gtcattgcaa cacatgtatc
     9361 taaaggcatt gccggtgttt tctcagaatc agcagcttgc tgctgaatca ataggttacc
     9421 gacttgcgga ccatttccgt gggagatgat caattcatct ccttgttcga taaatttcac
     9481 taaatacttt gctgtttcca ttaacgcttc ttgttgggct tttgcacttg catccgtaga
     9541 caagattgca ttacccccta aagcgacaac tacttttcgt ttggccattt cattcgtcct
     9601 ttcttcagtt ctaccgaatt ttctagataa caaaacgagc cagcgttttg tgattttccc
     9661 tcaatgctga ctcgtttttt cgtgagatga atgtggttat gcttaaacgc gagggataaa
     9721 caagttacct aatgttgctg ccatgatcgc tttgattgag tgcatacgat tttctgcttg
     9781 gtcaaattga cgagcatatt tgctgcggaa gacttcatct gttacttcca tttcagtgat
     9841 gccaaagcgt tctttcattt gttcaccgta aacagtgttt gtatcatgga aagctggcaa
     9901 gcagtgcaag aagatcaaac gatctgtgtt gtgtgttttt tctaccattt ccatattgat
     9961 ttggtaaggt ttcaacaatt tgatacgttc ttcgaattta tcttcttcac ccattgatac
    10021 ccatacatca gaataaagga cgtctgctcc gtctacacct ttatcaacat cgtcggtaat
    10081 catcaattgt gcaccggatt tttcagcaaa gccttctgcc attttgacga tttcttcttc
    10141 aggttgtaat tcttttggtg caacgatacg catattcgct cctaaaattg cacctgtgac
    10201 taataaagag ttagccatat tgtttcgacc atctccgcag taagcaacag tgataccttc
    10261 tactgttcca aagttttctt ggatagttaa aaagtcagcg atcatttgtg ttggatgcca
    10321 ttcatcagtc aagccattcc aaactggaac accagagaat tctgctagtt cctctaccat
    10381 tttttgactg aatccacgga attcgattcc atcaaacata cgacctagta ctttagctgt
    10441 atcttctgtg gattcttttt tacctaattg gatatcattt gcacctagat attcaggatg
    10501 tgcacctaga tcgatcgctg cagtagtaaa tgcagaacga gtacgtgtag atgttttttc
    10561 aaataaaagc gcaatatttt ttccttctag atagtgatgt gggataccac gttttttcaa
    10621 gtctttcaag tgttctgaaa aatcgatcaa atattgtaat tcttcttttg taaagtcttt
    10681 ttctgctaat aagcttcttc cttggaatac tgattctttc atattaaaca ttctccttta
    10741 gattgttttt atttaagatt aaagaggaaa tcccgacggc agctgacagt aagaccgccg
    10801 tcaggaaaca aattacttca agtcttcacg gacaagtggt tggctcatgc agcgtggacc
    10861 accacggcct cgtgacaatt cacttgaatt gatttctaac actttgatgc catagctacg
    10921 aagcaattcg ttcgatacat aatttcggtt ataagtgact acaacacctg gagcgattgc
    10981 caatgtgttt gatccatcat tccattgttc tcgaggtgca acgatctcat ctccattacc
    11041 agttgggatc agtacaagat catctaatcc aagagcagct ttcatcgttt cgtgtaagtt
    11101 atctgaatga gtaatcttga tatcatcacc atctggttcg attgtaaaga catccatctt
    11161 accgtcttta ctttgaattg ctggatggat agtgaattta tcgtgatcta ccattgtaaa
    11221 tacggtatcc aaatgcatca ttgcacggtt gtttggaatt ttgattgcta acactttttc
    11281 aaatcctgaa ttttttgcga ataggtggcg tgctaatttt tctaaagctt tcgcattagt
    11341 tcgttgagaa atcccaacag ctactacttt atcgcttaag atcaattcgt ctccgccttc
    11401 gatatgatct ggattttcac gatccaacca tacttcgatt cctttatttg caaatcttgg
    11461 atgatgtttc aaaatatatt ctgtaaacat cgattcacga cgacgtgctt caaaagtcat
    11521 cttattgact gtcatcccat ttcccattga tgcggaaggg tcgcgtgtaa agtacaagtt
    11581 tggcattggg tccatgtaaa atggatagtc atcgtctgct gacagatcgt atagactgct
    11641 agaacgtact tcaatatctt ttgtacgaac cccagccatg attttatcta ccatttcttg
    11701 cgtttccatt gatagaagga actcatgaag accctctctt acagcattcg atgcaatatg
    11761 agattcatcc aacattttat tcaagaattg ttctttgaca ttgcctgcgt caatcgcttc
    11821 tgccgctaat ttttccaagt aaagagtctc gacgccttca ttttgcaatg tctttgcaaa
    11881 gttgtcatgt tcttcttgag caatcggaag atatggaata tcatcgaaca acagacgatc
    11941 cataatatct ggtgtcaaat tttccacttc ttgtccaggc cttttcagta aaactgtctt
    12001 taatttccct atttcagaga aaacgtgaat aggtttatcc atgttgtgtt gcctccttct
    12061 ttttgattac atgtatagga tatcctcctt ttgtaatcac tttcataatt ttgtctcatt
    12121 caaaatgaga cattcctcac attaatattc gataattaaa taattaaacg tttttctatt
    12181 tttaagcgta attta
//
LOCUS       DAZKKZ010000076        12163 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.078, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000076 DAZKKZ010000000
VERSION     DAZKKZ010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12163)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12163)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12163
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.078"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            158..730
                     /locus_tag="ACG8LA_002425"
     CDS             158..730
                     /locus_tag="ACG8LA_002425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003706982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HFQ0204702.1"
                     /translation="MTENKATQERTPQERLQEEQEHKEHVHHTKINAAAIADHLLGNM
                     HTLHVKLHQYHWYVKGANFFTLHEKFEELYNENEKWFDKLAERLITSGHKPASTTVEF
                     EKYSMLSEDAVNKYAKAEDMVENIIEDFRSTRDLTIRAIRLAQDEGDDALEDTLIAFK
                     NDLDKNIWMLQAFIGKEALEDDDALDEDED"
     gene            875..1579
                     /locus_tag="ACG8LA_002426"
     CDS             875..1579
                     /locus_tag="ACG8LA_002426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011476586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HFQ0204703.1"
                     /translation="MTKHTHHEIGDHAACIRLVPIFNHLEDSAMNYIAEKAHTKQYQK
                     GEFLFRSQEKEDTLYIINRGKIRIYRLADSGKEQLVRILNPGDFTGEWTLFNPDAVHE
                     EYAEATRDTVVCMIQQKDVQDFLEQYPAISLKLLAEMSKRLESSERQTTQVAVESVIT
                     RLVLFLAENVEPEMGNSPTITLPMAKKDIASYLGTTPETISRKFGELEDEGLIQQLSG
                     KRIKIQDLDDLLLYSE"
     gene            1807..2145
                     /locus_tag="ACG8LA_002427"
     CDS             1807..2145
                     /locus_tag="ACG8LA_002427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204704.1"
                     /translation="MHCFWVIVAITLSAAGAFFVVPFTKNTIGGEAKTSNVVEADRLA
                     MEKEEEVVKGAGVIGHGKVAYYEASDQGDKSVFTVWFPWSLAGILFSITMTRMTRKIE
                     EMEQIEWDSY"
     gene            2130..2984
                     /gene="lgt"
                     /locus_tag="ACG8LA_002428"
     CDS             2130..2984
                     /gene="lgt"
                     /locus_tag="ACG8LA_002428"
                     /EC_number="2.5.1.145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008961 -
                     phosphatidylglycerol-prolipoprotein diacylglyceryl
                     transferase activity [Evidence IEA];
                     GO_process: GO:0009249 - protein lipoylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HFQ0204705.1"
                     /translation="MGFVLGVLNPHVVEIGSVVIHWYGVIIAAGILAALQLSTKEAKK
                     KGLEEDTIIDMALWAIPIGLLGARLYYVLFELGYYLQNPGQILAIWNGGIAIYGGLIA
                     GGGTLYWYAKKKGTSLALVLDILAPNVLLAQSIGRWGNFMNQEAHGGPVTRQFLENLY
                     LPEFIIEQMNMNGTYYHPTFLYESLWSLLGFVLIVTIRNRKQLLRQGEVALSYVLWYS
                     VGRFFIEGMRTDSLWIGEWIRVSQALSLALFIGAIVVWFIRRQDYPPISYYSDGNKGQ
                     KKTIKMVN"
     gene            3131..3364
                     /locus_tag="ACG8LA_002429"
     CDS             3131..3364
                     /locus_tag="ACG8LA_002429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy-metal-associated domain-containing
                     protein"
                     /protein_id="HFQ0204706.1"
                     /translation="MEKAILQLETLSCPSCMQKIEGAVKSVNGIDKDSIKVLFNSSKV
                     KTNFDSAVTSIEEIQKAIENVGYPVLKAKVKAV"
     gene            3562..5466
                     /locus_tag="ACG8LA_002430"
     CDS             3562..5466
                     /locus_tag="ACG8LA_002430"
                     /EC_number="7.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015662 - P-type ion transporter activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0019829 - ATPase-coupled monoatomic cation
                     transmembrane transporter activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HFQ0204707.1"
                     /translation="MQQYILSKKNVITVISGLLIVLGFFSHFVLENVGLSEWSLIIAS
                     VFGITPIAIQAFQAMKVKVISIDVLVSIAAIGALFIQNYEESAIVTFLFLFGHYLEQR
                     TLNQTRSAIKELTEMAPESALKQMDNGEFEEVEVDDIDEGDILLVKTGAKVPVDGIVL
                     TGEGHINEASITGEAIPVNKLADAEVFAGTILENGTIQIRADRVGEDTTFGKIIELVE
                     EAQDSKSEAERFIDRFSKYYTPAVLVLAIVVWAFSQNIELAITILVLGCPGALVIGVP
                     VSNVAGIGNGARNGVLLKGSEVIQDFSNVDTIVFDKTGTLTVGNPTVAATELYEKDPA
                     ETLGYLASVERESDHPLAKAVLNQIGETNFYPVEGTEVVKGGGIVSSVAGHRVAVGNV
                     ALMEKENVTLSKKVQKDVKRFEQQGNSLVLTAVDGELKVLMGIRDQVRPGVKANLQEL
                     KDLGVKNLVVLSGDNQGTVDVVAGELGLTEAHGYMLPEDKSAYIGKLQQRGQIVAFVG
                     DGVNDSPSLALADIGIAMGSGTDVAIETSDVVLMNSNFSNLPHALGLVKATANNMKQN
                     IVISIGVVLVLLTSVFFSEWMNMSIGMLVHEGSILVVIFNGMRLMKYKLKGRKEQKEV
                     SAPAEKVKIS"
     gene            5776..6138
                     /locus_tag="ACG8LA_002431"
     CDS             5776..6138
                     /locus_tag="ACG8LA_002431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ArsR/SmtB family transcription factor"
                     /protein_id="HFQ0204708.1"
                     /translation="MEKVCQVTIVHKEKVNVIKKKLDQKDFSNLLVLGKCFSDSSRIK
                     IFYALETYKEMCVCDLAEILTASVATTSHHLRFLKKHGMAKSRQDGKVVYYSLANEDI
                     LSAIRVFLKLSENLSMKS"
     gene            6155..6766
                     /locus_tag="ACG8LA_002432"
     CDS             6155..6766
                     /locus_tag="ACG8LA_002432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HFQ0204709.1"
                     /translation="MLQSIFSAIAVYISTSIDYLFILLIIFSQSHTKKGIRHIFWGQY
                     LGTGILVAVSLFAAYVLNFIPQDWIIGLLGLIPIFLGIRVAFVGEEEEEEEEVVEKLE
                     SRGTNRLFWTVALITIASGGDNLGIYIPYFTSLAFSEIIIALIVFAISVAVLCYISYK
                     LAKISFVSETLEKYERIIVPIMFIALGIFIMIENGTIQTLLGF"
     gene            complement(6868..7776)
                     /locus_tag="ACG8LA_002433"
     CDS             complement(6868..7776)
                     /locus_tag="ACG8LA_002433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HFQ0204710.1"
                     /translation="MSKSDKDHNHSNQNQPKKNIKIAFFINLIFSISEFFFGFLFNSV
                     SIMSDAVHDLGDSISIGFAWFFQGYSEKKQDERFTFGYNRFSLLGALITGVVLISGSF
                     FMIYRSVPRLIDPQPVNYSGMFWLSLVAIALNGYAAWILSKGTSKNESMLNLHMLEDV
                     LGWIGVLIVSILMNFTEAYRLDPILSILIALYILYKTVPEFFTTMKILLNGSPENVNV
                     KSLADSIKNVPAVKDLSHFHIWSLDGEENALIITVLIDPSDIDKAREIKEEIAEVAHK
                     SSVENHITIEITTSKEELEKGYSHNT"
     gene            complement(7818..8132)
                     /locus_tag="ACG8LA_002434"
     CDS             complement(7818..8132)
                     /locus_tag="ACG8LA_002434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="HFQ0204711.1"
                     /translation="MDIKTTSPIDKGSILSISKLFKVISDPTRLSVLFLLQKKECSVG
                     NIAISLDMEQSAISHQLKTLKDARLVKSRREGKSMLYSLDDLHVFSILEQVLTHVNEL
                     EK"
     gene            8431..10362
                     /locus_tag="ACG8LA_002435"
     CDS             8431..10362
                     /locus_tag="ACG8LA_002435"
                     /EC_number="7.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015662 - P-type ion transporter activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0019829 - ATPase-coupled monoatomic cation
                     transmembrane transporter activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HFQ0204712.1"
                     /translation="METIQEQQSQEKHNHNHNHDHDHDHGKMPVVLYFVGLALAVIAL
                     FLNEDYQLVQNVLFSIATISAGYHVILLEGLGETIENSKAQKKFIPNSHILMGLAAIG
                     ASLMGNFWEGTLLILIFSGAHFLEDYAEGRSKREITKLLEMNPTTARLILPDGSTKNV
                     DVSELKVGDQLQVLNGDQVPIDGVILSGSTSIDESSITGESIPKEKSKGDGVFGSTIN
                     GTGTFTMKVTKENKDTVFSKILQLVNQNQDNQTKAASIIQKFEPKYVTVVLIAIPLFM
                     LLAPFLLDWTWSQSVYRGLVLLVAASPCALAAATVSATLSTTSNLAKKGVLSKGSSYL
                     SQLADIKAIAFDKTGTLTKGKPEVTNYYFADSVNEENMIDIVVALEKESNHPLADAIL
                     RKFEQKNKLTIEVENQIGKGLTGDYKGRNYRIGKPTSFDDVSDEYSRLNNEWASEGKT
                     VVYVAVDEEVIGLIALMDVPSEYAKETIEYFRKQGIHTTLITGDSEMTGKAVAKQLGI
                     DEVIANVMPEDKSRIIDEQKEKYGVTAMVGDGVNDAPALVNADVGIAMGDGTDVAVEV
                     SDLVLMQNNLSKLVQSHNISSKMNRVIWQNIIFSMAVVAFLIVVSFLGLTDIAISVII
                     HEGSTLVVILNGLRLLKAV"
     gene            10655..11206
                     /locus_tag="ACG8LA_002436"
     CDS             10655..11206
                     /locus_tag="ACG8LA_002436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFQ0204713.1"
                     /translation="MGYNVQPLRSQQEINDFLFCLRRNKNAERDVFLFLIGINSGLRM
                     SDIVKLKKKDVITSKNPRIVEQKTGKTRILYLSSLQDLIHGYTAPLDPEAYLFPSTKG
                     GHLEVNTVYQMFQKVAKLLGRDDIGTHTLRKTFGYHYYKKTKDVATLMEIFGHSSEKI
                     TKRYIGINEDEISETLLNFRLGF"
     gene            11519..12061
                     /locus_tag="ACG8LA_002437"
     CDS             11519..12061
                     /locus_tag="ACG8LA_002437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBECR4 domain-containing protein"
                     /protein_id="HFQ0204714.1"
                     /translation="MSIKETTQITRQLNAIYKAAHLLQEHFVDKKVSFVGEVSTVAII
                     FSTTNFMHLCGIDYRRGTHLFFQDALDRKINLQDIQIKTDGTTFQKLQVIGSLDLLLG
                     KHISIVGRGVYSSLRYDAAIRTRKKILALSLKQNGLIYIPISLLNLSSKEIGPGQKVT
                     GIFSEDLTSGELKMIMEVID"
BASE COUNT         3952 a         2034 c         2555 g         3622 t
ORIGIN      
        1 aatttaatag agaagcctgg cgtctattaa gaaataattt tcttgatgag cgtcaatttt
       61 tttaacggaa atctatccta tactaaattc agtaaagaaa aaggaggaat caaagaaagc
      121 tattttaaac aaaccaaaat tataggagga ataaatcatg actgaaaata aagctactca
      181 agaaagaaca ccccaagaaa gattgcaaga agaacaagaa cacaaggaac atgttcatca
      241 tacgaaaatt aatgcagcgg ccattgcgga tcatctttta ggcaacatgc atacattaca
      301 tgtgaaactg caccaatatc actggtatgt aaaaggagcc aatttcttta cgttgcatga
      361 aaaatttgaa gagttgtata acgaaaatga aaaatggttc gacaaacttg cggagcgtct
      421 aattacttct gggcataaac ctgcttcgac aacggttgaa tttgaaaaat attcgatgct
      481 ttcggaagat gcagttaata aatacgctaa agcagaagac atggttgaaa atattatcga
      541 ggacttcaga agcactcgtg acctaactat tcgcgcgatt cgtttagctc aagacgaggg
      601 tgacgatgct ttagaagata cattgattgc ttttaaaaat gacttagaca agaacatttg
      661 gatgctgcaa gcgttcattg gtaaagaagc attagaagat gatgacgctc ttgatgagga
      721 tgaagattaa ggtaaaagta gaagctgatt tagggattgg aattctttcc agtccttttt
      781 ccattttctt gatgtgcatc aatttttttg tagtaagaga cttatataat aaaagcagcg
      841 aatataaaca aaataaataa agggggagaa tgaattgact aaacataccc atcatgaaat
      901 tggcgaccac gcagcctgta tccgcttggt tccaatattc aatcacttag aggatagcgc
      961 gatgaattac attgctgaaa aagcccacac gaaacagtat caaaaaggag agtttctgtt
     1021 tcgttcacaa gaaaaagagg atactttata tattatcaat cgtgggaaaa tccgtattta
     1081 tcgattggca gactctggca aagagcagct agtgcggatc ttgaaccctg gtgatttcac
     1141 cggagaatgg accttgttca acccggatgc agtacacgag gaatatgccg aagcaacccg
     1201 agataccgtt gtctgtatga ttcagcaaaa agatgtccaa gattttctgg aacaataccc
     1261 agctatttct ttaaaactat tggcggaaat gtctaaacgg ttagaaagtt cagaacgtca
     1321 aacgacacaa gtagccgtgg agagtgtcat tacccgttta gttttgtttt tggcagaaaa
     1381 tgtggaacct gaaatgggca actctcccac catcaccctg ccgatggcaa aaaaggacat
     1441 tgcttcctat ttaggaacga cacctgagac catcagtcgc aaatttggag aattggagga
     1501 cgaaggattg attcaacagc tgtctgggaa aaggatcaag attcaggatt tagatgattt
     1561 attgctttac agcgaataat cggacacact tttttctaca cgttggtgtt ctgtcgctct
     1621 tcattaacaa cgggacagaa ctcagtgctt ttgcttccat ctgtccgttt ttggcttttt
     1681 taagacagaa cgaccttcat tcattggaaa aataaaagca caaacatgat aaccctcaag
     1741 tttttttgtt ttatttttct ttaagatagg gttgtcgaac aaaacgtaaa aataagtagg
     1801 gtgaatgtgc attgtttttg ggtgatagtt gccatcacgt tgtcagcagc gggggcattc
     1861 tttgtcgtcc ctttcaccaa gaacacgatt ggcggcgaag caaaaacgtc taacgttgtt
     1921 gaggcagata ggttagctat ggaaaaagaa gaggaagttg taaaaggagc cggcgtaatc
     1981 ggacacggaa aagtggcgta ttacgaagcg agtgaccagg gagataaaag tgtattcact
     2041 gtttggtttc catggagctt agccggaatc ttgttcagca tcaccatgac tagaatgacg
     2101 cgaaaaattg aagaaatgga gcaaatagaa tgggattcgt attaggcgtt ttgaatcccc
     2161 atgtggtgga gattggttct gttgtgattc attggtatgg agtcattatt gcagcgggca
     2221 tattagcggc tctccagttg agcaccaagg aagcaaagaa aaaaggactg gaagaggata
     2281 ccattatcga tatggcctta tgggcaattc cgattggact cctcggcgct cggctttatt
     2341 atgtgttatt tgaacttggt tattatctgc aaaatccagg acaaatcctt gcgatttgga
     2401 atggcggcat tgcgatttat gggggattga ttgcaggagg gggtacgcta tattggtatg
     2461 caaagaaaaa aggtacttct ttggcactcg ttcttgatat tttagcgccc aatgtattgt
     2521 tagcccagtc cattggtcgt tggggcaatt ttatgaatca ggaagctcat ggtgggccgg
     2581 ttactcgtca attcttggaa aatctttatt tacctgaatt tatcattgaa caaatgaata
     2641 tgaatggtac ctactaccat ccgacttttt tatacgagtc attgtggagt ttgttgggct
     2701 ttgtcctcat cgtcactata cggaaccgaa aacagctttt gcgtcaagga gaagtcgctt
     2761 tgagttacgt tttgtggtac tcagtgggtc ggttcttcat tgaaggtatg cgaacggaca
     2821 gtttatggat tggcgagtgg atccgcgttt cgcaagcctt gtctctggcc ctgtttattg
     2881 gcgcgattgt agtatggttt atacgcagac aagattatcc accaatttct tattattctg
     2941 atggcaataa ggggcagaaa aagactatta agatggtgaa ttgagcaaaa agataaaaag
     3001 aagtgcaaaa cttgatatgc gtcaattttc gtttgctaaa agtgagctat actacagttg
     3061 taaagaggaa aaggcagtgt tcattaatct gctgccgata aaataaaaac acataaagga
     3121 gataggaatt atggaaaaag ctatattgca attagaaacg ttgtcttgtc caagttgtat
     3181 gcaaaaaatt gaaggtgccg tgaaatcagt taacggtatt gataaagaca gcattaaagt
     3241 attattcaac tccagcaaag tcaaaaccaa ttttgattca gctgtcactt cgattgaaga
     3301 gattcaaaaa gctatcgaaa acgtaggcta tccggttctt aaagcaaaag tcaaggccgt
     3361 ttaacagatt aaatgaacta ggcaattctg gaagaaaagc tatttttcca ggattgcttt
     3421 ttttgttgca atccgattcg aggtgcttag aaacgataaa agagaacttt ctaaacttga
     3481 tgtcagtcaa ttaattactt aggcaattat cttatactgt gtttatcaat aaaagagaaa
     3541 ttaaatttgg agggaaaaag catgcaacaa tatatattaa gcaagaaaaa tgttatcacc
     3601 gtcatcagtg gattgttaat cgtactcggt ttcttcagtc actttgtttt agaaaacgta
     3661 ggactttcag agtggtcttt gatcatcgcc tctgtctttg ggattacgcc aattgccatt
     3721 caagcgtttc aagcaatgaa agtcaaagtc atcagtattg atgtcttagt cagtattgca
     3781 gcgattggtg cgctttttat tcaaaattat gaagaatcgg ctattgtcac gttcttattc
     3841 ttattcggac actacttgga acaacgaaca ttgaaccaaa cgcgatctgc tatcaaagaa
     3901 ttgactgaaa tggcacccga aagcgccttg aaacaaatgg ataatggcga atttgaagaa
     3961 gtagaagtgg atgatataga tgaaggggat atcttgctcg ttaaaacggg tgcgaaagtt
     4021 ccagtagatg gcatagtcct tacgggtgaa gggcatatca atgaagctag cattacaggt
     4081 gaagctattc cggtcaacaa gctagctgat gcagaagttt ttgcaggaac cattttagaa
     4141 aacggaacga ttcaaatcag agctgaccga gttggtgagg acaccacatt tggaaaaatt
     4201 attgaactcg tggaagaagc acaagattct aaatccgaag cggaacggtt cattgatcgc
     4261 ttttctaaat actacacacc agctgtcttg gttctggcaa ttgttgtatg ggcgttcagt
     4321 caaaatattg agttagcaat caccatcttg gttctaggtt gcccaggcgc attagttatc
     4381 ggagtgcctg tctcaaacgt tgccggtatt gggaatggtg ctcgtaacgg tgttctttta
     4441 aaagggagtg aagtcattca agacttcagt aatgtggata caattgtatt tgataagaca
     4501 ggtactttaa ctgtcggaaa cccaaccgtt gcagcgactg aactgtatga aaaagatcct
     4561 gctgaaacgc ttggctatct ggccagtgtg gaacgggaat cagatcatcc attagcaaaa
     4621 gcggtcttaa atcaaattgg agaaacaaac ttttatcctg ttgaaggaac tgaagttgtg
     4681 aaaggcggcg gaatcgtttc aagtgtagct ggacatagag tggctgttgg gaatgtggcc
     4741 ttgatggaaa aagaaaatgt cactctcagc aaaaaagtgc aaaaagatgt caaacggttt
     4801 gaacaacaag ggaactctct cgttttgaca gcggtcgacg gtgaattaaa agtactgatg
     4861 ggcattcgcg atcaagtccg tccgggtgtg aaagctaatt tgcaggaatt aaaagacttg
     4921 ggcgtgaaaa atctagtcgt tctttcagga gataaccaag gaaccgttga tgtggtcgcc
     4981 ggcgaacttg gtttgaccga agctcacggc tacatgttgc cggaagacaa atcggcttat
     5041 atcggaaaac ttcaacaacg tggtcaaatt gtagcctttg ttggagatgg cgttaacgat
     5101 agtccgtcct tagctttagc agacattgga atcgcaatgg gaagcggaac ggacgtagcg
     5161 attgaaacat ccgatgtcgt tttaatgaac tcgaacttca gcaacttgcc tcacgcatta
     5221 ggattagtaa aagccaccgc aaataatatg aaacaaaata tcgtgatttc aattggagta
     5281 gtgttggtct tgttgaccag cgtcttcttc agcgaatgga tgaatatgtc tatcggaatg
     5341 ttggttcatg aaggtagtat cttggtggta attttcaatg gcatgagatt aatgaagtat
     5401 aagttgaaag gtcgaaaaga acaaaaagaa gtatcagcac ctgcagagaa agtaaaaata
     5461 tcttaagaat aaattagaag aggctgagac aatagtccat ccttgaaatg acaaaagcgg
     5521 aaactcagat ttttaaatct gggattttcc gcttttttga gttcttgaaa aaaaataaga
     5581 gtatagagta tgttctttat aaaattaatt ttcgtgtaaa tgattaaaaa atttaataat
     5641 aaaatttaaa ttcctattaa gttgtaacac atgaaattgc ttataatagt gtattgaaat
     5701 taaggtagat tgacaaacga gtgatcaaat agatatacta ccttcaaacg accgtttgaa
     5761 tgtgaggtga gatgaatgga aaaagtttgc caagtgacta tcgtacataa agaaaaagta
     5821 aatgtaataa aaaaaaaatt ggatcaaaaa gatttttcaa acttacttgt gttagggaaa
     5881 tgtttcagcg attcttctag gattaaaatt ttctatgctt tagaaaccta taaggaaatg
     5941 tgtgtctgtg atttagcaga aatacttact gctagtgtcg ctacaacgtc acaccattta
     6001 cgttttttaa aaaaacatgg aatggcaaaa tcacgtcaag atggaaaagt agtttattat
     6061 tctttagcga atgaagacat cctttccgct attcgtgttt ttttaaagtt atcagaaaat
     6121 ctatctatga aatcttagtt tggaggaagt tattttgtta caaagtattt tttcagctat
     6181 cgctgtttat atttctacca gtattgatta tttgtttatc ttgctgatta tcttttctca
     6241 aagccacaca aaaaaaggta ttcgtcacat tttttggggt caatatcttg gaacaggtat
     6301 tttggtagcc gtaagtttgt ttgctgctta tgtgctaaat tttattccgc aagattggat
     6361 cattggtctt ctcggtctaa ttccgatttt cttaggaatc agagtcgctt ttgttggcga
     6421 agaggaggaa gaagaagagg aagtcgttga aaaactcgaa tctagaggaa ctaatcgctt
     6481 attctggaca gttgccttaa taacgattgc ttctggaggc gataatttag gtatttatat
     6541 tccatacttt acctcgttag ctttttcaga aatcattatt gctttaatcg tattcgctat
     6601 ctctgttgcg gttctctgct atatcagtta caaattagcc aagatttctt ttgtttccga
     6661 aacgttagaa aaatacgaac gaatcattgt ccctataatg tttattgcgt taggaatttt
     6721 tattatgata gagaacggga cgatacaaac gctactaggt ttttaaaaat cataatcacg
     6781 aaagataaaa agagaggcag cgactaatca aaatcgctgc cttttttgct tttcaaataa
     6841 tgaagtattt tttagcgtag aactatctta cgtgttgtgg gagtatccct tttcaagctc
     6901 ttctttgctt gtagttattt ctattgtgat atgattctct acgcttgatt tgtgtgcgac
     6961 ttctgcaatt tcttctttta tttccctagc cttgtctatg tctgaagggt ctataagaac
     7021 cgtgatgata agggcgtttt cttccccgtc cagtgaccaa atgtgaaaat gtgagaggtc
     7081 ttttacagca ggaacatttt taatggagtc cgccaagctc tttacgttta cattttcagg
     7141 cgaaccattc aataaaattt tcattgtggt gaaaaattca ggaacggttt tgtagaggat
     7201 ataaagtgca atcaaaatcg ataagatagg atccagacga tatgcctcgg taaagttcat
     7261 tagaatactc acaatcaaga ctccaatcca ccctaatacg tcttccagca tatggaggtt
     7321 caacatgctc tcgtttttgg atgtgccttt gcttaaaatc cacgcagcat atccattcaa
     7381 tgcaatagct acgagagaaa gccagaacat gccactataa tttacgggtt gtgggtcaat
     7441 caaacgtggc acactacgat agatcataaa aaacgagcca ctaattagca caacgccagt
     7501 tatcagcgcg cccagtaaag aaaagcggtt atagccaaaa gtgaaccgtt catcttgttt
     7561 tttctctgaa taaccttgaa aaaaccaagc gaatccaatt gaaatagagt cccctaaatc
     7621 atgaactgcg tcggacataa tggacacact attgaaaaga aagccaaaga aaaattcgct
     7681 tatagagaaa ataagattta tgaagaaagc aattttaata ttctttttcg gttgattctg
     7741 attcgagtga ttatggtctt tatctgattt tgacatttaa aaacctccta agtttgtatg
     7801 ctacatacta attggtttta tttttctaat tcattaacat gagttaagac ttgttcgaga
     7861 atactaaaaa catgaaggtc atctaaactg taaagcatac tttttccttc tcttcttgat
     7921 ttcactaagc gtgcgtcttt caacgttttt aattgatgag aaatagcgga ctgttccatg
     7981 tccagagaaa tagcgatatt tccaacacta cactcttttt tctgtaaaag aaagagaacc
     8041 gacaatcgtg taggatcact aatcacctta aatagtttgc ttattgacag aatagatcct
     8101 ttatcgattg gagaagttgt ttttatatcc atagtgtttt tattcctttc atatgacctt
     8161 ccgttcatat ctatattacc atatgagcga aacaatgcta atcttttgtt tataaaagag
     8221 aagtggcgtt ctctttatct tgacaaaatg tatatagcga tataaaatga gtatacaaac
     8281 atatgattaa ttagtcatat gtaaggtgga ttcattacga tttacttttg gaataaacga
     8341 aaggagtcag aaatagcaga aatttatgtg attcaagaag taaatgatgg aaaacaaagg
     8401 aattataaat tatataggga ggcaatagaa gtggaaacta tccaagaaca acagtctcaa
     8461 gaaaagcata atcataatca caaccacgat cacgaccatg atcatgggaa aatgccagtc
     8521 gttttgtact ttgttggttt agcattagca gtgattgctc tatttttgaa tgaagattat
     8581 cagttggtac aaaatgtttt gttctcaatc gctacaatca gtgccgggta tcacgttatt
     8641 cttcttgaag gccttggaga aacaattgag aattcaaaag cacaaaaaaa gttcatacct
     8701 aattctcata ttttaatggg attagcggca attggagctt ctttgatggg gaatttttgg
     8761 gaaggaacat tattgattct tattttttct ggcgcacatt ttttggaaga ttatgcagaa
     8821 ggaagaagca aacgagaaat aacgaaatta ctcgaaatga atccaacgac tgcccggtta
     8881 atcctgcctg atggtagtac aaaaaatgtg gatgtcagtg aattaaaagt gggagatcaa
     8941 cttcaagtgt tgaatggcga tcaagtacct attgatggcg tcattttgtc tggatctaca
     9001 tccattgatg agtcgtctat tactggagaa agtatcccga aagagaaatc caaaggagat
     9061 ggcgtcttcg ggagtacaat caatggaaca ggtaccttca cgatgaaagt caccaaagaa
     9121 aacaaagata cagtattttc aaaaatttta caattagtga atcagaacca agataaccaa
     9181 acaaaagctg cgagtattat ccaaaaattt gaaccgaaat atgtcacagt tgttttaatt
     9241 gccattcctc tattcatgtt attggctcct tttctacttg attggacatg gtcacaaagt
     9301 gtctatagag gattggtcct tttagttgca gcttcaccgt gtgctttagc agcagctact
     9361 gtctcggcaa cgctatcgac gacttctaat ttagccaaaa aaggagtcct ttcaaaaggt
     9421 agttcttacc tgtctcaatt agccgatatt aaagcaattg catttgataa gacgggcacc
     9481 ttgaccaaag gaaaacctga agtaaccaat tattattttg ctgattccgt gaacgaagaa
     9541 aacatgattg atatcgtagt agctcttgaa aaagaatcca atcacccctt agcagatgct
     9601 attctaagaa agtttgagca aaaaaacaaa ctaactattg aagtagaaaa ccaaattggt
     9661 aaaggattga cgggagatta caaagggaga aattatcgta taggaaaacc gacttcgttt
     9721 gatgatgttt cagatgaata tagtcgttta aataatgaat gggcgtcaga aggtaagaca
     9781 gtcgtatacg tagcagtaga tgaagaggtt ataggcctta ttgcccttat ggacgttccg
     9841 agtgaatatg ctaaagaaac cattgaatat tttaggaaac aaggtataca caccacatta
     9901 attactggtg actcagaaat gacgggaaaa gcggttgcta aacaattagg aatagatgaa
     9961 gtgattgcga atgtcatgcc ggaagacaaa tccagaatta tagacgaaca aaaagaaaaa
    10021 tacggcgtga ccgccatggt tggagacggt gtaaatgatg ctcctgctct tgttaatgca
    10081 gatgtgggaa tcgctatggg agatgggact gatgtggcag tagaggtatc tgatttagtt
    10141 ttaatgcaaa acaatttatc taaattggta caatctcata atatttcttc gaaaatgaac
    10201 cgtgttattt ggcagaatat tattttttca atggccgttg ttgctttttt aattgtcgtt
    10261 agtttcttag gcttaacgga tattgcaatc agtgtcatta ttcatgaagg aagtactttg
    10321 gttgttattt tgaatggact tcgattgcta aaggcagtct aaagaatgat tgcacaactt
    10381 caaattaatc gagtaataga gataattaag gattacacta cattttttat ctctattact
    10441 tgtttatatt tatctagatg ttcaaagtca aaatgatata tcaaccatac tcttgtggcg
    10501 cgggttgaat ataagataca tgaaattgga taaaatcatg tatcaagaat cctatcctta
    10561 tagggttctt tttttttact ccccctaaac acacgatttc gtgttgtaat aactataatc
    10621 atgtattcga acagactaaa aaggagggat tgtcatgggc tataatgttc agccactacg
    10681 gtcgcaacag gagattaatg attttttatt ttgcctgcga cggaataaaa atgcggaacg
    10741 tgacgttttc ttgtttctaa ttggaattaa cagcggtctg cgcatgtccg acatcgttaa
    10801 actcaagaaa aaagacgtga ttacctcaaa aaacccgcgc atcgtggagc aaaagacagg
    10861 gaaaacacgc attttatact taagcagctt acaggacttg attcacggct ataccgcacc
    10921 cttagatccg gaggcttact tgtttcccag tactaagggc ggccatttag aagtcaatac
    10981 ggtctaccag atgtttcaaa aggtcgcgaa gctgttagga agggacgata tcggcaccca
    11041 caccctacga aaaacctttg gttaccacta ttacaagaaa accaaagacg tggccacctt
    11101 aatggaaatc tttggtcaca gcagcgagaa gattaccaaa cgctacatcg gaattaatga
    11161 agatgaaatc agtgaaacgt tattaaattt tcggttaggt ttttgattgt attatataat
    11221 agataagcac agtaagacgg ttataatcac ccacagtatt ggacaaatca accttttttt
    11281 ggtatattat atatacaaat gagagcaggc tcatagtcaa cttgatataa atccggaaca
    11341 taagggtccg gcgggtggcg agcaccaaaa ctaaactcga tacaaatccg gaacgtaagg
    11401 gtccggcggg tggcaagcac caaaactaaa cctgtacaaa aggctgctct tttgagcagc
    11461 tttttttatt gggaaaaagg agcattcttc gcacgcggca aaaaaagaat acaaacgcat
    11521 gtctataaaa gagacaaccc aaattaccag acagttaaac gcgatttata aggctgctca
    11581 tctcttacaa gaacattttg tagataaaaa agtatccttt gtcggagaag tctcaacggt
    11641 agcgattatt ttttcgacaa ctaattttat gcacctctgt ggcattgatt atcgcagagg
    11701 cacacacttg ttttttcaag atgccttaga caggaaaata aatttacagg atattcaaat
    11761 caaaacggat gggacgacct ttcagaaatt acaagtaata ggtagccttg atttattatt
    11821 ggggaagcat atttctattg ttggcagagg tgtttactct tctcttcgct atgatgcagc
    11881 tattcgaaca aggaaaaaaa tattggctct gtctttgaaa caaaacggat taatctatat
    11941 ccctatctct ttgttaaacc tatcatcaaa ggaaattgga cctggacaaa aagttactgg
    12001 catttttagc gaggatttaa catccgggga acttaaaatg attatggaag tcatcgatta
    12061 atcattaata gtgatatgcg acgtcatttt gaagtaatta ttctattttg ggttataaaa
    12121 taaagcattt taagacgatt tcaaatcatt catgtgggtt att
//
LOCUS       DAZKKZ010000077        11602 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.079, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000077 DAZKKZ010000000
VERSION     DAZKKZ010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11602)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11602)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11602
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.079"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            5..1459
                     /locus_tag="ACG8LA_002438"
     CDS             5..1459
                     /locus_tag="ACG8LA_002438"
                     /EC_number="1.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0018478 - malonate-semialdehyde
                     dehydrogenase (acetylating) activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-acylating methylmalonate-semialdehyde
                     dehydrogenase"
                     /protein_id="HFQ0204715.1"
                     /translation="MTRFLRNYIDGRWVASRSTEFEEVMNPATEEALANVPLSSKAET
                     AEAVKAADAAFQTWKKVPVPVRGRYLFKLHQLLTDHKSELARLITLENGKSLSESLGE
                     VQRGIENVEHAAGITNLMMGDSLSTAATDIEITNYRYPIGVIGGITPFNFPMMVPFWI
                     FPMALAAGNTVVLKPSEKTPLLMEKIVELVEKAGFPSGVFNVVYGAHDVVNTLLQDPL
                     VKGISFVGSKNVGEYVYREGTKNLKRVQALTGAKNHVVVLKDANIDRAVKDLIGGAFG
                     SAGERCMAASVIVLEEEIADQFVEKFKAAAKAIKIGNGLDEGVFLGPVIRKDAQQRTF
                     DYIQKGVDEGAKLVLDGRENIPEKGYFVGPTIFDNVTMDMKIWQDEIFAPVASIVRVK
                     DLMAAVELTNESEFANGSCLYTNNASAIRYFRENVDAGMLGVNLGVPAPMAWFAFSGW
                     KHSFFGDLHANGKDSVEFYTHRKVVTARYAQSEI"
     gene            1535..2695
                     /locus_tag="ACG8LA_002439"
     CDS             1535..2695
                     /locus_tag="ACG8LA_002439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HFQ0204716.1"
                     /translation="MNIQLKMPANLRIGGGTIQFLMEESEQLGNKPLIISDTVMEQTG
                     HLQKIKELLGKTDDQLAEYTDIQAEPTQENVYDALKLFQKHQCDHIIAFGGGSCLDTA
                     KVVAVLAANQLSLEAIHARNFDQLQAGIPLIAVSTTAGTGSEVTDVAVITNTKTAVKM
                     MMKDLVFMPQISIVDSDFTKTVPPKVTAATGVDALCHALESYVSVKANEVTQLFSLEA
                     MKKILNTLSQAYENSDDTEAREQMSLASTEAGIAFSNASVTLIHGMSRPVGALFHIPH
                     GISNAMLLPVFFEFSKDAIQTELATIARFIYPAAEDLSLEEAADYLIKKIQELCEQLS
                     IPTIRDYGIDQQAFMAALDKMAADALTSGSPQNNKKVPSHSQIKELYVQAYG"
     gene            2808..3815
                     /locus_tag="ACG8LA_002440"
     CDS             2808..3815
                     /locus_tag="ACG8LA_002440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016634067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFQ0204717.1"
                     /translation="MRVKVGVIGTGAIGIEHIDRINQKTQGAYVTAVSDINVKAAKEV
                     AKRVDAKFFETGEALIASEDVDVVVVTSWDPTHEQYVLEAIKHGKYVFCEKPLAMDAA
                     GCRRIVDAEVAYGKKLVQVGFMRRYDRGYIELKEAIESKQYGEALMMHCAHRNPSADE
                     NYTTPMAISNTAIHEIDVLRWLLNEDYESVQMILPKKTSNSHADLHDPQLLIFQTKSG
                     VTIDLEIFVNCRFGYDIKCDVVFETAEVGMTDPAYTRIKSEEKNYTPVSPDWQTRFLD
                     AYDYEFKLWIDSIKNDAVVGPTAWDGYVAAITMMACHESRETKTKVMIQMDERPALYN
                     E"
     gene            3839..4864
                     /gene="iolG"
                     /locus_tag="ACG8LA_002441"
     CDS             3839..4864
                     /gene="iolG"
                     /locus_tag="ACG8LA_002441"
                     /EC_number="1.1.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050112 - inositol 2-dehydrogenase (NAD+)
                     activity [Evidence IEA];
                     GO_process: GO:0019310 - inositol catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="inositol 2-dehydrogenase"
                     /protein_id="HFQ0204718.1"
                     /translation="MNNIRVGIVGLGRLGKVHAQNLATGVSCCELTAACSLVETELAF
                     AQKKLGVKHTFSSYEEMVKSSVIDAVFIVSPSGFHCDQVRLAMENGKHVFTEKPLGLE
                     VEDIKKTQKVIEEHPEQVFMLGFMRRYDESYQYAKKMVEDGEIGEITLIRCYGIDPSE
                     GLESFVKFAMNNDSGGLFLDMAIHDIDLVRWFTGQEVDQVWAIGKNAAYPELDQAGEL
                     ETGAAMMSLSDKTIALLVAGRNAAHGYHVETEIMGTKGMLRVAQAPEKNLVTIMNDQG
                     IIRPCSQNFPERFREAFIREAQEFVSCIQEKRQPAVNAEDGLQSTKIALACQESFDTK
                     SLVQLKK"
     gene            4881..5771
                     /gene="iolE"
                     /locus_tag="ACG8LA_002442"
     CDS             4881..5771
                     /gene="iolE"
                     /locus_tag="ACG8LA_002442"
                     /EC_number="4.2.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010777829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050114 - myo-inosose-2 dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0019310 - inositol catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="myo-inosose-2 dehydratase"
                     /protein_id="HFQ0204719.1"
                     /translation="MTKQIQLAIAPIAWTNDDMPELGSENTFEQCISEMALAGFTGTE
                     IGNKYPKDPEVLEQYLNIRGLKVASAWFSAFLTTKPFEETAEAFKAHRDFLHAMGAKV
                     IVVAEQGHSIQGIMTAPVFDDKPVFTDEEWKKLAEGLEKLGDLAHEKDMEIVYHHHMG
                     TGVQTTEEIDRLMEMTDPDKVKLLFDTGHLVFSGENPIAVYNRHQDRIKHIHFKDIRQ
                     ETAEEVEKEKDSFLNGVKKGVFTVPGDGMIDFTPIWTAIHASDYEGWIVVEAEQDPAK
                     ANPFEYAVKARSYIREVTGL"
     gene            5794..7389
                     /locus_tag="ACG8LA_002443"
     CDS             5794..7389
                     /locus_tag="ACG8LA_002443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="solute:sodium symporter family transporter"
                     /protein_id="HFQ0204720.1"
                     /translation="MNLFSIISFLVIVICVWLFAYSRSRSVDTSGSEGFFMGGRSLTA
                     LPIAGTIIMTNLSTEQIVGQNGQSYHAGMEVMAWEVTATIAIVALAVIFLPKYFKYGI
                     NTISDFIEIRYDTVTKRIISILFIVTYMTSFLPVVLYSGSLVFNKIFHIDELLGVQPI
                     VAIIIVAMAIGIVGILYLLIGGLSLSANSDSIYGVGLLACGLLVPILGLMKLGDGSFV
                     GGIEHVVVNTPWLLNSVGSIDSAVVPWPTLFTGMLFNNLYFWCTNQMIVQKALSGKNL
                     AEAQKGAFLVGVFKILGALFLVFPGIVARNIFGDSLMSNPDNAYPFLVSEVLPKMIFG
                     IFAAVIFGAILSSFAGALNATSTLFSLDFYKPLINKKANDKQIARAGKTVTVVVGIIS
                     IIVAPFISFAPAGLYQFVQEFNGLYNMPLLVIILFAFYSKKATAFGAKTTIAVHIVLY
                     ALSKMLFQNIHFLYVLTALFVLDIIILMVVSKLKPDGEFVLNSFDTKVDIEPWKYTKV
                     TAIALVVIVILTYVAFSPIGFAG"
     gene            7405..7719
                     /locus_tag="ACG8LA_002444"
     CDS             7405..7719
                     /locus_tag="ACG8LA_002444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HFQ0204721.1"
                     /translation="MHKDLLIICETGISASLLVSKMLETIRAKNLSYEIDYATIRNVE
                     EKLNYKDYDVLLLTPQVARSEEKVKEIIKKEKCTAQIVYIKQEDFRYMNIENIIASIE
                     ED"
     gene            8180..8905
                     /locus_tag="ACG8LA_002445"
     CDS             8180..8905
                     /locus_tag="ACG8LA_002445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HFQ0204722.1"
                     /translation="MLEVKKLNVCYNDFLALNEISLKIQEGALTGIIGPNGAGKSTLL
                     KAMLNIIPHQGEVSINNEDINKKLVKIAYVEQKADIDFTFPIKVKECVSMGTYAGMKV
                     FQRIKNAEWQRVSKALEKVDMGKYSNHQIGELSGGQFQRVLLARCLAQNADFIFLDEP
                     FVGIDLVSERIIMDTLKELKHQGKTVLIVHHDLSKVKKYFDNIILLNRNLIAHGSVES
                     VFNEENLKKAYGDTIFIGEGGTA"
     gene            9038..9880
                     /locus_tag="ACG8LA_002446"
     CDS             9038..9880
                     /locus_tag="ACG8LA_002446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease subunit"
                     /protein_id="HFQ0204723.1"
                     /translation="MLQNFINGLYDFHFLQNALITSVVIGIVSGTVGCFIILRGMSLM
                     GDAISHAVLPGVAISYILGINFFIGAIVFGLLASIIITFIKSNSVIKGDTAIGITFSS
                     FLALGVILIGVANSSTDLFHILFGNILAVQDIDKWITIGVSVLVLVTVVLFFKELLIT
                     SFDPLMAKAMGMNVSFYHYLLMILLTLVAVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKTMIFISATVGACSSLLGLFIGYSFNIAAGSSIVLTAAFLFVISFLISPKQKFLRKK
                     ERKL"
     gene            9877..10827
                     /locus_tag="ACG8LA_002447"
     CDS             9877..10827
                     /locus_tag="ACG8LA_002447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein"
                     /protein_id="HFQ0204724.1"
                     /translation="MMRKWKAVLGSLGILIALFIFGACSTNSKDKDTVASNEKLKVVV
                     TNSILADITENIAKDKIDLHSIVPIGKDPHEYEPLPEDVQKTSKADLIFYNGVNLETG
                     GNAWFTKLVKNANKEENKDYFAASDGIDVIYLEGQSEKGKEDPHAWLNLENGIIYAKN
                     IEKQLAEKDPDNKKFYKENLDKYIEKLDSLDKEAKSKFASIPNDKKMIVTSEGCFKYF
                     SKAYNVPSAYIWEINTEEEGTPDQIKHLVEKLRTTKVPSLFVESSVDDRPMKTVSKDT
                     NIPIYSTIFTDSIAEKGQDGDSYYAMMKWNLDKIAEGLSK"
     gene            10842..11072
                     /locus_tag="ACG8LA_002448"
     CDS             10842..11072
                     /locus_tag="ACG8LA_002448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010708749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HFQ0204725.1"
                     /translation="MVQIKTTTILIYLLAIQELSKRKKKLKNNDLAKVLSVSPASVSE
                     MLTKLRYEDYLDIGFQLTDKGKKFIDDYKKRF"
     gene            11407..>11602
                     /locus_tag="ACG8LA_002449"
     CDS             11407..>11602
                     /locus_tag="ACG8LA_002449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFQ0204726.1"
                     /translation="MESGLSHFEKVGFQQTKIRQLCLTAGVTTGAFYKHFTSKEALFE
                     EIIQPHINALINMYNEEFTKY"
BASE COUNT         3682 a         1964 c         2597 g         3359 t
ORIGIN      
        1 ataaatgaca agatttttaa gaaattatat tgatggtcgt tgggtcgcta gtcgctcaac
       61 agagtttgaa gaagtaatga atccggctac agaagaagcg ctggcgaatg taccgttgtc
      121 tagcaaagca gagacagccg aagcagttaa agctgccgat gctgcgtttc aaacttggaa
      181 aaaagttcct gttcctgttc gcggacgtta tctgttcaag ctgcatcagc ttttaacaga
      241 tcataaaagt gaattggcgc gtttgatcac gctggaaaat gggaaatcat tgtccgagtc
      301 actgggagaa gttcaacgag gaatcgaaaa tgtggagcac gcagcgggaa tcaccaattt
      361 aatgatggga gattctttat caacagcggc gactgatatt gagatcacga attatcgtta
      421 cccaatcgga gtaatcggag ggatcacacc gtttaatttt ccaatgatgg tgcccttctg
      481 gatcttcccg atggctctgg cggcaggaaa tacggtggtg ctgaagcctt cagaaaaaac
      541 accattgttg atggagaaaa ttgttgagct ggttgaaaaa gcaggctttc ctagcggtgt
      601 ttttaatgtt gtctatggtg cccacgatgt tgtcaacaca ttgctgcaag atccactggt
      661 aaaaggcatc agctttgtag gatcaaaaaa tgtcggtgaa tacgtttacc gtgaaggaac
      721 aaaaaatcta aaacgggtac aagcgttgac tggagcgaaa aatcatgttg ttgtgctgaa
      781 agatgccaat attgatcggg cagtcaagga ccttattggc ggagcttttg gttctgctgg
      841 tgaacgctgc atggcagcct ccgtcattgt tttggaagag gaaatcgcgg atcagtttgt
      901 tgaaaaattt aaggctgcgg caaaagcgat caagatcggc aatggcttgg acgaaggggt
      961 ctttttagga ccagtgattc gaaaagatgc acagcagcgg acctttgact atatccaaaa
     1021 aggggtcgat gaaggagcga aactggtact agatggtcgc gaaaacattc cagaaaaagg
     1081 ctattttgtt ggaccaacga tttttgataa tgtcacgatg gatatgaaga tctggcagga
     1141 tgagattttt gccccggtcg catcaatcgt gcgggtaaaa gatttgatgg cagccgttga
     1201 gctgacgaat gaatctgaat ttgcgaatgg ttcgtgtctg tataccaaca acgcatcagc
     1261 gattcgctac ttcagagaaa atgttgatgc tgggatgctg ggggtcaatc ttggggtgcc
     1321 tgcaccgatg gcttggtttg ccttttcagg ctggaagcac tctttctttg gtgatttgca
     1381 tgccaatggc aaagacagtg ttgagtttta tacccatcgg aaagttgtta cagcacgtta
     1441 tgcgcaaagt gagatttaaa gatttgcttc gaagctctgt taaagagctt cgaggattct
     1501 gttataggct ataagccaga gagaggtttt ttctgtgaat attcaactga aaatgcctgc
     1561 caatttaaga attggcggcg gaacaatcca atttcttatg gaagaatcag aacaactagg
     1621 caacaagccg ttaatcatta gtgatacggt tatggaacag accgggcatc ttcaaaagat
     1681 caaggagctg ttgggaaaaa cagatgatca attagcggag tatacagaca ttcaagccga
     1741 accgacgcaa gaaaatgttt atgatgcgct gaagcttttt cagaagcatc aatgtgatca
     1801 tatcattgct tttggtggcg gcagctgtct ggatacagcc aaggtggtag ccgttttggc
     1861 tgctaatcaa ttaagtctcg aagcgattca tgcaagaaat tttgatcagc tgcaagcggg
     1921 cattccgctg attgcagtgt caacaactgc tggaactggt tcggaagtaa ccgatgtggc
     1981 agttattacc aatacaaaaa cagcagtcaa aatgatgatg aaggatctcg ttttcatgcc
     2041 acagatctca atcgttgact ctgattttac gaaaactgta ccaccaaaag taaccgcggc
     2101 aacgggagtc gatgcgctat gtcacgcttt ggaatcttat gtttcagtca aagccaatga
     2161 agtaacgcaa ctattttcac tggaagcgat gaagaaaatt ttgaacacgc tttctcaggc
     2221 atatgaaaat agcgacgaca ctgaagccag agaacaaatg agcttagctt caacggaggc
     2281 ggggattgcc ttttcgaatg cgtcagtcac attgattcat ggaatgagtc gaccggtggg
     2341 ggcacttttt cacattcctc atgggatatc aaatgcgatg ttattgccgg tcttttttga
     2401 attctcaaag gatgctattc agactgagtt agcgacgatc gccagattta tttatccggc
     2461 agccgaagat ttatcgctgg aagaggctgc ggattatctg attaaaaaaa tccaagagct
     2521 ctgtgagcag ctgtcgatcc caacgattcg agattatggt attgatcagc aagcgtttat
     2581 ggcagcctta gacaaaatgg ccgcggatgc gttgaccagc ggaagtccgc aaaataataa
     2641 aaaggtgcct agtcatagtc aaattaagga attatacgta caagcttatg ggtagtaaaa
     2701 ggcggagcaa agagagggct ctacctttta agaataaaag ctacacagga ataattttgt
     2761 aagcgcatac tatgtgtgct taaacaacag aacaggggga taagtaattg agagtaaaag
     2821 taggcgttat cggaacaggt gcaatcggca tcgagcatat cgacaggatc aatcagaaaa
     2881 cacaaggggc ttatgtgaca gcagtctcag atatcaatgt aaaagctgct aaagaggttg
     2941 ccaaacgtgt cgatgctaaa ttctttgaaa ccggagaagc attgatcgct tctgaagatg
     3001 tggatgtcgt tgttgtgact tcttgggacc cgacccatga gcagtatgtg ttagaagcaa
     3061 tcaagcatgg gaaatatgtt ttctgcgaaa agccattagc gatggatgca gcaggctgcc
     3121 gccggatcgt tgatgcggaa gttgcttatg ggaagaaatt ggttcaggtt ggcttcatgc
     3181 gccgctatga ccgcggctac attgaactga aagaagcaat cgaatcgaag caatacggag
     3241 aagcattaat gatgcattgt gcccatagaa atcctagcgc agatgaaaac tacacaacac
     3301 cgatggcgat cagcaacacc gcgattcatg agattgatgt gcttcgctgg ttgctaaatg
     3361 aagattatga atctgttcaa atgatcttgc cgaaaaaaac cagcaactcc catgccgatt
     3421 tgcatgatcc gcagctgctg atctttcaaa caaaatccgg tgtaacgatt gatttggaaa
     3481 tctttgtgaa ttgccgcttt ggctacgata ttaaatgtga tgtggttttc gaaacggcag
     3541 aagtaggaat gacggaccca gcctatacac gaattaaatc ggaagaaaaa aattacacac
     3601 ctgtttcacc agattggcag acccgctttt tggatgccta tgattatgaa ttcaagctgt
     3661 ggatcgattc gatcaaaaat gatgcggttg tcggtcctac cgcttgggat gggtatgtag
     3721 cagcgatcac catgatggct tgtcatgagt ctcgtgaaac aaaaacaaaa gtaatgattc
     3781 aaatggatga acgaccagca ctatacaatg agtaattctc agaaaacgga ggtatttcat
     3841 gaacaacatt agagtaggca tcgtcggttt aggaagatta ggaaaagtac atgcacaaaa
     3901 tttagcaaca ggtgtcagtt gttgtgagct tacggctgcg tgcagtttag ttgaaacaga
     3961 attagcattc gcacagaaga aattaggcgt caagcatact ttttccagct atgaagaaat
     4021 ggtcaaaagt tccgtgatcg atgcagtctt tattgtttca ccatcaggct ttcactgtga
     4081 ccaagtccgc ttggcgatgg aaaatggcaa gcatgtcttt actgaaaaac cattaggcct
     4141 tgaagttgaa gatattaaaa agacccaaaa agtcatcgaa gagcatcctg aacaggtctt
     4201 catgttaggc ttcatgcgcc gctatgatga gtcgtatcag tatgcgaaga aaatggtaga
     4261 agatggcgaa atcggcgaaa tcacactgat tcgttgttat gggatcgatc cgagcgaagg
     4321 cttggaaagc tttgtcaaat ttgccatgaa taacgacagc ggcggcttgt tcttagatat
     4381 ggcgatccat gatattgatt tggttcgctg gtttaccggc caagaagtcg atcaagtgtg
     4441 ggcgattggg aaaaatgcgg cgtatccaga attggatcag gctggtgagc ttgaaactgg
     4501 agccgcaatg atgagcctga gcgataaaac aatagcttta ctagttgccg gcagaaacgc
     4561 agcccatggc tatcatgtcg aaacagagat catgggaacc aaaggaatgc tgcgggtagc
     4621 gcaagcgcct gagaaaaatc ttgtgacgat catgaacgat caagggatca tccgtccatg
     4681 ttcacaaaac ttcccagaac gattcagaga agccttcatt cgtgaagccc aagaatttgt
     4741 ctcatgtatt caagaaaaac gtcaaccagc ggttaatgca gaagatggat tgcaatcaac
     4801 taagatcgcg ttggcttgtc aagaatcatt cgatacgaag agtttagtac aactaaaaaa
     4861 ataagcagga gtgtgagaat atgaccaaac aaattcaatt agccatcgca ccaatcgcgt
     4921 ggaccaatga tgatatgccc gagcttggta gtgaaaatac ctttgaacaa tgtatcagtg
     4981 aaatggccct tgctgggttc accggaacag agattggcaa caaatatcca aaagatccag
     5041 aggtgttgga acaatatttg aatattcgcg gcttaaaggt tgccagtgca tggttcagtg
     5101 cgtttctgac aactaaacct tttgaagaaa ctgccgaagc cttcaaagca catcgggatt
     5161 tcttacatgc gatgggcgct aaagtcatcg tagtagctga gcagggtcat agtatccaag
     5221 ggattatgac agcgccagtc tttgatgata aaccagtttt cactgatgaa gagtggaaaa
     5281 aactggcgga aggattagaa aaattagggg atttggccca cgaaaaggat atggagatcg
     5341 tttaccatca tcacatgggt accggcgttc aaacgacgga agaaatcgat cgtttaatgg
     5401 aaatgactga tccagacaaa gttaaattat tgttcgatac gggacatttg gtcttttctg
     5461 gtgaaaatcc aatcgcggtt tacaaccgtc atcaagatcg tatcaaacac atccatttca
     5521 aagatattcg tcaagaaacg gctgaagaag tagaaaagga aaaagacagc ttcttaaacg
     5581 gcgtgaagaa aggcgtcttc acggttcctg gtgatgggat gattgatttc actccaatct
     5641 ggacagcaat ccatgccagc gactatgaag gctggatcgt agttgaagca gaacaggacc
     5701 cggctaaagc caatccattt gaatatgcag tcaaagccag aagctacatt cgagaggtca
     5761 ccggtcttta atctattgaa aaggagctag acgatgaatc ttttttctat aatcagtttc
     5821 ctagtgattg tcatctgtgt atggttattt gcctattcta gatccagaag tgtcgatact
     5881 tctggatcag aagggttctt catgggaggg cggagcttaa ctgctttgcc aatcgccggc
     5941 acgatcatca tgacgaacct gtccaccgaa caaatagtcg gacaaaatgg tcaaagttat
     6001 catgcaggga tggaagtaat ggcctgggaa gtaactgcta cgattgcgat cgtagctttg
     6061 gctgtgatat tcttgccaaa atattttaaa tacggcatca atacaatctc agatttcatc
     6121 gagattcgtt atgatacggt taccaaacga attatttcga tcttatttat tgtgacctat
     6181 atgacttctt tcttacccgt ggttctttat tctggatcgc tggtgttcaa taagatcttc
     6241 catattgatg agctgctggg cgtccagccg atcgtcgcga tcataattgt agcgatggca
     6301 attggtattg tcggcatcct ctatctgctg atcggcggct tgtcgttaag tgccaatagt
     6361 gactccattt atggagtcgg tctgctggct tgtggtctgc tggtcccaat tttaggctta
     6421 atgaagcttg gtgacggcag ctttgttggc gggatcgaac acgttgtggt aaacacgcca
     6481 tggctgctta actctgtggg atcgatcgac tcggctgttg ttccatggcc gacactattt
     6541 acagggatgc tgtttaacaa tctgtatttc tggtgtacca atcaaatgat cgtccaaaaa
     6601 gcattgtccg gcaagaattt agctgaggca caaaagggcg ctttcctagt cggcgtcttc
     6661 aaaatcttag gtgcgttatt ccttgtcttt ccagggatcg tcgctcgcaa tatttttggc
     6721 gatagtttaa tgtcaaatcc agataacgcg tatccttttt tagtcagtga agtattgcct
     6781 aaaatgatct ttggtatttt cgccgctgtt atctttggcg cgatcttatc atcatttgcg
     6841 ggagctttga acgcgacatc gaccttgttt tcactggatt tttataaacc gcttatcaat
     6901 aagaaagcaa atgataagca aatcgctcgt gctggtaaaa cagtaacggt cgttgtgggg
     6961 attatctcca ttatcgtagc gccattcatt tcttttgcac cggctggatt gtatcagttc
     7021 gttcaagaat tcaatggact atacaacatg ccgctgctcg tgatcattct ctttgccttt
     7081 tattcaaaaa aagcaactgc ttttggggca aaaacgacga ttgccgtgca tatcgtcttg
     7141 tatgcactat caaaaatgct tttccaaaat atccatttcc tttatgtttt gacggcatta
     7201 ttcgttctgg acattatcat tttgatggtg gtttccaaat tgaaacctga tggagaattt
     7261 gtgttgaact cattcgatac aaaggtcgat atcgagcctt ggaaatacac caaggtgact
     7321 gctatagcat tggtagtcat tgttatttta acttatgtgg cattttcacc aattggcttt
     7381 gcaggctaaa aacaggaggg tattatgcat aaggatctat tgattatttg cgagaccgga
     7441 atcagtgcgt cgctgctcgt atcaaaaatg cttgaaacga tcagagccaa aaatctatcg
     7501 tatgagatag attatgcaac gatccgaaac gttgaagaaa aactgaatta taaagactat
     7561 gacgttttac ttttaacgcc gcaggtcgca cgttctgagg aaaaagtaaa agaaatcatc
     7621 aaaaaggaaa aatgtaccgc tcagatcgtt tatatcaaac aagaagattt tcgttatatg
     7681 aatattgaaa acatcattgc aagcatcgaa gaagattaac gagaatcttt gattattgag
     7741 tgtcgaggag gtggtatatg aaaagatggc atgttcgccc cgatcacccc aatatgaagg
     7801 gcggacttat tagaaatacc caatcttgta tttattcaat agggtaagcg gacctcaata
     7861 gccagctcat ccccaaaaag tcgaatggag acacttaaat gagtgtacct attcgacttt
     7921 ttgagactct aagtcaaatc gtgttgttct cattaaatca ctgaaaggaa atgcttcggc
     7981 gtttcctttt ttctttttgt ttttcttcgt gttttgaaaa ttacttacta tttactatac
     8041 gagtagtttc aaataatttt gacatcctaa tcttcaacaa cagaaaaaaa tctaaattat
     8101 aaaatttagg gttgactaaa atataatttt tgtataccat atgatcgtga taatcattat
     8161 catttagaag gagaaagtta tgttagaagt gaaaaagctt aatgtttgtt ataacgattt
     8221 tttagcattg aacgagattt ctttaaaaat acaagaaggt gctttaacag gtattattgg
     8281 tccaaatggt gctggaaaat ctacattgct taaagcaatg ttaaatatta tccctcatca
     8341 gggagaggtc tccattaata atgaagatat caataaaaaa ctggtgaaga ttgcatatgt
     8401 agagcaaaaa gctgatattg attttacttt tccaataaaa gtaaaagaat gtgtatctat
     8461 gggaacatat gccggaatga aagtttttca aagaattaaa aatgcagaat ggcaaagagt
     8521 ttcaaaggct ttggaaaagg tcgatatggg aaaatattct aatcatcaaa taggagaatt
     8581 atctggagga caatttcaac gtgtactttt agcaagatgt cttgctcaaa atgcggattt
     8641 catattttta gatgaaccat ttgtagggat agacttagtt agtgaacgaa taattatgga
     8701 tacgttaaaa gaattgaaac atcagggaaa aacagtgcta attgtgcatc atgatttaag
     8761 caaggtaaag aagtattttg ataatattat tcttttgaat cgaaatctaa ttgctcacgg
     8821 aagtgtagaa tctgtattta atgaagagaa tttaaaaaaa gcctatggag atactatatt
     8881 tattggagag gggggaacgg cttagcctct caatccaata aatatattat ctcaaaagaa
     8941 atgagttaat accaaattaa aataacgatg gttcataggg ttatccaatc aaaaccggaa
     9001 ggttaaaacc ctaactctaa tatacaaggg gaataatatg cttcaaaatt ttattaatgg
     9061 tctgtatgac tttcactttt tacagaatgc tctaattaca tctgtagtta tagggattgt
     9121 ttctggaaca gtaggttgtt ttattatttt aagaggaatg tctcttatgg gtgatgctat
     9181 ttctcatgct gttttgccag gagtagcaat ttcttatatt ttaggtatta atttttttat
     9241 tggtgcgatt gtatttggtc tattagcttc tatcattatt acttttataa aaagcaatag
     9301 tgtaataaaa ggagatacag caattggtat tactttcagt tcttttttag cattaggagt
     9361 tatccttata ggagttgcaa atagctcaac ggatttattt catatcttat ttggaaatat
     9421 tttagctgta caagatattg ataagtggat tacaattggc gtttctgttt tagtgttggt
     9481 tacagttgtt ctatttttta aagaattatt aatcacttct tttgatccat taatggcaaa
     9541 agcaatgggg atgaatgtca gtttttatca ttatctatta atgattctat taactttagt
     9601 agcagtaaca gctatgcaaa gtgtgggaac tatattaatt gttgcaatgt taattacacc
     9661 agctgctaca gcatatttat atgcaaacag tttaaaaact atgatattta tttcggcgac
     9721 agtcggagcg tgctcatcat tgctaggttt gttcattggt tatagtttta acatagcagc
     9781 aggatcaagt attgttttaa cagcggcatt cttatttgta attagttttc taatctcacc
     9841 aaaacaaaaa tttttaagaa agaaggagag aaagttatga tgagaaaatg gaaagcagta
     9901 ctgggaagtc tggggatttt gattgctctt tttatattcg gggcatgttc aacaaatagt
     9961 aaagacaaag atacagtggc ttcgaacgaa aaattaaagg tagtagttac taattcgatt
    10021 ttagcagata ttactgaaaa tatagcaaaa gataaaattg atttacacag tatcgtacct
    10081 attgggaaag atccccacga atatgaacct ttgcctgaag atgttcaaaa aacttcaaaa
    10141 gcagatttga ttttttataa cggtgttaac ttggaaactg gaggaaatgc ttggtttaca
    10201 aaattagtaa aaaatgcgaa caaagaggaa aacaaagact attttgcagc aagtgatggc
    10261 atagatgtta tttacttaga gggtcagagt gagaaaggga aggaagatcc ccatgcttgg
    10321 ttaaatttag aaaacggtat tatttacgct aaaaatattg aaaaacagtt agcggaaaaa
    10381 gatcctgata ataaaaaatt ctataaagaa aatctagata agtatattga aaaattggat
    10441 tctctagaca aagaagctaa atctaaattt gcttcaattc cgaatgataa aaaaatgatt
    10501 gttacaagtg aaggatgctt taaatatttc tcgaaagcgt ataatgtgcc ttctgcttac
    10561 atttgggaaa tcaacactga agaagaagga acaccagatc aaataaaaca cttagttgaa
    10621 aaattacgca caacaaaagt tccctcctta ttcgtagaaa gcagtgtgga cgatagacca
    10681 atgaaaacag tatcaaaaga taccaatatt cctatctatt caacgatttt tactgattca
    10741 attgcagaaa aaggacaaga tggtgatagt tactatgcga tgatgaaatg gaacctggat
    10801 aaaattgctg aaggcctttc gaaataattt ggagggtagg tatggtacaa attaaaacaa
    10861 ctactatact aatttattta ctagcaattc aggaattatc aaaaagaaaa aagaaattaa
    10921 aaaataatga tttagcaaaa gttctaagtg ttagtccagc atctgtaagt gagatgctga
    10981 ctaaacttag atatgaggac tatttagata taggatttca attaactgat aaagggaaaa
    11041 aatttattga cgattacaaa aaaaggtttt aagtaaaagg ctttattttt agggaggata
    11101 agaaaatggc tattggagtg attatgatag gacttatcct aatagctgga tataattttt
    11161 ttaaatcttt ctcggattat tttagaaaag gtgaatgatt tagatgagtc tattaattct
    11221 tgtaggattg ctttttgtat cagttatttt gctctttctc attagtttag ctctaaggaa
    11281 tgagttcagt aatagacgtt aacgattgaa acttcaagtc ctgtgtaaga taatatagtt
    11341 aattcatctt attaggagga agtacccata gaaaccagag attatattac aactcaccaa
    11401 aaattaatag aaagtggact aagccatttt gaaaaagtag gatttcagca aactaagata
    11461 aggcaactgt gcttgaccgc aggcgtaact acgggtgctt tttataaaca ttttacttct
    11521 aaggaagcgt tatttgaaga aattattcag ccgcatatta atgcgcttat taatatgtat
    11581 aatgaagagt ttaccaaata cc
//
LOCUS       DAZKKZ010000078        11588 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.080, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000078 DAZKKZ010000000
VERSION     DAZKKZ010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11588)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11588)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11588
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.080"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..459
                     /locus_tag="ACG8LA_002450"
     CDS             <1..459
                     /locus_tag="ACG8LA_002450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204727.1"
                     /translation="VYFQGGNLMIKKLFLLSILTLAMAGCSDSGLATELITKSTEATT
                     EELKCGNDHSDYRGLNRRCMGILGRSNCKHRCSNRRRCRRSNRKIKRKIKRSNLCCAS
                     YTDVEDAVLLNHVRRCSFMSREVGDEPKLEYAFSFAREDEDNPKTYDILA"
     gene            complement(520..885)
                     /locus_tag="ACG8LA_002451"
     CDS             complement(520..885)
                     /locus_tag="ACG8LA_002451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02328 family protein"
                     /protein_id="HFQ0204728.1"
                     /translation="MRLWHEKLISKLPRQQLLGQHRECCALRGNGWGKKHATVDYVFH
                     YSPYRLFQYHQLVMDEMEKRGYSPAPEWKNPMYRGKSCEAFFDLPTVERNVPIYPEHD
                     EVYLAECLANLEQKGIYLT"
     gene            complement(961..1206)
                     /locus_tag="ACG8LA_002452"
     CDS             complement(961..1206)
                     /locus_tag="ACG8LA_002452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFQ0204729.1"
                     /translation="MSIEEAILLDTLRCRLNFLRTGRSLSQVAVSSALSIPLFKYRKY
                     EEGEEIPSIIELIYIADFYDISVDYLIGRSETASKLK"
     gene            complement(1276..1530)
                     /locus_tag="ACG8LA_002453"
     CDS             complement(1276..1530)
                     /locus_tag="ACG8LA_002453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204730.1"
                     /translation="MITLVRVLFWVPAVALVASIVYLMNWNKERFYLAILTLPAIYFM
                     WKVFNYNYFEPDSVFIEELSGLVLSLLIVILYLIRLNKKH"
     gene            complement(1694..2017)
                     /locus_tag="ACG8LA_002454"
     CDS             complement(1694..2017)
                     /locus_tag="ACG8LA_002454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204731.1"
                     /translation="MLGVIILPFIAILFDLVAAAAYFLQLNYQTSGILFIGMIFQGVI
                     TLLLLVMMLSYKGKRYARIQTKVFVKYVSIRYGIIILSFLVNAIVLFLYVLNYLDINP
                     LIFSR"
     gene            2204..2277
                     /locus_tag="ACG8LA_002455"
     tRNA            2204..2277
                     /locus_tag="ACG8LA_002455"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2238..2240,aa:Ile,seq:cat)
     gene            complement(2662..3159)
                     /locus_tag="ACG8LA_002456"
     CDS             complement(2662..3159)
                     /locus_tag="ACG8LA_002456"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isochorismatase family cysteine hydrolase"
                     /protein_id="HFQ0204732.1"
                     /translation="MLVIIDMQNHILDPNSEFYIPESDQLAERIAQRLAKARQNNEYI
                     LFTRDIPVELKDKEEEREDLQLIPLLSPQENERVIKKYYFTIPPETLAEIQETLFESK
                     EEQKEIEVVGIETNLCVLSNLIGLQSAFPEADFFVDPMLVSSRKHGESALELLKDFNV
                     SIVES"
     gene            complement(3199..4008)
                     /locus_tag="ACG8LA_002457"
     CDS             complement(3199..4008)
                     /locus_tag="ACG8LA_002457"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFQ0204733.1"
                     /translation="MKLAAIDLDGTLLDRNGKIPEENIQALRKFDENGGIVTVATGRN
                     SISAKDIFSELGIGGYLISSNGSLIAEMKDGKMAKVLRRSKIDSDTLRKAFFYAQEAK
                     ISIIASRETQDDQLTFDESNLVKDDPYYEHFNLQNHSFDQILNMLEDPSLSYLKLALT
                     DKSEEKLQKLQRDLQADGIQSVFSDPHFLEITPTGITKAHSLVFLADYLGIESSDIMA
                     FGDQENDIAMLNYSGLSIAMGNAQRQVKEIANQVTLTNEEAGVAYILKNFY"
     gene            4342..5199
                     /locus_tag="ACG8LA_002458"
     CDS             4342..5199
                     /locus_tag="ACG8LA_002458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HFQ0204734.1"
                     /translation="MEKRYGVVPVVTASDENYAPYLSVMIATALENCNKTRRIKFYVI
                     DDGLSEYSKEGLEETVNKYSSNASIQFLTVEKDIYEDFLVSDHITTTAYLRISLPNLL
                     AKEDYKKVLYLDSDVLVLDDIVKLYDEPLNGKTIGAIIDPGQVKALERLGIDSDDLYF
                     NSGVMVIDIDQWNKKEITEKTIHYLSENGDRIIYHDQDALNAVLYEDWEQLHPKWNMQ
                     TSLIFERHPAPNEKYERQYKEGNEKPSIVHFTGHDKPWNTLKDHPYTNLYLKKLAHST
                     LTKVGEINE"
     gene            5192..6094
                     /locus_tag="ACG8LA_002459"
     CDS             5192..6094
                     /locus_tag="ACG8LA_002459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HFQ0204735.1"
                     /translation="MNKKEIAVVASCNTKFVPHLAALFVSVLDNCNPSKFVRFYVIDD
                     DIDFESKQLLRFSVKNARMNSDVEFLKINKEFFTNVVISDRIPETAYYRIAIPELFRG
                     TEVERILYMDCDMIALQDISKLWRLDFGDSIVAAVEDAGFHQRLEKMKISAKSMRYFN
                     SGLMLINVKKWLDENITQKVLDFIEHNPEKLRFHDQDALNAILHDRWLPLHPRWNAQG
                     YIMAKAKKHPTAAGEREYEETRNNPYIIHFSGHVKPWSKDFEGPTKKYYEKYAGMTAF
                     RCVAKFPKYPKYAKVQPKTDVVVK"
     gene            6127..6477
                     /locus_tag="ACG8LA_002460"
     CDS             6127..6477
                     /locus_tag="ACG8LA_002460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HFQ0204736.1"
                     /translation="MEITMSKNAVETLIEKVGENTKIALALINDSDPFLRDKGAFAKG
                     SFFQIIPFVSEFGEYATKIEHPLLDIYTSKLEQNYFGKRLNMDFNKQLDSFSLENEIA
                     VLDYNIKLKNCFFS"
     gene            6526..7449
                     /locus_tag="ACG8LA_002461"
     CDS             6526..7449
                     /locus_tag="ACG8LA_002461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HFQ0204737.1"
                     /translation="MDEEKNVIETDEKKYNWLVLDSAKPEEIEQAIEEFELPDDIFVG
                     TEYPEEVSRMERLYETKLEHPFSLVVINLDQSDNRIEKKLTPISFVLSDNLLITCIDR
                     KTEFVDRLLTKHGNHLNSFEKIITYTLLDIYTHYVKELREMKKRIDALDKAARKTTEN
                     EELYKQADLERDIVYIDHTLRDQRETMDQLWNSETFIKRLDDEQLLYDVHLRQRQTEK
                     MIEIYRDLLESIGDLFNGMMDNNLNHIMKYLDSAALIISVPALFAGIWGMNTGGLPGK
                     SSALGFILVVFGSLIAAVVLGYHLYRKDYTN"
     gene            7527..8420
                     /locus_tag="ACG8LA_002462"
     CDS             7527..8420
                     /locus_tag="ACG8LA_002462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HFQ0204738.1"
                     /translation="MTEPKLIDPRNLYHTEKFPKQDQDTPALQQNMIPVPDCGEESYE
                     GNNQLENRRVLITGGDSGIGRAAAIAFAREGADIALQFFPGEEKDAEEVAKYVKDAGR
                     KIVLLPFDLRDEQAPKEIIDKAVSELGGLDTMVLNAGQQISCQSIAELPLEQVKDTFM
                     INIIAMFALVKEAVPHIPAGGAIVTTTSVQAFNPSEHLLDYAATKASIANFTIGLAKQ
                     LAPKGIRVNGVAPGPIWTPLQLDEGQPSDSIPEFGQQSLLERAGQPGELAPVYVFLAS
                     NKASYVTAQIYGVTGGEAINL"
     gene            8458..9021
                     /gene="amaP"
                     /locus_tag="ACG8LA_002463"
     CDS             8458..9021
                     /gene="amaP"
                     /locus_tag="ACG8LA_002463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HFQ0204739.1"
                     /translation="MNKGVKTIGVIGTLLLLSVLLFAILLSATYPLPFQLEKFRFFSI
                     TNSYVQQYVFWLAVAFAILTIITLLVFLFYPKTIGNFLLKHGDGELTLDKKAIEGMVR
                     SHLHEDEFIHSPKVNVKATKNKIAVNVKGELKRTSALIGKTGTLMKEIENEVQHILGT
                     KEPVKVSVKYTGFEEPAKRSNDRKRVE"
     gene            9035..9223
                     /locus_tag="ACG8LA_002464"
     CDS             9035..9223
                     /locus_tag="ACG8LA_002464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HFQ0204740.1"
                     /translation="MKELFSTYKLPIIFGVLGLILAVLWITVGFFKTLLILIMAAIGV
                     AIGFYLKQTKILDHYFKS"
     gene            9236..10138
                     /locus_tag="ACG8LA_002465"
     CDS             9236..10138
                     /locus_tag="ACG8LA_002465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HFQ0204741.1"
                     /translation="MNNNNKNNNNKMNNQKPVSAHPDPTTPNQSNGVNDEKNKTAPVS
                     AHPDPVVPNVQQGVEEKKHDAEKHAPHHPGTPESKVPEQHDAIDPSKPVEEQKHPSDH
                     AKAQEKLSSDHTNGQGKLGSDHTNNQGKHDSEQEDSMRGELNYEDKVVQKIIGIAIEQ
                     VDGLLSANGGFFSNVAGKLVNTDNVTAGIETEVGKKQVAVDMDVIVEYGKDIEKIFEE
                     MQEVIGKEVKNMTHLEVIEVNANVVDIKTKEEFEKDQETVQDKVTDAAKKTGEFASNQ
                     TDKVKSAAGSGAQKVKENTEPRVQ"
     gene            10170..10412
                     /locus_tag="ACG8LA_002466"
     CDS             10170..10412
                     /locus_tag="ACG8LA_002466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HFQ0204742.1"
                     /translation="MGFIWSLIVGGIIGAIAGAITNKGSSMGIIANVVAGLVGSALGQ
                     ALLGSWGPSIAGMAIVPSLIGAIILVLIVSFFARKL"
     gene            complement(10668..11039)
                     /locus_tag="ACG8LA_002467"
     CDS             complement(10668..11039)
                     /locus_tag="ACG8LA_002467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204743.1"
                     /translation="MPFIVYFFLSLLVIYIPLPTFFLLVNRLAEQHDTIAALTKLCLL
                     LFVCLDYFTSYYWLKQTRVKKRYYFFLVFFNLFEFLIHCFLLHQYHTIHLWIIWVFKV
                     VVLFCMFTFPISRKFREALFY"
BASE COUNT         4122 a         1979 c         2196 g         3291 t
ORIGIN      
        1 gtctattttc agggggggaa ccttatgata aaaaaactat ttttactatc aatattaacg
       61 ctagcaatgg caggttgttc tgactctggc ttagcaactg aactgatcac aaaatcaact
      121 gaagccacga cagaggagtt aaaatgtgga aacgatcaca gtgactacag aggcttaaat
      181 cgacgatgca tgggaatatt aggcagaagc aattgtaagc atcgatgtag taatcgaaga
      241 aggtgtagaa gaagcaacag aaaaatcaaa agaaagatca aaagaagcaa tctgtgctgt
      301 gcatcgtata cagacgtcga agatgcggta cttttaaacc acgtcaggag atgttcattt
      361 atgtctaggg aagttggcga tgaaccaaaa ctagagtacg cttttagttt tgcacgtgag
      421 gatgaagata accctaaaac ttacgacatt ttagcttgat ctaagatggt taaagctttt
      481 taatgaagta agaggagata gaaggctttt ctagttatat taggtaagat aaattccttt
      541 ttgctccaaa tttgctaaac attctgctag ataaacttca tcgtgttccg gataaatcgg
      601 cacgttgcgc tctacagtag gtaaatcaaa aaatgcttcg catgatttgc cacgatacat
      661 aggatttttc cactctggtg ctgggctgta accacgtttt tccatttcat ccatgacaag
      721 ctgatgatat tggaataatc tataaggaga atagtgaaaa acataatcca cagtagcatg
      781 tttctttccc cagccatttc ctcttaatgc acagcattcc cgatgttgtc ctaaaagctg
      841 ttgacgagga agctttgaaa tcaatttttc atgccataat cgcatagaaa tgtctccttt
      901 atatatagat tgttaacctt agacgttaaa tgaaaaaacc agcaccaagg ctggaaaaaa
      961 tcacttcagt ttgcttgctg tttctgagcg accaattagg taatcaacgg aaatatcgta
     1021 aaagtcagcg atatagatta attcaatgat gcttggaatt tcttctcctt cttcgtactt
     1081 acgatatttg aataaaggaa tacttaacgc gctagaaaca gctacttgag ataaagatcg
     1141 gccagttctt aagaaattca gacgacaacg taaagtatcc agtaaaatag cttcttcgat
     1201 actcatttaa tcacctttca ttatagtaga atagttataa tgactataga aagctacaca
     1261 tgcaatcaat agtactcaat gttttttatt taaacgtatc aaataaagaa tgacgatcaa
     1321 taaagacaaa accagtcctg ataattcttc tataaaaaca ctatcgggtt caaagtagtt
     1381 gtaattaaaa actttccaca taaagtagat agccggaaga gtcaaaatag ctaaataaaa
     1441 ccgttctttg ttccaattca taagataaac aatacttgcg accagtgcga ccgcaggcac
     1501 ccaaaacaaa actctcacca acgtaatcat gtaacggact cctcaacgat tcatataata
     1561 aaagataaca tgttattgca tacatcacaa atgaaatgct aggaaaataa aagaagaata
     1621 gatcaatgaa aaatgaaaaa gcagaacagt tttctgctga taagcaggaa ctgttccgct
     1681 gaatgtgtct tatctatcga gaaaaaatca atggattgat atctaagtaa ttcaatacat
     1741 ataaaaagag gacgatcgca ttcactaaaa aggaaagaat gatgatccca tagcgaatgg
     1801 aaacatattt aacaaatact tttgtttgaa tacgggcata tctttttcct ttatagctga
     1861 gcatcatgac aagaagcaaa agggtaatca caccttgaaa aatcattcca ataaacagaa
     1921 ttcctgaggt ttgataattt aattggagaa aataagctgc tgccgcaact aaatcgaata
     1981 aaatcgcaat aaatggcaaa ataatcactc ctaacattga gaataaataa aagaataaca
     2041 ttttttctaa aataagcaaa taaaaattaa agtaacaaaa tagttatgac acaagtaaaa
     2101 gaaataagaa taacaatatt attttactta tattttgaaa cttgtgagag tttgtcattc
     2161 gtgctatagt tgaaaagtaa caaaaataaa ttttatttat gatgtacctt tagctcagtt
     2221 ggttagagca gacggctcat aaccgtccgg tcgtaggttc gagtcctaca aggtacataa
     2281 gaggttgtga aaaagctgcc ctgcatcaag taataagaac agccaagtaa aaacagcttc
     2341 ttatgttttt acttggctgt tcttattact gcagatgcaa gcttttgaat accgtttaag
     2401 gaagaggttg tgaaatcagc gttttgacct gagtattagc ttaacaaacg gaaaaatagt
     2461 tcctcatatt ttgccgtttg ttaagctaat accgagggtc agctgattga acaccattta
     2521 agaaagaggt cgtgagcctg ccgtttcact ctgtgtcata aaaaagccaa tctactttga
     2581 tagaaaaagc acgtaggact aaaacagttc tgcgtgcttt ttttattgtg tgttaaatat
     2641 cgtaaatgaa gatagatatt tttatgattc gacgatagag acgttgaaat ctttcaacag
     2701 ctctaaagcg gattctccgt gttttctact ggagactaac attggatcaa caaaaaagtc
     2761 tgcttcagga aaagcactct gcaggcctat cagattagag agtacacaca agtttgtttc
     2821 aatcccgact acttcgatct ctttttgttc ttctttgctt tcaaataaag tttcctggat
     2881 ttcagctaaa gtttcaggtg gaatcgtaaa gtaatacttt ttaatcactc gttcattttc
     2941 ttgtggagaa agaagaggga tcaattgcaa atcttctcgt tcttcttctt tgtccttcag
     3001 ttcaactggt atatcccgtg tgaagagaat atattcatta ttttggcgtg ctttagctaa
     3061 tctttgagca atacgttctg ccaattgatc tgactctgga atataaaatt cgctgtttgg
     3121 atcaagaata tgattttgca tatcaataat aactaacatt ttctttcctc ctacattcat
     3181 atcgtcattt tattcttttt aatagaagtt ttttaaaata taagcaacac cagcttcttc
     3241 attcgtcagt gttacttggt ttgcaatttc ttttacttgt cgctgtgcat tccccatcgc
     3301 aatactcaac ccgctgtaat tcaacatagc aatgtcgttt tcttgatcgc caaaagccat
     3361 gatgtcactc gattcgattc caaggtaatc cgccagaaaa acaagtgaat gagctttagt
     3421 gatacctgta ggcgtgattt ctaagaaatg cggatcagag aatactgatt ggataccatc
     3481 tgcttgcaga tctctttgta gcttctgtag tttttcttca ctcttatctg ttaatgctaa
     3541 tttaagatag ctaagagaag gatcttccaa catatttaaa atttgatcaa aagaatggtt
     3601 ctgtaaattg aaatgttcat aataagggtc atctttgact agatttgatt catcgaatgt
     3661 cagctgatca tcttgggttt ctcggctagc aatgatggat attttcgctt cttgagcata
     3721 gaagaaggct tttctcagtg tatcgctatc tatttttgaa cgtctgagaa ctttcgccat
     3781 ttttccatcc ttcatttcag caatcagtga accattggaa gaaatcaaat agccaccgat
     3841 tcctaattcg gaaaaaatat ctttagcaga aatgctgttc cttccggtag cgacggttac
     3901 gattccgcca ttttcatcaa atttccgaag tgcttggata ttttcttctg gtatctttcc
     3961 atttcgatca agcaaggtac cgtctaaatc aatcgctgct agtttcattt tatcttccta
     4021 ctttcttttt acatatctat tttcctgtta ccttaagatt aaatgagaat ttaaaaaaat
     4081 gaaactaact tgctttgtca ttatgaattt tttcaaaaaa cattcttaag aaaaaggtgg
     4141 ctatatatag tagtttttgg tcaatacctt tgaataaaaa gccatgaaaa acgaatagtt
     4201 agcgcttacc gatgcgtttt gtgataaaaa aattttaaaa tattcaatga aaacaaagca
     4261 tatattttgc tttaaaacca aatgaggaat attctagatg tagaacaggt tagaaaaaga
     4321 ttagaaaaag gagtgatttt gatggagaag agatacggcg tagttcctgt ggtaactgct
     4381 tcagacgaaa attatgctcc ttacttgagc gtgatgatcg caactgcatt agaaaattgc
     4441 aataaaacaa gacgcataaa attttatgtg attgacgatg gtctatcaga atatagtaaa
     4501 gaaggattgg aagaaacggt aaataaatat tcaagtaatg caagtatcca attcctgaca
     4561 gtggaaaaag atatctacga agacttccta gtcagtgacc atatcacaac taccgcttac
     4621 ttaagaattt ctttaccaaa cttattagct aaagaggatt ataagaaagt cctttactta
     4681 gattcagatg tgttagtact agacgatatc gtaaaactat atgatgagcc gttaaatgga
     4741 aaaacaatcg gcgctattat cgatccaggc caagtgaaag ctttggaaag attaggaatc
     4801 gattccgatg acttgtactt caattcagga gtgatggtga ttgacattga tcaatggaat
     4861 aaaaaagaaa ttacagaaaa aactatccat tacctcagtg aaaatggcga tcgaatcatc
     4921 tatcacgacc aagatgcttt gaatgctgta ctttatgaag attgggaaca acttcatcca
     4981 aaatggaaca tgcagacttc gctgattttt gaacgtcatc cagcaccaaa tgaaaaatat
     5041 gaacgtcagt ataaagaagg aaatgaaaaa ccttcgatcg ttcactttac aggacatgat
     5101 aaaccttgga atacgttgaa agatcatccg tataccaatt tatacttaaa aaaattagca
     5161 cacagtactc taacgaaagt aggcgagatc aatgaataaa aaagaaatag cagtagtcgc
     5221 aagttgtaac acaaaattcg taccacattt agctgcatta tttgtctcag tattagataa
     5281 ttgcaacccg tctaaatttg ttcggttcta tgtgattgac gatgatatcg attttgaaag
     5341 taaacagctt ttacgcttct cagtgaaaaa cgcacgaatg aactcagatg tggaattctt
     5401 gaaaatcaat aaagaattct ttacaaatgt ggtaatcagc gatcgtattc cagaaacagc
     5461 ttattatcgt attgcgattc cggaattgtt ccgcggcaca gaagttgaac gtatcttata
     5521 tatggattgc gacatgatcg ctttacaaga tatctctaaa ttatggcgtc ttgacttcgg
     5581 tgattcaatc gtagcagctg ttgaagacgc tgggttccat caacgactgg aaaaaatgaa
     5641 aatttcagct aaatcaatgc gttatttcaa ctcaggtttg atgctgatca atgtgaaaaa
     5701 atggttagat gaaaatatta cgcaaaaagt attagatttc atcgaacata atccagaaaa
     5761 attacgattc catgaccaag atgcattaaa tgctatctta catgaccgtt ggttaccact
     5821 tcatccgcgt tggaatgcac aaggctatat catggcaaaa gcaaaaaaac atccaacagc
     5881 agcaggtgaa cgtgaatacg aagaaactcg caacaatcct tacattatcc atttttcagg
     5941 acatgtgaaa ccgtggagca aggattttga agggccaacg aagaaatatt acgaaaaata
     6001 tgcagggatg acggctttcc gttgtgtagc taaattccct aaatatccaa aatatgcaaa
     6061 agttcaacca aaaacagatg tagttgttaa ataatagaag acaacaactg aagaggggga
     6121 gtaggaatgg aaattacaat gtctaaaaat gcagtagaga cgttaattga aaaggttggg
     6181 gaaaatacaa aaatcgcact cgcgcttatc aatgattccg atccatttct aagggacaaa
     6241 ggtgcttttg caaaaggcag cttttttcaa atcattcctt ttgtttcgga atttggagaa
     6301 tatgcgacta aaatcgagca tccattattg gacatctata catctaaatt agagcaaaat
     6361 tatttcggta aacgattgaa catggacttc aacaaacagc ttgacagctt ttcattagaa
     6421 aatgaaatcg cagtactcga ttataatatc aaattaaaga actgcttctt cagctaatag
     6481 tttcgagaaa gtccaaaaag gaggtataca ttgagatact actttgtgga tgaagaaaag
     6541 aatgtaatag aaacagatga aaaaaaatat aattggctcg tacttgatag tgcaaagccc
     6601 gaagagattg agcaagcaat cgaagaattc gagcttcctg atgatatttt cgtaggaacc
     6661 gaatatccgg aagaagtttc tcggatggag cgcctttatg agacgaaact agagcatcca
     6721 ttttctttgg tagtgattaa tctagatcag tcagataatc gtatcgaaaa aaaattaacg
     6781 ccaatatctt ttgtactttc cgataatctc ttgattactt gtatcgatag aaaaaccgaa
     6841 tttgtggatc ggctgctgac aaagcatgga aatcatttaa actcgtttga aaagatcatc
     6901 acgtatacat tattagatat ttacacccat tacgtgaaag aactaagaga gatgaaaaag
     6961 cgaattgacg ctttggataa agcagctcgt aaaacaacgg aaaatgaaga actgtataaa
     7021 caggcagatc ttgaaagaga catcgtatat atcgatcata ccttaagaga tcaacgggaa
     7081 acaatggatc aattatggaa ttctgaaact ttcatcaaac gtttagacga tgaacagcta
     7141 ctctatgatg tccatttgag acagcgacaa acagaaaaaa tgatcgagat ctatcgagat
     7201 ttattagaga gtattggtga tctattcaac gggatgatgg acaataatct aaatcatatc
     7261 atgaaatatc tagattcagc tgcattaatc atttccgttc cggcgttgtt cgcagggatt
     7321 tggggaatga atacaggagg attaccgggt aaaagttctg ctctaggctt tatactcgta
     7381 gtctttggct ctttgatagc agcagtagtt ttaggttacc atttataccg gaaagattat
     7441 acaaattaaa gaatctattt aaaacaggta tcaaacaaag aaatttgttt tggcaataca
     7501 atttaaaaac taggaggaat acagcaatga cagaaccaaa attaatcgac ccgcgaaact
     7561 tgtaccatac ggagaaattt cctaaacaag atcaggatac accagcttta cagcagaata
     7621 tgattcctgt tcctgattgt ggagaagaat cctatgaagg caataatcaa ctagaaaacc
     7681 gccgtgtact aatcactggt ggagattcag ggatcggtcg tgcagcagcg attgcatttg
     7741 ctagagaagg ggcagatatc gctcttcaat tcttcccagg agaagaaaaa gatgcagagg
     7801 aagtagcaaa atacgtgaaa gatgcaggac gtaagattgt cttactacct tttgatcttc
     7861 gtgacgaaca agcacctaaa gaaatcatag ataaagccgt gagtgaactt ggcgggctag
     7921 atacgatggt actaaacgca ggacagcaaa tttcttgtca gtctattgct gagttaccac
     7981 ttgagcaagt caaagacaca tttatgataa acatcatcgc tatgtttgct ttagtgaaag
     8041 aagctgttcc gcatatccca gcaggaggag caatcgtaac aacaacttct gttcaagcat
     8101 tcaatccaag cgaacattta ttagattacg cagcaacaaa agcttcaatc gctaacttta
     8161 cgatcggttt agcaaaacag cttgcaccta aaggaatccg tgtaaatggt gtagcacctg
     8221 gtccaatctg gacaccatta caactagacg aaggacaacc ttctgattcg atccctgaat
     8281 ttggtcagca aagtttacta gaacgtgcag gtcagccagg agaattagca ccagtttatg
     8341 ttttcttagc atcgaataaa gcaagttatg ttacagccca aatttacgga gtaactggtg
     8401 gagaagcgat caacttataa gaagttgatc gtttcacccc tatgaggagg tgcgaaaatg
     8461 aataaaggtg taaaaacgat cggagtgatc ggaacattac ttttgctatc tgtgcttttg
     8521 tttgcgatac tattaagtgc aacctatcca ttgccttttc agctagagaa gtttcgattc
     8581 ttttccatca ctaattcata cgtgcaacaa tatgtatttt ggcttgccgt tgcatttgct
     8641 attttgacaa ttatcacgtt acttgttttc ctgttttatc caaaaacaat cggaaacttt
     8701 ctactgaaac atggtgatgg ggagttgacg ttggataaaa aagcaattga aggaatggtt
     8761 cgttctcact tgcatgaaga tgaattcatc cattcaccaa aagtaaatgt caaagcaacg
     8821 aaaaacaaga tcgccgtcaa tgtaaaaggg gagttgaaac gaacttcagc actcattggt
     8881 aaaacaggaa cattgatgaa agaaatcgaa aatgaagtac aacacatatt gggaacaaaa
     8941 gagccagtga aagtatcggt gaaatacaca ggctttgaag aaccagctaa acgaagcaat
     9001 gaccgcaaac gagtagaata gggggggacc aaaaatgaaa gaactatttt cgacatacaa
     9061 gctccctatc atctttgggg tacttggatt gatattagcc gttttatgga tcaccgtggg
     9121 ctttttcaag accttattga tcttgatcat ggcagcgatc ggcgtcgcta tcggttttta
     9181 tctgaaacaa acgaaaatct tagatcacta ttttaaatct taggaggaaa catccatgaa
     9241 taacaataac aaaaataata acaataaaat gaacaaccaa aaaccagtgt ctgcacatcc
     9301 agacccaacg acaccaaacc aatcaaatgg tgtgaacgat gaaaagaaca aaacagcacc
     9361 agtatctgca catccagatc cagtagtccc taacgttcaa caaggagtag aagagaagaa
     9421 acatgatgca gaaaagcatg cacctcatca tccaggaact ccagaatcta aagttccaga
     9481 acaacatgat gcaatcgatc cttctaaacc tgtggaagag caaaaacatc cttctgacca
     9541 tgcgaaagca caagaaaaac ttagttctga ccacacaaac ggacaaggaa aacttggttc
     9601 tgatcataca aataaccaag gaaagcatga ttctgaacag gaagattcaa tgcgcggtga
     9661 gctgaattat gaagataaag ttgtgcaaaa aatcatcgga atcgcaattg aacaagtaga
     9721 cggtttatta tctgcaaacg gtggtttctt ctctaatgtg gcaggaaaac ttgtgaatac
     9781 agataatgta acggctggga tcgaaacaga agtcggtaaa aaacaagtag cagttgatat
     9841 ggatgtcatt gtggaatatg gcaaagatat cgaaaaaatc tttgaagaaa tgcaagaagt
     9901 aatcggcaaa gaagtaaaaa atatgacaca tttagaagtg atcgaagtca acgctaacgt
     9961 agtggacatc aaaacaaaag aagaatttga aaaagatcaa gaaacggtgc aagacaaagt
    10021 aactgacgca gcgaaaaaaa ccggtgaatt tgcttcgaat caaacagata aagtaaaatc
    10081 agcagctgga agcggcgcac aaaaagtaaa agaaaataca gaaccacggg ttcagtaata
    10141 aggaagtaaa acattaggag gaacgaaaca tgggatttat ttggtcactt atcgtcggag
    10201 gaattatcgg agcaattgca ggagcaatca cgaataaagg ttcttcgatg gggattattg
    10261 caaatgtcgt agcaggttta gttggatcag cacttggtca agcattatta ggttcttggg
    10321 gaccaagtat tgcaggaatg gcaatcgtgc catcattgat tggtgccatc attttagtac
    10381 taatcgtatc attctttgct cgaaaactgt aaaaagactt ttaaaaagag gtcgtgaaaa
    10441 agctgttctt catcaagtaa taagaacagc caaacaaaaa tagcttctca tatttttcat
    10501 ttggttgggc atattatcga agatgcaagc ttttgaacac tgtttatacg gaataagagg
    10561 ctgtgacaag acttttgtca cagcctctta tttatgcggg caaattccca attagatttt
    10621 taaaagtttt tccttaaatg tgtctttatt gatacagaga agcttcttta ataaaacaat
    10681 gcctccctaa attttcttga gataggaaag gtgaacatac aaaataatac gaccactttg
    10741 aaaacccaga tgatccacaa atggatcgta tgatactgat gaagtaaaaa gcaatggatc
    10801 agaaactcaa agagattgaa aaagacaagg aagaaataat atctcttttt tactcttgtc
    10861 tgttttagcc aataatagct cgtaaagtaa tctagacaaa caaatagaag taaacaaagt
    10921 ttcgtaagag cagcaatcgt atcatgttgc tctgctagac gattgacgag caggaaaaat
    10981 gttggtaatg gaatatagat cacgagtaat gaaagaaaaa agtaaacaat aaatggcata
    11041 ctattcctcc taattgtgtg agttcgccct cattttaaaa taacgatatt tgtttgtgaa
    11101 gctttttcgt gtcgtaacaa atgttatcta atgtattttt aaataaataa tcattattat
    11161 caaaataatg ttaaaaataa aaaagaattg tccatcactg ttattcaaat cattttatca
    11221 aaactacata gtaaatgtta aaaagcaaca tgacataata tatagaaggc tttacagtat
    11281 atatgggagc ttactaaaaa agaatggagt aagagttaac acaatgggcc attagctgaa
    11341 gttttaagca cttcaaggta tgaaacagaa tggcctgtaa tactacatga ttatttagac
    11401 tgctcaaact gctatcagtc tggtggaatg aataaagtat tatactaaaa gcagatccaa
    11461 ctacaacgta acaggaaacc agttgtatca ggaaaagtga tagtacatgg agaagaaaag
    11521 gccccctttg tatgagtcag tacatatctt atttatagat aaaacggtat tcaatcgaaa
    11581 taaaaaat
//
LOCUS       DAZKKZ010000079        11255 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.081, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000079 DAZKKZ010000000
VERSION     DAZKKZ010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11255)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11255)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11255
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.081"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(17..1246)
                     /gene="hflX"
                     /locus_tag="ACG8LA_002468"
     CDS             complement(17..1246)
                     /gene="hflX"
                     /locus_tag="ACG8LA_002468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HFQ0204744.1"
                     /translation="MEEKVIIVGVETEANQRYFSESMEELVQLTNTASGEVVFTITQK
                     RPQVDRQTIIGKGKLQELVQQADAHEADLIIFNHELTPRQSQLITDAVGLPVIDRVQL
                     ILDIFAMRARSKEGKLQVELAQLEYLLPRLVGQGKTLSRLGGGIGTRGPGETKLETDR
                     RHIRNKIFAVKKELKEVEAHRERNRQKRKNSEIFQIGLIGYTNAGKSTILNLLTQADT
                     YSKDQLFATLDPLTKRWRFAEGFEITVTDTVGFIQDLPTQLIDAFHSTLEESQNMDLL
                     LHVVDASSPDRILQEQTVLKLMDELNMKEMPILTVYNKADQIDPAMFTPTLFPNVLIS
                     TQTKEGKMALIEAIKRQLMELMTPYTLSVPSNEGQKLSELRRQTMVLDEAYMEETNEY
                     EVKGFAKTNSKWLRKNQ"
     gene            complement(1248..2165)
                     /gene="miaA"
                     /locus_tag="ACG8LA_002469"
     CDS             complement(1248..2165)
                     /gene="miaA"
                     /locus_tag="ACG8LA_002469"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0052381 - tRNA dimethylallyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HFQ0204745.1"
                     /translation="MEKVLVIVGPTAVGKTALSVELAQLFGGEIISGDSLQIYKNLDI
                     GTAKIKEEEMNNVPHHLIDVIEPTQRYSAADFQHSGRQLITEIANRGHLPIIAGGTGL
                     YIQSLLYDYQLGATEEANPEIRKKYETLAETIGSQALWNQLKEKDPAAAEKIHWNNQR
                     KVIRALEVLETTGHSITAPKEEPKQLYDYLMIGLDTKRSILYERINQRVDLMLAEGLV
                     AEARKVYELGEVQASQGIGYKEFFPYFEGKETLEEATEQVKLHSRRYAKRQLTWFRNR
                     LDAQWFDLISEPNQKSQIEQTIKKWLEAE"
     gene            complement(2169..2906)
                     /locus_tag="ACG8LA_002470"
     CDS             complement(2169..2906)
                     /locus_tag="ACG8LA_002470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HFQ0204746.1"
                     /translation="MLQIYAHRGSSGTHPENTLPAFAEAVRVGADGIELDVHLSKDGY
                     LIVMHDEEVDRTTNGKGLIREKTLEELKKLNAGGKFSKEFPAAKVPELREVLGLLLQK
                     NYRGMLMIEIKTDQYEYPGIEEKLAETLKSRDWPFQHAYCSFHLDSLEKIALLEPEIQ
                     LDLLMSTSDKKIQLAAETPYIEGVHPKNTWLFEHPVQAADFPKAIRAWTINDEEEMAK
                     CQELKIDGIITDFPEKALRWKQSTKSR"
     gene            complement(2997..3524)
                     /locus_tag="ACG8LA_002471"
     CDS             complement(2997..3524)
                     /locus_tag="ACG8LA_002471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204747.1"
                     /translation="MIVGITGLIGVLTGAVVVYIGMILQMRHLENKEQRRRELELKVK
                     EIETLNQLNKKINEILQKRTTLMEEYVSFDAFDDCYITIDDFAYLQSFSAQNSFYLPN
                     YILDELFKNISHRKVILSPDETMKIGGYAYKGGRVILENFTDSLTEMINEKKAQLKTM
                     TRQPIGFFSKDDVWS"
     gene            3704..4297
                     /gene="clpP"
                     /locus_tag="ACG8LA_002472"
     CDS             3704..4297
                     /gene="clpP"
                     /locus_tag="ACG8LA_002472"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009368 - endopeptidase Clp complex
                     [Evidence IEA];
                     GO_function: GO:0004176 - ATP-dependent peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HFQ0204748.1"
                     /translation="MNLIPTVIEQSSRGERAYDIYSRLLKDRIIMLSGQVTDDLANSI
                     IAQLLFLDAQDSEKDIYLYINSPGGSVTAGMAIYDTMNFVKADVQTIVMGMAASMGSF
                     LLTAGTKGKRFALPNAEIMIHQPLGGAQGQATEIEIAARHILQTRERLNKILAERTGQ
                     PLEVIEKDTDRDNYMTAEQAKAYGLIDEVMENSSSLN"
     gene            complement(4401..4886)
                     /locus_tag="ACG8LA_002473"
     CDS             complement(4401..4886)
                     /locus_tag="ACG8LA_002473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HFQ0204749.1"
                     /translation="MERFIASNATVIGDVTLSEDVTIWYQAVLRGDSNWIKIGQRTNI
                     QDGTIIHVDHDAPVDIAENVTVGHQCMLHGCTIEKGALIGMGTTILNHAVIGENSLIG
                     AGSLVTEGKVIPPNVLAFGRPAKVIRPLTKEEIQKNKENIQHYVEIGRMHAQGKFKEQ
                     R"
     gene            complement(5039..5236)
                     /locus_tag="ACG8LA_002474"
     CDS             complement(5039..5236)
                     /locus_tag="ACG8LA_002474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204750.1"
                     /translation="MEQFLNEKITEAKREVDRLTHVCQTKPFDSADFFENEFQIERLA
                     AQIEVYELILKKVIEENIDVQ"
     gene            complement(5331..7091)
                     /gene="efrB"
                     /locus_tag="ACG8LA_002475"
     CDS             complement(5331..7091)
                     /gene="efrB"
                     /locus_tag="ACG8LA_002475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_029485765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrB"
                     /protein_id="HFQ0204751.1"
                     /translation="MKKTFSSLKRLARYIRPYRETFLLVILFTVLTVAFNVALPYVTG
                     LPTTEISRNIANGESINFSYIFKCLIWITVVGIGYCISQLLSGVLMTNVVQSAMHDLR
                     RDIEEKINRLPVSYFDKNQQGNILSRVTNDVDAVSGALQQAFIGIVNAILGITLAAAM
                     MFYIQPMMALISMIMIPTSIWISKRVINASQKYFQSMQNSLGELNGYVQENMTGFSVL
                     KVYGREKETLEGFKKVNHSLKYFGFRAAFISGLMMPLVQLTAYATYIGMAVLGSFYVI
                     TGAIVVGQLQAFIQYIWQISQPMGNVTQLSSVLQSASAATKRVFEILDEPEEKENKVD
                     ASLPETILGDVTFDHVDFAYDPKKPLIQDLNFEVKAGQTVAVVGPTGAGKTTLINLLM
                     RFYDVDKGAIRIDGIDTKSMSRSDVRSLFGMVLQDAWLYQGTIADNIRFGKLDATDYE
                     VVDAAKTANVDHFIRTMPDGYDMAINSEGDNVSLGQKQLLTIARAVVSDPKILILDEA
                     TSSVDTRLEALIQKAMDRVMEGRTSFVIAHRLSTIRDADLILVMDQGQIIEKGTHESL
                     LAQGGFYEKLYNSQFAEEAE"
     gene            complement(7088..8818)
                     /gene="efrA"
                     /locus_tag="ACG8LA_002476"
     CDS             complement(7088..8818)
                     /gene="efrA"
                     /locus_tag="ACG8LA_002476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrA"
                     /protein_id="HFQ0204752.1"
                     /translation="MKLMWHYTMRYKKFLFFNFICVFGFILIELGLPTILARMIDVGI
                     RNDDFDYVKQQGIFMIVITVIGIILNILLGYFGSRITTNIVADIRDDLFEKIQSYSHQ
                     EYENLGVSSLITRTTNDAYQIMLFLQNILRIGFMAPMMFIVSLYMVMRTSVTLSLYVV
                     GALPLLLLAVVAIAKVSEPLSKKQQKNLDKINSILRENLSGLRVIRAFVNEKFEEKRF
                     AVVNENYASSSKSLFRLMAVAQPGFYFLFNIVMVLIIWSGAVQIDAGELRVGDLIAFI
                     EYIFHALFSFMLFASVFMMYPRAAVSAGRIQEALDAKPSIVEDPNGISDTKTKGYIEF
                     QNVTFAYPGHSQEPVIRNVSFTASPGETVAFIGSTGSGKSTLIQLIPRFYDVSEGKIL
                     IDGVDVRDYRLSKLRDKIGFIPQKALLFTGTIADNLRYGKEDATQEEMERAAEIAQAS
                     EFISRKPDGFNEHLSEGGSNFSGGQKQRLAIARAIIRRPEIYIFDDSFSALDYQTDAK
                     LRARLKKETTESTVLIVAQRVGTIMHADKIIVLNEGEVVGMGTHRELLEKCPIYYDIA
                     ASQLSKEELA"
     gene            9211..9423
                     /locus_tag="ACG8LA_002477"
     CDS             9211..9423
                     /locus_tag="ACG8LA_002477"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit epsilon"
                     /protein_id="HFQ0204753.1"
                     /translation="MIYKVYYQETKVRNPKREETKSLYIEAKSDVDARQRVEENTPYN
                     IEFVQLLEGSHLEYEKENADFSLVEF"
     gene            9425..11104
                     /locus_tag="ACG8LA_002478"
     CDS             9425..11104
                     /locus_tag="ACG8LA_002478"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HFQ0204754.1"
                     /translation="MKLSIKNNETGVFAIGGLGEIGKNTYGVQFQDEIILIDAGIKFP
                     EDDLLGIDYVIPDYSYIIQNLHKVKALVITHGHEDHIGGIPYLLKQANIPIYAGPLAL
                     ALITNKLDEHGLLRDAELHEINEDTIIRFRKTSVSFFRTTHSIPDALGIVVKTPSGNI
                     VATGDFKFDFTPVGEPANLHKMARIGEEGVLCLLSDSTNAEIPTFTKSEKTIGHSILK
                     IFSKIEGRIIFASFASNIFRLQQAADAAVATGRKIAVFGRSMENAIVNGQRLGYIKVP
                     DGTFVDAHEINRLPANETMILCTGSQGEAMAALSRIANGTHRQIQIQPDDTVIFSSSP
                     IPGNTTSVNHLINLLSEAGAEVIHGKINNIHTSGHGGQEEQKLMLRLMKPKYFIPVHG
                     EFRMLKVHASLAQDVGVPAENCFIMENGDVLALTSDSARPAGHFVAGDVYIDGSGIGD
                     IGNVVLRDRHLLSEEGLVLAVATVDIKKKEILAGPDILSRGFVYMRESGEMINEAQRI
                     LFHALRECLNGPDCSEYKLKEAMTGALQPFLFERTERHPMILPMVMTPDEE"
BASE COUNT         3266 a         2429 c         1971 g         3589 t
ORIGIN      
        1 ttaaaaaaat aaaattttat tggttttttc ttaaccattt tgaattggtt tttgcaaacc
       61 ctttaacttc atattcgttt gtttcttcca tgtacgcttc gtccaaaacc attgtttgtc
      121 ttctcaactc gcttaatttc tgtccttcgt tgcttggcac agaaagtgta taaggggtca
      181 ttagttccat cagctgacgt ttgattgctt cgatcaacgc catcttacct tctttcgtct
      241 gagtagaaat caatacattt gggaatagcg taggcgtgaa catcgctggg tcgatctggt
      301 ctgccttatt gtaaacagtc agtatcggca tttctttcat attcagttca tccatcaatt
      361 ttaagacagt ctgctcctgt aaaatacgat ctggagaact agcatcgact acatgtagca
      421 aaagatccat attttgactt tcttctaatg tagaatggaa agcatcgatc agttgcgtag
      481 gcaggtcttg gatgaacccg acggtatccg ttacagtaat ctcaaatcct tcagcaaaac
      541 gccatctctt agtcaatgga tctaacgttg caaacaattg atctttcgaa taagtatccg
      601 cttgtgtcaa tagattcaag atagttgact tcccggcatt cgtgtagcca ataagtccaa
      661 tctgaaaaat ctcgctattt tttctttttt ggcgattgcg ctctcgatga gcttctactt
      721 ctttcaattc tttcttaaca gcaaaaattt tattccgtat atgtcggcgg tctgtttcta
      781 actttgtttc acctggccct cttgttccga tcccaccgcc aagacgagat aatgttttcc
      841 cttgccctac taaacgaggc agcaggtatt ctaactgagc aagttcaacc tgcagcttcc
      901 cttctttcga acgagcacgc atcgcaaaaa tatctaagat aagctgcacg cgatcaatta
      961 ccggaagacc aacagcatcg gtaatcagtt ggctctgtct cggagttagc tcatgattaa
     1021 agatgatcaa atccgcttca tgcgcatccg cttgttgaac taattcttgt aatttccctt
     1081 taccgataat cgtttgccga tccacttgtg gtctcttttg tgtaattgtg aatacgactt
     1141 ctcctgatgc ggtattcgtc agctgaacta gctcttccat tgactctgaa aagtaacgct
     1201 ggtttgcttc ggtttctacc cctacgatga tcactttttc ttccatttta ttccgcctcc
     1261 agccattttt tgattgtttg ctcaatctga cttttttgat ttggctcact tataagatca
     1321 aaccactgtg catccaaacg gttacgaaac cacgtcaact gacgtttcgc gtatcttctc
     1381 gaatgtagtt tgacttgttc tgttgcttct tccaatgttt ctttcccttc aaaataaggg
     1441 aaaaattctt tatatccaat accttgactg gcctggactt ctccaagctc atacacctta
     1501 cgcgcttctg ctactaaacc ttctgctagc atcaaatcga ctctttgatt gattcgttca
     1561 taaagaatac tacgcttcgt atctaatcca atcatgaggt aatcatacaa ttgctttggc
     1621 tcttctttag gtgccgtgat actatgtcct gtcgtctcta aaacttccag agctcttatc
     1681 actttgcgtt gattgttcca gtggattttc tcagcagctg ccgggtcttt ttctttcaac
     1741 tgattccata atgcttggga accaattgtt tcagctaacg tttcatactt ttttctaatc
     1801 tcaggattcg cttcttctgt cgctcctaac tgataatcat atagaaggga ttggatatag
     1861 agacccgtac caccagctat gataggtagg tgccctcggt tcgcaatctc ggtaatcaat
     1921 tgtcgacctg aatgctgaaa atcagcggct gagtaacgtt gagtaggttc gatcacatca
     1981 atcaaatgat gcggaacatt attcatctct tcttctttga tttttgctgt accgatatcc
     2041 agatttttat agatttgcaa tgaatcacca ctgatgatct ctcctccaaa tagttgtgcg
     2101 agttccacac ttagcgctgt tttaccgact gctgtcggac cgacgatcac taatactttt
     2161 tccatatttt acctactttt cgttgattgt ttccaccgaa gagctttctc cggaaaatca
     2221 gttattattc catctatttt gagttcttga catttggcca tttcttcttc atcgttaatc
     2281 gtccatgcac gaattgcttt tggaaaatca gctgcctgga ctggatgttc gaacaaccaa
     2341 gtattttttg gatgtactcc ttctatataa ggggtttctg ctgctagttg gatcttttta
     2401 tcagaagtac tcatcaataa gtccagctgt atctccggtt ccagtaatgc gattttttcc
     2461 aaagaatcca aatgaaagct gcaatatgca tgttgaaaag gccaatctct actttttaat
     2521 gtttcggcta atttttcttc gataccggga tattcatact gatcagtttt aatttcaatc
     2581 attagcatcc ctcggtaatt tttttggagg agcagtccta acacttctct caattcagga
     2641 actttagctg ctggaaattc tttgctgaat ttgccccctg cattcaattt tttgagttct
     2701 tccaatgttt tttctcgaat cagcccttta ccgttagtcg tccggtccac ttcttcgtcg
     2761 tgcataacga tcaaataacc atctttgctt agatggacat ctagttcgat accatctgca
     2821 cctactcgta cagcttctgc aaatgcagga agcgtatttt ctgggtgggt gccgctgctt
     2881 ccgcgatggg catagatttg taacatcttt cttcactccg ttcagttcta ttgtatcatt
     2941 aagaaaaaaa gaaagcatta ccacgctctc atgtgcaacg gcaatgcttc aaaatatcag
     3001 ctccaaacat catctttcga gaagaaacca atcggctggc gcgtcatagt cttcaactga
     3061 gctttttttt cattgatcat ttcagtcaga ctatccgtaa aattctctaa aatcacgcgt
     3121 ccgcctttat aagcatatcc accaatcttc attgtttcat ctggagataa aatcactttt
     3181 cgatgggaga tattcttaaa tagctcgtct aaaatataat ttggcagata aaaactattt
     3241 tgcgctgaaa atgattggag atacgcaaaa tcgtcaatcg tgatataaca atcatcaaat
     3301 gcatcaaagc tgacatattc ttccatcagc gttgtccgtt tttgcaagat ctcgttgatc
     3361 tttttattta attgattcag cgtctcgatt tctttgactt tcaattccaa ttcacgtcta
     3421 cgctgttctt tattttccaa gtgacgcatt tgcagtatca tgccgatata gacaactaca
     3481 gcacctgtca gcactccgat aaggccagta ataccaacta tcaatctgtt gttcctcctt
     3541 gttttgtttc tctgcttatc ataccataaa gcgggtttat gcgactaatt tgcctaagtt
     3601 ttttatttga ccttttttga ccaaaaatgt atactacatt ttaggtatta gaaactaaat
     3661 tatggtacac tatttctaaa cgaaatcaag gaggaactct attatgaatt taattcctac
     3721 agtcattgaa caatcttcac gaggtgaaag agcttacgat atctactcac gtttattgaa
     3781 agaccgtatc atcatgttaa gcggccaagt aacagatgat cttgctaatt cgatcatcgc
     3841 ccaattgctt ttcttagacg ctcaagattc tgaaaaagat atctatcttt atatcaattc
     3901 tcctggtggt tcagttacag caggtatggc tatttacgac acaatgaact ttgtcaaagc
     3961 agatgtccaa acaattgtta tgggtatggc tgcttcaatg ggaagcttct tgctgacagc
     4021 tggtacaaaa ggtaaacgat ttgctttacc aaatgctgag atcatgatcc atcaacctct
     4081 tggcggcgct caagggcaag caactgaaat cgaaattgcg gcacgccata ttttgcaaac
     4141 acgcgaacgc ttaaacaaaa ttttagctga acgcactgga caaccgcttg aagtgattga
     4201 aaaagataca gatcgtgaca actatatgac agctgaacaa gcaaaagcat atggattgat
     4261 cgatgaagtc atggaaaaca gttcttcatt aaattaatct gtttcaaagg aagctttttt
     4321 aagctctctt atctaaacca aataaaaaag gatggtcaac tcaaactgac catccttttt
     4381 tattttatgg atgctactgc ctatctttgc tccttgaatt ttccttgcgc atgcatccga
     4441 cctatctcga cataatgctg gatgttttct ttgttttttt gtatttcttc ttttgtcaaa
     4501 ggacggatca ctttagctgg gcgaccaaaa gccaagacat taggaggaat aacttttcct
     4561 tctgttacta atgatccagc accaatcaaa ctattctcac caataaccgc atgattcaat
     4621 atcgtggtcc ccatcccgat cagcgcccct ttttcgattg tacagccatg tagcatgcac
     4681 tgatgtccta ccgtcacatt ctccgcaata tctacaggtg catcatgatc gacatggatg
     4741 attgtaccat cttggatatt cgttctttgt cctattttta tccaattact gtccccgcgt
     4801 aaaacagctt gataccagat cgtcacatct tctgacaatg tcacatcacc aatcactgtg
     4861 gcatttgatg ctataaaccg ttccatattt atttttctcc tttcattttt tgtagaaact
     4921 aatcctattg aataaaggta tcatagcata tatttatttc ataagaaaaa aaacaggtaa
     4981 aacctgctca ggccagatgt ctatttacag tatctggtaa ctgacgtttt acctgttttt
     5041 attgtacatc tatattttct tctattactt tttttaaaat taattcgtac acttctattt
     5101 gtgctgccaa gcgttcgatt tgaaactcat tttcaaaaaa atcagctgaa tcaaaaggct
     5161 tcgtctgaca gacgtgcgtt aaacgatcaa cttctctttt ggcttcagta attttttcat
     5221 ttaaaaactg ttccatctcc gtgtcctcac ttttcttgat aactttactt taccattatc
     5281 aagaatagag aacaaaaaat aagttttaaa ctgttttatt cttatatgac ttattctgct
     5341 tcctcagcaa attggctgtt atacagtttt tcataaaatc caccttgtgc caataaactc
     5401 tcatgcgttc ctttttcaat gatctgacct tgatccatca ctagaatcag atctgcatca
     5461 cggattgtcg ataaacggtg agcgatgacg aaacttgtcc gtccctccat cacgcgatcc
     5521 attgcttttt gaatcaacgc ttctaaacgg gtgtctactg aacttgttgc ttcatctaaa
     5581 atcaagattt taggatcgga gaccactgct cgggcaatcg tcagcaactg tttttgtcct
     5641 aaagacacat tgtctccctc agaattgatg gccatatcat atccatctgg catcgttcgg
     5701 ataaaatgat ctacgtttgc tgttttcgca gcatcaacta cttcataatc tgtcgcatca
     5761 agctttccga agcggatatt atctgcaatc gttccttgat aaagccatgc atcttgcaag
     5821 accataccaa atagcgaacg cacatcactg cgactcattg atttggtgtc gattccatca
     5881 atccttattg ctcctttgtc tacgtcataa aaacgcatca atagattgat caatgtcgtc
     5941 ttgccggcac cggtcggacc gaccacagct acggtttgac cagctttcac ttcaaaattc
     6001 aaatcttgga ttaatggttt cttcggatca tatgcaaaat cgacatgatc gaatgtcaca
     6061 tctcctaaaa tcgtttctgg cagtgaagca tctactttgt tttctttttc ttctggctca
     6121 tctaaaatct cgaatacacg tttcgttgcc gctgatgcac tttgcaaaac tgaagacaat
     6181 tgtgtcacgt tccccattgg ctgactgatt tgccaaatat attggatgaa tgcttgtagt
     6241 tgaccgacaa cgatcgcccc agtaataaca taaaagcttc ctagaacagc cataccaata
     6301 taagtagcat aggcagttaa ttgaactaga ggcatcatca agccagaaat gaatgctgca
     6361 cgaaacccaa agtatttcaa gctgtgatta acttttttga atccttccaa tgtttctttt
     6421 tcgcgtccat atactttcaa tacactaaaa cctgtcatat tttcttggac gtagccgttt
     6481 agctcaccaa gagaattctg catgctttga aaatatttct gcgaagcatt gatcactcgt
     6541 tttgagatcc agatcgatgt tggaatcatg atcatagaga tcagcgccat catcggctgg
     6601 atataaaaca tcattgctgc agccaacgta attcccaata tcgcatttac gataccaata
     6661 aaagcttgtt gtaaagcacc gctgactgca tctacatcat tcgtcacacg agacaaaata
     6721 tttccttgct ggtttttatc gaaatatgaa accggaagac gattgatttt ttcttctatg
     6781 tctcttctca aatcatgcat ggcactttga acgacatttg tcatcaaaac accagaaagt
     6841 aattgcgaaa tacaataccc tattccaaca actgtgatcc aaatgagaca tttgaatata
     6901 taagaaaaat tgattgattc gccattggca atattacggc tgatttctgt agtaggaagt
     6961 cctgtaacat atggcaaagc cacgttgaaa gccactgtca gaactgtaaa taggatcact
     7021 aaaagaaaag tctcacgata cggtctgata tatcgagcta aacgttttaa ggaagaaaag
     7081 gtttttttca tgctaattcc tcctttgata attgagaagc ggcaatatca taataaatcg
     7141 ggcatttttc caacaactcc cgatgcgtcc ccataccgac gacttctcct tcatttaata
     7201 cgatgatctt atctgcatgc atgatcgttc ccacacgttg tgctacgatc aatacagtag
     7261 attctgtcgt ttcttttttc agacgagcac gtaacttcgc atccgtttga taatctaatg
     7321 cagaaaagct gtcatcaaaa atatagattt ccggacggcg tatgatggct ctggctattg
     7381 ccaatcgttg tttttgtcca cctgaaaaat tggaaccacc ttctgataaa tgttcattaa
     7441 atccatctgg ttttcgagaa atgaattctg aagcttgagc aatctcagct gcacgttcca
     7501 tttcttcttg cgtagcatct tctttcccgt atcgcaaatt atctgcaatc gttccagtaa
     7561 atagcagcgc tttttgcgga ataaacccaa tcttatctcg caacttgctt agccgataat
     7621 ctctcacgtc tactccatcg atcaagatct ttccttcact cacatcataa aagcgaggga
     7681 tcaattggat caacgtagat tttccgctac cggtacttcc aataaaagca acggtctctc
     7741 ctggagaggc tgtaaaactg acatttcgta tcactggctc ttgcgaatgg cctggataag
     7801 caaatgttac attttgaaat tcgatatacc ctttagtttt tgtatcagat ataccatttg
     7861 gatcttctac aatcgaaggt ttggcatcta gggcttcttg gatacgtcca gctgaaacag
     7921 ctgctcttgg atacatcatg aacacactag caaataacat gaatgagaac aaggcatgga
     7981 atatatactc gataaacgca atcaaatctc ctacacgaag ctcgcctgca tcgatttgca
     8041 ctgccccgct ccagatgatc aataccatta cgatattaaa taagaaataa aaacccggtt
     8101 gtgcaacagc catcaaacgg aataagcttt ttgaactaga agcataattc tcattgacta
     8161 cagcaaaacg tttttcttca aacttttcat tgacgaatgc acgaatcaca cgcaatcctg
     8221 aaagattttc ccgcaagata ctgttgattt tatctaagtt tttttgttgc tttttagata
     8281 acggttcaga caccttagca atcgctacga ctgccaataa tagtaaaggt aatgcaccta
     8341 ctacatacaa actgagtgtc acacttgtac gcatgaccat gtacaaactg acaatgaaca
     8401 tcattggtgc cataaaaccg atacgtaaaa tattttgcag gaacaacatg atctgataag
     8461 catcgtttgt tgtacgagtg atcaatgaag atacgcctag attttcgtat tcctgatgcg
     8521 aataactttg gatcttttcg aacaaatcat ctcgaatatc tgctacgata ttagtcgtaa
     8581 tcctcgaacc aaaataacct aacaagatat tcaaaataat accgattaca gtaataacga
     8641 tcataaatat cccttgttgc ttcacataat caaaatcatc attgcggatt cctacatcga
     8701 tcatacgtgc taaaatcgta ggaagtccta attcaatcaa aataaaacca aatacgcata
     8761 tgaaattgaa aaacaagaat ttcttataac gcatggtata atgccacatt agtttcactt
     8821 tctcatctcc ttttaatctt ttgttacatt ttcattacta aaaatgatag cacaacgagc
     8881 ctattaatag aacacttctc tcataaaaaa gtcattatga ttatagcggg atgataaaca
     8941 ttgatttttt ctttcaatct agttgatttc tatacttatt tgctgtttta tgctagaata
     9001 acaattaatt gttgtatatt ttttatacag aaggtacggt tgaaaaaata tccgaacaga
     9061 taagcaaaaa cgaggcttgt ctctttgact cgaatccagt attctagtca aagcatatga
     9121 aaaaccaggt ggcttgtccc ctcgttttgt gttgtctaaa aaaatcaact agctaaatca
     9181 ctgctttacg cagataaagg agacaaaaca atgatctata aagtttatta tcaagaaaca
     9241 aaagtacgca accctaaacg ggaagaaaca aaatctcttt acattgaggc aaaaagcgat
     9301 gtagacgctc gccaacgtgt ggaagaaaat accccataca atattgaatt cgttcaactt
     9361 ctagaaggaa gtcatctaga gtacgaaaaa gaaaatgctg atttctcatt agtggagttt
     9421 taatatgaaa ctttccatca aaaataacga gacaggcgtc tttgctattg gtggattagg
     9481 tgaaatcggg aaaaatacgt atggggtaca attccaagat gaaatcattt tgattgatgc
     9541 cgggatcaaa ttcccggaag acgatttact tggaattgac tatgtcattc ccgactacag
     9601 ctacatcata caaaacttac acaaagtaaa agccttggtg attactcacg ggcacgaaga
     9661 ccacatcggc ggaataccct acttgctgaa acaagcaaat attcctatct atgctggtcc
     9721 tctcgcatta gcgttgatca caaacaaatt agatgagcat ggcttgcttc gagatgcaga
     9781 gctccatgag atcaatgaag atacgatcat ccgttttaga aagacttctg tcagcttttt
     9841 cagaacgacc catagtatcc cagatgcatt agggatcgtg gtgaaaacac cttctggaaa
     9901 tatcgtagcg actggagact tcaaattcga tttcactcct gttggcgaac cagcaaactt
     9961 gcataaaatg gctcgtatcg gggaagaagg agtcttgtgc cttttatctg atagtacaaa
    10021 tgctgagatt ccaacattta ctaaatcaga aaaaacgatt gggcattcta ttttgaagat
    10081 cttttcaaaa atcgaaggac gtatcatttt tgccagcttt gcttctaaca tcttccgttt
    10141 gcagcaagca gcagatgccg ctgtggcaac tggtcgtaaa atcgctgttt tcggacgaag
    10201 catggaaaat gccatcgtca acggtcaacg tttaggatat atcaaagttc cagacggcac
    10261 atttgtagat gcacacgaaa tcaatcgctt gcctgccaat gaaacgatga tcctatgtac
    10321 aggttctcaa ggagaagcga tggccgcgtt gagccgcatc gcgaatggta ctcaccgtca
    10381 aatccaaatc cagccagacg atacagtgat cttttcaagt tcacctattc ctggtaatac
    10441 aacaagtgtc aatcatttga tcaatttgct gtctgaagct ggtgcagaag tgattcacgg
    10501 aaaaatcaat aacatccata cttccggtca cggtggacaa gaagaacaaa aattaatgct
    10561 tcgtttgatg aagccaaaat attttattcc tgtccacgga gaattccgca tgttgaaagt
    10621 acatgcttct ctagcacaag atgtaggtgt tcctgcagaa aactgcttca tcatggaaaa
    10681 tggcgatgtt ttagcgttaa ctagcgattc tgcgcgtcct gctgggcatt ttgtggctgg
    10741 agatgtgtat atcgatggta gcgggatcgg tgatattggt aatgtcgttt tacgtgaccg
    10801 tcacctgctt tcagaagaag gtcttgtatt agctgtcgcg acagtggata tcaagaaaaa
    10861 agaaatcttg gctggtccag atattctctc tcgtggattt gtctacatgc gagaatcagg
    10921 agaaatgatc aatgaagctc agcgaatctt attccacgct ttaagagaat gtttgaatgg
    10981 acctgactgt tcagaatata aattgaaaga agcgatgact ggcgcgcttc agcctttctt
    11041 attcgaacgt acagaaagac atccaatgat tttgccaatg gtaatgacac cagatgaaga
    11101 ataaataaga ggttatgaaa tcagcacctt gtcctgaata taagagaaaa caaatgaaaa
    11161 acatgagaag ccatttttgt ttgttcttat tccttgatac aaggtggctc tttcatagcc
    11221 tcttaaattt atttactttt tcatacaaaa aaata
//
LOCUS       DAZKKZ010000080        11099 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.082, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000080 DAZKKZ010000000
VERSION     DAZKKZ010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11099)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11099)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11099
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.082"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(14..979)
                     /gene="nrdF"
                     /locus_tag="ACG8LA_002479"
     CDS             complement(14..979)
                     /gene="nrdF"
                     /locus_tag="ACG8LA_002479"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA];
                     GO_function: GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA];
                     GO_process: GO:0009263 - deoxyribonucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HFQ0204755.1"
                     /translation="MSETYYEAINWNEIEDIIDKSTWEKLTEQFWLDTRIPLSNDLDD
                     WRTLSQLEKDTVGHVFGGLTLLDTVQSESGMDQLRKDVRTPHEEAVLNNIQFMESVHA
                     KSYSSIFSTLNTKKEIEEIFDWTNTNPYLQKKAERINEIYKHGTPLEKKIASVFLETF
                     LFYSGFYTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEAEQETL
                     KDWMYNLLYELYENEERYTEELYDPIGWTEEVKTFLRYNANKALMNLGMDPLFPDTAN
                     DVNPIVMNGISTGTSNHDFFSQVGNGYLLGHVEAMKDDDYLIGLE"
     gene            complement(1029..3188)
                     /gene="nrdE"
                     /locus_tag="ACG8LA_002480"
     CDS             complement(1029..3188)
                     /gene="nrdE"
                     /locus_tag="ACG8LA_002480"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HFQ0204756.1"
                     /translation="MSLKNLQDVSYFKLNNEINRPVNGQIPLNKDKEALVAFFEENVK
                     PNTMTFPSIMEKINYLIDQEYIEAEFIQLYSPSFIEKLYQFLDEQHFSFKSFMAAYKF
                     YSQYALKTNDGSAYLETYEDRVAFNALYFANGDEELALALADEMIHQRYQPATPSFLN
                     AGRKRRGELVSCFLTQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSAKKENADEKIR
                     VKTLSLGVIVPDKFYELTRKNEDMYLFSPYSVEKEYGVPFSYVNITAEYDHLVANPNI
                     RKQKIKARDLENEISKLQQESGYPYVINIDTANRENPIDGKIIMSNLCSEILQVQTPS
                     VINGKQEYEVLGTDISCNLGSTNIVNLMQSPNFGQSVRTMTRALTFITDASDIDVVPP
                     IQNGNKLNHTIGLGAMGLHTYLAKEQMEYGSEDSLDFTNIYFMLLNYWTLVESNNIAR
                     ERKQVFHNFEKSAYADGTYFEKYVTGEFQPKSEKVKALFEGIFIPTAEDWNALKQAVM
                     KDGLYHQNRLAVAPNGSISYINDTSASIHPITRMIEERQEKKIGKIYYPAPYLSNETI
                     PYYTSAYDMDMRKVIDVYATAQQHVDQGMSLTLFMRSEIPEGIYEWKTTTKQTTRDLN
                     ILRHYAFHKGIKSIYYVRTFTDDAEEIGSNQCESCVI"
     gene            complement(3347..3571)
                     /gene="nrdH"
                     /locus_tag="ACG8LA_002481"
     CDS             complement(3347..3571)
                     /gene="nrdH"
                     /locus_tag="ACG8LA_002481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HFQ0204757.1"
                     /translation="MNVKIFSKNNCMQCKMVKRFLTENQIAFEEVNIDEQPEAVDWLK
                     AQGFQSVPVITSDAETVIGFRPDQLRKLAS"
     gene            3972..4445
                     /locus_tag="ACG8LA_002482"
     CDS             3972..4445
                     /locus_tag="ACG8LA_002482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HFQ0204758.1"
                     /translation="MQTLAQAKQNFVYQVERIETEEKTKRHLQNIGIVAGSKIVVVNL
                     SGNNAILLVKSHRVAVSREILGQIFVNKKTASSESWTSLDQLKAGETGIVVAIHGQGA
                     VKRRLMDMGLTRNVKIVIRKLAPLGDPIELTVRGYELTLRKSEAELILIQREEKE"
     gene            4442..6574
                     /gene="feoB"
                     /locus_tag="ACG8LA_002483"
     CDS             4442..6574
                     /gene="feoB"
                     /locus_tag="ACG8LA_002483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0015093 - ferrous iron transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HFQ0204759.1"
                     /translation="MNIALVGNPNSGKTSLFNLLTGSNQYVGNWPGVTVEKKEGSLKK
                     NPNIHIQDLPGIYSLSPYTPEEVIARDYLVQEQPELIINIIDATNLERNLYLTTQLLD
                     LDIPMIIGLNMMDVIKKEGKKINLEKLSYGLGVPVLPISVLKKQGIEKLIEKIQESAK
                     KRPSIPVPCTYDPRLEAALHEIEDVLGEQSGKKRWYAMKYFERDQKVREDYEIAVSQQ
                     KEIEQLIQLTEKLLDDDSETILVNERYEFITQLCTLCVVSNDSFQLSMSDKIDQIATN
                     RWLALPIFAFVMWLIYYLAIQTVGTMGTDWINDTLFGTWLPEHVGRLLAEWQVAGWMQ
                     ELILNGIIAGVGAVLGFLPQLIILFLCLSFLEDCGYMARIAFVMDRLFRKFGLSGKSF
                     IPMLIATGCGVPGVMASRTIENEQDRRLTIMVTTFMPCSAKLPIIALVAGAFFPHQSW
                     VAPSAYFLGMTAIIFSGISLKKTRLFAGDTAPFIMELPAYHFPQWSAVLRQTYDRSKS
                     FVKKAGTIIFVSSIVIWFSSSYNFYAQPVSEDQSILAFFGRILAVVFQPLGWGNWQGT
                     VAAITGLVAKENIIGTFGILFGHAEVSENGREIWQVLQHTYTPAAAYSLLAFNLLCAP
                     CFAAIGAIHREMNAKKWTWIAIGYQCGLAYLVSFVIYQLGHLLEGGQVALGTYLAILL
                     MIGLVYVLFRQPKSKNQFYTILSLEGEE"
     gene            6576..6710
                     /locus_tag="ACG8LA_002484"
     CDS             6576..6710
                     /locus_tag="ACG8LA_002484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="HFQ0204760.1"
                     /translation="MATFLLSVLIFGSAGAIVYTRLKSGKNCDDCQTACPVKKEQIKR
                     "
     gene            6804..7448
                     /locus_tag="ACG8LA_002485"
     CDS             6804..7448
                     /locus_tag="ACG8LA_002485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFQ0204761.1"
                     /translation="MSGKKKIVRPRYQQIAVDLAERIVENRYKVGEKIHARSTLASTY
                     NASPETTRKAINVLVDLGIMEVRHGSGAFVASKEKAKDFLLQYQDVQSIQDTKAEIMA
                     SVEKQQDELNHFSQLLDQLVNQTKRIHKMNPLLPFELSLSEKAMHLDRSISELNIWQA
                     TGATVIAISHNEELLVSPGPYAKFTAGDIVHFIGNEYTLQRMTNFFYPEHQLAE"
     gene            7635..8828
                     /locus_tag="ACG8LA_002486"
     CDS             7635..8828
                     /locus_tag="ACG8LA_002486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     ATP-binding protein"
                     /protein_id="HFQ0204762.1"
                     /translation="MVKVEVKHLTKIFGKKTQAALDMMNDHQPKTEILKKTGATVGVY
                     DVNFDVKEGEIFVIMGLSGSGKSTLIRLLNRLIEPTSGSIYIDGEDVSKLSKEELREV
                     RRHKINMVFQNFGLFPHRTILENTEYGLEVRGVPKEERQEKAEKALENSSLLSFKDQY
                     PSQLSGGMQQRVGLARALANDPEILLMDEAFSALDPLIRREMQDELLDLQANVQKTII
                     FITHDLNEALRIGDRIALMKDGEIMQIGTGEEILTNPANDYVREFVEEVDRSKVLTAQ
                     NIMVPALTTNIESDGPNVALTRMRNEEVSMLMAVDRKRHLKGIITADQALEARKQKRP
                     LIDFLDENVTVIGKDMVVSDIFNIIYDSPTPLAVVEDGKLKGVVIRGSVIEALAETSE
                     VSEHE"
     gene            8821..10548
                     /locus_tag="ACG8LA_002487"
     CDS             8821..10548
                     /locus_tag="ACG8LA_002487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate binding
                     protein"
                     /protein_id="HFQ0204763.1"
                     /translation="MNNLLNYQLPVANWVENITEWFTTTFSGLFSFLQTIGQAVMSGI
                     TNLLLVIPAPLFILLLTVAAFFISKKRPGLTLFTLIGLWFIYNQGLWNDLMNTVTLVL
                     LSSVISIIIGVPLGILMAKSSKAQSIIKPILDFMQTMPGFVYLIPAVAFFGIGMVPGV
                     FASVIFALPPTVRFTNLGIRQVPKELVEASDSFGSTSRQKLFKLELPLAKSTIMAGIN
                     QTTMLSLSMVVIASMIGAPGLGRGVLSALQRAQVGNGFVNGVALVILAIIIDRFTQHL
                     NQPNNKKAAGATTQKSKKRQGLIIGAVVVVILGAIGIGSFSSAKETKRINLSYVEWDT
                     EVASTNVVGEVLKQMGYDVTMTPLDNSIMWKSVSNGESDAMVSAWLPKTHGSQYAQYK
                     DQVEDLGANLTGAKVGLAVPAYMDVNSIDELTDQAGKKIIGIEPGAGVVTAAENTIQK
                     YDNLKDWKVETSSSGAMTVALGQAIKKHEPIVVTGWTPHWMFAKYDLKYLEDPENGMG
                     SEEQIHTMVRKGLKEDQPEAYKVLDNFHWSEKDMEKVMLEINNGKDPQQAAKDWIKEN
                     QELVESWKK"
     gene            10942..>11099
                     /locus_tag="ACG8LA_002488"
     CDS             10942..>11099
                     /locus_tag="ACG8LA_002488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II bacteriocin"
                     /protein_id="HFQ0204764.1"
                     /translation="MKHLKILSIKETQLIYGGTTHSGKYYGNGVYCTKNKCTVDWAKA
                     TTCIAGMS"
BASE COUNT         3486 a         1963 c         2310 g         3340 t
ORIGIN      
        1 ttaaaataaa tccttattcc aatccaatca aataatcgtc gtctttcatc gcttctacat
       61 gacctaacaa atagccgttt ccgacttgtg agaagaagtc atggttgctt gtgcctgttg
      121 aaatcccgtt cattacgatt gggttgacat cattggcagt atctggaaag agtggatcca
      181 tccctaggtt catcaatgct ttgttggcat tatagcgtag gaatgtcttg acttcttctg
      241 tccagccgat tggatcgtat aattcttctg tataacgttc ttcgttttcg taaagctcat
      301 aaagaagatt gtacatccag tcttttaacg tttcttgttc tgcttcaggt aactcgttga
      361 atcctaattg gaatttgtaa ccgatgtagg ttccatgtac agattcatct cggatgatta
      421 gtttgatgat ctctgctacg ttagccaatt tgttgtttcc taaataataa agaggagtat
      481 aaaaacctga atagaacaag aatgtttcta aaaagacgct ggcaattttc ttttctagcg
      541 gtgtaccgtg tttgtagatt tcattgatac gctcagcttt tttttgcaga taaggattcg
      601 tatttgtcca gtcaaaaatt tcttcgattt cttttttcgt attcagtgta ctaaaaatag
      661 aagaataact tttggcatga acggattcca tgaattgaat attgttcaaa acggcttctt
      721 catggggagt gcggacatct ttacgcaact gatccatgcc actttcagat tggacagtat
      781 ctagcagtgt caaaccgcca aatacatgtc ctactgtatc tttttccaat tgagacaatg
      841 tacgccaatc atctaggtca tttgaaagtg ggatacgtgt atctagccaa aattgctctg
      901 tcagcttctc ccaagtggat ttatcaatga tatcttcaat ttcattccag tttattgctt
      961 cataatatgt ttctgacatg agaatgctcc tttaattaaa atatgaataa gcgaatctat
     1021 ctatgatatt agatcacgca gctttcacat tgattgcttc cgatttcttc tgcatcatca
     1081 gtaaaggtac gtacgtaata aatggatttg attcctttgt ggaaagcgta atgtcttaaa
     1141 atattcaaat cacgtgtcgt ttgcttcgtt gttgtcttcc attcataaat gccttctggg
     1201 atttcagaac gcatgaataa agtcaaactc atgccttgat cgacgtgttg ttgtgccgtt
     1261 gcataaacat cgattacttt acgcatgtcc atatcataag cagaagtgta atacggaatc
     1321 gtctcattgg atagataagg cgctgggtaa taaattttac cgattttctt ctcttggcgt
     1381 tcttcgatca tgcgagtgat aggatgaata cttgcactcg tatcgttgat atatgaaatt
     1441 gagccatttg gtgctactgc caagcgattt tgatgataca gtccatcttt cattactgct
     1501 tgtttcaaag cattccaatc ttcagcagtt gggataaaaa tgccttcaaa caatgctttg
     1561 actttttctg attttggctg gaattctcca gttacgtatt tttcgaaata agtgccgtca
     1621 gcataagctg atttttcaaa attatggaaa acttgttttc tttcacgagc gatattgttg
     1681 ctttcaacaa gtgtccaata attcaacagc atgaagtaaa tatttgtaaa gtctaatgaa
     1741 tcctctgagc catattccat ttgttctttt gcaagataag tgtgtaagcc catggcacct
     1801 aatccaatcg tatgattcag cttatttccg ttttggatcg gtggtacgac atcgatatca
     1861 gatgcatctg taataaatgt caatgcacga gtcatcgtac gcacagattg accaaagtta
     1921 gggctttgca tcaaattcac gatatttgtc gagcctaagt tacatgagat atctgttcct
     1981 aatacttcat attcctgttt gccgttaatc acagaaggcg tttgaacttg taaaatctct
     2041 gaacataaat tactcatgat gatcttgcca tcgattggat tctcgcggtt cgctgtatca
     2101 atattgatta cgtaaggata gccagattct tgttgtaatt ttgagatttc attttcaaga
     2161 tcacgcgctt tgattttttg tttgcgaatg tttggatttg caactagatg atcatactca
     2221 gctgtaatat ttacataaga gaatgggaca ccatattctt tttcgacact atatggacta
     2281 aataaataca tatcttcgtt tttacgtgtc aattcataaa atttatcagg tacgatcacg
     2341 ccaagagaaa gagtttttac gcgaatcttt tcatctgcat tttctttttt tgctgaaagg
     2401 aaagcaataa tgtctggatg gaaaacgttc aaataaacca cgccagctcc ttgacgctga
     2461 cctaattgat tagaatagct gaaactatct tcgaataatt tcatgactgg aacgacacca
     2521 cttgcagcac cctcatatcc tttgatagga gcgccggctt cacgaagatt tgataaagta
     2581 atccctacgc cgccaccaat acgggacaat tgcaaagcag agttgattga gcgcccgata
     2641 gagttcatat cgtcagtgac ttgagtcaag aaacaagaca ccaattcgcc ccgacgttta
     2701 cgtccagcat tcaagaaaga aggtgtagct ggctgatatc gttgatggat catttcgtct
     2761 gcaagagcaa gtgctaattc ttcatccccg ttcgcaaagt aaagcgcatt gaaggctact
     2821 cgatcttcat aagtttccag ataagcggaa ccgtcgttgg ttttcaacgc atattgagaa
     2881 taaaatttgt aagcagccat aaaagatttg aaagaaaaat gttgctcgtc caaaaattga
     2941 tatagctttt caataaatga tggtgaatac aattgaatga attctgcttc tatatattct
     3001 tgatcgatca agtaattgat tttttccata atagatggaa aagtcatcgt atttggtttg
     3061 acattttcct caaaaaaggc aactaaagct tctttatcct tattcaaagg gatttgacca
     3121 ttgactggcc gattgatttc attattcagc ttgaaataac tgacatcttg taaattttta
     3181 agactcatac gtacgcccaa ccttcatttc gtatttgatg atgcttgatt gcaaatcatt
     3241 gcattgtttt taagctttaa aaaaggattt ggaagtttgc gacaaaaact ggtgctgtct
     3301 caagcccttc aaatccatgt atcacgtttt gattctttta gtcatgttag ctggcaagtt
     3361 tacgcaactg atcaggacgg aatccgataa ctgtttctgc atcagaagta atgacaggaa
     3421 cactttggaa tccttgtgct ttcaaccagt ctactgcttc aggctgttca tcgatattga
     3481 cttcttcaaa agcaatttga ttttctgtta aaaaccgttt gaccatctta cattgcatac
     3541 aattattttt agaaaagatt tttacgttca tggtgagtgc ctcctctaac acattcttat
     3601 tatctataat agatagtata aaactcttag taaaaaagtc aaacaacaaa cactacatat
     3661 tgtgttgtgg aaactgtgga atactaagtt ttgtgttttt gaaaaaagag ctgaaaacaa
     3721 gtatcgtgtg ggaaaatagc aaatttaata gagaaaaaat tgtggaaaac tatgaagaaa
     3781 tatttttttc tcatttttat ctatcaatac taaagattcg ctcataatat cacaagtata
     3841 attgacattc tcaattaccg agagtattct atgtgagaat gattctcatt tatttgcgta
     3901 acacgtaaga aaattagaac atataatgaa tgattttaat acatgattta tttcacaaga
     3961 gaggaatcaa tatgcagacc ttagcgcagg caaagcagaa tttcgtttat caagtcgaac
     4021 gaatcgaaac agaagaaaaa acaaaacgcc atttgcaaaa tatcgggatc gttgccggaa
     4081 gtaaaatcgt cgtcgtcaat ttatcaggca acaatgccat tttactggta aaaagtcatc
     4141 gagtggcagt aagtcgggaa atactaggtc aaatctttgt caataaaaag actgcttcct
     4201 ctgaaagctg gacttctctt gatcaattaa aagcaggaga gactgggatc gtcgtagcaa
     4261 tccacggaca aggcgcagtg aagcgacggt taatggatat gggattgacg cgaaatgtaa
     4321 aaatagttat ccgaaaacta gcccctctgg gagatccaat cgaactgaca gtgcgagggt
     4381 atgaactgac gttacgaaag tcagaggccg aactaatctt gatacaaagg gaggaaaaag
     4441 aatgaatatc gcgttagtcg gaaatccaaa cagcgggaaa actagcttgt tcaatctctt
     4501 gactggttcg aatcaatatg tagggaattg gccgggcgta acagtagaaa aaaaagaagg
     4561 atcgttgaaa aaaaatccga acattcatat tcaggaccta cccggcatct attctttgtc
     4621 tccttataca ccagaagaag tgattgcaag agattatttg gttcaggaac agcctgaact
     4681 gatcatcaac attattgatg ctaccaattt agaacgaaat ctttatttaa ctacgcagtt
     4741 attggattta gacattccta tgatcattgg tctgaatatg atggatgtca tcaaaaaaga
     4801 aggaaaaaaa atcaatctag aaaagctttc ctatggtctt ggtgtaccag ttttaccaat
     4861 cagcgtattg aaaaagcaag gaatcgaaaa actaatcgaa aagattcagg agtctgcaaa
     4921 aaagcggcct tctattcctg ttccctgtac atatgatcca cgtttagaag cagctttaca
     4981 tgaaattgaa gatgtactag gagaacaaag cggcaagaaa cgctggtatg caatgaaata
     5041 ttttgaacga gatcagaagg taagagagga ttacgagata gcagtttctc agcaaaaaga
     5101 gatcgagcaa ctgatccagt taacagagaa actattggac gacgatagtg agacgattct
     5161 ggtcaatgaa cgttatgaat ttattaccca actatgtaca ctctgtgttg tgtcaaatga
     5221 ttctttccaa ttatcgatga gtgacaaaat cgatcagatt gcaacgaatc gttggttagc
     5281 cttgccgatc ttcgcatttg tgatgtggct gatctattat ctggctattc aaacagtagg
     5341 aacaatgggg acagattgga tcaatgacac attgtttggt acatggttac cagaacatgt
     5401 tggcagattg ttagctgaat ggcaagtagc gggatggatg caggagctga tcttgaacgg
     5461 catcatcgca ggcgtgggag cagtgttagg atttctaccg caattgatta tattgttttt
     5521 atgcttgagc tttctggaag actgcggata tatggcgagg atcgcttttg tcatggatcg
     5581 acttttcagg aaattcggtc tttcaggaaa atccttcatt cctatgctga ttgctacagg
     5641 atgtggagtg ccaggcgtca tggccagtcg cacgattgaa aacgagcaag atcgtcgttt
     5701 gacgatcatg gtcacaacct tcatgccttg ttctgcaaag ttgccgatta ttgccttagt
     5761 agcaggggcc ttttttcctc atcaatcttg ggtagctcct tctgcctatt ttcttggtat
     5821 gactgcaatt attttctctg gaatcagctt gaaaaaaaca cgtttgtttg ctggagatac
     5881 agctcctttt atcatggaat tgcccgcata tcattttcct caatggtcag cggtcctaag
     5941 acaaacctat gaccgcagca agtcttttgt taaaaaagca ggaacgatta tctttgtttc
     6001 tagtatcgtg atctggttca gctcttctta taatttttat gctcaacctg tttctgaaga
     6061 ccaaagtatc ttagcctttt tcgggcgaat cctggcagtt gtttttcagc cgcttggttg
     6121 gggaaactgg caaggaacag tcgcagcgat tacaggattg gtcgctaaag aaaatattat
     6181 tggcacattt ggtattttgt ttggtcatgc ggaagtatcc gaaaatggca gagaaatctg
     6241 gcaagtgcta caacacacat atactcccgc agcagcttat tcattgttag ccttcaattt
     6301 actttgtgcg ccttgttttg cggcaattgg ggctatccat cgggaaatga atgccaagaa
     6361 atggacttgg atcgccatag gctatcaatg cggtttagct tatttagtta gttttgtgat
     6421 ttatcagttg ggacacttat tggagggtgg acaggtagcg ttagggacgt atcttgctat
     6481 tttactgatg ataggactcg tttatgtttt gttccgtcag ccaaaatcca agaaccagtt
     6541 ttatactata ttgtcattag aaggagagga ataggatggc gacattctta ttaagtgtgt
     6601 taatctttgg aagtgcaggc gcaattgtct atactcgttt aaaatccggt aagaattgtg
     6661 atgactgtca aacagcttgc ccagtaaaaa aggaacagat caagcgatga tcagtcgttg
     6721 caagaggcta ttctcccctt ttttgcttat tttgctagag catagtaaga tgagggaaag
     6781 taaaaaaaga aagaggaaag aaaatgtctg gaaagaaaaa aatcgtccgc ccgcgctacc
     6841 agcagattgc tgttgattta gccgaacgta tcgttgaaaa ccgatataaa gtgggtgaga
     6901 agatccatgc ccgctcaaca cttgccagta cgtacaatgc ttctcctgag actacccgca
     6961 aggctatcaa tgtgctggta gatcttggaa tcatggaagt acggcatgga agtggggcat
     7021 ttgttgcttc gaaggaaaaa gcaaaagatt tcctattgca atatcaagat gtacaatcca
     7081 tccaagatac aaaagcagaa atcatggcaa gtgtggagaa gcaacaagat gagctgaatc
     7141 atttttctca attattggat cagctggtca atcaaacgaa gcgaatacat aagatgaatc
     7201 ctttacttcc gtttgaatta tctttatcag aaaaagcaat gcatctggac cgttcaatta
     7261 gcgagttgaa tatctggcag gcgactggcg ccacagttat cgcaatttct cataatgaag
     7321 aactgcttgt ttcacctggc ccctatgcta aatttacggc aggggacatc gttcatttta
     7381 ttggaaatga atatacacta cagcgtatga caaacttttt ttacccggag catcagcttg
     7441 cagaatgatt gtgtgaaata ttaaaaaaat attaacttgg ctaaaccttt tatttacaaa
     7501 gatttagcca agtttttttc agtttggaca agcaaatttc tttcattttt gacaaagtga
     7561 ctacatgatg ttaacatagt gtggtcactt ttttcagaaa gaaaaatgaa tttacataaa
     7621 aaaggagaat ttgtttggta aaagtagaag taaaacattt aacaaagata tttggtaaaa
     7681 agacacaagc cgctttagat atgatgaatg atcaccagcc gaaaacggag attttaaaga
     7741 aaaccggtgc aacggttggt gtgtatgacg tgaattttga cgtaaaagaa ggagaaatct
     7801 tcgtgatcat ggggctttcc gggagtggga aatccacatt gatccgtcta ttgaatcgtc
     7861 tgattgagcc aacttcgggc agtatctata ttgatggaga agatgtatcg aagttaagca
     7921 aagaagaatt gcgagaagtc cgtcgtcata aaatcaatat ggttttccaa aacttcggtc
     7981 tgtttccaca tcgaacgatc ttggaaaata cagaatacgg gttagaagtc cgtggtgtac
     8041 ctaaagaaga acgacaagaa aaagcagaaa aagcattaga aaattctagt ttgctttcat
     8101 ttaaagacca atatcctagt cagttatctg gtgggatgca acaacgggtt ggcctagcca
     8161 gagctttagc aaatgatcct gagatcttgc tgatggacga agcgttctcg gctcttgatc
     8221 cgctgatccg gcgagaaatg caagacgaat tactggacct gcaagccaat gttcaaaaaa
     8281 cgattatttt cattacccat gatttgaatg aagctttacg gattggggac agaatcgcct
     8341 tgatgaaaga cggcgaaatc atgcagatcg gaacaggtga agaaatattg accaatccag
     8401 caaatgatta tgtacgtgaa tttgtggaag aagtcgatcg ttccaaagtg cttacggctc
     8461 aaaacatcat ggtacctgca ttgacgacga atatcgaatc tgatggacca aacgttgcat
     8521 tgacaaggat gcgtaatgaa gaagtcagca tgctgatggc tgttgacaga aagagacacc
     8581 tgaaagggat catcactgca gatcaagcgt tagaagctag gaagcaaaaa cgtccattga
     8641 tcgacttcct agatgaaaat gtgacggtga ttgggaaaga catggtggta agtgatattt
     8701 tcaatattat ttatgactca ccgactccac ttgcagttgt agaggatgga aaattaaaag
     8761 gtgtcgtcat ccgaggtagt gtgattgaag cattagcaga aacaagcgag gtgagtgaac
     8821 atgaataatc tattgaacta tcaattacca gtggcaaact gggtagaaaa tatcacagaa
     8881 tggtttacga caactttttc tggcctattt tcatttttac aaacgattgg acaggcagtg
     8941 atgtcgggga ttacaaattt actgttagtg attccagctc ctttgtttat cttgttattg
     9001 acggtagcag ctttctttat ttctaagaaa cgtccaggac ttacgttgtt cacattaatc
     9061 ggtctatggt ttatttataa ccaaggtcta tggaatgatt tgatgaatac tgtcacactt
     9121 gttcttttat ctagtgtgat ctcgatcatc attggggtac cattagggat cttgatggca
     9181 aaaagcagta aagcccaaag tattatcaaa ccgatccttg actttatgca gacaatgcca
     9241 ggattcgttt atttgattcc agcagttgca tttttcggta tcgggatggt tccaggggta
     9301 tttgcctcag tcatctttgc tctgccacca accgttcgtt ttacgaattt agggattcga
     9361 caagttccta aagaattagt agaagcttct gattcattcg ggagcacaag tcgtcaaaaa
     9421 ctattcaaac tagaattgcc tttagctaaa agtacgatca tggcagggat caatcaaaca
     9481 acaatgctgt cactttcaat ggtcgttatt gcctctatga tcggtgcacc cggcttagga
     9541 cgcggcgtat tatcagcatt gcaaagagca caagtcggga atggatttgt caacggggtt
     9601 gcattagtta tcttagcaat catcattgac cgttttacac agcatttgaa ccagccaaac
     9661 aataaaaaag ctgcaggagc aacaacacag aaaagtaaaa aacgtcaagg actgatcatt
     9721 ggtgctgtag tagtagtgat cttaggtgcg attggtatag ggagtttttc atctgccaaa
     9781 gaaacaaaac gtatcaactt atcttatgtt gaatgggata cagaagttgc ttcaacaaat
     9841 gtagtcggtg aagtattgaa acaaatgggc tatgatgtaa cgatgacgcc attagataat
     9901 tcaatcatgt ggaaatctgt ttcaaatggc gagtcagatg ccatggtttc agcttggcta
     9961 cctaaaactc atggttcaca atatgcacaa tataaagatc aagtcgaaga cctaggtgcc
    10021 aatttgacag gagcaaaagt tggtttagca gtgccagcct acatggatgt aaattcgatc
    10081 gatgagttaa ccgatcaggc aggtaagaaa atcataggaa tcgagccagg agctggtgta
    10141 gttacggctg ctgaaaacac gatccaaaaa tatgacaact tgaaagactg gaaagtagag
    10201 acatcttctt caggagcaat gaccgttgca ctaggtcaag cgatcaaaaa acacgaacca
    10261 attgtagtta caggatggac acctcattgg atgtttgcca aatatgatct gaaatactta
    10321 gaagatcctg aaaacggaat gggaagcgaa gagcagatcc atacgatggt tcgaaaagga
    10381 ttgaaagaag accagccaga agcttacaaa gtattagaca atttccattg gtcagaaaaa
    10441 gatatggaaa aagttatgtt ggaaatcaac aatggaaaag atccacagca agcagcaaaa
    10501 gactggatca aagagaacca agaattagtc gaaagctgga aaaaataaaa agacagacac
    10561 gaaataaatg gagcttccaa aattggatca aatatccaaa tttggaagct ccatgttcgt
    10621 ctctatcttt tttgtctata aaaaaagaga atgcgtagct catcttcgaa acgttcaaag
    10681 acgccgacaa actattatga atttatgggt gcgagtcaaa gagatcgatc gtaggtatga
    10741 aagactaatg tgattaaagt ttattatgta cgaagtgcat tctcaaaaaa tattaaagaa
    10801 tatacatagt ttatatactt aaaagtgatt aaattcttat tcaggaatta ttttgctacg
    10861 tttcaagaag gaattgtttt ttgaaattta atgaatgtta gaataatagt ctaaaaacat
    10921 taatttaggg gtgattagat tatgaaacat ttaaaaattt tgtctattaa agagacacaa
    10981 cttatctatg ggggtaccac tcatagtgga aaatattatg gaaatggagt gtattgcact
    11041 aaaaataaat gtacggtcga ttgggccaag gcaactactt gtattgcagg aatgtctat
//
LOCUS       DAZKKZ010000081        10896 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.083, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000081 DAZKKZ010000000
VERSION     DAZKKZ010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10896)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10896)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10896
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.083"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            1..329
                     /locus_tag="ACG8LA_002489"
                     /pseudo
     CDS             1..329
                     /locus_tag="ACG8LA_002489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(327..1046)
                     /locus_tag="ACG8LA_002490"
                     /pseudo
     CDS             complement(327..1046)
                     /locus_tag="ACG8LA_002490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010745868.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
     gene            complement(997..1206)
                     /locus_tag="ACG8LA_002491"
     CDS             complement(997..1206)
                     /locus_tag="ACG8LA_002491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204765.1"
                     /translation="MDVLREYSSLFTEAYLLEQFGYKIPFADYQQGVGTAAELSFYEG
                     ISQAVGRPVDAEHFEQRISSTGKSE"
     gene            complement(1188..1256)
                     /locus_tag="ACG8LA_002492"
                     /pseudo
     CDS             complement(1188..1256)
                     /locus_tag="ACG8LA_002492"
                     /inference="COORDINATES: protein motif:HMM:NF024811.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
     gene            1483..2756
                     /locus_tag="ACG8LA_002493"
                     /pseudo
     CDS             1483..2756
                     /locus_tag="ACG8LA_002493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250512.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(2863..3894)
                     /locus_tag="ACG8LA_002494"
     CDS             complement(2863..3894)
                     /locus_tag="ACG8LA_002494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0204766.1"
                     /translation="MFLEIHDLNLFFDEKQILAIDEIQIEKGELVTLLGPSGCGKSTL
                     LRCITGLEQPKSGEIVLDNENIADKPTKDRNIGFVFQQYALFPTMTVFENVAFGLKVK
                     KLSPEVIQEKVFEMLSLVDMTEQADKNVQFLSGGQRQRVALARSLVTEPKVLLLDEPL
                     SALDARIRKQLQRDLRAIQQSLGMTMIFVTHDQEEAMRISDRIFVMEAGRVAQVSTSK
                     ELYQNPQSRFVAEFIGNYNRFEWYELNQYTHEFSAKGNRCIYYLRPELIQFEPVPQGV
                     KIPVLWKESFILGNIQRYVFQTLEGKEILVDRLNDREEKISDALYIQLKDILAIPVEI
                     DTQHFAQQS"
     gene            complement(3901..4731)
                     /locus_tag="ACG8LA_002495"
     CDS             complement(3901..4731)
                     /locus_tag="ACG8LA_002495"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFQ0204767.1"
                     /translation="MKKLIKPILFCFVLYYLLPIIGTILYASSTKWSKSLLPSDFTLQ
                     WFQQLLTDREFIAAVGRSLLLAGVVLVTILLLMIPTIIWIHLYFPRLNRWLEKLLLLP
                     YALPGVILVTALLRTYAETGIPMFVVLVGALFITALPIVYLSLNNQMRLINLKELVDA
                     AETLGAPMSTIIIQVLFPNIRIGVTLVSLMIFSSVFGEYMLTNLLIGGRFQTVRIYML
                     RRMNENGHLASAVMVLYLLFMVGIALTTFMLTYRQKQQLSLKQTREEKQSKKKPLKEL
                     "
     gene            complement(4728..5543)
                     /locus_tag="ACG8LA_002496"
     CDS             complement(4728..5543)
                     /locus_tag="ACG8LA_002496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFQ0204768.1"
                     /translation="MKEMKKRLVLVPASFIFCAFLLLPLLFMVLCSLHSDLTNQWTLA
                     NYSDIFSNKYYTQAFVNSVLIAVSSSVIGLIGTFILCLCLMNLSTKLQEKITFVSNLA
                     ANFAGIPLAFSFIILLGNVGVLKMILPFLADFNLYSWWGLTITYTYFQIPLGVLFLYP
                     SMKEVKKEWLESAQLLGASSAYAWFKVALPFLRPSIASTFVILFANGMGTYETAYALT
                     SSNVNLLTIRIAALVSGDVFAKPNLGSALAVALGVLLVTAMLIIQKKGKVVQT"
     gene            complement(5540..6364)
                     /locus_tag="ACG8LA_002497"
     CDS             complement(5540..6364)
                     /locus_tag="ACG8LA_002497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline phosphatase family protein"
                     /protein_id="HFQ0204769.1"
                     /translation="MQSRLDKLIVVILDGCRYDTAVAQLGFMNHLVEHQQASLLKVKS
                     ELPSNSRPLYEVLMTGVPAYENGIYSNYHAQRSKEWSLFELVKEAGGKTGAAAYHWYS
                     ELYNQAPYNRLVDRIQHQEERLIQHGIFYSEDTYPDSHLFADAHYLVNQYQPDFLVVH
                     SMNIDDVGHKFTADSHEYAAAVNQADRLLAIYLPEWLQKGYQVVVTADHGMDAHGLHG
                     GSLAAHREVPFYLISNKRQKLKEQTVPQLLAAPLFCWLLGIAPSEKMQDIQELMRG"
     gene            complement(6354..7454)
                     /locus_tag="ACG8LA_002498"
     CDS             complement(6354..7454)
                     /locus_tag="ACG8LA_002498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HFQ0204770.1"
                     /translation="MKMNEKIRNMTIGLFCAATVSILLTGCGSGEATKQSAAADDSLD
                     TIIEKAKEEGEIASLGMPDTWANWVGTWNDLEKEYGLSHVDTDMSSAEELAKFESEGK
                     NGTADIGDVGISFGPLAESKELTLPYKTNYWEEIPDWAKDDDGDWLLSYTGTISFITD
                     KENVKQAPTSWKELQEGDYQVSVGDVTIANQAQFAVLAAAIANGGDEKDIQPGLNYYK
                     KMAEKGRLSTVDASVANLEKGEIDVAVVWDFNGLNYRDQIDSERFEVTVPTDGSIISG
                     YTTLINKNAPHPNAAKLAREYILSDEGQINLAKGYARPIRKVELPKEVAEKLLPEDAY
                     EAAVPVEDNEAWNKTSVELPELWQAEVLTYAK"
     gene            7632..8417
                     /locus_tag="ACG8LA_002499"
     CDS             7632..8417
                     /locus_tag="ACG8LA_002499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HFQ0204771.1"
                     /translation="MQYYDQHLHTYFSFDSEEKFENYLAYQPEFFVSTDHFDLNNPST
                     GKDDIPDYPAYINKLDSLKETYSTKFLRGIEIGVVPGQEERIVDYLAQHPYDLKLVSI
                     HQNGRFDYMDDVVLTKDPIQTTKEYFDQMLQVLTDFPEGDILTHFDYGLRRFTFTAEE
                     FAEHFEAQLLTIFKKVVERELAMELNAKSFLKYGNEDLYRYAVPLYQSVGGKLFTLGS
                     DAHVAEDYQLGFKKMSQLLADCQVEKLLVIQGKERRLTPLPIL"
     gene            8450..8833
                     /locus_tag="ACG8LA_002500"
     CDS             8450..8833
                     /locus_tag="ACG8LA_002500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HFQ0204772.1"
                     /translation="MSNLWDYNQEAPIHYLIARHWDALKIEAVCRSLLAAVPKQQLEN
                     FLVADSLQREKVQAYFAAFKDQPLEYLHAQFHLFYQVAAPDDYNDLRGQLQLTFQADE
                     TAYTVLLGMARLGDQAKVEWRIFDI"
     gene            8909..9040
                     /locus_tag="ACG8LA_002501"
     CDS             8909..9040
                     /locus_tag="ACG8LA_002501"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: protein motif:HMM:NF012387.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFQ0204773.1"
                     /translation="MLVTDAGEIRLRLFPDQAPLAVANWRSLAEQGVYDNTPFGSCH"
     gene            9009..9245
                     /locus_tag="ACG8LA_002502"
     CDS             9009..9245
                     /locus_tag="ACG8LA_002502"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFQ0204774.1"
                     /translation="MTTHLSARVIKEFVIQGGALDGSGDEAVSSYEGFFADEVHRGLY
                     HFNGALALGDHGPHTNGNQFFIVQNTKAQADLLM"
     gene            9257..9343
                     /locus_tag="ACG8LA_002503"
                     /pseudo
     CDS             9257..9343
                     /locus_tag="ACG8LA_002503"
                     /inference="COORDINATES: protein motif:HMM:NF012387.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
     gene            complement(9323..10294)
                     /locus_tag="ACG8LA_002504"
     CDS             complement(9323..10294)
                     /locus_tag="ACG8LA_002504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HFQ0204775.1"
                     /translation="MEGTVLRIEQGSLHDGAGLRTVVYLKGCPLRCAWCSIPESQSKQ
                     IEKGFGQTMTAEEVMDEIEKDAVFYFHSDGGVTISGGEALVQADFAKEILQKSKYIGI
                     NTVLETSFCGAYNEIQKVAPYVDTLFVDVKMFTSKLHKQWTGLDNQQILKNIRRFLIE
                     YPNCEVRIRVPVVPGINMNLTELLTIACFVADLDRFVPLELLPYHCYGMHGYQALGLE
                     YPLADTPAPSPKEMFALADQLARTVPHLLVTALTKTFIYLLNPSFILWINERHSLAAA
                     SSRIELLLKSVSVFLRCFFEVNLSNEHWLNRYIFTVCRLSCDRCYDF"
BASE COUNT         3244 a         2530 c         2080 g         3042 t
ORIGIN      
        1 actcagatgt tgaaagtcaa agaaaagttg actattttag aattaaaacg tacccgtttt
       61 ctatgctatg attgtgggca gaccttttct gcgaaaacgg acttagttga tgaacatcat
      121 caactaacaa aggaactgaa acaggcgatt ctcatagaac tgtacgaaaa tcaatcacgt
      181 aatctgaaaa tcagaagaag taccgtcggc tcaagcgata ttggaaactc ttactcaaag
      241 attccacgac attggagccg ctcaaacggc attatcatcg actgtttaaa cgaccaatta
      301 gtcaaacaga aatcgtcgat gaaccgttgt gcacaatggt gtcctgaacg tacagcgaca
      361 ccttccatat ccagagcagt cgccacatca cggggatgga tgccatccaa attaaaagca
      421 accacgccag tatgatgttc aggatcttgc ggtccgtaaa tggtgatacc gccgatcgct
      481 tgtaatttag gtaaaacgta ggcaaccagt tcttgctcat aacgatgaat attctccata
      541 ccaatctcat tcaagtaatc gattgctcct gcaatgttcg gagtaccagc ttcaaatttc
      601 catggcagct ctttccatga actatcgtaa agattgacaa aatctatcat ttcaccgccg
      661 aattcgactg gctccatttg ttctaacaat tgacgtttgc catataatac accgattcct
      721 gtcggcccgc acattttatg cccgctaaag gcgaaaaaat ctgcatccaa cgcttgtaca
      781 tcaactgtca tatgcggtgc tgcttgggca ccgactggac tatcctcaac tacaacagcc
      841 tgttcaaccc tcagccgttt caagcacaac aaataacctt ctggatctgg tttgccgacc
      901 tgaagatcat cgatcgtcac aaaggaatca attttttcct taatcatcgg atgtgcttca
      961 aaaaaatagt ctagctcccg cagttcagaa ttgagactac tccgattttc cagtgctgct
     1021 gatccgctgc tcaaaatgtt cagcatccac tggtctccca accgcttgac ttatcccttc
     1081 ataaaaggac agttctgctg ccgtcccaac accttgttga tagtctgcaa aaggaatttt
     1141 atagccgaac tgctccagta aataggcttc agtaaatagt gatgaatact ctcgtaaaac
     1201 atccattcac tgtcaatcat cgtcccatca aaatcaaaaa taagtgcttt ggtcatcttc
     1261 tttccccctt acccaaaaca agcaaaagct gtgtcctgct ctctctacag tatcagcata
     1321 aaaactgccg tctgaaaagt caaaggtgaa agaaatgtgg cgctataatt tctaggactg
     1381 atagtaaatc attctatcag tccttttgag cataaaaaaa caaaacatac agaagctccg
     1441 ttagaattga atcaccacaa cacaatcaaa ggagcgttct gtatgcctga tcttcatctt
     1501 atcaaactat tactaggaat caaagatgga aacattcaaa tcactcatgt cgagaagaaa
     1561 aaaatacatt caatcaacag tatcgttgtt tctgccacgc tcattaaaac gattcagccc
     1621 tgtcctcagt gtaaacaggt gaatcaacat gggctgatcg ttaagaacgg aaagaaaaaa
     1681 tcgctggtcc ttctcaataa gtgtgcgaat caacggactt atcttgcttt ggcaaagcaa
     1741 cggtacctct gtcgtggctg tcacacctat tttacggcga atacctacat tgttgaaaaa
     1801 aactgtttta tcgccaaaca agtacattat aaaatattgg aggaattgac tgaaaaacaa
     1861 gcaatgacga cgatttctaa acattgcggc gtttcttggt caaccgtttc gcgaacactc
     1921 gcttctctgc tccccatgac aaacgtgaaa ataaattggt tgcctcgctg ttcattggta
     1981 gatgaatttc gttcattgaa aaatcaagtc ggtccctatt ctttttcttg tatggatggc
     2041 gatactggga aattactgga tattcttcct tcacgtaaga agaaagatct catttcttat
     2101 tttatgcaat ttgaacgacg tgcacgttta aacgtaaaaa tactcgtaac agatatgaac
     2161 gcctcttatg ctttgctgat aaaagagtgc tttcctcatg ccaaactcgt tgtggatcgc
     2221 tttcacatcg tcaagcacct cattcgcagt tttaaggata tttgactatg agtcatgaaa
     2281 agcttcgacc gaaacgatcc aatacaagcc aaacactatc gacaagtgaa ggctttatct
     2341 cgacttctga tcaaacgaca ggacacgctt gtttatgata aatggacaaa atggcgtaat
     2401 tttggttggg cctatttaac cgaaagtgaa gtcgtagaac gtctactttc tacttctgat
     2461 gaactacgaa tagcttatgc ttactatcaa gaaattcttc aagcttttta tgacaaagaa
     2521 gcggacatct tctttcagct tgtaaaaaca atgcccaagt cggttccaag agaactgcat
     2581 catataaaaa aagcgtttat aaactatgaa tccggcattc gtttagcctt agagttgcct
     2641 tactcaaatg gcaaaataga aaatctgcat acccacatca aagcattgaa acgaatagct
     2701 tacgggttag gatgagaacc agaattttct taatcaatca tctgatcact tattaaacat
     2761 aaaaaaacat ctaaagcaga aaatcaattc taccttagat gttcttatat cactctatca
     2821 gtcctatttg acaaagagcc agaaatgttt gccgactata cactagcttt gttgtgcaaa
     2881 atgctgagta tcaatttcca cagggattgc tagaatatct ttcagctgaa tgtataaggc
     2941 atcgctaatt ttctcttccc gatcgttcaa ccgatccact aaaatttctt tgccctccag
     3001 cgtttgaaaa acataccgtt gaatgttgcc taaaataaat gattccttcc atagaaccgg
     3061 aatcttaacc ccctgaggaa ccggttcaaa ttgaatcagc tccggtctta aataataaat
     3121 gcagcgattg cccttagcgg aaaactcgtg ggtatactga ttcagctcat accattcgaa
     3181 acgattatag ttgccgataa attccgcaac aaatcggctc tgaggattct gatacaattc
     3241 cttcgaggtg gaaacctgag ccacccgccc agcttccatc acaaaaatcc gatcactgat
     3301 tcgcatcgcc tcttcttggt catgagtcac aaaaatcatc gtcatcccta gcgattgctg
     3361 gatagcgcgc aaatcccgct gcagctgttt tctaattcgg gcatccaaag cacttaatgg
     3421 ctcatccagc agcaggactt tcggttcagt gaccaatgag cgagccagtg ccacccgttg
     3481 tcgttgaccg ccagaaagaa actggacatt tttatctgcc tgctccgtca tatccaccaa
     3541 tgatagcatc tcaaaaacct tttcctgaat cacctcagga ctcagcttct ttaccttcaa
     3601 accaaaggct acattttcaa aaacagtcat agttggaaac aatgcatact gttgaaaaac
     3661 aaagccgata ttgcgatcct tcgtaggctt atcggcaata ttctcattgt ccagcacaat
     3721 ctcaccgctc tttggttgtt ccaatcccgt gatacagcgc agcaacgtag actttccgca
     3781 cccgctggga cctagtaaag taaccagctc acccttttca atctgaattt catcaatagc
     3841 taaaatctgt ttttcatcaa aaaacagatt gagatcatgt atttctaaaa acattttccg
     3901 tcacaactcc tttaagggct tctttttcga ctgcttctct tccctcgtct gcttaaggga
     3961 cagctgttgc ttttgtcgat aagtcagcat aaaggtagtt aaagcaattc ccaccataaa
     4021 cagcaaatac aaaaccatca cagcgctagc caaatggccg ttttcgttca tccgccgcag
     4081 catatagatg cgtaccgtct gaaatcgacc gccaatcaac aggttcgtca gcatgtactc
     4141 cccaaaaacc gaagaaaaaa tcatcagaga aactagggtc acaccgatac ggatgtttgg
     4201 aaacagcacc tggataataa tcgtagacat cggggcgccc aaggtttctg ctgcatccac
     4261 taattccttc agattaatta agcgcatctg gttgttaaga ctaagataga caatcggcaa
     4321 cgccgtaata aacaatgcac ctaccaacac tacaaacatt gggataccag tttcagcata
     4381 cgttcgaagc aaagccgtta ccaaaatcac tcctggtaaa gcatacggca gcaggagcag
     4441 cttttccagc caacgattca aacgagggaa atacaaatga atccaaataa tggtgggaat
     4501 catcaacaac agaatcgtca ccaagaccac acctgctaat aaaagtgagc gacccaccgc
     4561 agcaataaat tccctgtccg tcagcagctg ttggaaccat tgcaaggtaa aatcactagg
     4621 taaaagcgat tttgaccatt tagtggagct ggcatacaaa atcgttccaa taatcggcag
     4681 caagtaatac aggacaaagc agaacaaaat cggttttatt aactttttca cgtctgcacc
     4741 accttgcctt tcttttgaat aatcaacatt gccgttacca gcaggacacc taaagcgact
     4801 gccaacgcac tgcctaaatt aggcttggcg aacacatctc ccgacactaa agccgcaatt
     4861 cgaatcgtta aaagatttac attactgctg gtcagggcat acgctgtttc ataggtcccc
     4921 atgccattag caaataagat gacaaaggtg ctggcaatcg atggtcgcaa aaaaggcaaa
     4981 gccaccttga accaagcata cgctgatgaa gcgcccagca attgtgcgga ctccagccat
     5041 tcctttttca cttccttcat gctgggatac aaaaacaaga cccctaacgg aatttggaaa
     5101 taggtatacg tgatggtcaa tccccaccaa gaatacaaat tgaagtccgc tagaaatggc
     5161 aaaatcattt tcagcacacc tacattcccc aacaaaataa taaaagagaa tgccagcgga
     5221 atcccagcaa aattagctgc caaattggaa acaaaggtga ttttctcctg caatttagtc
     5281 gatagattca ttaagcataa acataaaata aacgtcccga ttaacccaat cacactggag
     5341 ctgacagcaa tcagtacgct gttaacaaag gcctgtgtgt aatatttgtt gctgaaaata
     5401 tcactgtaat tggccaatgt ccactggtta gttaaatcac tgtgcaagct gcacagaacc
     5461 ataaaaagca gcggcagcag taaaaatgca cagaagataa aggaggcagg aaccagaacc
     5521 aagcgttttt tcatctcttt catcccctca tcaattcttg aatgtcctgc attttctctg
     5581 acggtgcaat tcctaataac cagcaaaaca atggagccgc cagcagctgt ggtacagttt
     5641 gttccttcag cttttggcgt ttatttgaaa tcaaataaaa aggaacttca cgatgtgcag
     5701 ccaagctgcc gccatgcagt ccgtgcgcat ccatcccgtg atccgcagtc accacgactt
     5761 gataaccttt ttgcagccat tcaggaaggt aaatagccaa taatctgtcc gcctgattaa
     5821 ccgctgctgc atattcatga gaatcggcgg taaatttgtg accgacatca tcaatattca
     5881 tcgaatgtac gaccaaaaag tctggctgat actgattcac taaataatgg gcatccgcaa
     5941 ataaatgcga atcagggtaa gtgtcctcac tataaaagat gccatgctga atcagtcgct
     6001 cctcctgatg ctggatgcga tcaaccaaac gattataggg ggcttgattg tacaactcgc
     6061 tgtaccagtg gtaagcggcg gctcctgttt ttccgccagc ttccttaact aattcaaaca
     6121 gcgaccactc tttggatcgc tgagcatggt aattactata gatgccattt tcataggctg
     6181 gaacgccggt catcagtact tcgtataacg gacgtgaatt gctgggcagc tcacttttta
     6241 ccttcaataa gcttgcttgc tggtgctcaa ctaaatgatt catgaaccca agctgggcga
     6301 cggctgtgtc gtagcgacag ccgtctagta taactacaat cagtttgtca agtctacttt
     6361 gcataggtca gtacctccgc ctgccaaagc tctggaagct ctacagaggt cttgttccaa
     6421 gcttcattgt cttcaactgg caccgccgct tcataagcat cctccggcag taatttttca
     6481 gctacttctt taggcagctc taccttgcga ataggtcgcg catagccctt tgccaaattg
     6541 atttgccctt catcagataa aatatattcc cgtgctagct ttgccgcatt gggatgaggg
     6601 gcatttttat tgattaaggt tgtatacccg ctaatgatgg agccgtctgt tggcacagtt
     6661 acctcaaaac gctcggagtc aatttggtca cgataattta gtccattgaa gtcccaaaca
     6721 actgccacat cgatttcacc tttttcaaga tttgctacgc tggcatcaac ggtggacaaa
     6781 cggccttttt ctgccatttt tttgtagtaa ttcagacctg gctgaatatc cttttcgtca
     6841 cctccgttgg caatcgccgc agccaataca gcaaattgtg cttggttggc aatcgtcaca
     6901 tcccccacgc taacttgata gtcaccctct tgcagctcct tccagctagt cggtgcttgc
     6961 ttcacattct ctttatcggt gataaaggaa atggttcccg tatagcttaa caaccaatcc
     7021 ccatcatcat cctttgccca atccggaatt tcctcccaat agttggtctt ataaggtaag
     7081 gttaactctt tgctttcagc caacggaccg aagctgatac cgacatcacc aatatcggcg
     7141 gttccatttt ttccttctga ttcaaactta gccaattctt ctgcactgga catatccgta
     7201 tccacgtgac ttaagccgta ttctttttca aggtcgttcc aagtgcctac ccaatttgcc
     7261 caagtatccg gcattcccaa gctggcaatc tctccttctt ccttggcttt ttctataatc
     7321 gtatctaaag agtcgtctgc cgcagccgat tgcttcgttg cttcacctga gccgcagcct
     7381 gtcagcagga tacttactgt tgctgcacaa aataaaccga tagtcatgtt acgaattttt
     7441 tcattcattt tcattcattc ttctcccctt tcgataattc cattctaaca aagctttgta
     7501 atgagagaat cagtttcttg aaaaggtttc atgaacaatg taaaggttgt atatggtttg
     7561 taaatttcga cgaattcccg ttaaccttct aaagcttttg cggtatgata gtagaaaaaa
     7621 ggaggctccc tatgcagtat tatgatcagc atctccacac gtatttttcc tttgattcag
     7681 aggaaaaatt tgaaaactat ttagcctatc agccggagtt tttcgtttct acggatcact
     7741 ttgatttaaa caatccatct accggaaaag atgacattcc ggattatcca gcctatataa
     7801 acaaactgga ctctttaaaa gaaacctatt ccaccaaatt tctgcgaggt atcgagattg
     7861 gcgttgttcc aggacaagaa gagcggatcg tggattacct cgctcagcat ccttatgatt
     7921 taaagctggt aagtattcat caaaatggcc gctttgatta tatggacgat gtggttttaa
     7981 ccaaagatcc cattcaaact accaaggaat attttgatca gatgttgcag gtcttgacgg
     8041 attttccaga aggagatatt ttgactcact ttgattatgg attacgccgc ttcaccttca
     8101 cagcggaaga attcgcggag cattttgagg ctcagctgct aacgattttc aaaaaggttg
     8161 ttgaacgaga attggcgatg gagttaaatg ccaagagctt cttgaaatac ggcaacgaag
     8221 acctttaccg ttatgccgtt cctttgtatc aaagtgtcgg cggaaagctc tttaccttag
     8281 gctcggatgc tcatgttgcc gaagattatc agctgggctt taaaaaaatg agtcagctgt
     8341 tggcagactg tcaggtagaa aagttgctag tcattcaagg aaaagaacgc cgcctgacgc
     8401 cgctgccgat tttgtgattc ctatataata gaagaaagtg gtgaaaaaaa tgagcaacct
     8461 gtgggactac aatcaagagg cacccatcca ttatttaatt gcgcgacatt gggatgcgtt
     8521 gaaaattgag gcggtttgcc gatccttgtt agcagccgtt ccaaaacaac aactggaaaa
     8581 ttttttggtg gctgacagct tgcagcggga aaaagttcag gcttattttg cagcctttaa
     8641 agatcagcct ttggaatatt tgcatgcgca gtttcatctt ttttatcaag tagccgcccc
     8701 agatgactac aacgatttac gaggacagct gcaattgacc tttcaagcgg atgaaaccgc
     8761 ctataccgtt ttattgggaa tggctcgcct tggtgatcag gcgaaggtcg agtggcggat
     8821 tttcgatatt tgatggcagg atcaaggcgt ttcagttgca aaccttcctc tctttcaatt
     8881 agaaaaaccg cagcaggaag aagtttgtgt gctggtcacc gatgctggtg aaattcgtct
     8941 ccgcttattt cctgaccaag ctcccctggc tgtagccaac tggcgctccc tagctgagca
     9001 aggcgtttat gacaacacac ctttcggctc gtgtcattaa ggaatttgtt attcaaggtg
     9061 gcgctttgga tggttctggt gatgaagctg tttccagcta tgagggcttt ttcgctgatg
     9121 aagtgcatcg cggactttat cattttaatg gcgccttggc cttaggggac cacggccccc
     9181 acaccaacgg caaccagttt tttattgtgc aaaacacaaa ggcgcaggct gacctgctaa
     9241 tgtaaagcaa gcatacttgg agcttggagg actaccggag ctggatggtc gttatactgt
     9301 ttttggacag gtataccaag ggttagaaat cgtagcagcg atcgcagctc agccgacaaa
     9361 cagtgaagat gtaccgattg agccagtgtt cattcgacaa attaacttcg aaaaaacatc
     9421 gtaaaaagac actcactgac ttcagcaaaa gctctattct tgagctggct gcagctagtg
     9481 agtgtctttc atttatccat aagataaagc ttggattcaa taaataaata aatgttttgg
     9541 ttaaagctgt gaccagcaaa tgaggaaccg tgcgagccag ttgatctgcc aatgcaaaca
     9601 tttctttagg tgaaggcgct ggcgtgtctg ccaacggata ctccagtccc aatgcttggt
     9661 aaccgtgcat accatagcag tggtacggta gtaattctaa cggtacgaac cgatcaagat
     9721 ctgccacaaa acaagcaatc gtcagcagct cggtcaggtt catattgata cctggaacca
     9781 caggaactcg aattcgcact tcgcagttag gatactcaat taaaaagcga cgaatattct
     9841 tcaaaatttg ttggttatct aagccggtcc attgtttgtg gagcttgctg gtaaacattt
     9901 ttacatccac aaacaatgta tccacatagg gagctacctt ttggatttca ttataagcac
     9961 cacaaaagct ggtttccagt acggtattga ttccaatgta tttcgatttt tgcaaaattt
    10021 ctttagcaaa atccgcctga accagtgcct cgcctccgct aatggtcact ccgccatccg
    10081 agtgaaagta aaaaacagca tccttctcaa tctcatccat tacctcttca gcggtcatgg
    10141 tctggccaaa tcctttttca atctgcttgc tttgtgattc gggaatcgaa caccaggcac
    10201 agcgtaatgg gcagcccttt aaataaacaa cggtccgtaa accagcacca tcatgtagag
    10261 aaccctgttc tattcttaat actgttcctt ccatatagat ttttgaatta cacactagtt
    10321 taaactaaaa cacacaagga aaaacttacc atttaatcat aaaattagct catataaata
    10381 tactaggatg taaaatagac tggtcaaaat ctggtcaaaa aagaggacta atacaggtag
    10441 tcctcttttt tgttatttta atattctaaa tcatttttta ttggtttatt cccttattcg
    10501 atgtagactc aaatcactat atcactagat atcaaacggc gtcatacgga atcaaaaaca
    10561 tcaaatttga cctgttaaat ggtcattgaa taacattcaa aatcaataaa acggagtcag
    10621 acacggagtc aaaaacgctg agagtaaaaa atatatacag ccttgtaggt aaagtaccac
    10681 agggctgtat attttttatt tcagattacc ttaaatgatt ccatttactt tttatctcat
    10741 tttttcctac tagttagtat caaatactct cctattttct caataaacta tttttggata
    10801 catggtatct gaaacagcta aaaccttgtc attacagcaa aaaatcacgt tatccagact
    10861 gtagacaaag tccattttat ggatgatgtc tacagt
//
LOCUS       DAZKKZ010000082        10173 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.084, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000082 DAZKKZ010000000
VERSION     DAZKKZ010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10173)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10173)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10173
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.084"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(47..871)
                     /gene="iolB"
                     /locus_tag="ACG8LA_002505"
     CDS             complement(47..871)
                     /gene="iolB"
                     /locus_tag="ACG8LA_002505"
                     /EC_number="5.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016861 - intramolecular oxidoreductase
                     activity, interconverting aldoses and ketoses [Evidence
                     IEA];
                     GO_process: GO:0019310 - inositol catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-deoxy-glucuronate isomerase"
                     /protein_id="HFQ0204776.1"
                     /translation="MEKTLKHQPLNKELAPGVKQIQNIRQSNSALSYIEFQILELEKG
                     ASYKETGSQQEVCIVILTGKIKVKAADTWYEDLGTRESVFEKIPTDSIYLPAEHSFEL
                     VATTDNVRLALCYSPAKKALPISVIRAEDNTVEERGLYQNKRLVHNILPDNVDTASSL
                     LVVEVYTEGGNFSSYPPHKHDQENLPHESFLEETYYHELDPEQGFVFQRVYTEDRSLD
                     ETMTVEHQNVVEVPKGYHPVGVPDGYTSYYLNVMAGPERIWKFHNEKKHEWILQRK"
     gene            complement(910..2826)
                     /gene="iolD"
                     /locus_tag="ACG8LA_002506"
     CDS             complement(910..2826)
                     /gene="iolD"
                     /locus_tag="ACG8LA_002506"
                     /EC_number="3.7.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002397168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016823 - hydrolase activity, acting on
                     acid carbon-carbon bonds, in ketonic substances [Evidence
                     IEA];
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA];
                     GO_process: GO:0019310 - inositol catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3D-(3,5/4)-trihydroxycyclohexane-1,2-dione
                     acylhydrolase (decyclizing)"
                     /protein_id="HFQ0204777.1"
                     /translation="MEKTVCLTTAQALLKFLNQQYISIDGKETPYVEGIFHVYGHGNV
                     LGIGQALELEPGHLKSYSGKNEQGMAHAATAFARQNLRKKIFAVSTSVGPGAANLLTA
                     AGTAFANNIPVLFLPADTFATRQPDPVLQQLEHASSVAFSTNDAFQAVSRYWDRINRP
                     EQLMSALLRAFEVMTNPATMGPATICLPQDVEAEAYAYPEEFFKKRVHYIDRRIPTAR
                     ELAEASQRIKASKRPVIIVGGGCKYSEAGEILEQISRDCQIPLVETHAGKSTVSWDFK
                     NNLGGMGILGTSAANKAVQQADLIIGIGTRYTDFTSASKSIFNFEQAKMMNINVSRQQ
                     AAKLEAFQVVGDAKATLEQLAPMIEGYQTAYGEKIDELKEEWISERNRLKAAHFKRKD
                     FTPEIKDHFSQEILNEYADALATNLTQTEVFIHLNDFVDEDAIVIGSAGSLPGDMQRL
                     WNPVKENTYHLEYGYSCMGYEIAGAMGVRMARPEQEVYALVGDGSFLMLHSELVSSLQ
                     YDKKINIVLFDNSGFGCINNLQMDNGGASQGTEFRNTKDEIMNIDYAKVAEGYGAKTY
                     RVSSIAELQAAVEDAKKQTRSTLIEIKVLPKTMTEGYDGSWWNVGISEVSGKAAMQEA
                     YKAKQAKLATIRKY"
     gene            complement(2837..3871)
                     /gene="iolC"
                     /locus_tag="ACG8LA_002507"
     CDS             complement(2837..3871)
                     /gene="iolC"
                     /locus_tag="ACG8LA_002507"
                     /EC_number="2.7.1.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016618711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047590 - 5-dehydro-2-deoxygluconokinase
                     activity [Evidence IEA];
                     GO_process: GO:0019310 - inositol catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-dehydro-2-deoxygluconokinase"
                     /protein_id="HFQ0204778.1"
                     /translation="MSYIKFDQSKEFDLLLLGRVAIDFNPAYNDQVKEEFKPLKKVHM
                     FEKFVGGSPANIAVGVTKHGMKAGFIGTVSDDQFGEYVIDYFNEQGIDTSQISKAQHG
                     EKLGLTFTEMLSSKESNILMYRNQAADLQLSVEDIDEDYLKRSKALLISGTALAESPS
                     REAVIKAVMLAKRNNVKIIFDIDYRAYNWKNNDDISIYYSMIAKESDIIMGSREEFDL
                     TEKLIQPNMSDNESAAFWHSCGAEIVVIKHGMKGSTAYTADQQQFSIKPFPVEARKGF
                     GGGDGYGSGFLYGLFEGWEIIDCLEFGSAEASMMVKSNNCSDSLPTTQEVKDFITLEK
                     EIYGEMIARI"
     gene            complement(4028..5044)
                     /locus_tag="ACG8LA_002508"
     CDS             complement(4028..5044)
                     /locus_tag="ACG8LA_002508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016633586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFQ0204779.1"
                     /translation="MAGTIKEIAEKAGVSRGTVDRALNDRGRINPEVAERIRAIAKEM
                     NYVPKKKKVIKETTLKLGIVTQLAKSSFMIPIRSGLESIIGDLKKRNIDCFLEEVDGV
                     DEAAQLQALDRLVELGVKGIAIMPVDSDGIREKINQLTDQGILIITFNSDILGTNRQC
                     FVGMDNFKSGKTAAGLLGMLTKGKGKVLAITGYFGNSVNSLRVAGFVEELKESFPELE
                     LTGVQSSFDSSAEVEKILSNTLENYSNLDGVVVFSGGQAGIARALEKIDESKRPFVII
                     YDLTKNNIEMLKNDQVDFLIDQDGFVQGYRSLLMLANQLQNNKTVTKDALFTDIIIKT
                     KYNI"
     gene            complement(5146..5298)
                     /locus_tag="ACG8LA_002509"
     CDS             complement(5146..5298)
                     /locus_tag="ACG8LA_002509"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204780.1"
                     /translation="MDVVKFLDDADIANDPNNPPQFTCEKCGKEMYPEYYRNALGIEF
                     KISDVQ"
     gene            complement(5315..6634)
                     /locus_tag="ACG8LA_002510"
     CDS             complement(5315..6634)
                     /locus_tag="ACG8LA_002510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016372324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS91 family transposase"
                     /protein_id="HFQ0204781.1"
                     /translation="MKANILEAIFFDEHHNWDNFVEKYGRKIRLVVKREVNKFRYCGD
                     IQKGYRLFVCEGCHQTKFVPLKCRGKFCPTCATGESQRWSAVVANDMFKVTHRHVIFT
                     IDEGLREIFMMENYRDSLLKGLMDEAAKIILAYFEKRKVKAGIVATIHTFGSKLEFNP
                     HVHMVVTMGGLTRDGSWEEYDYLPFSMLRKYWKNAVLKLIRRTLGEWDKQRVQSRLQA
                     AYKNNGEGFYVNAPKRSRTNLKSLLQYISRYMKRGPIALSRILMYDGDTVMFNYMDKR
                     TNTKETMTMSIDEFIAALIRHIQNKNFKTIRRYGIYSRRIKTLMKKVMKEYQKRVKKL
                     FINLNEALRPKSWEERITEEFGENPLECSCCGEYYEFVGMSVRKNGRLVIKYAKDNHA
                     KRFMREENRKIDQKEFRQQYEEEKEKTFKAIRWDWERQREIYMSKLW"
     gene            complement(7012..7104)
                     /locus_tag="ACG8LA_002511"
     CDS             complement(7012..7104)
                     /locus_tag="ACG8LA_002511"
                     /inference="COORDINATES: protein motif:HMM:NF013677.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFQ0204782.1"
                     /translation="MPRRSFDEIFKITAVKLVTEEGFSVKEVSL"
     gene            complement(7375..8355)
                     /locus_tag="ACG8LA_002512"
     CDS             complement(7375..8355)
                     /locus_tag="ACG8LA_002512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HFQ0204783.1"
                     /translation="MLFLKKEDIIKSFSMREAIDADKKALSLYSAGKASVPLRTNIDV
                     PKSNGQSLYMPAYVEGGEGALGVKIVSVYPENIKKNLPSVPATMIVLDPETGMVSACL
                     DGTYLTQLRTGAVQGAATELLAREDAKIGALIGTGGQAQSQLEAMLTVRKLEEVRIFD
                     IDFERASQFAEKMMQQFSVTMRPTKTSQECVEGADIITSVTTSKRATFSAEWVKKGAH
                     INGVGAYTPEMCEIPREIIKAADVVIFDTMDGVLKEAGDFISPLQDGYIQRDSYHGEL
                     GQLINEELIGRTSGEQITIFKTVGSAVLDVVVATEIVKKAKENNLGKLIF"
     gene            complement(8368..9246)
                     /locus_tag="ACG8LA_002513"
     CDS             complement(8368..9246)
                     /locus_tag="ACG8LA_002513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TSUP family transporter"
                     /protein_id="HFQ0204784.1"
                     /translation="MIRNILLTLIVAINLYFIIYFLRDLFKNKQNFKEEPGDMRLLPF
                     TSFIIFFLSTFGVSDFAIGTVLYPKLKWVSMKKLPGTLNTQCVVPVAVMALSYITAIN
                     VGIKTLAVCIICQIIGAYLGPRFVVKLPEKTIKLFVGIGLVIAALLIFAGQMNWIPSN
                     GTASELYGGKLILAGFLLFVYGALNNIGIGSYALTMVTVYLLGLNPVAAFPIMMGACT
                     FSVPIGSVQFIKFNEYSRKITLFTSTFGVLGVLVAVFLVKSLDTYILKWIVILVLLYS
                     AYTMLGSQLKKVTAAN"
     gene            complement(9262..10062)
                     /locus_tag="ACG8LA_002514"
     CDS             complement(9262..10062)
                     /locus_tag="ACG8LA_002514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrmB family transcriptional regulator"
                     /protein_id="HFQ0204785.1"
                     /translation="METIIQIMKKYDFSEMETRVYTTLLEKGNLTGYEVSKISGVPRS
                     KVYNILEKLLKKNLIVVNKSEPKLYHAISANEFLEKLEKSVKNDLSFLTKNLGMIKEK
                     DEEEMLWKVDGIEYVLDKVEHLVKNAKESLLIQVWHENFTDSLLKALQQAEKRVDKFV
                     LILFSSTHEYDLPLEKYYIHGFETDKLADFGARWINIVADEQEVVFGTINEELQSTDV
                     TWTKNHAMVNLAKEYVKHDAYTLKVIAESPEELKAKYGEGFEGIRKIY"
BASE COUNT         2752 a         2356 c         1720 g         3345 t
ORIGIN      
        1 acctaactaa acctaactaa actttatgta tctaacagct taataactac ttgcgctgca
       61 agatccattc gtgtttcttt tcattgtgga atttccaaat tcgctcaggt cccgccatca
      121 catttaaata gtaggaagta tacccgtcag gtaccccaac tggatgatag cccttaggaa
      181 cttcgacgac attttgatgc tctaccgtca tcgtttcatc tagtgaacga tcttccgtgt
      241 agacccgctg gaaaacaaat ccctgctctg gatcaagctc atggtaataa gtttcctcta
      301 aaaaagactc atgtggcaga ttctcttgat cgtgcttatg aggaggatag ctggaaaaat
      361 taccgccctc ggtataaact tcgacgacca gcaggctgct ggcagtatcg acattatccg
      421 gtaaaatgtt gtgaacaagt cgtttattct gatagagtcc acgttcttcg acggtattat
      481 cctccgcgcg aatcacactt atcggcaaag cttttttcgc tggtgaatag caaagcgcca
      541 atcggacatt gtctgtagtt gccacaagtt caaacgaatg ctccgccgga agataaatac
      601 tgtcggttgg aattttttca aaaacagatt ctcgtgttcc taaatcttca taccaagtgt
      661 ctgctgcttt aaccttaatt tttccagtca aaatgacgat acagacctcc tgttgactgc
      721 cggtttcctt gtaagaagct cccttttcca gctccaaaat ctgaaattcg atataactca
      781 aagcagaatt agactgccga atattttgga tttgttttac tccaggtgcc agttctttgt
      841 ttaatggttg atgcttcaat gtcttttcca atcaatccac tccttatttt caatcacaaa
      901 aagcaatatt taatactttc tgatagtggc aagtttcgct tgtttggctt tgtaagcctc
      961 ctgcatggct gctttacccg atacctctga gataccgacg ttccaccagc tgccgtcgta
     1021 gccttctgtc atggttttag gaagtacctt tatctcaatc aacgtcgatc gcgtttgctt
     1081 cttcgcatcc tcgaccgctg cttgtaattc tgcaatcgag cttacacgat acgtttttgc
     1141 accatagcct tcagcaactt tggcgtaatc gatgttcatg atctcgtcct tggtatttct
     1201 gaattcggtt ccttggctag ctccgccatt atccatctgt aaattattga tacagccgaa
     1261 accagaatta tcgaaaagta caatgttgat ttttttatca tattgcaaac tagaaaccag
     1321 ctcgctatgc aacatcaaga aactgccatc gcctactaag gcatagacct cttgttctgg
     1381 tcgagccatt cttacgccca tcgcaccagc gatttcatag cccatacaag aataaccgta
     1441 ttccaaatga taggtattct ccttcacagg gttccataag cgctgcatat cccccggcaa
     1501 tgaaccggct gaaccgatca cgatcgcatc ctcatcaaca aaatcattta aatgaatgaa
     1561 gacctctgtt tgcgtcaaat tcgtagccaa cgcatcagca tattcattca agatttcttg
     1621 agaaaaatga tctttgattt ctggcgtaaa atctttacgc ttaaaatgcg cggcttttaa
     1681 ccgatttcgc tcactgatcc attcttcctt cagttcatcg atcttctcgc cataggcggt
     1741 ttggtaacct tcgatcattg gggcaagctg ctccaaggtc gctttcgcat caccaaccac
     1801 ttgaaaggct tccagcttag cggcctgttg tctgcttacg ttaatattca tcattttcgc
     1861 ttgttcaaaa ttaaaaatac ttttagaagc tgaggtaaaa tcagtgtagc gtgtgccgat
     1921 ccctatgatc agatccgctt gctgcacagc tttattagca gccgaagttc ccaaaatccc
     1981 cattccgccg agattgtttt taaaatccca cgaaacagtc gatttacctg cgtgcgtttc
     2041 aactagcgga atctgacaat ctcttgagat ttgctcaaga atctcaccag cctccgaata
     2101 tttgcagccg cctcctacga tgatgacagg tcgtttactg gcctttattc gttgactcgc
     2161 ttcagcaagc tcacgagcgg tcggaatcct gcgatcaata taatgtactc tttttttgaa
     2221 aaattcctcc ggataggcat aggcttctgc ctccacgtcc tgcggcaaac aaatcgttgc
     2281 cggacccatc gttgccgggt tcgtcatgac ttcaaaggcc cgcaataacg cggacatcaa
     2341 ctgctctggt cgattgatgc ggtcccagta gcgagaaacc gcttgaaatg catcatttgt
     2401 cgaaaaggct acactgcttg catgttccag ctgctgcaag accggatcag gctgacgtgt
     2461 agcaaacgta tccgccggta aaaaaagtac ggggatatta tttgcgaatg ccgtacccgc
     2521 tgctgttaac agattggccg cgcccggtcc aacagatgtt gatacggcaa aaattttctt
     2581 gcgtaaattc tgtctggcaa aggcagtagc cgcatgggcc attccctgct cattttttcc
     2641 gctataactt ttcaaatgtc cgggctctaa ttccagcgcc tgaccgatcc ccaaaacatt
     2701 tccgtgacca tagacatgaa agataccttc aacataaggc gtttctttgc cgtcgatgct
     2761 gatgtattgt tgattcaaaa attttagtaa tgcttgtgct gttgttaaac aaaccgtctt
     2821 ttccattttt ttcaccttaa atccgagcga tcatttcgcc gtatatttct ttctccaatg
     2881 taataaaatc ttttacctcc tgagtcgtcg gtaaagaatc tgaacagtta ttgcttttga
     2941 ccatcattga tgcttccgct gagccaaact ctaaacaatc gatgatctcc cagccttcga
     3001 ataaaccgta taagaaaccc gagccgtaac catctccgcc gccaaagcct ttgcgtgctt
     3061 ccaccggaaa cggcttgatt gaaaactgct gctgatcggc cgtataagca gtcgatcctt
     3121 tcattccatg tttgattacg acaatctcag caccacaact gtgccaaaaa gcagcgcttt
     3181 cattatctga catgttaggc tggatcaact tctcagttag atcgaactct tctcttgaac
     3241 ccatgataat gtctgattcc ttagcaatca tcgaatagta aattgaaata tcatcgttgt
     3301 tcttccagtt ataagcacgg taatcaatat caaaaataat tttgacatta ttccttttcg
     3361 ccagcatcac tgccttgatt acggcttctc tggacgggct ctctgctagt gcagttcctg
     3421 agattaatag tgcttttgac cgtttcaagt agtcctcatc aatatcctca acgctaagct
     3481 gcaggtctgc ggcttgattt cgatacatca aaatattact ttcctttgat gagagcattt
     3541 cggtaaaagt cagccccagc ttttcaccat gctgcgcttt gctgatctga gacgtatcga
     3601 tgccttgttc attgaaataa tcgatcacat attcgccaaa ctgatcgtcc gagactgttc
     3661 cgataaaacc agctttcatg ccatgtttag taacacccac agcaatattg gcaggagatc
     3721 cgcccacaaa tttttcaaac atatggacct ttttcaatgg tttaaactct tctttgactt
     3781 gatcattgta ggcaggatta aaatcaatag cgactcttcc taaaagcagc aagtcaaatt
     3841 cttttgattg gtcaaacttt atataactca atatatccac ctctttatcc gttcttctat
     3901 ttctgaggca agtatagcac gccaaaacaa agcgtgcaat atttatttta gaacgcaata
     3961 ttgcgtgctg tttgaaaatg acggcaaaaa aaacgtgaat cgccttacat cacgattcac
     4021 gcctagatta aatattgtat tttgtcttaa taattatatc agtaaatagc gcatcttttg
     4081 taaccgtttt attattttgc agctgattcg ctaacatcag taatgaacga tagccttgaa
     4141 caaatccatc ttgatcgatt agaaaatcaa cctgatcgtt tttcagcatc tcgatattgt
     4201 tcttagtcaa atcataaatg attacaaagg gccgcttgct ttcatcgatt ttttccaacg
     4261 ctcgggcaat tcccgcttgt ccgccagaaa agacgactac gccatctaag tttgaataat
     4321 tctccaaggt gttgcttaaa atcttttcaa cctcagcact cgaatcaaag ctgctctgaa
     4381 cacccgtcag ctccagttca ggaaacgact ctttcaattc ttcaacaaag cctgccaccc
     4441 gtaagctgtt gacgctattt ccaaagtagc cggtaatcgc tagaaccttg ccctttcctt
     4501 ttgtcagcat acctaacaat cccgcagccg tttttccgct tttgaagttg tccatcccaa
     4561 caaaacactg tcgattcgta ccaagaatat ccgaattaaa ggtaatgatg aggatgcctt
     4621 gatcggtcaa ttgattaatt ttttctctga taccatcact atctactggc atgatcgcga
     4681 tcccttttac tccaagctcc accaatcgat ccaacgcctg cagctgggcc gcttcatcga
     4741 ccccgtctac ctcttctaaa aaacaatcaa tgtttcgctt ttttaaatcc ccgataatag
     4801 attccagacc tgatcggatc ggaatcataa aagaagattt cgccaattga gtgacaatcc
     4861 ccagcttgag cgttgtctct tttatgacct tctttttctt tggaacatag ttcatttcct
     4921 tggcgattgc tctgattctt tctgcaacct caggattgat ccttcctcga tcgttcaatg
     4981 cccgatccac tgtccccctt gacactcctg ctttctcagc tatttcttta attgtacccg
     5041 ccatcttgcc tctccttttt tcctattgtg tttattttat cacaaaactt aagaaaacca
     5101 ccggagaatg aattctccgg tggacttttt gtatgattaa ccttcttatt gaacatcact
     5161 gatcttaaac tctattccaa gggcgtttct ataatattct ggatacatct ccttcccaca
     5221 tttttcacag gtaaattggg gaggattgtt cggatcattt gcaatatctg catcatctaa
     5281 aaattttact acatccattg ggattgattc tttttcacca caacttagac atataaattt
     5341 cacgttggcg ttcccaatcc cagcgaattg ctttaaaagt tttttctttt tcttcttcat
     5401 actgttgcct gaattctttt tggtcaattt ttcgattctc ctctcgcata aaccgctttg
     5461 catggttatc tttcgcatat ttaataacta accgtccatt tttgcgcaca ctcatcccaa
     5521 cgaattcata gtactcaccg caacaagaac attctaaggg attttcacca aattcttcgg
     5581 ttattctttc ttcccaggat tttggtctta aggcctcatt cagattgata aacagctttt
     5641 ttactcgttt ctgatactcc ttcatgacct ttttcattaa tgttttgatt ctacgactat
     5701 agattccata gcgacgaatc gttttgaaat tcttattttg aatatggcga atcagtgcag
     5761 ctatgaattc gtctatactc atggtcatcg tctctttagt attcgttcgt ttgtccatgt
     5821 agttgaacat gacagtgtcg ccatcataca ttaagattcg gcttaatgcg atcgggccac
     5881 gcttcatata acgactgatg tattggagta gtgactttag atttgtcctg ctccttttag
     5941 gagcatttac gtaaaaccct tctccattgt tcttgtacgc agcttgtaat cttgattgaa
     6001 ctctttgctt gtcccactca cctaacgttc gtctaattag tttcaataca gcatttttcc
     6061 agtattttct taacatagaa aaaggtaaat aatcgtattc ttcccaactt ccatctcttg
     6121 ttaagccacc catagtaaca accatatgaa catgcggatt aaattctagt tttgatccaa
     6181 aggtgtggat tgtagctact atacctgcct tcacctttct tttctcaaaa taggcaagaa
     6241 taatttttgc ggcttcatcc attagtcctt tcagtaagga atctcgatag ttttccatca
     6301 taaagatttc ccgtaacccc tcatcgatcg taaagattac gtgccgatgt gtcactttaa
     6361 acatatcatt cgccacaacc gctgaccacc tttggctttc acctgttgca cacgttggac
     6421 agaactttcc acgacatttc aagggaacaa actttgtttg atgacatccc tcgcagacaa
     6481 acagtcggta tcctttttga atatctccac aatatctaaa cttgtttact tcccgtttga
     6541 cgactagccg aatctttcgc ccgtatttct caacaaagtt atcccaatta tggtgttcgt
     6601 caaaaaagat tgcttcgaga atattcgctt tcatagtaat attttacttg ttcaaaaaca
     6661 aaatgaaaag ggctaaaaga ctggtagtgc agccttttta gcccttaact ttttatactt
     6721 tctttactgt ctaaaaaata tgcggcgcac agaacgcgcc gcatatcgga ctaagtttta
     6781 ttcaaatttg tcttcgccaa cacaatttga cgaagagcct tttctttcag gaagacttcg
     6841 gtaattttta ggagttctac ctattctttt aaccgtttat tctctttttc taagcgtgta
     6901 atttcatttc tgcgaatgga tttcatgact tcctctaccg agaaaagtac gttatccata
     6961 tttttcaact tcttgaactc atcaatacac gctattagag cgagcttcta gctatagact
     7021 aacttcttta acagaaaacc cttcttccgt taccagtttt acagcggtaa ttttaaatat
     7081 ttcatcaaat gaacgtcttg gcataatcca gatcttcgct ttctcttaat ttggtgtcaa
     7141 ttttagtata acccgtccaa cttatttttt aactaagtgc ccggtttttc ttgacaactc
     7201 cacccaaaag ttagattttt tggtctaagt tttagggtcg cttcattact agaattcaac
     7261 aagagatgtt ttttatttta tttaaattat ggggtcagtt tccatttgat tacaaacttc
     7321 tttgttttct ttttttaaac gcaataataa aggttttaat ttcagccttt ttaattagaa
     7381 aatcaatttt cccaaattat tttctttagc tttcttaacg atttctgtcg caactaccac
     7441 atctaataca gccgaaccaa ctgttttgaa gatcgtgatt tgttctccac ttgtccgacc
     7501 gatcaattct tcattgatca gttggcctag ttccccatga tagctgtctc tttgaatata
     7561 cccatcttgc agcggtgaaa tgaagtcccc agcttctttt agaacaccgt ccatggtatc
     7621 aaaaataaca acatctgcgg ctttgattat ttctcgtgga atttcacaca tttccggtgt
     7681 gtaagcaccg actccattga tgtgcgcacc ttttttgacc cactcagcag agaatgtcgc
     7741 acgttttgaa gtggtcacac ttgtaatgat gtctgctcct tcaacgcatt cttgactggt
     7801 ttttgttggg cgcatcgtta cagaaaattg ttgcatcatt ttttcagcaa attggctggc
     7861 acgctcaaaa tcaatatcaa aaatccgaac ttcttctaat ttacgaacgg tcaacattgc
     7921 ttctaattgt gactgtgctt gtccgccggt tccaatcagc gcgccaattt tagcatcttc
     7981 tcttgcaaga agttctgttg ctgctccttg aacagcgcct gttcttaatt gtgtcaaata
     8041 agtaccatcc aaacaagcgg ataccatacc cgtttctgga tccaatacga tcatcgttgc
     8101 tggtacactt ggtaagtttt tcttgatgtt ttcaggatac acggaaacga ttttgacacc
     8161 tagcgcgcct tcgccacctt ctacataagc aggcatatat aagctttgtc cgttgctttt
     8221 tggcacatcg atattggtgc gaagaggcac acttgccttt cctgctgaat acaatgacag
     8281 tgcttttttg tccgcatcga tggcttctct cattgaaaaa cttttgataa tatcttcttt
     8341 tttaagaaat aacatttgaa tcgctcctta attagctgct gtaacttttt ttaattgact
     8401 gcccaacatc gtatatgcac tgtatagtaa gaccaaaatc acgatccatt tcaggatata
     8461 ggtatctaaa gatttgacta ggaatacagc gaccaatacc cccaatacac cgaaggttga
     8521 agtaaaaagt gtgatttttc tgctgtattc attaaattta atgaattgaa cactgccgat
     8581 cggtactgag aaggtacaag cccccatcat aataggaaag gctgcaactg gattcaagcc
     8641 tagcaagtag acagttacca tcgttaacgc ataagaacca atgccgatat tgttcaatgc
     8701 accatagaca aagagtaaaa atcctgccaa gattaatttt ccgccataca attcactggc
     8761 tgttccgttt gatggaatcc agttcatttg tcctgcaaaa atcaacaatg cagcaatgac
     8821 caatcctatg ccgacaaaca gtttgatcgt tttctctggt aacttcacga caaatcttgg
     8881 tcctaaatat gcaccgataa tttggcagat aatacaaaca gctagtgtct tgatccctac
     8941 gttgatggca gtgatgtaag acaatgccat gacggctacc ggtactacac attgggtatt
     9001 caacgttccg ggtagttttt tcatgctgac ccatttcaac tttggataaa ggacggttcc
     9061 gatagcaaag tcggaaacgc caaatgttga aagaaagaag atgataaatg acgtgaaggg
     9121 caacagacgc atatcccctg gttcttcttt gaaattttgt ttgtttttga aaaggtctct
     9181 tagaaagtaa ataataaaat atagattgat tgcgacaatt agtgtcagca aaatattccg
     9241 aatcataaaa aattcctcct actagtaaat ctttctgatt ccctcaaagc cctcaccata
     9301 ttttgcttta agttcttcag gagattctgc aatcactttt agtgtatatg catcatgttt
     9361 gacatattct tttgctagat tgaccatggc gtggtttttt gtccaagtga catcggttga
     9421 ttgcagttct tcgttaatgg taccaaacac gacttcttgc tcatcggcga cgatgttgat
     9481 ccatcttgct ccaaagtcag caagtttgtc tgtttcaaaa ccatgaatat aatacttttc
     9541 taagggaaga tcatattcat gggtagaact gaataaaatc agtacaaact tatcaactct
     9601 tttttcagct tgctgcaatg cctttagtag tgaatccgtg aaattctcat gccaaacttg
     9661 aatgagcaaa ctttcttttg cgtttttcac caaatgctct actttatcca gaacatactc
     9721 gataccatca actttccaca gcatttcttc ttcatctttt tctttgatca tccctagatt
     9781 cttggtaaga aaagaaagat catttttaac acttttttct aatttctcta aaaactcatt
     9841 tgccgagatg gcatgataaa gtttaggttc tgatttatta acgacaatca aattcttttt
     9901 taatagtttt tccaaaatat tatatacttt cgagcgtggc acacctgaga ttttacttac
     9961 ttcatatcct gtaagattac ctttttctaa tagtgtggta tacactcttg tctccatctc
    10021 tgaaaaatca tattttttca tgatttgaat aatcgtttcc attgattaat cctcacttta
    10081 tttttagtag ctactacggt aacaactata aattcttttt gattatctgt caagagttag
    10141 ttcaataaca cacatataat aattagctta aaa
//
LOCUS       DAZKKZ010000083         9976 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.085, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000083 DAZKKZ010000000
VERSION     DAZKKZ010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9976)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9976)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9976
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.085"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(440..664)
                     /locus_tag="ACG8LA_002515"
     CDS             complement(440..664)
                     /locus_tag="ACG8LA_002515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204786.1"
                     /translation="MKSDKYKNRKHTSWKTFREIIGSYLAVVVFLPLLYMAMTEQTRF
                     IGVDTQYIAETGFLFIFILIFAFYKSFHTK"
     gene            855..3632
                     /locus_tag="ACG8LA_002516"
     CDS             855..3632
                     /locus_tag="ACG8LA_002516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFQ0204787.1"
                     /translation="MNKLLKKEILCYLENQTAFFDLEHMNEVFTAQRLADHFGVKRNT
                     VSHYLNQLNDEQLLVKINSRPVIYFHKEAFEKQFFKLRTNFYFSIDDLKEEQPFFAQP
                     KDLFSFMIGYDASLKESIEQIKTALYYPDGGLPLLITGESGTGKSYLVNLVYQYCLLH
                     DLLEDSAPFITFNCAQYADNPELLTSNLFGHVKGAYTGAEENKKGAFEAADGGILFLD
                     EVHRLTPEGQEKLFTYLDQGVIYRMGEPNLSRRIKTRLFFATTEEITSHFLTTFIRRI
                     PIRIELPALNQRSRNERLELIYSFFLEEQRKMGSPLSVSGPALSLLTSQKLSGNIGEL
                     KNIVKVSAAKAYAEQREQPEIHVTIHHLQKELLAQPITKNTAQQGIYITQDQTLEQLM
                     EKQQPEQQRIVKSFEQILIDFKKNNCLLYSCEGKLKQEVIQLFDFLLFETSRQEKHEL
                     LVYWTQSIRETFRQMETAYQIKFDGNSVYALSYYLYQRSTIKWLPEEHDIIQLIKELE
                     QQVSQSYPSSYHYVQRILELSKIKLDIEDTSMDRILLTIYLKKAKWSKEKRLPKAMIA
                     AHGYATASSMANVVNRLLQEDLFESFDMPLDVTPQQIASEILDYCENSDVSNGLIILV
                     DMGSLKEIHQFFKKQLSVPLLILNNVTTPLAITVGECLQKNVSLEEIAEETVRQIQPE
                     WRLLYPEENKPKALITTCFTGIGTAVHLSELLEKSLPTACQLKIIPYEYQQLKDKKNS
                     DPLFSIYEVVGMIGTTDPDITNIDYLSLEDLISGEKMSVLAEWLDTTMNASEKEIFNQ
                     RIIRNFSLEKVLDSVTILDTEKVMGEIDHFMRELEVQLNRSISNPKKLALYVHVSCLI
                     ERLIRQMPIETYQGLEKWKQCQKEGLSAIKSAFSVIEEHYSVMIPNSEIAYIYDILSE
                     DTEFLSIEEEF"
     gene            3713..4132
                     /locus_tag="ACG8LA_002517"
     CDS             3713..4132
                     /locus_tag="ACG8LA_002517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFQ0204788.1"
                     /translation="MDREIILASHGKFASGILDSLELIYGKNHSITVFDCYTDENFDL
                     AETVRQLFMRYKDKEIIVLTDLFGGSVNNEFLQYINRDHVYLVAGLNLPLLIELVSRL
                     DAEVETTVLIQQVLTDSKKMIQFCNERLNQKIEEDEF"
     gene            4144..4614
                     /locus_tag="ACG8LA_002518"
     CDS             4144..4614
                     /locus_tag="ACG8LA_002518"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFQ0204789.1"
                     /translation="MIVLTRVDHRLLHGQVAFSWTQTIGADCILIANDDVPTNEIRKT
                     TIKLAKPQGVKLVIKSIDDSIAALKSGVTDKYKLFIVVESIEDAYKLAEAYPEIKTIN
                     LGGIKAKPGTRSIGKAVNILPEEEERLKRLIDKQIEVEIRQVPADKKVDVREVL"
     gene            4631..5410
                     /locus_tag="ACG8LA_002519"
     CDS             4631..5410
                     /locus_tag="ACG8LA_002519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HFQ0204790.1"
                     /translation="MIVQAVLLGIVAFVAQSEYALGTSLLSRPIVTGLFTGIVLGDVK
                     TGIIMGATLELAFIGSFSVGASIPPDVVTGGILGTAFAITAGAGTETALLLGLPIATL
                     TLILKNIYLGLLIPIMNHKADNYAEEGNYKGVEHMHLLAGIGLSLMLGVVVMVSYMVG
                     SNTIGNLLNMIPDFVQKGLSVATGLIPALGFAMLARLLINKQVAPYFFLGFAIASYLE
                     IPVTGVAIFGAILAVVVVNIMNVRQLPLQTTAGEVEEDEEF"
     gene            5397..6218
                     /locus_tag="ACG8LA_002520"
     CDS             5397..6218
                     /locus_tag="ACG8LA_002520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HFQ0204791.1"
                     /translation="MKNSEIKNSKITKKELNHVFWRSFQMEFSWNYERQMNMAYVYAM
                     IPILKKLYQSKEEMAAALKRHLEFFNTTPHIVTLILGITAAMEEENKDDPEFDVTAID
                     SIKTSLMGPLAGLGDSFFWGTLRLIATGVGTSLAMQGNILGPILFILIFNIPHILFRY
                     LATGWGYRLGTGFLKKIQANGMMESLTLGASIIGLMVVGAMTATMITINIPLKIGSGE
                     NAVTVQSIFDDIVPNILCLGAFGIVFYLLKKEVKPLTILIGLAFFGIFGSWIGIF"
     gene            6235..7284
                     /locus_tag="ACG8LA_002521"
     CDS             6235..7284
                     /locus_tag="ACG8LA_002521"
                     /EC_number="3.5.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HFQ0204792.1"
                     /translation="MFTMQDYIYEEKEVLSTILKKNDFSTREHMKKTVNLLILATGSS
                     YNACLAAKPALESYGDLTVDIQEPFYFFNYGKLSPSIDTVIAVSQSGKSASTVEAVKM
                     IQKQGLPVVAITNDVQSPLALEAAQIIDLGAGVESVGFVTKGYSATVLQLLLLGIGIG
                     ISKNKISKKIEQDYMQQLRKIINHLPAIIQKTEEFFDGYQSLFRLAQRFVTIGYGPNW
                     GTAKEAETKLTETIRVPSQGFELEAYMHGPYLEADASHLLFFIEGESVNKERSQKLQR
                     YMSRYVGETLTITTKKARNEKTLGLAIECDEYLSVLALVVPFQLFAYKTAVAKGIDLN
                     KKIFEDFDTVLKSKL"
     gene            7297..8301
                     /locus_tag="ACG8LA_002522"
     CDS             7297..8301
                     /locus_tag="ACG8LA_002522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HFQ0204793.1"
                     /translation="MLKFNEEEQIKAIKGALALRPQVEEIIDKLYAEKFDAVYYLGIG
                     GTYASSMQAVTYMNGKSNLPVFVQHAAEYYTTGNKRLTKDSIVILSSVTGTTQEVVKA
                     VEQIKKVGATLIGFIDKANSKLSQLCDFVVTYPAPGTEQIKFFMAADRLMYLNGEFEA
                     YSEYYEQLERYLPTGLVEAEKKADAFGLSFAEKHRRDSMHYFIGAGNQWGAVYSYAMC
                     YWEEQSWLPSKSIHAAEFLHGTLEIVEETTPVTLFLGEDEQRVLSERVAKLLPKICSN
                     YTLIDTKDYPVEGISEKYRGRVLSFLLMHVVTQRIDAHVEQLNCHPLEIRRYYRQFDY
                     "
     gene            8934..9953
                     /locus_tag="ACG8LA_002523"
     CDS             8934..9953
                     /locus_tag="ACG8LA_002523"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009331 - glycerol-3-phosphate
                     dehydrogenase (FAD) complex [Evidence IEA];
                     GO_function: GO:0047952 - glycerol-3-phosphate
                     dehydrogenase [NAD(P)+] activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0046168 - glycerol-3-phosphate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HFQ0204794.1"
                     /translation="MKQKIAVLGPGSWGTALAQTLAENGHDVRIWGNVPEQIDEINKY
                     HTNQHFLPDLTIPESIIGYKELAEAVDNADAILFVVPTKAIRSVAQELIGKMNTKPII
                     IHASKGLEQDTHKRISEVLAEEIPEEKRQAIVVLSGPSHAEEVAVHDITTITAASIDQ
                     KAAAYVQKLFMNDYFRIYTNNDVIGVETGAALKNIIAIGAGAIHGLGFGDDAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLIVTCTSVHSRNWRAGNLLGQGHKLEEVLE
                     NMGMVVEGVATTKAAVELAQQLGVEMPITQTIYNVLYNGEDIKKAAKEIMLRDGKMEN
                     EFSLR"
BASE COUNT         3349 a         1646 c         2089 g         2892 t
ORIGIN      
        1 gtgggttgag agaaatctaa ttgattttca aagaaggagt atgaaaatga gaaaaatatt
       61 tattcgttta ttgtgggtac tatcttagag gaataaataa tagtggagaa aactatggtt
      121 tggcgcagat tctatcaggt ttgatggaac gaagacaacc tcccgacatc aagtcaaaag
      181 ctacttgaga ttttgatctg aaaataaaaa aagaaaacaa ggtaggaaca tcaatgtttc
      241 taccttgttt tcgtaatcaa tgggaaaaaa ctaagagtgg tgtacgtaat caataaaaag
      301 gatggtgaca acagtacctc tttactctct gaaagcatca taactcgttt ttcctcatta
      361 tgccaataaa ttgttgttat accacatata aggatttgta atagctaaaa acagacagga
      421 aagttgaaat ctgtgaatct tattttgtat ggaaggattt atagaacgca aaaatcaaga
      481 taaagatgaa taaaaatcct gtttcggcta tatattgcgt atctacgcca ataaaacgag
      541 tttgttctgt catagccata taaagcaaag gcaaaaatac aactacagcg agataagatc
      601 cgatgatttc tcgaaaagtt ttccaggaag tatgtttcct gtttttatat ttatccgatt
      661 tcattgaata gtcatagcct ccttattctt tcatatgttg aaattccagt ataaaaactg
      721 gaaggaactg tacgtttttt agaataaaaa ttataaggga taagtaggct gctgtctata
      781 ataagatata tttttcaatt ctttattaaa gattttattg acaaaatgaa tccgttttct
      841 atgatggagg aggggtgaat aagttgttga agaaggaaat tttatgttac ttagagaacc
      901 agacagcctt tttcgattta gaacatatga acgaggtctt tacagcacaa aggttagctg
      961 atcattttgg ggtaaaaaga aacacagtca gtcattattt gaaccagtta aatgatgagc
     1021 aactactagt caaaatcaat tctcgaccag tgatttattt ccacaaagaa gcttttgaaa
     1081 aacaattttt taagttacgc acgaattttt atttttctat cgatgatctc aaagaggaac
     1141 agcctttttt cgcgcaacca aaagacttat tctcttttat gatcggatac gacgccagtt
     1201 tgaaagaaag tatcgaacaa atcaaaacag ctctttacta tccagatggc ggattaccac
     1261 ttttgattac aggcgaaagt ggcacaggta aaagttattt agttaatttg gtctatcagt
     1321 attgtctgct tcatgatctg ctagaagatt ctgcaccatt catcactttt aattgtgcac
     1381 aatatgcaga taatcctgaa cttttgacta gcaatttgtt tggacatgtt aagggagcgt
     1441 acactggtgc agaagaaaat aaaaaagggg cttttgaagc agcagatggt gggatcttgt
     1501 ttttagacga ggtacatcgc ttaacaccag aaggtcagga aaaactgttc acctatcttg
     1561 atcaaggtgt gatttatcgt atgggagaac ctaatttgtc acgccggatc aaaacacgtc
     1621 tcttttttgc tacgactgaa gagattacta gtcatttctt aacaactttc attcgaagaa
     1681 tacctatccg aatcgaacta cctgcactta atcagcgtag tcgtaatgaa cggctagaac
     1741 tgatttactc tttttttctc gaagaacaaa gaaaaatggg gagccctttg tcagtcagtg
     1801 gaccagcttt gtcactttta acaagtcaga aattatccgg aaacatagga gagctgaaaa
     1861 atatcgtcaa agtttcagca gcaaaagcat atgctgaaca gcgtgaacag cctgaaatcc
     1921 atgtcacgat ccatcatttg caaaaagaac tacttgcgca gcctattact aaaaatacag
     1981 cacagcaagg aatctatatt acgcaagacc agaccttaga gcaattaatg gagaagcaac
     2041 agcccgaaca gcagcgaatc gttaaaagtt ttgagcaaat cctaattgat ttcaagaaaa
     2101 ataactgtct gctatattct tgcgaaggaa aattaaagca agaagtgatt caattatttg
     2161 attttttgct gtttgagacc agtagacaag aaaaacacga gctgctggtt tattggacac
     2221 aatctatccg agagaccttt cgacaaatgg aaactgccta tcaaatcaaa ttcgatggaa
     2281 acagtgtcta tgccttgagt tactatctct atcagcgaag cactatcaaa tggttaccgg
     2341 aagaacatga tattatccaa ctaatcaaag aattagaaca acaagtttct cagtcttatc
     2401 catctagtta tcactatgtc caacgaattc tggaattaag taagatcaaa ttagatattg
     2461 aagacacaag tatggatcgg attttactga cgatctatct aaaaaaagcg aaatggtcaa
     2521 aagaaaaacg actgccaaaa gcgatgattg ctgctcacgg ttatgcaact gctagcagta
     2581 tggcaaatgt agtaaatcgt ttattacaag aggatctatt tgaatcattt gatatgccac
     2641 tagatgtcac accacagcag attgcttcag aaatccttga ttattgcgaa aacagcgatg
     2701 tttcaaatgg attgatcata ttagtagaca tgggatctct gaaagaaatc catcagtttt
     2761 ttaaaaaaca gttatccgta ccgcttttga ttttgaataa tgtgacgaca cctttagcaa
     2821 tcacagtagg ggaatgcctg caaaaaaatg tatcattaga agagatagca gaagagactg
     2881 ttcgacagat ccagccagaa tggcgactgc tctatccaga ggaaaacaaa cccaaagcac
     2941 tcattactac ttgcttcact ggaatcggta cggcggtcca cttaagtgaa ctgctagaaa
     3001 aaagcttacc tacggcttgt cagttgaaaa tcatcccata tgaatatcag caattaaaag
     3061 ataagaaaaa cagtgaccca ttattttcca tatacgaagt cgtaggaatg attggcacca
     3121 cagatcctga tatcaccaat atcgactatc tttcattaga agacctcatc tcgggggaaa
     3181 agatgtctgt actagctgaa tggttggaca ctactatgaa tgcttcagag aaggaaatat
     3241 tcaatcagcg catcattcgt aatttttcat tggaaaaagt actggattcc gtgactattc
     3301 tagatacaga gaaggtgatg ggagaaatcg atcattttat gagagaatta gaggtgcagt
     3361 tgaatcgaag catcagcaat cccaaaaaat tagcgttgta tgtccatgtg agctgtctca
     3421 ttgaacgatt gatccgacaa atgccaatcg aaacctatca aggattagag aaatggaagc
     3481 agtgtcaaaa agaagggtta tctgctatta aatctgcgtt tagtgtcatt gaagagcatt
     3541 atagtgtcat gatccccaat tctgagattg cctatatcta tgatattttg agtgaagata
     3601 cagagtttct ctcgatagaa gaagaatttt gaacataagc aagttgttgc cactaatttt
     3661 ggcatgcaac ttgctttttt agtatgtgta agtgaaaaga ggagatgaaa aagtggatag
     3721 agaaattatc ttagcttccc atggaaaatt tgcttcaggg atattagatt cattagagct
     3781 gatctatggg aaaaatcatt ctattactgt attcgattgc tatactgatg agaattttga
     3841 tttagcggaa acagtaaggc agctttttat gaggtacaaa gataaagaaa tcattgttct
     3901 gacggatctt tttggcggaa gtgtcaacaa cgaattctta caatatatca atcgggatca
     3961 tgtctatctc gttgccggat tgaatttgcc actattgatt gagctagtat ctcggttgga
     4021 cgctgaagta gagacaactg ttttgatcca gcaggtgcta actgattcaa aaaaaatgat
     4081 ccagttttgt aacgagcggc tcaatcagaa aatagaagaa gacgaatttt aggaggaaga
     4141 aaaatgattg tattgacaag agtcgaccat cggttattac acggacaagt agctttttca
     4201 tggacacaaa caataggcgc agactgtatt ttgattgcta atgatgatgt acctacgaat
     4261 gagatacgaa agacaacgat caaattagcc aagccacaag gagtcaaact agtgatcaaa
     4321 tcaattgatg actcgattgc cgcgttgaaa agcggggtga cagataaata taagttattc
     4381 atcgtagtgg aatcgatcga ggatgcatat aagctggcag aagcgtatcc agaaatcaaa
     4441 accatcaact taggagggat caaggcaaaa cctggtactc gcagcatcgg aaaagcggta
     4501 aatattttac cagaagagga ggaacgcttg aaacgattaa ttgacaaaca aatagaagta
     4561 gaaatccgtc aagtaccagc agataaaaaa gtggatgtaa gagaagtttt gtaagaaagg
     4621 aagaacctca atgattgtac aagcagtctt attaggaatt gttgcatttg tcgcacaatc
     4681 agaatatgca ctagggacat cgttgctttc tcgtccgatt gtgacggggc tgtttacagg
     4741 aatcgtgtta ggtgatgtaa aaactgggat cattatgggc gcaactttag agttagcatt
     4801 tatcggatcg ttctcagtag gtgcttcgat tccacctgat gttgtgaccg gtgggatttt
     4861 agggacggct tttgctatta cagctggagc cggtacagaa accgcgcttt tactaggttt
     4921 gccgattgct acgttgacat tgatattgaa aaatatttac ttagggcttt tgattccaat
     4981 tatgaaccat aaagcagaca attatgcaga agaaggaaat tataaaggag tcgagcatat
     5041 gcacttgctt gccggtatcg gtctttcctt gatgcttggt gttgtggtaa tggtttctta
     5101 tatggtggga agcaatacga tcggaaatct attaaatatg attcctgact tcgttcaaaa
     5161 ggggttgtca gtagctacag ggttgattcc agctcttggt tttgcgatgc ttgctcgttt
     5221 gctgatcaac aaacaagttg caccatattt tttcttaggt tttgctatag cttcttactt
     5281 agagattcct gtgaccggag tagctatttt tggtgcgatt ttagcagttg tggtagtcaa
     5341 tattatgaat gtccgtcaac taccacttca aacaactgca ggggaggtag aagaagatga
     5401 agaattctga gatcaaaaac agcaaaataa cgaaaaaaga gctaaatcac gtattttggc
     5461 gttcttttca aatggagttt tcttggaatt atgaacgtca gatgaatatg gcttatgttt
     5521 atgcaatgat tccgattttg aaaaagttat atcagtcgaa agaagaaatg gcagcagctt
     5581 tgaaacggca tctagagttt tttaacacga ccccacatat cgttacactg attttaggaa
     5641 tcacggctgc aatggaggaa gaaaataagg atgatcctga atttgatgtg actgcgatcg
     5701 atagtatcaa aacatctttg atgggacctc ttgcagggtt aggagattct ttcttttggg
     5761 gaactttgcg attgattgcc acaggtgtgg gtacctcttt agccatgcaa ggaaatattt
     5821 taggccctat cttgttcatt ttgattttca atattccgca cattctgttt cgctatctag
     5881 caacaggttg gggatatcgc ttaggaacgg gttttttgaa aaagatccag gcaaacggta
     5941 tgatggaaag tttgacatta ggcgcgtcta ttattggact gatggtcgtt ggagcaatga
     6001 ctgccacgat gatcaccatc aatattcctt taaaaatcgg ttcaggagaa aatgctgtga
     6061 ctgttcaaag tatttttgat gatatcgttc caaatatctt atgtcttgga gcatttggca
     6121 tagtgtttta tctattgaag aaagaagtga aaccattaac gatcttgatc ggactagctt
     6181 tctttggaat ttttggttcg tggataggga ttttttaaaa aaggagcaga gaaaatgttt
     6241 acgatgcaag attatatcta tgaagaaaag gaagtactaa gtacgatctt gaaaaagaat
     6301 gatttttcga caagagaaca tatgaaaaaa acagtgaatt tactgatctt agcaacgggt
     6361 tcatcttata acgcttgttt agcagcgaag ccagcattgg aatcttatgg tgatcttact
     6421 gtcgatattc aagaaccttt ttattttttc aattatggaa aactttctcc ttcaatcgat
     6481 actgtgattg ctgtgtcaca aagcgggaaa agtgcttcta ctgttgaagc agtaaaaatg
     6541 atacaaaaac aagggttacc tgttgttgct atcacaaatg acgtgcaaag tccacttgct
     6601 ttagaagctg cacaaattat tgatttaggt gccggggtag aatcagtagg cttcgttaca
     6661 aaaggctatt ctgcgactgt tttacagtta ctactcttag ggataggaat tggaataagt
     6721 aaaaataaaa tcagcaaaaa aatagaacaa gactacatgc aacagttgcg caaaataatc
     6781 aaccatttac cagcgattat tcaaaaaacg gaagaatttt ttgatggata tcaaagttta
     6841 tttcgtttag cacagcgttt cgtcaccatt ggatatggtc caaactgggg aacagctaaa
     6901 gaagcagaga cgaaattgac tgaaacaatc cgcgttccgt cacaaggatt tgagttagaa
     6961 gcttatatgc acggcccata cctggaggca gatgcttcgc atttgctatt ctttattgaa
     7021 ggggaaagtg taaataagga acgttcgcaa aagttgcaaa gatatatgag tcggtacgtt
     7081 ggagagactc tcaccattac cacaaaaaaa gcaagaaacg agaaaacact tggattagca
     7141 atagaatgtg atgaatatct gtctgtatta gcgcttgtcg ttccgtttca actattcgct
     7201 tataaaaccg cagtagctaa aggtattgac ttgaacaaaa agatttttga agactttgat
     7261 acagtcttga aaagtaaatt ataagaggtg gaaatcatgc tgaaattcaa tgaagaagaa
     7321 caaatcaaag caataaaagg cgcactagct ttacgtccgc aagtagaaga aatcatcgat
     7381 aaactttatg cggaaaaatt tgacgctgtc tattatctag gaatcggtgg aacgtatgct
     7441 tcctcgatgc aagctgtcac ttatatgaat gggaaaagca acttgcctgt ctttgtacag
     7501 catgctgcag aatattacac tactggaaac aaaagattaa caaaagattc tatcgttatt
     7561 ttgtcctctg ttaccggtac aactcaagaa gtagtgaaag cagtagaaca aatcaagaaa
     7621 gtaggagcga cactgattgg atttatcgat aaagcgaaca gtaagttgtc tcagctatgc
     7681 gattttgtgg tcacttatcc agctcctgga acagaacaaa tcaaattttt tatggcagca
     7741 gatcgattga tgtatttgaa tggagaattc gaagcttatt cagaatacta tgaacagctc
     7801 gaacgttatt taccaacagg gttagtggaa gcagagaaaa aagcagatgc atttggctta
     7861 tcatttgcag aaaaacatcg acgtgatagt atgcattatt ttattggagc agggaatcaa
     7921 tggggagctg tttattcata tgccatgtgt tactgggaag aacaaagctg gcttccatcg
     7981 aaatctatcc atgctgccga gtttcttcac gggacgttag agatcgtaga agaaacaacc
     8041 ccagtcacat tatttttagg cgaagatgaa cagagagtgt tatctgaacg tgtggctaaa
     8101 cttttgccaa aaatttgcag caattataca ttgatagaca caaaagacta tccagtagaa
     8161 ggtatcagtg aaaaatatcg cggacgtgtt ttgtctttct tattgatgca tgtagtgaca
     8221 caacgcatcg atgctcatgt ggagcagttg aactgccatc cattagagat acgccgctac
     8281 tatcgtcagt ttgattatta ggatagactg gataaaaaga atataaaaaa taaagagagc
     8341 agcgataact gctcccttta tttttttaaa atattggcat caattacgtt ataaaacaca
     8401 ttttttgcat tatctacagt tcaacttata atctgtttaa tgggacatgt gggtgccaac
     8461 cattttttgt tatgcaatag tactatttag ttgttgcatg gatccgtagt aaaagtccaa
     8521 gtacaacgag ttgcgccagt ttacatagcg ttttgtatcc agaatgttga ctaaaacaaa
     8581 agttcctatg tcaaccgtca acagagacaa tctgtccgtt gcaggacctg acagatttag
     8641 aaatgttcaa tctgtctctt atgtatttta aatcaatact cactaggaga agtttcctaa
     8701 cctcctaata gtaatgctgg tagtaacatt gtcaaaactg cttcctctta ggaacaagca
     8761 aagcataacg agtgtaaaaa taaaatgtag actattgtaa catatcattg attatttcaa
     8821 gtaaaaacga taaaagaagt aaacaaacac ttaaaaacaa tggaaattag tcccaacttt
     8881 aagaaatgta tactataatg gaaattatca attatttatt tggaggaata tccatgaaac
     8941 aaaaaatcgc agttcttggt cctggatctt ggggcactgc tttagcacaa acattggcag
     9001 aaaacgggca tgatgtccgt atttggggaa atgtacctga acagattgat gaaatcaata
     9061 agtatcatac aaatcagcat tttttacctg atttgacgat cccagaatcg attatcggat
     9121 ataaagaatt ggcagaagca gtggataacg cagatgctat tttatttgtt gttccaacaa
     9181 aagcgattcg ttcagtcgca caggaactta ttggtaaaat gaatactaag ccaatcatta
     9241 tacatgcaag taaaggacta gaacaagata cgcataaacg aatctcagaa gttttggctg
     9301 aagaaattcc agaagaaaaa agacaggcaa ttgttgtatt atctggtcct agccatgctg
     9361 aggaagtggc agtacatgat atcacaacaa ttacagctgc aagtattgat caaaaagcag
     9421 cagcctatgt acaaaaactg ttcatgaatg attatttcag gatttataca aataatgatg
     9481 tgattggcgt agaaactggt gcagcactga aaaatatcat tgcaattggt gccggcgcta
     9541 tccatggatt aggattcgga gatgatgcaa aagcagcaat catgactcga ggattggcag
     9601 aaatcagccg tcttggtgtc gcgatgggtg ccaatcctct gacatttatc ggtttgagtg
     9661 gtgtggggga cttgatcgtt acttgtacaa gtgttcattc tcgcaattgg cgtgccggta
     9721 acttgttagg acagggacat aagctggaag aagttctaga aaacatggga atggtcgttg
     9781 agggtgtggc aacgacaaaa gcagcagtag agctagctca acagctaggt gttgagatgc
     9841 caattactca aacaatctat aatgttttgt ataatggaga agatatcaaa aaagcagcaa
     9901 aagaaatcat gttacgtgac ggaaaaatgg agaatgaatt ttctcttcgt taaatagatg
     9961 atcaatagtt aatcgt
//
LOCUS       DAZKKZ010000084         9941 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.086, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000084 DAZKKZ010000000
VERSION     DAZKKZ010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9941)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9941)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9941
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.086"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..1189
                     /locus_tag="ACG8LA_002524"
     CDS             <1..1189
                     /locus_tag="ACG8LA_002524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HFQ0204795.1"
                     /translation="IYKGTLLYKPEECSHCLCVVPSRIIRWGTTTVRLLLNDASEYRT
                     YLELKKQRFKCKSCQRTFVADTSVAEKHCFISQKVRWSVIARLKENTSMTEIARQKNI
                     STSSVYRVMKRFYRPLNPFKQALPKVLCFDEFKSVRSVASAMSFIMMDGQSHALLDIV
                     ENRRLPYLECYFSRFSLATREAVQWIVIDMYAPYVSLVKKLFPNAQLIIDRFHIVQHI
                     GRTFLNHRVKETTARLKGTSHSQRGLGKKLKRYWKLLQKEEAKLNYEKRVWRASFKDY
                     LTESEIVDRLLSACPNLRQGYQLYQDILYAVKKRDQSLFEDCLNREVSGLPETYTTTL
                     RTFKKFLPQIQNALHYSYSNGPLECLNNHIKVLKRNAYGFRSFYNFKLRIMIRHGKTF
                     LTK"
     gene            1309..1509
                     /locus_tag="ACG8LA_002525"
     CDS             1309..1509
                     /locus_tag="ACG8LA_002525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="HFQ0204796.1"
                     /translation="MIEEEQKNIWDRYYKADPSSKNTKIGESGLGLSIVKELVRLHHG
                     SIEVTSRKNEGTTFLIQFPKEK"
     gene            1585..1782
                     /locus_tag="ACG8LA_002526"
     CDS             1585..1782
                     /locus_tag="ACG8LA_002526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204797.1"
                     /translation="MVECLKNKKMEANFVKAVISGSIVFQEEYRDMEKDFSKKGIELI
                     DYPRSCPILDKEYPEILTTFF"
     gene            complement(2079..3626)
                     /locus_tag="ACG8LA_002527"
     CDS             complement(2079..3626)
                     /locus_tag="ACG8LA_002527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008253 - 5'-nucleotidase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-sugar
                     hydrolase/5'-nucleotidase"
                     /protein_id="HFQ0204798.1"
                     /translation="MNITFLETSDMHGYVSPTDYSGRTDLALGTAKVSSKLKELRAKA
                     DGPVITIENGDFIQGSPLSYYLAKEYGSAKELTDLINQMSYDVQVLGNHEFNYGVDYL
                     EEAIKNYQAPILGANMVNKNDQPYFGNAYKIIEKVGVKIAILGLTTQYIPHWEKPETL
                     AGITFKSIVETAKEYVPLLRKQADLVIVSYHGGFEKDLLTGEDTEALTGENEGYELLQ
                     QVEGIDALFTGHQHRKIAETVHGVPVVQPGYRGEFIGEIRLTVEKKEGQVVVTDHQVA
                     LHSVEKSEPDPEILAAIVPVEEKLEKWLDQPLGKVNGNMRINDPMQARLEEHPYVEFI
                     NRVQLFASGSEISGTALFNNEGKGFGETITMRDVITNYIYPNTLAVIQINGADLRAAL
                     EQTANYLAVENNQIVFNPAFIQPKPQYYNYDMYEGIQYTIDMKQPVGQRITELRFKGH
                     PVLPQQMLEVVTNQYRAIGGGNYAMFGAEKIVREIQIDMTELIADYLNIHPRIEAKVN
                     HNFQVIL"
     gene            complement(3710..4513)
                     /locus_tag="ACG8LA_002528"
     CDS             complement(3710..4513)
                     /locus_tag="ACG8LA_002528"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HFQ0204799.1"
                     /translation="MNILHISDIHFRREYEACEEGYKGMLATMQNPLIPLEQCIHHLL
                     QQTPLDLVIISGDLTEDGEIDDYRYLKTWLENALGETTILVTLGNHDIKEHFWVGWCD
                     EAASSAPYNQIVKYPEFTVISFDNSSYGYADGIVDDQQFQWLKKALEQEKDQPIFLVT
                     HHHLLSHQSSIPKWPGTERFLKLIAPYDIRCILNGHTHHTFTDEINGIPYFTVSSMSF
                     VGEDEGDGFVRFEERHGYNLYHLDQGRIVRQTTENFIPGNILKTLQMKD"
     gene            complement(4516..5298)
                     /gene="phnE"
                     /locus_tag="ACG8LA_002529"
     CDS             complement(4516..5298)
                     /gene="phnE"
                     /locus_tag="ACG8LA_002529"
                     /EC_number="7.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005233297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015416 - ABC-type phosphonate transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015716 - organic phosphonate transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate ABC transporter, permease protein
                     PhnE"
                     /protein_id="HFQ0204800.1"
                     /translation="MMLREMNRRTLLSLVALVILVILSAATLDYSGLSTFSPSMGMDV
                     LRGLGQPDWQFLYDGSGEDLISLLLLTIGIACLGTMIATVLAIPITLISAVNLWQAHP
                     WVTKIGKLICNVLRAFPELVFAIIFVKVVGPGPFAGVMAIGVHQIGMLGKLFTEEMEA
                     MDERLVEEMHAVGANFWQTIFFVRIPYLMPIYCSLALNHFEIAVRSAATLGLVGAGGI
                     GAPLIFAIQTRSWSKVSIILIGVVVTVFILDQITGIIRKRLR"
     gene            complement(5295..6074)
                     /gene="phnE"
                     /locus_tag="ACG8LA_002530"
     CDS             complement(5295..6074)
                     /gene="phnE"
                     /locus_tag="ACG8LA_002530"
                     /EC_number="7.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010743453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015416 - ABC-type phosphonate transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015716 - organic phosphonate transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate ABC transporter, permease protein
                     PhnE"
                     /protein_id="HFQ0204801.1"
                     /translation="MSLKETVHFKWYKHLLILLFLIVCFQGSAWITSADFSQVFQNSN
                     QMTVFLSRFIHPDFSYLPKLVEPMVKTLQMSLLGTVIGLILAIPVSFLATTVVTENRL
                     LSTIFRFLLGLVRTIPTLLLAALFVAVFGIGEATGVLTIAVFTFGMVSQLMFQAIETI
                     DFGPIEAAAAVGANKMQIAIWSIAPQVLSQFASYAFYAFEVNVRASTVLGYVGAGGIG
                     VILNSSLALLNYERVSIIILTILVTVAIVDKLSERVRRSLL"
     gene            complement(6046..6837)
                     /gene="phnC"
                     /locus_tag="ACG8LA_002531"
     CDS             complement(6046..6837)
                     /gene="phnC"
                     /locus_tag="ACG8LA_002531"
                     /EC_number="7.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015416 - ABC-type phosphonate transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015716 - organic phosphonate transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate ABC transporter ATP-binding protein"
                     /protein_id="HFQ0204802.1"
                     /translation="MIIFDNVSKVYPNGVVGLKDIDLTIEDGEFVSIIGLSGAGKSTL
                     LRSINRLAETTKGDIRINGTSITKANKKELRQIRRQIGLISQSFNLVKRSTVQKNVLS
                     GRLGYYSTWKSILGLFTKEDYQQTKEALEKVGLSDKLQTRSDELSGGQQQRVSIARAL
                     VQQAPIILADEPVASLDPITTQKVMMDLKNINQTMDKTVIVNLHSVPLAREFSTRVLA
                     LKAAQVVFDGRPDDLTDERLEQIYGNAIFEEKAGEIDELERNRSL"
     gene            complement(6898..7827)
                     /locus_tag="ACG8LA_002532"
     CDS             complement(6898..7827)
                     /locus_tag="ACG8LA_002532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010743455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate/phosphite/phosphonate ABC transporter
                     substrate-binding protein"
                     /protein_id="HFQ0204803.1"
                     /translation="MQFKQLAKGFIGVMLLTTLAACGSGNTSSSSEKESKEKLVVQFV
                     PTNNDGSMEAKAKPFAKYLSKKLDREVEVTLATDYSTIVEAMSSGQVDVGIMPPAAYV
                     QAKDAGAADAILTSQLGDYDQETGLPLKDKLTNTFKGEVLVRADSGLNKLTDLKGKNI
                     ATLSPNSASGYIYPVAELKDAGIDPTADTKMTTVNDIPSEITAVLNKQMDAAFVFEGA
                     RNVFASNFPDNDLFKDLKVLYLTKGDIPNDAIAVQPDMSKDLKAKIKETFLNMKDDKD
                     GKEAMALWGHQGYEEAADSAYDTIRDYTKKAAE"
     gene            8022..8705
                     /locus_tag="ACG8LA_002533"
     CDS             8022..8705
                     /locus_tag="ACG8LA_002533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic nucleotide-binding domain-containing
                     protein"
                     /protein_id="HFQ0204804.1"
                     /translation="MKKIHDTKQLTAYVEKHNLQDYMDSDILAMASLLFFEKEEHLIQ
                     TGKTSDYLYFLVDGTVMVYSYSSDTQNICIDYAKPATPLGEASSLWELSPKSSVKAVT
                     KCICISIPLNQYRTQLQKDVRFLQNICQLLSYRLNSGINLANSLTEPVETRLAKFILT
                     HHENERFSFRLTTCASILNVSYRHLLRTITNFREENIIEKKKNYYLIHDIEALEDLAE
                     NISSPVKAE"
     gene            8866..9909
                     /locus_tag="ACG8LA_002534"
     CDS             8866..9909
                     /locus_tag="ACG8LA_002534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HFQ0204805.1"
                     /translation="MKKILVSLLFLVSLVTLVGCSQSQGEKQSEKEKSKIALVLGFGG
                     VDDRSFNQAGWEGLEAWGKEKKLTAKKDFTYIETNNPEDNSTNIDQAIRNGFTTIISL
                     SYLQAEELENAAKDNPKLKFALVDGEITGKKNISSATFKDQESAYLAGLAAAYTTKSD
                     QVGFIGGMEGPVIQRFQSGFEAGVKAGATALNKEITVNVQYAASYDSLDKGKAIAASM
                     YKEGVDILYQAAGSTGAGVFQEAKARNENDYSRKVWVIGVDRDQADEGDYKMENGETG
                     NFTLTSTKKNVGAEVKEFAETSHNDKFPGGKHLTFGLKEEGVDLTKGQLSEEAYQAVS
                     DAKEKIISGDFRL"
BASE COUNT         3032 a         2036 c         1978 g         2895 t
ORIGIN      
        1 gatttacaaa ggaactcttc tgtacaagcc agaagagtgt tcccattgtc tttgtgtcgt
       61 cccctctagg atcattcgtt gggggacgac aaccgttcgg ttgttactga atgatgcgtc
      121 tgagtatcgc acttatctgg agttgaagaa acaacgattt aaatgtaagt cttgccaaag
      181 aacattcgta gcggatacct ctgttgctga aaaacactgt ttcattagtc aaaaagttcg
      241 ttggtctgtc attgctcgct taaaagagaa tacttccatg acggaaatcg ctcgtcagaa
      301 aaatatttcc acttcttcgg tctatcgtgt catgaagcga ttctaccgcc cattgaatcc
      361 tttcaaacag gctttgccaa aggtcttatg ctttgatgaa ttcaaatcgg ttcgaagtgt
      421 tgccagtgca atgagtttta tcatgatgga cggacaaagc catgcattat tggatattgt
      481 cgaaaatcga cgcttgcctt atttagaatg ctatttttct cggttttcat tagcgactcg
      541 tgaagccgtt caatggattg ttattgatat gtatgcgcct tatgtttcat tggtgaaaaa
      601 gcttttcccg aatgctcagt tgatcatcga ccgtttccac atcgtccaac atattggcag
      661 aaccttcttg aatcatcgag tgaaagaaac cacggcacgg cttaaaggaa cttcccactc
      721 tcaacgaggg ttagggaaaa aattgaaacg ctattggaaa ctcctacaaa aagaagaagc
      781 aaagttaaac tacgaaaaaa gggtttggcg tgccagtttt aaagattatt tgactgaaag
      841 tgagattgtc gatcgactgt tatctgcttg tcccaacctg cgccaaggct atcagttata
      901 ccaagacatt ctttatgcgg taaagaaaag agatcagtca ttatttgagg actgtttaaa
      961 cagagaagtc agcggtcttc ctgaaaccta tacaaccact ttacgaacgt ttaaaaagtt
     1021 tctgccacag atccaaaatg cgcttcacta cagctattca aatggaccat tggaatgttt
     1081 aaacaaccac atcaaagtat taaaacgcaa tgcgtacggc tttcgcagct tttacaattt
     1141 caaactacgg atcatgattc gtcatggcaa aacattttta accaaataaa cagaacagaa
     1201 agagagtttc ttctttctgt tctgtccaaa ttattctaag atttctcttt accaacatca
     1261 tttgacaaag agcctgtatt tattactgtc gaggacaatg gcatcggcat gattgaagag
     1321 gaacaaaaaa acatttggga tcgctattat aaagccgatc cgtcaagtaa aaatacaaag
     1381 ataggcgagt caggtcttgg attatcaatc gtgaaggaac tagtgcgcct gcaccacggt
     1441 tcaattgaag tgaccagccg aaaaaatgaa ggaacgacct tcctgataca atttccaaaa
     1501 gaaaaataaa attaccagta aaaaaccgtg gagagatagc tgctattgat ttttgctatg
     1561 tcttttcttt gagaggtatc cggtatggtg gagtgtctga aaaataaaaa aatggaggcc
     1621 aattttgtga aagctgttat ttctggaagt attgttttcc aagaagaata tcgagatatg
     1681 gaaaaagatt tcagtaaaaa aggcattgaa ttaattgatt atcctcgctc atgtccgatc
     1741 ctagacaaag agtatccaga aatcttgacg actttttttt aaatatcgca gcagcggatt
     1801 tattttttgt atttaatcaa gatcggaaag gggtattagg ctatattggt gccgcaactt
     1861 tttcagaaat gaagtattgt ctgatgcaaa atcttattca tggaaaaagg atcaaaatag
     1921 tcttatttaa ggaaccatca gaggaaaatt ttttgttttg atgaggtaga tcgctggcta
     1981 aagaatggct ggatggaaat cagacagcct aacaatttgg cataacaaag gtgtgggcaa
     2041 aaaactgctc acaccttttt gaatttttta tttatatact acaaaatcac ttgaaaatta
     2101 tgattcactt ttgcttcgat gcgtgggtga atattcaaat agtcggcaat taattcggtc
     2161 atgtcgattt ggatttctcg gacaattttc tccgcaccaa acatcgcata atttcctccg
     2221 ccgattgccc gatattgatt tgtcaccact tccagcattt gttgcggaag aacggggtga
     2281 cctttaaaac gaagttcggt aatccgttgt ccaacaggct gtttcatatc aatagtgtac
     2341 tgaatccctt catacatgtc ataattgtag tactggggct taggctgaat aaaggctgga
     2401 ttgaatacga tttggttatt ttctacagct aaataatttg cggtctgctc caacgccgct
     2461 ctcaaatctg caccatttat ttgaatcact gccagagtat tcggataaat atagttggtg
     2521 atgacgtccc gcatcgtgat cgtctcacca aagccttttc cttcattatt gaataacgca
     2581 gttccagaaa tctctgagcc gctggcaaat aattgtacac gattaataaa ctctacatag
     2641 ggatgttcct caagacgagc ctgcatcgga tcattaatac gcatatttcc gttcacttta
     2701 cctaagggtt gatccaacca tttctctagt ttttcttcta ccggtacgat cgctgcaaga
     2761 atttctggat caggctctga tttttcaact gagtgtaaag caacctggtg atctgtaaca
     2821 accacttgcc cctctttttt ctcgacggta agacgaattt caccgatgaa ctcgccacga
     2881 tagcctggtt gaacaacggg aactccatga accgtttcag caattttccg gtgctgatga
     2941 ccggtgaaaa gggcgtcaat gccttcaacc tgctgcaata gctcgtagcc ttcattctct
     3001 ccagttagcg cttctgtgtc ctcaccggtt aacaagtctt tttcaaatcc gccgtggtaa
     3061 ctaacgatta ccaagtctgc ttgtttcctt aatagaggaa catattcttt tgctgtttcg
     3121 acgatactct taaacgtaat tcctgctaag gtttctggct tttcccagtg aggaatgtat
     3181 tgtgtcgtta atcccaagat agcaattttt acacccacct tttcgataat cttataggcg
     3241 tttccaaagt atggttggtc atttttgttc accatattgg ctcctaatat aggcgcttga
     3301 taattcttaa tcgcttcctc gagataatcc acaccatagt taaactcatg atttcccaac
     3361 acttgaacat catagctcat ttggttaatc aagtctgtaa gctctttggc tgaaccatat
     3421 tctttagcaa gataataact caaaggagac ccttggatga aatcaccatt ttcgatcgta
     3481 attaccggtc catctgcttt tgcccgtaat tccttcagtt tcgacgatac tttagccgtt
     3541 cctaaggcca gatcggttct gccggaatag tctgttggtg aaacatagcc atgcatatca
     3601 cttgtctcta aaaacgtaat gttcattctg cgtgctcctt tagctgactc aaaatagaaa
     3661 aaccgaagcg tattcagctg ttcggtctct ttttttgatt tataatgcct taatccttca
     3721 tttgaagtgt ttttaaaatg ttgcctggaa taaagttttc tgttgtctgg cgaacaatcc
     3781 ttccttgatc gagatgataa aggttatacc catgacgttc ttcaaagcgt acgaagccat
     3841 cgccttcatc ttcaccaaca aaggacatac tcgatacagt aaaatagggg atcccattaa
     3901 tttcatcagt aaatgtgtga tgggtatgac cgtttaggat acagcgaata tcgtaaggtg
     3961 cgattagctt caagaaacgt tcggtaccag gccattttgg tatactgctt tggtgagaca
     4021 gtagatgatg atgggtgacc aagaaaatcg gttggtcttt ttcttgctct aaggcttttt
     4081 tcagccattg aaattgctga tcgtccacta taccatctgc gtatccatag cttgaattat
     4141 caaaggaaat cactgtaaac tcaggatatt tgactatctg gttgtacggg gcagaagagg
     4201 cggcttcatc gcaccagcct acccaaaaat gttctttgat atcgtgattg cctagagtaa
     4261 caagaatcgt cgtttctcct agcgcatttt ccagccaagt cttcaagtat cgataatcgt
     4321 ctatttcgcc atcttcggtt aaatctccgc tgataatcac aaggtccaag ggtgtttgct
     4381 gcaggagatg atgaatgcat tgctccagag ggataagggg attctgcatc gtagccagca
     4441 ttcccttata gccttcttca caagcctcat actctctgcg aaagtgtata tctgatatat
     4501 gcaatatatt cattcttatc tcaatctctt tcttataatt ccggttattt gatctaaaat
     4561 aaacacggtt acgactacgc caatcaaaat aatactcact ttgctccaag accgagtttg
     4621 aatcgcgaat atcaatggag caccgattcc gccagcgcca actaagccta aggtagccgc
     4681 actacgaacc gctatttcaa aatgatttaa tgctaaagaa caataaatcg gcatcaaata
     4741 ggggatgcga acaaagaaaa tcgtttgcca aaaatttgct cctaccgcat gcatttcttc
     4801 aacaagtcgc tcatccatcg cttccatttc ttctgtaaaa agtttgccaa gcattccgat
     4861 ctgatggacg ccaatcgcca taacaccagc aaaggggcca ggtccgacga ctttcacaaa
     4921 aataattgca aaaactagtt caggaaaagc tcgtaaaaca ttacagataa gcttgccaat
     4981 ttttgttacc catggatgtg cttgccagag gttaaccgca ctgatcaagg taatgggaat
     5041 cgctaatacc gtagcgatca ttgtccctaa acaggcgatt ccaatggtta ataatagcaa
     5101 actaatcaaa tcctcgccgc tgccatcata tagaaactgc caatcaggct gacctaaccc
     5161 tctcaaaacg tccattccca tggaaggaga gaaggtgctt aatccagagt aatccagagt
     5221 agcggccgac aaaataacga gaatcactaa agcaactaat gataaaaggg ttcttctgtt
     5281 catttcacga agcatcataa cagggacctc ctgacacgtt cacttaattt atcaacgatc
     5341 gcgacagtta ctaggatcgt tagaataatg attgaaactc gttcataatt caaaagcgca
     5401 agtgaggaat ttagaataac gccaatacca ccagctccga catatccaag gacagtagaa
     5461 gcacgaacat tcacctcaaa cgcgtaaaaa gcatagctcg caaactgact caaaacttgt
     5521 ggagcgatcg accaaatagc gatttgcatt ttatttgctc caacagccgc agcggcttca
     5581 atcgggccaa agtcaatggt ttcaattgct tgaaacatta attgtgacac cataccaaaa
     5641 gtaaagacag cgatagtcaa cacgccagtc gcttcaccaa ttccaaacac agcaacaaaa
     5701 agcgcggcta aaagcagggt agggatggtc cgtactaaac ctaaaagaaa acgaaagatg
     5761 gtagaaagaa gacggttttc tgtcactaca gtggtcgcta aaaaactaac agggatcgct
     5821 aaaattaagc caatgaccgt tccaagcaaa gacatttgaa gtgttttcac cataggctcg
     5881 actaatttag gtaaatagct aaagtctgga tgaatgaagc gtgataaaaa gacagtcatt
     5941 tgattggagt tttgaaaaac ctgagaaaaa tcagctgacg tgatccaggc acttccttga
     6001 aaacaaacaa ttaagaacag aagaataagc aggtgtttat accatttaaa gtgaacggtt
     6061 tctttcaagc tcatcgattt cgcctgcctt ttcttcaaag attgcattgc cataaatttg
     6121 ctctaagcgt tcatcggtta agtcgtctgg acgaccatca aagacaacct gagcagcttt
     6181 taacgcgagc acacgcgtag aaaactcacg agccagaggg actgaatgca gattgacaat
     6241 gactgtttta tccatcgttt gattgatatt ttttaggtcc atcataacct tttgagtcgt
     6301 gattggatct aatgatgcaa cgggttcatc cgctaaaata atgggggctt gctgcacgag
     6361 tgctcgcgca atggatactc gctgttgttg cccaccactg agctcatcac tgcgtgtctg
     6421 caatttatca gacaaaccaa ctttttccag tgcttccttt gtctgctggt agtcttcctt
     6481 cgtaaaaaga cctaaaatac ttttccaagt ggagtaatag cccaaacgtc cagatagcac
     6541 atttttctga accgtactac gctttaccag attgaagctt tgcgagatta gaccaatctg
     6601 gcggcgaatc tgtcgcagct cttttttatt cgcttttgta atagaggttc cattaatgcg
     6661 aatatctcct ttggtggttt ctgccaagcg attgatactg cgcagcagag tgctctttcc
     6721 agcaccactc aaccctatga tggaaacaaa ttctccatct tcaattgtta agtcaatatc
     6781 cttcaagcca acaacgccat tgggatagac cttcgaaaca ttgtcaaaaa taatcattat
     6841 ccttctccat ttttttaagt gtaagcaaaa aaaagcttgc tgacacttac tgatgtttta
     6901 ttctgctgct tttttcgtgt agtctctgat cgtgtcatag gcagaatcag cagcttcttc
     6961 atagccctga tgcccccaca aagccattgc ttctttgcca tctttatcat ccttcatatt
     7021 taagaaggtc tctttaattt tcgcttttaa atcttttgac atgtcaggct gtacagcgat
     7081 tgcgtcattc ggaatatcgc cttttgtcag gtacaggact tttaaatcct taaataaatc
     7141 attatctggg aaattcgaag caaaaacatt tcgcgcgcct tcaaaaacaa acgccgcatc
     7201 catttgcttg ttcaacactg cggtaatctc actcggaata tcattcacag tggtcatctt
     7261 tgtatctgca gtaggatcaa tcccagcatc tttcaattca gcgacaggat agatgtagcc
     7321 gctagcagag ttaggactta aggttgcgat attttttcct tttaaatcag ttaacttatt
     7381 caatccgcta tcggcacgaa ccaatacttc tcctttaaag gtgttcgtaa gtttgtcctt
     7441 taatggcaag ccagtttctt gatcataatc gccgagctga gaagtcagga ttgcatctgc
     7501 agctccagca tcctttgctt gaacataggc tgcaggcggc ataattccga catcgacttg
     7561 accagaagac atcgcttcga cgatcgttga ataatcagta gctaacgtca cttctacctc
     7621 acgatctaac tttttcgata aatacttagc aaatggtttt gcttttgcct ccatactacc
     7681 atcattgttt gttggaacga attgaacaac taatttttct ttgctctctt tttctgagct
     7741 gctacttgta ttcccagaac cgcaggccgc caaagtggtc aataacatga ctccgatgaa
     7801 cccttttgct aactgtttga actgcatttt tctcctcctg ttggatataa tttctaatac
     7861 gtctaaatca tagcagggaa tcaaaatcaa tgaagtgacg cacgtcctat tttacacaac
     7921 ttttacatac aatttacaaa caattataaa taattattcg tattgagccg aaaaacaatc
     7981 taagctataa taaagaaaaa cttcttagag gtgacgattt catgaaaaaa atccatgata
     8041 cgaagcaatt aactgcttac gttgagaagc acaacctgca ggattatatg gattcagata
     8101 tattggcaat ggcttcttta cttttttttg aaaaggaaga gcacctcatt caaacgggaa
     8161 aaacctcaga ttatttgtat tttttagtgg atgggacggt aatggtgtac tcgtattctt
     8221 ctgatacaca aaatatttgc atcgattacg caaagcccgc tacaccactc ggcgaagcct
     8281 cttcattgtg ggaattatcg ccgaaaagca gcgttaaagc agtgactaag tgcatctgta
     8341 tcagcattcc gctaaatcaa tatcgaacac agcttcaaaa agatgttcgc tttttgcaga
     8401 atatttgcca gttactaagt tatcgtttaa attccgggat aaatttggcg aactcactga
     8461 cagaacctgt tgaaactcgt ttagcaaagt ttattttgac ccatcacgaa aacgaacgtt
     8521 tctcatttcg gttaaccacc tgcgcctcaa tcttaaatgt cagttatcga catcttttac
     8581 gaacaatcac gaattttcgt gaggagaata ttatcgaaaa gaaaaagaat tattacttga
     8641 ttcatgatat cgaagcttta gaggacttag ctgagaatat aagtagtcca gtaaaagcag
     8701 aataacagct ataaaaaaac agcagtcaga agtgattgct ggttttttga tagtggagaa
     8761 attgggaaac ggaaaatctt cgttgaagag tagtgttcta tatattggta tgctatactt
     8821 ttaaaagttc aatgtgtcaa gacacataaa aaggggagaa aaattttgaa gaaaatactt
     8881 gtttcattgt tgtttttggt gtcattagta acgttagtcg gctgtagtca gtctcagggg
     8941 gagaagcaaa gtgaaaaaga gaaaagtaaa atcgctttgg ttcttggatt tggcggggtt
     9001 gatgaccgct ccttcaatca agctggctgg gaaggattag aggcttgggg aaaagagaaa
     9061 aagctgacag caaaaaaaga ttttacgtat atagaaacga acaatccaga ggataacagt
     9121 accaatatcg atcaggcaat cagaaacggc tttaccacca ttattagctt gagctacttg
     9181 caagcagagg aactggaaaa tgctgctaaa gataatccaa agttgaaatt tgccttggta
     9241 gatggtgaga ttactgggaa aaagaatatc tcatcagcaa cctttaaaga tcaagaaagt
     9301 gcgtatttag caggactagc tgccgcatat acgacaaaaa gtgatcaagt aggctttatt
     9361 ggtggaatgg aagggcccgt gatccaacgt ttccaaagcg gatttgaagc tggcgttaag
     9421 gcaggggcca cagcactgaa caaggaaatt actgttaacg tacaatatgc tgcatcctat
     9481 gattcgctag ataaaggaaa agctattgct gcttctatgt acaaagaggg agtcgatatt
     9541 ctttatcagg cggcaggaag tactggagct ggggtgttcc aagaagcaaa agcccgcaat
     9601 gaaaacgact atagcagaaa agtatgggtg attggtgtag atcgcgatca agcggatgaa
     9661 ggggattata aaatggagaa cggcgagaca gggaatttca cgttgacttc tacaaagaaa
     9721 aatgtcggtg cagaagtcaa agaatttgca gaaacttctc ataacgataa atttcctggc
     9781 ggcaagcatt tgacctttgg tttgaaagaa gaaggggtag atctgacaaa aggacaatta
     9841 tcagaggaag cctatcaggc agtttcagac gcaaaagaga aaatcatcag tggtgatttc
     9901 agactgtaga caaagtccat tttatggatg atgtctacag t
//
LOCUS       DAZKKZ010000085         9873 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.087, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000085 DAZKKZ010000000
VERSION     DAZKKZ010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9873)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9873)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9873
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.087"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(22..267)
                     /locus_tag="ACG8LA_002535"
     CDS             complement(22..267)
                     /locus_tag="ACG8LA_002535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HFQ0204806.1"
                     /translation="MPTTLASIKKDLEGRIGSPIMLVAQTGRKRQTERRGVLTETYPS
                     VFVVDLDPEENSFERVSYSYSDVLTRTVEIEFLTEAV"
     gene            complement(381..959)
                     /locus_tag="ACG8LA_002536"
     CDS             complement(381..959)
                     /locus_tag="ACG8LA_002536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HFQ0204807.1"
                     /translation="MSEELLRAARNGDEEAFAALYQKYFPLLLRLKNTYYLRNYVSED
                     WEQEARIALYQALRTYEKSKGVSFGSYYKSIISNQIYSLLRKQNALKRRDQKDEVSID
                     QKIETEGPDFLAEITLQEPLAIQHLLLKEAIENCEIQFSKIEAKIFHYYMQGVDFVDM
                     AECLAMDHKQVMSAYGRVKLKIKKHLKFYNEE"
     gene            complement(1036..1566)
                     /locus_tag="ACG8LA_002537"
     CDS             complement(1036..1566)
                     /locus_tag="ACG8LA_002537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HFQ0204808.1"
                     /translation="MKKQLLIVDGYNMIGSWPELVQLKKQDKMADAREALLHRLSNYA
                     KYEGMEVIVVFDAQLVPGIQQNYKKYQLDVVFTKEDETADSYIERIAGQLNDRLTQVT
                     VATSDLAEQWMIFSQGALRTSAYELYKTIKKTEKTIAQENKDMHFIDFRRNSPWNEEQ
                     LKKLSQKLDDLMRKNK"
     gene            complement(1570..2430)
                     /gene="rlmB"
                     /locus_tag="ACG8LA_002538"
     CDS             complement(1570..2430)
                     /gene="rlmB"
                     /locus_tag="ACG8LA_002538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HFQ0204809.1"
                     /translation="MGKERTNKHQSKRGFEDKKQNRYSNKKQTGRNQSVSDQNEEALE
                     DNFVFGHHAAVEALQQGRGNKLFLQEDSRGEKVEELKEIAREQAVPVKWVPKQKLETL
                     SDHGVHQGVVLAITPYEYLSLDQLIERTKEKKEDPFFLILDSIEDPHNFGSILRTADA
                     SGVDGVIIPKHRAVGITPIVTKTSTGAVEHVPVARVTNLVQAVQQLKETGFWVFGTDM
                     TGTNFQKWNAKGSIALVIGNEGKGMSPGLKKEMDELLTIPMTGHVQSLNASVAAGLLM
                     YQAFSQRQGE"
     gene            complement(2423..2818)
                     /locus_tag="ACG8LA_002539"
     CDS             complement(2423..2818)
                     /locus_tag="ACG8LA_002539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HFQ0204810.1"
                     /translation="MRDYTQLNGLALAYVGDAIYEIYVRDHLIDQGETKPNKLHRAAT
                     NYVSANAQAFLIQQMLEEHLLTEEEELYYRRGRNAKSHTSAKNADVTTYRVATGFEAL
                     MGYLHLTKQTERMEELIRWCIQKVGEKNG"
     gene            complement(2815..4227)
                     /gene="cysS"
                     /locus_tag="ACG8LA_002540"
     CDS             complement(2815..4227)
                     /gene="cysS"
                     /locus_tag="ACG8LA_002540"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004817 - cysteine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006423 - cysteinyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HFQ0204811.1"
                     /translation="MIKIYNTLTRKKEEFIPIQKGHVGMYVCGPTVYNYIHIGNARST
                     IAFDTIRRYFEYRGYKVDFVSNFTDVDDKIIRTANELGITAPEVADRFIRAFEEDTKA
                     LNVEPATLHPRVMDHMPDILAFIQVLVEKGYAYESSGDVYYRTRKFENYGKLSDQSID
                     ELEVGASQRTGEEQQQKEDPLDFALWKQAKPGEISWDSPWGKGRPGWHIECSVMATKH
                     LGETIDIHGGGQDLEFPHHENEIAQSEAKTGKKFANYWMHNGYVTIGEDDEKMSKSLG
                     NFITVHEMIKNVDPQVLRFFMATTQYRRPIRYSETTMKEAATNLQRLKNTFDNLKFRQ
                     ETASENLADDADKIALLENLEQRFIEEMDDDFNAANGITVVYELAKWLNTYLDQPKVS
                     AAVLAQGEALFSQWLSIFGILFTAEELLDEEIEQLIEERNQARSNRDFVRSDEIRDLL
                     KEKGILLEDTPQGTRWRREA"
     gene            complement(4224..4760)
                     /gene="epsC"
                     /locus_tag="ACG8LA_002541"
     CDS             complement(4224..4760)
                     /gene="epsC"
                     /locus_tag="ACG8LA_002541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009001 - serine O-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase EpsC"
                     /protein_id="HFQ0204812.1"
                     /translation="MSWFTRAIDAAKRNDPAARSTAEIVLTYPGFHALFWHRFSHFLY
                     QHRLFLLAKINAQFWRFLTGVEIHPGATIGTGVFIDHGMGIVIGETAEIEDDVILFHG
                     VTLGGTGKETGKRHPTVKQGAMLSANAQILGPVTIGKNAKIGAGAVVLKDVPDDATAV
                     GVPAKVVRIKGEKVRRSE"
     misc_binding    complement(4846..5085)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(5082..6542)
                     /gene="gltX"
                     /locus_tag="ACG8LA_002542"
     CDS             complement(5082..6542)
                     /gene="gltX"
                     /locus_tag="ACG8LA_002542"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004818 - glutamate-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HFQ0204813.1"
                     /translation="MTKVRVRYAPSPTGHLHIGNARTALFNYLFARHNDGDFIIRIED
                     TDQKRNIEDGEKSQLENLAWLGMNWDESPENPGEYGPYRQSERKEIYQPLIDQLLASN
                     RAYKCYCTEEELEAEREAQRARGEMPHYAGTCANLTPEEQAEKEAQGLESVVRFRVPR
                     NTEYAFTDMVKGAISFESDNIGGDFVIQKRDGMPTYNFAVAVDDHLMKITHVLRGDDH
                     IANTPKQLMIYEAFGWTPPTFGHMTLIINSETGKKLSKRDESILQFIEQYRELGYLPD
                     AMFNFIALLGWSPVGEDEIFEHQELIKMFDPKRLSKSPAAFDAKKLQWVNNHYIKAMD
                     LDAFTDMCLPYLIADGRVAENPDEKTIEWVKKIVSLYQPQMSYAAEIVDLSTLFFNEH
                     PVLNEAAKEVLAGETVPTVLHAFKAQLEQMEVVDAPTVKAAIKAVQKETGVKGKNLFM
                     PIRVAVSGQMHGPELPETIELLGREKSLAHLNQVLN"
     gene            complement(6712..7869)
                     /locus_tag="ACG8LA_002543"
     CDS             complement(6712..7869)
                     /locus_tag="ACG8LA_002543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIN/TRAM domain-containing protein"
                     /protein_id="HFQ0204814.1"
                     /translation="MQKRVITLLMIIVGASLGISFLPSAWQAIGQQSNGWLNNTFTNS
                     LLGALIFFLLSLLLAKHISAIIKQVEQKLSEVSLTYLLFGAIGAIIGLTLGVVISTPL
                     YNMEIPFVNSVLPILLMIILGYLGLRMGTTRIEEWKKVFGSRSKKIEQETASQVESQL
                     LERKSGENFHKYKILDTSVIIDGRIYDITKTGFLEGTLMIPNFVLYELQYIADSGDSL
                     KRVRGRRGLDILNALQKEEGISVEMYDGDFEDISEVDSKLIKLAKLLDGVIVTNDYNL
                     NKVSEFQNVPVLNINALANAVKPVVIPGETMNVLVVKAGTERQQGVAYLDDGTMVVVE
                     DGQHYMNERIEVVVTSALQTAAGRMIFAKPAHAGRGIDNKKETEKKTKQSK"
     gene            complement(7903..9273)
                     /gene="radA"
                     /locus_tag="ACG8LA_002544"
     CDS             complement(7903..9273)
                     /gene="radA"
                     /locus_tag="ACG8LA_002544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HFQ0204815.1"
                     /translation="MAKKSKVQFVCQNCGYVSPKFLGRCPNCGKWNTMVEEIEQDTTD
                     RRTRTSLTGEKAKPTKIADVVPKKEPRIKTKLEELNRVLGGGVVPGSMVLIGGDPGIG
                     KSTLLLQVSQQLAAIGGKVLYVSGEESAEQIKLRAERLGSINTEFYLYAETDMNEISR
                     AIEHISPDYVIIDSIQTMTQPDITSVAGSVSQVRETTAELLKIAKTNGIAIFIVGHVT
                     KEGSIAGPRMLEHMVDTVLYFEGEQHHSFRILRAVKNRFGSTNEIGIFEMHEHGLEEV
                     ANPSQIFLEERLDGATGSAIVVAMEGTRPILVEIQALVTPTMFGNAKRTTTGLDFNRV
                     SLIMAVLEKRAGLLLQNQDAYLKAAGGVKLNEPAIDLAIAVSIASSYKEKGTQPTECF
                     IGEIGLTGEIRRVSHIEQRVKEVQKLGFTKVYLPKNNLGNWEAPKGIEIVGVATLAET
                     LKRVFR"
     gene            complement(9336..9863)
                     /locus_tag="ACG8LA_002545"
     CDS             complement(9336..9863)
                     /locus_tag="ACG8LA_002545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HFQ0204816.1"
                     /translation="MRKRGFEVISKYKDQNINLPQRATHHAAGYDFEAAEEVVIPSIW
                     KAGWKKGLETVADGLKKDVSENEKQLKPTLVPTGIKAYMGEDEFLQLANRSSNPLKRF
                     LVLTNGVGVIDSDYYNNEANEGHIMFQFTNFGFKDVVIKKGERIGQGIFLPFLKADQD
                     QTTAQRQGGFGSSSK"
BASE COUNT         2508 a         2214 c         1784 g         3367 t
ORIGIN      
        1 aatctcaggc tcgtttgctt tttaaactgc ttcagttaaa aattcgatct caactgtccg
       61 agtaagtaca tctgaatagc tgtaagatac tcgttcaaaa gaattttctt caggatccaa
      121 atcaacaacg aatactgaag gataggtttc tgttaaaacg ccgcggcgtt ctgtttgacg
      181 ctttcttcct gtctgagcaa ccaacatgat tgggctgccg atacgacctt ctaaatcttt
      241 cttgattgaa gctaaagttg ttggcataca gttcacctct actatcaact ataccacata
      301 tttttaaaat tttcaagttt accataaaaa aaaagaaatg caataaaaat aaataagaag
      361 ctcattaaga tttttctaaa ttattcctca ttataaaatt tcaagtgttt ttttattttg
      421 agttttactc tcccgtaagc gctcattact tgcttgtgat ccattgctaa acattcagcc
      481 atgtctacaa aatcaacgcc ttgcatataa taatgaaaaa ttttagcttc tatttttgaa
      541 aactggattt cgcaattttc gattgcttct tttaataaaa gatgctgaat cgctaaaggt
      601 tcttgcaatg tgatctctgc taaaaagtct ggtccttctg tctctatttt ttggtcgatt
      661 gagacttcat ctttttgatc acgacgcttc agcgcgttct gcttcctcaa cagagaatag
      721 atttgattgc ttataatgct tttataataa cttccaaagc taacaccttt gcttttttcg
      781 taagttctca atgcctgata taaagcgatc cttgcttctt gttcccaatc ctcagaaaca
      841 taatttctta aataataggt gtttttcaaa cgtagtaaaa gtggaaaata tttttgatac
      901 agggcagcaa atgcttcttc gtcaccatta cgtgcagcgc gcaataactc ctcagacata
      961 aaataattcc tccataaatt cgtttatgga ggaatcttat catcaatgat tcatcgaact
     1021 gattagaacg atatgttatt tattttttct cattaaatcg tccaattttt gggacaattt
     1081 ttttaactgc tcttcattcc atggagaatt acgtcggaaa tcaataaaat gcatatcttt
     1141 attttcttgg gctattgttt tttccgtttt ttttatcgtc ttatataatt cataagcaga
     1201 agttcgtaat gctccttggg aaaagatcat ccactgttct gctaaatcgc ttgtcgccac
     1261 tgtcacttgt gtcaaacggt cattcagctg accagcgatt ctctcgatat aactgtcagc
     1321 cgtttcgtct tctttcgtaa aaacaacatc caactggtat ttcttataat tttgttggat
     1381 gcccggaact agttgggcat cgaagacaac gatgacttcc attccttcat atttcgcata
     1441 atttgataaa cgatgtaaaa gagcttctct tgcatccgcc attttgtcct gctttttaag
     1501 ctggacaagt tccggccacg aaccaatcat gttgtagccg tctacaatca acagctgttt
     1561 tttcatggtc tactccccct gacgttggga aaaagcctga tacataagca aaccagcagc
     1621 aacactggca tttaagctct ggacgtgccc ggtcatcggg atcgtcagca attcatccat
     1681 ttcttttttc aatcctggac tcattccttt gccttcatta ccaatgacta aagcaattga
     1741 tcctttggca ttccattttt ggaagtttgt gccggtcata tctgtgccaa atacccaaaa
     1801 tcctgtttct ttgagctgtt gcacagcttg taccaaattc gtcacgcgtg caacagggac
     1861 atgttcgact gccccagtgg aagtctttgt tacgataggt gtgattccaa ctgctcggtg
     1921 ttttggtatg atcacaccat cgacgccact tgcgtctgct gtccgtaaaa tcgacccaaa
     1981 attgtgtgga tcttcgatgc tatccaaaat caaaaagaag gggtcttctt ttttctcttt
     2041 tgttcgttca atcagttggt caagggataa atattcataa ggtgtaatcg caagaacgac
     2101 tccttgatgc acgccgtgat cgctcaaagt ttctaatttt tgtttaggaa cccatttgac
     2161 tggcacagct tgttcacgtg cgatttcttt cagttcttct actttttctc ctcgtgaatc
     2221 ttcttgaaga aagagtttat tccctcgccc ttgttgtagc gcttctactg cggcatggtg
     2281 cccaaagacg aaattatctt ctaatgcttc ttcattttga tcagaaactg actgatttcg
     2341 tccagtttgc tttttatttg aatatctatt ttgttttttg tcttcaaatc cacgtttcga
     2401 ttgatgtttg tttgttcttt ctttacccat ttttttcacc aactttctga atacaccagc
     2461 ggatcaattc ttccatccgc tcggtttgtt ttgtcaaatg cagatagccc atgagcgctt
     2521 cgaaccctgt tgcgacccga tacgtcgtaa catcagcatt ttttgcgctc gtatggcttt
     2581 tagcatttct tcctctgcga taataaagtt cttcttcttc tgtcaaaaga tgttcttcca
     2641 gcatttgctg aatcaaaaag gcttgtgcat tcgcagaaac ataattcgtt gccgcacgat
     2701 gcagcttatt gggttttgtt tctccttgat caatcaggtg gtcacgaaca tagatttcgt
     2761 aaatcgcatc tccaacataa gccaaggcta aaccgttcaa ttgtgtgtaa tctctcatgc
     2821 ttctcttctc catcgggttc cttgcggtgt atcttctaat aagatccctt tttctttcaa
     2881 caaatcacga atttcgtcgc ttcggacaaa atcacgattg cttcttgctt gatttcgttc
     2941 ttcgatcaat tgttcaatct cttcatctaa taactcttct gctgtaaata aaataccgaa
     3001 gatcgaaagc cattgcgaga ataaagcttc tccttgtgcc aagacagcgg cagaaacttt
     3061 cggctggtct agataagtgt tcagccactt agcaagctca tagaccactg tgatcccatt
     3121 tgctgcatta aaatcatcgt ccatttcttc gatgaatcgc tgttctaaat tttctaacaa
     3181 agcgatttta tccgcatcat ctgccaaatt ctctgaggca gtttcttggc ggaatttcaa
     3241 attgtcaaac gtattcttca gtcgttgtaa attggtggct gcttctttca tcgtcgtttc
     3301 actgtagcgg atcggacgac ggtattgtgt ggtcgccatg aagaaacgca agacttgtgg
     3361 atcaacgttt ttgatcattt catgtacagt gatgaaattc cctagagatt tactcatttt
     3421 ttcatcgtct tcgccaatcg ttacatagcc attgtgcatc cagtaattag cgaatttttt
     3481 ccctgttttc gcttcacttt gtgcgatttc attttcatga tgaggaaatt ctaaatcttg
     3541 cccgccacca tggatatcga tcgtttctcc taaatgtttt gttgccataa cggaacattc
     3601 aatatgccaa ccgggacgtc ctttgcccca tggtgaatcc caagaaatct cgccaggttt
     3661 tgcttgtttc cataaagcga aatctaatgg gtcttctttt tgctgctgtt cttcccctgt
     3721 acgctgactt gctccgactt ccagttcatc gatggattgg tcacttaatt tcccataatt
     3781 ttcaaattta cgggtacggt aatacacatc acctgaagat tcataagcat agcctttttc
     3841 aaccaacact tgaataaatg ctaaaatatc tggcatatga tccatgactc ttggatgcag
     3901 tgtagcaggc tcgacattca acgctttcgt atcttcttca aatgctcgga tgaaacgatc
     3961 agcaacttct ggtgctgtaa tacctaattc gtttgctgta cggatgattt tatcgtctac
     4021 atccgtgaaa ttcgatacga aatcgacttt atagcctcga tattcaaaat agcgtcgaat
     4081 tgtatcgaaa gcaatggtgc tacgagcatt tccgatatgg atataattat acacagtcgg
     4141 tccgcagaca tacataccga catgtccctt ttgtataggg atgaattctt ctttttttct
     4201 ggtcaatgta ttgtagattt ttatcattct gatctcctca ctttttctcc tttgattcga
     4261 acgacttttg ctggtactcc taccgctgta gcgtcgtctg gaacatcttt caacacaacg
     4321 gcacctgcac cgattttggc gttttttccg atcgttaccg gtcctaatat ctgcgcattc
     4381 gcagagagca tggctccttg tttaacagtt gggtgtcttt tacccgtttc ttttcctgtg
     4441 ccgcctaatg ttacgccatg gaataaaatc acatcgtcct cgatttctgc ggtttcgcca
     4501 atgacgattc ccattccatg gtcgatgaac acgccagttc caatcgttgc tcctggatgg
     4561 atctcaacac cagttaggaa acgccagaat tgagcattga tcttcgccaa taaaaagagc
     4621 cggtgctgat ataaaaaatg agagaaacga tgccaaaaca aggcatgaaa accagggtat
     4681 gtcaaaacga tctcagctgt cgaacgtgca gccggatcgt ttctctttgc tgcatcaatc
     4741 gctcgggtaa accaactcat gactttccac tcctttcgta agaattttat gtaggaaatc
     4801 atcttcttat aaagaaaaga agcgcctttt aaataagttt ccttatcaaa agacgctttc
     4861 cgcgtggttc cacttttctt cataatcaat gattatctct gacagctaac gcctgttata
     4921 cgttcttggc tactttgttt cctataaaac agtttttcct gttttctgtg tttcgccaag
     4981 accactccca gaggcatttc ggcaaccatt cattgatacc ttgcaccacc cggtatctct
     5041 cttgtaatga tcagctgctt acttttttct gttcatcgtg tttagttcag tacttgattt
     5101 aaatgtgcta atgatttttc acgaccaagc aattcgatcg tttcaggcaa ttctggacca
     5161 tgcatttgtc ctgatacagc tacacggatt ggcatgaaaa gattttttcc ttttacgcca
     5221 gtttcttttt gaacagcttt gatggcagct ttgacagttg gagcatctac tacttccatt
     5281 tgttctagct gtgctttgaa tgcgtggaga acagtaggaa ctgtttcacc agcaagtact
     5341 tcttttgctg cttcattcaa tacaggatgt tcattgaaaa atagcgtaga cagatcaacg
     5401 atttctgcag catagctcat ttgaggttga tacaggctaa cgatcttctt cacccattcg
     5461 attgtctttt catctgggtt ttctgctaca cgtccatcag cgattagata aggcagacac
     5521 atgtcagtaa atgcatctag atccattgct ttgatgtaat ggttgtttac ccattgcagt
     5581 tttttcgcat cgaaagctgc gggtgattta cttaggcgtt ttggatcgaa cattttgatc
     5641 aattcttggt gttcgaagat ttcgtcttcg cccacaggtg accagcccaa taatgcaata
     5701 aagttgaaca ttgcatctgg tagatagcct aattcgcgat attgttcgat aaattgcaag
     5761 attgattcgt cacgtttgct tagtttttta cctgtttcac tgttgatgat caatgtcata
     5821 tgtccgaagg ttggtggtgt ccagccaaat gcttcataga tcatcagttg ttttggtgta
     5881 ttggcaatat ggtcatctcc acgtaaaacg tgagtgattt tcatcaaatg atcatcgacc
     5941 gcaacagcaa aattataagt tggcatacca tcgcgttttt gtatgacaaa gtcgccaccg
     6001 atattatcgg attcgaacga aatagcgcct ttcaccatat ctgtaaatgc gtattctgta
     6061 ttgcgaggca cacggaaacg tacaacagat tctagacctt gtgcttcttt ttctgcttgt
     6121 tcttcaggtg tcaagttcgc acatgttcct gcgtaatgag gcatttctcc tcttgcgcgt
     6181 tgtgcttccc gttctgcttc taattcttct tctgtgcaat agcatttgta tgctcgattg
     6241 ctagcaagca gctgatcaat cagcggttga tagatttctt tacgttcaga ttgacggtaa
     6301 gggccgtatt ctccaggatt ttcaggagat tcatcccaat tcattcccaa ccaagcaagg
     6361 ttttccaact ggcttttttc gccatcttcg atattacgtt tttggtcagt atcctcaata
     6421 cgaataataa agtctccatc attgtggcgg gcaaacaaat aattgaataa tgcagttctt
     6481 gcatttccaa tatgcaggtg cccagttgga cttggtgcat agcgtacgcg tactttcgtc
     6541 attttcttcc tcttctttca aactagactt tgactaacag caaaaattcc gtcagttacg
     6601 gcttctcaaa tatcatttat ttaaagccac tcagcacaaa ttttaccttt tctaaggtaa
     6661 atagtaaagc caactggttg aatttcctta ccagttggct gaatttcttt tttattttga
     6721 ttgtttagtc tttttctctg tctctttttt attgtcgatt cctcgtcctg catgtgcagg
     6781 tttagcaaag atcatgcgtc cagcagctgt ttgaagggca cttgttacaa cgacttcgat
     6841 acgttcattc atgtaatgct gtccatcttc tacgacaacc atcgtgccgt catcaaggta
     6901 ggctactcct tgttggcgtt ctgtcccggc ttttactact agaacattca tcgtttcacc
     6961 agggatgacg actggtttta cggcatttgc caacgcattg atattaagaa caggtacatt
     7021 ttggaattca gagactttat tcaagttata gtcattggtt acaatgacac catctaaaag
     7081 cttagccaat ttgatcaatt tgctgtctac ttcactgata tcttcaaagt ctccatcgta
     7141 catttcgaca gatataccct cttctttttg caaggcattt aggatatcta atccgcgacg
     7201 accacgcaca cgtttcaaac tatcccctga gtccgcgatg tattgtagtt cgtaaagaac
     7261 aaaattaggg atcatcaagg ttccttctaa gaatccagtc tttgtaatat cataaatccg
     7321 accgtcaatg atcacgcttg tatccaagat tttatattta tggaaatttt ctcctgattt
     7381 tcgttctaac agttgactct caacttgact agctgtttct tgctcgattt ttttgcttcg
     7441 tgaaccaaaa actttcttcc attcttcgat tcgtgtcgtt cccattctca atcccagata
     7501 gcctaagatg atcatcagta aaatcggcaa tacactattg acgaatggaa tttccatatt
     7561 gtaaagaggg gtcgagatca caacacctaa agtcaatccg atgatcgcac cgatcgcacc
     7621 gaagagaaga taagtcaagc tgacctcact tagtttttgt tctacttgtt tgataatagc
     7681 tgagatatgt ttggccaaca gcaaagataa taaaaagaaa ataagtgcgc ctaacaggct
     7741 gttggtaaat gtattattca gccatccgtt tgactgttga ccgattgcct gccaagctga
     7801 gggtaaaaat gaaataccca agcttgcgcc gacaatgatc atcagcaaag taatgacacg
     7861 tttttgcatc gtttttcctc cgtttcgaca atcatttatt agttagcgga acacacgctt
     7921 caacgtttca gccaaagttg ctactccaac tatctcgatt ccttttggcg cttcccagtt
     7981 acctaagttg tttttaggta ggtatacttt tgtgaagccg agtttttgga cttctttgac
     8041 tcgttgttca atatgactga cacgtctgat ttctccagtc agtccaattt caccgatgaa
     8101 acattccgtt ggctgtgttc ctttttcttt atagcttgaa gcaatactga cagcgatagc
     8161 taaatcaatc gctggttcat ttaattttac cccacctgca gcttttaagt aagcatcttg
     8221 attctgaaga agcaacccag ctcttttttc cagcactgcc atgatcagag atacccgatt
     8281 gaaatcaaga cctgttgttg ttcgtttggc atttccgaac atagtaggtg tgactaatgc
     8341 ttggatctct accaaaattg gacgtgtccc ttccattgcc acaacgatag cagagccagt
     8401 tgcaccgtct aggcgttctt ctaagaaaat ctgtgaagga ttagcgactt cttccaatcc
     8461 atgctcatgc atttcaaaaa tcccaatctc attcgttgag ccaaatcggt tttttactgc
     8521 tcgcaaaatc cgaaaactat gatgttgttc accttcaaaa tataacaccg tatccaccat
     8581 atgttctaac attcttgggc cggcgatcga gccttctttg gtaacatgac cgacgataaa
     8641 aatggctatc ccatttgttt tagcgatttt gagtagttct gcagtggttt ctcttacttg
     8701 gctgacactt cctgccacac ttgtgatgtc tggctgcgtc atcgtttgga tggaatcaat
     8761 gataacataa tcaggggaga tatgttcgat ggcacgactg atttcgttca tatctgtttc
     8821 agcgtataga taaaattctg tgttgatact tccgaggcgt tccgcgcgta attttatctg
     8881 ctctgcgctt tcttcgccgg atacatataa gacttttccg cctatggctg ctaattgctg
     8941 agaaacttgt aacagcaaag tggatttccc gatacctgga tcgccaccaa tcaagaccat
     9001 agaccctggc accacacctc cgcctaacac acggttcagt tcttctaatt ttgttttgat
     9061 ccgaggttct tttttaggga cgacgtctgc gatttttgtt ggttttgctt tttctcctgt
     9121 caaacttgtc cgagttctgc ggtccgttgt atcttgttcg atttcttcga ccatcgtatt
     9181 ccattttccg caatttgggc agcgtcccaa gaacttaggc gacacatacc cgcaattttg
     9241 gcaaacaaat tgtacttttg atttttttgc cattgtaccg cctcctttta tcctaatcat
     9301 gagacattaa atcaagctta agtatcttta acgttttatt tactggaaga accaaatccg
     9361 ccttgacgtt gagcagtcgt ttgatcttga tctgctttta aaaacggcaa aaagatccct
     9421 tggccgatac gctcgccttt tttgatcact acatccttga aaccaaagtt ggtgaattgg
     9481 aacatgatat ggccttcatt tgcctcatta ttgtaataat cactgtcaat cacacctact
     9541 ccgtttgtca acactaaaaa ccgcttcaac ggattgcttg aacggttagc aagctgcaaa
     9601 aattcatctt ctcccatgta agctttgatt ccagtaggca cgagggttgg tttcaattgt
     9661 ttttcatttt ctgatacatc ttttttcaat ccatctgcga ctgtttccaa cccctttttc
     9721 cagcctgctt tccagatact tggaatcacg acctcttctg ctgcttcaaa atcatagcca
     9781 gcagcatgat gtgtagcgcg ctgcggtaga ttgatatttt gatctttata tttagaaata
     9841 acttcaaatc ctctttttct caccggtttt cct
//
LOCUS       DAZKKZ010000086         9850 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.088, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000086 DAZKKZ010000000
VERSION     DAZKKZ010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9850)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9850)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9850
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.088"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            205..684
                     /locus_tag="ACG8LA_002546"
     CDS             205..684
                     /locus_tag="ACG8LA_002546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6530 family protein"
                     /protein_id="HFQ0204817.1"
                     /translation="MEIPTNLKHKPVIVVEDYDKVDGRNALNMDAKGLSLGLAQWNDR
                     GKVDISGKVWRHTGEKWSRQSEELPITRILDLAILAAQGSLYFQDAYRYEKFYDPENP
                     VVDIIGLQGNRMTVEVDTKNPKIDEDIILYYDTLQKDGELIGERFRILKRLLDELGY"
     gene            717..2945
                     /locus_tag="ACG8LA_002547"
     CDS             717..2945
                     /locus_tag="ACG8LA_002547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFQ0204818.1"
                     /translation="MENFSLTENRTFSRLEKQMIWKKPKSHRTSAEEWRIASEIKGNW
                     QDPEMKISNVLLEGDAGSGKTQLAKALSADLQLPYTKVTCFADMDKSDVFGALLPVVD
                     SNKEQDQELLEAIYQTDTLEAVLTLIQNHYGIDPFSAKEKLAELVQRIEADYPDAIHY
                     SYYPSEIVRAIEKGYLLEIQEPTVIRDASVLVALNSALEPNGMLNLPTGIIRRHPDCV
                     IVITTNRNYQGNRPLNESLRDRMQHAEKMDLPALEVMAERAMAKTMIQKQELLLKMAE
                     IIRLLDETAKANAIKGVAGMRSYFYWANTYKQGQDLLQSIYPKVLYKLSTDSDELAIL
                     EQALSDSGLLLELQDILRKEKWGHPQSEHTKERTISAEEANERNITENAEEILRLDEK
                     KSLSAEEPNEGEEKQEETIEKNEIPPQMQKERSSDIEGKNQKEQQTGDDSQEMSASDM
                     EAHDKEIKKQLNKEARQIMKETIHEKEGLIVHRPAFQGKTPEARELHMQVMPIVESLS
                     RQILELLDNEQTETYQKGKYEGQRFNASKVAYGDLRNFDKKNPPHEQPSLAVAVRIDE
                     SGSMIRDDRIEAAKKAAIAIAEFSKKVDIPLLIYGDTADRSSREKTSLFSYKEFEDGF
                     QWLNEKLVTMKPRQNNRDGAALRLAAEKLNRQSATTKLLLNISDGQPKALPDYTGKKA
                     KEDIQSVLKEYERQGILFVSAAIGQDKEEIKSIYGESRFVDITDLNEFPKQMIQLIAR
                     YL"
     gene            3074..4717
                     /locus_tag="ACG8LA_002548"
     CDS             3074..4717
                     /locus_tag="ACG8LA_002548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HFQ0204819.1"
                     /translation="MIQEQKWWKEAVGYQIYPASFKDSNGDGQGDINGIREKLNYLKD
                     LGIGFIWINPIYQSPFVDNGYDVSDYQDIEERFGTMEDFDLLLKEAHELGIKVIMDLV
                     INHSSDQHQWFEESKKSKESPYRDYYIWVDGVDGKEPNNWTSIFGGSAWEYSHETGQY
                     YLHVFAKEQPDLNWESEKLKEELFNMIRWWLDKGIDGFRLDAISHVKKDEYSVKATEN
                     PFSPFQNVSGIEEHLTDLKHVFEEYDIMTVGEASGVTAEEGPQWVGKDGYFDMIFEFD
                     HIHIWQQEKEGQLDVLKLKHALSAWQTSLDGIGWNALYMENHDVPRAVSVFGDTRPDF
                     WAMSAKAIAMMYFFLQGTPFIYQGQEIGMTNMPFESIDQVDAVDSKRLYKRLLAEGKT
                     REEALDIIRETTRDNSRTPMQWTSEQYAGFSTHEPWLITNPNTKTINVEQQEYEPESV
                     LQFYKNMIRIRQTNKGLIYGSYKEYLHEHPQLYVYERYLEDEQYLIMVNLTESLADYE
                     LPKEADQSWTLLLSNSSSGEFEAKGILAPYEARLYKTNK"
     gene            complement(4790..5335)
                     /locus_tag="ACG8LA_002549"
     CDS             complement(4790..5335)
                     /locus_tag="ACG8LA_002549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HFQ0204820.1"
                     /translation="MKLSEKELKDQLTEIVNDILAEAHLKKGDLFVLGCSTSEVVGGH
                     IGKNSSAEVGQWIIRTLKELLDPKEIALAVQGCEHLNRALVVERTVAEAKNFEIVSVV
                     PALHAGGACSVAAFDQFNDPVEVEHVVGQAGIDIGDTSIGMHIKHVQVPVRPRLKTLG
                     QAHVTALRSRPKYIGGPRANY"
     gene            complement(5358..5843)
                     /locus_tag="ACG8LA_002550"
     CDS             complement(5358..5843)
                     /locus_tag="ACG8LA_002550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HFQ0204821.1"
                     /translation="MKTKQLTIYAMLIALTVALSLTILIPVPATNGFVTLCEAGIYTA
                     AFLYGPTGGLVVGASSGLLIDLISGYPQWAVFSLVIHGLQGYVAGSFSKSSTRMWGLG
                     LLLGSLVMIIGYGIAGWILYDWPAGVASIPGNIFQNLIGMGLAFPITASLQRIQARKQ
                     Y"
     gene            complement(5833..6645)
                     /locus_tag="ACG8LA_002551"
     CDS             complement(5833..6645)
                     /locus_tag="ACG8LA_002551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylpyrimidine/phosphomethylpyrimidine
                     kinase"
                     /protein_id="HFQ0204822.1"
                     /translation="MKRILTIGGSDPFAGGGIQTDLKTFENFGLFGLSALTSIGALDI
                     NERFMLESISLELLKRQLVSIDKMTSLDGIKIGLLNSSEAIMVVRDFIKTKQNIPIIL
                     DPVLAFKETEAVINQLYISQLIEELFPLVTMITPNLAEAALLSGQALPSSLTEMIHLA
                     KELTASGTKNIVIKGGTRMAGDEAVDLLYSIDHYEVFSHKKIDTTTVNGAGCAFSSAI
                     TANLVLGADFTKAVAESKKFVAHCISNGVLMNDHTGSVWSGGIQKGGMRNEN"
     gene            complement(6784..8316)
                     /locus_tag="ACG8LA_002552"
     CDS             complement(6784..8316)
                     /locus_tag="ACG8LA_002552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HFQ0204823.1"
                     /translation="MMETITYSPLNLFTNFQEAAANFSETPIIFDEPLSAFPELGLET
                     TYKKCCESVLKRAYQLAHLGVKSGDKVIIYKSSAFDTYLLAVSVSYLGAVPVMTSYHL
                     PTTTMEVFIDRLEDPFILFDDETKKRVREISNGTKSKQIPILYLMEQPALSVSQSFLD
                     KNEISYMTHTSGTTGIPKLICHSAHSMGWRTKWQKTVFTKISEKKLIAFHISPVHSRF
                     NIGISSLMSMGFPMMPLANAQSSKVVHMLEAHRPIALETHPNNFVQWRFTAKEHPEAF
                     SGIRYYHSTFDAINNQTMKTFLRTSMAQDAVFLQVYGQSECGPMILKAHTLESLKTSD
                     ARDMGVGLEDMTSARITDSVGNVLPENTDGHIQLLSKGRALTYYKEDARFQENVYGDW
                     WDSGDYGFMDKHGHLFLKDRQVDLIETINSTLAIEDFLLDSLDFLAEVVIVRDKNHSP
                     QPIIALAPDKEMDWNRWWEQVHELPRLNVPIIRDFDAIPRTATMKVQRLQIEKELKSQ
                     KS"
     gene            complement(8425..9456)
                     /locus_tag="ACG8LA_002553"
     CDS             complement(8425..9456)
                     /locus_tag="ACG8LA_002553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFQ0204824.1"
                     /translation="MDSKTRKQLQEKLKQRTHLLPSVFQQFLEENRSSLSLGSRYEYA
                     KDFHLFTDYLRKVFSEEVDDQLIIHLEKQDYQNFLAKIYRHTRSFQTTANQETEQLFE
                     NSYYGISRKQYSLNHFLRFLYQKGLIEEEISLLGTSLPETTKAAPRYIDAELFKDFEH
                     LFIPIEGFQTSREASFEEKNRPRNLAITAILLYCGLKIHEVVELKRKDVSLTKQILNL
                     NRKENRLNKVPIPKEAMPFLENYFKLTAQNTDENSFVFRSSHDQQISPRTIRQILSKI
                     TVYKNVSPELCRKTYRYYAELYLDDADAVNYLCGNRYLSSHSFQDIWEKMVDFSYHEL
                     AAFVRVSSI"
BASE COUNT         3275 a         1830 c         1898 g         2847 t
ORIGIN      
        1 aaatattcca acatcatctt ggactttcta catgttacta atgagcgtgt aaaagaacga
       61 gatggtgttt ttatttctat caatgaagct ctttttcttt gcaatcctca cttcaatcct
      121 ctataatgtc gcatatagtt tagtaaatga gtaaactact aatttactta tttactaaaa
      181 ataaaaggat gaggagttaa aataatggaa ataccaacaa atttaaaaca taaaccagta
      241 atcgttgtag aagactatga taaagttgat ggaagaaatg cattaaatat ggatgcaaaa
      301 gggctttcac tgggccttgc tcagtggaat gatcgtggaa aagtcgatat ctcaggcaag
      361 gtatggcgac atactggaga aaaatggtca cgacagtcgg aagaattacc aatcacacgt
      421 attttagatt tagcgatctt agctgcgcaa ggaagtttat acttccaaga tgcttatcgt
      481 tatgaaaaat tttatgatcc agaaaatcca gtcgtagaca tcattggatt acaagggaac
      541 cgaatgacgg tagaagtaga taccaaaaat ccaaagatcg atgaagacat cattttgtat
      601 tacgatacac tacaaaaaga cggagaactg attggggaac gattccgtat tttaaaacgt
      661 cttttagatg agctaggata ttaatagaca gagatgatca aaaggggaag agaagcatgg
      721 agaatttctc actaacagaa aaccgaacct tttcacggct agaaaagcaa atgatctgga
      781 agaaaccgaa aagccatcgg acaagtgcag aagaatggcg gatcgcctcc gaaatcaaag
      841 ggaattggca agatcctgaa atgaaaatca gtaacgtact tttggaagga gatgccgggt
      901 cggggaagac acaattagcc aaagcactat ctgctgatct gcaacttccc tatacaaaag
      961 tgacctgttt tgcagatatg gacaaatcag atgttttcgg agccttatta cctgtagtag
     1021 attctaataa ggaacaagac caagaattac tagaagctat ttaccaaaca gatacacttg
     1081 aagctgtact gacactgatc cagaaccatt acggcattga tcctttttct gctaaagaaa
     1141 aattagcaga gctagttcaa aggatcgaag ctgattatcc agatgcaatc cattacagct
     1201 attacccttc tgaaatcgtt cgagcgattg aaaaaggcta tttattagag attcaagagc
     1261 cgactgtcat ccgagatgcc tctgttcttg tggcacttaa ctcagcgctc gaaccaaatg
     1321 ggatgttgaa tttaccgaca ggaatcattc gtcgccatcc agattgcgtc attgtgatca
     1381 ctacaaatcg aaattaccaa ggaaatcgcc cattaaatga atctttaaga gatcggatgc
     1441 aacatgcgga aaaaatggat cttcctgcct tagaagtcat ggcagaacgt gcgatggcga
     1501 aaactatgat ccaaaaacaa gaacttctct taaagatggc agagattatc cgtttgttgg
     1561 atgaaactgc aaaagctaac gccatcaaag gtgtagcagg aatgcgttct tatttttatt
     1621 gggcaaatac ctataagcaa ggacaagatt tactccagtc gatttatcca aaagttttgt
     1681 ataaattatc cactgattca gatgaattgg caattcttga acaagctttg tctgacagtg
     1741 gattgctact ggaacttcag gacatattga gaaaagaaaa atggggtcat cctcaatctg
     1801 agcatacaaa agaaagaacc attagcgccg aagaagcaaa tgaacgaaac atcactgaaa
     1861 atgctgaaga aattctgcgc ttagatgaaa agaaatcgtt gtctgctgaa gaaccaaatg
     1921 agggagaaga gaaacaagaa gaaacaatag aaaaaaacga gattcctcct caaatgcaaa
     1981 aagaacgcag tagcgatatc gaaggaaaaa atcaaaaaga acaacaaaca ggagatgatt
     2041 ctcaagaaat gtctgcttct gacatggaag cacatgataa ggaaatcaag aagcaactga
     2101 ataaagaagc gcgacaaatc atgaaggaaa cgattcatga aaaagaaggt ctcatcgttc
     2161 accgaccagc tttccaagga aaaacgccgg aagcacgtga gctacacatg caagtaatgc
     2221 caatagtaga atcacttagc cggcaaattt tagagttact ggataatgaa caaacagaga
     2281 cgtaccaaaa aggaaaatac gaaggtcagc ggttcaatgc aagcaaagta gcatatggtg
     2341 atttgagaaa ttttgacaaa aagaacccgc cacatgagca accttcttta gcggtagctg
     2401 tacggatcga tgaatctggg tcaatgatac gggatgatcg gatcgaagcg gcaaaaaaag
     2461 cagcgattgc cattgccgaa ttttctaaga aagtcgatat cccattgttg atttacggag
     2521 atacagcaga ccgttcgtca agagaaaaga cttctttgtt ttcttataaa gaatttgaag
     2581 acggatttca atggttaaat gaaaaattag tcactatgaa accaaggcaa aacaatcgtg
     2641 atggtgctgc acttcgttta gcagcagaaa aattaaacag acaatccgca acaaccaaac
     2701 tgttgcttaa tattagtgac ggtcagccaa aagcgttgcc ggattataca ggcaaaaaag
     2761 caaaagaaga tatccagtct gttttgaaag aatatgaacg tcaaggaatc ctatttgtct
     2821 ccgcagctat tggccaagac aaagaagaaa tcaagtcgat ctacggtgaa agtcgttttg
     2881 tagatattac tgacttgaat gaatttccca agcaaatgat tcaactgatt gcccgctatc
     2941 tatgataaaa taaagctcag cgaacgcact tagcagattc gttgagcttt tcgtttctag
     3001 ttaccggtaa caaggatact tctaaaatag aatcggttat aatcaagagg gaccgttaaa
     3061 ggagtgaaac gatatgatac aagaacaaaa atggtggaaa gaagcagtag gctatcaaat
     3121 ctatcctgct agtttcaaag atagcaatgg cgatggtcaa ggagacatca atgggatccg
     3181 tgaaaaactt aattatttga aagatcttgg tatcggcttt atctggatca atccgatcta
     3241 tcaatctcca tttgtcgata atggttatga cgtaagtgac tatcaagata tagaagagag
     3301 attcggaacg atggaagatt ttgatttatt gctaaaagaa gcacatgaat tagggatcaa
     3361 agtgattatg gatcttgtca tcaaccatag ttcggatcag catcaatggt ttgaagaatc
     3421 gaaaaaatct aaagaaagcc cgtatcgcga ttattacatt tgggtcgacg gggtagatgg
     3481 caaagaaccg aataattgga catcgatttt cggcggttct gcttgggagt attctcatga
     3541 aactggacag tattatctgc atgtttttgc aaaagaacaa ccagacttaa attgggaaag
     3601 cgagaaattg aaagaagaac tattcaatat gatccgatgg tggttggata aagggataga
     3661 tggatttcgt ttagatgcga tttctcatgt aaaaaaagat gaatattcag taaaagccac
     3721 agagaaccct ttctcaccct ttcaaaatgt ctcaggaatc gaagaacatt tgaccgattt
     3781 gaaacatgtt tttgaagagt acgatatcat gactgtcgga gaagcaagtg gtgtcactgc
     3841 agaagaagga ccacaatggg tagggaaaga cggttatttc gatatgatat tcgaatttga
     3901 tcatatccat atctggcagc aagaaaaaga agggcaatta gatgtcctta aattgaaaca
     3961 tgcattaagc gcttggcaaa cttcattgga tggtatcgga tggaacgctt tatatatgga
     4021 aaaccatgat gttcctcgtg ccgtttcagt gtttggagat actcgtcccg atttttgggc
     4081 tatgtctgca aaagcaatcg ctatgatgta tttctttttg caaggtacgc catttattta
     4141 tcaaggacag gaaatcggaa tgacgaatat gccctttgaa tcgatcgatc aagttgatgc
     4201 agtagattcg aaaagacttt ataaaaggct gcttgcggaa ggtaagacaa gagaagaagc
     4261 attggatatc attcgtgaaa caacgagaga caacagcagg acacccatgc aatggacttc
     4321 ggaacaatat gctggttttt ctacacatga accttggctg atcactaatc caaataccaa
     4381 aacgatcaat gtagaacaac aagaatatga accagagtcg gtcctgcaat tctataagaa
     4441 catgatccgc attagacaaa ccaataaagg tctgatatac ggttcttata aagaatatct
     4501 tcatgaacat ccacaacttt atgtctatga aagatattta gaagatgaac aatatcttat
     4561 tatggtaaac ttaacagaat cacttgctga ctatgaactt ccaaaagaag cagatcagtc
     4621 ctggacatta ctcttgtcaa attcctctag cggagaattt gaagctaaag gcatactagc
     4681 accttatgaa gctcggttat ataaaacaaa caagtaaaac ttcctcgtta aagttcatta
     4741 gttggacttt gcgaggaagt ttttcagatt gctctgtcaa ttactcattt caataattcg
     4801 ctctaggacc accgatatat ttaggacgag agcgaagggc tgtcacgtga gcttgtccaa
     4861 gggttttcaa acgaggtctg acaggtactt ggacatgctt gatatgcata ccgattgatg
     4921 tgtcaccgat atcgataccg gcttgtccaa ctacgtgttc cacttcgaca ggatcattga
     4981 actggtcaaa agcagcaaca gaacaagcac ctccagcatg tagtgcagga acaacagaga
     5041 caatttcgaa attttttgct tctgccactg ttcgttctac tactaatgct cggttcaaat
     5101 gttcacaacc ttggacagct agcgcaattt ctttaggatc caacaactct tttaacgtac
     5161 ggatgatcca ttgaccaact tccgcactgg aattttttcc aatatgtcct ccaacgactt
     5221 cgcttgtgct gcatcctaaa acaaaaagat cacctttttt caagtgtgcc tcagccaata
     5281 tgtcattaac tatttcagtc aattggtctt ttaattcttt ttctgacaac ttcattttct
     5341 aaaaccttct ttttcaatta atattgcttc cgtgcttgaa tacgttgaag acttgcagtt
     5401 ataggaaagg caagtcccat tccaatcaga ttttggaaga tgtttcctgg tatagaagcc
     5461 actccagccg gccaatcata taaaatccaa ccggcgatac catagccgat gatcataact
     5521 aagcttccta ataaaagccc taatccccac atacgagtag aagatttgct gaaagaacca
     5581 gcaacatatc cttgtaaccc gtggatcact aatgaaaaaa ctgcccactg cggatatcct
     5641 gaaatcaaat cgatcaatag accactggaa gcaccaacaa ctaatccacc cgttggacca
     5701 taaagaaaag cagcggtata gatcccggcc tcgcataatg tcacaaatcc attcgtagcc
     5761 ggtacaggga tcaaaattgt taatgaaagg gcaactgtca acgcaatcag catagcatag
     5821 atcgttaatt gcttagtttt catttctcat tcctcctttt tgaataccgc cagaccagac
     5881 acttccggta tgatcgttca tcagcacgcc attagaaata caatgggcaa caaatttttt
     5941 actttctgct actgctttgg taaaatctgc ccctaacaca agattcgctg ttattgcaga
     6001 agaaaaggca caaccggccc cgtttactgt tgtagtgtcg atttttttat gagaaaatac
     6061 ctcataatga tcaattgaat agagaagatc cacagcttca tctccagcca tccttgtgcc
     6121 gcctttgatc acaatgtttt ttgttcctga agcagtgagt tctttagcga gatggatcat
     6181 ttctgttaac gaagagggaa gagcttgacc agaaagtaaa gcagcttctg ccaaattagg
     6241 cgtaatcatc gtaacaagtg gaaaaagttc ttcgatgagc tgcgaaatat acaattgatt
     6301 gatcacagct tcagtttctt tgaatgccaa aacagggtct aaaatgattg ggatattttg
     6361 ttttgttttt atgaagtctc gaacaaccat gattgcttca cttgaattca ataacccaat
     6421 tttgatacca tctaatgaag tcattttatc aatcgaaact aactgtcgtt taagcaattc
     6481 caaagatata gattccagca taaatcgctc attaatatct agtgccccta tagaagtcaa
     6541 ggcgcttagt ccgaatagac caaaattctc aaaagttttt aaatctgttt ggattcctcc
     6601 accagcaaat ggatcagaac cgccaattgt caagattctt ttcataacat tttcctccat
     6661 gaataagagt ataacgaaat tttcaaaaaa gaaaaacagc caattggcat atttttatct
     6721 catccaattt aaaaaaacaa aaagaaaaga aagaccaaaa tggatctttc tttccttaaa
     6781 tagttaggac ttttgtgatt ttaattcttt ctcgatttga agccgttgca ctttcattgt
     6841 agctgttcgc gggattgcat caaaatcacg gatgataggg acgttcaagc gaggaagttc
     6901 atggacttgc tcccaccatc gattccaatc catttcttta tcaggagcta aagcaataat
     6961 cggttgtgga gaatgatttt tatcccttac aatcactact tctgccaaaa aatctaacga
     7021 atctaataaa aagtcttcaa tagctaatgt actattgatc gtttcgatca aatccacttg
     7081 ccgatctttc aaaaataggt ggccatgctt atccataaaa ccgtaatctc cgctatccca
     7141 ccaatcgcca taaacatttt cctggaaccg tgcatcttcc ttgtaataag tcaaagcccg
     7201 tcctttagac agtaattgta tatgaccatc tgtgttttca ggtaggacat tcccaactga
     7261 atctgtaatc cgagcgcttg tcatgtcttc cagtccaacg cccatatctc ttgcatcact
     7321 tgttttcaaa ctctctagtg tatgagcctt aagaatcatt ggtccgcatt cactttggcc
     7381 atatacttga agaaataccg catcctgtgc catcgacgtt cgcaaaaatg tcttcattgt
     7441 ctggttgttt atagcatcaa aagtggagtg atagtatcgg atacccgaaa aagcttctgg
     7501 atgctcctta gcagtaaaac gccactgaac aaagttattc ggatgggtct ctagtgcaat
     7561 tggccggtga gcttccaaca tatgaacaac ttttgaactt tgtgcgtttg ctaaaggcat
     7621 cataggaaat cccatggaca tcaaagaaga gataccaata ttgaatctgg aatgcactgg
     7681 agagatgtga aaagcgatta atttcttttc cgaaattttt gtgaaaactg ttttttgcca
     7741 tttcgtccgc catcccatag aatgagcaga atgacaaata agtttaggga taccagttgt
     7801 accagaagta tgggtcatat aagaaatttc atttttgtct aaaaatgatt gagaaacaga
     7861 caaagcaggt tgttccatta aataaagaat aggaatctgt tttgattttg ttccatttga
     7921 aatttctctc actcgctttt ttgtctcatc atcaaataaa atgaaagggt cttctaaacg
     7981 atcgataaat acttccattg ttgttgttgg tagatgataa gaagtcatga caggcactgc
     8041 accaaggtaa gacacagaaa cagctagaag gtatgtgtca aaagcggaac tcttataaat
     8101 aataactttg tctccggatt tcactccaag atgagccaat tgataagccc gtttcaacac
     8161 actttcgcag cattttttgt aagttgtttc aagtcctaat tctgggaaag ctgaaagtgg
     8221 ctcatcaaag ataatcgggg tctcggaaaa gttagctgca gcttcttgaa aattcgtaaa
     8281 taagttcaaa ggggaatacg ttatggtctc catcattcac actccattat cttttgttaa
     8341 gtaatataca aattcaagat aatcgtaaca taatccttta tataataaca tagtttattg
     8401 tgaaaaaaag atcatacatt tgttttatat ggaagaaacc cgaacgaatg ccgctaattc
     8461 gtgataagaa aaatcaacca tcttttccca gatatcttga aaagaatggg atgagaggta
     8521 tcgattacca cataaataat ttaccgcgtc agcatcatct aaatatagtt ctgcataata
     8581 acgatatgtt tttctgcata gttctggcga tacgttttta tatactgtaa ttttgctcaa
     8641 aatttggcga atagtccgag gagaaatttg ctgatcatgt gaggaacgaa aaacaaaaga
     8701 attttcgtcc gtattttgtg ctgttaactt aaaatagttc tccagaaatg gcatcgcttc
     8761 ttttggtatt ggtactttat tcagtctgtt ttcttttcta ttcagattaa gaatctgctt
     8821 ggtcaaagat acatctttac gtttaagttc tactacttca tggatcttta atccgcaata
     8881 cagaagaatg gcagtaattg caaggttcct cggtctattc ttttcttcaa agctagcttc
     8941 tctgcttgtt tgaaagcctt caatcgggat aaacaaatgc tcaaaatctt tgaaaagttc
     9001 tgcatcgata tatcgcggag ctgctttggt tgtttccggt aaacttgtac ccaaaagaga
     9061 aatctcttct tcaatcagtc ctttttgata caaaaatcgt aaaaaatgat ttaatgaata
     9121 ttgcttcctt gaaatcccgt aatagctatt ttcaaacaat tgctccgttt cttggttcgc
     9181 tgtagtttgg aacgaacgag tatgtcgata gattttagct aagaaattct gataatcttg
     9241 tttttctaaa tggataatca gctgatcatc cacttcttca gaaaatactt ttctcaaata
     9301 atcagtaaac agatgaaaat cttttgcgta ttcatagcga ctgcctaatg aaagggaaga
     9361 acgattttct tctaaaaact gttgaaagac ggaagggagc aagtgtgtac gttgctttaa
     9421 cttttcttgc agttgttttc tagttttgct gtccattaca aattccctcc aatagtgttc
     9481 attttctata ttttaccgca tttcatcaaa tgaagataga cagtttgtct tgatcttagg
     9541 aagcaaattt ttaactaagt actagctaaa agatatgaag taagaagata catttttagt
     9601 tattttatta gtgcagtcat tcttttgatc ttttaattga tttatcctct ttttagctat
     9661 gtggttactt catgagcaat gaaatggatt tggttcgttc taatggcagg aggctctttc
     9721 ttttatttcc gaaaaattag aaaacatttt ttcagaatcg attggctctc catttattca
     9781 ataatggttt gtctaacgat attgttggga taattcttaa agaagtatta gaaatagttg
     9841 gtacttcatt
//
LOCUS       DAZKKZ010000087         9663 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.089, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000087 DAZKKZ010000000
VERSION     DAZKKZ010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9663)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9663)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9663
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.089"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..630)
                     /locus_tag="ACG8LA_002554"
     CDS             complement(<1..630)
                     /locus_tag="ACG8LA_002554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HFQ0204825.1"
                     /translation="MEIKVLFENSRINLNFKSGHGLSLLINYSGKKYLFDAGANKKLV
                     YNATKMGETLNDLEAVIISHGHSDHTGGLRYLKSGNAPIYTAEGVTLPHYLKILTTFL
                     YVGIPKNEILKMHENLHTIKTKTELAPSFHIIPLGKANSTTKNLYKKMDDKFVYDDFS
                     DELLVVIEQEDGLIVFTGCSHHGIIDMMEIALETFPTKPIKYLIGGFHMI"
     gene            973..1389
                     /locus_tag="ACG8LA_002555"
     CDS             973..1389
                     /locus_tag="ACG8LA_002555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFQ0204826.1"
                     /translation="MATIILASHGEFAQGLKQTATMIIGDSVPIHALSAFRDEDESIL
                     VQIKKLLATIDIEETYILTDILGGSVNNDMLTIIKEYEGLQLITGMNLPLVISIATYN
                     GKIGESELEKLIKESQQSVIDCRKLLVEQLTGGDDL"
     gene            1386..1856
                     /locus_tag="ACG8LA_002556"
     CDS             1386..1856
                     /locus_tag="ACG8LA_002556"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFQ0204827.1"
                     /translation="MIKLVRIDHRLLHGQVVFSWSKSLNINRIIIANKEAANDEFKKM
                     SLNLSKPTGIKLTIFSVEQLLEKMPKIETLNENIMLIFGNTKEIRQFCEAYPKVQEIN
                     YGGIIKKEGSKQFSNAIFLNESEQEDAKKLKALGIKQFIQQVPTSKKEDLNTML"
     gene            1870..2643
                     /locus_tag="ACG8LA_002557"
     CDS             1870..2643
                     /locus_tag="ACG8LA_002557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HFQ0204828.1"
                     /translation="MLVQSIGLGLIGVFCILDSRLLGRMNFERPLIVSTLVGLVLGDM
                     EKGLIVGASLELMSLGLVNIGAAAPPDMNMASIIATAFAILSNANAEAALTIAIPISV
                     LGQILGILMRTILSNLTHVADRFIEQGKFSQARRIHILYGSGLYALMYFIPIFLAIYF
                     GTNLVSQIVDAIPEWLTNGLTVASKILPAYGFALLLQTMLTKKMVPFLLLGFLITAYS
                     GLGIIGIAAFACIVAFVMVQVQGKNSNGNQNEPDPLDDL"
     gene            2657..3469
                     /locus_tag="ACG8LA_002558"
     CDS             2657..3469
                     /locus_tag="ACG8LA_002558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HFQ0204829.1"
                     /translation="MKEKDQNAWKYRQFLWRSWAIQASWNYERQMNMGFMYGIAPILD
                     NIYKNPEDEAMKKEAYERHMMYYNCTPQTSAFVLGLTASMEEQYYEDQENFNPESISA
                     VKTSLMGPLSGVGDSFFQGTIRVLAFGLGINLAQQGSILGPILAMLISFVPSFLVTYY
                     GGKIGYNMGNKYLSKLYQEGLMDKVMYVCSIVGLMVIGSMIASMIGITTPIQMGKAFV
                     LQDVLDSIMPQFLPLGLTFFMYWLLQKKVKTGWMLAICLVGGIIFSLLGILQ"
     gene            3523..4488
                     /locus_tag="ACG8LA_002559"
     CDS             3523..4488
                     /locus_tag="ACG8LA_002559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HFQ0204830.1"
                     /translation="MNSKEIVKEIVAKKEVKSIVFVGCGASKADLYPAKYFLDQNAKQ
                     LRISHYTASEFNYATPASVDESTVVISASLGGTTPETVEANAVAKEKGATVISLTRSI
                     DSPLTKDADYVIYHRFAENYAAKLEKTGYCLELAVELLHQVEGYDHYEAMQEGFATIY
                     DLAQKSAESARKDAKKFAERFKDEKVIYVMSSGATHEVAYSTSICLMMEMQWINSGTF
                     HSGEFFHGPFEIVDKDVPFILLMNDGKTRNIDARALTFLERFDTKTEVVDALDYGLSS
                     HIAKEVLDYFNPFVITAVFRVYAEELSEAREHPLTKRRYMWKLTY"
     gene            4604..7327
                     /locus_tag="ACG8LA_002560"
     CDS             4604..7327
                     /locus_tag="ACG8LA_002560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFQ0204831.1"
                     /translation="MQRLNDYLYQLTLLLKSTPSDNYSARSISQALQLNRSTISSYLN
                     EGVREGLFIKVKSYPVLFLHRTALEELHITLNNSEIESIESLLTISQKPALDQVIGSK
                     GSLKEAIDQIKTAVLYPGKGLPLLLIGASGSGKTFLANKIYEYAVEEKVIHTSAPFID
                     YNCAQYVSNPELLSSALFGYTKGAFTGASQEHTGLLEKADGGVLFLDEVHRLSEEGQE
                     KLFTFMDTGEFSPMGDNSIRKKADVRLVFATTENIYTTFLPTFLRRLPVIVNLPRFQQ
                     RPSFERLSLIDEFFVSESKILAKELSVSDALIHFLMNSDFEGNVGNIKNIIKYACGNA
                     YIHQKSQQTIQVKLLDMPLEYSYKFKEQLNKPRKKRADRIYYPEETRQVQLERNNQLF
                     VQFFDQLLTGFSEVIENNKDIKLFLEEMVTKVTQVMDTLIFQEDYEKEQSLYAILNYH
                     IRQSIDFMRESYGFEQDGNRVVALANYLYVKDNQVIFENSLQEKKTKDQLNEFFANVL
                     ETPYWYAKKILSLLSECLDQPVYEEDIFFITLYFYSLNVTNVKTGIKSIVLAHGYSTA
                     SSMANVANRMLNKNVFQAYDMPLDITLEKIEAKLIQFLGDYRTDSGLILLVDMGSLNQ
                     LGGLLVNHLNGPLLIIDHINTPLLLEVGQQVLNNKSITEIGAEIETSLTFKKQLLLPK
                     KKKKKAIITCCYTGIGSATQIQEILTKCLKDAVRELVIIPYDYKKLLENKNFETPFQL
                     YDVIMIVGTEDPKINQIPYIGLDRLINGEAIGEFVHYLEKELTIEVNDLQKELIFNFS
                     ISKIVENLTILDPDKVLSFVQKAIKELSKLLNFDFSNNQLFLLYLHCSCMIERIVRKE
                     SVDEQEDIEEYMQANGEIMDKIHSAFFEIEREYTIEIPDLELRLLSDIVQG"
     gene            7340..7972
                     /locus_tag="ACG8LA_002561"
     CDS             7340..7972
                     /locus_tag="ACG8LA_002561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFQ0204832.1"
                     /translation="MTMGVIFDMDGVLIDSETFYFERRMNFFQELEIDPGSNQIDDYV
                     GKTEAAIWETLVPEDKSLREELYPKYVDYRKTHPIDFAKDLRKEVKPLLDFLKKRDIP
                     LALASSSPVVEIESMLIQCELTEYFSFVISGESLKQSKPHPEIYLKAKQQLDCDFFIA
                     VEDSTIGIKSAKAANIYTVALKQPMQIDQSEADIQIESLQELEQIVLEKG"
     gene            8871..>9663
                     /locus_tag="ACG8LA_002562"
     CDS             8871..>9663
                     /locus_tag="ACG8LA_002562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0204833.1"
                     /translation="MKNLQLKFIVDPSIVRWFRIINQFERNQLATKGELAKSNHVSER
                     TIQTDVNKMKDYFSESVQFVSTKSGYSFQKERPVLFLKQKEQLLENEILFELLGNVFY
                     GELEDMTELIDRFHLSEATFRRYLKQIQPVLEEYGLELSLYPLDLKGEEANIRKFFKD
                     FYYEGEMTPHTLVPPRDLHELVQATFYDKFEYFSIGTGTSPAEFYYSLYIAIERVRQG
                     KTIAIPQGLIERVIASENFRLMYSLKEAIQTNYQVALSEEEFCWLY"
BASE COUNT         3260 a         1475 c         1884 g         3044 t
ORIGIN      
        1 aatcatatgg aagccaccga ttaggtattt tatgggttta gtcggaaatg tttcaagagc
       61 aatttccatc atatcgataa tgccatgatg actacagcca gtaaagacaa tcagaccgtc
      121 ttcttgctca attacgacca ataattcatc tgaaaaatca tcataaacaa atttatcatc
      181 catctttttg tataaattct tggtggtcga gtttgctttg cctaggggga tgatatggaa
      241 gctcggagca agttctgttt tcgtttttat tgtatgtaaa ttctcatgca ttttaaggat
      301 ttcattttta ggaataccaa catacagaaa cgtggttaaa atctttaaat aatggggtaa
      361 agttacacct tcagctgtat aaataggggc gtttcctgat tttaaatatc ttaacccgcc
      421 ggtgtggtca gaatgaccgt gtgaaataat cactgcctcc agatcattca aagtttcccc
      481 cattttagtc gcattataga ctaatttttt attagcgcca gcatcgaaga gatatttctt
      541 ccctgagtag ttaattaaga gagataaccc atgtccactt ttaaagttca aatttattct
      601 tgagttttca aataaaacct tgatttccac tataacatct cctttcacat gaacgtgtat
      661 tcatatattg tagcacatta agttctattt tttgttgtaa ttaccgaaaa aaatattaat
      721 ggacgctttt tacgctttat ttcgtatgtg gaagaaaatt tcttaggatg tggcggggga
      781 ttggggcaaa gctaaattcc aattacagtg atcatttaat tagacacctt taaataccca
      841 cactttcatc aacactataa tttagggaaa gaaaagtgtt ggcatgatat agaaaaacct
      901 ttaattaaca gcgtttccta aaattggcac gcatcttgct tatagaaaag cgtaaggata
      961 ggaggaatga aaatggcaac tataattctt gccagccatg gggaatttgc tcaaggatta
     1021 aagcaaacag ctacaatgat tattggagat agtgtaccaa ttcatgcctt gtcagcattt
     1081 agagatgaag atgaatctat tttggtacaa ataaaaaaac ttttagccac aatagatata
     1141 gaagaaacct acattttaac tgatattcta ggtggtagtg tgaataatga tatgctcact
     1201 attattaaag agtatgaggg attgcaatta attactggaa tgaacttacc tttagttatt
     1261 tctattgcaa cctataatgg aaaaattggg gaaagtgagc tagaaaagct tattaaagag
     1321 agtcaacaat cagtgattga ttgtagaaaa ttattagtag aacaacttac tggaggagat
     1381 gacctatgat taagttagta cgtattgacc atcgtttgtt gcacggacag gtagtatttt
     1441 cttggagtaa atcattaaat atcaatcgta ttattattgc caataaagag gcagcgaatg
     1501 atgaattcaa aaaaatgtct ttgaatttat ctaaaccgac tggcattaaa ttaacaattt
     1561 tttcagttga acagttacta gaaaaaatgc ctaaaatcga aacacttaac gaaaatatca
     1621 tgcttatttt tggtaataca aaagaaattc gtcaattttg tgaagcctat cctaaagtac
     1681 aagaaatcaa ctatggaggg ataatcaaaa aagaaggttc caagcaattt agtaatgcca
     1741 ttttcttgaa tgaatctgag caagaagatg ccaaaaaatt aaaagctctt ggcattaaac
     1801 aatttattca acaggtacca acttctaaaa aagaagattt gaatacaatg ttataaagga
     1861 ggaatgaaaa tgctcgttca gtcaattggt ttagggttaa tcggtgtttt ttgtatttta
     1921 gactcaaggc ttttaggaag aatgaatttt gaacgaccgt tgattgtcag tacgcttgtt
     1981 ggtttggtac ttggagacat ggaaaaagga ttaattgttg gagcctcttt ggaattgatg
     2041 tccttaggat tagtaaatat cggagctgct gcaccacctg atatgaatat ggcatcaatt
     2101 attgctacag cctttgccat tttatcaaat gcgaatgcag aagcagcatt aacgattgcc
     2161 attccaattt cagtgttagg tcaaatacta ggtatcttaa tgcggacgat tttgtcaaat
     2221 ttgactcacg ttgcggatcg ctttatcgaa caagggaaat ttagccaagc aaggagaatt
     2281 catatacttt atggctcggg attatatgct ctcatgtatt ttattcctat ttttctagca
     2341 atttattttg gaacgaatct tgtttctcag attgttgatg cgattcctga gtggctaaca
     2401 aatggcttaa cggttgcaag taaaatttta ccagcatatg ggtttgcgtt gttattacaa
     2461 acgatgttaa cgaaaaaaat ggtgccattt ttattacttg gatttttaat tactgcttat
     2521 tctggattgg gaatcattgg tattgcagcc ttcgcatgta ttgttgcgtt tgtcatggtt
     2581 caagttcaag gtaaaaactc aaatggtaac caaaatgagc cagatccatt agatgactta
     2641 taaggaggta gattaagtga aagagaaaga tcaaaatgca tggaaatatc ggcagttctt
     2701 atggcgttca tgggcaattc aagcctcatg gaactatgaa cgacaaatga acatgggttt
     2761 tatgtacgga attgcaccaa ttctagataa catttacaag aatccagaag atgaagcaat
     2821 gaagaaagaa gcttacgagc ggcatatgat gtactacaac tgtacccctc aaacaagtgc
     2881 atttgtgtta gggttaactg cttctatgga ggagcaatac tacgaagacc aagaaaactt
     2941 taatccggaa tcaatcagtg cagtgaagac ttctctgatg ggaccgctat ctggtgttgg
     3001 tgattctttc tttcaaggaa cgattcgggt attagccttt ggactaggaa ttaatttagc
     3061 ccaacaaggt agtattttag gtccaattct agcaatgtta atttcctttg taccttcctt
     3121 tttagttact tactatggtg ggaaaattgg ctataacatg gggaataaat acttgtctaa
     3181 actgtatcaa gaaggtttga tggataaagt aatgtatgtt tgctccattg tggggttgat
     3241 ggtcattggt tcgatgattg ccagcatgat cgggattaca acaccaattc aaatgggtaa
     3301 agcttttgtc ttacaagatg tattagatag tattatgcca caatttttac cattaggatt
     3361 aaccttcttc atgtactggt tattgcagaa aaaggtcaaa acaggatgga tgttggcaat
     3421 ctgtttagtc ggaggaatta tttttagttt gttaggtatc ttacaataag ggaataacca
     3481 ataaatttgg ttgaataata taaataagga ggaattcaat tgatgaattc aaaagaaatt
     3541 gttaaagaaa tcgtagcgaa aaaagaggta aaatcaatcg tatttgttgg ctgtggcgct
     3601 tcaaaagcgg acctttatcc tgcaaagtat tttctagacc aaaatgcgaa gcagttacgg
     3661 attagtcatt acacagccag cgaatttaac tatgcaacac cagcatctgt agatgagtca
     3721 actgtcgtta tttcagcttc tttaggaggt acgactccag aaacagttga agctaacgca
     3781 gtagctaaag aaaaaggtgc tacagttatt agtctaacac gaagcattga ctcaccgtta
     3841 acaaaagatg cagattatgt aatttatcat cgatttgcag agaactatgc tgctaaatta
     3901 gaaaaaacag gctactgttt agaattggca gtagaacttt tacatcaagt agaaggttat
     3961 gaccattatg aagcaatgca agaaggattt gctactatct atgatcttgc ccaaaaaagt
     4021 gcagaatcag ctcgtaaaga tgcgaagaaa tttgctgaac gctttaaaga tgaaaaagtt
     4081 atttatgtaa tgagtagtgg tgctacacat gaagtagcat actcaacatc aatttgcttg
     4141 atgatggaaa tgcaatggat taattctggt accttccatt caggagaatt tttccacgga
     4201 ccattcgaaa ttgtggataa agacgtaccg tttatattat taatgaatga tggaaaaact
     4261 agaaatatag atgctcgagc attaactttc cttgaacgct ttgatacgaa aacagaagtt
     4321 gtagatgcct tggattatgg cttgtcttca catattgcta aagaagtctt agactacttt
     4381 aacccattcg tgattactgc agtatttaga gtttatgcag aagaattgtc agaagcaaga
     4441 gaacatccat taactaagag acgttatatg tggaaactaa cttattaaaa aatagatcaa
     4501 actaaataag gtggcttgag aaattaagcc accttgtttt cttcaatgtg attttataca
     4561 tatggtaaaa taactagtac atattgtgaa agcaggtggc aagatgcagc gattaaatga
     4621 ctatctttat caactaacat tgcttttgaa atctacgcct tcagataatt attcagctcg
     4681 cagtatttcg caagctttac agttgaatag aagtacaatc agtagctact taaatgaagg
     4741 tgttcgtgaa gggcttttca taaaagtaaa aagttacccg gttttatttt tacatagaac
     4801 agctcttgaa gaactacata tcacactgaa taactccgaa atagaatcaa ttgaaagctt
     4861 gttaacaatt tctcaaaaac ccgcattaga tcaagtaatt ggctctaaag gaagtttgaa
     4921 agaagcaatt gatcaaatta aaacggcagt cttatatcct ggaaaagggt tgcctttatt
     4981 attgatcggc gctagtggat cagggaaaac ctttctagcg aataaaatat atgaatatgc
     5041 agtagaagaa aaggtcattc acacatcggc acctttcata gattataatt gtgcacaata
     5101 tgtgagcaat ccagagttac tatcctctgc tttatttggc tacacgaaag gagcatttac
     5161 cggagcaagc caggagcata ctggtttgct agaaaaagcc gatggaggag tattgttttt
     5221 agatgaagtg catcgcttat ctgaagaagg gcaagagaaa ttatttacat ttatggatac
     5281 gggtgaattc tctcctatgg gggataatag tattcggaaa aaagccgatg ttcgattagt
     5341 ctttgcaaca acagaaaata tatatacgac tttcttacca acttttctta ggagattgcc
     5401 agttattgtt aatctaccta gatttcaaca acgtccgtcg tttgaacgtc tgtcattgat
     5461 tgatgaattt tttgtttctg agagtaaaat tttagctaag gaactatctg tttctgatgc
     5521 attgattcat ttcttaatga atagtgattt tgaaggtaac gtggggaata ttaaaaatat
     5581 tatcaagtat gcttgcggaa acgcatatat ccaccagaag agtcagcaaa caattcaagt
     5641 taaattattg gatatgcctt tagagtacag ttataaattc aaggagcaac taaataaacc
     5701 cagaaagaaa agagcagatc gaatctacta tccagaagaa acacgacaag tgcaactaga
     5761 aagaaacaat cagctttttg ttcaattttt tgaccaatta cttactggat tctctgaagt
     5821 gattgaaaat aacaaggata ttaaactatt tttagaagaa atggttacca aggtaacaca
     5881 agtaatggat acgcttattt ttcaagagga ttacgaaaaa gagcagtctt tatacgccat
     5941 tctaaactat catattcgtc aaagtattga ttttatgcga gaaagctacg ggtttgaaca
     6001 agatggtaac cgggtagtcg ctttggccaa ctatctatat gtcaaggata atcaagtgat
     6061 ttttgaaaat agtcttcaag aaaagaaaac caaagatcag cttaacgaat tttttgctaa
     6121 tgttcttgaa accccttatt ggtatgcaaa aaaaatctta agccttttat ctgagtgttt
     6181 agatcaacct gtgtatgaag aggacatttt ctttattacg ctatattttt atagtttgaa
     6241 tgtcacgaat gttaaaacag gtattaagag tattgtgcta gctcatggtt attctacagc
     6301 tagtagtatg gcgaatgttg ccaaccgtat gctgaataag aacgtttttc aagcttatga
     6361 tatgccttta gatattacat tagagaaaat tgaagcaaaa ttgattcaat tccttggaga
     6421 ttatcgaaca gattcaggct tgattttatt ggtagatatg ggttcactaa accaactagg
     6481 cggtttatta gtgaatcatc taaatggacc actgttaatc attgatcata tcaatacacc
     6541 gttattattg gaagtcggcc aacaagtatt aaacaataaa agtatcaccg aaataggagc
     6601 agaaattgaa acaagtctta ctttcaaaaa gcagttacta cttcccaaga aaaagaaaaa
     6661 gaaagccatc attacttgtt gttatacagg gattggtagt gcgacccaga ttcaggagat
     6721 tttaacgaaa tgcttgaaag atgcagttag agaattagta attattccgt atgattacaa
     6781 aaagctgtta gaaaacaaga attttgagac tccttttcaa ttatacgatg tcatcatgat
     6841 tgtaggtaca gaagatccca aaattaatca gattccatat attggattag atcgcctgat
     6901 taatggggaa gcaattggcg aatttgttca ttacttggaa aaagagctga ctattgaagt
     6961 gaacgattta caaaaagaat taattttcaa tttttcaatt agtaaaattg tcgaaaattt
     7021 aaccattttg gatccagata aggtgctatc ttttgtacaa aaagcaatta aagaattatc
     7081 gaagttatta aattttgatt tttctaataa tcagctgttt ttgttgtacc ttcactgtag
     7141 ttgtatgatt gaacgaattg tacgtaaaga aagtgtggat gagcaagagg acattgaaga
     7201 atatatgcaa gcaaatggag aaataatgga taaaattcat agcgcttttt ttgagattga
     7261 aagggaatac acaattgaaa taccagattt agagttgcga ttattgagcg atattgttca
     7321 aggataggag tgaattcgaa tgacaatggg agtaattttt gatatggatg gggtactcat
     7381 agacagcgag acattttatt ttgagagaag aatgaacttc tttcaagaac tggagataga
     7441 tccaggatca aaccagattg atgattatgt ggggaaaaca gaagctgcaa tatgggaaac
     7501 attagttcct gaggacaaat cattaagaga ggaactttat ccgaaatatg tagattatcg
     7561 aaaaacgcat ccaattgatt tcgctaaaga tttacgaaaa gaagtgaaac cgttacttga
     7621 cttcctcaag aagcgggata taccattggc actggcatct tcttctccag ttgttgagat
     7681 agagagtatg ctcattcaat gtgaacttac tgaatatttt tcctttgtta taagtggtga
     7741 gtcattaaaa caaagcaaac cacatcccga aatatattta aaagcgaaac agcaattaga
     7801 ctgtgacttc tttattgcag tagaggattc aacgattggt attaaatcag caaaggcagc
     7861 aaatatctat acggtggcac taaaacaacc aatgcaaatc gatcagagtg aagcagacat
     7921 acaaattgaa agtctacaag aactggaaca aattgtttta gaaaaaggtt agtgaattaa
     7981 tggaaataag gctatatatc tgtgctagct attttgacta accaaaaaaa cttgctataa
     8041 ttcaggtgta gtaaaaggtg ctggtaacac cttttacgaa aatgcttcgg cagtgataat
     8101 gggattggct ttttaagttt tttattttgt tcgcaatccc taaggtcatg tgaatgatcc
     8161 tagggattgc tagaatattt tgcaacattc tatctatttc agaacgtaac cttccccagt
     8221 tcattgggat tcattagcat acaaccaaca tttcaaaaag aaattgcact acaccattat
     8281 tagctatttt gactaacccc aaaaaacttg ctataattca ggtgtaggta aaaggtgctg
     8341 gtatcacctt ttacgaaact gcttcggcag tggtaatgag tgtggcttaa aggactagtc
     8401 ctttaagctt tttactttgt tcgcaatctc taagatcaag ttaatgatcg ataagattgc
     8461 tagaatattt tgcaacattc tatttcagaa cgtaaccttt cccattccac tgtgattcat
     8521 tggcaaccct cctcacaacc aacgtttcaa aagaaattgt aaagttgttg gggtaccacg
     8581 accgaacaat actacacctg aatgatagta agttgtctca ttaagtatag catatcctct
     8641 ttttgggtaa atagaaatcg gttacatttt ttatccaaga ccaagttttt tcatttggtc
     8701 ttatttgcta tacccaaaca attccgcagt atagtcgacg gtattgattt tatcaggtga
     8761 gtaatagaaa cttgttttcc ttccccaaaa cattacctat aaaggagaaa aaatggtatc
     8821 gtaattatat aggtatagga tgaaattttt ttctaagagg agggttgttg atgaaaaatt
     8881 tacagttaaa atttattgtt gatccatcga ttgtacgctg gtttcggatt atcaatcaat
     8941 ttgagcgcaa tcaacttgcc acaaaaggag aattagcaaa gagtaatcat gtatctgaac
     9001 gaaccattca aacagatgtc aataaaatga aggactactt ttctgaaagt gttcaatttg
     9061 tttcaacgaa aagtgggtat tcttttcaga aggaaagacc ggttcttttt ctcaagcaga
     9121 aggagcaact actggagaac gaaattttat ttgagttgtt agggaatgtc ttttatggcg
     9181 aattggaaga tatgacggag ctaattgatc gttttcattt atctgaagcg acttttcgtc
     9241 ggtatttgaa gcagattcaa ccagttttgg aagaatacgg cttagaattg agtctttatc
     9301 ctcttgattt aaaaggagaa gaggcaaata ttcgcaagtt ttttaaagac ttctattatg
     9361 aaggggagat gacgccccat actcttgttc caccaaggga tcttcatgaa cttgtgcaag
     9421 ctacattcta tgataaattt gagtatttct cgattggaac agggacttct cctgctgaat
     9481 tttattatag tttgtatatt gcgattgagc gtgtgagaca aggaaaaacg atagccattc
     9541 ctcaaggtct gattgagcga gtaattgcta gtgagaattt tcgcttaatg tattccttga
     9601 aagaagcgat tcaaacaaat tatcaagttg ctttatcaga agaggagttt tgttggttgt
     9661 att
//
LOCUS       DAZKKZ010000088         9550 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.090, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000088 DAZKKZ010000000
VERSION     DAZKKZ010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9550)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9550)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9550
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.090"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(59..1099)
                     /locus_tag="ACG8LA_002563"
     CDS             complement(59..1099)
                     /locus_tag="ACG8LA_002563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HFQ0204834.1"
                     /translation="MTDFNFFKADRVYNELFYQFPKVFIVSDEYKKMKDSTKIAYMLL
                     KARLEIAISKRQIDEEGNVYFTYTTNELCSVLNCQKQKAIAIKKELESFGLLLQKQMG
                     FNKQLGKNNPNRLYLAELKVSENDIYLLEKFDRENRENVDKSEGMKIIPTLDEKSDAE
                     SLGAQEGMKIIPCQNVDKSEGMKIIPELNNNILDTNRHNIDTEKDRLQDQLLLDNFET
                     IMTNDSIATFIPERVLNLIKTFSSSYSEAQKTVQTIHNAKKKAETESGISIIFEELDS
                     YYVNAEQELYTTLLKAYQKLKTEKVENIQNLIFVYVKNWFIEKPIAAKVSSEKRLNSE
                     SFPKTITKDWLE"
     gene            2265..2351
                     /locus_tag="ACG8LA_002564"
                     /pseudo
     CDS             2265..2351
                     /locus_tag="ACG8LA_002564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339775.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
     gene            2905..3129
                     /locus_tag="ACG8LA_002565"
                     /pseudo
     CDS             2905..3129
                     /locus_tag="ACG8LA_002565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877485.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            3389..3643
                     /locus_tag="ACG8LA_002566"
     CDS             3389..3643
                     /locus_tag="ACG8LA_002566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HFQ0204835.1"
                     /translation="MGKELKVRKIGNSVGVILPSSLGLKSGDTIQAKQEGNLFILDTT
                     QIAKEHDRKLIEESFQDFEKGLTVSEIEMVKAFGKYGWSE"
     gene            3644..3961
                     /locus_tag="ACG8LA_002567"
     CDS             3644..3961
                     /locus_tag="ACG8LA_002567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA];
                     GO_function: GO:0042803 - protein homodimerization
                     activity [Evidence IEA];
                     GO_process: GO:0030541 - plasmid partitioning [Evidence
                     IEA];
                     GO_process: GO:0051290 - protein heterotetramerization
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HFQ0204836.1"
                     /translation="MKEYTLVYSKSFQTSLETIIEEWENELALSPASIKRFVGAIQKA
                     LELTKNFPTMHEEVSEIYGMDIPTYRIVIGKSYALFYRIDHEKKEILVGRIFQSKQMK
                     LGF"
     gene            4520..5446
                     /locus_tag="ACG8LA_002568"
     CDS             4520..5446
                     /locus_tag="ACG8LA_002568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204837.1"
                     /translation="MNILNEKRYVWFAGKKYITTFKRLSELMQQTVKSAMPEGYKFNF
                     VQSSVSTESIYFSILSESRLFHFRISSHVKKTDVDIYMFRTNNYKNLNDLSRSISEYL
                     KGNSYLKIRFSHILILLPYLNENFTLIQVDKSFIASGNQGNMNITSNKTSRVLLALMG
                     YGILYRDDQNGQIIITRAGRSLLMKYRKFIPEDFQNLQLENMRLEDLFRLAEDDKYRF
                     EVLKIQKNELLNKLYPENAIKAHFGDANHMYSWFIPKRFRGKINAGDQVKVLNRNSTD
                     VVMITDIYVEDEDIIKYMKPVIKLVNKNKGNG"
     gene            5552..5815
                     /locus_tag="ACG8LA_002569"
     CDS             5552..5815
                     /locus_tag="ACG8LA_002569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0097351 - toxin sequestering activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0045927 - positive regulation of growth
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HFQ0204838.1"
                     /translation="MAKTVLNPSTARKNFYKLLKDVNENHTEIEIISERSENNAVLIG
                     LDDWKAIKETLLLEQIGTLGVVRKREKDDSGFTNVDEIDWDNL"
     gene            5815..6087
                     /locus_tag="ACG8LA_002570"
     CDS             5815..6087
                     /locus_tag="ACG8LA_002570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008219 - cell death [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HFQ0204839.1"
                     /translation="MNNYSVMIKNSAKADLKKIKQSNLKPQFEKVIQTLKEDPYLPTQ
                     SFEKLKPTHEGRYSRRLNRQHRVVYKVDEDEHVVEIYSARTHYESQ"
     gene            6164..6493
                     /locus_tag="ACG8LA_002571"
     CDS             6164..6493
                     /locus_tag="ACG8LA_002571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HFQ0204840.1"
                     /translation="MITKTRKQGNSIMLTVPKDFNVPNGVEVEAKLVENGILYEFVEP
                     QKEFYDFSEDILSDIIAEGYDKDEILVEFKNRKNKMHSSFRDIAEDTLTNSKVMTKEE
                     LATEIGL"
     gene            6483..6770
                     /locus_tag="ACG8LA_002572"
     CDS             6483..6770
                     /locus_tag="ACG8LA_002572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HFQ0204841.1"
                     /translation="MAYEIVPSKHVIKYLKKLKEKPLKEKFLNLIYDEIAIDPYKGEQ
                     KTGDLSGIWSSGFKYAGTTYRVAYEIIENKVIPVLLCGTHENFYEQLKKLI"
     gene            7056..7913
                     /locus_tag="ACG8LA_002573"
     CDS             7056..7913
                     /locus_tag="ACG8LA_002573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HFQ0204842.1"
                     /translation="MVAKKYVIGNFKGGVGKSTCAQMLGFESAVNEGKRTLIIDLDMQ
                     GNTSDVMNLTHMNFTNEEGGGEGEPIVYENTVTDVLINNLPPKEAVYKVINNLYILPA
                     DMSFEMYDDWIKDQYNDSLSQFKYMKEKLEPLFDEFDVIYLDVPPSISVYSKSAMYIA
                     DWAIVVLQTQVKSMRNAMQYLEYMDFFVKEFDTNLYVAGVIPFMLESGDAVDQEMYKQ
                     AQEIYGEHLIKNVVLKNARLKRYDGSGITMEKTKKGLLKQWDRKSHELFISILKELEE
                     HENWYAEVE"
     gene            7914..8462
                     /locus_tag="ACG8LA_002574"
     CDS             7914..8462
                     /locus_tag="ACG8LA_002574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204843.1"
                     /translation="MADIKGLDIFGNNKGLAKIKKEAEAKKKQQAITPSENKQLEVHQ
                     VQEIKTSSNVERQSRGRTKKVGAPIRKFDKVYSTKHPLKLSTLLNATSRVLVEKYETN
                     MTRDELLRKALDEYIKQNLTQEDKQDLFNDVVKELDLFREKYPIVPELDDRGEIIRTT
                     SQIKQDTEDSLRKGWGMNNKVR"
     gene            9238..9550
                     /locus_tag="ACG8LA_002575"
                     /pseudo
     CDS             9238..9550
                     /locus_tag="ACG8LA_002575"
                     /inference="COORDINATES: protein motif:HMM:NF012311.4"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
BASE COUNT         3454 a         1288 c         1717 g         3091 t
ORIGIN      
        1 aaaaattttt aattttaatg ctactccatg aagcaacaat caatttgtca gtgaaatttc
       61 actctaacca gtctttcgta atagtttttg ggaagctttc agaattcaaa cgtttttcac
      121 ttgatacttt agcagctatt ggtttttcga taaaccaatt ttttacatag acaaaaatca
      181 ggttctggat attttcaact ttttcggttt ttaatttttg ataggctttt aacagtgtcg
      241 tgtataattc ttgttctgca ttgacataat aactatcgag ttcttcaaaa attattgaaa
      301 taccactttc tgtttcggct tttttctttg cattatgaat agtctggaca gttttttgag
      361 cttcactgta acttgaagaa aatgttttta ttaaatttaa tactcgttca gggataaacg
      421 tagcaatgct gtcgtttgtc ataattgtct caaaattgtc taacaacaat tgatcttgta
      481 ggcggtcttt ttcagtgtct atattgtgtc tattagtgtc taatatatta ttattaagtt
      541 ctggtatgat tttcataccc tctgatttat caacgttttg gcacggtatg attttcatac
      601 cctcttgagc cccaagggat tcagcgtctg atttttcgtc gagggtgggt atgattttca
      661 taccctctga tttatcaacg ttttccctat tctctctatc aaatttttcg agtaagtaga
      721 tatcattttc tgagactttt aattctgcta gatatagtct attaggatta tttttcccta
      781 actgtttgtt aaatcccatc tgcttttgta ataataaacc aaaggattcc aactcttttt
      841 tgattgctat cgctttttgt ttttggcagt ttaatacgct acatagttca tttgtcgtat
      901 aagtaaaata aacattacct tcttcatcga tttgccgttt gctgattgcg atctctaatc
      961 ttgcttttaa aagcatatag gcaatcttag ttgaatcttt catttttttg tattcgtcag
     1021 aaacaataaa gacttttgga aattgataaa ataattcgtt gtaaactcta tccgccttaa
     1081 aaaaattaaa atcagtcatt gtagatcctc tactttcacg ttgttttatt tatgtaaaat
     1141 tacctactct tttcgaaaat agcaaagata aataaaaaat gcaaacgcat taaaactgtt
     1201 ttttaattaa atactaccta aaatcagaaa taaaatgaat tatgtactac ctttaaagtc
     1261 attaagaact actttaaata aatattattt ataattaaat actaccagaa gaacgtatga
     1321 ataaaattta gttttaaaat taaagataat taagtactac cagtgtcaaa acaaaaaata
     1381 aattaagaac taccttatgc atataaaaca tactaccatt actagtaata tatactacct
     1441 tatttcagta gtatatatta tattcttctt ataagacaag gctttaggct agaaaacaat
     1501 agattatata ctactaaaaa atacaataag tactaccaat gtcagatata tataataatt
     1561 atgtactacc attaaaatta acttatttaa taagatacta ctgtgttaat ctgaaaaaaa
     1621 ttactttaaa gtagttacat actacctgtt aaattagata ctaccattaa tacttaaatt
     1681 agatactacc tatatttata ttaagtacta ccgttctagg aataagataa taaaaaaaaa
     1741 ctaccaaatt gcaattaaat actacttaaa atgtaaaaaa taagaactac ccaaattagg
     1801 tagttcttaa taagagaata tcagataaat ttgtacaagt cataaaaaaa ttaatcttaa
     1861 atttttaaat atatatacct gttaattata aactacttta tttaggtagt acataattaa
     1921 cagataaaac tacatgcttg tagtttgtct agctaatgag ttgcatatga tttatataaa
     1981 ggtgtgcagc ataacttagt tgaagttaag agaatagaat aaatattttt tgttttgcta
     2041 ataattaaac actacctaaa tatggtagtg tttaattata taatattcat tttgttacaa
     2101 ataatcgtat tataaaagca taacaattgg gataactatt ttttagatta tttaagtact
     2161 acttaaatta ggtagtactt aaattttggt ttaaggtagt aggtaattaa gaaataatat
     2221 atatcttctt ttataataga aggggagagg cctagttaaa aacagcgaca attaataaca
     2281 atgtatttaa tgcttcacaa aatccatttg gtggacaatg cattgttatt agcgatgatc
     2341 taccgttcta agtagttttt tctattggtt gcattcgtga ctaattatgg tataattatg
     2401 agtaacaaag aggtatttca ttatatcatc aaaccccatc agcgtgtagg ctgatggggt
     2461 tttttttacg tttctatatt atagaattaa ctggtaggct tactgtcttt tttggcaatt
     2521 ttgcaatcaa gccacttgca gatgtagtgt gcagttacct ctgcaaatgg cttgattgca
     2581 aaaacaaaat caaaaaggta tttcattata tctcctcctc cccttgccag attaggccgg
     2641 ggtagcagac agcaaaacta ttataacata actgaaatac ctaaatgaca tatacagata
     2701 tgataattta tgtattgatt tttctaacaa aagcacatat tttaatatat actacctatt
     2761 ttaggtagta tatattttta gatacaatat cgatcagttt tgaggaaatg aaattctaga
     2821 tattttttgc tacatagagt tactttcaat attttttaac gtaattaggc agaagtcact
     2881 catcctctat aggtttgtga tgaaattgct attgatccat ttaagtaaga gcaaaaaact
     2941 ggaggtttat caggtaattg gtctaatgga tttaagtatg cggtcaccgt gtatagagtt
     3001 gcttatgaga ttcaagaaaa taaagttatt ccagtattgc tatatggaac acataacaat
     3061 ttttatgaat tagccgagaa cactcgcaac tttattcgtg tagatgaatc ggcttcggtt
     3121 gagttataac tttagctata tcaatcaacc gaccgacata tgttaaatct atatataata
     3181 aaaataccta cttaaatgga tgttaacgga agtgtatggt gagtagttca ctcgtatttt
     3241 gatatcgttt gtatatgttt tcagcgttct aagtggctta ttttgtccaa taataatatg
     3301 gagtggaatc ccttaagaaa caccgttggc aattgtcgtt ataacatgtt ataatttatt
     3361 tatcaaaaac taaaagaagt gtgataacat gggaaaagaa ctaaaggtta gaaagatcgg
     3421 caatagcgtg ggagtgatcc ttccaagctc tcttggatta aaaagcggag acactatcca
     3481 agccaaacaa gaaggcaact tattcatatt agatactact caaatagcaa aagaacacga
     3541 tcgcaaattg attgaagaaa gtttccaaga ctttgagaaa ggtttaacag tttcagaaat
     3601 tgaaatggta aaagctttcg gaaaatacgg ctggagtgaa tagatgaaag agtacacgct
     3661 agtttattct aaaagtttcc agaccagcct tgaaacgata atagaagaat gggaaaatga
     3721 gcttgctctt tctccagcca gcataaaaag atttgtaggt gcgatccaga aggctttaga
     3781 actaaccaaa aattttccaa ctatgcatga ggaagtttcc gaaatctatg gaatggatat
     3841 cccaacatat cggatcgtga tcggcaaaag ctatgcctta ttttatcgga tcgaccatga
     3901 aaaaaaagag atacttgtag gacgtatttt ccaatctaaa caaatgaaac taggctttta
     3961 acaataatta ggcaaaagtc gctcatcctc tacaggtggg tgattaatgc cgctcgatat
     4021 ggttgttaac cgtcggttac tcgaagattg atatataaga cttagtacct ttttattttg
     4081 ctccatgtta tggccgaagg tctaaagata caatcattag tctagagaaa aattaagaac
     4141 cgtaggaact acggggatcg cttggtgaat aagagacact gctattagtg aaaaaataag
     4201 atatcaagta cgctctattc ccaaaaattt cgtgacttta ctcatgagag gttcaagtag
     4261 tatattttta atcaaaattg acgtaacttt taataaatac tacctaaata aggtagtatt
     4321 tatttttgtg ttttaaaaga ggaagtccaa tatatctatg ggaaacttct taaatattat
     4381 gttggtacat gaaaatatac atccctgcta gactatttac aacattttac tttgtacgta
     4441 ttcttgtttt aaaaggaatg ggataaaata taggtacaat aactatttga tgctaaatat
     4501 aattaatgga ggagagatag tgaacatact taatgaaaaa agatatgtat ggtttgctgg
     4561 taaaaaatat attactactt tcaaaagatt atccgagtta atgcagcaga ctgttaaaag
     4621 tgctatgcct gaaggataca agtttaattt tgttcaatct tcagtatcta ctgaaagtat
     4681 ctatttttca attctttctg agagtaggct ttttcatttt agaataagtt ctcatgtaaa
     4741 gaaaactgat gttgatatat atatgttccg tacaaataat tataaaaatt taaatgattt
     4801 gagtagaagt atcagtgaat atctcaaggg gaatagctat ctcaagattc gattttcaca
     4861 tatattaatt ttactaccat atttgaatga gaatttcacc ctaattcaag tagataagtc
     4921 tttcattgcc tcaggtaatc aaggaaatat gaatattaca agtaacaaaa cgtcacgtgt
     4981 gctattggcg ttgatgggtt acggaattct ttatagagat gaccaaaatg gccagattat
     5041 aataactcgg gccgggcgtt cattattaat gaaatataga aaatttatac cggaagattt
     5101 tcaaaactta cagttagaaa acatgcgttt agaagattta tttagattag cagaagatga
     5161 taagtataga tttgaagttt tgaaaattca aaagaatgaa ctattgaata agttatatcc
     5221 tgagaatgcg ataaaagcac attttggtga tgctaatcat atgtatagtt ggttcattcc
     5281 taaaagattt agagggaaaa tcaatgctgg agatcaagtg aaagtactca atcgaaatag
     5341 tacagatgtc gtaatgataa cagatatcta tgtagaagat gaagatataa tcaaatatat
     5401 gaagcctgtg ataaaacttg ttaataaaaa taaaggaaac ggataacact ttacaatgct
     5461 gttttggtac tccaatttaa acaaaacaat cgaatttacg tacttaatta agtacgttag
     5521 aatggagata taaattagag ggggagtaga tatggcaaaa actgtcttaa atcctagcac
     5581 agcacggaaa aatttttata agttgttgaa agatgtaaat gagaatcata cggaaattga
     5641 aatcattagt gagcgcagtg aaaataatgc ggtgcttatt ggtttggatg attggaaagc
     5701 aatcaaagaa acgctattac ttgagcaaat aggcactttg ggtgttgttc gtaagcgaga
     5761 aaaagatgat agtggattta ctaatgttga tgaaattgat tgggataact tataatgaat
     5821 aactattctg tgatgattaa aaactcggct aaagctgatt taaagaaaat caaacagtct
     5881 aatttgaaac ctcaatttga gaaggttatt cagactttaa aggaagatcc ctatctccct
     5941 acccaatcat ttgagaagtt aaaacctaca catgaaggta ggtattctag aagattgaat
     6001 agacaacacc gggttgttta taaggtagat gaagatgaac acgtggttga aatttattca
     6061 gcaaggacgc attacgagtc acagtaatta cttgtaaata cattatctcg tggtataatg
     6121 tatttactaa gtaattacat actgttagaa atgagggatt taaatgatta caaaaacaag
     6181 aaaacaaggc aattcaatca tgttgacagt acctaaagat tttaatgttc ctaatggagt
     6241 cgaagttgaa gcaaagttgg tagagaatgg tattctttat gaatttgttg aaccacaaaa
     6301 agaattttat gattttagcg aagatatttt gtctgatata attgcagaag gctacgataa
     6361 agatgagatt cttgtagaat ttaagaatag aaaaaacaaa atgcattctt cctttagaga
     6421 tattgctgaa gatacactta ctaattctaa agtaatgact aaagaggagt tggcaacaga
     6481 aattggctta tgaaatcgtt ccttcaaaac atgtcattaa gtatttaaaa aagctaaaag
     6541 agaagccatt gaaagaaaaa tttttgaatt taatttatga tgaaattgcg attgatccat
     6601 ataagggtga acaaaaaact ggggatttat caggtatttg gtctagtggg ttcaaatatg
     6661 cgggcacaac atatagagta gcttacgaga ttatagaaaa caaggttatt ccagtattgt
     6721 tatgtggaac gcatgaaaac ttttatgaac agttgaaaaa attaatctag tgatttgttg
     6781 tcgttcttaa gaaggacggc ttctttttta tcgaaaatct gattcgtcta catgactaaa
     6841 gtcgcgagta ttctctgctt ctcgataaat taaataacgt cattactttg aggaaagcta
     6901 taaatcaata tatttcagct tttccttatt tatgtactac cttttactta ttaattataa
     6961 ggtagtacat atatatcttt tttttggtag taactaaaaa taaatatgtt ataatagtat
     7021 caaatgaata ttgctaaaag aaaagaggta ggaacgtggt agcgaagaaa tatgtaatcg
     7081 gtaattttaa aggtggcgta ggtaaaagta cgtgcgcgca aatgttaggg tttgaatcag
     7141 cagttaatga aggaaaaaga accttgataa ttgacttgga tatgcaagga aatacttctg
     7201 atgtgatgaa cttaacgcat atgaacttca ctaacgaaga aggaggcgga gaaggtgaac
     7261 cgattgttta cgaaaatact gtgactgacg tgttgataaa caatcttcca cctaaagagg
     7321 ctgtctataa agtaatcaat aacctctata tacttccagc agacatgtcc tttgaaatgt
     7381 atgatgattg gatcaaagac caatataatg attcattatc ccaattcaaa tatatgaaag
     7441 aaaagctaga accattattt gatgagtttg acgtcatcta tttagatgtc ccaccttcta
     7501 tttctgtata tagtaaatcc gcgatgtaca ttgcggactg ggcaatcgtc gtcttacaga
     7561 cccaagtaaa atcgatgaga aatgcgatgc aatatcttga gtatatggac ttttttgtga
     7621 aagaatttga tacaaattta tatgttgctg gtgttattcc tttcatgttg gaaagcggtg
     7681 acgcagtaga tcaggaaatg tataaacaag cccaagagat ttatggggaa catttgatta
     7741 aaaatgttgt actcaaaaat gcgcgcttaa aacgatacga cggatcaggt attacgatgg
     7801 agaagacaaa gaaaggtctc ttaaaacaat gggatcgcaa aagccacgaa ttatttatca
     7861 gtattttgaa agaattggaa gaacacgaga attggtatgc ggaggtggag taattggctg
     7921 acatcaaagg acttgatatt tttgggaaca acaaaggact cgccaaaata aaaaaagaag
     7981 cagaagcaaa gaaaaagcag caagcaatta caccatctga aaataagcaa ttagaagtgc
     8041 atcaagttca agaaataaaa acttcctcca atgttgaaag acagagtaga ggaagaacaa
     8101 aaaaagttgg cgcaccaatc agaaagtttg ataaggttta ttccaccaag catcctttaa
     8161 aactgtcgac tttgttaaat gcgacttcca gagttttagt agaaaagtat gagactaata
     8221 tgacaagaga tgaattgctt agaaaagctt tagatgagta tattaaacag aatcttacgc
     8281 aagaagataa gcaagatttg tttaatgacg tggtgaaaga actagacttg ttcagagaaa
     8341 aatatccaat tgttccagaa ttagatgatc gtggagaaat aataagaact accagtcaga
     8401 taaaacaaga taccgaagac tcactgcgca aagggtgggg aatgaataat aaagttagat
     8461 aataatcaaa gaagaactaa gtaactacct ttaaacggta gttacttagt tcttctttga
     8521 tttgcgtgaa atagagagga tttatttttc tggttacgtg attaaaaaat ccaaaaaatg
     8581 agcataggaa cggttatgat tttagggtgt gttttaatga gatattgtaa tttcattaac
     8641 aagtgtatga taatctgttg ttgagttagt aaataagtaa tagagctaac tctaaaataa
     8701 aactattagg aggagatgta gatgaaaaag tttaaaaaga aaatatattt aggattggtt
     8761 gttggggtga gtatgtttgg gttcgtggct cacactaaac aagtaactgc agatactaac
     8821 caaaaagaaa ggattatgag ccaattagat gactctcaaa tagagtatgt acccaatgag
     8881 ctaattgtca gtttaaaggc tacacaaaga atttcaacag agaaaaataa accgcaaaat
     8941 ttattgggtg taaaagttat ggtggaaaaa gatttgactc ttaggacaaa tgaaagcgat
     9001 tataataagc gagatcaagt attattagtg aaattgaacg aagaaattag tgtggaagag
     9061 gcagtaaaaa catttaatgc ttctgatatg gtcaattatg cagagccaaa ctatgtggct
     9121 gaactagagc cgttgaatga tgttgaggag ccaaatacaa ctgattcttt aggaaatcga
     9181 tcaattattc ttaacgatcc taattggagt aaacaagcta atttaagaga gattagcatg
     9241 ccatccgctt gggaagaaac caagggttct aaggatgtga aggtagcggt cattgattca
     9301 ggaattgatt atcaacatga agatctttct ggaaatgtag atgaaagttt gagatacgat
     9361 ttttttaacg atgatacaga tcctatggat actatgggac atggacacat attgccggga
     9421 ttattggtgc tcaaacaaac aacgaattag gtgttgctgg aataaattgg gatgttacga
     9481 tggtacctat acgtgtattt ggtagtagtg gaggtaccag tttggcaatc ttaactgaag
     9541 ctattaatta
//
LOCUS       DAZKKZ010000089         8425 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.091, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000089 DAZKKZ010000000
VERSION     DAZKKZ010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8425)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8425)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8425
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.091"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..506)
                     /locus_tag="ACG8LA_002576"
     CDS             complement(<1..506)
                     /locus_tag="ACG8LA_002576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204844.1"
                     /translation="MISIIWFLFFFIFFSYLKVIKIDSFLVYHTSAMKNLTQNLLKKD
                     NSSILKIELKKENNKSMKISKKAFLLVVLILLSTLYSVNFMRNAQEIYTTGDLSFHLS
                     RIKGLSSIFEGPINYTTFNNYGDGLNYFYPFLTIIPAVVFYGISNNLILSYVLYIWLL
                     NICTILIS"
     gene            472..2109
                     /locus_tag="ACG8LA_002577"
     CDS             472..2109
                     /locus_tag="ACG8LA_002577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204845.1"
                     /translation="MKKNKNQIIDIIFMLFLSFAYVIPLFMSMGIYHSVNQDTYFHLS
                     RIIGLDNVWSSPVNFNNFDHHGTMMNIFYPWLTLYPAFLFYKMMGNLVLSYNIYYFFI
                     TFLTMVVSYFSMKQIKNNRYISLLFSIIYTFSAYRAIDIFHRASLGEAVALTFLPLIL
                     MGCYEIYIRDYQKWYWLSIGMTLVVYTHLLSVAMVSVFIGGTLFLSFYFWDQKIARLL
                     SLLKATVLTFFLSAGFLIPFIQQSRAQELKVPLGKELSGMAPSDMLTHILNNNYNNYT
                     IGLFLFLGLIGAFIFIKKLTADDLFIFFLGVFVLFCSTNLFPWQLFNHTPVKSLQFVW
                     RLNGFSSLFIAYTMSIVIYYIFSTKNNSWKIMVFTFLALILHLSGVSNSIHANKDSLT
                     LIAPEDAVAIAENYNHTDYANKESIYHPDMINNDQYLLGNQEINPTTHFMSNKLTIEL
                     DNSNNKNTVLTTPIYRYKGQVASINGKLVQTKLSKFGTTELTIPPGINKVVITYQYTK
                     LAIASRYLSIVTLILFLLYRFTFSKQKQPRREVQHSH"
     gene            complement(2254..2994)
                     /gene="truA"
                     /locus_tag="ACG8LA_002578"
     CDS             complement(2254..2994)
                     /gene="truA"
                     /locus_tag="ACG8LA_002578"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HFQ0204846.1"
                     /translation="MRNIKLTIEYDGKRYSGWQRLGDDDKTIQGKIEKVLHQMTNEEI
                     EIIGSGRTDAGTHARGQVANFKTNTEIGLAEMIDFMNRYLPRDIVIKRIEEMPERFHS
                     RYNAVGKKYSYYVWNNVIPSAFERNHSFYFPQELDMDKLNAACEKLVGTHDFIGFSAL
                     KKSKKSTVRTIDELSIERKGEMLHFTFVGDGFLYKMVRIIMGTLLEIGTGAMPIETID
                     EIFESKVRQHAGETVPAQGLFLDEVYYR"
     gene            complement(3185..3820)
                     /locus_tag="ACG8LA_002579"
     CDS             complement(3185..3820)
                     /locus_tag="ACG8LA_002579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HFQ0204847.1"
                     /translation="MDFLRKFGFFFLLLGVLSDFLTPYVLGLYYPELDQMKSVISVFG
                     EVSSPVRKAFLIWSVVSGIFFILSLPALYAAFVSTSRVLATLVTAAIAFYGIGDCIFT
                     GLFSINTHESSWNVSTWVHNIGSGLGYSGFLLFPVLLFLIYRKNGQMDVSHLYLGLSV
                     ISLLFAAIYGLARIPSINSWPLLNKIGFCQRISFFFNYVPIAWLSILHLKQ"
     gene            complement(3967..5187)
                     /gene="sstT"
                     /locus_tag="ACG8LA_002580"
     CDS             complement(3967..5187)
                     /gene="sstT"
                     /locus_tag="ACG8LA_002580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA];
                     GO_process: GO:0015826 - threonine transport [Evidence
                     IEA];
                     GO_process: GO:0032329 - serine transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
                     /protein_id="HFQ0204848.1"
                     /translation="MSLVQRIVVGILVGILFGIFFPTWTFISILGTLFVSCLKAIAPI
                     LVFFLTMASIAKHKIGNKTFVKPILILYLVGTLLSALVAVIVSSIFTVPITLQETVSE
                     KAPQSLESVLSTMLTNVTQNPVQSLIDANYLGVLFWAVLLGLAFRARSESTKELVDQI
                     SIALSQVVQVIIAFAPIGILGLVYQSIATTGIAGLAEYLQLLLVLIGTMLFVALVVYP
                     FLTFLFIKENPYPLIFFCLKESALPAFFTRSSAANIPINMMLAERLKLTKESYSISIP
                     LGATINMGGAAITISLMTLTAVHSLGIEAPFVLKVLLCILSALAACGASGVAGGSLLL
                     IPLACSLFGISNDVAMQIVGIGFIIGVIQDSMETALNSSSDLLFTAIGELGARKRSGE
                     KIKLKDCLDGLSER"
     gene            5755..>8425
                     /locus_tag="ACG8LA_002581"
     CDS             5755..>8425
                     /locus_tag="ACG8LA_002581"
                     /inference="COORDINATES: protein motif:HMM:NF013080.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HFQ0204849.1"
                     /translation="MNIRDYWLILTPISQNYFTYAVSCTLLFCSIPYTVGFLNKLSKT
                     TIKYLLLFLTIGLVGCSTLFNKDPFALQNGQSILWIFYLFLMGYGLKEWNWKEKVRYK
                     LPQVFISLIVLFGLIILMTQISLIIRGNTDTALRFSKPYSLFAMYYTFSSFLFLEMLS
                     DKLGIKGRGNFLAVFLIVTQVICNFPLVSYRVSTFMKREFPNSGKAWLINIGQFFICY
                     LLAVSLLVIFLFYIQKIRFIHRFIEYFAFDSIEQLTQRWKKRIHWLFVHKSYFLVAAF
                     FYCFTFVQIFVLEPKEGWKETIQVALKIFTQRQAPMILTIIIIMGFFFLLLLISNRFW
                     YALTATLIINLLLTISTVIKMEMREEPVFPSDLKILTGLSELLSMVSPVLLIVGGLIL
                     LLLLITSIIVQRRLQKQYSLKIHWKRRFISIAVLLGCFSGVFFINHKNSPSFLLFNLF
                     KVNKTFFNQQGAVKDNGPVIQFLNNIDIKIMEEPAGYSKEKINGIMKKYNTKADEINQ
                     TRSDWLNNQTIVLNLSESFSDPARVPNLTVPTDPIPYIKSIITEGTGGLMLSVGYGGG
                     TANMEWEGLTGLSISNLSASLVTPYTQLVERQKISPNITDLFDEKIAIHPFTAALYRR
                     KQVFDKFGFDRFYYLDSPDKLTYTDKIEQSPRISDDSAYKETLKALQSNTETSQFIQL
                     STMQNHMPYDDYYSELNYTAEGTAVIPNRRKELQTYMQGLHYTDTAVKKFIQEIDKID
                     KPITFVFYGDHLPAIYSGNDSKKYGLEQHQTDYFIYNNKYSREQAATLNKEVVAPNNF
                     GAMALEHANIKVTPYYALLTEVSNHLPALTIDPTESLSNRFNGKQVFVTEDSQIIQEK
                     NLTEKQKEILEDYRLIQYDLVAGNQYSATWATQK"
BASE COUNT         2786 a         1547 c         1293 g         2799 t
ORIGIN      
        1 aaactaatca gaatcgtaca aatatttaat aaccaaatat atagaacata acttaatatt
       61 aagttatttg aaattccata aaaaacgact gcaggaatta ttgtaagaaa aggataaaaa
      121 tagttcagtc catctccata attgttaaat gttgtatagt tgattggccc ttcaaaaata
      181 gaagataacc ctttgattcg tgaaagatga aaagataaat cacctgttgt ataaatttct
      241 tgagcatttc tcataaaatt tactgaatat aaagtactaa gtaagataag aactactaaa
      301 agaaatgctt ttttacttat tttcatagat ttgttgttct ccttttttaa ttctattttc
      361 agtatactag aattgtcttt ttttaataag ttttgcgtta aatttttcat agcactagta
      421 tgatatacta gaaaagaatc aatttttatt acttttaaat aggagaaaaa aatgaaaaaa
      481 aacaaaaacc aaataataga tatcattttt atgttatttc taagttttgc ttacgtcatc
      541 cctctattca tgtctatggg aatctatcat agtgtcaatc aggatactta ctttcattta
      601 tctcgaatca taggactaga taatgtatgg agttctccag taaacttcaa taacttcgat
      661 catcatggaa caatgatgaa tattttttat ccatggctta ctctttatcc agctttttta
      721 ttttataaaa tgatgggaaa tcttgtttta agttataata tctactattt ttttatcact
      781 tttttaacaa tggtcgtttc ttatttttct atgaaacaaa taaaaaacaa tcgttatatt
      841 tcgctgttat tttcgattat ttatacattt tccgcctatc gtgccattga catattccat
      901 cgtgcttcat tgggagaagc tgtcgcttta acatttttgc ctttgatact aatggggtgt
      961 tacgaaattt atattagaga ttaccaaaaa tggtactggt tgtctattgg catgacgcta
     1021 gtagtgtata ctcatttact ttctgtcgct atggtttctg tatttattgg aggaacgttg
     1081 tttctttctt tttatttttg ggaccaaaaa atcgctagac tcttaagtct tttaaaagct
     1141 accgtcctca cctttttttt aagtgcggga ttcttaattc cttttattca acaatctaga
     1201 gcacaagaat tgaaagtccc actgggaaaa gaattaagtg gtatggctcc tagtgatatg
     1261 ctgacacaca ttttaaataa taactataac aactatacta ttggattatt cttatttctc
     1321 ggattgattg gtgcttttat ttttataaaa aaattaactg ctgatgattt atttattttc
     1381 tttcttggtg tatttgttct tttttgttca accaatttat ttccttggca actttttaac
     1441 catacaccag ttaagagtct acaatttgtc tggcggttaa atggtttttc ttctttattt
     1501 atagcctata cgatgagtat agtgatctat tatatttttt ctactaaaaa taattcatgg
     1561 aaaataatgg tctttacgtt tcttgcacta atattgcatc tctcaggagt aagcaattct
     1621 atccatgcta acaaagattc attaacactt atagcacctg aagacgctgt tgctatagct
     1681 gaaaattaca atcatactga ttatgcaaac aaagagtcaa tctatcatcc tgatatgatt
     1741 aataatgatc aatatttact aggtaaccag gaaataaatc caacaactca ttttatgagt
     1801 aacaaactta caattgaatt agataattcg aataataaaa atactgtctt gacgacacct
     1861 atttatcgtt ataaagggca agtggcttct attaatggca aactagtaca aacaaaatta
     1921 tctaagtttg gcacaactga attaactatt cctccaggta taaataaagt cgttattact
     1981 tatcagtaca caaaactagc aattgcttca agatatttat ctatcgttac tttgatttta
     2041 tttttacttt atcgatttac tttttctaaa caaaaacaac cgagaagaga agtacaacat
     2101 tctcactaga tttttattta agaaagactt tttagctgta cacataaaca ggctaaaaag
     2161 tcttttttta tatttcttta atttgcttca tacattattt aacatcgata tttatactgt
     2221 gaaacatgcg tttcatccat tatcaaagta tttttatcga taataaactt catccaaaaa
     2281 cagaccttgt gcagggacgg tttctcctgc atgttgccgc actttgcttt caaatatttc
     2341 atcgattgtt tctatcggca tggcacctgt gccgatttct agtaatgtcc ccatgataat
     2401 ccgcaccatt ttatataaga atccgtctcc gacaaaagta aaatgaagca tttctccctt
     2461 tcgttcgata gataattcat caatcgtacg cactgtggat ttttttgatt ttttcaatgc
     2521 agaaaaacca atgaaatcat gtgtacccac taatttttcg caagctgcat tcagcttgtc
     2581 catatccaac tcttgaggga aataaaagct gtggtttcgc tcaaatgctg aaggaatcac
     2641 gttgttccaa acataatagc tgtatttttt gcccaccgca ttatatcttg aatggaagcg
     2701 ctcaggcatt tcttcgattc ttttgatgac aatatcccgc ggaaggtaac gattcataaa
     2761 gtcgatcatt tctgccagtc caatttctgt gtttgtttta aaatttgcta cttgtcctcg
     2821 cgcatgggtg ccagcatctg ttcttcctga tccaataatt tctatctctt catttgtcat
     2881 ctgatgcaat actttttcga tttttccttg aatggtttta tcgtcatctc caagtctttg
     2941 ccatcctgaa tatctttttc cgtcatattc gattgtcaac ttgatgtttc tcatatttta
     3001 gtggctcctc tgtcttccat ttggtcttct ctctaccttt ttaagattgt agcacaaaat
     3061 atagctcctt tcttctctaa aacagaagct atacaagaaa actgtggaaa tatatatttc
     3121 agaaaaacaa aaaacagcca ccggatgaag tatccgctga ctgttcaatt tgacggctca
     3181 agttttactg tttgagatgc aagatactca accaggcaat gggcacataa ttaaagaaaa
     3241 aactgattct ttggcaaaaa cctattttat tcagtaatgg ccaagaattt atagaaggaa
     3301 ttcttgccag tccataaatc gccgcaaaaa gcaaactgat cacagacagt ccaaggtata
     3361 agtggcttac gtccatttgc ccattttttc gatagatcaa gaaaagaaga actggaaaca
     3421 ataaaaaacc actgtaacct aaacctgatc cgatattatg gacccatgtc gagacattcc
     3481 acgaagattc atgggtattg atactgaaca aacctgtaaa gatacaatca cctataccat
     3541 agaacgcgat ggctgctgta actagggtag ctaacacacg agatgtactt acaaatgcag
     3601 catacaatgc aggcaatgac aggatgaaaa agatccctga aaccacagac caaataagaa
     3661 acgcttttct tacaggactg gaaacctctc caaatacact gatcacgctc ttcatttgat
     3721 ctaattcagg ataatacaat cctaatacgt acggagtcaa aaaatcactc agcacgccta
     3781 ataataaaaa gaaaaaacca aatttacgta aaaaatccat gatacgcctc caataacaat
     3841 tacctatgct tttaattgtt attataagcg actttatctt gatttaacag aaacctctat
     3901 ttacacgaac atctatataa ctcattaaaa actcgaatca ttttaaaaat actaaatatc
     3961 taacgttcaa cgttcactta atccatctaa acaatctttc aatttgattt tttccccact
     4021 tcttttacgc gcgcctagct ctcctattgc agtaaacaac agatcacttg acgaatttaa
     4081 ggcagtttcc attgaatcct ggataacacc gataataaat ccaataccga cgatttgcat
     4141 cgcgacatca ttagagatac caaacaaact acatgctaat ggaatcaata acagtgaacc
     4201 gcccgcaaca cctgaagctc cacaagcagc taaagcagac aaaatacata aaaggacttt
     4261 caaaacaaaa ggtgcttcaa tccctaaaga atgtacagca gtcaacgtca tcaaggaaat
     4321 ggtaatcgcg gcaccgccca tattgatcgt agcacctaac gggatcgata tggaataaga
     4381 ctcttttgtc aatttcaatc tttcagccaa catcatgttt atcgggatat ttgcggcaga
     4441 acttcgggta aagaaagcgg gaagtgcgct ttctttcaaa caaaagaaaa tcaatggata
     4501 gggattttct ttaataaaca aaaacgtgag gaatgggtac acaactaatg cgacaaacag
     4561 catcgtaccg atcaaaacaa gtaaaagctg cagatactct gccaatccag ctattccagt
     4621 cgtagcaatt gattgataaa ccaatcctaa aatccctatc ggagcaaatg caataatcac
     4681 ttgtacgact tgtgacaacg ctatagatat ctgatccacc aactcttttg tcgattctga
     4741 acgtgctcga aaagctagtc ccaacaatac agcccagaat aagacgccaa ggtaattcgc
     4801 atcaataaga gattgaacag gattttgtgt gacattcgtc aacatagtag ataaaacact
     4861 ttccaaactt tgcggtgctt tttcagatac tgtttcttgt aaagtaatag gaacagtaaa
     4921 aattgaactt acaataactg ctacaagtgc agaaagcaat gttcccacta aatataagat
     4981 caaaataggc ttcacgaatg tcttattccc aattttatgc ttggcaattg acgccatcgt
     5041 caagaaaaaa accagaatag gtgcgattgc cttcaagcaa ctgacaaaca acgttcccaa
     5101 tattgaaata aatgtccatg tggggaaaaa gataccaaac aatattccga ctaaaatacc
     5161 aacaacaata cgttgaacta acgacatatc caaaaacttc tctaacaaat gaccaccctt
     5221 tcacaatttt aacaatcatt gtatcatttt atgcaaagaa actaaaggta taattttcta
     5281 aaaattctaa caatacaaac aaccatttct tgctaatttt gtactttttc tgtctacacg
     5341 ttgttttttg agatattcta agttaggatg ttattaatgg gcaacttatc aggaaacgtt
     5401 ttcttatgtt tttgtccaat ttttttgtga ggtgtttatt cttgaaaaaa ataaagaagg
     5461 agagttatgg cttcctgaca atctttgtcg cttgtataat gatggtttta cagcgtatat
     5521 tgatttcagc agtcactatt cctacatatg caacaaaccc tggtcgattc tacatctata
     5581 catttttaca aacttccgtt gttattggtg caaatttgat cccactttac atgggttacc
     5641 aatatcaaaa aatcgcccgt ttaaaagttt tacattattt aagtcgtttt gcctttatat
     5701 tcctaatagc cacactagtt tgcaatatct tttttttacg tacaagctgg cagcttgaat
     5761 attcgtgatt attggcttat cctaacacct atcagtcaga attactttac ttatgctgtt
     5821 tcttgtactt tgcttttttg tagtattcct tatacagttg gatttttaaa taaattatcg
     5881 aaaacaacaa ttaaatatct actattattt ttaacaattg gattagttgg ctgctctact
     5941 ctatttaata aagacccgtt tgcattacag aatggacaga gtattttatg gattttttat
     6001 ttatttttaa tgggttatgg tttgaaagaa tggaactgga aagaaaaggt ccgctataag
     6061 cttcctcaag tatttatcag cttgattgtt ttattcggtt tgattatttt gatgacacaa
     6121 atttcactca tcatcagagg aaatacagat acagcgctga ggttttctaa accatattct
     6181 ctcttcgcaa tgtattatac tttctcttcg tttttatttt tagaaatgct atctgataaa
     6241 ttaggtataa aaggaagagg aaattttctt gctgtatttt tgattgtcac tcaagttata
     6301 tgtaatttcc ctttagtttc ttatcgcgta tctacattta tgaaacgtga atttccaaac
     6361 tcagggaagg catggctgat aaatatcggg cagtttttta tttgctattt attagcagtg
     6421 tccctcctag ttatcttttt attttatata caaaaaatcc gtttcattca tcgtttcatc
     6481 gaatacttcg cttttgattc gattgaacaa ttaactcagc gttggaaaaa aagaattcat
     6541 tggctttttg ttcataaaag ttatttttta gttgcagcat ttttttactg ctttaccttc
     6601 gtgcagattt tcgttttaga accaaaagaa ggttggaaag aaactatcca ggttgcctta
     6661 aaaatattta ctcagcgaca agcacccatg atcctgacaa tcatcattat tatgggattt
     6721 ttcttcttac tattgttgat ttccaatcgt ttttggtacg ccttgactgc taccttgatc
     6781 attaacttac tgctcactat ttcgacagta atcaaaatgg aaatgcggga agagcctgtc
     6841 tttccttcag atttaaaaat actgaccgga ttgtcagaac tattatcgat ggttagccca
     6901 gtcttattaa tcgtgggcgg attgatcctt ctcctattat tgattactag tattattgta
     6961 caacgtagac tacaaaaaca gtattccttg aagattcatt ggaaacgtcg atttatcagt
     7021 atcgctgtat tattaggatg tttttcgggt gtctttttca ttaatcacaa aaattcgcct
     7081 tctttcttgc tgtttaattt atttaaagta aacaagactt tctttaacca gcaaggcgcc
     7141 gtaaaagata acggaccagt cattcaattc ctaaacaata tcgacattaa aatcatggaa
     7201 gaacctgctg gctattcgaa agaaaaaatt aatggaataa tgaaaaagta caacacaaag
     7261 gcagatgaaa tcaaccaaac aagaagtgac tggttaaaca atcagacgat cgttctcaat
     7321 ttaagtgaaa gcttcagtga tcctgcacgt gtccctaatc tgacagtacc tacagaccct
     7381 attccttaca tcaaaagcat tataacagaa ggaacaggag gattgatgtt atccgtcggt
     7441 tatggtggcg gaacagctaa catggaatgg gaaggactga caggcttgag tatcagtaac
     7501 ctgtctgctt cgttagttac accttatacc cagctagtgg agcgtcagaa aataagtcca
     7561 aatattaccg atctattcga tgaaaaaata gccatccatc cttttacagc tgctctttat
     7621 cgcagaaaac aagtgtttga taaatttggt tttgacaggt tctattattt agacagtccg
     7681 gataaattaa cttatacgga taaaatagaa caaagcccac gcatatcgga tgattcagca
     7741 tacaaagaaa ccttgaaagc tttacaaagc aatacagaaa cgtcacaatt catccaatta
     7801 tccactatgc aaaaccatat gccttatgat gattactata gtgaattgaa ctacactgct
     7861 gaaggaactg ctgtcattcc taatagaaga aaagaattac aaacttatat gcaaggcctt
     7921 cactataccg atacagcagt aaaaaaattc atccaagaaa tcgacaaaat cgataaaccg
     7981 attacctttg ttttttatgg tgaccattta cccgcaatct atagtgggaa tgattcgaaa
     8041 aaatatggat tagaacagca ccagacagat tatttcattt ataacaacaa gtatagtcgt
     8101 gaacaagcag ctacgttaaa taaagaagtt gttgctccta ataactttgg tgctatggct
     8161 cttgagcatg cgaatatcaa agtaactcct tactatgcgt tgttgacaga agtatctaat
     8221 catctacctg cattaacaat tgatcctaca gaaagcttgt ctaatcgttt taatggaaaa
     8281 caggtctttg ttacagagga tagtcaaatt atccaagaaa aaaatttaac tgagaaacaa
     8341 aaagaaattc tagaagatta tcgtctgata caatatgatc ttgttgcagg taaccagtac
     8401 agtgcaacat gggcgacaca aaaaa
//
LOCUS       DAZKKZ010000090         8424 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.092, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000090 DAZKKZ010000000
VERSION     DAZKKZ010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8424)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8424)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8424
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.092"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(248..601)
                     /gene="tnpB"
                     /locus_tag="ACG8LA_002582"
     CDS             complement(248..601)
                     /gene="tnpB"
                     /locus_tag="ACG8LA_002582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="TnpB, as the term is used for proteins encoded by
                     IS66 family insertion elements, is considered an accessory
                     protein, since TnpC, encoded by a neighboring gene, is a
                     DDE family transposase; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HFQ0204850.1"
                     /translation="MLYDLLQTKHIYIVCGKTDLRKGIDGLASLIQQEYQLELYEDAV
                     FLFCGNRQDRFKLLYWDGDGFLLCYKRIENGKLKWPRTKDEVRTLTNQQVRWLLEGLS
                     IDQPRAILPGKKGVF"
     gene            complement(591..785)
                     /locus_tag="ACG8LA_002583"
     CDS             complement(591..785)
                     /locus_tag="ACG8LA_002583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204851.1"
                     /translation="MYKLNEIVPVQLGNEKSAPEKGKPAAAKLAMRIKRENGSEVLIY
                     NGINNYILQAILKELLSNAL"
     gene            868..1476
                     /locus_tag="ACG8LA_002584"
                     /pseudo
     CDS             868..1476
                     /locus_tag="ACG8LA_002584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333159.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1496..2524
                     /locus_tag="ACG8LA_002585"
     CDS             1496..2524
                     /locus_tag="ACG8LA_002585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HFQ0204852.1"
                     /translation="MNRIWNKSHRNNCSLLLILLLGFILWQTPVHASEFNFAVDFELP
                     ANQIDKNKTYINVRMEPGKTQEIPYTVFNRTDKSVTVETLIHSATTNSNGVIEYGESK
                     SKFDETLSYDMKNLAKTVGEITVPPQSAVTETLSLKAPEKELAGVVAGGITFQEKKEN
                     VSNKSTVGVVNQFSQVKAILIRNSEKESSPNLKLKKTYADQSDGRNVIKANLQNPNAS
                     YMFGLTTSVEIYKKETKEPYLSIKKEKIDVAPNTNFDLLVPLEGKKLAPGHYQAVVKG
                     AWKEKRWNLHTDFEITDDAADQLNEKDIDLKNQPETFDWRWLILVGVILIGLFAGLFI
                     LKERRKKK"
     gene            2521..3279
                     /locus_tag="ACG8LA_002586"
     CDS             2521..3279
                     /locus_tag="ACG8LA_002586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HFQ0204853.1"
                     /translation="MKKTIALSTVLAGSLLLCTQSVFAENKSSATTEGTISVTKPDAA
                     NPEDVVPVPPVDPNDPDTPFTPNEPNQGTSGLLTIDQAPDLDFGTIKLGTAKTVYAAL
                     QNGTDSTGTATQVQNFVQVTDKSGIYAGWKLSVKRTEFIGTTSDTNKLTGSKVKFKNA
                     VIRNSATNSSGTPSTISGTGAEGIEIPADQAVDLVTAGANEGIGTWIYSLGENVEQGR
                     QSVELFVPVSNYAVDNYVSTFTWSLTDAPTEGKA"
     gene            complement(3365..4105)
                     /locus_tag="ACG8LA_002587"
     CDS             complement(3365..4105)
                     /locus_tag="ACG8LA_002587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytR/AlgR family response regulator
                     transcription factor"
                     /protein_id="HFQ0204854.1"
                     /translation="MKKYFIIEDNQFHSEWIIKELVNHHIENIVQLTSISQINQLIQL
                     GTIDNHDVFFIDIDLKQSLTGIDVAEQIRKKNAHSNIVFFTAYTNFAVEIINRKILPI
                     GYIRKDRNLSEQIRQVLEQINWKEQQIVNVDKIFIDQKGGSLVLYPREILYIESIKGL
                     KNQVMVKTTTEDKLVNTSLKQLKTELEKYAYFLLLKSYCINLSQLQKIDSAHYVLEFF
                     NGDSLLVGRKIFEKTKERFHDFQKTASS"
     gene            4166..5419
                     /locus_tag="ACG8LA_002588"
     CDS             4166..5419
                     /locus_tag="ACG8LA_002588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HFQ0204855.1"
                     /translation="MVATVTLYLTFTLILDLGIYLFFSKQLLVKNSFGFIALMVVTLL
                     FPIPKVSFPYLVGLLLMFLFYFTTKNLFISCLISNLFFAITGLSFFLVFDLMDYLGKR
                     HLGTASFFALLIAFIFYLLVKSIDKQTRFLNLLFTYPTEHYFGGICILLSWGVIYLVL
                     GSVHFRSSNYLLLSLLSIVISFFSLFFSIMLISFQVKERQHQESLQLYQINEEYYHHL
                     EEFKHDYKSLLFSLKITLQENKKETLEFLEILEDHSAAIFEKPQIQQLTNIVSPAVRG
                     VFLKFLEKAESEKIPIQVVIPVEVKTIPIDLVVFIRCLSIFISNAFDHRVADQSPITI
                     NLLEEKEGLRFSIANKANPTNLTLSEMVKRGKTSKKNGGLGLYSAKKMLDVYENAELK
                     IEFSKQNHYFFVEMYLASRKSKSAY"
     gene            5714..5968
                     /locus_tag="ACG8LA_002589"
                     /pseudo
     CDS             5714..5968
                     /locus_tag="ACG8LA_002589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308281.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
     gene            6090..6416
                     /locus_tag="ACG8LA_002590"
     CDS             6090..6416
                     /locus_tag="ACG8LA_002590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HFQ0204856.1"
                     /translation="MNSMEKVNQFRDERNWRQFHNEKDLAISISLEASELLELFQWKT
                     PEEVKETQLERIKEELADVLIYSYMMADNLQLDLDEIIEEKLIKNNLKYPVEKSAGVR
                     KKYTEF"
     gene            6484..7197
                     /locus_tag="ACG8LA_002591"
     CDS             6484..7197
                     /locus_tag="ACG8LA_002591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HFQ0204857.1"
                     /translation="MKKKGKAKRWLVNILLFLLLLVGLALIFNEQIKDYLVRETGDKY
                     AIANVTKEDLKKNNDKDVSFDFDAVEPMTTEGVMRSQMRGTDLPVIASIAVPSVSINL
                     PIFKGLDNTSLLYGAGTLSPDQEMGKGNYALASHRATNPELLFTPLENLEMGAKIYLT
                     DLENVYTYKTFFKEKVAPTDTQLLNEVEEKEIVTLITCGDMDAVTRLVVQGELESVTP
                     IKDATDDMRSAFNLETKTF"
     gene            7507..8359
                     /gene="licT"
                     /locus_tag="ACG8LA_002592"
                     /pseudo
     CDS             7507..8359
                     /gene="licT"
                     /locus_tag="ACG8LA_002592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338530.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator LicT"
BASE COUNT         2892 a         1428 c         1664 g         2440 t
ORIGIN      
        1 cgtccaaata atttgttggt taaataattg accttttcat tcaatagttg gatttcagtt
       61 gtaagattct gaatggtttg ttgttgtgct tgattggttt tatgggcttc ttgaagcaac
      121 tgaagcaacg tatctgtagt ttccaaaatt tttcaccacc ttgaatcgaa ctgattttgt
      181 tacagaatac cacaagaaac gcacaagaaa taggggttca acacattttt tgtgttaacc
      241 ccccagctta aaaaactcct ttttttcctg gcaaaatagc tcgaggttga tcgatactta
      301 atccttctaa caaccatcga acctgttggt tcgttaaggt tcgaacttcg tctttcgtcc
      361 gaggccattt taacttgccg ttttctatcc gcttataaca gagaagaaaa ccatcaccgt
      421 cccaatagag aagtttgaaa cggtcttgac ggttcccgca aaataaaaaa acggcatctt
      481 cgtaaagctc gagttgatac tcttgttgaa taagactggc aagaccatca attccttttc
      541 gcaaatctgt ttttccgcac acaatataaa tatgtttggt ttgaagtaaa tcataaagca
      601 ttggacaaca gttctttcaa aatagcttga agaatataat tgttaatacc gttatagatc
      661 aaaacttcag aaccattctc tcttttgatg cgcatcgcta acttggcagc cgcgggttta
      721 cctttttctg gtgcactctt ttcgtttcct aattggacag gaacaatctc atttaattta
      781 tacatagaaa acctccagac ttcttgatag ctcaagtata tcttgaggtg catttgttag
      841 taaggtactg ttctatgggg cgcttaccca gaaaatcaac tttttgcagg agatgtatta
      901 gaaattgtat taaacgacca agcaggagaa gctgctgcta agggtgtgca gaacaagcca
      961 agtaccaacg atgaaattgg gaatcacaat ccaagtgata cgccagttgt ttatcatgat
     1021 gccccgcctt ttgcacctgc tacgaagatt gtagtagaag gtggtctctc atttcttgcc
     1081 ccttccaaac tcgattgtgg tcagatcaaa gcaactgggt tgacgcaaga agcatttggc
     1141 caaatggata tacaggaaaa attatggatt tatgatcagc gagaaacaaa aagtccatgg
     1201 atcttaacga taaaattatc tcagcctttc acaaccgatg caggattttc tatgcaggat
     1261 gtcctatatt tcaagaaagc tgaggagtat caattagtga atgaagaaga actggaaatt
     1321 gtcagaggac aaaattcaac gaatgtgcaa acagattatt cagaatattt aaataatggt
     1381 cgggcgttta aacttgtctt aaccaaagaa aatcagatag ctggtaatta ctcagcagag
     1441 atgacatgga cattagcaga tgcgccgaca gaataaagat caaggagaat gattgatgaa
     1501 tcgaatatgg aataaaagtc atcgaaacaa ctgctcttta cttctgatcc ttctccttgg
     1561 attcatcctt tggcagacac ctgtccatgc ctccgaattc aattttgcgg tagattttga
     1621 attaccggct aatcagattg ataagaacaa aacatatata aatgtaagga tggagcctgg
     1681 gaaaacacag gaaatcccct acacggtctt taaccgaaca gataaatcag taacagttga
     1741 gacattgatc cactccgcta cgacgaattc aaacggtgtg atcgaatatg gagaatcaaa
     1801 aagtaaattt gatgaaacat taagttatga tatgaaaaac ttagcaaaaa cagtgggaga
     1861 aataactgtc cctcctcaaa gtgcggtcac tgagacactt tcactgaaag ctccagaaaa
     1921 agagctggct ggtgtggtcg caggaggaat cacgtttcaa gaaaaaaaag agaacgtttc
     1981 taacaaaagt acagttggtg tcgtcaatca gttttctcaa gtgaaagcaa tcttgattcg
     2041 aaatagcgaa aaagagtctt ccccaaattt gaaattaaaa aaaacttatg cggatcaaag
     2101 cgatggaaga aatgtgatta aggcgaatct tcaaaatcca aatgcttctt atatgttcgg
     2161 cttgactaca tcggttgaaa tctacaaaaa agaaacaaaa gagccttatc tttcaataaa
     2221 aaaagaaaaa atagatgtag cacccaatac aaattttgat ttacttgtcc cattagaagg
     2281 aaaaaaatta gctccgggac attatcaagc ggttgtgaag ggtgcttgga aagaaaaacg
     2341 ctggaatctc cataccgatt ttgaaataac tgatgatgca gcggaccaat tgaatgaaaa
     2401 ggatattgat ttaaaaaatc agccagaaac atttgactgg cgatggctga tacttgttgg
     2461 agtcattctt attggcttat ttgctggatt atttatttta aaagaaagaa ggaaaaagaa
     2521 atgaaaaaaa caattgcatt aagtaccgtt ctagctggaa gtctattatt atgtacacaa
     2581 agtgtttttg ctgagaataa gagctcagcc actacagaag gaacgatttc tgtaacaaaa
     2641 ccagatgccg caaatcctga agacgttgtt ccagttcctc ctgttgatcc aaatgatccc
     2701 gatacgccgt ttacacctaa cgaaccaaat cagggaacat ccggattact gacgattgac
     2761 caagctccag atcttgattt tggaacaatc aagttaggta cagcaaaaac agtatatgct
     2821 gcattacaaa acggaacgga cagtacaggg acagcaacac aagtacagaa tttcgtacaa
     2881 gtaacggata aaagcggaat ttatgccggt tggaaactat cagtcaaacg aacagaattt
     2941 attggtacaa catctgatac gaataaacta actggttcaa aggtgaaatt caaaaacgcc
     3001 gtgattcgaa atagcgcaac taatagcagt ggaacgccat ctactatttc tggtactggc
     3061 gctgaaggaa ttgagatccc agcagatcag gcagtagatc tagtaactgc aggagcaaat
     3121 gaagggattg gcacatggat ttattcatta ggagagaatg tggaacaagg gagacaatca
     3181 gtggaattat ttgttcctgt atccaattat gccgtagaca actacgtttc aacattcaca
     3241 tggtcgttaa cagatgctcc tacagaaggg aaagcgtaaa atcaaatcaa tgacttcagg
     3301 gagtggagcc gattcaaggc caactccctg aaatctgcta tgcttacgtc tcagctctta
     3361 ttcatcaact cgaagcagtt ttttggaagt catggaaacg ttcctttgtc ttttcaaaga
     3421 tctttcgacc aacgagtaag gagtcaccat tgaaaaattc taacacataa tgagcagaat
     3481 caattttctg caattgcgat aagttgatac agtaagattt taatagtaaa aagtaagcat
     3541 acttttccaa ctctgtcttc aattgtttta aagaagtatt cactaattta tcttctgtag
     3601 ttgttttgac cataacttgg tttttcaaac ctttgatact ttcaatatat aaaatttccc
     3661 gaggatacag gacgagactt ccaccttttt gatcaataaa gattttatcg acatttacga
     3721 tttgctgttc tttccaattg atctgttcta gcacttgacg aatttgttca gataaattcc
     3781 tgtcttttct gatatatcca atcggaagga ttttccgatt gatgatctct actgcaaaat
     3841 tcgtataagc ggtgaaaaaa acaatattac tatgtgcatt ttttttacgt atttgttcgg
     3901 cgacatcaat acctgtgagt gattgcttca agtcgatatc gataaagaaa acatcgtgat
     3961 tatcaatagt acccaactgg atcaactgat tgatttgaga gatagaagtg agctgcacga
     4021 tattctcgat atgatgattg accaattctt tgatgatcca ttcgctgtga aactggttat
     4081 cttctatgat aaaatacttt ttcatatgca ggctcctatt aaaaaaatat gtgtacattt
     4141 tgaaacaaaa caatggagga ataagatggt cgcaacagtg acactttatt tgacctttac
     4201 tttgatttta gatttaggta tctatttatt cttttcgaaa caactgctag taaaaaacag
     4261 ctttggtttt atagctttga tggtggtgac acttttattt cctatcccta aagtgagctt
     4321 tccttaccta gttggcttat tattgatgtt tcttttttat tttactacga aaaacctgtt
     4381 tatcagctgt ttgatcagta atcttttttt tgctatcact ggactcagct tttttctggt
     4441 ttttgatctg atggattatt taggaaagag acatcttgga acagcaagtt tttttgcact
     4501 acttatcgca tttattttct atctattagt aaaaagtata gacaaacaga cgagatttct
     4561 caacttgctt tttacttatc caactgaaca ctattttgga ggtatttgta ttttattaag
     4621 ctggggcgtg atttacttgg tattgggaag tgttcacttc cgctcatcta attatctgct
     4681 tctatctctt ttgtcgatag tcatcagttt tttttctttg tttttttcca ttatgttgat
     4741 cagtttccaa gtaaaagaaa gacaacatca ggaatcgctt caactgtatc aaataaatga
     4801 agaatattac catcatctag aggaattcaa acatgattat aaaagtctac tgttttcatt
     4861 aaaaattact cttcaggaaa ataaaaaaga aacgttggaa tttttagaaa tcttagaaga
     4921 tcattctgca gctatttttg aaaaaccgca aatacaacag ctaacaaata ttgtatcccc
     4981 agctgtcagg ggtgtctttt taaaatttct agaaaaagca gaatcggaga aaatcccgat
     5041 ccaagtagtt attcctgtcg aagtgaaaac aatcccgatt gatctggttg tttttattcg
     5101 ctgtttatct atttttattt ctaacgcatt cgatcatcgt gtagccgatc agagtccgat
     5161 tacgatcaat ctgctggaag aaaaagaggg attacgtttt agtatagcga acaaggcaaa
     5221 tccgacgaat ttgacgctat cggagatggt caaaagagga aaaacctcta aaaaaaatgg
     5281 cgggttaggt ctatacagtg cgaaaaaaat gttggatgtt tacgaaaatg cagaactaaa
     5341 aatcgaattt tcaaaacaga atcactattt ttttgtagaa atgtatctgg catctagaaa
     5401 gagcaaatca gcctactgac ttactgtcaa aggataagct tgaggaaagt ctacacggag
     5461 atagagacaa caacacagca tattcaaaag aaacagaagc gtgatgaccg ttgtcaccct
     5521 tctgtttctt ttgctatgta gttaaacaaa gtagttgaca cttccgctac ttagtattag
     5581 tacgaaagta tacttcatga tactaagtag ataagaagtg aaaagcggaa cccacgatcg
     5641 tcaaaatgct aactgctttg cttacaccag ataaagggaa gagcaatatc gcttatttta
     5701 ggcgtggaga agcaagaaaa tccctacgat cacacaaaaa atgctgaccc agcagttaag
     5761 agagttagaa caagatggca ttgtccatcg aaaagtctat aaccaagtcc cgcctaaagt
     5821 agagtactcg ctcaccgaag aaggaaaatc attaagagag attctagtag cgatgtctgt
     5881 ttggggagaa gaacgtatcg aaaaacaaaa agcctcaggg gaagaagtca cattactgca
     5941 tacacatggt ggctacctaa attactgatt tctatgacat ttattttaaa taaaagaaaa
     6001 caggagtttt tttaaaagca tcatctattt tttatgtaaa aaaatggtat gattaatcaa
     6061 gtaagaaatg attggaagaa ggcaagcaaa tgaatagcat ggaaaaagtt aaccagttta
     6121 gagatgaacg taattggcga caatttcata acgaaaaaga tttggctatt tctatttctt
     6181 tggaagcatc tgaattgtta gaactttttc aatggaaaac gccggaagaa gtaaaagaaa
     6241 cacaattaga acgaatcaaa gaagaactgg cggatgtatt gatctattca tacatgatgg
     6301 cagacaacct tcagctggat ctagatgaga tcattgaaga aaaattgatc aaaaataatt
     6361 tgaaatatcc tgtagaaaaa agcgcaggtg tacgaaaaaa atacacagag ttttagaaat
     6421 gtgtcattcg gctgttggaa agagcaaaag aaaaacagta aaatgagtct ggagggagag
     6481 aaaatgaaaa aaaaaggaaa agcaaaaaga tggctagtca atatcctctt gttcctcttg
     6541 ttattagtag gactagcttt gattttcaat gaacagatca aggattatct tgtcagagag
     6601 acaggagata aatatgctat agcgaatgta acaaaagaag atctgaaaaa gaataacgat
     6661 aaagatgtca gttttgactt tgatgcggta gaaccaatga cgacagaagg ggtcatgagg
     6721 tcgcagatga gaggaacaga tctaccagtg attgctagta tcgcagtccc ttcagtttca
     6781 atcaatttac cgattttcaa aggcttggat aatacgtcac tactttacgg agcaggaaca
     6841 ttatctccag atcaagaaat gggaaaagga aattatgcct tagcaagcca tcgtgcaacg
     6901 aaccctgaat tgttgtttac accgctggaa aatttagaga tgggtgccaa gatctatttg
     6961 acagatttag aaaatgtgta tacatacaaa acatttttta aagaaaaagt tgctcctaca
     7021 gatacccaat tactgaatga agtcgaggaa aaagaaattg tcacactaat tacttgtggc
     7081 gacatggacg ccgtcacgcg actagttgta caaggagaac tggaaagtgt tacaccgata
     7141 aaagatgcga cagatgatat gagatctgct ttcaatctag agacaaaaac attttaggat
     7201 actgggacat aagtcgttac agattaaaaa cagccaaagg atatgaatcg ataaggaaaa
     7261 accaatttgc tgaaaaaaag aggaacgcaa agaggtgcat ctctgatttg gttgttttct
     7321 agatagactt gtgttccagt ttttttattt tttatatgaa aaggcttgca taaataaaaa
     7381 ttcgatggta tgatgatttt gaataagaaa tggattgtta ctgtacggca ggcaaaacca
     7441 gaattcagct aagaaacagt aggcgaattc taggtttttt tatttttctt gagagggcga
     7501 agcaaaatga aaattgataa aattttgaat aacaatgtcg tcatttcgaa aaatggattc
     7561 ggggaagaag tcgtttgtat gggaaaagga ctagcttttc aaaaaaaaga ttggggacga
     7621 gatttcgcca gaagcggtcc aaaaagaatt tattttaaga gattcttttg ctaaaaacca
     7681 attccagcag ctgatggctg atattccggc agaggagatc gaatgggtca aacaagtagt
     7741 cgaactggct gaagataaac taaaagttga attttcgcct aatatttatc tgacattgac
     7801 cgatcatctt cattatgcga tcacacgagc aaaagaaaat atccaactgc ctaatccatt
     7861 attatttgaa acaaaaaaat tttatccgaa agaatatcaa gcagcgaaag aggctctttt
     7921 gttcgtgaaa caaaagacgg gtgtggaact ttctgaggat gaagccggtt ttattgcctt
     7981 tcattttgtg aatagccaac aaggaaacga agacatgcaa gtgacgatga ccgctaccac
     8041 aatggtaaga gatatactga gtatcatcag taaattcttc ggcatcgtgt tcgatgaaga
     8101 atctttgaat tatcagcgta tcattactca tctgcagttt tttgcccagc gttatctcaa
     8161 aggggaagga tctgacgagc aagatgaatt tctctacgca ttagttcaag gaaagtatcc
     8221 aaaagcgttt cattgtgtcg aacggatcaa tgagtatctt cgacaaacgc aaaaacagga
     8281 aatggggatc gcagagcaga tttatttaac gattcatatt caaagagtag taagtgagaa
     8341 aaaaagcatc caatcataag gattgttact gtatggcagg caaaacctgg attgaaaaaa
     8401 taggttcacg aatgtttgtg actg
//
LOCUS       DAZKKZ010000091         8354 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.093, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000091 DAZKKZ010000000
VERSION     DAZKKZ010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8354)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8354)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8354
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.093"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..552
                     /locus_tag="ACG8LA_002593"
     CDS             <1..552
                     /locus_tag="ACG8LA_002593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204858.1"
                     /translation="IKKIPKIDENSKLMKNIQSIFGIEEVFVGDKCIFFDQPLLSDGY
                     GIDETDIFAKVNSIFSGKKETLIKLHPRARTNRYGEKNILNSSLPFEVLLLENDFSST
                     LLISPISTISFSPSMMFEKTINSIMLAKLILNEYTALSEDKKETLTNIVLFCEHYNRL
                     SEEKILLPENWAELRKLVEYGII"
     gene            539..1960
                     /locus_tag="ACG8LA_002594"
     CDS             539..1960
                     /locus_tag="ACG8LA_002594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HFQ0204859.1"
                     /translation="MGLFNTLSKSKLVKSSFWYTIGNFFIKGISFITIPIFVNITTQA
                     EYGLINNFTSFVSIFSILVGLSLNSAINNASFDYKDDINEFMSSVLSLATLSLIVFLL
                     IGNIYFLFSNAFFDMNQLVFNLMLLQSFASFVISYIQSYFTINFNHFKYLILSFISTF
                     LNIAISVALMQTLYFDDKYVGRVVGGTLSFVLIGLVIYLRIMIKGAHFFDKKQWRYAL
                     KISLPLIPHSLANIVLAQFDRIMINSYLGPAAGGIYSYISNIGIILSVIWMSTNNAWV
                     PWFYGEMSKNNEKKVKKVSNYYLVVFTLITMIVMVVSIDLAKFMAPKDYYSGLSLVVP
                     ITLGYFFQFLYSLPVNAEFYEKKTSFIAIGTVASAIVNILLNMIFIPRLGIIAAGYTT
                     VFTYFLLFIFHYNIAKKITNKQLFDTKKICIIIIFVSIFSLILHILINQMLIRYVLTS
                     LLIISLVIYFLKIKNRIIDDYNS"
     gene            1973..2980
                     /locus_tag="ACG8LA_002595"
     CDS             1973..2980
                     /locus_tag="ACG8LA_002595"
                     /EC_number="4.2.1.115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050377 - UDP-glucose 4,6-dehydratase
                     activity [Evidence IEA];
                     GO_function: GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 4,6-dehydratase family
                     protein"
                     /protein_id="HFQ0204860.1"
                     /translation="MFKGKTILVTGGTGSIGSEIVRQLLKYEPKAIRIYSRGEEKQFY
                     MQQELSNHTNLRFLIGDIRDSQRIDYACRDVDIIFHAAAMKHVPASEYNPMEAVKTNV
                     MGTQNVIDAAIKNNVKHFVGISTDKVVSPTNTMGATKLLSEKLIIAANQYKGKTETIF
                     SCVRFGNVMGSSGSVIPLFSKQIKNNKDITLTDVDMTRFMMSIPDAARLVLSAAMNSK
                     FGETYVLKMPAINILTLAQSLIKIYNDTHDEKYRGEIKVVGIRPGEKLYEELMTTDEI
                     ERSYENDKMYIIPPHYHATDELYKDYEKIKITAYSSDATELMSGQEFIRIAKENNVVT
                     W"
     gene            2992..3996
                     /gene="neuB"
                     /locus_tag="ACG8LA_002596"
     CDS             2992..3996
                     /gene="neuB"
                     /locus_tag="ACG8LA_002596"
                     /EC_number="2.5.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0016051 - carbohydrate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate synthase"
                     /protein_id="HFQ0204861.1"
                     /translation="MKSEVYVIAEIGVNHNGSLDLALESIDKAKECGANAVKFQTFKT
                     NKLVSKKAPMAKYQKDNLKEDSSQFEMLKKLELSQSDFIRIKDYCIQNKIDFLSTPFD
                     EESADFLKQIGVQGFKIGSGDLTNLPFLRKIDMYGLPVLLSTGMADIHEVSEAVDCFI
                     DSPVTILHCTSNYPASSEDINLLAINTLKEMFGIPVGYSDHSLGYDVGICAVAMGAKV
                     IEKHFTLDKELPGPDHKASLDPQEFADFVKHIRNTEIFLGDGVKRAMPSELSTKEVSR
                     KSLVVTENLNVGDILTEKSLTIKRPGNGIAPKFLYQYIGKKVKRPISADSVLLEEDVE
                     "
     gene            3993..5141
                     /gene="neuC"
                     /locus_tag="ACG8LA_002597"
     CDS             3993..5141
                     /gene="neuC"
                     /locus_tag="ACG8LA_002597"
                     /EC_number="3.2.1.183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008761 - UDP-N-acetylglucosamine
                     2-epimerase activity [Evidence IEA];
                     GO_process: GO:0006047 - UDP-N-acetylglucosamine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase"
                     /protein_id="HFQ0204862.1"
                     /translation="MKKILIVSGTRADYGIYKPVAENLLQDNWDVSFVVSGMHLSHKY
                     GFTKELILADGFRISGEVQSLFLENNKGNMARSVALEINGFTNIFEQTSPDFVLLLGD
                     RGEMLAAAIACLYLGIKTAHIHGGEVSGTVDESIRHAITKIASVHFAATEKSKERLIK
                     MGEDSWRVFPVGAPRIDTILNNRLPSFRDIKEKYHLKFEKKKYVLQVFHPVVTELENI
                     EKQILALINSMEQQSQPIICILPNSDAGSEIIRKMYQKYLKTDIIYITNLEPEEYLTI
                     LKECKFMIGNSSSGIIEAASFKIPVINLGTRQNGREQSKNIINANLNENEIETALNKI
                     QDPQFIKSLKNVKNIYGDGNSSRRITKTLNQILNDGEDIKWIQKQIAY"
     gene            5114..5791
                     /locus_tag="ACG8LA_002598"
     CDS             5114..5791
                     /locus_tag="ACG8LA_002598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HFQ0204863.1"
                     /translation="MDSKTNSLLKYTSDPYIIIGAGGHAKVIIETLRLENKLIYGFFD
                     DKQNKMQDLKYLGKINELNSWADSKKKIYKFIVAIGDCVVRKKIIKKLNMPSEQYGIA
                     VHPSAIVAKEISIGYGTVIFANAVINPDAVIGEHAIINTGSIVEHDCRINNYVHLSPG
                     VCLAGGVHVGVGTQIGIGSQCIQMKKIGSWCMIGAGSTIVKDIPSHSLAYGNPAKIKK
                     EGINFEF"
     gene            5742..6923
                     /locus_tag="ACG8LA_002599"
     CDS             5742..6923
                     /locus_tag="ACG8LA_002599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HFQ0204864.1"
                     /translation="MAIQLKLRKKELILNSRILLSSPHMGGTEEKYVAKAFKDNWIAP
                     LGENVDKFEESITKYTGSKGGASALSSGTAAIHLALRLLNVGKNDIVFAPSFTFIATV
                     NPILYQGAVPVFIDSEPNTWNMSPVALESALEEAERNNQLPKAIIVVNLYGQMADYER
                     ILAIANQFNVPVIEDAAESLGSTYKGISSGLFGTIGIYSFNGNKIITTSGGGALVSSD
                     KKYVEHSRFLATQARDQAPYYQHSEIGYNYRLSNISAGIGRGQMEVLNDRVAKRREIF
                     NRYKEAFSGIDRIEMMPEVDGMVPNRWLSTLTINDYNSIDQVVNVINKLNEKNIETRA
                     LWKPLHLQPVFQGVKMYYHDNNLSVSEKLFNSGLCLPSGSNMTDSEQEFVIDEFKKIF
                     K"
     gene            6936..7913
                     /locus_tag="ACG8LA_002600"
     CDS             6936..7913
                     /locus_tag="ACG8LA_002600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFQ0204865.1"
                     /translation="MNIGIIGLGSMGKRRLRLIQEHFNDILLCGVDTNEARRKEVEKE
                     FGIPTYNSLTEAKNLFEINSVFVCTSPITHEFIIKEALNLDCNIFTEINLLNEYYDEI
                     IEVAKKKDRLLYLSSTFLKRKEIQYIKSKVTHNKKISYQYHVGQYLPDWHPWEDYRNF
                     FVSNKKTNGCREIFAIELPWIIDTFGKVKSFTVMTQKLSNLDIDYSDSFTLIIEHETG
                     IVGTLSVDVVSRVAKRNLTIIGEKILIEWEGNPDSLFSWNEETSSMTDIQLYDEVMHD
                     NNYSHTIIEDAYLEEIKEFFTLLEKKMEPQYTFEKDKYIINLINDIEVN"
     gene            7913..>8354
                     /locus_tag="ACG8LA_002601"
     CDS             7913..>8354
                     /locus_tag="ACG8LA_002601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HFQ0204866.1"
                     /translation="MMKVIFFGLGSIGKRHLKNLISYGKKNSINFDITAYSSSGKKEF
                     EEITYIQNRDDLDTHYDIAFITNPTFKHLETLNVIVEKVDYIFLEKPAFSESIDLTQY
                     NYDYKNIYVAAPLRYKNIMEVVRNSIQSKKVYSVRAICSTYLPDW"
BASE COUNT         3038 a         1053 c         1521 g         2742 t
ORIGIN      
        1 ataaaaaaaa ttcccaaaat agatgaaaac agtaaattga tgaaaaacat acaatcaatc
       61 tttgggatag aagaagtttt tgtcggagat aaatgtatct tttttgatca acctttatta
      121 tctgatggtt atggcataga tgaaacagat attttcgcta aagtaaatag tatattttct
      181 ggaaaaaaag aaactttaat taagcttcat cctagagcaa ggacaaatcg ttatggtgaa
      241 aaaaacatat tgaattccag tttaccgttt gaagtcttgc tacttgaaaa tgacttctct
      301 tcaacacttt tgattagtcc tatatctaca atttcttttt caccatctat gatgtttgaa
      361 aagacgatca actctattat gttggctaaa ttaattttaa atgaatatac agcattatct
      421 gaagataaaa aagaaacatt gacaaatatt gttcttttct gtgaacatta taaccgtcta
      481 tcagaagaaa aaattttact cccagaaaac tgggcagaat taagaaagtt ggtagagtat
      541 gggattattt aacacacttt ccaagtcaaa attagttaag tccagtttct ggtatactat
      601 agggaatttt tttattaagg gaatttcatt cataactatt cctatttttg taaatattac
      661 tactcaagca gaatatggtt tgattaataa tttcacttca tttgtatcaa ttttttcgat
      721 tcttgttggg ctaagcctaa attcggcaat taataatgca agttttgact ataaagatga
      781 cataaatgaa tttatgtcat cggtactttc tctagctaca ctttcgttaa ttgtgttctt
      841 attaataggg aacatatatt ttttgttttc aaatgctttt tttgatatga accaacttgt
      901 atttaatttg atgttattac aaagttttgc tagttttgta attagttata tccagtctta
      961 ttttacgatt aactttaacc attttaaata tttgatttta tcttttatat ctactttttt
     1021 gaatattgca atctctgtag ctttgatgca gacattatat tttgatgata aatatgttgg
     1081 cagagtagtc ggcggaacac tgtcatttgt gttgataggt ttagtaattt atttaagaat
     1141 aatgataaag ggtgctcatt tttttgataa aaaacagtgg agatacgctt taaaaatctc
     1201 tttgccgcta atcccacatt ccttagcaaa tatagtttta gcacaattcg atagaattat
     1261 gattaattct tatttaggtc ctgctgcggg gggaatatat tcctacatta gtaacatagg
     1321 tattattcta agcgtaatat ggatgtctac taataacgcc tgggttccat ggttctatgg
     1381 tgagatgagt aaaaataatg aaaaaaaagt gaagaaagtt agtaactatt atttagtagt
     1441 ctttactttg attacgatga ttgtaatggt agtttcgatt gatttagcaa aatttatggc
     1501 tccgaaagac tattattctg ggttatcttt agtggttccg ataaccttag gctatttctt
     1561 tcagttttta tatagtttac cagttaatgc tgaattttat gagaaaaaaa catcgtttat
     1621 tgcgattggt acagtagcaa gtgctatagt taatatacta ttaaacatga ttttcatacc
     1681 taggttagga ataattgctg ctggatacac aaccgtattt acgtattttt tactttttat
     1741 ttttcattat aatatcgcta aaaaaattac gaataaacaa ttatttgaca caaaaaaaat
     1801 atgtatcata ataatttttg tatcaatttt ttctttgata cttcatattt taatcaatca
     1861 aatgttgatt cgttacgttt tgacatcatt attgataatt agtttagtta tatatttttt
     1921 aaagattaag aatcgaatta tagatgacta taattcatag gaggagatat aagtgtttaa
     1981 aggaaaaaca atattagtaa ctggcggaac tggttccatt ggaagtgaaa ttgttcgtca
     2041 gcttttaaaa tatgaaccaa aagctatcag aatttatagt agaggtgaag aaaaacaatt
     2101 ttatatgcaa caagagctct caaatcacac taatttgaga tttttaattg gtgatatcag
     2161 agactctcaa aggattgatt atgcatgtcg tgatgtggat attatttttc atgctgccgc
     2221 aatgaaacac gttccagcaa gtgaatataa tcctatggaa gctgtaaaaa caaatgtgat
     2281 gggaactcaa aatgtaatag atgcagcgat caaaaataat gtaaaacatt ttgtaggtat
     2341 cagtacagat aaagtagtga gtcctactaa caccatgggt gcgacaaagt tattgagtga
     2401 aaaattaata atagctgcca atcagtataa aggaaaaaca gaaacaatat tttcttgtgt
     2461 aaggtttgga aatgtcatgg ggtcaagtgg atctgttatt cctcttttta gtaaacaaat
     2521 aaaaaacaat aaagatatta ctttgacaga tgttgatatg acacgattta tgatgtcaat
     2581 accggatgct gcaagattag ttctgtctgc tgctatgaat tcaaaatttg gagaaacata
     2641 tgtcttaaaa atgccggcaa tcaatatttt aactttagct caatcattaa taaaaatata
     2701 taatgataca catgatgaaa aatatagagg tgaaataaaa gttgtaggta tcaggccagg
     2761 agaaaaatta tatgaagagc taatgactac agacgaaatt gaacgctcat atgaaaatga
     2821 taaaatgtat atcattccac cacactatca tgctactgac gaactgtaca aagattatga
     2881 aaaaattaaa atcactgcat actcttcaga tgcaacagaa ttaatgagtg gacaggaatt
     2941 tattagaatc gcaaaagaga ataatgtcgt gacttggtaa ggagttttat gatgaaatca
     3001 gaagtatatg taattgcaga aattggtgta aaccataatg gaagtctaga tttagcttta
     3061 gaaagtattg ataaagctaa agaatgtgga gctaacgcgg ttaaatttca aacatttaaa
     3121 acgaataagc tagtttccaa aaaggctcca atggcaaaat atcagaagga taatcttaaa
     3181 gaggacagtt ctcaatttga aatgctaaaa aaattagaat tatctcaatc tgattttatt
     3241 agaataaaag attattgtat acaaaataaa attgattttt tgtctactcc ttttgatgaa
     3301 gaaagtgcag actttctaaa acaaattggt gtacaaggat ttaaaattgg ctcaggagat
     3361 ttaacaaatt taccttttct tagaaaaata gatatgtatg ggttgccagt tttattatct
     3421 acaggtatgg ctgatattca tgaggtcagt gaggctgtag attgtttcat agatagtcca
     3481 gttactattt tacattgtac ttcaaattat ccggctagtt ctgaagatat taatttattg
     3541 gcgattaaca cattaaaaga aatgttcggg atacccgttg ggtactccga tcattcattg
     3601 ggatatgatg ttggtatttg tgctgttgcg atgggtgcta aggtaattga gaaacatttt
     3661 accttggata aggaactacc tggtccagat cataaagctt ctttagatcc tcaggaattt
     3721 gcagattttg taaagcatat tagaaacact gaaatatttt taggtgatgg tgttaagcga
     3781 gcaatgcctt ctgaacttag tacaaaagaa gtatcaagaa aaagcctagt ggtcactgag
     3841 aatttaaatg tgggagatat tcttacagag aaatctctta caataaaacg tcctggaaat
     3901 ggaatagctc ctaagttttt atatcaatat attggcaaaa aagttaaaag accaataagt
     3961 gcagatagtg ttctgcttga ggaagatgtt gaatgaaaaa aatacttata gtaagtggaa
     4021 cacgagctga ttatggaata tataaacctg ttgctgagaa tttactacaa gataattggg
     4081 atgtatcatt tgttgtttct ggaatgcatt tatcccataa atatggattt actaaagaat
     4141 tgatcttagc tgacggattt agaattagtg gagaagttca aagtttgttt ttagagaaca
     4201 ataagggaaa catggctcgg tctgtggcat tagagataaa tggtttcaca aatatatttg
     4261 aacaaactag ccctgatttt gtattattac taggggatag aggagaaatg ttggcagctg
     4321 cgatagcttg tttgtatctt ggaatcaaaa cagcacatat tcacggaggc gaagtgtctg
     4381 gtactgtaga tgaatcaata agacatgcca taacgaaaat agcatctgtt cattttgctg
     4441 ctacggaaaa aagcaaagag cgtttaataa aaatggggga agattcttgg agagtttttc
     4501 ccgtcggagc tcctagaata gatactattt taaataatag attacctagt tttagagata
     4561 taaaagaaaa atatcatcta aaatttgaaa agaaaaaata cgttttgcaa gtatttcatc
     4621 cagttgtaac cgaactagaa aatatagaaa aacaaatttt agctttgatc aattcaatgg
     4681 aacaacaatc tcaaccaatt atttgcattt tacctaatag tgatgctggt agcgaaatta
     4741 tcagaaaaat gtaccagaaa tatttaaaaa cggatattat ttatattacg aatttagagc
     4801 cggaggaata cctgactata ttaaaagagt gcaaatttat gatcggaaat tcttcttctg
     4861 ggataattga agctgcatca ttcaaaatac cagtaataaa tttaggaacc agacaaaatg
     4921 gacgagaaca atctaaaaat attataaatg caaatctaaa tgaaaatgaa attgaaactg
     4981 ctttgaataa aatacaagat cctcagttta taaaaagctt gaaaaatgtt aagaacatct
     5041 acggtgacgg caacagttct agaagaataa caaaaacatt gaatcaaata ttgaatgatg
     5101 gggaagatat taagtggatt caaaaacaaa tagcttatta aaatatacta gtgatccata
     5161 cattattatt ggggctggcg gacacgcaaa agtcattatt gaaaccttaa gattagaaaa
     5221 taagttaata tatggatttt ttgatgataa gcaaaataaa atgcaagatc tgaaatatct
     5281 tgggaaaata aacgaattga atagctgggc ggatagcaaa aaaaaaatct ataaatttat
     5341 tgtagctatt ggtgactgtg tagtaagaaa aaagattata aaaaaattga atatgccaag
     5401 tgagcaatat ggaatagctg ttcatccaag tgctatagtg gcaaaagaaa tttcaattgg
     5461 ttatggaact gttatttttg cgaatgctgt aattaaccca gatgctgtaa ttggagagca
     5521 tgctataata aacacaggta gcattgttga gcatgattgt agaattaata actatgttca
     5581 tttatctcca ggtgtatgct tagcgggtgg agtacatgta ggtgtaggaa ctcaaatagg
     5641 aattggttct caatgtatcc agatgaagaa aattggatct tggtgtatga taggcgcagg
     5701 gagcactatt gttaaggata ttccctcaca ttccttagct tatggcaatc cagctaaaat
     5761 taagaaagaa ggaattaatt ttgaattcta gaattttatt atcaagtcct catatgggag
     5821 gaacagaaga aaaatatgtt gctaaggctt ttaaagataa ttggatagcg ccattaggtg
     5881 aaaatgtgga taaatttgaa gaaagtatta caaaatatac tggttctaag ggcggagctt
     5941 ctgcgttaag ttcaggtaca gctgccatac atcttgcctt aagactgctt aatgttggaa
     6001 aaaacgatat tgtctttgct ccttcattta cttttatagc tacagtaaat cctattttat
     6061 atcaaggggc tgtaccagtg ttcattgact cagaacctaa tacatggaat atgagccctg
     6121 ttgcactaga gagcgcatta gaagaagctg aaagaaacaa ccaattacct aaggcaatca
     6181 tcgtagtgaa tttatatggt caaatggctg attatgaacg aattttagct attgcaaacc
     6241 aatttaatgt tccagtgata gaagatgcag cggaatcgtt aggttctact tataagggaa
     6301 tttcgtcagg cttatttggg acaattggga tctattcatt taacggtaat aagatcatca
     6361 caacctcagg tggaggagct ctagtgtcta gtgataaaaa atatgttgag cattcaagat
     6421 ttttagcaac acaagcaaga gatcaagcac cgtattatca acatagcgaa ataggttata
     6481 attaccgtct aagcaatatt tctgccggta tcggacgtgg acaaatggaa gtattgaatg
     6541 atagagtagc taaacgaaga gaaattttca atcgatataa ggaagctttt tctggaattg
     6601 atagaattga aatgatgcca gaagtggatg gcatggtgcc aaatcgttgg ttgtctactt
     6661 taacgatcaa tgattataat tctattgatc aagtagttaa cgtaataaat aaactaaatg
     6721 aaaaaaacat tgaaacaaga gctttgtgga aaccactaca tttgcaacca gtatttcaag
     6781 gggtaaaaat gtattaccat gataataatc ttagtgtgtc agaaaagtta tttaatagcg
     6841 gcttatgctt accttctgga agtaatatga cagatagtga acaagaattt gttattgatg
     6901 agtttaaaaa aatattcaag taggtgtgat attttatgaa cataggaatt attggtttag
     6961 gttccatggg gaaaagaaga cttagactca ttcaagaaca ctttaatgat attttactat
     7021 gtggtgttga tactaatgag gcgagacgaa aggaagttga aaaggaattt ggaataccaa
     7081 cttataatag tctaacagag gcaaaaaatt tgtttgaaat aaattcagtt tttgtttgta
     7141 catcccctat aacccatgaa tttattataa aagaggcttt aaatttagat tgtaatatct
     7201 ttacggaaat caatttatta aatgaatatt atgatgaaat aatcgaagta gctaaaaaga
     7261 aagatagatt actttatcta tcttctacat ttttgaagag aaaagaaatt caatatatta
     7321 agtctaaagt gacgcataat aaaaaaattt cttatcaata ccatgtagga cagtatttac
     7381 ccgactggca tccttgggaa gattatcgca atttttttgt ttcaaacaaa aaaactaatg
     7441 ggtgtagaga aatattcgct attgaattac cttggattat agatacattt gggaaagtta
     7501 aatcgtttac tgtaatgacc cagaaattat ccaatcttga tattgattat tcggacagtt
     7561 tcactcttat tattgagcat gaaactggta tagttggaac tttaagtgta gatgttgttt
     7621 caagagtagc taaaagaaat ttaactataa ttggtgaaaa gattttaata gaatgggaag
     7681 gtaacccgga ttctctattt tcatggaatg aagaaacttc tagtatgaca gatattcaat
     7741 tgtacgatga ggttatgcat gataataatt attcacatac tattattgaa gatgcatatt
     7801 tagaggagat taaagaattt ttcacgcttt tggaaaagaa aatggaaccc caatatactt
     7861 ttgaaaaaga taagtatatt attaacttaa ttaacgacat tgaggtaaat taatgatgaa
     7921 agtaattttt tttgggttag ggtcaattgg aaagagacat ctaaaaaatc taataagcta
     7981 tggaaaaaag aattctatta attttgatat aacagcttat agtagcagtg gaaaaaaaga
     8041 gtttgaagaa ataacgtata ttcaaaatag agacgatttg gatacacatt atgatatagc
     8101 ttttattaca aatccgactt ttaagcatct ggaaacacta aatgtaattg ttgaaaaagt
     8161 tgattacata tttttagaaa aacctgcttt ttctgagagt attgatctta ctcaatataa
     8221 ttatgattac aaaaatattt atgttgctgc tccactgagg tataaaaata tcatggaagt
     8281 tgttcgtaat agtattcaaa gtaaaaaagt atattctgta agagctattt gttctactta
     8341 tcttcctgat tgga
//
LOCUS       DAZKKZ010000092         8229 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.094, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000092 DAZKKZ010000000
VERSION     DAZKKZ010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8229)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8229)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8229
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.094"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            329..1252
                     /gene="truB"
                     /locus_tag="ACG8LA_002602"
     CDS             329..1252
                     /gene="truB"
                     /locus_tag="ACG8LA_002602"
                     /EC_number="5.4.99.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HFQ0204867.1"
                     /translation="MDGLLTLWKERGMTSHDCVFKLRKILHTKKIGHGGTLDPDVDGV
                     LPICIGKATKVIEYLTDSGKIYVGEITLGFSTTTEDRSGERVETKPVDMSLSEEKIDE
                     VMASFIGEITQIPPMYSAVKVNGKRLYEYARNNETVERPVRKAQIYRFIRTSELTRDE
                     VTGTISWRFEVECGKGTYVRTLAVDTGKKLGYPAHMSDLTRTASAGMSQKDALTLEEV
                     AQAVKNGTIDDCLLPIEKGVKRFKRVDITDEVWQKVKNGMRLNYTVFALPEMPSEEIA
                     LFYKGKVVSIYQPNPKEKNKLKPSKVLRNEE"
     gene            1256..2197
                     /gene="ribF"
                     /locus_tag="ACG8LA_002603"
     CDS             1256..2197
                     /gene="ribF"
                     /locus_tag="ACG8LA_002603"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003919 - FMN adenylyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006747 - FAD biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009398 - FMN biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin biosynthesis protein RibF"
                     /protein_id="HFQ0204868.1"
                     /translation="MNIIKIRHPYQSEQIPEDDVVLVLGFFDGVHIGHQKVIKTGMEI
                     AQKEGLKLALMTFNQHPSIVFKKIDPSSVKYLTSLKQKEEKMAALGIDYLYEVDFTSS
                     FAHLAPQEFVDQYIVGLHAKYAVSGFDYTYGPKDIADVAHFPEYAKGRFKIVTVSKEE
                     EQGEKISSTRIRGLLDSGQVKEAAKLLGCTYEVEGVVVHGDARGRLLGFPTANVKVKS
                     TVHLPKEGVYVSEIKIGEIWYPAMGSIGHNDTFGEGRELTVELYILDFNQDIYGEHVA
                     VRWNQFLRDQVKFSSVEELIEQLKEDEQATAEYFSQQ"
     gene            2592..3377
                     /locus_tag="ACG8LA_002604"
     CDS             2592..3377
                     /locus_tag="ACG8LA_002604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HFQ0204869.1"
                     /translation="MYKELENKVAVVTGGSKGIGTAIAQRFGKEKMNVVVNYNSDKEG
                     AEKAVKAIEEAGGKAVSVQADVSSEEGIQRLLDTALENFGTLDVWINNAGMENQHPTH
                     ELSLEDWERVLKVNLTGVFIGTKAALNYFTENDKKGNIINMSSVHEQIPWPTFAHYAA
                     SKGGVKLFTETVAMEYAPKGIRINSIGPGAIRTPINAAKFDDPEQKELLESMIPLGRV
                     GEPKEIAATAAWLASDESSYVTGITLFADGGMTLYPSFQGGKG"
     gene            3390..4241
                     /locus_tag="ACG8LA_002605"
     CDS             3390..4241
                     /locus_tag="ACG8LA_002605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015144 - carbohydrate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0034219 - carbohydrate transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GRP family sugar transporter"
                     /protein_id="HFQ0204870.1"
                     /translation="MGLLIALIPAVGWGIQPLILKKIGGRPTNEILGTGIGAVLVGLL
                     VQLFASPAGISVTTFLISLLSGAFWVIGQTGQYTSFNLIGVSKTMPISTALQLVGTSL
                     IGVFAFGEWSGSMGKIIGAAAIILLVFGSALTAISDDPGKKGGITKGISLLASTSIGY
                     WVYSALPKLVDASGLSIFFPQMIGVFLGAVIYVIFRKPTAFSEDKSWKATIVGAIFSV
                     SALAYIFSANENGVATAYIITQLNVVISTLGGMYILHENKTPKEKKLTIIGLLLIVVG
                     SMVTVFI"
     gene            complement(4365..4817)
                     /locus_tag="ACG8LA_002606"
     CDS             complement(4365..4817)
                     /locus_tag="ACG8LA_002606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0204871.1"
                     /translation="MKDFYSVNELAEQLGVTTRSIRNYLHEGKLKGTKVGGQWKFSER
                     NLFEFLYGDQAEEAAKEMQRFMLNAPITMRFNLQYRDFTAINQIREQLVQYHNDVYAN
                     KKDRLLQYDLYKDNHAEILIGGNFNHVVNFSQWINEKLLMQTDISLVS"
     gene            complement(5282..5650)
                     /locus_tag="ACG8LA_002607"
     CDS             complement(5282..5650)
                     /locus_tag="ACG8LA_002607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1801 domain-containing protein"
                     /protein_id="HFQ0204872.1"
                     /translation="MEKFQPIINQIKEKEHQQKIKDLFAKITETYPQLDTTVKWNQPM
                     FTDHGTFIIAFSFAKNHFSIAPEKAAIRALEKNIQEAGYVYTDNVIKVPWKSVINWEL
                     IEQLISFNIEDKKGHDKFWR"
     gene            5800..6282
                     /locus_tag="ACG8LA_002608"
     CDS             5800..6282
                     /locus_tag="ACG8LA_002608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0002161 - aminoacyl-tRNA editing activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YbaK/EbsC family protein"
                     /protein_id="HFQ0204873.1"
                     /translation="MIDLAKKFLHENIYFELYHHRAIYTNEDALVIKKEQGFTGTETK
                     SLFLKDKKDNNYVYLTFTTKQTDFKALGKIVGKRLSIVSSERMEEQTGQKQGAVSPFG
                     YEKQIPIIIDEELLSNEKLVFAPGRPDQTMVIQTVDLNKIIQLLEMPIFLMPANEKNN
                     "
     gene            6319..7329
                     /locus_tag="ACG8LA_002609"
     CDS             6319..7329
                     /locus_tag="ACG8LA_002609"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S66 peptidase family protein"
                     /protein_id="HFQ0204874.1"
                     /translation="MISYPLLERNATIGVTAPSSGVSEEHHSLLESALKRMEEKSFQV
                     VTGKTLWTQDKEKSGPARKRADEFNQMMQDENIQMIFPPWGGELLIEILDFVDFDALQ
                     PKWIVGYSDISTLLLAVTLKTGIATAHGTNLIDLRGEYLDETTAMWESVLKTREGESI
                     LQQPSEKYQKEWPHEHSSSSVFHLTEPTNWQSVSGDAVRMKGRLLGGCIDTISHLIGT
                     PYGDVQSFKRKYNDGKPILWFLENCELSSVDLRRSLVQMKLAGWFDGSSGIMFGRSAA
                     EDLLDYKMKDVYEDLSKELKLPILYDIDCGHVPPQLTLINGAYAEVAVEDRKATVLQT
                     FI"
     gene            complement(7444..8157)
                     /locus_tag="ACG8LA_002610"
     CDS             complement(7444..8157)
                     /locus_tag="ACG8LA_002610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204875.1"
                     /translation="MKKLGFILLLVSLFLVGCTSPSKENSDPSATTDKSSIKQTSSAE
                     KSSTQKSASTETNTSSTSSKVSEPNTSSTSSSTVETNISSSTIDTTSSQSSQSIDPLA
                     GYSDLQIEYARVWLAIRGNTFRDTSGDFELHVIHYPAGTPIAPYDAGSAVYPKDVVML
                     TGKYSYQGVLVYSSNHDGTITSYPVPSHWQMPADQTSYPAFIRETTQEIIDNASVVAI
                     PTGNPNDVKQLINVIVMDN"
BASE COUNT         2785 a         1337 c         1667 g         2440 t
ORIGIN      
        1 attaagaaac tgaaaaaata aataaaaaaa aacggaaaaa agactggaag aatggacagt
       61 cttttttttc gtttttggga agtgaaaacc aaactattta cctgtaagcc acccataaat
      121 ccaatcaaat ggtgcaaaga aaaaatcttc cattctattc cctcctttaa aaaaaacata
      181 acatgatttc tatttacgtg agcatgaatt ttgttacgtt tttattgccg aaaaataaaa
      241 accgttcatt atgatgtcaa attcgtcagt aattgatgca atgtgttata ataattcagt
      301 taaatcaaaa atgaaatgga gaaaagacat ggacgggtta ttaactttat ggaaagaacg
      361 cggaatgaca agtcatgatt gcgtattcaa attaagaaaa atcttacata cgaaaaaaat
      421 cggacatggg ggtacgcttg acccagacgt agacggtgtg ttgcccattt gtattggaaa
      481 agccacaaaa gttatcgaat atttgacaga ttctgggaaa atctatgtag gcgagataac
      541 tctaggtttc agtacaacga cggaagatcg atccggagaa cgggtagaaa caaaaccagt
      601 agatatgtct ttatctgaag aaaaaataga tgaagtgatg gcttcattta ttggtgagat
      661 cacccagata ccaccaatgt actcagcggt aaaagtcaac ggtaagcggt tatatgaata
      721 tgcccgcaat aatgaaacag tggagcgtcc tgttagaaag gctcagattt accgttttat
      781 ccggacaagt gaattgacaa gagacgaagt gacaggaacc atttcttggc gcttcgaagt
      841 agaatgcggg aaaggaacct atgtccgcac attagctgta gatacaggca agaaacttgg
      901 ttaccctgcg cacatgtctg atctgacccg aacagcaagt gccggtatgt cccagaaaga
      961 tgctctgaca ttagaagaag tagctcaagc tgtgaaaaat gggacaatcg atgattgttt
     1021 gctgccaata gaaaaaggag tgaaacgatt caaacgagta gatattactg atgaagtatg
     1081 gcagaaagta aaaaacggta tgagacttaa ttatactgta tttgcgctcc cagaaatgcc
     1141 gtcagaagaa attgctttgt tttataaagg caaagttgtc agtatctatc agccaaaccc
     1201 gaaagaaaaa aacaaattaa aacctagtaa agtattgaga aatgaggaat aacgaatgaa
     1261 tatcatcaag atcagacatc cttaccaatc agaacaaatt ccagaagacg atgtcgtttt
     1321 agtactagga ttttttgacg gcgtgcatat tggacaccag aaagtcataa agacaggtat
     1381 ggaaattgca caaaaagaag gattgaaatt agcattgatg actttcaatc agcatccatc
     1441 gattgtcttt aaaaagatcg atcctagcag cgtgaaatat ttgactagcc ttaagcaaaa
     1501 agaagaaaaa atggccgctt tgggtataga ttatttatat gaagttgatt ttacttcttc
     1561 ttttgctcat ttagcaccgc aggaatttgt tgatcaatac atcgtagggt tacatgcaaa
     1621 atatgctgtt tccggttttg attatacgta tggaccaaaa gacattgcag atgtcgctca
     1681 ttttcctgaa tatgccaaag gaagattcaa aatcgtcaca gtttctaaag aagaagaaca
     1741 aggtgaaaaa atcagctcta cccgtattcg aggattacta gacagcggac aagtaaaaga
     1801 agcagcaaaa ctattaggtt gcacatatga ggtagaaggg gtagttgtcc atggcgatgc
     1861 acgaggcaga ctactaggat tccctacagc aaatgtcaaa gtaaagagca cagttcattt
     1921 gcctaaagaa ggtgtttatg tatcggaaat aaaaattggg gaaatttggt atccagccat
     1981 gggttcaatt ggacataatg atacattcgg tgaaggacgg gagctgactg tagaattgta
     2041 tattttggac tttaatcaag atatctatgg tgaacatgtc gcagtacgct ggaatcaatt
     2101 tttaagagat caagtgaaat tttctagtgt agaggaattg attgaacaac tcaaagagga
     2161 tgaacaagca acagctgaat atttttctca gcaataaaac attatgcata aaatctcttg
     2221 tttatgtata actagcaatt tcaataaaat gggtgataaa taagcccagg aaaggggctg
     2281 tgacaaaagt cttgtcacag cctttttttc caaataaatg gtttttcaga agtagcttct
     2341 tcggaaataa gccgaaattt cacaaaaatt tgagaagtaa tttttgtaaa ttacttctta
     2401 tttcttgaag ctggccactt ctgtcacaac ctctttcttt atagaaataa aaggacacta
     2461 gcaattcatg aaaacgattg ctaaagcgta tcatttgctt tagactatat atcttggtgt
     2521 acactcactt taagacggaa ataaaagtta tccgtaataa caggtttagg tatgaaaaag
     2581 gagtgggtac tatgtataag gaattagaaa acaaagtcgc agtagtaact ggtggctcaa
     2641 aggggattgg aacagcgatt gctcaacgat tcgggaaaga aaaaatgaat gtagttgtca
     2701 actataactc ggataaagaa ggagcagaaa aagcagtcaa agcaatcgaa gaggcaggcg
     2761 gaaaagcagt ctctgtacaa gcagatgtca gttctgaaga aggaatacag cgtttacttg
     2821 atacggcttt agaaaatttt gggacactgg acgtttggat taataatgct gggatggaaa
     2881 atcagcatcc aacccatgaa cttagccttg aagattggga aagagtatta aaagtcaatt
     2941 tgactggcgt ttttatcgga acgaaagcgg ctttaaatta ctttacagag aatgataaaa
     3001 aaggaaatat catcaatatg tcttctgttc atgaacaaat cccatggcca acgtttgctc
     3061 attacgctgc ttcaaaaggc ggagtaaaac tattcaccga aacggtagca atggagtacg
     3121 caccaaaggg aatcagaatc aatagtatag gacctggtgc tatccgtaca cctattaatg
     3181 cggcaaaatt tgatgatcct gaacaaaaag aactcttgga aagtatgatc ccactaggac
     3241 gcgtaggtga accaaaagaa atagcggcga cagctgcatg gttggcttca gacgaatcca
     3301 gttatgttac aggtattaca ctatttgcag atggtgggat gactttatat ccttctttcc
     3361 aaggtggaaa aggataaggg tgaataaaaa tgggtttatt gattgcattg atcccggcag
     3421 ttgggtgggg gatccagcca ctgattttga aaaagattgg tggcagacca acaaatgaga
     3481 tattaggaac tggtattgga gccgtgctcg ttggcttact tgttcaatta ttcgcttctc
     3541 cagctggtat ttcagtgact acatttttga ttagtttact ttctggtgca ttctgggtca
     3601 tcggacaaac aggacagtat acatctttca acttgattgg tgtttctaaa acgatgccaa
     3661 tttcgactgc attacagtta gtcggaacct cattgattgg tgtcttcgct tttggagaat
     3721 ggtctggaag tatgggaaaa atcattggtg cagcagcaat cattcttctt gtatttggtt
     3781 ctgctttaac ggcaatcagt gatgatcctg gaaaaaaagg cggtatcaca aaaggaatca
     3841 gtctattagc atcaacaagt attggttatt gggtttacag tgcattgccc aaactagttg
     3901 atgcaagcgg actttccatt ttctttccgc aaatgatcgg tgtcttttta ggggcagtga
     3961 tttatgtgat tttccgaaaa ccaaccgcat tttctgaaga caagagttgg aaagcaacaa
     4021 tagttggagc catcttcagt gtgtcagcat tggcttatat tttttcagca aatgaaaatg
     4081 gggttgctac tgcatatatc attacacagc taaacgtagt tatctctaca ttaggcggta
     4141 tgtacatcct gcatgaaaat aagacaccaa aagaaaaaaa attaacgatt atcggattat
     4201 tgctgatcgt agtaggaagc atggtcacgg tctttatttg aggataaaga tggtaaaatc
     4261 tcatttatta aaaaaatatt tgtttgaacc aaacagtaag tacttataaa aaaatagcgc
     4321 tagaatttcc aacatctctg gaatttctag cgctttttaa ttgtttaaga tacaagtgaa
     4381 atatctgtct gcatcaataa tttttcattg atccattgac taaaatttac gacatgattg
     4441 aagttaccac cgattagtat ctccgcatga ttgtctttat aaagatcgta ttgtaaaaga
     4501 cggtcttttt tatttgcgta aacatcgtta tggtactgga ctaattgttc tcggatttga
     4561 ttgattgctg taaaatcacg atactgaagg ttgaaacgca tcgtgattgg tgcatttagc
     4621 atgaatcgct gcatttcttt tgctgcttcc tctgcttgat ctccgtatag gaactcaaaa
     4681 agattacgtt cagaaaattt ccattgcccg ccaacctttg ttccttttag ttttccttca
     4741 tgaagataat ttctgataga acgtgtagta acacctaatt gttcggctaa ttcatttact
     4801 gagtaaaaat ctttcaatgt tcaccctcct atgtgaatgg ttctactgac ttagttgata
     4861 tttgcttaat cacgaaatgt agaaagaacg attttaatta aggtcattgt aaaaatcaag
     4921 tcagaaaatt ctaacttttc tttctctaaa gaaattcgtt ctctcctaaa gtgatattat
     4981 atttaaatat acctgaaaat aatgggcagt attatgaaag atcactgata ttttctcgta
     5041 ttttttcctt attcaaaagt tttgcaggaa aattgctgaa aaaataattt tactaagtgg
     5101 aaaattcaaa gccattcaat cagtgatttt tttcagcaca agaaagactc cttataaaaa
     5161 tagcagatac tttgtcaatt aagtgtttaa ccagggatga taaaaaggat aggattgaac
     5221 aaaacctgta taagctgatg aatagtttcc tcgccagtaa aaggtttatt cgtataaagc
     5281 tttatcgcca aaatttatca tgaccttttt tatcttcaat attaaatgaa atcaattgtt
     5341 caatcaattc ccagttgatt acacttttcc aaggaacttt gatgacgtta tccgtatata
     5401 cgtagcctgc ttcttggata tttttttcaa gggcacgaat cgctgctttt tccggtgcga
     5461 tagaaaaatg atttttagca aaactaaatg caataataaa ggtaccatgg tcagtaaaca
     5521 taggttggtt ccattttaca gttgtgtcta gctggggata cgtttctgtt atcttagcaa
     5581 aaaggtcttt gatcttttgt tgatgttctt tttctttgat ctgattgatg atcggctgaa
     5641 atttttccat tctaaaacgc ctccattaag tggtttgatt tattttacca gaaaaacaat
     5701 agttatgtat aaaaaacgaa caaaacacaa gtaatgttgt aaccgctata tttatatgat
     5761 aagatgtctc aaataataaa atagaaaaga gacataaaaa tgattgactt ggcaaagaaa
     5821 ttcttacacg aaaatatata ttttgagttg tatcatcatc gagccattta tacaaatgaa
     5881 gatgctttgg taataaagaa agaacaagga tttacaggta cagagaccaa aagcttattc
     5941 ttaaaagata aaaaagataa taactacgta tatctgactt ttactacgaa acaaacggat
     6001 ttcaaagcat tagggaagat cgtcggtaaa aggctttcta ttgtttcatc agaacgcatg
     6061 gaagaacaaa cgggacaaaa gcagggcgct gtttctccgt ttggttatga aaaacagatt
     6121 ccgattatta ttgatgaaga gctcttatca aatgaaaaac ttgtttttgc accaggtaga
     6181 ccagatcaaa cgatggtcat ccaaacggtt gacttaaaca aaatcatcca gctacttgag
     6241 atgccgatat ttttgatgcc ggcaaacgaa aaaaacaatt aaccaagtaa aatagtgcat
     6301 acttggaggt gaagcaacat gataagttat ccattattag aaagaaatgc aacgattggg
     6361 gttactgcac catcctcagg cgtatcagag gaacaccatt cgttactcga atcagcttta
     6421 aagagaatgg aagaaaaatc tttccaagta gttactggaa agacgctttg gacgcaagat
     6481 aaggaaaaat caggtccagc aagaaaacga gcagatgaat tcaatcaaat gatgcaagat
     6541 gaaaatatcc aaatgatctt tccgccttgg ggaggagaat tattgattga gattctcgat
     6601 tttgtcgatt ttgatgctct acaaccaaaa tggatagtag gttattcaga tattagtacg
     6661 ttgctacttg ctgtcacatt aaaaacaggg atagccactg cacatggaac caaccttatt
     6721 gatttaagag gagagtactt ggatgaaacg acagcaatgt gggaaagtgt actgaaaaca
     6781 agagaaggag aatcgattct acagcaacct tctgaaaagt atcaaaaaga gtggccccat
     6841 gagcattcat catcttctgt tttccatctc actgaaccaa caaattggca atcagtcagc
     6901 ggagatgcag taaggatgaa gggacgatta ttaggtggct gtattgatac gatcagtcat
     6961 ttaatcggta ccccttatgg agatgtccaa tcttttaaaa gaaagtataa tgatggaaag
     7021 ccgatcttgt ggtttctaga aaattgtgag ctatcgtcag ttgatttaag aagatcactt
     7081 gttcagatga aactggcagg atggtttgat ggcagctcgg ggatcatgtt cggtagaagt
     7141 gcagcagagg atttgttaga ttataaaatg aaggatgtat atgaagatct gtcaaaggaa
     7201 ttaaaactac cgatcttgta tgatattgat tgtggtcatg taccgccaca actgacattg
     7261 atcaatggtg cctatgcaga agtagcggta gaagatagaa aagcgactgt tttgcaaacg
     7321 tttatttaaa aaattttttc ctgccttgga gtttatcaaa gaccaacaaa tctaaataga
     7381 aaagaaaatg aaagaagctg acagtatttt gccagcttct ttttgtatga tctattagaa
     7441 attttaatta tccataacta tcacattgat cagctgtttc acatcatttg gattacctgt
     7501 aggaatagct actacagatg cattatcaat aatttcttga gttgtttctc taatgaacgc
     7561 tggataagat gtttgatctg caggcatttg ccaatgtgaa ggaactggat aactagtgat
     7621 tgtcccgtca tggttacttg aatacactaa aactccctgg taactgtatt tcccagtgag
     7681 cataaccaca tctttcggat agactgcact ccctgcatca taaggggcga taggtgttcc
     7741 tgcaggataa tgaataacat gtagttcgaa atcacccgat gtatctctaa aagtattacc
     7801 tctaattgct agccaaacac gtgcgtactc aatttgtaga tcagaatatc ctgctaacgg
     7861 atctattgac tgagaagact gtgaggaagt tgtgtctatt gttgaagaag aaatatttgt
     7921 ctcaactgta ctactagatg tagaagaagt attgggctct gagactttac tgcttgttga
     7981 agatgtattc gtttcagtag aagctgattt ctgagtactt gatttttcag ctgaactggt
     8041 ttgtttgatt gaacttttgt ctgtggtcgc agatggatca ctattttctt tactaggaga
     8101 cgtacatcct acaaggaata aagagaccaa caataaaata aaacctaact ttttcatata
     8161 aaatacctca ttattttttt aataccagta tagcataatc ctgaattttt gaatccgtaa
     8221 aaccttgtc
//
LOCUS       DAZKKZ010000093         7867 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.096, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000093 DAZKKZ010000000
VERSION     DAZKKZ010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7867)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7867)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7867
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.096"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(69..1490)
                     /gene="tyrP"
                     /locus_tag="ACG8LA_002611"
     CDS             complement(69..1490)
                     /gene="tyrP"
                     /locus_tag="ACG8LA_002611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0070908 - tyrosine:tyramine antiporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-tyramine antiporter"
                     /protein_id="HFQ0204876.1"
                     /translation="MSKSEVSKMGLGTFIGLTMALCATVRSIPTLAAVGWTLIFYSIF
                     AVLFFAGPISMVSGELSTMLPQEGGPQLWVKTALGSKWGFVVAWLLWVQMFPGMVMVA
                     STLGPLLGNTFGNVELGNNHWFVLGCILVIYWIITILNLKFDMAKVGGNIGVWLGVYI
                     PVVIMFVLGVLAAFKVGLVSNGYLGDFSWSKAFPDLEHIDSLKYLAGITFIFVGIEMS
                     SVYMPRLKDATKNYTKGVFIALIGLVLLNVINAMLVANVVPDGKMELANITQPILIDC
                     QILGLPEVIGNIFSFMVFIGVLLQLSAWVTGPSKTIIQVAREGFLPPKFGFHKENKYG
                     VSRNVVLTQSIVISLFALLYGVMDDVSAVFLTLTNATTVIYCIVYILIAVSLLKMRKK
                     HPEFERPYRIGKNGNGLAWVVSCMLIFSIIVVVFATLGTATLSDALLVAAITVVMFVI
                     PLIINHFKKDSWGIEVEKSLEEK"
     gene            complement(1733..3610)
                     /gene="tdc"
                     /locus_tag="ACG8LA_002612"
     CDS             complement(1733..3610)
                     /gene="tdc"
                     /locus_tag="ACG8LA_002612"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004837 - tyrosine decarboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006572 - tyrosine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HFQ0204877.1"
                     /translation="MSESLSKDLNLNALFIGDKAENGQIYKALLNELVDEHLGWRQNY
                     MPQDMPIITPEEKSSASFEHTVNKTKDVLSEISARMRTHSVPWHNAGRYWGHMNSETL
                     MPSLLAYNFAMLWNGNNVAYESSPATSQMEEEVGMEFAKLMSYKDGWGHIVADGSLAN
                     LEGLWYARNIKSLPLAMKEVTPELVAGKSDWELMNLSTEEIMNLLDSVPEKIDEIKAH
                     SARSGKHLEKLGKWLVPQTKHYSWLKAADIIGIGLDQVIPVPVDHNYRMDINELEKIV
                     RGLAAEKTPILGVVGVVGSTEEGAIDGIDKIVALRRVLEKDGIYFYLHVDAAYGGYGR
                     AIFLDEDNNFIPFEDLKDVHYKYNVFTENKDYILEEVHSAYKAIEEAESVTIDPHKMG
                     YVPYSAGGIVIKDIRMRDVISYFATYVFEKGADIPALLGAYILEGSKAGATAASVWAA
                     HHVLPLNVTGYGKLMGASIEGAHRFYNFLNDLSFKVGDKEIEVHPLTYPDFNMVDYVF
                     KEKGNDDLVAMNKLNHDVYDYSSYVKGSIYGNEFLTSHTDFAIPDYGNSPLQFVNQLG
                     FSDEEWNRAGKVTVLRASVMTPYMNKEEHFEEYAEKIKAALQEKLEKIYADQLLASEA
                     K"
     gene            complement(3901..5157)
                     /gene="tyrS"
                     /locus_tag="ACG8LA_002613"
     CDS             complement(3901..5157)
                     /gene="tyrS"
                     /locus_tag="ACG8LA_002613"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004831 - tyrosine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006437 - tyrosyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HFQ0204878.1"
                     /translation="MNIIDELTWRDAINQQTNEERLRELVEEKSISLYCGVDPTGDSM
                     HIGHLIPFMMMKRFQLAGHHPYILIGGGTGTIGDPSGRKTERVLQTMEQVQHNVDALS
                     NQMRKLFGKDANITFVNNYDWLSKISLLEFLRDYGKNFNINTMLAKDIVASRLEVGIS
                     FTEFTYQILQSIDFLHLHKTYDVQLQIGGADQWGNITAGLDLIRKLEGPEAEAFGLTI
                     PLMLKADGTKFGKTAGGAVWLDPKKTSPFEFYQFWLNQDDRDVVKYLKFFTFLSQEEI
                     EDLAKKVETEPEKREAQRRLAEEVTRFVHSEEDLKEAQKITQALFSGNIKELNAEEIA
                     QGFGKMPNVEISSTPENIVELLVSTKIEPSKRQAREDVSNGAISINGDRVTDLNFVIN
                     PSDEFDGKFVVIRKGKKNYFLAKVID"
     misc_binding    complement(5269..5474)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            5737..7038
                     /locus_tag="ACG8LA_002614"
     CDS             5737..7038
                     /locus_tag="ACG8LA_002614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HFQ0204879.1"
                     /translation="MEKKQKIILGATSALTIVILILSLFFVIRSSTKKEPIIPEKKIT
                     EKAKEPTDDKQQLVTQAKNLAQSYDYDQAIALLEKDSKNGSTETQQLLQTLKKEKEQL
                     IDWSDPTQISHVFFHSLIVDPQKAFHSQQAQGYKDYMVTVEEFNRSIEQLYQNDFVLV
                     NLNDLIQKDEQGNLSFNGLALPEGKKPLVLSQDDVSYYEYMDNSGFPSRLVVSNNNEI
                     KNVYKEKDKEEIGDFDMVPLIDAFVKKHPDFSYRGAKGTLALTGYNGVLGYRTSKSQY
                     GDNEKTKKEIKEAKKVAEQLKKDGWSFASHTWGHLNMTQASLEDVKKDNELWQQEVAP
                     ILGKTNILIYPFGADISDWQPYSAENQKFAYLKSQGFDIFCNVDASTPAWGQLGTDFY
                     RNARINIDGIRFQSDLDGKNPILDPFINVHDVYDKEARESA"
     gene            complement(7107..7706)
                     /locus_tag="ACG8LA_002615"
     CDS             complement(7107..7706)
                     /locus_tag="ACG8LA_002615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFQ0204880.1"
                     /translation="MNGFEKRAQEKKKEILQAAFDLMNTDIGTAGVTMDKVAENAQVS
                     KATIFKYFGSKEGLIYEVFFAFMNDLGQEAKALIAENLPFEETLIAMSENKIRYLNRV
                     NKQFYIDLMTYYTKKEKKEFSDAMDAYTQESFSIMLDLFHRGRKEGKVDLKYSDEFLI
                     LYFQAMVEGISKPEIYAKLLPYTAEWTEVLIKGIAPKKK"
BASE COUNT         2344 a         1600 c         1374 g         2549 t
ORIGIN      
        1 aaaactattc acttggcagg acctcctact aaatcagcga caaaacgtcg gctgaaagac
       61 ttattttttt atttttcttc taaacttttt tctacctcaa tcccccaaga atctttcttg
      121 aagtgattga tgatcaatgg aataacgaac atgaccactg tgatagctgc tactaataat
      181 gcatcactca atgtcgctgt acctaatgta gcaaatacga caacgatgat agagaagatc
      241 agcatgcagc tgactaccca agctaatccg tttccgtttt taccaattcg gtaaggacgt
      301 tcgaattctg gatgtttctt acgcatttta agcaatgaaa cagcaatcaa aatgtacacg
      361 atacaataaa taacagttgt agcatttgta agtgtcaaga atacagcact tacgtcatcc
      421 attacaccat aaagcaaagc aaataatgaa ataacgattg attgtgttag aacgacattt
      481 ctagatacgc cgtatttgtt ttctttatgg aatccgaatt ttggtggaag gaatccttca
      541 cgagctactt ggatgattgt ttttgatggt ccagtaaccc aagctgataa ttgtaaaagc
      601 acaccaataa ataccatgaa gctgaagata tttccgatca cttctggtaa gcctaggatt
      661 tgacagtcaa tcaagatagg ctgcgtgata tttgctaatt ccatttttcc atctggtacg
      721 acatttgcta caagcatcgc attgatgaca ttcaataaaa ctaatccgat caaagcgata
      781 aatacgcctt ttgtataatt ttttgttgcg tctttcaaac gaggcatgta aacagaactc
      841 atttcgatcc caacaaaaat aaatgtgata ccagctaagt atttcaatga atcaatatgt
      901 tccaagtcag ggaaagcttt tgaccatgaa aagtcaccta gatagccgtt tgagactagt
      961 ccgactttga aggctgccaa aacacctaaa acgaacatga tgactactgg gatatatacc
     1021 cctagccata caccgatgtt cccgccgact tttgccatat cgaatttcaa gttcaagatc
     1081 gtgatgatcc agtagataac taaaatacaa cctaaaacga accagtgatt attgccaagt
     1141 tctacattac caaatgtgtt tcctaacaat ggtcctaaag tagaagcgac cattaccata
     1201 cctgggaaca tttgcaccca taatagccat gcaacgacaa atccccattt gctgcccagt
     1261 gctgttttta cccataactg aggaccgcct tcttgaggaa gcatcgtgga aagctcaccg
     1321 gaaaccattg atatcggacc ggcaaaaaac aaaactgcaa aaattgaata aaaaatcaat
     1381 gtccaaccga ctgcggctaa cgtaggaata ctccgaaccg ttgcacacag tgccattgtc
     1441 agaccgataa aggtcccaag acccatttta cttacttcag atttactcac cgttgacact
     1501 ctccttgatt ttttggataa aataacggtg tctttgaagt agtttcagca ataaacgaaa
     1561 caattcagcg aatatttgag gggattcttt gagtttattg cttgaagggt ttcttcaaag
     1621 acaacctcaa aacaaaggga tcgaagagct taggtctccc cttgctcttc agatccaaac
     1681 atgcgtcaga aacagttagt attcaagctg ttttctaaca tgattacctt gcttattttg
     1741 cttcgcttgc caataattgg tctgcgtaga ttttttccaa tttttcttga agagctgctt
     1801 tgattttttc agcatattct tcaaagtgtt cttctttgtt catgtatggt gtcattacgc
     1861 tggcacgcaa tacagttact tttccggcac ggttccattc ttcatctgag aatcctagtt
     1921 ggttcacaaa ttgtaatggg ctgttgccat agtctgggat agcaaagtca gtatgtgaag
     1981 ttaagaactc attaccgtaa atgcttcctt tcacgtatga agaataatca tatacgtcat
     2041 ggttcaattt attcattgca actaagtcat cgttgccttt ttctttgaat acatagtcta
     2101 ccatattgaa atctggataa gttaatggat gaacttcgat ttctttgtct cctactttaa
     2161 atgacaagtc attcaagaag ttgtagaaac gatgtgcacc ttcgattgat gcacccatta
     2221 atttaccata tcctgtgaca ttcaaaggta agacatggtg tgctgcccaa acgctggctg
     2281 ctgttgcccc tgcttttgaa ccttccaaga tataagcccc aagtaatgct gggatatctg
     2341 cgcctttttc aaatacatat gtcgcaaagt aagagataac gtctctcatg cggatatctt
     2401 tgatgacgat accaccggca gaatatggaa catagcccat tttatgtggg tcaatcgtta
     2461 cagattctgc ttcttcgatt gctttatatg cactgtgtac ttcttctaag atataatctt
     2521 tgttttctgt aaagacattg tatttgtaat gaacatcttt taaatcttca aatggaatga
     2581 agttgttgtc ttcgtctaag aaaatcgcac ggccgtatcc gccataagca gcatctacgt
     2641 gtaagtagaa gtaaataccg tctttttcta atacgcgacg caatgcaacg attttatcga
     2701 taccgtcgat tgctccttct tctgttgatc ctacaacacc gactacacct aggattggtg
     2761 ttttttcagc tgctagacca cgaacgattt tttcaagttc gttgatgtcc atgcgatagt
     2821 tgtggtcaac tggcactgga atcacttggt ctaaaccgat accgatgatg tcggcagctt
     2881 ttagccatga atagtgttta gtttgtggaa ccaaccattt tcctaatttt tctaaatgtt
     2941 ttccgctacg tgctgagtga gctttgattt cgtcgatttt ttctgggacg ctgtctaaca
     3001 gattcatgat ttcttctgtt gacaagttca ttaattccca atcgcttttt ccagcaacta
     3061 gttcaggtgt cacttctttc attgcaagcg gcaatgattt gatgttgcgg gcataccaaa
     3121 gtccttctaa gtttgctaaa gaaccatcag caacgatgtg gccccagcca tctttatagc
     3181 tcattaattt tgcaaattcc attcctactt cttcttccat ttggcttgtt gcaggagaag
     3241 attcataggc aacgttatta ccattccata gcatagcaaa attgtacgct agtaaagatg
     3301 gcatcaatgt ttcagagttc atatgacccc agtaacgtcc ggcattatgc caaggaacgg
     3361 aatgggtacg catccgcgct gaaatttctg atagaacatc ctttgtttta ttcacagtgt
     3421 gttcaaaact agcactgctt ttttcttctg gcgtaataat aggcatgtct tgaggcatgt
     3481 agttttgacg ccagcctaaa tgttcatcca ccaattcatt caacaaagct ttatagattt
     3541 ggccgttctc agctttgtcc ccaatgaata gggcatttag gtttagatct ttcgacaatg
     3601 attcactcat agtgaaaccc tcctaaaaaa atatttaaat tttgtcgagc cctacattac
     3661 acctgttctt ctattctgta aactaagttt tggcctgatt tttaatcata ttttaatatg
     3721 tatcaattat ccgaattgtt cacacttttg aaataattaa aaaaaacgag ggaatttaca
     3781 aatgtaaact ccctcgcaaa gattgtatta acgacaacca gcgttctatt ttaggatggg
     3841 tttcaaaatt ggaatgttgt aatagtattt ccctttttca aggtaaaaac ttactaaatt
     3901 ctaatcaatt actttggcca aaaagtaatt tttcttacct tttcgaataa ccacaaactt
     3961 accatcgaat tcatcggatg gatttatgac aaaatttaaa tcggtaacgc ggtcaccgtt
     4021 aatacttata gctccgtttg aaacatcttc acgtgcttga cgtttagatg gttcaatttt
     4081 tgtggaaaca agcagttcca cgatattttc aggtgtgctt gaaatttcaa cgttcggcat
     4141 tttaccgaat ccttgcgcga tttcttccgc atttagttct ttaatatttc cagagaacaa
     4201 tgcttgcgtt attttttgcg cttctttcaa gtcttcttca ctatgcacaa atcttgtaac
     4261 ttcttctgcc aaacggcgtt gtgcttcacg tttctcaggt tctgtctcta cttttttcgc
     4321 taagtcttcg atttcttctt gagacaagaa agtaaagaat ttcaagtatt tcactacatc
     4381 gcgatcatct tgattcaacc agaattggta gaactcaaat ggtgaagttt tcttcggatc
     4441 aagccaaacg gcaccgcctg cagtttttcc gaatttcgtt ccgtcagcct tcagcatcaa
     4501 tgggatcgtt aaaccgaacg cttctgcttc tggtccttct aattttcgga ttaggtctaa
     4561 tccagctgtg atatttcccc attggtctgc tccaccgatt tgcaattgca catcgtatgt
     4621 tttatgcaga tgcaaaaagt cgatagattg caggatttgg taagtaaact ctgtaaatga
     4681 gattcctact tccaaacggc tggcaacgat atcttttgct aacatcgtgt tgatgttgaa
     4741 gtttttaccg tagtctctca aaaattcaag taaagagatt tttgacaacc agtcgtagtt
     4801 gttcacaaat gtgatatttg catctttacc aaacaatttt ctcatttgat tggaaagtgc
     4861 gtccacgtta tgttgcactt gttccatcgt ttgcaacaca cgttctgttt tgcggccgct
     4921 tgggtcgccg atcgttcctg ttccgccgcc aatcagaata tatggatgat ggcctgccaa
     4981 ttggaatctt ttcatcatca taaatggaat caaatgtccg atatgcatcg aatcaccagt
     5041 tggatcaacg ccgcaataaa gtgaaatgct cttttcttca acgagctcgc gaagtctttc
     5101 ttcgtttgtt tgctgattaa tggcgtcgcg ccaagttaat tcatcaataa tattcatttt
     5161 actgacctcc gtgtagtttt tttatgaaag caggaacctg ctagcatgtg taattaatta
     5221 tttcttcagg ataggatagg aaataaaaaa agtcccttgg catataagcc aagggacgaa
     5281 atctcgcggt accacccaat ttgtatgtct agatatccaa catacctctc gaacatttaa
     5341 cgctgtcgcg tggcaatcac tgccaaagac tcctgaaatg taattcgctt taaagcatgt
     5401 actggtttgc agcgaccacc agctttctga aacattggct ttaacaacta cttcgtttcg
     5461 atcttcgtct tgttattatt aatatgtgtc tatcatagag cgcaactttt tctttgtcaa
     5521 cagaaaaagg atattttttt taaattcctc attttttctt ttttgaatcc gctctaattc
     5581 cgaacatttt attttcaatt attgttaaaa gaaataactt tttctgtatt ttttctgcaa
     5641 tttatcgaga agtcacttta ctttgcctct tattctttct tcgttacaat aaggaatggg
     5701 acaagtaaaa aaatgaaaaa gcaagggacg aggtatatgg aaaaaaagca aaaaattatt
     5761 ttaggagcca cttctgcttt aactatcgtt attttaattc taagtttgtt ttttgtcatc
     5821 cgatcatcta caaaaaaaga accaatcatt cctgaaaaaa aaataacaga aaaagcaaaa
     5881 gaaccgacag atgataagca acaactagtt actcaagcaa aaaatctggc tcaaagctac
     5941 gattatgacc aagcgattgc gttattggaa aaagatagta agaacggatc tactgaaaca
     6001 caacagcttc ttcaaacact aaaaaaggag aaagaacaac tgatcgactg gtctgatcct
     6061 actcagatct ctcatgtctt tttccacagc ttgatcgtgg acccgcaaaa agccttccac
     6121 tctcaacagg cacaaggata caaagattat atggtgactg ttgaagaatt caaccgttcg
     6181 atcgaacaac tttatcaaaa tgattttgtt ttagttaatt tgaatgattt gatccaaaaa
     6241 gacgaacaag gaaatctttc ctttaacggg cttgcgctac ctgaaggaaa aaaaccattg
     6301 gttctttcac aagatgatgt cagctattat gaatatatgg ataattccgg ttttcctagc
     6361 cgattggtcg tatcaaataa caatgaaatc aaaaatgtct ataaagagaa agataaagaa
     6421 gaaatcggtg actttgacat ggttcctctg atcgatgcct ttgtcaagaa acatcctgat
     6481 ttttcttatc gaggcgcaaa aggtaccttg gccctgacag gttacaacgg agttttaggt
     6541 tatcgaacat caaaatctca atatggagac aatgaaaaaa caaaaaaaga gattaaagaa
     6601 gctaaaaaag tggcggaaca gttgaagaaa gacggctgga gctttgcttc ccatacatgg
     6661 ggtcacttga atatgactca agcttcacta gaagatgtaa aaaaagacaa tgaattgtgg
     6721 cagcaagaag ttgcacctat cctaggaaaa acaaatattc tgatttatcc atttggtgca
     6781 gacatcagcg actggcagcc ttattcagca gaaaatcaaa aatttgctta cttgaagagt
     6841 caaggtttcg atattttctg taatgtcgat gcttctacac cagcttgggg acaattaggt
     6901 acggatttct atcgaaatgc tcggatcaat atcgatggca ttcgttttca atctgattta
     6961 gacggaaaaa atcctattct tgatccattc atcaatgtcc atgatgtcta tgacaaagaa
     7021 gcacgcgaat ctgcttgatt ttacgtcatt tatgaaccaa aaaagccgaa ctgacatttt
     7081 atcgtcagtt tcggcttttt tatgctttat ttcttcttcg gtgcgattcc cttgatcagg
     7141 acttctgtcc attctgctgt atatggaagc agttttgcgt atatctccgg cttagaaatt
     7201 ccttctacca ttgcttgaaa atagaggatc aagaactcat ccgaatattt caaatccact
     7261 tttccttctt tccgccctcg atggaaaaga tcaagcatga tactgaaact ttcttgcgta
     7321 tacgcatcca tcgcgtcaga aaattctttt ttttcttttt ttgtatagta tgtcatcaaa
     7381 tcgatataaa attgtttgtt cactcgattg agataacgga ttttgttttc actcatggca
     7441 atcagtgttt cttcaaatgg aagattttcc gcaatcaacg ctttcgcttc ttgccctaaa
     7501 tcattcataa atgcaaaaaa tacttcataa atcagccctt ccttgctgcc aaaatattta
     7561 aaaatcgtcg ctttacttac ctgagcgttc tcagctacct tatccattgt cactccagcg
     7621 gttcctatgt ctgtgttcat caagtcaaaa gctgcttgta aaatctcttt ctttttctct
     7681 tgtgctctct tttcaaaacc gttcatttgt agagcctccc gtaattttaa acttttataa
     7741 tatatatagt tcaaatttat tctgaggttt attataacta tctattgaga aagtatcaag
     7801 ctagcaattc cttgtttatg aattcattga cagaaattta taaaaagaat attatgtact
     7861 aaaataa
//
LOCUS       DAZKKZ010000094         7627 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.097, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000094 DAZKKZ010000000
VERSION     DAZKKZ010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7627)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7627)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7627
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.097"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(16..714)
                     /locus_tag="ACG8LA_002616"
                     /pseudo
     CDS             complement(16..714)
                     /locus_tag="ACG8LA_002616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
     gene            793..969
                     /locus_tag="ACG8LA_002617"
                     /pseudo
     CDS             793..969
                     /locus_tag="ACG8LA_002617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348541.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase"
     gene            complement(1145..1714)
                     /locus_tag="ACG8LA_002618"
     CDS             complement(1145..1714)
                     /locus_tag="ACG8LA_002618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HFQ0204881.1"
                     /translation="MELKKLEVPTSSITEVKRSPMDVFAQARDAGTGVYIFNREKVAG
                     VMLTQEQYETLLQELDVLRQTVKVERKEPKEINEEPINKTASVVSNAEGMEELAQTLQ
                     HSLITGVTITAKNLDERMVALGFITKKTGFGGVVDMLSELMETGKINYQLRRKPQNRT
                     IIAEIIGEQNSQSQLMDKIIIKKIFLHEL"
     gene            complement(1788..2111)
                     /locus_tag="ACG8LA_002619"
     CDS             complement(1788..2111)
                     /locus_tag="ACG8LA_002619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204882.1"
                     /translation="MLLLKTLQERGYLDVHPPEVKIVFFFRYEHQEARRLAGVLNKTL
                     RHRKRISIHVCTRNKPPRYADLVIIDHFFPLDHNEDQKTYLYHPSFGIERLLTDINYW
                     LGKNR"
     gene            complement(2265..3077)
                     /locus_tag="ACG8LA_002620"
     CDS             complement(2265..3077)
                     /locus_tag="ACG8LA_002620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008274430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204883.1"
                     /translation="MRWQKLLSKNAQNLFSLINLMKDLIWRKADLAEELKIDVKTVDR
                     HLKRLAESDCPIQLILHKKTVQLVYDQGYSEPYLLFVFLIQSPPFCLLKNLLLNEPYE
                     QKYDRSTQERLRKWFGEYHLSFSYKKAQIFGSERKVRYLLFCFLKDFPHFFADDGEQS
                     FSEMFIQLLKQRKDPAEIEILGDSRTLFFELFPELLFREEQILPIKEKNYLAILRLSC
                     NQITEKRWKRIEETQDYRKLTIVTEKLDSLFWLNSEFESESKSKLTKVLYQE"
     gene            3404..4279
                     /locus_tag="ACG8LA_002621"
     CDS             3404..4279
                     /locus_tag="ACG8LA_002621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010758089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFQ0204884.1"
                     /translation="MGKRSTIQLMIVALLAGGHVLFEDIPGVGKTLLVKALAKAVQGT
                     FSRVQCTPDLLPSDILGFSVYNSQSKEFEFRPGPIFTTILLADEINRTTPRTQSALLE
                     AMAENHATIDNNTYPLDNHFFVLATQNPIEYEGTYPLPEAQLDRFLFRLQIGYPSFDD
                     ELLLLLDKFEKVLDNLNEVLNSYEIEEIKTNVANVFVSPEVASYALQLVSATRSHAAI
                     QLGISPRGSLSFIQAAKAYALIHGRNYVTPKDLQDLVPYVFSHRLIFYDRSLKEDEKK
                     QIIHTLVAQIPIPVR"
     gene            4293..4616
                     /locus_tag="ACG8LA_002622"
     CDS             4293..4616
                     /locus_tag="ACG8LA_002622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204885.1"
                     /translation="MEKIKDYFINFVLFLVYFIIVLFALVFNNSLGWFLLAFFTLYVS
                     WSLISLSSFLKKLSVTCTLQPLVYRKKSMQVIFSIAKKRTFSLPLPRLQIGFPAIFAE
                     KNKRF"
     gene            4613..5365
                     /locus_tag="ACG8LA_002623"
     CDS             4613..5365
                     /locus_tag="ACG8LA_002623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF58 domain-containing protein"
                     /protein_id="HFQ0204886.1"
                     /translation="MILTNKPQEVQLLWQPKERGCHETLTVIFTAYDSLGLFRKSAKR
                     EISFPVTVLPAFCKIQAEKLQRVLEKKQQLNAYQRGLDFREHRAYRPGDSFNRIDWKL
                     SAHTQEWLYREYDYQEEECSPLFCFWGSPSPKFEPLLDLYFSLWHLRKEKQPELLILG
                     NRAFHGKDPGHTYFASLEAGDEKTFFAHLKKYAKKQIVLFVPENSPEVSEAIETLSKD
                     RTVYLVYFVEKQLMVQEKDKICSLPGGEWIDD"
     gene            5355..7526
                     /locus_tag="ACG8LA_002624"
                     /pseudo
     CDS             5355..7526
                     /locus_tag="ACG8LA_002624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343611.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
BASE COUNT         2273 a         1512 c         1372 g         2470 t
ORIGIN      
        1 agaggggggg attttttatc gttgtggaat atttaaatac caacgcttgt catgaaaatc
       61 ttgtgctcca cccttagtat ttccttctgg atcgtttgtc gcacgcatca tgacgtatac
      121 tttcttatta gggaaatcac gcatattgaa agatacatga tagccaacat ttcctaaagt
      181 attataagct tgatttacgt ctggtctata aatcccatca gctcttactc tagctagttc
      241 ttttccagta ttgtagtcca taatgaaaat atactcgtat ttataattag caatgtgcca
      301 tccagctaca tgcaagtttg cgttttcgat ttctccgaac tgatcaatgt gggcgtaatt
      361 tgttccatct gtcagcgtag aatttgcagc acctgctcga gttggatcaa ttactggttt
      421 atcctccgaa gtagttggat tatcatccgt aaaaccatga gccaaatcat aggctagttt
      481 ttctttactt acacctattt cagaaagata accgtaagga tctgtatgat cgccccaaat
      541 attttgtgtt acccataaat gcgatttgat tcctggttgg ttataaggag tgtctaatgt
      601 taatggaata ccatatttca ttgctgaatc tcttgccaat tcaacgtata ctttatagtt
      661 cttttcaaaa gtttctttat catgtgtgtg ttgtaactcg atttgcacag gacttttggc
      721 tcacgaggtt gtcctactct acatcttgct gatagatatg ctgaaaggaa aacaccaaca
      781 ttatgttttg ctttttcagc tagaacgaga caagcaggaa tacctttaga agatatcaaa
      841 ggttttttag gtcataaaga tgtttccact acacaagtct atgcccatat ttctcccgaa
      901 gtgaaaaaaa gatcaatgaa tcaactagaa aactatatag aagagcaaat aaaaaagcac
      961 tcaaattgag tgctttttta agctcactat cactaaaact atcactaatt ttatttataa
     1021 gcgaacatgt ttctatcact gattttttaa atctagcgaa aaacccttat cttaaaggcg
     1081 ttcgttcaat tctttggcaa ggtcttcaaa gcctggcttg cctagaagtg cgaacatggt
     1141 tttcttatag ctcatgtaga aaaattttct tgatgatgat tttatccatc aattgagatt
     1201 gactgttttg ctctcctatg atttcagcta tgattgtccg attttgcggt tttcttctta
     1261 actggtagtt gattttccca gtttccatca actcgctaag catatccacg actccgccaa
     1321 atccggtctt tttcgtaata aaacctagtg ctaccattcg ttcatctaga ttttttgctg
     1381 taatcgtcac accagtaatg agcgagtgct gtaatgtttg ggccagctct tccatccctt
     1441 cagcattgga tacgacggaa gctgttttgt taataggttc ttcgtttatt tcttttggtt
     1501 ctttcctctc cactttcact gtttgacgaa ggacatctag ttcttgcaag agcgtttcgt
     1561 attgttcttg ggtcagcatc acgccagcta ctttttcacg attaaatata tatacgccag
     1621 ttcccgcgtc tcgcgcttga gcaaatacat ccatcggcga tcgtttcact tctgtgatcg
     1681 aagatgtggg aacttctaat ttctttaatt ccaatggatt tcctccttta ctaatcgctt
     1741 tttattatag cacagactga cttgttttga tcttttttcc aaaggtttta tcggtttttg
     1801 cctaaccagt aattgatatc ggtaagaagt ctttcgatac caaatgaagg atggtacaga
     1861 tacgtttttt gatcttcgtt atggtctagt ggaaaaaaat gatcgatgat cactagatct
     1921 gcataccgag gcggcttatt tcgagtacat acatgtatag agatccgttt tcgatgtctt
     1981 agcgttttgt tcagtacccc agcaagtctt cttgcttctt ggtgttcata gcgaaaaaaa
     2041 aagacgattt tcacttcagg agggtggaca tctaaatacc ctcgttcctg gagtgttttc
     2101 agtaaaagca tcccccactc tactgcgggg tgtgcaagtg cttgttggat cgctagccga
     2161 aattgatata gtttatcttt ggaattggga aatttttcta atgtttcctg ataataacga
     2221 acttcttcta tcagccggtc atggatacca attacgtaac gaagtcattc ttggtaaagt
     2281 acttttgtca gctttgattt gctttcgctc tcaaattcgc tattcagcca aaacagcgaa
     2341 tcaagctttt cagtcacaat cgtcaatttc cgatagtctt gtgtctcttc tatccgtttc
     2401 caccgctttt cagtaatctg gttacagctc aagcgcaaaa ttgctagata atttttttct
     2461 tttattggca aaatctgctc ctctctaaat agcaattcag gaaacaattc aaagaatagt
     2521 gttcgactgt ctcctaaaat ctcgatttct gccggatcct ttctttgctt caataattgg
     2581 atgaacatct cagaaaagga ctgctctcca tcatctgcaa aaaaatgcgg aaaatctttc
     2641 aaaaagcaaa acagcagata tcttactttt ctttctgaac caaagatctg tgctttttta
     2701 taagaaaaag aaaggtggta ctcgccaaac cactttctca atcgctcttg cgtagaacga
     2761 tcgtacttct gctcgtaagg ttcattcaat agcagatttt tcagtaaaca aaacgggggt
     2821 gattggatca gaaaaacaaa caagagataa ggttcgctat atccttgatc ataaactaac
     2881 tgaacggttt tcttatgaag aatcagctga atgggacagt cgctttccgc caaacgtttc
     2941 agatgccgat ccactgtttt aacatcgatt ttcagttctt cagctaaatc agcttttcgc
     3001 cagatcaaat ctttcattag attgattagt gaaaataaat tctgtgcatt ttttgataat
     3061 agtttttgcc atctcatcga tcatttctca cctgatttct aaacatattg tttgatcaaa
     3121 atgggttcac tcctaaaaag ataaaaaact ccctttctat ttatttaaat acgcaaatct
     3181 tcctcattat tttttatttt actcaattta atcgtattct catttcaaaa cgaatgtact
     3241 ttaaaaaaac ataataagat cactttgctt gtaggatgta ttcccttcca ttacaatgaa
     3301 ataaatagcg attttatgag aaggtgatgt gaaaatggaa gaaaaaatag aagaatccaa
     3361 acaaaaaatc gatcagttga tataagaatt agaaaaagcg gtcatcggca aacgttcaac
     3421 tatccaattg atgatcgtgg ccctattagc aggtggtcat gtcttattcg aagatattcc
     3481 cggtgtaggt aaaacgttac tggtcaaagc actagcaaaa gctgtacagg gaaccttcag
     3541 cagagtccaa tgtactcctg atctgctgcc tagtgatatt cttggttttt ccgtatacaa
     3601 ttcacaatca aaagagtttg aatttcgtcc gggaccgatc tttaccacga tcttgttagc
     3661 agatgagatc aatcgtacga ctcctcgtac tcagtcagca cttttagaag caatggccga
     3721 gaatcatgca acgatcgaca acaatacata ccctctagac aatcattttt ttgtcttagc
     3781 tacgcaaaat ccaatcgagt acgaaggaac atatcctttg ccggaagcac agctcgatcg
     3841 ttttttattc cgactacaaa tcggttatcc ttcttttgat gacgaacttt tgctactttt
     3901 ggataaattc gaaaaagtgt tggataactt aaatgaagta ttgaacagtt atgaaataga
     3961 agaaataaaa acaaatgtgg cgaatgtctt tgtcagtccc gaagtggcat cttatgcctt
     4021 gcagttagtg tcagcaacaa gaagtcatgc tgccatccag cttggcatca gtccacgagg
     4081 aagcctttcc tttattcagg cagcaaaagc ttatgcttta atccatggga gaaattacgt
     4141 cacgcccaaa gatttgcagg atttagttcc ttacgtgttt tcccatcgcc tgatttttta
     4201 cgatcgttca ttgaaggaag acgaaaagaa acaaatcatt catactcttg ttgcacaaat
     4261 tcctattcct gtgaggtaga ttgaggtaga caatggaaaa aatcaaagat tatttcatta
     4321 attttgtgtt atttctggta tatttcatca ttgtgctttt tgctcttgta ttcaacaatt
     4381 ctttaggctg gttcttgttg gcctttttta ctctttatgt atcatggagc ttgatttcat
     4441 taagcagctt tctaaagaaa ctttcggtta cttgtacatt gcagccactc gtttatcgca
     4501 aaaaaagtat gcaggttatt ttttccatag caaaaaagag aactttttct ttacctctcc
     4561 ctcgtttaca aatcggcttc ccagcaatct ttgcagaaaa aaacaagaga ttttgattct
     4621 tacaaataaa ccgcaagaag tccaattgct ttggcagcca aaagaaagag gatgccatga
     4681 aacattaact gtcattttta cagcctatga tagtctagga cttttcagaa aaagtgcaaa
     4741 aagagagatc tcttttcctg tgactgttct gcctgctttt tgtaagattc aagcagaaaa
     4801 attacagaga gttctggaaa aaaaacagca gctgaacgcg taccaaagag gtcttgattt
     4861 tcgggaacat cgcgcttatc gtccaggtga ttctttcaac cgaatcgatt ggaaattgtc
     4921 tgctcatact caagagtggt tataccgtga atacgattat caagaagaag aatgttctcc
     4981 tcttttttgc ttttggggtt cgcccagtcc aaaatttgaa cctctgctag acttgtattt
     5041 ttctttatgg catttgagaa aagaaaagca gccggaactt ctgatattag gcaaccgcgc
     5101 ctttcatggc aaagaccccg gtcataccta ttttgcttct ttggaagctg gcgatgagaa
     5161 aacttttttc gcacacttga aaaaatatgc aaaaaaacaa atcgtcctct ttgttcctga
     5221 gaattctcct gaagtctcag aagctattga aacattgtca aaagatcgaa cggtttatct
     5281 tgtttatttc gtagaaaaac aactcatggt ccaagaaaaa gacaagatat gttcattgcc
     5341 aggaggtgaa tggattgacg attaaacggg aaaaatggct gcgtggcgtt tactcctttg
     5401 tgatactaag tgtaggtgct ccgatatttg tagtagctaa tcaattgcaa aacagctacc
     5461 ttcttatcct aactattggt gtcctatgcc ttattgtctg ctgtattcct aaaaaatggg
     5521 tacgtttgct gctttctttg ccagtaatga taggttgttt gtttttatat tttccttcga
     5581 agacattttc catattatgg atcttacagt ttttttcgtc agttacagag gaattcttcc
     5641 atctatccca aggtaaactt tattatttgc cagaaaagac agcttttttt ctcataatgt
     5701 tgctgatcta tttatttatt acattgaccg tggattacga ctattggtac gcaccctttc
     5761 tttctttgat ggcttacttc atgatgctta ccgtttttcg gaaaaaagat ttactgtacg
     5821 aaatgattgc ggtagtaact gttttgttcg tgtatctggc agcaaggcaa tttttctcca
     5881 tccggttgtt gtcgagaaac actcgattcc agtcattgac tacagttctg cttatttgtt
     5941 tcttaacttt tagcgctatc ttgcctttat atcttccgaa agtacaccaa tctctcgagg
     6001 aaacgagtga accgatccga gaatatctta atgatgaagg gctttatgac acactccatg
     6061 agtatcaatt aaccggaagt gcaagaacag gcttcagtga gaatgatgaa cagcttggtg
     6121 gacctttata tgataatggc gaagttgttt ttacagcgaa ccaaaaagga aatggctatt
     6181 ggaagatcga aaataaaaat cattacaccg gttctggatg aatagaagat caggacgcac
     6241 ccatccaacc aatccaagaa ttccctgttg acatcacgag ctaccaaacc gttatagaag
     6301 acaaagaaaa cattacattg accctaaaaa aacaagcttt cttaccttat ccttatggaa
     6361 atactacctt gactgatttt tcattagcta gtggacaaac gctttactat ttgcctgaaa
     6421 gccagcgatt cattcctgtc ccgaatgaat cgacacgttc tgcaacttta caaacagaaa
     6481 ggttagtttt tacgagagaa gaattaaaaa gcagtcagtt aaaagctgat gatttagaaa
     6541 atcagcagac aaatcttcaa ttgccaaaaa gtttgcctaa acgtattgag gacttggcgg
     6601 tcgaattgac caaaaatgaa gcaactttaa ttcgtaaagt cgaagctgtc taacagtatt
     6661 taaaaacaag cggaaatttc cgctattcca aaacggatac cgggcatact ccaaaagaac
     6721 acgattatgt ggattatttc ctctttgatt caaaagtcgg ctattgtgac aacttttcaa
     6781 cttctatggt cgtccttctt cgaacacttg gtatcccagc tcgctggaca aaaggtttta
     6841 caaatgggct cagaacaggc acagataatc aagggaatga ggaatacagc attctcaata
     6901 gtcatgctca ttcttggcca gaggtatact ttcctggatt tggctggctt ccatttgaac
     6961 caaccccttc atttgccaat ccaatgggtt cacaaccagt tgctgaaaca accgaaaccg
     7021 tccagcctgc tatcgaacaa ccaaatgaaa gcgaaaatat ggcagaaact atttccagtg
     7081 agagatctga ggtcattcca tcagaagaaa caacactcac accagcttat aaaatcgtct
     7141 tattcagcct tggagtgtgt ttatccgtct tgttgttctt tctattgtta ttcagaaaat
     7201 ctctgcgctg gacaagttat cttatctatc ttcatttttt tgcttctact aatacgattg
     7261 catatcaaaa acttcttaac cctttggaaa cattggtacc gcgcaaaccc gcagaatctt
     7321 tgcaggaata tagcctgcga atagaacaag aattcaagct agatctgcgt ttcattcgat
     7381 taactactca atatgaagca gaaatatatg gacgacaagc agatccggta aaattcgata
     7441 aaaaaaccta tttagaaata acgcatataa taagaaaaac ggtatacaaa aaaattctga
     7501 caaaagggag ccgcttcaaa aaataagata aaatttctgg agaatctact tctcgaatgc
     7561 cgagaaccag ctgattgagt atcgattact cgaaaaaaag gttgtgacac gttttttgtc
     7621 acaacct
//
LOCUS       DAZKKZ010000095         7598 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.098, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000095 DAZKKZ010000000
VERSION     DAZKKZ010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7598)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7598)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7598
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.098"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(135..425)
                     /locus_tag="ACG8LA_002625"
     CDS             complement(135..425)
                     /locus_tag="ACG8LA_002625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204887.1"
                     /translation="MGEKKIKGAGILLVMSKALFLLPCTFMFIVLCYFKRRKKWCWID
                     VLLFLPFFPLIYFLEEIWDDMACDSAFLFSHSLGLMISLTIFAIVLFFLNKK"
     gene            complement(543..803)
                     /locus_tag="ACG8LA_002626"
     CDS             complement(543..803)
                     /locus_tag="ACG8LA_002626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204888.1"
                     /translation="MGVDHLIVLSKLLFWIPFIIMTSAFFYLFKRPNKYLLLSACPMI
                     YFIHKIRGFYYYDSGISLFCYEIGLLASAIFFIFVLEYFRKK"
     gene            complement(940..1353)
                     /locus_tag="ACG8LA_002627"
     CDS             complement(940..1353)
                     /locus_tag="ACG8LA_002627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp20/alpha crystallin family protein"
                     /protein_id="HFQ0204889.1"
                     /translation="MANVPSIRDMFPDFNDVFSPAFNDFLGVSSYPKVDLVENEKEYK
                     LTADMPGCDKEDTTVEYSDNTLTISANHESHTEDKEDGNYVRKERHSVSYKRSFYLPN
                     VDEEKITGTFKNGVLKLVLPKTAYQPKETKKIELN"
     gene            complement(1809..2294)
                     /locus_tag="ACG8LA_002628"
     CDS             complement(1809..2294)
                     /locus_tag="ACG8LA_002628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204890.1"
                     /translation="MHKGIYAGLLGTVILFSACGYKTKNSVKESSAAISTTEVGSTKS
                     TSTTSITNTSTGNVDSQHSQSSIQSFSISSTSEMQESTVPSLPLENSDKALLFLIAHR
                     SELQSDDIVISFYQKIDRDYLFTASSKQIRSQGGSGSVGFYRVSPEGSITMTDANGTP
                     F"
     gene            complement(2433..2648)
                     /locus_tag="ACG8LA_002629"
     CDS             complement(2433..2648)
                     /locus_tag="ACG8LA_002629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF378 domain-containing protein"
                     /protein_id="HFQ0204891.1"
                     /translation="MKTLDAIALTLLIVGGLNWLLVGLFELDLVAMIAGGSTTIFAKI
                     IYIVVGICAIYCLKFFPMITRKVDERY"
     gene            2872..3672
                     /locus_tag="ACG8LA_002630"
     CDS             2872..3672
                     /locus_tag="ACG8LA_002630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HFQ0204892.1"
                     /translation="MSDWLDIAGKVVIVTGGSSGIGRSIVENLLKQNAQVANFDVTEC
                     RIQHENLLSLKVDVSSKTDIEEGIYKVMKHFKTIDGLVNNAGINIPSLLIDRNHPKSK
                     YELSEQVFDKMIAVNQKSVYLMSQAVGRILVQKGSGVIVNLSSESGLEGSEGQSCYAA
                     TKAAMNSFTRSWAKELGKRNVRVVGVAPGILEETGLRTQEYEEALSYTRGISVEQLRN
                     GYSRTSTIPLGRSGKLQEVADLVCYYLSERSSYITGVTTNISGGKTRG"
     gene            3691..5559
                     /locus_tag="ACG8LA_002631"
     CDS             3691..5559
                     /locus_tag="ACG8LA_002631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HFQ0204893.1"
                     /translation="MTLVNRWYQLLKLLVTHKKVSIQEVQKEIKTSNQTIKKDIGELN
                     EEIAGIAKIIQKNKHFELEIYDFDFFDEIMQGKLKTASDFNSASKRIAYLLNRLIETE
                     DFLRMDDLSEEVGVSRGTVVKDLKTLKEMINDFDVKITGTPNKGLRIIGDELELRLLL
                     FYFVSPYFSETKTEQFLEEKQAIKHFQKKTNASKQEITLLTKVIGISLNRISSNYLLK
                     KPINRYSGCFEYIQEFNELINQLEEIYELTLSQYEKDFISFPLNIINTSITMIRKANS
                     DLRLYFDPMMMRIRRLDLIDLDESFLYQEMKQHLSLLINRVIFRYRLTDLFYGEIEKK
                     YPFSYQIASECIQALEAILQHKISKVEISYLTLYLELAFRYQKEHFSSKKVAIVHTTG
                     KGTALMIQRQIKRILGRDIQITHVSEEQYEKVDLNKYFAVFTTIPLKNVNEETPVIHL
                     TNLFDDSWLRAQWQKAKKKRLAGFHSTVFFYQIWKEKKTYQEYLNKLVAPLIRGYYVD
                     EEFEKRILKREYQQSTFVNKEFAFPHTTNQLSQHIVLSVGLITDQGLAETGGNGVIFL
                     FAIPEEMTAEVENELFELYDILFELIKMGIDEFIELAPTQESFLKLIKSKGERLHE"
     gene            5552..6043
                     /locus_tag="ACG8LA_002632"
     CDS             5552..6043
                     /locus_tag="ACG8LA_002632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator GutM"
                     /protein_id="HFQ0204894.1"
                     /translation="MNDMYLFIVFAASAYVLQAVISWKQLKHFNQTYSELRRKGKVAI
                     GKRPGKIRSGTIVMLAIDDHDQVLEVRKMQGVTSLAKFHSLPVYAGEDIHYIDRYHPS
                     VRAEDRLTQAALENAREVYLRIEAGNEKSEQPSLPFIAMLNNFRIWKSTIKEKRSDKR
                     WIS"
     gene            6031..6585
                     /locus_tag="ACG8LA_002633"
     CDS             6031..6585
                     /locus_tag="ACG8LA_002633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HFQ0204895.1"
                     /translation="MDIITKFAEGFMRLFQTGAETFISWMTGIVPVVLMLMVAMNTLI
                     AFLGEDRVTKVAKLSAKNPLTRYLVLPFLSAFMLGNPMSFTMARFLPEYYKPSYYAAQ
                     AQFCHTSNGVFPHINPGELFVWMGIAQGIETLGLNSMELAIRYLLVGLLMNFIGGWIT
                     DFTTGFVCRQQGIVLSKKVELSVD"
     gene            6603..7598
                     /locus_tag="ACG8LA_002634"
     CDS             6603..7598
                     /locus_tag="ACG8LA_002634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HFQ0204896.1"
                     /translation="MYGDIKIVRGNGGYGGPLIIRPTKDKHKFIYVTGGGERPMIVDK
                     IEELTGMESINGFKTSIPDSEIALAIVDCGGTLRCGIYPKKGIPTINIVSTGKSGPLA
                     QYITEDIYVSAVGLEQIQPLMETDDNKETVNTASPDKKYKYDTSKKITEQKAEQQNWI
                     AKIGMGAGKVVATFNQSAREAVDTMIRTVIPFMAFVSLLIGVIQGSGIGNVFANIMAP
                     LAGNAVGLTIIGFICSLPFLSPLLGPGAVISQVIGTLIGVEIGKGNIPPQLALPALFA
                     INTQNACDFIPVGLGLEEAKAETVEVGVPSVLYSRFLNGIPRVIIAWVASFGLYS"
BASE COUNT         2708 a         1213 c         1443 g         2234 t
ORIGIN      
        1 gttactatga ataacataat aagaaagtaa agtggattga tttgagatct ttttatactt
       61 caaaaaagat aacacccaac tttcaaaaat atgttttgga agttgggaca aacgagttaa
      121 tacattttaa tacattattt tttattcaaa aaaaatagca caatggcaaa gatcgtaaga
      181 gagatcataa gccccaatga atgactaaaa agaaaagcag aatcacatgc catatcatcc
      241 catatttctt caagaaaata aataagcggg aaaaagggaa ggaatagtag aacatcgatc
      301 cagcaccatt tttttcttct tttgaaataa cataaaacaa taaacatgaa cgtgcaggga
      361 agtaaaaaca aagctttact cataactaac aaaataccag ctccttttat ttttttctcc
      421 cccacattca aagagtaaca atggtatgta cttaataata gaaaaatgga tcaacttgta
      481 tgaataacag ctgaaaagat ctgcaccaaa taaaaaactt ccagccaaaa ctgactggaa
      541 gtttattttt ttctgaaata ttctaacaca aatatgaaaa agatggccga agctaataag
      601 ccgatttcgt agcaaaacaa tgagatacca gagtcgtaat aataaaatcc tctaatctta
      661 tggataaaat agatcatcgg acaagcagat aagagtaagt atttgttagg ccttttgaat
      721 aagtaaaaga aagcactggt cattatgata aatggtatcc aaaacaaaag tttacttaag
      781 acaatcaaat gatcaactcc catatttttt accaagagag atcataacat ctttatcgta
      841 aaaacaaaat atttttttgc tcattttgaa aatttaaaca tactcgttct tatccaaata
      901 tataaaaatc gcccctcatt catcgagagg cgataagttc taatttaact caattttttt
      961 tgtttctttt ggctgataag ctgttttagg taataccaat ttcagcacac cgtttttaaa
     1021 ggttccagtg attttttctt catcaacatt aggaagatag aatgaacgtt tgtaagagac
     1081 cgaatgtctt tctttccgta catagttgcc atcttcttta tcttctgtat gggactcatg
     1141 attggcggag atcgtcaaag tattatctga atattcaact gtcgtgtctt ctttgtcaca
     1201 gccaggcata tcagcagtta gtttgtattc tttttcattt tcgactaaat ctacttttgg
     1261 ataacttgaa acacctaaaa aatcattgaa tgctggacta aacacgtcat tgaaatcagg
     1321 gaacatgtcg cgaatgctag gtacatttgc catttttgat catcctttca ataagtattt
     1381 tttatttatc cctatttacg taataactct attttgaaaa aaatgcaagt ataatggtta
     1441 gctttgtgaa tatttcatct aatacgatac aaaggctatc tttctaattt gaaaaaggga
     1501 tcattaaaat aataagaaga aaatatgtca aaaggtaaaa aagtaaattc ttctatccaa
     1561 atatagaaaa attgaatcta gaaaaccgcc cgacaataaa tttcattaac tcagttgacc
     1621 gaaaatgaag tagataccaa aaatttatca agagagcaag tagagaagtg agtatattca
     1681 taagagaaat agctgtaacg aattattagg ttaatgcaaa tgcttattta tactccgtat
     1741 aactttctca gaaaaaatga taccaataat gacttgctag tactgtaaat ccgtataata
     1801 tcatctaatc aaaatggtgt tccatttgca tctgtcatcg taatcgatcc ttcgggtgac
     1861 actcgataaa aaccaacgct tccagatcct ccttgggaac ggatttgttt gctggaagct
     1921 gtgaacaaat aatctcgatc aattttttga taaaagctaa taacaatatc gtcactttgt
     1981 aattcggaac ggtgggcaat aagaaataga agtgctttgt cagagttttc taatggaaga
     2041 gaaggtacag tgctttcttg catttcagat gttgaagaaa tgctaaacga ctgaatactt
     2101 gattggctat gttgcgaatc tacattacca gtagaagtat tagtaatgga agtagtagaa
     2161 gtacttttag ttgaaccaac ctcagttgtt gaaatggctg ctgaagattc tttaacagaa
     2221 ttctttgttt tatatccaca ggcagaaaaa agtattacag ttcccaacaa gcctgcgtaa
     2281 atccctttat gcatgatagc tcctcctaaa atagattatc tttattcagt atatcactta
     2341 aacaaagaaa agcagatggt ttaaaatgaa aaaaccttcc caataaaggg aaggttcatg
     2401 aagataataa cttttttaat aattatagct ttctaatatc tttcatcaac ttttctagta
     2461 atcattggga aaaatttcaa gcagtagatc gcacaaatac ctacgacgat ataaatgatc
     2521 ttcgcaaaaa tagttgttga accaccagca atcatagcta ctaaatcaag ttcgaacaag
     2581 cctaccaaca gccagttcaa ccctcccaca atcaataaag ttaatgcaat agcatctaaa
     2641 gttttcatta gaattctcct ttcttaaatg ataaaacaat tatatatcaa aaagagaaac
     2701 attgcttata taacgctcag gaattttagc aatctatgca aaaagatgaa aatttttttt
     2761 gctcttccat tagtacacat tttttagctg aagctgtaaa tttcatgtct taattttttt
     2821 tagtgagctt ttatactgga tttgtaagaa aaaagaagga gaggatcaca tatgtcggat
     2881 tggttggata ttgcaggaaa agtagtaatt gtaactggag gttcctcagg aattggaaga
     2941 agtatcgtcg aaaatttgtt gaagcagaat gcacaagtag cgaattttga tgtaactgaa
     3001 tgccgtatac agcatgaaaa cctactatct ttaaaagtcg atgtgtcttc taaaacggac
     3061 atagaagaag ggatatataa agtaatgaaa catttcaaga cgatcgatgg tctagtcaat
     3121 aatgcaggaa taaatattcc ttctcttcta atagatagaa atcatccaaa aagcaagtat
     3181 gaattatcag aacaagtttt tgataagatg atcgctgtca atcaaaaaag tgtatatttg
     3241 atgagccaag cagttggaag aatcttggtg caaaagggat caggagtgat cgtgaatctt
     3301 tcttctgaat caggattgga aggatcagaa ggacagagct gttatgctgc tacaaaagca
     3361 gcgatgaaca gttttactcg ttcttgggca aaagagttag gaaagaggaa tgttcgtgtg
     3421 gtaggtgttg caccagggat actggaagaa accggtttga gaacacaaga atatgaagaa
     3481 gctctttctt atacgagagg tataagcgtc gaacagctga gaaacggtta cagtcgaaca
     3541 agtacgatcc ctctaggaag gagtggtaag ctgcaagaag tggcggatct agtctgctat
     3601 tatctttcag aaagatcaag ttatatcact ggagtcacga ctaatatttc aggaggtaaa
     3661 acaagaggat aaaggatagg ggggacgcac gtgacgctag taaacagatg gtaccaatta
     3721 ttgaaattac tagtcactca caagaaagtt tcaatccagg aagtgcaaaa agaaatcaaa
     3781 accagtaatc aaaccataaa aaaagatatt ggggagttga atgaagaaat tgccggtatt
     3841 gcaaaaatca tccaaaaaaa caaacatttt gaacttgaaa tttatgattt tgattttttt
     3901 gatgagatca tgcaaggaaa attgaaaaca gccagtgatt tcaattcggc atccaaaaga
     3961 atcgcttatt tactaaatag gctgatcgaa acagaggatt tcttacgtat ggatgatttg
     4021 tctgaagaag tcggtgtcag cagaggaaca gtggtcaagg atctaaagac attaaaagag
     4081 atgatcaatg attttgatgt aaagattaca ggcacaccaa ataaaggact aagaataata
     4141 ggagatgagc tagaattacg actactttta ttttattttg tttctcccta cttttcagag
     4201 acgaaaacag aacagtttct agaagaaaaa caagcaatca aacattttca gaagaagacg
     4261 aatgctagta aacaagaaat caccctttta acgaaagtta tcggtatttc tttgaataga
     4321 atctctagta actatctgtt gaagaagccc atcaatcgtt acagtgggtg ttttgaatat
     4381 atccaagaat tcaatgaact gatcaatcag ttggaagaaa tctatgaact aactttgagc
     4441 caatatgaaa aagattttat cagttttcct ttgaacatca tcaacacaag tataacgatg
     4501 ataaggaaag ctaactctga tttgcgctta tatttcgacc ccatgatgat gcgtattcga
     4561 cgattagatc tcattgatct ggatgagtcc ttcttatatc aagagatgaa acagcacctc
     4621 tctttattga taaatcgggt aatttttcgt tatcgattga ctgatttatt ttatggtgag
     4681 atagaaaaaa agtatccttt ttcttaccaa atcgctagcg aatgcataca agcattagaa
     4741 gctatcttgc aacataagat ctctaaagta gagatcagct acctaacgtt gtatttggag
     4801 ttagcatttc gatatcaaaa agagcatttt tcctctaaaa aagtagccat tgttcatacg
     4861 acaggaaaag gaacagcatt aatgatccaa agacaaatca aaaggatatt ggggagggat
     4921 atacaaataa cacatgtttc agaagaacaa tatgaaaaag tagatctaaa caaatatttc
     4981 gctgttttta caacgattcc gttaaaaaat gtaaatgaag agacaccggt gatccatttg
     5041 actaatcttt ttgatgactc ttggttaagg gcacaatggc aaaaagcaaa aaaaaagcga
     5101 ttagccgggt ttcattctac tgtttttttc tatcaaatat ggaaagaaaa aaagacgtat
     5161 caagaatatt taaacaaatt agtcgctcct ttgatcagag gctattatgt ggatgaagaa
     5221 tttgaaaaaa ggatcttgaa aagagaatat cagcaaagca catttgttaa caaagaattt
     5281 gcttttcctc acacaaccaa ccagctatct caacacattg ttttatcagt agggctaata
     5341 actgatcaag gtttagcaga aacaggagga aatggagtta tttttttatt tgccatacct
     5401 gaagaaatga cggctgaagt tgagaatgaa ttatttgagc tatacgatat cctatttgaa
     5461 ctcataaaaa tgggaataga tgagtttatt gaattagcac cgacacaaga atcattttta
     5521 aaactaatca aaagtaaagg agagagactt catgaatgat atgtatctat tcatagtttt
     5581 cgcagcttca gcttatgtgc tgcaagcagt tatcagttgg aagcaactaa agcatttcaa
     5641 tcaaacatat agcgaactgc gaagaaaagg aaaagtagcg attggtaaac gacctgggaa
     5701 aatccgttca ggcacgattg ttatgctagc tatagacgat catgatcaag ttttagaagt
     5761 cagaaaaatg caaggggtta catctttggc aaaatttcat tcattacctg tctatgcggg
     5821 tgaagatatc cattacatcg atcgttacca tccctcagtt cgagcggaag atcgtttgac
     5881 acaagcagct ttagaaaatg ccagagaagt atacttacga atagaggcag gaaatgaaaa
     5941 aagtgaacaa ccttcattgc cttttattgc tatgctcaat aattttcgga tatggaaaag
     6001 tacgatcaaa gaaaaaagga gtgacaaacg atggatatca taacaaaatt tgctgaggga
     6061 tttatgaggc tgttccaaac aggtgcagaa acattcataa gctggatgac aggaatcgta
     6121 ccagttgtct tgatgctgat ggttgcaatg aatacgctga ttgctttttt aggtgaagac
     6181 cgagtaacga aagtagccaa attatcagcg aaaaatccgc ttactcgtta ccttgtgtta
     6241 ccgttcttat ctgcttttat gttgggaaat cctatgtcat ttacaatggc tcgtttcctt
     6301 ccagaatact acaaaccaag ctattatgct gctcaagctc aattttgtca tacgagcaat
     6361 ggtgtattcc cccatattaa tcctggagaa ttgtttgtat ggatggggat tgctcaaggg
     6421 atcgaaacct tagggctaaa ttcgatggag ctggctatcc gatacttgct tgtgggactg
     6481 ctgatgaact ttattggtgg ttggataact gattttacta ctggatttgt atgcagacag
     6541 caaggaatcg ttcttagcaa aaaagtagag ctttcagttg attagagaaa ggagagtttt
     6601 aaatgtatgg tgatattaag atcgtaagag gaaacggcgg gtatggaggt cctttgatta
     6661 ttaggccgac aaaagataaa cacaagttca tctatgtcac aggtggaggt gagaggccaa
     6721 tgatcgtaga taaaatagaa gaactgacag gtatggagtc tatcaatggg ttcaaaacat
     6781 caatacctga tagtgaaatc gcgcttgcaa tcgttgactg tggagggact cttagatgtg
     6841 gaatttatcc taaaaaaggg ataccaacca tcaatatcgt ttccacagga aaaagtggcc
     6901 cattagcaca atatatcact gaagatattt atgtttcagc agtagggtta gaacaaatac
     6961 agccactaat ggaaactgat gataacaaag aaacagtaaa tactgcatct ccagataaaa
     7021 agtacaaata tgatacttct aaaaagataa ccgagcaaaa agcagagcag caaaactgga
     7081 tagcaaaaat tggaatgggc gcgggaaaag tagttgctac attcaatcaa tcagcaagag
     7141 aagcagtaga tacgatgatc cggacagtga tcccttttat ggctttcgtt tcccttttga
     7201 ttggtgtgat acaaggttct gggatcggta atgtatttgc taacattatg gcacctttag
     7261 caggaaatgc agttggatta acaatcattg gctttatttg ttcactgcca tttttatctc
     7321 ctttgcttgg tccaggggca gttattagcc aagtgattgg aacattgatc ggtgtagaga
     7381 ttgggaaagg aaatattcct ccccaattag cattaccggc actatttgct atcaatactc
     7441 aaaatgcatg tgattttatt ccagtcggtc taggtttgga agaagcaaaa gctgagacag
     7501 tagaagtagg tgtaccatca gttctttatt caagatttct taacggcatc ccacgagtta
     7561 tcattgcttg ggtagcaagt tttggattat atagctga
//
LOCUS       DAZKKZ010000096         7577 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.099, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000096 DAZKKZ010000000
VERSION     DAZKKZ010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7577)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7577)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7577
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.099"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            73..1245
                     /locus_tag="ACG8LA_002635"
     CDS             73..1245
                     /locus_tag="ACG8LA_002635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS1542 family transposase"
                     /protein_id="HFQ0204897.1"
                     /translation="MTQVHFTLNNEEVQSIIEHSVKDDVSKNILTTVFNQLMENQRTE
                     YIQADDYERSESRQSQRNGYYERDFTTRVGTLELKVPRTRDGEFSPTVFERYQRNEKA
                     LLASMLEMYVSGVSTRKVSKIVEELCGKSVSKSFVSSLTEQLDPMVNEWQNRSLSGTN
                     YPYLMTDVLYIKVREDHRVLSKSCHIAIGITEGGDREIIGFMIQNEESDDTWSIFFEY
                     LKERGLKGTELIISDAHKGLVSAIRKSFTNASWQRCQVHFLRNIFSSIPKKNSKPFRE
                     AVKAIFKFTDIELARTAKNALVGEYIDQPKYTKACEILDNGFEDAFQYTVIGNSHNRL
                     KSTNLLERLNQEVRRREKIIRIFPNRTSANRLIGAVLMDLHDEWLSSTRKYIKFDQ"
     gene            1532..2857
                     /locus_tag="ACG8LA_002636"
     CDS             1532..2857
                     /locus_tag="ACG8LA_002636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HFQ0204898.1"
                     /translation="MMDYSKEPVNDYFLIDMKSFYASVECIERNLDPLTTELVVMSRA
                     DNTGSGLILASSPAAKKKYGISNVSRPRDLPQPFPKTLHVVPPRMNLYIKRNMQVNNI
                     FRRYVADEDLLIYSIDESILKVTRSMNLFTTEGTRSQRRKKLAQMIQENIKEELGLLA
                     TVGVGDNPLLAKLALDNEAKHNDGFLAEWTYQNVPDKVWNIPEMTDLWGIGSRMKKRL
                     NQIGIMSIKDLANWNPYTIKSHLGVIGLQLYFHANGIDRTDIAIPPEPTKEKSYGNSQ
                     VLPRDYTRRNEIELVVKEMAEQVAIRIRQHNCKTGCVHLYIGTSILETRPGFSHQMKI
                     PITDNTKELQNYCLFLFDKYYEGQEVRHVGITYSKLVYTDSLQLDLFSDPQKQIDEEN
                     LDKIIDKIRQKYGFTSIVHASSMLEGARSITRSTLVGGHAGGAGGLKND"
     gene            2850..3200
                     /locus_tag="ACG8LA_002637"
     CDS             2850..3200
                     /locus_tag="ACG8LA_002637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204899.1"
                     /translation="MIDYNDRGRLKWAGFYLSDHTEKIDADNEQRANQNLAKEQMTTE
                     EVAEVLNAAVIKNRSVCIQKEERNAEGYYPEDIVSKILGSDELGIYVGKNKVHYDEIR
                     HIEFYQDNKWGRLE"
     gene            3197..3367
                     /locus_tag="ACG8LA_002638"
     CDS             3197..3367
                     /locus_tag="ACG8LA_002638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204900.1"
                     /translation="MNIIQQYELKYITFDQLSEEIWGYGQRLINEVGVERFSFYVEAA
                     AGYHKYEYYIGY"
     gene            complement(4271..4546)
                     /gene="prgO"
                     /locus_tag="ACG8LA_002639"
     CDS             complement(4271..4546)
                     /gene="prgO"
                     /locus_tag="ACG8LA_002639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA segregation protein PrgO"
                     /protein_id="HFQ0204901.1"
                     /translation="MALLPTNKDKKKIGAEDISIKDDINVELGERKYTAKERKPVQVD
                     PPVLKTIRDLSYAKDIPMYEIVKLAMDAYVDTLNDEERIIYNRRSKD"
     gene            complement(4518..5471)
                     /locus_tag="ACG8LA_002640"
     CDS             complement(4518..5471)
                     /locus_tag="ACG8LA_002640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFQ0204902.1"
                     /translation="MENLRTAFKTSDKLGKVVMLTGRKGGIGKTTDNDLLAIVSSQLF
                     EKDVLLIDYDQQRNTTSNIGSTYQITSFDRSMSAAIKKGDWVSGITQVSPHLYIMAGS
                     PGSEELNEYLSEKYPDRRKRSLAFIKPLEELRKNFDYIFIDCPPSTDNVVRAFLTAAD
                     YIIAMQELKRYAMEGTEDFINKVLVPIVTNFEESHLQIIGILPVLFSVRRSSQHANYQ
                     KTIDKYGESNIFKSIVKGSDRLEMYGENGIQLNDYVDRRWWAIFADIFTELEERIEYY
                     EQHGDIEGFDYTPKYADSMANHILPLGKEIKLNGIITNEQR"
     gene            6083..7576
                     /locus_tag="ACG8LA_002641"
     CDS             6083..7576
                     /locus_tag="ACG8LA_002641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000947690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primase C-terminal domain-containing protein"
                     /protein_id="HFQ0204903.1"
                     /translation="MLSEIYSAILKNGLRTYKYRNSTMKPAGHIDSSRSGAIFAYRSK
                     QLMNVGRGMVITSEEAILENEKKLTHWTPNTYRFGTYADDYRTVVKGHSEKNLSQINT
                     FVVDIDSKENHQGEIILACLDQVGYMPTLILESDHGYQVYFVLKTPGYVTKKSNFKVI
                     DVAKKISKTIRLQLAEKLSGVDLGCNHFGIARFPQENNIVFKEMNYQYSFADWIQWSM
                     KLESDQKTKEDRERKLIVFPEKKEIRQVDEPWFDMLLHKANIVGGEGRLGRNNVIFTL
                     SLAYYSSGYALDTCEYNMFTFNERLQEPLSEAELVKIVRSAYSGNYQAASREFIIELC
                     QQWVSPTLKNNDLFIQRRGWWKFKKPRDQRKYSHKNEWKEDLLAYLSEKSLASEPYLN
                     LSKKELASQLTMPKRTLDKILNELREENKVFYKVTRGRNGGMIIASVKTLFARVIQLS
                     KEKRLDYSTRITEVFGLNESLVEETFRQLSTPLNPLKEVNLFEVDTG"
BASE COUNT         2607 a         1274 c         1406 g         2290 t
ORIGIN      
        1 taaaaggcca tgtaacagcc cttttacggt acaatgtttt taaccacaaa aacataccca
       61 ggaggacgtt acatgaccca agtacatttt acactgaaca acgaagaggt tcaaagtatt
      121 attgaacatt cggtaaaaga tgatgtttct aaaaatattt taaccactgt tttcaaccaa
      181 ttgatggaaa atcaacgaac agaatatatt caagccgatg actatgaacg ttcagaaagt
      241 cgtcagagtc aaagaaatgg ctattatgag cgagacttta cgactcgtgt gggtacactc
      301 gaattaaaag tgcctagaac acgtgatggt gaattttcac cgacggtgtt tgagcgttat
      361 cagcgaaatg aaaaggcact gctcgcttca atgcttgaga tgtatgtttc gggcgtttcg
      421 acacgtaaag tttcaaagat tgttgaagag ctatgtggaa aatctgtatc gaaatctttt
      481 gtttctagcc tgactgagca gttagacccg atggtcaacg aatggcagaa ccgttcactc
      541 tcaggtacga attatcctta tctgatgact gatgttctct acataaaagt ccgtgaggac
      601 catcgagtgc tttctaaaag ctgccatatt gcgatcggga taacagaagg tggcgaccgt
      661 gaaatcattg gcttcatgat tcaaaatgaa gaaagtgatg acacatggtc catcttcttt
      721 gaatacttaa aagaacgcgg cctaaagggg acagaactca tcatttctga tgcccataaa
      781 ggcctagtgt ctgcgattcg taagtcattt accaacgcaa gttggcagag atgccaggtc
      841 cattttttaa gaaacatctt cagttccatt ccaaaaaaga attcaaaacc gtttagagaa
      901 gcagtaaaag cgatctttaa gtttacggat attgaactcg ctcgaacagc taagaatgcc
      961 ttagtcggtg aatatatcga ccagcctaaa tatacaaaag cctgcgaaat attggataat
     1021 ggcttcgaag atgcctttca atacacggtt atcggaaata gtcataatcg gctaaaaagc
     1081 accaaccttc ttgaacgact gaaccaggaa gtccgcagaa gagaaaagat tattcggatt
     1141 tttcccaacc gaacgtctgc caatcgatta attggagctg tccttatgga ccttcatgac
     1201 gaatggctca gttctacaag aaaatatatt aagtttgatc aatgagagac cggtaaaaca
     1261 ttgtatagta ttttacacag gattatggac ttgacttatt tttttctaat ataactaagc
     1321 aaaactggat aatacgacac ttattttcaa attttcacaa gactaatagt aaatatccat
     1381 ttaataaagt gatacaatgt gttgatttta caaatcaaca gaagaagtag ggaaataact
     1441 tacctatgct tctttttttg tacatttaat cgattcttct ttacaaaaac gaacgtatgt
     1501 ttgtataatg tggaagaatg gagtgttatt tatgatggat tattcaaaag agccagtaaa
     1561 tgattacttt ttgatcgata tgaaaagctt ttacgcaagt gtcgaatgta tagaaaggaa
     1621 tttagatcca ttaacgactg aattagtcgt catgagtcga gcggataata caggatcagg
     1681 gttgatttta gcttcttcac cagctgcaaa gaagaagtac ggtatttcta atgtcagtcg
     1741 accacgagat ctaccgcaac cttttcctaa aacgttacat gtcgttccac cacgcatgaa
     1801 tctctatatt aagcgaaata tgcaggtaaa caatattttc agaaggtatg tagcagacga
     1861 agatttattg atttactcga tcgatgaatc gatcttaaaa gtgaccagat caatgaatct
     1921 ttttacgact gaaggaacaa gaagtcaacg gagaaagaag ctggctcaaa tgatccagga
     1981 gaatattaaa gaagagctag gattgcttgc tacagtaggt gtcggagata atcccttatt
     2041 agctaaactt gctttagaca atgaagcaaa acataatgat ggattccttg ctgaatggac
     2101 gtatcaaaat gttcctgata aagtatggaa tattcctgaa atgacagacc tttggggtat
     2161 tggatctcga atgaaaaaaa gactcaacca aattggtatc atgagtatta aagacttagc
     2221 taattggaat ccatacacta ttaagagcca tttaggtgtg attggcttac agctgtattt
     2281 tcatgcgaac gggatcgatc gaacagatat agcgatccca ccagaaccga caaaggaaaa
     2341 atcatatggt aattcacaag tgttaccacg agattatacc aggagaaatg aaatcgaact
     2401 ggtggtaaaa gaaatggcgg aacaagtagc tattcgtatc aggcaacata actgtaaaac
     2461 aggttgtgtc catttataca ttggcacgtc gatcttagaa acgagaccag gtttttcaca
     2521 ccagatgaag atccctataa cagataatac aaaggaattg cagaattact gtcttttctt
     2581 gtttgataag tattatgaag gacaagaagt aaggcacgtt ggaataacct atagcaagct
     2641 tgtgtacact gattcgcttc agctggattt atttagtgat ccacaaaagc aaattgacga
     2701 agaaaattta gataaaatta ttgacaagat tcggcaaaaa tatggtttta cgtcgattgt
     2761 acatgcttct tctatgttag aaggcgctcg tagtattact agaagtacat tggttggtgg
     2821 ccatgcaggc ggcgcaggag ggcttaaaaa tgattgatta taatgatcgt ggacgtttaa
     2881 agtgggcagg tttttattta tctgatcata ctgaaaaaat tgatgccgac aatgaacaac
     2941 gagccaatca aaatttggca aaagaacaaa tgacgactga agaggttgcg gaagtattga
     3001 acgctgcagt cataaaaaat agatcagtat gtattcaaaa agaagaacga aacgctgaag
     3061 gatactatcc agaagatatt gttagcaaga tcttaggtag tgatgagctg gggatctacg
     3121 ttggaaaaaa caaagttcac tacgacgaaa tacgtcatat cgaattttac caggataata
     3181 aatggggtcg attagaatga acattatcca gcaatatgag ctaaagtata taacctttga
     3241 tcagctatca gaagagattt ggggttatgg ccagcgtttg ataaatgagg ttggtgttga
     3301 acgcttctct ttctatgtag aagctgcagc aggataccat aaatacgaat actatattgg
     3361 ctattaaagt gcaataaaat tatatttctt ttatgtttta cattttgtat caattctgat
     3421 aaaattacct ataggtaatt aaaaaatata aaaaaactag ttacaacctt aggacgttgt
     3481 aactagcttg aagcatacta gagctaacta aaatagcact agaaagcaat gttaaacccg
     3541 tccaacaaac ttgatttaac attgagacca gcttattcag ctaaatatag ttgaataagc
     3601 ttcttttgtt ttaaaaaaac aaaaggtgta ctacgaataa cgcaagtaaa agaaatacta
     3661 ttacaaccag taggctacaa gtaagtatta ctaaacattg cgtagttaga acctttgctc
     3721 tattgtctaa agccacaaaa ttagagatca gctttatgat gctaagagcg agctgcatcc
     3781 atgcggacat aggttctttt gacactatta attctccttt ttaggataag ggaaattgct
     3841 agtagttttt tcattagcac catccccctt catttgattg agtctagtgc tgctgtgata
     3901 gtttgctgtt taatatgctt acattcttat tataacataa atgaaacaaa cacatggtta
     3961 gaggtcgtat caatcaaaat agtgtctcac aaacgattta ttacttactc ctgctgacta
     4021 acggactgtt cttcagtaac tgtaactata tgtttgttaa aaccaccatt acctgtagat
     4081 aaaaaccaat atatttacta tactcactat attaaatata tttagtatag taaaaactag
     4141 aaacaataaa atttgtgaat gttgtatacc cccaaacaat acacatattt tgaaggatta
     4201 ggattaataa agctaaaaat atagtaagta tactaaatat atttactata tctagtatac
     4261 ttactatatt ttaatctttt gatcgtctat tatatataat ccgttcctcg tcgtttaaag
     4321 tatcaacata ggcgtccatt gcaagtttga ctatttcata cataggaata tcttttgcat
     4381 aactaagatc ccgaatggtt tttagtacgg gaggatctac ttgaactggt tttctttctt
     4441 tcgcagtgta ctttcgttcc cctaactcga cattaatatc atctttaatt gaaatatctt
     4501 cagcaccaat tttcttctta tctttgttcg ttggtaataa tgccatttag tttaatctcc
     4561 tttccaagag gtaggatatg attggccatt gagtcagcat atttaggtgt ataatcaaat
     4621 ccttcaatat caccatgttg ttcatagtat tcaattcttt cttctaattc tgtaaagatg
     4681 tctgcaaaaa tagcccacca tcttcgatct acataatcat ttaattggat accattctca
     4741 ccatacattt ctaaccgatc cgagccttta acaatgcttt taaaaatgtt tgattcacca
     4801 tacttatcaa ttgttttttg atagtttgcg tgttgagagg aacgtcgcac tgagaaaaga
     4861 acaggcaaaa ttccaatgat ttgaagatga gactcttcaa aattcgtgac aatcggaact
     4921 aaaactttat taataaaatc ttctgttcct tccattgcgt accgttttaa ttcttgcatt
     4981 gcaataatat aatctgcagc agttaagaat gcacgaacca cattatctgt tgatggtggg
     5041 cagtcgataa agatataatc gaaatttttt ctcaattctt ctaaaggttt aatgaaggcc
     5101 aatgatctct tacgacgatc aggatatttt tcggacaagt attcattaag ttcttcagat
     5161 ccaggagagc cagccataat atataaatgt ggacttactt gagtaatacc tgaaacccag
     5221 tccccttttt tgattgctgc agacatggat cgatcaaagc tagtaatttg atacgttgat
     5281 ccaatgttgg aagtagtatt tctttgttgg tcataatcaa ttagcaacac gtctttttca
     5341 aaaagttgac tagaaacaat cgctaataaa tcattgtctg tagtcttacc aatgccgcct
     5401 tttctacctg taagcattac aacttttcct agtttatctg atgttttaaa tgcagtccgt
     5461 aagttttcca tagttccctc caatttccta tactaaatat atttagtata cttcatatac
     5521 ttaatatatt cgatatatct aatatactcc aaattgataa gaattcagac tttataagga
     5581 atatagtgga tatactaaat atatttgcta tattcagtat atcagatata ttcaaaatgt
     5641 caaaatatat ttgtgcgttt tgcgttgaca atttagagtg aaaagaggta aacttaattc
     5701 tatagaaacc acagataatt cactatttac aaagtagcaa aagcagtggt actctttaaa
     5761 cagaaaaatt acataaaaaa aagagacgga aataattgat tttagcagaa tcaattattt
     5821 ctgaatcaca tggttaggac atgtgttcac gctcgtctca agaatatgta agtagctacc
     5881 aactacttat attaaaagtt gatcggatac cttttccgat tgcctttatt ctaccaaaaa
     5941 aaggcgagca actcaacaga agaacgttta tttagtgtac ttaaattaaa tattcttaaa
     6001 cactgaagag agaacacata ctatggctga gattaaagct aaactgtgtt ctctttttgt
     6061 ttgagaaagg acgttacaat cgatgttgag cgaaatttat tcagctattc ttaaaaacgg
     6121 cttacgtaca tacaaatatc gaaacagcac catgaaacct gcaggtcata ttgattccag
     6181 taggagtggt gctatctttg cgtaccgtag caagcaatta atgaatgttg ggcgtggtat
     6241 ggtcattact tcggaagaag ctattttaga gaacgaaaag aaactaacgc attggacacc
     6301 taatacctat cgctttggta cttatgcgga tgattatcga acagtggtta aaggtcattc
     6361 tgagaaaaac ttaagtcaaa tcaacacatt tgtagttgat atcgattcaa aagagaacca
     6421 tcaaggcgaa attattttag cctgtttaga tcaagtgggc tacatgccaa cgctaatttt
     6481 agaatcagat catggttatc aagtttattt tgtactaaag acaccaggct atgtcacaaa
     6541 gaaaagcaat ttcaaggtga tcgatgtagc aaaaaaaatt tcaaaaacaa ttcgtctaca
     6601 gttggctgaa aaattgtccg gagtggatct aggatgtaac cacttcggaa ttgctcgatt
     6661 cccacaagaa aataatattg tttttaaaga aatgaactat cagtattctt ttgctgactg
     6721 gattcaatgg tcgatgaagc ttgaatcaga tcaaaaaaca aaagaagatc gagaacgaaa
     6781 actaattgtc tttcctgaga aaaaagaaat tcgtcaagta gatgaaccgt ggttcgatat
     6841 gttacttcat aaagcaaaca tcgtcggcgg agaaggacgt cttggtcgaa ataatgtgat
     6901 tttcacgctt tctttagctt attactcttc aggttatgca ttggatactt gcgaatacaa
     6961 tatgttcaca ttcaacgaac ggttacagga accgctatct gaagcagaat tagtaaagat
     7021 tgtacgtagt gcttattctg gtaattatca agcagcaagc agagaattca ttattgaatt
     7081 gtgccagcaa tgggtttcac caaccttaaa aaataatgat ctgttcattc aacgacgtgg
     7141 ctggtggaaa tttaaaaagc cacgagatca aagaaaatat agtcataaaa atgaatggaa
     7201 agaagatcta ttggcttatc taagcgaaaa aagtcttgct agtgagcctt atttgaacct
     7261 gtcaaaaaaa gaattggctt cacaactaac gatgcccaag cgaacacttg ataagatctt
     7321 aaatgagtta cgagaggaga ataaagtctt ctacaaggta acacgaggaa gaaatggcgg
     7381 aatgatcatt gcttcagtca aaacgttgtt cgcgagggtt attcaactaa gtaaagaaaa
     7441 gagactagat tattcaacaa ggatcacaga ggtatttgga ctcaacgaga gcttagtaga
     7501 agagacattt agacaattat caaccccctt gaaccctctt aaagaagtga atctttttga
     7561 agtagataca ggttgaa
//
LOCUS       DAZKKZ010000097         7366 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.100, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000097 DAZKKZ010000000
VERSION     DAZKKZ010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7366)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7366)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7366
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.100"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..689
                     /locus_tag="ACG8LA_002642"
     CDS             <1..689
                     /locus_tag="ACG8LA_002642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015543625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="primase C-terminal domain-containing protein"
                     /protein_id="HFQ0204904.1"
                     /translation="RNNVMFTLSLAYFSSGYSIETCEYNMFEFNNRLDQPLEEKEVIK
                     IVRSAYSENYQGANREYITILCKAWVSSDLTSKDLFVRQGWFKFKKKRSERQRVHLSE
                     WKEDLMAYISEKSDVYKPYLVTTKKEIREVLGIPERTLDKLLKVLKANQEIFFKIKPG
                     RNGGIQLASVKSLLLSIIKVKKEEKESYIKALTNSFDLEHTFIQETLNKLAERPKTDT
                     QLDLFSYDTG"
     gene            1037..1207
                     /locus_tag="ACG8LA_002643"
     CDS             1037..1207
                     /locus_tag="ACG8LA_002643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204905.1"
                     /translation="MKKFIYRVLENDEVVAIFNEQQYAQDFIAYEKTISDKQFEIEKV
                     DIADWLLQPREF"
     gene            1221..1838
                     /locus_tag="ACG8LA_002644"
     CDS             1221..1838
                     /locus_tag="ACG8LA_002644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFQ0204906.1"
                     /translation="MAKIGYARVSSKEQNLDRQLQALQGVSKVFSDKLSGQSVERPQL
                     QAMLNYIREGDIVIVTELDRLGRNNKELTELMNQIQIKGATLEVLNLPSMNGIEDENL
                     RRLINSLVIELYKYQAESERKKIKERQAQGIEIAKKKGKFKGRQHKFKENDPRLKHAF
                     DLFLNGLSDKEVEEQTGINRRTFRRYRARYNVTVDQRKNNEKRDS"
     gene            1838..2776
                     /locus_tag="ACG8LA_002645"
                     /pseudo
     CDS             1838..2776
                     /locus_tag="ACG8LA_002645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase"
     gene            complement(3469..4116)
                     /locus_tag="ACG8LA_002646"
     CDS             complement(3469..4116)
                     /locus_tag="ACG8LA_002646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type A-7 chloramphenicol O-acetyltransferase"
                     /protein_id="HFQ0204907.1"
                     /translation="MTFNIIELENWDRKEYFEHYFNQQTTYSITKEIDITLFKDMIKK
                     KGYEIYPSLIYAIMEVVNKNKVFRTGINSENKLGYWDKLNPLYTVFNKQTEKFTNIWT
                     ESDKNFISFYNNYKNDLLEYKDKEEMFPKKPIPENTIPISMIPWIDFSSFNLNIGNNS
                     SFLLPIITIGKFYSENNKIYIPVALQLHHSVCDGYHASLFMNEFQDIIHRVDDWI"
     gene            complement(4246..5184)
                     /locus_tag="ACG8LA_002647"
     CDS             complement(4246..5184)
                     /locus_tag="ACG8LA_002647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HFQ0204908.1"
                     /translation="MKKIDEKLAAEISLKKPAVSNSRLSNSRLSGQTLGKSQPALSFD
                     AMTIVGNLNKTNAKKLSDFMSVEPQIRLWDILQTKFKAKALQEKVYIEYDKVKADTWD
                     RRNMRVEFNPNKLTHEEMIWLKQNIIDYMEDDGFTRLDLAFDFEDDLSDYYAMTDKAV
                     KKTVFYGRNGKPETKYFGVRDSDRFIRIYNKKQERKDNADVEVVSEHLWRVEVELKRD
                     MVDYWNDCFNDLHILKPAWATLEKINEQAMVYTLLHEESMWGKLSKNTKTKFKKLIRE
                     ISPIDLTELMKSTLKANEKQLQKQIDFWQREFRFWK"
     gene            5675..6892
                     /locus_tag="ACG8LA_002648"
                     /pseudo
     CDS             5675..6892
                     /locus_tag="ACG8LA_002648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase"
     gene            7026..7265
                     /locus_tag="ACG8LA_002649"
     CDS             7026..7265
                     /locus_tag="ACG8LA_002649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002425012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
                     /protein_id="HFQ0204909.1"
                     /translation="MIVGNLGAQKEKRNDTPISAKKDIMGDKTVRVRADLHHIIKIET
                     AKNGGNVKEVMEIRLRSKLKSVLIVHYLKILYNRN"
BASE COUNT         2677 a         1152 c         1259 g         2278 t
ORIGIN      
        1 ggcgtaataa cgtcatgttt accctctctt tagcctactt tagttcaggc tattcaatcg
       61 aaacgtgcga atataatatg tttgagttta ataatcgatt agatcaaccc ttagaagaaa
      121 aagaagtaat caaaattgtt agaagtgcct attcagaaaa ctatcaaggg gctaataggg
      181 aatacattac cattctttgc aaagcttggg tatcaagtga tttaaccagt aaagatttat
      241 ttgtccgtca agggtggttt aaattcaaga aaaaaagaag cgaacgtcaa cgtgttcatt
      301 tgtcagaatg gaaagaagat ttaatggctt atattagcga aaaaagcgat gtatacaagc
      361 cttatttagt gacgaccaaa aaagagatta gagaagtgct aggcattcct gaacggacat
      421 tagataaatt gctgaaggta ctgaaggcga atcaggaaat tttctttaag attaaaccag
      481 gaagaaatgg tggcattcaa cttgctagtg ttaaatcatt gttgctatcg atcattaaag
      541 taaaaaaaga agaaaaagaa agctatataa aggcgctgac aaattctttt gacttagagc
      601 atacattcat tcaagagact ttaaacaagc tagcagaacg ccctaaaacg gacacacaac
      661 tcgatttgtt tagctatgat acaggctgaa aataaaaccc gcactatgcc attacattta
      721 tatctatgat acgtgtttgt tttttctttg ctgtttagcg aatgattagc agaaatatac
      781 agagtaagat tttaattaat tattaggggg agaaggagag agtagcccga aaacttttag
      841 ttggcttgga ctgaacgaag tgagggaaag gctactaaaa cgtcgagggg cagtgagagc
      901 gaagcgaaca cttgattttt taattttcta tcttttatag gtcattagag tatacctatt
      961 tgtcctaata tgattttagc agtataattg acttggtgaa taggtcattt aagttgggca
     1021 taataggagg agtaaaatga aaaaatttat ttatcgagtt ttagaaaatg acgaagtggt
     1081 ggctattttt aatgagcaac aatatgcgca agattttatc gcttacgaaa agacaatttc
     1141 tgataagcaa tttgaaattg aaaaagtaga tattgctgat tggttattgc aaccgagaga
     1201 attttagagg ttggttgaaa atggctaaaa ttggttatgc acgtgtcagt agcaaagaac
     1261 agaacttaga tcggcaatta caagcgttac agggcgtttc taaggtcttt tcagacaaat
     1321 taagcggtca atcggtcgaa cgcccacaat tacaagctat gcttaactat attcgtgaag
     1381 gggatattgt tattgttact gaattagatc gattaggacg aaataataaa gaattaacag
     1441 aattgatgaa tcaaattcaa attaaggggg caaccctgga agtcttaaat ttaccctcaa
     1501 tgaatggtat tgaagatgaa aatttaaggc gtttgattaa tagccttgtc attgaattgt
     1561 acaagtatca agcagaatca gaacgaaaaa aaattaagga acgtcaggca caaggaatcg
     1621 aaattgctaa gaaaaaaggc aaattcaaag gtcgtcagca taaatttaaa gaaaatgatc
     1681 cacgtttaaa gcatgctttc gatttgtttt tgaatggttt atccgataaa gaagttgaag
     1741 aacaaactgg aatcaatcgc cgaacgttta gaaggtatcg agcaagatat aacgtgacag
     1801 tcgatcaaag aaaaaacaat gaaaagaggg atagttaatg agtacggtta ttttagctga
     1861 aaaaccaagc caggcattag cctacgcaag tgctttaaaa caaagcacca aaaaagacgg
     1921 ttattttgag atcaaagacc cactatttac agatgaaacg tttatcacct ttggttttgg
     1981 gcatttagtg gaattagcag aaccaggtca ttatgacgaa aagtggcaaa attggaaact
     2041 tgaatctttg ccgatttttc ctgatcgata cgattttgaa gttgcaaaag ataagggaaa
     2101 gcagtttaaa attgttgcag aacttctcaa aaaggcaaat acaattattg ttgcaacaga
     2161 tagcgacaga gaaggtgaaa atatcgcctg gtcgattatc cataaagcaa atgccttttc
     2221 aaaagataaa acatttaaaa gactatggat caatagctta gaaaaagatg taatccgaag
     2281 cggttttcaa aatttgcaac ctggaatgaa ttactatccc ttttatcaag aagcgcaaac
     2341 acgccaaatt gccgattggt tgatcggcat gaacgcaagc cctttgtata cgttaaattt
     2401 acaacagaag ggcgtacaag gtacattttc actaggacgt gttcaaacgc ccaccttata
     2461 ccttattttt cagcgccagg aagccataga gaattttaaa aaagaacctt ttttcgaggt
     2521 ggaagctagt ataaaagtaa accaagggtc gtttaagggc gttctaagcc ccacacagcg
     2581 ttttaaaacc caagaggagc ttttagcttt tgtttcttct aaacaagcta aaataggcaa
     2641 tcaagagggg ataattgctg atgttcaaac caaagagaag aaaacgaata gtccgagttt
     2701 gttttcttta agtagtttgc aatcaaaagt caatcagctt tataaagcga cagcgagcca
     2761 aactttaaaa gctatttctt ttttaataac ttaaaaataa acttaatgta acagcaagca
     2821 cagtcaaggt atacaccttt gacaaaaaat agcacattct ctatcgaaaa tttttgctta
     2881 ttttttaaat tattttggga aattttccca atcccttttt ctaactcaaa aaatataatc
     2941 actcaaaatt taaaagggcg cacttataca tcattttaaa aaattgatgt aacgtgctaa
     3001 gttcaaaaca aagggcgcac ttatacacga ttttcaatct tgtatatttc taacgaaaag
     3061 cgtgcgccaa aaaaccccct tcgtcaattt tgacaggggg ctttttgatg taaaaatttc
     3121 tatcgaaatt taaaaattcg cttcactcat gttataaaga cttaaaataa aataactctt
     3181 taaaatcttt tgctagttgt tcttcaatat tttttattcg gtgcatcttc caagtaaagt
     3241 ataacacact agacttattt actacgtttc ataagtcatt aatgcgtgtg ctctgcgagg
     3301 ctagtttttg tgcaagcaca aaaaatggac tgaataaatc agtccataag ttcaaaacca
     3361 aattcaaaat caaaaccaca agcaaccaaa aaatgtggtt gttatacgtt cataaatttt
     3421 atgatcactt acgtgtataa aattaaattc actttcaaaa tctaaaaact aaatccaatc
     3481 atctacccta tgaattatat cttgaaattc attcataaat agtgaagcat ggtaaccatc
     3541 acatacagaa tgatgaagtt gcagagcaac tggtatataa attttattat tctcactata
     3601 aaatttacct atcgtaataa taggcaataa aaagctgcta ttgttaccaa tatttaaatt
     3661 aaatgaacta aaatcaatcc aaggaatcat tgaaatcggt atggtgtttt caggtatcgg
     3721 ttttttagga aacatttctt ctttatcttt atattcaagc aagtcatttt tataattatt
     3781 ataaaaagaa atgaagtttt tatcagattc agtccaaatg ttagtaaatt tttcagtttg
     3841 cttattaaaa actgtataca aaggatttaa cttatcccaa taacctaatt tattctcact
     3901 attaattcct gttctaaaca ctttattttt atttacaact tccataattg cataaattaa
     3961 agagggataa atttcatatc ctttcttttt tatcatatct ttaaacaaag taatatcaat
     4021 ttctttagta atgctataag tagtttgctg attaaaatag tgttcaaaat attcttttct
     4081 atcccaattt tctaattcaa taatattaaa agtcatatat aacttcctcc taaattttaa
     4141 atttttatat ttaggaggaa taatcctctg attttttcat acgttatgtc acctcgtaaa
     4201 tattaattat actgaattag caatttttat caaataaaac ttattttact tccaaaacct
     4261 aaattcacgt tgccaaaaat caatctgctt ttgcaattgt ttttcgttcg cttttaaagt
     4321 cgatttcatt aattccgtta aatcaattgg agatatttct ctaatcaatt ttttaaattt
     4381 agtcttagta ttcttactta gctttcccca catactttct tcatgcaaca aagtataaac
     4441 catagcttgc tcattaattt tttctaaagt agcccacgca ggtttcaaga tgtgtaaatc
     4501 attaaaacaa tcattccagt aatcaaccat atctcttttt aattcaactt ctacacgcca
     4561 taaatgttca gacacaactt caacatctgc gttatcttta cgttcttgtt ttttattata
     4621 aattctaata aatctatcac tatcacggac accaaaatat tttgtttctg gcttgccatt
     4681 acgaccataa aaaacagttt tcttaactgc tttatcagtc attgcatagt aatcgctcaa
     4741 atcatcttca aaatcaaaag ctaagtctaa tcttgtaaaa ccgtcatctt ccatgtagtc
     4801 gataatattt tgttttaacc aaatcatttc ttcatgtgtg agtttattgg gattaaattc
     4861 aacacgcata ttacgtctat cccaagtatc tgcttttact ttgtcatatt cgatataaac
     4921 tttttcttga agtgccttag ctttaaactt tgtttgaagt atatcccaaa gtcgtatttg
     4981 tggctctaca ctcataaagt cagatagctt tttagcatta gttttgttca aatttccaac
     5041 gattgtcatg gcatcaaaac ttaatgcggg ttgagatttt cccaaagttt gaccacttaa
     5101 ccggctatta cttaaccggc tattagagac ggccggtttt tttagtgaga tttctgcagc
     5161 taatttttca tcaattttct tcatttttta tcgctcctaa aataattttt ggaacgaaaa
     5221 aaggacgagt ggaatcgcaa aataaatttc gcctgtatcc attcgtccat tttgttttgt
     5281 attcaaaatc aaaaattgat atactaatca tcgaatgaat aacaagtgtg gtttgttatt
     5341 ccgggcgaga acgttggtag cgttgctcgt ctttttttat gtcttttttt cgttaaaact
     5401 attttaaaac taaatatatc ttaaagcaaa taaattcaag gggctaaaag cgccccttaa
     5461 aaaccccttg cctctgaaaa gttttgtgtt tcctttccgt cggtttcaaa agctaattta
     5521 ctcaaaaaaa tagatcaagg gtaaatgcac tcactgcgtt cgcccttgag ctattttatt
     5581 tcgcaaattt taacgcattt gccgacgaaa agataaaaca cataaaaata tacgcagata
     5641 tatttaaaac gtcttagaac gcaaaatttt acgtttaaaa gctatgcaag gactgtatga
     5701 agcaaaatta ttgagttatc caagaacaga tacaccattt attacagaga acgaatttgc
     5761 ttatttaaaa gcgaattttg gcaaatatag cggtttttta ggacttgatc ttgaaatggt
     5821 tcaaacagag cctagaaagc gttatgtgga cggtagtaag gtacaggaac accacgccat
     5881 tatcccaaca aaacaagtac ctaccgaatc tgcattagcg aaaatggacg atttacaacg
     5941 aaaaatttat gctttagtcg ttaaaacgac cgttgccatg tttttacctg attacttgta
     6001 tgaagaaacc aagatacaaa cgaaagtagc tgatttgctg tttcaatcga tcggaaagac
     6061 accaaagcaa gaagggtgga aaattctttt caaacaacaa accaaagaag aaaaagagga
     6121 cgttcaaacg ttaccactcg ttatcattgg cgaacgtgcc gaagttggtg ttaagagtgt
     6181 tgaaaaagaa acgcaaccgc caaaagcttt tacagagggt acattattaa ctgctatgaa
     6241 aacggcgaat aaaacggttg atgatgaaga agcaatcaag attttacaag aagttgaggg
     6301 gattggaaca gaagcgacaa gagcaagtat tattgaagcg ttaaaacaaa aagaatatat
     6361 ccaagtgatt aagaataagc ttgttgtaac tgaaaaagga aaattattgt gccaggcagt
     6421 tgaaagtcag caccttttaa cgagtgctga aatgacggct aaatgggaaa cgtatttaaa
     6481 aaaaatcggt aaaagagaag gcaatcaaga gaactttatt acgaatatca aaaaattcat
     6541 tgttcattta ctggaagctg tacctaacga tatagaaaaa ctaaattttt ctgattacca
     6601 ggaacagaaa gaaaaagaag cagaaaaaag tattgtagga aaatgtccta agtgtggcaa
     6661 caatattgta ttaaaaaaat cgttttatgg ttgttcaaat tatcctgaat gtaagtttac
     6721 tttagctgaa cattttagaa agaaaaaact aaccaaaacg aatgtaaaag aattactgga
     6781 gggaaaagaa accctggtaa aaggaatcaa aaacaaagag aaaaagccct acaatgccgt
     6841 tgtaaaaatt ggggaaaagg gatatattga ttttatatct ttctcaaaat aaacataaaa
     6901 gccctttaaa gagggctttt atatattaat cacaaatcac ttatcacaaa tcacttatca
     6961 caaatcacaa gtgatttgtg attgttgatg ataaaataag aataagaaga aatagaaaga
     7021 agtgagtgat tgtgggaaat ttaggcgcac aaaaagaaaa acgaaatgat acaccaatca
     7081 gtgcaaaaaa agatataatg ggagataaga cggttcgtgt tcgtgctgac ttgcaccata
     7141 tcataaaaat cgaaacagca aagaatggcg gaaacgtaaa agaagttatg gaaataagac
     7201 ttagaagcaa acttaagagt gtgttgatag tgcattatct taaaattttg tataatagga
     7261 attgaagtta aattagatgc taaaaatttg taattaagaa ggagggattc gtcatgttgg
     7321 tattccaaat gcgtaatgta gataaaacat ctactgtttt gaaaca
//
LOCUS       DAZKKZ010000098         7225 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.101, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000098 DAZKKZ010000000
VERSION     DAZKKZ010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7225)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7225)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7225
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.101"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            1..483
                     /locus_tag="ACG8LA_002650"
                     /pseudo
     CDS             1..483
                     /locus_tag="ACG8LA_002650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002387932.1"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
     gene            648..863
                     /locus_tag="ACG8LA_002651"
                     /pseudo
     CDS             648..863
                     /locus_tag="ACG8LA_002651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397514.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            1001..1972
                     /locus_tag="ACG8LA_002652"
     CDS             1001..1972
                     /locus_tag="ACG8LA_002652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFQ0204910.1"
                     /translation="MKTTMKDVAALAGVGVGTVSRVINGVKVKEVTKEKVMAAISELN
                     YEPDEYARGMKTNSSNTIALILPTIWHPFFSEFAYYVEEALSQKNYKLFLCNANGSAE
                     KEKEYIQMVKQSKVDGIIGITYSDIDKYVSSNLPFVSIDRHFSEQVSYVTADNYLGGQ
                     IAAQELLTRNCKNLCYVGGVSPYPNETNNRKAGFYNICEENKIAVKVLDMPEPISNLE
                     EQLLAFFSDNPEIDSIFTINDFMALDVIKAQKKLGKEAPKDFQIIGFDGVKLSLQKDY
                     LLSTIVQPIEEMAKVSVETLMAMILNEEPPKRVVVPVFFHAGETTKE"
     gene            2111..3424
                     /locus_tag="ACG8LA_002653"
     CDS             2111..3424
                     /locus_tag="ACG8LA_002653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HFQ0204911.1"
                     /translation="MKKRMLAIAAILALTAGGLAGCGSKEKSSGSSDSGEIKIWVQFS
                     DETPEGKAWAEIVNNFNDEYEGEYKAVTEYIPRSGSGGGYEDKVNAAITTNTLPDVIT
                     LDGPNTAAYAHSGVIAPLDDYLKDADMDDVLDSIIQQGTYDGKMYAFGFSESSVGVYY
                     NKSLFKDAGITEDQLPTLEDPWTWTEFQAICQKLTDKYKTPAIDMQMASGDEMLTYAY
                     TPFVWSNGGDVVNADGTKAEDYFNGKKSVEALEFIQELVEKGYTTISPIEKGFETGKY
                     AMLLSGSWTMADLEENYQEIDYGILPYPVSDATGELVSPTGSWQLAMTEKTEKKDASA
                     AFIKFATSTESSRIMSLGNSVLPIRNSTVDLIKDEVSEGMQVLIKQNQISGHARPVVV
                     AYPQVSRAFQQAVQDISYFEENPDVQKVADSRAAEMQQAIDTSLK"
     gene            3467..4333
                     /locus_tag="ACG8LA_002654"
     CDS             3467..4333
                     /locus_tag="ACG8LA_002654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFQ0204912.1"
                     /translation="MKDNLIGYGFLAPALLLLTIFLIIPVIMVIYYAFTDYYLLTPDA
                     RQFIGLENFKRLFADPIFVKSIWNTAKFVVWIIPVQLGAALGMALIINKNRKGNIFFK
                     VAFFAPVVMSLVVISILWLYLLNPNEGLVNTLFAKIGIASQPFLTSPKQAMYTLVFVS
                     AWQGAGYQMLLFLGGMQNIPQDVYEAAEIDGFSKFQQFRYITMPLLKPTAIFILLTTL
                     ISAFKLIIQPMVMTQGGPMNSTMTMVYYIYQTGFTDRMVGYSSSIALIFTTMIGLITI
                     AQRKLVKEDDPA"
     gene            4330..5178
                     /locus_tag="ACG8LA_002655"
     CDS             4330..5178
                     /locus_tag="ACG8LA_002655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFQ0204913.1"
                     /translation="MTKKFGPLMIVEYCLLFLLAALFIFPMLWMVVSSMKPEADVYQN
                     LASFKAFLPSLNPANWFKTYQEVISRFSVGTYLLNSIFYGLTFACGSIIVNSLAGFAF
                     AKVNFSGKKIIFGALLALLIVPMETVLIPQFTIVNSLGLVNTRLAVILPAMASAFNIY
                     LFRNFFIAIPEEIIESAKLDGANIVKIFFHIMLPMSKPAIATVGVLSFISSWNDYIWP
                     LMVLTDSSKFSMQVAITTINTTQPVYINQVMAVLTIATIPLIIVYIVAQKYILQGLGG
                     SGTGIK"
     gene            5192..6664
                     /locus_tag="ACG8LA_002656"
     CDS             5192..6664
                     /locus_tag="ACG8LA_002656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HFQ0204914.1"
                     /translation="MLQKLLKANEFIEKNAQTVNQEYRNKFHLMAPIGWMNDPNGFVY
                     YQEEYHLFYQYYPYDSIWGPMHWGHAKSKDLIHWEHLPVALAPGESYDKEGCFSGSAI
                     EKDGKLYLIYTGHNVVEGQVRQVQCLAVSEDGIHFEKYAGNPIIAEDHLASVATTEDF
                     RDPKVFQRKEDYFTVVATKTADARGQIVMFHSKDLLTWEFYSVLLEGTPEQGIVWECP
                     DLFELDGKEVLILSPIQMTPQGNAYQNTNSTVAFIGTVDWQTGKFLVENFHEIDGGLD
                     FYAPQTCENEAGQRIMIAWMQMWQRKIPTNDLGHGWSGSMTLPRELRVADNQLLQRPV
                     SSIYQVIDPQERIEWAKTEENRFLLKDLVYDQHYLRLEINLKQATKLELHYAKGPDHT
                     LLLNYDVERECFTASREHMPYDLSGAEKEVLKKRSVTIPLENNCLTIEIFRDTSAIEL
                     FLNDRLTMSTTFYETEKGQDFLLLADSEVTFSLESGLINL"
     gene            6681..>7225
                     /locus_tag="ACG8LA_002657"
     CDS             6681..>7225
                     /locus_tag="ACG8LA_002657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HFQ0204915.1"
                     /translation="MIYGSIEAGGTKFVCAIGDEEMTIKERVSFPTTTPEETIPLVID
                     FFKQYQADLAGIGIGSFGPIDIHRDSATYGYITSTPKLAWQNFDFIGTMKKEFPIPIS
                     WTTDVNAAAYGEYVFGSGKGLSSVVYYTIGTGVGGGALQEGRFIEGFSHPEMGHMLVV
                     PHPKDDFAGSCPFHGNCLEGMA"
BASE COUNT         2243 a         1230 c         1557 g         2195 t
ORIGIN      
        1 gtaaaattta cttgtagttt tactgttatc atagcatttt taaaaataaa ttttaagtct
       61 acttataatt tactttggag gttttgaatg aatgaaatta agcgcaataa aaattctttt
      121 ggtgtttatt taggagagcc tagctcggaa cagttaaata aaggtgaagc tcgtcatgct
      181 ctatgtcgaa atatatttta tggtagaaaa ggcaaacttt atcaaactta ttacgacggt
      241 atggaggaac agctcaacgc attaggatta gtaactaatg ctatcatata ttggaattca
      301 ctatatttag aaaaagtctt tgaacaaatt aaaacggaag ggttcgactg ttccgaagaa
      361 gtgttacgca agcaatctcc attaattagt gatcacatta attttgttgg caaatatagt
      421 ttccgctatg aaaaagaatt atcgaatgga atactacgtc cgttaaatat agagaattat
      481 tgagaatgtt cgtcttttgg ttcctaccgt gcattttcgc acggatgttc cagatactat
      541 ttttgaatgt ataaaattga aaacacaaga atactaataa atcaacgatt cttgtgtttt
      601 taatttttca ctaccgtgca ttttcgtttc tatgttccat gtaccccaat cttgaaaaat
      661 taattaaaga cttagataaa gccattgacg acttagtcgt ggtgctaccg gagtatcaat
      721 gtttaaccag tatcccaggt attggtcctg tttaggctgc tggaatactc gctgaaattg
      781 gtccaattga acgtttttct gatgaaataa aattgacaaa gtatgccggc ctatattggc
      841 gacagagtca atccggtaaa tctgaatacg aaaatttttt tacgaaaagc ttcacgtcta
      901 atatctattt taaaataaaa atattcctgc taatttggaa tcgtttcctt cttttggtat
      961 aataatacct gaaattcttt tgagaggagt tgttcgtgaa gtgaaaacta ctatgaagga
     1021 tgttgctgcg ttagcaggag ttggtgtggg tacggtatct agagtaataa atggagtaaa
     1081 ggtgaaagag gttaccaaag aaaaagtaat ggctgcaatt agtgagctta attatgagcc
     1141 tgatgaatat gccagaggta tgaaaacgaa tagtagcaat acaatagctc ttattttacc
     1201 tacgatttgg catcccttct tttccgagtt tgcctactat gtagaggaag ctctcagcca
     1261 aaaaaattat aagctttttt tgtgtaatgc gaacggcagt gcggaaaaag aaaaagaata
     1321 tatccaaatg gtcaagcaga gtaaagtaga cggaattata ggtattacct attcagacat
     1381 tgataaatat gtatcatcaa atttaccatt tgtcagtata gaccgccatt tttcggaaca
     1441 ggtttcttat gtaacggcag ataattattt aggtgggcaa attgccgctc aagaactact
     1501 tactcgtaac tgtaaaaact tgtgctatgt tgggggtgtt tcaccttacc ctaacgaaac
     1561 aaacaatcgt aaagctggtt tttacaatat ttgtgaggaa aataaaatag ctgtgaaggt
     1621 attggatatg cctgaaccaa ttagcaattt agaggaacaa ttgctcgctt ttttttcgga
     1681 taatcctgaa attgatagca tttttaccat caatgatttc atggctttgg atgtgataaa
     1741 agcccaaaaa aaactaggga aggaagcacc taaggatttt caaattattg gttttgatgg
     1801 agtcaagcta tcgttgcaaa aagactattt actatcaacg attgtacagc cgatagagga
     1861 aatggccaag gtttcagtag aaacactcat ggcgatgatt ttaaatgaag aaccgcctaa
     1921 gcgtgtggta gtaccggttt tctttcacgc tggagagacg actaaagagt aaaaaaccgg
     1981 tttataacga tttttttgag ataggttgac agaaagtgat ttcaatgata tcttaaaacc
     2041 aattaattgg aaacgttacc aattaattga aaaataaaac ggaaacgttt caaaaatagg
     2101 aggaacatcg atgaaaaaga gaatgttagc aattgcagca attttagcat taacagctgg
     2161 aggacttgca ggatgtggca gtaaggagaa aagttcaggt agcagtgatt caggagaaat
     2221 taagatttgg gttcagtttt ctgatgaaac gcctgaagga aaagcttggg cagagattgt
     2281 gaacaatttt aatgatgaat acgagggtga atataaagct gttactgagt atattcctcg
     2341 tagcggaagc ggcggtggat atgaggataa agtaaatgct gcaattacaa ccaataccct
     2401 tcctgatgtt attacgttag atggaccgaa tactgcagct tatgctcatt caggagtcat
     2461 tgctccatta gatgattatt tgaaagatgc ggacatggat gatgtattag acagcattat
     2521 tcagcaagga acctacgatg gcaaaatgta tgcgtttggt ttctcagagt ccagtgtggg
     2581 tgtctattac aataagtcgt tgttcaaaga tgctggaatt acagaagatc aattgccgac
     2641 gttagaagat ccttggactt ggacggaatt tcaagcaatt tgccaaaagc tgactgataa
     2701 atacaaaacg cctgcaattg atatgcaaat ggcgtcggga gacgaaatgc tgacctacgc
     2761 atatacacca tttgtatggt cgaatggcgg cgatgtcgtt aatgctgatg gaaccaaagc
     2821 cgaagactat tttaacggta aaaaatccgt tgaagcgttg gaatttattc aagaattggt
     2881 tgaaaaaggt tacaccacaa tcagtcctat tgaaaaagga tttgaaactg gcaaatatgc
     2941 catgctgctg agcggttctt ggacaatggc agatttagag gaaaactatc aagagattga
     3001 ttatggtatt ttgccttacc ccgtttcaga tgcaactggg gagttagttt caccaaccgg
     3061 aagctggcag ttagcaatga ctgagaaaac agagaaaaag gatgcttctg cggcctttat
     3121 taagtttgca accagtacag aatctagtcg tattatgagt ttagggaaca gtgttctacc
     3181 tatcagaaat tcaacagttg atttaattaa agatgaagtg tcggaaggaa tgcaggtatt
     3241 aattaagcaa aaccaaattt ctggacatgc ccgcccagtg gttgtagctt atccgcaagt
     3301 atctagagca ttccaacaag cagttcaaga tattagctac ttcgaggaaa acccagatgt
     3361 acaaaaagta gcagatagtc gcgctgctga aatgcaacag gcaattgata cttcactaaa
     3421 atagaagttt ctaaaggggg ccaatcaagt gttaaaaaaa ccgacaatga aagacaattt
     3481 gataggttac ggctttctag cgccagcttt gctgctgctg acgatttttc tgatcatacc
     3541 cgtaatcatg gtaatttatt atgcctttac tgattattat ttgttaacgc cagatgctag
     3601 acaatttatc ggcttagaaa attttaagcg actgttcgct gatccaattt ttgtaaaaag
     3661 tatttggaac acggctaaat ttgttgtttg gattattccg gtccaattag gggcagcttt
     3721 aggaatggca cttattatca acaaaaatcg taaaggaaat atctttttta aagtagcctt
     3781 ttttgcgcca gtcgtgatgt ccttagtcgt tatttcgatt ttatggttgt acttgttaaa
     3841 tcctaatgaa ggtctggtta atacgctatt tgcaaagatt ggaattgctt cgcagccttt
     3901 tttgactagt cccaaacaag caatgtatac gcttgttttc gtatcggcat ggcaaggtgc
     3961 aggatatcag atgctgctgt ttttaggggg aatgcaaaat attccgcaag acgtttatga
     4021 ggcagccgaa attgatggtt tttctaagtt tcagcaattt cgctatatca ccatgccatt
     4081 attaaagccc acggcgattt ttattttact taccacattg atttcggcct ttaaactaat
     4141 cattcagcca atggtaatga ctcaaggtgg accaatgaat tctactatga caatggttta
     4201 ttacatttac caaactggat ttacagaccg tatggtaggc tactccagct ccattgcgtt
     4261 aatctttacc actatgattg gtttaattac aattgctcaa agaaaattgg taaaggagga
     4321 tgatccagca tgaccaagaa atttggaccg ctaatgatcg tagaatattg tttgctgttc
     4381 cttttagcgg cattattcat tttcccaatg ctgtggatgg tagtttcctc tatgaagcct
     4441 gaagcagatg tctatcaaaa tttagcttcc ttcaaagctt ttttacctag tttgaatcca
     4501 gctaattggt ttaaaactta tcaagaagtt atttcccggt tcagtgtggg aacttattta
     4561 ttaaacagta ttttttatgg tttaaccttt gcctgtgggt caatcattgt aaactctttg
     4621 gccggttttg cctttgcgaa ggttaatttt tcaggcaaga aaattatctt tggagctttg
     4681 ttagctctgc tgattgtccc gatggagacg gttttaattc cgcaatttac catcgttaat
     4741 tcactaggct tagtgaatac tcgcttggca gtgattttac cagcgatggc cagcgcgttt
     4801 aatatctatt tgtttagaaa tttctttatc gcgattccag aagaaatcat tgaatcagcg
     4861 aaattagatg gtgcaaatat tgttaaaatt ttctttcaca tcatgctgcc aatgtctaaa
     4921 ccagccatag ccacagtagg tgtcttatcc tttatctcca gctggaatga ttatatttgg
     4981 ccgttaatgg tcttaactga cagcagcaaa ttttcaatgc aagtggcaat tactacgatc
     5041 aatactacac agccagttta tatcaatcaa gtgatggctg ttttaaccat tgcaacgatt
     5101 ccactgatta ttgtttatat cgttgcacaa aaatatattc tgcagggact tggcggttct
     5161 ggaacgggta taaaatagga gtgaatagtg aatgttgcaa aaacttttaa aggccaatga
     5221 gtttattgag aaaaatgctc aaacagtcaa tcaagaatac cggaataaat ttcatttgat
     5281 ggctccgatt ggctggatga atgatccaaa tggttttgtt tattatcaag aggagtatca
     5341 cttgttttat caatattatc cttacgacag catctgggga ccaatgcatt ggggccatgc
     5401 taaaagcaag gatctaattc actgggagca tttgccagta gcactggcac caggtgaaag
     5461 ctatgacaag gaaggctgtt tttccggcag tgccatagaa aaggatggca agctgtattt
     5521 gatttataca ggacacaatg ttgtggaagg gcaagttcga caagttcagt gtttggcagt
     5581 ttcagaagat ggcattcact ttgaaaaata tgccggaaat ccaatcatcg cagaagatca
     5641 cttagcttct gttgcaacga ccgaagattt ccgcgatccc aaagtgtttc agcgaaaaga
     5701 agactatttt actgtagtcg ctactaaaac tgcagatgct cgtggacaaa ttgtgatgtt
     5761 ccattccaaa gatttactaa cttgggagtt ttattccgta ttgctggagg gaactccaga
     5821 acaaggcatt gtatgggaat gcccagactt gtttgaacta gatggcaaag aagtcttgat
     5881 tctttctcct attcaaatga ctccacaagg caatgcttac caaaatacga actcaactgt
     5941 tgctttcatc ggtactgtcg attggcaaac aggcaaattt ctagtagaga attttcatga
     6001 aatcgatggc ggtttagatt tttatgcacc ccagacctgt gaaaacgaag caggccaaag
     6061 aataatgatt gcttggatgc aaatgtggca gcgtaaaata cctacgaatg atctgggcca
     6121 tggttggtca ggttccatga ccttgcctag agagctgagg gtggctgata atcaattgtt
     6181 gcaacggcca gtttcatcaa tttatcaagt aattgatccg caggaaagga ttgaatgggc
     6241 gaagactgaa gagaatcgct tcttactgaa ggacttagta tatgaccagc actatttacg
     6301 cttggaaatc aatttaaaac aggcaacgaa actagaactt cactatgcga agggacccga
     6361 ccatacatta ctgcttaact atgatgttga acgggagtgc tttactgctt ccagggaaca
     6421 catgccgtat gatttatcag gagctgaaaa ggaagtgttg aaaaagcgca gtgtgacgat
     6481 tcctttggaa aataattgtc taaccatcga aattttccgt gatacttcag ctattgagct
     6541 ttttctaaat gatcgtctga ctatgagtac aactttttat gagacagaaa aaggacagga
     6601 ttttcttttg ctggcagaca gtgaagtaac cttttcattg gaaagcggct taattaatct
     6661 atagaaggga gagctcagtg atgatttatg gttcaatcga agcaggcggc acaaaatttg
     6721 tgtgtgccat tggcgatgaa gaaatgacga tcaaggaaag agtgagcttt ccgacaacga
     6781 cacctgagga aacaatacct ttagtcattg acttcttcaa acaataccaa gcagatttag
     6841 cagggattgg gattggctca tttgggccta tcgatatcca tcgcgattcc gccacttatg
     6901 ggtacattac ctcgaccccg aaattggcat ggcaaaattt tgatttcatc ggtaccatga
     6961 aaaaagaatt tccgatcccg atttcttgga caacagatgt caatgcggct gcctatggtg
     7021 agtatgtctt cggcagtggc aaaggattga gcagtgtcgt ttactatacg atcggtacgg
     7081 gtgttggcgg cggtgcctta caagaagggc gctttatcga agggtttagt catccagaaa
     7141 tggggcatat gctcgtcgtc cctcatccaa aagatgactt tgctggcagc tgtccatttc
     7201 atggcaactg tttagaaggg atggc
//
LOCUS       DAZKKZ010000099         7011 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.102, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000099 DAZKKZ010000000
VERSION     DAZKKZ010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7011)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7011)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7011
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.102"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            323..919
                     /locus_tag="ACG8LA_002658"
     CDS             323..919
                     /locus_tag="ACG8LA_002658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HFQ0204916.1"
                     /translation="MTTFTDTLKNRRSIYHLGRNVSLSNEELTTLIKEAIKESPTAFN
                     AQSTRAVILFGDAHEKLWEITEEALRPLTPAEAFPNTQNKLAGFKNGYGTVLFFKDTD
                     VVKGLQEQFELYADNFPDWSEQSNGIATANTWVALVDKGLGANLQHYNPVIDEAVAKE
                     WNIPSNWKLRSQLVFGSPETPAEEKEYMNDADRFRVFG"
     gene            complement(977..1459)
                     /locus_tag="ACG8LA_002659"
     CDS             complement(977..1459)
                     /locus_tag="ACG8LA_002659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204917.1"
                     /translation="MVTFFTVLLFLFVVVMFLFLWLVRKEIIYRTVRNRWVYLVIPFL
                     VSLVIWYTLISHPTADELAKGILSAMIFISFLLDSRGITEEGLVLNSFDKKGVPFSEI
                     NKIVLYQPKGSKIVKMNFFRNGWRGPMLKFSASLEELVPFLSQRLNDEAEIDIMIDPE
                     "
     gene            complement(1565..1762)
                     /locus_tag="ACG8LA_002660"
     CDS             complement(1565..1762)
                     /locus_tag="ACG8LA_002660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204918.1"
                     /translation="MTEEMINLGEQYACKPIGFTKTVIGEVVSKMTNCAVVKVAQCAA
                     EDQELLDEKASMVVAKYDTFE"
     gene            2057..2815
                     /locus_tag="ACG8LA_002661"
     CDS             2057..2815
                     /locus_tag="ACG8LA_002661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C39 family peptidase"
                     /protein_id="HFQ0204919.1"
                     /translation="MKKKTFKKLLFLGGTAALLLSGTSYYLHIHSPEHTMNTAQKSST
                     QKTKKTKEKAEVLLDVPLESQFDSPSLENGCEVTSLSMLLSFYGYETTKNQLAEQLDY
                     VPVFNADGTHGDPNEGFVGDISGGDWAMVVYVPPVASLAQQIVQTDYHTFPKTDAQLD
                     DIKKALSKGNPVWTSVTINFEVPDETDFMTWTTNNGEVRVTPLVHACVVTGYDKENIY
                     VNDPYGVKNRAVPINDFSAIFTAMGGQMLTLEKS"
     gene            2875..3303
                     /locus_tag="ACG8LA_002662"
     CDS             2875..3303
                     /locus_tag="ACG8LA_002662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204920.1"
                     /translation="MEKFTHKKMDPNEIPIIFVRDCKGNVQGKVSINEWNERRRPATL
                     NELEIKLYRQSLVYYTDQEYEKATDLLKFLIARTEYTRFEYIERLANIYHIMNEPVKE
                     YQLLDTVLSVAELIALPAGLEKKLVRRLLRVKQQLSDQEK"
     gene            3349..3421
                     /locus_tag="ACG8LA_002663"
     tRNA            3349..3421
                     /locus_tag="ACG8LA_002663"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3382..3384,aa:Gln,seq:ctg)
     gene            complement(3571..3942)
                     /locus_tag="ACG8LA_002664"
     CDS             complement(3571..3942)
                     /locus_tag="ACG8LA_002664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HFQ0204921.1"
                     /translation="MKVIKYLIGLAAISGILLFGLKYYTEGSYGEIPGILDQLNPLVE
                     KGEVYVKTQKPEEVNEYGTARYVQKAADANGKERTVEFNGLSVLKENHYLKISNKGAH
                     IETYEEVPREKVPEKALAIIG"
     gene            4157..4342
                     /locus_tag="ACG8LA_002665"
     CDS             4157..4342
                     /locus_tag="ACG8LA_002665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204922.1"
                     /translation="MNQEELFQKVKEMIKNGNFDGAKRFIEEHKEQLGPYKEKAQNLL
                     KDVNIDSVKNKFKNLFK"
     gene            complement(4425..4613)
                     /locus_tag="ACG8LA_002666"
     CDS             complement(4425..4613)
                     /locus_tag="ACG8LA_002666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204923.1"
                     /translation="MNPYEQLIQDLIDGKIEKIDVKREELMAFREAWLKLENRKYVVG
                     KASLNGNVTYHYDPTRLF"
     gene            complement(4637..4900)
                     /locus_tag="ACG8LA_002667"
     CDS             complement(4637..4900)
                     /locus_tag="ACG8LA_002667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204924.1"
                     /translation="MDHVVLEIDLHLINNIRVIYYVVSNSVEQRVLTNKINGILAKKD
                     VHRFNNGEGSYYSIPVEKIIYTTVKVREDLDTKKAYEPIFTTY"
     gene            5058..5315
                     /locus_tag="ACG8LA_002668"
     CDS             5058..5315
                     /locus_tag="ACG8LA_002668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose uptake protein"
                     /protein_id="HFQ0204925.1"
                     /translation="MIAIGQFVFYIPFFIMISILFYYIKWTKKKFSVLLASLPAVYFT
                     YQIFSFRHWETTSVLITHIIELTLSVIFLIIWIYFLYKNQN"
     gene            complement(5386..5577)
                     /locus_tag="ACG8LA_002669"
     CDS             complement(5386..5577)
                     /locus_tag="ACG8LA_002669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204926.1"
                     /translation="MEAGKVLQEVKALCADKKYEEAKSLIEKNKENLEEKYPIAQEFI
                     ELKQGTILHRFKHFFGITE"
     gene            complement(5718..6038)
                     /locus_tag="ACG8LA_002670"
     CDS             complement(5718..6038)
                     /locus_tag="ACG8LA_002670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204927.1"
                     /translation="MVRPQEVRAPKEKIEILAIIEDGTQTKKGYSIALVKWKGKKGVA
                     LRWDGDNQQDKGFPVTANGYHPAWFVLPDKFMELYSYDYARAAASIKALDKLTEEQNE
                     MEEK"
     gene            complement(6061..6495)
                     /locus_tag="ACG8LA_002671"
     CDS             complement(6061..6495)
                     /locus_tag="ACG8LA_002671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HFQ0204928.1"
                     /translation="MSKRYQNIMVAVDGSRQSIKAFAEALDLAKDNEAHLFIVSIINK
                     VELTHSAYAFSKIYADEKQRTEVAMLKKINDAKEYGIAEIHAIVETGDPRNLIANVIP
                     GQENIDLIVMGATGKGAIQQALVGSTASYVVSHAPCSVLVVK"
     gene            6830..>7011
                     /locus_tag="ACG8LA_002672"
     CDS             6830..>7011
                     /locus_tag="ACG8LA_002672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HFQ0204929.1"
                     /translation="MTSLKTLLFGTTLAAGAAFFMGTTAHADEAYTVQSGDTLSTISQ
                     KYVGDNSLINAIAESNS"
BASE COUNT         2205 a         1363 c         1069 g         2374 t
ORIGIN      
        1 aaaaaactta tttaagaaat ataaactaat tttctataaa agcaagtaat ttttaatggc
       61 aatatcataa aaaaaagaag atagagattt aataattata tatcagctgt ttttttcaaa
      121 taagcaaaaa ttcctaaaac acaacaatga aagcgataac taagaaaatc cttacataac
      181 gatttttctt attaaaattg ttttttgaac ttcgcttatt ttttgtgagc atatctgttt
      241 acttactttt tgtaaggtgc tatacttcat ttcgtaatca attaaaaaaa tgcaaaacgc
      301 aaatcaaagg agaaatttta ttatgacaac ttttactgac actttgaaaa accgccgttc
      361 aatctatcat ctaggacgta atgtttcact ttctaatgaa gaattaacaa ctttgatcaa
      421 agaagcaatt aaagaaagcc caactgcttt caatgctcaa tcaacacgcg cagttatcct
      481 tttcggagat gcacatgaaa aactttggga aatcactgaa gaagcacttc gcccattgac
      541 tccagcagaa gctttcccaa atacacaaaa caaattagct ggtttcaaaa atggttatgg
      601 tacagtatta ttcttcaaag atactgacgt ggtaaaaggt ctacaagaac aatttgaatt
      661 atatgcagac aacttcccag attggtcaga acaatcaaac ggaatcgcaa cagctaatac
      721 ttgggtagca ttagttgata aaggattggg cgcaaacttg caacattaca acccagttat
      781 tgacgaagca gttgcaaaag aatggaatat cccttcaaac tggaaactac gttcgcaatt
      841 agtattcggt tcaccagaaa caccggctga ggaaaaagaa tacatgaacg atgccgatcg
      901 cttccgcgta tttggataat tttatttgaa ataaaaaaca gaggttgtga caaacatctt
      961 gtcgcaacct ctgtttttat tctggatcaa tcataatatc aatctctgcc tcatcgttta
     1021 agcgttggga caaaaatgga actaattctt ctaatgatgc agaaaatttc agcatcggtc
     1081 ctcgccatcc gtttcggaaa aaattcattt ttacgatttt agaacctttt ggctgatata
     1141 atacaatttt attgatctca gaaaaaggaa cacctttttt gtcaaagcta ttcaaaacaa
     1201 gtccttcttc tgtgattcct ctactgtcca acaaaaaact aataaaaatc attgctgaca
     1261 agatcccttt tgccaattca tctgctgtag gatgactgat gagtgtatac caaatgacta
     1321 gtgacactaa gaagggtatc accaagtaga cccatcgatt tcgcacagtc cgataaataa
     1381 tttcttttcg aaccagccaa agaaataaaa acatcacaac aacgaataaa aacaatagaa
     1441 ccgtaaagaa tgttaccatg acaactcgcc tcgctttttc ttctccagaa aataggaaaa
     1501 gaatactgat ttaccttctc aaagaaattg gacttgcagc acgccgcacg tccaattgtt
     1561 ttctttattc aaatgtatca tattttgcaa caaccatgct tgctttttca tctaataatt
     1621 cttggtcctc tgcagcacat tgggcaactt tgaccacggc gcagtttgtc atttttgata
     1681 caacttcacc aatgaccgtt tttgtaaaac caattggttt gcatgcatat tgttctccta
     1741 aattaatcat ttcttccgtc atcaaaatcc tcctaaactg ctggaacttt tctccacatt
     1801 accactgcta tttctttgga gatttaactc attgattttt atttacagtt aaaaatcaac
     1861 cttacaggca ttatagcgta ctgttttcgt tttcacaatt aaaacagctg ttgtatttag
     1921 aagaattttt ttcaaaaaat taaaacatat tccttaaaaa ctaattattt cctacatatt
     1981 aaaatataat acttccattt ccaataaaaa tacatttata ataggaaaga taaacagctg
     2041 aaaagggaga tttcaaatga agaaaaaaac gttcaaaaaa ctattgtttc tagggggcac
     2101 agctgctctt ttattaagcg gtacaagtta ttacctacat atccattctc cagaacatac
     2161 aatgaacact gcacaaaaaa gttcaacaca aaaaacgaaa aagacaaaag agaaagcaga
     2221 agttttacta gatgttccat tagagagcca gtttgattct ccttctttag aaaatggctg
     2281 tgaagtcact tcgctttcta tgcttttatc tttttatggt tatgaaacaa ctaaaaacca
     2341 gttagctgag caattggatt acgtccctgt tttcaatgca gatgggactc atggcgatcc
     2401 taatgaagga tttgttggtg atatcagtgg cggagactgg gctatggtcg tctatgttcc
     2461 cccagttgcc tcccttgctc agcaaatcgt ccaaacggat tatcacactt ttccaaaaac
     2521 cgatgctcaa ctcgatgata tcaaaaaagc actatctaaa ggaaatcctg tctggacttc
     2581 tgtgactatc aattttgaag tcccagatga aactgatttt atgacttgga ccacaaataa
     2641 tggagaagta agagtcactc ctcttgttca tgcttgtgta gtcactggat atgacaaaga
     2701 aaatatttat gtcaacgatc cctatggtgt aaaaaatcga gcagtaccga tcaacgattt
     2761 ttcggcgatt ttcactgcaa tgggtggaca gatgctaact ttggagaaaa gctagtaatt
     2821 caaacaaaaa tcccttatac tcaagatacc aaacctttga agggagcgta gataatggaa
     2881 aaattcacac ataaaaaaat ggatccaaat gaaattccga ttatttttgt ccgtgactgc
     2941 aagggaaatg ttcaaggtaa agtctctatt aatgagtgga acgagcgtcg cagacctgct
     3001 accctcaatg aactggaaat caaattgtat cgtcaatctc ttgtttatta cacagatcaa
     3061 gagtacgaga aagccaccga tttattgaaa tttctaattg ctcgaacaga gtatactcgc
     3121 tttgaatata ttgaacgttt agcaaacatc tatcatatta tgaatgaacc tgtcaaagaa
     3181 tatcagttat tggacaccgt cttgtcagta gcagaactga ttgcccttcc tgctggatta
     3241 gaaaagaaac tagtacgccg ccttttacga gtaaagcaac aactatccga tcaagaaaaa
     3301 taacttgcgt ttttttagga aagtgctatg attattttgt tgaataaatg ggatgtagcc
     3361 aaactggtaa ggcacttgac tctgaatcaa gcaattgtag gttcgaaccc tgccatccca
     3421 atttgatgtg cttgctgaaa aaatgaaccc cctgtaaaag aacaatcttt ttgcaggggg
     3481 attattgtat tatttttact acttgtattt agtttacata attaaattat gaataataaa
     3541 atcgggcgta ttcttaatac aaaaactgat ttacccaata attgctaatg ctttctccgg
     3601 aactttttct ctaggaactt cctcatacgt ttctatgtgt gctcctttat tgctaatttt
     3661 caaataatga ttttctttta acacagaaag accattaaat tcaaccgttc gttctttccc
     3721 attggcatca gcagctttct gcacatacct tgctgtacca tattcattta cttcctctgg
     3781 tttttgtgtc tttacataga cctctccttt ttcaactaat ggatttagct gatcaagtat
     3841 accagggatt tctccataac ttccttcagt ataatatttc agtccaaata gcaaaatacc
     3901 actaatcgcc gccagtccaa tcaaatattt aatcactttc atctttctac ctccttgtta
     3961 tatattcagt atatgggtca gttaaagaaa ttccatccgt cccaagttgg agatttttct
     4021 cctactttag aagcgagaat cgagtgtttt tttagtaaaa atgatcgtta tttgatatta
     4081 ttgacgtgtg gataaatcag tttttctcgt tttgtccatg taaaaaatca tgttgatagc
     4141 aaaggatgtg ttcaaaatga atcaagaaga attatttcaa aaagtcaagg aaatgattaa
     4201 gaacggcaat ttcgatggcg caaaacgatt tatcgaagaa cataaagaac aattaggacc
     4261 ttataaagag aaagcccaaa atcttttaaa agatgtaaat atcgacagtg tcaaaaacaa
     4321 atttaaaaat ctattcaaat aagtaaaact ttcacttttg taaaatcaaa ggaggacaat
     4381 gctgctgcat cgtcctcctt tggttctttt ctgaatactt catactaaaa taaacgtgtc
     4441 ggatcgtaat gataagtcac attgccgttc agtgaggctt ttcccaccac atatttacga
     4501 ttctccaact tcagccacgc ttctcgaaaa gccattaatt cttctctttt tacatcaatc
     4561 ttttcgattt ttccatcgat caaatcttga ataagttgtt catatggatt catttttttc
     4621 ctccatctgc tgtcaatcaa taagttgtaa aaataggttc atatgctttt ttggtatcta
     4681 gatcttctct gactttgact gtcgtataaa taattttttc tactgggata ctataataac
     4741 ttccttcacc attattgaat cggtgaacgt ctttctttgc taaaatacca tttattttat
     4801 tcgtcagtac acgttgttcg acactgttac ttacaacata gtaaatcacc cgaatattat
     4861 tgatcaaatg caaatcgatt tctaacacta catgatccat gaaaatccca ctccttcttt
     4921 cactttgatt atagcaagtt tctcctctaa tttcaaaatc gatacagatt ttaccggata
     4981 aatccacaaa actgcttgcg ccatttcgca caaagtgtta ttttgtatca tggactttat
     5041 ttatcggagg caatagtatg atcgcgatcg gtcaatttgt tttttatatt ccttttttta
     5101 ttatgataag cattcttttc tattacataa aatggacaaa aaagaagttt tcagttttac
     5161 tggcctcttt acctgctgta tattttactt atcaaatttt ttcttttagg cattgggaaa
     5221 caacgtctgt attaataaca cacatcatcg aattgacgct ttcagtaatt tttcttatta
     5281 tttggatcta ttttttatat aagaatcaga attgaatccc tcgcatgttt aaaaagaaaa
     5341 cgattaaaga tgcagcaaat ttctgccgat ctttaatcgt tttttctatt ctgttatacc
     5401 aaaaaaatgt ttgaatcggt gaaggatcgt tccttgtttt aattctataa attcttgtgc
     5461 gatcgggtac ttttcttcca aattttcttt gttcttttcg atcaggcttt tcgcttcttc
     5521 atatttttta tctgcacata gtgcttttac ttcctgtaat acttttcctg cttccatttg
     5581 cctcaccctc ttgccatttt attgctttaa gttttattta agttatacgc attattctag
     5641 tttcatccca aataaccttt tttcattttt actcctcgaa ctaatcagtt ttctaaaggc
     5701 tgattggttc gtctttttta tttttcctcc atttcattct gctcttctgt taatttatct
     5761 aatgctttga ttgatgctgc ggctcttgca taatcatagc tgtataattc cataaattta
     5821 tcaggcagaa caaaccacgc tggatgataa ccgttagctg tgacagggaa tcctttatct
     5881 tgttggttat ctccatccca tctcagagca acaccttttt ttcctttcca ctttactaaa
     5941 gcgatcgagt atcccttctt tgtttgtgtg ccgtcttcaa taattgctaa aatttctatt
     6001 ttttcttttg gcgcacggac ttcttgagga cgaaccattt tctattcctc ccttatctca
     6061 ttacttcacg accaacacac tgcaaggggc atgtgatacg acataagaag cggtcgatcc
     6121 aactaatgct tgttgtatag caccttttcc tgtcgctccc ataacgatca aatcaatatt
     6181 ttcttgtcca gggatgacat tggcaatcaa atttcttgga tctccagttt caactattgc
     6241 gtggatctca gcaatgccgt actctttggc atcattgatt tttttcagca tggctacttc
     6301 tgttctttgt ttttcatctg catagatttt tgaaaaggca taggcactat gggtcagctc
     6361 aactttgttg atgattgaca cgataaataa gtgggcttca ttgtcctttg ctaagtcaag
     6421 ggcttcagcg aacgctttga tcgattgtct tgatccgtca actgctacca tgatgttctg
     6481 gtatctttta ctcattggaa ccgcctcctt tttcttttat tgtaacatct caagcaaaaa
     6541 tacaaaaaat atacgcaata tgtaaataaa atgatgaaca aaagcaattt ctttcaagtt
     6601 atttatacat ttcttttctc atcagaacac ctgttctaat cccattattt ctgcattatg
     6661 tgaaattcct catcattttt cacatcgagc gaacatcatt ctgttacaaa aaacgtggat
     6721 ttgtcataaa ttgtcatgct tcttttacct atgaaatatt ttcacgtgtt aaagtattcc
     6781 tcgttgaaca caacaaataa aactttttaa cgaataaagg agatttttca tgacatcact
     6841 taaaacttta ctttttggaa caactttggc tgccggcgct gcattcttca tgggaacgac
     6901 tgctcatgcg gacgaagctt ataccgttca atcaggtgat actctatcaa cgatttctca
     6961 aaaatacgtt ggtgataact ccttgatcaa tgccattgca gaatcaaatt c
//
LOCUS       DAZKKZ010000100         6868 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.103, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000100 DAZKKZ010000000
VERSION     DAZKKZ010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6868)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6868)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6868
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.103"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..226
                     /locus_tag="ACG8LA_002673"
     CDS             <1..226
                     /locus_tag="ACG8LA_002673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007208413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0204930.1"
                     /translation="KTTEFDILHALMSTPNKVFSRSDLIEKVKGIEFDGLDRSIDSHI
                     KNLRHKIENDAKSPMYILTVHGTGYRFGGH"
     gene            226..1619
                     /locus_tag="ACG8LA_002674"
                     /pseudo
     CDS             226..1619
                     /locus_tag="ACG8LA_002674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294791.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
     gene            1634..1840
                     /locus_tag="ACG8LA_002675"
     CDS             1634..1840
                     /locus_tag="ACG8LA_002675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204931.1"
                     /translation="MFQKQIKIAKLVCECWAKKIFFQLISIDSVEKVHLDILSNSVVI
                     FSKKDLSIATIKKEVFGLQIYEMT"
     gene            1861..2457
                     /locus_tag="ACG8LA_002676"
     CDS             1861..2457
                     /locus_tag="ACG8LA_002676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdhK family protein"
                     /protein_id="HFQ0204932.1"
                     /translation="MKTVKKMTKLVFASLGIIVFLGACSNQSESNNSNSTNEESTSTA
                     SSEMNSMEGMNHEGMVPSSMKDAANPKFPVGSNVILLGDHMEGMKGANAQVVGAFDTT
                     MYEVSYEPKTGGPMVNNHRWVVQEELKDTETVANEGDTVILNADHMDGMMGAEAKVDK
                     SITGTVYVVNYTPTDGQEEVKNHMWVTEDEMEYDENNE"
     gene            3409..4008
                     /locus_tag="ACG8LA_002677"
     CDS             3409..4008
                     /locus_tag="ACG8LA_002677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFQ0204933.1"
                     /translation="MKSVEPIRDKKKIDAMKAILASGKYGQRNLVLFSIGINTAYRIS
                     DLRQLKLRDVLEISRGRVIVKERLAMKEQKTAKHNSVFISNKLRKVILDYVQSEFPEQ
                     LQAQDFSKYLFPSRKGADTPLTRQSLWRIIHEAGTAVGLKEIGPHSMRKTFGYFLYKQ
                     GTKTEIIQSLLNHSSQRETLRYIGITQEDKDTAVKSLDL"
     gene            4057..4773
                     /locus_tag="ACG8LA_002678"
     CDS             4057..4773
                     /locus_tag="ACG8LA_002678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HFQ0204934.1"
                     /translation="MNEEKQPNFPDKYHLSRKESVYLLKKNIVELVYNAGKFEGLNTT
                     LLQTEGIIKYNRANNVAVDDVLTVVNLKRGFEMLLNDVQEPLLETSKRINRIVAAEDA
                     LFPGEIRTGGVELSTIQGRYVPPMLTEDEVNNQYGEIMNQEISDTEKALRLFLFISKN
                     QIFWNGNVGTALLIANKIMFSNGLGLLSIPENVFMKFNELLSKYCNSNLLVNESNIIS
                     FLYEQCIFGINYLKIIQHTI"
     gene            4787..5566
                     /locus_tag="ACG8LA_002679"
     CDS             4787..5566
                     /locus_tag="ACG8LA_002679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002396205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="abortive infection family protein"
                     /protein_id="HFQ0204935.1"
                     /translation="MMTIDEAKQLATYFSVGSAGYILDFTNVTWNIFTKKIVGIEIQN
                     HYGGSKGVSFQKFLLDDQFDDSLKNRLIQSLKGIMDRDKKYESTEMNPIVQLLFEEVF
                     KEDTSTALRKMKFSSEIDLLYIRQLPIRIQTDIKNKDFDSVLTKANTLIDEVLKFIIE
                     NTEGPSVNINLFKSKELRKEVFGRLNIKTEKDMDNRIKALVGALNTLSDKILEMRNSQ
                     GDAHAHGSNRIVIKEEEAILVANSSMVLCEYVFTKYKGLNR"
     gene            5649..6005
                     /locus_tag="ACG8LA_002680"
     CDS             5649..6005
                     /locus_tag="ACG8LA_002680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HFQ0204936.1"
                     /translation="MEKISFETFKRPNGHDEFLEWLETLPKKDSAKLLRTIEETEKNG
                     MLVAQRLKWVKKLDTNLYELRSKVGSNIQRAIYFHVDNGRYVITHGFTKKTEKTPITE
                     LKHAKELREEWFTNDD"
     gene            5995..6261
                     /locus_tag="ACG8LA_002681"
     CDS             5995..6261
                     /locus_tag="ACG8LA_002681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFQ0204937.1"
                     /translation="MMIKKLIEEKKKDKDFAEAYDREGRKLETAVALYHAREEAGLTQ
                     AELAQKAHTTQSTIARIERGDNVSFDKLDDIARALGKKLVVEFA"
     gene            6420..6698
                     /locus_tag="ACG8LA_002682"
     CDS             6420..6698
                     /locus_tag="ACG8LA_002682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204938.1"
                     /translation="MKTINLIKVFIASPGDIAAKRNEVEETIYRWNIENTDNTKVILM
                     PIRWETNAIPTYVNNSSGQSVINKQIVENRVLLQSFKNKISFCIISSF"
     gene            complement(6695..>6868)
                     /locus_tag="ACG8LA_002683"
     CDS             complement(6695..>6868)
                     /locus_tag="ACG8LA_002683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010868911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HFQ0204939.1"
                     /translation="HRSIKRRHKLYQSLRTASTTIKGMETIRGIYKKSRKEGTLFGFS
                     VCTEIRILLGIPA"
BASE COUNT         2527 a          957 c         1333 g         2051 t
ORIGIN      
        1 taaaacaact gaatttgata ttctacacgc tctaatgtcc acacctaata aagtcttttc
       61 tcgtagtgat ttgatagaga aagttaaggg aatagaattt gatggactag ataggagcat
      121 cgattctcat ataaaaaact taagacataa aattgagaat gatgctaaat cacctatgta
      181 tattttgaca gtccatggta caggatacag atttggtggc cactaatgag aaaaagaacg
      241 ataaaaactc aattagctgt ttccttttta gcaatcgcaa cattaataat aggatcgatt
      301 agtttagtcg cattaagttt gatgaacaat cattttagta aatacgtgga agagcggcaa
      361 gaagatttgt tgaatcagta tgtatataca attgatttat tgtggttaaa tagtggggaa
      421 acatggaata gtgaagaact tgcagcacta tctgagaaag tattagagaa taatatttat
      481 ttttctatag aagacgaaca aggcaacatg gtttgggaac ttactggaaa agatttgaag
      541 tcagcacagg agaaactgaa aaaaatgcat tgaaagtttc tgagaaaaac agtgtgaaac
      601 tagacgaaac aatagaagtg aaaaagaagt taattaatga tggaaacgag tttggaaaag
      661 taacgtttta ttatttcgga ccttttgctt atacagagca cgatgccttg tttatctcca
      721 gtatgaaaca aagtttaatg tatgttgcaa ttgcagctct tcttgtatca ttcatacttg
      781 cttcgtggat ctctgctaga ttaggattgc cactaaagca tgtaagcgat tttacacata
      841 aattaactcg tggggaatat gctgataaaa tcccacaaga aacttcaatt attgaaataa
      901 attccttaat tgattcccta aatgatttaa gtaatcagtt ggagaaacag catgggcttc
      961 gaaaaagatt aactaccgat atttcacatg aattaagaac tccattagct acgcttaaag
     1021 gcaatgtgga aggaatgatt gacggagtct ggaaaataac tcccgagcgc ctacaatctt
     1081 gttatgacga aatagatcgt ctaactcgtt taattggaaa tatagaaata atcaacaaaa
     1141 ttgaagcaaa atatgatcat ttaaataaaa ctgagtttaa catatataag ttgattgaat
     1201 ccgttattga aaatttcgcc agcaaaattg agtcaaaaaa ccttcatgtt gaaatccaag
     1261 gggataacat caatatatct gcagataaag ataaaatgaa ccaagttgtt atcaatcttt
     1321 tgaataatgc tattaaattt acgcaaaagg agggaaccat taagttttct ataagtaaaa
     1381 ataaagacca tgttctttta attgttgaag acaacggcat cggtatagaa aaagatcagc
     1441 aacttcatat ttttgataga ttttatatgg ctgacccctc cagaagtaga gctttagggg
     1501 ggcaaggtat cggattagct attgtaaaga gcgttattga agcgcataaa ggtagtataa
     1561 ctgtaaaaag taaattaggt ctaggaacta aatttgttat aaagttacca tttcaataaa
     1621 ggaggagagt tatttgtttc aaaaacagat aaaaattgct aaactagtat gtgaatgttg
     1681 ggcaaaaaaa atattttttc aactgatttc gatagatagt gtcgaaaaag ttcatttaga
     1741 tatcttatca aattctgtag taatcttttc taagaaggac ttatcaatag ctacaattaa
     1801 aaaagaagtt tttggattac aaatttatga gatgacctaa atgtgattaa ttaaaggagg
     1861 atgaagacag tgaaaaagat gacaaaatta gtatttgcaa gtcttggaat tattgtattt
     1921 ttaggagcgt gtagcaatca aagtgaatcg aataattcta atagcacaaa cgaggaatcg
     1981 acttctacag cgtctagtga aatgaatagt atggagggaa tgaatcacga aggtatggtt
     2041 ccttcttcaa tgaaagatgc tgcgaaccct aaattcccgg tgggaagtaa tgttatactg
     2101 ctaggcgatc atatggaagg gatgaaaggt gcaaatgctc aagttgtagg ggcctttgat
     2161 actacaatgt atgaagtaag ctatgagcca aaaactgggg gaccaatggt taacaatcat
     2221 cgatgggtag tacaagaaga gttaaaagat actgagactg tagcaaatga gggcgatact
     2281 gttatcttga atgccgatca catggatggg atgatgggag ctgaagcaaa agtagataaa
     2341 tctattacag gaactgttta cgttgttaat tacactccaa ccgatggtca agaagaagtt
     2401 aagaatcata tgtgggtaac tgaagatgag atggaatatg acgaaaataa tgagtaattt
     2461 tatatactaa accaacaagc tggtacatgg tcttcgtatt ctcaacatga ggaatatgag
     2521 ctctttgtta ataaggactg atgagttgtg caaaatcaaa tctgggtcag aacgaacctc
     2581 attctggctc agatttttgg ctcttcgaca tttagtgctg gtagagagac aactgaaaat
     2641 ttagtcataa ccagttaggc agagtgctta actggttttt gttcgcattt attattcttt
     2701 tgatattggc tgcttgccct tcaattttat ttggtttctt aatcaactct tcatataacc
     2761 ccaaatcata tattaatgag gtgcctccta ttcctataaa tctatctctt ctttaatagt
     2821 atgagaaaag tctactcttg tagatttaaa ttgtcaacaa aaaatttaca gatgtaaatg
     2881 ataagttgaa tagagaaaga taaattattt ttttggtatt catataaggt taattatgta
     2941 ttatcacaaa atgattgttg tcgaataact aaaagtgtca aaacaatgat gaaatcattt
     3001 agttcttata aattagacaa gagaaaataa atattccata tctactttat tggatccata
     3061 acatgactaa attctgaata ctttttaaag cttatcattt ggtaaaactg aatataagtt
     3121 aattatatag actgaaaatt ttgaattttc agaatagaat aacttaaaag tactgacaaa
     3181 ttttttaaag gggcaatatt aatgttctga gataatcaaa tcttaccgaa aatatcaaaa
     3241 gtccaatgtg acacaattgg attttgtcac attcgttaaa atcgctccat ccttagaggc
     3301 tctaatagga aatcactttt cttttagcgc cttttttcta tagcttgttt aaatgtgact
     3361 tattatctgt tataatcgta ttaagtaaca tttgagaggt gtctaaaaat gaaaagcgtg
     3421 gaaccgattc gcgacaaaaa aaagatcgat gccatgaagg ccattttggc ttccggaaaa
     3481 tatgggcaac gaaatttggt gcttttttcg atcgggatca atacagccta tcgaatctcc
     3541 gatttaagac agttaaaatt aagggatgtg ctagaaattt cccgtgggcg ggtgatcgtc
     3601 aaagaacgtc tggccatgaa ggaacaaaaa acggccaaac acaattcggt cttcatttcg
     3661 aacaaattgc gaaaagtgat tcttgattat gttcaatccg aatttcctga gcagttgcaa
     3721 gcacaagact tcagcaagta tttgtttcca agtcgaaaag gagcagatac gcctttgacc
     3781 cgacaaagcc tttggcggat cattcatgaa gcaggaactg cagttgggtt aaaagaaatt
     3841 ggtccccatt cgatgcgtaa gacctttggc tattttttat acaagcaagg aaccaaaaca
     3901 gagatcattc agtcgctgct aaaccattct tcacaacggg agaccttacg ctatattgga
     3961 atcacccagg aagacaaaga tactgcagta aagagtttgg atttatgaca gaataatgcc
     4021 ctatataata gaaggaaaaa ttcaagaggt gagaaaatga acgaagaaaa gcagcctaac
     4081 tttcctgata aatatcactt atctcgcaaa gagtctgtgt atttattgaa gaaaaacatt
     4141 gtagaactgg tgtataatgc ggggaaattt gaagggttaa atacaacgtt gttacaaaca
     4201 gaagggatta ttaagtataa tcgggccaac aacgtggctg tagatgatgt cctgaccgtc
     4261 gttaacttaa aaagaggctt tgaaatgctt ttaaatgacg tacaggagcc cctgttagag
     4321 acaagtaagc ggattaatcg gatcgttgca gcagaggatg cgctttttcc cggtgaaata
     4381 cgaaccggtg gggtagaatt atcgacgatt caaggaagat atgtgccacc aatgttaact
     4441 gaagacgagg taaacaatca atatggtgag ataatgaatc aagagatatc agatacggaa
     4501 aaagccctgc gactgtttct attcatttcg aaaaatcaaa tattctggaa tggtaatgtg
     4561 ggtacagcct tgttgattgc gaataagatt atgtttagca acggtttagg actattatca
     4621 atacccgaaa atgtatttat gaaatttaac gaacttttat caaagtattg caacagtaat
     4681 ctattagtca atgagtcaaa tattatatca tttttatatg aacagtgtat ctttggtatt
     4741 aattatttga aaataatcca acatacaatt taagaggtat aagtaaatga tgactataga
     4801 cgaagcaaaa caattagcaa cttatttttc agttggttca gcgggatata ttttagactt
     4861 tactaatgta acgtggaaca tatttacaaa gaaaatcgta gggattgaaa tacaaaatca
     4921 ttatgggggc tcaaagggag tatcctttca aaagtttctg cttgacgatc aatttgatga
     4981 ttcgttaaag aatcggttaa tccaatcttt aaaaggtatt atggatcgag ataaaaaata
     5041 tgaatctact gaaatgaatc ccatagttca gttgcttttt gaggaagtat ttaaagaaga
     5101 tacttcaact gcattaagaa aaatgaaatt ttcaagcgag attgatttac tttatattcg
     5161 gcagctaccc attaggattc aaacagatat taaaaacaag gattttgact ctgttttgac
     5221 aaaagcaaat actttaatag atgaagttct aaaatttatt attgaaaata ccgaaggacc
     5281 gagtgttaat attaatttat ttaagtcaaa agaattaaga aaagaagtat ttggccgcct
     5341 caatattaaa actgaaaaag atatggataa tagaatcaaa gcccttgttg gagcactcaa
     5401 tacattatca gataaaatac tcgaaatgag aaatagtcaa ggagatgctc atgcacatgg
     5461 ctcaaataga atagtaatta aggaagaaga agcaattctt gttgcaaatt cttctatggt
     5521 tttgtgcgag tatgtgttta ctaagtataa aggattaaat agataataaa atgcatattt
     5581 tatagtatac aattcgaatt tttatgttat atactataat ataaaatcaa tatatgatat
     5641 aattgggtat ggaaaaaata tcttttgaaa catttaaaag acccaatggt catgatgaat
     5701 ttttagaatg gttggaaaca ttaccaaaaa aagatagtgc gaagctttta cgtacaatag
     5761 aagaaacaga aaagaatggg atgctagtag ctcaacggtt gaaatgggtg aaaaaattag
     5821 acactaattt gtacgaatta agaagtaagg taggatcaaa catccaaaga gccatctatt
     5881 tccatgtgga caatggaagg tatgtcatta ctcacggatt tactaaaaaa acggagaaaa
     5941 caccaataac tgaactcaag catgcaaaag aacttagaga ggagtggttc acaaatgatg
     6001 attaaaaaat tgattgaaga aaagaaaaaa gataaagatt ttgcagaagc atatgaccgt
     6061 gaaggaagaa aactcgaaac tgcggttgct ctttatcatg ctcgggagga agcagggcta
     6121 actcaagcgg agcttgcaca aaaagcacat acaactcaat ctactattgc tcgaattgag
     6181 agaggggata acgtatcttt cgataaactt gatgatatcg ccagggcatt aggtaaaaag
     6241 ctggtagtag aatttgctta aaagcgagtt gaaaatatat ctataatagg ctcctaacta
     6301 atcaattagt ttagtgggcc tttttttact agatagataa aggttgtact atagtgtaaa
     6361 agacaataaa ttttatacta aaattacttt aaagagaact agagagaaag gtacaataaa
     6421 tgaaaaccat aaatcttata aaagtattta tagcatcacc aggtgatata gcagcaaaaa
     6481 ggaatgaagt agaagaaacc atatatagat ggaatataga aaatacagat aatacaaaag
     6541 tgattttgat gcctatacga tgggaaacta atgcgattcc tacttatgta aataatagct
     6601 ctgggcaaag tgttattaat aaacaaattg tagaaaatag ggttctgctg caaagtttta
     6661 aaaataaaat cagtttttgt attatttctt cattttaagc tggaattccc aataatatcc
     6721 tgatttcagt gcagactgaa aagccgaaga gagtgccttc ttttcggctt ttcttgtaga
     6781 ttcctcgaat ggtttccatc cctttaattg tggtggaagc tgtacgtaga ctttgataca
     6841 atttatgtcg acgttttatc gatcgatg
//
LOCUS       DAZKKZ010000101         6782 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.104, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000101 DAZKKZ010000000
VERSION     DAZKKZ010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6782)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6782)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6782
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.104"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            15..905
                     /locus_tag="ACG8LA_002684"
     CDS             15..905
                     /locus_tag="ACG8LA_002684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ArsR family transcriptional regulator"
                     /protein_id="HFQ0204940.1"
                     /translation="MQLQINEESLPVYEALASKTRIKIIQLLSKKKMNVKDLAKELGV
                     SSAITTMHVKKLEEANIIKTEKVGQQKISSLRVDKIDISFPEKIFNAFDTKETSIPIG
                     HYTNYAIEPTCGLATIHDFIGKVDEPRYFMDPRRMDARILWFTSGFVEYQAPNFLNTE
                     DTLEMLEVSVEISSEFPFSNDNWPSDITFSLNGVELGTWTSPGDFADIRGKYTPDWYP
                     DNLNQYGLLKTIRITKHLTNMNGEPLSNITINDIPKEQDTWHLRIEVKDDAKHVGGCT
                     LFGKGFGNYDQDIKLKVYYS"
     gene            complement(978..1802)
                     /gene="nadE"
                     /locus_tag="ACG8LA_002685"
     CDS             complement(978..1802)
                     /gene="nadE"
                     /locus_tag="ACG8LA_002685"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003952 - NAD+ synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_function: GO:0004359 - glutaminase activity [Evidence
                     IEA];
                     GO_function: GO:0008795 - NAD+ synthase activity [Evidence
                     IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HFQ0204941.1"
                     /translation="MSLQTEIINELGVKPTIDPKEEIRKSIDFMKAYLKKYPFLKTFV
                     LGISGGQDSTLAGRLAQLTMEEMREETKDENYQFIAVRLPYGEQADEEDAKAALDFIQ
                     PDVSLRVNIKPAVDAQVQVLSEAGVGISDFNKGNIKARQRMITQYAVAGERAGAVLGT
                     DHAAENITGFFTKFGDGGADILPLFRLDKRQGKQLLQALNAPEKLYTKIPTADLEDGK
                     PMIADEVALGVTYNEIDDYLEGKEVPAQAQEKIEAWWNKTQHKRHLPISVLDDFWK"
     gene            complement(1814..3286)
                     /locus_tag="ACG8LA_002686"
     CDS             complement(1814..3286)
                     /locus_tag="ACG8LA_002686"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004516 - nicotinate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HFQ0204942.1"
                     /translation="MNNTYPDDSLTLHTDLYQINMMQTYWELGRADLHAVFECYFREM
                     PFNHGYAVFAGLERLVNYLENLTFNDSDIAYLRGLEVYPEGFLEYLQNFEFKATVRSA
                     REGELVFANEPLIQVEGPLAHCQLVETALLNMVNFQTLIATKAARIKSVIGEDPLLEF
                     GTRRAQELDAAVWGTRAAYIGGADATSNVRAGKIFGIPASGTHAHSLVQSYGNDYEAF
                     MAYAKTHKDCVFLVDTYDTLKSGVPSAIRVAKELGDKINFQGVRIDSGDMAYISKRVR
                     EQLDAAGFTEAKIYASNDLDEATILNLKMQKAKIDVWGVGTKLITAYDQPALGAVFKL
                     VSIEDDEGKMMDTIKLSSNAEKVTTPGKKQVWRITRNFDGKSEGDYVTLWDEDPREEE
                     AIFMFHPVHTFINKTVRDFTARPVLQDIFIEGKRVYELPALNEIKEYTKENLDSLWEE
                     YKRDLNPQKYPVDLSTECWNHKMAIMERMKKSVAELHTEA"
     gene            complement(3923..4285)
                     /locus_tag="ACG8LA_002687"
     CDS             complement(3923..4285)
                     /locus_tag="ACG8LA_002687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HFQ0204943.1"
                     /translation="MKLIETPVNSNLNIKTFYPKVVEFFFGNTAINYYKLFSLDRTQL
                     LLVDTYDKKQVVMINTKKKITRQEIDYAIHHVLKMTREDVKVHVGVKQELERAGIQFK
                     RPNKDIVVIEQKNTKDSI"
     gene            4508..5260
                     /locus_tag="ACG8LA_002688"
     CDS             4508..5260
                     /locus_tag="ACG8LA_002688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HFQ0204944.1"
                     /translation="MEYTIKKMSEISGVSPRTLRFYDEIGLLKPARINSSGYRIYGKK
                     EVDRLQHILFYRTMAFKLDDIQEVLDNPSFDHQKALIKHQQMLLEKRAQIDTLLTTVQ
                     QTLDMYEGGRKMSDKEKFEGFKQQKLKENEESYGQEIRQKYGKKKVTASNEKWMNMDK
                     ETYEEMQTVEKQMLFDLTLYLKEPEDESLADRIFQAHKKWFSYSWPEYQPKAHKGLGM
                     MYEADERFTAYYDERSGHGAAKALNEIIQKKA"
     gene            complement(5400..6323)
                     /locus_tag="ACG8LA_002689"
     CDS             complement(5400..6323)
                     /locus_tag="ACG8LA_002689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFQ0204945.1"
                     /translation="MANIRDIAKLTGYSVSTISRVINGHPYVDEEKRKEILAVMKEVD
                     YIPNANARQLSYGKTKSIGVILPYTNHPYFDQLISGIIEAAFDYDYKVTLLPTGYHKE
                     KERRYLEEFAAKAFDGLIITSRANTLDDLLAYQKYGPLVFCEEIKGKQASCVFIDREQ
                     SITEGLTYLKQQGIKQLGITLGRSGRLSYNSKITLQLCHQLFPSFDESLVFWDCIDAE
                     KGKQAGFFFKELGVDGVFTNSDMVAAGILQSYLQDKTPVVIGRDNLLISELLGFPTID
                     HHLEACGEMAFQLFLTEKKDKVKIPYTFIQR"
     gene            complement(6338..6610)
                     /locus_tag="ACG8LA_002690"
     CDS             complement(6338..6610)
                     /locus_tag="ACG8LA_002690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204946.1"
                     /translation="MNTYVEITDGTTNNYFYAFVEFKGSVLTLYSFQGLNRNIVKEIP
                     MNEIENLTKDIYWGGQRISFSHEGKMYQFFECGPAVVDYLQENLFV"
BASE COUNT         2071 a         1350 c         1161 g         2200 t
ORIGIN      
        1 aagaggtgat atatatgcaa ctacaaataa acgaagaatc cttaccggta tatgaagcat
       61 tagctagtaa aacaaggatc aagatcatcc agctactttc caaaaaaaag atgaatgtca
      121 aagatttggc aaaagaactt ggagtgagca gtgctatcac gacgatgcac gtgaaaaagc
      181 tagaggaagc aaacatcatc aaaacagaaa aagtaggaca acaaaaaatt tcgagccttc
      241 gtgtcgataa aatcgatatc agttttccag aaaaaatatt caatgctttt gatacgaaag
      301 aaacatcgat acctattggt cactatacaa attatgcaat tgaaccaaca tgcggtttag
      361 ctacgatcca tgattttatc gggaaagtgg atgaaccacg ctattttatg gatcctcgaa
      421 ggatggatgc ccgcattctc tggtttacca gcggatttgt cgagtatcag gcacctaatt
      481 ttttaaatac agaggataca ttggagatgt tggaagtttc tgtggaaatt tcttctgaat
      541 ttcctttttc aaatgacaat tggccttcag atatcacttt cagcctaaat ggtgtggagc
      601 taggaacatg gacgagccct ggagattttg ctgatatccg cggtaaatat acgcctgatt
      661 ggtatccaga taatcttaat caatacggct tgctgaagac gatccgaatt accaaacact
      721 tgacgaatat gaatggagaa cccttgtcaa acatcacgat caacgacatc cctaaagagc
      781 aagacacttg gcatttgcga atcgaagtga aagacgatgc caaacatgtg gggggctgta
      841 ctttatttgg taaaggattc ggtaattacg atcaggatat caaattaaaa gtttactaca
      901 gctgatattt ttcttttcta ttttataaaa caaaaacagc caatccctat gaagggacgg
      961 ctgtttttgc tttattgtta tttccagaaa tcatccaaaa cggaaattgg caaatgtcgt
     1021 ttatgttgtg tcttgttcca ccatgcttcg attttttctt gtgcttgagc gggaacttct
     1081 tttccttcta gataatcatc aatttcatta tatgtgacac ctagtgcgac ttcatctgca
     1141 atcattggtt tcccatcttc aagatctgca gtcggaattt ttgtgtataa tttttccggt
     1201 gcattcaatg cttgaagcaa ttgtttccct tgtcgtttgt ccaaacggaa taatggcaaa
     1261 atgtcggctc caccatcacc aaatttcgtg aagaatccag taatgttttc tgcagcatga
     1321 tctgtcccta atacggctcc tgctctttct ccagctacgg catattgcgt aatcatacgt
     1381 tgacgtgctt tgatatttcc tttgttaaaa tcgctgattc ccacacctgc ttcgcttaat
     1441 acttgtactt gtgcatcaac agctggtttg atatttactc gcagactaac atcgggctgg
     1501 ataaagtcaa gagcagcttt tgcatcttct tcatctgctt gttcaccata aggaagacga
     1561 acagcgataa attgatagtt ttcatctttt gtttcttcac gcatttcttc catcgttagt
     1621 tgcgccaaac ggcctgctaa agtagaatct tggccgccgc tgatacctag tacaaaagtt
     1681 ttaagaaacg gatatttttt caaatatgct ttcataaagt caatactttt acgtatttct
     1741 tcttttggat caattgttgg tttgacacct aattcattga taatttctgt ctgcaggctc
     1801 atttattctc ctcctatgct tctgtatgaa gttctgctac gctttttttc attcgttcca
     1861 tgatagccat tttatggttc cagcattcag tagacagatc gactgggtat ttttgcggat
     1921 tcaagtctcg tttatactct tcccatagtg aatctagatt ttcttttgta tattctttga
     1981 tttcgtttag tgcaggtaat tcgtaaactc tttttccttc gataaagata tcttgtaaaa
     2041 ctgggcgagc tgtaaagtct cgaacagttt tattgataaa cgtatgcact ggatggaaca
     2101 tgaagatagc ttcttcttct cgagggtctt catcccataa tgtcacgtag tctccttcag
     2161 atttcccatc aaaatttcga gtgatgcgcc acacttgttt tttccctgga gtagttactt
     2221 tttctgcatt gcttgataac ttgatcgtat ccatcatttt tccttcatca tcttcgatcg
     2281 atactagctt gaatactgca ccaagggctg gctgatcata ggctgtgatc aattttgtcc
     2341 caacacccca tacatcaatt ttagcttttt gcatctttaa attcaaaatc gttgcttcat
     2401 ccaagtcatt cgaagcatag atttttgctt ccgtaaatcc ggctgcatct aattgttccc
     2461 gaacacgctt agatatatag gccatatctc cactgtcgat gcgtacgcct tggaagttga
     2521 ttttgtcacc taattctttc gccacgcgaa tcgcacttgg cacacctgat ttcaacgtat
     2581 cataagtgtc gactaagaac acgcagtctt tatgggtttt agcgtaggcc ataaatgctt
     2641 cataatcatt tccataagat tggactaacg aatgagcatg ggtcccgcta gctggtatcc
     2701 caaatatctt cccagcacgt acattgcttg ttgcatctgc tccgccgata tatgccgctc
     2761 tagttcccca gactgctgca tccagttctt gtgcccgtct agttccaaat tccaatagtg
     2821 gatcttctcc gatgacagat ttgatacgag ctgcttttgt cgcgatcaac gtttggaaat
     2881 tgaccatatt caacagtgct gtttctacta attggcagtg cgctaaaggc ccttccactt
     2941 ggattaatgg ttcatttgca aaaactagtt ctccttcacg agcagaacga actgttgctt
     3001 taaattcaaa attttgtaaa tactccaaaa aaccttcagg atagacttct aatccacgca
     3061 agtaagcaat atcggaatca ttgaacgtca gattctctaa ataattgact aaccgttcca
     3121 atcctgcaaa aaccgcgtat ccgtggttaa aaggcatttc tcgaaagtaa cattcaaaaa
     3181 cagcatgtaa atcagctcga cctaattccc agtatgtctg catcatattg atttgatata
     3241 gatccgtatg cagcgtcaaa ctgtcgtctg ggtaagtatt attcatcttg tattactcct
     3301 cttggcaagt tttcatttcc tacccattat aacaaaaaaa attaatagga aaagaaatct
     3361 tccatttttt ctgaaaaagc acatgtttta cggatatttc ttgctaaaaa tgaactccat
     3421 ctgctaaaac tatcctttct tattggtatt taacctaaac gagaaagaat acttatttta
     3481 ttcaatgtat ccgagacacg aagaaattag cgttttctat ttttcttact tgataaaata
     3541 agtagatttt cctactacaa tcgtagccgt taagataccg atgattgaac aaatataacc
     3601 aaatgtctct acaacataat caatggcaaa agtttttgaa gcaataatac gtctttcctt
     3661 ttttgcttct tatccccaaa gaaacggata taacttatta tgtattgaat ttttttggaa
     3721 aggcgaatta tgacaagata taccttgcgt tgaaaaaact cgcggaaaaa atatcacacg
     3781 tttttaaaaa gatacaaagt aagaaagcag ctgtcaatag aatggaaaca aaaatggcga
     3841 gacatcaatc agtctcgcct tgttttttat tgtatacatt agatatggag caggttacca
     3901 taaagatgat tattagtcgt tattaaatag aatccttcgt atttttttgt tctatcacta
     3961 caatatcttt atttggacgt ttgaattgta ttccggcacg ttctagctcc tgtttcactc
     4021 ctacatggac tttgacatct tctcgtgtca tttttaaaac gtgatgaatc gcatagtcga
     4081 tttcttgcct tgtgattttt ttcttcgtat tgatcatcac gacttgcttt ttatcatatg
     4141 tgtctaccaa tagcagttgt gttcgatcta acgaaaataa tttgtaataa ttaatagccg
     4201 tattcccaaa aaagaattcc actactttag gataaaatgt cttaatattt aaattactat
     4261 tcacaggtgt ttcgattagc ttcatctcat tcctcttttc tatatagtcg atttagatcc
     4321 aatcttaagt tatgttacca tctttcctag cattaaggaa tcggttacaa ttgaaccttt
     4381 aaagacaaaa ggatttacct tttatcactt aatagtataa cataatttcg tgagaaaaaa
     4441 atacaatttt ttcttgacca tctcgttacg taaaggatta tgcttacatt tgtcaggagg
     4501 aaaaataatg gagtacacaa taaagaaaat gtcagagata tcaggagtca gtccgagaac
     4561 cttgcgcttt tatgatgaga ttggactgct aaaaccagct aggatcaatt cttcaggtta
     4621 tcggatttat ggcaaaaaag aagtcgatcg tctgcaacac atcttatttt atcgaacaat
     4681 ggcattcaag ttggatgata tccaagaggt cttagacaat ccatcttttg accaccagaa
     4741 agctttaatc aagcatcagc aaatgttgct ggaaaaacgg gcacaaatcg ataccctctt
     4801 gacaactgtc caacagacac ttgatatgta cgaaggagga agaaaaatga gtgacaaaga
     4861 aaaatttgaa gggtttaaac aacaaaagtt gaaagaaaat gaagaatcct atggacaaga
     4921 gattcgacaa aaatacggaa aaaaaaaggt tacagcatcc aatgaaaaat ggatgaatat
     4981 ggataaagaa acgtatgaag aaatgcaaac tgttgaaaag cagatgttat ttgatctcac
     5041 tctttactta aaagaaccag aagatgaaag cttagcagac cgtatcttcc aagctcataa
     5101 gaagtggttc tcttacagct ggcctgaata tcagccaaaa gcgcataaag gactaggaat
     5161 gatgtacgaa gccgatgaac ggttcactgc atattatgac gagcgaagtg gtcatggtgc
     5221 agcaaaagct ttaaatgaaa ttatccaaaa aaaggcgtaa tcttttacat gatccaacaa
     5281 aaaagtacac gtaaaatgac ctaataacaa aacagcagac acccaagtta gatttttatg
     5341 ctaacttttg gtgtctgctc cattctttca caagtttttt catcctactt taaatatatt
     5401 catcgttgaa taaacgtata aggtattttc actttatcct ttttttctgt aagaaacaat
     5461 tgaaatgcca tttctccgca agcttccaga tggtggtcga tggttgggaa accaagaagc
     5521 tcgctgatca gcaaattatc gcgtccaatc accactggtg tcttatcttg cagatagctt
     5581 tgcaagatgc ctgctgcaac catatccgaa tttgtaaaga caccatcaac tccaagctct
     5641 ttaaaaaaga agcctgcttg ttttcctttc tctgcatcta tacaatccca aaaaacaagt
     5701 gattcatcaa aagatggaaa aagttgatga catagctgca aagtgatttt tgagttataa
     5761 cttagcctgc cacttcgccc caacgtgatg cccaattgct ttataccttg ctgcttcaaa
     5821 taagtaagac cttctgtaat tgattgttct cgatcaataa agacacagct tgcctgtttt
     5881 cccttgattt cttcacaaaa aactagaggt ccatattttt gatatgccaa taaatcatct
     5941 agtgtattgg cacgagacgt aatgatcaat ccatcgaaag ctttagctgc aaattcttca
     6001 agataccttc gctctttttc tttatgatag cccgtcggta aaagtgtcac tttgtaatca
     6061 taatcaaacg ctgcttcaat gatcccactg atcaactgat caaaatacgg atgattggta
     6121 taaggcagaa tcactccaat gcttttcgtt tttccataac ttaactgtct ggcatttgca
     6181 ttagggatat aatcgacttc tttcatgacc gcaagtattt ctttcctttt ttcctcatct
     6241 acatatggat gtccattgat tacacgtgaa atagtagaaa ctgaataacc tgtgagcttt
     6301 gcgatatctc gaatgtttgc cactgctgct tcgccaccta tacaaaaaga ttttcttgta
     6361 aatagtctac cacagctgga ccgcattcaa aaaactgata catttttcct tcatgcgaaa
     6421 aactgatccg ctgcccgccc caatatatat cttttgtcaa attttcgatt tcattcattg
     6481 gtatttcttt tactatattc ctattcaacc cttgaaaact gtacaacgtt aatacggatc
     6541 ccttgaactc gacaaacgca taaaaataat tgttcgttgt gccatctgtt atctctacat
     6601 aagtattcat tgcaagccct ccttttgata ctttgagtat agtgtatgaa acgcgtctca
     6661 tagcaaggag tttgttttgc caaagaaaag ttttattcct ctttcattat taccaaagtc
     6721 tcttatttta aattgaatac attataatga tactgtaaat atatctttat tattagtgaa
     6781 tg
//
LOCUS       DAZKKZ010000102         6643 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.105, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000102 DAZKKZ010000000
VERSION     DAZKKZ010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6643)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6643)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6643
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.105"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(1..859)
                     /locus_tag="ACG8LA_002691"
                     /pseudo
     CDS             complement(1..859)
                     /locus_tag="ACG8LA_002691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element ISEfa10 family transposase"
     gene            1102..1557
                     /gene="tnpA"
                     /locus_tag="ACG8LA_002692"
     CDS             1102..1557
                     /gene="tnpA"
                     /locus_tag="ACG8LA_002692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HFQ0204947.1"
                     /translation="MSNDDKSLAYTRWNCKYHIIFTPKYQRKVIYGQLRKDLGKILRK
                     LCEMKDVEIIEAHAMLDHIHMLVRVPPKICISSFMGYLKGRSAVLIHEQHANLKYKYG
                     NKSFWSKRYYVSTVGLNQKTNEKYIREQEADDRIRYIISKREYVEPFKK"
     gene            1822..1920
                     /locus_tag="ACG8LA_002693"
                     /pseudo
     CDS             1822..1920
                     /locus_tag="ACG8LA_002693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558064.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(2143..2373)
                     /locus_tag="ACG8LA_002694"
     CDS             complement(2143..2373)
                     /locus_tag="ACG8LA_002694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="resolvase"
                     /protein_id="HFQ0204948.1"
                     /translation="MDEAMDHPLLNKFIKDLILQIFSMIDEQEPTESKRHRAQGIIKI
                     AKRMFSIKGVLSYTVLIQKIPNHLVYKNNVED"
     gene            complement(2603..3421)
                     /locus_tag="ACG8LA_002695"
     CDS             complement(2603..3421)
                     /locus_tag="ACG8LA_002695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HFQ0204949.1"
                     /translation="MSYIYLIKENYPFLTKSEKKVADFILNSGKTIIYSTMSDIKKNT
                     KVGDATIIRFCQKIGFSGFSDLKIEIAKEDFSQKKEHPTSVKYYDEIANSLTEALYST
                     IRLLDEEKLNEAIKMITQSKNIYIFGVGSSGNTSLDLENMFLRVGVQAKAVLDPHFQA
                     QVASLLTVNDLVIIFSLSGKTKDTYDSLKIAKKNGAKIIAITNYIHSPIGKSADLVLQ
                     TAIEEFLNGGSLAGKISQLYICDLLVHGYEQNNNIDSVELREKVLRSIIDKSIE"
     gene            3582..4271
                     /locus_tag="ACG8LA_002696"
     CDS             3582..4271
                     /locus_tag="ACG8LA_002696"
                     /EC_number="5.1.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009385 - N-acylmannosamine-6-phosphate
                     2-epimerase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006051 - N-acetylmannosamine metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019262 - N-acetylneuraminate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HFQ0204950.1"
                     /translation="MDKKRFLDLISKGLIVSCQALPGEPFYKEEESLMPYFALAAQRA
                     GAVGIRANSVRDIIEIRKCVSLPMIGIIKRDYPPESPFITATMREVDELVETGVEVIA
                     LDCTLRNRHDGLSINSFITKIKEKYPHQLFMADISTFEEGKNAYKAGIDFVGTTLSGY
                     TEESKKQDGPDIDLIKKLVEEGICVIAEGRIHTPEQAKEIKKIGVAGIVVGGAITRPQ
                     EIASRFVKALS"
     gene            4285..5787
                     /locus_tag="ACG8LA_002697"
     CDS             4285..5787
                     /locus_tag="ACG8LA_002697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFQ0204951.1"
                     /translation="MFKKFSQLGRAFMLPIAILPVAGLLLGLGGALTNESAINAYPFL
                     DQPWLHTILSIMSYAGNAVFANLALIFAIGIAVGLANGDKGTAGLAGGVAYLVYTATI
                     SGFLELFSAKDATLDTGVVGSIVVGGTVAFLHNRYRKIELPQFLGFFGGSRFIPIVSS
                     LAAIIIGSFFYLIWPPIQNGLVVAGEQIAQMGSLGTFLYGFLLRLTGAVGLHHTIYPL
                     FWYTSLGGTETVAGSTIAGAQNIFFAQLADPNHTGLFTYGTRFFAGRFATMMFGLPAA
                     CYAMYRAIPKKNRKKNGGLYFSGALTSFLTGITEPVEYMFLFVAPWLYVIHAFLDGLS
                     FYFADILNIRVGNSFSGGLIDFLLFGVLQGNDKTNWLKLIPFGIAWAFIYFFVFTFFI
                     KKFKVAIPGMEEESEVHSEKVINKNTSLHEESLIIIEALGGKENIESVEACATRLRVA
                     VTNGEIIQKQTIKDTGATAVFEVKGGIQAVFGGKADLLSQEINQILGKDN"
     gene            5800..6276
                     /locus_tag="ACG8LA_002698"
     CDS             5800..6276
                     /locus_tag="ACG8LA_002698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HFQ0204952.1"
                     /translation="MFEIFKKKKQETFYAPCSGKIISITEVNDPVFSQKLLGDGFAVI
                     PDGSKIYAPLAGRVTNIFPTKHAINIKSNSGIDYLIHIGIDTVELQGEPFSICVQEND
                     EVTPETSLVDVDFDKIIKSGKDTSVIVVFPEKNQFNDLIIDNGRIAHGNSCGKITF"
     gene            complement(6373..6483)
                     /locus_tag="ACG8LA_002699"
                     /pseudo
     CDS             complement(6373..6483)
                     /locus_tag="ACG8LA_002699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         2172 a         1032 c         1204 g         2235 t
ORIGIN      
        1 acttgtcctc gataagaatt gtagcgccgt gatttacgtg tgtatgtcgt tacttttatt
       61 cctagcttct tgatcaggcg ctgaactttc tttttattga tagagaaacc gcggtttctt
      121 agttcattgg tcatccgtaa acagccataa tccttgtgct tctcccgaac tttaagcatt
      181 tccgcttcaa tctcttgatc tggattttta cggtccaatc gtttttgcca gtacataaag
      241 attgccttag ggaactttaa agtttctaga agctcaacta atttaaacgg tcctcggagg
      301 cttgcgatga ttcgtgcgat tgcttcattc gtcgttgttg ggcttcctgt tttcgcagct
      361 tcctcaattc ttttaaaaag gcattttcaa tttgaaggga acggactcgt ttctccaact
      421 cctcgatgcg ttcacgttct ttagacgttg ctttagttgt agattttttc ttatttttgg
      481 gttcattttt cttagacaag ataggtggac atcctttcgt ttttgagagt ccatcgatcc
      541 caccctcacg gaattgacgc atccaactag cgatcaaatt agggttgttc atgttaagtg
      601 tgttggcaac ttcacgatag gacagctcac ttgttagata taactctatc gcatccagct
      661 taaattgaac agaatatttt ttcttttgtc gctttcttac tagaccctct tcaccaaatt
      721 cttgataggc attgatccag cgcttcactt gtgatggagc cttaatggaa tatttctttg
      781 ccagataatc acttccgcct ttaccatcca agtaatcatg aacgatcttt aatttaagtt
      841 caaaagtata cttagccata aaaaataccg acctccaaaa gttagatttt ttggtctaac
      901 ttttgggggt cggtacaaaa cttaaaagtt ttagaccctt ttattttctt aatgacttca
      961 gtcagttttg tgcgtaaagc gtgcgaaaca agaaaaccgc gcgtttctac gcgtggaaga
     1021 agtatcttta gcgataaaaa ctcctttcga tatactagtg agtggctacc aaccgctcat
     1081 cagatcgaaa ggagtttttt catgtcaaat gacgataaaa gtttagcata tactcgttgg
     1141 aattgtaagt atcatattat ttttacacca aaatatcaac gaaaagtaat ctatgggcaa
     1201 ttacgaaaag atcttggaaa aatacttagg aagttgtgcg aaatgaaaga tgtggaaatc
     1261 atagaagcac atgcaatgct agatcatatt cacatgcttg ttcgagtacc accaaaaata
     1321 tgtatatcca gttttatggg gtatctgaaa ggtcgtagtg cggtactaat ccacgagcag
     1381 cacgcaaatc tcaaatataa atacggaaac aaatcctttt ggtcgaagag atactatgtg
     1441 agtacagtcg gattgaatca aaagacaaat gaaaaataca tccgtgaaca agaagctgat
     1501 gatcgcattc gatatattat aagtaaaaga gagtacgtag aaccatttaa aaaataaaga
     1561 gaagtaagtg agtgaagatg agcagttggc ggtcttttaa aaatcccctt ttaaggggca
     1621 gcgagtgtcg accccttcta gggggattaa aaatacaccc gtcctcacgg gtgtatgggt
     1681 tactgataga cttgatttta actggtgtca gaaacttatg tccagaaagg gtgatgaaat
     1741 tttggcaatt tacggctatt caagaattag cacaagcaac caagattaca aaacacaaat
     1801 tcaaacatta gaaaatgctg gcgcagaaat aatcttccta gaaaatcact ggattatcga
     1861 acacctttgg aagtattttt gagttacgta agtattgatg atctgtctaa cttaatttga
     1921 caattaagag tatatttact tcagatggta aggcaacaaa ataaaataca ataggcagat
     1981 gaactaataa ataaaatctg tattaaatac agataaatta atataaaaat caaaaggatc
     2041 ataaactttt aacaagtgat gaaatgggtg gaaattgatt cttatagaca gtttgtctca
     2101 taacattgaa gtattttgca attttagcat tgaaacactt ttttaatctt caacgttgtt
     2161 cttataaaca agatgattgg gaatcttttg aattaacact gtatagctta gaacaccctt
     2221 tatagaaaac attcgcttag caatcttaat aattccttgt gcccgatgtc gtttagattc
     2281 agtaggttcc tgctcatcga tcatggaaaa aatttgaagg atcagatcct taataaattt
     2341 atttaagaga ggatgatcca ttgcttcatc catactcgat aaactagtga taatgagcta
     2401 cacgtttttc tttcaagttg atcaatagct tccacgataa aaatatcttt agataaaatc
     2461 aagaaccgta ggaactacag ggatatttgg tcaataagag ccaccgctat tagtaaaaaa
     2521 taagctatca agtatgctct catcccaaga attgcctact tcaatcgtta aaaaccgtta
     2581 ggtttagcta agtgggggta gttcactcaa tacttttatc aataatagag cgcaaaactt
     2641 tttctcttaa ttcaactgaa tcaatattat tgttttgttc ataaccatga actaatagat
     2701 cacaaatata aagttgtgat atttttccag ctaaagatcc accattaaga aattcttcaa
     2761 tggctgtttg taaaactaag tctgcagact ttcctatagg tgaatgaata tagttagtta
     2821 tagcaataat ttttgcgcca ttttttttag ctattttcaa tgaatcataa gtatctttcg
     2881 ttttcccaga taaagaaaaa atgattacta aatcattaac tgttaataaa gaagcgactt
     2941 gggcttgaaa atgagggtct agtacagctt ttgcttgaac tcctacgcga agaaacatat
     3001 tttctaaatc aagactagta tttccactag atcccactcc aaatatatat atgttttttg
     3061 attgagtgat cattttaatg gcttcattca atttttcttc gtctaaaagc ctaatagtgg
     3121 aatagagagc ttctgttaaa ctattagcaa tttcatcata gtactttaca ctagtcggat
     3181 gttctttttt ttgactaaag tcttcctttg caatttcaat ttttaaatca gaaaaaccag
     3241 aaaaaccaat tttttgacaa aagcgaataa tagtagcatc gccaactttt gtgtttttct
     3301 taatatcact catcgtacta taaataatag ttttcccaga atttaaaata aaatcagcga
     3361 cttttttttc agacttcgtt aaaaatggat aattttcttt aattaaatag atataactca
     3421 tacaaactcc tctacaattt caacttttct ccattatact ccaaaataat aaaaaaaact
     3481 cctaaatact ccatttttat ctttactttt atgaaagcgg atgctatatt gtttttggag
     3541 ttgttatcca aaaataataa aaaattggag tgtttaggat aatggataaa aagaggtttt
     3601 tagatcttat ttcaaaaggt ttgattgttt cctgtcaagc attacctggt gaaccatttt
     3661 acaaagagga agaaagttta atgccttatt ttgctttggc tgctcaaagg gctggagcag
     3721 ttggtatacg tgcaaattct gttcgagata ttattgaaat tagaaagtgt gtatcattac
     3781 caatgattgg aattattaaa agagattatc caccagaatc tccattcatt actgccacta
     3841 tgagagaagt agatgaatta gtagaaaccg gtgttgaggt aatcgctctt gattgcactc
     3901 ttagaaatcg acatgatgga ctatctataa attcttttat tactaaaata aaagaaaaat
     3961 atcctcatca gttatttatg gcagatattt ctacatttga agaaggcaaa aatgcatata
     4021 aagcaggaat agattttgta ggaactactt taagtggata tactgaggaa agtaaaaaac
     4081 aagatgggcc agatatagat ttgattaaaa aattggtaga agaagggatt tgtgtaattg
     4141 ctgagggaag gattcatact ccagaacaag caaaagagat aaaaaaaata ggagttgcag
     4201 gtattgttgt gggtggtgct attactcgac cacaggaaat tgcatcaaga tttgttaaag
     4261 cattaagtta gggggagaaa taaaatgttt aaaaaatttt cacaattagg acgcgctttc
     4321 atgttaccaa ttgctatatt accagtagcc ggattactat tgggactggg aggagcgtta
     4381 acaaatgaga gtgctataaa tgcttatcca tttttagatc aaccgtggtt gcatacaatt
     4441 ttaagtatta tgagttatgc tggaaatgca gtttttgcaa acctagcact aatttttgca
     4501 attggtattg ctgtaggact tgcaaatgga gataaaggaa cagctggttt agctggtgga
     4561 gtagcttatc tagtatatac tgcaactatt agtgggtttc ttgaactttt ttcagcaaaa
     4621 gatgcaacac tagatacagg tgtagtggga tcaattgttg ttggtggtac tgttgcattt
     4681 ttacacaatc gttatagaaa aattgaatta ccacaattct taggtttttt tggaggatca
     4741 agatttattc cgattgtttc tagtttagct gcaatcatta ttggttcttt cttttattta
     4801 atttggccac caattcaaaa tggtttagta gttgctggtg aacaaattgc ccaaatgggt
     4861 agtttaggaa cttttttata tggtttttta ttgcgtttaa caggtgctgt tggactacac
     4921 cacaccattt accctttgtt ctggtataca tctttaggtg gtaccgaaac tgtagctgga
     4981 tcaacaattg ctggagccca aaatattttc tttgcccaac tagctgatcc aaaccacact
     5041 ggtctgttta cttatggtac tagatttttt gcaggaagat ttgcaacaat gatgtttgga
     5101 ttaccagcag catgttatgc aatgtatcgt gcaattccta agaaaaatcg taaaaagaat
     5161 ggtgggcttt attttagcgg ggcccttaca tcatttttaa ctggaattac tgaaccagtt
     5221 gaatatatgt ttttatttgt tgctccttgg ctttatgtga ttcatgcatt cttagatgga
     5281 ttatcttttt attttgctga tatcttaaat attcgtgtag ggaattcctt ttcaggtggt
     5341 ttgatcgact ttttattatt cggtgtactt caagggaatg acaaaactaa ttggttaaaa
     5401 ttaattcctt ttggtattgc atgggcattt atatatttct ttgtttttac attctttatc
     5461 aaaaaattta aggtagctat tcctggaatg gaagaagaat cagaagttca ttctgaaaaa
     5521 gtaataaaca aaaatacatc attacatgaa gagtctctta tcattattga agctcttggt
     5581 ggaaaagaaa atattgagtc tgttgaagct tgtgcaactc gtttgcgtgt tgctgttacg
     5641 aatggggaga ttattcaaaa acaaacaata aaagacactg gtgcaactgc tgtcttcgaa
     5701 gtgaagggtg gcatccaagc tgtttttgga gggaaagctg acttattaag tcaagaaatc
     5761 aatcaaatat taggaaaaga taattaggag gtttttaata tgtttgaaat tttcaaaaag
     5821 aaaaaacaag aaacttttta tgcaccttgt tccggaaaaa tcatttccat cacagaagta
     5881 aatgatcctg tcttttcaca aaaattacta ggtgatggtt ttgccgtcat acctgatggt
     5941 tcaaaaattt atgctccatt ggctggtcga gtaacaaata tatttcctac taaacatgct
     6001 attaatataa aaagcaactc aggcattgat tatttgattc atattggaat tgatacagtt
     6061 gaattacaag gagagccttt ttcgatttgt gttcaagaaa atgatgaggt tactcctgaa
     6121 acctcgttgg ttgatgtgga ttttgacaaa ataataaaat ctggtaaaga tacttctgtt
     6181 atagttgttt ttccggagaa aaatcagttc aatgatttaa taatagataa tggtcgaatt
     6241 gctcatggga attcatgtgg aaaaatcact ttttaaaaaa gtgtatataa aaagctataa
     6301 aataagctaa ataggatatt tgtcaaatga agttggtgaa cagaaagaac tgttttcttt
     6361 ctgttcattt ttttatttta ttagtaatga ttccccatgc caaatcatga tccgtaattt
     6421 aaagttataa aagcttcgaa atccattggc atttcgttgg aataccttga tatgattatt
     6481 caaatataaa atatagagag aagagagaga gggaagatat ttataaaggg caaagttatg
     6541 tttactcaac ttaggaaata gaaatagatc aatttatatt ctcttgtcaa tcgaatatga
     6601 accttagcac tatataccaa atatagtaaa atgctgaaag atg
//
LOCUS       DAZKKZ010000103         6635 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.106, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000103 DAZKKZ010000000
VERSION     DAZKKZ010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6635)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6635)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6635
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.106"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            57..914
                     /locus_tag="ACG8LA_002700"
     CDS             57..914
                     /locus_tag="ACG8LA_002700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HFQ0204953.1"
                     /translation="MEEKLIKKDEIIMGLLVPRANTYTIPLTKRQLIAKRYQRITRAI
                     NREFWNSESDTAHSLYVGSYGRGTAISTSDIDIIVELPMAEFDRFKNYLSNGPSKLLQ
                     VIKNAFQEILPNSDIRADGQVVKINFHDGIKFEIVPAFNEKDYWGESKGFIYPDSNMG
                     GNWKATNPKKEQEAMKLKNTKSNNLLYATCKHFRHVRDTEFTSYHLSGIVIDSFVYEA
                     MGNWKFVENNSGGQNISSVSYETALLEYYNSHKVMGGLNLYSPGSNQFVNSDSSIICL
                     EKVLKKIAL"
     gene            934..1494
                     /locus_tag="ACG8LA_002701"
     CDS             934..1494
                     /locus_tag="ACG8LA_002701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLATT domain-containing protein"
                     /protein_id="HFQ0204954.1"
                     /translation="MGDEKKRLEVQLREAYGRVTYTYTTHLKQADNIISDNKILRCLQ
                     IGLSALTTGGVLSTIITDNSELTFVAGLCSTISLGLNLYFKNFDLAEEAKNHQIVADK
                     LWLIREEYVSLLTDLNRLSVEDIVKKRDQLMNETHEAYKNAPKTNSKSYESAQKALKS
                     EEEQFFTEEELDKMLPEHLRKKSSKY"
     gene            2383..3150
                     /locus_tag="ACG8LA_002702"
     CDS             2383..3150
                     /locus_tag="ACG8LA_002702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="JAB domain-containing protein"
                     /protein_id="HFQ0204955.1"
                     /translation="MRDRILEVNQEMVNKLTNISGNYEKYDGTLLDNYIFHDTQNIRI
                     GRSKPRAFILIKEKYLNEWNSTYEMVMTDNFEKVLDFRNALLGSDMGNSSLESIEVEN
                     KTENEGEGLIKNVLKIEQKYISEDRSFYRVTSSVGLANFATNLIGNNASESLLVMCLN
                     TKNEVIAYSEVFKGGINQSVAIPREIFQLALLNNSAKIAVSHNHPSGYEFPSENDKSF
                     TTNLKNAGKTIGIELLDHIIVTSKNTSYYSFQENGSL"
     gene            3176..3721
                     /locus_tag="ACG8LA_002703"
     CDS             3176..3721
                     /locus_tag="ACG8LA_002703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204956.1"
                     /translation="MGERTQALITVKYGNSKTKASVSIHYQWGYGRYMLMDVLNQGIY
                     LINKAYDLRDKSREELAKGIFDRSTGVINFVTYESGVSAYDETGFGGRYEPYQETIED
                     VMKFSDNNDGYAHLEMVFDENGFSLDDKTRLRLFDFEGQQIGLNKFCESGKEFATKDF
                     IKGYRLLLENYGINLEEESVK"
     gene            3722..4288
                     /locus_tag="ACG8LA_002704"
     CDS             3722..4288
                     /locus_tag="ACG8LA_002704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204957.1"
                     /translation="MFEKRKDQFPNLEAKSQKVIDGEMIELFQKSYGTIETTASCKYY
                     FQGKRNTFKGFADSDEELAKKIIDWLVSSEHVAREDTVRTTINGEVLTGTRCVCCNHE
                     FVEDEGCYRINEYGDFICQSCHEIEFPTERSWFEYMLQDYEMETENGEVVFCTKEELS
                     KRSDDEIEDWCVWLVGTDDCVAYYTTAE"
     gene            4303..4551
                     /locus_tag="ACG8LA_002705"
     CDS             4303..4551
                     /locus_tag="ACG8LA_002705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204958.1"
                     /translation="MEGMDFIDHEDLIDFGYTWKGMVGISRSLANAFYERNYAVYVLY
                     DDNTESLVDEEYKLDLENVLYGIEKEDLAKYIFSWLGQ"
     gene            4570..4809
                     /locus_tag="ACG8LA_002706"
     CDS             4570..4809
                     /locus_tag="ACG8LA_002706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204959.1"
                     /translation="MTKFKSKGMQWCSYYYVGNDEELLRKAKQKGYPDKMLKQIGYYM
                     PEERIEKESCKVLFDSEQLLVLLTQNKLICQFENN"
     gene            4826..5410
                     /locus_tag="ACG8LA_002707"
     CDS             4826..5410
                     /locus_tag="ACG8LA_002707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204960.1"
                     /translation="MNENKMVLSEYARLRTINWLNGMQSSGAFDGFDEENMDFESLSN
                     EDIRYYFIEWYFTEPDEEVEDEPELILERQRILFSEQDSKRLYGLYDLQLKGLKAQYV
                     ADSYDDMVEQGADRVVTYSEDDEEEWENYSDDEICFNDGYMPIEITEEEYDKVSDSDE
                     IGMCTVVSGLDIDVQRVEVAYQKMKERIKSKVES"
     gene            5517..5798
                     /locus_tag="ACG8LA_002708"
     CDS             5517..5798
                     /locus_tag="ACG8LA_002708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HFQ0204961.1"
                     /translation="MKVKNPKEKSRIQVGIDKDLKENAEMILEELGLNPTTAITILYK
                     QVVARGEFPVEIKLSEEEKQGIRLQQLTMDMPVDVLDTDEKLEEWFNEA"
     gene            5788..6129
                     /locus_tag="ACG8LA_002709"
     CDS             5788..6129
                     /locus_tag="ACG8LA_002709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HFQ0204962.1"
                     /translation="MKPNEIVTVYVAFTDKNGGKRRPILVVSDKEDRVEFFGITSQYE
                     NKSDQIKRVYFPIAEWEKVGLKKQSWIDVGSLKAIPKSRENISFKKVGMLSAIDTKKL
                     NRFIERLQRKV"
BASE COUNT         2499 a          864 c         1370 g         1902 t
ORIGIN      
        1 taaaagtaat atataaaata aattgcttga agtattatat ttagatatca taatttatgg
       61 aagaaaaatt aattaaaaag gatgagatta taatggggtt actggttccg agagctaata
      121 cttatactat acctttaacg aaacgccaat taattgctaa aagatatcaa aggattacta
      181 gagccatcaa tagagagttt tggaattctg aaagtgatac tgctcacagt ttatacgtag
      241 gttcttatgg gagaggaacg gcaattagta ctagtgatat agatataata gttgaattac
      301 cgatggcaga atttgacaga ttcaaaaatt atttatcaaa tggcccgtct aagttattac
      361 aagttataaa aaacgcattt caggaaatac taccaaatag tgatattaga gctgatggac
      421 aagttgttaa aataaatttc catgatggaa tcaaatttga aatagttcca gcttttaatg
      481 aaaaagatta ttggggtgag tcaaaagggt ttatttatcc agattcaaac atgggaggga
      541 actggaaagc tacaaatccc aaaaaagagc aagaagccat gaaattaaag aatacaaaaa
      601 gtaataattt attatatgct acgtgtaaac attttcgaca tgtacgagat acagaattta
      661 cgagttatca tctttcagga atagtaattg acagtttcgt atatgaggct atgggaaatt
      721 ggaaattcgt tgaaaataac agtgggggtc aaaacattag ttctgtatct tatgagacag
      781 ctttattaga atactataac tcacataaag ttatgggcgg tttaaattta tactctcctg
      841 gaagcaatca atttgttaat tctgatagta gtatcatatg tttagaaaaa gtattaaaaa
      901 aaatagcttt ataaagtttt atggaggaac aacatgggag acgaaaaaaa gcgcttggaa
      961 gttcaattac gtgaagcata tggacgagta acgtatactt acaccactca tttaaagcaa
     1021 gccgataata ttatttctga caataaaatt ttaaggtgtc ttcaaattgg tttgtcagcc
     1081 cttactactg gaggggtact tagtaccatt attactgata atagtgagtt aacctttgtt
     1141 gctggattat gttcaacaat ttctcttgga ttaaacttat actttaagaa ttttgatctt
     1201 gctgaagaag ctaaaaatca tcaaattgtt gccgataaat tatggttgat cagagaagaa
     1261 tacgtaagct tactaacaga tttaaatcgt ttaagtgttg aagatattgt gaaaaaaaga
     1321 gatcaattaa tgaacgaaac tcatgaagca tataaaaatg cccctaaaac aaatagtaaa
     1381 agctatgaat cagctcagaa agcattaaaa tctgaagaag agcaattttt tacagaagag
     1441 gaattggata agatgttacc agagcatctt agaaaaaaga gttctaaata ttgaactctt
     1501 tttttatgct taaaattctc ttgtaatttt tctattcatc tatatttaag aagaaatatg
     1561 atgatagaaa catctcctaa agccaccgca agccgttcta agcatagctt agcccgacat
     1621 tgctagatat gctcatctca ccatgaacgt ttcctaaagc caccgcaagc cgtcctagcc
     1681 attgcctagt ccgacatcgc tagattagtg catctcgcca taaaagtttt ctaaagccac
     1741 cgcaagccgt tctaagcata gcttagcccg acattgctag atatgctcat ctcaccatga
     1801 acgtttccta aagccaccgc aaaccgtcct agccatcgcc tagtccgatt ttgcttgatc
     1861 ggttccattt ctgtttattt agtgggtcaa caccgtaatc ttaaatagcc atcgcctatt
     1921 taagattact aggtctgctt tgaaggtaaa aagtctttca ttcttcaaga cttttaggct
     1981 ttcaagctac gcctgaaagc attgaaattc atcgctcttt atttggtttt gccatttata
     2041 attccttacg cccattatct ttttcgcctg tcataccttg tcagaagtgt ttagagctta
     2101 tctcatcttt ggattaatac aagtggcgta aatttttttc taaacgcaag cgttacgaaa
     2161 ataatttact taaacacttg tattaatccg gcagataaga acgcattcta atcactcccg
     2221 acaaggcaag acaggcgaaa aagataaata aatgaacgaa aggaagaaac ataaaatgca
     2281 aaaccaaata gcgatgaaga aaaaaccacc tccctctaaa acaatccaaa caaaaaagaa
     2341 ttttgaaaaa ccaaaaatca aaaacagaaa gaagcgttca acatgagaga tagaatttta
     2401 gaagttaatc aagaaatggt aaacaagtta acaaatatca gtgggaacta tgaaaagtac
     2461 gatggtactt tacttgataa ctatattttt cacgatacac aaaatatcag aattggcaga
     2521 agtaaaccga gagcgttcat tctcatcaaa gagaaatatt tgaatgaatg gaatagcacc
     2581 tatgaaatgg ttatgactga taactttgaa aaggtattgg atttcagaaa tgctttgttg
     2641 ggttctgata tgggaaatag cagtcttgaa tctattgaag ttgaaaacaa gaccgagaat
     2701 gaaggtgaag gattgattaa gaatgtcttg aaaatcgaac aaaaatatat cagtgaagat
     2761 agaagttttt atagagtcac aagctcggtt ggtctagcaa actttgctac taacttaatt
     2821 ggaaacaatg ctagtgaatc tttgctagtg atgtgtctga atacaaagaa tgaggtcatt
     2881 gcttatagcg aagttttcaa aggtggaatt aatcaatcag tagcgatacc aagagagatt
     2941 tttcaactag ctttgctaaa caattcagca aaaatcgcag tatcacataa tcatccgagc
     3001 ggatatgaat ttccaagtga aaatgacaaa agttttacta cgaatttgaa aaacgcagga
     3061 aaaacaattg gtattgaatt gttagaccat atcatcgtaa caagtaaaaa cacaagctat
     3121 tactcatttc aagaaaatgg ttctttataa aaattagaga aaagaggaaa acaagatggg
     3181 cgaaagaaca caagcgttaa ttacagtcaa atatggtaac agcaaaacga aagcaagcgt
     3241 gtcgattcat tatcagtggg ggtatggtcg atatatgctg atggacgtat tgaatcaagg
     3301 aatttattta atcaataaag catacgactt acgagataaa tcaagagaag aattagcaaa
     3361 aggaatcttt gatagaagta caggagttat caattttgtc acctatgaat ctggagtgag
     3421 tgcttatgat gaaacagggt ttggtgggcg ctatgaacct tatcaagaaa cgattgaaga
     3481 tgtgatgaag ttttcagata acaatgatgg ctatgctcat ttagagatgg tgttcgatga
     3541 aaatggattt agtctagatg ataaaaccag attgcgattg tttgattttg agggtcaaca
     3601 gataggacta aacaagtttt gtgaaagcgg aaaagagttt gctacgaaag attttattaa
     3661 gggatacaga ttattgctag aaaattatgg aataaaccta gaagaagaga gcgtgaaata
     3721 agtgtttgaa aaaagaaaag accagttccc taatttagaa gcgaaaagtc aaaaagtgat
     3781 tgatggtgaa atgattgaat tattccaaaa aagttatgga accatagaaa ctaccgcaag
     3841 ttgcaaatac tactttcaag gaaagagaaa cacgtttaaa ggctttgccg attctgatga
     3901 agaattggca aagaaaatca ttgattggct tgtcagcagt gaacacgtag caagagaaga
     3961 taccgttaga acaacgatta atggggaagt cctaacaggt actagatgtg tttgttgtaa
     4021 tcatgaattt gtagaagatg aaggttgcta ccgaatcaat gaatatggtg attttatttg
     4081 ccagagttgc cacgagatag aatttccaac cgaaagaagt tggtttgaat acatgctaca
     4141 agattatgag atggaaacag aaaatggtga agtagttttt tgtaccaaag aggaattgag
     4201 taagagaagc gatgatgaaa ttgaagattg gtgtgtgtgg ttagtaggga cagatgattg
     4261 cgttgcatat tacacaacag cagaatagga gtgtgaatca gcatggaagg aatggatttt
     4321 atagatcatg aagatttgat tgattttggt tatacatgga aaggaatggt aggtattagc
     4381 agaagtcttg ctaatgcctt ttacgaaaga aattatgcag tctatgtcct ttatgatgac
     4441 aatacagaaa gccttgttga tgaagagtat aaattggatt tagagaatgt tttatatggg
     4501 atagaaaaag aagatttagc aaaatatatt ttttcatggt tgggtcaata aacgaaagag
     4561 ggtagcaaca tgacaaaatt caaaagtaaa ggtatgcaat ggtgttctta ttattatgtt
     4621 gggaatgatg aagagctttt gagaaaagcc aaacaaaaag gttatccaga taagatgtta
     4681 aaacagattg gctattacat gccagaagag agaatagaaa aagaatcttg taaggttctt
     4741 tttgatagtg aacagctatt agttttgtta actcaaaata aattgatttg tcaatttgaa
     4801 aataattaat atggggtgaa gaaccatgaa tgagaataag atggtattaa gtgaatacgc
     4861 aagattgaga accattaatt ggttgaatgg tatgcaaagt agtggcgctt ttgatggatt
     4921 tgatgaggag aatatggact ttgaaagttt atcgaatgag gatattagat attattttat
     4981 cgaatggtat tttacagaac cagatgaaga ggtggaagat gaaccagaat taattttaga
     5041 acgtcaaaga attttattca gtgaacaaga tagtaagagg ttgtatggtt tatatgactt
     5101 acaactgaaa ggattaaaag cgcagtatgt tgctgatagt tacgatgata tggtagaaca
     5161 gggggcagat agggttgtca cttattcaga agatgatgaa gaggaatggg aaaactattc
     5221 agatgatgag atatgcttta atgatgggta tatgcctatt gaaatcaccg aagaagaata
     5281 tgataaagtg tcggatagcg atgagattgg tatgtgtacg gttgtaagtg gattggatat
     5341 agatgtccaa agagtagagg ttgcatacca gaagatgaaa gaacgtataa aaagtaaagt
     5401 agaatcttga tttgattgga ttgtttgcaa agtagctaat taagagtata atataatcat
     5461 aaatgtagtt aatggatata ataatgagta tattatactc aaaagaggtg aacgaaatga
     5521 aggtaaaaaa tccaaaagaa aaaagcagaa ttcaagtcgg aatagacaag gatttaaaag
     5581 aaaacgcaga aatgatattg gaagagctag ggttaaatcc aacaacagca atcacaatcc
     5641 tttataagca agtggtcgct agaggtgagt ttccagtaga gataaagcta agcgaagagg
     5701 aaaagcaagg aatcagattg caacagctaa ctatggatat gccagttgat gttctagata
     5761 cagatgaaaa gttagaagag tggttcaatg aagcctaatg agatagtaac ggtctatgtt
     5821 gcatttacag ataaaaatgg tggtaaaaga agacctattt tggtggttag tgataaagaa
     5881 gatagagtag aattttttgg aatcacaagt caatatgaga ataaatcaga ccaaataaag
     5941 agagtgtatt ttcctattgc agaatgggaa aaagtaggtc taaagaagca atcatggatt
     6001 gacgtagggt ctttaaaggc tattcccaaa agccgagaga acatatcatt taaaaaggtt
     6061 ggtatgctat cagctattga tacgaaaaag ctaaataggt ttatcgagag attacaaaga
     6121 aaagtctaac aaggcttttc tttttttgtt tatatgtata ttaagatata cgtttatata
     6181 aacgtattta tgtatattaa aatacacgta aatatatacg tgattataaa aattaagaaa
     6241 atattaagta ttgttaaata gtgataatta gtaatatacg aattataaga tacattttat
     6301 atttaatgta tgtaaataaa taaaatgact gacggatatt gaatagtaat aaataacaat
     6361 aattcagacg gatacagtga gtgaagtagc ttgctacgaa cgaacaggca gaatgaaacg
     6421 gtagtttcat tagagcaagt cgcttgcgac gtagcgttac cactgatgta actggcaagt
     6481 tacatagaga gagtttgctt gcaaacgaac gttacccact tgaatagaaa acaaaaataa
     6541 catattagtg aattttgaat aggagccaca actcaaccaa ccgcttgcgg tgggtgagtc
     6601 ccacggagga aaagacgaac gaacggtcgc gtagc
//
LOCUS       DAZKKZ010000104         6569 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.107, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000104 DAZKKZ010000000
VERSION     DAZKKZ010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6569)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6569)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6569
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.107"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            127..579
                     /locus_tag="ACG8LA_002710"
     CDS             127..579
                     /locus_tag="ACG8LA_002710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000751236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204963.1"
                     /translation="MKKTILSIFSVFTILIGGYFLLNLDSVNSNAQIKDQRVAEHNNK
                     KMSLTKNIYSMSDEELYKEFGDLSGEQLEESIPGISDSDKIVVLSAGGQLMGDGKSEL
                     VSYKQNHRQFIDVNTDSNAISIKDLKELLNSKRNELKQIKETNSVELE"
     gene            593..1282
                     /locus_tag="ACG8LA_002711"
     CDS             593..1282
                     /locus_tag="ACG8LA_002711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000718009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204964.1"
                     /translation="MKKIFGVSVGLLMMLTFGNAVYAAEKEVISDPEQYASRYFADFE
                     EEDKVLALPEGGFLKGEAKIVSMDNPDIIQGSYNSETDPASVSVTEAKKIVAEKFKND
                     IETTPIMPRGAFPPDVGTSGHLLVLAGGGSYKSQPFSGAGWRFGGMGVKPADGTGNFL
                     RWKSYIDDGRVGNVNQANATKSGSIQGMALYAREGFKYFAPNGPGWTMNIGIYYTYNP
                     VAGTYYVVQNI"
     gene            1407..3758
                     /locus_tag="ACG8LA_002712"
     CDS             1407..3758
                     /locus_tag="ACG8LA_002712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase domain-containing protein"
                     /protein_id="HFQ0204965.1"
                     /translation="MDEMVLSTQKWLNKKYSNVTGFDKVPENGRTGWPTIYGLIEGLQ
                     VELGITNLVANFGPTTEKMYDNQVTPKWGKNLPKNIVFLIQGAFWCKGINPGGFDGVY
                     TPYLDTAVKELQTDAGFNGSAVTGVLDAKWAKALFDMSAFVLVPGGDSKIRKMQQWLN
                     VNYLEYTGIMPCDGIYQRNSNQALIFALQAELGYSPSEATGSYGNGTTSKTYPVSEGN
                     SGNYVRIIQYGLYVNGYFEDGTFDGIFTKYMGLEVLAFRKFMVLPEYTEIADVVVIKG
                     LLSSAGDIRRSADGADTSTQLTRSQIQTLVDNDIKIVGRYLTGTVGIGKDERNKYLTT
                     EELNNIFSKNLSVFPIYQDGGAALAYFTYDRGLSDGKKAIDAAKNLNIPLTTVIYFAV
                     DLDMLGEEILAYAGEYFKGVSAVMSYSGYQTGVYGTRNVCSQIINNGYASFAFVSDMS
                     TGYSGNLGFPMPRQWSFDQFVEFTIGSGNGAVGIDLIATSGRDSGFNELSNDTNNDNY
                     IAKYNQKVINQMVRAYQYLSQAGLDNPWNPHLTFYRYVNYSGLSWDIISSPVTEHDRK
                     IYDEYRNKLTNSEGLYNYFIDPNTGSIIGLPHLIVTLQSQMFLADTINDSVSDFAGWL
                     GDLMTCWGEVKKLGIQMEQGVFALVGTAAGGTFSLEDLYQDVDAVNVYTLAKRNSDST
                     ALSALKTYYCDKGAIDRFNQFVKNRFGSSDKIASVTNSLLENDETVDILGVGIISFFI
                     DKIVNNSLGTDFTYLDFIGDEGKVANGFSEKIIQFQENRSKLN"
     gene            3838..4233
                     /locus_tag="ACG8LA_002713"
     CDS             3838..4233
                     /locus_tag="ACG8LA_002713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204966.1"
                     /translation="MMIMEEIEWNNLTQNNKNNSGCGIIFMFVIVLGIVVLLITVKIV
                     DYFANTPEEQIQRKLPEFERVPPYDPRDNSFQVKKLKESPNEMWFEVTVESSDFKEKK
                     KEYNYIVKAKVSKRFIFNPKLEIYSVVIE"
     gene            4558..5175
                     /locus_tag="ACG8LA_002714"
     CDS             4558..5175
                     /locus_tag="ACG8LA_002714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFQ0204967.1"
                     /translation="MRKFFYIRVSSYDQSIERQLISAKELGIPEEYIFVEKASGKDFK
                     RPEYQLMKRMFRKGDLLYLQSLDRLGRNKQMILEEWRELTKEKQIDISVLDMPLLDTA
                     SYKQLDGLETLISDLILQLLSYMAEDERKRINSRQREGVEAAKQKGVKFGRKKIALPP
                     EFPAIYSDWKAGKITAVYAMDQLGMKRNTFYRRVKEYEHTLHHFS"
     gene            5216..5515
                     /locus_tag="ACG8LA_002715"
     CDS             5216..5515
                     /locus_tag="ACG8LA_002715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BRCT domain-containing protein"
                     /protein_id="HFQ0204968.1"
                     /translation="MDLTNQRVVFTGTLQQMTRTQAIGLVHSLNGHCQSSVTSKTNFL
                     VCGQYSKSLFDDSLYTKKEQTARDLIALGHEITILSEVEFYALISQQLKEWQRYL"
     gene            5549..5716
                     /locus_tag="ACG8LA_002716"
     CDS             5549..5716
                     /locus_tag="ACG8LA_002716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HFQ0204969.1"
                     /translation="MKRKSYDRWGIEITSFNRNIAFHVECDCGELAKSVYQKNYFYCP
                     KCHRRYGVHGT"
     gene            complement(5761..6366)
                     /locus_tag="ACG8LA_002717"
     CDS             complement(5761..6366)
                     /locus_tag="ACG8LA_002717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFQ0204970.1"
                     /translation="MGKIGYIRVSSQDQNLDRQLAMMEGLNIDKLFQEKASGKDTERP
                     EFQKLLNYIREGDCVIVTSLDRLGRDYEDIKNTVAFMKQKKVALKILDAQFLDFNTGN
                     ELLDTAMFDMFLSLLSYIAQNEREKIRERQRQGVLLAQKAGRYKGRPIEYSINSTDPQ
                     KRLVFKTVVDMLKQGIPVAEIAKENGISRPTIYKIKKANDL"
BASE COUNT         2265 a          910 c         1285 g         2109 t
ORIGIN      
        1 attcctcctg ctatcttttt ctattattct atcttatttg atagtagatt taaaactttg
       61 caacagaacc aattatctta tcgtagatat atattataaa tttaataaga aagcgaggtg
      121 agaatcgtga aaaaaacgat actaagtatt ttttcagtat ttacaatatt aattgggggc
      181 tattttcttt tgaatttaga ttctgttaat tcaaacgctc aaataaaaga tcaaagagta
      241 gctgaacata ataataaaaa aatgagtttg accaaaaata tctattctat gtcagatgaa
      301 gaattgtata aagaatttgg tgatttatcc ggggaacagt tagaagaaag tattccagga
      361 attagtgact cagataaaat tgttgtcttg tctgctggtg ggcaattaat gggagatggc
      421 aaatccgaat tagttagtta taaacaaaat cacagacagt ttattgatgt taatactgat
      481 tccaacgcta tttcgattaa ggatctaaaa gagcttttaa atagtaaaag aaatgaatta
      541 aagcagataa aagaaactaa ttcagtggaa ttagagtaaa ggaagattca ttatgaaaaa
      601 gatttttggt gtttctgttg ggctacttat gatgttaaca tttggaaatg cagtatatgc
      661 tgctgagaaa gaagttattt cagatccaga gcagtacgcc tcacgatact ttgctgattt
      721 tgaagaagaa gataaagtac ttgcattgcc agaaggtggt tttttaaaag gggaagctaa
      781 aattgtatct atggataatc cagatataat tcaaggttca tataattcag aaactgatcc
      841 tgcttcagtt tcagtgacag aagcaaaaaa aattgttgct gaaaaattca aaaatgatat
      901 tgaaactact ccaattatgc ctcgaggagc atttccaccc gatgttggta ctagcggaca
      961 ccttcttgta ctagcaggag gaggaagcta taaatcacag ccatttagtg gtgcgggatg
     1021 gcgttttgga ggtatgggtg taaaaccagc tgatggtaca ggcaactttt tacgttggaa
     1081 atcctacatt gacgatggaa gagtaggaaa tgtaaatcaa gccaacgcaa ctaaatctgg
     1141 ttctattcaa ggaatggcat tgtatgctcg tgaaggattc aaatactttg caccaaacgg
     1201 gcctggttgg acaatgaata taggtattta ttacacttat aatcctgttg caggtacgta
     1261 ttatgttgtt caaaatattt aataaaacag cacaaagaga tttctttgtg ctgttttatt
     1321 atttttagtt gttgacaaac actaaaatat aaaatataat caacacataa acgaacgtat
     1381 gttcggcaag aaagcagggg atttttatgg atgagatggt tttaagtact cagaaatggc
     1441 taaacaagaa atacagtaat gttacagggt ttgataaggt tccagaaaat gggcgaacag
     1501 ggtggcctac aatctatgga cttattgaag gactacaagt agaacttggt attactaatc
     1561 tagtagctaa ttttggacct accactgaaa aaatgtacga taatcaggtt actcctaaat
     1621 ggggcaaaaa tctacctaaa aatattgtat ttcttattca aggtgccttt tggtgtaagg
     1681 ggattaatcc aggtggcttc gatggggtat atactccata tttagatact gctgtaaaag
     1741 agttgcagac tgatgcaggg tttaatggaa gcgctgtaac tggagttttg gatgcgaaat
     1801 gggccaaagc gttatttgat atgagtgctt ttgttcttgt tcccggcgga gatagtaaaa
     1861 ttagaaaaat gcagcaatgg ttaaatgtaa attatttaga atacacggga ataatgcctt
     1921 gtgatggtat ttatcaaaga aattcaaatc aagcattaat ttttgcatta caagctgaac
     1981 taggatattc tcccagtgaa gcaacagggt cttatggtaa tgggacaact agtaaaactt
     2041 atcctgtgtc tgaaggtaac tcgggaaact atgtaagaat aattcaatat ggattatatg
     2101 ttaatggtta ttttgaagac ggtacattcg atggtatttt cactaaatat atgggtttag
     2161 aagtactggc attccgaaaa tttatggtat tgcctgaata tactgaaata gcagatgttg
     2221 ttgtaataaa aggactattg tctagcgctg gagatattag aagatctgca gatggcgcag
     2281 atacttctac gcaattaact agatctcaaa tccaaacatt ggttgataat gatataaaaa
     2341 tagttggtag atatcttact ggtactgttg gaattggaaa agatgaacga aataagtatc
     2401 taactacaga ggaattgaat aatatttttt ctaaaaattt atctgtgttt cctatctatc
     2461 aagatggagg tgcagcatta gcttatttta cttatgatcg tggcttatca gatggtaaga
     2521 aggctataga tgcagcaaaa aatctaaata taccattaac aacagttatt tattttgctg
     2581 ttgatctaga catgttaggg gaagaaattc ttgcatatgc tggagaatat tttaaggggg
     2641 tatctgctgt aatgtcatat agcgggtatc aaacgggtgt ttacggaaca agaaatgttt
     2701 gttctcaaat aatcaataac gggtatgctt cgtttgcatt tgtttcagat atgtcgactg
     2761 gttatagtgg gaatttaggt tttcctatgc ctagacaatg gtcttttgat caatttgttg
     2821 aatttaccat aggaagtggc aacggagctg ttggtatcga tttaatcgct acatcgggta
     2881 gagatagcgg atttaatgag ttatcaaatg atactaataa tgataattac attgccaaat
     2941 acaatcagaa ggttataaat cagatggtac gtgcgtatca atatctatca caagctggtc
     3001 ttgataatcc ttggaaccct catttgacat tttatagata tgtaaattat tctggtttgt
     3061 catgggacat catttcttct cctgtaacag agcatgatag aaaaatttat gatgaatata
     3121 ggaataaatt aactaatagc gagggcctgt ataattattt tatagatcct aatactggtt
     3181 caataatagg tttgcctcac ttaattgtga cgttacaatc acagatgttt ctagccgaca
     3241 caatcaatga tagtgtttct gactttgcag gttggttagg agatttaatg acttgctggg
     3301 gtgaagttaa gaaattagga atacaaatgg agcaaggtgt atttgcatta gtaggtacgg
     3361 ctgcaggtgg aacatttagt ctagaagatt tataccaaga tgttgacgcg gtaaatgttt
     3421 ataccttagc aaaaagaaat tctgattcaa cagctttatc ggctttaaaa acgtactatt
     3481 gtgataaggg tgctattgat agatttaatc aatttgttaa gaacagattt ggttcttcag
     3541 ataaaatcgc ttcagtaaca aatagtttat tagaaaatga cgaaacagtt gatatcttag
     3601 gtgtagggat aatttcattt ttcattgata aaatagttaa taattcactt gggacagatt
     3661 ttacttatct tgattttatt ggagatgagg ggaaagttgc aaatggattt tctgaaaaaa
     3721 ttattcaatt tcaagaaaat agaagtaaac ttaattaaga atcgtttact atttaaacag
     3781 tgtccttttc ctttttaaat atatacgata aaataagtat atgaattgta aaaggacatg
     3841 atgattatgg aagaaataga atggaataat ctgactcaaa ataataaaaa taattctgga
     3901 tgtggaatta tctttatgtt tgttatagtt ttgggaatag tagtactttt aataactgtc
     3961 aagatagtag attactttgc gaatactcct gaagaacaaa tacagagaaa acttcctgag
     4021 tttgaaagag taccacctta tgatccaaga gataattcat ttcaagtaaa aaaattaaaa
     4081 gagtctccaa atgaaatgtg gtttgaagtt acagttgaat caagcgactt caaagaaaaa
     4141 aagaaagaat acaattatat tgtaaaggca aaagtatcaa aaagatttat ttttaaccct
     4201 aaattagaaa tatatagtgt tgtaatagaa taatagtgtt aaaaaaattg taaaagttaa
     4261 agaagtcaaa ttctgatgtg aaaaataaaa tataccatgg aagacataaa agaaaaactg
     4321 gataactagt ttatttaatg gcagaccgtt aaggcctgcc atttttatgt attttagcgg
     4381 aataaatata atcatgcggg agtgtaaact tactgtttca aaaagtatac tttttgacat
     4441 gccttgattt tctttgttta tgtatggcat aataaccaca taatacaatt tgaaacgttt
     4501 ctgatttaat ctgattgttt tgaaacaatt ttagtgaaaa aagggtagat aaaaacgatg
     4561 agaaaatttt tttatatccg ggtcagtagt tatgatcaat cgatcgaacg acaactgatt
     4621 tccgcgaagg aattaggaat ccctgaagaa tatatatttg tagaaaaagc cagcggcaaa
     4681 gattttaaac gccctgaata tcaattaatg aaacggatgt ttcgaaaagg agatttactc
     4741 tatctacaat cattagatag actaggcaga aataaacaaa tgattttaga agaatggcga
     4801 gaattaacta aggaaaagca gattgatatt tctgtgttag acatgcctct gttagatact
     4861 gctagttaca agcaactaga tgggttagag acgcttatct ctgacttaat tctgcaatta
     4921 ctcagctata tggccgaaga cgagcggaaa cgaattaata gccggcaaag agaaggcgta
     4981 gaagctgcga aacaaaaggg tgtaaaattc ggcagaaaga aaattgcttt acctcctgaa
     5041 tttcctgcga tctattctga ctggaaagca ggaaagataa ctgcagtcta tgctatggat
     5101 caattgggca tgaaacgaaa taccttttat cgacgggtga aagaatatga acataccttg
     5161 caccactttt cttgatagat ataacagcta ttagacggga agggagagtt tgaaaatgga
     5221 cttaacgaat caaagggtcg tttttactgg aacgctgcag caaatgacac gaacccaagc
     5281 catcggtttg gttcactctt taaacggcca ttgtcaatca agtgttactt caaaaacaaa
     5341 tttcctggtt tgtggtcagt attctaagtc gttgtttgat gattctctct atacaaaaaa
     5401 ggaacaaacc gcgcgggact tgattgcgtt aggtcatgag attaccattt tatcagaagt
     5461 cgaattttat gcgttaatta gtcaacagtt gaaagaatgg caacggtatt tataatcgtt
     5521 agtaaaattt acaaggagga aaatttttat gaagcgaaaa tcttatgatc gttggggcat
     5581 tgaaataact agttttaatc gaaatattgc ttttcacgtg gagtgtgact gtggggaatt
     5641 agcaaaaagt gtttatcaaa aaaattactt ttactgtcct aaatgccatc gccgatacgg
     5701 ggtacatgga acatagaaac gaaatagtgc ggtagaaaag cgaatgaatg tagtatattt
     5761 ctacaaatca ttcgctttct ttattttata aatagttggt cgagagatcc cgttttcttt
     5821 tgcaatctct gcaactggaa tgccttgctt taacatgtcc accacggttt taaaaactaa
     5881 gcgtttttgc ggatctgttg agttaataga atactcgatt ggtcgtccct tatatcggcc
     5941 ggctttttga gccaataata ctccttgccg ctgacgttca cgaattttct cacgctcgtt
     6001 ttgtgcaata taacttagca gtgataaaaa catatcgaac atagcggtat ccaggagttc
     6061 atttccagta ttaaaatcta aaaactgtgc atctaatatt tttaacgcta cttttttctg
     6121 tttcataaaa gcaactgtat tttttatatc ttcataatct cttcctaaac gatctagtga
     6181 tgtaacgatg acgcaatcac cttcacggat ataatttagt aatttttgaa actcaggacg
     6241 ctcagtatct ttaccactgg ctttttcttg gaataattta tcaatgttaa gtccttccat
     6301 cattgccaat tgtcgatcca aattttgatc ttgtgaagat actcgaatat agccaatttt
     6361 tcccataaaa aactcctttt taaaagtgat ataatttaca tgtaaaattt acttgtagtt
     6421 ttactgctat catagcattt ttaaaaataa attttatgta gacttaaaat ttacttcatg
     6481 gagggtttaa atggatgaaa tcaaaagtaa caaaaaagca tttggcattt atttaggaga
     6541 acctagtaca gaacaattaa accaatttt
//
LOCUS       DAZKKZ010000105         6432 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.108, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000105 DAZKKZ010000000
VERSION     DAZKKZ010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6432)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6432)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6432
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.108"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..1173
                     /locus_tag="ACG8LA_002718"
     CDS             <1..1173
                     /locus_tag="ACG8LA_002718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HFQ0204971.1"
                     /translation="KQYVKRRAKRRLFLWVFGTSAGLITILITVFVTLFLILAAGSID
                     NSDSSSGGEAFTGEYSEGLPIYKEIKGRGPFSDEIAQYAVGAAVKYKLLPSVILSQYG
                     YESAFGTSASARNDLNYFGITWFDGCLFPKGTARGIGGIEGGWYMKFPNSKAAFSYYG
                     FMVATQSNFNACVGNKSPGASLLILGRGGYAAAGITEDSAYYKNCMSIINTNKLMEYD
                     EFAIKHWREGGGTGGTITGSWGNPFPGSSLDKNSFSGGQLFGKNPGGEFRPNGFHDGL
                     DFGSVDHPGSEIHAVHGGKVVYVGNPGISGLGACVIVINYDGLNMVYQEFANSTGNSR
                     VKVGDQVKVGQVIGIRDTAHLHLGFTRMDWRQAQGHAFIDDGTWIDPLPFLNSSKK"
     gene            1189..1833
                     /locus_tag="ACG8LA_002719"
     CDS             1189..1833
                     /locus_tag="ACG8LA_002719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204972.1"
                     /translation="MENKTLKIVLTAAISVSLIGNIALFWQLKEEQETNTYKIEEVAK
                     NASDKLKKNSSEAQAKIDKLNQTINEKNQEIDQLKQQDGTKAKEEVTEAQRKTAEEFG
                     QLAIDKSLSRNELTEKLKDVATQEVIDKLSPADDDHQHDDYGSYSFTLGDVQTYAQTS
                     SVKEEQNFVVFVDYTIGNPQFKDVKPQKIKGGLTVTEKQVDGQWKVTDFSYFTR"
     gene            1844..2650
                     /locus_tag="ACG8LA_002720"
     CDS             1844..2650
                     /locus_tag="ACG8LA_002720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204973.1"
                     /translation="MSKKKGARQRFKKRKSYLRWLGIFMILGFLILASPIYTHKKVDI
                     PDEVSTNAFLNTKELTMVSKEKGANQQLVFEFAIDDEDQSLLKELANLNYRVEVKTAK
                     GDYQAIKAKVIKVSDDYFVVKLAHVPEEYIAMRLTIIPEKIDPKVDMQEPQDLIYYVH
                     EDKVKDQVKDEDYEQHAINYKVKGYKKEQKAAQKQMESFQATIDLNEELVKKLKDQLP
                     YQVADDQENTENKINSYQQEIETSKTQMKDQEEIIQKLQEKIDRMTKEKI"
     gene            2672..2902
                     /locus_tag="ACG8LA_002721"
     CDS             2672..2902
                     /locus_tag="ACG8LA_002721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204974.1"
                     /translation="MKRTNLADKDTFAEQKVLIKAYLKVVKAKEICREVNLSNTTISE
                     LKNGRKNLDTLKFRSFEALYVAAKKYFTADNK"
     gene            3416..3724
                     /locus_tag="ACG8LA_002722"
     CDS             3416..3724
                     /locus_tag="ACG8LA_002722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204975.1"
                     /translation="MEVRIRNVDEKIVREIDRRCDELSNRTGNKWSRNDYLKLLVEND
                     FDRPLMEYKQDKFDQLLNQLIDKFSFVQSHNTKVLEEYICQNNQIIELLIEQSRGGEV
                     "
     gene            3726..4148
                     /locus_tag="ACG8LA_002723"
     CDS             3726..4148
                     /locus_tag="ACG8LA_002723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204976.1"
                     /translation="MAKVIDKHIYFYETHIDVLDEIIATHAEVKNYSEAVRFLCMNYD
                     SEVEKKVNSNQAKLNAMGKEISILTEMVSEFADLHLKDTGILIGTNSTVYQEAKERVE
                     GKIKANQTKKYSPKIKKTISESVTTKSEVFDPTRFLKR"
     gene            4168..5757
                     /gene="mobP2"
                     /locus_tag="ACG8LA_002724"
     CDS             4168..5757
                     /gene="mobP2"
                     /locus_tag="ACG8LA_002724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobP2 family relaxase"
                     /protein_id="HFQ0204977.1"
                     /translation="MSKSPAVILTCQFTLPNKKSFSTYIDYMTREKALEEKERRTPEE
                     EQELRLIKNALEDFYIPEGETFSESKTGKEFSETSNEAQSLMKHGINFDKLEEQDFTK
                     YLSYMTRHYALEQKKVLTHSEQKEYQRLNQAIKKYQTEPHKKASGNLPGVFSMASDEV
                     KGSDLKEIKQTFQRGQQKGSIIYQDVVSHDHSYLEKIGLYDPKTDTLDEEGLKAAGRK
                     MMETLFEKEQLNETGYWMATIHRNTKHIHIHFAVVEKKNTRKPYTEIENGVSYIVPKG
                     KRRQATLDEMKTNYVHELERFSYEKNRMGMEKRNLLTRKSDLRNTLTKVVKEPVRYDR
                     HAMSLLTEVYKNLPKKRSEWHYGDENRTKLSPYTREKLDELTQYVLTKEPGYQEYIQI
                     SKALKEEAKSLYGESKRESKDAEKNALFDLKKRTGNAILTELKKQDSQIKPLIERMDQ
                     MQSIYNERSFRTLKQLPTNEYKYSYEEFMKRRKQFQQRVVTQRSLRQLNRTINAHEEK
                     YHASKAYEEQQRRIQMEQERQ"
     gene            5769..6104
                     /locus_tag="ACG8LA_002725"
     CDS             5769..6104
                     /locus_tag="ACG8LA_002725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204978.1"
                     /translation="MKQYLDQWKVIEGSLREERIEQLPDCLEKEHLFQIREMLINEQF
                     DPNQFLVVEYPATGVYCCNHVKGEKYFIIQEYEGKLAPYYTTWEMNEEGINNFPCKSI
                     EESISLTEC"
     gene            6245..>6432
                     /locus_tag="ACG8LA_002726"
     CDS             6245..>6432
                     /locus_tag="ACG8LA_002726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204979.1"
                     /translation="MAYSTIGVVVEKSRDNLVFVTEIQTGRAFVVTDKAAKAYQSGDI
                     LTLNLTTKTFVDAAEDYP"
BASE COUNT         2469 a          961 c         1334 g         1668 t
ORIGIN      
        1 aaacagtatg ttaagcgtcg tgcaaagcgg cgcttatttt tgtgggtgtt tggtacttct
       61 gcaggtttga ttactatatt gatcactgtg tttgtgaccc tttttctaat acttgcggca
      121 ggttctattg ataattctga ttcaagtagt ggtggcgaag cttttacagg agaatattcg
      181 gaaggcttac ccatttataa agaaatcaaa ggaagaggcc ctttttctga tgagattgcg
      241 caatatgctg taggtgcagc agtgaagtat aaattattac caagtgtgat cctttcgcaa
      301 tacggttatg aatcagcgtt tggtacgtcg gcgtccgcaa gaaatgatct caattatttt
      361 gggattacgt ggtttgatgg gtgtctgttt cctaaaggaa ctgcgcgtgg aattggtggc
      421 attgaaggtg gctggtacat gaagtttccc aactcaaaag ctgccttctc ctattacggc
      481 tttatggtag ccacacaatc aaattttaat gcttgtgtcg gaaataaaag ccctggcgca
      541 agcttattga tcttaggacg aggagggtat gccgccgcag gaattactga agacagtgcc
      601 tattataaaa attgtatgtc tattattaat acaaataaat tgatggagta cgatgagttt
      661 gcgattaaac actggagaga aggcggcgga actggtggta cgattacagg aagctggggc
      721 aatccattcc caggaagtag cttagataaa aattcgttca gtggaggaca actttttggg
      781 aaaaatccag gaggagaatt ccgacctaac gggttccatg atggactaga ctttggttca
      841 gtcgatcatc caggaagtga gattcatgcg gttcatggcg gaaaagtcgt gtacgttggc
      901 aatcctggta tttcaggttt gggtgcgtgt gtgatcgtga ttaattacga tggcttgaat
      961 atggtgtatc aagaatttgc aaatagtaca ggaaattctc gagtgaaagt aggcgatcaa
     1021 gtgaaagttg gtcaagtaat tgggatacga gatacagcac acttgcattt aggatttact
     1081 cgaatggatt ggcgtcaagc acaaggacat gcattcattg atgatggtac atggatcgat
     1141 ccgttaccat ttttgaatag cagcaaaaaa tagatcagga gaaaaaatat ggaaaataaa
     1201 accttaaaaa tcgtcttaac agctgcaatt agcgttagtt taatcggcaa tattgcgttg
     1261 ttttggcagc ttaaagaaga acaagagaca aatacctata aaattgaaga agtggctaaa
     1321 aacgcgtctg ataagctcaa aaaaaattct tctgaggcac aggcgaagat cgacaagtta
     1381 aatcaaacca tcaatgagaa aaaccaagaa atcgatcagc tgaagcaaca agatggcaca
     1441 aaagcaaaag aggaagtaac tgaagcacaa agaaagacgg cagaagagtt cggtcaattg
     1501 gccattgata aatcattaag cagaaatgaa ttaacggaaa aactaaaaga tgtcgcaacc
     1561 caagaagtga tcgacaaatt aagtcctgca gacgatgatc accaacatga cgactacgga
     1621 agttactctt ttacattagg tgacgtgcaa acttacgctc aaacaagcag tgtaaaagag
     1681 gaacaaaatt ttgtcgtatt tgttgattat acaatcggca atcctcaatt taaagatgtc
     1741 aaaccacaaa aaataaaagg tggattaact gtcactgaaa aacaagtaga tggtcaatgg
     1801 aaagtcacag actttagtta tttcactcgt taggaggaag aaaatgagta agaaaaaagg
     1861 agcaagacaa cgttttaaaa aacgaaaaag ttatcttaga tggctgggga tctttatgat
     1921 tctcggcttt ttgattcttg ctagtccgat ttacacacat aaaaaggtag acataccaga
     1981 tgaagtaagc acgaacgcat ttttaaacac gaaggaactg acgatggttt caaaagaaaa
     2041 aggagcgaac cagcaattag tttttgaatt tgcgatcgac gatgaagatc agagcttatt
     2101 aaaagaacta gctaatctta attatcgtgt agaagtaaag acagctaaag gggattatca
     2161 agcaataaaa gccaaagtga tcaaggtgtc tgatgattat tttgtagtga agttagcaca
     2221 tgtaccagaa gaatatatcg ccatgcgttt aaccattatt cctgaaaaaa ttgatccaaa
     2281 agtggatatg caagaaccac aagatctgat ttattacgtt cacgaagata aggttaaaga
     2341 tcaagtgaaa gatgaagatt atgaacaaca tgcgatcaat tacaaagtga aaggatacaa
     2401 aaaagaacaa aaagcagcac aaaaacaaat ggaatccttc caagcaacca ttgatttgaa
     2461 tgaagaatta gtgaagaagc taaaagatca attgccttat caagtcgcag atgatcagga
     2521 aaatactgag aacaagatta atagctacca gcaagaaatt gaaacatcga aaacgcaaat
     2581 gaaagatcaa gaagagatca ttcaaaaact tcaagaaaaa attgatcgta tgacaaaaga
     2641 aaagatttag aaggacaggt ggagtgaaaa aatgaagcga acaaacttgg ctgacaaaga
     2701 tactttcgct gagcagaaag tattgattaa agcctatctc aaagttgtaa aagctaaaga
     2761 aatatgtcga gaagtgaatt tatctaatac aacaatatct gagttgaaga atggtcgaaa
     2821 gaatttagat actttaaaat tcagatcatt tgaagctcta tatgtagctg ctaaaaaata
     2881 ttttacagct gataacaaat aaaaaacagg agtattttat gtgaaaaaag tatataaaaa
     2941 atgcttatga atcagctata tcaccttaac catttgttaa tgagatggga gaaaacatta
     3001 accacgattc taacgcaaac atcaagcaca taaaacattt aacactcctc ctttctggct
     3061 gaagatttca accaaacagg aagacagcgt atcaattata gcatacactt tttcttaaat
     3121 tcatttttca tatgacaaaa tatttccttc taatcgacaa agttagaagg attttttatt
     3181 gtctaaatac acaaataacc ttaatttata aagagcataa ggaaacgtgg gaacactttt
     3241 taaaaaaagt gttccaatag gctgtgccta ttacgtttct caaaaataat tgtgggaaca
     3301 aaatatttaa aaataggata gtgaaaggat agcaaaggat agtaaaagga tagaagcagg
     3361 atagcgaaaa ggataggctc cttttcgcta tcctttttaa attggaggaa ttaatatgga
     3421 agtaagaata agaaatgtag atgagaaaat cgtaagagaa attgatcgaa gatgtgacga
     3481 actaagtaac cgaacgggta ataaatggag tcgtaacgat tatttaaagc tactcgttga
     3541 aaatgatttt gatcgtcctt tgatggaata taaacaagat aaatttgatc aattattaaa
     3601 tcagttaata gataaatttt cttttgttca aagtcataat acaaaagtat tagaagaata
     3661 tatttgtcag aataatcaaa ttatcgaact tttaattgaa caaagtagag gaggagaagt
     3721 ttaacatggc caaagttata gacaagcata tttattttta tgaaacacat atagatgttc
     3781 tagatgaaat tattgcaact catgcagagg ttaaaaacta tagtgaagcc gttcggtttc
     3841 tatgtatgaa ttatgattca gaagtggaga aaaaagtaaa ttccaatcaa gcaaagttga
     3901 atgcaatggg aaaagaaatt tctattttaa ccgaaatggt ttcagagttt gcggatctcc
     3961 atttgaaaga tacagggatt ttaattggta caaattcaac tgtttaccaa gaagcaaaag
     4021 agcgtgtgga aggcaagata aaagcaaatc aaacgaagaa atattctcct aagataaaga
     4081 aaacaataag cgaatcagtg actacaaaaa gtgaagtatt tgatccaaca aggttcttaa
     4141 aacgataaaa attagaagga gaatgtgatg agtaaatcac ctgcagtcat tctcacttgt
     4201 caatttacct tgcccaataa aaaatctttt tcaacataca ttgattatat gacaagagaa
     4261 aaagcgctgg aagaaaagga acgacgtacg cccgaggaag aacaggaact gcgtctaatc
     4321 aagaatgctt tagaggattt ttatattcct gaaggagaaa ctttttcgga gagtaagacg
     4381 ggtaaagaat tcagcgaaac gtcgaatgaa gcgcaatcgt tgatgaaaca tggaatcaat
     4441 tttgacaagt tagaagaaca agattttacc aaatatcttt cttatatgac acgtcactat
     4501 gcgttagaac aaaagaaagt actgacgcat agtgaacaaa aagaatacca acgcttgaac
     4561 caagcaataa aaaaatatca aacagagcca cacaaaaaag cttcaggaaa tcttcctgga
     4621 gttttttcta tggcttcaga cgaagtgaaa ggaagtgatc tgaaggagat caagcaaacc
     4681 ttccaaagag gacaacaaaa aggctcaatc atttatcaag atgttgtctc tcatgatcat
     4741 tcgtatcttg aaaaaatagg attgtacgat cccaaaacag atactttaga tgaagaaggt
     4801 ttaaaagcag ctggaagaaa aatgatggag acattgttcg agaaagagca actgaatgaa
     4861 acaggctact ggatggcaac gattcaccga aataccaaac atatccatat tcattttgca
     4921 gttgttgaaa aaaaaaatac gcgtaaacca tacactgaga ttgaaaatgg tgtgagttat
     4981 atcgtaccga aagggaagag aaggcaagca acattagacg aaatgaagac taattatgta
     5041 catgagttag aacgtttttc ttatgaaaaa aatcgaatgg gtatggagaa acgaaattta
     5101 ttgacacgga aaagtgattt gcgtaacacc ttaaccaaag tagtgaaaga gccagtacgt
     5161 tatgatcgac acgcaatgag cttattaact gaagtatata aaaacttacc taaaaagcgt
     5221 tcggaatggc attacgggga tgaaaatcga accaaacttt caccatacac aagagagaaa
     5281 ctcgatgagt taacccaata tgtgttaaca aaagaacctg gatatcaaga atatatacag
     5341 atttcaaaag cattgaaaga agaagcaaaa agtctttatg gggaaagcaa gagagaatca
     5401 aaggatgcag aaaaaaatgc tctctttgat ttaaaaaagc gcacaggaaa tgccattcta
     5461 acagaactga agaaacagga tagtcaaata aaacctttaa tagaaaggat ggatcagatg
     5521 caatctattt acaatgaacg atcctttcga acacttaaac agttgccaac gaatgaatac
     5581 aaatatagtt acgaagaatt catgaagcgc aggaaacaat tccaacaaag agttgtcacg
     5641 caacggagtt tgcgtcaatt aaatcgaacg attaatgccc atgaagaaaa ataccacgca
     5701 agtaaagcat acgaagagca acaacgaaga attcaaatgg aacaagaaag acagtaggag
     5761 gaatagcaat gaaacaatat ttagatcaat ggaaagttat agaaggatca ttaagagaag
     5821 aacgaatcga acaacttccc gattgtttag aaaaagagca tttgtttcag ataagagaaa
     5881 tgttgataaa cgaacagttt gatccaaatc aatttttagt cgttgagtac ccagctactg
     5941 gtgtgtactg ttgtaatcat gtgaagggtg aaaaatattt tatcattcaa gaatatgagg
     6001 gcaagttagc gccttattat actacttggg aaatgaatga agaggggatc aataacttcc
     6061 cgtgtaaaag cattgaagag tctatttcac tcacagaatg ttagttgtta agtgaataaa
     6121 agaagtaaaa gagtcctgaa cgtgattgtc caggactctt ttttttcact gaattgtttt
     6181 ccgccaattc attgagtggt gcgatttccg tctacattat atcaaaagaa aggaggaaga
     6241 agaaatggct tattcaacga ttggagttgt tgttgaaaaa agcagagaca atcttgtttt
     6301 tgtgacagaa attcaaacag gcagagcttt tgtagtcaca gacaaagcgg caaaagcata
     6361 tcaaagtggc gatattttaa cgttaaatct gactacgaag acgttcgtcg atgcggcaga
     6421 agattatcca tt
//
LOCUS       DAZKKZ010000106         6387 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.109, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000106 DAZKKZ010000000
VERSION     DAZKKZ010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6387)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6387)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6387
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.109"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            330..1175
                     /locus_tag="ACG8LA_002727"
     CDS             330..1175
                     /locus_tag="ACG8LA_002727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFQ0204980.1"
                     /translation="MDEMKLIGIDLDGTLLNSDQSISQKNARTMKHLPEDCFPFICSG
                     REVEDINNILKKSGLRIPAVGLNGSVGFDGEKKIFESSFDKNDVKKIDSVLSKFPTKI
                     YTNLGSYESQNYKNKMKKIFHEVGSEFSIKELNYELEYEKSICSIPYNNIEEIIEKDA
                     ISIYKFFIFIPNRQLKANIFNHLKKMLNVSVTESAPVNIEIVPQNVSKGVVFDRLESI
                     YNLKKPLRIAIGDSLNDLSMFESADISFAMGNSHQEIMKKADYVTVSNDKDGVSQAFE
                     RILTI"
     gene            1456..2676
                     /locus_tag="ACG8LA_002728"
     CDS             1456..2676
                     /locus_tag="ACG8LA_002728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HFQ0204981.1"
                     /translation="MVKFIHAADLHMDRSFEGLTTLDKTVQEKLLKTNLTVLSNIIEQ
                     AIINNVDFVLLAGDNFHQNRPSLKIQKHFSEQMKRLEKNHIPVFIIFGNHDFYQKERY
                     WFSFPKNVHLFTSETVETKKITIKSGETVSLSGFSYRQPWIQKDKVMEFPSRELTDYH
                     IGLYHGEPGVSQKGNYAPFQPSKMQEKGYDYWALGHIHVPTVLNEKQTIVYPGAPQGH
                     TKKEQASTSILLVELSKGSCQIHPIKVAEVYWKTKEISLRKARTTKEVIVHIRQQLSK
                     VEDGFSLIEIKLKDYDHLNTDVLERIQSGELLDYLLEEFSDRINDFFIWRISLIENTF
                     YTKTPLAASAKLMEQLFQYYQTPQDFQQILNEVYSHQEAARILSELPEYQEETLEKAK
                     QLLNQDFLFEEDQE"
     gene            2673..5393
                     /locus_tag="ACG8LA_002729"
     CDS             2673..5393
                     /locus_tag="ACG8LA_002729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFQ0204982.1"
                     /translation="MKILRIEIAAFGKWRQKSFDFYSGNQLIYGGNEAGKSTIYQFIQ
                     AILFGFPSKGRKKKDYTPKDGSAYGGKIWLKHPVYGEFAVERYKQQNRGKSKVWLGDQ
                     VGSDELLEKLIAPLTKELFQQVFTFQQEQLMELDHLREKELHDALISLGITGSSQVFQ
                     KRQEYYQKAQQLFKKKGQKLLINQKLNEWKELQEKIHQKQEQEAYFGKLIQQEQEYES
                     QQQQLLAQLKEANKQFSLARQQELNFSLYEEWQSLKKNSTTGLPDEQLLLDLESFSKR
                     YQQTNERLEELEATLEKHSGMDQQSARYYFYLEQEQELKDLQQLQFTAEQLNEEWQRL
                     QIETRETNSELKILEQRWHWQKNPLPEEFLYEEEWKHLLAEERRIADLESQISVRLQI
                     AKEQQEMIEAEVNDLEETYPALLQNQSEIAPVSSSKPYMLMAGGAIIIAGIFVPMPLK
                     VILLLIGAGMIGYFFYKRQPKIKTKNDFSEIKGMWQEKLGQLDLALAQLAEAEEKQKR
                     TGEEKQILQQEVYRFADHRHLGKMDTLKLMKEYGQEVIDYQKLYGVFERKHKREQEIQ
                     EKLRQIDQKFEFVKEWLPIQDKTISEKMVLLSRFIQEMEQMKFARSYQQNTLLKQEIN
                     QLKKKQKVWIQEYSEQLTQAGLSYPSEVPVFLQKAKQAEQQMKRYNELSEMLTPLFPE
                     ELTKEKLSVRLRQLKEKQSQLQQEEKEASENRQRLQLQVEELQRDGTLDELYQQASRQ
                     KAKLQELLEEWGALEIAGTFLGDLSTEMSERQLPQLLRAAGDYLGILTKGNYQKILLK
                     NDTLTLTDGYTEFPIYELSTGTKDQLIMAMRFAYLSLEANRSICPIIIDDGWLHYDHQ
                     RKYQLAELLAKFGEKYQIICFSSDKEMVSYYHEMNQIVKQLEGANNEKNS"
     gene            5377..6321
                     /locus_tag="ACG8LA_002730"
     CDS             5377..6321
                     /locus_tag="ACG8LA_002730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HFQ0204983.1"
                     /translation="MKKIRDLVIDEQFEQFVLIKSADVRIAKNGKKFIAFTFQDTSGT
                     IDGKYWDASEEEINKFTAGTVVFLNGKREVYQGNPQVKILHMRLTRVDEPGEPSLYME
                     RAPLKKEEMEEEINQLLFEITNAHWNRIVRYLLNKYQKQFFEFPAAKRNHHAFASGLA
                     YHTLTMLHLGKSIADEYPELNRALLYAGIILHDLGKVIELSGPMSTEYTLAGNLIGHL
                     VLIDEEITKACLALKISEADEDVLVLRHMVLAHHGLLEYGSPVRPRIMEAEILHQIDN
                     IDASMQMMLTSIRQTEPGKYTDRIFGMDNRSFYVPKDL"
BASE COUNT         2379 a          987 c         1231 g         1790 t
ORIGIN      
        1 aaggcaaaaa gatgaactag aaatagttca tctttttttg tttaaatctt ttgctaagtt
       61 gaactaatag agtcttttat gaatatcgaa gttagttttt cacctaactt cgttttttat
      121 agttggttat tataaaatag taatatagct gatttggatt caattcatat ttatttataa
      181 atcaaaaata cagagaatag tatataaatg tcctttccta ttcttaaaat gatgtttgta
      241 cttacttaaa ttaggtataa ttagtatatg ttttgtgaga aatttagact tacaataagc
      301 agtgaattta taatcaacgt ataggagaca tggatgaaat gaaactaatt ggtatagatt
      361 tagacggtac tcttttgaat tctgaccaga gcattagtca aaaaaatgca agaacaatga
      421 aacatttacc ggaagactgt tttccattca tttgttctgg aagagaagta gaagacatta
      481 ataatattct caaaaaatct ggtttaagga taccagcagt agggttaaat ggttctgttg
      541 gatttgatgg agaaaaaaag atatttgagt cttccttcga taaaaatgat gtaaaaaaaa
      601 ttgattctgt cctatcgaaa tttccaacca aaatatatac aaatctcgga agttatgaat
      661 ctcagaatta taaaaataaa atgaaaaaaa tttttcacga ggtagggagt gaattttcta
      721 tcaaagagct aaactatgag cttgagtatg aaaaatctat ttgttcaatc ccttataata
      781 atattgagga aattatagaa aaggatgcta tcagcattta caaatttttt atttttattc
      841 ctaatcgtca attgaaagct aatatattta accatttgaa aaagatgcta aatgtgtctg
      901 ttactgaatc ggcacctgta aatattgaaa tcgtacctca aaatgtatct aaaggtgtgg
      961 tgtttgatcg tttggaatca atctacaatt taaagaaacc tttgagaatc gcgatcggag
     1021 atagtttaaa tgacttatct atgtttgaaa gtgcagatat tagttttgca atgggaaata
     1081 gtcatcaaga aatcatgaaa aaagctgatt atgtcactgt ttcaaatgat aaagacggag
     1141 tatctcaagc atttgaaaga attcttacca tataaactaa ttaaggtagt atagaacata
     1201 gaattctaaa tacggaaaaa tggagcataa attccagtac aaatagtact tcttcagtgt
     1261 caaacgaagc gaatataaca tagatattta ggattgtgac aaaaatcatg tcacaatctt
     1321 tttttcgaat aaacttattt tttgaagtcg gccatttatc gtaatttctt tgcataatac
     1381 gaacaaattt tcggttattg atgaaaaaaa acattgaaaa tggtatgata aaagaaaaaa
     1441 aggaggaaat ttttaatggt gaaatttatc catgcggcag atttacatat ggatcggtca
     1501 tttgaaggac tgacaactct tgataaaact gtacaggaaa aactattgaa gacgaatctg
     1561 accgttttat caaatatcat tgaacaggca ataataaata acgttgattt tgttttactt
     1621 gcaggagata attttcatca aaatcgtcct tcattaaaaa tacagaaaca tttttcagaa
     1681 cagatgaaac ggttagaaaa gaaccatata cctgtattta taatattcgg aaatcatgat
     1741 ttctatcaaa aagagcggta ttggttctcc tttcctaaaa atgtccattt atttacatcc
     1801 gaaacggtag agacaaaaaa aataacgata aaaagtggag aaactgtctc tctcagtgga
     1861 tttagttatc gtcaaccgtg gattcaaaaa gacaaagtga tggaatttcc ttctagagaa
     1921 ctcacagatt accatattgg gttgtaccac ggggaacctg gcgtctctca aaaaggaaac
     1981 tatgctcctt tccaaccctc aaagatgcaa gaaaagggat acgattattg ggctttaggg
     2041 catatccatg tgccaacggt cttaaatgaa aagcaaacaa ttgtttatcc aggtgcgcct
     2101 caaggtcata ctaaaaagga acaagcttct acatctattc tactagttga attaagtaaa
     2161 ggaagttgcc aaatacatcc gattaaagta gcagaggtct attggaagac aaaggaaata
     2221 tcattgagga aagcaagaac gacaaaagag gtcattgttc acattcgtca gcagctttca
     2281 aaagtagagg atggatttag tttaattgag ataaaattaa aagattatga ccatctcaat
     2341 acagatgttt tggaacggat acaatcagga gagctattag actatttgtt agaggaattc
     2401 tcagatagga taaatgattt ctttatttgg cgtatttctc tcatagagaa tactttttat
     2461 acgaagaccc cacttgctgc ttctgctaaa ttgatggaac agttatttca atactatcag
     2521 acacctcaag atttccaaca aattttaaat gaagtatata gtcatcaaga agcggctaga
     2581 atattgagcg aactgccgga atatcaagaa gaaacacttg aaaaagccaa gcagctgctt
     2641 aatcaagatt ttttatttga ggaggatcag gaatgaagat tttaaggatc gagattgctg
     2701 cttttggaaa atggcgtcaa aaaagttttg acttttattc aggcaatcag ctgatctatg
     2761 ggggaaacga agcaggaaaa tcaacgattt atcaatttat tcaagcaata ttatttggtt
     2821 tcccttcaaa aggccgtaaa aaaaaggatt atacaccaaa agacggctca gcctatggcg
     2881 gcaaaatatg gcttaaacat cctgtatatg gtgaatttgc tgtcgagcgc tacaagcagc
     2941 aaaatcgcgg aaaatcgaag gtgtggctgg gggatcaagt gggaagtgat gagttactag
     3001 aaaaactgat cgcacctttg acgaaagagt tattccagca ggtatttact ttccagcaag
     3061 agcagttgat ggaactagat catttgagag aaaaagagct acatgatgcg ctgatttctt
     3121 taggcatcac gggcagttct caagtattcc aaaagcggca agaatattat cagaaagcac
     3181 aacaattatt caagaaaaaa ggccaaaaat tactaatcaa tcaaaaatta aatgaatgga
     3241 aagagctgca agaaaaaatt catcaaaaac aagaacagga agcttatttt ggcaagttga
     3301 tccaacaaga acaggaatac gagtcgcaac agcagcagtt attggcacaa ttaaaagagg
     3361 cgaacaaaca attttcatta gccagacagc aagaacttaa tttttcttta tatgaagaat
     3421 ggcaatctct caaaaaaaac agcactacag gtcttcctga tgagcaactt cttttagatc
     3481 tggagtcttt ctccaaacgg tatcagcaaa caaatgagcg tttggaagaa ttagaagcaa
     3541 cactggaaaa gcatagcggg atggatcagc agtcagccag atattatttt tatttagagc
     3601 aggagcagga actaaaagat ctccagcaac ttcaatttac agcggaacaa ttaaacgaag
     3661 aatggcaaag attacaaatt gagactagag aaacaaattc agaattgaag attttggaac
     3721 aaaggtggca ttggcagaaa aatccgttac cggaagaatt tttatatgaa gaagaatgga
     3781 agcatcttct ggctgaagaa agaaggattg ctgatctaga aagccagatt tctgtgcgtc
     3841 tccaaatagc taaagaacag caagagatga ttgaagcaga agtgaatgac ttggaagaga
     3901 cctatccagc attattacaa aatcagtcag agatagcacc agtctcttca tctaaaccgt
     3961 atatgctgat ggctggcgga gcaataatca ttgcaggtat atttgtacca atgcccttga
     4021 aagtgatcct tttactaatt ggtgcaggca tgattggcta tttcttctac aaaaggcaac
     4081 caaaaattaa aactaaaaat gatttctctg agataaaagg aatgtggcaa gaaaaactag
     4141 gacaacttga tctagcctta gctcaattag ctgaagcaga agaaaaacaa aagagaactg
     4201 gagaagaaaa acagattctt cagcaagaag tatatcgttt tgcggatcat cggcacttag
     4261 gaaagatgga tacgctcaaa ctcatgaaag aatatggaca ggaagtcata gattatcaga
     4321 aattatatgg cgtatttgag cggaaacata aaagagaaca ggaaatacaa gaaaaactac
     4381 gacaaatcga ccaaaaattt gagtttgtta aagaatggtt accgatacaa gataagacaa
     4441 tttcagaaaa aatggtattg ctttcccgtt ttatacaaga gatggaacag atgaaatttg
     4501 ccagaagcta tcagcaaaat actttattga agcaagaaat caatcaattg aaaaagaaac
     4561 aaaaagtatg gatacaagaa tacagcgaac aattgactca agcaggctta tcttatcctt
     4621 cggaagtacc tgtcttttta caaaaagcca aacaagccga acagcagatg aaaagataca
     4681 atgaattatc ggaaatgctt actccactat ttcctgaaga gctgacaaaa gagaaattat
     4741 ctgtaagact gcgccaactg aaagaaaagc aatcccaact ccagcaagaa gaaaaagaag
     4801 caagtgaaaa tcggcaacga ctccaacttc aagtagaaga gttgcaaaga gacggcacat
     4861 tggacgaact ttatcaacaa gctagccggc aaaaagcaaa attacaggaa ttactggagg
     4921 aatggggagc acttgaaatc gccgggacat tcttaggtga tctttcaaca gagatgagtg
     4981 aaagacaatt accccagttg ttaagagcag caggtgatta tttaggtatt ttaacaaaag
     5041 gaaattatca gaagatatta ctgaaaaatg atacactgac tttaacagac ggatatacag
     5101 aatttcccat ctatgagtta tctacaggta cgaaagatca gctgattatg gcgatgagat
     5161 ttgcttacct ctcattagaa gctaaccgtt cgatatgccc gatcatcatt gatgatggct
     5221 ggcttcatta tgatcatcag cgaaagtatc aattagctga acttttagct aaatttggag
     5281 aaaagtatca aataatttgt ttttcttctg ataaagaaat ggtaagctat taccatgaga
     5341 tgaaccaaat cgtaaaacaa ttagaaggag caaataatga aaaaaattcg tgatttagta
     5401 atcgatgagc agtttgaaca atttgtcctg atcaaaagtg cagatgtaag aatcgctaaa
     5461 aacggaaaaa aatttattgc ttttactttc caagatactt caggtactat cgatggtaaa
     5521 tactgggatg cttcggagga ggaaatcaat aaatttacag ccggcacagt cgtttttcta
     5581 aacggtaaaa gagaggttta tcaaggaaac cctcaagtaa agattcttca tatgcgctta
     5641 acaagggtag atgagccagg agagcctagt ttatacatgg aaagagcccc tttgaagaaa
     5701 gaagaaatgg aagaagaaat caatcaattg ttgtttgaga tcaccaatgc gcattggaat
     5761 cgtattgttc gctatctact taataaatat caaaaacaat tttttgagtt tccggcagca
     5821 aaaagaaacc atcatgcatt tgccagtgga ttagcttatc atactttgac aatgcttcac
     5881 ttagggaaat caatcgccga tgaatatcct gagctgaatc gagcattgtt gtatgctggt
     5941 atcattttgc atgatttagg aaaggtgatt gaactttccg gtcctatgtc gacagaatat
     6001 acgcttgcag gaaatttgat cggtcatctg gtattgattg acgaagaaat aactaaagcc
     6061 tgtcttgcgt tgaaaatcag cgaagctgac gaagatgttc tcgtattacg tcatatggtt
     6121 ttagcacacc atggcttatt agaatatggc tcacctgtac gtccaagaat aatggaagca
     6181 gaaatattac atcaaatcga caatatcgat gcttcgatgc agatgatgtt gacttcgatt
     6241 cgtcaaacag aaccaggaaa atacaccgat cggattttcg gtatggacaa ccgaagtttc
     6301 tatgtaccaa aagatttata gcaaaaattt atttttttca ttcaaaacaa aaaaagcgag
     6361 acataagtct tcgctttttt tgttttc
//
LOCUS       DAZKKZ010000107         6174 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.111, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000107 DAZKKZ010000000
VERSION     DAZKKZ010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6174)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6174)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6174
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.111"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            725..811
                     /locus_tag="ACG8LA_002731"
     CDS             725..811
                     /locus_tag="ACG8LA_002731"
                     /inference="COORDINATES: protein motif:HMM:NF033608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HFQ0204984.1"
                     /translation="MFELFICPLLIEVCVSLFSYWLNNRNKK"
     gene            complement(932..1621)
                     /locus_tag="ACG8LA_002732"
     CDS             complement(932..1621)
                     /locus_tag="ACG8LA_002732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204985.1"
                     /translation="MAFYLPYLLIFASILGIIWLSYKAYQTRYSLKGSKIRFKRFLLP
                     GVIFTLSIVLSGLFGVLEGNKRISRSILLGDITQKYEAACDKKKKEQVLTQKMEEFTT
                     CYEEMNDIFVNQEKRLTDKNMEKLTRLYQNLPEKQQKEVQDNYERTKKDVQYFKDTQT
                     EEACYNLFSDTIPFSTSEQERKERQQSVTYERYKALLQQATNIQNPTKKETALNYLKS
                     VKEWLDQQQQN"
     gene            complement(1628..1906)
                     /locus_tag="ACG8LA_002733"
     CDS             complement(1628..1906)
                     /locus_tag="ACG8LA_002733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204986.1"
                     /translation="MKEEQTTNKNYRSKTLQDIENEIKKQRAFLAPYTKERIQTTIDS
                     QVKKFHHALLNQRNKEQKKVIMQRSMDILAPLCCLIMTLLAFWLVWGE"
     gene            complement(1866..2780)
                     /locus_tag="ACG8LA_002734"
     CDS             complement(1866..2780)
                     /locus_tag="ACG8LA_002734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HFQ0204987.1"
                     /translation="MATVKVSRTTSCSRAINYAEPRATVKTGINCDIDYAKSEMKQIR
                     MLYGKDDRVQAHLLIQSFRPGEITAEKANQLGAEYAKKIAPDHQIAIYTHTDKDHIHN
                     HIVINSVNLETGNKFQAHGQAFLNKCYDLNDEICLEHDLTITERGKKPEKRTMSEIKL
                     KEKNEPVWKDEIRFAIDQTMKNKKTRTYNQFCDSLKTFGIHCLNRGKNFTYELIHKKK
                     KVRSNKLGKDYEKETILHELDRRERAYNQQRTNELRRARASIRETAKEVRREQRTLTT
                     EQPEIRPTRRNHDQHVERGADYQQELSF"
     gene            complement(2762..3142)
                     /locus_tag="ACG8LA_002735"
     CDS             complement(2762..3142)
                     /locus_tag="ACG8LA_002735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HFQ0204988.1"
                     /translation="MSEQNQYLASNHSKKYTYRSEPKQISFRVSESEFAKLKQSAEAL
                     QMSVPAFVKAKAQNARLVTPKVAPDIAQAIARDLAKAGGNINQIAKWCNTHQHDVDPG
                     DAQRLSENLKIMQKELQKIWQQLK"
     gene            complement(3593..3880)
                     /locus_tag="ACG8LA_002736"
     CDS             complement(3593..3880)
                     /locus_tag="ACG8LA_002736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HFQ0204989.1"
                     /translation="MDFTKEEKLLNAISKVYNEATIDDYPDLKEKLFLYSKEISEGKS
                     VGEVSMKLSSFLGRYILKHKFGLPKSLIELQEIVSKESQVYRGWASIGIWS"
     gene            complement(3900..4124)
                     /locus_tag="ACG8LA_002737"
     CDS             complement(3900..4124)
                     /locus_tag="ACG8LA_002737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II bacteriocin"
                     /protein_id="HFQ0204990.1"
                     /translation="MKKKVLKHCVILGILGTCLAGIGTGIKVDAATYYGNGLYCNKEK
                     CWVDWNQAKGEIGKIIVNGWVNHGPWAPRR"
     gene            complement(4579..4749)
                     /locus_tag="ACG8LA_002738"
     CDS             complement(4579..4749)
                     /locus_tag="ACG8LA_002738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204991.1"
                     /translation="MTKKHLLFGSILLGILSFSPMLLSVANKGNKKGELKLNPNYYNS
                     QNEEVFVEKLDK"
     gene            complement(4764..5297)
                     /locus_tag="ACG8LA_002739"
     CDS             complement(4764..5297)
                     /locus_tag="ACG8LA_002739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HFQ0204992.1"
                     /translation="MQPQETFTIKELSDLFKMSRQAISKHIQKLDSSMIAKNERGYKV
                     VLRSGVLQLARNLDNQRLLDKLHKHEQNNDKNAYIPNKNVVANKLLDQLREENEFLRE
                     QLALKEQNNSHIQKLLDQQQQLTLQANQQIEKLQEQLQLTYTEESSENSSTTLSEATE
                     TMDEQTKNWKKWWQLWK"
     gene            complement(5318..>6174)
                     /locus_tag="ACG8LA_002740"
     CDS             complement(5318..>6174)
                     /locus_tag="ACG8LA_002740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /protein_id="HFQ0204993.1"
                     /translation="IVSRMREKGDKTVRFTFDQLKDLSNYKATANVRFVEDLKATYEK
                     ILSLRFGRRSESGLSYDMFVMFTEFKINGDVENPYVDIRIYEKALPLLNNLDEWVRYS
                     LQQFNELQSGYAKTMFRLLKQYRTKGFAYFSKEDFLELLDIPKSYKQPDIDKRVIKPI
                     RQELTAIFKGLTIKKKYGKGRGKPVIGYQFTFKPEIKKADDFNKHAPTKEDQNKALAL
                     ADKQKEYEEPATTINEKIKQKKRELELLQQIKQLEKEKKALEKQTESALSEKEKKSLL
                     SDLDNLFQ"
BASE COUNT         1631 a         1155 c         1039 g         2349 t
ORIGIN      
        1 aaaaaaacaa attcatttca accggtgtaa attttcttaa aggaattgta tttaattcat
       61 ggtggtattt tacaatctca ttagccatat aatcacctca atccaattat gaatgacatt
      121 ttttaaatgt caagacattc atatttgacg ttcaaacaga caaaatgtcc ttcataaaca
      181 gacaaaatgt ccttcataaa cagacaaaat gtccttcata aacagacaaa atgtccttca
      241 taacattctg tatccattgg tagagtaagg acacagctta cggtaaagag gtttaaaaag
      301 aggtttaaaa agagatataa aaagaggggg gctaattttc ccgcctaaaa accacttctt
      361 ttttctttaa acaggttcgc gcatttttca aaactgccaa tccaaaacct tgcttcctac
      421 ggtcgccaaa aaggtgtgat cgctacgctc tcacattgta ctgcgcagtc gcctaaaggc
      481 tcctttgcta aaaacatgtt ggtaaagagg cctttgagcg gttctgaatg cttatctaag
      541 ccgttttaag acagtcttgg ataaaaatcc ttatctagct ttaaagcgcc ttacaggcgg
      601 tcagggcaag ccctaacaac cctaaaataa gcgatactta aaaacaccac acaagtttaa
      661 ttttttaaga tataataact tgtcgcctat ccgacagtct tgcgactgga aggaggtgta
      721 tctaatgttt gaattgttca tttgccccct tcttatagaa gtttgtgtct ctttattcag
      781 ttattggttg aataaccgaa acaagaagta aaatcaataa aggcgacatc aacctgaaaa
      841 aaagccccag agaatccaac ctctctgggg ctttcgtgta tctaatgttt gatcatttgc
      901 atgtttagtt taacatgatt gccgatcaaa ttcaattttg ctgttgctga tctaaccatt
      961 ccttgacact ttttagataa tttaatgccg tttctttttt cgttggattt tgtatgttcg
     1021 ttgcttgctg aagcagtgct ttataacgtt cgtaggtaac tgattgttgc cgttcttttc
     1081 gttcctgttc actagttgaa aaagggattg tatcactgaa taaattataa caagcttctt
     1141 ctgtctgcgt atctttaaaa tattgcacgt cttttttggt tcgctcatag ttgtcttgaa
     1201 cctctttttg ctgtttttct ggcaagtttt gataaagacg agtgagtttt tccatgtttt
     1261 tatccgtcaa acgtttttct tgattcacaa aaatatcgtt catttcctca taacaagtgg
     1321 taaactcttc cattttttgt gttaacactt gctccttttt ctttttatca catgctgctt
     1381 catacttttg agtgatatcc cctaataaaa tacttcttga aatacgttta tttccctcta
     1441 aaacgccgaa taaaccactt aaaacgattg ataatgtaaa tataacccct ggcaataaaa
     1501 acctcttaaa tcgaatttta gagcctttta atgaatatct tgtttgataa gccttatagc
     1561 taagccaaat aattcctaaa atactggcaa aaatgagtag atagggtaaa tagaatgcca
     1621 tttctattta ttctccccat accagccaaa aggctaacag tgtcatgatt aagcaacata
     1681 agggggcaag aatatccatt gatcgctgca taattacttt tttctgttct ttatttcgct
     1741 ggtttaatag cgcatggtgg aattttttga cttgtgaatc aattgtagtt tgtattcttt
     1801 ctttggtata aggtgcaaga aaagcacgtt gtttctttat ttcattttct atgtcttgta
     1861 acgttttaga acgataattc ttgttggtag tctgctcctc tttcaacgtg ttggtcatgg
     1921 tttcttcgag tcggtctaat ttccggttgt tcagtcgtaa gagttcgttg ttctcttcgt
     1981 acttcttttg cagtttcgcg aatgctagct cgagctcttc gtagctcgtt ggttcgttgt
     2041 tgattgtagg ctcgttctcg tctgtccagc tcatgtaaaa tcgtctcctt ttcgtaatcc
     2101 tttcctagtt tgttggatcg tacttttttc tttttgtgga tcaattcgta agtaaaattt
     2161 ttcccacgat tcaagcaatg aatgccgaat gttttaagag aatcacaaaa ttggttatac
     2221 gttcgagttt ttttgttttt cattgtttga tcaatcgcaa accgaatttc gtctttccaa
     2281 acaggttcat ttttttcttt taatttgatt tcagacatgg ttcgtttttc gggtttcttc
     2341 cctcgttcag tgattgttaa gtcatgttca agacaaatct cgtcatttag gtcataacat
     2401 ttgtttaaaa atgcttgacc atgggcttga aatttgttcc cagtttccag attgacggag
     2461 ttaatgacaa tgtggttatg aatatggtct ttgtctgtat gtgtgtaaat cgcgatttgg
     2521 tggtcagggg ctattttttt cgcatactct gcccctagtt gattggcttt ttcagcggta
     2581 atttctcctg gtcgaaaaga ctggatcaat aagtgtgctt gtacacgatc gtcttttcca
     2641 tacagcatgc gaatttgttt catttcgctt ttggcataat caatgtcaca gtttatccct
     2701 gttttgacgg ttgctcgtgg ttcggcgtaa ttgatcgctc ggctacaaga agtggttcgg
     2761 cttactttaa ctgttgccat atcttttgta gctccttttg catgattttt aggttttcgg
     2821 ataagcgttg ggcgtcgcca ggatcaacgt cgtgttggtg tgtgttgcac cacttggcaa
     2881 tttgattgat attcccgcca gctttggcta aatcgcgcgc gattgcctga gcaatgtctg
     2941 gcgccacttt cggtgtcacc agacgcgcgt tttgtgcctt ggctttcacg aaagccggca
     3001 cactcatttg caaagcttca gctgactgct tcagctttgc aaattcggat tcgctcactc
     3061 gaaaactgat ttgttttggc tcggatcgat aggtatattt tttagaatga ttgctagcca
     3121 aatattgatt ttgttcgctc ataagtccca ccctttcagt acgtcctacg gacgtatcgt
     3181 tcgcaatacc attgtaccta aaaaggtaca ataagtaaag ctcactaaag cttactaaag
     3241 ggcttggcaa gctctatatt tgctagccaa atacctacgt atttggtgca aataaccgct
     3301 tgtcaaaggg gcgcaagctc ccccttgaat ccccctcccc ccccactctc cacaatacaa
     3361 aaaagactag caaatgctag ccactttttg taaagtttcg cttgtttcac cttcggtgaa
     3421 attgttgcaa atcaataatt aggtagagct acattttttt cgttgttcaa agattcttat
     3481 gccatttact attaataaat ctataaatat gataattttt cggctctata atttatggga
     3541 ctgatgaatc agaattgatt cttcagtccc attttcattt tattccaaag aattaactcc
     3601 aaataccaat agaagcccat cctctatata cttgagattc cttactaaca atttcttgta
     3661 attctattaa agatttaggt aatccaaatt tatgttttaa aatatatctt ccaagaaaac
     3721 tacttaattt catactaact tcaccaacac tttttccctc actgatttct ttagaataaa
     3781 gaaagagctt ttcttttaag tcaggatagt catctatagt tgcttcattg tatactttac
     3841 taattgcatt taaaagtttt tcttctttag taaaatccat tataataacc tccctaccac
     3901 taccttctag gtgcccatgg accatgatta acccaaccat taacaataat ttttccaatt
     3961 tctcctttag cttgattcca atctacccaa catttttctt tgttacaata aagaccattt
     4021 ccatagtaag tagctgcatc aacttttatt cctgtaccga tgccagctag acaagttcct
     4081 aatattccta gaataacaca atgttttaat actttctttt tcatgattgt ttttcctttt
     4141 cgttttttta aaattgcttg ttatattaaa taatcttagt aattttatta tataacattt
     4201 tattatataa caatgattaa cgtcataaaa agtagttttg aattcataat cgtttaaata
     4261 aaattataag atcagttatt taaacagcta gtagacataa tgtcgactat gccaagtagc
     4321 ccctctatca agggctatag ctgctcactt tgtgattttt cattggtcta ggtcaaaagc
     4381 tttttttaag gcttggtttt ctgcggttgt ttctttctaa ttctttgtga atattgatcg
     4441 gtcatttttt aaatacttgt tatttttgtt tgtgtttgtt atgcttttta catatctcat
     4501 attcatttat tattcttttc taaggttaat aataggataa tctctttcag aaagactgct
     4561 cgtacgagca gtcttttctt atttatcaag tttttctaca aatacttcct cattttgact
     4621 gttgtagtaa ttaggattga gttttagttc ccctttttta tttcctttgt tggccactga
     4681 taataacatt gggctaaagc ttaatattcc tagtaggata gaaccgaata gcaagtgttt
     4741 ttttgtcata agtatttcct tcttcatttc catagctgcc accatttttt ccaattcttt
     4801 gtttgttcgt ccattgtttc tgttgcttca gaaagagtcg ttgaactatt ctctgaagac
     4861 tcttccgtat aagtcaactg cagttgctcc tgaagttttt cgatttgttg gttggcttgc
     4921 agggtgagtt gttgttgctg gtcgagtagt ttttgtatat gagaattatt ttgctctttg
     4981 agggcaagtt gttctcgtaa aaattcattt tcttcacgca actgatctag caacttgttt
     5041 gcaaccacgt ttttgtttgg tatataagca tttttatcgt tgttttgttc atgtttatgc
     5101 aacttatcta gcaacctttg attgtctaag ttgcgagcaa gttgcaatac tccagaacgc
     5161 aatacaacct tataaccacg ctcattttta gctatcatgg aagaatctaa tttttggata
     5221 tgtttcgata ttgcttgcct actcatctta aaaagatctg acaattcctt tattgtaaag
     5281 gtttcttgtg gttgcatact ggttgcctcc taggttgcta ctggaataaa ttatctaaat
     5341 cagataataa actttttttc tctttttccg aaagtgcgga ctctgtttgt ttttcaagag
     5401 cttttttctc tttttctagt tgtttgattt gttggaggag ttcaagttct cgtttcttct
     5461 gtttgatttt ttcgttaatt gttgtagcgg gttcttcgta ttctttttgt ttatcagcta
     5521 aagccaatgc tttattttgg tcttctttgg ttggtgcatg tttgttaaag tcgtctgctt
     5581 ttttgatctc aggtttgaac gtaaattgat agccaataac aggttttccc cgtccttttc
     5641 cgtatttctt tttgattgtt agtcctttga agattgcagt tagttcttga cgtataggtt
     5701 ttataactcg tttatctata tcaggttgct tataactttt aggaatatct aataattcaa
     5761 gaaagtcttc tttggagaaa tatgcgaaac ctttggttct gtattgcttt aacagacgaa
     5821 acatagtctt tgcatagcca ctttgtagct cgttgaattg ttgtaaagaa tagcgtaccc
     5881 actcgtctaa attatttaac aaaggcagtg ctttttcgta aattcgtata tctacgtaag
     5941 gattttctac gtccccgttg attttaaatt ctgtaaacat tacaaacata tcgtaagaaa
     6001 gcccagactc acttctacga ccaaagcgta aagataagat tttttcataa gttgctttta
     6061 aatcttctac aaatcgtaca tttgcagttg ctttgtagtt acttaaatct tttagttggt
     6121 caaacgtaaa acgaactgtc ttatcccctt tttcacgcat tctagacacg atgg
//
LOCUS       DAZKKZ010000108         6060 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.112, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000108 DAZKKZ010000000
VERSION     DAZKKZ010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6060)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6060)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6060
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.112"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            1497..2465
                     /locus_tag="ACG8LA_002741"
     CDS             1497..2465
                     /locus_tag="ACG8LA_002741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HFQ0204994.1"
                     /translation="MSNEIVKYHHELNTIPLRKFTPVEMNLFFSIVSRMRDVGDKKVQ
                     FTFEQLKDLSNYKATANVRFIDDLETTYDKLMDLRFGRRSADGLQRERFVLFNQFKID
                     GKSDIPFAEIQVHEKALPLLNNLEEWVRYSLQQFNELESSYSKTMFRLLKQYRTKGFA
                     YFSKEDFHELLDIPKSYNQGTIDQRVFNPIRQELTAIFKGLTIKKKYGKGRGKPVIGY
                     QFTFKPEIKKSDDFNKHAPTKEEQNKALELANQQVQSEKAPTSLQEKIKEQKRKLELL
                     QQLEKLEREQNTQNKENNAQKSEINSDIPSELKKDLLDNLQNLFKD"
     gene            2482..3006
                     /locus_tag="ACG8LA_002742"
     CDS             2482..3006
                     /locus_tag="ACG8LA_002742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HFQ0204995.1"
                     /translation="MTEKTIKELAEELGVSKTAINKKVSDENRKLWFSKIGNKFVINE
                     TGQKAIKSMFFNENENSNQQLVGEKTKTENHKNANQVPELEVLSLLEQQLNQKDMQLQ
                     EKDEQIKQMQKLLDHQQQLTLQANQQIEKLQEQLQLTYTEESSENKSTTLSEETESIE
                     KQSKAEKKWWQFWQ"
     gene            3382..3663
                     /locus_tag="ACG8LA_002743"
     CDS             3382..3663
                     /locus_tag="ACG8LA_002743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000353845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204996.1"
                     /translation="MDILVRNINPKIIARIDKRCQELTTKTGKKWSRNKYLKVLIESD
                     FDRQLMNYKKDQFDLLLEKFIAIQTENTNILNDYVHTNNQLIETLIGGI"
     gene            3665..4081
                     /locus_tag="ACG8LA_002744"
     CDS             3665..4081
                     /locus_tag="ACG8LA_002744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204997.1"
                     /translation="MRKTSVQKHVTLYPSHVDVLDSIIEKNPDVNNYSEAIRFLCMSY
                     EPDTNTTTTSNQAKLNAMGKEISIMTEIMAEFADLYLKDTGVLIGTNSKVYQEVKEKI
                     ENQLNPSRRNQPKNRQKETNQTFTSGNFDPTNFLKR"
     gene            4711..5865
                     /locus_tag="ACG8LA_002745"
     CDS             4711..5865
                     /locus_tag="ACG8LA_002745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="C47 family peptidase"
                     /protein_id="HFQ0204998.1"
                     /translation="MIILKPKKKIYLGLLFSLMIGIFSIGITNTYASENSNFNINSQP
                     IEEQAINFAKTDFEHSITSILLMENNTETDINYTLGSPFKMLDGENTANSSIFFPVFS
                     DADNTIKYIYTVKKNTNGEYSGSISQFLAKELQNLVDSNITDTTLFFQDNSIYYSDNG
                     QIKLLWKSPLSTEKNGVSSFTEKNDLISVNIKNKIKNFSKKQNFPAVKRVKSVSSGDN
                     FIMINWRIAETQTSFPWCAAYVEAAILCNKTDVRATSARAIMHYTYPNLNNSQIESKS
                     LNQDQIIKYANYCGVYPKKVARILNLSEVQTQLRKGNAIYMGTAGYGNYSNSRHALAL
                     FGWVNQGGYQTYYVWNPWYNYPTVISANAGPVTIPVPGGGFTWDNTITNW"
     gene            5838..>6060
                     /locus_tag="ACG8LA_002746"
     CDS             5838..>6060
                     /locus_tag="ACG8LA_002746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0204999.1"
                     /translation="MGQYHYKLVNKPIALVMGLVLVLFLTSCSKKQEIQKTDLIPFLG
                     TWQTKDHSERLVITNLNTSKNIEQYTILVK"
BASE COUNT         2292 a         1035 c          984 g         1749 t
ORIGIN      
        1 gttttcggtc tgtactgaaa tcaaggtatt attgggaatc ccagcttaaa tcatagatac
       61 cgtaagggat tttattcttt atttaaaact ttgcaacaga accaagagaa caatcataaa
      121 attcaaatca ttgataaaaa tttaaatata aatgaacaag ttttcattta caaagcaaca
      181 aataatttac taacactgcg ctctaataaa aaacaattag attacacttt tagtttggat
      241 tctccaaaaa agctcgtatt tattttgaca acgaatgatg ggacagaagg gacagctaaa
      301 ccaattgaat tttttaaagc tgattgatga atagttgttt gatattacaa aacaataatt
      361 tcaccgaagg tgaaacaagc gaaactttac aaaaagtggc tagcatttgc tagccttttt
      421 tgtattgtgg agcgtgggtt ttgaggggga ttcaaggggg agcttgcgcc cctttgacaa
      481 gcggttattt gcaccaaata cggaggtatt tggctagcaa atatagagct tgccaaacac
      541 tttagtgagt tttgtagaaa gtacctttaa aggtactttc acattacgaa cgatacgtcc
      601 gtaggacgta ctgaaagggt gggatttatg agcgaactaa tgcaaaattt ggctagcaaa
      661 aaaagttaaa aaatatatgc taataatcga gcgaaatgaa cactttttca agtgagcgaa
      721 tccgccatga caaagctgaa gcagtttatt tcagctttgt catggcgtgt gcctagactt
      781 ttaaaaaagt cggcacacga gcaaatatct ttatcaagct ctaatttgcg ttttaagacg
      841 tttgaaacgt ctaagtatat aaatatataa gagtaggttt aagagtgctt aaatcgaatt
      901 ttagagggca ttcagacaac tttagggttg ttagggcttg ccctgaccgc ctgtaaggcg
      961 ctttaagaac aagataaggg atttatacta agactgtctt aaaacgtctc aaacgaaggc
     1021 tcatagcttc tcaaagagtt ccttatgaac atttttagca aaggagccgg aagcgactgc
     1081 gcagtataat gtgagagcag agcgatcaca cctttttaag cgactgtagg gagtaagatt
     1141 cccagttgag aaaaatgcgc gaatctgttt ggagaaaaaa gaagtggttt tttaggcggg
     1201 aaattttgtc cccctctttt ataatctctt tttaaacctc tttttaaacc tctttaccgt
     1261 cggctatatc cttactctcc caagggaatg acgcttttat ctacatcgtt ttgtctgttt
     1321 atctacatcg ttttgtctgt ttatctacat cgttttgtct gtttatctac atcgttttgt
     1381 ctgtttgtac attgaattag tacatcgacg atgttaatat aagatgtaga taaacaggca
     1441 ttttgtattt cataacgtgt atctcttgtg cgagtaagaa aggagctatt ttaaatatgt
     1501 ctaatgaaat cgtaaagtat catcatgaat taaatacaat tccgttgcga aaatttacac
     1561 cagtcgaaat gaatttgttc ttttctatcg tatcaagaat gcgtgatgta ggtgataaaa
     1621 aagtacaatt tacattcgag caattaaaag atttaagcaa ttataaagca actgcaaatg
     1681 ttcgattcat agatgattta gaaacaacgt atgacaaatt aatggattta cgttttggta
     1741 gaagaagtgc tgacggtttg caacgtgaac gttttgtttt atttaatcaa tttaaaatcg
     1801 acggaaaatc tgatattcct tttgctgaaa tacaagttca tgaaaaagcc ttacccttac
     1861 ttaataatct tgaagaatgg gtgcgctatt ctctccaaca attcaatgaa ttagaaagca
     1921 gttattcaaa aacaatgttt cgattactaa aacaatacag aaccaaaggt ttcgcttatt
     1981 tttcaaaaga agactttcat gaattacttg atattcctaa aagttacaac caaggtacga
     2041 ttgatcaacg tgtgttcaat ccaatacgac aagaactaac cgcaatcttt aaaggtttaa
     2101 caatcaaaaa gaaatacgga aaaggacggg gaaagcctgt cattggctat caatttacat
     2161 ttaaacctga gataaaaaaa tcagacgact ttaacaaaca tgccccaaca aaagaagaac
     2221 aaaacaaagc attagaacta gctaaccaac aagttcaatc tgaaaaagca cctacttcat
     2281 tacaagaaaa aatcaaagaa caaaagcgaa aattggaact tttacaacag ttagaaaagt
     2341 tagaaagaga acaaaatacc caaaataaag aaaataatgc acaaaaatca gagataaatt
     2401 ccgatattcc ttcagaacta aaaaaagact tattagacaa tcttcaaaac ttattcaaag
     2461 attgaggggt ttttagattt tatgacagaa aaaacaatca aagaacttgc tgaagaatta
     2521 ggagttagta aaacagcaat taacaaaaaa gtttctgacg aaaatcgaaa actttggttt
     2581 tcgaaaatcg gaaacaagtt tgtgattaat gaaaccggac aaaaggctat aaaatcaatg
     2641 ttttttaacg aaaacgaaaa ctcaaatcaa caactagttg gcgaaaaaac gaaaaccgaa
     2701 aaccacaaaa acgccaacca agttcccgaa ttagaagtcc tttctctcct agaacaacag
     2761 ttaaatcaaa aagatatgca actacaagaa aaagacgagc aaataaaaca aatgcaaaaa
     2821 ttactcgacc accaacaaca actcaccctg caagccaacc aacaaatcga gaaactgcag
     2881 gaacaactac agttgactta tacggaagaa tcttcggaaa ataaatcaac gactctttct
     2941 gaagaaacag aatcgataga aaaacaatca aaggcggaga aaaaatggtg gcaattctgg
     3001 caataaaacc agcaatttaa attaataaaa attgctggtt ttattcttct ttttgctttt
     3061 gcgagcagag caacatggac ccatgttgcg atattttggt ggcgccccaa tccccgtttt
     3121 ttcgttgaat cttactcgga ctgcactcgt tttacagctg atttttctga attttgaaag
     3181 agcataagga aacgtggtat cactttctta cgaaaggtgc tagataggct gtgcctatca
     3241 cgtttctcag aaaaaaattt gctatcactt ttttgccatt gtggctaggc tatgtatagt
     3301 gttttggcga aaaatagcta tacaaatact atatttgtat ggtatacata aattatacgc
     3361 tgatacgaaa ggaaaatttc catggacatt ttagttcgaa atatcaatcc caaaattatt
     3421 gcaagaatag ataaacgttg tcaggaactc acaaccaaaa cgggcaaaaa atggagtcga
     3481 aataaatatc taaaagttct aatcgaaagt gattttgacc gtcaacttat gaattacaaa
     3541 aaagatcaat tcgatttatt actcgaaaaa tttattgcca ttcaaacaga aaatacgaac
     3601 atactgaatg actatgttca cacaaacaac caactcattg aaacacttat cggaggaata
     3661 taacatgaga aaaacttctg ttcaaaaaca cgtaaccctt tatcccagtc acgttgacgt
     3721 tttagattcc atcatcgaaa aaaatccaga cgtcaacaat tattcagaag ccattcgttt
     3781 tttatgtatg agttatgaac ctgataccaa tacaaccaca accagtaacc aagcaaaact
     3841 caatgccatg ggaaaagaaa tttctatcat gacagaaatc atggcagaat ttgctgattt
     3901 atatctaaaa gatactggtg ttcttatcgg tacaaattct aaagtgtatc aagaagtgaa
     3961 agaaaaaatt gaaaatcaac tcaatccttc ccgacgaaat caacccaaaa atcgtcaaaa
     4021 agaaaccaat caaaccttta cttctggaaa ttttgaccca acaaactttc taaaaagata
     4081 aaaaaagaaa ccgatcccta aaaaaattcc tcgatttctt tttagggatc agtcttccag
     4141 caagatttgc aagttggtac caacttgcga aaaaaaagaa aaatccgctt atgcaacttc
     4201 ttctttttgt attttggggc gctaccccaa tccccaagta tcggttattt aatagcgcgg
     4261 aaatccaaag aataggacgt accctgaaac aaaaaaagac tgctctcacg agcagcccaa
     4321 aatgagatta tcctattcat caacataaaa atattacaaa gtgaagaact agagaaagac
     4381 aaaaaaagca tatcaaatcc tctcaaaaat aacaagtctt taaaaaatga cagataaaaa
     4441 tgcacaaaga actaaaaaag agaaatcgcg taaaatcaag cattagaagc tagtaactag
     4501 ctagaccaat taaaaatcac aaagtgagcg tctctatcca ttggtagagg ggctacttgg
     4561 tctagtcgac attatgttaa ctagctcgat aaataacgat tatgttccca aaacaatatt
     4621 ttatgaacta taacaaaaat ttgttatcgc atattgtata ttttaattat ataattatag
     4681 gtgtatacca cttaaattta acacaaagac gtgattattt tgaaacccaa aaagaaaatt
     4741 tatctaggtc tcctcttttc cttgatgatt ggaattttta gtataggaat tacaaatacc
     4801 tatgcttcag aaaattctaa tttcaatatc aactcccaac caattgaaga acaagcaatt
     4861 aattttgcga aaactgattt tgaacactcc ataacttcaa ttcttttaat ggaaaataac
     4921 accgaaactg atattaacta tactcttggt tcgccattta aaatgctcga tggagaaaat
     4981 acggcaaata gttctatttt ctttccagta ttttcagacg ctgataatac gattaaatat
     5041 atttataccg tcaaaaaaaa tacaaatgga gaatattcag gaagtatctc acaattttta
     5101 gcaaaagaac ttcaaaatct agtagatagt aatataacag atacaacctt attttttcaa
     5161 gataatagca tttattattc cgataatgga caaattaaac tactttggaa atcaccttta
     5221 agtacagaaa aaaatggtgt ttcttccttt acagaaaaaa atgatcttat atccgtaaat
     5281 ataaaaaata aaattaaaaa tttctctaaa aaacaaaatt ttcctgcggt taaacgtgta
     5341 aaaagtgtct cctccggaga taactttatt atgattaatt ggcgtatagc agaaacccaa
     5401 acaagttttc cgtggtgtgc tgcttacgta gaagctgcta tcttatgtaa caaaacagat
     5461 gtacgtgcta cttcagctag agccattatg cattatacct atcctaattt aaacaacagt
     5521 caaattgaat caaaaagtct taatcaagat caaataataa aatatgcaaa ttactgtggt
     5581 gtttatccta aaaaagtagc acgaatacta aacctttcag aggtccaaac acaactaaga
     5641 aaaggaaatg ccatttatat gggaactgct ggttatggaa attatagtaa cagccgtcat
     5701 gcacttgcat tatttgggtg ggtcaatcaa ggtggttatc aaacttacta tgtgtggaat
     5761 ccttggtata actacccaac tgtaataagt gcaaatgcag gaccagttac aattcctgta
     5821 cctggaggtg gttttacttg ggacaatacc attacaaatt ggtaaataaa cccattgctt
     5881 tagttatggg tctagtgtta gttcttttct taactagttg ttcaaaaaaa caagaaatac
     5941 aaaagactga tctgattcct tttctaggaa cttggcaaac taaagatcat tcagaacgtc
     6001 tagtaatcac taatttaaat acttcaaaaa atatagaaca atataccatc ttagtaaaag
//
LOCUS       DAZKKZ010000109         5973 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.113, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000109 DAZKKZ010000000
VERSION     DAZKKZ010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5973)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5973)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5973
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.113"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(131..1057)
                     /gene="glsA"
                     /locus_tag="ACG8LA_002747"
     CDS             complement(131..1057)
                     /gene="glsA"
                     /locus_tag="ACG8LA_002747"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004359 - glutaminase activity [Evidence
                     IEA];
                     GO_process: GO:0006541 - glutamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
                     /protein_id="HFQ0205000.1"
                     /translation="MEVKELEQLIGKNFHYYQTGQVADYIPALAEVDPKQLGMAIYDL
                     DTKQLIEGGDADVRFAIESMSKVPVLLLAIKDNGIEKVFQTINTEPTGFAFNSIMNME
                     INHRKHPMNPFVNAGAIATTSLIAGKDADEKFERILSFMKEICDDPNITLNEEIYHSE
                     SRTGDINRSLAYYMKGNQMIEGDVPEILDAYFRQCSLNVTATGIAKLAAVLANKGIAP
                     WNGKQIITEESATIVKSIMTTAGLYDESGEFSVHVGVPAKSGVGGGLMAAVPNRYGIG
                     VFSPALDPFGNSAAGIQLLKDVVKELDADIFE"
     gene            complement(1080..2507)
                     /locus_tag="ACG8LA_002748"
     CDS             complement(1080..2507)
                     /locus_tag="ACG8LA_002748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFQ0205001.1"
                     /translation="MQQSKTKIPAKKLTFFGFLAMTISMVVSLYEYPTFATSGFSLVF
                     FLLLGGLLWFIPVALCAAEMATVKGWEKGGVYTWVSRTLGKRFGFAAIFFQWFEITVG
                     YLTMLYFLTGALSYATGIGAIQNNKYLKLAILLIIFWAILLSQLKGTKYTSLIARIGF
                     VAGILLPALVLFGLGIHYVASGAPLQTILSMKTLIPDFSKLPTLVVFVSFILAYMGVE
                     TSASHANEMENPKKDYPLAMFVLVILAIILDTFGGLTVATTVPQHGLSLNTGVIQSLE
                     FLLRHIDPNLAWIAKILAILVCLGVIGEIASWVTSPSKALHVAAEEGLLPEYFAKENT
                     HGVPAHLMIANGIVATIWAAVFTLSGGGNNLSFLAAMSLTVVIYLMLYFMFFAGYLKL
                     VFKDDSLERAYQVPGGKVVKVIVACLGLLTSLFAFCISFVPPASIAAGQHGIYETILI
                     VSYLIVLVIPFTIYACRHKFQHAEK"
     gene            complement(2538..3752)
                     /locus_tag="ACG8LA_002749"
     CDS             complement(2538..3752)
                     /locus_tag="ACG8LA_002749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008519 - ammonium channel activity
                     [Evidence IEA];
                     GO_process: GO:0072488 - ammonium transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter"
                     /protein_id="HFQ0205002.1"
                     /translation="MNTLPINTGDTAFMILCTAMVCLMTPGLAFFYGGLARKNNILTI
                     MSQSFLSVGITTIMWVFGGFGLAFGRDIGGVIGNPADFFLMRHVTSFPNMFHGATIPF
                     LMFFLYQLMFIVITVPLMTGAFAGRLNLKGYIILVIFWNLLIYFPVCHWIWGGGFLDQ
                     MGFRDFAGGAVIHTTAGFGSLACILTLGQRKIPLGERSQHSSLMAAAIGTGLLWFGWF
                     GFNSGGALRADEQAVNAFGSTFIALAFAMITWLIIAKVKGNGFDFVDVLTGSVAGLAA
                     ITPCAGYVEAKSAMLIGIIAGIVCHAAVDFRKKKQWDDALDVWGVHGMGGFTGTILIG
                     IFASNSHLLTNPSSWYFLGIQVIGVIITAVYAYVLTTVILKSAMHFTTITTTKEEQEE
                     GLDFFFFGNKLN"
     gene            complement(3838..4065)
                     /locus_tag="ACG8LA_002750"
     CDS             complement(3838..4065)
                     /locus_tag="ACG8LA_002750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0205003.1"
                     /translation="MKNKFENRSDTRCGSFLYILYEVFFIPYEKISLKIKKDENKRFS
                     IKRRPFIFCLYLCEKRKRAQHIKLLLIVCLL"
     gene            complement(4093..4335)
                     /locus_tag="ACG8LA_002751"
     CDS             complement(4093..4335)
                     /locus_tag="ACG8LA_002751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HFQ0205004.1"
                     /translation="MGFIWALIVGGIIGAIAGAITNKGSSMGIIANIIAGLVGSAIGQ
                     ALLGTWGPTIAGMAIIPSLIGAIILVLVVSFFARKL"
     gene            complement(4367..4924)
                     /locus_tag="ACG8LA_002752"
     CDS             complement(4367..4924)
                     /locus_tag="ACG8LA_002752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HFQ0205005.1"
                     /translation="MENKNMNTTNGSVLANEKGENRMMNGELTYEDKVIQKIIGYALK
                     DVDGLLTLDGGFFSNMAEKLVNTDNVTAGINTEVGKKQVAVDLDVIVEYGKDIEDIYN
                     QIKELISTEVNNMTHLDVIEVNVNVADIKTQEEYQKDQETVQDKVTEAAKSTGQFASR
                     QTDKAKSAVGKGAQKVKENNEPRVQ"
     gene            complement(4937..5125)
                     /locus_tag="ACG8LA_002753"
     CDS             complement(4937..5125)
                     /locus_tag="ACG8LA_002753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HFQ0205006.1"
                     /translation="MKELFSAYKLPIIFGGLGLLLAVLWLTIGFFKTLLIIIMTAIGA
                     GIGFYLKQSGIVDQFFKS"
     gene            complement(5138..5704)
                     /gene="amaP"
                     /locus_tag="ACG8LA_002754"
     CDS             complement(5138..5704)
                     /gene="amaP"
                     /locus_tag="ACG8LA_002754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HFQ0205007.1"
                     /translation="MNKGLKIIGVIMSLLLLSVFLAIALINAPYIMPEQLERFRFFTL
                     TNYYMQQYIFWAAVVFAVLAIIILLVVLFYPKSRGTFVMKREDGKLTIDKKAIEGLVR
                     SHLHEEEFIHSPKVRIRSTKNRIHIHVNGDLKRTSSLVGKTGVLMQDIEEEVTKVLGT
                     KETVKVAVTYSGYEEQEDTRDYKHSRVE"
BASE COUNT         1810 a         1262 c         1025 g         1876 t
ORIGIN      
        1 ttagaaaagc cctttcaaaa accaataaaa aaagaaactg ggacaaaagt caaacaagct
       61 cacaatttca gcctcattgt aggtagcttt gagccgtttg gacttttacc ccagcctctt
      121 tcaagaatgg ttattcaaag atgtcagcgt ctagttcttt gactacatct ttcaacaatt
      181 ggataccagc tgcgctgtta ccaaatggat ctagtgccgg gctgaagaca cctatgccgt
      241 aacgatttgg cacagctgcc atcaacccgc cgcctacacc gctttttgca ggtacaccaa
      301 catggacgga aaactctcct gattcatcat acaaaccagc agttgtcata attgatttga
      361 cgattgtagc actttcttca gtaatgattt gtttgccatt ccaaggagca attcctttat
      421 ttgccagcac agcagctaat tttgctatgc ctgtagcggt gacattgagg gagcattgtc
      481 tgaaataagc atcgagtatc tccggtacgt ctccttcgat catttgatta cctttcatat
      541 agtaagcaag agagcgattg atatcacctg ttcttgattc agaatgatag atttcttcat
      601 tcaatgtgat attaggatca tcacagatct ctttcataaa tgacaagatt cgctcaaatt
      661 tttcatctgc atctttaccg gcaatcaacg aggttgttgc aatcgctcct gcattaacaa
      721 aaggattcat tggatgtttg cgatgattga tttccatatt catgatagaa ttgaaggcaa
      781 aaccggttgg ttccgtgttg attgtttgaa agactttttc tattccgttg tctttgattg
      841 ctaataacaa tacgggaact tttgacatgc tttcgatggc aaagcgcaca tcggcgtctc
      901 ctccctcaat cagttgtttt gtatccaaat cataaatcgc catacctaat tgtttgggat
      961 ccacttcagc taatgctgga atgtaatccg ccacttgtcc tgtttgataa tagtggaaat
     1021 tttttccaat caattgttct aattctttta cttccatttg aataaccagc tttcattttt
     1081 tatttttctg catgctggaa tttatgacgg catgcgtaga tcgtaaatgg aataactaag
     1141 acgataagat aagaaacaat cagaatcgtt tcataaatcc catgctgtcc agctgcgata
     1201 ctagcaggtg gaacaaatga gatacaaaaa gcaaaaagtg aagtcaaaag acctaaacaa
     1261 gcaacgatta cttttacaac ttttccgcct ggaacctgat aggctctttc aagactgtca
     1321 tctttaaaaa ccagcttcaa atagcccgcg aaaaacataa agtacaacat caggtagatt
     1381 acaacagtca atgacatcgc tgcaagaaat gaaagattat tccccccgcc gcttaatgta
     1441 aagacggctg cccagattgt tgcaacgatc ccatttgcga tcatcaaatg agcaggaaca
     1501 ccgtgtgtgt tttcttttgc aaaatattca ggaagtaatc cttcttctgc tgctacgtga
     1561 agtgcttttg aaggagaggt tacccaagaa gcaatttctc cgatgacacc taaacaaaca
     1621 agaatcgcaa gaattttcgc aatccatgca agatttggat caatgtgtct taataggaat
     1681 tctaacgatt gaatcacccc tgtattaaga gacaaaccat gttgaggtac tgtagtagcg
     1741 acggtcaatc cgccaaaagt atctaaaatg attgccagaa taaccaatac aaacattgct
     1801 aatggataat cctttttagg gttttccatt tcatttgcat gactggcaga tgtttctacg
     1861 cccatatatg ctaaaataaa ggaaacaaaa acaaccagcg taggcaattt cgaaaaatca
     1921 ggaatcaatg ttttcataga cagtatcgtt tgtagtggag cgcctgaagc gacataatgg
     1981 atccctaagc caaacaagac taatgctggc aacaagatac cagctacaaa accgatccga
     2041 gcaatcaatg aagtgtattt ggttcctttt aactgtgaga gtaaaatagc ccagaaaata
     2101 atcaatagga ttgccaattt cagatattta ttgttttgta tagcaccaat acccgttgca
     2161 taggataatg caccagttaa gaaatacagc atggtcaagt agccaactgt tatctcaaac
     2221 cattggaaaa agattgcggc aaaaccgaat cgttttccca atgtgcgact gacccaagta
     2281 tagacaccgc ctttttccca tcctttcacc gttgccatct ctgctgcgca caatgccaca
     2341 gggataaacc atagcaaacc gcctaataac aagaaaaata ctaagctgaa gcctgaggtc
     2401 gcgaatgtgg gatattcata taatgaaacg accattgaga tggtcatagc caaaaagcca
     2461 aagaacgtta atttttttgc aggaattttc gttttgcttt gttgcatgaa tcttcctctt
     2521 ttctatttga atttgtttca attgagtttg ttgccaaaga agaaaaagtc caatccttct
     2581 tcttgttctt cttttgtagt agtgatcgtt gtaaagtgca tcgccgattt taaaatcact
     2641 gttgtcagca cataggcata cacggcagta atgatgacac caatcacttg aatccctaag
     2701 aagtaccagc tgcttggatt cgttagtaaa tggctgttag atgcaaagat ccctatcaga
     2761 atcgtacctg tgaatccgcc catgccatga acaccccaca catcaagtgc atcatcccat
     2821 tgtttctttt tacgaaaatc aacagcagca tgacagacga tacccgcaat gatcccaatc
     2881 agcatggcac tttttgcttc tacataaccg gcacaaggcg taatggctgc caatccagca
     2941 acggatcctg ttagtacgtc gacaaaatca aagccatttc cttttacttt tgcaatgatc
     3001 agccaagtaa tcatcgcaaa tgcaagagcg atgaatgttg aaccaaatgc attgactgct
     3061 tgttcatctg ctcgaagtgc accaccggaa ttaaaaccga accagccaaa ccaaagcagt
     3121 cctgtaccga tagcagctgc cataagactg ctatgctgac ttctttctcc taaaggaatc
     3181 tttctttgac caagtgtgag gatacatgct aaagagccga atccagctgt cgtgtggatg
     3241 actgctccac cagcgaaatc tctaaatccc atctgatcca aaaatccgcc accccatatc
     3301 cagtggcaaa cagggaaata aatcagcaga ttccaaaaaa taacaagtat aatatagcct
     3361 tttaaattca atctccctgc aaaagctcct gtcatcaaag gaacggtaat cacgataaac
     3421 atcagttggt aaagaaagaa cattaaaaat ggaatcgttg caccatgaaa catgttgggg
     3481 aagcttgtaa catgtctcat caaaaagaaa tctgccgggt ttccaataac accgccgata
     3541 tcccgtccaa aggccaatcc gaatccacca aatacccaca taatcgttgt tatcccaacg
     3601 gagagaaaag attgagacat gatcgttagt atattattct tccgtgctaa tccgccgtaa
     3661 aaaaaagcta gaccaggagt catcaggcaa accattgctg tacataaaat catgaatgct
     3721 gtatctcctg tattgatagg taatgtattc atttttttcg cctcctttct acgattacga
     3781 gtataaaaga aggtgtagtt gtttttttct tctgtttttt tgaattaata cttgcattta
     3841 taaaagacag acaattaata aaagcttgat gtgttgtgct ctttttcgtt tttcacacaa
     3901 ataaagacaa aaaataaacg gtcttctttt tatagaaaac cgtttatttt cgtctttttt
     3961 tatttttaaa gatatttttt cataaggaat aaagaatact tcatataaaa tatataaaaa
     4021 agaaccgcag cgagtgtcgc tacggttctc aaatttgttc ttcatttcaa cataagtttt
     4081 tcttcaattt gcttataatt tacgtgcaaa gaatgaaacg actaatacta aaatgattgc
     4141 accgatcaat gatggaatga tagccattcc tgcaattgtt ggtccccaag ttcctagtaa
     4201 agcttgtcca attgctgaac ctactaaacc agcaatgatg tttgcgatga tccccattga
     4261 tgatccttta ttcgtgattg ctcctgcaat tgctccaatg ataccgccga cgattaatgc
     4321 ccaaataaat cccattttaa attcctccta actgacttct tacttcttat tgtacacgtg
     4381 gttcgttatt ttctttgact ttttgtgcac ctttgcctac agcagatttt gctttatctg
     4441 tttggcgtga agcaaattgt cctgtggatt ttgctgcttc tgttactttg tcttgtactg
     4501 tttcttgatc tttttggtat tcttcttgtg ttttgatgtc tgcaacattc acattcactt
     4561 cgataacatc taaatgtgtc atattgttta cttcagtact gatcaattct ttgatttggt
     4621 tgtaaatatc ttcgatgtct ttaccgtatt ctacgatcac atctagatcc acagctactt
     4681 gtttcttacc tacttctgta ttgatacctg ctgttacgtt atctgtgttg actaattttt
     4741 cagccatatt tgagaaaaat ccgccatcta atgtcaatag accatctaca tctttcaatg
     4801 cataaccgat gattttttgg atgactttgt cttcataagt caattcacca ttcatcatgc
     4861 ggttttctcc tttttcattt gccaaaactg atccatttgt tgtattcatg tttttgtttt
     4921 ccatctttgt ttcctcctat gatttaaaaa attgatcaac tattcctgac tgtttcaaat
     4981 aaaaaccgat tcctgcgcca attgctgtca tgattatgat caacaatgtc ttgaaaaatc
     5041 caatcgttaa ccataaaaca gctagcagta gtccaagacc cccaaagata atagggagct
     5101 tgtatgctga aaatagttct ttcattattt ggccctccta ttccactcga gagtgcttgt
     5161 agtctcttgt atcttcttgt tcttcataac cgctgtatgt gactgccact ttgaccgttt
     5221 cttttgttcc gagtacttta gttacttctt cttcgatatc ttgcatcaat acacctgttt
     5281 tccctactaa tgaagaagtt cgtttcaagt ctccgttgac atggatatgg attcgatttt
     5341 tcgttgaacg tatccgtact ttaggtgaat gaatgaactc ttcttcgtgt aaatgggaac
     5401 gtaccaaccc ttcgatcgct tttttgtcga ttgttagttt gccatcttcc cgtttcataa
     5461 cgaaagttcc tcttgacttt ggatagaaaa gaacgactag caagatgata atagcaagaa
     5521 cggcaaatac tacagctgcc cagaaaatat attgttgcat gtagtaattc gttaaagtaa
     5581 agaagcgaaa tcgttccaat tgttcaggca taatatacgg cgcattgatc aacgcaatcg
     5641 ctagaaatac tgaaagtagc agtaaactca tgataacacc gattattttt aaccccttat
     5701 tcattttcca cctcctataa acttattttt accctgtaaa taactctacc gacaatcaca
     5761 gtatagatag cgaacagtta gcatagcatc agtaaataaa gcgctaccaa acattgctgg
     5821 atcataacgg cgttttattg ccagtctgat actgaaataa caattgctta cttattctct
     5881 atttactttt gattgctggc tatacttaaa ggatattatt caagattaaa aattgcaaag
     5941 attatgctca gttattatta caagattcta ttt
//
LOCUS       DAZKKZ010000110         5769 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.114, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000110 DAZKKZ010000000
VERSION     DAZKKZ010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5769)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5769)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5769
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.114"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..300)
                     /locus_tag="ACG8LA_002755"
     CDS             complement(<1..300)
                     /locus_tag="ACG8LA_002755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6056 family protein"
                     /protein_id="HFQ0205008.1"
                     /translation="MNKHNRKITNNKELILLLIGIWGIFLLFNMYMPTMRADDVVYAS
                     RLDELGYLGASIEHYKTWSSRIIIELFLMFFSKHFMLWKLLNSTIMLGIVVLLCKY"
     gene            393..742
                     /locus_tag="ACG8LA_002756"
                     /pseudo
     CDS             393..742
                     /locus_tag="ACG8LA_002756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741963.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
     gene            complement(1014..1304)
                     /locus_tag="ACG8LA_002757"
     CDS             complement(1014..1304)
                     /locus_tag="ACG8LA_002757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0205009.1"
                     /translation="MEKKYGTVDKIRTLQVSARPLIRFSLNGVNCLIASHSLNFLAEV
                     DEGMKLVVTGYYNNRKQFVVRSYHVLGKPKIVVEYEKSLYPRKKVRQDERIN"
     gene            1706..1942
                     /locus_tag="ACG8LA_002758"
     CDS             1706..1942
                     /locus_tag="ACG8LA_002758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001159903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0205010.1"
                     /translation="MQFLEPKNKNAKSVDWEISEQVRVIVKQYAEYAERTESEAVDEF
                     LLNILDDKKFIEWIANKRSNKRIVEKMGIKDRVG"
     gene            1949..3901
                     /locus_tag="ACG8LA_002759"
     CDS             1949..3901
                     /locus_tag="ACG8LA_002759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017431446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insertion element protein"
                     /protein_id="HFQ0205011.1"
                     /translation="MTKLKRLATKEDEIVDVKIPISNEELKDRAKQYDLLTPKRFATR
                     YNKMLFLPTSFKWNGSEYPIQYNYCINPFCCNFGKEQHKFKDVKGKPSRYKMTGSSKD
                     KGHKGMYCNDNPIGRGVSQNCTVTPLSNWSVVEEIKRLIEINSIQDVEPDYQFHKEGC
                     SEEESTPFNEPKQFYKRGKSRGKSQRYQCKACKKFTNVLPKREETTTYHQQKNTILPM
                     FAKMVVGRVSVSRTCDILGIGVGTYYHKLEWLYRRCLEFLERYETQPLQTKKFNEMWL
                     NTDKMHYYLNNVRKKGQGSKKYTGFEDLNMQTYIVVSAEVLSRYVFRSDVAYDWNISM
                     DELNEDTRKFKEDHLNTFSRKNDRLDWSYYPQEPSANDSENRNAYLHELGKITNRSRF
                     VDGLNVDAPYTTTAHYWLIKQMVNADEWRMISDDDFSIRNAFYRVFTKELRLSDAHHF
                     ICQVNKTKSRKQCLKEFGQAKAELLDWGDIRGFKTKFLRTLASHYLTELLTSHQFHEE
                     AISKDGERYRKYADNPIKHPLATKDKGFYSVDCRTDLSALEPNEIAKMLLNVNDHSTN
                     SFIQQIRRYISSLERPLTTARGDKKSYIYANFNPKYAQFAITILRTYYNFCRPFKSAD
                     KKVLTPAQRLGITDKQFDWKDIIYFK"
     gene            complement(3973..4470)
                     /gene="dfrG"
                     /locus_tag="ACG8LA_002760"
     CDS             complement(3973..4470)
                     /gene="dfrG"
                     /locus_tag="ACG8LA_002760"
                     /EC_number="1.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004146 - dihydrofolate reductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrG"
                     /protein_id="HFQ0205012.1"
                     /translation="MKVSLIAAMDKNRVIGKENDIPWRIPKDWEYVKNTTKGHPIILG
                     RKNLESIGRALPDRRNIILTRDKGFTFNGCEIVHSIEDVFELCKNEEEIFIFGGEQIY
                     NLFFPYVEKMYITKIHHEFEGDTFFPEVNYEEWNEVFAQKGIKNDKNPYNYYFHVYER
                     KNLLS"
     gene            complement(4797..5489)
                     /locus_tag="ACG8LA_002761"
     CDS             complement(4797..5489)
                     /locus_tag="ACG8LA_002761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HFQ0205013.1"
                     /translation="MKKKFITGGIVVAFLCLIGYTGTRYANEIILWGGETDIDTINEN
                     LTQLDHTLTDKEQAITDLTARLAQKEQTLQDSKADVQEYQTKVNELENQKNQSAAEKQ
                     NLESQLVSKDAQLQSKQNEINVKLDEINQKNDEINHLNADWTARLQEAQAKLSELQNT
                     VNGLNQQIATLTQEKTNVETQLTDTQKKLDEATAENSSLKQYIQKLEKAKDEVEDTAD
                     KSQQIVEEHLRK"
BASE COUNT         1894 a          996 c          917 g         1962 t
ORIGIN      
        1 atacttgcaa agtaatacta caattcctaa cataatcgta gaatttaata atttccatag
       61 cataaagtgt ttagaaaaga acattaagaa tagttctata ataattcttg aactccatgt
      121 cttataatgt tctatcgaag cacccaaata gccaagttca tctaatctac ttgcataaac
      181 tacgtcatcc gctctcatag tcggcatata catattaaag agtaaaaaga taccccaaat
      241 ccctattagt aacaagatca gttctttgtt attcgttatt tttctattat gtttgttcat
      301 ttttatactc cttcttatat ttcctaatag agtataacat agctttaagc attacttaaa
      361 gataacttaa aagttatctt ttaaatactt aattgttaaa taccttattt gatgcaaaag
      421 aaatctacga tagtcaacaa aaaaattttc attatatcca gaaaaatttt tcttagttaa
      481 ggacctatgg attgcagtaa tgcagaattc gtcgaataaa ctgccaaaga catacaatca
      541 tattgctttt aaaattgacg aacaagatat agattcgttt gtctcaaaaa tccaaatgtt
      601 aggtttaact gtcgaaccag gacgttctcg tgtgaaaggc gaggcttctt caatttactt
      661 ttacgactat gataatcacc tcttcgagtt acataccggt actctccagg aacgtttaaa
      721 atcctacaat tccactacct gagactagta atgactagtc tctttttatg gcctctgatc
      781 cccccattga gcgaatacta atagggcttc gaattgatct gttcaatctt taagcaatat
      841 ccctcaaatg agtttggaaa gtttagtgat tcatcacaaa tacttaaata catgtagtta
      901 tatatagatt gaggttcttg tgagcgtatg ctcgtgtggg ttcaaatccc atcgtctgca
      961 tccatctttc caaaacaagc ggctaggaca tttttgtctc agccgcttgt tttctagttt
     1021 attctttcat cttgtcggac cttttttctt gggtatagac ttttctcata ttctaccaca
     1081 attttgggtt tccctaacac atgataggat ctcacaacaa attgctttct attattataa
     1141 taacctgtaa cgactaactt catcccttcg tctacttcag ctaggaagtt caaactatgg
     1201 gaagcaatca aacaattgac cccatttaaa ctgaaacgga tcaacggtct ggcactaact
     1261 tgcaaagtac ggatcttatc tactgttcca tattttttct ccataacctt cacctcaata
     1321 ccattatacg aacatacatt ccctttgtaa agaagaaact ctgttttatc tttttgactt
     1381 tttgtctatt acctttctta aaatcatatt ggcacttcct gcgaagatga aggacatgta
     1441 ctaaaaaaaa gaggcagcag tatagattta agtagttcag ttttggagta caaaaagtga
     1501 aaatgtaaac ctaaatgagt atcaaattgc aactgaattt gatactcgtt ttttattgtt
     1561 aaatcaacgt ttgttgttaa tttacaccac aaaatgtaag ttaaaatgta tataaaaatg
     1621 cgaacgtgaa ataattattg taggaatgca aattggtgtg ttaaaatggt tacaatttac
     1681 taagcaaaaa ggggtgcatt ttcctatgca atttcttgag ccaaaaaata agaacgctaa
     1741 gtctgtggat tgggaaatat cagagcaagt aagggtgata gttaagcaat acgctgaata
     1801 tgcagagcgt actgaaagcg aagcagtgga tgaattctta ttgaacattt tagacgataa
     1861 gaagtttatt gaatggattg ccaacaagcg aagtaataag cggattgttg aaaaaatggg
     1921 tatcaaagat agagtgggtt gatagacaat gaccaagctt aaaagattag ccacgaagga
     1981 agatgaaatt gtagatgtta aaattccgat ttcaaacgaa gaattaaaag atagggctaa
     2041 acaatatgat ttattaactc caaaacgatt tgcaacaagg tataacaaaa tgttgttctt
     2101 gccaacgtct tttaaatgga acggttctga atatcccatt caatataatt actgcatcaa
     2161 tccgttttgt tgtaattttg ggaaagaaca gcacaaattc aaagatgtaa aagggaaacc
     2221 aagtcgatat aaaatgactg gtagttccaa agataaaggt cataaaggta tgtactgcaa
     2281 tgacaatcct attggcagag gtgtatcgca aaactgtaca gtaacccctt tatctaattg
     2341 gtctgttgtt gaagaaatta aacgccttat agaaatcaat agcatccaag atgttgagcc
     2401 agattatcaa tttcataaag aaggctgctc ggaagaagaa tcaaccccat tcaatgagcc
     2461 gaagcaattt tacaaaaggg ggaaaagtag gggcaaatct caacgctatc aatgtaaggc
     2521 gtgtaagaag ttcactaatg ttctaccaaa aagagaagaa accactactt atcaccaaca
     2581 aaagaacacc attcttccaa tgttcgctaa gatggttgtt ggaagggttt cagtcagtcg
     2641 tacttgtgat attttaggaa ttggagttgg aacctactat cataagctgg agtggctgta
     2701 taggcgttgt ttggagtttt tagaacgata tgagacacaa ccccttcaaa caaagaaatt
     2761 taacgagatg tggcttaata cggacaagat gcactactac ctaaataacg tccgtaagaa
     2821 aggacaaggt tcaaagaaat atacggggtt tgaagacctt aatatgcaaa cgtatatagt
     2881 tgtatctgct gaggtcttat caagatatgt gttccgttct gatgttgcct atgattggaa
     2941 tatttcaatg gatgaattaa atgaagatac aagaaaattc aaagaagacc atctcaatac
     3001 ttttagtcgt aaaaatgata ggttagattg gtcttattat ccacaagaac catccgctaa
     3061 cgatagcgaa aataggaatg cttatcttca cgaattaggg aaaattacta ataggagtag
     3121 atttgtcgat ggtttaaatg ttgatgctcc ttatactaca actgctcact attggttaat
     3181 taaacaaatg gttaatgccg acgaatggcg aatgattagt gatgatgact tctctattag
     3241 aaacgccttt tatagagtat tcacgaaaga attaaggttg agcgatgcac atcattttat
     3301 ttgccaagtt aacaagacga aaagcagaaa acaatgctta aaagaattcg gacaagcaaa
     3361 agcagaactg ctcgattggg gagatatcag aggattcaaa acaaagtttc tacggacttt
     3421 ggcatctcat tatctaactg aattactaac aagtcatcaa ttccacgaag aggctattag
     3481 taaagatgga gaaagatatc gcaaatatgc cgataaccct atcaaacatc cattagccac
     3541 taaggataaa ggattttatt cagttgattg tagaacggat ttatctgctc tggaaccaaa
     3601 cgaaatcgca aagatgctat taaatgttaa tgaccattcg accaatagct ttattcaaca
     3661 gataagacgt tatatatcat ctcttgaaag accattaaca acagctcgtg gtgataagaa
     3721 gagctatatt tacgctaact tcaatccgaa gtatgctcaa tttgcgatta caattctaag
     3781 aacttactac aacttttgtc gcccttttaa atcagcggat aaaaaggttt tgacacctgc
     3841 tcaaagatta gggattacag ataaacaatt tgattggaaa gatataattt atttcaaatg
     3901 acaaaaagag cttggagtaa tcccaagctc ttgtgcttta tctttactgt tcttcttcaa
     3961 ttaacgcacc cgttaactca ataagttttt tctttcatat acatgaaaat agtagttata
     4021 cggattttta tcattcttta tccctttttg ggcaaatacc tcattccatt cctcataatt
     4081 cacttctgga aaaaaagtat ctccttcgaa ttcatgatgt atttttgtga tgtacatttt
     4141 ctcaacataa gggaaaaaca aattataaat ctgttctcct ccgaaaataa aaatttcttc
     4201 ttcgttttta cataactcaa aaacatcttc tattgaatga acaatttcac aaccattaaa
     4261 ggtaaacccc ttatctctcg tcagaataat atttcttctg tcaggtaagg ctcttccgat
     4321 tgattcaagg ttcttcctac ctaatattat cggatgtccc tttgtagtat ttttaacata
     4381 ttcccagtcc ttgggaatcc tccaaggaat gtcattctct ttgccaatca ctctattctt
     4441 atccatcgca gcaatcaaag aaactttcat ttataacaca gcctttttaa ctaatttacc
     4501 atctaatttc ttatttctat caaaaaacct tttctcatta tcctgcccgt tagttgaata
     4561 agcaattttt tctataagtt atattatcat aataccacaa aatcacaaat tttcattcaa
     4621 ttatcatttt caattgcatt ttataaatca ttttgtatgt aatttggtat gtaagttaaa
     4681 atgaaaaaag tagtccattt tgaagtacat tttgtcattt tgtactccaa aactgaacta
     4741 cttagtatag attactgttg cttctttact aatttaggtt tacttgttaa gaaagattat
     4801 ttacgcaaat gttcttcaac aatttgctga gatttatcag ctgtatcttc cacttcatct
     4861 tttgcttttt ctaacttttg aatatattgt ttcaagcttg agttttcagc agttgcttcg
     4921 tctaatttct tttgtgtatc tgttaactga gtttctacat ttgttttttc ttgtgtcagt
     4981 gttgcgattt gttgattcaa accatttaca gtattttgta attctgaaag ttttgcttgt
     5041 gcttcttgta gtcttgctgt ccaatctgca ttcagatgat tgatttcatc atttttttgg
     5101 ttgatctcat ctagtttgac attgatttca ttttgtttgc tttgtagttg tgcatccttg
     5161 ctgactaatt gactttctaa gttttgtttt tctgctgccg attgattttt ttggttttct
     5221 aattcattta cttttgtttg gtattcttgg acatctgcct ttgaatcttg caatgtctgt
     5281 tctttttgtg ctagtcgagc ggtaagatct gtaatcgctt gctctttatc tgtcaatgta
     5341 tgatcaagct gtgtcagatt ctcattgatt gtatcaatat ctgtctctcc accccacaaa
     5401 ataatttcat ttgcgtaccg cgtgcctgtg tagccaatta gacatagaaa tgcaacgaca
     5461 atcccaccag taataaattt ctttttcatt tgcatagctc cttaatccaa tacttttaca
     5521 tgctaaaagt aagtgatctc aaacacaatg tcaagcgttt ttaaattaca tatgtaattt
     5581 taatataaat actatcaaat actcatttaa tcctcctttt ttatctattt aaaaaatctt
     5641 ttttatagag aaaaatgcag gttaatactt tcttaaataa atatttatgg tgaacaaaaa
     5701 caaaaaagca agttttatta aacgtaaccc ttttcatttc atagattact gtatttatta
     5761 caaaaaacg
//
LOCUS       DAZKKZ010000111         5595 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.116, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000111 DAZKKZ010000000
VERSION     DAZKKZ010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5595)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5595)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5595
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.116"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            6..863
                     /locus_tag="ACG8LA_002762"
     CDS             6..863
                     /locus_tag="ACG8LA_002762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HFQ0205014.1"
                     /translation="MAEIMDNQTGAPEEITKKDVTKAYLRWHFANEIPHSFERYLAPS
                     LLYGMMPILKKLYKDEDSLKAAYKRQLLFFNTQLSWGGGVITGLMSSMEQRRAEEEYE
                     EKEILMQDDLMYNTKAGLMGALAGIGDAIDSGTVQYIFIAIAVPWAQQGSPLGALFPF
                     ICFGLYQVLLGVFFARQAFTMGRNATGLMQNTGVQTAIEMLSVLGLFMMGVLAGNYVK
                     VESSLKFAISGREFVIQEILDQIVPGILPLAVVMGVYLFYTKKGLKVTQALLWLTGIL
                     IVLAGIGIL"
     gene            885..1394
                     /locus_tag="ACG8LA_002763"
     CDS             885..1394
                     /locus_tag="ACG8LA_002763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HFQ0205015.1"
                     /translation="MGVVNLARVDERLIHGQVMVTLSQKSGVNSIFVVDEVVAKDKFM
                     RDLYKNAGSRTGQKTIVITPEKAKFYWDEYQFKEYNCILIAKTVQTIYDLVKHGIPME
                     ELNIGGIAQKNPDTDLLVTKSVYLNKSDAEKLKEMNEQYGVKNIYFQATPSAPKTGLK
                     DVLNKFDLS"
     gene            1431..1832
                     /locus_tag="ACG8LA_002764"
     CDS             1431..1832
                     /locus_tag="ACG8LA_002764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0205016.1"
                     /translation="MKKNELFRDWEFRYRYIYRKRRTKKSKQRFLSALVSDIYSMRTD
                     VTVIAYDTLAYRSKNIYVGDIEKAEKVICTYYDTPVHALGSYFMFDWKDQRKKTIYSI
                     LLSFILLFSLGWWGMMIYNKNPHHVFDLLSV"
     gene            1944..2297
                     /locus_tag="ACG8LA_002765"
     CDS             1944..2297
                     /locus_tag="ACG8LA_002765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0205017.1"
                     /translation="MLEMIRTIDDPSVAYAFVDEGCYGEKGLDSVRSGMKKEAILFYL
                     DSVGADTPLQFSGNYFSNKEQWLKQVDKLKEKNVNYIFSARKKQAQFFYLTKTDLRGK
                     TFNWQNANQIIALFR"
     gene            2331..2774
                     /locus_tag="ACG8LA_002766"
     CDS             2331..2774
                     /locus_tag="ACG8LA_002766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFQ0205018.1"
                     /translation="MLEIMIVTHGKLSEGLKDAAEVIVGTSSHIETMCLESGEDIQTF
                     GEKVKEKLTMINTAEPMLVFVDLISASPYNQALLAVNELTEEKKAATYVIGGVNLPML
                     LEAINHQMLHTPIEEAVEQIVKQGKDNLTVWHASAEEKKLDEDDF"
     gene            2791..3876
                     /gene="uxuA"
                     /locus_tag="ACG8LA_002767"
     CDS             2791..3876
                     /gene="uxuA"
                     /locus_tag="ACG8LA_002767"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008927 - mannonate dehydratase activity
                     [Evidence IEA];
                     GO_process: GO:0006064 - glucuronate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HFQ0205019.1"
                     /translation="MKWGFRWYGEKGDSIPLKYVRQIPGINGIIGTLLTKMPGDVWEI
                     SEIEELKASVESQGLELLGIESVAIHDAIKAGTDERDYYIDNYIRTIKNLSRCGVRLI
                     CYSFKPIFGWAKTDLFNENNDGSYSLLYDQKIVDQMEPGEMYQLIHSQSKGFKLPGWE
                     EERLKKFAQLEKLYEGMTEEELFENLTYFLEKVIPVCEKADVKMAIHPDDPPWELFGF
                     PRVTKNLGDLKKILNAVDSPYNGLTLCTGSLGANPENDLVEIIHEVGSRIHFVHFRNV
                     EFLGERKFKETAHPSTEGSLDMYHIMKALVQEGFDGPIRPDHGRTVWGEVAMPGYGLY
                     DRAMGLTYMQGLYEAISKEKPLGEHYE"
     gene            3869..4582
                     /locus_tag="ACG8LA_002768"
     CDS             3869..4582
                     /locus_tag="ACG8LA_002768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFQ0205020.1"
                     /translation="MNKIKLFIFDMDGLLLETGRLAYRAYVKSAQKYDYEMRKEVYYL
                     LTGQTEMAIREQMGILYGEDVPYIKWREAINQYKEKIVKEDKRVYTKKGAEEILSFAK
                     ERGIHTIVASSNTRVKVEMYLKMENLYALFDQIISGDDVKKGKPEPEIFLKACSKMNI
                     PPSEALVFEDSIAGIEAARRAGILSFLIKDHLIGLPDHNGKHKLKVDVSLYESNKADY
                     EFYDLHQAKRFLESKGLYL"
     gene            complement(4789..4938)
                     /locus_tag="ACG8LA_002769"
     CDS             complement(4789..4938)
                     /locus_tag="ACG8LA_002769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0205021.1"
                     /translation="MTFYNKDIQYRVTLDTDLNLFVVFDKENTNHVATGVTIEQAVQE
                     LKKSA"
     gene            5334..5534
                     /locus_tag="ACG8LA_002770"
     CDS             5334..5534
                     /locus_tag="ACG8LA_002770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HFQ0205022.1"
                     /translation="MNNGTVKWFNADKGFGFITGEDGNDVFAHFSAIQGDGFKTLEEG
                     QAVSYDVEDGQRGPQATNIVKA"
BASE COUNT         1940 a          856 c         1217 g         1582 t
ORIGIN      
        1 gggaaatggc tgaaataatg gataatcaaa caggtgctcc tgaagaaatc acgaaaaaag
       61 atgtaacaaa agcctatctg agatggcatt ttgcaaacga aattcctcac tcttttgaac
      121 gttacttggc gccatcacta ctatacggaa tgatgccaat cttgaaaaaa ctttataaag
      181 atgaagactc tttaaaagca gcatataaac ggcagttact gttcttcaac actcaattaa
      241 gctggggtgg cggtgtgatt actggcctaa tgtcttctat ggaacagcga agagcagaag
      301 aagagtatga agaaaaagag atcttgatgc aggatgactt gatgtataac acgaaagcgg
      361 gattgatggg ggcactagca ggaatcggag atgcaatcga ttcaggaacc gtccaatata
      421 tttttatcgc aatcgcggta ccttgggcac aacagggaag tcctttaggc gcactttttc
      481 cttttatctg ctttgggttg tatcaggttt tactaggggt atttttcgca agacaagctt
      541 tcactatggg ccgtaatgct acaggcctaa tgcaaaacac tggtgttcag acagcgattg
      601 aaatgctatc agttttaggg ttgtttatga tgggggtgct tgcgggaaac tatgtaaaag
      661 tagaatcttc attgaaattt gcgatatccg gacgtgagtt tgttatccag gaaattcttg
      721 atcaaatcgt gccagggata ttacctttag ctgtcgtaat gggtgtgtac ttgttctata
      781 cgaaaaaagg attgaaagtc acacaagcat tattatggct gactggaata ttaattgtgc
      841 tagcaggaat cggtatttta taaaaagaag ggaacgtgaa taagatgggt gtagtcaatt
      901 tagcgcgtgt ggatgagcgt ttgatccatg ggcaagtaat ggtaacgtta tctcaaaaaa
      961 gtggagtgaa ttccattttt gttgtagacg aagttgtagc aaaagataaa tttatgagag
     1021 atctttacaa aaatgcagga agccgtacag gacaaaaaac aattgtcatt acaccagaga
     1081 aagctaaatt ctattgggat gaatatcaat ttaaagaata caattgtatt ttgatcgcaa
     1141 aaacagtcca aacgatttac gacttagtaa aacacggaat ccccatggaa gaattgaata
     1201 ttggagggat tgctcaaaaa aatcctgata cagatctttt agtgacgaaa tctgtttatt
     1261 taaataaatc agatgctgaa aaattgaaag aaatgaatga acaatatggc gtaaagaata
     1321 tttattttca agccactcca tctgcaccta aaacaggatt aaaagatgta ttgaacaagt
     1381 ttgatttgtc ataaacaaat gcttagaaaa aagataaaga gggcgaaaaa atgaagaaga
     1441 acgagctgtt tcgtgattgg gaatttcgtt atcgctatat ttaccgtaag cgccgtacaa
     1501 aaaagagtaa acagcgtttt ctttcagcat tagtatcaga tatttacagt atgagaacag
     1561 atgtgacagt cattgcttac gatacgctag cctaccgatc aaaaaatatt tatgttggag
     1621 atatcgaaaa agcagagaaa gttatctgta cttattacga tacacccgtt catgcattag
     1681 gaagttattt catgtttgat tggaaagacc aaaggaaaaa aacaatctac tctatattat
     1741 tgtccttcat tttgttgttc agtttaggtt ggtggggaat gatgatatat aacaaaaatc
     1801 ctcatcacgt attcgatctg ctatccgtat aaacaggtat cactgtacta gcatttggga
     1861 gctacttttt cttattggga aaagcagctc gcggatggcc tagcagacaa acttttattc
     1921 gaaatacttc atccatatta acgatgctag aaatgatccg tacgattgat gatccgagtg
     1981 tagcgtatgc gtttgttgat gaaggctgtt atggagaaaa gggcttagac agcgtgagat
     2041 cgggtatgaa aaaagaggct attctttttt atctagactc tgttggggca gatacaccgc
     2101 tacagttttc gggaaattat ttttcaaata aagaacagtg gctgaaacaa gttgataagt
     2161 tgaaagaaaa aaacgtcaat tatattttta gtgcaagaaa aaagcaagcg cagttcttct
     2221 atttgaccaa aacagattta cgagggaaaa catttaattg gcaaaatgcc aatcagatta
     2281 ttgctctttt tcgataagta aaaagtgcaa aacaaggagt gagaagacta atgttggaaa
     2341 tcatgatcgt tacacatggt aagttgagcg aaggactgaa agatgcggcg gaagtaattg
     2401 tcgggacatc gagccatatt gaaacaatgt gcttagagtc tggggaggac atccaaacat
     2461 tcggagagaa ggtcaaagaa aaattaacta tgatcaacac agcagaaccc atgctagtat
     2521 ttgttgatct aattagcgca agtccgtaca atcaagcgct cttggcagtc aatgaactga
     2581 ctgaagaaaa gaaagcagcc acttatgtca tagggggcgt gaatctgcca atgttgttag
     2641 aagcaatcaa tcatcagatg cttcacacac cgatagaaga agcggtggaa caaattgtca
     2701 aacaaggaaa agataattta actgtttggc atgcttcagc ggaagaaaaa aaattagatg
     2761 aggacgattt ttagaaggaa ggctgaaaag atgaagtggg gatttagatg gtatggtgaa
     2821 aaaggggatt cgatcccatt aaaatatgtt cgccaaatac cgggaataaa tgggataatt
     2881 ggaactttgc tgactaaaat gcctggagat gtttgggaga tttcagaaat tgaggagttg
     2941 aaagcatctg ttgagagcca aggactggaa ctgcttggaa ttgaaagtgt agcgatccac
     3001 gatgcaatca aggcagggac agatgaacga gattactata ttgataacta tatacgaaca
     3061 atcaaaaact tgtctcgatg tggggttcga ttgatttgtt atagcttcaa accaattttt
     3121 ggatgggcga aaactgattt gtttaatgaa aacaacgatg gaagctattc tcttttatac
     3181 gatcagaaaa tcgtcgatca gatggagcca ggagaaatgt atcaattgat acacagccag
     3241 tcaaagggat tcaaattgcc gggttgggaa gaagaacggt tgaaaaaatt cgctcagctg
     3301 gaaaaactgt atgaaggaat gaccgaagaa gaattatttg aaaatctgac ttatttttta
     3361 gaaaaagtga ttccagtgtg cgaaaaagca gatgtaaaaa tggctatcca tccagatgat
     3421 ccgccatggg aactttttgg ttttcctaga gtgacgaaaa atcttggcga cttgaagaaa
     3481 attctaaatg cagtagattc tccatataat ggactaacgc tgtgcacagg atctttaggg
     3541 gcaaatccgg aaaacgattt agttgaaatc atccatgagg taggttcgcg catccatttt
     3601 gtccacttca gaaacgtgga gtttttagga gaaagaaagt tcaaagaaac ggcacatccc
     3661 tctacagaag gctcccttga tatgtatcat attatgaaag cgttggtgca agaagggttc
     3721 gacggtccta tacgccctga tcatggtaga accgtgtggg gtgaagtggc tatgcctgga
     3781 tatggcctgt atgatcgtgc aatgggactc acttacatgc aaggtctata tgaggcgata
     3841 agtaaggaaa aaccactggg agagcattat gaataaaatc aagctcttca tctttgatat
     3901 ggatggcctt ttattagaaa ctggacgttt agcttatcgt gcttatgtaa aatcagcaca
     3961 aaagtatgat tatgaaatgc gtaaggaagt ctattattta ctaactggcc aaacagaaat
     4021 ggcgataaga gaacaaatgg gcattttgta cggagaagat gttccatata tcaaatggcg
     4081 agaagcaatc aatcaatata aagaaaaaat cgtgaaagaa gataagagag tatatacgaa
     4141 aaaaggagca gaagaaattt tatcttttgc aaaagaaaga ggaatccata caatcgtggc
     4201 ttcgtctaat acacgggtaa aagtagaaat gtatttaaaa atggaaaatc tatatgcctt
     4261 gtttgatcaa atcatttcag gggatgatgt aaaaaaagga aagccggaac cagagatctt
     4321 tttgaaagct tgttcaaaaa tgaatattcc tccaagtgaa gcacttgtat ttgaagactc
     4381 gattgcaggg atcgaagcag caaggcgagc gggcattttg tcttttctca tcaaagatca
     4441 tttgataggg ttgcccgatc ataatgggaa gcataagttg aaagtagatg taagtttata
     4501 tgaatccaat aaagcagact atgaatttta tgacctgcat caagcaaaac gatttttaga
     4561 aagtaaaggg ttgtatctct aataaagagg actattttct agtcctcttt atttattgtc
     4621 ctgcacgact gagggaacag atgaaaaaga agtaattttt tattttgaag tatctacctt
     4681 atttgtagtg aacaatttag aacaaacaca aaacgcatct actgttatct accagtagat
     4741 gcgtttaaag agaagaacga gaatcgtcca tatgagggtt tccactcctt atgcagattt
     4801 ttttaattct tgcactgctt gttcgatcgt aacacctgtc gctacatgat tggtattttc
     4861 tttgtcaaaa acgacaaata gattcaaatc tgtatccaag gttactcgat attgtatatc
     4921 tttgttatag aatgtcatag ccattctcct ttctttaaat acttgctgaa aggcaacgaa
     4981 cgcgttgata acgaaattcc atttataagt ataccaccaa ttgaaaggtt ttcatagtta
     5041 agaaatttta aagtcaaaag ttgcagataa aagcaaataa acaagaaaac aaaaagtgaa
     5101 tcaatcgcgg ttattcaact ttttcttcga ttcgaagaca atagaagaca atgaatttta
     5161 tatttcattg cattatcctt gtgttattag aaaaagcatg atatattaaa tgagtaatct
     5221 attttgaaac gtaatttgag cgatatatct acatagataa aactcctttt gcctatcaaa
     5281 tatttattgc aacgaaaaaa cgtacattga tacgtatcag gaggaattta tttatgaata
     5341 acggtacagt aaaatggttc aacgcagaca aaggttttgg ctttatcact ggtgaagatg
     5401 gaaatgatgt atttgcacat ttttcagcta tccaaggtga cggcttcaaa actttagaag
     5461 aaggccaagc agtgtcttac gatgttgaag atggtcaacg tggccctcaa gcaacaaaca
     5521 ttgttaaagc ttaataaaaa ttgactttta accgtctttt cgaaagaaaa gacggttttt
     5581 ttgtacgaaa aaatt
//
LOCUS       DAZKKZ010000112         5382 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.117, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000112 DAZKKZ010000000
VERSION     DAZKKZ010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5382)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5382)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5382
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.117"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            56..1921
                     /locus_tag="ACG8LA_002771"
     CDS             56..1921
                     /locus_tag="ACG8LA_002771"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HFQ0205023.1"
                     /translation="MDNQAVGRRVWEAVGGQKNVKSLVHCATRLRFRLKDESLADTQK
                     LKEDPDVIQVVQSGGQYQVVIGSNVADVYQSIVDEEGLAVSEDGKEESKNILNRLIDI
                     ISSIFTPFLGAMAAAGVLKGFLSLATVMGWLTADSGTYQILFAAADGVFTFLPVMLAF
                     TAAKKFKANQFLAVAIAMALVYPAITAVAGAGEAISFFGIPVILSPSGYTSSVIPIIL
                     AVWVQSKLEPFVKKVIPQFLQMILVPLVVLVVMVPLTFLALGPIGTVAGNALGGLFNS
                     IYGFSPIVAGLIMGSLWQVFVMFGMHWGFVPIMFLNIEQYGFDVLMPMLLPAILAQGG
                     AALAVALRTKDTKLRALGISSTVTSLFGITEPTVYGVTLPLKKPFIAACISGGIGGAI
                     IGFSGVKAFSSSLVSLLTIPTFINTVDGVESNVTVAVIATGIAFVLAFVGTLILGFDE
                     QTQDNQLENKHANAGEPITSARHTLKSPLTGKVLPLSEVPDQVFSSGVMGKGIAIDPE
                     VGELVAPADGEITTIFPTGHAVGITTTDGAEILIHIGMDTVELNGNGFEILVKQGDLV
                     KAGDLLIRFDIEAIRAAGYSVITPVVITNTDAFADILELDQKEIIANEDVLAIVK"
     gene            1935..3378
                     /locus_tag="ACG8LA_002772"
                     /pseudo
     CDS             1935..3378
                     /locus_tag="ACG8LA_002772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738852.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
     gene            3486..4187
                     /locus_tag="ACG8LA_002773"
     CDS             3486..4187
                     /locus_tag="ACG8LA_002773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFQ0205024.1"
                     /translation="MKRTRVLYLEVADKIKEDIFSGKYPVGSMLPTESELEELFQVSK
                     ITVRKAIELLASDEYVAKKSGRGTTVLSNRPYNRLSKAASFTQILENSRYEVRKETLD
                     LQLVHIKKEDPLFSFFGEQAVCFKRLYYLNNQPYIYFVHYLPQEMMQFSREEFGKESL
                     YRLLTKKGYTIDSFSDDFSAVFLTEEEQGILKTDAQIGIKRIRKSSTQIGEMIEYSEA
                     VYHTELHPYHIDYET"
     gene            4313..4825
                     /locus_tag="ACG8LA_002774"
                     /pseudo
     CDS             4313..4825
                     /locus_tag="ACG8LA_002774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014566402.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
BASE COUNT         1705 a          919 c         1225 g         1533 t
ORIGIN      
        1 tttttttcaa tctgggtttt tattttttaa ataaaaaaga aagaaggaaa aaacaatgga
       61 taatcaagca gttggtcgtc gtgtatggga agcggtagga ggacaaaaga atgtcaaaag
      121 tttagtacat tgtgctacgc ggttgcgatt cagattaaaa gatgaatctt tagcagatac
      181 gcaaaagtta aaagaagacc cggacgtgat ccaagtcgta caaagtggcg gtcagtatca
      241 agtagtgatt ggcagtaatg tagcagatgt ttatcaatcg atcgtggatg aggaaggtct
      301 tgcagtttcg gaggatggaa aagaagagtc caaaaatatt ttgaatcgtc tgatcgatat
      361 tatctctagt atatttacac cttttctagg ggcgatggca gccgccgggg tattgaaagg
      421 attcttatca ttggcaacgg tgatgggctg gctgacagct gatagcggta cttatcaaat
      481 attgtttgct gcagcagatg gtgtctttac cttcttacct gtcatgcttg cttttacagc
      541 agctaaaaag ttcaaagcca accagttttt agcagtagca attgctatgg cacttgtgta
      601 tccagctatc acagcagttg ctggtgcggg agaagctatc agtttctttg ggatcccagt
      661 gattctttca ccatctggtt atacttcttc tgtcatacca atcattctag ccgtatgggt
      721 tcaaagtaaa ttagagccat tcgtaaaaaa agtgattccg caatttctgc aaatgatttt
      781 agttccgctt gtcgttttag tagtgatggt tccattaaca tttcttgctt taggaccaat
      841 cgggacggtt gccggtaatg ctttaggcgg tctcttcaac tcgatttatg gatttagtcc
      901 aatcgtagca ggtctaatca tgggaagttt atggcaagta ttcgtgatgt tcggcatgca
      961 ttggggattc gtaccgatca tgtttttgaa tatcgaacaa tatgggtttg atgtattgat
     1021 gccaatgctt cttccagcca tcttggcaca aggtggggct gctttagctg tagcattgcg
     1081 aacaaaagat acgaaacttc gagcattagg gatttcttct acagtgactt cgttatttgg
     1141 aatcactgaa ccaactgtgt atggtgtgac attacctttg aagaaaccat tcattgccgc
     1201 ttgtatttct ggaggtattg gtggagctat tatcggattt tccggagtaa aagctttctc
     1261 cagcagtttg gtcagcttat tgacgattcc gactttcatt aatacggtgg atggtgtaga
     1321 gtcaaatgtg acagtagcag taatagctac aggaattgct tttgttcttg cattcgtagg
     1381 tacattgatt ttaggatttg acgaacaaac acaagacaat caattagaaa acaaacatgc
     1441 gaatgcagga gaaccgatta cttcagcacg gcatacctta aaaagtcctt taacgggtaa
     1501 agtactgcca ttgagtgaag taccagacca agttttttct tctggcgtga tgggaaaagg
     1561 tatcgctatt gatccagaag taggagaact agttgcacct gcagacggag agatcacgac
     1621 tatttttcca actggacatg ctgtagggat cacaacgact gacggagcgg agattttgat
     1681 tcatatcggg atggatacag tagaattaaa tgggaatggc tttgagatct tagtcaaaca
     1741 aggggatctc gtcaaagcag gagatttatt gattcgtttt gacatcgaag caattagagc
     1801 agctggctat agcgtaatca ctccagttgt cattacgaat actgatgcat ttgccgatat
     1861 acttgaatta gaccaaaaag agattattgc aaacgaagat gttctggcaa ttgtaaaata
     1921 aggaggaaat caggatgcaa tcacgttttt cagaaaaatt tttatggggt ggagcaactg
     1981 ctgccaaatc aattagaagg ggcttatgat cgagacggaa aaggactatc cgttgcagat
     2041 gctatgcctg gaggtaagca gcgctttgcg attatcggca gtgaagaatt tgactggacg
     2101 attgatcaag aaaaatatat ttacccgaat catcgaggaa tcgatcatta cgatcgtttc
     2161 aaagaagatc ttgccttgtt tgcggaaatg ggattcaaat gttatcgttt ttcgattgcc
     2221 tggacacgaa tttttccaaa tggagacgaa ggtactccta acgaagcggg attagaattt
     2281 tatgatcagc tgattgatga gtgcttaaaa tatgatattg aacctgtgat cacgatttct
     2341 cattacgaaa tgcctcttca tttggcaaaa gaatacggtg gctggaaaaa tcgaaaactg
     2401 atcgacttct atgaacgatt tgctcagaca gtattagaga gatacagcag taaagtcaaa
     2461 tattggatga ctttcaatga aatcaattcg gcctttcact ttccagcttt aagtcaagga
     2521 ttagtaaaaa gcaatggagc aggagagtac caaaatattt tccaagcatg gcataatcaa
     2581 ttcgttgcaa gtagcaaagc cgtaaaaatc ggccacgaat tgcgttcgga tatccaaatc
     2641 ggctgcatga ttatctatgc aacaacttac agcatcgatg ccaatccagt caatcaggca
     2701 gcaacaatga tccaaaacca agaattcaat tttttctgca cggatgtcca agtacgtgga
     2761 gaataccctg catacacagc gcgtacccat aaaaaatatg gagtcgatcc ggaaaaatta
     2821 gagcaaacgg aaaaagactt ccagttgcta aaagaatatc cagtggacta catcggattt
     2881 agttattata tgtctacggc aatcaatgag actgatccac aagcagcaac ttcagaaggg
     2941 aacttgctgg gaggagtaaa aaatccgttt cttgaggcaa gtgaatgggg ctggcagatc
     3001 gatccagaag ggctgagaat cgcattgaat gaattataca atcgttacca gaaaccatta
     3061 ttcattgttg aaaacggtct tggagccatt gatcatatgg aagaggatgg cacgattatt
     3121 gatgattatc ggatcgatta tttacgtcgt catatcgaag cgatggctaa tgcagtagca
     3181 gacggtgtag atttgatggg ctatacgcct tggggatgta tcgatcttgt cagtgcatca
     3241 acaggagaaa tgagtaaacg ttacggcttt atctatgtgg atctagacga tgaaggaaat
     3301 gggacactga atcgatcaaa gaaaaaatct tttgattggt ataaagaagt aattgcctca
     3361 aatggcgtaa acttgtaatt aaagcagctg aatgaaaaag aacacacttc tcacatgtga
     3421 tttgtgttct ttttttattt tttatgtgct attcttttag taatagtaaa gcaaagggtg
     3481 acgttatgaa aaggacacgt gtactatact tggaagtcgc agataaaatt aaagaagata
     3541 ttttctcagg aaaatatcca gtcggttcga tgttgccgac agaaagtgaa ttagaagaac
     3601 tgtttcaagt cagcaaaatc actgtccgaa aggcaatcga actgctggca tcagatgaat
     3661 atgtcgcaaa gaaaagtggt cgtgggacga cggttctaag caatcgtcct tacaatcgat
     3721 tatccaaagc ggcaagcttt acgcaaatct tggagaactc ccgatatgaa gtccggaaag
     3781 aaacgctgga tttgcaattg gtccatataa agaaggaaga tcctttgttt tcctttttcg
     3841 gtgagcaagc tgtttgtttt aagcgcttat attatttgaa caatcagcct tatatttatt
     3901 ttgttcatta tcttccacaa gaaatgatgc aattcagcag agaagaattt ggcaaagaat
     3961 ctttgtatcg tttgctgacg aaaaaaggat atactattga ctcattttct gatgatttct
     4021 cggcagtatt tttaacagaa gaagaacaag gaattctgaa aacagacgca cagatcggca
     4081 tcaaacggat acggaaatcg tctacgcaaa ttggggaaat gattgaatat tcggaggcgg
     4141 tctaccatac ggagctgcat ccttaccata ttgattatga aacataaata aaaaaagagg
     4201 ttgtgaaaaa gctgccctgc atcaagtaat aagaacagcc aaacaaaaat agcttctcat
     4261 atttttcgtt tggttaggct tattaccgca gatacacggc tgtttctgga ttaccattta
     4321 ttctggataa gggggtgtgg cacgattttc agaaggaatc tatgaaccaa tcactgtatt
     4381 gattttagct tcgatggtaa ccccattcgg cttgacgatc gcttatttct tagggaaaat
     4441 cattcgtaaa aatatactca atcgtcaaga aatcgataca ttgaagaccg cttttcctat
     4501 ggggatctgt cagatcacag agggatgttt ccctatcgta ttgaacgact tggcacgcaa
     4561 tgtcatagca acgggagtcg gtgggacagt aggtggcgga ttaagcatgt tttggggcgc
     4621 agatagccgt attccggcat cgggaatgtt tgcagtcgct acgatgacca gaccatgggc
     4681 attcattggt gcattgttag ctggttcttt tgtcacagga ataaccattt tattattgaa
     4741 aaaaccagta gatccgaatg cagaaatcat ccaagaagaa aaagaggaag aagacatatc
     4801 ttgggatgat ttgacaatta gttaggagag gcagaatgga ttacaagaaa aaagtacaat
     4861 agatgtacct tgagacagga atggtatgaa agaatcagag ttagaaagaa tcgaatatac
     4921 agattttggt ttaggagcga tcgaaactgt ccagagcatc ggcaccctcc ttgaaatgac
     4981 gatgaaggaa aaatgagaac ctttcgttgt cgaaagggtc tggtatacct tatgtcgaag
     5041 gaaaggaaac aaaaaaactt tcctgtacta ttccaaaaag gaaagaaagt tattatacag
     5101 taaaaaaaga aattattctt catgctagag atcagtacac gttcgagccc aatatcaaac
     5161 actagttcca ggcaggcgca acaggtgcgg ttatcactga attttcttcc agcagtgacg
     5221 attcaagtga tatttttaca aatccagcta tttatcgtta acaaaaagat ttttaggaga
     5281 agctgatgaa caaaaatgat caaattttga tcgtttagtt cgtcggcttt tttatttaga
     5341 gaaacatcat ttatcagtga aacataacac gagaacaaaa tg
//
LOCUS       DAZKKZ010000113         5336 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.118, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000113 DAZKKZ010000000
VERSION     DAZKKZ010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5336)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5336)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5336
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.118"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(86..1225)
                     /locus_tag="ACG8LA_002775"
     CDS             complement(86..1225)
                     /locus_tag="ACG8LA_002775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HFQ0205025.1"
                     /translation="MQSRFKQSKLFFWTVELVLTIIGVYFILQMPNIFSPILKMLSAI
                     FLPLLVAGFIYYMFDPIVVFLEKHRIPRVFGFLLTFLVVIILVVLTVMNVVPQLMEQT
                     IQLTQSLPMYADETSKWLNELAQREEFKNFNLEEQLASANLSLSNLFNIILVSLSASV
                     SKIISFMMQFFILLFTVPFILLFMFKDGHKFIDALSHFFPKAIRKELRQTVKELNETL
                     SAYISSTILDALIIGVMSFLAMRIFDQPYSLLLAVICGITNIIPYVGPFIGAVPAIIV
                     GLFISPFQALYMALSILVIQQLDGNLIKPLLFGKSMNIHPLTIILVLIGAGSVAGILG
                     MLICIPVYAVIKTIILNIRKIYLLRRMEHVSEKLDSPKVLEETSE"
     gene            complement(1534..2247)
                     /locus_tag="ACG8LA_002776"
     CDS             complement(1534..2247)
                     /locus_tag="ACG8LA_002776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HFQ0205026.1"
                     /translation="MNDMVLTIPEIILRLGIAMLFGGAIGFERQYKNRPAGMRTHILV
                     CMGACIIALIQVEIASGALRDALEYPQLAGTIRSDEARLIAQVVSGVGFLGAGTIIVT
                     KQSVTGLTTAASLWAIAGLGIAIGMGYYSIAIISFIGIAIALTVVKRVIHVPTTKKLE
                     IQFIHRKETKDFLTDYFEEKNIVIEDVNFDVKFVDDYRVYKNIYTIDLPKGLTYADVI
                     EELSVHKNITKLHLVSIAQ"
     gene            complement(2501..3202)
                     /gene="nagB"
                     /locus_tag="ACG8LA_002777"
     CDS             complement(2501..3202)
                     /gene="nagB"
                     /locus_tag="ACG8LA_002777"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004342 - glucosamine-6-phosphate
                     deaminase activity [Evidence IEA];
                     GO_process: GO:0006044 - N-acetylglucosamine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HFQ0205027.1"
                     /translation="MEIIRVKNAEEGGKKAFEIIKEGMNKGAKVLGLATGSTPVTLYK
                     EMTSSDLDFSEMTSVNLDEYVGLGGSDEQSYRHFMDVQLFDKKPFKETFVPDGKAEDL
                     EAACKKYDQIIDAHPIDIQILGIGQNGHIGFNEPGASFDGTTSVVDLTESTINANKRF
                     FDKAEDVPTKAVSMGIGSIMKSKEIVLMAFGESKADAIKGMIEGPVTNHLPASVLQNH
                     DNVVVIIDEEAASKL"
     gene            3436..4968
                     /locus_tag="ACG8LA_002778"
     CDS             3436..4968
                     /locus_tag="ACG8LA_002778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HFQ0205028.1"
                     /translation="MSILTLNNITQQFGDKILYEGVDLQLNAGEHLGLIGQNGAGKST
                     LIKIITGEILPDDGQIHWQKNIHKGYLDQYVEVDETLTIEEFLKTAYAKEYEKEEKIA
                     FLYQTYSETFDDSLLEKAGKLQTELDQGVFYQIDTLVAEMSSGLGIDVLGLDSLLKNL
                     SGGQRSKVILAKLLLENPDVLILDEPTNHLDDQHIQWLTQFLQDFDGAYIVISHDQEF
                     LDQITTHIADIEFGKITKYTGHLKQALKQKEQNRESYLRQYHAQQKQIEKTEAYIRKY
                     KAGSRSTMAKSRQKQLDKIERLTPPASASKAVFDFPFSPIVTTLAVETTDLVIGYDRP
                     LLAPINLTIRFGENIAIRGFNGIGKSTLLKTLIGEIEKISGDFHFPDNTKINYFSQDL
                     YWENPLETPLQYLSSQFPKATIKELRRQLAKAGLVNQLASEPLTTLSGGEQTKVKLAQ
                     LTMNQGNLLILDEPTNHIDQETKESLQDGIQKFPGTVIIVSHEQEFYQDLVQRVIEIE
                     PK"
     gene            complement(5159..>5336)
                     /locus_tag="ACG8LA_002779"
     CDS             complement(5159..>5336)
                     /locus_tag="ACG8LA_002779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFQ0205029.1"
                     /translation="VFMFMYFIGGAAGSLLGTTMWQQYGWLGVTVSGLVFQGCAFFFQ
                     TVVFKGKRNLENKK"
BASE COUNT         1757 a         1082 c          893 g         1604 t
ORIGIN      
        1 tttattttaa ttcaaaaatt tttcgaaaaa taaaaagagt ttagcgtaca gatattttaa
       61 atgtacactg aactcttttt tatgcttatt cacttgtttc ttccagcact tttggactgt
      121 ctaacttttc cgaaacatgt tccattcttc tcaataaata gattttccgg atatttaata
      181 ttatcgtctt aatcactgca tagacaggta tgcaaatcag catgcctaat attcctgcga
      241 cacttcctgc tccaatcaat accaagatga tcgtcaaagg atggatattc attgatttcc
      301 caaataacaa cggcttgatc aaatttccat ctaattgttg gatcactaaa atcgacaacg
      361 ccatatacaa agcttgaaat ggagagataa acaaaccgac aatgattgct ggtaccgctc
      421 caataaaagg gccgacatac gggataatat tcgtgattcc gcaaatgacc gcaagcaaca
      481 agctataagg ctgatcgaat attctcattg ccaaaaagct cattacacca ataatcaaag
      541 catctaagat cgtactgctg atataggcag ataatgtttc gtttaattct tttaccgttt
      601 ggcgtaactc tttacgaatc gctttcggaa agaagtgaga caacgcatca ataaatttgt
      661 gcccatcctt gaacataaat agcaaaataa atggaacggt aaataacaaa ataaaaaatt
      721 gcatcataaa tgaaatgatt tttgagacac ttgcagataa actgactaat atgatattga
      781 acaaattact aagagataaa tttgctgatg ctaattgttc ttccaaattg aaatttttaa
      841 actcttcccg ctgcgccaat tcatttaacc atttgcttgt ttcatctgca tacattggca
      901 agctctgggt caattgaatt gtctgttcca ttaactgagg cactacattc atgacagtta
      961 aaacaactaa aatgattacg accaaaaacg tcaataaaaa accgaacact ctcgggatcc
     1021 gatgcttttc gagaaaaaca acgattggat cgaacatata atagataaaa ccagcaacaa
     1081 gcaatggtaa aaaaattgcc gaaagcattt tcaatattgg actaaaaata ttcggcattt
     1141 gtaaaataaa gtacacgccg atgatcgtga gtactagctc cactgtccag aaaaataatt
     1201 ttgattgttt aaaacgtgat tgcatacatc tcctccaagg tcctttgata cttctattct
     1261 atcatttaac aaagagttac gcgctgagat tttcatttgc ttaaaaaaaa caaaaaaaat
     1321 aaacatattt taatgagtag acgagtactt aaacaaaaac acggtttgga gtagtgacaa
     1381 aaattatact gcagtccctt tttccaaata aacggtgttc aaaagcttgc atcttcgtaa
     1441 taagcccagc caaacgaaaa atataaggaa ctatttttat ttggctgggc ttattacttg
     1501 atgtaggaca tctattttac aacctcagat catttattgc gcaatactga ctaaatgcaa
     1561 ctttgtgata tttttgtgta cggacaactc ctcgatcaca tcggcataag tgagcccttt
     1621 tggaagatca atcgtataga tatttttgta cactcggtag tcatcaacga attttacgtc
     1681 aaaattcaca tcttcgatta cgatattttt ctcttcaaaa taatcggtaa gaaaatcttt
     1741 ggtttctttt ctatggataa attggatttc taacttttta gtcgtaggta catggatcac
     1801 gcgtttcact actgtgagtg caatagcaat cccgataaaa ctgatgatcg caatggaata
     1861 gtaacccatg ccgatggcga tccctaatcc agcaattgcc cataaagaag cggcagtcgt
     1921 aagtcccgtc accgattgtt tcgtgacgat gatcgttccc gcgcctaaga aaccgacacc
     1981 actcaccact tgagcaatca gccttgcttc atctgaacga atcgttccag caagctgtgg
     2041 atactctaaa gcatctctta atgcaccact agcgatctca acttggatca atgcaatgat
     2101 acatgctccc atacaaacta aaatatgcgt acgcatacct gctggacgat ttttatattg
     2161 tcgttcaaaa ccgattgctc cgccaaatag catagcgatc cctaaacgta aaataatctc
     2221 tggaattgtc aataccatat cattcatcta aacaccctcc agtccaatat atcatgtctg
     2281 aaaggagcag acaaaaaaag tgcaattttt acctcttacg aaaaaaggac tgtgacaaaa
     2341 tttttgtcat agtccttttt atgaataaac ggtgttcaat cagctgaccc tcggtattac
     2401 tcaacaaacg gcaaaatatg gggagctatt tttcctttgt cttctctaat actcaggtca
     2461 aaacgctgat ttcacaacct ctttagccta ctattgaaaa ttacaactta cttgctgctt
     2521 cttcatcgat gatcacaaca acattgtcgt gattttgcaa tacacttgct ggcaaatgat
     2581 tcgttacagg tccttcaatc atccctttga ttgcatcagc tttgctttcg ccaaatgcca
     2641 tcaagacgat ttctttactt ttcataattg aaccgattcc cattgaaaca gcttttgttg
     2701 gtacatcttc tgctttatcg aagaatcgtt tgtttgcatt gattgttgat tctgttaagt
     2761 caactactga agtcgttccg tcaaatgaag caccaggttc attgaaaccg atatgtccat
     2821 tttgcccgat tcctaagatt tggatatcga ttggatgtgc atcgatgatt tgatcatact
     2881 ttttgcatgc tgcttccaga tcttctgctt ttccatctgg tacaaacgtt tctttgaatg
     2941 gttttttatc aaataattgg acatccatga aatgacggta gctttgttca tctgaaccgc
     3001 ctagtccaac gtactcatct aagtttacag aagtcatttc actgaaatcc aaatcgcttg
     3061 aagtcatttc tttatataaa gtaactggtg tgcttcctgt tgccaatcct aatacttttg
     3121 cacctttgtt cataccttct ttgatgattt caaatgcttt ttttccgcct tcttcagcgt
     3181 tttttacacg aatgatttcc atagtgattg ctcctttata ttttggtata gcccaattat
     3241 agcattcttt ttttcttttt acaataatta gtatagacca aattgcattt ttttcatttt
     3301 cttgacaata aataggaatc cgtgttaggt ttcataagat ggttcaatca aacaatccat
     3361 gttgcatgaa aaccaagcaa gtgattcact gtggacgctt tatgtctgca gtttttttat
     3421 gaaaaaggag ttattatgag tatactgaca ttaaacaaca ttacccagca atttggcgac
     3481 aaaatcctct atgaaggtgt cgatctgcaa ttaaatgctg gcgaacatct tgggctgatt
     3541 ggacaaaacg gagccggtaa aagtacattg attaaaatca tcactggtga gatcttacca
     3601 gatgacggac agatccattg gcaaaaaaat attcacaaag gttacctcga tcaatatgtg
     3661 gaagtcgatg aaacattaac aatcgaagaa tttctaaaaa ctgcgtacgc aaaagaatac
     3721 gaaaaggaag aaaaaattgc ttttctttac caaacatata gcgagacctt cgatgattcc
     3781 ttgctggaaa aagctgggaa actccaaacg gaattagacc aaggagtgtt ttatcaaatc
     3841 gacaccttag ttgctgagat gagcagcggg ttggggatcg atgtcttagg tttagattca
     3901 ctgttgaaaa atctaagtgg tggacaacgt tcaaaggtga ttttagcaaa actactttta
     3961 gaaaacccag atgttctgat cttagatgaa ccaaccaatc acttagatga tcagcatatc
     4021 caatggctga cgcagtttct tcaggatttt gacggtgcgt atatcgtgat ttcccatgac
     4081 caagaatttc ttgatcagat caccacccat atcgcagaca tcgagtttgg aaagattact
     4141 aagtatactg gccatctaaa acaagcattg aaacaaaagg aacaaaatcg cgaaagctat
     4201 ttgcgccaat atcatgctca acaaaaacaa atcgaaaaga ccgaagctta tattcgaaaa
     4261 tacaaagccg gttcccgatc aacgatggca aaaagccgac aaaaacaatt agataaaatc
     4321 gaacggctga cgcctccagc ttcagcaagt aaagctgtct ttgattttcc attctcgcct
     4381 attgtcacga cattagcagt ggaaacaact gatttagtca tcggatatga tcgaccgcta
     4441 cttgcaccca tcaatttgac catccgcttt ggtgaaaata ttgccattcg aggcttcaac
     4501 gggattggaa aatctacttt attaaaaaca ctgatcggtg agattgaaaa aataagtggc
     4561 gatttccact tcccagataa cacaaaaatc aattactttt cacaagatct gtactgggaa
     4621 aatccattag aaacaccact acaatattta agcagtcaat ttccaaaagc gactatcaaa
     4681 gaattacgtc gccaactagc taaagcaggg ttagttaatc aattagcaag tgaacctctc
     4741 actacattaa gtggtgggga acaaactaag gtgaaacttg cacagttgac aatgaaccaa
     4801 ggtaatttac tgattctcga tgaaccgacg aaccatatcg atcaagaaac gaaagaaagc
     4861 ttacaagacg ggatacagaa atttccagga acagtaatca tcgtctctca tgaacaagaa
     4921 ttttatcaag atcttgtgca acgagtcatt gagattgaac caaaataaac gtttgattga
     4981 atagttgaaa aaaaggagct gtgacaaaag ttttgtcaca actccttctt ctgaataaat
     5041 ggtggccaat tagctgacct tcggtattag ctcaaaaaac ggcaaaatat gaggagctat
     5101 ttttatttgg ctattcttat tacttgatgc agaacagctt ttcacaacct cttttcgtct
     5161 attttttatt ttcgagattt ctctttcctt taaaaacaac tgtttgaaag aagaacgcac
     5221 atccttgaaa aacaagcccg ctaaccgtta cacctaacca gccatactgc tgccacattg
     5281 tcgtccctag caatgaacca gccgcacctc caataaagta cataaacata aataca
//
LOCUS       DAZKKZ010000114         5335 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.119, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000114 DAZKKZ010000000
VERSION     DAZKKZ010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5335)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5335)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5335
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.119"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(15..410)
                     /locus_tag="ACG8LA_002780"
     CDS             complement(15..410)
                     /locus_tag="ACG8LA_002780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0205030.1"
                     /translation="MKNKGQIWYIGYIVSLFLIVTILVTDFPKMVDIGLAILFSAVFG
                     VSHVQILHDKMIKNDADYKINVMDERNIIIKEKAGNITNMFNTILLGVATVIFICLDY
                     IIPAIIVGSIIAIQPIILIIISSVLEKKM"
     gene            complement(400..612)
                     /locus_tag="ACG8LA_002781"
     CDS             complement(400..612)
                     /locus_tag="ACG8LA_002781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFQ0205031.1"
                     /translation="MKNRLEELRKQRGIKQEDLASALEVSRQTIGSLENGRYNPSIIL
                     AFKIARYFQMSIEEIFIYEEESEDEK"
     gene            1684..2286
                     /locus_tag="ACG8LA_002782"
     CDS             1684..2286
                     /locus_tag="ACG8LA_002782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbiJ-NTD4 domain-containing protein"
                     /protein_id="HFQ0205032.1"
                     /translation="MEDIILRDRLTDPLKNSLANVIYDILREADKVYSNYNGKVSWVI
                     YSFLIKEFFKEQINNSYELGYHFTVYYEDIIKRLEDLEWYAYYDLLEVFASAKILDKK
                     KREEVNKILESENSGYRLSESNEFIPITDDISIKSINAVSESPFNYAKNHIHKSLTYI
                     SEKENQDYNTVVREAISAVESCLIEFSGLPANKKILWELL"
     gene            2641..2877
                     /locus_tag="ACG8LA_002783"
     CDS             2641..2877
                     /locus_tag="ACG8LA_002783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB/MazE/SpoVT family DNA-binding
                     domain-containing protein"
                     /protein_id="HFQ0205033.1"
                     /translation="MNIKKRKIREVGNSIVVTLSKESLLQKGLKPGDTIFIDEDKMME
                     AIVKEESKIDLEIDMYVNQALSEYDAAFKELVEK"
     gene            2874..3287
                     /locus_tag="ACG8LA_002784"
     CDS             2874..3287
                     /locus_tag="ACG8LA_002784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HFQ0205034.1"
                     /translation="MIYLSEKDIVKLNVIQIKKYSPRETIGVIDKNALSMAVNQPKQH
                     IFGKDLYPDKFSKAAVLLINLIKKHPFHNANKRTAFLAAYVFLKLNGYSLKMKNQEVV
                     EFVVEIATYQGDFDDLKEATTDILKKNSTKTDSKK"
     gene            3830..4756
                     /locus_tag="ACG8LA_002785"
     CDS             3830..4756
                     /locus_tag="ACG8LA_002785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003953 - NAD+ nucleosidase activity
                     [Evidence IEA];
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="toll/interleukin-1 receptor domain-containing
                     protein"
                     /protein_id="HFQ0205035.1"
                     /translation="MTGRNPKVFISYSWENKENKEWARELADKLLENGIDAYIDQYDL
                     SLGDRLPQFMEQQISDSDYVLIICTPEYKKKANNRTSGVGYEGHIISAELLSGKNERK
                     FIPIIKEGRASEVLPTFLAGKLGIDLSDSQHYDENLDDLITTIFGVKRKPALGDIPRH
                     IKGSPLLPIEHNENKDIEILGIITDKVTVPKMDGSRGSALYKIPFRLNRVPSQLWKEL
                     FVRNWNSPPRYTTMHRPGIASVVDDEILLNGTTIEEVREYHRETLKLCIEKSNTQEKK
                     ILLEEEQKKERENERVRSHKESVQKLADELEF"
     gene            complement(4753..>5335)
                     /locus_tag="ACG8LA_002786"
     CDS             complement(4753..>5335)
                     /locus_tag="ACG8LA_002786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFQ0205036.1"
                     /translation="SIDQNEQRQIEEMRKFGAEKIFIEKQSGATITHRPIFQEVLDFV
                     RDQDIFIVEAIDRLGRNYDEIIDSVNYLKKKNVRLIITNLPIMAEAIGNPLLDKFIKD
                     LIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSANTKDPQRRLVYRSIV
                     QDQENGVAISKIATDYNVTRQTVYRIKKELTIN"
BASE COUNT         1907 a          760 c          902 g         1766 t
ORIGIN      
        1 atgaaccttt atttctacat ttttttctca agcacactac tgataatgat taaaataatc
       61 ggctggattg caatgatact tccgacaata atagctggaa tgatgtagtc taaacaaata
      121 aatataactg ttgccacccc taacagtatt gtgttaaaca tatttgttat atttcccgct
      181 ttttctttga ttatgatatt ccgttcgtcc ataacattga ttttgtagtc tgcatcattt
      241 ttaatcattt tatcatgcaa aatttgaaca tgagaaacgc caaaaacggc actgaataaa
      301 atagcaagtc caatatctac cattttagga aaatctgtaa ccaaaattgt cacaatcaaa
      361 aacaacgaaa caatataacc gatataccaa atctgaccct tatttttcat cttcactttc
      421 ctcctcatag ataaaaattt cttcaatgct catttgaaag taccttgcaa ttttaaatgc
      481 caatataata gagggattat aacgtccatt ttctaaagaa cctattgttt gacgagatac
      541 ttcaagagca gaagctaaat cttcttgttt aattcctctt tgttttcgta attcttccaa
      601 acgatttttc acaacatgct cctttctaaa aaatggaaag tttactttcc tttcgtgctt
      661 ttataatact cctgcgagca caaaatgtca aggaagcttt ccatataaat tttgatttta
      721 atgttttagt tactgttttt atgacacatg aacacactta ttcttatttc ctcttatctg
      781 ctatcaacag aaaagaaaaa gccctgtcaa gagccgatta gatcaagcca gtcgagaaac
      841 gatgttagac caaattgatt ttgggtaatg aatgtttaga acttagtagt catccaaaaa
      901 cgactacttt ttttgttgaa tcgtccaagg acgattcgat gcttttgact tgtaagaaca
      961 ggattgaatg aaaccatact gttcgcatat ttttagtgga tgaacaaaca aaatacgaga
     1021 gattttttgt tcgttcatcc atggttttag aaaaaagagg gacgattttg gaagaagaaa
     1081 atcgtctctt ttttttcttc tttttgtatg acaaaaagaa agatcttttg cccattttat
     1141 ttttataaaa tgggtaggtg gcgttcgcgt aaagcaaatc gatacaatcc aatggttttg
     1201 gcgaatcaga tttaccattc taggcttgtt taatacagac atcgattgtt attttgagaa
     1261 tttatatcct tattggcaat gaaatggata ttctccatac caatagaaat cttcaagata
     1321 attttcggaa atatataaga gttaatcaat tatgatcata tagtaggtaa aaattaggac
     1381 agccttcaat tatatgggaa accaatataa tcaagtaatt attcgggtaa cacaaatact
     1441 agagtactca tttcttataa ctgttttaca cctattaggg atcagtatta ttaatagatc
     1501 tagataaatt aatacgtaat tatataataa tttatgtttg tgccattaaa caatcttaac
     1561 agatatttca ttttatttat gtaaaacaac acgaataatt attgcttcgt aaagttatat
     1621 gagtataagt taatttactg gaggtagtgc aatgcttttt tctgaaagat ttggttttaa
     1681 aaaatggagg atatcatact gagagataga ttgacagacc ctcttaaaaa tagtttagca
     1741 aatgtgattt atgatatatt acgagaggct gataaagttt atagtaatta taatggaaaa
     1801 gtctcatggg taatatattc ttttttaatt aaagagtttt ttaaagaaca gataaataat
     1861 agctatgagt tgggttatca ttttactgtt tattatgaag atattatcaa gaggttagaa
     1921 gacttggagt ggtatgctta ttatgattta ttagaggttt ttgcaagtgc taaaatcttg
     1981 gataaaaaga aaagagagga agtaaataaa attctggagt cggaaaattc tggttacaga
     2041 ttaagcgaaa gcaatgaatt tattccaatc acagatgata tttctattaa gtctataaat
     2101 gctgtatctg aatcaccatt taattacgca aaaaatcata tccataaatc tcttacatat
     2161 ataagcgaga aggaaaatca agattataat actgtagtga gagaagcaat tagtgctgtc
     2221 gaaagttgtc ttatcgaatt ttcaggatta ccagctaata aaaaaatact ttgggaactg
     2281 ctataaaagc aattaaagac aaatcgaata acaatgtcga tcttacattt ttaaaaccat
     2341 ttgagacaat gtatggtttg gcgagtaata atggaatacg acatgcagaa aatgaaaaaa
     2401 caattgtctc agatttacct gatgcagttt tggtgttaac aacatgttca gccgtaatta
     2461 attatttggg agtaaaaata gcatatgact ccaataaatc atgaaaagtt aaaattcatc
     2521 caagagctac attataacta ttaatttcca actctttaaa agtttagtaa ttgaaggaag
     2581 taataagggt gattgaacaa tacggatata cggtgtatac ttatcgtagg agttgatgat
     2641 atgaatatta aaaaacgcaa aatcagagaa gtaggtaatt caatagttgt aactttgtca
     2701 aaagagagtt tattgcaaaa aggtttgaaa cctggagata ctatttttat tgatgaagat
     2761 aaaatgatgg aagctattgt aaaagaggaa agcaagatag atcttgaaat tgatatgtat
     2821 gttaaccaag ctttatctga gtatgatgca gctttcaagg aattagttga aaaatgatct
     2881 atctaagtga aaaagatatt gtaaaattga atgttattca aataaagaaa tattcaccgc
     2941 gagaaacaat cggagtcatt gacaaaaatg cgctgagtat ggctgtaaat caacctaaac
     3001 agcatatttt tggaaaagat ctgtatcctg ataaatttag caaagcagct gttctgctaa
     3061 taaatctgat caaaaagcat ccatttcata atgctaacaa acgtacagca tttttagccg
     3121 cgtatgtttt tctcaagcta aatggctatt cactaaaaat gaaaaatcag gaagtagtag
     3181 aatttgtagt tgaaattgct acgtatcagg gtgattttga tgacttaaaa gaggcaacaa
     3241 cagatatact aaaaaagaat tcaacaaaga ccgattcaaa aaagtagaag caaactaggg
     3301 attcagttaa atctgaagat ttagtttgtt ctttatttta gtttacataa gatacattat
     3361 gcgaagttca ttattttaaa agcttaaata ataaactttt ttataatacc aatttattta
     3421 tgtaaaccaa tgaccttaat cgcttaagca agcatgttat gtaatactct actctctcca
     3481 aaactaatga ctatctattt tcaaagaagc tagaatgatt atctgatcaa atgataattt
     3541 atatttaatt cctggtctac tgctcttctt ttaatcaatt aatgtctaac gtactgtaca
     3601 cgataaagta ggaagactta ttttcaactt cggattcatt tttttaattc ggtgaaaatc
     3661 actaaattaa gagtttatcc aagttcattt tagctgagaa tacgcttgaa aataattttg
     3721 atgaattttc ctgaattaaa atttattgac ttgttgagtg atataattgt aatgtattac
     3781 caaatagtta gcacttagat tagtgatgga aaggaatagt gagaacaaga tgactggtag
     3841 aaatcccaaa gtatttatat catattcatg ggagaataag gaaaataaag aatgggctag
     3901 agaactagca gacaaattac ttgaaaacgg tattgatgca tatatagatc agtatgattt
     3961 aagtttaggt gatagattac ctcagtttat ggagcagcaa atatccgatt cagattatgt
     4021 tctaattata tgtacaccag agtataaaaa aaaggcaaat aatcgtacaa gtggtgttgg
     4081 gtatgaaggt catattatct cagcagaatt gctttctgga aaaaatgaac gtaaatttat
     4141 cccaataatt aaagaaggac gtgcaagcga agtacttcct acttttcttg ctggaaagct
     4201 tggaattgat ttatcagata gccagcatta tgatgaaaac ttagatgatt taattacaac
     4261 tatatttggt gttaagagaa aaccagcatt aggtgatata cctaggcata ttaaaggcag
     4321 tcctttacta cctatagaac ataatgaaaa taaagatatt gaaatcttag gaattatcac
     4381 tgataaagta actgtaccta aaatggatgg ctcaaggggt tctgcattat ataaaattcc
     4441 atttagatta aatagagtac caagtcagct ttggaaagag ttgtttgtta gaaattggaa
     4501 ttcaccacca cgatatacaa caatgcatag accaggaatt gcttctgttg tagacgatga
     4561 aattttactt aatggaacaa ctattgagga agtccgggaa tatcatcggg aaactttaaa
     4621 actttgcatt gaaaaaagta atactcaaga aaaaaaaata ttgctagagg aggaacaaaa
     4681 aaaagagaga gagaatgagc gagtcagatc acataaagaa agtgttcaga aattagcaga
     4741 tgaattagag ttctagttga tagtcagttc tttcttaatt cgatacacag tttgtctagt
     4801 tacattatag tctgttgcta tttttgaaat agcaacacca ttctcctggt cctgaacgat
     4861 gcttctataa acaaggcgac gttgaggatc ttttgtgttc gcactgtata acttaggacg
     4921 tcctttatag acgccgtttg ctttagcaat ctttatccct tgtgcctggc gtcgttttga
     4981 ttcagtacgc tcttgttcag caatcatggc caagatttga atgattaggt ctttgataaa
     5041 tttatccagg agaggatttc cgattgcttc agccatgatc ggtaaattag tgataataag
     5101 tcgcacattt ttcttcttta gataatttac tgaatcgata atctcgtcat aattacgtcc
     5161 aagtcgatcg atagcctcta caataaaaat atcttggtct ctaacaaaat ctagaacttc
     5221 ctgaaaaatc ggtcgatgag taatagtcgc tccagattgt ttctcgatga aaattttttc
     5281 agcaccaaat tttctcattt cctcgatttg acgttgttca ttttgatcga tcgat
//
LOCUS       DAZKKZ010000115         5311 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.120, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000115 DAZKKZ010000000
VERSION     DAZKKZ010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5311)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5311)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5311
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.120"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(73..1221)
                     /gene="nagA"
                     /locus_tag="ACG8LA_002787"
     CDS             complement(73..1221)
                     /gene="nagA"
                     /locus_tag="ACG8LA_002787"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008448 - N-acetylglucosamine-6-phosphate
                     deacetylase activity [Evidence IEA];
                     GO_process: GO:0006044 - N-acetylglucosamine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HFQ0205037.1"
                     /translation="MRTFIYADKFFLASGVKHAGYLEITDGLFGEYTKELPEGEVNII
                     DQSGKWIAPGLVDTHIHGYMNHDVMDNDAEGIKVMSEGLLSCGVTSFLPTTLTSSKER
                     LKDVAETIGKMYQEAPGAKIKGIYFEGPFFTEEHKGAQNPSYFGDPDLDTFHEWQEAS
                     GGLIKKIALAPERQGVEEFVKQVTEEGVVVSLGHSNATLEEAQKAVEAGASVFVHAFN
                     GMRGLNHREPGMVGALLSLEHVFSELICDGHHVHPNAAGILMEKAGHDHVALITDCMM
                     AGGMPDGNYNLGEFPVVVKEGTARLESGNLAGSILKLKEAIKNVVDWGLATPEQAVMM
                     ASLIPAISCKIDDTCGKIAQGRDADFIVLNPDMTLEATYLDGVERFHA"
     gene            complement(1297..2133)
                     /locus_tag="ACG8LA_002788"
     CDS             complement(1297..2133)
                     /locus_tag="ACG8LA_002788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0205038.1"
                     /translation="METLIESFGTIIKEIRKEQKMTQKMLSHDICSQSVLSRIENNEE
                     LPNVLVMMQICQRLGVTIDHVMNLSRKTTRTNDKLFELLDSCFQKRDYRKLEQVLKSS
                     DISENLYQATDFQRYYYYLGVCEFTLRQNISQSLYYLKEALSYSSQKERIHVSDTEIQ
                     LISCIGKIYGVAGKTAEARYYLSRSIQLLHQSADERSKSEFSQIFYNYGNFLFHQNEI
                     DEALEQVNQGIYWAQEKNSYYYLNDLFVLKSLIYKRKEEPERAAFYEGLAQAVKQISK
                     NL"
     gene            complement(2317..3534)
                     /locus_tag="ACG8LA_002789"
     CDS             complement(2317..3534)
                     /locus_tag="ACG8LA_002789"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HFQ0205039.1"
                     /translation="MREFEKSNKLEGVSYDVRGPVLEEAERMQEEGISILKLNTGNPA
                     PFGFEAPNEVIRDLIMNARDSEGYSDSKGIFSARKAIEQYCQLKHFPNVTINDIYTGN
                     GVSELITMCMQGLLDNGDEVLVPMPDYPLWTASIALAGGTPVHYICDEEAEWYPDIDD
                     IKSKITSRTKAIVIINPNNPTGALYPKELLEEIVEVARQNNLIIYSDEIYDRLVMDGL
                     EHIPIATLAPDLFVVTLNGLSKSHRVAGFRVGWMVLSGDKSHVKGYIEGLNMLSSMRL
                     CSNVLSQQIIQTALGGYQSVDELLLPGGRIYEQREYIYNAINDIPGLSAVKPKAAFYI
                     FPKIDTKRFNILDDEKFVLDFLHEHHILLVHGGGFNWNQPDHFRIVYLPKMDDLKQTA
                     KKMREFLATYRQK"
     gene            complement(3683..3844)
                     /locus_tag="ACG8LA_002790"
     CDS             complement(3683..3844)
                     /locus_tag="ACG8LA_002790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0205040.1"
                     /translation="MEKYDGEFSGLGMILGVLIGLAFGRFLLGFMLGIICGIAMDWAA
                     NLWNDYHDN"
     gene            3917..4000
                     /locus_tag="ACG8LA_002791"
     tRNA            3917..4000
                     /locus_tag="ACG8LA_002791"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3951..3953,aa:Leu,seq:gag)
     gene            complement(4240..5311)
                     /locus_tag="ACG8LA_002792"
                     /pseudo
     CDS             complement(4240..5311)
                     /locus_tag="ACG8LA_002792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327954.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         1653 a         1082 c          838 g         1738 t
ORIGIN      
        1 ttttactaga acacaaaaaa aaccttaaaa ccaaacttaa gaagtttagt tttaaggtta
       61 acttaaatta tattatgcgt ggaaacgttc cacgccatct agataagttg cttccaatgt
      121 catatcaggg ttcaatacga taaagtctgc atcgcgtcct tgagcgattt ttccacatgt
      181 atcatcgatt ttacagctga ttgctggaat cagactagcc atcatgactg cttgttctgg
      241 tgttgctaat ccccagtcta caacattttt aattgcttct ttcaatttca atatacttcc
      301 agctaagttg ccagattcta gacgtgctgt tccttctttt actactactg gaaattcgcc
      361 taaattgtaa tttccatcag gcatcccacc ggccatcata cagtctgtaa ttaatgcgac
      421 atgatcatgt cctgcttttt ccattaggat tcccgcagca tttggatgta catgatggcc
      481 atcacaaatc aattcagaaa agacatgttc taaagataat aacgcaccca ccatacctgg
      541 ttcgcgatga ttcaatccac gcataccatt gaaagcatgg acaaatacac ttgcgcctgc
      601 ttcaacagct ttttgcgctt cttctagtgt agcattactg tgtcctagag aaacaactac
      661 tccttcttca gtcacttgtt tgacaaactc ttctacacct tgacgttccg gtgctaaagc
      721 aatttttttg attaaaccac ctgaagcttc ttgccattca tggaaagtat ccaaatcagg
      781 atccccgaaa taacttgggt tttgtgcccc tttgtgttct tctgtgaaga aaggaccttc
      841 aaaatagatt cctttgattt tagctcctgg tgcttcctga tacattttgc cgattgtctc
      901 agctacatct tttaaacgtt ctttgcttga cgtcaatgtt gttggtaaaa atgaagtcac
      961 tccacaagat aacagacctt cagacatcac tttgatgcct tctgcatcat tatccattac
     1021 atcatgattc atatagccgt gaatatgtgt atctaccaaa ccaggagcaa tccatttgcc
     1081 gctttggtca atgatgttga cttctccctc aggtagttct ttggtgtatt caccaaaaag
     1141 tccatcggta atttcaagat agcctgcatg tttgacacct gacgctaaaa agaatttgtc
     1201 agcatagata aaagttctca ttctattctc tccctttgtt tttctacctc taaagtactc
     1261 ttatttagag aagaagtcaa gaatggtcta caccatttac aaattttttg aaatttgttt
     1321 cacagcttgt gctaagcctt catagaatgc tgctctttct ggttcttctt tacgcttgta
     1381 tattaagctt ttaagcacaa ataaatcatt gaggtaatag tagctattct tctcttgagc
     1441 ccaatagatt ccttgattca cctgttctaa cgcttcgtcg atttcatttt gatggaataa
     1501 gaaatttcca taattataaa aaatttgcga aaattcactt tttgatcgtt catcagctga
     1561 ttgatgcagc agttggatgc ttcgactcaa atagtagcgt gcttcagccg tttttcctgc
     1621 cacaccatat atttttccga tacaactaat cagttgtatt tctgtgtcag aaacatggat
     1681 tctttctttt tggctagagt agcttaatgc ttctttcaaa taataaaggg actgagagat
     1741 attttgacgc aacgtgaatt cgcaaacacc gagataataa taatagcgtt gaaagtcagt
     1801 tgcttgatac agattttcag aaatatcaga agattttagt acttgttcta acttccgata
     1861 atcacgtttt tggaaacaac tatccaacag ttcaaataat ttatcgtttg tccgagtagt
     1921 ttttcgagag agattcatca catgatcaat cgttacccct agccgttgac aaatctgcat
     1981 catcaccaat acattcggca gttcctcatt attttcgatc cgacttaata cactttgtga
     2041 acaaatatca tgcgaaagca ttttttgcgt cattttttgt tcttttcgaa tctctttaat
     2101 gatcgttcca aaggactcga ttaacgtttc cataagtatc ctccccaaaa tatgcgtatt
     2161 cgcattctat tcgtatttta ctttaggaag tcgcaaactt caagaaaaga cttgcaacta
     2221 aataatatac tttagttatt taagaaaact ccactagaaa gagagcctca gtgtgtttgt
     2281 ctgtggccct cctactgaaa aatttggttt ttaaaatcat ttttggcgat aggttgctag
     2341 gaattctctc attttcttag ctgtttgttt caaatcatcc attttaggaa gataaacgat
     2401 tcgaaaatga tctggctggt tccaattaaa tccaccacca tgtacaagta gaatatgatg
     2461 ttcatgtaaa aagtccaaaa cgaatttttc atcatccaaa atattgaatc gctttgtatc
     2521 aatttttggg aatatataaa aagcagcttt tggttttacg gctgaaagac caggaatatc
     2581 attgattgca ttatagatat attctctttg ttcatagatc cttccgcctg gcaggagcag
     2641 ctcatcgaca ctttgataac cgcctagcgc ggtttggata atttgctgag acaatacatt
     2701 ggaacacaaa cgcatggagg acaacatatt cagcccttct atatagcctt tgacgtgtga
     2761 cttatctcca cttaggacca tccagcctac tcgaaatcct gctacacgat gagatttgga
     2821 tagaccgttc agcgtaacaa cgaacaaatc aggcgctaat gtagcaatcg gaatatgttc
     2881 tagaccatcc atcactaagc gatcatagat ttcgtcggaa taaataatca ggttattttg
     2941 tcgagctact tcaacgattt cttctaataa ttcttttgga taaagtgccc cagtaggatt
     3001 attaggatta atgataacaa tagcttttgt ccgactcgtt atttttgatt tgatatcatc
     3061 aatatcagga taccattctg cctcttcatc gcaaatataa tgaacaggtg tgcctccagc
     3121 taatgcaata gaagccgtcc acaacggata gtccggcatt ggaaccagta cttcatctcc
     3181 attgtccagc aacccctgca tacacatcgt gatcaattcg ctcactccgt tgccggtgta
     3241 gatatcattg atcgtcacat tcggaaaatg tttcagttgg caatattgct caattgcttt
     3301 tctagcagaa aagatcccct tggaatctga gtagccttct gagtcacggg cattcatgat
     3361 caaatcacga atgacttcgt ttggtgcttc aaatccaaaa ggtgcgggat ttcccgtgtt
     3421 caattttaaa atactaatgc cctcttcttg catccgctcc gcttcttcta gaacgggacc
     3481 gcgaacatcg taactgacac cttctaattt gttggatttt tcaaattctc tcatcactta
     3541 gccaatccct catttcaaaa agttagaact ttccaaattt tttgttattt actatttcaa
     3601 tatcatactc catcctagaa aattttgcca cttatttagg aaaaacgtaa gtattaaaaa
     3661 aacacaaaca agcgttgaga acttaattgt catgatagtc attccataga ttcgctgccc
     3721 aatccattgc aattccacaa atgattccta gcataaaacc aagcaaaaaa cgtccgaatg
     3781 caagtccaat caatacacct aagatcattc ccagtcctga aaattctccg tcatatttct
     3841 ccatcttaat aagtcctccc atttttgagc ttgacaacta tgtaaaacct cgctatcatt
     3901 agtgtgttat tattacgcag atgtgttgga attggcagac aagcatgatt gagggtcatg
     3961 tgagcgttag ctcgtgtggg ttcgagtccc atcatctgca ctacaactcg tgaagttaat
     4021 tttgcttcac gagttttttt gtttgaacgt ttctttatgc cattatatac atatcactgt
     4081 atcctttaca aaaagaacgt acaatcatgt aaacagcctg aggtgagtat atgaaggtcg
     4141 gaaacaagct actcgtagaa acttgcaagt gttaaaacaa ttaatcgaaa aacgagtaaa
     4201 atccctcacc taatactaaa gcgagggatt ttttgtatat tatctgttta tcaccgttat
     4261 tataaaggta caaataccaa gcacggttaa tccaaattgc ataaattcat ttttttgtac
     4321 actcatgctt ttcattagct ctttaactgc cattagtact aagatggcga taacaacata
     4381 aagtatatag tacgtccgca ttccggaagc ccatactgtg ggagaaaatc ccataattaa
     4441 ccttgaacaa aatcccatta tcatcaaaat aactaaaaaa atagaagttt tcttattgtc
     4501 aaaacttaaa taaattccaa caattaaaca tagtaataat gccaagacta ctaaagtagc
     4561 tatccaagta cctggataaa aaagtgacag tttcgttcct aactctgtaa agagattatt
     4621 caggttacta ctactccaaa tcattgccct tttatttcca ttgacgtaag taaagctttg
     4681 acccattgta ttaccaaaat aaataatcag gtttaagaaa aacggtaatg cagtcaatat
     4741 acgcacataa tagttttgac atttcctata tgttagaagg aaaattaaga aaaatagcaa
     4801 taaaaataag atattcatgt ctaaaaaaac ggctttccaa atgatgaaat acctaaatct
     4861 aacttattaa gaaagttgaa atttttatat tcaggaaacc atttattaat ttcatgtgca
     4921 gcacgtaatg cattccctgg agttgtcaaa gagaaaatta attctgctaa gcttattatt
     4981 gaaaatactg ataacttata attatatcgt ccattgacaa tcaaatataa actaactata
     5041 cttgttagaa caaaaaaaca ggcgttgact tgttcttgat tagttaaaaa tatcaataaa
     5101 ggaatactta cccaatatat ttttctattt atttcttctc ctcttaagag ttgaaaaaac
     5161 ggataaaaag ttagtaaact aaatgctact ggccactgat agttcaaggt ggttgctctc
     5221 caaccggttt cccccattac tgtcaatggt attaaacagt atatagagca aaccaataat
     5281 aaatttttaa catttatttt ctcaaaaaca t
//
LOCUS       DAZKKZ010000116         5207 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.121, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000116 DAZKKZ010000000
VERSION     DAZKKZ010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5207)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5207)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5207
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.121"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..1368
                     /locus_tag="ACG8LA_002793"
     CDS             <1..1368
                     /locus_tag="ACG8LA_002793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0205041.1"
                     /translation="SFYYGEKFFKKIDAAFLFSCLYTFATYRTVDIYYRSAIAEAIAL
                     TIIPAVLYYAYGLIFNREKKVIALSVSISLLVYTHVLTTLLCSALIACMIIVRLFLSK
                     QIKNDIKFVVVNLVKAVFLTCALTSYFWYPMLQQMNYQEIHSPFKTDLQLEALSISDS
                     IIQALNNDITTYTMGLLGLVALIFPLFILKEMEKKEKIIYVGVVSTWVCVTNLFPWFL
                     FQKTPISLLQFPWRILGIQIFFSSMIITLVFMKKTMNKKYSWLIIGATVVFLLVTSIA
                     AKENYAKVIQSKHGHIVINEETLPRYTTSDMGGLYDYAPTEAIKERPHLEKHEVKVGE
                     SWEKGKYKAADNNITYTVASNKKQKVTVPVYAYLGTQVKVNGKVVNDSYKKHGLVNVD
                     VNAGENKIEITTKYTPTALMALWISILTYCLVVYSSFKRFAPNKLKDSRYVTKKEINK
                     KNENK"
     gene            1355..2989
                     /locus_tag="ACG8LA_002794"
     CDS             1355..2989
                     /locus_tag="ACG8LA_002794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-pyruvoyl-tetrahydropterin synthase-related
                     protein"
                     /protein_id="HFQ0205042.1"
                     /translation="MKINKKVVILSGLIIVSSIYSFIFFKNTQSIYTTGDLSFHLSRI
                     KGLSTIFTSPINYETFNYTGYGVNYFYPFLTFFPAVMLYWMTKNLIVSYIIYVWLLNL
                     CTTLVAYHYGERFLKQKKAAFLFSCLYIFSAYRTVDIYYRSAIAEAIAITLVIPVLFY
                     AYQIISGKEEKYPSVKLALSMSLLVYSHVLSTLMSTALIIIFIFIRLVSKGFKNADFI
                     AIFKKLFSAAGMTLVLTSAFWYPMFEQMLYQKINKPSVTNLYAHASNVFDSLTEAMNN
                     DLTTYSMGLVGLLSLCIPLILFKKLTNIEKKIYYGTCLTWLATTSLVPWYLLQNTPAK
                     LLQFPWRILSLQIIFSSLILTMIFFKNRRYNKTRELFYLFMTVLLLITLTVSSKKNFN
                     QKIISQPGHIVVNKETVEAYTTKGMDYFLYDYSPIASLENKEHIIKHEAKIGSQWVNL
                     PYKTTGSSIIYRVTNEKSQVITLPVYAYLGTNVEINHQPVKEQVNANGLVQISGVKGV
                     ADIKVSTSYTVTTIISYLVTLTAYLCLFFKIVFHKR"
     gene            3164..3997
                     /gene="msrA"
                     /locus_tag="ACG8LA_002795"
     CDS             3164..3997
                     /gene="msrA"
                     /locus_tag="ACG8LA_002795"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008113 - peptide-methionine (S)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_function: GO:0033744 -
                     L-methionine:thioredoxin-disulfide S-oxidoreductase
                     activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HFQ0205043.1"
                     /translation="MDEEQIFIQTLYNLILNPNTRDWERKVLIQTKNDIRENISVKEQ
                     LSKLEATLRPLAIRMNLTPDVMDFYLLITEGFDKEQKYDFSKHAMQDADYQERAVFAG
                     GCFWCMVEPFESKKGILSVLSGYTGGHVEKPNYDQVSGGYTGHVEAVEIIYDTREISY
                     SELLTIYWQITDPTDTFGQFQDRGKQYRPVIFYQGERQKELAEQSKQKLDSSGTFHQP
                     IVTKIEPAGTFWPAENYHQQFYKKQPKRYKKIQQARNQFLIYQRVKNKWQKNIRKNHF
                     D"
     gene            4077..5066
                     /locus_tag="ACG8LA_002796"
     CDS             4077..5066
                     /locus_tag="ACG8LA_002796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HFQ0205044.1"
                     /translation="MYIADSARYEKMEYRKSGHSGLKLPILSLGLWQNFGDYDPIHNQ
                     REILRGAFDMGITHFDLANNYGGPAGAAEKNFGRIFREDFQAYRDELIISSKAGYHMW
                     EGPYGEWGSRKSIISSCDQSLQRMGLDYVDIFYHHRPDPDTPLEETAEALMQLVRQGK
                     ALYIGISNYNGEDTKKMTEILKRKEAPFIIHQMRYNMFSRALLEDDLSPVLEEEGLGA
                     ITFSPLAQGLLTNRYLHGIPEDSRAHRKEIPFLSEEQVGSTLEKIKALQTIAVSRGQS
                     LAQMALAWNLRQKSVTSVLVGASRLSQLQESVRMMDNLDFSPEEELRIDQILE"
BASE COUNT         1825 a          806 c          951 g         1625 t
ORIGIN      
        1 agtttttatt atggagaaaa gttttttaaa aagatagatg ctgctttttt atttagttgt
       61 ttatatactt ttgcaactta tcgaacagtt gatatctatt atcgatccgc aattgcagaa
      121 gcaatcgctc ttacgattat cccagctgtt ttatattatg cttatggatt gatattcaat
      181 agagaaaaaa aagtcatcgc tttatctgtc agtataagtc tacttgtgta tactcatgtc
      241 ttaactacac tattgtgtag tgcattgatt gcttgtatga ttatagttcg tttgttttta
      301 agcaagcaaa taaaaaacga tataaaattt gtggtcgtga atttagtaaa ggctgttttt
      361 ttgacttgtg cattaactag ctatttttgg tatcctatgt tgcagcagat gaattatcaa
      421 gaaatacaca gtcccttcaa aacagatttg cagctagaag cactttctat ttcagatagt
      481 atcattcaag cgttaaataa cgatattaca acatacacta tggggttatt aggattggtt
      541 gcgttgattt ttcctttatt catactgaaa gaaatggaga aaaaagaaaa aatcatctat
      601 gttggcgtag tttctacatg ggtatgcgta actaatttat ttccatggtt tttgtttcaa
      661 aaaacaccga taagcttgct ccagtttcct tggcgtatct taggtatcca aatctttttt
      721 tcttcaatga tcataacgct tgtttttatg aaaaagacta tgaataaaaa atattcatgg
      781 ttaatcattg gcgctactgt ggtgtttcta ctcgtcacgt ctatagcagc aaaagaaaat
      841 tacgcaaaag ttatccaatc aaaacacggt catattgtta tcaatgaaga aacactccca
      901 cgttatacaa catcagatat gggaggatta tacgattacg ccccaacaga agcgataaaa
      961 gaaaggcctc acttagaaaa acatgaagta aaagtaggag aatcgtggga aaaagggaag
     1021 tataaagctg cagataataa cattacttac acagtggcaa gcaacaaaaa gcaaaaagtg
     1081 acagtaccag tatatgctta tttaggtaca caggtaaaag taaacggtaa agtcgtaaat
     1141 gactcttata aaaaacatgg cttagtgaat gtggatgtaa atgctggaga aaataagata
     1201 gaaattacaa caaaatatac tccaactgct ctcatggctt tatggatcag tattctgact
     1261 tattgtttag tggtgtattc aagttttaaa cgatttgcac ctaataagtt gaaagattct
     1321 cgatatgtga ctaaaaagga gataaacaag aagaatgaaa ataaataaaa aagtagtaat
     1381 attgagtgga ttaattatag ttagtagtat atattctttc atctttttca aaaatacaca
     1441 gagtatttat accactggag atctttcttt tcacttatct cgaatcaagg ggttatcgac
     1501 tatttttacc agtccgatta attatgagac attcaattat actggatatg gtgtaaatta
     1561 tttttatccc tttctgactt tttttccagc tgtaatgtta tattggatga caaaaaattt
     1621 gattgtaagc tatattattt acgtttggtt attgaacttg tgtacaacac tcgtagctta
     1681 tcattatggc gagcggtttt taaaacaaaa aaaagcggca tttttattta gttgtctcta
     1741 tattttctct gcttatcgga cagtagacat ctactatcgt tccgcaattg ccgaagctat
     1801 cgcaataaca cttgttatcc ctgtattatt ttatgcttat caaatcatct ctggaaaaga
     1861 agaaaagtat ccgtctgtaa agctagcatt gagtatgagt ttgctagtgt acagccatgt
     1921 actatcaaca ttaatgagta cagcattaat tatcattttt atttttattc gtttggtttc
     1981 taaaggtttc aagaatgcag attttattgc tatatttaaa aaattattta gtgcggcagg
     2041 aatgacattg gttctgacga gtgctttttg gtatccgatg tttgaacaaa tgctctacca
     2101 aaaaatcaac aaacctagcg tgacaaattt atatgctcat gcatctaatg tgttcgatag
     2161 tctgactgaa gctatgaaca acgacttaac tacttactca atgggactag ttggtctgtt
     2221 atctttatgt attcccctga ttttatttaa aaaattaaca aacatagaaa aaaagattta
     2281 ttatggtacg tgtttgactt ggctagctac aactagtttg gtgccatggt atcttctgca
     2341 aaatacgcca gccaaattgt tacaatttcc ttggcggatc ttaagcttgc aaataatatt
     2401 ctcttctctg atattaacga tgatattttt caaaaataga agatacaata agacaagaga
     2461 actattttat ttatttatga ctgttttgtt attaatcact ttaactgttt ctagtaaaaa
     2521 aaatttcaat caaaaaataa tttctcagcc gggacatatt gttgtaaaca aagaaacagt
     2581 agaggcgtat accactaaag gaatggatta ttttttatat gattattctc ctatcgcttc
     2641 attggagaat aaggagcata taataaaaca cgaagcaaag attggcagtc aatgggtaaa
     2701 ccttccttat aaaacaactg gtagttctat catatataga gtaactaatg agaagagcca
     2761 agtaatcaca cttcctgtat atgcttattt aggaacgaat gtagaaataa atcatcaacc
     2821 tgtaaaggag caggtgaatg ctaatggatt ggtacaaata agcggagtca aaggagttgc
     2881 tgatattaaa gtaagcacaa gttatacagt aacgactatt atttcttatc ttgttacatt
     2941 aactgcatat ttatgtttat tttttaaaat agttttccat aaaaggtaaa ttaacttttc
     3001 atttataaaa taaattgatt aaaaaggaga atctgtcgat aaggattctc tcttttttat
     3061 acgaaaaatc tgtaggggga tgaagtaatc gcttatttcc tcactttatg ataaattaca
     3121 gctaaagtca ctagcttgtc ttcttcggaa aggaggagaa tctatggatg aggaacaaat
     3181 attcattcaa acactttata atctgatttt gaatccgaat acacgagatt gggaacgaaa
     3241 agtattgatt cagacaaaga atgacataag agaaaatata tccgttaaag aacagttatc
     3301 aaaactagaa gcaacactac gtccattagc tatccgaatg aatctgacgc ctgatgtaat
     3361 ggacttttat ttattgatta cggaaggatt tgataaggag caaaaatatg acttttccaa
     3421 gcatgccatg caagatgctg actatcaaga acgtgcagta tttgcagggg gatgtttctg
     3481 gtgtatggtc gagccgtttg aatcgaaaaa agggatccta tctgttttgt caggatacac
     3541 gggcggacat gttgaaaaac caaattatga tcaagtaagt ggtggttaca caggtcatgt
     3601 ggaagctgtg gagatcattt atgacacaag agaaataagt tatagcgagt tgctgacaat
     3661 ctattggcaa attactgatc ccacagatac atttggacaa tttcaagata gagggaagca
     3721 atatcgtcca gtgatttttt atcaaggcga acgacaaaaa gaattagcgg aacaatcaaa
     3781 acagaaacta gacagttcag gaactttcca ccaaccaatc gtcacaaaaa tcgaaccagc
     3841 cggtacgttt tggccagcag aaaactatca tcagcaattt tacaaaaaac aaccgaaacg
     3901 ttataaaaaa atccagcaag cacgtaatca atttctgatc tatcaacgag taaaaaacaa
     3961 atggcaaaaa aatatacgaa aaaatcattt tgattaactc cttttcttta aaatgtagta
     4021 aactaaaaat agaaaaaaga aagcgtttta aaaagatttg atgaggagga gaaaaattgt
     4081 atattgcaga tagtgcacgt tatgaaaaaa tggaatatcg taaatccggt cattcaggtt
     4141 tgaaattacc gattttatct ctcggattat ggcaaaattt tggtgattat gatcctatcc
     4201 ataatcaaag agagatttta agaggcgcat tcgacatggg aattacccat ttcgaccttg
     4261 cgaataatta tggaggccct gctggagctg cagagaaaaa ctttgggcgt atttttagag
     4321 aagattttca agcctaccgt gatgaactga ttatttctag caaagcaggt tatcatatgt
     4381 gggaagggcc atatggggaa tggggctctc gtaaatccat catttcaagt tgtgaccaaa
     4441 gtctccaaag aatggggcta gattatgttg acatcttcta tcatcatcgc ccagaccctg
     4501 atacaccttt ggaagaaaca gcagaagctt tgatgcaact tgtaagacaa ggaaaagcat
     4561 tatatattgg tatatccaac tataatggag aagatacaaa aaaaatgact gaaattttaa
     4621 aaagaaagga agcaccgttc attattcatc agatgcgcta caatatgttt tctcgtgcac
     4681 tactagaaga cgatctatct ccagtattag aagaagaagg gctaggggca atcacgttca
     4741 gtccgcttgc tcaagggttg ctgacaaatc gttatctaca tggtattcct gaagattcta
     4801 gagcacatcg taaggaaata ccattccttt cagaagaaca agttggatca actctggaaa
     4861 aaatcaaagc actgcaaaca atcgccgtat cacgaggaca atcattagcg caaatggccc
     4921 ttgcatggaa tttgcgacaa aaatctgtta caagtgtact ggtcggagca agtcggttaa
     4981 gtcagttaca agaaagtgtt cgaatgatgg ataatttaga tttctcacca gaagaagaat
     5041 tgagaatcga ccaaattcta gaatagaaac gatgtaatca aactttttat ccatatatta
     5101 aaaaaaacaa aagatgacat caagaatcga atgaagatcg tctgttattg aacatcatat
     5161 tttttgtcgt tcaaaataaa aatgatcgaa ggctaggagt gaatttt
//
LOCUS       DAZKKZ010000117         5184 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.122, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000117 DAZKKZ010000000
VERSION     DAZKKZ010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5184)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5184)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5184
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.122"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..447)
                     /locus_tag="ACG8LA_002797"
     CDS             complement(<1..447)
                     /locus_tag="ACG8LA_002797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0205045.1"
                     /translation="MNYEFFLSKEDHRSYSLLKYLEASSNLSESISNVQEELSLSTFL
                     LKKTIDKLKHDLQKFDLEKNLRVTVSELDICLEINGKCSSKALLSRYITDSLSMKMVL
                     AFFQEKYISVENFAKQHHVSYSVAYKVLQRLKRNLKKYQIFFEKRKL"
     gene            complement(754..1851)
                     /locus_tag="ACG8LA_002798"
     CDS             complement(754..1851)
                     /locus_tag="ACG8LA_002798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HFQ0205046.1"
                     /translation="MIKGAIFLRPKQQLFITLLVILGALFNNISVSASAFNFSVTPIT
                     SENQIDKRKTYFDLQLDPDQEVEVKAELRNDTEKEVKIDISVNSATTNSNVMVEYGKN
                     EIEKDMSLIFDLVDYVSYPQIVTLKPKSVQTVAFHVRMPNERFDGVLAGGITFQEIQT
                     EKDQTETKDQSLSIENEYTYIIALLMQQTLNEVAPNLTLHEVKPDQINARNVILANVQ
                     NDQKTYINQVVIETKITKKGHSEVLYQEEKEGLQIAPNTNFSFPTALNGQPLTPGEYH
                     LTMTVLGNENENGKFSRKKGNTTINYTNQWVFEKDFTIDGKVAKELNTTDVTIKKDNN
                     WIYILVASLFLLFILLCILLFVLRKKEEKEK"
     gene            complement(1959..3986)
                     /locus_tag="ACG8LA_002799"
     CDS             complement(1959..3986)
                     /locus_tag="ACG8LA_002799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HFQ0205047.1"
                     /translation="MKKRRIVLILSSLLVTNIFPIIGYSLELNQLEHGNRRDEESKLT
                     STFDSLIESNQTQESSEDLSISSSGETTDNVEAEGSDKQGLEDAPISAVELPDDPNII
                     SIDKIFQTPIGTSTSILENGKLLQLNPAERSQRGAIWSNKKISLLSDFTFKSYLYLGN
                     QRDRAGDGMTFTLTGDPRMASNPSQVIGSPGMGIGSYSTRSGQPYIANALSIEFDTYK
                     NSGSSDRMDREITADNRGHGHVAFVTPKPNNNNYSGEHTGVTVAPTFLSNGTWRLLII
                     KWDAEQRSLTYDLEGVGRSSRIIPDLIRQFGSTEVNWGFTSSTGTFFQENAVAVTRLP
                     SNVTSTADVKVNDSDYGAIAEAGGNDKITIRNTLKVEGDFLEYKKMQTSIDLPQELTI
                     PEHILINGNQIDAKDILITGNRVTLNLTDYFIAGDTLIIELETTLQEVIPEKVLTMHF
                     EYLENGNLIEQSNEINLKIAKLKEIDIHVYYKDKDSQIDIAEMKTITGKIGEKYKETP
                     IDIEGYVFDSDSANTEGIFSENTEDIYFYYRKGKLYLSTAPQYVNFGKHKISSRPLSE
                     FGQFSGGLKIIDERAFGSWKLQLKQEKVLTNGDFELPEALSFVTSENTTVIGTSAVTI
                     FESDQKGESDLSSLLDSTAHRGIRINIPVENQRIGTFEGKLSWILADVPGN"
     gene            complement(4131..4859)
                     /locus_tag="ACG8LA_002800"
     CDS             complement(4131..4859)
                     /locus_tag="ACG8LA_002800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HFQ0205048.1"
                     /translation="MKKEIVLTAAMMLFSMVASTTFVSATEVYPKEYNTEGTITFEAG
                     DEGVTPPVDPENPDPNKPVDPSDPPSPGTGGALSIDYGSKFKFGTQKISTADKTYYAA
                     ADVMNDGSRKPTYVQVTDRRSTLSGWKLSVSQPEQFKTASGDELVGAQLKFTKGQAVS
                     LVDPTYTPQTVNSELTLTPGGNNTLAINAKSGTGVGTWVYRFGANENENQDAVQLSVP
                     GKSVKLAQQYSTKLVWTLEDTPNN"
BASE COUNT         1475 a         1045 c          812 g         1852 t
ORIGIN      
        1 caactttctc ttttcaaaaa aaatttgata tttttttaga tttcttttta gtctttgtaa
       61 tactttataa gccacagaat aactcacgtg atgctgttta gcaaaatttt ctactgagat
      121 atatttttcc tgaaagaaag ccaataccat tttcatagat aaagaatccg ttatataacg
      181 agataacaga gctttgctag aacattttcc attaatttcc agacatatat ccaattcact
      241 gacggttact cgcaaatttt tctctagatc gaacttttgt aaatcatgtt tcagcttatc
      301 gatcgttttt ttcaagagaa atgtcgatag cgacaactct tcttgaacat tcgatattga
      361 ctctgataaa tttgagcttg cttctaaata tttaagtaat gaataacttc tgtgatcttc
      421 tttgcttaaa aaaaactcat aattcattag tcatcagctc tttctacgta tattactttc
      481 catgcattca ccaactagct ggggataaaa ctgatttcct ggatccgagt cactgttgtc
      541 agcgattctt gtttgtataa tatacatcgt cctgtctttt ttttaacatt ttggagagcg
      601 ttttatttgg cctttctcgc gatcaaacct gttattagaa ttatatcatt tactagtatg
      661 catttttatt aataaaatgg tatattttat attgttataa aaagagccca accatcctac
      721 aataataaaa atttactatt tgttatctta accttacttt tctttctctt ctttttttct
      781 caaaacaaac aaaagtatgc ataataaaat aaacaataag aaaagtgaag ctactaagat
      841 ataaatccaa ttattgtctt ttttaatcgt aacatccgtc gtgttcaatt ccttggctac
      901 ttttccgtct attgtaaaat ctttttcaaa tacccattga ttggtatagt tgatcgtagt
      961 atttcctttt tttctcgaaa attttccatt ttcattttca tttcctaaaa cagtcattgt
     1021 aaggtgatat tcacctgggg ttagcggttg accatttaaa gcagttggaa aagaaaaatt
     1081 tgtattcggc gcaatctgca atccttcttt ttcctcttga tataaaactt cagaatgtcc
     1141 tttttttgta atttttgttt caataactac ttgattgata taggtttttt gatcattttg
     1201 aacgtttgct aagatgacat ttcttgcatt gatttgatct ggtttaactt catgaagagt
     1261 aaggttcgga gcaacttcgt tcagtgtctg ttgcatcaac aaagcaataa tataggtgta
     1321 ttcattctca atcgataagc tttgatcctt agtttctgtt tggtcctttt ccgtctggat
     1381 ttcttggaat gtgatcccac cagccaatac accatcaaat cgctcattcg gcatcctgac
     1441 atgaaaagca acggtttgga cacttttagg ttttagcgtc actatctgtg gatagctcac
     1501 ataatctacc agatcaaaga tcaggctcat gtctttttca atctcgtttt ttccgtattc
     1561 aaccatcaca tttgaattgg tggttgcgct attcacagaa atatcgattt tcacttcttt
     1621 ttctgtatca tttctcaatt ccgcttttac ttctacttcc tgatccggat caagttgaag
     1681 atcgaagtaa gtttttctct tgtcgatttg attctctgaa gttatcggcg tcactgaaaa
     1741 attaaatgca ctagctgaca ctgatatatt gttaaaaagt gcccctaaaa taactaggag
     1801 tgttataaat aattgttgtt ttggtctcaa gaaaatcgct cctttaatca tatgtaagag
     1861 aagactataa caaaatcttg tctctgtggg acacaagagc ctatggtacc tgtgcccttc
     1921 ttgaaactca ataattttgt tatattcttc tcttcctgtt aatttcctgg gacatctgca
     1981 agtatccaag atagtttccc ctcaaaggtt ccgattcttt ggttttctac aggaatattt
     2041 attctgattc cacgatgagc tgtagaatct aaaagagagg acaaatcgct ttcacccttt
     2101 tgatcacttt cgaaaatcgt aacagcggat gtccctataa ccgttgtatt ttcagaggta
     2161 acaaaggaaa gagcttctgg aagctcaaaa tctccatttg taagaacttt ctcttgtttc
     2221 aattgtaatt tccaacttcc aaaagcccgt tcatctataa ttttcaaccc acctgaaaac
     2281 tgtccgaatt cacttaatgg tctactggat attttatgtt ttccaaaatt gacatattga
     2341 ggagcagttg agagataaag tttgcctttt ctgtaataaa aatagatatc ctctgtattt
     2401 tcggagaaga tgccttctgt attcgctgaa tccgagtcaa aaacataccc ttcaatatca
     2461 ataggagttt ctttatactt ctctcctatt ttcccagtga ttgttttcat ttcagcaata
     2521 tcaatctgac tgtctttatc tttataataa acatggatat ctatctcctt cagctttgcg
     2581 atctttaggt ttatttcatt cgattgctca atcaaattcc cgttttcaag gtattcaaaa
     2641 tgcatagtga gtactttttc aggaattact tcctgcaaag ttgtctccaa ttcgattatt
     2701 aacgtatctc cagcaataaa ataatctgtc agatttagcg tgactcgatt tccggttatc
     2761 aagatatctt tggcatcaat ttgatttcca ttgatcaaga tatgctcggg aatagttaat
     2821 tcttgtggga ggtcgatact agtctgcatt ttcttatatt caagaaaatc cccctcgacc
     2881 ttcaatgtat ttctgatagt tatcttatcg tttcctccag cttcagcgat ggccccataa
     2941 tcactatcgt tgacttttac atcagctgtt gatgtgacat tcgatggaag tcgcgtgaca
     3001 gcgacagcat tttcttgaaa aaaagtacct gttgaagaag taaaccccca atttacttct
     3061 gtagaaccaa actgcctaat gagatcaggt ataatccgag aagagcgacc gacaccttcc
     3121 aaatcataag taagacttct ttgctccgcg tcccatttaa ttattaacaa gcgccatgtg
     3181 ccattagaaa gaaatgtagg agctaccgtc acgccagtat gctctccaga ataattatta
     3241 ttatttggtt taggcgtgac aaaagcgaca tgtccatgcc ctctattatc agcagttatc
     3301 tctcgatcca ttcgatcaga agaaccacta tttttatacg tatcaaactc aatcgagagc
     3361 gcattcgcaa tgtaaggttg gccagaacga gtagaatatg agccaattcc catacctggc
     3421 gatccaataa cttgactggg attactagcc attctaggat cgccagtcaa tgtaaaggtc
     3481 atgccatctc ccgctctatc tcgttgattt cctaagtata aataagattt aaatgtaaaa
     3541 tccgagagta aactaatctt cttatttgac caaatagctc ctctttgaga cctttctgct
     3601 gggttcaact gcagtaactt cccattttcc aatatggacg tgctagtacc gataggtgtt
     3661 tgaaaaattt tatcgataga aataatattg ggatcgtcag gcagctcaac cgcagaaatt
     3721 ggtgcatctt ctagtccttg tttgtccgaa ccctcagctt ctacgttgtc agtggtctct
     3781 ccactactcg aaatacttaa atcctcactg ctttcttgtg tctggttgga ttctattaaa
     3841 ctgtcgaatg tcgaagtgag tttgctttct tcgtctcttc tatttccatg ctccaactga
     3901 ttcaattcca aagagtaccc tatgatcgga aagatattag tcactaagag actgcttaaa
     3961 atgagcacga tcctcctctt tttcaatata tcttttcctc ctgatcgtta aattcctaga
     4021 tgaactattc gtatccaaac aaatttagcc tagcctttga caatttttgc tcgattacct
     4081 cgcaagacaa tatgactacg tatttatttt taacagttct tttcagtaaa ctagttgtta
     4141 ggtgtatctt ctaatgtcca aactaattta gtggaatatt gttgcgctaa cttgacagat
     4201 ttaccgggta ccgaaagctg taccgcatct tgattttcat tttcatttgc accaaatcga
     4261 tagacccaag tccccacacc tgttcctgat ttagcattaa ttgctaacgt attgtttcct
     4321 cccggtgtca acgttaattc agaattcacc gtttgcggcg tatatgttgg atcaaccaaa
     4381 gaaacagcct gccctttcgt aaatttcagc tgtgctccaa ctagttcatc cccactggca
     4441 gttttaaact gttctggttg agagacactt aatttccacc cagataaggt acttctccta
     4501 tctgtcactt ggacatatgt cggttttcta gacccatcgt tcatcacatc agcagctgca
     4561 taatacgttt tatccgcagt agaaattttt tgagtcccaa atttgaattt tgatccataa
     4621 tcaatcgata atgcccctcc tgttccaggg cttggaggat ctgatggatc gacaggttta
     4681 ttgggatcag gattctctgg atcaacagga ggagttacac cctcatctcc tgcttcaaat
     4741 gtaatcgttc cttctgtgtt atattccttt gggtatactt cagttgcaga aacaaaagtc
     4801 gtacttgcta ccatgctgaa taacatcatt gctgctgtta atacgatttc ttttttcatc
     4861 attgacattc ctctttcttt atttactaaa catatcagtc gattggatta atccatagca
     4921 aaattctgtt ttacgatact tatgaaataa aagaacatag acctatattt ggtcctatgt
     4981 atcgattagt tataaatgat tatcagcccg atttgatttc tagtttttat tgcaacttga
     5041 tgcaaacaca atctagaaat acagctgtca tagcctttaa aataattcgt aagtccccct
     5101 cctatctatc aaaatgtgac ttgactgcct agacttcaat caatattaat tataattaaa
     5161 taaaaaatgt atattatatt tttt
//
LOCUS       DAZKKZ010000118         4931 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.123, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000118 DAZKKZ010000000
VERSION     DAZKKZ010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4931)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4931)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4931
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.123"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            85..972
                     /locus_tag="ACG8LA_002801"
     CDS             85..972
                     /locus_tag="ACG8LA_002801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HFQ0205049.1"
                     /translation="MQELKTRSARHHRPKRKMVINKKAIAPLIGTSLLVGPMMVTAVP
                     QHVHADEQGSQTVADPQAFIDQIGWSASEVAASNDLYASVMIAQALLESAYGTSGLAS
                     APNYNLFGVKGSYNGQVVYMATKEYVNGQWVTMNEPFRKYSSYWESFQDHANVLRSTS
                     FSTGDYHYAGVWKSNTTSFYDATAYLTGRYATDPNYGAKLNSLINTYNLTRFDTPSTG
                     SATTTTSTTTTTTTTTSTSSSSTTDVNTNNGQTYTVVSGDTLWDIAQKFGMSVDDLMA
                     KNGMSMSSYSLLVGQELNV"
     gene            1112..2038
                     /gene="cysK"
                     /locus_tag="ACG8LA_002802"
     CDS             1112..2038
                     /gene="cysK"
                     /locus_tag="ACG8LA_002802"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004124 - cysteine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HFQ0205050.1"
                     /translation="MTAIYNSVTELIGKTPIVKLNKIVPEDSADVFVKLEFFNPGGSV
                     KDRIALSMIEKAEHDGLLKPGDTIIEPTSGNTGIGLSMVGVAKGYKVIIVMPETMSIE
                     RRLLMKGYGAELILTPGADGISGSIREAERLAKENGYFLPLQFENEANPLVHEKTTGP
                     EIHQAFGVNGLDAFVAGIGTGGTITGAGRELKRVYPKIELIGVEPAESAILEGKEAGP
                     HKIQGIGTGFVPKTLDTSVYDKVLSISGDEAMETAREVGRKEGILVGISSGAAIAAAL
                     KVAKELGKGKKVLAVVPDNGERYLSTALYQEI"
     gene            2274..2720
                     /locus_tag="ACG8LA_002803"
     CDS             2274..2720
                     /locus_tag="ACG8LA_002803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fur family transcriptional regulator"
                     /protein_id="HFQ0205051.1"
                     /translation="MENKLVEEVIEKLKKENIRITPQRYAVLEYLIEHHSHPTADEIY
                     KALEHRFPNMSVATVYNNLRLFTSIGFVQEMKYGDASSRFDFSSKRHYHVICENCGKI
                     VDFHYPGLEDIEMAASRLTDFEINEHRLELYGLCPDCKESAKKAQM"
     gene            2993..4345
                     /locus_tag="ACG8LA_002804"
     CDS             2993..4345
                     /locus_tag="ACG8LA_002804"
                     /EC_number="7.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH oxidase"
                     /protein_id="HFQ0205052.1"
                     /translation="MKVVVIGCTHAGTAAVKSILKNHPEAEVTVYERNDNISFLSCGI
                     ALYVGGVVKDPAGLFYSNPEELSSLGATVKMEHDVTDVDTENKTVTAKDLKTGETETV
                     SYDKLVMTTGSWPIIPPISGIDAKNVLLCKNYNQANEIIAQAKEAKRVVIVGGGYIGI
                     ELVEAFVESGKQVTLIDGLDRILNKYLDKPFTDILEKELTDRGVTLALGENVTEFITD
                     EEGKVKQVATPTDTFDTDMVILCVGFRPNTKLIEGKVDTLPNGAIKVNEYMQTSNPDI
                     FAAGDSAVVNYNPSGTQNYIPLATNAVRQGLLVGNNLTDHKMAYRGTQGTSGLYLFGW
                     TIGSTGVTKESATLNDLEVQATVFEDNYRPEFMPTTEKVMMELVYEKGTNRIVGAQFM
                     SKYDITQSANTMSLAVQNKMTVEDLALSDFFFQPHFDRPWNYLNLLAQAALGEIETAQ
                     "
     gene            4516..4803
                     /locus_tag="ACG8LA_002805"
     CDS             4516..4803
                     /locus_tag="ACG8LA_002805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5960 family protein"
                     /protein_id="HFQ0205053.1"
                     /translation="MNKEYFVQQDAFLEDYKSASKKLTINIDELADQVLSQLNETQEE
                     YYTMPANDAKDNVSHRFPFSRRIYSDENDGTLNTEYTYEGQPYVLETDDDL"
BASE COUNT         1695 a          813 c         1030 g         1393 t
ORIGIN      
        1 aattaaaagt ataatttaat taattaagtt tgttttaaga agagaacttt ttattaagtt
       61 tttttatttt gaggaggaat ttgaatgcaa gagctgaaga cccgcagtgc ccggcaccat
      121 agacctaaaa gaaaaatggt gatcaataaa aaagcgattg ctcctttaat tggaacgagt
      181 cttttagttg ggccgatgat ggttacagcg gtaccgcaac atgttcatgc agatgaacaa
      241 ggatctcaaa cagtcgctga tcctcaagcg tttatcgatc aaatcggctg gtctgcgtca
      301 gaagttgctg caagtaatga cttgtatgct tcagtcatga tcgctcaagc gttgttggaa
      361 agtgcatatg gcacttccgg attagctagt gcgccaaatt ataatctatt cggtgtgaaa
      421 ggaagctata acggacaggt cgtttatatg gcaaccaaag aatatgtaaa cggacaatgg
      481 gtaacgatga atgagccatt ccgaaaatat tcttcttatt gggaatcctt ccaagaccat
      541 gcgaatgttc ttcgttcaac cagtttttcc acgggcgatt atcattatgc tggcgtgtgg
      601 aaaagcaata caacaagttt ttatgatgca acagcgtact tgacaggtcg ttatgctacc
      661 gatccaaatt atggggccaa attgaactca ttgattaata cttataattt aacccgtttt
      721 gatacgccat caacaggttc ggctacaaca accacaagta caacaacaac gactactacg
      781 acgacttcaa cgtcatcatc ttcaacaaca gatgtaaata caaataatgg tcagacatat
      841 acagtcgtgt caggtgatac gctatgggat attgcacaaa aatttggcat gtctgttgat
      901 gatctaatgg cgaaaaatgg catgtctatg tccagttatt ctttattagt tggtcaagaa
      961 ctaaacgttt gatttagata aaaaggcaaa gaaattacca tatatggtat atctttgtct
     1021 tttttttgct agtcaaagac gaatcactcg ccataaatga acagattgta ttatgataag
     1081 taagaagagc aaagacaagg aggaattgaa gatgacagct atctataact cagtcaccga
     1141 attgattggc aaaacgccaa tcgtcaaatt aaataaaatc gtaccagaag attcagcaga
     1201 tgtttttgta aagcttgagt tttttaatcc aggaggaagt gtaaaagatc gtattgcttt
     1261 aagtatgata gaaaaagcag aacacgatgg tctactgaaa ccaggtgata ctatcattga
     1321 acctacttct ggaaatacag gaatcggatt gtcgatggta ggagttgcaa aaggatataa
     1381 agtaatcatc gtgatgcctg agacgatgag tatcgaaaga cgtttattga tgaaagggta
     1441 cggcgcagag ttgattttga ctcctggtgc ggatggtatt tctggatcaa tcagagaagc
     1501 agaacgtttg gcaaaagaaa acggctactt tttaccatta caatttgaaa atgaagcaaa
     1561 tcctcttgtg catgagaaga cgactggtcc tgagatacat caagcatttg gagtaaatgg
     1621 cttggacgcg tttgttgcag gtatcggtac aggaggaacg atcactggcg ctggccgaga
     1681 attaaaacgt gtgtatccga aaatcgaatt aatcggggta gaaccagcag aatctgctat
     1741 tttagaaggg aaagaagcgg gacctcacaa aatccaagga atcggtacag gttttgttcc
     1801 taaaacactg gatacttctg tgtatgataa agtcctttct attagtggag acgaagcgat
     1861 ggaaacagct agagaagttg ggcgaaaaga agggatttta gtaggcatct catctggcgc
     1921 tgcaattgct gccgcgctaa aagtcgcaaa agaattagga aaaggcaaga aggtattagc
     1981 tgtggttccc gacaatggtg aacgttattt atctacagcc ctttaccaag agatataagg
     2041 cacttggttt ttctccagat aggtttatgt aaaaaacttt taaagatgaa aagaacacac
     2101 aaaaatttat gatgagaaaa attatttgaa tagagacgta gaatagtgaa cgcgactgtt
     2161 ttacgtcttt tttcattaaa atacaataaa attgaatttt cttttcatgt taagtggatt
     2221 ttaaaatgta aaaatagtat gataagacga gaataacaac gtggggtgtt tacatggaaa
     2281 ataagttagt cgaagaggtt atcgaaaagt taaaaaaaga gaacattcga atcacacctc
     2341 aacggtacgc ggttttagaa tatttgattg aacatcattc ccatccaacg gctgatgaga
     2401 tttataaagc acttgaacat cggtttccaa atatgagtgt tgcgactgtt tacaataacc
     2461 ttcgcttatt tacttcgatt ggatttgttc aagaaatgaa gtacggcgat gcttctagcc
     2521 gatttgattt cagttcaaag cgtcattatc atgtaatttg tgaaaactgc ggtaagattg
     2581 ttgattttca ttacccaggg cttgaagata tagaaatggc tgcaagcaga ctgactgatt
     2641 ttgagattaa tgaacatcgg ttggaattgt atggactctg tccggattgt aaagagtcag
     2701 caaaaaaggc gcaaatgtaa aaacagtttc tacaagtgtt atacctaaaa aaagctagct
     2761 gtgtaaaaaa aacgctagct tttttatttt tttgtctttt attcacaatc ttagatataa
     2821 aagtgaatat tattaaaata agaatcttgt agatattggg ttcttatgct tgaaaaggaa
     2881 tgaaactaca aacaaacctt tgtgaattca caagcattaa actgttgtat ccgttttatt
     2941 tctgttatag tagttttgtc gaaggacaaa atgttaatcg gagggaccat aaatgaaagt
     3001 agtagtaatt ggctgtactc atgcaggtac tgcagctgta aaaagtattt taaaaaatca
     3061 tccagaagca gaagtgacag tatatgaaag aaatgacaat atttctttct tatcttgcgg
     3121 tatcgcactt tatgtcggcg gagtagtaaa ggacccagca ggcttgttct actcaaatcc
     3181 tgaagaatta tcttcattag gagcaacagt taaaatggaa cacgatgtaa cagacgtcga
     3241 tacagaaaat aaaacagtaa cggcaaaaga tctgaaaaca ggagaaacag aaacggtttc
     3301 ttatgataaa ttagtgatga caactggttc atggcctatt atcccaccga ttagtggaat
     3361 cgatgcgaaa aatgtactcc tatgcaaaaa ctacaatcaa gcaaatgaaa ttattgcaca
     3421 agcgaaagaa gcaaaacgtg tagtaattgt tggtggtgga tatatcggta ttgaattagt
     3481 agaagctttt gtcgaatctg gaaaacaagt gacattgatt gatggattag atcgcatctt
     3541 gaataaatat ctagataaac cattcacaga tatcttagaa aaagaattga cagaccgcgg
     3601 tgttactctt gcgctaggcg aaaatgttac tgaatttatc acagatgaag aaggaaaagt
     3661 gaaacaagta gctacaccaa cagatacatt tgatacagat atggtcattt tatgtgtggg
     3721 cttccgtcca aatacaaaac tgatcgaagg aaaagtagat acactgccaa acggggcaat
     3781 caaagtgaat gaatacatgc agacaagtaa tccagacatt tttgcagctg gagactctgc
     3841 agtagtcaac tacaatccaa gtggcacgca aaactatatt cctttggcaa caaatgccgt
     3901 tcgtcaaggt ttgcttgtgg gaaataactt gacagatcat aaaatggcgt atcgtggtac
     3961 tcaaggaact tcaggacttt acctatttgg ctggacgatc ggttcgacag gtgtgaccaa
     4021 agaaagcgca actttgaacg atctagaagt ccaagcgact gtatttgaag ataattatcg
     4081 tccagagttc atgccaacta ctgaaaaagt aatgatggag ctagtctatg aaaaaggaac
     4141 gaatcgtatc gtaggtgctc agttcatgtc caaatacgac attacacaat cagcaaatac
     4201 catgtcttta gctgttcaaa ataaaatgac tgtagaagat ctcgcacttt cagatttctt
     4261 cttccaacca cattttgacc gcccatggaa ttacttgaac ctacttgcac aagcagcgct
     4321 aggcgaaatc gaaactgcac aataaagaaa aagggttgtg acacaatttt gtcacgaccc
     4381 tctgtctttt tttgtgaaaa gtacaattag ttgtctttct tcgaattttt tgtcacaata
     4441 agcagcaaag ataaagctgt tacataaaag aacaagcagc tttatttgat tttgaaaaga
     4501 aaggtgagaa agaagatgaa taaagaatat tttgtccaac aagatgcatt tttagaagat
     4561 tataaaagtg cttcgaagaa attaacgatc aatattgatg agttggcaga tcaagtactc
     4621 tctcagttga atgaaacgca agaggaatat tacacgatgc cagcaaatga cgccaaagat
     4681 aatgtttctc atcgttttcc tttcagtaga cgcatctact cagatgaaaa tgacggcaca
     4741 ttgaatacag agtacacata tgaaggtcag ccatatgtgc tagaaactga tgatgatctt
     4801 taaagacagt ttttgaaaag gccgctcatc cttaagtgat gacaaaaaat catcacaatt
     4861 accgatgact gtctctttac tatcttttaa tcagaaaaag gggttatgac aagctttgtc
     4921 aacccctttt t
//
LOCUS       DAZKKZ010000119         4884 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.124, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000119 DAZKKZ010000000
VERSION     DAZKKZ010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4884)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4884)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4884
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.124"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            509..2353
                     /locus_tag="ACG8LA_002806"
     CDS             509..2353
                     /locus_tag="ACG8LA_002806"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HFQ0205054.1"
                     /translation="MNYKQTAEEVLQYIGGEENISHLEHCSTRLRFTLKDNSKVNMSQ
                     LEKVDGVMGVRQNVQCQVIIGNDVVEVYDEVKALLGDNVSNTEEAPKQKQKLGSVLLD
                     FIISIFQPLIPAIAGGGVLKSLLLLASILGLISDQSQTYQILNLVGGAPLYFLPILVA
                     MTTANKLKVNQLVAVSAVGALILPEMTAMLAEGATFLSFGLDNIAYASQVFPAILTVL
                     FYAQLEKWFTKVSPKPIRIFFVPMMSLLITVPIALLLLGPLGYNVGTAFSSIIVSLYN
                     QFGWVATGVLAAVLPLMVVTGMHKAMIPYAVSSMSELGAELLYLPASLAHNISEAGAC
                     FAVSIKTKDKKLKSTAVSAGISALFGITEPALYGVTILHKRVLYAVMFSSLIGGAFAG
                     IVALQAFALVGPGIASITMFADKADPMNLVWAFAVSGISFVVAFAAALVLYKDKEVVN
                     EVETKMETAVVSDAVLSSPVNGKVISLSEVKDTVFSSGMVGDGVAIIPEEGILVAPED
                     GEITMVFETKHAIGLKTANGAELLFHIGIDTVQLEGKGFEAFVRSGEKVAKGQKLIAF
                     DIDLIKEAGFDPTVICVVTNKDNYTIRSFNLEKLVTNDSDLLAISPIA"
     gene            2409..3875
                     /locus_tag="ACG8LA_002807"
     CDS             2409..3875
                     /locus_tag="ACG8LA_002807"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016620473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFQ0205055.1"
                     /translation="MTNTTSFPKGFLWGGAIAANQVEGAWNVDGKGLSVADMATYKPN
                     LDNKDFAAHMHVTLQSIKEASEDKSDKWYPKRRGVDFYHHYKEDLALFAEMGFKTLRL
                     SIAWTRLFPTGEELEPNEKGVAFYENVFKEMQRLGIEPIVTLSHYEMPLALAVKYNGW
                     VERRVIDDFVRFANVCFDRFGKYVKYWLTFNEIDSIHRHPFTTAGIIQEKSAEGQEAQ
                     DIYQALHHQFVASALVTKDAHEKIPGSQVGCMLTKLMTYPLTCAPEDVELTLKKNLEN
                     NFYADVQVKGEYPALIEKDLENRGIQIKMEDEDREILKKHTVDFVSFSYYMSMAESAD
                     PNAERTPGNTVLGVKNPHLPSTDWGWQIDPKGLKISLIELYDRYQVPLMIVENGMGAV
                     DQVVDGKIHDPYRIDYFKAHFQQMKEAIDEGVDLIAYTSWGPIDLVSAGTSQMSKRYG
                     FIYVDADDEGNGTYNRLKKDSFNWYKEVIETNGASLFE"
     gene            3912..4754
                     /locus_tag="ACG8LA_002808"
     CDS             3912..4754
                     /locus_tag="ACG8LA_002808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HFQ0205056.1"
                     /translation="MISIKKVLNSSVVLVEENGKEMIALGKGIGFGQKAGDEISGDKV
                     DKIFLPFEEKKSSQLLELVEEIPIEFFEITRTIVFEAEKGLDKKLNPGVYLTLTDHLH
                     FAVERAQKGVNIANRLYWEIKIYYPKEFQIGKYALTLLNEQYGIDLPKEEASNIAFHL
                     INAQSEDPDSGAGFKYAKMIGGIVNLVRYSLQKDIDTNSIHYARFITHVRFFVERYYS
                     DALLDDGEEEFYNQMWILYPSAMESAAKIKDYIEKVYHKTIPNDEVVYLGVHINRLMK
                     HANG"
BASE COUNT         1605 a          785 c         1028 g         1466 t
ORIGIN      
        1 cgctaatcta attcactgta ttatcatttt ttagtagtat agcacaatta tgaatgcctt
       61 ttctttatat caaataaagt ttatataaaa aacctcatcc tgcaagaaag aaaaaatgaa
      121 cccattcttt ttatactagg tcttaaaaag acagaacatc tgctagaaga tagaagagaa
      181 taagagttat atatgttgga agatattctt agaaaaaaga caaaactttt agaacacgaa
      241 aactatattg aacgaataaa atgaaaaaat gattaaaaaa tcattttatt atttacgttt
      301 acattctaat atgttaaatt gaatataact taaacaggca tgtgactggt aatgcaggca
      361 ggacctaaat aagttgaata acaatgtatg cgtttcaata cacgtttgcc ttgttgtcaa
      421 tttatttagt ttctgcctgt tttttgtgtt gaggatggcc acttcgactc aaaagttcat
      481 cactcaaaaa agaaaagagg gaaacaccat gaattacaaa caaacagcag aagaagtatt
      541 gcagtacatc ggtggggaag aaaacatatc ccatttggag cattgctcaa ctcgtttacg
      601 ttttacgtta aaagacaaca gcaaggtaaa tatgagccag ttagaaaaag tggatggcgt
      661 tatgggcgtt cgccaaaatg tgcaatgcca agtaatcatt ggaaacgatg ttgttgaagt
      721 gtatgatgaa gtgaaagcgt tattaggtga caatgtttca aatactgaag aagcaccaaa
      781 acaaaaacaa aaattaggtt cagttctatt agattttatt atttctattt tccaaccttt
      841 aattcctgcg attgcaggtg gaggagtatt gaagtccttg ttgctactag cttctatctt
      901 agggctgatt agtgaccaat ctcaaaccta tcagatttta aatttggtcg gcggggcacc
      961 gctttatttc ttgcctattc tggtggcaat gactacggct aataaattga aagtcaatca
     1021 attggttgca gtatctgctg tcggtgcatt gatccttcct gaaatgacag ctatgttggc
     1081 ggaaggtgct acattcttat cttttggatt ggataatata gcgtatgcat ctcaagtatt
     1141 cccagccatc ttaactgttt tattttatgc tcaacttgaa aaatggttta caaaagtttc
     1201 accaaaacca attcgtattt tctttgtacc tatgatgagc ttattgatta cagttcctat
     1261 tgctttgttg cttctaggac cattaggtta taatgtagga acagctttct cttctatcat
     1321 tgtgtctttg tacaatcaat ttggatgggt tgcaaccgga gtcttagcag ctgtactgcc
     1381 attaatggtt gtaacgggta tgcataaagc aatgatccct tacgctgttt catccatgag
     1441 tgaattgggt gcagaacttc tttatctccc ggcttcattg gcacacaata tttcagaagc
     1501 tggcgcatgc tttgctgtca gtatcaaaac aaaagacaaa aaattgaaat ctacggctgt
     1561 ttctgcgggt atatctgcat tattcggaat tactgaacca gctctttacg gggtaacgat
     1621 tctgcacaaa cgtgttttat atgccgttat gttttctagc ctgatcgggg gagcatttgc
     1681 aggaatcgtt gcacttcaag cctttgcttt agtgggtcct gggattgcaa gtatcacgat
     1741 gttcgctgac aaagctgacc caatgaatct ggtttgggca tttgcagtat cggggatttc
     1801 atttgtggtt gcttttgctg cagcgttggt tctttataaa gataaagaag ttgtcaatga
     1861 agttgaaact aagatggaaa cggccgttgt ttcagatgct gttctttcaa gtcccgtgaa
     1921 tggaaaagta atctcactat cagaagtaaa agacactgtt ttttctagtg gtatggtagg
     1981 tgatggagta gcaatcattc ctgaagaagg gatattagta gctcctgaag atggagaaat
     2041 cacaatggta tttgaaacga agcatgctat tggtttaaaa acggctaatg gtgcagaact
     2101 tctttttcat attggtattg atactgttca gttagaagga aaagggtttg aggcatttgt
     2161 tcgttctggt gaaaaagtag ccaaaggaca aaagctgatt gcatttgata ttgatttaat
     2221 caaagaagca ggattcgacc ccacagttat ctgtgtggta accaataagg ataattacac
     2281 tatccgttca tttaacctag aaaaattggt aaccaatgat agtgatctct tagctatcag
     2341 tccgatagct taaacacaag atagtgaaaa aaaatatatt gaatgaagga atagaggaga
     2401 atagaataat gacaaacaca acaagttttc caaaaggatt tttatggggc ggcgcgatag
     2461 cagcaaatca agtagaaggt gcttggaatg tagacggtaa aggtctttca gtagcggata
     2521 tggctactta taaaccaaat ttagacaaca aagattttgc tgctcatatg catgtcaccc
     2581 tgcagtctat aaaagaagct agtgaagaca aatctgataa atggtaccca aaaagaaggg
     2641 gcgttgattt ttatcatcac tataaagaag atttagcttt atttgccgaa atgggcttta
     2701 aaaccttgcg cctctctatt gcttggactc gcttgttccc tacaggagaa gagctggaac
     2761 cgaatgaaaa aggggttgca ttttatgaaa acgtctttaa agaaatgcaa cgtttaggaa
     2821 ttgagccgat tgtgacacta tctcattatg aaatgccatt agctttagca gttaaatata
     2881 atggctgggt ggagcgtcga gtaattgatg attttgttcg cttcgctaac gtttgttttg
     2941 atcgcttcgg caaatacgta aaatattggc tgacatttaa tgagatagac agcatccacc
     3001 gtcatccatt tacaacagct ggaattatcc aagagaaaag cgcagaaggt caagaagctc
     3061 aagatatcta tcaagcattg catcatcaat ttgttgcgag tgcgttagtg acaaaagatg
     3121 ctcatgaaaa aattccagga agccaagttg gttgtatgtt aacgaaattg atgacttatc
     3181 cattaacttg cgcaccagaa gacgttgagc tgaccttgaa aaagaactta gaaaataatt
     3241 tttatgcaga tgttcaagtt aagggagaat atcctgctct aatcgaaaag gatttggaaa
     3301 atcggggaat tcagattaaa atggaagatg aagatcgaga aattttaaag aaacataccg
     3361 tagattttgt ttctttcagc tattacatgt ccatggcaga atcagctgat ccaaacgcag
     3421 aacgcacacc gggaaatact gttttagggg ttaagaatcc tcatttgcct tcaacagatt
     3481 ggggctggca aatcgatcca aaaggtttga aaatttcgtt gatcgaactt tatgatcgtt
     3541 accaagtacc gttgatgatt gtggaaaatg gtatgggagc agtcgatcag gtagtagatg
     3601 gtaaaatcca tgatccgtac cgcatcgact actttaaagc acacttccaa caaatgaaag
     3661 aagcaatcga tgaaggtgta gatttgatag cttatactag ctggggacca attgatttag
     3721 ttagtgcagg aacttctcaa atgtctaaac gatatggatt tatttatgtg gatgcagacg
     3781 atgaaggaaa tgggacatat aaccgcttga aaaaggattc gttcaactgg tacaaagaag
     3841 tgatcgaaac aaacggtgca tccttattcg agtagtctcg atctttttaa gcagcgatag
     3901 ggggataatg agtgatttca ataaaaaaag tattgaattc aagtgtggta cttgttgaag
     3961 aaaatggcaa agaaatgatt gcattaggta aagggatagg ctttggacag aaagctgggg
     4021 atgaaatatc aggagataaa gtagataaaa tatttctgcc ttttgaagaa aagaaatctt
     4081 cacaactatt agagttagtt gaagaaatac ctattgaatt ttttgaaatc actcgtacta
     4141 tcgtttttga agcagaaaaa ggattagata aaaaactgaa tcctggagtc tatttaacct
     4201 taacagacca cctgcatttt gcagttgaac gcgcacaaaa aggggtaaat attgcaaacc
     4261 gtttgtactg ggaaataaaa atctactatc ccaaagaatt tcaaattggg aagtacgcac
     4321 tcaccctttt gaacgagcaa tatggaattg atcttcctaa agaggaagcc tcaaacattg
     4381 ctttccattt gatcaatgca caatcggaag atcctgatag cggcgctgga ttcaagtatg
     4441 caaaaatgat cggcgggatc gtcaatttgg tccggtattc gttgcagaaa gatatcgata
     4501 ctaattcgat ccattatgcc cgcttcatta cacatgtacg tttctttgta gaaagatatt
     4561 attctgatgc tttgttggat gatggtgagg aagaattcta caatcaaatg tggatcttat
     4621 acccgtctgc catggaaagc gcagctaaga tcaaagacta cattgaaaaa gtttatcata
     4681 aaacaattcc gaacgatgaa gttgtatacc taggtgtcca catcaatcgg ttgatgaaac
     4741 atgctaatgg gtgagcgctc agtaatacta ttgatgcttt taaaatcttt agagatggat
     4801 tatagtaaaa acaaggtgat ttccagctgt ttgttatcta taagagacat ttaaaaagga
     4861 ttaacgtaag ataataaaaa atct
//
LOCUS       DAZKKZ010000120         4822 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.125, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000120 DAZKKZ010000000
VERSION     DAZKKZ010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4822)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4822)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4822
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.125"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(82..1890)
                     /gene="pepF"
                     /locus_tag="ACG8LA_002809"
     CDS             complement(82..1890)
                     /gene="pepF"
                     /locus_tag="ACG8LA_002809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HFQ0205057.1"
                     /translation="MEVKQLPKREELPENLTWDLTKIFSSDQEFDEKYLELSEELKQS
                     EKHKGTLDQGASQFLNAIEFVLRVYRQTEVIYVYAHLKNDQDTGNTDYQALYARASSL
                     FSKVSEAVSWFEPEILQLSDDQIWQYFKEEPKLEVYRHYIQQIVDNRAHVLSAEQESL
                     LAGAGEIFDASSDTFAVLNNADLVFPTIEGENGEIVQLSHGVYGQLLESTDRRVREAA
                     FKGLYSVYEQFRNTFASTLGTHIKGHNFKAKVRNYSSAREASLSNNHIPESVYDTLVD
                     VVNKHLPLLHRYMELRKRLLEVEKLHMYDLYTPVLGEAPITFTYEEAKEKALEALKPM
                     GEEYMAIVEKAFSERWIDVVENKGKRSGAYSSGSYDTNPYILLNWHDTLDQLFTLVHE
                     MGHSVHSYFTRSNQPYVYGDYSIFLAEIASTTNENILTEYLLETEKDPRVRAYVLNHY
                     LDGFKGTVFRQTQFAEFEHFMHTEDEKGVPLTSEYLSDSYGKLNAKYYGPAVEEDPEI
                     KFEWSRIPHFYYNYYVFQYSTGFSAASALAKKILNQEPEALENYLAYLKAGNSDYPVE
                     VMKKAGVDMTQAAYIEDAMSMFEQRLNELEELIDRL"
     gene            complement(2066..3064)
                     /locus_tag="ACG8LA_002810"
     CDS             complement(2066..3064)
                     /locus_tag="ACG8LA_002810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA family protein"
                     /protein_id="HFQ0205058.1"
                     /translation="MLLAMNEYNKCCFAKHAEKGKKYYCRGCRKRVILKKGKKKCAHF
                     AHQKSDNCSVFSERESKEHLQLKECFMDWLGQSVEPVFLEAYLPRLRQRPDILLANLA
                     IEIQCSRLSHQRFIERTQNYLNNSYQVWWILGNSFLGQSQFSLIEKSCCYYNRKRGVH
                     CWKADLKKQKLYLYHHITETVSGHISFCSSCWTFSSRDLKEIFTSNEIKMNQMKKIEK
                     VSEDGKKWLTRQLIHKQKNTVSIQEQCYLRHKHLLHLSSWIYQKSRFFFYLQEQVFLY
                     RMLYEEALENQKVPDFNSWLCQIKEHKREWLFPMIDEEMVYQQFFNECIHLSSLKK"
     gene            complement(3290..3943)
                     /locus_tag="ACG8LA_002811"
     CDS             complement(3290..3943)
                     /locus_tag="ACG8LA_002811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HFQ0205059.1"
                     /translation="MEMEHINENTIRVLIGHEDLEERGVSFLDLLGNHKEIENFFYSI
                     LEEVDIEEEFRGSEAVTFQVLPKGDGLELFISKNLPDEEISQSEDSTVDSEDVSDFLR
                     QQIIGSDPEEELSGSALEEQERQATFAFEDFEQVIQLATDVELESAWTDLYLFEERYY
                     LVVHFWMENLNQADVENQIARILEFAEKSDRTPETLNEYGQCLMARNAIERTKFYFV"
     gene            complement(4275..4673)
                     /gene="spxA"
                     /locus_tag="ACG8LA_002812"
     CDS             complement(4275..4673)
                     /gene="spxA"
                     /locus_tag="ACG8LA_002812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator SpxA"
                     /protein_id="HFQ0205060.1"
                     /translation="MLTLYTSPSCTSCRKARAWLQEHQIPFVERNIFSEPLNSSELKA
                     ILQMTEDGTEEIISTRSKVFQKLNMDLDDLPLQELLELVQNNPGLLRRPIMIDDKRLQ
                     VGFNEDEIRRFLPRDVRQLELRQAQLMAGL"
BASE COUNT         1419 a         1008 c          748 g         1647 t
ORIGIN      
        1 taaaaaaata cgtcgactcc cttacaagag agccgacgta tttttttcgt ttctattcga
       61 gaaaatcaaa aatagaaagc cttataaacg atcgatcaat tcttctaatt catttagacg
      121 ttgttcaaac atcgacattg catcttcaat atatgcagcc tgtgtcatat caactcctgc
      181 ttttttcatt acttccacag gataatcgct gttacctgct tttaggtaag ccaagtagtt
      241 ctctagtgcc tctggttcct ggtttagtat tttcttcgcc agtgctgaag cagcagaaaa
      301 gccagtcgag tattggaaaa catagtaatt ataataaaaa tgcggtatcc gtgaccattc
      361 gaatttaatt tctgggtctt cttcgactgc tggaccataa tattttgcat tcaatttacc
      421 ataactatca cttaggtatt cactagtcaa tggcacacct ttttcatctt ccgtatgcat
      481 gaaatgctcg aattcagcga attgtgtctg gcggaaaact gttcctttaa acccatccaa
      541 gtaatggttg agtacataag cccgtacacg agggtctttt tctgtttcca ataaatactc
      601 cgttaggata ttttcattcg ttgtcgaagc aatttctgct aaaaagatgg agtagtcgcc
      661 gtacacataa ggctggttcg aacgagtgaa ataactatga acactatgtc ccatttcgtg
      721 gacaagcgta aatagctgat ccagcgtatc atgccaattc aataaaatat atggatttgt
      781 gtcatagctt cccgaagaat aagcaccgct tcgtttccct ttattttcga caacatcgat
      841 ccaacgttca gagaatgctt tttctacgat ggccatgtat tcttcaccca ttggtttcag
      901 tgcttctaaa gctttttctt ttgcttcttc gtacgtaaag gtaattggag cttcccctaa
      961 gaccggtgta taaagatcat acatgtgcag tttttccact tctaataaac gtttccgtaa
     1021 ttccatgtat cgatgtaaca aaggcaaatg cttgtttacc acgtctacca aagtatcgta
     1081 tacactttca ggaatatgat tattgctcaa agacgcttct ctggcagagc tgtaattacg
     1141 gactttcgct ttaaaattat gtccttttat atgtgtgcct aaagtagaag caaatgtatt
     1201 tctaaattgt tcgtaaacac tgtacaaccc cttaaatgct gcttcgcgca cccttcgatc
     1261 cgtgctttct agcaactgac catacacgcc atgagataat tggactattt caccattttc
     1321 tccttcaatc gttggaaaaa ctagatctgc attattcaaa acagcaaatg tatcacttga
     1381 agcatcaaag atttcacctg ctccagcaag aagagattcc tgctcagcag ataagacatg
     1441 ggctcgatta tctactattt gctggatata atggcgatag acttccaatt ttggttcttc
     1501 tttgaaatat tgccaaatct ggtcatctga caattgcaat atttctggtt caaaccagga
     1561 aacggcttca ctaactttcg aaaacagact gcttgctctt gcataaagcg cttggtaatc
     1621 tgtatttcca gtgtcttgat cgtttttaag gtgcgcatat acataaatga cttcagtttg
     1681 gcgataaacc ctcaatacga attcaatcgc atttaaaaat tgagaagcgc cttgatcaag
     1741 tgttcctttg tgtttttcag attgttttaa ctcttctgat aattccaaat atttctcatc
     1801 aaactcttgg tcgcttgaaa agatcttggt caagtcccaa gttaaatttt caggcaattc
     1861 ttctcgtttt ggcaactgct ttacttccat gaaatccact ccttttcttc ccttagctct
     1921 atctatcaaa atagatcata gtctaacatc cacatgtcac agcatctaac ttttctactc
     1981 attcatgtgt ctgcttccat caattttagc ataactaaat cttgttttac atagaaaacc
     2041 gattcctagc ctatttttat acttactatt ttttcaaaga agacaagtgt atgcattcgt
     2101 taaaaaactg ctgatagacc atctcttcat caatcatagg aaaaagccat tcccttttat
     2161 gttcttttat ttggcaaagc catgagttga aatcaggaac tttctggttt tccaaggctt
     2221 cttcgtacaa cattcgataa agaaaaacct gttcttgtaa ataaaagaaa aaccgacttt
     2281 tttgatagat ccacgatgat agatgcaaaa gatgtttatg acgcaagtag cattgttctt
     2341 gtatggatac tgtattcttt tgcttgtgaa taagttggcg tgtcagccat ttcttcccat
     2401 cttcactcac tttttctatt tttttcattt ggttcatttt aatttcgtta ctagtgaata
     2461 tttctttaag gtccctacta gaaaaagtcc agcagctact gcaaaaggaa atatgccctg
     2521 atacagtctc tgtaatatga tgatacaaat aaagcttttg tttcttgaga tcagctttcc
     2581 agcaatgcac tcctcttttt ctattatagt agcagcaact tttttctatc aatgagaatt
     2641 gcgattgtcc aagaaaagaa ttaccaagta tccaccatac ttggtaactg ttattcaaat
     2701 aattttgggt tctttcaata aatctctggt gagacagtct agaacattgg atttctattg
     2761 ctagattcgc caacaaaata tccggccttt gccgcaacct cggcaaatag gcttccaaaa
     2821 atactggttc tactgactgt cccagccaat ccatgaagca ttcctttaac tgtaagtgct
     2881 cttttgattc tctttcacta aagaccgaac agttatctga tttttgatgg gcaaaatgag
     2941 cacatttttt ctttcccttt ttcaaaatca ctctttttcg acagccacga caataatatt
     3001 tctttccttt ttctgcatgt ttagcaaaac agcacttatt atattcattc attgcaagca
     3061 gcatttttct ccctctgaac ttatttacgt ctaagaattt atttacacga aaaaagaggg
     3121 cgtgaaaaag ctattctgca tcaagtaata agaacagcta aacaaaaata gttcccaata
     3181 tttttcgttt ggttgggctt gttaccgcag atgcaagctt ttgaacacat ttatacgaaa
     3241 aaaagactgc gacacaattt ttgtcacagt ctcttactat aatgctgatt tatacaaaat
     3301 aaaatttcgt tcgctcgata gcattacgcg ccatcagaca ttgtccatat tcattcaatg
     3361 tttctggtgt acgatcgctc ttttcagcaa actccaaaat tcgagcaatc tgattctcta
     3421 catccgcttg gttgagattt tccatccaga agtgaacgac taggtaatag cgctcttcga
     3481 ataaatacaa atcagtccaa gcagactcta gttcgacatc tgttgcaagt tggatcactt
     3541 gttcaaaatc ttcaaaagca aaagttgctt gtctttcctg ttcttctagg gcgcttccag
     3601 ataattcttc ctccggatcg ctgccaataa tctgctgacg aagaaagtca ctcacatctt
     3661 ctgaatcaac agtagaatct tctgattgag aaatttcttc atccggaaga tttttactga
     3721 taaacagttc taatccgtct ccttttggca aaacttggaa agtgacagct tcgcttcctc
     3781 ggaactcctc ttcgatatca acttcttcca aaatactata aaagaaattt tcgatttctt
     3841 tgtgattgcc aagtaaatcc aaaaatgaaa cgccccgttc ctctaaatct tcatgaccaa
     3901 ttagtacacg gatcgtattt tcattaatat gttccatttc cattttgcta cacctcactt
     3961 tgccacaatg tttaatatag attcattgta gcgaaatcag cttaaatgta aagaaaaaaa
     4021 atctcgctgt taagcgaatt taataaaacc agcggatttt tcaacctttc aagctatctt
     4081 atttaactat aacatttttg gcagacgaat actatatagc cgacttttca gctaattttc
     4141 cctctctatt tttcgtgcaa tcatcatctt ctactacctt tttatacatc taatcaagaa
     4201 tactttttgt aaaaacaaaa aaacttggaa aaactatctt tgtaatagtc ttttccaagt
     4261 ttcgtattat ccttctataa tccagccatc aattgtgctt gacgtaattc taattgtcgt
     4321 acatcgcgcg gtaggaaccg acgaatttca tcttcattaa aaccaacttg cagacgttta
     4381 tcatcaatca tgattggacg gcgaagcaat ccaggattgt tttgcacaag ttccaataat
     4441 tcttgtaacg gcagatcatc taaatccatg ttcagttttt ggaatacttt ggaacgtgtc
     4501 gagatgattt cttctgttcc gtcttctgtc atttgtaaaa tcgcttttaa ttcagaactg
     4561 ttcaatggtt ctgaaaaaat attacgttca acaaatggaa tctgatgttc ttgcaaccac
     4621 gcacgagcct ttctgcagga agtacaactt ggggaagtat ataatgttaa caacgtgcac
     4681 cactcctttt cgtgataaga atcacttttt tgtaacagaa gatcataata atctcccatc
     4741 tgtttctatt atacataatc aacttttaaa tagctacctt tttttcataa tttttttaaa
     4801 aaaatgaaag ttatctaagg tt
//
LOCUS       DAZKKZ010000121         4776 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.126, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000121 DAZKKZ010000000
VERSION     DAZKKZ010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4776)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4776)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4776
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.126"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(207..1169)
                     /locus_tag="ACG8LA_002813"
     CDS             complement(207..1169)
                     /locus_tag="ACG8LA_002813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004233175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFQ0205061.1"
                     /translation="MVAKLTDVAELAGVSPTTVSRVINNKGYLSEKTKQKVHEAMKTL
                     GYKPNNLARGLQGKSPQLIGLIFPNISNIFYSELIEYLEIELFKHGYKTIICNSQNDP
                     AKEREYIEMLEANQVDGIISSSHNLGIADYERVRAPIVAFDRNLAPNVSIVSSDNFEG
                     GKLAAKTLQKNGCQNTIMITGNDNTDSPTELRALGFSFQNPNGKIFKIPNNLSTIRRE
                     MEIKSTIINHKPDGIFVSDDLTAILTMKIAHQLKLNIPEDLKIIGYDGTSFIEKFFPQ
                     LTTIRQPIDEIASLIVDILLKKIKGEKTNKDYILPISILSGGSI"
     gene            complement(1171..2610)
                     /locus_tag="ACG8LA_002814"
     CDS             complement(1171..2610)
                     /locus_tag="ACG8LA_002814"
                     /EC_number="3.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004564 - beta-fructofuranosidase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="HFQ0205062.1"
                     /translation="MNLPREIRYRAYSDWTKDEMDKIKDNVKRSPWRASYHIEPKTGL
                     LNDPNGFSFFNGKYTLFYQNWPFGAAHGLKEWVHNESDDLVHFHVTGAELLPDTKRDS
                     HGAYSGSAYEIEGNLFLLYTGNVRNENWERDTLQIGAWMDKDYNITKGENVLIHKPAD
                     VTDHFRDPQMFNYEGQLYAIVGAQNLEKSGFIKLYKADDNNVETWEEVGNLDFGGTGS
                     EYMIECPNLVFVDKKPVLIYCPQGLDKSELNYGNIYPNTFKICQSLDIEKVKLVGASE
                     IQNLDYGFEAYATQGFNTPDGRALIVSWIGLPDIDYPTDKYDYQGAMSLVKELSIKDG
                     KLYQYPVEAITSLRASSEQFTAKAETNNTYELELTFPPNQKSELLLFSDSKGNGLSLI
                     VDTKEGKIILDRSKAGIQYATDFGTIRECSIDTKETTANIFVDNSIIEIFINKGEKVF
                     TSRVFPENHQNGIQIKSGEPTGKYFELKY"
     gene            2795..4741
                     /locus_tag="ACG8LA_002815"
     CDS             2795..4741
                     /locus_tag="ACG8LA_002815"
                     /EC_number="2.7.1.211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-specific PTS transporter subunit IIBC"
                     /protein_id="HFQ0205063.1"
                     /translation="MNYSKVASDVIQAVGKDNLIAAAHCATRLRLVLKDDTKVNQKAL
                     DENPDVKSTFKIDGQYQVIIGAGDVNFVYDELIKKTGLSEISTDDLKQIASKDKKFNP
                     IMALIKLLSDIFVPIIPALVAGGLLMALQNFLTAAGLFGPKSIEEMYPAIEGISSMIQ
                     LMSAAPFMFLPILVGISAAKRFGANQFLGAAIGMIMTTPDLGGSTEYWNIFGYHVSQT
                     NYAYQVIPVLAAVWILSILEKFFHKKLPSSIDFTFTPLLSVMITGFLTFTVIGPVMLL
                     LSNGITDIIVWLYNTTGFIGMGIFGGTYSLIVMTGLHQSFPAIETQLLSAWTNGIGHG
                     DFIFVVASMANVAQGAATFAIWFLTKNSKTKSLASSAGVSALLGITEPALFGVNLKYR
                     FPFFCALIGSGIATAVAGLLKVVAVSLGSAGFLGFLSINATSIPFYVLCELISFVVAF
                     AITYFYGKTKAAGIFKAEEIAEQTPVNSSKVATTDPISTDVESTQTKVSSETIVSPIS
                     GKVISLSSVNDPVFSSEAMGKGIAIKPNGNTVHSPVDGTIQLTFETGHAYGIKSNNGA
                     EVLIHIGIDTVSMGGKGFTQKVTTNQKVRKGDILGAFDRSMIEKEGLDDTTMIIVTNT
                     SDYSEVNIVAENTVTEGTDLLEIK"
BASE COUNT         1516 a          819 c          790 g         1651 t
ORIGIN      
        1 cgtccaattt cgtaaaacaa ccgtaacagt tgtgtaaaaa tatcatttta gagcatgaaa
       61 aaaggagtgg atttctccac tccaaaaaag tctaactttt gggggtcact acaagttgac
      121 aactcctttt tgtttacaaa tcaattggat atctacaaat tgtattttct aacgaatttt
      181 atagacatta aaaaattaat ttaacgttaa atacttcctc cagaaagtat tgagattggt
      241 aaaatataat ccttatttgt cttttcgcct ttaatttttt tcagaagaat atcaacaata
      301 agacttgcaa tttcatcaat tggttgtctt attgttgtca attgtgggaa aaatttctca
      361 atgaaagagg taccatcgta tccaataatt tttaaatctt ctgggatatt aagtttaagt
      421 tgatgagcaa ttttcatagt gagaatggct gttaaatcat cagaaacaaa aataccatct
      481 ggtttgtgat ttataatagt tgactttatt tccatttcac gacggatagt agacagatta
      541 ttaggaattt tgaaaatttt tccatttgga ttttgaaaag aaaaacctag tgcacgtaat
      601 tctgtgggag aatccgtgtt atcatttcct gtaatcataa tggtattttg acaaccattt
      661 ttttgtaaag tcttagctgc aagttttccc ccttcaaagt tatctgaaga aacaatggaa
      721 acattaggag ctaaatttct atcaaaagca acaataggtg ctctcacacg ctcataatca
      781 gcaattccaa gattatggct tgatgagatt atgccatcaa cttggttggc ttcaagcatt
      841 tcaatgtatt ctctctcttt agcaggatca ttttgactat tgcaaataat cgttttatat
      901 ccatgtttaa ataactctat ttcgagatac tcaatgagtt cagagtaaaa gatattacta
      961 atattaggaa aaataagacc aataagctga ggtgactttc cttgaagtcc acgtgctaaa
     1021 ttatttggtt tataaccaag agttttcata gcttcatgaa ctttttgttt tgttttttct
     1081 gataaatatc ccttattatt aatgacgcgt gaaacggttg ttgggctaac tccagctaat
     1141 tcagcgacat cagttaattt tgctaccatt ttaatatttt aattcaaagt attttccagt
     1201 aggttcgcct gatttgattt gaataccatt ttggtgattt tcagggaata cacgactagt
     1261 aaacactttt tctcctttat taataaaaat ctcaatgatt gagttatcta caaaaatgtt
     1321 agcagttgtt tctttagtat caattgagca ttcacgaatc gtaccaaagt cagtggcata
     1381 ttgaatgcct gctttgctgc gatctaaaat aatttttcct tctttggtat ctacaatcaa
     1441 gctaagtcca tttcctttac tatcagagaa aagaagtaac tccgatttct gatttggagg
     1501 aaaagttagt tcaagctcat aagtattatt tgtttctgct tttgctgtaa attgttcaga
     1561 actagcacgt aatgatgtaa tagcttctac tggatattgg taaagtttac catcttttat
     1621 tgaaagttct tttacaagac tcattgctcc ctgataatca tacttatcag ttggataatc
     1681 gatatcaggt agtccaatcc aactgacaat cagagcacga ccatcaggag tattgaatcc
     1741 ttgagtcgca tacgcttcaa atccataatc aagattttga atttctgaag cgcccacaag
     1801 ttttactttt tctatgtcaa gcgattgaca gatcttaaaa gtattcggat agatattccc
     1861 ataatttagc tcagatttat ccaacccttg aggacaataa atgagaacag gttttttgtc
     1921 tacaaatact agatttggac actcaatcat gtattctgaa ccagtgccgc caaaatcaag
     1981 gttgccaact tcctcccatg tttccacgtt attgtcatcc gctttgtaaa gtttgataaa
     2041 gcctgatttt tctaaatttt gtgctccaac aatcgcatac aattgtcctt cataattaaa
     2101 catttgtgga tcacgaaaat gatcagttac atcagcaggt ttatgaataa gaacattctc
     2161 acctttcgta atgttgtagt ctttatccat ccatgctccg atttgaagtg tatcacgttc
     2221 ccaattttca tttcgaacgt ttcctgtata gagtaagaat agattcccct ctatttcata
     2281 tgcagaaccg gaataagcgc cgtggctatc tcgttttgtg tctggaagaa gttctgctcc
     2341 tgttacatga aaatgaacta aatcatctga ttcattgtgt acccattctt tcaacccatg
     2401 agcagctcca aatggccaat tttgataaaa aagcgtatat tttccgttaa aaaaagaaaa
     2461 accattagga tcgtttaaca atcctgtttt aggttcgata tgatagctag cacgccaagg
     2521 tgatcgtttt acattatcct taattttatc catctcatct ttagtccaat cagaataagc
     2581 acgatatcgt atttctcgag gtaagttcat attttactcc ttcaatttat ctttttacaa
     2641 ctagtatggt aaacgttttc cgttgaaaaa tcaatcattt catttaaaaa aataaactat
     2701 atgacaaacg tttgacatat ttttaagata tgctaaaata aatttgcatt tcagtgaacc
     2761 gttttcacgt aaaaataaaa aaggagtgat tcgaatgaat tacagtaaag tagcttccga
     2821 cgtaatacaa gcggtcggaa aagataacct tattgcagct gcacactgcg ctacacgtct
     2881 tcgtctcgta ctaaaagatg acacgaaagt gaatcaaaaa gctttagacg aaaatccaga
     2941 tgtgaaaagc acatttaaaa ttgatggaca atatcaagtg attatcggtg caggtgatgt
     3001 taatttcgtt tatgacgaac ttatcaaaaa aactggactt tcggaaattt caacagatga
     3061 tttaaaacaa attgctagta aagataaaaa attcaacccc attatggcat taattaaatt
     3121 attatcagat atttttgttc caattatacc tgcccttgtt gcaggtggtt tattaatggc
     3181 attacaaaac tttttaacag ctgctggact ttttggacca aaatcaattg aagaaatgta
     3241 tcctgcgatt gaaggtattt cctcaatgat ccaactgatg tccgctgcac cattcatgtt
     3301 cttaccaatt ttagtaggta tttcagctgc taaacgtttt ggagcaaacc aatttcttgg
     3361 tgctgcaatt ggtatgatca tgacaacacc agatcttggt ggctcaactg aatattggaa
     3421 tatttttggt tatcatgttt cacaaacaaa ctatgcttat caagttattc cagttttagc
     3481 agctgtttgg atattatcta tattagaaaa attctttcat aaaaaattgc catcatctat
     3541 tgactttaca ttcacgccat tattatcagt aatgattact ggatttttga ctttcacagt
     3601 tattggccct gtaatgttat tgttgtctaa tggaattaca gacattattg tttggctata
     3661 taacactact ggatttattg gaatgggtat ttttggagga acatattcac ttatagtcat
     3721 gactggttta catcaatcat ttccagctat tgaaactcaa ttactttcag cgtggacaaa
     3781 tggtatcgga catggagact ttatctttgt agttgcatct atggcaaacg ttgctcaagg
     3841 tgctgcaaca tttgccattt ggttcttaac taaaaattct aagacaaaaa gtcttgcttc
     3901 ctctgcgggt gtctcagcac ttcttggaat tacagagcct gccttgttcg gagttaactt
     3961 aaaataccgc tttccattct tttgtgcttt aattggttca ggaattgcta cagcagtagc
     4021 aggattactt aaagtagttg ctgtttcact tggttcagca ggtttcttgg gatttctttc
     4081 aattaatgca acatctattc cattttacgt attgtgtgaa ttgattagct ttgtagttgc
     4141 ttttgcaatt acttacttct acggtaaaac aaaagctgct ggtatcttta aagcagaaga
     4201 aattgctgaa caaacaccag ttaattcttc aaaagtagca acaacagatc caatatctac
     4261 tgatgttgaa tcaacacaaa caaaagtttc atcagaaaca attgttagtc ccatttctgg
     4321 taaagtgatt agtctttctt cagtaaatga tccagtcttt tcatcagaag ctatgggaaa
     4381 agggattgcc attaaaccaa atggaaacac ggtccattct ccagtagatg gtactattca
     4441 actcacgttt gaaactggac atgcttatgg tattaaatca aataatggtg ctgaagttct
     4501 aattcatatt ggtattgata ctgtatcaat gggaggaaaa ggatttacac aaaaagttac
     4561 tactaatcaa aaagttagaa aaggcgatat tcttggagca tttgaccgtt caatgattga
     4621 gaaagaaggt cttgatgata caacaatgat tattgtgacc aatacttcgg attattcaga
     4681 agtaaatata gtagctgaaa atacagtcac tgagggtact gatttacttg aaatcaaata
     4741 aatatatttc cctgagtaaa gatggaattt tctttc
//
LOCUS       DAZKKZ010000122         4735 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.127, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000122 DAZKKZ010000000
VERSION     DAZKKZ010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4735)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4735)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4735
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.127"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(19..1017)
                     /locus_tag="ACG8LA_002816"
     CDS             complement(19..1017)
                     /locus_tag="ACG8LA_002816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4767 domain-containing protein"
                     /protein_id="HFQ0205064.1"
                     /translation="MKKWLLLLIGMGILFTGCTSENTRTKATIETDTTIETKKSKTQS
                     TEQTTTEMKQSVETSASSITESSSEEVKNTLWDTNKASKLETFVTQWGKTLGQEYKSY
                     NLQNNVSLYGTPLPQAVINGDWKMAINEAPVTVQWSEDGTGHADFNLVAVYSDVETGE
                     YLGQHVYFFGFQNGQPKVYLTQQNQGNENNYLYFNETQNQQLKQGFSDIVNGQTPQTP
                     VVEESTQQATTTTTQSTSSSGISSWEAAKESVLNNKALWLYDSPDKNVSNTNLISTNE
                     YMKDLMQDENGSYYSINIVTDDDGNTTMAGGKQFRVYTDGRISQRIGMTNNFQMIK"
     gene            complement(1092..1388)
                     /locus_tag="ACG8LA_002817"
     CDS             complement(1092..1388)
                     /locus_tag="ACG8LA_002817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0205065.1"
                     /translation="MAKLIVLGGLIYGGYWLYQYMLAHPNIDKGKVIKTVGVIIVGLI
                     ALTKKNNTNSPKIMRTYRCRGCGREISTSFNPSESPQGRDRCHTGYRHYWERID"
     gene            complement(1381..1674)
                     /locus_tag="ACG8LA_002818"
     CDS             complement(1381..1674)
                     /locus_tag="ACG8LA_002818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mor transcription activator family protein"
                     /protein_id="HFQ0205066.1"
                     /translation="MEIDETCLSNSYKSMNDFFEEMELDSELLYQFYLAFRGQQISFP
                     MKMYDRELVRKRIENMIEQEKTVDIRQLTEVYGFSARWIQKVIKQKERRRVHG"
     gene            complement(1820..2371)
                     /locus_tag="ACG8LA_002819"
     CDS             complement(1820..2371)
                     /locus_tag="ACG8LA_002819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1643 domain-containing protein"
                     /protein_id="HFQ0205067.1"
                     /translation="MIEKELVTTQTEVWRDPHHTHRYVFKRQWAIKGKEAEDKLAVVI
                     TIRPTDTEPFTNDLSMLLIEKNIRQLGFTGFIAVNLFSYTKAKSPRVFLRGNDEQSLE
                     ILTTVFTEKKINTIIFACGSITATSQVAYEQAKTIYDQLSAKQKKMTKVLINAEGKLS
                     HPLSIHVRNEWQLADSQLLFQEK"
     gene            complement(2545..2844)
                     /locus_tag="ACG8LA_002820"
     CDS             complement(2545..2844)
                     /locus_tag="ACG8LA_002820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4'-phosphopantetheinyl transferase"
                     /protein_id="HFQ0205068.1"
                     /translation="MLETAIEVLEKCAQLVTASEEWGYESVTMEKEEIEMGMLPEDVH
                     LPRLVMTHLYIYCAPEDGKDYVVYFITDITSQREFVRGLLVEGRLVWSQIGGTDE"
     gene            complement(2871..3146)
                     /locus_tag="ACG8LA_002821"
                     /pseudo
     CDS             complement(2871..3146)
                     /locus_tag="ACG8LA_002821"
                     /inference="COORDINATES: protein motif:HMM:NF017894.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
     gene            3484..4167
                     /locus_tag="ACG8LA_002822"
     CDS             3484..4167
                     /locus_tag="ACG8LA_002822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HFQ0205069.1"
                     /translation="MTTEHFDLANPVTKVDDIPDYEMYSQTIDSLNKRFGNRVLKGIK
                     IGYIASEKDRIIDYLADKDYDLKLLSVHHNGQFDYLDDEVKDMDPAIVIPQYFAQLSE
                     ALVVIEADVFAHFDYGFRVFGLSVAEFKQYEAQFLPILDQVIKNKLAFELNAKSAYLY
                     DNLALYEYVIDLYLSRGGTLFSVGSDGHYLEHFRFHFDDLFALLKANGVTELAIYQKG
                     KRIMVPLPV"
     gene            complement(4204..4701)
                     /locus_tag="ACG8LA_002823"
     CDS             complement(4204..4701)
                     /locus_tag="ACG8LA_002823"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFQ0205070.1"
                     /translation="MNNQITLAYLDYDDLDALQVVSVVSFYESFIDGADPLDMQGYLQ
                     TQLTTEILAVELAQSTSKFIGIKDHQILIGYMKVNDEKDAIEIQRLYLLKDYQNKGLG
                     QRLLDEANRYAKTKQKRYLRLTVYEKNHAGIRFYERHGFKKIGIKHFPLGKQDRICPI
                     LEKEI"
BASE COUNT         1404 a          906 c          694 g         1731 t
ORIGIN      
        1 gataaataat attttcaatt atttaatcat ttgaaaattg ttagtcattc caatacgttg
       61 agaaattctt ccatctgtat aaacacgaaa ttgttttcca ccagccatgg tcgtgtttcc
      121 atcatcatcc gttacaatat taattgaata gtagcttcca ttttcatctt gcattagatc
      181 tttcatatat tcatttgtgc taattaaatt agtatttgat acatttttat caggagaatc
      241 atacaaccat aaagctttat tatttagcac agattcttta gcagcttccc aacttgaaat
      301 tcctgaacta cttgtagatt gtgtcgttgt agttgttgct tgttgagtag attcttctac
      361 tactggtgtt tgaggagttt gtccattcac aatatcactg aaaccttgtt ttaactgttg
      421 attttgagtt tcgttaaagt acagataatt attttcatta ccttgatttt gttgcgttaa
      481 ataaacttta ggttgtccat tttgaaaacc gaaaaagtaa acatgctgcc ctaaatattc
      541 tccagtttct acatcagaat aaactgctac taaattgaaa tctgcatgac cagttccatc
      601 ttctgaccat tgtacggtaa ctggtgcttc attgattgcc attttccaat cgccattaat
      661 cacggcttgt ggtaaaggag tgccatacag acttacatta ttctgaagat tgtagctttt
      721 atattcttga cctaatgtct ttccccattg tgtgacaaaa gtttctaatt tggaagcttt
      781 attcgtatcc cacaaagtat tcttaacctc ttcagaagaa gattcagtga ttgaacttgc
      841 acttgtttcc acagattgct tcatttctgt tgtagtttgt tcagttgatt gcgttttact
      901 ttttttagtc tcaattgttg tatcagtttc tatagtcgct ttagtcctcg tattctcaga
      961 tgtacaacca gtgaataaaa ttcccattcc tattagtaat aacagccatt ttttcattat
     1021 atttccccct ttcaatttct ccctcacgta cttattctat cagacaatta attgatctaa
     1081 atggtaatct tttaatcgat tctttcccaa taatgtcgat agcccgtatg gcagcggtct
     1141 cttccttgag gactctcaga tggattaaaa ctagtagaaa tttcccttcc acatcctcta
     1201 cagcgataag ttctcattat ttttgggcta ttagtattat ttttcttagt tagagctatg
     1261 agtccaacta tgattacccc aactgtctta attacttttc ctttatctat attcggatgc
     1321 gcaagcatat attgatataa ccaatatcca ccgtaaatta aaccacctaa tacaatcagc
     1381 ttagccatgt actcgtctcc tttctttttg tttaattact ttttgaatcc atcttgcaga
     1441 gaaaccataa acttctgtca attgacggat atctacagtt ttttcctgtt ctatcatgtt
     1501 ttcgattctt tttctaacta actcacgatc gtacattttc attggaaaag aaatctgttg
     1561 ccctcgaaaa gcaagataaa attgatagag caattctgaa tccagttcca tttcctcaaa
     1621 aaagtcattc atacttttat aagagttact caaacaagtt tcatcaatct ccatctacac
     1681 accccctgtt attttttaca taatgaaaat agcatattac tgggtacatt gataattcat
     1741 ataacatgta tcatcacatg tatttttaaa gtcaaaaagc atgtaaaact acttataagt
     1801 aacatgagaa aataaaatgt tatttttctt gaaataataa ttgactatct gccaattgcc
     1861 attcattacg aacatgaata cttagtgggt gggataactt accttctgca tttatcaata
     1921 ctttggtcat cttcttttgt ttcgcactca attgatcgta aatagtcttt gcttgttcat
     1981 aagccacttg actcgtcgct gtaatcgaac cacaagcaaa aataatggta ttgattttct
     2041 tttctgtaaa aacagtcgtt aatatttcca aagattgttc atcatttcct cgaagaaata
     2101 cccgaggact tttcgctttt gtgtacgaaa aaagattcac agcaataaaa ccagtaaatc
     2161 ctaattgtcg gatattcttt tcgattaata acatactcaa atcattcgta aatggttctg
     2221 tatctgttgg acgaatagta atgactactg ctaatttatc ttccgcttct tttcctttga
     2281 tcgcccattg tcgtttgaaa acatagcgat gggtatgatg aggatctcgc caaacttctg
     2341 tttgtgtggt cactaattct ttttcaatca tctctttttc tcctatgcta ttttttgttc
     2401 aagcacttca attaccattg ccgttataag tgtcaatact agttgaaaat atttcatatt
     2461 ctttctcctt ttttcttcag aatttgatga atcgcggtaa ggatatcttc taaacatttc
     2521 gcaatcattc tcaaataatc gatcttattc atccgttcct ccaatctgac tccaaaccaa
     2581 tcgtccttct accagtaacc cacgaacaaa ttctcgctgg ctggtaatat ctgtaatgaa
     2641 ataaactaca tagtcttttc catcttctgg tgcgcaataa atataaagat gtgtcatcac
     2701 taaacgtggt agatgaacat cttcaggaag catacccatt tcaatttcct ctttttccat
     2761 cgtaacggat tcatagcccc actcttcaga agcagtgacc agctgtgcac acttttccag
     2821 tacttcgata gccgtttcta acaagtcctt tcgttccttt cttttagata ctagtattct
     2881 tctggtaata acatcgtttg atactcaccc gaatcaatgg cccatatttt ttgagacact
     2941 gatttcaaac gaagcttagg tgaaatcaga tactcttttc tttcttccgg ttcttcttga
     3001 cgatgaacca acttttgatt tcctttttcc gtagaaaatt caaaaatttg aagatagtct
     3061 aaaggaaatt gcttttgaac gttttgatcg attagattcc aacataaagc ttgtaattcc
     3121 accggcaaac tgtccattac tccctttgtg acataacgtt atcctttatt ttgaaacatt
     3181 tcttttccct cctttgccat aaaaatagcc caatcttcta ttaaagaaga ttgggcttca
     3241 tggatataat atatatttgt aaataaagtt aattcagtta taattatcaa aactacacaa
     3301 ttattaaagt ttttcatatc tctttgttta gtaagttttt ctaaatctta acccgtggtg
     3361 ctagttaatt ttttcctaga ggaaaatgtc taaacatgtt ggtaaatcaa caaaaaaacg
     3421 catatagtag tctcaaaact cccaagaaat gaggactatt taacaaacta cgatggttac
     3481 gtcgtgacaa ctgaacattt tgacttagcc aatcctgtta ctaaagtcga tgatatcccc
     3541 gattatgaaa tgtacagtca aacaatcgat agcttaaata agcgttttgg caatcgtgtt
     3601 ttaaaaggca tcaaaatcgg ttacatcgct tctgaaaagg atcggatcat cgactattta
     3661 gccgataaag attacgattt aaaattactc agtgtgcatc ataatgggca atttgattat
     3721 ttagatgacg aagtcaaaga tatggatcct gctattgtga ttcctcagta ttttgcacaa
     3781 ctttcagaag cactagttgt tatagaagca gatgtctttg ctcattttga ctatggtttt
     3841 cgggtatttg gtctatccgt tgctgaattt aaacaatatg aagcgcagtt tttaccgatt
     3901 ctagatcaag taatcaaaaa taaattggca ttcgaattaa atgctaagag cgcttacttg
     3961 tatgacaatt tagcgttata tgaatatgtc atcgatttat atctttcacg tggtggtacc
     4021 ttgtttagtg ttggatcaga tgggcattac cttgaacatt tccgtttcca tttcgatgat
     4081 ctttttgctc tgttaaaagc aaatggtgtg acggaattag cgatttatca aaaaggaaag
     4141 cgaattatgg ttccattacc agtctaaaaa aacgtcctca gcatcaaaag tgaggacgtt
     4201 tttttagatt tctttttcta aaatcggaca aatacgatct tgttttccta aaggaaaatg
     4261 tttgatcccg atttttttaa atccatgacg ttcataaaaa cgaatacctg catgattttt
     4321 ttcataaaca gtcaaacgta aataacgttt ttgtttcgtt ttagcataac gattcgcttc
     4381 atcgagtaac cgttgcccta accctttgtt ttgataatct ttgagcagat agagccgttg
     4441 aatctctata gcatcttttt catcattgac tttcatataa ccaatgagta tttgatgatc
     4501 cttaatacca ataaatttac tggttgactg tgccaattct actgccaata tttcagttgt
     4561 caattgtgtc tgtaaatatc cttgcatatc aagtggatct gcgccatcga taaacgattc
     4621 ataaaaactg acaacactta caacttgtaa agcatctaga tcatcataat ctaaatacgc
     4681 tagtgtgatt tgattgttca tctaactcct ccttttgaca tagtatacta taaat
//
LOCUS       DAZKKZ010000123         4590 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.128, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000123 DAZKKZ010000000
VERSION     DAZKKZ010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4590)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4590)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4590
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.128"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            148..1137
                     /locus_tag="ACG8LA_002824"
     CDS             148..1137
                     /locus_tag="ACG8LA_002824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /protein_id="HFQ0205071.1"
                     /translation="MKKKKQDLINGTFREKKKNLKKVVAFSDNRISPKMRELMTGCGS
                     YLEFIATIDKEKKKLVQAHFCKNRFCPLCAWRKARKDSMMLSIMMQAIAEEKQYQFIF
                     MTLTTPNVKAECLNDEIDLFNHALKKMFMRKRVKTSIKGYVRKLEITYNKKRNDYNPH
                     FHLILAVNKSYFTDKDYYIKQSEWLDLWREVTGKTGINPDGTDEITQLDIRKVKGFQQ
                     EKAVQEVAKYSAKDFELTESQEVFDTFYHAMKGRQLITFNGVFKEYKKKYESGDLDRY
                     KKKDENEYFWFLTASWMRKESKYAVDYREMSADERNYFSGMYVDEKSVEGENE"
     gene            1134..1553
                     /locus_tag="ACG8LA_002825"
     CDS             1134..1553
                     /locus_tag="ACG8LA_002825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0205072.1"
                     /translation="MTDSTDKMTIKALADELGITKNTVRNYLVKAGYDLARYKKNGII
                     LLDKELIGVARSIYRSKGGQLTGHLPVNSTGSDFPLEKENEFLRDQLAEKDKHISELT
                     EMIRDQQKLTLLQQQKNDQLLLENQELKNRKWWQFWK"
     gene            1562..1870
                     /locus_tag="ACG8LA_002826"
     CDS             1562..1870
                     /locus_tag="ACG8LA_002826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0205073.1"
                     /translation="MDKIDLREETVNRIEVMYERLADYLNLSDEDNYSEMLERMMDVL
                     NSVINADLAKSSVLTNEFVHKHLAQTTDEAEKEFWLKLMSHIMQLNQISVINSKEKGM
                     "
     gene            1874..2236
                     /locus_tag="ACG8LA_002827"
     CDS             1874..2236
                     /locus_tag="ACG8LA_002827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0205074.1"
                     /translation="MGMTLADIKVQEEKLKKEQAKLRQQKKRLIEKENAAMGKALRKR
                     FGFESFADFERWLSSISDDQQHEKSVGNELRADEKSAPSERNYPNESDGIFGGIPNRK
                     SQMSESGFASMFSDVNSR"
     gene            2458..3864
                     /locus_tag="ACG8LA_002828"
     CDS             2458..3864
                     /locus_tag="ACG8LA_002828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid recombination protein"
                     /protein_id="HFQ0205075.1"
                     /translation="MGFSISFKKGTKNTSISHNNRELTDSQKINDWHKHIDFTKSDEN
                     IYLEQINIREKYEELFGEAVEKYNAKQKRADRKIEDYLAKVRKDKKMEPQREFIVQIG
                     TLDDFRTTRDDGSSTGISEQQAEQNRVIANKILVEYFKEFKERNPSLSVYNAVIHNDE
                     VSPHLHLNIVPVAEGYKRGVQKQPSFNKALQQQGLRADKENGRVIWNNFRNQEVESIE
                     RLMADFGWERELVGTNKIKDIHEYKEIMSEISELRQTAVKERESVSDELRYICRQREE
                     NEREKALVASERAKIEEEKKNMLNVKKEMAVIFQKDMVPLESFKRLPDGSYHLSGNDF
                     VDLYQRATRATNAKRNADNMSEQYLQMLEQNTELNEYVAALEEERHLSGRKQLADLQV
                     ENKKLKEENRSLRQRLERLKNAFQKSITRLSIRFGLAEKDMGLSEELEVLEQEKTLFY
                     RQNVSQHKLERSEDEIEW"
     gene            4313..4432
                     /locus_tag="ACG8LA_002829"
                     /pseudo
     CDS             4313..4432
                     /locus_tag="ACG8LA_002829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303407.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
BASE COUNT         1598 a          652 c         1042 g         1298 t
ORIGIN      
        1 aaaaaaaaag attgcttttt cttccctagt attttatagt tttaattgac tagaaaaaaa
       61 ctaaactaga aaggagagca atctattttt tgttatcggc ttttcagcct tttttgtata
      121 caaaatttgt agattcagta tagcaagatg aaaaagaaaa agcaagattt gattaacgga
      181 acatttcgag aaaaaaagaa aaatttgaaa aaagtggtgg catttagtga taatcgaatt
      241 tctcccaaaa tgcgtgaatt gatgacaggc tgtggttcat atttagaatt tattgcaacg
      301 attgataagg agaaaaagaa attggtccaa gctcactttt gtaaaaatcg tttctgtccg
      361 ttatgtgctt ggcgtaaagc tcgtaaggat tcgatgatgt tgtcgattat gatgcaagct
      421 attgcggaag aaaagcagta tcaatttatt tttatgacgt tgacgacacc gaatgtaaaa
      481 gcggaatgtt tgaacgatga aattgatttg tttaatcatg cattgaaaaa gatgtttatg
      541 cgcaaacggg ttaagacttc gattaaaggc tatgtgcgaa aattggaaat cacgtacaac
      601 aaaaaacgga atgactataa cccgcatttt cacttgattt tggcagtaaa taaatcttat
      661 ttcacggata aagattatta tatcaagcaa tcggaatggt tagatttgtg gcgggaagtg
      721 accggaaaaa cgggaattaa tccggatggt accgacgaaa ttacccagtt ggatattcgc
      781 aaggtcaaag ggttccaaca agaaaaagca gtacaggaag ttgcgaaata ttcggcaaaa
      841 gattttgaac tgaccgaaag tcaggaagtg tttgacacat tctatcatgc aatgaaaggt
      901 cgtcagttga ttacgtttaa cggtgtattc aaagaataca agaaaaaata tgagtcgggt
      961 gaccttgatc gttataagaa aaaagatgag aatgaatatt tttggttttt gactgcttcg
     1021 tggatgagga aagaatcgaa atatgcggtt gattatcgtg agatgagtgc tgatgaaaga
     1081 aattattttt caggaatgta tgtcgatgaa aaatctgttg agggggaaaa tgaatgactg
     1141 attcaacgga taaaatgaca attaaggcgc ttgctgatga actaggaata accaaaaata
     1201 cagtgagaaa ttatctagtc aaagccggat atgatcttgc tcggtacaag aaaaatggaa
     1261 ttatcttgct agacaaagag ttgattggtg ttgctcggtc aatttatcgg tcaaaaggtg
     1321 gtcaattgac tggtcattta ccggtcaata gcacgggcag tgattttcct ttggaaaaag
     1381 agaatgagtt tttgcgtgat caattagctg agaaggacaa acatatttct gaattaacag
     1441 aaatgattcg tgatcaacaa aaattgaccc tgcttcagca acaaaaaaac gatcagttgt
     1501 tactagaaaa tcaagaatta aaaaatcgaa aatggtggca attctggaag tgagatgtga
     1561 catggataaa attgatttga gagaagaaac agtcaataga attgaagtga tgtatgaacg
     1621 gttagctgat tatttgaatc tttcggatga agataattat agtgagatgc ttgaacgaat
     1681 gatggatgtt ctcaactcgg ttatcaatgc tgatctagca aaatcttcag ttttgactaa
     1741 tgaatttgtt cataagcatt tagcgcaaac aactgatgaa gctgaaaaag aattttggtt
     1801 gaaattaatg agtcatatta tgcagttaaa ccaaatttcc gttattaatt ccaaagaaaa
     1861 ggggatgtag tttatgggaa tgactttagc agatattaaa gtgcaagaag aaaaattaaa
     1921 aaaagaacag gcgaaacttc gccaacagaa gaaacgattg attgagaaag aaaatgctgc
     1981 aatgggcaag gctcttcgca agcgttttgg gtttgaatct tttgctgatt ttgagcggtg
     2041 gctatcgtcg atttctgacg atcagcaaca cgaaaaatca gtgggtaatg agttgcgagc
     2101 tgatgaaaaa tcagcaccaa gcgaacggaa ttaccctaac gaatctgacg gaatattcgg
     2161 agggataccg aatagaaaaa gtcagatgag tgagagtgga tttgcgtcaa tgtttagtga
     2221 cgtaaattca cgataagcga atattttgca tgaagcaaaa taaagcgtaa aaggagttga
     2281 gagcgtgaca cgctttcggc tccttttttc gttgtcactt gtgacggcga aaaccctcgg
     2341 agagcgtttg gaattgtgac agtcatgtca caattaggaa aacgttactc tttgacaaag
     2401 agtaacagaa aggtttacac tctttttatt agcgacagcg cgaaggaggg gtttaacttg
     2461 gggtttagta tttcgttcaa aaagggaaca aagaatacaa gcatttctca taataatcgt
     2521 gagttaactg atagccaaaa aatcaatgac tggcataagc atattgattt cacaaaatcg
     2581 gatgaaaata tctatttgga acaaataaat attcgtgaaa aatatgaaga attattcggt
     2641 gaagccgtag aaaaatataa tgcaaagcag aaaagagccg atagaaaaat tgaggactat
     2701 ttagcaaagg ttcgcaagga taaaaaaatg gaaccacagc gagaatttat cgtgcaaatt
     2761 ggtactcttg atgattttcg tactactcgt gatgatggtt cttctactgg catatcggaa
     2821 caacaagcag aacaaaatcg agtgattgcc aacaaaattt tagttgagta tttcaaagaa
     2881 tttaaagaac ggaatcctag tttatccgtc tacaatgctg ttattcataa tgacgaagta
     2941 agtccgcacc tgcatttgaa tattgttcct gttgctgaag ggtataaacg gggtgttcaa
     3001 aagcaaccaa gttttaacaa agccttgcaa cagcagggtt tacgagcaga taaagagaat
     3061 ggtcgagtga tttggaataa ttttaggaat caggaagttg agtcaattga acgtttgatg
     3121 gcagattttg gttgggagcg tgagttagtc ggtactaaca aaatcaaaga tattcatgaa
     3181 tacaaagaaa tcatgagcga aatttccgaa ttgcgtcaaa cggccgtaaa agagcgtgag
     3241 agcgtttctg atgagttgag gtatatttgt aggcaaagag aagaaaacga gcgtgagaag
     3301 gctctggtgg cttctgagag agcgaagatt gaagaagaga agaaaaatat gctgaatgta
     3361 aaaaaagaga tggcggtcat tttccaaaaa gatatggttc ctttagaaag tttcaagagg
     3421 cttcctgatg gttcgtatca tttatctggg aatgattttg ttgatttgta tcaacgagct
     3481 acgagagcaa caaatgccaa gagaaatgct gataacatga gtgagcaata tttacagatg
     3541 cttgagcaaa atacagaatt aaatgagtat gtagctgcat tggaagaaga gcgtcatttg
     3601 tctggtagaa aacaattagc agatttacaa gtggaaaata aaaagcttaa agaagaaaat
     3661 cgctctttac gccagcgttt agagcgatta aaaaacgcat ttcaaaaatc gatcactcgt
     3721 ttgtctatcc gttttgggct tgcagaaaag gatatggggc tttctgagga attagaagta
     3781 ttagagcagg agaaaacctt attttatcgt caaaacgtct cacagcataa attagagcgt
     3841 tctgaagatg agatcgagtg gtagttacga tgtgcagtca acggtaccgg aggcggtttg
     3901 tgccgaggat aaggagttga cggctaaacc actagcctat taagctgaca tttgctaaaa
     3961 aatggccagt ccattttttg gccaacttag cgttagcgaa gtttgggggc gcccttttca
     4021 aagggtgcgg ttttatgttt ttggatattt gcatagctaa agagaagtgc tattattgag
     4081 ttatcaaata aataaactga aaaaagagca aaaaaataaa gtcgagcaac gctggacacg
     4141 ttctcgacct ttacggaaac taatcacact agctccgtaa ctcaaattca ttatacgaat
     4201 aatttcaggt ttcttcaaga ctagagattg ctggttatga attttttaga gttacgtgaa
     4261 ctctggaaaa ttctttccac caatctcttt tttctttgag gaggaactaa atttgagtaa
     4321 aaaaggcacg atcataaatg agtgggaaaa attaacagcc ccctctaaca ggcggttaaa
     4381 tgtaaaaact ttttacaccc ccttaaaaat gcagtggtcg attgatcgaa ttttatgtct
     4441 ttgggttttg gggttttaaa acgaaaaaaa gggggcgatt ttcgccctct tttttgatgt
     4501 tttttcttat cttgatacta taggcaacta tttctgcgaa gaaatcgggg ctatagtatg
     4561 ggtctatccc ttgtggctct aaggaagaac
//
LOCUS       DAZKKZ010000124         4587 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.129, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000124 DAZKKZ010000000
VERSION     DAZKKZ010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4587)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4587)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4587
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.129"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            186..2855
                     /locus_tag="ACG8LA_002830"
     CDS             186..2855
                     /locus_tag="ACG8LA_002830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HFQ0205076.1"
                     /translation="MKKNLKSFFRENGRYAAASFLIPFLILALVYLSIGIYPGSSRSI
                     LASDAFSQFSNFHASFRNVLLGKQSIFYTWNASLGLNYLSLISYYLGGIFTPLVFFFP
                     NQMMPDALYVLTLLKVGCAGLAFWFLARTFKIPRWGHVALSVSYALISFITAHSEIIM
                     WLDAFVYLPLVILGIHRVMDLKRPKLLFISYLLLFLSSFYMGFMIGVFSFLYFIARLL
                     TNWSEYKKTIVPYGITSLLAGGASMIIVLPAVLDLRSNGEALSQITTLKTEATSYLDL
                     IMKNMIGVYDTTKYGSIPFVYAGLLPLVLCLFYFASRKVPLKNKFLYGSLFAILIASF
                     YLVPLNLFWHGMHAPNMFLFRYAYLFSFLVLLLAGKGWEKIEQDDRGLLLGIILVVAA
                     LFAVAWGIKPEGSYTYVTMTSFVLTVVFLGIYAFAVGFYQHKKLSFNHLSILLLLIMS
                     AEALVNTNSMIHGILDDWNYASRSLYTDPYPDLKALVNETKKDSDSFYRLENLDPVSA
                     NDSINYGYSGISLFSSIRNRNSSSYLDKLGFRSRGTNLNIRYNNNTLLMDGFTGIKYN
                     ISKNESTFSKYGFRQAGQSGDYTLYQNVNALPLAFTAPLSVNDVEQPVTDNLTSQTNL
                     INTLSGLNEQYFTFYTPTLKNQLNTTITKTTTGVTYSETADNQPKELTWEVHVPANTQ
                     AYLSLFPTNFAQLESSSATITVNGTSRKTQINISGQYYDLGYYPQETTVTFTASFYGT
                     KEVSFMEPKVVGLDVVAYQAAMNQIKEKGVEMEATGRKASGTVNTAEDSMLVTTIPYD
                     KGWKAKIDGKPVKVSNFKDAFLMIKVPAGKHTVTFSYLPEGFTIGAILFVLCIALFIL
                     YVWYLDRNRPFYGTIDPAIEEKPRNTHRRRRRK"
     gene            complement(2946..3560)
                     /locus_tag="ACG8LA_002831"
     CDS             complement(2946..3560)
                     /locus_tag="ACG8LA_002831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFQ0205077.1"
                     /translation="MINATDEILSVNKVFYTVPAEKMSRVSSDINTITSRIGLTKAMH
                     MVLKYNQEDPPVPKTYEAIDLIIVDEIDRLKLQHLEQLRDIYDRNDLAMVLIGMPGIE
                     KRLSRYPQLYSRIGFAHEFDNLSKDETHHILEYKWADLGIDIKLEDFSDYEAITTIIK
                     ITKGNFRLIHRLFAQIDRILRINQMDKITVEVVEAARDSLVIGI"
     gene            3680..4219
                     /locus_tag="ACG8LA_002832"
     CDS             3680..4219
                     /locus_tag="ACG8LA_002832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0205078.1"
                     /translation="MKKLFSALFILLFGFIGIGTSGNIVKASTMVEQTSEMAKTFSQL
                     TPEEQSYFKSKGFSDKDTFYTQKIEPQDPKTRFSANVLRLTASTKKITNTQGRTEYII
                     TSPNSAMYRISTRLSLGSAKSYTQTVNLANSYGYGGGMYFTFTGKRQYYSVKLAMQVY
                     NTFGVGSVSCTAGGLTIGK"
     gene            4216..4554
                     /locus_tag="ACG8LA_002833"
     CDS             4216..4554
                     /locus_tag="ACG8LA_002833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA];
                     GO_process: GO:0046685 - response to arsenic-containing
                     substance [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arsenic metallochaperone ArsD family protein"
                     /protein_id="HFQ0205079.1"
                     /translation="MIISYYVLNRSDDEGLFVFQSLHEDTMLKEFYNRIKNKQIETNL
                     YFLSDSILPFISNPKILNLLQTKDLKSLPIIVIDEEIVKYGAYLSVEELEKLTNIGMS
                     IQEDNGVHGT"
BASE COUNT         1419 a          790 c          860 g         1518 t
ORIGIN      
        1 atttttaagg gtgggacttt tgattcctac cctttttttg cgtttatttt tgttatacga
       61 acaaattatg aagttattta ttctaaattt tatttttttg tgaaaattag actcttttta
      121 agcagagaaa aacaaggata tgataaactg aatacaactt catagaaatt tggtggaaaa
      181 taaatatgaa aaaaaattta aagtcattct ttagagaaaa cggacgctac gcagcagcta
      241 gtttcctgat tccgtttttg attttagcac ttgtttatct aagtatcggg atctatcctg
      301 gaagcagcag aagtattttg gcaagtgatg ccttttcaca gttttctaat tttcatgcca
      361 gcttccgaaa tgttcttctt ggaaagcaaa gtatttttta tacatggaat gcttctctag
      421 gattgaatta tttatcttta atttcttact atctaggcgg gatcttcacg ccactggtgt
      481 tcttttttcc aaaccagatg atgccagatg cactgtatgt tctgactttg cttaaggtcg
      541 gctgtgccgg attggctttt tggtttcttg cacgtacgtt caagattcct cgctgggggc
      601 atgttgcact tagcgtcagt tacgcattga tctcatttat cactgcacat tcggagatca
      661 tcatgtggct ggatgcattt gtttatcttc cattagtgat tttggggatt catcgtgtta
      721 tggatcttaa acggccgaaa cttttattta tcagttattt actcttgttt ttatccagtt
      781 tttatatggg ttttatgatt ggcgtatttt ctttcttata ttttatcgcc cgtctattga
      841 caaactggtc agaatataaa aaaacgattg ttccttatgg tatcacttct ttactggcag
      901 gcggcgcttc aatgatcatt gtattgccag cagtgctgga tcttcggtca aatggcgagg
      961 cactgagtca gatcactacg ttgaaaacag aagcgacttc ttatctggat ctaatcatga
     1021 aaaatatgat tggtgtttat gacacgacaa aatacggatc gattccgttc gtttacgcag
     1081 gtctgctacc attagtcctc tgtctgtttt attttgccag tcggaaagta ccgttgaaaa
     1141 ataaattttt gtacggcagt cttttcgcca tacttatcgc aagtttctat cttgttccat
     1201 tgaatttgtt ctggcatggt atgcatgcac cgaatatgtt tttattccgt tatgcctatc
     1261 tgttctcttt cttagtgctc ctgcttgcag gaaaaggatg ggaaaagata gaacaagacg
     1321 atcgtgggct gttgttagga atcattttgg tcgtagctgc tctctttgcg gtggcatggg
     1381 gcatcaaacc tgaaggaagc tacacctatg tgacgatgac ttcctttgta ttgacagtgg
     1441 ttttcttagg gatttatgct tttgctgtgg gattttatca gcataaaaaa ctttcattca
     1501 atcatctgag tatattgtta ttattgatca tgtctgctga agcactggtc aatacgaaca
     1561 gtatgatcca tggcattctt gatgattgga attatgcttc ccgcagttta tatactgatc
     1621 cttatcctga cttgaaagct cttgtaaatg aaacaaaaaa agattccgac tcgttttacc
     1681 gcttggaaaa tctggatcca gtatctgcaa acgattcgat caactatggt tacagtggta
     1741 tcagtttgtt ttcttctata agaaatcgta attcttcctc ttacctggat aaattaggtt
     1801 tccgttcaag agggacaaat ttgaatatcc gttataacaa taatactttg ctaatggatg
     1861 ggtttacagg aatcaaatat aacatttcta aaaacgaaag cacgttcagt aaatatggct
     1921 tccgccaagc tggtcaaagt ggcgactata cactgtatca gaatgtcaat gcattgccac
     1981 tagcatttac tgcaccgttg tccgttaatg atgttgagca gccagtgaca gataatttga
     2041 ccagtcagac aaacttgatc aatacattgt ctggtttaaa tgaacagtat tttacattct
     2101 atacacctac tttgaagaat cagttgaata cgacgatcac aaagacaacg actggcgtca
     2161 cttactcaga aacagcagat aaccagccaa aagagctcac ttgggaagtc catgtgcctg
     2221 caaatacaca agcttactta agtttgttcc caaccaattt tgcacaatta gaaagttcta
     2281 gtgcgacgat cactgtcaat ggtacatcgc gaaaaacgca aatcaacatt tctggtcaat
     2341 actatgatct tggctattat cctcaagaga caacagtgac atttactgca agtttttatg
     2401 gaacgaaaga agtaagtttc atggagccta aagtcgttgg tctagatgtt gtagcctatc
     2461 aagccgcaat gaatcagatc aaagaaaaag gtgtcgaaat ggaagccact ggcagaaaag
     2521 cttctgggac tgtaaatacc gctgaagatt ccatgttggt gacaactatt ccttatgaca
     2581 aaggatggaa agctaaaatt gatgggaaac cagtcaaggt cagcaatttc aaagacgcat
     2641 tcttgatgat aaaagttcca gcaggtaaac atactgtcac tttcagttac ttgcctgaag
     2701 gatttacgat aggtgcaatc ctttttgtcc tatgtattgc attgtttatt ctttatgtct
     2761 ggtaccttga ccgcaatcgc cccttttatg gcacgattga tccagcaata gaagaaaaac
     2821 cgcgaaatac acacagaaga agacgaagaa aataaagaaa cgatggaatc tgtgtcactc
     2881 ttctatttaa atggcaaaaa tttcaatctt taaatgacaa aaaccacctg atttttggtg
     2941 gttttttata tacctatgac taaactatct cttgctgctt cgacaacttc tacagtgatc
     3001 ttatccattt gattgattct taaaatccga tcaatctgcg caaataaacg atgaataagc
     3061 ctaaaatttc cttttgtgat cttaatgata gttgtgatag cctcataatc agaaaaatct
     3121 tctagcttga tatcaattcc taaatctgcc catttgtatt ccaaaatatg atgtgtttcg
     3181 tccttactaa ggttatcaaa ttcatgtgca aatcctatgc gagagtaaag ctgcggataa
     3241 cgagacaatc ttttttcaat accaggcata ccgataagaa ccattgccag atcatttcta
     3301 tcgtaaatat ctcttagctg ttctaaatgc tgaagcttta aacgatcaat ttcatcgaca
     3361 ataattaagt caattgcttc ataggtttta ggcacaggag gatcttcttg attgtatttt
     3421 agtaccatat gcattgcttt agtcagacct attctactag ttattgtgtt aatatccgaa
     3481 ctgacacgag acatcttttc agctggtaca gtataaaaaa ctttatttac acttaatatt
     3541 tcatctgttg catttatcaa gaacaagaaa aagtctgaat attcaaaaaa aataacggtg
     3601 tacattttta aaaggagatg tataatcgag atttagaaag cgttttcctc aaaatttaat
     3661 gaattaggaa gtgattacta tgaaaaaatt atttagcgca ctttttattc tgttatttgg
     3721 ctttattggt attgggactt ctggaaatat agttaaagct agcacgatgg ttgaacaaac
     3781 aagtgaaatg gcaaaaactt ttagtcaatt aacaccagaa gaacaaagtt acttcaaatc
     3841 caaaggattt agtgataaag atacttttta cactcaaaag atagagcctc aagatccgaa
     3901 aacacgtttt tctgcaaatg tattgcggtt aaccgcatct actaaaaaaa ttactaatac
     3961 gcaggggcgg acagaatata ttataacaag tcccaattcg gcgatgtatc gtatttctac
     4021 acgcttgagt ttaggtagtg caaaatcata tactcaaaca gtaaatctag ctaattctta
     4081 tggttatggt ggaggaatgt attttacatt tactgggaaa agacaatatt acagtgtaaa
     4141 attagctatg caagtttata atacatttgg tgtagggtca gtctcttgca ctgcgggagg
     4201 attgacaata ggaaaatgat aatttcttac tatgtcttaa atagaagtga tgatgaagga
     4261 ctcttcgttt ttcaatcatt acatgaggat acgatgctaa aagagtttta taatcggatt
     4321 aagaataaac agatagaaac aaatttatat tttttaagtg actctatctt gccttttatt
     4381 agcaacccta aaattcttaa cttgttgcag acaaaagatt tgaaaagttt accgattatt
     4441 gtcattgatg aggaaattgt aaaatatggc gcttatctaa gcgtagaaga attagaaaaa
     4501 ttaactaaca ttggaatgag tattcaggag gataatgggg tacatggaac atagaatgaa
     4561 tatgcacagt tgagaacgga atttgac
//
LOCUS       DAZKKZ010000125         4486 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.130, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000125 DAZKKZ010000000
VERSION     DAZKKZ010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4486)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4486)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4486
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.130"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(28..963)
                     /gene="murB"
                     /locus_tag="ACG8LA_002834"
     CDS             complement(28..963)
                     /gene="murB"
                     /locus_tag="ACG8LA_002834"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008762 - UDP-N-acetylmuramate
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HFQ0205080.1"
                     /translation="MNKEEIVESLATITILFDEPLMNYTFTKTGGPADVLAFPKKQEE
                     VKQIIDYCRIHDIPWMVLGNASNLIVQDGGIRGVVIMLTEMKQIHVKGTMVIAEAGAS
                     LIDTTYAALAESLTGFEFACGIPGSVGGAVYMNAGAYGGEIKDVFAEVDLLLEDGTLK
                     TLTKDEMVFSYRHSKVQELRAIVLEARFSLQTGDYEAIKARMDELTELRQSKQPLEYP
                     SCGSVFKRPVGHYTGQLIQQAGLQGLKWGGAQVSEKHAGFIVNIDHATATDYIELIAH
                     IQEVIKEKFDVSLETEVRIIGEKQAISETSRSLAN"
     gene            complement(1036..1956)
                     /locus_tag="ACG8LA_002835"
     CDS             complement(1036..1956)
                     /locus_tag="ACG8LA_002835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFQ0205081.1"
                     /translation="MKIGVIGVGNIAEKAYLPTYAKKQGTLDFYFATRNKETKERIQK
                     EYGFQHLYETIDELLEEKIEACMIHAATKVHYELAKKCLENGIHVYIDKPLSVHLNEV
                     RELQELADKNQIILMIGFNRRFAPMVEELKRIPDKRLIHLQKNRIAAKETTEFVLYDL
                     FLHLIDTAVYLLDEPILRTKYQIRETKEFLEYAILQLETQNQTAILTMDLASGANIEK
                     YQVTSKNGTYEVNDLTQLVIQDADGKKVKEFGDWTNTLVKRGFEPMVEAFFSQIRLGK
                     SETELLKQKEVVRSHELCEEVLKDHYRHQL"
     gene            2069..2821
                     /locus_tag="ACG8LA_002836"
     CDS             2069..2821
                     /locus_tag="ACG8LA_002836"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HFQ0205082.1"
                     /translation="MKFISWNVNGLRAIVNKNFLEVFHELDADFFCLQETKLQAGQID
                     LDLPGYYQYWNYAERKGYSGTAIFAKKPALNATYGMGIDIHDTEGRLITLEYSDFFLV
                     TCYTPNSQSELKRLDYRLEWEEAFYNYLENLKKQKPVIVCGDLNVAHQKIDLKNWKTN
                     QKNAGFTPEERAALSRLLDNGFIDTFRYFYPTQEGVYSWWNYRFNSRKNNAGWRIDYF
                     LTSKDLEPGLADAKIHTDIMGSDHCPVELDLK"
     gene            3685..4218
                     /locus_tag="ACG8LA_002837"
     CDS             3685..4218
                     /locus_tag="ACG8LA_002837"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HFQ0205083.1"
                     /translation="MNFVAMDFETANHQPYSACSLALVMVKNSQIVDEFYTLIQPETP
                     FFWRNVQIHGIHQEDVRNAPKFPEVWQTIQPYFQKNRLVVAHNAAFDTKVLAGCLDYY
                     HLEQPNYLSLCTVKSSRRLFPEFPNHRLNTVCENLNIQLDHHHDALEDSRACAEILLY
                     QEKKFGTDPLKKLVTIK"
BASE COUNT         1323 a          878 c          795 g         1490 t
ORIGIN      
        1 tttacttatt ttaagttcca ttacttatta attggctaaa cttctgcttg tttctgatat
       61 tgcttgtttt tctccaatga tccgcacttc tgtttctaaa gacacatcaa atttttcttt
      121 gattacttct tggatgtgcg caatcaattc aatataatct gtcgctgtcg catgatcgat
      181 attgacgatg aatccagcat gtttttcaga gacttgtgca ccgccccatt tcaggccttg
      241 caatcctgct tgttggatca gctgacctgt atagtgtcct actgggcgct taaagacact
      301 tccgcatgaa gggtattcta atggctgttt tgattgacgc aattcggtca actcatccat
      361 tcttgctttg attgcttcat aatcccctgt ttgcaaactg aatcgagctt ccaatacgat
      421 agcacgtaat tcttggactt tactgtgacg ataagaaaat accatttcgt cttttgtcaa
      481 agttttcaat gttccatctt caagcaaaag atccacttca gcaaaaacat ctttgatctc
      541 tccgccatac gcacctgcat tcatataaac cgctccaccg acacttcccg ggatgccgca
      601 agcaaattca aatccagtca atgattctgc caaagctgca taagtcgtat caatcagtga
      661 ggcacctgct tccgcaatga ccatcgttcc tttgacatga atctgtttca tttcagtcag
      721 catgatgact acaccgcgaa tcccgccatc ttgaacgatc agattgcttg catttcctaa
      781 taccatccaa ggtatatcat ggattcggca ataatcgatg atttgcttta cttcttcttg
      841 ttttttcggg aatgcaagga catcagctgg tccacctgtt ttcgtaaacg tatagttcat
      901 caatggttca tcaaacaata tagtaatcgt ggctaagctt tcaactattt cttctttatt
      961 cactgaggat tttcctttct tttctcaaac gtcctcatta ttctatcacg cttaatacaa
     1021 tcttgccagt cttgttcaaa gttgatgacg gtagtgatct ttaagcactt cctcacataa
     1081 ttcatgactt cttacaactt ctttttgttt aagcaattct gtttccgatt tacctaaacg
     1141 gatctgagaa aagaaggcct ctaccattgg ctcaaacccg cgtttgacta gcgtgtttgt
     1201 ccagtcgcca aattctttca ctttttttcc atcagcatct tgaatgacaa gctgggtcag
     1261 atcgtttact tcataagtac catttttact tgttacttga tatttttcta tattagcgcc
     1321 acttgctaaa tccatcgtta aaatagccgt ttgattttgt gtttctaatt gtaaaatggc
     1381 atattccaaa aattcctttg tttctcttat ctggtatttt gttctcaaaa tgggttcatc
     1441 taataaatac acagctgtat caataagatg taaaaacaaa tcataaagga cgaactctgt
     1501 cgtttctttt gccgctattc gatttttttg caggtggatc aaccgcttat ctgggatacg
     1561 tttcaattct tctaccatag gagcaaagcg ccggttgaaa ccgatcatca aaattatttg
     1621 gttcttatca gctaattctt gcaattcacg aacttcattt agatggacac tcagtggttt
     1681 gtcaatataa acatggatac cattttctag acattttttg gctaattcat aatgtacttt
     1741 tgttgctgcg tggatcatac atgcttcgat tttttcttct aaaagctcat cgatcgtttc
     1801 atatagatgt tggaacccgt actctttttg aattctttct tttgtttctt tatttcttgt
     1861 tgcaaaataa aaatcaagtg ttccttgttt tttcgcataa gttggtaaat atgctttttc
     1921 tgcgatattc cctacaccga ttacaccaat cttcatctac tttcctcctg gatcatttag
     1981 ttactttcat cttacaccat tttttactaa aatgaggtac aatagtatcg caaaggtaag
     2041 gaaattaatt cgaaggagtg tgcttttatt gaaatttatc tcttggaacg taaacgggct
     2101 tcgtgccatc gtaaataaaa attttttaga agtttttcat gagttagacg ccgatttttt
     2161 ctgtctgcag gaaacgaaac tccaagcagg acaaattgat ttagatcttc caggttatta
     2221 tcaatattgg aattacgcgg aacgaaaagg ctattccggc acagcgattt ttgctaaaaa
     2281 accagcattg aatgccactt acggaatggg tatcgatatc catgatacag aaggccgtct
     2341 gattactttg gaatattccg atttctttct tgtaacctgt tacacgccaa attctcaaag
     2401 cgaattaaaa cgtttagatt accgattaga atgggaagaa gccttttata attatttgga
     2461 aaatctaaaa aaacaaaaac cagtcatcgt gtgtggggat ctaaatgtcg ctcatcaaaa
     2521 gattgatttg aaaaactgga aaacgaatca aaaaaatgct ggattcactc cagaagaaag
     2581 agcggctctt tctcgactgt tggataacgg gtttatcgat acattccgtt atttttatcc
     2641 aacccaggaa ggtgtctact cttggtggaa ctaccgattc aattcaagga aaaacaatgc
     2701 tggttggcgg atcgattact ttttgacgag caaagattta gagccaggac tagctgatgc
     2761 aaagatccat acggacatta tgggcagtga tcattgtcca gtagaattag atttgaaata
     2821 aagaggttgt gaaaaagtcg tttagtttcg agtattaaga aaaattttgt gaaaatggct
     2881 ttccacattt tgcataaatt tggcataata ccgagaaact ggcttttgaa cactgtttat
     2941 cgagagattg tgaaaaagct gtcctgcatc aagtaataag aacagccaaa caaaaatagt
     3001 tcctcatatt tttcgtttgg ttgggcttat taccgcagat acaagctttt gaacaccgtt
     3061 tattaagagg ttgtgaaaaa gctgcactgc atcaagtaat aagaacagcc aaacaaaaat
     3121 agttcctcat atttttcgtt tggttgggct tattaccgca gatgcaagct tttgaacacc
     3181 gtttattaag aggttgtgaa aaagctgcac tgcatcaagt aataagaaca gccaaacaaa
     3241 aatagttcct catatttttc gtttggttgg acttattacc gcagatgcaa gcttttgaac
     3301 accgtttatt gagaagttgt gaaatcagcg tcctgacctg agtattagag aaacaaatgg
     3361 caaaatagtt cctcatattt tgctattttt tgagctaata ccgagggtca gctgattgaa
     3421 caccgtttag tggagaagtt gtgaaaaagt cgcctacttt cgagtcgtaa gaaatttttt
     3481 tgaaaatggt tcctcacaac tttgcataaa tttgacttaa taccgagaag tcatgatccc
     3541 catctaactc caaatcacaa ggaatgagtt caaaaactag cttttctcaa caaatattac
     3601 ataaaaaatt ctatgttttt tgttaaattt atttgctttt ttcaaaagta tgttacagta
     3661 atttcccaag gaggttttac agaaatgaat tttgttgcca tggattttga aactgccaat
     3721 catcagcctt atagtgcttg ttctcttgcg ctagtcatgg taaaaaatag ccagatcgtt
     3781 gatgaattct atacattgat acagcctgag actccttttt tctggcgaaa tgtccaaatt
     3841 cacggaatcc atcaagaaga cgtacgcaat gcgccgaaat tcccagaagt ctggcaaact
     3901 atccaaccat attttcaaaa aaatcgttta gtcgttgcac ataatgctgc ttttgataca
     3961 aaggtcttag cgggatgctt agattattat catcttgaac agcctaatta tctttcttta
     4021 tgtacagtga aaagtagccg tcgcctgttt cctgaatttc caaatcatcg attgaacact
     4081 gtgtgcgaaa atttgaacat ccaattagat catcaccatg atgcattgga agatagtcgt
     4141 gcatgtgcgg aaatcctgct ttatcaagaa aaaaaattcg ggacagatcc attgaaaaaa
     4201 cttgtgacta taaagtaaaa gaatacttat gaaacacaca aagaggtcgt gagcctgccg
     4261 tttcactccg agtcacaagg agcaatttca aaaaatagct tctcatgttt attaaatatt
     4321 gtgactggtg accgaggagc tggcaggaga acaccgttta ttggagaggt tgtgaaaaag
     4381 ctgttctgca tcaagtaata agaacagcca aacaaaaata gcttctcata tttttcattt
     4441 ggttggactt attaccgcag atgcaagctt ttggacaccg tttacc
//
LOCUS       DAZKKZ010000126         4433 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.131, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000126 DAZKKZ010000000
VERSION     DAZKKZ010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4433)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4433)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4433
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.131"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(543..2048)
                     /locus_tag="ACG8LA_002838"
     CDS             complement(543..2048)
                     /locus_tag="ACG8LA_002838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFQ0205084.1"
                     /translation="MIKPKKSEKRELKGPSLTIKWAFASSFFIFVVFTIFAVITYKSS
                     INLIVAKERNNVERTISEVASRLANSDEELTLVNTYRNLTKATNDGDEVVDHTSLVEG
                     NLMKIDSFIAELGQPSMDLYVYDLDENLIFKTHENSRNLIQTTRKVPTIVTLEGKTGF
                     LSIQPIYSKGTREKIGYAQSFYELSSFYDIRNKLLLTLIVLEVVSLILSSILGFFLSS
                     YFLKPLKVLRDTMDTIRKDPQSDIHMPEIDTNDELADLAEIFNEMLDRMRLYIEQQEQ
                     FVEDVSHELRTPVAIIEGHLSLLNRWGKDDPEILEESLSASMQEISRMKSLVQEMLDL
                     SRAEQVDVHYANETTKGKEVTYQVYNNFKILYPDYVITLDDDLTKEVTLQIYRNHFEQ
                     LIIIILDNAVKYSTTRKEVHISISSTLNEFEIAIQDFGEGIPKEDLNKIFNRFYRVDK
                     ARARTKGGNGLGLSIAKQLVENYKGRILAESVVGQGTIFRIFIPIAKAEDK"
     gene            complement(2045..2731)
                     /locus_tag="ACG8LA_002839"
     CDS             complement(2045..2731)
                     /locus_tag="ACG8LA_002839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010763438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFQ0205085.1"
                     /translation="MSNILIIEDEKNLARFVELELKHEGYNAEVHYNGRTGLDAALNN
                     EWDAILLDLMLPELNGLEVCRRVRQVKNTPIIMMTARDSVIDRVSGLDHGADDYIVKP
                     FAIEELLARLRALLRRIDIEGDKNVAKQTTITYRDLTIEKENRVVRRGNEVIELTKRE
                     YELLLTLMENVNVVLARDVLLNKVWGYETEVETNVVDVYIRYLRNKIDVPGEESYIQT
                     VRGTGYVMRS"
     gene            complement(2924..4345)
                     /gene="gndA"
                     /locus_tag="ACG8LA_002840"
     CDS             complement(2924..4345)
                     /gene="gndA"
                     /locus_tag="ACG8LA_002840"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004616 - phosphogluconate dehydrogenase
                     (decarboxylating) activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HFQ0205086.1"
                     /translation="MSKQQIGVVGMAVMGKNLALNIESRGYSVALFNRTGAKTTAVVE
                     EHPDKNFKATYTIEEFVESIEKPRRILLMVKAGPATDATIQELLPHLDKGDILIDGGN
                     TFFKDTMRRNEELANSGINFIGTGVSGGEEGALKGPSIMPGGQKEAYALVAPILEQIS
                     AKAEDGAPCVTYIGPNGAGHYVKMVHNGIEYGDMQLIAESYDLMKNILNLSVEEMADI
                     FKEWNQGELDSYLIEITADILTRKDDEGTGKPVVDVILDAAGNKGTGKWTSQSALDLG
                     VPLPLITESVFARYISAYKEERVQASKILSRTNDFEFTGDKKELVEKIREALYFSKIM
                     SYAQGFAQLRVASKEFDWDLPFGEIAKIWRAGCIIRARFLQKITDAYDKNPEIENLLL
                     DDYFVEITKKYQQSVRDVVALAVQAGVPVPTFSSAIAYFDSYRAERLPANIIQAQRDY
                     FGAHTYERVDKEGIFHYSWYHEE"
BASE COUNT         1239 a          919 c          729 g         1546 t
ORIGIN      
        1 tctttttgtt ttaacaactc tttaatctta tcagattcag aagagaatgt caacaacttc
       61 tttgtttatt ttttctaaac gtctttgcca ctcattagca gcgacttgat tatcatacca
      121 tctttattgt tatttgtcaa taactttttc gaagtttttt tcgataaaat caagctttat
      181 tagctatctc atccaaacga cttcgttatt ataacatgac atcaaaagtg cgtcaacact
      241 attttttata atttttagtg acaccttaaa ggaatcattt agaacaaata ataatatagc
      301 aatctcttta taaaattgca atagaaaatt ccctattttt atttattatt tttaaacacg
      361 aatattacag cattttattg ttttttcgtt catctaaaag atacttacat ttaattaacg
      421 gatgttattc tatttaattg ttcgctagtt tttttataat gacatccctg aatttctcac
      481 ttgcttgtat tttgtacctt attctttgtt ggatatataa aaaaacaagt aaagcacatg
      541 ctttacttgt cttctgcctt tgcgatagga ataaagattc taaaaattgt cccttgccct
      601 actacacttt ctgctaagat acgtccttta tagttttcaa ccagttgttt agcgatagac
      661 aaccccagac catttccacc cttcgttcta gctcttgctt tatccactcg ataaaaacga
      721 ttgaagatct tattaaggtc ttctttgggt attccttcgc caaagtcctg aatcgcgatc
      781 tcaaattcat tcagagtgga agaaatagag atatggactt cttttcgtgt agttgaatac
      841 tttactgcgt tatccaatat gataatgatt aattgttcaa agtgattacg ataaatttgc
      901 agggtcactt cttttgtcaa atcatcatct aaagtgatca catagtctgg atataatatc
      961 ttgaaattat tataaacttg ataggtgact tcttttcctt tagttgtttc attcgcataa
     1021 tgaacatcta cttgttctgc tcttgataag tctagcatct cttgaactaa gcttttcata
     1081 cggctgattt cttgcatgct ggcgcttaat gattcttcta atatctcagg atcatctttc
     1141 ccccaacgat ttagcagact aagatgccct tcaataattg caacaggtgt ccttaactca
     1201 tgagatacgt cttccacgaa ttgctcttgt tgttcaatat acaaacgcat acggtcaagc
     1261 atctcattga atatttcagc taaatctgcc aattcatcat ttgtgtcgat ttcaggcatg
     1321 tggatatctg attgcggatc tttacgtata gtatccattg tatctctgag taccttgagt
     1381 ggttttaaga aataagaaga taaaaagaaa cctaaaatac tacttaagat caaagaaaca
     1441 acttctaaaa caataagagt caataatagc ttatttcgaa tatcatagaa agaagataat
     1501 tcatagaagc tttgcgcata gccgatcttt tctcttgtac ctttagaata tataggctgg
     1561 atagataaaa agccagtttt tccttctagt gtaacgatcg ttggaacttt acgtgtagtc
     1621 tgaatcaggt ttcgactgtt ttcatgggtt ttaaaaatca agttctcgtc caaatcataa
     1681 acataaagat ccattgatgg ctgccctagc tcagctataa aggaatcgat cttcattaag
     1741 tttccttcga ccagtgaagt atgatctacg acctcatctc cgtcatttgt cgctttcgtc
     1801 agattacgat acgtatttac taatgtcagt tcttcatccg agttagccaa acgagaagct
     1861 acttctgaaa tcgtacgctc tacattgttt ctttcttttg ccacaatcag attgatagat
     1921 gatttatagg taatgacagc gaaaattgta aacacaacga atatgaagaa agaactcgca
     1981 aaggcccact tgattgtcaa ggagggccct ttcagttctc ttttttccga ttttttcggc
     2041 tttatcacga gcgcatcaca taacctgttc cgcgtacagt ttggatatag ctttcctccc
     2101 cgggaacgtc aattttgttg cgaagataac gaatatatac gtccactacg tttgtttcaa
     2161 cttctgtttc gtatccccac actttattta gtaaaacgtc acgtgctaat accacgttca
     2221 cgttttccat taaagtaagc agcaactcgt attctctttt tgttagttca attacttcat
     2281 ttccgcgacg tacgacacgg ttttcttttt cgatagtcaa atcgcgataa gtaatagtag
     2341 tttgtttagc cacattttta tcgccttcaa tatcgattcg acgcaacaat gcacgaagac
     2401 gtgctaataa ttcttcgata gcaaatggtt tgacgatgta gtcatctgct ccgtggtcaa
     2461 gtccagatac acgatcgatc acagaatctc ttgcagtcat cataatgatt ggtgtatttt
     2521 tgacttggcg tacacgtctg cagacttcta aaccgttcaa ttctgggagc atcagatcca
     2581 acaatatggc atcccactca ttatttaatg ccgcatctaa accagttcgg ccgttgtagt
     2641 ggacttctgc gttataccct tcatgcttca actctagctc gacaaatcgt gccaagttct
     2701 tttcatcttc aatgattaga atattgctca tttattattt tatcctttct attctactgg
     2761 ctttttaaaa actctatcat tataccgata atatgcttaa aaatctatag tcattttatc
     2821 atggatagca attttaaaaa agagctgaag tctactcata acaatcgact tcagctcttt
     2881 cgtcctcttt ttattttctc atttcctaac agccgaaaga ctattattct tcatggtacc
     2941 atgagtaatg gaagattcct tctttgtcga cacgctcata ggtatgtgcg ccaaagtaat
     3001 cgcgttgggc ttggattata tttgcaggca gacgttctgc tctgtatgaa tcgaagtaag
     3061 cgatggctga tgagaaagtc ggtacaggta cgccagcttg gacagccaag gcaacgacgt
     3121 ctctgactga ttgctgatat tttttcgtga tttcaacgaa gtaatcatct agcaataaat
     3181 tttcgatctc aggatttttg tcataggcat ccgtaatttt ttgcaagaat cgagctcgga
     3241 tgatacatcc agcgcgccag atttttgcga tttcaccaaa tggcaagtcc caatcaaatt
     3301 cttttgaagc gacacgtaat tgagcaaatc cttgggcata actcatgatt ttactgaaat
     3361 acaacgcttc tcggattttt tcgaccaatt cttttttgtc tcccgtgaac tcaaaatcgt
     3421 tcgtacgaga caaaatcttg cttgcttgta cgcgttcttc tttataagca gaaatatagc
     3481 gggcaaatac agattcagtg atcaatggaa gtggcacacc taagtcaagc gcgctttggc
     3541 ttgtccattt acctgttcct ttattcccag ctgcatcaag gatcacatct actactggtt
     3601 tacctgttcc ttcatcgtct ttacgtgtca gaatgtcagc agtgatttct atcaaatagc
     3661 tgtctaattc gccttgattc cattctttaa agatatcagc catttcttct actgaaaggt
     3721 ttaaaatatt cttcattaag tcataagatt cagcaatcag ttgcatatct ccatactcaa
     3781 taccgttgtg taccattttc acataatgtc cggctccatt tgggccaata tatgtgacac
     3841 atggtgctcc gtcttctgct tttgcagaaa tttgctctaa gattggtgca actagcgcat
     3901 aggcttcttt ttgtccacca ggcatgattg aaggtccttt taaagctcct tcttcaccac
     3961 cggaaacgcc tgtaccgata aagttgatgc cagagttggc taactcttca ttacgacgca
     4021 tcgtatcttt aaagaatgta tttcctccgt caatcaaaat atcgccttta tcaaggtgag
     4081 gaagtaactc ttggattgtt gcatctgttg ccggtcctgc tttgaccatt agcaagatcc
     4141 gacgtggttt ctcgatagat tctacaaatt cttcgattgt atatgttgct ttgaaatttt
     4201 tatctgggtg ttcttctact acagcggttg ttttagcccc tgtacgattg aataaagcca
     4261 ctgaatagcc gcggctttct atgttcaagg ctagattttt acccataacg gccataccga
     4321 caacgccgat ttgttgtttt gacatatgaa ctcctcctac atacgggatt tctccctaat
     4381 ctcttacatt atagcttaac acggctacat tgcaaactaa agaacaacat att
//
LOCUS       DAZKKZ010000127         4403 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.132, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000127 DAZKKZ010000000
VERSION     DAZKKZ010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4403)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4403)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4403
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.132"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..1015
                     /locus_tag="ACG8LA_002841"
     CDS             <1..1015
                     /locus_tag="ACG8LA_002841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="YSIRK-targeted surface antigen transcriptional
                     regulator"
                     /protein_id="HFQ0205087.1"
                     /translation="DFNEMFLLYMFKTRYYLFGPFRANNIDKDFFKLKMNNLNVAMAD
                     RERLYNSLQNLTLYSLGDIRDILILVHYFFTGKIEDLFHEPLIEYTGNLSKTIEQIKI
                     DNLLSQNYDPEIYLFLYENKILEYVKNGDIRNLENMVFNLSNGIIPSVSGDTIRSEKN
                     YSIIVFEKLAQTSITLGMDIIEAYQSRDALIQENELAVSLPEVLKVRDSGIVYYTKEI
                     GKTKIEHLSPLISSVVQFIGLNIYKRITVKEIANYFSVSETKLRESFKNEMHITIYNY
                     ISKRKISTAKIMLKSNHTISEVSLGLGFSDSSHFSRVFKKYAGVSPKQYQLGLVDNFN
                     NIS"
     gene            1112..1465
                     /locus_tag="ACG8LA_002842"
     CDS             1112..1465
                     /locus_tag="ACG8LA_002842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0205088.1"
                     /translation="MSCFVESERLSNGNNSVLNEYDKVVINKVKSLCEEARESISHIN
                     GSNFKQTLFNLIKLDAKISSYLFFLIHDEFMDYQKLDQLIERESWEDYYVGLTFSEKL
                     NNYKLIDYKYLSESN"
     gene            2082..>4403
                     /gene="esp"
                     /locus_tag="ACG8LA_002843"
     CDS             2082..>4403
                     /gene="esp"
                     /locus_tag="ACG8LA_002843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="repetitive surface protein Esp"
                     /protein_id="HFQ0205089.1"
                     /translation="MVSKNNKRVFLEKTKKRVLKYSIKKLSVGVASVLVGVGLVLGTT
                     ELVQAQDEISPSTPLETAISSVQVGDKVASGNTFQENPGYTKNYNFSDLQFSPQELTG
                     DTLKGNTIGFEVYGKHNIAASTKNWEIRLQLDERLAKYVEKIQVDPKKGIGSSRRTFV
                     RINDSLGRPTNIWKVNYIRASDGLFAGAETTDTQTAPNGVITFEKSLDEIFKEIGIDN
                     LKTDRLMYRIYLVSHQDDDKIVPGIDSTGYFLTDSDDFYNSLDVSENNPDQFKHGSVS
                     AKYEEPNTQTKDGSGSTGANGAIILDHKLTKNYNFSYSASAKGTPWYANYKIDERLVP
                     YVAGIQMHMVQADKVTYDVSFESGKKVADLAIERRKDHENYGVGSITDNDLTKLIDFA
                     NASPRPVVIRYVLQLTKPLDEILEDMKATAQVEENKPFGEDFIFDSWLSDTNKKLIQN
                     TYGTGYYYLQDIDGDGNPDDKEESGDTNPYIGKPELEEVYDVDTTVKGKVFIHELAGT
                     GHKAQLVDKEGTVLAEKTIAPNEKDGAPISDTVEFEFTGVDSSKLIAKDELKIQIVSP
                     GFDKPEEGSTVIKESPKAVDKQTVVVGFKPDAKESIRNNKNLPEDAEYSWKTEPDTSN
                     VTDSTKGIVTVKIGNRTFDVDVEFAVKASQAMENDATYVPITTTPETTVQSGKPTFDK
                     PDVPLAKDAFSILDVYNKDFGNASVDANTGIVTFTPAKGVGESEPITGTIPIKIVYQD
                     GSVGTTDLAVTVSKDIYENPGENIPAGYHKVTFT"
BASE COUNT         1614 a          602 c          819 g         1368 t
ORIGIN      
        1 tgattttaat gagatgtttc ttctatacat gtttaaaacc agatattact tatttggtcc
       61 atttagagca aataatattg ataaagattt ttttaaacta aaaatgaaca atttgaatgt
      121 tgcaatggct gatagagaac gactctataa ttcattgcaa aatttgactt tgtattcttt
      181 aggagacatt cgagatattc tgattttagt tcattatttt tttactggaa aaatagaaga
      241 tctattccat gaaccgttaa ttgaatatac aggaaatcta agtaaaacta tcgagcaaat
      301 caaaatagat aatctgttat cacaaaatta cgatccagaa atatatctgt ttctttatga
      361 aaataaaata ctggaatatg ttaaaaatgg agatattcga aatttagaaa acatggtttt
      421 taatctgagt aatggaataa ttccaagtgt tagtggagat acgattcggt ctgaaaaaaa
      481 ttattctatc attgtttttg aaaagttagc acaaacgtct ataacattag gaatggatat
      541 aatagaagcg tatcaaagta gagatgcttt gatacaagaa aacgaattag ctgtatcgtt
      601 acctgaggtc ttaaaagtga gggattctgg gattgtttat tatactaagg aaatcggaaa
      661 aactaagata gagcatcttt ctcccttaat ttcttctgtc gttcaattca tcggcttaaa
      721 tatctataaa agaattactg taaaggaaat agctaattat ttttctgtaa gtgaaactaa
      781 attaagagaa agctttaaga atgaaatgca tattacgatt tataattata tctctaagcg
      841 aaaaatttct acggctaaaa taatgttgaa atcaaaccat actatcagtg aagtttcttt
      901 aggtttagga ttttcagatt cttcacactt ttcgagagta ttcaaaaagt acgcaggtgt
      961 atctcctaag caatatcaat taggtttagt ggataatttc aacaacatta gctgagaggt
     1021 tttattttat tatgagacta tatcatttac gtagtttgga ggagttgagg aaattggatt
     1081 ttaacaaaaa attttttggg aaatttctga tttgagttgt ttcgtagaat ctgagcgtct
     1141 aagtaatggt aataatagtg tgttaaatga atatgacaaa gtagtaatta ataaagtaaa
     1201 aagtttatgt gaagaagcta gagaatctat cagtcatatt aatggtagca attttaagca
     1261 aacattattt aatctgatta agctagatgc taaaatatca agttatttat tctttttaat
     1321 acatgatgaa tttatggatt atcaaaaatt ggatcagtta attgaaagag aaagctggga
     1381 agattattac gtgggtctaa ctttttcaga aaagttaaac aactacaagt taatagatta
     1441 taagtatttg agtgaaagca attaattatt catgtagagt actagacact ttaaatatgg
     1501 acaattcaat tataaagaaa aagaatcaat aatttaatga ggctgtgaca aatgtcattt
     1561 tttgtttcgc taaaaacgag tgaaaaaatg ttgataactc caatcattcg tttaagattc
     1621 taggaatcat tcaggaatgc tgtgaaaccg atactttata attataaaga aggtgatttc
     1681 aaattccgaa gaaggaattt gaagtcacct ttttacttat gtcacagtct cattcagtaa
     1741 tgcgggataa ggctccttat tccgctattt gaatactctg aagtttaatc taagaaagag
     1801 taatattttg aaaacatgct tcatcgcata gaaatgaact taatttcaga aagaatacat
     1861 acatatcttt ttatatgttt tcagctgctg aatggttaaa aagcacaaat atccgaaaaa
     1921 aacatgaaga aatgtacttt ttttgttgta atgtgcatga aattctttaa gtaaactagt
     1981 taacataagt ttagtaagat tcctattctg tgaataatac gtatcagatt tatcttttat
     2041 tcttactaag aaaataacta ttaagggagt tgatttgaat aatggttagc aagaataata
     2101 agagagtatt tctagaaaaa acaaagaaac gagtattgaa gtacagtatc aaaaaattaa
     2161 gtgttggggt tgcatctgtt ttggttggtg ttggtcttgt cttgggaaca actgaactag
     2221 ttcaagcaca agatgaaatt tctccaagca ccccacttga aacagcgata agctccgtac
     2281 aagtaggtga caaagtagct tcggggaata cttttcagga gaatcctggt tatacgaaaa
     2341 attataactt ttcggattta caatttagtc ctcaagaact aactggagac acactaaaag
     2401 gcaatacaat tggatttgaa gtttacggaa aacataatat tgcagcatca actaaaaact
     2461 gggaaatccg tcttcaatta gatgaacgat tagctaaata tgtagaaaaa attcaggtcg
     2521 atccaaagaa aggaattgga tcttctagac ggacctttgt aagaattaat gattcgctgg
     2581 gtagacctac aaatatttgg aaggtcaatt atattcgtgc aagtgatgga ttatttgctg
     2641 gggctgaaac aactgataca caaactgctc ctaatggggt aattacgttt gaaaagagct
     2701 tagatgaaat ttttaaagag ataggcatag acaatctcaa gaccgatcgt ttaatgtatc
     2761 gaatctactt ggtaagtcat caagacgatg ataaaattgt accaggtatt gatagtacgg
     2821 gctacttttt aacagattca gatgatttct ataatagctt agatgtatct gaaaataatc
     2881 ctgaccagtt taaacatgga tcagtaagtg caaaatatga ggaacctaat actcaaacaa
     2941 aagatggttc aggatccaca ggtgctaatg gagctataat cttagatcat aagttaacga
     3001 aaaattataa tttctcatat tcagcttccg caaagggcac gccttggtat gctaattaca
     3061 aaattgatga acgattagtt ccatatgtag cgggtataca gatgcacatg gttcaggctg
     3121 acaaagtaac atatgatgtt tcttttgaat cagggaaaaa agtggctgat ttagcaattg
     3181 aacggcgcaa agatcatgaa aattatggtg taggttcaat tactgataat gatcttacca
     3241 aacttattga ttttgctaat gcaagtccac gtccagtcgt tattcgatat gttttacaat
     3301 tgactaagcc attagatgaa atcttagaag atatgaaagc aacagcacaa gttgaagaaa
     3361 ataaaccatt tggtgaagat ttcatctttg attcttggtt gtcggatacg aataaaaaat
     3421 taatccagaa cacttatgga acaggttatt attatttgca agatattgat ggtgatggaa
     3481 accctgacga taaagaagag agcggagaca cgaatccata tatcgggaaa cctgaattag
     3541 aagaagtata tgatgttgac acaacagtta aggggaaagt attcatccac gagttagcgg
     3601 gaacaggtca caaagcccaa cttgttgata aagaaggtac tgtattagca gaaaaaacta
     3661 tcgctccaaa tgaaaaagat ggggctccaa tttcagatac tgtagaattt gaatttacgg
     3721 gtgtagattc aagtaaatta atcgcgaaag atgaattaaa aatccaaatc gtttctccag
     3781 gttttgataa accagaagaa ggttcaaccg ttattaagga atcaccaaaa gcggttgata
     3841 aacaaaccgt ggtagttgga tttaaaccag atgctaaaga atcaattcgg aataataaaa
     3901 acttacctga agatgcagag tattcatgga aaacagagcc tgatacttct aacgttactg
     3961 atagtacgaa aggtattgta actgttaaga tcggaaatcg aactttcgac gtggatgtag
     4021 agtttgctgt aaaagcttct caagctatgg aaaatgatgc aacatacgta cctataacaa
     4081 caactccaga aacgacagtt caaagtggaa aacctacatt tgataaacca gatgttcctt
     4141 tagctaaaga tgccttttca attttagatg tctataataa ggacttcggt aatgcaagtg
     4201 ttgatgcaaa tactggtatt gttacattca ctccagctaa aggtgtagga gaatcggagc
     4261 cgattactgg aacaattcct attaaaattg tttaccaaga tggttctgta ggcacgaccg
     4321 atttagcagt aactgtaagt aaagatattt atgaaaatcc aggagaaaac attcctgcag
     4381 gctaccacaa agtgaccttc acc
//
LOCUS       DAZKKZ010000128         4070 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.134, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000128 DAZKKZ010000000
VERSION     DAZKKZ010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4070)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4070)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4070
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.134"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..792)
                     /locus_tag="ACG8LA_002844"
     CDS             complement(<1..792)
                     /locus_tag="ACG8LA_002844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015543625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein RepR"
                     /protein_id="HFQ0205090.1"
                     /translation="MNIPFVVETVLHDGLLKYKFKNSKIRSITTKPGKSKGAIFAYRS
                     KSSMIGGRGVVLTSEEAIQENQDTFTHWTPNVYRYGTYADENRSYTKGHSENNLRQIN
                     TFFIDFDIHTAKETISASDILTTAIDLGFMPTMIIKSDKGYQAYFVLETPVYVTSKSE
                     FKSVKAAKIISQNIREYFGKSLPVDLTCNHFGIARIPRTDNVEFFDPNYRYSFKEWQD
                     WSFKQTDNKGFTRSSLTVLSGTEGKKQVDEPWFNLLLHETKFSGEK"
     gene            complement(835..1134)
                     /locus_tag="ACG8LA_002845"
     CDS             complement(835..1134)
                     /locus_tag="ACG8LA_002845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0205091.1"
                     /translation="MNHDECKTYIKNSLLEIRKLANIYTLETFKKELEKRNIYLETKS
                     DKYFSSEGEDYIYKLIENNKIIYSISGKKLTYKGKKSFSKHAILKQLNEKANQVN"
     gene            complement(1500..1784)
                     /locus_tag="ACG8LA_002846"
     CDS             complement(1500..1784)
                     /locus_tag="ACG8LA_002846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFQ0205092.1"
                     /translation="MELAFRESLKKMRGTKSKEKFSQELEMSRSNYSRIESGKSDPTI
                     KTLEQIAKLTNSTLVVDLIPNEPTEPEPETESEQVTLDLEMEEEKSNDFV"
     gene            complement(2303..2788)
                     /gene="vanZ-A"
                     /locus_tag="ACG8LA_002847"
     CDS             complement(2303..2788)
                     /gene="vanZ-A"
                     /locus_tag="ACG8LA_002847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance protein VanZ-A"
                     /protein_id="HFQ0205093.1"
                     /translation="MGKILSRGLLALYLVTLIWLVLFKLQYNILSVFNYHQRSLNLTP
                     FTATGNFREMIDNVIIFIPFGLLLNVNFKEIGFLPKFAFVLVLSLTFEIIQFIFAIGA
                     TDITDVITNTVGGFLGLKLYGLSNKHMNQKKLDRVIIFVGILLLVLLLVYRTHLRINY
                     V"
     gene            complement(2941..3852)
                     /locus_tag="ACG8LA_002848"
     CDS             complement(2941..3852)
                     /locus_tag="ACG8LA_002848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala carboxypeptidase VanY-A"
                     /protein_id="HFQ0205094.1"
                     /translation="MKKLFFLLLLLFLIYLGYDYVNEALFSQEKVEFQNYDQNPKEHL
                     ENSGTSENTQEKTITEEQVYQGNLLLINSKYPVRQESVKSDIVNLSKHDELINGYGLL
                     DSNIYMSKEIAQKFSEMVNDAVKGGVSHFIINSGYRDFDEQSVLYQEMGAEYALPAGY
                     SEHNSGLSLDVGSSLTKMERAPEGKWIEENAWKYGFILRYPEDKTELTGIQYEPWHIR
                     YVGLPHSAIMKEKNFVLEEYMDYLKEEKTISVSVNGEKYEIFYYPVTKNTTIHVPTNL
                     RYEISGNNIDGVIVTVFPGSTHTNSRR"
BASE COUNT         1226 a          742 c          591 g         1511 t
ORIGIN      
        1 cttttctcct gaaaatttcg tttcgtgcaa taagagatta aaccagggtt catctacttg
       61 ttttttgcct tctgtaccgc ttaaaaccgt tagacttgaa cgagtaaagc ccttattatc
      121 tgtttgtttg aaagaccaat cttgccattc tttgaaagaa taacggtaat taggatcaaa
      181 aaattctaca ttgtccgttc ttggtatgcg agcaatacca aaatgattac acgttagatc
      241 aactggcaaa gactttccaa aatattctcg gatattttgc gaaattattt tggctgcttt
      301 gacagattta aattctgatt ttgaagtcac atagactggc gtttctaaaa caaaatatgc
      361 ttgataacct ttatcagatt tgataatcat agtaggcata aaacctaaat caatagcggt
      421 tgttaaaata tcgcttgctg aaatagtttc ttttgccgtg tgaatatcaa aatcaataaa
      481 gaaggtattg atttgtctta aattgttttc agaatgtcct ttcgtgtatg aacggttttc
      541 gtctgcatac gttccataac gataaacgtt gggtgtccaa tgtgtaaatg tatcttgatt
      601 ttcttgaatc gcttcctcgg aagtcagaac aacaccacga ccgccaatca tgcttgattt
      661 tgagcgatac gcaaaaatag cccctttgct tttacctggc ttggtagtga ttgagcgaat
      721 tttactattt ttaaatttgt actttaacaa gccgtcatga agcacagttt ctacaacaaa
      781 agggatattc attcagctgt tctcctttcc tataaatcct ataaaatagg ttgtttaatt
      841 aacttggttt gctttttcat tcaactgttt caatattgca tgttttgaaa aagatttttt
      901 tcctttataa gtcaattttt ttccactaat cgaataaatt attttgttat tttctattaa
      961 cttatatata taatcttccc cctccgaaga aaaatactta tctgattttg tttctaagta
     1021 gatatttctc ttttctaact ctttcttaaa cgtttctagt gtatagatat ttgctaattt
     1081 tcttatctcc aataaactat tttttatata agttttacat tcatcatgat tcatacaaac
     1141 tccaccttct ataaatgaat acaaaaaaag caatcaaacg atttccgatt gattgcttaa
     1201 caattcttaa attcagtagc ttagatactt gaaaactctc tgatttccct atataatgat
     1261 agtacggtta tataccgtct tcaaacaaag ttaattaaat aacttcttac gagggaagag
     1321 ttcatctgac taactgataa gcgttggttt ggcaatctta tcgggctatg catttataaa
     1381 atgtcgtcaa acattttata aatgtgtcat ggctcttttt tcgtttctat tcagttcgtt
     1441 gtttcgttat atctagtata ccgcttttaa aaaaaataag caacgatttc gtgcattatt
     1501 cacacgaagt cattgctttt ttcttcttcc atttctaaat ccaatgttac ttgttctgat
     1561 tctgtttctg gttctggttc tgttggctca tttgggatta aatccactac tagcgttgag
     1621 ttagttaact ttgcaatttg ttctagtgtt tttatggttg gatctgattt tcctgattct
     1681 attcgtgaat aatttgatct actcatttct aattcttggg agaatttttc ttttgatttg
     1741 gtacctctca tcttttttaa gctttctcta aatgctagtt ccaagtttct cccccctctt
     1801 tttgtgtaat aaaattcacg ctttatttaa attatagctt ttaatatctt aataaacaag
     1861 tgattaatca cttgtgattt gtgattattc caaaagtagg taatttcacc aacctttttc
     1921 aaaagttttt atcgacgatt attggactgg atcgtgtttc ctaaagcgat tctaagcgca
     1981 tgtttaattt taaagtgggt aattctcttt aaaacgtcct acaaagattc aaaaaaagca
     2041 tggctgctag tgggggtacc gtcaggaaaa tgcggattta caacgttaag gaaatttatt
     2101 aaagagacca attcctcagc actaaaattg ataattgggc tttctttgtt actatagtgt
     2161 taggtaagct ttttacttta tcaccggttt tcccctcact tcacacctac gggcgagttt
     2221 ccccacatcc cgttttccat ctaatccaat tcattcaata tctttatgtg tatgaaagat
     2281 cagattgctt gatttagaca tcttacacgt aatttattct taaatgggta cggtaaacga
     2341 gcaataatac gagcaaaagt atacctacaa aaataataac tctgtctaat tttttttgat
     2401 tcatatgctt attgcttaaa ccatataatt tcagtccaag aaagcctcca acagtatttg
     2461 taattacatc tgttatgtct gtcgctccaa tagcgaagat aaattgaatt atttcaaaag
     2521 taagacttaa aaccagtaca aaagcaaact taggtaaaaa tccgatttct ttaaaattga
     2581 cattcaaaag caagccaaat ggaataaaga ttataacatt atctatcatc tctctgaaat
     2641 tcccagtagc agtaaatgga gtcaagttaa gacttctttg atgataatta aatactgata
     2701 aaatattgta ttgtaatttg aataacacta accagattag tgtcactaaa tataaagcta
     2761 gcaatcctct agataatatt tttcccaata taatttcctc taattctttt gtttaagttg
     2821 tatcattagt atagcaatgt cctagttaac gtgggtttta aattaaaaag ctaacgttac
     2881 cccaaaagtg ctagtacaat aatgctgttc attaatttcg ttggtttcat tccgccatcc
     2941 ttacctcctt gaattagtat gtgttgatcc gggaaacact gtcacaatta caccgtctat
     3001 attgtttcct gatatctcat aacgaagatt agtcggcaca tgaatggtgg tatttttagt
     3061 aacaggataa taaaagatct catatttttc cccatttaca ctaacagaaa tggttttttc
     3121 ttcttttagg taatccatat attcctcgag aacgaaattc ttttctttca taatcgcact
     3181 atgtggtaaa ccaacatagc gaatatgcca tggttcatat tgaattcctg ttaactctgt
     3241 tttgtcctct ggataacgta aaatgaaccc gtatttccaa gcattttctt ctatccactt
     3301 tccttcaggg gctcgttcca ttttcgtcaa gcttgatcct acatctagtg ataaacctga
     3361 attatgctca ctataacctg ctggtaaggc atactcagcc cccatttctt ggtaaagcac
     3421 actttgctca tcaaagtctc gatagccact attaataata aaatgactaa cgccaccctt
     3481 tacagcatca ttgaccatct ctgaaaattt ttgtgctatt tcttttgaca tataaatatt
     3541 actatcaagc aacccgtatc catttattaa ttcgtcatgt ttagataaat tcacgatatc
     3601 tgacttcaca ctttcttggc gaacaggata tttactattg attaatagca gatttccttg
     3661 ataaacctgt tcttctgtaa ttgttttctc ttgggtattt tcagaagtcc cactattttc
     3721 taaatgttct ttgggatttt gatcataatt ttgaaattcg actttttcct gagaaaacag
     3781 tgcttcatta acgtagtcat aacctaagta tattaagaat aacaataaca ataaaaaaaa
     3841 caacttcttc attttcagtc tcctccttaa ctatatagtt ggaagtatga aatatttcta
     3901 gaatcttccc cttaaacggc acaatctcgt ttgagattgt gccgttttgc cccgtaaatt
     3961 acagtcaatt atttcgccct actggattta ctattatcac caatgtagat gaattttcat
     4021 aagtgatacc catgctgaat ttaacgaggc tgaactgcct gttgacaatg
//
LOCUS       DAZKKZ010000129         4068 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.135, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000129 DAZKKZ010000000
VERSION     DAZKKZ010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4068)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4068)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4068
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.135"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            87..1436
                     /locus_tag="ACG8LA_002849"
     CDS             87..1436
                     /locus_tag="ACG8LA_002849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015171 - amino acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFQ0205095.1"
                     /translation="MNEEQELQRGLKNRHVQLISIGGAIGTGLFLGSGKSIQLAGPSI
                     LLAYLITGCICFFIMRALGELLLSNTNNHSFLDFVAEYLGKKAAFITGWTYWFCWVSI
                     AMADLTAIGMYVRYWAPGVPQWLPELIALGLLLCLNMVAVSLFGELEFWFALIKVVAI
                     IAFILVGAYMILTHYTTDIGTASITNLWSHGGFFPTGAKGFILAFQMVTFAFAGIELV
                     GLVAGETENPEKVLPEAINNIPIRIILFYLGSLFVIMAIYPWNSLNPDNSPFVEVFSE
                     IGITIAASLINLVVLSAAASACNSAIYSTGRMLRSLAQEGSAPKKFKKLTTHHVPGNA
                     LTFSTIVIFISVILNYVMPSEVFTLVSSIATTCFLFIWSMLVYTHMKYRKSILGKKAH
                     SFKMPLYPFSNYLVFLYMAFVCVVLFLGKDTRIALLLTPVWFLLLLLIYHMKYERKK"
     gene            complement(1564..2154)
                     /locus_tag="ACG8LA_002850"
     CDS             complement(1564..2154)
                     /locus_tag="ACG8LA_002850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0071805 - potassium ion transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TMEM175 family protein"
                     /protein_id="HFQ0205096.1"
                     /translation="MTKSRLEAFTDGVVAIVLRVLVLEIKIPNTSSFHSLWVIRNTLL
                     AYTISFIFVAVIWVNHHRIFQMAERINYRVVWSNIFLLFWLTLCPSVTSWVGRNPEAF
                     WPEMAYVLVYTMWSFSFGILMRQIMKANKPDSHVVRVLSKDRRSLISMMINLCLIAGV
                     FFVPLIGLFGRFFVSGIWIFSYKKADAYYQRLFPGK"
     gene            2301..3653
                     /gene="brnQ"
                     /locus_tag="ACG8LA_002851"
     CDS             2301..3653
                     /gene="brnQ"
                     /locus_tag="ACG8LA_002851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015658 - branched-chain amino acid
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015803 - branched-chain amino acid
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HFQ0205097.1"
                     /translation="MTKKLSFKDYLFIGSMLFGLFFGAGNLIFPVHLGQEAGAATFWA
                     NLGFLVTGIGLPFLGVIAIGVSKSSGVYELAKRINQTYAMVFTILLYLVIGPFFALPR
                     LATTSFEIGLAPFIDPSRQTLYLAIFSIVFFVLAWWFSRKPTKILDYVGKFLNPAFLV
                     LLGALLLLAFLNPLGSVNQAPIQPNYQEHAFFTGFTQGYNTLDALAALAFGIIIVTTI
                     QNMGVTKPAEIAKDTIKSGAISIILMGIIYTLLAYLGAMSLGSFALSENGGITLAQIA
                     DHYLGTYGSILLAFIVILACLKTGIGLITAFAETFTDLFPQRNYAFFVALASILPCLA
                     ANVGLTNIIQFSLPVLMFIYPLAMTLILLVLVGPLFKQRTAVYRMTTYFTLIASIFDG
                     LNACPETIKQTPIVQNLLYVAESYLPFFKLGMGWIVPAVIGFVIGLIWSFAKKEEVAD
                     "
BASE COUNT         1173 a          744 c          790 g         1361 t
ORIGIN      
        1 gaaaattttg gaatcttagt tgtgtttttc agaaaactct cttaatatgg aagtaattaa
       61 acttttttag ttaggatgat ttaaaaatga atgaagagca agaactgcag cgtggactga
      121 aaaatagaca tgtccaactg atttctattg gcggagcgat tggaacgggg ttgtttttag
      181 gttccggaaa gtctatccag ctagctggcc cttcgatatt gctcgcctat cttattactg
      241 gatgcatctg ttttttcatt atgcgtgcgt taggcgaact tctgttatca aacaccaata
      301 accattcttt tctggatttt gttgcagaat atcttggcaa aaaagcggct ttcatcactg
      361 gctggacgta ttggttctgc tgggtatcga ttgcaatggc cgatttaaca gccatcggaa
      421 tgtatgtacg ctactgggcg cctggtgttc ctcagtggct tcctgaactg attgcattag
      481 gtcttcttct ttgcttgaat atggtggctg tctcattgtt tggtgagtta gagttttggt
      541 ttgcattgat caaagttgta gcgatcattg cctttatcct cgtaggagct tatatgatcc
      601 tcacccacta tacgacagat attggcacag ccagtatcac gaatctatgg tctcatggcg
      661 gattctttcc aactggtgca aaaggattta tcttagcttt ccaaatggta acctttgctt
      721 ttgctgggat agaattagtt ggattagtcg ctggagaaac agaaaatcct gaaaaagtgt
      781 tgccggaagc tatcaataat attcctatca ggatcatctt attttactta ggatctcttt
      841 ttgtcattat ggcaatctat ccatggaaca gcttgaatcc agataacagt ccatttgtag
      901 aagtattttc ggaaattggg atcacgattg ctgcttcctt gatcaattta gtcgtattaa
      961 gtgcagcagc ttctgcctgc aacagtgcaa tatatagtac aggacgtatg cttcgttctt
     1021 tagcgcaaga aggcagtgcc cctaaaaaat tcaaaaagtt aacaacacat catgtgccag
     1081 ggaatgcttt gacattttct actatcgtca ttttcatttc tgttatcttg aattacgtga
     1141 tgcctagtga agtattcaca ctagtaagca gtattgccac tacttgtttc ttgtttatct
     1201 ggagtatgct tgtctacacg cacatgaaat atcgtaaaag tatcctcggc aaaaaagctc
     1261 attcatttaa aatgccgttg tacccattta gtaattatct ggtatttctt tacatggcct
     1321 ttgtgtgtgt cgtcttgttc ctaggaaaag atacgagaat cgctttatta ctaacacctg
     1381 tgtggttctt gcttctatta ctaatctatc atatgaaata tgaacgtaag aagtaagaaa
     1441 gtagttgtga cagaagtggt cagcttcgag aaataagaag gaatttacga aaattgcttc
     1501 ttaaattttt gtgaaatttc ggcttatttc ttggagataa aagcttctgt cccagcctct
     1561 tttctatttc cccggaaaca accgctgata ataggcatct gcttttttat aggaaaaaat
     1621 ccaaatacca gatacaaaaa aacgtccgaa taacccgatc aacggtacaa aaaagacacc
     1681 ggcaatcaag cataagttaa tcatcatgga gataagactt cgacggtcct ttgacaaaac
     1741 tctcacgaca tgggaatctg gtttatttgc tttcatgatt tgcctcatca agataccaaa
     1801 agaaaaactc cacatcgtgt atactaagac ataagccatc tcaggccaaa aagcttcagg
     1861 gttacgcccg acccaactag taacagaagg acataaagtc agccaaaaga gcaaaaagat
     1921 attcgaccag accactcggt aattaattcg ttctgccatc tgaaatatac gatgatggtt
     1981 cacccagatc accgcaacaa atataaagct gatggtataa gctaataatg tatttcggat
     2041 gacccataaa gaatgaaagc tagatgtatt agggatcttg atctctaata caagaactct
     2101 caaaacaatg gctaccactc catcagtaaa tgcttctaat ctcgactttg tcacgatgat
     2161 tcctcctcag atgattcagc gcttttattt tatcacttac gttattaaat aaccatcgtt
     2221 ttatataggg aattttctga aaattgttgc atatttttcg aaattttgtt acttttaaaa
     2281 aaaccgtaaa ggagttatgt atgacaaaaa aattatcatt taaagactat ctttttatag
     2341 gctccatgct tttcggtcta ttttttggtg ctggaaatct tatctttccc gttcatttgg
     2401 gtcaagaagc aggcgctgct accttttggg cgaatctagg tttcttggtt accggtatcg
     2461 gtcttccctt cttaggggtg attgccattg gtgtatcgaa aagctcaggt gtatatgaat
     2521 tagcaaaacg gataaatcaa acatatgcga tggtttttac catcttgctt tacttagtta
     2581 tcggaccgtt ttttgcttta cctcgccttg caaccacatc tttcgagatt ggtttagcac
     2641 catttatcga tcctagcaga cagacgctat atctagcaat tttcagtatt gtattttttg
     2701 tgctggcttg gtggttttca agaaaaccga caaagatatt agattatgtt ggaaagttcc
     2761 tgaatcctgc atttttggtt ttattaggtg ctttgcttct ccttgctttt ttgaatccac
     2821 taggttctgt aaatcaagcg cctattcagc caaattatca agagcatgct tttttcacag
     2881 ggtttactca aggatataac acattagatg cgcttgctgc tttagcattt gggatcatca
     2941 ttgtcacaac aatccaaaac atgggtgtaa caaaacctgc tgaaatcgct aaagacacga
     3001 tcaaatctgg tgcgatcagc attatattga tgggaatcat ttatactttg ctcgcttatt
     3061 taggtgctat gagcttaggt agctttgctc taagtgaaaa tggcgggatc acgctggctc
     3121 agattgctga tcattattta ggtacttatg gcagtatctt attagcattt atcgttatat
     3181 tagcttgctt gaagaccggt attggtttga ttacagcttt tgcagaaaca ttcacagatt
     3241 tgtttccgca aagaaattac gcattctttg ttgcacttgc tagtatcctt ccttgtttag
     3301 cggcaaacgt aggcttgacg aatatcattc aattttcgtt gcctgttttg atgttcatct
     3361 atccattagc aatgacactg attttactag tgttagttgg tcctttgttt aagcagcgta
     3421 cggctgttta tcgaatgact acttatttta cattgattgc ttcgattttt gatgggttga
     3481 acgcttgccc agaaactatc aaacaaacac ctattgttca aaatctttta tatgttgcgg
     3541 aaagctactt gccgtttttc aaattgggga tggggtggat cgtaccagca gttatcggtt
     3601 ttgttatcgg actgatttgg agtttcgcta agaaagaaga agtagcagat tgataaaaga
     3661 ggttgtgaaa gagacgttca gccttgagca ataaaaagta attttgaaaa atggcttctc
     3721 acatttttgc ataaatttga cttaataccg agaaactgac ttttgaacac cgtttattga
     3781 gaggtcgtga aaaagccgct tagtttcaag tattaagaaa tattttgtga aaatggcttc
     3841 tcacattttt gcataaattt gacttaatac cgagaaactg gcttttgaac accgtttatt
     3901 gagcgtctat aaactgacct gagtattaga gaaacaaaac ggcaaagtag ctccatatac
     3961 tttgccgttt tgttttgaac taataccgaa gagaagctga tcaaacaaca tttcttttat
     4021 aatatagatt ttagacatat atatgatata aaaatagttt tcgcaaaa
//
LOCUS       DAZKKZ010000130         3898 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.137, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000130 DAZKKZ010000000
VERSION     DAZKKZ010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3898)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3898)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3898
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.137"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            289..1104
                     /locus_tag="ACG8LA_002852"
     CDS             289..1104
                     /locus_tag="ACG8LA_002852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0205098.1"
                     /translation="MVKIAGLSKGGKTVSQLYKQNYRDWRQFRKNIKDSYFILPTELE
                     KYLPNNKAINLYLYYCFKAKNEGGDSWHSVNTIAESLGVTTKTINTWNKTLVDLGMIA
                     RIDDNHLSKSTILLPLSSYYKLALDSSLKDVTESTVHEIDGNLVAVYHLFEWRKNEAD
                     ENYNVPYNTLCCVFKRKTQKDTIYKFILVQDEKISNFELSTPSSKIYDDAYRFECQDL
                     EALLSANNLNNIEHENFVVNTRFNLVSEKDSDLLDLLIELTKNLDKKENITVL"
     gene            1230..1487
                     /locus_tag="ACG8LA_002853"
     CDS             1230..1487
                     /locus_tag="ACG8LA_002853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0205099.1"
                     /translation="MANLYIENKGDLNAIITLIVVMVKSIGNITIGMLFIILAAVLIF
                     MIVIWFLNERSKDNQHRRDMEIKSIESIDYLSIITLKKPRS"
     gene            complement(1739..2311)
                     /locus_tag="ACG8LA_002854"
     CDS             complement(1739..2311)
                     /locus_tag="ACG8LA_002854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFQ0205100.1"
                     /translation="MTKYGYARVSTASQSTKEQIQQLLENGVEKKNIFSEKFTGTKRD
                     RPKFNQLLAGLKPGDEIVVTKLDRFARNTREALEIIEPLLDDNVTIKVLNLGTIENTS
                     MGRMVTRTLLSVAEMERDMIVERTQEGKMFARKNNPNFREGRPKATITPKKRHAYELL
                     TSGKSYKEVEAITGFSRSTLFRIKKKIEES"
     gene            complement(2327..2932)
                     /gene="fic"
                     /locus_tag="ACG8LA_002855"
     CDS             complement(2327..2932)
                     /gene="fic"
                     /locus_tag="ACG8LA_002855"
                     /EC_number="2.7.7.108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042803 - protein homodimerization
                     activity [Evidence IEA];
                     GO_function: GO:0070733 - AMPylase activity [Evidence
                     IEA];
                     GO_process: GO:0018117 - protein adenylylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="protein adenylyltransferase Fic"
                     /protein_id="HFQ0205101.1"
                     /translation="MILENKLGLTNQVELAKVEEKLSKQKAKELYDCGKINEIEVGTF
                     KGLSEIHEFLFSDIYDFAGKIRSVNIAKGNFRFAPVMYLEHSLQHIDQMPQTSFEEII
                     KKYVEMNIAHPFREGNGRSTRIWLDLILKEELQKVVDWNLIDKADYLSAMERSPINDL
                     EIRYLISNALTDKIDDRELYMKGIDVSYFYEGYSEYTIDDL"
     gene            complement(3333..>3898)
                     /locus_tag="ACG8LA_002856"
     CDS             complement(3333..>3898)
                     /locus_tag="ACG8LA_002856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016181348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HFQ0205102.1"
                     /translation="YFKSEKDTSSLTLTLEEGVEPDKVTSKVINQLKEKGSLKHLGEY
                     EVLDTAMLTKGIGQILSTITYFITAVAGISLFIAGVGVMNMMYISVSERTKEIGIRRA
                     LGATRKSIMLQFLLEGLILTLSGGLIGYLLGMALAYSVGSLIKVNVSLDLFTILLAVG
                     VSSVIGLVFSVMPASEAAKKDLIDILR"
BASE COUNT         1295 a          715 c          582 g         1306 t
ORIGIN      
        1 aaaaataaga aattcaaaaa agaaaaaact ttccttaaaa acaaaaaata ggagtattca
       61 gtttcttaat agttttgtaa tagttgtatg tagaagtttt cttaatagtt tttgtaataa
      121 tttattaatc gtagtttata taacttattt gtaagtgact agagaattaa ataaaaaata
      181 attactatct agtacgaaat taattacata ggataatata ttaaggtgct ggactacaag
      241 taaaaaatac tgtatgatca tgacagattc aagaaaggag caataagatt ggttaagata
      301 gcaggacttt ctaaaggtgg aaaaaccgtt tcacaacttt ataaacaaaa ctacagagac
      361 tggagacagt tcagaaaaaa cattaaggat tcttacttta ttctaccaac agaacttgaa
      421 aaatatttac cgaataacaa agctattaat ttatatctgt attactgttt taaggcaaag
      481 aatgaaggcg gggattcctg gcattcggtc aataccatag cagagtctct aggagtgaca
      541 actaaaacta taaacacctg gaataaaacc ttagttgatt taggtatgat tgcacgtata
      601 gacgataacc atctcagtaa atcgacaatt ttacttcctc tctctagtta ctataaatta
      661 gcccttgata gttctttaaa ggatgttacc gagagcactg tccatgaaat tgatggcaac
      721 ttggttgcag tttatcattt gtttgaatgg agaaaaaatg aggctgatga aaattataac
      781 gttccttata acacactctg ttgtgttttt aaaagaaaaa cacaaaaaga tactatctat
      841 aaatttatct tggtccaaga tgagaaaata agtaatttcg aattaagcac tccttctagt
      901 aagatttatg acgatgcata tagatttgaa tgtcaagatc tagaagccct cctttccgca
      961 aataatctaa acaatataga acatgaaaac tttgttgtaa acactagatt taatttagtt
     1021 tctgaaaagg actcagattt gttagatttg ctgatagagc ttactaaaaa tctagataag
     1081 aaagaaaaca ttactgtact ataactagca tcggtccatc attaagtttg gactattaga
     1141 acacttgcta ttacagaaaa aggtatgcta gccacgctta ctatttattg gtatcaaaca
     1201 agtatcttaa tttgaaagga agatgattta tggctaattt atatatagag aacaaaggag
     1261 acttgaatgc cattattact ttaatcgtag ttatggtaaa atcaataggt aatatcacaa
     1321 taggaatgct gtttattata ttagcagcag tgctgatttt tatgatagtt atttggttct
     1381 taaatgaaag atctaaagac aatcaacacc gtagggatat ggagataaaa tcaatagagt
     1441 caatagatta tttatcgata ataacactaa aaaagccacg ttcctaaacg tgacttacgc
     1501 tgaacgatat gtgttgtttg gtagacgaac aaatcgttca ttataaatat atgatggtat
     1561 cctaatatag taagcgtggc tagcatacct ttaattactt taccttttac agttaccata
     1621 cacatttttt gagcagaaat caagtaaata aaaaaatatt atatttcaca acatgctaat
     1681 agactcatat ctagaacgca ttaagtattt acctgtctgg ttcgctgaga cttctttttt
     1741 aactttcttc aattttcttc tttattctaa aaagcgtact gcgactgaaa ccggttatag
     1801 cttcaacttc cttatacgat ttacctgaag taagcagttc atatgcgtgc ctcttcttcg
     1861 gtgtgattgt tgctttcgga cgtccttctc tgaaattagg attattcttt cttgcaaaca
     1921 tttttccttc ttgggtacgt tccacaatca tatcacgttc catttctgct acactcaaca
     1981 acgtccgtgt caccattcgc cccatggacg tattttcaat cgttcctaga ttcaaaacct
     2041 tgatcgttac gttatcatcg agtaaaggtt caatgatctc taatgcttct ctcgtgttac
     2101 gagcaaatcg atcaagcttc gtaacaacta tttcatctcc aggcttcaga ccagccaaca
     2161 gctgattgaa ttttggccga tcccgttttg tacccgtaaa tttttctgaa aaaatattct
     2221 tcttctctac gccgttctca agcaactgtt gaatttgttc ttttgtactt tgagaagcgg
     2281 ttgagacacg tgcatatcca tatttcgtca tttggtccac ctacttttac aaatcatcta
     2341 tcgtatactc agaataccct tcatagaaat agctgacatc gattcctttc atatataact
     2401 cgcgatcgtc aattttatca gtcagagcat tggaaattag atagcgtatt tccaaatcgt
     2461 ttatgggact tcgctccatt gcagaaagat agtctgcttt atcgattaag ttccaatcta
     2521 caactttttg caattcttcc tttaaaatga gatccagcca aattctagta cttcggccat
     2581 ttccttctcg aaatgggtga gcgatattca tctccacata tttcttgata atctcttcaa
     2641 aagaagtttg tggcatctga tcaatatgct gtaacgaatg ttctaaatac ataactggtg
     2701 caaatcgaaa atttcctttt gcaatattga ccgatcggat ttttccggca aaatcgtaaa
     2761 tatccgaaaa tagaaattca tgaatttcag ataaaccttt aaatgtacca acttcgattt
     2821 catttatttt tccacaatcg tacaattctt tcgctttttg tttactgagt ttttcttcaa
     2881 ccttagccaa ctcaacttga ttggttaatc ccaatttatt ctctaaaatc atgcgaaatc
     2941 tccttaactt tatgacataa gtttatgaaa cactctcaac cccattatat cgcgattttg
     3001 tttatgtgtc aaaaactatt aagtttctga cccccgatag atttttcaag tgtctctatt
     3061 ttgcacagtc tagttgacct ttgatacacc tctatattta tagagaatct aaaacatcaa
     3121 catggcatac tcaaaattct aaatattagg gataaagaat tctcctatac aatcaaaaat
     3181 ttcctttatt tcgaactccg gtcacctaac tctattgatc tcttacaagc caaagaatat
     3241 ctctatacta caaagaaaca atagggtgcc tggttggtct ctttgtgttt tattttagaa
     3301 tctagaacgt aaatattctt gtcattctga ttttatctaa gaatatcaat taaatctttt
     3361 tttgcagcct ctgaagcggg cattacagaa aagaccagtc caataaccga agatacccca
     3421 accgctagta aaatagtaaa tagatcaagt gacacgttta cctttatcaa agaaccaaca
     3481 ctataagcaa gagccattcc taataaatag ccaattaacc ctcctgaaag agttaaaatc
     3541 aaaccttcta aaaggaactg cagcataatc gattttcgag tagctcctag ggctcttctt
     3601 ataccgatct cttttgttcg ttcagataca gatatataca tcatgttcat tacacctacc
     3661 cctgcgataa ataaagatat acctgctaca gctgttataa aataagtgat cgtactgagg
     3721 atttgaccaa ttcctttcgt taacatagcc gtatctaaca cttcatattc ccccaaatgt
     3781 ttcaaactac ctttttcttt caattggttt atcactttag aggtcacctt gtcaggttca
     3841 actccttcct ctaaagttaa cgttagagac gatgtatcct tttcagactt aaaataat
//
LOCUS       DAZKKZ010000131         3883 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.138, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000131 DAZKKZ010000000
VERSION     DAZKKZ010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3883)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3883)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3883
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.138"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..1040
                     /gene="vanS"
                     /locus_tag="ACG8LA_002857"
     CDS             <1..1040
                     /gene="vanS"
                     /locus_tag="ACG8LA_002857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="vancomycin resistance histidine kinase VanS"
                     /protein_id="HFQ0205103.1"
                     /translation="MIRGKLGDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVA
                     IVISILILCRVMLSKFAKYFDEINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTL
                     EKREQDAKLAEQRKNDVVMYLAHDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITL
                     DKAYRLEQLIDEFFEITRYNLQTITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIH
                     APEDLTVSGDPDKLARVFNNILKNAAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPK
                     DKLAAIFEKFYRLDNARSSDTGGAGLGLAIAKEIIVQHGGQIYAESNDNYTTFRVELP
                     AMPDLVDKRRS"
     gene            1255..2223
                     /locus_tag="ACG8LA_002858"
     CDS             1255..2223
                     /locus_tag="ACG8LA_002858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="HFQ0205104.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKS
                     APFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAY
                     SPDSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKA
                     VIERLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQ
                     RMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQ
                     FLLKLQRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
     gene            2216..3247
                     /gene="vanA"
                     /locus_tag="ACG8LA_002859"
     CDS             2216..3247
                     /gene="vanA"
                     /locus_tag="ACG8LA_002859"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008716 - D-alanine-D-alanine ligase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanA"
                     /protein_id="HFQ0205105.1"
                     /translation="MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGIT
                     KSGVWKMCEKPCAEWENDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKS
                     GEDGSIQGLFELSGIPFVGCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPV
                     AATFTYPVFVKPARSGSSFGVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCA
                     VLGNSAALVVGEVDQIRLQYGIFRIHQEVEPEKGSENAVITVPADLSAEERGRIQETA
                     KKIYKALGCRGLARVDMFLQDNGRIVLNEVNTLPGFTSYSRYPRMMAAAGIALPELID
                     RLIVLALKG"
     gene            3253..3861
                     /locus_tag="ACG8LA_002860"
     CDS             3253..3861
                     /locus_tag="ACG8LA_002860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="HFQ0205106.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTY
                     ELAESLLKAKELAATQGYGLLLWDGYRPKRAVNCFMQWAAQPENNLTKESYYPNIDRT
                     EMISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEA
                     QNRRRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
BASE COUNT         1170 a          754 c          931 g         1028 t
ORIGIN      
        1 caatgatccg agggaaactt ggggattgga tcttaagtat tttggaaaac aaatatgact
       61 taaatcacct ggacgcgatg aaattatatc aatattccat acggaacaat atagatatct
      121 ttatttatgt ggcgattgtc attagtattc ttattctatg tcgcgtcatg ctttcaaaat
      181 tcgcaaaata ctttgacgag ataaataccg gcattgatgt acttattcag aacgaagata
      241 aacaaattga gctttctgcg gaaatggatg ttatggaaca aaagctcaac acattaaaac
      301 ggactctgga aaagcgagag caggatgcaa agctggccga acaaagaaaa aatgacgttg
      361 ttatgtactt ggcgcacgat attaaaacgc cccttacatc cattatcggt tatttgagcc
      421 tgcttgacga ggctccagac atgccggtag atcaaaaggc aaagtatgtg catatcacgt
      481 tggacaaagc gtatcgactc gaacagctaa tcgacgagtt ttttgagatt acacggtata
      541 acctacaaac gataacgcta acaaaaacgc acatagacct atactatatg ctggtgcaga
      601 tgaccgatga attttatcct cagctttccg cacatggaaa acaggcggtt attcacgccc
      661 ccgaggatct gaccgtgtcc ggcgaccctg ataaactcgc gagagtcttt aacaacattt
      721 tgaaaaacgc cgctgcatac agtgaggata acagcatcat tgacattacc gcgggcctct
      781 ccggggatgt ggtgtcaatc gaattcaaga acactggaag catcccaaaa gataagctag
      841 ctgccatatt tgaaaagttc tataggctgg acaatgctcg ttcttccgat acgggtggcg
      901 cgggacttgg attggcgatt gcaaaagaaa ttattgttca gcatggaggg cagatttacg
      961 cggaaagcaa tgataactat acgacgttta gggtagagct tccagcgatg ccagacttgg
     1021 ttgataaaag gaggtcctaa gagatgtata taatttttta ggaaaatctc aaggttatct
     1081 ttactttttc ttaggaaatt aacaatttaa tattaagaaa cggctcgttc ttacacggta
     1141 gacttaatac cgtaagaacg agccgttttc gttcttcaga gaaagatttg acaagattac
     1201 cattggcatc cccgttttat ttggtgcctt tcacagaaag ggttggtctt aattatgaat
     1261 aacatcggca ttactgttta tggatgtgag caggatgagg cagatgcatt ccatgctctt
     1321 tcgcctcgct ttggcgttat ggcaacgata attaacgcca acgtgtcgga atccaacgcc
     1381 aaatccgcgc ctttcaatca atgtatcagt gtgggacata aatcagagat ttccgcctct
     1441 attcttcttg cgctgaagag agccggtgtg aaatatattt ctacccgaag catcggctgc
     1501 aatcatatag atacaactgc tgctaagaga atgggcatca ctgtcgacaa tgtggcgtac
     1561 tcgccggata gcgttgccga ttatactatg atgctaattc ttatggcagt acgcaacgta
     1621 aaatcgattg tgcgctctgt ggaaaaacat gatttcaggt tggacagcga ccgtggcaag
     1681 gtactcagcg acatgacagt tggtgtggtg ggaacgggcc agataggcaa agcggttatt
     1741 gagcggctgc gaggatttgg atgtaaagtg ttggcttata gtcgcagccg aagtatagag
     1801 gtaaactatg taccgtttga tgagttgctg caaaatagcg atatcgttac gcttcatgtg
     1861 ccgctcaata cggatacgca ctatattatc agccacgaac aaatacagag aatgaagcaa
     1921 ggagcatttc ttatcaatac tgggcgcggt ccacttgtag atacctatga gttggttaaa
     1981 gcattagaaa acgggaaact gggcggtgcc gcattggatg tattggaagg agaggaagag
     2041 tttttctact ctgattgcac ccaaaaacca attgataatc aatttttact taaacttcaa
     2101 agaatgccta acgtgataat cacaccgcat acggcctatt ataccgagca agcgttgcgt
     2161 gataccgttg aaaaaaccat taaaaactgt ttggattttg aaaggagaca ggagcatgaa
     2221 tagaataaaa gttgcaatac tgtttggggg ttgctcagag gagcatgacg tatcggtaaa
     2281 atctgcaata gagatagccg ctaacattaa taaagaaaaa tacgagccgt tatacattgg
     2341 aattacgaaa tctggtgtat ggaaaatgtg cgaaaaacct tgcgcggaat gggaaaacga
     2401 caattgctat tcagctgtac tctcgccgga taaaaaaatg cacggattac ttgttaaaaa
     2461 gaaccatgaa tatgaaatca accatgttga tgtagcattt tcagctttgc atggcaagtc
     2521 aggtgaagat ggatccatac aaggtctgtt tgaattgtcc ggtatccctt ttgtaggctg
     2581 cgatattcaa agctcagcaa tttgtatgga caaatcgttg acatacatcg ttgcgaaaaa
     2641 tgctgggata gctactcccg ccttttgggt tattaataaa gatgataggc cggtggcagc
     2701 tacgtttacc tatcctgttt ttgttaagcc ggcgcgttca ggctcatcct tcggtgtgaa
     2761 aaaagtcaat agcgcggacg aattggacta cgcaattgaa tcggcaagac aatatgacag
     2821 caaaatctta attgagcagg ctgtttcggg ctgtgaggtc ggttgtgcgg tattgggaaa
     2881 cagtgccgcg ttagttgttg gcgaggtgga ccaaatcagg ctgcagtacg gaatctttcg
     2941 tattcatcag gaagtcgagc cggaaaaagg ctctgaaaac gcagttataa ccgttcccgc
     3001 agacctttca gcagaggagc gaggacggat acaggaaacg gcaaaaaaaa tatataaagc
     3061 gctcggctgt agaggtctag cccgtgtgga tatgttttta caagataacg gccgcattgt
     3121 actgaacgaa gtcaatactc tgcccggttt cacgtcatac agtcgttatc cccgtatgat
     3181 ggccgctgca ggtattgcac ttcccgaact gattgaccgc ttgatcgtat tagcgttaaa
     3241 ggggtgataa gcatggaaat aggatttact tttttagatg aaatagtaca cggtgttcgt
     3301 tgggacgcta aatatgccac ttgggataat ttcaccggaa aaccggttga cggttatgaa
     3361 gtaaatcgca ttgtagggac atacgagttg gctgaatcgc ttttgaaggc aaaagaactg
     3421 gctgctaccc aagggtacgg attgcttcta tgggacggtt accgtcctaa gcgtgctgta
     3481 aactgtttta tgcaatgggc tgcacagccg gaaaataacc tgacaaagga aagttattat
     3541 cccaatattg accgaactga gatgatttca aaaggatacg tggcttcaaa atcaagccat
     3601 agccgcggca gtgccattga tcttacgctt tatcgattag acacgggtga gcttgtacca
     3661 atggggagcc gatttgattt tatggatgaa cgctctcatc atgcggcaaa tggaatatca
     3721 tgcaatgaag cgcaaaatcg cagacgtttg cgctccatca tggaaaacag tgggtttgaa
     3781 gcatatagcc tcgaatggtg gcactatgta ttaagagacg aaccataccc caatagctat
     3841 tttgatttcc ccgttaaata aacttttaac cgttgcacgg aca
//
LOCUS       DAZKKZ010000132         3655 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.139, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000132 DAZKKZ010000000
VERSION     DAZKKZ010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3655)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3655)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3655
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.139"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..868
                     /locus_tag="ACG8LA_002861"
     CDS             <1..868
                     /locus_tag="ACG8LA_002861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="glycosyltransferase family 1 protein"
                     /protein_id="HFQ0205107.1"
                     /translation="IEVNKLLKKESFSIVHNQVYFGGGINLWLAKKNGIRQRIAHSHA
                     TEDGKSQNIVMNVLRKFLTKLLLQNATDYLAVSQEAGESLFQNHPFEIVHNGIDLELY
                     SKNSEAKVNKRKELDISMSTFVVGNIGRLEKQKNQSYLLEIFLEILKMNSDSYLILVG
                     EGSLRNKLKAKAVELDIEKRVKFLGERNDIPELLSVMDVFVMPSLYEGLPMVGLEAQA
                     AKLKLVLADTISKDTKLTNNVDFVSLDETPQEWAKKVIKEPYANKITQELKSYDVSYT
                     TEQMESIYSRDH"
     gene            901..1863
                     /locus_tag="ACG8LA_002862"
     CDS             901..1863
                     /locus_tag="ACG8LA_002862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-1,6-N-acetylglucosaminyltransferase"
                     /protein_id="HFQ0205108.1"
                     /translation="MKICYLILAYNDIGNLKRLVNRLNENAVFIIHIDKKTDIEPFIE
                     AFKSYDNVEFLCNKNRVKIYWGGFSIVQAEINLVKRALQNEKYLKYVLLSGADYPIKD
                     NEYIYNYFKKNSSVEFIRGIDLDQIKHKEFYYKHIDVYQKHDYPRINRNNTTAFKIFR
                     AIINRCLRMIKLPPKIRHHKFDLYHGSQWWALSKECLTELIQMYEQNQQDYLNFKIGM
                     FAPDEKFFHTLFFNSSFKNKNVIGGPDLPLELKNIEETTLQTSKLANIHIIDPSMNKW
                     FDERDIDQIKESEKLFVRKVKSDYSDKLLNRIDKEILKVGNIDE"
     gene            1856..3283
                     /locus_tag="ACG8LA_002863"
     CDS             1856..3283
                     /locus_tag="ACG8LA_002863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008754 - O antigen ligase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HFQ0205109.1"
                     /translation="MNRIVPVLEKSLLSRDAFRVINLIICLLYFMPSTFNVTNIPMKI
                     AFAWGGIIVLYEVFIKKNFFKMRFSWLLIGAMISFILTIIINRENFLIPSIYNFGYLL
                     ITLIVIFPADFSQSEEEKKKKMVYFNNVFIIIIFLAALISIYQFIFLISYHVPTGTPG
                     LLARQGFIEHRLFGVYTSPNVGAMFGYTSIILSLISVLISKITKTIRVFYMMNFIVQI
                     FYITLSSSRGAQVVICSFLVLFLLLFANSKFRKSIREVLPVKIKWMVSILLVLLVYFS
                     FGTNYAKDFLATIPVSIDRKVEVIESNESDKTPLPEKEVILQHSSDNSEISAGRFTIW
                     KAALKVIRPTLLFGYGETDFYGNSDAKFLKKVDLDTTDVNELKRAHGNMHNGFLQVLV
                     SSGIIAFICIYAFYVLNIFSLLKTFFRSKVNYAFLGIVLIFILSIFIDEMVEAHVLFN
                     KRDVISIVFWYYLGSISYLYLKKEN"
     gene            3285..>3655
                     /locus_tag="ACG8LA_002864"
     CDS             3285..>3655
                     /locus_tag="ACG8LA_002864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0205110.1"
                     /translation="MKTAFIAWTPLHLINILNVYQNFYRESKGDLFIYSEFENARRYS
                     ERIKELGLFNDVVFVNHRKIGSSFKRKINLLTNHNQFFSDDLSVYDEIFIQGENYFTK
                     ILFSNVYKKNPDVKLNYIEDG"
BASE COUNT         1329 a          416 c          610 g         1300 t
ORIGIN      
        1 aatagaagtg aataagttac taaaaaaaga atctttttct atagttcaca atcaggttta
       61 ttttggcggg ggaattaatt tatggttagc caaaaagaat ggaatcagac agagaattgc
      121 tcatagccat gcaactgaag atggaaaatc tcaaaatatt gtaatgaatg tattgcgtaa
      181 atttttaacc aaattgttgt tacaaaatgc aacagactac cttgccgtta gtcaagaagc
      241 tggtgaaagt ctgtttcaaa accacccctt tgagatagtt cataatggta ttgatttaga
      301 gctttatagt aaaaattcag aagctaaggt taataagaga aaagaattgg atatctcaat
      361 gagtactttt gttgtgggaa acattggacg attagagaaa caaaaaaatc aatcttattt
      421 gttagagatt tttttagaaa tactaaaaat gaattctgat tcttacttga ttttagtagg
      481 tgaagggtca cttagaaata aactgaaagc caaagcagta gaattggata tagagaaaag
      541 agtaaaattt ttaggagaaa gaaacgatat tcccgagtta ttatctgtga tggatgtttt
      601 tgtaatgcct tctctttatg aaggtctgcc aatggttgga ttagaagcac aagcagcaaa
      661 attaaaatta gtcttagcag atactatttc caaagataca aagttaacaa ataatgtgga
      721 ttttgtatca ttagatgaaa caccacaaga atgggcaaaa aaagtaataa aagagccgta
      781 tgctaataaa ataacacaag aactaaagag ttatgatgtt tcgtacacta ctgaacaaat
      841 ggagagtata tatagtagag atcattaaaa atgttcaaga tattttagga gtgattattt
      901 ttgaaaatat gttatttgat attggcatac aatgatattg gcaacttaaa gagattggtc
      961 aatcgattga acgaaaatgc agtttttatt attcatatag ataaaaaaac tgatatagaa
     1021 ccatttattg aagcatttaa atcatatgat aatgttgaat ttttatgtaa taaaaaccgt
     1081 gttaaaattt attggggtgg tttttccatt gtacaagcag aaatcaattt agtaaagaga
     1141 gcattacaaa atgagaaata tttaaaatat gtattattat ctggtgctga ttatccaatc
     1201 aaagataatg agtatattta taattatttt aaaaagaata gttcagtgga gtttattcgt
     1261 ggaatagatc tagatcaaat taaacataaa gaattttatt ataaacatat agatgtatat
     1321 caaaaacatg attatcctag aattaatagg aataacacaa ctgcatttaa aatttttaga
     1381 gctataatta atcgttgtct gaggatgatt aaacttcccc caaaaattag acaccataaa
     1441 tttgatttgt atcatggttc tcaatggtgg gctttgtcga aagaatgcct aacagaatta
     1501 atacaaatgt atgaacaaaa tcaacaagac tacctgaatt ttaaaatagg tatgtttgcc
     1561 ccagatgaaa aattttttca tacacttttt tttaattcct cgttcaaaaa taaaaatgtt
     1621 attggaggac cagatttacc acttgaattg aaaaatattg aagaaactac tttacaaact
     1681 tcgaaattag caaatattca tattattgat ccttccatga acaaatggtt tgatgaaagg
     1741 gatatagatc aaataaaaga aagtgaaaaa ttatttgtaa gaaaagttaa atcggattac
     1801 tctgataaac tattaaatag aattgataaa gaaattttga aagttggaaa tatagatgaa
     1861 tagaatagta cctgttttag agaagagttt attaagtcga gatgcgtttc gagtaataaa
     1921 tttaatcatt tgtctgcttt attttatgcc tagtactttt aatgtaacta atatcccgat
     1981 gaaaatagct tttgcttggg gtggaattat agttttgtat gaggttttta taaagaaaaa
     2041 tttttttaaa atgcgttttt cttggctact gattggagca atgattagtt ttatcttaac
     2101 tataatcatt aacagagaaa attttttaat tccatctatt tataattttg gatatttgct
     2161 gattactttg atagtaattt ttcctgcaga cttttcacaa agtgaagagg aaaaaaagaa
     2221 aaaaatggtg tattttaata atgttttcat tatcataatt tttttagctg cgctaatatc
     2281 tatctatcaa tttatttttt tgatttctta tcatgtccca acaggaacgc caggattact
     2341 tgcaagacaa ggttttattg aacatcggtt atttggtgtc tatacaagtc caaatgttgg
     2401 agctatgttt ggatatactt ctattatttt aagtttaatt agtgtattaa tttcaaaaat
     2461 aacaaaaacg attcgtgttt tttatatgat gaattttatc gtacaaatat tttatattac
     2521 actttcttcg tctagaggtg cccaggtagt aatttgttct tttttagtat tatttctttt
     2581 gttgtttgcc aattcaaaat ttagaaagag cattagagaa gtactacctg taaaaatcaa
     2641 atggatggta agcatattat tagttctatt ggtatatttt tcttttggta ctaattatgc
     2701 taaggatttt ttagcaacaa ttcctgtatc gattgataga aaagtagaag ttatagagtc
     2761 aaatgaatca gataaaactc cacttccaga aaaagaagta atattacagc attctagtga
     2821 taactccgaa atttcagctg gtcgttttac gatttggaaa gctgcgctta aagttataag
     2881 accaactttg ttatttggtt atggagagac cgatttctat gggaatagcg atgcaaaatt
     2941 tttgaaaaaa gtagatcttg atactacaga tgtgaatgaa ctaaaaagag cacatggaaa
     3001 catgcataat ggatttcttc aagtacttgt atcaagtggt ataattgctt ttatatgtat
     3061 ctatgctttc tatgtgttaa atatctttag tttactcaaa acatttttta gaagtaaagt
     3121 gaattatgcg tttcttggta ttgttttaat ttttatacta tctattttta tagatgaaat
     3181 ggtggaggct catgtacttt tcaataagcg cgatgtcatt tcaattgttt tctggtatta
     3241 tttgggaagc atttcttact tgtatttaaa aaaggagaat taatatgaag acagctttca
     3301 ttgcttggac tcctttacat ttgattaata tattaaatgt ttatcaaaat ttttaccgag
     3361 aatcaaaagg agatttattt atttattctg aatttgaaaa cgctagaaga tatagtgagc
     3421 gtataaaaga attagggcta tttaatgatg ttgtttttgt gaatcaccgg aaaatcggtt
     3481 cttcctttaa acgtaaaatt aacttgttaa ctaaccataa tcaatttttc tcggatgatt
     3541 tatccgttta tgatgaaatt tttatacagg gggaaaatta tttcacaaaa atacttttct
     3601 ccaatgttta caaaaaaaat ccagatgtaa aactaaatta tatagaagat ggttt
//
LOCUS       DAZKKZ010000133         3605 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.141, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000133 DAZKKZ010000000
VERSION     DAZKKZ010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3605)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3605)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3605
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.141"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..189
                     /locus_tag="ACG8LA_002865"
     CDS             <1..189
                     /locus_tag="ACG8LA_002865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFQ0205111.1"
                     /translation="LVEDASLSGENERINELIEFIRKNKFRTLEYDDKLVRKIIQSVT
                     VYEGHFVIAFKSGIEMEI"
     gene            332..556
                     /locus_tag="ACG8LA_002866"
     CDS             332..556
                     /locus_tag="ACG8LA_002866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018579902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0205112.1"
                     /translation="MTTAEMIKELCEQMNISVSELARRIGQTPQNFNKKLQRETVTLD
                     ELKAIADVLGVKFVQAFILPDGEEIKISNE"
     gene            571..1440
                     /locus_tag="ACG8LA_002867"
     CDS             571..1440
                     /locus_tag="ACG8LA_002867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HFQ0205113.1"
                     /translation="MVGNVIQIVTEKLSSLPFIEGIVLGGSRARGTHTENSDIDIGIY
                     YNSDSFDLTAINQIATELDDKNRNNLVVPPGAWGDWINGGGWLFINGYHVDLILRDIK
                     RVEQIIKDTEQGIVTANYQTGHPHGYISAMYRGELAISKILYAKNESLCELKKQAEIY
                     PTALKKSLMNFFIFEAEFSLMFVKANAGVEDKYYIAGHVFRIISCLNQVLFACNNAYC
                     INEKKAIKLLETFEYKPEKYAERVNHIFEVLGLSLFECYDMTEKLYKEVNEIVSEINN
                     FLNEESSDERKQI"
     gene            1421..2155
                     /locus_tag="ACG8LA_002868"
     CDS             1421..2155
                     /locus_tag="ACG8LA_002868"
                     /EC_number="2.1.1.222"
                     /EC_number="2.1.1.64"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008425 -
                     2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0061542 - 3-demethylubiquinol-n
                     3-O-methyltransferase activity [Evidence IEA];
                     GO_function: GO:0102208 - 2-polyprenyl-6-hydroxyphenol
                     methylase activity [Evidence IEA];
                     GO_process: GO:0006744 - ubiquinone biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFQ0205114.1"
                     /translation="MKENKYDDNIFFQKYSQMSRSQKGLAGAGEWETLKKMLPDFKGK
                     RVLDLGCGYGWHCIYAMENGASSVVGVDISHKMLEVAKGKTHFPQIEYECCAIEDVDF
                     PEESFDVILSSLAFHYVADYENLIKKIYRMLKAGGNLVFTVEHPVFTAHGTQDWYYNE
                     KGEILHFPVDNYYYEGKRTAMFLEEKVTKYHRTLTTYLNTLLSNSFIINQIVEPQPPE
                     NMMDIPGMADEMRRPMMLIVSAKKKM"
     gene            2188..3096
                     /locus_tag="ACG8LA_002869"
     CDS             2188..3096
                     /locus_tag="ACG8LA_002869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside nucleotidyltransferase ANT(6)-Ia"
                     /protein_id="HFQ0205115.1"
                     /translation="MRSEKEMMDLVLSLAEQDERIRIVTLEGSRANINIPKDEFQDYD
                     ITYFVSDIEPFISNDDWLNQFGNIIMMQKPEDMELFPPEEKGFSYLMLFDDYNKIDLT
                     LLPLEELDNYLKGDKLIKVLIDKDCRIKRDIVPTDIDYHVRKPSAREYDDCCNEFWNV
                     TPYVIKGLCRKEILFAIDHFNQIVRHELLRMISWKVGIETGFKLSVGKNYKFIERYIS
                     EDLWEKLLSTYRMDSYENIWEALFLCHQLFRAVSGEVAERLHYAYPEYDRNITKYTRD
                     MYKKYTGKTGCLDSTYAADIEERREQ"
     gene            3093..3573
                     /locus_tag="ACG8LA_002870"
                     /pseudo
     CDS             3093..3573
                     /locus_tag="ACG8LA_002870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
BASE COUNT         1252 a          521 c          789 g         1043 t
ORIGIN      
        1 ttagtagaag atgcctccct cagtggcgag aacgagcgaa tcaatgagct gattgaattt
       61 atccgcaaga acaaattccg caccttagaa tatgatgata agcttgtaag gaagataatc
      121 cagagcgtta cagtctatga aggccacttc gtcatagcct tcaaatctgg catcgaaatg
      181 gaaatatgaa aaccagaagt aaatagccca tgactctaca gtagagttgt gggttttctt
      241 ttgcttgctg attataataa tattttaata actattgtgt ttatcaacca aatggtttat
      301 aatattctta gcgtaaactt ggaggtgctg tatgactacg gcagaaatga ttaaagaact
      361 gtgtgagcaa atgaatataa gtgtttccga acttgctaga cgtattggcc agactccaca
      421 gaatttcaat aaaaaattac aacgagaaac agtaaccttg gatgagttga aggccattgc
      481 tgatgtgcta ggtgtcaagt ttgtgcaggc atttatttta ccagatggag aagaaataaa
      541 aatatctaac gaataaagga ggatgtttat atggtaggta atgttattca aatagtaaca
      601 gagaaattat catctttgcc ttttatagaa ggcatcgtat tagggggctc acgtgcaaga
      661 ggcacccata cagaaaattc tgatatagat atcggaatct attacaattc agactcattt
      721 gacctgacag cgattaatca aattgctaca gaattggatg ataaaaatag aaacaacctt
      781 gttgtgcctc ccggagcgtg gggtgattgg attaatggcg gcggatggtt atttataaat
      841 gggtatcatg ttgacttgat tttacgtgat ataaaacggg tagaacaaat aatcaaagat
      901 acggagcaag gaattgttac tgccaattat cagaccgggc atccccatgg ttatataagt
      961 gcaatgtatc gtggagaatt agcgattagt aaaatactat atgctaagaa cgaaagctta
     1021 tgcgaattaa aaaagcaggc agaaatttac cctactgctc taaagaaaag cttgatgaac
     1081 ttttttatat ttgaagctga attctcttta atgtttgtaa aagcaaatgc gggggtagag
     1141 gataaatatt atattgcagg ccatgttttt cgtattattt catgcttaaa tcaagtacta
     1201 tttgcatgta ataatgctta ttgcattaac gaaaagaaag ctataaaact gcttgaaact
     1261 tttgaatata aacctgaaaa atatgccgaa agagttaatc atatttttga agtactcggt
     1321 ctttctcttt ttgaatgcta cgatatgacc gagaaacttt ataaagaagt gaatgaaatt
     1381 gtatcggaga taaataactt tttaaacgag gagagttcag atgaaagaaa acaaatatga
     1441 tgataatata ttttttcaaa aatacagtca aatgagtcgc tcgcagaaag gactggctgg
     1501 tgcgggagaa tgggagactt tgaaaaagat gctacctgat tttaagggta agcgtgtgct
     1561 tgatttagga tgcggctatg gatggcactg tatatatgcg atggaaaacg gtgcttcctc
     1621 tgtagtaggt gttgatattt ctcataaaat gctcgaagta gcaaaaggaa aaacccattt
     1681 tccacagatt gaatatgaat gctgtgccat agaagatgtg gatttcccag aggagagctt
     1741 tgatgtaata ctaagttcgc ttgcgtttca ttatgtagca gactatgaga atttaataaa
     1801 aaagatatat aggatgctga aggctggtgg caatttagtt tttacagttg aacatcctgt
     1861 ttttactgct catggaacac aagactggta ttataacgaa aaaggagaaa tactgcattt
     1921 cccggtggac aattattatt atgagggcaa acggacagct atgtttttgg aagaaaaggt
     1981 tacaaaatat catagaacac tgaccacata tctaaataca ctgctttcaa atagttttat
     2041 aataaatcag attgtggagc cacagccgcc agagaacatg atggatattc cggggatggc
     2101 ggatgaaatg cgacgcccaa tgatgctgat tgtatcggca aaaaagaaga tgtaataata
     2161 tagaaaaaat aaacgaggag tatgtaaatg agatcagaaa aagaaatgat ggatttagta
     2221 ctttctttag cagaacagga tgaacgtatt cgaattgtga cccttgaggg gtcacgcgca
     2281 aatattaata tacctaaaga tgaatttcag gattatgata ttacatattt tgtaagtgat
     2341 atagaaccgt ttatatctaa tgatgactgg cttaatcaat ttgggaatat aataatgatg
     2401 caaaagccgg aggatatgga attattccca cctgaagaaa agggattttc ctatcttatg
     2461 ctatttgatg attacaataa aattgatctt accttattgc ccttggaaga gttagataat
     2521 tacctaaagg gcgataaatt aataaaggtt ctaattgata aagattgtag aattaaaagg
     2581 gacatagttc cgactgatat agattatcat gtaagaaagc caagcgcaag ggagtatgat
     2641 gattgctgca atgaattttg gaatgtaaca ccttatgtta ttaaaggatt gtgccgtaag
     2701 gaaattttat ttgctattga tcattttaat cagattgttc gccatgagct gctgagaatg
     2761 atatcatgga aggtcggcat cgaaacaggc tttaaattaa gtgtaggcaa gaactataag
     2821 tttattgaaa ggtatatatc cgaggatttg tgggagaaac ttttgtccac ctaccggatg
     2881 gattcctatg aaaacatatg ggaagcatta tttctatgcc atcaattgtt cagggcggta
     2941 tccggtgagg tggcggaaag gcttcattat gcctatccgg agtatgatag gaatataaca
     3001 aaatatacca gggacatgta taaaaaatac actggtaaaa ccggctgcct ggatagcaca
     3061 tatgccgctg atatagaaga gaggcgggaa cagtgattac agaaatgaaa gcagggcacc
     3121 tgaaagatat cgataaaccc agcgaaccat ttgaggtgat aggtaagatt ataccgaggt
     3181 atgaaaacga gaattggacc tttacagaat tactctatga agcgccatat ttaaaaagct
     3241 accaagacga agaggatgaa gaggatgagg aggcagattg ccttgaatat attgacaata
     3301 ctgataagat aatatatctt ttatatagaa gatatcgccg tatgtaagga tttcaggggg
     3361 caaggcatag gcagcgcgct tatcaatata tctatagaat gggcaaagca taaaaacttg
     3421 catggactaa tgcttgaaac ccaggacaat aaccttatag cttgtaaatt ctatcataat
     3481 tgtggtttca aaatcggctc cgtcgatact atgttatacg ccaactttga aaacaacttt
     3541 gaaaaagctg ttttctggta tttaaggttt tagaatgcaa ggaacagtga attggagttc
     3601 gtctt
//
LOCUS       DAZKKZ010000134         3484 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.142, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000134 DAZKKZ010000000
VERSION     DAZKKZ010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3484)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3484)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3484
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.142"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            198..393
                     /locus_tag="ACG8LA_002871"
                     /pseudo
     CDS             198..393
                     /locus_tag="ACG8LA_002871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290351.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="addiction module antitoxin"
     gene            complement(1925..2443)
                     /locus_tag="ACG8LA_002872"
     CDS             complement(1925..2443)
                     /locus_tag="ACG8LA_002872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HFQ0205116.1"
                     /translation="MRTYKNKEELKKEINRTYTKYILEFETIPEELKDKRVEEVDRTP
                     AENLAYQVGWTNLILKWENDERNGLSVKTPSDQFKWNQLGELYKWFTNTYAHLPLKEL
                     EEILNRNIDDINMMIDSMSDEDLFTAHKRKWADEATKTAVWEVYKFIHVNTVAPFGTF
                     RTKIRKWKRLAL"
     gene            2810..3058
                     /locus_tag="ACG8LA_002873"
     CDS             2810..3058
                     /locus_tag="ACG8LA_002873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0205117.1"
                     /translation="MVKLKMLYIGLQHRSFFDCALGKKYYEVKIDDDTFLTAHQMKQL
                     QKRNDQLEENLILKKRLPYSRLARRTIKGQDLPEDHPF"
BASE COUNT         1197 a          592 c          511 g         1184 t
ORIGIN      
        1 aaatggtata catgaatagg aaaggaaaca gaaggaggca atcttaattt tttaaattgt
       61 ctaaattata tagaaagaac aatctttcta tataattaga cataagagag actacggttg
      121 atttgatatt aacaagcgta tatgaatgta tatacaaata aaaaagggga gggagaagtt
      181 aaagaaaatt cagagaagtg gggcactcag tagtattaac aatttaaaag gaatttctta
      241 aagaaaatgg gttgcatcct ggagatacaa tttttttaga taaagaaaaa attcaagcaa
      301 caattcaaaa aaatcttaac tgctgagatt gatgtagcaa tatctcaatc atcaacaaag
      361 tacgatcctg cctttcaaaa gcttattgat aaatgtttat tcattataaa aataaaagaa
      421 aaatttatgt cagctttttt catcaaagtg gtaatgataa ttcgtctatt aattgtattt
      481 tttaggaaat atggtataat tgttttaacg aaaaggtaat tcatgataca ccaaaaacca
      541 ctagctggcg ggctagtggt tttcttttac gttctattca gattaacggg taggcttact
      601 gtcttttttg gcaataattt tgcaatcaag ccatttacag atgtaatgcg cggatacttc
      661 tgctaagatt gcaaaaaaca tatcgaaaag gtaattcata atacaacctc ctccccttgc
      721 cataataggc cggggtagca gacagcataa atattatacc ataactgaaa atttcatttt
      781 agtacatttc aatatattga tgaaccagca caataaaaca tgccatgact aacagaaaaa
      841 aacttattaa accagatata acttgtaaac atccaactat atagaaaacg taaattttct
      901 atatagttgg attaagataa cgactattta ttttatcata tttttactat accctatact
      961 tttacttggt atatttatga ataatcgcaa atttacccct atactactag tttgtaagtt
     1021 agattaataa aaatactaaa gttatttgtt cttttattaa atacacctac aacttataaa
     1081 ttgatggtat ttagataaca cgaaagaata aaaataacag ctgatagtaa agtttgttga
     1141 cgattgctac tcaatcgaaa gtgagttagt gcgtatgaac ttgcttctga aaacttatga
     1201 aatgaaagac cttttacatc ttgcagaaat cgttactggg attaaactaa gcaataaaaa
     1261 ctaatgttcc cctcattctt tgaacttcta ctatttgatt tatttattct gataaatgac
     1321 gatttcacct tcaggatctt caaatcccgt atagaattta tttaagatct cttcagtatc
     1381 agtaatagga taggcgatag gccacatacc ctttgatggt tagaataaac tgctcaaaat
     1441 ctgtatcgta tgttggcttt agcatattaa caaaggctat ctccaaatta taaaccataa
     1501 gcgttgaatc gttcttaaca atttcaattc ttcctaaccc aaagtcagaa gatataatta
     1561 ccggacttgc cttacccttc atgtgggttg ttgagattcc atatttaaag ggaattgtcg
     1621 gtactatcgg cggtctgaaa aacatcccaa aaataaaaaa atctttcccc tgctagtctc
     1681 ctaagtccct ttgtagcgga tatggcacca taatctcatt ttatcgaagt gagtcatggt
     1741 ttatctgttg gccaaccaaa attgatacaa tctaacgatg caccctctac ggcattctag
     1801 gggagtgcac ttgcattcac ccaataaaaa ccggcagtta gcaaagaact tatgtagtcg
     1861 tatgttctta ctgttaacat acaagaggtc tcctttccac aattgcttag cagtaaacgg
     1921 gaatttacaa agctaatctc ttccattttc ttatctttgt tctaaaagtc ccaaatggag
     1981 caactgtatt tacatgaata aatttatata cttcccatac agccgttttg gttgcctcgt
     2041 ctgcccattt tcttttgtgt gcagtgaata gatcttcatc actcattgaa tcaatcatca
     2101 tgttaatatc atcaatatta cgattgagaa tttcctctaa ttctttcaat ggtagatgtg
     2161 cataggtatt tgtaaaccac ttatataact ctcctaactg attccattta aattgatcag
     2221 aaggcgtttt aacagataat ccatttcttt catcattttc ccattttaga attaaattcg
     2281 tccaaccaac ttgatatgct aaattttcag caggtgttct atccacttcc tcaactcttt
     2341 tatccttcaa ttcttcagga atagtttcaa attctaaaat atatttagta taagtcctat
     2401 ttatttcttt ttttaattct tctttatttt tatatgttct cattatatta cctccataaa
     2461 ttcctaattg tctcctttaa ttcatctata atttcatcca cgatatttta atccgttcta
     2521 caatgcatat ctgatatgca ttgactgtct aactcatatg tgaatgattt ataaaatatc
     2581 ccaacgtctc atctaaagaa atgttgatcg tcagcaagga gctaaaaaat acgaatatat
     2641 ttcttttgta gtaaaatcgg actggtttgc atatcatttt cttcgtaaat atcaaaatca
     2701 tgttaactac tatcaattac taataaaaac taccacttta agcgttaaga actgttaagt
     2761 ttagttaagt gaggatagtt cacaaaatcc attgttaaac ttcacgaaag tggtaaaact
     2821 caaaatgctt tatataggat tacagcatcg ctctttcttc gattgcgcgt tgggtaaaaa
     2881 atattatgaa gtaaaaattg acgatgacac gttccttacg gctcatcaga tgaaacagct
     2941 acaaaaacga aatgatcaac tcgaagaaaa tttaattcta aaaaagcgat tgccatattc
     3001 acgcctcgct cgacgaacta ttaaaggtca agatttacct gaagatcatc ctttttagga
     3061 aattgaagct ttttatgttg cacaatgcat ttataatact acaatgatgt tttcaccaga
     3121 tattcttcta gggtgcggtg taatgaaaca gatacacttg caaaagaaaa ttcaccgcga
     3181 atttactaaa attatgaata attatgttaa tcttccgaaa tttttttcca aaattaaggg
     3241 atcaagctgg tgttatagat tgtttaaggt tggcaaaaaa ataacttctt tttaaacaat
     3301 tatagaaaac cgatactctg ttaagttggt tgacacggtg tcgattttta tgactttctt
     3361 attctgaaac ttcactaacg gacagtacct aaaaagtcta tagtatggac gtttacgagt
     3421 actattttat caaaaatgct gctcatttca acttatatgt tttagtgaac tacccccact
     3481 tagc
//
LOCUS       DAZKKZ010000135         3367 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.143, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000135 DAZKKZ010000000
VERSION     DAZKKZ010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3367)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3367)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3367
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.143"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            131..448
                     /locus_tag="ACG8LA_002874"
     CDS             131..448
                     /locus_tag="ACG8LA_002874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HFQ0205118.1"
                     /translation="MLFYSNFILIVAILLLLNIWIFDRSRNSSIGFRTKRSLSSKKNW
                     VYSQTIFYGGIVLISLLSSTLYSLNIIDVSTSNSISIIGIIIAAIITQLFLVFGEKKR
                     SKK"
     gene            complement(539..904)
                     /locus_tag="ACG8LA_002875"
     CDS             complement(539..904)
                     /locus_tag="ACG8LA_002875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0205119.1"
                     /translation="MIKTCWKNLPLLLSFVPYVHFALLLDFRYHSVSGFITLIFLSLF
                     AGYYFQRNRRIISLFIANIISTVTSYLFCANFTEWRYFYHPLKPTQLILLLAGIYLVP
                     QILGSLWAVALSYKKARHP"
     gene            1112..1594
                     /locus_tag="ACG8LA_002876"
     CDS             1112..1594
                     /locus_tag="ACG8LA_002876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0205120.1"
                     /translation="MRRKAVIDRLYLFFWFFPIVLLPFTWVNAVVQGAEILGLIQGSG
                     FVVSRNFPALIVFYLVISVGLLLPKSLINHYNWQLLYFSCLLVFTSMFSLLPRLIIGP
                     NGLSESGLKDLAYSSMYFLTIKPWFYLVIASFILATFFYFWTEIRIKSERSVSIKNNY
                     "
     gene            1791..2681
                     /locus_tag="ACG8LA_002877"
     CDS             1791..2681
                     /locus_tag="ACG8LA_002877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042301 - phosphate ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS family protein"
                     /protein_id="HFQ0205121.1"
                     /translation="MKKVLFTLGMMGILLAGCGSGSGNTDGSATQNNSSDSNEQVKIV
                     AVGSTALQPLVDAAQESFVQENPNYQISVQGGGSGTGLSQVEAGAVTIGNSDVFAEER
                     DGVDASKLVDHKVAVVGMAPIVNKDTDVKDITKQELIDIFTGKITNWKEVGGKDQKIN
                     VVNRANGSGTRATFEKWGLDGATPVQSQEQDSSGTVRQLVSQTPGAISYLAFSYLDDS
                     TQALSIDGVEPKEENVADNSWGIWSYEHMYTNGKPSPEVQKFLDYMMTEEIQEGPVKE
                     LGYLPITMMEVERDHEGNIK"
     gene            complement(2968..>3367)
                     /locus_tag="ACG8LA_002878"
     CDS             complement(2968..>3367)
                     /locus_tag="ACG8LA_002878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFQ0205122.1"
                     /translation="EPLKRHYHRLFKRPISQTEIVDELLSYNEELRTAYHFCQLLRYY
                     FVKRGTEGFQETLKTISSTLPQSFKKKFTIFHCYQSGISNAFKVSHSNGVTEGLNNKI
                     KLIKRIAFGYRNFYNFRARIYLQQGLIFEN"
BASE COUNT         1133 a          536 c          649 g         1049 t
ORIGIN      
        1 taactatgca ctgtaacgat aatgctgcta aaatatcttt ttacgaaaaa catcacaagg
       61 aaaaacttaa ctatggtatt atctaaacat aattttttcg gtatttaata tttaattagg
      121 aggtaatatt ttgctttttt atagtaattt tatcttaata gtagcgatat tattacttct
      181 gaatatatgg atttttgata ggagtagaaa ttcaagtata ggttttagaa ctaaacgaag
      241 tttgtcttct aaaaaaaatt gggtatactc acaaactatt ttttatggag gaattgtttt
      301 aattagttta ctttcttcaa cactttattc tttgaatatt atagatgttt ccacctcaaa
      361 ttcaatatct attattggaa tcattattgc tgcaattatt acacaactgt ttttagtgtt
      421 tggagagaag aaaagaagta aaaaatagaa aaactagtga tagttttggt gatataagaa
      481 aaacatatat gtataaaaag aagaaagtag cttctctttg tacatatatg gtttgttttt
      541 atggatgccg agctttttta taagataagg ctaccgccca taacgaccca aggatttgtg
      601 gaactaagta aatacctgca agaagcaaga tcagctgggt cggttttaaa ggatgataga
      661 agtaacgcca ttcagtaaaa ttggcgcaaa ataaatagga agtgacagta gatataatat
      721 tggcaatgaa taaagatata atacgcctgt tcctttgaaa ataatatcca gcaaaaagag
      781 ataaaaatat caatgtgatg aacccgctta cggaatgata acgaaaatca agcagtaagg
      841 cgaaatgcac ataaggaaca aaagataaaa gcaacggaag gtttttccag caagttttta
      901 tcatctttca tcaccaccta acaagtgtta ttattttgtt agttttattg taaattgaat
      961 cctgcaataa tcaattactt tttcattatt tctagattaa atgaataaac tctcatgcca
     1021 ttatctctaa aaaaaaagtt tttcccccta atttttttag atagaaaatt gtatagtatg
     1081 atgagagaaa aagtagtttg ggggaacgtt aatgagaaga aaagcagtaa tcgatcggct
     1141 ttatttattt ttttggtttt ttcctatcgt tttgctacct tttacatggg taaatgctgt
     1201 tgtacaaggt gcggagatat taggcctgat ccaaggaagc ggatttgtgg tttctaggaa
     1261 ttttccagct ttgattgttt tctatttagt gataagtgta ggtctcttat taccaaaatc
     1321 tctgatcaat cactacaatt ggcagctgct ttacttttct tgcttattag tatttacatc
     1381 tatgttttct ttgctgcctc gcttgattat cggccctaat ggtttgagcg agagtggatt
     1441 gaaggattta gcttattcct ccatgtattt cttgacgatc aaaccatggt tctatttagt
     1501 aattgcctca tttattcttg caacattttt ttacttctgg acagaaatca ggataaaaag
     1561 tgaacgatct gtatctataa aaaataacta ttgatggtgg atcatcagta aaaaaacata
     1621 tgagctgcgt aaaatgcatg tttctcatat gcttttttta ttattatgta aagaatgcga
     1681 aaaacgttta catgattttt acataactta actatatttt tacagcaacc atacgaggga
     1741 tttacagtcg actgataaac tttagttgta aataagaaag gagcaataaa atgaaaaaag
     1801 tattgtttac tctaggtatg atgggaattc ttttagccgg atgcggctca ggatcaggaa
     1861 atacagatgg ctctgccaca caaaataatt caagtgactc aaatgaacaa gtaaaaatcg
     1921 ttgcggtagg ttcgacagca ttacagccgt tagtcgatgc agcacaagaa agctttgtac
     1981 aagaaaatcc aaattatcaa atctctgtac aaggaggagg aagcggaact ggtttgagcc
     2041 aagtcgaagc tggagcagtt actatcggaa actctgatgt atttgcagaa gaaagagacg
     2101 gagttgatgc ttcaaaatta gtggatcata aagtagcagt ggtcgggatg gcaccaatcg
     2161 tcaataaaga tacagatgtc aaagatatca ccaaacagga attgattgat atctttacag
     2221 gaaaaatcac taactggaag gaagttggcg ggaaagatca aaaaatcaac gtcgtgaacc
     2281 gtgcaaacgg cagcggtacc cgcgcgacat tcgaaaaatg gggactggat ggtgctaccc
     2341 ctgtgcagtc ccaagaacaa gattcatcag gaacagttcg gcagctggta agtcaaacac
     2401 caggagcaat cagctattta gctttctcat atctcgatga ttccacacaa gcactaagta
     2461 tcgacggtgt agaaccaaaa gaagagaatg tagcagataa cagctgggga atctggtcat
     2521 atgaacatat gtacacgaac ggaaaacctt cccctgaagt ccaaaaattc ttagactaca
     2581 tgatgacaga agaaatccaa gaaggacctg tcaaagaatt gggctattta ccaatcacaa
     2641 tgatggaagt agaacgtgat cacgaaggaa atatcaaata actagcagat aaacatgcca
     2701 cggtagtcgt tactattaag gaaaaatcaa ctatgtttcc ccacatatac atttttcctt
     2761 taattgtgaa aaatagttcc tcatattttg ccgttttttg agctaatacc gagggtcagc
     2821 tgattgaaca ccgtttattc gaaaaaaaga gctacgacat agaactgtcg taactttttt
     2881 tggctcttcg tcaaatcgtg ttggtgaaga caaatttgaa taaaacttag tccgatatgc
     2941 ggcgcgttct gtgcgccgca tattttttta gttttcaaag atcagacctt gttgtaaata
     3001 gatccgtgcc cgaaagttat aaaagttgcg ataaccaaac gcaattcgtt taatcagctt
     3061 gatcttgtta ttcagcccct cagtgacgcc gtttgagtgg gacaccttaa aggcatttga
     3121 aatacccgat tggtagcaat ggaagatcgt gaatttcttt ttaaacgact gaggtaacgt
     3181 agatgaaatt gttttaaggg tttcttgaaa gccttccgta cctcgtttaa cgaaataata
     3241 gcgtaataat tgacaaaaat gatacgcagt tcgcaattct tcgttgtagc ttaacagctc
     3301 atcaacgatt tctgtttgac taattggtcg tttaaacagt cgatgataat gccgtttgag
     3361 tggctcc
//
LOCUS       DAZKKZ010000136         3290 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.144, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000136 DAZKKZ010000000
VERSION     DAZKKZ010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3290)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3290)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3290
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.144"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            177..773
                     /locus_tag="ACG8LA_002879"
     CDS             177..773
                     /locus_tag="ACG8LA_002879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VTT domain-containing protein"
                     /protein_id="HFQ0205123.1"
                     /translation="MNIAASRKLINFISIIGLGLSIALTIYFINLGVFKDLNALRGLV
                     GDSIILGPIIFVFIQILQVVIPIIPGGISTAAGVLIFGPYAGFIYNYIGICIGSIIIF
                     LLGRRYGKPFILSMISDKTYNKYIGWLDNQNRFEKLFALAIFLPVAPDDALCLMAGLT
                     NMSVKRYTLIILIAKPLSIFLYSMALIYGGQYLSGLLG"
     gene            897..2696
                     /locus_tag="ACG8LA_002880"
     CDS             897..2696
                     /locus_tag="ACG8LA_002880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphoryl diester phosphodiesterase
                     membrane domain-containing protein"
                     /protein_id="HFQ0205124.1"
                     /translation="MNYLKRSLGNAWDFLKGTQAYFRDVLLMHGFILFICLPLLSSTT
                     RFILHRGAIDYLSYDNIPSIFSQHPGVLLSLIVVLMTILLLVYFEFTFLLMSVFFIKK
                     KEPISLKQLLHLTILQLKKVRPITFLFFLAYFLLILPISGLSFNSDLLSKIKIPAFIM
                     DFIFANRWIIVSSFLLVYIFLGYIGIRLIFALPEMILRDRPFRAAIRESWSLTKSRLL
                     AITGQFIVIGGTILLLSSLGYIVVILAQSMVEQFFPDYALISAVFAMTLLQGILLFNI
                     VMSTVGIFYIIVDFMDDEGFLPEIPKWFIPQAPNLRFSALKNTGLTLFAVFFGIGVCL
                     YNMDYLTSAVQTKPVTVSHRGVSTQNGAQNTLEALEKTSRDYHPDYVEMDVQETKDGH
                     FVVMHDANLRHLTGVNGTPQDLTLKELTNLTVTENGVQAPVCSFDSYLEKAHKLNQKL
                     LIEIKTSKKDSDDLVERFVHKYRKVILENHHILQSLTYQTVSDLKEAEPNFYVGYILP
                     FNIVGPPVTPADFLTMEYSTINRNFINSAHQDGKEVYVWTINDSDAMSRMMFYGVDGI
                     ITDEMGLLNESMKQTDEEITYSDKLLNFVLGVG"
     gene            complement(2974..3186)
                     /locus_tag="ACG8LA_002881"
     CDS             complement(2974..3186)
                     /locus_tag="ACG8LA_002881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0205125.1"
                     /translation="MVKAEVGRSYICKPIGVSHELIGCIERTYINTAVVYVESYDQRD
                     YQLINESKYRMLVKFCDISAPAELVS"
BASE COUNT          926 a          580 c          593 g         1191 t
ORIGIN      
        1 taaaaaaaac aagttattaa ataagtcttt agttggatgt ttttttgaga tcaatctttt
       61 atacttatga tgaacttaca aaattgtttg ttttctgtca tatcaaaaaa tggcgcagtt
      121 agttgctttt ctagtaaagt atagttaaca aagaacctct aaggagttga tgaataatga
      181 atattgctgc ctctcgaaaa ctgataaatt tcatatccat tatcggatta ggcctatcaa
      241 tcgcgctgac gatttatttt attaatttag gtgttttcaa agatttgaat gcgttaagag
      301 gattagtagg tgattccatc attttaggac cgattatttt tgtcttcatc caaatcctgc
      361 aagtagttat tccaatcatt cctggaggga tcagtactgc agctggtgtc ctgatatttg
      421 gcccttatgc tggatttatc tataactata ttggaatctg cattggttcg attatcattt
      481 ttctgctagg gcgtcgttat ggaaagccat tcatactttc catgattagc gataagacat
      541 ataacaaata tattggctgg ctggataatc aaaaccgttt tgagaagctg tttgctctag
      601 ctatttttct tccagttgct cctgacgatg cgttatgttt gatggctgga ttgacaaaca
      661 tgtcagtgaa acgatataca ctaatcattt tgattgctaa accactgtcg attttcttat
      721 atagtatggc cttgatttat ggaggtcaat atctaagtgg tcttcttgga taatatttat
      781 tttgtaaaat tagtcattga ttgacaatgt taaatctggg aaagggtctg caaaacacac
      841 tgcacccttt cctttttcat tagatttgcg ctacaatgtg aagagcaggt gataggatga
      901 attatttgaa acgtagctta ggtaatgctt gggacttttt aaaaggaaca caagcttatt
      961 tccgtgatgt cttgctgatg catggcttta ttttatttat ttgtttaccc ttattgagca
     1021 gtacgacccg ttttatttta caccgagggg caattgacta tttgtcttat gacaatattc
     1081 cttcaatttt ttctcaacat cctggggttc tactctcgtt aatcgtagtt ttgatgacga
     1141 ttttactgtt agtttatttc gaatttactt ttcttttgat gagtgttttt tttattaaaa
     1201 agaaagaacc aatctctttg aagcaactct tacacttgac gatacttcag ctgaagaaag
     1261 tgagacccat tacttttttg tttttccttg cttatttttt attgattcta ccgatcagcg
     1321 gattaagttt taattctgat ctactgtcaa aaataaaaat ccccgctttc attatggatt
     1381 ttatttttgc taatcgttgg atcatcgtca gttccttttt actcgtttat attttccttg
     1441 gctatattgg gattcgactg atttttgctt taccggaaat gattctacgg gatcgtcctt
     1501 ttcgagcagc cattcgggaa agctggtcat tgaccaaatc gcgtcttttg gccatcacgg
     1561 gccaatttat tgtgattggc ggtacgattt tactcctttc ttctttagga tatatcgttg
     1621 ttattttggc acaaagtatg gttgaacaat ttttcccaga ctatgcattg atcagcgctg
     1681 tgtttgctat gacgctttta caagggattt tattattcaa tatcgtgatg tctaccgtag
     1741 ggatttttta tatcattgtt gatttcatgg atgacgaagg cttcttgcct gagatcccta
     1801 agtggtttat cccacaagcc cccaacttgc gtttctctgc gctgaaaaac actggtttga
     1861 ctctttttgc agtttttttc ggtattggcg tctgtcttta caatatggat tatctgactt
     1921 cagctgttca gacaaaacca gtgactgtct ctcacagagg tgtgagtacc caaaatgggg
     1981 cgcaaaatac tttagaagca cttgaaaaaa caagcagaga ctatcatcct gattatgtag
     2041 agatggatgt tcaggaaaca aaagatggtc atttcgtagt gatgcatgat gcaaatcttc
     2101 gtcacttaac aggggtaaat ggaacaccac aggatcttac attgaaagaa ttgacaaatc
     2161 ttacagttac tgaaaacgga gtgcaagccc ctgtttgttc ttttgattct tatttggaaa
     2221 aagcacataa gctaaaccaa aaattactta ttgagatcaa gacctctaaa aaagattcgg
     2281 atgaccttgt cgaacgattt gtccataaat accgcaaagt tatcttagag aaccatcata
     2341 ttttgcaaag tttgacgtac caaaccgttt cagatttaaa agaagcagaa ccaaactttt
     2401 atgtgggcta catcttacct ttcaatattg ttgggccccc tgtgacgcct gctgattttc
     2461 tgacaatgga atatagtacg atcaaccgta acttcattaa ttctgcccac caagacggaa
     2521 aagaagtata tgtatggaca atcaacgatt cagatgctat gagtcgcatg atgttttatg
     2581 gtgtggatgg tatcataacc gatgagatgg gactactaaa tgaaagtatg aaacaaacag
     2641 atgaagaaat cacttattca gataaactgc taaattttgt tttgggagtc ggctaatcaa
     2701 aaatcgttaa tgaaaaaagt ctttatacaa caaaaaacgc ataacctgcc accgcaggta
     2761 tatgcgtttt ttgtttgacg ctcataatgt gtgcttaact ttctcttgat tccttcatcg
     2821 cacgaacaat agctaaaata gcaggaattg cagagatcac tgcaagaata attcccattt
     2881 tccctgaact ttttcttttt ggcatatctt ctcgctccct tctgtcttta tttatattat
     2941 aagggagttc ttgcgaattc tcaaaaatac tgtttaagaa accaattcag caggtgcgct
     3001 aatatcacag aattttacga gcatgcgata cttgctttca ttgataagtt gatagtctcg
     3061 ttggtcataa ctttcaacat acacgacagc cgtgttgata tatgtacgtt caatacagcc
     3121 gattagttca tgagatactc cgatcggttt gcatatataa gatcttccta cttctgcttt
     3181 taccatttca ttccctcttt tctttatttt tattttgttt tttctttatt ttataataac
     3241 aaattacctt gtatttgaaa acgtttttat ccattttttt attttttatt
//
LOCUS       DAZKKZ010000137         3290 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.145, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000137 DAZKKZ010000000
VERSION     DAZKKZ010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3290)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3290)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3290
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.145"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(554..2167)
                     /locus_tag="ACG8LA_002882"
     CDS             complement(554..2167)
                     /locus_tag="ACG8LA_002882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HFQ0205126.1"
                     /translation="MKVVVIGGVAGGPSFATRFRRLNEAHEIIIYERGENISYASCAL
                     PYYLGGVITDRDSLIERTPEILKTKNNIDVFTKHEVTAIDPSTKRLTVKDLSTNEEIK
                     TDYDKLIISSGARPDYPDIPGVFEAENGFVLRSVTDADRIKSFLEEKNPQHVVILGAG
                     VMGLELAENFKHRGLDVTLIDQLPQVAFPYDPEIANLVYDKLLKEGLAVHLETRVTEI
                     RDKGREIVLSDGSVLSADMLIFAVGVSPKNEVVKATGIQLSDTGQIIVDDQLQTNLPD
                     IYAIGDIIETTSVVTGQPIQSMLSSAANRQGHMLADILNGTPMRYRGYIGAGVAKIFD
                     HTASYAGMTEHELKASGITNYKTVFITPFDHAYFYPEATRLNLKLIFDADSGRILGGQ
                     AFGEKGVDKRMGELSVAITGNLTVFDLPDLELPYSPPYSTTRDPLNIAGYVAINQMTN
                     IVETIKASDIPENDLKEAFFLDIREPNKAPSGSISATKNIPMNELRDRINEIPKDKKV
                     YITFRRGLNTYTSARILAGLGIKAILIEE"
     gene            complement(2308..3216)
                     /locus_tag="ACG8LA_002883"
     CDS             complement(2308..3216)
                     /locus_tag="ACG8LA_002883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFQ0205127.1"
                     /translation="MVLLLTNNQSSNLVKKTLTYSIDTHLHLSAAPYFRLLINESANL
                     YAEFAHKSIELDNPSLLFIDKQQEVQIFSTQKETQTFIIIQFYFDEQLLAHITGQSFS
                     IDQEITSIITFLKNEQFKIDYLKHSKPAISYDQEINSFFILCQQMSIHLLSLLVTYCL
                     QKIQLSSLPRHYQQELALLTIPSNEKVIPKKKHILYSDELVDPIIRYLEEHLSENFLL
                     EQLAQIFFISPASLKKHFRKVNGKSVISYFKELKMEKAKRLVLENELTYTEIADILGF
                     HSIHHFSSAFKKYTGLSPSKYYLSLK"
BASE COUNT         1068 a          562 c          576 g         1084 t
ORIGIN      
        1 tgttaaataa ataggaacaa aaaaattaaa ttatttaata cacacattag ggatcattca
       61 ttgaaggatt agaagacaac gaggatggcg aaaaatatga ttacaataga aaagtcgttc
      121 taaaccaatc agttcctagt atcacacaac gcaagccagt cgatttggtg agattagagg
      181 agtgaaagca aactttatta tataagaaaa aatattcgaa agggatgcta gtttaggtac
      241 tagtgctgat agattaatat gatgcctcgt aatattaggc gtagttactc tagagacatc
      301 actatggact atgatttgtc tcagagtcac aacatgtttt tttatgaaaa gaaacagcta
      361 aaataattaa attgcgcaat gtttaaactt tcttaaacta taacctaata aatgtgaaga
      421 aataatgcac aatttcttca catttatctt ctattctata tacataccaa ccaacaaccc
      481 tatatacttt ttcattttta ctcctcaagt aaaaataact cctagaccgc ggctacccac
      541 cgcggtcgtt tttttattct tcaatcaaaa tcgctttgat acccaaacct gccaagattc
      601 gggcagaagt ataagtattc aatcctcttc tgaaagtaat gtaaactttt ttatcttttg
      661 ggatttcatt gattcgatct cgtaactcat tcattggaat attttttgtt gccgagatac
      721 tgccagaagg tgctttatta ggttcacgta tatctaaaaa gaacgcttct ttcaaatcgt
      781 tttcgggtat atcacttgct ttgatcgttt ctacgatatt cgtcatttga ttgattgcga
      841 cataaccagc tatattcaac gggtcacggg tagtagaata cggtggagag taaggcaact
      901 ccaaatcagg caaatcaaag actgtcaagt ttccggtgat tgctacagaa agttctccca
      961 tccgtttatc gacacctttt tctccaaatg cttgtccacc taaaatacga ccgctatctg
     1021 catcaaaaat cagctttaga tttaatcttg tagcttctgg atagaaatag gcatggtcaa
     1081 agggagtgat aaaaacagtt ttataatttg ttatgcctga tgcttttaat tcatgttctg
     1141 tcattcccgc ataacttgct gtatgatcaa agatttttgc gacacctgca ccaatatatc
     1201 cgcgatagcg cataggcgta ccatttaaaa tatctgccag catatgtcct tgacgattgg
     1261 ccgcactgga aagcatactt tggatcggct gaccagtcac tacactagtc gtttcgataa
     1321 tatcgccaat cgcatagatg tccggcagat tggtttgtaa ctggtcatca acaatgatct
     1381 gacctgtatc tgataattgt atgccggttg ctttcaccac ttcattcttc ggagaaacac
     1441 caacagcaaa aattagcata tcagcagaaa ggacggagcc atctgataat actatttctc
     1501 gacctttatc acggatctca gtaactcttg tttctaaatg aacggctaat ccttctttca
     1561 gcaatttgtc ataaactaaa ttagcaattt ctggatcata agggaaagcg acttgtggca
     1621 attgatcgat taaagtcacg tctaagccgc gatgcttgaa attctcagct aattccagac
     1681 ccataacacc tgcaccaaga atgacgacat gttgtggatt tttttcttca aggaacgatt
     1741 tgattcgatc cgcatccgtc acactacgga ggacaaagcc gttttctgct tcaaaaactc
     1801 cgggaatatc cggataatct ggtctagcac cagaagagat gatcaactta tcgtaatctg
     1861 tttttatttc ttcatttgtg gataggtctt taactgttaa tcgcttagta gaaggatcga
     1921 ttgctgttac ttcgtgttta gtaaagacat cgatgttgtt ttttgttttc aatatttctg
     1981 gtgtacgttc gatcagcgag tcacggtcag tgatcacacc tcctaaataa taaggcaaag
     2041 cacaacttgc ataagaaata ttttctccgc gttcatagat aatgatttcg tgcgcttcat
     2101 tcaatcgacg gaaacgagtg gcaaatgaag gaccgccagc tacaccgcca atgacaacaa
     2161 ctttcataaa aacatctcct tttctacgtt gatcgtacta tgttatggta aaaaacagca
     2221 aataattgtg ccggaaaatt attgtttatt ttgaatagac agaaaatata gagaaataat
     2281 ttgtggataa aacctaaaaa tttttttcta ttttaaggat agataatact ttgaagggga
     2341 taaccctgta tattttttaa aagctgaaga aaaatgatgg atcgaatgaa atcctaatat
     2401 atctgcaatt tctgtatagg ttaattcatt ttctagcacg agacgttttg ctttttccat
     2461 ttttagttct ttaaaatagc taataacact ttttccattc acttttctaa aatgtttttt
     2521 taagctggct ggactgataa aaaaaatttg ggctaattgt tcaagcaaaa aattttctga
     2581 aagatgttct tctaaatatc gtatgattgg atcaactaat tcatctgaat aaagaatatg
     2641 ctttttttta ggaatgactt tctcatttga aggtattgtc aataaagcaa gttcctgttg
     2701 ataatgcctt ggtaaggaag acaattgaat tttttgcaga caataagtaa ctaataagga
     2761 aagcaaatga atgctcatct gttggcatag tatgaaaaaa gaattgattt cctgatcata
     2821 ggaaatagct ggcttactat gttttagata atcaattttg aactgttcat ttttcagaaa
     2881 agtaatgata gatgttattt cttgatctat agaaaaagat tgtcccgtaa tatgtgctaa
     2941 taattgctca tcaaaataaa actggataat gataaaagtt tgtgtttcct tttgagtaga
     3001 aaagatttgg acttcttgct gtttatcaat gaataaaagg gaaggattat ctagttctat
     3061 agatttatgt gcaaattcag catataaatt agcgctttca tttattagta gtcgaaaata
     3121 gggagcagca gataaatgaa gatgggtatc tatggaatag gttagtgttt ttttgacaag
     3181 attggaggat tggttgtttg ttaacaaaag aaccactttc ctttctcttt ttatataaaa
     3241 agctttctat ttataattaa tgactattat aacaaaaatg aaaagccaaa
//
LOCUS       DAZKKZ010000138         3221 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.147, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000138 DAZKKZ010000000
VERSION     DAZKKZ010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3221)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3221)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3221
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.147"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            301..585
                     /locus_tag="ACG8LA_002884"
     CDS             301..585
                     /locus_tag="ACG8LA_002884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0205128.1"
                     /translation="MDILVRNIDPKFVATIDKRCQELTNKTGEKWSRNKYLKVLIESD
                     FDRQLTTYKKDQFDLLLDKFIAIQTENTQILSEYVYTNNQIIEMLIGGMI"
     gene            588..1004
                     /locus_tag="ACG8LA_002885"
     CDS             588..1004
                     /locus_tag="ACG8LA_002885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0205129.1"
                     /translation="MRKTSVQKHVTLYPSHVDVLDSIIEKNPDINNYSEAIRFLCMSY
                     EPDTNTTTTSNQAKLNAMGKEISIMTEIIAEFADLYLKDTGVLIGTNSKVYQEVKEKI
                     EAKLNPSNRNRPKNHQKETSQTVTSRNFDPTNFLKR"
     gene            complement(1141..1860)
                     /locus_tag="ACG8LA_002886"
     CDS             complement(1141..1860)
                     /locus_tag="ACG8LA_002886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HFQ0205130.1"
                     /translation="MDEKTELTVKYQNELNLVPLKNFNAKQMDLFFALCARMKDRGLK
                     KVRFSFEELKELSDYKMTATKAFVGDLEKLYKDMLNLTYRTEDEDSIRYFVLFTGFEI
                     NKTKKFVEVSVNPDLEYIINGLTAEFSRFELSAFTSLRSTYAKTLFRLLMQYRSTGYY
                     VVRIEEFRSLMDIPEYYQMGNIDQKVLNPALRELKKYFNDLKVTKIKAKKGNKIAKLE
                     FTFSSLTSDLPKISLRNWLEE"
     gene            2544..2630
                     /locus_tag="ACG8LA_002887"
     CDS             2544..2630
                     /locus_tag="ACG8LA_002887"
                     /inference="COORDINATES: protein motif:HMM:NF033608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HFQ0205131.1"
                     /translation="MFTNFICSLLVGLLSALFSYWLNNRNKK"
     gene            complement(2932..>3221)
                     /locus_tag="ACG8LA_002888"
     CDS             complement(2932..>3221)
                     /locus_tag="ACG8LA_002888"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0205132.1"
                     /translation="EYRRQRSDFISRKIVRLEKEKMEKFPYEYFQNLEKLEQAIQAIK
                     FDLTDEKLLEYKNMTPERKRSLEKLMQLVNEDGGISDAAFDAWSEFHGEYN"
BASE COUNT         1074 a          599 c          503 g         1045 t
ORIGIN      
        1 aaaaaaaatg tcgtttgaaa aactaaataa atttttgatc gtgcattttt aaatttggtt
       61 atcgattaca cgtgcagcac tcccccccga attttaaaga gcataaggaa acgtgtaccc
      121 actttctaaa aaaagtgggt agataggctg tgcctatcac gtttctcaga aaaaaatttg
      181 atatcacttt ttcgccatcg tgggtagctt atgtatagca ttttggcaaa aaacagctat
      241 acaaatatag tatttgtatg gtatacataa attatacata attgcaaaag gagatttttt
      301 atggacattt tagttcggaa tattgatcca aagtttgttg caacaataga caaacgttgc
      361 caagaactca cgaataaaac aggagaaaaa tggagtcgaa ataaatatct aaaagtttta
      421 atcgaaagtg attttgaccg tcaacttacg acttacaaaa aagaccaatt cgatttattg
      481 ctcgataaat ttattgctat ccaaacagaa aatactcaaa tattaagcga gtatgtctac
      541 acaaataatc aaatcattga aatgcttatc ggaggaatga tataaccatg agaaaaactt
      601 ctgtccaaaa acatgttact ttgtacccta gtcatgttga cgttttagat tccatcatcg
      661 aaaaaaatcc agatatcaat aactactcgg aagccattcg ctttttatgt atgagttatg
      721 aacccgatac caacacgacc actaccagca atcaggcaaa actaaatgct atgggaaaag
      781 aaatttccat catgactgaa atcatcgcag aatttgctga tttatatcta aaagatacag
      841 gcgttcttat tggcacaaat tctaaagtat atcaagaagt gaaagaaaaa atcgaagcta
      901 aactaaatcc atcaaatcga aatcgaccaa agaatcatca aaaagaaacc agtcaaacag
      961 tcacttctag aaatttcgac ccaacaaatt ttctaaaacg ataaaaaaca gataggagtt
     1021 attcctatct gttttttatt tagaagcccc atacaatatg ctagaatgta ctagcaatct
     1081 tagtcggttg taagggactt gtctacttgc ttaatgtaag gggggcgagt tcttttttat
     1141 ttattcttct aaccagttac gcagagaaat ctttggcaaa tctgacgtta ggcttgaaaa
     1201 agtaaattct aatttggcga ttttattgcc cttttttgct tttatttttg tgactttaag
     1261 atcattgaag tattttttta gttctcgtaa tgcaggattt aatacttttt gatcaatgtt
     1321 acccatttga tagtattctg ggatatccat taagctccta aactcttcaa tacgaactac
     1381 ataataacca gtagaacggt actgcataag cagtcggaat agagtttttg catacgtaga
     1441 acgcaacgac gtgaaagcag ataattcaaa tctactaaat tcagctgtta aaccattaat
     1501 aatatattct aggtccggat taacactgac ttcaacaaac ttttttgttt tattgatttc
     1561 aaaaccagta aacaaaacaa agtagcgaat agaatcctca tcttcagtac ggtaagtaag
     1621 attaagcata tctttataga gcttttctaa atcaccgaca aaggcttttg tagcagtcat
     1681 cttataatca cttaactctt ttaattcctc gaaagaaaat ctaacttttt tcaaaccacg
     1741 atctttcata cgagcgcata atgcaaaaaa taaatccatc tgcttagcat tgaaattttt
     1801 cagcggtact aaattcaatt cattttgata tttgactgtt aattccgttt tttcatccat
     1861 tcctttcttc cccccttaca aataaataat aacctttaac aaccaactcg taaataggtt
     1921 ggttgttatt atacaaaagg atattagtac tcagataaaa agttgttagt actcagataa
     1981 aaagttgtta gtactcagat aaaaagttgt tagtactcag ataaaaagtt gttagtactc
     2041 agataaaaag ttgttagtac ccttctgtat ccgttgggag agtaaggctc aactgccccc
     2101 taaaaagggt tctaaaaaat ctttaaaaaa taaataaaat aaacgcgcgc gcgcgagcaa
     2161 aatttcccgc caaaaaatca cccacttttt aaaataaaca ggttcgcgca tgatattaaa
     2221 ctgccaatct agctccctat ggtcgctgta agaaggagtg atcgctacgc tctcacattt
     2281 tacttgcagc agtcgccttt aggctccttc gccaaaaata attcattagg gactcctttg
     2341 tggcgtcctg agagctcgtc taagccgttc taagacaaga ttcgataaaa actatgtcct
     2401 tcgttctaaa gcgccttaca ggcggtcagg gcaagcccta acaaccccaa ggcaataaaa
     2461 aacttaggct tatttttgct tttttattgt ataattgatt gtcgcctatc cgacagtctt
     2521 gcgactggaa ggaggtgtgt ttcgtgttca ctaactttat ttgctccctt cttgttgggc
     2581 ttttaagcgc tttgttcagt tactggttga ataaccgaaa caagaagtaa aacttaatta
     2641 aggcgactca gcccacaaaa aaagccccag agaatccgac ctctctgggg ctttcgtgtg
     2701 tttcgtgttc acttatttgc aatcaaatta taacagaaat aaatatttat ttcaaaaata
     2761 tcctacaaaa gtctaaaatc cgtaattatt tcttatatgc aacatttaca aataaagtcg
     2821 ctctgagagc tcgtattttt cgatttaaga cgttttattt agtttttggt gtatttcatt
     2881 ggtccaagct aaaaaactct tagaagcgat tttagagcca tttaaaccca cttaattata
     2941 ttctccatga aattcgctcc atgcgtcaaa agctgcgtct gaaattccgc cgtcttcgtt
     3001 cactagttgc attaattttt ccaacgatcg ttttctttcg ggtgtcatat ttttatattc
     3061 caacaatttt tcgtctgtta aatcgaactt gattgcttga attgcttgct ctaatttttc
     3121 taagttttga aaatattcgt aaggaaattt ttccattttt tctttctcca gtctcacaat
     3181 ttttctagaa ataaaatcac ttctttgccg tctatactct c
//
LOCUS       DAZKKZ010000139         3209 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.148, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000139 DAZKKZ010000000
VERSION     DAZKKZ010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3209)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3209)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3209
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.148"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(429..1043)
                     /locus_tag="ACG8LA_002889"
     CDS             complement(429..1043)
                     /locus_tag="ACG8LA_002889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HFQ0205133.1"
                     /translation="MSLCYFDYYHQLEEKLRIEEPLMLQAGTWIAKQINQGGRLQIYA
                     SRTLSGVAFEFWDQTPDLVPSILIENPAGGVYETLEGAGQAIIDQLSVKSEDIFLLLS
                     NEGRNPAIIELAQWIKENGHPLIIVTGFDLSRSIKSQHSSGLRLFEFADLVLDNHANL
                     HDAVLTLPNLDPAICGTASLATIFLLQQVLYFTAKQLVQDTSGK"
     gene            complement(1649..2026)
                     /locus_tag="ACG8LA_002890"
     CDS             complement(1649..2026)
                     /locus_tag="ACG8LA_002890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0205134.1"
                     /translation="MGKLVAVAQSLLDILKWLMEGSNWIFVLPLLLISLFIMFRMVRK
                     KETFLIFIWYAASVGVATLMVELALGSWEACVFALFFAVLYLIIYIPYMKRKSRIGRK
                     GRHTTTFSSTDSLEQSRRTRRRR"
     gene            complement(2326..3207)
                     /gene="galU"
                     /locus_tag="ACG8LA_002891"
     CDS             complement(2326..3207)
                     /gene="galU"
                     /locus_tag="ACG8LA_002891"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003983 - UTP:glucose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0006011 - UDP-glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HFQ0205135.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LDSGIEDILIVTGKEKRPIEDHFDANIELENNLREKEKTELLALVEETTQVNLHFIRQ
                     SHPRGLGDAVLQAKAFIGNEPFVVMLGDDLMKDDIPLTQQLMMDYEETQASAVAVMRV
                     PENETSKYGIIDPKTDSEKGRCRVKGFVEKPEMGKAPSNLAIIGRYLLTPKIFEILET
                     QEPGAGNEIQLTDALQTLNQTEAVYAREFKGKRYDVGDKLGYMKTNIEYGLQHSEIGT
                     SLSAYIIQLSKKLRTES"
BASE COUNT          977 a          658 c          496 g         1078 t
ORIGIN      
        1 ttatttctat tagaaaaagg tatcctgttg gacaattttg ttatatcagg taaacttcat
       61 tgcaataatg ataacaaatg tactataatt actttgtaaa gagttttggg gaagactctt
      121 tcatcaacgt gtattaagag acaagaaaga atccatatgg attctttctt gtctcttttt
      181 ccactacttt ttatttttct gacactacat attcttataa ctcatttctc ataactgtga
      241 aacaacttat aaaaataaca aactttaaac aaaacaagct taaaatcaaa gatgatccat
      301 cttaaaataa ctaaaacaaa aaaagtagtc gttgttaatc ctcattaata atcgttttct
      361 ttttttcaaa cgctccattt ttatgtggaa cattattttt ttaaggaact ttgtcaacat
      421 gtggataact attttccact tgtgtcctgg actagctgtt ttgctgtaaa atacaaaact
      481 tgctgcagca aaaagatcgt tgcaagagag gctgttccgc agatcgctgg atctagattt
      541 ggcaaagtca agactgcatc atgtaaattg gcgtggttgt ccaaaaccaa atcagcaaat
      601 tcaaataatc gcaaaccact gctatgttgc gatttgatac ttcgtgacaa atcaaatcca
      661 gtaacaatga ttaatggatg accattttct ttgatccact gagctagttc gatgattgcc
      721 gggtttcttc cttcattcga aagaagaaga aaaatgtctt ctgatttgac agaaagctga
      781 tcaataattg cctgtcctgc accttctagc gtttcataga cacctccggc tggattttca
      841 atcaatatac ttggtacaag atccggggtt tgatcccaaa attcaaatgc tacaccactt
      901 agtgtgcggc tagcatatat ctgcaatcta ccaccttgat taatttgttt cgcgatccaa
      961 gtgccagctt gaagcatcag cggctcttct atccttaatt tctcttccaa ttggtgataa
     1021 tagtcaaaat aacataaact catttatctc tcccgcctag ctatacttga catgaataga
     1081 aacagctgcc taatctaagg aagtacataa aaaaacagta gttagacagt aacacatgtg
     1141 gtctttgctg tttcaaacac aaaaaaggca ttgaacgaat acgcccaata ccttgacata
     1201 gcaaataaaa caacgtgcag accatggaaa atatctacat aggggtagaa ttttcaccct
     1261 agattaggta caataaatta ggtcgatgca ctgcattgac tatggcaaaa tgatcggtca
     1321 gggtgtatgt gtgtgactgg tcattccctg attcttagcg ccaactaagg gtcagggagc
     1381 ctttttttat tcagctgttt ctatctgaat ttattgtaag taatctctta tccaagtgca
     1441 agcaagaaaa tacaaaaaaa cattggtatg atttatatat atataaataa cataaaaaaa
     1501 ggaatggctt atcccgatac aacaagcatt cctttaaaaa agattctttt atataagtga
     1561 aaaaagcttt tttccaccaa ttaaataaat ctctcatctc aatagtttat ccattatttt
     1621 atcttttttt gcgtatacct actaaatatt accgtcttct tctcgttctt ctactttgtt
     1681 cgagagaatc tgtactagaa aaagtagttg tatgtctacc ttttctgcct atccgagact
     1741 ttcttttcat atatgggata taaatgatta gatacagtac agcaaaaaat aaagcaaata
     1801 cgcaagcttc ccaactacct aacgccaatt caaccatcaa ggtagcaacc ccaacggatg
     1861 ctgcatacca gataaaaatc agaaacgttt ctttttttct gaccatgcga aacatgataa
     1921 atagactaat aagcaatagt ggcaacacaa atatccaatt gcttccttcc atcagccact
     1981 tgagtatatc aagcagcgac tgtgcaacag cgactaattt tcccatagtg aacacacacc
     2041 tttttttata attaaaaaat tcgctttttt attctactat gaatcttctg gcttggcttt
     2101 catttctctt atgtaatcat tttcttttat acaacttaaa aaaaaattaa accattagca
     2161 taatattttc tgaatctatt cacgaaagtc tttttctatc tttcgttttc cacgactcaa
     2221 ctgatctaga gtcaaaaaac taaaacgaca gttgcgcaaa tgacgcacaa gctgccgctt
     2281 taataacaaa tagcctttca ttctcagcag gccacttatt tccagttaac tttctgttct
     2341 tagcttttta ctcaactgga taatatatgc acttaatgaa gtcccaattt ccgaatgttg
     2401 aagtccatat tcaatatttg tcttcatata tcctaactta tcgcctacgt cgtatctttt
     2461 tcctttaaac tctctcgcat agaccgcctc tgtctggtta agagtctgaa gtgcatccgt
     2521 tagctgtatc tcgtttcctg ctcctggttc ttgagtttct aatatctcaa atattttagg
     2581 agtcagtaga taacgtccga taatggctaa attacttggt gcttttccca tttcaggttt
     2641 ttctacaaac ccttttactc tgcaacgacc cttttcgcta tctgttttag gatcaataat
     2701 tccgtattta gatgtttcat tttctggtac acgcatgacg gcaacagcgg aagcttgtgt
     2761 ttcttcataa tccatcatca attgttgagt caatgggata tcatctttca tcaaatcatc
     2821 ccccagcatg acgacaaacg gttcatttcc tataaatgct tttgcttgaa gcacggcatc
     2881 ccccagtcct cttggatgag attgacggat gaagtgaaga ttgacttgag tcgtttcttc
     2941 aactaaagcg agtaattctg ttttttcctt ttcccgcaaa ttgttttcca attcgatatt
     3001 tgcatcaaag tgatcttcaa tgggtctttt ttcttttccc gttacgatca agatgtcttc
     3061 gattcccgaa tccaatgctt cttccacaat aaactggatc gttggtttat ccacgattgg
     3121 aagcatttct tttgccatgg cttttgttgc cggcaaaaaa cgtgttccta gcccagcggc
     3181 aggaatgact gcttttttga ccttcactt
//
LOCUS       DAZKKZ010000140         3201 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.149, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000140 DAZKKZ010000000
VERSION     DAZKKZ010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3201)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3201)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3201
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.149"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..209)
                     /locus_tag="ACG8LA_002892"
     CDS             complement(<1..209)
                     /locus_tag="ACG8LA_002892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFQ0205136.1"
                     /translation="MKIGYARVSTGLQNLDLQEDSLNKFGCEKIFTDHMSGAKSNRPG
                     LEMAIDFVRSGDTLVVWRLDRLGRN"
     gene            complement(583..849)
                     /locus_tag="ACG8LA_002893"
     CDS             complement(583..849)
                     /locus_tag="ACG8LA_002893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HFQ0205137.1"
                     /translation="MKSNKSFNKVLELTETALATPEIKKDKNLCEILEKVKASAAKGE
                     FYYDYKKEFQPAISGFTIRNGFSTPKVLLELLAEVKTPKAWSGL"
     gene            complement(854..1069)
                     /locus_tag="ACG8LA_002894"
     CDS             complement(854..1069)
                     /locus_tag="ACG8LA_002894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II bacteriocin"
                     /protein_id="HFQ0205138.1"
                     /translation="MRKKLFSLALIGIFGLVVTNFGTKVDAATRSYGNGVYCNNSKCW
                     VNWGEAKENIAGIVISGWASGLAGMGH"
     gene            1600..2211
                     /locus_tag="ACG8LA_002895"
     CDS             1600..2211
                     /locus_tag="ACG8LA_002895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFQ0205139.1"
                     /translation="MAKIGYARVSSIDQNLDRQLELLSKCDKIFTDKASGKDTNREGF
                     QKMMEFIREGDIVVVTELKRLGRNNKELTETMNLIQLKKATLEVLNLPALTGITDDNL
                     RRLLNNLIIELYKYQAEEERRYIRETQQQGIALAKAKGKYKGGKPKYREDDKRLQLAF
                     KLFLAGSTDKEVEEQTGINRRTFRRYRMKYGITSKLREKNKIK"
     gene            2312..>3201
                     /locus_tag="ACG8LA_002896"
     CDS             2312..>3201
                     /locus_tag="ACG8LA_002896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0205140.1"
                     /translation="MEFINNTKEKILNSPYFNKVSYLFEESFMTYSIGAYRSSYITSY
                     VGFLQQIRQNIINYNENPYFSIIEKKENETEEKYKAKIENKWRGLNKNLIDVDKWENA
                     LISALNENTDTNILRLNDGDRTKLLYFKNIRNDAVHDKTNQITLAQLQSLWEFIIEYA
                     HRTRIGENKESFLKNYQEITEWYKQSGDIPENRLRVIEESFYLLTEKEKIEILSIFYR
                     SFFNPRPDDIYTLHTEEVFNHLFENHRLEMYNLLSSDPELALFSIFVINNIDVACLQW
                     NRDRSDSILRLDNRMIDKII"
BASE COUNT         1202 a          469 c          494 g         1036 t
ORIGIN      
        1 atatttctac ctaaacgatc taagcgccaa acgacgagtg tatcgccaga gcgaacaaaa
       61 tcaatagcca tttctaatcc tggtcgatta ctttttgccc cactcatatg atcagtaaaa
      121 attttttcac aaccaaattt atttaggctg tcttcttgta aatccaaatt ttgtaaacca
      181 gtagatactc gggcgtatcc tattttcaaa aaaaatcact ccttcattaa ttttattgta
      241 acataacttt ataccaacga tataaatgaa catagatttt gtgatgggtt tgtgaacact
      301 aaaagtatag aaaaatttaa atttaaggta aaaaaatgta gtgtccagaa atgcctgatt
      361 ttatgaacac tttgttcaac agtaactttt gctaatcata caagatccga agattatact
      421 cgctcatttt tccataaaaa agaagccgtt cttttgacga acgacctctc ttttgatttg
      481 tactatccaa atatattgta acattttaat ttctatattc catatgttcc ttaaaactca
      541 attagatact cttacaaaaa atagaatagc acttatcata actcaaagtc ccgaccatgc
      601 tttgggagtt tttacttcag caagcaactc caataaaacc ttcggtgtgg aaaagccgtt
      661 tctaatagtg aatccactaa ttgcaggttg aaattctttc ttgtaatcat aataaaattc
      721 acctttagca gcactagctt ttactttttc taaaatttca catagatttt tatctttttt
      781 aatttctggg gtggctaatg ctgtttcagt taattctaga actttgttga aagatttatt
      841 acttttcata gtattaatgt cccatacctg ccaaaccaga agcccagcca ctaataacga
      901 ttcctgcaat attctcttta gcttctcccc agttaaccca gcatttacta ttattacaat
      961 aaacaccatt accatatgaa cgcgtagctg catcaacttt tgtaccaaaa tttgtcacaa
     1021 ctaacccaaa tattccaata agagctaaac taaataattt ttttctcata aatcaatacc
     1081 tcctttttct aaaataatta taaatgattt ttagaaaaat ttgataatta tatcataaac
     1141 agttgttttg aaagcataat ggcaataaaa aatcattgtt aaaactaatc tcatttgtat
     1201 tcttcgggga attaattcat tccctagaaa atcgtgtgtc acacaataac gcgcataatt
     1261 tcctactttt ctcaaatatt ttgctacttg attttcatat tcttccattt ctggagtata
     1321 ccctattgag atctaatttt atatctatct gaacttaatt aagtgaacta ttgaaagaac
     1381 gctgaaatga gaaattaaaa caggatcaaa accttaaaag ttgttggccc ttctataaag
     1441 ctatagaata tttttcgaat ttttgtgtga caaatactga gaaaaatttt tgccatttaa
     1501 atataaaaat gacacttgga tttctaaggg gtcaacagag ttgggcaaca ggattttaaa
     1561 aatgatccaa atttttgaat tttaaaggag tttttttcta tggctaaaat tggatatgct
     1621 cgagtaagca gtattgatca aaatttagat agacagctag aattgttatc aaagtgtgat
     1681 aaaattttta ctgataaggc aagcgggaaa gataccaatc gtgaaggatt tcaaaaaatg
     1741 atggaattca tacgtgaagg tgatattgtc gttgtgacag aattaaaacg tcttgggcga
     1801 aataataaag agctaacaga aacgatgaat ttgattcagc tgaagaaagc gactctggaa
     1861 gttttgaatt taccagcgtt aacagggata actgatgata atttgcgtcg attacttaat
     1921 aacttaatta ttgaactata caagtaccag gcggaagaag aacgtcgata tattcgtgaa
     1981 acgcagcaac aaggtattgc gcttgctaaa gcaaaaggaa aatataaagg tgggaagcca
     2041 aagtatagag aagatgataa acgtctgcaa ttagcattta aattattttt agctggatct
     2101 acagataaag aagtagaaga gcaaacagga attaatcgaa gaacatttag aaggtacaga
     2161 atgaaatacg gaatcactag taaattgaga gagaaaaata agataaaata acttaaaaat
     2221 tcacagagat tgaaccgatt tcatattttt acttgagtct taattaacaa atataatcca
     2281 ttaatttaaa aattaagtaa ggatggagta aatggaattt ataaacaata ctaaagaaaa
     2341 aattttgaat agtccctact ttaataaggt gtcttattta tttgaagagt cttttatgac
     2401 ctattcaata ggagcgtata gatcatcgta cattacttcg tatgtaggct ttttacaaca
     2461 aataagacaa aatataataa attataatga aaatccttat ttcagtataa tagaaaagaa
     2521 agaaaatgag acagaagaaa aatataaagc aaagattgaa aacaagtgga gagggttaaa
     2581 caaaaatcta atcgatgttg ataaatggga aaatgctctt attagtgctt taaatgaaaa
     2641 taccgatact aatatattaa ggctgaacga tggggataga actaagcttt tatactttaa
     2701 aaatattaga aatgatgcag tgcatgataa aacaaatcaa atcactttag cacaattgca
     2761 atctttatgg gaattcataa tagaatatgc acataggact agaataggcg aaaacaagga
     2821 aagcttttta aaaaattacc aagaaattac cgaatggtat aagcaatctg gggatattcc
     2881 tgaaaataga ttaagagtaa tcgaagagtc tttttattta ttaacagaaa aagaaaagat
     2941 agaaattctt agtatttttt atagaagttt ttttaatcct cgtcccgatg atatttacac
     3001 tctgcatact gaagaagtat ttaatcactt atttgagaat catcgactag aaatgtataa
     3061 tctgcttagt tctgatcctg aattagcttt attttctatt tttgtaatta ataacataga
     3121 tgtagcatgt ttgcaatgga acagagatag aagtgattca atattacgac tagataatcg
     3181 gatgattgat aaaataatta g
//
LOCUS       DAZKKZ010000141         3197 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.150, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000141 DAZKKZ010000000
VERSION     DAZKKZ010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3197)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3197)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3197
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.150"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..144
                     /locus_tag="ACG8LA_002897"
     CDS             <1..144
                     /locus_tag="ACG8LA_002897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018579902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0205141.1"
                     /translation="QTPQNFNKKLQRETVTLDELKAIADVLGVKFVQAFILPDGNEIK
                     IGN"
     gene            160..1002
                     /locus_tag="ACG8LA_002898"
     CDS             160..1002
                     /locus_tag="ACG8LA_002898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0205142.1"
                     /translation="MKIITINDVEYAVFAANEGTSKPQPHIIETKSGTIPEGKQLSLL
                     KEYLKQNDISPIKGATTYWCIDKVLKLDSSKEKTISETIHKQKYLSLTEENIEKQHKF
                     VGASSNYGKEGLIIHDVLNAFPLHNDLNTIAMKIAVIDVTNSTHLSQYKSRLSLYDLA
                     KVILEIPNFDDRLAKGDPQLINIIARNIGAVNMFSFASKYCTYHNVEVCGRDDYSIFD
                     GIVKNTLPHYIQGLTTNKIDTWRRSFDYEAFNECVGKLLDENNIHIPFRRRKLDHFLW
                     YANR"
     gene            1065..2867
                     /locus_tag="ACG8LA_002899"
     CDS             1065..2867
                     /locus_tag="ACG8LA_002899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004527 - exonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease domain-containing protein"
                     /protein_id="HFQ0205143.1"
                     /translation="MGLFDFLKKKQGKVSKHVDYQLASSLFRTGKVFAEKLEVDISNV
                     DEFRKTFIAFDVETTGLNSSSDRIVEIGAVLFKEGVPIQSFGTLVNPKVRIAASASAI
                     NNITNEMLNSAPNEQEVYPQLVEFLGDALDGKITMCAHNASFDFGFLSNTFSRLGYDA
                     KIKYVDTLSLSRKHIKGIVNHKQETVAEYFGLINDTAHRAESDADICGKIFWGVLDII
                     EESLEEQKKQIEKMTPDIKELEACAFIQDIIEKKGCDTSWIRYRKNSNNYVDVTCLYT
                     FLKFKFAKKGNYIIIRKDATNGIDLPIEPCTVSEGGTTNVRVYFRSPFDLTPLSNYIF
                     SAYSDCYNSMNEYMSVSNYTKKEAEQSLSMLKSISKSAMKELLFDAKNRGYDETEVNL
                     NIEKVISREDVIINGLHNRVSLNKIRNIGNWEKGFDAGYPYWERGETARKNGKVDEAI
                     ALFDKARYNGYDAPALYDSYAKAYRKIKDYDNEILILDEGIMRKTRHDVGTLEARRDK
                     AIKLLFAKQEAERIAKEKSDFLKANKKEDAISEPSKKRGRQIIQMTDDGTIIKEFDTI
                     ASAVKEVGVNSKSIRDAANGVQKHAGGYCWKYKD"
     gene            complement(2926..>3197)
                     /locus_tag="ACG8LA_002900"
     CDS             complement(2926..>3197)
                     /locus_tag="ACG8LA_002900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFQ0205144.1"
                     /translation="LALKGITISVPPRKNMDKSEKLDHSLLGKQRKTVETVFSSLEKL
                     GCQNFNSRSVKGLESRFESILLAYSVLLSRAQRRFEGTLRYSLGY"
BASE COUNT         1148 a          442 c          648 g          959 t
ORIGIN      
        1 cagactccac agaatttcaa taagaaatta caacgagaaa cggtaacctt agatgagttg
       61 aaagcgattg ctgatgtgct aggtgtcaag tttgtgcagg cttttatatt gcctgatggc
      121 aatgaaataa agataggtaa ttaggaggtg taatttgtat tgaaaatcat aacaataaat
      181 gatgttgagt atgctgtatt tgctgctaat gaaggtactt ccaaaccaca acctcatatc
      241 atagaaacga aatctggtac tattccagaa ggaaaacaac tgagtttatt aaaagaatat
      301 cttaagcaga atgatatttc cccaataaaa ggagcaacaa catattggtg cattgacaag
      361 gttcttaagc ttgattcaag taaagaaaaa actataagtg aaacaatcca taaacaaaaa
      421 tacttatctt taactgaaga aaatattgag aaacagcata agtttgtagg tgcaagctct
      481 aattatggga aagaaggtct aataatacat gatgttttga atgcatttcc tcttcataat
      541 gatttaaata ctattgcgat gaagattgcg gtaattgatg taacaaattc aacacatctt
      601 tctcaatata agagcaggtt gtctttatat gatttggcta aagtaattct ggagattcca
      661 aattttgatg atcggttggc aaaaggagat cctcagttga taaatattat cgcaaggaac
      721 attggtgcag ttaatatgtt ctcatttgca tccaagtact gtacatatca taatgtggaa
      781 gtgtgtggga gagatgatta ctccatcttt gatggtatcg ttaaaaatac tcttccacac
      841 tatatccaag gactaactac gaataagatt gatacgtggc gaagaagttt tgattacgag
      901 gcatttaacg aatgtgttgg aaaactacta gatgaaaata atatacatat tccttttaga
      961 agaagaaagt tagatcactt cttgtggtat gcgaataggt agaatataag aaaaagacat
     1021 cgtaaaagtg attatggata aaattaatgg gggaggaaat aatagtggga ttatttgatt
     1081 ttctaaagaa aaaacaagga aaggttagta aacacgttga ttatcaactg gcttctagtc
     1141 tatttcgtac tggtaaagtt tttgctgaaa aattggaagt ggacatatca aatgtagatg
     1201 agtttcgtaa aacttttatc gcttttgatg tggaaacaac tggcctaaat tcttcttcag
     1261 atagaattgt agagattggt gcggtgctat ttaaagaagg agttccaatt caatcattcg
     1321 gaactcttgt caatccaaaa gttagaattg cagcctcagc ttcggcaata aataatataa
     1381 ctaatgaaat gctaaactct gctccaaatg agcaggaagt ttacccccag ttggtagaat
     1441 ttttaggaga tgcactagat ggaaaaatca ctatgtgtgc acacaatgca agtttcgatt
     1501 ttggattttt aagtaacaca ttttctagac ttgggtatga tgctaaaatt aagtatgttg
     1561 atactctgag tctctctaga aaacatataa aaggcattgt aaatcataag caagagactg
     1621 tagcggaata tttcggatta ataaatgaca ctgcccatag agcggaatca gatgcagata
     1681 tatgcggaaa gattttttgg ggtgttttag atattattga ggagtcgttg gaagaacaaa
     1741 aaaagcaaat agaaaagatg actccagaca taaaagaact tgaagcttgt gcttttattc
     1801 aagatattat tgagaaaaaa ggatgcgaca ccagttggat caggtatcga aaaaacagta
     1861 ataattatgt cgatgtaact tgtctatata cattcttaaa gtttaagttt gctaagaagg
     1921 gaaattacat cattattaga aaagatgcta caaatggaat tgatttacct atagaacctt
     1981 gtactgtaag tgaaggcggt acaacaaatg tgcgagtcta ttttcgtagc ccctttgact
     2041 taacgcctct ttcaaattat attttcagtg cttatagcga ttgttataat tctatgaatg
     2101 aatatatgag tgttagtaat tacactaaaa aagaagcaga gcaaagcctt agtatgctga
     2161 aatctatttc aaaatcagcg atgaaagagt tattattcga tgcaaaaaat cgtggatatg
     2221 atgagactga agttaaccta aatattgaaa aagtgatatc tagagaagat gtaattatta
     2281 acgggttgca taatcgagtt tcattaaaca agatacgaaa tatagggaat tgggagaaag
     2341 gatttgatgc aggttatcca tattgggaac gtggagaaac tgctaggaaa aatggcaaag
     2401 tagatgaagc tattgcactt tttgataaag ctcgatataa cggctatgat gctcctgcgc
     2461 tatatgattc ttatgctaaa gcttatcgaa aaattaagga ttacgataat gaaattctca
     2521 ttcttgatga aggaattatg cgtaaaacac ggcacgatgt tggtacttta gaggctcgta
     2581 gggataaggc aattaagcta ttatttgcta aacaagaggc agagcggata gctaaggaaa
     2641 aatctgattt tctaaaagcg aacaaaaaag aggatgcgat tagtgagcct agcaagaagc
     2701 gtggaagaca gattattcaa atgactgatg atggaacaat aataaaagaa ttcgatacta
     2761 tagcttctgc tgtaaaagaa gttggcgtta actcaaaaag tattagggat gctgcaaatg
     2821 gagttcaaaa acatgctgga ggatactgct ggaaatacaa agattagcag ataatctaag
     2881 ataacctagg atcttcttaa tagatacccg tggtgctagt taattttaat atcctaaaga
     2941 atatctcaaa gttccttcaa aacgtcgttg tgctcgactt aatagaacac tgtaagccag
     3001 taatatgctt tcaaatctac tctctagccc tttaacagaa cgtgagttga aattttgaca
     3061 acctaatttt tctaaggaag aaaaaacagt ctcaactgtt tttctttgtt ttccaagtaa
     3121 gctgtggtct agtttttctg atttatccat gtttttacgt ggcggaacgg atatagtaat
     3181 gcccttaagg gcaagct
//
LOCUS       DAZKKZ010000142         3076 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.151, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000142 DAZKKZ010000000
VERSION     DAZKKZ010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3076)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3076)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3076
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.151"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            468..1640
                     /locus_tag="ACG8LA_002901"
     CDS             468..1640
                     /locus_tag="ACG8LA_002901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS256 family transposase"
                     /protein_id="HFQ0205145.1"
                     /translation="MTQVHFTLKSEEIQSIIEYSVKDDVSKNILTTVFNQLMENQRTE
                     YIQAKEYERTENRQSQRNGYYERSFTTRVGTLELKVPRTRDGHFSPTVFERYQRNEKA
                     LMASMLEMYVSGVSTRKVSKIVEELCGKSVSKSFVSSLTEQLEPMVNEWQNRLLSEKN
                     YPYLMTDVLYIKVREENRVLSKSCHIAIGITKDGDREIIGFMIQSGESEETWTTFFEY
                     LKERGLQGTELVISDAHKGLVSAIRKSFTNVSWQRCQVHFLRNIFTTIPKKNSKSFRE
                     AVKGIFKFTDINLAREAKNRLIHDYIDQPKYSKACASLDDGFEDAFQYTVQGNSHNRL
                     KSTNLIERLNQEVRRREKIIRIFPNQTSANRLIGAVLMDLHDEWIYSSRKYINFDK"
     gene            complement(1770..>3076)
                     /locus_tag="ACG8LA_002902"
                     /note="aph(2'')-Ia"
     CDS             complement(1770..>3076)
                     /locus_tag="ACG8LA_002902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase APH(2'')-Ia"
                     /protein_id="HFQ0205146.1"
                     /translation="LKKHYTEPWEDEVFRVIIEYNNVPIGYGQIYKMYDELYTDYHYP
                     KTDEIVYGMDQFIGEPNYWSKGIGTRYIKLIFEFLKKERNANAVILDPHKNNPRAIRA
                     YQKSGFRIIEDLPEHELHEGKKEDCYLMEYRYDDNATNVKAMKYLIEHYFDNFKVDSI
                     EIIGSGYDSVAYLVNNEYIFKTKFSTNKKKGYAKEKAIYNFLNTNLETNVKIPNIEYS
                     YISDELSILGYKEIKGTFLTPEIYSTMSEEEQNLLKRDIASFLRQMHGLDYTDISECT
                     IDNKQNVLEEYILLRETIYNDLTDIEKDYIESFMERLNATTVFEGKKCLCHNDFSCNH
                     LLLDGNNRLTGIIDFGDSGIIDEYCDFIYLLEDSEEEIGTNFGEDILRMYGNIDIEKA
                     KEYQDIVEEYYPIETIVYGIKNIKQEFIENGRKEIYKRTYKD"
BASE COUNT         1053 a          553 c          399 g         1071 t
ORIGIN      
        1 aaaaagttca aaagatcaag tgtgcgcttc gctcccactc ccctcgacgt tttagtagcc
       61 tttccctcac ttcgttcagt ccaagccaac taaaaagttt tcgggataca ttctccttct
      121 cttcctaata atcaattaaa attttaatct ttatatttct gctaatcact caggaaacag
      181 tacagaaaaa caaacacgta tcatagatat aaatgtaatg gcatagtgcg ggttttattt
      241 tcagcctgta tcatagctaa acaaatcgag ttgtgtgtcc gtttttgggc gttctgctag
      301 cttgtttaaa gtctcttgaa tgaatgtatg ttctaagtca aaaaactctg acagcgcctt
      361 tatatagata aagtccgtat aattgtgtaa aagtaaaaag gccatataac agtcctttta
      421 cggtacaatg tttttaacga caaaaacata cccaggagga cttttacatg acccaagtac
      481 attttacact gaaaagcgaa gagattcaaa gcattattga atattctgta aaggatgacg
      541 tttctaaaaa tattttaaca acggtattta atcaactaat ggaaaatcaa cgaacagaat
      601 atattcaagc aaaagaatat gaacgaacag aaaaccgaca aagtcaacga aatggctatt
      661 atgagcgcag ctttacgaca cgtgtaggca cgctagaatt aaaagtaccc agaacacgtg
      721 atggccattt ttcacccaca gtgtttgaac gttatcaacg aaacgaaaaa gccctcatgg
      781 cttcaatgtt ggaaatgtat gtatcaggcg tttcaactcg taaagtatca aaaattgtgg
      841 aagaactttg tggtaaatcc gtctctaagt ccttcgtttc tagcttaaca gaacagctag
      901 aacctatggt taacgagtgg cagaatcgtt tattatcaga aaaaaattat ccttacttaa
      961 tgaccgatgt actctatata aaagtacgag aagaaaatcg agtactctca aaaagctgtc
     1021 atatagcgat tggaataacc aaagatggcg accgtgaaat tatcggcttc atgattcaaa
     1081 gtggcgaaag cgaagagacc tggacaacat tttttgaata cctaaaagaa cgcggtttac
     1141 aaggtacgga actcgttatt tctgatgcgc acaaaggatt agtctctgcc attagaaaat
     1201 ccttcaccaa cgtaagttgg caaagatgcc aagttcactt cctaagaaat atctttacca
     1261 ccattcctaa aaaaaattca aaatctttca gagaagctgt taaaggaatt tttaagttca
     1321 cagatattaa cttagcgcgt gaggctaaaa atcgattgat tcatgattat atcgatcaac
     1381 caaaatattc aaaagcttgc gcatcattgg atgatggatt cgaagacgcc tttcaatata
     1441 ccgtacaagg aaattcccac aatcgactaa agagtaccaa tctaattgaa cgactgaatc
     1501 aagaagtacg cagaagagaa aagattattc gcatcttccc caatcaaaca tcagccaatc
     1561 gcttaattgg agccgttctt atggacctac atgatgaatg gatttattct tcaagaaaat
     1621 acatcaattt tgataagtag aaatggtaaa aacattgtat agcattttac acaggagtct
     1681 ggacttgact cacttccttt attatttttc atttttttaa actatttaat actaatgtct
     1741 tttataatag cttttcatat attatataat caatctttat aagtcctttt ataaatttct
     1801 tttctaccat tttcgataaa ttcctgttta atatttttaa ttccataaac aatagtttca
     1861 ataggataat attcttcaac tatatcttga tattcttttg ctttctcaat atctatattt
     1921 ccatacattc ttaatatatc ttctccaaaa tttgttccta tttcttcttc actatcttca
     1981 agtaagtata taaaatcaca atattcatct ataattccag aatctccaaa atcaattatt
     2041 ccagttaatc tattattgcc atctaacaat agatgattac aactaaaatc attatggcat
     2101 aaacactttt taccctcaaa aactgttgtt gcatttagtc tttccataaa actttctata
     2161 taatcttttt ctatatcagt taaatcatta taaatagttt cacgcaacaa tatatactct
     2221 tctaatacat tttgtttatt atcaatagta cattcactaa tatctgtata atctaaaccg
     2281 tgcatttgtc ttaaaaaact ggcaatatct cgttttaaca aattttgttc ttcttctgac
     2341 atagtagaat aaatttctgg tgttaaaaaa gttcctttaa tttctttata acctagtata
     2401 gataattcat cactaatata cgaatattca atattaggaa tttttacatt agtttctaaa
     2461 tttgtattta aaaaattata tattgctttt tcttttgcat aacctttttt cttattagta
     2521 ctaaattttg ttttaaaaat gtattcatta ttaactaaat atgccacact atcataacca
     2581 ctaccgatta tttcaatact atctactttg aaattatcaa agtaatgctc aattaaatat
     2641 ttcattgcct taacatttgt ggcattatca tcatatctat attccattaa ataacaatct
     2701 tcttttttgc cctcgtgtaa ttcatgttct ggcaaatctt caataattct aaaaccagat
     2761 ttttggtatg cccttattgc tcttggatta tttttatgag ggtctaaaat aactgcatta
     2821 gcatttcttt cttttttcaa aaattcaaaa atcaatttaa tatatcttgt accaattcct
     2881 ttactccaat aatttggctc tcctataaat tgatccatac catagactat ctcatcagtt
     2941 tttggataat gataatcagt atataactca tcatacattt tatatatttg tccatatcca
     3001 ataggaacat tgttatattc aataattact ctaaaaactt catcttccca aggctctgta
     3061 taatgttttt ttaatg
//
LOCUS       DAZKKZ010000143         2984 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.152, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000143 DAZKKZ010000000
VERSION     DAZKKZ010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2984)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2984)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2984
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.152"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..887
                     /locus_tag="ACG8LA_002903"
     CDS             <1..887
                     /locus_tag="ACG8LA_002903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HFQ0205147.1"
                     /translation="KKVYMYLKKQNEYSLENSKVDSKGRIFLIFAIEKIAEKSCLTKK
                     TVISALRELEEYKLITIKKNGFNKKTGKNNPNFYYLLKPEFSEGDFYKKKCIEENLHL
                     PTNQHYSPSEKNTPSDKSTFDGDKSFPLPGEKFLQELNHSSKDFKDFKESQNADFIDS
                     LSVENKKLDEILIESLIEKEWLYQVWGDNIVNCLKLVGNNDYSQFYDWYKKFKYAIKS
                     AEKEQKIQLKIIYEICNNKYFVDYVREQLSMTLRDLIRRAKTDHRIKQKDDYIFASLK
                     NKALELIELQISEGIDKQ"
     gene            963..1181
                     /locus_tag="ACG8LA_002904"
     CDS             963..1181
                     /locus_tag="ACG8LA_002904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0205148.1"
                     /translation="MIENRLIDQVWCLDQNTDNLELIETICFNTIVLDLRSENDNCVT
                     HIIIDRKTAQKLSESLRKWAEGGNNENS"
     gene            1168..>2984
                     /locus_tag="ACG8LA_002905"
     CDS             1168..>2984
                     /locus_tag="ACG8LA_002905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pLS20_p028 family conjugation system
                     transmembrane protein"
                     /protein_id="HFQ0205149.1"
                     /translation="MKIVKEKIASRKIHWLALSILVLMFIVVFTGNVVQASIFNWFDD
                     TESQTEFLNNPVYQSYLKKYNGNFYSQFGLWIGWSVIKSMFAIVDGIQNMIPEVLDLF
                     SFIESTGMNKVYQSVLSTVVIGLMILSLMFVGYKMITGKGTVDLKSVGMNVVMSVALI
                     LLMPTLIGSTEKLSGIMFAKTLYNDATSINNQDGGVAWSLIEQGVTDLAYINKTDQYS
                     TIDKTNDRNNLTKENFWKTDLTQVLTDNVIDKMEKENPTADNLRYELVENSDNEFVAT
                     KFSDNFLSTFVDGIKSGYYRYQANLWGISFGLIALAVAYVFSAFIIITAILELAFKRV
                     LGVLVFATDLETGQRSKQVLSDILQCYLTVGFQGFGLSMFAMFINYLNTGEGISANIF
                     IKTIAYICAVFVLIKGSGTVMRYFGVDIGLKEGYGQLASAFGMGAMLFRKGTGGMNRS
                     KGGKNNGGNDQAEGEERKPERNFGQSLSKKANKTGKALGYAHERGLSGLASDGSTMAS
                     ERATKPFKSMRDIANDTKSKFKEGLDDGTVSAINKNSKPMLAKNKEDETGKYADSMPT
                     RLSDRKDGAKVENADSIMSSSERMREAMKNNAESNNNPV"
BASE COUNT         1100 a          383 c          583 g          918 t
ORIGIN      
        1 caaaaaaagt ttatatgtat ttgaaaaaac aaaatgaata ttctttagag aattcaaaag
       61 ttgacagcaa aggaagaatt tttttgattt ttgctataga aaaaatagct gaaaaatctt
      121 gtttaacaaa gaaaacggta ataagcgctt tgagagagct agaagaatat aaattaatta
      181 cgattaaaaa aaatggattt aacaaaaaaa ctgggaagaa taatccaaat ttttattatt
      241 tattgaaacc agaattcagc gaaggagatt tctacaaaaa aaagtgcatt gaggaaaatt
      301 tacaccttcc gacaaatcaa cattacagtc caagtgaaaa aaatacacct tccgacaaat
      361 caacattcga tggtgataag tcattcccgc ttccaggtga aaaattttta caagaactta
      421 atcattcttc taaagatttt aaagatttta aagaatctca aaatgctgac tttattgatt
      481 cactttcagt tgaaaataaa aaattagatg aaatattaat tgaatcatta attgaaaaag
      541 aatggcttta tcaggtatgg ggggataata ttgtaaactg tctgaaatta gtgggtaata
      601 acgattacag tcaattttat gactggtata aaaaattcaa atatgcgatt aaatctgctg
      661 aaaaagaaca aaaaattcaa ctgaaaatta tctatgaaat ctgtaataac aagtattttg
      721 tagattatgt tagagaacag ctatcaatga ctttacgtga cttgatacga agagcaaaaa
      781 cagatcaccg tatcaaacaa aaagacgatt atatctttgc ttctctaaaa aataaagcgt
      841 tagaactaat tgaattgcaa atcagtgaag gaatagataa gcaataagaa tagaattgag
      901 tcaaatgaag tggaggggta tctccgcttc atttgagaac tttgaatata ggaggggtta
      961 ttttgattga aaatcgttta atagatcaag tttggtgtct agatcaaaat acagataatc
     1021 tcgaattaat cgagactatt tgcttcaaca ctatagttct cgatttaaga tctgaaaatg
     1081 acaattgtgt aactcatatc ataattgaca gaaaaacagc tcagaagctc tctgagagtc
     1141 tcagaaaatg ggctgaggga ggtaataatg aaaatagtta aagaaaagat tgccagtaga
     1201 aaaatacact ggttagcttt gagcatactt gttttaatgt ttatcgttgt tttcaccggt
     1261 aatgttgtcc aagcaagcat tttcaattgg tttgatgaca cggaaagtca aactgaattt
     1321 ttgaataatc ctgtctatca atcgtattta aaaaaatata acggaaattt ttacagtcag
     1381 tttggattgt ggatagggtg gtctgttata aaatcgatgt ttgcaattgt agatggtatt
     1441 caaaatatga ttcccgaagt gttagatttg tttagcttta ttgaaagtac gggaatgaat
     1501 aaagtttatc aatcggtctt aagtacagtt gttattggtt taatgatact ttcactgatg
     1561 tttgttggtt acaaaatgat tactggaaaa ggaacagtgg atttaaaatc ggttggaatg
     1621 aacgtagtga tgtctgtagc attaattctt ttaatgccga ctttgattgg atcaacagaa
     1681 aaactttcag gaataatgtt tgcaaagact ctttataatg acgcaactag tatcaataat
     1741 caagatggcg gtgtagcatg gtcattgatt gagcagggag tgacagattt agcttatatt
     1801 aataagacag atcaatattc gacaattgat aaaacaaatg accgaaataa tctaacaaaa
     1861 gaaaatttct ggaaaacgga tcttacgcaa gtattgacag ataatgtaat tgataaaatg
     1921 gaaaaagaga acccaacagc tgataatctg cgttatgaat tagttgaaaa ttctgataat
     1981 gaatttgttg ctactaaatt ttcagataat tttttatcaa cctttgttga tggtatcaaa
     2041 tcaggatatt atcgctatca agcgaacctg tggggaattt cttttggatt gattgcttta
     2101 gcggtagcgt atgtttttag tgctttcatt ataattacag caatactcga gttagcattt
     2161 aaacgtgtac tcggagtttt agtatttgct actgacttag aaacaggaca acgatcaaaa
     2221 caagttttgt cagatatttt acagtgctat ttgacagtcg gatttcaagg gttcggttta
     2281 tctatgtttg caatgttcat aaattaccta aatactggcg aaggtatctc agcaaatatt
     2341 tttataaaaa caattgctta tatctgtgct gtgtttgttt taatcaaagg cagtggaaca
     2401 gtcatgagat actttggtgt ggatattgga ctcaaagaag gctatgggca acttgcttct
     2461 gcttttggaa tgggtgcaat gctattccgt aaaggaacag gtggtatgaa ccggtctaaa
     2521 ggtgggaaaa ataatggtgg aaacgatcaa gctgaagggg aagaacgaaa acctgaacgc
     2581 aactttggac aatcactttc taaaaaagct aataaaacgg ggaaagcgct tgggtatgct
     2641 catgaacgtg gattatcagg tttagcttca gatggatcta caatggctag tgaaagagca
     2701 acaaaaccat ttaagagtat gcgtgatata gctaatgata ccaagagtaa gtttaaagaa
     2761 ggtttagatg atggtactgt gtccgctatt aataaaaata gcaaacctat gttagctaaa
     2821 aataaagaag atgaaactgg aaaatatgct gattccatgc caacacgtct ttcggataga
     2881 aaagatggtg ctaaggttga aaatgccgat agtattatgt ctagttctga acgtatgcgt
     2941 gaagcaatga aaaataatgc tgaatcgaat aataatcctg taag
//
LOCUS       DAZKKZ010000144         2932 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.153, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000144 DAZKKZ010000000
VERSION     DAZKKZ010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2932)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2932)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2932
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.153"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            88..984
                     /locus_tag="ACG8LA_002906"
     CDS             88..984
                     /locus_tag="ACG8LA_002906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HFQ0205150.1"
                     /translation="MIQYYYTKKEWGVVMEKEKLKILEELRRILNNKNEAIIILNNYF
                     KGGVGKSKLSTMFAYLTDKLNLKVLMIDKDLQATLTKDLAKTFEVELPRVNFYEGLKN
                     GNLASSIVHLTDNLDLIPGTFDLMLLPKLTRSWTFENESRLLATLLAPLKSDYDLIII
                     DTVPTPSVYTNNAIVASDYVMIPLQAEEESTNNIQNYISYLIDLQEQFNPGLDMIGFV
                     PYLVDTDSATIKSNLEELYKQHKEDNLVFQNIIKRSNKVSTWSKNGITEHKGYDKKVL
                     SMYENVFFEMLERIIQLENEKE"
     gene            1076..1291
                     /locus_tag="ACG8LA_002907"
     CDS             1076..1291
                     /locus_tag="ACG8LA_002907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002401482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
                     /protein_id="HFQ0205151.1"
                     /translation="MIVGNLGAQKAKRNDTPISAKKDIMGDKTVRVRADLHHIIKIET
                     AKNGGNVKEVMDQALEEYIRKYLPDKL"
     gene            1309..1581
                     /locus_tag="ACG8LA_002908"
     CDS             1309..1581
                     /locus_tag="ACG8LA_002908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HFQ0205152.1"
                     /translation="MAVTYEKTFEIEIINELSASVYNRVLNYVLNHELDTKNTRLLEV
                     NLLNQLEVAQEVDLFQQPFEELQAIHEYWRSMNQYSKQILTKEKVA"
     gene            1583..2446
                     /locus_tag="ACG8LA_002909"
     CDS             1583..2446
                     /locus_tag="ACG8LA_002909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HFQ0205153.1"
                     /translation="MANITDFTEKQFEDRLEKNVERLTKNRLAVESPTAFLLGGQPGS
                     GKTSLRSAISEETQGNVVIIDNDTFKQQHPNFDELVKLYEKDVVKYVTPYSNRMTEAI
                     ISRLRDKGYNLVIEGTGRTTDVPIQTATMLQAKDYETKMYVMAVPKINSYLGTIERYE
                     TMYADDPMTARATPKQAHDIVVKNLPTNLETLHKTGLFSDIRLYNREGVKLYSSLETP
                     SISPKETLERELNRKVSGKEIQPTLERIEQKMVQNQHQETPEFKAIQQKMESLQPPTP
                     PIPKTPKLPGI"
BASE COUNT         1163 a          464 c          510 g          795 t
ORIGIN      
        1 aaagagggct tttatatatt aatcacaaat cacttatcac aaatcacaag tgattaatca
       61 caaatcactt gtgatttgtg attcttaatg atacaatatt actatacaaa aaaagaatgg
      121 ggcgtagtta tggagaagga aaaactaaaa atacttgaag aattaagacg tattttaaac
      181 aataaaaatg aagcaattat tatcttgaat aattacttta aaggtggtgt tggaaagtcc
      241 aaattatcga ctatgtttgc ttacttgaca gacaaattga atttaaaagt tttaatgatc
      301 gataaggact tacaggcaac attgacaaaa gacttagcaa aaacttttga ggtagaattg
      361 ccacgtgtca atttttatga aggcttgaaa aatggaaact tggcttcttc tattgttcat
      421 ttgactgata atttagactt gatccctggc acgtttgatt tgatgttact gccaaaatta
      481 actcgctcat ggacttttga aaatgaaagt agattgcttg ctactctttt agcaccttta
      541 aaaagtgact atgatctcat tattattgat actgtaccaa cgccaagcgt ttatacaaat
      601 aatgcaatcg tggcgagtga ttacgttatg atccctttac aagcagaaga agaaagtaca
      661 aacaacattc aaaactatat ttcctatttg attgatttac aagaacaatt taaccctgga
      721 ctagatatga tcggttttgt tccttattta gttgatacgg acagcgcaac gataaaatca
      781 aacctggaag aactgtacaa gcaacataaa gaagataact tggttttcca aaatattatc
      841 aagcgaagta ataaagtaag tacctggtct aaaaatggaa ttacagaaca caaaggctat
      901 gacaaaaaag ttttatccat gtatgagaac gtattttttg aaatgcttga gcgaattatt
      961 caattagaaa acgaaaaaga atagaatcac aaatcacaag tgattaatca caaatcactt
     1021 gtgatttgtg attgttgatg ataaaataag aataagaaga aatagaaaga agtgagtgat
     1081 tgtgggaaat ttaggcgcac aaaaagcaaa acgaaatgat acaccaatca gtgcaaaaaa
     1141 agatataatg ggagataaga cggttcgtgt tcgtgctgac ttacaccata ttataaaaat
     1201 tgaaacagca aaaaatggcg gaaacgtaaa agaagttatg gatcaagcct tagaagaata
     1261 tatacggaaa tatttacctg ataaacttta aaaaggagtg aaaatgaaat ggcagttacg
     1321 tatgaaaaaa catttgaaat agagatcatt aacgaattat cggcaagcgt ttataatcga
     1381 gtattaaact atgttttgaa ccatgaacta gatactaaaa atactcgttt actagaagtg
     1441 aatcttttaa atcaattaga agtggcacaa gaagttgatt tatttcaaca accatttgaa
     1501 gaattacaag ctattcatga gtattggcgg tcaatgaatc aatattcaaa acaaattttg
     1561 acaaaagaga aagtggctta acatggcgaa tattactgac ttcaccgaaa agcaatttga
     1621 agatcgttta gaaaagaatg ttgaacgact aactaaaaat agactagcgg ttgaatcgcc
     1681 aaccgctttt ttacttggtg ggcaaccagg atcaggtaaa actagtttgc gatcggcaat
     1741 ttccgaagag acacaaggaa atgttgttat cattgataat gatacgttca aacaacagca
     1801 ccctaatttt gatgaactag tgaaacttta tgaaaaagac gtagtaaaat acgttacccc
     1861 ttattctaat cgcatgacag aagcgatcat aagccgtttg agagataaag ggtataattt
     1921 agtgattgaa ggtacaggac gaacaacaga cgttcctatt caaaccgcaa caatgcttca
     1981 agccaaagat tatgaaacaa aaatgtatgt catggcagta cctaaaatca actcatattt
     2041 aggaacaatt gaacggtatg aaactatgta tgcagatgat ccaatgacag ccagggcaac
     2101 accaaaacaa gcgcatgata ttgttgtcaa aaacttaccg accaatttag aaacccttca
     2161 taaaacgggc ttatttagcg atataaggct ttacaataga gaaggagtga aactctattc
     2221 aagcttagaa acgccttcca ttagtccgaa agagacctta gaaagagaat taaatcgtaa
     2281 agtatcaggg aaagaaattc aaccgacttt ggagagaata gagcaaaaaa tggttcaaaa
     2341 tcaacaccaa gaaacccctg aatttaaagc aattcaacaa aaaatggaaa gcttgcagcc
     2401 acctacacca ccaataccca aaacacctaa acttccaggg atttaaacct taaaaaagta
     2461 aaagagtagt taccaaaaaa cggtaactac tcttttttta taaaaacatt tcctcatttt
     2521 ttaaaagctg atcgagaaat aaagcacaca actgtattct ttcttttttc agttggtaca
     2581 ttttgcagtc tgtaacgtgc catttactgt ttgttacctt aacatatcca gtcgaaaaca
     2641 caagggtata taaacgagca agctcgccct tgtgttttct ttgtgtctat gttgcgttct
     2701 cgtcacagca aacgacacga acacactggc gaaaatgaac caacaaaacg aaaaaagaaa
     2761 ggagcgtaca ctgtaattta tttctagctt ttaaaacatg aggaaaacag cttcacttcc
     2821 tcaaacgcct aacaaaaatg gttgtcaaaa aactaaaaat caaaaaaaga aaagaggaaa
     2881 agaaaatgga aaaaacaaaa aaattacaat tagaagattt tacagaaaat gg
//
LOCUS       DAZKKZ010000145         2848 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.154, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000145 DAZKKZ010000000
VERSION     DAZKKZ010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2848)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2848)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2848
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.154"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            658..990
                     /gene="traE"
                     /locus_tag="ACG8LA_002910"
     CDS             658..990
                     /gene="traE"
                     /locus_tag="ACG8LA_002910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV conjugative transfer system protein
                     TraE"
                     /protein_id="HFQ0205154.1"
                     /translation="MSYTGILSLEDICHYGKRCTATEKITKKLSTGQSKTVVQCKKYI
                     IQKDKVSEEMIYYAGKQKQIILKDPIPLKELYPTIKHVYDQNGVLIGRRKNGVLRCTA
                     KGMGRLIS"
     gene            1609..1908
                     /locus_tag="ACG8LA_002911"
     CDS             1609..1908
                     /locus_tag="ACG8LA_002911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5406 family protein"
                     /protein_id="HFQ0205155.1"
                     /translation="MKNYDPNIRLGTHTIKVSFQRWDYKGFVTFRRGGNCKGLDVLAL
                     DEDDLYDQKLTDNPIGFGLLPEDDEGNEWFNRIRQKSPILYRWVMNAVRYEGYRW"
     gene            1994..2398
                     /gene="tnpA"
                     /locus_tag="ACG8LA_002912"
     CDS             1994..2398
                     /gene="tnpA"
                     /locus_tag="ACG8LA_002912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605-like element ISEfa4 family
                     transposase"
                     /protein_id="HFQ0205156.1"
                     /translation="MELDTNNHSVFLLYYHLVLVTKYRRQVIDDEISDYAKTTFERIS
                     ESYHITLVEWNHDKDHVHIMFKAQPKTELTKFINAYKSASSRLIKRDFPRVKQFLWKE
                     MFWSKSFCLLTTGGAPIDVIKKYIQNQGNNHK"
     gene            2415..>2848
                     /locus_tag="ACG8LA_002913"
     CDS             2415..>2848
                     /locus_tag="ACG8LA_002913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0205157.1"
                     /translation="MEQLKAYKFRIYPTEEQEIFFAKSFGCVRKVYNLMLDDRKKAYE
                     EVKNDSSKKMTFPTPAKYKKEFPFLKEIDSLALANAQLNLDKAYKNFFRDKSVGFPRF
                     KSKKNPVQSYTTNNQNGTVALIDSKFIKVPKLKSLVRIKLHR"
BASE COUNT          997 a          428 c          554 g          869 t
ORIGIN      
        1 tccaacacaa aaaagagaac aaacgtttgc atgttgctgt tttttagtta taataatacg
       61 cgaagagagg taatttcatt ttttaaaaaa gctaaaaacc ttgatattac ttcttttcag
      121 gcaatacgaa tattattcgc ttacattttt ttgtataaat ttagttgttt taaatttaat
      181 tgtctgctac gcttgtgatg aattaatttt cgttctgcac ttttggacga taaatttgga
      241 caattgaaaa tacaaaaaaa agaaaggccc tgtgagactc ggaaggctgg taaccttcgt
      301 cgacgtccac aggtggcatt aagacaacct ttaatccctt aatgcgttta cctttcagtg
      361 ttacggtatt acccgcaacg gatttagtat aacagatatt caaaagtgat accacttttt
      421 ttggctgtgt taaggttaaa aatacgtgat attacgatga atctatgcct aagcataatg
      481 ttataaaaat gtccgtgtgg ctctttgccg tatgacgaac gctgaaatta gagggaacgc
      541 atgtttggat gcgttccctc ttttttgttt gtcatgaacg aaaatcaatt ctctattttt
      601 gaaaaataac aagaaaaact tattaaaaat atttaaagta agtgggtgga ttattttatg
      661 tcatatacag gaattttgag tctcgaagat atttgtcact acggtaaacg gtgtaccgct
      721 acagagaaaa tcacgaagaa actatcaact ggccaaagta aaaccgttgt gcagtgtaag
      781 aaatatataa tccagaaaga caaagtctca gaggaaatga tttattacgc tggtaaacaa
      841 aagcaaataa ttttaaaaga tcctatccct ttaaaagaac tatatccaac aatcaaacat
      901 gtttatgacc aaaacggtgt actgattggt cgaagaaaaa atggagtctt gcgttgtacc
      961 gcaaaaggga tggggcgttt aatcagctga attgatcatt ctcataactt gtattttatc
     1021 gtttttcgct tgcttgaaaa tattgtcgag acttctaaaa gaacttagaa ttactagaaa
     1081 aataaggagt agacttgatc tatcaacaat tcctttcggg gggtgacggg gtaggttttt
     1141 acgattggta acgtaaaaaa ttggtcaatc gagtaaatgc ccttgtttgg atagtggtga
     1201 aatgaatttg tgtaaataat atgcacagag taaacaagag ggaatttaga agttagacaa
     1261 gttagaatag cgcctagatt aatcatgagc agctactaag ggatctaggc tttgacgcaa
     1321 actcatggaa taaggagtag gtcttctcgt aatggggagg acgcacaaga aattgtgtcg
     1381 tgtgctgcag tacatgtaga tacttgcgag gacgttggtc attggatcaa tcgagcattt
     1441 accgatttct actagggttt ctcgtttcgg acgccataaa cgagtcgata ttttttatgt
     1501 atttttaagt aaacgaaaaa cgataaaata tgaacgagtc ctgaataaag tgaaaaaatt
     1561 gatataaaac atagagaaaa tgaaatttac gtaatggagg aatgacaaat gaaaaattat
     1621 gatccgaata tacgattggg cacacatact attaaggttt ctttccaacg ttgggattac
     1681 aaaggatttg tgacgtttag aagaggcgga aattgtaaag gattagatgt tttagcatta
     1741 gacgaggatg atttatacga tcaaaaattg actgataatc caattggatt cggcttgcta
     1801 cctgaagatg atgaaggtaa tgaatggttt aacagaatta ggcagaagtc gcccatcctc
     1861 tataggtggg tgatgaatgc cgttcggtat gagggttacc gttggtaact cgaagaccga
     1921 caactaaggc gtattgcctt tttattttgt cccatgttac aatcagtcta tacaagaaat
     1981 gagttgatat aacatggaat tagatacaaa taatcattca gtatttcttc tttattacca
     2041 ccttgtttta gtaacgaaat atcgtagaca agtgattgat gatgaaatat ctgattatgc
     2101 caaaactact tttgaaagaa tttcagaatc gtatcacatt actttagtgg agtggaatca
     2161 tgataaagac cacgttcata ttatgttcaa agctcaacct aaaacagaat tgacaaaatt
     2221 catcaatgcc tataaaagtg ccagctcaag attgataaaa cgtgactttc caagagtcaa
     2281 acaatttctt tggaaagaaa tgttctggtc taaaagtttt tgtcttctga caactggtgg
     2341 cgcaccaatt gatgtgatta agaagtatat ccaaaatcaa ggaaacaatc ataaatagaa
     2401 agtaggtgaa ctttatggaa caactaaaag catacaaatt cagaatctat ccaacagagg
     2461 aacaagaaat cttctttgcc aaatcttttg gttgtgtccg taaggtctac aatctaatgc
     2521 ttgatgaccg aaaaaaggcg tatgaagaag ttaaaaatga ttcttctaaa aaaatgactt
     2581 ttccgacacc agctaaatac aagaaagaat ttccgttttt gaaagaaatt gatagccttg
     2641 ctttagccaa tgcccaactt aatttagata aagcatacaa gaattttttt cgggataaat
     2701 ccgttggatt tccacgtttc aaaagtaaga aaaatcctgt tcagagttat acaacgaata
     2761 atcaaaatgg tacagttgct ttgattgata gtaaattcat caaagttcct aaattgaagt
     2821 cattagtaag aattaagctt catagaca
//
LOCUS       DAZKKZ010000146         2821 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.156, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000146 DAZKKZ010000000
VERSION     DAZKKZ010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2821)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2821)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2821
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.156"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..640
                     /locus_tag="ACG8LA_002914"
     CDS             <1..640
                     /locus_tag="ACG8LA_002914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004612033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0205158.1"
                     /translation="KNVAYSYANSKEKVLSGVNQKFELGKFYAIVGKSGTGKSTLLSL
                     LAGLDKPQTGKILFKNEDIQNKGYSNHRKNNISLVFQNYNLIDYLSPIENIRLVNKSA
                     DESILFELGLDKKQIKRNVMKLSGGQQQRVAIARALVSDAPIILADEPTGNLDSVTAG
                     EIINILKTLAKDRNKCVIVVTHSKEVADSADIILELSGKKLKKVNKMNLEVE"
     gene            640..2016
                     /locus_tag="ACG8LA_002915"
     CDS             640..2016
                     /locus_tag="ACG8LA_002915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFQ0205159.1"
                     /translation="MIKNAFAYVTRKSLKSLIIILVILSMSTLSLISLSIKDATDRAS
                     KETFANITNSFSMEINRQVNPGTPRGGGNVKGEDIKKISQTDSIDSYVKRINSVADLV
                     DYDIIETQETLANQSPERAKNFKRTVMLTGVNDSTKETKFVSEAYKLVEGKHLENEDK
                     NKILMHKDLAEKNNLKVGDKIKIKSNLFDADNEKGADETVEVEIKGLFDGHNSGGVSA
                     AQELYENTLITDIHTAAKVYGNTEDTAVYQDATFFVKGDKNLDSVIKDLGKLDINWRE
                     YNLIKSSSNYPALQQSISGIYSISNKLFFGSLIFAGVVVSLLLFLWMNARKKEIAVLL
                     SLGISKLEIFGQFLIEMVFISIPAFVGSYFLAQYTADKLGNNILNKVTGDIAKQIAKQ
                     SASSQLGGGAEAEGFNKTLSSLDINVLPKFMIYVVIFMSLVLLVSLIISSFNILRRNP
                     KELLIDNN"
     gene            2146..2559
                     /locus_tag="ACG8LA_002916"
     CDS             2146..2559
                     /locus_tag="ACG8LA_002916"
                     /inference="COORDINATES: protein motif:HMM:NF013068.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFQ0205160.1"
                     /translation="MARKKRNPDAEKLAESILNTYQPESVEDMQDVLKDVFGPLFEKM
                     LQGELNNHLGYDAHSKEPKKHDNRRNGYGNKTLKTSFGKVNIDVPRDREASFEPELIP
                     NRKRDVSDIADCRQKLFQTRNSSLEQLFIYFVSNF"
     gene            complement(2584..2821)
                     /locus_tag="ACG8LA_002917"
                     /pseudo
     CDS             complement(2584..2821)
                     /locus_tag="ACG8LA_002917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611630.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         1065 a          382 c          503 g          871 t
ORIGIN      
        1 aaagaatgta gcatatagtt atgcaaattc taaagaaaaa gttttgtcag gagtaaatca
       61 aaaatttgaa cttgggaagt tttatgcgat agtaggaaag tcaggaacag gaaaatctac
      121 acttctttcc ttacttgctg gacttgataa acctcaaaca ggaaaaatat tgtttaagaa
      181 tgaagatata caaaataaag gatatagtaa tcatagaaaa aataatatat ctttagtatt
      241 tcaaaactat aatttaatag attatttatc accaattgaa aatattagat tagtaaataa
      301 atcagcagat gaaagtatct tgtttgaact aggtttagat aaaaaacaaa taaaaagaaa
      361 tgttatgaaa ttatctggtg gacagcaaca aagagtagct attgctagag cattggtatc
      421 agatgctcca ataatactag ctgatgagcc tactggtaat ctagacagtg ttactgctgg
      481 agaaataatt aatatattaa agacattagc taaagataga aataaatgtg taatagttgt
      541 aacacatagt aaggaagtag cagattctgc ggatatcatt ttagaactaa gtggtaaaaa
      601 gttgaaaaaa gtaaataaaa tgaatttgga ggttgaataa tgataaaaaa tgcatttgct
      661 tatgtaacta gaaaaagttt aaaatcatta attatcatat tagttatttt atctatgtca
      721 actttaagtc tcattagttt atctattaaa gatgctacgg acagagcttc aaaagaaaca
      781 tttgctaata taacaaatag tttttctatg gagataaata gacaagtaaa tccaggaaca
      841 cctagaggtg ggggaaatgt aaaaggtgaa gatattaaaa agatatctca aacagatagt
      901 atagactcct atgtaaaaag aataaacagt gttgcagatt tagttgatta tgatattatt
      961 gaaactcaag agactcttgc gaatcaatca cctgaaagag caaagaattt taaaagaaca
     1021 gttatgttaa ctggggttaa cgactcaaca aaagaaacaa aatttgtatc agaagcatat
     1081 aaattagtag aaggaaagca tttagaaaat gaagataaaa ataaaatctt aatgcataaa
     1141 gatttagctg aaaaaaataa ccttaaagtt ggagataaga taaaaataaa atctaattta
     1201 tttgatgctg ataatgagaa aggtgcagat gaaacagtag aagtagaaat taaaggtcta
     1261 ttcgatgggc ataatagcgg tggagtaagt gcagcacaag aactatacga aaatacatta
     1321 atcactgata ttcatacagc tgctaaagtt tatggtaata ccgaagatac agctgtatac
     1381 caagatgcaa cattctttgt aaaaggtgat aagaatcttg atagtgtaat aaaagatctt
     1441 gggaaattag atataaattg gagagaatat aatttgatta aaagttcatc aaattaccct
     1501 gcattacaac aatctatatc aggtatttac tcaatttcaa ataaattatt ttttggctca
     1561 ttaatatttg caggagttgt agtttcatta ttattattct tatggatgaa tgctagaaag
     1621 aaagaaatag cagtattact atcattaggt atatcaaaat tagaaatttt tggtcaattc
     1681 ctaattgaga tggtatttat atcaatcccc gcattcgttg gttcctattt cttagctcaa
     1741 tatacagctg acaagcttgg gaataatata ttgaataagg ttactggtga tatagctaaa
     1801 caaatagcta aacaatctgc atctagccaa ttaggtggtg gggcagaagc tgaaggattt
     1861 aacaagacat tatcaagttt agatatcaat gtattaccta aattcatgat ttatgtagtt
     1921 atatttatga gtttagtact tcttgtatca ttgattattt cttcattcaa tatattaaga
     1981 aggaatccaa aagaattatt aattgacaat aattaaaatt ttcggtgctt tttagcacca
     2041 aaaatgagag tgtaatataa accgtgtaag taaccatcaa tcctaggcgg gtggttgctt
     2101 cacggttttt atttttctaa aataagatca agaggtgatt acacgatggc tagaaagaaa
     2161 agaaatcctg atgctgagaa gttagctgaa tccattttga atacttatca acccgaatct
     2221 gtagaggata tgcaagatgt tttaaaagat gtgtttggtc ccttatttga aaaaatgctt
     2281 caaggagaat tgaataacca tttagggtat gacgcccatt ctaaagagcc aaagaaacat
     2341 gacaatcgac gaaacggtta tggcaataag acgcttaaaa cgagctttgg taaagtaaac
     2401 attgatgttc ccagagaccg ggaggcttct tttgaacctg agttgattcc taatagaaaa
     2461 cgagatgtct ccgacatcgc agactgtaga caaaagctgt tccaaactcg taactcgagc
     2521 ttggaacagc tttttatcta cttcgtttcg aatttttgaa caaaaaaata aaggctcctt
     2581 gcctttccat agccaggtgg ctaatttctt taaattcatt gcagcaaaca ctagcatcgt
     2641 atgcgtcgcg actttttcca agcctcgata cttggtccaa cgcatcccat gcttttcttt
     2701 tgcatccgca aatattcgtt caatcgtttg tttccgtttt ttgtaaattg atttattcag
     2761 atctgttagg cgaagatgtt ccacttcatc catcagatct ccccaaacat gtctcgtgat
     2821 g
//
LOCUS       DAZKKZ010000147         2767 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.157, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000147 DAZKKZ010000000
VERSION     DAZKKZ010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2767)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2767)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2767
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.157"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..876
                     /locus_tag="ACG8LA_002918"
     CDS             <1..876
                     /locus_tag="ACG8LA_002918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014334286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFQ0205161.1"
                     /translation="LTIFFVHRHEDVLRVAKKISGPIVRVKDFTREIAKGDYTSLSPE
                     KTDIKELDELISSVNALSVQLENQQDIRNQLSSDIAHEIRTPLTTLKGSLEAMIDGIW
                     EIIDDRIQSCYDEVNRITRLIGSIDKINEIESHQDSLNKISFDLYALAENISSNFEAL
                     FAKKNIYYALNGDSLFITADRDKISQVITNLLSNAVKFTPPEGTITLKIRNEKNQALL
                     TIADTGEGIHPKEINRIFERFYMSDLSRNSFLGGQGIGLSIVKSIIKAHNGTITVKSD
                     YGKGSTFTVILPVKR"
     gene            complement(1046..2218)
                     /locus_tag="ACG8LA_002919"
     CDS             complement(1046..2218)
                     /locus_tag="ACG8LA_002919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014334285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome D1 domain-containing protein"
                     /protein_id="HFQ0205162.1"
                     /translation="MGLLLAACGQEESTSSQNSSQQAIVSTSQETSESQSSSKEENKE
                     QTEAYYTSDTGSVTKVDAQTHEVVDTIAIDGSAHNVQISPDEKVIGVTIVPSEGHAED
                     SSGSNESMEMEHDEDSDTSMSNESMEMGQDEDSDTSMSNESDDEKGIAAFYDAETGEK
                     LAEVEVGSHPAHIVFTNDGNYAAVSNNGENTVSVIDVSTYEVVETIPTGEGPHGFRIA
                     EDGKTAYVANMGEDTVSVLDLESMEEVNRITVGSTPATTGITSDGQTLLVTLNGENAL
                     AIVDLTTNKVEKVAVGNGPIQLFVQHDDQYVFVANEGTEENPSNTVSKVDLNSNEVVE
                     TIEVGSGAHGVVISEDDKYTFVTNAFDDTVSVIENETSEVIVTVEVGETPNGITLK"
BASE COUNT          826 a          539 c          442 g          960 t
ORIGIN      
        1 ttaacaattt tttttgtgca tcgacatgaa gatgtactcc gggttgctaa aaagataagt
       61 ggacctatag tgagagtaaa ggattttaca agagaaattg ctaaaggaga ttacacaagt
      121 ttatctcctg aaaaaactga tatcaaggaa ctagatgaac tcatttcatc tgtaaatgct
      181 ctttctgttc aacttgagaa tcaacaagat atcagaaacc aattatcttc tgatatcgct
      241 catgagatca gaactccatt aacaacacta aaaggaagtc tggaagctat gatagatgga
      301 atatgggaaa taatagatga ccgaattcaa agttgttatg acgaggtgaa ccgtattacc
      361 cgccttatag gaagcattga taaaattaat gaaattgaaa gtcatcagga tagtttaaac
      421 aaaatatctt tcgatttata tgctctcgcg gaaaatatat cttctaattt tgaagctctt
      481 tttgctaaga aaaatattta ttatgcatta aatggggatt ctctattcat taccgctgat
      541 agggacaaaa taagtcaagt cattacaaat cttttatcca atgctgttaa atttacaccc
      601 ccagaaggaa caataactct aaaaattcgc aacgaaaaaa atcaagcttt attgactatc
      661 gcagatacgg gagaaggaat tcacccaaaa gaaattaatc gtatttttga gaggttttat
      721 atgtctgatc tttcaagaaa tagttttcta ggcgggcaag gaattggctt atctatcgta
      781 aaaagtatca taaaggctca taacggaacc ataacggtca aaagtgatta tggaaaaggt
      841 tctacattta ccgttattct tcctgtcaaa agatagtaat catcaaaaaa agcggttcac
      901 ttttatgtaa agtgaaccgc tttttcagct tcatgataaa gttttccatt taatttagga
      961 ctaattaaga tttttaaacg ttagaatatt tatccctttt cagaaatcat taagttgatt
     1021 ttttagttta acttaacact aataatcatt tcagagtaat cccatttggt gtttcaccaa
     1081 cctcaaccgt gacaataact tcactagtct cattctcaat aacactgacc gtatcatcga
     1141 atgcattcgt gacaaaggtg tatttatcgt cttcactaat gacaactcca tgtgcaccgc
     1201 tacccacttc gattgtttcg accacttcat tactatttaa atcaaccttt gaaacggtat
     1261 tggaaggatt ctcttcggta ccttcatttg ccacaaatac atattgatca tcatgttgaa
     1321 caaacaactg gataggacca tttccaactg ctactttctc aactttattg gttgtcagat
     1381 caacgattgc taacgcattt tctccattta atgttactaa gagcgtttgt ccatctgagg
     1441 taataccagt tgtagctgga gtactgccaa cagttattct attaacttct tccatacttt
     1501 ctaaatcaag gacgcttaca gtgtcttcac ccatattggc aacgtaagcc gtttttccgt
     1561 cttcagcgat tctaaaaccg tgtggacctt cgcctgttgg gattgtttca accacttcat
     1621 aagtagatac atcaatgact gaaacagtgt tctctccatt attggaaact gctgcatagt
     1681 tgccatcgtt agtgaaaacg atatgagcag ggtgactccc tacttcaact tctgcaagtt
     1741 tttcacctgt ttcagcatca taaaaagctg caataccttt ttcatcgtca ctttcattac
     1801 tcatactagt atcactatct tcgtcctgtc ccatctccat actttcattg ctcatactgg
     1861 tatcactatc ttcgtcgtgt tccatctcca tactttcatt actacctgaa ctgtcttcag
     1921 catgcccctc gctgggaaca attgttacac caatgacttt ttcatcaggt gaaatttgta
     1981 cattatgtgc ggatccatcg atggcaatcg tatccacaac ttcgtgcgtt tgagcatcta
     2041 cttttgtaac acttccagta tcggaagtgt aataggcttc tgtttgttcc ttattttctt
     2101 ctttagaact agattgagac tcactagttt cttgtgacgt tgatacaatt gcttgttgag
     2161 aagaattttg actacttgtt gactcttctt gaccacaagc tgcaagcaag agacccactg
     2221 acgacaatag tgctaaagtg attctttttt tcattttaat atcccctttt ttactacgta
     2281 ctttttactt ttcgtactat ttttattgct ctataattgc ctgaattatt cataattttt
     2341 ccgtaggttt ctgaaaagat tgtggtactg cgttcctgat ttctcttctt tactttcatg
     2401 gtggtgcata atttatcccc ttgctttgat ttattttatg tttctgtttt tataataata
     2461 tatgaatgtg ttgattttat gtagaaaaaa accatatcaa aaagccaaga tttgtatatg
     2521 atcttggctt tttgatatga atagttcatt tccggaatat atttttgaga aaactcagtt
     2581 cgagcatgaa acttcagact tacccaacta acttttcaat attttcttct tttgttggta
     2641 ttcttcgtct ggttctgttg cgaagtttga aaatcaaacg cgccctctct gaactccaaa
     2701 tatcttaggc tgttattccc attaatacct tgatttcagt agacaccgaa aagccgaaga
     2761 gcgttcc
//
LOCUS       DAZKKZ010000148         2761 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.158, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000148 DAZKKZ010000000
VERSION     DAZKKZ010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2761)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2761)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2761
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.158"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            194..1233
                     /locus_tag="ACG8LA_002920"
     CDS             join(194..691,694..1233)
                     /locus_tag="ACG8LA_002920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611651.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HFQ0205163.1"
                     /translation="METERQIRELEKAMNTTDNRRLYERFLAVKLVLEGHTRKEAGHT
                     IGRDEHTVSHYVKNYCHNGIQGLVSKKQSGRPSRLTDEQEAELVQIVAYHTPEEVGFK
                     SRANWTLAIVCDLILREWSYGYTQKGVADLLHRLGLSWTRPTYTLKKADSKKQQVFLE
                     ETFPSLKKLLNSDIDHLLFEDETMIRDYQAIGCTWFLRGHQRKIPTYGQHKGVKLIGT
                     LDYETGRIICTEEGAYDAAAFLRFLERTLREYPTGKIVMVLDNALIHHAKLIQSFLEE
                     NARRLALIFLPPYSPQLNLMEGVWKWLKESVINNVFFDHVQKIKQSVRGFLADVNERP
                     LEVIDRLCVRM"
     gene            1246..2184
                     /locus_tag="ACG8LA_002921"
                     /pseudo
     CDS             1246..2184
                     /locus_tag="ACG8LA_002921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion protein ImpB"
     gene            2177..2524
                     /locus_tag="ACG8LA_002922"
     CDS             2177..2524
                     /locus_tag="ACG8LA_002922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0205164.1"
                     /translation="MIEYNDRGRLKWSGFYLSDHTERINADNVQRANHNLAKEQMTTE
                     EIAKILRTAVIKNRPVCIQKEERNAEGYYPDDVVGKIIGYDELGVFVEEEKVHYDEIR
                     NVSFSELLKWSQI"
     gene            2521..2703
                     /locus_tag="ACG8LA_002923"
     CDS             2521..2703
                     /locus_tag="ACG8LA_002923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0205165.1"
                     /translation="MNIIKKYEFGYITYEQLIEELWGYGQQLINEVGIDCFCFYIESG
                     AGYHKNRYYIFPYPPK"
BASE COUNT          954 a          502 c          602 g          703 t
ORIGIN      
        1 tgtgatagag aaataacaat ccgttattga cgcaaatcct tgaatcaacc cgaaaaaaat
       61 ttgattttga tcgggtctag tttcgtgcgc ttcaaaacat attactcaat aaagaaaatc
      121 ttaaatttca tcttgactta tcaccattag actataggcg tatactaaag aaaacacttg
      181 aggagtgggg aacatggaaa cagaacgcca aatccgtgaa ttggaaaaag cgatgaatac
      241 gacagacaac cgccggttgt acgagcgttt cctggcagtc aagttggttc ttgaaggcca
      301 cacccggaaa gaagccgggc acaccatcgg ccgcgacgag catactgtca gccactatgt
      361 gaaaaactac tgccataatg gaatccaagg tttagtctcc aaaaaacaaa gcggacgacc
      421 ttcacggctg acagatgaac aggaagcgga actggtccaa atcgtcgcct accacactcc
      481 ggaggaagta ggtttcaaat cccgtgccaa ttggacattg gcgattgtgt gtgacctgat
      541 tctccgggaa tggagttatg gatatacgca aaaaggcgtg gcggacctcc ttcaccggct
      601 aggactaagc tggacccgtc cgacgtatac cctcaaaaaa gcggattcca agaaacaaca
      661 ggtatttttg gaagaaacct tcccgagcct aaaaaaaaat tgctgaatag cgatattgac
      721 cacctcctat tcgaggacga aaccatgatc cgggattacc aagccattgg ctgcacctgg
      781 tttctccgcg gccaccagcg aaaaatcccc acttatggac aacacaaagg ggtaaaattg
      841 ataggcacct tggattatga aaccggtcgg atcatttgta cagaagaagg ggcatacgac
      901 gcagcggcct tcctccgttt tctggagcgg acgttgcggg aataccccac cggaaaaatc
      961 gtgatggtat tggataatgc ccttatccac cacgccaagc tgatccagtc ttttcttgaa
     1021 gaaaacgcta ggcgcctggc actcatcttc ctccctccct acagccctca gttgaaccta
     1081 atggaaggcg tttggaagtg gctcaaggaa tcggtcatca acaatgtttt ttttgaccac
     1141 gtccagaaaa tcaaacagtc ggtccgcggt ttcttagccg atgtaaacga gcgtcccctt
     1201 gaggtgattg accgactgtg cgtgcggatg taaagtattt aattcaacct atatagttca
     1261 ggaacaagaa gcgagagaag aagagaatta gctaaaataa tcaaagatga gattcagaaa
     1321 gaaacaggtc taatagcaac agtcggaata ggagataacc cattattagc taaacttgca
     1381 ctggacaatg aagcgaagag tagtaaagaa tttatagctg agtggactta tgagactgta
     1441 cctgaaaaaa tatggaaaat aaacgagatg actgactttt ggggcattgg atcacgcatg
     1501 aaaaaaagat tgaatcatat gggaattatg agtatagaag atttagcaaa ttggaatccc
     1561 tacacaatta aaagtcagtt aggtgtaatc ggactccagt tatatttcca taccaatgga
     1621 attgatcgta cggatattgc tattccacca gaaccaacca aagaaaagtc ttatgggaat
     1681 tcacaagttc taccaaaaga ttatacgagg agagaagaag tagaactagt agtcaaggag
     1741 atggcagagc aagtagccat tcgaattaga caacacaatt gcaaaactgg ttgtgtacgc
     1801 ttagcaattg gtacgtcaat tttggaagaa aaatcaggtt tctcgcacca gatgaaaata
     1861 ccaattacag ataatacgaa agaattacaa aattattgtc tttttttatt caataagttt
     1921 tatgaggggc aggaagtacg acatatagga gtaacttata gcagattagt atacacagat
     1981 tccctacaat tagatttatt tagtgatcca agaaaaaaga ttgctgaaga aaatttggat
     2041 aggattattg ataagattag acaaaaatat ggatttacag ctattataca tgcttcatct
     2101 atgttagaag gtgcaagaag tattacgaga agcactttaa taggaggaca cgcaggagga
     2161 ttaggaggtt tgcataatga ttgaatataa cgatagagga cgtttaaaat ggtcgggatt
     2221 ttatttgtct gatcatactg aaagaatcaa tgcagacaat gtacaacgtg ctaatcataa
     2281 tttggcaaaa gaacaaatga cgactgaaga gattgcgaaa atactgagaa ctgctgtcat
     2341 aaaaaataga cccgtctgca ttcaaaaaga ggaacgaaac gctgaaggtt actatccaga
     2401 tgatgtagta ggaaaaatta ttggatatga cgagcttggt gtatttgtgg aagaagaaaa
     2461 agttcactat gatgaaatta ggaatgtttc tttctcggaa ttattaaaat ggagtcagat
     2521 atgaacatta ttaaaaaata cgaattcggt tatattacgt atgaacagct aatagaggaa
     2581 ttatggggat atggtcaaca attaattaat gaagtgggga ttgattgctt ttgtttctat
     2641 attgaatccg gagcaggata ccataagaac agatactata tatttccata tccaccaaaa
     2701 tagtctctta gatattttta aattttctcc aaatactttc aattattgtg aaatatttcc
     2761 c
//
LOCUS       DAZKKZ010000149         2474 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.159, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000149 DAZKKZ010000000
VERSION     DAZKKZ010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2474)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2474)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2474
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.159"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            580..1539
                     /locus_tag="ACG8LA_002924"
     CDS             580..1539
                     /locus_tag="ACG8LA_002924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HFQ0205166.1"
                     /translation="MTYTHLTPTELVMIEAYFNQSHSVSKVAHLVQRSRQTIYNVYRF
                     LKSGGSAISYYEQYKKNKRNCGRRPIVLPDGQQEYIQKKVAQGWTPDVLIGRAEFPIA
                     CSVRTLYRMFKDKTFDPHDLPMKGKRKPNGHKEKRGKQAFRRSIQDRTTDYIQFNHEF
                     GHLEGDTIVGGKHKSAVITLVERLSKVIITLKPAGRQAIDIENRLNQWFQSVPKHLFK
                     SITFDCGKEFSNWKKISNTNDISIYFADPGTPSQRGLNEHSNGLLRKDGLYKAMDFNK
                     VSETFIQSVASKRNHIPRKSLHYRTPLEVFLSYVGKDDLSSLI"
     gene            complement(1526..2131)
                     /locus_tag="ACG8LA_002925"
     CDS             complement(1526..2131)
                     /locus_tag="ACG8LA_002925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0205167.1"
                     /translation="MINSAYFHIKYLKKYEYEEVVLDYGLNRQSFLIYAINNGNLPSN
                     KKNIIIETYAYLEGGSKKLIKSCNIEYQLSVGEIKCVFEEDLELDLKKIFASIHDYIG
                     LIYKIIEDDKQTELNMCYFDREQDFFYYGGMGGGSIVPKINLVELDVNNYRELYVFNS
                     LDFEIPMKQMKNIDIHILPSESCQIEYSIEYFYKVSFVKLS"
     gene            complement(2371..>2474)
                     /locus_tag="ACG8LA_002926"
     CDS             complement(2371..>2474)
                     /locus_tag="ACG8LA_002926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HFQ0205168.1"
                     /translation="WTCPICHTHHDRDINASINILTEGLRLHSMGLA"
BASE COUNT          824 a          406 c          384 g          860 t
ORIGIN      
        1 acaataaatg aagacttttt tattgttaat tgtttatttt tctattatta gatatgaaaa
       61 tcgcatttag ataaaataga aaaatatgaa tatattttaa atattaagat gagagtcatt
      121 aacttatgat agtagtcaat ttgcttttca ctaattacaa aatatgtgat ataggaagtt
      181 tagttattgt tctcataatg ccatcctgtt tttagattat ctagtaattt ttttgttatt
      241 taaaattagg agcagtgcca attgttttaa ttttaaaggc tttttttata tcttctaaat
      301 tagaagatat ttgtatatca atatggaata tattaccttt tttgtatttt tttatgttat
      361 ctttagctaa aacatcaaat acatgtcctt gaaattgtat cgaggcagct ggatttagtt
      421 taaattgagg aaactttacc acagctgatt caaaacactt gtcacatttt tttatttttt
      481 taccttcgcc gattgtaaaa ttaagctaga caactaaaaa agtcatttgt gctacactca
      541 aaatagttcc gtcgaaagaa ttataaggag tgagtacaaa tgacctatac ccatcttaca
      601 ccaactgaac tcgtaatgat agaagcttat ttcaatcaat cacactctgt ttcaaaagta
      661 gcccatctgg tacaacgttc tcgacaaacc atttataatg tctatcgttt tcttaaatct
      721 ggtggaagcg caataagcta ctatgaacaa tataagaaaa acaaacgtaa ctgcggaaga
      781 cgtccgattg tgttaccaga tgggcaacaa gaatacattc aaaaaaaggt ggctcaaggg
      841 tggactccag atgtccttat tggtcgagca gagtttccta ttgcttgttc ggtacgtaca
      901 ctatatcgga tgtttaaaga taaaaccttt gaccctcacg atttaccaat gaaagggaaa
      961 agaaaaccaa acggacataa agaaaaaaga ggaaaacaag cttttcgccg ttcgattcag
     1021 gatagaacaa ctgattatat acagttcaat catgagtttg gtcacctaga aggtgacacc
     1081 attgtcggtg gaaaacataa aagtgcggtg atcacgttag ttgagcgatt atctaaagtg
     1141 atcatcacct tgaaacccgc tggtaggcaa gctatagata ttgagaatag actgaatcaa
     1201 tggtttcaat ctgtaccgaa acacttgttt aaatccatca catttgattg tggaaaagag
     1261 ttctcgaatt ggaaaaagat tagtaatacc aatgatattt cgatttattt cgctgatcca
     1321 ggaacacctt ctcaacgagg actaaatgaa cattcgaatg gcttattacg taaagatggc
     1381 ttatataaag ctatggattt taataaggta tccgaaacct ttatccaatc ggtggcatca
     1441 aaacgaaatc atattcctag aaaatcatta cactatcgca caccattgga agtatttttg
     1501 agttacgtag gtaaagatga tttgtctagc ttaatttgac aaacgaaact ttgtaaaaat
     1561 attcgattga atattctatt tggcacgact cacttggcag tatatgtatg tcaatatttt
     1621 tcatctgttt cataggtatt tcaaaatcta aactattaaa aacatataat tccctgtaat
     1681 tatttacatc taactctact aaatttatct ttggaacaat agatcctcca cccattccac
     1741 cataataaaa aaaatcttgt tctctatcaa aatagcacat attaagctca gtttgtttat
     1801 catcctcaat aattttataa atcaaaccta tataatcatg aatgctggca aaaatttttt
     1861 ttaagtcaag ttctaaatct tcttcgaaaa cacatttaat ttctcctact gataattgat
     1921 actctatatt acatgactta attagttttt tagatccccc ctccagatag gcatatgttt
     1981 caataattat gttcttttta ttgcttggca aatttccgtt atttattgca taaattaaaa
     2041 atgactgtct atttagccca taatctaata caacttcttc atactcatat ttctttaaat
     2101 atttaatatg aaaatatgct gaattaatca aaactcgagt gttactgttg ttatttattg
     2161 ttgttctatt gtgtataaaa ttgtataggt tgtcatattt tcttggttta gtgaactact
     2221 caccacttag ctaaacctaa cggtttctta cgtttgaagt gggagcttct tgggaagaga
     2281 gcatacttga tagcgtatta ctttactaac agaggtgcct cttatttacc aagctatccc
     2341 cgtagttcct acggttcttg tttatttgat ctaagccaat cccatagagt gtagccttag
     2401 accttcggtc aggatattga tactagcgtt gatatctcgg tcatgatgag tatgacaaat
     2461 agggcaagtc catt
//
LOCUS       DAZKKZ010000150         2442 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.160, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000150 DAZKKZ010000000
VERSION     DAZKKZ010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2442)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2442)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2442
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.160"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            139..2292
                     /locus_tag="ACG8LA_002927"
     CDS             139..2292
                     /locus_tag="ACG8LA_002927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan D,D-transpeptidase FtsI family
                     protein"
                     /protein_id="HFQ0205169.1"
                     /translation="MMKDFMKKILNTSWLEKIRKGAQEPKNKTFRRSHVPFRLNFLFF
                     IIFTLFVALIARLGYLQIVNGEEMEARVKSTSTITVQESTPRGMIYDSTGKALVTNKA
                     NQAITYTRGTQVTAKDLLEIATKLNSLIDVPVDENLTDRDKKDFWLADPKHLKEATKR
                     LSAKEKQLGNSEQYSAMVNKVTADEINLNEEQLKIATIFKRMNSAYELNTVYIKNSGV
                     TDQELAVVAERASELPGVSTGTDWTREYNAASSLKSILGSVTTEKQGLPADEAEKYLA
                     KGYSRNDRVGQSYLEKQYEDVLQGTKTQYEVSLDNEGNVSNQKEIFSGEKGSNLMLSM
                     NAEFQSKVEEILKRNYQTLINNGKAQYSPGAYAVAMNPQTGEVLAMTGFSHEQGSKEI
                     TENALGTITSAFDPGSVVKAGTLTAGWASNAISGNQVLIDEPIRLQGASEKSSVFNRS
                     GQVALDAVKASELSSNTYMIKVALKMLGLDYTPGMGLPSLDEEAKAYQQLRDSFKEFG
                     LGTTTGIDLPNESPGISRSVDYMKKFNADNGKEWYAPGNFTDLAFGQFDTYTPIQLAQ
                     YASTVANGGKRVQPHLVKAIYGNDENGNLGEVKKEIGTTVENTVNISAENMAILREGF
                     HQVVHGTDPYTTAKPLASAKMDLSAKTGTAETVAEGHPDIATVNSNIVAYGPTDNPEI
                     AISVVLPNLLDEQDHINLTIAKEIMDAYYDMFMAK"
BASE COUNT          834 a          427 c          541 g          640 t
ORIGIN      
        1 agtgattgct gtgaaacaaa aagttgattt tatcttgaaa ttaggtaaag aatttcttgc
       61 tccgcccatt ttttcttttt tattaagaag tttttgggta caatgaagca tgaatgtaaa
      121 taggcggaag gataggaaat gatgaaagat tttatgaaaa aaatattaaa tacttcttgg
      181 ttagaaaaaa taagaaaagg tgcacaagaa cctaagaaca aaacgtttcg ccggtcccat
      241 gttccttttc gcttaaattt tctttttttc attatattta cgttatttgt tgcgttgatt
      301 gctagattgg gttatttgca gatcgtgaac ggcgaagaga tggaggcgcg agtgaagtct
      361 acttctacga ttacggtcca agaaagtact cctcgcggaa tgatctacga ctccacagga
      421 aaagctttag ttacgaataa agcgaatcag gccatcacat atacgagagg aacacaagtt
      481 acggctaaag atttgcttga aatcgcaacg aagctgaact cgctgatcga tgttccggta
      541 gatgaaaatc tgacagatag agataaaaaa gatttttggc tggctgatcc caaacatttg
      601 aaagaagcca caaaaagact ttcggcaaaa gaaaagcaat tagggaacag cgaacaatat
      661 agtgcgatgg tcaataaagt cacagctgat gagattaatt taaacgagga gcaattaaaa
      721 attgctacca tctttaaacg gatgaatagt gcatatgaat taaacactgt ctatatcaaa
      781 aactctggtg ttactgatca agagttagct gttgtggcag aacgcgcttc tgaacttcca
      841 ggagtttcga ctggcacaga ctggacacga gaatataatg cagcaagttc actgaaaagt
      901 attcttggca gtgtgacgac tgaaaagcaa ggacttccag cagatgaagc agagaaatac
      961 ctagcaaaag gttattctcg gaatgaccgt gtaggacaaa gttatttgga aaaacaatat
     1021 gaagatgtcc tgcaaggaac caaaacccaa tatgaagttt cccttgataa tgaaggaaat
     1081 gtttcgaatc aaaaagaaat cttctctggg gaaaaaggtt ctaatttaat gttatctatg
     1141 aatgcagaat tccaatcaaa agtagaagaa attttgaaaa ggaattatca aacattgatc
     1201 aacaacggca aagcacagta ttcgcctggt gcttatgcag tggctatgaa tcctcagaca
     1261 ggagaagtgc tagcaatgac tggtttcagt catgaacaag gttccaaaga aatcaccgag
     1321 aatgctttag gcacgattac tagcgccttt gatccagggt ctgtagtcaa ggctggtact
     1381 ttgacagcag gctgggcaag taacgcgatc agcggaaatc aagttttgat tgatgagccg
     1441 attcgtctgc aaggtgcttc agaaaaaagc tctgtcttta atcgaagcgg acaagttgct
     1501 cttgatgcag tcaaagcatc ggaattgtct tctaatacgt atatgatcaa agtggcgtta
     1561 aagatgttag gactagacta tacacctgga atgggactac ctagtttaga tgaagaagct
     1621 aaagcttatc agcaattgag agactctttc aaagagtttg gtcttggtac aacgactggg
     1681 atcgatttgc cgaatgaatc tcctgggatc tcacgttctg ttgattatat gaagaagttc
     1741 aatgcggata atggcaaaga atggtatgct ccaggtaact ttaccgattt ggcatttgga
     1801 cagtttgaca catatacacc aatccaatta gctcaatatg cttcaacagt cgctaatggc
     1861 gggaaacgag tacagccgca cctagtcaaa gcgatctatg gcaatgacga aaatggaaac
     1921 ttgggtgaag tgaagaaaga aattggcaca acagtagaaa atacggtcaa tatttctgca
     1981 gaaaatatgg cgatcctccg tgaaggattc caccaagttg tccatggtac cgatccttac
     2041 acaacagcca aaccattagc cagtgcgaaa atggaccttt ccgcaaaaac agggactgca
     2101 gaaacggttg cggaaggtca tccagatatt gcgacagtca atagtaatat cgtggcatac
     2161 ggaccaacag acaatccgga aattgccatc agtgttgtct tgccgaactt attagacgaa
     2221 caagaccaca taaacttgac gattgctaaa gaaataatgg acgcgtatta tgatatgttc
     2281 atggcaaaat aaaaaagagg tcgtgaaaaa gccgcttagt ttcgagtatg aagaaaaatt
     2341 ttgtgaaaat agcttctcac atttttgctt aaatttgact tcataccgag aaactggctt
     2401 ttgaacaccg tttactcggc aaaaaaggtt gtgacaaaaa tt
//
LOCUS       DAZKKZ010000151         2438 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.161, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000151 DAZKKZ010000000
VERSION     DAZKKZ010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2438)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2438)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2438
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.161"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..306
                     /locus_tag="ACG8LA_002928"
     CDS             <1..306
                     /locus_tag="ACG8LA_002928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HFQ0205170.1"
                     /translation="RLGKKGQEVAEDDPYWEIEASYIAQCAYNTTLMFSPDVIIFGGG
                     VMKQRHMLQNVHDAFAKLVNGYVETPELSKYIVTPALEDNAGTLGCLALAREAVLHS"
     gene            complement(541..1922)
                     /locus_tag="ACG8LA_002929"
                     /pseudo
     CDS             complement(541..1922)
                     /locus_tag="ACG8LA_002929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010726506.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT          704 a          429 c          441 g          864 t
ORIGIN      
        1 cgcttaggga aaaaaggaca agaggttgca gaagatgatc cttattggga aatcgaagcc
       61 tcctatattg ctcaatgtgc ctacaataca accttgatgt tttctccaga tgtgatcatt
      121 tttggcggtg gtgtgatgaa acaacgccat atgctgcaaa atgtccacga cgcatttgca
      181 aaattggtca atgggtatgt cgaaacacct gagttaagca aatatatcgt gaccccagca
      241 ttagaagaca acgctggaac gctcggttgt ttggcattgg ctcgagaagc ggtcttacat
      301 tcataaacga aaaaaggctc ttcgacattt agtgttggta gagaaagata caactgaaaa
      361 tctagtcata accagttagg cagagtgctt aactggtttt tgttttactt ggaagatcaa
      421 gccttgaatg agataaattc ttgctcgaaa gttatggaaa tttcgatagc cgtaggccac
      481 ttgtattgtg caatagtttt ttacaaaaaa aagggggtgc ggatattttt ttggaccttt
      541 ttaacaaata tatctttgct tcttccgata ttgaagaggg cttagccctc ctaaagataa
      601 cttaattcgt tgattattat accaatgaat ataatcatcc aatttgttta taaactgatt
      661 gattgttgta ttcttccagt cacgttgata aaacatctcg ttttttaatc gtccaaagaa
      721 accttcgcac gctgaattat ctggtgaata acccttttta gacatagagt gaagcaagtt
      781 ggctttgttc caatagtcca actaacaata gcaccatcgt aacaatcgac aagtggtgat
      841 aagtagattt tccctgcggg aattctaaat tcagtaatat ctgttaacca tttttcattt
      901 ggcttctttg ctttaaaatt ccgatttaat aaattggggt gtgcaggaga aatttcccca
      961 gcatacgaag aatacttttt tcgtctagaa aatttaacaa atagattttc ctcagtcatc
     1021 aatctacgta caactttttc agaaagcttt ttacccatat tttttaaagc ttggtgaatt
     1081 ctacggtaac catacgcaca gaagttatga ttgaaaatcg tgataattaa ttgacgttct
     1141 ttgtaatact tatctggttt ctcaagtgct tgtttttgat aaaaatagct gcttttaggc
     1201 aactggagct gttgaagaag ctctttcaag gtgaactgat ttcgtaaggc atcaatcaat
     1261 atcgtttttt cttgatttga tagacaaaga agattgacgc ctttttcttt ttttagcagt
     1321 tcagccgctc cttcgagtaa tgctttttcg agctgtaatt ggtgtacttg tttttgtaag
     1381 tcttctactt cctttaaaag tagctctttt tgtttttcct gattttttaa agtcatacgc
     1441 aatggaaaat cctttccaag aaccgtgttt ttccattgat atagagtaac tctactaatt
     1501 ccttcagatt cggctaaatt tttcctatta gtttgcggtt tatagaattt tttcaacaca
     1561 gcttcttttt gatcttgtgt taactttacc gcactttttc ggagttttct agctcctggt
     1621 gcaagttctt cacaccactg ccgcaaggac tctctattag gataaccaag catgcgaatg
     1681 gttcgtgcat aacattgacc atattcaaaa taatgattca ccgctattcg tttttgttct
     1741 tcagaatact ttgatttttt tcggtgctcc tgatggagct ctccggattc caaatactct
     1801 ttataccatt tccgtagtgc accaatcgac ggatacccta attctcgaat ggttgcagca
     1861 taagagcaat cgtattttaa aaataactga attgccctta cacgctcttt gtgggaaaac
     1921 acacggacat tcctcctaag tttatttttt cgtccaggat tatgtccgca cccccttgct
     1981 ttctgatgac ttattctggt tctttgagtg tcaatgcata gatgtgatgt agctagttag
     2041 aaaaaaattt tgaatactct ttttttcttt cagactcctt tttaagtaag attttgaagt
     2101 gtgagttacg gggtcagaaa cttaaaagtt tttgttcctt tattttcaag tctgatttgg
     2161 cagcttttcg gcagctcatt tatttatggt cagaaataga tgctgaaatt ttaatctatt
     2221 agcaaatagt ccagaacgta tgaagaggag tcggatatca tttgtcatta acaccataaa
     2281 tatttataaa attcgtgttc acctacaatt aaatttaata tataatattc gttgtaaggg
     2341 cttataattt tttgttaatg aacaagatag gaagaaacat ttaatggaca gttttcagag
     2401 attgtcacta tatgatttgt caaattaagc tagaataa
//
LOCUS       DAZKKZ010000152         2401 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.162, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000152 DAZKKZ010000000
VERSION     DAZKKZ010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2401)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2401)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2401
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.162"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            208..2070
                     /locus_tag="ACG8LA_002930"
     CDS             208..2070
                     /locus_tag="ACG8LA_002930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HFQ0205171.1"
                     /translation="MQQLTKRERQLLIYLVEMSEPVTIKKLAEKENVSVRTIKYDLDD
                     IREWLNERKQVLYSKRSQGIWMNISSSDRIKLKSELMDVNRFEIFADQSLRIKRLLIM
                     LLVTKEAITGMKMANALDVSKDTIMNDLDVLENNFLKEGLTLNRQARKGFWIIGEERL
                     VRLTIEEILQKEFTDYDIYKLMSLLLNGGETEYFEMYSATATPIQEVFNQVIIRMRHL
                     LEFENLEKLNYAELLNILIRVTIATVRLRKEATIGRYQLVAEQELDKNDLSYRVMQQV
                     FDYYQLPLFEDEYHYIYSDTFDTIHQQDVMKLVENVIYKVSKAINHSFYQDPQLLTNL
                     YAHLSMRLSRKKKFVNEYNPFKEDIKQKYPELFDAIKQAVRQEISEQNILINDSFVAY
                     IALHFLVSYEREEDLRSVRAVYICSTGLGVTSLIKQKINEELNNITIVAFASVLNAQE
                     MIATKDPDLVISIFPINGIDRPFIKVHPLPTEQDLKKIQQIIKKILASSNQQERHNLN
                     LRETSINKDTLEDFSKELILKAYTIYERLLVILEAELIQEYREAFLLHVFLMVHRITF
                     DQQYMAEGRQVDQIILDKGTLVGKIEAVFAENNLGINQSEISALFSYIKEGASS"
     gene            2070..>2401
                     /locus_tag="ACG8LA_002931"
     CDS             2070..>2401
                     /locus_tag="ACG8LA_002931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HFQ0205172.1"
                     /translation="MKMSDEALKIIEESQNREKLKQVIDLIEERLVEHAIVPTELQWT
                     ILINHLNEMLKRSQRKETIPVVDRDLFKEVSKEAITISDEIVRSIGNLTDDEIYVLSI
                     HFETAKNN"
BASE COUNT          867 a          353 c          466 g          715 t
ORIGIN      
        1 aaaaaatttg aaaaagcgtt tgattattta tattacgact tagtgcaata aaaaacgctt
       61 tttaacagta catgtagtcg tctttataat agataaactc tgtaatatta gttaaaaagc
      121 tataagttgc acttagttaa gtgcaaacat ttcatattgt cgttagttta gaaaacgctt
      181 atattagcaa tgtaaggaga gatgataatg cagcagctaa caaaaagaga aaggcagctt
      241 ttgatttact tggtggaaat gtctgaaccg gtaacaatca aaaagttggc tgaaaaagaa
      301 aatgttagtg ttcggacgat aaaatacgat ctagatgata taagagagtg gctgaatgag
      361 cggaagcaag tcctatatag caaacgtagt cagggaattt ggatgaatat tagtagctct
      421 gatcgaatca aattaaaaag cgaattgatg gatgttaatc gttttgaaat atttgcagat
      481 caaagtctcc gaatcaaacg tttactaatt atgcttttag taacaaaaga agctattact
      541 ggaatgaaaa tggccaacgc attagatgtc agcaaagata cgatcatgaa tgatttagat
      601 gtgctggaaa ataattttct taaggaagga ttgaccttga atcgtcaggc gcgaaagggt
      661 ttttggatca taggagaaga acgtctagtt cgattaacga ttgaagagat tcttcaaaaa
      721 gagttcacgg attatgacat ttataaatta atgtcattgt tattgaatgg cggtgagact
      781 gaatactttg aaatgtattc tgctactgct acacctatcc aagaggtatt taatcaagta
      841 atcattcgaa tgcgacactt actggaattt gaaaatctag agaaactgaa ttacgcggaa
      901 ttactaaata ttctgattcg agtgacaatt gctaccgttc gcttacgcaa agaggctacg
      961 attggtcgtt atcaattggt tgctgaacaa gaattagaca aaaacgatct ttcttatcgc
     1021 gtcatgcagc aggtctttga ttattatcag ttgccactgt tcgaggatga atatcattat
     1081 atctatagtg atacattcga cacgattcac cagcaagacg tcatgaaact agttgagaat
     1141 gtgatttata aagtaagtaa agcaatcaac cattcttttt atcaagatcc acaattgttg
     1201 acgaatctgt atgctcattt atccatgcga ttatcgagaa agaaaaaatt tgtcaatgaa
     1261 tataatcctt ttaaagaaga tatcaagcag aaatacccgg aattatttga tgcgatcaag
     1321 caagcagttc gacaagaaat aagtgaacaa aatattctga tcaatgattc tttcgtggca
     1381 tatattgcct tacacttttt ggtttcctac gaaagagaag aagatctacg aagcgttaga
     1441 gccgtctaca tttgttcaac agggttgggt gtgactagtc tgatcaagca aaagatcaat
     1501 gaagaattaa ataatatcac tatcgtggca tttgcttcag tattgaatgc gcaagaaatg
     1561 attgctacca aagatcctga tttggtgatt agtatttttc caattaatgg catcgatcgt
     1621 cctttcatca aagtccatcc attacccact gaacaggact tgaaaaaaat tcaacaaata
     1681 ataaaaaaaa tacttgcttc ttccaatcag caggaaaggc ataacttgaa tcttagagaa
     1741 acgtccatca ataaagatac tttagaagac tttagcaagg aattgatttt gaaagcttat
     1801 acgatttatg aacgtttact tgtcattttg gaagcagaat tgatccaaga atatcgagaa
     1861 gcttttttgc ttcatgtatt cttaatggtt catcgtatca catttgatca acaatatatg
     1921 gcagaaggtc gtcaagtaga ccagattatt ttagacaaag gaacactggt aggaaaaatc
     1981 gaagcagttt ttgcagaaaa taatttagga atcaatcagt cagaaatcag tgcattattc
     2041 tcatatataa aagaaggagc gtcaagttag tgaaaatgtc agacgaggct ttaaaaatta
     2101 tcgaggaaag tcaaaatcgg gaaaagttaa aacaagtgat tgatctaatt gaagagcgat
     2161 tagtagaaca tgctattgta ccaaccgagt tgcagtggac cattctaatt aatcacttga
     2221 atgagatgct gaaacgttct caaagaaagg aaacgattcc cgtagtcgat cgggatttgt
     2281 tcaaagaagt atccaaagaa gccataacta tttctgatga aatagttaga agtatcggta
     2341 atttaaccga tgatgaaata tatgttttgt cgattcattt tgaaacagca aaaaataatt
     2401 a
//
LOCUS       DAZKKZ010000153         2395 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.163, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000153 DAZKKZ010000000
VERSION     DAZKKZ010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2395)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2395)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2395
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.163"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..453
                     /locus_tag="ACG8LA_002932"
     CDS             <1..453
                     /locus_tag="ACG8LA_002932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFQ0205173.1"
                     /translation="YRNNYSAFKSMGGGVELDCIHELDYIINLFGFPKSVKKQFGKYS
                     NLEINSNDLATYILRYDDKIIEIHLDYFGRVPTRKFQLFTLDECINVDLLNNKISFEE
                     NIVKEMPESANDMYEKELKYFFENVVTGKENWNDLYHANEVLKIAEEK"
     gene            454..1206
                     /locus_tag="ACG8LA_002933"
     CDS             454..1206
                     /locus_tag="ACG8LA_002933"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acylneuraminate cytidylyltransferase family
                     protein"
                     /protein_id="HFQ0205174.1"
                     /translation="MEILFTICGRAGSKGFKNKNLKYLAGKPLVHFALAMIDIYQQKH
                     PEHNCTTCLNTDSNELVELTTKLNPSVKIVERKPELATDTVGKIEVIRDSFLQLERED
                     NIFDLIIDLDLTSPLREVSNLEELIDEHLKNLDKDVYFSVVSARRNPYFNMVKRIENE
                     VTIVNKSRYTSRQQTPEVFEMNASMYSFKPEFLKKSNYIFDGQCGIIKMRDYLILDID
                     SEEDFKWLEFLFPKFLEDSSELQDIYNYLYRR"
     gene            1211..2158
                     /locus_tag="ACG8LA_002934"
     CDS             1211..2158
                     /locus_tag="ACG8LA_002934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HFQ0205175.1"
                     /translation="MSCYLITGGAGFIGSTLANHLGEEHVVIVVDDLSMGKVENLDMT
                     KNITFIEGDVAEKSLMEEIMKANKFDYIFHLAAVASVADSVARPVETHRVNFESVLMI
                     LELIRKYQPDLKRIVFSSSAAVYGDEPTLPKKEESVIRPLTPYAVDKFAAEQYVLDYC
                     HLYDVPGSAVRFFNVYGPNQNPNSPYSGVISILVDRYKKQIVGEATSFTLFGDGSQSR
                     DFVYIDDVIQALLLVANEEAALGKQFNVGTGKATTLLELIHAINEILGVELTLEYKEE
                     RSGDIHDSLADITKIQSIGYQPKYGILSGMTNYLKTEIN"
BASE COUNT          847 a          306 c          466 g          776 t
ORIGIN      
        1 tatagaaata attattctgc ctttaaatct atggggggag gagtagaatt agactgtata
       61 catgaattgg attatattat aaacctattt ggtttcccta aatcagtaaa aaaacagttt
      121 ggtaaatatt cgaatcttga aattaacagt aatgatttag caacatatat attgagatac
      181 gatgataaaa ttatagaaat tcatttagat tattttggaa gagttcctac aagaaaattt
      241 caattgttta ctttagatga atgtatcaat gttgacttat taaataataa aataagtttt
      301 gaagaaaaca ttgttaaaga aatgcctgaa tctgctaatg atatgtatga gaaggagttg
      361 aaatatttct ttgaaaacgt agtaacaggc aaagaaaact ggaatgattt atatcatgca
      421 aacgaagtat tgaaaatagc tgaggagaaa taaatggaaa ttttatttac tatttgtggt
      481 agagctgggt ctaaggggtt taaaaataaa aatttgaaat atttggcagg aaagccccta
      541 gtccatttcg ctttagcaat gatagatatc tatcaacaaa aacatcctga acataattgc
      601 acgacttgtt tgaatacgga cagtaatgag ttagtagaat tgacgactaa gttaaatccg
      661 tctgtgaaaa ttgtagaacg taaacctgaa ttagctacag atactgtagg gaaaattgaa
      721 gtgatacgtg attcattctt acaactagaa agagaagata atatatttga tttaattata
      781 gatttagatt tgacttcacc tttacgtgaa gtttctaatc ttgaagaatt aatagatgaa
      841 catctaaaaa atttagataa agacgtctac ttttcagttg tttctgcaag acgtaatccc
      901 tattttaata tggtaaaaag aattgaaaat gaagttacta tagttaataa atcaagatac
      961 acatctaggc aacagacacc tgaagttttt gaaatgaatg cctcaatgta ttcttttaaa
     1021 cctgaatttc taaaaaaaag taattatatt tttgatgggc aatgtgggat aataaaaatg
     1081 agagattatc taattttaga tattgatagt gaagaagatt ttaaatggtt agaatttttg
     1141 tttcctaaat ttttagaaga ttcttcggag cttcaagata tctataatta tttatatcgg
     1201 aggtaaaagg atgagctgtt atcttatcac cggtggggct ggcttcattg gttctacctt
     1261 agccaatcat ttaggagaag aacatgtggt aatcgtcgtc gatgacttat caatgggaaa
     1321 agtagaaaat cttgatatga cgaaaaatat cacttttatt gagggagatg tcgctgagaa
     1381 atccttgatg gaagagatca tgaaagctaa taaatttgat tatatctttc atttagcagc
     1441 agttgctagt gtggcagatt cagttgcccg accagtagaa acacatcgtg tgaattttga
     1501 aagtgtatta atgattttag aattgatccg caagtatcaa cctgatttaa aacggatcgt
     1561 gtttagttct tcagcggctg tttatgggga tgaaccgact ttaccaaaaa aagaagagtc
     1621 cgtgattcgc ccattgacgc cttatgcggt tgataaattc gctgcagaac aatatgtgct
     1681 agattattgt catttatatg atgtacccgg tagcgcagtt cgttttttca atgtctatgg
     1741 tccaaatcaa aatccgaatt ctccatacag tggtgtgatt tctattctcg tagatcgcta
     1801 taagaaacaa atcgtaggag aagcaacttc atttacatta tttggtgatg gaagccagtc
     1861 tagagacttt gtttatatag atgatgtaat ccaagcatta cttttagttg cgaatgagga
     1921 agctgcactg gggaaacaat tcaatgttgg aacgggtaaa gcaaccacac ttttggaatt
     1981 gattcatgca atcaatgaaa ttctcggtgt agaattgaca cttgaataca aagaagagcg
     2041 ttcgggtgat atccatgact ctctagcaga tattactaag atccagtcaa ttggctatca
     2101 accgaaatat ggtattttaa gtggaatgac taattatttg aaaactgaaa tcaattaaaa
     2161 catactaaga taagattaga gggtaaattc aggctctttg tcaataagga ctgatgagtt
     2221 ttgtaaaatc aaatctggga tagaagggct ctttgtcaaa tgatgttggt aaagagaaat
     2281 cttagaataa tttggacaga acagaaagaa gaaaacctct ttctgttctg tttatttggt
     2341 taaaaatgtt ttgccatgac gaatcataat tcgtagtttg aaattgtaaa agttg
//
LOCUS       DAZKKZ010000154         2385 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.164, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000154 DAZKKZ010000000
VERSION     DAZKKZ010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2385)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2385)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2385
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.164"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..1012
                     /locus_tag="ACG8LA_002935"
     CDS             <1..1012
                     /locus_tag="ACG8LA_002935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013727023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HFQ0205176.1"
                     /translation="NAEVLEATHDIKTVVMDKTGTITVGKPQVTDIISIGRISENEIL
                     RIAAGLEDSSEHPLALAVINEAKDKKITPAVAKNFTAISGKGVQALIDGKQAFIGNDR
                     LSDDFNMTDDLKIKMTSLQAQAKTVVLVGYDGQIIALIGIQDAPKSSSKAAIRAMQKS
                     GFHTVMLTGDNRLVAQAIADDIGIDEVIADVMPGDKAQHIRKLQEKGAVAFVGDGIND
                     APALSTATVGIAMGSGSDIAIESGGIVLVKNDLMDVVTSLVLARKTYSRILINLFWAF
                     IYNVIGIPVAAGIFSALGFTLSPELAGLAMALSSITVVLSSLLLNYVRLPKNSETLIG
                     NS"
     gene            1292..1915
                     /locus_tag="ACG8LA_002936"
     CDS             1292..1915
                     /locus_tag="ACG8LA_002936"
                     /inference="COORDINATES: protein motif:HMM:NF026041.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HFQ0205177.1"
                     /translation="MYHCTRKLLGLTDENLFFEEEWLETVEEDGFRTNLIHDKLSYIL
                     SHCRKCGIKNEGQIIKNGSHKTKVQLLPYRATKTELRLVRTRFYCKECQSTFNAQTNL
                     VDENCYLSKELKVQIALELAKNTIKKEIANRCFVSDVIVLRVLHTCLKTYHPRFDTLP
                     SVLCFDEYKSMKSCSGKNEFCFYEWADPAINRCIGESSPYFLKTIFP"
     gene            1839..2120
                     /locus_tag="ACG8LA_002937"
     CDS             1839..2120
                     /locus_tag="ACG8LA_002937"
                     /inference="COORDINATES: protein motif:HMM:NF013753.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFQ0205178.1"
                     /translation="MNGQTQQLIGVLENRRLTFLKPYFLNFTRKARANVKYVVMDMNA
                     PYFELVKAVFPNAKIVTDRFHIVQQITRTLNQLRIKTMNRFQKTEPTKY"
     gene            2124..2285
                     /locus_tag="ACG8LA_002938"
     CDS             2124..2285
                     /locus_tag="ACG8LA_002938"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0205179.1"
                     /translation="MKRFWKLLLTHAYDLDSSDYQYDRSFRRPMTQKAMVDELLSYDE
                     QLTRAYETC"
BASE COUNT          781 a          426 c          480 g          698 t
ORIGIN      
        1 aaatgctgag gttcttgaag cgacccacga tataaaaacc gtcgtcatgg ataagactgg
       61 aacaattact gttggcaaac cacaagtgac cgatattatc tctatcggaa gaattagtga
      121 gaacgagatt ctgcgaatcg ctgctggact tgaggattca tcagaacacc cattagcttt
      181 agcagtaatt aatgaagcaa aggacaagaa aattactcct gccgtagcta aaaatttcac
      241 tgctatttct ggtaaagggg tacaagcttt gattgatggt aagcaggctt ttattggtaa
      301 tgatcgttta tccgatgact ttaacatgac agatgatctt aagattaaaa tgacatcttt
      361 acaggcgcag gcgaaaactg tggtattagt tggttacgat ggtcaaataa ttgctttaat
      421 tgggattcaa gatgcaccta agtccagctc taaagctgct atcagggcaa tgcaaaaatc
      481 aggatttcac actgtgatgc taactgggga caatcgtttg gtcgcacaag ccatagcaga
      541 tgatattggg attgacgagg tcatagcaga tgttatgcct ggggacaaag cacaacatat
      601 tagaaagttg caagaaaaag gagcagtcgc ctttgtaggt gatggaatca atgatgcccc
      661 tgcattatcc acggcaacag taggtattgc tatgggatcg gggagtgata ttgcaattga
      721 atctggaggt attgtactag tcaaaaatga tttgatggat gttgtaactt ctttagtatt
      781 agcacgaaaa acatatagtc ggattttgat taacttattt tgggctttca tatataacgt
      841 gataggtatt ccagtcgcag cgggtatatt ctcagcactt ggatttacac tatctccaga
      901 gttagctggt cttgcaatgg cacttagctc aattactgtt gttttgagct cactattatt
      961 gaactatgtg cgcttgccaa aaaatagtga gacacttata ggtaatagtt agtatttgta
     1021 atatacaaaa gtgacgcttt taattataat agtaattttc ctttttcaaa atttgaatca
     1081 gagtcttaaa tactaggcat acaataagag aaccaaaaat cagaactact ggatgtagtt
     1141 ctgatttttg attctacaat atttagtgtt ggtggaaaat ctacagattt tctactgaca
     1201 ctttttttgt aaaaaaagat agaaaaagag atagcctaac tggtggaatt tagtcgtcta
     1261 aaacaaaacc ataccaagaa aggatatctc catgtatcat tgtactagaa aattgttagg
     1321 tttaacagat gaaaatttat tcttcgaaga agaatggtta gagacagtag aagaagatgg
     1381 ttttcgcacc aatcttatcc atgataaact tagctatata ctaagccatt gccgtaaatg
     1441 tggcatcaaa aatgaaggac aaatcatcaa gaatggctca cataaaacaa aagtccaact
     1501 tttgccttac cgagcaacca aaacagaatt acgcttggta cgtacgcgct tttactgtaa
     1561 agaatgtcag tcgacattca acgctcagac caatttggta gatgaaaact gctatctctc
     1621 aaaggaatta aaggtacaaa ttgccttgga actagcgaag aatacaataa aaaaagaaat
     1681 tgccaatcgc tgttttgtat cagacgtaat cgttttgcgt gtcctgcaca cctgtttaaa
     1741 aacgtatcat cctcgttttg atacgttacc ttcggtcctt tgttttgatg agtacaaatc
     1801 gatgaagtcc tgcagtggaa aaaatgagtt ttgtttttat gaatgggcag acccagcaat
     1861 taatcggtgt attggagaat cgtcgcctta ctttcttaaa accatatttc cttaatttca
     1921 ctcgaaaagc acgagcgaac gtaaaatacg tcgtgatgga tatgaatgcc ccttattttg
     1981 aacttgtaaa agcggtcttc ccaaacgcca aaatcgtgac cgatcgcttt cacattgtcc
     2041 aacaaatcac tcgtacgtta aatcagttgc gaatcaaaac aatgaacagg tttcaaaaaa
     2101 cggaaccgac aaagtattga cgattgaagc gattctggaa attactcctt acgcatgcct
     2161 atgatctgga tagttctgat tatcaatatg atcgatcctt tcgcagacca atgacgcaaa
     2221 aagcgatggt cgatgagctt ttgagttacg atgagcaatt aaccagggct tacgagactt
     2281 gctagctcct cctctatcac tttaaacaca aggacaacca aagttttttc gatacgatca
     2341 acagcttaga tcaatgcctt ccacaatggt tttgtaagaa gctga
//
LOCUS       DAZKKZ010000155         2347 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.165, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000155 DAZKKZ010000000
VERSION     DAZKKZ010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2347)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2347)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2347
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.165"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..383)
                     /locus_tag="ACG8LA_002939"
     CDS             complement(<1..383)
                     /locus_tag="ACG8LA_002939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0205180.1"
                     /translation="MNFLVVLKDTLIERFTFLYVQLQENKTLLHFSPEFHLEGLTLGE
                     IYQAEGLSAVLHFFKVELELPVKDYIELSLESWDRAVVELFPEGLMIDTNDGKIHLTA
                     AELQKQMRYQIDDENSFSIFRRQQK"
     gene            complement(568..966)
                     /locus_tag="ACG8LA_002940"
     CDS             complement(568..966)
                     /locus_tag="ACG8LA_002940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030234 - enzyme regulator activity
                     [Evidence IEA];
                     GO_process: GO:0006808 - regulation of nitrogen
                     utilization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="P-II family nitrogen regulator"
                     /protein_id="HFQ0205181.1"
                     /translation="MKDLVALNLHMIVTIVDGGMGEDVIDFSKEAGAAGGTILHGRGS
                     GVHDSGKFLGLDISPEKDIVLTLVPDSLTNKVMDAIGQGINIDIPGNGICFSIDVDKV
                     IGITKIHQYREIIGMQELLDENNDREKSES"
     gene            complement(963..1736)
                     /locus_tag="ACG8LA_002941"
     CDS             complement(963..1736)
                     /locus_tag="ACG8LA_002941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HFQ0205182.1"
                     /translation="MSFWQQVIDGIEIVTMEVILAVAPIVILFVLMNIISFRMRKKRF
                     FDIMKGFLITTIGLILFLHGVNMAYVPVGQHLGSAIAGLPYNYILVPLGFLMGFLVGF
                     AEPAIHVMIKQVEELSEGRIRSKIMLMVISIGIGAAVGLSMWRLLVGFSLYYFLIPGY
                     GLAFILGRKVDKIFLAMAFDNGGVATGPMCSTFILSMSVAIAAQIEGRDPIIDGFGVV
                     AMIALTPILSTLVLGYIYKRKDEKDRIEKERLQKLGESK"
     gene            complement(1733..>2347)
                     /locus_tag="ACG8LA_002942"
     CDS             complement(1733..>2347)
                     /locus_tag="ACG8LA_002942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HFQ0205183.1"
                     /translation="FVFAPLEGEDLASFLVGAAIMMIGMTLFLFGADYSMMEVGDLVG
                     KYMIKKKSLTVLVSLGFAIGIVITIAEPSVQVLGQQVYDISDGEIGRVLLIGIVSVGT
                     GVFLAFALLRVVFKLSYYQLMAIGYIGVLIASFFTSSEFMPIAFDSGGVTTGPVTVPF
                     ILALAGGMTSMIKQKKNENDSFGMVGIASLGPILAVMILGVIFQ"
BASE COUNT          740 a          563 c          358 g          686 t
ORIGIN      
        1 atcttttgct gacgtctaaa aatagaaaaa gaattttcgt catctatttg ataacgcatt
       61 tgtttttgca gttctgctgc agtcagatgg atcttcccat cgtttgtatc gatcattaaa
      121 ccttctggaa acagttcaac cactgctcga tcccaagatt caagagaaag ctcgatataa
      181 tcttttactg gtaattccaa ttctacctta aaaaagtgca aaacagccga cagcccttct
      241 gcttgataga tttctcctaa tgttagcccc tctagatgga actctggtga aaaatgcagc
      301 aatgttttat tttcctgcaa ttgaacatat agaaatgtaa atcgctcaat cagagtatct
      361 tttaaaacaa ctaaaaaatt catttttctc cccctttttt catcattttt aaaatagcat
      421 attttgaaaa gaaagtctga tgcttagagt agaatttcat aaaaatttac tatttcataa
      481 gtattcacga gaaaaataca aacaaaaaag cggaaataac gctcatccgc cttcttgttt
      541 gtgtttattt cctcttcaaa cgcttgtcta tgattcagac ttttctctat cgttattttc
      601 atctaaaagt tcttgcattc cgataatttc tcgatattga tgaatcttag tgataccaat
      661 gactttgtct acatcaatac taaaacaaat accattacct ggaatatcga tgttgatgcc
      721 ttgaccaatc gcatccatta ctttattcgt caaactatcg ggtactaatg tcaacacaat
      781 atctttttct ggcgaaatgt ccaaacctaa aaatttccct gaatcatgta caccagaacc
      841 tcttccatgt aagatcgttc cgcctgctgc acctgcttct tttgaaaagt cgataacatc
      901 ttcgcccatt cctccgtcaa cgatcgtcac aatcatgtga agattcaatg ctacaagatc
      961 tttcatttgc tttcccccaa tttttgcaat ctttcttttt cgattctgtc tttttcatct
     1021 tttcgtttat aaatatatcc tagtactaaa gtggataata ttggtgtcaa tgcaatcatt
     1081 gcaaccacac caaacccgtc aatgatcgga tctcttcctt caatttgtgc agcgattgcc
     1141 acgctcattg ataaaataaa tgtcgaacac atcgggcccg ttgctactcc accgttatca
     1201 aaagccattg ctaaaaagat cttgtccact tttcgtccta aaataaatgc tagcccgtat
     1261 cctgggatca agaaataata aagagagaat ccgacgagca aacgccacat agacaatcct
     1321 actgctgcgc cgatcccaat tgaaattacc atcagcatga ttttcgatcg gattctcccc
     1381 tcgctcaatt cttcaacctg tttgatcatt acatgaatcg ccggctcagc aaaccctact
     1441 aagaacccca ttaaaaagcc aaggggaacc agtatataat tgtaaggcaa tcccgcaata
     1501 gcactgccta aatgctgtcc taccggtaca taagccatat tgactccgtg caggaaaagg
     1561 atcaacccaa tagtcgttat caagaaacct ttcataatgt caaagaaacg ctttttgcgc
     1621 atacgaaaac taatgatatt cattaaaaca aataggatta cgataggtgc cactgccaaa
     1681 atgacttcca tggtaacgat ttcgattcca tctatcactt gctgccagaa actcattgga
     1741 agatcacccc caaaatcatc acggcaagaa tcggccctaa cgaagcaata ccgaccattc
     1801 caaaactgtc attttcattt ttcttttgtt tgatcatact agtcatccct ccggcaaggg
     1861 ccaagataaa tggaacagtt actggaccag tagtcactcc ccccgaatca aaagcaatcg
     1921 gcataaattc ggaactggtg aaaaatgagg cgatcaaaac gcctatgtag cctatagcca
     1981 tcaattgata ataggatagc ttgaatacga cccgaagcag cgcaaaggct agaaatactc
     2041 cagtgccgac gctgacgatc ccaatcagca acactctgcc aatctctccg tcagatatat
     2101 catatacttg ttgtcccaaa acttgcacgg aaggttcagc aatcgtgatc acgatcccga
     2161 tagcaaatcc caaactgacc aaaacggtca aacttttctt tttgatcata tatttcccta
     2221 ctagatctcc gacttccatc atagaataat ctgctccaaa caaaaagagc gtcattccga
     2281 tcatcatgat tgccgcacca accagaaatg aagcgaggtc ttctccttct aacggtgcaa
     2341 aaacaaa
//
LOCUS       DAZKKZ010000156         2316 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.166, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000156 DAZKKZ010000000
VERSION     DAZKKZ010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2316)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2316)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2316
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.166"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            288..542
                     /locus_tag="ACG8LA_002943"
                     /pseudo
     CDS             288..542
                     /locus_tag="ACG8LA_002943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002405927.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
     gene            612..1124
                     /locus_tag="ACG8LA_002944"
     CDS             612..1124
                     /locus_tag="ACG8LA_002944"
                     /inference="COORDINATES: protein motif:HMM:NF013677.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFQ0205184.1"
                     /translation="MTNKNNERYSTELKATAIKKMMPPENRGIRQLSQTLGIPEATLY
                     SWRKKARIQGNTTPGTKKNVEKWSSEDKFLIVMESFSMNQVELAEYCRKKGLFKEQIE
                     AWKKTCLSANEQEENRTRELATELKEEKKQARQLEKELRHKEKALAEAAALLLLRKKA
                     HAIWGDQEEE"
     gene            1121..2158
                     /locus_tag="ACG8LA_002945"
     CDS             1121..2158
                     /locus_tag="ACG8LA_002945"
                     /inference="COORDINATES: protein motif:HMM:NF033516.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HFQ0205185.1"
                     /translation="MISSSDRKQAVELIQEANRNGARLTYACNELNISVRTYERWTRE
                     GTIAHDQRPLAKRPVPKNKLTDQEREKIIETVSKKEFMNLPPSQIVPKLADCSIYIAS
                     ESSFYRVLREKNMQHHRGRSQVSQKRIPPSHLATKPNEVWTWDITWLKGPIKGLFYRL
                     YLIIDLFSRKMVGWEIWESEEARHAEKLIKQTVLKERIQGQPLVLHSDNGSPMKAATF
                     QVLLEKLGIQSSYSRPRVSNDNPYSEAAFRTLKYRPEYPNNGFKTIDDARKWTKEFVD
                     WYNDSHLHSGIQFVSPAACHEGRHLAILEKRKQVYEDAKKRHPERWSKGVRNWTPHQS
                     VALNPLKETES"
BASE COUNT          842 a          419 c          465 g          590 t
ORIGIN      
        1 ataaattatc taaagagaat taagttttga ttatgtaata agttttggta ctaaaaaaga
       61 cttgatctaa ttagaccaag tcttttgtta gtgttatatt aataacaaaa taaaaataag
      121 aagtcgctca ctccccgacc aaagtttgtg agcaaaataa acagtcgatg tttgtttctt
      181 aattgtatat cttgatatta aacgatttaa gattattctt caagatatat attcgcaaat
      241 gtaattggaa aagcgacttc ttaaacaaaa ttaaggagtc gctttttatg gcaaaaataa
      301 cgaaaaatga gcaagaaaat ttggtggaaa attacacaaa aaaaccggcg tactctaata
      361 gccggttaga cgcacatttc gtgtgcactt ctaatccgaa attgagcttt gacgctatga
      421 cgatagtcgg aaaccttaat aaaaacagcg ctaaaaagct atccgatttt atgagtttag
      481 atccacaaat tagactttgg gatatacttc aaacaaaatt taaagctaaa gcactacaag
      541 accccctatg ttaggctagt tgtcgtatag gataataagt tataataaag actatacgga
      601 ggatgattac catgacaaat aaaaacaatg aacgttactc taccgaactg aaagcgacag
      661 ccatcaagaa aatgatgcca cccgaaaata gggggattcg ccaattaagt caaactttgg
      721 gcattccaga agcgactctt tattcttggc gtaaaaaagc tagaattcaa gggaatacta
      781 cacccggaac gaaaaaaaat gtcgaaaaat ggtcaagtga agataaattt ttaattgtga
      841 tggaatcatt ctcaatgaac caagtagaac ttgcggaata ttgccgaaag aagggcttat
      901 ttaaagaaca aattgaggct tggaagaaaa cgtgcttatc tgcgaatgaa caggaagaaa
      961 atcgaacgag agaacttgca actgaactaa aagaagagaa aaaacaagcg cgtcaattag
     1021 agaaagaatt acgtcataag gaaaaagcat tagcggaagc cgctgctctc ttattactaa
     1081 gaaaaaaagc acacgcgatt tggggggacc aagaggaaga atgatttcat cttcagatcg
     1141 caaacaagct gttgaactta ttcaagaagc caatcgcaat ggggcccgtc tcacctatgc
     1201 ctgtaatgag ctgaatatta gcgttcgaac ctacgaacga tggacgcgtg aaggtacgat
     1261 agcgcatgat caacgccctt tggcgaaacg tcctgtaccc aaaaataaac tgacggatca
     1321 agaacgcgaa aaaataatag aaaccgtttc aaaaaaagaa tttatgaatt tgccacctag
     1381 ccaaattgta ccaaaacttg cggattgctc gatttatatt gcatcagagt ctagcttcta
     1441 tcgtgtattg cgagaaaaaa atatgcaaca tcaccgtggc cgaagtcaag tttcacaaaa
     1501 acgcataccg ccaagtcacc ttgcgacgaa gccaaatgaa gtttggactt gggatattac
     1561 ttggctaaaa ggtccaataa aaggactctt ttaccggtta tatctcatca ttgatttatt
     1621 tagccgtaaa atggtaggct gggagatttg ggaatcagaa gaagctcgtc atgccgaaaa
     1681 acttattaaa cagacggtgc ttaaggaacg tatccaagga cagccgttgg ttttacactc
     1741 cgataatggc agccctatga aagccgcgac ttttcaagtc ttactcgaaa aattaggaat
     1801 tcaaagttct tattcaagac cacgagtgag taatgacaat ccttattcgg aagcggcttt
     1861 ccgaacgtta aaatatcgac cagaatatcc caataacggc tttaaaacaa tagatgatgc
     1921 tcgaaaatgg acgaaagagt ttgtcgattg gtataacgat tctcatttgc atagtgggat
     1981 tcaatttgtg tctcctgcag cgtgtcatga aggacgacat ctcgctattt tagagaaacg
     2041 aaagcaggtt tacgaggacg ctaaaaagcg ccatcctgaa cgctggtcaa aaggtgttcg
     2101 aaattggact ccacatcaat cggtggcgtt gaatccttta aaagaaacag aaagttaaca
     2161 ggagcataat ctttcaagat tatcaaataa ccctcgtcac ccaatagggg aaaaagttat
     2221 tcttccccta ttggataacg aggccaaccg accataggga ggttctgctt tttgataggt
     2281 ggaaaataaa aatacgacaa ctatattgac aaacac
//
LOCUS       DAZKKZ010000157         2312 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.167, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000157 DAZKKZ010000000
VERSION     DAZKKZ010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2312)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2312)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2312
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.167"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(76..147)
                     /locus_tag="ACG8LA_002946"
     tRNA            complement(76..147)
                     /locus_tag="ACG8LA_002946"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(112..114),aa:Glu,seq:ttc)
     gene            complement(159..232)
                     /locus_tag="ACG8LA_002947"
     tRNA            complement(159..232)
                     /locus_tag="ACG8LA_002947"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(196..198),aa:Ile,seq:gat)
     gene            complement(245..315)
                     /locus_tag="ACG8LA_002948"
     tRNA            complement(245..315)
                     /locus_tag="ACG8LA_002948"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(281..283),aa:Gly,seq:tcc)
     gene            complement(320..392)
                     /locus_tag="ACG8LA_002949"
     tRNA            complement(320..392)
                     /locus_tag="ACG8LA_002949"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(357..359),aa:Phe,seq:gaa)
     gene            complement(396..468)
                     /locus_tag="ACG8LA_002950"
     tRNA            complement(396..468)
                     /locus_tag="ACG8LA_002950"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(433..435),aa:Asp,seq:gtc)
     gene            complement(487..560)
                     /locus_tag="ACG8LA_002951"
     tRNA            complement(487..560)
                     /locus_tag="ACG8LA_002951"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(524..526),aa:Met,seq:cat)
     gene            complement(573..662)
                     /locus_tag="ACG8LA_002952"
     tRNA            complement(573..662)
                     /locus_tag="ACG8LA_002952"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(624..626),aa:Ser,seq:tga)
     gene            complement(685..756)
                     /locus_tag="ACG8LA_002953"
     tRNA            complement(685..756)
                     /locus_tag="ACG8LA_002953"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(721..723),aa:Glu,seq:ttc)
     gene            complement(778..865)
                     /locus_tag="ACG8LA_002954"
     tRNA            complement(778..865)
                     /locus_tag="ACG8LA_002954"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(829..831),aa:Ser,seq:gct)
     gene            complement(890..963)
                     /locus_tag="ACG8LA_002955"
     tRNA            complement(890..963)
                     /locus_tag="ACG8LA_002955"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(927..929),aa:Ile,seq:gat)
     gene            complement(977..1047)
                     /locus_tag="ACG8LA_002956"
     tRNA            complement(977..1047)
                     /locus_tag="ACG8LA_002956"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1013..1015),aa:Gly,seq:tcc)
     gene            complement(1049..1124)
                     /locus_tag="ACG8LA_002957"
     tRNA            complement(1049..1124)
                     /locus_tag="ACG8LA_002957"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1089..1091),aa:Asp,seq:gtc)
     gene            complement(1143..1216)
                     /locus_tag="ACG8LA_002958"
     tRNA            complement(1143..1216)
                     /locus_tag="ACG8LA_002958"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1180..1182),aa:Met,seq:cat)
     gene            complement(1229..1318)
                     /locus_tag="ACG8LA_002959"
     tRNA            complement(1229..1318)
                     /locus_tag="ACG8LA_002959"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1280..1282),aa:Ser,seq:tga)
     gene            complement(1342..1415)
                     /locus_tag="ACG8LA_002960"
     tRNA            complement(1342..1415)
                     /locus_tag="ACG8LA_002960"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1379..1381),aa:Ile,seq:cat)
     gene            complement(1429..1502)
                     /locus_tag="ACG8LA_002961"
     tRNA            complement(1429..1502)
                     /locus_tag="ACG8LA_002961"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1466..1468),aa:Met,seq:cat)
     gene            complement(1530..1602)
                     /locus_tag="ACG8LA_002962"
     tRNA            complement(1530..1602)
                     /locus_tag="ACG8LA_002962"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1567..1569),aa:Ala,seq:tgc)
     gene            complement(1622..1695)
                     /locus_tag="ACG8LA_002963"
     tRNA            complement(1622..1695)
                     /locus_tag="ACG8LA_002963"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1659..1661),aa:Pro,seq:tgg)
     gene            complement(1705..1778)
                     /locus_tag="ACG8LA_002964"
     tRNA            complement(1705..1778)
                     /locus_tag="ACG8LA_002964"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1742..1744),aa:Arg,seq:acg)
     gene            complement(1789..1874)
                     /locus_tag="ACG8LA_002965"
     tRNA            complement(1789..1874)
                     /locus_tag="ACG8LA_002965"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1838..1840),aa:Leu,seq:taa)
     gene            complement(1891..1962)
                     /locus_tag="ACG8LA_002966"
     tRNA            complement(1891..1962)
                     /locus_tag="ACG8LA_002966"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1928..1930),aa:Gly,seq:gcc)
     gene            complement(1974..2046)
                     /locus_tag="ACG8LA_002967"
     tRNA            complement(1974..2046)
                     /locus_tag="ACG8LA_002967"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2011..2013),aa:Thr,seq:tgt)
     gene            complement(2064..2145)
                     /locus_tag="ACG8LA_002968"
     tRNA            complement(2064..2145)
                     /locus_tag="ACG8LA_002968"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2109..2111),aa:Leu,seq:tag)
     gene            complement(2153..2225)
                     /locus_tag="ACG8LA_002969"
     tRNA            complement(2153..2225)
                     /locus_tag="ACG8LA_002969"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2190..2192),aa:Lys,seq:ttt)
     gene            complement(2229..2301)
                     /locus_tag="ACG8LA_002970"
     tRNA            complement(2229..2301)
                     /locus_tag="ACG8LA_002970"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2266..2268),aa:Val,seq:tac)
BASE COUNT          630 a          636 c          542 g          504 t
ORIGIN      
        1 aaagataact ctgctaagct ttttaaaatc attctttcag ataaaaagaa aaagatactc
       61 aaaaagtatc ttccatgacc cgtacgggat tcgaacccgt gttaccgccg tgaaagggcg
      121 gtgtcttaac cgcttgacca acgggccaat aaaataaatg ggcctaaatg gactcgaacc
      181 atcgacctca cgcttatcag gcgtgcgctc taaccagctg agctataggc ccataaaaac
      241 taaaagcggg tgacgagaat cgaactcgcg acaacagctt ggaaggctgt ggttttacca
      301 ctaaactaca cccgcataat ggcgcgggac agaatcgaac tgccgacaca tggagcttca
      361 atccattgct ctaccaactg agctaccgag ccaaacggtt ccgacgggaa tcgaacccgc
      421 gatctcctgc gtgacaggca ggcatgttaa cccctacacc acggaaccaa tgtttttagt
      481 ttttaattgc gggagcagga tttgaaccta cgaccttcgg gttatgagcc cgacgagcta
      541 ccagactgct ccatcccgcg ataatatgaa aaaggaggat aagggattcg aacccttgca
      601 cggttttacc cgcctgacgg ttttcaagac cgttcccttc agccggactt gggtaatcct
      661 ccatgtaaaa ctatattaaa ttaatgaccc gtacgggatt cgaacccgtg ttaccgccgt
      721 gaaagggcgg tgtcttaacc gcttgaccaa cgggccaggt aaaacaaaat attgaaacgg
      781 agaaggaggg atttgaaccc tcgcgccggt ttcccgacct acacccttag caggggcgcc
      841 tcttcagcca cttgagtact tccccaaaac caataagatt ttgtactaat gggcctaaat
      901 ggactcgaac catcgacctc acgcttatca ggcgtgcgct ctaaccagct gagctatagg
      961 cccataaaaa actaaaagcg ggtgacgaga atcgaactcg cgacaacagc ttggaaggct
     1021 gtggttttac cactaaacta cacccgcatg gcggttccga cgggaatcga acccgcgatc
     1081 tcctgcgtga caggcaggca tgttaacccc tacaccacgg aaccagtgtt tttagttttt
     1141 aattgcggga gcaggatttg aacctacgac cttcgggtta tgagcccgac gagctaccag
     1201 actgctccat cccgcgataa tatgaaaaag gaggataagg gattcgaacc cttgcacggt
     1261 tttacccgcc tgacggtttt caagaccgtt cccttcagcc ggacttgggt aatcctccat
     1321 atgaaactta caacgccaca atggaccttg taggactcga acctacgacc ggacggttat
     1381 gagccgtctg ctctaaccaa ctgagctaaa ggtccaggct cttaaaaatc gcggcggagg
     1441 ggatcgaacc cccgacctcc cgggtatgaa ccggacgctc tagccagctg agctacaccg
     1501 cgaaaaagat attcattatt taaatgaaat ggagcctagc gggatcgaac cgctgacctc
     1561 ctgcgtgcaa agcaggcgct ctcccagctg agctaaggcc ccgtgtttaa atttataatt
     1621 atcgggaaga caggattcga acctgcgacc ccttggtccc aaaccaagtg ctctaccaag
     1681 ctgagctact tcccgtttaa ttaacgcgcc caagaggagt cgaaccccta accttttgat
     1741 ccgtagtcaa acactctatc cagttgagct atgggcgcat atttgaaatg ccgaggaccg
     1801 gaatcgaacc ggtacggtga tcactcaccg caggatttta agtcctgtgc gtctgccagt
     1861 tccgccaccc cggcgcgatt gctttggcaa agcggaaaac ggggttcgaa cccgcgaccc
     1921 ccaccttggc aaggtggtgc tctaccactg agctatttcc gcgtgtttaa agatgccggc
     1981 taaaggactt gaaccctcga ccctctgatt acaaatcaga tgctctacca actgagctaa
     2041 gccggcatgt aaaacttaaa ttatgcgggt gaagggactt gaacccccac gccgtaaggc
     2101 gctagatcct aaatctagtg cgtctgccaa ttccgccaca cccgcaaaaa tatgagccgt
     2161 acagggctcg aacctgtgac cctctgatta aaagtcagat gctctaccaa ctgagctaac
     2221 ggctcatatg gaggttaacg ggatcgaacc gctgaccctc tgcttgtaag gcagatgctc
     2281 tcccagctga gctaaacctc catggataac tt
//
LOCUS       DAZKKZ010000158         2258 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.168, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000158 DAZKKZ010000000
VERSION     DAZKKZ010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2258)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2258)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2258
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.168"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            41..163
                     /locus_tag="ACG8LA_002971"
     CDS             41..163
                     /locus_tag="ACG8LA_002971"
                     /inference="COORDINATES: protein motif:HMM:NF024811.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0205186.1"
                     /translation="MHKPFPDPIQKAIDELGIKNKKRFILVIHYMTCKVRKLVG"
     gene            136..267
                     /locus_tag="ACG8LA_002972"
     CDS             136..267
                     /locus_tag="ACG8LA_002972"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0205187.1"
                     /translation="MQSAKACGIAFGLAKWGAKNIENFQSVDIIIDSPQEILDLLEK"
     gene            806..1006
                     /locus_tag="ACG8LA_002973"
                     /pseudo
     CDS             806..1006
                     /locus_tag="ACG8LA_002973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298761.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1367..1672
                     /locus_tag="ACG8LA_002974"
     CDS             1367..1672
                     /locus_tag="ACG8LA_002974"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0205188.1"
                     /translation="MVHYRKILELYFSGISQRTISSTVGSSRHTIREVTSRADRKGVT
                     ELTADMSDTWLQEYLFPEKQTTARGYLPVDWEYVHKELMKKNMTLKLLHREYGVHGT"
     gene            complement(1718..2257)
                     /locus_tag="ACG8LA_002975"
     CDS             complement(1718..2257)
                     /locus_tag="ACG8LA_002975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFQ0205189.1"
                     /translation="MEDLNIDKLFQEKASGKDIQRPEFQKLLNYIREGDCVIVASLDR
                     LGRDYEDIKNTVTFMKQKKVALKILDAQFLDFNTGNELLDTAMFDMFLSLLSYIAQNE
                     REKIRERQRQGVLLAKKAGRYKGRPIEYSENSTDPQKRLVFKTVVDMLNQGVPVAEIA
                     KENGLSRPTIYKIKKANDL"
BASE COUNT          741 a          377 c          414 g          726 t
ORIGIN      
        1 tctatatttt gatatacaaa ttacagcttc agatactaag ttgcataaac cttttccgga
       61 ccccatacaa aaggcaattg atgaattggg cataaaaaat aagaaacgat ttatattggt
      121 gattcattat atgacatgca aagtgcgaaa gcttgtggga tagcatttgg tttagctaaa
      181 tggggagcca aaaatataga aaattttcaa agtgtagata taattattga ttctcctcaa
      241 gaaatacttg atttgttaga aaaatagaca aagagcgtga gataaggata gggtctcacg
      301 ctctttgttt ttcgccattt aaagattgaa atttttgcca tttaaaaaga aaagtgacag
      361 ataggaataa aaacttatta aatgtagtta tgatctgtta tatttcattt ctaatactag
      421 gtcttccaca agcagtgttt cctgaaatgt tttctggaga ctggggtatt gtcagctatt
      481 ctatattaac attgattgct atggttttag gtacttcatt ttataatgct tttgtaagta
      541 agcatgttga ggaatatgaa gtattaatgt acttaaaaga gaaaaaaaca agtaattaat
      601 atgagaacac cacgcatagt ttttattttg agatatccta gaatgaaaca cattaagaac
      661 gaaagcaaag caaaagacgc cagaacttct actaccttct aagttttttc atatttgttt
      721 gttatgctat acatagatct gcataattag acttgcgctg cccgttattg aagtttcagg
      781 cagcgctctt tttgggggat cgataatgga agaagaaaaa atatttgaga aacgctggca
      841 gctagcatca agtgaacaaa gagcaagata caataatttg atcacctcct accccactgt
      901 tgactagaca tataaggaaa agaaatactt actttggctg tgccagttag atatagatac
      961 ctttgaaaca tttgaagtga tcctagataa aattaaacag aattgatcag aaacaagcga
     1021 agccttctct cggttcgctt gttttgctat ttattagttg gctcagggca actctaagct
     1081 cgtttgaaag aaaaccgatg gataatcccc ttgtttgtac cactttagaa tacatggatg
     1141 tacgtattgc cattgactcc tattagttac tgaaaaaaaa tttaaacaag ttgagtattg
     1201 cagataaata gctccagtga ggtgaataac tgctccactc aaggcaatag atagctccat
     1261 ccagggcaac aaactgctcc actttcatat ttaatagatg aataaccttc tgtataatag
     1321 aaaggcatac ctttcggtat gacaacttat acaggatgtt attttattgg ttcactatcg
     1381 aaaaattttg gagctttatt tttccggtat ttctcaacga acgattagtt caactgtggg
     1441 aagctccaga catacgattc gagaagttac ttctcgagca gacaggaagg gggtgactga
     1501 actaaccgct gatatgagcg atacttggct gcaggaatat ctttttccgg aaaaacaaac
     1561 aacagcacga ggttaccttc ctgtagactg ggaatatgtt cataaagaac taatgaaaaa
     1621 gaatatgaca ttgaaactcc ttcatagaga atatggggta catggaacat agaaacgaaa
     1681 atgcacggta gaaaagcgaa tgaatgtagt ataaattcta caaatcattc gctttcttta
     1741 ttttatatat ggttggtcga gagagaccat tttctttggc aatttctgca actggaactc
     1801 cttgatttaa catgtccacc acagttttaa agactaatcg tttttgcgga tctgttgagt
     1861 tctcagaata ttcaattggt cgccccttat atcgaccagc ttttttggcc aataatactc
     1921 cttgccgctg acgttcacgg attttctcac gttcgttttg tgcaatataa cttagcaatg
     1981 ataaaaacat atcgaacata gcagtatcta ggagttcatt tccagtatta aaatctaaaa
     2041 actgtgcatc tagtattttt aatgctactt ttttctgttt cataaaggta actgtatttt
     2101 ttatgtcttc ataatctctg cctaggcgat ccagtgatgc aacaatgaca caatcacctt
     2161 ctcggatata atttagtaat ttttgaaact caggtcgctg gatatcttta ccactggctt
     2221 tttcttggaa taatttatca atgttaaggt cttccatc
//
LOCUS       DAZKKZ010000159         2056 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.169, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000159 DAZKKZ010000000
VERSION     DAZKKZ010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2056)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2056)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2056
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.169"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            493..714
                     /locus_tag="ACG8LA_002976"
     CDS             493..714
                     /locus_tag="ACG8LA_002976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0205190.1"
                     /translation="MRVIKSEKFTLAEIMTTSELAQELDYNQAYVLRLAKEHLTEGKE
                     YRSAGRRNYLFSPEALKKLEKVITTKEGE"
     gene            715..972
                     /locus_tag="ACG8LA_002977"
     CDS             715..972
                     /locus_tag="ACG8LA_002977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0205191.1"
                     /translation="MPKETTINVEQLEKLLESYSNDFIELTGGKVEETTDLFDLLLTN
                     ILELNSEEQKEHKGKLIAPSYRKVAKSAVPTGFLTKQPYIF"
     gene            complement(1108..1710)
                     /locus_tag="ACG8LA_002978"
     CDS             complement(1108..1710)
                     /locus_tag="ACG8LA_002978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HFQ0205192.1"
                     /translation="MTSRKTKDERTRNWTFVVYPESAPENWREFLDELHVPWVESPLH
                     DKDVNPDGELKKPHWHVLIMFSGKKTYDQIREITQKLRSPNPQKCANAKGMVRYFAHM
                     DNPEKFQYAKSDIIAHGGAEIASYLSVTSAERYELIREMMSFVDSKNITEIKDLIDYA
                     MSERFDDWFPLLCDNSAYIIGQYIKSNRHGGSVNSKINKG"
     gene            complement(1777..1932)
                     /locus_tag="ACG8LA_002979"
     CDS             complement(1777..1932)
                     /locus_tag="ACG8LA_002979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0032993 - protein-DNA complex [Evidence
                     IEA];
                     GO_process: GO:0006276 - plasmid maintenance [Evidence
                     IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HFQ0205193.1"
                     /translation="MISNEKKRVVVTLTKEVADNLDKIAKQMGLSKSGLITIWVNANG
                     KENEQKK"
BASE COUNT          678 a          462 c          314 g          602 t
ORIGIN      
        1 aaaaaaaaac gctgaaaccc ttgggagagt aaggctaaac agctatcgac caatgaccaa
       61 tgaccaataa ggggggtgtc gtagtccccc cctcctccgc ccaattcata aacaccaaaa
      121 ccaaaaaaca aacctcaggg ctccgccccg aaccccgacc tccttctacc gaaatatatg
      181 caggcgccac gcttactatt tcgttcagct atcggctttt gcaatctaac acgaccgttt
      241 cgctaccagt cgccttacag gctccattct cgcttctctt acgtgtttta acgattgcgc
      301 cgataactaa acgaaataga cgctaaatcg cttaaaacgc aaaatagacc ctttttagag
      361 cattgatttt ttctactagt catttcgata atataaaatt gaccacaaca cagaaaactt
      421 atattataag cttatgtcgt aagtccgacg tactcacgta atatagacgg acgttaaatg
      481 gaaggagcat aaatgagagt gataaaatca gaaaaattca ctttggccga aattatgacg
      541 accagcgaac ttgcacaaga acttgattac aaccaagctt acgttttgcg cttagcgaaa
      601 gaacatctga ctgaaggaaa agaatatcgc tctgccggta gaagaaacta tcttttcagc
      661 ccagaagccc ttaaaaaact agaaaaagtc ataaccacca aagaaggtga gtaaatgcct
      721 aaagaaacaa ctatcaacgt tgaacaacta gaaaaattgc tagaatcata ttccaatgat
      781 tttatcgaat tgaccggcgg aaaagtcgaa gaaaccaccg acctctttga cctacttctc
      841 acaaatattc tggaattaaa ctctgaagaa caaaaagagc ataagggaaa actgatagca
      901 ccttcctaca ggaaggtggc taagtcggct gtgccaactg gttttcttac aaaacaacct
      961 tatatttttt gatatcacaa aaaaatccat tttggaccta ttttcggtca taatatagta
     1021 cctacttttg gtcatagttt cgtccgtagt tttggtcata gtgactaaga ctttcacgca
     1081 caaaaaaaga gctgaaatta acagctctta tcctttattt atttttgaat ttacacttcc
     1141 accatgacga ttcgatttta tatattgccc gataatataa gctgaattat cacaaagaag
     1201 cggaaaccaa tcatcaaatc tttctgacat tgcatagtca attaaatctt tgatttcagt
     1261 gatattctta gaatcaacaa acgacatcat ctctctaatc aactcatatc gttctgcact
     1321 cgttactgac aaataactag caatttctgc accaccatga gcgataatat cacttttagc
     1381 atattgaaat ttttctggat tatccatatg agcaaaatat cgcaccatac cttttgcatt
     1441 agcacatttt tgcgggtttg gagaccgaag cttttgagtt atctcacgta tttgatcata
     1501 cgtcttttta ccgctaaaca ttatcaaaac atgccaatga ggctttttca attcaccgtc
     1561 aggattcaca tctttatcat gaagtggact ctcaacccaa ggaacatgta actcatctaa
     1621 aaactccctc caattttcag gagccgattc aggatagact acaaacgtcc aattccttgt
     1681 gcgttcatct ttagtttttc tactcgtcat gctataatta ccttaattga acaacagtct
     1741 aacagcaaaa gcagtgcgcc aacactaatg cttttgctat tttttttgct cattttcctt
     1801 tccgttagca ttaacccaaa ttgtaataag accagactta ctaagaccca tttgtttcgc
     1861 aattttatca agattatctg ccacttcctt agtaagcgtt acaacgactc tctttttttc
     1921 attactgatc ataattcgta tcctccaacg actttttctt aaaaaccata gtaacaaaaa
     1981 agtaactaag gtgcaacagt ttagatacta attagcgaat aataggcctt aaacccttgg
     2041 cattactgat tttgtc
//
LOCUS       DAZKKZ010000160         2048 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.170, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000160 DAZKKZ010000000
VERSION     DAZKKZ010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2048)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2048)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2048
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.170"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..197
                     /locus_tag="ACG8LA_002980"
     CDS             <1..197
                     /locus_tag="ACG8LA_002980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010868911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HFQ0205194.1"
                     /translation="NNLIEQDHRPIKRRNKFYRSLRTASSTIKGMETIRGIYKKNRRN
                     GTLFGFSVSTEIKVLMGIPA"
     gene            280..897
                     /locus_tag="ACG8LA_002981"
     CDS             280..897
                     /locus_tag="ACG8LA_002981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011834674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0205195.1"
                     /translation="MWIFKQEIFAKLFSLDGLGWGILFFIFLFLGSMWIWFVDKKNSY
                     EKVIVKKMNRNEFDDFSKEHRVELYDSHEINSTSPSYYWVFGCEEKPLEIKLLKMLEN
                     PPVIEDFSAKNVEKQMFEQVQIRGQNKISLEPDEYAAFFLETNSGTSMPVFKVKLKMN
                     GRLCTYDLVANMRYGSTGDRRTILKFEQTFRSFLKNRVSQIFNLD"
     gene            1061..1393
                     /locus_tag="ACG8LA_002982"
     CDS             1061..1393
                     /locus_tag="ACG8LA_002982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0205196.1"
                     /translation="MNNREILAKEMADLKAKEAKIRAKRKQIRQKEMISLAKLYCKKE
                     GFKTPAEALDFLESNKRNHSVNDEVLVSLRKFADGLVWQENGAYWRTNDVKGLTQFMA
                     QFRSENVN"
     gene            1717..1878
                     /locus_tag="ACG8LA_002983"
     CDS             1717..1878
                     /locus_tag="ACG8LA_002983"
                     /inference="COORDINATES: protein motif:HMM:NF013258.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid recombination protein"
                     /protein_id="HFQ0205197.1"
                     /translation="MAYMVARTQKHKVGSLNGLQNHVDRKTKNHTNKDIDITKSGSVA
                     KFSKKSILV"
     gene            1910..2048
                     /locus_tag="ACG8LA_002984"
                     /pseudo
     CDS             1910..2048
                     /locus_tag="ACG8LA_002984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477736.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
BASE COUNT          731 a          261 c          411 g          645 t
ORIGIN      
        1 tgaacaattt aatagaacaa gaccatcgac ctattaagcg acggaataaa ttttatcgaa
       61 gtctccggac tgcctcatcc acgattaagg ggatggagac cattcgagga atatataaaa
      121 agaaccgaag aaatggaacg ctcttcggct tttcggtgtc tactgagatc aaggtattaa
      181 tgggaatacc agcctaagat atttggagtt cagagagggc gcgtttgatt ttcaaacttc
      241 gcaacagaac cattatttta aagtgggagg aaaattgttt tgtggatatt taaacaagaa
      301 atctttgcta aattatttag tttagatgga ttaggttggg gaatcttatt ttttattttt
      361 ttatttttag gatctatgtg gatctggttt gttgataaaa aaaattctta tgagaaagta
      421 atagtgaaaa aaatgaatcg aaatgaattc gatgattttt caaaggaaca tagagttgaa
      481 ttgtacgata gtcatgaaat taacagtact tctccatctt attattgggt atttggttgc
      541 gaagaaaaac cattggagat taaattgttg aaaatgcttg aaaatcctcc agtcattgaa
      601 gatttttctg caaaaaacgt tgaaaaacag atgtttgaac aggtacaaat aagaggtcaa
      661 aacaaaattt cattagaacc agatgaatat gcagcctttt ttttagaaac aaattcaggt
      721 acttcaatgc ctgttttcaa agttaaatta aaaatgaatg gtcgtttatg cacttatgat
      781 cttgttgcaa atatgcgcta tggttctact ggtgatagac gtactatttt aaaatttgag
      841 caaaccttta gaagtttttt gaaaaataga gtatcccaaa tttttaattt ggattgaaaa
      901 aattaaaaat ttggccaaaa atactacagt tttttagagc aatcatctta tgatgattgc
      961 tctttttttg ttgtttttgt gtcattcgtt gttcaaatcc tctattcgta aaataaatat
     1021 tttaaactag aaatatgcct tatttttagg aggaatcaaa atgaacaata gagaaatatt
     1081 ggcaaaagaa atggcggatt tgaaagcaaa agaagcgaag attagagcga aacgaaaaca
     1141 gattagacag aaagaaatga tttctttagc gaaattatat tgtaaaaagg aaggctttaa
     1201 gacacctgct gaagcattag attttttgga atcaaataaa agaaatcatt cagtaaatga
     1261 tgaggtttta gtatcgctaa gaaaatttgc agatggatta gtttggcaag aaaatggtgc
     1321 atattggcgt acgaatgatg ttaagggttt gactcaattt atggcacaat ttcgttcaga
     1381 aaatgtgaac taaattgagg aggggttgaa gtgaaaagca atacttttca cttttggttt
     1441 tttgcggaat aaaaattgtg aaaacaatga cgcaaaaagc caatggtttt gaacgaaaaa
     1501 aggacgtaaa aaaggaatgc gaaggcagtc gtttttcgtt cgctttttcg tttgagagaa
     1561 acggagtttc tcatcggctg ttaagccgat atagccctcg gcagagctta cagactttac
     1621 gcagtataag tctagtaagt tataccttac atggaggttt ttccgaattt agcttgtgat
     1681 tctcgcaata attttaacga aaggaagtac acagttatgg cctatatggt ggcacgaaca
     1741 caaaagcata aagttgggtc gttaaatgga cttcaaaatc atgtagatcg taaaacgaaa
     1801 aatcatacga ataaagacat tgatattacg aaaagtggtt ctgttgcaaa gttttccaaa
     1861 aaatctattt tagtgtaaaa ttgagaaaaa agacagagag gatagagtaa tgaatcattt
     1921 taaaggcaaa caattcaaaa aatgacgtca ttattgtcgc tgttagttac tacctgcgtt
     1981 acaatctaag ctatcgtgaa gttcaggaat tgttatatga tcgtggaata aatgtttgtc
     2041 atactacg
//
LOCUS       DAZKKZ010000161         2008 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.171, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000161 DAZKKZ010000000
VERSION     DAZKKZ010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2008)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2008)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2008
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.171"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            64..972
                     /locus_tag="ACG8LA_002985"
     CDS             64..972
                     /locus_tag="ACG8LA_002985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate upper protein"
                     /protein_id="HFQ0205198.1"
                     /translation="MAKWNVILSTTEPYNYVGMIQVRQGNKNTEVMEATIVENGLPYD
                     LSECKVYFESVVGGKYPVQLETKIVDAKKGKIKYIFDKYSMQCLHRQTANFIIFKGED
                     LIGTTQDFSYFVINAVSKTEGEMGSYWQSIEDLIADMTDFINENKGDFTDWMNERKEE
                     FDRWREEQENSFQDWREGQESDYLSWFESIKDILKSIDPGGVMLAELMDARVDLQGVR
                     HESISERFLSDLNYLYQKMKAALFTIEYGEIEVTDILQDDLFSDNHEVEKIETVEFPI
                     EEGALIIATVDDPKQNVFTLEKVGVI"
     gene            972..1589
                     /locus_tag="ACG8LA_002986"
     CDS             972..1589
                     /locus_tag="ACG8LA_002986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0205199.1"
                     /translation="MVKVKRMMETDESGVKRQFMPITHVSAVLGLEKMISGQSKVLSV
                     NGKYGAVILTKADLGLENAITELPYASETSDGILTAEMFQKIVNGEGGTYILPIATPE
                     QLGGIKVGELLEVTEEGVLSATKQTDFNFSEELKGKLESLKILKAGANISIAEDGTIS
                     STGGSGTGGVNQSYVDQKFQEAVNQAENYTNERIPNFTFEKIGEV"
     gene            1593..>2008
                     /locus_tag="ACG8LA_002987"
     CDS             1593..>2008
                     /locus_tag="ACG8LA_002987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0205200.1"
                     /translation="MTDIVKIKQSNVQVYPQTHWNAIEGKPTMVKGDKGDPGQAATIT
                     IGTVSSGSTASVTNVGTSSAARFNFVLPKGDKGDPGINATTTAVATTTANGLMSSTDK
                     TKLDGIAAGAQKNPGNATTTTAGLMSATDKVKLDGLA"
BASE COUNT          732 a          288 c          426 g          562 t
ORIGIN      
        1 cagtattata gtgcaagtgc aatttcttcc attgtcatac caccaaaata gggaggtgat
       61 ttaatggcaa agtggaatgt catattaagt acaacagaac cctataatta cgtggggatg
      121 attcaagttc gacaaggcaa taaaaacact gaagttatgg aagctacaat tgtcgaaaat
      181 ggtcttccat atgatttatc agaatgtaag gtatattttg aatcagttgt tggcggaaaa
      241 tatccagtcc aattagaaac aaaaattgtg gatgctaaaa aagggaaaat caaatatatt
      301 tttgataaat attccatgca gtgtttgcat cgacaaacag ccaatttcat tatatttaaa
      361 ggagaagact tgattggaac aactcaagac ttctcttatt ttgtcatcaa tgctgtttca
      421 aaaacagaag gagaaatggg ttcttattgg caatcaattg aagatttaat tgctgatatg
      481 acagatttta ttaatgaaaa taaaggcgat tttacggact ggatgaatga aaggaaagaa
      541 gaatttgatc gctggagaga ggaacaggag aatagtttcc aagattggag agaaggacaa
      601 gaatcagatt acttgtcatg gtttgaatca atcaaggata ttttgaagtc tatcgatcca
      661 ggtggagtaa tgttagccga attaatggat gcacgtgtag atcttcaagg tgtacgccat
      721 gaatcgattt ctgaacgttt cctatccgat ctaaattatt tgtatcaaaa aatgaaagca
      781 gcacttttca cgattgaata cggtgaaatt gaagtgactg atattcttca agacgatctc
      841 ttttcagata atcacgaagt cgaaaaaatt gaaacagtag aatttccaat tgaagaagga
      901 gctttgatta ttgcaactgt tgatgatcca aaacagaatg ttttcactct tgagaaagtt
      961 ggggtgattt gatggttaaa gtaaagagaa tgatggaaac tgatgaatct ggtgttaaac
     1021 gtcaatttat gccaattaca catgtctctg cagttttagg cttagaaaaa atgatatcag
     1081 gacaatcaaa agttctttcg gttaatggta aatatggtgc agtcatttta acgaaagctg
     1141 atttaggatt agagaatgca attactgaac taccttatgc aagcgagaca agcgatggta
     1201 ttcttactgc tgaaatgttt caaaagatcg taaatggaga aggtggaaca tatattttgc
     1261 cgattgctac tcctgaacaa ttaggaggta taaaagttgg ggaactctta gaagttactg
     1321 aagaaggtgt tttatctgca actaagcaaa cagacttcaa tttctctgaa gaattaaaag
     1381 gaaaattaga atctctaaaa atattaaaag caggtgcaaa tatatcaatt gcagaagatg
     1441 gaacaattag ttctacaggt ggtagtggga ctggtggtgt taatcagtca tatgtagatc
     1501 aaaaattcca agaagctgta aatcaagcag aaaattacac aaacgaaaga attccaaatt
     1561 ttacttttga aaaaattggg gaggtataga gaatgacaga tatcgtaaaa ataaaacaaa
     1621 gcaatgtaca ggtttatcca caaactcatt ggaatgctat agaaggcaaa ccaacaatgg
     1681 tgaagggaga taaaggcgat cctggccaag cagcaacaat taccatagga accgtttcta
     1741 gtggttcaac cgcttctgtt acgaatgtag gaacatcatc tgcagctaga tttaattttg
     1801 ttttaccaaa gggagataaa ggtgatcctg gaataaatgc cacaactaca gctgtagcta
     1861 caactacagc aaatgggttg atgtcgtcca cagataaaac taagttggat ggaattgcag
     1921 ctggagcaca gaaaaatcca ggtaatgcta caactacgac agcaggttta atgtcagcaa
     1981 ccgataaagt gaaacttgat ggattagc
//
LOCUS       DAZKKZ010000162         2004 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.172, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000162 DAZKKZ010000000
VERSION     DAZKKZ010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2004)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2004)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2004
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.172"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(58..408)
                     /locus_tag="ACG8LA_002988"
     CDS             complement(58..408)
                     /locus_tag="ACG8LA_002988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0205201.1"
                     /translation="MIDYNDRGRLKWTGFYLSDHTEEIDADNEQRANQNLAKEQITTE
                     EISEVLNAAVIKNRLVCIQKEERNAEGYYPYDIVGKILGSDELGIYVGKDKIHYDEIR
                     HIEFYQDNKWSRLE"
     gene            complement(401..1726)
                     /locus_tag="ACG8LA_002989"
                     /pseudo
     CDS             complement(401..1726)
                     /locus_tag="ACG8LA_002989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
BASE COUNT          565 a          413 c          315 g          711 t
ORIGIN      
        1 aatatttgta tataactata catgttatat actttagctc atattgctgg ataatgttca
       61 ttctagtcga ctccacttat tatcctggta aaattcaatg tgccgtattt cgtcgtagtg
      121 aattttgtct tttccaacgt agattcccag ctcatcacta cctaagatct ttccaacaat
      181 atcgtatgga tagtatcctt cagcatttcg ttcttctttt tgaatacata ctaatctatt
      241 ttttatgact gcagcgttca atacttccga aatctcttca gtcgttattt gttcttttgc
      301 taagttttga ttggctcgct gttcattatc tgcatcgatc tcttccgtgt gatcggataa
      361 atagaatcct gtccatttca atcgtcctcg atcgttatag tcaatcattt ttaagccccc
      421 ctgcaccgcc tgcatggcca ccaaccaacg tgcttctagt aatactacga gcgccttcta
      481 acatcgaaga agcatgtaca attgacgtaa aaccatactt ctgcctaatt ttatctatta
      541 ttttgtctag tttttcgtca tcaatctgtt tttgtggatc actaaacaag tccagctgaa
      601 gcgaatcggt gtacacaagc ttgctatagg ttattccaac gtgccttact tcttgtcctt
      661 cataatactt atcaaacaag aaaagacaat aattctgcaa ttcctttgta ttatctgtga
      721 cagggatctt catctggtgg aaaaatcctg gtctggtctc taagatcgac gtaccaatgt
      781 ttaaatggat acatcctgtt ttacaattat gctgtctgat acgaatggct acttgttccg
      841 ccatttcttt tatcaccagc tcgatttcat ttcttctagt ataatctcgt ggtaacactt
      901 gtgaatttcc atatgatttt tcctttgtcg gttctggtgg gactgctatg tctgttcgat
      961 cgattccatt tgcatggaag tacagctgta agccaatcac acctaaacga ctcttaatag
     1021 tgtgtggatt ccaattagct aagtctttaa tactcatgat acccatttag ttgagccttt
     1081 ttttcattcg agagccaatg ccccaaagat ccgtcatttc aggaatattc catacttttt
     1141 cgggaacgtt ttcgtacgtc cattctgcaa caaatccttc attatgcttg gcttcattgt
     1201 ctaaggctag tttagccaaa aggggattat ctccgatacc taccgtagca atcaatccta
     1261 gctcttcttt aatattctcc tggatcattt gagccagctt ctttctccgt tgacttcgtg
     1321 ttccttcagt cgtaaaaagg ttcagtgatc tggtcacttt taagatcgat tcatcgatcg
     1381 agtaaatcaa taaatcttcg tctgctacat atcttctgaa gatattgttt acctgcatgt
     1441 ttcgcttaat atagagattc attcgtggtg gaacgacatg taacgtttta ggaaatggtt
     1501 gtggtaagtc acgtggtcta ctgacattag aaataccata cttcttcttt gcagctggtg
     1561 aagaagctaa aatcaaccct gatcctgtat tatctgctag actcatgacg actaattcag
     1621 tcgttaatgg atctaaaccc ctttctatac attcgacact tgcgtaaaag cttttcatat
     1681 cgatcaaaaa ggaagtattt actggctctt ttgaataatc tatcataaat aacactccat
     1741 tcgtcacaat tatacaaaca tatgttccct tttgtaaaga aggaagttca aatgaacaaa
     1801 aaaagattcg aattgttatt acaaaaagtt taaacggata actgaccact tattagattt
     1861 taaatgcgtt agaatcttca tatatcaact aattagaata aaaaaagcaa agtaactaat
     1921 gaaaatccat tagttacttt gctttttatt aaaaattttc aatcgttaaa ttactaaagt
     1981 tttttagacc actagcaaga caga
//
LOCUS       DAZKKZ010000163         1979 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.173, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000163 DAZKKZ010000000
VERSION     DAZKKZ010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1979)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1979)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1979
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.173"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(346..528)
                     /locus_tag="ACG8LA_002990"
                     /pseudo
     CDS             complement(346..528)
                     /locus_tag="ACG8LA_002990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313295.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(728..1744)
                     /locus_tag="ACG8LA_002991"
     CDS             complement(728..1744)
                     /locus_tag="ACG8LA_002991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HFQ0205202.1"
                     /translation="MANENQLSEIQSKIEGRGAEKRTTINQLEKLNRISNRRLSVQGT
                     TTPLKLNWSIDRITIVGKLNDTIAYWTKNGVVFVDFEQLMRLNENQGYLKSVGINGWQ
                     LFDQYGEDIAYIEILKFHEGKGRIDFNPNKIGQFLASSMKGFIHDLFLDPHFSRADIA
                     CDIVDVPDDFITQYRIVDPISFKPIYGRSGKLETAYWGSRASERQVRLYNKKLEQERK
                     KVIVPKEIDTWWRLEMQLRRGKATDWHAMVQESLDSFASPHFLPIDIKPIDKIVIDGL
                     IAEPSNWSIIARHTKYKYRNLLKQESQNDELTNHLRETFKESADELKKELDTWLLGLD
                     VTEK"
BASE COUNT          559 a          459 c          308 g          653 t
ORIGIN      
        1 aaaaaaataa aaagacctca gggaatttca ttccccgaac cccttgagcc tcctcctgcc
       61 gaaatggaaa gggcgcaccc gctgtttatt tcattcagct atcggttttc acaatctaac
      121 acgatcgttc cgctaccagt cgccttacag gctccatttt cgctcctcta acgtgtttta
      181 acgattgtgc cgataactaa acgaaataaa cgctaaaacc gctcagaacg caaaatatgc
      241 cattttagag ctattgtaga aaatgtagtt tgaaatgcaa ttttcttctt tcagcttttt
      301 atttcccact tgtaaatctg ctaattattt tctaccagac aaaccattga ttttttggct
      361 atcagttaac tcacgattat tatgagaaat gcttgtattc tttgttccct ttttgaacga
      421 aatactaaac cctaaggtga acccctcctt cacgctgtcg ctaataaaaa gagtgtaaac
      481 ctttctgtta ctctttgaca aagagtaaca ttttcctaat tgtgacatgg ctgtcacaat
      541 tccaaatgct ctccgagggt attcgctgtc acaagtgaca acgaaaaaag gagccgaaag
      601 cgtgtcacgc tctcaactcc ttttacgctt tattttgctt cacgcaaaat aatcgcttat
      661 cgtaaatcca cgtcactaaa cattgacgta aatttactct cactcatctg acttttctta
      721 ttcggtatca cttctctgtc acatccaacc ccaaaagcca cgtatccaat tcttttttta
      781 attcgtctgc agattcctta aaagtctctc gtaaatgatt cgttaactca tcattttgac
      841 tttcttgctt cagcaaattc cgatatttat attttgtatg tctagcaatt atcgaccaat
      901 tagaaggctc agctatcaaa ccatcaataa ctattttatc aataggtttt atatcaatcg
      961 gcaaaaaatg cgggcttgca aaactatcta agctttcctg aaccatcgca tgccaatccg
     1021 ttgctttgcc acgtcttagc tgcatttcta accgccacca cgtatcgatt tcttttggca
     1081 cgattacttt ttttcgttcc tgctctagct ttttgttgta cagtcgcact tggcgctcac
     1141 tggcacgact gccccagtac gctgtttcta gcttgccaga acggccgtag attggcttaa
     1201 aagaaatcgg gtctacaata cgatactgag taataaagtc atccggcaca tctacaatat
     1261 cgcaggcaat atccgcccgg gaaaaatgcg gatctaaaaa taggtcatga atgaatcctt
     1321 tcatggaact agctaaaaac tggcctatct tattcggatt aaaatcaata cgaccttttc
     1381 cttcatgaaa tttaagtatt tcgatatacg caatatcttc tccatattga tcgaataatt
     1441 gccagccgtt tatcccaact gatttcaaat atccctgatt ttcgttcaaa cgcattaatt
     1501 gctcgaaatc gacaaaaaca actccatttt tcgtccaata agctatggta tcattcagtt
     1561 ttccgacaat tgtaattcga tcaatcgacc aatttaattt taggggggtg gtcgtacctt
     1621 gcacacttaa ccgcctgtta gaaatacggt taagtttttc gagctgattt atcgttgttc
     1681 ttttttctgc ccctcgacct tcaatttttg attgaatttc actcaactga ttttcatttg
     1741 ccattttcgt cctccaaacg aaaaaagaga cttttggaaa gaatttccag agttcacgta
     1801 accctaaaaa ttcatatcca aaaatctcta gcttgaagaa acctaaaaat attcgtataa
     1861 tgaacctgag ttacggagct aggtgaagta gtttccgtaa atagtcgaga gtgttagcgc
     1921 actgctcggc ttttattttg ctcttttttc tcgttttctt tgattatagc actcctcct
//
LOCUS       DAZKKZ010000164         1927 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.174, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000164 DAZKKZ010000000
VERSION     DAZKKZ010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1927)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1927)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1927
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.174"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(34..735)
                     /locus_tag="ACG8LA_002992"
     CDS             complement(34..735)
                     /locus_tag="ACG8LA_002992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HFQ0205203.1"
                     /translation="MSVILISGTIGAGKSSLTDMLAKEIDSKPFYENVEDNEVLPLFY
                     SNPEQYAFLLQIFFLNKRFLAMKNALVNDDNVLDRSIYEDSLLFHLNADLGRVTDIEV
                     QQYDSLLDTMLNELDDVAPKKRPDLMVHIKVSLDTMLERIKKRGRDYEQLESDETLYT
                     YYETLNTRYNQWYEDFDVCPKIQVDGDKFDFVENPEDAKKVIRQIQEKLAELEGKPAG
                     KYFTDNQHAKGQELG"
     gene            complement(751..1191)
                     /locus_tag="ACG8LA_002993"
     CDS             complement(751..1191)
                     /locus_tag="ACG8LA_002993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside 2-deoxyribosyltransferase"
                     /protein_id="HFQ0205204.1"
                     /translation="MSQIYLAGPFFSEEQIDRVSRIEKALEENKTVTSFYSPRHHQES
                     NYELFSAGWAQEVYEKDMEELTNAEFVVAILDFEHQTIDPGTAYELGVATMLKKPMII
                     VQEETVPTNLMITQSLHTYLKSDQAVREYDFETLPVETYVGEYL"
     gene            complement(1191..1766)
                     /locus_tag="ACG8LA_002994"
     CDS             complement(1191..1766)
                     /locus_tag="ACG8LA_002994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0009691 - cytokinin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00730 family Rossman fold protein"
                     /protein_id="HFQ0205205.1"
                     /translation="MKLTVFCGSRFGNKESYKFIAQTLGKYMAQEEIELVYGGSYSGI
                     MGVISKTVLENNGKVTGIYPNGLFETELPGKDVTTFIPTETIDERKVLLFEKGDAVLV
                     FPGGLGTLEEFSQLLSWIAIGLTPDKPIGILNIGGYYSGLQQLLETFAKEDFMDKKWL
                     DQVIFSNNPLELVNELRAVSIKNQLLLKEAK"
BASE COUNT          551 a          409 c          296 g          671 t
ORIGIN      
        1 aatttttctt tcccgtcgtt tggtttttta tttttagcct aattcttgac cttttgcatg
       61 ctggttatcc gtaaaatatt ttccagcagg ctttccttcc aattcagcta atttttcttg
      121 gatctgacgg atcacctttt ttgcatcttc tggattttct acaaaatcga atttatcccc
      181 atccacttgt attttaggac atacatcaaa atcttcatac cattgattat agcgggtgtt
      241 caacgtttca taataggtat ataacgtctc atcgctttct agctgttcat agtcacgccc
      301 acgttttttg atacgttcta gcatcgtgtc caaagaaact ttgatatgga ccatcaaatc
      361 aggccgtttt tttggagcaa catcatctaa ctcgtttagc atcgtatcta ataagctatc
      421 gtactgctgt acttcgatat ccgttacccg acctaaatca gcgtttagat ggaacaacag
      481 gctatcttca tagatggatc ggtctagcac attgtcatcg ttcactaaag catttttcat
      541 tgctaaaaat cgcttgttca aaaagaagat ttgcaataaa aaagcgtact gctcaggatt
      601 tgaataaaag agcggcaata cttcgttatc ttcgacattt tcataaaatg gtttagaatc
      661 aatctctttt gcaagcatat ccgtcaaact gctcttacct gcaccaatcg ttcctgaaat
      721 caaaatcact gacatacaac ccttcctctt ctataagtac tcgcctacgt aagtttcaac
      781 aggcaatgtt tcaaaatcat attcacgtac agcttggtct gattttaaat acgtatggag
      841 actttgtgta atcatcaagt tcgtaggtac cgtctcttct tgtacaatga tcatcggttt
      901 tttcaacata gttgccacac ctaattcgta agccgttcct ggatcgattg tttgatgctc
      961 aaagtcaagg atagcaacaa caaattctgc atttgtcagt tcttccatat ctttttcgta
     1021 tacttcctgc gcccatccag cgctgaatag ttcataattg ctttcttggt gatgacgtgg
     1081 agagtagaaa cttgtgactg ttttgttttc ctccaacgct ttttcgatac gacttactcg
     1141 atcgatttgc tcctctgaaa aaaatggtcc tgctaaatat atttgactca ttattttgcc
     1201 tccttcaata ataactgatt tttaatagat actgctcgta attcattgac cagttccaat
     1261 ggattgttgg aaaagattac ttgatccaac cattttttat ccataaaatc ctcttttgca
     1321 aaagtttcta ataattgttg caagccgctg taataaccgc caatattcaa tattccgatt
     1381 ggcttgtcgg gcgtcagacc gattgctatc caagaaagaa gttgtgagaa ttcctccaat
     1441 gtacctagac ctccagggaa aacgaggaca gcatctccct tttcaaataa taataccttt
     1501 ctttcatcga tcgtttctgt aggaataaat gtagtaacat cttttccagg caattcagtt
     1561 tcaaaaagcc cattcggata gatacctgtg acttttccgt tattttccag tactgtttta
     1621 ctaatcactc ccataatccc ggagtatgaa ccaccgtaaa ccagttcgat ttcttcttgt
     1681 gccatgtatt ttcctaacgt ttgcgcaata aatttgtaac tttctttatt accaaaacgg
     1741 gaaccgcaaa aaacagtaag tttcataaaa aaacactccc taactcaaaa gtctatcttc
     1801 attctacacg tgttttttta aaataaaaga ctagattttg tagtttttta gtggtatata
     1861 ggatagacgc cactatatat agtatttaga aaaaaatcat ttttcagcca ttttatagat
     1921 aaaacaa
//
LOCUS       DAZKKZ010000165         1925 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.175, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000165 DAZKKZ010000000
VERSION     DAZKKZ010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1925)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1925)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1925
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.175"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            91..387
                     /locus_tag="ACG8LA_002995"
     CDS             91..387
                     /locus_tag="ACG8LA_002995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgN"
                     /protein_id="HFQ0205206.1"
                     /translation="MSLKNYVYSHPVNVFIIGRLGLSVEVFCELYGFKQGTLSSWVTR
                     EKTVASLPIEFLHGLSLASGETMDQVYDCLCVLEQEYIEYKIANELRKRKKYIQ"
     gene            488..1339
                     /locus_tag="ACG8LA_002996"
     CDS             488..1339
                     /locus_tag="ACG8LA_002996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0205207.1"
                     /translation="MKSDDWIEHTWLPLKRNSKRKKFWVLQLWPLGKLCSYGARLILD
                     LTVYSIGVFGTAYYLINDPNRIAASDIFTVLMTLIFVMLLSIFTQLVMQFTRQKLTAG
                     KLFKSLFDLIVVNAILATLIKQIEQSGRTTKGVKDFLLTFIHFVNGHMYLFEVGIILF
                     FVGYVSTKLIKRSIEKEIEIDLIPTLLGYEYNVDFGRYDELINTDIVHTSIHESTVKG
                     IRSILKNGQEMKAIDRRKEIYNFYEVEASLRYGIGKLWLDGSNIRQNKPYIFWNSSDL
                     ELPMKDK"
     gene            1360..1572
                     /locus_tag="ACG8LA_002997"
     CDS             1360..1572
                     /locus_tag="ACG8LA_002997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0205208.1"
                     /translation="MIPLYRIVLIVGMELKTLKKEQLFKVKERHNQLLCSKTGTMNIE
                     YRTEYLELTNQTDFLLIRKQQEQEKN"
BASE COUNT          664 a          250 c          411 g          600 t
ORIGIN      
        1 ttctgtaggt gttgctccct ttgcctagct acgtgtaggt ggtatactta taactgcgta
       61 tgcagtctta tgtatcatgg aggaagttgt atgtcgttaa aaaattatgt ctattcacat
      121 cctgttaatg tgtttatcat tggtcgtttg ggattatctg tggaagtgtt ctgtgagctt
      181 tatggtttta agcaggggac tttgtcttct tgggttacca gggaaaaaac agttgcttct
      241 ttgccgattg agtttcttca tgggttgtcc ttagcttctg gggagactat ggatcaggta
      301 tatgattgtt tgtgtgtgtt agagcaggag tatattgagt ataaaatagc taacgagtta
      361 agaaaaagga agaagtatat ccagtagtag tttttattta cttaaaaaat tggttcattg
      421 agcaacctat cgctgctaaa gtagcaaagg aaaacgttaa aggaaagaat ttagggaaga
      481 aatcgaaatg aaatcggacg actggattga acacacctgg cttcctctga aaagaaatag
      541 caaacgaaag aaattttggg tattgcaatt atggccatta ggaaaacttt gtagttacgg
      601 ggcacgactt attcttgatt taaccgttta ctcgattgga gtatttggaa cggcttatta
      661 cttgataaat gatcccaata ggattgcagc atcagacatt tttacagtgc taatgacgtt
      721 gatttttgtc atgctattgt ctatttttac tcaattagtc atgcaattta ccaggcaaaa
      781 attaacagca ggaaaacttt tcaaaagcct attcgattta attgttgtaa atgcaattct
      841 agcgacttta ataaaacaaa ttgaacaatc tggaagaaca acaaaaggag tgaaggattt
      901 tttattgacg tttattcact ttgtaaatgg acacatgtat ttgtttgaag tgggtattat
      961 tctctttttt gtcgggtatg tatccacgaa acttattaaa cgttcaattg aaaaagaaat
     1021 tgaaattgac ctgattccga cacttcttgg ttatgagtac aatgttgatt ttggaagata
     1081 tgacgaattg atcaatacgg atatcgttca cacgagtatc catgaatcta ctgttaaggg
     1141 catcagatct attttaaaaa atggccagga aatgaaagca atagatcgaa gaaaagagat
     1201 ctacaatttt tatgaagtcg aagcaagcct acgatatggc atcggaaaat tgtggttaga
     1261 tggaagtaat attcgtcaaa acaaaccata cattttttgg aacagtagtg atttagaact
     1321 tccaatgaaa gataaataat tatggagaat cgtttgaaaa tgattcctct atacaggatt
     1381 gtgcttatag ttggcatgga gttaaaaacc ttaaagaagg agcagttatt caaagtgaaa
     1441 gaacgtcata atcagttact atgtagtaaa acgggtacga tgaacattga ataccgaaca
     1501 gaatatttag aattaacgaa tcaaactgat tttttgttga ttcgaaagca acaagagcaa
     1561 gaaaaaaatt aatggctact tatagccaat tgattgatga atgggaacaa ttcaaggaat
     1621 ctaaaattcc agaacgtctc taaaagcctt tatttgtaaa gagcataagg aaacgtggga
     1681 acacttttta aaaaaagtgt tccaataggc tgtgcctatt acgtttctca aaaataaatg
     1741 tgggaacaaa atatttaaaa ataggatagt gaaaggatag tgaaggatag taaaaggagg
     1801 gtagtaggat agcaaaaagg ataggctcct tttcgctatc ctttttaaat tggaggaatt
     1861 aatatggaag taagaataag aaatgtggat gagaaaatcg taagagaaat tgatcgaaga
     1921 tgtga
//
LOCUS       DAZKKZ010000166         1924 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.176, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000166 DAZKKZ010000000
VERSION     DAZKKZ010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1924)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1924)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1924
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.176"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            156..1862
                     /gene="efbA"
                     /locus_tag="ACG8LA_002998"
     CDS             156..1862
                     /gene="efbA"
                     /locus_tag="ACG8LA_002998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding protein EfbA"
                     /protein_id="HFQ0205209.1"
                     /translation="MSFDGVFTHAMVNELRETLLSGRISKIHQPYENEIVLVIRSRGK
                     NHRLLLSAHPSYARVQITQIDYQNPDNPPNFVMMLRKYLDGAILEDIEQIENDRVIHF
                     HFAKRNELGDLQNIILIVELMGRHSTIVLVNRETGKILDAIKHIGSSQNTYRSLLPGV
                     EYVAPPKQEVLNPFSSEKEKIFQRLSQTELDPKAIQRQFQGIGFDIAQELTKRLLERP
                     NEKMVVWDEFFSAISHQPIPTFYETENKDFFTPIAYQVLSEQASAVTAYPTLSQLLDS
                     YYHEKAEKDRAKQQGGELIRKIENELKRNKNKLKKREQTLKESENAENYRRNGELLTT
                     FLTQVPRGAKEVVLPNYYEEDRPIKIALDPALTPNQNAQKYFHRYQKLKNAVKLIGEQ
                     IQEAKDEIQYLESVLSQLEIAGPMDIEAIKEELTSEGYLKKKNLKKQKRKKPSQPDQY
                     FSSDGTLILVGKNNLQNDQLTMKTAKKTDYWLHAKNIPGSHVIIKSDKPSDETITEAA
                     ELAAYFSKYRYSAQVPVDLVQVKHIRKPNGAKPGYVIYENQKTIIVTPEEEKITAMKQ
                     NR"
BASE COUNT          687 a          384 c          345 g          508 t
ORIGIN      
        1 acctaaaaat ttggatttca acgatagaaa cactgttttt tatgtaatta gtccaagatt
       61 tttctagact tttgctttac tattcggcca aattggtttt tcttcttttt ttcgttataa
      121 tgaatatact tatgaaaaga aatgaggaat gaaccatgtc ctttgatggt gtatttaccc
      181 acgcgatggt caacgaattg cgtgaaacgt tactatctgg ccggatctcg aaaatccatc
      241 agccttatga aaatgaaatc gtgctggtga ttcgttcacg cggcaaaaac catcgattat
      301 tattatctgc gcacccaagt tatgctcgtg tacagattac ccaaatcgat tatcagaatc
      361 ctgataatcc gcctaacttc gtgatgatgc ttcgaaaata tttggatggc gctattttag
      421 aagacatcga acaaatcgaa aatgatcgag tgatccattt ccactttgct aaacgaaacg
      481 agttgggtga tctacaaaat atcatattga tcgttgaatt aatgggacgt catagtacga
      541 tcgtcttagt taatcgagaa actggaaaaa tactggatgc gatcaaacac attggaagct
      601 ctcaaaacac ttatcgttct ttgcttcctg gtgtagaata tgttgctccg ccaaaacaag
      661 aggtcttgaa cccatttagc tccgagaaag aaaaaatctt tcagcggctt tcccaaactg
      721 aactagatcc aaaagcaatc caacgtcagt ttcagggaat cggtttcgat atcgctcaag
      781 agctgaccaa aagattactg gaacgtccta atgaaaagat ggttgtatgg gacgaatttt
      841 tctcagccat cagccatcag cctattccta ctttttacga aacggaaaat aaagattttt
      901 tcacaccgat tgcttatcag gtattgtccg aacaggcatc tgctgtaaca gcttatccaa
      961 cactcagtca attattagat agctattatc acgaaaaagc agagaaagat cgggcaaaac
     1021 aacaaggcgg agaactgatt cgaaaaatcg aaaatgaact aaaacgaaat aaaaataaat
     1081 tgaaaaaacg tgaacaaaca ctcaaagaat ccgaaaacgc tgagaattac cgtagaaatg
     1141 gcgaactact tactactttt ctgacacaag taccacgcgg cgcaaaagaa gttgttttac
     1201 ctaattatta tgaagaagat cggccaatca aaatagcact agatccggca ttgacaccaa
     1261 atcaaaatgc acagaaatat ttccatcgat accaaaagct gaagaacgct gttaagctga
     1321 ttggcgaaca aatccaagaa gccaaagatg aaatccaata tcttgaatct gtcttatctc
     1381 aactggaaat tgccggccca atggatatcg aagcaattaa agaagaattg acttcagaag
     1441 gatacctgaa aaagaagaac ttaaaaaaac aaaaacgtaa gaaaccatct cagcctgatc
     1501 aatacttttc ttctgacgga acgctcattc ttgttggtaa aaacaatctt caaaatgacc
     1561 agctgacaat gaagacagct aaaaaaaccg actattggct tcatgcaaaa aatatacccg
     1621 gttcgcacgt catcattaaa agtgacaagc cctcagatga aacaattaca gaagctgccg
     1681 agttagctgc ctatttttca aaataccgat actctgccca agtgccggtt gatcttgtac
     1741 aggtaaagca tatccgaaaa ccaaatggcg ccaagcctgg ttatgttatt tatgaaaacc
     1801 aaaagacgat tatcgtgaca ccagaagaag aaaaaattac agctatgaaa caaaacaggt
     1861 aatcaatgag tgtttctaga atcatatttg cgtactttcc cacaacagca attagttata
     1921 aatt
//
LOCUS       DAZKKZ010000167         1761 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.177, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000167 DAZKKZ010000000
VERSION     DAZKKZ010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1761)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1761)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1761
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.177"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            136..309
                     /locus_tag="ACG8LA_002999"
     CDS             136..309
                     /locus_tag="ACG8LA_002999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0205210.1"
                     /translation="MMKRLYYSLIITIGYLIVSNLGNMVFGISKEFSWTTTLWESLFF
                     FIFVFLLQNYRKK"
     gene            949..1422
                     /locus_tag="ACG8LA_003000"
     CDS             949..1422
                     /locus_tag="ACG8LA_003000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HFQ0205211.1"
                     /translation="MKFKTLLLKFVVLGISAVFILFGVLFYTQIATSEKGFNFDWQTT
                     LFVSVIYFALLLGIVIAYFLLKLLKKIEDNQAFSTQSLNILKKIERTILFIGFAFFGL
                     LPKFMKVADLDDAPGLMLVGIAVVFIPFAVYTLTSVLEKLLEHAILLKTDHDLTV"
     gene            1431..1658
                     /locus_tag="ACG8LA_003001"
     CDS             1431..1658
                     /locus_tag="ACG8LA_003001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0205212.1"
                     /translation="MAIIVNLDVVLAQKKMSVTELSEKVGITMANISILKNGKAKAIR
                     FSTLEKICQVLECQPGDLLTYKNDSNTIPEE"
BASE COUNT          589 a          273 c          264 g          635 t
ORIGIN      
        1 ttttcggaga attaaaaaat acaataaata actttagtta ctttaatgcg ttcttacttt
       61 atttttatat tatcattttt cttattcact tctttggttt atactattct tataaataaa
      121 aacgaggtat gtcctatgat gaaaagattg tactattcat tgatcataac gattggctat
      181 ttgattgtat caaatctagg aaatatggta tttggtatca gtaaagaatt cagttggact
      241 actacattat gggaatctct attctttttc atcttcgtat ttttgttaca aaattatcga
      301 aaaaaataaa catgtgccat ctatctgttg gcacatgttt taggatttat ggtacttttt
      361 attcggcaat ccattttatt tttctacttc ttcttaatac ctctaacact tttgatttat
      421 aaactaatcc aatgcatcta cttgcgctta ttaagctatt tcagctagat agtaccaccc
      481 catgcgtcaa tgcttgattt tccttttgta taacattgta taagcaataa aggacaaata
      541 agtggtgatt acaccaaacc attgaataag aaaaattctg atacgtaaat aaacatgaac
      601 ttgaaaaaat taatgaatcg gttagctact acgtagttgt cttttttctc atacagttct
      661 gttaacttac acttctcttc gctagataat aaaaaatcct ccaactgtat tgtccaatat
      721 aatcccaggc atctaaacta gcattataga agagacacac atagaatcta aaataactgg
      781 ttttaaatgt ttcttacaat caaaaaaagc tgttaaatgc actccacacc ttcatactct
      841 atcatttttt ataaacgata tatttttatt gtttttcgat aaaaaatagt tgttttacaa
      901 taattattct gctatatttt agctatcaaa gataaaagag ggataaaaat gaaatttaaa
      961 acattgctat taaaatttgt cgttttaggt ataagtgccg tatttatttt gttcggcgta
     1021 cttttttata ctcagatcgc tacaagcgaa aaaggattca attttgattg gcagaccaca
     1081 ttatttgttt ctgtcattta ctttgccctt ctcctaggga tcgttattgc ttatttctta
     1141 ttgaaactat tgaaaaaaat cgaagataac caagcttttt ccactcaaag cttaaacata
     1201 ctaaaaaaaa tcgaacgaac cattttgttt attggtttcg ccttttttgg cttacttcct
     1261 aaatttatga aagtagcgga tttagacgat gctccaggtt tgatgttggt aggaatcgct
     1321 gtcgtattca ttccttttgc agtatacaca ttaacaagcg tgctggaaaa actgcttgaa
     1381 catgcgattt tacttaagac agatcatgat ttgacagtgt gaggtgcgac atggcaatta
     1441 tcgttaattt agatgtagta ttagctcaaa aaaaaatgag tgtgactgaa ttgagtgaga
     1501 aagtgggcat tacgatggca aacatctcta ttctaaaaaa tggaaaagca aaagccatcc
     1561 gtttttccac tctcgaaaaa atctgccaag ttttggagtg tcaaccaggt gatttgttga
     1621 cctataaaaa tgactcgaat actataccag aagaataaaa taaagtagaa caaacagtaa
     1681 ataaaaaata atctgaatga tagatgtgtg agacttttag aagttattta cgtctattat
     1741 tcagattttt tatttggcgg a
//
LOCUS       DAZKKZ010000168         1680 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.178, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000168 DAZKKZ010000000
VERSION     DAZKKZ010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1680)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1680)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1680
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.178"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            64..972
                     /locus_tag="ACG8LA_003002"
     CDS             64..972
                     /locus_tag="ACG8LA_003002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate upper protein"
                     /protein_id="HFQ0205213.1"
                     /translation="MAKWNVILSTTEPYNYVGMIQVRQGNKNTEVMEATIVENGLPYD
                     LSECKVYFESVVGGKYPVQLETKIVDAKKGKINYIFDKYSMQCLHRQTANFIIFKGED
                     LIGTTQDFSYFVINAVSKTEGEMGSYWQSIEDLIADMTDFINENKGDFTDWMNERKEE
                     FERWRQEQEHSFQDWREGQESDYLAWFESIKDILKTIDPGGVMLAELTDARVDIQGVR
                     HASISERLLADMDYLYQKLRATLFTIEYGEIEVTDILQDDLFSDNHEVEKVGTVAFPI
                     EEGALIIATVDDPKQNVFTLEKVGVI"
     gene            972..1592
                     /locus_tag="ACG8LA_003003"
     CDS             972..1592
                     /locus_tag="ACG8LA_003003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0205214.1"
                     /translation="MAKTKRMMETDEKTGVQRQFFPITHASAVLGLEEIIAGEATVLS
                     VNGKIGAVVITKEDLGLENVLTELPYASEEDDGIITAEMYQKILNSGEGDYVLPVATI
                     DRLGGIKVGELLTIDETGKVSAVRQSDVNFSLELKEKLDSLKNYTAGENITIDEDGTI
                     SSTGGSGTGGVNQSYVDQKFQEAVNQAENYTNERIPNFTFEKIGEV"
BASE COUNT          602 a          246 c          377 g          455 t
ORIGIN      
        1 cagtattata gtgcaagtgc aatttcttcc attgtcatac caccaaaata gggaggtgat
       61 ttaatggcaa agtggaatgt catattaagt acaacagaac cctataatta cgtggggatg
      121 attcaagttc gacaaggcaa taagaataca gaggttatgg aagcgactat agttgaaaat
      181 ggtcttccct acgatttatc agaatgtaag gtatattttg aatcagttgt aggtgggaaa
      241 tatccagtcc aattagaaac aaaaattgtg gatgctaaaa aagggaaaat taactatatt
      301 tttgataaat attccatgca gtgtttacat cgacaaacag ccaatttcat tatatttaaa
      361 ggagaagact tgattggaac aactcaagac ttctcttatt ttgtcattaa tgctgtttca
      421 aaaacagaag gagaaatggg ttcttattgg caatcaatcg aagatttaat tgcggatatg
      481 acggacttta ttaatgaaaa taaaggcgat tttacggact ggatgaatga aaggaaagaa
      541 gaatttgaac gttggagaca agaacaggaa cacagtttcc aagattggag agaaggacaa
      601 gaatcagact atttggcatg gtttgaatca atcaaggata ttttaaagac gattgatcca
      661 ggtggagtca tgttagccga actaacggat gcgcgagtag atattcaagg agttcgtcat
      721 gcgtctattt cagagcgttt gctggcagat atggactatt tatatcagaa attgcgagca
      781 acgcttttca cgattgaata cggggagatt gaagtgactg atattttgca ggatgatctc
      841 ttttcagata atcatgaagt cgaaaaagtt ggaactgtag cattcccgat tgaagaagga
      901 gccttgatca tcgcaaccgt tgatgatcca aagcaaaatg tgttcactct tgagaaagtt
      961 ggggtgatct aatggctaaa actaaacgaa tgatggaaac ggatgaaaaa acgggtgtac
     1021 aacgccaatt ctttccaatc acacatgctt ccgcagttct tgggttagaa gaaataatag
     1081 caggagaagc aacagtttta tctgttaatg gaaaaattgg agccgtcgtc attactaaag
     1141 aagatttggg attagagaat gttctcacag aattacccta tgcaagtgaa gaagatgacg
     1201 gcattatcac ggcagaaatg tatcaaaaaa ttttaaacag tggagaaggt gactacgtgt
     1261 tgccagttgc cactatcgac cgtttgggtg gcataaaagt tggtgaatta ttgacgattg
     1321 atgagacagg gaaagtctct gcagtcagac aatctgatgt caatttttcg ctggagttaa
     1381 aagaaaaact cgattcactg aaaaattata ctgctggaga aaacatcact attgatgaag
     1441 atggaacaat tagttctaca ggtggtagtg ggactggtgg tgtcaatcag tcatatgtag
     1501 atcaaaaatt ccaagaagct gtaaatcaag cagaaaatta cacaaacgaa agaattccaa
     1561 attttacttt tgaaaaaatt ggggaggtat agagaatgac agatatcgta aaaataaaac
     1621 aaagcaatgt acaggtttat ccacaaactc attggaatgc tatagaaggc aaaccaacaa
//
LOCUS       DAZKKZ010000169         1664 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.179, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000169 DAZKKZ010000000
VERSION     DAZKKZ010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1664)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1664)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1664
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.179"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            131..505
                     /locus_tag="ACG8LA_003004"
     CDS             131..505
                     /locus_tag="ACG8LA_003004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HFQ0205215.1"
                     /translation="MYLKITEQAQERLQKYIDEGATVILDLDDGVGEYSKMGVCSLDT
                     SFRLLLLDKEQRKNDYKLQLDSDIGDVYIKDYSKMYMDEHMTLSLDPRLGVFTLESPS
                     GSLDSHVQLVDLRPEKFSGIKQ"
     gene            complement(619..1248)
                     /locus_tag="ACG8LA_003005"
     CDS             complement(619..1248)
                     /locus_tag="ACG8LA_003005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HFQ0205216.1"
                     /translation="MKIVFLHGLGQDEQSWKDVISYLPNSYSCKSLSLFNHLNSTDTA
                     TLDDLTKYIEVQLNQIKEPFILCGLSLGAVIALNYLATPSPYLKKVVLVAPQFESPNR
                     LLLTFQNIYFYCVPSKIFEKLGLSKKQTLTLLRSLETLDCKKQLRTSRLPKLILCGTK
                     DHANKPAAKRLYKLSTNGRLLFIKNGKHELNREKPEIMAQAMRSFIENS"
     gene            complement(1382..1454)
                     /locus_tag="ACG8LA_003006"
     tRNA            complement(1382..1454)
                     /locus_tag="ACG8LA_003006"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1419..1421),aa:Thr,seq:ggt)
BASE COUNT          584 a          240 c          283 g          557 t
ORIGIN      
        1 ctacactctg agatgtaaga aatatcataa gatatttctt acatcttttt gttttgagca
       61 ggactttaga taattttatt aatatatgct agcatgcttt tgtaagaaaa agaaagaggg
      121 cgtattagtt atgtatctta aaattacgga acaagcacaa gaaagattac aaaaatatat
      181 tgatgaaggc gcaacagtta tattggattt agatgatggc gttggggaat attctaaaat
      241 gggtgtttgc tctttagata ctagttttcg tttacttctt cttgataaag aacagagaaa
      301 aaatgattat aaactccaat tagatagtga tattggggat gtttatataa aagattattc
      361 aaaaatgtac atggatgaac atatgaccct ttctttagat ccacgtctag gtgtatttac
      421 tcttgaaagc ccaagtggtt ctttagacag tcatgttcaa ttagtagatc tacgaccaga
      481 aaaattctct ggaataaaac aataactttc tctctattgt ccataaaact agtctcaatc
      541 aagctgtatt gaaaaaacaa gacaacattc ttaccatggt aaataaaaag acgacacatt
      601 ttgtcgtctt tttttaaatt aactattttc gataaaagat cgcatagctt gtgccattat
      661 ttctggcttt tctctattca attcatgttt tccgttttta ataaagagta gccggccatt
      721 cgttgaaagt ttatataaac gttttgctgc tggtttattc gcatgatctt tggtaccgca
      781 taaaatcaat ttaggaagtc gtgatgtacg aagctgtttt ttgcagtcta atgtttcaag
      841 tgaacgaagt agggtaaggg tttgtttttt agatagacct aatttttcaa atatcttaga
      901 aggtacgcag taaaaataaa tattctggaa agtaagcaat aagcgattag gagactcaaa
      961 ttgtggagcg actaaaacaa ccttttttaa atatggagaa ggagttgcaa gatagtttaa
     1021 agcaataaca gcgcctaaag ataatccaca taaaataaaa ggttccttta tctgattcaa
     1081 ttgtacttcg atgtatttgg ttaagtcgtc taaagtagca gtgtctgtgc tgtttaaatg
     1141 attgaacaat gaaagacttt tgcaagaata actattgggt agataagaga ttacatcttt
     1201 ccatgattgt tcgtcttggc ctagaccatg caaaaaaaca attttcatat tgctctcctt
     1261 tttatagtta tcatatagac tttctttgta ctattaaaat ataaacattc atttcttacg
     1321 tcataaaata aaaaaacagc gcagacacat tgttaaacca acatgttgca ctgtttaagg
     1381 aagccacttg ccgggcttga accggcgacc tcttccttac catggaagcg ctctaccagc
     1441 tgagctaaag cggcattatc attaatacaa ataataggat aacgaatatt aatgtatttg
     1501 tcaacagaat tttttcgaaa aaatgtgttt ctctaatagg aaaacagatt ttagaaaaaa
     1561 taaaaataac aaaaaatgcg aacggtttct ttgataatat aataaaaaaa ttcaaaaaaa
     1621 gtattgcgtt atttagaaga aattgatatt atattcatgt actt
//
LOCUS       DAZKKZ010000170         1654 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.180, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000170 DAZKKZ010000000
VERSION     DAZKKZ010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1654)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1654)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1654
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.180"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..1144
                     /locus_tag="ACG8LA_003007"
     CDS             <1..1144
                     /locus_tag="ACG8LA_003007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HFQ0205217.1"
                     /translation="NHEVKTIDADKKTVTVTSASDNETKEYPYDKLILSSGVKPNNLP
                     VPGADLENVYLMRGYNWATKIKEKLNDPAIKKIAVVGAGYIGIEAAEASRKAGKEVVL
                     LDVIDRPLGTYLDAEMTDILEQHLNENGIEVLTNAKIEAFTGNGKVEAIKTSEKEIPA
                     DLVIQAAGVKANTEWLKGIVDLDERGWIQTNEYLQTNLPDVYAVGDATLAYSIPARKK
                     MPIALATVARREARYVVKHLFEEVPNKPFGGVVGSSALSVFDYHFAASGLNSFTAAKA
                     GVDVRVSYYEDTLRPKYVPEEQGNPKVSIQLFSDPMTHQLLGGAVLSTYDVTGQGNVL
                     ALAIQNKLTLEELAEADFFFQPGFDRQWSMLNLAAQQALGEEPFVE"
     gene            1425..1654
                     /locus_tag="ACG8LA_003008"
                     /pseudo
     CDS             1425..1654
                     /locus_tag="ACG8LA_003008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          591 a          293 c          356 g          414 t
ORIGIN      
        1 taatcacgaa gtaaaaacga tcgatgccga taaaaaaaca gtaacggtta ctagcgcatc
       61 agataacgaa acaaaagaat atccttatga caaattgatt ttgagttctg gtgtcaaacc
      121 aaacaatctg ccagtaccag gagcagatct agaaaatgtc tacttgatgc gtggatacaa
      181 ttgggcaacc aaaatcaaag aaaaattaaa tgatccggct attaaaaaaa tcgctgtcgt
      241 aggtgcgggt tacattggga tcgaagcagc agaagcaagc cgaaaagctg ggaaagaagt
      301 cgtattgctt gatgtgatcg atagaccttt aggcacttat ttagatgctg agatgacaga
      361 tattttagaa caacacctaa atgaaaacgg tattgaagtt ttgacaaatg caaaaatcga
      421 agcttttact ggtaacggaa aagttgaggc aatcaaaaca agtgaaaaag aaatcccagc
      481 agatctagtc attcaagctg ccggtgtgaa ggcaaataca gaatggttaa aagggatcgt
      541 cgacttagat gaacgtggct ggatccaaac aaatgaatac ttgcaaacga atcttccaga
      601 tgtgtatgca gtaggagatg ctacacttgc ttattctatc ccagcacgca aaaaaatgcc
      661 gatcgcttta gcgactgttg cacgtagaga agcacgttat gtagtaaaac atctttttga
      721 agaagtacca aacaaaccgt tcggcggagt cgtaggttcc tctgcattaa gtgtctttga
      781 ctatcatttt gcagcaagcg gattgaatag ctttacagca gcaaaagcag gagtagatgt
      841 acgagtgtct tattatgaag atacgttacg accaaaatat gtaccagaag aacaaggaaa
      901 tccaaaagtg tccatccaat tattctcgga tccaatgacc catcaattgc taggaggagc
      961 agtattatct acctatgatg ttacaggtca aggaaatgta ttggcactag cgatccaaaa
     1021 caaactgact ttagaagaac tagcagaagc tgacttcttc ttccagccag gctttgaccg
     1081 acaatggagc atgttgaatc tagccgctca acaagcgtta ggagaagaac catttgtaga
     1141 ataagaaaac gaaatatttg aaaagaggtt gtgaaaaagc tgccttgcat caagtaataa
     1201 gaacagccaa gtaaaaacag cttcttatgt ttttaacttg gctggactta ttaccgcaga
     1261 tgcaagcttt tgaacaccgt ttattttcaa aaaagggact gtgacacgat ttgtgtaccg
     1321 acccccaaaa gttagaccaa aaaatctaac ttttggaggt cggtattttt tatggttaaa
     1381 tatacttttg aacttaaatt aaagatcgtt catgattatt tggatggcaa aggcgattgg
     1441 accgtaaaaa tccagatcaa gagattgaag cggaaatgct taaaattcgg gagaagcaca
     1501 aggattatgg ctgtttacgg atgaccaatg aactaagaaa ccgcggtttc tctatcaata
     1561 aaaagaaagt tcagcgcttg atcaagaagc taggaataaa agtaacggca tacacgcgta
     1621 aatcacgtcg ctacaattct tatcgaggaa aagt
//
LOCUS       DAZKKZ010000171         1594 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.181, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000171 DAZKKZ010000000
VERSION     DAZKKZ010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1594)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1594)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1594
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.181"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            155..316
                     /locus_tag="ACG8LA_003009"
     CDS             155..316
                     /locus_tag="ACG8LA_003009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HFQ0205218.1"
                     /translation="MQDKDKCINCGKCKKVCQMNKDSVENCNHLECIRCGRCKNACPV
                     DAISYGVRK"
     gene            335..>1594
                     /locus_tag="ACG8LA_003010"
     CDS             335..>1594
                     /locus_tag="ACG8LA_003010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFQ0205219.1"
                     /translation="MIKNAIAYITRKKNRTLIIFIILTIVLSCLYSCLTIMKSSNEIE
                     KALYESSNSSISITKKDGKYFNVNQFKDIEKLKEIEEKIIQYDGLAKLKDAKVVSGEQ
                     RINREDLSDEFKNVVSLEATNNTKRNILFSSGVFTIKEGKNIEENDKNSIIVHEEFAK
                     QNNLKLGDEVDLELLDIEKSGKIKSHKFKIIGIFSGKKQETYTGLSSDFSENMVFVDY
                     STSQEILNNSENNEIANKILMYSGSAESTDLALNKLKELKIDESKYFVEKDSNAFEES
                     LESVSGIKYIIKVMTYSIMLGGMVVLSLILILWLRERIYEIGIFLSIGTSKIQIIMQF
                     IFELIFISIPSIISSLFLGNVLLKVIVDGFINSEDSMISGGSLINNSSFMSNITTLGQ
                     SYLILISIIVLSVVFASSLMLIKKPKEI"
BASE COUNT          628 a          154 c          274 g          538 t
ORIGIN      
        1 ctgcgcaagg cttaccagcg agatagagat cgacgatttg ttgtttgaat tcttttgaat
       61 aggttcttcg ttgacgtctt ggcatgaaaa atcctccagt gtgtttttta ttattctaca
      121 caccttattt tttctgtcta gtctagtgta gccgattcag gataaggata agtgtattaa
      181 ttgtggaaaa tgtaaaaaag tttgccaaat gaataaagat tcagttgaga attgcaatca
      241 tctggagtgt atcagatgtg gacgatgtaa aaatgcttgt ccagtggatg caattagtta
      301 tggagtaaga aaatagaaag gagtagttag gaaagtgata aaaaatgcta tagcatatat
      361 tacaagaaag aaaaatagaa ctttaataat ttttatcata ttaactatag ttctttcttg
      421 cttgtattct tgtttaacaa taatgaaatc aagcaatgaa atagaaaagg ctttatatga
      481 aagttctaat tcttcaatat caataacaaa aaaagatggt aaatatttta atgttaatca
      541 atttaaagat attgaaaaat taaaagaaat tgaagaaaaa ataattcaat atgatggatt
      601 agcaaaacta aaagatgcta aagtagttag cggagaacaa agaataaata gagaagattt
      661 atctgacgaa tttaagaatg ttgtttcact cgaagctaca aataatacta aaagaaatat
      721 tttatttagt agtggagtat ttacaattaa agaaggtaaa aatatagaag aaaatgataa
      781 gaattcaatt attgttcatg aagaatttgc taaacaaaac aatctaaaat taggtgatga
      841 agttgatctt gaattactag atattgaaaa aagtggaaaa ataaaaagtc ataaatttaa
      901 aattataggg atcttttctg gtaaaaaaca ggaaacatat acaggattat cttctgattt
      961 tagtgaaaat atggtgtttg tagattattc aacaagccaa gagatattaa acaattcaga
     1021 aaataatgaa attgcaaata aaattttaat gtattctggt agtgcagaat ctacagactt
     1081 agccttaaac aaattgaaag agcttaaaat tgatgagtca aagtattttg ttgaaaaaga
     1141 ttctaatgcg tttgaagagt ctttagagtc agtgagtgga ataaaatata taataaaagt
     1201 aatgacttat tctattatgt tgggtgggat ggttgttctt tcattaatct tgattctatg
     1261 gttaagggaa agaatttatg aaataggtat attcttatct attggaacat ctaagataca
     1321 aattataatg caatttatat tcgagttaat attcatatcg ataccaagta taatatcttc
     1381 cttattttta ggaaatgtat tactaaaagt aattgtagat ggattcatta actcagagga
     1441 ttcaatgatt tccggtggaa gtttaataaa taatagtagt tttatgtcaa atataacaac
     1501 acttggacaa agttatttaa tattaataag tattattgtt ttatcagttg tatttgcttc
     1561 ttcattaatg ttaatcaaga agcctaaaga aatc
//
LOCUS       DAZKKZ010000172         1594 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.182, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000172 DAZKKZ010000000
VERSION     DAZKKZ010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1594)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1594)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1594
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.182"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            288..695
                     /locus_tag="ACG8LA_003011"
     CDS             288..695
                     /locus_tag="ACG8LA_003011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0205220.1"
                     /translation="MSYRVQLIISEDVESQQFGTNVINKVINPALSINAPLIPTALSF
                     SVTAVVSEIEDTEKIKIVEIEVLNKNEKQIFSTGEVSVSLPPQVNDINFNINARNVLV
                     EEAGEHYAVVKFNGTEIGRQIFDIKVNKPVEKN"
     gene            709..1110
                     /locus_tag="ACG8LA_003012"
     CDS             709..1110
                     /locus_tag="ACG8LA_003012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0205221.1"
                     /translation="MLDIVPSNTHRSGSLINFAAIFACASVILASPVVVDASSTPKTK
                     NDNQLVITTKNEINTISSNDGKIFDVINTVLKRKAEINIKYDEDLNLYFFVIKTTSEL
                     FSSDYDVLDTLDNVLSDYKYMGKSVVATLGE"
     gene            1112..1483
                     /locus_tag="ACG8LA_003013"
     CDS             1112..1483
                     /locus_tag="ACG8LA_003013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0205222.1"
                     /translation="MFDFNEYLSISKQIESDDKYNSKESYRRTAVSRAYYSAFKKSDE
                     YLKENYDIIYNGSSGKGSHQTVWNLFSTVKELNTLGIHNSGYRMLEKRKCADYIPNET
                     ITKTDMALMNREAEKIINKLT"
BASE COUNT          596 a          201 c          277 g          520 t
ORIGIN      
        1 ttgaggggaa gtacatatag ttgttgatat agttgctaat attgttagct aatttgttag
       61 taaaactgta tacgaattta gatagtaaaa aaacagtttg ttccttatat agaggcactt
      121 ttactactga ttaaatgtca gatatgctta caaatatact tataaatatg cttacaaaat
      181 tagctaatat ttccgttgac aaagctttgt tactattgtt aaactaaatt gactagcaaa
      241 agtgaaacat aaatttatta aataaatgta aaaattagga gaaatcaatg tcttatagag
      301 tacaattaat aatttcagaa gatgtagaaa gtcagcaatt tggcactaat gttattaata
      361 aagtaattaa tccagctctt tctattaatg cgcctttaat tcctactgct ttatcatttt
      421 ctgtaacagc tgtggtgtct gagatagagg atacagaaaa gataaaaata gtagaaattg
      481 aagttttaaa caagaatgaa aaacaaattt tttctacggg tgaagtatcg gtaagcttgc
      541 ctcctcaagt taacgatata aactttaata taaacgccag aaatgtcttg gttgaagaag
      601 caggagagca ttatgctgtt gttaaattta atggaactga gattggaagg caaatctttg
      661 atatcaaggt caacaaacca gtggaaaaaa attaaggaga cgatacggat gcttgatata
      721 gtaccatcaa atacacatcg gagtggtagc ttaataaatt ttgctgcgat ttttgcttgc
      781 gcatcggtaa ttctagcatc tccagttgtt gtggatgcaa gttctactcc gaaaactaaa
      841 aatgataatc aacttgtaat tactacaaaa aatgagatta acacaatttc aagtaatgat
      901 ggcaaaattt ttgatgtgat aaatacggtt ttaaaaagaa aagctgaaat caatataaaa
      961 tatgatgaag atttaaactt gtatttcttt gttatcaaaa caacatctga attgttttcc
     1021 tcagattacg atgttttgga tactctcgat aatgtattat ctgactataa atatatgggg
     1081 aaatctgtag tagcaacttt gggggaataa aatgtttgac tttaatgaat atttatctat
     1141 ttccaaacaa attgaatcag atgataaata taattctaaa gaatcttata gaagaactgc
     1201 tgtttcaaga gcatactaca gtgcttttaa aaaatctgat gagtatttga aagaaaatta
     1261 tgatattatt tataatggaa gtagcggaaa aggaagccac caaaccgttt ggaatttgtt
     1321 ttcaacagtt aaggaattga ataccttagg aatacataat agtgggtata gaatgttaga
     1381 gaaaagaaaa tgtgctgact atattcctaa tgaaaccatt acgaaaacag atatggcgct
     1441 gatgaatcga gaagcagaaa aaataataaa caaactcacc taatgaattt caagcgagtt
     1501 tgtttgttat ttttttattt aatctttgta tctttctgga tcaacgaaag tatactttat
     1561 atagtcataa cgccgatgat cgctacgtgc gtcc
//
LOCUS       DAZKKZ010000173         1590 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.183, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000173 DAZKKZ010000000
VERSION     DAZKKZ010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1590)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1590)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1590
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.183"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            378..>1590
                     /locus_tag="ACG8LA_003014"
     CDS             378..>1590
                     /locus_tag="ACG8LA_003014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HFQ0205223.1"
                     /translation="MKLFVGIDVSSEKLDVCFLTDDNQLSILSEISVANDIEGASFIR
                     ETILEFNNSYHFDQIVIGMESTSMYSFHPSMFFHEDEKLKKLNTLVTIENPFRVKQFS
                     RMFDENKTDRNDALRIADFLRIQRFTTSPIKEEKYMALQRLTRTRYQLIKQLIRTKQH
                     FLENLTYKCNTLAREMRDESTSLFSATLISLMTEDFTLDELAELPLEAFCDLLQEKGK
                     GRFKQPEKIAKAIQRAITMSYRLGALAQESINVVLSVLVREIRALEKNIKELDKAIEQ
                     VIVVIPEYQCLTSIPGVGKVYAAGLIAEIGQIERFEDQTKLAKYAGLSWKVNQSGNYQ
                     SQNTPLTKQGNRYFRYYLVEAANSVKNYLPEYKAFYQSKYKEVPKHQHKRALVLTARK
                     FTRLVDTLLRKH"
BASE COUNT          521 a          304 c          284 g          481 t
ORIGIN      
        1 taatagtttt tattcaaaat gtttctagat tataaaattt attgaataac acattcctaa
       61 cggaatttgt ttcgatattg tgtgatttct cagagtacaa tggatgtatg gaaaggatcc
      121 aacgggaatt tgctatttcc tcctgtagcg tttgtctacc ctgtttagtc tgttacccga
      181 accactgtta tcactaccaa ctcattagct gtttcgataa tggactagac tttcaaatag
      241 tagtttggaa ggcagcttct agctctttta tcaccgtatt ctattaggcg aggttgtggc
      301 tatacagtga gtttctggga aatcccacag tatcgaagca ttttccaaaa tttatatcga
      361 aaggaggtcc ttcttccatg aaattatttg tcggtattga cgttagctct gaaaaactag
      421 atgtttgttt tttaacagac gacaatcaat tgtctatctt atctgaaatc tctgttgcca
      481 atgacatcga aggtgcttca ttcatacgag aaacaattct tgaattcaat aacagctacc
      541 actttgatca aattgtgatt ggcatggagt caacgtccat gtacagcttc catccttcca
      601 tgttttttca tgaagatgag aaactaaaga agctcaacac acttgtaacg attgaaaatc
      661 cttttcgggt gaaacaattt agtcgcatgt ttgatgagaa taaaactgat cgaaacgatg
      721 cattaagaat cgctgatttc ttgcgtattc aacgattcac aacttcccct atcaaagaag
      781 agaaatacat ggccttacag cgtttaacac gtactcgcta tcaacttatt aagcaattga
      841 ttcgtacaaa gcaacatttt cttgaaaatc taacgtacaa atgtaatacg cttgctcgag
      901 aaatgcgaga cgaatcgacg agtcttttta gtgcaaccct catttcactc atgacggaag
      961 atttcacatt ggatgaactt gctgagcttc ctttagaagc tttctgtgat ttacttcaag
     1021 aaaaaggaaa aggccgtttc aagcaaccag aaaaaatcgc taaagcaatt caacgtgcaa
     1081 ttaccatgag ttaccgccta ggtgctcttg cacaagaatc aattaatgtt gttttaagtg
     1141 ttctcgtacg agaaatacga gcacttgaaa aaaatatcaa agaattagat aaagccatcg
     1201 aacaagtaat tgttgtcatt ccagaatatc aatgcttaac cagtattcca ggcgttggta
     1261 aagtctatgc tgccggttta atcgctgaaa ttggtcaaat cgaaagattt gaagatcaga
     1321 caaaattggc aaaatacgct ggattaagtt ggaaagtgaa ccaatctgga aactatcagt
     1381 cgcaaaatac acctctgaca aaacaaggaa atcgatattt tagatactac ttagttgaag
     1441 ctgccaactc tgtaaaaaat tatcttcctg aatacaaagc tttttatcaa agtaaatata
     1501 aggaggttcc aaagcatcaa cacaaacgtg cactcgtcct aaccgcaaga aaatttacgc
     1561 gtctggtgga tacgctacta cgtaaacacc
//
LOCUS       DAZKKZ010000174         1569 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.184, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000174 DAZKKZ010000000
VERSION     DAZKKZ010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1569)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1569)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1569
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.184"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            24..635
                     /locus_tag="ACG8LA_003015"
     CDS             24..635
                     /locus_tag="ACG8LA_003015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HFQ0205224.1"
                     /translation="MDDKQKMYEKNRKHSEALNFRVDKKTYLELTLIAKQRGISRADV
                     CRERLKGLKYEPPLLAEDDRVVLTKQLNQIGNNLNQAVKALNIIAKYFREESEDKKEK
                     SLHFSFDASRYNIFKDELANSIAKKLMISYPDDIFLESNRSAPSFFKLSEVEKEYFEY
                     WIEKQTRPGTKEEYSQKVDRNLIHSIQIIASLKDEVKQLWELL"
     gene            620..>1569
                     /locus_tag="ACG8LA_003016"
     CDS             620..>1569
                     /locus_tag="ACG8LA_003016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HFQ0205225.1"
                     /translation="MGATITSKGRKKNLSSLLQYAANPSKKEKCVAVSGINCSDDSEE
                     ALQEMNLVRTKMNKSKDIAQAFHVIHSFDKSTSKELSIDKMHEIAVEFAEKAFPNSQI
                     IVASHNDKDHFHSHLVINNINMETCKRLRIDPKDLELMRKINDQVLNEHGLESVNNEY
                     YENLEKRTNLYSNDPSKMKYGKINYQEFVQNAIEATLEKCEVNSFEDFSDHLAKEYNI
                     EVYQFSKTNNKLGYVLYKQGVNFYERRGELITLGRDKQSRKEKSQYVERTFSARKLGK
                     RYSFESVSEQLEKNLEESHIKNFFNMEREQVMSLISGVNY"
BASE COUNT          622 a          203 c          296 g          448 t
ORIGIN      
        1 aaaaaaatgt gaggggataa tcaatggatg ataaacaaaa aatgtacgaa aaaaatcgca
       61 aacatagtga ggccttaaat tttcgtgtcg ataaaaagac ttatcttgaa ctgacattga
      121 ttgcaaaaca aaggggaatt tctagagcag acgtttgccg tgagcggtta aagggactca
      181 aatatgaacc gccgttgtta gctgaagatg atagggtagt tttaaccaaa cagttaaatc
      241 aaattggtaa caatttgaat caagcggtaa aggcattaaa tatcattgct aaatatttta
      301 gagaagaatc tgaagataaa aaagaaaaga gcctacattt tagttttgat gctagccgtt
      361 acaacatttt taaagatgaa cttgcgaata gcatagcaaa aaagttgatg attagttatc
      421 cagatgacat ttttttggag tccaatcgga gtgccccctc tttttttaaa ttatcagaag
      481 tagaaaaaga atatttcgaa tattggatag aaaagcaaac tagaccgggt acgaaagaag
      541 agtattccca aaaagttgat cggaatttaa ttcactcaat tcagattatt gcaagtttaa
      601 aagatgaggt gaaacaactt tgggagctac tataacatcg aaaggacgca agaaaaattt
      661 atcctcgcta ttacaatatg cagctaatcc ttcaaaaaaa gaaaaatgtg ttgcagtctc
      721 aggaataaat tgtagtgatg atagtgagga agcactgcaa gaaatgaatt tagtacgtac
      781 caagatgaat aaatctaaag atatagcaca agcgtttcat gttattcatt cgtttgataa
      841 gagtacttct aaagagttaa gtattgataa aatgcacgaa atagctgtcg aatttgcaga
      901 gaaagctttt ccaaattcgc aaatcattgt tgcaagtcac aatgataaag atcattttca
      961 tagtcatctt gtcattaata atattaacat ggaaacatgt aaaaggttgc gtattgaccc
     1021 taaagattta gaactaatgc gaaaaattaa cgatcaagtc ctcaatgaac atggtcttga
     1081 atcagtgaat aatgagtact atgaaaactt agaaaagaga accaatcttt attcaaacga
     1141 tccttctaag atgaaatatg gaaaaattaa ttatcaagag tttgtgcaaa atgcgatcga
     1201 agcaacgttg gaaaaatgcg aagtgaattc ttttgaagat ttttcggatc atttggcaaa
     1261 agaatataac attgaagttt atcaattttc aaaaacaaat aacaaacttg gctatgttct
     1321 ttacaaacaa ggtgtaaatt tctatgagcg tagaggtgag ttaattactt taggaagaga
     1381 taaacaatct agaaaagaaa aaagtcagta tgtcgaacgt acttttagtg caagaaagtt
     1441 agggaaaaga tattcatttg aatctgtttc tgaacaactt gaaaagaatt tagaagaatc
     1501 acatataaaa aattttttta atatggaaag agagcaagtt atgtcgctaa ttagtggagt
     1561 aaattacaa
//
LOCUS       DAZKKZ010000175         1559 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.185, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000175 DAZKKZ010000000
VERSION     DAZKKZ010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1559)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1559)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1559
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.185"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..209)
                     /locus_tag="ACG8LA_003017"
     CDS             complement(<1..209)
                     /locus_tag="ACG8LA_003017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0097351 - toxin sequestering activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0045927 - positive regulation of growth
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HFQ0205226.1"
                     /translation="MDTITPTNFKENIGKVLQEVVHSNSEIEITRDSKNGLNDGVIMI
                     SKRKWELLQEELYLQRTGTWAYVSD"
     gene            complement(308..622)
                     /locus_tag="ACG8LA_003018"
     CDS             complement(308..622)
                     /locus_tag="ACG8LA_003018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0205227.1"
                     /translation="MAEENKVVPFETLVINKEEFEQLFLDFFIQYDMIYDFSSSLDLF
                     ELEAEIIENSREKNGKIIISVEKFNELFSQTFEIDPDYYQPQEVFREFRNKIIGFSQT
                     TK"
     gene            complement(690..1184)
                     /locus_tag="ACG8LA_003019"
     CDS             complement(690..1184)
                     /locus_tag="ACG8LA_003019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0205228.1"
                     /translation="MFKVYFPFQWLVKGILLVLLGLILFGSYLTIKARHFPEEKPIKI
                     VTKDLKIGETYQADGVELTFKNIEVTEKRNEFAQHDRVLQVTYTLINDTENPIRPQQW
                     SIENKDGEELYEYDMILDNPEYIESGKEETVNYYYELPIERQDYQIVVRRENGYIVGL
                     PFTL"
     gene            complement(1177..1491)
                     /locus_tag="ACG8LA_003020"
     CDS             complement(1177..1491)
                     /locus_tag="ACG8LA_003020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0205229.1"
                     /translation="MNYPYFKVSASEETKEIFNNFYNQNKGVFGSKANMFRVMVSNLP
                     VLASPSNNKFNDSESIKFEQKISELESMISNEVIEKLDDIDQKLSYSLKNKYKTEEKK
                     DV"
BASE COUNT          477 a          289 c          191 g          602 t
ORIGIN      
        1 aaatcagata cataagccca tgtacccgtt cgttgtaaat aaagttcttc ttgtaacaac
       61 tcccattttc tcttagaaat cataatgacg ccatcgttca atccattttt agaatcccta
      121 gtaatttcta tttcagaatt tgaatgaact acttcttgca acactttacc tatattttct
      181 ttgaagtttg ttggagtaat agtatccaaa atgaatacct ctcttctcta tacctctatt
      241 atgaagtgcc cataaaataa agcaagcgtt gaggaataat tctatcaaca cttgctttat
      301 taagctttca ttttgtagtt tgactaaaac caataatctt atttctaaac tctcgaaaaa
      361 cttcttgtgg ttgataatag tctggatcta tttcaaatgt ttgtgagaat aattcattga
      421 atttttctac tgaaataatg attttaccat tcttctctcg actgttttct attatttctg
      481 cttctaattc aaataaatct agtgacgaac taaaatcata aatcatgtca tattgaataa
      541 aaaaatcaag aaaaagttgc tcaaactctt ccttatttat cactaatgtt tcaaacggaa
      601 caactttatt ttcctcagcc attctcccag ttccattttc aaaaatcaca aaactgatat
      661 taccttaaaa actactaaca aaataaaact tataaagtaa atggcaaccc aactatgtaa
      721 ccattctctc tacgtactac gatttggtag tcctgccttt caatcggtaa ttcataatag
      781 taatttactg tttcttcttt gccactttca atatactctg gattatccaa tatcatatca
      841 tactcataaa gttcttcacc atccttattt tcaatcgacc attgttgtgg acgtatcgga
      901 ttttctgtat catttataag tgtataggtc acttgtaata cacgatcatg ttgtgcaaat
      961 tcatttcttt tttcggtcac ttcaatattt ttaaatgtta gttcaacccc atctgcctga
     1021 taagtttcac ctatttttaa atcttttgtt acaattttta ttggcttttc ttctggaaaa
     1081 tgtctggctt taattgttag ataacttcca aaaagaatca atcctagtag cactaaaaga
     1141 attcctttaa cgagccactg aaacgggaag taaactttaa acatcttttt tctcctccgt
     1201 tttgtatttg ttttttagag aatacgataa cttttgatca atgtcatcaa gcttttcaat
     1261 tacttcatta cttatcattg attctagttc tgaaattttt tgttcaaatt taatgctttc
     1321 agaatcatta aatttattat ttgatggact agctaacact ggtaaatttg aaaccataac
     1381 acgaaacata tttgccttgg aaccaaaaac tcctttgttt tggttgtaaa aattgttgaa
     1441 tatttcttta gtttcttctg aagccgagac tttaaaatat ggatagttca tttttttctt
     1501 ccacctttct ttttttggga gggagtctgt agggagcttg ctccctcaga gatttaccc
//
LOCUS       DAZKKZ010000176         1555 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.186, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000176 DAZKKZ010000000
VERSION     DAZKKZ010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1555)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1555)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1555
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.186"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            132..344
                     /locus_tag="ACG8LA_003021"
     CDS             132..344
                     /locus_tag="ACG8LA_003021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014834536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0205230.1"
                     /translation="MAVWQIQLKERGAYGLISLSDVLCRKEMPDLFSLDQIIAIIGAA
                     AVVITAVAKASDSILAWLKFKKEQKK"
     gene            506..1024
                     /locus_tag="ACG8LA_003022"
     CDS             506..1024
                     /locus_tag="ACG8LA_003022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000357244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfbU family protein"
                     /protein_id="HFQ0205231.1"
                     /translation="MDKFNRLTLINQFEILKALNPNEEKYYAEKIEILTEGYEYHYSE
                     IFENISDPLPEEDSRFVLDILNMYRDITFSKNKLKDINSIDNYYIQFKGFDFNSSTEF
                     KLALYAQFFIEKLNRFQEIVEDSDFNTFNSHKPMRGTYIKFLENYNDLKSTNNYQFGN
                     LSYEMISKVLSL"
     gene            1031..1543
                     /locus_tag="ACG8LA_003023"
     CDS             1031..1543
                     /locus_tag="ACG8LA_003023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0205232.1"
                     /translation="MKLNSINDLFAIIGVIANILFSCLNFRFTQKNKKNKLSIEQMKK
                     DIETDLKNDHKERRKIEEYTSLMEKCKATDAIFSFLRKSDEIITRENIDLENEISKLE
                     SIFSDINSLKYLIVEENSDSFLEFEKYLTDLIDNRNNELMRQNIARFLTKLVSEWKSI
                     ISQNMDKLRY"
BASE COUNT          611 a          181 c          242 g          521 t
ORIGIN      
        1 aaaacactat atattccgaa aagtgagtat ctccattcat aaaataatca acatatttaa
       61 aaaatctaat tagctttttt agtcaatcta aagttcttta ttctatgata taatgttact
      121 gtagaaagtt tgtggcggtt tggcaaatcc aattgaagga gcgtggtgcc tatgggctta
      181 ttagcttatc ggacgtactc tgtagaaagg aaatgcctga tttgttctca ttggatcaaa
      241 tcattgctat tatcggagca gcagcagtag ttattactgc cgtagcgaaa gctagcgatt
      301 cgattttagc ttggttaaag ttcaaaaaag aacaaaaaaa atagagccgt ctcaactttt
      361 ggcgaggtag acgagctcta aagctttatt tacatgccat ccgctttgaa cggactacac
      421 tgggcatgtg acagcatgcc ctttcattta tattatatct cattctttta tataatgaaa
      481 gtaaataaat catggaggat aaaatatgga taaatttaat agattaacat taataaatca
      541 gtttgaaatt ttaaaagctt taaatcctaa cgaagaaaaa tactatgctg aaaaaataga
      601 aatactaaca gaaggttacg aatatcacta tagtgaaata tttgaaaata tttctgatcc
      661 attgccagaa gaagattcgc ggtttgttct agacatatta aatatgtata gagatattac
      721 ttttagtaaa aataaattaa aagatataaa ttcaattgat aattattata tacaatttaa
      781 aggttttgac tttaatagct ctaccgaatt taagttagca ctttatgcac aattttttat
      841 tgaaaaatta aataggtttc aagaaatagt tgaagatagt gattttaaca cttttaatag
      901 ccataaaccg atgagaggta cttatataaa atttctcgaa aattataatg atttaaaatc
      961 taccaataat tatcaatttg gaaacttgtc ttatgagatg ataagtaaag ttctaagttt
     1021 gtgatgataa atgaaattaa atagtataaa tgatttattt gctattatag gtgttattgc
     1081 taacatactt ttttcgtgtt tgaattttag atttactcaa aagaacaaaa agaacaaact
     1141 cagtatagaa caaatgaaaa aagacattga aactgattta aaaaatgacc ataaagaaag
     1201 aagaaaaatt gaagaatata cttctttaat ggaaaagtgt aaagcaactg atgcaatttt
     1261 tagcttttta agaaaaagtg atgagataat cacacgtgaa aatatagatt tagaaaatga
     1321 gattagtaaa cttgaatcta tcttttccga tataaattct cttaagtatt taatcgtcga
     1381 agaaaattcg gatagctttt tagaatttga aaaatatcta acagatctta tagataatag
     1441 aaataatgaa ttaatgagac aaaacattgc aagattcctt actaaattag tttctgaatg
     1501 gaaaagtatt atttctcaaa atatggataa attaagatat taaggatgtt agttt
//
LOCUS       DAZKKZ010000177         1545 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.187, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000177 DAZKKZ010000000
VERSION     DAZKKZ010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1545)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1545)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1545
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.187"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            2..400
                     /locus_tag="ACG8LA_003024"
     CDS             2..400
                     /locus_tag="ACG8LA_003024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HFQ0205233.1"
                     /translation="MTIFETVVTDVGIEAEVFRKEKIMILFGDEAPETLTDYCYKIEL
                     NQVRKEITCDMKLCFDKQMYVITAVGDVVQTNLNELGHITIKFDGSHEPELPGTMYVE
                     DKEMPHLRKGTIIKIDQEDQNGGKLYGNHA"
     gene            384..1079
                     /locus_tag="ACG8LA_003025"
     CDS             384..1079
                     /locus_tag="ACG8LA_003025"
                     /EC_number="4.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HFQ0205234.1"
                     /translation="MEIMLDTANTKSIYSCQQFLNLTGVTTNPTILKKEGASNFFSHM
                     KEIKKIIGQIPIHIQTIGRTEEEMIEDARVIIEELGKDTFIKVPVNQAGLQAIKKLKK
                     EGYLITGTAIYTELQGYLAINNGADYIAPYYNRMQNQGIDAMKVIDSLRTEIERTQRP
                     TKILAASFKNCEQVTTAIRSGAHAITLGKELLDQVLEMPSIDKAVRGFQEDWVQTFQA
                     ETIGELKKVADYF"
BASE COUNT          583 a          223 c          305 g          434 t
ORIGIN      
        1 gatgacgatc tttgaaacgg ttgtaacaga tgttggtata gaagcagaag tattcaggaa
       61 agaaaaaata atgattttat ttggagatga agcaccggaa acattaacag attattgtta
      121 taagattgaa ttgaatcagg taagaaaaga aataacttgt gatatgaagc tctgttttga
      181 taaacaaatg tatgtaatca cagcagtagg agatgttgtc caaactaatt tgaatgaatt
      241 aggacatatc acgataaaat ttgatggatc tcatgagccg gaacttccag gaacaatgta
      301 tgtagaagat aaggaaatgc cgcatttaag aaaggggaca atcattaaaa tcgatcaaga
      361 ggatcagaat gggggaaagc tatatggaaa tcatgcttga tacagcaaat acaaaaagta
      421 tttattcttg tcaacagttt ttgaatttaa caggcgtaac aacaaatcct acaattctga
      481 aaaaagaagg agcgtcaaac ttcttctcgc atatgaaaga aatcaaaaaa ataatcggac
      541 agattcctat ccatattcag acaataggaa gaacggaaga agaaatgata gaggatgctc
      601 gagttatcat agaagaactg ggaaaagata cgtttatcaa ggtgccggtg aatcaagcag
      661 gccttcaagc gatcaaaaag ttgaaaaaag aaggttattt gattaccggt acagctattt
      721 acacagaatt acaagggtat ttagctatta ataatggagc agattatatt gcaccttatt
      781 ataacaggat gcaaaatcaa ggcattgatg ctatgaaagt gattgattcg ttgcggactg
      841 agatcgaacg tacgcaaaga ccaacaaaaa tattagcagc tagtttcaaa aattgtgaac
      901 aagtcactac agccattcga tctggagctc atgcgataac gttaggtaaa gagctactag
      961 atcaagtatt agagatgccc tcgattgata aagcagtgag gggcttccaa gaagattggg
     1021 tgcaaacttt ccaagcagaa acgattggtg aactaaaaaa ggtcgctgat tacttctgaa
     1081 tcaatttctc cataaaataa acgatagcct tctcgaaaac tcgaggaggc tatctgacga
     1141 ttcaatattc attaatttaa agtttgggtg actattacta actattactt atttctcatt
     1201 taaacgatgt attccctaac ctctaataca tccttgtaac tctgaagtta cgccagtttt
     1261 gaataaattt cataaaaaca aatgaaaagt gtcgcataaa aatatctttc gtgtttctct
     1321 agtataacag aataagaaga acaagtccag aagggatatt tttagtcttt tttaaaataa
     1381 cttttcagtc gagtttgagt ttatgatagt tgtttttgaa gcgatacggc aagtgaaaaa
     1441 atagggaagc atgaaagaat ctacttaatg gcgcattgat tcatgtgata gaaataaaaa
     1501 acttttttaa attatatcct catgattgta acaaatccag tgatt
//
LOCUS       DAZKKZ010000178         1537 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.188, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000178 DAZKKZ010000000
VERSION     DAZKKZ010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1537)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1537)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1537
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.188"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(52..1518)
                     /locus_tag="ACG8LA_003026"
     CDS             complement(52..1518)
                     /locus_tag="ACG8LA_003026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HFQ0205235.1"
                     /translation="MEKQQDKGFFGQPKGLSTLFFTEMWERFSYYGMRALLIYYMYDT
                     VANGGLGLPRATALAIMSIYGSLIYMSSIVGGWVSDRVLGAKRTVFFGGVFIMLGHIV
                     LALPFGVSTLFVSMALIIIGTAFLKPNVSGMVGHLYSKTDLRRDAGFSIFYMGVNLGA
                     LLAPLIVGTIGQEYNYHLGFSLAAIGMFFGLLQYIIQGRKTLDGVGTTPPNPLTTEER
                     KGFIRNLIIALVVIAAVFGGAQLTGHLTIDFFVNTISVLGIILPLYYFIKMLTSKDVT
                     AEEKPRVWAYIPLFLAAIIFWSLQEQGSSILALFASERTQSTLFGVTIQASWYQSLNP
                     IFIFILTPVFVTMWTKLGERQPSTVVKFSLGLLFAGLSYLLLMLPGMLYGTSGKVSPL
                     WLLGSFFIVVIAELCLSPVGLSVTTKLAPRAFESQTIAIWFLADASSQAINAQIARFY
                     TPGTESAYFGIIGAVAIVGGILLFTVKEPIKKLMGSIH"
BASE COUNT          501 a          326 c          289 g          421 t
ORIGIN      
        1 aaaaaacagg aactgctgca aataagcaat tcctgttttt atgttcattg attaatgaat
       61 agagcccatt agttttttga ttggttcttt cacagtaaat agcaagatac caccgacgat
      121 tgctactgca ccgataatac cgaagtaagc agattctgtt cccggtgtgt agaagcgtgc
      181 aatttgtgca ttgattgctt gtgaagaagc atcagctaag aaccaaatag cgattgtttg
      241 tgattcaaat gctcgtggtg ctaattttgt tgtcacagac aaaccaactg gtgaaagaca
      301 caattcagca ataaccacga tgaagaaact tcccaacaac cacaatggac ttacttttcc
      361 acttgtacca taaagcatac ccggcaacat caatagcaag tacgataatc ctgcaaataa
      421 aagtccaaga gagaatttca ctactgtaga tggttgacgt tcaccaagtt tcgtccacat
      481 cgttacgaat actggtgtca gaataaagat gaaaattgga ttcaatgatt gataccagct
      541 tgcttggatc gttacaccaa atagcgtaga ttgtgtacgt tcactagcaa ataaagctaa
      601 gatagatgaa ccttgttctt gtaatgacca gaaaatgatt gctgcaagga ataatgggat
      661 ataagcccat actcttggtt tttcttcagc agttacatct tttgaagtca gcattttgat
      721 aaagtaatac aacggtaaga taatccccaa tacactgatt gtattgacaa aaaagtcaat
      781 tgtcagatga ccagttagtt gtgccccgcc gaatactgca gcgataacaa caagtgcgat
      841 gatcaagtta cggatgaatc ctttacgttc ttcagttgtc aaaggattcg gcggtgttgt
      901 acccactccg tctaatgtct tgcgtccttg gatgatgtat tgtaataatc caaagaacat
      961 cccaatagca gctaaagaga accctaaatg atagttatat tcttgaccga ttgtaccaac
     1021 gattagtggt gctaataatg cccctaagtt gacacccatg taaaaaatcg aaaatcctgc
     1081 atctcttcgc aagtcagtct ttgaataaag atgtccgacc atgccagaaa catttggttt
     1141 caaaaaggcg gttccgataa taatcaatgc catcgaaaca aacaatgtac ttacaccaaa
     1201 tggtaaagcc aagacgatgt ggccaagcat aatgaaaact ccaccgaaga atacagtgcg
     1261 ttttgctcct aacactcggt cagataccca tccgccgacg atactagaca tgtagatcaa
     1321 agatccgtag atcgacatga tagctaatgc tgttgctcgt ggtaatccaa gtcccccgtt
     1381 ggcaactgta tcgtacatat aatagataag taatgcacgc ataccgtaat aactaaatcg
     1441 ttcccacatc tcagtgaaga acaaagttga caatcccttc ggctgcccga agaagccctt
     1501 gtcttgctgt ttttccataa tctatacccc aattctt
//
LOCUS       DAZKKZ010000179         1445 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.189, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000179 DAZKKZ010000000
VERSION     DAZKKZ010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1445)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1445)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1445
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.189"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..390
                     /locus_tag="ACG8LA_003027"
     CDS             <1..390
                     /locus_tag="ACG8LA_003027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFQ0205236.1"
                     /translation="KDRKEICDDFKAVYQANSKEEANTFLSGMIEKWKKNYPKVTQSL
                     IENQDLLTFYDFPPSIRRTIYSTNLIESFNKQIKRYSRRKEQFQNEESLERFLVSIFD
                     TYNQKFLNRSHKGFQQVTDTLVSMFTE"
     gene            813..1445
                     /locus_tag="ACG8LA_003028"
                     /pseudo
     CDS             813..1445
                     /locus_tag="ACG8LA_003028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
BASE COUNT          512 a          263 c          251 g          419 t
ORIGIN      
        1 aaagaccgaa aagaaatctg tgatgacttt aaggctgttt atcaagctaa ctcaaaagaa
       61 gaagcgaata ccttcttatc cggcatgatt gagaaatgga agaaaaacta tcctaaagtg
      121 acgcagtcac tcatagaaaa ccaagactta ttaacttttt atgattttcc acctagcatt
      181 cgtagaacca tttactcaac caatctaatc gagtctttca ataagcaaat taaaagatac
      241 agccgtagaa aagagcagtt tcaaaatgaa gaatcactag aacgctttct agtcagcatt
      301 tttgatacat acaatcaaaa atttctaaac agaagccata aaggttttca acaggtaacc
      361 gatacattag tttcaatgtt tactgagtaa ctaattattt tgcaggagga caatttattt
      421 acacaaaatt attgacgctc cctgtttcaa agttagtaga gaaaatgtag ttatatattt
      481 aaatttttac cagaaagaaa tgaacacctt caattatcta aatctcgaaa atggttagat
      541 gtaatcatca ggaaaaacaa tcttaaacga attactattc atggtcttag acacacacat
      601 gctagcttgc ttttagcaag ctagtgcaaa tattaaagat gtgcaagagc gtttaggcca
      661 ctcttctatt caaatcatta tggatctata tattcatatt acagacaaaa gaaaagaaga
      721 aaccgtagcg caattcgcaa aatataggct ctataattta tgggactgat gaatcaaaat
      781 tgattcttca gtcccattgt tattttaggt atatgattcg tacattgaaa gagttgaaaa
      841 actatcttcc gaagccgtca aaaaggaccc tgccaaaagt attgatggtg gatgaatttc
      901 gttcgcacgc ttcaattgtg gataaaatga gctttatttg tgcggatggc gagactggaa
      961 aactcattga tattttgcct acacgaaaat tgtctcgatt aacacactat tttagtcgct
     1021 gtgcaaatcc tgaagcggtg gaatatttag tgacagatat gaacgccgcc tacttccaac
     1081 tgacaaaacg tgtcttacca aatgcgaaag tcgtcattga ttgttttcat atcatcaaac
     1141 atttgaatca ggcgttcaat gattttcgtg tacaagaaat gaaaagatta caccagttag
     1201 ggcaacgacg ggaagccgag aaagtgaaaa agaactggcg ctttcttcta aaaaaccgtc
     1261 aaaaaatcaa tcactatgat tacaaaacat ggcgcagttt tcgtgcacct aaatacccgc
     1321 tactcactga agcaatgatg attgatcgat tgctggcatt ttcaacgcct ttaaaggacg
     1381 cctatacttt tttccatgag ctgaccgaag cctttagaga caaggaatca gacttatttt
     1441 ttacc
//
LOCUS       DAZKKZ010000180         1418 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.190, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000180 DAZKKZ010000000
VERSION     DAZKKZ010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1418)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1418)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1418
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.190"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(182..1201)
                     /locus_tag="ACG8LA_003029"
     CDS             complement(182..1201)
                     /locus_tag="ACG8LA_003029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HFQ0205237.1"
                     /translation="MKKKITITAMSLLTALFLLPINGFAYTINNEFNLGANEGSSQVA
                     NNQYILLHETANETATGRNEAQYMQRSWTSAYTAYIVGDGGIVYQVGQPGYVQYGAGS
                     YANANSPVQIELQHTHDKATFEKNYKAYVELARDSAMKYGIPLTLDTPYNQPGIKSHL
                     WVTQNIWGDHTDPYGYLSEMGVSKEKLAYDLAHGFTDENPTTSENKPVIDPTRAGAAN
                     PTLTDGTNYAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELARVRADGIY
                     RADVNQAYNTSGNVGYHVSFNMRNFPNKKVYVMMRATNDPEGNTKGGAQDFHDKRWYL
                     NIPKR"
     gene            complement(1198..>1418)
                     /locus_tag="ACG8LA_003030"
     CDS             complement(1198..>1418)
                     /locus_tag="ACG8LA_003030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HFQ0205238.1"
                     /translation="NKTFEVLKWFALVIIPALATFVGLVGKALNWQYTDICVVIITGF
                     GAFLGSVLGVSNRTYKMFSAESEEGGNK"
BASE COUNT          402 a          295 c          255 g          466 t
ORIGIN      
        1 tgccacataa agccataaac aatcaaccag tagaatgtgt ggcaacaaac ctgttatcgc
       61 atagcttgga gtgtgactat tatgggtgat agtgaagata tgcgataaca tcactatttt
      121 atcgaatgat ttttatagtt gtcaatatag ttatgtaatg ctcctcaacg aggagctatt
      181 tttatcgttt aggaatattt aaataccaac gtttgtcatg gaaatcttgc gcaccgcctt
      241 tagtgtttcc ctctggatca ttcgttgccc gcatcatgac atagactttc ttattaggga
      301 agttacgcat gttaaaagat acatgatagc caacatttcc agaagtatta taagcttgat
      361 ttacatctgc tctataaatt ccatcagctc ttactcgagc taattctttc ccagtattgt
      421 aatccataat gaagatatac tcgtatttat agttagcaat gtgccatcca gctacatgca
      481 aatttgcatt ttcgatttct ccaaactgat caatgtgggc gtaattcgtt ccatctgtca
      541 gtgtaggatt agctgcacca gctcgtgttg gatcaatgac aggcttgttt tcagaagttg
      601 ttggattttc atcggtaaat ccatgagcta aatcatatgc taatttttct ttacttacgc
      661 ccatttcaga aagataaccg taaggatctg tatgatcgcc ccagatgttt tgtgttaccc
      721 ataaatgcga tttgattccc ggttggttat aaggagtgtc caacgttaat ggaataccat
      781 atttcattgc tgaatctcta gccaattcaa cgtatgcctt gtagtttttc tcaaacgttg
      841 ctttatcatg tgtgtgttgt aactcaatct gcacaggact gttggcatta gcatacgaac
      901 cagcaccgta ctgtacataa ccaggttgac cgacttgata aacaattccg ccgtctccca
      961 caatataagc agtataagcg ctagtccatg aacgttgcat atactgcgct tcattgcgtc
     1021 ctgttgctgt ttcattagcc gtttcatgca gtaaaatata ctgattattt gctacttgtg
     1081 agctaccttc atttgcgccc aaattaaatt cattgttgat agtataggca aatccgttaa
     1141 ttggcaataa aaaaagagcc gttaacaggc tcatcgcagt aatagtaatt ttctttttca
     1201 tttgtttcct ccttcttcgc tttcagccga gaacattttg taggttcgat ttgatacacc
     1261 caacacactc cctaaaaacg cgccaaaacc agtaatgatg acaacacaga tatctgtgta
     1321 ctgccaattg agcgctttac caactaaccc cacgaaagta gctagtgcgg gaataattac
     1381 cagtgcgaac cattttagta cttcgaacgt tttattat
//
LOCUS       DAZKKZ010000181         1352 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.191, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000181 DAZKKZ010000000
VERSION     DAZKKZ010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1352)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1352)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1352
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.191"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            11..1350
                     /locus_tag="ACG8LA_003031"
     CDS             join(11..452,452..1350)
                     /locus_tag="ACG8LA_003031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element ISEnfa3 family transposase"
                     /protein_id="HFQ0205239.1"
                     /translation="MRKYTFVFKKKVVSDYLNNEGGYKYLAHKYQINRTLVRHWVRIY
                     NYHGWEGLVGGGKSYTTKFKLDVIEYMETNGLSIQETAKKFNIGSNRTLSKWIEQYEE
                     GGASSLESQKRGRKISMNSKLNIPKKLKDESLEEEVIRLRAENAYFKKVRNLDSRTRF
                     EQEEIKVKTILQLKKEFKLNLLLSIAQLAKSTYYYWVKKLDKPDKYSKIKQEITAIVK
                     ESRNSYGYRRVTLALKMKGYTINHKTVRKLMSQMGLTCQIRIKRYKSYKGTVGKIAKN
                     VLKRNFSVDTPNKKWVTDVTEFKIKGRKIYLSPILDLFNGEIISYSISTSPTYKLIEE
                     MLQQAIKKKGTEGSLILHSDQGWQYQMPQYQKKLKENNIIQSMSRKGNCLDNSVIENF
                     FGVLKSEFFYREKFRSIEIFQSKLNEYIRWYNNKRIKLKLNGLSPVEYRKQSIK"
BASE COUNT          565 a          175 c          235 g          377 t
ORIGIN      
        1 ggtgcttttt ttgcggaaat atacatttgt ttttaagaaa aaagtagttt cagactattt
       61 aaataacgaa ggcggctaca aatatcttgc acataaatat caaataaatc gtacactggt
      121 tagacattgg gtaaggattt ataactatca tggttgggaa ggcttggttg gaggtggcaa
      181 aagctacact acaaaattta aacttgatgt tatagaatat atggaaacaa atggtctttc
      241 tatccaagaa actgctaaaa aatttaatat cggttcaaat agaactctaa gtaaatggat
      301 agagcaatat gaagaaggcg gtgcttcttc acttgagagc caaaaaaggg gcagaaaaat
      361 tagtatgaat tccaagctaa acattcctaa aaaacttaaa gatgagtctc ttgaagaaga
      421 agttattcgt ttaagagcag agaacgcata tttaaaaaag ttagaaacct tgattcaaga
      481 acaagatttg agcaagaaga aatcaaggtt aaaacaatcc ttcagctcaa aaaagaattt
      541 aaattgaatc tattactttc aattgcacaa ttagcgaagt caacttatta ttactgggta
      601 aaaaaattag ataagccaga taaatatagc aagataaagc aagaaattac agcgattgta
      661 aaagaatcaa gaaactctta tggttatcgt agagtcactt tagcgttaaa gatgaaagga
      721 tatacaatca atcataaaac agttagaaaa ttaatgtccc aaatgggact tacctgtcaa
      781 atccgaataa agcgatataa atcttataaa ggaacagtag gaaaaattgc caagaatgtg
      841 ttaaaacgaa atttttcagt agatacaccc aataaaaaat gggtgacaga cgtcactgaa
      901 ttcaagataa aaggaagaaa aatctatcta tctcctatac ttgatttatt taacggagaa
      961 ataattagtt atagtatatc aactagtcca acatataaac tgattgaaga aatgcttcaa
     1021 caagcaatta aaaaaaaggg aactgagggt tcactgattc tacattcaga tcaaggatgg
     1081 cagtatcaga tgccacaata tcaaaaaaaa ttaaaagaga ataacattat tcaaagcatg
     1141 tctagaaaag gaaattgctt agataattct gtaatagaaa atttttttgg tgtgcttaaa
     1201 tcagagtttt tttatcgaga aaaattccga tcaattgaga tatttcaaag taaattaaat
     1261 gagtatatta ggtggtataa taacaaaagg ataaaactaa agttaaatgg actatctcca
     1321 gtagaatatc ggaaacagtc cattaaatag tt
//
LOCUS       DAZKKZ010000182         1337 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.192, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000182 DAZKKZ010000000
VERSION     DAZKKZ010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1337)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1337)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1337
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.192"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..1337
                     /locus_tag="ACG8LA_003032"
     rRNA            <1..1337
                     /locus_tag="ACG8LA_003032"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          358 a          293 c          406 g          280 t
ORIGIN      
        1 gaaataatag taccgaagtt cctgatgtca cactgccgag aaaagcttct agtgagaaaa
       61 cagcggcccg taccgcaaac cgacacaggt agtcgaggag agaatcctaa ggtgagcgag
      121 agaactctcg ttaaggaact cggcaaaatg accccgtaac ttcgggagaa ggggtgctga
      181 tcatacgatc agccgcagtg aataggccca agcgactgtt tatcaaaaac acaggtctct
      241 gcaaaatcgt aagatgaagt ataggggctg acgcctgccc ggtgctggaa ggttaagagg
      301 agtgcttagc gcaagcgaag gtacgaattg aagccccagt aaacggcggc cgtaactata
      361 acggtcctaa ggtagcgaaa ttccttgtcg ggtaagttcc gacccgcacg aaaggcgtaa
      421 cgatttgggc actgtctcaa cgagagactc ggtgaaattt tagtacctgt gaagatgcag
      481 gttacccgcg acaggacgga aagaccccat ggagctttac tgtagtttga tattgagtgt
      541 ctgtaccgca tgtacaggat aggtaggagc cgtagaaatc ggaacgctag tttcgatgga
      601 ggcgctggtg ggatactacc cctgcgttat ggccactcta acccgcacca ctaatcgtgg
      661 tgggagacag tgtcagatgg gcagtttgac tggggcggtc gcctcctaaa aggtaacgga
      721 ggcgcccaaa ggttccctca gaatggttgg aaatcattcg aagagtgtaa aggcagaagg
      781 gagcttgact gcgagaccaa caagtcgagc agggacgaaa gtcgggctta gtgatccggt
      841 ggttccgcat ggaagggcca tcgctcaacg gataaaagct accctgggga taacaggctt
      901 atctccccca agagtccaca tcgacgggga ggtttggcac ctcgatgtcg gctcgtcgca
      961 tcctggggct gtagtcggtc ccaagggttg ggctgttcgc ccattaaagc ggcacgcgag
     1021 ctgggttcag aacgtcgtga gacagttcgg tccctatccg tcgcgggcgt tggaaatttg
     1081 agaggagctg tccttagtac gagaggaccg ggatggactt accgctggtg taccagttgt
     1141 tctgccaagg gcattgctgg gtagctatgt agggaaggga taaacgctga aagcatctaa
     1201 gtgtgaagcc cacctcaaga tgagatttcc catttcttta agaaagtaag atccctgaga
     1261 gatgatcagg tagataggtc aggagtggaa gtacagtgat gtatggagcg gactgatact
     1321 aatcgatcga ggactta
//
LOCUS       DAZKKZ010000183         1336 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.193, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000183 DAZKKZ010000000
VERSION     DAZKKZ010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1336)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1336)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1336
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.193"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..183
                     /locus_tag="ACG8LA_003033"
     CDS             <1..183
                     /locus_tag="ACG8LA_003033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0205240.1"
                     /translation="LDGIKFSLIPTTENIIPKKLYYIFSSEKHTSMKPCIFDWQWLID
                     AVLDVKCSKYNITLGC"
     gene            186..359
                     /locus_tag="ACG8LA_003034"
     CDS             186..359
                     /locus_tag="ACG8LA_003034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0205241.1"
                     /translation="MSMLVRKLPLSVREFLFYLVCLIASGFKLIEHIFIFAYVLAMIA
                     FLSGGWLIIYLLS"
BASE COUNT          511 a          144 c          180 g          501 t
ORIGIN      
        1 ttagatggta ttaaatttag cttgatccca acaactgaaa atattattcc gaagaaatta
       61 tattatatct tttcatctga aaaacatact tcaatgaagc cttgtatttt tgattggcaa
      121 tggttgattg atgctgtatt ggatgtaaaa tgttcaaaat acaatattac tttggggtgt
      181 taattatgag tatgctagtt agaaaattac cattatctgt aagagaattt ctattttact
      241 tggtctgctt aatcgcatca gggtttaagc tgatcgaaca tatttttatc tttgcttatg
      301 tattagcaat gatcgcattt ttatctggcg gttggttaat tatttatttg ttaagctaag
      361 ttttagatca aaaataatta ataaattaaa cgataaaata accgttaata aatgtaatga
      421 aaggacaacg tctaacaatc agcttgtaat aagattataa aataacataa tattaaaata
      481 agtgcttttt aaaggacaaa ttaagtgtat caacataaac gtgtatatgt atatgtttat
      541 gttgatactt tttttgtctt aattttttta tttttaaaat tctatttact aatgctgtat
      601 agatagtgat cagaaaaaac aaaatagcga ggttaagcta tttattagtt catatattat
      661 attcagatta atatgatcca gtattaatct gaaggcaaaa ccaatatatt tctacggatt
      721 cttgtaaact atttaaattt ccctgctaat aaaataacaa aaatagaata tttagctttt
      781 ttataccatt ttacgataac atgattttat ttgtaatatt aaaacattta aattttgaat
      841 tattttttca aattagatta attaatatcc ttataaaaga gcataattaa tggtttttac
      901 atcgttattt attgatatta atctcatcca aaaaaatgaa agcgcatact tttatgagtg
      961 attgaatgtg attttaatac atataccaat taaaagaaaa ctttttagat ttttacttac
     1021 aaatttataa aaaaacaaga taattgatac tttgattttg cgaacatttt atctttccgc
     1081 ctaattcagc tttaatatca tgattatatc agtaaaaaat cgttttttta gctaatttaa
     1141 gcatcaaata attattctta atcaatgaaa aaataacgaa taaattaatt ttgggaatag
     1201 gtaaaaactt gttcggtttc tggataaaaa taacatgaaa aaggaaatat aaaataacat
     1261 ggagcgtggg aggaataaag aaattttaca cgcaaggtgc gtaggaatgt aaagaaactt
     1321 aacacgaaac aaaagt
//
LOCUS       DAZKKZ010000184         1330 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.194, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000184 DAZKKZ010000000
VERSION     DAZKKZ010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1330)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1330)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1330
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.194"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            82..1161
                     /locus_tag="ACG8LA_003035"
     CDS             82..1161
                     /locus_tag="ACG8LA_003035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006908283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HFQ0205242.1"
                     /translation="MTQNHDNTVSRKGKHLTYSERCQIAILKKENYSNRQVADVLGCV
                     PQTINNEIKRGTVTQLNRQNQNGKVYDYYHDVYDADAGQAAYEKNRLNCGRRPLWADT
                     DAFIEWADDMMLLEKWSPDVVVGFARKHELFDPAIIPGTTTLYQWIDRGIMKTKNMDL
                     LEKLSRKPKSSRHGNRPNKRVLGKSIEERPEAVGTRKTFGHWEVDTVVGNKTKSDAVL
                     LTLVERQTRFEVILKLAGKDAESVNQAVRQLRERAGAYFGQLFKTVTSDNGSEFAGLH
                     DALQDVANIYFSHPYASWERGTSENQHKLIRRFIPKGSPIGNVSENQILRIQRWMNDY
                     PRKILGYATPHDTFVQAFRQERLTA"
BASE COUNT          358 a          355 c          368 g          249 t
ORIGIN      
        1 atttggaaat aaaaaaacgc cacgtgaatt ccatgttata ttgaagttac cacaactctc
       61 aatagacaag gatgaattca catgacgcaa aaccatgata acacagtttc acgcaaggga
      121 aaacacctaa cctactcaga acgttgccaa atcgccatcc tgaaaaagga aaactattcc
      181 aaccgtcagg ttgcggatgt cctgggctgc gtgccgcaga ccataaacaa cgaaatcaaa
      241 cgcgggaccg ttactcagct taaccgccag aatcagaacg ggaaggtcta cgactattat
      301 catgacgtct acgacgccga tgccgggcag gcggcctacg agaagaaccg cttgaactgc
      361 ggcagacggc ccttatgggc cgacacggac gccttcattg aatgggcgga cgacatgatg
      421 ctgttggaaa aatggtcccc ggacgtggtg gtgggctttg ccagaaaaca cgaattgttc
      481 gacccggcca ttatccctgg gaccaccacc ctctatcagt ggatcgaccg tggcatcatg
      541 aaaacgaaga atatggacct gctagaaaaa ctgtcccgca aaccgaaatc gtcccgtcat
      601 ggcaaccgcc cgaataaacg ggtgctaggg aaatccattg aagagcgccc ggaggcggtt
      661 ggtacccgga aaaccttcgg ccattgggaa gtcgacacgg tcgtaggaaa caagaccaag
      721 tcggatgccg tgctgctgac gttggtggaa cggcagacac gcttcgaggt cattctgaag
      781 ctggccggga aggatgccga atcggtcaac caagcggtcc gacagctgag agaacgggct
      841 ggtgcgtact tcggccagct gttcaagacg gttacctcgg acaacggctc ggagttcgcg
      901 ggactgcacg atgccttgca ggatgtggca aacatctact tcagccaccc ctatgcttcc
      961 tgggagcgcg ggacgagcga aaaccaacac aagctgattc gccgtttcat ccccaagggc
     1021 agcccaatcg gcaacgtgag cgaaaaccaa atcttgcgga ttcagcgttg gatgaacgat
     1081 tacccgcgaa agattttggg ctatgcaacg ccgcatgaca cgttcgtcca ggcatttagg
     1141 caggaacggt tgacggcttg acacgtgggc ccttgacaac gagcctccct cggcatggct
     1201 tgtgtctgga aagctggccg gggccagcca gtcgggagac taccatgcct cagctcattg
     1261 tcaagggccc actcgattag aaaaattaga cggttggtgg taacgagcaa ccgggtcacc
     1321 atgggtggct
//
LOCUS       DAZKKZ010000185         1316 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.195, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000185 DAZKKZ010000000
VERSION     DAZKKZ010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1316)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1316)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1316
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.195"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            82..>1316
                     /locus_tag="ACG8LA_003036"
     CDS             82..>1316
                     /locus_tag="ACG8LA_003036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEfa11 family transposase"
                     /protein_id="HFQ0205243.1"
                     /translation="MNDSIKKMLRITEKDLMITEVSYETLQKKKTLVVDAVLSPTPRA
                     CRSCGSTVVDGNGKAIIVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCRTHWTAQ
                     SYFVQPRHSIANHVRYKIASLLTEKVSLSFIAKSCQVSLTTVIRTLKEFKSYLPKQSK
                     KILPRVLMVDEFRSHASIEDKMSFICADGETGKLIDVLPTRKLPRLTSYFLGCTNPEE
                     VEFLVTDMNAAYFQLTKRVLPNAKVVIDRFHIVKHMNQAFNELRIREMNELRKAGQKS
                     QAEKLKKNWRFLLKNRANINHYEYKTWKSFRAPKYPFLTEAMMIDRLLEFSPPLKEAY
                     PFFHELVEAFRDKDPDLFFSLLAELPETLDDSFREKLQNLLTYEEGITNAMIYPYSNG
                     KIEAKNTHIKTMKRVSYGF"
BASE COUNT          446 a          257 c          251 g          362 t
ORIGIN      
        1 attttaggta ttaaaaaaca tatcgttctc tagtatgatt aaatcaccac aaaataaaca
       61 actgagagga cgatacgcta tatgaatgat tctatcaaaa aaatgctgag aataacagag
      121 aaagatttga tgattacaga ggtctcttac gagacccttc agaagaaaaa gacgttggtc
      181 gtcgatgctg ttctctcgcc tactcctcgt gcttgtagaa gttgtggttc tactgtggta
      241 gatggaaacg ggaaagcaat tatagtgaaa aatggaaaaa aggaaacgat tgtccgtttt
      301 gaacaataca atcatatgcc tttggttatg cgcctaaaaa agcaacgcta tacctgtaaa
      361 aactgtcgca cccattggac ggctcaaagt tattttgtcc aacccagaca ttcaatcgca
      421 aatcatgtta gatataaaat tgcttcttta ctgactgaaa aagtatcttt atcttttatt
      481 gcgaaaagct gtcaggtatc tttgaccacc gttattcgta cattgaaaga gtttaaaagc
      541 tatttaccaa agcaatctaa gaagatcctc cccagagtat tgatggttga cgaatttcgt
      601 tcgcatgctt ccatagaaga taagatgagc tttatttgcg cggatggcga aacaggaaaa
      661 ttaatagatg ttttgcctac gcgtaaatta cctcgattaa caagctattt cttaggttgt
      721 accaatccag aagaagtaga attcttggtg acagacatga acgccgccta cttccagctc
      781 accaaacgtg ttctgccaaa tgcgaaagtc gtgattgatc ggtttcatat tgtcaaacac
      841 atgaatcaag cgttcaatga gttgcgtatc cgtgaaatga atgaacttcg taaagccgga
      901 cagaaaagcc aggcagaaaa actgaaaaag aactggcgct ttttgctaaa aaatcgtgca
      961 aacatcaacc attatgaata caaaacatgg aaaagtttcc gagcaccaaa atacccattt
     1021 cttactgaag caatgatgat tgatcgattg cttgagtttt ctccgcccct aaaggaggcg
     1081 tatccctttt ttcatgaatt agttgaagcc tttcgagaca aagaccctga cttatttttc
     1141 tccttattgg cagaacttcc cgaaacgtta gatgacagct ttcgggaaaa gcttcaaaac
     1201 cttctgacct atgaagaagg catcaccaac gcaatgatct atccttattc caatggaaaa
     1261 atagaagcga agaataccca cataaagaca atgaaacgag tatcctacgg atttaa
//
LOCUS       DAZKKZ010000186         1247 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.196, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000186 DAZKKZ010000000
VERSION     DAZKKZ010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1247)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1247)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1247
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.196"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            200..742
                     /locus_tag="ACG8LA_003037"
     CDS             200..742
                     /locus_tag="ACG8LA_003037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0205244.1"
                     /translation="MLLKVAIKCYCVKNKGGIIYEKIVPRGACLLLALCLSLSAVGCQ
                     KSNENNKIKEGQSISSEEEGMSINANGKNETFKPSDYTLEAKKEYVYEYLGLKFKLSD
                     KFRNYIADKKIAMLDDQSPIDKELKYAILTFEKMTEEQKNAVIEKMGDGYKNWQNELE
                     RIGTIGIFEKNTSEEKNLKL"
     gene            898..>1247
                     /locus_tag="ACG8LA_003038"
     CDS             898..>1247
                     /locus_tag="ACG8LA_003038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA disulfide reductase family protein"
                     /protein_id="HFQ0205245.1"
                     /translation="MLSEKTDLENTEAFNKESVKDLRKLPTKDINGKDFTSKDFEKYD
                     LTMVNVFATWCTACVKEIPDLVEVQNEMKSKGVNIVGVVTDPVDDNGENKEAIEKSKL
                     IHEKTKASYPFLMP"
BASE COUNT          515 a          141 c          238 g          353 t
ORIGIN      
        1 attgatgaag cagatcccaa agggctgctt catcaatttt ttcgtaagtg tccgtacact
       61 tactgtgctt gctcatatat taatcgatca tatactaatc gtgtaagaac aactttaagc
      121 ataatactta tattgttata ccatagtttg gaaaaataaa aaattatatt tcatcaacgt
      181 ttcataaaag gtgtgtagaa tgttattgaa agtagctata aaatgctatt gtgtaaaaaa
      241 taaaggagga ataatttatg aaaaaatagt accaagagga gcatgcctat tacttgcatt
      301 atgtttgagc ttaagcgcag ttgggtgtca aaaaagtaat gaaaacaata aaataaaaga
      361 aggacaatcc ataagttctg aagaggaagg catgtcaatt aatgcaaatg gcaaaaatga
      421 aacttttaag ccatcagatt atacattgga ggcaaagaaa gaatatgttt atgaatattt
      481 agggcttaaa tttaaactct cagacaaatt tagaaattat atagctgata aaaagatagc
      541 gatgttagat gatcaaagtc ctatagataa agaactaaag tatgctattt tgacatttga
      601 gaaaatgaca gaagaacaaa agaatgcagt tatagaaaag atgggcgatg gatataaaaa
      661 ttggcaaaat gagcttgaaa gaattgggac tattggtata tttgaaaaaa atacatcaga
      721 agaaaaaaat ctaaaattat aaaatgtgat actcatacta aaataggagt ttcaagtgat
      781 ggaaaatacg attgctattt aagcacaaat agcggagctg aaagtaatct tctggatgaa
      841 ttaaaaagaa ctgagattca aattatagat aaaaaagaac gtcctaaaaa tggttttgtg
      901 ctatcagaaa aaactgattt agaaaataca gaagcattta acaaagaatc ggttaaagat
      961 ttacgtaaac taccaacaaa ggacataaat ggcaaggatt ttacaagtaa agattttgag
     1021 aagtatgatc ttactatggt aaatgtattt gcaacttggt gtacagcttg tgtaaaggaa
     1081 attcctgatt tggttgaggt tcagaatgaa atgaaaagca agggtgtaaa tatcgttgga
     1141 gttgttacag atcctgttga tgataacggt gaaaacaagg aagcaattga aaagtcaaag
     1201 ttaatacatg aaaagacaaa ggcttcatat cctttcttaa tgccaga
//
LOCUS       DAZKKZ010000187         1237 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.197, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000187 DAZKKZ010000000
VERSION     DAZKKZ010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1237)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1237)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1237
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.197"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            94..>1237
                     /locus_tag="ACG8LA_003039"
     CDS             94..>1237
                     /locus_tag="ACG8LA_003039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086557923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HFQ0205246.1"
                     /translation="MSHTQLIKDTLNILDLNIYFEENCLTKEKYKGQICLIYKGTLLY
                     KPEECSHCLCVVPSRIIRWGTTTVRLLLNDVSEYRTYLELKKQRFKCKSCQRTFVADT
                     SVAEKHCFISQKVRWSVIARLKENTSMTEIARQKNISTSSVYRVMKRFYRPLNPFKQT
                     LPKVLCFDEFKSVRSVASAMSFIMMDGQSHALLDIVENRRLPYLERYFSRFSLATREA
                     VQLIVIDMYAPYVSLVKKLFPNAQLIIDRFHIVQHIGRTFLNHRVKETTVRLKGNSHS
                     QRGLGKKLKRYWKLLQKEEAKLNYEKRVWRASFKDYLTESEIADRLLAACPNLRQGYQ
                     LYQDILYAVKKRDQSLFEDCLTRDISGLPETYTTTLRTFKKFLPQIQ"
BASE COUNT          385 a          241 c          240 g          371 t
ORIGIN      
        1 tcaccaacat cttttttgta taaaaaaata tagaaaagac accctgaaat cctttagaat
       61 taatttggct accaattcat aggaggattc aagatgtctc atactcagct tatcaaagat
      121 accctaaata ttctagacct aaatatctat ttcgaggaaa attgtttaac taaagaaaaa
      181 tacaaagggc aaatttgctt gatttacaaa ggaactcttc tgtacaagcc agaagagtgt
      241 tcccattgtc tttgtgtcgt cccctctagg atcattcgtt gggggacgac aaccgttcgg
      301 ttgttactga atgatgtgtc tgagtatcgc acttatctgg agctgaagaa acaacgattt
      361 aaatgtaagt cttgccaaag aacattcgta gcggatacct ctgttgctga aaaacactgt
      421 ttcattagtc aaaaagttcg ttggtctgtc attgctcgct taaaagagaa tacttccatg
      481 acggaaatcg ctcgtcagaa aaatatttcc acttcttcgg tctatcgtgt catgaagcga
      541 ttctaccgcc cattgaatcc tttcaaacag actttgccaa aggtcttatg ctttgatgaa
      601 ttcaaatcgg ttcgaagtgt tgccagtgca atgagtttta tcatgatgga cggacaaagc
      661 catgcattat tggatattgt cgaaaatcga cgcttgcctt atttagaacg ctatttttct
      721 cggttttcat tagcgactcg tgaagccgtt caattgattg ttattgatat gtatgcgcct
      781 tatgtttcgt tggtgaaaaa gcttttcccg aatgctcagt tgatcatcga tcgtttccac
      841 atcgtccaac atattggcag aactttcttg aatcatcgag tgaaagaaac cacggtacga
      901 cttaaaggaa attcccactc tcaacgaggg ttagggaaaa aattgaagcg ctattggaaa
      961 ctcctacaaa aagaagaagc aaagttaaac tatgaaaaac gggtttggcg tgccagtttt
     1021 aaagattatt tgactgaaag tgagattgcc gatcgactgt tagctgcttg tcccaactta
     1081 cgccaaggct atcagttata ccaagacatt ctttatgcgg taaagaaaag agatcagtca
     1141 ctatttgagg attgtttaac tagagacatt agcggtctgc cagaaaccta tacaaccact
     1201 ttacgaacgt ttaaaaagtt tctgccacag atccaaa
//
LOCUS       DAZKKZ010000188         1207 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.198, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000188 DAZKKZ010000000
VERSION     DAZKKZ010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1207)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1207)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1207
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.198"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            110..1195
                     /gene="xerS"
                     /locus_tag="ACG8LA_003040"
     CDS             110..1195
                     /gene="xerS"
                     /locus_tag="ACG8LA_003040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HFQ0205247.1"
                     /translation="MKNTEIYQKIDTIILHMPDYIKDFVQDREDKDQSPRTTLEYLKN
                     YKLFYEWLLSESIVPDTSITSIRQLTAYDLNLYKSHLKRRTKENVKKETTKTKLKDNN
                     NLGLSTSTINRNITALKVLFKYLSKSSNNPLGKPYLENNPMDQVATITDKTTLAARAN
                     AIEKKLFLDEDTQNYLDYIANEYKKTLSKRALIYYQRDVERDLAINALILGSGLRLSE
                     VVNINLEDLSLEKNNVVVTRKGNKRDAVNIAAFAMEYLANYLAIRKERYKVTENEKAL
                     FLAIYQGEAKRISGIAIERMVAKYSKGFRVQVSPHKLRHTLATRLYQQTNSLVLTAQQ
                     LGHTSTNTTTLYTHIDNAATIDALNAL"
BASE COUNT          487 a          202 c          184 g          334 t
ORIGIN      
        1 aaataaatta ataaatttca gagtatacca attgacaaaa cactctataa ttggtatagt
       61 ccaattatag agatactcct ctcccctact tatcgaaagg atgaataaca tgaaaaatac
      121 agaaatatat caaaaaatag atacaatcat acttcatatg cccgattata taaaagattt
      181 tgttcaagat cgtgaggata aagatcaatc acctcgaact actttagaat atctaaaaaa
      241 ttataagctc ttttatgaat ggcttctgag tgagtctatc gttcccgata cttcaatcac
      301 ctcgataaga cagttaactg cctatgatct aaacttgtac aaatctcatt tgaaacgtcg
      361 cacaaaggaa aatgtaaaaa aagagacaac aaaaactaag ctcaaagata ataataactt
      421 aggtctatct acttctacta tcaatagaaa tatcacagca ttaaaggttc tatttaaata
      481 tctttcgaaa agttccaata atcctttagg aaaaccatac ttagaaaata atcctatgga
      541 tcaagtagca actatcacag ataaaactac gttagctgcc cgtgcaaacg caatcgagaa
      601 aaaattattt ctagacgaag atacacaaaa ttatctagat tatattgcca atgaatataa
      661 aaaaactttg agcaaacgag ctttgatcta ttatcaacga gatgtagaaa gagacctggc
      721 gatcaatgca ttgattttag gatctggatt aagactctcc gaggttgtaa atattaattt
      781 agaggaccta tctttagaaa agaataatgt ggtagtaact agaaaaggaa ataagagaga
      841 cgcagtaaat atagcagcat ttgcaatgga atatttagct aattatctag ctattcggaa
      901 agaacgatac aaagtaacag aaaacgaaaa agctttattt ctagcaattt atcaaggaga
      961 agccaagcgt atatccggta ttgcaatcga acggatggta gcaaaatatt caaaaggatt
     1021 cagagtccaa gtcagtccac ataaattacg tcatactttg gctactagac tctatcaaca
     1081 gacaaattca ttggtattaa ctgcccaaca attgggacat acaagtacaa atacaacaac
     1141 tttatatact catatagaca atgcagctac aattgatgct ttgaacgctt tgtaaatgta
     1201 gtaaaaa
//
LOCUS       DAZKKZ010000189         1195 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.199, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000189 DAZKKZ010000000
VERSION     DAZKKZ010000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1195)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1195)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1195
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.199"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..590
                     /locus_tag="ACG8LA_003041"
     CDS             <1..590
                     /locus_tag="ACG8LA_003041"
                     /inference="COORDINATES: protein motif:HMM:NF015839.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF334 domain-containing protein"
                     /protein_id="HFQ0205248.1"
                     /translation="SEQDRNERTNILMKRLEASTSNFNNKLDVFEEKTKHARLNFETT
                     AKHYIKRLDEDNLKLDFQQAIQDELSDTKDEIREVTKQAREETKEYKEILESKIKDHN
                     KVVDKSNTALKVMTKGVTNIFFVLIIFVLVMLVTGPIGHFFGIEHLYSFINGFIDDHE
                     SAWRYLMLILYAVPYVFFAIILWLIALFFRVFNDL"
     gene            1058..>1195
                     /locus_tag="ACG8LA_003042"
     CDS             1058..>1195
                     /locus_tag="ACG8LA_003042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HFQ0205249.1"
                     /translation="MNHFKGKQFKKDVIIVAVGYYLRYNLSYREVQELLYDRGINVCH
                     TT"
BASE COUNT          452 a          164 c          230 g          349 t
ORIGIN      
        1 agagcgagca agacaggaac gagagaacaa acatactcat gaaaagacta gaggcttcga
       61 cctcgaactt taataataag ttagatgttt ttgaagaaaa gactaagcat gcaagattaa
      121 actttgaaac aactgcaaag cactatatta aacgacttga tgaagataat ttgaaattag
      181 attttcaaca agctattcaa gatgaattaa gcgatactaa agacgaaata cgtgaagtga
      241 cgaaacaagc gagagaagaa acaaaagagt ataaagaaat cttagaaagt aaaataaaag
      301 accataacaa agtggttgat aaatcgaata cagcgctaaa agtgatgaca aaaggcgtta
      361 caaatatatt ttttgtgcta attatttttg tacttgtaat gcttgtgaca ggtccgatag
      421 gtcatttctt tggtattgaa catttatata gctttattaa tggttttatt gatgaccacg
      481 aaagtgcatg gcgatatttg atgttgatac tttatgcagt accctatgta ttcttcgcta
      541 tcattctgtg gctcatagca ttgtttttta gagtatttaa tgacctttag gtagatttat
      601 atataaaaag ggctaaatac gcaaaatacc cccttaaaat gcaaaataaa tgcaaataag
      661 ggggtaactc cttatgaaaa aacaactaat agtattataa cacgttttta tgccgagaaa
      721 acttattggt tggaatgggc tatgtgttag ctaacttgtt agcgagttgg ttggacttga
      781 attgggatta atcccaagaa agtaccaact caacaacaca taaagccctg taggttccga
      841 ccaataagga aattggaata aagcaacgaa aggagttgag taaaatgagt gagaaaacga
      901 agaaaatcat tcgagtatca ttagcttttt cacaagtagt agtgcaatca ttgatagttt
      961 attatactta ccagcaatat aaatggttct gttgcaaagt tttccaaaaa atctatttta
     1021 gtgtaaaatt gagaaaaaag acagagagga cagagtaatg aatcatttta aaggcaaaca
     1081 attcaaaaaa gacgtcatta ttgtcgctgt tggttactac ctgcgttaca atctaagcta
     1141 tcgtgaagtt caggaattgt tatatgatcg tggaataaat gtttgtcata ctacg
//
LOCUS       DAZKKZ010000190         1180 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.200, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000190 DAZKKZ010000000
VERSION     DAZKKZ010000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1180)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1180)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1180
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.200"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..506
                     /locus_tag="ACG8LA_003043"
     CDS             <1..506
                     /locus_tag="ACG8LA_003043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF2479 domain-containing protein"
                     /protein_id="HFQ0205250.1"
                     /translation="DGLMADIVQLKEDGVAKYLKTHVEAIDGKEALVQTDGDQAIAGH
                     KNFSGSVTINNKRVLTTDDNRYEVVNLVVTNGNTGTAKLYREGKTVSIYFVALNGKSS
                     GGNDSVILTVPEGYRTPISFEQLVGSIDRSTLNSAQLSIGADGAIKWRRNSSYGSAYS
                     FVITYSI"
     gene            520..951
                     /locus_tag="ACG8LA_003044"
     CDS             520..951
                     /locus_tag="ACG8LA_003044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0205251.1"
                     /translation="MKVVYKSIKPYGFEQIILNNQENIPENCTEIKPPVPNWRPRFDF
                     DKKQWVELATEEEKKGNAVDSVDELANIKALYETLKAENDELKQLNSKAMLNNVAIKQ
                     ENVLLKEKSESLAQLNSKTMLASVQNTKEIEEIKKQLQGGK"
     gene            953..1090
                     /locus_tag="ACG8LA_003045"
     CDS             953..1090
                     /locus_tag="ACG8LA_003045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HFQ0205252.1"
                     /translation="MYSYEDIKLMYDWGCFTNEQVMVFVPLCITEEEADKIISKEESA
                     S"
BASE COUNT          432 a          167 c          260 g          321 t
ORIGIN      
        1 gggacggttt aatggctgat attgtgcaat taaaagaaga cggagttgct aaatacttaa
       61 aaacgcatgt agaagctatt gatggtaaag aagcattggt gcagacagat ggagaccaag
      121 ccattgcagg acataagaat ttttcaggtt ctgtaacaat caataataaa cgtgttttga
      181 cgactgatga taacagatat gaagtggtaa atctggttgt cactaacggt aatacaggga
      241 cagcaaagct ttatcgtgaa ggaaaaacag tttctatata ttttgtggct ttaaacggaa
      301 aaagtagtgg cgggaatgat tcggttattt taactgttcc agaaggctat cggacaccaa
      361 ttagttttga acaactggtt gggtcaatag accgttctac tttgaacagt gctcaactat
      421 ctattggcgc agacggagcc attaaatgga gaagaaattc aagttatgga tcagcttatt
      481 catttgttat cacttattca atttaaggga ggaaatctaa tgaaagtagt ttacaaatca
      541 atcaagcctt acggattcga gcaaatcatt ttgaacaatc aagaaaatat ccctgaaaac
      601 tgtacagaga ttaaaccacc agttcctaac tggagaccaa gatttgattt tgataaaaaa
      661 cagtgggttg agttagctac tgaagaagag aaaaaaggga atgctgttga tagcgtagat
      721 gaattggcta atattaaggc attatacgaa acgctgaagg cagaaaatga tgaattgaaa
      781 cagctaaatt ctaaagcaat gctaaacaat gtagcaatca agcaagaaaa tgtcttattg
      841 aaagaaaagt cagaaagttt agcgcagttg aattcaaaaa cgatgcttgc ttctgtacaa
      901 aataccaagg aaatcgaaga aatcaaaaaa caattacaag gtgggaagta acatgtattc
      961 atatgaagat atcaaactaa tgtatgactg gggctgtttc actaacgaac aagtaatggt
     1021 tttcgttccg ttgtgcatta ctgaagaaga agcagataaa atcattagca aagaagagag
     1081 cgcatcttaa ttgatgtgct ttttattttg attcaaggag ttgtcacatg attaatttag
     1141 gggaatgggg agcgatagca ggatcaataa ccgctatcgt
//
LOCUS       DAZKKZ010000191         1178 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.201, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000191 DAZKKZ010000000
VERSION     DAZKKZ010000191.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1178)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1178)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1178
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.201"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..660
                     /locus_tag="ACG8LA_003046"
     CDS             <1..660
                     /locus_tag="ACG8LA_003046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-guided endonuclease TnpB family protein"
                     /protein_id="HFQ0205253.1"
                     /translation="YISLLCKEEVRELPKSNSAVGIDLGIIDFAILSTGQKFDNNKFT
                     SKMEKKLKREQRKLSRRALLAKQKGINLFEARNYQTQKRKVARLHEKVMNQRTDFLNK
                     LSTEIIKNHDIICIEDLNTKGMLRNHKLAKSISDVSWSSFVSKLQYKADWYGRKIIKV
                     DKWFPSSQICSNCGHKDGKKSLEIREWTCPICHTHHDRDINASINILTEGLRLHSMGL
                     A"
     gene            736..1178
                     /locus_tag="ACG8LA_003047"
                     /pseudo
     CDS             736..1178
                     /locus_tag="ACG8LA_003047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558187.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          445 a          198 c          221 g          314 t
ORIGIN      
        1 tatatttctt tgttatgcaa agaagaagtt cgcgaactac ctaaatctaa ttctgctgtt
       61 ggtattgacc taggtattat agactttgca attctttcta ccggtcaaaa atttgataat
      121 aataaattta cgtccaaaat ggaaaagaaa ctcaaacgtg aacaacgtaa gttgtcaaga
      181 cgtgccttat tagctaaaca aaaaggtatc aatctgtttg aagctagaaa ttatcaaaca
      241 caaaaacgta aagtagcacg attgcatgaa aaagtaatga atcaacgtac tgattttctg
      301 aataagttga gtacagaaat tatcaaaaat cacgatatca tctgtattga agacttaaac
      361 acaaaaggca tgttgcgtaa tcataaacta gcaaaaagta tttcggatgt ttcttggtct
      421 agttttgtgt ctaaattaca atacaaggct gactggtacg gtcggaaaat catcaaagta
      481 gataagtggt ttccatctag ccaaatctgt tcgaattgtg gacataaaga cggcaagaaa
      541 tctctcgaaa ttcgagaatg gacttgccct atttgtcata ctcatcatga ccgagatatc
      601 aacgctagta tcaatatcct gaccgaaggt ctaaggctac actctatggg attggcttag
      661 tggataggct acaattaact agacagaaaa attaaggtgt gtagactaga agaaaacata
      721 ccaggaggaa tttttatgtc taagagaaca cgaagaactt tttcacaaga attcaagcaa
      781 caaatcgtca atctttactt agctggaaag ccacgtgtag aaatcattcg agaatatgaa
      841 ctaacggctt cagcatttga caaatgggta aagcaatcta aaacgagtgg ttcattcaaa
      901 gaaaaagata atcttacgcc tgaacaaaaa gaattgttag aactacgtaa aagaaaccag
      961 caattagaaa tggaaaatga tattttaaag caagcagcgc tgatattcgg acgaagagac
     1021 aagtaatcga tgcgaataag catctttacc ctatatcagc gatgtgcaga atattaggtc
     1081 tatcacgtca gtcctattat tatcaatcaa aaccaaagaa agacgaatca gaacttgaag
     1141 aagtagtcgc tgaagaattt atccgcagcc gaaaggcc
//
LOCUS       DAZKKZ010000192         1106 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.203, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000192 DAZKKZ010000000
VERSION     DAZKKZ010000192.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1106)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1106)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1106
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.203"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..1087
                     /locus_tag="ACG8LA_003048"
     CDS             <1..1087
                     /locus_tag="ACG8LA_003048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFQ0205254.1"
                     /translation="DINDDGSRKKVEKVGGDTRPEAEAALRKVLSDIDETGQYFLGTD
                     TRVKQYLDFWMEEYVKLNLKYNTYENYRFTIKNHINGYLGKKKLTDLSPALLQNFINA
                     EFKKGYSKKTMTITHSVLKNALNMAVYPWGLIKQNPMLYVKIPKYEARPTTKKDLKII
                     SLEDFDHMLEITPEGHPFYIPLNIGFYTGMRVGEVCGLTWDDVDFSNGTITVEKQMVK
                     NDGAWVYGTPKTSSSNRTIFIGQTLLAILKKHKKQQLENRMKYGKLYIDSNAVCTKED
                     GELVTPSVVKWNTRRISNALSLSFNFHSLRHTHATLLLENGAKMKEISERLGHSRISI
                     TMDTYSHVTDKMRNETVDIMENLRKNS"
BASE COUNT          403 a          192 c          214 g          297 t
ORIGIN      
        1 agatatcaat gatgatggct caagaaaaaa agtggagaaa gttggcggag acacccgacc
       61 agaggccgaa gctgctttac gaaaagtttt atcagatatt gacgaaacag gacaatactt
      121 tttaggtacg gatactcgag taaaacaata ccttgatttt tggatggagg aatacgttaa
      181 actaaatcta aaatacaata cctatgaaaa ctaccgattt accatcaaaa atcatataaa
      241 cggttattta ggaaagaaaa aacttacgga tctctcccct gctcttttac aaaatttcat
      301 caatgctgaa tttaaaaagg gttactcgaa gaaaacaatg actattactc actctgtcct
      361 taagaatgcg ctgaatatgg cggtttatcc ttggggatta atcaagcaaa atcctatgct
      421 gtatgtaaaa ataccaaaat atgaagcacg accaacgact aaaaaagatc taaaaatcat
      481 ttctcttgag gactttgatc atatgctaga aattactcct gaaggacatc ctttctatat
      541 tcctttgaat attggatttt atacgggaat gcgcgttggc gaagtttgtg gtctgacgtg
      601 ggatgatgtc gatttttcaa atggaacaat tactgtagag aaacaaatgg taaagaatga
      661 cggcgcatgg gtatatggta cgccaaagac aagcagttcc aatcgaacga tttttattgg
      721 acaaaccttg ctagcaattc tgaaaaaaca taagaaacaa caattagaaa atcgaatgaa
      781 gtatggaaag ctctacattg attcaaatgc agtatgtacg aaggaagacg gtgagctagt
      841 tacgccaagt gtagtgaaat ggaatactag gaggatatcg aatgcactct ccctctcttt
      901 taacttccat tctctcagac atactcatgc tacacttctt ctcgaaaatg gcgcaaaaat
      961 gaaagaaatc tctgaacgat tgggccacag cagaatttca attacgatgg atacttactc
     1021 gcatgtaaca gataagatga gaaatgaaac ggtcgatatc atggaaaatc ttagaaagaa
     1081 ttcttgattt ttgccaccga aaaaaa
//
LOCUS       DAZKKZ010000193         1067 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.204, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000193 DAZKKZ010000000
VERSION     DAZKKZ010000193.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1067)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1067)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1067
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.204"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(170..907)
                     /gene="erm(B)"
                     /locus_tag="ACG8LA_003049"
     CDS             complement(170..907)
                     /gene="erm(B)"
                     /locus_tag="ACG8LA_003049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011100845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HFQ0205255.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGNIP
                     YHLSTQIIKKVVFESRASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTITYEQVLSIFNSYLLFNGRK"
BASE COUNT          311 a          171 c          187 g          398 t
ORIGIN      
        1 gggtcccgag cgcttagtgg gaatttgtac cccttatcga tacaaattcc ccgtaggcgc
       61 tagggacctc tttagcttct tggaagctgt cagtagtata tctaataatt tatctccatt
      121 ccctttagta acgtgtaact ttccaaattt aaaaaagcga ctcatagaat tatttcctcc
      181 cgttaaataa tagataacta ttaaaaatag acaatacttg ctcataagta atggtactta
      241 aattgtttac tttggcgtgt ttcattgctt gatgaaactg atttttagta aacagttgac
      301 gatattctcg attgacccat tttgaaacaa agtacgtata tagcttccaa tatttatctg
      361 gaacatctgt ggtatggcgg gtaagtttta ttaagacact gtttactttt ggtttaggat
      421 gaaagcattc cgctggcagc ttaagcaatt gctgaatcga gacttgagtg tgcaagagca
      481 accctagtgt tcggtgaata tccaaggtac gcttgtagaa tccttcttca acaatcagat
      541 agatgtcaga cgcacggctt tcaaaaacca cttttttaat aatttgtgtg cttaaatggt
      601 aaggaatatt cccaacaatt ttatacctct gtttgttagg gaattgaaac tgtagaatat
      661 cttggtgaat taaagtgaca cgagtattca gttttaattt ttctgacgat aagttgaata
      721 gatgactgtc taattcaata gacgttacct gtttacttat tttagccagt ttcgtcgtta
      781 aatgcccttt acctgttcca atttcgtaaa cggtatcggt ttcttttaaa ttcaattgtt
      841 ttattatttg gttgagtact ttttcactcg ttaaaaagtt ttgagaatat tttatatttt
      901 tgttcatgta atctctcctg aagtgattac atctataaac aaatacagaa gttaaacgat
      961 ttgtttgtaa ttttagttat ctgtttaaaa agtcataaga ttagtcactg gtaggaatta
     1021 atctaacgta tttatttatc tgcgtaatca ctgtttttag tctgttt
//
LOCUS       DAZKKZ010000194         1064 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.205, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000194 DAZKKZ010000000
VERSION     DAZKKZ010000194.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1064)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1064)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1064
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.205"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            78..193
                     /gene="rrf"
                     /locus_tag="ACG8LA_003050"
     rRNA            78..193
                     /gene="rrf"
                     /locus_tag="ACG8LA_003050"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            203..276
                     /locus_tag="ACG8LA_003051"
     tRNA            203..276
                     /locus_tag="ACG8LA_003051"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:237..239,aa:Asn,seq:gtt)
     gene            316..405
                     /locus_tag="ACG8LA_003052"
     tRNA            316..405
                     /locus_tag="ACG8LA_003052"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:350..352,aa:Ser,seq:gga)
     gene            420..491
                     /locus_tag="ACG8LA_003053"
     tRNA            420..491
                     /locus_tag="ACG8LA_003053"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:453..455,aa:Glu,seq:ttc)
     gene            507..579
                     /locus_tag="ACG8LA_003054"
     tRNA            507..579
                     /locus_tag="ACG8LA_003054"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:540..542,aa:Val,seq:tac)
     gene            589..661
                     /locus_tag="ACG8LA_003055"
     tRNA            589..661
                     /locus_tag="ACG8LA_003055"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:622..624,aa:Asp,seq:gtc)
     gene            697..772
                     /locus_tag="ACG8LA_003056"
     tRNA            697..772
                     /locus_tag="ACG8LA_003056"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:730..732,aa:Phe,seq:gaa)
     gene            774..854
                     /locus_tag="ACG8LA_003057"
     tRNA            774..854
                     /locus_tag="ACG8LA_003057"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:808..810,aa:Tyr,seq:gta)
     gene            861..934
                     /locus_tag="ACG8LA_003058"
     tRNA            861..934
                     /locus_tag="ACG8LA_003058"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:893..895,aa:Trp,seq:cca)
     gene            937..1009
                     /locus_tag="ACG8LA_003059"
     tRNA            937..1009
                     /locus_tag="ACG8LA_003059"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:970..972,aa:His,seq:gtg)
BASE COUNT          252 a          239 c          286 g          287 t
ORIGIN      
        1 actcggaaaa aaacttatgt gacttcaaat ccagttttga gtgaacaaaa tttactcaat
       61 aaaagataac accacagtgt ggtggcgata gcgagaagga tacacctgta accatgccga
      121 acacagaagt taagcttctt agcgccgatt gtagtgaggg gttgcccctt gtgagagtag
      181 gacgtcgcca cgctgatgtt attccggcat agctcagttg gtagtagcgc atgactgtta
      241 atcatgatgt cgtaggttcg agtcctactg ccggagttct cattttgaga aagagtattg
      301 agcttctttc actctggaga gttgtccgag aggccgaagg agcatgattg gaaatcatgt
      361 agatggtgcc aaactgtctc aagggttcga atcccttact ctccgtagca aatttacctg
      421 gcccgttggt caagcggtta agacaccgcc ctttcacggc ggtaacacgg gttcgaatcc
      481 cgtacgggtc attttaattg aatgttggag gtttagctca gctgggagag catctgcctt
      541 acaagcagag ggtcagcggt tcgatcccgt taacctccat aatgaactgg ttccgtggtg
      601 taggggttaa catgcctgcc tgtcacgcag gagatcgcgg gttcgattcc cgtcggaacc
      661 gtcgttcttg ttattcaatt aataatttta aaatatggcg cggtagctca gttggtagag
      721 caacggattg aagctccgtg tgtcggcagt tcgattctgt cccgcgccac catggaggag
      781 tagcgaagtg gctaaacgcg acggactgta aatccgttcc ttagggttca gtggttcgaa
      841 tccactctcc tccattttat aggggcatag tttaaaggta gaacagcggt ctccaaaacc
      901 gttagtgtgg gttcaattcc tgctgcccct gccatggcga atgtggcgaa gtggttaacg
      961 caccggattg tggctccggc attcgtgggt tcgattccca tcattcgccc tttttattct
     1021 tggggtatag ccaagcggta aggcaaggga ctttgactcc ctca
//
LOCUS       DAZKKZ010000195         1058 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.206, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000195 DAZKKZ010000000
VERSION     DAZKKZ010000195.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1058)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1058)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1058
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.206"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(36..992)
                     /locus_tag="ACG8LA_003060"
     CDS             complement(36..992)
                     /locus_tag="ACG8LA_003060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0205256.1"
                     /translation="MELYTLPIIIKTEKMLKDLKQYYPLSAYEKKKLFHFLAINLLAE
                     QADSLDIASNQSLFFSDIGFYHLKGVLGEKSVIFINKTLSWLYLHDKLDQKYLRKNED
                     ETIEWLNERFIESFENQFNLLREETSQLIRRELTKIHFKLLHYTINKADEFPLDVSFF
                     RENYPAFYCYLIEYINDLTSKRKELLQDKFFLFFSYLLLLINHIPIQLISEPVKIIID
                     FSYGAAYNQFIKKNLSLYINLNTEVIEAGKPEFPDVIITNRNNLYEESASQVVVWLDP
                     PRAVDWGNLTKILLTIQEEKYKDSKIDKQIDDFPEEIIDRIE"
BASE COUNT          344 a          176 c          160 g          378 t
ORIGIN      
        1 tagaaaaagc agtcggactt tctaaaagaa gttcactatt cgatcctgtc gatgatttct
       61 tcaggaaaat cgtctatttg cttgtcaatt ttgctgtctt tgtatttctc ttcttggata
      121 gtcaacaaaa tctttgtaag attcccccag tctactgctc ttggcggatc gagccaaacc
      181 actacttgag atgcactttc ttcatataga ttattcctat tcgtgattat aacatccggg
      241 aactcaggct ttcctgcctc tatcacttcc gtgttcagat taatgtacaa gcttaaattt
      301 ttcttgataa attgattata ggcagcacca taagaaaaat cgatgatgat ctttactggt
      361 tcagaaatca gttgaatggg tatgtgattg atcaataata ataaataact gaaaaaaaga
      421 aaaaatttat cttgaagcaa ctctttgcgt tttgacgtta gatcatttat atactctatc
      481 aaatagcaat aaaatgctgg atagttttct ctaaaaaaag aaacatcaag tggaaattca
      541 tcagctttat taatagtgta atgcaaaagt ttaaaatgta ttttggttaa ctctcttcgg
      601 atcaattggc tcgtctcttc tcgcaacaga ttaaactgat tttcaaaact ttcaatgaat
      661 cgttcattca accattcgat tgtttcatct tcattttttc tcaagtattt ttgatccaat
      721 ttatcatgaa gataaagcca agagagtgtc ttattgataa aaataacgga tttttctcct
      781 aatactcctt ttaagtggta aaatcctata tccgaaaaaa atagcgactg attgctagca
      841 atatctaaag aatcagcttg ttcagccaac aggttgattg ctaaaaagtg gaataatttc
      901 tttttttcat aagcagacag aggataatac tgttttaaat cttttaacat tttttctgtt
      961 tttataatta taggtagcgt atacaattcc acaaaactta tctctgttga gttaaaaaga
     1021 ttatataaaa aaagccgaat gtttttagga ttccctgt
//
LOCUS       DAZKKZ010000196         1035 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.207, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000196 DAZKKZ010000000
VERSION     DAZKKZ010000196.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1035)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1035)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1035
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.207"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..>1035)
                     /locus_tag="ACG8LA_003061"
     rRNA            complement(<1..>1035)
                     /locus_tag="ACG8LA_003061"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          218 a          324 c          234 g          259 t
ORIGIN      
        1 agcacgtgtg tagcccaggt cataaggggc atgatgattt gacgtcatcc ccaccttcct
       61 ccggtttgtc accggcagtc ttgctagagt gcccaactga atgatggcaa ctaacaataa
      121 gggttgcgct cgttgcggga cttaacccaa catctcacga cacgagctga cgacaaccat
      181 gcaccacctg tcactttgcc cccgaagggg aagctctatc tctagagtgg tcaaaggatg
      241 tcaagacctg gtaaggttct tcgcgttgct tcgaattaaa ccacatgctc caccgcttgt
      301 gcgggccccc gtcaattcct ttgagtttca accttgcggt cgtactcccc aggcggagtg
      361 cttaatgcgt tagctgcagc actgaagggc ggaaaccctc caacacttag cactcatcgt
      421 ttacggcgtg gactaccagg gtatctaatc ctgtttgctc cccacgcttt cgagcctcag
      481 cgtcagttac agaccagaga gccgccttcg ccactggtgt tcctccatat atctacgcat
      541 ttcaccgcta cacatggaat tccactctcc tcttctgcac tcaagtctcc cagtttccaa
      601 tgaccctccc cggttgagcc gggggctttc acatcagact taagaaaccg cctgcgctcg
      661 ctttacgccc aataaatccg gacaacgctt gccacctacg tattaccgcg gctgctggca
      721 cgtagttagc cgtggctttc tggttagata ccgtcaaggg atgaacagtt actctcatcc
      781 ttgttcttct ctaacaacag agttttacga tccgaaaacc ttcttcactc acgcggcgtt
      841 gctcggtcag actttcgtcc attgccgaag attccctact gctgcctccc gtaggagttt
      901 gggccgtgtc tcagtcccaa tgtggccgat caccctctca ggtcggctat gcatcgtggc
      961 cttggtgagc cgttacctca ccaactagct aatgcaccgc gggtccatcc atcagcgaca
     1021 cccgaaagcg ccttt
//
LOCUS       DAZKKZ010000197         1005 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.208, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000197 DAZKKZ010000000
VERSION     DAZKKZ010000197.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1005)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1005)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1005
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.208"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(47..895)
                     /locus_tag="ACG8LA_003062"
     CDS             complement(47..895)
                     /locus_tag="ACG8LA_003062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HFQ0205257.1"
                     /translation="MSVISRIESMMEDYSSAEKKLANYIIGNIEKVPTMTANELAEAS
                     GLSAPTVVRFSKKIGFQSLTDFKITISTELQTGIDEGFSDIEANESFYSIKNKLGNNA
                     QVAIKETVDILEEETIQKVVECLESAETVFLYGVGASSLVVEDILQKWSRVGKPIIFE
                     KDIHVLLPQLVSNEKKKVLWLVSNSGRSADVVALAELAKSMNIEIIALTQFGNNPLSK
                     IADVLVQTSRPKEITNRSAATNSLLAQFATIDIIFYFYMAKNEKLSEKVKKTREAIQE
                     YFMDSK"
BASE COUNT          288 a          207 c          163 g          347 t
ORIGIN      
        1 tacgttttgt tattctaaaa aacttatata aaaaatagta aggtttttat ttcgaatcca
       61 taaaatattc ttggattgct tctcgtgttt ttttcacttt ttcgctaagc ttttcgtttt
      121 tagccatata gaaataaaaa atgatatcga tcgtagcaaa ttgggccaaa agtgaattag
      181 ttgccgcact tcgattcgtg atttcttttg gtctagatgt ttgtacgagt acatcggcta
      241 tcttgctaag cgggttattt ccaaattgcg tcaacgcaat gatttcgata ttcatgcttt
      301 tcgccagctc ggctaatgcg actacatctg cacttctacc tgagtttgaa acaagccaaa
      361 gcactttctt tttctcattg ctgacaagtt gcgggagcaa gacgtggata tctttttcaa
      421 aaatgattgg cttaccgaca cgagaccatt tttgcagaat atcttctact actaaagaag
      481 aggcgccaac cccatataaa aaaacagtct ctgccgattc caaacactct acgacttttt
      541 ggatcgtttc ttcttctaga atatctactg tttcttttat cgctacttgt gcattgttac
      601 caagtttgtt tttgatagag taaaaggact catttgcttc tatatcacta aaaccttcat
      661 cgattccagt ctgtagttct gttgaaatcg tgattttgaa gtccgtcaga ctttgaaaac
      721 cgattttttt ggaaaaacgt acaactgtcg gcgcactcaa cccggaagct tctgctaatt
      781 cattagctgt cattgtaggg accttctcaa tattaccgat aatgtagttg gccaactttt
      841 tttctgctga agaataatct tccatcatac tttcaatacg actaattacg ctcataagtt
      901 cctccaccct tttaatgata gtctatgtaa gtataccata tcagaccctt attcacggtc
      961 gtatactgga taaaaaacaa aaaaacaatc cgcccaacag aatat
//
LOCUS       DAZKKZ010000198         1003 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.209, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000198 DAZKKZ010000000
VERSION     DAZKKZ010000198.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1003)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1003)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1003
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.209"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            18..>1003
                     /locus_tag="ACG8LA_003063"
     CDS             18..>1003
                     /locus_tag="ACG8LA_003063"
                     /inference="COORDINATES: protein motif:HMM:NF033550.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HFQ0205258.1"
                     /translation="MILLNRSGNKRTYLRLKKQRYLCRACKKYFTARTYLVTPFCFIS
                     KQIHYKILEELTERQSIKAIGKHCDVSVTTVQRTLSALSSDIRQNLEYLPRCLLFDEF
                     RSLSTWHGKFSFSCMDGETGKLFEILPSRRKKDLVAFFMRFSLKARLGVHYIVTDMNA
                     PYFSLVKECFPNAQVIVDRFHIVQHLNRFFDAVRKRVMKTLDQKDPIQAKQYRQLKSL
                     FKLLLKSEDRLDYNTLTKRRNFNWRLLTETEVVDRLLKISPELKTAYRYYQDLLTAYQ
                     EKDPDTFFQLLRAMPGEVPLELHHIKKAFFKYEKGIRLALLKKYSNARLENL"
BASE COUNT          301 a          209 c          191 g          302 t
ORIGIN      
        1 atggcaagaa gatctctatg attctcctga atcgtagcgg taataaacgg acctatcttc
       61 ggttgaagaa acagcgatac ctctgccgag catgtaaaaa atattttacc gctcggacgt
      121 atctcgttac cccattctgc tttatttcta agcagattca ttacaagatc ttagaagaat
      181 tgacagagcg tcaatctata aaagcaattg gtaaacattg cgatgtttct gtgacaactg
      241 ttcagcggac attgtccgcc ttgtcatcag atatccgtca gaatcttgag tatttacctc
      301 ggtgtctatt attcgatgag tttcgttctc tttctacatg gcacggtaaa ttttcttttt
      361 cttgtatgga cggtgagacc gggaaactgt ttgagatctt acctagccgc cgtaaaaaag
      421 atctcgttgc ttttttcatg cgtttttctc tcaaagcgag gttgggtgta cattacatcg
      481 taacggatat gaacgctcct tatttctcac tagttaaaga gtgttttcca aatgcacaag
      541 tgatcgtcga tcggtttcac attgttcaac atctgaaccg cttcttcgat gcggttcgaa
      601 aacgtgtgat gaaaacactt gatcaaaaag acccaataca agctaaacag tatcgccaat
      661 tgaaatcctt attcaaatta cttttaaaat cagaggatcg tttagattac aatacactaa
      721 cgaaaagacg caatttcaat tggagactat tgactgaaac agaagtagtt gaccgccttc
      781 taaagatttc tcctgaactt aaaacagctt atcgttacta ccaagacctg cttactgcgt
      841 atcaggaaaa agatccagat acttttttcc agctgcttcg agcaatgcct ggagaagttc
      901 cattggaact gcaccatatc aaaaaagcct ttttcaaata cgagaaaggg attcggctgg
      961 cattactgaa gaagtattcg aatgcacgac tggaaaatct cca
//
LOCUS       DAZKKZ010000199         1002 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.210, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000199 DAZKKZ010000000
VERSION     DAZKKZ010000199.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1002)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1002)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1002
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.210"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(82..636)
                     /locus_tag="ACG8LA_003064"
     CDS             complement(82..636)
                     /locus_tag="ACG8LA_003064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFQ0205259.1"
                     /translation="MSYNVQPLRTNEEIQDFQFWLRRTSNPERDSFLFLFGINNGLRM
                     SDIIGLKVGDIRGKSKPIIVEHKTGKRKPIFIDNLREEILLYTEGKEENDWLFPSRQQ
                     GRHITRDRVYQIYADVAEKLGRDDIGTHTLRKTFGYHYYKKTRDIATLMFIFNHSSQA
                     ITKRYIGITEDEIGASLRGFKLGG"
BASE COUNT          325 a          186 c          107 g          384 t
ORIGIN      
        1 acttccgaaa attcagttat cttcattaat ctcaccttct aagttttcat tatacacaaa
       61 aaatatatcc taatatctca attagcctcc caatttaaaa ccacgtaacg atgcccctat
      121 ttcatcttca gttataccaa tgtacctttt tgtaattgct tgcgagctat gattaaaaat
      181 aaacattaag gtagcaatgt ctctagtttt cttgtagtag tgatacccaa aagtttttct
      241 taatgtatgt gttcctatat catctcttcc taatttttct gctacatctg catatatctg
      301 atagacacga tcccttgtta tatgtcgacc ttgttgccga cttggaaata accaatcatt
      361 ttcttcttta ccttcagtat ataataaaat ctcttctctc aaattatcta taaaaatcgg
      421 ttttcgctta cctgttttat gttcaacaat aataggctta cttttacctc gtatgtctcc
      481 aacttttaat cctataatat ctgacatacg taacccatta ttgattccaa acaaaaataa
      541 aaaactatct ctttctggat tacttgttct tcttagccaa aactgaaaat cttgtatctc
      601 ttcatttgtc cttaacggtt gtacattata gctcactatt gtttcccttc ttaaaaatat
      661 tctgagttca tgattatata tatattttac cataatcatg aacttatata tatactctgt
      721 taaaagtgaa gaaaatcaag gggtttagtt tatgatttta tatcatttca gtaactcaga
      781 atattccgac ttttttgtac aaaaaaatta accttactta tatgaagatt ctaagctctt
      841 atttaaattt tagacgggca gttatccgta gaagttctta gaatagctaa tttacataat
      901 taaattatat gaaatttaag tttgaacaat atactaagaa ctccccttac tataaagtga
      961 aataaattag catatgaata accgtgctac caaacttttc at
//
LOCUS       DAZKKZ010000200          983 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.211, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000200 DAZKKZ010000000
VERSION     DAZKKZ010000200.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 983)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 983)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..983
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.211"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(34..107)
                     /locus_tag="ACG8LA_003065"
     tRNA            complement(34..107)
                     /locus_tag="ACG8LA_003065"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(71..73),aa:Ile,seq:cat)
     gene            complement(662..976)
                     /locus_tag="ACG8LA_003066"
     CDS             complement(662..976)
                     /locus_tag="ACG8LA_003066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0205260.1"
                     /translation="MDFYSNFILIIAILLLLNIWFFDKSRNAGIGFRTKRSTSSEKKW
                     VYSQTIFYGGVISISLLSSTLYSFNVIDVSMSNFISIIGILISAIITQLLLVFEEKSK
                     NN"
BASE COUNT          363 a          154 c          154 g          312 t
ORIGIN      
        1 tctaacacag aacgattcaa ttggctacat taatgtaccc tgtaggactc gaacctacga
       61 ccggacggtt atgagccgtc tgctctgacc aactgagcta agggtagtgg ttgttgccac
      121 ataaagccat aaacaatcaa ccagtagaat gcgtggcaac aaacctgtta tcgcatatct
      181 tggagtgtga ctatttatga gtgatagtga agatatgcgt ctccatatat gtatggttga
      241 gacagataaa catgtatgaa aaacgttgtt aaatcaacgt ttttttattt tggtcaagga
      301 gagaaaagta gagaaataca aaattttttg cattgatttt gcattcaaaa aaacattcaa
      361 acatttagaa atccccaata cgtattcagg aaaatctatt ttaaggttta caaaaagaac
      421 ttttgttcgt acactctttt tgaggtgaac ttttatgctg atggaaggaa aaacacaatt
      481 atggtttaag catgttcctt caaataagtt ttttaattat aaactctaga gaaattaatt
      541 catcctaaca taaaataatt gttcactcaa aagtttttct agaacaatta aaacagcagg
      601 cttcacattc gctatacatt tgtaagaagt aataattcct gtactaaaag gcataattgc
      661 tttaattatt ttttgacttc tcttcaaaca caagaagtag ttgtgtaata attgcagaaa
      721 taaggattcc aataatagat ataaaatttg acatggaaac gtctataaca ttaaaagaat
      781 aaagtgttga agaaagtaaa ctgattgaaa taacccctcc gtaaaaaata gtctgtgaat
      841 atacccactt tttttcagaa gacgtacttc gtttggttct aaaacctatc cctgcatttc
      901 tactcttatc aaaaaaccaa atatttagaa gtaataatat tgctattatt aagataaaat
      961 tactgtaaaa atccaaaagc tat
//
LOCUS       DAZKKZ010000201          960 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.212, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000201 DAZKKZ010000000
VERSION     DAZKKZ010000201.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 960)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 960)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..960
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.212"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            32..>960
                     /locus_tag="ACG8LA_003067"
     CDS             32..>960
                     /locus_tag="ACG8LA_003067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042834 - peptidoglycan binding [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan recognition family protein"
                     /protein_id="HFQ0205261.1"
                     /translation="MKKKITITAMSLLTALFLLPINTFAYTINDEYNLAPNQGDSRLA
                     IPNKIILHETGIDAPARNVAANMKNNYNGSNSYTTDVIGDGGIVYRVGEQGYVSWGAG
                     NANPYAPVQIELQRTYDKALFEKNYRAYIEYTRDSAKKYGIPLTLDQGTSLFTKGIIS
                     HLWVTNYVWGNHTDPYGYLSQMGVSKEKLAYDLAHGFTDENPTTSENKPVIDPTRAGA
                     ANPTLTDGTNHAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELARVRADG
                     IYRPDVNQAYNTSGNVGYHVSFNMRNFPSKKVYV"
BASE COUNT          327 a          162 c          197 g          274 t
ORIGIN      
        1 tctcggctga aagcgaagaa ggaggaaaca aatgaaaaag aaaattacta ttactgcgat
       61 gagcctgtta acggctcttt ttttattacc cattaatacg tttgcttata ctattaatga
      121 cgagtataat ttagcgccga atcaaggaga ctccagatta gcaattccta acaaaattat
      181 tttgcacgaa actggaatag atgcaccagc aagaaacgta gccgccaaca tgaaaaataa
      241 ttataacgga agcaattctt atactacaga tgttattggt gacggtggga ttgtttaccg
      301 tgtgggtgag caaggatatg tttcgtgggg agctggtaac gctaatcctt atgcgcctgt
      361 acagattgaa ttacagcgca catatgataa agcattgttt gaaaaaaact atcgagctta
      421 tattgaatat acaagagata gtgcaaaaaa atatggaatt ccattgactc ttgatcaagg
      481 aacttcttta tttacaaaag gaatcatttc tcatttgtgg gtgacaaatt atgtttgggg
      541 gaaccacaca gatccatatg gttacttatc gcaaatggga gttagcaaag aaaagcttgc
      601 ttatgattta gctcatggat ttaccgatga aaatccaaca acttctgaaa acaagcctgt
      661 cattgatcca acacgagctg gtgcagctaa tcctacgctg acagatggaa caaatcacgc
      721 ccacattgat cagtttgggg aaatcgaaaa cgcaaacttg catgtggctg gatggcacat
      781 tgctaactat aaatacgagt atattttcat tatggactac aatactggga aagaattagc
      841 tcgagtaaga gctgatggaa tttatagacc agatgtaaac caagcttata atacttctgg
      901 aaatgttggt tatcatgtat ctttcaatat gcgtaatttt cctagtaaga aagtctatgt
//
LOCUS       DAZKKZ010000202          943 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.213, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000202 DAZKKZ010000000
VERSION     DAZKKZ010000202.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 943)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 943)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..943
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.213"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..>943
                     /locus_tag="ACG8LA_003068"
     rRNA            <1..>943
                     /locus_tag="ACG8LA_003068"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          293 a          187 c          274 g          189 t
ORIGIN      
        1 attgtgtgaa tacatagcac attcgaggta gacgcagaga actgaaacat ctaagtacct
       61 gcaggaagag aaagaaaatt cgattccctg agtagcggcg agcgaaacgg gaaaagccca
      121 aaccagcaag cttgcttgtt ggggttgtag gactccaata tggtagttct ttcagatagt
      181 cgaatgactt ggaaaagtca gtcaaagagg gtaaaaaccc cgtagacgaa atgtggaaga
      241 cacctaggag gatcctgagt acggcggaac acgagaaatt ccgtcggaat ccgggaggac
      301 catctcccaa ggctaaatac tccctagtga ccgatagtga accagtaccg tgagggaaag
      361 gtgaaaagca ccccggaagg ggagtgaaat agaacctgaa accgtgtgcc tacaacaagt
      421 caaagcccgt taatgggtga tggcgtgcct tttgtagaat gaaccggcga gttacgattg
      481 catgcgaggt taagttgaag agacggagcc gcagcgaaag cgagtctgaa tagggcgttt
      541 gagtatgtag tcgtagaccc gaaaccatgt gatctaccca tgtccaggtt gaaggtgcgg
      601 taaaacgcac tggaggaccg aacccacgta cgttgaaaag tgcggggatg aggtgtgggt
      661 agcggagaaa ttccaaacga acttggagat agctggttct ctccgaaata gctttagggc
      721 tagcctcgga attgagaatg atggaggtag agcactgttt ggactagggg cccatctcgg
      781 gttaccgaat tcagataaac tccgaatgcc attcattcat atccgggagt cagactgtga
      841 gtgataagat ccatagtcga aagggaaaca gcccagacca ccagctaagg tcccaaaata
      901 tatgttaagt ggaaaaggat gtggggttgc acagacaact agg
//
LOCUS       DAZKKZ010000203          893 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.215, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000203 DAZKKZ010000000
VERSION     DAZKKZ010000203.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 893)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 893)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..893
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.215"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            252..875
                     /locus_tag="ACG8LA_003069"
     CDS             252..875
                     /locus_tag="ACG8LA_003069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFQ0205262.1"
                     /translation="MYLAYLRVSSDDQSLARQHKLIENWSVKNNIAEDDLKIFEEKVS
                     GKNIENRPELQELISFIRERDTIIIPSLDRLARNSKDTKDLLQLFRSKGASIEILDLP
                     SFNGVTDPALRDLLTNLVIEVFSYVAENERKKIKERQKQGIEIAKKNGRYTGKKIQYH
                     ANATGKNKLIYDEIVDGLKKKETISKIAKNAGVTRKTVYRVKRDLGM"
BASE COUNT          328 a          129 c          167 g          269 t
ORIGIN      
        1 aactaatgtc cttatttttg tgttcacatt tctgttacct aagaaatact taaaggaggt
       61 gatgtagcca gcaacgacta caacttgaac ccgctatcta cagtttattt gttgtttctt
      121 ttgggtatac tctaatggta caaatccata tttgcttaaa gcgttgattt ttcagcggtt
      181 tttctttatt gcaaagtgta ccctaagacc tgtatactaa tagtaaatag attggatagg
      241 aatgatggca aatgtattta gcttatttaa gagtttcttc cgacgatcaa agtttagctc
      301 ggcaacataa gctaattgaa aattggtcag tcaaaaataa tattgctgaa gacgatttaa
      361 aaattttcga ggaaaaagtc tctggaaaaa atattgaaaa cagaccagag ctgcaagagc
      421 ttatttcttt catacgtgaa cgagatacga ttattattcc tagtcttgat cgattagcaa
      481 gaaatagtaa agatacaaaa gacttacttc aattgtttcg tagtaaaggt gcttctattg
      541 aaatattaga cctaccgtcg tttaatgggg taactgaccc tgcattaaga gacttgctaa
      601 caaatttagt catagaagtg tttagctatg ttgctgaaaa cgaacggaaa aaaatcaaag
      661 agcgtcaaaa acaaggcatt gaaattgcaa agaaaaatgg tcgttatact ggtaaaaaga
      721 ttcaatacca tgccaatgca acaggaaaaa acaaattgat ttacgatgaa attgttgatg
      781 gtctgaagaa aaaagaaact atttctaaaa tagcaaagaa cgcaggagtt acaagaaaaa
      841 ccgtttatcg agtaaaaaga gatttaggaa tgtaatatgt tccagttaga aag
//
LOCUS       DAZKKZ010000204          865 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.216, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000204 DAZKKZ010000000
VERSION     DAZKKZ010000204.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 865)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 865)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..865
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.216"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            5..>865
                     /gene="bsh"
                     /locus_tag="ACG8LA_003070"
     CDS             5..>865
                     /gene="bsh"
                     /locus_tag="ACG8LA_003070"
                     /EC_number="3.5.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase"
                     /protein_id="HFQ0205263.1"
                     /translation="MCTSITYVTSDHYFGRNFDYEISYNEVVTVTPRNYKLNFRKVND
                     LDTHYAMIGIAAGIADYPLYYDATNEKGLSMAGLNFSGYADYKEIQEGKDNVSPFEFI
                     PWILGQCSTVGETKKLLKNINLANINYSDELPLSPLHWLLADKEKSIVIESMKDGLHI
                     YDNPVGVLTNNPSFDYQLFNLNNYRVLSSETPKNNFSNQISLNAYSRGMGGIGLPGDL
                     SSVSRFVKATFTKLNSVSGDSESESISQFFHILGSVEQQKGLCDVGDGKYEYTIYSSC
                     CNVDKGIYYYR"
BASE COUNT          291 a          116 c          158 g          300 t
ORIGIN      
        1 aactatgtgt acgtctatta cttatgtaac aagtgatcat tattttggaa ggaattttga
       61 ttatgaaata tcttacaatg aagtagttac tgttactcca agaaattata agttgaattt
      121 tcgaaaggta aatgatttgg atactcatta tgcaatgatt ggtattgccg ctggtatagc
      181 tgactaccct ctttattacg atgcgacaaa tgaaaaagga ttgagtatgg ctgggctaaa
      241 tttttctggg tatgctgatt ataaagaaat acaagaaggg aaagacaatg tatctccttt
      301 tgaatttatt ccttggattt taggacaatg ctcaacagta ggagaaacta aaaaattgtt
      361 aaaaaatatc aatttagcaa atataaatta tagtgatgaa cttcctttat cccctttaca
      421 ttggctatta gctgataaag aaaaatcaat tgtcattgaa agtatgaaag atggacttca
      481 tatatatgat aaccctgtgg gcgttcttac caataatcct tcatttgact atcaattatt
      541 taatttaaac aattatcgtg tcttatcgag tgaaactcct aaaaataatt tttcaaatca
      601 aataagtttg aatgcctata gccgcggtat gggagggata ggcttgcctg gagatttatc
      661 ctcagtatct cgttttgtta aagcgacttt tacgaagctg aattctgtat ctggagattc
      721 agagtcagaa agtattagtc aatttttcca tatcttaggt tcagtagaac aacaaaaagg
      781 tttgtgtgat gttggtgatg gaaaatatga atatacaatt tattcttctt gttgcaatgt
      841 tgacaaagga atctattatt atcga
//
LOCUS       DAZKKZ010000205          850 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.218, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000205 DAZKKZ010000000
VERSION     DAZKKZ010000205.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 850)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 850)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..850
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.218"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
BASE COUNT          321 a           98 c          110 g          321 t
ORIGIN      
        1 attagcaata tataaaagaa ggtatcaaga gtcacagtga atttattccg aaaagtgaaa
       61 agagcaaata taaaatttaa taaaaatata gaactaaata ggaaaacgta gacgtaattt
      121 tctacgtttt ccttttcata tatattaaat attacggaaa attatataaa ctaatttagt
      181 gttttgtttg taattcctaa ttttgctcca cttttagata atttttaggt ctatttaact
      241 catcagacat tctatgctca tttttctcca aatttgtttc aactctttcg tacttaattt
      301 tgcgtatttg aaaattcttc ttttagagta cttttattac gatactagta tgatatatat
      361 ctatagcaaa cagttaaaat cttcctaaaa taagcgaata gcattcctaa aacctataaa
      421 atttttagat gaagcgacaa gtggacaatt aataaactac ttgaacatga aattatggat
      481 cacctttcaa atttagaaaa tggaattctt atacttattg cgcaacattt attgattaca
      541 aaattatgtg acaaaaagaa ctagtagaag aaggaataat ggcttgataa taaagtacta
      601 cctattaaag gtagtacttt atttaattta gtataaatta acatactact atattttagg
      661 tttcatatta tataaattaa taataaaata ccatttgttg gtagtataat ttaaaggtaa
      721 taagttattc ttttattact atgtttgggt tttatagcaa ggaaagttta ataagagttt
      781 ggacctagca aacaatatta atgaggtcat taaatcttat tatctttggt tctgttgcaa
      841 agttttaaat
//
LOCUS       DAZKKZ010000206          839 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.219, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000206 DAZKKZ010000000
VERSION     DAZKKZ010000206.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 839)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 839)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..839
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.219"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            51..746
                     /gene="vanR-A"
                     /locus_tag="ACG8LA_003071"
     CDS             51..746
                     /gene="vanR-A"
                     /locus_tag="ACG8LA_003071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin resistance response regulator
                     transcription factor VanR-A"
                     /protein_id="HFQ0205264.1"
                     /translation="MSDKILIVDDEHEIADLVELYLKNENYTVFKYYTAKEALECIDK
                     SEIDLAILDIMLPGTSGLTICQKIRDKHTYPIIMLTGKDTEVDKITGLTIGADDYITK
                     PFRPLELIARVKAQLRRYKKFSGVKEQNENVIVHSGLVINVNTHECYLNEKQLSLTPT
                     EFSILRILCENKGNVVSSELLFHEIWGDEYFSKSNNTITVHIRHLREKMNDTIDNPKY
                     IKTVWGVGYKIEK"
     gene            724..>839
                     /locus_tag="ACG8LA_003072"
     CDS             724..>839
                     /locus_tag="ACG8LA_003072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance histidine kinase
                     VanS"
                     /protein_id="HFQ0205265.1"
                     /translation="MVIKLKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRS"
BASE COUNT          285 a          154 c          178 g          222 t
ORIGIN      
        1 tataatctga taaattatta agggcaaact tatgtgaaag ggtgataact atgagcgata
       61 aaatacttat tgtggatgat gaacatgaaa ttgccgattt ggttgaatta tacttaaaaa
      121 acgagaatta tacggttttc aaatactata ccgccaaaga agcattggaa tgtatagaca
      181 agtctgagat tgaccttgcc atattggaca tcatgcttcc cggcacaagc ggccttacta
      241 tctgtcaaaa aataagggac aagcacacct atccgattat catgctgacc gggaaagata
      301 cagaggtaga taaaattaca gggttaacaa tcggcgcgga tgattatata acgaagccct
      361 ttcgcccact ggagttaatt gctcgggtaa aggcccagtt gcgccgatac aaaaaattca
      421 gtggagtaaa ggagcagaac gaaaatgtta tcgtccactc cggccttgtc attaatgtta
      481 acacccatga gtgttatctg aacgagaagc agttatccct tactcccacc gagttttcaa
      541 tactgcgaat cctctgtgaa aacaagggga atgtggttag ctccgagctg ctatttcatg
      601 agatatgggg cgacgaatat ttcagcaaga gcaacaacac catcaccgtg catatccggc
      661 atttgcgcga aaaaatgaac gacaccattg ataatccgaa atatataaaa acggtatggg
      721 gggttggtta taaaattgaa aaataaaaaa aacgactatt ccaaactaga acgaaaactt
      781 tacatgtata tcgttgcaat tgttgtggta gcaattgtat tcgtgttgta tattcgttc
//
LOCUS       DAZKKZ010000207          799 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.220, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000207 DAZKKZ010000000
VERSION     DAZKKZ010000207.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 799)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 799)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..799
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.220"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..660
                     /locus_tag="ACG8LA_003073"
     CDS             <1..660
                     /locus_tag="ACG8LA_003073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-guided endonuclease TnpB family protein"
                     /protein_id="HFQ0205266.1"
                     /translation="YISLLCKEEIIELPKTNSTIGIDLGIMDFAILSDGQKIDNNKFT
                     SKMEKKLKREQRKLSRRALLAKNKGTNLFEAKNYQKQKRKVARLHEKVMNQRTDFLNK
                     LSTEMIKNHDIICIEDLNTKGMLRNHKLAKSISDVSWSKFVTKLQYKADWYGRKIIKV
                     DKWFPSSQICSECGHKDGKKSLEIREWTCPVCHTHHDRDINASINILTEGLRLHSMGL
                     A"
BASE COUNT          293 a          124 c          149 g          233 t
ORIGIN      
        1 tatatttctt tgttgtgtaa agaagaaatt atcgaattac ctaaaactaa ttccacaatt
       61 ggtattgact taggtattat ggactttgcg attctttctg atggacaaaa aattgataat
      121 aataaattca cgtccaaaat ggaaaagaaa ctaaagcgtg aacaacgcaa attgtctagg
      181 cgtgctttat tggctaaaaa taaaggtacc aatctatttg aagctaaaaa ttatcaaaaa
      241 caaaaacgca aagtagctag attgcatgaa aaagtaatga atcaacgtac tgattttctg
      301 aataagttga gtacagaaat gatcaaaaat cacgatatta tctgtattga agacttaaac
      361 acaaaaggta tgttgcgaaa tcataaatta gctaaaagta tttctgatgt ttcttggtca
      421 aagtttgtga ctaaattaca atacaaggct gactggtatg gacgaaaaat catcaaagta
      481 gataaatggt ttccgtctag tcagatttgt tcagagtgcg gacataaaga tggcaagaaa
      541 tctcttgaaa ttcgagaatg gacttgtcct gtttgtcata ctcatcatga tcgtgatatc
      601 aatgctagta tcaatattct gaccgaaggt ctaagactac attctatggg attggcttag
      661 atccaatcat caagaaccgt aggaactacg gggatagctt ggtaaataag agacaccgct
      721 gttagtaaag aaatacgcta tcaagtatgc tctattccca agaagctccc acttcaagcg
      781 ttaagaaccg tcaggttta
//
LOCUS       DAZKKZ010000208          798 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.221, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000208 DAZKKZ010000000
VERSION     DAZKKZ010000208.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 798)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 798)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..798
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.221"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(333..446)
                     /locus_tag="ACG8LA_003074"
                     /pseudo
     CDS             complement(333..446)
                     /locus_tag="ACG8LA_003074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315396.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
BASE COUNT          286 a          125 c          127 g          260 t
ORIGIN      
        1 tctttttcgt tgctttgctc ataaaaatct gcatattcat cactaatatt ttttctaata
       61 aattcttcca tcataaagat cacctcgaaa agagtatacg aacaaacgtt ctttttgtaa
      121 aggtggaatt tattatacta aataaatagg tgaacaagta cttgtgccaa attatgtgcc
      181 aaaaaaaatc gaatttaata aaacacaaac aaaaagaaat cctattatga taacatttct
      241 tataataaca aacacaacag aagacgtgta atagttagtc aggaacgtac aaataacccc
      301 tgtatccttt gcggtacagg gggttatttt gtataagtag acattgtagt ttctaaactg
      361 ctatgtccta aacgtttcga tacgctaagt atatttactc cttgataaag taaaatagat
      421 gcatgcgtat gtcttagtcc atcaataaac agtcgaagag aaaataggga aaaattgatt
      481 actaaagaaa aacttactag gtcgacggtg tagttgattt tcatacttca atagattcga
      541 attaaacgat ttcgattggc ttataccagt cctatccaac gaaagatata tcgttcttaa
      601 ctctagcggt ataacttgaa gctttacgta aagccaatgg gaatgaactg gagatgactt
      661 tttattattt ttagtaatag ctgatgggtt aatacttaca actttccttt tcaaagtacc
      721 atataaaaaa acggtggggt tgtttagcga aataaaggat ctaagccaat agcttagatc
      781 ctttattcta tgctttat
//
LOCUS       DAZKKZ010000209          787 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.222, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000209 DAZKKZ010000000
VERSION     DAZKKZ010000209.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 787)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 787)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..787
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.222"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..716
                     /locus_tag="ACG8LA_003075"
     CDS             <1..716
                     /locus_tag="ACG8LA_003075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF4767 domain-containing protein"
                     /protein_id="HFQ0205267.1"
                     /translation="KKRILVTIGLAFLLAGCTNGNESKKESTKETAKATVATTTTTST
                     ESKSTAASTETADTSTSSESSKTTETTQTSTSSSSVEASSSSSESSEQVEQTLWNADK
                     SAQLEAFMTKWGQTMGQQYKSYTNQMSVDLYGLKVPQAILNGEWKMAIGGVPVSAEWS
                     ESGTGQADYQITAVYSDAETEPYLKKHVYLFGFQQNQPKVLVTQQNQGNPDNYLYFNE
                     TANNELKNGFNQIVYGQAN"
BASE COUNT          282 a          151 c          159 g          195 t
ORIGIN      
        1 tgaaaaaaag gattttagta acaattggtc tagctttttt gttagctggt tgtaccaacg
       61 ggaatgaatc gaaaaaagaa tcaacaaaag aaacagcgaa agcaacagtt gcaactacta
      121 caacaactag cacagagagc aagtcaactg cagcaagtac agaaacagca gatacctcta
      181 cttcgtcaga gtcttccaaa acgactgaaa caactcaaac atctacttca agttcttctg
      241 tagaggcttc atcttcctct tcagaaagca gcgaacaagt tgaacaaaca ctgtggaatg
      301 cagacaaatc cgcacaatta gaggcattta tgaccaaatg gggccaaaca atgggacaac
      361 aatacaaaag ttatacgaat caaatgagtg tggacttata tggtcttaaa gtccctcaag
      421 ctattttgaa cggggagtgg aagatggcta ttggtggagt gcctgtttct gcagaatggt
      481 cagaaagtgg gacaggtcaa gcagactatc aaatcacagc cgtctattcc gatgcagaga
      541 cagaaccata tctgaaaaag cacgtctatc tattcgggtt tcagcaaaat cagccaaaag
      601 tattggtgac acaacaaaat caggggaatc ccgataatta tctttacttc aacgagacag
      661 cgaataatga attgaaaaat ggctttaatc aaatcgttta tggacaagca aattaatgag
      721 ataaacaagg ggttgtgaca tgtcttttat cacaacccct tgctcagttt atttgttagt
      781 cttttat
//
LOCUS       DAZKKZ010000210          780 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.223, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000210 DAZKKZ010000000
VERSION     DAZKKZ010000210.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 780)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 780)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..780
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.223"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            10..720
                     /locus_tag="ACG8LA_003076"
                     /pseudo
     CDS             10..720
                     /locus_tag="ACG8LA_003076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312603.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182-like element ISEfa7 family transposase"
BASE COUNT          259 a          144 c          157 g          220 t
ORIGIN      
        1 tgaaaacgaa tgcaaggagt gatagctatg atgtctaaaa acaatacgaa tggtagaaat
       61 caatttgcga tgcttacgat tgatgatcta gttcctcaag atcatctcgt tcgaaagatt
      121 gatgccgcgc ttgattttga atttatttat ccaatcgtcg aagccactta ctccgattta
      181 ggtcgcccaa gtatcgatcc agtgattctg atcaaattgg tgtttattca gtatttattc
      241 ggtatccgtt ccatgcgaca aaccattaag gaagtcgata ccaatgtcgc ttaccgctgg
      301 tttttaggct actccttcga ggagaaaatc ccccatttct caacttttgg aaagaattat
      361 gttcgccgat ttagagaaac gacggtgttt gaggatattt ttgcctatat tttagaacaa
      421 gcagttaaag caggttttgt aacagaggat aatttgtatc tggattctac ccacatcaaa
      481 gctaacgcca ataaacataa gtttacgaaa gaaatgaccc atgatgaagc gaaagcctat
      541 caggatgaat tagaagatga gatcaatcgt caacgaatag aggctggaaa acgccctttt
      601 actttggact tagaaaagga agtgaagctg aaagaaagaa aaataagtaa agctgatccg
      661 gaaagcggct actacgtcaa aggcgaacga gaaaaacaat ttgcttattc tgtccatact
      721 taatgcgacg acaatggatt tattcttagc acaatcatca ctcctagaaa tattcatgac
//
LOCUS       DAZKKZ010000211          760 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.224, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000211 DAZKKZ010000000
VERSION     DAZKKZ010000211.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 760)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 760)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..760
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.224"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..337)
                     /locus_tag="ACG8LA_003077"
     CDS             complement(<1..337)
                     /locus_tag="ACG8LA_003077"
                     /inference="COORDINATES: protein motif:HMM:NF024673.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HFQ0205268.1"
                     /translation="MTATEIRNNKLKKKISTIFFTNKQRYGATKIHQVLLKEGISVSL
                     KHVQKLMKQLNLRSIVVKKYRPQRSNKPIISKENLLNQDFSTETICEKWAADITYIPT
                     KKNGWCYLSS"
     gene            complement(448..702)
                     /locus_tag="ACG8LA_003078"
     CDS             complement(448..702)
                     /locus_tag="ACG8LA_003078"
                     /inference="COORDINATES: protein motif:HMM:NF013677.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFQ0205269.1"
                     /translation="MTRYEENFKQMIVELNQTGRSVRGLAKEYGLSEATIYKWKNLYL
                     PDQSTGLTGKEVAELRKENARLNEELEILKKAAAIFSRKT"
BASE COUNT          225 a          135 c          112 g          288 t
ORIGIN      
        1 ttgaagataa gtaacaccaa ccatttttct tagtaggaat gtacgtaatg tcagctgccc
       61 atttctcaca gatcgtttca gtagaaaagt cctgatttaa gagattctct tttgaaatga
      121 tcggtttatt agacctttga ggtctatatt ttttaactac aatcgacctt aaatttaatt
      181 gtttcattag cttttggaca tgtttaagag atactgaaat cccttctttt aataaaactt
      241 gatggatctt tgtggcacca tagcgttgtt tattcgtaaa aaaaattgtt gaaatcttct
      301 ttttcaactt attatttctg atttctgtag ctgtcaacgg tttattctta taaaaataat
      361 agacacttct agggatttct aataaccgac ataacaaaga aacagtgtaa tccttacacc
      421 atttttcaat aaattgaaca agcgaattta ggttttccga gagaatatgg ctgcggcttt
      481 ttttaagatt tcaagttcct catttaaacg agcattttct tttctcagtt cagctacttc
      541 ttttccagtc agtcctgtgg actgatcagg taaatataaa ttcttccatt tgtaaatcgt
      601 tgcttcagat aagccatatt ctttcgctaa ccctcgaaca gaacgtccag tttgattcag
      661 ttcaacaatc atttgtttaa aattttcttc atatcgggtc ataaaaattc atcctctcgt
      721 agataagttt aatttattct tgtctctacg aaaagctgtc
//
LOCUS       DAZKKZ010000212          758 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.225, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000212 DAZKKZ010000000
VERSION     DAZKKZ010000212.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 758)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 758)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..758
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.225"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(243..392)
                     /locus_tag="ACG8LA_003079"
     CDS             complement(243..392)
                     /locus_tag="ACG8LA_003079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0205270.1"
                     /translation="MTFTKTNMQYRVAFDTTSNRFMAIDAQNENNVAFGITIEQAVRA
                     LNESR"
BASE COUNT          267 a          118 c          109 g          264 t
ORIGIN      
        1 tatattaaat attatacaga taataacgga atattatcat cgaaacagct aacaaaattg
       61 tcataaaaaa cgagatggtt gatattagaa cttgtgtttt tgtttaggtc tagagataaa
      121 gagagacaat ttccaaatat atgtaatgaa tacaaaaaga cgtttgtcgc ggattaccgt
      181 tacaaacgtc ttttattgat tttccgagat ctcatcagtc gccatttgga atggttcact
      241 ccttatctag attcgtttaa tgctcggact gcttgttcga ttgtaatacc aaacgcaacg
      301 ttattttcgt tttgtgcatc aatcgccata aaacggttag aagttgtatc aaaagctacg
      361 cggtattgca tatttgtttt tgtaaacgtc ataaaattca tctcctttgt aatgtaattt
      421 agttcttgaa agtttccttt aaactttcga acttatacca agtttagcat cgtacgtttt
      481 ttgatgcaat taaaaagcat ttatcatttt ccttatttat tttttcttaa atggtttagc
      541 tattttcttt taatccgata agtagcccaa tcatcaaggt tacaaatact attgcttgaa
      601 tataaatcat atgctcacct ctttataaat aacttagcaa tataaagaaa aaaacgcacg
      661 aacaacatag gaatataaac aaacgttttt gtcacaacgt ctaagatcgt gttaaaaaat
      721 agttatctaa aaagcagaaa gatactcaaa ataaaaaa
//
LOCUS       DAZKKZ010000213          755 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.226, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000213 DAZKKZ010000000
VERSION     DAZKKZ010000213.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 755)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 755)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..755
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.226"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..>755
                     /locus_tag="ACG8LA_003080"
     CDS             <1..>755
                     /locus_tag="ACG8LA_003080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="IS982-like element ISEfm1 family transposase"
                     /protein_id="HFQ0205271.1"
                     /translation="KQRDTVIIACVIWGIINGYTSQRATYRAVCSVLFPNGDFPSRSR
                     FTRLSSNLAYTIKIIRYFFIKKLTKGELVGIIDSFPSPLCKPVRNRQAKLLNQIAKVG
                     YNSTKKSYFYGLKIHMIVTKTGFPITYSITNPGVHDVKVLETLSEEANLPNILGDKGY
                     ISHKIHEKLALKGITISVPPRKNMDKSEKLDHSLLGKQRKTVETVFSSLEKLGCQNFN
                     SRSVKGLESRFESILLAYSVLLSRAQRRFEGTL"
BASE COUNT          254 a          137 c          139 g          225 t
ORIGIN      
        1 tgaagcaacg cgatacagtg attattgctt gtgttatatg gggcataatt aatggctata
       61 ctagccaaag agccacgtat agagcggttt gttccgtctt atttcctaat ggtgactttc
      121 ctagtaggag tcgattcact cgcttaagtt caaacttagc ttacactatc aagattattc
      181 gatacttttt catcaagaag ctcaccaaag gtgaactagt cggaattata gatagttttc
      241 ctagtccatt atgtaaacca gttagaaata gacaagcaaa actattgaat caaatagcca
      301 aagttggcta taactcaaca aaaaaatctt atttttatgg tcttaaaatt catatgatcg
      361 ttactaagac tggctttccg attacttact caatcacgaa tccaggtgtc catgacgtga
      421 aagtgttaga gactttatcg gaagaagcga atcttcccaa tatcctaggg gacaaaggat
      481 atattagcca taaaatccat gaaaagcttg cccttaaggg cattactata tccgttccgc
      541 cacgtaaaaa catggataaa tcagaaaaac tagaccacag cttacttgga aaacaaagaa
      601 aaacagttga gactgttttt tcttccttag aaaaattagg ttgtcaaaat ttcaactcac
      661 gttctgttaa agggctagag agtagatttg aaagcatatt actggcttac agtgttctat
      721 taagtcgagc acaacgacgt tttgaaggaa ctttg
//
LOCUS       DAZKKZ010000214          738 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.228, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000214 DAZKKZ010000000
VERSION     DAZKKZ010000214.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 738)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 738)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..738
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.228"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            390..>738
                     /locus_tag="ACG8LA_003081"
     CDS             390..>738
                     /locus_tag="ACG8LA_003081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007208413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFQ0205272.1"
                     /translation="MKILIVDDEASILDIVEAYLSAKGYQVFRALSGNEALTKVDVVQ
                     PDLIVLDLMLPGLSGLEVCKKIRDSSTVPIIMLTAKTAEKDILEGLSLGADDYITKPF
                     SPKELVVRVETVLR"
BASE COUNT          228 a          135 c          170 g          205 t
ORIGIN      
        1 ctttccttta aaatgattca tcgtcattcc tcctgctatc tttttctatt attctacctt
       61 atttgatagt agatttaaaa ctttgcaaca gaaccagaaa tgaatattgt aaaaaatgat
      121 taggtagcgt ttattaatcc atgttcataa cttaagactt tagacaacat cccaaaagca
      181 gaagattcta ctacgcctga caaagtgatg acctttagtg gcatgggaaa catggtcgcc
      241 attgacggca aacagttcga catggaccgg atcgatttac gcgctaaggt cggggaaaag
      301 gaagtttggg agattaaaaa cacacgggac atgatgggtc aagttttagt agaatgaaga
      361 taccaacgaa attggaggag aaagattacg tgaagatttt aattgtggac gacgaagcaa
      421 gcattctgga tatcgtggaa gcctatttga gtgcaaaagg ctatcaagtg tttcgcgctt
      481 tgagcggaaa cgaggcttta acaaaggttg atgttgtcca acctgatttg attgtgttgg
      541 atctcatgct gcctggttta tctggcctcg aagtctgtaa aaaaataagg gactcctcca
      601 ctgtaccgat tatcatgttg actgcgaaaa cagccgaaaa agatatcttg gaagggttaa
      661 gcctgggggc tgatgactac atcacaaaac cattcagccc gaaagagctg gttgttcggg
      721 tcgaaaccgt tttacgcc
//
LOCUS       DAZKKZ010000215          735 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.229, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000215 DAZKKZ010000000
VERSION     DAZKKZ010000215.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 735)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 735)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..735
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.229"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            27..>735
                     /locus_tag="ACG8LA_003082"
     CDS             27..>735
                     /locus_tag="ACG8LA_003082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HFQ0205273.1"
                     /translation="MTYTHLTTDELVIIESYFKMNQSVAKTAHCLNRSRQTIHKVYLF
                     FKQGKSALEYYQQYKKNKSNCGRRPLVLPEEQSEYIQRKVVQGWTPDVIVGRAAFPIS
                     CSARTIYRMFKKGLFDSSDLPMKGKRKPNGHQERRGKQTFRRSIHEREKDYSQFSNEF
                     GHLEGDTIVGLKHKSAVITLVERLSKVIITLKPCGRQAIDIEKKLNQWFESVPKNLFK
                     SITFDCGKEFSNWKQISN"
BASE COUNT          260 a          127 c          139 g          209 t
ORIGIN      
        1 caaagaatta taaggagtga gtacaaatga cctataccca tcttacaacg gatgaacttg
       61 taataataga gtcttatttc aaaatgaatc aatctgttgc taaaactgcc cattgcttga
      121 atcgttcaag acaaacgatc cataaagtat atctgttctt caagcaagga aaatcagcct
      181 tagaatatta tcaacagtat aagaaaaaca aatcaaactg tggtagacgt ccgcttgttt
      241 tacccgagga acaatcagaa tatattcaaa gaaaggttgt tcaaggatgg acacccgatg
      301 tgattgttgg tcgtgcagcg tttcctatta gttgttctgc tcgtaccatt tatcgtatgt
      361 tcaaaaaggg gctatttgat tcttctgact taccgatgaa aggcaagcgt aaaccgaatg
      421 gacatcaaga aagacgtgga aaacaaactt tccgccgctc tattcatgaa cgtgaaaagg
      481 attatagcca attctcaaat gagtttggtc accttgaagg tgacactatc gtaggtctga
      541 aacataaaag tgctgtaatt accttagttg aacgattatc aaaagttatc atcacattga
      601 aaccgtgtgg tagacaagcg attgatattg aaaaaaaatt aaatcaatgg tttgaatctg
      661 taccgaaaaa cctattcaaa tccatcactt ttgattgtgg aaaggaattt tcaaattgga
      721 aacagatcag taatg
//
LOCUS       DAZKKZ010000216          696 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.230, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000216 DAZKKZ010000000
VERSION     DAZKKZ010000216.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 696)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 696)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..696
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.230"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(54..629)
                     /locus_tag="ACG8LA_003083"
     CDS             complement(54..629)
                     /locus_tag="ACG8LA_003083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytS/YhcK type 5TM receptor domain-containing
                     protein"
                     /protein_id="HFQ0205274.1"
                     /translation="MNKNKMATRVLTVMALCIGINYIGGTIALWLRLPIYLDSIGTIF
                     AGALLGPVPGMLTGLSSGILSGVTTDIFSLYYSPIQILTGLLAGLILPRYLGKDKNSL
                     KLLLLALILSVPGTIVSSIITVQLFGGITSSGSSMIVQLLHGLGLSQTTSVILVQAGT
                     DYLDRLLSIVVVSLVITMLPQRLIYSKRKIG"
BASE COUNT          230 a          151 c          124 g          191 t
ORIGIN      
        1 aatgaaaaaa cagagccaga ttagcattat tttgctaatc cagctctgtt tattcagcct
       61 atttttcttt ttgaatatat caagcgttgg ggcaacatag tgatgactaa tgaaacaacg
      121 acgatagaca acaagcgatc aaggtagtct gtacccgcct gtaccaagat cacacttgtt
      181 gtctgactta aacctaaccc atgtaatagc tgaacgatca tactggatcc tgaggaggtg
      241 atcccgccaa ataactgaac ggtaatgatc gaagaaacga tcgttccagg taccgacaaa
      301 atcaaagcga gtaataacag tttcaagctg tttttatctt tgccgagata tcttggcaaa
      361 atcaatccag caagcaagcc tgtgagaatt tggattggcg aataatacag agaaaaaata
      421 tctgtagtca ctccacttaa aataccgctg gacaatcctg tcagcattcc aggtacaggc
      481 ccaagcaatg caccagcaaa aatcgttccg atagaatcga gatagattgg caaacgaagc
      541 cataaagcaa tcgttcctcc aatataattg atcccaatac acaaagccat cactgtaagt
      601 acgcgagttg ccattttgtt tttattcatt ttgttagccc atctttaacc tttccaaatc
      661 tttcataatc gtttcttctt gtgcatttaa aagaac
//
LOCUS       DAZKKZ010000217          694 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.231, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000217 DAZKKZ010000000
VERSION     DAZKKZ010000217.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 694)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 694)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..694
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.231"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(304..603)
                     /locus_tag="ACG8LA_003084"
     CDS             complement(304..603)
                     /locus_tag="ACG8LA_003084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0030153 - bacteriocin immunity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HFQ0205275.1"
                     /translation="MSKSEEIENMVLKLYDLVLNPEIKEKERILLIDAKTGLEKGQYY
                     PKVINNLERSLRPLAIRGELSKPVSPFYMEISTIGKFEKELGRGMASAPITFGHL"
BASE COUNT          225 a          121 c           73 g          275 t
ORIGIN      
        1 ttttcgcata tattcatttt attttactta ttgctttcat tttttcaatc tatatttcca
       61 atttttaact tacaaaaatg caacattaat aaataacgat agtttcataa aatacacttt
      121 taattaacat tattagttta tactagctgt ttttgtgtta attaaaggat aaaatacaat
      181 ataaagaaac atctgtttct ttatttagaa taaaaaaata cagactctgt tcaaataaat
      241 gaacctagcc tgcattatga gattgactat actttttaat tcattgagat gaataactcg
      301 tttttataaa tgcccaaaag taatcggtgc cgaagccatt cctcgaccta attctttttc
      361 aaattttcct attgttgata tctccatata aaacggtgat actggtttag acaattctcc
      421 cctgattgct aacggacgta aactacgttc caaattattt atgactttag gataatactg
      481 acctttttct aagcctgtct ttgcgtctat caaaagtata cgttcctttt ctttgatctc
      541 tggatttaaa acgagatcat ataattttag taccatgttt tctatttctt cacttttaga
      601 catcacgatt tcctcccaaa aatatatttc ttcccactac attctataaa caaagtatac
      661 gctacatcta gattttttta aatcattact ggat
//
LOCUS       DAZKKZ010000218          618 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.233, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000218 DAZKKZ010000000
VERSION     DAZKKZ010000218.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 618)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 618)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..618
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.233"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..>618
                     /locus_tag="ACG8LA_003085"
     CDS             <1..>618
                     /locus_tag="ACG8LA_003085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0205276.1"
                     /translation="QDIEERKNAMHGQAKSAEELINQKRHEAKYTPEAMNREEIMLRK
                     RVEGRTGANIDGKEALTKERIQEAKNSNTGLEKLVKENPQNSTSSHGGRSVDVRENIQ
                     GSLNGHVGRNVDVRENLQSSSNAQGTKTIDVRENLQSSSTSQPKTVDVRENVQNSTSS
                     QGFKSVDVRENVQGSSASQPKTVDVRENVQSSTSSQGFKTVDVREN"
BASE COUNT          250 a           91 c          143 g          134 t
ORIGIN      
        1 caagatattg aagaacgtaa aaatgctatg cacggtcaag ctaagtctgc tgaagaatta
       61 attaatcaga agcgtcatga agcgaaatac acgcctgaag caatgaatcg cgaggaaata
      121 atgttaagga aacgtgtaga agggcggaca ggcgctaata ttgacggaaa agaagcgttg
      181 accaaagaaa gaattcaaga agctaaaaat tcaaatacag gattagaaaa attagtcaaa
      241 gaaaatccac aaaattctac aagtagtcat ggtggccgat cagtagatgt ccgagaaaat
      301 attcaaggtt cactgaatgg tcatgttgga cggaatgttg atgtaagaga gaatttacaa
      361 agttcttcaa atgctcaagg tactaagaca attgatgttc gagaaaatct gcaaagtagc
      421 agtacaagtc aaccaaaaac agtagatgtt cgagaaaatg tacaaaattc tacaagtagt
      481 caagggttta aatcagtgga tgtccgagag aatgtgcaag gtagcagtgc aagtcaacca
      541 aaaacagtag atgtccgaga aaatgtacaa agttctacaa gtagtcaagg attcaaaaca
      601 gtagatgttc gggagaac
//
LOCUS       DAZKKZ010000219          598 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.234, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000219 DAZKKZ010000000
VERSION     DAZKKZ010000219.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 598)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 598)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..598
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.234"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..288
                     /locus_tag="ACG8LA_003086"
     CDS             <1..288
                     /locus_tag="ACG8LA_003086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase"
                     /protein_id="HFQ0205277.1"
                     /translation="QEYTIKLHTDVNPQTLRSAKSKTISIKKTDQKELFLPAKGFENC
                     SHTPSAKQIHYQISRIMNDDVKMYRAKKDYEFTQQMIENQQKRQQNFEMEF"
BASE COUNT          220 a          113 c          108 g          157 t
ORIGIN      
        1 caagaataca cgattaaact tcatacggat gtgaatcctc aaactttacg tagtgcgaaa
       61 agtaaaacaa tttctattaa aaagactgat cagaaagagt tatttctacc ggcaaagggt
      121 tttgaaaatt gttctcatac accttctgct aaacagattc actatcaaat cagtcgcata
      181 atgaatgacg atgtaaaaat gtatcgtgct aaaaaggatt atgaattcac acaacaaatg
      241 attgaaaatc agcaaaaaag gcaacaaaat tttgaaatgg aattctgaat gggcttgtta
      301 gtggactttc cagttttttg cctatgaaga gttgcttgga aagaagcagt ttttaggaca
      361 tacgccagct acccatctac ttgccagtca atccgccccg ctcacgctag gctactttct
      421 ggcaagtcag atggcgggta aatctctgag ggagcaagct ccctacagac tccctcccaa
      481 aaaaagaaag gtggaagaaa aaaatgaact atccatattt taaagtctcg gcttcagaag
      541 aaactaaaga aatattcaac aatttttaca accaaaacaa aggaattttt ggttcaaa
//
LOCUS       DAZKKZ010000220          576 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.236, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000220 DAZKKZ010000000
VERSION     DAZKKZ010000220.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 576)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 576)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..576
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.236"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..90)
                     /locus_tag="ACG8LA_003087"
     CDS             complement(<1..90)
                     /locus_tag="ACG8LA_003087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017370594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HFQ0205278.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNISYRE"
     gene            166..495
                     /locus_tag="ACG8LA_003088"
                     /pseudo
     CDS             166..495
                     /locus_tag="ACG8LA_003088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136908.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
BASE COUNT          199 a          108 c          105 g          164 t
ORIGIN      
        1 ttcacgatag ctaatgttat aacgaagata gtagcccacg gctacaataa tcacatcctg
       61 ctgaaattgc tttcctttaa aatgattcat cgtcattcct tctgctatct ttttctatta
      121 ttctacctta tttgatagta gatttaaaac tttgcaacag aaccaacgac agaataccaa
      181 atttcagaga ttaacaactt actggagaaa aagcaaaaag aactcatcaa gctggctaat
      241 aagggtcaag attatgaaca tctagcagat gagattgatg agctgagaga caagcgacag
      301 ctccttttag tagaagatgc ctccctcagt ggcgagaacg agcgaatcaa tgagctgatt
      361 gaatttatcc gcaagaacaa attccgtacc ttagagtacg atgataagct tgtaaggaag
      421 ataatccaga gcgttacagt ctatgaagaa cacttcgtca tatccttcaa atctggcatc
      481 gaaatggaaa tatgaaaacc agaagtaaat agcccatgac tctacagtag agtcgtgggt
      541 tttcttttgc ttgctgatta taataatatt ttaata
//
LOCUS       DAZKKZ010000221          552 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.238, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000221 DAZKKZ010000000
VERSION     DAZKKZ010000221.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 552)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 552)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..552
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.238"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..>552
                     /locus_tag="ACG8LA_003089"
     CDS             <1..>552
                     /locus_tag="ACG8LA_003089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0205279.1"
                     /translation="RTLGFQVLFGSLILTIVFLKWKTSNKKSMWSLVGIVLIIFTVTA
                     ATEANYSHKIQSYKGRLVMTKKDVTRYTSSRTGGLYDYAPLDALKYKDHLKKHEVKVG
                     DRWENASHKAYNSKIVYTVEDADEQNITLPVFNYWGTVVKVNGKKSTIENDNGLVSIK
                     GTGKRTIVEVSSTYPTTMILSLLI"
BASE COUNT          202 a           76 c          108 g          166 t
ORIGIN      
        1 agaaccttgg gttttcaagt gctttttggt tcattaatct taaccatagt gtttttaaag
       61 tggaaaacaa gcaacaaaaa aagtatgtgg agccttgtag gaatagttct tattattttt
      121 actgtgactg cagcaacaga agcaaattat tcgcataaaa ttcagtcgta taaaggtcgt
      181 ttagttatga ccaaaaaaga tgttacacgt tatacatcct caagaactgg aggcctatat
      241 gactatgcac cattagatgc attgaaatat aaagatcatt taaagaaaca tgaagtaaaa
      301 gttggtgatc ggtgggagaa tgcatctcat aaagcatata attccaaaat agtctataca
      361 gtagaagatg ccgatgagca aaatatcaca ttacctgtat tcaattattg gggaacagtt
      421 gtgaaagtaa atgggaaaaa gagcactata gaaaatgaca atggtttagt gtctattaaa
      481 ggtacgggga aaagaactat agttgaggtt tcatctacgt atccaactac gatgattcta
      541 tctttattaa tt
//
LOCUS       DAZKKZ010000222          534 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.239, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000222 DAZKKZ010000000
VERSION     DAZKKZ010000222.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 534)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 534)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..534
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.239"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..>534
                     /locus_tag="ACG8LA_003090"
     CDS             <1..>534
                     /locus_tag="ACG8LA_003090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="phage tail tip lysozyme"
                     /protein_id="HFQ0205280.1"
                     /translation="DGFKACTDPRQAAYAFERNYERPAATHPERQDYAVNWYNKFKDL
                     KPGGATGEAGLKHLESLIGQRIGNGQCYGLSAEYSGYLGGCGMGAGTKYGLTHVIGNT
                     SAASDIGIAYDWSAVGWKVIQNPRYDQLVVGAIINWARGGQVGSWFADGTYGHTGVIR
                     GLANGRMQTYEQNTELG"
BASE COUNT          163 a           80 c          137 g          154 t
ORIGIN      
        1 tgatggattt aaggcctgta ctgatccaag acaagcagca tatgcttttg aacgaaacta
       61 tgaacgtccg gcagcgacac atcctgaacg tcaagattat gcagttaact ggtataacaa
      121 atttaaagat ttaaaaccag gaggagctac tggagaagca ggactaaaac atttagagtc
      181 tttgattgga caacgaattg gcaatggtca gtgttatggc ttgtctgcag aatattcagg
      241 atatctgggt ggttgtggca tgggtgctgg aacaaaatat ggtttaactc atgtgatagg
      301 aaatacttct gcagcatctg atattggtat tgcctatgat tggtctgctg ttggttggaa
      361 agtgattcaa aaccctagat atgatcaatt agtagttggt gcaattatta attgggcaag
      421 aggtggacaa gtgggttcat ggtttgcaga tggaacttat ggacatactg gcgttatccg
      481 aggcttagct aatggtcgta tgcaaactta tgaacaaaac acagagttag gtat
//
LOCUS       DAZKKZ010000223          511 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.240, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000223 DAZKKZ010000000
VERSION     DAZKKZ010000223.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 511)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 511)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..511
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.240"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..342
                     /locus_tag="ACG8LA_003091"
     CDS             <1..342
                     /locus_tag="ACG8LA_003091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0205281.1"
                     /translation="DNIRDKKASLKSLKDTWLDLSEDNPYSQFLITVMAGVNQLERDL
                     IRMRQREGIELAKKEGKFKGRLKKYHKNHAGMNYAVKLYKEGNMTVNQICEITNVSRA
                     SLYRKLSEVNN"
BASE COUNT          206 a           68 c           93 g          144 t
ORIGIN      
        1 gataacatac gagataaaaa ggcaagttta aaatcactaa aagatacatg gcttgattta
       61 tcagaagata atccatacag ccaattctta attactgtaa tggctggtgt taaccaatta
      121 gagcgagatc ttattcggat gagacaacgt gaagggattg aattggctaa gaaagaagga
      181 aagtttaaag gtcgattaaa gaagtatcat aaaaatcacg caggaatgaa ttatgcggta
      241 aagctatata aagaaggaaa tatgactgta aatcaaattt gtgaaattac taatgtatct
      301 agggcttcat tatacaggaa attatcagaa gtgaataatt agccattctg tattccgcta
      361 atgggcaata tttttaaaga agaaaaggaa actataaaat attaacagcc tcctagcgat
      421 gccgaaaagc cctttgataa aaaaagaatc atcatcttaa gaaattctta gtcatttatt
      481 atgtaaatgc ttataaattc ggccctataa t
//
LOCUS       DAZKKZ010000224          508 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.241, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000224 DAZKKZ010000000
VERSION     DAZKKZ010000224.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 508)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 508)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..508
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.241"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
BASE COUNT          227 a           70 c           81 g          130 t
ORIGIN      
        1 attccttagg cagcttttgc tgtgtagaaa ggaataaata ataacgaaag ttcaaaagct
       61 aatgccgact attctagaca ttaaagaaga cgaaaacgaa cgataaagaa agaaaagtta
      121 tgaataatcg tttattgaaa aaaacttgaa aaaatacaaa aaattcgttg accaagctaa
      181 atttagttgg tatattatta cttgtccaaa agacagaaga aaatatttat tcaaaaacat
      241 aacaaaaaag ttattgacat gttactaacg acatgataag ataactgagt cgttaaaaaa
      301 gaaccacttg cgaagcttga ttctatcgaa aaaaacttca aaaaagttct tgacaaataa
      361 caaacgataa gttatgataa atgagttgcc gaaagatttc gaaaaacgaa atcgaaaaaa
      421 acttttaaaa aagagttgac aatcgcttgt ctctctgata tgatataaaa gttgctacgg
      481 cagccaaaaa tgaatcggga aacactct
//
LOCUS       DAZKKZ010000225          500 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.242, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000225 DAZKKZ010000000
VERSION     DAZKKZ010000225.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 500)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 500)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..500
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.242"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
BASE COUNT          168 a           96 c           57 g          179 t
ORIGIN      
        1 tttttaaaaa taagaatgct aaatcactct acaataacgg cgaaagcaca aaaaataaaa
       61 aaattattac gttattaaaa aaacagatga aagatcaggt tttattagat ctcattcttt
      121 catcacttga agggatttaa tgaactactt tttcctcttt gtcgttttta tatattcgta
      181 ttccttcaaa cagtaggata gcctctttca atgcttgata tttgaactgt ccgttactta
      241 aaaatttaga tgtgccgccc tcttcctaga acatattctt ttttactttt tcattaattg
      301 acagaccaat cgaacgaaac tgtaaatttc gataggataa tgattggtca aactcattca
      361 ttttcaagac atctcgattc atattcaaga taggaatctt tttatcaaca tcactttatt
      421 cgtattttcc tctaccataa aagcttcacg ctccacaaaa ttgttttata cactactatt
      481 cagcccattc aacgaccaat
//
LOCUS       DAZKKZ010000226          487 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.243, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000226 DAZKKZ010000000
VERSION     DAZKKZ010000226.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 487)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 487)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..487
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.243"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..>487)
                     /locus_tag="ACG8LA_003092"
     CDS             complement(<1..>487)
                     /locus_tag="ACG8LA_003092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFQ0205282.1"
                     /translation="IHRRFYTSICHQKITTDTTEFKYHEVDAKGIIRQKKLYLDPFMD
                     MFNSEILSYRISEKPNALAVMEGLEEAIQTTNDCPYRRTFHSDQGWAYQMKAYRNKLK
                     EYKIFQSMSRKGNCLDNSLMENFFGLLKQEIFHGKVYNCFEELKSAIDSYIYYYNNER
                     IK"
BASE COUNT          142 a           92 c           86 g          167 t
ORIGIN      
        1 gttttatccg ttcattattg tagtaataga tatagctatc gatggctgat tttaattcct
       61 cgaaacagtt ataaactttc ccgtgaaaaa tctcttgttt taataagcca aaaaaattct
      121 ccataagtga attatctaag cagttccctt tccgagacat gctttgaaag attttgtact
      181 ccttcaattt gtttctataa gctttcattt gatacgccca accttgatct gagtgaaacg
      241 tacgacgata gggacaatcg ttagtggtct ggatagcttc ctccaaacct tccattaccg
      301 ctaatgcatt gggcttttca gagatacgat aggataaaat ctcactattg aacatatcca
      361 taaaaggatc tagatacaat ttcttttgac ggataatgcc tttggcatcc acttcatggt
      421 atttaaattc agttgtatcc gtcgtgattt tctgatggca gatactggtg tagaaacgac
      481 gatggat
//
LOCUS       DAZKKZ010000227          470 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.246, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000227 DAZKKZ010000000
VERSION     DAZKKZ010000227.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 470)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 470)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..470
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.246"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..>470
                     /locus_tag="ACG8LA_003093"
     CDS             <1..>470
                     /locus_tag="ACG8LA_003093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="IS3-like element IS1485 family transposase"
                     /protein_id="HFQ0205283.1"
                     /translation="ALSKRGIQISRRKISRIMKNRGLKSSYTVAYFKVHHSTCNEAKT
                     TNVLNRKFLRDNPLEAIVTDLTYVRVGKKWNYVCFILDLFNREILGYSCGEHKDAVLV
                     KKAFSRIKQPLTEVEIFHTDRGKEFDNQAIDELLTTFDINRSLSHKGCPFDNAV"
BASE COUNT          167 a           78 c           88 g          137 t
ORIGIN      
        1 aagccttatc aaaacgaggc attcagatca gccgacgaaa aattagtaga atcatgaaaa
       61 atagaggatt aaaatcgagc tatactgttg cttattttaa agtacatcat tctacttgca
      121 atgaagccaa aacgacaaac gtattgaatc gtaaattctt aagagacaac ccattagaag
      181 cgatcgtaac agacttgact tatgtacgag tcgggaaaaa atggaattat gtctgtttca
      241 ttttggatct gttcaatcga gaaattctcg gctattcttg tggagaacat aaagatgccg
      301 ttctagtaaa aaaagcattt agccgtatca aacaacctct gacagaggtt gagatttttc
      361 atactgatcg tggaaaagag tttgataacc aagctattga tgaattatta acaacttttg
      421 acatcaatcg atcattgagt cataaaggct gtccttttga taatgccgta
//
LOCUS       DAZKKZ010000228          419 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.249, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000228 DAZKKZ010000000
VERSION     DAZKKZ010000228.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 419)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.249"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..372
                     /locus_tag="ACG8LA_003094"
     CDS             <1..372
                     /locus_tag="ACG8LA_003094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005576 - extracellular region [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HFQ0205284.1"
                     /translation="TSDSSDSSTTTSDSTDTSASSDSTDTSSTTSDSSDSSTSSDSTD
                     TSSTTSDTRHASVSFSKTSSDNRTNFNLTNKTSNDNGNKSKRALPKTGSQSNNWITLA
                     GVILLVIGLRITFMSYKKSKR"
BASE COUNT          163 a           87 c           72 g           97 t
ORIGIN      
        1 acaagtgata gctcagattc atctaccact acaagtgata gcacggacac gtcagcttca
       61 agtgacagta cagatacatc ctctaccaca agtgatagct cagattcatc aacttcaagc
      121 gatagtacag acacgtcgtc taccacaagc gatacacgtc atgcaagtgt ctccttctca
      181 aaaacaagtt cggataacag gacgaacttt aacttaacta ataaaacaag caatgacaat
      241 ggaaacaaat caaaaagagc acttcctaaa actggaagtc aatcgaataa ttggataaca
      301 ctcgcaggcg ttatattact tgtaatcggt ttaagaatca cttttatgag ttataagaaa
      361 tcgaaaaggt aaaaaaatat tcaagataaa aaagagcaac gtcgctaacg gacgttgct
//
LOCUS       DAZKKZ010000229          408 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.250, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000229 DAZKKZ010000000
VERSION     DAZKKZ010000229.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 408)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 408)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..408
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.250"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..>408
                     /locus_tag="ACG8LA_003095"
     CDS             <1..>408
                     /locus_tag="ACG8LA_003095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="HFQ0205285.1"
                     /translation="QDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHTTIYRWVQEY
                     GKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDIWLRKKRDTQA
                     AYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKL"
BASE COUNT          138 a           67 c           83 g          120 t
ORIGIN      
        1 gcaggatgtg attattgtag ccgtgggcta ctatcttcgt tataacctta gctatcgtga
       61 agttcaagaa atcttatatg atcgtggcat taacgtttct catacgacga tttatcgttg
      121 ggtgcaagaa tatggcaaac tactctatca aatttggaaa aagaaaaata aaaaatcctt
      181 ttattcatgg aaaatggatg aaacgtacat caaaattaaa ggaaaatggc attatttgta
      241 tcgagccatc gatgcagatg gtttaacctt ggatatttgg ttacgtaaaa aacgggacac
      301 acaagcagcc tatgcttttc ttaagcggtt agtgaagcag tttgatgaac cgaaggttgt
      361 agtcacagat aaagccccct ctattacaag tgcctttaag aaactaaa
//
LOCUS       DAZKKZ010000230          391 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.252, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000230 DAZKKZ010000000
VERSION     DAZKKZ010000230.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 391)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 391)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..391
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.252"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
BASE COUNT          135 a           56 c           57 g          143 t
ORIGIN      
        1 ttattgcttt tgcaaaattt atttacctgt tttctggatc aacgatagtg tacattatgc
       61 tatccttgtt tggattttag gacgtttaaa gaggcacttt tttacataac ttaatccata
      121 gaccttttaa gcatgctgtg agataataat aaagaagagt ttaaagcgca ccccaaacca
      181 cttccccata agtgtattac gctttaaact cttttatatt tgaattcact aagaagcata
      241 ccatatattt gaatttacta agaagcatac catatttttg aaaaaaagtg agaaaaaagg
      301 cttataatta ggatttagag taattaatta gatgtttatt ttataggact gatactatag
      361 attacaaata gtatcgtatt tcgcaatctt a
//
LOCUS       DAZKKZ010000231          368 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.denovo.253, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000231 DAZKKZ010000000
VERSION     DAZKKZ010000231.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 368)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 368)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..368
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.denovo.253"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            82..>368
                     /locus_tag="ACG8LA_003096"
     CDS             82..>368
                     /locus_tag="ACG8LA_003096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HFQ0205286.1"
                     /translation="MNDSIKKMLRLIEKDLMITEVSYETFQKKKTLIVDAVFSPAPHT
                     CRNCGSTVVDGNGKVIVVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCR"
BASE COUNT          130 a           59 c           76 g          103 t
ORIGIN      
        1 attttaggta ttaaaaaaca tatcgttctc tagtatgatt aaatcacgac aaaataaaca
       61 actgagagga cgatatgcta tatgaatgat tctatcaaaa aaatgctgcg attaatagag
      121 aaagatttga tgattacaga ggtctcttac gagacctttc agaagaaaaa gacgttgatc
      181 gtcgatgctg ttttctcacc tgctccccat acctgtagaa attgtggttc tactgtggta
      241 gatggaaacg ggaaagtaat tgtagtgaaa aatgggaaga aggaaacgat tgtccgcttt
      301 gaacaataca atcacatgcc tttggttatg cgcttaaaaa agcagcgcta tacctgtaaa
      361 aactgtcg
//
LOCUS       DAZKKZ010000232        25907 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.guided.041, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000232 DAZKKZ010000000
VERSION     DAZKKZ010000232.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 25907)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25907)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25907
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.guided.041"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(172..2310)
                     /locus_tag="ACG8LA_003097"
     CDS             complement(172..2310)
                     /locus_tag="ACG8LA_003097"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006486 - protein glycosylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFQ0205287.1"
                     /translation="MQKKEIAVFIDQITRERATGDLLIVGWAIDEVTKEIPTIKVEKE
                     NVIAEATHVVRLDINHLYNLDVKTQSGFKVRLSGKMRGKAILDFQTARHQNGIAVKLN
                     GKYPYDDGIESSWERKKRLLKKGINYARTHGVKKAIRRVKLELKPGSIDYAEWISRHE
                     KPDLKEQRKEAQGFAYRPLISILMPVYNVEIKWLEKCIDSVLDQTYDHWELCISDDAS
                     TDPAIRKCLESYQAKDDRIKVVFRKENGHISLATNSALEIAEGEFIALLDNDDELPPF
                     ALYEVAKVLNVHPELDVIYSDEDKIDADGNRFDPHFKADWSPDTLMGNNYISHLGVYR
                     TSIVKELGGFRKGYEGSQDYDLVLRVTEQIPADHIYHIDRVLYHWRTIPGSTASNGEA
                     KSYIYDSGVKALTDALSRRNIKGSVRPGRISGFYEIAYDVLQEDLVSVIIPTKNGYED
                     LKTCVDSIIEKTSYSNYEIIIADNGSTDPKMQELFAEYKHQLKDRFIVELIDIPFNYS
                     RINNLAAEKANGKYFLFLNNDTEVIEPDWMTVMVSYAQFDRIGCVGAKLFYPDDTTQH
                     AGVLLGIGGVAGHALNNYDRTHCGYFGRLVIDVNYLAVTAACMMVKAADFNAVNGFDE
                     TLEVAFNDVDLCLKVYELGRYNVYAHQAELYHFESKSRGYEDTPEKQRRFAGEIKKMQ
                     DKWPAYIAHDPFYNDNLTKEGIGDFSLRPD"
     gene            complement(2349..3935)
                     /locus_tag="ACG8LA_003098"
     CDS             complement(2349..3935)
                     /locus_tag="ACG8LA_003098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFQ0205288.1"
                     /translation="MKYDFEMDLDEQSSVGKIAAQIKPGSKVLEFGPGNGRLTKHLIG
                     AKQCEVSIVELDKELFDFVSEFAQDGFYGDIESFEWANYYAGQTFDYVLFADVLEHLV
                     DPGKTLKKVREFLNEEGEILITFPNLAHNSVMIDLFNNQLPWASYGLLDETHNSFYTH
                     DGFQKVFEKAGLFINIEDYLYLAVGDTELKSTYEELPEAVRYDFKMRPFGEVYQYFFS
                     LMKHPVAQSSIAEPQNSNYVKVLEVTQQTKQDETIQQIPFNNFTGENETLSFPVSETT
                     ERMVFRFAQQPSFIEFSAEAAGEKLTFIDSNAVVKTVNDCYLFDGKELPEFVLTDISG
                     KEVTIHCHYRFIGELTPTMKELLETIRPMAEVTKQLSEKNDELERENHHLLEENTRLD
                     HTLKTTTNRYCTLLESDEWTIKHRLGRRKKETSKKIQEKELSICIDEKIWDAETKILK
                     IIGWGIANSDRQPLSYKLSADQSPFFEAIPVSREEVNQAEQLAKGTEAGFELRILCEQ
                     ERSFLVEAVAQNGQSWIIEM"
     gene            complement(3925..5145)
                     /locus_tag="ACG8LA_003099"
     CDS             complement(3925..5145)
                     /locus_tag="ACG8LA_003099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0205289.1"
                     /translation="MTEYAIRLKDITKSYNMYAKPSDRFREALNPFKKSYHDVFYALK
                     NVNVEIKKGEMIGFVGENGSGKSTMLKIITGVLTPTSGTMEIEGKISALLELGSGFNP
                     EYSGYENIYLNGMVLGFSREEVDEMVDDIIEFADIGDHIYQPVKTYSSGMFVRLAFAV
                     AINVNPDILIVDEALAVGDLEFQLKCMEKFTEIKNSGKTILFVSHDISSIRRFCDRSY
                     WLKNGEVVEYGDTMEVTTNYENFLKKKSVKTVDRNKNQVERFAAPDIVDVTKAELLDK
                     DKNPVDMLEQGEKLYVKVTYEVKDDTIKNPVLGIALRTVDNFYVCGLNTLLDGIKIPW
                     KKGENIFYLEYEKLGLLAGEYYFDVAVFEENATVPLVYKTKYMNLFVSGSYIGEGIVV
                     LDHKWEEGTHSNEI"
     gene            complement(5157..5963)
                     /locus_tag="ACG8LA_003100"
     CDS             complement(5157..5963)
                     /locus_tag="ACG8LA_003100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFQ0205290.1"
                     /translation="MFKDLYLFMKDIYQNRKLLLQFSINDFKSRYAGSFLGILWAFIN
                     PLFTVLIYWLVFGVGLKAQMIDAKYPFIVYLVTGMIPWFFFSDAFASTTVVFREYTYL
                     VKKVVFNIRILPTTKILSNLYTHLFFILIGIAVALINGIYPSAMSLQLIYYLFCMCAF
                     LTGLTWLTASIQPFLPDIMQLITIVLQLIMWTLPILWSPNQFDSGLVSILKLNPLYYV
                     VQGYRESFLSEAWFWEHGTYTLYFWVFTLVMFVIGSAVFRRLKPHFSDVL"
     gene            complement(6173..7453)
                     /locus_tag="ACG8LA_003101"
     CDS             complement(6173..7453)
                     /locus_tag="ACG8LA_003101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EpaQ family protein"
                     /protein_id="HFQ0205291.1"
                     /translation="MEIIQAIVQKFVNKMSVGFLLLLLTLVFFVWTAGLGFPATLFIY
                     NNSSLLIAFSVAILLILNVYKAKGVDFLYLGVALALFIFFSYFRELRNESLFGDLLFP
                     LIILFCLVIKWIEWTKWDRGIYLIVFSVFLGITLYRVFTEIQVPEGQSIWAPGNSLSD
                     IWINTNIIGSSLMTLALLISGFASSFERWYVRIIGAVAVVAAFLGIWVCQSRGALVAL
                     IVFAILDLLPKSLMRVIRAPFIAYTVTILLALPISYLAAVSEKVNLFTGREDIWHKFY
                     QTLGEKSEQILLGMKTFIFQRGNQFLGNHNSYNSILNIYGLIGFGIAALLLILFIGRL
                     TLKADLSNGQMTFIWAFFAVMMQSFMEDTLTSYPWVPIIYILLAMAVHRYDEPEVAEE
                     FYVMEEAYDDMTYDDTSYEEQPDSAHSSRIQRYH"
     gene            complement(7497..9530)
                     /locus_tag="ACG8LA_003102"
     CDS             complement(7497..9530)
                     /locus_tag="ACG8LA_003102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0205292.1"
                     /translation="MEKQTRSARRKEKPKANQADSNLVLDLFLKLRYLIGVLVIVVIV
                     TFNLNGSSLGVWDKYVSQRDDGKKTDVIFGQNREVRSDEWLVQTPFYLSQAEEDFPLV
                     NEDYSLNGQNMIIAYNSPVKDITVIGKPFNWGFFFLGRDRGLSFYWAMKLVVMVLLGF
                     EVLMILTKRKKALSLIGAFALTFSPAVQWWFMQHVGDLIFFTLGLMTAFYHYFYNHDK
                     KWLRTLMMLLVVIFGIGFILVIYPAHQVMLAYLLIFYFVGLLIYYSKKVSWDLLDVVL
                     IGGAVLFIGGVMVHFWLTSKDALLASLNTLYPGKRVSTGGKWTIGEFFSFLTNWKIPF
                     EDINYSNNSEVALFYHFFPTVFLASPFVLFGKKDSEQKLLGRILMIFCLFSIFWITVG
                     LPKWLAEITLLSYVPPLRAILTFSFAACLLSIWFIAYIWREDVIPIWYKFILLAVNAW
                     SYFYAITHSKMDNYFSDFETIAVAVLGTVILAFALFGWRRLFYLAFAALVIVSGFFVN
                     PVVEGTGAIFEKTLAKEIQKIDQQDPGKVWLSEDELYNFTPTLGVKSFNTVRFYPDIA
                     AWKKIDPKEEYEKYYNRYAHTRAFIAKEDTKFILDRPDMFSVTLNFEDAEKLGIDYVI
                     SKRPLTDYNQLYEAQFTQLYGPDKDGYMIFKVEYPDYPDVPQTQTQENQLVVQ"
     gene            complement(9564..10415)
                     /gene="rfbD"
                     /locus_tag="ACG8LA_003103"
     CDS             complement(9564..10415)
                     /gene="rfbD"
                     /locus_tag="ACG8LA_003103"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008831 - dTDP-4-dehydrorhamnose reductase
                     activity [Evidence IEA];
                     GO_process: GO:0009243 - O antigen biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HFQ0205293.1"
                     /translation="MFLLTGGNGQLGTELRHLLDEKNLQYVSTDAKDLDITDAEKTMA
                     YITELKPDVIFHCAAYTAVDKAEEEAKELDEKINVDGTRNVALAAKAVNAQFVYISTD
                     YVFDGKNKNVEYEVDDQTNPLNEYGRTKLLGEKAVEEILEDYYIIRTSWVFGIYGHNF
                     VFTMQRLAETRDKLTVVNDQFGRPTWTRTLAEFMVYVIEEKAPFGIYHLSNENSCSWY
                     EFAKEILKDTDVEVAPVTSEEFPQKATRPQYSVMSLKKTEELGFVIPTWQEALAQMLE
                     AAKKMNK"
     gene            complement(10513..11541)
                     /gene="rfbB"
                     /locus_tag="ACG8LA_003104"
     CDS             complement(10513..11541)
                     /gene="rfbB"
                     /locus_tag="ACG8LA_003104"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008460 - dTDP-glucose 4,6-dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009225 - nucleotide-sugar metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HFQ0205294.1"
                     /translation="MKNIIVTGGAGFIGSNFVHYVVNNHPEVHVTVLDKLTYAGNKEN
                     LAGLPSDRVELVVGDVADAELVDRLVKEADAVVHYAAESHNDNSLKDPFPFVQTNIIG
                     TYTLLEACRKYDVRYHHVSTDEVYGDLPLREDLPGHGEGEGEKFTAETPYNPSSPYSS
                     TKAGSDLLVKAWVRSFGLRATISNCSNNYGPYQHIEKFIPRQVTNILSGIRPKLYGEG
                     KNVRDWIHTNDHSSAVWLILTKGRIGETYLIGADGEEDNKTVMELILEMMGQPKDAYD
                     HVNDRAGHDLRYAIDSTKLREELGWKPEFTNFRDGLADTIKWYEEHEDWWKKEKEAVE
                     AAYAKNGQ"
     gene            complement(11563..12135)
                     /gene="rfbC"
                     /locus_tag="ACG8LA_003105"
     CDS             complement(11563..12135)
                     /gene="rfbC"
                     /locus_tag="ACG8LA_003105"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010771301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008830 - dTDP-4-dehydrorhamnose
                     3,5-epimerase activity [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HFQ0205295.1"
                     /translation="MKVTDTKLTDVKIVEMDVFGDHRGFFTESYSKAKFAEHGLKYDF
                     VQDNHSLSAEAGVLRGLHFQKGEAAQTKLIRVVTGAVLDVVVDIRKGSPTYGQWDGFI
                     LSEHNHRQLLVPKGYAHGFVTLTPNVNFLYKCDNYYNAEADGGIAFDDPDLAIDWPID
                     PSRAIMSEKDHRHPTLKEFEAENPFVYGEI"
     gene            complement(12149..13015)
                     /gene="rfbA"
                     /locus_tag="ACG8LA_003106"
     CDS             complement(12149..13015)
                     /gene="rfbA"
                     /locus_tag="ACG8LA_003106"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008879 - glucose-1-phosphate
                     thymidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0045226 - extracellular polysaccharide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HFQ0205296.1"
                     /translation="MKGIILAGGSGTRLYPLTKATSKQLMPIYDKPMIYYPMSTLMLA
                     GIKEILIISTPQDTPRFKELFGNGNDLGLQIEYAVQESPDGLAQAFIIGEEFIGDDSV
                     CLVLGDNIYYGGGLSKMLQRAASKDTGATVFGYHVNDPERFGVVEFDENMQALSIEEK
                     PAQPKSNYAVTGLYFYDNEVISIAKGIKPSERGELEITDVNKAYLDKGKLSVELMGRG
                     FAWLDTGTHESLLEASTFIETIEKRQNLKVACLEEIAYRMGYIDKEQLLALAQPLKKN
                     QYGQYLLNLAAE"
     gene            complement(13115..13822)
                     /locus_tag="ACG8LA_003107"
     CDS             complement(13115..13822)
                     /locus_tag="ACG8LA_003107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFQ0205297.1"
                     /translation="MRSVCIATFNGGRYLREQLDSILSQLSAEDEVVISDDGSVDDTW
                     DILTEYAEKDKRIQLFSGPRQGLIANFGYAIQQTKGDLIFLADQDDVWLETKVKKITD
                     YFEQNPDQLVVVSDLIIVDSELQEIHDSYFSFRNSKEGWLNNVIRSHYIGAGMAFRSS
                     LKPDILPIPSEVPMHDMWIGLLGGKKTGFLREPLTLYRRHDLNASEIETHSKLRQKIS
                     WRVHLITALIKRKWFKR"
     gene            complement(13827..14654)
                     /locus_tag="ACG8LA_003108"
     CDS             complement(13827..14654)
                     /locus_tag="ACG8LA_003108"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFQ0205298.1"
                     /translation="MKPEILVVVVLYQQLFSQSPAYGPLSKALSEKQIQLIIYDNSPQ
                     RQQNELFEKENIVYHHDPQNPGLAVAYNFALSQADEGTRCLVTLDQDTRLVDDYFELL
                     RKVTFTDECVAAVPMIFSGSRQVSPLYSDRYINRTAQAVEVEGPTAERIMAINSGVAW
                     SVKFLKKIGGFNPAFSLDFLDHWLFWKVDQLEKTVEILPVRMEHDLSVLDYEKVSSNR
                     YRSILQAENRFYHEYDQRHLSSHRRQLLLRTAKQFLTVKNRHIWRMTLRSYVKNWKV"
     gene            complement(14654..15454)
                     /locus_tag="ACG8LA_003109"
     CDS             complement(14654..15454)
                     /locus_tag="ACG8LA_003109"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFQ0205299.1"
                     /translation="MNNKLNQPILISIVTANSDKIFRTLDNFISTVKDETAVKIRIFD
                     NNSLPEYKKRLTEYRKYPYIDIYFHDENSGFGYGHNHNLIASDSRYGIICNPDILVDE
                     ETVTALVLLLKEHPECAMLAPKILNEDGTTQHLIREQLAVFDYVLRFVPFKWVKKKFD
                     KRLAVFECRGLPTDANSYVRMISGSFMVADIDKFKEIKGFDERFFMYFEDNDLCLSFE
                     KAGYKLLYTPFYAVIHFYGKGAHRNAKLFRVFLTSMMKFFNKWGWRFF"
     gene            complement(15447..16586)
                     /locus_tag="ACG8LA_003110"
     CDS             complement(15447..16586)
                     /locus_tag="ACG8LA_003110"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MraY family glycosyltransferase"
                     /protein_id="HFQ0205300.1"
                     /translation="MLVSFSMVIRFFLTILLSLILTPVFKIISVQTGMVDKPNERRIN
                     KVPMPSAGGLPIFISFVISTLFLFRKIIPQSYIVPILIASLVIIVTGVLDDKYELTPK
                     QKSIGILIASLIIYFVADIRIDSFTLPFIGYIQLGWLSFPVTIFWIFGITNAVNLIDG
                     LDGLAAGISLIGLITIGIIGYFFLHASTVYIPVVIFCLVASIIGFFPYNFYPAKIYLG
                     DTGALFLGFMMAVLSLQGLKNVTFVSSISLLIVMGVPVTDTFFAIIRRKANRVSFSTA
                     DKKHLHHRLISLGFTHKGAVLTIYAMALMFSFTAMVMNYTGRIGTIILIIAMLFAAIL
                     LFELIGLINEKHQFILKTLRFLGNKEYRTQVKQKYLKKWNRHIDE"
     gene            complement(16791..17984)
                     /locus_tag="ACG8LA_003111"
     CDS             complement(16791..17984)
                     /locus_tag="ACG8LA_003111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005336078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFQ0205301.1"
                     /translation="MKEKRRDNKGRILHTGESQRTDGKYLYKYVDALGNTKYVYAWRL
                     TPTDPTPKGKREKPSLRELEQQIRRDIEDGIDSTGKKMTLCQLYAKQNAQRTNVKKST
                     QKQREQLMRLLKEDKLGARSIDTIKPSDAKEWALRMKDKGFSYNTINNHKRSLKASFY
                     IAIQDDYVRKNPFDFKLSEVIENDTKEKVALTEEQEQALLSFIKTDNVYHKHYDDVLI
                     LLKTGLRISELCGLTVADIDFKNEVVIIDHQLLKSKEQGYYIETPKTKSGIRQVPLSK
                     ETIQAFQRVINSRPKIKSIEVDGHSGFVFINPKGNPKVAIDYNALFIRMVKKYNKHHK
                     DNPLPHITPHTLRHTFCTRLASKNMNPKDLQYIMGHSNISITMNWYAHASIDTAKSEV
                     QRLIA"
     gene            complement(18063..18269)
                     /locus_tag="ACG8LA_003112"
     CDS             complement(18063..18269)
                     /locus_tag="ACG8LA_003112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HFQ0205302.1"
                     /translation="MSNTQDIPVWEKYTLTIEEASKYFRIGENKLRRLAEENKDAGWL
                     IMNGNRIQIKRRQFEKVIDKLDAI"
     gene            complement(18262..19404)
                     /locus_tag="ACG8LA_003113"
     CDS             complement(18262..19404)
                     /locus_tag="ACG8LA_003113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005336080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HFQ0205303.1"
                     /translation="MNNLEFALEMKNKRLASGLSQGELASLTHVSRYSINRFENGKAN
                     ASKETQNIILRCLNYYICDKPFYLLVDYLSVRFPTTDALEVIRKVLGMKADYFIHYDY
                     GYYGYKEHYAYGEIKVMASDDEHMGVFLELKGAGSRNMEYVLQAQNRDWYSFLNRCLD
                     CGGVIRRFDLAINDMCGLLDIPVLSEKYRNGGAECRCKNYENVQGGKLSGKNRNLAST
                     LYIGSKASTKYFCLYEKQKEQATKKKHTDIINRFEIRLRDKKAVQAVEELLLTYNPHG
                     LVFYLITDFVEFPDYPLWEIFISHDSLPFEMNPVPVNMERTLQWLERQVMPSIVMIEE
                     IDRLTGSNYMKMIDECTHLSEKQEMLVEQMCTDISDVIESEGVFYE"
     gene            19916..20551
                     /locus_tag="ACG8LA_003114"
     CDS             19916..20551
                     /locus_tag="ACG8LA_003114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFQ0205304.1"
                     /translation="MEGYAMKISHLGNNIQTIRKFRGMKQQELADKIGINMQSLSKIE
                     RGLNYPAYETLEKIMEVLDVTPNELLSGEWKYVNQSEKEVCQFLRAEERLNAELKHGH
                     YDNFFDSEEEWLEYELEKLREYITDYINGKSIEASDLYPIKEFIQHLKFQKLLDRYDD
                     LYSMDMFGESIEGHKYKTPYQVVKMINPNSKEDMELLREVLRNNNFDDEDE"
     gene            20687..20779
                     /locus_tag="ACG8LA_003115"
                     /pseudo
     CDS             20687..20779
                     /locus_tag="ACG8LA_003115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323349.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
     gene            20893..21528
                     /locus_tag="ACG8LA_003116"
     CDS             20893..21528
                     /locus_tag="ACG8LA_003116"
                     /inference="COORDINATES: protein motif:HMM:NF012655.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFQ0205305.1"
                     /translation="MARNKYPEETVKLILDVSTKMFCEKGYDNTSLQDIINETKLSKG
                     AIYHHFDSKEDILKAIFQRIGNENAVIFAKIRDNDSLNGLEKLREIFKTAVFNSNQSV
                     LLTVSPQLLNNPRFLAMQIEQMYEIVVPEFVEPVLEQGIKDKSLEIENSHEIAEVIMV
                     LSNVWLNPLVEMTDKEGMEKRCNTFNALLNGIGIDTLLDEETISAFIQFCK"
     gene            21635..22873
                     /gene="mef(H)"
                     /locus_tag="ACG8LA_003117"
                     /gene_synonym="mefH"
     CDS             21635..22873
                     /gene="mef(H)"
                     /locus_tag="ACG8LA_003117"
                     /gene_synonym="mefH"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_070509550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="macrolide efflux MFS transporter Mef(H)"
                     /protein_id="HFQ0205306.1"
                     /translation="MQAEKKLFNRDFILVVIGQIISLFGNAILRFALPYYLLKETGSS
                     ALFGIATACSFLPMVILSLVGGIIADRTNKRNIMVILDFVTAIIILVFYLSLGKIPII
                     PLFIVALMLLYGISGAYQPAVQASIPLLVSSDKLTVGNAIINQVNTLANFIGPAISGV
                     VFQFYGINPILIVSIICFTFSAIMEIFIHIPHQKRPREVGVIAVAKNDLKDSYTFLKK
                     EKPIFISVIFLVCIFNLVLSAVLIVGLPILISEVLKMPDTLYGFSQSALSLGGLCGGI
                     LTALVASKLKLKNLYTLLLICSVSVLLMGISLFLELPAIVSYWVVTVMCFVAMGVSTM
                     FVVQIYTLVQTQTPPQLVGKIMATLVAVAMCGQPIGQMVYGILFDVFIQETWVVMFVA
                     SIASIMISIYSKRIFQKLEI"
     gene            23100..23519
                     /locus_tag="ACG8LA_003118"
     CDS             23100..23519
                     /locus_tag="ACG8LA_003118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009588541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HFQ0205307.1"
                     /translation="MRTSSFEHIVRLQFNSLMLIVIKNKVKSRNRQLARHSKREVLFC
                     EIAETKQVERGTIDTCFYDCVSFKVLHFTIYVSDETLGTVLHRLSEKQRSAILLRYFQ
                     GMNDREISELYHVSRSAICSRRTRGLRKLKMLLSERK"
     gene            23524..23763
                     /locus_tag="ACG8LA_003119"
     CDS             23524..23763
                     /locus_tag="ACG8LA_003119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004609551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0205308.1"
                     /translation="MSKDYGYPSFELICKASSGDEMAVKEILKFYDGYISKLCLRPFY
                     HSESGKIIMQVDEELKGEIHTDMMKAILKFEIGVK"
     gene            complement(23988..24911)
                     /locus_tag="ACG8LA_003120"
     CDS             complement(23988..24911)
                     /locus_tag="ACG8LA_003120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HFQ0205309.1"
                     /translation="MKVWNKIKQNENLMRFIETTQKRITDSEMSTTSVVVAYYLLLSL
                     FPLIIAFGNILPFLHIDQETVLTYLREVIPETVYQFIGPAIKDLLTQSSGGLLSVSAL
                     AALWSASQSINALQIAMNKAYGVENRKNFLIVRFFSLIVIVLFMIAISGVTIVLGLGQ
                     LILDAIQPIVQIPVNFIDQFQTLKWPITLVALFVIMFLIYLIVPNAQLKLKTIIPGTI
                     FATVGWMLLSQVFSIYARYFATRISGYQIIGSFIVLMLWLNFAATIIILGGIINAVVQ
                     EYVTGHQIKKRRDPSRKWFNKLKTKFSHKKK"
     gene            complement(24943..25707)
                     /gene="map"
                     /locus_tag="ACG8LA_003121"
     CDS             complement(24943..25707)
                     /gene="map"
                     /locus_tag="ACG8LA_003121"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008377375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HFQ0205310.1"
                     /translation="MITLKSAREIEMMAESGALLADVHKNLRDFIKPGITSWDIEVFV
                     RNYIESHGGIAAQIGFEGYEYATCISINDEICHGFPRKKPLKNGDLVKVDMCIDLKGG
                     ISDSCWAYVVGESTPEIDRLMEVTKKALYIGIEQAQVGNRIGDIGHAIQTYVEGENLA
                     IVRDFIGHGVGPTIHEEPAVPHYGEAGKGLRLKEGMVITIEPMVNTGTWKMKMDPNGW
                     TAYTRDGGLSCQYEHTLAITKDGPRILTSQGEEGTY"
BASE COUNT         7832 a         5257 c         4465 g         8353 t
ORIGIN      
        1 aaatttgaaa agcaattttc gtgaatttct tcttatttct cggagttaaa cacttctgtc
       61 ccaacctcga cttatttttt tgagtcggca ccttctgcct ttttttgaca aaaaactata
      121 aaaagccgtt atgtgcgagc gaatcacaac ataacagctt tttattatag tttaatctgg
      181 tctcaacgaa aagtcgccga ttccttcttt tgttaaatta tcattgtaaa atggatcatg
      241 cgcaatatat gctggccatt tatcttgcat ttttttgatt tcaccagcaa aacgtctttg
      301 tttttctgga gtatcttcat aacctcttga tttagattcg aaatggtaca attctgcttg
      361 atgtgcatag acattgtaac gacccagttc ataaactttc aagcacaagt caacatcgtt
      421 gaatgctact tctaatgttt catcaaaccc gttaacagca ttgaagtcag ctgccttgac
      481 catcatacaa gctgcagtga ctgctaagta attgacgtca atgaccaatc ggccgaaata
      541 accacaatgt gttcgatcat agttattcaa tgcatgccct gcaacaccac cgattcctaa
      601 taatactcct gcatgctgcg ttgtatcatc tggataaaac agttttgctc ctacacagcc
      661 gattcgatca aactgtgcat aagaaaccat caccgtcatc caatctggct caatcacttc
      721 tgtatcgtta ttcaagaata aaaagtattt gccgtttgct ttttctgctg ctaaattgtt
      781 aattcgagaa taattgaatg gaatgtcaat caattctacg ataaagcggt ctttcagctg
      841 atgcttgtat tctgcaaata attcttgcat ttttggatct gtacttccgt tatccgcaat
      901 aatgatttca taatttgaat aagacgtttt ttcgatgatc gaatccacac aagtttttag
      961 atcttcatag ccattcttcg ttggaatgat cacactgacc aaatcctctt gcaagacgtc
     1021 ataagcaatc tcataaaatc cagaaattct gccaggacgt acgcttcctt tgatgtttct
     1081 tctagacagg gcatctgtca atgctttcac tccggaatca tagatataac ttttggcttc
     1141 gccattactt gcagttgatc ctgggatcgt ccgccaatga tacaagactc ggtcaatgtg
     1201 gtaaatatga tctgcaggga tttgttctgt cacacgaagg accaaatcat aatcttgaga
     1261 accttcatag cctttacgga aaccgccaag ttctttaaca atgcttgttc gatatacgcc
     1321 taagtgagag atataattat ttcccatcaa tgtatcaggc gaccagtctg ctttgaaatg
     1381 cggatcaaag cgattgccat ctgcatcgat tttatcttcg tcactgtaga tcacatccag
     1441 ttctggatgt acgtttagca cttttgccac ttcatataat gcaaatggcg gtaattcatc
     1501 atcattatct aagagtgcta taaattctcc ttctgctatt tccaatgcag aattagttgc
     1561 cagactgatg tgtccatttt cttttcggaa aacgactttg attctatcat cttttgcttg
     1621 ataggattcc agacactttc ggatagctgg atcagtagaa gcatcatcac tgatacatag
     1681 ttcccaatga tcatacgttt gatccagtac cgaatcaatg catttttcga gccatttgat
     1741 ttcaacgtta tagacaggca taagtatgga aatcaatgga cggtacgcaa atccttgtgc
     1801 ttctttcctt tgctctttca aatctggttt ctcatgacga ctgatccact ctgcatagtc
     1861 gatcgatcct ggcttcaatt ccaatttgac ccgacggatc gcttttttta cgccatgagt
     1921 ccttgcataa tttatccctt ttttcagtaa tctttttttt ctttcccatg aagattcaat
     1981 gccgtcatca taagggtatt taccgtttaa tttcacagct atgccatttt gatgtctcgc
     2041 tgtttggaag tctaagatgg cttttcctct cattttccct gataaacgta ccttaaaacc
     2101 gctttgggtc ttaacatcaa gattatataa atgattgata tccaatctta cgacatgtgt
     2161 tgcttcagca atcacatttt ctttttctac ctttatcgta gggatttctt tggtcacttc
     2221 atcaattgcc cagcccacaa taagcaaatc gccagtggcc cgttcacgag tgatttgatc
     2281 gataaatacg gcaatttctt ttttttgcac gattcgttta ctccttatct ttataagtta
     2341 atcattattt acatttcaat gatccatgat tggccatttt gagctactgc ttccactaag
     2401 aatgaacgtt cttgctcgca aaggattcgt aactcaaatc ccgcttctgt tccttttgcg
     2461 agctgttctg cttgattgac ttcttctcgt gaaacaggaa ttgcttcgaa aaatggcgat
     2521 tggtcagctg ataacttata ggacaagggc tggcgatccg aattagcgat tccccatccg
     2581 atgattttta atatttttgt ttctgcatcc cagattttct cgtcaataca tatagaaagt
     2641 tctttttctt ggattttttt cgaagtttct ttcttacgtc gtcctagtct atgttttatt
     2701 gtccattcat cactttccaa caatgtgcaa tagcgatttg tggttgtttt taacgtatgg
     2761 tctagtcttg tattttcctc aagaagatga tgattttctc tttctaattc gtcatttttc
     2821 tcagaaagct gctttgtgac ttcagccatg ggacgaatcg tttccaacaa ttctttcatt
     2881 gttggtgtca attccccgat aaagcgatag tgacaatgga tagtcacttc tttcccagaa
     2941 atatccgtta gaacgaactc tggtaattct ttcccatcaa acaaataaca atcatttact
     3001 gttttgacta cagcattcga atcgataaat gttagttttt ctccggcagc ttctgcgctg
     3061 aattcgataa agctaggttg ttgcgcgaag cgaaacacca ttctttctgt tgtttctgat
     3121 acggggaaac ttagtgtctc attttcccct gtgaaattat tgaatggtat ttgttggatt
     3181 gtttcatctt gtttcgtttg ctgggttact tctaacactt ttacataatt agaattttgt
     3241 ggctctgcaa tggaactttg tgctactgga tgtttcatca atgagaaaaa gtattggtag
     3301 acttcaccaa atggtcgcat tttgaaatca tagcgtacag cttccggcaa ttcttcataa
     3361 gttgatttta attctgtatc acctacagct aagtacaaat aatcttcaat attaatgaat
     3421 aatcccgctt tttcaaaaac tttttggaag ccatcatgag tataaaaaga attatgggtt
     3481 tcatctagga gaccataaga agcccacggc aattggttat tgaacaaatc gatcatgaca
     3541 gaattatgcg ccaagttagg gaatgtaatc aggatctctc cttcttcatt caaaaattct
     3601 ctgactttct tcaatgtttt tccaggatct accaaatgtt ctaaaacatc cgcaaacaag
     3661 acgtaatcaa atgtctgtcc agcataatag tttgcccact caaaactttc gatatcacca
     3721 taaaatccat cttgagcaaa ttcgctgaca aaatcgaaca attccttatc taactcaaca
     3781 atgctcactt cacattgttt tgctccgatt aaatgtttcg ttaatcggcc gtttccggga
     3841 ccaaactcta aaactttact tcctggtttg atctgtgcgg caatttttcc cacactgctt
     3901 tgttcatcta ggtccatttc aaaatcatat ttcattgcta tgagtccctt cttcccattt
     3961 atggtctaag accacgatgc cttctccgat ataagaaccg ctgacaaaca agttcatgta
     4021 ctttgtctta tataccaaag gaaccgttgc attttcttca aagaccgcaa cgtcaaaata
     4081 atattcacca gctaacaaac ctaacttttc atactccaga taaaagatat tctctccttt
     4141 tttccaagga atcttgatac catctagtag agtattaagt ccgcatacat aaaaattgtc
     4201 gactgttcgt agcgcaattc ctaaaaccgg atttttgatt gtatcatctt ttacttcata
     4261 agttacttta acgtatagtt tttctccttg ttccagcata tccaccggat ttttgtcttt
     4321 atccaacaat tccgctttcg tcacgtcgac gatatctgga gcggcgaacc gttctacttg
     4381 gtttttattc cgatccactg ttttaactga ttttttcttt aaaaagtttt cataattcgt
     4441 cgttacttcc atcgtatcgc catattcgac gacttctccg tttttcaacc aataggaacg
     4501 atcacaaaaa cgacgaatcg aactgatatc atgagaaacg aataaaatcg tctttcccga
     4561 gttcttgatt tctgtaaatt tttccataca ttttagttga aattcaagat cgcctactgc
     4621 caatgcttca tccacaatca aaatatcggg attcacattg attgctacag caaaagctag
     4681 acgaacgaac atcccgcttg aataagtttt tacaggttga taaatatggt ctccgatgtc
     4741 agcaaattca atgatatcat cgaccatttc atcgacttct tctcttgaaa atcctagaac
     4801 cattccattt aaatagatat tttcatagcc agaatactca ggattgaatc ctgatcctag
     4861 ttctagcaaa gctgagattt ttccttcgat ttccatcgtg ccggatgttg gtgtcagtac
     4921 tcccgtaatg attttcaaca ttgtagattt tcccgatccg ttttctccca cgaaaccgat
     4981 catctcacct ttttttattt ctacattcac gtttttcaac gcataaaata catcatgata
     5041 ggatttctta aaaggattga gggcttcacg aaatcgatcc gaaggttttg cgtacatatt
     5101 ataagatttt gtgatatctt ttagtctaat tgcatattct gtcatagcta ttctccttac
     5161 agcacatctg aaaaatgtgg tttcaatcta cggaacactg cagagccgat tacgaacatt
     5221 actaacgtga aaacccagaa atacaaagta tatgttccat gctcccagaa ccaagcttca
     5281 cttaaaaatg actcacgata accttgaaca acatagtaca gcggatttaa tttcaatatg
     5341 cttacaagac ctgaatcaaa ctgattaggg ctccataata tcggtaatgt ccacatgatc
     5401 aactgcagca cgatcgtaat taattgcatg atatcaggta aaaatggttg gatcgatgcc
     5461 gtcagccaag tcaatcctgt caagaaagca cacatgcaaa ataaataata aatcagctgt
     5521 aaagacattg ctgaaggata tataccattt ataagcgcga cagctatgcc aatcagaatg
     5581 aagaataagt gggtgtacag attggatagg attttcgtcg tgggcaagat acgaatattg
     5641 aatacgactt tctttactaa ataagtatat tcccgaaaaa caaccgtagt tgatgcaaat
     5701 gcatctgaga agaagaacca gggaatcatc ccggtaacta aatatacgat aaatgggtat
     5761 tttgcatcga tcatttgtgc tttcagtcca acaccaaata ccagccaata aatcaataca
     5821 gtaaatagcg gattgataaa cgcccataag attcctaaaa acgatcctgc atatcttgat
     5881 ttgaagtcat tgatcgaaaa ctgtagcaat aattttctgt tctgataaat gtccttcata
     5941 aataaataca aatctttaaa catttgtgtt cctccaagcg attttcagtg aattacagtc
     6001 aagtgccatt ttaccatatt tttggtaccg agctgcgttc ttatttcttt cttaattttc
     6061 tatgatacaa gattttctct aacgtttcta ttttacagaa gatgctagac aattgcaata
     6121 aaccaaaaaa ggctgcgacg gttgtcacag cctctctcgt attttgtgcc tatcaatgat
     6181 agcgttggat cctggaagaa tgagcgctat ctggttgttc ctcataagat gtatcatcat
     6241 aagtcatatc gtcatatgcc tcttccataa catagaattc ctccgcaact tctggttcat
     6301 catatcgatg aacggccata gccaacagga tataaataat cggaacccat gggtatgaag
     6361 tcaatgtatc ctccataaat gactgcatca tcaccgcaaa aaaggcccag ataaaagtca
     6421 tctgcccgtt ggataaatct gctttcaacg ttaagcgacc aataaaaagg ataagcagca
     6481 aagcagcaat cccaaatcct atcaatccat agatattcaa aatagaatta taactattgt
     6541 ggtttcctaa aaattggttt cctcgttgga agataaatgt tttcattcct agtaaaattt
     6601 gttcagattt ttctcctagc gtctgataga atttatgcca aatatcttct cgaccggtaa
     6661 acaaattgac tttttcagag acagccgcca gataagaaat cggcaaagct aaaagaatcg
     6721 taaccgtgta agcaataaat ggcgcacgaa tgacacgcat caacgattta ggtaaaagat
     6781 ccaatatcgc aaaaacaatc aacgcgacta atgcacctct agattggcag acccaaatcc
     6841 cgagaaaagc tgcaacaact gctactgcac cgatgattcg tacataccat cgttcaaaag
     6901 aactggcaaa tccactgatc aataaagcaa gagtcatcaa agaacttccg attatattcg
     6961 tattgatcca aatatcagaa agcgaattgc ctggagccca gatgctttgt ccttctggta
     7021 cttggatctc tgtaaataca cgatataacg tgattccgag gaagaccgaa aagacaatca
     7081 gataaatacc gcgatcccat tttgtccact cgatccattt aattactaaa caaaataaaa
     7141 taatcaaagg aaacagtaag tctccaaata aagactcatt tcttaattcc cgaaagtaag
     7201 aaaagaaaat gaaaagggca agcgcaacac ctagataaag aaaatcgacg ccttttgctt
     7261 tataaacatt taaaatgagc aaaatagcca cactaaaagc gataagtaat gaactattgt
     7321 tatatataaa caaagttgct ggaaaaccta accctgctgt ccaaacaaaa aagactagcg
     7381 tcagtaacaa aagcaagaaa ccgacactca ttttgttgac aaatttttgt acgattgctt
     7441 gaattatctc cactctcctt tctactaaca tttcaggatt attctcagct agcctattac
     7501 tgtacgacta gctgattttc ctgagtttgt gtttgtggta catctggata atccggatat
     7561 tctactttaa aaatcatata accgtcttta tccggtccat atagctgcgt gaactgcgct
     7621 tcatataatt ggttgtaatc agttaatggt cgtttactga tcacatagtc gatccctaat
     7681 ttttctgcgt cttcaaaatt caacgtgacc gaaaacatat ctggacgatc taaaatgaac
     7741 tttgtatctt ccttagcgat aaaagctctt gtatgagcat accgattata atacttctcg
     7801 tattcttctt tcggatcgat tttcttccat gcagctatat ctggataaaa gcgtactgta
     7861 ttgaaggatt tcactcccaa tgttggggtg aagttatata attcatcttc agacaaccaa
     7921 actttaccag gatcttgttg atcgattttt tggatttctt ttgccagtgt tttttcaaaa
     7981 atcgctcctg taccttctac gactggattg acgaaaaagc cagatacgat aactaaggcg
     8041 gcaaaagcga ggtaaaacaa gcgtctccag ccaaataatg caaaagctaa aatcactgtt
     8101 cccaacacag caactgcgat ggtttcaaaa tccgaaaaat aattatccat tttcgaatgc
     8161 gtaatcgcat agaaataaga ccatgcattt actgccaaca aaatgaattt ataccaaata
     8221 ggaataacat cttctctcca aatataagcg ataaaccaga tcgataataa acaagccgca
     8281 aaactaaaag taaggatggc tcttaatgga ggaacataag acagcagagt gatttctgct
     8341 agccattttg gcaacccaac ggtaatccaa aagatagaaa acagacaaaa aatcatcaaa
     8401 atacgtccca gtaacttttg ttcgctatct tttttgccaa ataacacaaa tggacttgct
     8461 aggaatacag ttggaaaaaa gtgatagaac agggccactt cagagttatt cgaatagttg
     8521 atatcttcaa aaggaatttt ccaatttgta aggaaagaaa aaaattcgcc aatcgtccac
     8581 tttcctccag tacttacccg ttttcctgga tataaggtat tcaaagaagc taacaatgcg
     8641 tcttttgacg ttagccagaa atgaaccatg actccgccaa taaataaaac tgcccctcca
     8701 atcaacacta catccaacag atcccatgaa actttcttgc tatagtaaat aagcaggcca
     8761 acaaaataaa aaatcagcaa gtacgccagc atcacttgat gggctgggta aatcactaaa
     8821 ataaacccaa taccgaaaat aaccaccaaa agcatcatca acgttcgtag ccatttttta
     8881 tcatgattgt agaaataatg ataaaaagca gtcatcagtc ccaaagtaaa gaaaatcaaa
     8941 tcgcccacat gttgcatgaa ccaccactgg actgctggag aaaatgtcag cgcaaatgca
     9001 ccgattagcg atagagcttt ttttctcttc gttaatatca tcagtacttc gaatccaagc
     9061 aagaccatga cgactaattt catcgcccaa taaaaggaaa gtcctcgatc tcttccgagg
     9121 aaaaagaatc cccagttgaa tggttttccg ataaccgtaa tatcctttac aggagaatta
     9181 tacgcaatga tcatgttttg tccgtttaat gaataatcct cgttcaccaa cggaaagtcc
     9241 tcttcagctt gtgagaggta aaaaggtgtc tgcaccagcc attcgtctga ccgcacttcc
     9301 cgattctgtc caaaaatcac atcagttttt ttcccatcgt ctctttgcga cacatattta
     9361 tcccaaacac caagtgaact tccgtttaaa ttaaaagtaa cgatgaccac gatgactaaa
     9421 acgccaataa gatagcggag ttttagaaac aggtcaagca ccaaattcga atctgcctgg
     9481 ttcgcttttg gcttttcttt tcgtcgtgca cttcttgttt gtttttccat atcatgctcc
     9541 aaattctatt tgataaaagg aaattactta ttcatttttt tggcagcttc cagcatttgc
     9601 gcaagtgctt cttgccaagt tggtatgaca aatcctaact cttctgtctt tttcaggctc
     9661 atgactgaat actgcggacg tgttgctttt tgcggaaatt cttctgacgt aacaggtgca
     9721 acttctacat ctgtatcttt caatatttct tttgcgaatt cataccaaga acagctattt
     9781 tcgttcgaca aatgataaat accaaatggt gctttttctt cgatgacata taccataaat
     9841 tctgccaaag tacgtgtcca agttggtcgc ccaaactggt catttactac agtcagtttg
     9901 tcgcgggttt ccgctaggcg ttgcatcgtg aagacgaaat tgtgtccata gatcccgaaa
     9961 acccaagaag ttcgtatgat ataatagtct tctaaaatct cttctactgc tttttcgcct
    10021 aataatttcg tacgaccata ttcatttagt ggattcgttt ggtcgtctac ttcgtattct
    10081 acatttttgt tttttccatc gaaaacatag tctgtactga tatagacgaa ttgagcattc
    10141 acagcttttg ctgcaagtgc tacatttctt gtaccatcaa cattgatctt ctcatctaat
    10201 tcttttgctt cttcttctgc tttatctact gctgtgtaag ctgcacaatg gaaaataaca
    10261 tcaggtttta attctgtgat gtaagccatt gttttctcgg catctgtgat atccaagtct
    10321 tttgcatctg ttgaaacata ttgcagattt ttttcatcta ataaatggcg caattctgta
    10381 cctagttgcc catttcctcc agttaataaa aacatatgat tatccgctcc ttgattttta
    10441 ttttaaaaaa gagacaggcg agcgcctgcc tcacatgtgt ttttccatta atacagtgac
    10501 attttctctg tattattgtc catttttggc atatgctgct tcaacggcct ctttttcttt
    10561 tttccaccag tcttcatgtt cttcgtacca tttgatcgtg tcagccaacc catcacggaa
    10621 gttcgtaaac tcaggcttcc atcctaactc ttcccgtaat tttgtcgaat cgattgcata
    10681 acgcaagtcg tgtcctgcac ggtcgtttac atggtcgtac gcatcttttg gttgacccat
    10741 catttctaag atcaattcca tcacggtctt attatcttct tcaccgtctg caccgatcag
    10801 ataggtttcg ccaattctgc ctttcgtcaa aatcagccac actgctgaag aatgatcatt
    10861 cgtatggatc cagtcacgaa cattctttcc ttcgccatat aattttggac gaataccgct
    10921 taagatattc gttacttggc gaggaataaa tttttcaata tgctgataag gaccatagtt
    10981 gtttgaacag tttgaaatgg ttgcacgtaa gccaaaagaa cgcacccatg cttttactaa
    11041 cagatctgaa ccagcttttg tagaagaata tggacttgaa ggattatatg gtgtttccgc
    11101 agtgaatttt tctccttcgc cttccccatg tcctggcagg tcttcacgta atggaagatc
    11161 gccgtaaacc tcgtcagtag atacgtgatg atagcgtaca tcatacttgc ggcaagcttc
    11221 taaaagtgta tacgtaccaa tgatattcgt ttgtacaaat gggaaaggat cttttaatga
    11281 attatcgtta tgggattctg ccgcgtaatg aacaactgcg tccgcttctt ttactagacg
    11341 gtccactaat tctgcatctg caacatctcc tacgaccaat tctacgcgat cgctaggaag
    11401 tccagccaag ttctctttgt ttcctgcata agtcagttta tccaaaacag tgacatgcac
    11461 ttctggatga ttgtttacca cgtaatgaac gaaattagag ccgatgaatc cggcacctcc
    11521 ggtaacaatg atgtttttca taagaaaatt tctccttaat tcttagattt ctccgtaaac
    11581 aaatggattt tctgcttcaa attcttttaa tgtcggatga cggtgatctt tttccgacat
    11641 aatcgctctt gatggatcaa ttggccaatc aatcgctaaa tctggatcat caaatgcgat
    11701 gcccccatct gcttctgcat tatagtaatt atcacactta taaaggaagt tcacatttgg
    11761 tgtcaaagta acgaatccat gggcatatcc tttaggtaca agcaactgtc gatgattatg
    11821 ttcagataag ataaatccgt cccattgacc ataagtcggg ctacctttgc ggatatccac
    11881 tactacatct aaaactgctc cagtgactac ccgaatcaat tttgtctgtg cagcttctcc
    11941 tttttggaaa tgaagccccc gaaggacacc agcttcagct gatagtgaat ggttgtcttg
    12001 aacaaagtca tatttcaatc catgttctgc aaattttgct tttgaataac tttctgtgaa
    12061 gaaaccgcga tgatcgccaa agacgtccat ttctacgatt ttgacatctg ttaattttgt
    12121 atctgttact ttcatctgta aggactcctt attcagcggc caaattcaat aaatattgac
    12181 cgtattgatt ttttttcaat ggctgtgcaa gggccagcaa ttgttcctta tcgatgtagc
    12241 ccatacggta agcaatttct tccaaacaag ccacttttaa gttctgacgt ttttcaattg
    12301 tttcgataaa ggtagatgct tcaagcaatg attcatgtgt tcctgtatca agccaagcaa
    12361 atccgcgtcc cataagttct acggatagtt ttcctttatc caaatatgct ttattgacat
    12421 ccgtaatctc tagttctcca cgttctgaag gtttgatacc tttagcgata gaaattacct
    12481 cattgtcata aaaataaagg ccagttacag cgtaatttga ttttggctga gcaggctttt
    12541 cttcaatcga caaagcttgc atattctcat caaattctac tacaccaaag cgttctggat
    12601 cattgacatg atagccaaat actgtcgcgc ctgtatcttt tgaagctgct cgttgcaaca
    12661 ttttagacag accgccacca tagtaaatat tgtcccctaa taccaagcag acactatcat
    12721 ctccaataaa ttcttctcca atgataaacg cttgtgccaa tccatctgga ctttcttgta
    12781 ctgcatattc gatctgcagt cctaaatcat ttccgtttcc aaataattcc ttgaaacgtg
    12841 gtgtatcttg tggcgttgaa ataatcagaa tttctttgat tcccgccaac atcagagtag
    12901 acattggata ataaatcatt ggtttgtcat aaatcggcat caattgtttc gatgttgcct
    12961 ttgttaaagg gtacagacgt gttccgctgc ccccagcaag aatgattccc ttcatggata
    13021 tctgctctcc tttttgattt caaatttcac tttgttatta tctcatcaat tgttatattt
    13081 gtcatggaaa tattaaggat ttaaacatct tttatcaacg tttaaaccat tttcgtttga
    13141 tcaacgccgt aatcagatga acacgccaag aaattttttg ccgtaattta gaatgtgttt
    13201 caatctcact cgcgtttaaa tcatgtcttc ggtacagagt taacggttct cttaggaacc
    13261 cagtcttctt tcctcccagc aaaccaatcc acatatcatg catcggcact tctgacggga
    13321 tcggcaaaat atcgggtttt aaagaagacc ggaaagccat accagcacca atatagtgac
    13381 ttcttatcac attattaagc catccttctt tggaatttcg aaacgaaaaa tacgaatcat
    13441 ggatctcttg cagctcgctg tccacaatga ttaaatcaga aactactact agctgatccg
    13501 gattctgctc aaaatagtca gtgatctttt tcacttttgt ctccaaccaa acatcatctt
    13561 ggtctgccaa aaagattaga tctcctttcg tctgctggat cgcataacca aaattagcga
    13621 tcaatccttg acgaggcccc gaaaaaagct ggattcgctt atctttttct gcgtattcag
    13681 ttaatatatc ccatgtatca tctactgacc catcatcaga aatgactact tcatcttctg
    13741 ctgaaagctg agataaaata ctatctaact gctctcttaa atatctgcct ccattaaagg
    13801 tagctataca aaccgaacgc acgaattcac accttccaat tcttaacata tgagcgcaaa
    13861 gtcatccgcc agatatgccg gtttttgacg gtcaagaact gtttagctgt tcttaacaat
    13921 aattgtcgtc ggtgactgga taaatgcctt tgatcatatt catgataaaa tcgattttct
    13981 gcttgtaaaa tagaacggta tcgattactt gaaacttttt catagtctaa aaccgaaaga
    14041 tcatgttcca ttcgtacagg aaggatctcc acagtttttt ccaactgatc cactttccaa
    14101 aacagccaat gatccaaaaa atctaaagaa aaagcaggat taaacccgcc aatctttttt
    14161 agaaatttga cagaccaggc aacacctgaa ttgattgcca tgattcgttc agctgttggg
    14221 ccttcaactt ctactgcttg agctgtacga ttgatataac gatctgaata taggggagaa
    14281 acttgtcggc tcccagaaaa aatcatcgga actgcagcaa cacattcatc tgtaaaggtt
    14341 actttacgca atagttcaaa ataatcgtcg actagcctcg tatcctgatc cagagtgacg
    14401 agacaacgtg ttccttcatc tgcttgagac aacgcaaaat tataagccac cgctaaacca
    14461 ggattttgcg gatcatgatg ataaacgata ttttcttttt caaacagctc attttgctgc
    14521 ctttgaggac tattatcgta aataataagc tgaatttgct tttcgctaag tgctttgctt
    14581 aatggtccat aagctggaga ttgactgaat agttgctgat aaagcacaac gactactaat
    14641 atttctggtt tcatcagaaa aaacgccacc cccacttatt gaaaaatttc atcatagaag
    14701 tcaaaaacac gcgaaacagt tttgcatttc gatgcgcacc cttcccgtaa aaatggataa
    14761 ctgcataaaa gggtgtgtac aataacttgt aacctgcttt ttcaaaactc aaacacaagt
    14821 cgttgtcttc aaagtacatg aagaaacgct catcaaaccc ctttatctct ttaaatttat
    14881 caatatcagc taccataaaa ctacctgaga tcatccgtac ataactatta gcatcagtag
    14941 gcaatcctcg gcattcaaac acagccagtc gtttgtcaaa cttttttttg acccatttga
    15001 aaggcacaaa gcgcaaaacg taatcaaaaa cagccagctg ctcacggatg aggtgctgag
    15061 ttgttccatc ttcattaaga atcttaggtg ctaacatcgc acattccgga tgttctttca
    15121 ataacaagac caatgctgta actgtctctt catccactaa aatatctggg ttacaaataa
    15181 tgccatagcg agaatcgcta gctatcagat tgtgattatg tccataacca aatccggaat
    15241 tttcatcatg aaaatagata tcgatgtagg gatatttcct atactctgtt agtctttttt
    15301 tgtactcggg aagtgaattg ttgtcaaaaa ttcggatttt tactgctgtt tcatctttta
    15361 cagttgaaat aaaattatct agtgtccgaa aaattttatc actgtttgcc gtcacaatac
    15421 taataaggat cggctggttt aatttgttat tcatctatat gacggttcca tttcttcaaa
    15481 tatttctgtt ttacttgcgt acggtactct ttattcccta aaaatcgcaa tgtttttaaa
    15541 ataaactgat gtttctcatt gatcagacca atcaattcaa ataataaaat tgcagcaaac
    15601 aacatggcaa taatcaatat gatcgttccg attcttccag tataattcat gaccatagct
    15661 gtgaaagaaa acatcaaagc catcgcataa atcgtcagga cagcaccttt atgagtaaag
    15721 cctaaactga ttagtcggtg atgaagatgt tttttatctg ctgtagaaaa agaaacacgg
    15781 tttgcttttc tcctaatgat agcaaaaaac gtgtctgtta ccggcactcc catgacgatc
    15841 agcaaagaaa tcgatgaaac aaaagtcacg ttcttcagcc cttgtagtga aaggacggcc
    15901 atcataaacc ctaggaatag agctcctgta tcgcctaaat aaatctttgc cggataaaaa
    15961 ttgtaaggaa aaaaaccgat aatacttgct acaagacaga aaataacaac tggaatatac
    16021 actgtagaag catggaggaa aaaatatcca atgattccta tcgtaattaa accgatcaat
    16081 gaaatccctg ccgccagccc atccaaaccg tcaatcagat tgaccgcatt cgtgataccg
    16141 aagatccaaa aaatcgttac gggaaaacta agccagccta gttggatata tccaataaaa
    16201 ggaagcgtga aggaatcaat acgtatatct gctacaaaat aaataataag agaagcaatc
    16261 aagatcccta tacttttttg tttaggtgtc agctcatatt tatcatcgag cactcctgtg
    16321 actatgatta ctaaagaagc aatcaagatc ggtacaatat acgattgagg gataatttta
    16381 cggaataaga ataaagtcga tataacaaat gaaataaaga taggcagtcc gcccgctgaa
    16441 ggcattggaa ctttatttat tcttctttca tttggtttgt cgaccatacc tgtttgtact
    16501 gaaatgattt tgaatacagg tgttaatatc agtgataata aaattgtcag aaaaaatctt
    16561 ataaccatac taaaagaaac aagcatatgg gcacctactt taattaagag tcataattat
    16621 tataaattat atatgtcttt ttgactatct ttttatatct tctcaaatgt ccgcaaagcc
    16681 ttattttatc ggctctacgg gcattttgct tttgtggtaa acctcgcata tctaggtcta
    16741 tcttcttata ttttccctgt caatcgtggt taaaatcgtg gtaaatactt ctatgcgatt
    16801 agacgctgaa cctctgattt tgcggtatct atggacgcat gagcgtacca gttcattgtg
    16861 atactgatgt ttgaatgccc catgatatac tgtaaatctt tcgggttcat gttcttgctt
    16921 gccagccttg tgcagaatgt atggcgtagc gtatgcggtg taatatgtgg caagggattg
    16981 tccttgtggt gcttgttgta tttctttacc atacggataa ataaggcgtt ataatcaatg
    17041 gcaacttttg gattaccttt cggattgata aacacaaaac cgctgtgtcc gtctacctct
    17101 atcgacttta tctttggtcg gctgttgata acccgttgaa atgcctgtat cgtttctttg
    17161 cttaatggca cttgccttat cccgcttttc gtcttaggcg tttcaatata atagccctgt
    17221 tccttactct ttagtaactg gtggtcgata atcacaactt cattcttgaa atcaatgtcg
    17281 gctactgtca gtccgcacag ttccgagata cgaagtcctg tctttaacag tatcagcaca
    17341 tcatcataat gcttgtgata cacgttgtcc gtcttaataa atgacaataa ggcttgctcc
    17401 tgttcctctg tcaatgcgac tttctctttg gtatcatttt ctatgacttc acttagcttg
    17461 aaatcaaaag ggtttttcct cacataatca tcttgtatgg ctatgtagaa tgacgctttt
    17521 aacgagcgtt tatggttgtt aatggtattg taggaaaagc ctttgtcttt catgcgtaac
    17581 gcccattctt tagcgtcaga gggttttatc gtatcaatgc tcctagcacc taacttgtcc
    17641 tcttttaata accgcatgag ttgttcccgt tgtttctgtg tgcttttctt cacatttgtc
    17701 ctctgtgcgt tctgtttggc atagagttgg caaagcgtca ttttcttgcc tgtgctgtcg
    17761 ataccgtcct caatatcccg tcttatctgc tgttccagtt ctcgaagtga gggtttttcc
    17821 cgttttccct ttggtgtcgg gtctgtgggt gtcaatctcc aagcatacac atattttgtg
    17881 tttcccaatg cgtctacata tttatataag tattttccgt ctgttcgttg gctctctcca
    17941 gtatgcagga tacgaccttt gttatcccgt cttttttctt tcatggtgtc tgctcctttc
    18001 cttgttggaa agagccttga tatgacttgt gttcatcata acacatacaa ggctcatttg
    18061 cattagattg cgtccaattt atcaataacc ttttcaaact gtcggcgttt aatctgtatg
    18121 cggttgccat tcataatgag ccagccagcg tccttgtttt cctctgccaa tcgtcttaac
    18181 ttgttttctc caatgcggaa atactttgac gcttcttcaa tggtaagggt gtatttttcc
    18241 catacgggaa tatcctgtgt attactcata aaacaccccc tcactttcga ttacgtctga
    18301 tatgtccgta cacatctgtt ccacaagcat ttcctgtttt tcagaaaggt gggtacattc
    18361 atcaatcatt ttcatgtagt ttgaacctgt cagcctgtcg atttcctcta tcatcacgat
    18421 tgacggcatg acctgtcttt ccagccattg cagagtgcgt tccatattga caggtacagg
    18481 gttcatttca aaaggtaaac tgtcatggga aatgaatatc tcccacaatg gatagtcagg
    18541 aaattccaca aaatcggtaa tgagataaaa caccagccca tgagggttat acgtcaataa
    18601 cagttcttca actgcctgta ccgccttttt gtcacgcaga cgaatttcaa aacggttgat
    18661 aatatcggta tgtttctttt tcgttgcctg ttccttttgt ttttcataca ggcagaaata
    18721 ttttgtgctt gcctttgagc cgatataaag ggtacttgct aaattacggt tttttccgct
    18781 taattttcca ccttgtacat tttcatagtt tttacagcga cattccgcac caccatttct
    18841 gtatttttca gatagcacag gaatatccag cagaccgcac atatcattga ttgccaagtc
    18901 aaaacgtcgg ataacaccgc cacagtcaag acagcggttt aagaatgaat accagtccct
    18961 gttctgtgcc tgtaagacat attccatgtt gcgtgagcct gcccctttta attctaaaaa
    19021 tacgcccatg tgttcatcat cagaagccat gaccttgatt tccccgtaag cataatgctc
    19081 cttatagcca taatacccat agtcataatg gataaaataa tctgctttca tgccaagcac
    19141 ctttcggata acttccaatg cgtcagtcgt tggaaaacgg acagacagat aatcaacgag
    19201 cagataaaaa ggcttatcgc agatatagta attcagacaa cgcaggataa tgttctgtgt
    19261 ttccttgctg gcgttagctt ttccgttctc aaagcggttg atactatatc ttgatacatg
    19321 ggtaagactt gcaagttctc cttgtgaaag accgctggca agacgtttgt tcttcatttc
    19381 aagtgcaaat tctaaattgt tcattgtatt cctccaatcc cacaatagcc ttgaaatacc
    19441 tgtaaaccac ctttcaaaaa gtgtgatatg tactatcttc ttaaaacctc tcattactac
    19501 tcacaggttt gggggtgtat ggtttttgac ttgtcttttg tgaaatagtg cccccctgtt
    19561 agataacggg ggcacagaca aggctcgcag gctcgccagc cgacaaagca tttcttcccc
    19621 ttgacacaag gtgtcatggc ggtaagcctg agaggcttcc gccaccgtgt cagaaatact
    19681 ttgtcagcaa gttctgtttt gccttttcta acaagttcca tttcaaccga tattcatatc
    19741 tacggattta atcagatagg tatttctttt tgaatgtttt tatatttcat tctattgtgc
    19801 ttattcgatt acaagaacat agtaattctt atatgcttat ttgtcaatat ctttttttgc
    19861 ctttacaaat catattaagc atgatagact tataatagcg aagatataac gagatatgga
    19921 gggttatgca atgaaaataa gccatttagg aaataatata cagaccataa gaaaatttag
    19981 gggaatgaaa caacaggaac ttgcggacaa aatcggtatc aatatgcaga gcctttccaa
    20041 gattgaaaga gggttgaact atcctgccta tgaaacgctg gaaaagataa tggaagtgct
    20101 ggacgttacg cccaatgaat tgttgtcggg agaatggaag tatgtcaatc aatctgaaaa
    20161 ggaagtctgt cagtttttaa gagccgaaga acgtctaaat gcagaactga aacatggaca
    20221 ctatgataac ttctttgaca gcgaggaaga atggctggaa tatgagttag aaaagttacg
    20281 ggaatatatt acagactata tcaacgggaa aagcattgaa gcgtccgacc tttacccaat
    20341 caaagaattt atccagcatt tgaagtttca aaaattatta gaccgctatg atgatttata
    20401 cagtatggat atgtttgggg aaagcataga gggacataag tataagacac cttatcaagt
    20461 cgtgaaaatg ataaacccga actcaaaaga agatatggaa ctgttacgag aagtattaag
    20521 gaataacaat tttgatgatg aggacgagta acttttttcc tcttgcgaga agatacagca
    20581 aacaaaaagc ccgatcaaga gtgcaaagca ccaccaatgg tggcaaagct cttgacaggg
    20641 ctttttcttt tctgttgtgg gcaatcaaga ggaagaaagg gataaaatct gatttgtggt
    20701 aaatcaggca aaggcaacgc aggtatcaca gtatgaattg acaccgcata aggaaagcaa
    20761 ctggaagatt gtagaataaa tgaaaaaggc ttgcattctg catttttata aaattgcaag
    20821 tctttatatt gacaagcata aaatactaag atatacttta atcagaccaa cggtttgtat
    20881 tggaggtaag ttatggcacg aaataaatat ccagaagaaa cagtaaaact cattttagat
    20941 gtttctacaa aaatgttttg tgaaaaagga tatgataaca catcattgca agatattatc
    21001 aatgaaacaa aactttctaa aggtgctatt tatcatcatt tcgattcaaa ggaagatatt
    21061 ttaaaagcaa tttttcaaag aattggaaat gaaaatgcag taatatttgc taaaattaga
    21121 gataacgata gtttaaacgg tttagaaaag ttaagagaaa tatttaagac agcggtattc
    21181 aattctaacc aaagcgtttt attgacagtt tctcctcaac tattaaacaa tcctcgtttt
    21241 cttgctatgc aaatagaaca aatgtatgaa attgtagtac ctgaatttgt tgaacccgtt
    21301 ttagaacaag gtatcaagga taagtctttg gagattgaaa attcacatga aattgcagaa
    21361 gttatcatgg tattaagtaa tgtatggctc aacccattag ttgaaatgac ggataaagag
    21421 ggtatggaaa aacgttgcaa tacattcaat gcccttttaa atggaatagg catagacaca
    21481 ttattagacg aagaaacaat ttctgcattt atacagtttt gtaaataact gtatttgtta
    21541 tccctatacg atagactgct ctataaaaga gcagtttatt taaaccatta tataaaccga
    21601 cggtctgttt gattaaataa aaaggagaga ttttatgcaa gcagaaaaaa aactttttaa
    21661 tcgtgatttt atacttgttg ttataggaca gataatttct ttatttggaa acgctatcct
    21721 acgatttgca ttaccgtact atttgttaaa agaaactggt tcatcagctt tgtttggtat
    21781 tgctacagcc tgctcttttt tacctatggt tattttgtcg ctggtaggtg gtattattgc
    21841 tgacaggaca aataaaagaa acattatggt catactagat tttgtaacag caatcataat
    21901 tttagtattt tatttgtcat tgggaaaaat tcctatcata cctttgttta ttgttgcttt
    21961 gatgttactt tatggtattt ctggtgcata tcaaccagcg gtacaagcaa gtattcctct
    22021 attggtatca tcagataaac ttaccgtcgg taatgctata ataaatcaag taaatacttt
    22081 agcaaacttt atcggaccag ctataagcgg agtagttttt caattttatg gtatcaatcc
    22141 cattttaatt gttagtatta tatgttttac tttttcagcc attatggaaa tttttatcca
    22201 tattccacac caaaaaagac ctcgtgaagt aggtgtaatt gcagttgcta aaaacgattt
    22261 aaaagatagt tatacctttt tgaaaaagga gaaacccatt tttatatccg taatcttttt
    22321 ggtttgcatt ttcaatttgg ttttaagtgc tgttttaatt gttggtctgc ctatcttaat
    22381 ttctgaagtt ttaaaaatgc cagatacact atatggtttt tcacaatcag cattatcatt
    22441 aggtggttta tgtggtggta ttttaacagc tcttgttgct tcaaagttaa aactaaaaaa
    22501 cctttatacc ttgttactta tttgttctgt ttctgtttta cttatgggaa tttcgctatt
    22561 tttagaattg cctgcaatag tttcctactg ggtagttaca gtgatgtgct ttgtggctat
    22621 gggtgtatct actatgtttg ttgttcaaat ttacactctt gttcagacac aaacaccacc
    22681 gcaattagta ggaaagataa tggctacgct ggtagcagtt gctatgtgcg gtcaacctat
    22741 tggacaaatg gtttacggta ttttattcga tgtatttata caagaaacat gggttgttat
    22801 gtttgtagct tctattgctt caatcatgat ttcaatatat tcaaaaagaa tttttcaaaa
    22861 gttagagata taatacaagg ggttaaatag tatgttaggc taaaaacaat atataaaaga
    22921 aaatttgaaa tctgctaaaa ggatagtgtt ataaaagaaa gagtaatatt gcagtattta
    22981 aggctcgcac aaatatatgt tttgtgtggg cttttttctt accatttttc tgtatttcta
    23041 aagggtataa acggtattcc gtttatatat ttcagcatta gcagaaaggg ggtgagatta
    23101 tgaggacatc ttctttcgag catatcgtca gattacagtt caattcttta atgctgattg
    23161 tcattaagaa caaagtgaaa agtcgaaaca gacagcttgc aagacattct aaacgtgaag
    23221 tattgttttg tgaaatagcc gaaacgaaac aagttgaacg tggaacgatt gatacctgtt
    23281 tttatgattg tgtatcattt aaagtcttgc actttacaat ttatgtatct gatgaaacac
    23341 ttggtacagt tttacataga ctgtcagaaa aacagcgtag tgcgatttta ttacgttatt
    23401 ttcaaggaat gaacgacaga gaaatttcag aactgtacca tgtatcacgt tctgctattt
    23461 gcagtagaag aactagagga ctaaggaagt taaaaatgct tttgagcgaa aggaagtaaa
    23521 gaaatgagta aagattatgg ctatccctct tttgaattga tttgcaaagc gtcaagcgga
    23581 gatgaaatgg cagttaaaga gattttgaag ttttatgacg gttatatttc taaattatgc
    23641 ttgcgtcctt tttaccactc tgaaagtggt aaaatcatta tgcaggttga tgaagaacta
    23701 aaaggagaaa ttcatacaga catgatgaaa gcaatattga aatttgaaat cggagtgaag
    23761 taatcaactg tataaaaaaa tcgggagata cacagtttcg tgctatctcc cttagtagtt
    23821 ttacggtcat atcaaggctc attcaatcgt ggtaaattcg tggtaagatg agtgtttttc
    23881 tatacttcaa aatgcttgaa tgtatagtgt ttatgcggat aattgaaaat tagatataaa
    23941 atttcaaata aattactgat ataaatttac aataagaact cttgtttcta ctttttttta
    24001 tgagaaaatt tagttttcaa tttattgaac cattttcggc ttggatctcg acgttttttg
    24061 atttgatgac ccgtcacgta ttcttgaaca actgcattga tgattccgcc caaaatgatg
    24121 atcgtagcag caaaattaag ccaaagcatg agtacaataa aacttcctat gatctgataa
    24181 ccgctgatcc tcgttgcaaa atacctagca tagatactaa acacttgtga taacagcatc
    24241 cagccgacag tagcgaagat cgtgcccgga atgatcgtct tcaacttcaa ctgagcatta
    24301 gggacaatta aataaatcaa gaacatgatg acaaataaag ctaccaatgt gattggccac
    24361 ttcaaagttt ggaactgatc gataaagttc acgggtattt gtacgattgg ctgaatagca
    24421 tccaaaatca gctgtcccaa cccaagaacg atagttaccc cactaatagc aatcatgaac
    24481 aagacaatga caattagtga gaagaaacgg acgatcaaaa aattttttct attttctacg
    24541 ccatacgctt tattcatcgc aatttgcaaa gcattgatac tttgacttgc agaccataaa
    24601 gccgctaatg cagaaacgga taacaagcct cctgaacttt gtgtcaaaag gtctttgatt
    24661 gcaggaccga taaactggta aacggtctca ggaatcactt ctcgtaaata ggtcagtaca
    24721 gtctcttgat cgatgtggag aaacggtaaa atattaccaa aagcaataat caatggaaat
    24781 aaagacaaga gtaaataata agcaacgacg acagaggtcg tactcatttc tgaatcagtg
    24841 atgcgctttt gagtcgtctc aataaagcgc atcagatttt cattttgttt tattttgttc
    24901 caaactttca tgtacctctc ccgtacctat tgactggata gatcaataag tgccttcttc
    24961 tccttgtgat gtcaaaattc ttggaccatc tttagtaata gccaatgtat gttcatattg
    25021 gcaagaaagt ccgccgtctc ttgtatacgc agtccagccg ttaggatcca ttttcatttt
    25081 ccaagttccg gtattaacca taggttcgat cgtgataacc atgccttctt tcaaccgcaa
    25141 cccttttcca gcttctccgt aatgaggaac tgctggttct tcatgaatcg taggaccaac
    25201 gccatgacca ataaaatcac gaacgatcgc tagattttcg ccttctacat aagtttggat
    25261 agcatgaccg atgtcaccaa tccgattccc tacttgtgct tgctcaatac cgatgtacaa
    25321 agctttcttc gttacttcca tcaatcggtc gatctcaggt gtagattctc caactacata
    25381 ggcccaacaa gaatcagaaa tgccgccttt caaatcgata cacatatcga cttttaccaa
    25441 atcaccgttt ttcaaaggct ttttacgagg gaatccatga caaatttcat catttatact
    25501 gatacaagtc gcatattcat acccttcaaa gccaatttgc gcagcaattc cgccatgact
    25561 ctcgatatag tttctgacaa atacctcaat atcccaactt gtgattcctg gttttataaa
    25621 atcacgcaga tttttatgta catctgctaa taaagctcca gattctgcca tcatttcaat
    25681 ttcacgtgct gattttaaag taatcatatt ttcgtctcct ttttacaaat ccctctcatt
    25741 ttaacatagc ggcatacatt tagccaaatg acattcccca ggtgtctcta ggttttattt
    25801 tcttttcaat gatgttttgg tataattcat aattgttaaa taattataaa cgaggaggca
    25861 catcatggct ttagcaaaaa tcgtatatgc tagcatgaca ggaaaca
//
LOCUS       DAZKKZ010000233        15541 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.guided.063, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000233 DAZKKZ010000000
VERSION     DAZKKZ010000233.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15541)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15541)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15541
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.guided.063"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            367..1230
                     /locus_tag="ACG8LA_003122"
     CDS             367..1230
                     /locus_tag="ACG8LA_003122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HFQ0205311.1"
                     /translation="MLKDLNQLIDYIEEHLTEGLSYKIIAENTGISEYQLKRIFTFIA
                     GMSLMDYIKNRRLALANRDLLDGSRVTETAFRYGYETVEGFSRAFRDWSGYLPSEISR
                     YGIQKSFPRLTFFIDVRGGKSMEFRIEKKEQFYVAGVAKKVPVKFEGVNQEIQKLAQT
                     ITETQREEMHKLGDLYPNQVINVSYGFDGDRLEEKGSLMHMIGFATTKENPYADLEML
                     AIEEHTWAIFPNKGPFPQTLQDTWGKIYAEWLPSSDYGLVEAPEISFTKWGEDFSNVY
                     SEIWIAVKAKK"
     gene            1330..1812
                     /locus_tag="ACG8LA_003123"
     CDS             1330..1812
                     /locus_tag="ACG8LA_003123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HFQ0205312.1"
                     /translation="MAKYRIEEKPDFTVTGIGVELKSSNTDFVGLAAEKQAFEQKVIG
                     NGTIDALKQAAENHYFFTVNEPYNGKMMYYVGVQTSQDVPNTTRIIPFPKGTYLVVSA
                     LAESPEELRNDLTNTAFGHVLREVEDYAYVGGPNAVVEMGVTNGKYMGEIWIPVVNKP
                     "
     gene            complement(2075..2542)
                     /locus_tag="ACG8LA_003124"
     CDS             complement(2075..2542)
                     /locus_tag="ACG8LA_003124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HFQ0205313.1"
                     /translation="MKYSLQFSDAIHVLAYIEMFQDTRSLSSEMIASSIETNAANVRK
                     IMSQLKKSGLIFTKTGKPQPSLAKSPDQISLLDVYRSIEGNTQLIQVDPKTNPNCVVG
                     ANIQEALEESYARLQKKAEEEMAKITLDSLIHKIAVLEKEKRPENTGLVERFL"
     gene            2665..3516
                     /locus_tag="ACG8LA_003125"
     CDS             2665..3516
                     /locus_tag="ACG8LA_003125"
                     /EC_number="1.6.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016655 - oxidoreductase activity, acting
                     on NAD(P)H, quinone or similar compound as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HFQ0205314.1"
                     /translation="MHYLVTGATGGFGGYALEFLKKMVPQNEIYVLVRSEEKGEALKE
                     AGFNIRIGDYDDLDSMKEALKGIDRLLFVSGVPGNRQAEHKNVVKAAQAAGVSYIAYT
                     SFADADHSISVLAPDHQFTEKMIKDSGISHTFLRNNWYVENELPIIGQALKTGQFVYA
                     AGNGKTGWALKREYAEAAAKVLVESDSPEILELSGNLTDYEELAKALERATGKELEII
                     EASDAAFVENLKEAGFPQEAADMFLAIQHDIKKDQLAISSDDLEKVLGKPLTSLEAAL
                     KEILDQE"
     gene            complement(3767..5725)
                     /gene="nagE"
                     /locus_tag="ACG8LA_003126"
     CDS             complement(3767..5725)
                     /gene="nagE"
                     /locus_tag="ACG8LA_003126"
                     /EC_number="2.7.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015572 - N-acetylglucosamine
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-specific PTS transporter
                     subunit IIBC"
                     /protein_id="HFQ0205315.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAAARPAQTNTVVKTETFAGETIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVEEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(5722..6594)
                     /locus_tag="ACG8LA_003127"
     CDS             complement(5722..6594)
                     /locus_tag="ACG8LA_003127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HFQ0205316.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            complement(6936..7808)
                     /locus_tag="ACG8LA_003128"
     CDS             complement(6936..7808)
                     /locus_tag="ACG8LA_003128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFQ0205317.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKIFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            7936..8505
                     /locus_tag="ACG8LA_003129"
     CDS             7936..8505
                     /locus_tag="ACG8LA_003129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DapH/DapD/GlmU-related protein"
                     /protein_id="HFQ0205318.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLLVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            8572..9309
                     /locus_tag="ACG8LA_003130"
     CDS             8572..9309
                     /locus_tag="ACG8LA_003130"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HFQ0205319.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            9540..10808
                     /locus_tag="ACG8LA_003131"
     CDS             9540..10808
                     /locus_tag="ACG8LA_003131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HFQ0205320.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            11295..11759
                     /locus_tag="ACG8LA_003132"
     CDS             11295..11759
                     /locus_tag="ACG8LA_003132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HFQ0205321.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIEH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            11743..12372
                     /locus_tag="ACG8LA_003133"
     CDS             11743..12372
                     /locus_tag="ACG8LA_003133"
                     /EC_number="1.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0016657 - obsolete oxidoreductase
                     activity, acting on NAD(P)H, nitrogenous group as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HFQ0205322.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMQPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGVEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITTFE"
     gene            12726..14204
                     /gene="msr(C)"
                     /locus_tag="ACG8LA_003134"
     CDS             12726..14204
                     /gene="msr(C)"
                     /locus_tag="ACG8LA_003134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HFQ0205323.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRPDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            14251..14697
                     /locus_tag="ACG8LA_003135"
     CDS             14251..14697
                     /locus_tag="ACG8LA_003135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HFQ0205324.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(14896..15411)
                     /locus_tag="ACG8LA_003136"
     CDS             complement(14896..15411)
                     /locus_tag="ACG8LA_003136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HFQ0205325.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
BASE COUNT         4988 a         2781 c         3186 g         4586 t
ORIGIN      
        1 tgatgaggtt gaacttttac acaagattgt ggacttgact gcaaagaaaa atccaagcag
       61 cgttctgatc agcagtttga acaacaattt gctttgtaca gtaggtagta agcggattaa
      121 ctaagggaat aaaagatatt tttaccgctt tgtttactta gaatctgtct tccccaaaat
      181 ttatttttct aaaggtaaaa catagatagg cagataatac caattatccg ttacgaaacg
      241 ctgcttgaga attttcttta gatccataca acattttcta catctgacta aattggttcc
      301 tgattcatca agtaattgac tttctttgat aatatgataa aaaggcaatc aaggaggaag
      361 ataaatatgc ttaaagatct gaaccaattg atcgattaca tcgaagaaca tttgacagaa
      421 ggactttcct ataaaataat agccgaaaat acaggaatct ctgaatatca attaaaacgc
      481 atctttacgt ttattgcagg gatgtcgcta atggactata tcaaaaaccg tagattggct
      541 ttggctaatc gcgatcttct agatggatca agagtgacag aaacggcgtt tagatatgga
      601 tatgaaacag tcgaaggttt ttcaagagct tttcgtgatt ggtcaggata tctgccttca
      661 gaaatcagca gatacggcat acaaaaatct tttccacgct tgacattttt tattgatgtc
      721 agaggaggaa aatcgatgga atttcgtatc gaaaagaaag aacagtttta tgtggcaggt
      781 gtggcgaaaa aagttcctgt caaatttgaa ggagtcaatc aagaaataca aaagttagcg
      841 cagacgatca cggagactca aagggaagag atgcataagt taggagattt atatccaaat
      901 caagtaatca acgtttctta tggatttgat ggagaccgct tggaagaaaa gggcagtttg
      961 atgcacatga ttggctttgc tacgacaaaa gaaaatccgt acgctgattt agaaatgctt
     1021 gctatagaag aacacacttg ggccattttt cctaataaag ggccatttcc ccaaacttta
     1081 caagatactt gggggaaaat ctatgcagaa tggcttcctt cttcagatta tgggttagtc
     1141 gaagctcccg agatctcttt tacaaaatgg ggagaggatt tcagtaatgt ttacagtgag
     1201 atttggattg cagtgaaagc aaaaaaatag ttaaaaaata aaaatatccc tagaaaaaag
     1261 agcgtaatcg tgtcatttcc ctttaatttt atgtaagatg aacttaatat aatagaaagg
     1321 gtgggagaaa tggcaaagta taggatcgaa gaaaaaccag attttacggt gacgggtatt
     1381 ggtgtggaat tgaagagtag caatacggat tttgtcggtt tggctgcaga gaaacaagca
     1441 tttgagcaaa aagttatcgg taatggaaca atagatgcat tgaaacaagc tgctgaaaat
     1501 cattatttct ttacagtcaa cgaaccctat aacgggaaaa tgatgtacta tgtcggtgtt
     1561 caaacgagtc aggatgttcc aaacactacg cgaatcatcc cattcccaaa aggaacgtat
     1621 cttgttgtaa gcgctttagc agaatcgcct gaagaattaa gaaatgattt gacgaatacg
     1681 gcctttgggc atgttttaag agaagtagaa gattacgcct atgttggggg tccaaatgct
     1741 gtagtcgaaa tgggagttac caacgggaaa tatatgggag aaatctggat accggtagtc
     1801 aataaaccat gataatatag aggtcgtgaa agtagcgctt tgacctgagc attagagagg
     1861 aaaaatggga aatagctttc catattttgc atttttcaga actaatgccg agggtcagct
     1921 acttgaacac cgtttatcaa gacgtcatga cttcagcgct ttgacctgag cattagagag
     1981 gaaaaagggg catgacaagg cttttgtccc ccggagaata aaagaattta tgtagacgat
     2041 tccgatcaga aaaatgcagg cacagtagag agaattataa aaatctctct acgaggcctg
     2101 tgttttctgg tcttttttct ttttccaaaa cggctatttt atgtatcaga ctatcaagtg
     2161 tgatcttagc catttcttct tctgcctttt tctgcagccg agcgtagctt tcttctaaag
     2221 cttcttggat attcgcacca acgacgcaat ttggatttgt ttttggatcg acttggataa
     2281 gctgtgtatt accttcgatg ctgcgataga catctagtaa agaaatctga tctggacttt
     2341 tggcaaggga aggctgcggt tttccggttt ttgtaaagat caaaccggat tttttgagct
     2401 gactcatgat tttacgtaca tttgctgcat ttgtttcgat actactggca atcatctcac
     2461 tagaaagtga tcgggtatct tgaaacattt caatataggc aagtacatgg attgcatcac
     2521 taaattgcag agaatacttc atcagttgtc atcctttcat tttttttgct tgacttatct
     2581 taccacactc tttatgataa aggtgtaatt tataaatgta cagctgtaaa tcttaacaaa
     2641 taaaaagaat agggagtggc aaatatgcat tatttagtaa caggagcaac tggaggtttt
     2701 ggtggttatg cgctggaatt cttaaaaaag atggttccac aaaatgaaat ctatgtacta
     2761 gtacgtagtg aagaaaaagg agaagcactg aaagaagctg gatttaatat acgtattggt
     2821 gattatgatg atttagactc aatgaaagaa gcgttgaaag gaatagatcg attgcttttt
     2881 gtctctggcg ttccaggaaa tcgtcaagcc gaacataaga atgtagtgaa ggcagcacaa
     2941 gcagctgggg tatcttatat cgcttataca agttttgcag atgccgatca ctcgatcagt
     3001 gtattagcgc cagatcacca attcactgaa aaaatgatta aggattcagg tatttcccat
     3061 acatttttac ggaataattg gtatgtagag aatgaattac ctatcattgg gcaggcttta
     3121 aaaactggtc aattcgttta tgctgcagga aatggaaaaa caggttgggc attgaaacgt
     3181 gaatatgcag aagctgcagc aaaagtacta gtagaaagtg actctccaga aatcttagaa
     3241 ttatccggca atctaactga ctatgaagaa ttagccaagg cattagagcg tgcgacaggt
     3301 aaagagttag aaattattga agcaagtgat gcagcgtttg tcgaaaatct aaaagaagcc
     3361 ggattccctc aagaagcagc tgacatgttt ttagcgatcc aacatgatat taaaaaggat
     3421 cagttagcta tttcctctga tgatttagaa aaagtattgg gaaaaccatt aacttctctt
     3481 gaagcagcat taaaagaaat attggatcag gaataatgta taaagaggtt gtgaaaaagc
     3541 cgattagttt tgagtatgaa gaaaaatttt gtgaaaaagc tgttctgcat caagtaataa
     3601 gaagagtcaa ataaaaaata gctcttcata tgtttcgttt agctggactt attaccgcgg
     3661 agttggcagg agaacgccgt ttttattcgg aaaaaggagc tgagacaaga tttttgtctc
     3721 agctcctgtt tgtttatcga taaaaaagtc tggggaagac gatggctcag gctttgttgg
     3781 aaacagagcc gattttatca tttgctttta catcacgtgc gggttcgatt tctaagcttt
     3841 ggactttgtc gccatttgtg aatacaacga ccatatccgt gtttttgcct gcagattgaa
     3901 tagcggcaag atcaactaaa gcaatcaatt gacctcttgc gactttttga ccttcttcta
     3961 catataaagt gaatggttcg ccttttaagt caacagtgtt gatgcccata tgaagcaaga
     4021 cttcgatacc agcatctgtt tggattccga cagcatgttt cgttgggaaa atgtttgtga
     4081 tcgtaccagc gattggagag aagatttctc cattttctgg taatacagca tagccgtcac
     4141 ccatcatttt ttccgcgaat acatcatctg aaacttcagt gattggaatc agtttcccat
     4201 ttgcgatagc gtaaatatct tgttcgatcg tttcaccggc aaatgtttct gttttaacca
     4261 cggtgtttgt ttgtgcaggt cgtgctgcag caccaccatg tagttttgcc atctcatctg
     4321 caacgaattg tacttctgta cctacgatga cttgcgcatt ttttccgtcg atgatcttca
     4381 taccaggtac gccagtggct ttgattttat tttgatcgat caggcctgta tctttgactt
     4441 gcaaacgaag gcgtgtagta cagttatcga tcgaagttac attgtcggct ccgcctaatg
     4501 cagcgtagat tttgcttgct tgtgccgcat atttattgtc tgaattagtc gttgcagtat
     4561 cgtcatctga aagatctgct tcctcgcggc caggagtcat cagatggaat tttttgatag
     4621 caaagttaaa gccaaagtag taaatcactg ctgttactaa tccttggacg atcaacatca
     4681 atggctgatt cgcaatcgga tttttcaaag ataggaagta atcgacaaat ccggcactaa
     4741 aggcaaatcc tgctgtccaa tggaagaatg cactcactgc taaagaaatc ccagtgaaaa
     4801 ttgcatgcaa gacatataat ggccaagcaa cgaacataaa tgaaaattca agtggttctg
     4861 tcacaccagt aaagaatgaa gcaaaagctg ctgctagcat caaggaagct gtttttgctt
     4921 tgttttctgg acgtgcattt ctgtaaatag catatgctcc tgctggaagc ccgaacatca
     4981 tgattgggaa aaatccagct tgatacattc ctgttacgcc ttttgttcct tcagaagcca
     5041 aaaatttacc aatatcattg attcctgcta cgtcaaacca gaacacggag ttcattgctt
     5101 gatgcaatcc tgtagggatc agtaaacggt tgaagaagcc ataaagacct gcaccacccc
     5161 agcctaaact caaaatgaat ttagcaaaag aaactaaagc agagtaaacc ggaggccata
     5221 cgagcagtag cactgcactg atcagcaaca tgacaaaggc agccaagatt ggcactagac
     5281 gcttgccgct aaagaaagat aaagccatcg gtaattttgc ttcgtggaaa cgattataaa
     5341 gagctgccgc aatcaatccg gcaataatac caataaatac gttactgatc tgagcaaaag
     5401 atggatcaac tgattctggt ttgatattca ataaagtagc tactgaatca gtttttaaaa
     5461 catttactgg aacttcaaat gcgaccaaac ctgccaaggc agcagcacct gatttgtcca
     5521 ctgacatccc tagtgctaac ccaacggcaa acagcaaagg taattgacct aaaactgcgt
     5581 taccgccagc ttgtaaaaaa tgagcgacaa tgtcgttact ataagatgcc caccagtttc
     5641 cgatccctac tagtaaagca gcagcaggta agaccgcaac tggaagttga agggaacgtc
     5701 ccattcgttg tagatatgct ttcaattttt ttcctcctca tgattgttaa catttgtttg
     5761 tacgattgcg cttcttaaac gctcgatatg gatggccaag taacccagtt cttctttcgt
     5821 gatcgcgagc tggtattctt tggtcagcaa cacacggatt tttttagaaa tcttatagct
     5881 ttctgggtat tttcgtttga ccatttctac gatttccgtg tctaaaacag catattgttg
     5941 cgcatgggtt cgttgtagaa gcagtcgtaa atgattcacc agtcttgaat aattcagtga
     6001 aaatggttct gaatggatat ctgtttccaa ttctgattcc actaaatgga tgatgtcaga
     6061 tacaatcgtc acttcacgga tactgcgatg gttattgttc cgaccgcttc gtccgctgtg
     6121 aatatggatt gcgatatatc ctgcttcgtc ataagtatat ggaatcccaa gctcttttgt
     6181 cagatactct actgcccatt gagcaatact gaattcatca ctgtaaagca cttcgatttc
     6241 tcttaaaagt ttgttgcgga tgacgatacc gttattaatg ttctccgcag aaaaagcaat
     6301 gtggtcggtc aaagcgatca atacatgttc attcaacttt tccatcaaaa cagtttccgc
     6361 atgatcaatg atcgtttctg ctgcaaataa aaagcgttca tcaatctgat taagtaaatt
     6421 ttgcaacttg atttgacctt ctggttccat gacaaatatc cgttcgacat cacgatcaaa
     6481 aatcaaatca tttctttttc tgtcaaatcc aatccctttt ccaatagcta ctttttcctg
     6541 tccaccgtca tctaccaata ctgcattttg attaaagatc tttttgattt tcatgcgcgc
     6601 accctttttg aagatttggt tttcacgttt gctagaccag ttgattgcgg ccaaacaaaa
     6661 atagacacga aaaacctcct agggaaacca tgttcctcag agatttttca tgcctagtat
     6721 gatctagtca catgaaacga attattgtta acgtaatcaa ttttatatag acagttatgt
     6781 tttgtcaatt ctttttttat aattatagta atttactgga attatcagaa ataaaaggaa
     6841 gaaataaatt aagaaactta tgttatttaa tcgttggatc ttttgcttat cttattcgtt
     6901 gttaaaaagc tgaaagcgaa ggaaaaaaac tctacttaac tgtatttctc cgttaggaca
     6961 tctaaaaatt tacgagcagc aggagaaaga ggctggtctt ttttccaaat gagattcagt
     7021 gaagcttgta atggcggatc gagtgggatg aatatttttt ccgtcccata agtattgatg
     7081 atcccatcta gagctaatgc accaaaagtc ccgttatcga ccatcaaaga agcattgtac
     7141 aataagttat atgttccgac gatcgataac tgatctatgc tgaaacctag ccattcagct
     7201 agttgactgt ccactgacgt ttgccgggaa atgatcaaag gaacagtttt cagttcctgc
     7261 ggatggatga cggtttgctt tgctaaagga tgatttcgat gtatcaaaag tccccaacga
     7321 tcttgggctg gcagtcgaaa tgactggtat ttttgtttgt ttgtcggttc gattacgagt
     7381 ccaaaatcaa gtaatccgct atccagtttg tctatgatat catctgcatt cccgctatat
     7441 aaatgaaact ggatatcagg atgcgccttg atcaacgaat gaaggctatc agaaatgaaa
     7501 gagattgctt tagtttcgcc tccgccaatg tagatttctc cagagatgat tgcgtcattt
     7561 gttaaattgt tcgccgtttt ttctaccaac gacaagattt cttttccttt tgaataaaga
     7621 tatcgaccag aatccgtcaa ctgtatctct cgggagcccc gagtgaaaag tgtcacacca
     7681 agttcttctt ctaaatcttt cagttgtttt gagagagtag gttgcgtgat atgcagagat
     7741 tttgctgctc ggctgatatt tttttctcta gctactgcta aaaaatacgt cagtatacga
     7801 atatccattt tttccctcct gtttttaaaa aagcatacca ctaagtatag ttaaaaggaa
     7861 tagttaagta tgttttataa gtattagaca tgataagccg tccgttataa agtaaggata
     7921 aaaggaggga gcaaaatgac aagcctcatc gaaaaacaaa tcgtcaataa agagattcga
     7981 gtaacggatc cgctctttga agtgatccat cagatccaag ctgaaaacga agagccttta
     8041 gcagcgctga atactgggta ccatgaacca gcagatatcc gcaaacggct agaaaatatc
     8101 attagtgaca aagtagatga tacggtgact gttctgctgc ctttttatac agatttcggc
     8161 aaacatatta gtatagggaa aaatgtcttt atcaatcgtc aagtgatgtt cgttgactta
     8221 ggtggcatct gtttagaaga ttcagtattg attggtcctc gtgtcaacct catcacggtg
     8281 aaccatctaa ccgatccaaa agaacgaaga ggcttgttag taaagccaat ccacatcaag
     8341 aaaaatgctt ggatcggagc aggagcaact attctgccag gcgtaacgat tggcgagaat
     8401 gccattgttg cagcgaatgc aactgttacg aaagatgtcc cagacaatac catcgttgca
     8461 ggaatccctg ccaaaatcgt caaacctgtc gaacggatta tttgaacagt aagatgaaat
     8521 aagagatagt gagtataagc aagagatttt tcaaaacagg aggagaatag aatgaatgat
     8581 ttatcagaaa aagtgattgt catcatgggc gcttcaagcg gaatcggtga agcaacaacg
     8641 aagctattag cagaaaaagg ggctaaacta gttatagctg cacgccgaga agatcgccta
     8701 aaagcaataa aagaatcttt accagaagct gagctatata ttcaaacagc agatgtaaga
     8761 gattttgcac aagtccaagc agttatcgat ttagcgatgg aaaagttcgg tcgaatcgat
     8821 gtattgtaca ataatgcagg aatcatgcca accgctccat tagttgaagg tcaccgtgat
     8881 gaatggcaaa atatgcttga tatcaacatc atgggtgtgt taaatggaat ttccgccgta
     8941 cttccaatca tggaaaaaca aaaatctggg catatcattt caactgattc tgtggcggga
     9001 catgttgttt atcctgattc cgccgtttat tgcggaacaa aatttgctgt ccgtgcaatc
     9061 atggaaggat tacgtcaaga gcaacggcaa aataacatca aatctacgat catctctcca
     9121 ggagctgttc aaactgaatt atatcaaacc atcagcgaca aaaaggctgc tcttgaactt
     9181 catgaagcgc aaaaagaatg gggattgacc tccgaagata tagcttctgc tgtagcattt
     9241 gcgatagaaa cgccagaccg gatgtctgtc agtaacatga ttatccgtcc gacgacacag
     9301 gaagtataat ccataacgga taatatccaa agagaattac ttgttaaata gttattcaaa
     9361 cgaccatcaa tttaaggcgt gaatggagaa gaatattctt catttacgtc tttttatgta
     9421 gaaaaagcaa atttatcaaa aagaaacaaa tgttatttaa atatggacat tgacttgctt
     9481 ttactttttt agttacactg ttatttagga aaagtttcat aattcaaagg agaaaaaaga
     9541 tgaaagcaaa gaatttatta tttagcgtta ttcttttagg aaatctagca gttgccaaca
     9601 caacagtgct agctgaagaa tcgacagaaa ctgtcgcaac tcagacatcg agttcttcag
     9661 aaacaggaat tgaaaacgat acagagagta ctttgcagtc agctactgtc tcagaaaata
     9721 caatttcaac cgaagaacca acaactgaaa caacagaaca aacacaaacc gaagacagta
     9781 catcagcaga agctcagaac aatccagaga atgcagaaga aatcacgaac caattgacag
     9841 atgggcaaac attgacacat acccatcaag cagatttgtc tgaattcgaa aactatactg
     9901 gctatgcttt ttatgctcgc tcatctgcta attctcaaca agcgttcatt gatagtattg
     9961 cctcaactgc acaaagtttg gcaagtgcca atgacttata tgcatcagtc atgattgctc
    10021 aagccatcgt tgaaagtggc tgggggaaca gtactttggc ttctgcccct aattacaatc
    10081 tatttgggat taaaggaagc tataatggcc aatctgttac gatgcctact tcggaatatg
    10141 tgaatgggca atggattacg gtgaatgccg cttttagaaa atatccttcg tacaaagaat
    10201 cattgcaaga taacgtaacg gtattgaaga cgacttcttt tcagccaggc gtttactact
    10261 attccggtgc atggaaaagc aatacgaact cttacaaaga tgctacggct tggctaacag
    10321 gtcgttatgc cactgcgcct aattatggtt ctacattgaa caatgtaatc gaaacctata
    10381 atctgacaca gtatgataca gcaccaactt caacttctcc gatgtatcgt ctgtataacc
    10441 gtcatacagg agaacattta tatacattga atgccggaga aaaaaattat ctgccaactg
    10501 taggctggga atatgaaggg attgcttggc aagcaccaaa cagcggacaa cctgtctacc
    10561 gtttatacaa tccttacagt ggagaccatc attacacaat ggcacaatct gagatcaact
    10621 ctttaacaaa aatcggttgg cgttatgaag gtctaagttt ttattctggt ggttccaagc
    10681 caatttatcg actatttaat ccaaatgaaa aaactggtac ccatcactat accttgagtg
    10741 ctaaggaaag agattggcta acaccgatgg gctggagata tgaaggaata ggattttatg
    10801 gttattaaaa agaggtagtg aaaaagctgc cctgcatcaa gtagtaagaa cagccaaaca
    10861 aaaacagatt ttcatgtttt ttgtttggtt gaacttatta ccgcagatgc aagtttttga
    10921 acaccgttta ctcaaaaaag gttgtgacaa catcttgtca taactttttt attactgttt
    10981 aagcatactg atccaatttc taatattcga cgggattctt gcaaaaggcg atttcggaaa
    11041 tttttggcgg tgtaaaattt tctactgcag aagagctatc ttctatagtt tgataagaat
    11101 caataatctt ggttttagcg ttgtgctttc tttatcattt tttccgttca ttctacaaaa
    11161 aatttctttt ctctatactt ttctattgag agcgtttttt ttattacaca gctgattctt
    11221 tgactttttt ctttttttat tctattattg acaagtcaat cgttgacgag tcaattatta
    11281 gaaaggagga aattatgtct ttagaagaga ttagtcacct tttatatcaa atcaaattag
    11341 ccgatcaaaa aatcgtccag atctttgaag aaaatatcgg tataagtctt actagatacg
    11401 agatcatgat gagactgaaa gaagaaaatc cattgctaca aagcagtttg caagaaaagt
    11461 tgcagattga tcaaggagca gttactcgtc atctgaaggt attggaagca aatggctatg
    11521 tttcgcgtca gagaaatcct cagaacaacc gggaagtgta tgtagcgcta acagaaaaag
    11581 cccagaagaa aatcgagcat tgtgaaatgg accataaaga tacaggttcc gtgctatccc
    11641 cggctttcag cgatgtagaa atgaaacaat ttctaacact tttagataaa ttgaataccc
    11701 aactttgcaa tataacaaca gaaacgaaag aggttaataa taatggaaca aaaaaatgat
    11761 ttttcaacaa ttatgactgg tagaagatcc gttcgcgtat atgatgaaac atacaaaatc
    11821 ccacacgaag aaatgctgga aatgatcaaa gaagcgacga ctgcaccttc ttctgtcaat
    11881 atgcaaccat ggcgctttgt ggtcgctgaa agcgaggaag caaaagaaat cttgcgtcct
    11941 ttgatccgtt tcaatacgag acaaaatgat acttcttctg caatggtcat gatttttggc
    12001 gatatgcaat gttacgaata tggcgaagaa atctataacc aagcttacga atcagggaag
    12061 atgccaaaag aagtcagaga tcaacaatta gctgcgatca ttccttatta caagagtttt
    12121 tcaagagaag aaatgaacga tgtagtcaaa gtcgattcta gcttagcggc tatgcaattc
    12181 atgttagttg cgcgtgatca tggctatgaa acaaatccaa ttggtggagt cgaagcagat
    12241 cagttggcag aggcatttgg tttggataaa gaccgttatg ttccagttat tattttatca
    12301 ataggaaaag cggtagaaga aggttacgag tctgttcgtt tagcaccaga aaagatcact
    12361 acgttcgaat aaaaggtttt cagttactat tcagtagcta ttgctttttt tgaatcgtgt
    12421 gtggtaacct aataaaaaag gaggtcggaa aaatgactgc atcgatgaaa ttacgtttcg
    12481 aacttttgaa taacaactaa ataaattcaa aagacatgta taaacaacaa tttcatggat
    12541 ggagtatgtc cattttttcg aacgacagta gaataggtga aagctatgac agatttggtg
    12601 atttagtcat agttatttcg ttcagagtag gaaaagatgt gatgcagttt ttttgcaaac
    12661 agatttttct gctctttttt agtatcgata attgttgttt tacatgaaat aggagtgtaa
    12721 aacatatgga aaatttagca gtaaatataa caaatctaca agtcagcttt ggcaaccagc
    12781 tagaactatc tattgattct cttcgtgtct atcagcaaga tcgtataggg atcataggag
    12841 aaaatggtgt cggtaaatcg actttgctca aactaatagc cggtgaactt tttcccgatc
    12901 atgggaaaat ccaaacagag atcaccttca actacctgcc tcaattaacc tatctcgctg
    12961 aagcaaagga cctaaatttg gaattagcca gtcatttcca gttaagactg gaagaaactt
    13021 cagagcggaa atggagcgga ggggaagaac gaaagatcga gttgatacgt cttctttctt
    13081 cttatgaaca agggatgctt ctagacgagc caacaaccca tctagataga aaaagtattg
    13141 atcgactgat tgaagagctt cgttattatt atggtacgct ggtttttgtt agtcatgatc
    13201 gctattttct agatgagcta gcatcgaaaa tctgggaagt aaaagacgga gaaatccgag
    13261 agttttcggg gaattatagt gcctatctca ctcaaaagga attggagaaa aagactcagc
    13321 tacgagaagc agagtcgatc atgaaagaga aaaaacgatt ggaaaaatcg atccaagaaa
    13381 agaaaaaaca agcggaaaag ttggaaaaag tgtccagtaa aaagaaaaag caacaaatca
    13441 gaccggatcg gttgtcttcc tctaaacaaa aagacagtgt acaaaaagcc atccaaaaga
    13501 atgcgaaaac attagagaga agactccaaa aaataggaga aacaaccaag ccgcagcaga
    13561 tgaaacaaat ccgttttcca gtaccaaaat ctcttgaact ccacagccgc tatcccatca
    13621 tgggacaaaa tgtccaattg gaaagaagtg ggagaacatt actggtaaat ggtgattttc
    13681 agttttcttt aggtaaaaaa atcgcgattg tcggtgaaaa tggttcaggt aagacaacct
    13741 tattagaaca tatccgcaaa caaggagaag gaatccttct ctctccgaaa gtaagctttc
    13801 aagtatatca gcaaaagggt tatcaaatga catctgaaga atccatcatt cgttttgtca
    13861 tgagacaaac agagttttca gaatcgcttg tccgtagttt gctgaatcac ttagggtttg
    13921 ctcaggaaac tttgacgaaa ccgttatgta cattaagtgg gggagaagcg acccgtctga
    13981 cgattgcttt gctttttact aagccaagta atgtgttgct gttagatgaa ccgactaatt
    14041 ttattgatat ggcaacgatc gaagctttag agaagctaat gcaaatatat ccgggaacga
    14101 ttttgtttac ttctcatgat tcttactttg tcgagcgtac ggctgatgaa gtttatgaaa
    14161 taaaagggca gaaaataaaa aaagtactta cgagaaattt ttaaatgtgc tacgatgatt
    14221 ttcgtgacaa atttaaagga gtggtacaga ttgcctacaa ataaaaaaga aggaataatt
    14281 tttacaacaa tgatgtgttt tttgatggtc ttggggatga gcgcgtataa tttatggctg
    14341 catcaagatc ttcatttatc aagtttgttg attggtctag tgcctggatt cgtggtggct
    14401 ttcattttgg atgtcttcat catcggtgtg ctggcgaaaa aaattgcctt taaactacca
    14461 gtaaatccag aaagcaaggt ccaaatgatc ttaactattt catgcttgat ggttttagga
    14521 atggtgacat gtatgtcttt attcggtgtg atcatggaac aaggaatacc tgatcaatta
    14581 ttctctgctt atatgaatgc ttggaaaatg aatgtgattg ccgctttacc gttgcagttg
    14641 atcatcgttg gcccgctttc aagaagtgtg ctaaaagcaa ttcaaagtaa tgaatgatgg
    14701 aacactgtta tttgaaaaaa ggccttggca tgctttttgt catagtctct tgaatgcagt
    14761 tctagaaaaa tagtgatccg aacgataggt tttggcctgt cgttcggatc gctttttctt
    14821 ttccaactgt attgctcttt tattgaagat aatttgctct tcaatagata tttctagaaa
    14881 ggttctgttt atcccttact caaaaaactg ctgcatttgt tctcttactt gctgacacca
    14941 ttggagttcc tgctgacaaa gcataattct gcgctggatc acaacataac gtccaaattc
    15001 ttgtttcttg tctagcgaga ggtcattcaa ttttttttga tttttttgca tgattttgtt
    15061 cagctgttgt tctctagtga atagcagtcc agtagctgtt gttttatcga gcgtcgaaaa
    15121 agcatagatt tttgctagaa attcatcttt ttgcgtagga gcgggagttt cctctttgat
    15181 ccattcctct acaagagcac gtccttcatc agtcaagtgg tagatctttt tttgagagtg
    15241 ctcgtctttg tccaaaacgg tcacataacc ctgctggtct aacttggcaa gcgttgtata
    15301 gatctgactg tgatgggctt cccaaaaaat tgtgatcagc tgcttcaatt catacccaga
    15361 acgtggtttg gataaaagca cgcataataa tatataggct aaagtattca taaaaatcct
    15421 acctctcgtc ttattttctt tattatatca cagtaaagtt tccacgtttt acatgtgcat
    15481 atttacatgt aaaataaatc atgtatgatg ctaatagaga gaaagggatg gaaatattgg
    15541 a
//
LOCUS       DAZKKZ010000234         7959 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.guided.095, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000234 DAZKKZ010000000
VERSION     DAZKKZ010000234.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7959)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7959)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7959
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.guided.095"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            128..1564
                     /locus_tag="ACG8LA_003137"
     CDS             128..1564
                     /locus_tag="ACG8LA_003137"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFQ0205326.1"
                     /translation="MEHKELTSFPKDFLWGSASAAYQVEGAWQEDGKGESVWDRFVRI
                     PGKTFKGTNGDLAVDHYHRYKEDIALMKEQGLKAYRFSVAWTRIFPNGRGEVNQAGLA
                     FYERLIDELIENDIEPMLTLYHWDLPQALQDEYNGWESRQIIEDFTHYAETLFEAFRG
                     KVHYWISLNEQNIFTSLGYLLAAHPPGVTDPKRMYEVNHIANLANASVINKFHELEMP
                     GKIGPSFAYTPNYPIDSNPENVLAAENAEDLMANYWMDVYMWGKYPIAAMRFLEEKGW
                     APTIEAGDAELLESAKPDFLGINYYQTATNAFNPLNGVGAGKMNTTGKKGSSEETGVP
                     GMYKKVENPFVERTNWDWEIDPEGLRIGLRRITSRYRMPVLITENGLGEYDKLTEDKQ
                     IHDDYRINYLQSHVKAIKEAISDGAEVLGYCTWSYTDLLSWLNGYQKRYGFVYVDQDE
                     TQEGSLERYKKDSYYWYQKLIEENGENL"
     gene            1753..4200
                     /locus_tag="ACG8LA_003138"
     CDS             1753..4200
                     /locus_tag="ACG8LA_003138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HFQ0205327.1"
                     /translation="MAQKKRPTKKRKKTKKTKKQKQQQEQMLTIGVGFALILFAVFGF
                     LKLGFLGILIANGFRIIAGNTYQILCLLLAVLGFWIVIKNTEFSIGKNRRWFGGILFY
                     FGILLLLHAHLFGKLHTGEPNIMGTTWDLLASDIKQSQVDNNVGGGMIGAILYHFTYF
                     LIAQPGSYLAAVLLLAGGAFLFSNLEGYQLLNGIQSIGERVQELLEGDPAKQARKQAA
                     KEERMKQRAEAKEARRLAAKEAAEKEAAEYEKKKAVSQQRENTADEWQEPENTEPEQL
                     SFVPIDSFQENIHPANLEKPVPDTPKQTNTAEGFSDELPEDDGTSLEFEIEAEQENQD
                     YELPTVDLLDSIPTVDQSDEYKKIEKNIGVLEQTFQSFGVDAKVVKASLGPSVTKFEV
                     QPAVGVKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNGKISMVSFREIIE
                     AQPNHPDKLLEVPLGRDVSGRVQTADLSKMPHLLVAGSTGSGKSVAINGIITSILMRA
                     KPHEVKLMMIDPKMVELNMYNGIPHLLTPVVTNPRKAAQALQKVVQEMEERYEKFAAT
                     GVRNISGYNEFVQQKNLENGTKHPTLPFIVVIVDELADLMMVASNEVEDAIIRLAQMA
                     RAAGIHMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDSNGAEKLLGRGD
                     MLFLPMGENKPIRVQGAFISDHEVERVVQFVTDQQEAHYEEKMMPTDEVETTGAPEQP
                     QDELFEEAKALVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVVGPSEGSKPRKV
                     FIEQEETSETLPDDNDM"
     gene            4430..5497
                     /gene="rlmN"
                     /locus_tag="ACG8LA_003139"
     CDS             4430..5497
                     /gene="rlmN"
                     /locus_tag="ACG8LA_003139"
                     /EC_number="2.1.1.192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:0016433 - rRNA (adenine) methyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0030488 - tRNA methylation [Evidence IEA];
                     GO_process: GO:0070475 - rRNA base methylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HFQ0205328.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            5487..5693
                     /locus_tag="ACG8LA_003140"
     CDS             5487..5693
                     /locus_tag="ACG8LA_003140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0205329.1"
                     /translation="MPNNRILLVFSITIKGAVFLIKELFNLNKRKDSIAKAIKLFLTR
                     KTLIKQRNVLNLMTACLMGVLAII"
     gene            complement(5690..6793)
                     /locus_tag="ACG8LA_003141"
     CDS             complement(5690..6793)
                     /locus_tag="ACG8LA_003141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HFQ0205330.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
     gene            7346..7894
                     /gene="aac(6')"
                     /locus_tag="ACG8LA_003142"
     CDS             7346..7894
                     /gene="aac(6')"
                     /locus_tag="ACG8LA_003142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HFQ0205331.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
BASE COUNT         2664 a         1359 c         1729 g         2207 t
ORIGIN      
        1 tttcttacta ctcgaaacta agcgactttt tcacaacctc ctttacatat ttttattttg
       61 ttgtggaagg ggtttcgtgt tattctaaaa gaggaacgat tgaaggttat aggaaaggaa
      121 gagatgaatg gaacacaaag aacttacctc atttccaaaa gattttctgt ggggctctgc
      181 ttctgcagcg tatcaagtag aaggagcttg gcaagaagat gggaaaggag aatcagtctg
      241 ggatcgattt gtacggatac ctggaaagac atttaaagga acgaacggtg atttggcagt
      301 agaccactat catcgttata aagaagatat tgctttaatg aaagaacaag gtctgaaagc
      361 ttaccgcttc tctgtagctt ggacacggat ttttcctaat ggacgaggag aagtcaatca
      421 agctgggctc gctttttatg agagattgat cgacgaattg attgaaaacg atattgaacc
      481 tatgttgact ttatatcatt gggatcttcc acaagcattg caagatgaat ataatggttg
      541 ggaatcacgt cagatcattg aagatttcac tcattatgca gaaacattat ttgaggcatt
      601 ccgcgggaaa gtccattact ggattagttt gaatgaacaa aatatcttca cttcattagg
      661 ttatttgtta gcagcacatc cgccaggtgt gacagacccg aaacgaatgt atgaagttaa
      721 ccatattgct aatttagcaa atgcatctgt catcaataaa tttcacgagt tagaaatgcc
      781 tggaaaaatc ggaccaagct ttgcgtatac gccaaattat ccaattgaca gtaatcctga
      841 aaatgttctg gctgctgaaa atgcagaaga cctgatggcc aattattgga tggatgtcta
      901 tatgtgggga aaatatccga ttgctgccat gaggttctta gaagaaaaag gatgggcacc
      961 aacgattgaa gctggcgatg cagaattgct agaatctgct aaaccagatt ttcttgggat
     1021 caattactat caaacggcga cgaatgcatt caatccatta aacggagttg gtgctggaaa
     1081 aatgaatacg acaggaaaaa aaggttcatc agaagaaact ggagttcctg gaatgtataa
     1141 aaaagttgag aatccatttg tcgaacgaac aaattgggac tgggagattg acccagaagg
     1201 attaaggatc ggactgcgtc gtatcacaag ccgttaccgc atgccggtac tgattacgga
     1261 aaatggctta ggagagtatg acaagttgac agaagataaa caaatccatg acgactatcg
     1321 aatcaattac ttacaaagcc acgtcaaagc catcaaagaa gcaatttcgg atggagcaga
     1381 agtcctaggc tattgcacct ggtcttatac agatttgctt agctggctga acggttatca
     1441 aaagcgatat ggatttgtat atgttgatca agacgaaaca caagaaggat ctttggaacg
     1501 atataagaaa gacagttatt actggtacca aaaactgatt gaagaaaatg gagagaacct
     1561 ttagttcaca tacttaaaac aagaaggtac ggctggatat ggccgtgcct tttcttgata
     1621 aaatcattta gaaattaaga aaaactgtaa aataagctga aaaatgaaag aaagcgtcag
     1681 ttctttcaaa caaaacttta gttcccttac ttttttttgt ataatgaaac ttgatgaaat
     1741 gagggataat aaatggcaca aaagaaacgg cctactaaaa aaaggaaaaa gacgaaaaaa
     1801 acgaaaaagc aaaaacagca gcaggaacaa atgctgacga ttggtgttgg gtttgccttg
     1861 attttatttg ctgtcttcgg ctttttaaaa ttaggttttt taggaatatt gattgcaaac
     1921 ggctttcgga tcattgcagg aaatacttac caaatcctct gtcttttatt agccgtatta
     1981 ggattttgga ttgtcattaa gaatacagag ttttcaattg gtaaaaaccg acgctggttt
     2041 ggcggcatac tcttttattt cggtatctta ttattgttac atgcccattt atttggcaaa
     2101 ctccatactg gggaaccaaa tatcatgggg acgacatggg atttgttagc cagtgatata
     2161 aaacaaagtc aagtagacaa taacgttggt ggtgggatga ttggagcaat cctttatcat
     2221 tttacttact tcttgattgc acagcctgga agttatttag cagcagtgct attactggca
     2281 ggaggagcat tcctgttcag taatctggaa ggctatcagc tgttaaatgg tatccaatca
     2341 attggagaac gagtacagga attattggaa ggtgatcctg ccaagcaagc tcgaaagcaa
     2401 gcggcaaagg aagagagaat gaaacagcgc gcagaagcga aagaagcaag gcgcttagct
     2461 gcaaaagaag ctgcagaaaa agaagctgca gaatatgaga agaaaaaagc ggtgagccag
     2521 caaagggaaa atactgctga tgaatggcag gaaccagaaa atacagagcc ggagcagcta
     2581 agttttgttc caatcgacag ttttcaagaa aatatccatc ctgcgaatct agagaaacca
     2641 gtaccagata caccaaaaca gaccaataca gcagaaggtt tttcagatga gttgccagag
     2701 gatgacggta cctcattaga atttgagatt gaagcagaac aggaaaatca agactatgaa
     2761 ttaccgacag ttgatttgct tgattctata ccaactgtgg atcaaagtga tgagtataaa
     2821 aaaattgaaa aaaatatcgg cgtattagaa caaactttcc aaagtttcgg tgtcgatgcc
     2881 aaggtcgtca aagccagctt aggaccatcc gtcacaaaat tcgaagtcca gccggctgta
     2941 ggggtaaaag taagtaaaat tgtgaactta acagatgata tcgcgcttgc tttagcggcg
     3001 aaagatgtcc ggatggaagc accgattcca ggtaaatcac tgattggtat tgaagtacca
     3061 aatggaaaga tcagtatggt ttcctttaga gaaatcatcg aagcacaacc aaaccaccca
     3121 gataaattac tagaagtacc tttaggacgt gatgtttctg gacgggtaca aacggctgat
     3181 ctttcgaaga tgcctcactt actcgtggct ggttcgactg gtagtgggaa gtcagtagca
     3241 attaatggga ttatcacaag tatattaatg cgtgctaagc cccatgaagt aaaactgatg
     3301 atgatcgatc cgaaaatggt tgaattgaat atgtacaacg gcatacctca tctgttgacg
     3361 ccggtcgtga cgaaccctag aaaagcagcg caagccttac aaaaagtagt acaagaaatg
     3421 gaagaacgat atgaaaaatt cgcggcaacc ggagtaagaa atatttctgg ttacaatgaa
     3481 tttgttcaac agaaaaactt ggaaaacgga acgaaacatc caaccttacc attcatcgta
     3541 gtgatcgtag atgaattagc tgatttgatg atggtagcca gcaatgaagt tgaagatgcg
     3601 attattcgtt tagcgcaaat ggctcgggca gcggggattc atatgatcct agctactcaa
     3661 cgtccaagtg tggatgttat cacaggaatc atcaaagcaa atgtaccttc cagaatggca
     3721 tttgcggtat caagcggtac agattctcgg acgatcattg attctaatgg ggcagaaaag
     3781 ctcttagggc gaggagatat gctattcttg ccaatgggtg agaataaacc gatccgtgtg
     3841 caaggagcat tcatttctga ccacgaagta gaacgggtcg ttcaatttgt tacagatcag
     3901 caagaagctc attatgaaga gaaaatgatg ccgacagatg aagttgaaac gacaggtgct
     3961 ccagaacagc cacaagatga gctgtttgaa gaagcaaaag cacttgtcgt tgaaatgcaa
     4021 acggcaagta tttcccttct ccaaagaaga tttcggatcg gttacaaccg agcagcacgt
     4081 ttagtagatg aactggaagc tcatggagtt gttggcccgt cagaaggaag caagcctcgg
     4141 aaagtattca ttgagcagga agaaacatca gaaacgttgc cggacgataa tgacatgtaa
     4201 aacttgtgtg atgaagggtt gaaaaacgaa taaccaataa aaagacaagg catgatgata
     4261 ccaaaagaaa aaatggtttt tttccatctt ttctaatacg gtatgatgtc ttgtcttttt
     4321 agtttttgtg agattaaagt tctattcgat ttatttgtga agtattgcat taaggaaatg
     4381 aatcatgtat agtatgtagc gaaactttga gaaaaagagg gaaaatactt tggaaaaaca
     4441 gtccatttat ggcttgacga atgaagaatt aatcaattgg tttatagaaa acggcgagaa
     4501 aaaattccga gctgcccaag tttgggaatg gttgtatcaa aaacgtgtaa gtaatttcac
     4561 agaaatgacg aatctatcga aacaattgat cgaaaaatta tcggagcatt ttatcatcaa
     4621 tcctctaaaa cagatggtcg tccaagaagc ttcggatggt acagtaaaat atttgtttga
     4681 actccctgat aaaaacatga ttgagactgt actgatgaga caagaatatg gcttgtcagt
     4741 ttgtgtgacg acacaagtag gatgtaatat cggctgtacg ttttgtgcaa gcgggctgct
     4801 caaaaagaac cgtgatctga ctgctggaga aattgttgca cagatcatga tggtccaaca
     4861 ttattttgat gagcgcaatc ttggcgaacg cgtttcacat gtcgttgtaa tggggatcgg
     4921 tgagccattt gataattacg acaatgtaat ggactttttg catatcatca atgatgccaa
     4981 aggattggca attggtgctc ggcacattac agtttccact agtggattag cacacaaaat
     5041 caaggaattc gctaataacg gcttgcaagt caatctggct atttccttgc acgcgccgaa
     5101 taatgaggtg cgaacatcga tcatgcggat caaccgaagt ttcccaattg agaaattgat
     5161 ggaagctgtg gatgagtatt tagagaaaac aaaccgtcga atcacgtttg aatatatcat
     5221 gttgaatcaa gtaaatgata gaccagagca tgcgcaacaa ttagcagatc tattaaaaga
     5281 taagaaaaaa ttagcatatg tcaacttgat tccatataat ccagtcagtg aacatgatca
     5341 atattctcgc agtccaaaag ctgatgtatt gagattttat gatgtattga agaaaaacgg
     5401 cgtaaactgt gtgatacgta aagaacatgg tacagatatt gatgcagctt gcggacaatt
     5461 gcgaagcaag caaatgaaaa aaacagttgc caaataatcg tatcctactc gttttttcaa
     5521 ttaccataaa aggagcagtt ttcttaatta aggaactgtt caacttaaat aagagaaaag
     5581 attctatagc gaaagctata aagctttttt tgacaagaaa aaccctcatc aagcaaagaa
     5641 atgtcctcaa tttgatgaca gcctgcttga tgggggtttt agcaattatt taactgattt
     5701 tcttatatcc ttgctggctt tcttgtgtag catgataagt ttctacgtca agaatggcct
     5761 gtttaaattt ttctcgggtg atttcataag gcacatgttt aatatcattt gttgccatgg
     5821 ctttatctaa gattgcttct aaatcggtcg tgacattgag attcatgtcg gttaacgata
     5881 ctggaagttg gttctttttc ataaacacat agattttatc aaacaaatcg aactgctgat
     5941 ccatcatcaa taaggtcagt acaccataac tgacagatgc tccgtgaagg tatccctcca
     6001 ttttttctag aacagtcgta ccgtaataga atgagtgtgc catagcagaa ttatagttat
     6061 tgttaactaa aacagaaacc aatccggtag taacaatgat atccgaaacg acttgttcaa
     6121 ttgcatatga gggacgatcg tcggcactat ctttcaatgc ttgcgtacca taagtcaaga
     6181 gacgatcaat gcacattttt ccgatttgga ttcctaatct atccgtgtag cctagatcat
     6241 cgccacgagc agaaaaagta gattcgactt ctttggataa agcatcgcca atacctgccc
     6301 ataagtattt atcaggtgct tcggcaataa ttgctgtatc aatgaaggtg tgtacaggtg
     6361 gttttgaagg aaagaagagt ccgtccatta cgccttcttc gttatagatg acacataccg
     6421 cagtgacggg cgaacagttc gaaccaatag tgggaaaggt gaagactggt ttagctagtt
     6481 tttcaccaat gacttttaca gtatcgcaag cacggccacc accgactgca aacaggacgt
     6541 ctgctttttg gacactttca tgctggatca actgttcaat atttccataa gttgaattac
     6601 ccccgtacca gagactggcg acaacctcta tttcctgtgt caaagctact tttattttgt
     6661 tttctgcctt tgaaagtgca gtcttccctc caatcagcac tacttttgtc ccatattctt
     6721 tgacgattcc atttgctttt tcatacgcat ctgttccaat ggtataattt ggtaagaaaa
     6781 cactttgact catattcatt tccttctttc ttcgttgaaa cgggttaaaa ttttaaagag
     6841 tgatcgatct gactgcggct gtagatggag tagaggtgaa cctaagacag gataagtgat
     6901 gaataaggtg gcatgaacac cttgaaatca tcaataagta tcctaaaaac gaacaagtac
     6961 aaaaacattg aaaacgacaa taatgaattt ttgttcctct tagtatttct accgattccc
     7021 tttgcttttt tgtaattatc taaaaattct aaaaattaag attattatat gaaaacaggt
     7081 tttatttgtc aattcataat tggttttttt taaagcaaaa gataatctat atcatgatga
     7141 acaaacagag ttttttcctc caattgatgg ctttcctgat ctttcctatt ttgaataaag
     7201 tgtttctgta taattttttt attttataag taagataaat aatgaaagaa tagagatact
     7261 gattggtagc taaagatttt tgagcgagaa catttcgttt tttcaaaagg actgttagaa
     7321 taagcaagaa caagggggaa gacgtatgat aatcagtgaa tttgaccgta ataatccagt
     7381 attgaaagat cagctttctg atttactgag actgacttgg ccggaagaat atggagacag
     7441 ctcggcagaa gaagtagaag aaatgatgaa tccagaacga atcgcggtag cagcggtaga
     7501 ccaagatgag ttagtaggat ttattggtgc aatccctcaa tacggtatca caggttggga
     7561 attgcatcca ttagttgtag aaagctcccg acgaaagaac caaataggta ctcgattagt
     7621 caattactta gaaaaagaag tagcttccag aggaggaatc acgatttatt taggtacgga
     7681 tgatttagac catggaacaa cgttaagtca aacggacctg tatgagcata catttgataa
     7741 agtggcttcc atccagaacc ttcgtgaaca tccgtatgaa ttctatgaaa aattaggtta
     7801 taaaatcgta ggtgtcttac caaatgcaaa tggctgggac aaaccggata tttggatggc
     7861 aaaaacgatt attcctcgac caaattctca ataataaaaa gaggttgtga cagaagtaat
     7921 cagcttcaag aaataagaag gaatttacga aaattactt
//
LOCUS       DAZKKZ010000235         6179 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.guided.110, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000235 DAZKKZ010000000
VERSION     DAZKKZ010000235.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6179)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6179)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6179
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.guided.110"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..142)
                     /locus_tag="ACG8LA_003143"
     CDS             complement(<1..142)
                     /locus_tag="ACG8LA_003143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFQ0205332.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAF"
     gene            411..1307
                     /locus_tag="ACG8LA_003144"
     CDS             411..1307
                     /locus_tag="ACG8LA_003144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HFQ0205333.1"
                     /translation="MNKNDVLLVAKNKSLYFLPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFDMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMNFSSSEPKTDLFFGATNNGRKERAESYKQEFIKR
                     DVTTNYFILPHRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYHFYRPENIFLLRERDLDELPEFLHTPFKPILSELLEFYDAENWAKR
                     FITNDSTIYEQYEYDLSSVENK"
     gene            complement(1457..2398)
                     /locus_tag="ACG8LA_003145"
     CDS             complement(1457..2398)
                     /locus_tag="ACG8LA_003145"
                     /EC_number="1.1.1.169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008677 - 2-dehydropantoate 2-reductase
                     activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0015940 - pantothenate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HFQ0205334.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            2524..3645
                     /locus_tag="ACG8LA_003146"
     CDS             2524..3645
                     /locus_tag="ACG8LA_003146"
                     /EC_number="2.7.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008887 - glycerate kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HFQ0205335.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            3903..5405
                     /gene="eat(A)"
                     /locus_tag="ACG8LA_003147"
     CDS             3903..5405
                     /gene="eat(A)"
                     /locus_tag="ACG8LA_003147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection-like protein
                     Eat(A)"
                     /protein_id="HFQ0205336.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            5472..5999
                     /locus_tag="ACG8LA_003148"
     CDS             5472..5999
                     /locus_tag="ACG8LA_003148"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HFQ0205337.1"
                     /translation="MLYVTRHGETTWNAQGLVCGRADVPLTEKGQMQAQKLAEKVVDL
                     PVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYDGLPSKDENFQKAR
                     LAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIRVINAYFHPMPNEG
                     FFTFMVDNTELVSYE"
BASE COUNT         2038 a         1088 c         1265 g         1788 t
ORIGIN      
        1 aaaaagcaat caatacagaa gggccggcga tcccaatcgc ttcgccactt cctttaaata
       61 gacctgcacc gattgctcca cctaaagcta acatggtgat atgtctggag ctaagttgtt
      121 ttttcaattt tttatcttcc ataaatgacc tctttctttt aaattcacaa tcaaaattta
      181 tattaagaat aaatagcaat atttaacaat gactaatgat aacaaatttt cagacaatta
      241 caactattca gaaaactttt aggcgaattt taatagaaga atgatttatt tcatcatatt
      301 ttcatacaaa tgttaaattt tcatacaaat ataggaaacg ttttactggc tttttactat
      361 ttaaacaggc tatcatagga aaaagtgaca gagaaagtga ggcggaaaag atgaacaaaa
      421 atgacgtact gctagttgca aaaaataaat cactttattt tttgccttcc atccgctctt
      481 tagatgtttg gtccggaaaa gatttactac agtcggaatt cattaaatca gctagacaac
      541 agttggcaaa ttatcagctg atcgtttttt tagattatgg atttgatatg gagatggctc
      601 gacgcgtgcg cccatttacc aatgcaaaaa ttgtgttatt tttttggaat cacttcaaag
      661 cagaacacga ggcgatgctg aagcaggcac aagatgaacc ggcaatcgat gagatttatc
      721 attttgattt tttggaagca aaagaacttg ggctgaaaca taatagttca ttttattcga
      781 aacatatgaa tttttcttct agcgaaccaa agacggatct attttttggt gcaacgaata
      841 atgggagaaa agaacgagca gaaagctata agcaggaatt tataaaaaga gatgttacga
      901 ccaactattt cattcttcca catcgaggga atgaacaacc tggatatctt acttatgaag
      961 agtacctgaa aaaaacaggg gaatcgcgcg ggattctgga actgttgcgg gagggtcagc
     1021 aaggagtgac tttgcggaca tttgaatcca tgtattttca aaagaaacta gtgacggata
     1081 atcaagcgat tgctcattat catttttatc gtcctgaaaa tatttttttg cttcgagaac
     1141 gtgatttaga tgaattaccg gaatttctgc atacaccatt taagccaatc ctatcagagc
     1201 tattggaatt ttatgatgca gaaaattggg caaaacgatt tatcactaac gattccacta
     1261 tttatgagca atacgaatat gacctctcct ctgttgaaaa caaataaaaa acctacattt
     1321 tgaagagatt atgtactgaa acaaacaagc acaattctta tggcatcatg agagttgtgt
     1381 tttctttttg atcttttatt gggcttaaaa aaagagaacc agctgctgat tcagctgatt
     1441 ctcatcagag agccttttat tctgcgccaa ggattccttc ttttgcatgg actaattggg
     1501 tcaaaaaggc acaatatggt gtagcaatat catatttttg tccttttcgc caaatggcac
     1561 cattgatgta gtcgatttca gtcaaacgat ggtttttgat caggtcttgg tacatagatg
     1621 ggtaatgcaa cccgatgttg tcaggatcat aagtagaagc aatatgttgg tacacttctt
     1681 cttgatctag tatgattcct tcttttgctg cgatagaagc aaattcagat acgattgttc
     1741 gaaccatgct ctctgccgct ttttgcgcgc ctagttcagc aatattacaa tccaaaatcg
     1801 tgcataaacc attcaatgtt ccatttacac aagcttttcg ccaaatggaa taacgaacgt
     1861 tatggctata gatcggattt aaatttgctt cttgaaagac ttctacaact ttttttgtaa
     1921 atgcttcgcc ttctggttcc aagttctcta gttcgatttc tccatcacct aacaatgtga
     1981 cttttccggg accagctaga ccagctgtcc acatcgtgat cccaaataag atatttttct
     2041 ttggcacata tttttccagt acatcttcat gacctaatcc atttagtaaa cacaaaacat
     2101 aagtattgtc agtaataatg gattggatcg aacaaaacat atcatctaat tgattggctt
     2161 ttgttaatgc tacgatcaag tccacgtgtt cgttgctttc gatgatttct tctggtgaat
     2221 agattggcag ttttgcgacc acttctttac cgttaaagtc agcaatcaac ccatttgtac
     2281 gaatggcttc aatgtgagca ggccaacgat cgatcaagag gacctcattt ccgctttgat
     2341 gtagcatcaa tccgattcgg ctgcccattg ctccggcccc agctattgcg attttcatgt
     2401 tttttctctc ctttattcaa tgagttccct tttagtatat agaaaaatgg aagaaaatag
     2461 cattgttttg tttgaaaaaa atgaaaaaaa gtgtcttact taagaagaaa gtgagggata
     2521 cagatggata ttttggcggc aattgattca tttaaaggaa gtgcttcttc atttgaacta
     2581 aatcaggcag ttctaaatgg ctgggaagat cgtaaaggaa gaaaaatcaa tgtgccgatt
     2641 gcagatggcg gagaaaatac tgcagaagca atctattacg cgctcagggg aacatggcgt
     2701 accattgatg ggatggatct cttattccgt cagcgaaaaa tcagctattt attgacaact
     2761 tggcaaggaa aaaacaccgc agtcatcgaa tctgcacaag cattggggtt agatctactt
     2821 gataaaccaa cggatcaaac tatccgactt gcttccagtt atgccttagg agaacttatt
     2881 aaagatgcac tgcttcaaga agtagaacaa attattgtca ctttaggagg aagcgggtgt
     2941 agcgatggtg gtctaggatt actccaatcc ttgggtgctt ctttagaagg gtacacagaa
     3001 ggaaatcctt tattatctac taaaaaactt cattttgatc gaagaaacgt tcttgtttct
     3061 aaagtaaaat tgattatcgc tgcagatgtt accaatccat atacaggtca acaaggagct
     3121 gcttggcaat ttggaagaca aaaaggagga atagatacga cgctagcttt cttagataaa
     3181 caagcaggaa agattgctca gcaaataaaa gatttctggg aggtggattt agatgatatt
     3241 ccaggaagtg gagcagcagg cggtattggt ggagcccttt ttttgttggg agcgaagatg
     3301 gtttctggtt tcgatttagt cagccaaatc actggattgg aaaaaaagat cgaacaagca
     3361 gatgtcatca ttacaggaga agggcggatc gatcagcaaa cgatccacgg aaaagttcca
     3421 tacggtgtag cagtgcttgc aaaaaaatat cgaaaaccaa taatcgctat ttgcggaagt
     3481 agagaccaag agctagaagg actttctgat tttctcccaa ttgtcttaag tattcatttg
     3541 ggtccaatag gtttagaaga agcaatggaa cacaggcaaa cattagaaaa aacaaaaatc
     3601 ttaggacaga cacttagcag atttttcacc atcctcccga agtagttgac aaaatcattt
     3661 tctttatgct atcgtaattt caaatatagg acaaagtgag ggatccgtgc attgaaaaat
     3721 taagtcgatt gatgaaagct gcattcagac tgtaccttgt ggagacaagg aagcagtgtg
     3781 cagattttcg ggattggctt ggttttttcg atgtatgggt ctttttgtgt gtatccaacc
     3841 cttgcatcct ctttagccag ttctgaaaat aggactggtc tttttttacg aggtgatgga
     3901 aaatgtctaa aatcgaaata aaaaatctga cattcggcta cgacagccaa ggcacattat
     3961 tatttgaaca agcaaatcta aattttgaca cacaatggaa actaggactt atcggacgaa
     4021 acggtcgagg aaagacaact ttactgaata ttctacaaaa caaactacct tatcaagggc
     4081 aagtaatcca tcagcaagaa tttgcctatt tcccgcaaca gacaaaagat aaagaacgtt
     4141 taacctatta cgtgttaaat gatattacgg attttgagat atgggaaatc gaaagagagc
     4201 tccaattgat gcaaacagat cctgaaatct tatggagaga attcagcaca ctatcggggg
     4261 gagagaagac aaaagtccta ctggcacttt tatttgtgga tgacactcat ttcccgttaa
     4321 tcgatgaacc aacgaatcat ttggatatct ctggtagaaa acaagtagcg gcttatttga
     4381 aaaagaaaaa acaaggcttc atcgtggtca gccatgaccg gggatttatc gatgaagtag
     4441 tggaccatgt tttagcaatc gaaaaaagtc aactggaact ttatcaaggg aatttctcta
     4501 tctatgaaga acagaaaaaa cttcgtgatg aatttgaaat ggctcaaaat gaaaaattga
     4561 aaaaagaagt cagtaggcta aagaaaacag cagctgaaaa agccgaatgg tctcgttccc
     4621 gagaaggaga taaaacaaag aaacaagtcg gattcatcga tactgaatct agacgagtga
     4681 ataaaggagc agtgggtgct gatgctgcac ggacgatgaa acgatccaaa gcaatcgtga
     4741 atcggatgga gacccagatc agcgagaaag aaaaactatt aaaagatatc gaatatatcg
     4801 attctttgac gatgaatagc caagcgtctc accataagcg acttttaagc gtagaagatc
     4861 ttcaattagg gtatgaaaat ctgttattcg agccaattca ttttacaatc gagcctcatc
     4921 agcgggtggc gatttcaggt cctaacggtg caggaaagtc atccattatc cattatcttc
     4981 tgggggcatt caacggcaag gttataggag aaaaatacca gccaaaacat ctgagcatta
     5041 gttatgcaag ccaaaattat gaagacaatc gaggaacgtt ggcggaattt gcagagaaaa
     5101 accaagtaga ctaccaagca tttttgaaca acctccgaaa gcttgggatg gaaagagatg
     5161 tttttcataa caagatcgag cagatgagta tgggccaacg gaaaaaagtg gaattggcta
     5221 aatctttatc acagccagct gaactatata catgggatga accattgaat tatttggatg
     5281 tcttcaatca agaacaatta gaacaactga tcttgaacgt gaaacctgcc atgttactag
     5341 tggaacatga tcaaaccttc ctggataaag tatctactga gattatttct cttgagagaa
     5401 tctaaccctt gtaatctcaa gaacaacaag gtatggttaa ggggaacttt gccaacgaag
     5461 gagagaatca catgctttat gtaacgagac acggagaaac aacttggaac gcacaaggat
     5521 tagtttgcgg acgggcagat gtgccgctga ctgaaaaagg acagatgcag gcacagaaac
     5581 tagcagaaaa ggtagtagat ttgcctgttc caatcacgaa aatcatccat tcccctcttc
     5641 aacgagcaag agatacagca caagcagttg ctgatcgtct cagcttgccg ctgaccgttg
     5701 atgaacgatt ggtagaaatg gattttgggg attatgatgg actgccaagc aaagatgaga
     5761 actttcaaaa agcacgttta gcgttcgctg tacgattccc aaatggggag tcagtcttag
     5821 atgtgtatgc acggatcgtt cctttattga aagaatgcat cgaagacgaa gaaaatgtct
     5881 atctgttagt ttgccataat gccttgataa gagtgatcaa tgcttatttt catccgatgc
     5941 ctaatgaggg gttctttaca ttcatggtag ataatacaga attggtttct tatgagtaat
     6001 tatgtttttg tgttatttaa ataaaatatt tcaaggcact gcttttgctt agcagtgcct
     6061 tttttaggtt atgacaattc ttttgataat ataaactcaa cctttagaaa tgaaatttaa
     6121 ttattttaat aaaagtattg aaattttgtt tctttagata tatactctag tcatagaaa
//
LOCUS       DAZKKZ010000236         5614 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.guided.115, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000236 DAZKKZ010000000
VERSION     DAZKKZ010000236.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5614)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5614)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5614
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.guided.115"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            251..943
                     /locus_tag="ACG8LA_003149"
     CDS             251..943
                     /locus_tag="ACG8LA_003149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HFQ0205338.1"
                     /translation="MKKKFITGGIVVAFLCLIGYTGTRYANEIILWGGETDIDTINEN
                     LTQLDHTLTDKEQAITDLTARLAQKEQTLQDSKADVQEYQTKVNELENQKNQSAAEKQ
                     NLESQLVSKDAQLQSKQNEINVKLDEINQKNDEINHLNADWTARLQEAQAKLSELQNT
                     VNGLNQQIATLTQEKTNVETQLTDTQKKLDEATAENSSLKQYIQKLEKAKDEVEDTAD
                     KSQQIVEEHLRK"
     gene            1270..1767
                     /gene="dfrG"
                     /locus_tag="ACG8LA_003150"
     CDS             1270..1767
                     /gene="dfrG"
                     /locus_tag="ACG8LA_003150"
                     /EC_number="1.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004146 - dihydrofolate reductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrG"
                     /protein_id="HFQ0205339.1"
                     /translation="MKVSLIAAMDKNRVIGKENDIPWRIPKDWEYVKNTTKGHPIILG
                     RKNLESIGRALPDRRNIILTRDKGFTFNGCEIVHSIEDVFELCKNEEEIFIFGGEQIY
                     NLFFPYVEKMYITKIHHEFEGDTFFPEVNYEEWNEVFAQKGIKNDKNPYNYYFHVYER
                     KNLLS"
     gene            complement(1839..3791)
                     /locus_tag="ACG8LA_003151"
     CDS             complement(1839..3791)
                     /locus_tag="ACG8LA_003151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017431446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insertion element protein"
                     /protein_id="HFQ0205340.1"
                     /translation="MTKLKRLATKEDEIVDVKIPISNEELKDRAKQYDLLTPKRFATR
                     YNKMLFLPTSFKWNGSEYPIQYNYCINPFCCNFGKEQHKFKDVKGKPSRYKMTGSSKD
                     KGHKGMYCNDNPIGRGVSQNCTVTPLSNWSVVEEIKRLIEINSIQDVEPDYQFHKEGC
                     SEEESTPFNEPKQFYKRGKSRGKSQRYQCKACKKFTNVLPKREETTTYHQQKNTILPM
                     FAKMVVGRVSVSRTCDILGIGVGTYYHKLEWLYRRCLEFLERYETQPLQTKKFNEMWL
                     NTDKMHYYLNNVRKKGQGSKKYTGFEDLNMQTYIVVSAEVLSRYVFRSDVAYDWNISM
                     DELNEDTRKFKEDHLNTFSRKNDRLDWSYYPQEPSANDSENRNAYLHELGKITNRSRF
                     VDGLNVDAPYTTTAHYWLIKQMVNADEWRMISDDDFSIRNAFYRVFTKELRLSDAHHF
                     ICQVNKTKSRKQCLKEFGQAKAELLDWGDIRGFKTKFLRTLASHYLTELLTSHQFHEE
                     AISKDGERYRKYADNPIKHPLATKDKGFYSVDCRTDLSALEPNEIAKMLLNVNDHSTN
                     SFIQQIRRYISSLERPLTTARGDKKSYIYANFNPKYAQFAITILRTYYNFCRPFKSAD
                     KKVLTPAQRLGITDKQFDWKDIIYFK"
     gene            complement(3798..4034)
                     /locus_tag="ACG8LA_003152"
     CDS             complement(3798..4034)
                     /locus_tag="ACG8LA_003152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001159903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0205341.1"
                     /translation="MQFLEPKNKNAKSVDWEISEQVRVIVKQYAEYAERTESEAVDEF
                     LLNILDDKKFIEWIANKRSNKRIVEKMGIKDRVG"
     gene            4436..4726
                     /locus_tag="ACG8LA_003153"
     CDS             4436..4726
                     /locus_tag="ACG8LA_003153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0205342.1"
                     /translation="MEKKYGTVDKIRTLQVSARPLIRFSLNGVNCLIASHSLNFLAEV
                     DEGMKLVVTGYYNNRKQFVVRSYHVLGKPKIVVEYEKSLYPRKKVRQDERIN"
     gene            complement(4998..5347)
                     /locus_tag="ACG8LA_003154"
                     /pseudo
     CDS             complement(4998..5347)
                     /locus_tag="ACG8LA_003154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741963.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
BASE COUNT         1909 a          901 c          974 g         1830 t
ORIGIN      
        1 aaatgaaaag ggttacgttt aataaaactt gcttttttgt ttttgttcac cataaatatt
       61 tatttaagaa agtattaacc tgcatttttc tctataaaaa agatttttta aatagataaa
      121 aaaggaggat taaatgagta tttgatagta tttatattaa aattacatat gtaatttaaa
      181 aacgcttgac attgtgtttg agatcactta cttttagcat gtaaaagtat tggattaagg
      241 agctatgcaa atgaaaaaga aatttattac tggtgggatt gtcgttgcat ttctatgtct
      301 aattggctac acaggcacgc ggtacgcaaa tgaaattatt ttgtggggtg gagagacaga
      361 tattgataca atcaatgaga atctgacaca gcttgatcat acattgacag ataaagagca
      421 agcgattaca gatcttaccg ctcgactagc acaaaaagaa cagacattgc aagattcaaa
      481 ggcagatgtc caagaatacc aaacaaaagt aaatgaatta gaaaaccaaa aaaatcaatc
      541 ggcagcagaa aaacaaaact tagaaagtca attagtcagc aaggatgcac aactacaaag
      601 caaacaaaat gaaatcaatg tcaaactaga tgagatcaac caaaaaaatg atgaaatcaa
      661 tcatctgaat gcagattgga cagcaagact acaagaagca caagcaaaac tttcagaatt
      721 acaaaatact gtaaatggtt tgaatcaaca aatcgcaaca ctgacacaag aaaaaacaaa
      781 tgtagaaact cagttaacag atacacaaaa gaaattagac gaagcaactg ctgaaaactc
      841 aagcttgaaa caatatattc aaaagttaga aaaagcaaaa gatgaagtgg aagatacagc
      901 tgataaatct cagcaaattg ttgaagaaca tttgcgtaaa taatctttct taacaagtaa
      961 acctaaatta gtaaagaagc aacagtaatc tatactaagt agttcagttt tggagtacaa
     1021 aatgacaaaa tgtacttcaa aatggactac ttttttcatt ttaacttaca taccaaatta
     1081 catacaaaat gatttataaa atgcaattga aaatgataat tgaatgaaaa tttgtgattt
     1141 tgtggtatta tgataatata acttatagaa aaaattgctt attcaactaa cgggcaggat
     1201 aatgagaaaa ggttttttga tagaaataag aaattagatg gtaaattagt taaaaaggct
     1261 gtgttataaa tgaaagtttc tttgattgct gcgatggata agaatagagt gattggcaaa
     1321 gagaatgaca ttccttggag gattcccaag gactgggaat atgttaaaaa tactacaaag
     1381 ggacatccga taatattagg taggaagaac cttgaatcaa tcggaagagc cttacctgac
     1441 agaagaaata ttattctgac gagagataag gggtttacct ttaatggttg tgaaattgtt
     1501 cattcaatag aagatgtttt tgagttatgt aaaaacgaag aagaaatttt tattttcgga
     1561 ggagaacaga tttataattt gtttttccct tatgttgaga aaatgtacat cacaaaaata
     1621 catcatgaat tcgaaggaga tacttttttt ccagaagtga attatgagga atggaatgag
     1681 gtatttgccc aaaaagggat aaagaatgat aaaaatccgt ataactacta ttttcatgta
     1741 tatgaaagaa aaaacttatt gagttaacgg gtgcgttaat tgaagaagaa cagtaaagat
     1801 aaagcacaag agcttgggat tactccaagc tctttttgtc atttgaaata aattatatct
     1861 ttccaatcaa attgtttatc tgtaatccct aatctttgag caggtgtcaa aaccttttta
     1921 tccgctgatt taaaagggcg acaaaagttg tagtaagttc ttagaattgt aatcgcaaat
     1981 tgagcatact tcggattgaa gttagcgtaa atatagctct tcttatcacc acgagctgtt
     2041 gttaatggtc tttcaagaga tgatatataa cgtcttatct gttgaataaa gctattggtc
     2101 gaatggtcat taacatttaa tagcatcttt gcgatttcgt ttggttccag agcagataaa
     2161 tccgttctac aatcaactga ataaaatcct ttatccttag tggctaatgg atgtttgata
     2221 gggttatcgg catatttgcg atatctttct ccatctttac taatagcctc ttcgtggaat
     2281 tgatgacttg ttagtaattc agttagataa tgagatgcca aagtccgtag aaactttgtt
     2341 ttgaatcctc tgatatctcc ccaatcgagc agttctgctt ttgcttgtcc gaattctttt
     2401 aagcattgtt ttctgctttt cgtcttgtta acttggcaaa taaaatgatg tgcatcgctc
     2461 aaccttaatt ctttcgtgaa tactctataa aaggcgtttc taatagagaa gtcatcatca
     2521 ctaatcattc gccattcgtc ggcattaacc atttgtttaa ttaaccaata gtgagcagtt
     2581 gtagtataag gagcatcaac atttaaacca tcgacaaatc tactcctatt agtaattttc
     2641 cctaattcgt gaagataagc attcctattt tcgctatcgt tagcggatgg ttcttgtgga
     2701 taataagacc aatctaacct atcattttta cgactaaaag tattgagatg gtcttctttg
     2761 aattttcttg tatcttcatt taattcatcc attgaaatat tccaatcata ggcaacatca
     2821 gaacggaaca catatcttga taagacctca gcagatacaa ctatatacgt ttgcatatta
     2881 aggtcttcaa accccgtata tttctttgaa ccttgtcctt tcttacggac gttatttagg
     2941 tagtagtgca tcttgtccgt attaagccac atctcgttaa atttctttgt ttgaaggggt
     3001 tgtgtctcat atcgttctaa aaactccaaa caacgcctat acagccactc cagcttatga
     3061 tagtaggttc caactccaat tcctaaaata tcacaagtac gactgactga aacccttcca
     3121 acaaccatct tagcgaacat tggaagaatg gtgttctttt gttggtgata agtagtggtt
     3181 tcttctcttt ttggtagaac attagtgaac ttcttacacg ccttacattg atagcgttga
     3241 gatttgcccc tacttttccc ccttttgtaa aattgcttcg gctcattgaa tggggttgat
     3301 tcttcttccg agcagccttc tttatgaaat tgataatctg gctcaacatc ttggatgcta
     3361 ttgatttcta taaggcgttt aatttcttca acaacagacc aattagataa aggggttact
     3421 gtacagtttt gcgatacacc tctgccaata ggattgtcat tgcagtacat acctttatga
     3481 cctttatctt tggaactacc agtcatttta tatcgacttg gtttcccttt tacatctttg
     3541 aatttgtgct gttctttccc aaaattacaa caaaacggat tgatgcagta attatattga
     3601 atgggatatt cagaaccgtt ccatttaaaa gacgttggca agaacaacat tttgttatac
     3661 cttgttgcaa atcgttttgg agttaataaa tcatattgtt tagccctatc ttttaattct
     3721 tcgtttgaaa tcggaatttt aacatctaca atttcatctt ccttcgtggc taatctttta
     3781 agcttggtca ttgtctatca acccactcta tctttgatac ccattttttc aacaatccgc
     3841 ttattacttc gcttgttggc aatccattca ataaacttct tatcgtctaa aatgttcaat
     3901 aagaattcat ccactgcttc gctttcagta cgctctgcat attcagcgta ttgcttaact
     3961 atcaccctta cttgctctga tatttcccaa tccacagact tagcgttctt attttttggc
     4021 tcaagaaatt gcataggaaa atgcacccct ttttgcttag taaattgtaa ccattttaac
     4081 acaccaattt gcattcctac aataattatt tcacgttcgc atttttatat acattttaac
     4141 ttacattttg tggtgtaaat taacaacaaa cgttgattta acaataaaaa acgagtatca
     4201 aattcagttg caatttgata ctcatttagg tttacatttt cactttttgt actccaaaac
     4261 tgaactactt aaatctatac tgctgcctct tttttttagt acatgtcctt catcttcgca
     4321 ggaagtgcca atatgatttt aagaaaggta atagacaaaa agtcaaaaag ataaaacaga
     4381 gtttcttctt tacaaaggga atgtatgttc gtataatggt attgaggtga aggttatgga
     4441 gaaaaaatat ggaacagtag ataagatccg tactttgcaa gttagtgcca gaccgttgat
     4501 ccgtttcagt ttaaatgggg tcaattgttt gattgcttcc catagtttga acttcctagc
     4561 tgaagtagac gaagggatga agttagtcgt tacaggttat tataataata gaaagcaatt
     4621 tgttgtgaga tcctatcatg tgttagggaa acccaaaatt gtggtagaat atgagaaaag
     4681 tctataccca agaaaaaagg tccgacaaga tgaaagaata aactagaaaa caagcggctg
     4741 agacaaaaat gtcctagccg cttgttttgg aaagatggat gcagacgatg ggatttgaac
     4801 ccacacgagc atacgctcac aagaacctca atctatatat aactacatgt atttaagtat
     4861 ttgtgatgaa tcactaaact ttccaaactc atttgaggga tattgcttaa agattgaaca
     4921 gatcaattcg aagccctatt agtattcgct caatgggggg atcagaggcc ataaaaagag
     4981 actagtcatt actagtctca ggtagtggaa ttgtaggatt ttaaacgttc ctggagagta
     5041 ccggtatgta actcgaagag gtgattatca tagtcgtaaa agtaaattga agaagcctcg
     5101 cctttcacac gagaacgtcc tggttcgaca gttaaaccta acatttggat ttttgagaca
     5161 aacgaatcta tatcttgttc gtcaatttta aaagcaatat gattgtatgt ctttggcagt
     5221 ttattcgacg aattctgcat tactgcaatc cataggtcct taactaagaa aaatttttct
     5281 ggatataatg aaaatttttt tgttgactat cgtagatttc ttttgcatca aataaggtat
     5341 ttaacaatta agtatttaaa agataacttt taagttatct ttaagtaatg cttaaagcta
     5401 tgttatactc tattaggaaa tataagaagg agtataaaaa tgaacaaaca taatagaaaa
     5461 ataacgaata acaaagaact gatcttgtta ctaataggga tttggggtat ctttttactc
     5521 tttaatatgt atatgccgac tatgagagcg gatgacgtag tttatgcaag tagattagat
     5581 gaacttggct atttgggtgc ttcgatagaa catt
//
LOCUS       DAZKKZ010000237         4151 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.guided.133, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000237 DAZKKZ010000000
VERSION     DAZKKZ010000237.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4151)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4151)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4151
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.guided.133"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            260..1171
                     /locus_tag="ACG8LA_003155"
     CDS             260..1171
                     /locus_tag="ACG8LA_003155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala carboxypeptidase VanY-A"
                     /protein_id="HFQ0205343.1"
                     /translation="MKKLFFLLLLLFLIYLGYDYVNEALFSQEKVEFQNYDQNPKEHL
                     ENSGTSENTQEKTITEEQVYQGNLLLINSKYPVRQESVKSDIVNLSKHDELINGYGLL
                     DSNIYMSKEIAQKFSEMVNDAVKGGVSHFIINSGYRDFDEQSVLYQEMGAEYALPAGY
                     SEHNSGLSLDVGSSLTKMERAPEGKWIEENAWKYGFILRYPEDKTELTGIQYEPWHIR
                     YVGLPHSAIMKEKNFVLEEYMDYLKEEKTISVSVNGEKYEIFYYPVTKNTTIHVPTNL
                     RYEISGNNIDGVIVTVFPGSTHTNSRR"
     gene            1324..1809
                     /gene="vanZ-A"
                     /locus_tag="ACG8LA_003156"
     CDS             1324..1809
                     /gene="vanZ-A"
                     /locus_tag="ACG8LA_003156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance protein VanZ-A"
                     /protein_id="HFQ0205344.1"
                     /translation="MGKILSRGLLALYLVTLIWLVLFKLQYNILSVFNYHQRSLNLTP
                     FTATGNFREMIDNVIIFIPFGLLLNVNFKEIGFLPKFAFVLVLSLTFEIIQFIFAIGA
                     TDITDVITNTVGGFLGLKLYGLSNKHMNQKKLDRVIIFVGILLLVLLLVYRTHLRINY
                     V"
     gene            2328..2612
                     /locus_tag="ACG8LA_003157"
     CDS             2328..2612
                     /locus_tag="ACG8LA_003157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFQ0205345.1"
                     /translation="MELAFRESLKKMRGTKSKEKFSQELEMSRSNYSRIESGKSDPTI
                     KTLEQIAKLTNSTLVVDLIPNEPTEPEPETESEQVTLDLEMEEEKSNDFV"
     gene            2978..3277
                     /locus_tag="ACG8LA_003158"
     CDS             2978..3277
                     /locus_tag="ACG8LA_003158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0205346.1"
                     /translation="MNHDECKTYIKNSLLEIRKLANIYTLETFKKELEKRNIYLETKS
                     DKYFSSEGEDYIYKLIENNKIIYSISGKKLTYKGKKSFSKHAILKQLNEKANQVN"
     gene            3320..>4151
                     /locus_tag="ACG8LA_003159"
     CDS             3320..>4151
                     /locus_tag="ACG8LA_003159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017284764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein RepR"
                     /protein_id="HFQ0205347.1"
                     /translation="MNIPFVVETVLHDGLLKYKFKNSKIRSITTKPGKSKGAIFAYRS
                     KSSMIGGRGVVLTSEEAIQENQDTFTHWTPNVYRYGTYADENRSYTKGHSENNLRQIN
                     TFFIDFDIHTAKETISASDILTTAIDLGFMPTMIIKSDKGYQAYFVLETPVYVTSKSE
                     FKSVKAAKIISQNIREYFGKSLPVDLTCNHFGIARIPRTDNVEFFDPNYRYSFKEWQD
                     WSFKQTDNKGFTRSSLTVLSGTEGKKQVDEPWFNLLLHETKFSGEKGLTELGRSRPSS
                     I"
BASE COUNT         1537 a          609 c          756 g         1249 t
ORIGIN      
        1 ccttatttga tagtagattt aaaactttgc aacagaaccc ccattgtcaa caggcagttc
       61 agcctcgtta aattcagcat gggtatcact tatgaaaatt catctacatt ggtgataata
      121 gtaaatccag tagggcgaaa taattgactg taatttacgg ggcaaaacgg cacaatctca
      181 aacgagattg tgccgtttaa ggggaagatt ctagaaatat ttcatacttc caactatata
      241 gttaaggagg agactgaaaa tgaagaagtt gtttttttta ttgttattgt tattcttaat
      301 atacttaggt tatgactacg ttaatgaagc actgttttct caggaaaaag tcgaatttca
      361 aaattatgat caaaatccca aagaacattt agaaaatagt gggacttctg aaaataccca
      421 agagaaaaca attacagaag aacaggttta tcaaggaaat ctgctattaa tcaatagtaa
      481 atatcctgtt cgccaagaaa gtgtgaagtc agatatcgtg aatttatcta aacatgacga
      541 attaataaat ggatacgggt tgcttgatag taatatttat atgtcaaaag aaatagcaca
      601 aaaattttca gagatggtca atgatgctgt aaagggtggc gttagtcatt ttattattaa
      661 tagtggctat cgagactttg atgagcaaag tgtgctttac caagaaatgg gggctgagta
      721 tgccttacca gcaggttata gtgagcataa ttcaggttta tcactagatg taggatcaag
      781 cttgacgaaa atggaacgag cccctgaagg aaagtggata gaagaaaatg cttggaaata
      841 cgggttcatt ttacgttatc cagaggacaa aacagagtta acaggaattc aatatgaacc
      901 atggcatatt cgctatgttg gtttaccaca tagtgcgatt atgaaagaaa agaatttcgt
      961 tctcgaggaa tatatggatt acctaaaaga agaaaaaacc atttctgtta gtgtaaatgg
     1021 ggaaaaatat gagatctttt attatcctgt tactaaaaat accaccattc atgtgccgac
     1081 taatcttcgt tatgagatat caggaaacaa tatagacggt gtaattgtga cagtgtttcc
     1141 cggatcaaca catactaatt caaggaggta aggatggcgg aatgaaacca acgaaattaa
     1201 tgaacagcat tattgtacta gcacttttgg ggtaacgtta gctttttaat ttaaaaccca
     1261 cgttaactag gacattgcta tactaatgat acaacttaaa caaaagaatt agaggaaatt
     1321 atattgggaa aaatattatc tagaggattg ctagctttat atttagtgac actaatctgg
     1381 ttagtgttat tcaaattaca atacaatatt ttatcagtat ttaattatca tcaaagaagt
     1441 cttaacttga ctccatttac tgctactggg aatttcagag agatgataga taatgttata
     1501 atctttattc catttggctt gcttttgaat gtcaatttta aagaaatcgg atttttacct
     1561 aagtttgctt ttgtactggt tttaagtctt acttttgaaa taattcaatt tatcttcgct
     1621 attggagcga cagacataac agatgtaatt acaaatactg ttggaggctt tcttggactg
     1681 aaattatatg gtttaagcaa taagcatatg aatcaaaaaa aattagacag agttattatt
     1741 tttgtaggta tacttttgct cgtattattg ctcgtttacc gtacccattt aagaataaat
     1801 tacgtgtaag atgtctaaat caagcaatct gatctttcat acacataaag atattgaatg
     1861 aattggatta gatggaaaac gggatgtggg gaaactcgcc cgtaggtgtg aagtgagggg
     1921 aaaaccggtg ataaagtaaa aagcttacct aacactatag taacaaagaa agcccaatta
     1981 tcaattttag tgctgaggaa ttggtctctt taataaattt ccttaacgtt gtaaatccgc
     2041 attttcctga cggtaccccc actagcagcc atgctttttt tgaatctttg taggacgttt
     2101 taaagagaat tacccacttt aaaattaaac atgcgcttag aatcgcttta ggaaacacga
     2161 tccagtccaa taatcgtcga taaaaacttt tgaaaaaggt tggtgaaatt acctactttt
     2221 ggaataatca caaatcacaa gtgattaatc acttgtttat taagatatta aaagctataa
     2281 tttaaataaa gcgtgaattt tattacacaa aaagaggggg gagaaacttg gaactagcat
     2341 ttagagaaag cttaaaaaag atgagaggta ccaaatcaaa agaaaaattc tcccaagaat
     2401 tagaaatgag tagatcaaat tattcacgaa tagaatcagg aaaatcagat ccaaccataa
     2461 aaacactaga acaaattgca aagttaacta actcaacgct agtagtggat ttaatcccaa
     2521 atgagccaac agaaccagaa ccagaaacag aatcagaaca agtaacattg gatttagaaa
     2581 tggaagaaga aaaaagcaat gacttcgtgt gaataatgca cgaaatcgtt gcttattttt
     2641 tttaaaagcg gtatactaga tataacgaaa caacgaactg aatagaaacg aaaaaagagc
     2701 catgacacat ttataaaatg tttgacgaca ttttataaat gcatagcccg ataagattgc
     2761 caaaccaacg cttatcagtt agtcagatga actcttccct cgtaagaagt tatttaatta
     2821 actttgtttg aagacggtat ataaccgtac tatcattata tagggaaatc agagagtttt
     2881 caagtatcta agctactgaa tttaagaatt gttaagcaat caatcggaaa tcgtttgatt
     2941 gctttttttg tattcattta tagaaggtgg agtttgtatg aatcatgatg aatgtaaaac
     3001 ttatataaaa aatagtttat tggagataag aaaattagca aatatctata cactagaaac
     3061 gtttaagaaa gagttagaaa agagaaatat ctacttagaa acaaaatcag ataagtattt
     3121 ttcttcggag ggggaagatt atatatataa gttaatagaa aataacaaaa taatttattc
     3181 gattagtgga aaaaaattga cttataaagg aaaaaaatct ttttcaaaac atgcaatatt
     3241 gaaacagttg aatgaaaaag caaaccaagt taattaaaca acctatttta taggatttat
     3301 aggaaaggag aacagctgaa tgaatatccc ttttgttgta gaaactgtgc ttcatgacgg
     3361 cttgttaaag tacaaattta aaaatagtaa aattcgctca atcactacca agccaggtaa
     3421 aagcaaaggg gctatttttg cgtatcgctc aaaatcaagc atgattggcg gtcgtggtgt
     3481 tgttctgact tccgaggaag cgattcaaga aaatcaagat acatttacac attggacacc
     3541 caacgtttat cgttatggaa cgtatgcaga cgaaaaccgt tcatacacga aaggacattc
     3601 tgaaaacaat ttaagacaaa tcaatacctt ctttattgat tttgatattc acacggcaaa
     3661 agaaactatt tcagcaagcg atattttaac aaccgctatt gatttaggtt ttatgcctac
     3721 tatgattatc aaatctgata aaggttatca agcatatttt gttttagaaa cgccagtcta
     3781 tgtgacttca aaatcagaat ttaaatctgt caaagcagcc aaaataattt cgcaaaatat
     3841 ccgagaatat tttggaaagt ctttgccagt tgatctaacg tgtaatcatt ttggtattgc
     3901 tcgcatacca agaacggaca atgtagaatt ttttgatcct aattaccgtt attctttcaa
     3961 agaatggcaa gattggtctt tcaaacaaac agataataag ggctttactc gttcaagtct
     4021 aacggtttta agcggtacag aaggcaaaaa acaagtagat gaaccctggt ttaatctctt
     4081 attgcacgaa acgaaatttt caggagaaaa gggtttaaca gaattaggca gaagtcgccc
     4141 atcctctata g
//
LOCUS       DAZKKZ010000238         3965 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.guided.136, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000238 DAZKKZ010000000
VERSION     DAZKKZ010000238.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3965)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3965)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3965
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.guided.136"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..1081
                     /gene="vanS"
                     /locus_tag="ACG8LA_003160"
     CDS             <1..1081
                     /gene="vanS"
                     /locus_tag="ACG8LA_003160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="vancomycin resistance histidine kinase VanS"
                     /protein_id="HFQ0205348.1"
                     /translation="YLIVDLKLCNRTRSMIRGKLGDWILSILENKYDLNHLDAMKLYQ
                     YSIRNNIDIFIYVAIVISILILCRVMLSKFAKYFDEINTGIDVLIQNEDKQIELSAEM
                     DVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVMYLAHDIKTPLTSIIGYLSLLDEAPD
                     MPVDQKAKYVHITLDKAYRLEQLIDEFFEITRYNLQTITLTKTHIDLYYMLVQMTDEF
                     YPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFNNILKNAAAYSEDNSIIDITAGLSGD
                     VVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSSDTGGAGLGLAIAKEIIVQHGGQIYA
                     ESNDNYTTFRVELPAMPDLVDKRRS"
     gene            1296..2264
                     /locus_tag="ACG8LA_003161"
     CDS             1296..2264
                     /locus_tag="ACG8LA_003161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="HFQ0205349.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKS
                     APFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAY
                     SPDSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKA
                     VIERLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQ
                     RMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQ
                     FLLKLQRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
     gene            2257..3288
                     /gene="vanA"
                     /locus_tag="ACG8LA_003162"
     CDS             2257..3288
                     /gene="vanA"
                     /locus_tag="ACG8LA_003162"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008716 - D-alanine-D-alanine ligase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanA"
                     /protein_id="HFQ0205350.1"
                     /translation="MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGIT
                     KSGVWKMCEKPCAEWENDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKS
                     GEDGSIQGLFELSGIPFVGCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPV
                     AATFTYPVFVKPARSGSSFGVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCA
                     VLGNSAALVVGEVDQIRLQYGIFRIHQEVEPEKGSENAVITVPADLSAEERGRIQETA
                     KKIYKALGCRGLARVDMFLQDNGRIVLNEVNTLPGFTSYSRYPRMMAAAGIALPELID
                     RLIVLALKG"
     gene            3294..3902
                     /locus_tag="ACG8LA_003163"
     CDS             3294..3902
                     /locus_tag="ACG8LA_003163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="HFQ0205351.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTY
                     ELAESLLKAKELAATQGYGLLLWDGYRPKRAVNCFMQWAAQPENNLTKESYYPNIDRT
                     EMISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEA
                     QNRRRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
BASE COUNT         1201 a          766 c          943 g         1055 t
ORIGIN      
        1 ttatttgata gtagatttaa aactttgcaa cagaacccgt tcaatgatcc gagggaaact
       61 tggggattgg atcttaagta ttttggaaaa caaatatgac ttaaatcacc tggacgcgat
      121 gaaattatat caatattcca tacggaacaa tatagatatc tttatttatg tggcgattgt
      181 cattagtatt cttattctat gtcgcgtcat gctttcaaaa ttcgcaaaat actttgacga
      241 gataaatacc ggcattgatg tacttattca gaacgaagat aaacaaattg agctttctgc
      301 ggaaatggat gttatggaac aaaagctcaa cacattaaaa cggactctgg aaaagcgaga
      361 gcaggatgca aagctggccg aacaaagaaa aaatgacgtt gttatgtact tggcgcacga
      421 tattaaaacg ccccttacat ccattatcgg ttatttgagc ctgcttgacg aggctccaga
      481 catgccggta gatcaaaagg caaagtatgt gcatatcacg ttggacaaag cgtatcgact
      541 cgaacagcta atcgacgagt tttttgagat tacacggtat aacctacaaa cgataacgct
      601 aacaaaaacg cacatagacc tatactatat gctggtgcag atgaccgatg aattttatcc
      661 tcagctttcc gcacatggaa aacaggcggt tattcacgcc cccgaggatc tgaccgtgtc
      721 cggcgaccct gataaactcg cgagagtctt taacaacatt ttgaaaaacg ccgctgcata
      781 cagtgaggat aacagcatca ttgacattac cgcgggcctc tccggggatg tggtgtcaat
      841 cgaattcaag aacactggaa gcatcccaaa agataagcta gctgccatat ttgaaaagtt
      901 ctataggctg gacaatgctc gttcttccga tacgggtggc gcgggacttg gattggcgat
      961 tgcaaaagaa attattgttc agcatggagg gcagatttac gcggaaagca atgataacta
     1021 tacgacgttt agggtagagc ttccagcgat gccagacttg gttgataaaa ggaggtccta
     1081 agagatgtat ataatttttt aggaaaatct caaggttatc tttacttttt cttaggaaat
     1141 taacaattta atattaagaa acggctcgtt cttacacggt agacttaata ccgtaagaac
     1201 gagccgtttt cgttcttcag agaaagattt gacaagatta ccattggcat ccccgtttta
     1261 tttggtgcct ttcacagaaa gggttggtct taattatgaa taacatcggc attactgttt
     1321 atggatgtga gcaggatgag gcagatgcat tccatgctct ttcgcctcgc tttggcgtta
     1381 tggcaacgat aattaacgcc aacgtgtcgg aatccaacgc caaatccgcg cctttcaatc
     1441 aatgtatcag tgtgggacat aaatcagaga tttccgcctc tattcttctt gcgctgaaga
     1501 gagccggtgt gaaatatatt tctacccgaa gcatcggctg caatcatata gatacaactg
     1561 ctgctaagag aatgggcatc actgtcgaca atgtggcgta ctcgccggat agcgttgccg
     1621 attatactat gatgctaatt cttatggcag tacgcaacgt aaaatcgatt gtgcgctctg
     1681 tggaaaaaca tgatttcagg ttggacagcg accgtggcaa ggtactcagc gacatgacag
     1741 ttggtgtggt gggaacgggc cagataggca aagcggttat tgagcggctg cgaggatttg
     1801 gatgtaaagt gttggcttat agtcgcagcc gaagtataga ggtaaactat gtaccgtttg
     1861 atgagttgct gcaaaatagc gatatcgtta cgcttcatgt gccgctcaat acggatacgc
     1921 actatattat cagccacgaa caaatacaga gaatgaagca aggagcattt cttatcaata
     1981 ctgggcgcgg tccacttgta gatacctatg agttggttaa agcattagaa aacgggaaac
     2041 tgggcggtgc cgcattggat gtattggaag gagaggaaga gtttttctac tctgattgca
     2101 cccaaaaacc aattgataat caatttttac ttaaacttca aagaatgcct aacgtgataa
     2161 tcacaccgca tacggcctat tataccgagc aagcgttgcg tgataccgtt gaaaaaacca
     2221 ttaaaaactg tttggatttt gaaaggagac aggagcatga atagaataaa agttgcaata
     2281 ctgtttgggg gttgctcaga ggagcatgac gtatcggtaa aatctgcaat agagatagcc
     2341 gctaacatta ataaagaaaa atacgagccg ttatacattg gaattacgaa atctggtgta
     2401 tggaaaatgt gcgaaaaacc ttgcgcggaa tgggaaaacg acaattgcta ttcagctgta
     2461 ctctcgccgg ataaaaaaat gcacggatta cttgttaaaa agaaccatga atatgaaatc
     2521 aaccatgttg atgtagcatt ttcagctttg catggcaagt caggtgaaga tggatccata
     2581 caaggtctgt ttgaattgtc cggtatccct tttgtaggct gcgatattca aagctcagca
     2641 atttgtatgg acaaatcgtt gacatacatc gttgcgaaaa atgctgggat agctactccc
     2701 gccttttggg ttattaataa agatgatagg ccggtggcag ctacgtttac ctatcctgtt
     2761 tttgttaagc cggcgcgttc aggctcatcc ttcggtgtga aaaaagtcaa tagcgcggac
     2821 gaattggact acgcaattga atcggcaaga caatatgaca gcaaaatctt aattgagcag
     2881 gctgtttcgg gctgtgaggt cggttgtgcg gtattgggaa acagtgccgc gttagttgtt
     2941 ggcgaggtgg accaaatcag gctgcagtac ggaatctttc gtattcatca ggaagtcgag
     3001 ccggaaaaag gctctgaaaa cgcagttata accgttcccg cagacctttc agcagaggag
     3061 cgaggacgga tacaggaaac ggcaaaaaaa atatataaag cgctcggctg tagaggtcta
     3121 gcccgtgtgg atatgttttt acaagataac ggccgcattg tactgaacga agtcaatact
     3181 ctgcccggtt tcacgtcata cagtcgttat ccccgtatga tggccgctgc aggtattgca
     3241 cttcccgaac tgattgaccg cttgatcgta ttagcgttaa aggggtgata agcatggaaa
     3301 taggatttac ttttttagat gaaatagtac acggtgttcg ttgggacgct aaatatgcca
     3361 cttgggataa tttcaccgga aaaccggttg acggttatga agtaaatcgc attgtaggga
     3421 catacgagtt ggctgaatcg cttttgaagg caaaagaact ggctgctacc caagggtacg
     3481 gattgcttct atgggacggt taccgtccta agcgtgctgt aaactgtttt atgcaatggg
     3541 ctgcacagcc ggaaaataac ctgacaaagg aaagttatta tcccaatatt gaccgaactg
     3601 agatgatttc aaaaggatac gtggcttcaa aatcaagcca tagccgcggc agtgccattg
     3661 atcttacgct ttatcgatta gacacgggtg agcttgtacc aatggggagc cgatttgatt
     3721 ttatggatga acgctctcat catgcggcaa atggaatatc atgcaatgaa gcgcaaaatc
     3781 gcagacgttt gcgctccatc atggaaaaca gtgggtttga agcatatagc ctcgaatggt
     3841 ggcactatgt attaagagac gaaccatacc ccaatagcta ttttgatttc cccgttaaat
     3901 aaacttttaa ccgttgcacg gacaaacggt tctgttgcaa agttttaaat aaagaataaa
     3961 atccc
//
LOCUS       DAZKKZ010000239         3621 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.guided.140, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000239 DAZKKZ010000000
VERSION     DAZKKZ010000239.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3621)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3621)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3621
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.guided.140"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(1..998)
                     /locus_tag="ACG8LA_003164"
                     /pseudo
     CDS             complement(1..998)
                     /locus_tag="ACG8LA_003164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase"
     gene            1489..2427
                     /locus_tag="ACG8LA_003165"
     CDS             1489..2427
                     /locus_tag="ACG8LA_003165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HFQ0205352.1"
                     /translation="MKKIDEKLAAEISLKKPAVSNSRLSNSRLSGQTLGKSQPALSFD
                     AMTIVGNLNKTNAKKLSDFMSVEPQIRLWDILQTKFKAKALQEKVYIEYDKVKADTWD
                     RRNMRVEFNPNKLTHEEMIWLKQNIIDYMEDDGFTRLDLAFDFEDDLSDYYAMTDKAV
                     KKTVFYGRNGKPETKYFGVRDSDRFIRIYNKKQERKDNADVEVVSEHLWRVEVELKRD
                     MVDYWNDCFNDLHILKPAWATLEKINEQAMVYTLLHEESMWGKLSKNTKTKFKKLIRE
                     ISPIDLTELMKSTLKANEKQLQKQIDFWQREFRFWK"
     gene            2557..3204
                     /locus_tag="ACG8LA_003166"
     CDS             2557..3204
                     /locus_tag="ACG8LA_003166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type A-7 chloramphenicol O-acetyltransferase"
                     /protein_id="HFQ0205353.1"
                     /translation="MTFNIIELENWDRKEYFEHYFNQQTTYSITKEIDITLFKDMIKK
                     KGYEIYPSLIYAIMEVVNKNKVFRTGINSENKLGYWDKLNPLYTVFNKQTEKFTNIWT
                     ESDKNFISFYNNYKNDLLEYKDKEEMFPKKPIPENTIPISMIPWIDFSSFNLNIGNNS
                     SFLLPIITIGKFYSENNKIYIPVALQLHHSVCDGYHASLFMNEFQDIIHRVDDWI"
BASE COUNT         1216 a          529 c          606 g         1270 t
ORIGIN      
        1 aatacaatat tgttgccaca cttaggacat tttcctacaa tacttttttc tgcttctttt
       61 tctttctgtt cctggtaatc agaaaaattt agtttttcta tatcgttagg tacagcttcc
      121 agtaaatgaa caatgaattt tttgatattc gtaataaagt tctcttgatt gccttctctt
      181 ttaccgattt tttttaaata cgtttcccat ttagccgtca tttcagcact cgttaaaagg
      241 tgctgacttt caactgcctg gcacaataat tttccttttt cagttacaac aagcttattc
      301 ttaatcactt ggatatattc tttttgtttt aacgcttcaa taatacttgc tcttgtcgct
      361 tctgttccaa tcccctcaac ttcttgtaaa atcttgattg cttcttcatc atcaaccgtt
      421 ttattcgccg ttttcatagc agttaataat gtaccctctg taaaagcttt tggcggttgc
      481 gtttcttttt caacactctt aacaccaact tcggcacgtt cgccaatgat aacgagtggt
      541 aacgtttgaa cgtcctcttt ttcttctttg gtttgttgtt tgaaaagaat tttccaccct
      601 tcttgctttg gtgtctttcc gatcgattga aacagcaaat cagctacttt cgtttgtatc
      661 ttggtttctt catacaagta atcaggtaaa aacatggcaa cggtcgtttt aacgactaaa
      721 gcataaattt ttcgttgtaa atcgtccatt ttcgctaatg cagattcggt aggtacttgt
      781 tttgttggga taatggcgtg gtgttcctgt accttactac cgtccacata acgctttcta
      841 ggctctgttt gaaccatttc aagatcaagt cctaaaaaac cgctatattt gccaaaattc
      901 gcttttaaat aagcaaattc gttctctgta ataaatggtg tatctgttct tggataactc
      961 aataattttg cttcatacag tccttgcata gcttttaaac gtaaaatttt gcgttctaag
     1021 acgttttaaa tatatctgcg tatattttta tgtgttttat cttttcgtcg gcaaatgcgt
     1081 taaaatttgc gaaataaaat agctcaaggg cgaacgcagt gagtgcattt acccttgatc
     1141 tatttttttg agtaaattag cttttgaaac cgacggaaag gaaacacaaa acttttcaga
     1201 ggcaaggggt ttttaagggg cgcttttagc cccttgaatt tatttgcttt aagatatatt
     1261 tagttttaaa atagttttaa cgaaaaaaag acataaaaaa agacgagcaa cgctaccaac
     1321 gttctcgccc ggaataacaa accacacttg ttattcattc gatgattagt atatcaattt
     1381 ttgattttga atacaaaaca aaatggacga atggatacag gcgaaattta ttttgcgatt
     1441 ccactcgtcc ttttttcgtt ccaaaaatta ttttaggagc gataaaaaat gaagaaaatt
     1501 gatgaaaaat tagctgcaga aatctcacta aaaaaaccgg ccgtctctaa tagccggtta
     1561 agtaatagcc ggttaagtgg tcaaactttg ggaaaatctc aacccgcatt aagttttgat
     1621 gccatgacaa tcgttggaaa tttgaacaaa actaatgcta aaaagctatc tgactttatg
     1681 agtgtagagc cacaaatacg actttgggat atacttcaaa caaagtttaa agctaaggca
     1741 cttcaagaaa aagtttatat cgaatatgac aaagtaaaag cagatacttg ggatagacgt
     1801 aatatgcgtg ttgaatttaa tcccaataaa ctcacacatg aagaaatgat ttggttaaaa
     1861 caaaatatta tcgactacat ggaagatgac ggttttacaa gattagactt agcttttgat
     1921 tttgaagatg atttgagcga ttactatgca atgactgata aagcagttaa gaaaactgtt
     1981 ttttatggtc gtaatggcaa gccagaaaca aaatattttg gtgtccgtga tagtgataga
     2041 tttattagaa tttataataa aaaacaagaa cgtaaagata acgcagatgt tgaagttgtg
     2101 tctgaacatt tatggcgtgt agaagttgaa ttaaaaagag atatggttga ttactggaat
     2161 gattgtttta atgatttaca catcttgaaa cctgcgtggg ctactttaga aaaaattaat
     2221 gagcaagcta tggtttatac tttgttgcat gaagaaagta tgtggggaaa gctaagtaag
     2281 aatactaaga ctaaatttaa aaaattgatt agagaaatat ctccaattga tttaacggaa
     2341 ttaatgaaat cgactttaaa agcgaacgaa aaacaattgc aaaagcagat tgatttttgg
     2401 caacgtgaat ttaggttttg gaagtaaaat aagttttatt tgataaaaat tgctaattca
     2461 gtataattaa tatttacgag gtgacataac gtatgaaaaa atcagaggat tattcctcct
     2521 aaatataaaa atttaaaatt taggaggaag ttatatatga cttttaatat tattgaatta
     2581 gaaaattggg atagaaaaga atattttgaa cactatttta atcagcaaac tacttatagc
     2641 attactaaag aaattgatat tactttgttt aaagatatga taaaaaagaa aggatatgaa
     2701 atttatccct ctttaattta tgcaattatg gaagttgtaa ataaaaataa agtgtttaga
     2761 acaggaatta atagtgagaa taaattaggt tattgggata agttaaatcc tttgtataca
     2821 gtttttaata agcaaactga aaaatttact aacatttgga ctgaatctga taaaaacttc
     2881 atttcttttt ataataatta taaaaatgac ttgcttgaat ataaagataa agaagaaatg
     2941 tttcctaaaa aaccgatacc tgaaaacacc ataccgattt caatgattcc ttggattgat
     3001 tttagttcat ttaatttaaa tattggtaac aatagcagct ttttattgcc tattattacg
     3061 ataggtaaat tttatagtga gaataataaa atttatatac cagttgctct gcaacttcat
     3121 cattctgtat gtgatggtta ccatgcttca ctatttatga atgaatttca agatataatt
     3181 catagggtag atgattggat ttagttttta gattttgaaa gtgaatttaa ttttatacac
     3241 gtaagtgatc ataaaattta tgaacgtata acaaccacat tttttggttg cttgtggttt
     3301 tgattttgaa tttggttttg aacttatgga ctgatttatt cagtccattt tttgtgcttg
     3361 cacaaaaact agcctcgcag agcacacgca ttaatgactt atgaaacgta gtaaataagt
     3421 ctagtgtgtt atactttact tggaagatgc accgaataaa aaatattgaa gaacaactag
     3481 caaaagattt taaagagtta ttttatttta agtctttata acatgagtga agcgaatttt
     3541 taaatttcga tagaaatttt tacatcaaaa agccccctgt caaaattgac gaagggggtt
     3601 ttttggcgca cgcttttcgt t
//
LOCUS       DAZKKZ010000240         3277 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.guided.146, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000240 DAZKKZ010000000
VERSION     DAZKKZ010000240.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3277)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3277)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3277
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.guided.146"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            3..188
                     /locus_tag="ACG8LA_003167"
     CDS             3..188
                     /locus_tag="ACG8LA_003167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018579902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0205354.1"
                     /translation="MNISVSELARRIGQTPQNFNKKLQRETVTLDELKAIADVLGVKF
                     VQAFILPDGEEIKISNE"
     gene            203..1072
                     /locus_tag="ACG8LA_003168"
     CDS             203..1072
                     /locus_tag="ACG8LA_003168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HFQ0205355.1"
                     /translation="MVGNVIQIVTEKLSSLPFIEGIVLGGSRARGTHTENSDIDIGIY
                     YNSDSFDLTAINQIATELDDKNRNNLVVPPGAWGDWINGGGWLFINGYHVDLILRDIK
                     RVEQIIKDTEQGIVTANYQTGHPHGYISAMYRGELAISKILYAKNESLCELKKQAEIY
                     PTALKKSLMNFFIFEAEFSLMFVKANAGVEDKYYIAGHVFRIISCLNQVLFACNNAYC
                     INEKKAIKLLETFEYKPEKYAERVNHIFEVLGLSLFECYDMTEKLYKEVNEIVSEINN
                     FLNEESSDERKQI"
     gene            1053..1787
                     /locus_tag="ACG8LA_003169"
     CDS             1053..1787
                     /locus_tag="ACG8LA_003169"
                     /EC_number="2.1.1.222"
                     /EC_number="2.1.1.64"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008425 -
                     2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0061542 - 3-demethylubiquinol-n
                     3-O-methyltransferase activity [Evidence IEA];
                     GO_function: GO:0102208 - 2-polyprenyl-6-hydroxyphenol
                     methylase activity [Evidence IEA];
                     GO_process: GO:0006744 - ubiquinone biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFQ0205356.1"
                     /translation="MKENKYDDNIFFQKYSQMSRSQKGLAGAGEWETLKKMLPDFKGK
                     RVLDLGCGYGWHCIYAMENGASSVVGVDISHKMLEVAKGKTHFPQIEYECCAIEDVDF
                     PEESFDVILSSLAFHYVADYENLIKKIYRMLKAGGNLVFTVEHPVFTAHGTQDWYYNE
                     KGEILHFPVDNYYYEGKRTAMFLEEKVTKYHRTLTTYLNTLLSNSFIINQIVEPQPPE
                     NMMDIPGMADEMRRPMMLIVSAKKKM"
     gene            1820..2728
                     /locus_tag="ACG8LA_003170"
     CDS             1820..2728
                     /locus_tag="ACG8LA_003170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside nucleotidyltransferase ANT(6)-Ia"
                     /protein_id="HFQ0205357.1"
                     /translation="MRSEKEMMDLVLSLAEQDERIRIVTLEGSRANINIPKDEFQDYD
                     ITYFVSDIEPFISNDDWLNQFGNIIMMQKPEDMELFPPEEKGFSYLMLFDDYNKIDLT
                     LLPLEELDNYLKGDKLIKVLIDKDCRIKRDIVPTDIDYHVRKPSAREYDDCCNEFWNV
                     TPYVIKGLCRKEILFAIDHFNQIVRHELLRMISWKVGIETGFKLSVGKNYKFIERYIS
                     EDLWEKLLSTYRMDSYENIWEALFLCHQLFRAVSGEVAERLHYAYPEYDRNITKYTRD
                     MYKKYTGKTGCLDSTYAADIEERREQ"
     gene            2725..3205
                     /locus_tag="ACG8LA_003171"
                     /pseudo
     CDS             2725..3205
                     /locus_tag="ACG8LA_003171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
BASE COUNT         1146 a          465 c          718 g          948 t
ORIGIN      
        1 aaatgaatat aagtgtttcc gaacttgcta gacgtattgg ccagactcca cagaatttca
       61 ataaaaaatt acaacgagaa acagtaacct tggatgagtt gaaggccatt gctgatgtgc
      121 taggtgtcaa gtttgtgcag gcatttattt taccagatgg agaagaaata aaaatatcta
      181 acgaataaag gaggatgttt atatggtagg taatgttatt caaatagtaa cagagaaatt
      241 atcatctttg ccttttatag aaggcatcgt attagggggc tcacgtgcaa gaggcaccca
      301 tacagaaaat tctgatatag atatcggaat ctattacaat tcagactcat ttgacctgac
      361 agcgattaat caaattgcta cagaattgga tgataaaaat agaaacaacc ttgttgtgcc
      421 tcccggagcg tggggtgatt ggattaatgg cggcggatgg ttatttataa atgggtatca
      481 tgttgacttg attttacgtg atataaaacg ggtagaacaa ataatcaaag atacggagca
      541 aggaattgtt actgccaatt atcagaccgg gcatccccat ggttatataa gtgcaatgta
      601 tcgtggagaa ttagcgatta gtaaaatact atatgctaag aacgaaagct tatgcgaatt
      661 aaaaaagcag gcagaaattt accctactgc tctaaagaaa agcttgatga acttttttat
      721 atttgaagct gaattctctt taatgtttgt aaaagcaaat gcgggggtag aggataaata
      781 ttatattgca ggccatgttt ttcgtattat ttcatgctta aatcaagtac tatttgcatg
      841 taataatgct tattgcatta acgaaaagaa agctataaaa ctgcttgaaa cttttgaata
      901 taaacctgaa aaatatgccg aaagagttaa tcatattttt gaagtactcg gtctttctct
      961 ttttgaatgc tacgatatga ccgagaaact ttataaagaa gtgaatgaaa ttgtatcgga
     1021 gataaataac tttttaaacg aggagagttc agatgaaaga aaacaaatat gatgataata
     1081 tattttttca aaaatacagt caaatgagtc gctcgcagaa aggactggct ggtgcgggag
     1141 aatgggagac tttgaaaaag atgctacctg attttaaggg taagcgtgtg cttgatttag
     1201 gatgcggcta tggatggcac tgtatatatg cgatggaaaa cggtgcttcc tctgtagtag
     1261 gtgttgatat ttctcataaa atgctcgaag tagcaaaagg aaaaacccat tttccacaga
     1321 ttgaatatga atgctgtgcc atagaagatg tggatttccc agaggagagc tttgatgtaa
     1381 tactaagttc gcttgcgttt cattatgtag cagactatga gaatttaata aaaaagatat
     1441 ataggatgct gaaggctggt ggcaatttag tttttacagt tgaacatcct gtttttactg
     1501 ctcatggaac acaagactgg tattataacg aaaaaggaga aatactgcat ttcccggtgg
     1561 acaattatta ttatgagggc aaacggacag ctatgttttt ggaagaaaag gttacaaaat
     1621 atcatagaac actgaccaca tatctaaata cactgctttc aaatagtttt ataataaatc
     1681 agattgtgga gccacagccg ccagagaaca tgatggatat tccggggatg gcggatgaaa
     1741 tgcgacgccc aatgatgctg attgtatcgg caaaaaagaa gatgtaataa tatagaaaaa
     1801 ataaacgagg agtatgtaaa tgagatcaga aaaagaaatg atggatttag tactttcttt
     1861 agcagaacag gatgaacgta ttcgaattgt gacccttgag gggtcacgcg caaatattaa
     1921 tatacctaaa gatgaatttc aggattatga tattacatat tttgtaagtg atatagaacc
     1981 gtttatatct aatgatgact ggcttaatca atttgggaat ataataatga tgcaaaagcc
     2041 ggaggatatg gaattattcc cacctgaaga aaagggattt tcctatctta tgctatttga
     2101 tgattacaat aaaattgatc ttaccttatt gcccttggaa gagttagata attacctaaa
     2161 gggcgataaa ttaataaagg ttctaattga taaagattgt agaattaaaa gggacatagt
     2221 tccgactgat atagattatc atgtaagaaa gccaagcgca agggagtatg atgattgctg
     2281 caatgaattt tggaatgtaa caccttatgt tattaaagga ttgtgccgta aggaaatttt
     2341 atttgctatt gatcatttta atcagattgt tcgccatgag ctgctgagaa tgatatcatg
     2401 gaaggtcggc atcgaaacag gctttaaatt aagtgtaggc aagaactata agtttattga
     2461 aaggtatata tccgaggatt tgtgggagaa acttttgtcc acctaccgga tggattccta
     2521 tgaaaacata tgggaagcat tatttctatg ccatcaattg ttcagggcgg tatccggtga
     2581 ggtggcggaa aggcttcatt atgcctatcc ggagtatgat aggaatataa caaaatatac
     2641 cagggacatg tataaaaaat acactggtaa aaccggctgc ctggatagca catatgccgc
     2701 tgatatagaa gagaggcggg aacagtgatt acagaaatga aagcagggca cctgaaagat
     2761 atcgataaac ccagcgaacc atttgaggtg ataggtaaga ttataccgag gtatgaaaac
     2821 gagaattgga cctttacaga attactctat gaagcgccat atttaaaaag ctaccaagac
     2881 gaagaggatg aagaggatga ggaggcagat tgccttgaat atattgacaa tactgataag
     2941 ataatatatc ttttatatag aagatatcgc cgtatgtaag gatttcaggg ggcaaggcat
     3001 aggcagcgcg cttatcaata tatctataga atgggcaaag cataaaaact tgcatggact
     3061 aatgcttgaa acccaggaca ataaccttat agcttgtaaa ttctatcata attgtggttt
     3121 caaaatcggc tccgtcgata ctatgttata cgccaacttt gaaaacaact ttgaaaaagc
     3181 tgttttctgg tatttaaggt tttagaatgc aaggaacagt gaattggagt tcgtcttgtg
     3241 gttctgttgc aaagttttaa ataaagaata aaatccc
//
LOCUS       DAZKKZ010000241         2827 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.guided.155, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000241 DAZKKZ010000000
VERSION     DAZKKZ010000241.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2827)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2827)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2827
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.guided.155"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..1348
                     /locus_tag="ACG8LA_003172"
     CDS             <1..1348
                     /locus_tag="ACG8LA_003172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="bifunctional aminoglycoside N-acetyltransferase
                     AAC(6')-Ie/aminoglycoside O-phosphotransferase
                     APH(2'')-Ia"
                     /protein_id="HFQ0205358.1"
                     /translation="DFILYLKLCNRTESLKKHYTEPWEDEVFRVIIEYNNVPIGYGQI
                     YKMYDELYTDYHYPKTDEIVYGMDQFIGEPNYWSKGIGTRYIKLIFEFLKKERNANAV
                     ILDPHKNNPRAIRAYQKSGFRIIEDLPEHELHEGKKEDCYLMEYRYDDNATNVKAMKY
                     LIEHYFDNFKVDSIEIIGSGYDSVAYLVNNEYIFKTKFSTNKKKGYAKEKAIYNFLNT
                     NLETNVKIPNIEYSYISDELSILGYKEIKGTFLTPEIYSTMSEEEQNLLKRDIASFLR
                     QMHGLDYTDISECTIDNKQNVLEEYILLRETIYNDLTDIEKDYIESFMERLNATTVFE
                     GKKCLCHNDFSCNHLLLDGNNRLTGIIDFGDSGIIDEYCDFIYLLEDSEEEIGTNFGE
                     DILRMYGNIDIEKAKEYQDIVEEYYPIETIVYGIKNIKQEFIENGRKEIYKRTYKD"
     gene            complement(1478..2650)
                     /locus_tag="ACG8LA_003173"
     CDS             complement(1478..2650)
                     /locus_tag="ACG8LA_003173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS256 family transposase"
                     /protein_id="HFQ0205359.1"
                     /translation="MTQVHFTLKSEEIQSIIEYSVKDDVSKNILTTVFNQLMENQRTE
                     YIQAKEYERTENRQSQRNGYYERSFTTRVGTLELKVPRTRDGHFSPTVFERYQRNEKA
                     LMASMLEMYVSGVSTRKVSKIVEELCGKSVSKSFVSSLTEQLEPMVNEWQNRLLSEKN
                     YPYLMTDVLYIKVREENRVLSKSCHIAIGITKDGDREIIGFMIQSGESEETWTTFFEY
                     LKERGLQGTELVISDAHKGLVSAIRKSFTNVSWQRCQVHFLRNIFTTIPKKNSKSFRE
                     AVKGIFKFTDINLAREAKNRLIHDYIDQPKYSKACASLDDGFEDAFQYTVQGNSHNRL
                     KSTNLIERLNQEVRRREKIIRIFPNQTSANRLIGAVLMDLHDEWIYSSRKYINFDK"
BASE COUNT          991 a          360 c          494 g          982 t
ORIGIN      
        1 ggattttatt ctttatttaa aactttgcaa cagaaccgaa tcattaaaaa aacattatac
       61 agagccttgg gaagatgaag tttttagagt aattattgaa tataacaatg ttcctattgg
      121 atatggacaa atatataaaa tgtatgatga gttatatact gattatcatt atccaaaaac
      181 tgatgagata gtctatggta tggatcaatt tataggagag ccaaattatt ggagtaaagg
      241 aattggtaca agatatatta aattgatttt tgaatttttg aaaaaagaaa gaaatgctaa
      301 tgcagttatt ttagaccctc ataaaaataa tccaagagca ataagggcat accaaaaatc
      361 tggttttaga attattgaag atttgccaga acatgaatta cacgagggca aaaaagaaga
      421 ttgttattta atggaatata gatatgatga taatgccaca aatgttaagg caatgaaata
      481 tttaattgag cattactttg ataatttcaa agtagatagt attgaaataa tcggtagtgg
      541 ttatgatagt gtggcatatt tagttaataa tgaatacatt tttaaaacaa aatttagtac
      601 taataagaaa aaaggttatg caaaagaaaa agcaatatat aattttttaa atacaaattt
      661 agaaactaat gtaaaaattc ctaatattga atattcgtat attagtgatg aattatctat
      721 actaggttat aaagaaatta aaggaacttt tttaacacca gaaatttatt ctactatgtc
      781 agaagaagaa caaaatttgt taaaacgaga tattgccagt tttttaagac aaatgcacgg
      841 tttagattat acagatatta gtgaatgtac tattgataat aaacaaaatg tattagaaga
      901 gtatatattg ttgcgtgaaa ctatttataa tgatttaact gatatagaaa aagattatat
      961 agaaagtttt atggaaagac taaatgcaac aacagttttt gagggtaaaa agtgtttatg
     1021 ccataatgat tttagttgta atcatctatt gttagatggc aataatagat taactggaat
     1081 aattgatttt ggagattctg gaattataga tgaatattgt gattttatat acttacttga
     1141 agatagtgaa gaagaaatag gaacaaattt tggagaagat atattaagaa tgtatggaaa
     1201 tatagatatt gagaaagcaa aagaatatca agatatagtt gaagaatatt atcctattga
     1261 aactattgtt tatggaatta aaaatattaa acaggaattt atcgaaaatg gtagaaaaga
     1321 aatttataaa aggacttata aagattgatt atataatata tgaaaagcta ttataaaaga
     1381 cattagtatt aaatagttta aaaaaatgaa aaataataaa ggaagtgagt caagtccaga
     1441 ctcctgtgta aaatgctata caatgttttt accatttcta cttatcaaaa ttgatgtatt
     1501 ttcttgaaga ataaatccat tcatcatgta ggtccataag aacggctcca attaagcgat
     1561 tggctgatgt ttgattgggg aagatgcgaa taatcttttc tcttctgcgt acttcttgat
     1621 tcagtcgttc aattagattg gtactcttta gtcgattgtg ggaatttcct tgtacggtat
     1681 attgaaaggc gtcttcgaat ccatcatcca atgatgcgca agcttttgaa tattttggtt
     1741 gatcgatata atcatgaatc aatcgatttt tagcctcacg cgctaagtta atatctgtga
     1801 acttaaaaat tcctttaaca gcttctctga aagattttga atttttttta ggaatggtgg
     1861 taaagatatt tcttaggaag tgaacttggc atctttgcca acttacgttg gtgaaggatt
     1921 ttctaatggc agagactaat cctttgtgcg catcagaaat aacgagttcc gtaccttgta
     1981 aaccgcgttc ttttaggtat tcaaaaaatg ttgtccaggt ctcttcgctt tcgccacttt
     2041 gaatcatgaa gccgataatt tcacggtcgc catctttggt tattccaatc gctatatgac
     2101 agctttttga gagtactcga ttttcttctc gtacttttat atagagtaca tcggtcatta
     2161 agtaaggata atttttttct gataataaac gattctgcca ctcgttaacc ataggttcta
     2221 gctgttctgt taagctagaa acgaaggact tagagacgga tttaccacaa agttcttcca
     2281 caatttttga tactttacga gttgaaacgc ctgatacata catttccaac attgaagcca
     2341 tgagggcttt ttcgtttcgt tgataacgtt caaacactgt gggtgaaaaa tggccatcac
     2401 gtgttctggg tacttttaat tctagcgtgc ctacacgtgt cgtaaagctg cgctcataat
     2461 agccatttcg ttgactttgt cggttttctg ttcgttcata ttcttttgct tgaatatatt
     2521 ctgttcgttg attttccatt agttgattaa ataccgttgt taaaatattt ttagaaacgt
     2581 catcctttac agaatattca ataatgcttt gaatctcttc gcttttcagt gtaaaatgta
     2641 cttgggtcat gtaaaagtcc tcctgggtat gtttttgtcg ttaaaaacat tgtaccgtaa
     2701 aaggactgtt atatggcctt tttactttta cacaattata cggactttat ctatataaag
     2761 gcgctgtcag agttttttga cttagaacat acattcattc aagagacttt aaacaagcta
     2821 gcagaac
//
LOCUS       DAZKKZ010000242         1149 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.guided.202, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000242 DAZKKZ010000000
VERSION     DAZKKZ010000242.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1149)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1149)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1149
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.guided.202"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            27..77
                     /locus_tag="ACG8LA_003174"
     CDS             27..77
                     /locus_tag="ACG8LA_003174"
                     /inference="COORDINATES: protein motif:HMM:NF018061.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0031556 - transcriptional attenuation by
                     ribosome [Evidence IEA];
                     GO_process: GO:0046677 - response to antibiotic [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HFQ0205360.1"
                     /translation="MWTLSKQTKNSDYADK"
     gene            202..939
                     /gene="erm(B)"
                     /locus_tag="ACG8LA_003175"
     CDS             202..939
                     /gene="erm(B)"
                     /locus_tag="ACG8LA_003175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011100845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HFQ0205361.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGNIP
                     YHLSTQIIKKVVFESRASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTITYEQVLSIFNSYLLFNGRK"
BASE COUNT          421 a          200 c          185 g          343 t
ORIGIN      
        1 catggccttt tatcttttac acaattatat ggactttatc gaaacagact aaaaacagtg
       61 attacgcaga taaataaata cgttagatta attcctacca gtgactaatc ttatgacttt
      121 ttaaacagat aactaaaatt acaaacaaat cgtttaactt ctgtatttgt ttatagatgt
      181 aatcacttca ggagagatta catgaacaaa aatataaaat attctcaaaa ctttttaacg
      241 agtgaaaaag tactcaacca aataataaaa caattgaatt taaaagaaac cgataccgtt
      301 tacgaaattg gaacaggtaa agggcattta acgacgaaac tggctaaaat aagtaaacag
      361 gtaacgtcta ttgaattaga cagtcatcta ttcaacttat cgtcagaaaa attaaaactg
      421 aatactcgtg tcactttaat tcaccaagat attctacagt ttcaattccc taacaaacag
      481 aggtataaaa ttgttgggaa tattccttac catttaagca cacaaattat taaaaaagtg
      541 gtttttgaaa gccgtgcgtc tgacatctat ctgattgttg aagaaggatt ctacaagcgt
      601 accttggata ttcaccgaac actagggttg ctcttgcaca ctcaagtctc gattcagcaa
      661 ttgcttaagc tgccagcgga atgctttcat cctaaaccaa aagtaaacag tgtcttaata
      721 aaacttaccc gccataccac agatgttcca gataaatatt ggaagctata tacgtacttt
      781 gtttcaaaat gggtcaatcg agaatatcgt caactgttta ctaaaaatca gtttcatcaa
      841 gcaatgaaac acgccaaagt aaacaattta agtaccatta cttatgagca agtattgtct
      901 atttttaata gttatctatt atttaacggg aggaaataat tctatgagtc gcttttttaa
      961 atttggaaag ttacacgtta ctaaagggaa tggagataaa ttattagata tactactgac
     1021 agcttccaag aagctaaaga ggtccctagc gcctacgggg aatttgtatc gataaggggt
     1081 acaaattccc actaagcgct cgggacccct tgtaggaaaa tgtcctaagt gtggcaacaa
     1141 tattgtatt
//
LOCUS       DAZKKZ010000243          921 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3843
            SAMEA115706951-rid22570143.guided.214, whole genome shotgun
            sequence.
ACCESSION   DAZKKZ010000243 DAZKKZ010000000
VERSION     DAZKKZ010000243.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706951
            Sequence Read Archive: ERR13196685
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 921)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 921)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287836.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287836.1
            Genome Coverage       :: 177x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 07:36:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,177
            CDSs (total)                      :: 3,115
            Genes (coding)                    :: 3,018
            CDSs (with protein)               :: 3,018
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 41 of 97
            Pseudo Genes (incomplete)         :: 50 of 97
            Pseudo Genes (internal stop)      :: 31 of 97
            Pseudo Genes (multiple problems)  :: 21 of 97
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..921
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706951-rid22570143.guided.214"
                     /isolate="VRE3843"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            92..787
                     /gene="vanR-A"
                     /locus_tag="ACG8LA_003176"
     CDS             92..787
                     /gene="vanR-A"
                     /locus_tag="ACG8LA_003176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin resistance response regulator
                     transcription factor VanR-A"
                     /protein_id="HFQ0205362.1"
                     /translation="MSDKILIVDDEHEIADLVELYLKNENYTVFKYYTAKEALECIDK
                     SEIDLAILDIMLPGTSGLTICQKIRDKHTYPIIMLTGKDTEVDKITGLTIGADDYITK
                     PFRPLELIARVKAQLRRYKKFSGVKEQNENVIVHSGLVINVNTHECYLNEKQLSLTPT
                     EFSILRILCENKGNVVSSELLFHEIWGDEYFSKSNNTITVHIRHLREKMNDTIDNPKY
                     IKTVWGVGYKIEK"
     gene            765..887
                     /locus_tag="ACG8LA_003177"
                     /pseudo
     CDS             765..887
                     /locus_tag="ACG8LA_003177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance histidine kinase
                     VanS"
BASE COUNT          312 a          168 c          188 g          253 t
ORIGIN      
        1 catggccttt tatcttttac acaattatat ggactttatc ctataatctg ataaattatt
       61 aagggcaaac ttatgtgaaa gggtgataac tatgagcgat aaaatactta ttgtggatga
      121 tgaacatgaa attgccgatt tggttgaatt atacttaaaa aacgagaatt atacggtttt
      181 caaatactat accgccaaag aagcattgga atgtatagac aagtctgaga ttgaccttgc
      241 catattggac atcatgcttc ccggcacaag cggccttact atctgtcaaa aaataaggga
      301 caagcacacc tatccgatta tcatgctgac cgggaaagat acagaggtag ataaaattac
      361 agggttaaca atcggcgcgg atgattatat aacgaagccc tttcgcccac tggagttaat
      421 tgctcgggta aaggcccagt tgcgccgata caaaaaattc agtggagtaa aggagcagaa
      481 cgaaaatgtt atcgtccact ccggccttgt cattaatgtt aacacccatg agtgttatct
      541 gaacgagaag cagttatccc ttactcccac cgagttttca atactgcgaa tcctctgtga
      601 aaacaagggg aatgtggtta gctccgagct gctatttcat gagatatggg gcgacgaata
      661 tttcagcaag agcaacaaca ccatcaccgt gcatatccgg catttgcgcg aaaaaatgaa
      721 cgacaccatt gataatccga aatatataaa aacggtatgg ggggttggtt ataaaattga
      781 aaaataaaaa aaacgactat tccaaactag aacgaaaact ttacatgtat atcgttgcaa
      841 ttgttgtggt agcaattgta ttcgtgttgt atattcgttc aatggttctg ttgcaaagtt
      901 ttaaataaag aataaaatcc c
//
